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Sample records for bhas methodological approach

  1. Bhas 42 cell transformation activity of cigarette smoke condensate is modulated by selenium and arsenic.

    Science.gov (United States)

    Han, Sung Gu; Pant, Kamala; Bruce, Shannon W; Gairola, C Gary

    2016-04-01

    Cigarette smoking remains a major health risk worldwide. Development of newer tobacco products requires the use of quantitative toxicological assays. Recently, v-Ha-ras transfected BALB/c3T3 (Bhas 42) cell transformation assay was established that simulates the two-stage animal tumorigenesis model and measures tumor initiating and promoting activities of chemicals. The present study was performed to assess the feasibility of using this Bhas 42 cell transformation assay to determine the initiation and promotion activities of cigarette smoke condensate (CSC) and its water soluble fraction. Further, the modulating effects of selenium and arsenic on cigarette smoke-induced cell transformation were investigated. Dimethyl sulfoxide (DMSO) and water extracts of CSC (CSC-D and CSC-W, respectively) were tested at concentrations of 2.5-40 µg mL(-1) in the initiation or promotion assay formats. Initiation protocol of the Bhas 42 assay showed a 3.5-fold increase in transformed foci at 40 µg mL(-1) of CSC-D but not CSC-W. The promotion phase of the assay yielded a robust dose response with CSC-D (2.5-40 µg mL(-1)) and CSC-W (20-40 µg mL(-1)). Preincubation of cells with selenium (100 nM) significantly reduced CSC-induced increase in cell transformation in initiation assay. Co-treatment of cells with a sub-toxic dose of arsenic significantly enhanced cell transformation activity of CSC-D in promotion assay. The results suggest a presence of both water soluble and insoluble tumor promoters in CSC, a role of oxidative stress in CSC-induced cell transformation, and usefulness of Bhas 42 cell transformation assay in comparing tobacco product toxicities and in studying the mechanisms of tobacco carcinogenesis. © 2016 Wiley Periodicals, Inc.

  2. Approaches and methodologies for mobile software engineering

    Directory of Open Access Journals (Sweden)

    Serena Pastore

    2015-09-01

    Full Text Available The development of software for mobile devices takes place in a dynamic environment where constraints, technologies and user needs change very frequently requiring enhanced approaches and methodologies in software engineering essential to deal with the concept of bring your own device (BYOD. Mobile apps are developed for various purposes in different categories. This paper discusses about the challenges that affect mobile software engineering, specifically for a science educational and outreach aim as regards technologies, approaches and methodologies that could be applied to unlock the full potential of mobility. In particular, it analyzes the main challenges to development in this field, such as dealing with enhanced connectivity and networking protocols (e.g., from Bluetooth Low Energy, IEEE 802.15.4-based protocols and new Wi-Fi versions and the fragmented ecosystem of mobile platforms. Moreover, it addresses the possible application of specific development methodologies such as Agile software methods.

  3. Methodological triangulation: an approach to understanding data.

    Science.gov (United States)

    Bekhet, Abir K; Zauszniewski, Jaclene A

    2012-01-01

    To describe the use of methodological triangulation in a study of how people who had moved to retirement communities were adjusting. Methodological triangulation involves using more than one kind of method to study a phenomenon. It has been found to be beneficial in providing confirmation of findings, more comprehensive data, increased validity and enhanced understanding of studied phenomena. While many researchers have used this well-established technique, there are few published examples of its use. The authors used methodological triangulation in their study of people who had moved to retirement communities in Ohio, US. A blended qualitative and quantitative approach was used. The collected qualitative data complemented and clarified the quantitative findings by helping to identify common themes. Qualitative data also helped in understanding interventions for promoting 'pulling' factors and for overcoming 'pushing' factors of participants. The authors used focused research questions to reflect the research's purpose and four evaluative criteria--'truth value', 'applicability', 'consistency' and 'neutrality'--to ensure rigour. This paper provides an example of how methodological triangulation can be used in nursing research. It identifies challenges associated with methodological triangulation, recommends strategies for overcoming them, provides a rationale for using triangulation and explains how to maintain rigour. Methodological triangulation can be used to enhance the analysis and the interpretation of findings. As data are drawn from multiple sources, it broadens the researcher's insight into the different issues underlying the phenomena being studied.

  4. Theoretical and methodological approaches in discourse analysis.

    Science.gov (United States)

    Stevenson, Chris

    2004-10-01

    Discourse analysis (DA) embodies two main approaches: Foucauldian DA and radical social constructionist DA. Both are underpinned by social constructionism to a lesser or greater extent. Social constructionism has contested areas in relation to power, embodiment, and materialism, although Foucauldian DA does focus on the issue of power. Embodiment and materialism may be especially relevant for researchers of nursing where the physical body is prominent. However, the contested nature of social constructionism allows a fusion of theoretical and methodological approaches tailored to a specific research interest. In this paper, Chris Stevenson suggests a frame- work for working out and declaring the DA approach to be taken in relation to a research area, as well as to aid anticipating methodological critique. Method, validity, reliability and scholarship are discussed from within a discourse analytic frame of reference.

  5. Comparative tumor promotion assessment of e-cigarette and cigarettes using the in vitro Bhas 42 cell transformation assay.

    Science.gov (United States)

    Breheny, Damien; Oke, Oluwatobiloba; Pant, Kamala; Gaça, Marianna

    2017-05-01

    In vitro cell transformation assays (CTA) are used to assess the carcinogenic potential of chemicals and complex mixtures and can detect nongenotoxic as well as genotoxic carcinogens. The Bhas 42 CTA has been developed with both initiation and promotion protocols to distinguish between these two carcinogen classes. Cigarette smoke is known to be carcinogenic and is positive in in vitro genotoxicity assays. Cigarette smoke also contains nongenotoxic carcinogens and is a tumour promoter and cocarcinogen in vivo. We have combined a suite of in vitro assays to compare the relative biological effects of new categories of tobacco and nicotine products with traditional cigarettes. The Bhas promotion assay has been included in this test battery to provide an in vitro surrogate for detecting tumor promoters. The activity of an electronic cigarette (e-cigarette; Vype ePen) was compared to that of a reference cigarette (3R4F) in the promotion assay, using total particulate matter (TPM)/aerosol collected matter (ACM) and aqueous extracts (AqE) of product aerosol emissions. 3R4F TPM was positive in this assay at concentrations ≥6 µg/mL, while e-cigarette ACM did not have any promoter activity. AqE was found to be a lesssuitable test matrix in this assay due to high cytotoxicity. This is the first study to use the Bhas assay to compare tobacco and nicotine products and demonstrates the potential for its future application as part of a product assessment framework. These data add to growing evidence suggesting that e-cigarettes may provide a safer alternative to traditional cigarettes. Environ. Mol. Mutagen. 58:190-198, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  6. Methodological approaches in the research of organizational culture

    Directory of Open Access Journals (Sweden)

    Janićijević Nebojša

    2011-01-01

    Full Text Available In the thirty-years-long research of organizational culture, two mutually opposed methodological approaches have emerged: objectivistic quantitative and subjectivistic-qualitative. These two approaches are based on opposite ontological and epistemological assumptions: they include different types of research, and use opposite, quantitative vs. qualitative, methods of research. Each of the methodological approaches has its advantages and disadvantages. For this reason a hybrid approach emerges as a legitimate choice in organizational culture research methodology. It combines elements of both subjectivistic and objectivistic methodological approaches, according to the goals, content, and context of the research and preferences of the researcher himself/herself. Since it is possible to combine the two principal methodological approaches in various ways, there are several possible hybrid methodologies in organizational culture research. After the review of objectivistic quantitative and subjectivistic-qualitative methodological approaches, one of possible hybrid approaches in the research of organizational culture is presented in this paper.

  7. A Methodological Approach to Quantifying Plyometric Intensity.

    Science.gov (United States)

    Jarvis, Mark M; Graham-Smith, Phil; Comfort, Paul

    2016-09-01

    Jarvis, MM, Graham-Smith, P, and Comfort, P. A Methodological approach to quantifying plyometric intensity. J Strength Cond Res 30(9): 2522-2532, 2016-In contrast to other methods of training, the quantification of plyometric exercise intensity is poorly defined. The purpose of this study was to evaluate the suitability of a range of neuromuscular and mechanical variables to describe the intensity of plyometric exercises. Seven male recreationally active subjects performed a series of 7 plyometric exercises. Neuromuscular activity was measured using surface electromyography (SEMG) at vastus lateralis (VL) and biceps femoris (BF). Surface electromyography data were divided into concentric (CON) and eccentric (ECC) phases of movement. Mechanical output was measured by ground reaction forces and processed to provide peak impact ground reaction force (PF), peak eccentric power (PEP), and impulse (IMP). Statistical analysis was conducted to assess the reliability intraclass correlation coefficient and sensitivity smallest detectable difference of all variables. Mean values of SEMG demonstrate high reliability (r ≥ 0.82), excluding ECC VL during a 40-cm drop jump (r = 0.74). PF, PEP, and IMP demonstrated high reliability (r ≥ 0.85). Statistical power for force variables was excellent (power = 1.0), and good for SEMG (power ≥0.86) excluding CON BF (power = 0.57). There was no significant difference (p > 0.05) in CON SEMG between exercises. Eccentric phase SEMG only distinguished between exercises involving a landing and those that did not (percentage of maximal voluntary isometric contraction [%MVIC] = no landing -65 ± 5, landing -140 ± 8). Peak eccentric power, PF, and IMP all distinguished between exercises. In conclusion, CON neuromuscular activity does not appear to vary when intent is maximal, whereas ECC activity is dependent on the presence of a landing. Force characteristics provide a reliable and sensitive measure enabling precise description of intensity

  8. Methodological Individualism and the Organizational Capabilities Approach

    DEFF Research Database (Denmark)

    Felin, Teppo; Foss, Nicolai Juul

    2004-01-01

    critical individual-levelconsiderations, including individual action and heterogeneity. In this note we do not denyor reject the notion of routines or capabilities per se, but rather call for an increasedemphasis on how these collective structures originate and change as a result of individualactions.......Key words: Organizational capabilities, methodological individualism, philosophy ofsocial science...

  9. Methodological Individualism and the Organizational Capabilities Approach

    DEFF Research Database (Denmark)

    Felin, Teppo; Foss, Nicolai Juul

    2004-01-01

    critical individual-levelconsiderations, including individual action and heterogeneity. In this note we do not denyor reject the notion of routines or capabilities per se, but rather call for an increasedemphasis on how these collective structures originate and change as a result of individualactions.......Key words: Organizational capabilities, methodological individualism, philosophy ofsocial science...

  10. Toward a Post-Multicase Methodological Approach

    Science.gov (United States)

    Le Blanc, Amana Marie

    2016-01-01

    This article posits the use of adapted multicase methodology as appropriate to the exploration of participant cases and context that are fragmented, fluid, and interconnected artefacts of hypermediated postmodern experiences. This paper attempts to deconstruct conventional interpretations of "case" and "context," in an effort…

  11. Ethnologic Linguodidactic Approach as a Methodological Support for Multilingual Education

    Directory of Open Access Journals (Sweden)

    Bakhytgul A. Zhetpisbayeva

    2012-11-01

    Full Text Available The present work investigates the issues of methodological support for the process of multilingual education, where ethnologic linguodidactic approach is being considered and substantiated. There is being discovered the essence of the methodological approach based on identifying the relation of this concept to the methodological principle. It has been shown that the ethnologic linguodidactic approach is a systematic combination of fundamental principles, specialized methods and specified tools serving to distinguish the issues of multilingual education, to define a strategy to resolve them under specific sociolinguistic conditions of multilingual and multicultural community.

  12. Methodological Approach for Modeling of Multienzyme in-pot Processes

    DEFF Research Database (Denmark)

    Andrade Santacoloma, Paloma de Gracia; Roman Martinez, Alicia; Sin, Gürkan;

    2011-01-01

    This paper presents a methodological approach for modeling multi-enzyme in-pot processes. The methodology is exemplified stepwise through the bi-enzymatic production of N-acetyl-D-neuraminic acid (Neu5Ac) from N-acetyl-D-glucosamine (GlcNAc). In this case study, sensitivity analysis is also used...

  13. Intelligence for embedded systems a methodological approach

    CERN Document Server

    Alippi, Cesare

    2014-01-01

    Addressing current issues of which any engineer or computer scientist should be aware, this monograph is a response to the need to adopt a new computational paradigm as the methodological basis for designing pervasive embedded systems with sensor capabilities. The requirements of this paradigm are to control complexity, to limit cost and energy consumption, and to provide adaptation and cognition abilities allowing the embedded system to interact proactively with the real world. The quest for such intelligence requires the formalization of a new generation of intelligent systems able to exploit advances in digital architectures and in sensing technologies. The book sheds light on the theory behind intelligence for embedded systems with specific focus on: ·        robustness (the robustness of a computational flow and its evaluation); ·        intelligence (how to mimic the adaptation and cognition abilities of the human brain), ·        the capacity to learn in non-stationary and evolv...

  14. Crosslinking: methodological approaches and application in ophthalmology

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    I. B. Medvedev

    2016-01-01

    Full Text Available Crosslinking of the cornea was developed at the end of the last century and radically changed approaches to the treatment of progressive corneal ectasia. To achieve the strengthening of the corneal tissue irradiation with ultraviolet light And is combined with the use of Riboflavin. Riboflavin plays a role of a photosensitizer in the process of photopolymerization and ultraviolet irradiation increases the formation of inter — and intrafibrillary covalent bonds. Standard Protocol operation involves the scarification of epithelium, a 30‑minute application of 0.1 % solution of Riboflavin with subsequent 30 min. irradiation with ultraviolet light with A wavelength of 370 nm and 3 mW / cm2. The lack of effect of routine procedures is defined as the increase in refractive power of the cornea by 1 Diopter. after treatment and observed in 8.1‑33.3 % of cases. A relatively frequent complication of the standard procedure of crosslinking (10‑90 % is corneal haze. A number of cases of infectious keratitis, including bacterial, protozoan and fungal forms is registered. Rare complications after standard procedure of crosslinking are diffuse lamellar keratitis, melting corneal and endothelial-epithelial dystrophy. After instillation of Riboflavin its diffusion in the corneal stroma is limited by a dense contacts between epithelial cells, resulting in crosslinking often resort to preliminary scarification of epithelium. However, this manipulation is the cause of the complications of crosslinking, as intra — and postoperative pain, infectious keratitis and lethargic regeneration of the epithelium. The permeability of the epithelium for Riboflavin can be enhanced in several ways, for example, modifying physico-chemical properties of Riboflavin molecules or increasing the permeability of the epithelium, for example, by instillation of a 40 % strength solution of glucose. It was shown that the conducting electrophoresis with Riboflavin for

  15. Evaluation of Slum Upgrading Programs: Literature Review and Methodological Approaches

    OpenAIRE

    José Brakarz; Laura Jaitman

    2013-01-01

    This technical note analyzes the methodologies used to evaluate neighborhood upgrading programs, describes their results, and suggests approaches for future evaluations. Local and central governments are increasingly utilizing slum or neighborhood upgrading programs to deal with the multiple problems of urban poverty. These programs employ a methodology of integral interventions, combining of both infrastructure works and social services targeted to specific neighborhoods. Due to this variety...

  16. Spanish methodological approach for biosphere assessment of radioactive waste disposal.

    Science.gov (United States)

    Agüero, A; Pinedo, P; Cancio, D; Simón, I; Moraleda, M; Pérez-Sánchez, D; Trueba, C

    2007-10-01

    The development of radioactive waste disposal facilities requires implementation of measures that will afford protection of human health and the environment over a specific temporal frame that depends on the characteristics of the wastes. The repository design is based on a multi-barrier system: (i) the near-field or engineered barrier, (ii) far-field or geological barrier and (iii) the biosphere system. Here, the focus is on the analysis of this last system, the biosphere. A description is provided of conceptual developments, methodological aspects and software tools used to develop the Biosphere Assessment Methodology in the context of high-level waste (HLW) disposal facilities in Spain. This methodology is based on the BIOMASS "Reference Biospheres Methodology" and provides a logical and systematic approach with supplementary documentation that helps to support the decisions necessary for model development. It follows a five-stage approach, such that a coherent biosphere system description and the corresponding conceptual, mathematical and numerical models can be built. A discussion on the improvements implemented through application of the methodology to case studies in international and national projects is included. Some facets of this methodological approach still require further consideration, principally an enhanced integration of climatology, geography and ecology into models considering evolution of the environment, some aspects of the interface between the geosphere and biosphere, and an accurate quantification of environmental change processes and rates.

  17. A methodological approach to designing sewer system control

    DEFF Research Database (Denmark)

    Mollerup, Ane Loft

    for this thesis was therefore the wish for a methodological approach to sewer system control design. Using a case study the following research hypothesis was tested in this thesis: Using classical and modern control theory, a methodological approach can be derived for designing sewer system control. This can aid...... urban drainage planner and other professionals in the planning phase of sewer system con-trol design and effectively contribute to find novel control solution. It was investigated if the established methodology used in classic control the-ory for process control design can be applied meaningfully....... This was not unexpected, since the true potential of having optimisation arises, when a system has many control loops with limit-ing constraints and/or changing prioritisation between them. The results showed that for small sewer systems, where the complexity is limited, it is not necessarily the best option to implement...

  18. Evolving Grounded Theory Methodology: towards a discursive approach.

    Science.gov (United States)

    McCreaddie, May; Payne, Sheila

    2010-06-01

    Grounded Theory Methodology (GTM) is a widely cited research approach based upon symbolic interaction with a focus on interaction, action and processes. Relatively recently, Discursive Psychology; a language-based interaction research approach also based on symbolic interaction, emerged. At present Discursive Psychology is principally cited in the social sciences literature. Given Discursive Psychology's symbolic interaction foundations, what relevance does this approach have for evolving GTM? A number of methodological challenges were posed by a study looking at humour in Clinical Nurse Specialist-patient interactions. This paper will use the phenomenon of spontaneous humour in healthcare interactions to illustrate the potential for a new form of GTM drawing on discursive approaches; Discursive GTM. First, the challenges presented by a study looking at spontaneous humour in Clinical Nurse Specialist-patient interactions are presented. Second, the research approach adopted to meet these challenges - Discursive GTM (DGTM) - is explicated and the results of the study are outlined. Third, the different GTM approaches and Discursive Psychology are compared and contrasted in relation to the DGTM approach adopted. Finally, the challenges and tensions of using DGTM as well as the opportunities afforded by the use of naturally occurring data are reviewed. The authors contend that a DGTM approach may be appropriate in analyzing certain phenomena. In particular, we highlight the potential contribution of naturally occurring data as an adjunct to researcher-elicited data. Thus, when exploring particular phenomena, a DGTM approach may address the potentially under-developed symbolic interaction tenet of language.

  19. A theoretical and methodological approach of leadership in organizations

    Directory of Open Access Journals (Sweden)

    María Laura Lupano Perugini

    2015-09-01

    Full Text Available The present work has the objective to offer a theoretical-methodological approximation respect of the leadership’s phenomenon. By virtue of the fact that such phenomenon is understood as a complex and multiderminated construct, we will approach the different theoretical schools which have tried to explain it. Also, it is attempted to answer the question about the possibility to evaluate the mentioned construct. To answer this interrogation we will present the different methodologies employed in scientific research and their possible advantages and limitations of their application to the leadership’s evaluation. 

  20. Methodology Approaches Regarding Classic versus Mobile Enterprise Application Development

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    Vasile-Daniel PAVALOAIA

    2013-01-01

    Full Text Available In the nowadays enterprise computerized context, there is a trend that shifts the business ap-plications to the new mobile environments. In the light of this information, it is highly important to be knowledgeable about the software development methodologies available in order to make the right choice when it comes to developing a mobile application. The current research aims to presenting the methodological approaches regarding the development cycle of classic enterprise software versus mobile apps. In the first part of the paper a brief literature review regarding the mobile apps is made, for the purpose of justifying the current research theme. The most consistent part of the article puts face-to-face the “classical” and the new development methodologies adapted to the requirements of the new mobile environment trends. The paper also presents the challenges and limitations of mobile applications as well as few of the future trends in the researched domain.

  1. Apprehending ganglioside diversity: a comprehensive methodological approach[S

    Science.gov (United States)

    Masson, Elodie A. Y.; Sibille, Estelle; Martine, Lucy; Chaux-Picquet, Fanny; Bretillon, Lionel; Berdeaux, Olivier

    2015-01-01

    Gangliosides (GGs) make a wide family of glycosphingolipids ubiquitously expressed in mammalian tissues and particularly abundant in the brain and nervous system. They exhibit a huge diversity due to structural variations in both their oligosaccharidic chain and ceramide moiety, which represent a real analytical challenge. Since their discovery in the 1940s, methods have persistently improved until the emergence of LC/MS, which offers a high level of specificity and sensitivity and is suitable with high-throughput profiling studies. We describe here a comprehensive approach relying on various techniques and aiming at fully characterizing GGs in biological samples. First, total GG content was determined by a biochemical assay. Second, GG class composition was assessed by high-performance thin-layer chromatography followed by colorimetric revelation. Then, ceramide types of GG classes were identified, and their relative quantification was performed thanks to the development of a powerful and reliable LC/MS method. Finally, ceramides were structurally characterized, and minor and less common GG classes were identified using high-resolution MS. These methods were applied to the rat retina to provide an exhaustive description of its GG composition, giving the base for a better understanding of the precise roles of GGs in this tissue. PMID:26142958

  2. Production systems design : a product oriented approach and methodology

    OpenAIRE

    2008-01-01

    Production systems design is critical to achieving manufacturing performance and objectives. Although generic approaches to this design are available they may not be able to objectively address specific manufacturing configurations. Here it is argued that product oriented manufacturing (POM) organization offers advantages in relation to the function oriented one. Based on this, a methodology specially addressing POM systems design, and prototype of a Computer Aided Design Syste...

  3. Life cycle methodology for copper : allocation and recycling approaches

    Energy Technology Data Exchange (ETDEWEB)

    Gobling-Reisemann, S. [Bremen Univ., Bremen (Germany). Faculty of Production Engineering; Tikana, L.; Sievers, H.; Klassert, A. [Deutsches Kupferinstitut, Dusseldorf (Germany). Life Cycle Centre

    2007-07-01

    This paper provided an overview of different methodologies available for recycling and assessing the life cycles of copper ores. Approaches towards allocation in life cycle assessments (LCA) included detailed modelling; system expansion; physical allocation; economic allocation; and subsequent-use allocation. Approaches towards recycling included system expansion, cut-off approaches, open loop approach; value corrected substitution; and the cascade approach. Sulphuric acid and steam are produced as by-products during copper production, and most copper ores contain molybdenum, gold, silver, and nickel. The environmental impacts of copper by-products must be considered when conducting LCAs. Existing standards allow different implementation methods for recycling and allocation into metal LCAs, and the selection of a methodology can significantly influence the ecological profile of copper and copper products. Allocation is needed when processes with more than 1 function are investigated. ISO standards recommend avoiding allocation problems by using detailed system modelling. Allocation factors should be chosen that reflect the physical relationship between the functional units produced and their associated environmental burdens. Case studies were presented to demonstrate allocations of co- and byproducts and recycling in copper production. 19 refs., 2 tabs., 4 figs.

  4. Methodology for rainwater reservoir dimensioning: a probabilistic approach

    Directory of Open Access Journals (Sweden)

    Wagner Wolff

    2017-05-01

    Full Text Available The aim of this study was to propose a new methodology for reservoir rainwater dimensioning based on probabilistic modeling. Eucalyptus seedlings grown in a greenhouse were used to obtain a hypothetical water demand. Meteorological data were used to estimate the demand (evapotranspiration and offer (rainfall over the greenhouse coverage. The probability distribution of Wakeby presented the best fit for the rainfall data; therefore, a Wakeby distribution was used to model the flow-duration curve of the greenhouse coverage. For a payback period (T of 10 years of surplus water demand and water supply deficit, a reservoir with 13.60 m³ was obtained. The proposed methodology combined the simultaneous occurrence of the events to enable the scaling out of a reservoir with high safety to supply the required demand (T = 100 years and therefore enables a lower cost of deployment compared to each approach separately (T = 10 years.

  5. Methodological approaches to staff recruitment at labour market

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    V.V. Bozhkova

    2016-12-01

    Full Text Available The aim of article. The purpose of the article is to improve and formalize methodological approaches to staff recruitment at labour markets. The results of the analysis. The integral result of the study is the following. The author systematized the main problems of the staff recruitment according to the subjects of the employment process (or their place of origin: 1 on the part of the applicants: - inflated / deflated self-esteem; - incorrect understanding of their own capabilities, abilities and aptitudes; - incorrect assessment of their own physical and mental health; - incorrect formulation of expectations from the new position (inflated, deflated or inadequate; - willful false responses in the survey (in order to get a better position; - inaccurate responses in the survey (due to misunderstanding of the nature of questions; - popular or prestigious professions preference, but not those to which the applicant has more talent; - providing inaccurate personal information (false or willful; 2 on the part of employers: - wrong definition of the criteria list to be met by applicants; - inflated requirements to applicants; - the best quality choice among applicants, but not employees for teamwork; 3 on the part of Heads of Labour Markets (as well as employment agencies: - lack of adequate supervision of Labour Market specialists activity (i.e., the quality level in the staff recruitment for specific employers orders; - lack of motivation to improve the skill level of subordinates; 4 on the part of experts on recruitment: - recruitment of the best available applicants, rather than looking for the applicants who fully meet the requirements; - not precise understanding of the requirements for applicants; - the use of inappropriate methods for the applicants recruitment. Such systematization of major problems can determine the direction of management decisions aimed at improving the process of recruitment more accurately. The essential characteristics

  6. Analyzing spatial data from mouse tracker methodology: An entropic approach.

    Science.gov (United States)

    Calcagnì, Antonio; Lombardi, Luigi; Sulpizio, Simone

    2017-01-11

    Mouse tracker methodology has recently been advocated to explore the motor components of the cognitive dynamics involved in experimental tasks like categorization, decision-making, and language comprehension. This methodology relies on the analysis of computer-mouse trajectories, by evaluating whether they significantly differ in terms of direction, amplitude, and location when a given experimental factor is manipulated. In this kind of study, a descriptive geometric approach is usually adopted in the analysis of raw trajectories, where they are summarized with several measures, such as maximum-deviation and area under the curve. However, using raw trajectories to extract spatial descriptors of the movements is problematic due to the noisy and irregular nature of empirical movement paths. Moreover, other significant components of the movement, such as motor pauses, are disregarded. To overcome these drawbacks, we present a novel approach (EMOT) to analyze computer-mouse trajectories that quantifies movement features in terms of entropy while modeling trajectories as composed by fast movements and motor pauses. A dedicated entropy decomposition analysis is additionally developed for the model parameters estimation. Two real case studies from categorization tasks are finally used to test and evaluate the characteristics of the new approach.

  7. A Case Study on Methodological Approaches to Conversation Analysis

    Institute of Scientific and Technical Information of China (English)

    廉莲

    2014-01-01

    Taking a piece of social interaction as the object of the study, some basic and brief analysis on how meaning is negotiat-ed is offered from both structural and functional perspectives. The potential purpose is to provide readers with a maybe rough but clear presentation of those assorted methods used in conversation analysis. Out of the presentation is developed a possibility for language learners as well as teachers to be more aware of the differences and also the interrelations among these methodological approaches to conversation analysis, which may be of some relevance to teaching practice.

  8. METHODOLOGY OF SYSTEM APPROACHE TO SEISMIC RISK ASSESSMENT AND REDUCTION

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    A. D. Abakarov

    2016-01-01

    Full Text Available Abstract. Ensuring of urban areas seismic safety is a task which do not require delay. But it cannot be solved by separate parts. It is essential that all components of the seismic hazard must be grouped together in one problem based on the system approach. In the present paper is presented not only the main flowchart of systems approach to ensuring the territory seismic safety but also the flowcharts of components of each main unit. They cover the whole package of measures for a full assessment of territory seismic hazard, seismic risk and its reduction.The proposed methodology can be carried out for design and implementation of regional territory seismic safety programs. 

  9. Theoretical, Methodological, and Empirical Approaches to Cost Savings: A Compendium

    Energy Technology Data Exchange (ETDEWEB)

    M Weimar

    1998-12-10

    This publication summarizes and contains the original documentation for understanding why the U.S. Department of Energy's (DOE's) privatization approach provides cost savings and the different approaches that could be used in calculating cost savings for the Tank Waste Remediation System (TWRS) Phase I contract. The initial section summarizes the approaches in the different papers. The appendices are the individual source papers which have been reviewed by individuals outside of the Pacific Northwest National Laboratory and the TWRS Program. Appendix A provides a theoretical basis for and estimate of the level of savings that can be" obtained from a fixed-priced contract with performance risk maintained by the contractor. Appendix B provides the methodology for determining cost savings when comparing a fixed-priced contractor with a Management and Operations (M&O) contractor (cost-plus contractor). Appendix C summarizes the economic model used to calculate cost savings and provides hypothetical output from preliminary calculations. Appendix D provides the summary of the approach for the DOE-Richland Operations Office (RL) estimate of the M&O contractor to perform the same work as BNFL Inc. Appendix E contains information on cost growth and per metric ton of glass costs for high-level waste at two other DOE sites, West Valley and Savannah River. Appendix F addresses a risk allocation analysis of the BNFL proposal that indicates,that the current approach is still better than the alternative.

  10. Towards an Airframe Noise Prediction Methodology: Survey of Current Approaches

    Science.gov (United States)

    Farassat, Fereidoun; Casper, Jay H.

    2006-01-01

    In this paper, we present a critical survey of the current airframe noise (AFN) prediction methodologies. Four methodologies are recognized. These are the fully analytic method, CFD combined with the acoustic analogy, the semi-empirical method and fully numerical method. It is argued that for the immediate need of the aircraft industry, the semi-empirical method based on recent high quality acoustic database is the best available method. The method based on CFD and the Ffowcs William- Hawkings (FW-H) equation with penetrable data surface (FW-Hpds ) has advanced considerably and much experience has been gained in its use. However, more research is needed in the near future particularly in the area of turbulence simulation. The fully numerical method will take longer to reach maturity. Based on the current trends, it is predicted that this method will eventually develop into the method of choice. Both the turbulence simulation and propagation methods need to develop more for this method to become useful. Nonetheless, the authors propose that the method based on a combination of numerical and analytical techniques, e.g., CFD combined with FW-H equation, should also be worked on. In this effort, the current symbolic algebra software will allow more analytical approaches to be incorporated into AFN prediction methods.

  11. Implementation planning for industrial energy conservation: approach and methodology

    Energy Technology Data Exchange (ETDEWEB)

    Alston, T.G.; Falk, G.; Grogan, P.J.; Katz, D.; Tatar, J.

    1981-01-01

    Details of an industry-specific Conservation Technology Implementation Branch implementation plan is described in detail. CTIB has conducted implementation planning in the steel, pulp/paper, and agriculture/food processing industries, but in FY 1981, CTIB plans to conduct planning for the chemicals, petroleum refining, aluminum, glass, cement, and textile industries. Guidelines are presented for each contractor for each industry toward a common methodology in terms of approach, areas of analysis, assumptions, and reporting. The major parts of the CTIB plan are: an implementation study consisting of technology selection, market demand analysis, and policy analysis, and a plan consisting of a detailed description and schedule of future CTIB actions, followed by a recommended system for monitoring market results when the plan is implemented. (MCW)

  12. AN AUTOMATIC AND METHODOLOGICAL APPROACH FOR ACCESSIBLE WEB APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Lourdes Moreno

    2007-06-01

    Full Text Available Semantic Web approaches try to get the interoperability and communication among technologies and organizations. Nevertheless, sometimes it is forgotten that the Web must be useful for every user, consequently it is necessary to include tools and techniques doing Semantic Web be accessible. Accessibility and usability are two usually joined concepts widely used in web application development, however their meaning are different. Usability means the way to make easy the use but accessibility is referred to the access possibility. For the first one, there are many well proved approaches in real cases. However, accessibility field requires a deeper research that will make feasible the access to disable people and also the access to novel non-disable people due to the cost to automate and maintain accessible applications. In this paper, we propose one architecture to achieve the accessibility in web-environments dealing with the WAI accessibility standard and the Universal Design paradigm. This architecture tries to control the accessibility in web applications development life-cycle following a methodology starting from a semantic conceptual model and leans on description languages and controlled vocabularies.

  13. Methodological Approaches to Locating Outlets of the Franchise Retail Network

    Directory of Open Access Journals (Sweden)

    Grygorenko Tetyana M.

    2016-08-01

    Full Text Available Methodical approaches to selecting strategic areas of managing the future location of franchise retail network outlets are presented. The main stages in the assessment of strategic areas of managing the future location of franchise retail network outlets have been determined and the evaluation criteria have been suggested. Since such selection requires consideration of a variety of indicators and directions of the assessment, the author proposes a scale of evaluation, which allows generalizing and organizing the research data and calculations of the previous stages of the analysis. The most important criteria and sequence of the selection of the potential franchisees for the franchise retail network have been identified, the technique for their evaluation has been proposed. The use of the suggested methodological approaches will allow the franchiser making sound decisions on the selection of potential target markets, minimizing expenditures of time and efforts on the selection of franchisees and hence optimizing the process of development of the franchise retail network, which will contribute to the formation of its structure.

  14. An integrated approach of composting methodologies for solid waste management

    Directory of Open Access Journals (Sweden)

    K. Kumaresan

    2016-03-01

    Full Text Available Organic fraction of solid waste, which upon degradation produces foul smell and generates pathogens, if not properly managed. Composting is not a method of waste disposal but it is a method of waste recycling and used for agricultural purposes. An integrated approach of composting methodology was tested for municipal solid waste management. Solid waste first was composted and after 22 days, was further processed by vermicomposting. Samples were routinely taken for analysis of carbon, nitrogen, moisture content, pH and temperature to determine the quality of composting. Decrease in moisture content to 32.1 %, relative decrease in carbon and nitrogen content were also observed. Among the different types of treatment, municipal solid waste + activated sludge integration showed promising results, followed by vermicomposting municipal solid waste + activated sludge combination, compared to the combinations of dried activated sludge, municipal solid waste + activated sludge semisolid and municipal solid waste + sewage water. Thus, windrow composting followed by vermicomposting gave a better result than other methods. Thus this method would serve as a potential alternative for solid waste management.

  15. Theoretical Aspects and Methodological Approaches to Sales Services Quality Assessment

    Directory of Open Access Journals (Sweden)

    Tarasova EE

    2015-11-01

    Full Text Available The article defines trade service quality and proposes an object-oriented approach for its essence interpretation, according to which such components as product offering and goods quality, service forms and goods selling methods, merchandising, services and staff are singled out; a model of managing retail outlets trading service, which covers levels of strategic, tactical and operational management and is aimed at ensuring customers’ perception expectations, achieving sustainable competitive positions and increasing customers’ loyalty is worked out; a methodology of trade services quality estimation that allows to carry out a comparative assessment of cooperative retailing both in terms of general indicators and their individual components, regulate the factors affecting trade services quality and have a positive administrative action is developed and tested; the results of evaluation of the customers’ service quality in the consumer cooperative retailers, dynamics of overall and comprehensive indicators of measurement of trade service quality for selected components are given; the main directions and measures for improving trade services quality basing on quantitative values of individual indicators for each of the five selected components (product offering and goods quality, service forms and sale methods, merchandising, services, staff are stated.

  16. Identifying useful project management practices: A mixed methodology approach

    Directory of Open Access Journals (Sweden)

    Gabriela Fernandes

    2013-01-01

    Full Text Available This paper describes a mixed methodological research approach for identifying practitioner perceptions of the most useful project management (PM practices to improve project management performance. By identifying the perceived most useful tools and techniques, as having the most potential for increased contribution to project management performance, practitioners and organizations can select their priorities when improving PM practices. The research involved a programme of thirty interviews with Project Management professionals in Portugal, followed by a global survey. Completed questionnaires were received from 793 practitioners worldwide, covering 75 different countries. The results showed that the top twenty of the list of the most useful tools and techniques is composed of very well-known and widely used tools, such as: progress report; requirements analysis; progress meetings; risk identification; and project scope statement. PM practices in the top of list cover the overall PM life cycle from initiation to project closing, but particular relevance is given to tools and techniques from planning. The areas of knowledge, scope, time, risk, communication and integration, assume a high relevance, each with at least three PM practices on the top of the list.

  17. THE CONTEMPORARY METHODOLOGICAL APPROACHES AND THEORIES EXPLAINING INTERNATIONAL TOURISM FLOWS

    Directory of Open Access Journals (Sweden)

    Zorina SISCAN

    2017-08-01

    Full Text Available Proceeding from the fact that international tourism is in permanent growth the last decades, and contributes signi­ficantly to the development of contemporary national economies, the authors of the article have focused on methodo­logical and theoretical frame that allows deeper understanding of the touristic flows from various aspects. In doing so, the first author has launched some methodological approaches that allow deepening a perspective research on touristic flows while the second author has concentrated upon grouping and analysis of existing theories used to explain touristic flows. As an outcome, the authors recommend a blend of those approaches and theories to be used for an adequate understanding and managing the existing and perspective touristic flows.ABORDDĂRI METODOLOGICE ȘI TEORII CONTEMPORANE CARE EXPLICĂ FLUXURILE DE TURISM INTERNAȚIONALPornind de la faptul că turismul internațional manifestă permanentă creștere în ultimele decenii, precum și contribuie semnificativ la dezvoltarea economiilor naționale contemporane, autorii articolului s-au axat pe cadrul metodologic și teoretic ce ar permite conceperea aprofundată a fluxurilor de turism internațional. Primul autor a lansat unele abordări metodologice care ar contribui la aprofundarea cercetărilor de perspectivă ale fluxurilor turistice, iar cel de-al doilea autor și-a concentrat atenția asupra grupării și analizei teoriilor existente în care se explică natura fluxurilor de turism. Ca rezultat, autorii recomandă utilizarea îmbinării organice a abordărilor și teoriilor considerate pentru perceperea și gestionarea adecvată a fluxurilor de turism existente și de perspectivă.

  18. Q methodology and a Delphi poll: a useful approach to researching a narrative approach to therapy

    OpenAIRE

    2009-01-01

    Q methodology and a Delphi poll combined qualitative and quantitative methods to explore definitions of White and Epston's (1990) narrative approach to therapy among a group of UK practitioners. A Delphi poll was used to generate statements about narrative therapy. The piloting of statements by the Delphi panel identified agreement about theoretical ideas underpinning narrative therapy and certain key practices. A wider group of practitioners ranked the statements in a Q sort and made qualita...

  19. Assessing quality in software development: An agile methodology approach

    National Research Council Canada - National Science Library

    V Rodríguez-Hernández; M C Espino-Gudiño; J L González-Pérez; J Gudiño-Bazaldúa; V M Castaño

    2015-01-01

      A novel methodology, result of 10 years of in-field testing, which makes possible the convergence of different types of models and quality standards for Engineering and Computer Science Faculties, is presented...

  20. Lean methodology: an evidence-based practice approach for healthcare improvement.

    Science.gov (United States)

    Johnson, Pauline M; Patterson, Claire J; OʼConnell, Mary P

    2013-12-10

    Lean methodology, an evidence-based practice approach adopted from Toyota, is grounded on the pillars of respect for people and continuous improvement. This article describes the use of Lean methodology to improve healthcare outcomes for patients with community-acquired pneumonia. Nurse practitioners and other clinicians should be knowledgeable about this methodology and become leaders in Lean transformation.

  1. Methodological Approaches in Conducting Overviews: Current State in HTA Agencies

    Science.gov (United States)

    Pieper, Dawid; Antoine, Sunya-Lee; Morfeld, Jana-Carina; Mathes, Tim; Eikermann, Michaela

    2014-01-01

    Objectives: Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in…

  2. Methodological Metissage: An Interpretive Indigenous Approach to Environmental Education Research

    Science.gov (United States)

    Lowan-Trudeau, Greg

    2012-01-01

    This article discusses the development of a methodological metissage that combined Indigenous and interpretive traditions. This metissage was developed during a doctoral study conducted with Canadian environmental educators who incorporate Western and Indigenous knowledge and philosophy into their ecological identities and pedagogical praxis. It…

  3. Parents' Union Dissolution and Adolescents' School Performance: Comparing Methodological Approaches

    OpenAIRE

    Frisco, Michelle L.; Muller, Chandra; Frank, Kenneth

    2007-01-01

    We use data from the National Longitudinal Study of Adolescent Health and the Adolescent Health and Academic Achievement Study to estimate how parents' union dissolution influences changes in adolescents' mathematics course work gains, overall grade point average, and course failure rates during a window of approximately 1 year (N = 2,629). A primary purpose of this study is demonstrating the utility of propensity score matching techniques for studying topics such as ours that pose methodolog...

  4. Bioscience methodologies in physical chemistry an engineering and molecular approach

    CERN Document Server

    D'Amore, Alberto

    2013-01-01

    The field of bioscience methodologies in physical chemistry stands at the intersection of the power and generality of classical and quantum physics with the minute molecular complexity of chemistry and biology. This book provides an application of physical principles in explaining and rationalizing chemical and biological phenomena. It does not stick to the classical topics that are conventionally considered as part of physical chemistry; instead it presents principles deciphered from a modern point of view, which is the strength of this book.

  5. Assessing quality in software development: An agile methodology approach

    OpenAIRE

    V. Rodríguez-Hernández; M.C. Espino-Gudiño; J.L. González-Pérez; J. Gudiño-Bazaldúa; Victor Castano

    2015-01-01

    A novel methodology, result of 10 years of in-field testing, which makes possible the convergence of different types of models and quality standards for Engineering and Computer Science Faculties, is presented. Since most software-developing companies are small and medium sized, the projects developed must focuson SCRUM and Extreme Programming (XP), opposed to a RUP, which is quite heavy, as well as on Personal Software Process (PSP) and Team Software Process (TSP), which provide students wit...

  6. The Development of Methodology to Support Comprehensive Approach: TMC

    Science.gov (United States)

    2014-05-02

    methodology components, each of which supports a different spectrum of multidisciplinary teamwork . The TMC development has been an iterative process and it...program that aims at exploring new ideas with high potential but high risks. The concept IMAGE developed in this project aimed at improving the...increasing understanding of a complex situation and enabling individuals to share their comprehension. IMAGE is a software toolset concept proposed

  7. The Paradigm of Critical Realism: Approach to an Interdisciplinary Methodology

    Directory of Open Access Journals (Sweden)

    M. A. Tavana

    2015-02-01

    Full Text Available The debate of method of recognition in humanities, social and nature science is one of the apprehensions of Scientists in Wisdom Domain –especially in the modern world. This apprehension, before all things was of appearing in the paradigm of methodoligical between the advocates of the paradigms of positivism with having a share of the natural science. They used to values of naturalism in social and human studies. Additionally, testing and observation and repetition are present as the main terms of recognition. In front, the difference between human studies and natural science is important for the advocates of hermeneutic paradigm. Also, they speak about the methodology of interpretation (understanding of human and social phenomenon. But, in the second half of 20th century another paradigms was established as the Critical realism. This paradigm is tried to parther from the methodoloigcal binary and has a share from the recognition of ontological positivism and epistemological hermeneutics attain to a procedure of interdisciplinary about recognition. So, on the basis of this subject, this article mentioned this question that: would the critical realism receive as the methodology in interdisciplinary? Method of the Article is postulate. This article reasoned that multilayer ontology and epistemology redounded to multilayer methodology that could build up the knowledge of interdisciplinary.

  8. Feminist approaches to social science: epistemological and methodological tenets.

    Science.gov (United States)

    Campbell, R; Wasco, S M

    2000-12-01

    This paper is a primer for community psychologists on feminist research. Much like the field of community psychology, feminist scholarship is defined by its values and process. Informed by the political ideologies of the 1970s women's movement (liberal, radical, socialist feminism, and womanism), feminist scholars reinterpreted classic concepts in philosophy of science to create feminist epistemologies and methodologies. Feminist epistemologies, such as feminist empiricism, standpoint theory, and postmodernism, recognize women's lived experiences as legitimate sources of knowledge. Feminist methodologies attempt to eradicate sexist bias in research and find ways to capture women's voices that are consistent with feminist ideals. Practically, the process of feminist research is characterized by four primary features: (1) expanding methodologies to include both quantitative and qualitative methods, (2) connecting women for group-level data collection, (3) reducing the hierarchical relationship between researchers and their participants to facilitate trust and disclosure, and (4) recognizing and reflecting upon the emotionality of women's lives. Recommendations for how community psychologists can integrate feminist scholarship into their practice are discussed.

  9. A case on vendor selection methodology: An integrated approach

    Directory of Open Access Journals (Sweden)

    Nikhil C. Shil

    2009-11-01

    Full Text Available Vendor selection methodology is a highly researched area in supply chain management l terature and a very significant decision taken by supply chain managers due to technological advances in the manufacturing process. Such research has two basic dimensions: one is related to the identification of variables affecting the performance of the vendors and the other deals with the methodology to be applied. Most of the research conducted in this area deal with the upfront selection of vendors. However, it is very common to have a list of dedicated vendors due to the development of sophisticated production technologies like just in time (JIT, a lean or agile manufacturing process where continuous flow of materials is a requirement. This paper addresses the issue of selecting the optimal vendor from the internal database of a company. Factor analysis, analytical hierarchy process and regression analysis is used in an integrated way to supplement the vendor selection process. The methodology presented here is simply a proposal where every possible room for adjustment is available.

  10. METHODOLOGICAL APPROACHES TO ASSESSING THE EFFICIENCY OF THE INTEGRATION UNITS

    Directory of Open Access Journals (Sweden)

    I. P. Bogomolova

    2014-01-01

    Full Text Available The article examines the scientific and methodological apparatus assessment, built on the basis of the categories of «effectiveness» and «optimality», will allow, on the one hand, to establish the efficiency of functioning of associations in prior periods, on the other - to identify the parameters conditioning condition and results of integrated production in the future. Taking into account the results of these studies, we developed a methodology of integrated assessment of efficiency of functioning of the agro-industrial units. Its essence consists in the determination of the integral coefficient of efficiency on the basis of two complementary groups of settings: performance, expressed in the system of relative indicators, and optimality, the quantitative characteristics of which used the limit values. As the distinctive features of the proposed methodology, determining its scientific novelty and practical significance, it should be noted: enabling the assessment of the effectiveness in using existing and advanced involved in production resources; the use of a unified system of criteria and performance measures and to determine the level of optimality of meat production, built in accordance with the sequence of stages of the reproduction process; universality settlement mechanism, used for the analysis of efficiency of managing the links of the production chain (agriculture, processing, trade and overall integration. The technique involves the execution of the aggregate calculation and analytical operations, grouped by us in the framework of interrelated stages. The result can be identified priority directions of development of the Association, the necessity to optimize the composition of participants and proportions of the process chain, development and implementation of innovative programs, development of new technologies and management methods.

  11. Methodological approach to the evaluation of xenobiotic enffluece on protein molecules

    Directory of Open Access Journals (Sweden)

    M. V. Gorelaya

    2012-03-01

    Full Text Available It was tested and integrated the methodological approach to the research of xenobiotic compounds impact on protein molecules. For this purpose three groups of research methods were used: turbidimetry, immunochemistry and study of the impact on isoelectric point of proteins. The immunochemical methods are most specific. The turbidimetric methods are fastest and informative. Actually, the proposed methodological approach is integrated and versatile. These methods are effective for studying the xenobiotic influence on proteins in living organisms on the assumption of its complex applications. It was proved that this methodological approach is adequate, informative and easy to use.

  12. METHODOLOGICAL APPROACH AND MODEL ANALYSIS FOR IDENTIFICATION OF TOURIST TRENDS

    OpenAIRE

    Neven Šerić; Marijana Jurišić

    2015-01-01

    The draw and diversity of the destination’s offer is an antecedent of the tourism visits growth. The destination supply differentiation is carried through new, specialised tourism products. The usual approach consists of forming specialised tourism products in accordance with the existing tourism destination image. Another approach, prevalent in practice of developed tourism destinations is based on innovating the destination supply through accordance with the global tourism trends. For this ...

  13. The teaching of Zulu first language : methodology and approaches

    OpenAIRE

    2012-01-01

    D.Litt. et Phil The primary aim of this study is to: assess the relevance of the Zulu first language syllabus in respect of its meeting the needs of pupils; investigate and discuss language teaching approaches that may be appropriate to Zulu first language teaching; establish if various types of language syllabuses can be integrated for the enhancement of effective language teaching; integrate teaching approaches. Method of investigation The main method of investigation used was the litera...

  14. A PRACTICAL APPROACH TO THE METHODOLOGY OF ESP TEACHING

    Directory of Open Access Journals (Sweden)

    Carmen D. CARAIMAN

    2014-05-01

    Full Text Available The ability to master specialized terminology in English plays an ever increasing role in the selection of candidates for employment due to the internalization of the labour market and of the research activity exchanges. Subsequent to Romania’s joining the EU, the vacancies available on the European labour market, including in the academic area, represent the major factor that has determined an increase in the interest paid in the acquisition of specialized terminology. This interest is shared by trainees, trainers, authors of textbooks and ESP (English for Specific Purposes specialists. In the present paper, we intend to outline some of the main directions, methods and strategies that an ESP course should follow for providing high-quality and up-to-date information to the trainees interested in acquiring specialized vocabulary for their future workplaces. Finally, we intend to anticipate trends that the evolution of specialized foreign language teaching methodology will follow in the near future.

  15. Response Surface Methodology Approach for the Synthesis of Ethyl Butyrate

    Directory of Open Access Journals (Sweden)

    Vitor Cardoso Aragão

    2011-01-01

    Full Text Available Response surface methodology was used to determine optimum conditions for the esterification of ethanol and butyric acid to produce a flavour ester using immobilized lipase. Various reaction parameters including butyric acid concentration, enzyme concentration, temperature and ethanol/butyric acid molar ratio affecting ethyl butyrate production were investigated using a fractional factorial design 24–1. Based on the results from the first factorial design, all of the variables which were significant in the process were selected to be used in a 24 central composite rotatable design (CCRD. The optimum conditions for the enzymatic reaction were obtained at a 90 mM butyric acid concentration using a 7.7 g/L enzyme concentration at 45 °C and the ethanol/butyric acid molar ratio of 1:1 for 3 h. The esterification percentage, under these conditions, was 87 %.

  16. Parents' Union Dissolution and Adolescents' School Performance: Comparing Methodological Approaches.

    Science.gov (United States)

    Frisco, Michelle L; Muller, Chandra; Frank, Kenneth

    2007-08-01

    We use data from the National Longitudinal Study of Adolescent Health and the Adolescent Health and Academic Achievement Study to estimate how parents' union dissolution influences changes in adolescents' mathematics course work gains, overall grade point average, and course failure rates during a window of approximately 1 year (N = 2,629). A primary purpose of this study is demonstrating the utility of propensity score matching techniques for studying topics such as ours that pose methodological challenges such as dealing with endogeneity and selection bias. We compare propensity score matching techniques to ordinary least squares (OLS) regression methods to show and discuss comparability of results obtained using these different procedures. Findings suggest that associations between parents' union dissolution and achievement may be causal, regardless of method used.

  17. A Methodological Approach to Support Collaborative Media Creation in an E-Learning Higher Education Context

    Science.gov (United States)

    Ornellas, Adriana; Muñoz Carril, Pablo César

    2014-01-01

    This article outlines a methodological approach to the creation, production and dissemination of online collaborative audio-visual projects, using new social learning technologies and open-source video tools, which can be applied to any e-learning environment in higher education. The methodology was developed and used to design a course in the…

  18. SETI and the Historian - Methodological Problems in an Interdisxiplinary Approach

    Science.gov (United States)

    Sivier, D.

    Most discussions of SETI use analogies from human societies and history to illuminate the problems of the emergence of intelligence in the cosmos and assess possible first contact scenarios. These approaches may be flawed due to the radically different approaches traditional scientists and historians have adopted to their subjects and the possibility that human society and consciousness is the product of humanity's unique biological constitution. Traditional historical reasoning provides the necessary caveat that historical outcomes are not inevitable, and that technological development is by no means certain, even when scientific preconditions for it have been fulfilled. Nevertheless, the consilience offered by sociobiology on the one hand and a more speculative approach by historians to their subject on the other means that a fertile cross-pollination between the humanities and sciences is underway which may give greater insights into both the human condition and the nature and likelihood of ETI.

  19. The Assessment Methodology RADAR – A Theoretical Approach of a Methodology for Coordinating the Efforts to Improve the Organizational Processes to Achieve Excellence

    Directory of Open Access Journals (Sweden)

    Cristina Raluca Popescu

    2015-05-01

    Full Text Available In the paper “The Assessment Methodology RADAR – A Theoretical Approach of a Methodology for Coordinating the Efforts to Improve the Organizational Processes to Achieve Excellence” the authors present the basic features of the assessment methodology RADAR that is designed to coordinate the efforts to improve the organizational processes in order to achieve excellence.

  20. 50 Years of coastal erosion analysis: A new methodological approach.

    Science.gov (United States)

    Prieto Campos, Antonio; Diaz Cuevas, Pilar; Ojeda zujar, Jose; Guisado-Pintado, Emilia

    2017-04-01

    Coasts over the world have been subjected to increased anthropogenic pressures which combined with natural hazards impacts (storm events, rising sea-levels) have led to strong erosion problems with negative impacts on the economy and the safety of coastal communities. The Andalusian coast (South Spain) is a renowned global tourist destination. In the past decades a deep transformation in the economic model led to significant land use changes: strong regulation of rivers, urbanisation and occupation of dunes, among others. As a result irreversible transformations on the coastline, from the aggressive urbanisation undertaken, are now to be faced by local authorities and suffered by locals and visitors. Moreover, the expected impacts derived from the climate change aggravated by anthropic activities emphasises the need for tools that facilitates decision making for a sustainable coastal management. In this contribution a homogeneous (only a proxy and one photointerpreter) methodology is proposed for the calculation of coastal erosion rates of exposed beaches in Andalusia (640 km) through the use of detailed series (1:2500) of open source orthophotographies for the period (1956-1977-2001-2011). The outstanding combination of the traditional software DSAS (Digital Shoreline Analysis System) with a spatial database (PostgreSQL) which integrates the resulting erosion rates with related coastal thematic information (geomorphology, presence of engineering infrastructures, dunes and ecosystems) enhances the capacity of analysis and exploitation. Further, the homogeneity of the method used allows the comparison of the results among years in a highly diverse coast, with both Mediterranean and Atlantic façades. The novelty development and integration of a PostgreSQL/Postgis database facilitates the exploitation of the results by the user (for instance by relating calculated rates with other thematic information as geomorphology of the coast or the presence of a dune field on

  1. The Keystone Approach: Integration of Methodology and Technology

    Science.gov (United States)

    Siadat, M. Vali; Peterson, Euguenia; Oseledets, Cyrill; Wang, Ming-Jer; Zhang, Guo Quan

    2012-01-01

    This article is the result of a comprehensive research study investigating the impact of computer-learning technology as well as the impact of a synergistic teaching approach (Keystone Method) on developmental mathematics classes at the college level. The study focused on mathematics skills of elementary and intermediate algebra students and…

  2. Assessment of soil nutrient balance: approaches and methodologies

    NARCIS (Netherlands)

    Roy, R.N.; Misra, R.V.; Lesschen, J.P.; Smaling, E.M.A.

    2003-01-01

    Nutrient-balance assessments are valuable tools for delineating the consequences of farming on soil fertility. Various approaches and methods for different situations have been used. This bulletin presents a state-of-the-art overview of nutrient-balance studies. It brings out the evolution of the ap

  3. Monitoring contaminant strategies: tools, techniques, methodologies and model approaches

    Science.gov (United States)

    A century-long history of experiments on solute transport in soils has resulted in a wide range of experimental setups and procedures, as well as methods for interpreting observations which has led to considerable ambiguity regarding monitoring approaches. This presentation will focus on results an...

  4. Methodological Approaches To Economic Evaluation Of Forest Resources

    OpenAIRE

    Igor Lytsur

    2012-01-01

    The article formed the complex process of economic assessment of forest resources and given it's definition. A new approach to determining costs for locking the main types of forest. Allocated forestry (in Keywords: forest) and forest harvesting (in forest exploitation) rents.

  5. Materialized View Selection Approach Using Tree Based Methodology

    Directory of Open Access Journals (Sweden)

    MR. P. P. KARDE

    2010-10-01

    Full Text Available In large databases particularly in distributed database, query response time plays an important role as timely access to information and it is the basic requirement of successful business application. A data warehouse uses multiple materialized views to efficiently process a given set of queries. Quick response time and accuracy areimportant factors in the success of any database. The materialization of all views is not possible because of the space constraint and maintenance cost constraint. Selection of Materialized views is one of the most important decisions in designing a data warehouse for optimal efficiency. Selecting a suitable set of views that minimizesthe total cost associated with the materialized views and is the key component in data warehousing. Materialized views are found to be very useful for fast query processing. This paper gives the results of proposed tree based materialized view selection algorithm for query processing. In distributed environment where database is distributed over the nodes on which query should get executed and also plays an important role. This paper also proposes node selection algorithm for fast materialized view selection in distributed environment. And finally it is found that the proposed methodology performs better for query processing as compared to other materializedview selection strategies.

  6. A Methodology for assessing Agile Software Development Approaches

    CERN Document Server

    Soundararajan, Shvetha

    2011-01-01

    Agile methods provide an organization or a team the flexibility to adopt a selected subset of principles and practices based on their culture, their values, and the types of systems that they develop. More specifically, every organization or team implements a customized agile method, tailored to better accommodate its needs. However, the extent to which a customized method supports the organizational objectives, or rather the 'goodness' of that method is questionable. Existing agile assessment approaches focus on a comparative analysis, or are limited in scope and application. In this research, we propose a structured, systematic and comprehensive approach to assess the 'goodness' of agile methods. We examine an agile method based on (1) its adequacy, (2) the capability of the organization to support the adopted principles and practices specified by the method, and (3) the method's effectiveness. We propose the Objectives, Principles and Practices (OPP) Framework to guide our assessment. The Framework identif...

