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Sample records for bian zhou siyuan

  1. Thorium and uranium redox-active ligand complexes; reversible intramolecular electron transfer in U(dpp-BIAN)2/ U(dpp-BIAN)2(THE)

    Energy Technology Data Exchange (ETDEWEB)

    Schelter, Eric John [Los Alamos National Laboratory; Wu, Ruilian [Los Alamos National Laboratory; Scott, Brian L [Los Alamos National Laboratory; Thompson, Joe D [Los Alamos National Laboratory; Batista, Enrique R [Los Alamos National Laboratory; Morris, David E [Los Alamos National Laboratory; Kiplinger, Jaqueline L [Los Alamos National Laboratory

    2008-01-01

    Actinide complexes of the redox-active ligand dpp-BIAN{sup 2-} (dpp-BIAN = bis(2,6-diisopropylphenyl)acenaphthylene), An(dpp-BIAN){sub 2}(THF){sub n} (An = Th, n = 1; An = U, n = 0, 1) have been prepared. Solid-state magnetic and single-crystal X-ray data for U(dpp-BIAN){sub 2}(THF){sub n} show when n = 0, the complex exists in an f{sup 2}-{pi}*{sup 4} configuration; whereas an intramolecular electron transfer occurs for n = 1, resulting in an f{sup 3}-{pi}*{sup 3} ground configuration. The magnetic data also indicate that interconversion between the two forms of the complex is possible, limited only by the ability of THF vapor to penetrate the solid on cooling of the sample. Spectroscopic data indicate the complex exists solely in the f{sup 2}-{pi}*{sup 4} form in solution, evidenced by the appearance of only small changes in the electronic absorption spectra of the U(dpp-BIAN){sub 2} complex on titration with THF and by measurement of the solution magnetic moment m d{sub 8}-tetrahydrofuran using Evans method. Electrochemistry of the complexes is reported, with small differences observed in wave potentials between metals and in the presence of THF. These data represent the first example of a well-defined, reversible intramolecular electron transfer in an f-element complex and the second example of oxidation state change through dative interaction with a metal ion.

  2. Evaluation Of Water Quality At River Bian In Merauke Papua

    Science.gov (United States)

    Djaja, Irba; Purwanto, P.; Sunoko, H. R.

    2018-02-01

    River Bian in Merauke Regency has been utilized by local people in Papua (the Marind) who live along the river for fulfilling their daily needs, such as shower, cloth and dish washing, and even defecation, waste disposal, including domestic waste, as well as for ceremonial activities related to the locally traditional culture. Change in land use for other necessities and domestic activities of the local people have mounted pressures on the status of the River Bian, thus decreasing the quality of the river. This study had objectives to find out and to analyze river water quality and water quality status of the River Bian, and its compliance with water quality standards for ideal use. The study determined sample point by a purposive sampling method, taking the water samples with a grab method. The analysis of the water quality was performed by standard and pollution index methods. The study revealed that the water quality of River Bian, concerning BOD, at the station 3 had exceeded quality threshold. COD parameter for all stations had exceeded the quality threshold for class III. At three stations, there was a decreasing value due to increasing PI, as found at the stations 1, 2, and 3. In other words, River Bian had been lightly contaminated.

  3. Evaluation Of Water Quality At River Bian In Merauke Papua

    Directory of Open Access Journals (Sweden)

    Djaja Irba

    2018-01-01

    Full Text Available River Bian in Merauke Regency has been utilized by local people in Papua (the Marind who live along the river for fulfilling their daily needs, such as shower, cloth and dish washing, and even defecation, waste disposal, including domestic waste, as well as for ceremonial activities related to the locally traditional culture. Change in land use for other necessities and domestic activities of the local people have mounted pressures on the status of the River Bian, thus decreasing the quality of the river. This study had objectives to find out and to analyze river water quality and water quality status of the River Bian, and its compliance with water quality standards for ideal use. The study determined sample point by a purposive sampling method, taking the water samples with a grab method. The analysis of the water quality was performed by standard and pollution index methods. The study revealed that the water quality of River Bian, concerning BOD, at the station 3 had exceeded quality threshold. COD parameter for all stations had exceeded the quality threshold for class III. At three stations, there was a decreasing value due to increasing PI, as found at the stations 1, 2, and 3. In other words, River Bian had been lightly contaminated.

  4. Application thinking on Bian-stone of the acousto-optic effect in the treatment of primary dysmenorrhea

    Science.gov (United States)

    Ge, Shu; Chen, Gui-Zhen; Liu, Song-Hao

    2009-08-01

    In order to identify the relations between the Si-Bin Bian-stone of the mineral composition characteristics and Bian-stone of the good infrared emission features. A detailed study of the Sibin Bian-stone samples was conducted by using the laser Raman spectroscopy and high-resolution transmission electron microscopy (HRTEM). The study is to provide theoretical physical support for Bian-stone in the treatment of primary dysmenorrhea. And Thermal tomography technology (TTM) is intended to be carried out to assess the effects of Bian-stone. The Raman spectroscopic study confirmed the existence of fine-grained pyrite, anatase, calcitepyrite and graphite. It is believed that the combination of good thermal properties of the above 4 minerals make the Sibin Bian-stone as a useful material with very good physiotherapical functions. The ultrasonic has a resonance with the body's biological molecules so that it can improve meridians microcirculation. Hence, the Sibin Bian-stones can be used to make acupuncture tools for stimulating the circulation of the blood in vessels and relieving pains of human beings by utilizing its infrared thermal radiation property. TTM which accepts the heat produced by the metabolism process of life can reflect the energy status information, TTM will be introduced to evaluate effect at the overall level of the abdomen from the thermal image and analyze to derive a comprehensive diagnosis. In sum, this experiment is explored to provide a new idea for the modernization of traditional Chinese medicine.

  5. Biological Screening of Newly Synthesized BIAN N-Heterocyclic Gold Carbene Complexes in Zebrafish Embryos

    Science.gov (United States)

    Farooq, Muhammad; Abu Taha, Nael; Butorac, Rachel R.; Evans, Daniel Anthony; Elzatahry, Ahmed A.; Elsayed, Elsayed Ahmed; Wadaan, Mohammad A. M.; Al-Deyab, Salem S.; Cowley, Alan H.

    2015-01-01

    N-Heterocyclic carbene (NHC) metal complexes possess diverse biological activities but have yet to be extensively explored as potential chemotherapeutic agents. We have previously reported the synthesis of a new class of NHC metal complexes N-heterocyclic with acetate [IPr(BIAN)AuOAc] and chloride [IPr(BIAN)AuCl] ligands. In the experiments reported herein, the zebrafish embryos were exposed to serial dilutions of each of these complexes for 10–12 h. One hundred percent mortality was observed at concentrations ≥50 µM. At sub-lethal concentrations (10–30 µM), both compounds influenced zebrafish embryonic development. However, quite diverse categories of abnormalities were found in exposed embryos with each compound. Severe brain deformation and notochord degeneration were evident in the case of [IPr(BIAN)AuOAc]. The zebrafish embryos treated with [IPr(BIAN)AuCl] exhibited stunted growth and consequently had smaller body sizes. A depletion of 30%–40% glutathione was detected in the treated embryos, which could account for one of the possible mechanism of neurotoxicity. The fact that these compounds are capable of both affecting the growth and also compromising antioxidant systems by elevating intracellular ROS production implies that they could play an important role as a new breed of therapeutic molecules. PMID:26501273

  6. Changrong Zhou

    Indian Academy of Sciences (India)

    Correlation between temperature-dependent permittivity dispersion and depolarization behaviours in Zr-modified BiFeO3–BaTiO3 piezoelectric ceramics · Weidong Zeng Changrong Zhou Jianrong Xiao Jiafeng Ma · More Details Abstract Fulltext PDF. The correlation between permittivity frequency dispersion and depoling ...

  7. Polymorphism in exons of the myostatin gene and its relationship with body weight traits in the Bian chicken.

    Science.gov (United States)

    Zhang, Genxi; Ding, Fuxiang; Wang, Jinyu; Dai, Guojun; Xie, Kaizhou; Zhang, Lijun; Wang, Wei; Zhou, Shenghua

    2011-02-01

    In our research, single nucleotide polymorphisms (SNPs) of exon regions of the myostatin gene were detected by PCR-SSCP in the Bian chicken and three reference chicken populations (Jinghai, Youxi, and Arbor Acre). Four novel SNPs (G2283A, C7552T, C7638T, and T7661A) were detected. The findings from the least square means showed that Bian chickens with EE and DE genotypes had significantly higher body weight, at 6-18 weeks of age, than those of the DD genotype (P chicken.

  8. Zhou Enlai and Normalization of Sino-American Relations

    National Research Council Canada - National Science Library

    O'Brien, D. C

    1995-01-01

    .... Inflating Zhou's image as one of the truly great statesman of our time, after all, serves equally well to polish Kissinger's professional halo as a practitioner of statecraft of heroic proportions...

  9. Polymorphisms of the myostatin gene and its relationship with reproduction traits in the Bian chicken.

    Science.gov (United States)

    Zhang, Genxi; Zhang, Li; Wei, Yue; Wang, Jinyu; Ding, Fuxiang; Dai, Guojun; Xie, Kaizhou

    2012-01-01

    Myostatin, or growth and differentiation factor 8, is a member of the transforming growth factor-β superfamily; it functions as a negative regulator of skeletal muscle development and growth in mammals. In this study, single nucleotide polymorphisms in the 5' regulatory region and exon 1 of the myostatin gene were detected by PCR-SSCP in the Bian, Jinghai, Youxi, and Arbor Acre chickens, and the associations of the polymorphisms with reproduction traits were analyzed. Seven SNPs (A326G, C334G, C1346T, G1375A, A1473G, G1491A, and G2283A) were found in the myostatin gene. Association analysis showed that the G2283A were significantly associated with reproduction traits. Bian chickens of the GG genotype had a greater age at first egg than those of the GA and AA genotypes (Pchickens of the GA and AA genotypes had larger egg number at 300 days than those of the GG genotype (Pchickens of the AA genotype had significantly higher body weight at 300 days than those of the GG genotype (P<0.05). These results suggested that the myostatin gene may have certain effects on reproduction traits other than merely as a negative regulator of skeletal muscle development and growth in mammals previously reported.

  10. [Comparison of the effects of the intervention with electric thermal bian stone and air suction cup on blood perfusion at meridian points].

    Science.gov (United States)

    Zhao, Pengna; Wang, Yanping; Gu, Feifei; Li, Chaozheng; Wei, Yulong; Wang, Guangjun; Zhang, Weibo

    2018-02-12

    To observe the impacts of the intervention with electric thermal bian stone and air suction cup on blood perfusion (BP) at meridian points and explore the approach of accurate measurement and regulation of meridian qi and blood balance in "precise acupuncture". The laser Doppler line scanner (LDLS) was used to measure BP at bilateral yua n-primary points at the pericardium meridian, the triple energizer meridian, the gallbladder meridian and the liver meridian (small cycle of jueyin to shaoyang meridians) at 31 healthy receptors. The bias ratio of blood perfusion (BPBR) deviated to the reference value was calculated. The electric thermal bian stone and air suction cup were used in the intervention at the he -sea points of the affected meridians in which BPBR was relatively higher at the yuan -primary points. The electric thermal bian stone therapy was used when BPBR was less than -30% and the air suction cupping therapy was used when BPBR was higher than 30%. BP was measured twice before intervention and it was measured separately at the moment after intervention and in 20 min after intervention. The means of BP before and after intervention and the change ratio of blood perfusion (BPCR) before intervention, at the moment after intervention and 20 min after intervention were calculated. 1. After the intervention of electric thermal bian stone, BP mean was increased from (103.51±41.21) PU to (121.97±56.22) PU ( P 0.05), but the change ratio was highly remained. 2. After intervention with air suction cup, BP mean was reduced from (194.83±81.14) PU to (173.88±88.26) PU. Before intervention, at the moment after intervention and 20 min after intervention, separately, BPCR were (7.62±30.49)%, (-12.12±18.20)% and (-14.35±21.25)%. BPCR at the moment after intervention and in 20 min after intervention were significantly different from that before intervention (both P cup is opposite.

  11. The use of AMS radiocarbon dating for Xia-Shang-Zhou chronology

    CERN Document Server

    Guo, Z Y; LiuKeXin; Lu Xiang Yang; Ma Hong Ji; Wu Xiao Hon; Yuan Si Xun

    2000-01-01

    The possibility and problems of using radiocarbon dating to historical chronology are discussed. The current situation of ancient Chinese chronology and the project of Xia-Shang-Zhou chronology are introduced. A chronological study requires the AMS radiocarbon dating with high precision, high reliability and high efficiency. The Peking University AMS facility (PKUAMS) has been upgraded and a series of quality control steps were adopted. To reduce the error of calendar age, wiggle matching with serial samples should be used. Some preliminary results of Xia-Shang-Zhou chronology are presented.

  12. Chaos Control and Synchronization of a Hyperchaotic Zhou System by Integral Sliding Mode control

    Directory of Open Access Journals (Sweden)

    Yashar Toopchi

    2014-12-01

    Full Text Available In this paper, an adaptive integral sliding mode control scheme is proposed for synchronization of hyperchaotic Zhou systems. In the proposed scheme, an integral sliding mode control is designed to stabilize a hyperchaotic Zhou system with known parameters to its unstable equilibrium at the origin. The control is then applied to the synchronization of two identical systems, i.e., a slave and a master hyperchaotic Zhou system with unknown parameters. The adaptive control mechanism introduced synchronizes the systems by estimating the unknown parameters. Simulation results have shown that the proposed method has an excellent convergence from both speed and accuracy points of view, and it outperforms Vaidyanathan’s scheme, which is a well-recognized scheme in this area.

  13. The BIAN ligand 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthene: An electron sponge or a „normal“ alpha-diimine ligand?

    Czech Academy of Sciences Publication Activity Database

    Löw, I.; Bubrin, M.; Paretzki, A.; Fiedler, Jan; Záliš, Stanislav; Kaim, W.

    2017-01-01

    Roč. 455, č. 2 (2017), s. 540-548 ISSN 0020-1693 R&D Projects: GA MŠk LD14129 Grant - others:COST(XE) CM1202 Institutional support: RVO:61388955 Keywords : BIAN diimine ligand * Carbonylmetal complexes * Electron transfer Subject RIV: CG - Electrochemistry OBOR OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis) Impact factor: 2.002, year: 2016

  14. Mapping and validation of a new QTL for adult-plant resistance to powdery mildew in Chinese elite bread wheat line Zhou8425B.

    Science.gov (United States)

    Jia, Aolin; Ren, Yan; Gao, Fengmei; Yin, Guihong; Liu, Jindong; Guo, Lu; Zheng, Jizhou; He, Zhonghu; Xia, Xianchun

    2018-05-01

    Four QTLs for adult-plant resistance to powdery mildew were mapped in the Zhou8425B/Chinese Spring population, and a new QTL on chromosome 3B was validated in 103 wheat cultivars derived from Zhou8425B. Zhou8425B is an elite wheat (Triticum aestivum L.) line widely used as a parent in Chinese wheat breeding programs. Identification of genes for adult-plant resistance (APR) to powdery mildew in Zhou8425B is of high importance for continued controlling the disease. In the current study, the high-density Illumina iSelect 90K single-nucleotide polymorphism (SNP) array was used to map quantitative trait loci (QTL) for APR to powdery mildew in 244 recombinant inbred lines derived from the cross Zhou8425B/Chinese Spring. Inclusive composite interval mapping identified QTL on chromosomes 1B, 3B, 4B, and 7D, designated as QPm.caas-1BL.1, QPm.caas-3BS, QPm.caas-4BL.2, and QPm.caas-7DS, respectively. Resistance alleles at the QPm.caas-1BL.1, QPm.caas-3BS, and QPm.caas-4BL.2 loci were contributed by Zhou8425B, whereas that at QPm.caas-7DS was from Chinese Spring. QPm.caas-3BS, likely to be a new APR gene for powdery mildew resistance, was detected in all four environments. One SNP marker closely linked to QPm.caas-3BS was transferred into a semi-thermal asymmetric reverse PCR (STARP) marker and tested on 103 commercial wheat cultivars derived from Zhou8425B. Cultivars with the resistance allele at the QPm.caas-3BS locus had averaged maximum disease severity reduced by 5.3%. This STARP marker can be used for marker-assisted selection in improvement of the level of powdery mildew resistance in wheat breeding.

  15. Zhou et al., Afr J Tradit Complement Altern Med. (2013) 10(4):175 ...

    African Journals Online (AJOL)

    AJTCAM

    A STUDY OF EXTRACTION PROCESS AND IN VITRO ANTIOXIDANT ACTIVITY OF. TOTAL PHENOLS FROM RHIZOMA IMPERATAE. Xian-rong Zhou* ..... Progress of Research on In Vitro Antioxidant Function Evaluation Methods,Meat Research, 11: 41-46. 4. Lai Wah Chan, Emily LC Cheah, Constance LL Saw, Wanyu ...

  16. Juan Cham-Bom-Bian: recorrido del "médico chino"desde la Habana hacia Cárdenas. Breves apuntes históricos

    OpenAIRE

    Vega Jiménez, Junior

    2015-01-01

    Los orígenes de la medicina tradicional china en Cuba datan de la época colonial, cuyas técnicasfueronintroducidas a través de los inmigrantes chinos. Es muy frecuentelautilización, tanto en el argot popular como médico,delrefrán: "A ese no lo cura ni el médico chino".El origen de esta frase es real, y proviene del poco conocido JuanCham-Bom-Bian. La mayor parte de su estancia en Cuba ocurrió entre la sciudades de La Habana y Cárdenas; enesta última ocurrió su misteriosa muerte. El objetivo d...

  17. On personality traits of Zhou En-lai%浅谈周恩来的人格特质

    Institute of Scientific and Technical Information of China (English)

    赵世成

    2013-01-01

    Zhou En-lai's personality traits, embodied not only the traditional virtues of the Chinese people, but also embodies the Chinese Communists excellent quality. Inherit and carry forward the great spirit of personality of Zhou En-lai, are great practical significance to comprehensively improve the quality of spiritual culture and the construction of harmonious society.%周恩来的人格特质,既是中华民族传统美德的具体体现,也是中国共产党人优秀品质的具体体现。继承和发扬周恩来伟大的人格精神,对于全面提高精神文化素质和构建和谐社会都有重大的现实意义。

  18. Shifting diets and the rise of male-biased inequality on the Central Plains of China during Eastern Zhou.

    Science.gov (United States)

    Dong, Yu; Morgan, Chelsea; Chinenov, Yurii; Zhou, Ligang; Fan, Wenquan; Ma, Xiaolin; Pechenkina, Kate

    2017-01-31

    Farming domesticated millets, tending pigs, and hunting constituted the core of human subsistence strategies during Neolithic Yangshao (5000-2900 BC). Introduction of wheat and barley as well as the addition of domesticated herbivores during the Late Neolithic (∼2600-1900 BC) led to restructuring of ancient Chinese subsistence strategies. This study documents a dietary shift from indigenous millets to the newly introduced cereals in northcentral China during the Bronze Age Eastern Zhou Dynasty (771-221 BC) based on stable isotope analysis of human and animal bone samples. Our results show that this change affected females to a greater degree than males. We find that consumption of the newly introduced cereals was associated with less consumption of animal products and a higher rate of skeletal stress markers among females. We hypothesized that the observed separation of dietary signatures between males and females marks the rise of male-biased inequality in early China. We test this hypothesis by comparing Eastern Zhou human skeletal data with those from Neolithic Yangshao archaeological contexts. We find no evidence of male-female inequality in early farming communities. The presence of male-biased inequality in Eastern Zhou society is supported by increased body height difference between the sexes as well as the greater wealth of male burials.

  19. Chinese Dream——Concert in Commemoration of 115th Birth Anniversary of Premier Zhou Enlai Held

    Institute of Scientific and Technical Information of China (English)

    Our; Staff; Reporter

    2013-01-01

    <正>The theme song of the film The Founding of a Republic sung by male vocalists Dai Yuqiang and Wei Song reverberated in the Opera Hall at the National Center for the Performing Arts on the `evening of March 14. It marked the start of the concert in commemoration of the 115th anniversary of the birth of Premier Zhou Enlai, with "Chinese Dream" as the theme.

  20. XANES investigation of Chinese faience excavated from Peng State Cemetery site in Western Zhou Period (BC1046–BC771)

    International Nuclear Information System (INIS)

    Hao, Wentao; Yang, Yimin; Zhu, Jian; Gu, Zhou; Xie, Yaoting; Zhang, Jing; Wang, Lihua

    2014-01-01

    Highlights: • We analyzed faience of Peng State archaeological cemetery site in Western Zhou Dynasty (BC1046–BC771). • We investigated the chemical composition and oxidation state by energy dispersive X-ray fluorescence (EDXRF) and X-ray absorption near edge spectroscopy (XANES), respectively. • The coloring element in both beads is copper in +2 valence, and the color divergence of these two beads may originate from different local chemical environments of Cu 2+ . • Chinese faience in this period is the earliest glaze with copper colorant. - Abstract: As a special kind of glazed ceramic, faience has an important role to play in the technological trajectory that eventually leads to the development of ancient glass. In China, faience products first emerged in early Western Zhou Dynasty (1046BC–771BC), and their great significance as well as brilliant colors varying between blue and green attracted a lot of scholars. However, scientific researches on the color source of Chinese faience in view of microstructure characterization are quite few. In the present work, analyses by energy dispersive X-ray fluorescence (EDXRF) and X-ray absorption near edge spectroscopy (XANES) were carried out on two faience beads with relatively blue and green color, respectively, both of which were excavated from Peng State archaeological cemetery site in Western Zhou Dynasty. The results show that the coloring element in both beads is copper with +2 valence, and the color divergence of these two beads may originate from different local chemical environments of Cu 2+ . It is suggested that the faience in this period is the earliest glaze with copper colorant in China

  1. XANES investigation of Chinese faience excavated from Peng State Cemetery site in Western Zhou Period (BC1046–BC771)

    Energy Technology Data Exchange (ETDEWEB)

    Hao, Wentao; Yang, Yimin [Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044 (China); Department of Scientific History and Archaeometry, University of Chinese Academy of Sciences, Beijing 100049 (China); Zhu, Jian, E-mail: jzhu@ucas.ac.cn [Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044 (China); Department of Scientific History and Archaeometry, University of Chinese Academy of Sciences, Beijing 100049 (China); Gu, Zhou [Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044 (China); Department of Scientific History and Archaeometry, University of Chinese Academy of Sciences, Beijing 100049 (China); Xie, Yaoting [Institute of Archaeology of Shanxi Province, Taiyuan 030001 (China); Zhang, Jing [Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); Wang, Lihua [Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201204 (China)

    2014-10-15

    Highlights: • We analyzed faience of Peng State archaeological cemetery site in Western Zhou Dynasty (BC1046–BC771). • We investigated the chemical composition and oxidation state by energy dispersive X-ray fluorescence (EDXRF) and X-ray absorption near edge spectroscopy (XANES), respectively. • The coloring element in both beads is copper in +2 valence, and the color divergence of these two beads may originate from different local chemical environments of Cu{sup 2+}. • Chinese faience in this period is the earliest glaze with copper colorant. - Abstract: As a special kind of glazed ceramic, faience has an important role to play in the technological trajectory that eventually leads to the development of ancient glass. In China, faience products first emerged in early Western Zhou Dynasty (1046BC–771BC), and their great significance as well as brilliant colors varying between blue and green attracted a lot of scholars. However, scientific researches on the color source of Chinese faience in view of microstructure characterization are quite few. In the present work, analyses by energy dispersive X-ray fluorescence (EDXRF) and X-ray absorption near edge spectroscopy (XANES) were carried out on two faience beads with relatively blue and green color, respectively, both of which were excavated from Peng State archaeological cemetery site in Western Zhou Dynasty. The results show that the coloring element in both beads is copper with +2 valence, and the color divergence of these two beads may originate from different local chemical environments of Cu{sup 2+}. It is suggested that the faience in this period is the earliest glaze with copper colorant in China.

  2. Digallane with redox-active diimine ligand: dualism of electron-transfer reactions.

    Science.gov (United States)

    Fedushkin, Igor L; Skatova, Alexandra A; Dodonov, Vladimir A; Chudakova, Valentina A; Bazyakina, Natalia L; Piskunov, Alexander V; Demeshko, Serhiy V; Fukin, Georgy K

    2014-05-19

    The reactivity of digallane (dpp-Bian)Ga-Ga(dpp-Bian) (1), which consists of redox-active ligand 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthene (dpp-Bian), has been studied. The reaction of 1 with I2 proceeds via one-electron oxidation of each of two dpp-Bian ligands to a radical-anionic state and affords complex (dpp-Bian)IGa-GaI(dpp-Bian) (2). Dissolution of complex 2 in pyridine (Py) gives monomeric compound (dpp-Bian)GaI(Py) (3) as a result of a solvent-induced intramolecular electron transfer from the metal-metal bond to the dpp-Bian ligands. Treatment of compound 3 with B(C6F5)3 leads to removal of pyridine and restores compound 2. The reaction of compound 1 with 3,6-di-tert-butyl-ortho-benzoquinone (3,6-Q) proceeds with oxidation of all the redox-active centers in 1 (the Ga-Ga bond and two dpp-Bian dianions) and results in mononuclear catecholate (dpp-Bian)Ga(Cat) (4) (Cat = [3,6-Q](2-)). Treatment of 4 with AgBF4 gives a mixture of [(dpp-Bian)2Ag][BF4] (5) and (dpp-Bian)GaF(Cat) (6), which both consist of neutral dpp-Bian ligands. The reduction of benzylideneacetone (BA) with 1 generates the BA radical-anions, which dimerize, affording (dpp-Bian)Ga-(BA-BA)-Ga(dpp-Bian) (7). In this case the Ga-Ga bond remains unchanged. Within 10 min at 95 °C in solution compound 7 undergoes transformation to paramagnetic complex (dpp-Bian)Ga(BA-BA) (8) and metal-free compound C36H40N2 (9). The latter is a product of intramolecular addition of the C-H bond of one of the iPr groups to the C═N bond in dpp-Bian. Diamagnetic compounds 3, 5, 6, and 9 have been characterized by NMR spectroscopy, and paramagnetic complexes 2, 4, 7, and 8 by ESR spectroscopy. Molecular structures of 2-7 and 9 have been established by single-crystal X-ray analysis.

  3. QTL Mapping of Adult-Plant Resistance to Leaf Rust in the Wheat Cross Zhou 8425B/Chinese Spring Using High-Density SNP Markers

    Directory of Open Access Journals (Sweden)

    Peipei Zhang

    2017-05-01

    Full Text Available Wheat leaf rust is an important disease worldwide. Growing resistant cultivars is an effective means to control the disease. In the present study, 244 recombinant inbred lines from Zhou 8425B/Chinese Spring cross were phenotyped for leaf rust severities during the 2011–2012, 2012–2013, 2013–2014, and 2014–2015 cropping seasons at Baoding, Hebei province, and 2012–2013 and 2013–2014 cropping seasons in Zhoukou, Henan province. The population was genotyped using the high-density Illumina iSelect 90K SNP assay and SSR markers. Inclusive composite interval mapping identified eight QTL, designated as QLr.hebau-2AL, QLr.hebau-2BS, QLr.hebau-3A, QLr.hebau-3BS, QLr.hebau-4AL, QLr.hebau-4B, QLr.hebau-5BL, and QLr.hebau-7DS, respectively. QLr.hebau-2BS, QLr.hebau-3A, QLr.hebau-3BS, and QLr.hebau-5BL were derived from Zhou 8425B, whereas the other four were from Chinese Spring. Three stable QTL on chromosomes 2BS, 4B and 7DS explained 7.5–10.6%, 5.5–24.4%, and 11.2–20.9% of the phenotypic variance, respectively. QLr.hebau-2BS in Zhou 8425B might be the same as LrZH22 in Zhoumai 22; QLr.hebau-4B might be the residual resistance of Lr12, and QLr.hebau-7DS is Lr34. QLr.hebau-2AL, QLr.hebau-3BS, QLr.hebau-4AL, and QLr.hebau-5BL are likely to be novel QTL for leaf rust. These QTL and their closely linked SNP and SSR markers can be used for fine mapping, candidate gene discovery, and marker-assisted selection in wheat breeding.

  4. Bian Zheng Lun Zhi as a Complementary and Alternative Treatment for Menstrual Cramps in Women with Dysmenorrhea: A Prospective Clinical Observation

    Directory of Open Access Journals (Sweden)

    Pin-Yi Lin

    2014-01-01

    Full Text Available Background. Limited scientific evidence supports the positive effects of traditional Chinese medicine (TCM for treating dysmenorrhea. Thus, an observation period of 3 months could verify the ancient indication that TCM treatments effectively alleviate menstrual cramps in women with primary dysmenorrhea or endometriosis. Methods. A prospective, nonrandomized study (primary dysmenorrhea and endometriosis groups was conducted in women with dysmenorrhea for more than three consecutive menstrual cycles. All patients received TCM prescriptions based on bian zheng lun zhi theory 14 days before menstruation for a period of 12 weeks. Pain intensity was evaluated using a 10-cm visual analogue scale and two validated questionnaires (the Menstrual Distress Questionnaire and the World Health Organization Quality of Life questionnaire. Results. Of the initial 70 intent-to-treat participants, the women with dysmenorrhea reported significant alleviation of cramps during menstruation after the 12-week TCM treatment. Mixed model analysis revealed that TCM prescriptions were more effective in alleviating fatigue, hot flashes, dizziness, painful breasts, excitement, and irritability in the primary dysmenorrhea group (N=36 than in the endometriosis group (N=34. Conclusion. TCM prescriptions based on syndrome differentiation theory might be a potentially viable choice for treating painful menstruation and premenstrual symptoms after ruling out endometriosis.

  5. Remote Sensing of Hydrological Changes in Tian-e-Zhou Oxbow Lake, an Ungauged Area of the Yangtze River Basin

    Directory of Open Access Journals (Sweden)

    Chao Yang

    2017-12-01

    Full Text Available The hydrological pattern changes have a great influence on the wetland environment. However, some important wetland areas often lack historical observations due to economic and physical conditions. The Tian-e-Zhou oxbow lake wetland is an important habitat for two endangered species and also has very little historical hydrological data. Remote sensing images can be used to explore the historical water area fluctuation of lakes. In addition, remote sensing can also be used to obtain historical water levels based on the water boundary elevation integrated with a topographic data (WBET method or the level-surface area relationship curve (LRC method. In order to minimize the uncertainty of the derived results, both methods were introduced in the extraction of the water level of Tian-e-Zhou during 1992–2015. The results reveal that the hydrological regime of the oxbow lake has experienced a significant change after the Shatanzi Levee construction in 1998. With the impact of the levee, the mean annual water surface area of the lake was reduced by 5.8 km2 during the flood season, but, during the non-flood season, it was increased by 1.35 km2. For the same period, the water level of the lake during the flood season also showed a 1.47 m (WBET method or 3.21 m (LRC method decrease. The mean annual water level increased by 1.12 m (WBET method or 0.75 m (LRC method. Both results had a good accuracy with RMSE (root-mean-square errors of less than 0.4 m. Furthermore, the water level differences between the Yangtze River channel and the oxbow lake increased by at least 0.5 m. It is found that the hydrological pattern of the oxbow lake changed significantly after the levee construction, which could bring some disadvantages to the habitats of the two endangered species.

  6. 周恩来的柔性人格从何而来%Where w as Zhou Enlai's Soft Personality from ?

    Institute of Scientific and Technical Information of China (English)

    谷传华

    2015-01-01

    周恩来的人格结构刚柔相济、严而有情,既有适应职业要求的“刚性”的一面,又有“柔性”的一面。周恩来的柔性人格从何而来?心理传记学分析显示,它很可能是由早年母爱的温暖、亲朋好友的影响等家庭因素促成的。周恩来具有对家的深切的依恋,而儿童青少年时期得到的家庭温暖和关爱是这种依恋形成的基础。在此过程中,母亲式人物特别是作为周恩来依恋对象的养母很可能发挥了至关重要的影响,促成了他的一系列的人格特征。%Zhou Enlai's personality was composed of “hard” and “soft” traits . On one hand , he had the“hard” traits ,which satisfied the need of politics .On the other hand ,he had the “soft” traits .Where was his soft personality from? Psycho‐biographical analysis indicated that maternal love and family members' and peers' influence had probably contributed to the development of Zhou Enlai's soft personality traits . He might develop the deep attachment to his family , which was based on the warmth and love from the family in his childhood and adolescence . In the process , mother‐like people played a significant role in the development of his soft personality traits .

  7. 76 FR 51940 - Administrative Review of Certain Frozen Warmwater Shrimp From the People's Republic of China...

    Science.gov (United States)

    2011-08-19

    ... Central Records Unit (``CRU''), Main Commerce Building, Room 7046, and is accessible on the Department's....; Hai Li Aquatic Co., Ltd.; Hainan Hailisheng Food Co., Ltd.; Hainan Seaberry Seafoods; Hainan Siyuan...

  8. The role and significance of Luo Zhiyuan's Shu yi hui bian in the history of plague in Lingnan (south of the five ridges).

    Science.gov (United States)

    Li, H; Lai, W

    1999-04-01

    Being the earliest monograph on plague in China, Luo Zhiyuan's Shu yi hui bian, not included in the National Catalogue of TCM Books, include the following contents: personal idea on the etiology of plague; Luo's friend Wu Xuanchang' unpublished Shu yu zhi fa on the treatment and manifestations of plague; Luo's specific recipe for plague based on medified Wang Qingren's Jie du huo xue decoction based on Wang Qingrens yi lin gai cuo; therapy for critical cases; many therapies applied on Lingnan, including experimental recipes, external therapy, preventive methods, and preventing recurrence methods; Luo's special administrating methods, including persisting day-and-night method, immediate persisting method, single-dose persisting method, and double-dose persisting method. He also gave several cured case records. His book, featuring unique idea with good effect, was repeatedly printed and extensively distributed, exerting influence, more or less, on the plague monographs of later ages, and occupying important position in the history of plague on Lingnan and the whole country as well. His idea of "that poisons and static blood" in pathogenesis and therapeutic principle of antitoxicity and activating blood is coincided with the results of present day clinical and laboratory studies. His administration of medicines is heuristic to the therapy of critical cases with Chinese medicaments and to the recognition of pathogenesis, etiology, and treatment of modern plague as well as other diseases of similar etiology and pathognesis and is worth of further study.

  9. 高校宿舍文化建设初探——以西安思源学院“我爱我家”宿舍形象设计大赛为例%On College Dormitory Culture Construction——Take Xi'an Siyuan University "I love My Home" Dormitory Image Design Competition for example

    Institute of Scientific and Technical Information of China (English)

    刘义华

    2012-01-01

    The student dormitory is an important site of college students. University in the full implementation of the logis- tics service, the two education plays an important role in the dormitory management, service and educational functions of the high school students, dormitory management in the implementation of full educating people, the entire process of edu- cating people, education for all-round education, irreplaceable important position. The article takes Xi'an Siyuan College as an example, discussed the building of the dormitory culture.%学生宿舍是高校大学生活动的重要场所。目前高校在全面落实后勤“三服务、两育人”中学生宿舍的管理、服务和教育功能中占有重要地位,宿舍管理在落实全员育人、全程育人、全方位育人的教育工作中,有着不可替代的重要位置。文章以西安思源学院为例,探讨了高校宿舍文化的建设。

  10. The Integration of Chuji Calendars in the Late Western Zhou Dynasty

    Science.gov (United States)

    Li, Y.

    2017-03-01

    In this paper, we investigate 23 four-element-materials contained Chuji (characters usually on bronze vessels, perhaps represent the moon phase) in the late Western Zhou Dynasty. It is assumed that all 5 elder-year data (kings' year>25 yr) should belong to the periods of king Li or king Xuan. At the same time, in order to guarantee the completeness, compatibility, and objectivity of these kinds of calendars, in the paper we build up them respectively according to the 24 characters of Chinese ancient calendar. We use the transformation platform for Chinese ancient dates to finish the calendars, consider the five different first years when both kings took their powers, set the moon age of Chuji cover any day in a lunar month, and as far as possible give every result for each material as in different kings' period. As a result, we totally derive 13 calendars according to different combinations of the characters of ancient calendars. When subdivided by the different combinations of the kings' periods, 33 solutions are obtained, but the moon phases of Chuji are usually in the second half month. The best result, with Jian Mao and the leap month in the end of the year, is related with the BC878 (BC827) as the first year of king Li (king Xuan). The coincidence rate of 23 data is 100%, and average moon phases are 19.84 days. The suboptimum choices have four solutions; the coincidence rate is 95.7%, respectively with Jian Chen and the leap month in the middle of the year; together with Jian Wu and the leap month in the middle or end of the year. We point out that these results may constitute and link respectively with other materials (even with other moon phases) as long as have the same calendar features. After adopting more materials and higher qualification, the scope of the solutions can be further limited and narrow. In addition, the different researchers can easily obtain or intercept their needed results respectively from this paper.

  11. On sound transmission through double-walled cylindrical shells lined with poroelastic material: Comparison with Zhou's results and further effect of external mean flow

    Science.gov (United States)

    Liu, Yu; He, Chuanbo

    2015-12-01

    In this discussion, the corrections to the errors found in the derivations and the numerical code of a recent analytical study (Zhou et al. Journal of Sound and Vibration 333 (7) (2014) 1972-1990) on sound transmission through double-walled cylindrical shells lined with poroelastic material are presented and discussed, as well as the further effect of the external mean flow on the transmission loss. After applying the corrections, the locations of the characteristic frequencies of thin shells remain unchanged, as well as the TL results above the ring frequency where BU and UU remain the best configurations in sound insulation performance. In the low-frequency region below the ring frequency, however, the corrections attenuate the TL amplitude significantly for BU and UU, and hence the BB configuration exhibits the best performance which is consistent with previous observations for flat sandwich panels.

  12. Investigations of Tissue-Level Mechanisms of Primary Blast Injury Through Modeling, Simulation, Neuroimaging and Neuropathological Studies

    Science.gov (United States)

    2012-07-10

    2007;25(1):97-98. [19] Stewart C. Blast Injuries. Colorado Springs: USAF Academy Hospital; 2006. 88 p. [20] Cernak I, Wang Z, Jiang J, Bian X, Savic J...Wang Z, Jiang J, Bian X, Savic J. Ultrastructural and Functional Characteristics of Blast Injury- Induced Neurotrauma. Journal of Trauma: Injury

  13. Thermoelectric cooler concepts and the limit for maximum cooling

    International Nuclear Information System (INIS)

    Seifert, W; Hinsche, N F; Pluschke, V

    2014-01-01

    The conventional analysis of a Peltier cooler approximates the material properties as independent of temperature using a constant properties model (CPM). Alternative concepts have been published by Bian and Shakouri (2006 Appl. Phys. Lett. 89 212101), Bian (et al 2007 Phys. Rev. B 75 245208) and Snyder et al (2012 Phys. Rev. B 86 045202). While Snyder's Thomson cooler concept results from a consideration of compatibility, the method of Bian et al focuses on the redistribution of heat. Thus, both approaches are based on different principles. In this paper we compare the new concepts to CPM and we reconsider the limit for maximum cooling. The results provide a new perspective on maximum cooling. (paper)

  14. The family name Solimonadaceae Losey et al. 2013 is illegitimate, proposals to create the names 'Sinobacter soli' comb. nov. and 'Sinobacter variicoloris' contravene the Code, the family name Xanthomonadaceae Saddler and Bradbury 2005 and the order name Xanthomonadales Saddler and Bradbury 2005 are illegitimate and notes on the application of the family names Solibacteraceae Zhou et al. 2008, Nevskiaceae Henrici and Johnson 1935 (Approved Lists 1980) and Lysobacteraceae Christensen and Cook 1978 (Approved Lists 1980) and order name Lysobacteriales Christensen and Cook 1978 (Approved Lists 1980) with respect to the classification of the corresponding type genera Solibacter Zhou et al. 2008, Nevskia Famintzin 1892 (Approved Lists 1980) and Lysobacter Christensen and Cook 1978 (Approved Lists 1980) and importance of accurately expressing the link between a taxonomic name, its authors and the corresponding description/circumscription/emendation.

    Science.gov (United States)

    Tindall, B J

    2014-01-01

    In a recent publication the name Solimonadaceae Losey et al. 2013 has been proposed as a replacement name for the family name Sinobacteraceae Zhou et al. 2008. This course of action contravenes the current Code governing the nomenclature of prokaryotes, making Solimonadaceae Losey et al. 2013 an illegitimate name that neither has claim to priority nor can be used as a correct name. Closer examination of publications dealing with the taxonomy of members of the genera Solimonas and Sinobacter and the placement of these taxa at the rank of family and order reveal problems associated with the application of the family names Sinobacteraceae Zhou et al. 2008, Nevskiaceae Henrici and Johnson 1935 (Approved Lists 1980) and Lysobacteraceae Christensen and Cook 1978 (Approved Lists 1980) and the order names Lysobacterales Christensen and Cook 1978 (Approved Lists 1980) and Xanthomonadales Saddler and Bradbury 2005.

  15. On ZHOU Xicheng and the Modern Education in Guizhou%周西成与贵州近代教育探析

    Institute of Scientific and Technical Information of China (English)

    李懋君

    2012-01-01

    Due to the geographical position of Guizhou, its education was in backward state. The period of the Republic of China saw the tangled warfare of warlords and the destitute life of the people. Zhou Xicheng advocated the modernization of Guizhou education reform during his governance, including reorganizing educational administrative organizations, expanding schools and appointing celebrities to improve schools environment, recruiting excellent teachers and setting up Guizhou University, the above measures gained great reputation for Guizhou in the southwest region. These measures played a positive role on the modernization of Guizhou education and improved the education modernization in Guizhou.%贵州由于地理位置原因,文化教育一直处于落后状态。民国时期,军阀混战,民不聊生。周西成主政时期对贵州教育进行近代化改革,他整顿教育行政机关、扩建中小学、任用知名人士改善学校境况、扩充优良师资和创办贵州大学等,这些措施使贵州在西南地区一时名声大噪。以上各项措施对贵州教育近代化的影响起到了积极作用,以此推动了贵州教育近代化的发展。

  16. Graphene energy storage and conversion applications

    CERN Document Server

    Liu, Zhaoping

    2014-01-01

    Series PrefacePrefaceAuthorsGraphene Overview; Xufeng Zhou, Wei Wang, and Zhaoping LiuSynthesis of Graphene; Wei Wang, Hailiang Cao, Xufeng Zhou, and Zhaoping LiuApplications of Graphene in Lithium Ion Batteries; Xufeng Zhou and Zhaoping LiuApplications of Graphene in New-Concept Batteries; Xufeng Zhou and Zhaoping LiuApplications of Graphene in Supercapacitors; Chao Zheng, Xufeng Zhou, Hailiang Cao, and Zhaoping LiuApplications of Graphene in Solar Cells; Fuqiang Huang, Dongyun Wan, Hui Bi, and Tianquan LinApplications of Graphene in Fuel Cells; Xuejun Zhou, Jinli Qiao, and Yuyu LiuIndex.

  17. Catalyst activity or stability: the dilemma in Pd-catalyzed polyketone synthesis.

    Science.gov (United States)

    Amoroso, Francesco; Zangrando, Ennio; Carfagna, Carla; Müller, Christian; Vogt, Dieter; Hagar, Mohamed; Ragaini, Fabio; Milani, Barbara

    2013-10-28

    A series of Pd-complexes containing nonsymmetrical bis(aryl-imino)acenaphthene (Ar-BIAN) ligands, characterized by substituents on the meta positions of the aryl rings, have been synthesized, characterized and applied in CO/vinyl arene copolymerization reactions. Crystal structures of two neutral Pd-complexes have been solved allowing comparison of the bonding properties of the ligand. Kinetic and mechanistic investigations on these complexes have been performed. The kinetic investigations indicate that in general ligands with electron-withdrawing substituents give more active, but less stable, catalytic systems, although steric effects also play a role. The good performance observed with nonsymmetrical ligands is at least in part due to a compromise between catalyst activity and lifetime, leading to a higher overall productivity with respect to catalysts based on their symmetrical counterparts. Additionally, careful analysis of the reaction profiles provided information on the catalyst deactivation pathway. The latter begins with the reduction of a Pd(II) Ar-BIAN complex to the corresponding Pd(0) species, a reaction that can be reverted by the action of benzoquinone. Then the ligand is lost, a process that appears to be facilitated by the contemporary coordination of an olefin or a CO molecule. The so formed Pd(0) complex immediately reacts with another molecule of the initial Pd(II) complex to give a Pd(I) dimeric species that irreversibly evolves to metallic palladium. Mechanistic investigations performed on the complex with a nonsymmetrical Ar-BIAN probe evidence that the detected intermediates are characterized by the Pd-C bond trans to the Pd-N bond of the aryl ring bearing electron-withdrawing substituents. In addition, the intermediate resulting from the insertion of 4-methylstyrene into the Pd-acyl bond is a five-member palladacycle and not the open-chain η(3)-allylic species observed for complexes with Ar-BIANs substituted in ortho position.

  18. [Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

    Science.gov (United States)

    Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

    2014-01-01

    Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

  19. 75 FR 18076 - Changes in Flood Elevation Determinations

    Science.gov (United States)

    2010-04-09

    ...; Chairman, Coconino (08-09-1418P). Arizona Daily Sun. County Board of Supervisors, 219 East Cherry Avenue... February 13, 2009; The Honorable Paul Biane, June 19, 2009 060270 No: B-1044). of San Bernardino February...

  20. SUBJECT INDEX

    Indian Academy of Sciences (India)

    R.Narasimhan(krishtel emaging)1461 1996 Oct 15 13:05:22

    bian Pacific Ocean and its relationship with the wind field using .... Electron spin resonance dating of fault gouge from ... impact. Assimilation of IRS-P4 (MSMR) meteorological data in the NCMRWF global data ... mobile auroral current systems.

  1. Marine Chemistry in the People’s Republic of China.

    Science.gov (United States)

    1984-08-01

    organisms LANG Chinese 265 AUTH Wang, Lizhi; Zhang, Xiaoping; Li, Dexin; Zhou, Mingyu AFFI Institute of Atmospheric Physics, Academia Sinica DATE 1983...their transportation trends at the east margin of Lai Zhou Bay Zhou, Mingyu )A e ’: . 265 Preliminary study on the vertical distribution of atmospheric

  2. upstream region of the myostatin gene in four chicken breeds and its

    African Journals Online (AJOL)

    user

    2012-05-17

    May 17, 2012 ... processing site and a carboxy-terminal region containing nine cysteines ... cultivated meat breed (minitype) and the Youxi chicken is a local breed raised for ..... Allele R was the additive gene on growth traits. Bian chickens ...

  3. (dust, PM10 , and BC) using CHIMERE chemistry tra

    Indian Academy of Sciences (India)

    The objective of this study is to evaluate the ability of a European chemistry transport model,. 'CHIMERE' driven by ..... tive days in May 2008 (12–16 May) to simulate the dust storm ...... Regional Office for Europe, Copenhagen. Zender C, Bian ...

  4. Three new species of the genus Gnamptogenys (Hymenoptera, Formicidae from southern China with a key to the known Chinese species

    Directory of Open Access Journals (Sweden)

    Zhilin Chen

    2017-02-01

    Full Text Available Three new species of the genus Gnamptogenys Roger, 1863 are described from southern China: Gnamptogenys dentihumera Chen, Lattke & Zhou, sp. n., Gnamptogenys nanlingensis Chen, Lattke & Zhou, sp. n. and Gnamptogenys quadrutinodules Chen, Lattke & Zhou, sp. n. A distribution map and an identification key to workers for the known species of China are provided.

  5. Retracted: Effects of pro-inflammatory cytokines on mineralization potential of rat dental pulp stem cells

    NARCIS (Netherlands)

    Yang, X.; Walboomers, X.F.; Bian, Z.; Jansen, J.A.; Fan, M.

    2011-01-01

    The following article from the Journal of Tissue Engineering and Regenerative Medicine, 'Effects of Pro-inflammatory Cytokines on Mineralization Potential of Rat Dental Pulp Stem Cells' by Yang X, Walboomers XF, Bian Z, Jansen JA, Fan M, published online on 11 July 2011 in Wiley Online Library

  6. Effects of Repeated Traumatic Brain Injuries in a Combat Setting

    Science.gov (United States)

    2011-12-01

    Metabolism, 30(2), 255-266. Cernak, I., Savic , J., Malicevic, Z., Zunic, G., Radosevic, P., Ivanovic, I., et al. (1996). Involvement of the central...Bian, X., & Savic , J. (2001). Ultrastructural and functional characteristics of blast injury-induced neurotrauma. The Journal of trauma, 50(4), 695-706

  7. Study of provenance properties on ancient celadon of different kilns with NAA

    International Nuclear Information System (INIS)

    Feng Songlin; Fan Dongyu; Feng Xiangqian; Xu Qing; Cheng Lin; Lei Yong; Shen Yueming; Zhang Wenjiang; Zhua Zhenxi

    2005-01-01

    Provenance characteristic is an important scientific parameter to identify ancient porcelain wares unearthed from sites and graves. The porcelain samples of Si-Long-Kou Yue kiln of Zhejiang Province, Hong-Zhou kiln of Jiangxi Province and Yao-Zhou kiln of Shanxi Province have been analyzed with neutron activation analysis (NAA). The experimental data were studied with statistic methods. The results show that the chemical compositions of porcelain body samples for three kilns were different. The difference was able to be identified. The body materials of both Si-Long-Kou Yue kiln and Hong-Zhou kiln of Jiangxi were similar. The samples of Yao-Zhou kiln in north of China existed obvious difference. (authors)

  8. Cone-beam computed tomography study of the root and canal morphology of mandibular permanent anterior teeth in a Chongqing population [Corrigendum

    Directory of Open Access Journals (Sweden)

    Yang ZY

    2016-03-01

    Full Text Available Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi ZhouDepartment of Preventive Dentistry, The College of Stomatology, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, People’s Republic of ChinaOn page 19, the author’s names were listed incorrectly as Yang Zhengyan, Lu Keke, Wang Fei, Li Yueheng, Zhou Zhi.The correct names are Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi Zhou.View the original paper here.

  9. Properties of Aerosols during a Dust Storm over the Beijing Area,

    Science.gov (United States)

    1983-12-12

    THE BEIJING AREA by Zhou Mingyu , Qu Shaohou, et al DTIC S ELECTE JAN 04 1984 N Lum E Approved for public release; distribution unlimited. 84 01 04 015...STORM OVER THE BEIJING AREA By: Zhou Mingyu , Qu Shaohou, et al. English~ pages: 22 Source: Huanjing Kexue Xuebao, Vol. 1, Nr. 3, September 1981, pp... Mingyu , Qu Shaohou, Song Ximing, Li Yuying, Yang Shaojin and Qian Qinfang Zhou, Qu, Song and Li of Institute of Atmospheric Physics, Chinese Academy

  10. Zhou Enlai and Chinese Grand Strategy

    National Research Council Canada - National Science Library

    Latham, Richard J

    1990-01-01

    ...." Contemporary Chinese writers actually write very little about modern Chinese strategy. When they do investigate the subject, they tend to begin with the late Qing dynasty and focus on events before 1949...

  11. Abstracts from the 15th International Myopia Conference

    Directory of Open Access Journals (Sweden)

    Alexandra Benavente-Perez

    2016-11-01

    rhesus monkeys Earl L Smith III, Baskar Arumugam, Li-Fang Hung, Lisa A. Ostrin, Klaus Trier, Monica Jong, Brien A. Holden O29 Application of SWATH™ based next generation proteomics (NGP in studying eye growth: opportunities and challenges Thomas Chuen Lam, Bing Zuo, Samantha Shan, Sally A. McFadden, Dennis Yan-yin Tse, Jingfang Bian, King-Kit Li, Quan Liu, Chi-ho To O30 How could emmetropization make use of longitudinal chromatic aberration? Timothy J. Gawne, John T. Siegwart Jr., Alexander H. Ward, Thomas T. Norton O31 Balance effect of dopamine D1 and D2 receptor subtype activation on refraction development Xiangtian Zhou O32 BMP gene expression changes in chick rpe in response to visual manipulations Yan Zhang, Yue Liu, Carol Ho, Eileen Phan, Abraham Hang, Emily Eng, Christine Wildsoet

  12. Wave Characteristics of Temperature Inversion Process of Nighttime Radiation,

    Science.gov (United States)

    1983-12-09

    CHARACTERISTICS OF TEMPERATURE INVERSION PROCESS OF NIGHTTIME RADIATION By: Zhou Mingyu and Zhang ¥i English pages: 8 Source: Kexue Tongbao, 1982, pp. 156...lJournal of Meteorology], 39 (1981), 1:70-81. 3. Drazin, P. G., J. Fluid. Mech., 4 (1958), 214-224. 4. Zhou Mingyu et al., QIXIANG XUEBAO, 38 (1980), 3: 250...258. 5. Emnanuel, C. B., B-L. Meteor., 5(1973), N(1/2)8 19-27. 6. Zhou Mingyu et al., J. Acoust. Soc., A. m., 68 (1980), 1: 303-308. 8 I iI

  13. Enhancement of Diosgenin Production in Plantlet and Cell Cultures ...

    African Journals Online (AJOL)

    Enhancement of Diosgenin Production in Plantlet and Cell Cultures of Dioscorea zingiberensis by Palmarumycin C13 from the Endophytic fungus, Berkleasmium sp. Dzf12. Y Mou, K Zhou, D Xu, R Yu, J Li, C Yin, L Zhou ...

  14. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 73; Issue 6. Magnons interaction of spinor Bose–Einstein condensates in an optical lattice. Yong-Qing Liu. Volume 73 Issue 6 ... Author Affiliations. Yong-Qing Liu1. Department of Physics and Electronics, XinZhou Teachers University, XinZhou, 034000, China ...

  15. RETRACTED: Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population.

    Science.gov (United States)

    Zhong, Weiqiang; Jiang, Zongpei; Zhou, Tian-Biao

    2015-12-01

    This article has been included in a multiple retraction: Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10

  16. RETRACTED: Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression.

    Science.gov (United States)

    Yang, Chun-Hua; Zhou, Tian-Biao

    2015-12-01

    This article has been included in a multiple retraction: Chun-Hua Yang and Tian-Biao Zhou Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression Journal of Renin-Angiotensin-Aldosterone System 1470320314568521, first published on February 3, 2015 doi: 10.1177/1470320314568521 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 Tian-Biao Zhou, Xue-Feng Guo, Zongpei

  17. RETRACTED: Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population.

    Science.gov (United States)

    Zhou, Tian-Biao; Guo, Xue-Feng; Jiang, Zongpei; Li, Hong-Yan

    2015-12-01

    The following article has been included in a multiple retraction: Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January

  18. Tanshinones as Effective Therapeutic Agents for Prostate Cancer

    Science.gov (United States)

    2011-06-01

    Y. Tian, T.-F. Chen, W. Ye, L. Li, F. Ni, J.-R. Zhou: Construction and screening of fractional library of Salvia Miltiorrhiza for the rapid...glutathione perturbation. Food Chem Toxicol 2008;46: 328–38. 19. Singh AV, Franke AA, Blackburn GL, Zhou JR. Soy phytochemicals prevent orthotopic growth and

  19. An analytical model and parametric study of electrical contact resistance in proton exchange membrane fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Zhiliang; Wang, Shuxin; Zhang, Lianhong [School of Mechanical Engineering, Tianjin University, Tianjin 300072 (China); Hu, S. Jack [Department of Mechanical Engineering, The University of Michigan, Ann Arbor, MI 48109-2125 (United States)

    2009-04-15

    This paper presents an analytical model of the electrical contact resistance between the carbon paper gas diffusion layers (GDLs) and the graphite bipolar plates (BPPs) in a proton exchange membrane (PEM) fuel cell. The model is developed based on the classical statistical contact theory for a PEM fuel cell, using the same probability distributions of the GDL structure and BPP surface profile as previously described in Wu et al. [Z. Wu, Y. Zhou, G. Lin, S. Wang, S.J. Hu, J. Power Sources 182 (2008) 265-269] and Zhou et al. [Y. Zhou, G. Lin, A.J. Shih, S.J. Hu, J. Power Sources 163 (2007) 777-783]. Results show that estimates of the contact resistance compare favorably with experimental data by Zhou et al. [Y. Zhou, G. Lin, A.J. Shih, S.J. Hu, J. Power Sources 163 (2007) 777-783]. Factors affecting the contact behavior are systematically studied using the analytical model, including the material properties of the two contact bodies and factors arising from the manufacturing processes. The transverse Young's modulus of chopped carbon fibers in the GDL and the surface profile of the BPP are found to be significant to the contact resistance. The factor study also sheds light on the manufacturing requirements of carbon fiber GDLs for a better contact performance in PEM fuel cells. (author)

  20. Effect of substitution of titanium by magnesium and niobium on ...

    Indian Academy of Sciences (India)

    Administrator

    Effect of substitution of titanium by magnesium and niobium on structure and piezoelectric properties in (Bi1/2. Na1/2. )TiO3 ceramics. ZHOU CHANG-RONG*, LIU XIN-YU, LI WEI-ZHOU. † and YUAN CHANG-LAI. Department of Information Material Science and Engineering, Guilin University of Electronic Technology,. Guilin ...

  1. Maillard reaction induces changes in saccharides and amino acids ...

    African Journals Online (AJOL)

    Fructose-lysine Model System and Pulsed Electric Field. Sterilization on Banana Juice Quality. Mod Food Sci Tec. 2015; 31: 220-226. 18. Deng Y. Comparison of Volatile Generation in. Serine/Threonine/Glutamine-Ribose/Glucose/Fructose. Model Systems. Food Industry 2010; (3): 58-61. 19. Zhou ZL, Xu ZQ, Zhou S, Wang ...

  2. Comparison differential transformation technique with Adomian decomposition method for linear and nonlinear initial value problems

    International Nuclear Information System (INIS)

    Abdel-Halim Hassan, I.H.

    2008-01-01

    In this paper, we will compare the differential transformation method DTM and Adomian decomposition method ADM to solve partial differential equations (PDEs). The definition and operations of differential transform method was introduced by Zhou [Zhou JK. Differential transformation and its application for electrical circuits. Wuuhahn, China: Huarjung University Press; 1986 [in Chinese

  3. Download this PDF file

    African Journals Online (AJOL)

    Dan Jiang 1*, Jian-Hong Zhou 2*, Jue Zhou 3 , Ying-Er Gu 2, Dong-Xia Yang 4, Qing .... Women were informed about the short- and long-term benefits of HRT. .... Current employment status .... randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong.

  4. Recent Research in Behind-Armor Blunt Trauma and Traumatic Brain Injury

    Science.gov (United States)

    2014-02-01

    Injury. Natl. Tech. Inf. Serv. 2006, ADA481896. 20. Cernak, I.; Wang, Z.; Jiang, J.; Bian, X.; Savic , J. Ultrastructural and Functional Characteristics...Malicevic, Z.; Savic J. Experimental Magnesium Depletion in Adult Rabbits Caused by Blast Overpressure. Magnes. Res. 1995, 8 (4), 249–259. 34. Cernak, I... Savic , J.; Malicevic, Z.; Zunic, G.; Radosevic, P.; Ivanovic, I.; Davidovic, L. Involvement of the Central Nervous System in the General Response

  5. Original Research Prevalence of antibody to hepatitis B core antigen ...

    African Journals Online (AJOL)

    There were 190 male (95%) and 10 female (5%) blood donors, with a mean age of 31.7 ± 7.9 years. ..... and 4.8% in Ecuador and Brazil among potential blood .... sciences. Nathadex 2003:115-129. 23. Liu Y, Li P, Li C, Zhou J, Wu C, Zhou YH.. Detection of hepatitis. B virus DNA among accepted blood donors in Nanjing, ...

  6. Bi Sparsity Pursuit: A Paradigm for Robust Subspace Recovery

    Science.gov (United States)

    2016-09-27

    Bian, Student Member, IEEE, and Hamid Krim, Fellow, IEEE Abstract The success of sparse models in computer vision and machine learning is due to the...16. SECURITY CLASSIFICATION OF: The success of sparse models in computer vision and machine learning is due to the fact that, high dimensional data...vision and machine learning is due to the fact that, high dimensional data is distributed in a union of low dimensional subspaces in many real-world

  7. Temperature hysteretic effect and its influence on colossal ...

    Indian Academy of Sciences (India)

    Financial support from IUC-DAEF, Mumbai, India is greatly appreciated. References. [1] G H Rao, J R Sun, J K Liang, W Y Zhou and X R Cheng, Appl. Phys. Lett. 69, 424 (1996). [2] J R Sun, G H Rao, J K Liang and W Y Zhou, Appl. Phys. Lett. 69, 3924 (1996). [3] J Baszynski, J Kovac, A Kowalczyk, J. Magn. Magn. Mater. 195 ...

  8. Archaeological Discoveries in the People’s Republic of China and Their Contribution to the Understanding of Chinese History

    Directory of Open Access Journals (Sweden)

    Xingcan Chen

    2009-11-01

    Full Text Available More than eight decades ago, the distinguished Chinese scholar Hu Shi (1891–1962 wrote an essay titled ‘My Views on Ancient History’, in which he said: My outlook regarding ancient history is, for the present, we should shorten the study of ancient history by two or three thousand years, and start our researches from the Book of Odes. When archaeology has become well developed, then we can slowly extend [our understanding of ancient history before the Eastern Zhou dynasty, using excavated historical evidence. Today, over eighty years later, Chinese history before the Eastern Zhou dynasty has been steadily reconstructed, step by step, from archaeological discoveries, without which, even the well-recognized deserved brilliance of ancient history, since the Eastern Zhou dynasty, would be dimmed.

  9. Zhou Enlai and the End of Unequal Treaties

    National Research Council Canada - National Science Library

    Kenny, Jr, James J

    1996-01-01

    China's rapprochement with the United States of America in 1971-72 represented one of the most dramatic realignments in world affairs since Hitler's invasion of the Soviet Union a generation earlier...