  7. New approaches in intelligent control techniques, methodologies and applications

    CERN Document Server

    Kountchev, Roumen

    2016-01-01

    This volume introduces new approaches in intelligent control area from both the viewpoints of theory and application. It consists of eleven contributions by prominent authors from all over the world and an introductory chapter. This volume is strongly connected to another volume entitled "New Approaches in Intelligent Image Analysis" (Eds. Roumen Kountchev and Kazumi Nakamatsu). The chapters of this volume are self-contained and include summary, conclusion and future works. Some of the chapters introduce specific case studies of various intelligent control systems and others focus on intelligent theory based control techniques with applications. A remarkable specificity of this volume is that three chapters are dealing with intelligent control based on paraconsistent logics.

  8. The Case Study Approach: Some Theoretical, Methodological and Applied Considerations

    Science.gov (United States)

    2013-06-01

    a large manufacturing organisation in Malaysia . An in- depth case study process (specifically a qualitative approach) was used to illustrate the...researcher closely examined four leaders from generally diverse organisations, who had embraced the learning-organisation concept in order to improve...The researchers focused on the context of learning in the workplace , and they investigated the nature of learning and development opportunities that

  9. Oxfordian and Kimmeridgian "Aspidoceras" in the Mediterranean. A methodological approach

    Directory of Open Access Journals (Sweden)

    Olóriz, F.

    1987-12-01

    Full Text Available In this study we present a contrastive analysis of the Null Hypothesis, established as the methodological basis for the evolutive investigation of Mediterranean "Aspidoceras" (Checa & Olóriz, 1985. This contrast is carried out using new data, and is part of a research programme which has been carefully planned. Paleogeographic, sedimentological. stratigraphic and palcobiological considerations have provided new evolutive models which in turn lead to a structural reorganization of thc Null Hypothesis. In this new structure, the Basic Evolutionary Conformations are no longer considcred as mere morphological groupings, the result of a direct reading of thc fossil record. In this way we propose morphological blocks, representing evolutive units which can be related to one another.En el presente trabajo se lleva a cabo un análisis contrastador de la Hipótesis Nula establecida como base metodológica para la investigación evolutiva de los"Aspidoceras" mediterráneos (Checa & Olóriz, 1985. Esta contrastación se lleva a cabo integrando nuevos datos y forma parte de un programa de investigación cuidadosamente planificado. Las diversas consideraciones paleogeográficas, sedimentológicas, estratigráficas y paleobiológicas han proporcionado nuevos modelos evolutivos que suponen una sustancial reorganización estructural de la Hipótesis Nula. En esta estructuración, las Configuraciones Evolutivas Básicas no son consideradas como meros grupos morfológicos, resultado de una lectura del registro fósil, sino que constituyen unidades evolutivas que pueden, por tanto, relacionarse entre sí.

  10. Supply chain value creation methodology under BSC approach

    Science.gov (United States)

    Golrizgashti, Seyedehfatemeh

    2014-06-01

    The objective of this paper is proposing a developed balanced scorecard approach to measure supply chain performance with the aim of creating more value in manufacturing and business operations. The most important metrics have been selected based on experts' opinion acquired by in-depth interviews focused on creating more value for stakeholders. Using factor analysis method, a survey research has been used to categorize selected metrics into balanced scorecard perspectives. The result identifies the intensity of correlation between perspectives and cause-and-effect chains among them using statistical method based on a real case study in home appliance manufacturing industries.

  11. A Methodological Approach to the Materiality of Clothing

    DEFF Research Database (Denmark)

    Klepp, Ingun Grimstad; Bjerck, Mari

    2014-01-01

    clothes relate to each other on the whole or within parts of the wardrobe. More specifically, we discuss how this method can contribute to increasing the materiality of clothes studies. The theoretical point of departure for this approach is a practice theory in which the material enters as an integral...... part. First, the article briefly discusses developments within the study of dress and fashion. Second, the methods combined and developed in wardrobe studies are discussed. The emphasis here is primarily not only on the weaknesses of the individual methods in practice-oriented dress studies, but also...

  12. METHODOLOGICAL APPROACH AND MODEL ANALYSIS FOR IDENTIFICATION OF TOURIST TRENDS

    Directory of Open Access Journals (Sweden)

    Neven Šerić

    2015-06-01

    Full Text Available The draw and diversity of the destination’s offer is an antecedent of the tourism visits growth. The destination supply differentiation is carried through new, specialised tourism products. The usual approach consists of forming specialised tourism products in accordance with the existing tourism destination image. Another approach, prevalent in practice of developed tourism destinations is based on innovating the destination supply through accordance with the global tourism trends. For this particular purpose, it is advisable to choose a monitoring and analysis method of tourism trends. The goal is to determine actual trends governing target markets, differentiating whims from trends during the tourism preseason. When considering the return on investment, modifying the destination’s tourism offer on the basis of a tourism whim is a risky endeavour, indeed. Adapting the destination’s supply to tourism whims can result in a shifted image, one that is unable to ensure a long term interest and tourist vacation growth. With regard to tourism trend research and based on the research conducted, an advisable model for evaluating tourism phenomena is proposed, one that determines whether tourism phenomena is a tourism trend or a tourism whim.

  13. New approaches in intelligent image analysis techniques, methodologies and applications

    CERN Document Server

    Nakamatsu, Kazumi

    2016-01-01

    This book presents an Introduction and 11 independent chapters, which are devoted to various new approaches of intelligent image processing and analysis. The book also presents new methods, algorithms and applied systems for intelligent image processing, on the following basic topics: Methods for Hierarchical Image Decomposition; Intelligent Digital Signal Processing and Feature Extraction; Data Clustering and Visualization via Echo State Networks; Clustering of Natural Images in Automatic Image Annotation Systems; Control System for Remote Sensing Image Processing; Tissue Segmentation of MR Brain Images Sequence; Kidney Cysts Segmentation in CT Images; Audio Visual Attention Models in Mobile Robots Navigation; Local Adaptive Image Processing; Learning Techniques for Intelligent Access Control; Resolution Improvement in Acoustic Maps. Each chapter is self-contained with its own references. Some of the chapters are devoted to the theoretical aspects while the others are presenting the practical aspects and the...

  14. A multi-sensory methodological approach for science learning

    Directory of Open Access Journals (Sweden)

    Eugenia Lucia Bossio

    2016-04-01

    Full Text Available This paper presents both a learning environment aimed at science education and the results obtained at the end of its experimentation carried out in a secondary school. The edutainment environment has been designed to explain the physical theory of superstrings, and it was mainly based on the construction of artifacts and on the manipulation of digital media. In order to both intrigue students and make interesting and appealing this complex subject of physics we have tried to stimulate and engage students in a multi-sensory way through different approaches. It was outlined a path made by different steps to deal with the scientific issues addressed that would actively encourage a real translation of knowledge into skills and both different styles and ways of learning. Superstring theory was first presented through traditional approaches and, later, through the construction of metaphoric representations made by artifacts created by the students. The experimentation, conducted on a group of 20 students, allowed to evaluate the effectiveness of the environment. Un approccio multisensoriale per l’apprendimento delle scienzeQuesto articolo presenta un ambiente di apprendimento rivolto alla didattica delle scienze e i risultati ottenuti al termine della sua sperimentazione compiuta presso un istituto scolastico d’istruzione secondaria di primo grado. L’ambiente di edutainment è stato progettato per realizzare la divulgazione della teoria fisica delle superstringhe, ed è stato prevalentemente basato sulla costruzione di manufatti e sulla manipolazione di media digitali. Si è cercato di stimolare e coinvolgere gli alunni mediante approcci diversi e in maniera multisensoriale con l’obiettivo di incuriosirli rendendo interessante e accattivante questo complesso argomento della fisica. È stato delineato un percorso per gradi alle problematiche scientifiche affrontate che potesse attivamente stimolare sia i vari stili e modi di apprendimento

  15. Brown Adipose Tissue Bioenergetics: A New Methodological Approach

    Science.gov (United States)

    Calderon‐Dominguez, María; Alcalá, Martín; Sebastián, David; Zorzano, Antonio; Viana, Marta; Serra, Dolors

    2017-01-01

    The rediscovery of brown adipose tissue (BAT) in humans and its capacity to oxidize fat and dissipate energy as heat has put the spotlight on its potential as a therapeutic target in the treatment of several metabolic conditions including obesity and diabetes. To date the measurement of bioenergetics parameters has required the use of cultured cells or extracted mitochondria with the corresponding loss of information in the tissue context. Herein, we present a method to quantify mitochondrial bioenergetics directly in BAT. Based on XF Seahorse Technology, we assessed the appropriate weight of the explants, the exact concentration of each inhibitor in the reaction, and the specific incubation time to optimize bioenergetics measurements. Our results show that BAT basal oxygen consumption is mostly due to proton leak. In addition, BAT presents higher basal oxygen consumption than white adipose tissue and a positive response to b‐adrenergic stimulation. Considering the whole tissue and not just subcellular populations is a direct approach that provides a realistic view of physiological respiration. In addition, it can be adapted to analyze the effect of potential activators of thermogenesis, or to assess the use of fatty acids or glucose as a source of energy. PMID:28435771

  16. Putting Foucault to work: an approach to the practical application of Foucault's methodological imperatives

    Directory of Open Access Journals (Sweden)

    DAVID A. NICHOLLS

    2009-01-01

    Full Text Available This paper presents an overview of the methodological approach taken in a recently completed Foucauldian discourse analysis of physiotherapy practice. In keeping with other approaches common to postmodern research this paper resists the temptation to define a proper or ‘correct’ interpretation of Foucault’s methodological oeuvre; preferring instead to apply a range of Foucauldian propositions to examples drawn directly from the thesis. In the paper I elucidate on the blended archaeological and genealogical approach I took and unpack some of the key imperatives, principles and rules I grappled with in completing the thesis.

  17. Using Q Methodology in the Literature Review Process: A Mixed Research Approach

    Science.gov (United States)

    Onwuegbuzie, Anthony J.; Frels, Rebecca K.

    2015-01-01

    Because of the mixed research-based nature of literature reviews, it is surprising, then, that insufficient information has been provided as to how reviewers can incorporate mixed research approaches into their literature reviews. Thus, in this article, we provide a mixed methods research approach--Q methodology--for analyzing information…

  18. Methods in the Madness: Integrative Approaches to Methodology in Introductory Comparative Politics

    Science.gov (United States)

    Dickovick, J. Tyler

    2009-01-01

    This paper outlines an integrative approach to teaching (qualitative) comparative methods at the introductory undergraduate level. The integrative approach does not view methodological instruction as a topic to be treated cursorily at the outset of a course, but rather one to be intertwined throughout an academic term as students simultaneously…

  19. Methods in the Madness: Integrative Approaches to Methodology in Introductory Comparative Politics

    Science.gov (United States)

    Dickovick, J. Tyler

    2009-01-01

    This paper outlines an integrative approach to teaching (qualitative) comparative methods at the introductory undergraduate level. The integrative approach does not view methodological instruction as a topic to be treated cursorily at the outset of a course, but rather one to be intertwined throughout an academic term as students simultaneously…

  20. Landslide risk analysis: a multi-disciplinary methodological approach

    Directory of Open Access Journals (Sweden)

    S. Sterlacchini

    2007-11-01

    damage ranged considerably from 2 840 000 to 9 350 000 €, depending on the selected temporal scenario and the expected closing time of the potentially affected structures.

    The multi-disciplinary approach discussed in this study may assist local decision makers in determining the nature and magnitude of the expected losses due to a dangerous event, which can be anticipated in a given study area, during a specified time period. Besides, a preventive knowledge of the prospective physical effects and economic consequences may help local decision makers to choose the best prevention and mitigation options and to decide how to allocate resources properly, so that potential benefits are maximised at an acceptable cost.

  1. Approaches to qualitative research in mathematics education examples of methodology and methods

    CERN Document Server

    Bikner-Ahsbahs, Angelika; Presmeg, Norma

    2014-01-01

    This volume documents a range of qualitative research approaches emerged within mathematics education over the last three decades, whilst at the same time revealing their underlying methodologies. Continuing the discussion as begun in the two 2003 ZDM issues dedicated to qualitative empirical methods, this book presents astate of the art overview on qualitative research in mathematics education and beyond. The structure of the book allows the reader to use it as an actual guide for the selection of an appropriate methodology, on a basis of both theoretical depth and practical implications. The methods and examples illustrate how different methodologies come to life when applied to a specific question in a specific context. Many of the methodologies described are also applicable outside mathematics education, but the examples provided are chosen so as to situate the approach in a mathematical context.

  2. Trends and Findings in Trajectory Studies: a Methodological Approach to Classify Labor Development

    Directory of Open Access Journals (Sweden)

    Mariela Sonia Jiménez Vásquez

    2009-05-01

    Full Text Available Trajectory studies are a methodological option that helps to completely analyze labor paths forged by individuals in the labor market. However, when initiating a research in this topic there are several different scopes, discipline approaches, objects and purposes of research, which hinder its comprehension. This article presents the main trends established to guide this type of research and some of the theoretical and methodological elements found in its structure.

  3. Methodologic model to scheduling on service systems: a software engineering approach

    Directory of Open Access Journals (Sweden)

    Eduyn Ramiro Lopez-Santana

    2016-06-01

    Full Text Available This paper presents an approach of software engineering to a research proposal to make an Expert System to scheduling on service systems using methodologies and processes of software development. We use the adaptive software development as methodology for the software architecture based on the description as a software metaprocess that characterizes the research process. We make UML’s diagrams (Unified Modeling Language to provide a visual modeling that describes the research methodology in order to identify the actors, elements and interactions in the research process.

  4. Quantifying biopsychosocial aspects in everyday contexts: an integrative methodological approach from the behavioral sciences

    Directory of Open Access Journals (Sweden)

    Portell M

    2015-06-01

    Full Text Available Mariona Portell,1 M Teresa Anguera,2 Antonio Hernández-Mendo,3 Gudberg K Jonsson4 1Department of Psychobiology and Methodology of Health Sciences, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain; 2Department of Methodology of Behavioral Sciences, University of Barcelona, Barcelona, Spain; 3Department Social Psychology, Social Anthropology, Social Work and Social Services, University of Málaga, Málaga, Spain; 4Human Behavior Laboratory, University of Iceland, Reykjavík, Iceland Abstract: Contextual factors are crucial for evaluative research in psychology, as they provide insights into what works, for whom, in what circumstances, in what respects, and why. Studying behavior in context, however, poses numerous methodological challenges. Although a comprehensive framework for classifying methods seeking to quantify biopsychosocial aspects in everyday contexts was recently proposed, this framework does not contemplate contributions from observational methodology. The aim of this paper is to justify and propose a more general framework that includes observational methodology approaches. Our analysis is rooted in two general concepts: ecological validity and methodological complementarity. We performed a narrative review of the literature on research methods and techniques for studying daily life and describe their shared properties and requirements (collection of data in real time, on repeated occasions, and in natural settings and classification criteria (eg, variables of interest and level of participant involvement in the data collection process. We provide several examples that illustrate why, despite their higher costs, studies of behavior and experience in everyday contexts offer insights that complement findings provided by other methodological approaches. We urge that observational methodology be included in classifications of research methods and techniques for studying everyday behavior and advocate a renewed

  5. Quantifying biopsychosocial aspects in everyday contexts: an integrative methodological approach from the behavioral sciences

    Science.gov (United States)

    Portell, Mariona; Anguera, M Teresa; Hernández-Mendo, Antonio; Jonsson, Gudberg K

    2015-01-01

    Contextual factors are crucial for evaluative research in psychology, as they provide insights into what works, for whom, in what circumstances, in what respects, and why. Studying behavior in context, however, poses numerous methodological challenges. Although a comprehensive framework for classifying methods seeking to quantify biopsychosocial aspects in everyday contexts was recently proposed, this framework does not contemplate contributions from observational methodology. The aim of this paper is to justify and propose a more general framework that includes observational methodology approaches. Our analysis is rooted in two general concepts: ecological validity and methodological complementarity. We performed a narrative review of the literature on research methods and techniques for studying daily life and describe their shared properties and requirements (collection of data in real time, on repeated occasions, and in natural settings) and classification criteria (eg, variables of interest and level of participant involvement in the data collection process). We provide several examples that illustrate why, despite their higher costs, studies of behavior and experience in everyday contexts offer insights that complement findings provided by other methodological approaches. We urge that observational methodology be included in classifications of research methods and techniques for studying everyday behavior and advocate a renewed commitment to prioritizing ecological validity in behavioral research seeking to quantify biopsychosocial aspects. PMID:26089708

  6. Predicting pilot error: testing a new methodology and a multi-methods and analysts approach.

    Science.gov (United States)

    Stanton, Neville A; Salmon, Paul; Harris, Don; Marshall, Andrew; Demagalski, Jason; Young, Mark S; Waldmann, Thomas; Dekker, Sidney

    2009-05-01

    The Human Error Template (HET) is a recently developed methodology for predicting design-induced pilot error. This article describes a validation study undertaken to compare the performance of HET against three contemporary Human Error Identification (HEI) approaches when used to predict pilot errors for an approach and landing task and also to compare analyst error predictions to an approach to enhancing error prediction sensitivity: the multiple analysts and methods approach, whereby multiple analyst predictions using a range of HEI techniques are pooled. The findings indicate that, of the four methodologies used in isolation, analysts using the HET methodology offered the most accurate error predictions, and also that the multiple analysts and methods approach was more successful overall in terms of error prediction sensitivity than the three other methods but not the HET approach. The results suggest that when predicting design-induced error, it is appropriate to use a toolkit of different HEI approaches and multiple analysts in order to heighten error prediction sensitivity.

  7. Researching Memories about Starting School: Autobiographical Narratives as a Methodological Approach

    Science.gov (United States)

    Turunen, Tuija A.; Dockett, Sue; Perry, Bob

    2015-01-01

    This article reports on methodological issues in the study of autobiographical narratives about transition to school within a life course approach. The data consist of 89 Australian participants' recollections of starting school between 1928 and 1995. These narratives are considered as life reviews and part of the story of "continuing…

  8. Speaking Back to the Deficit Discourses: A Theoretical and Methodological Approach

    Science.gov (United States)

    Hogarth, Melitta

    2017-01-01

    The educational attainment of Aboriginal and Torres Strait Islander students is often presented within a deficit view. The need for Aboriginal and Torres Strait Islander researchers to challenge the societal norms is necessary to contribute to the struggle for self-determination. This paper presents a theoretical and methodological approach that…

  9. Theoretic-methodological approaches to determine the content and classification of innovation-investment development strategies

    Directory of Open Access Journals (Sweden)

    Gerashenkova Tatyana

    2016-01-01

    Full Text Available The article states the necessity to form an innovation-investment strategy of enterprise development, offers an approach to its classification, determines the place of this strategy in a corporatewide strategy, gives the methodology of formation and the realization form of the innovation-investment development strategy.

  10. Methodological approaches to developing a plan of land and economic unit of the settlement

    OpenAIRE

    Dorosh, O.

    2015-01-01

    This paper deals with problematic of legislation, the legal relations regulated by which are associated with the use of land in the settlements of Ukraine. Methodological approaches on the development of the plan on land-economic settlements unit have been suggested. It is proved that the land management documentation provides an effective planning of the territorial development of urban and rural settlements.

  11. The development of methodological approach to management of capital adequacy of insurance company through reinsurance

    Directory of Open Access Journals (Sweden)

    Opeshko Nataliya Sergiivna

    2015-02-01

    Full Text Available The article defines the essence of capital adequacy of insurance company. Theoretical aspects of estimation capital adequacy of insurer in accordance with the requirements of the Directive Solvency II are discussed. The methodological approach to management of capital adequacy of insurance company through reinsurance is developed in the article. The usefulness of using the developed approach for managing capital adequacy ratio is proved on the basis of conducted experiments.

  12. Methodological Approaches and Principles of Foreign Language Teachers’ Training to Provide Schoolchildren with Ethnic Education

    Directory of Open Access Journals (Sweden)

    Botakoz A. Zhekibaeva

    2013-01-01

    Full Text Available The article presents description of the main methodological approaches and principles of foreign language teachers’ training to provide schoolchildren with ethic education, including: person-centered, ethno-cultural, didactic, ethno-pedagogical, system, pragmatic approaches and principles of cultural conformity, dialectical unity of universal and national-ethnic, dialogue and cultural interaction. This analysis of methodological approaches and principles allowed us to define the content of foreign language teachers’ training to provide schoolchildren with ethic education, including combination of ethnic education knowledge, skills, its essence and features and to identify the forms, methods and means of teaching, enabling to train the foreign language teachers this branch of activity in the shortest time

  13. Adopting a Grounded Theory Approach to Cultural-Historical Research: Conflicting Methodologies or Complementary Methods?

    Directory of Open Access Journals (Sweden)

    Jayson Seaman PhD

    2008-03-01

    Full Text Available Grounded theory has long been regarded as a valuable way to conduct social and educational research. However, recent constructivist and postmodern insights are challenging long-standing assumptions, most notably by suggesting that grounded theory can be flexibly integrated with existing theories. This move hinges on repositioning grounded theory from a methodology with positivist underpinnings to an approach that can be used within different theoretical frameworks. In this article the author reviews this recent transformation of grounded theory, engages in the project of repositioning it as an approach by using cultural historical activity theory as a test case, and outlines several practical methods implied by the joint use of grounded theory as an approach and activity theory as a methodology. One implication is the adoption of a dialectic, as opposed to a constructivist or objectivist, stance toward grounded theory inquiry, a stance that helps move past the problem of emergence versus forcing.

  14. Q-methodology: an alternative approach to research in nurse education.

    Science.gov (United States)

    Barker, Janet H

    2008-11-01

    An understanding of student experiences and perspectives are central to the delivery of quality nurse education programmes; implicit with this is a need to understand the attributes and characteristics of such individuals, their subjectivity. Traditional such inquiry has taken the form of questionnaires or interviews and focus groups. Q-methodology is offered as an alternative approach which provides insight into, and a method for studying, individual subjectivity through the use of factor analysis. Within Q-methodology, individuals are asked to rank-order (Q-sort) statements, which are then intercorrelated and subjected to factor analysis. In this way groups of individuals holding similar expressed subjectivities are identified. The factors are interpreted to provide an understanding of underlying subjectivities. This paper explores the theoretical underpinnings of Q-methodology and its application as a research method in the field of nurse education, providing a brief illustration of its use in mental health nurse education.

  15. Identifying approaches for assessing methodological and reporting quality of systematic reviews

    DEFF Research Database (Denmark)

    Pussegoda, Kusala; Turner, Lucy; Garritty, Chantelle

    2017-01-01

    there are potential gaps in research best-practice guidance materials. The aims of this study are to identify reports assessing the methodological quality (MQ) and/or reporting quality (RQ) of a cohort of SRs and to assess their number, general characteristics, and approaches to 'quality' assessment over time......BACKGROUND: The methodological quality and completeness of reporting of the systematic reviews (SRs) is fundamental to optimal implementation of evidence-based health care and the reduction of research waste. Methods exist to appraise SRs yet little is known about how they are used in SRs or where....... CONCLUSIONS: The methods used to assess quality of SRs are diverse, and none has become universally accepted. The most commonly used quality assessment tools are AMSTAR, OQAQ, and PRISMA. As new tools and guidelines are developed to improve both the MQ and RQ of SRs, authors of methodological studies...

  16. The intersubjective endeavour of psychopathology research: methodological reflections on a second person perspective approach

    Directory of Open Access Journals (Sweden)

    Laura eGalbusera

    2014-10-01

    Full Text Available Research in psychopathology may be considered as an intersubjective endeavor mainly concerned with understanding other minds. Thus, the way we conceive of social understanding influences how we do research in psychology in the first place. In this paper, we focus on psychopathology research as a paradigmatic case for this methodological issue, since the relation between the researcher and the object of study is characterized by a major component of otherness.We critically review different methodologies in psychopathology research, highlighting their relation to different social cognition theories (the third-, first- and second-person approaches. Hence we outline the methodological implications arising from each theoretical stance. Firstly, we critically discuss the dominant paradigm in psychopathology research, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM, American Psychiatric Association, 2013 and on quantitative methodology, as an example of a third person methodology. Secondly, we contrast this mainstream view with phenomenological psychopathology which - by rejecting the reductionist view exclusively focused on behavioural symptoms - takes consciousness as its main object of study: it therefore attempts to grasp patients’ first person experience. But how can we speak about a first person perspective in psychopathology if the problem at stake is the experience of the other? How is it possible to understand the experience from within, if the person who is having this experience is another? By addressing these issues, we critically explore the feasibility and usefulness of a second person methodology in psychopathology research. Notwithstanding the importance of methodological pluralism, we argue that a second person perspective should inform the epistemology and methods of research in psychopathology, as it

  17. The intersubjective endeavor of psychopathology research: methodological reflections on a second-person perspective approach.

    Science.gov (United States)

    Galbusera, Laura; Fellin, Lisa

    2014-01-01

    Research in psychopathology may be considered as an intersubjective endeavor mainly concerned with understanding other minds. Thus, the way we conceive of social understanding influences how we do research in psychology in the first place. In this paper, we focus on psychopathology research as a paradigmatic case for this methodological issue, since the relation between the researcher and the object of study is characterized by a major component of "otherness." We critically review different methodologies in psychopathology research, highlighting their relation to different social cognition theories (the third-, first-, and second-person approaches). Hence we outline the methodological implications arising from each theoretical stance. Firstly, we critically discuss the dominant paradigm in psychopathology research, based on the Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 2013) and on quantitative methodology, as an example of a third-person methodology. Secondly, we contrast this mainstream view with phenomenological psychopathology which-by rejecting the reductionist view exclusively focused on behavioral symptoms-takes consciousness as its main object of study: it therefore attempts to grasp patients' first-person experience. But how can we speak about a first-person perspective in psychopathology if the problem at stake is the experience of the other? How is it possible to understand the experience from "within," if the person who is having this experience is another? By addressing these issues, we critically explore the feasibility and usefulness of a second-person methodology in psychopathology research. Notwithstanding the importance of methodological pluralism, we argue that a second-person perspective should inform the epistemology and methods of research in psychopathology, as it recognizes the fundamental circular and intersubjective construction of knowledge.

  18. Adapting to Uncertainty: Comparing Methodological Approaches to Climate Adaptation and Mitigation Policy

    Science.gov (United States)

    Huda, J.; Kauneckis, D. L.

    2013-12-01

    Climate change adaptation represents a number of unique policy-making challenges. Foremost among these is dealing with the range of future climate impacts to a wide scope of inter-related natural systems, their interaction with social and economic systems, and uncertainty resulting from the variety of downscaled climate model scenarios and climate science projections. These cascades of uncertainty have led to a number of new approaches as well as a reexamination of traditional methods for evaluating risk and uncertainty in policy-making. Policy makers are required to make decisions and formulate policy irrespective of the level of uncertainty involved and while a debate continues regarding the level of scientific certainty required in order to make a decision, incremental change in the climate policy continues at multiple governance levels. This project conducts a comparative analysis of the range of methodological approaches that are evolving to address uncertainty in climate change policy. It defines 'methodologies' to include a variety of quantitative and qualitative approaches involving both top-down and bottom-up policy processes that attempt to enable policymakers to synthesize climate information into the policy process. The analysis examines methodological approaches to decision-making in climate policy based on criteria such as sources of policy choice information, sectors to which the methodology has been applied, sources from which climate projections were derived, quantitative and qualitative methods used to deal with uncertainty, and the benefits and limitations of each. A typology is developed to better categorize the variety of approaches and methods, examine the scope of policy activities they are best suited for, and highlight areas for future research and development.

  19. Developing a methodology to assess the impact of research grant funding: a mixed methods approach.

    Science.gov (United States)

    Bloch, Carter; Sørensen, Mads P; Graversen, Ebbe K; Schneider, Jesper W; Schmidt, Evanthia Kalpazidou; Aagaard, Kaare; Mejlgaard, Niels

    2014-04-01

    This paper discusses the development of a mixed methods approach to analyse research funding. Research policy has taken on an increasingly prominent role in the broader political scene, where research is seen as a critical factor in maintaining and improving growth, welfare and international competitiveness. This has motivated growing emphasis on the impacts of science funding, and how funding can best be designed to promote socio-economic progress. Meeting these demands for impact assessment involves a number of complex issues that are difficult to fully address in a single study or in the design of a single methodology. However, they point to some general principles that can be explored in methodological design. We draw on a recent evaluation of the impacts of research grant funding, discussing both key issues in developing a methodology for the analysis and subsequent results. The case of research grant funding, involving a complex mix of direct and intermediate effects that contribute to the overall impact of funding on research performance, illustrates the value of a mixed methods approach to provide a more robust and complete analysis of policy impacts. Reflections on the strengths and weaknesses of the methodology are used to examine refinements for future work.

  20. Methodological requirements of the competitive approach in tourist formation of the future teachers

    Directory of Open Access Journals (Sweden)

    Dudorova L.J.

    2014-03-01

    Full Text Available Purpose: to prove methodological requirements of the competetive approach in the tourist preparation of the future teachers. Material : the research work was made on the basis of studying of references, the analysis and synthesis of the received information, with the usage of the method of pedagogical designing. Results: methodological requirements of the competetive approach in tourist formation of the future teachers are considered and concretised. The methods of objective diagnosing of tourist preparation of the future teacher is opened. It is noticed that for objective diagnosing are necessary not only the subject (as it descends in traditional training, but also the system, professionally oriented criteria, allowing to measure level of forming of tourist competence of the future teacher. Conclusions: the universal structure of tourist competence of the future teachers consists of following components: motivational; cognitive; praxeological; individually-psychologic; the subjective. The assessment of these components allows to define complex level of forming of tourist competence of the future teacher.

  1. A methodological approach based on indirect sampling to survey the homeless people

    OpenAIRE

    Claudia De Vitiis; Stefano Falorsi; Francesca Inglese; Alessandra Masi; Nicoletta Pannuzi; Monica Russo

    2014-01-01

    The Italian National Institute of Statistics carried out the first survey on homeless population. The survey aims at estimating the unknown size and some demographic and social characteristics of this population. The methodological strategy used to investigate homeless population could not follow the standard approaches of official statistics usually based on the use of population lists. The sample strategy for the homeless survey refers to the theory of indirect sampling, based on the use of...

  2. Formation of a Methodological Approach to Evaluating the State of Management of Enterprise Flow Processes

    Directory of Open Access Journals (Sweden)

    Dzobko Iryna P.

    2016-02-01

    Full Text Available The formation of a methodological approach to evaluating management of the state of enterprise flow processes has been considered. Proceeding from the developed and presented in literary sources theoretical propositions on organization of management of enterprise flow processes, the hypothesis of the study is correlation of quantitative and qualitative evaluations of management effectiveness and formation of the integral index on their basis. The article presents stages of implementation of a methodological approach to evaluating the state of management of enterprise flow processes, which implies indicating the components, their characteristics and methods of research. The composition of indicators, on the basis of which it is possible to evaluate effectiveness of management of enterprise flow processes, has been determined. Grouping of such indicators based on the flow nature of enterprise processes has been performed. The grouping of indicators is justified by a pairwise determination of canonical correlations between the selected groups (the obtained high correlation coefficients confirmed the author’s systematization of indicators. It is shown that a specificity of the formation of a methodological approach to evaluating the state of management of enterprise flow processes requires expansion in the direction of aggregation of the results and determination of factors that influence effectiveness of flow processes management. The article carries out such aggregation using the factor analysis. Distribution of a set of objects into different classes according to the results of the cluster analysis has been presented. To obtain an integral estimation of effectiveness of flow processes management, the taxonomic index of a multidimensional object has been built. A peculiarity of the formed methodological approach to evaluating the state of management of enterprise flow processes is in the matrix correlation of integral indicators calculated on

  3. A methodological approach for designing and sequencing product families in Reconfigurable Disassembly Systems

    Directory of Open Access Journals (Sweden)

    Ignacio Eguia

    2011-10-01

    Full Text Available Purpose: A Reconfigurable Disassembly System (RDS represents a new paradigm of automated disassembly system that uses reconfigurable manufacturing technology for fast adaptation to changes in the quantity and mix of products to disassemble. This paper deals with a methodology for designing and sequencing product families in RDS. Design/methodology/approach: The methodology is developed in a two-phase approach, where products are first grouped into families and then families are sequenced through the RDS, computing the required machines and modules configuration for each family. Products are grouped into families based on their common features using a Hierarchical Clustering Algorithm. The optimal sequence of the product families is calculated using a Mixed-Integer Linear Programming model minimizing reconfigurability and operational costs. Findings: This paper is focused to enable reconfigurable manufacturing technologies to attain some degree of adaptability during disassembly automation design using modular machine tools. Research limitations/implications: The MILP model proposed for the second phase is similar to the well-known Travelling Salesman Problem (TSP and therefore its complexity grows exponentially with the number of products to disassemble. In real-world problems, which a higher number of products, it may be advisable to solve the model approximately with heuristics. Practical implications: The importance of industrial recycling and remanufacturing is growing due to increasing environmental and economic pressures. Disassembly is an important part of remanufacturing systems for reuse and recycling purposes. Automatic disassembly techniques have a growing number of applications in the area of electronics, aerospace, construction and industrial equipment. In this paper, a design and scheduling approach is proposed to apply in this area. Originality/value: This paper presents a new concept called Reconfigurable Disassembly System

  4. Methodological approach to assessment of organizational resources of the productive activity

    Directory of Open Access Journals (Sweden)

    Alexander Miller

    2017-05-01

    Full Text Available The purpose of this article is to solve the problem connected with development of theoretical and methodological provisions of formation of the assessment procedure of organizational resources of the productive activity. Theoretical results of our research are: improvement of the concept of development of organizational resources of the productive activity; identifying the impact of organizational resources on the productive activity; justification of the basic principles of formation of the assessment system of efficiency of the organizational resources' use. We proposed a unified methodological approach allowing to combine the complexity of assessment of both quantity of core resources of the productive activity and organizational resources, which significantly develops traditional systems of the productive activity management based on identifying quantitative parameters of the subsystems, their assessment, comparison and analysis. We also substantiated our opinion on assessment of organizational resources' values. It is focused on the development of the productive activity and allows to use the developed tools of the methodological approach for forecast assessment of the impact of the quantity of core resources, used in the productive activity, and organizational resources of the productive activity on the economic results of the enterprise.

  5. A multimedia approach for teaching human embryology: Development and evaluation of a methodology.

    Science.gov (United States)

    Moraes, Suzana Guimarães; Pereira, Luis Antonio Violin

    2010-12-20

    Human embryology requires students to understand the simultaneous changes in embryos, but students find it difficult to grasp the concepts presented and to visualise the related processes in three dimensions. The aims of this study have been to develop and evaluate new educational materials and a teaching methodology based on multimedia approaches to improve the comprehension of human development. The materials developed at the State University of Campinas include clinical histories, movies, animations, and ultrasound, as well as autopsy images from embryos and foetuses. The series of embryology lectures were divided into two parts. The first part of the series addressed the development of the body's structures, while in the second part, clinical history and the corresponding materials were shown to the students, who were encouraged to discuss the malformations. The teaching materials were made available on software used by the students in classes. At the end of the discipline, the material and methodology were evaluated with an attitudinal instrument, interviews, and knowledge examination. The response rate to the attitudinal instrument was 95.35%, and the response rate to the interview was 46%. The students approved of the materials and the teaching methodology (reliability of the attitudinal instrument was 0.9057). The exams showed that most students scored above 6.0. A multimedia approach proved useful for solving an important problem associated with teaching methods in many medical institutions: the lack of integration between basic sciences and clinical disciplines.

  6. Doing it the Gadamerian way--using philosophical hermeneutics as a methodological approach in nursing science.

    Science.gov (United States)

    Austgard, Kitt

    2012-12-01

    While several authors are referring to Gadamer's philosophy, the operationalization of his thinking into practical use in nursing science is less common. The goal of this paper is to systematize some of the basic key concepts in Gadamer's hermeneutics into a methodological approach to the interpretation of texts. This is a somewhat different approach to his work from those described in earlier commentaries and should be useful for nursing science. In this paper, Gadamer's hermeneutics is explored with a particular focus on some of the basic concepts of his philosophy. A four-step approach is proposed that may be used to develop a research plan in the Gadamerian hermeneutic tradition. Gadamer himself did not develop a method of interpretation, but elaborated upon the old hermeneutic tradition, of an inner fusion of subtilitas intelligendi (understanding), subtilitas explicandi (interpretation) and subtilitas applicandi (application). Hence, the analyses are not open and accessible, but inherent in the interpretation (auslegung). To use Gadamer's philosophy as a methodological approach, the interpreter must acquire a comprehensive understanding of the basic ideas and key concepts of his philosophy. These concepts may be used as a framework upon which to develop a research plan.

  7. Methodological Approach for Performing Human Reliability and Error Analysis in Railway Transportation System

    Directory of Open Access Journals (Sweden)

    Fabio De Felice

    2011-10-01

    Full Text Available Today, billions of dollars are being spent annually world wide to develop, manufacture, and operate transportation system such trains, ships, aircraft, and motor vehicles. Around 70 to 90 percent oftransportation crashes are, directly or indirectly, the result of human error. In fact, with the development of technology, system reliability has increased dramatically during the past decades, while human reliability has remained unchanged over the same period. Accordingly, human error is now considered as the most significant source of accidents or incidents in safety-critical systems. The aim of the paper is the proposal of a methodological approach to improve the transportation system reliability and in particular railway transportation system. The methodology presented is based on Failure Modes, Effects and Criticality Analysis (FMECA and Human Reliability Analysis (HRA.

  8. Testing the results of municipal mixed-use zoning ordinances: a novel methodological approach.

    Science.gov (United States)

    Cannon, Carol L; Thomas, Sue; Treffers, Ryan D; Paschall, Mallie J; Heumann, Lauren; Mann, Gregory W; Dunkell, Dashiell O; Nauenberg, Saskia

    2013-08-01

    Municipal mixed-use zoning (MUZ) is one public health strategy to create more walkable neighborhoods by reducing the separation of daily activities. This study uses a novel data-gathering methodology to evaluate municipal zoning ordinances in twenty-two California cities in conjunction with the walkability potential of resulting mixed-use zones, to explore the extent to which variations in uses mandated by MUZ ordinances are correlated with variations in walking opportunities. We find that, after controlling for population, socioeconomic status, and zone size, significant relationships exist between the range and precision of uses mandated by MUZ ordinances and the mixture and breadth of walking destinations in these zones. The study also demonstrates that analysis of municipal zoning codes and a novel data-gathering methodology yield valid data. The analysis of MUZ ordinances is a significant complement to other approaches to measuring walkability and can be used across cities.

  9. Enhancing the Benefit of the Chemical Mixture Methodology: A Report on Methodology Testing and Potential Approaches for Improving Performance

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Xiao-Ying; Yao, Juan; He, Hua; Glantz, Clifford S.; Booth, Alexander E.

    2012-01-01

    Extensive testing shows that the current version of the Chemical Mixture Methodology (CMM) is meeting its intended mission to provide conservative estimates of the health effects from exposure to airborne chemical mixtures. However, the current version of the CMM could benefit from several enhancements that are designed to improve its application of Health Code Numbers (HCNs) and employ weighting factors to reduce over conservatism.

  10. A methodology for the quantification of doctrine and materiel approaches in a capability-based assessment

    Science.gov (United States)

    Tangen, Steven Anthony

    Due to the complexities of modern military operations and the technologies employed on today's military systems, acquisition costs and development times are becoming increasingly large. Meanwhile, the transformation of the global security environment is driving the U.S. military's own transformation. In order to meet the required capabilities of the next generation without buying prohibitively costly new systems, it is necessary for the military to evolve across the spectrum of doctrine, organization, training, materiel, leadership and education, personnel, and facilities (DOTMLPF). However, the methods for analyzing DOTMLPF approaches within the early acquisition phase of a capability-based assessment (CBA) are not as well established as the traditional technology design techniques. This makes it difficult for decision makers to decide if investments should be made in materiel or non-materiel solutions. This research develops an agent-based constructive simulation to quantitatively assess doctrine alongside materiel approaches. Additionally, life-cycle cost techniques are provided to enable a cost-effectiveness trade. These techniques are wrapped together in a decision-making environment that brings crucial information forward so informed and appropriate acquisition choices can be made. The methodology is tested on a future unmanned aerial vehicle design problem. Through the implementation of this quantitative methodology on the proof-of-concept study, it is shown that doctrinal changes including fleet composition, asset allocation, and patrol pattern were capable of dramatic improvements in system effectiveness at a much lower cost than the incorporation of candidate technologies. Additionally, this methodology was able to quantify the precise nature of strong doctrine-doctrine and doctrine-technology interactions which have been observed only qualitatively throughout military history. This dissertation outlines the methodology and demonstrates how potential

  11. AN APPROACH TO DESIGN ADVANCED STANDARD ENCRYPTION ALGORITHM USING HARDWARE / SOFTWARE CO-DESIGN METHODOLOGY

    Directory of Open Access Journals (Sweden)

    MEGHANA A. HASAMNIS

    2012-05-01

    Full Text Available An Advanced Standard Encryption Algorithm (AES is widely used in modern consumer electronicproducts for security. The IEEE 802.15.4 Low-Rate wireless sensor networks also use AES algorithm wherelow power consumption is the priority. To reduce the time taken for encryption of huge data, the algorithm hasto be implemented in hardware. To meet the requirement for low area the algorithm has to be implemented insoftware. Hence, a balance has to be achieved between hardware and software implementations in terms of areaand speed, so as to improve the overall performance of the system. Also with the co-design methodology totalthermal power dissipation is reduced. In this paper, 128 bit AES algorithm is implemented with hardware incombination with software using Altera NIOS II Processor platform. Altera’s Quartus II environment is used fordesign of the system. Cyclone II FPGA is used as a development platform. Software program is written in C language. NIOS II ntegrated Development Environment (IDE is used to integrate hardware and software together. By adopting hardware / software co-design methodology for implementation of AES, results show that a onsiderable improvement in speed can be achieved as compared to software only approach. Further, the significant reduction in area is achieved as compared to hardware only approach. By the approach of co-design an optimized design in terms of speed and area is achieved and also the thermal power dissipation is reduced

  12. Computational simulation methodologies for mechanobiological modelling: a cell-centred approach to neointima development in stents.

    Science.gov (United States)

    Boyle, C J; Lennon, A B; Early, M; Kelly, D J; Lally, C; Prendergast, P J

    2010-06-28

    The design of medical devices could be very much improved if robust tools were available for computational simulation of tissue response to the presence of the implant. Such tools require algorithms to simulate the response of tissues to mechanical and chemical stimuli. Available methodologies include those based on the principle of mechanical homeostasis, those which use continuum models to simulate biological constituents, and the cell-centred approach, which models cells as autonomous agents. In the latter approach, cell behaviour is governed by rules based on the state of the local environment around the cell; and informed by experiment. Tissue growth and differentiation requires simulating many of these cells together. In this paper, the methodology and applications of cell-centred techniques--with particular application to mechanobiology--are reviewed, and a cell-centred model of tissue formation in the lumen of an artery in response to the deployment of a stent is presented. The method is capable of capturing some of the most important aspects of restenosis, including nonlinear lesion growth with time. The approach taken in this paper provides a framework for simulating restenosis; the next step will be to couple it with more patient-specific geometries and quantitative parameter data.

  13. A problem-based approach to teaching research methodology to medical graduates in Iran

    Directory of Open Access Journals (Sweden)

    Mehrdad Jalalian Hosseini

    2009-08-01

    Full Text Available Physicians are reticent to participate in research projects for avariety of reasons. Facilitating the active involvement ofdoctors in research projects is a high priority for the IranianBlood Transfusion Organization (IBTO. A one-month trainingcourse on research methodology was conducted for a groupof physicians in Mashhad, in northeast Iran. The participantswere divided in ten groups. They prepared a researchproposal under the guidance of a workshop leader. Thequality of the research proposals, which were prepared by allparticipants, went beyond our expectations. All of theresearch proposals were relevant to blood safety. In this briefreport we describe our approach.

  14. APPROACHES TO DEVELOPMENT OF THE METHODOLOGY OF RECONSTRUCTION OF WASTE WATER TREATMENT PLANTS

    Directory of Open Access Journals (Sweden)

    Gogina Elena Sergeevna

    2012-10-01

    WWTPs fail to perform proper treatment due to their being worn-out and obsolete. However a tougher legislation accelerates their reconstruction. Approaches to the WWTP reconstruction should demonstrate a strong economic and technological base. The author proposes a new algorithm for their reconstruction. A sensible combination of the principles of WWTP restructuring, development of new fine wastewater cleaning methods, and assimilation of new materials and chemical agents will help resolve the vital problem of waste water discharge into Russia's water bodies. This is the first methodology of reconstruction of WWTPs developed on the basis of the above concept and supported by practical implementation.

  15. Cyclical convergence of Central and Eastern European countries to the Euro area core. New methodological approach

    Directory of Open Access Journals (Sweden)

    Ileana ALEXE

    2013-04-01

    Full Text Available The current paper develops an analysis on the degree of business cycle convergence of the new member states of the EU towards the Euro area core (Germany, France, Italy, Belgium, Netherlands and Luxembourg during 1996 – 2010.Unlike the previous research, the study takes into consideration the similarity of cycles, and not their synchronization. Furthermore, from the methodological point of view, it explores the use of survey indicators in the analysis of the cycles, thus in addition to the traditional approach that employs the GDP. The results obtained through clusterization show that the degree of convergence towards Euro area core remains modest.

  16. A Methodological Approach to User Evaluation and Assessment of a Virtual Environment Hangout

    Directory of Open Access Journals (Sweden)

    Marco Pasin

    2015-08-01

    Full Text Available Innovation in virtual reality and motion sensing devices is pushing the development of virtual communication platforms towards completely immersive scenarios, which require full user interaction and create complex sensory experiences. This evolution influences user experiences and creates new paradigms for interaction, leading to an increased importance of user evaluation and assessment on new systems interfaces and usability, to validate platform design and development from the users’ point of view. The REVERIE research project aims to develop a virtual environment service for realistic inter-personal interaction. This paper describes the design challenges faced during the development process of user interfaces and the adopted methodological approach to user evaluation and assessment.

  17. A Methodological Approach for Assessing Amplified Reflection Distributed Denial of Service on the Internet of Things.

    Science.gov (United States)

    Costa Gondim, João José; de Oliveira Albuquerque, Robson; Clayton Alves Nascimento, Anderson; García Villalba, Luis Javier; Kim, Tai-Hoon

    2016-11-04

    Concerns about security on Internet of Things (IoT) cover data privacy and integrity, access control, and availability. IoT abuse in distributed denial of service attacks is a major issue, as typical IoT devices' limited computing, communications, and power resources are prioritized in implementing functionality rather than security features. Incidents involving attacks have been reported, but without clear characterization and evaluation of threats and impacts. The main purpose of this work is to methodically assess the possible impacts of a specific class-amplified reflection distributed denial of service attacks (AR-DDoS)-against IoT. The novel approach used to empirically examine the threat represented by running the attack over a controlled environment, with IoT devices, considered the perspective of an attacker. The methodology used in tests includes that perspective, and actively prospects vulnerabilities in computer systems. This methodology defines standardized procedures for tool-independent vulnerability assessment based on strategy, and the decision flows during execution of penetration tests (pentests). After validation in different scenarios, the methodology was applied in amplified reflection distributed denial of service (AR-DDoS) attack threat assessment. Results show that, according to attack intensity, AR-DDoS saturates reflector infrastructure. Therefore, concerns about AR-DDoS are founded, but expected impact on abused IoT infrastructure and devices will be possibly as hard as on final victims.

  18. A Methodological Approach for Assessing Amplified Reflection Distributed Denial of Service on the Internet of Things

    Directory of Open Access Journals (Sweden)

    João José Costa Gondim

    2016-11-01

    Full Text Available Concerns about security on Internet of Things (IoT cover data privacy and integrity, access control, and availability. IoT abuse in distributed denial of service attacks is a major issue, as typical IoT devices’ limited computing, communications, and power resources are prioritized in implementing functionality rather than security features. Incidents involving attacks have been reported, but without clear characterization and evaluation of threats and impacts. The main purpose of this work is to methodically assess the possible impacts of a specific class–amplified reflection distributed denial of service attacks (AR-DDoS–against IoT. The novel approach used to empirically examine the threat represented by running the attack over a controlled environment, with IoT devices, considered the perspective of an attacker. The methodology used in tests includes that perspective, and actively prospects vulnerabilities in computer systems. This methodology defines standardized procedures for tool-independent vulnerability assessment based on strategy, and the decision flows during execution of penetration tests (pentests. After validation in different scenarios, the methodology was applied in amplified reflection distributed denial of service (AR-DDoS attack threat assessment. Results show that, according to attack intensity, AR-DDoS saturates reflector infrastructure. Therefore, concerns about AR-DDoS are founded, but expected impact on abused IoT infrastructure and devices will be possibly as hard as on final victims.

  19. A Methodological Approach for Assessing Amplified Reflection Distributed Denial of Service on the Internet of Things

    Science.gov (United States)

    Costa Gondim, João José; de Oliveira Albuquerque, Robson; Clayton Alves Nascimento, Anderson; García Villalba, Luis Javier; Kim, Tai-Hoon

    2016-01-01

    Concerns about security on Internet of Things (IoT) cover data privacy and integrity, access control, and availability. IoT abuse in distributed denial of service attacks is a major issue, as typical IoT devices’ limited computing, communications, and power resources are prioritized in implementing functionality rather than security features. Incidents involving attacks have been reported, but without clear characterization and evaluation of threats and impacts. The main purpose of this work is to methodically assess the possible impacts of a specific class–amplified reflection distributed denial of service attacks (AR-DDoS)–against IoT. The novel approach used to empirically examine the threat represented by running the attack over a controlled environment, with IoT devices, considered the perspective of an attacker. The methodology used in tests includes that perspective, and actively prospects vulnerabilities in computer systems. This methodology defines standardized procedures for tool-independent vulnerability assessment based on strategy, and the decision flows during execution of penetration tests (pentests). After validation in different scenarios, the methodology was applied in amplified reflection distributed denial of service (AR-DDoS) attack threat assessment. Results show that, according to attack intensity, AR-DDoS saturates reflector infrastructure. Therefore, concerns about AR-DDoS are founded, but expected impact on abused IoT infrastructure and devices will be possibly as hard as on final victims. PMID:27827931

  20. Project INTEGRATE - a common methodological approach to understand integrated health care in Europe

    Directory of Open Access Journals (Sweden)

    Lucinda Cash-Gibson

    2014-12-01

    Full Text Available Background: The use of case studies in health services research has proven to be an excellent methodology for gaining in-depth understanding of the organisation and delivery of health care. This is particularly relevant when looking at the complexity of integrated healthcare programmes, where multifaceted interactions occur at the different levels of care and often without a clear link between the interventions (new and/or existing and their impact on outcomes (in terms of patients health, both patient and professional satisfaction and cost-effectiveness. Still, integrated care is seen as a core strategy in the sustainability of health and care provision in most societies in Europe and beyond. More specifically, at present, there is neither clear evidence on transferable factors of integrated care success nor a method for determining how to establish these specific success factors. The drawback of case methodology in this case, however, is that the in-depth results or lessons generated are usually highly context-specific and thus brings the challenge of transferability of findings to other settings, as different health care systems and different indications are often not comparable. Project INTEGRATE, a European Commission-funded project, has been designed to overcome these problems; it looks into four chronic conditions in different European settings, under a common methodology framework (taking a mixed-methods approach to try to overcome the issue of context specificity and limited transferability. The common methodological framework described in this paper seeks to bring together the different case study findings in a way that key lessons may be derived and transferred between countries, contexts and patient-groups, where integrated care is delivered in order to provide insight into generalisability and build on existing evidence in this field.Methodology: To compare the different integrated care experiences, a mixed-methods approach has

  1. Project INTEGRATE - a common methodological approach to understand integrated health care in Europe

    Directory of Open Access Journals (Sweden)

    Lucinda Cash-Gibson

    2014-12-01

    Full Text Available Background: The use of case studies in health services research has proven to be an excellent methodology for gaining in-depth understanding of the organisation and delivery of health care. This is particularly relevant when looking at the complexity of integrated healthcare programmes, where multifaceted interactions occur at the different levels of care and often without a clear link between the interventions (new and/or existing and their impact on outcomes (in terms of patients health, both patient and professional satisfaction and cost-effectiveness. Still, integrated care is seen as a core strategy in the sustainability of health and care provision in most societies in Europe and beyond. More specifically, at present, there is neither clear evidence on transferable factors of integrated care success nor a method for determining how to establish these specific success factors. The drawback of case methodology in this case, however, is that the in-depth results or lessons generated are usually highly context-specific and thus brings the challenge of transferability of findings to other settings, as different health care systems and different indications are often not comparable. Project INTEGRATE, a European Commission-funded project, has been designed to overcome these problems; it looks into four chronic conditions in different European settings, under a common methodology framework (taking a mixed-methods approach to try to overcome the issue of context specificity and limited transferability. The common methodological framework described in this paper seeks to bring together the different case study findings in a way that key lessons may be derived and transferred between countries, contexts and patient-groups, where integrated care is delivered in order to provide insight into generalisability and build on existing evidence in this field. Methodology: To compare the different integrated care experiences, a mixed-methods approach has

  2. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect

    DEFF Research Database (Denmark)

    Triantafyllou, Evangelia; Kofoed, Lise; Purwins, Hendrik

    2016-01-01

    , while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators......One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class...... through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM) are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens...

  3. Eco-efficiency of agricultural water systems: Methodological approach and assessment at meso-level scale.

    Science.gov (United States)

    Todorovic, Mladen; Mehmeti, Andi; Scardigno, Alessandra

    2016-01-01

    This study presents a methodological framework for the meso-level eco-efficiency assessment of agricultural water systems using a life-cycle system-based approach. The methodology was applied to the Sinistra Ofanto irrigation scheme, located in Southern Italy, where about 28,165 ha are under irrigation. The environmental performance of the system was evaluated through a set of selected mid-point environmental impact categories while the economic performance was measured using the total value added to the system's final products due to water use and the adopted management practices. Both economic performance and environmental performance were measured at different stages and for each stakeholder in the value chain. A distinction was made between foreground and background systems referring, respectively, to the processes that occurred inside the water system boundaries and those used for the production of supplementary resources. The analysis revealed that the major environmental burdens are: i) the freshwater resource depletion (i.e. excessive groundwater pumping), ii) climate change (i.e. direct emissions due to fertilizer use and diesel combustion), and iii) eutrophication (as a result of excessive application of N and P fertilizers). A considerable impact was observed on the background system where energy, fuel and agrochemicals were produced thereby confirming the prominent role of background processes in the comprehensive eco-efficiency assessment. The presented methodology aimed at the quantitative assessment of the eco-efficiency level rather than at the identification of the most affected environmental category. Hence, the results can be used to compare the performance of the system from one year to the next, among different stakeholders (water users) and/or to assess the impact of adopting innovative technologies and management practices. Moreover, the presented approach is useful for comparing the performance among different agricultural water systems and

  4. A methodological approach to characterize the resilience of aquatic ecosystems with application to Lake Annecy, France

    Science.gov (United States)

    Pinault, J.-L.; Berthier, F.

    2007-01-01

    We propose a methodological approach to characterize the resilience of aquatic ecosystems with respect to the evolution of environmental parameters as well as their aptitude to adapt to forcings. This method that is applied to Lake Annecy, France, proceeds in three stages. First, according to the depth, variations of physicochemical parameters versus time are separated into three components related to (1) energy transfer through the surface of the lake, (2) the flow of rivers and springs that feed the lake, and (3) long-term evolution of the benthic zone as a consequence of mineral and organic matter loads. Second, dynamics of the lake are deduced by analyzing the physicochemical parameter components related to the three boundary conditions. Third, a stochastic process associated with the transfer models aims to characterize the resilience of the lakes according to forcings. For Lake Annecy, whose dynamics are representative of oligotrophic stratified lakes controlled by decarbonation processes where turnover and mixing occurring once a year in winter, the major consequence is the impoverishment of dissolved oxygen in deep water in autumn due to a temperature increase of the surface water in summer. The simulation raises relevant questions about whether a connection exists between physicochemical parameters and global warming, which should not induce harmful consequences on water quality and biodiversity in deep water. This methodological approach is general since it does not use any physical conceptual model to predict the hydrosystem behavior but uses directly observed data.

  5. Textbook research and the pedagogical past: An outline of contemporary methodological approaches

    Directory of Open Access Journals (Sweden)

    Ilić-Rajković Aleksandra V.

    2016-01-01

    Full Text Available The paper presents two contemporary methodological approaches to the historicalpedagogical study of textbooks, based on a concept of textbooks underpinned by hermeneutics and critical theory. In the first part of the paper, a textbook is defined as a medium of socio-cultural knowledge representing an image of a given society that is in many ways filtered, restructured and controlled. The paper considers the implications of such a position for the study of the pedagogical past. The main section of the paper presents methodological guidelines for a broader understanding of textbooks based on the above-mentioned theoretical concepts. It is suggested that the study of textbooks should take into consideration its contextual determinants. This involves, on the one hand, collecting data about the processes of textbook creation, that is, about the production within which the selection, legitimization and pedagogical-didactic transformation of socio-cultural knowledge occurs, and also, on the other hand, collecting data about the processes of textbook use, i.e. the transmission and reception of knowledge. In addition, guidelines for the study of internal textbook organization are given. The conclusion of the paper highlights the importance of the approaches presented, and points to a number of thematic areas for studying the pedagogical past which are opened up through the adoption of the presented views on textbooks presented in the paper.

  6. Machining Performance Study on Metal Matrix Composites-A Response Surface Methodology Approach

    Directory of Open Access Journals (Sweden)

    A. Srinivasan

    2012-01-01

    Full Text Available Problem statement: Metal Matrix Composites (MMC have become a leading material among composite materials and in particular, particle reinforced aluminum MMCs have received considerable attention due to their excellent engineering properties. These materials are known as the difficult-to-machine materials because of the hardness and abrasive nature of reinforcement element-like Alumina (Al2O3. Approach: In this study, an attempt has been made to model the machinability evaluation through the response surface methodology in machining of homogenized 10% micron Al2O3 LM25 Al MMC manufactured through stir casting method. Results: The combined effects of three machining parameters including cutting speed (s, feed rate (f and depth of cut (d on the basis of three performance characteristics of tool wear (VB, surface Roughness (Ra and cutting Force (Fz were investigated. The contour plots were generated to study the effect of process parameters as well as their interactions. Conclusion: The process parameters are optimized using desirability-based approach response surface methodology.