  10. ZHENG ZHOU: A Prospering City in Middle China

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ With a pleasant climate,Zhengzhou is welcoming all year round.The hottest month is July and the average temperature is about 27 C while the coldest month is January with an average temperature of -0.2 C.Autumn and spring ale the best and the peak tourist seasons.

  11. Věštění ve starověké Číně

    OpenAIRE

    Kubiš, Petr

    2011-01-01

    This thesis deals with divination in ancient China. The first part defines the theme and method, gives criticism of the primary source and presents a brief overview of the current state of research. The second part presents divination practices before the Eastern Zhou period. The third section provides a summary of divination practices in the Eastern Zhou period, categorizes the various oracles and provides related information. The fourth part introduces persons who performed divination pract...

  12. Scalable Inference of Discrete Data: User Behavior, Networks and Genetic Variation

    Science.gov (United States)

    2015-01-01

    and sparse observations. Closer to our model is the work of Titsias (2007), Zhou et al. (2012), and Broderick et al. (2013a). Titsias (2007) derives...truncated model (which also does not scale). Finally, Broderick et al. (2013a) give a more general class of hierarchical models than Zhou et al. (2012...but, again, only develop MCMC algorithms. Our model is simpler than and complements Broderick et al. (2013a)—Poisson factorization does not

  13. Introduction to Indian Ocean biogeochemical processes and ecological variability: Current understanding and emerging perspectives

    Digital Repository Service at National Institute of Oceanography (India)

    Wiggert, J.D.; Hood, R.R.; Naqvi, S.W.A.; Brink, K.H.; Smith, S.L.

    stream_size 35035 stream_content_type text/plain stream_name Geophys_Monogr_Ser_185_1.pdf.txt stream_source_info Geophys_Monogr_Ser_185_1.pdf.txt Content-Encoding UTF-8 Content-Type text/plain; charset=UTF-8 � Indian... inter- pretations of zooplankton observations obtained during the JGOFS cruises of the mid-�990s through the use of a food web synthesis that elucidates how mesozooplankton and mi- crozooplankton contribute to carbon flows within the Ara- bian Sea...

  14. Eyes Abroad

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    China International Fair for Investment & Trade helps push Chinese companies’ overseas ambitions A bustle of Chinese businesspeople roams the vast exhibition hall of the China International Fair for Investment & Trade(CIFIT) looking for opportunities to build cross-border scale. Among them is Zhou Meimei,Business Development Manager of the Shanghai Yiyang Electric Machinery Co. Ltd.,a manufacturer of mufflers and ventilation equipment. Although this was her first time attending the fair,Zhou did not go home empty-handed.

  15. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells

    Directory of Open Access Journals (Sweden)

    Yuan CX

    2015-03-01

    Full Text Available Chun-Xiu Yuan,1,2 Zhi-Wei Zhou,2,3 Yin-Xue Yang,4 Zhi-Xu He,3 Xueji Zhang,5 Dong Wang,6 Tianxing Yang,7 Si-Yuan Pan,8 Xiao-Wu Chen,9 Shu-Feng Zhou2 1Department of Oncology, General Hospital, Ningxia Medical University, Yinchuan, People’s Republic of China; 2Department of Pharmaceutical Science, College of Pharmacy, University of South Florida, Tampa, FL, USA; 3Guizhou Provincial Key Laboratory for Regenerative Medicine, Stem Cell and Tissue Engineering Research Center and Sino-US Joint Laboratory for Medical Sciences, Guiyang Medical University, Guiyang, 4Department of Colorectal Surgery, General Hospital, Ningxia Medical University, Yinchuan, 5Research Center for Bioengineering and Sensing Technology, University of Science and Technology Beijing, 6Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, People’s Republic of China; 7Department of Internal Medicine, University of Utah and Salt Lake Veterans Affairs Medical Center, Salt Lake City, UT, USA; 8Department of Pharmacology, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 9Department of General Surgery, The First People’s Hospital of Shunde, Southern Medical University, Shunde, People’s Republic of China Abstract: Gastric cancer is the second leading cause of cancer-related death worldwide, with a poor response to current chemotherapy. Danusertib is a pan-inhibitor of the Aurora kinases and a third-generation Bcr-Abl tyrosine kinase inhibitor with potent anticancer effects, but its antitumor effect and underlying mechanisms in the treatment of human gastric cancer are unknown. This study aimed to investigate the effects of danusertib on cell growth, apoptosis, autophagy, and epithelial to mesenchymal transition and the molecular mechanisms involved in human gastric cancer AGS and NCI-N78 cells. The results showed that danusertib had potent growth-inhibitory, apoptosis-inducing, and

  16. New interpretation of the dominant ore-controlling factor of the uranium ore field No. 322

    International Nuclear Information System (INIS)

    Liu Xiang; Yang Chongqiu

    1996-01-01

    The NE-trending fault structures in ore field NO. 322 are characterized by compress-shearing, left-Lateral left-slipping, having an obvious control over the Localisation of the ore field No. 322, and are the dominant ore-controlling factor of the ore field NO.322. Resulting from the sinistral displacement of the NE-trending fault, there is a pull-apart basin in the Feng Zhou area. The formation and evolution of the NE-trending fault zone and the Feng Zhou basin control the formation of uranium deposits of ore field No. 322

  17. New stable isotope records of sediment cores from the SE Arabian Sea - Inferences on the variations in monsoon regime during the late Quaternery

    Digital Repository Service at National Institute of Oceanography (India)

    Thamban, M.; Rao, V.P.

    , Vidyanagar 671 123, India We reconstruct here the changes in regional hydr o- graphy related to the fluctuations in Indian mo n soons du r ing the late Quaternary based on the stable isotope composition of the foraminifers and organic matter in three... value du r ing the early Holocene for the eastern Arabian Sea 21 . The SW monsoon intensity was very weak and the dry NE mo n soon was the dominant feature during the LGM in the Ar a bian Sea 3 . The cool winds of the north - easterly winter...

  18. Bacterioplankton abundance and production in Indian Ocean Regions

    Digital Repository Service at National Institute of Oceanography (India)

    Ramaiah, N.; Fernandes, V.; Rodrigues, V.V.; Paul, J.T.; Gauns, M.

    ) console. Although eu- photic depth varied widely in these locations, from as shallow as ~25 m in the bay to as deep as 150 m in the EIO, to be consistant with the JGOFS protocols followed widely, eight discrete depths (viz surface, 10, 20, 40, 60, 80... standing stocks calculated using 11 fg C per bacterial cell. Data from discrete sam- pling depths averaged from different stations in CAS, central Ara- bian Sea; EAS, eastern Arabian Sea; WB, western Bay of Bengal; CB, central Bay of Bengal; EIO...

  19. Reversible Redox-Induced Modulation of Sterics in an α-Diimine Ligand Coordinated to Gallium

    Energy Technology Data Exchange (ETDEWEB)

    Zarkesh, Ryan A. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Foster, Michael E. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Ichimura, Andrew S. [San Francisco State Univ., CA (United States); Anstey, Mitchell R. [Davidson College, Davidson, NC (United States)

    2017-07-01

    The ability to tune the steric envelope through redox events post-synthetically or in tandem with other chemical processes is a powerful tool that could assist in enabling new catalytic methodologies and understanding potential pitfalls in ligand design. The α-diimine ligand, dmp-BIAN, exhibits the peculiar and previously unreported feature of varying steric profiles depending on oxidation state when paired with a main group element. A study of the factors that give rise to this behaviour as well as its impact on the incorporation of other ligands is performed.

  20. Data-Model Assimilation at the FACE and AmeriFlux Sites Toward Predictive Understanding of Carbon Sequestration at Ecosystem and Regional Scales

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Yiqi [Univ. of Oklahoma, Norman, OK (United States)

    2013-01-09

    The project was conducted during the period from 9/1/2007 to 8/31/2011 with three major tasks: (1) development of data assimilation (DA) techniques for terrestrial carbon research; (2) applications of DA techniques to analysis of carbon cycle at Duke and other FACE sites; and (3) inverse analysis at AmeriFlux sites. During this period, we have developed a variety of techniques, including (1) ensemble Kalman filter to estimate model parameters or state variables (Gao et al. 2011), (2) Conditional inversion to estimate parameters of a carbon cycle model (Wu et al. 2009), and (3) various methods to quantify uncertainty of estimated parameters and predicted C sinks (e.g., Weng et al. 2011), and (4) information theory to evaluate information content of different model structures and data sets (Weng and Luo 2011). We applied the DA techniques to and did modeling at the Duke FACE and other global change experimental sites. We addressed the following issues: (1) interactive effects of CO2, warming and precipitation on ecosystem processes (e.g., Luo et al. 2008, Weng and Luo 2008, Zhou et al. 2008), (2) effects of warming on estimated parameters related to photosynthesis and residence times (Zhou et al. 2010); and (3) uncertainty in estimated parameters and predicted C sequestration (Gao et al. 2011, Weng and Luo 2011). In addition, we have done data assimilation to estimate carbon residence and carbon sequestration in US continent (Zhou and Luo 2008) and temperature sensitivity at the global scale (Zhou et al. 2009).

  1. Accelerator mass spectrometry and its applications in environmental science

    International Nuclear Information System (INIS)

    Liu Kexin; Li Kun; Ma Hongji; Guo Zhiyu

    2001-01-01

    Some important work worldwide in environmental science, like urban air pollution, discharges of radioactive wastes from nuclear plants, and global climate change were introduced. Based on the improvements of facility and studies on 14 C dating method, a precision better than 0.5% has been reached for the PKUAMS. A large number of samples have been measured for the Xia-Shang-Zhou Chronology project. 14 C data of PKUAMS have made important contributions to creation of more reliable chronological table of Xia, Shang and Zhou dynasties. The improvements of PKUAMS are of benefit to the applications in environmental science in the future

  2. モンゴル時代の「道仏論争」の実像:クビライの中国支配への道

    OpenAIRE

    中村淳

    1994-01-01

    The disputes between one sect of Taoism Quan-zhen-jiao (全真教) and the Zen sect (禅宗) of Buddhism arose three times in the reign of the Emperor Möngke. According to the Zhi-yuan-bian-wei-lu (至元辯偽録) compiled by a Buddhist monk which have been regarded as the only relevant literature, it is reported that these disputes ended in a victory for Buddhism. As the result of examining relevant parts of a report of mission composed by William of Rubruck and a Tibetan chronicle Hu-lan-deb-ther, we have fou...

  3. Study of provenance properties on ancient porcelain of Yue Kiln at Si-long-kou with NAA

    International Nuclear Information System (INIS)

    Feng Songlin; Fan Dongyu; Feng Xiangqian; Cheng Lin; Lei Yong; Xu Qing; Quan Huishan; Shen Yueming; Zhou Zhexi; Zhang Wenjiang

    2005-01-01

    Chinese ancient porcelain history has lasted about three thousands years from Shang Dynasty (1100∼1600 BC). A large amount of ancient porcelain sherds with accuracy provenance and ages were excavated from a lot of kiln sites in China. Archaeologists and ceramic experts have recognized and researched it with excavated stratum, utensil shape, body quality, glaze color and painting pattern. However, the appearance characteristic of some ancient porcelain manufactured in different kilns is similar. Therefore, it is still difficult to identify the provenance and ages of the samples excavated from some sites using traditional methods. Up, to now, many problems of Chinese ancient porcelain are confused for archaeologist and collecting experts. The elemental composition of ancient porcelain shows certain information of provenance and age. Especially, the sorts and contents of the elements in porcelain didn't change, so it is very useful to determine the provenance of ancient porcelain with elemental composition characteristics. Provenance characteristic is the important scientific information to identify ancient porcelain wares excavated from sites and graves. The porcelain samples of Si-Long-Kou Yue kiln in Zhejiang Province of china have been analyzed with NAA in this paper. The provenance characteristic was compared with it of Hong-Zhou kiln of Jiang-Xi Province and Yao-Zhou kiln of Shan-Xi Province. The experimental data were studied with statistic methods. The results show that the chemical compositions of porcelain body samples for three kilns were different. The difference was been able identified. The porcelain body materials of both Si-Long-Kou Yue kiln and Hong-Zhou kiln of Jiang-Xi were similar. The samples of Yao-Zhou kiln in north of China existed obvious difference.

  4. On an inequality of Sagher and Zhou concerning Stein's lemma

    Czech Academy of Sciences Publication Activity Database

    Announi, M.; Grafakos, L.; Honzík, Petr

    2009-01-01

    Roč. 60, č. 3 (2009), s. 297-306 ISSN 0010-0757 Institutional research plan: CEZ:AV0Z10190503 Keywords : lacunary series * sequences * Rademacher functions Subject RIV: BA - General Mathematics Impact factor: 0.389, year: 2009

  5. Precision comparison of the erosion rates derived from 137Cs measurements models with predictions based on empirical relationship

    International Nuclear Information System (INIS)

    Yang Mingyi; Liu Puling; Li Liqing

    2004-01-01

    The soil samples were collected in 6 cultivated runoff plots with grid sampling method, and the soil erosion rates derived from 137 Cs measurements were calculated. The models precision of Zhang Xinbao, Zhou Weizhi, Yang Hao and Walling were compared with predictions based on empirical relationship, data showed that the precision of 4 models is high within 50m slope length except for the slope with low slope angle and short length. Relatively, the precision of Walling's model is better than that of Zhang Xinbao, Zhou Weizhi and Yang Hao. In addition, the relationship between parameter Γ in Walling's improved model and slope angle was analyzed, the ralation is: Y=0.0109 X 1.0072 . (authors)

  6. An improved model for predicting electrical contact resistance between bipolar plate and gas diffusion layer in proton exchange membrane fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Zhiliang; Wang, Shuxin [School of Mechanical Engineering, Tianjin University, Tianjin 300072 (China); Zhou, Yuanyuan; Lin, Guosong; Hu, S. Jack [Department of Mechanical Engineering, The University of Michigan, Ann Arbor, MI 48109-2125 (United States)

    2008-07-15

    Electrical contact resistance between bipolar plates (BPPs) and gas diffusion layers (GDLs) in PEM fuel cells has attracted much attention since it is one significant part of the total contact resistance which plays an important role in fuel cell performance. This paper extends a previous model by Zhou et al. [Y. Zhou, G. Lin, A.J. Shih, S.J. Hu, J. Power Sources 163 (2007) 777-783] on the prediction of electrical contact resistance within PEM fuel cells. The original microscale numerical model was based on the Hertz solution for individual elastic contacts, assuming that contact bodies, GDL carbon fibers and BPP asperities are isotropic elastic half-spaces. The new model features a more practical contact by taking into account the bending behavior of carbon fibers as well as their anisotropic properties. The microscale single contact process is solved numerically using the finite element method (FEM). The relationship between the contact pressure and the electrical resistance at the GDL/BPP interface is derived by multiple regression models. Comparisons of the original model by Zhou et al. and the new model with experimental data show that the original model slightly overestimates the electrical contact resistance, whereas a better agreement with experimental data is observed using the new model. (author)

  7. Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis

    Directory of Open Access Journals (Sweden)

    Zhou X

    2018-05-01

    Full Text Available Xian-guo Zhou,1,2,* Xiao-liang Huang,1,2,* Si-yuan Liang,1–3 Shao-mei Tang,1,2 Si-kao Wu,1,2 Tong-tong Huang,1,2 Zeng-nan Mo,1,2,4 Qiu-yan Wang1,2,5 1Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 2Guangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 3Department of Colorectal Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 4Department of Urology and Nephrology, The First Affiliated Hospital of Guangxi, Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 5Guangxi Colleges and Universities Key Laboratory of Biological Molecular Medicine Research, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China *These authors contributed equally to this work Introduction: Colorectal cancer (CRC is the fourth most common cause of cancer-related mortality worldwide. The tumor, node, metastasis (TNM stage remains the standard for CRC prognostication. Identification of meaningful microRNA (miRNA and gene modules or representative biomarkers related to the pathological stage of colon cancer helps to predict prognosis and reveal the mechanisms behind cancer progression.Materials and methods: We applied a systems biology approach by combining differential expression analysis and weighted gene co-expression network analysis (WGCNA to detect the pathological stage-related miRNA and gene modules and construct a miRNA–gene network. The Cancer Genome Atlas (TCGA colon adenocarcinoma (CAC RNA-sequencing data and miRNA-sequencing data were subjected to WGCNA analysis, and the GSE29623, GSE35602 and GSE39396 were utilized to validate and

  8. Effects of combined dietary supplementation with fenofibrate and Schisandrae Fructus pulp on lipid and glucose levels and liver function in normal and hypercholesterolemic mice

    Directory of Open Access Journals (Sweden)

    Zhu PL

    2015-02-01

    Full Text Available Pei-Li Zhu,1 Si-Yuan Pan,1 Shu-Feng Zhou,2 Yi Zhang,1 Xiao-Yan Wang,1 Nan Sun,1 Zhu-Sheng Chu,1 Zhi-Ling Yu,3 Kam-Ming Ko41Department of Pharmacology, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA; 3School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, People’s Republic of China; 4Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, People’s Republic of ChinaBackground: Currently, combined therapy using herbs and synthetic drugs has become a feasible therapeutic intervention against some diseases. The purpose of this study was to assess the effects of supplementation with fenofibrate (FF, a chemical drug used for the treatment of hyperlipidemia, and the aqueous extract of Schisandrae Fructus (SF, a Chinese herb pulp (AqSF-P or an SF-related synthetic analog, bicyclol (BY, on serum/hepatic lipid levels and liver status in normal and hypercholesterolemic (HCL mice.Methods: Male mice obtained from the Institute of Cancer Research (ICR were fed on a normal diet (ND or high cholesterol/bile salt (0.5%/0.15%, w/w diet (HCBD containing FF (0.03% or 0.1%, w/w with or without AqSF-P (0.3%-9.0%, based on crude herbal material, w/w or BY (0.025%, w/w for 10 days. Then serum lipid levels and alanine aminotransferase (ALT activity, as well as hepatic triglyceride (TG, total cholesterol (TC, and glucose levels, were measured.Results: Oral supplementation with FF significantly reduced serum and hepatic TG, TC, and hepatic glucose levels (approximately 79% in mice fed with ND or HCBD. FF supplementation combined with AqSF-P or BY increased FF-induced reduction in hepatic TC and TG contents in ND-fed mice (up to 67% and in HCBD-fed mice (up to 54%, when compared with FF supplementation alone. Hepatic glucose-lowering effect of FF was

  9. Disease: H01679 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available r resection, percutaneous approach, endoscopic approach and laser lithotripsy. Li...hang M, Xie HY, Zhou L, Zheng SS ... TITLE ... Management hepatolithiasis with operative choledochoscopic FREDDY laser

  10. Model-checking dense-time Duration Calculus

    DEFF Research Database (Denmark)

    Fränzle, Martin

    2004-01-01

    Since the seminal work of Zhou Chaochen, M. R. Hansen, and P. Sestoft on decidability of dense-time Duration Calculus [Zhou, Hansen, Sestoft, 1993] it is well-known that decidable fragments of Duration Calculus can only be obtained through withdrawal of much of the interesting vocabulary...... of this logic. While this was formerly taken as an indication that key-press verification of implementations with respect to elaborate Duration Calculus specifications were also impossible, we show that the model property is well decidable for realistic designs which feature natural constraints...... suitably sparser model classes we obtain model-checking procedures for rich subsets of Duration Calculus. Together with undecidability results also obtained, this sheds light upon the exact borderline between decidability and undecidability of Duration Calculi and related logics....

  11. Rapid and non-destructive discrimination of tea varieties by near ...

    African Journals Online (AJOL)

    Rapid and non-destructive discrimination of tea varieties by near infrared diffuse reflection spectroscopy coupled with classification and regression trees. SM Tan, RM Luo, YP Zhou, H Gong, Z Tan ...

  12. Microarray analysis of genes affected by salt stress in tomato | Zhou ...

    African Journals Online (AJOL)

    This study has provided a set of candidate genes, especially those in the regulatory machinery that can be further investigated to define salt stress in tomato and other plant species. Keywords: Antioxidants, cellular metabolism, cell wall, chaperonine, ethylene, protein kinase, tomato, transcription regulator, translation ...

  13. Improving research capacity on information society issues | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-21

    Apr 21, 2016 ... Baohua Zhou is now an associate professor at Fudan University. ... How can we improve women's livelihoods, enabling them to pursue better paid and ... students, researchers, and faculty to Canadian educational institutions,.

  14. Electrical and microstructural properties of CaTiO3-doped K1/2Na1 ...

    Indian Academy of Sciences (India)

    health and environment. Therefore, in ... (Sawada et al 2003), bismuth sodium titanate (Zhou and Xin. 2007 ... these KNN systems possess low-temperature stability for. PPT near to ... CTO phase was not observed; probably due to problems to.

  15. Influence of free water content on the compressive mechanical ...

    Indian Academy of Sciences (India)

    tars with different water content, the upward section of the stress–strain curve ..... Recent work by Zhou & Hao (2008) also provide computational confirmation ... these volume change may be closely related to micro-capillarity action in the ...

  16. Molecular cloning, polymorphisms, and expression analysis of the RERG gene in indigenous Chinese goats.

    Science.gov (United States)

    Sui, M X; Wang, H H; Wang, Z W

    2015-11-24

    The current study aimed to investigate the coding sequence, polymorphisms, and expression of the RERG gene in indigenous Chinese goats. cDNA of RERG, obtained through reverse transcription PCR was analyzed using bioinformatic techniques. Polymorphisms in the exon regions of the RERG gene were identified and their associations with growth traits in three varieties of indigenous Chinese goats were investigated. Expression of the RERG gene in three goat breeds of the same age was detected using real-time quantitative PCR. The results revealed that the cDNA of RERG, which contained a complete open reading frame of 20-620 bp, was 629 bp in length. The associated accession numbers in GenBank are JN672576, JQ917222, and JN580309 for the QianBei Ma goat, the GuiZhou white goat, and the GuiZhou black goat, respectively. Four consistent SNP sites were found in the exon regions of the RERG gene for the three goat breeds. mRNA expression of the RERG gene differed between different tissues in adult goats of same age. The highest expression was observed in lung and spleen tissues, while the lowest expression was recorded in thymus gland tissue. In addition, the expression of the RERG gene in the muscle of Guizhou white goat, GuiZhou black goat, and QianBei Ma goat decreased sequentially. Our results lay the foundations for further investigation into the role of the RERG gene in goat growth traits.

  17. Tissue-specific alternative splicing and expression of ATP1B2 gene

    African Journals Online (AJOL)

    user6

    2012-05-15

    May 15, 2012 ... retention; these isoforms were found in liver, kidney, muscle and breast tissues. ... lower levels than the complete ATP1B2 gene transcript in all the ... temperature. ... growth, differentiation, and disease (Zhou et al., 2002;.

  18. Molecular cloning and expression profiling of a chalcone synthase ...

    Indian Academy of Sciences (India)

    health-protecting components in the human diet (Sugihara et al. 1999; Dugas et al. ... increasing health problems in many parts of the world, ways to commercially produce ...... Fudan University, Doctor dissertation. Lu X., Zhou W. and Gao F.

  19. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. AI-PING ZHOU1 XIAO-QING LI2. School of Physics and Optoelectronic Engineering, Shandong University of Technology, Zibo, Shandong, People's Republic of China; Department of Physics, Nanjing Normal University, Nanjing, People's Republic of China ...

  20. Investigation of Solid Dispersion of Atorvastatin Calcium in ...

    African Journals Online (AJOL)

    ATC), a poorly ... characteristics of the formulations were determined in vitro, while the ... drying [9] and supercritical fluid precipitation [10]. ... calibrate for the temperature scale and energy. ..... Yang W, Tam J, Miller DA, Zhou J, McConville JT,.

  1. schoolchildren in Kinondoni and Temeke Districts, Tanzania

    African Journals Online (AJOL)

    User

    Ethical clearance was obtained from the Research and Publication Committee of the Muhimbili .... not conform to the findings by Zhou et al. (2016) ... end (e.g. non response) and as information bias or misclassification related to the information.

  2. Simulation of adiabatic thermal beams in a periodic solenoidal magnetic focusing field

    Directory of Open Access Journals (Sweden)

    T. J. Barton

    2012-12-01

    Full Text Available Self-consistent particle-in-cell simulations are performed to verify earlier theoretical predictions of adiabatic thermal beams in a periodic solenoidal magnetic focusing field [K. R. Samokhvalova, J. Zhou, and C. Chen, Phys. Plasmas 14, 103102 (2007PHPAEN1070-664X10.1063/1.2779281; J. Zhou, K. R. Samokhvalova, and C. Chen, Phys. Plasmas 15, 023102 (2008PHPAEN1070-664X10.1063/1.2837891]. In particular, results are obtained for adiabatic thermal beams that do not rotate in the Larmor frame. For such beams, the theoretical predictions of the rms beam envelope, the conservations of the rms thermal emittances, the adiabatic equation of state, and the Debye length are verified in the simulations. Furthermore, the adiabatic thermal beam is found be stable in the parameter regime where the simulations are performed.

  3. Improvement of One Quantum Encryption Scheme

    Science.gov (United States)

    Cao, Zhengjun; Liu, Lihua

    2012-01-01

    Zhou et al. proposed a quantum encryption scheme based on quantum computation in 2006 [N. Zhou et al., Physica A362 (2006) 305]. Each qubit of the ciphertext is constrained to two pairs of conjugate states. So, its implementation is feasible with the existing technology. But it is inefficient since it entails six key bits to encrypt one message bit, and the resulting ciphertext for one message bit consists of three qubits. In addition, its security cannot be directly reduced to the well-known BB84 protocol. In this paper, we improve it using the technique developed in BB84 protocol. The new scheme entails only two key bits to encrypt one message bit. The resulting ciphertext is just composed of two qubits. It saves about a half cost without the loss of security. Moreover, the new scheme is probabilistic instead of deterministic.

  4. Studies on mineral nutrition and safety of wild rice (Oryza L.).

    Science.gov (United States)

    Jiang, Shuli; Shi, Chunhai; Wu, Jianguo

    2009-01-01

    Mineral element contents of five wild rice were analyzed, including mineral nutrient elements such as phosphorus (P), potassium (K), calcium (Ca), sodium (Na), magnesium (Mg), iron (Fe), zinc (Zn), copper (Cu), manganese (Mn) and selenium (Se), and the potential toxic elements arsenic (As), mercury (Hg), lead (Pb) and cadmium (Cd). The results showed that the contents of K, Mg, Fe, Zn, Cu, Mn and Se in five wild rice materials were much higher than the cultivate variety Zhou 903 in both brown and milled rice. Wild rice also had lower potential toxic element contents of Hg, Pb and Cd compared with Zhou 903 in brown rice and milled rice, respectively. Among five wild rice samples, WR-3 from Uganda had the highest level of P, K, Ca, Na, Mg, Fe, Zn, Mn and Se, and the lowest contents of Hg, Pb and Cd.

  5. Sintering, camber development of layer composites and a new ...

    Indian Academy of Sciences (India)

    a significant benefit to develop LTCC ZnTiO3-based cera- mics (Liu et al 2007; Zhou ... zero-shrinkage-difference (ZSD) technology combined with controlling cooling stage ... composition and to control their radial shrinkage (Green et al 2008).

  6. Küpsemas on uus kunstiskandaal : vene kuraator Joseph Backstein on kuulsustest kokku pannud omaette biennaali / Ants Juske

    Index Scriptorium Estoniae

    Juske, Ants, 1956-2016

    1998-01-01

    Tallinnas Eesti Kunstimuuseumis avati külalisnäitus 'Medialisatsioon', kus on eksponeeritud Oleg Kuliku, Moskva rühmituse AES, Andres Serrano New Yorgist, Zhou Tiehai Shanghaist jt., kokku üle 20 kunstniku meedialooming. Ando Keskküla kommentaar

  7. Characterization of microbial degradation of oxytetracycline in river ...

    African Journals Online (AJOL)

    DZOMBA

    2015-01-07

    Jan 7, 2015 ... Effectiveness of UV, ozone and other advanced oxidation techniques to .... stored in a fridge until HPLC-UV analysis (Zhou et al., 2011). Sediment .... a source of carbon by releasing enzymes into the solution. (Migliore et al.

  8. Reference: SITE3SORPS1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available SITE3SORPS1 Villain P, Clabault G, Mache R, Zhou DX S1F binding site is related to ...but different from the light-responsive GT-1 binding site and differentially represses the spinach rps1 prom

  9. Reference: 438 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ity and drought tolerance in Arabidopsis thaliana. 18 6902-12 16943431 2006 Sep Molecular and cellular bio...logy Chen Zhizhong|Gong Zhizhong|Hong Xuhui|Jablonowski Daniel|Ren Xiaozhi|Schaffrath Raffael|Zhang Hairong|Zhou Xiaofeng|Zhu Jian-Kang

  10. African Journal of Biotechnology - Vol 10, No 37 (2011)

    African Journals Online (AJOL)

    7130 ... G Lu, Y Shen, W Qian, L Shen, Q Qiao, M Li, Z Wang, 7136-7142 ... LN Zhen, K Wang, YJ Zhang, H Zhou, 7161-7165 ... Effect of cadmium hyperaccumulation on antioxidative defense and proline accumulation of Solanum nigrumL.

  11. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 130; Issue 2. Polynuclear and one-dimensional cyanide-bridged heterobimetallic complexes: synthesis, crystal structures and magnetic properties. JINGWEN SHI WENLONG LAN YIN ZHOU CHONGCHONG XUE QINGYUN LIU DAOPENG ZHANG. Volume 130 Issue ...

  12. Species delimitation and interspecific relationships of the genus Orychophragmus (Brassicaceae inferred from whole chloroplast genomes

    Directory of Open Access Journals (Sweden)

    Huan Hu

    2016-12-01

    Full Text Available IntroductionIt is rather difficult to delimit recently diverged species and construct their interspecific relationships because of insufficient informative variations of sampled DNA fragments (Schluter, 2000; Arnold, 2006. The genome-scale sequence variations were found to increase the phylogenetic resolutions of both high- and low-taxonomic groups (e.g., Yoder et al., 2013; Lamichhaney et al., 2015. It is still expensive to collect nuclear genome variations between species for most none-model genera without the reference genome. However, chloroplast genomes (plastome are relatively easy to be assembled to examine interspecific relationships for phylogenetic analyses, especially in addressing unresolved relationship at low taxonomic levels (Wu et al., 2010; Nock et al., 2011; Yang et al., 2013; Huang et al., 2014; Carbonell-Caballero et al., 2015. Plastomes are haploid with maternal inheritance in most angiosperms (Corriveau and Coleman, 1988; Zhang and Liu, 2003; Hagemann, 2004 and are highly conservative in gene order and genome structure with rare recombinations (Jansen et al., 2007; Moore et al., 2010. In this study, we aimed to examine species delimitation and interspecific relationships in Orychophragmus through assembling chloroplast genomes of multiple individuals of tentatively delimited species (Hu et al., 2015a. Orychophragmus is a small genus in the mustard family (Brassicaceae, Cruciferae distributed in northern, central, and southeastern China (Zhou et al., 2001. Its plants have been widely cultivated as ornamentals, vegetables, or source of seed oil (Sun et al., 2011. Despite controversial species delimitations in the genus (Zhou et al., 1987; Tan et al., 1998; Wu and Zhao, 2003; Al-Shehbaz and Yang, 2000; Zhou et al., 2001; Sun et al., 2012, our recent study based on nuclear (nr ITS sequence variations suggested the recognition of seven species (Hu et al., 2015a. Orychophragmus is sister to Sinalliaria, which is a genus endemic

  13. High-temperature thermoelectric properties of AgxYyCa2⋅ 8Co4O9 ...

    Indian Academy of Sciences (India)

    temperature thermoelectric properties of AgYCa2.8Co4O9 + ceramics. Youjin Zheng Hui Zhou Tengzhou Ma Guihong Zuo Hongtao Li Taichao Su Chunlei Wu Hailiang Huang Dan Wang Longcheng Yin. Volume 37 Issue 5 August 2014 pp 963- ...

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. YIN ZHOU. Articles written in Journal of Chemical Sciences. Volume 130 Issue 2 February 2018 pp 19. Polynuclear and one-dimensional cyanide-bridged heterobimetallic complexes: synthesis, crystal structures and magnetic properties · JINGWEN SHI WENLONG LAN YIN ...

  15. Lanthanide metal-organic frameworks

    International Nuclear Information System (INIS)

    Cheng, Peng

    2015-01-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  16. Lanthanide metal-organic frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Peng (ed.) [Nankai Univ., Tianjin (China). Dept. of Chemistry

    2015-03-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  17. Membrane Reflector Vertical Cavity Lasers at Near- and Midwave-Infrared

    Science.gov (United States)

    2014-05-30

    independent broadband reflectors based on cross-stacked gratings, Optics Express, (04 2011): 9050. doi: 10.1364/OE.19.009050 Tapas Kumar Saha, Mingyu Lu... Mingyu Lu, Huiqing Zhai, Deyin Zhao, Weidong Zhou. Design of a compact grating coupler with controllable linewidths via transverse resonance and

  18. The Optimal Portfolio Selection Model under g-Expectation

    Directory of Open Access Journals (Sweden)

    Li Li

    2014-01-01

    complicated and sophisticated, the optimal solution turns out to be surprisingly simple, the payoff of a portfolio of two binary claims. Also I give the economic meaning of my model and the comparison with that one in the work of Jin and Zhou, 2008.

  19. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yu-Song Guo Zhong-Duo Wang Cheng-Zhong Yan Yu-Lan Zhang Jin-Nan Zheng Yuan-Min Xu Tao Du Chu-Wu Liu · More Details Fulltext PDF ... Aifu Yang Dapeng Sun Shikai Liu Ying Dong Zhong Chen Zunchun Zhou · More Details Fulltext ...

  20. 75 FR 81565 - Initiation of Antidumping and Countervailing Duty Administrative Reviews and Request for...

    Science.gov (United States)

    2010-12-28

    ... Jiangsu Inter-China Group Corporation (previously operated as Zhenjiang Inter-China Import & Export Co...., Ltd aka Wanli Tools Group Zhenjiang Inter-China Import & Export Co., Ltd.. THE PEOPLE'S REPUBLIC OF...., Ltd Xinjiang Top Agricultural Products Co., Ltd..... XuZhou Simple Garlic Industry Co., Ltd Yantai...

  1. Synthesis of γ-Al2O3 nanowires through a boehmite precursor route

    Indian Academy of Sciences (India)

    has applications in absorbent, catalyst carrier and reinforce- ment of ceramic .... nia into the transparent solution, Al(OH)3 with colloidal form generates .... 99 1823. Zhou J, Deng S Z, Chen J, She J C and Xu N S 2002 Chem. Phys. Lett. 365 505.

  2. Browse Title Index

    African Journals Online (AJOL)

    Items 401 - 450 of 1178 ... Y-X Zhou, J Chen, J-P Li, Y-L Wang, X-D Jin ... Vol 4, No 3 (2007), Comparative Chemical And Analgesic Properties Of Essential Oils ... Pilar Carranza-Rosales, Omar Heredia-Rodríguez, Gerardo Lozano-Garza, Angel ...

  3. Cofactor interactions in the activation of tissue non-specific alkaline ...

    African Journals Online (AJOL)

    JTEkanem

    stabilization of protein structure and regulation of enzymatic ... structure of ALP at low and high concentrations respectively4,5. ..... Zhang, Y.X., Zhu, Y., Xi, H.W., Liu, Y.L. and Zhou, H.M. ... Garen, A. and Levinthal, C. (1960) A fine structure ...

  4. Synthesis of substituted guanidines using Zn–Al hydrotalcite catalyst

    Indian Academy of Sciences (India)

    Zn–Al HT was prepared by co-precipitation method and charac- terized by ... tion of highly functionalized guanidines.4 Linton et al. explained a ..... Pi C, Zhu Z, Weng L, Chen Z and Zhou X 2007 Chem. Commun. ... J P 2000 J. Mater. Chem.

  5. ONLINE RESOURCES Development and characterization of 37 ...

    Indian Academy of Sciences (India)

    Navya

    2016-12-23

    Dec 23, 2016 ... loci of Megalobrama hoffmanni by next-generation sequencing technology and ... The minimum motif repeat was defined as 5 for hexanucleotides, 10 for ..... Tan X. C., Li X. H., Lin J. Z., Zhou D. H., Gao X. and Li J.M. 2009.

  6. Li et al., Afr J Tradit Complement Altern Med., (2017) 14 (1): 62-72 ...

    African Journals Online (AJOL)

    The aim of the study was to develop a more efficient drug which could not .... The test was carried out using the described technique previously (Zhou et al., 2008). ..... in part by stem cells (Ito et al., 2005, Levy et al., 2005), while hair follicles are ...

  7. On the contributions of photorespiration and compartmentation to the contrasting intramolecular 2H profiles of C3 and C4 plant sugars

    Science.gov (United States)

    Youping Zhou; Benli Zhang; Hilary Stuart-Williams; Kliti Grice; Charles H. Hocart; Arthur Gessler; Zachary E. Kayler; Graham D. Farquhar

    2018-01-01

    Compartmentation of C4 photosynthetic biochemistry into bundle sheath (BS) and mesophyll (M) cells, and photorespiration in C3 plants is predicted to have hydrogen isotopic consequences for metabolites at both molecular and site-specific levels. Molecular-level evidence was recently reported (Zhou et al., 2016), but...

  8. Notes on Cordulegaster Leach, and Neallogaster Cowley, from China, and the identity of Anotogaster annandalei Fraser (Insecta: Odonata: Anisoptera: Cordulegastridae)

    NARCIS (Netherlands)

    Pelt, van G.J.

    1996-01-01

    A translation of the Chinese description of a female of Neallogaster annandalei (Fraser, 1923), by Zhou (1988) is given and compared with the original description of Anotogaster annandalei. It is concluded that this species should be included in the genus Cordulegaster. A translation of the original

  9. Novel D–π–A dye sensitizers of polymeric metal complexes with ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 38; Issue 2. Novel D––A dye sensitizers of polymeric metal complexes with triphenylamine derivatives as donor for dye-sensitized solar cells: synthesis, characterization and application. Guipeng Tang Jun Zhou Wei Zhang Jiaomei Hu Dahai Peng Qiufang Xie ...

  10. Human communication of emotion via sweat : How specific is it? (abstract)

    NARCIS (Netherlands)

    Smeets, M.A.M.; Toet, A.; Duinkerken, R.; Groot, J. de; Kaldewaij, A.; Hout, M.A. van den; et al

    2011-01-01

    Females evaluate ambiguous facial expression – morphed between happy and fearful – faces as more fearful when exposed to fear sweat as compared to control odor (Zhou & Chen, 2009). We investigated the specificity of this effect, i.e. whether processing of fearful faces is affected specifically by

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Guanshui Chen Daren Pan1 Yifei Zhou Sheng Lin2 Xiangde Ke. College of Life Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, the People's Republic of China; College of Crop Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, the People's Republic ...

  12. Genetics Home Reference: congenital central hypoventilation syndrome

    Science.gov (United States)

    ... Kravis EM, Zhou L, Rand CM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B mutations and phenotype. Am J Respir Crit ... BA, Leurgans SE, Berry-Kravis EM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B genotype determines risk for sudden death. Pediatr ...

  13. Cardioprotective effect of Shenxiong glucose injection on acute ...

    African Journals Online (AJOL)

    Yu JH, Wang LY, Akinyi M, Li YH, Duan ZZ, Zhu Y, Fan. GW. Danshensu protects ... Yin Y, Guan Y, Duan JL, Wei G, Zhu YR, Quan W, Guo. C, Zhou D, Wang YH, ... HM, Han J, Kang D. Lamotrigine increases intracellular. Ca(2+) levels and ...

  14. Single-photon switch: Controllable scattering of photons inside a one-dimensional resonator waveguide

    Science.gov (United States)

    Zhou, L.; Gong, Z. R.; Liu, Y. X.; Sun, C. P.; Nori, F.

    2010-03-01

    We analyze the coherent transport of a single photon, which propagates in a one-dimensional coupled-resonator waveguide and is scattered by a controllable two-level system located inside one of the resonators of this waveguide. Our approach, which uses discrete coordinates, unifies low and high energy effective theories for single-photon scattering. We show that the controllable two-level system can behave as a quantum switch for the coherent transport of a single photon. This study may inspire new electro-optical single-photon quantum devices. We also suggest an experimental setup based on superconducting transmission line resonators and qubits. References: L. Zhou, Z.R. Gong, Y.X. Liu, C.P. Sun, F. Nori, Controllable scattering of photons inside a one-dimensional resonator waveguide, Phys. Rev. Lett. 101, 100501 (2008). L. Zhou, H. Dong, Y.X. Liu, C.P. Sun, F. Nori, Quantum super-cavity with atomic mirrors, Phys. Rev. A 78, 063827 (2008).

  15. Evaluation of Permanent Deformation of Unmodified and Rubber-Reinforced SMA Asphalt Mixtures Using Dynamic Creep Test

    Directory of Open Access Journals (Sweden)

    Herda Yati Katman

    2015-01-01

    Full Text Available This paper presents the evaluation of permanent deformation of rubber-reinforced SMA asphalt mixtures by using dynamic creep test. The effect of trans-polyoctenamer as a cross-linking agent in permanent deformation of rubberized mixtures was also evaluated. Dynamic creep test was conducted at different stress levels (200 kPa, 400 kPa and temperatures (40°C, 50°C. Permanent deformation parameters such as dynamic creep curve, ultimate strain, and creep strain slope (CSS were used to analyse the results. Finally, the creep behaviour of the specimens was estimated by the Zhou three-stage creep model. The results show that crumb rubber and trans-polyoctenamer significantly affected the parameters especially at high stress and temperatures. Consistent findings were observed for all permanent deformation parameters. Moreover, based on Zhou model, it was concluded that resistance to permanent deformation was improved by application of crumb rubber and trans-polyoctenamer.

  16. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Influence of free water content on the compressive mechanical behaviour of cement mortar under high strain rate · Jikai Zhou Xudong Chen Longqiang Wu Xiaowei Kan ... pp 111-117. Mechanical properties of concrete to cyclic uniaxial tensile loading using variable waveforms · YUZHI CHEN XUDONG CHEN JINGWU BU.

  17. A comparative study assessing a new tool for occluding ...

    African Journals Online (AJOL)

    0.630, p=0.068 and p=0.047, respectively) (Table 2). A comparative study assessing a new tool for occluding parenchymal blood flow during liver resection for hepatocellular carcinoma. S Zhou, X-J Xue, R-R Li, D-F Chen, W-Y Chen, G-X Liu, ...

  18. Inducing elliptically polarized high-order harmonics from aligned molecules with linearly polarized femtosecond pulses

    DEFF Research Database (Denmark)

    Etches, Adam; Madsen, Christian Bruun; Madsen, Lars Bojer

    2010-01-01

    A recent paper reported elliptically polarized high-order harmonics from aligned N2 using a linearly polarized driving field [X. Zhou et al., Phys. Rev. Lett. 102, 073902 (2009)]. This observation cannot be explained in the standard treatment of the Lewenstein model and has been ascribed to many...

  19. Characterization and thermal expansion of Sr2FexMo2−xO6 double ...

    Indian Academy of Sciences (India)

    in SFMO.21 The tolerance factor of SFMO double perovskite is given by t = rSr + rO ..... project OU-DST-PURSE-Scheme No. A.60. We express our ... Zhang L, Zhou Q, He Q and He T 2010 J. Power Sources 195. 6356. 12. Mostafa M F ...

  20. Molecular authentication of the traditional Tibetan medicinal plant ...

    African Journals Online (AJOL)

    Jane

    2011-07-25

    Jul 25, 2011 ... morphological characteristics (Gan and Yang, 1995;. Wang et al., 2003) and chemical profiles (Zhou et al.,. 2009). The identification guidelines of these methods are based on generic phenotypes such as appearance and chemical components, which are sensitive to intrinsic and extrinsic factors (Joshi et ...

  1. a legal assessment and review of the concept of sustainable

    African Journals Online (AJOL)

    OLAWUYI

    7 Farrell, A., Sustainability and Decision-making: The EPA's Sustainable ... Ardeleanu, G., Petrariu, R., Sustainable Development Strategies (2012), 54; .... 16 Elliott, J., A. An Introduction to Sustainable Development (2006), 8; Sneddon, Ch., .... taking a long-term perspective in the financial market (2012), 5; Lei, K., Zhou, S., ...

  2. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YUNJIAO ZHOU. Articles written in Journal of Genetics. Volume 96 Issue 6 December 2017 pp 993-1003 Research article. Association of lactase 13910 C/T polymorphism with bone mineral density and fracture risk: a meta-analysis · YOUGEN WU YINGHUA LI YUNQING CUI YUNJIAO ...

  3. Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

    Directory of Open Access Journals (Sweden)

    Li J

    2016-02-01

    Full Text Available Jingjing Li,1 Kan Chen,1 Sainan Li,1 Jiao Feng,1 Tong Liu,1 Fan Wang,1 Rong Zhang,1,2 Shizan Xu,1,2 Yuqing Zhou,1,3 Shunfeng Zhou,1,3 Yujing Xia,1 Jie Lu,1 Yingqun Zhou,1 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2The First Clinical Medical College of Nanjing Medical University, Nanjing, 3Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China Abstract: Liver fibrosis is a dynamic reversible pathological process in the development of chronic liver disease to cirrhosis. However, the current treatments are not administered for a long term due to their various side effects. Autophagy is initiated to decompose damaged or excess organelles, which had been found to alter the progression of liver fibrosis. In this article, we hypothesized that fucoidan from Fucus vesiculosus may attenuate liver fibrosis in mice by inhibition of the extracellular matrix and autophagy in carbon tetrachloride- and bile duct ligation-induced animal models of liver fibrosis. The results were determined using enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction, Western blotting, and immunohistochemical staining. Fucoidan from F. vesiculosus could inhibit the activation of hepatic stellate cells and the formation of extracellular matrix and autophagosomes, and its effect may be associated with the downregulation of transforming growth factor beta 1/Smads pathways. Fucoidan, as an autophagy and transforming growth factor beta 1 inhibitor, could be a promising potential therapeutic agent for liver fibrosis. Keywords: liver cirrhosis, hepatic stellate cells, bile duct ligation

  4. Deduction and Analysis of the Interacting Stress Response Pathways of Metal/Radionuclide-reducing Bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Jizhong [University of Oklahoma; He, Zhili [University of Oklahoma

    2010-02-28

    Project Title: Deduction and Analysis of the Interacting Stress Response Pathways of Metal/Radionuclide-reducing Bacteria DOE Grant Number: DE-FG02-06ER64205 Principal Investigator: Jizhong (Joe) Zhou (University of Oklahoma) Key members: Zhili He, Aifen Zhou, Christopher Hemme, Joy Van Nostrand, Ye Deng, and Qichao Tu Collaborators: Terry Hazen, Judy Wall, Adam Arkin, Matthew Fields, Aindrila Mukhopadhyay, and David Stahl Summary Three major objectives have been conducted in the Zhou group at the University of Oklahoma (OU): (i) understanding of gene function, regulation, network and evolution of Desulfovibrio vugaris Hildenborough in response to environmental stresses, (ii) development of metagenomics technologies for microbial community analysis, and (iii) functional characterization of microbial communities with metagenomic approaches. In the past a few years, we characterized four CRP/FNR regulators, sequenced ancestor and evolved D. vulgaris strains, and functionally analyzed those mutated genes identified in salt-adapted strains. Also, a new version of GeoChip 4.0 has been developed, which also includes stress response genes (StressChip), and a random matrix theory-based conceptual framework for identifying functional molecular ecological networks has been developed with the high throughput functional gene array hybridization data as well as pyrosequencing data from 16S rRNA genes. In addition, GeoChip and sequencing technologies as well as network analysis approaches have been used to analyze microbial communities from different habitats. Those studies provide a comprehensive understanding of gene function, regulation, network, and evolution in D. vulgaris, and microbial community diversity, composition and structure as well as their linkages with environmental factors and ecosystem functioning, which has resulted in more than 60 publications.

  5. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells

    Directory of Open Access Journals (Sweden)

    Li JP

    2015-02-01

    Full Text Available Jin-Ping Li,1,2 Yin-Xue Yang,3 Qi-Lun Liu,1 Zhi-Wei Zhou,2,4 Shu-Ting Pan,2,5 Zhi-Xu He,4 Xueji Zhang,6 Tianxin Yang,7 Si-Yuan Pan,8 Wei Duan,9 Shu-Ming He,10 Xiao-Wu Chen,11 Jia-Xuan Qiu,5 Shu-Feng Zhou2,41Department of Surgical Oncology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA; 3Department of Colorectal Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 4Guizhou Provincial Key Laboratory for Regenerative Medicine, Stem Cell and Tissue Engineering Research Center and Sino-US Joint Laboratory for Medical Sciences, Guiyang Medical University, Guiyang, Guizhou, People’s Republic of China; 5Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 6Research Center for Bioengineering and Sensing Technology, University of Science and Technology Beijing, Beijing, People’s Republic of China; 7Department of Internal Medicine, University of Utah and Salt Lake Veterans Affairs Medical Center, Salt Lake City, UT, USA; 8Department of Pharmacology, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 9School of Medicine, Deakin University, Waurn Ponds, VIC, Australia; 10Department of Obstetrics and Gynecology, Xiaolan People’s Hospital affiliated to Southern Medical University, Zhongshan, Guangdong, People’s Republic of China; 11Department of General Surgery, The First People’s Hospital of Shunde affiliated to Southern Medical University, Shunde, Foshan, Guangdong, People’s Republic of China Abstract: Danusertib (Danu is a pan-inhibitor of Aurora kinases and a third-generation breakpoint cluster region-Abelson murine leukemia viral oncogene homolog 1 (Bcr-Abl tyrosine kinase inhibitor

  6. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    CHEN AI-HUA1 MENG SU-CI2 ZHOU KAI1 WANG CONG-CONG1 ZHAO WEI2 WANG AI-JIAN2 QIAN JUN2. School of Chemistry & Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, People's Republic of China; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang ...

  7. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. QINGHUA NIE. Articles written in Journal of Genetics. Volume 90 Online resources 2011 pp e10-e20. Identification and characterization of the pig ABIN-1 gene and investigation of its association with reproduction traits · Meixia Fang Hongli Du Yongsheng Hu Xiaoning Zhou Hongjia ...

  8. Small Talk: A Missing Skill in the Chinese Communicative Repertoire

    Science.gov (United States)

    Cui, Xia

    2015-01-01

    There is growing evidence that social interactions at work with local colleagues present a real challenge for Chinese immigrants to Australia (e.g. Tomazin, 2009; Zhou, Windsor, Coyer, & Theobald, 2010), often leaving them feeling defeated and despairing, and the Australians puzzled or affronted. Seeking to understand the nature, origin, and…

  9. Connections between the Radio, Optical and Soft X-ray Luminosities ...

    Indian Academy of Sciences (India)

    for Flat-Spectrum Radio Quasars. Zhi-Fu Chen1, Cai-Juan Pan1,∗, You-Bing Li2 & Yu-Tao Zhou3. 1Department of Physics and Telecommunication Engineering of Baise University,. Baise 533000, China. 2Guangzhou City Construction College, Guangdong 510925, China. 3Center for Astrophysics, Guangzhou University, ...

  10. The Mechanism by which Neurofibromin Suppresses Tumorigenesis

    Science.gov (United States)

    2013-02-01

    et al., 2011; Taichman et al., 2002; Zeelenberg et al., 2003; Zhou et al., 2002), as well as non-Hodgkin’s lymphoma (Bertolini et al., 2002), and...underlie the unique pattern of optic glioma growth in neurofibromatosis type Cancer Res 67, 8588-8595. Zeelenberg , I.S., Ruuls-Van Stalle, L., and

  11. Equilibrium Price Dispersion in a Matching Model with Divisible Money

    NARCIS (Netherlands)

    Kamiya, K.; Sato, T.

    2002-01-01

    The main purpose of this paper is to show that, for any given parameter values, an equilibrium with dispersed prices (two-price equilibrium) exists in a simple matching model with divisible money presented by Green and Zhou (1998).We also show that our two-price equilibrium is unique in certain

  12. Proteomic identification of CIB1 as a potential diagnostic factor in ...

    Indian Academy of Sciences (India)

    Proteomic identification of CIB1 as a potential diagnostic factor in hepatocellular carcinoma. Tong Junrong Zhou Huancheng H E Feng Gao Yi Yang Xiaoqin Luo Zhengmao Zhang Hong Zeng Jianying Wang Yin Huang Yuanhang Zhang Jianlin Sun Longhua He Guolin. Articles Volume 36 Issue 4 September 2011 pp 659- ...

  13. Proactive and Preventive Coping in Adjustment to College

    Science.gov (United States)

    Gan, Yiqun; Hu, Yueqin; Zhang, Yiwen

    2010-01-01

    The current study compared the relative importance of proactive coping and preventive coping in the adjustment to university life among 403 freshmen at a Chinese university and evaluated the function of proactive coping in the stress process. Participants completed the Future-Oriented Coping Inventory (Gan, Yang, Zhou, & Zhang, 2007), the…

  14. Effect of ultrasonic specific energy on waste activated sludge ...

    African Journals Online (AJOL)

    USER

    2010-03-22

    Mar 22, 2010 ... Yuanyuan Yan, Leiyu Feng*, Chaojie Zhang, Hongguang Zhu and Qi Zhou. State Key ... soluble chemical oxygen demand; TCOD, total chemical oxygen demand ... studied as well as their effects on the characteristics of sludge. .... universal liquid module (ULM) which could detect particle size from. 0.04 up ...

  15. Determination of antioxidant and α-glucosidase inhibitory activities ...

    African Journals Online (AJOL)

    ajl yemi

    2011-10-14

    Oct 14, 2011 ... 2Majors in Plant Resource Sciences and Environment, College of Applied Life ... Carlsen and co-workers (2010) hypothesized that ... #These authors contributed equally to this work. ... 2diabetes mellitus (T2DM) is a metabolic disease that ... drinks in China, Korea and Japan (Zhou and Yang, 2009).

  16. Marine Science

    African Journals Online (AJOL)

    Copy Editor Timothy Andrew. Published ... 2007; Zhou et al., 2009) and they play an important role in the ... At both sites, zonal variation in TMPB was evident with significantly higher C-biomass closer to ... ton is considered to be an essential parameter in eco- systems ...... logical significance of toxic marine dinoflagellates.

  17. Effects of palm oil mill effluent (POME) anaerobic sludge from 500 m ...

    African Journals Online (AJOL)

    USER

    2010-04-19

    Apr 19, 2010 ... in the country (Lau et al., 2008). Thus, the ... within 80 days with final C/N ratio of 12.5. .... C/N ratio of pressed shredded EFB was 54.4 with carbon ..... Wong JWC, Mak KF, Chan NW, Lam A, Fang M, Zhou LX, Wu QT, Liao.

  18. Improving planting pattern for intercropping in the whole production ...

    African Journals Online (AJOL)

    DR. NJ TONUKARI

    2012-04-26

    Apr 26, 2012 ... vegetable for the people or to enrich biodiversity of rubber plantations in the area of hundred-miles rubber ..... Influence of rubber canopy on intercrop productivity. Trans. Malaysian Soc. Plant Physiol. 2: 75-79. Lin Weifu, Zhou Zhongyu, Huang Shoufeng (1999). A review and prospect of intercropping in ...

  19. Ganoderic acid B's influence towards the therapeutic window of ...

    African Journals Online (AJOL)

    9. Hempel C, Norenberg W, Sobottka H, Urban N, Nicke. A, Fischer W, Schaefer M. The phenothiazine-class an- tipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor. Neuropharmacology 2013; 75:365-379. 10. Song H, Tao Y, Zhang CZ, Zhou YD. Comparison.

  20. Heat capacity measurements on Ybx Gd2–x Zr2 O7 (x= 0, 1, 2 ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 32; Issue 6. Heat capacity measurements on YbGd2–Zr2O7 ( = 0, 1, 2) ceramics by differential scanning calorimetry. Zhan-Guo Liu Jia-Hu Ouyang Yu Zhou. Ceramics and Glasses Volume 32 Issue 6 December 2009 pp 603-606 ...

  1. Photosynthetic induction in leaves of two cucumber genotypes ...

    African Journals Online (AJOL)

    user

    2011-03-21

    Mar 21, 2011 ... 2 with low light-sensitivity were used to study the response of gas exchange, ..... LL-JY2. LL-Deltastar. B. 0. 50. 100. 150. 200. 250. 300. 350. 0. 6. 12. 18 ..... Zhou YH, Yu JQ, Mao WH, Huang LF, Song XS, Nogués S (2006).

  2. Education and Social Selection in Ancient China: Semantics, Conceptual Transformation and Social Change

    Science.gov (United States)

    Wu, Meiyao

    2015-01-01

    This paper investigates the transformation in the Zhou dynasty China (1046-256 BC) of the concept of education in relation to the process of social selection, which concerns the distribution both of knowledge and of social ranks. An approach in terms of historical semantics, mainly influenced by Luhmannian sociological theory with some reference…

  3. Mapping of genes for flower-related traits and QTLs for flowering ...

    Indian Academy of Sciences (India)

    Mapping of genes for flower-related traits and QTLs for flowering time in an interspecific population of Gossypium hirsutum × G. darwinii. Shuwen Zhang, Qianqian Lan, Xiang Gao, Biao Yang, Caiping Cai, Tianzhen Zhang and Baoliang Zhou. J. Genet. 95, 197–201. Table 1. Loci composition and recombination distances of ...

  4. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Journal of Genetics; Volume 95; Issue 1. Novel NPHS1 gene mutations in a Chinese family with congenital nephrotic syndrome. Fengjie Yang Yaxian Chen Yu Zhang Liru Qiu Yu Chen Jianhua Zhou. Research Note Volume 95 Issue 1 March 2016 pp 161- ...

  5. Biisofraxidin on Apoptosis of Human Gastric Cancer BGC-823 Cells

    African Journals Online (AJOL)

    Wu et al. Trop J Pharm Res, October 2015; 14(10): 1803. Tropical Journal of Pharmaceutical Research ... Jian-Tao Wu1,2*, She-Min Lv1, Chun-Hui Lu1, Jun Gong1 and Jian-Bo An3 ..... Zhu AK, Zhou H, Xia JZ, Jin HC, Wang K, Yan J, Zuo JB,.

  6. Type II Superlattice as Low-Temperature Peltier Refrigerator (4K-150K)

    Science.gov (United States)

    2012-02-29

    SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON a. REPORT...Chuanle  Zhou,  Seda  Ogrenci  Memik,  M.  Grayson,  " IOTA :  Towards   an  integrated  on-­‐chip  thermocouple  array

  7. Research general situation of Silkworm pathology in China

    African Journals Online (AJOL)

    Administrator

    2011-12-12

    Dec 12, 2011 ... significant impact on the stability of the sericulture, also on our harmonious society, so that studies on ..... material in the aggregation the formation of dark brown spots. (Zhou et al., 1997). Significant lesions in the .... far away from the brick, cement plants and other exhaust emissions serious areas and ...

  8. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Acupuncture in Treating Hepatic Fibrosis: A Review with Recommendation for Future Studies · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J Zhou, Y Liang, XM Lin, RJ Ma, JQ Fang, 452-458. http://dx.doi.org/10.4314/ajtcam.v9i4.1 ...

  9. A focus on the features of polyaniline nanofibres prepared via ...

    Indian Academy of Sciences (India)

    2018-02-05

    Feb 5, 2018 ... volume [10], solubility [11], electrical conductivity [12] and ... (surfactants [32], micelles [22,33,34], liquid crystals [35], ... processability and doping properties of PANI could be further ... reaction is completed as indicated by no further formation of ...... [49] Yang Z, Wu J, Yang Y, Zhou X and Xie X 2008 Chem.

  10. Genotype and Haplotype Analysis of ABCB1 at 1236, 2677 and ...

    African Journals Online (AJOL)

    Genetica Sinica 2005; 33: 93-104. 2. Zhou SF. Structure, function and regulation of P- glycoprotein and its clinical relevance in drug disposition. Xenobiotica 2008; 38(7-8): 802-832. 3. Ishikawa T, Onishi Y, Hirano H, Oosumi K, Nagakura M ,. Tarui S. Pharmacogenomics of drug transporters: a new approach to functional ...

  11. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Our results suggest that black holes in radio galaxies are rapidly spinning. Volume 35 Issue 3 September 2014 pp 357-362 Part IV: Emission Models and Theory. What Governs Lorentz Factors of Jet Components in Blazars? Xinwu Cao Bo Chai Ming Zhou Minfeng Gu · More Details Abstract Fulltext PDF.

  12. Fulltext PDF

    Indian Academy of Sciences (India)

    The paper “Anaerobic oxidation of methane in coastal sediment from Guishan Island. (Pearl River Estuary), South China Sea” by Zijun Wu, Huaiyang Zhou, Xiaotong Peng,. Nan Jia, Yuhong Wang and Linxi Yuan (Journal of Earth System Science, Volume 117,. No. 6, pages 935–944, December 2008) overlaps in scope and ...

  13. Implicit-shifted Symmetric QR Singular Value Decomposition of 3x3 Matrices

    Science.gov (United States)

    2016-04-01

    Graph 33, 4, 138:1– 138:11. TREFETHEN, L. N., AND BAU III, D. 1997. Numerical linear algebra , vol. 50. Siam. XU, H., SIN, F., ZHU, Y., AND BARBIČ, J...matrices with minimal branching and elementary floating point operations. Tech. rep., University of Wisconsin- Madison. SAITO, S., ZHOU, Z.-Y., AND

  14. Research Article

    African Journals Online (AJOL)

    2016-06-09

    Jun 9, 2016 ... The process of estimation occurs in two stages: in the first stage, the high orders of the signal are estimated ..... In this section we describe the simulation using the theory in the previous section on. MATLAB software. .... [20]Zhou G and Giannakis G. B. On estimating random amplitude modulated harmonics.

  15. “La Diplomacia Secreta”: la participación de Colombia en el conflicto entre Perú y España por las islas guaneras

    Directory of Open Access Journals (Sweden)

    Yoer Javier Castaño Pareja

    2013-01-01

    Full Text Available During the fourth presidency of General Tomás Cipriano de Mosquera, the Colom- bian government interfered in a diplomatic incident which apparently violated the neutrality that this country had promised to maintain during the war between Peru and Spain in the 1865-1866 period as a consequence of the Hispanic inva- sion of guano producing islands. In this paper some causes that made a few mem- bers of the Colombian government to decide to support Peru¿s war effort without the consent of Congress are explored. Subsequently, this research identifies the features and characteristics of diplomatic positions that in that time were in con- flict within the Colombian government and that marked the course of diploma- tic relations with the neighbouring countries, in an international political context that was characterized by European invasions on some Latin American territories.

  16. Influence of Ce 0.68 Zr 0.32 O 2 solid solution on depositing ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 29; Issue 1. Influence of Ce0.68Zr0.32O2 solid solution on depositing -alumina washcoat on FeCrAl foils. Mei-Qing Shen Li-Wei Jia Wen-Long Zhou Jun Wang Ying Huang. Composites Volume 29 Issue 1 February 2006 pp 73-76 ...

  17. Rapid growth of nanotubes and nanorods of würtzite ZnO through ...

    Indian Academy of Sciences (India)

    Administrator

    report here on the synthesis of ZnO nanorods and nano- tubes from a ..... Hu Y, Zhou X, Han Q, Cao Q and Huang Y 2003 Mater. Sci. ... Lao J Y, Huang J Y, Wang D Z and Ren Z F 2003 Nano Lett. 3. 235 ... Xing Y J et al 2003 Appl. Phys. Lett.

  18. Effects of ridge and furrow rainfall harvesting system on Elymus ...

    African Journals Online (AJOL)

    ARL

    2012-05-10

    May 10, 2012 ... A ridge-furrow rainfall harvesting system (RFRHS) was designed to increase the available soil water for .... The solar energy passed through the plastic-film and heated up the air and the surface soil of ridge and then the heat was trapped by the greenhouse effect (Zhou et al., 2009). Meanwhile, the.

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 151 - 200 of 1250 ... J Zhou, F Qu. Vol 10, No 2 (2013), Analysis of volatile compounds of Malaysian Tualang (Koompassia excelsa) honey using gas chromatography mass spectrometry, Abstract PDF. SMS Nurul, SH Gan, AS Halim, NSM Shah, SH Gan, HA Sukari. Vol 10, No 4 (2013), Analysis on 113 cases of adverse ...

  20. Core Gene Expression and Association of Genotypes with Viral ...

    African Journals Online (AJOL)

    HP

    Fukutomi T, Zhou Y, Kawai S, Eguchi H, Wands JR, Li J. Hepatitis C virus core protein stimulates hepatocyte growth: correlation with up regulation of wnt-1 expression. Hepatology. 2005; 41: 1096-1105. 5. Raja NS, Janjua KA. Epidemiology of hepatitis C virus infection in Pakistan. J. Microbiol. Immunol. Infect. 2008; 41: 4–8.

  1. African Journal of Biotechnology - Vol 11, No 14 (2012)

    African Journals Online (AJOL)

    DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. HD Ding, HJ Zhang, XH Zhu, H Liu, JS Liang, B Lu, 3259-3269 ... DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Y Hanying, X Wei, G Xingxi, 3370-3378 ... FULL TEXT DOWNLOAD FULL TEXT. J Zhang, YC Huang, Q Zhang, ZP Hong, YC Zhou, WL Chen, 3388-3393 ...

  2. Effects of various forms of lipopolysaccharide on the expression of ...

    African Journals Online (AJOL)

    Jane

    2011-10-05

    Oct 5, 2011 ... Lan-jun Bai1, Wings TY Loo2,3,4*, Yiding Dou4, Min Wang5, Hao Liang5, Mary NB Cheung3,4,6 ... The levels of lactate dehydrogenase (LDH), N-terminal pro ...... Li G-R, Sun H-Y, Chen J-B, Zhou Y, Tse H-F, Lau C-P (2009).

  3. Early Chinese History: The Hundred Schools Period. China's Golden Age of Philosophy. A Unit of Study for Grades 9-12.

    Science.gov (United States)

    Huff, Lehn; Dube, Clayton

    In this unit students examine the four most influential Chinese philosophical traditions developed during the Zhou period (roughly 6th-3rd centuries B.C.E.). The four philosophies students study include: (1) Confucianism; (2) Mohism; (3) Daoism (Taoism); and (4) Legalism. In three lessons, students compare the ideas of these schools and explore…

  4. Spray and Combustion of Gelled Hypergolic Propellants for Future Rocket and Missile Engines

    Science.gov (United States)

    2014-08-13

    Park City, Utah, May 2013. [28]. L. S. Rothman, D. Jacquemart, A. Barbe, D. Chris Benner, M. Birk, L. R. Brown, M. R. Carleer, J. C. Chackerian, K...2371. [81]. J. Higgins , X. Zhou, R. Liu, T. T. S. Huang, “Theoretical Study of Thermal Decomposition Mechanism of Oxalic Acid”, J. Phys. Chem. A

  5. [Textual research on circulation of the Ming edition of Li Heng's Xiu zhen fang (Pocket Formulary)].

    Science.gov (United States)

    Yang, Jinping; Liu, Peng; Lu, Mingjing; Lu, Xing; Li, Shaolin; Jin, Xiumei

    2015-03-01

    Xiu zhen fang (Pocket Formulary) is a recipe book of the Ming Dynasty, inspired and managed by Zhu Su, compiled by Li Heng of liangyisuo (good physician house) in Zhou wangfu (Zhou's royal palace). The book was compiled and published twice during the reigns of the Hongwu and Yongle Emperors of the Ming Dynasty. Because of its high practicability, there were some editions in circulation, and the book was published several times only in the Ming Dynasty. At present, the earliest extanteditionwas the little character version of Yongle, and the version in the 4(th) year of Zhengde Emperor of the Ming Dynasty was a reprinting edition based on the Yongle edition, sharingthe same edition system. Most of the editions appeared after the reign of Zhengtong Emperor of the Ming Dynasty, titled by "kui ben (head version)" and "da quan (complete edition)" were the editionspublished in the local bookshops, which had rather distinct differences from the Yongle edition system not only in the its format but also in its contents.

  6. The Marotto Theorem on planar monotone or competitive maps

    International Nuclear Information System (INIS)

    Yu Huang

    2004-01-01

    In 1978, Marotto generalized Li-Yorke's results on the criterion for chaos from one-dimensional discrete dynamical systems to n-dimensional discrete dynamical systems, showing that the existence of a non-degenerate snap-back repeller implies chaos in the sense of Li-Yorke. This theorem is very useful in predicting and analyzing discrete chaos in multi-dimensional dynamical systems. Yet, besides it is well known that there exists an error in the conditions of the original Marotto Theorem, and several authors had tried to correct it in different way, Chen, Hsu and Zhou pointed out that the verification of 'non-degeneracy' of a snap-back repeller is the most difficult in general and expected, 'almost beyond reasonable doubt', that the existence of only degenerate snap-back repeller still implies chaotic, which was posed as a conjecture by them. In this paper, we shall give necessary and sufficient conditions of chaos in the sense of Li-Yorke for planar monotone or competitive discrete dynamical systems and solve Chen-Hsu-Zhou Conjecture for such kinds of systems

  7. Convergence of an implicit iteration process for a finite family of asymptotically quasi-nonexpansive mappings in convex metric spaces

    Directory of Open Access Journals (Sweden)

    Gurucharan Singh Saluja

    2010-01-01

    Full Text Available In this paper, we give some necessary and sufficient conditions for an implicit iteration process with errors for a finite family of asymptotically quasi-nonexpansive mappings converging to a common fixed of the mappings in convex metric spaces. Our results extend and improve some recent results of Sun, Wittmann, Xu and Ori, and Zhou and Chang.

  8. Amplified fragment length polymorphism (AFLP) and genealogy ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-06-07

    Jun 7, 2010 ... Pang CY, Du XM, Ma ZY (2006). Evaluation of the introgressed lines and screening for elite germplasm in Gossypium, Chin. Sci. Bull. 51(1):. 304-312. Pieter V, Rene H, Marjo B (1995). AFLP: a new technique for DNA fingerprinting. Nucleic Acids Res. 23(21): 4407-4414. Qian SY, Huang JQ, Zhou BL, Peng ...

  9. Embedding relations connected with strong approximation of Fourier ...

    Indian Academy of Sciences (India)

    ing only odd functions and a set of functions defined via the strong means of Fourier series of odd continuous functions. We establish an improvement of a recent theorem of Le and Zhou [Math. Inequal. Appl. 11(4) (2008) 749–756] which is a generalization of Tikhonov's results [Anal. Math. 31 (2005) 183–194]. We also ...

  10. Lin-Na and Yong-Xiu Afr J Tradit Complement Altern Med. (2014) 11 ...

    African Journals Online (AJOL)

    cadewumi

    Evaluation of anti-athletic fatigue activity of Schizandra chinensis aqueous extracts in mice. Afr J Pharm Pharmacol 3: 593-597. 4. Cao, Y., Hu, Y., Liu, P., Zhao, H.X., Zhou, X.J., and Wei, Y.M. (2012). Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running ...

  11. Genetics Home Reference: otulipenia

    Science.gov (United States)

    ... Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai WL, Kuehn HS, Wang H, Yang D, Park YH, Ombrello AK, Blake M, Romeo T, Remmers EF, Chae JJ, Mullikin JC, Güzel F, Milner JD, Boehm M, Rosenzweig SD, Gadina M, Welch SB, Özen S, Topaloglu R, Abinun M, Kastner DL, Aksentijevich I. Biallelic hypomorphic ...

  12. Antioxidant and Anti-proliferative Activities of Flavonoids from ...

    African Journals Online (AJOL)

    significant growth inhibitory effect on RKO cells with IC50 of 39.08 μmol/L and 17.68 μmol/L, respectively ..... YJ.. Essential oil from rhizomes of Ligusticum chuanxiong induces apoptosis in hypertrophic scar ... Liu H, Mou Y, Zhao J, Wang J, Zhou L, Wang M, Wang. D, Han J, Yu Z, Yang F. Flavonoids from Halostachys.

  13. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yan-Qin Xu Guo-Yan Wei Yin Zhou Fei Ge Guang-Ming Luo · More Details Fulltext PDF. pp e25-e28. Abundance and characteristics of microsatellite markers in Gansu zokor (Eospalax cansus), a fossorial rodent endemic to the Loess plateau, China · Junhu Su Limin Hua Jing Wang Dianne M. Gleeson Yanming Wei Robyn ...

  14. Role of Polymerase Gamma Mutations in Breast Tumorigenesis

    Science.gov (United States)

    2010-08-01

    triggers steatosis in mouse liver. J Pharmacol. Exp. Ther 2007;321:526–535. [PubMed: 17277197] 21. Yu M, Zhou Y, Shi Y, Ning L, Yang Y, Wei X, et al...encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion. Nat. Genet 2006;38:570–575. [PubMed

  15. 50 Detecting adenosine triphosphatase 6 point mutations that may ...

    African Journals Online (AJOL)

    mutations at codons for the key residues Lys 260, Leu263, Gln266, Ser769 .... agarose gel and visualized under UV transillumination after treatment with ..... Li, W., Mo, W., Shen, D., Sun, L., Wang, J., Lu, S., Gitschier, J.M. & Zhou, B. (2005) Yeast ... Nagamune, K., Beatty, W.L., & Sibley, D. (2007) Artemisinin induces Calcium ...

  16. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Combination of acupuncture and Chinese medicinal herbs in treating model rats with Polycystic Ovary Syndrome · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. R-J Ma, J Zhou, J-Q Fang, D-H Yang, F Qu. http://dx.doi.org/10.4314/ajtcam.v8i4.3 ...

  17. Emissive lead(II) benzenedicarboxylate metal-organic frameworks

    Indian Academy of Sciences (India)

    Abdul Malik P Peedikakkal

    2018-04-16

    Apr 16, 2018 ... Jang E, Jun S, Jang H, Lim J, Kim B and Kim Y 2010. White-light-emitting ... 2837; (b) Li Y-F, Wang D, Liao Z, Kang Y, Ding. W-H, Zheng X-J, Jin L-P 2016 .... Zuo J-L and Zhou H-C 2007 Synthesis and Characteri- zations of a ...

  18. The Flynn Effect and Its Critics: Rusty Linchpins and "Lookin' for g and Gf in Some of the Wrong Places"

    Science.gov (United States)

    McGrew, Kevin S.

    2010-01-01

    The consensus of most intelligence scholars is that the Flynn effect (FE) is real, IQ test batteries are now routinely restandardized on a regular basis. A cornerstone in Flynn's explanation of the FE is his analysis of select Wechsler subtest scores across time. The featured articles by Kaufman and Zhou, Zhu, and Weiss question whether Flynn's…

  19. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Hui Shen. Articles written in Bulletin of Materials Science. Volume 30 Issue 2 April 2007 pp 101-104 Single Crystals. Piezoelectric properties of Sr3Ga2Ge4O14 single crystals · Anhua Wu Jiayue Xu Juan Zhou Hui Shen · More Details Abstract Fulltext PDF. A new piezoelectric ...

  20. Influences of the disease resistance conferred by the individual ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-05

    Oct 5, 2009 ... eleven rice blast (Wang et al., 1999; Bryan et al., 2000;. Qu et al., 2006; Chen et al., 2006; Zhou et al., 2006; Liu et al., 2007; Lin et al., ..... Lee SK, Song MY, Seo YS, Kim HK, Ko S, Cao PJ, Suh JP, Yi G, Roh. JH, Lee S, An G, ...

  1. Geotourism Aspects of the Lufeng Dinosaur National Geopark in Yunnan Province, China

    Directory of Open Access Journals (Sweden)

    Daněk Tomáš

    2016-03-01

    Full Text Available The Lufeng Dinosaur National Geopark in Yunnan province, China, is important part of geoheritage with a great scientific and aesthetic value. The area has been under scientific research since 1938 when the first dinosaur fossils were discovered here by geologist Bian Meinian and technician Wang Cunyi. Professor Yang announced the discovery of new early Jurassic herbivore prosauropod by Lufeng in 1941, which he gave the name Lufengosaurus huenei. In 2004, the area was listed as the China`s National Geopark. It was opened for visitors in 2008. Besides the high scientific value, the geopark is also an important resource for science based and educational tourism. This paper briefly introduces the history of scientific research, the basic geology of the site and the most important fossils discovered here. The main characteristics, geodiversity, and geotourism of fossil geoheritage in the area are discussed here.

  2. Zhou et al., Afr J Tradit Complement Altern Med. (2010) 7(4):339-349

    African Journals Online (AJOL)

    USER

    Thirdly, pharmacokinetics analysis of Scutellaria baicalensis and Curcuma .... All the plasma samples were stored at −20°C until analysis. ... After centrifugation at 3,000 rpm for 10 min, the supernatant was filtered through a 0.45 μm membrane filter unit. ..... traditional Chinese herbs and vegetables for chemoprevention.

  3. Zhou et al., Afr J Tradit Complement Altern Med. (2015) 12(4):87-95 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    containing 10 rats: (1) I/R-ethanol group (IRI), in which the rats were .... Wy14643 Pretreatment Alleviated Liver Pathological Changes in Liver I/R Injury .... IRI in myocardial and cerebral by suppressing inflammation(Yeh CH,2006; Collino M,.

  4. Horizontal subsurface flow constructed wetlands for mitigation of ...

    African Journals Online (AJOL)

    2008-12-22

    Dec 22, 2008 ... Results indicated that 39% of the total initially added amount of ametryn ... characteristics (Table 1), may result in the detection of poten- ... Water solubility at 20oC (g∙m-3) 204 ... culture, part of the resident liquid in CWs was lost, therefore ..... LIN T, WEN y, JIANG L, LI J, yANG S and ZHOu Q (2008) Study.

  5. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. F Wang. Articles written in Bulletin of Materials Science. Volume 34 Issue 5 August 2011 pp 1033-1037. Synthesis of Mn-doped CeO2 nanorods and their application as humidity sensors · C H Hu C H Xia F Wang M Zhou P F Yin X Y Han · More Details Abstract Fulltext PDF.

  6. Identification of Two New Protective Pre-erythrocytic Malaria Vaccine Antigen Candidates

    Science.gov (United States)

    2011-01-01

    Anthony R, Grainger M, Haynes J, Moch J, Muster N, Sacci J, Tabb D, Witney A, Wolters D, Wu Y, Gardner M, Holder A, Sinden R, Yates J, Carucci D: A...proteomic view of the Plasmodium falciparum life cycle. Nature 2002, 419:520-526. 16. LeRoch D, Zhou Y, Blair P, Grainger M, Moch J, Haynes J, De La Vega P

  7. Zhong et al., Afr J Tradit Complement Altern Med. (2014) 11(1):1-14

    African Journals Online (AJOL)

    cadewumi

    Yunqing Zhong*1, Xiufeng Wang2, Guanglan Xu,1, Bing Mao3, Wei Zhou3, Jie Min3, Hongli Jiang3, Xiang Diao4 , ..... due to COPD exacerbations, and 1 experienced a cerebrovascular accident. ..... the body (Makino T., 2005b; Hong et al., 2011). ... An, X., Zhang, A.L., Yang, A.W., Lin, L., Wu, D., Guo, X., Shergis, J.L., Thien, ...

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. C H Xia. Articles written in Bulletin of Materials Science. Volume 34 Issue 5 August 2011 pp 1033-1037. Synthesis of Mn-doped CeO2 nanorods and their application as humidity sensors · C H Hu C H Xia F Wang M Zhou P F Yin X Y Han · More Details Abstract Fulltext PDF.

  9. The Anatomy of the Resource Curse: Predatory Investment in Africa’s Extractive Industries

    Science.gov (United States)

    2015-05-01

    that expose corruption and spearhead campaigns to enhance transparency and accountability. However, censorship and interference by those in power...previously served as Zimbabwe’s Acting High Commissioner in Malaysia and later sat on Zimbabwe’s Grain Marketing Board; and Pritchard Zhou, a Zimbabwean...states, reporters and nongovernmental organizations frequently face intimidation, censorship , imprisonment, and violence.420 Such policies or actions

  10. A system-level mechanistic investigation of traditional Chinese ...

    African Journals Online (AJOL)

    Xiao-Hong Gu* ... targets related to lung and stomach diseases were searched and screened to avoid duplication. ... Liu et al. Trop J Pharm Res, August 2017; 16(8): 1910. On account of this deficiency in knowledge, ..... Ru J, Li P, Wang J, Zhou W, Li B, Huang C, Li P, Guo Z, ... Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2013;.

  11. Wh-Questions, Universal Statements and Free Choice Inferences in Child Mandarin.

    Science.gov (United States)

    Huang, Haiquan; Zhou, Peng; Crain, Stephen

    2017-11-16

    This study investigated 5-year-old Mandarin-speaking children's comprehension of wh-questions, universal statements and free choice inferences. Previous research has found that Mandarin-speaking children assign a universal interpretation to sentences with a wh-word (e.g., shei 'who') followed by the adverbial quantifier dou 'all' (Zhou in Appl Psycholinguist 36:411-435, 2013). Children also compute free choice inferences in sentences that contain a modal verb in addition to a wh-word and dou (Zhou, in: Nakayama, Su, Huang (eds.) Studies in Chinese and Japanese language acquisition: in honour of Stephen Crain. John Benjamins Publishing Company, Amsterdam, pp 223-235, 2017). The present study used a Question-Statement Task to assess children's interpretation of sentences containing shei + dou, both with and without the modal verb beiyunxu 'was allowed to', as well as the contrast between sentences with shei + dou, which are statements for adults, versus ones with dou + shei, which are wh-questions for adults. The 5-year-old Mandarin-speaking child participants exhibited adult-like linguistic knowledge of the semantics and pragmatics of wh-words, the adverbial quantifier dou, and the deontic modal verb beiyunxu.

  12. Study on the pre-qin pottery and proto-porcelain from boluo county, Guangdong province with INAA

    International Nuclear Information System (INIS)

    Wang Jianping; Chen Tiemei

    2003-01-01

    Seventy-seven pottery and proto-porcelain sherds collected from Meihuadun, Yingang and Henglingshan sites of Boluo County, Guangdong Province were studied with INAA. These sherds are of Western Zhou to Warring States Period. Concentrations of 27 elements were measured, then principal component analysis and other statistical procedures were applied to the data set in order to classify these sherds. This study shows: (1) Though these 3 archaeological sites are located close to each other within an area of about 1000 km 2 , ancient potters of these sites might use raw materials of different origins for pottery production, as pottery sherds of these 3 sites show different chemical compositions. Such differentiation is also observed for the proto-porcelain samples, indicating that proto-porcelain samples found at Meihuadun and Henglingshan might be of different provenance; (2) In each site during the Western Zhou to Spring-Autumn Period the same raw material was used for both hard pottery and soft pottery manufacturing, while during the Warring States Period no similarity in chemical compositions was observed between hard pottery and soft pottery samples. It is wondered if this phenomenon means an advancement of ceramic technology

  13. [Herbological studies on Chinese crude drug Ma-huang. Part 1-On the botanical origin of Ma-huang in ancient China and the origin of Japanese Ma-huang].

    Science.gov (United States)

    Yoshizawa, Chieko; Kitade, Makiko; Mikage, Masayuki

    2005-01-01

    The botanical origin of a Chinese crude drug Ma-huang in ancient China and the origin of Japanese Ma-huang were herbologically studied. The results showed that the plants of Ephedra sinica Stapf, E. intermedia Schrenk & C. A. Meyer and E. equisetina Bunge were used as Ma-huang in China, and the first species was considered to be of high quality. The characters of Mao-zhou Ma-huang and Tong-zhou Ma-huang printed in Tu-jing-ben-cao, published in the Song Dynasty in China, were identified as E. likiangensis Florin and E. intermedia, respectively, and both species were recognized as excellent Ma-huang in the Ming Dynasty. The word origin of Katsune-kusa, the Japanese name for Ma-huang in the Heian Era, was etymologically considered as meaning the plant having reddish brown roots. In Japan, the plant of Equisetum ramosissimum Desf. var.japonicum Milde, of the family Equisetaceae, was substituted for Ma-huang in the middle of Edo Era, and it was designated that this action was based on the confusion of Ephedra plants and Equisetum plants those days in China.

  14. A Stochastic Maximum Principle for Risk-Sensitive Mean-Field Type Control

    KAUST Repository

    Djehiche, Boualem; Tembine, Hamidou; Tempone, Raul

    2015-01-01

    In this paper we study mean-field type control problems with risk-sensitive performance functionals. We establish a stochastic maximum principle (SMP) for optimal control of stochastic differential equations (SDEs) of mean-field type, in which the drift and the diffusion coefficients as well as the performance functional depend not only on the state and the control but also on the mean of the distribution of the state. Our result extends the risk-sensitive SMP (without mean-field coupling) of Lim and Zhou (2005), derived for feedback (or Markov) type optimal controls, to optimal control problems for non-Markovian dynamics which may be time-inconsistent in the sense that the Bellman optimality principle does not hold. In our approach to the risk-sensitive SMP, the smoothness assumption on the value-function imposed in Lim and Zhou (2005) needs not be satisfied. For a general action space a Peng's type SMP is derived, specifying the necessary conditions for optimality. Two examples are carried out to illustrate the proposed risk-sensitive mean-field type SMP under linear stochastic dynamics with exponential quadratic cost function. Explicit solutions are given for both mean-field free and mean-field models.

  15. The Relationship between Daoist Rituals and Theatrical Performance: The Case of Xianggong Tapeng in Puxian Theater

    Directory of Open Access Journals (Sweden)

    Lijuan Zhang

    2014-10-01

    Full Text Available Daoism is a traditional Chinese religion. Daoism has had a deep and pervasive impact on the lives of China’s peoples. Chinese theatrical performances were often integrated with religious activities, thereby gradually giving rise to many forms of popular drama that are deeply inflected with religious overtones. Xianggong Tapeng (相公踏棚, Xianggong stamps the shed is one component of Puxian opera’s rites for stage cleaning that is closely linked with Daoist thought. First, Xianggong is both a theatrical spirit within Puxian opera and a member of the Daoist pantheon. Second, the lyric “luo li lian” featured in Xianggong Tapeng bears a remarkable resemblance to the two Daoist spells Yuanshuai Zhou (元帥咒, Incantation of Yuanshuai and Xiangmo Zhou (降魔咒, Incantation for Subduing Demons. This is due to the fact that traditional Daoist verse often features phrases such as “luo li lian”. Moreover, the stage cleaning rites that are characteristic of Puxian opera share many similarities with Daoist altar purification rites. A detailed investigation and comparison reveal that Xianggong Tapeng is an adaptation of the Daoist altar purification rite to the needs of popular custom and theatrical performance.

  16. A Stochastic Maximum Principle for Risk-Sensitive Mean-Field Type Control

    KAUST Repository

    Djehiche, Boualem

    2015-02-24

    In this paper we study mean-field type control problems with risk-sensitive performance functionals. We establish a stochastic maximum principle (SMP) for optimal control of stochastic differential equations (SDEs) of mean-field type, in which the drift and the diffusion coefficients as well as the performance functional depend not only on the state and the control but also on the mean of the distribution of the state. Our result extends the risk-sensitive SMP (without mean-field coupling) of Lim and Zhou (2005), derived for feedback (or Markov) type optimal controls, to optimal control problems for non-Markovian dynamics which may be time-inconsistent in the sense that the Bellman optimality principle does not hold. In our approach to the risk-sensitive SMP, the smoothness assumption on the value-function imposed in Lim and Zhou (2005) needs not be satisfied. For a general action space a Peng\\'s type SMP is derived, specifying the necessary conditions for optimality. Two examples are carried out to illustrate the proposed risk-sensitive mean-field type SMP under linear stochastic dynamics with exponential quadratic cost function. Explicit solutions are given for both mean-field free and mean-field models.

  17. Strain and Structure Heterogeneity in MoS2 Atomic Layers Grown by Chemical Vapour Deposition

    Science.gov (United States)

    2014-11-18

    cture heterogeneity in MoS2 atomiclayers grown by chemical vapour deposition 6. AUTHORS Zheng Liu, Matin Amani, Sina Najmaei, Quan Xu, Xiaolong Zou...deposition Zheng Liu1•2•3·*, Matin Amani4·*, Sina Najmaei5·*, Quan Xu6•7, Xiaolong Zou5, Wu Zhou8, Ting Yu9, Caiyu Qiu9, A Glen Birdwell4, Frank J. Crowne4

  18. Facile synthesis of new thermally stable and organosoluble ...

    Indian Academy of Sciences (India)

    Hamciuc E, Hamciuc C and Bruma M 2007 Eur. Polym. J. 43 4739. 31. Sponton M, Mercado L A, Ronda J C, Galia M and. Cadiz V 2008 Polym. Degrad. Stabil. 93 2025. 32. Zhang W, Li X, Jiang Y and Yang R 2013 Polym. Degrad. Stabil. 98 246. 33. Ren H, Sun J, Wu B and Zhou Q 2007 Polym. Degrad. Stabil. 92 956. 34.

  19. Genomic Basis of Prostate Cancer Health Disparity Among African-American Men

    Science.gov (United States)

    2013-07-01

    prostatectomy or radiation therapy, the risk of metastasis is reduced, but erectile dysfunction, urinary incontinence , and rectal bleeding may occur...or radiation therapy, the risk of metastasis is reduced, but erectile dysfunction, urinary incontinence and rectal bleeding may occur, affecting the...ProstateCancer/index. 2. Dash A, Lee P, Zhou Q, Jean-Gilles J, Taneja S, Satagopan J, et al. Impact of socioeconomic factors on prostate cancer

  20. Bayesian Computational Sensor Networks for Aircraft Structural Health Monitoring

    Science.gov (United States)

    2016-02-02

    Virginia 22203 Air Force Research Laboratory Air Force Materiel Command 1 Final Performance Report: AFOSR T.C. Henderson , V.J. Mathews, and D...AFRL-AFOSR-VA-TR-2016-0094 Bayesian Computational Sensor Networks for Aircraft Structural Health Monitoring. Thomas Henderson UNIVERSITY OF UTAH SALT...The people who worked on this project include: Thomas C. Henderson , John Mathews, Jingru Zhou, Daimei Zhij, Ahmad Zoubi, Sabita Nahata, Dan Adams

  1. Development of a Vision-Based Robotic Follower Vehicle

    Science.gov (United States)

    2009-02-01

    resultant blob . . . . . . . . . . 14 Figure 13: A sample image and the recognized keypoints found using the SIFT algorithm...Figure 12: An example of a spherical target and the resultant blob (taken from [66]). To track multi-coloured objects, rather than using just one...International Journal of Advanced Robotic Systems, 2(3), 245–250. [37] Zhou, J. and Clark, C. (2006), Autonomous fish tracking by ROV using Monocular

  2. The 2nd International Conference on Water Resource and Environment (WRE 2016

    Directory of Open Access Journals (Sweden)

    Zhouli Liu

    2016-11-01

    Full Text Available Table of contents 01 The eco-toxicological effects of cadmium stress on five ornamental plants Zhouli Liu, Wei Chen, Xingyuan He, Shuai Yu, Weihang Ding 02 Study on the formation and release mechanisms of hydrogen sulfide in Longtan coal mine Jianjun Liu, Yuliang Wu, Kaixiang Fan 03 Coral bleaching in the North Reef of China’s Xisha Islands in 2014 Yuanchao Li, Xinqing Zheng, Shiquan Chen, Haiqun Xie 04 Soil chemical characteristics in a Cunninghamia lanceolata stand suffering from ice-snow damage Jie Li, Zhuomin Wang, Li Xue 05 Diversity of understory vegetation was under a Cunninghamia lanceolata stand suffering from ice-snow damage Zhiyang Lie, Weilong Huang, Tongtong Zhou, Li Xue 06 The effect of water, nitrogen and harvesting time on yield and biomass allocation of Helianthus tuberosus L. Kai Gao, Tiexia Zhu 07 The vertical variation of microbial communities in the sediment of sea cucumber pond Weiteng Mao, Pei Yu, Xinfang Lv, Yunchun Li 08 Indicating significances of alpine plant functional groups to environmental change Peixi Su, Rui Shi 09 Research on the daily CH4 fluxes of soil in summer mangrove community at Yingluogang of Guangxi, China Yong Jiang, Xingbin Chen, Shichu liang 10 Beach protection structures in middle and lower reaches of Yangtze River Junfeng Xu 11 Social responsibility management of large dam project with owner as core: an empirical case in China Jiwei Zhu, Zhao Zhai, Linan Zhou, Yun Le, Li Cao 12 The ecological function value assessment analysis of urban waterfront Jiwei Zhu, Ping Lu, Zhiqian Huang, Bei Zhou 13 Mechanism of diurnal osmotic potential changes and adjustment of three Caragana species in different habitats of the Inner Mongolia Plateau Zhirong Zheng, Shihai Lv, Chaoyang Feng 14 Biodiversity of phytoplankton and environmental influences analysis of Longfeng Wetland, China Nan Song, Yan Liu, Xinxin Lu, Yawen Fan 15 The effect of human activities on culturable soil microbes from Yaoquan Mountain in

  3. Treatment of osteomyelitis defects by a vancomycin-loaded gelatin/β-tricalcium phosphate composite scaffold

    Science.gov (United States)

    Zhou, J.; Zhou, X. G.; Wang, J. W.; Zhou, H.; Dong, J.

    2018-01-01

    Objective In the present study, we aimed to assess whether gelatin/β-tricalcium phosphate (β-TCP) composite porous scaffolds could be used as a local controlled release system for vancomycin. We also investigated the efficiency of the scaffolds in eliminating infections and repairing osteomyelitis defects in rabbits. Methods The gelatin scaffolds containing differing amounts of of β-TCP (0%, 10%, 30% and 50%) were prepared for controlled release of vancomycin and were labelled G-TCP0, G-TCP1, G-TCP3 and G-TCP5, respectively. The Kirby-Bauer method was used to examine the release profile. Chronic osteomyelitis models of rabbits were established. After thorough debridement, the osteomyelitis defects were implanted with the scaffolds. Radiographs and histological examinations were carried out to investigate the efficiency of eliminating infections and repairing bone defects. Results The prepared gelatin/β-TCP scaffolds exhibited a homogeneously interconnected 3D porous structure. The G-TCP0 scaffold exhibited the longest duration of vancomycin release with a release duration of eight weeks. With the increase of β-TCP contents, the release duration of the β-TCP-containing composite scaffolds was decreased. The complete release of vancomycin from the G-TCP5 scaffold was achieved within three weeks. In the treatment of osteomyelitis defects in rabbits, the G-TCP3 scaffold showed the most efficacious performance in eliminating infections and repairing bone defects. Conclusions The composite scaffolds could achieve local therapeutic drug levels over an extended duration. The G-TCP3 scaffold possessed the optimal porosity, interconnection and controlled release performance. Therefore, this scaffold could potentially be used in the treatment of chronic osteomyelitis defects. Cite this article: J. Zhou, X. G. Zhou, J. W. Wang, H. Zhou, J. Dong. Treatment of osteomyelitis defects by a vancomycin-loaded gelatin/β-tricalcium phosphate composite scaffold. Bone Joint Res

  4. International Symposium on Scientific Computing, Computer Arithmetic and Validated Numerics

    CERN Document Server

    DEVELOPMENTS IN RELIABLE COMPUTING

    1999-01-01

    The SCAN conference, the International Symposium on Scientific Com­ puting, Computer Arithmetic and Validated Numerics, takes place bian­ nually under the joint auspices of GAMM (Gesellschaft fiir Angewandte Mathematik und Mechanik) and IMACS (International Association for Mathematics and Computers in Simulation). SCAN-98 attracted more than 100 participants from 21 countries all over the world. During the four days from September 22 to 25, nine highlighted, plenary lectures and over 70 contributed talks were given. These figures indicate a large participation, which was partly caused by the attraction of the organizing country, Hungary, but also the effec­ tive support system have contributed to the success. The conference was substantially supported by the Hungarian Research Fund OTKA, GAMM, the National Technology Development Board OMFB and by the J6zsef Attila University. Due to this funding, it was possible to subsidize the participation of over 20 scientists, mainly from Eastern European countries. I...

  5. Powerful women leaders rise in Asia despite gender inequality.

    Science.gov (United States)

    Over the years, Asia has produced some of the worlds most formidable women leaders, including Indira Ghandi, Madame Mao, Benazir Bhutto, and Corazon Aquino. The list continues with South Asia's leaders, prime ministers, opposition leaders, and vice-presidents, however, such an impressive list does not reflect true equality nor enlightened gender politics. According to Sonny Lo, sociology professor at Hong Kong University, no Asian political system observes true gender equality. It is noted that these Asian leaders rose into prominence after the death or imprisonment of their fathers or husbands. Nevertheless, the elections of Anson Chan and life-long dissident Annette Lu, signal the emergence of a new model for women leaders in Asia. Still, Lo emphasizes that this new trend is merely a reflection of civil service equal opportunity rules. Lo adds that even Taiwan President Chen Sui-Bian's all-women cabinet does not reflect the nation's sentiment, but a wish to project an image.

  6. THE DEMOBILIZATION OF TWO ILLEGAL ARMED GROUPS: ANALYSIS OF THE COVERAGE BY NATIONAL PRESS

    Directory of Open Access Journals (Sweden)

    Yeny Serrano

    2012-12-01

    Full Text Available Given the start of new peace talks between the FARC guerrillas and the Colom-bian government, it is crucial to understand the role of Colombian journalists in reporting peace and war.This article presents an analysis on the National Press coverage of the demobilizations of a paramilitary group (Bloque Cacique Nutibara and a section of the FARC guerrillas (BloqueCacicaGaitana within a frame that reflects over the ethical practice of journalism in the context of war. The results are consistent with literature arguing that ethical codes are not documents dictating how journalists should do their job, but rather they repre-sent political acts of communication which allow journalists to reclaim their prof-fessional independence from sources and defend themselves from threats. The paper also discusses the apparent tension between journalism ethics, and the barriers imposed by the media´s informational needs and the strategic military aims of armed groups.

  7. The 2nd International Conference on Agricultural and Biological Sciences (ABS 2016

    Directory of Open Access Journals (Sweden)

    Lei Pei

    2016-10-01

    Full Text Available Table of contents 01 The influence of soil salt content on the photosynthetic characteristics of spring wheat with trickle irrigation Lei Pei, Zhenhua Wang, Jinzhu Zhang, Wenhao Li 02 Comparing growth of fast-growing and slow-growing endophytes in plants via ergosterol quantification Adeline SY Ting, Yiing Y Chow, Sadequr Rahman 03 Transcriptome and digital gene expression analysis identifies putative triterpene saponin-biosynthetic genes of Panax notoginseng Rongchang Wei 04 Chitosan-assisted isolation and antioxidant evaluation of flavonoids from Sophora japonica L. Zhang Hu, Sidong Li, Chuyan Li, Zijuan Li 05 Two kinds of new characteristics of the ektexine ornamentation of ginkgo pollen Guoxia Wang, Yuzhen Yang, Gang Chen, Qing Luo 06 Analysis of nutrient and medicinal ingredients of Ginkgo pollen in different regions Guoxia Wang, Ruixia Liu, Yuzhen Yang, Lipei Chen 07 Photosynthetic performance of greening seedlings of seven species to drought stress Zhiyang Lie, Tongtong Zhou, Weilong Huang, Li Xue 08 Changes of fluorescence parameters of greening seedlings of seven species under drought stress Jie Li, Zhuomin Wang, Li Xue 09 Mammalian sex hormone affects regeneration capacity and enzymes activity of Triticale L in vitro culture Ismail Bezirganoglu, Pınar Uysal 10 Fractional Fourier entropy increases the recognition rate of fruit type detection Shuihua Wang, Zhihai Lu, Jiquan Yang, Yudong Zhang, John Liu, Ling Wei, Shufang Chen, Preetha Phillips, Zhengchao Dong 11 Banana-peanut intercropping reduces Fusarium wilt disease in banana from enhancing soil bacterial microorganisms and leaf nutrition Hong Li, Xutong Wang, Fengliang Zhao, Guisheng Yang 12 Manganese stress impairs stem ureide nitrogen fixation in yardlong-bean plants in the acidic environment Hong Li 13 A new pest control method for Rhytidodera bowringii Larvae Haijie Huang, Li Zhao, Weijian Huang, Jinhui Wang, Zhongrun Zhang 14 Research on the seed-like Fruits of Subg. Sclarea of

  8. Golden Games

    Institute of Scientific and Technical Information of China (English)

    LI XIAO

    2010-01-01

    @@ China is not expected to sweep the Vancouver 2010 Olympic Winter Games the way it dominated the 2008 Beijing Summer Olympics.However,it has made Chinese Olympic history after winning three gold medals when the Games passed the halfway point of scheduled competition on February 20.On that day,18-year-old Zhou Yang overcame three South Korean rivals to win the women's short-track speed skating 1,500-meter final.

  9. Antimicrobial Peptide-PNA Conjugates Selectively Targeting Bacterial Genes

    Science.gov (United States)

    2013-07-22

    antibacterial therapy. Initial publications suggest that conjugates of cell penetrating peptides and PNA’s can overcome the barrier in transporting ...Zhou, Y., Hou, Z., Meng, J., and Luo, X. Targeting RNA polymerase primary σ70 as a therapeutic strategy against methicillin - resistant ... Staphylococcus aureus by antisense peptide nucleic acid. PLoS One. 2012; 7(1):e29886. 2. Good, L., Sandberg, R., Larsson, O., Nielsen, P.E., and Wahlestedt, C

  10. Distribution of genes associated with yield potential and water ...

    Indian Academy of Sciences (India)

    on the FMs related to yield and water saving in wheat. Till date, six loci ..... Hu Y., Moiwo J. P., Yang Y., Han S. and Yang Y. 2010 Agricul- tural water-saving ... Lyu L., Hu Y., Li Y. and Wang P. 2007 Effect of irrigation treatment on water use ... Zhang Y. J., Fan P. S., Zhang X., Chen C. J. and Zhou M. G. 2009. Quantification of ...

  11. Oligosaccharide nanomedicine of alginate sodium improves therapeutic results of posterior lumbar interbody fusion with cages for degenerative lumbar disease in osteoporosis patients by downregulating serum miR-155

    OpenAIRE

    Qu Y; Wang Z; Zhou H; Kang M; Dong R; Zhao J

    2017-01-01

    Yang Qu, Zhengming Wang, Haohan Zhou, Mingyang Kang, Rongpeng Dong, Jianwu Zhao Department of Orthopedics, The Second Hospital of Jilin University, Changchun, People’s Republic of China Abstract: Degenerative lumbar disease (DLD) is a significant issue for public health. Posterior lumbar intervertebral fusion with cages (PLIFC) has high-level fusion rate and realignment on DLD. However, there are some complications following the surgery. Alginate oligosaccharides (AOS) have antiox...

  12. Mechanisms of carbon, nitrogen and water changes during restoration and succession in tropical and subtropical forest ecosystems

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ With the objective of finding answers to some fundamental problems in ecology and forestry,Prof.ZHOU Guoyi and his colleagues from the CAS South China Botanical Garden set out to clarify whether the oldgrowth forests are actually carbon sinks;how the forest ecosystems,either successional or rehabilitative,react to the nitrogen deposition scenarios and whether there are different reactions working as mechanisms between the mature and immature forest ecosystems.

  13. Phospholipids as Biomarkers for Excessive Alcohol Use

    Science.gov (United States)

    2017-03-01

    17. Zhou P, Ross RA, Pywell CM, Liangpunsakul S, Duffield GE. Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis ...liver disease, alcoholic hepatitis , and alcoholic pancreatitis) among returning veterans at the younger age (~31 years old), compared to previously...Fibrosis in Chronic Hepatitis C Patients: A Systemic Review and Meta- Analysis. J Clin Gastroenterol 2016;50:80-84. 7. Gough G, Heathers L, Puckett D

  14. Review of advanced catheter technologies in radiation oncology brachytherapy procedures

    OpenAIRE

    Zhou J; Zamdborg L; Sebastian E

    2015-01-01

    Jun Zhou,1,2 Leonid Zamdborg,1 Evelyn Sebastian1 1Department of Radiation Oncology, Beaumont Health System, 2Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA Abstract: The development of new catheter and applicator technologies in recent years has significantly improved treatment accuracy, efficiency, and outcomes in brachytherapy. In this paper, we review these advances, focusing on the performance of catheter imaging and reconstruction techniques in brachytherapy ...

  15. International Congress on the History of Oceanography (5th) Held in La Jolla, California on July 7-14, 1993

    Science.gov (United States)

    1994-05-26

    Shang and Zhou Dynasties (21-11 centuries B.C.) fishing gear and marine fishing boats were created and fishing laws initiated. Considerable progress was...secure enactment of fishery reform laws . As the reconstruction effort went forward, the degree to which fisheries effort should be studied...Known as a sensitive reagent since the sixteenth century this test was not regarded as quantitative until Gay- Lussac in 1832 who also introduced a

  16. Sustaining the Knowledge Base of the United States Air Force for Future Operations

    Science.gov (United States)

    2015-12-10

    separates the actual system from the individual. In contrast, Tan , Carrillo, Anumba, Bouchlaghem, Kamara, and Udeaja contended that knowledge management...individual in knowledge management,” 433. 37 Hai Chen Tan et al., “Development of a Methodology for Live Capture and Reuse of Project Knowledge in...Hasan, Maruif and Songkai Nicholas Zhou. “Knowledge Management in Global Organizations,” International Business Research, 8, no. 6 (Spring 2015): 165

  17. Electrospun Fibers for Composites Applications

    Science.gov (United States)

    2014-02-01

    in traditional woven mat composites. Nanofibrous interlayers were used to increase the impact and shear performance of a prepregged carbon fiber...Nylon 66 Nanofibrilmat Interleaved Carbon/Epoxy Laminates . Polymer Composites 2011, 32, 1781–1789. 21 13. Chen, Q.; Zhang, L.; Rahman, A.; Zhou...Resistance in Laminated Composites With Electrospun Nano-Interlayers. Comp. Sci. Tech. 2008, 68, 673– 683. 15. Zhang, J.; Lin, T.; Wang, X. Electrospun

  18. Erratum to 'Surface Modification of PBO Fibers for Composites by Coaxial Atmospheric Dielectric Barrier Discharge (PLA-PLA)'

    International Nuclear Information System (INIS)

    2013-01-01

    There is a mistake in the funding number (National Natural Science Foundation of China (No. 10875146)) of article Surface Modification of PBO Fibers for Composites by Coaxial Atmospheric Dielectric Barrier Discharge (PLA-PLA), written by HU Qianqian, XU Jinzhou, ZHOU Zhenxing, ZHANG Jing, published in Plasma Science and Technology, 2013, Vol. 15, Issue 5, page number 429, it should be corrected as National Natural Science Foundation of China (No. 11075033). (erratum)

  19. Zhou et al., Afr J Tradit Complement Altern Med. (2011) 8(4):405 ‐411

    African Journals Online (AJOL)

    AJTCAM

    from six different habitats in China: Zhejiang Province, Anhui Province, Jiangxi Province, Chongqing City, Hunan Province and Hebei Province. Chemicals and reagents. Analytical grade-methanol was purchased from Sigma Aldrich, UK. HPLC-grade water, acetonitrile and tetrahydrofuran (THF) were purchased from Fisher ...

  20. VizieR Online Data Catalog: Follow-up photometry and spectroscopy of KELT-17 (Zhou+, 2016)

    Science.gov (United States)

    Zhou, G.; Rodriguez, J. E.; Collins, K. A.; Beatty, T.; Oberst, T.; Heintz, T. M.; Stassun, K. G.; Latham, D. W.; Kuhn, R. B.; Bieryla, A.; Lund, M. B.; Labadie-Bartz, J.; Siverd, R. J.; Stevens, D. J.; Gaudi, B. S.; Pepper, J.; Buchhave, L. A.; Eastman, J.; Colon, K.; Cargile, P.; James, D.; Gregorio, J.; Reed, P. A.; Jensen, E. L. N.; Cohen, D. H.; McLeod, K. K.; Tan, T. G.; Zambelli, R.; Bayliss, D.; Bento, J.; Esquerdo, G. A.; Berlind, P.; Calkins, M. L.; Blancato, K.; Manner, M.; Samulski, C.; Stockdale, C.; Nelson, P.; Stephens, D.; Curtis, I.; Kielkopf, J.; Fulton, B. J.; Depoy, D. L.; Marshall, J. L.; Pogge, R.; Gould, A.; Trueblood, M.; Trueblood, P.

    2017-05-01

    KELT-17, the first exoplanet host discovered through the combined observations of both the Kilodegree Extremely Little Telescope (KELT)-North and KELT-South, is located in KELT-South field 06 (KS06) and KELT-North field 14 (KN14), which are both centered on α=07h39m36s δ=+03°00'00'' (J2000). At the time of identification, the post-processed KELT data set included 2092 images from KN14, taken between UT 2011 October 11 and UT 2013 March 26 and 2636 images from KS06 taken between UT 2010 March 02 and 2013 May 10. The discovery light curves from both KELT-North and KELT-South are shown in Figure1. We obtained higher spatial resolution and precision photometric follow-up observations of KELT-17b in multiple filters. An I-band transit was observed on UT 2015 March 05 at the Canela's Robotic Observatory (CROW) with the 0.3m SCT12 telescope, remotely operated from Portalegre, Portugal. Observations were acquired with the ST10XME CCD camera, with a 30'*20' field of view and a 0.86'' pixel scale. A full multi-color (V and I) transit of KELT-17b was observed on UT 2015 March 12 at Kutztown University Observatory (KUO), located on the campus of Kutztown University in Kutztown, Pennsylvania. KUO's main instrument is the 0.6 m Ritchey-Chretien optical telescope with a focal ratio of f/8. The imaging CCD (KAF-6303E) camera has an array of 3K*2K (9μm) pixels and covers a field of view of 19.5'*13.0'. The Peter van de Kamp Observatory (PvdK) at Swarthmore College (near Philadelphia) houses a 0.62m Ritchey-Chretien reflector with a 4K*4K pixel Apogee CCD. The telescope and camera together have a 26'*26' field of view and a 0.61'' pixel scale. PvdK observed KELT-17b on UT 2015 March 12 in the SDSS z' filter. KELT-17b was observed in both g' and i' on UT 2015 March 12 at Wellesley College's Whitin Observatory in Massachusetts. The telescope is a 0.6m Boller and Chivens with a DFM focal reducer yielding an effective focal ratio of f/9.6. We used an Apogee U230 2K*2K camera with a 0.58''/pixel scale and a 20'*20' field of view. One full transit of KELT-17b was observed from the Westminster College Observatory (WCO), PA, on UT 2015 November 4 in the z' filter. The observations employed a 0.35m f/11 Celestron C14 Schmidt-Cassegrain telescope and SBIG STL-6303E CCD with a ~3K*2K array of 9μm pixels, yielding a 24'*16' field of view and 1.4''/pixel image scale at 3*3 pixel binning. The stellar FWHM was seeing-limited with a typical value of ~3.2''. Three full transits of KELT-17b were observed on UT 2016 February 26 (g' and i') and UT 2016 March 31 (r') using the Manner-Vanderbilt Ritchie-Chrtien (MVRC) telescope located at the Mt. Lemmon summit of Steward Observatory, AZ. The observations employed a 0.6m f/8 RC Optical Systems Ritchie-Chretien telescope and SBIG STX-16803 CCD with a 4K*4K array of 9μm pixels, yielding a 26'*26' field of view and 0.39''/pixel image scale. The telescope was heavily defocused for all three observations resulting in a typical stellar FWHM of ~17''. The Perth Exoplanet Survey Telescope (PEST) observatory is a backyard observatory owned and operated by ThiamGuan (TG) Tan, located in Perth, Australia. It is equipped with a 0.3m Meade LX200 SCT f/10 telescope with focal reducer yielding f/5 and an SBIG ST-8XME CCD camera. The telescope and camera combine to have a 31'*21' field of view and a 1.2'' pixel scale. PEST observed KELT-17b on UT 2016 March 06 in the B band. A series of spectroscopic follow-up observations were performed to characterize the KELT-17 system. We performed low-resolution, high-signal-to-noise reconnaissance spectroscopic follow-up of KELT-17 using the Wide Field Spectrograph (WiFeS) on the Australian National University (ANU) 2.3m telescope at Siding Spring Observatory, Australia in 2015 February. In-depth spectroscopic characterization of KELT-17 was performed by the Tillinghast Reflector Echelle Spectrograph (TRES) on the 1.5m telescope at the Fred Lawrence Whipple Observatory, Mount Hopkins, Arizona, USA. TRES has a wavelength coverage of 3900-9100Å over 51 echelle orders, with a resolving power of λ/Δλ R=44000. A total of 12 out-of-transit observations were taken to characterize the radial velocity orbital variations exhibited by KELT-17. In addition, we also observed spectroscopic transits of KELT-17b with TRES on 2016 February 23 and 2016 February 26 UT, gathering 33 and 29 sets of spectra, respectively. (4 data files).

  1. Rational Functions with a General Distribution of Poles on the Real Line Orthogonal with Respect to Varying Exponential Weights: I

    International Nuclear Information System (INIS)

    McLaughlin, K. T.-R.; Vartanian, A. H.; Zhou, X.

    2008-01-01

    Orthogonal rational functions are characterized in terms of a family of matrix Riemann-Hilbert problems on R, and a related family of energy minimisation problems is presented. Existence, uniqueness, and regularity properties of the equilibrium measures which solve the energy minimisation problems are established. These measures are used to derive a family of 'model' matrix Riemann-Hilbert problems which are amenable to asymptotic analysis via the Deift-Zhou non-linear steepest-descent method

  2. Global optima for the Zhou–Rozvany problem

    DEFF Research Database (Denmark)

    Stolpe, Mathias; Bendsøe, Martin P.

    2011-01-01

    We consider the minimum compliance topology design problem with a volume constraint and discrete design variables. In particular, our interest is to provide global optimal designs to a challenging benchmark example proposed by Zhou and Rozvany. Global optimality is achieved by an implementation o...... algorithms, we find global optimal designs for several values on the available volume. These designs can be used to validate other methods and heuristics for the considered class of problems....

  3. China Report, Red Flag, Number 2, 16 January 1985

    Science.gov (United States)

    1985-03-06

    the frustrations we experienced, look at the boom in the film industry and the new situation of unprecedented prosperity since the 3d Plenary...carrying out reforms, and continue to create a new situation in China’s socialist film industry !" At present, reforms are being positively... film industry with Chinese characteristics. This was Comrade Zhou Enlai’s ardent expectation for, faith in, and demand on film artists in his life. We

  4. Mississippi CaP HBCU Undergraduate Research Training Program

    Science.gov (United States)

    2017-11-01

    novel effective treatments and addressing mechanisms of resistance for men with high-risk or metastatic PCa. Likewise, these projects will eventually...Immunoevasion in Prostate Cancer Charles Phillips 2015 TC Senior Biology 3.42 Yin Yuan Mo Long non-coding RNAs as potential diagnostic/prognostic markers in...of 2015) will be coauthors in a manuscript from Drs. Mao and Zhou (mentors). Angel Garcia (Class of 2015) will be coauthor in an article from Dr

  5. Impact of Psychological Needs on Luxury Consumption

    OpenAIRE

    Mao, Ning; McAleer, Michael; Bai, Shuyu

    2017-01-01

    markdownabstractThis paper examines the impact of psychological needs on luxury consumption. Veblen’s Theory of the Leisure Class (1899) invented the term “conspicuous consumption” to describe luxury goods and services, in which Veblen indicated the purpose of luxury consumption was to display wealth and social status. This paper integrates the following two papers: __(1)__ Han and Zhou (2002), who proposed an integrative model, and argued that three variables, namely Country-of-Origin, Brand...

  6. Developing Scene Understanding Neural Software for Realistic Autonomous Outdoor Missions

    Science.gov (United States)

    2017-09-01

    computer using a single graphics processing unit (GPU). To the best of our knowledge, an implementation of the open-source Python -based AlexNet CNN on...1. Introduction Neurons in the brain enable us to understand scenes by assessing the spatial, temporal, and feature relations of objects in the...effort to use computer neural networks to augment human neural intelligence to improve our scene understanding (Krizhevsky et al. 2012; Zhou et al

  7. Relationship of Challenge and Hindrance Stress with Coping Style and Job Satisfaction in Chinese State-Owned Enterprises

    OpenAIRE

    Yamaguchi, Hiroyuki; Zhao, Dong Mei

    2008-01-01

    This study aimed to categorize stresses prevalent in Chinese state-owned enterprises and to investigate the relationships among stresses, coping styles and job satisfaction. Data ( n = 549) were collected from three state-owned enterprises in Cang Zhou, He Bei Province, Mainland China. The result of a factor analysis yielded the following three factors: enterprise stress, interpersonal stress, and challenge stress. In order to test the moderator effect of problem-focused coping and emotion-fo...

  8. Sensitivity of Breast Cancer Stem Cells to TRA-8 Anti-DR5 Monoclonal Antibody

    Science.gov (United States)

    2013-08-01

    Janelia Farm , VA, travel award 2010 -­‐ Translational Medicine Symposium, HHMI Peer Cluster Meeting, travel award 2010 -­‐ AACR Annual Conference...lab. Science Education Alliance, Janelia Farm , VA, 2001 3. Londoño-Joshi AI, Forero-Torres A, Fineberg NS, Oliver PG, Zhou T, LoBuglio AF, Buchsbaum...rabbit mAb and cleaved caspase 3 rabbit mAb were purchased from Cell Signaling (Billerica, MA). Secondary antibodies, Alexa fluor 405 goat anti-rabbit

  9. Cellular neural networks for the stereo matching problem

    International Nuclear Information System (INIS)

    Taraglio, S.; Zanela, A.

    1997-03-01

    The applicability of the Cellular Neural Network (CNN) paradigm to the problem of recovering information on the tridimensional structure of the environment is investigated. The approach proposed is the stereo matching of video images. The starting point of this work is the Zhou-Chellappa neural network implementation for the same problem. The CNN based system we present here yields the same results as the previous approach, but without the many existing drawbacks

  10. IL-6 Receptor Isoforms and Ovarian Cancer Progression

    Science.gov (United States)

    2010-10-01

    carcinoma cell ines, respectively, were obtained from merican Type Culture Collection (Man- ssas, VA). Cells were maintained in Dul- ecco’s Modified...Whether the formation of these ulcers was prompted by prolonged irritation from an open wound, psychological /stress-induced defects in Il62/2 mice...Koyanagi, Y. Zhou, H. Miyamoto, Y. Tanaka, M. Waki, A. Matsumoto , M. Yamamoto, and N. Yamamoto. 1994. Soluble interleukin-6 receptors released from T cell or

  11. Molecular Signatures and Diagnostic Biomarkers of Cumulative, Blast-Graded Mild TBI

    Science.gov (United States)

    2013-10-01

    ischemic stroke. Neurol. Res. 30, 783–793. 35. Wang, H.C., Lin, W.C., Lin, Y.J., Rau, C.S., Lee, T.H., Chang, W.N., Tsai, N.W., Cheng, B.C., Kung , C.T., and...J.K., Shen, C.A., Yin, H.N., Zhou, X.F., Lu, W., Hu, Q.G., Chi, Y.F., Ma, L., 22  Deng, H.P., Zhang, X.B., Sun, T.J., and Han , Y.F. (2010). [Early

  12. RP-HPLCdetermination of ginsenosides RG1 and RB1 in Panax ...

    African Journals Online (AJOL)

    Y Liu, Q He, D Liu, W Wan, X Liu, C Wen, W Fang, W Zhou, Z Xia ... RP-HPLC method is adopted, column used is a ZOBAX SB-C18 column (4.6 mm × 250 mnl, 5 μm), mobile phase A is water, and B is acetonitrile, gradient elution conditions are: 0~20 min (A:B 20:80), 20~60 min (A:B 20~35: 80~65); and detection ...

  13. 天堂的安宁,苏州的和平——苏州的故事:从战争走向和平

    Institute of Scientific and Technical Information of China (English)

    郑茜; 李晓勤

    2004-01-01

    Not long ago,UNESCO's Wolrld Heritage Committee hele its 28th work conference in Suzhou,Ching ,making the beautiful city the focus of attention,In face,even in Ching ,SuZhou is unique,Statistics show only six cities of the more than 140 cities built in the same period as Suzhou survived and only Suzhou has remained in its original place,That is why Chinese historian Gu Jiegang concluded that “Suzhou is Chin's No,1 ancient city.”

  14. Effects of Enhanced Oxygen Delivery by Perfluorocarbons in Spinal Cord Injury

    Science.gov (United States)

    2013-10-01

    indicator of spinal cord ischemia. Acta Med Okayama 1997; 51:71–77. 10. Daugherty WP, Levasseur JE, Sun D, Spiess BD, Bullock MR: Perfluorocarbon... Spiess B. Perflurocarbon emulsions as a promising technology: a review of tissue and vascular gas dynamics. J Appl Physiol 2009; 106: 1444–1452. 12...Neurosurg Spine. 2008; 2: 213-20. 13. Zhou Z, Sun D, Levasseur JE, Merenda A, Hamm RJ, Zhu J, Spiess BD, Bullock MR. Perfluorocarbon emulsions improve

  15. Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review

    OpenAIRE

    Han, Shuwen; Gao, Jianlan; Zhou, Qing; Liu, Shanshan; Wen, Caixia; Yang, Xi

    2018-01-01

    Shuwen Han,1 Jianlan Gao,1 Qing Zhou,2 Shanshan Liu,3 Caixia Wen,3 Xi Yang4 1Department of Medical Oncology, Huzhou Central Hospital, 2Department of Critical Care Medicine, Huzhou Central Hospital, 3Medical College of Nursing, Huzhou University, 4Department of Intervention and Radiotherapy, Huzhou Central Hospital, Huzhou, Zhejiang Province, People’s Republic of China Abstract: Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorec...

  16. Multiscale Mathematics for Nano-Particle-Endowed Active Membranes and Films

    Science.gov (United States)

    2016-08-03

    graduated and move on to either continue their postdoc training or working in universities and industries . The team has been very productive during...6402. 21. Hua Jiang, Hao Yang, Jun Zeng, Zhiyuan Zhou, Jin Peng, Qi Wang, Analytic Oncology, Electron J Metab Nutr Cancer,Jun. 2015,Vol. 2, No. 2, 26...approved for public release. 6 Hill, July 2016-present 2. Norazaliza Mond Gamil, PhD May 2015, Universiti Malaysia Pahang, 2015- present 3. Chen

  17. Regional impairment of intrinsic functional connectivity strength in patients with chronic primary insomnia

    OpenAIRE

    Huang, Suhua; Zhou, Fuqing; Jiang, Jian; Huang, Muhua; Zeng, Xianjun; Ding, Shan; Gong, Honghan

    2017-01-01

    Suhua Huang,1 Fuqing Zhou,2,3 Jian Jiang,2,3 Muhua Huang,2,3 Xianjun Zeng,2,3 Shan Ding,1 Honghan Gong2,3 1Department of Radiology, Jiangxi Province Children’s Hospital, 2Department of Radiology, The First Affiliated Hospital, Nanchang University, 3Jiangxi Province Medical Imaging Research Institute, Nanchang, People’s Republic of China Abstract: Several neuroimaging studies have suggested that brain impairment and plasticity occur in patients with chronic primary insomn...