  7. [METHODOLOGICAL APPROACHES TO DEFINING CRITERIA FOR ACCREDITATION OF SPECIALISTS (IN CASE OF MEDICAL PARASITOLOGISTS)].

    Science.gov (United States)

    Astanina, S Yu; Dovgalev, A S; Andreeva, N D

    2015-01-01

    In 2016, provision is made for the transition for an accreditation system for all health workers to have individual permits for specific kinds of medical activities. Regular accreditation of health workers is one of the constituents of medical education, which is being intensively elaborated by the Ministry of Health of Russia jointly with a professional community by the module principle of using an accumulation system of valid credits. Despite the fact that higher educational establishments belong to different agencies, educational programs for physicians, criteria and procedures for their accreditation must be uniform. In this connection, there is today's challenge of methodological and methodical approaches to defining criteria for the accreditation of specialists of healthcare facilities of the Ministry of Health of Russia, bodies and institutions of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare. In the context of systemic and functional methodological approaches, the paper shows a procedure for defining criteria for the accreditation of specialists (in case of medical parasitologists).

  8. IoT-Based Information System for Healthcare Application: Design Methodology Approach

    Directory of Open Access Journals (Sweden)

    Damian Dziak

    2017-06-01

    Full Text Available Over the last few decades, life expectancy has increased significantly. However, elderly people who live on their own often need assistance due to mobility difficulties, symptoms of dementia or other health problems. In such cases, an autonomous supporting system may be helpful. This paper proposes the Internet of Things (IoT-based information system for indoor and outdoor use. Since the conducted survey of related works indicated a lack of methodological approaches to the design process, therefore a Design Methodology (DM, which approaches the design target from the perspective of the stakeholders, contracting authorities and potential users, is introduced. The implemented solution applies the three-axial accelerometer and magnetometer, Pedestrian Dead Reckoning (PDR, thresholding and the decision trees algorithm. Such an architecture enables the localization of a monitored person within four room-zones with accuracy; furthermore, it identifies falls and the activities of lying, standing, sitting and walking. Based on the identified activities, the system classifies current activities as normal, suspicious or dangerous, which is used to notify the healthcare staff about possible problems. The real-life scenarios validated the high robustness of the proposed solution. Moreover, the test results satisfied both stakeholders and future users and ensured further cooperation with the project.

  9. Methodology for Assessing the Quality of Agribusiness Activity Based on the Environmentally Responsible Approach

    Directory of Open Access Journals (Sweden)

    Anna Antonovna Anfinogentova

    2017-06-01

    Full Text Available The article is devoted to the research and development of quality evaluation methods of agro-industrial enterprises activity in the regional economy with the use of the ecological approach. The hypothesis of the study is that the activity of the economic entities (as well as of agribusiness must be assessed not only in the context of economic efficiency and effectiveness, but also in the context of environmental ethics and environmental aggression. As the initial data, we have used the indicators of economic statistics of Russian agrarian-oriented regions, as well as the data received from management reporting on the sample of enterprises of three regions (the Belgorod and Moscow regions, Krasnodar Territory. The article offers the economic and mathematical approach for measuring the level of the environmental responsibility of agro-industrial enterprises on the basic formula of the Mandelbrot set and statistical indicator of Hurst. Our scientific contribution is the development of a modified methodology for assessing the quality of the activity of agro-industrial enterprises using the parameter characterizing the level of environmental ethics and environmental aggression of these entities. The main result of the study is the approbation of the method, which has shown its practical applicability and relative coherence with certain indicators of regional ecological statistics. The proposed method is characterized by the integration of the different mathematical approaches and as an adaptive assessment tool that can be used to assess the quality of the activity of both agro-industrial enterprises and enterprises of other industries and fields of the economy. In the further works, the authors plan to develop methodological approaches to the assessment of the quality of agro-industrial products. At the same time, the main attention will be paid to the ecological and social component of the quality.

  10. From concepts, theory, and evidence of heterogeneity of treatment effects to methodological approaches: a primer.

    Science.gov (United States)

    Willke, Richard J; Zheng, Zhiyuan; Subedi, Prasun; Althin, Rikard; Mullins, C Daniel

    2012-12-13

    Implicit in the growing interest in patient-centered outcomes research is a growing need for better evidence regarding how responses to a given intervention or treatment may vary across patients, referred to as heterogeneity of treatment effect (HTE). A variety of methods are available for exploring HTE, each associated with unique strengths and limitations. This paper reviews a selected set of methodological approaches to understanding HTE, focusing largely but not exclusively on their uses with randomized trial data. It is oriented for the "intermediate" outcomes researcher, who may already be familiar with some methods, but would value a systematic overview of both more and less familiar methods with attention to when and why they may be used. Drawing from the biomedical, statistical, epidemiological and econometrics literature, we describe the steps involved in choosing an HTE approach, focusing on whether the intent of the analysis is for exploratory, initial testing, or confirmatory testing purposes. We also map HTE methodological approaches to data considerations as well as the strengths and limitations of each approach. Methods reviewed include formal subgroup analysis, meta-analysis and meta-regression, various types of predictive risk modeling including classification and regression tree analysis, series of n-of-1 trials, latent growth and growth mixture models, quantile regression, and selected non-parametric methods. In addition to an overview of each HTE method, examples and references are provided for further reading.By guiding the selection of the methods and analysis, this review is meant to better enable outcomes researchers to understand and explore aspects of HTE in the context of patient-centered outcomes research.

  11. From concepts, theory, and evidence of heterogeneity of treatment effects to methodological approaches: a primer

    Directory of Open Access Journals (Sweden)

    Willke Richard J

    2012-12-01

    Full Text Available Abstract Implicit in the growing interest in patient-centered outcomes research is a growing need for better evidence regarding how responses to a given intervention or treatment may vary across patients, referred to as heterogeneity of treatment effect (HTE. A variety of methods are available for exploring HTE, each associated with unique strengths and limitations. This paper reviews a selected set of methodological approaches to understanding HTE, focusing largely but not exclusively on their uses with randomized trial data. It is oriented for the “intermediate” outcomes researcher, who may already be familiar with some methods, but would value a systematic overview of both more and less familiar methods with attention to when and why they may be used. Drawing from the biomedical, statistical, epidemiological and econometrics literature, we describe the steps involved in choosing an HTE approach, focusing on whether the intent of the analysis is for exploratory, initial testing, or confirmatory testing purposes. We also map HTE methodological approaches to data considerations as well as the strengths and limitations of each approach. Methods reviewed include formal subgroup analysis, meta-analysis and meta-regression, various types of predictive risk modeling including classification and regression tree analysis, series of n-of-1 trials, latent growth and growth mixture models, quantile regression, and selected non-parametric methods. In addition to an overview of each HTE method, examples and references are provided for further reading. By guiding the selection of the methods and analysis, this review is meant to better enable outcomes researchers to understand and explore aspects of HTE in the context of patient-centered outcomes research.

  12. Contemporary strategic management approach in the defense system by U.S. methodology concept

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    Veselin I. Mrdak

    2013-12-01

    Full Text Available The paper wants to emphasize the importance of contemporary strategic management approachs in the defense system. Displays the work of American author Leslie Lewis and C. Robert Roll "Strategy-to- tasks: a methodology for resource allocation and management". It were used by parts of the discussion above, in order to describe the strategy-to-tasks methodology for planning, programming and budgeting system (PPBS. In developed Western countries adopted some elements of strategic management to determine and monitor the execution of strategic plans in the defense system. This trend is spreading to other countries as a result of the necessity of obeying certain methodological and technological achievements. The uncritical acceptance of a strategic management approach can cause great confusion and problems, and the terminology and scientific explanation for this trend is of great importance. Introduction PPBS is a resource management framework based on force planning concept. It was developed at the lRand Company during the late eighties and is adapted to the special needs of several DoD organization. The planning, programming and budgeting system (PPBS PPBS is DoD`ş primary system for planning and managing defense resources. It links the overall U.S. national security strategy to specific programs. It was designed to facilitate fiscally-constrained planning, programming and budgeting in terms of complete programs (i.e. forces and systems rather than through artificial budget categories. The goal is to determine forces, systems and program costs. Strategy-to-tasks and the PPBS The Strategy-To-Tasks methodology, regardless of its application, it must be consistent and supportive of each phase of the PPBS. This section describes the basics frameworks of which are adapted to resource allocation and management activities for the Special Operations Command (USSOCOM. The authors have used it during the various phases of the PPBS. The National Security

  13. A new methodology for building energy benchmarking: An approach based on clustering concept and statistical models

    Science.gov (United States)

    Gao, Xuefeng

    Though many building energy benchmarking programs have been developed during the past decades, they hold certain limitations. The major concern is that they may cause misleading benchmarking due to not fully considering the impacts of the multiple features of buildings on energy performance. The existing methods classify buildings according to only one of many features of buildings -- the use type, which may result in a comparison between two buildings that are tremendously different in other features and not properly comparable as a result. This research aims to tackle this challenge by proposing a new methodology based on the clustering concept and statistical analysis. The clustering concept, which reflects on machine learning algorithms, classifies buildings based on a multi-dimensional domain of building features, rather than the single dimension of use type. Buildings with the greatest similarity of features that influence energy performance are classified into the same cluster, and benchmarked according to the centroid reference of the cluster. Statistical analysis is applied to find the most influential features impacting building energy performance, as well as provide prediction models for the new design energy consumption. The proposed methodology as applicable to both existing building benchmarking and new design benchmarking was discussed in this dissertation. The former contains four steps: feature selection, clustering algorithm adaptation, results validation, and interpretation. The latter consists of three parts: data observation, inverse modeling, and forward modeling. The experimentation and validation were carried out for both perspectives. It was shown that the proposed methodology could account for the total building energy performance and was able to provide a more comprehensive approach to benchmarking. In addition, the multi-dimensional clustering concept enables energy benchmarking among different types of buildings, and inspires a new

  14. [Psychological and psychosocial autopsy on suicide among the elderly: a methodological approach].

    Science.gov (United States)

    Cavalcante, Fátima Gonçalves; Minayo, Maria Cecília de Souza; Meneghel, Stela Nazareth; Silva, Raimunda Magalhães da; Gutierrez, Denise Machado Duran; Conte, Marta; Figueiredo, Ana Elisa Bastos; Grubits, Sonia; Cavalcante, Ana Célia Sousa; Mangas, Raimunda Matilde do Nascimento; Vieira, Luiza Jane Eyre de Souza; Moreira, Gracyelle Alves Remigio

    2012-08-01

    The article analyzes the quality and consistency of a semi-structured interview script, adapted for the study on suicide among elderly people, and presents the psychological and psychosocial autopsy method, which is the result of application of this instrument. The objective is to demonstrate how the in-depth interview and subsequent data organization and analyses were tested and improved by a network of researchers from eight regions in Brazil. Evaluation of the method was conducted before and after the application of the instruments to collect, systematize and analyze the data. This methodology was applied in 51 cases of elderly people who committed suicide in ten Brazilian municipalities. The study did more than just collect data with scientific rigor, since it also verified the consistency of the instrument used and the applicability of the method. The improved script and the instructions of how to apply and analyze it are thus presented here. The results reveal the rigor and credibility of this methodological approach tested and qualified by a multidisciplinary and inter-institutional procedure.

  15. A methodological approach of estimating resistance to flow under unsteady flow conditions

    Science.gov (United States)

    Mrokowska, M. M.; Rowiński, P. M.; Kalinowska, M. B.

    2015-10-01

    This paper presents an evaluation and analysis of resistance parameters: friction slope, friction velocity and Manning coefficient in unsteady flow. The methodology to enhance the evaluation of resistance by relations derived from flow equations is proposed. The main points of the methodology are (1) to choose a resistance relation with regard to a shape of a channel and (2) type of wave, (3) to choose an appropriate method to evaluate slope of water depth, and (4) to assess the uncertainty of result. In addition to a critical analysis of existing methods, new approaches are presented: formulae for resistance parameters for a trapezoidal channel, and a translation method instead of Jones' formula to evaluate the gradient of flow depth. Measurements obtained from artificial dam-break flood waves in a small lowland watercourse have made it possible to apply the method and to analyse to what extent resistance parameters vary in unsteady flow. The study demonstrates that results of friction slope and friction velocity are more sensitive to applying simplified formulae than the Manning coefficient (n). n is adequate as a flood routing parameter but may be misleading when information on trend of resistance with flow rate is crucial. Then friction slope or friction velocity seems to be better choice.

  16. Problem of Methodological Approach in Historical School of Philosophy of Science

    Directory of Open Access Journals (Sweden)

    Albinas Plėšnys

    2011-04-01

    Full Text Available The normative philosophy of science represents inadequate image of scientific development, and its methodological significance is questionable. The followers of historical school of philosophy of science propose a new conception of aims and tasks of philosophy of science. Investigation of convictions and images that were accepted during certain historical periods rather than logical analysis of knowledge becomes the main problem in historical school of philosophy of science. This approach changes the old methodological status of philosophy of science. But the new point of view isn’t without shortcomings either. The main disadvantage of the new position is presumption that scientific knowledge functions as an autonomous system, irrespective of philosophical or theological context, and that only cognitive values are significant in the scientific research process.  From our point of view analysis of scientific knowledge without consideration of metaphysical context is false because science is subordinated to this context. Changes of metaphysical scientific research programmes rather than those of paradigms or scientific research programmes take place in the process of scientific development. 

  17. Attitudes of Korean adults towards human dignity: a Q methodology approach.

    Science.gov (United States)

    Jo, Kae Hwa; An, Gyeong-Ju; Doorenbos, Ardith Z

    2012-06-01

    The aim of this study was to identify the perceived attitudes of Korean adults towards human dignity in order to determine the relationship of human dignity to its social and cultural background. The Q methodology research technique was used to explore perceived attitude typology on the basis of the respondents' ranking order for different statements. A convenience sampling method was used to select 40 Korean adults who were interested in human dignity to create statements. From the questionnaires, in-depth interviews, and a literature review, a total of 158 statements was obtained. The final 34 Q samples were selected from a review by two nursing professors and a Q methodology expert. Moreover, 38 respondents participated as P samples by sorting 34 Q statements on a nine-point normal distribution scale. The data were analyzed by using the QUANL software package. The following four types of attitudes about human dignity were identified in Korea: a happiness-oriented-self-pursuit type, relationship-oriented-self-recognition type, reflection-oriented-self-unification type, and discrimination-oriented-self-maintenance type. The results indicate that approaches to developing human dignity education need to take this typology into account and the characteristics of the participants who fall into each category. These results provide general guidelines to understand Korean values for professional practice in various healthcare settings. © 2011 The Authors. Japan Journal of Nursing Science © 2011 Japan Academy of Nursing Science.

  18. Systems approaches to animal disease surveillance and resource allocation: methodological frameworks for behavioral analysis.

    Science.gov (United States)

    Rich, Karl M; Denwood, Matthew J; Stott, Alistair W; Mellor, Dominic J; Reid, Stuart W J; Gunn, George J

    2013-01-01

    While demands for animal disease surveillance systems are growing, there has been little applied research that has examined the interactions between resource allocation, cost-effectiveness, and behavioral considerations of actors throughout the livestock supply chain in a surveillance system context. These interactions are important as feedbacks between surveillance decisions and disease evolution may be modulated by their contextual drivers, influencing the cost-effectiveness of a given surveillance system. This paper identifies a number of key behavioral aspects involved in animal health surveillance systems and reviews some novel methodologies for their analysis. A generic framework for analysis is discussed, with exemplar results provided to demonstrate the utility of such an approach in guiding better disease control and surveillance decisions.

  19. The game as strategy for approach to sexuality with adolescents: theoretical-methodological reflections.

    Science.gov (United States)

    Souza, Vânia de; Gazzinelli, Maria Flávia; Soares, Amanda Nathale; Fernandes, Marconi Moura; Oliveira, Rebeca Nunes Guedes de; Fonseca, Rosa Maria Godoy Serpa da

    2017-04-01

    To describe the Papo Reto [Straight Talk] game and reflect on its theoretical-methodological basis. Analytical study on the process of elaboration of the Papo Reto online game, destined to adolescents aged 15-18 years, with access to the Game between 2014 and 2015. the interactions of 60 adolescents from Belo Horizonte and São Paulo constituted examples of the potentialities of the Game to favor the approach to sexuality with adolescents through simulation of reality, invention and interaction. Based on those potentialities, four thinking categories were discussed: the game as pedagogic device; the game as simulation of realities; the game as device for inventive learning; and the game empowering the interaction. By permitting that the adolescents take risks on new ways, the Game allows them to become creative and active in the production of senses, in the creation of their discourses and in the ways of thinking, feeling and acting in the sexuality field.

  20. Methodological lessons in neurophenomenology: Review of a baseline study and recommendations for research approaches

    Directory of Open Access Journals (Sweden)

    Patricia eBockelman

    2013-10-01

    Full Text Available Neurophenomenological methods integrate objective and subjective data in ways that retain the statistical power of established disciplines (like cognitive science while embracing the value of first-person reports of experience. The present paper positions neurophenomenology as an approach that pulls from traditions of cognitive science but includes techniques that are challenging for cognitive science in some ways. A baseline study is reviewed for lessons learned, that is, the potential methodological improvements that will support advancements in understanding consciousness and cognition using neurophenomenology. These improvements, we suggest, include (1 addressing issues of interdisciplinarity by purposefully and systematically creating and maintaining shared mental models among research team members; (2 making sure that neurophenomenological experiments include high standards of experimental design and execution to achieve variable control, reliability, generalizability, and replication of results; and (3 conceiving of phenomenological interview techniques as placing the impetus on the interviewer in interaction with the experimental subject.

  1. Dancing with the Wind: A Methodological Approach to Researching Women's Spirituality around Menstruation and Birth

    Directory of Open Access Journals (Sweden)

    Sharon Moloney

    2007-03-01

    Full Text Available Research into spirituality is by definition problematic. In an evidence-based culture, how is a concept like spirituality defined and measured? Through her doctoral dissertation, the author seeks to illuminate dimensions of female spirituality connected with the processes of menstruation and birth. In Western industrialized culture, these processes are regarded as medical concerns. Reframing the spiritual significance of menses, the author explores the links between attitudes toward menstruation and spirituality, and women's birth experiences. The lack of research and literature about the spirituality of menstruation, or the spiritual care of the birthing woman denotes a vacuum in both theory and practice. The author presents her methodological approach to resolving the dilemma of how to research the elusive concept of female spirituality—an endeavor akin to attempting to lasso the wind! Through a combination of autoethnography, focus groups, and in-depth interviews, she takes up the challenge of expanding the qualitative research frontier.

  2. Methodological lessons in neurophenomenology: Review of a baseline study and recommendations for research approaches.

    Science.gov (United States)

    Bockelman, Patricia; Reinerman-Jones, Lauren; Gallagher, Shaun

    2013-01-01

    Neurophenomenological (NP) methods integrate objective and subjective data in ways that retain the statistical power of established disciplines (like cognitive science) while embracing the value of first-person reports of experience. The present paper positions neurophenomenology as an approach that pulls from traditions of cognitive science but includes techniques that are challenging for cognitive science in some ways. A baseline study is reviewed for "lessons learned," that is, the potential methodological improvements that will support advancements in understanding consciousness and cognition using neurophenomenology. These improvements, we suggest, include (1) addressing issues of interdisciplinarity by purposefully and systematically creating and maintaining shared mental models among research team members; (2) making sure that NP experiments include high standards of experimental design and execution to achieve variable control, reliability, generalizability, and replication of results; and (3) conceiving of phenomenological interview techniques as placing the impetus on the interviewer in interaction with the experimental subject.

  3. Is an increased use of biofuels the road to sustainability?. Consequences of the methodological approach

    Science.gov (United States)

    Johansson, Sheshti; Rydberg, Torbjörn

    2017-02-01

    The global area of planted biofuel crops has been increasing rapidly, but the environmental and social consequences of widespread adoption of biofuel production remain largely unexplored. How do we measure efficiency and net energy of a complex system, such as the interaction between agriculture, human society and technology? This paper provides background and identifies assumptions in its overview of competing and overlapping methods. We emphasize that biofuels, as well as all other resources with their associated processes, should be analyzed as embedded in complex systems. The reason why society looks at biofuels favorably is because the methodological approaches used in the present scientific literature are narrow and far from holistic. What is excluded from the analysis has crucial implications on what is regarded as sustainable.

  4. Worldwide Alien Invasion: A Methodological Approach to Forecast the Potential Spread of a Highly Invasive Pollinator.

    Directory of Open Access Journals (Sweden)

    André L Acosta

    Full Text Available The ecological impacts of alien species invasion are a major threat to global biodiversity. The increasing number of invasion events by alien species and the high cost and difficulty of eradicating invasive species once established require the development of new methods and tools for predicting the most susceptible areas to invasion. Invasive pollinators pose serious threats to biodiversity and human activity due to their close relationship with many plants (including crop species and high potential competitiveness for resources with native pollinators. Although at an early stage of expansion, the bumblebee species Bombus terrestris is becoming a representative case of pollinator invasion at a global scale, particularly given its high velocity of invasive spread and the increasing number of reports of its impacts on native bees and crops in many countries. We present here a methodological framework of habitat suitability modeling that integrates new approaches for detecting habitats that are susceptible to Bombus terrestris invasion at a global scale. Our approach did not include reported invaded locations in the modeling procedure; instead, those locations were used exclusively to evaluate the accuracy of the models in predicting suitability over regions already invaded. Moreover, a new and more intuitive approach was developed to select the models and evaluate different algorithms based on their performance and predictive convergence. Finally, we present a comprehensive global map of susceptibility to Bombus terrestris invasion that highlights priority areas for monitoring.

  5. Quantitative Analysis of Mutant Subclones in Chronic Myeloid Leukemia: Comparison of Different Methodological Approaches.

    Science.gov (United States)

    Preuner, Sandra; Barna, Agnes; Frommlet, Florian; Czurda, Stefan; Konstantin, Byrgazov; Alikian, Mary; Machova Polakova, Katerina; Sacha, Tomasz; Richter, Johan; Lion, Thomas; Gabriel, Christian

    2016-04-29

    Identification and quantitative monitoring of mutant BCR-ABL1 subclones displaying resistance to tyrosine kinase inhibitors (TKIs) have become important tasks in patients with Ph-positive leukemias. Different technologies have been established for patient screening. Various next-generation sequencing (NGS) platforms facilitating sensitive detection and quantitative monitoring of mutations in the ABL1-kinase domain (KD) have been introduced recently, and are expected to become the preferred technology in the future. However, broad clinical implementation of NGS methods has been hampered by the limited accessibility at different centers and the current costs of analysis which may not be regarded as readily affordable for routine diagnostic monitoring. It is therefore of interest to determine whether NGS platforms can be adequately substituted by other methodological approaches. We have tested three different techniques including pyrosequencing, LD (ligation-dependent)-PCR and NGS in a series of peripheral blood specimens from chronic myeloid leukemia (CML) patients carrying single or multiple mutations in the BCR-ABL1 KD. The proliferation kinetics of mutant subclones in serial specimens obtained during the course of TKI-treatment revealed similar profiles via all technical approaches, but individual specimens showed statistically significant differences between NGS and the other methods tested. The observations indicate that different approaches to detection and quantification of mutant subclones may be applicable for the monitoring of clonal kinetics, but careful calibration of each method is required for accurate size assessment of mutant subclones at individual time points.

  6. Worldwide Alien Invasion: A Methodological Approach to Forecast the Potential Spread of a Highly Invasive Pollinator

    Science.gov (United States)

    2016-01-01

    The ecological impacts of alien species invasion are a major threat to global biodiversity. The increasing number of invasion events by alien species and the high cost and difficulty of eradicating invasive species once established require the development of new methods and tools for predicting the most susceptible areas to invasion. Invasive pollinators pose serious threats to biodiversity and human activity due to their close relationship with many plants (including crop species) and high potential competitiveness for resources with native pollinators. Although at an early stage of expansion, the bumblebee species Bombus terrestris is becoming a representative case of pollinator invasion at a global scale, particularly given its high velocity of invasive spread and the increasing number of reports of its impacts on native bees and crops in many countries. We present here a methodological framework of habitat suitability modeling that integrates new approaches for detecting habitats that are susceptible to Bombus terrestris invasion at a global scale. Our approach did not include reported invaded locations in the modeling procedure; instead, those locations were used exclusively to evaluate the accuracy of the models in predicting suitability over regions already invaded. Moreover, a new and more intuitive approach was developed to select the models and evaluate different algorithms based on their performance and predictive convergence. Finally, we present a comprehensive global map of susceptibility to Bombus terrestris invasion that highlights priority areas for monitoring. PMID:26882479

  7. Understanding anorexia: an hermeneutic approach as a methodological alternative for the field of contemporary anorexia research

    Directory of Open Access Journals (Sweden)

    Anne Puuronen

    1999-01-01

    Full Text Available Theories of anorexia nervosa have mainly been dominated by psychiatry and concentrate upon its physiological aspects, both in diagnosis and treatment. This has led to a search for organic causes behind anorectic conditions, instead of seeing it as molded and shaped both by the individual and the socio-cultural context. This "medicalisation" has been an impediment to a more complete conceptualisation of the experience of discipline and of the ascetic modes of action in anorexia. The intension is to approach anorexia as lived process. The focus is not in explaining what cause anorexia, but is centered on the contents of living experience as such. Thus, the author proposes a phenomenological approach to anorexia as a methodological alternative compared to the dominant medico-psychological approaches to anorexia of today. If we consider the body of an anorectic person as an intersection in which the subject's relationship to social reality will be materialized and verified, we are able to see first how accurate a picture of the dual meanings, double bindings and paradoxical commitments of our present culture and its relation to a woman's body anorexia will draw up. Also, because the fact is that anorexia is a predominantly "women's" illness we have to take in account that the construction of subjectivity and in this context the construction of a lived anorectic experience of discipline, is not a gender-neutral process.

  8. Methodologic approach for the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.

    Science.gov (United States)

    Namaste, Sorrel Ml; Aaron, Grant J; Varadhan, Ravi; Peerson, Janet M; Suchdev, Parminder S

    2017-07-01

    Background: The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project is a multiagency and multicountry collaboration that was formed to improve micronutrient assessment and to better characterize anemia.Objectives: The aims of the project were to 1) identify factors associated with inflammation, 2) assess the relations between inflammation, malaria infection, and biomarkers of iron and vitamin A status and compare adjustment approaches, and 3) assess risk factors for anemia in preschool children (PSC) and women of reproductive age (WRA).Design: The BRINDA database inclusion criteria included surveys that 1) were conducted after 2004, 2) had target groups of PSC, WRA, or both, and 3) used a similar laboratory methodology for the measurement of ≥1 biomarker of iron [ferritin or soluble transferrin receptor or vitamin A status (retinol-binding protein or retinol)] and ≥1 biomarker of inflammation (α-1-acid glycoprotein or C-reactive protein). Individual data sets were standardized and merged into a BRINDA database comprising 16 nationally and regionally representative surveys from 14 countries. Collectively, the database covered all 6 WHO geographic regions and contained ∼30,000 PSC and 27,000 WRA. Data were analyzed individually and combined with the use of a meta-analysis.Results: The methods that were used to standardize the BRINDA database and the analytic approaches used to address the project's research questions are presented in this article. Three approaches to adjust micronutrient biomarker concentrations in the presence of inflammation and malaria infection are presented, along with an anemia conceptual framework that guided the BRINDA project's anemia analyses.Conclusions: The BRINDA project refines approaches to interpret iron and vitamin A biomarker values in settings of inflammation and malaria infection and suggests the use of a new regression approach as well as proposes an anemia framework to which real

  9. A methodological approach for landslide economic damage estimation in rural contexts

    Science.gov (United States)

    C, Aucelli, Pietro P.; Balteanu, Dan; Pisano, Luca; Rosskopf, Carmen M.; Zumpano, Veronica

    2014-05-01

    Land degradation due to mass wasting and accelerated water erosion represents at global scale a serious threat to socio-economic development not only in urban areas but also in rural and hence less populated territories where the main economic resources are frequently directly linked to the exploitation of the agricultural, pastoral and natural resources, often threatened especially by landslide phenomena. The assessment of damage induced by landslides, thus, provides an important contribution to support decision making concerning the sustainable management of land use. In this paper a methodological approach developed in GIS environment for valuing the economic damage induced by landslides in rural areas is presented. It allows direct damage estimation related to landslide phenomena by means of a synthetic approach which considers the loss of land value associated with landslides state of activity. This approach was tested in a study area (a small-scale catchment in Molise Region, Southern Italy) which is highly representative of the Adriatic flank of the Molise Apennine, highly exploited for farming and, in the same time, very sensible to slope instability. Several environmental calculation matrices were defined at the pixel scale in relation to different states of activity of landslides. For each cell, soil uses and related Average Agricultural Values (AAVs) were determined. The economic damage value (DV) was computed by multiplying the obtained specified AAV with a specific landslide-damage index (LDI) which was calculated on the basis of the extent and state of activity of landslides within each cell. This procedure allowed the estimation of the DV and the real agricultural value for each cell. Summing up the results coming from each cell, the total loss of land value due to landslides and the residual total agricultural value for the entire study area were calculated. Furthermore, in order to assess for the entire study area the landslide exposition of rural

  10. Approaches and Methodologies for a Course on History and Epistemology of Physics: Analyzing the Experience of a Brazilian University

    Science.gov (United States)

    Rosa, Katemari; Martins, Maria Cristina

    2009-01-01

    This paper is an analysis of inserting history and philosophy of science (HPS) in a physics undergraduate program at a Brazilian university. It is an examination of the approaches and methodologies adopted by professors of a History and Epistemology course. The course aims to have an explicit approach to HPS. The results suggest a concern of the…

  11. Methodological approach for an integrated environmental monitoring system relative to heavy metals from an incineration plant

    Energy Technology Data Exchange (ETDEWEB)

    Morselli, L.; Passarini, F.; Zamagni, E.; Brusori, B. [Bologna Univ., Bologna (Italy). Dipt. di Chimica Industriale e dei Materiali, Facolta' di Chimica Industriale

    2000-12-01

    The use of an integrated environmental monitoring system is an innovative and very important approach for the determination of environmental impacts due to a contamination source. In the present work, the methodological approach is described and applied to the case study of a MSW incineration plant. Heavy metals were chosen as Environmental Indicators. Gaseous emissions were measured and correlated to wet and dry depositions, soil and vegetation samples. Results show a good correlation between stack emissions and atmospheric deposition; less with soil and vegetation, but these results are important in order to design a standard procedure for an Integrated Monitoring System. [Italian] L'uso di un Sistema Integrato di Monitoraggio Ambientale rappresenta un approccio innovativo ed estremamente importante per la determinazione degli impatti ambientali derivanti da una fonte di contaminazione. Nel presente lavoro questo approccio metodologico viene descritto e applicato al caso studio di un impianto di incenerimento di Rifiuti Solidi Urbani. I metalli pesanti sono stati scelti come Indicatori Ambientali. Le emissioni gassose dal camino sono state misurate e correlate con le deposizioni secche ed umide e con alcuni campioni di suolo e di vegetazione. I risultati mettono in rilievo una buona correlazione tra emissioni al camino e deposizioni atmosferiche; meno con suolo e vegetali, ma i risultati rimangono importanti ai fini della definizione di una procedura generale di riferimento per un Sistema Integrato di Monitoraggio.

  12. Preventing landslides on terraced slopes: A methodological approach in planning and constructing new terraces

    Science.gov (United States)

    Ažman Momirski, Lucija

    2015-04-01

    In everyday practice, the construction of terraces does not follow a premade plan. Consequently, poorly designed and maintained terraces are often significant sediment sources induced by terrace collapse. The purpose of a plan for terrace construction is to arrange terraces according to geological, geomechanical, geodetic, agricultural, and other data. It is possible to anticipate the consequences of these arrangements through carefully considered decisions (about the ratio of the terrace slope, the quantity and direction of soil shifted when constructing terraces, fitting the terrace geometry to the terrain geometry, the width and length of terrace plains, the inclinations of terrace plains, the construction of field roads and turning points, the construction of drainage for removing groundwater, and other factors). Such a methodological approach in planning and constructing new terraces ensures greater stability of terraces, the smallest quantity of earth shifted, and the greatest possible area of usable land. Building terraces is a direct method for preventing landslides. Building terraces according to a plan increases the efficiency of this method. Such an approach is even more important in areas where terraces extend from the top to bottom of slopes. Two case studies from the Mediterranean area are presented: old terraces from Brkini area, where terraces and their slopes have preserved the same form for almost two hundred years, and the planning process for newly constructed terraced vineyards in the Gorizia Hills with post-project monitoring.

  13. An Alternative Methodological Approach for Cost-Effectiveness Analysis and Decision Making in Genomic Medicine.

    Science.gov (United States)

    Fragoulakis, Vasilios; Mitropoulou, Christina; van Schaik, Ron H; Maniadakis, Nikolaos; Patrinos, George P

    2016-05-01

    Genomic Medicine aims to improve therapeutic interventions and diagnostics, the quality of life of patients, but also to rationalize healthcare costs. To reach this goal, careful assessment and identification of evidence gaps for public health genomics priorities are required so that a more efficient healthcare environment is created. Here, we propose a public health genomics-driven approach to adjust the classical healthcare decision making process with an alternative methodological approach of cost-effectiveness analysis, which is particularly helpful for genomic medicine interventions. By combining classical cost-effectiveness analysis with budget constraints, social preferences, and patient ethics, we demonstrate the application of this model, the Genome Economics Model (GEM), based on a previously reported genome-guided intervention from a developing country environment. The model and the attendant rationale provide a practical guide by which all major healthcare stakeholders could ensure the sustainability of funding for genome-guided interventions, their adoption and coverage by health insurance funds, and prioritization of Genomic Medicine research, development, and innovation, given the restriction of budgets, particularly in developing countries and low-income healthcare settings in developed countries. The implications of the GEM for the policy makers interested in Genomic Medicine and new health technology and innovation assessment are also discussed.

  14. Plant biodiversity of beech forests in central-northern Italy: a methodological approach for conservation purposes

    Directory of Open Access Journals (Sweden)

    Marcantonio M

    2012-07-01

    Full Text Available Forests are reckoned essentials as biodiversity reservoirs and carbon sinks. Current threats to forest ecosystems (e.g., climate changes, habitat loss and fragmentation, management changes call for monitoring their biodiversity and preserving their ecological functions. In this study, we characterized plants diversity of five beech forests located in central and north Apennines mountain chain, using results by a probabilistic sampling. In order to achieve our goals, we have considered species richness and abundance, taxonomic distinctness and species composition, using both old and new analytical approaches. Results have shown how: (1 the forest type dominated by Fagus sylvatica is characterized by high complexity, with marked compositional, structural and biodiversity differences; (2 beech forests of Pigelleto di Piancastagnaio and Valle della Corte show the highest plants diversity values. The ecological characteristics of these areas, which sustain high diversity values, are unique and of great conservation interest; (3 the use of species richness as the only diversity measure have not allowed an efficient differentiation between studied areas. Indeed, the use of different indexes and analytical methods is required to detect multiple characteristics of biological diversity, as well as to carry out efficient biodiversity surveys aimed to develop optimal conservation strategies. In the future, we plan to apply the sampling methodology and the analytical approach used in this paper to characterize plants diversity of similar forest types.

  15. Methodological approaches to evaluate teratogenic risk using birth defect registries: advantages and disadvantages.

    Directory of Open Access Journals (Sweden)

    Fernando A Poletta

    Full Text Available BACKGROUND: Different approaches have been used in case-control studies to estimate maternal exposure to medications and the risk of birth defects. However, the performance of these approaches and how they affect the odds ratio (OR estimates have not been evaluated using birth-defect surveillance programmes. The aim of this study was to evaluate the scope and limitations of three case-control approaches to assess the teratogenic risk of birth defects in mothers exposed to antiepileptic medications, insulin, or acetaminophen. METHODOLOGY/PRINCIPAL FINDINGS: We studied 110,814 non-malformed newborns and 58,514 live newborns with birth defects registered by the Latin American Collaborative Study of Congenital Anomalies (ECLAMC between 1967 and 2008. Four controls were randomly selected for each case in the same hospital and period, and three different control groups were used: non-malformed newborns (HEALTHY, malformed newborns (SICK, and a subgroup of SICK, only-exposed cases (OECA. Associations were evaluated using OR and Pearson's chi-square (P<0.01. There were no concordance correlations between the HEALTHY and OECA designs, and the average OR differences ranged from 3.0 to 11.5 for the three evaluated medicines. The overestimations observed for HEALTHY design were increased as higher OR values were given, with a high and statistically significant correlation between the difference and the mean. On the contrary, the concordance correlations obtained between the SICK and OECA designs were quite good, with no significant differences in the average risks. CONCLUSIONS: The HEALTHY design estimates the true population OR, but shows a high rate of false-positive results presumably caused by differential misclassification bias. This bias decreases with the increase of the proportion of exposed controls. SICK and OECA odds ratios cannot be considered a direct estimate of the true population OR except under certain conditions. However, the SICK and OECA

  16. Methodological Approaches to Evaluate Teratogenic Risk Using Birth Defect Registries: Advantages and Disadvantages

    Science.gov (United States)

    Poletta, Fernando A.; López Camelo, Jorge S.; Gili, Juan A.; Leoncini, Emmanuele; Castilla, Eduardo E.; Mastroiacovo, Pierpaolo

    2012-01-01

    Background Different approaches have been used in case-control studies to estimate maternal exposure to medications and the risk of birth defects. However, the performance of these approaches and how they affect the odds ratio (OR) estimates have not been evaluated using birth-defect surveillance programmes. The aim of this study was to evaluate the scope and limitations of three case-control approaches to assess the teratogenic risk of birth defects in mothers exposed to antiepileptic medications, insulin, or acetaminophen. Methodology/Principal Findings We studied 110,814 non-malformed newborns and 58,514 live newborns with birth defects registered by the Latin American Collaborative Study of Congenital Anomalies (ECLAMC) between 1967 and 2008. Four controls were randomly selected for each case in the same hospital and period, and three different control groups were used: non-malformed newborns (HEALTHY), malformed newborns (SICK), and a subgroup of SICK, only-exposed cases (OECA). Associations were evaluated using OR and Pearson's chi-square (P<0.01). There were no concordance correlations between the HEALTHY and OECA designs, and the average OR differences ranged from 3.0 to 11.5 for the three evaluated medicines. The overestimations observed for HEALTHY design were increased as higher OR values were given, with a high and statistically significant correlation between the difference and the mean. On the contrary, the concordance correlations obtained between the SICK and OECA designs were quite good, with no significant differences in the average risks. Conclusions The HEALTHY design estimates the true population OR, but shows a high rate of false-positive results presumably caused by differential misclassification bias. This bias decreases with the increase of the proportion of exposed controls. SICK and OECA odds ratios cannot be considered a direct estimate of the true population OR except under certain conditions. However, the SICK and OECA designs could

  17. Scenario development as a basis for formulating a research program on future agriculture: a methodological approach.

    Science.gov (United States)

    Oborn, Ingrid; Bengtsson, Jan; Hedenus, Fredrik; Rydhmer, Lotta; Stenström, Maria; Vrede, Katarina; Westin, Charles; Magnusson, Ulf

    2013-11-01

    To increase the awareness of society to the challenges of global food security, we developed five contrasting global and European scenarios for 2050 and used these to identify important issues for future agricultural research. Using a scenario development method known as morphological analysis, scenarios were constructed that took economic, political, technical, and environmental factors into account. With the scenarios as a starting point future challenges were discussed and research issues and questions were identified in an interactive process with stakeholders and researchers. Based on the outcome of this process, six socioeconomic and biophysical overarching challenges for future agricultural were formulated and related research issues identified. The outcome was compared with research priorities generated in five other research programs. In comparison, our research questions focus more on societal values and the role of consumers in influencing agricultural production, as well as on policy formulation and resolving conflicting goals, areas that are presently under-represented in agricultural research. The partly new and more interdisciplinary research priorities identified in Future Agriculture compared to other programs analyzed are likely a result of the methodological approach used, combining scenarios and interaction between stakeholders and researchers.

  18. Enabling Mobile Communications for the Needy: Affordability Methodology, and Approaches to Requalify Universal Service Measures

    Directory of Open Access Journals (Sweden)

    Louis-Francois PAU

    2009-01-01

    Full Text Available This paper links communications and media usage to social and household economics boundaries. It highlights that in present day society, communications and media are a necessity, but not always affordable, and that they furthermore open up for addictive behaviors which raise additional financial and social risks. A simple and efficient methodology compatible with state-of-the-art social and communications business statistics is developed, which produces the residual communications and media affordability budget and ultimately the value-at-risk in terms of usage and tariffs. Sensitivity analysis provides precious information on bottom-up communications and media adoption on the basis of affordability. This approach differs from the regulated but often ineffective Universal service obligation, which instead of catering for individual needs mostly addresses macro-measures helping geographical access coverage (e.g. in rural areas. It is proposed to requalify the Universal service obligations on operators into concrete measures, allowing, with unchanged funding, the needy to adopt mobile services based on their affordability constraints by bridging the gap to a standard tariff. Case data are surveyed from various countries. ICT policy recommendations are made to support widespread and socially responsible communications access.

  19. The game as strategy for approach to sexuality with adolescents: theoretical-methodological reflections

    Directory of Open Access Journals (Sweden)

    Vânia de Souza

    Full Text Available ABSTRACT Objective: To describe the Papo Reto [Straight Talk] game and reflect on its theoretical-methodological basis. Method: Analytical study on the process of elaboration of the Papo Reto online game, destined to adolescents aged 15-18 years, with access to the Game between 2014 and 2015. Results: the interactions of 60 adolescents from Belo Horizonte and São Paulo constituted examples of the potentialities of the Game to favor the approach to sexuality with adolescents through simulation of reality, invention and interaction. Based on those potentialities, four thinking categories were discussed: the game as pedagogic device; the game as simulation of realities; the game as device for inventive learning; and the game empowering the interaction. Conclusion: By permitting that the adolescents take risks on new ways, the Game allows them to become creative and active in the production of senses, in the creation of their discourses and in the ways of thinking, feeling and acting in the sexuality field.

  20. Conceptual and methodological approaches to evaluation of investment attractiveness of enterprises engaged in transportations

    Directory of Open Access Journals (Sweden)

    Olha Myshkovych

    2016-12-01

    Full Text Available The aim of the article is to analyze the conceptual and methodological approaches to determining the investment attractiveness of enterprises engaged in transportations. It is indicated that the investment attractiveness of transport enterprises should be determined by calculating of the overall financial situation of enterprises, which will allow potential investors to evaluate profitability and cost efficiency of its activity. An analysis of the strengths and weaknesses of the enterprise engaged in transportation can be accomplished by the evaluation of its innovative capacity. The identification of factors and reserves of the increasing of enterprise innovative development will allow distinguishing of the basic directions for the improvement of organizational and economic mechanism of its activity. With the aim of building the strategy for the strengthening of market position it is also considered important for the potential investor to obtain the information about enterprise place on the national and international markets. Political and legal environment, characterized by political stability of society and the regulatory framework of entrepreneurial and investment activity serve as a certain guarantee of the investment reliability.

  1. A simplified approach for monitoring hydrophobic organic contaminants associated with suspended sediment: Methodology and applications

    Science.gov (United States)

    Mahler, B.J.; Van Metre, P.C.

    2003-01-01

    Hydrophobic organic contaminants, although frequently detected in bed sediment and in aquatic biota, are rarely detected in whole-water samples, complicating determination of their occurrence, load, and source. A better approach for the investigation of hydrophobic organic contaminants is the direct analysis of sediment in suspension, but procedures for doing so are expensive and cumbersome. We describe a simple, inexpensive methodology for the dewatering of sediment and present the results of two case studies. Isolation of a sufficient mass of sediment for analyses of organochlorine compounds and PAHs is obtained by in-line filtration of large volumes of water. The sediment is removed from the filters and analyzed directly by standard laboratory methods. In the first case study, suspended-sediment sampling was used to determine occurrence, loads, and yields of contaminants in urban runoff affecting biota in Town Lake, Austin, TX. The second case study used suspended-sediment sampling to locate a point source of PCBs in the Donna Canal in south Texas, where fish are contaminated with PCBs. The case studies demonstrate that suspended-sediment sampling can be an effective tool for determining the occurrence, load, and source of hydrophobic organic contaminants in transport.

  2. Methodological Approach and Basic Analysis of Maritime Labour Market Needs by Case of Estonia

    Directory of Open Access Journals (Sweden)

    Anatoli Alop

    2016-12-01

    Full Text Available The Estonian Government has adopted Estonian Marine Policy 2012–2020 (EMP as a long-term planning basis for the development of maritime sector in Estonia. A number of practical tasks shall provide the achieving of goals posed by development plan. One of goals is working out the strategy for development of maritime education and training (MET in Estonia at least for next 10 years. An enquiry among the enterprises and other actors closely re-lated to maritime sector has been conducted as first stage of this job. The main goal of it was to define the Estonian labour market needs and to adumbrate the vision for trends and developments in field until 2025. The working out of above-mentioned strategy will be completed by Estonian Maritime Academy of TUT by the end of 2016. The results of first stage were received by the end of 2015; authors of this paper describe and explain the methodological approach using for such study work as well as the instruments used and make the short analysis of results paying special attention to problems and “bottle necks” arising in course of such enquiry.

  3. A simplified approach for monitoring hydrophobic organic contaminants associated with suspended sediment: methodology and applications.

    Science.gov (United States)

    Mahler, B J; Van Metre, P C

    2003-04-01

    Hydrophobic organic contaminants, although frequently detected in bed sediment and in aquatic biota, are rarely detected in whole-water samples, complicating determination of their occurrence, load, and source. A better approach for the investigation of hydrophobic organic contaminants is the direct analysis of sediment in suspension, but procedures for doing so are expensive and cumbersome. We describe a simple, inexpensive methodology for the dewatering of sediment and present the results of two case studies. Isolation of a sufficient mass of sediment for analyses of organochlorine compounds and PAHs is obtained by in-line filtration of large volumes of water. The sediment is removed from the filters and analyzed directly by standard laboratory methods. In the first case study, suspended-sediment sampling was used to determine occurrence, loads, and yields of contaminants in urban runoff affecting biota in Town Lake, Austin, TX. The second case study used suspended-sediment sampling to locate a point source of PCBs in the Donna Canal in south Texas, where fish are contaminated with PCBs. The case studies demonstrate that suspended-sediment sampling can be an effective tool for determining the occurrence, load, and source of hydrophobic organic contaminants in transport.

  4. METHODOLOGICAL APPROACH TO THE PHENOMENON OF SOCIAL RESPONSIBILITY OF THE INDIVIDUAL

    Directory of Open Access Journals (Sweden)

    L. A. Saenko

    2016-01-01

    Full Text Available The authors present an analysis of the phenomenon of "social responsibility of the individual" research from various perspectives. Based on the research of domestic and foreign scientists, as well as the experience of the authors own activities build mechanisms of socially responsible behavior of the person. Emphasis is based on the research of R. Selman, a conductive connection between social responsibility and social intelligence of the individual. In the article are described results of F. Haider’s research, linking the level of social responsibility to the level of individual development. The authors present a study of the specificity of social responsibility through the prism of methodological approaches: a systematic structural, systemic, the activity, axiological, subjective. Presented the scheme, which reflects the social responsibility as part of the social structure. It was concluded that social responsibility is an element of the social structure of the personality and integrates the social and psychological components. On the social responsibility of the structure affect state social policy, civil society and social micro-groups. The authors note that it is necessary not only to develop the social responsibility of the individual, but also to stimulate the formation of socially responsible area.

  5. A new approach to synthesis of benzyl cinnamate: Optimization by response surface methodology.

    Science.gov (United States)

    Zhang, Dong-Hao; Zhang, Jiang-Yan; Che, Wen-Cai; Wang, Yun

    2016-09-01

    In this work, the new approach to synthesis of benzyl cinnamate by enzymatic esterification of cinnamic acid with benzyl alcohol is optimized by response surface methodology. The effects of various reaction conditions, including temperature, enzyme loading, substrate molar ratio of benzyl alcohol to cinnamic acid, and reaction time, are investigated. A 5-level-4-factor central composite design is employed to search for the optimal yield of benzyl cinnamate. A quadratic polynomial regression model is used to analyze the experimental data at a 95% confidence level (P<0.05). The coefficient of determination of this model is found to be 0.9851. Three sets of optimum reaction conditions are established, and the verified experimental trials are performed for validating the optimum points. Under the optimum conditions (40°C, 31mg/mL enzyme loading, 2.6:1 molar ratio, 27h), the yield reaches 97.7%, which provides an efficient processes for industrial production of benzyl cinnamate.

  6. A structured approach to transforming a large public hospital emergency department via lean methodologies.

    Science.gov (United States)

    Naik, Trushar; Duroseau, Yves; Zehtabchi, Shahriar; Rinnert, Stephan; Payne, Rosamond; McKenzie, Michele; Legome, Eric

    2012-01-01

    Emergency Departments (EDs) face significant challenges in providing efficient, quality, safe, cost-effective care. Lean methodologies are a proposed framework to redesign ED practices and processes to meet these challenges. We outline a systematic way that lean principles can be applied across the entire ED patient experience to transform a high volume ED in a safety net hospital. We review the change in ED performance metrics prior to and after lean implementation. We discuss critical insights and key lessons learned from our lean transformation to date. The steps to implementing lean principles across the patient's ED experience are described with specific attention to executive planning of rapid improvement experiments and the subsequent roll-out of lean transformation over an 18-month time frame. Basic ED performance data were compared to the year prior. Results of the exploratory analysis (using median and interquartile ranges and nonparametric tests for group comparisons) have shown improvement in several performance metrics after initiating lean transformation. The approach, lessons learned, and early data of our transformation can provide critical insights for EDs seeking to incorporate continuous improvement strategies. Key lessons and unique challenges encountered in safety net hospitals are discussed.

  7. Clinical trials in Huntington's disease: Interventions in early clinical development and newer methodological approaches.

    Science.gov (United States)

    Sampaio, Cristina; Borowsky, Beth; Reilmann, Ralf

    2014-09-15

    Since the identification of the Huntington's disease (HD) gene, knowledge has accumulated about mechanisms directly or indirectly affected by the mutated Huntingtin protein. Transgenic and knock-in animal models of HD facilitate the preclinical evaluation of these targets. Several treatment approaches with varying, but growing, preclinical evidence have been translated into clinical trials. We review major landmarks in clinical development and report on the main clinical trials that are ongoing or have been recently completed. We also review clinical trial settings and designs that influence drug-development decisions, particularly given that HD is an orphan disease. In addition, we provide a critical analysis of the evolution of the methodology of HD clinical trials to identify trends toward new processes and endpoints. Biomarker studies, such as TRACK-HD and PREDICT-HD, have generated evidence for the potential usefulness of novel outcome measures for HD clinical trials, such as volumetric imaging, quantitative motor (Q-Motor) measures, and novel cognitive endpoints. All of these endpoints are currently applied in ongoing clinical trials, which will provide insight into their reliability, sensitivity, and validity, and their use may expedite proof-of-concept studies. We also outline the specific opportunities that could provide a framework for a successful avenue toward identifying and efficiently testing and translating novel mechanisms of action in the HD field.

  8. What People Tweet: A Methodological Approach to Exploring Language Functions in Content from Twitter

    Directory of Open Access Journals (Sweden)

    Mabel Valeria González Cogliano

    2015-01-01

    Full Text Available This paper presents a methodological approach to explore the functions of the contents published by Twitter users, using as a theoretical foundation the model of Jakobson. Once the analytical tool was designed, it was validated with a case study. As an example of its applicability, the content published by the most active users in the following and follower section of a personal Twitter account were analyzed. Eleven thousand two hundred tweets were analyzed. From that analysis, some treats are proposed that could serve later to generate profiles. These profiles could illustrate, in what way Twitter users publish their content to inform, to brag, to judge or simply to play with language. The results explore the possibility of by means of function analysis and construction of users profiles, it might be plausible to reflect on the nature of 2.0 communication and its effcts on our interactions with one another.

  9. A methodological approach to investigating a nationwide clinical specimen contamination problem in England.

    Science.gov (United States)

    Pezzoli, L; Campbell, C; Lamagni, T L; Johnson, E; Saei, A; Duckworth, G

    2009-06-11

    Outbreaks of pseudo-infection due to contamination of specimens have been described, often as localised incidents. From August 2006, several English hospital laboratories began to refer an unusually high number of isolates of the fungus Paecilomyces variotii from clinical specimens to the national mycology reference laboratory for microbiological testing. We describe the methods used during the outbreak investigation in order to provide infection control specialists with an overview of how such national incidents may be investigated. We surveyed the hospitals reporting the contamination problem and conducted microbiological and environmental sampling. We applied analytical epidemiology to supply chain data, comparing the supply lines of key equipment to affected and unaffected hospitals in England. The survey was useful to describe procedures and equipment in use in the hospitals reporting the problem. The microbiological aspects of the investigation helped us understand how the fungal spores were distributed in the hospital environment. In the supply chain investigation we used data that was previously only used for logistical purposes. Overall the investigation was methodologically challenging, with no existing protocol to guide the investigators. To our knowledge, this is a novel approach to the investigation of such a widespread contamination problem, affecting geographically disparate hospitals at the same time.

  10. Application of Direct Assessment Approaches and Methodologies to Cathodically Protected Nuclear Waste Transfer Lines

    Energy Technology Data Exchange (ETDEWEB)

    Dahl, Megan M. [ARES Corporation, Richland, WA (United States); Pikas, Joseph [Schiff Associates, Sugar Land TX (United States); Edgemon, Glenn L. [ARES Corporation, Richland, WA (United States); Philo, Sarah [ARES Corporation, Richland, WA (United States)

    2013-01-22

    The U.S. Department of Energy's (DOE) Hanford Site is responsible for the safe storage, retrieval, treatment, and disposal of approximately 54 million gallons (204 million liters) of radioactive waste generated since the site's inception in 1943. Today, the major structures involved in waste management at Hanford include 149 carbon steel single-shell tanks, 28 carbon-steel double-shell tanks, plus a network of buried metallic transfer lines and ancillary systems (pits, vaults, catch tanks, etc.) required to store, retrieve, and transfer waste within the tank farm system. Many of the waste management systems at Hanford are still in use today. In response to uncertainties regarding the structural integrity of these systems,' an independent, comprehensive integrity assessment of the Hanford Site piping system was performed. It was found that regulators do not require the cathodically protected pipelines located within the Hanford Site to be assessed by External Corrosion Direct Assessment (ECDA) or any other method used to ensure integrity. However, a case study is presented discussing the application of the direct assessment process on pipelines in such a nuclear environment. Assessment methodology and assessment results are contained herein. An approach is described for the monitoring, integration of outside data, and analysis of this information in order to identify whether coating deterioration accompanied by external corrosion is a threat for these waste transfer lines.

  11. Knowing How Good Our Searches Are: An Approach Derived from Search Filter Development Methodology

    Directory of Open Access Journals (Sweden)

    Sarah Hayman

    2015-12-01

    Full Text Available Objective – Effective literature searching is of paramount importance in supporting evidence based practice, research, and policy. Missed references can have adverse effects on outcomes. This paper reports on the development and evaluation of an online learning resource, designed for librarians and other interested searchers, presenting an evidence based approach to enhancing and testing literature searches. Methods – We developed and evaluated the set of free online learning modules for librarians called Smart Searching, suggesting the use of techniques derived from search filter development undertaken by the CareSearch Palliative Care Knowledge Network and its associated project Flinders Filters. The searching module content has been informed by the processes and principles used in search filter development. The self-paced modules are intended to help librarians and other interested searchers test the effectiveness of their literature searches, provide evidence of search performance that can be used to improve searches, as well as to evaluate and promote searching expertise. Each module covers one of four techniques, or core principles, employed in search filter development: (1 collaboration with subject experts; (2 use of a reference sample set; (3 term identification through frequency analysis; and (4 iterative testing. Evaluation of the resource comprised ongoing monitoring of web analytics to determine factors such as numbers of users and geographic origin; a user survey conducted online elicited qualitative information about the usefulness of the resource. Results – The resource was launched in May 2014. Web analytics show over 6,000 unique users from 101 countries (at 9 August 2015. Responses to the survey (n=50 indicated that 80% would recommend the resource to a colleague. Conclusions – An evidence based approach to searching, derived from search filter development methodology, has been shown to have value as an online learning

  12. A new methodological approach for PET implementation in radiotherapy treatment planning.

    Science.gov (United States)

    Bellan, Elena; Ferretti, Alice; Capirci, Carlo; Grassetto, Gaia; Gava, Marcello; Chondrogiannis, Sotirios; Virdis, Graziella; Marzola, Maria Cristina; Massaro, Arianna; Rubello, Domenico; Nibale, Otello

    2012-05-01

    In this paper, a new methodological approach to using PET information in radiotherapy treatment planning has been discussed. Computed tomography (CT) represents the primary modality to plan personalized radiation treatment, because it provides the basic electron density map for correct dose calculation. If PET scanning is also performed it is typically coregistered with the CT study. This operation can be executed automatically by a hybrid PET/CT scanner or, if the PET and CT imaging sets have been acquired through different equipment, by a dedicated module of the radiotherapy treatment planning system. Both approaches have some disadvantages: in the first case, the bore of a PET/CT system generally used in clinical practice often does not allow the use of certain bulky devices for patient immobilization in radiotherapy, whereas in the second case the result could be affected by limitations in window/level visualization of two different image modalities, and the displayed PET volumes can appear not to be related to the actual uptake into the patient. To overcome these problems, at our centre a specific procedure has been studied and tested in 30 patients, allowing good results of precision in the target contouring to be obtained. The process consists of segmentation of the biological target volume by a dedicated PET/CT console and its export to a dedicated radiotherapy system, where an image registration between the CT images acquired by the PET/CT scanner and a large-bore CT is performed. The planning target volume is contoured only on the large-bore CT and is used for virtual simulation, to individuate permanent skin markers on the patient.

  13. Low-income DSM Programs: Methodological approach to determining the cost-effectiveness of coordinated partnerships

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A.; Hill, L.J.