  18. A Training Program in Breast Cancer Research Using NMR Techniques

    Science.gov (United States)

    2006-07-01

    of Mammographic Masses, IEEE Transactions on Medical Imaging, 2002, vol. 21, No. 2, (Accepted for publication). 9. Mendez AJ, Tahoces PG, Lado MJ...Medical Physics, 2001, Vol. 28, no. 2, pp. 250-258. [7] Mendez AJ, Tahoces PG, Lado MJ, Souto M., Vidal JJ, Computer-aided diagnosis: Automatic...resistant epidermal carcinoma cells Xing-Jie Liang,a Jun-Jie Yin,b Jien-Wei Zhou,c Paul C. Wang,c Barbara Taylor,a Carol Cardarelli,a Michael Kozar,d Raynard

  19. Differential utilization of blood meal amino acids in mosquitoes

    OpenAIRE

    Miesfeld, Roger

    2009-01-01

    Guoli Zhou, Roger MiesfeldDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USAAbstract: Amino acids in the mosquito blood meal have two forms, protein-bound and plasma-free amino acids. To determine if the metabolic fate and flux of these two forms of blood meal amino acids are distinct, we fed mosquitoes eight [14C]-labeled amino acids, seven of which are essential for mosquitoes (leucine, valine, isoleucine, phenylalanine, lysine, arginine, histidine), and one th...

  20. Brief Introduction to Higher Education Institutions in China.

    Science.gov (United States)

    1984-01-12

    51 processor , a 130 computer, a gas chromatograph, a super high speed centrifuge, etc. In addition, there are centralized laboratories such as the...distributed for sale to bookstores internationally and nationally. Technical intel - ligence work has also had a rapid development. The intelligencc re- porting...34, "Nonconductive Polar Leads in Higg’s Dipolar Quark Confinement", etc. All of these essays have been published in the "American Physics Digest" and the "Guang Zhou

  1. Detection of influenza viruses by coupling multiplex reverse-transcription loop-mediated isothermal amplification with cascade invasive reaction using nanoparticles as a sensor

    OpenAIRE

    Ge, Yiyue; Zhou, Qiang; Zhao, Kangchen; Chi, Ying; Liu, Bin; Min, Xiaoyan; Shi, Zhiyang; Zou, Bingjie; Cui, Lunbiao

    2017-01-01

    Yiyue Ge,1 Qiang Zhou,2 Kangchen Zhao,1 Ying Chi,1 Bin Liu,3 Xiaoyan Min,4 Zhiyang Shi,1 Bingjie Zou,2 Lunbiao Cui1 1Institute of Pathogenic Microbiology, Key Laboratories of Enteric Pathogenic Microbiology (Ministry of Health), Jiangsu Provincial Center for Disease Control and Prevention, 2Department of Pharmacology, Jinling Hospital, Medical School of Nanjing University, 3Department of Biomedical Engineering, Nanjing Medical University, 4Department of Geriatrics, The First Affiliated Hospi...

  2. Dependence of Stock Markets with Gold and Bonds under Bullish and Bearish Market States

    OpenAIRE

    Shahzad, Syed Jawad Hussain; Raza, Naveed; Shahbaz, Muhammad; Ali, Azwadi

    2017-01-01

    This paper examines the dependence of gold and benchmark bonds with ten stock markets including five larger developed markets (e.g. USA, UK, Japan, Canada and Germany) and five Eurozone peripheral GIPSI countries (Greece, Ireland, Portuguese, Spain and Ireland) stock markets. We use a novel quantile-on-quantile (QQ) approach to construct the dependence estimates of the quantiles of gold and bond with the quantiles of stock markets. The QQ approach, recently developed by Sim and Zhou (2015), c...

  3. Stalin’s Decision: The Origins of the Korean War

    Science.gov (United States)

    2014-12-01

    gratifying to them [Mao, Zhou, and Huang]…would give me a change to describe American policy…and enable me to carry to Washington most authoritative ... esteem . Stalin was well aware that showing Mao in a positive light would serve two purposes. First, he could play upon Mao’s ego and attempt to gain...Taiwan on hold, Mao directed that the PLA become more self -sufficient and increase agricultural work.264 Furthermore, in order to help alleviate the

  4. Long-term results of a randomized controlled trial evaluating preoperative chemotherapy in resectable non-small cell lung cancer

    OpenAIRE

    Chen, Zhiwei; Luo, Qingquan; Jian, Hong; Zhou, Zhen; Cheng, Baijun; Lu, Shun; Liao, Meilin

    2013-01-01

    Zhiwei Chen,* Qingquan Luo,* Hong Jian, Zhen Zhou, Baijun Cheng, Shun Lu, Meilin LiaoShanghai Lung Tumor Clinical Medical Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China *These authors contributed equallyObjective: We aimed to evaluate whether preoperative chemotherapy provides benefits in the survival and prognosis of patients with non-small cell lung cancer (NSCLC) in resectable stages I to IIIA, except T1N0. Methods: In this ra...

  5. Injection device-related risk management toward safe administration of medications: experience in a university teaching hospital in The People’s Republic of China

    OpenAIRE

    Zhu, Ling-ling; Li, Wei; Song, Ping; Zhou, Quan

    2014-01-01

    Ling-ling Zhu,1 Wei Li,2 Ping Song,3 Quan Zhou3 1Geriatric VIP Ward, Division of Nursing, 2Division of Medical Administration, 3Department of Pharmacy, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of China Abstract: The use of injection devices to administer intravenous or subcutaneous medications is common practice throughout a variety of health care settings. Studies suggest that one-half of all harmful medication errors origi...

  6. Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

    OpenAIRE

    Shay, Jerry W.; Homma, Noriko; Zhou, Ruyun; Naseer, Muhammad Imran; Chaudhary, Adeel G.; Al-Qahtani, Mohammed; Hirokawa, Nobutaka; Goudarzi, Maryam; Fornace, Albert J.; Baeesa, Saleh; Hussain, Deema; Bangash, Mohammed; Alghamdi, Fahad; Schulten, Hans-Juergen; Carracedo, Angel

    2016-01-01

    Table of contents O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabo...

  7. In memoriam Marc Yor séminaire de probabilités XLVII

    CERN Document Server

    Lejay, Antoine; Rouault, Alain

    2015-01-01

    This volume is dedicated to the memory of Marc Yor, who passed away in 2014. The invited contributions by his collaborators and former students bear testament to the value and diversity of his work and of his research focus, which covered broad areas of probability theory. The volume also provides personal recollections about him, and an article on his essential role concerning the Doeblin documents. With contributions by P. Salminen, J-Y. Yen & M. Yor; J. Warren; T. Funaki; J. Pitman& W. Tang; J-F. Le Gall; L. Alili, P. Graczyk & T. Zak; K. Yano & Y. Yano; D. Bakry & O. Zribi; A. Aksamit, T. Choulli & M. Jeanblanc; J. Pitman; J. Obloj, P. Spoida & N. Touzi; P. Biane; J. Najnudel; P. Fitzsimmons, Y. Le Jan & J. Rosen; L.C.G. Rogers & M. Duembgen; E. Azmoodeh, G. Peccati & G. Poly, timP-L Méliot, A. Nikeghbali; P. Baldi; N. Demni, A. Rouault & M. Zani; N. O'Connell; N. Ikeda & H. Matsumoto; A. Comtet & Y. Tourigny; P. Bougerol; L. Chaumont; L. Devroye & ...

  8. Luis Fayad. Dalla narrativa urbana agli innesti socioculturali. Presentazione

    Directory of Open Access Journals (Sweden)

    Martha L. Canfield

    2013-03-01

    Full Text Available The article looks at Luis Fayad’s novel La caída de los puntos cardinales (2000 in order to foreground the influence of Arabic on the Colom- bian author whose grandparents were Lebanese. Born in Bogotá in 1945, Fayad published the novel after being identified as one of the first Colombian novelists dealing with urban literature. It represents a change of direction in his career, as Fayad narrates the entire life of six main characters, four men and two women, who decide to leave Lebanon and migrate to South America, ending up in Colombia. The analysis will focus on the importance of the circulation of the book in Italy by virtue of issues of intercultural exchange embedded in the novel. La caída de los puntos cardinales mixes Arabic tradition and Colombian customs; in the novel, Fayad achieves a cross-cultural story that may provide a successful model of integration. The Spanish-Italian translation and a critical approach to the language used by the novelist and employed by the translator will complete the essay.

  9. Ma Ying-jeou’s Presidential Discourse

    Directory of Open Access Journals (Sweden)

    Jonathan Sullivan

    2012-01-01

    Full Text Available Despite the substantial advances made in cross-Strait relations during Ma Ying-jeou’s (Ma Yingjiu first term, the ROC president’s rhetoric varied considerably as he grappled with the difficult reality of implementing campaign and inauguration pledges to establish better relations with China while striving to maintain national respect and sovereignty. In this article, we put forward a framework for measuring, analysing and explaining this variation in President Ma’s first-term discourse. Analysing a very large number of Ma’s speeches, addresses, etc., we provide empirical assessments of how the content of Ma’s public pronouncements has developed over time, how his rhetoric varies according to the strategic context and timing of a speech, and how his discourse compares to that of his predecessor, Chen Shui-bian (Chen Shuibian. In addressing these questions, the article contributes a quantitative perspective to existing work on political discourse in Taiwan and to the growing methodological and applied literature on how to systematically analyse Chinese political text.

  10. Risk of severe hematologic toxicities in cancer patients treated with PARP inhibitors: results of monotherapy and combination therapy trials

    Directory of Open Access Journals (Sweden)

    Alecu I

    2018-02-01

    Full Text Available Iulian Alecu, Tsveta Milenkova, Simon R Turner Research and Development, AstraZeneca UK Limited, Cambridge, UKThe tolerability profile of PARP inhibitors often includes hematologic toxicities, and the characterization of these adverse events is important to allow effective management by clinicians. Zhou et al1 recently carried out a meta-analysis of the incidence and relative risks of severe neutropenia, thrombocytopenia, and anemia events in 12 randomized controlled trials of PARP inhibitors, either as monotherapy or in combination with chemotherapy or radiotherapy. The authors concluded that olaparib resulted in a higher incidence of severe (common terminology criteria for adverse events [CTCAE] grade $3 neutropenia when compared with niraparib and veliparib; however, these conclusions are based on inappropriate and incomplete comparisons of hematologic toxicity with olaparib or veliparib in combination with myelotoxic chemotherapy versus niraparib monotherapy. While both monotherapy and combination therapy olaparib studies are discussed in the paper, the neutropenia analysis is based on olaparib data solely from studies in combination with paclitaxel or paclitaxel plus carboplatin. In order to inform the practicing clinician of the relative risk of hematologic toxicity associated with different PARP inhibitors, direct comparison needs to be conducted based on monotherapy, where applicable, as per the approved drug indication, otherwise the reader is given misleading information.View the original paper by Zhou et al.

  11. A case of human infection with a novel Babesia species in China.

    Science.gov (United States)

    Man, Su-Qin; Qiao, Ke; Cui, Jie; Feng, Meng; Fu, Yong-Feng; Cheng, Xun-Jia

    2016-03-29

    Babesiosis is an uncommon but emerging tick-borne disease caused by the genus Babesia. In this case study, we report a case of human infection with a novel Babesia sp. in China. The patient in question had been suffering from repetitive occurrences of mild fever of unknown origin and fatigue for 10 years. Ring forms, tetrads, and one or two dots of chromatin or trophozoite-like organisms were observed in the patient's thin blood smears and bone marrow smears. Using a confocal laser-scanning microscope, it was observed that the patient's serum had reactivity with the surface proteins of the B. microti strain. Electron microscopy revealed oval red blood cells with 1 ~ 2 μm of knob protrusions in the cellular membrane. The results of the Babesia-specific nested PCR assay for 18S rRNA confirmed the presence of Babesia infection. The construction of a phylogenetic relationship showed clustering with B. microti and B. duncani, which was identified as a novel Babesia species and named as Babesia sp. XXB/HangZhou. Azithromycin, doxycycline, and moxifloxacin hydrochloride were shown to relieve symptoms but were not as effective after continuous usage. After atovaquone (Mepron®) administration, the patient recovered from fever and tested negative for detection of Babesia-specific genes. Babesia sp. XXB/HangZhou is a novel Babesia species, which causes mild babesiosis in an immunocompetent patient.

  12. Computational-Experimental Processing of Boride/Carbide Composites by Reactive Infusion of Hf Alloy Melts into B4C

    Science.gov (United States)

    2015-09-16

    structure of a packed bed, Semlak-Rhines [18] developed expressions assuming flow through capillary parallel tubes. Martins, Olson and Edwards [19...F. N. Semlak, K.A.Rhines, Trans. Met. Soc. AIME 21, 325 (1958). 19. G. P. Martins, D. L. Olson, and G. R. Edwards , Metall. Trans. B 19, 95 (1988... Snowden , J. Am. Ceram Soc., 72[5], 775 (1989). 29. S. H. Zhou and R. E. Napolitano, Metall. Mater. Trans. A 38, 1145 (2007). 30. J. Viala, J. Bouix

  13. Investigation of Current Situation of Learning Motivation, Social Anxiety and Loneliness of the Left-behind Children in Rural Primary School

    OpenAIRE

    Zhang Biyun; Xu Ming

    2015-01-01

    Objective: To understand the situation of learning motivation, social anxiety and loneliness of the left-behind children. Method: Selecting three rural primary schools in Xian’an District of Xianning City to investigate left-behind situation, learning motivation, social anxiety and loneliness of pupils in Grades 4 to 6 in rural primary school in Xian’an District by the use of the MAAT-I-A which is revised by Zhou Bucheng, the Social Anxiety Scale for Children (SASC) and the Children’s Lonelin...

  14. JPRS Report. Science & Technology: China.

    Science.gov (United States)

    1989-03-17

    MBa2Cu307_y [ Cao Liezhao, et al.; DIWEN WULI XUEBAO, No 4, Dec 88] ... 138 Research on Y-Ba-Cu-0 Superconducting Thin Films at Liquid Nitrogen...Temperatures [Li Yuan, et al.; DIWEN WULI XUEBAO, No 4, Dec 88] 139 Weak-Link Characteristics in High Tc Oxide Superconductivity [ Cao Xiaowen, et al...Xihuai, JOURNAL OF THE CHINESE SILICATE SOCIETY, Vol 1, 1962 p 98. 2. Zhou Yuhua , et al., JOURNAL OF THE CHINESE SILICATE SOCIETY, Vol 4, 1965 p 66

  15. Levels of the Novel Glycoprotein Lacritin in Human Tears After Laser Refractive Surgery

    Science.gov (United States)

    2012-10-01

    be done at the 1 day and 1 week post-operative visit. Each of these tests has been used in clinical practice for years. They are being done for...medical or command authorities. Your name will not appear in any published paper or presentation related to this study. A folder will be maintained...Invest Ophthalmol Vis Sci. 2005;46:863–876. 19. Zhou L, Beuerman RW, Foo Y, Liu S, Ang LP, Tan DT. Character- isation of human tear proteins using high

  16. Prostate Cancer Risk in Relation to IGF-1 and its Genetic Determinants: A Case Control Study Within the Cancer Prostate Sweden Project (CAPS)

    Science.gov (United States)

    2007-05-01

    Endocr Rev 1994;15: 369 –90. 13. Zhou Y, Xu BC, Maheshwari HG, et al. A mammalian model for Laron syndrome produced by targeted disruption of the mouse...hormone–inhibitory syndrome or in GHR knockout animal models, the consequence is markedly lower circulating IGF-I levels (12-14). Therefore, GHR seems...growth hormone receptor/binding protein gene (the Laron mouse). Proc Natl Acad Sci U S A 1997;94:13215–20. 14. Wang Z, Prins GS, Coschigano KT, et al

  17. Exploration of the feasibility for MOOC to be developed for EFL learn-ing in the Chinese Context

    Institute of Scientific and Technical Information of China (English)

    CAO Lian-yang

    2016-01-01

    MOOC is an abbreviation of Massive Open Online Course. Whether MOOC can be developed for EFL learning in the Chinese context is discussed regarding both the advantages and disadvantages. MOOC provides open access to resources of high quality, systematic set of social interactions and assessment, but still needs to enlarge structured EFL learning courses and exam-ine their effectiveness (Wu & Zhou, 2014). The lack of needs analysis and existence of language obstacles are the defects of MOOC for EFL learning in China.

  18. Cyclin D1-AR Crosstalk: Potential Implications for Therapeutic Response in Prostate Cancer

    Science.gov (United States)

    2013-06-01

    metastatic androgen-independent prostate cancer. Clin Cancer Res 2004; 10: 924–928. 12 Toogood PL, Harvey PJ, Repine JT, Sheehan DJ, VanderWel SN, Zhou H et...al. Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6. J Med Chem 2005; 48: 2388–2406. 13 Fry DW, Harvey PJ, Keller PR...cyclin- dependent kinase 6 specific inhibition. J Med Chem 2006; 49: 3826–3831. 58 Lim JT, Mansukhani M, Weinstein IB. Cyclin-dependent kinase 6

  19. A Method to Measure the Amount of Battlefield Situation Information

    Science.gov (United States)

    2014-06-01

    log)( 20 atS  3.2 Measurement of trends information Kierkegaard once said “Life can only be understood backwards, but it must be lived forwards” [8...Towards a theory of s 10 11 , “The Journals of Soren Kierkegaard ”, A selection and translated by Alexander chun, “Formal Description of Command...and 37(2), pp32-64, 1995. [8] Kierkegaard , Soren – Dru , Oxford: Oxford University Press (1938). pp465 [9] ZHOU Dao-an, ZHANG Dong-ge, CHANG Shu

  20. Unraveling the Nature of Chemical Reactivity of Complex Systems

    Science.gov (United States)

    2009-01-13

    28 J. Zhou, J. J. Lin, W. Shiu, and K. Liu, J. Chem. Phys. 119, 4997 2003. 29 S. C. Althorpe, F. Fernandez - Alonso , B. D. Bean, J. D. Ayers, A. E...Truhlar DG, Espinosa- Garcia J (2000) Potential energy surface, thermal, and state-selected rate coefficients, and kinetic isotope effects for Cl CH43...HCl CH3. J Chem Phys 112:9375–9389. 22. Rangel C, Navarrete M, Corchado JC, Espinosa- Garcia J (2006) Potential energy surface, kinetics, and

  1. The Role of Retinal Determination Gene Network (RDGN) in Hormone Signaling Transduction and Prostate Tumorigenes

    Science.gov (United States)

    2015-12-01

    S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG...MP, Wang C, Pestell RG. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget...MP, Quong A, Ertel A, Pestell RG. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74(3):829

  2. A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system

    OpenAIRE

    Wang, Shaowei; Wei, Xiaochun; Sun, Xiaojuan; Chen, Chongwei; Zhou, Jingming; Zhang, Ge; Wu, Heng; Guo, Baosheng; Wei, Lei

    2018-01-01

    Shaowei Wang,1 Xiaochun Wei,1 Xiaojuan Sun,1 Chongwei Chen,1 Jingming Zhou,2 Ge Zhang,3 Heng Wu,3 Baosheng Guo,3 Lei Wei1,2 1Department of Orthopaedics, The 2nd Hospital of Shanxi Medical University, Taiyuan, Shanxi, China; 2Department of Orthopaedics, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA; 3Integrated Traditional Chinese and Western Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Background: C...

  3. Measurement of the Two-photon Absorption Coefficient of Gallium Phosphide (GaP) Using a Dispersion-minimized Sub-10 Femtosecond Z-scan Measurement System

    Science.gov (United States)

    2012-09-01

    Mian et al. (15), if needed. Another source of error occurs when translating the sample in the z-direction that often results in the translation of...4. Li , H. P.; Kam, C. H.; Lam, Y. L.; Zhou, F.; Ji, W. Nonlinear Refraction of Undoped and Fe-doped KTiOAsO4 Crystals in the Femtosecond Regime...Semiconductors with Picosecond Laser Pulses. Phys. Rev. B 1976, 13, 3515. 15. Mian , S. M.; Taheri, B.; Wickstead, J. P. Effects of Beam Ellipticity

  4. A Survey of Cyber Ranges and Testbeds

    Science.gov (United States)

    2013-10-01

    2012. [8] S. W. Neville and K. F. Li , "The Rational for Developing Larger-scale 1000+ Machine Emulation-Based Research Test Beds," WAINA 2009, pp...2002, pp. 6-2671-2676, 6-2678-6- 2682 vol. 6. [20] P. Pederson, D. Lee, G. Shu, D. Chen, Z. Liu, N. Li , and L. Sang, "Virtual Cyber- Security Testing...attacks with applications in homeland defense training." AeroSense 2003. International Society for Optics and Photonics, 2003. [54] Zhou, Mian

  5. A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy

    Science.gov (United States)

    2012-10-01

    target for inhibiting angiogenesis. Expert Opinion on Investigational Drugs 16 (1): 83-107, 2007. 18 21. Veeravagu A, Hsu AR, Cai W, Hou LC, Tse ...inhibition by the particulate form of fullerene derivatives. ACS Nano 2010;4:2773-83. 13. Liu Y, Jiao F, Qiu Y, Li W, Lao F, Zhou G, et al. The effect of...Biochem Pharmacol 2006;71:872-81. 15. Yin JJ, Lao F, Meng J, Fu PP, Zhao Y, Xing G, et al. Inhibition of tumor growth by endohedral metallofullerenol

  6. A non-linear branch and cut method for solving discrete minimum compliance problems to global optimality

    DEFF Research Database (Denmark)

    Stolpe, Mathias; Bendsøe, Martin P.

    2007-01-01

    This paper present some initial results pertaining to a search for globally optimal solutions to a challenging benchmark example proposed by Zhou and Rozvany. This means that we are dealing with global optimization of the classical single load minimum compliance topology design problem with a fixed...... finite element discretization and with discrete design variables. Global optimality is achieved by the implementation of some specially constructed convergent nonlinear branch and cut methods, based on the use of natural relaxations and by applying strengthening constraints (linear valid inequalities...

  7. Enhanced immunization via dissolving microneedle array-based delivery system incorporating subunit vaccine and saponin adjuvant

    OpenAIRE

    Zhao,JiHui; Zhang,Qi-Bo; Liu,Bao; Piao,Xiang-Hua; Yan,Yu-Lu; Hu,Xiao-Ge; Zhou,Kuan; Zhang,Yong-Tai; Feng,Nian-Ping

    2017-01-01

    Ji-Hui Zhao,1,* Qi-Bo Zhang,1,* Bao Liu,2 Xiang-Hua Piao,1 Yu-Lu Yan,1 Xiao-Ge Hu,1 Kuan Zhou,1 Yong-Tai Zhang,1 Nian-Ping Feng1 1School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Anethesiology Department, Augusta University, Augusta, GA, USA *These authors contributed equally to this work Purpose: To enhance the immunogenicity of the model subunit vaccine, ovalbumin (OVA) was combined with platycodin (PD), a ...

  8. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

    Science.gov (United States)

    Turcot, Valérie; Lu, Yingchang; Highland, Heather M; Schurmann, Claudia; Justice, Anne E; Fine, Rebecca S; Bradfield, Jonathan P; Esko, Tõnu; Giri, Ayush; Graff, Mariaelisa; Guo, Xiuqing; Hendricks, Audrey E; Karaderi, Tugce; Lempradl, Adelheid; Locke, Adam E; Mahajan, Anubha; Marouli, Eirini; Sivapalaratnam, Suthesh; Young, Kristin L; Alfred, Tamuno; Feitosa, Mary F; Masca, Nicholas G D; Manning, Alisa K; Medina-Gomez, Carolina; Mudgal, Poorva; Ng, Maggie C Y; Reiner, Alex P; Vedantam, Sailaja; Willems, Sara M; Winkler, Thomas W; Abecasis, Gonçalo; Aben, Katja K; Alam, Dewan S; Alharthi, Sameer E; Allison, Matthew; Amouyel, Philippe; Asselbergs, Folkert W; Auer, Paul L; Balkau, Beverley; Bang, Lia E; Barroso, Inês; Bastarache, Lisa; Benn, Marianne; Bergmann, Sven; Bielak, Lawrence F; Blüher, Matthias; Boehnke, Michael; Boeing, Heiner; Boerwinkle, Eric; Böger, Carsten A; Bork-Jensen, Jette; Bots, Michiel L; Bottinger, Erwin P; Bowden, Donald W; Brandslund, Ivan; Breen, Gerome; Brilliant, Murray H; Broer, Linda; Brumat, Marco; Burt, Amber A; Butterworth, Adam S; Campbell, Peter T; Cappellani, Stefania; Carey, David J; Catamo, Eulalia; Caulfield, Mark J; Chambers, John C; Chasman, Daniel I; Chen, Yii-Der I; Chowdhury, Rajiv; Christensen, Cramer; Chu, Audrey Y; Cocca, Massimiliano; Collins, Francis S; Cook, James P; Corley, Janie; Corominas Galbany, Jordi; Cox, Amanda J; Crosslin, David S; Cuellar-Partida, Gabriel; D'Eustacchio, Angela; Danesh, John; Davies, Gail; Bakker, Paul I W; Groot, Mark C H; Mutsert, Renée; Deary, Ian J; Dedoussis, George; Demerath, Ellen W; Heijer, Martin; Hollander, Anneke I; Ruijter, Hester M; Dennis, Joe G; Denny, Josh C; Di Angelantonio, Emanuele; Drenos, Fotios; Du, Mengmeng; Dubé, Marie-Pierre; Dunning, Alison M; Easton, Douglas F; Edwards, Todd L; Ellinghaus, David; Ellinor, Patrick T; Elliott, Paul; Evangelou, Evangelos; Farmaki, Aliki-Eleni; Farooqi, I Sadaf; Faul, Jessica D; Fauser, Sascha; Feng, Shuang; Ferrannini, Ele; Ferrieres, Jean; Florez, Jose C; Ford, Ian; Fornage, Myriam; Franco, Oscar H; Franke, Andre; Franks, Paul W; Friedrich, Nele; Frikke-Schmidt, Ruth; Galesloot, Tessel E; Gan, Wei; Gandin, Ilaria; Gasparini, Paolo; Gibson, Jane; Giedraitis, Vilmantas; Gjesing, Anette P; Gordon-Larsen, Penny; Gorski, Mathias; Grabe, Hans-Jörgen; Grant, Struan F A; Grarup, Niels; Griffiths, Helen L; Grove, Megan L; Gudnason, Vilmundur; Gustafsson, Stefan; Haessler, Jeff; Hakonarson, Hakon; Hammerschlag, Anke R; Hansen, Torben; Harris, Kathleen Mullan; Harris, Tamara B; Hattersley, Andrew T; Have, Christian T; Hayward, Caroline; He, Liang; Heard-Costa, Nancy L; Heath, Andrew C; Heid, Iris M; Helgeland, Øyvind; Hernesniemi, Jussi; Hewitt, Alex W; Holmen, Oddgeir L; Hovingh, G Kees; Howson, Joanna M M; Hu, Yao; Huang, Paul L; Huffman, Jennifer E; Ikram, M Arfan; Ingelsson, Erik; Jackson, Anne U; Jansson, Jan-Håkan; Jarvik, Gail P; Jensen, Gorm B; Jia, Yucheng; Johansson, Stefan; Jørgensen, Marit E; Jørgensen, Torben; Jukema, J Wouter; Kahali, Bratati; Kahn, René S; Kähönen, Mika; Kamstrup, Pia R; Kanoni, Stavroula; Kaprio, Jaakko; Karaleftheri, Maria; Kardia, Sharon L R; Karpe, Fredrik; Kathiresan, Sekar; Kee, Frank; Kiemeney, Lambertus A; Kim, Eric; Kitajima, Hidetoshi; Komulainen, Pirjo; Kooner, Jaspal S; Kooperberg, Charles; Korhonen, Tellervo; Kovacs, Peter; Kuivaniemi, Helena; Kutalik, Zoltán; Kuulasmaa, Kari; Kuusisto, Johanna; Laakso, Markku; Lakka, Timo A; Lamparter, David; Lange, Ethan M; Lange, Leslie A; Langenberg, Claudia; Larson, Eric B; Lee, Nanette R; Lehtimäki, Terho; Lewis, Cora E; Li, Huaixing; Li, Jin; Li-Gao, Ruifang; Lin, Honghuang; Lin, Keng-Hung; Lin, Li-An; Lin, Xu; Lind, Lars; Lindström, Jaana; Linneberg, Allan; Liu, Ching-Ti; Liu, Dajiang J; Liu, Yongmei; Lo, Ken S; Lophatananon, Artitaya; Lotery, Andrew J; Loukola, Anu; Luan, Jian'an; Lubitz, Steven A; Lyytikäinen, Leo-Pekka; Männistö, Satu; Marenne, Gaëlle; Mazul, Angela L; McCarthy, Mark I; McKean-Cowdin, Roberta; Medland, Sarah E; Meidtner, Karina; Milani, Lili; Mistry, Vanisha; Mitchell, Paul; Mohlke, Karen L; Moilanen, Leena; Moitry, Marie; Montgomery, Grant W; Mook-Kanamori, Dennis O; Moore, Carmel; Mori, Trevor A; Morris, Andrew D; Morris, Andrew P; Müller-Nurasyid, Martina; Munroe, Patricia B; Nalls, Mike A; Narisu, Narisu; Nelson, Christopher P; Neville, Matt; Nielsen, Sune F; Nikus, Kjell; Njølstad, Pål R; Nordestgaard, Børge G; Nyholt, Dale R; O'Connel, Jeffrey R; O'Donoghue, Michelle L; Olde Loohuis, Loes M; Ophoff, Roel A; Owen, Katharine R; Packard, Chris J; Padmanabhan, Sandosh; Palmer, Colin N A; Palmer, Nicholette D; Pasterkamp, Gerard; Patel, Aniruddh P; Pattie, Alison; Pedersen, Oluf; Peissig, Peggy L; Peloso, Gina M; Pennell, Craig E; Perola, Markus; Perry, James A; Perry, John R B; Pers, Tune H; Person, Thomas N; Peters, Annette; Petersen, Eva R B; Peyser, Patricia A; Pirie, Ailith; Polasek, Ozren; Polderman, Tinca J; Puolijoki, Hannu; Raitakari, Olli T; Rasheed, Asif; Rauramaa, Rainer; Reilly, Dermot F; Renström, Frida; Rheinberger, Myriam; Ridker, Paul M; Rioux, John D; Rivas, Manuel A; Roberts, David J; Robertson, Neil R; Robino, Antonietta; Rolandsson, Olov; Rudan, Igor; Ruth, Katherine S; Saleheen, Danish; Salomaa, Veikko; Samani, Nilesh J; Sapkota, Yadav; Sattar, Naveed; Schoen, Robert E; Schreiner, Pamela J; Schulze, Matthias B; Scott, Robert A; Segura-Lepe, Marcelo P; Shah, Svati H; Sheu, Wayne H-H; Sim, Xueling; Slater, Andrew J; Small, Kerrin S; Smith, Albert V; Southam, Lorraine; Spector, Timothy D; Speliotes, Elizabeth K; Starr, John M; Stefansson, Kari; Steinthorsdottir, Valgerdur; Stirrups, Kathleen E; Strauch, Konstantin; Stringham, Heather M; Stumvoll, Michael; Sun, Liang; Surendran, Praveen; Swift, Amy J; Tada, Hayato; Tansey, Katherine E; Tardif, Jean-Claude; Taylor, Kent D; Teumer, Alexander; Thompson, Deborah J; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Thuesen, Betina H; Tönjes, Anke; Tromp, Gerard; Trompet, Stella; Tsafantakis, Emmanouil; Tuomilehto, Jaakko; Tybjaerg-Hansen, Anne; Tyrer, Jonathan P; Uher, Rudolf; Uitterlinden, André G; Uusitupa, Matti; Laan, Sander W; Duijn, Cornelia M; Leeuwen, Nienke; van Setten, Jessica; Vanhala, Mauno; Varbo, Anette; Varga, Tibor V; Varma, Rohit; Velez Edwards, Digna R; Vermeulen, Sita H; Veronesi, Giovanni; Vestergaard, Henrik; Vitart, Veronique; Vogt, Thomas F; Völker, Uwe; Vuckovic, Dragana; Wagenknecht, Lynne E; Walker, Mark; Wallentin, Lars; Wang, Feijie; Wang, Carol A; Wang, Shuai; Wang, Yiqin; Ware, Erin B; Wareham, Nicholas J; Warren, Helen R; Waterworth, Dawn M; Wessel, Jennifer; White, Harvey D; Willer, Cristen J; Wilson, James G; Witte, Daniel R; Wood, Andrew R; Wu, Ying; Yaghootkar, Hanieh; Yao, Jie; Yao, Pang; Yerges-Armstrong, Laura M; Young, Robin; Zeggini, Eleftheria; Zhan, Xiaowei; Zhang, Weihua; Zhao, Jing Hua; Zhao, Wei; Zhao, Wei; Zhou, Wei; Zondervan, Krina T; Rotter, Jerome I; Pospisilik, John A; Rivadeneira, Fernando; Borecki, Ingrid B; Deloukas, Panos; Frayling, Timothy M; Lettre, Guillaume; North, Kari E; Lindgren, Cecilia M; Hirschhorn, Joel N; Loos, Ruth J F

    2018-05-01

    In the version of this article originally published, one of the two authors with the name Wei Zhao was omitted from the author list and the affiliations for both authors were assigned to the single Wei Zhao in the author list. In addition, the ORCID for Wei Zhao (Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) was incorrectly assigned to author Wei Zhou. The errors have been corrected in the HTML and PDF versions of the article.

  9. Coding and signal processing for magnetic recording systems

    CERN Document Server

    Vasic, Bane

    2004-01-01

    RECORDING SYSTEMSA BriefHistory of Magnetic Storage, Dean PalmerPhysics of Longitudinal and Perpendicular Recording, Hong Zhou, Tom Roscamp, Roy Gustafson, Eric Boernern, and Roy ChantrellThe Physics of Optical Recording, William A. Challener and Terry W. McDanielHead Design Techniques for Recording Devices, Robert E. RottmayerCOMMUNICATION AND INFORMATION THEORY OF MAGNETIC RECORDING CHANNELSModeling the Recording Channel, Jaekyun MoonSignal and Noise Generation for Magnetic Recording Channel Simulations, Xueshi Yang and Erozan M. KurtasStatistical Analysis of Digital Signals and Systems, Dra

  10. International Conference on the Application of Accelerators in Research and Industry (11th) Held in Denton, Texas on November 5-8, 1990. Volume 35, Number 8

    Science.gov (United States)

    1991-08-30

    Building, Lyceum. Trilling, Dibitonto, 14:00 EE Atomic Physics and Related Phenomena. Brau, Sulak , Cox, Lockyer. Physics Building, Room 102. Rothard...Oregon. (25 min.) HA 4 "TEXAS": A Calorimeter-Based High.Rate Detector for the SSC. L. SULAK , Boston University. (25 min.) HA 5 A Super Fixed Target...P13’S Zhou, J.- P15l Schneider. D.- 13F5 Sulak , L - IAM Walker, T.G.- BS Ziegler,.- 13A6 Schn..Jcr. i. -:- Sulik, B3.- PAt2 WValter, C.W.- DCS

  11. Preparation of a nano- and micro-fibrous decellularized scaffold seeded with autologous mesenchymal stem cells for inguinal hernia repair

    Directory of Open Access Journals (Sweden)

    Zhang Y

    2017-02-01

    Full Text Available Yinlong Zhang,1,* Yuanyuan Zhou,1,* Xu Zhou,2,* Bin Zhao,1,* Jie Chai,1 Hongyi Liu,1 Yifei Zheng,1 Jinling Wang,3 Yaozong Wang,4 Yilin Zhao2 1Medical College, Xiamen University, 2Department of Oncology and Vascular Intervention Radiology, 3Department of Emergency, 4Department of Orthopaedics, Zhongshan Hospital, Xiamen University, Xiamen, People’s Republic of China *These authors contributed equally to this work Abstract: Prosthetic meshes used for hernioplasty are usually complicated with chronic pain due to avascular fibrotic scar or mesh shrinkage. In this study, we developed a tissue-engineered mesh (TEM by seeding autologous bone marrow-derived mesenchymal stem cells onto nanosized fibers decellularized aorta (DA. DA was achieved by decellularizing the aorta sample sequentially with physical, mechanical, biological enzymatic digestion, and chemical detergent processes. The tertiary structure of DA was constituted with micro-, submicro-, and nanosized fibers, and the original strength of fresh aorta was retained. Inguinal hernia rabbit models were treated with TEMs or acellular meshes (AMs. After implantation, TEM-treated rabbit models showed no hernia recurrence, whereas AM-treated animals displayed bulges in inguinal area. At harvest, TEMs were thicker, have less adhesion, and have stronger mechanical strength compared to AMs (P<0.05. Moreover, TEM showed better cell infiltration, tissue regeneration, and neovascularization (P<0.05. Therefore, these cell-seeded DAs with nanosized fibers have potential for use in inguinal hernioplasty. Keywords: nanobiomaterial, tissue engineering, inguinal hernia, hernioplasty, decellularized aorta 

  12. Eight-dimensional quantum reaction rate calculations for the H+CH4 and H2+CH3 reactions on recent potential energy surfaces.

    Science.gov (United States)

    Zhou, Yong; Zhang, Dong H

    2014-11-21

    Eight-dimensional (8D) transition-state wave packet simulations have been performed on two latest potential energy surfaces (PES), the Zhou-Fu-Wang-Collins-Zhang (ZFWCZ) PES [Y. Zhou, B. Fu, C. Wang, M. A. Collins, and D. H. Zhang, J. Chem. Phys. 134, 064323 (2011)] and the Xu-Chen-Zhang (XCZ)-neural networks (NN) PES [X. Xu, J. Chen, and D. H. Zhang, Chin. J. Chem. Phys. 27, 373 (2014)]. Reaction rate constants for both the H+CH4 reaction and the H2+CH3 reaction are calculated. Simulations of the H+CH4 reaction based on the XCZ-NN PES show that the ZFWCZ PES predicts rate constants with reasonable high accuracy for low temperatures while leads to slightly lower results for high temperatures, in line with the distribution of interpolation error associated with the ZFWCZ PES. The 8D H+CH4 rate constants derived on the ZFWCZ PES compare well with full-dimensional 12D results based on the equivalent m-ZFWCZ PES, with a maximum relative difference of no more than 20%. Additionally, very good agreement is shown by comparing the 8D XCZ-NN rate constants with the 12D results obtained on the ZFWCZ-WM PES, after considering the difference in static barrier height between these two PESs. The reaction rate constants calculated for the H2+CH3 reaction are found to be in good consistency with experimental observations.

  13. Asymmetric correlation of sovereign bond yield dynamics in the Eurozone

    Directory of Open Access Journals (Sweden)

    Dajcman Silvo

    2013-01-01

    Full Text Available This paper examines the symmetry of correlation of sovereign bond yield dynamics between eight Eurozone countries (Austria, Belgium, France, Germany, Ireland, Italy, Portugal, and Spain in the period from January 3, 2000 to August 31, 2011. Asymmetry of correlation is investigated pair-wise by applying the test of Yongmiao Hong, Jun Tu, and Guofu Zhou (2007. Whereas the test of Hong, Tu, and Zhou (2007 is static, the present paper provides also a dynamic version of the test and identifies time periods when the correlation of Eurozone sovereign bond yield dynamics became asymmetric. We identified seven pairs of sovereign bond markets for which the null hypothesis of symmetry in correlation of sovereign bond yield dynamics can be rejected. Calculating rolling-window exceedance correlation, we found that the time-varying upper- (i.e. for positive yield changes and lower-tail correlations (i.e. for negative yield changes for pair-wise observed sovereign bond markets normally follow each other closely, yet during some time periods (for most pair-wise observed countries, these periods are around the September 11 attack on the New York City WTC and around the start of the Greek debt crisis the difference in correlation does increase. The results show that the upper- and lower-tail correlation was symmetric before the Eurozone debt crisis for most of the pair-wise observed sovereign bond markets but has become much less symmetric since then.

  14. Taking a Toll(Toll-free holidays bring massive congestion and opposition by highway operators By Zhou Xiaoyan)

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Dubbed the "'Golden Week," the National Day holiday (normally October 1-7) is a traditional peak travel period for many Chinese who hit the road. But this year's holiday was different from years past: most motorists across the country were exempt from paying toll fees.

  15. The Chinese People’s Liberation Army in 2025

    Science.gov (United States)

    2015-07-01

    George , James Meade , and Antonio Gramsci,” Modern China, No. 37, No. 6, 2011, pp. 646-660. 30. Contrast Zhou Xincheng (周新城), “历史在这里沉思—苏 联解体近  20...the Horizon,” pp. 52-54. 161 54. Ian Anthony, “The ‘Third Tier’ Countries: Production of Major Weapons,” Herbert Wulf, ed., Arms Industry Limited...policies of the George W. Bush admin- istration were very unpopular with regional elites and public opinion, weakening the U.S. position in the Asia

  16. Application of NAA in the sort discrimination of the ancient porcelains

    International Nuclear Information System (INIS)

    Jia Xiuqin; Huang Zhongxiang; Han Song

    2002-01-01

    The neutron activation analysis is applied for analyzing the rare earth elements (REE) and trace elements in the ancient porcelains of Yao Zhou and Ru. The results show that there are differences or even significant differences between glazes and roughcasts of these two ancient porcelains in the gross amounts of REE, normalized diagrams of REE and characteristics of trace element contents, which reflecting the composition differences in glazes and roughcasts of the two kinds of porcelains. Thus, the contents of REE and trace elements can be taken for discriminating the ancient porcelains

  17. Entity information life cycle for big data master data management and information integration

    CERN Document Server

    Talburt, John R

    2015-01-01

    Entity Information Life Cycle for Big Data walks you through the ins and outs of managing entity information so you can successfully achieve master data management (MDM) in the era of big data. This book explains big data's impact on MDM and the critical role of entity information management system (EIMS) in successful MDM. Expert authors Dr. John R. Talburt and Dr. Yinle Zhou provide a thorough background in the principles of managing the entity information life cycle and provide practical tips and techniques for implementing an EIMS, strategies for exploiting distributed processing to hand

  18. Effect of Flake Thickness on Coercivity of Nanocrystalline SmCo5 Bulk Prepared from Anisotropic Nanoflake Powder (Postprint)

    Science.gov (United States)

    2016-08-23

    s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License. [http://dx.doi.org...281, 23 (1998). 5 J. Zhou, R. Skomski, and D. J. Sellmyer, J. Appl . Phys. 93, 6495 (2003). 6 M. Yue, J. H. Zuo, W. Q. Liu, W. C. Lu, D. T. Zhang, J...X. Zhang, Z. H. Guo, and W. Li, J. Appl . Phys. 109, 07A700 (2011). 7 A. M. Gabay, M. Marinescu, J. F. Liu, and G. C. Hadjipanayis, J. Magn. Magn

  19. Fast neutron dosimetry

    International Nuclear Information System (INIS)

    DeLuca, P.M. Jr.; Pearson, D.W.

    1992-01-01

    This progress report concentrates on two major areas of dosimetry research: measurement of fast neutron kerma factors for several elements for monochromatic and white spectrum neutron fields and determination of the response of thermoluminescent phosphors to various ultra-soft X-ray energies and beta-rays. Dr. Zhixin Zhou from the Shanghai Institute of Radiation Medicine, People's Republic of China brought with him special expertise in the fabrication and use of ultra-thin TLD materials. Such materials are not available in the USA. The rather unique properties of these materials were investigated during this grant period

  20. Online Shopping Woes

    Institute of Scientific and Technical Information of China (English)

    Hou Weili

    2011-01-01

    AS a frequent online shopper,Zhou Fangjie,a 28-year-old white-collar worker,was annoyed when she could not open Hanyidushe,an online shop selling Korean-style clothing on Taobao Mall.Her experience resulted from the online protest initiated by small vendors on Taobao Mall,China's largest business to consumer online platform.Thousands of small vendors started the protest against larger established vendors by discrediting them through False orders,forming an anti-Taobao Union and setting up a chat room to devise ways to disrupt operations on Taobao Mall.

  1. X-ray attenuation coefficients and photoelectric cross sections of Cu, Fe and Sn for the energy range 3-29 KeV

    International Nuclear Information System (INIS)

    Wang Dachun; Yang Hua; Luo Pingan; Ding Xunliang; Wang Xinfu; Zhou Hongyu; Shen Xinyin; Zhu Guanghua

    1991-08-01

    The document contains the following two papers: X-ray attenuation coefficient and photoelectric cross sections of Sn for the Energy Range 3.3 KeV to 29.1 KeV - by Wang Dachun, Yang Hua and Luo Pingan. X-ray attenuation coefficients and photoelectric cross sections of Cu and Fe for the range 3 KeV to 29 KeV - by Wang Dachun, Ding Xunliang, Wang Xinfu, Yang Hua, Zhou Hongyu, Shen Xinyin and Zhu Guanghua. A separate abstract was prepared for each of these papers. Refs, figs and tabs

  2. Multi-Functional pi-Conjugated Macromolecules Based on Poly(Phenylene Vinylene)

    Science.gov (United States)

    1994-03-14

    methacrylate-co-4-vinylpyridine)" (in press). 43. J . Polym. Sci., (with R. Vukovic , G. Bogdanic, V. Kuresevic, M. Tomaskovic and W.J. MacKnight) "Phase...Sokolik I Dr. Zhou Yang Dr. Iwao Teraoka IV. JUNIOR RESEARCH PERSONNEL: J . Neill B. Ma. S.L I U i I I i 5 VI. ABSTRACT OF ACCOMPLISHMENTS This report is...chains. I I U I * 14 I VIII. PUBLICATIONS IN PERIOD WITH AFOSR SUPPORT 1. J . Chem. Phys. 98, 712-716 (1993) (with G. Mao, J.E. Fischer and M.J. Winokur

  3. A non-linear branch and cut method for solving discrete minimum compliance problems to global optimality

    DEFF Research Database (Denmark)

    Stolpe, Mathias; Bendsøe, Martin P.

    2007-01-01

    This paper present some initial results pertaining to a search for globally optimal solutions to a challenging benchmark example proposed by Zhou and Rozvany. This means that we are dealing with global optimization of the classical single load minimum compliance topology design problem with a fixed...... finite element discretization and with discrete design variables. Global optimality is achieved by the implementation of some specially constructed convergent nonlinear branch and cut methods, based on the use of natural relaxations and by applying strengthening constraints (linear valid inequalities......) and cuts....

  4. Pondering the Pulvinar.

    Science.gov (United States)

    Lakatos, Peter; O'Connell, Monica N; Barczak, Annamaria

    2016-01-06

    While the function of the pulvinar remains one of the least explored among the thalamic nuclei despite occupying the most thalamic volume in primates, it has long been suspected to play a crucial role in attentive stimulus processing. In this issue of Neuron, Zhou et al. (2016) use simultaneous pulvinar-visual cortex recordings and pulvinar inactivation to provide evidence that the pulvinar is essential for intact stimulus processing, maintenance of neuronal oscillatory dynamics, and mediating the effects of attention. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Some Details from Eurasian Ethnic History – Altaic Peoples, Chinese Sources and Turania

    Directory of Open Access Journals (Sweden)

    Emil Heršak

    2000-12-01

    sources. The list of foreign ethnonyms is large even in the Shang oracles inscriptions. As has been suggested, the Shang distinguished subdued people from hostile outer tribes, indicated by the term fang. Among the peoples noted in the Shang period, most important were the Qiang, Zhou, Quan, Guifang and Yifang. The Qiang and Zhou may have been allied against the Shang, who on their part had special ties with the Quan. The Zhou ultimately led a coalition of peoples against the last Shang ruler precisely at the moment when he was battling in the East against the Yifang. In the following Zhou period, the term fang gradually disappeared and most foreign peoples were to be denoted as Yi (formerly Yifang, Man, Rong and Di. The Zhou also faced a particular threat from the Quanrong (Quan and in the 10th century B.P. deported many of them into outlaying regions – later the Zhou were attacked by a people of unknown origin, the Xianyun, and although the attack was repelled, by the 8th century the Quanrong revived and captured the Zhou capital. This led to the foundation of a new capital in the East, followed by several centuries in which the rulers of various Chinese states assumed a hegemonistic position. It was in this period that the Chinese finally formulated a worldview of themselves as the “Middle Kingdom“, surrounded by “barbarians of the four corners“ – i.e. Yi in the East, Man in the south, Rong in the West and Di in the North. This can be seen as the “first circle“ of foreign peoples around Ancient Chine. Yet when the Chinese state Zhao and later Qin (whose rulers may have originated from the Quanrong expanded to the Ordos and Mongolian border, they reached also a “second circle“ of peoples – in dicated by the ethnonyms Hu, Xiongnu and Yuezhi. Sources at the time also provide often-fantastic references to even further peoples, such as the Dingling in Siberia, who would have constituted a “third circle“ around China. In the final section of the

  6. Dependence of QSAR models on the selection of trial descriptor sets: a demonstration using nanotoxicity endpoints of decorated nanotubes.

    Science.gov (United States)

    Shao, Chi-Yu; Chen, Sing-Zuo; Su, Bo-Han; Tseng, Yufeng J; Esposito, Emilio Xavier; Hopfinger, Anton J

    2013-01-28

    Little attention has been given to the selection of trial descriptor sets when designing a QSAR analysis even though a great number of descriptor classes, and often a greater number of descriptors within a given class, are now available. This paper reports an effort to explore interrelationships between QSAR models and descriptor sets. Zhou and co-workers (Zhou et al., Nano Lett. 2008, 8 (3), 859-865) designed, synthesized, and tested a combinatorial library of 80 surface modified, that is decorated, multi-walled carbon nanotubes for their composite nanotoxicity using six endpoints all based on a common 0 to 100 activity scale. Each of the six endpoints for the 29 most nanotoxic decorated nanotubes were incorporated as the training set for this study. The study reported here includes trial descriptor sets for all possible combinations of MOE, VolSurf, and 4D-fingerprints (FP) descriptor classes, as well as including and excluding explicit spatial contributions from the nanotube. Optimized QSAR models were constructed from these multiple trial descriptor sets. It was found that (a) both the form and quality of the best QSAR models for each of the endpoints are distinct and (b) some endpoints are quite dependent upon 4D-FP descriptors of the entire nanotube-decorator complex. However, other endpoints yielded equally good models only using decorator descriptors with and without the decorator-only 4D-FP descriptors. Lastly, and most importantly, the quality, significance, and interpretation of a QSAR model were found to be critically dependent on the trial descriptor sets used within a given QSAR endpoint study.

  7. Can we still beat "buy-and-hold" for individual stocks?

    Science.gov (United States)

    Hui, Eddie C. M.; Kevin Chan, Ka Kwan

    2014-09-01

    Many investors seek for a trading strategy to beat the "buy-and-hold" strategy. In light of this, Hui and Yam (2014) and Hui et al. (2014) derived a trading strategy from the Shiryaev-Zhou index, and found that the resulting strategy outperformed the "buy-and-hold" strategy for western and Asian securitized real estate indices respectively. However, whether the trading strategy works on individual stocks or not is still unknown. This is the first study to test whether the trading strategy can beat the "buy-and-hold" strategy on individual stocks. We construct two trading strategies and compare the resulting profits with the profits arising from the "buy-and-hold" strategy on Hang Seng Index (HSI), Hang Seng Property (HSP) Index and 12 constituent stocks of HSI during the period December 29, 1995-December 31, 2013. The second strategy (Strategy 2) is a new strategy which incorporates short-selling, and has the effect of multiplying the profit. The results show that our trading strategies are less effective on individual stocks than on stock indices, and are more effective on property stocks than on non-property stocks. Moreover, our strategies outperform "buy-and-hold" by a larger extent on stocks of which the Shiryaev-Zhou indices fluctuate less frequently. Furthermore, by tracking the resulting profits of the three strategies at different times along the whole period of observation, our strategies work better during "bad times" than during "good times". This reflects that our trading strategies are especially useful in protecting investors from substantial loss during market downturns.

  8. Molecular dynamic simulation study of plasma etching L10 FePt media in embedded mask patterning (EMP) process

    OpenAIRE

    Jianxin Zhu; P. Quarterman; Jian-Ping Wang

    2017-01-01

    Plasma etching process of single-crystal L10-FePt media [H. Wang et al., Appl. Phys. Lett. 102(5) (2013)] is studied using molecular dynamic simulation. Embedded-Atom Method [M. S. Daw and M. I. Baskes, Phy. Rev. B 29, 6443 (1984); X. W. Zhou, R. A. Johnson and H. N. G. Wadley, Phy. Rev. B 69, 144113 (2004)] is used to calculate the interatomic potential within atoms in FePt alloy, and ZBL potential [J.F. Ziegler, J. P. Biersack and U. Littmark, “The Stopping and Range of Ions in Matter,” Vol...

  9. Lamb shift of an atom in a dielectric medium

    International Nuclear Information System (INIS)

    Milonni, P.W.; Schaden, M.; Spruch, L.

    1999-01-01

    Adapting an approach used by Feynman for the Lamb shift of an isolated atom, we obtain a nonperturbative expression for the Lamb shift of an atom in a dielectric medium, previously calculated perturbatively [P. W. Milonni, J. Mod. Opt. 42, 1191 (1995)]. The separation of the Lamb and Casimir components of the field energy is greatly simplified, and previous nonperturbative results for the Lamb shift [M. Schaden, L. Spruch, and F. Zhou, Phys. Rev. A 57, 1108 (1998)], based on the generalized argument theorem, are obtained much more easily and directly. copyright 1999 The American Physical Society

  10. The Evolution of Al2O3 Content in Ancient Chinese Glasses

    Directory of Open Access Journals (Sweden)

    Wang Cheng-yu

    2016-01-01

    Full Text Available Based on the evidence from museums, collectors, the dug out of the grave, the evolution of Al2O3 content in Chinese glasses from Western Zhou to Qing dynasty was documented in this paper in detail. It was found that Al2O3 contents in ancient Chinese glasses were relatively higher than those of outside of China in the world. This is the character of the ancient Chinese glasses which is caused by not only the high Al contents in the raw materials but also by the Chinese people’s preference of the milky glasses similar to jade

  11. Multiscale Modeling of Non-crystalline Ceramics (Glass)

    Science.gov (United States)

    2013-03-01

    Aberdeen Proving Ground, MD 2011. 79. Du, Q.; Gunzburger, M. D.; Lehoucq, R. B.; Zhou, K. A nonlocal vector calculus , nonlocal volume-constrained... textbook , ur = − 2µǫ ( J10 − (λ+µ)µ ζJ11 ) π(λ+ 2µ) , uz = 2ǫ ( (λ+µ) λ+2µ ζJ01 + J 0 0 ) π , σz = − 4µǫ (ζJ02 + J 0 1 ) (λ+ µ) πa(λ+ 2µ) , τrz...80). (Throughout, boldface type denotes a vector and a boldface variable with an overbar denotes a tensor.) Equation 31 is a local formulation because

  12. International Conference on Nitride Semiconductors (10th) Held in Washington, DC on August 25-30, 2013

    Science.gov (United States)

    2014-08-17

    Honorary Chair: M. Asif Khan, University of South Carolina, US ’ Program Chair - Russell Dupuis , Georgia Institute of Technology, US - Subject Chair...Russel D. Dupuis 11:00 am-11:15am B4.04 Andrew Armstrong 11:15am-11:30am B4.05 H/lichael Binder 11:30 am-11:46 am B4.06 Marco Ulises...00 pm 87.03 Xiang Zhou 4:00pm-4:15pm B7.04 Christopher J.Lewis 4:15 pm-4:30 pm B7.06 Yamina Andre 4:30 pm-4:45 pm B7.06 Hideaki

  13. Periodic matrix population models: growth rate, basic reproduction number, and entropy.

    Science.gov (United States)

    Bacaër, Nicolas

    2009-10-01

    This article considers three different aspects of periodic matrix population models. First, a formula for the sensitivity analysis of the growth rate lambda is obtained that is simpler than the one obtained by Caswell and Trevisan. Secondly, the formula for the basic reproduction number R0 in a constant environment is generalized to the case of a periodic environment. Some inequalities between lambda and R0 proved by Cushing and Zhou are also generalized to the periodic case. Finally, we add some remarks on Demetrius' notion of evolutionary entropy H and its relationship to the growth rate lambda in the periodic case.

  14. Semantic text relatedness on Al-Qur’an translation using modified path based method

    Science.gov (United States)

    Irwanto, Yudi; Arif Bijaksana, Moch; Adiwijaya

    2018-03-01

    Abdul Baquee Muhammad [1] have built Corpus that contained AlQur’an domain, WordNet and dictionary. He has did initialisation in the development of knowledges about AlQur’an and the knowledges about relatedness between texts in AlQur’an. The Path based measurement method that proposed by Liu, Zhou and Zheng [3] has never been used in the AlQur’an domain. By using AlQur’an translation dataset in this research, the path based measurement method proposed by Liu, Zhou and Zheng [3] will be used to test this method in AlQur’an domain to obtain similarity values and to measure its correlation value. In this study the degree value is proposed to be used in modifying the path based method that proposed in previous research. Degree Value is the number of links that owned by a lcs (lowest common subsumer) node on a taxonomy. The links owned by a node on the taxonomy represent the semantic relationship that a node has in the taxonomy. By using degree value to modify the path-based method that proposed in previous research is expected that the correlation value obtained will increase. After running some experiment by using proposed method, the correlation measurement value can obtain fairly good correlation ties with 200 Word Pairs derive from Noun POS SimLex-999. The correlation value that be obtained is 93.3% which means their bonds are strong and they have very strong correlation. Whereas for the POS other than Noun POS vocabulary that owned by WordNet is incomplete therefore many pairs of words that the value of its similarity is zero so the correlation value is low.

  15. PIXE analysis of proto-porcelain excavated from the Huoshaoshan kiln site in Deqing County, Zhejiang Province

    International Nuclear Information System (INIS)

    Zhang Bin; Cheng Huansheng; Zheng Jianming

    2014-01-01

    Background: Zhejiang Province is an important producing area of proto-porcelain. Huoshaoshan kiln site in Deqing County is the only kiln known currently for firing proto-porcelain from the late Western Zhou Dynasty to the late Spring and Autumn Period. Also it is the earliest kiln site unearthed for only firing proto-porcelain so far. It is of great significance for the exploration of Chinese early celadon firing technology. Purpose: The aim is to disclose the elemental characteristics of these proto-porcelains and study the sources of the raw materials and relationship between these proto-porcelains. Methods: We selected 18 samples made at the early period (from the late Western Zhou Dynasty to the early Spring and Autumn Period), 15 samples made at the middle and last period (the last period of the middle Spring and Autumn Period), and 17 samples made at the last period (the last period of the late Spring and Autumn Period). Proton Induced X-ray Emission (PIXE) was used to analyze these samples and measure the chemical compositions of these proto-porcelains. The factor analysis is used to study the sources of the raw materials and relationship between these proto-porcelains made in the different periods. Results: The results show that for the raw materials of body and glaze, the proto-porcelains at the last period are different from those at the early period, while the same as those at the middle and last period. Conclusion: PIXE combining with factor analysis can be used to study effectively the sources of the raw materials and relationship between these proto-porcelains. (authors)

  16. “六艺”中的“射艺教育”

    Institute of Scientific and Technical Information of China (English)

    李宇

    2015-01-01

    “射艺”是西周时期六艺教育的重要内容。夏商时期“射艺”教育萌芽并初步发展,出现了专门教习射艺的场所及特定专职人员。西周时期国家大事“惟祀与戎”,射艺教育被赋予了新的内容,更加强调了礼乐教化和军事训练的功能,除了礼乐教化的作用外,也在于使贵族阶级的射箭水平有所提高,以备战场上的需要,深层意义上也是为军事的需要而服务的。%ABSTRACT:The “Archery Art” was one of the important contents of the “Six Arts” education in the Western Zhou Dynasty. During the Xia and Shang Dynasties the “Archery Art” emerged and had initial development, and the special grounds for teaching and practicing archery and special archery educational personnel were set. In the Western Zhou Dynasty, “the most important national affairs were nothing but the sacriifce and warfare”, and the archery education was assigned new contents; in addition to the ritual and etiquette functions, the archery education also raised the ifghting abilities of the elite classes to prepare for the battles, therefore its in-depth importance was to meet the military demands.