    1994-05-01

    As governments at all levels become increasingly budget-conscious, expenditures on low-income, demand-side management (DSM) programs are being evaluated more on the basis of efficiency at the expense of equity considerations. Budgetary pressures have also caused government agencies to emphasize resource leveraging and coordination with electric and gas utilities as a means of sharing the expenses of low-income programs. The increased involvement of electric and gas utilities in coordinated low-income DSM programs, in turn, has resulted in greater emphasis on estimating program cost-effectiveness. The objective of this study is to develop a methodological approach to estimate the cost- effectiveness of coordinated low-income DSM programs, given the special features that distinguish these programs from other utility-operated DSM programs. The general approach used in this study was to (1) select six coordinated low-income DSM programs from among those currently operating across the United States, (2) examine the main features of these programs, and (3) determine the conceptual and pragmatic problems associated with estimating their cost-effectiveness. Three types of coordination between government and utility cosponsors were identified. At one extreme, local agencies operate {open_quotes}parallel{close_quotes} programs, each of which is fully funded by a single sponsor (e.g., one funded by the U.S. Department of Energy and the other by a utility). At the other extreme are highly {open_quotes}coupled{close_quotes} programs that capitalize on the unique capabilities and resources offered by each cosponsor. In these programs, agencies employ a combination of utility and government funds to deliver weatherization services as part of an integrated effort. In between are {open_quotes}supplemental{close_quotes} programs that utilize resources to supplement the agency`s government-funded weatherization, with no changes to the operation of that program.

  14. Connecting the East and the West, the Local and the Universal: The Methodological Elements of a Transcultural Approach to Bioethics.

    Science.gov (United States)

    Nie, Jing-Bao; Fitzgerald, Ruth P

    From the outset, cross-cultural and transglobal bioethics has constituted a potent arena for a dynamic public discourse and academic debate alike. But prominent bioethical debates on such issues as the notion of common morality and a distinctive "Asian" bioethics in contrast to a "Western" one reveal some deeply rooted and still popular but seriously problematic methodological habits in approaching cultural differences, most notably, radically dichotomizing the East and the West, the local and the universal. In this paper, a "transcultural" approach to bioethics and cultural studies is proposed. It takes seriously the challenges offered by social sciences, anthropology in particular, towards the development of new methodologies for comparative and global bioethics. The key methodological elements of "transculturalism" include acknowledging the great internal plurality within every culture; highlighting the complexity of cultural differences; upholding the primacy of morality; incorporating a reflexive theory of social power; and promoting changes or progress towards shared and sometimes new moral values.

  15. [The scientific discourse about dementia in Germany-first results of the exemplary exercise of an integrative methodological approach].

    Science.gov (United States)

    Panke-Kochinke, Birgit; Krause, Gabriele; Klimann, Olga

    2015-08-01

    The analysis of the discourse in dealing with people with dementia within the nursing and healthcare research in Germany is previously missing.Aim: How are people with dementia described in the discourse of the German nursing and health care research community and what does that mean for the nursing and health research in Germany? Using an integrative methodological approach, the first steps of an analysis of dementia discourse are developed and exemplarily tested in a selected limited context datjramework. The scientific discourse is focused on the burden or the family aregivers of the person with dementia.They are identified as those who have to handle the burden with their spouse or siblings with dementia. A methodologiCal approach of integrative analysis was tested. According perspectives should be developed to incorporate the perspective of people with dementia in a stronger way.

  16. A simplified methodology to approach the complexity of foraminiferal calcite oxygen-isotope data - model comparison

    Science.gov (United States)

    Roche, Didier; Waelbroeck, Claire

    2016-04-01

    Since the pioneering work of Epstein (Epstein et al., 1953), numerous calcite isotopic records from the ocean have been used to attempt reconstructing paleoclimatic information. Additional to the well known complexity brought by the fact that foraminiferal calcite records both temperature and isotopic composition of the surrounding oceanic waters, an additional effect for surface - dwelling foraminifers is the fact that two different species do not have the same habitat and may thus record different signals. This is obvious when comparing paleoclimatic records where different species have been measured for the isotopic composition of the calcite. The difference in habitat produces a three dimensional spatial complexity (a foraminifera living in preferred climatic conditions at a specific location, but also at a specific depth, sometimes far from the surface) but also a temporal uncertainty (foraminifers generally live for only a few weeks and their growth season may be evolving through time with climate change). While the different species habitats potentially contain a wealth of information that could be used to better understand the sequences of climate change, this has seldom been used in modeling studies, most models deriving calcite isotopic signal from surface and annual mean conditions (e.g. Roche et al., 2014). In the present work, we propose a reduced complexity approach to compute the calcite for several planktonic foraminifers from climate model simulations under pre-industrial conditions. We base our approach on simple functions describing the temperature dependence of the different species growth rates (Lombard et al., 2009) and on probability of presence based on the physical variables computed in the climate model. We present a comparison to available sediment traps and core tops data as a validation of the methodology, focusing on the possibility for future applicability towards inversion of the signal measured in oceanic sediment cores. References

  17. The Contemporary Transdisciplinary Approach as a Methodology to Aid Students of Humanities and Social Sciences

    Science.gov (United States)

    Todorova, Petia

    2013-01-01

    In this paper, the author (Todorova, Petia) addresses the problems students of humanities and social sciences face in the choice of methodology which they should employ in the theoretic discussion of a given task. This is due to the fact that in the course of their education the necessity of methodological competency is largely neglected and is…

  18. A Methodological Demonstration of Set-theoretical Approach to Social Media Maturity Models Using Necessary Condition Analysis

    DEFF Research Database (Denmark)

    Lasrado, Lester Allan; Vatrapu, Ravi; Andersen, Kim Normann

    2016-01-01

    Despite being widely accepted and applied across research domains, maturity models have been criticized for lacking academic rigor, especially methodologically rigorous and empirically grounded or tested maturity models are quite rare. Attempting to close this gap, we adopt a set-theoretic approach...

  19. Tagung: "Beyond the Master’s Tools: Post- and Decolonial Approaches to Research Methodology and Methods in the Social Sciences"

    OpenAIRE

    Lesch, Max

    2015-01-01

    Vom 14. bis 15. Januar 2016 findet in Kassel eine Konferenz zum Thema "Beyond the Master's Tools: Post- and Decolonial Approaches to Research Methodology and Methods in the Social Sciences" statt. Veranstaltet wird die Konferenz von den Fachbereichen Postkoloniale Studien und Soziologie der Diversität der Universität Kassel.

  20. Examining Change in Metacognitive Knowledge and Metacognitive Control During Motor Learning: What Can be Learned by Combining Methodological Approaches?

    OpenAIRE

    Claire Sangster Jokić; David Whitebread

    2014-01-01

    Growing recognition of the importance of understanding metacognitive behaviour as it occurs in everyday learning situations has prompted an expansion of the methodological approaches used to examine metacognition. This becomes especially pertinent when examining the process of metacognitive change, where 'on-line' observational approaches able to capture metacognitive performance as it occurs during socially-mediated learning are being increasingly applied. This study applied a mixed methods ...

  1. Current methodological approaches to determining the environmental competitiveness of products and manufacturers

    Directory of Open Access Journals (Sweden)

    S.K. Harichkov

    2013-09-01

    Full Text Available The aim of the article. The aim of the article is to develop methodological approaches to environmental assessments and enterprise competitiveness.The results of the analysis. Ensuring environmental competitiveness of producers and their products should be based on the creation of conditions for access to restricted environmentally friendly natural resources as factors of production. Environmentally friendly products may not be carried out under conditions of companies that pollute the environment. Environmental competitiveness of producers is provided based on two of its constituent factors. First it's impact on the environment: the value of economic - environmental damage inflicted terms of air emissions, discharges into water, waste disposal in water and land facilities, depletion of all natural resources in the process of extraction and application economic-environmental damage to the environment in the extraction of natural resources. The second factor is the production of environmentally viable products. Environmental competitiveness of goods is determined by environmental parameters as a commodity and its price are acceptable to consumers and appropriate to the effective demand for certain markets in certain time periods. An important condition for the formation of the competitive nature of the process is the qualitative state factors of production, which, in turn, depends on the environmental component condition, performance, environment, sustainability of natural resource base of the national economy.To environmental performance include:level (content contaminants in combustion engines of vehicles, equipment, machinery, facilities,the probability of harmful particles, gases emissions during storage, transportation, use or consumption of goods;radioactivity of the final product and others.Methods of assessing the environmental performance of the enterprise should consist of the following steps:Gathering and analyzing baseline information

  2. Systemic Inflammation: Methodological Approaches to Identification of the Common Pathological Process.

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    N V Zotova

    Full Text Available We defined Systemic inflammation (SI as a "typical, multi-syndrome, phase-specific pathological process, developing from systemic damage and characterized by the total inflammatory reactivity of endotheliocytes, plasma and blood cell factors, connective tissue and, at the final stage, by microcirculatory disorders in vital organs and tissues." The goal of the work: to determine methodological approaches and particular methodical solutions for the problem of identification of SI as a common pathological process. SI can be defined by the presence in plasma of systemic proinflammatory cell stress products-cytokines and other inflammatory mediators, and also by the complexity of other processes signs. We have developed 2 scales: 1 The Reactivity Level scale (RL-from 0 to 5 points: 0-normal level; RL-5 confirms systemic nature of inflammatory mediator release, and RL- 2-4 defines different degrees of event probability. 2 The SI scale, considering additional criteria along with RL, addresses more integral criteria of SI: the presence of ≥ 5 points according to the SI scale proves the high probability of SI developing. To calculate the RL scale, concentrations of 4 cytokines (IL-6, IL-8, IL-10, TNF-α and C-reactive protein in plasma were examined. Additional criteria of the SI scale were the following: D-dimers>500ng/ml, cortisol>1380 or <100nmol/l, troponin I≥0.2ng/ml and/or myoglobin≥800ng/ml. 422 patients were included in the study with different septic (n-207 and aseptic (n-215 pathologies. In 190 cases (of 422 there were signs of SI (lethality 38.4%, n-73. In only 5 of 78 cases, lethality was not confirmed by the presence of SI. SI was registered in 100% of cases with septic shock (n-31. There were not significant differences between AU-ROC of CR, SI scale and SOFA to predict death in patients with sepsis and trauma.

  3. Methodological Approach to Determining the Effect of Parallel Energy Consumption on District Heating System

    Science.gov (United States)

    Latosov, Eduard; Volkova, Anna; Siirde, Andres; Kurnitski, Jarek; Thalfeldt, Martin

    2017-05-01

    District heating (DH) offers the most effective way to enhance the efficiency of primary energy use, increasing the share of renewable energy in energy consumption and decreasing the amount of CO2 emissions. According to Article 9 section 1 of the Directive 2010/31/EU of the European Parliament and of the Council of 19 May 2010 on the energy performance of buildings, the Member states of the European Union are obligated to draw up National Plans for increasing the number of nearly zero-energy buildings [1]. Article 2 section 2 of the same Directive states that the energy used in nearly zero-energy buildings should be created covered to a very significant extent by energy from renewable sources, including energy from renewable sources produced on-site or nearby. Thus, the heat distributed by DH systems and produced by manufacturing devices located in close vicinity of the building also have to be taken into account in determining the energy consumption of the building and the share of renewable energy used in the nearly zero-energy buildings. With regard to the spreading of nearly zero-energy and zero-energy houses, the feasibility of on-site energy (heat and/or electricity) production and consumption in DH areas energy (i.e. parallel consumption, when the consumer, connected to DH system, consumes energy for heat production from other sources besides the DH system as well) needs to be examined. In order to do that, it is necessary to implement a versatile methodological approach based on the principles discussed in this article.

  4. Methodological Approaches to Pedagogical Control in Physical Education of Girls Aged 12-14

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    О. Іващенко

    2016-12-01

    Full Text Available The objective is to determine the methodological approaches to pedagogical control in physical education of girls aged 12-14. Materials and methods. The participants of the study were girls aged 12 (n = 31, aged 13 (n = 26, and aged 14 (n = 28. To achieve the tasks set, the study relied on the following methods: analysis of scientific literature, pedagogical testing and methods of mathematical statistics. To evaluate the functional and motor preparedness of the girls aged 12-14, we recorded the results of Stange and Genchi, Serkin and motor tests. Results. The standardized coefficients of the canonical discriminant function allow to determine the relation of the variables contribution to the function result. The first function explains the results variation by 86.8% (p < 0.001, the second — by 13.2% (p < 0.001. The above proves that pedagogical control is possible in physical education based on the classification of the age differences in girls aged 12-14, by the results of their functional, strength and coordination preparedness tested. The structural coefficients of the first canonical discriminant function indicate that a significant difference between the girls aged 12 and the girls aged 13-14 occurs in the level of development of their motor coordination, speed strength and the results of Stange’s test. The structural coefficients of the second canonical discriminant function indicate that a significant difference between the girls aged 13 and 14 occurs in the level of development of the static and relative strength of their arm muscles. Conclusions. The final pedagogical control of motor and functional preparedness of the girls aged 12-14 can rest on the first discriminant function with emphasis on the most informative variables.

  5. A methodological approach to characterise Landslide Periods based on historical series of rainfall and landslide damage

    Directory of Open Access Journals (Sweden)

    O. Petrucci

    2009-10-01

    Full Text Available Landslide Periods (LPs are defined as periods, shorter than a hydrological year, during which one or more landslide damage events occur in one or more sectors of a study area. In this work, we present a methodological approach, based on the comparative analysis of historical series of landslide damage and daily rainfall data, aiming to characterise the main types of LPs affecting selected areas. Cumulative rainfall preceding landslide activation is assessed for short (1, 2, 3, and 5 days, medium (7, 10, and 30 days and long (60, 90, and 180 days durations, and their Return Periods (RPs are assessed and ranked into three classes (Class 1: RP=5-10 years; Class 2: RP=11-15; Class 3: RP>15 years. To assess landslide damage, the Simplified Damage Index (SDI is introduced. This represents classified landslide losses and is obtained by multiplying the value of the damaged element and the percentage of damage affecting it. The comparison of the RP of rainfall and the SDI allows us to indentify the different types of LPs that affected the study area in the past and that could affect it again in the future.

    The results of this activity can be used for practical purposes to define scenarios and strategies for risk management, to suggest priorities in policy towards disaster mitigation and preparedness and to predispose defensive measures and civil protection plans ranked according to the types of LPs that must be managed.

    We present an application, performed for a 39-year series of rainfall/landslide damage data and concerning a study area located in NE Calabria (Italy; in this case study, we identify four main types of LPs, which are ranked according to damage severity.

  6. Methodologies for the Extraction of Phenolic Compounds from Environmental Samples: New Approaches

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    Cristina Mahugo Santana

    2009-01-01

    Full Text Available Phenolic derivatives are among the most important contaminants present in the environment. These compounds are used in several industrial processes to manufacture chemicals such as pesticides, explosives, drugs and dyes. They also are used in the bleaching process of paper manufacturing. Apart from these sources, phenolic compounds have substantial applications in agriculture as herbicides, insecticides and fungicides. However, phenolic compounds are not only generated by human activity, but they are also formed naturally, e.g., during the decomposition of leaves or wood. As a result of these applications, they are found in soils and sediments and this often leads to wastewater and ground water contamination. Owing to their high toxicity and persistence in the environment, both, the US Environmental Protection Agency (EPA and the European Union have included some of them in their lists of priority pollutants. Current standard methods of phenolic compounds analysis in water samples are based on liquid–liquid extraction (LLE while Soxhlet extraction is the most used technique for isolating phenols from solid matrices. However, these techniques require extensive cleanup procedures that are time-intensive and involve expensive and hazardous organic solvents, which are undesirable for health and disposal reasons. In the last years, the use of news methodologies such as solid-phase extraction (SPE and solid-phase microextraction (SPME have increased for the extraction of phenolic compounds from liquid samples. In the case of solid samples, microwave assisted extraction (MAE is demonstrated to be an efficient technique for the extraction of these compounds. In this work we review the developed methods in the extraction and determination of phenolic derivatives in different types of environmental matrices such as water, sediments and soils. Moreover, we present the new approach in the use of micellar media coupled with SPME process for the

  7. Daniel Courgeau: Probability and social science: methodological relationships between the two approaches [Review of: . Probability and social science: methodological relationships between the two approaches

    NARCIS (Netherlands)

    Willekens, F.J.C.

    2013-01-01

    Throughout history, humans engaged in games in which randomness plays a role. In the 17th century, scientists started to approach chance scientifically and to develop a theory of probability. Courgeau describes how the relationship between probability theory and social sciences emerged and evolved f

  8. Towards better environmental performance of wastewater sludge treatment using endpoint approach in LCA methodology.

    Science.gov (United States)

    Alyaseri, Isam; Zhou, Jianpeng

    2017-03-01

    The aim of this study is to use the life cycle assessment method to measure the environmental performance of the sludge incineration process in a wastewater treatment plant and to propose an alternative that can reduce the environmental impact. To show the damages caused by the treatment processes, the study aimed to use an endpoint approach in evaluating impacts on human health, ecosystem quality, and resources due to the processes. A case study was taken at Bissell Point Wastewater Treatment Plant in Saint Louis, Missouri, U.S. The plant-specific data along with literature data from technical publications were used to build an inventory, and then analyzed the environmental burdens from sludge handling unit in the year 2011. The impact assessment method chosen was ReCipe 2008. The existing scenario (dewatering-multiple hearth incineration-ash to landfill) was evaluated and three alternative scenarios (fluid bed incineration and anaerobic digestion with and without land application) with energy recovery from heat or biogas were proposed and analyzed to find the one with the least environmental impact. The existing scenario shows that the most significant impacts are related to depletion in resources and damage to human health. These impacts mainly came from the operation phase (electricity and fuel consumption and emissions related to combustion). Alternatives showed better performance than the existing scenario. Using ReCipe endpoint methodology, and among the three alternatives tested, the anaerobic digestion had the best overall environmental performance. It is recommended to convert to fluid bed incineration if the concerns were more about human health or to anaerobic digestion if the concerns were more about depletion in resources. The endpoint approach may simplify the outcomes of this study as follows: if the plant is converted to fluid bed incineration, it could prevent an average of 43.2 DALYs in human life, save 0.059 species in the area from extinction

  9. Methodological study of computational approaches to address the problem of strong correlations

    Science.gov (United States)

    Lee, Juho

    The main focus of this thesis is the detailed investigation of computational methods to tackle strongly correlated materials in which a rich variety of exotic phenomena are found. A many-body problem with sizable electronic correlations can no longer be explained by independent-particle approximations such as density functional theory (DFT) or tight-binding approaches. The influence of an electron to the others is too strong for each electron to be treated as an independent quasiparticle and consequently those standard band-structure methods fail even at a qualitative level. One of the most powerful approaches for strong correlations is the dynamical mean-field theory (DMFT), which has enlightened the understanding of the Mott transition based on the Hubbard model. For realistic applications, the dynamical mean-field theory is combined with various independent-particles approaches. The most widely used one is the DMFT combined with the DFT in the local density approximation (LDA), so-called LDA+DMFT. In this approach, the electrons in the weakly correlated orbitals are calculated by LDA while others in the strongly correlated orbitals are treated by DMFT. Recently, the method combining DMFT with Hedin's GW approximation was also developed, in which the momentum-dependent self-energy is also added. In this thesis, we discuss the application of those methodologies based on DMFT. First, we apply the dynamical mean-field theory to solve the 3-dimensional Hubbard model in Chap. 3. In this application, we model the interface between the thermodynamically coexisting metal and Mott insulator. We show how to model the required slab geometry and extract the electronic spectra. We construct an effective Landau free energy and compute the variation of its parameters across the phase diagram. Finally, using a linear mixture of the density and double-occupancy, we identify a natural Ising order parameter which unifies the treatment of the bandwidth and filling controlled Mott

  10. Changes in the reflectance of ex situ leaves: A methodological approach

    Science.gov (United States)

    Ponzoni, Flavio Jorge; Inoe, Mario Takao

    1992-04-01

    The main aspects of the interaction between electromagnetic radiation and detached leaves are presented. An experiment with Eucalipto and Araucaria detached leaves is described, including the description of the methodologies utilized in the collection and storage of the reflectance.

  11. Transformation of theoretical-methodological approaches and methodical tools of the individual and territory welfare diagnostics. Part 1. From spreading to the alternative diagnostics approaches (background

    Directory of Open Access Journals (Sweden)

    Aleksandr Anatolyevich Kuklin

    2014-09-01

    Full Text Available This article presents an evolution of theoretical and methodological approaches to the welfare study. Existing theories of wellbeing are grouped according to accounted method of goods and resources distribution among society members. As a welfare future as a category we highlight objective (measured and subjective (estimated components. Based on the analysis of scientific literature we determine the ratio of individual and social welfare. The main differences between the categories of “ welfare” and “wealth” are given. The main difference consists in multidirectional changes of welfare and wealth for an increase (decrease in income of the individual (country. In this article we present an analysis of modern approaches to the definition of welfare: state, institutional and expendable approach. The welfare level estimation is complicated due to the need to consider the subjective component. The article provides an analysis of existing approaches to quantitative welfare evaluation ranging from the most common techniques (HDI, GDP to alternative techniques (Happy Planet Index.Methodological devices are structured by levels of welfare assessment objects (world, country, region, people. Based on the analysis of the advantages and disadvantages of methods we can conclude that the most reliable method is a comprehensive approach, which includes economic, environmental, social, vital and infrastructure indicators. The author’s approach to the formation of a complex methodological tool for individual and territory welfare estimation is presented in this article.

  12. Soft System Methodology as a Tool to Understand Issues of Governmental Affordable Housing Programme of India: A Case Study Approach

    Science.gov (United States)

    Ghosh, Sukanya; Roy, Souvanic; Sanyal, Manas Kumar

    2016-09-01

    With the help of a case study, the article has explored current practices of implementation of governmental affordable housing programme for urban poor in a slum of India. This work shows that the issues associated with the problems of governmental affordable housing programme has to be addressed to with a suitable methodology as complexities are not only dealing with quantitative data but qualitative data also. The Hard System Methodologies (HSM), which is conventionally applied to address the issues, deals with real and known problems which can be directly solved. Since most of the issues of affordable housing programme as found in the case study are subjective and complex in nature, Soft System Methodology (SSM) has been tried for better representation from subjective points of views. The article explored drawing of Rich Picture as an SSM approach for better understanding and analysing complex issues and constraints of affordable housing programme so that further exploration of the issues is possible.

  13. Towards more sustainable management of European food waste: Methodological approach and numerical application.

    Science.gov (United States)

    Manfredi, Simone; Cristobal, Jorge

    2016-09-01

    Trying to respond to the latest policy needs, the work presented in this article aims at developing a life-cycle based framework methodology to quantitatively evaluate the environmental and economic sustainability of European food waste management options. The methodology is structured into six steps aimed at defining boundaries and scope of the evaluation, evaluating environmental and economic impacts and identifying best performing options. The methodology is able to accommodate additional assessment criteria, for example the social dimension of sustainability, thus moving towards a comprehensive sustainability assessment framework. A numerical case study is also developed to provide an example of application of the proposed methodology to an average European context. Different options for food waste treatment are compared, including landfilling, composting, anaerobic digestion and incineration. The environmental dimension is evaluated with the software EASETECH, while the economic assessment is conducted based on different indicators expressing the costs associated with food waste management. Results show that the proposed methodology allows for a straightforward identification of the most sustainable options for food waste, thus can provide factual support to decision/policy making. However, it was also observed that results markedly depend on a number of user-defined assumptions, for example on the choice of the indicators to express the environmental and economic performance.

  14. The methodological competence of the teacher of foreign languages from a configurational approach

    Directory of Open Access Journals (Sweden)

    ALBERTO ROMÁN MEDINA BETANCOURT

    2013-11-01

    Full Text Available This article shows a proposal of the definition of what is meant by methodological competence for foreign language teaching from a configurational perspective. A definition is given to the term competence and from this definition, the content of methodological competence was determined through the subcompetences that foreign language teachers should have in order to be considered competent from the methodological stand point. The results which are presented in the article might be considered very useful, both from the theoretical and from the practical points of view. They can be used as a guide for the preparation of teachers with the aim of obtaining higher levels of efficiency in the formation and development of the verbal skills in foreign languages in his students. Such a goal is of great importance nowadays all over the world.  

  15. Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach.

    Science.gov (United States)

    Aromataris, Edoardo; Fernandez, Ritin; Godfrey, Christina M; Holly, Cheryl; Khalil, Hanan; Tungpunkom, Patraporn

    2015-09-01

    With the increase in the number of systematic reviews available, a logical next step to provide decision makers in healthcare with the evidence they require has been the conduct of reviews of existing systematic reviews. Syntheses of existing systematic reviews are referred to by many different names, one of which is an umbrella review. An umbrella review allows the findings of reviews relevant to a review question to be compared and contrasted. An umbrella review's most characteristic feature is that this type of evidence synthesis only considers for inclusion the highest level of evidence, namely other systematic reviews and meta-analyses. A methodology working group was formed by the Joanna Briggs Institute to develop methodological guidance for the conduct of an umbrella review, including diverse types of evidence, both quantitative and qualitative. The aim of this study is to describe the development and guidance for the conduct of an umbrella review. Discussion and testing of the elements of methods for the conduct of an umbrella review were held over a 6-month period by members of a methodology working group. The working group comprised six participants who corresponded via teleconference, e-mail and face-to-face meeting during this development period. In October 2013, the methodology was presented in a workshop at the Joanna Briggs Institute Convention. Workshop participants, review authors and methodologists provided further testing, critique and feedback on the proposed methodology. This study describes the methodology and methods developed for the conduct of an umbrella review that includes published systematic reviews and meta-analyses as the analytical unit of the review. Details are provided regarding the essential elements of an umbrella review, including presentation of the review question in a Population, Intervention, Comparator, Outcome format, nuances of the inclusion criteria and search strategy. A critical appraisal tool with 10 questions to

  16. Historical and methodological approach to music education courses at the Universitat de les Illes Balears (1977-1990

    Directory of Open Access Journals (Sweden)

    Llorenç GELABERT GUAL

    2016-10-01

    Full Text Available The education in general and the music in particular were not outside to the changes developed in Spain in the seventies of last century. The initiative, in the form of summer courses, promoted by a group of teachers and musicians, will mean the beginning of a true outcrop in music education, and will get in crescendo. This new concept is based on active methodologies successfully applied in other European countries and their linkage with the learning environment of the Catalan musician Ireneu Segarra, in the line of great figures of the musical avantgarde. This article is intended to approach the legacy of these courses from two perspectives. First, from a historical point of view, and then reaching any specific methodological applications then initiated. Finally, this article intends to approach his legacy highlighting the potential and utility also could acquire a similar format nowadays, in the new adaptation framework to EHEA.

  17. Application of methodological approach to selection of sportswomen to calisthenics teams for group exercises, considering compatibility factor

    Directory of Open Access Journals (Sweden)

    Kozhanova O.S.

    2015-04-01

    Full Text Available Purpose: motivation of methodological approach to selection of sportswomen to calisthenics teams for group exercises considering compatibility factor. Material: in the research 40 high qualification sportswomen of 17-23 yrs age with sport experience of 11-16 years participated. With cluster analysis 10 gymnasts with morphological indicators, meeting modern standards of group exercises were selected. Results: we found 5 generalized factors, which characterize structure of selection to teams and determines 72% of dispersion. Influence of kinds and connected with them criteria of compatibility on efficiency of gymnasts’ competition functioning were also determined. The authors substantiated methodological approach to selection of sportswomen to calisthenics teams for group exercises, considering compatibility factor. Conclusions: in selection to calisthenics teams for group exercises it is purposeful to realize complex registration of compatibility kinds, considering gymnasts’ similar features by recommended indicators.

  18. A methodological approach for working with families in suas: a critical reading through the lens of citizenship

    Directory of Open Access Journals (Sweden)

    Maria Lucia Miranda Afonso

    2013-01-01

    Full Text Available The paper reviews the current National Policy of Social Welfare in Brazil and the work developed with families within the Brazilian social protection approach. It describes the Unified System of Social Welfare and explores the relationship of the Basic Social Protection to the Bolsa Família Program, the Brazilian program of conditional cash transfer to vulnerable families. It discusses the principles of the methodology for working with vulnerable families in the Unified System of Social Welfare and analyzes examples of social interventions. It argues that the work developed with families must be based on participatory and dialogical approaches, including follow-up methods, group dynamics, action-research, and other interventions. The paper concludes with questions regarding the use of a socio-educational methodology as a component of policies for vulnerability reduction, social development and the promotion of citizenship.

  19. Quantifying the health impacts of air pollution under a changing climate—a review of approaches and methodology

    OpenAIRE

    Sujaritpong, Sarunya; Dear, Keith; Cope, Martin; Walsh, Sean; Kjellstrom, Tord

    2013-01-01

    Climate change has been predicted to affect future air quality, with inevitable consequences for health. Quantifying the health effects of air pollution under a changing climate is crucial to provide evidence for actions to safeguard future populations. In this paper, we review published methods for quantifying health impacts to identify optimal approaches and ways in which existing challenges facing this line of research can be addressed. Most studies have employed a simplified methodology, ...

  20. Designing with Space Syntax: A configurative approach to architectural layout, proposing a computational methodology

    NARCIS (Netherlands)

    Nourian, P.; Rezvani, S.; Sariyildiz, I.S.

    2013-01-01

    This paper introduces a design methodology and a toolkit developed as a parametric CAD program for configurative design of architectural plan layouts. Using this toolkit, designers can start plan layout process with sketching the way functional spaces need to connect to each other. A tool draws an i

  1. A collaborative approach to mapping value of fisheries resources in the North Sea (Part 1: Methodology)

    NARCIS (Netherlands)

    Hintzen, N.T.; Coers, A.; Hamon, K.

    2013-01-01

    IMARES and LEI are both contracted on occasion to perform VMS-analyses to produce maps of fishing activity or economic value of fisheries in particular area(s) in the North Sea. Until present, IMARES and LEI use their own methodology which is inspired mostly on their own unique data availabilities w

  2. On the Quality of Global Emission Inventories : Approaches, Methodologies, Input Data and Uncertainties

    NARCIS (Netherlands)

    Olivier, Johannes Gerardus Jozef

    2002-01-01

    This thesis deals with methodological and practical aspects of compiling global emission inventories in relation to their use. The first part of the thesis describes quality aspects from the perspective of the user: i.e. definition, determining factors, practical applications and quantitative

  3. Methodological approaches to the assessment of the competitiveness of the region

    Directory of Open Access Journals (Sweden)

    Nazarov Nikolai Igorevich

    2013-03-01

    Full Text Available This paper presents the results of research methodologies for assessing the competitiveness of the region based on the analysis of literary sources. The study stated the author's technique assessing the competitiveness of the region, in accordance with the paradigm of regional development.

  4. Environmental failure mode and effects analysis (FMEA – a new approach to methodology

    Directory of Open Access Journals (Sweden)

    M. Roszak

    2015-04-01

    Full Text Available The purpose of this paper is to present a concept of FMEA analysis for environmental aspects, together with a discussion of the importance, implementation and application of the proposed concept. The analyses and the developed E-FMEA methodology have resulted in a proposal of management tools for manufacturing processes.

  5. An approach to SOA development methodology: SOUP comparison with RUP and XP

    Directory of Open Access Journals (Sweden)

    Sandra Svanidzaitė

    2014-08-01

    Full Text Available Service oriented architecture (SOA is an architecture for distributed applications composed of distributed services with weak coupling that are designed to meet business requirements. One of the research priorities in the field of SOA is creating such software design and development methodology (SDDM that takes into account all principles of this architecture and allows for effective and efficient application development. A lot of investigation has been carried out to find out whether can one of popular SDDM, such as agile methodologies or RUP suits, be adapted for SOA or there is a need to create some new SOA-oriented SDDM. This paper compares one of SOA-oriented SDDM – SOUP – with RUP and XP methodologies. The aim is to find out whether the SOUP methodology is already mature enough to assure successful development of SOA applications. This aim is accomplished by comparing activities, artifacts of SOUP and RUP and emphasizing which XP practices are used in SOUP.DOI: http://dx.doi.org/10.15181/csat.v2i1.77 

  6. A collaborative approach to mapping value of fisheries resources in the North Sea (Part 1: Methodology)

    NARCIS (Netherlands)

    Hintzen, N.T.; Coers, A.; Hamon, K.

    2013-01-01

    IMARES and LEI are both contracted on occasion to perform VMS-analyses to produce maps of fishing activity or economic value of fisheries in particular area(s) in the North Sea. Until present, IMARES and LEI use their own methodology which is inspired mostly on their own unique data availabilities w

  7. Goals and Methodology for a Surgery Residency Program: A Committee Approach.

    Science.gov (United States)

    Knecht, Charles D.; And Others

    1979-01-01

    Written goals of a small animal residency program established by Purdue University are identified and an elaborate list of methodology for goals is provided. Tables include: summary of required activities of residents, checklist of residency progress, and comparable effort for surgery residency and masters program. (Author/MLW)

  8. Methodological approaches for the molecular characterization on refractory organic matter forms in marine sediments

    OpenAIRE

    2003-01-01

    1 página. Poster contributions- SO-81 presentado en el VIII International symposium on analytical methodology in the environmental field. XIII Reunión de la Sociedad española de química analítica, VIII ISAMEF/SEQA 2003. University of A Coruña October 21-24, 2003.

  9. Methodological approaches for the molecular characterization on refractory organic matter forms in marine sediments

    OpenAIRE

    González-Vila, Francisco Javier; González-Pérez, José Antonio; Polvillo, Oliva

    2003-01-01

    1 página. Poster contributions- SO-81 presentado en el VIII International symposium on analytical methodology in the environmental field. XIII Reunión de la Sociedad española de química analítica, VIII ISAMEF/SEQA 2003. University of A Coruña October 21-24, 2003.

  10. Theoretical Significance in Q Methodology: A Qualitative Approach to a Mixed Method

    Science.gov (United States)

    Ramlo, Susan

    2015-01-01

    Q methodology (Q) has offered researchers a unique scientific measure of subjectivity since William Stephenson's first article in 1935. Q's focus on subjectivity includes self-referential meaning and interpretation. Q is most often identified with its technique (Q-sort) and its method (factor analysis to group people); yet, it consists of a…

  11. Computerized approaches to enhance understanding of organic reaction mechanisms: CAN reaction mechanisms and CPLEX prelaboratory methodology

    Science.gov (United States)

    Al-Shammari, Abdulrahman G. Alhamzani

    2008-10-01

    Two approaches to enhance the understanding of organic reaction mechanisms are described. First, a new method for teaching organic reaction mechanisms that can be used in a Computer-Assisted Instruction (CAI) environment is proposed and tested (Chapter 1). The method concentrates upon the important intermediate structures, which are assumed to be on the reaction coordinate, and which can be evaluated and graded by currently available computer techniques. At the same time, the "curved arrows" that show the electron flow in a reaction mechanism are neglected, since they cannot be evaluated and graded with currently available computer techniques. By allowing student practice for learning organic reaction mechanisms using the Curved Arrow Neglect (CAN) method within a "Practice Makes Perfect" CAI method, student performance in the drawing of traditional reaction mechanisms, in which students had to include the "curved arrows" on their written classroom exams, was significantly enhanced. Second, computerized prelaboratory experiments (CPLEX) for organic chemistry laboratory 1 & 2 courses have been created, used, and evaluated (Chapters 2 and 3). These computerized prelabs are unique because they combine both "dry lab" actions with detailed animations of the actual chemistry occurring at the molecular level. The "dry lab" serves to simulate the actual physical manipulations of equipment and chemicals that occur in the laboratory experiment through the use of drag-and-drop computer technology. At the same time, these physical actions are accompanied on a separate part of the computer screen by animations showing the chemistry at the molecular level that is occurring in the experiment. These CPLEX modules were made into Internet accessible modules. The students were allowed to access the CPLEX modules prior to performing the actual laboratory experiment. A detailed evaluation of students' perception of the modules was accomplished via survey methodology during the entire

  12. Scientific and methodological tools of cost management of enterprises: the main approaches and proposals

    Directory of Open Access Journals (Sweden)

    M. S. Dikunova

    2017-01-01

    and analyzed the functionality of the system of supply and distribution that helped to create an element base for our study.In addition, the structural parts of the supply and marketing systems are defined that need to work in the process of cost management in industrial and defense industries.It was found that for creation of the effective, scientific-methodical instrument of cost management for supply and distribution it is necessary to study the main approaches, identifying the strengths and weaknesses of each. Besides, principles and methods are different when functioning of the strategic and operational levels of the management costs.Thus, the solution of the scientific task will be to study and develop the scientific methodology of cost management in industrial enterprises and enterprises of the military-industrial complex, essential for the solution of problems of pricing and optimization of production processes.

  13. Soft systems methodology and the ecosystem approach: a system study of the Cooum River and environs in Chennai, India.

    Science.gov (United States)

    Bunch, Martin J

    2003-02-01

    This paper discusses the integration of soft systems methodology (SSM) within an ecosystem approach in research to support rehabilitation and management of the Cooum River and environs in Chennai, India. The Cooum is an extremely polluted urban stream. Its management is complicated by high rates of population growth, poverty, uncontrolled urban development, jurisdictional conflicts, institutional culture, flat topography, tidal action, blockage of the river mouth, and monsoon flooding. The situation is characterized by basic uncertainty about main processes and activities, and the nature of relationships among actors and elements in the system.SSM is an approach for dealing with messy or ill-structured problematic situations involving human activity. In this work SSM contributed techniques (such as "rich picture" and "CATWOE" tools) to description of the Cooum situation as a socioecological system and informed the approach itself at a theoretical level. Application of three general phases in SSM is discussed in the context of the Cooum River research: (1) problem definition and exploration of the problem situation, (2) development of conceptual models of relevant systems, and (3) the use of these to generate insight and stimulate debate about desirable and feasible change. Its use here gives weight to the statement by others that SSM would be a particularly appropriate methodology to operate the ecosystem approach. As well as informing efforts at management of the Cooum system, this work led the way to explore an adaptive ecosystem approach more broadly to management of the urban environment for human health in Chennai.

  14. Methodological Approaches to Management Systems Examination in Terms of Financial Crisis

    Directory of Open Access Journals (Sweden)

    Irina N. Markaryan

    2011-11-01

    Full Text Available The article is concerned with existing approaches to management systems examination in terms of financial crisis, brings in general approaches to companies’ management systems analysis, considers different decision making methods in terms of companies’ management system.

  15. Methodological Approaches to Management Systems Examination in Terms of Financial Crisis

    OpenAIRE

    Irina N. Markaryan

    2011-01-01

    The article is concerned with existing approaches to management systems examination in terms of financial crisis, brings in general approaches to companies’ management systems analysis, considers different decision making methods in terms of companies’ management system.

  16. Regional studies program. Forecasting the local economic impacts of energy resource development: a methodological approach

    Energy Technology Data Exchange (ETDEWEB)

    Stenehjem, E.J.

    1975-12-01

    Emphasis is placed on the nature and magnitude of socio-economic impacts of fossil-fuel development. A model is described that identifies and estimates the magnitude of the economic impacts of anticipated energy resource development in site-specific areas and geographically contiguous areas of unspecified size. The modeling methodology was designed to assist industries and government agencies complying with recent federal and state legislation requiring subregional impact analyses for individual facilities. The model was designed in light of the requirements for accuracy, expandability, and exportability. The methodology forecasts absolute increments in local and regional growth on an annual or biennial basis and transforms these parameters into estimates of the affected area's ability to accommodate growth-induced demands, especially demands for public services. (HLW)

  17. A methodological approach to the design of optimising control strategies for sewer systems

    DEFF Research Database (Denmark)

    Mollerup, Ane Loft; Mikkelsen, Peter Steen; Sin, Gürkan

    2016-01-01

    This study focuses on designing an optimisation based control for sewer system in a methodological way and linking itto a regulatory control. Optimisation based design is found to depend on proper choice of a model, formulation of objective function and tuning of optimisation parameters. Accordin......This study focuses on designing an optimisation based control for sewer system in a methodological way and linking itto a regulatory control. Optimisation based design is found to depend on proper choice of a model, formulation of objective function and tuning of optimisation parameters...... control; a rule based expert system. On the other hand, compared with a regulatory control technique designed earlier in Mollerup et al. (2015), the optimisation showed similar performance with respect to minimising overflow volume. Hence for operation of small sewer systems, regulatory control strategies...... can offer promising potential and should be considered along more advanced strategies when identifying novel solutions....

  18. Putting phylogeny into the analysis of biological traits: a methodological approach.

    Science.gov (United States)

    Jombart, Thibaut; Pavoine, Sandrine; Devillard, Sébastien; Pontier, Dominique

    2010-06-01

    Phylogenetic comparative methods have long considered phylogenetic signal as a source of statistical bias in the correlative analysis of biological traits. However, the main life-history strategies existing in a set of taxa are often combinations of life history traits that are inherently phylogenetically structured. In this paper, we present a method for identifying evolutionary strategies from large sets of biological traits, using phylogeny as a source of meaningful historical and ecological information. Our methodology extends a multivariate method developed for the analysis of spatial patterns, and relies on finding combinations of traits that are phylogenetically autocorrelated. Using extensive simulations, we show that our method efficiently uncovers phylogenetic structures with respect to various tree topologies, and remains powerful in cases where a large majority of traits are not phylogenetically structured. Our methodology is illustrated using empirical data, and implemented in the adephylo package for the free software R.

  19. Methodological Challenges to Economic Evaluations of Vaccines: Is a Common Approach Still Possible?

    Science.gov (United States)

    Jit, Mark; Hutubessy, Raymond

    2016-06-01

    Economic evaluation of vaccination is a key tool to inform effective spending on vaccines. However, many evaluations have been criticised for failing to capture features of vaccines which are relevant to decision makers. These include broader societal benefits (such as improved educational achievement, economic growth and political stability), reduced health disparities, medical innovation, reduced hospital beds pressures, greater peace of mind and synergies in economic benefits with non-vaccine interventions. Also, the fiscal implications of vaccination programmes are not always made explicit. Alternative methodological frameworks have been proposed to better capture these benefits. However, any broadening of the methodology for economic evaluation must also involve evaluations of non-vaccine interventions, and hence may not always benefit vaccines given a fixed health-care budget. The scope of an economic evaluation must consider the budget from which vaccines are funded, and the decision-maker's stated aims for that spending to achieve.

  20. Kids, Adolescents, and Young Adults Cancer Study—A Methodologic Approach in Cancer Epidemiology Research

    Directory of Open Access Journals (Sweden)

    Nancy J. Link

    2009-01-01

    Full Text Available Advances have been made in treatment and outcomes for pediatric cancer. However adolescents and young adults (AYAs with cancer have not experienced similar relative improvements. We undertook a study to develop the methodology necessary for epidemiologic cancer research in these age groups. Our goal was to create the Kids, Adolescents, and Young Adults Cancer (KAYAC project to create a resource to address research questions relevant to this population. We used a combination of clinic and population-based ascertainment to enroll 111 cases aged 0–39 for this methodology development study. The largest groups of cancer types enrolled include: breast cancer, leukemia, lymphoma, and melanoma. The overall participation rate is 69.8% and varies by age and tumor type. The study included patients, mothers, and fathers. The methods used to establish this resource are described, and the values of the resource in studies of childhood and young adult cancer are outlined.

  1. Exposing diversity:a methodological approach to the use of video in interdisciplinary practices

    OpenAIRE

    Jakobsen, Helle Nordentoft; Nørtoft, Kamilla Pernille Johansen

    2015-01-01

    Video has been used extensively in professional practices to qualify communication processes. However, there has been little investigation and theorization of the interplay between the methodological use of video and how it contributes to collaborative learning processes. The purpose of this paper is to introduce an analytical framework for using video in collaborative learning processes in an interdisciplinary context. Interdisciplinary collaboration has been pointed out as one of the most i...

  2. Using Response Surface Methodology as an Approach to Understand and Optimize Operational Air Power

    Science.gov (United States)

    2010-01-01

    Introduction to Taguchi Methodology. In Taguchi Methods : Proceedings of the 1988 European Conference, 1-14. London: Elsevier Applied Science. Box G. E. and N...Parameter Design, and the Taguchi Method . Journal of Quality Technology 17(4):176-188. Kometer, Michael W. 2005. Command in Air War: Centralized vs...1989. Quality Engineering Using Robust Design. Englewood Cliffs, NJ: Prentice Hall. Ranjit R. 1990. A Primer on the Taguchi Method . New York, NY: Van

  3. Methodological approach for the collection and simultaneous estimation of greenhouse gases emission from aquaculture ponds.

    Science.gov (United States)

    Vasanth, Muthuraman; Muralidhar, Moturi; Saraswathy, Ramamoorthy; Nagavel, Arunachalam; Dayal, Jagabattula Syama; Jayanthi, Marappan; Lalitha, Natarajan; Kumararaja, Periyamuthu; Vijayan, Koyadan Kizhakkedath

    2016-12-01

    Global warming/climate change is the greatest environmental threat of our time. Rapidly developing aquaculture sector is an anthropogenic activity, the contribution of which to global warming is little understood, and estimation of greenhouse gases (GHGs) emission from the aquaculture ponds is a key practice in predicting the impact of aquaculture on global warming. A comprehensive methodology was developed for sampling and simultaneous analysis of GHGs, carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) from the aquaculture ponds. The GHG fluxes were collected using cylindrical acrylic chamber, air pump, and tedlar bags. A cylindrical acrylic floating chamber was fabricated to collect the GHGs emanating from the surface of aquaculture ponds. The sampling methodology was standardized and in-house method validation was established by achieving linearity, accuracy, precision, and specificity. GHGs flux was found to be stable at 10 ± 2 °C of storage for 3 days. The developed methodology was used to quantify GHGs in the Pacific white shrimp Penaeus vannamei and black tiger shrimp Penaeus monodon culture ponds for a period of 4 months. The rate of emission of carbon dioxide was found to be much greater when compared to other two GHGs. Average GHGs emission in gha(-1) day(-1) during the culture was comparatively high in P.vannamei culture ponds.

  4. Source-water susceptibility assessment in Texas—Approach and methodology

    Science.gov (United States)

    Ulery, Randy L.; Meyer, John E.; Andren, Robert W.; Newson, Jeremy K.

    2011-01-01

    Public water systems provide potable water for the public's use. The Safe Drinking Water Act amendments of 1996 required States to prepare a source-water susceptibility assessment (SWSA) for each public water system (PWS). States were required to determine the source of water for each PWS, the origin of any contaminant of concern (COC) monitored or to be monitored, and the susceptibility of the public water system to COC exposure, to protect public water supplies from contamination. In Texas, the Texas Commission on Environmental Quality (TCEQ) was responsible for preparing SWSAs for the more than 6,000 public water systems, representing more than 18,000 surface-water intakes or groundwater wells. The U.S. Geological Survey (USGS) worked in cooperation with TCEQ to develop the Source Water Assessment Program (SWAP) approach and methodology. Texas' SWAP meets all requirements of the Safe Drinking Water Act and ultimately provides the TCEQ with a comprehensive tool for protection of public water systems from contamination by up to 247 individual COCs. TCEQ staff identified both the list of contaminants to be assessed and contaminant threshold values (THR) to be applied. COCs were chosen because they were regulated contaminants, were expected to become regulated contaminants in the near future, or were unregulated but thought to represent long-term health concerns. THRs were based on maximum contaminant levels from U.S. Environmental Protection Agency (EPA)'s National Primary Drinking Water Regulations. For reporting purposes, COCs were grouped into seven contaminant groups: inorganic compounds, volatile organic compounds, synthetic organic compounds, radiochemicals, disinfection byproducts, microbial organisms, and physical properties. Expanding on the TCEQ's definition of susceptibility, subject-matter expert working groups formulated the SWSA approach based on assumptions that natural processes and human activities contribute COCs in quantities that vary in space

  5. Methodological Approaches to Evaluate Teratogenic Risk Using Birth Defect Registries: Advantages and Disadvantages

    OpenAIRE

    Poletta, Fernando A.; López Camelo, Jorge S.; Gili, Juan A.; Emmanuele Leoncini; CASTILLA, EDUARDO E.; Pierpaolo Mastroiacovo

    2012-01-01

    BACKGROUND: Different approaches have been used in case-control studies to estimate maternal exposure to medications and the risk of birth defects. However, the performance of these approaches and how they affect the odds ratio (OR) estimates have not been evaluated using birth-defect surveillance programmes. The aim of this study was to evaluate the scope and limitations of three case-control approaches to assess the teratogenic risk of birth defects in mothers exposed to antiepileptic medic...

  6. An integrated approach to safety-driven and ICT-enabled process reengineering: methodological advice and a case study.

    Science.gov (United States)

    Langer, M; Castellari, R; Locatelli, P; Sini, E; Torresani, M; Facchini, R; Moser, R

    2014-01-01

    Patient safety is a central concern inside any healthcare environment. With the progress of Information and Communication Technologies (ICTs), new solutions have become available to support care and management processes. Analyzing process risks helps identifying areas of improvement and provides ICT-solutions design with indications on what portions of the process need primary interventions. Understanding the link between process reengineering, technology assessment of enabling technologies and risk management allows user acceptance and patient safety improvements. Fondazione IRCCS Istituto Nazionale dei Tumori (INT), offers a good example of process reengineering driven by the purpose of increasing patient safety, enabled by new technologies. A pillar of the evolution of ICT process support at INT is based on Radio Frequency Identification technologies, implemented to identify and trace items and people across processes. This paper will present an integrated approach, based on process reengineering methodologies and risk assessment studies, and methodological advice applied to a case of surgical kits management procedures.

  7. Methodology to characterize a residential building stock using a bottom-up approach: a case study applied to Belgium

    Directory of Open Access Journals (Sweden)

    Samuel Gendebien

    2014-06-01

    Full Text Available In the last ten years, the development and implementation of measures to mitigate climate change have become of major importance. In Europe, the residential sector accounts for 27% of the final energy consumption [1], and therefore contributes significantly to CO2 emissions. Roadmaps towards energy-efficient buildings have been proposed [2]. In such a context, the detailed characterization of residential building stocks in terms of age, type of construction, insulation level, energy vector, and of evolution prospects appears to be a useful contribution to the assessment of the impact of implementation of energy policies. In this work, a methodology to develop a tree-structure characterizing a residential building stock is presented in the frame of a bottom-up approach that aims to model and simulate domestic energy use. The methodology is applied to the Belgian case for the current situation and up to 2030 horizon. The potential applications of the developed tool are outlined.

  8. Application of the Spanish methodological approach for biosphere assessment to a generic high-level waste disposal site.

    Science.gov (United States)

    Agüero, A; Pinedo, P; Simón, I; Cancio, D; Moraleda, M; Trueba, C; Pérez-Sánchez, D

    2008-09-15

    A methodological approach which includes conceptual developments, methodological aspects and software tools have been developed in the Spanish context, based on the BIOMASS "Reference Biospheres Methodology". The biosphere assessments have to be undertaken with the aim of demonstrating compliance with principles and regulations established to limit the possible radiological impact of radioactive waste disposals on human health and on the environment, and to ensure that future generations will not be exposed to higher radiation levels than those that would be acceptable today. The biosphere in the context of high-level waste disposal is defined as the collection of various radionuclide transfer pathways that may result in releases into the surface environment, transport within and between the biosphere receptors, exposure of humans and biota, and the doses/risks associated with such exposures. The assessments need to take into account the complexity of the biosphere, the nature of the radionuclides released and the long timescales considered. It is also necessary to make assumptions related to the habits and lifestyle of the exposed population, human activities in the long term and possible modifications of the biosphere. A summary on the Spanish methodological approach for biosphere assessment are presented here as well as its application in a Spanish generic case study. A reference scenario has been developed based on current conditions at a site located in Central-West Spain, to indicate the potential impact to the actual population. In addition, environmental change has been considered qualitatively through the use of interaction matrices and transition diagrams. Unit source terms of (36)Cl, (79)Se, (99)Tc, (129)I, (135)Cs, (226)Ra, (231)Pa, (238)U, (237)Np and (239)Pu have been taken. Two exposure groups of infants and adults have been chosen for dose calculations. Results are presented and their robustness is evaluated through the use of uncertainty and

  9. Study of dental occlusion in ancient human remains: a methodological approach.

    Science.gov (United States)

    Fiorin, Elena; Cadafalch, Joan; Ceperuelo, Dolors; Adserias Adserias, Maria José; Chimenos-Küstner, Eduard; Malgosa, Assumpció

    2014-09-01

    The anthropological dental and maxillary study in human skeletal remains usually refers to alterations or conditions of the oral cavity. These alterations could have repercussions on life style, dietary habits and diseases. In this particular context, dental occlusion is not often analyzed due to the fragmented condition of the remains, and especially due to the lack of methodology adapted to study ancient remains. The aim of this study is to propose an anthropological method based on clinical dental practice. In the method presented in this work, odontological parameters such as overjet, overbite, and Angle's Classification of Malocclusion, are evaluated.

  10. Small Works, Big Stories. Methodological approaches to photogrammetry through crowd-sourcing experiences

    Directory of Open Access Journals (Sweden)

    Seren Griffiths

    2015-12-01

    Full Text Available A recent digital public archaeology project (HeritageTogether sought to build a series of 3D ditigal models using photogrammetry from crowd-sourced images. The project saw over 13000 digital images being donated, and resulted in models of some 78 sites, providing resources for researchers, and condition surveys. The project demonstrated that digital public archaeology does not stop at the 'trowel's edge', and that collaborative post-excavation analysis and generation of research processes are as important as time in the field. We emphasise in this contribution that our methodologies, as much as our research outputs, can be fruitfully co-produced in public archaeology projects.

  11. Product Service Systems and Non-Market Oriented ApproachMethodological and Ethical Considerations from a Design Perspective

    DEFF Research Database (Denmark)

    Morelli, Nicola; Jonas, Wolfgang; Munch, Juliane

    2008-01-01

    Macroscopic social and economic changes in the last few years are forcing business companies and public institutions to redefine their approach to social intervention, focusing on local and highly individualised solutions. This change is also calling for a new design approach. The challenge...... how this process was developed in a concrete case. Through this case the authors analyse the possibility to build something similar to a source code for initiatives based on social interaction and investigate the process of construction of such a code Furthermore, the author discuss differences...... and analogies between design intervention in a social context and in the normal business context. The question of codification suggests a methodological approach for supporting transferability both in the problem space (dealing with complexity) and in the solution space (dealing with contingency). The analysis...

  12. A Methodological Approach to Evaluate Livestock Innovations on Small-Scale Farms in Developing Countries

    Directory of Open Access Journals (Sweden)

    Antón García-Martínez

    2016-06-01

    Full Text Available The aim of the study was deepening the knowledge of livestock innovations knowledge on small-scale farms in developing countries. First, we developed a methodology focused on identifying potential appropriate livestock innovations for smallholders and grouped them in innovation areas, defined as a set of well-organized practices with a business purpose. Finally, a process management program (PMP was evaluated according to the livestock innovation level and viability of the small-scale farms. Logistic regression was used to evaluate the impact of PMP on the economic viability of the farm. Information from 1650 small-scale livestock farms in Mexico was collected and the innovations were grouped in five innovation areas: A1. Management, A2. Feeding, A3. Genetic, A4. Reproduction and A5. Animal Health. The resulting innovation level in the system was low at 45.7% and heterogeneous among areas. This study shows the usefulness of the methodology described and confirms that implementing a PMP allows improving the viability an additional 21%, due to a better integration of processes, resulting in more efficient management.

  13. Conceptual Demand of Practical Work in Science Curricula. A Methodological Approach

    Science.gov (United States)

    Ferreira, Sílvia; Morais, Ana M.

    2014-02-01

    This article addresses the issue of the level of complexity of practical work in science curricula and is focused on the discipline of Biology and Geology at high school. The level of complexity is seen in terms of the emphasis on and types of practical work and, most importantly, in terms of its level of conceptual demand as given by the complexity of scientific knowledge, the degree of inter-relation between knowledges, and the complexity of cognitive skills. The study also analyzes recontextualizing processes that may occur within the official recontextualizing field. The study is psychologically and sociologically grounded, particularly on Bernstein's theory of pedagogic discourse. It uses a mixed methodology. The results show that practical work is poorly represented in the curriculum, particularly in the case of laboratory work. The level of conceptual demand of practical work varies according to the text under analysis, between the two subjects Biology and Geology, and, within each of them, between general and specific guidelines. Aspects studied are not clearly explicated to curriculum receivers (teachers and textbooks authors). The meaning of these findings is discussed in the article. In methodological terms, the study explores assumptions used in the analysis of the level of conceptual demand and presents innovative instruments constructed for developing this analysis.

  14. PAGIS summary report of phase 1: a common methodological approach based on European data and models

    Energy Technology Data Exchange (ETDEWEB)

    Cadelli, N.; Cottone, G.; Bertozzi, G.; Girardi, F.

    1984-01-01

    Since 1982 a joint study has been launched by the CEC with the participation of national institutions in the E.C., aiming at a Performance Assessment of Geological Isolation Systems (PAGIS) for HLW disposal. This document is a summary of the first phase of the study which was devoted to the collection of data and models and to the choice of an appropriate methodology. To this purpose, real or national sites have been chosen, which are representative of three types of continental geological formations in the E.C.: clay, granite and salt (although the choices imply no committment of any kind about their final use). Moreover, sub-seabed areas have also been identified. The study covers the following items: - basic data on waste characteristics, site data and repository designs; - methodology, which allows sensitivity and uncertainty analyses to be performed, as well as the assessment of radiation doses to individuals and populations; - preliminary modelling of radionuclide release and migration through the geosphere (near- and far-field) and the biosphere following their various pathways to man; - selection of the most relevant radionuclide release scenarios and their probability of occurrence. Reference values have been selected for the basic data as well as variants covering the various options which are under consideration in the different Countries of the E.C.

  15. Methodology of synchronization among strategy and operation. A standards-based modeling approach

    Directory of Open Access Journals (Sweden)

    VICTOR EDWIN COLLAZOS

    2017-05-01

    Full Text Available Enterprise Architecture (EA has gained importance in recent years, mainly for its concept of “alignment” between the strategic and operational levels of organizations. Such alignment occurs when Information Technology (IT is applied correctly and timely, working in synergy and harmony with strategy and the operation to achieve mutually their own goals and satisfy the organizational needs.Both the strategic and operational levels have standards that help model elements necessary to obtain desired results. In this sense, BMM and BPMN were selected because both have the support of OMG and they are fairly well known for modelling the strategic level and operational level, respectively. In addition, i* modeling goal can be used for reducing the gap between these two standards. This proposal may help both the high-level design of the information system and to the appropriate identification of the business processes that will support it.This paper presents a methodology for aligning strategy and the operation based on standards and heuristics. We have made a classification for elements of the models and, for some specific cases, an extension of the heuristics associated between them. This allows us to propose methodology, which uses above-mentioned standards and combines mappings, transformations and actions to be considered in the alignment process.

  16. [Methodological approaches to the development of environmentally benign technology for the use of solid waste in iron metallurgy].

    Science.gov (United States)

    Pugin, K G; Vaĭsman, Ia I

    2013-01-01

    On the basis of the life cycle of materials, containing wastes of iron and steel industry, new methodological approaches to the assessment of technologies of the secondary use of wastes are developed A complex criteria for selection of the technology for the use of resource potential of solid waste of iron and steel industry are developed with taking into account environmental, technological and economic indices. The technology of the use of wastes of ferrovanadium industry as bulk solid materials at the solid waste landfill is shown.

  17. Bioethanol Production from Raw Juice as Intermediate of Sugar Beet Processing: A Response Surface Methodology Approach

    Directory of Open Access Journals (Sweden)

    Stevan Popov

    2010-01-01

    Full Text Available Response surface methodology (RSM was used for selecting optimal fermentation time and initial sugar mass fraction in cultivation media based on raw juice from sugar beet in order to produce ethanol. Optimal fermentation time and initial sugar mass fraction for ethanol production in batch fermentation by free Saccharomyces cerevisiae cells under anaerobic conditions at the temperature of 30 °C and agitation rate of 200 rpm were estimated to be 38 h and 12.30 % by mass, respectively. For selecting optimal conditions for industrial application, further techno-economic analysis should be performed by using the obtained mathematical representation of the process (second degree polynomial model. The overall fermentation productivity of five different types of yeast was examined and there is no significant statistical difference between them.

  18. Theoretical and methodological approaches to the diagnosis of the region's state material reservation system status

    Directory of Open Access Journals (Sweden)

    Aleksandr Anatol'evich Kuklin

    2011-09-01

    Full Text Available This paper reviews the structural components of the state reserve theory with elements of decomposition and tools for studies in separate directions. The system of state material reserve, which includes the following components: economy - people - natural environment - is a necessary and sufficient reserve for their operation and development which is having the ability to respond to short-, medium- and long-term fluctuations in the economy and consider the risks of adverse factors appliance. It was determined that a necessary and sufficient reserve for the operation and development of the region is a major factor in ensuring its economic security. A method of diagnostics for the state material reserve system within the economic security of the region is presented and described. The approbation of the methodological apparatus for the assessment of the state material reserve by the example on the Ural Federal District was done.

  19. [Nursing care systematization according to the nurses' view: a methodological approach based on grounded theory].

    Science.gov (United States)

    de Medeiros, Ana Lúcia; dos Santos, Sérgio Ribeiro; de Cabral, Rômulo Wanderley Lima

    2012-09-01

    This study was aimed at understanding, from the nurses' perspective, the experience of going through the Systematization of nursing care (SNC) in an obstetric service unit. We used grounded theory as the theoretical and methodological framework. The subjects of this study consisted of thirteen nurses from a public hospital in the city of João Pessoa, in the state of Paraíba. The data analysis resulted in the following phenomenon. "perceiving SNC as a working method that organizes, directs and improves the quality of care by bringing visibility and providing security for the nursing staff" The nurses expressed the extent of knowledge about the SNC experienced in obstetrics as well as considered the nursing process as a decision-making process, which guides the reasoning of nurses in the planning of nursing care in obstetrics. It was concluded that nurses perceive the SNC as an instrument of theoretical-practical articulation leading to personalized assistance.

  20. Optimization Parameters of tool life Model Using the Taguchi Approach and Response Surface Methodology

    Directory of Open Access Journals (Sweden)

    Kompan Chomsamutr

    2012-01-01

    Full Text Available The objective of this research is to compare the cutting parameters of turning operation the work pieces of medium carbon steel (AISI 1045 by finding the longest tool life by Taguchi methods and Response Surface Methodology: RSM. This research is to test the collecting data by Taguchi method. The analyses of the impact among the factors are the depth of cut, cutting speed and feed rate. This research found that the most suitable response value; and tool life methods give the same suitable values, i.e. feed rate at 0.10 mm/rev, cutting speed at 150 m/min, and depth of cut at 0.5 mm, which is the value of longest tool life at 670.170 min, while the average error is by RSM at the percentage of 0.07 as relative to the testing value.

  1. Teaching Theory of Science and Research Methodology to Nursing Students: A Practice-Developing Approach

    DEFF Research Database (Denmark)

    Sievert, Anne; Chaiklin, Seth

    2007-01-01

    , in a principled way, to select subject-matter content for a course for nursing students on theory of science and research methodology. At the same time, the practical organisation of the project was motivated by a practice-developing research perspective. The purpose of the presentation is to illustrate how...... in organising the project (e.g., attention to the motives of the participants, tasks that serve to develop consciousness about general needs, general structure that reflects the whole of the practice – both for teachers and students), together with a discussion of the main characteristics of how the project...... achieved. This specific problem reflects a more general problem for the cultural-historical tradition, namely, how to work with a focus on practice and change of practice from a theoretical perspective....

  2. RESPONSE SURFACE METHODOLOGY APPROACH FOR OPTIMIZATION OF FLAX SEED OIL BLEACHING PROCESS

    Directory of Open Access Journals (Sweden)

    Miroslav Ondrejovič

    2013-10-01

    Full Text Available Flax seed is an important source of omega-3 polyunsaturated fatty acids essential for human physiology. For low oxidation stability, specific taste and concomitant color compounds this oil is poorly applicable as nutraceutical additive. The aim of this study was optimization of flax seed oil bleaching. The optimal conditions for the bleaching process were determined using response surface methodology. A central composite design was used to investigate the effects of three independent variables, namely solid to liquid ratio, temperature and time, to output parameters of the bleaching process such as crude oil color expressed as optical density at 490 nm, acid and peroxide value. Calculated optimal conditions for the bleaching, expressed by the optical density of the oil were as follows: temperature 50°C, bleaching time 77 minutes and solid-liquid ratio 56 g of bleaching agent to 1 liter of oil.

  3. Methodological quality of systematic reviews in subfertility: a comparison of two different approaches.

    Directory of Open Access Journals (Sweden)

    Ivor Popovich

    Full Text Available BACKGROUND: Systematic reviews are used widely to guide health care decisions. Several tools have been created to assess systematic review quality. The measurement tool for assessing the methodological quality of systematic reviews known as the AMSTAR tool applies a yes/no score to eleven relevant domains of review methodology. This tool has been reworked so that each domain is scored based on a four point scale, producing R-AMSTAR. METHODS AND FINDINGS: We aimed to compare the AMSTAR and R-AMSTAR tools in assessing systematic reviews in the field of assisted reproduction for subfertility. All published systematic reviews on assisted reproductive technology, with the latest search for studies taking place from 2007-2011, were considered. Reviews that contained no included studies or considered diagnostic outcomes were excluded. Thirty each of Cochrane and non-Cochrane reviews were randomly selected from a search of relevant databases. Both tools were then applied to all sixty reviews. The results were converted to percentage scores and all reviews graded and ranked based on this. AMSTAR produced a much wider variation in percentage scores and achieved higher inter-rater reliability than R-AMSTAR according to kappa statistics. The average rating for Cochrane reviews was consistent between the two tools (88.3% for R-AMSTAR versus 83.6% for AMSTAR but inconsistent for non-Cochrane reviews (63.9% R-AMSTAR vs. 38.5% AMSTAR. In comparing the rankings generated between the two tools Cochrane reviews changed an average of 4.2 places, compared to 2.9 for non-Cochrane. CONCLUSION: R-AMSTAR provided greater guidance in the assessment of domains and produced quantitative results. However, there were many problems with the construction of its criteria and AMSTAR was much easier to apply consistently. We recommend that AMSTAR incorporates the findings of this study and produces additional guidance for its application in order to improve its reliability and

  4. Basic Approaches to Media Education in Russia. Sociocultural and Methodological Aspects

    Directory of Open Access Journals (Sweden)

    Irina Chelysheva

    2016-12-01

    Full Text Available The articles presents a brief review of basic approaches to media education in Russia from the genesis to present-day conditions of Russian media pedagogy. The historical analysis of media education in Russia has shown that Russian media education tradition relies on several dominant theoretical approaches such as the semiotic, culturological, aesthetic, ethical, sociocultural and critical thinking development conceptions. Contemporary researches focus on studying media culture, various media effects and forms of media addiction, Internet safety and digital competences. Future research prospects of media education in Russia involve further development of scientific media education centers and schools promoting the investigation of urgent theoretical and practical media pedagogy issues.

  5. Identifying Opportunities for Decision Support Systems in Support of Regional Resource Use Planning: An Approach Through Soft Systems Methodology.

    Science.gov (United States)

    Zhu; Dale

    2000-10-01

    / Regional resource use planning relies on key regional stakeholder groups using and having equitable access to appropriate social, economic, and environmental information and assessment tools. Decision support systems (DSS) can improve stakeholder access to such information and analysis tools. Regional resource use planning, however, is a complex process involving multiple issues, multiple assessment criteria, multiple stakeholders, and multiple values. There is a need for an approach to DSS development that can assist in understanding and modeling complex problem situations in regional resource use so that areas where DSSs could provide effective support can be identified, and the user requirements can be well established. This paper presents an approach based on the soft systems methodology for identifying DSS opportunities for regional resource use planning, taking the Central Highlands Region of Queensland, Australia, as a case study.

  6. THE CLUSTER APPROACH TO INNOVATION AND TECHNOLOGICAL DEVELOPMENT OF RUSSIA AND UKRAINE: methodological and organizational issues

    Directory of Open Access Journals (Sweden)

    N. I. Komkov

    2013-01-01

    Full Text Available The methodical and organizational problems of the cluster approach to economic development. Notes a number of important conditions and signs of cluster formation: innovation, competitiveness, voluntary, mutually beneficial participation in the cluster. The problems of the formation of clusters inRussiaandUkraine. The problems of the formation and management of shared clusterRussiaandUkraine

  7. Moving beyond the Deep and Surface Dichotomy; Using Q Methodology to Explore Students' Approaches to Studying

    Science.gov (United States)

    Godor, Brian P.

    2016-01-01

    Student learning approaches research has been built upon the notions of deep and surface learning. Despite its status as part of the educational research canon, the dichotomy of deep/surface has been critiqued as constraining the debate surrounding student learning. Additionally, issues of content validity have been expressed concerning…

  8. TOURIST TRAFFIC BETWEEN MOLDOVA AND ROMANIA: A LOGISTICAL APPROACH (Methodological issues

    Directory of Open Access Journals (Sweden)

    Alexandru GRIBINCEA

    2013-06-01

    Full Text Available The research of the authors constitutes a succinct analysis of the touristic flows between Moldova and Romania during 2005-2012. The analysis is carried out based on a logistical approach, by comparing the physical touristic and cash touristic flows, and specifies the national statistics in the field of tourism.

  9. Assessment of Effectiveness of Use of Intellectual Potential of a University: A Methodological Approach

    Science.gov (United States)

    Stukalova, Irina B.; Stukalova, Anastasia A.; Selyanskaya, Galina N.

    2016-01-01

    This article presents the results of theoretical analysis of existing approaches to the categories of the "intellectual capital" and "intellectual potential" of an organization. The authors identified the specific peculiarities of developing the intellectual potential of a university and propose their own view of its structure.…

  10. [New methodological approach to hygienic audit of learning and upbringing environment for children in educational institutions].

    Science.gov (United States)

    Kuchma, V R; Stepanova, M I; Aleksandrova, I E; Shumkova, T V; Sedova, A S; Zvezdina, I V; Moldovanov, V V; Safonkina, S G

    2014-01-01

    A methodical approach to the hygienic assessment of the educational environment in children's educational institutions was developed and tested for the objective determination of the level ofsanitary and epidemiological welfare and effective planning of preventive measures with bearing in mind environmental factors which have the most negative impact on children's health.

  11. Evaluation and Selection of Indicators for Land Degradation and Desertification Monitoring: Methodological Approach

    NARCIS (Netherlands)

    Kosmas, C.; Karis, O.; Karavitis, C.; Ritsema, C.J.; Salvati, L.; Acikalin, S.; Alcala, S.; Alfama, P.; Atlhopheng, J.; Barrera, J.; Belgacem, A.; Sole-Benet, A.; Brito, J.; Chaker, M.; Chanda, R.; Coelho, C.; Darkoh, M.; Diamantis, I.; Ermolaeva, O.; Fassouli, V.; Fei, W.; Fernandez, F.; Ferreira, A.; Gokceoglu, C.; Gonzalez, D.; Gungor, H.; Hessel, R.; Juying, J.; Khatteli, H.; Kounalaki, A.; Laouina, A.; Lollino, P.; Lopes, M.; Magole, L.; Medina, L.; Mendoza, M.; Morais, P.; Mulale, K.; Ocakoglu, F.; Ouessar, M.; Ovalle, C.; Perez, C.; Perkins, J.; Pliakas, F.; Polemio, M.; Pozo, A.; Prat, C.; Qinke, Y.; Ramos, A.; Riquelme, J.; Romanenkov, V.; Rui, L.; Santaloia, F.; Sebego, R.; Sghaier, M.; Silva, N.; Sizemskaya, M.; Soares, J.; Sonmez, H.; Taamallah, H.; Tezcan, L.; Torri, D.; Ungaro, F.; Valente, S.; Vente, de J.; Zagal, E.; Zeiliguer, A.; Zhonging, W.; Ziogas, A.

    2014-01-01

    An approach to derive relationships for defining land degradation and desertification risk and developing appropriate tools for assessing the effectiveness of the various land management practices using indicators is presented in the present paper. In order to investigate which indicators are most e

  12. Developing and Managing University-Industry Research Collaborations through a Process Methodology/Industrial Sector Approach

    Science.gov (United States)

    Philbin, Simon P.

    2010-01-01

    A management framework has been successfully utilized at Imperial College London in the United Kingdom to improve the process for developing and managing university-industry research collaborations. The framework has been part of a systematic approach to increase the level of research contracts from industrial sources, to strengthen the…

  13. The Methodological Approach to Determining the Level of Formation and Provision of Enterprise Personnel Security

    Directory of Open Access Journals (Sweden)

    Gavkalova Nataliia L.

    2016-11-01

    Full Text Available The aim of the article is to substantiate the methodical approach to determining the level of formation and provision of enterprise personnel security. By analyzing, systematizing and generalizing scientific achievements of many scientists, approaches to the evaluation of personnel security at the enterprise were considered, a set of indices for evaluation of personnel security was defined. There justified the urgency of creating a comprehensive approach to evaluation of personnel security that includes implementation of the following stages: defining a list of indices corresponding to the level of formation and provision of personnel security with the help of the expert evaluation method; calculating integral indices of personnel security for each component and the corresponding level by means of the taxonomic analysis; grouping enterprises by the level of formation and provision of personnel security with the use of the cluster and discriminant analysis. It is found that the implementation of this approach will allow not only determining the level of formation and provision of personnel security at the enterprise, but also developing appropriate recommendations on improving its state. Prospects for further research in this direction are evaluation of conditions for formation and provision of personnel security at the enterprise, which will enable revealing negative destabilizing factors that influence personnel security

  14. Teaching Methodologies for Population Education: Inquiry/Discovery Approach, Values Clarification.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.

    Divided into two sections, this booklet demonstrates how the discovery/inquiry approach and values clarification can be used to teach population education. Each part presents a theoretical discussion of a teaching method including its definition, its relevance to population education, some outstanding characteristics that make it suitable for…

  15. Transnational Social Movements and the Globalization Agenda: A methodological Approach Based oh the Analysis of the World Social Forum

    Directory of Open Access Journals (Sweden)

    Carlos Milani

    2016-09-01

    Full Text Available Globalization is not merely a competition for market shares and well-timed economic growth initiatives; neither is it just a matter of trade opportunities and liberalization. It has also evolved into a social and political struggle for imposing cultural values and individual preferences. Based on this broader context, this paper adopts the following assumption: transnational networks of social movements are the expression of a new social subject and have shifted their scale of political intervention since the 1990s in order to make their fight for social justice a politically pertinent action. Global social justice has become the motto of transnational social movements in world politics, where political decisions no longer rely exclusively on nation-states. In pursuance of developing this assumption, this paper approaches the discussion in two general parts: firstly, it presents a theoretical and methodological approach for analysing transnational social movements; secondly, it looks into the World Social Forum as one of their key political expressions.Globalization is not merely a competition for market shares and well-timed economic growth initiatives; neither is it just a matter of trade opportunities and liberalization. It has also evolved into a social and political struggle for imposing cultural values and individual preferences. Based on this broader context, this paperadopts the following assumption: transnational networks of social movements are the expression of a new social subject and have shifted their scale of political intervention since the 1990s in order to make their fight for social justice a politically pertinent action. Global social justice has become the motto of transnational social movements in world politics, where political decisions no longer rely exclusively on nation-states. In pursuance of developing this assumption, this paper approaches the discussion in two general parts: firstly, it presents a theoretical and

  16. Political Ecology Approach to Island Tourism Planning and Climate Change Adaptation: A Methodological Exploration

    Directory of Open Access Journals (Sweden)

    Virgilio Maguigad

    2015-12-01

    Full Text Available Climate change is emerging as the main driver of current and future climate-related risks for small islands. These risks include sea level rise, stronger tropical cyclones, and changing rainfall patterns. While there is now high confidence in the scientific community that the present change in climate is anthropogenic in nature compared to the Earth’s geologic history of natural variability, there is a need for more detailed evaluations of the relationships between humans and the climate. As a human activity affected by climate change, tourism is in need of such analyses since current positivist analytical tools are inadequate for evaluating the complexity of such interactions. This paper reviews the literature, scientific frameworks, and methodological epistemologies used to analyse human community relationships to natural environments and their applicability in small island tourism environments that are impacted by climate change in the Philippines. Political ecology emerges as a potent and appropriate framework since climate change adaptation planning processes for island tourism are inherently political. The paper advances the use of political ecology for climate change adaptation to grapple with the equally complex phenomena of island tourism urbanisation and climate change, thereby contributing to the discourse in three research areas.

  17. INNOVATIVE APPROACHES TO RESEARCH METHODOLOGY OF SOCIAL RESPONSIBILITY IN THE FIELD OF RISK MANAGEMENT

    Directory of Open Access Journals (Sweden)

    L. Volokhova

    2016-06-01

    Full Text Available The paper defines the role of insurance and risk management in corporate social responsibility. Analysed some of the social problems of certain sectors of the economy and the distribution of investments by insurance companies in a socially-oriented areas of the economy. The result of the analysis show that the problem of insurance and risk management should be directed to the development of innovative insurance products that would receive specific corporate social value by real locating investments. To better study on strategic risk - management must diversify and improve the traditionally accepted methodological tools. We consider the theory of positional feedback and corresponding IRT innovative model for analysis of complex, highly-defined characteristics of this sector. In order to determine a common objective evaluation system of corporate social responsibility for all companies emphasis on practical social benefits as measuring the effectiveness and success of socially responsible activities, the benefits that the company will receive from the decision of the social project. The proposed comprehensive system of indicators based insurance, which allows you to deepen the study of social responsibility in risk management strategies. The indicator system includes the following sections: 1. Navkolyshnye environment. 2. Local government (social security community. 3. Occupational Safety. 4. Internal corporate relations. 5. Equality. 6. Product Attributes. 7. Management. 8. The interest of business. 9. Liability business. 10. Socially responsible insurance. The comparative characteristic of the efficacy of social activity of companies and assess their socio-oriented activities for the previous ten years.

  18. Rocket Engine Nozzle Side Load Transient Analysis Methodology: A Practical Approach

    Science.gov (United States)

    Shi, John J.

    2005-01-01

    At the sea level, a phenomenon common with all rocket engines, especially for a highly over-expanded nozzle, during ignition and shutdown is that of flow separation as the plume fills and empties the nozzle, Since the flow will be separated randomly. it will generate side loads, i.e. non-axial forces. Since rocket engines are designed to produce axial thrust to power the vehicles, it is not desirable to be excited by non-axial input forcing functions, In the past, several engine failures were attributed to side loads. During the development stage, in order to design/size the rocket engine components and to reduce the risks, the local dynamic environments as well as dynamic interface loads have to be defined. The methodology developed here is the way to determine the peak loads and shock environments for new engine components. In the past it is not feasible to predict the shock environments, e.g. shock response spectra, from one engine to the other, because it is not scaleable. Therefore, the problem has been resolved and the shock environments can be defined in the early stage of new engine development. Additional information is included in the original extended abstract.

  19. Selection Methodology Approach to Preferable and Alternative Sites for the First NPP Project in Yemen

    Energy Technology Data Exchange (ETDEWEB)

    Kassim, Moath [Kyunghe Univ., Yongin (Korea, Republic of); Kessel, David S. [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-05-15

    The purpose of this paper is to briefly present the methodology and results of the first siting study for the first nuclear power plant (NPP) in Yemen. In this study it has been demonstrated that there are suitable sites for specific unit/units power of 1000 MWt (about 300 MWe) nuclear power plant. To perform the site selection, a systematic selection method was developed. The method uses site-specific data gathered by literature review and expert judgement to identify the most important site selection criteria. A two-step site selection process was used. Candidate sites were chosen that meet a subset of the selection criteria that form the most important system constraints. These candidate sites were then evaluated against the full set of selection criteria using the Analytical Hierarchy Process Method (AHP). Candidate sites underwent a set of more specific siting criteria weighted by expert judgment to select preferable sites and alternatives using AHP method again. Expert Judgment method was used to rank and weight the importance of each criteria, then AHP method used to evaluate and weight the relation between criterion to criterion and between all criteria against the global weight. Then logical decision software was used to rank sites upon their weighting value.

  20. Health related war dioxin in Vietnam today, methodological approach in evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Thom, Le Hong; Tran, Manh Hung; Phung, Tri Dung [Ministry of Health, Ha Noi (Viet Nam)

    2004-09-15

    The Chemical war, that lasted for more than 10 years (1961-1971) had ended 30 years ago, but its severe outcomes on exposed human health seem to be far from ending. By the newest calculations, there should be more than 80 million of herbicides, including no less than 500 kg of Dioxin - 2,3,7,8-TCDD have been sprayed over land of South Vietnam. Dioxin the most ecotoxic agent, that human knowns to now, and have been researched by many scientists over the world. The studies conducted in experimental animals and partly in human tissues, have demonstrated, that dioxin cause the toxicity for many biofunctions, especially for systems like: nervous, digestive, immunoresponses, reproductive health, skin disorders, and carcinogenicity. It seems to be, that Viet nam have become a ''biggest laboratory'' of dioxin testing and its effects studying over the world. Many research into human health have been done, but the opinions of health outcomes, related to dioxin exposure still cause the debates. A lot of studies conducted on nature and man in Viet nam also, unfortunately there is not yet the overview general, concerning the methodological as epidemiological criteria. This report sum up the health, especially the reproductive outcomes, based strictly on the epidemiological disciplines.

  1. External Validity and Model Validity: A Conceptual Approach for Systematic Review Methodology

    Directory of Open Access Journals (Sweden)

    Raheleh Khorsan

    2014-01-01

    Full Text Available Background. Evidence rankings do not consider equally internal (IV, external (EV, and model validity (MV for clinical studies including complementary and alternative medicine/integrative health care (CAM/IHC research. This paper describe this model and offers an EV assessment tool (EVAT© for weighing studies according to EV and MV in addition to IV. Methods. An abbreviated systematic review methodology was employed to search, assemble, and evaluate the literature that has been published on EV/MV criteria. Standard databases were searched for keywords relating to EV, MV, and bias-scoring from inception to Jan 2013. Tools identified and concepts described were pooled to assemble a robust tool for evaluating these quality criteria. Results. This study assembled a streamlined, objective tool to incorporate for the evaluation of quality of EV/MV research that is more sensitive to CAM/IHC research. Conclusion. Improved reporting on EV can help produce and provide information that will help guide policy makers, public health researchers, and other scientists in their selection, development, and improvement in their research-tested intervention. Overall, clinical studies with high EV have the potential to provide the most useful information about “real-world” consequences of health interventions. It is hoped that this novel tool which considers IV, EV, and MV on equal footing will better guide clinical decision making.

  2. A reliable methodology for monitoring unstable slopes: the multi-platform and multi-sensor approach

    Science.gov (United States)

    Castagnetti, Cristina; Bertacchini, Eleonora; Corsini, Alessandro; Rivola, Riccardo

    2014-10-01

    High resolution topography, by involving Digital Terrain Models (DTMs) and further accurate techniques for a proper displacement identification, is a valuable tool for a good and reliable description of unstable slopes. By comparing multitemporal surveys, the geomorphology of a landslide may be analyzed as well as the changes over time, the volumes transportation and the boundaries evolution. Being aware that a single technique is not sufficient to perform a reliable and accurate survey, this paper discusses the use of multi-platform, multi-source and multi-scale observations (both in terms of spatial scale and time scale) for the study and monitoring of unstable slopes. The final purpose is to highlight and validate a methodology based on multiple sensors and data integration, useful to obtain a comprehensive GIS (Geographic Information System) which can successfully be used to manage natural disasters or to improve the knowledge of a specific phenomenon in order to prevent and mitigate the hydro-geological risk. The novelty of the present research lies in the spatial integration of multiple remote sensing techniques such as: integration of Airborne Laser Scanning (ALS) and Terrestrial Laser Scanning (TLS) to provide a comprehensive and accurate surface description (DTM) at a fixed epoch (spatial continuity); continuous monitoring by means of spatial integration of Automated Total Station (ATS) and GNSS (Global Navigation Satellite System) to provide accurate surface displacement identification (time continuity). Discussion makes reference to a rockslide located in the northern Apennines of Italy from 2010 to 2013.

  3. Sustainability of green jobs in Portugal: a methodological approach using occupational health indicators.

    Science.gov (United States)

    Moreira, Sandra; Vasconcelos, Lia; Silva Santos, Carlos

    2017-08-08

    This study aimed to develop a methodological tool to analyze and monitor the green jobs in the context of Occupational Health and Safety. A literature review in combination with an investigation of Occupational Health Indicators was performed. The resulting tool of Occupational Health Indicators was based on the existing information of "Single Report" and was validated by national's experts. The tool brings together 40 Occupational Health Indicators in four key fields established by World Health Organization in their conceptual framework "Health indicators of sustainable jobs." The tool proposed allows for assessing if the green jobs enabled to follow the principles and requirements of Occupational Health Indicators and if these jobs are as good for the environment as for the workers' health, so if they can be considered quality jobs. This shows that Occupational Health Indicators are indispensable for the assessment of the sustainability of green jobs and should be taken into account in the definition and evaluation of policies and strategies of the sustainable development.

  4. Ethical concerns as a methodological proposal to approach cross-cutting themes.

    Directory of Open Access Journals (Sweden)

    Sansao Albino Timbane

    2015-12-01

    Full Text Available The present study highlight how the investment in ethical concerns can contribute as a learning shuttle in a virtual ambient directed to the learning, more than to the teaching. Face-to-face meetings, in a classroom, and distance meetings, on Forchat online space were made. The students proactively participated on the discussions with freedom to decide about the paper’s assumption and thematic propositions according to the personal interest on the studies topics, sometimes as a moderator, other times as contributor, without the teacher interference.  The reality problematization through the ethical concerns presented as relevant effect the proactively engagement on the discussions about the proposed topics, with gains to the conceptual construction and to the methodological positions in the research.  Instigated by the challenge of cross-cutting themes discussed, on a virtual learning ambient, themes related with: docent practice, learning, professional formation, evaluation, theory- practice relation, refreshing debates and reflections about ethical concerns, making a collective text which at same time respected the individual contributions heterogeneity and the produced senses.

  5. An intelligent approach to the discovery of luminescent materials using a combinatorial approach combined with Taguchi methodology.

    Science.gov (United States)

    Chen, Lei; Chu, Cheng-I; Chen, Kuo-Ju; Chen, Po-Yuan; Hu, Shu-Fen; Liu, Ru-Shi

    2011-01-01

    A significant advance made in combinatorial approach research was that the emphasis shifted from simple mixing to intelligent screening, so as to improve the efficiency and accuracy of discovering new materials from a larger number of diverse compositions. In this study, the long-lasting luminescence of SrAl(2)O(4), which is co-doped with Eu(2+), Ce(3+), Dy(3+), Li(+) and H(3)BO(3), was investigated based on a combinatorial approach in conjunction with the Taguchi method. The minimal number of 16 samples to be tested (five dopants and four levels of concentration) were designed using the Taguchi method. The samples to be screened were synthesized using a parallel combinatorial strategy based on ink-jetting of precursors into an array of micro-reactor wells. The relative brightness of luminescence of the different phosphors over a particular period was assessed. Ce(3+) was identified as the constituent that detrimentally affected long-lasting luminescence. Its concentration was optimized to zero. Li(+) had a minor effect on long-lasting luminescence but the main factors that contributed to the objective property (long-lasting luminescence) were Eu(2+), Dy(3+) and H(3)BO(3), and the concentrations of these dopants were optimized to 0.020, 0.030 and 0.300, respectively, for co-doping into SrAl(2)O(4). This study demonstrates that the utility of the combinatorial approach for evaluating the effect of components on an objective property (e.g. phosphorescence) and estimating the expected performance under the optimal conditions can be improved by the Taguchi method.

  6. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect

    DEFF Research Database (Denmark)

    Triantafyllou, Evangelia; Kofoed, Lise; Purwins, Hendrik

    2016-01-01

    One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class...... through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM) are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens......, tools and resources used in specific flipped classroom models, and it can make educators more aware of the decisions that have to be taken and people who have to be involved when designing a flipped classroom. By using the LD-CM, this paper also draws attention to the importance of characteristics...

  7. Methodological approaches to evaluate teratogenic risk using birth defect registries: advantages and disadvantages.

    Science.gov (United States)

    Poletta, Fernando A; López Camelo, Jorge S; Gili, Juan A; Leoncini, Emmanuele; Castilla, Eduardo E; Mastroiacovo, Pierpaolo

    2012-01-01

    Different approaches have been used in case-control studies to estimate maternal exposure to medications and the risk of birth defects. However, the performance of these approaches and how they affect the odds ratio (OR) estimates have not been evaluated using birth-defect surveillance programmes. The aim of this study was to evaluate the scope and limitations of three case-control approaches to assess the teratogenic risk of birth defects in mothers exposed to antiepileptic medications, insulin, or acetaminophen. We studied 110,814 non-malformed newborns and 58,514 live newborns with birth defects registered by the Latin American Collaborative Study of Congenital Anomalies (ECLAMC) between 1967 and 2008. Four controls were randomly selected for each case in the same hospital and period, and three different control groups were used: non-malformed newborns (HEALTHY), malformed newborns (SICK), and a subgroup of SICK, only-exposed cases (OECA). Associations were evaluated using OR and Pearson's chi-square (Pcontrols. SICK and OECA odds ratios cannot be considered a direct estimate of the true population OR except under certain conditions. However, the SICK and OECA designs could provide practical information to generate hypotheses about potential teratogens.

  8. A multiobjective discrete stochastic optimization approach to shared aquifer management: Methodology and application

    Science.gov (United States)

    Siegfried, Tobias; Kinzelbach, Wolfgang

    2006-02-01

    Negative effects from groundwater mining are observed globally. They threaten future supply locally. Especially in semiarid to arid regions, where aquifers are the sole freshwater resource, this is problematic and can lead to an excessive rise of provision costs. Proper resource management in such environments is crucial. In many instances, however, aquifers are common property resources. In such cases and depending on resource characteristics and the nature of competing uses, their management is inherently multiobjective, and benefits from cooperative management are likely to be substantial. This paper presents a methodology for the determination of optimal, cooperative allocation policies in multiobjective aquifer management problems. Our model couples a finite difference aquifer model with an economic model that accounts for water provision costs. Discounted temporal installation and pumping and conveyance costs determine the vector-valued objective function. Each of the objectives characterizes the individual present costs over a given time horizon that the corresponding decision makers wish to minimize. Constraint handling is implemented by the option of moving wells. A multiobjective evolutionary algorithm is coupled to the management model so as to approximate cooperative tradeoff policies on the Pareto surface. These solutions can be ranked against existing, noncooperative status quo strategies. Consequently, the simulation-optimization model is applied to the northwest Sahara aquifer system which is used noncooperatively as a resource by Algeria, Tunisia, and Libya. We find that significant capital gains can be achieved by the establishment of intelligent pump scheduling. Since each country could benefit, a strong incentive toward the implementation of such cooperative strategies exists.

  9. Methodologically sound: Evaluating the psychometric approach to the assessment of human life history [reply to Copping, Campbell, and Muncer, 2014].

    Science.gov (United States)

    Figueredo, Aurelio José; Cabeza de Baca, Tomás; Black, Candace Jasmine; García, Rafael Antonio; Fernandes, Heitor Barcellos Ferreira; Wolf, Pedro Sofio Abril; Woodley of Menie, Michael Anthony

    2015-04-06

    Copping, Campbell, and Muncer (2014) have recently published an article critical of the psychometric approach to the assessment of life history (LH) strategy. Their purported goal was testing for the convergent validation and examining the psychometric structure of the High-K Strategy Scale (HKSS). As much of the literature on the psychometrics of human LH during the past decade or so has emanated from our research laboratory and those of close collaborators, we have prepared this detailed response. Our response is organized into four main sections: (1) A review of psychometric methods for the assessment of human LH strategy, expounding upon the essence of our approach; (2) our theoretical/conceptual concerns regarding the critique, addressing the broader issues raised by the critique regarding the latent and hierarchical structure of LH strategy; (3) our statistical/methodological concerns regarding the critique, examining the validity and persuasiveness of the empirical case made specifically against the HKSS; and (4) our recommendations for future research that we think might be helpful in closing the gap between the psychometric and biometric approaches to measurement in this area. Clearly stating our theoretical positions, describing our existing body of work, and acknowledging their limitations should assist future researchers in planning and implementing more informed and prudent empirical research that will synthesize the psychometric approach to the assessment of LH strategy with complementary methods.

  10. Methodologically Sound: Evaluating the Psychometric Approach to the Assessment of Human Life History [Reply to Copping, Campbell, and Muncer, 2014

    Directory of Open Access Journals (Sweden)

    Aurelio José Figueredo

    2015-04-01

    Full Text Available Copping, Campbell, and Muncer (2014 have recently published an article critical of the psychometric approach to the assessment of life history (LH strategy. Their purported goal was testing for the convergent validation and examining the psychometric structure of the High-K Strategy Scale (HKSS. As much of the literature on the psychometrics of human LH during the past decade or so has emanated from our research laboratory and those of close collaborators, we have prepared this detailed response. Our response is organized into four main sections: (1 A review of psychometric methods for the assessment of human LH strategy, expounding upon the essence of our approach; (2 our theoretical/conceptual concerns regarding the critique, addressing the broader issues raised by the critique regarding the latent and hierarchical structure of LH strategy; (3 our statistical/methodological concerns regarding the critique, examining the validity and persuasiveness of the empirical case made specifically against the HKSS; and (4 our recommendations for future research that we think might be helpful in closing the gap between the psychometric and biometric approaches to measurement in this area. Clearly stating our theoretical positions, describing our existing body of work, and acknowledging their limitations should assist future researchers in planning and implementing more informed and prudent empirical research that will synthesize the psychometric approach to the assessment of LH strategy with complementary methods.

  11. Methodological approach for the assessment, protection, promotion and management of geoheritage

    Science.gov (United States)

    Reynard, E.; Perret, A.; Grangier, L.; Kozlik, L.

    2012-04-01

    During the last decade, within the framework of the Working group on geomorphosites of the International Association of Geomorphologists (IAG), a set of methods for the assessment of geomorphological heritage have been developed. All are based on assessment criteria, more or less quantitative, sometimes grouped in generic categories (intrinsic values, additional values, use values, etc.) (see Reynard, 2009 for a review). Most of these methods may be used with numeric scores, allowing the "calculation" of a site's value and the classification of geomorphosites according to their values. More recently, methodological improvements have been made in other domains of geomorphosite studies, such as cartography, the education to geoheritage, the evaluation of public needs, and the evaluation of geotourist products. The analytical framework we propose here aims at covering all the stages of what we could name "the integrative management of geomorphosites", from the selection of important sites to the evaluation of geotourist and educational activities by the users. The work is divided into two phases: assessment; and management. The first phase is divided in two stages: the selection of potential geomorphosites; and the assessment of these sites by using a specific method developed in Lausanne (Reynard et al., 2007). The management phase is also divided in two stages: the elaboration of a management strategy (with the creation of geotourist and educational products and the elaboration of a conservation strategy); and the evaluation of the scientific work by the users. The proposed analytical framework is tested in the Hérens Valley (Switzerland). The valley ranges from 500 m to 4357 m ASL and is rich in terms of mountain landforms (periglacial and glacial landforms, gravitational deposits, fluvial and torrential landforms). It is representative for landscape reconstructions since the end of the Last Glacial Maximum (LGM). The valley has also a rich ecological and cultural

  12. Alternative theoretical and methodological approaches for exploring higher education in Art and Crafts

    Directory of Open Access Journals (Sweden)

    Marte Sørebø Gulliksen

    2009-12-01

    Full Text Available This article presents and discusses approaches for exploring higher education in Art and Crafts. The concepts exploring versus research and the different foci in an insider perspective versus an outsider perspective introduces the theme. An insider perspective is said to be a useful starting point for inquiry, referring to Frayling’s trichotomy research into, research on and research through from 1993. The field of higher education in Art and Crafts education is shortly presented as comprising two main areas of knowledge: knowledge of education, and knowledge about the different subject areas within Art and Crafts. Both theory and practice are a part of these areas of knowledge. As higher education in Art and Crafts is a making profession, the most prominent challenge when exploring this today is thus said to be to develop research based knowledge on Education in Art and Crafts as a making discipline.  Two keywords are deemed to be useful in approaching this theme: Mode 2 knowledge production and transdisciplinarity. The article concludes with describing specific ways of doing this today from within the context of application. Two examples of large research projects in Scandinavia are presented as examples of such projects.

  13. New approach for the determination of aerosol refractive indices - Part I: Theoretical bases and numerical methodology

    Science.gov (United States)

    Herbin, H.; Pujol, O.; Hubert, P.; Petitprez, D.

    2017-10-01

    The knowledge of aerosol complex refractive indices on wide spectral range with high spectral resolution is important for many research fields and applications. Various combinations of experimental/theoretical/numerical approaches have been employed to determine the optical indices of aerosol particles. However, each approach has its own advantages and limitations that restrict its generalization. This article is first part of a work aimed at proposing a new technique for determining the optical constants of aerosols. Experimentally, the method is based on recording transmittance spectra of an aerosol flow from thermal infrared to UV-visible combined with the size distribution measurements. Herein, we present the theoretical and numerical bases of the algorithm developed to retrieve the imaginary and real parts of refractive indices. This model associates the Mie theory, the single subtractive Kramers-Kronig relations, and the optimal estimation method with an iterative process. In order to quantify the capabilities of the algorithm to retrieve complex refractive indices, inverse calculations are performed from simulated extinction spectra of Quartz particles whose some of optical properties are available in the literature. We have detailed each step of the procedure and performed some comparisons with the most currently employed methods. The impact of experimental accuracy and numerical simulation are investigated in terms of errors, and uncertainties on the retrieved real and imaginary parts of the complex optical index.

  14. Documenting Pornography Use in America: A Comparative Analysis of Methodological Approaches.

    Science.gov (United States)

    Regnerus, Mark; Gordon, David; Price, Joseph

    2016-09-01

    Estimates of pornography use in the United States range widely. We explore the reasons for the variation in such estimates among U.S. adults using data from four different recent nationally representative samples-each of which asked a different type of question about pornography use. We attribute the notable variation in estimates to differences in question wording and answer options, and assert that a survey question asking respondents about their most recent use of pornography minimizes recall bias and is better poised to assess the overall prevalence of pornography in a population than is the more common approach of asking respondents about their historical general-use pattern. When we privileged the most-recent-use approach, survey data from 2014 reveal that 46% of men and 16% of women between the ages of 18 and 39 intentionally viewed pornography in a given week. These numbers are notably higher than most previous population estimates employing different types of questions. The results have ramifications for methods of surveying sensitive self-reported behaviors and for contextualizing scholars' claims as well as popular conversations about the reach and implications of pornography use in the United States.

  15. The transformed-stationary approach: a generic and simplified methodology for non-stationary extreme value analysis

    Science.gov (United States)

    Mentaschi, Lorenzo; Vousdoukas, Michalis; Voukouvalas, Evangelos; Sartini, Ludovica; Feyen, Luc; Besio, Giovanni; Alfieri, Lorenzo

    2016-09-01

    Statistical approaches to study extreme events require, by definition, long time series of data. In many scientific disciplines, these series are often subject to variations at different temporal scales that affect the frequency and intensity of their extremes. Therefore, the assumption of stationarity is violated and alternative methods to conventional stationary extreme value analysis (EVA) must be adopted. Using the example of environmental variables subject to climate change, in this study we introduce the transformed-stationary (TS) methodology for non-stationary EVA. This approach consists of (i) transforming a non-stationary time series into a stationary one, to which the stationary EVA theory can be applied, and (ii) reverse transforming the result into a non-stationary extreme value distribution. As a transformation, we propose and discuss a simple time-varying normalization of the signal and show that it enables a comprehensive formulation of non-stationary generalized extreme value (GEV) and generalized Pareto distribution (GPD) models with a constant shape parameter. A validation of the methodology is carried out on time series of significant wave height, residual water level, and river discharge, which show varying degrees of long-term and seasonal variability. The results from the proposed approach are comparable with the results from (a) a stationary EVA on quasi-stationary slices of non-stationary series and (b) the established method for non-stationary EVA. However, the proposed technique comes with advantages in both cases. For example, in contrast to (a), the proposed technique uses the whole time horizon of the series for the estimation of the extremes, allowing for a more accurate estimation of large return levels. Furthermore, with respect to (b), it decouples the detection of non-stationary patterns from the fitting of the extreme value distribution. As a result, the steps of the analysis are simplified and intermediate diagnostics are

  16. Qualitative inquiry of incivilities at secondary school. Methodological reflections from interactionist approaches

    Directory of Open Access Journals (Sweden)

    Guido García Bastán

    2016-06-01

    Full Text Available The concept of incivilities appeared in the field of studies concerning school violence and conflict within an active search of the social sciences for conceptual lines capable of including types of violence that differ from the physical one. In Argentina some researches, from both qualitative and quantitative designs, have recovered the concept. However its use has been controversial in some ways. In this paper I propose one potential use of the concept for qualitative inquiry. To do so I will present two ‘critical incidents’ to the everyday dinamics of two schools and will analyze them taking into accont contributions from Erving Goffman’s dramaturgical approach and other interactionist traditions. I will also warn about the risk implied in a careless use of the concept: specifically what has been denominated as mechanical transcription of the native speech (Noel, 2009

  17. The cost of reducing CO2 emissions - methodological approach, illustrated by the Danish energy plan

    DEFF Research Database (Denmark)

    Morthorst, P.E.

    1998-01-01

    available. One of the tools available for this purpose is the construction of cost-reduction curves, relating the marginal cost of CO2 reduction and the quantity of the reduced emission to specific technology options. This paper outlines different approaches for establishing cost-reduction curves for CO2...... those technological options that have the highest reduction potential and the lowest marginal costs, and vice versa. Based on the case of the Danish energy plan, the results of the analyses show that a number of reduction options with significant reduction potentials are available at relatively low...... marginal costs. Among others can be mentioned increased use of combined heat and power (CHP), substituting conventional coal-fired CHP plants with biomass ones and the development of offshore wind turbines: (C) 1998 Elsevier Science Ltd. All rights reserved....

  18. A Bayesian approach to the semi-analytic model of galaxy formation: methodology

    CERN Document Server

    Lu, Yu; Weinberg, Martin D; Katz, Neal S

    2010-01-01

    We believe that a wide range of physical processes conspire to shape the observed galaxy population but we remain unsure of their detailed interactions. The semi-analytic model (SAM) of galaxy formation uses multi-dimensional parameterizations of the physical processes of galaxy formation and provides a tool to constrain these underlying physical interactions. Because of the high dimensionality, the parametric problem of galaxy formation may be profitably tackled with a Bayesian-inference based approach, which allows one to constrain theory with data in a statistically rigorous way. In this paper, we develop a generalized SAM using the framework of Bayesian inference. We show that, with a parallel implementation of an advanced Markov-Chain Monte-Carlo algorithm, it is now possible to rigorously sample the posterior distribution of the high-dimensional parameter space of typical SAMs. As an example, we characterize galaxy formation in the current $\\Lambda$CDM cosmology using stellar mass function of galaxies a...

  19. Beyond Description in Interpersonal Construct Validation: Methodological Advances in the Circumplex Structural Summary Approach.

    Science.gov (United States)

    Zimmermann, Johannes; Wright, Aidan G C

    2017-01-01

    The interpersonal circumplex is a well-established structural model that organizes interpersonal functioning within the two-dimensional space marked by dominance and affiliation. The structural summary method (SSM) was developed to evaluate the interpersonal nature of other constructs and measures outside the interpersonal circumplex. To date, this method has been primarily descriptive, providing no way to draw inferences when comparing SSM parameters across constructs or groups. We describe a newly developed resampling-based method for deriving confidence intervals, which allows for SSM parameter comparisons. In a series of five studies, we evaluated the accuracy of the approach across a wide range of possible sample sizes and parameter values, and demonstrated its utility for posing theoretical questions on the interpersonal nature of relevant constructs (e.g., personality disorders) using real-world data. As a result, the SSM is strengthened for its intended purpose of construct evaluation and theory building.

  20. Assessment of functional preparedness of athletes specializing in the sprint, using new methodological approaches

    Directory of Open Access Journals (Sweden)

    Nikolai Malikov

    2016-04-01

    Full Text Available Purpose: study the character of the changes the level of functional preparedness of sportsmen in the autumn-winter preparatory period training cycle of one year. Material & Methods: in the study to take part ten of athletes specializing in the sprint at the age of 19–23 years, and which have sports rank master of Sport and international master of sports. Methods: analysis scientific and methodical literature, pedagogical supervision, pedagogical experiment, methods for assessing functional training using computer technology, methods of mathematical statistics. Results: is defined integrated quantitative value of the level functional of preparedness and her individual components using new methodical approaches. Conclusions: it is shown that the conduct of the optimization functional of preparedness athletes is an important factor in enhancing the effectiveness of the training process.

  1. Accustics and music: a methodological approach to explore sounds emitted by sound pipes

    OpenAIRE

    Coelho, Suzana Maria; PUCRS; Machado, Gisele Ramires; Licencianda da Faculdade de Física, PUCRS

    2015-01-01

    The present article describes a workshop with Physics students, in which the assembly of a mobile was proposed, by using sound pipes to pursue sound  characterization  and  an  approach  to  the  Physic s principles involved in acoustic phenomena. The comparison between the sounds emitted  by  the  mobile  and  musical  instruments  was  possible through aural  perception  exercises.  Besides,  measurements  were  carried  out using virtual and digital tuners; such results have been compared ...

  2. A methodology proposal for collaborative business process elaboration using a model-driven approach

    Science.gov (United States)

    Mu, Wenxin; Bénaben, Frédérick; Pingaud, Hervé

    2015-05-01

    Business process management (BPM) principles are commonly used to improve processes within an organisation. But they can equally be applied to supporting the design of an Information System (IS). In a collaborative situation involving several partners, this type of BPM approach may be useful to support the design of a Mediation Information System (MIS), which would ensure interoperability between the partners' ISs (which are assumed to be service oriented). To achieve this objective, the first main task is to build a collaborative business process cartography. The aim of this article is to present a method for bringing together collaborative information and elaborating collaborative business processes from the information gathered (by using a collaborative situation framework, an organisational model, an informational model, a functional model and a metamodel and by using model transformation rules).

  3. Methodologies of health impact assessment as part of an integrated approach to reduce effects of air pollution

    Energy Technology Data Exchange (ETDEWEB)

    Aunan, K.; Seip, H.M.

    1995-12-01

    Quantification of average frequencies of health effects on a population level is an essential part of an integrated assessment of pollution effects. Epidemiological studies seem to provide the best basis for such estimates. This paper gives an introduction to a methodology for health impact assessment and also the results from selected parts of a case study in Hungary. This case study is aimed at testing and improving the methodology for integrated assessment and focuses on energy production and consumption and implications for air pollution. Using monitoring data from Budapest, the paper gives estimates of excess frequencies of respiratory illness, mortality and other health end-points. For a number of health end-points, particles probably may serve as a good indicator component. Stochastic simulation is used to illustrate the uncertainties imbedded in the exposure-response function applied. The paper uses the ``bottom up approach`` to find cost-effective abatement strategies against pollution damages, where specific abatement measures such as emission standards for vehicles are explored in detail. It is concluded that in spite of large uncertainties in every step of the analysis, an integrated assessment of costs and benefits of different abatement measures is valuable as it clarifies the main objectives of an abatement policy and explicitly describes the adverse impacts of different activities and their relative importance. 46 refs., 11 figs., 2 tabs.

  4. A multidisciplinary methodological approach for slope stability assessment of an area prone to shallow landslides

    Science.gov (United States)

    Bordoni, Massimiliano; Meisina, Claudia; Valentino, Roberto; Bittelli, Marco; Battista Bischetti, Gian; Vercesi, Alberto; Chersich, Silvia; Giuseppina Persichillo, Maria

    2016-04-01

    Rainfall-induced shallow landslides are widespread slope instabilities phenomena in several hilly and mountainous contexts all over the world. Due to their high density of diffusion also in small areas, they can provoke important damages to terrains, infrastructures, buildings, and, sometimes, loss of human lives. Shallow landslides affect superficial soils of limited thickness (generally lower than 2 m), located above weathered or not bedrock levels. Their triggering mechanism is strictly linked to the hydrological response of the soils to rainfall events. Thus, it becomes fundamental a comprehensive analysis of the soil properties which can influence the susceptibility of a slope to shallow landslides. In this study, a multidisciplinary approach was followed for the characterization of the soils and the individuation of the triggering conditions in an area particularly prone to shallow failures, for slope stability assessment. This area corresponded to the hilly sector of North-Eastern Oltrepò Pavese (Lombardy Region, Northern Italy), where the density of shallow landslides is really high, reaching more than 36 landslides per km2. The soils of the study area were analyzed through a multidisciplinary characterization, which took into account for the main geotechnical, mechanical and mineralogical parameters and also for the main pedological features of the materials. This approach allowed for identifying the main features and the horizons which could influence the soil behavior in relation to the conditions that are preparatory to shallow landslides development. In a test-site slope, representative of the main geomorphological, geological and landslides distribution characteristics typical of the study area, a continuous in time monitoring of meteorological (rainfall amount, air temperature, air humidity, atmospheric pressure, net solar radiation, wind speed and direction) and hydrological (soil water content, pore water pressure) parameters was implemented. In

  5. Procedural conflict of appointment and production of Forensic building-technical expertise (FBTE and methodological approaches for their resolution

    Directory of Open Access Journals (Sweden)

    Kolobova Svetlana

    2017-01-01

    Full Text Available This paper analyzes the procedural conflicts arising from the appointment and manufacture of forensic building-technical expertise and methodical recommendations for their resolution. Inconsistencies in some provisions of current legislation governinjudicial activities: the concept of forensic expertise, the legal status of forensic expert, the name of the types of forensic expertise, the legal classification of judicial expertise can lead to the wrong judicial conclusions and judicial errors. The methodological approaches for legislative consolidation of the definition of activities; changes in the civil procedural code, arbitration procedural code, code on administrative offences, Federal law on state expert activity related to the unification of forensic-expert terminology and inclusion in the legal framework of new concepts concerning expert activities. It is proposed to amend the administrative procedure law regarding the timing of execution of forensic building-technical expertise аnd revision sanctions in case of untimely performance of building-technical expertise.

  6. Numerical methodologies for investigation of moderate-velocity flow using a hybrid computational fluid dynamics - molecular dynamics simulation approach

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Soon Heum [Linkoeping University, Linkoeping (Sweden); Kim, Na Yong; Nikitopoulos, Dimitris E.; Moldovan, Dorel [Louisiana State University, Baton Rouge (United States); Jha, Shantenu [Rutgers University, Piscataway (United States)

    2014-01-15

    Numerical approaches are presented to minimize the statistical errors inherently present due to finite sampling and the presence of thermal fluctuations in the molecular region of a hybrid computational fluid dynamics (CFD) - molecular dynamics (MD) flow solution. Near the fluid-solid interface the hybrid CFD-MD simulation approach provides a more accurate solution, especially in the presence of significant molecular-level phenomena, than the traditional continuum-based simulation techniques. It also involves less computational cost than the pure particle-based MD. Despite these advantages the hybrid CFD-MD methodology has been applied mostly in flow studies at high velocities, mainly because of the higher statistical errors associated with low velocities. As an alternative to the costly increase of the size of the MD region to decrease statistical errors, we investigate a few numerical approaches that reduce sampling noise of the solution at moderate-velocities. These methods are based on sampling of multiple simulation replicas and linear regression of multiple spatial/temporal samples. We discuss the advantages and disadvantages of each technique in the perspective of solution accuracy and computational cost.

  7. The narrative structure as a way to gain insight into peoples' experiences: one methodological approach.

    Science.gov (United States)

    Rejnö, Åsa; Berg, Linda; Danielson, Ella

    2014-09-01

    The narrative method is used in healthcare research, mostly in data collection but also in the analysis. Narrative approaches draw attention to how people tell about and create meaning of experiences. The aim of the article was to examine the narrative structure, the elements in the structure and their function and how these can be used in research to gain insights into experiences. Examples are taken from a material of narratives from a study where next of kin were asked to narrate their experiences of sudden and unexpected death from stroke. The narratives had a clear beginning, midpoint and ending. In the beginning, orientation of the narrated events was given. The narrated events were told to have a turning point constituted of complicating actions that lead to a resolution that solved the narrated event. The narratives were built up by multiple recaps into the narrated events and also consisted of asides - side narratives and flashbacks - events back in time. Use of a narrative structure can contribute with valuable information that might be missed with other analysis. The analysis can be used on its own, as a complement to other narrative analysis or even as a complement to other qualitative analysis.

  8. A Review of Methodological Approaches for the Design and Optimization of Wind Farms

    Directory of Open Access Journals (Sweden)

    José F. Herbert-Acero

    2014-10-01

    Full Text Available This article presents a review of the state of the art of the Wind Farm Design and Optimization (WFDO problem. The WFDO problem refers to a set of advanced planning actions needed to extremize the performance of wind farms, which may be composed of a few individual Wind Turbines (WTs up to thousands of WTs. The WFDO problem has been investigated in different scenarios, with substantial differences in main objectives, modelling assumptions, constraints, and numerical solution methods. The aim of this paper is: (1 to present an exhaustive survey of the literature covering the full span of the subject, an analysis of the state-of-the-art models describing the performance of wind farms as well as its extensions, and the numerical approaches used to solve the problem; (2 to provide an overview of the available knowledge and recent progress in the application of such strategies to real onshore and offshore wind farms; and (3 to propose a comprehensive agenda for future research.

  9. A Bayesian approach to the semi-analytic model of galaxy formation: methodology

    Science.gov (United States)

    Lu, Yu; Mo, H. J.; Weinberg, Martin D.; Katz, Neal

    2011-09-01

    We believe that a wide range of physical processes conspire to shape the observed galaxy population, but we remain unsure of their detailed interactions. The semi-analytic model (SAM) of galaxy formation uses multidimensional parametrizations of the physical processes of galaxy formation and provides a tool to constrain these underlying physical interactions. Because of the high dimensionality, the parametric problem of galaxy formation may be profitably tackled with a Bayesian-inference-based approach, which allows one to constrain theory with data in a statistically rigorous way. In this paper, we develop a SAM in the framework of Bayesian inference. We show that, with a parallel implementation of an advanced Markov chain Monte Carlo algorithm, it is now possible to rigorously sample the posterior distribution of the high-dimensional parameter space of typical SAMs. As an example, we characterize galaxy formation in the current Λ cold dark matter cosmology using the stellar mass function of galaxies as an observational constraint. We find that the posterior probability distribution is both topologically complex and degenerate in some important model parameters, suggesting that thorough explorations of the parameter space are needed to understand the models. We also demonstrate that because of the model degeneracy, adopting a narrow prior strongly restricts the model. Therefore, the inferences based on SAMs are conditional to the model adopted. Using synthetic data to mimic systematic errors in the stellar mass function, we demonstrate that an accurate observational error model is essential to meaningful inference.

  10. Cancer comortality patterns in schizophrenia and psychotic disorders: a new methodological approach for unique databases.

    Science.gov (United States)

    Ajdacic-Gross, Vladeta; Tschopp, Alois; Bopp, Matthias; Gutzwiller, Felix; Rössler, Wulf

    2014-03-01

    The aim of this study was to determine the pattern of cancer comortality in deaths registered with schizophrenia and psychotic disorders. It focused on the question of whether the proportions of different types of cancer diverge when they are co-registered with schizophrenia/psychotic disorders or with other causes of death in mortality statistics. We developed an analysis approach applicable to common mortality statistics data when no linkage with morbidity databases or other registers is possible. The analysis covered Swiss mortality data from a 39-year period (1969 - 2007) and was confined to the most frequent cancers. We applied a two-step case-control analysis with bootstrapping (1000 repetitions). The cases were defined by the cancer-schizophrenia registrations for each specific cancer, whereas the controls were matched from the remaining cases (matching criteria: sex, age, region, subperiod). Cancers with deviant standardized mortality ratios (SMRs) included stomach cancer (1.6; 2.2 after reweighting), lung cancer (0.8; 0.5 after reweighting) and breast cancer (1.6; 1.5 after reweighting). The comortality pattern of cancers in schizophrenia and psychotic disorders diverges from the pattern found in other co-registered causes of death. The relatively low frequency of lung cancers is particularly paradoxical in view of the smoking habits of schizophrenia patients.