  17. Next-generation sequence detects ARAP3 as a novel oncogene in papillary thyroid carcinoma

    Directory of Open Access Journals (Sweden)

    Wang QX

    2016-11-01

    Full Text Available Qing-Xuan Wang, En-Dong Chen, Ye-Feng Cai, Yi-Li Zhou, Zhou-Ci Zheng, Ying-Hao Wang, Yi-Xiang Jin, Wen-Xu Jin, Xiao-Hua Zhang, Ou-Chen Wang Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China Purpose: Thyroid cancer is the most frequent malignancies of the endocrine system, and it has became the fastest growing type of cancer worldwide. Much still remains unknown about the molecular mechanisms of thyroid cancer. Studies have found that some certain relationship between ARAP3 and human cancer. However, the role of ARAP3 in thyroid cancer has not been well explained. This study aimed to investigate the role of ARAP3 gene in papillary thyroid carcinoma. Methods: Whole exon sequence and whole genome sequence of primary papillary thyroid carcinoma (PTC samples and matched adjacent normal thyroid tissue samples were performed and then bioinformatics analysis was carried out. PTC cell lines (TPC1, BCPAP, and KTC-1 with transfection of small interfering RNA were used to investigate the functions of ARAP3 gene, including cell proliferation assay, colony formation assay, migration assay, and invasion assay. Results: Using next-generation sequence and bioinformatics analysis, we found ARAP3 genes may play an important role in thyroid cancer. Downregulation of ARAP3 significantly suppressed PTC cell lines (TPC1, BCPAP, and KTC-1, cell proliferation, colony formation, migration, and invasion. Conclusion: This study indicated that ARAP3 genes have important biological implications and may act as a potentially drugable target in PTC. Keywords: papillary thyroid carcinoma, next-generation sequence, ARAP3, oncogene

  18. Evaluation of permanent deformation characteristics of unmodified and Polyethylene Terephthalate modified asphalt mixtures using dynamic creep test

    International Nuclear Information System (INIS)

    Baghaee Moghaddam, Taher; Soltani, Mehrtash; Karim, Mohamed Rehan

    2014-01-01

    Highlights: • Waste PET was utilized as modifier in asphalt mixture. • Deformation characteristics of asphalt mixtures were assessed. • Dynamic creep test was conducted at different temperatures and stress levels. • Permanent deformation models were introduced. - Abstract: One of the major types of plastics that can be found in Municipal Solid Waste (MSW) is Polyethylene Terephthalate (PET) which is a non-biodegradable semi-crystalline thermoplastic polymer, and is considered as polyester material. Generating large amount of waste PET, mainly as bottles, would cause environmental hazards by disposing in landfills. This paper aims to evaluate effects of utilizing waste PET flakes as modifier in asphalt mixture as an alternative solution to overcome the potential risks arise from producing large amount of waste PET as well as evaluating the deformation characteristics of unmodified and PET modified asphalt mixtures. To achieve this aim, different percentages of PET were designated for this investigation, namely: 0%, 0.2%, 0.4%, 0.6%, 0.8% and 1% by weight of aggregate particles, and dynamic creep test was performed at different stress levels (300 kPa and 400 kPa) and temperatures (10 °C, 25 °C and 40 °C). Consequently, Zhou three-stage model was developed. The results showed that permanent deformation characteristics of asphalt mixture were considerably improved by utilization of PET modification, when the permanent strain was remarkably decreased in PET modified mixture compared to the conventional mixture at all stress levels and temperatures. Besides, based on Zhou model, it was concluded that elastic and visco-elastic properties of asphalt mixture were improved by application of PET modification

  19. Estimating chlorophyll content of spartina alterniflora at leaf level using hyper-spectral data

    Science.gov (United States)

    Wang, Jiapeng; Shi, Runhe; Liu, Pudong; Zhang, Chao; Chen, Maosi

    2017-09-01

    Spartina alterniflora, one of most successful invasive species in the world, was firstly introduced to China in 1979 to accelerate sedimentation and land formation via so-called "ecological engineering", and it is now widely distributed in coastal saltmarshes in China. A key question is how to retrieve chlorophyll content to reflect growth status, which has important implication of potential invasiveness. In this work, an estimation model of chlorophyll content of S. alterniflora was developed based on hyper-spectral data in the Dongtan Wetland, Yangtze Estuary, China. The spectral reflectance of S. alterniflora leaves and their corresponding chlorophyll contents were measured, and then the correlation analysis and regression (i.e., linear, logarithmic, quadratic, power and exponential regression) method were established. The spectral reflectance was transformed and the feature parameters (i.e., "san bian", "lv feng" and "hong gu") were extracted to retrieve the chlorophyll content of S. alterniflora . The results showed that these parameters had a large correlation coefficient with chlorophyll content. On the basis of the correlation coefficient, mathematical models were established, and the models of power and exponential based on SDb had the least RMSE and larger R2 , which had a good performance regarding the inversion of chlorophyll content of S. alterniflora.

  20. Single nucleotide polymorphism in the STAT5b gene is associated with body weight and reproductive traits of the Jinghai Yellow chicken.

    Science.gov (United States)

    Zhao, X H; Wang, J Y; Zhang, G X; Wei, Y; Gu, Y P; Yu, Y B

    2012-04-01

    In our research, signal transducer and activator of transcription 5b (STAT5b) gene was studied as candidate gene associated with body weight and reproductive traits of Jinghai Yellow chicken. Single nucleotide polymorphisms (SNPs) of STAT5b gene were examined in both Jinghai Yellow chicken and three reference chicken populations including the Bian, Youxi and Arbor Acre chickens. Two SNPs (C-1591T and G-250A) were detected in the 5' flanking region of STAT5b gene. Association indicated that the C-1591T mutation is significantly associated with age at fist egg, The G-250A mutation is significantly related with hatch weight and body weight at 300 days. Additionally four STAT5b haplotypes (H1, CG; H2, TG; H3, AC and H4, TA) and their frequency distributions were estimated using the phase program. Diplotype H3H4 is dominant for 8, 16 week-age-weight and body weight at first egg. Thus STAT5b gene may be served as a potential genetic marker for growth and reproduction traits evaluation of the Jinghai Yellow chicken. This study will provide valuable information for the protection and breeding of Jinghai Yellow chicken.

  1. [Thoughts and methods of study on acupuncture medical history: an example of Mr. MA Ji-Xing].

    Science.gov (United States)

    Yang, Feng; Zhu, Ling

    2014-03-01

    Mr. MA Ji-xing has devoted himself into the study of acupuncture medical history for more than 70 years. As a result, a great work of Zhenjiuxue Tongshi (see text), History of Acupuncture-Moxibustion) has been completed. The author has expensively studied for history of acupuncture medicine in time and space. Base on abundant historical materials, deliberate textual research as well as strategically situated academic view, it is considered as a masterpiece of acupuncture on real significance. It is worthwhile to note that the book has a systematic and profound explanation on Bian-stone therapy, unearthed literature relics of acupuncture, the bronze figure or illustration of acupoint as well as special topics of Japan and Korea acupuncture history. Filled several gaps of the field, and explored some significant new paths of study, it laid the groundwork for the profound study and unscramble of traditional acupuncture theory as well as the investigation of the academic history, which is considered to have a profound and persistent influence. The careful sorting and profound digging of many distinguish thoughts and methods of Mr. MA Ji-xing in the study of acupuncture medical history has significant meaning in references and enlightenment of the future research on acupuncture medical history.

  2. Large-degree asymptotics of rational Painlevé-II functions: noncritical behaviour

    International Nuclear Information System (INIS)

    Buckingham, Robert J; Miller, Peter D

    2014-01-01

    Rational solutions of the inhomogeneous Painlevé-II equation and of a related coupled Painlevé-II system have recently arisen in studies of fluid vortices and of the sine-Gordon equation. For the sine-Gordon application in particular it is of interest to understand the large-degree asymptotic behaviour of the rational Painlevé-II functions. We explicitly compute the leading-order large-degree asymptotics of these two families of rational functions valid in the whole complex plane with the exception of a neighbourhood of a certain piecewise-smooth closed curve. We obtain rigorous error bounds by using the Deift–Zhou nonlinear steepest-descent method for Riemann–Hilbert problems. (paper)

  3. Spatial data quality and coastal spill modelling

    International Nuclear Information System (INIS)

    Li, Y.; Brimicombe, A.J.; Ralphs, M.P.

    1998-01-01

    Issues of spatial data quality are central to the whole oil spill modelling process. Both model and data quality performance issues should be considered as indispensable parts of a complete oil spill model specification and testing procedure. This paper presents initial results of research that will emphasise to modeler and manager alike the practical issues of spatial data quality for coastal oil spill modelling. It is centred around a case study of Jiao Zhou Bay in the People's Republic of China. The implications for coastal oil spill modelling are discussed and some strategies for managing the effects of spatial data quality in the outputs of oil spill modelling are explored. (author)

  4. Cryptanalysis of the public key encryption based on multiple chaotic systems

    International Nuclear Information System (INIS)

    Zhang Linhua

    2008-01-01

    Recently, Ranjan proposed a novel public key encryption technique based on multiple chaotic systems [Phys Lett 2005;95]. Unfortunately, Wang soon gave a successful attack on its special case based on Parseval's theorem [Wang K, Pei W, Zhou L, et al. Security of public key encryption technique based on multiple chaotic system. Phys Lett A, in press]. In this letter, we give an improved example which can avoid the attack and point out that Wang cannot find the essential drawback of the technique. However, further experimental result shows Ruanjan's encryption technique is inefficient, and detailed theoretic analysis shows that the complexity to break the cryptosystem is overestimated

  5. 教化:荀子伦理思想的本旨%Cultivation(jiaohua,教化):The goal of Xunzi's ethical thought

    Institute of Scientific and Technical Information of China (English)

    詹世友

    2007-01-01

    Xunzi carried on the noble ambitions of"Zhou Kong Jiaohua 周孔教化"and systematically demonstrated the necessity of cultivation and how to realize it.Starting from the belief that human nature is evil,he argues that cultivation was necessary and its teachings must penetrate the mind.The key of cultivation is to cultivate man's feelings,encourage man to behave properly,and attempt to mold his nature through Ritual cultivation,Musical cultivation,and the Five Classics.The main point of Xunzi's ethical thought is cultivation.As far as cultivation theory is concerned,Xunzi's is the most logical and systematic of the famous Pre-Qin thinkers.

  6. A Proteomic Approach to Identify Phosphorylation-Dependent Targets of BRCT Domains

    Science.gov (United States)

    2009-03-01

    Biochemistry, 46, 7706-12 (2007) 77. Dulic, A., P. A. Bates, X. Zhang, S. R. Martin, P. S. Freemont , T. Lindahl & D. E . Barnes: BRCT domain interactions in...5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Zhou Songyang, Ph.D. 5d. PROJECT NUMBER 5e. TASK NUMBER E -Mail: songyang@bcm.tmc.edu 5f. WORK...50 0 50 100 150 200 250 300 0 500 1000 1500 2000 2500 MDC1 with BACH 1 peptide sTime RU R es po ns e .1µM MDC1 .2µM MDC1 .5µM MDC1 1µM MDC1 MDC1-BRCT

  7. "A Personal Reflection on Norodom Sihanouk and Zhou Enlai: An Extraordinary Friendship on the Fringes of the Cold War"

    Directory of Open Access Journals (Sweden)

    Ambassador Julio A. Jeldres

    2012-09-01

    Full Text Available I was sixteen years old when I first read about Norodom Sihanouk and Cambodia. Jacqueline Kennedy’s visit to Cambodia in November 1967 had been widely reported by the press in my homeland, Chile, where her assassinated husband was greatly admired. Through Jackie Kennedy’s visit to Cambodia, I became interested in Norodom Sihanouk’s fascinating life, totally unaware that, years later, our paths would cross and I would become his private secretary. My Cambodian friends often tell me that it was my destiny. In 1967, I wanted to know more about Cambodia. Since there was no information available, I wrote to the Cambodian mission at the United Nations. I found it unbelievable, but four months later I received a handwritten letter back from Sihanouk himself. That began our friendship, which was first conducted through correspondence...

  8. Dynamics for the complex Ginzburg-Landau equation on non-cylindrical domains II: The monotone case

    Science.gov (United States)

    Zhou, Feng; Sun, Chunyou; Cheng, Jiaqi

    2018-02-01

    In this article, we continue the study of the dynamics of the following complex Ginzburg-Landau equation ∂tu - (λ + iα)Δu + (κ + iβ)|u|p-2u - γu = f(t) on non-cylindrical domains. We assume that the spatial domains are bounded and increase with time, which is different from the diffeomorphism case presented in Zhou and Sun [Discrete Contin. Dyn. Syst., Ser. B 21, 3767-3792 (2016)]. We develop a new penalty function to establish the existence and uniqueness of a variational solution satisfying energy equality as well as some energy inequalities and prove the existence of a D -pullback attractor for the non-autonomous dynamical system generated by this class of solutions.

  9. ZHUANGZI((HUANG-TZU)THE SOUNDS OF NATURE

    Institute of Scientific and Technical Information of China (English)

    Cynthia

    2002-01-01

    <正> Life of Zhuangzi Zhuangzi was a Daoist philosopher ofthe pre-Qin era, prior to 221 BC. Accord-ing to the Records of the Historian, his fam-ily name was Zhou and he styled himselfZixiu. He was a native of Meng in the Stateof Song. He lived in poverty all his life andnever acted for his own fame or interest.He was the author of the book Zhuangzi,in which he advocated the same essentialphilosophy as Laozi, in addition to somespecific viewpoints of his own. TheZhuangzi had a deep influence on laterChinese philosophy and literature. According to Daoist scriptures,Zhuangzi was a disciple of ChangsengGongzi and cultivated Dao as a recluse

  10. Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos.

    Science.gov (United States)

    Wang, Xiaochen; Gong, Yuemin; Ema, Hideo

    2016-07-22

    Adult hematopoietic stem cells (HSCs), the ideal system for regenerative research, were isolated at single cell levels decades ago, whereas studies on embryonic HSCs are much more difficult. Zhou et al identified a new pre-HSC cell surface marker, CD201, by which they isolated pre-HSCs at single cell levels for further analyses. The novel expression pattern of HSC development is revealed, including the fundamental role of mammalian targets of rapamycin (mTOR) signaling pathway in HSCs emergence, and the repopulation potential of S/G2/M phase pre-HSCs. Deeper understandings of the cellular origin and developmental regulatory network of HSCs are essential to develop new strategies of generating HSCs in vitro for clinical application.

  11. The present situation of the motivation of learning English in kindergarten——A case on LanZhou in GanSu

    Institute of Scientific and Technical Information of China (English)

    张小花

    2017-01-01

    Motivation is very important in the field of education. This article aims at investigating the present situation of motivation of English learning in kindergarten as well as some feasible suggestions that will be put forward.

  12. Strength of Fibrous Composites

    CERN Document Server

    Huang, Zheng-Ming

    2012-01-01

    "Strength of Fibrous Composites" addresses evaluation of the strength of a fibrous composite by using its constituent material properties and its fiber architecture parameters. Having gone through the book, a reader is able to predict the progressive failure behavior and ultimate strength of a fibrous laminate subjected to an arbitrary load condition in terms of the constituent fiber and matrix properties, as well as fiber geometric parameters. The book is useful to researchers and engineers working on design and analysis for composite materials. Dr. Zheng-Ming Huang is a professor at the School of Aerospace Engineering & Applied Mechanics, Tongji University, China. Mr. Ye-Xin Zhou is a PhD candidate at the Department of Mechanical Engineering, the University of Hong Kong, China.

  13. Restrictive Factors and Output Forecast of Green Development of Agricultural Industry Based on Gray System

    Science.gov (United States)

    Sun, Fengru

    2018-01-01

    This paper analyzes the characteristics of agricultural products from the perspective of agricultural production, farmers’ income, adjustment of agricultural structure and environmental improvement, and analyzes the characteristics of agricultural products in LanZhou area. Through data mining and empirical analysis, the regional agriculture (1) forecasting model of gray system with dynamic data processing, combined with the output data of lily in 2004-2003, the yield prediction is predicted and the fitting state is good and the error is small. Finally, combined with the relevant characteristics of the local characteristics of the agricultural industry to make reference, by changing the characteristics of agricultural production as the center of the mindset, and agricultural industrialization and organic combination, take the characteristics of efficient industrialization of agricultural products.

  14. Fast Shepard interpolation on graphics processing units: potential energy surfaces and dynamics for H + CH4 → H2 + CH3.

    Science.gov (United States)

    Welsch, Ralph; Manthe, Uwe

    2013-04-28

    A strategy for the fast evaluation of Shepard interpolated potential energy surfaces (PESs) utilizing graphics processing units (GPUs) is presented. Speed ups of several orders of magnitude are gained for the title reaction on the ZFWCZ PES [Y. Zhou, B. Fu, C. Wang, M. A. Collins, and D. H. Zhang, J. Chem. Phys. 134, 064323 (2011)]. Thermal rate constants are calculated employing the quantum transition state concept and the multi-layer multi-configurational time-dependent Hartree approach. Results for the ZFWCZ PES are compared to rate constants obtained for other ab initio PESs and problems are discussed. A revised PES is presented. Thermal rate constants obtained for the revised PES indicate that an accurate description of the anharmonicity around the transition state is crucial.

  15. The association between sleep patterns and overweight/obesity in Chinese children: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Zhang B

    2015-08-01

    Full Text Available Bin Zhang,1,* Yanli Hao,2,* Jiangyan Zhou,1,3 Fujun Jia,1 Xueli Li,1 Yi Tang,1 Huirong Zheng1 1Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Mental Health Centre, 2Department of Human Anatomy, Guang Zhou Medical University, 3Department of Psychiatry, Southern Medical University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: This study evaluated the association between sleep patterns and the risk of being overweight/obese in Chinese children. Methods: A total of 3,086 children (1,608 boys and 1,478 girls between 7 and 14 years of age and studying in primary schools were recruited as eligible study participants in this study. We collected the information about children regarding sleep patterns, body height and weight, insomnia, healthy status, time allocation of daily activities, and demographic characteristics using a parental-reported questionnaire. Results: Overweight/obese children were younger, predominantly male, and more prone to have suffered from illness in the past 12 months compared to normal-weight peers. They were also less prone to compensate for sleep deficits during weekends (47.6% vs 39.1%; χ2=11.637, P<0.001 and holidays (52.0% vs 42.0%; χ2=16.057, P<0.001. Sleep duration on weekdays did not affect the risk of being overweight/obese. The adjusted odds ratios for overweight/obesity (noncompensated group using the compensated group as a reference were 1.197 (95% confidence interval [CI]: 1.004–1.493 during weekends and 1.309 (95% CI: 1.052–1.630 during holidays. Conclusion: Compensation for sleep deficits on non-weekdays may ameliorate the risk of being overweight/obese in Chinese children. Moreover, no significant association between the risk of being overweight/obese and sleep duration on weekdays was demonstrated in the current study, which may be due to pervasive sleep insufficiency on weekdays in Chinese children. Keywords: Chinese

  16. A retrospective analysis of the clinicopathological and molecular characteristics of pulmonary blastoma

    Directory of Open Access Journals (Sweden)

    Zhao YY

    2016-11-01

    Full Text Available Yuan-Yuan Zhao,1,* Lin Liu,1,2,* Ting Zhou,1,* Ning-Ning Zhou,1 Yun-Peng Yang,1 Xue Hou,1 Yong Li,3 Hong-Yun Zhao,1 Yan Huang,1 Li Zhang1 1Department of Medical Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 2Department of Medical Oncology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, 3Department of Pathology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People’s Republic of China *These authors contributed equally to this work Purpose: The aim of this study was to analyze and summarize the clinicopathological and molecular characteristics of classic biphasic pulmonary blastoma (PB to improve its diagnosis and treatment. Patients and methods: A retrospective analysis was performed in patients who were diagnosed with PB at Sun Yat-Sen University Cancer Center from March 1995 to March 2015. Genomic DNA was profiled using a capture-based targeted sequencing panel. Results: Sixteen patients with an average age of 40 years were included in this study. Accurate preoperative diagnosis was very challenging as surgically resected tissues with immunohistochemical staining were required for the diagnosis. Surgery was the optimal treatment for localized disease and there was no standard management for metastatic disease. Mutations were detected among 9 out of the 56 genes profiled, including BRCA2, ERBB4, ALK, MET, BRAF, RAF1, PTEN, EGFR, and PIK3CA. Conclusion: Due to the low incidence rate and the reclassification of PB, no standard treatment is available. Although the numbers of cases are few with varying individual experiences, it is important to improve our understanding regarding this rare lung cancer. Targeted DNA sequencing may be of clinical use for molecular testing and the effects of targeted

  17. Butein activates p53 in hepatocellular carcinoma cells via blocking MDM2-mediated ubiquitination

    Directory of Open Access Journals (Sweden)

    Zhou Y

    2018-04-01

    Full Text Available Yuanfeng Zhou,1,2 Kuifeng Wang,2 Ni Zhou,2 Tingting Huang,2 Jiansheng Zhu,2 Jicheng Li1 1Institute of Cell Biology, Zhejiang University, Hangzhou, People’s Republic of China; 2Department of Infectious Diseases, Affiliated Taizhou Hospital of Wenzhou Medical University, Taizhou, People’s Republic of China Introduction: In this study, we aimed to investigate the effect of butein on p53 in hepatocellular carcinoma (HCC cells and the related molecular mechanisms by which p53 was activated. Methods: MTS assay and clonogenic survival assay were used to examine the antitumor activity of butein in vitro. Reporter gene assay was adopted to evaluate p53 transcriptional activity. Flow cytometry and western blotting were performed to study apoptosis induction and protein expression respectively. Xenograft model was applied to determine the in vivo efficacy and the expression of p53 in tumor tissue was detected by immunohistochemistry. Results: HCC cell proliferation and clonogenic survival were significantly inhibited after butein treatment. With the activation of cleaved-PARP and capsase-3, butein induced apoptosis in HCC cells in a dose-dependent manner. The transcriptional activity of p53 was substantially promoted by butein, and the expression of p53-targeted gene was increased accordingly. Mechanism studies demonstrated that the interaction between MDM2 and p53 was blocked by butein and MDM2-mediated p53 ubiquitination was substantially decreased. Short-hairpin RNA experiment results showed that the sensitivity of HCC cells to butein was substantially impaired after p53 was knocked down and butein-induced apoptosis was dramatically decreased. In vivo experiments validated substantial antitumor efficacy of butein against HepG2 xenograft growth, and the expression of p53 in butein-treated tumor tissue was significantly increased. Conclusion: Butein demonstrated potent antitumor activities in HCC by activating p53, and butein or its analogs had

  18. Inverse U-shaped Association between Sleep Duration and Semen Quality: Longitudinal Observational Study (MARHCS) in Chongqing, China

    Science.gov (United States)

    Chen, Qing; Yang, Huan; Zhou, Niya; Sun, Lei; Bao, Huaqiong; Tan, Lu; Chen, Hongqiang; Ling, Xi; Zhang, Guowei; Huang, Linping; Li, Lianbing; Ma, Mingfu; Yang, Hao; Wang, Xiaogang; Zou, Peng; Peng, Kaige; Liu, Taixiu; Cui, Zhihong; Ao, Lin; Roenneberg, Till; Zhou, Ziyuan; Cao, Jia

    2016-01-01

    Study Objectives: To investigate the association between sleep duration and semen parameters as well as reproductive hormone levels. Methods: We designed a cohort of male college students in Chongqing, China. A total of 796 subjects were recruited in 2013 and 656 (82.4%) were followed up in 2014. Each time, semen and peripheral blood samples were collected for semen quality and reproductive hormone measurement. Sleep duration was estimated by revised Munich Chronotype Questionnaire. In 2014, sleep quality was also measured by Pittsburgh Sleep Quality Index (PSQI). Results: There was a substantial inverse U-shaped association between sleep duration and two semen parameters (semen volume and total sperm number), with 7.0–7.5 h/day of sleep showing highest parameters. Either longer or shorter sleep was associated with decreased semen parameters in a dose-response manner (P = 0.002 and 0.001, respectively). Sleeping > 9.0 h was associated with a 21.5% (95% confidence interval 9.2, 32.2) reduction in semen volume and 39.4% (23.3, 52.1) reduction in total sperm number; sleeping ≤ 6.5 h was associated with 4.6% (−10.5, 22.3) and 25.7% (−1.2, 60.1) reduction. Increase of the two parameters was found in those who changed sleep duration toward 7.0–7.5 h/day from 2013 to 2014. The U-shaped association was independent from PSQI and was replicated in another dataset of 1,346 males. No association found between sleep duration and reproductive hormone. Conclusions: Either restricted or excessive sleep may impair semen quality. Further research is needed to validate this finding. Citation: Chen Q, Yang H, Zhou N, Sun L, Bao H, Tan L, Chen H, Ling X, Zhang G, Huang L, Li L, Ma M, Yang H, Wang X, Zou P, Peng K, Liu T, Cui Z, Ao L, Roenneberg T, Zhou Z, Cao J. Inverse u-shaped association between sleep duration and semen quality: longitudinal observational study (MARHCS) in Chongqing, China. SLEEP 2016;39(1):79–86. PMID:26350472

  19. Sensory quality evaluation for appearance of needle-shaped green tea based on computer vision and nonlinear tools.

    Science.gov (United States)

    Dong, Chun-Wang; Zhu, Hong-Kai; Zhao, Jie-Wen; Jiang, Yong-Wen; Yuan, Hai-Bo; Chen, Quan-Sheng

    2017-06-01

    Tea is one of the three greatest beverages in the world. In China, green tea has the largest consumption, and needle-shaped green tea, such as Maofeng tea and Sparrow Tongue tea, accounts for more than 40% of green tea (Zhu et al., 2017). The appearance of green tea is one of the important indexes during the evaluation of green tea quality. Especially in market transactions, the price of tea is usually determined by its appearance (Zhou et al., 2012). Human sensory evaluation is usually conducted by experts, and is also easily affected by various factors such as light, experience, psychological and visual factors. In the meantime, people may distinguish the slight differences between similar colors or textures, but the specific levels of the tea are hard to determine (Chen et al., 2008). As human description of color and texture is qualitative, it is hard to evaluate the sensory quality accurately, in a standard manner, and objectively. Color is an important visual property of a computer image (Xie et al., 2014; Khulal et al., 2016); texture is a visual performance of image grayscale and color changing with spatial positions, which can be used to describe the roughness and directivity of the surface of an object (Sanaeifar et al., 2016). There are already researchers who have used computer visual image technologies to identify the varieties, levels, and origins of tea (Chen et al., 2008; Xie et al., 2014; Zhu et al., 2017). Most of their research targets are crush, tear, and curl (CTC) red (green) broken tea, curly green tea (Bilochun tea), and flat-typed green tea (West Lake Dragon-well green tea) as the information sources. However, the target of the above research is to establish a qualitative evaluation method on tea quality (Fu et al., 2013). There is little literature on the sensory evaluation of the appearance quality of needle-shaped green tea, especially research on a quantitative evaluation model (Zhou et al., 2012; Zhu et al., 2017).

  20. Charge-signal multiplication mediated by urea wires inside Y-shaped carbon nanotubes

    International Nuclear Information System (INIS)

    Lv, Mei; Liu, Zengrong; He, Bing; Xiu, Peng; Tu, Yusong

    2014-01-01

    In previous studies, we reported molecular dynamics (MD) simulations showing that single-file water wires confined inside Y-shaped single-walled carbon nanotubes (Y-SWNTs) held strong and robust capability to convert and multiply charge signals [Y. S. Tu, P. Xiu, R. Z. Wan, J. Hu, R. H. Zhou, and H. P. Fang, Proc. Natl. Acad. Sci. U.S.A. 106, 18120 (2009); Y. Tu, H. Lu, Y. Zhang, T. Huynh, and R. Zhou, J. Chem. Phys. 138, 015104 (2013)]. It is fascinating to see whether the signal multiplication can be realized by other kinds of polar molecules with larger dipole moments (which make the experimental realization easier). In this article, we use MD simulations to study the urea-mediated signal conversion and multiplication with Y-SWNTs. We observe that when a Y-SWNT with an external charge of magnitude 1.0 e (the model of a signal at the single-electron level) is solvated in 1 M urea solutions, urea can induce drying of the Y-SWNT and fill its interiors in single-file, forming Y-shaped urea wires. The external charge can effectively control the dipole orientation of the urea wire inside the main channel (i.e., the signal can be readily converted), and this signal can further be multiplied into 2 (or more) output signals by modulating dipole orientations of urea wires in bifurcated branch channels of the Y-SWNT. This remarkable signal transduction capability arises from the strong dipole-induced ordering of urea wires under extreme confinement. We also discuss the advantage of urea as compared with water in the signal multiplication, as well as the robustness and biological implications of our findings. This study provides the possibility for multiplying signals by using urea molecules (or other polar organic molecules) with Y-shaped nanochannels and might also help understand the mechanism behind signal conduction in both physical and biological systems

  1. Recombinant human parvovirus B19 vectors: erythroid cell-specific delivery and expression of transduced genes.

    Science.gov (United States)

    Ponnazhagan, S; Weigel, K A; Raikwar, S P; Mukherjee, P; Yoder, M C; Srivastava, A

    1998-06-01

    A novel packaging strategy combining the salient features of two human parvoviruses, namely the pathogenic parvovirus B19 and the nonpathogenic adeno-associated virus type 2 (AAV), was developed to achieve erythroid cell-specific delivery as well as expression of the transduced gene. The development of such a chimeric vector system was accomplished by packaging heterologous DNA sequences cloned within the inverted terminal repeats of AAV and subsequently packaging the DNA inside the capsid structure of B19 virus. Recombinant B19 virus particles were assembled, as evidenced by electron microscopy as well as DNA slot blot analyses. The hybrid vector failed to transduce nonerythroid human cells, such as 293 cells, as expected. However, MB-02 cells, a human megakaryocytic leukemia cell line which can be infected by B19 virus following erythroid differentiation with erythropoietin (N. C. Munshi, S. Z. Zhou, M. J. Woody, D. A. Morgan, and A. Srivastava, J. Virol. 67:562-566, 1993) but lacks the putative receptor for AAV (S. Ponnazhagan, X.-S. Wang, M. J. Woody, F. Luo, L. Y. Kang, M. L. Nallari, N. C. Munshi, S. Z. Zhou, and A. Srivastava, J. Gen. Virol. 77:1111-1122, 1996), were readily transduced by this vector. The hybrid vector was also found to specifically target the erythroid population in primary human bone marrow cells as well as more immature hematopoietic progenitor cells following erythroid differentiation, as evidenced by selective expression of the transduced gene in these target cells. Preincubation with anticapsid antibodies against B19 virus, but not anticapsid antibodies against AAV, inhibited transduction of primary human erythroid cells. The efficiency of transduction of primary human erythroid cells by the recombinant B19 virus vector was significantly higher than that by the recombinant AAV vector. Further development of the AAV-B19 virus hybrid vector system should prove beneficial in gene therapy protocols aimed at the correction of inherited and

  2. Recombinant Human Parvovirus B19 Vectors: Erythroid Cell-Specific Delivery and Expression of Transduced Genes

    Science.gov (United States)

    Ponnazhagan, Selvarangan; Weigel, Kirsten A.; Raikwar, Sudhanshu P.; Mukherjee, Pinku; Yoder, Mervin C.; Srivastava, Arun

    1998-01-01

    A novel packaging strategy combining the salient features of two human parvoviruses, namely the pathogenic parvovirus B19 and the nonpathogenic adeno-associated virus type 2 (AAV), was developed to achieve erythroid cell-specific delivery as well as expression of the transduced gene. The development of such a chimeric vector system was accomplished by packaging heterologous DNA sequences cloned within the inverted terminal repeats of AAV and subsequently packaging the DNA inside the capsid structure of B19 virus. Recombinant B19 virus particles were assembled, as evidenced by electron microscopy as well as DNA slot blot analyses. The hybrid vector failed to transduce nonerythroid human cells, such as 293 cells, as expected. However, MB-02 cells, a human megakaryocytic leukemia cell line which can be infected by B19 virus following erythroid differentiation with erythropoietin (N. C. Munshi, S. Z. Zhou, M. J. Woody, D. A. Morgan, and A. Srivastava, J. Virol. 67:562–566, 1993) but lacks the putative receptor for AAV (S. Ponnazhagan, X.-S. Wang, M. J. Woody, F. Luo, L. Y. Kang, M. L. Nallari, N. C. Munshi, S. Z. Zhou, and A. Srivastava, J. Gen. Virol. 77:1111–1122, 1996), were readily transduced by this vector. The hybrid vector was also found to specifically target the erythroid population in primary human bone marrow cells as well as more immature hematopoietic progenitor cells following erythroid differentiation, as evidenced by selective expression of the transduced gene in these target cells. Preincubation with anticapsid antibodies against B19 virus, but not anticapsid antibodies against AAV, inhibited transduction of primary human erythroid cells. The efficiency of transduction of primary human erythroid cells by the recombinant B19 virus vector was significantly higher than that by the recombinant AAV vector. Further development of the AAV-B19 virus hybrid vector system should prove beneficial in gene therapy protocols aimed at the correction of inherited

  3. Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency

    Directory of Open Access Journals (Sweden)

    Bian X

    2016-05-01

    Full Text Available Xinyu Bian,* Puyuan Wu,* Huizi Sha, Hanqing Qian, Qing Wang, Lei Cheng, Yang Yang, Mi Yang, Baorui LiuComprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workAbstract: In this study, we report a novel kind of targeting with paclitaxel (PTX-loaded silk fibroin nanoparticles conjugated with iRGD–EGFR nanobody recombinant protein (anti-EGFR-iRGD. The new nanoparticles (called A-PTX-SF-NPs were prepared using the carbodiimide-mediated coupling procedure and their characteristics were evaluated. The cellular cytotoxicity and cellular uptake of A-PTX-SF-NPs were also investigated. The results in vivo suggested that NPs conjugated with the recombinant protein exhibited more targeting and anti-neoplastic property in cells with high EGFR expression. In the in vivo antitumor efficacy assay, the A-PTX-SF-NPs group showed slower tumor growth and smaller tumor volumes than PTX-SF-NPs in a HeLa xenograft mouse model. A real-time near-infrared fluorescence imaging study showed that A-PTX-SF-NPs could target the tumor more effectively. These results suggest that the anticancer activity and tumor targeting of A-PTX-SF-NPs were superior to those of PTX-SF-NPs and may have the potential to be used for targeted delivery for tumor therapies. Keywords: EGFR, nanobody, iRGD, recombinant protein, targeting drug carriers, antitumor efficiency

  4. El Negocio Renta ble del Siglo XXI: La Trata de Personas, el caso de los esclavos colombianos resca tados en Argentina en 2013 - The Profitable Business of XXI Century: Human Trafficking, the case of Colombian slaves rescued in Argentinain 2013

    Directory of Open Access Journals (Sweden)

    TORRES ARTEAGA, Lyda María

    2014-06-01

    Full Text Available It’s amazing being in the XXI century keep talking about phenomena such as slavery, which has pushed the boundaries of time and for generations has kept among us, in relation to new modern slavery cases of Bolivia and Brazil are widely acknowledged, without But today manifest more strongly sensitize us different facts on the issue and shows us even closer than we had imagined. Precisely in 2013 were able to rescue a group of about 200 Colombians were subjected under a network trafficking that led to Argentina to be exploited at work , a situation that calls us to be more vigilant against the new form of slavery given today through deception and bids to improve the standard of living . The network of Colom- bians kept under slave labor more than 200 nationals, was made up of 23 people, who were responsible for making contact with victims and move them to Argentina under the delusion that they would work in the form of cooperative once arrived in the country had no chance of return. It should be mentioned that in recent years, trafficking for labor and sexual exploitation has been placed on the political and social agenda, thanks to the media exposure they acquired different cases around the world, which has led it to be a topic of wide interest and joint work between civil society, state and international agencies and / or foundations of the same charge .

  5. S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis.

    Science.gov (United States)

    Fang, Chao; Bian, Ganlan; Ren, Pan; Xiang, Jie; Song, Jun; Yu, Caiyong; Zhang, Qian; Liu, Ling; Chen, Kun; Liu, Fangfang; Zhang, Kun; Wu, Chunfeng; Sun, Ruixia; Hu, Dan; Ju, Gong; Wang, Jian

    2018-02-08

    Spinster homolog 2 (SPNS2) is the membrane transporter of sphingosine-1-phosphate (S1P), and it participates in several physiologic processes by activating different S1P receptors (S1PRs). However, its functions in the nervous system remain largely unclear. We explored the important role of SPNS2 in the process of retinal morphogenesis using a spns2-deficient rat model. In the absence of the functional SPNS2 transporter, we observed progressively aggravating laminar disorganization of the epithelium at the postnatal stage of retinal development. Disrupted cell polarity, delayed cell-cycle exit of retinal progenitor cells, and insufficient migration of newborn neurons were proposed in this study as potential mechanisms accounting for this structural disorder. In addition, we analyzed the expression profiles of spns2 and s1prs, and proposed that SPNS2 regulated retinal morphogenesis by establishing the S1P level in the eye and activating S1PR3 signaling. These data indicate that SPNS2 is indispensable for normal retinal morphogenesis and provide new insights on the role of S1P in the developing retina using an established in vivo model.-Fang, C., Bian, G., Ren, P., Xiang, J., Song, J., Yu, C., Zhang, Q., Liu, L., Chen, K., Liu, F., Zhang, K., Wu, C., Sun, R., Hu, D., Ju, G., Wang, J. S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis.

  6. The Boju Tripod

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    In 1975, archaeologists discovered a graveyard of imperial kinsmen as well as the ruins of the ancient State of Yan around Dongjialin Village by the Liuli River in Fangshan County to the southwest of Beijing. A large number of bronze vessels made for sacrificial rites were excavated. According to their inscriptions, historians believe that the State of Yan existed from about 11 B.C. to 771 B.C. and that the first fiefdoms of the State of Yan were located at the site of the ruins. Out of all these bronze vessels, the Boju Tripod is distinctive with its unique shape. This tripod dates back to the early years of the Western Zhou Dynasty. It is 33 cm tall, with a bore of 22.9 cm. The lid is

  7. Two-point resistance of a resistor network embedded on a globe.

    Science.gov (United States)

    Tan, Zhi-Zhong; Essam, J W; Wu, F Y

    2014-07-01

    We consider the problem of two-point resistance in an (m-1) × n resistor network embedded on a globe, a geometry topologically equivalent to an m × n cobweb with its boundary collapsed into one single point. We deduce a concise formula for the resistance between any two nodes on the globe using a method of direct summation pioneered by one of us [Z.-Z. Tan, L. Zhou, and J. H. Yang, J. Phys. A: Math. Theor. 46, 195202 (2013)]. This method is contrasted with the Laplacian matrix approach formulated also by one of us [F. Y. Wu, J. Phys. A: Math. Gen. 37, 6653 (2004)], which is difficult to apply to the geometry of a globe. Our analysis gives the result in the form of a single summation.

  8. Component Commonality and Its Cost Implications - Increasing the Commonality of the Right Components

    DEFF Research Database (Denmark)

    Lyly-Yrjänäinen, Jouni; Suomala, Petri; Israelsen, Poul

    Component commonality (Labro 2004, Zhou & Gruppström 2004) can be defined as the use of the same version of a component across multiple products. It is usually seen as a means to manage costs without sacrificing product variety. However, when managing costs with component commonality, the managers...... constructions was identified as the most important bottleneck for the delivery process causing many indirect costs, especially with respect to project-management-related activities. Interestingly, by eliminating the need for mechanical engineering, the context starts to approach assembly-to-order context, also...... should be able to identify rather rapidly which group of components would enable the most significant cost reductions. Unfortunately, the existing literature lacks profound discussion of how to identify the right components for increased component commonality. The objective of the paper is to discuss how...

  9. An experimental and numerical investigation of crossflow effects in two-phase displacements

    DEFF Research Database (Denmark)

    Cinar, Y.; Jessen, Kristian; Berenblyum, Roman

    2006-01-01

    In this paper, we present flow visualization experiments and numerical simulations that demonstrate the combined effects of viscous and capillary forces and gravity segregation on crossflow that occurs in two-phase displacements in layered porous media. We report results of a series of immiscible...... flooding experiments in 2D, two-layered glass bead models. Favorable mobility-ratio imbibition and unfavorable mobility-ratio drainage experiments were performed. We used pre-equilibrated immiscible phases from a ternary isooctane/isopropanol/water system, which allowed control of the interfacial tension....... The experiments also illustrate the complex interplay of capillary, gravity, and viscous forces that controls crossflow. The experimental results confirm that the transition ranges of scaling groups suggested by Zhou et al. (1994) are appropriate/valid. We report also results of simulations of the displacement...

  10. Photodissociation of Small Molecules and Photoionization of Free Radicals Using the VUV Velocity-Map Imaging Photoion and Photoelectron Method

    Science.gov (United States)

    Gao, Hong

    The tunable vacuum ultraviolet (VUV) laser generated through the two-photon resonance-enhanced four-wave mixing scheme is combined with the newly developed time-slice velocity map imaging photoion method to study the photodissociation of small molecules in the VUV region, and with the velocity map imaging photoelectron method to study the photoionization of free radicals. The photodissociation dynamics of NO in the energy region around 13.5 eV has been investigated. Branching ratios of the three lowest dissociation channels of 12C 16O that produce C(3P) + O(3P), C( 1D) + O(3P) and C(3P) + O(1D) are measured for the first time in the VUV region from 102,500 cm-1 to 110,500 cm-1, valuable information of the dissociation dynamics for this prototype system has been deduced. We demonstrated an experiment that has two independently tunable VUV lasers and a time-slice velocity map imaging setup, this provides us a global way to perform systematic state-selected photodissociation of small molecules via state-selected detection of the atomic products in the VUV region. The velocity map imaging photoelectron method was successfully used to obtain the photoelectron spectrum of the propargyl radical (C3H3) via a single VUV photoionization process. The propargyl radical is generated by the 193 nm laser photodissociation of the precursor C3H3Cl. This is the first time that the velocity map imaging photoelectron method is used to get the photoelectron spectra of free radicals, indicating that it is a powerful technique for studying the photoionization of free radicals which are always hard to be produced with high enough number densities for spectroscopic studies. This dissertation is mainly based on the following peer-reviewed journal articles: 1. Hong Gao, Yang Pan, Lei Yang, Jingang Zhou, C. Y. Ng and William M. Jackson. "Time-slice velocity-map ion imaging studies of the Photodissociation of NO in the vacuum ultraviolet region", the Journal of Chemical Physics, 136, 134302

  11. A big data geospatial analytics platform - Physical Analytics Integrated Repository and Services (PAIRS)

    Science.gov (United States)

    Hamann, H.; Jimenez Marianno, F.; Klein, L.; Albrecht, C.; Freitag, M.; Hinds, N.; Lu, S.

    2015-12-01

    A big data geospatial analytics platform:Physical Analytics Information Repository and Services (PAIRS)Fernando Marianno, Levente Klein, Siyuan Lu, Conrad Albrecht, Marcus Freitag, Nigel Hinds, Hendrik HamannIBM TJ Watson Research Center, Yorktown Heights, NY 10598A major challenge in leveraging big geospatial data sets is the ability to quickly integrate multiple data sources into physical and statistical models and be run these models in real time. A geospatial data platform called Physical Analytics Information and Services (PAIRS) is developed on top of open source hardware and software stack to manage Terabyte of data. A new data interpolation and re gridding is implemented where any geospatial data layers can be associated with a set of global grid where the grid resolutions is doubling for consecutive layers. Each pixel on the PAIRS grid have an index that is a combination of locations and time stamp. The indexing allow quick access to data sets that are part of a global data layers and allowing to retrieve only the data of interest. PAIRS takes advantages of parallel processing framework (Hadoop) in a cloud environment to digest, curate, and analyze the data sets while being very robust and stable. The data is stored on a distributed no-SQL database (Hbase) across multiple server, data upload and retrieval is parallelized where the original analytics task is broken up is smaller areas/volume, analyzed independently, and then reassembled for the original geographical area. The differentiating aspect of PAIRS is the ability to accelerate model development across large geographical regions and spatial resolution ranging from 0.1 m up to hundreds of kilometer. System performance is benchmarked on real time automated data ingestion and retrieval of Modis and Landsat data layers. The data layers are curated for sensor error, verified for correctness, and analyzed statistically to detect local anomalies. Multi-layer query enable PAIRS to filter different data

  12. MaMiCo: Transient multi-instance molecular-continuum flow simulation on supercomputers

    Science.gov (United States)

    Neumann, Philipp; Bian, Xin

    2017-11-01

    coupling algorithmics are abstracted and incorporated in MaMiCo. Once an algorithm is set up in MaMiCo, it can be used and extended, even if other solvers are used (as soon as the respective interfaces are implemented/available). Reasons for the new version: We have incorporated a new algorithm to simulate transient molecular-continuum systems and to automatically sample data over multiple MD runs that can be executed simultaneously (on, e.g., a compute cluster). MaMiCo has further been extended by an interface to incorporate boundary forcing to account for open molecular dynamics boundaries. Besides support for coupling with various MD and CFD frameworks, the new version contains a test case that allows to run molecular-continuum Couette flow simulations out-of-the-box. No external tools or simulation codes are required anymore. However, the user is free to switch from the included MD simulation package to LAMMPS. For details on how to run the transient Couette problem, see the file README in the folder coupling/tests, Remark on MaMiCo V1.1. Summary of revisions: Open boundary forcing; Multi-instance MD sampling; support for transient molecular-continuum systems Restrictions: Currently, only single-centered systems are supported. For access to the LAMMPS-based implementation of DPD boundary forcing, please contact Xin Bian, xin.bian@tum.de. Additional comments: Please see file license_mamico.txt for further details regarding distribution and advertising of this software.

  13. Controllable scattering of photons in a one-dimensional resonator waveguide

    Science.gov (United States)

    Sun, C. P.; Zhou, L.; Gong, Z. R.; Liu, Y. X.; Nori, F.

    2009-03-01

    We analyze the coherent transport of a single photon, which propagates in a one-dimensional coupled-resonator waveguide and is scattered by a controllable two-level system located inside one of the resonators of this waveguide. Our approach, which uses discrete coordinates, unifies low and high energy effective theories for single-photon scattering. We show that the controllable two-level system can behave as a quantum switch for the coherent transport of a single photon. This study may inspire new electro-optical single-photon quantum devices. We also suggest an experimental setup based on superconducting transmission line resonators and qubits. [4pt] L. Zhou, Z.R. Gong, Y.X. Liu, C.P. Sun, F. Nori, Controllable scattering of photons in a 1D resonator waveguide, Phys. Rev. Lett. 101, 100501 (2008). URL: http://link.aps.org/abstract/PRL/v101/e100501

  14. Information filtering via biased heat conduction

    Science.gov (United States)

    Liu, Jian-Guo; Zhou, Tao; Guo, Qiang

    2011-09-01

    The process of heat conduction has recently found application in personalized recommendation [Zhou , Proc. Natl. Acad. Sci. USA PNASA60027-842410.1073/pnas.1000488107107, 4511 (2010)], which is of high diversity but low accuracy. By decreasing the temperatures of small-degree objects, we present an improved algorithm, called biased heat conduction, which could simultaneously enhance the accuracy and diversity. Extensive experimental analyses demonstrate that the accuracy on MovieLens, Netflix, and Delicious datasets could be improved by 43.5%, 55.4% and 19.2%, respectively, compared with the standard heat conduction algorithm and also the diversity is increased or approximately unchanged. Further statistical analyses suggest that the present algorithm could simultaneously identify users' mainstream and special tastes, resulting in better performance than the standard heat conduction algorithm. This work provides a creditable way for highly efficient information filtering.

  15. Kesalahan Penggunaan Kata Bantu Bilangan Bahasa Mandarin pada Siswa Indonesia Tingkat Prapemula

    Directory of Open Access Journals (Sweden)

    Ayu Trihardini

    2015-05-01

    Full Text Available The purpose of this study was to analyze Indonesian breakthrough level students’ errors in using Mandarin measure words. The collected data were the errors made by students of Prodi Pendidikan Bahasa Mandarin UNJ who attend Conversation II course (CEFR A1/breakthrough on written and oral utterance. This study used Zhou Xiaobin’s research design in Mandarin measure words error analysis, with the Carl James model of identification errors. The result of this study shows Indonesian students’ errors in using Mandarin measure words can be determined as follows: omission, misselection, misordering, and blends. Furthermore, this study proves that there are systematic errors made by students with different mother tongue and at the same level of learning Mandarin. The research results can be used to develop Mandarin measure words teaching techniques based on error analysis.

  16. Shock Ignition of Thermonuclear Fuel with High Areal Density

    International Nuclear Information System (INIS)

    Betti, R.; Zhou, C. D.; Anderson, K. S.; Theobald, W.; Solodov, A. A.; Perkins, L. J.

    2007-01-01

    A novel method by C. Zhou and R. Betti [Bull. Am. Phys. Soc. 50, 140 (2005)] to assemble and ignite thermonuclear fuel is presented. Massive cryogenic shells are first imploded by direct laser light with a low implosion velocity and on a low adiabat leading to fuel assemblies with large areal densities. The assembled fuel is ignited from a central hot spot heated by the collision of a spherically convergent ignitor shock and the return shock. The resulting fuel assembly features a hot-spot pressure greater than the surrounding dense fuel pressure. Such a nonisobaric assembly requires a lower energy threshold for ignition than the conventional isobaric one. The ignitor shock can be launched by a spike in the laser power or by particle beams. The thermonuclear gain can be significantly larger than in conventional isobaric ignition for equal driver energy

  17. Shock ignition of thermonuclear fuel with high areal density.

    Science.gov (United States)

    Betti, R; Zhou, C D; Anderson, K S; Perkins, L J; Theobald, W; Solodov, A A

    2007-04-13

    A novel method by C. Zhou and R. Betti [Bull. Am. Phys. Soc. 50, 140 (2005)] to assemble and ignite thermonuclear fuel is presented. Massive cryogenic shells are first imploded by direct laser light with a low implosion velocity and on a low adiabat leading to fuel assemblies with large areal densities. The assembled fuel is ignited from a central hot spot heated by the collision of a spherically convergent ignitor shock and the return shock. The resulting fuel assembly features a hot-spot pressure greater than the surrounding dense fuel pressure. Such a nonisobaric assembly requires a lower energy threshold for ignition than the conventional isobaric one. The ignitor shock can be launched by a spike in the laser power or by particle beams. The thermonuclear gain can be significantly larger than in conventional isobaric ignition for equal driver energy.

  18. Estimating Stochastic Volatility Models using Prediction-based Estimating Functions

    DEFF Research Database (Denmark)

    Lunde, Asger; Brix, Anne Floor

    to the performance of the GMM estimator based on conditional moments of integrated volatility from Bollerslev and Zhou (2002). The case where the observed log-price process is contaminated by i.i.d. market microstructure (MMS) noise is also investigated. First, the impact of MMS noise on the parameter estimates from......In this paper prediction-based estimating functions (PBEFs), introduced in Sørensen (2000), are reviewed and PBEFs for the Heston (1993) stochastic volatility model are derived. The finite sample performance of the PBEF based estimator is investigated in a Monte Carlo study, and compared...... to correctly account for the noise are investigated. Our Monte Carlo study shows that the estimator based on PBEFs outperforms the GMM estimator, both in the setting with and without MMS noise. Finally, an empirical application investigates the possible challenges and general performance of applying the PBEF...

  19. A micro-CT research on early faience:a case study of Peng state faience

    International Nuclear Information System (INIS)

    Gu Zhou; Yang Yimin; Wang Ning; Wang Changsui; Xie Yaoting; Xiao Tiqiao

    2012-01-01

    Faience is supposed to be the precursor of ancient glass. Studies on Chinese faience are of help in understanding the origin and development of Chinese ancient glass. In this paper, non-destructive methods of SR-μCT, XRD and EDXRF are used to analyze a faience bead from Peng state in Western Zhou period (BC1046-BC771). The results show that the bead body is composed of micro quartz particles, and the body is denser than that of Western faience. The manufacture procedure can be deduced as follows: based on a cylinder core, the quartz particles were piled to form the body, which was then glazed and heated; after that the core was stripped. This technology was influenced by the bronze and protoporcelain production. Micro CT has great potential to study microstructure of ancient faience. (authors)

  20. Synchrotron X-ray diffraction and imaging of ancient Chinese bronzes

    International Nuclear Information System (INIS)

    Young, M.L.; Dunand, D.C.; Casadio, F.; Schnepp, S.; Almer, J.; Haeffner, D.R.

    2006-01-01

    High-energy synchrotron X-ray diffraction and imaging experiments were performed at the Advanced Photon Source on two ancient Chinese bronzes from the Art Institute of Chicago with the goal to nondestructively study their microstructure. The first object, a bronze fragment from an early Western Zhou dynasty vessel (Hu, 11th/10th century B.C.), was investigated with spatially-resolved diffraction to reveal the depth and composition of the surface corrosion layer as well as the composition and grain size of the underlying bronze core. The second object, a bronze dagger-axe (Ge, 3rd/2nd century B.C.) with a silver-inlaid sheath, was studied under both diffraction and imaging conditions. It was found to have been cast as a single object, answering longstanding scholars' questions on whether the ceremonial object concealed an interior blade. (orig.)

  1. Pole orientation of 16 Psyche by two independent methods

    Science.gov (United States)

    Tedesco, E. F.; Taylor, R. C.

    1985-01-01

    Nineteen new lightcurves of 16 Psyche are presented along with a pole orientation derived using two independent methods, namely, photometric astrometry and magnitude-amplitude-shape-aspect. The pole orientations found using these two methods agree to within 4 deg. The results from applying photometric astrometry were prograde rotation, a sidereal period of 0.1748143 days + or - 0.0000003 days, and a pole at longitude 223 deg and latitude +37 deg, with an uncertainty of 10 deg, and, from applying magnitude-amplitude-shape-aspect a pole at 220 + or - 1 deg, +40 + or - 4 deg, and a modeled triaxial ellipsoid shape (a greater than b greater than c) and a/b = 1.33 + or - 0.07. The discrepancy between the high-pole latitude found here and the low latitudes reported by Lupishko et al. (1982) and Zhou and Yang (1982) is discussed.

  2. Comprehensive geobiological characterization of a bituminous carbonate facies with Ediacara-type fossils (Shibantan Member, South China)

    Science.gov (United States)

    Duda, Jan-Peter; Blumenberg, Martin; Thiel, Volker; Simon, Klaus; Zhu, Maoyan; Reitner, Joachim

    2015-04-01

    13C = -31.7 to -36.3o VPDB) indicate a significant withdrawal of 12C by primary producers that thrived within the microbial mats. At the same time, sulphurised biomarkers in the bitumen and HyPy-treated extraction residue hint at organic matter decomposition and concomitant sulphide production by sulphate-reducing bacteria. Given the sedimentological evidence for periodical ventilation of the water column by storms, sulphide oxidising bacteria were possibly favoured whenever oxygen became available at the sediment-water interface. Taken together, the environments in which the microbial-mat-associated biota including Ediacara-type fossils throve were highly dynamic due to a complex interplay of geological and biological processes. References Chen Z., Zhou C., Xiao S., Wang W., Guan C., Hua H., Yuan X., 2014. New Ediacara fossils preserved in marine limestone and their ecological implications. Scientific Reports, 4 Ding Q. and Chen Y., 1981. Discovery of soft metazoan from the Sinian System along eastern Yangtze Gorge, Hubei. Journal of the Wuhan College of Geology, 2, 53-57. Shen, B., Xiao S., Zhou C., Yuan X., 2009. Yangtziramulus zhangi New Genus and Species, a Carbonate-Hosted Macrofossil from the Ediacaran Dengying Formation in the Yangtze Gorges Area, South China. Journal of Paleontology, 83(4): 575-587. Sun W., 1986. Late precambrian pennatulids (sea pens) from the eastern Yangtze Gorge, China: Paracharnia gen. nov. Precambrian Research, 31(4), 361-375. Xiao S., Shen B., Zhou C., Xie G., Yuan X., 2005. A uniquely preserved Ediacaran fossil with direct evidence for a quilted bodyplan. Proceedings of the National Academy of Sciences of the United States of America, 102(29), 10227-10232.

  3. Performance of a hydrogen/deuterium polarized gas target in a storage ring

    International Nuclear Information System (INIS)

    Buuren, L.D. van; Szczerba, D.; Brand, J.F.J. van den; Bulten, H.J.; Ferro-Luzzi, M.; Klous, S.; Kolster, H.; Lang, J.; Mul, F.A.; Poolman, H.R.; Simani, M.C.

    2001-01-01

    The performance of a high-density polarized hydrogen/deuterium gas target internal to a medium-energy electron storage ring is presented. Compared to our previous electron scattering experiments with tensor-polarized deuterium at NIKHEF (Zhou et al., Nucl. Instr. and Meth. A 378 (1996) 40; Ferro-Luzzi et al., Phys. Rev. Lett. 77 (1996) 2630; Van den Brand et al., Phys. Rev. Lett. 78 (1997) 1235; Bouwhuis et al., Phys. Rev. Lett. 82 (1999) 687; Zhou et al., Phys. Rev. Lett. 82 (1999) 687) the target figure of merit, (polarization) 2 xluminosity, was improved by more than an order of magnitude. The target density was increased by upgrading the flux of nuclear-polarized atoms injected into the storage cell and by using a longer (60 cm) and colder (∼70 K) storage cell. A maximal target thickness of 1.2 (1.1)±0.1x10 14 nuclei/cm 2 was achieved with deuterium (hydrogen). With typical beam currents of 110 mA, this corresponds to a luminosity of about 8.4 (7.8)±0.8x10 31 e - nuclei cm -2 s -1 . By reducing the molecular background and using a stronger target guide field, a higher polarization was achieved. The target was used in combination with a 720 MeV polarized electron beam stored in the AmPS ring (NIKHEF) to measure spin observables in electron-proton and electron-deuteron scattering. Scattered electrons were detected in a large acceptance magnetic spectrometer. Ejected hadrons were detected in a single time-of-flight scintillator array. The product of beam and target vector polarization, P e P t , was determined from the known spin-correlation parameters of e'p quasi-elastic (or elastic) scattering. With the deuterium (hydrogen) target, values up to P e P t =0.49±0.03 (0.32±0.03) were obtained with an electron beam polarization of P e =0.62±0.04 (0.56±0.03) as measured with a Compton backscattering polarimeter (Passchier et al., Nucl. Instr. and Meth. A 414 (1998) 4988). From this, we deduce a cell-averaged target polarization of P t =0.78±0.07 (0.58±0

  4. Valores compositivos fundamentales del jardín privado chino o la mirada urbana sobre el paisaje a lo largo de su historia hasta la Revolución de 1949

    Directory of Open Access Journals (Sweden)

    Andrea González

    2017-07-01

    Full Text Available La historia del jardín en la cultura china se remonta a la historia de las dinastías Shang y Zhou y continúa a lo largo de las dinastías Qin, Han, Tang, Song, Yuan, Ming y Qing hasta la llegada de la República China y la República Popular de China. Los valores artísticos y paisajísticos del jardín en esta cultura se desarrollaron de forma paralela a la historia de la nación y tuvieron una influencia directa sobre la arquitectura doméstica y sobre el jardín de naciones cercanas como Japón. Sus influencias se reflejaron en teorías como el Fengshui y las leyes geománticas y generaron a lo largo de los siglos valores compositivos propios del jardín chino. La conclusion de esta investigación consiste en una asimilación de lo estudiado y en detallar los aspectos compositivos y de diseño, tales como el centro, el límite, el element de la montaña, el vacío, el agua, o el teatro, entre otros. ABSTRACT: This essay starts with a brief description of the history of the garden in the East and introduces the reader into the Chinese culture starting with the Shang and Zhou Dynasties and continuing with the historical development through the Qin, Han, Tang, Song, Yuan, Ming and Qing dynasties and the arrival of the Republic of China and the People’s Republic of China. In this essay the artistic and landscape values of Chinese culture are described alongside the history of the garden and the influences on the Japanese garden they have had from ancient times until today. These are explained alongside the art of Fengshui, geomantic laws and the main elements that compose the Chinese garden. The conclusion entails a brief assimilation of what has been deduced from the main study. In this part of the essay the compositive and design aspects of the Chinese garden are described, aspects such as centre, limit, the element of the mountain, emptiness, water, and the theatre, among other.