  11. Investigating online harassment and offline violence among young people in Thailand: methodological approaches, lessons learned.

    Science.gov (United States)

    Ojanen, Timo T; Boonmongkon, Pimpawun; Samakkeekarom, Ronnapoom; Samoh, Nattharat; Cholratana, Mudjalin; Payakkakom, Anusorn; Guadamuz, Thomas E

    2014-01-01

    Violence in the physical (offline) world is a well-documented health and social issue among young people worldwide. In Southeast Asia, online harassment (defined as intentional behaviours to harm others through the Internet or through mobile devices) is less well documented. In this paper, we describe and critically discuss the mixed-methods data collection approach we used to build a contextualised understanding of offline violence and online harassment among 15- to 24-year-old students and out-of-school youth in Central Thailand. We mapped linkages between offline violence and online harassment, and with their possible correlates including gender, sexuality, and mobile media or Internet use. Data collection methods included in-depth interviews, focus group discussions and a custom-built, self-administered computerised survey. Using mixed methods enabled us to collect holistic qualitative/quantitative data from both students and out-of-school youth. In our discussion, we focus on gender, sexuality, class and ethnicity issues in recruiting out-of-school youth; definition and measurement issues; technical issues in using a computerised survey; ethical issues surrounding data collection from minors as well as privacy and confidentiality concerns in collecting data in both in-school and out-of-school settings; and the general implications of using mixed methods.

  12. A multi-criteria decision-making approach that combines fuzzy TOPSIS and DEA methodologies

    Directory of Open Access Journals (Sweden)

    Taylan, Osman

    2014-11-01

    Full Text Available Employee selection is a multi-criteria decision-making (MCDM problem for selecting suitable applicants from a ready pool. The selection aims to make use of their knowledge, relevant skills, and other characteristics to perform a specific job. The aim of this study is to develop a systematic approach for selecting the best candidates among the air traffic controllers (ATCs for aviation in Saudi Arabia. Three integrated methods were employed for decision-making in this study. First, a fuzzy decision tree was applied to determine the criteria weights, then the fuzzy Technique for Order Preference by Similarity to Ideal Solution (TOPSIS was employed to rank the attributes. In the last step, the Data Envelopment Analysis (DEA was used to transform the qualitative variables into quantitative equivalences. A survey was conducted by national and international decision- makers to elicit the necessary information on the criteria and sub-criteria of the air traffic control system. The decision problem was formulated by employing five criteria and ten applicants. The relationship between the fuzzy TOPSIS and fuzzy-weighted average was very positive for decision-making. The outcomes of the fuzzy TOPSIS and DEA encouraged the development of a decision support system for the selection of ATCs.

  13. Methodological approaches for studying the microbial ecology of drinking water distribution systems.

    Science.gov (United States)

    Douterelo, Isabel; Boxall, Joby B; Deines, Peter; Sekar, Raju; Fish, Katherine E; Biggs, Catherine A

    2014-11-15

    The study of the microbial ecology of drinking water distribution systems (DWDS) has traditionally been based on culturing organisms from bulk water samples. The development and application of molecular methods has supplied new tools for examining the microbial diversity and activity of environmental samples, yielding new insights into the microbial community and its diversity within these engineered ecosystems. In this review, the currently available methods and emerging approaches for characterising microbial communities, including both planktonic and biofilm ways of life, are critically evaluated. The study of biofilms is considered particularly important as it plays a critical role in the processes and interactions occurring at the pipe wall and bulk water interface. The advantages, limitations and usefulness of methods that can be used to detect and assess microbial abundance, community composition and function are discussed in a DWDS context. This review will assist hydraulic engineers and microbial ecologists in choosing the most appropriate tools to assess drinking water microbiology and related aspects. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Sustainable healthy eating behaviour of young adults: towards a novel methodological approach.

    Science.gov (United States)

    Pieniak, Zuzanna; Żakowska-Biemans, Sylwia; Kostyra, Eliza; Raats, Monique

    2016-07-15

    Food, nutrition and health policy makers are poised with two pertinent issues more than any other: obesity and climate change. Consumer research has focused primarily on specific areas of sustainable food, such as organic food, local or traditional food, meat substitution and/or reduction. More holistic view of sustainable healthy eating behaviour has received less attention, albeit that more research is emerging in this area. This study protocol that aims to investigate young consumers' attitudes and behaviour towards sustainable and healthy eating by applying a multidisciplinary approach, taking into account economical, marketing, public health and environmental related issues. In order to achieve this goal, consumers' reactions on interactive tailored informational messages about sustainable from social, environmental and economical point of view, as well as healthy eating behaviour in a group of young adults will be investigated using randomized controlled trial. To undertake the objective, the empirical research is divided into three studies: 1) Qualitative longitudinal research to explore openness to adopting sustainable healthy eating behaviour; 2) Qualitative research with the objective to develop a sustainable healthy eating behaviour index; and 3) Randomised controlled trial to describe consumers' reactions on interactive tailored messages about sustainable healthy eating in young consumers. To our knowledge, this is the first randomised controlled trial to test the young adults reactions to interactive tailor made messages on sustainable healthy eating using mobile smartphone app. Mobile applications designed to deliver intervention offer new possibilities to influence young adults behaviour in relation to diet and sustainability. Therefore, the study will provide valuable insights into drivers of change towards more environmentally sustainable and healthy eating behaviours. NCT02776410 registered May 16, 2016.

  15. Nutrition and physical activity programs for obesity treatment (PRONAF study: methodological approach of the project

    Directory of Open Access Journals (Sweden)

    Zapico Augusto G

    2012-12-01

    Full Text Available Abstract Background At present, scientific consensus exists on the multifactorial etiopatogenia of obesity. Both professionals and researchers agree that treatment must also have a multifactorial approach, including diet, physical activity, pharmacology and/or surgical treatment. These two last ones should be reserved for those cases of morbid obesities or in case of failure of the previous ones. The aim of the PRONAF study is to determine what type of exercise combined with caloric restriction is the most appropriate to be included in overweigth and obesity intervention programs, and the aim of this paper is to describe the design and the evaluation methods used to carry out the PRONAF study. Methods/design One-hundred nineteen overweight (46 males and 120 obese (61 males subjects aged 18–50 years were randomly assigned to a strength training group, an endurance training group, a combined strength + endurance training group or a diet and physical activity recommendations group. The intervention period was 22 weeks (in all cases 3 times/wk of training for 22 weeks and 2 weeks for pre and post evaluation. All subjects followed a hypocaloric diet (25-30% less energy intake than the daily energy expenditure estimated by accelerometry. 29–34% of the total energy intake came from fat, 14–20% from protein, and 50–55% from carbohydrates. The mayor outcome variables assesed were, biochemical and inflamatory markers, body composition, energy balance, physical fitness, nutritional habits, genetic profile and quality of life. 180 (75.3% subjects finished the study, with a dropout rate of 24.7%. Dropout reasons included: personal reasons 17 (28.8%, low adherence to exercise 3 (5.1%, low adherence to diet 6 (10.2%, job change 6 (10.2%, and lost interest 27 (45.8%. Discussion Feasibility of the study has been proven, with a low dropout rate which corresponds to the estimated sample size. Transfer of knowledge is foreseen as a spin-off, in order

  16. Nutrition and physical activity programs for obesity treatment (PRONAF study): methodological approach of the project.

    Science.gov (United States)

    Zapico, Augusto G; Benito, Pedro J; González-Gross, Marcela; Peinado, Ana B; Morencos, Esther; Romero, Blanca; Rojo-Tirado, Miguel A; Cupeiro, Rocio; Szendrei, Barbara; Butragueño, Javier; Bermejo, Maite; Alvarez-Sánchez, María; García-Fuentes, Miguel; Gómez-Candela, Carmen; Bermejo, Laura M; Fernandez-Fernandez, Ceila; Calderón, Francisco J

    2012-12-21

    At present, scientific consensus exists on the multifactorial etiopatogenia of obesity. Both professionals and researchers agree that treatment must also have a multifactorial approach, including diet, physical activity, pharmacology and/or surgical treatment. These two last ones should be reserved for those cases of morbid obesities or in case of failure of the previous ones. The aim of the PRONAF study is to determine what type of exercise combined with caloric restriction is the most appropriate to be included in overweigth and obesity intervention programs, and the aim of this paper is to describe the design and the evaluation methods used to carry out the PRONAF study. One-hundred nineteen overweight (46 males) and 120 obese (61 males) subjects aged 18-50 years were randomly assigned to a strength training group, an endurance training group, a combined strength + endurance training group or a diet and physical activity recommendations group. The intervention period was 22 weeks (in all cases 3 times/wk of training for 22 weeks and 2 weeks for pre and post evaluation). All subjects followed a hypocaloric diet (25-30% less energy intake than the daily energy expenditure estimated by accelerometry). 29-34% of the total energy intake came from fat, 14-20% from protein, and 50-55% from carbohydrates. The mayor outcome variables assesed were, biochemical and inflamatory markers, body composition, energy balance, physical fitness, nutritional habits, genetic profile and quality of life. 180 (75.3%) subjects finished the study, with a dropout rate of 24.7%. Dropout reasons included: personal reasons 17 (28.8%), low adherence to exercise 3 (5.1%), low adherence to diet 6 (10.2%), job change 6 (10.2%), and lost interest 27 (45.8%). Feasibility of the study has been proven, with a low dropout rate which corresponds to the estimated sample size. Transfer of knowledge is foreseen as a spin-off, in order that overweight and obese subjects can benefit from the results. The

  17. Language Policy and Methodology

    Science.gov (United States)

    Liddicoat, Antony J.

    2004-01-01

    The implementation of a language policy is crucially associated with questions of methodology. This paper explores approaches to language policy, approaches to methodology and the impact that these have on language teaching practice. Language policies can influence decisions about teaching methodologies either directly, by making explicit…

  18. Volcanic plumes fast detection: a methodological proposal for an integrated approach

    Science.gov (United States)

    Bernabeo, R. Alberto; Tositti, Laura; Brattich, Erika

    2017-04-01

    , running and control of the territory in which public safety is or may be at risk, and with reference to all those subjects that require a continuous cyclical process of observation, evaluation and interpretation. At the same time, a better knowledge of the chemical properties of volcanic emissions is a must for the future expansion foreseen in the next coming years in air transportation, for the health hazards that a volcanic ash cloud poses around the world and for a better understanding of the reduction already observed in GPS/GNSS satellite signals anytime a volcanic cloud covers the sky (thus obscuring the signal used by the navigation systems of modern aircraft), with associated safety risks. In this paper we propose a multitasking experimental approach based on the integrated use of remote sensing, aerosol sampling and chemical speciation together with the use of drones/tethered balloons equipped with aerosol sensors aimed at providing all the information which have been collected partially so far. The study will also collect information about the 3D distribution of all the aerosol properties described before with the aim of determining and helping the vertical resolution of data from remote sensing.

  19. Elimination Method of Multi-Criteria Decision Analysis (MCDA: A Simple Methodological Approach for Assessing Agricultural Sustainability

    Directory of Open Access Journals (Sweden)

    Byomkesh Talukder

    2017-02-01

    Full Text Available In the present world context, there is a need to assess the sustainability of agricultural systems. Various methods have been proposed to assess agricultural sustainability. Like in many other fields, Multi-Criteria Decision Analysis (MCDA has recently been used as a methodological approach for the assessment of agricultural sustainability. In this paper, an attempt is made to apply Elimination, a MCDA method, to an agricultural sustainability assessment, and to investigate its benefits and drawbacks. This article starts by explaining the importance of agricultural sustainability. Common MCDA types are discussed, with a description of the state-of-the-art method for incorporating multi-criteria and reference values for agricultural sustainability assessment. Then, a generic description of the Elimination Method is provided, and its modeling approach is applied to a case study in coastal Bangladesh. An assessment of the results is provided, and the issues that need consideration before applying Elimination to agricultural sustainability, are examined. Whilst having some limitations, the case study shows that it is applicable for agricultural sustainability assessments and for ranking the sustainability of agricultural systems. The assessment is quick compared to other assessment methods and is shown to be helpful for agricultural sustainability assessment. It is a relatively simple and straightforward analytical tool that could be widely and easily applied. However, it is suggested that appropriate care must be taken to ensure the successful use of the Elimination Method during the assessment process.

  20. A novel methodology based on contact angle hysteresis approach for surface changes monitoring in model PMMA-Corega Tabs system

    Science.gov (United States)

    Pogorzelski, Stanisław J.; Berezowski, Zdzisław; Rochowski, Paweł; Szurkowski, Janusz

    2012-02-01

    The aim of the paper is to propose a quantitative description of dental surface modifications, resulting from application of Corega and oral cavity liquids, with several surface parameters derived from liquid/solid contact angle measurements. In particular, to predict the long-term effectiveness of denture cleansers in prosthetics, it is necessary to determine surface wettability variations for model dental materials/probe liquid systems related to the contamination effect caused by substances found in the oral cavity. A novel simple low-cost methodology, based on liquid drop contact angle hysteresis CAH approach developed by Chibowski, was adopted to trace solid surface free energy changes in the model PMMA-Corega Tabs interfacial layer. Contact angle and its hysteresis were studied with a sessile drop-inclined plate method in contact with a cleanser (Corega Tabs) and model liquids found in the oral cavity. The apparent solid surface free energy, adsorptive film pressure, work of adhesion and spreading were derived from contact angle hysteresis data for both model solid surfaces (reference) and samples affected by different reactive liquids for a certain time. A time-dependent surface wettability changes of dentures were expressed quantitatively in terms of the corresponding variations of the surface energy parameters which turned out to be unequivocally related to the cleanser exposure time and polarity of the liquids applied to the dental material. The novel methodology appeared to be a useful tool for long term surface characterization of dental materials treated with surfactants-containing liquids capable of forming adhesive layers. The time of optimal use and effectiveness of cleansers are also reflected dynamically in the corresponding variations of the surface wettability parameters. Further studies on a large group of dental surface-probe liquid systems are required to specify the role played by other important factors (liquid polarity, pH and temperature).

  1. Examining Change in Metacognitive Knowledge and Metacognitive Control During Motor Learning: What Can be Learned by Combining Methodological Approaches?

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    Claire Sangster Jokić

    2014-04-01

    Full Text Available Growing recognition of the importance of understanding metacognitive behaviour as it occurs in everyday learning situations has prompted an expansion of the methodological approaches used to examine metacognition. This becomes especially pertinent when examining the process of metacognitive change, where 'on-line' observational approaches able to capture metacognitive performance as it occurs during socially-mediated learning are being increasingly applied. This study applied a mixed methods approach to examine children's metacognitive performance as it was exhibited during participation in an intervention program aimed at addressing motor performance difficulties. Participants in the study were ten 7-9 year old children with developmental coordination disorder (DCD, a condition characterized by poor motor coordination and difficulty acquiring motor-based tasks. All participants engaged in a 10-session program in which children were taught to use a problem-solving strategy for addressing motor performance difficulties. To examine children's metacognitive performance, sessions were video-taped and subsequently analysed using a quantitative observational coding method and an in-depth qualitative review of therapist-child interactions. This allowed for a fine-grained analysis of children's demonstration of metacognitive knowledge and control and how such performance evolved over the course of the program. Of particular interest was the finding that while children were often able to express task-specific knowledge, they failed to apply this knowledge during practice. Conversely, children were often able to demonstrate performance-based evidence for metacognitive control but were not able to make conscious reports of such skill following practice. This finding is consistent with models of metacognitive development which suggest that the emergence of performance-based metacognitive skills precede the ability for the conscious expression of

  2. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect and design for learning

    Directory of Open Access Journals (Sweden)

    Evangelia Triantafyllou

    2016-05-01

    Full Text Available One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class, while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens of learning design can promote the use of theories and methods to evaluate its effect on the achievement of learning objectives, and that it may draw attention to the employment of methods to gather learner responses. Moreover, a learning design approach can enforce the detailed description of activities, tools and resources used in specific flipped classroom models, and it can make educators more aware of the decisions that have to be taken and people who have to be involved when designing a flipped classroom. By using the LD-CM, this paper also draws attention to the importance of characteristics and values of different stakeholders (i.e. institutions, educators, learners, and external agents, which influence the design and success of flipped classrooms. Moreover, it looks at the teaching cycle from a flipped instruction model perspective and adjusts it to cater for the reflection loops educators are involved when designing, implementing and re-designing a flipped classroom. Finally, it highlights the effect of learning design on the guidance

  3. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect and design for learning

    Directory of Open Access Journals (Sweden)

    Evangelia Triantafyllou

    2016-05-01

    Full Text Available One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class, while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens of learning design can promote the use of theories and methods to evaluate its effect on the achievement of learning objectives, and that it may draw attention to the employment of methods to gather learner responses. Moreover, a learning design approach can enforce the detailed description of activities, tools and resources used in specific flipped classroom models, and it can make educators more aware of the decisions that have to be taken and people who have to be involved when designing a flipped classroom. By using the LD-CM, this paper also draws attention to the importance of characteristics and values of different stakeholders (i.e. institutions, educators, learners, and external agents, which influence the design and success of flipped classrooms. Moreover, it looks at the teaching cycle from a flipped instruction model perspective and adjusts it to cater for the reflection loops educators are involved when designing, implementing and re-designing a flipped classroom. Finally, it highlights the effect of learning design on the guidance

  4. Methodological approach to determine minor, considerable, and major treatment effects in the early benefit assessment of new drugs.

    Science.gov (United States)

    Skipka, Guido; Wieseler, Beate; Kaiser, Thomas; Thomas, Stefanie; Bender, Ralf; Windeler, Jürgen; Lange, Stefan

    2016-01-01

    At the beginning of 2011, the early benefit assessment of new drugs was introduced in Germany with the Act on the Reform of the Market for Medicinal Products (AMNOG). The Federal Joint Committee (G-BA) generally commissions the Institute for Quality and Efficiency in Health Care (IQWiG) with this type of assessment, which examines whether a new drug shows an added benefit (a positive patient-relevant treatment effect) over the current standard therapy. IQWiG is required to assess the extent of added benefit on the basis of a dossier submitted by the pharmaceutical company responsible. In this context, IQWiG was faced with the task of developing a transparent and plausible approach for operationalizing how to determine the extent of added benefit. In the case of an added benefit, the law specifies three main extent categories (minor, considerable, major). To restrict value judgements to a minimum in the first stage of the assessment process, an explicit and abstract operationalization was needed. The present paper is limited to the situation of binary data (analysis of 2 × 2 tables), using the relative risk as an effect measure. For the treatment effect to be classified as a minor, considerable, or major added benefit, the methodological approach stipulates that the (two-sided) 95% confidence interval of the effect must exceed a specified distance to the zero effect. In summary, we assume that our approach provides a robust, transparent, and thus predictable foundation to determine minor, considerable, and major treatment effects on binary outcomes in the early benefit assessment of new drugs in Germany. After a decision on the added benefit of a new drug by G-BA, the classification of added benefit is used to inform pricing negotiations between the umbrella organization of statutory health insurance and the pharmaceutical companies.

  5. Data-Based Comparison of Frequency Analysis Approaches: Methodological Framework and Application to Rainfall / Runoff Data in France

    Science.gov (United States)

    Lang, M.; Renard, B.; Kochanek, K.; Sauquet, E.; Garavaglia, F.; Paquet, E.; Soubeyroux, J.; Jourdain, S.; Veysseire, J.; Borchi, F.; Neppel, L.; Najib, K.; Arnaud, P.; Aubert, Y.; Auffray, A.

    2010-12-01

    Frequency analysis (FA) is one of the cornerstones of hazard quantification and risk assessment. Its basic objective is to estimate the distribution of some environmental variable X, e.g. annual maximum of the areal rainfall over some catchment, annual maximum flood, etc. This distribution can be used to estimate the exceedance probability of a given value of X (often expressed in terms of return period), or alternatively, to estimate the p-quantile of X, i.e. the value having an exceedance probability equal to 1-p. The estimation of quantiles is of primary importance since they are used to design civil engineering structures (e.g. dams, reservoirs, bridges) or to map hazard-prone areas where restrictions may be enforced (e.g. building restrictions in flood zones). FA has been the subject of extensive research, yielding an abundance of approaches. In practice, FA users and practitioners may feel lost facing such an abundance of methods. Consequently, several initiatives aimed at assisting users in realizing their analyses using best-practice methods. In addition to these end-user-oriented guideline documents, a large number of comparisons between competing methods have been reported in the research literature. The French National research project EXTRAFLO aims to perform a thorough comparison between FA approaches currently used in France, based on an extensive dataset of long series of rainfall and runoff. This poster provides a detailed description of the methodology used to perform the comparison, and presents preliminary results of its application to large rainfall and runoff datasets. More precisely, the following topics are presented: 1. Presentation of the datasets, including more than 1000 series of daily runoff and more than 2000 series of daily rainfall 2. Decomposition of the datasets into calibration/validation sub-samples 3. The issue of scrutinizing uncertainty estimates is discussed, and a method based on the concept of predictive distribution is

  6. A methodological approach to rapid assessment of a river flood in coastal waters. First test in the Po River delta

    Science.gov (United States)

    Campanelli, Alessandra; Bellafiore, Debora; Bensi, Manuel; Bignami, Francesco; Caccamo, Giuseppe; Celussi, Mauro; Del Negro, Paola; Ferrarin, Christian; Marini, Mauro; Paschini, Elio; Zaggia, Luca

    2014-05-01

    As part of the actions of the flagship project RITMARE (Ricerca ITaliana per il MARE) a daily oceanographic survey was performed on 29th November 2013 in front of the Po River delta (Northern Adriatic Sea). The Po river affects a large part of the Northern Adriatic Sea with strong implications on the circulation and functionality of the basin. Physical-chemical and biological properties of coastal waters were investigated after a moderate flood occurred around 25th-27th November. The cruise activities, carried out using a small research boat, were mainly focused on the test of a methodological approach to investigate the environment variability after a flood event in the framework of rapid assessment. The effects of the flood on the coastal waters, have been evaluated in the field using operational forecasts and real-time satellite imagery to assist field measurements and samplings. Surface satellite chlorophyll maps and surface salinity and current maps obtained from a numerical model forced by meteorological forecast and river data were analyzed to better identify the Po plume dispersion during and after the event in order to better locate offshore monitoring stations at the sea. Profiles of Temperature, Salinity, Turbidity, Fluorescence and Colored Dissolved Organic Matter (CDOM) throughout the water column were collected at 7 stations in front of the Po River delta. Sea surface water samples were also collected for the analysis of nutrients, Dissolved Organic Carbon (DOC) and CDOM (surface and bottom). The CDOM regulates the penetration of UV light throughout the water column and mediates photochemical reactions, playing an important role in many marine biogeochemical processes. Satellite images showed a strong color front that separates the higher-chlorophyll coastal water from the more oligotrophic mid-basin and eastern boundary Adriatic waters. In front of the river mouth, the surface layer was characterized by low salinity (14-15), high turbidity (8-11 NTU

  7. Theoretical and Methodological Approaches to Understanding Human Migration Patterns and their Utility in Forensic Human Identification Cases

    Directory of Open Access Journals (Sweden)

    Anastasia Holobinko

    2012-06-01

    Full Text Available Human migration patterns are of interest to scientists representing many fields. Theories have been posited to explain modern human evolutionary expansion, the diversity of human culture, and the motivational factors underlying an individual or group decision to migrate. Although the research question and subsequent approach may vary between disciplines, one thread is ubiquitous throughout most migration studies: why do humans migrate and what is the result of such an event? While the determination of individual attributes such as age, sex, and ancestry is often integral to migration studies, the positive identification of human remains is usually irrelevant. However, the positive identification of a deceased is paramount to a forensic investigation in which human remains have been recovered and must be identified. What role, if any, might the study of human movement patterns play in the interpretation of evidence associated with unidentified human remains? Due to increasing global mobility in the world's populations, it is not inconceivable that an individual might die far away from his or her home. If positive identification cannot immediately be made, investigators may consider various theories as to how or why a deceased ended up in a particular geographic location. While scientific evidence influences the direction of forensic investigations, qualitative evaluation can be an important component of evidence interpretation. This review explores several modern human migration theories and the methodologies utilized to identify evidence of human migratory movement before addressing the practical application of migration theory to forensic cases requiring the identification of human remains.

  8. METHODOLOGICAL APPROACHES TO FORMATION OF CONDITIONS OF TRANSITION TO STEADY DEVELOPMENT OF THE CREDIT ORGANIZATIONS OF REGION

    Directory of Open Access Journals (Sweden)

    O.I. Pechonik

    2006-03-01

    Full Text Available Formation of conditions of transition to steady development of the credit organizations assumes presence of scientific toolkit which should have methodological character and represent a set of scientific receptions, methods and principles of research to which definition given clause is devoted. The executed research has shown, that the logic and the scheme of the scientific analysis of processes of maintenance with bank service of economic system of region and formation of conditions of steady development of regional bank system should: to be based on statistical methods with use of system of national accounts in addition with the SWOT-analysis of bank system; formation of conditions of transition to steady development to be spent in a complex and comprehensively; management of process of transition to steady development of bank system should be carried out at active state participation within the limits of creation socially focused according to plan-market economy. At the given approach formation of conditions of transition of regional bank system on steady development, in our opinion, becomes possible.

  9. Quantifying the health impacts of air pollution under a changing climate-a review of approaches and methodology.

    Science.gov (United States)

    Sujaritpong, Sarunya; Dear, Keith; Cope, Martin; Walsh, Sean; Kjellstrom, Tord

    2014-03-01

    Climate change has been predicted to affect future air quality, with inevitable consequences for health. Quantifying the health effects of air pollution under a changing climate is crucial to provide evidence for actions to safeguard future populations. In this paper, we review published methods for quantifying health impacts to identify optimal approaches and ways in which existing challenges facing this line of research can be addressed. Most studies have employed a simplified methodology, while only a few have reported sensitivity analyses to assess sources of uncertainty. The limited investigations that do exist suggest that examining the health risk estimates should particularly take into account the uncertainty associated with future air pollution emissions scenarios, concentration-response functions, and future population growth and age structures. Knowledge gaps identified for future research include future health impacts from extreme air pollution events, interactions between temperature and air pollution effects on public health under a changing climate, and how population adaptation and behavioural changes in a warmer climate may modify exposure to air pollution and health consequences.

  10. Fundamental degradation mechanisms of layered oxide Li-ion battery cathode materials: Methodology, insights and novel approaches

    Energy Technology Data Exchange (ETDEWEB)

    Hausbrand, R., E-mail: hausbrand@surface.tu-darmstadt.de; Cherkashinin, G.; Ehrenberg, H.; Gröting, M.; Albe, K.; Hess, C.; Jaegermann, W.

    2015-02-15

    Graphical abstract: - Highlights: • Description of recent in operando and in situ analysis methodology. • Surface science approach using photoemission for analysis of cathode surfaces and interfaces. • Ageing and fatigue of layered oxide Li-ion battery cathode materials from the atomistic point of view. • Defect formation and electronic structure evolution as causes for cathode degradation. • Significance of interfacial energy alignment and contact potential for side reactions. - Abstract: This overview addresses the atomistic aspects of degradation of layered LiMO{sub 2} (M = Ni, Co, Mn) oxide Li-ion battery cathode materials, aiming to shed light on the fundamental degradation mechanisms especially inside active cathode materials and at their interfaces. It includes recent results obtained by novel in situ/in operando diffraction methods, modelling, and quasi in situ surface science analysis. Degradation of the active cathode material occurs upon overcharge, resulting from a positive potential shift of the anode. Oxygen loss and eventual phase transformation resulting in dead regions are ascribed to changes in electronic structure and defect formation. The anode potential shift results from loss of free lithium due to side reactions occurring at electrode/electrolyte interfaces. Such side reactions are caused by electron transfer, and depend on the electron energy level alignment at the interface. Side reactions at electrode/electrolyte interfaces and capacity fade may be overcome by the use of suitable solid-state electrolytes and Li-containing anodes.

  11. A response surface methodology and desirability approach for predictive modeling and optimization of cutting temperature in machining hardened steel

    Directory of Open Access Journals (Sweden)

    Ashok Kumar Sahoo

    2014-06-01

    Full Text Available This paper presents an experimental investigation on cutting temperature during hard turning of EN 24 steel (50 HRC using TiN coated carbide insert under dry environment. The prediction model is developed using response surface methodology and optimization of process parameter is performed by desirability approach. A stiff rise in cutting temperature is noticed when feed and cutting speed are elevated. The effect of depth of cut on cutting temperature is not that much significant compared with cutting speed and feed as observed from main effects plot. The response surface second order model presented high correlation coefficient (R2 = 0.992 explaining 99.2 % of the variability in the cutting temperature which indicates the goodness of fit for the model to the actual data and high statistical significance of the model. The experimental and predicted values are very close to each other. The calculated error for cutting temperature lies between 1.88-3.19 % during confirmation trial. Therefore, the developed second order model correlates the relationship of the cutting temperature with the process parameters with good degree of approximation. The optimal combination for process parameter is depth of cut at 0.2mm, feed of 0.1597 mm/rev and cutting speed of 70m/min. Based on these combination, the value of cutting temperature is 302.950C whose desirability is one.

  12. Current state of knowledge: outcomes research in children with mild to severe hearing impairment--approaches and methodological considerations.

    Science.gov (United States)

    Tomblin, Bruce; Hebbeler, Kathleen

    2007-12-01

    This paper will provide a backdrop to the others in this section on outcomes of children with mild to moderate sensorineural hearing loss. Our objective here is to provide an overview of the research approaches used to study the outcomes of these children to provide guidance for future studies of children with mild to severe sensorineural hearing impairment (HI). During the past 20 yr there has been a gradual coalescence of research practices concerned with examining outcomes. Those who have done this work have come from different disciplines and in many cases were motivated by different circumstances. As a result, terminology and perspectives on outcomes research often still bears the features of these different disciplines and objectives of this research. This paper is an effort to provide the reader with an overview of this research endeavor that will highlight the diversity of the work being conducted on outcomes but also emphasizes the common properties. This overview will emphasize the kinds of research questions that are asked in this area of research and the associated evidence obtained to address these research questions. After this initial section there will be a consideration of the methodological issues that need to be considered, particularly for outcome research in children with HI.

  13. Methodological approaches to planar and volumetric scintigraphic imaging of small volume targets with high spatial resolution and sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Mejia, J.; Galvis-Alonso, O.Y. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Faculdade de Medicina. Dept. de Biologia Molecular], e-mail: mejia_famerp@yahoo.com.br; Braga, J. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Div. de Astrofisica; Correa, R. [Instituto Nacional de Pesquisas Espaciais (INPE), Sao Jose dos Campos, SP (Brazil). Div. de Ciencia Espacial e Atmosferica; Leite, J.P. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Neurologia, Psiquiatria e Psicologia Medica; Simoes, M.V. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Clinica Medica

    2009-08-15

    Single-photon emission computed tomography (SPECT) is a non-invasive imaging technique, which provides information reporting the functional states of tissues. SPECT imaging has been used as a diagnostic tool in several human disorders and can be used in animal models of diseases for physiopathological, genomic and drug discovery studies. However, most of the experimental models used in research involve rodents, which are at least one order of magnitude smaller in linear dimensions than man. Consequently, images of targets obtained with conventional gamma-cameras and collimators have poor spatial resolution and statistical quality. We review the methodological approaches developed in recent years in order to obtain images of small targets with good spatial resolution and sensitivity. Multi pinhole, coded mask- and slit-based collimators are presented as alternative approaches to improve image quality. In combination with appropriate decoding algorithms, these collimators permit a significant reduction of the time needed to register the projections used to make 3-D representations of the volumetric distribution of target's radiotracers. Simultaneously, they can be used to minimize artifacts and blurring arising when single pinhole collimators are used. Representation images are presented, which illustrate the use of these collimators. We also comment on the use of coded masks to attain tomographic resolution with a single projection, as discussed by some investigators since their introduction to obtain near-field images. We conclude this review by showing that the use of appropriate hardware and software tools adapted to conventional gamma-cameras can be of great help in obtaining relevant functional information in experiments using small animals. (author)

  14. The pathogen- and incidence-based DALY approach: an appropriate [corrected] methodology for estimating the burden of infectious diseases.

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    Marie-Josée J Mangen

    Full Text Available In 2009, the European Centre for Disease Prevention and Control initiated the 'Burden of Communicable Diseases in Europe (BCoDE' project to generate evidence-based and comparable burden-of-disease estimates of infectious diseases in Europe. The burden-of-disease metric used was the Disability-Adjusted Life Year (DALY, composed of years of life lost due to premature death (YLL and due to disability (YLD. To better represent infectious diseases, a pathogen-based approach was used linking incident cases to sequelae through outcome trees. Health outcomes were included if an evidence-based causal relationship between infection and outcome was established. Life expectancy and disability weights were taken from the Global Burden of Disease Study and alternative studies. Disease progression parameters were based on literature. Country-specific incidence was based on surveillance data corrected for underestimation. Non-typhoidal Salmonella spp. and Campylobacter spp. were used for illustration. Using the incidence- and pathogen-based DALY approach the total burden for Salmonella spp. and Campylobacter spp. was estimated at 730 DALYs and at 1,780 DALYs per year in the Netherlands (average of 2005-2007. Sequelae accounted for 56% and 82% of the total burden of Salmonella spp. and Campylobacter spp., respectively. The incidence- and pathogen-based DALY methodology allows in the case of infectious diseases a more comprehensive calculation of the disease burden as subsequent sequelae are fully taken into account. Not considering subsequent sequelae would strongly underestimate the burden of infectious diseases. Estimates can be used to support prioritisation and comparison of infectious diseases and other health conditions, both within a country and between countries.

  15. Factors affecting the design of slow release formulations of herbicides based on clay-surfactant systems. A methodological approach.

    Directory of Open Access Journals (Sweden)

    María Del Carmen Galán-Jiménez

    Full Text Available A search for clay-surfactant based formulations with high percentage of the active ingredient, which can yield slow release of active molecules is described. The active ingredients were the herbicides metribuzin (MZ, mesotrione (MS and flurtamone (FL, whose solubilities were examined in the presence of four commercial surfactants; (i neutral: two berols (B048, B266 and an alkylpolyglucoside (AG6202; (ii cationic: an ethoxylated amine (ET/15. Significant percent of active ingredient (a.i. in the clay/surfactant/herbicide formulations could be achieved only when most of the surfactant was added as micelles. MZ and FL were well solubilized by berols, whereas MS by ET/15. Sorption of surfactants on the clay mineral sepiolite occurred mostly by sorption of micelles, and the loadings exceeded the CEC. Higher loadings were determined for B266 and ET/15. The sorption of surfactants was modeled by using the Langmuir-Scatchard equation which permitted the determination of binding coefficients that could be used for further predictions of the sorbed amounts of surfactants under a wide range of clay/surfactant ratios. A possibility was tested of designing clay-surfactant based formulations of certain herbicides by assuming the same ratio between herbicides and surfactants in the formulations as for herbicides incorporated in micelles in solution. Calculations indicated that satisfactory FL formulations could not be synthesized. The experimental fractions of herbicides in the formulations were in agreement with the predicted ones for MS and MZ. The validity of this approach was confirmed in in vitro release tests that showed a slowing down of the release of a.i. from the designed formulations relative to the technical products. Soil dissipation studies with MS formulations also showed improved bioactivity of the clay-surfactant formulation relative to the commercial one. This methodological approach can be extended to other clay-surfactant systems for

  16. Entropy and gravity concepts as new methodological indexes to investigate technological convergence: patent network-based approach.

    Directory of Open Access Journals (Sweden)

    Yongrae Cho

    Full Text Available The volatility and uncertainty in the process of technological developments are growing faster than ever due to rapid technological innovations. Such phenomena result in integration among disparate technology fields. At this point, it is a critical research issue to understand the different roles and the propensity of each element technology for technological convergence. In particular, the network-based approach provides a holistic view in terms of technological linkage structures. Furthermore, the development of new indicators based on network visualization can reveal the dynamic patterns among disparate technologies in the process of technological convergence and provide insights for future technological developments. This research attempts to analyze and discover the patterns of the international patent classification codes of the United States Patent and Trademark Office's patent data in printed electronics, which is a representative technology in the technological convergence process. To this end, we apply the physical idea as a new methodological approach to interpret technological convergence. More specifically, the concepts of entropy and gravity are applied to measure the activities among patent citations and the binding forces among heterogeneous technologies during technological convergence. By applying the entropy and gravity indexes, we could distinguish the characteristic role of each technology in printed electronics. At the technological convergence stage, each technology exhibits idiosyncratic dynamics which tend to decrease technological differences and heterogeneity. Furthermore, through nonlinear regression analysis, we have found the decreasing patterns of disparity over a given total period in the evolution of technological convergence. This research has discovered the specific role of each element technology field and has consequently identified the co-evolutionary patterns of technological convergence. These new findings

  17. The Rock Engineering System (RES) applied to landslide susceptibility zonation of the northeastern flank of Etna: methodological approach and results

    Science.gov (United States)

    Apuani, Tiziana; Corazzato, Claudia

    2015-04-01

    Ground deformations in the northeastern flank of Etna are well known. Despite only a few landslide events have been documented, these have significantly involved and damaged lifelines and buildings. These events are mainly related to the activity of the volcano-tectonic structures and associated seismicity, as in the case of the 2002 reactivation of the Presa landslide during an increased activity of the Pernicana fault system. In order to highlight the areal distribution of potentially unstable slopes based on a detailed, site-specific study of the factors responsible for landslide, and to ultimately contribute to risk management, a landslide susceptibility analysis of the northeastern flank of Etna in the Pernicana area was carried out, and a susceptibility map at 1:10.000 scale was produced, extending over an area of 168 km2. Different methods are proposed in the literature to obtain the regional distribution of potentially unstable slopes, depending on the problem scale, the slope dynamic evolution in the geological context, and the availability of data. Among semi-quantitative approaches, the present research combines the Rock Engineering System (RES) methodology with parameter zonation mapping in a GIS environment. The RES method represents a structured approach to manage a high number of interacting factors involved in the instability problem. A numerically coded, site-specific interaction matrix (IM) analyzes the cause-effect relationship in these factors, and calculates the degree of interactivity of each parameter, normalized by the overall interactivity of the system (weight factor). In the specific Etna case, the considered parameters are: slope attitude, lithotechnical properties (lithology, structural complexity, soil and rock mass quality), land use, tectonic structures, seismic activity (horizontal acceleration) and hydrogeological conditions (groundwater and drainage). Thematic maps are prepared at 1:10.000 scale for each of these parameters, and

  18. The Atomic Intrinsic Integration Approach: A Structured Methodology for the Design of Games for the Conceptual Understanding of Physics

    Science.gov (United States)

    Echeverria, Alejandro; Barrios, Enrique; Nussbaum, Miguel; Amestica, Matias; Leclerc, Sandra

    2012-01-01

    Computer simulations combined with games have been successfully used to teach conceptual physics. However, there is no clear methodology for guiding the design of these types of games. To remedy this, we propose a structured methodology for the design of conceptual physics games that explicitly integrates the principles of the intrinsic…

  19. A Comparison of Dorothy Heathcote's Informal Drama Methodology and a Formal Drama Approach in Influencing Self-Esteem of Preadolescents in a Christian Education Program.

    Science.gov (United States)

    Woody, Pamela Diane

    The purposes of this study were to compare the effectiveness of Dorothy Heathcote's informal drama methodology (referred to as ENCOUNTER) with a formal drama approach (PLAYS) in increasing self-esteem of preadolescents in a Christian education program, and to determine if positive correlation existed between self-esteem and intrinsic religious…

  20. Competitive removal of hazardous dyes from aqueous solution by MIL-68(Al): Derivative spectrophotometric method and response surface methodology approach

    Science.gov (United States)

    Tehrani, Mahnaz Saghanejhad; Zare-Dorabei, Rouholah

    2016-05-01

    MIL-68(Al) as a metal-organic framework (MOF) was synthesized and characterized by different techniques such as SEM, BET, FTIR, and XRD analysis. This material was then applied for simulations removal of malachite green (MG) and methylene blue (MB) dyes from aqueous solutions using second order derivative spectrophotometric method (SODS) which was applied to resolve the overlap between the spectra of these dyes. The dependency of dyes removal efficiency in binary solutions was examined and optimized toward various parameters including initial dye concentration, pH of the solution, adsorbent dosage and ultrasonic contact time using central composite design (CCD) under response surface methodology (RSM) approach. The optimized experimental conditions were set as pH 7.78, contact time 5 min, initial MB concentration 22 mg L- 1, initial MG concentration 12 mg L- 1 and adsorbent dosage 0.0055 g. The equilibrium data was fitted to isotherm models such as Langmuir, Freundlich and Tempkin and the results revealed the suitability of the Langmuir model. The maximum adsorption capacity of 666.67 and 153.85 mg g- 1 was obtained for MB and MG removal respectively. Kinetics data fitting to pseudo-first order, pseudo-second order and Elovich models confirmed the applicability of pseudo-second order kinetic model for description of the mechanism and adsorption rate. Dye-loaded MIL-68(Al) can be easily regenerated using methanol and applied for three frequent sorption/desorption cycles with high performance. The impact of ionic strength on removal percentage of both dyes in binary mixture was studied by using NaCl and KCl soluble salts at different concentrations. According to our findings, only small dosage of the proposed MOF is considerably capable to remove large amounts of dyes at room temperature and in very short time that is a big advantage of MIL-68(Al) as a promising adsorbent for adsorptive removal processes.

  1. A constructive approach for discovering new drug leads: Using a kernel methodology for the inverse-QSAR problem

    Directory of Open Access Journals (Sweden)

    Wong William WL

    2009-04-01

    Full Text Available Abstract Background The inverse-QSAR problem seeks to find a new molecular descriptor from which one can recover the structure of a molecule that possess a desired activity or property. Surprisingly, there are very few papers providing solutions to this problem. It is a difficult problem because the molecular descriptors involved with the inverse-QSAR algorithm must adequately address the forward QSAR problem for a given biological activity if the subsequent recovery phase is to be meaningful. In addition, one should be able to construct a feasible molecule from such a descriptor. The difficulty of recovering the molecule from its descriptor is the major limitation of most inverse-QSAR methods. Results In this paper, we describe the reversibility of our previously reported descriptor, the vector space model molecular descriptor (VSMMD based on a vector space model that is suitable for kernel studies in QSAR modeling. Our inverse-QSAR approach can be described using five steps: (1 generate the VSMMD for the compounds in the training set; (2 map the VSMMD in the input space to the kernel feature space using an appropriate kernel function; (3 design or generate a new point in the kernel feature space using a kernel feature space algorithm; (4 map the feature space point back to the input space of descriptors using a pre-image approximation algorithm; (5 build the molecular structure template using our VSMMD molecule recovery algorithm. Conclusion The empirical results reported in this paper show that our strategy of using kernel methodology for an inverse-Quantitative Structure-Activity Relationship is sufficiently powerful to find a meaningful solution for practical problems.

  2. Psychodynamic therapy from the perspective of self-organization. a concept of change and a methodological approach for empirical examination.

    Science.gov (United States)

    Gumz, Antje; Geyer, Michael; Brähler, Elmar

    2014-01-01

    Observations from therapeutic practice and a series of empirical findings, for example, those on discontinuous change in psychotherapeutic processes, suggest modelling the therapeutic process as a self-organizing system with stable and critical instable phases and abrupt transitions. Here, a concept of psychotherapeutic change is presented that applies self-organization theory to psychodynamic principles. The authors explain the observations and considerations that form the basis of the concept and present some connections with existing findings and concepts. On the basis of this model, they generated two hypotheses regarding the co-occurrence of instability and discontinuous change and the degree of synchrony between the therapist and patient. A study design to test these hypotheses was developed and applied to a single case (psychodynamic therapy). After each session, patient and therapist rated their interaction. A measure of instability was calculated across the resulting time series. Sequences of destabilization were observed. On the basis of points of extreme instability, the process was divided into phases. Local instability maxima were accompanied by significant discontinuous change. Destabilization was highly synchronous in therapist and patient ratings. The authors discussed the concept and the methodological procedure. The approach enables the operationalization of crises and to empirically assess the significance of critical phases and developments within the therapeutic relationship. We present a concept of change that applies self-organization theory to psychodynamic therapy. We empirically tested the hypotheses formulated in the concept based on an extract of 125 long-term psychodynamic therapy sessions. We continuously monitored the therapeutic interaction and calculated a measure of the instability of the assessments. We identified several sequences of stable and unstable episodes. Episodes of high instability were accompanied by discontinuous

  3. Convergence of IFRS and US GAAP in the field of lease: the impact of new methodological approaches for operating lease reporting

    Directory of Open Access Journals (Sweden)

    Patrik Svoboda

    2012-01-01

    Full Text Available Since 2002 the International Accounting Standards Board (IASB and the Financial Accounting Standards Board (FASB has begun significantly cooperate in the creation of standards based on the same principals. This is a process of convergence. It is realized through a series of sub-projects aimed at short-term or long-term period. Revenue recognition and lease reporting projects represent priority areas of convergence. The issue of leases belongs to one of the areas in which there have been, after a relatively long time, criticized the very principles applied in international accounting standards. The result of the convergence activities should be the creation of such methodological approaches of reporting the lease contracts on the side of lessee and then lessor that would eliminate the main weaknesses of the current system of reporting based on the classification of lease contracts in connection with the execution or non execution of the transfer of risks and benefits associated with the lease to the lessee. The aim of this paper is to evaluate the impact of implementation of the newly proposed methodological approach for lease reporting in the field of operating leases into the financial statements that will be affected by this change of methodology (balance sheet, income statement. Subsequently, it is evaluated also the impact into selected indicators of financial analysis with a focus on indicators, in whose construction are used items of statements that are significantly affected by the change of the methodological approach.

  4. LINEAR INFRASTRUCTURES THAT CHARACTERIZE A PAST LAND MANAGEMENT: THE MONTAGNOLA SENESE DRY STONE WALLS. A METHODOLOGICAL APPROACH OF ANALYSIS

    OpenAIRE

    2012-01-01

    The aim of this paper is to highlight the development of a methodology for studying linear infrastructures such as dry stone walls, characteristic of an earlier land management in the Siena countryside. The study area on which this methodology was tested is located in the Site of Community Importance (SCI) “Montagnola Senese”. It was chosen as an example of a historical form of agricultural and forest land management, partly related to the key presence of the above mentioned artifacts. This m...

  5. A methodological approach to comparing pros and cons of delocalizing villages: socio-economic and technical issues

    Science.gov (United States)

    Guadagno, Eleonora; Iovine, Giulio G. R.; Petrucci, Olga; Forciniti, Pinuccia R.

    2014-05-01

    Cavallerizzo have been analysed within the frame of a PhD thesis by one of the authors. The present study focuses on the Cavallerizzo case study to discuss a methodological approach useful to comparing pros and cons of delocalizing villages, aiming at properly considering socio-economic effects in addition to technical issues.

  6. [Methodology of the approach to express-estimation of radiation risk for public health under the influence of radionuclides present in the ground waters].

    Science.gov (United States)

    Korenkov, I P; Lashchenova, T N; Klochkova, N V

    2013-01-01

    The methodological approach for the express-estimation of the value of individual lifetime cancer risk due to the groundwater use by population for drinking is supposed. The calculation of risk is performed with the use of only the values of specific activity of 226Ra in underground water. The formulas for calculating the value of individual lifetime cancer risk in the groundwater use by the population in drinking aims for oral and inhalation routes of exposure are suggested.

  7. The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals. Part II

    DEFF Research Database (Denmark)

    Thyssen, Jacob P; Giménez-Arnau, Elena; Lepoittevin, Jean-Pierre

    2012-01-01

    To identify specific cases, classes or specific use situations of chemicals for which 'safety thresholds' or 'safety limits' were set (in regulations, standards, in scientific research/clinical work, etc.) and critically review the scientific and methodological parameters used to set those limits....

  8. Methodological approaches to analysis of agricultural countermeasures on radioactive contaminated areas: Estimation of effectiveness and comparison of different alternatives

    DEFF Research Database (Denmark)

    Yatsalo, B.I.; Hedemann Jensen, P.; Alexakhin, R.M.

    1997-01-01

    Methodological aspects of countermeasure analysis in the long-term period after a nuclear accident are discussed for agriculture countermeasures for illustrative purposes. The estimates of effectiveness fbr specific countermeasures as well as methods of justified action levels assessments and com...

  9. Nationalism Studies between Methodological Nationalism and Orientalism : An Alternative Approach Illustrated with the Case of El Greco in Toledo, Spain

    NARCIS (Netherlands)

    Storm, H.J.

    2015-01-01

    Methodological nationalism is still dominant in nationalism studies. When studying the construction of national identities, scholars generally limit their study to the borders of one nation-state, while only paying attention to members of that particular nation. Implicitly, foreign actors and influe

  10. Integration of FDG-PET/CT into external beam radiation therapy planning Technical aspects and recommendations on methodological approaches

    NARCIS (Netherlands)

    Thorwarth, D.; Beyer, T.; Boellaard, R.; De Ruysscher, D.; Grgic, A.; Lee, J. A.; Pietrzyk, U.; Sattler, B.; Schaefer, A.; van Elmpt, W.; Vogel, W.; Oyen, W. J. G.; Nestle, U.

    2012-01-01

    This work addresses the clinical adoption of FDG-PET/CT for image-guided radiation therapy planning (RIP). As such, important technical and methodological aspects of PET/CT-based RIP are reviewed and practical recommendations are given for routine patient management and clinical studies. First, rece

  11. Integration of FDG-PET/CT into external beam radiation therapy planning. Technical aspects and recommendations on methodological approaches.

    NARCIS (Netherlands)

    Thorwarth, D.; Beyer, T.; Boellaard, R.; Ruysscher, D. de; Grgic, A.; Lee, J.A.; Pietrzyk, U.; Sattler, B.; Schaefer, A.; Elmpt, W. van; Vogel, W.; Oyen, W.J.G.; Nestle, U.

    2012-01-01

    This work addresses the clinical adoption of FDG-PET/CT for image-guided radiation therapy planning (RTP). As such, important technical and methodological aspects of PET/CT-based RTP are reviewed and practical recommendations are given for routine patient management and clinical studies. First, rece

  12. Soft systems methodology as a potential approach to understanding non-motorised transport users in South Africa

    CSIR Research Space (South Africa)

    Van Rooyen, CE

    2016-07-01

    Full Text Available of this paper is to show the potential of using systems thinking and more particularly Soft Systems Methodology (SSM) as a practical and beneficial instrument that will guide BEPDPs with the ongoing learning process of understanding NMT users and their specific...

  13. Open verification methodology cookbook

    CERN Document Server

    Glasser, Mark

    2009-01-01

    Functional verification is an art as much as a science. It requires not only creativity and cunning, but also a clear methodology to approach the problem. The Open Verification Methodology (OVM) is a leading-edge methodology for verifying designs at multiple levels of abstraction. It brings together ideas from electrical, systems, and software engineering to provide a complete methodology for verifying large scale System-on-Chip (SoC) designs. OVM defines an approach for developing testbench architectures so they are modular, configurable, and reusable. This book is designed to help both novic

  14. An integrated quality function deployment and capital budgeting methodology for occupational safety and health as a systems thinking approach: the case of the construction industry.

    Science.gov (United States)

    Bas, Esra

    2014-07-01

    In this paper, an integrated methodology for Quality Function Deployment (QFD) and a 0-1 knapsack model is proposed for occupational safety and health as a systems thinking approach. The House of Quality (HoQ) in QFD methodology is a systematic tool to consider the inter-relationships between two factors. In this paper, three HoQs are used to consider the interrelationships between tasks and hazards, hazards and events, and events and preventive/protective measures. The final priority weights of events are defined by considering their project-specific preliminary weights, probability of occurrence, and effects on the victim and the company. The priority weights of the preventive/protective measures obtained in the last HoQ are fed into a 0-1 knapsack model for the investment decision. Then, the selected preventive/protective measures can be adapted to the task design. The proposed step-by-step methodology can be applied to any stage of a project to design the workplace for occupational safety and health, and continuous improvement for safety is endorsed by the closed loop characteristic of the integrated methodology.

  15. Combined deterministic and stochastic approaches for modeling the evolution of food products along the cold chain. Part I: Methodology

    OpenAIRE

    Flick, D.; Hoang, H.M.; Alvarez, G.; Laguerre, O.

    2012-01-01

    Many deterministic models have been developed to describe heat transfer in the cold chain and to predict the thermal and microbial evolution of food products. However, different product items will have different evolutions because of the variability of logistic supply chain, equipment design and operating conditions, etc. The objective of this study is to propose a general methodology to predict the evolution of food products and its variability along a cold chain. This evolution is chara...

  16. Using Design of Experiments and Response Surface Methodology as an Approach to Understand and Optimize Operational Air Power

    Science.gov (United States)

    2010-06-01

    Bendel, A. (1988), "Introduction to Taguchi Methodology," Taguchi Methods : Proceedings of the 1988 European Conference, London, Elsevier Applied Science...Progress, pp. 74-75, April 1990 Kackar, R.N. (1985), "Off-Line Quality Control, Parameter Design, and the Taguchi Method ," Journal of Quality...Ranjit R. (1990), A Primer on the Taguchi Method , New York, Van Nostrand Reinhold Unal, R., Stanley, D.O. and Joyner, R. (1993) , Propulsion

  17. [The triad configuration, humanist-existential-personal: a theoretical and methodological approach to psychiatric and mental health nursing].

    Science.gov (United States)

    Vietta, E P

    1995-01-01

    The author establishes a research line based on a theoretical-methodological referential for the qualitative investigation of psychiatric nursing and mental health. Aspects of humanist and existential philosophies and personalism were evaluated integrating them in a unique perspective. In order to maintain the scientific method of research in this referential the categorization process which will be adopted in this kind of investigation was explained.

  18. A Review of Scientific Approach in the Methodology of Social Science Research: Contributions of Kuhn, Popper and Lakatos

    OpenAIRE

    George, Justine

    2016-01-01

    Methodological understanding of the theory is as important as the theory itself, and must show the relationship between theoretical concepts used in the study and its expected conclusions. Measuring scientificity of each theory and then to categorie on the basis of its relative merit often difficult given available theories are concerned. However, theoretical contributions of Thomas Kuhn, Karl Popper and then Imre Lakatos are best to develop a framework to evaluate the progress of social scie...

  19. LINEAR INFRASTRUCTURES THAT CHARACTERIZE A PAST LAND MANAGEMENT: THE MONTAGNOLA SENESE DRY STONE WALLS. A METHODOLOGICAL APPROACH OF ANALYSIS

    Directory of Open Access Journals (Sweden)

    Emanuele Vazzano

    2012-06-01

    Full Text Available The aim of this paper is to highlight the development of a methodology for studying linear infrastructures such as dry stone walls, characteristic of an earlier land management in the Siena countryside. The study area on which this methodology was tested is located in the Site of Community Importance (SCI “Montagnola Senese”. It was chosen as an example of a historical form of agricultural and forest land management, partly related to the key presence of the above mentioned artifacts. This methodology was based on the analysis of a historical cadastre and the concurrent construction and updating of a L.I.S. (Land Information System processed in a GIS environment. In order to compare 1825 data about land use, land ownership and parcel boundaries of the current walls were surveyed during fieldwork through GPS handheld equipment. The results show quite a good correspondence between wall lines and cadastral parcel boundary lines, mostly in the woodland. The analysis of the study area brings out that the walls were designed to carry out different functions such as property boundary, to enclose fields and defend them from the entrance of livestock grazing in the woodland, and subdivide a same land property in different management portions both as cultivated fields and as woodland.

  20. A METHODOLOGY BASED ON AN ECOLOGICAL ECONOMY APPROACH FOR THE INTEGRATING MANAGEMENT OF THE SULPHUROUS WATER IN AN OIL REFINERY

    Directory of Open Access Journals (Sweden)

    Gabriel Orlando Lobelles Sardiñas

    2016-10-01

    Full Text Available Despite the current highly stringent international standards regulating the contaminating emissions to the environment, the Oil refinery of Cienfuegos is still generating liquid and gaseous emissions contaminating the environment. The construction of new units as part of the Refinery expansion leads to an increase of these emissions due to the lack of technologies for the reutilization of the sulphurous water. The objective of this paper is to propose a methodology for the integral management of the sulphurous residual water in the oil refining process, including the evaluation and selection of the most feasible technological variant to minimize the sulphur contamination of water and the resulting emissions during the process. The methodology is based on the ecological economy tools, allowing a comprehensible evaluation of six technological variants at the refinery of Cienfuegos. The Life Cycle Assessment was applied (ACV by its Spanish acronym, by means of the software SimaPro 7.1. It was evaluated through the Eco Speed Method, to minimize the possible uncertainty. An economic evaluation was performed, taking into account the external costs for a more comprehensive analysis, enabling, along with the ecological indicators, the selection of the best technological variant, achieving a methodology based on a comprehensive evaluation, and as a positive impact, the implementation of the chosen variant (V5, 98.27% of the process water was recovered, as well as the sulphur that recovered from 94 to 99.8 %, reducing the emissions from 12 200 to 120 mg/Nm3 as SO2.

  1. LANGUAGE POLICY AND METHODOLOGY

    Directory of Open Access Journals (Sweden)

    Antony J. Liddicoat

    2004-06-01

    Full Text Available The implementation of a language policy is crucially associated with questions of methodology. This paper explores approaches to language policy, approaches to methodology and the impact that these have on language teaching practice. Language policies can influence decisions about teaching methodologies either directly, by making explicit recommendations about the methods to be used in classroom practice, or indirectly, through the conceptualisation of language leaming which underlies the policy. It can be argued that all language policies have the potential to influence teaching methodologies indirectly and that those policies which have explicit recommendations about methodology are actually functioning of two levels. This allows for the possibility of conflict between the direct and indirect dimensions of the policy which results from an inconsistency between the explicitly recommended methodology and the underlying conceptualisation of language teaching and learning which informs the policy.

  2. The Methodology of Magpies

    Science.gov (United States)

    Carter, Susan

    2014-01-01

    Arts/Humanities researchers frequently do not explain methodology overtly; instead, they "perform" it through their use of language, textual and historic cross-reference, and theory. Here, methodologies from literary studies are shown to add to Higher Education (HE) an exegetical and critically pluralist approach. This includes…

  3. Menopause and Methodological Doubt

    Science.gov (United States)

    Spence, Sheila

    2005-01-01

    Menopause and methodological doubt begins by making a tongue-in-cheek comparison between Descartes' methodological doubt and the self-doubt that can arise around menopause. A hermeneutic approach is taken in which Cartesian dualism and its implications for the way women are viewed in society are examined, both through the experiences of women…

  4. The Methodology of Magpies

    Science.gov (United States)

    Carter, Susan

    2014-01-01

    Arts/Humanities researchers frequently do not explain methodology overtly; instead, they "perform" it through their use of language, textual and historic cross-reference, and theory. Here, methodologies from literary studies are shown to add to Higher Education (HE) an exegetical and critically pluralist approach. This includes…

  5. Menopause and Methodological Doubt

    Science.gov (United States)

    Spence, Sheila

    2005-01-01

    Menopause and methodological doubt begins by making a tongue-in-cheek comparison between Descartes' methodological doubt and the self-doubt that can arise around menopause. A hermeneutic approach is taken in which Cartesian dualism and its implications for the way women are viewed in society are examined, both through the experiences of women…

  6. Methodological advances

    Directory of Open Access Journals (Sweden)

    Lebreton, J.-D.

    2004-06-01

    Full Text Available The study of population dynamics has long depended on methodological progress. Among many striking examples, continuous time models for populations structured in age (Sharpe & Lotka, 1911 were made possible by progress in the mathematics of integral equations. Therefore the relationship between population ecology and mathematical and statistical modelling in the broad sense raises a challenge in interdisciplinary research. After the impetus given in particular by Seber (1982, the regular biennial EURING conferences became a major vehicle to achieve this goal. It is thus not surprising that EURING 2003 included a session entitled “Methodological advances”. Even if at risk of heterogeneity in the topics covered and of overlap with other sessions, such a session was a logical way of ensuring that recent and exciting new developments were made available for discussion, further development by biometricians and use by population biologists. The topics covered included several to which full sessions were devoted at EURING 2000 (Anderson, 2001 such as: individual covariates, Bayesian methods, and multi–state models. Some other topics (heterogeneity models, exploited populations and integrated modelling had been addressed by contributed talks or posters. Their presence among “methodological advances”, as well as in other sessions of EURING 2003, was intended as a response to their rapid development and potential relevance to biological questions. We briefly review all talks here, including those not published in the proceedings. In the plenary talk, Pradel et al. (in prep. developed GOF tests for multi–state models. Until recently, the only goodness–of–fit procedures for multistate models were ad hoc, and non optimal, involving use of standard tests for single state models (Lebreton & Pradel, 2002. Pradel et al. (2003 proposed a general approach based in particular on mixtures of multinomial distributions. Pradel et al. (in prep. showed

  7. Human Computer Interactions in Next-Generation of Aircraft Smart Navigation Management Systems: Task Analysis and Architecture under an Agent-Oriented Methodological Approach

    Directory of Open Access Journals (Sweden)

    José M. Canino-Rodríguez

    2015-03-01

    Full Text Available The limited efficiency of current air traffic systems will require a next-generation of Smart Air Traffic System (SATS that relies on current technological advances. This challenge means a transition toward a new navigation and air-traffic procedures paradigm, where pilots and air traffic controllers perform and coordinate their activities according to new roles and technological supports. The design of new Human-Computer Interactions (HCI for performing these activities is a key element of SATS. However efforts for developing such tools need to be inspired on a parallel characterization of hypothetical air traffic scenarios compatible with current ones. This paper is focused on airborne HCI into SATS where cockpit inputs came from aircraft navigation systems, surrounding traffic situation, controllers’ indications, etc. So the HCI is intended to enhance situation awareness and decision-making through pilot cockpit. This work approach considers SATS as a system distributed on a large-scale with uncertainty in a dynamic environment. Therefore, a multi-agent systems based approach is well suited for modeling such an environment. We demonstrate that current methodologies for designing multi-agent systems are a useful tool to characterize HCI. We specifically illustrate how the selected methodological approach provides enough guidelines to obtain a cockpit HCI design that complies with future SATS specifications.

  8. Human computer interactions in next-generation of aircraft smart navigation management systems: task analysis and architecture under an agent-oriented methodological approach.

    Science.gov (United States)

    Canino-Rodríguez, José M; García-Herrero, Jesús; Besada-Portas, Juan; Ravelo-García, Antonio G; Travieso-González, Carlos; Alonso-Hernández, Jesús B

    2015-03-04

    The limited efficiency of current air traffic systems will require a next-generation of Smart Air Traffic System (SATS) that relies on current technological advances. This challenge means a transition toward a new navigation and air-traffic procedures paradigm, where pilots and air traffic controllers perform and coordinate their activities according to new roles and technological supports. The design of new Human-Computer Interactions (HCI) for performing these activities is a key element of SATS. However efforts for developing such tools need to be inspired on a parallel characterization of hypothetical air traffic scenarios compatible with current ones. This paper is focused on airborne HCI into SATS where cockpit inputs came from aircraft navigation systems, surrounding traffic situation, controllers' indications, etc. So the HCI is intended to enhance situation awareness and decision-making through pilot cockpit. This work approach considers SATS as a system distributed on a large-scale with uncertainty in a dynamic environment. Therefore, a multi-agent systems based approach is well suited for modeling such an environment. We demonstrate that current methodologies for designing multi-agent systems are a useful tool to characterize HCI. We specifically illustrate how the selected methodological approach provides enough guidelines to obtain a cockpit HCI design that complies with future SATS specifications.

  9. A methodological approach to assess sensitivity to desertification in two sub-Saharan urban areas: Ouagadougou (Burkina Faso) and Saint Louis (Senegal)

    Science.gov (United States)

    Iavazzo, P.; Terracciano, S.; Topa, M. E.; Adamo, P.; Coly, A.; De Paola, F.; Giordano, S.; Giugni, M.; Touré, H.

    2012-04-01

    The United Nations Convention to Combat Desertification (UNCCD) defines desertification as "land degradation in arid, semi-arid and dry sub-humid areas resulting from various factors, including climatic variations and human activities". Desertification is regarded as one of the major global environmental problems of the 21st century and the African sub-Sahara is often quoted as the most seriously affected region with a significant loss of biological and economic productivity of the land. In this geographic area, desertification processes are usually generated by soil erosion due to climate characteristics and fluctuations, unsustainable land uses, overgrazing and inappropriate agricultural practices. Preventing desertification requires an improved understanding of its causes, impact, degree and association with climate, soil, water, land cover, socio-economic factors and their combined effects. The development of methodologies capable of managing large amounts of data in an integrated approach is needed because of the complexity and variety of forms of desertification processes. The study was carried out within the FP7-ENV-2010 CLUVA project (CLimate change and Urban Vulnerability in Africa), aimed to estimate the sensitivity to land degradation in the urban and peri-urban areas of both Ouagadougou (Burkina Faso) and Saint Louis (Senegal) cities. The approach was based on the implementation and adaptation of the modeling methodology developed within the MEDALUS project (MEditerranean Desertification and Land Use). The model is characterized by a multi-factor approach based on the assessment of both environmental quality indicators (climate, soil, vegetation) and anthropogenic factors (land management). The methodology is adaptable to the local conditions, considering that some key indicators can be operationally defined through the inclusion or exclusion of parameters and the scores assigned in order to match the specific relevance of the factors. All local data

  10. A methodological combined framework for roadmapping biosensor research: a fault tree analysis approach within a strategic technology evaluation frame.

    Science.gov (United States)

    Siontorou, Christina G; Batzias, Fragiskos A

    2014-03-01

    Biosensor technology began in the 1960s to revolutionize instrumentation and measurement. Despite the glucose sensor market success that revolutionized medical diagnostics, and artificial pancreas promise currently the approval stage, the industry is reluctant to capitalize on other relevant university-produced knowledge and innovation. On the other hand, the scientific literature is extensive and persisting, while the number of university-hosted biosensor groups is growing. Considering the limited marketability of biosensors compared to the available research output, the biosensor field has been used by the present authors as a suitable paradigm for developing a methodological combined framework for "roadmapping" university research output in this discipline. This framework adopts the basic principles of the Analytic Hierarchy Process (AHP), replacing the lower level of technology alternatives with internal barriers (drawbacks, limitations, disadvantages), modeled through fault tree analysis (FTA) relying on fuzzy reasoning to count for uncertainty. The proposed methodology is validated retrospectively using ion selective field effect transistor (ISFET) - based biosensors as a case example, and then implemented prospectively membrane biosensors, putting an emphasis on the manufacturability issues. The analysis performed the trajectory of membrane platforms differently than the available market roadmaps that, considering the vast industrial experience in tailoring and handling crystallic forms, suggest the technology path of biomimetic and synthetic materials. The results presented herein indicate that future trajectories lie along with nanotechnology, and especially nanofabrication and nano-bioinformatics, and focused, more on the science-path, that is, on controlling the natural process of self-assembly and the thermodynamics of bioelement-lipid interaction. This retained the nature-derived sensitivity of the biosensor platform, pointing out the differences

  11. Constructing a question bank based on script concordance approach as a novel assessment methodology in surgical education.

    Science.gov (United States)

    Aldekhayel, Salah A; Alselaim, Nahar A; Magzoub, Mohi Eldin; Al-Qattan, Mohammad M; Al-Namlah, Abdullah M; Tamim, Hani; Al-Khayal, Abdullah; Al-Habdan, Sultan I; Zamakhshary, Mohammed F

    2012-10-24

    Script Concordance Test (SCT) is a new assessment tool that reliably assesses clinical reasoning skills. Previous descriptions of developing SCT-question banks were merely subjective. This study addresses two gaps in the literature: 1) conducting the first phase of a multistep validation process of SCT in Plastic Surgery, and 2) providing an objective methodology to construct a question bank based on SCT. After developing a test blueprint, 52 test items were written. Five validation questions were developed and a validation survey was established online. Seven reviewers were asked to answer this survey. They were recruited from two countries, Saudi Arabia and Canada, to improve the test's external validity. Their ratings were transformed into percentages. Analysis was performed to compare reviewers' ratings by looking at correlations, ranges, means, medians, and overall scores. Scores of reviewers' ratings were between 76% and 95% (mean 86% ± 5). We found poor correlations between reviewers (Pearson's: +0.38 to -0.22). Ratings of individual validation questions ranged between 0 and 4 (on a scale 1-5). Means and medians of these ranges were computed for each test item (mean: 0.8 to 2.4; median: 1 to 3). A subset of test items comprising 27 items was generated based on a set of inclusion and exclusion criteria. This study proposes an objective methodology for validation of SCT-question bank. Analysis of validation survey is done from all angles, i.e., reviewers, validation questions, and test items. Finally, a subset of test items is generated based on a set of criteria.

  12. Methodological approach and tools for systems thinking in health systems research: technical assistants' support of health administration reform in the Democratic Republic of Congo as an application.

    Science.gov (United States)

    Ribesse, Nathalie; Bossyns, Paul; Marchal, Bruno; Karemere, Hermes; Burman, Christopher J; Macq, Jean

    2017-03-01

    In the field of development cooperation, interest in systems thinking and complex systems theories as a methodological approach is increasingly recognised. And so it is in health systems research, which informs health development aid interventions. However, practical applications remain scarce to date. The objective of this article is to contribute to the body of knowledge by presenting the tools inspired by systems thinking and complexity theories and methodological lessons learned from their application. These tools were used in a case study. Detailed results of this study are in process for publication in additional articles. Applying a complexity 'lens', the subject of the case study is the role of long-term international technical assistance in supporting health administration reform at the provincial level in the Democratic Republic of Congo. The Methods section presents the guiding principles of systems thinking and complex systems, their relevance and implication for the subject under study, and the existing tools associated with those theories which inspired us in the design of the data collection and analysis process. The tools and their application processes are presented in the results section, and followed in the discussion section by the critical analysis of their innovative potential and emergent challenges. The overall methodology provides a coherent whole, each tool bringing a different and complementary perspective on the system.

  13. Scenario development methodologies

    Energy Technology Data Exchange (ETDEWEB)

    Eng, T. [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Hudson, J. [Rock Engineering Consultants, Welwyn Garden City, Herts (United Kingdom); Stephansson, O. [Royal Inst. of Tech., Stockholm (Sweden). Div. of Engineering Geology; Skagius, K.; Wiborgh, M. [Kemakta, Stockholm (Sweden)

    1994-11-01

    In the period 1981-1994, SKB has studied several methodologies to systematize and visualize all the features, events and processes (FEPs) that can influence a repository for radioactive waste in the future. All the work performed is based on the terminology and basic findings in the joint SKI/SKB work on scenario development presented in the SKB Technical Report 89-35. The methodologies studied are (a) Event tree analysis, (b) Influence diagrams and (c) Rock Engineering Systems (RES) matrices. Each one of the methodologies is explained in this report as well as examples of applications. One chapter is devoted to a comparison between the two most promising methodologies, namely: Influence diagrams and the RES methodology. In conclusion a combination of parts of the Influence diagram and the RES methodology is likely to be a promising approach. 26 refs.

  14. Making the narrative walk-in-real-time methodology relevant for public health intervention: towards an integrative approach.

    Science.gov (United States)

    Miaux, Sylvie; Drouin, Louis; Morency, Patrick; Paquin, Sophie; Gauvin, Lise; Jacquemin, Christophe

    2010-11-01

    The purpose of this article is to describe a novel approach for understanding the subjective experience of being a pedestrian in urban settings. In so doing, we take into account the "experience of the body in movement" as described in different theories and according to different methods, and develop a tool to allow citizens and urban planners to exchange ideas about how to make cities more walkable. Finally, we present the adaptation of the approach for use in public health and provide a rationale for its more widespread use in place and health research. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. The Challenge of Integrating OHS into Industrial Project Risk Management: Proposal of a Methodological Approach to Guide Future Research (Case of Mining Projects in Quebec, Canada

    Directory of Open Access Journals (Sweden)

    Adel Badri

    2015-06-01

    Full Text Available Although risk management tools are put to good use in many industrial sectors, some large projects have been met with numerous problems due to failure to take occupational health and safety (OHS into consideration. In spite of the high level of risk and uncertainty associated with many industrial projects, the number of studies of methods for managing all known risks systematically remains small. Under effervescent economic conditions, industries must meet several challenges associated with frequent project start-ups. In highly complex and uncertain environments, rigorous management of risk remains indispensable for avoiding threats to the success of projects. Many businesses seek continually to create and improve integrated approaches to risk management. This article puts into perspective the complexity of the challenge of integrating OHS into industrial project risk management. A conceptual and methodological approach is proposed to guide future research focused on meeting this challenge. The approach is based on applying multi-disciplinary research modes to a complex industrial context in order to identify all scenarios likely to contain threats to humans or the environment. A case study is used to illustrate the potential of the proposed approach for application and its contribution to meeting the challenge of taking OHS into consideration. On-site researchers were able to develop a new approach that helped two mining companies in Quebec (Canada to achieve successful integration of OHS into expansion projects.

  16. Synergies between Theoretical Approaches to Mathematics Education with Technology: A Case Study through a Cross-Analysis Methodology

    Science.gov (United States)

    Maracci, Mirko; Cazes, Claire; Vandebrouck, Fabrice; Mariotti, Maria Alessandra

    2013-01-01

    Mathematics education as a research domain is characterized by a plurality of theoretical approaches. Acknowledging the existence of such diversity and the risks of an excessive theoretical fragmentation does not mean to search for a unifying theory but to urge the community to develop strategies for coping with this diversity. This article is…

  17. Methodology for determination of pipeline trenching depth in shore approach areas using local environmental data and numerical models

    Energy Technology Data Exchange (ETDEWEB)

    Rego, Valeria S.; Braga, Vinicius R.; Mansur Barros, Claudio R.; Martinez, Marcio B.; Piaulino, Pedro O.; Teixeira, Marcelo J.B. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Gusmao, Luiz A.B. [Aquamodelo Consultoria e Engenharia Ltda., Rio de Janeiro, RJ (Brazil)

    2005-07-01

    Shore-approach engineering design of pipelines, including pipeline trenching specifications, presents great complexity due to comparatively (in relation to deeper waters) harsher environmental conditions and highly dynamic interaction between waves, currents and sediment transport. In general, pipelines should be buried in beach areas, but depending on the sea conditions and the trench depth, the pipeline may become unburied during its operational life. Unburied pipelines at shore-approach areas may suffer the action of unpredicted loads. The uncertainty related to these loads may decrease the structural reliability of the pipeline. the problem to be solved is how deep a pipeline requires to be trenched at the shore approach area, considering that it should be kept in this condition throughout its design life. This should be achieved with a cost-effective solution, assuring the structural reliability of the pipeline during operation, in addition to considering the feasibility of the project. Directional wave, water level, beach profile and sediment grain distribution data in the shore approach area permit determination of typical profiles, median sediment grain size, extreme and frequent wave and water level conditions, which are parameters to be used to simulate beach profile evolution through numerical model SBEACH and estimate the minimum burial depth profile. (author)

  18. Methodological Approach for the Sustainability Assessment of Development Cooperation Projects for Built Innovations Based on the SDGs and Life Cycle Thinking

    Directory of Open Access Journals (Sweden)

    Stephanie D. Maier

    2016-10-01

    Full Text Available This paper describes a methodological approach for a sustainability assessment of development cooperation projects. Between the scientific disciplines there is no agreement on the term of “sustainability”. Whereas the definition of sustainability within the context of development cooperation frequently highlights the long-term success of an intervention, the United Nations herald the inclusion of social, economic and environmental aspects. This paper proposes to bridge this gap by providing an analytical framework that uses nine impact category groups based on thematic priorities of sustainable development derived from the Sustainable Development Goals. Additionally, the long-term effectiveness of a project is taken into consideration. These impact category groups comprise the analytical framework, which is investigated by the Life Cycle Assessment and an indicator-based analysis. These data are obtained through empirical social research and the LCA inventory. The underlying concept is based on life cycle thinking. Taking up a multi-cycle model this study establishes two life cycles: first, the project management life cycle; and, second, the life cycle of a project’s innovation. The innovation’s life cycle is identified to have the greatest impact on the target region and the local people and is consequently of primary interest. This methodological approach enables an ex-post sustainability assessment of a built innovation of a development cooperation project and is tested on a case study on Improved Cooking Stoves in Bangladesh.

  19. ACTIVE TEACHING-LEARNING METHODOLOGY TO APPROACH CARBOHYDRATE AND LIPID METABOLISM: An interdisciplinary strategy that involved the Moodle tool in the development of Problem Based Learning

    Directory of Open Access Journals (Sweden)

    J. M.P. Borges

    2015-08-01

    Full Text Available Highlight the relevance of topics studied for professional practice and associate approaches provided by different areas of knowledge are pointed as essential aspects for significant learning. Contextualize the study of metabolic pathways, linking the clinical use and expanding the vision with the approach of cellular and molecular biology discipline was the motivation for the development of the strategy described and evaluated here. In this work, starting from the concept of active methodology of teaching and learning was developed a methodological strategy to approach the carbohydrate and lipid metabolism. This strategy included: questioning the content through the clinical case study on diabetes mellitus and hypercholesterolemia, individual and collective study in the external space the classroom with the help of Moodle tool, classroom discussion accompanied by the teacher, preparation of seminar, evaluation of the content through individual written test and evaluation of the method. Analysis of student involvement with method indicates an average frequency of 98% in the practical class of Biochemistry discipline, effective participation in the preparation of seminars, an increase of 2 points in average of individual written evaluation. As for the fact that the cases were studied in two curricular components, the answers show that 92% of students feel more compression. Only 6% of students think  unnecessary to interdisciplinary approach. As for the different steps of the method, the answers show that 99% of students consider how relevant the initial self-study and discussions in class. However, only 50% of students appreciated the use of Moodle tool. Thus, student responses indicated the perception of the effectiveness of the method for their ability to: stimulate interest in learning, stimulate the search for answers through research and the building of learning.

  20. Ultrasound-assisted extraction of pectins from grape pomace using citric acid: a response surface methodology approach.

    Science.gov (United States)

    Minjares-Fuentes, R; Femenia, A; Garau, M C; Meza-Velázquez, J A; Simal, S; Rosselló, C

    2014-06-15

    An ultrasound-assisted procedure for the extraction of pectins from grape pomace with citric acid as the extracting agent was established. A Box-Behnken design (BBD) was employed to optimize the extraction temperature (X1: 35-75°C), extraction time (X2: 20-60 min) and pH (X3: 1.0-2.0) to obtain a high yield of pectins with high average molecular weight (MW) and degree of esterification (DE) from grape pomace. Analysis of variance showed that the contribution of a quadratic model was significant for the pectin extraction yield and for pectin MW whereas the DE of pectins was more influenced by a linear model. An optimization study using response surface methodology was performed and 3D response surfaces were plotted from the mathematical model. According to the RSM model, the highest pectin yield (∼32.3%) can be achieved when the UAE process is carried out at 75°C for 60 min using a citric acid solution of pH 2.0. These pectic polysaccharides, composed mainly by galacturonic acid units (ultrasound-assisted extraction could be a good option for the extraction of functional pectins with citric acid from grape pomace at industrial level. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. A new methodology for pixel-quantitative precipitation nowcasting using a pyramid Lucas Kanade optical flow approach

    Science.gov (United States)

    Liu, Yu; Xi, Du-Gang; Li, Zhao-Liang; Hong, Yang

    2015-10-01

    Short-term high-resolution Quantitative Precipitation Nowcasting (QPN) has important implications for navigation, flood forecasting, and other hydrological and meteorological concerns. This study proposes a new algorithm called Pixel-based QPN using the Pyramid Lucas-Kanade Optical Flow method (PPLK), which comprises three steps: employing a Pyramid Lucas-Kanade Optical Flow method (PLKOF) to estimate precipitation advection, projecting rainy clouds by considering the advection and evolution pixel by pixel, and interpolating QPN imagery based on the space-time continuum of cloud patches. The PPLK methodology was evaluated with 2338 images from the geostationary meteorological satellite Fengyun-2F (FY-2F) of China and compared with two other advection-based methods, i.e., the maximum correlation method and the Horn-Schunck Optical Flow scheme. The data sample covered all intensive observations since the launch of FY-2F, despite covering a total of only approximately 10 days. The results show that the PPLK performed better than the algorithms used for comparison, demonstrating less time expenditure, more effective cloud tracking, and improved QPN accuracy.

  2. The innovative approaches to the investigation of preconditions for creation management methodology of an enterprise`s logistics expenses

    Directory of Open Access Journals (Sweden)

    T.V. Shcholokova

    2013-09-01

    , of conception of marketing logistic and conception of integrated logistic. It should be noted that the innovative achievement of neoinstitution consists in unfree of chargeness of informative resource as component part of transaction. Possibility to use the attribute of transactions for the predictable and legal fixing of firm at the user market appeared in practice of logistic management. The price mechanism of foreign market by means of transactions began to influence on the acceptance of economic decisions into a firm and stipulated appearance of transactional expenses as to the inalienable constituent of logistic expenses. In spite of wide spectrum of theoretical researches of economic issues of the day within the framework of theoretic and economic schools of neoinstitution the reflection of problem of design of logistic processes that make a functional environment for appearance of logistic expenses is absent in their works. Reason of this phenomenon is characterized by the concept of compatible object of research which is absent in the neoinstitutional theory of economic analysis compatible enterprise as unit of structural organization of entrepreneurial activity. Thus, institutional possibilities of classic institution and neoinstitution were insufficient for development of management methodology of logistic expenses of enterprise. A question consists in contradiction between a manner and matter of economic activity in the historical and chronological evolutional understanding results in changing of both institutional form and structural maintenance of enterprise. In-process in postneoinstitutional axiomatic theory of economic analysis the concept of local chain of financially-productive relations, concept of it technological and commercial expansion, concept of simple and branched global chain of financially-productive relations appears. By means of concept of reviving that is placing of the logistic systems in global chains the fundamental concept of the

  3. Enhanced sonocatalysis of textile wastewater using bentonite-supported ZnO nanoparticles: Response surface methodological approach.

    Science.gov (United States)

    Darvishi Cheshmeh Soltani, Reza; Jorfi, Sahand; Safari, Mahdi; Rajaei, Mohammad-Sadegh

    2016-09-01

    The scope of this study was the use of bentonite as the carrier of ZnO nanoparticles for enhancing the sonocatalytic decolorization of Basic Red 46 (BR46) in the aqueous phase. The results demonstrated the higher sonocatalytic activity of bentonite-supported ZnO nanoparticles (BSZNs) in comparison with the suspended ZnO nanoparticles (SZNs). The particle size of BSZNs (5-40 nm) was lower than that of SZNs (20-120 nm). Due to the immobilization of ZnO nanoparticles, a specific surface area of 80.6 m(2)/g was obtained for the BSZNs, which was higher than the specific surface area of the raw bentonite (42.2 m(2)/g). Optimization of the process via response surface methodology (RSM) based on central composite design (CCD) showed the maximum sonocatalytic decolorization efficiency (%) of 89.92% in which the initial dye concentration, the ZnO/bentonite ratio, the sonocatalyst dosage, and the initial pH were 6 mg/L, 0.3, 2.5 g/L and 9, respectively. The byproducts generated during the sonocatalysis of BR46 over BSZNs were identified using gas chromatography-mass spectrometry (GC-MS) analysis. From an application viewpoint, the sonocatalysis of real textile wastewater resulted in a COD removal efficiency (%) of about 44% within a reaction time of 150 min.

  4. How to assess the external validity and model validity of therapeutic trials: a conceptual approach to systematic review methodology.

    Science.gov (United States)

    Khorsan, Raheleh; Crawford, Cindy

    2014-01-01

    Background. Evidence rankings do not consider equally internal (IV), external (EV), and model validity (MV) for clinical studies including complementary and alternative medicine/integrative medicine (CAM/IM) research. This paper describe this model and offers an EV assessment tool (EVAT©) for weighing studies according to EV and MV in addition to IV. Methods. An abbreviated systematic review methodology was employed to search, assemble, and evaluate the literature that has been published on EV/MV criteria. Standard databases were searched for keywords relating to EV, MV, and bias-scoring from inception to Jan 2013. Tools identified and concepts described were pooled to assemble a robust tool for evaluating these quality criteria. Results. This study assembled a streamlined, objective tool to incorporate for the evaluation of quality of EV/MV research that is more sensitive to CAM/IM research. Conclusion. Improved reporting on EV can help produce and provide information that will help guide policy makers, public health researchers, and other scientists in their selection, development, and improvement in their research-tested intervention. Overall, clinical studies with high EV have the potential to provide the most useful information about "real-world" consequences of health interventions. It is hoped that this novel tool which considers IV, EV, and MV on equal footing will better guide clinical decision making.

  5. Resolving the neural dynamics of visual and auditory scene processing in the human brain: a methodological approach

    Science.gov (United States)

    Teng, Santani

    2017-01-01

    In natural environments, visual and auditory stimulation elicit responses across a large set of brain regions in a fraction of a second, yielding representations of the multimodal scene and its properties. The rapid and complex neural dynamics underlying visual and auditory information processing pose major challenges to human cognitive neuroscience. Brain signals measured non-invasively are inherently noisy, the format of neural representations is unknown, and transformations between representations are complex and often nonlinear. Further, no single non-invasive brain measurement technique provides a spatio-temporally integrated view. In this opinion piece, we argue that progress can be made by a concerted effort based on three pillars of recent methodological development: (i) sensitive analysis techniques such as decoding and cross-classification, (ii) complex computational modelling using models such as deep neural networks, and (iii) integration across imaging methods (magnetoencephalography/electroencephalography, functional magnetic resonance imaging) and models, e.g. using representational similarity analysis. We showcase two recent efforts that have been undertaken in this spirit and provide novel results about visual and auditory scene analysis. Finally, we discuss the limits of this perspective and sketch a concrete roadmap for future research. This article is part of the themed issue ‘Auditory and visual scene analysis’. PMID:28044019

  6. Biosorption and biodegradation of Acid Orange 7 by Enterococcus faecalis strain ZL: optimization by response surface methodological approach.

    Science.gov (United States)

    Lim, Chi Kim; Bay, Hui Han; Aris, Azmi; Abdul Majid, Zaiton; Ibrahim, Zaharah

    2013-07-01

    Reactive dyes account for one of the major sources of dye wastes in textile effluent. In this study, decolorization of the monoazo dye, Acid Orange 7 (AO7) by the Enterococcus faecalis strain ZL that isolated from a palm oil mill effluent treatment plant has been investigated. Decolorization efficiency of azo dye is greatly affected by the types of nutrients and the size of inoculum used. In this work, one-factor-at-a-time (method and response surface methodology (RSM) was applied to optimize these operational factors and also to study the combined interaction between them. Analysis of AO7 decolorization was done using Fourier transform infrared (FTIR) spectroscopy, desorption study, UV-Vis spectral analysis, field emission scanning electron microscopy (FESEM), and high performance liquid chromatography (HPLC). The optimum condition via RSM for the color removal of AO7 was found to be as follows: yeast extract, 0.1% w/v, glycerol concentration of 0.1% v/v, and inoculum density of 2.5% v/v at initial dye concentration of 100 mg/L at 37 °C. Decolorization efficiency of 98% was achieved in only 5 h. The kinetic of AO7 decolorization was found to be first order with respect to dye concentration with a k value of 0.87/h. FTIR, desorption study, UV-Vis spectral analysis, FESEM, and HPLC findings indicated that the decolorization of AO7 was mainly due to the biosorption as well as biodegradation of the bacterial cells. In addition, HPLC analyses also showed the formation of sulfanilic acid as a possible degradation product of AO7 under facultative anaerobic condition. This study explored the ability of E. faecalis strain ZL in decolorizing AO7 by biosorption as well as biodegradation process.

  7. Rosiglitazone: can meta-analysis accurately estimate excess cardiovascular risk given the available data? Re-analysis of randomized trials using various methodologic approaches

    Directory of Open Access Journals (Sweden)

    Friedrich Jan O

    2009-01-01

    Full Text Available Abstract Background A recent and provocative meta-analysis, based on few outcome events, suggested that rosiglitazone increased cardiovascular mortality and myocardial infarction. However, results of meta-analyses of trials with sparse events, often performed when examining uncommon adverse effects due to common therapies, can vary substantially depending on methodologic decisions. The objective of this study was to assess the robustness of the rosiglitazone results by using alternative reasonable methodologic approaches and by analyzing additional related outcomes. Findings In duplicate and independently, we abstracted all myocardial and cerebrovascular ischemic events from all randomized controlled trials listed on the manufacturer's web site meeting inclusion criteria of the original meta-analysis (at least 24 weeks of rosiglitazone exposure in the intervention group and any control group without rosiglitazone. We performed meta-analyses of these data under different methodologic conditions. An unconfounded comparison that includes only trials (or arms of trials in which medications apart from rosiglitazone are identical suggests higher risks than previously reported, making even the risk of cardiovascular death statistically significant. Alternatively, meta-analysis that includes all trials comparing a treatment arm receiving rosiglitazone to any control arm without rosiglitazone (as in the original meta-analysis but also including trials with no events in both the rosiglitazone and control arms (not incorporated in the original meta-analysis, shows adverse but non-statistically significant effects of rosiglitazone on myocardial infarction and cardiovascular mortality. Rosiglitazone appears to have inconsistent effects on a wider range of cardiovascular outcomes. It increases the risk of a broad range of myocardial ischemic events (not just myocardial infarction. However, its effect on cerebrovascular ischemic events suggests benefit

  8. A methodological approach to the analysis of egocentric social networks in public health research: a practical example.

    Science.gov (United States)

    Djomba, Janet Klara; Zaletel-Kragelj, Lijana

    2016-12-01

    Research on social networks in public health focuses on how social structures and relationships influence health and health-related behaviour. While the sociocentric approach is used to study complete social networks, the egocentric approach is gaining popularity because of its focus on individuals, groups and communities. One of the participants of the healthy lifestyle health education workshop 'I'm moving', included in the study of social support for exercise was randomly selected. The participant was denoted as the ego and members of her/his social network as the alteri. Data were collected by personal interviews using a self-made questionnaire. Numerical methods and computer programmes for the analysis of social networks were used for the demonstration of analysis. The size, composition and structure of the egocentric social network were obtained by a numerical analysis. The analysis of composition included homophily and homogeneity. Moreover, the analysis of the structure included the degree of the egocentric network, the strength of the ego-alter ties and the average strength of ties. Visualisation of the network was performed by three freely available computer programmes, namely: Egonet.QF, E-net and Pajek. The computer programmes were described and compared by their usefulness. Both numerical analysis and visualisation have their benefits. The decision what approach to use is depending on the purpose of the social network analysis. While the numerical analysis can be used in large-scale population-based studies, visualisation of personal networks can help health professionals at creating, performing and evaluation of preventive programmes, especially if focused on behaviour change.

  9. Methodological approaches to developing and establishing the body of evidence on post-marketing Chinese medicine safety.

    Science.gov (United States)

    Liao, Xing; Robinson, Nicola

    2013-07-01

    Evidence based medicine demands the highest form of scientific evidence to demonstrate the efficacy and clinical effectiveness for any therapeutic intervention in order to provide best care. It is however accepted that in the absence of scientific evidence, personal experience and expert opinion together with professional judgement are critical. Obtaining evidence for drug safety, postmarketing surveillance (PMS) has focussed on follow up of observational cohorts exposed to a particular drug in order to estimate the incidence of adverse drug reactions (ADRs). Evidence on PMS of Chinese herbal products is still limited, in particular for herbal injections. The aim of this article is to suggest a new model of ascertaining the safety of Chinese medicine using a more comprehensive approach for collecting data. To collect safety data on the Chinese herbal injection, Kudiezi, a mixed methods approach is proposed using 18 hospital information systems to detect ADRs in order to prospectively observe 30,000 patients over 3 years. Evidence will also be collected using a questionnaire survey and through a sample of semi structured interviews. This information based on the expert opinion and the experience of clinicians will produce additional data on the frequency and types of side effects in clinical practice. Furthermore semi structured interviews with a random sample of patients receiving the injection will be carried out to ascertain any potential side effects missed. It is hoped that this comprehensive approach to data collection will accumulate wider evidence based on individual traditional Chinese medicine care and treatment and provide important feedback to the national data collection system to ensure completeness of ADR data recording, monitoring and any potential wider effects through developing improved ADR guidelines.

  10. A multiscale approach to blast neurotrauma modeling:Part II: Methodology for inducing blast injury to in vitro models

    Directory of Open Access Journals (Sweden)

    Gwen B. Effgen

    2012-02-01

    Full Text Available Due to the prominent role of improvised explosive devices (IEDs in wounding patterns of U.S. war-fighters in Iraq and Afghanistan, blast injury has risen to a new level of importance and is recognized to be a major cause of injuries to the brain. However, an injury risk-function for microscopic, macroscopic, behavioral, and neurological deficits has yet to be defined. While operational blast injuries can be very complex and thus difficult to analyze, a simplified blast injury model would facilitate studies correlating biological outcomes with blast biomechanics to define tolerance criteria. Blast-induced traumatic brain injury (bTBI results from the translation of a shock wave in air, such as that produced by an IED, into a pressure wave within the skull-brain complex. Our blast injury methodology recapitulates this phenomenon in vitro, allowing for control of the injury biomechanics via a compressed-gas shock tube used in conjunction with a custom-designed, fluid-filled receiver that contains the living culture. The receiver converts the air shock wave into a fast-rising pressure transient with minimal reflections, mimicking the intracranial pressure history in blast. We have developed an organotypic hippocampal slice culture model that exhibits cell death when exposed to a 530  17.7 kPa peak overpressure with a 1.026 ± 0.017 ms duration and 190 ± 10.7 kPa-ms impulse in-air. We have also injured a simplified in vitro model of the blood-brain barrier, which exhibits disrupted integrity immediately following exposure to 581  10.0 kPa peak overpressure with a 1.067 ms ± 0.006 ms duration and 222 ± 6.9 kPa-ms impulse in-air. To better prevent and treat bTBI, both the initiating biomechanics and the ensuing pathobiology must be understood in greater detail. A well-characterized, in vitro model of bTBI, in conjunction with animal models, will be a powerful tool for developing strategies to mitigate the risks of bTBI.

  11. PROPUESTA METODOLÓGICA PARA EL ANÁLISIS DE LOS EVENTOS CENTINELA. Methodological approach for sentry events analysis

    Directory of Open Access Journals (Sweden)

    Jorge Martín Rodríguez

    2007-06-01

    Full Text Available Las entidades de vigilancia, inspección y control de orden nacional, departamental y local están solicitando a las aseguradoras (ARS, EPS, entidades adaptadas, ESEs e instituciones prestadoras de salud (IPS, basados en la normatividad vigente del Sistema General de Seguridad Social en Salud, la supervisión, asesoría técnica y garantía de la calidad ante la ocurrencia de los eventos centinelas para contribuir al control y disminución de su incidencia, interviniendo los factores de riesgo asociados a la prestación de los servicios de salud en la población a cargo (cotizantes y beneficiarios en el régimen contributivo, asignados en el régimen subsidiado o en la población pobre no asegurada. Esta es una propuesta metodológica que orienta la definición e identificación de los eventos centinela e igualmente facilita la identificación de los factores asociados a su ocurrencia, para orientar acciones e intervenciones, que deben realizar las IPS con base a los problemas caracterizados encontrados.National organizations departmental and local of monitoring, inspection, facilities are demanding to the Insurance company (ARS, EPS, the adapted organizations, ESEs and others companies of Health, based on the effective norms of the General System of Social Security in Health, the supervision, technical consultant’s office and guarantee of the quality of the Sentinel Events to contribute to the control and diminution of their occurrence, intervening the associated factors of risk to the Benefit of the Health Services in the population to position (Assured in the Contributing Regime, assigned in the Subsidized Regime or poor people no assured. This is methodological proposal that allows defining and to identify the Sentinel Events, to determine the associated factors to his presence and it orients in the actions and interventions that must make the Health Services with base to the weaknesses or failures found.

  12. A methodological approach to screen diverse cheese-related bacteria for their ability to produce aroma compounds.

    Science.gov (United States)

    Pogačić, Tomislav; Maillard, Marie-Bernadette; Leclerc, Aurélie; Hervé, Christophe; Chuat, Victoria; Yee, Alyson L; Valence, Florence; Thierry, Anne

    2015-04-01

    Microorganisms play an important role in the development of cheese flavor. The aim of this study was to develop an approach to facilitate screening of various cheese-related bacteria for their ability to produce aroma compounds. We combined i) curd-based slurry medium incubated under conditions mimicking cheese manufacturing and ripening, ii) powerful method of extraction of volatiles, headspace trap, coupled to gas chromatography-mass spectrometry (HS-trap-GC-MS), and iii) metabolomics-based method of data processing using the XCMS package of R software and multivariate analysis. This approach was applied to eleven species: five lactic acid bacteria (Leuconostoc lactis, Lactobacillus sakei, Lactobacillus paracasei, Lactobacillus fermentum, and Lactobacillus helveticus), four actinobacteria (Brachybacterium articum, Brachybacterium tyrofermentans, Brevibacterium aurantiacum, and Microbacterium gubbeenense), Propionibacterium freudenreichii, and Hafnia alvei. All the strains grew, with maximal populations ranging from 7.4 to 9.2 log (CFU/mL). In total, 52 volatile aroma compounds were identified, of which 49 varied significantly in abundance between bacteria. Principal component analysis of volatile profiles differentiated species by their ability to produce ethyl esters (associated with Brachybacteria), sulfur compounds and branched-chain alcohols (H. alvei), branched-chain acids (H. alvei, P. freudenreichii and L. paracasei), diacetyl and related carbonyl compounds (M. gubbeenense and L. paracasei), among others.

  13. Cumulative Risk Assessment: An Overview of Methodological Approaches for Evaluating Combined Health Effects from Exposure to Multiple Environmental Stressors

    Science.gov (United States)

    Sexton, Ken

    2012-01-01

    Systematic evaluation of cumulative health risks from the combined effects of multiple environmental stressors is becoming a vital component of risk-based decisions aimed at protecting human populations and communities. This article briefly examines the historical development of cumulative risk assessment as an analytical tool, and discusses current approaches for evaluating cumulative health effects from exposure to both chemical mixtures and combinations of chemical and nonchemical stressors. A comparison of stressor-based and effects-based assessment methods is presented, and the potential value of focusing on viable risk management options to limit the scope of cumulative evaluations is discussed. The ultimate goal of cumulative risk assessment is to provide answers to decision-relevant questions based on organized scientific analysis; even if the answers, at least for the time being, are inexact and uncertain. PMID:22470298

  14. Ultrasound-guided diagnostic breast biopsy methodology: retrospective comparison of the 8-gauge vacuum-assisted biopsy approach versus the spring-loaded 14-gauge core biopsy approach

    Science.gov (United States)

    2011-01-01

    Background Ultrasound-guided diagnostic breast biopsy technology represents the current standard of care for the evaluation of indeterminate and suspicious lesions seen on diagnostic breast ultrasound. Yet, there remains much debate as to which particular method of ultrasound-guided diagnostic breast biopsy provides the most accurate and optimal diagnostic information. The aim of the current study was to compare and contrast the 8-gauge vacuum-assisted biopsy approach and the spring-loaded 14-gauge core biopsy approach. Methods A retrospective analysis was done of all ultrasound-guided diagnostic breast biopsy procedures performed by either the 8-gauge vacuum-assisted biopsy approach or the spring-loaded 14-gauge core biopsy approach by a single surgeon from July 2001 through June 2009. Results Among 1443 ultrasound-guided diagnostic breast biopsy procedures performed, 724 (50.2%) were by the 8-gauge vacuum-assisted biopsy technique and 719 (49.8%) were by the spring-loaded 14-gauge core biopsy technique. The total number of false negative cases (i.e., benign findings instead of invasive breast carcinoma) was significantly greater (P = 0.008) in the spring-loaded 14-gauge core biopsy group (8/681, 1.2%) as compared to in the 8-gauge vacuum-assisted biopsy group (0/652, 0%), with an overall false negative rate of 2.1% (8/386) for the spring-loaded 14-gauge core biopsy group as compared to 0% (0/148) for the 8-gauge vacuum-assisted biopsy group. Significantly more (P biopsy group (81/719, 11.3%) than in the 8-gauge vacuum-assisted biopsy group (18/724, 2.5%) were recommended for further diagnostic surgical removal of additional tissue from the same anatomical site of the affected breast in an immediate fashion for indeterminate/inconclusive findings seen on the original ultrasound-guided diagnostic breast biopsy procedure. Significantly more (P biopsy group (54/719, 7.5%) than in the 8-gauge vacuum-assisted biopsy group (9/724, 1.2%) personally requested further

  15. The analysis of phytoliths and its role in teh study of the consumption of vegetal resources in prehistory: the bases for a materialist methodological approach

    Directory of Open Access Journals (Sweden)

    Zurro, Débora

    2006-12-01

    Full Text Available This paper is strucured in two parts. The first one offers an introduction to phytolith analysis exploring the characteristics of these particles, the laboratory procedures in use, the current state of research and the informative potential they can offer to archaeology. The second part proposes the basis of a methodological approach for applying this technique to archaeology. This methodology uses historical materialism and is based on the Marxist concept of value, the analysis of the processes of labour and the categorisation of phytolith assemblages based on the selection of vegetal materials.

    La primera parte de este trabajo presenta una introducción al análisis de fitolitos. En ella se especifican cuestiones tales como las características de estas partículas, las bases de su tratamiento en laboratorio, el estado actual de la investigación o su potencial informativo para nuestra disciplina. En la segunda parte se establecen las bases de una propuesta metodológica (actualmente en desarrollo para la aplicación de esta técnica en arqueología. Dicha propuesta parte del materialismo histórico y se basa en el concepto marxista de valor objetivo, el análisis de los procesos de trabajo y la categorización, en base a la selección de las materias vegetales, de los conjuntos fitolitológicos.

  16. Technical measures without enforcement tools: is there any sense? A methodological approach for the estimation of passive net length in small scale fisheries

    Directory of Open Access Journals (Sweden)

    A. LUCCHETTI

    2014-09-01

    Full Text Available Passive nets are currently among the most important fishing gears largely used along the Mediterranean coasts by the small scale fisheries sector. The fishing effort exerted by this sector is strongly correlated with net dimensions. Therefore, the use of passive nets is worldwide managed by defining net length and net drop. The EC Reg. 1967/2006 reports that the length of bottom-set and drifting nets may be also defined considering their weight or volume; however, no practical suggestions for fisheries inspectors are yet available. Consequently,  even if such technical measures are reasonable from a theoretical viewpoint, they are hardly suitable as a management tool, due to the difficulties in harbour control. The overall objective of this paper is to provide a quick methodological approach for the gross estimation of passive net length (by net type on the basis of net volume. The final goal is to support fisheries managers with suitable advice for enforcement and control purposes. The results obtained are important for the management of the fishing effort exerted by small scale fisheries. The methodology developed in this study should be considered as a first attempt to tackle the tangled problem of net length estimation that can be easily applied in other fisheries and areas in order to improve the precision of the models developed herein.

  17. Trends in the theoretical and research methodological approaches applied in doctoral studies in information and knowledge management: an exploration of ten years of research in South Africa

    Directory of Open Access Journals (Sweden)

    M. A. Mearns

    2008-01-01

    Full Text Available The past ten years have seen the field of information and knowledge management develop and implement new and improved technologies. Because of the ease with which information is exchanged the contribution to information overload has increased exponentially and the need for information and knowledge management is more real than ever before. Research in itself is a science of knowledge creation that continuously evolves in line with newly developed theories and research methodologies. An investigation of the theories and research methodologies that doctoral theses, completed in South Africa, ascribed to over the past ten years were conducted. Search strings containing 'information management', 'knowledge management' and 'information and knowledge management' were searched within citation, abstract and subject fields. A sample of 30 theses from a possible 47 in the relevant population was identified. Qualitative and mixed methods research design was favoured, making use of case studies and surveys, but paying little attention to theoretical approaches or paradigms. The boundaries between disciplines are continuously re-defined, new disciplines evolve and traditional disciplines suffer under the pressures of changing problems of the world. The importance of research in the field of information and knowledge management being grounded in the most recent scientific thought is emphasized.

  18. Technical measures without enforcement tools: is there any sense? A methodological approach for the estimation of passive net length in small scale fisheries

    Directory of Open Access Journals (Sweden)

    A. LUCCHETTI

    2015-01-01

    Full Text Available Passive nets are currently among the most important fishing gears largely used along the Mediterranean coasts by the small scale fisheries sector. The fishing effort exerted by this sector is strongly correlated with net dimensions. Therefore, the use of passive nets is worldwide managed by defining net length and net drop. The EC Reg. 1967/2006 reports that the length of bottom-set and drifting nets may be also defined considering their weight or volume; however, no practical suggestions for fisheries inspectors are yet available. Consequently,  even if such technical measures are reasonable from a theoretical viewpoint, they are hardly suitable as a management tool, due to the difficulties in harbour control. The overall objective of this paper is to provide a quick methodological approach for the gross estimation of passive net length (by net type on the basis of net volume. The final goal is to support fisheries managers with suitable advice for enforcement and control purposes. The results obtained are important for the management of the fishing effort exerted by small scale fisheries. The methodology developed in this study should be considered as a first attempt to tackle the tangled problem of net length estimation that can be easily applied in other fisheries and areas in order to improve the precision of the models developed herein.

  19. A new formulation for air-blast fluid-structure interaction using an immersed approach. Part I: basic methodology and FEM-based simulations

    Science.gov (United States)

    Bazilevs, Y.; Kamran, K.; Moutsanidis, G.; Benson, D. J.; Oñate, E.

    2017-03-01

    In this two-part paper we begin the development of a new class of methods for modeling fluid-structure interaction (FSI) phenomena for air blast. We aim to develop accurate, robust, and practical computational methodology, which is capable of modeling the dynamics of air blast coupled with the structure response, where the latter involves large, inelastic deformations and disintegration into fragments. An immersed approach is adopted, which leads to an a-priori monolithic FSI formulation with intrinsic contact detection between solid objects, and without formal restrictions on the solid motions. In Part I of this paper, the core air-blast FSI methodology suitable for a variety of discretizations is presented and tested using standard finite elements. Part II of this paper focuses on a particular instantiation of the proposed framework, which couples isogeometric analysis (IGA) based on non-uniform rational B-splines and a reproducing-kernel particle method (RKPM), which is a Meshfree technique. The combination of IGA and RKPM is felt to be particularly attractive for the problem class of interest due to the higher-order accuracy and smoothness of both discretizations, and relative simplicity of RKPM in handling fragmentation scenarios. A collection of mostly 2D numerical examples is presented in each of the parts to illustrate the good performance of the proposed air-blast FSI framework.

  20. Trends in the theoretical and research methodological approaches applied in doctoral studies in information and knowledge management: an exploration of ten years of research in South Africa

    Directory of Open Access Journals (Sweden)

    M. A. Mearns

    2008-01-01

    Full Text Available The past ten years have seen the field of information and knowledge management develop and implement new and improved technologies. Because of the ease with which information is exchanged the contribution to information overload has increased exponentially and the need for information and knowledge management is more real than ever before. Research in itself is a science of knowledge creation that continuously evolves in line with newly developed theories and research methodologies. An investigation of the theories and research methodologies that doctoral theses, completed in South Africa, ascribed to over the past ten years were conducted. Search strings containing 'information management', 'knowledge management' and 'information and knowledge management' were searched within citation, abstract and subject fields. A sample of 30 theses from a possible 47 in the relevant population was identified. Qualitative and mixed methods research design was favoured, making use of case studies and surveys, but paying little attention to theoretical approaches or paradigms. The boundaries between disciplines are continuously re-defined, new disciplines evolve and traditional disciplines suffer under the pressures of changing problems of the world. The importance of research in the field of information and knowledge management being grounded in the most recent scientific thought is emphasized.

  1. Ultrasound-guided diagnostic breast biopsy methodology: retrospective comparison of the 8-gauge vacuum-assisted biopsy approach versus the spring-loaded 14-gauge core biopsy approach

    OpenAIRE

    Jimenez Rafael E; Povoski Stephen P; Wang Wenle P

    2011-01-01

    Abstract Background Ultrasound-guided diagnostic breast biopsy technology represents the current standard of care for the evaluation of indeterminate and suspicious lesions seen on diagnostic breast ultrasound. Yet, there remains much debate as to which particular method of ultrasound-guided diagnostic breast biopsy provides the most accurate and optimal diagnostic information. The aim of the current study was to compare and contrast the 8-gauge vacuum-assisted biopsy approach and the spring-...

  2. The network adjustment aimed for the campaigned gravity survey using a Bayesian approach: methodology and model test

    Science.gov (United States)

    Chen, Shi; Liao, Xu; Ma, Hongsheng; Zhou, Longquan; Wang, Xingzhou; Zhuang, Jiancang

    2017-04-01

    The relative gravimeter, which generally uses zero-length springs as the gravity senor, is still as the first choice in the field of terrestrial gravity measurement because of its efficiency and low-cost. Because the drift rate of instrument can be changed with the time and meter, it is necessary for estimating the drift rate to back to the base or known gravity value stations for repeated measurement at regular hour's interval during the practical survey. However, the campaigned gravity survey for the large-scale region, which the distance of stations is far away from serval or tens kilometers, the frequent back to close measurement will highly reduce the gravity survey efficiency and extremely time-consuming. In this paper, we proposed a new gravity data adjustment method for estimating the meter drift by means of Bayesian statistical interference. In our approach, we assumed the change of drift rate is a smooth function depend on the time-lapse. The trade-off parameters were be used to control the fitting residuals. We employed the Akaike's Bayesian Information Criterion (ABIC) for the estimated these trade-off parameters. The comparison and analysis of simulated data between the classical and Bayesian adjustment show that our method is robust and has self-adaptive ability for facing to the unregularly non-linear meter drift. At last, we used this novel approach to process the realistic campaigned gravity data at the North China. Our adjustment method is suitable to recover the time-varied drift rate function of each meter, and also to detect the meter abnormal drift during the gravity survey. We also defined an alternative error estimation for the inversed gravity value at the each station on the basis of the marginal distribution theory. Acknowledgment: This research is supported by Science Foundation Institute of Geophysics, CEA from the Ministry of Science and Technology of China (Nos. DQJB16A05; DQJB16B07), China National Special Fund for Earthquake

  3. Methodological approaches for the prospecting of sites of extensive soil contamination in loose sediments; Methodische Ansaetze zur Erkundung grossflaechiger Bodenkontamination in Lockersedimenten

    Energy Technology Data Exchange (ETDEWEB)

    Grunewald, K. [Technische Univ. Dresden (Germany). Inst. fuer Geographie; Barsch, H. [WIB GmbH, Berlin (Germany); Bechmann, W. [Univ. Potsdam (Germany). Inst. fuer Physikalische und Theoretische Chemie; Bukowsky, H. [Univ. Potsdam (Germany). Inst. fuer Anorganische Chemie

    1995-12-01

    Cases of extensive soil contamination pose serious problems in many areas. They call for risk assessments, redevelopment proposals, and concepts of use. While small abandoned sites can be more easily spatially delimited, the prospecting of large contaminated areas requires a special approach because of the dimensions involved.- The paper describes methodological experience gained during practical, inter-disciplinary investigations in loose sediments of Brandenburg. The method, which consists of an inventory, the structuring of data, a report on and evaluation of results and action recommendations, is described. (orig.) [Deutsch] Grossflaechige Bodenkontaminationen stellen in vielen Gebieten ernstzunehmende Probleme dar. Fuer diese muessen Gefaehrdungsabschaetzungen, Sanierungsvorschlaege und Nutzungskonzeptionen erarbeitet werden. Gegenueber kleinflaechigen und raeumlich leichter eingrenzbaren Altlasten ist fuer die Erkundung grossflaechig kontaminierter Gebiete auf Grund ihrer Dimensionen ein spezieller Ansatz notwendig. Es werden methodische Erfahrungen vorgestellt, die bei praktischen, interdisziplinaeren Untersuchungen in Lockersedimenten Brandenburgs erprobt wurden. Die Vorgehensweise, bestehend aus Bestandsaufnahme, Datenstrukturierung, Darstellung und Bewertung der Ergebnisse sowie Handlungsempfehlungen, wird erlaeutert. (orig.)

  4. Approach toward enhancement of halophilic protease production by Halobacterium sp. strain LBU50301 using statistical design response surface methodology

    Directory of Open Access Journals (Sweden)

    Julalak Chuprom

    2016-06-01

    Full Text Available A new potent halophilic protease producer, Halobacterium sp. strain LBU50301 was isolated from salt-fermented fish samples (budu and identified by phenotypic analysis, and 16S rDNA gene sequencing. Thereafter, sequential statistical strategy was used to optimize halophilic protease production from Halobacterium sp. strain LBU50301 by shake-flask fermentation. The classical one-factor-at-a-time (OFAT approach determined gelatin was the best nitrogen source. Based on Plackett–Burman (PB experimental design; gelatin, MgSO4·7H2O, NaCl and pH significantly influenced the halophilic protease production. Central composite design (CCD determined the optimum level of medium components. Subsequently, an 8.78-fold increase in corresponding halophilic protease yield (156.22 U/mL was obtained, compared with that produced in the original medium (17.80 U/mL. Validation experiments proved the adequacy and accuracy of model, and the results showed the predicted value agreed well with the experimental values. An overall 13-fold increase in halophilic protease yield was achieved using a 3 L laboratory fermenter and optimized medium (231.33 U/mL.

  5. Can we use modelling methodologies to assess airborne benzo[a]pyrene from biomonitors? A comprehensive evaluation approach

    Directory of Open Access Journals (Sweden)

    N. Ratola

    2015-09-01

    Full Text Available Biomonitoring data available on levels of atmospheric polycyclic aromatic hydrocarbons (PAHs in pine needles from the Iberian Peninsula was used to estimate air concentrations of benzo[a]pyrene (BaP and, at the same time, fuelled the comparison with chemistry transport model representations. Simulations with the modelling system WRF + CHIMERE were validated against data from the European Monitoring and Evaluation Programme (EMEP air sampling network and using modelled atmospheric concentrations as a consistent reference in order to compare the performance of vegetation-to-air estimating methods. A spatial and temporal resolution of 9 km and 1 h was implemented. The field-based database relied on a pine needles sampling scheme comprising 33 sites in Portugal and 37 sites in Spain complemented with the BaP measurements available from the EMEP sites. The ability of pine needles to act as biomonitoring markers for the atmospheric concentrations of BaP was estimated converting the levels obtained in pine needles into air concentrations by six different approaches, one of them presenting realistic concentrations when compared to the modelled atmospheric values. The justification for this study is the gaps still existing in the knowledge of the life cycles of semi-volatile organic compounds (SVOCs, particularly the partition processes between air and vegetation. The strategy followed in this work allows the definition of the transport patterns (e.g. dispersion established by the model for atmospheric concentrations and the estimated values in vegetation.

  6. DESIGNING A MODERN LABORATORY FOR URBAN COMBAT TRAINING (L4UCT. A PROJECT MANAGEMENT METHODOLOGY BASED APPROACH

    Directory of Open Access Journals (Sweden)

    Dorel BADEA

    2015-04-01

    Full Text Available This paper presents the essential coordinates of the project concerning the achievement of feasible versions in terms of their design and functions of a laboratory for urban operations for cadets, with high potential for implementation in military higher education institutions. Data to identify the optimal correlation (in terms of technical, system and operational views between game and simulation, applicable in the military field, based on the use of available airsoft weapons and specialized software existing on the specialized market for military and / or civilian use are envisaged. Our approach for this project maintains the common areas (resources, rules, actors in the professional civil literature and the types of simulation defined in military documents: real simulation (it implies real people operating real systems, virtual simulation (it implies real people operating simulated systems and constructive simulation (models and simulations which imply simulated people operating simulated systems, with real people setting the premises but not determining in any way the outcome of the simulation.

  7. Tourism Methodologies

    DEFF Research Database (Denmark)

    This volume offers methodological discussions within the multidisciplinary field of tourism and shows how tourism researchers develop and apply new tourism methodologies. The book is presented as an anthology, giving voice to many diverse researchers who reflect on tourism methodology in different...... in interview and field work situations, and how do we engage with the performative aspects of tourism as a field of study? The book acknowledges that research is also performance and that it constitutes an aspect of intervention in the situations and contexts it is trying to explore. This is an issue dealt...