  5. Altered spontaneous brain activity pattern in patients with high myopia using amplitude of low-frequency fluctuation: a resting-state fMRI study

    Directory of Open Access Journals (Sweden)

    Huang X

    2016-11-01

    Full Text Available Xin Huang,1,2,* Fu-Qing Zhou,3,* Yu-Xiang Hu,1 Xiao-Xuan Xu,1 Xiong Zhou,4 Yu-Lin Zhong,1 Jun Wang,4 Xiao-Rong Wu1 1Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, 2Department of Ophthalmology, The First People’s Hospital of Jiujiang City, Jiujiang, 3Department of Radiology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Medical Imaging Research Institute, 4Second Department of Respiratory Disease, Jiangxi Provincial People’s Hospital, Nanchang, Jiangxi, People’s Republic of China *These authors contributed equally to this work Objective: Many previous reports have demonstrated significant neural anatomy changes in the brain of high myopic (HM patients, whereas the spontaneous brain activity changes in the HM patients at rest are not well studied. Our objective was to use amplitude of low-frequency fluctuation (ALFF method to investigate the changes in spontaneous brain activity in HM patients and their relationships with clinical features. Methods: A total of 38 patients with HM (17 males and 21 females and 38 healthy controls (HCs (17 males and 21 females closely matched in age, sex, and education underwent resting-state functional magnetic resonance imaging scans. The ALFF method was used to assess local features of spontaneous brain activity. The relationship between the mean ALFF signal values in many brain regions and the clinical features in HM patients was calculated by correlation analysis. Results: Compared with HCs, the HM patients had significantly lower ALFF in the right inferior and middle temporal gyrus, left middle temporal gyrus, left inferior frontal gyrus/putamen, right inferior frontal gyrus/putamen/insula, right middle frontal gyrus, and right inferior parietal lobule and higher ALFF values in the bilateral midcingulate cortex, left postcentral gyrus, and left precuneus/inferior parietal lobule. However, no relationship was found between the mean ALFF

  6. Tau-charm factory..

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1995-10-15

    In addition to hearing the latest experimental and theoretical developments at the 17th International Symposium on Lepton Photon Interactions in Beijing, delegates were brought up-to-date on the substantial progress towards the realization of a Tau-Charm Factory in the Chinese capital. Opening the Symposium, Zhou Guangzhao, President of the Chinese Academy of Sciences, expressed a commitment of the Chinese government to basic research and its interest in the continuing development high energy physics in China. Following the very successful construction and operation of Beijing's Electron-Positron Collider, BEPC, the Chinese government has provided 5M yuan ($US 600,000) for a feasibility study by the end of 1996 for a Tau-Charm Factory at Beijing's Institute of High Energy Physics (IHEP). Professor Zhou expressed his belief that, once approved, such a factory would greatly enhance high energy physics in China. He warmly welcomed international collaboration both in the construction of the accelerator and in the experimental programme. His comments were reinforced in the following welcome speech by IHEP Director Zheng Zhipeng. Conference delegates had the opportunity to inspect the BEPC injector and collider, built almost entirely by Chinese industry. The International Committee for Future Accelerators (ICFA) met during the Symposium, with Tau- Charm Factory business on the agenda. In his subsequent report, ICFA Chairman John Peoples said that a Tau-Charm Factory provides a unique experimental environment for the precision studies of tau, charm and light quark-gluon spectroscopy, and that some issues in these fields are not satisfactorily addressed solely by B Factories or fixed-target experiments. The committee expressed a strong interest in seeing a Tau-Charm Factory built and noted the serious interest, especially in China, and looks forward to operation and exploitation by the international physics community. In their Beijing summary talks, both Sam Ting and T

  7. The imaging assessment and specific endograft design for the endovascular repair of ascending aortic dissection

    Directory of Open Access Journals (Sweden)

    Zhang Y

    2016-07-01

    Full Text Available Yepeng Zhang,1 Hanfei Tang,1 JianPing Zhou,2 Zhao Liu,1 Changjian Liu,1 Tong Qiao,1 Min Zhou1 1Department of Vascular Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 2Department of General Surgery, Yixin People’s Hospital, Yixin, People’s Republic of China Background: Endovascular option has been proposed for a very limited and selected number of Stanford type A aortic dissection (TAAD patients. We have performed a computed tomography (CT-based TAAD study to explore appropriate endograft configurations for the ascending aortic pathology. Methods: TAAD patients treated with optimal CT scans were retrospectively reviewed, and their entry tears (ETs were identified using three-dimensional and multiplanar reconstructions in an EndoSize workstation. After generating a centerline of flow, measurements, including numerous morphologic characteristics of anatomy, were evaluated and a selected subset of patients were determined to be suitable for endovascular treatments. Proximal diameter and distal diameter of endograft were selected based on diameters measured at the ET level and at the innominate artery (IA level, with 10% oversizing with respect to the true lumen, but not exceeding the original aortic diameter. The length of the endograft was determined by the distance from the sinotubular junction to IA. Results: This study covered 126 TAAD patients with primary ET in ascending aorta, among which, according to the assumed criteria, 48 (38.1% patients were deemed to be suitable for endovascular treatment. The diameters of ascending aorta from the sinotubular junction to the IA level presented a downward trend, and the proximal diameters differed significantly from distal diameters of the endograft for TAAD (39.9 versus 36.2 mm, P<0.01, implying that the conical endograft might be compatible with the ascending pathology. In the ascending aorta, lengths of the endograft should be 50, 60, 70, 80, and 90 mm in five

  8. Dexmedetomidine attenuates persistent postsurgical pain by upregulating K+–Cl− cotransporter-2 in the spinal dorsal horn in rats

    Directory of Open Access Journals (Sweden)

    Dai S

    2018-05-01

    Full Text Available Shuhong Dai,1 Yu Qi,1 Jie Fu,1 Na Li,1 Xu Zhang,1 Juan Zhang,2 Wei Zhang,2 Haijun Xu,1 Hai Zhou,1 Zhengliang Ma2 1Department of Anesthesiology, XuZhou Central Hospital, Xuzhou, China; 2The Affiliated Nanjing Drum Tower Hospital, Medical School, Nanjing University, Nanjing, China Background: Dexmedetomidine (DEX could have an analgesic effect on pain transmission through the modulation of brain-derived neurotrophic factor (BDNF. In addition, KCC2-induced shift in neuronal Cl- homeostasis is crucial for postsynaptic inhibition mediated by GABAA receptors. Accumulating evidence shows that nerve injury, peripheral inflammation and stress activate the spinal BDNF/TrkB signal, which results in the downregulation of KCC2 transport and expression, eventually leads to GAGAergic disinhibition and hyperalgesia. The aim of this experiment was to explore the interaction between DEX and KCC2 at a molecular level in rats in the persistent postsurgical pain (PPSP. Methods: PPSP in rats was evoked by the skin/muscle incision and retraction (SMIR. Mechanical hypersensitivity was assessed with the Dynamic Plantar Aesthesiometer. Western blot and immunofluorescence assay were used to assess the expressions of related proteins. Results: In the first part of our experiment, the results revealed that the BDNF/TrkB-KCC2 signal plays a critical role in the development of SMIR-evoked PPSP; the second part showed that intraperitoneal administrations of 40 µg/kg DEX at 15 min presurgery and 1 to 3 days post-surgery significantly attenuated SMIR-evoked PPSP. Simultaneously, SMIR-induced KCC2 downregulation was partly reversed, which coincided with the inhibition of the BDNF/TrkB signal in the spinal dorsal horn. Moreover, intrathecal administrations of KCC2 inhibitor VU0240551 significantly reduced the analgesic effect of DEX on SMIR-evoked PPSP. Conclusion: The results of our study indicated that DEX attenuated PPSP by restoring KCC2 function through reducing BDNF

  9. Phase equilibria modelling and zircon dating for Precambrian metapelites from Xinghuadukou Group in Lvlin Forest of Erguna Massif, NE China

    Science.gov (United States)

    Xu, Jiulei; Zheng, Changqing; Tajcmanova, Lucie; Zhong, Xin; Xu, Xuechun; Han, Xiaomeng; Wang, Zhaoyuan

    2017-04-01

    Xinghuadukou Group, the basement metamorphic complex of Erguna Massif in NE China, is considered to be Mesoproterozoic with Sm-Nd age of 1157±32 Ma. However, the new zircon data from these metamorphic supracrustal rocks in Lvlin Forest show that they formed in Neoproterozoic with the age of 800 Ma. Old zircon age with 2.5 Ga, 2.0 Ga and 1.8 Ga, indicate that the Erguna Massif had an affinity to both Columbia and Rodinia continents. Furthermore, we also present 500 Ma metamorphic age in micashists and 500 Ma age of adjacent granitoids that might have thermally influenced its surrounding. No detailed studies have been undertaken on the metamorphic evolution of the Xinghuadukou Complex. The typical paragneissic mineral assemblage of garnet sillimanite mica schist is Grt+Sil+Bt+Mus+Qtz±Kfs. (Zhou et al., 2011) proposed that the Xinghuadukou Complex appears to have undergone similar granulite facies metamorphic conditions based on the similarity of mineral assemblages to the Mashan Complex in the Jiamusi Massif, NE China. However, the new phase equilibria modelling result shows that these rocks are high amphibolite facies product with 650℃. We can easily find K-feldspar formed by partial melting due to the consuming of muscovite. Also the remaining muscovite is directly connected with a fluid channel in thin sections which indicate that the remaining muscovite formed from retrograde with the existence of fluid. The zoned garnet has low MgO and high CaO content in rims and high MgO and low CaO content in core. It seems that this garnet has high pressure and low temperature (HP-LT) in rims and low pressure and high temperature (LP-HT) in core which would point to an anti-clockwise metamorphic evolution. Zhou, J.B., Wilde, S.A., Zhang, X.Z., Zhao, G.C., Liu, F.L., Qiao, D.W., Ren, S.M. and Liu, J.H., 2011b. A> 1300km late Pan-African metamorphic belt in NE China: new evidence from the Xing'an block and its tectonic implications. Tectonophysics, 509(3): 280-292.

  10. Tau-charm factory..

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    In addition to hearing the latest experimental and theoretical developments at the 17th International Symposium on Lepton Photon Interactions in Beijing, delegates were brought up-to-date on the substantial progress towards the realization of a Tau-Charm Factory in the Chinese capital. Opening the Symposium, Zhou Guangzhao, President of the Chinese Academy of Sciences, expressed a commitment of the Chinese government to basic research and its interest in the continuing development high energy physics in China. Following the very successful construction and operation of Beijing's Electron-Positron Collider, BEPC, the Chinese government has provided 5M yuan ($US 600,000) for a feasibility study by the end of 1996 for a Tau-Charm Factory at Beijing's Institute of High Energy Physics (IHEP). Professor Zhou expressed his belief that, once approved, such a factory would greatly enhance high energy physics in China. He warmly welcomed international collaboration both in the construction of the accelerator and in the experimental programme. His comments were reinforced in the following welcome speech by IHEP Director Zheng Zhipeng. Conference delegates had the opportunity to inspect the BEPC injector and collider, built almost entirely by Chinese industry. The International Committee for Future Accelerators (ICFA) met during the Symposium, with Tau- Charm Factory business on the agenda. In his subsequent report, ICFA Chairman John Peoples said that a Tau-Charm Factory provides a unique experimental environment for the precision studies of tau, charm and light quark-gluon spectroscopy, and that some issues in these fields are not satisfactorily addressed solely by B Factories or fixed-target experiments. The committee expressed a strong interest in seeing a Tau-Charm Factory built and noted the serious interest, especially in China, and looks forward to operation and exploitation by the international physics community. In their Beijing summary talks, both Sam Ting

  11. Advanced Materials and Processing 2010

    Science.gov (United States)

    Zhang, Yunfeng; Su, Chun Wei; Xia, Hui; Xiao, Pengfei

    2011-06-01

    [symbol]Si-based alloy with titanium addition / S. K. Wang ... [et al.] -- Improvement of magnetic properties and size of directly casted Nd-Fe-B bulk magnets by Ti/Zr cosubstitutions / H. W. Chang ... [et al.] -- Wear behavior of the ceramic coatings on the Al6061 alloy prepared by plasma electrolytic oxidation / Jin Long Bian ... [et al.] -- Hydrogels with rapid thermal-responsibility by using liquid crystallite as template / Qingsong Zhang ... [et al.] -- The effects of TiO[symbol] buffer layer in carbon nanotubes growth on Ti substrate by thermal chemical vapor deposition and their electrochemical properties / Yong-Hwan Gwon ... [et al.] -- Phase transfer catalytic synthesis of 4-Benzyloxyl-3-Methoxylbenzaldehyde-Copolystyrene resin / Qiang Huang and Baozhong Zheng -- Compressive behaviour of nanocrystallilne Mg-5%Al alloys / H. Diao ... [et al.] -- Predicting the formation enthalpies of Al-Ga-In, Al-Ga-Sn, Cd-Ga-Sn and Ga-Sn-Zn liquid alloys by molecular interaction volume model / Hongwei Yang, Dongping Tao and Qingmei Yuan -- Low-temperature preparation and properties of high activity anatase TiO[symbol] aqueous sols / Qingju Liu ... [et al.] -- Effects of Ge mole fraction on electrical characteristics of strained SiGe channel p-MOSFET / Zhou Yang ... [et al.] -- Evaluation of oxidation and mechanical properties of the nano-sized WC-10%Nicrobraz composites consolidated by high frequency induction heated sintering / Duck-Soo Kang ... [et al.] -- Effect of ECAP on the high-temperature compressive deformation behavior of LY12 aluminum alloys / Qing-Wei Jiang ... [et al.] -- Surface energy effect on polymers adhesive bonding at room temperature / Yingxia Jin ... [et al.] -- Annealing effects on selfassembled Ge/Si (100) islands prepared by ion beam sputtering / Jie Yang ... [et al.] -- Effect of Gd on the microstructures and corrosion behaviors of magnesium alloy Mg-8.0Al-1.0Zn / Li Lei, Xie Shuisheng and Huang Guojie -- Synthesis, characterization and sensing properties of Perovskite

  12. Izumo and the East Asian Bronze Culture%出云与东亚的青铜文化

    Institute of Scientific and Technical Information of China (English)

    王巍

    2003-01-01

    The origin of bronzes in Yayoi Japan can be traced to their counterparts in Xia-Shang-Zhou China. It must have happened that ancient Chinese bronze weapons and small bells used aspractical implements were first spread into Japan through northeastern China and the Korean Peninsulaand then developed gradually into bronzes exclusively for sacrificial use. Among the bronzes unearthed inbatches from hoards in the Izumo area within the coastland of the Sea of Japan, the spearheads may havebeen made in the north of Kyushu, the small bells must have come from the Kinai region, and the over300 swords were probably local products. The repeated discovery of Yayoi bronze hoards in the Izumoarea suggests that this region was absolutely not an unpopulated land. On the contrary, as a very im-portant district, it should be fully affirmed to have played a considerable role in the development of an-cient Japanese history.

  13. Nanotoxicity: how the body develops a way to reduce the toxicity of carbon nanotubes.

    Science.gov (United States)

    Riehemann, Kristina

    2012-07-09

    The interaction of nanoparticles with cells and organisms are often the focus of biomedical, material, and environmental research. This article highlights a paper by Yuliang Zhao, Chunying Chen, Ruhong Zhou, and co-workers (Proc. Natl. Acad. Sci. USA 2011, 108, 16968), which brings a new aspect to the discussion about purpose and mechanisms underlying the reaction of an organism with nanoparticles. The interactions of carbon nanotubes with cells were investigated with regard to the defense mechanisms of the body against foreign materials developed during evolution. Such mechanisms are not only important for nanotoxicity research, but also for targeting nanoparticles in medical applications. The cited article thus gives a new focus to an important aspect of nanotechnology, which will determine the application aspects of this technology in future: the approach of biological systems to nanosized particles. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. True random number generation from mobile telephone photo based on chaotic cryptography

    International Nuclear Information System (INIS)

    Zhao Liang; Liao Xiaofeng; Xiao Di; Xiang Tao; Zhou Qing; Duan Shukai

    2009-01-01

    A cheap, convenient and universal TRNG based on mobile telephone photo for producing random bit sequence is proposed. To settle the problem of sequential pixels and comparability, three chaos-based approaches are applied to post-process the generated binary image. The random numbers produced by three users are tested using US NIST RNG statistical test software. The experimental results indicate that the Arnold cat map is the fastest way to generate a random bit sequence and can be accepted on general PC. The 'MASK' algorithm also performs well. Finally, comparing with the TRNG of Hu et al. [Hu Y, Liao X, Wong KW, Zhou Q. A true random number generator based on mouse movement and chaotic cryptography. Chaos, Solitons and Fractals 2007. doi: 10.1016/j.chaos.2007.10.022] which is presented by Hu et al., many merits of the proposed TRNG in this paper has been found.

  15. Modified planar functions and their components

    DEFF Research Database (Denmark)

    Anbar Meidl, Nurdagül; Meidl, Wilfried Meidl

    2017-01-01

    functions in odd characteristic as a vectorial bent function. We finally point out that though these components behave somewhat different than the multivariate bent4 functions, they are bent or semibent functions shifted by a certain quadratic term, a property which they share with their multivariate......Zhou ([20]) introduced modified planar functions in order to describe (2n; 2n; 2n; 1) relative difference sets R as a graph of a function on the finite field F2n, and pointed out that projections of R are difference sets that can be described by negabent or bent4 functions, which are Boolean...... functions given in multivariate form. One of the objectives of this paper is to contribute to the understanding of these component functions of modified planar functions. Moreover, we obtain a description of modified planar functions by their components which is similar to that of the classical planar...

  16. Exact solution for a two-phase Stefan problem with variable latent heat and a convective boundary condition at the fixed face

    Science.gov (United States)

    Bollati, Julieta; Tarzia, Domingo A.

    2018-04-01

    Recently, in Tarzia (Thermal Sci 21A:1-11, 2017) for the classical two-phase Lamé-Clapeyron-Stefan problem an equivalence between the temperature and convective boundary conditions at the fixed face under a certain restriction was obtained. Motivated by this article we study the two-phase Stefan problem for a semi-infinite material with a latent heat defined as a power function of the position and a convective boundary condition at the fixed face. An exact solution is constructed using Kummer functions in case that an inequality for the convective transfer coefficient is satisfied generalizing recent works for the corresponding one-phase free boundary problem. We also consider the limit to our problem when that coefficient goes to infinity obtaining a new free boundary problem, which has been recently studied in Zhou et al. (J Eng Math 2017. https://doi.org/10.1007/s10665-017-9921-y).

  17. SPOT-ligand 2: improving structure-based virtual screening by binding-homology search on an expanded structural template library.

    Science.gov (United States)

    Litfin, Thomas; Zhou, Yaoqi; Yang, Yuedong

    2017-04-15

    The high cost of drug discovery motivates the development of accurate virtual screening tools. Binding-homology, which takes advantage of known protein-ligand binding pairs, has emerged as a powerful discrimination technique. In order to exploit all available binding data, modelled structures of ligand-binding sequences may be used to create an expanded structural binding template library. SPOT-Ligand 2 has demonstrated significantly improved screening performance over its previous version by expanding the template library 15 times over the previous one. It also performed better than or similar to other binding-homology approaches on the DUD and DUD-E benchmarks. The server is available online at http://sparks-lab.org . yaoqi.zhou@griffith.edu.au or yuedong.yang@griffith.edu.au. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  18. Irreducible multiqutrit correlations in Greenberger-Horne-Zeilinger-type states

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Fu-Lin [Physics Department, School of Science, Tianjin University, Tianjin 300072 (China); Chen, Jing-Ling [Theoretical Physics Division, Chern Institute of Mathematics, Nankai University, Tianjin, 300071 (China); Centre for Quantum Technologies, National University of Singapore, 3 Science Drive 2, Singapore 117543 (Singapore)

    2011-12-15

    Following the idea of the continuity approach by D. L. Zhou [Phys. Rev. Lett. 101, 180505 (2008)], we obtain the degrees of irreducible multiparty correlations in two families of n-qutrit Greenberger-Horne-Zeilinger-type states. For the pure states in one of the families, the irreducible 2-party, n-party, and (n-m)-party (0

  19. Irreducible multiqutrit correlations in Greenberger-Horne-Zeilinger-type states

    International Nuclear Information System (INIS)

    Zhang, Fu-Lin; Chen, Jing-Ling

    2011-01-01

    Following the idea of the continuity approach by D. L. Zhou [Phys. Rev. Lett. 101, 180505 (2008)], we obtain the degrees of irreducible multiparty correlations in two families of n-qutrit Greenberger-Horne-Zeilinger-type states. For the pure states in one of the families, the irreducible 2-party, n-party, and (n-m)-party (0< m< n-2) correlations are nonzero, which is different from the n-qubit case. We also derive the correlation distributions in the n-qutrit maximal slice state, which can be uniquely determined by its (n-1)-qutrit-reduced density matrices among pure states. It is proved that there is no irreducible n-qutrit correlation in the maximal slice state. This enlightens us to give a discussion about how to characterize the pure states with irreducible n-party correlation in arbitrarily high-dimensional systems by the way of the continuity approach.

  20. Primed for Discovery: Atomic-Resolution Cryo-EM Structure of a Reovirus Entry Intermediate

    Directory of Open Access Journals (Sweden)

    Shane D. Trask

    2010-06-01

    Full Text Available A recently solved structure of the aquareovirus virion (Zhang, X; Jin, L.; Fang, Q; Hui, W.H.; Zhou Z.H. 3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry. Cell 2010, 141, 472-482 [1] provides new insights into the order of entry events, as well as confirming and refining several aspects of the entry mechanism, for aquareovirus and the related orthoreovirus. In particular, the structure provides evidence of a defined order for the progressive proteolytic cleavages of myristoylated penetration protein VP5 that prime the virion for membrane penetration. These observations reinforce the concept that, much like enveloped viruses, nonenveloped virions often undergo priming events that lead to a meta-stable state, preparing the virus for membrane penetration under the appropriate circumstances. In addition, this and other recent studies highlight the increasing power of electron cryomicroscopy to analyze large, geometrically regular structures, such as icosahedral viruses, at atomic resolution.

  1. Water use efficiency and integrated water resource management for river basin

    Science.gov (United States)

    Deng, Xiangzheng; Singh, R. B.; Liu, Junguo; Güneralp, Burak

    Water use efficiency and management have attracted increasing attention as water has become scare to challenge the world's sustainable development. Water use efficiency is correlated to the land use and cover changes (LUCC), population distribution, industrial structure, economic development, climate changes, and environmental governance. These factors significantly alter water productivity for water balance through the changes in natural environment and socio-economic system (Wang et al., 2015b). Consequently, dynamics of water inefficiency lower the social welfare of water allocation (Wang et al., 2015b), and induce water management alternation interactively and financially (Wang et al., 2015a). This triggers on actual water price changes through both natural resource and socioeconomic system (Zhou et al., 2015). Therefore, it is very important to figure out a mechanism of water allocation in the course of LUCC (Jin et al., 2015) at a global perspective (Zhao et al., 2015), climate and economic changes of ecosystem service at various spatial and temporal scales (Li et al., 2015).

  2. A panel data parametric frontier technique for measuring total-factor energy efficiency: An application to Japanese regions

    International Nuclear Information System (INIS)

    Honma, Satoshi; Hu, Jin-Li

    2014-01-01

    Using the stochastic frontier analysis model, we estimate TFEE (total-factor energy efficiency) scores for 47 regions across Japan during the years 1996–2008. We extend the cross-sectional stochastic frontier model proposed by Zhou et al. (2012) to panel data models and add environmental variables. The results provide not only the TFEE scores, in which statistical noise is taken into account, but also the determinants of inefficiency. The three stochastic TFEE scores are compared with a TFEE score derived using data envelopment analysis. The four TFEE scores are highly correlated with one another. For the inefficiency estimates, higher manufacturing industry shares and wholesale and retail trade shares correspond to lower TFEE scores. - Highlights: • This study estimates total-factor energy efficiency of Japanese regions using the stochastic frontier analysis model. • Determinants of inefficiency are also estimated. • The higher the manufacturing share and wholesale and retail trade share, the lower the energy efficiency

  3. Contents, Abstracts and Keywords

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The Ethnic Minority Rights from the Angle of Multiculturalism Zhou Shaoqing(1) Abstract: Historically, multiculturalism was closely related to the ethnic minority rights. Currently there are two features in the research on multiculturalism and the ethnic minority rights. One is that most researchers do not strictly distinguish the different dimensions of multiculturalism, the other is that they tend to regard only multiculturalism as a theory of the ethnic minority rights, and less attach its importance to the multi-ethnie state construction. The thesis argues that multiculturalism has at least five dimensions, such as fact, theory, ideology, policy, and normative principle. The concept of the ethnic minority rights in each dimension has its special meaning and effect. The ethnic minority rights protection and the multi-ethnic state construction are two different aspects in the same historical process. Multiculturalism is not only a theory of the ethnic minority rights, but also an important supportive theory of the multi-ethnic state construction.

  4. Inverse spinel ZnFe2O4 nanoparticles synthesized by ion implantation and post-annealing: An investigation using X-ray spectroscopy and magneto-transport

    International Nuclear Information System (INIS)

    Zhou Shengqiang; Potzger, K.; Buerger, D.; Kuepper, K.; Helm, M.; Fassbender, J.; Schmidt, H.

    2009-01-01

    Noncrystalline ZnFe 2 O 4 has been investigated intensively due to the drastic difference in cation distribution compared with bulk materials. We previously synthesized ZnFe 2 O 4 nanoparticles by ion implantation and post-annealing [S. Zhou, K. Potzger, H. Reuther, G. Talut, F. Eichhorn, J. von Borany, W. Skorupa, M. Helm, J. Fassbender, J. Phys. D - Appl. Phys. 40 (2007) 964]. These ZnFe 2 O 4 nanocrystals are crystallographically oriented inside the ZnO matrix and show a hysteretic behavior upon magnetization reversal at 5 K. Their magnetic properties are explained by assuming that Fe 3+ ions partially occupy tetrahedral sites. In this paper an X-ray spectroscopic and magneto-transport investigation on ZnFe 2 O 4 nanocrystals in a ZnO matrix will be presented. The occupation of Fe 3+ at tetrahedral sites has been directly proved. A positive magnetoresistance (MR) effect is observed and is attributed to ordinary MR.

  5. Physical consequences of the mitochondrial targeting of single-walled carbon nanotubes probed computationally

    Science.gov (United States)

    Chistyakov, V. A.; Zolotukhin, P. V.; Prazdnova, E. V.; Alperovich, I.; Soldatov, A. V.

    2015-06-01

    Experiments by F. Zhou and coworkers (2010) [16] showed that mitochondria are the main target of the cellular accumulation of single-walled carbon nanotubes (SWCNTs). Our in silico experiments, based on geometrical optimization of the system consisting of SWCNT+proton within Density Functional Theory, revealed that protons can bind to the outer side of SWCNT so generating a positive charge. Calculation results allow one to propose the following mechanism of SWCNTs mitochondrial targeting. SWCNTs enter the space between inner and outer membranes of mitochondria, where the excess of protons has been formed by diffusion. In this compartment SWCNTs are loaded with protons and acquire positive charges distributed over their surface. Protonation of hydrophobic SWCNTs can also be carried out within the mitochondrial membrane through interaction with the protonated ubiquinone. Such "charge loaded" particles can be transferred as "Sculachev ions" through the inner membrane of the mitochondria due to the potential difference generated by the inner membrane. Physiological consequences of the described mechanism are discussed.

  6. Estimation of Carbon Sink in Surface Carbonate Rocks of Guangxi Province by Using Remote Sensing Images

    Science.gov (United States)

    Jia, B.; Zhou, G.; Wang, H.; Yue, T.; Huang, W.

    2018-04-01

    Studies of the imbalance of source sinks in the carbon cycle show that CO2 absorbed during rock weathering is part of the "miss carbon" of the global carbon cycle. The carbon sink contribution of carbonate rocks obviously plays a very important role in the absorption of atmospheric CO2. Estimation of carbon sinks in karst dynamic system of Guangxi province has great significance for further understanding of global karst carbon cycle and global climate research. This paper quotes the rock data from Tao Xiaodong's paper, which is obtained using RS and GIS techniques. At the same time, the dissolution rate model studied by Zhou Guoqing and others was used to estimate the dissolution rate of carbonate rocks in Guangxi Province. Finally, the CO2 content consumed by carbonate karstification in Guangxi Province was 1342910.447 t a-1. The results obtained are in the same order of magnitude as the CO2 content consumed by carbonate rock karstification in Guangxi Province calculated by Tao Xiaodong.

  7. Temperature dependent mechanical property of PZT film: an investigation by nanoindentation.

    Directory of Open Access Journals (Sweden)

    Yingwei Li

    Full Text Available Load-depth curves of an unpoled Lead Zirconate Titanate (PZT film composite as a function of temperature were measured by nanoindentation technique. Its reduce modulus and hardness were calculated by the typical Oliver-Pharr method. Then the true modulus and hardness of the PZT film were assessed by decoupling the influence of substrate using methods proposed by Zhou et al. and Korsunsky et al., respectively. Results show that the indentation depth and modulus increase, but the hardness decreases at elevated temperature. The increasing of indentation depth and the decreasing of hardness are thought to be caused by the decreasing of the critical stress needed to excite dislocation initiation at high temperature. The increasing of true modulus is attributed to the reducing of recoverable indentation depth induced by back-switched domains. The influence of residual stress on the indentation behavior of PZT film composite was also investigated by measuring its load-depth curves with pre-load strains.

  8. Temperature dependent mechanical property of PZT film: an investigation by nanoindentation.

    Science.gov (United States)

    Li, Yingwei; Feng, Shangming; Wu, Wenping; Li, Faxin

    2015-01-01

    Load-depth curves of an unpoled Lead Zirconate Titanate (PZT) film composite as a function of temperature were measured by nanoindentation technique. Its reduce modulus and hardness were calculated by the typical Oliver-Pharr method. Then the true modulus and hardness of the PZT film were assessed by decoupling the influence of substrate using methods proposed by Zhou et al. and Korsunsky et al., respectively. Results show that the indentation depth and modulus increase, but the hardness decreases at elevated temperature. The increasing of indentation depth and the decreasing of hardness are thought to be caused by the decreasing of the critical stress needed to excite dislocation initiation at high temperature. The increasing of true modulus is attributed to the reducing of recoverable indentation depth induced by back-switched domains. The influence of residual stress on the indentation behavior of PZT film composite was also investigated by measuring its load-depth curves with pre-load strains.

  9. Indepth exploration on history of Qing doctors traveling to Japan.

    Science.gov (United States)

    Guo, X; Saka, S; Okada, K

    1999-04-01

    During the one hundred years and more from the beginning of the 18th century to the beginning of the 19th century, about 16 Chinese doctors, at the invitation of Japanese, went to Japan successively by trade ships to practice medicine and teach Chinese medicine. They also conducted academic exchanges with Japanese doctors. Because both the Japanese authorities of that time and the emperor of Qing dynasty implemented the policy of closing the country, they could only do things in certain areas within limited time. By consulting a vast amount of data and following the footprints of some of the Chinese doctors in Japan, the author has got things into shape about the comings and goings of the doctors who went to Japan during the century and their activities, with the stressed point laid on the achievements of such influential doctors as Zhu Laizhang, Zhu Zizhang, Zhou Qilai, Zhao Songyang, Li Renshan, Hu Zhaoxin and so on.

  10. An Experiment to Study Sporadic Atom Layers in the Earth's Mesosphere and Lower Thermosphere (SAL)

    Science.gov (United States)

    Kelley, Michael C.

    1999-01-01

    The Sudden Atom Layer (SAL) Rocket was successfully launched in February 1998. All instruments worked well except those supplied by NASA Goddard Space Flight Center. (A dummy weight was launched for the neutral mass spectrometer and the ion version died shortly after lift-off.) A paper has already been published in GRL concerning the dust layer detected by an on board instrument and compared to ground-based observations made at the Arecibo Observatory by Cornell graduate student S. Collins (lidar) and Q. Zhou (radar). Collins presented a comparison of the sodium lidar data and onboard observations with a theoretical model by Plane and Cox at the Fan AGU Meeting. In addition Gelinas and Kelley presented a review paper dealing with the entire SAL instrument complement at the same meeting. An unexpected new explanation for the outer scale of E region plasma irregularities has come out of the data set. We anticipate at least a total of four papers will be published within a year of launch.

  11. High-throughput metagenomic technologies for complex microbial community analysis: open and closed formats.

    Science.gov (United States)

    Zhou, Jizhong; He, Zhili; Yang, Yunfeng; Deng, Ye; Tringe, Susannah G; Alvarez-Cohen, Lisa

    2015-01-27

    Understanding the structure, functions, activities and dynamics of microbial communities in natural environments is one of the grand challenges of 21st century science. To address this challenge, over the past decade, numerous technologies have been developed for interrogating microbial communities, of which some are amenable to exploratory work (e.g., high-throughput sequencing and phenotypic screening) and others depend on reference genes or genomes (e.g., phylogenetic and functional gene arrays). Here, we provide a critical review and synthesis of the most commonly applied "open-format" and "closed-format" detection technologies. We discuss their characteristics, advantages, and disadvantages within the context of environmental applications and focus on analysis of complex microbial systems, such as those in soils, in which diversity is high and reference genomes are few. In addition, we discuss crucial issues and considerations associated with applying complementary high-throughput molecular technologies to address important ecological questions. Copyright © 2015 Zhou et al.

  12. L² approaches in several complex variables development of Oka–Cartan theory by L² estimates for the d-bar operator

    CERN Document Server

    Ohsawa, Takeo

    2015-01-01

    The purpose of this monograph is to present the current status of a rapidly developing part of several complex variables, motivated by the applicability of effective results to algebraic geometry and differential geometry. Highlighted are the new precise results on the L² extension of holomorphic functions. In Chapter 1, the classical questions of several complex variables motivating the development of this field are reviewed after necessary preparations from the basic notions of those variables and of complex manifolds such as holomorphic functions, pseudoconvexity, differential forms, and cohomology. In Chapter 2, the L² method of solving the d-bar equation is presented emphasizing its differential geometric aspect. In Chapter 3, a refinement of the Oka–Cartan theory is given by this method. The L² extension theorem with an optimal constant is included, obtained recently by Z. Błocki and by Q.-A. Guan and X.-Y. Zhou separately. In Chapter 4, various results on the Bergman kernel are presented, includi...

  13. Origin of the Luobusa diamond-bearing peridotites from the sub-arc mantle

    Science.gov (United States)

    Liu, Chuanzhou; Zhang, Chang; Wu, Fuyuang; Chung, Sunlin

    2016-04-01

    Ophiolites are the remnants of ancient oceanic lithosphere that were emplaced onto continental margins. Ophiolites along the E-W trending Yarlung-Tsangpo Suture (YTS), which separates the Indian plate from the Eurasian plate, have been regarded as relics of the Neo-Tethys Ocean. The Luobusa ophiolite outcrops at the eastern YTS and mainly consists of harzburgites and dunites that have been intruded by gabbroic/diabase dykes at ca 130 Ma (Zhang et al., 2015). Basaltic lavas are rarely outcropped, and volumetrically minor (C., Liu, C. Z., Wu, F. Y., Zhang, L. L. & Ji, W. Q. Geochemistry and geochronology of maifc rocks from the Luobusa ophiolite, South Tibet. Lithos, 10.1016/j.lithos.2015.1006.1031 (2015). Zhou, M. F., Robinson, P. T., Malpas, J. & Li, Z. J. Podiform chromitites in the Luobusa Ophiolite (Southern Tibet): Implications for melt-rock interaction and chromite segregation in the upper mantle. J. Petrol. 37, 3-21 (1996).

  14. Recovery of nitrogen and phosphorus from alkaline fermentation liquid of waste activated sludge and application of the fermentation liquid to promote biological municipal wastewater treatment.

    Science.gov (United States)

    Tong, Juan; Chen, Yinguang

    2009-07-01

    In previous publications we reported that by controlling the pH at 10.0 the accumulation of short-chain fatty acids (SCFA) during waste activated sludge (WAS) fermentation was remarkably improved [Yuan, H., Chen, Y., Zhang, H., Jiang, S., Zhou, Q., Gu, G., 2006. Improved bioproduction of short-chain fatty acids (SCFAs) from excess sludge under alkaline conditions. Environ. Sci. Technol. 40, 2025-2029], but significant ammonium nitrogen (NH(4)-N) and soluble ortho-phosphorus (SOP) were released [Chen, Y., Jiang, S., Yuan, H., Zhou, Q., Gu, G., 2007. Hydrolysis and acidification of waste activated sludge at different pHs. Water Res. 41, 683-689]. This paper investigated the simultaneous recovery of NH(4)-N and SOP from WAS alkaline fermentation liquid and the application of the fermentation liquid as an additional carbon source for municipal wastewater biological nitrogen and phosphorus removal. The central composite design (CCD) of the response surface methodology (RSM) was employed to optimize and model the simultaneous NH(4)-N and SOP recovery from WAS alkaline fermentation liquid. Under the optimum conditions, the predicted and experimental recovery efficiency was respectively 73.4 and 75.7% with NH(4)-N, and 82.0 and 83.2% with SOP, which suggested that the developed models described the experiments well. After NH(4)-N and SOP recovery, the alkaline fermentation liquid was added to municipal wastewater, and the influence of volume ratio of fermentation liquid to municipal wastewater (FL/MW) on biological nitrogen and phosphorus removal was investigated. The addition of fermentation liquid didn't significantly affect nitrification. Both SOP and total nitrogen (TN) removal were increased with fermentation liquid, but there was no significant increase at FL/MW greater than 1/35. Compared to the blank test, the removal efficiency of SOP and TN at FL/MW=1/35 was improved from 44.0 to 92.9%, and 63.3 to 83.2%, respectively. The enhancement of phosphorus and nitrogen

  15. Real-World Adherence and Persistence to Oral Disease-Modifying Therapies in Multiple Sclerosis Patients Over 1 Year.

    Science.gov (United States)

    Johnson, Kristen M; Zhou, Huanxue; Lin, Feng; Ko, John J; Herrera, Vivian

    2017-08-01

    and injectable/infused DMT use, relapse history, and Charlson Comorbidity Index score. Relative to fingolimod patients, dimethyl fumarate and teriflunomide patients were significantly less likely to have an MPR ≥ 80% (OR = 0.18; 95% CI = 0.09-0.36; P Herrera are employed by Novartis Pharmaceuticals and own Novartis stock. Huanxue Zhou is employed by KMK Consulting, which provides consulting services to Novartis. Study concept and design were contributed by Johnson, Lin, Ko, and Herrera. Zhou collected the data, and data interpretation was performed by Johnson, Lin, Ko, and Herrera. All authors were involved in manuscript revision. The abstract for this study was presented at the AMCP Nexus 2015; October 26-29, 2015; Orlando, Florida.

  16. Dicer maintains the identity and function of proprioceptive sensory neurons.

    Science.gov (United States)

    O'Toole, Sean M; Ferrer, Monica M; Mekonnen, Jennifer; Zhang, Haihan; Shima, Yasuyuki; Ladle, David R; Nelson, Sacha B

    2017-03-01

    Neuronal cell identity is established during development and must be maintained throughout an animal's life (Fishell G, Heintz N. Neuron 80: 602-612, 2013). Transcription factors critical for establishing neuronal identity can be required for maintaining it (Deneris ES, Hobert O. Nat Neurosci 17: 899-907, 2014). Posttranscriptional regulation also plays an important role in neuronal differentiation (Bian S, Sun T. Mol Neurobiol 44: 359-373, 2011), but its role in maintaining cell identity is less established. To better understand how posttranscriptional regulation might contribute to cell identity, we examined the proprioceptive neurons in the dorsal root ganglion (DRG), a highly specialized sensory neuron class, with well-established properties that distinguish them from other neurons in the ganglion. By conditionally ablating Dicer in mice, using parvalbumin (Pvalb)-driven Cre recombinase, we impaired posttranscriptional regulation in the proprioceptive sensory neuron population. Knockout (KO) animals display a progressive form of ataxia at the beginning of the fourth postnatal week that is accompanied by a cell death within the DRG. Before cell loss, expression profiling shows a reduction of proprioceptor specific genes and an increased expression of nonproprioceptive genes normally enriched in other ganglion neurons. Furthermore, although central connections of these neurons are intact, the peripheral connections to the muscle are functionally impaired. Posttranscriptional regulation is therefore necessary to retain the transcriptional identity and support functional specialization of the proprioceptive sensory neurons. NEW & NOTEWORTHY We have demonstrated that selectively impairing Dicer in parvalbumin-positive neurons, which include the proprioceptors, triggers behavioral changes, a lack of muscle connectivity, and a loss of transcriptional identity as observed through RNA sequencing. These results suggest that Dicer and, most likely by extension, micro

  17. Injectable hydrogel as stem cell scaffolds from the thermosensitive terpolymer of NIPAAm/AAc/HEMAPCL

    Directory of Open Access Journals (Sweden)

    Lian S

    2012-09-01

    Full Text Available Sheng Lian,1Yan Xiao,1 Qingqing Bian,1Yu Xia,2 Changfa Guo,2 Shenguo Wang,2 Meidong Lang11Shanghai Key Laboratory of Advanced Polymeric Materials, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, People's Republic of China; 2Department of Cardiac Surgery, Zhongshan Hospital, Fudan University and Shanghai Institute of Cardiovascular Diseases, Shanghai, People's Republic of ChinaAbstract: A series of biodegradable thermosensitive copolymers was synthesized by free radical polymerization with N-isopropylacrylamide (NIPAAm, acrylic acid (AAc and macromer 2-hydroxylethyl methacrylate-poly(ε-caprolactone (HEMAPCL. The structure and composition of the obtained terpolymers were confirmed by proton nuclear magnetic resonance spectroscopy, while their molecular weight was measured using gel permeation chromatography. The copolymers were dissolved in phosphate-buffered saline (PBS solution (pH = 7.4 with different concentrations to prepare hydrogels. The lower critical solution temperature (LCST, cloud point, and rheological property of the hydrogels were determined by differential scanning calorimetry, ultraviolet-visible spectrometry, and rotational rheometry, respectively. It was found that LCST of the hydrogel increased significantly with the increasing NIPAAm content, and hydrogel with higher AAc/HEMAPCL ratio exhibited better storage modulus, water content, and injectability. The hydrogels were formed by maintaining the copolymer solution at 37°C. The degradation experiment on the formed hydrogels was conducted in PBS solution for 2 weeks and demonstrated a less than 20% weight loss. Scanning electron microscopy was also used to study the morphology of the hydrogel. The copolymer with NIPAAm/AAc/HEMAPCL ratio of 88:9.6:2.4 was bioconjugated with type I collagen for the purpose of biocompatibility enhancement. In-vitro cytotoxicity

  18. Sex-Specific Effects of Organophosphate Diazinon on the Gut Microbiome and Its Metabolic Functions.

    Science.gov (United States)

    Gao, Bei; Bian, Xiaoming; Mahbub, Ridwan; Lu, Kun

    2017-02-01

    There is growing recognition of the significance of the gut microbiome to human health, and the association between a perturbed gut microbiome with human diseases has been established. Previous studies also show the role of environmental toxicants in perturbing the gut microbiome and its metabolic functions. The wide agricultural use of diazinon, an organophosphate insecticide, has raised serious environmental health concerns since it is a potent neurotoxicant. With studies demonstrating the presence of a microbiome-gut-brain axis, it is possible that gut microbiome perturbation may also contribute to diazinon toxicity. We investigated the impact of diazinon exposure on the gut microbiome composition and its metabolic functions in C57BL/6 mice. We used a combination of 16S rRNA gene sequencing, metagenomics sequencing, and mass spectrometry-based metabolomics profiling in a mouse model to examine the functional impact of diazinon on the gut microbiome. 16S rRNA gene sequencing revealed that diazinon exposure significantly perturbed the gut microbiome, and metagenomic sequencing found that diazinon exposure altered the functional metagenome. Moreover, metabolomics profiling revealed an altered metabolic profile arising from exposure. Of particular significance, these changes were more pronounced for male mice than for female mice. Diazinon exposure perturbed the gut microbiome community structure, functional metagenome, and associated metabolic profiles in a sex-specific manner. These findings may provide novel insights regarding perturbations of the gut microbiome and its functions as a potential new mechanism contributing to diazinon neurotoxicity and, in particular, its sex-selective effects. Citation: Gao B, Bian X, Mahbub R, Lu K. 2017. Sex-specific effects of organophosphate diazinon on the gut microbiome and its metabolic functions. Environ Health Perspect 125:198-206; http://dx.doi.org/10.1289/EHP202.

  19. Response and recovery measures for two floods in north China during the nineteenth century: a comparative study.

    Science.gov (United States)

    Ye, Yu; Fang, Xiuqi; Li, Fan

    2016-01-01

    The process of human response to natural disasters and its mechanisms as revealed by historical events still has a broad significance for modern society. This study analyzed the disaster relief process and the social response for two floods in China: the Yongding River flood in 1801 and the Yellow River flood in 1841. These two floods reflect the different response processes between the national and provincial capitals during a stage of climate cooling and social transition in the Qing dynasty. Applying methods of historical documents analysis and qualitatively comparative analysis to the materials such as Relief Chronicles Authorized by the Emperor in XinYou and Flood Description in Bian Liang , it shows that: (1) In 1801, the central government took on a lead position, from flood surveying to relief processes. However, local government and gentries played an important role in 1841. (2) In 1801, the government successfully undertook a series of relief measures addressing production, housing, food prices, taxes, and water conservancy and administration. In 1841, the response measures were relatively simple, focusing mainly on providing shelter and food for victims. (3) The government carried out long-term disaster prevention measures such as dredging channels after the flood in 1801. In 1841, however, the efforts were focused mainly on emergency rescue. (4) Refugees in the 1801 flood were effectively managed by a centralized authority. In 1841, regulation of the flooding was delayed by corruption and conflicts between officers, leading to an expansion of the disaster's impact. Above results have led to the conclusion that disaster relief systems and response measures had a significant effect on the consequences of those floods. Various flood relief measures and natural disasters management regimes have implications for contemporary flood hazard mitigation.

  20. Callus induction and plant regeneration by Brazilian new elite wheat genotypes

    Directory of Open Access Journals (Sweden)

    Eliane Cristina Gruszka Vendruscolo

    2008-01-01

    Full Text Available The distinction of genotypes responsive to tissue culture and the development of an efficient regenerationsystem are the first steps towards transgenic plant production. Nine Brazilian wheat (Triticum aestivum L. genotypes werecultivated in vitro to evaluate the embryogenetic capacity. The explants (immature zygotic embryos were tested in twodifferent culture media, MS (Murashige and Skoog 1962 and modified MS - MMS (Zhou et al. 1995 with decreasing dosagesof hormone regulators. Three distinct phases were observed in each medium: induction, maintenance and regeneration. Afterinduction, the somatic embryogenesis of calli was evaluated every 21 days. Genotypes responded differently to the differentculture media. The embryogenic response of genotype CD104 was best in both culture media tested. On MMS, the values ofcallus induction, plant regeneration and ratio of regenerated plantlets per rescued embryo of this genotype were 100%, 99.5%and 1.1%, respectively. Genotypes CD104, CD200126 and CDFAPA 2001129 were most responsive on MS (regenerationcapacity of 37.5%, 33.5% and 33% respectively, and therefore interesting for genetic transformation in plant breedingprograms that develop new elite cultivars with a commercial purpose.

  1. Book Reivew: A chance for lasting survival: Ecology and behavior of wild giant pandas

    Science.gov (United States)

    van Manen, Frank T.

    2015-01-01

    “If we watch species going extinct in front of us, how useful is that we publish 100 or even 1,000 papers by studying them?” (p. 330). This quote from senior author Pan Wenshi captures an important essence of this book. A translation of a 2001 monograph originally published in Chinese, this volume details the findings of a 15-year research program in the Qinling Mountains by Wenshi and his students. Starting in 1984, this Chinese research team from Peking University was only the second to study free-ranging pandas. This is the remarkable journey of a devoted group of field researchers who helped changed the course of giant panda conservation, events that few conservationists outside of China have been aware of until now.Review info: A chance for lasting survival: Ecology and behavior of wild giant pandas. By Pan Wenshi, Lü Zhi, Zhu Xiaojian, Wang Dajun, Wang Hao, Long Yu, Fu Dali, and Zhou Xin; edited by, William J. McShea, Richard B. Harris, David L. Garshelis, and Wang Dajun, 2014. ISBN: 978-1-935623-17-5, 349pp.

  2. How to make thermodynamic perturbation theory to be suitable for low temperature?

    Science.gov (United States)

    Zhou, Shiqi

    2009-02-07

    Low temperature unsuitability is a problem plaguing thermodynamic perturbation theory (TPT) for years. Present investigation indicates that the low temperature predicament can be overcome by employing as reference system a nonhard sphere potential which incorporates one part of the attractive ingredient in a potential function of interest. In combination with a recently proposed TPT [S. Zhou, J. Chem. Phys. 125, 144518 (2006)] based on a lambda expansion (lambda being coupling parameter), the new perturbation strategy is employed to predict for several model potentials. It is shown that the new perturbation strategy can very accurately predict various thermodynamic properties even if the potential range is extremely short and hence the temperature of interest is very low and current theoretical formalisms seriously deteriorate or critically fail to predict even the existence of the critical point. Extensive comparison with existing liquid state theories and available computer simulation data discloses a superiority of the present TPT to two Ornstein-Zernike-type integral equation theories, i.e., hierarchical reference theory and self-consistent Ornstein-Zernike approximation.

  3. Improved hybrid information filtering based on limited time window

    Science.gov (United States)

    Song, Wen-Jun; Guo, Qiang; Liu, Jian-Guo

    2014-12-01

    Adopting the entire collecting information of users, the hybrid information filtering of heat conduction and mass diffusion (HHM) (Zhou et al., 2010) was successfully proposed to solve the apparent diversity-accuracy dilemma. Since the recent behaviors are more effective to capture the users' potential interests, we present an improved hybrid information filtering of adopting the partial recent information. We expand the time window to generate a series of training sets, each of which is treated as known information to predict the future links proven by the testing set. The experimental results on one benchmark dataset Netflix indicate that by only using approximately 31% recent rating records, the accuracy could be improved by an average of 4.22% and the diversity could be improved by 13.74%. In addition, the performance on the dataset MovieLens could be preserved by considering approximately 60% recent records. Furthermore, we find that the improved algorithm is effective to solve the cold-start problem. This work could improve the information filtering performance and shorten the computational time.

  4. Modified homotopy perturbation method for solving hypersingular integral equations of the first kind.

    Science.gov (United States)

    Eshkuvatov, Z K; Zulkarnain, F S; Nik Long, N M A; Muminov, Z

    2016-01-01

    Modified homotopy perturbation method (HPM) was used to solve the hypersingular integral equations (HSIEs) of the first kind on the interval [-1,1] with the assumption that the kernel of the hypersingular integral is constant on the diagonal of the domain. Existence of inverse of hypersingular integral operator leads to the convergence of HPM in certain cases. Modified HPM and its norm convergence are obtained in Hilbert space. Comparisons between modified HPM, standard HPM, Bernstein polynomials approach Mandal and Bhattacharya (Appl Math Comput 190:1707-1716, 2007), Chebyshev expansion method Mahiub et al. (Int J Pure Appl Math 69(3):265-274, 2011) and reproducing kernel Chen and Zhou (Appl Math Lett 24:636-641, 2011) are made by solving five examples. Theoretical and practical examples revealed that the modified HPM dominates the standard HPM and others. Finally, it is found that the modified HPM is exact, if the solution of the problem is a product of weights and polynomial functions. For rational solution the absolute error decreases very fast by increasing the number of collocation points.

  5. Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access: An Editorial Comment for 'The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C' on page 236.

    Science.gov (United States)

    Van Damme, Philip

    2017-10-01

    Loss-of-function mutations in the gene encoding the growth factor progranulin cause degeneration of the ageing brain in a dose-dependent manner. While heterozygous mutations result in adult onset frontotemporal dementia, the much rarer homozygous null mutations cause an early onset lysosomal storage disorder. A better understanding of the biology of progranulin in the central nervous system is needed to find solutions for these incurable diseases. This Editorial highlights a study by Zhou et al. in the current issue of the Journal of Neurochemistry, in which the authors provide data that are a step towards this goal. Progranulin is mainly expressed by neurons and microglia and, although it is a secreted protein, it also ends up in lysosomes. Recently, the trafficking of progranulin and the molecular players involved have become better understood. A special interaction between progranulin and its travelling companion, prosaposin, explains how both proteins can use each other's transport receptors to gain access to lysosomes. © 2017 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of International Society for Neurochemistry.

  6. February 2013 critical care journal club

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2013-02-01

    Full Text Available No abstract available. Article truncated after 150 words. Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO; the OSCILLATE Trial Investigators and the Canadian Critical Care Trials Group. High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome. N Engl J Med. 2013;368:795-805. Young D, Lamb SE, Shah S, Mackenzie I, Tunnicliffe W, Lall R, Rowan K, Cuthbertson BH; the OSCAR Study Group. High-Frequency Oscillation for Acute Respiratory Distress Syndrome. N Engl J Med. 2013;368:806-13. Malhotra A, Drazen JM. High-Frequency Oscillatory Ventilation on Shaky Ground. N Engl J Med. 2013;368:863-5. Two articles and an accompanying editorial, the later co-authored by none less than the editor, appeared in the New England Journal of Medicine this week. These all dealt with the use of high-frequency oscillatory ventilation (HFOV in the adult respiratory distress syndrome (ARDS. As the editorial points …

  7. Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries.

    Science.gov (United States)

    Zhou, Jianye; Jiang, Nan; Wang, Zhenzhen; Li, Longqing; Zhang, Jumei; Ma, Rui; Nie, Hongbing; Li, Zhiqiang

    2017-02-15

    This study aimed to identify the differences in the oral microbial communities in saliva from patients with and without caries by performing sequencing with the Illumina MiSeq platform, as well as to further assess their relationships with environmental factors (salivary pH and iron concentration). Forty-three volunteers were selected, including 21 subjects with and 22 without caries, from one village in Gansu, China. Based on 966,255 trimmed sequences and clustering at the 97% similarity level, 1,303 species-level operational taxonomic units were generated. The sequencing data for the two groups revealed that (i) particular distribution patterns (synergistic effects or competition) existed in the subjects with and without caries at both the genus and species levels and (ii) both the salivary pH and iron concentration had significant influences on the microbial community structure. The significant influences of the oral environment observed in this study increase the current understanding of the salivary microbiome in caries. These results will be useful for expanding research directions and for improving disease diagnosis, prognosis, and therapy. Copyright © 2017 Zhou et al.

  8. Exact Solution of the Six-Vertex Model with Domain Wall Boundary Conditions. Disordered Phase

    CERN Document Server

    Bleher, P M

    2005-01-01

    The six-vertex model, or the square ice model, with domain wall boundary conditions (DWBC) has been introduced and solved for finite $N$ by Korepin and Izergin. The solution is based on the Yang-Baxter equations and it represents the free energy in terms of an $N\\times N$ Hankel determinant. Paul Zinn-Justin observed that the Izergin-Korepin formula can be re-expressed in terms of the partition function of a random matrix model with a nonpolynomial interaction. We use this observation to obtain the large $N$ asymptotics of the six-vertex model with DWBC in the disordered phase. The solution is based on the Riemann-Hilbert approach and the Deift-Zhou nonlinear steepest descent method. As was noticed by Kuperberg, the problem of enumeration of alternating sign matrices (the ASM problem) is a special case of the the six-vertex model. We compare the obtained exact solution of the six-vertex model with known exact results for the 1, 2, and 3 enumerations of ASMs, and also with the exact solution on the so-called f...

  9. On analysis of hydrogeological characteristics and the origin of thermal water in Quan'an basin

    International Nuclear Information System (INIS)

    Tang Shiyao; Wang Lianshe; Jiang Weibing

    2010-01-01

    Thermal water development of Quan'an Basin , in order to understand the hydrogeological characteristics and formation of geothermal water of the basin. This paper in the light of the occurrence of groundwater conditions, physical properties of water and hydraulic characteristics of the Basin, it described the characters of geology and hrydrogeology. According to the circumstances of tectonic movement activities, study on the formation of geothermal water and existing environmental in the west of basin Zhou Di and Nuan Shui Tang area, fracture formed by multi-period tectonic movements and fissures with deep hot water is the main reason for the formation of hot geothermal water. It analyzed the composition of the undergroundwater of the hydrogen, oxygen stable isotopes, escaping gas, water and chemical composition, it came to the conclusion that the relationship between atmospheric precipitation and geothermal water was intimate, the geothermal water supply from atmospheric precipitation. Futhermore, the long-term water dynamics observations results showed that the relationship between atmospheric precipitation and inflow of geothermal water was closed. (authors)

  10. Input-output analysis of CO2 emissions embodied in trade. The effects of spatial aggregation

    International Nuclear Information System (INIS)

    Su, Bin; Ang, B.W.

    2010-01-01

    Energy-related CO 2 emissions embodied in international trade have been widely studied by researchers using the environmental input-output analysis framework. It is well known that both sector aggregation and spatial aggregation affect the results obtained in such studies. With regard to the latter, past studies are often conducted at the national level irrespective of country or economy size. For a large economy with the needed data, studies may be conducted at different levels of spatial aggregation. We examine this problem analytically by extending the work of Su et al. ([Su, B., Huang, H.C., Ang, B.W., Zhou, P., 2010. Input-output analysis of CO 2 emissions embodied in trade: The effects of sector aggregation. Energy Economics 32 (1), 166-175.]) on sector aggregation. We present a numerical example using the data of China and by dividing the country into eight regions. It is found that the results are highly dependent on spatial aggregation. Our study shows that for a large country like China it is meaningful to look into the effect of spatial aggregation. (author)

  11. Realization of a gain with electromagnetically induced transparency system using non-degenerate Zeeman sublevels in 87 Rb

    Science.gov (United States)

    Zhou, Minchuan; Zhou, Zifan; Shahriar, Selim M.

    2017-11-01

    Previously, we had proposed an optically-pumped five-level Gain EIT (GEIT) system, which has a transparency dip superimposed on a gain profile and exhibits a negative dispersion suitable for the white-light-cavity signal-recycling (WLC-SR) scheme of the interferometric gravitational wave detector (Zhou et al., 2015). Using this system as the negative dispersion medium (NDM) in the WLC-SR, we get an enhancement in the quantum noise (QN) limited sensitivity-bandwidth product by a factor of ∼ 18. Here, we show how to realize this GEIT system in a realistic platform, using non-degenerate Zeeman sublevels in cold Rb atoms, employing anomalous dispersion at 795 nm. Using the Caves model for a phase insensitive linear amplifier, we show that an enhancement of the sensitivity-bandwidth product by a factor of ∼ 17 is possible for potentially realizable experimental parameters. While the current LIGO apparatus uses light at 1064 nm, a future embodiment thereof may operate at a wavelength that is consistent with the wavelength considered here.

  12. Quantum neural networks: Current status and prospects for development

    Science.gov (United States)

    Altaisky, M. V.; Kaputkina, N. E.; Krylov, V. A.

    2014-11-01

    The idea of quantum artificial neural networks, first formulated in [34], unites the artificial neural network concept with the quantum computation paradigm. Quantum artificial neural networks were first systematically considered in the PhD thesis by T. Menneer (1998). Based on the works of Menneer and Narayanan [42, 43], Kouda, Matsui, and Nishimura [35, 36], Altaisky [2, 68], Zhou [67], and others, quantum-inspired learning algorithms for neural networks were developed, and are now used in various training programs and computer games [29, 30]. The first practically realizable scaled hardware-implemented model of the quantum artificial neural network is obtained by D-Wave Systems, Inc. [33]. It is a quantum Hopfield network implemented on the basis of superconducting quantum interference devices (SQUIDs). In this work we analyze possibilities and underlying principles of an alternative way to implement quantum neural networks on the basis of quantum dots. A possibility of using quantum neural network algorithms in automated control systems, associative memory devices, and in modeling biological and social networks is examined.

  13. Economic policy uncertainty, equity premium and dependence between their quantiles: Evidence from quantile-on-quantile approach

    Science.gov (United States)

    Raza, Syed Ali; Zaighum, Isma; Shah, Nida

    2018-02-01

    This paper examines the relationship between economic policy uncertainty and equity premium in G7 countries over a period of the monthly data from January 1989 to December 2015 using a novel technique namely QQ regression proposed by Sim and Zhou (2015). Based on QQ approach, we estimate how the quantiles of the economic policy uncertainty affect the quantiles of the equity premium. Thus, it provides a comprehensive insight into the overall dependence structure between the equity premium and economic policy uncertainty as compared to traditional techniques like OLS or quantile regression. Overall, our empirical evidence suggests the existence of a negative association between equity premium and EPU predominately in all G7 countries, especially in the extreme low and extreme high tails. However, differences exist among countries and across different quantiles of EPU and the equity premium within each country. The existence of this heterogeneity among countries is due to the differences in terms of dependency on economic policy, other stock markets, and the linkages with other country's equity market.

  14. Control of heteroepitaxial stacking by substrate miscut

    International Nuclear Information System (INIS)

    Bonham, S.W.; Flynn, C.P.

    1998-01-01

    We report studies of fcc epitaxial crystals, grown on Nb(110), in which the Nb surface offers a template for selection between the two alternative stackings, ABCA hor-ellipsis and ACBA hor-ellipsis of the fcc close-packed planes. The Nb templates were grown epitaxially about 500 Angstrom thick on sapphire (11 bar 20), and the fcc material studied was Cu 3 Au. From symmetry it is not possible for the perfect bcc (110) surface to cause any such selection, which is here attributed instead to vicinal miscut: the logarithm of the stacking ratio must be even in miscut along [001] and odd in miscut along [1 bar 10]. We find that the measured selectivity is small for miscuts less than about 0.5 degree, but approaches a factor 10 3 for miscuts along [1 bar 10] greater than about 1 degree. A mechanism for the selection process is discussed in terms of fingered mesostructures that grow on Nb(110) in this regime, as observed first by Zhou, Bonham, and Flynn. copyright 1998 The American Physical Society

  15. Effects of Arthro-7® in relieving symptoms of osteoarthritis with mild to moderate arthralgia [Corrigendum

    Directory of Open Access Journals (Sweden)

    Xie Q

    2013-05-01

    Full Text Available  Xie Q, Zhou T, Yen L, Shariff M, Nguyen T, Kami K, Gu P, Liang L, Rao J, Shi R. Nutrition and Dietary Supplements. 2013;5:1–6.On page 2, under the Materials section, the 1st paragraph should read "The Arthro-7 and placebo capsules were provided by Robinson Pharma (Orange County, CA, USA. The Arthro-7 was in the form of capsules containing vitamin C, collagen (from chicken cetyl myristoleate (CMO, lipase, methylsulfonylmethane (MSM, curcumin, and bromelain (Table 1. The main ingredient of the placebo capsule was corn powder. In addition, there were gelatin, glycerin, purified water and titanium dioxide, and artificial food coloring."On page 4, under the Discussion section, 2nd paragraph, the 2nd and 3rd sentences should read "Collagen is the main component of articular cartilage and the principal substance responsible for maintaining the physical, chemical, and mechanical properties of articular cartilage. The collagen in Arthro-7 is extracted from chicken, which has previously been shown to suppress collagen-induced arthritis.18"Read the original article  

  16. The clinical application of linagliptin in Asians

    Directory of Open Access Journals (Sweden)

    Cao CQ

    2015-09-01

    Full Text Available Chu-qing Cao, Yu-fei Xiang, Zhi-guang Zhou Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Institute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China Abstract: Asia has a growing diabetic population. Linagliptin, a member of dipeptidyl peptidase-4 inhibitor class, is unique in its nonlinear pharmacokinetics with the characteristics of rapid attainment of steady state, little accumulation, predominantly nonrenal route of elimination, prolonged terminal half-life, and sustained inhibition of dipeptidyl peptidase-4 enzyme. No clinically relevant difference in pharmacokinetics was observed between Asians and non-Asians. The management of type 2 diabetes is increasingly challenging with the progression of disease, especially with the requirements of minimal hypoglycemia, weight gain, fluid retention, and other adverse effects. Linagliptin was efficacious and well-tolerated in Asian type 2 diabetes patients with or without renal or hepatic dysfunctions, comparable to that in Caucasians. This review will focus on the usage of linagliptin in clinical studies in Asians. Keywords: linagliptin, Asians, type 2 diabetes

  17. Coding the presence of visual objects in a recurrent neural network of visual cortex.

    Science.gov (United States)

    Zwickel, Timm; Wachtler, Thomas; Eckhorn, Reinhard

    2007-01-01

    Before we can recognize a visual object, our visual system has to segregate it from its background. This requires a fast mechanism for establishing the presence and location of objects independently of their identity. Recently, border-ownership neurons were recorded in monkey visual cortex which might be involved in this task [Zhou, H., Friedmann, H., von der Heydt, R., 2000. Coding of border ownership in monkey visual cortex. J. Neurosci. 20 (17), 6594-6611]. In order to explain the basic mechanisms required for fast coding of object presence, we have developed a neural network model of visual cortex consisting of three stages. Feed-forward and lateral connections support coding of Gestalt properties, including similarity, good continuation, and convexity. Neurons of the highest area respond to the presence of an object and encode its position, invariant of its form. Feedback connections to the lowest area facilitate orientation detectors activated by contours belonging to potential objects, and thus generate the experimentally observed border-ownership property. This feedback control acts fast and significantly improves the figure-ground segregation required for the consecutive task of object recognition.

  18. A review: Development of a microdose model for analysis of adaptive response and bystander dose response behavior.

    Science.gov (United States)

    Leonard, Bobby E

    2008-02-27

    Prior work has provided incremental phases to a microdosimetry modeling program to describe the dose response behavior of the radio-protective adaptive response effect. We have here consolidated these prior works (Leonard 2000, 2005, 2007a, 2007b, 2007c) to provide a composite, comprehensive Microdose Model that is also herein modified to include the bystander effect. The nomenclature for the model is also standardized for the benefit of the experimental cellular radio-biologist. It extends the prior work to explicitly encompass separately the analysis of experimental data that is 1.) only dose dependent and reflecting only adaptive response radio-protection, 2.) both dose and dose-rate dependent data and reflecting only adaptive response radio-protection for spontaneous and challenge dose damage, 3.) only dose dependent data and reflecting both bystander deleterious damage and adaptive response radio-protection (AR-BE model). The Appendix cites the various applications of the model. Here we have used the Microdose Model to analyze the, much more human risk significant, Elmore et al (2006) data for the dose and dose rate influence on the adaptive response radio-protective behavior of HeLa x Skin cells for naturally occurring, spontaneous chromosome damage from a Brachytherapy type (125)I photon radiation source. We have also applied the AR-BE Microdose Model to the Chromosome inversion data of Hooker et al (2004) reflecting both low LET bystander and adaptive response effects. The micro-beam facility data of Miller et al (1999), Nagasawa and Little (1999) and Zhou et al (2003) is also examined. For the Zhou et al (2003) data, we use the AR-BE model to estimate the threshold for adaptive response reduction of the bystander effect. The mammogram and diagnostic X-ray induction of AR and protective BE are observed. We show that bystander damage is reduced in the similar manner as spontaneous and challenge dose damage as shown by the Azzam et al (1996) data. We cite

  19. Vegetation, soil property and climatic controls over greenhouse gas fluxes in a blanket peatland hosting a wind farm

    Science.gov (United States)

    Armstrong, Alona; Waldron, Susan; Ostle, Nick; Whitaker, Jeanette

    2013-04-01

    Peatlands are important carbon (C) stores, with boreal and subarctic peatlands containing 15-30 % of the world soil carbon stock (Limpens et al., 2008). Research has demonstrated that greenhouse gas (GHG) fluxes in peatlands are influenced by vegetation, soil property and climatic variables, including plant functional type (PFT), water table height and temperature. In this paper we present data from Black Law Wind Farm, Scotland, where we examined the effect of a predicted wind turbine-induced microclimatic gradient and PFT on carbon dioxide (CO2) and methane (CH4) fluxes. Moreover, we determined the role of vegetation, soil property and climatic variables as predictors of the variation in CO2 and CH4 emissions. We measured CO2 and CH4 at 48 plots within Black Law Wind Farm at monthly intervals from May 2011 to April 2012. Four sampling sites were located along a predicted wind turbine-induced microclimatic gradient. At each site four blocks were established, each with plots in areas dominated by mosses, sedges and shrubs. Plant biomass and PFT (vegetation factors); soil moisture, water table height, peat depth, C content, nitrogen (N) content and C:N (soil properties); and soil temperature and photosynthetically active radiation (PAR) (climatic variables) were measured. Analysis of variance (ANOVA) models based on the microclimatic gradient site, PFT and season when measurements were made explained 58 %, 44 % and 49 % of the variation in ecosystem respiration, photosynthesis and CH4, respectively. Site, PFT, season and their interactions were all significant for respiration and photosynthesis (with the exception of the PFT*site interaction) but for CH4 only the main effects were significant. Parsimonious ANOVA models using the biotic, soil property and climatic explanatory data explained 62 %, 55 % and 49 % of the variation in respiration, photosynthesis and CH4, respectively. Published studies (Baidya Roy and Traiteur 2010; Zhou et al., 2012) and preliminary

  20. Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Zhang Y

    2015-05-01

    Full Text Available Yan Zhang,1,2,* Sainan Li,1,* Lei He,1 Fan Wang,1 Kan Chen,1 Jingjing Li,1 Tong Liu,1 Yuanyuan Zheng,1 Jianrong Wang,1,3 Wenxia Lu,1,3 Yuqing Zhou,1,4 Qin Yin,1,4 Yujing Xia,1 Yingqun Zhou,1 Jie Lu,1 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 3The First Clinical Medical College of Nanjing Medical University, Nanjing, 4The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China *These authors contributed equally to this work Background: Although the effectiveness of treatment with ursodeoxycholic acid (UDCA and fenofibrate for primary biliary cirrhosis (PBC has been suggested by small trials, a systematic review to summarize the evidence has not yet been carried out.Methods: A meta-analysis of all long-term randomized controlled trials comparing the combination of UDCA and fenofibrate with UDCA monotherapy was performed via electronic searches.Results: Six trials, which included 84 patients, were assessed. Combination therapy with UDCA and fenofibrate was more effective than UDCA monotherapy in improving alkaline phosphatase (mean difference [MD]: -90.44 IU/L; 95% confidence interval [CI]: -119.95 to -60.92; P<0.00001, gamma-glutamyl transferase (MD: -61.58 IU/L; 95% CI: -122.80 to -0.35; P=0.05, immunoglobulin M (MD: -38.45 mg/dL; 95% CI: -64.38 to -12.51; P=0.004, and triglycerides (MD: -0.41 mg/dL; 95% CI: -0.82 to -0.01; P=0.05. However, their effects on pruritus (odds ratio [OR]: 0.39; 95% CI: 0.09–1.78; P=0.23, total bilirubin (MD: -0.05 mg/dL; 95% CI: -0.21 to 0.12; P=0.58, and alanine aminotransferase (MD: -3.31 IU/L; 95% CI: -14.60 to 7.97; P=0.56 did not differ significantly. This meta-analysis revealed no significant differences in the incidence of adverse events (OR: 0.21; 95% CI: 0.03–1.25; P=0.09 between patients treated with

  1. Optimized multiparametric flow cytometric analysis of circulating endothelial cells and their subpopulations in peripheral blood of patients with solid tumors: a technical analysis

    Directory of Open Access Journals (Sweden)

    Zhou F

    2018-03-01

    Full Text Available Fangbin Zhou,1,2 Yaying Zhou,3 Ming Yang,1 Jinli Wen,3 Jun Dong,4 Wenyong Tan1 1Department of Oncology, The Second Clinical Medical College, Shenzhen People’s Hospital, Jinan University, Shenzhen, People’s Republic of China; 2Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, People’s Republic of China; 3Clinical Medical Research Center, The Second Clinical Medical College, Shenzhen People’s Hospital, Jinan University, Shenzhen, People’s Republic of China; 4Department of Pathophysiology, Key Laboratory of the State Administration of Traditional Chinese Medicine, Medical College of Jinan University, Guangzhou, People’s Republic of China Background: Circulating endothelial cells (CECs and their subpopulations could be potential novel biomarkers for various malignancies. However, reliable enumerable methods are warranted to further improve their clinical utility. This study aimed to optimize a flow cytometric method (FCM assay for CECs and subpopulations in peripheral blood for patients with solid cancers.Patients and methods: An FCM assay was used to detect and identify CECs. A panel of 60 blood samples, including 44 metastatic cancer patients and 16 healthy controls, were used in this study. Some key issues of CEC enumeration, including sample material and anticoagulant selection, optimal titration of antibodies, lysis/wash procedures of blood sample preparation, conditions of sample storage, sufficient cell events to enhance the signal, fluorescence-minus-one controls instead of isotype controls to reduce background noise, optimal selection of cell surface markers, and evaluating the reproducibility of our method, were integrated and investigated. Wilcoxon and Mann–Whitney U tests were used to determine statistically significant differences.Results: In this validation study, we refined a five-color FCM method to detect CECs and their subpopulations in peripheral blood of patients

  2. A meta-analytic review of the association between two common SNPs in miRNAs and lung cancer susceptibility

    Directory of Open Access Journals (Sweden)

    Xiao S

    2018-04-01

    Full Text Available Sha Xiao,1 Songzan Sun,1 Wenfang Long,1 Shicheng Kuang,2 Yunru Liu,1 Hairong Huang,1 Jing Zhou,1 Yongjiang Zhou,1 Xiaobo Lu3 1Department of Environmental and Occupational Health, School of Public Health, Hainan Medical University, Haikou, People’s Republic of China; 2Department of Pharmacy, Hainan General Hospital, Haikou, People’s Republic of China; 3Department of Toxicology, School of Public Health, China Medical University, Shenyang, People’s Republic of China Background: MicroRNAs (miRNAs are involved in many biological processes, including tumor suppression. Multiple studies have shown an association between the miRNA-196a2 rs11614913 and miRNA-146a rs2910164 polymorphisms and cancer risk. However, the implications of the reported data are debatable and inconclusive.Materials and methods: Relevant articles were retrieved from the PubMed, EMBASE, China National Knowledge Infrastructure, and WanFang databases from January 1, 2007, to April 30, 2017. Studies were assessed based on designated inclusion and exclusion criteria, and data were manually extracted from relevant studies by two investigators. Pooled odds ratios (ORs and 95% confidence intervals (CIs were calculated to explore the association between two single-nucleotide polymorphisms (SNPs in miRNAs and lung cancer susceptibility.Results: Nine eligible articles were included, consisting of 3,101 cancer cases and 3,234 controls for miRNA-196a2 rs11614913, and 3,483 cases and 3,578 controls for miRNA-146a rs2910164. For studies evaluating miRNA-196a2 rs11614913, significant associations with lung cancer risk were discovered. Overall, the pooled analysis showed that miRNA-196a2 rs11614913 was associated with a decreased cancer risk (CC vs TT: OR = 1.25, 95% CI: 1.09–1.44; CT vs TT: OR = 1.26, 95% CI: 1.03–1.53. For miRNA-146a rs2910164, only the CC genotype was found to be associated with high lung cancer risk (OR = 1.30, 95% CI: 1.13–1.49. Subgroup analyses based on

  3. The association between methylated CDKN2A and cervical carcinogenesis, and its diagnostic value in cervical cancer: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Li J

    2016-08-01

    Full Text Available Jinyun Li,1,2,* Chongchang Zhou,1,* Haojie Zhou,3,* Tianlian Bao,1 Tengjiao Gao,1 Xiangling Jiang,1 Meng Ye1,2 1Department of Biochemistry and Molecular Biology, School of Medicine, Ningbo University, 2Department of Medical Oncology, Affiliated Hospital, Ningbo University, 3Department of Molecular Diagnosis, Ningbo Diagnostic Pathology Center, Ningbo, Zhejiang, People’s Republic of China *These authors are co-first authors of this work Background: Cervical cancer is the second deadliest gynecologic malignancy, characterized by apparently precancerous lesions and cervical intraepithelial neoplasia (CIN, and having a long course from the development of CIN to cervical cancer. Cyclin-dependent kinase inhibitor 2A (CDKN2A is a well-documented tumor suppressor gene and is commonly methylated in cervical cancer. However, the relationship between methylated CDKN2A and carcinogenesis in cervical cancer is inconsistent, and the diagnostic accuracy of methylated CDKN2A is underinvestigated. In this study, we attempted to quantify the association between CDKN2A methylation and the carcinogenesis of cervical cancer, and its diagnostic power.Methods: We systematically reviewed four electronic databases and identified 26 studies involving 1,490 cervical cancers, 1,291 CINs, and 964 controls. A pooled odds ratio (OR with corresponding 95% confidence intervals (95% CI was calculated to evaluate the association between methylated CDKN2A and the carcinogenesis of cervical cancer. Specificity, sensitivity, the area under the receiver operating characteristic curve, and the diagnostic odds ratio were computed to assess the effect of methylated CDKN2A in the diagnosis of cervical cancer.Results: Our results indicated an upward trend in the methylation frequency of CDKN2A in the carcinogenesis of cervical cancer (cancer vs control: OR =23.67, 95% CI =15.54–36.06; cancer vs CIN: OR =2.53, 95% CI =1.79–3.5; CIN vs control: OR =9.68, 95% CI =5.82–16.02. The

  4. A Generalizable Methodology for Quantifying User Satisfaction

    Science.gov (United States)

    Huang, Te-Yuan; Chen, Kuan-Ta; Huang, Polly; Lei, Chin-Laung

    Quantifying user satisfaction is essential, because the results can help service providers deliver better services. In this work, we propose a generalizable methodology, based on survival analysis, to quantify user satisfaction in terms of session times, i. e., the length of time users stay with an application. Unlike subjective human surveys, our methodology is based solely on passive measurement, which is more cost-efficient and better able to capture subconscious reactions. Furthermore, by using session times, rather than a specific performance indicator, such as the level of distortion of voice signals, the effects of other factors like loudness and sidetone, can also be captured by the developed models. Like survival analysis, our methodology is characterized by low complexity and a simple model-developing process. The feasibility of our methodology is demonstrated through case studies of ShenZhou Online, a commercial MMORPG in Taiwan, and the most prevalent VoIP application in the world, namely Skype. Through the model development process, we can also identify the most significant performance factors and their impacts on user satisfaction and discuss how they can be exploited to improve user experience and optimize resource allocation.

  5. Hyperosmolar nonketotic hyperglycemic coma induced by methylprednisolone pulse therapy for acute rejection after liver transplantation: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Zhou J

    2014-12-01

    Full Text Available Jian Zhou,* Weiqiang Ju,* Xiaopeng Yuan, Xiaofeng Zhu, Dongping Wang, Xiaoshun HeOrgan Transplant Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China *These authors contributed equally to this work Abstract: Hyperosmolar nonketotic hyperglycemic coma (HNKHC is a serious, rare complication induced by methylprednisolone (MP pulse therapy for acute rejection after orthotopic liver transplantation (OLT. Herein, we report an unusual case of a 58-year-old woman who experienced acute rejection at 30 months after OLT, only one case in which HNKHC resulted in MP pulse therapy for acute rejection in all 913 recipients in our center. The general morbidity of HNKHC was 1.09‰ in this study. HNKHC is characterized by rapid onset, rapid progression, and a lack of specific clinical manifestations. High-dose MP management was a clear risk factor. The principle of treatment included rapid rehydration, low-dose insulin infusion, and correcting disorders of electrolytes and acidosis. In conclusion, clinicians considering MP pulse therapy after OLT should be alert to the occurrence of HNKHC. Keywords: liver transplantation, complications, hyperosmolar nonketotic hyperglycemic coma, methylprednisolone pulse therapy, principle of treatment

  6. Universality Conjecture and Results for a Model of Several Coupled Positive-Definite Matrices

    Science.gov (United States)

    Bertola, Marco; Bothner, Thomas

    2015-08-01

    The paper contains two main parts: in the first part, we analyze the general case of matrices coupled in a chain subject to Cauchy interaction. Similarly to the Itzykson-Zuber interaction model, the eigenvalues of the Cauchy chain form a multi level determinantal point process. We first compute all correlations functions in terms of Cauchy biorthogonal polynomials and locate them as specific entries of a matrix valued solution of a Riemann-Hilbert problem. In the second part, we fix the external potentials as classical Laguerre weights. We then derive strong asymptotics for the Cauchy biorthogonal polynomials when the support of the equilibrium measures contains the origin. As a result, we obtain a new family of universality classes for multi-level random determinantal point fields, which include the Bessel universality for 1-level and the Meijer-G universality for 2-level. Our analysis uses the Deift-Zhou nonlinear steepest descent method and the explicit construction of a origin parametrix in terms of Meijer G-functions. The solution of the full Riemann-Hilbert problem is derived rigorously only for p = 3 but the general framework of the proof can be extended to the Cauchy chain of arbitrary length p.

  7. Effects of Particles Collision on Separating Gas–Particle Two-Phase Turbulent Flows

    KAUST Repository

    Sihao, L. V.

    2013-10-10

    A second-order moment two-phase turbulence model incorporating a particle temperature model based on the kinetic theory of granular flow is applied to investigate the effects of particles collision on separating gas–particle two-phase turbulent flows. In this model, the anisotropy of gas and solid phase two-phase Reynolds stresses and their correlation of velocity fluctuation are fully considered using a presented Reynolds stress model and the transport equation of two-phase stress correlation. Experimental measurements (Xu and Zhou in ASME-FED Summer Meeting, San Francisco, Paper FEDSM99-7909, 1999) are used to validate this model, source codes and prediction results. It showed that the particles collision leads to decrease in the intensity of gas and particle vortices and takes a larger effect on particle turbulent fluctuations. The time-averaged velocity, the fluctuation velocity of gas and particle phase considering particles colli-sion are in good agreement with experimental measurements. Particle kinetic energy is always smaller than gas phase due to energy dissipation from particle collision. Moreover, axial– axial and radial–radial fluctuation velocity correlations have stronger anisotropic behaviors. © King Fahd University of Petroleum and Minerals 2013

  8. Determining decoupling points in a supply chain networks using NSGA II algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Ebrahimiarjestan, M.; Wang, G.

    2017-07-01

    Purpose: In the model, we used the concepts of Lee and Amaral (2002) and Tang and Zhou (2009) and offer a multi-criteria decision-making model that identify the decoupling points to aim to minimize production costs, minimize the product delivery time to customer and maximize their satisfaction. Design/methodology/approach: We encounter with a triple-objective model that meta-heuristic method (NSGA II) is used to solve the model and to identify the Pareto optimal points. The max (min) method was used. Findings: Our results of using NSGA II to find Pareto optimal solutions demonstrate good performance of NSGA II to extract Pareto solutions in proposed model that considers determining of decoupling point in a supply network. Originality/value: So far, several approaches to model the future have been proposed, of course, each of them modeled a part of this concept. This concept has been considered more general in the model that defined in follow. In this model, we face with a multi-criteria decision problem that includes minimization of the production costs and product delivery time to customers as well as customer consistency maximization.

  9. Concise quantum associative memories with nonlinear search algorithm

    International Nuclear Information System (INIS)

    Tchapet Njafa, J.P.; Nana Engo, S.G.

    2016-01-01

    The model of Quantum Associative Memories (QAM) we propose here consists in simplifying and generalizing that of Rigui Zhou et al. [1] which uses the quantum matrix with the binary decision diagram put forth by David Rosenbaum [2] and the Abrams and Lloyd's nonlinear search algorithm [3]. Our model gives the possibility to retrieve one of the sought states in multi-values retrieving scheme when a measurement is done on the first register in O(c-r) time complexity. It is better than Grover's algorithm and its modified form which need O(√((2 n )/(m))) steps when they are used as the retrieval algorithm. n is the number of qubits of the first register and m the number of x values for which f(x) = 1. As the nonlinearity makes the system highly susceptible to the noise, an analysis of the influence of the single qubit noise channels on the Nonlinear Search Algorithm of our model of QAM shows a fidelity of about 0.7 whatever the number of qubits existing in the first register, thus demonstrating the robustness of our model. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  10. Investigation of Current Situation of Learning Motivation, Social Anxiety and Loneliness of the Left-behind Children in Rural Primary School

    Directory of Open Access Journals (Sweden)

    Zhang Biyun

    2015-01-01

    Full Text Available Objective: To understand the situation of learning motivation, social anxiety and loneliness of the left-behind children. Method: Selecting three rural primary schools in Xian’an District of Xianning City to investigate left-behind situation, learning motivation, social anxiety and loneliness of pupils in Grades 4 to 6 in rural primary school in Xian’an District by the use of the MAAT-I-A which is revised by Zhou Bucheng, the Social Anxiety Scale for Children (SASC and the Children’s Loneliness Scale (CLS. Results: (1 The learning motivation of the left-behind children in rural primary school is in a slightly higher medium level. Social anxiety is significantly higher than normal level in Chinese city, and the level of loneliness of about 1/5 of the left-behind children is relatively high. (2 The score of learning motivation, social anxiety and loneliness of the left-behind children in the level of knowledge learning has significant grade differences, without significant gender differences. (3 The level of learning motivation, social anxiety and loneliness of the left-behind children is slightly higher than that of non-left-behind children, but both differences are not significant.

  11. A new laryngeal mask supraglottic airway device with integrated balloon line: a descriptive and comparative bench study

    Directory of Open Access Journals (Sweden)

    Zhou YH

    2016-11-01

    Full Text Available YingHai Zhou,1 Korinne Jew2 1Research & Development, Patient Monitoring & Recovery, Medtronic Technology Center, Shanghai, People’s Republic of China; 2Medical Affairs, Minimally Invasive Therapies Group, Medtronic, Boulder, CO, USA Abstract: Laryngeal masks are invasive devices for airway management placed in the supraglottic position. The Shiley™ laryngeal mask (Shiley™ LM features an integrated inflation tube and airway shaft to facilitate product insertion and reduce the chance of tube occlusion when patients bite down. This study compared the Shiley LM to two other disposable laryngeal mask devices, the Ambu® AuraStraight™ and the LMA Unique™. Overall device design, tensile strength, flexibility of various structures, and sealing performance were measured. The Shiley LM is structurally stronger and its shaft is more resistant to compression than the other devices. The Shiley LM is generally less flexible than the other devices, but this relationship varies with device size. Sealing performance of the devices was similar in a bench assay. The results of this bench study demonstrate that the new Shiley LM resembles other commercially available laryngeal mask devices, though it exhibits greater tensile strength and lower flexibility. Keywords: laryngeal mask, supraglottic airway, supralaryngeal device

  12. Parallel Monte Carlo simulation of aerosol dynamics

    KAUST Repository

    Zhou, K.

    2014-01-01

    A highly efficient Monte Carlo (MC) algorithm is developed for the numerical simulation of aerosol dynamics, that is, nucleation, surface growth, and coagulation. Nucleation and surface growth are handled with deterministic means, while coagulation is simulated with a stochastic method (Marcus-Lushnikov stochastic process). Operator splitting techniques are used to synthesize the deterministic and stochastic parts in the algorithm. The algorithm is parallelized using the Message Passing Interface (MPI). The parallel computing efficiency is investigated through numerical examples. Near 60% parallel efficiency is achieved for the maximum testing case with 3.7 million MC particles running on 93 parallel computing nodes. The algorithm is verified through simulating various testing cases and comparing the simulation results with available analytical and/or other numerical solutions. Generally, it is found that only small number (hundreds or thousands) of MC particles is necessary to accurately predict the aerosol particle number density, volume fraction, and so forth, that is, low order moments of the Particle Size Distribution (PSD) function. Accurately predicting the high order moments of the PSD needs to dramatically increase the number of MC particles. 2014 Kun Zhou et al.

  13. 高效蓄热式钢包烘烤技术在杭钢电炉的应用

    Institute of Scientific and Technical Information of China (English)

    战建军; 尹涛

    2014-01-01

    介绍了杭钢电炉公司100吨钢包加热烘烤器在使用中发生的一些问题同时也介绍了改造后蓄热式钢包烘烤器使用的情况。实践证明在节能、环保、经济效益等方面取得了较好的效果;并对烧嘴砖的使用寿命偏短、烘烤包盖处逸气量大等存在的问题进行了分析。%s The using of Hang Zhou Iron and Steel Group Company original 100 tons ladle baking equipment is analyzed, and the application effect of new 100 tons ladle baking equipment of the regenerative heat is discussed in detail. Energy-saving, reducing harmful emissions and economic benefit of the new ladle baking equipment were analyzed. Some problems, such as short life of burner brick,large amount leakage of clad cover, and so on,are discussed.

  14. Determining decoupling points in a supply chain networks using NSGA II algorithm

    International Nuclear Information System (INIS)

    Ebrahimiarjestan, M.; Wang, G.

    2017-01-01

    Purpose: In the model, we used the concepts of Lee and Amaral (2002) and Tang and Zhou (2009) and offer a multi-criteria decision-making model that identify the decoupling points to aim to minimize production costs, minimize the product delivery time to customer and maximize their satisfaction. Design/methodology/approach: We encounter with a triple-objective model that meta-heuristic method (NSGA II) is used to solve the model and to identify the Pareto optimal points. The max (min) method was used. Findings: Our results of using NSGA II to find Pareto optimal solutions demonstrate good performance of NSGA II to extract Pareto solutions in proposed model that considers determining of decoupling point in a supply network. Originality/value: So far, several approaches to model the future have been proposed, of course, each of them modeled a part of this concept. This concept has been considered more general in the model that defined in follow. In this model, we face with a multi-criteria decision problem that includes minimization of the production costs and product delivery time to customers as well as customer consistency maximization.

  15. Analysis of nonlocal phonon thermal conductivity simulations showing the ballistic to diffusive crossover

    Science.gov (United States)

    Allen, Philip B.

    2018-04-01

    Simulations [e.g., X. W. Zhou et al., Phys. Rev. B 79, 115201 (2009), 10.1103/PhysRevB.79.115201] show nonlocal effects of the ballistic/diffusive crossover. The local temperature has nonlinear spatial variation not contained in the local Fourier law j ⃗(r ⃗) =-κ ∇ ⃗T (r ⃗) . The heat current j ⃗(r ⃗) depends not just on the local temperature gradient ∇ ⃗T (r ⃗) but also on temperatures at points r⃗' within phonon mean free paths, which can be micrometers long. This paper uses the Peierls-Boltzmann transport theory in nonlocal form to analyze the spatial variation Δ T (r ⃗) . The relaxation-time approximation (RTA) is used because the full solution is very challenging. Improved methods of extrapolation to obtain the bulk thermal conductivity κ are proposed. Callaway invented an approximate method of correcting RTA for the q ⃗ (phonon wave vector or crystal momentum) conservation of N (Normal as opposed to Umklapp) anharmonic collisions. This method is generalized to the nonlocal case where κ (k ⃗) depends on the wave vector of the current j ⃗(k ⃗) and temperature gradient i k ⃗Δ T (k ⃗) .

  16. Eulerian-Lagranigan simulation of aerosol evolution in turbulent mixing layer

    KAUST Repository

    Zhou, Kun

    2016-09-23

    The formation and evolution of aerosol in turbulent flows are ubiquitous in both industrial processes and nature. The intricate interaction of turbulent mixing and aerosol evolution in a canonical turbulent mixing layer was investigated by a direct numerical simulation (DNS) in a recent study (Zhou, K., Attili, A., Alshaarawi, A., and Bisetti, F. Simulation of aerosol nucleation and growth in a turbulent mixing layer. Physics of Fluids, 26, 065106 (2014)). In this work, Monte Carlo (MC) simulation of aerosol evolution is carried out along Lagrangian trajectories obtained in the previous simulation, in order to quantify the error of the moment method used in the previous simulation. Moreover, the particle size distribution (PSD), not available in the previous works, is also investigated. Along a fluid parcel moving through the turbulent flow, temperature and vapor concentration exhibit complex fluctuations, triggering complicate aerosol processes and rendering complex PSD. However, the mean PSD is found to be bi-modal in most of the mixing layer except that a tri-modal distribution is found in the turbulent transition region. The simulated PSDs agree with the experiment observations available in the literature. A different explanation on the formation of such PSDs is provided.

  17. Late Pliocene diversity and distribution of Drynaria (Polypodiaceae in western Yunnan explained by forest vegetation and humid climates

    Directory of Open Access Journals (Sweden)

    Yong-Jiang Huang

    2016-08-01

    Full Text Available The palaeodiversity of flowering plants in Yunnan has been extensively interpreted from both a molecular and fossil perspective. However, for cryptogamic plants such as ferns, the palaeodiversity remains poorly known. In this study, we describe a new ferny fossil taxon, Drynaria lanpingensis sp. nov. Huang, Su et Zhou (Polypodiaceae, from the late Pliocene of northwestern Yunnan based on fragmentary frond and pinna with in situ spores. The frond is pinnatifid and the pinnae are entirely margined. The sori are arranged in one row on each side of the primary vein. The spores have a semicircular to bean-shaped equatorial view and a tuberculate surface. Taken together with previously described fossils, there are now representatives of three known fossil taxa of Drynaria from the late Pliocene of western Yunnan. These finds suggest that Drynaria diversity was considerable in the region at that time. As Drynaria is a shade-tolerant plant, growing preferably in wet conditions in the understory of forests, its extensive existence may indicate forest vegetation and humid climates in western Yunnan during the late Pliocene. This is in line with results from floristic investigations and palaeoclimatic reconstructions based on fossil floras.

  18. Preparation of FeO(OH Modified with Polyethylene Glycol and Its Catalytic Activity on the Reduction of Nitrobenzene with Hydrazine Hydrate

    Directory of Open Access Journals (Sweden)

    Ke Ying Cai

    2016-10-01

    Full Text Available Iron oxyhydroxide was prepared by dropping ammonia water to Fe(NO33.9H2O dispersed in polyethylene glycol (PEG 1000. The catalyst was characterized by X-ray powder diffraction, Fourier transform infrared spectroscopy and laser particle size analyzer. The results showed the catalyst modified with polyethylene glycol was amorphous. The addition of PEG during the preparation make the particle size of the catalyst was smaller and more uniform. The catalytic performance was tested in the reduction of nitroarenes to corresponding amines with hydrazine hydrate, and the catalyst showed excellent activity and stability. Copyright © 2016 BCREC GROUP. All rights reserved Received: 2nd February 2016; Revised: 26th April 2016; Accepted: 7th June 2016 How to Cite: Cai, K.Y., Liu, Y.S., Song, M., Zhou, Y.M., Liu, Q., Wang, X.H. (2016. Preparation of FeO(OH Modified with Polyethylene Glycol and Its Catalytic Activity on the Reduction of Nitrobenzene with Hydrazine Hydrate. Bulletin of Chemical Reaction Engineering & Catalysis, 11 (3: 363-368 (doi:10.9767/bcrec.11.3.576.363-368 Permalink/DOI: http://doi.org/10.9767/bcrec.11.3.576.363-368

  19. Complexation of carboxylate on smectite surfaces.

    Science.gov (United States)

    Liu, Xiandong; Lu, Xiancai; Zhang, Yingchun; Zhang, Chi; Wang, Rucheng

    2017-07-19

    We report a first principles molecular dynamics (FPMD) study of carboxylate complexation on clay surfaces. By taking acetate as a model carboxylate, we investigate its inner-sphere complexes adsorbed on clay edges (including (010) and (110) surfaces) and in interlayer space. Simulations show that acetate forms stable monodentate complexes on edge surfaces and a bidentate complex with Ca 2+ in the interlayer region. The free energy calculations indicate that the complexation on edge surfaces is slightly more stable than in interlayer space. By integrating pK a s and desorption free energies of Al coordinated water calculated previously (X. Liu, X. Lu, E. J. Meijer, R. Wang and H. Zhou, Geochim. Cosmochim. Acta, 2012, 81, 56-68; X. Liu, J. Cheng, M. Sprik, X. Lu and R. Wang, Geochim. Cosmochim. Acta, 2014, 140, 410-417), the pH dependence of acetate complexation has been revealed. It shows that acetate forms inner-sphere complexes on (110) in a very limited mildly acidic pH range while it can complex on (010) in the whole common pH range. The results presented in this study form a physical basis for understanding the geochemical processes involving clay-organics interactions.

  20. The effects of daily chlorhexidine bathing on cutaneous bacterial isolates: a pilot study

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    Soma VL

    2012-04-01

    Full Text Available Vijaya L Soma1, Xuan Qin2, Chuan Zhou1, Amanda Adler1, Jessica E Berry2, Danielle M Zerr11Department of Pediatrics, 2Department of Laboratory Medicine, University of Washington, Seattle, WA, USAAbstract: Chlorhexidine gluconate (CHG is a topical antiseptic used in a myriad of clinical settings. Recently, CHG baths have been shown to decrease multidrug-resistant organism acquisition and infections and catheter-associated bloodstream infections. The present study examined the effects of daily bathing with CHG on the recovery and antimicrobial susceptibility of cultivable cutaneous bacteria. The objectives of this study were to (1 explore the effects of clinical CHG bathing on cultivable cutaneous bacteria, (2 study the relationship between CHG minimum inhibitory concentration and antimicrobial susceptibility of coagulase-negative staphylococci, and (3 demonstrate the feasibility of the approach so a more definitive study may be performed. Significant decreases in bacterial colony counts and phenotypic diversity occurred with greater CHG exposure. The findings also suggest an inverse relationship between CHG minimum inhibitory concentration and antimicrobial susceptibility. Larger prospective studies are necessary to fully investigate the clinical impact of CHG usage.Keywords: antiseptic, resistance, Staphylococcus, coagulase-negative

  1. [Revision to origin of northern Artemisia argyi in Compendium of Materia Medica (Bencao gangmu)].

    Science.gov (United States)

    Huang, Lu-qi; Qiu, Le

    2014-12-01

    The origin of northern Artemisia argyi recorded in Compendium of Materia Medica(Bencao gangmu) is Fudao(Chinese characters) in Tangyin county, While there is only Fudao(Chinese characters) instead of Fudao(Chinese characters). Whether indeed Fudao(Chinese characters) is Fudao(Chinese characters)? By reviewing the genuine evolution of A. argyi, doing textual research on Fudao(Chinese characters) and combing with field survey data of national census of Chinese Materia Medica resources, this paper concluded that the word Fudao(Chinese characters) firstly emerged in Figure Canon of Chinese Materia Medica(Bencao tujing) of Susong in Song dynasty and was applied in later generations, but the implication was not clear, then emerged both Tangyin and Fudao(Chinese characters) in Compendium of Materia Medica(Bencao gangmu). The place Fudao(Chinese characters) is one of the graves of Bianque, that existed from Shang and Zhou dynasty and never changed until now, the A. argyi of Tangyin was famous from the grave of Bianque in Fudao(Chinese characters), which could infer that Lishizhen considered Fudao (Chinese characters) was Fudao(Chinese characters) indeed, and the origin of northern A. argyi was Fudao(Chinese characters) in Tangyin county.

  2. A new theoretical probe for the magnetic force microscope

    Energy Technology Data Exchange (ETDEWEB)

    Windmill, J.F.C. E-mail: jwindmill@plymouth.ac.uk; Clegg, W.W.; Jenkins, D.F.L.; Davey, P.J

    2001-05-01

    The magnetic force microscope (MFM) is established as a valuable tool for the analysis of magnetic structures. The standard design of MFM incorporates a silicon tip coated with a magnetic material. However, these tips are subject to several inherent problems, e.g. changing characteristics over time due to damage or magnetic hysteresis. A new theoretical electromagnetic MFM probe is introduced here. Although electromagnetic MFM has been discussed before by Zhou et al. (J. Vac. Sci. Technol. A 17 (1999) 2233), the design presented here is a different approach. Two different probe iterations and their magnetic field intensity distribution are modelled. The probe imaging capability is compared using the reciprocity principle (Wright and Hill, Appl. Phys. Lett. 68 (1996) 1726) to image the simulated force interaction between a sample and the probe fields. Thus, images of a sample's magnetic distribution are produced by the convolution of the different probe gradient field distributions and the sample magnetisation. Both perpendicular and longitudinal magnetisation patterns were simulated with the different probe iterations. This clearly showed the improvement of the second probe iteration, particularly for longitudinal patterns. The practical use of the new probe is also discussed, and future work outlined.

  3. A polarized hydrogen/deuterium atomic beam source for internal target experiments

    International Nuclear Information System (INIS)

    Szczerba, D.; Buuren, L.D. van; Brand, J.F.J. van den; Bulten, H.J.; Ferro-Luzzi, M.; Klous, S.; Kolster, H.; Lang, J.; Mul, F.; Poolman, H.R.; Simani, M.C.

    2000-01-01

    A high-brightness hydrogen/deuterium atomic beam source is presented. The apparatus, previously used in electron scattering experiments with tensor-polarized deuterium (Ferro-Luzzi et al., Phys. Rev. Lett. 77 (1996) 2630; van den Brand et al., Phys. Rev. Lett. 78 (1997) 1235; Zhou et al., Phys. Rev. Lett. 82 (1998) 687; Bouwhuis et al., Phys. Rev. Lett. 82 (1999) 3755), was configured as a source for internal target experiments to measure single- and double-polarization observables, with either polarized hydrogen or vector/tensor polarized deuterium. The atomic beam intensity was enhanced by a factor of ∼2.5 by optimizing the Stern-Gerlach focusing system using high tip-field (∼1.5 T) rare-earth permanent magnets, and by increasing the pumping speed in the beam-formation chamber. Fluxes of (5.9±0.2)x10 16 1 H/s were measured in a diameter 12 mmx122 mm compression tube with its entrance at a distance of 27 cm from the last focusing element. The total output flux amounted to (7.6±0.2)x10 16 1 H/s

  4. Isolated guitar transcription using a deep belief network

    Directory of Open Access Journals (Sweden)

    Gregory Burlet

    2017-03-01

    Full Text Available Music transcription involves the transformation of an audio recording to common music notation, colloquially referred to as sheet music. Manually transcribing audio recordings is a difficult and time-consuming process, even for experienced musicians. In response, several algorithms have been proposed to automatically analyze and transcribe the notes sounding in an audio recording; however, these algorithms are often general-purpose, attempting to process any number of instruments producing any number of notes sounding simultaneously. This paper presents a polyphonic transcription algorithm that is constrained to processing the audio output of a single instrument, specifically an acoustic guitar. The transcription system consists of a novel note pitch estimation algorithm that uses a deep belief network and multi-label learning techniques to generate multiple pitch estimates for each analysis frame of the input audio signal. Using a compiled dataset of synthesized guitar recordings for evaluation, the algorithm described in this work results in an 11% increase in the f-measure of note transcriptions relative to Zhou et al.’s (2009 transcription algorithm in the literature. This paper demonstrates the effectiveness of deep, multi-label learning for the task of polyphonic transcription.

  5. Systematic review and meta-analysis: bezafibrate in patients with primary biliary cirrhosis

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    Yin Q

    2015-09-01

    Full Text Available Qin Yin,1,2,* Jingjing Li,3,* Yujing Xia,3 Rong Zhang,3,4 Jianrong Wang,3,4 Wenxia Lu,3,4 Yuqing Zhou,1,2 Yuanyuan Zheng,3 Huerxidan Abudumijiti,3 Rongxia Chen,3 Kan Chen,3 Sainan Li,3 Tong Liu,3 Fan Wang,3 Jie Lu,3 Yingqun Zhou,3 Chuanyong Guo3 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2The First Affiliated Hospital of Soochow University, Suzhou, 3Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 4The First Clinical Medical College of Nanjing Medical University, Nanjing, People’s Republic of China *These authors contributed equally to this work and should be considered co-first authors Background and aim: Ursodeoxycholic acid (UDCA is the standard treatment for primary biliary cirrhosis (PBC, but not all cases respond well. Evidence has shown that combination therapy of UDCA with bezafibrate significantly improved liver function. A meta-analysis was performed to assess the efficacy and safety of UDCA and bezafibrate combination therapy in the treatment of PBC.Results: Nine trials, with a total of 269 patients, were included in the analysis. The bias risk of these trials was high. Compared with UDCA alone, the combination with bezafibrate improved the Mayo risk score (mean difference [MD], 0.60; 95% confidence interval [CI], 0.25–0.95; P=0.0008 and liver biochemistry: alkaline phosphatase (MD, -238.21 IU/L; 95% CI, -280.83 to -195.60; P<0.00001; gamma-glutamyltransferase (MD, -38.23 IU/L; 95% CI, -50.16 to -25.85; P<0.00001; immunoglobulin M (MD, -128.63 IU/L; 95% CI, -151.55 to -105.71; P<0.00001; bilirubin (MD, -0.20 mg/dL; 95% CI, -0.33 to -0.07; P=0.002; triglycerides (MD, -26.84 mg/dL; 95% CI, -36.51 to -17.17; P<0.0001; total cholesterol (MD, -21.58 mg/dL; 95% CI, -30.81 to -12.34; P<0.0001, and serum alanine aminotransferase (MD, -10.24 IU/L; 95% CI, -12.65 to -78.5; P<0.00001. However

  6. A study on the hemocompatibility of dendronized chitosan derivatives in red blood cells

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    Zhou YF

    2015-05-01

    Full Text Available Yanfang Zhou,1,* Jiemei Li,1,* Fang Lu,1 Junjie Deng,2 Jiahua Zhang,1 Peijie Fang,1 Xinsheng Peng,1 Shu-Feng Zhou3 1Guangdong Medical Universtity, Dongguan, Guangdong, People’s Republic of China; 2Department of Materials Science and Engineering, Drexel University, Philadelphia, PA, USA; 3Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA *These authors contributed equally to this work Abstract: Dendrimers are hyperbranched macromolecules with well-defined topological structures and multivalent functionalization sites, but they may cause cytotoxicity due to the presence of cationic charge. Recently, we have introduced alkyne-terminated poly(amidoamine (PAMAM dendrons of different generations (G=2,3 into chitosan to obtain dendronized chitosan derivatives [Cs-g-PAMAM (G=2,3], which exhibited a better water solubility and enhanced plasmid DNA transfection efficiency. In this study, we attempted to examine the impact of Cs-g-PAMAM (G=2,3 at different concentrations (25 µg/mL, 50 µg/mL, and 100 µg/mL on the morphology, surface structure, and viability of rat red blood cells (RBCs. The results showed that treatment of RBCs with Cs-g-PAMAM (G=2,3 at 50 µg/mL and 100 µg/mL induced a slightly higher hemolysis than Cs, and Cs-g-PAMAM (G=3 caused a slightly higher hemolysis than Cs-g-PAMAM (G=2, but all values were <5.0%. Optical microscopic and atomic force microscopic examinations indicated that Cs-g-PAMAM (G=2,3 caused slight RBC aggregation and lysis. Treatment of RBCs with 100 µg/mL Cs-g-PAMAM (G=3 induced echinocytic transformation, and RBCs displayed characteristic irregular contour due to the folding of the periphery. Drephanocyte-like RBCs were observed when treated with 100 µg/mL Cs-g-PAMAM (G=3. Erythrocytes underwent similar shape transition upon treatment with Cs-g-PAMAM (G=2 or Cs. The roughness values (Rms of RBCs incubated with Cs-g-PAMAM (G=2,3 were significantly larger

  7. Association of 5' end neuregulin-1 (NRG1) gene variation with subcortical medial frontal microstructure in humans.

    Science.gov (United States)

    Winterer, Georg; Konrad, Andreas; Vucurevic, Goran; Musso, Francesco; Stoeter, Peter; Dahmen, Norbert

    2008-04-01

    Animal data suggest that the gene neuregulin-1 (NRG1) is involved in neuronal myelination. A haplotype (deCODE) in the 5' end region of the gene was described to double the risk for schizophrenia in an Icelandic population (Stefansson, H., Sigurdsson, E., Steinthorsdottir, V., Bjornsdottir, S., Sigmundsson, T., Ghosh, S., Brynjolfsson, J., Gunnarsdottir, S., Ivarsson, O., Chou, T.T., Hjaltason, O., Birgisdottir, B., Jonsson, H., Gudnadottir, V.G., Gudmundsdottir, E., Bjornsson, A., Ingvarsson, B., Ingason, A., Sigfusson, S., Hardardottir, H., Harvey, R.P., Lai, D., Zhou, M., Brunner, D., Mutel, V., Gonzalo, A., Lemke, G., Sainz, J., Johannesson, G., Andresson, T., Gudbjartsson, D., Manolescu, A., Frigge, M.L., Gurney, M.E., Kong, A., Gulcher, J.R., Petursson, H., Stefansson, K. 2002. Neuregulin-1 and susceptibility to schizophrenia. Am. J. Hum. Genet. 71, 877-892). Of note, there is now increasing evidence of disturbed myelination in this illness--particularly in subcortical frontal lobe white matter (Konrad, A., Winterer, G. 2008. Disturbed structural connectivity in schizophrenia--primary factor in pathology or epiphenomenon? Schiz. Bull. [Electronic publication ahead of print]). Therefore, we investigated with diffusion tensor imaging (DTI) the impact of a tagging single nucleotide polymorphism (SNP) from the deCODE haplotype, i.e., SNP8NRG221533, on fractional anisotropy (FA), which reflects structural integrity of white matter. SNP8NRG221533 was selected because it gave the single best uncorrected association with schizophrenia in the original report by Stefansson et al. (Stefansson, H., Sigurdsson, E., Steinthorsdottir, V., Bjornsdottir, S., Sigmundsson, T., Ghosh, S., Brynjolfsson, J., Gunnarsdottir, S., Ivarsson, O., Chou, T.T., Hjaltason, O., Birgisdottir, B., Jonsson, H., Gudnadottir, V.G., Gudmundsdottir, E., Bjornsson, A., Ingvarsson, B., Ingason, A., Sigfusson, S., Hardardottir, H., Harvey, R.P., Lai, D., Zhou, M., Brunner, D., Mutel, V., Gonzalo, A

  8. Reliable multi-label learning via conformal predictor and random forest for syndrome differentiation of chronic fatigue in traditional Chinese medicine.

    Directory of Open Access Journals (Sweden)

    Huazhen Wang

    Full Text Available OBJECTIVE: Chronic Fatigue (CF still remains unclear about its etiology, pathophysiology, nomenclature and diagnostic criteria in the medical community. Traditional Chinese medicine (TCM adopts a unique diagnostic method, namely 'bian zheng lun zhi' or syndrome differentiation, to diagnose the CF with a set of syndrome factors, which can be regarded as the Multi-Label Learning (MLL problem in the machine learning literature. To obtain an effective and reliable diagnostic tool, we use Conformal Predictor (CP, Random Forest (RF and Problem Transformation method (PT for the syndrome differentiation of CF. METHODS AND MATERIALS: In this work, using PT method, CP-RF is extended to handle MLL problem. CP-RF applies RF to measure the confidence level (p-value of each label being the true label, and then selects multiple labels whose p-values are larger than the pre-defined significance level as the region prediction. In this paper, we compare the proposed CP-RF with typical CP-NBC(Naïve Bayes Classifier, CP-KNN(K-Nearest Neighbors and ML-KNN on CF dataset, which consists of 736 cases. Specifically, 95 symptoms are used to identify CF, and four syndrome factors are employed in the syndrome differentiation, including 'spleen deficiency', 'heart deficiency', 'liver stagnation' and 'qi deficiency'. THE RESULTS: CP-RF demonstrates an outstanding performance beyond CP-NBC, CP-KNN and ML-KNN under the general metrics of subset accuracy, hamming loss, one-error, coverage, ranking loss and average precision. Furthermore, the performance of CP-RF remains steady at the large scale of confidence levels from 80% to 100%, which indicates its robustness to the threshold determination. In addition, the confidence evaluation provided by CP is valid and well-calibrated. CONCLUSION: CP-RF not only offers outstanding performance but also provides valid confidence evaluation for the CF syndrome differentiation. It would be well applicable to TCM practitioners and

  9. Effects of marital status on survival of hepatocellular carcinoma by race/ethnicity and gender

    Directory of Open Access Journals (Sweden)

    Wu W

    2018-01-01

    Full Text Available Wenrui Wu,1,2 Daiqiong Fang,1,2 Ding Shi,1,2 Xiaoyuan Bian,1,2 Lanjuan Li1,2 1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 2Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, People’s Republic of China Purpose: It is well demonstrated that being married is associated with a better prognosis in multiple types of cancer. However, whether the protective effect of marital status varied across race/ethnicity and gender in patients with hepatocellular carcinoma remains unclear. Therefore, we aimed to evaluate the roles of race/ethnicity and gender in this relationship.Patients and methods: We identified eligible patients from Surveillance, Epidemiology and End Results (SEER database during 2004–2012. Overall and cancer-specific survival differences across marital status were compared by Kaplan–Meier curves. We also estimated crude hazard ratios (CHRs and adjusted hazard ratios (AHRs with 95% confidence intervals (CIs for marital status associated with survival by race/ethnicity and gender in Cox proportional hazard models.Results: A total of 12,168 eligible patients diagnosed with hepatocellular carcinoma were included. We observed that married status was an independent protective prognostic factor for overall and cancer-specific survival. In stratified analyses by race/ethnicity, the AHR of overall mortality (unmarried vs married was highest for Hispanic (AHR =1.25, 95% CI, 1.13–1.39; P<0.001 and lowest for Asian or Pacific Islander (AHR =1.13; 95% CI, 1.00–1.28; P=0.042. Stratified by gender, the AHR was higher in males (AHR =1.27; 95% CI, 1.20–1.33; P<0.001.Conclusion: We demonstrated that married patients obtained better survival advantages. Race/ethnicity and gender could influence the magnitude of associations between marital status and risk of mortality. Keywords: primary hepatocellular

  10. A Study of Moisture Sorption and Dielectric Processes of Starch and Sodium Starch Glycolate : Theme: Formulation and Manufacturing of Solid Dosage Forms Guest Editors: Tony Zhou and Tonglei Li.

    Science.gov (United States)

    Hiew, Tze Ning; Huang, Rongying; Popov, Ivan; Feldman, Yuri; Heng, Paul Wan Sia

    2017-12-01

    This study explored the potential of combining the use of moisture sorption isotherms and dielectric relaxation profiles of starch and sodium starch glycolate (SSG) to probe the location of moisture in dried and hydrated samples. Starch and SSG samples, dried and hydrated, were prepared. For hydrated samples, their moisture contents were determined. The samples were probed by dielectric spectroscopy using a frequency band of 0.1 Hz to 1 MHz to investigate their moisture-related relaxation profiles. The moisture sorption and desorption isotherms of starch and SSG were generated using a vapor sorption analyzer, and modeled using the Guggenheim-Anderson-de Boer equation. A clear high frequency relaxation process was detected in both dried and hydrated starches, while for dried starch, an additional slower low frequency process was also detected. The high frequency relaxation processes in hydrated and dried starches were assigned to the coupled starch-hydrated water relaxation. The low frequency relaxation in dried starch was attributed to the local chain motions of the starch backbone. No relaxation process associated with water was detected in both hydrated and dried SSG within the frequency and temperature range used in this study. The moisture sorption isotherms of SSG suggest the presence of high energy free water, which could have masked the relaxation process of the bound water during dielectric measurements. The combined study of moisture sorption isotherms and dielectric spectroscopy was shown to be beneficial and complementary in probing the effects of moisture on the relaxation processes of starch and SSG.

  11. Hierarchical neural network model of the visual system determining figure/ground relation

    Science.gov (United States)

    Kikuchi, Masayuki

    2017-07-01

    One of the most important functions of the visual perception in the brain is figure/ground interpretation from input images. Figural region in 2D image corresponding to object in 3D space are distinguished from background region extended behind the object. Previously the author proposed a neural network model of figure/ground separation constructed on the standpoint that local geometric features such as curvatures and outer angles at corners are extracted and propagated along input contour in a single layer network (Kikuchi & Akashi, 2001). However, such a processing principle has the defect that signal propagation requires manyiterations despite the fact that actual visual system determines figure/ground relation within the short period (Zhou et al., 2000). In order to attain speed-up for determining figure/ground, this study incorporates hierarchical architecture into the previous model. This study confirmed the effect of the hierarchization as for the computation time by simulation. As the number of layers increased, the required computation time reduced. However, such speed-up effect was saturatedas the layers increased to some extent. This study attempted to explain this saturation effect by the notion of average distance between vertices in the area of complex network, and succeeded to mimic the saturation effect by computer simulation.

  12. Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway [Corrigendum

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    Zhou X

    2017-04-01

    Full Text Available Zhou X, Chen X, Cai JJ, et al. Drug Des Devel Ther. 2015;9: 4599–4611. On page 4600, the product type and source of the relaxin used in these experiments was missed from the ‘Materials and methods’ section. Under the subheading ‘Rat model of cardiac fibrosis’ the second paragraph should read: Rats were randomly divided into five groups (ten per group for treatment: control; myocardial fibrosis (isoproterenol [Iso]; and low-, middle-, and high-dose RLX (0.2, 2, and 20 μg⋅kg-1⋅day-1, respectively. RLX was obtained from Peprotech, Rocky Hill, NJ, USA (product number 130-15. For the Iso-model, on days 1–6, Iso (5 mg⋅kg-1⋅d-1; Sigma-Aldrich Co., St Louis, MO, USA was injected subcutaneously in the rats. In the therapeutic groups, Iso administration was the same as in the Iso-model group, and RLX at different concentrations (0.2, 2.0, and 20 μg⋅kg-1⋅day-1 were injected at the same time as Iso injection and lasted for 6 days, then RLX injection was continued for another 8 days. The same volume of saline was injected for controls.Read the original article.

  13. A recurrent neural model for proto-object based contour integration and figure-ground segregation.

    Science.gov (United States)

    Hu, Brian; Niebur, Ernst

    2017-12-01

    Visual processing of objects makes use of both feedforward and feedback streams of information. However, the nature of feedback signals is largely unknown, as is the identity of the neuronal populations in lower visual areas that receive them. Here, we develop a recurrent neural model to address these questions in the context of contour integration and figure-ground segregation. A key feature of our model is the use of grouping neurons whose activity represents tentative objects ("proto-objects") based on the integration of local feature information. Grouping neurons receive input from an organized set of local feature neurons, and project modulatory feedback to those same neurons. Additionally, inhibition at both the local feature level and the object representation level biases the interpretation of the visual scene in agreement with principles from Gestalt psychology. Our model explains several sets of neurophysiological results (Zhou et al. Journal of Neuroscience, 20(17), 6594-6611 2000; Qiu et al. Nature Neuroscience, 10(11), 1492-1499 2007; Chen et al. Neuron, 82(3), 682-694 2014), and makes testable predictions about the influence of neuronal feedback and attentional selection on neural responses across different visual areas. Our model also provides a framework for understanding how object-based attention is able to select both objects and the features associated with them.

  14. A three-dimensional constitutive model for shape memory alloy

    International Nuclear Information System (INIS)

    Zhou, Bo; Yoon, Sung-Ho; Leng, Jin-Song

    2009-01-01

    Shape memory alloy (SMA) has a wide variety of practical applications due to its unique super-elasticity and shape memory effect. It is of practical interest to establish a constitutive model which predicts its phase transformation and mechanical behaviors. In this paper, a new three-dimensional phase transformation equation, which predicts the phase transformation behaviors of SMA, is developed based on the results of a differential scanning calorimetry (DSC) test. It overcomes both limitations: that Zhou's phase transformation equations fail to describe the phase transformation from twinned martensite to detwinned martensite of SMA and Brinson's phase transformation equation fails to express the influences of phase transformation peak temperatures on the phase transformation behaviors of SMA. A new three-dimensional constitutive equation, which predicts the mechanical behaviors associated with the super-elasticity and shape memory effect of SMA, is developed on the basis of thermodynamics and solid mechanics. Results of numerical simulations show that the new constitutive model, which includes the new phase transformation equation and constitutive equation, can predict the phase transformation and mechanical behaviors associated with the super-elasticity and shape memory effect of SMA precisely and comprehensively. It is proved that Brinson's constitutive model of SMA can be considered as one special case of the new constitutive model

  15. Characterization Results for the L(2, 1, 1-Labeling Problem on Trees

    Directory of Open Access Journals (Sweden)

    Zhang Xiaoling

    2017-08-01

    Full Text Available An L(2, 1, 1-labeling of a graph G is an assignment of non-negative integers (labels to the vertices of G such that adjacent vertices receive labels with difference at least 2, and vertices at distance 2 or 3 receive distinct labels. The span of such a labelling is the difference between the maximum and minimum labels used, and the minimum span over all L(2, 1, 1-labelings of G is called the L(2, 1, 1-labeling number of G, denoted by λ2,1,1(G. It was shown by King, Ras and Zhou in [The L(h, 1, 1-labelling problem for trees, European J. Combin. 31 (2010 1295–1306] that every tree T has Δ2(T − 1 ≤ λ2,1,1(T ≤ Δ2(T, where Δ2(T = maxuv∈E(T(d(u + d(v. And they conjectured that almost all trees have the L(2, 1, 1-labeling number attain the lower bound. This paper provides some sufficient conditions for λ2,1,1(T = Δ2(T. Furthermore, we show that the sufficient conditions we provide are also necessary for trees with diameter at most 6.

  16. Determination of Important Topographic Factors for Landslide Mapping Analysis Using MLP Network

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    Mutasem Sh. Alkhasawneh

    2013-01-01

    Full Text Available Landslide is one of the natural disasters that occur in Malaysia. Topographic factors such as elevation, slope angle, slope aspect, general curvature, plan curvature, and profile curvature are considered as the main causes of landslides. In order to determine the dominant topographic factors in landslide mapping analysis, a study was conducted and presented in this paper. There are three main stages involved in this study. The first stage is the extraction of extra topographic factors. Previous landslide studies had identified mainly six topographic factors. Seven new additional factors have been proposed in this study. They are longitude curvature, tangential curvature, cross section curvature, surface area, diagonal line length, surface roughness, and rugosity. The second stage is the specification of the weight of each factor using two methods. The methods are multilayer perceptron (MLP network classification accuracy and Zhou's algorithm. At the third stage, the factors with higher weights were used to improve the MLP performance. Out of the thirteen factors, eight factors were considered as important factors, which are surface area, longitude curvature, diagonal length, slope angle, elevation, slope aspect, rugosity, and profile curvature. The classification accuracy of multilayer perceptron neural network has increased by 3% after the elimination of five less important factors.

  17. First-year university students’ receptive and productive use of academic vocabulary

    Directory of Open Access Journals (Sweden)

    Déogratias Nizonkiza

    2016-05-01

    Full Text Available The present study explores academic vocabulary knowledge, operationalised through the Academic Word List, among first-year higher education students. Both receptive and productive knowledge and the proportion between the two are examined. Results show that while receptive knowledge is readily acquired by first-year students, productive knowledge lags behind and remains problematic. This entails that receptive knowledge is much larger than productive knowledge, which confirms earlier indications that receptive vocabulary knowledge is larger than productive knowledge for both academic vocabulary (Zhou 2010 and general vocabulary (cf. Laufer 1998, Webb 2008, among others. Furthermore, results reveal that the ratio between receptive and productive knowledge is slightly above 50%, which lends empirical support to previous findings that the ratio between the two aspects of vocabulary knowledge can be anywhere between 50% and 80% (Milton 2009. This finding is extended here to academic vocabulary; complementing Zhou’s (2010 study that investigated the relationship between the two aspects of vocabulary knowledge without examining the ratio between them. On the basis of these results, approaches that could potentially contribute to fostering productive knowledge growth are discussed. Avenues worth exploring to gain further insight into the relationship between receptive and productive knowledge are also suggested.

  18. Full Waveform Inversion of Diving & Reflected Waves based on Scale Separation for Velocity and Impedance Imaging

    Science.gov (United States)

    Brossier, Romain; Zhou, Wei; Operto, Stéphane; Virieux, Jean

    2015-04-01

    Full Waveform Inversion (FWI) is an appealing method for quantitative high-resolution subsurface imaging (Virieux et al., 2009). For crustal-scales exploration from surface seismic, FWI generally succeeds in recovering a broadband of wavenumbers in the shallow part of the targeted medium taking advantage of the broad scattering-angle provided by both reflected and diving waves. In contrast, deeper targets are often only illuminated by short-spread reflections, which favor the reconstruction of the short wavelengths at the expense of the longer ones, leading to a possible notch in the intermediate part of the wavenumber spectrum. To update the velocity macromodel from reflection data, image-domain strategies (e.g., Symes & Carazzone, 1991) aim to maximize a semblance criterion in the migrated domain. Alternatively, recent data-domain strategies (e.g., Xu et al., 2012, Ma & Hale, 2013, Brossier et al., 2014), called Reflection FWI (RFWI), inspired by Chavent et al. (1994), rely on a scale separation between the velocity macromodel and prior knowledge of the reflectivity to emphasize the transmission regime in the sensitivity kernel of the inversion. However, all these strategies focus on reflected waves only, discarding the low-wavenumber information carried out by diving waves. With the current development of very long-offset and wide-azimuth acquisitions, a significant part of the recorded energy is provided by diving waves and subcritical reflections, and high-resolution tomographic methods should take advantage of all types of waves. In this presentation, we will first review the issues of classical FWI when applied to reflected waves and how RFWI is able to retrieve the long wavelength of the model. We then propose a unified formulation of FWI (Zhou et al., 2014) to update the low wavenumbers of the velocity model by the joint inversion of diving and reflected arrivals, while the impedance model is updated thanks to reflected wave only. An alternate inversion of

  19. Eugenics discourse and racial improvement in Republican China (1911-1949).

    Science.gov (United States)

    Sihn, Kyu-hwan

    2010-12-31

    This paper aimed to examine the advent of eugenics and its characteristics in republican China. Although eugenics was introduced into China as a discourse to preserve and improve race by the 1898 reformers such as Yan Fu (1854-1921) and Yi Nai (1875-?) in the late imperial period, it was not until the republican period that eugenics discourse started to combine with the discourse and movement related to social reform. The May 4th intellectuals put forward criticisms of Confucian patriarchy, propagating science and democracy. They pointed out that the large family system was a source of every social evil, and argued the need for a small family system based on monogamy. The aim of the small family system was to improve both the race and the environment. Such thinkers argued that freedom of love and the liberation of individuality were necessary for this end. Zhou Jianren (1888-1984), Lu Xun's youngest brother and representative eugenicist in the May 4th period, combined eugenics with freedom of love and the liberation of individuality. Pan Guangdan (1899-1967) and Zhou Jianren debated the eugenics controversy in the 1920s. They raised the freedom of love and the liberation of individuality as central issues related to the eugenics controversy. The eugenics debate was developed into the controversy between biological determinism and environmentalism in the late 1920s. However, these issues did not continue to be brought up in the 1930s. The main issues concerning the eugenics controversy in the 1930s were cultural identity and the population problem. Particularly in the 1930s, the scope of birth control as the solution to the population problem was extended from the individual person and family to nation and race. For eugenicists like Pan Guangdan, birth control violated the aim of eugenics and brought about the degeneration of the race. However, such theorists did not deny the value of birth control itself. The supporters of birth control thought that selecting

  20. Schisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathway

    Directory of Open Access Journals (Sweden)

    He JL

    2014-12-01

    Full Text Available Jin-Lian He,1 Zhi-Wei Zhou,2,3 Juan-Juan Yin,2 Chang-Qiang He,1 Shu-Feng Zhou,2,3 Yang Yu1 1College of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, People’s Republic of China; 2Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA; 3Guizhou Provincial Key Laboratory for Regenerative Medicine, Stem Cell and Tissue Engineering Research Center and Sino-US Joint Laboratory for Medical Sciences, Guiyang Medical University, Guiyang, Guizhou, People’s Republic of China Abstract: Drug metabolizing enzymes (DMEs and drug transporters are regulated via epigenetic, transcriptional, posttranscriptional, and translational and posttranslational modifications. Phase I and II DMEs and drug transporters play an important role in the disposition and detoxification of a large number of endogenous and exogenous compounds. The nuclear factor (erythroid-derived 2-like 2 (Nrf2 is a critical regulator of a variety of important cytoprotective genes that are involved in disposition and detoxification of xenobiotics. Schisandra chinensis (SC is a commonly used traditional Chinese herbal medicine that has been primarily used to protect the liver because of its potent antioxidative and anti-inflammatory activities. SC can modulate some DMEs and drug transporters, but the underlying mechanisms are unclear. In this study, we aimed to explore the role of Nrf2 in the regulatory effect of SC extract (SCE on selected DMEs and drug transporters in human hepatocellular liver carcinoma cell line (HepG2 cells. The results showed that SCE, schisandrin A, and schisandrin B significantly increased the expression of NAD(PH: Nicotinamide Adenine Dinucleotide Phosphate-oxidase or:quinone oxidoreductase 1, heme oxygenase-1, glutamate–cysteine ligase, and glutathione S-transferase A4 at both transcriptional and posttranscriptional levels. Incubation of HepG2 cells with SCE resulted in a significant

  1. A cognitive network for oracle-bone characters related to animals

    Science.gov (United States)

    Dress. Andreas; Grünewald, Stefan; Zeng, Zhenbing

    This paper is dedicated to HAO Bailin on the occasion of his eighties birthday, the great scholar and very good friend who never tired to introduce us to the wonderful and complex intricacies of Chinese culture and history. In this paper, we present an analysis of oracle-bone characters for animals from a `cognitive' point of view. After some general remarks on oraclebone characters presented in Section 1 and a short outline of the paper in Section 2, we collect various oracle-bone characters for animals from published resources in Section 3. In the next section, we begin analysing a group of 60 ancient animal characters from www.zdic.net, a highly acclaimed internet dictionary of Chinese characters that is strictly based on historical sources, and introduce five categories of specific features regarding their (graphical) structure that will be used in Section 5 to associate corresponding feature vectors to these characters. In Section 6, these feature vectors will be used to investigate their dissimilarity in terms of a family of parameterised distance measures. And in the last section, we apply the SplitsTree method as encoded in the NeighbourNet algorithms to construct a corresponding family of dissimilarity-based networks with the intention of elucidating how the ancient Chinese might have perceived the `animal world' in the late bronze age and to demonstrate that these pictographs reflect an intuitive understanding of this world and its inherent structure that predates its classification in the oldest surviving Chinese encyclopedia from approximately the 3rd century BC, the ErYa, as well as similar classification systems in the West by one to two millennia. We also present an English dictionary of 70 oracle-bone characters for animals in Appendix 1. In Appendix 2, we list various variants of animal characters that were published in the Jia Gu Wen Bian (cf. , A Complete Collection of Oracle Bone Characters, edited by the Institute of Archaeology of the Chinese

  2. Human Lung Cancer Risks from Radon – Part I - Influence from Bystander Effects - A Microdose Analysis

    Science.gov (United States)

    Leonard, Bobby E.; Thompson, Richard E.; Beecher, Georgia C.

    2010-01-01

    Since the publication of the BEIR VI report in 1999 on health risks from radon, a significant amount of new data has been published showing various mechanisms that may affect the ultimate assessment of radon as a carcinogen, at low domestic and workplace radon levels, in particular the Bystander Effect (BE) and the Adaptive Response radio-protection (AR). We analyzed the microbeam and broadbeam alpha particle data of Miller et al. (1995, 1999), Zhou et al. (2001, 2003, 2004), Nagasawa and Little (1999, 2002), Hei et al. (1999), Sawant et al. (2001a) and found that the shape of the cellular response to alphas is relatively independent of cell species and LET of the alphas. The same alpha particle traversal dose response behavior should be true for human lung tissue exposure to radon progeny alpha particles. In the Bystander Damage Region of the alpha particle response, there is a variation of RBE from about 10 to 35. There is a transition region between the Bystander Damage Region and Direct Damage Region of between one and two microdose alpha particle traversals indicating that perhaps two alpha particle “hits” are necessary to produce the direct damage. Extrapolation of underground miners lung cancer risks to human risks at domestic and workplace levels may not be valid. PMID:21731539

  3. Fluorinated cobalt for catalyzing hydrogen generation from sodium borohydride

    Energy Technology Data Exchange (ETDEWEB)

    Akdim, O.; Demirci, U.B.; Brioude, A.; Miele, P. [Laboratoire des Multimateriaux et Interfaces, UMR 5615 CNRS Universite Lyon 1, Universite de Lyon, 43 boulevard du 11 Novembre 1918, F-69622 Villeurbanne (France)

    2009-07-15

    The present paper reports preliminary results relating to a search for durable cobalt-based catalyst intended to catalyze the hydrolysis of sodium borohydride (NaBH{sub 4}). Fluorination of Co [Suda S, Sun YM, Liu BH, Zhou Y, Morimitsu S, Arai K, et al. Catalytic generation of hydrogen by applying fluorinated-metal hydrides as catalysts. Appl Phys A 2001; 72: 209-12.] has attracted our attention whereas the fluorination of Co boride has never been envisaged so far. Our first objective was to compare the reactivity of fluorinated Co with that of Co boride. We focused our attention on the formation of Co boride from fluorinated Co. Our second objective was to show the fluorination effect on the reactivity of Co. Our third objective was to find an efficient, durable Co catalyst. It was observed a limited stabilization of the Co surface by virtue of the fluorination, which made the formation of surface Co boride more difficult while the catalytic activity was unaltered. The fluorination did not affect the number of surface active sites. Nevertheless, it did not prevent the formation of Co boride. The fluorination of Co boride was inefficient. Hence, fluorination is a way to gain in stabilization of the catalytic surface but it is quite inefficient to hinder the boride formation. Accordingly, it did not permit to compare the reactivity of Co boride with that of Co. (author)

  4. Evaluating the Predictive Power of Multivariate Tensor-based Morphometry in Alzheimers Disease Progression via Convex Fused Sparse Group Lasso.

    Science.gov (United States)

    Tsao, Sinchai; Gajawelli, Niharika; Zhou, Jiayu; Shi, Jie; Ye, Jieping; Wang, Yalin; Lepore, Natasha

    2014-03-21

    Prediction of Alzheimers disease (AD) progression based on baseline measures allows us to understand disease progression and has implications in decisions concerning treatment strategy. To this end we combine a predictive multi-task machine learning method 1 with novel MR-based multivariate morphometric surface map of the hippocampus 2 to predict future cognitive scores of patients. Previous work by Zhou et al. 1 has shown that a multi-task learning framework that performs prediction of all future time points (or tasks) simultaneously can be used to encode both sparsity as well as temporal smoothness. They showed that this can be used in predicting cognitive outcomes of Alzheimers Disease Neuroimaging Initiative (ADNI) subjects based on FreeSurfer-based baseline MRI features, MMSE score demographic information and ApoE status. Whilst volumetric information may hold generalized information on brain status, we hypothesized that hippocampus specific information may be more useful in predictive modeling of AD. To this end, we applied Shi et al. 2 s recently developed multivariate tensor-based (mTBM) parametric surface analysis method to extract features from the hippocampal surface. We show that by combining the power of the multi-task framework with the sensitivity of mTBM features of the hippocampus surface, we are able to improve significantly improve predictive performance of ADAS cognitive scores 6, 12, 24, 36 and 48 months from baseline.

  5. The microbial community characteristics of ancient painted sculptures in Maijishan Grottoes, China.

    Science.gov (United States)

    Duan, Yulong; Wu, Fasi; Wang, Wanfu; He, Dongpeng; Gu, Ji-Dong; Feng, Huyuan; Chen, Tuo; Liu, Guangxiu; An, Lizhe

    2017-01-01

    In this study, a culture-independent Illumina MiSeq sequencing strategy was applied to investigate the microbial communities colonizing the ancient painted sculptures of the Maijishan Grottoes, a famous World Cultural Heritage site listed by UNESCO in China. Four mixed samples were collected from Cave 4-4 of the Maijishan Grottoes, the so-called Upper Seven Buddha Pavilion, which was built during the Northern Zhou Dynasty (557-581AD). The 16/18S rRNA gene-based sequences revealed a rich bacterial diversity and a relatively low fungal abundance, including the bacterial groups Actinobacteria, Acidobacteria, Bacteroidetes, Cyanobacteria, Chloroflexi, Firmicutes, Proteobacteria and Verrucomicrobia and the fungal groups Ascomycota, Basidiomycota and Chytridiomycota. Among them, the bacteria genera of Pseudonocardia and Rubrobacter and unclassified fungi in the order of Capnodiales were dominant. The relative abundance of Pseudonocardia in the painted layer samples was higher than that in the dust sample, while Cyanobacteria dominated in the dust sample. Many of them have been discovered at other cultural heritage sites and associated with the biodeterioration of cultural relics. The presence and activity of these pioneering microorganisms may lead to an unexpected deterioration of the painted sculptures that are preserved in this heritage site. Thus, proper management strategies and potential risk monitoring should be used in the Maijishan Grottoes to improve the conservation of these precious painted sculptures.

  6. Production of bacterial cellulose using different carbon sources and culture media.

    Science.gov (United States)

    Mohammadkazemi, Faranak; Azin, Mehrdad; Ashori, Alireza

    2015-03-06

    In this work, the effects of carbon sources and culture media on the production and structural properties of bacterial cellulose (BC) have been studied. BC nanofibers were synthesized using Gluconacetobacter xylinus strain PTCC 1734. Media used were Hestrin-Schramm (H), Yamanaka (Y), and Zhou (Z). Five different carbon sources, namely date syrup, glucose, mannitol, sucrose, and food-grade sucrose were used in these media. All the produced BC pellicles were characterized in terms of dry weight production, biomass yield, thermal stability, crystallinity and morphology by thermogravimetric analysis (TGA), x-ray diffraction (XRD), and field emission scanning electron microscopy (FE-SEM). The obtained results showed that mannitol lead to the highest yield, followed by sucrose. The highest production efficiency of mannitol might be due to the nitrogen source, which plays an important role. The maximum improvement on the thermal stability of the composites was achieved when mannitol was used in H medium. In addition, the crystallinity was higher in BC formed in H medium compared to other media. FE-SEM micrographs illustrated that the BC pellicles, synthesized in the culture media H and Z, were stable, unlike those in medium Y that were unstable. The micrographs of BC produced in media containing mannitol and sucrose provided evidence of the strong interfacial adhesion between the BC fibers without noticeable aggregates. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Remarks on transport theories of interplanetary fluctuations

    International Nuclear Information System (INIS)

    Ye Zhou; Matthaeus, W.H.

    1990-01-01

    The structure of approximate transport theories for the radial behavior of interplanetary fluctuations is reconsidered. The emphasis is on theories derived under the assumption of scale separation; i.e., the correlation length of the fluctuations is much less than the scale of large inhomogeneities. In these cases the zero-wavelength limit provides a first approximation to the spectral evolution equations for the radial dependence of interplanetary fluctuation spectra. The goal here is to investigate the structure of a recently presented (Zhou and Matthaeus, 1989) transport theory, in which coupling of inward- and outward-type fluctuations appears in the leading order, an effect the authors call mixing. In linear theory, mixing-type couplings of inward-type and outward-type waves are formally a nonresonant effect. However, leading order mixing terms do not vanish at zero wavelength for fluctuations that vary nearly perpendicular to the local magnetic field, or when the mean magnetic field is weak. Leading order mixing terms also survive when the dispersion relation fails and there is a nonunique relationship between frequency and wave number. The former case corresponds to nearly two-dimensional structures; these are included, for example, in isotropic models of turbulence. The latter instance occurs when wave-wave couplings are sufficiently strong. Thus there are a variety of situations in which leading order mixing effects are expected to be present

  8. A cubic map chaos criterion theorem with applications in generalized synchronization based pseudorandom number generator and image encryption.

    Science.gov (United States)

    Yang, Xiuping; Min, Lequan; Wang, Xue

    2015-05-01

    This paper sets up a chaos criterion theorem on a kind of cubic polynomial discrete maps. Using this theorem, Zhou-Song's chaos criterion theorem on quadratic polynomial discrete maps and generalized synchronization (GS) theorem construct an eight-dimensional chaotic GS system. Numerical simulations have been carried out to verify the effectiveness of theoretical results. The chaotic GS system is used to design a chaos-based pseudorandom number generator (CPRNG). Using FIPS 140-2 test suit/Generalized FIPS 140-2, test suit tests the randomness of two 1000 key streams consisting of 20 000 bits generated by the CPRNG, respectively. The results show that there are 99.9%/98.5% key streams to have passed the FIPS 140-2 test suit/Generalized FIPS 140-2 test. Numerical simulations show that the different keystreams have an average 50.001% same codes. The key space of the CPRNG is larger than 2(1345). As an application of the CPRNG, this study gives an image encryption example. Experimental results show that the linear coefficients between the plaintext and the ciphertext and the decrypted ciphertexts via the 100 key streams with perturbed keys are less than 0.00428. The result suggests that the decrypted texts via the keystreams generated via perturbed keys of the CPRNG are almost completely independent on the original image text, and brute attacks are needed to break the cryptographic system.

  9. Measurements of Positronium Formation Cross Sections for Positron-Kr, Xe Scattering

    Science.gov (United States)

    Kauppila, W. E.; Kwan, C. K.; Li, H.; Stein, T. S.; Zhou, S.

    1997-04-01

    Our experimental approach(S. Zhou et al., Phys. Rev. Lett. 73, 236 (1994).) for measuring Ps formation cross sections (Q_Ps) involves passing a variable energy positron beam through a gas scattering cell and detecting the 511 keV annihilation gamma rays resulting from the decay of para-Ps and from the interaction of ortho-Ps with the walls of the scattering cell. It is found that the Q_Ps curves for both Kr and Xe rise rapidly from their formation threshold energies of 7.2 and 5.3 eV, reach maxima within about 10 eV of their thresholds and then decrease to become rather small (less than 10% of the peak heights) above 100 eV. At the maxima Q_Ps accounts for more than 50% of the total scattering cross sections. There is some evidence of possible small scale structure in the Q_Ps curves between 10 and 100 eV. The present results are consistent with the prior measurements of Diana et al.( L.M. Diana et al., in "Atomic Physics with Positrons", edited by J.W. Humberston and E.A.G. Armour (Plenum, New York and London, 1987), p. 55; and in "Positron Annihilation", edited by L. Dorikens-Vanpraet et al. (World Scientific, Singapore, 1989), p. 311.) from near threshold to 70 eV for Kr and from 15 to 100 eV for Xe.

  10. Soliton Resolution for the Derivative Nonlinear Schrödinger Equation

    Science.gov (United States)

    Jenkins, Robert; Liu, Jiaqi; Perry, Peter; Sulem, Catherine

    2018-05-01

    We study the derivative nonlinear Schrödinger equation for generic initial data in a weighted Sobolev space that can support bright solitons (but exclude spectral singularities). Drawing on previous well-posedness results, we give a full description of the long-time behavior of the solutions in the form of a finite sum of localized solitons and a dispersive component. At leading order and in space-time cones, the solution has the form of a multi-soliton whose parameters are slightly modified from their initial values by soliton-soliton and soliton-radiation interactions. Our analysis provides an explicit expression for the correction dispersive term. We use the nonlinear steepest descent method of Deift and Zhou (Commun Pure Appl Math 56:1029-1077, 2003) revisited by the {\\overline{partial}} -analysis of McLaughlin and Miller (IMRP Int Math Res Pap 48673:1-77, 2006) and Dieng and McLaughlin (Long-time asymptotics for the NLS equation via dbar methods. Preprint, arXiv:0805.2807, 2008), and complemented by the recent work of Borghese et al. (Ann Inst Henri Poincaré Anal Non Linéaire, https://doi.org/10.1016/j.anihpc.2017.08.006, 2017) on soliton resolution for the focusing nonlinear Schrödinger equation. Our results imply that N-soliton solutions of the derivative nonlinear Schrödinger equation are asymptotically stable.

  11. Environmental Applications of Nanotechnology

    Science.gov (United States)

    Keller, Arturo A.

    2014-07-01

    Engineered nanomaterials (ENMs) are currently used in many applications including agriculture (Gruère, 2012; Khot et al. 2012; Lopez-Moreno et al. 2010; Peralta-Videa et al. 2011; Zhao et al. 2012), aerogels (Bigall et al. 2009), aerospace (Baur and Silverman, 2007), automotive (Coelho et al. 2012; Presting and König, 2003; Salonitis et al. 2010), catalysts (Zhou et al. 2011), coatings, paints and pigments (Dhoke et al. 2009; Gopalakrishnan et al. 2011; Khanna, 2008), composites (Borchardt, 2003; Khanna and Bakshi, 2009; Petrov and Georgiev, 2012; Sahoo et al. 2010), construction (Lee et al. 2010), cosmetics (Musee, 2011; Sabitha et al. 2012; Singh and Nanda, 2012), electronics and optics (Alda et al. 2005; Avasthi et al. 2007; Song et al. 2012; Subramanian and Takhee, 2012), energy (Serrano et al. 2009), environmental remediation (Dionysiou 2004; Khin et al. 2012), filtration and purification (Dhakras, 2011; Savage and Diallo, 2005), food products (Blasco and Picó, 2011; Weiss et al. 2006), medical (Boisseau and Loubaton, 2011; Farokhzad and Langer, 2006), packaging (Silvestre et al. 2011), paper and board (Kharisov and Kharissova, 2010), plastics, security (Marín and Merkoçi, 2012), sensors (Ding et al. 2010; Duncan et al. 2012; Su et al. 2012; Tan et al. 2012), and textiles (Qian and Hinestroza, 2004; Wong et al. 2006), and research is underway on many new applications...

  12. Investigation and Analysis on Psychological Health Situation for Middle and Primary School Students in Xianning City

    Directory of Open Access Journals (Sweden)

    Hong Yanping

    2015-01-01

    Full Text Available This paper is used to know about the psychological health situation for middle and primary school students in Xianning City and provide a certain empirical basis for meaningful development of psychological health education and psychological assistance. This paper uses the MHT scale prepared by Bucheng Zhou professor et al. to conduct a test for 1000 students in 7 middle and primary schools in Xianning City. The detection rate of psychological health problem accounts for 1.6% where the positive detection rate of study anxiety ranks first (43.2%. The psychological health situations have much difference in sex (t = -4. 624, P<0. 001, and it’s lower in male students than female ones. There is a significant difference between the psychological health situation for only and non-only children (t = -2. 519, P<0. 01.There is a significant difference on the psychological health situation for primary school, middle school and high school students (F = 11. 3, P<0. 001, and the psychological health situation of primary school students is better than that for middle school students. It can be concluded that the psychological health situation of middle and primary school students in Xianning City is fairly good, and the psychological health situation for male student, only children and primary school student is also fairly good.

  13. Molecular profiling of microbial communities from contaminated sources: Use of subtractive cloning methods and rDNA spacer sequences. 1998 annual progress report

    International Nuclear Information System (INIS)

    Robb, F.T.

    1998-01-01

    'The major objective of the research is to provide appropriate sequences and to assemble a high-density DNA array of oligonucleotides that can be used for rapid profiling of microbial populations from polluted areas. The sequences to be assigned to the DNA array are chosen from from cloned genomic DNA sequences (the ribosomal operon, described below) from groundwater at DOE sites containing organic solvents. The sites, Hanford Nuclear Plant and Lawrence Livermore Site 300, have well characterized pollutant histories, which have been provided by the collaborators. At this mid-point of the project, over 60 unique sequence classes of intergenic spacer region have been identified from the first sample site. The use of these sequences as hybridization probes, and their frequency of occurrence, allow a clear distinction between bacterial communities before and after remediation by acetate/nitrate pumping. The authors have developed the hybridization conditions for identifying PCR products in a 96 well format, a versatile alignment and visualization program (acronym: MALIGN) developed by Dr. Dennis Maeder, has been used to align the ISRs, which are variable in length and sometimes in position of the tRNAs. Finally, in collaboration with Dr. W. Chen and Dr. J. Zhou at ORNL, they have significant evidence that mass spectrometer analysis can be used to determine the lengths of PCR amplified intergenic spacer DNA.'

  14. Interdisciplinary treatment for an adult with a unilateral cleft lip and palate.

    Science.gov (United States)

    Ma, Qiao Ling; Conley, R Scott; Wu, Tuojiang; Li, Huang

    2014-08-01

    A young man, age 18 years 4 months, with a concave profile, a skeletal maxillary deficiency, and a severe alveolar cleft with an unesthetic appearance of the maxillary anterior teeth was referred for orthodontic treatment. After a detailed review of his pretreatment records, both surgical and nonsurgical treatment plans were presented to the patient, who opted for a nonsurgical interdisciplinary approach. His complex 3-dimensional malocclusion required palatal expansion, dental extractions, and periodontal and prosthodontic consultations and treatment, in addition to comprehensive orthodontic therapy. MBT (Xinya, HangZhou, China) 0.022 × 0.028-in appliances combined with a mini-implant to enhance the orthodontic anchorage were used to level, align, and establish a Class I relationship. After the orthodontic treatment, a combined restorative and periodontal approach was used to enhance the patient's esthetic and functional outcomes. Both the final result and the 1-year follow-up records demonstrate that the treatment goals of establishing proper occlusion, normal function, a balanced profile, better esthetics, and a stable outcome were achieved. The purpose of this case report is to demonstrate that an interdisciplinary treatment protocol can significantly improve the transverse discrepancies and achieve a satisfactory occlusion with a balanced profile in patients with cleft lip and palate. Copyright © 2014 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  15. Evaluating the predictive power of multivariate tensor-based morphometry in Alzheimer's disease progression via convex fused sparse group Lasso

    Science.gov (United States)

    Tsao, Sinchai; Gajawelli, Niharika; Zhou, Jiayu; Shi, Jie; Ye, Jieping; Wang, Yalin; Lepore, Natasha

    2014-03-01

    Prediction of Alzheimers disease (AD) progression based on baseline measures allows us to understand disease progression and has implications in decisions concerning treatment strategy. To this end we combine a predictive multi-task machine learning method1 with novel MR-based multivariate morphometric surface map of the hippocampus2 to predict future cognitive scores of patients. Previous work by Zhou et al.1 has shown that a multi-task learning framework that performs prediction of all future time points (or tasks) simultaneously can be used to encode both sparsity as well as temporal smoothness. They showed that this can be used in predicting cognitive outcomes of Alzheimers Disease Neuroimaging Initiative (ADNI) subjects based on FreeSurfer-based baseline MRI features, MMSE score demographic information and ApoE status. Whilst volumetric information may hold generalized information on brain status, we hypothesized that hippocampus specific information may be more useful in predictive modeling of AD. To this end, we applied Shi et al.2s recently developed multivariate tensor-based (mTBM) parametric surface analysis method to extract features from the hippocampal surface. We show that by combining the power of the multi-task framework with the sensitivity of mTBM features of the hippocampus surface, we are able to improve significantly improve predictive performance of ADAS cognitive scores 6, 12, 24, 36 and 48 months from baseline.

  16. In situ biosynthesis of bacterial nanocellulose-CaCO3 hybrid bionanocomposite: One-step process.

    Science.gov (United States)

    Mohammadkazemi, Faranak; Faria, Marisa; Cordeiro, Nereida

    2016-08-01

    In this work, a simple and green route to the synthesis of the bacterial nanocellulose-calcium carbonate (BNC/CaCO3) hybrid bionanocomposites using one-step in situ biosynthesis was studied. The CaCO3 was incorporated in the bacterial nanocellulose structure during the cellulose biosynthesis by Gluconacetobacter xylinus PTCC 1734 bacteria. Hestrin-Schramm (HS) and Zhou (Z) culture media were used to the hybrid bionanocomposites production and the effect of ethanol addition was investigated. Attenuated total reflection Fourier transform infrared spectroscopy, field emission scanning electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy, inverse gas chromatography and thermogravimetric analysis were used to characterize the samples. The experimental results demonstrated that the ethanol and culture medium play an important role in the BNC/CaCO3 hybrid bionanocomposites production, structure and properties. The BNC/CaCO3 biosynthesized in Z culture medium revealed higher O/C ratio and amphoteric surface character, which justify the highest CaCO3 content incorporation. The CaCO3 was incorporated into the cellulosic matrix decreasing the bacterial nanocellulose crystallinity. This work reveals the high potential of in situ biosynthesis of BNC/CaCO3 hybrid bionanocomposites and opens a new way to the high value-added applications of bacterial nanocellulose. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. A polyethylenimine-modified carboxyl-poly(styrene/acrylamide copolymer nanosphere for co-delivering of CpG and TGF-β receptor I inhibitor with remarkable additive tumor regression effect against liver cancer in mice

    Directory of Open Access Journals (Sweden)

    Liang SY

    2016-12-01

    Full Text Available Shuyan Liang,* Jun Hu,* Yuanyuan Xie, Qing Zhou, Yanhong Zhu, Xiangliang Yang National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, People’s Republic of China *These authors contributed equally to this work Abstract: Cancer immunotherapy based on nanodelivery systems has shown potential for treatment of various malignancies, owing to the benefits of tumor targeting of nanoparticles. However, induction of a potent T-cell immune response against tumors still remains a challenge. In this study, polyethylenimine-modified carboxyl-styrene/acrylamide (PS copolymer nanospheres were developed as a delivery system of unmethylated cytosine-phosphate-guanine (CpG oligodeoxynucleotides and transforming growth factor-beta (TGF-β receptor I inhibitors for cancer immunotherapy. TGF-β receptor I inhibitors (LY2157299, LY were encapsulated to the PS via hydrophobic interaction, while CpG oligodeoxynucleotides were loaded onto the PS through electrostatic interaction. Compared to the control group, tumor inhibition in the PS-LY/CpG group was up to 99.7% without noticeable toxicity. The tumor regression may be attributed to T-cell activation and amplification in mouse models. The results highlight the additive effect of CpG and TGF-β receptor I inhibitors co-delivered in cancer immunotherapy. Keywords: CpG, TGF-β receptor I inhibitor, Pst-AAm copolymer nanosphere, immunotherapy

  18. Toward Rotational State-Selective Photoionization of ThF+ Ions

    Science.gov (United States)

    Zhou, Yan; Ng, Kia Boon; Gresh, Dan; Cairncross, William; Grau, Matt; Ni, Yiqi; Cornell, Eric; Ye, Jun

    2016-06-01

    ThF+ has been chosen to replace HfF+ for a second-generation measurement of the electric dipole moment of the electron (eEDM). Compared to the currently running HfF+ eEDM experiment, ThF+ has several advantages: (i) the eEDM-sensitive state (3Δ1) is the ground state, which facilitates a long coherence time [1]; (ii) its effective electric field (35 GV/cm) is 50% larger than that of HfF+, which promises a direct increase of the eEDM sensitivity [2]; and (iii) the ionization energy of neutral ThF is lower than its dissociation energy, which introduces greater flexibility in rotational state-selective photoionization via core-nonpenetrating Rydberg states [3]. In this talk, we first present our strategy of preparing and utilizing core-nonpenetrating Rydberg states for rotational state-selective ionization. Then, we report spectroscopic data of laser-induced fluorescence of neutral ThF, which provides critical information for multi-photon ionization spectroscopy. [1] D. N. Gresh, K. C. Cossel, Y. Zhou, J. Ye, E. A. Cornell, Journal of Molecular Spectroscopy, 319 (2016), 1-9 [2] M. Denis, M. S. Nørby, H. J. A. Jensen, A. S. P. Gomes, M. K. Nayak, S. Knecht, T. Fleig, New Journal of Physics, 17 (2015) 043005. [3] Z. J. Jakubek, R. W. Field, Journal of Molecular Spectroscopy 205 (2001) 197-220.

  19. The Validity of Online Patient Ratings of Physicians: Analysis of Physician Peer Reviews and Patient Ratings.

    Science.gov (United States)

    McGrath, Robert J; Priestley, Jennifer Lewis; Zhou, Yiyun; Culligan, Patrick J

    2018-04-09

    Information from ratings sites are increasingly informing patient decisions related to health care and the selection of physicians. The current study sought to determine the validity of online patient ratings of physicians through comparison with physician peer review. We extracted 223,715 reviews of 41,104 physicians from 10 of the largest cities in the United States, including 1142 physicians listed as "America's Top Doctors" through physician peer review. Differences in mean online patient ratings were tested for physicians who were listed and those who were not. Overall, no differences were found between the online patient ratings based upon physician peer review status. However, statistical differences were found for four specialties (family medicine, allergists, internal medicine, and pediatrics), with online patient ratings significantly higher for those physicians listed as a peer-reviewed "Top Doctor" versus those who were not. The results of this large-scale study indicate that while online patient ratings are consistent with physician peer review for four nonsurgical, primarily in-office specializations, patient ratings were not consistent with physician peer review for specializations like anesthesiology. This result indicates that the validity of patient ratings varies by medical specialization. ©Robert J McGrath, Jennifer Lewis Priestley, Yiyun Zhou, Patrick J Culligan. Originally published in the Interactive Journal of Medical Research (http://www.i-jmr.org/), 09.04.2018.

  20. A cubic map chaos criterion theorem with applications in generalized synchronization based pseudorandom number generator and image encryption

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Xiuping, E-mail: yangxiuping-1990@163.com; Min, Lequan, E-mail: minlequan@sina.com; Wang, Xue, E-mail: wangxue-20130818@163.com [Schools of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083 (China)

    2015-05-15

    This paper sets up a chaos criterion theorem on a kind of cubic polynomial discrete maps. Using this theorem, Zhou-Song's chaos criterion theorem on quadratic polynomial discrete maps and generalized synchronization (GS) theorem construct an eight-dimensional chaotic GS system. Numerical simulations have been carried out to verify the effectiveness of theoretical results. The chaotic GS system is used to design a chaos-based pseudorandom number generator (CPRNG). Using FIPS 140-2 test suit/Generalized FIPS 140-2, test suit tests the randomness of two 1000 key streams consisting of 20 000 bits generated by the CPRNG, respectively. The results show that there are 99.9%/98.5% key streams to have passed the FIPS 140-2 test suit/Generalized FIPS 140-2 test. Numerical simulations show that the different keystreams have an average 50.001% same codes. The key space of the CPRNG is larger than 2{sup 1345}. As an application of the CPRNG, this study gives an image encryption example. Experimental results show that the linear coefficients between the plaintext and the ciphertext and the decrypted ciphertexts via the 100 key streams with perturbed keys are less than 0.00428. The result suggests that the decrypted texts via the keystreams generated via perturbed keys of the CPRNG are almost completely independent on the original image text, and brute attacks are needed to break the cryptographic system.

  1. Effect of onion flavonoids on colorectal cancer with hyperlipidemia: an in vivo study

    Directory of Open Access Journals (Sweden)

    He Y

    2014-01-01

    Full Text Available Yongshan He,1,* Heiying Jin,1,* Wei Gong,2,* Chunxia Zhang,1 Acheng Zhou1 1National Center of Colorectal Surgery, Third Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, People's Republic of China; 2Department of Surgery, Jiangyin Hospital of Traditional Chinese Medicine, Jiangyin, People's Republic of China *These authors contributed equally to this work Objectives: This study aims to find the effect of onion's extraction on the colorectal cancer with hyperlipidemia. Method: We established a hyperlipidemia-subcutaneously heterotopic colorectal cancer orthotopic transplant model and fed mice a high fat diet and performing transplantation. Animal models were treated with capecitabine and/or simvastatin and low-, middle-, high- dose of onion's extraction and both tumor growth rate and blood lipid levels were monitored. Results: We found that colorectal cancer in onion's extraction groups was significantly inhibited, and the effect of high dose of onion's extraction was equivalent to capecitabine. Onion's extraction effectively decreased levels of apoB and TC. Conclusion: Our study established a hyperlipidemia colon tumor model involving subcutaneous colon translocation and orthotopic transplantation, this model was an ideal research model for mutual influence of hyperlipidemia and colorectal cancer. Onion's extraction could inhibit the proliferation of colorectal cancer; the function of the high-dose of onion's extraction was fairly to capecitabine, which provided a new direction in protecting and treating colorectal cancer. Keywords: colorectal cancer, hyperlipidemia, onion flavonoids, capecitabine, simvastatin

  2. Improving protein disorder prediction by deep bidirectional long short-term memory recurrent neural networks.

    Science.gov (United States)

    Hanson, Jack; Yang, Yuedong; Paliwal, Kuldip; Zhou, Yaoqi

    2017-03-01

    Capturing long-range interactions between structural but not sequence neighbors of proteins is a long-standing challenging problem in bioinformatics. Recently, long short-term memory (LSTM) networks have significantly improved the accuracy of speech and image classification problems by remembering useful past information in long sequential events. Here, we have implemented deep bidirectional LSTM recurrent neural networks in the problem of protein intrinsic disorder prediction. The new method, named SPOT-Disorder, has steadily improved over a similar method using a traditional, window-based neural network (SPINE-D) in all datasets tested without separate training on short and long disordered regions. Independent tests on four other datasets including the datasets from critical assessment of structure prediction (CASP) techniques and >10 000 annotated proteins from MobiDB, confirmed SPOT-Disorder as one of the best methods in disorder prediction. Moreover, initial studies indicate that the method is more accurate in predicting functional sites in disordered regions. These results highlight the usefulness combining LSTM with deep bidirectional recurrent neural networks in capturing non-local, long-range interactions for bioinformatics applications. SPOT-disorder is available as a web server and as a standalone program at: http://sparks-lab.org/server/SPOT-disorder/index.php . j.hanson@griffith.edu.au or yuedong.yang@griffith.edu.au or yaoqi.zhou@griffith.edu.au. Supplementary data is available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  3. Fluorescence detection of tramadol in healthy Chinese volunteers by high-performance liquid chromatography and bioequivalence assessment

    Directory of Open Access Journals (Sweden)

    Zhou X

    2015-02-01

    Full Text Available Xiao Zhou, Ji Liu Department of Anesthesia, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China Abstract: This study developed a revised high-performance liquid chromatography fluorescence method to determine plasma tramadol concentration, and thereby to examine the bioequivalence of two tramadol formulations among healthy male Chinese volunteers. The study used a double-blind, randomized, 2×2 crossover-design principle. Calculated pharmacokinetic parameters for both formulations were consistent with previous reports. According to the observation of vital signs and laboratory measurement, no subjects had any adverse reactions. The geometric mean ratios (90% confidence interval of the test drug/reference drug for tramadol were 100.2% (95.3%–103.4% for the area under the plasma concentration–time curve (AUC from time zero to the last measurable concentration, 99.6% (94.2%–102.7% for the AUC from administration to infinite time, and 100.8% (93.1%–106.4% for maximum concentration. For the 90% confidence intervals of the test/reference AUC ratio and maximum concentration ratio of tramadol, both were in the acceptance range for bioequivalence. According to the two preparations by pharmacokinetic parameter statistics, the half-life, mean residence time, and clearance values showed no significant statistical differences. Therefore, the conclusion of this study was that the two tramadol formulations (tablets and capsules were bioequivalent. Keywords: tramadol hydrochloride, in vitro release, pharmacokinetic, bioequivalence, fluorescence detector

  4. Clinicopathological and prognostic significance of epithelial mesenchymal transition-related protein expression in intrahepatic cholangiocarcinoma

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    Yao X

    2012-10-01

    Full Text Available Xing Yao,1,* Xiang Wang,1,* Zishu Wang,2,* Licheng Dai,1 Guolei Zhang,1 Qiang Yan,1 Weimin Zhou11Huzhou Central Hospital, Zhejiang Huzhou, 2Department of Medical Oncology, First Affiliated Hospital, Bengbu Medical College, Anhui, People’s Republic of China *These authors contributed equally to this workBackground: The aim of this study was to examine the patterns of expression of epithelial-mesenchymal transition (EMT-related proteins in intrahepatic cholangiocarcinoma. The clinicopathological and prognostic value of these markers was also evaluated.Methods: We detected the expression status of three EMT-related proteins, ie, E-cadherin, vimentin, and N-cadherin, by immunohistochemistry in consecutive intrahepatic cholangiocarcinoma specimens from 96 patients.Results: The frequency of loss of the epithelial marker E-cadherin, and acquisition of mesenchymal markers, vimentin and N-cadherin, in intrahepatic cholangiocarcinoma was 43.8%, 37.5% and 57.3%, respectively. Altered expression of EMT markers was associated with aggressive tumor behavior, including lymph node metastasis, undifferentiated-type histology, advanced tumor stage, venous invasion, and shorter overall survival. Moreover, loss of E-cadherin was retained as an independent prognostic factor for patients with intrahepatic cholangiocarcinoma in multivariate analysis.Conclusion: Our results suggest that the EMT process is associated with tumor progression and a poor outcome in patients with intrahepatic cholangiocarcinoma, and inhibition of EMT might offer novel promising molecular targets for the treatment of affected patients.Keywords: intrahepatic cholangiocarcinoma, epithelial-mesenchymal transition, expression, prognosis, immunohistochemistry

  5. Playing it safe: Patron safety strategies and experience of violence in night-time entertainment districts.

    Science.gov (United States)

    Zhou, Jin; Droste, Nicolas; Curtis, Ashlee; Zinkiewicz, Lucy; Miller, Peter

    2018-03-01

    Incidences of violence are elevated in night-time entertainment districts. Research suggests that safety-related behavioural strategies adopted while drinking can reduce negative alcohol-related outcomes. The current study investigates the use of safety strategies and its association with experiences of violence among patrons from the general population. Patron interviews (N = 3949) were conducted in and around licenced venues in Newcastle (New South Wales) and Geelong (Victoria) during peak trading hours (Friday and Saturday, 21:00-01:00 h). Participants (mean age = 24.3, SD = 5.8; male 54.4%) were asked to report what measures, if any, they used to keep safe when drinking and whether they had been involved in a violent incident in the last 12 months. After controlling for patron demographics and location, the use of multiple (more than one) safety strategies was significantly associated with reduced odds of involvement in a violent incident (odds ratio = 0.64, 95% confidence interval 0.49-0.85, P = 0.002). Significant gender differences were observed in the number and type of safety strategies reported. Increasing the number of safety-related behaviours during drinking occasions is associated with a small but significant reduction in experiencing alcohol-related harms, such as violence. [Zhou J, Droste N, Curtis A, Zinkiewicz L, Miller P. Playing it safe: Patron safety strategies and experience of violence in night-time entertainment districts. © 2017 Australasian Professional Society on Alcohol and other Drugs.

  6. The Astronomical Instruments from the Tomb of Xiahou Zao (? - 165BCE) Revisited

    Science.gov (United States)

    Shi, Yunli

    2012-09-01

    In 1977, archaeologists unearthed a piece of lacquerware from the tomb of Xiahou Zao (?--165BCE), the 2nd Marquis of Ruyin of the Western Han dynasty (206BCE--24ACE). It has been named ``A Lacquerware Article of Unkown Name" for no one understands its function. Our analysis shows that the article is actually a gnomon for the determination of 4 major seasons in ancient Chinese calendar, viz. Spring Equinox, Summer Solstice, Autumn Equinox and Winter Solstice, and the size and function of the article coincide quite well with those of the ``Earth Gnomon-Scale" as described in the Rites of Zhou, a Confucian Classic appeared in the middle of the 2nd century BCE. This is the earliest example of its kind that we have hitherto seen in a complete form. Moreover, the "Disks with 28 Lunar Lodges" from the same tomb have caused a lasting dispute over their possible function. While some scholars believe it to be a pure astrological instrument, others guess that it was an instrument for the measurement of celestial coordinates. Our analysis shows that, with the so-called ``Supporting Frame for the Cosmic Boards" unearthed from the same tomb, the disks can actually be mounted onto the plane of the celestial equator and thus form the earliest and definitely dated example of an equatorial device for astronomical observation that still can be seen in the world.

  7. Quercetin inhibits epithelial–mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial–mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells

    Directory of Open Access Journals (Sweden)

    Yu D

    2017-09-01

    Full Text Available Dinglai Yu,1 Tingting Ye,1 Yukai Xiang,1 Zhehao Shi,1 Jie Zhang,1 Bin Lou,1 Fan Zhang,1 Bicheng Chen,1,2 Mengtao Zhou1 1Department of Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province, People’s Republic of China; 2Zhejiang Provincial Top Key Discipline in Surgery, Wenzhou Key Laboratory of Surgery, Wenzhou, Zhejiang Province, People’s Republic of China Abstract: Quercetin, a flavone, is multifaceted, having anti-oxidative, anti-inflammatory, and anticancer properties. In the present study, we explored the effects of quercetin on the epithelial–mesenchymal transition (EMT and invasion of pancreatic cancer cells and the underlying mechanisms. We noted that quercetin exerted pronounced inhibitory effects in PANC-1 and PATU-8988 cells. Moreover, quercetin inhibited EMT and decreased the secretion of matrix metalloproteinase (MMP. Meanwhile, we determined the activity of STAT3 after quercetin treatment. STAT3 phosphorylation decreased following treatment with quercetin. We also used activating agent of STAT3, IL-6, to induce an increase in cell malignancy and to observe the effects of treatment with quercetin. As expected, the EMT and MMP secretion increased with activation of the STAT3 signaling pathway, and quercetin reversed IL-6-induced EMT, invasion, and migration. Therefore, our results demonstrate that quercetin triggers inhibition of EMT, invasion, and metastasis by blocking the STAT3 signaling pathway, and thus, quercetin merits further investigation. Keywords: quercetin, EMT, MMPs, STAT3, pancreatic cancer

  8. 14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr

    Directory of Open Access Journals (Sweden)

    Sakai Keiko

    2008-04-01

    Full Text Available Abstract Background Despite continuing advances in our understanding of AIDS pathogenesis, the mechanism of CD4+ T cell depletion in HIV-1-infected individuals remains unclear. The HIV-1 Vpr accessory protein causes cell death, likely through a mechanism related to its ability to arrest cells in the G2,M phase. Recent evidence implicated the scaffold protein, 14-3-3, in Vpr cell cycle blockade. Results We found that in human T cells, 14-3-3 plays an active role in mediating Vpr-induced cell cycle arrest and reveal a dramatic increase in the amount of Cdk1, Cdc25C, and CyclinB1 bound to 14-3-3 θ during Vprv-induced G2,M arrest. By contrast, a cell-cycle-arrest-dead Vpr mutant failed to augment 14-3-3 θ association with Cdk1 and CyclinB1. Moreover, G2,M arrest caused by HIV-1 infection strongly correlated with a disruption in 14-3-3 θ binding to centrosomal proteins, Plk1 and centrin. Finally, Vpr caused elevated levels of CyclinB1, Plk1, and Cdk1 in a complex with the nuclear transport and spindle assembly protein, importin β. Conclusion Thus, our data reveal a new facet of Vpr-induced cell cycle arrest involving previously unrecognized abnormal rearrangements of multiprotein assemblies containing key cell cycle regulatory proteins. Reviewers This article was reviewed by David Kaplan, Nathaniel R. Landau and Yan Zhou.

  9. Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3

    Directory of Open Access Journals (Sweden)

    Li S

    2016-02-01

    Full Text Available Sainan Li, Yujing Xia, Kan Chen, Jingjing Li, Tong Liu, Fan Wang, Jie Lu, Yingqun Zhou, Chuanyong Guo Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China Background: Epigallocatechin-3-gallate (EGCG is the most effective compound in green tea, and possesses a wide range of beneficial effects, including anti-inflammatory, antioxidant, antiobesity, and anticancer effects. In this study, we investigated the protective effects of EGCG in concanavalin A (ConA-induced hepatitis in mice and explored the possible mechanisms involved in these effects.Methods: Balb/C mice were injected with ConA (25 mg/kg to induce acute autoimmune hepatitis, and EGCG (10 or 30 mg/kg was administered orally twice daily for 10 days before ConA injection. Serum liver enzymes, proinflammatory cytokines, and other marker proteins were determined 2, 8, and 24 hours after the ConA administration.Results: BNIP3 mediated cell apoptosis and autophagy in ConA-induced hepatitis. EGCG decreased the immunoreaction and pathological damage by reducing inflammatory factors, such as TNF-α, IL-6, IFN-γ, and IL-1β. EGCG also exhibited an antiapoptotic and antiautophagic effect by inhibiting BNIP3 via the IL-6/JAKs/STAT3 pathway.Conclusion: EGCG attenuated liver injury in ConA-induced hepatitis by downregulating IL-6/JAKs/STAT3/BNIP3-mediated apoptosis and autophagy. Keywords: concanavalin A, hepatitis, EGCG, autophagy, apoptosis, BNIP3, STAT3, JAKs, IL-6

  10. IONP-doped nanoparticles for highly effective NIR-controlled drug release and combination tumor therapy

    Directory of Open Access Journals (Sweden)

    Fu X

    2017-05-01

    Full Text Available Xudong Fu,1 Xinjun Wang,1 Shaolong Zhou,1 Yanyan Zhang2 1The Fifth Affiliated Hospital of Zhengzhou University, 2School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, People’s Republic of China Abstract: Despite advances in controlled drug delivery, drug delivery systems (DDSs with controlled activated drug release and high spatial and temporal resolution are still required. Theranostic nanomedicine is capable of diagnosis, therapy, and monitoring the delivery and distribution of drug molecules and has received growing interest. In this study, a near-infrared light-controlled “off–on” DDS with magnetic resonance imaging and magnetic targeting properties was developed using a hybrid nanoplatform (carbon nanotubes [CNTs]-iron oxide nanoparticle. Doxorubicin (DOX and distearoyl-sn-glycero-3-phosphoethanolamine-PEG were adsorbed onto CNTs-iron oxide nanoparticle, and then to avoid the unexpected drug release during circulation, 1-myristyl alcohol was used to encapsulate the CNTs–drug complex. Herein, multifunctional DOX-loaded nanoparticles (NPs with “off–on” state were developed. DOX-NPs showed an obvious “off–on” effect (temperature increase, drug release controlled by near-infrared light in vitro and in vivo. In the in vivo and in vitro studies, DOX-NPs exhibited excellent magnetic resonance imaging ability, magnetic targeting property, high biosafety, and high antitumor combined therapeutic efficacy (hyperthermia combined with chemotherapy. These results highlight the great potential of DOX-NPs in the treatment of cancer. Keywords: controlled drug release, magnetic targeting, MRI, combination therapy

  11. Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

    Science.gov (United States)

    Zhang, Liping; Rajan, Vik; Lin, Eugene; Hu, Zhaoyong; Han, H. Q.; Zhou, Xiaolan; Song, Yanping; Min, Hosung; Wang, Xiaonan; Du, Jie; Mitch, William E.

    2011-01-01

    Chronic kidney disease (CKD) and several other catabolic conditions are characterized by increased circulating inflammatory cytokines, defects in IGF-1 signaling, abnormal muscle protein metabolism, and progressive muscle atrophy. In these conditions, no reliable treatments successfully block the development of muscle atrophy. In mice with CKD, we found a 2- to 3-fold increase in myostatin expression in muscle. Its pharmacological inhibition by subcutaneous injections of an anti-myostatin peptibody into CKD mice (IC50 ∼1.2 nM) reversed the loss of body weight (≈5–7% increase in body mass) and muscle mass (∼10% increase in muscle mass) and suppressed circulating inflammatory cytokines vs. results from CKD mice injected with PBS. Pharmacological myostatin inhibition also decreased the rate of protein degradation (16.38±1.29%; Pmyostatin expression via a NF-κB-dependent pathway, whereas muscle cells exposed to myostatin stimulated IL-6 production via p38 MAPK and MEK1 pathways. Because IL-6 stimulates muscle protein breakdown, we conclude that CKD increases myostatin through cytokine-activated pathways, leading to muscle atrophy. Myostatin antagonism might become a therapeutic strategy for improving muscle growth in CKD and other conditions with similar characteristics.—Zhang, L., Rajan, V., Lin, E., Hu, Z., Han, H.Q., Zhou, X., Song, Y., Min, H., Wang, X., Du, J., Mitch, W. E. Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease. PMID:21282204

  12. Early diagnostic potential of APC hypermethylation in esophageal cancer

    Directory of Open Access Journals (Sweden)

    Wang B

    2018-02-01

    Full Text Available Bujiang Wang,1 Haojun Song,1 Haizhong Jiang,1 Yangbo Fu,1 Xiaoyun Ding,1 Chongchang Zhou2 1Department of Gastroenterology, Laboratory of Digestive Diseases, Ningbo First Hospital, Ningbo, 2Department of Otorhinolaryngology Head and Neck Surgery, Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of China Background: The hypermethylation of APC gene is observed in various cancers, including esophageal cancer (EC. However, the association between APC methylation and the initiation and progression of EC is poorly understood. Purpose and methods: The current study systematically reviewed studies on abnormal methylation of APC in EC and quantitatively synthesized 18 studies by meta-analysis involving 1008 ECs, 570 Barrett’s esophagus (BE, and 782 controls. Results: Our results showed higher methylation of APC in EC (OR = 23.33, P < 0.001 and BE (OR = 9.34, P < 0.001 than in normal controls. Whereas APC methylation in EC was similar to that in BE (P = 0.052, it was not associated with tumor stage (P = 0.204. Additionally, APC methylation was not significantly associated with overall survival (OS and relapse-free survival (RFS in patients with EC. The performance of APC methylation for the detection of EC and BE achieved areas under the receiver operating characteristic curves of 0.94 and 0.88, respectively. Conclusion: Our results imply that APC methylation detection is a potential diagnostic biomarker for EC and BE. Keywords: esophageal cancer, Barrett’s esophagus, methylation, APC

  13. Carbon nanotube-incorporated collagen hydrogels improve cell alignment and the performance of cardiac constructs

    Directory of Open Access Journals (Sweden)

    Sun HY

    2017-04-01

    Full Text Available Hongyu Sun,* Jing Zhou,* Zhu Huang,* Linlin Qu,* Ning Lin,* Chengxiao Liang, Ruiwu Dai, Lijun Tang, Fuzhou Tian General Surgery Center, Chengdu Military General Hospital, Chengdu, China *These authors contributed equally to this work Abstract: Carbon nanotubes (CNTs provide an essential 2-D microenvironment for cardiomyocyte growth and function. However, it remains to be elucidated whether CNT nanostructures can promote cell–cell integrity and facilitate the formation of functional tissues in 3-D hydrogels. Here, single-walled CNTs were incorporated into collagen hydrogels to fabricate (CNT/Col hydrogels, which improved mechanical and electrical properties. The incorporation of CNTs (up to 1 wt% exhibited no toxicity to cardiomyocytes and enhanced cell adhesion and elongation. Through the use of immunohistochemical staining, transmission electron microscopy, and intracellular calcium-transient measurement, the incorporation of CNTs was found to improve cell alignment and assembly remarkably, which led to the formation of engineered cardiac tissues with stronger contraction potential. Importantly, cardiac tissues based on CNT/Col hydrogels were noted to have better functionality. Collectively, the incorporation of CNTs into the Col hydrogels improved cell alignment and the performance of cardiac constructs. Our study suggests that CNT/Col hydrogels offer a promising tissue scaffold for cardiac constructs, and might serve as injectable biomaterials to deliver cell or drug molecules for cardiac regeneration following myocardial infarction in the near future. Keywords: carbon nanotubes, collagen hydrogel, cardiac constructs, cell alignment, tissue functionality

  14. Pharmaceutical interventions by collaboration between staff pharmacists and clinical pharmacists and implementation of Joint Commission International Accreditation Standards on medication use may optimize pharmacotherapy in geriatric patients

    Directory of Open Access Journals (Sweden)

    Chen M

    2016-11-01

    Full Text Available Meng Chen, Quan Zhou Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of ChinaWe read with great interest the prospective study by Cortejoso et al,1 which describes the characteristics of pharmaceutical interventions in two geriatric wards (orthogeriatric ward and geriatric day unit of a general teaching hospital. We strongly agree with their finding that shows the importance of clinical pharmacist involvement in the optimization of pharmacotherapy in elderly patients. Furthermore, we especially appreciate their new and interesting findings that the clinical pharmacist was more frequently requested by physicians and nurses for information about the pharmacotherapy of the patients on the geriatric day unit, compared with the orthogeriatric ward at admission and discharge (5.7% vs 1.2% and 1.7%, respectively, P<0.05, and that the pharmacist asked for more confirmation of the physician orders on the geriatric day unit rather than the orthogeriatric ward (19.8% vs 1.8% and 15.7% at admission and discharge, respectively, P<0.05. We are from a Joint Commission International (JCI-accredited academic medical center hospital with 3200 beds in China. Safe medication management and use are pivotal to patient safety and quality of care on which the state-of-the-art standards of the Joint Commission focus. We would like to share our perspectives in the following paragraphs.View original paper by Cortejoso and colleagues. 

  15. The development of Shevchenko’s studies in the PRC in the 20th – at the beginning of the 21st century

    Directory of Open Access Journals (Sweden)

    Diachenko, O. V.

    2015-07-01

    Full Text Available The article discusses the development of Shevchenko’s Studies in China from the early twentieth century to the present day. The author established that the first publication of Ukrainian poet’s poems in China were done in the 1920s. Originally poems by Taras Shevchenko were published in Ukrainian editions of our emigration in Harbin and Shanghai. Publications by Kobzar’s poems in Chinese began in the late 1920s – early 1930s. First article about Ukrainian writer and his poem «Oh, three wide ways» was published by a Chinese writer and literary critic Zhou Tszozhen. Overall, this article is devoted to works in the field of Shevchenko’s Studies by Chinese literary critics, including Lu Xun, Xiao Sanya Chen Yuan, Sun Wei, Meng Hai, Zhang Tesyan and others. The most prominent Chinese expert in Shevchenko’s Studies today is a connoisseur of Slavic literature, translator, literary critic Professor Ge Baotsyuan, who first translated the poems by Shevchenko from to Ukrainian Chinese (his precursors carried translations of Kobzar’s poems mainly from Russian, German and English. It is also found that studying of life and works of Taras Shevchenko in China is included into many university courses in foreign literature, «Testament» is studied in Chinese schools. In 2008 the monument to Kobzar was opened. A collection of Kobzar’s poems in Chinese which contains 139 texts was published in 2016.

  16. Fog prediction using the modified asymptotic liquid water content vertical distribution formulation with the Weather Research and Forecasting model

    Science.gov (United States)

    Kim, E.; Lee, S.; Kim, J.; Chae, D.

    2017-12-01

    Fog forecasts have difficulty in forecasting due to temporal and spatial resolution problems, high numerical computations, complicated mechanisms related to turbulence in order to analyze the fog in the model, and a lack of appropriate fog physical processes. Conventional fog prediction is based on the surface visibility threshold "fog diagnosis method is based on the fog related variables near the surface, such as visibility, low stratus, relative humidity and wind speed but this method only predicts fog occurrence not fog intensity. To improve this, a new fog diagnostic scheme, based on an asymptotic analytical study of radiation fog (Zhou and Ferrier 2008, ZF08) is to increase the accuracy of fog prediction by calculating the vertical LWC considering cooling, turbulence and droplet settling, visibility, surface relative humidity and low stratus. In this study, we intend to improve fog prediction through the Weather Research and Forecasting (WRF) model using high-resolution data. Although the prediction accuracy can be improved by combining the WRF Planetary Boundary Layer (PBL) scheme and 1 dimension (1D) model, it is necessary to increase the vertical resolution in the boundary layer to implement the fog formation and persistence mechanism in the internal boundary layer in the PBL more accurately, we'll modify the algorithm to enhance the effects of turbulence and then compare the newly predicted fog and observations to determine the accuracy of the forecast of the fog occurring on the Korean peninsula.

  17. Carrier mobility and crystal perfection of tetracene thin film FET

    International Nuclear Information System (INIS)

    Moriguchi, N.; Nishikawa, T.; Anezaki, T.; Unno, A.; Tachibana, M.; Kojima, K.

    2006-01-01

    It is well-known that the carrier mobility of an organic field effect semiconductor (FET) depended on the crystal quality and/or the crystal perfection of the organic thin films [T.W. Kelly, D.V. Muyres, P.F. Baude, T.P. Smith, T.D. Jones, Mater. Res. Soc. Symp. Proc. 771 (2003) L6.5.1; D.J. Gundlach, J.A. Nichols, L. Zhou, T.N. Jackson, Appl. Phys. Lett. 80 (2002) 2925; H.K. Lauk, M. Halik, U. Zschieschang, G. Schmid, W. Radlik, J. Appl. Phys. 92 (2002) 5259; M. Shtein, J. Mapel, J.B. Benziger, S.R. Forrest, Appl. Phys. Lett. 81 (2002) 268; D. Knipp, R.A. Street, A.R. Volkel, Appl. Phys. Lett. 82 (2003) 3907; R. Ruiz, A.C. Mayer, G.G. Malliaras, Appl. Phys. Lett. 85 (2004) 4926; R.W.I. de Boer, M.E. Gershenson, A.F. Morpurgo, V. Podzorov, Phys. Stat. Sol. A 201 (2004) 1031]. To improve the crystal quality of the thin film many efforts were made. One of the important improvements was the surface treatment of the substrate. The tetracene thin film FET (top contact structure) was fabricated using the substrate, which was coated by a spin-coating method with a 0.1% poly α-methylstyrene (AMS) solution. The crystal quality was improved by this treatment so that the carrier mobility was higher than that of non-treatment. The maximum mobility of the AMS-treated sample was obtained to be 0.12 cm 2 /V s

  18. High risk factors for severe hand, foot and mouth disease: A multicenter retrospective survey in Anhui Province China, 2008-2009

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    Jiahua Pan

    2012-01-01

    Full Text Available Objectives: This study sought to determine the high risk factors for severe hand, foot, and mouth disease (HFMD. Materials and Methods: Retrospective 229 severe HFMD cases from four hospitals in FuYang, HeFei, and BoZhou (Anhui Provincial Hospital, Fuyang City People′s Hospital, No. 2 People′s Hospital of Fuyang and Bozhou city People′s Hospital in 2008-2009 were studied, with 140 mild HFMD cases in the same area. Using univariate and multivariate logistic regression analyses, the high risk factors of HFMD were identified by comparing clinical and laboratory findings between severe cases and mild cases. Results: There was a significant difference in age, total duration of fever, rate of respiratory and heart, shake of limbs, white blood cell count, blood sugar, and CK-MB between the two groups. Univariate logistic regression analysis showed that severe cases were associated with age (<3 years, withdrawnness and lethargy, shake of limbs, tachycardia, total leukocyte count (≥17×10 9 /l, blood sugar (≥7 mmol/l, and CK-MB (≥16 mmol/l. Furthermore, age (<3 years, withdrawnness, and lethargy, shake of limbs, WBC (≥17×10 9 /l, and CK-MB (≥16 mmol/l were found to be high risk factors for severe cases after multivariate logistic regression analysis. Conclusions: Clinicians should give importance to these risk factors. Early recognition of children at risk and timely intervention is the key to reduce acute mortality and morbidity.

  19. Paeoniflorin prevents hypoxia-induced epithelial–mesenchymal transition in human breast cancer cells

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    Zhou Z

    2016-04-01

    Full Text Available Zhenyu Zhou,1,* Shunchang Wang,1,* Caijuan Song,2 Zhuang Hu11Department of Thyroid and Breast, Huaihe Hospital, Henan University, Kaifeng, 2Department of Immunization Program, Zhengzhou Center for Disease Control and Prevention, Zhengzhou, People’s Republic of China*These authors contributed equally to this workAbstract: Paeoniflorin (PF is a monoterpene glycoside extracted from the root of Paeonia lactiflora Pall. Previous studies have demonstrated that PF inhibits the growth, invasion, and metastasis of tumors in vivo and in vitro. However, the effect of PF on hypoxia-induced epithelial–mesenchymal transition (EMT in breast cancer cells remains unknown. Therefore, the objective of this study was to investigate the effect of PF on hypoxia-induced EMT in breast cancer cells, as well as characterize the underlying mechanism. The results presented in this study demonstrate that PF blocks the migration and invasion of breast cancer cells by repressing EMT under hypoxic conditions. PF also significantly attenuated the hypoxia-induced increase in HIF-1α level. Furthermore, PF prevented hypoxia-induced expression of phosphorylated PI3K and Akt in MDA-MB-231 cells. In conclusion, PF prevented hypoxia-induced EMT in breast cancer cells by inhibiting HIF-1α expression via modulation of PI3K/Akt signaling pathway. This finding provides evidence that PF can serve as a therapeutic agent for the treatment of breast cancer.Keywords: paeoniflorin, breast cancer, hypoxia, epithelial–mesenchymal transition, PI3K/Akt signaling pathway

  20. Therapy effects of gold nanorods on the CNE-1 nasopharyngeal carcinoma cell line

    Directory of Open Access Journals (Sweden)

    Shao J

    2012-10-01

    Full Text Available Jinyan Shao,1 Jianguo Tang,1 Jian Ji,2 Wenbo Zhou21Department of Otolaryngology, Head and Neck Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 2Department of Polymer Science, Ministry of Education Key Laboratory of Macromolecule Synthesis and Functionalization, Zhejiang University, Hangzhou, People's Republic of ChinaAbstract: The use of nanocarriers to deliver drugs to tumor tissue is one of the most important strategies in cancer therapeutics. Recently, gold nanorods (GNRs have begun to be used in cancer therapy because of their unique properties. The purpose of this study was to show the potential that GNRs have against human nasopharyngeal carcinoma CNE-1 cells, using near-infrared (NIR laser light. Transmission electron microscopic and ultraviolet-visible spectroscopic investigations confirmed the efficient uptake of the GNRs by CNE-1 and human rhinal epithelia cells. The in vitro NIR photothermal therapy for the CNE-1 and rhinal epithelia cells was designed in three groups: (1 control, (2 laser alone, and (3 GNRs with laser. Fluorescence microscopy images indicated that, at some GNR concentrations and some intensities of NIR laser, GNRs with laser therapy could induce cell death for CNE-1 cells while keeping the rhinal epithelia cells healthy. Therefore, the results of this study suggest that using GNRs with NIR laser therapy can selectively destruct CNE-1 cells while having no effect on normal (rhinal epithelia cells.Keywords: photothermal therapy, near-infrared laser, rhinal epithelia cells, cell uptake