  8. Disease maps as context for community mapping: a methodological approach for linking confidential health information with local geographical knowledge for community health research.

    Science.gov (United States)

    Beyer, Kirsten M M; Comstock, Sara; Seagren, Renea

    2010-12-01

    Health is increasingly understood as a product of multiple levels of influence, from individual biological and behavioral influences to community and societal level contextual influences. In understanding these contextual influences, community health researchers have increasingly employed both geographic methodologies, including Geographic Information Systems (GIS), and community participatory approaches. However, despite growing interest in the role for community participation and local knowledge in community health investigations, and the use of geographical methods and datasets in characterizing community environments, there exist few examples of research projects that incorporate both geographical and participatory approaches in addressing health questions. This is likely due in part to concerns and restrictions regarding community access to confidential health data. In order to overcome this barrier, we present a method for linking confidential, geocoded health information with community-generated experiential geographical information in a GIS environment. We use sophisticated disease mapping methodologies to create continuously defined maps of colorectal cancer in Iowa, then incorporate these layers in an open source GIS application as the context for a participatory community mapping exercise with participants from a rural Iowa town. Our method allows participants to interact directly with health information at a fine geographical scale, facilitating hypothesis generation regarding contextual influences on health, while simultaneously protecting data confidentiality. Participants are able to use their local, geographical knowledge to generate hypotheses about factors influencing colorectal cancer risk in the community and opportunities for risk reduction. This work opens the door for future efforts to integrate empirical epidemiological data with community generated experiential information to inform community health research and practice.

  9. A general analysis of calibrated BOLD methodology for measuring CMRO2 responses: comparison of a new approach with existing methods.

    Science.gov (United States)

    Blockley, Nicholas P; Griffeth, Valerie E M; Buxton, Richard B

    2012-03-01

    The amplitude of the BOLD response to a stimulus is not only determined by changes in cerebral blood flow (CBF) and oxygen metabolism (CMRO(2)), but also by baseline physiological parameters such as haematocrit, oxygen extraction fraction (OEF) and blood volume. The calibrated BOLD approach aims to account for this physiological variation by performing an additional calibration scan. This calibration typically consists of a hypercapnia or hyperoxia respiratory challenge, although we propose that a measurement of the reversible transverse relaxation rate, R(2)', might also be used. A detailed model of the BOLD effect was used to simulate each of the calibration experiments, as well as the activation experiment, whilst varying a number of physiological parameters associated with the baseline state and response to activation. The effectiveness of the different calibration methods was considered by testing whether the BOLD response to activation scaled by the calibration parameter combined with the measured CBF provides sufficient information to reliably distinguish different levels of CMRO(2) response despite underlying physiological variability. In addition the effect of inaccuracies in the underlying assumptions of each technique were tested, e.g. isometabolism during hypercapnia. The three primary findings of the study were: 1) The new calibration method based on R(2)' worked reasonably well, although not as well as the ideal hypercapnia method; 2) The hyperoxia calibration method was significantly worse because baseline haematocrit and OEF must be assumed, and these physiological parameters have a significant effect on the measurements; and 3) the venous blood volume change with activation is an important confounding variable for all of the methods, with the hypercapnia method being the most robust when this is uncertain.

  10. Connecting the Disconnected: Social Work and Social Network Analysis. A Methodological Approach to Identifying Network Peer Leaders

    Directory of Open Access Journals (Sweden)

    del Fresno García, Miguel

    2015-02-01

    Full Text Available Social network theory and analysis (SNA offers a useful conceptual framework and a robust set of methods for understanding, analysing, and representing the pattern of social interactions that surround individuals forming an overall network of ties. SNA provides both insights and applications regarding relational structures that may be consequential for individual and collective agency. Despite the fact that both SNA and social work focus on relationships and behaviour, and that each discipline could substantively inform the other, there remains a significant lack of intersection between the two disciplines. In response to this gap, SNA applied to social work can provide additional ways to both diagnose and intervene behaviourally through the following approaches: a by identifying key players in promoting the dissemination of behavioral changes in networks; b by segmenting and identifying groups, cliques and communities; c by supporting behavioural change through social ties surrounding the individual; and d by aligning and applying specific interventions that draw on mutually interactive processes in terms of individual influences on networks, as well as network influences on individuals. SNA provides social work with an additional lens and set of tools based on the constellation of interactions surrounding individuals, families, groups or communities that supports understanding, diagnosis, and intervention.La Teoría y Análisis de Redes Sociales (SNA ofrece un conjunto de métodos de análisis de las interacciones sociales de los seres humanos, que permiten de forma específica investigar las estructuras relacionales y la representación de éstas como redes. SNA proporciona tanto acceso a nuevo conocimiento como la representación de las estructuras relacionales y como éstas pueden ser consecuencia de la acción individual y colectiva. A pesar de que tanto el SNA como el Trabajo Social tienen su foco en las relaciones y el comportamiento, de

  11. An approach to take into account societal expectations for water quality monitoring: methodology and results for radionuclides

    Energy Technology Data Exchange (ETDEWEB)

    Leclerc, Elisabeth; Maitre, Melanie [Andra, French agency for radioactive waste management, 1-7 rue Jean Monnet, 92298 Chatenay-Malabry Cedex (France); Calmon, Philippe [IRSN, French Institute for Radiological Protection and Nuclear Safety, BP 3- 13115 Saint- Paul-Lez-Durance Cedex (France); Marang, Laura [EdF Electricite de France 6, Quai Wattier, 78400 Chatou (France)

    2014-07-01

    others characterized by a pluralistic approach which integrates two kinds of partners: a first group including local stakeholders concerned by the result of the exercise of prioritization and a second group including scientific and technical experts involved in sanitary or environmental risks assessments. The APPRIOS program comes in 4 different stages where experts et stakeholders are integrated: 1 - Choice of the substances to be considered (more than 400 pollutants including 17 radionuclides); 2 - Choice of 8 criteria for prioritization (solubility and water/sediment distribution coefficient, persistence, toxicity, eco-toxicity, sensitive human groups, natural or artificial sources, current local distribution, critical concentrations); 3 - Revealing of the preferences of each group: weight granted to each criteria; 4 - Multi-criteria analysis (mathematical method based on the software ELECTRE). This step is based on the allocation, for each substance, of a note for each criteria considering the available knowledge (databases, reports, calculations, expert judgment-). The list of priority substances is then revealed to the groups of experts and stakeholders as a basis for the optimization of water quality monitoring. (authors)

  12. ABOUT THE INTEGRATED FORMATIONS AND METHODOLOGICAL APPROACHES TO THE ASSESSMENT OF THE EFFICIENCY OF THEIR FUNCTIONING IN AGRO-INDUSTRIAL COMPLEX

    Directory of Open Access Journals (Sweden)

    Lalayan G. G.

    2015-06-01

    Full Text Available The main directions and tendencies of development of the Russian economy are considered in the article. The strategic role of agro-industrial complex in providing food and economic security of the country is noted. The basic provisions of Strategy of social and economic development of agro-industrial complex of the Russian Federation till 2020 are analyzed. It is established that further development of cooperation and integration belongs to number of the priority directions laid down in the Strategy. The main types of the integrated structures in agro-industrial complex are considered. The most perfect organizational forms of the integrated formations in the system of agribusiness are allocated: agroholding, agrocorporation, financial and agro-industrial group, cluster. It is noticed that in the Russian agro-industrial sector the greatest distribution was gained by the vertically integrated structures of holding type. The attention is focused on the aspects of formation and functioning of clusters as an innovative form of integration. The relevance and necessity of an assessment of efficiency of the creation and functioning of the integrated structures is emphasized. The main methodological approaches to an assessment of the efficiency of integration in agro-industrial complex are considered on the basis of the analysis of domestic and foreign references. The lack of a unified approach to the problem under consideration is revealed. It is established that method of "cost-effectiveness" is the most widespread among domestic economists. The expediency of application of synergistic approach for determination of efficiency of integration is caused. The authors emphasized the need for a comprehensive assessment of efficiency of activity of agro-industrial units on the basis of the main provisions of the existing approaches

  13. What is narrative therapy and what is it not?: the usefulness of Q methodology to explore accounts of White and Epston's (1990) approach to narrative therapy.

    Science.gov (United States)

    Wallis, Jennifer; Burns, Jan; Capdevila, Rose

    2011-01-01

    OBJECTIVE. 'What is narrative therapy and how do you do it?' is a question that is repeatedly asked of narrative therapy, with little consistent response. This study aimed to explore and distil out the 'common themes' of practitioner definitions of White and Epston's approach to narrative therapy. DESIGN. This was an Internet-based study involving current UK practitioners of this type of narrative therapy using a unique combination of a Delphi Panel and Q methodology. METHOD. A group of experienced practitioners were recruited into the Delphi Poll and were asked two questions about what narrative therapy is and is not, and what techniques are and are not employed. These data combined with other information formed the statements of a Q-sort that was then administered to a wider range of narrative practitioners. FINDINGS. The Delphi Panel agreed on a number of key points relating to the theory, politics and practice of narrative therapy. The Q-sort produced eight distinct accounts of narrative therapy and a number of dimensions along which these different positions could be distinguished. These included narrative therapy as a political stance and integration with other approaches. CONCLUSIONS. For any therapeutic model to demonstrate its efficacy and attract proponents, an accepted definition of its components and practice should preferably be established. This study has provided some data for the UK application of White and Epston's narrative therapy, which may then assist in forming a firmer base for further research and practice.

  14. Application of laser ablation ICP-MS and traditional techniques to the study of black crusts on building stones: a new methodological approach.

    Science.gov (United States)

    Barca, Donatella; Belfiore, Cristina Maria; Crisci, Gino Mirocle; La Russa, Mauro Francesco; Pezzino, Antonino; Ruffolo, Silvestro Antonio

    2010-09-01

    In this work, we propose an innovative application of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) as a methodological approach for the chemical characterisation of black crusts on stone monuments, associated with traditional micro-morphological (optical and scanning electron microscopy) and infrared spectroscopic techniques (FTIR). This new approach was tested on black crusts developing on two marble substrates, one, the columns of the San Cosimato cloister in Rome, and the other, a sculpture representing an angel, located in Pessano con Bornago, a small industrial town near Milan. The main aim of this study was to develop and test the reliability of the LA-ICP-MS analytical method on black crusts and to explore the idea that trace element concentrations in black crusts can be applied to investigate their origin and the relations between concentrations of polluting elements in black crusts and environmental conditions. The results obtained by applying traditional techniques find considerable support in the innovative method used here, which could determine the concentrations of a large number of trace elements (including heavy metals) in the black crusts examined, and thus could also be used as a reliable indicator of environmental pollution.

  15. A methodological approach to assess beach-dune system susceptibility to erosion. Cases studies from Valdelagrana spit (Spain) and Campomarino beach (Italy).

    Science.gov (United States)

    Rizzo, Angela; Aucelli, Pietro P. C.; Gracia, Javier F.; Anfuso, Giorgio; Rosskopf, Carmen M.

    2016-04-01

    Dunes provide many important services to coastal areas, such as coastal erosion mitigation, coastal flooding protection and biological diversity. Their dynamic equilibrium and geomorphological evolution are the result of the interaction between marine and aeolian processes. Moreover, coastal dunes are characterized by a high ecological value, being a narrow strip between marine and terrestrial ecosystems and are habitats considered of community interest by the Habitats Directive 92/43/EEC. In the meantime, the significant increase of human pressure on coastal environments during the last decades has caused a strong alteration and an increase of the fragility and fragmentation of these habitats. This paper presents a methodological approach for the assessment of the beach-dune system susceptibility to erosion. The aim is to identify, at the local scale, the degree of susceptibility of coastal stretches in order to evaluate the degree of exposure of human settlements and natural environments located behind the dune system and to support actuations to appropriately improve dune management and conservation. A coastal susceptibility matrix and a corresponding Coastal Susceptibility Index (CSI) are proposed. Following the assumption that a good index should be based on a minimum amount of essential information (Cooper and McLaughlin, 1998), possibly already available or easy to be obtained (Villa and McLeod, 2002), the proposed index consisted into eight variables concerning existing beach and dune conditions, covering geomorphological, physical and anthropogenic aspects. Each variable was inserted into a GIS system and overlapped with the others through a logical overlay operation. The resulting layer was reclassified according to the formula proposed by Rangel and Anfuso (2015) allowing to calculate the CSI, which ranged from 1 (null/very low susceptibility) to 5 (very high susceptibility). In a further step, the predominant processes occurred in the last decades were

  16. Design Methodology - Design Synthesis

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup

    2003-01-01

    ABSTRACT Design Methodology shall be seen as our understanding of how to design; it is an early (emerging late 60ies) and original articulation of teachable and learnable methodics. The insight is based upon two sources: the nature of the designed artefacts and the nature of human designing. Today...... Design Methodology is part of our practice and our knowledge about designing, and it has been strongly supported by the establishing and work of a design research community. The aim of this article is to broaden the reader¿s view of designing and Design Methodology. This is done by sketching...... the development of Design Methodology through time and sketching some important approaches and methods. The development is mainly forced by changing industrial condition, by the growth of IT support for designing, but also by the growth of insight into designing created by design researchers....

  17. On methodology

    DEFF Research Database (Denmark)

    Cheesman, Robin; Faraone, Roque

    2002-01-01

    This is an English version of the methodology chapter in the authors' book "El caso Berríos: Estudio sobre información errónea, desinformación y manipulación de la opinión pública".......This is an English version of the methodology chapter in the authors' book "El caso Berríos: Estudio sobre información errónea, desinformación y manipulación de la opinión pública"....

  18. Research Methodology: A Practitioner Approach

    Science.gov (United States)

    Singh, Sukhpal; Chana, Inderveer; Singh, Maninder

    2015-01-01

    The ultimate goal of scientific research is publication so as to showcase the research outcomes. Scientists, starting as graduate students, are measured primarily not by their dexterity in laboratory manipulations, not by their innate knowledge of either broad or narrow scientific subjects, and certainly not by their wit or charm; they are…

  19. Reflexões metodológicas para o estudo das práticas alimentares Methodological approaches on the studies of food practices

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Poulain

    2003-12-01

    Full Text Available A alimentação humana, envolvendo aspectos psicológicos, fisiológicos e socioculturais, é um fenômeno de grande complexidade e, em assim sendo, o estudo das práticas alimentares tem suscitado o desenvolvimento de instrumentos e métodos no interior de várias disciplinas. Neste artigo, que apresenta a alimentação humana sob abordagem da Sociologia e da Antropologia, definem-se as diferentes dimensões do espaço social alimentar, desde o registro do consumo alimentar até os processos de diferenciação social envolvendo as formas de cozinhar, as formas de consumir e a temporalidade. Analisam-se os diferentes tipos de dados que podem ser utilizados, tomando-se o cuidado de distinguir os dados comportamentais (que podem ser obtidos tanto pela observação quanto pela declaração dos dados de representação. Apresentam-se, em seguida, os diferentes instrumentos de coleta e as vias de entrada no fenômeno alimentar. Esses instrumentos metodológicos, construídos no interior de um quadro teórico-sociológico, são propostos aos pesquisadores da área, objetivando a construção de uma possível visão comum, que proporcione uma abordagem pluridisciplinar do fato alimentar.Human nutrition is a very complex phenomenon as it invites at the same time the physiology, the psychology and the socio-cultural. That's also why food practice measures have caused the development of tools and methodologies within several disciplines. This article presents the approach of sociology and anthropology. It defines first of all the different dimensions of the social food space; from the eatable order to the process of social differentiation via the culinary, the consumption forms and the temporality. It analyses in detail the data types which can be used taking care in distinguishing the behavioural data that can be obtained either by observation or by declaration from the representation data. It presents the different collect tools and the ways of entry in

  20. Methodological aspects of a pattern-scaling approach to produce global fields of monthly means of daily maximum and minimum temperature

    Science.gov (United States)

    Kremser, S.; Bodeker, G. E.; Lewis, J.

    2014-01-01

    A Climate Pattern-Scaling Model (CPSM) that simulates global patterns of climate change, for a prescribed emissions scenario, is described. A CPSM works by quantitatively establishing the statistical relationship between a climate variable at a specific location (e.g. daily maximum surface temperature, Tmax) and one or more predictor time series (e.g. global mean surface temperature, Tglobal) - referred to as the "training" of the CPSM. This training uses a regression model to derive fit coefficients that describe the statistical relationship between the predictor time series and the target climate variable time series. Once that relationship has been determined, and given the predictor time series for any greenhouse gas (GHG) emissions scenario, the change in the climate variable of interest can be reconstructed - referred to as the "application" of the CPSM. The advantage of using a CPSM rather than a typical atmosphere-ocean global climate model (AOGCM) is that the predictor time series required by the CPSM can usually be generated quickly using a simple climate model (SCM) for any prescribed GHG emissions scenario and then applied to generate global fields of the climate variable of interest. The training can be performed either on historical measurements or on output from an AOGCM. Using model output from 21st century simulations has the advantage that the climate change signal is more pronounced than in historical data and therefore a more robust statistical relationship is obtained. The disadvantage of using AOGCM output is that the CPSM training might be compromised by any AOGCM inadequacies. For the purposes of exploring the various methodological aspects of the CPSM approach, AOGCM output was used in this study to train the CPSM. These investigations of the CPSM methodology focus on monthly mean fields of daily temperature extremes (Tmax and Tmin). The methodological aspects of the CPSM explored in this study include (1) investigation of the advantage

  1. Land evaluation methodology

    OpenAIRE

    Lustig, Thomas

    1998-01-01

    This paper reviews non-computerised and computerised land evaluation methods or methodologies, and realises the difficulties to incorporate biophysical and socioeconomic factors from different levels. Therefore, this paper theorises an alternative land evaluation approach, which is tested and elaborated in an agricultural community in the North of Chile. The basis of the approach relies on holistic thinking and attempts to evaluate the potential for improving assumed unsustainable goat manage...

  2. Study of levan productivity from Bacillus subtilis Natto by surface response methodology and its antitumor activity against HepG2 cells using metabolomic approach.

    Science.gov (United States)

    Cabral de Melo, Fernando Cesar Bazani; Borsato, Dionísio; de Macedo Júnior, Fernando César; Mantovani, Mario Sérgio; Luiz, Rodrigo Cabral; Colabone-Celligoi, Maria Antonia-Pedrine

    2015-11-01

    Levan productivity of Bacillus subtilis Natto was evaluated in submerged culture varying the pH, temperature and culture time, using factorial design and response surface methodology. The characterization of levan molecular weight was performed by HPSEC and its antitumor activity against HepG2 cells using metabolomic approach was also evaluated. At first, the variables investigated, as well as their interactions, demonstrated significant effect. Further, a second design using the same variables at different levels was developed. Thus, according to the model, an optimized value corresponding to 5.82 g.L⁻¹.h⁻¹ was achieved at pH 8, 39.5°C in 21 hours, the highest value reported so far. After analysis by HPSEC, two molecular weights were obtained corresponding to 72.37 and 4146 kDa. The levan promoted an increase of acetate, alanine, lactate and phosphocreatine in HepG2 cells suggesting an alteration in the bioenergetics pathways and cellular homeostasis by intracellular accumulation of lactate, justifying its antitumor activity.

  3. Conserved charged amino acids are key determinants for fatty acid binding proteins (FABPs)-membrane interactions. A multi-methodological computational approach.

    Science.gov (United States)

    Zamarreño, Fernando; Giorgetti, Alejandro; Amundarain, María Julia; Viso, Juan Francisco; Córsico, Betina; Costabel, Marcelo D

    2017-03-16

    Based on the analysis of the mechanism of ligand transfer to membranes employing in vitro methods, Fatty Acid Binding Protein (FABP) family has been divided in two subgroups: collisional and diffusional FABPs. Although the collisional mechanism has been well characterized employing in vitro methods, the structural features responsible for the difference between collisional and diffusional mechanisms remain uncertain. In this work, we have identified the amino acids putatively responsible for the interaction with membranes of both, collisional and diffusional, subgroups of FABPs. Moreover, we show how specific changes in FABPs' structure could change the mechanism of interaction with membranes. We have computed protein-membrane interaction energies for members of each subgroup of the family, and performed Molecular Dynamics simulations that have shown different configurations for the initial interaction between FABPs and membranes. In order to generalize our hypothesis, we extended the electrostatic and bioinformatics analysis over FABPs of different mammalian genus. Also, our methodological approach could be used for other systems involving protein-membrane interactions.

  4. A Decision Support System (GesCoN for managing fertigation in open field vegetable crops. Part I - Methodological approach and description of the software

    Directory of Open Access Journals (Sweden)

    Antonio eElia

    2015-05-01

    Full Text Available Reduced water availability and environmental pollution caused by nitrogen (N losses have increased the need for rational management of irrigation and N fertilization in horticultural systems. Decision support systems (DSS could be powerful tools to assist farmers to improve irrigation and N fertilization efficiency. Currently, fertilization by drip irrigation system (fertigation is used for many vegetable crops around the world. The paper illustrates the theoretical basis, the methodological approach and the structure of a DSS called GesCoN for fertigation management in open field vegetable crops. The DSS is based on daily water and N balance, considering the water lost by evapotranspiration (ET and the N content in the aerial part of the crop (N uptake as subtraction and the availability of water and N in the wet soil volume most effected by roots as the positive part. For the water balance, reference ET can be estimated using the Penman-Monteith (PM or the Priestley-Taylor and Hargreaves models, specifically calibrated under local conditions. Both single or dual Kc approach can be used to calculate crop ET. Rain runoff and deep percolation are considered to calculate the effective rainfall. The soil volume most effected by the roots, the wet soil under emitters and their interactions are modelled. Crop growth is modelled by a non-linear logistic function on the basis of thermal time, but the model takes into account thermal and water stresses and allows an in-season calibration through a dynamic adaptation of the growth rate to the specific genetic and environmental conditions. N crop demand is related to DM accumulation by the N critical curve. N mineralization from soil organic matter is daily estimated. The DSS helps users to evaluate the daily amount of water and N fertilizer that has to be applied in order to fulfil the water and N-crop requirements to achieve the maximum potential yield, while reducing the risk of nitrate outflows.

  5. A decision support system (GesCoN) for managing fertigation in open field vegetable crops. Part I-methodological approach and description of the software.

    Science.gov (United States)

    Elia, Antonio; Conversa, Giulia

    2015-01-01

    Reduced water availability and environmental pollution caused by nitrogen (N) losses have increased the need for rational management of irrigation and N fertilization in horticultural systems. Decision support systems (DSS) could be powerful tools to assist farmers to improve irrigation and N fertilization efficiency. Currently, fertilization by drip irrigation system (fertigation) is used for many vegetable crops around the world. The paper illustrates the theoretical basis, the methodological approach and the structure of a DSS called GesCoN for fertigation management in open field vegetable crops. The DSS is based on daily water and N balance, considering the water lost by evapotranspiration (ET) and the N content in the aerial part of the crop (N uptake) as subtraction and the availability of water and N in the wet soil volume most effected by roots as the positive part. For the water balance, reference ET can be estimated using the Penman-Monteith (PM) or the Priestley-Taylor and Hargreaves models, specifically calibrated under local conditions. Both single or dual Kc approach can be used to calculate crop ET. Rain runoff and deep percolation are considered to calculate the effective rainfall. The soil volume most affected by the roots, the wet soil under emitters and their interactions are modeled. Crop growth is modeled by a non-linear logistic function on the basis of thermal time, but the model takes into account thermal and water stresses and allows an in-season calibration through a dynamic adaptation of the growth rate to the specific genetic and environmental conditions. N crop demand is related to DM accumulation by the N critical curve. N mineralization from soil organic matter is daily estimated. The DSS helps users to evaluate the daily amount of water and N fertilizer that has to be applied in order to fulfill the water and N-crop requirements to achieve the maximum potential yield, while reducing the risk of nitrate outflows.

  6. A decision support system (GesCoN) for managing fertigation in open field vegetable crops. Part I—methodological approach and description of the software

    Science.gov (United States)

    Elia, Antonio; Conversa, Giulia

    2015-01-01

    Reduced water availability and environmental pollution caused by nitrogen (N) losses have increased the need for rational management of irrigation and N fertilization in horticultural systems. Decision support systems (DSS) could be powerful tools to assist farmers to improve irrigation and N fertilization efficiency. Currently, fertilization by drip irrigation system (fertigation) is used for many vegetable crops around the world. The paper illustrates the theoretical basis, the methodological approach and the structure of a DSS called GesCoN for fertigation management in open field vegetable crops. The DSS is based on daily water and N balance, considering the water lost by evapotranspiration (ET) and the N content in the aerial part of the crop (N uptake) as subtraction and the availability of water and N in the wet soil volume most effected by roots as the positive part. For the water balance, reference ET can be estimated using the Penman–Monteith (PM) or the Priestley–Taylor and Hargreaves models, specifically calibrated under local conditions. Both single or dual Kc approach can be used to calculate crop ET. Rain runoff and deep percolation are considered to calculate the effective rainfall. The soil volume most affected by the roots, the wet soil under emitters and their interactions are modeled. Crop growth is modeled by a non-linear logistic function on the basis of thermal time, but the model takes into account thermal and water stresses and allows an in-season calibration through a dynamic adaptation of the growth rate to the specific genetic and environmental conditions. N crop demand is related to DM accumulation by the N critical curve. N mineralization from soil organic matter is daily estimated. The DSS helps users to evaluate the daily amount of water and N fertilizer that has to be applied in order to fulfill the water and N-crop requirements to achieve the maximum potential yield, while reducing the risk of nitrate outflows. PMID:26042128

  7. Methodological guidelines

    Energy Technology Data Exchange (ETDEWEB)

    Halsnaes, K.; Callaway, J.M.; Meyer, H.J.

    1999-04-01

    The guideline document establishes a general overview of the main components of climate change mitigation assessment. This includes an outline of key economic concepts, scenario structure, common assumptions, modelling tools and country study assumptions. The guidelines are supported by Handbook Reports that contain more detailed specifications of calculation standards, input assumptions and available tools. The major objectives of the project have been provided a methodology, an implementing framework and a reporting system which countries can follow in meeting their future reporting obligations under the FCCC and for GEF enabling activities. The project builds upon the methodology development and application in the UNEP National Abatement Coasting Studies (UNEP, 1994a). The various elements provide countries with a road map for conducting climate change mitigation studies and submitting national reports as required by the FCCC. (au) 121 refs.

  8. Situating methodology within qualitative research.

    Science.gov (United States)

    Kramer-Kile, Marnie L

    2012-01-01

    Qualitative nurse researchers are required to make deliberate and sometimes complex methodological decisions about their work. Methodology in qualitative research is a comprehensive approach in which theory (ideas) and method (doing) are brought into close alignment. It can be difficult, at times, to understand the concept of methodology. The purpose of this research column is to: (1) define qualitative methodology; (2) illuminate the relationship between epistemology, ontology and methodology; (3) explicate the connection between theory and method in qualitative research design; and 4) highlight relevant examples of methodological decisions made within cardiovascular nursing research. Although there is no "one set way" to do qualitative research, all qualitative researchers should account for the choices they make throughout the research process and articulate their methodological decision-making along the way.

  9. Changing methodologies in TESOL

    CERN Document Server

    Spiro, Jane

    2013-01-01

    Covering core topics from vocabulary and grammar to teaching, writing speaking and listening, this textbook shows you how to link research to practice in TESOL methodology. It emphasises how current understandings have impacted on the language classroom worldwide and investigates the meaning of 'methods' and 'methodology' and the importance of these for the teacher: as well as the underlying assumptions and beliefs teachers bring to bear in their practice. By introducing you to language teaching approaches, you will explore the way these are influenced by developments in our understanding of l

  10. Methodology for research I.

    Science.gov (United States)

    Garg, Rakesh

    2016-09-01

    The conduct of research requires a systematic approach involving diligent planning and its execution as planned. It comprises various essential predefined components such as aims, population, conduct/technique, outcome and statistical considerations. These need to be objective, reliable and in a repeatable format. Hence, the understanding of the basic aspects of methodology is essential for any researcher. This is a narrative review and focuses on various aspects of the methodology for conduct of a clinical research. The relevant keywords were used for literature search from various databases and from bibliographies of the articles.

  11. Analysis of market competitive structure: The new methodological approach based in the using; El analisis de la estructura competitiva del mercado: Un nuevo enfoque metodologico basado en la situacion de uso

    Energy Technology Data Exchange (ETDEWEB)

    Romero de la Fuente, J.; Yague Guillen, M. J.

    2007-07-01

    This paper proposes a new methodological approach to identify market competitive structure, applying usage situation concept in positioning analysis. Dimensions used by consumer to classify products are identified using Correspondence Analysis and competitive groups are formed. Results are validated with Discriminant Analysis. (Author) 23 refs.

  12. Internalism as Methodology

    Directory of Open Access Journals (Sweden)

    Terje Lohndal

    2009-10-01

    Full Text Available This paper scrutinizes the recent proposal made by Lassiter (2008 that the dichotomy between Chomskyan internalism and Dummett-type externalism is misguided and should be overcome by an approach that incorporates sociolinguistic concepts such as speakers’ dispositions to defer. We argue that Lassiter’s arguments are flawed and based on a serious misunder-standing of the internalist approach to the study of natural language, failing to appreciate its methodological nature and conclude that Lassiter’s socio-linguistic approach is just another instance of externalist attempts with little hope of scientific achievement.

  13. Meta-análise em pesquisas científicas: enfoque em metodologias Meta analysis in scientific research: a methodological approach

    Directory of Open Access Journals (Sweden)

    P.A. Lovatto

    2007-07-01

    Full Text Available Este texto descreve os princípios básicos de sistematização com enfoque em meta-análise. É apresentado o estado da arte da meta-análise, recuperando informações de sua evolução e metodologias básicas para sua realização. São descritos seus antecedentes históricos, os limites das abordagens clássicas de revisão de literatura, as bases conceituais, os objetivos e justificativas. É indicada uma metodologia geral para realização da meta-análise. São apresentados os critérios para a definição dos objetivos. São descritos os procedimentos de sistematização das informações e gestão de base bibliográfica de dados destinada aos estudos meta-analíticos (seleção, codificação, filtragem de dados. São apresentadas as análises mais comuns (gráfica, ponderações, a escolha do modelo estatístico (um fator explicativo qualitativo, um efeito qualitativo ou quantitativo, os fatores de interferência, os procedimentos pós-analíticos (variações residuais, heterogeneidade entre resultados. Em síntese, este texto mostra que a meta-análise é superior às formas tradicionais de revisão de literatura por estimar com maior precisão os efeitos dos tratamentos, ajustando-os para a heterogeneidade experimental. No entanto, a meta-análise exige os efeitos na sistematização e análise dos resultados da pesquisa.This text describes a basic approach of systematization with focus on meta-analysis. It is presented the art state of the meta-analysis, recovering information of its evolution and basic methodologies for its accomplishment. In this text are described the historical antecedents of meta-analysis, the limits of the classic approaches of literature review, the conceptual bases and the objectives. It is indicated a general methodology for meta-analysis procedures. The criteria for the definition of the objectives are presented. The procedures of the systematization and management of bibliographical data base selected to

  14. Multifractal methodology

    CERN Document Server

    Salat, Hadrien; Arcaute, Elsa

    2016-01-01

    Various methods have been developed independently to study the multifractality of measures in many different contexts. Although they all convey the same intuitive idea of giving a "dimension" to sets where a quantity scales similarly within a space, they are not necessarily equivalent on a more rigorous level. This review article aims at unifying the multifractal methodology by presenting the multifractal theoretical framework and principal practical methods, namely the moment method, the histogram method, multifractal detrended fluctuation analysis (MDFA) and modulus maxima wavelet transform (MMWT), with a comparative and interpretative eye.

  15. A Functional HAZOP Methodology

    DEFF Research Database (Denmark)

    Liin, Netta; Lind, Morten; Jensen, Niels

    2010-01-01

    A HAZOP methodology is presented where a functional plant model assists in a goal oriented decomposition of the plant purpose into the means of achieving the purpose. This approach leads to nodes with simple functions from which the selection of process and deviation variables follow directly....... The functional HAZOP methodology lends itself directly for implementation into a computer aided reasoning tool to perform root cause and consequence analysis. Such a tool can facilitate finding causes and/or consequences far away from the site of the deviation. A functional HAZOP assistant is proposed...... and investigated in a HAZOP study of an industrial scale Indirect Vapor Recompression Distillation pilot Plant (IVaRDiP) at DTU-Chemical and Biochemical Engineering. The study shows that the functional HAZOP methodology provides a very efficient paradigm for facilitating HAZOP studies and for enabling reasoning...

  16. Detection, characterization and quantification of inorganic engineered nanomaterials: A review of techniques and methodological approaches for the analysis of complex samples

    Energy Technology Data Exchange (ETDEWEB)

    Laborda, Francisco, E-mail: flaborda@unizar.es; Bolea, Eduardo; Cepriá, Gemma; Gómez, María T.; Jiménez, María S.; Pérez-Arantegui, Josefina; Castillo, Juan R.

    2016-01-21

    dealing with complex samples. Single- and multi-method approaches applied to solve the nanometrological challenges posed by a variety of stakeholders are also presented. - Highlights: • The challenge to analyze inorganic nanomaterials is described. • Techniques for detection, characterization and quantification of inorganic nanomaterials are presented. • Sample preparation methods for the analysis of nanomaterials in complex samples are presented. • Methodological approaches posed by stakeholders for solving nanometrological problems are discussed.

  17. Practical implications of rapid development methodologies

    CSIR Research Space (South Africa)

    Gerber, A

    2007-11-01

    Full Text Available Rapid development methodologies are popular approaches for the development of modern software systems. The goals of these methodologies are the inclusion of the client into the analysis, design and implementation activities, as well...

  18. MOTOR VEHICLE SAFETY RESEARCH METHODOLOGY

    Directory of Open Access Journals (Sweden)

    A. Stepanov

    2015-07-01

    Full Text Available The issues of vehicle safety are considered. The methodology of approach to analyzing and solving the problem of safety management of vehicles and overall traffic is offered. The distinctive features of organization and management of vehicle safety are shown. There has been drawn a conclusion that the methodological approach to solving traffic safety problems is reduced to selection and classification of safety needs.

  19. Research Methodology

    CERN Document Server

    Rajasekar, S; Philomination, P

    2006-01-01

    In this manuscript various components of research are listed and briefly discussed. The topics considered in this write-up cover a part of the research methodology paper of Master of Philosophy (M.Phil.) course and Doctor of Philosophy (Ph.D.) course. The manuscript is intended for students and research scholars of science subjects such as mathematics, physics, chemistry, statistics, biology and computer science. Various stages of research are discussed in detail. Special care has been taken to motivate the young researchers to take up challenging problems. Ten assignment works are given. For the benefit of young researchers a short interview with three eminent scientists is included at the end of the manuscript.

  20. Soft Systems Methodology

    Science.gov (United States)

    Checkland, Peter; Poulter, John

    Soft systems methodology (SSM) is an approach for tackling problematical, messy situations of all kinds. It is an action-oriented process of inquiry into problematic situations in which users learn their way from finding out about the situation, to taking action to improve it. The learning emerges via an organised process in which the situation is explored using a set of models of purposeful action (each built to encapsulate a single worldview) as intellectual devices, or tools, to inform and structure discussion about a situation and how it might be improved. This paper, written by the original developer Peter Checkland and practitioner John Poulter, gives a clear and concise account of the approach that covers SSM's specific techniques, the learning cycle process of the methodology and the craft skills which practitioners develop. This concise but theoretically robust account nevertheless includes the fundamental concepts, techniques, core tenets described through a wide range of settings.

  1. Scientific-methodological approaches to designing risk-oriented model of control and surveillance activities in the sphere of consumer rights protection

    Directory of Open Access Journals (Sweden)

    N.V. Zaitseva

    2017-06-01

    Full Text Available We present scientific-methodological approaches to defining risk categories of economic entities which are subject to surveillance in the sphere of consumer rights protection. Risk is suggested to be assessed as a product of violations frequency comprising violations of separate provisions of the law on consumer rights protection detected in the course of scheduled and unscheduled inspections; a number of claims per one detected violation which were satisfied by courts in favor of consumers; each separate case of harm accepted by court in money terms (as a sum of physical and moral damage to health and damage to property; and coefficient of a potential impact scope which differentiates risks for economic entities belonging to micro-, small, medium-sized and large business. Our information sources are official statistic data obtained due to realization of state control in the sphere of consumer rights protection and court practice collected in all the RF regions over 2012–2016. It is shown that a share of economic entities with extremely high risk potential which can cause total material damage to consumers in sums greater than 10 million rubles per year amounts to about 0.15 % of the total number of economic entities (both juridical persons and private entrepreneurs; economic entities with high risk potential account for about 2 %. Such groups are made of companies involved in financial markets, share construction services, insurance and tourism. About 23 % of juridical persons and private entrepreneurs can be classified as having low risk potential and they can be excluded from scheduled inspections. Economic entities structure in general corresponds to world practices. It is shown that risk-oriented surveillance model development requires improvements in keeping registers of juridical persons and private entrepreneurs as such registers should contain comprehensive information; it is necessary for correct risk category (or hazard category

  2. Methodological approach to the optimization of management system selection in the sphere of industrial enterprises` corporate culture from position of its effectiveness

    Directory of Open Access Journals (Sweden)

    M.I. Ovcharenko

    2013-09-01

    Full Text Available The aim of the article. The article presents the methodological approach to optimization of the choice of management actions in the sphere of corporate culture development from position of its economic efficiency. The author suggests four levels of corporate culture high, heightened, medium and low in accordance with two management instruments of evolutionary and revolutionary character.The results of the analysis. The author found that the cost of managing the development of corporate culture are derived from differentiation and development of personnel incentives. The amount and structure of the cost of management measure implementation depends on selected instrument of corporate culture.Finding of optimal value in terms of tangible and intangible incentives that provides a balance of economic interests of employees and managers is very important in this case.To assess the economic efficiency of corporate culture we offer an original model that consists of the following phases:assessment and determination of the current state of corporate culture at the enterprise;identifying of key directions of corporate culture development;planning of actual management costs dynamics;formation of mechanism of economic benefits calculating;the implementation of expert evaluating the impact of interventions using selected indicators;final calculation of economic efficiency of corporate culture improvement using two methods the diagnostic and control and diagnostic search.The author indicated that at the present stage of domestic industries` development it is important to use diagnostic search in efficiency of corporate culture assessing.We believe that for the purpose of evaluating the effectiveness , it is appropriate to limit the application of methods aimed at determining the degree of deviation of actual results from potentially possible in the market, with appropriate adaptation to the specific conditions of carrying out in domestic industry

  3. A goal programming approach for a joint design of macroeconomic and environmental policies: a methodological proposal and an application to the Spanish economy.

    Science.gov (United States)

    André, Francisco J; Cardenete, M Alejandro; Romero, Carlos

    2009-05-01

    The economic policy needs to pay increasingly more attention to the environmental issues, which requires the development of methodologies able to incorporate environmental, as well as macroeconomic, goals in the design of public policies. Starting from this observation, this article proposes a methodology based upon a Simonian satisficing logic made operational with the help of goal programming (GP) models, to address the joint design of macroeconomic and environmental policies. The methodology is applied to the Spanish economy, where a joint policy is elicited, taking into consideration macroeconomic goals (economic growth, inflation, unemployment, public deficit) and environmental goals (CO(2), NO( x ) and SO( x ) emissions) within the context of a computable general equilibrium model. The results show how the government can "fine-tune" its policy according to different criteria using GP models. The resulting policies aggregate the environmental and the economic goals in different ways: maximum aggregate performance, maximum balance and a lexicographic hierarchy of the goals.

  4. A Goal Programming Approach for a Joint Design of Macroeconomic and Environmental Policies: A Methodological Proposal and an Application to the Spanish Economy

    Science.gov (United States)

    André, Francisco J.; Cardenete, M. Alejandro; Romero, Carlos

    2009-05-01

    The economic policy needs to pay increasingly more attention to the environmental issues, which requires the development of methodologies able to incorporate environmental, as well as macroeconomic, goals in the design of public policies. Starting from this observation, this article proposes a methodology based upon a Simonian satisficing logic made operational with the help of goal programming (GP) models, to address the joint design of macroeconomic and environmental policies. The methodology is applied to the Spanish economy, where a joint policy is elicited, taking into consideration macroeconomic goals (economic growth, inflation, unemployment, public deficit) and environmental goals (CO2, NO x and SO x emissions) within the context of a computable general equilibrium model. The results show how the government can “fine-tune” its policy according to different criteria using GP models. The resulting policies aggregate the environmental and the economic goals in different ways: maximum aggregate performance, maximum balance and a lexicographic hierarchy of the goals.

  5. Performance and Perception in the Flipped Learning Model: An Initial Approach to Evaluate the Effectiveness of a New Teaching Methodology in a General Science Classroom

    Science.gov (United States)

    González-Gómez, David; Jeong, Jin Su; Airado Rodríguez, Diego; Cañada-Cañada, Florentina

    2016-06-01

    "Flipped classroom" teaching methodology is a type of blended learning in which the traditional class setting is inverted. Lecture is shifted outside of class, while the classroom time is employed to solve problems or doing practical works through the discussion/peer collaboration of students and instructors. This relatively new instructional methodology claims that flipping your classroom engages more effectively students with the learning process, achieving better teaching results. Thus, this research aimed to evaluate the effects of the flipped classroom on the students' performance and perception of this new methodology. This study was conducted in a general science course, sophomore of the Primary Education bachelor degree in the Training Teaching School of the University of Extremadura (Spain) during the course 2014/2015. In order to assess the suitability of the proposed methodology, the class was divided in two groups. For the first group, a traditional methodology was followed, and it was used as control. On the other hand, the "flipped classroom" methodology was used in the second group, where the students were given diverse materials, such as video lessons and reading materials, before the class to be revised at home by them. Online questionnaires were as well provided to assess the progress of the students before the class. Finally, the results were compared in terms of students' achievements and a post-task survey was also conducted to know the students' perceptions. A statistically significant difference was found on all assessments with the flipped class students performing higher on average. In addition, most students had a favorable perception about the flipped classroom noting the ability to pause, rewind and review lectures, as well as increased individualized learning and increased teacher availability.

  6. Performance and Perception in the Flipped Learning Model: An Initial Approach to Evaluate the Effectiveness of a New Teaching Methodology in a General Science Classroom

    Science.gov (United States)

    González-Gómez, David; Jeong, Jin Su; Airado Rodríguez, Diego; Cañada-Cañada, Florentina

    2016-01-01

    "Flipped classroom" teaching methodology is a type of blended learning in which the traditional class setting is inverted. Lecture is shifted outside of class, while the classroom time is employed to solve problems or doing practical works through the discussion/peer collaboration of students and instructors. This relatively new…

  7. Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents : a systematic review and evaluation of methodological approaches

    NARCIS (Netherlands)

    Fazeli Farsani, S; van der Aa, M P; van der Vorst, M M J; Knibbe, C A J; de Boer, A

    2013-01-01

    AIMS/HYPOTHESIS: This study aimed to systematically review what has been reported on the incidence and prevalence of type 2 diabetes in children and adolescents, to scrutinise the methodological issues observed in the included studies and to prepare recommendations for future research and surveillan

  8. Confidence/Confidentiality: A Comparison of Methodological Approaches Used in a Field Study of Children's Political Attitudes in Bogota, Colombia, and Educational Evaluation.

    Science.gov (United States)

    Bailey, Susan McGee; Hunter, William J.

    This paper examines how potential conflicts produced by ethical issues such as confidence and confidentiality can affect the research methodology of educational research and evaluation projects. Despite the differences in site selection, clientele, and relationship to treatment, both evaluators and researchers must make adjustments in method to…

  9. Policy Implications for Continuous Employment Decisions of High School Principals: An Alternative Methodological Approach for Using High-Stakes Testing Outcomes

    Science.gov (United States)

    Young, I. Phillip; Fawcett, Paul

    2013-01-01

    Several teacher models exist for using high-stakes testing outcomes to make continuous employment decisions for principals. These models are reviewed, and specific flaws are noted if these models are retrofitted for principals. To address these flaws, a different methodology is proposed on the basis of actual field data. Specially addressed are…

  10. A multi-methodological approach to study the temporal and spatial distribution of air quality related to road transport emissions in Madrid, Spain

    Science.gov (United States)

    Perez, Pedro; Miranda, Regina

    2013-04-01

    emission inventory, together with the mobile source's parameters and the disaggregated transport activity data. The paper will also identify emission and concentration differences and gradients of certain magnitude/factor (e.g. comparison between estimated ATPs hourly concentrations in Madrid City Center and in the peripheries). Furthermore, because of the higher contribution of road mobile sources to GHGs and ATPs emissions in Madrid, small gradients between urban highways and residential areas will be expected. Second, the paper objectives are to develop valid methods and approaches to measure air quality and to develop valid road transport emission inventories to assess correlations between external costs, epidemiology and emissions in order to reveal how traffic pollution affects people exposure to key contaminants and disease development, and identify susceptible emission scenarios and health impacts. We have conducted general emission inventory studies providing preliminary evidence of regional road transport air pollution impacts on external cost growth and disease development. Third, we also aim to demonstrate short and long-term impacts of road transport emissions on external costs development using innovative multi-methodological methods interfaced with environmental chemistry and meteorology following meteorological and chemical fields with contrasting high/low traffic emissions in several linked components involving: air pollutant assessment using local measurements, height of the boundary layer, meteorological environment interactions on external costs and epidemiology, mapping of Madrid (identifying gradients of emissions), integrative causal modeling using statistical models, and trend and scenario analyses on external costs and impacts on human health. Meteorological and chemical fields will be obtained from local records collected by surface meteorological and air quality stations. These two sets of fields define the horizontal and vertical profiles of

  11. Methodology, Meditation, and Mindfulness

    Directory of Open Access Journals (Sweden)

    Balveer Singh Sikh

    2016-04-01

    Full Text Available Understanding the nondualistic nature of mindfulness is a complex and challenging task particularly when most clinical psychology draws from Western methodologies and methods. In this article, we argue that the integration of philosophical hermeneutics with Eastern philosophy and practices may provide a methodology and methods to research mindfulness practice. Mindfulness hermeneutics brings together the nondualistically aligned Western philosophies of Heidegger and Gadamer and selected Eastern philosophies and practices in an effort to bridge the gap between these differing worldviews. Based on the following: (1 fusion of horizons, (2 being in a hermeneutic circle, (3 understanding as intrinsic to awareness, and (4 the ongoing practice of meditation, a mindfulness hermeneutic approach was used to illuminate deeper understandings of mindfulness practice in ways that are congruent with its underpinning philosophies.

  12. METHODOLOGICAL BASES OF OUTSOURCING

    Directory of Open Access Journals (Sweden)

    Lanskaya D. V.

    2014-09-01

    Full Text Available Outsourcing is investigated from a position of finding steady and unique competitive advantages of a public corporation due to attraction of carriers of unique intellectual and uses social capitals of the specialized companies within the institutional theory. Key researchers and events in the history of outsourcing are marked out, the existing approaches to definition of the concept of outsourcing, advantage and risks from application of technology of outsourcing are considered. It is established that differences of outsourcing, sub-contraction and cooperation are not in the nature of the functional relations, and in the depth of considered economic terms and phenomena. The methodology of outsourcing is considered as a part of methodology of cooperation of enterprise innovative structures of being formed sector of knowledge economy

  13. Comparing a soft and a hard multi-methodology approach: Location of an IT company in the Øresund Region

    DEFF Research Database (Denmark)

    Jeppesen, Sara Lise; Barfod, Michael Bruhn; Leleur, Steen

    2007-01-01

    system applied in the STMØ project (2005-2007). The soft approach explores litmus test, CSH, SSM and SWOT analysis, while the hard method approach combines preference analysis, CBA, AHP, SMARTER, MCA and COSIMA. Both approaches are supported by simple soft methods as stakeholder analysis...

  14. Comparative studies in education: new theoretical and methodological approaches - doi: 10.4025/actascieduc.v36i1.19012

    Directory of Open Access Journals (Sweden)

    Elma Júlia Gonçalves de Carvalho

    2014-02-01

    Full Text Available Comparative methodology is an extremely rich analytic tool in educational systems. Since it identifies similar and different issues, it broadens the field of analysis and understanding on the national reality when contrasted to that of other countries, especially with their public policies and their administration of education. Several theoretical and methodological issues on comparative studies are historically investigated and the new perspectives on current comparative education are indicated. Current research demonstrates that the production of a new paradigmatic perspective, highlighting the rejection of traditional national frontiers as the only or the main categories of analysis, is on the increase. On the one hand, the above-mentioned perspective invites experts to adopt international references in the analysis of educational systems and policies and, on the other hand, makes them aware of regional differences and provides them with new horizons for their investigation.

  15. The effects of sous-vide cooking parameters on texture and cell wall modifications in two apple cultivars: A response surface methodology approach.

    Science.gov (United States)

    Ortiz, Abel; Le Meurlay, Dominique; Lara, Isabel; Symoneaux, Ronan; Madieta, Emmanuel; Mehinagic, Emira

    2017-03-01

    This work aimed at evaluating the effects of sous-vide cooking parameters, such as time and temperature and their interactions, on textural attributes of 'Mondial Gala' and 'Granny Smith' apple cultivars. For this, different response surface methodology-based models were developed. This methodology proved a suitable means for the assessment of changes in textural parameters and cell wall modifications during the processing of apples. 'Mondial Gala' fruit displayed better aptitude for the preservation of textural properties after high-temperature processing conditions and were therefore apparently more suited to sous-vide cooking than 'Granny Smith' apples. Pectin methylesterase activity levels in 'Mondial Gala' apples were enhanced at mild temperatures and pectins in this cultivar displayed a lower degree of methylation. Therefore, the establishment of calcium-mediated linkages between cell wall polymers might have been favoured in 'Mondial Gala' apples, thus reinforcing tissues and improving the preservation of textural attributes, in comparison to 'Granny Smith' samples.

  16. A decision support system (GesCoN) for managing fertigation in open field vegetable crops. Part I—methodological approach and description of the software

    OpenAIRE

    Antonio eElia; Giulia eConversa

    2015-01-01

    Reduced water availability and environmental pollution caused by nitrogen (N) losses have increased the need for rational management of irrigation and N fertilization in horticultural systems. Decision support systems (DSS) could be powerful tools to assist farmers to improve irrigation and N fertilization efficiency. Currently, fertilization by drip irrigation system (fertigation) is used for many vegetable crops around the world. The paper illustrates the theoretical basis, the methodologic...

  17. A Methodological Approach to Assess the Impact of Smarting Action on Electricity Transmission and Distribution Networks Related to Europe 2020 Targets

    Directory of Open Access Journals (Sweden)

    Andrea Bonfiglio

    2017-01-01

    Full Text Available The achievement of the so-called 2020 targets requested by the European Union (EU has determined a significant growth of proposals of solutions and of technical projects aiming at reducing the CO2 emissions and increasing the energy efficiency, as well as the penetration of Renewable Energy Sources (RES in the electric network. As many of them ask for funding from the EU itself, there is the necessity to define a methodology to rank them and decide which projects should be sponsored to obtain the maximum effect on the EU 2020 targets. The present paper aims at (i defining a set of Key Performance Indicators (KPIs to compare different proposals, (ii proposing an analytical methodology to evaluate the defined KPIs and (iii evaluating the maximum impact that the considered action is capable of producing. The proposed methodology is applied to a set of possible interventions performed on a benchmark transmission network test case, in order to show that the defined indicators can be either calculated or measured and that they are useful to rank different “smarting actions”.

  18. Scoping studies: advancing the methodology

    Directory of Open Access Journals (Sweden)

    O'Brien Kelly K

    2010-09-01

    Full Text Available Abstract Background Scoping studies are an increasingly popular approach to reviewing health research evidence. In 2005, Arksey and O'Malley published the first methodological framework for conducting scoping studies. While this framework provides an excellent foundation for scoping study methodology, further clarifying and enhancing this framework will help support the consistency with which authors undertake and report scoping studies and may encourage researchers and clinicians to engage in this process. Discussion We build upon our experiences conducting three scoping studies using the Arksey and O'Malley methodology to propose recommendations that clarify and enhance each stage of the framework. Recommendations include: clarifying and linking the purpose and research question (stage one; balancing feasibility with breadth and comprehensiveness of the scoping process (stage two; using an iterative team approach to selecting studies (stage three and extracting data (stage four; incorporating a numerical summary and qualitative thematic analysis, reporting results, and considering the implications of study findings to policy, practice, or research (stage five; and incorporating consultation with stakeholders as a required knowledge translation component of scoping study methodology (stage six. Lastly, we propose additional considerations for scoping study methodology in order to support the advancement, application and relevance of scoping studies in health research. Summary Specific recommendations to clarify and enhance this methodology are outlined for each stage of the Arksey and O'Malley framework. Continued debate and development about scoping study methodology will help to maximize the usefulness and rigor of scoping study findings within healthcare research and practice.

  19. Prioritization methodology for chemical replacement

    Science.gov (United States)

    Goldberg, Ben; Cruit, Wendy; Schutzenhofer, Scott

    1995-01-01

    This methodology serves to define a system for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi quantitative approach derived from quality function deployment techniques (QFD Matrix). QFD is a conceptual map that provides a method of transforming customer wants and needs into quantitative engineering terms. This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives.

  20. Theory and Methodology in Researching Emotions in Education

    Science.gov (United States)

    Zembylas, Michalinos

    2007-01-01

    Differing theoretical approaches to the study of emotions are presented: emotions as private (psychodynamic approaches); emotions as sociocultural phenomena (social constructionist approaches); and a third perspective (interactionist approaches) transcending these two. These approaches have important methodological implications in studying…

  1. Literacy research methodologies

    CERN Document Server

    Duke, Nell K

    2012-01-01

    The definitive reference on literacy research methods, this book serves as a key resource for researchers and as a text in graduate-level courses. Distinguished scholars clearly describe established and emerging methodologies, discuss the types of questions and claims for which each is best suited, identify standards of quality, and present exemplary studies that illustrate the approaches at their best. The book demonstrates how each mode of inquiry can yield unique insights into literacy learning and teaching and how the methods can work together to move the field forward.   New to This Editi

  2. Reflections on methodological approaches and conceptual contributions in a program of caregiving research: development and testing of Wuest's theory of family caregiving.

    Science.gov (United States)

    Wuest, Judith; Hodgins, Marilyn J

    2011-02-01

    Caregiving by family members, particularly women, is a societal expectation that is intensifying in the context of an aging population and health care restructuring. Our program of caregiving research spans two decades, moving from inductive theory development using grounded theory methods to deductive theory testing. In this article, we reflect on the serendipitous development of this program of research methodologically and conceptually. We summarize the key conceptual contributions that the program has made to caregiving knowledge, particularly with respect to the past relationship between care recipient and caregiver, obligation to care, caregiver agency, and relationships between caregivers and the health care system.

  3. THE FUTURE OF LANGUAGE TEACHING METHODOLOGY

    OpenAIRE

    Ted Rodgers

    1998-01-01

    Abstract : This paper reviews the current state of ELT methodology, particulary in respect to a number of current views suggesting that the profession is now in a "post-methods" era in which previous attention to Methods (Total Physical Response, Silent Way, Natural Approach, etc.) has given way to a more generic approach to ELT methodology. Ten potential future courses of ELT methodology are outlines and three of these are considered in some detail. Particular consideration is given as to ho...

  4. Grounded theory methodology--narrativity revisited.

    Science.gov (United States)

    Ruppel, Paul Sebastian; Mey, Günter

    2015-06-01

    This article aims to illuminate the role of narrativity in Grounded Theory Methodology and to explore an approach within Grounded Theory Methodology that is sensitized towards aspects of narrativity. The suggested approach takes into account narrativity as an aspect of the underlying data. It reflects how narrativity could be conceptually integrated and systematically used for shaping the way in which coding, category development and the presentation of results in a Grounded Theory Methodology study proceed.

  5. Methodological approach for substantiating disease freedom in a heterogeneous small population. Application to ovine scrapie, a disease with a strong genetic susceptibility.

    Science.gov (United States)

    Martinez, Marie-José; Durand, Benoit; Calavas, Didier; Ducrot, Christian

    2010-06-01

    Demonstrating disease freedom is becoming important in different fields including animal disease control. Most methods consider sampling only from a homogeneous population in which each animal has the same probability of becoming infected. In this paper, we propose a new methodology to calculate the probability of detecting the disease if it is present in a heterogeneous population of small size with potentially different risk groups, differences in risk being defined using relative risks. To calculate this probability, for each possible arrangement of the infected animals in the different groups, the probability that all the animals tested are test-negative given this arrangement is multiplied by the probability that this arrangement occurs. The probability formula is developed using the assumption of a perfect test and hypergeometric sampling for finite small size populations. The methodology is applied to scrapie, a disease affecting small ruminants and characterized in sheep by a strong genetic susceptibility defining different risk groups. It illustrates that the genotypes of the tested animals influence heavily the confidence level of detecting scrapie. The results present the statistical power for substantiating disease freedom in a small heterogeneous population as a function of the design prevalence, the structure of the sample tested, the structure of the herd and the associated relative risks.

  6. A methodological approach to the study of archaeological cereal meals: a case study at Çatalhöyük East (Turkey).

    Science.gov (United States)

    González Carretero, Lara; Wollstonecroft, Michèle; Fuller, Dorian Q

    2017-01-01

    This paper presents an integrated methodology for the analysis of archaeological remains of cereal meals, based on scanning electronic microscopic analyses of microstructures of charred food fragments from Neolithic Çatalhöyük (Turkey). The remains of cereal foods as 'bread-like' or 'porridge-like' small charred lumps of various amalgamated plant materials are frequently recovered from Neolithic and later archaeological sites in southwest Asia and Europe. Cereal food remains have recently attracted interest because the identification of their plant contents, the forms of food that they represent and the methods used in their creation can provide unique information about ancient culinary traditions and routine food processing, preparation and cooking techniques. Here, we focus on three methodological aspects: (1) the analysis of their composition; (2) the analysis of their microstructure to determine preparation and cooking processes; (3) the comparison with experimental reference materials. Preliminary results are presented on the botanical composition and cooking processes represented by the charred cereal preparations found at Neolithic Çatalhöyük (Turkey), for example cereals processed into bread, dough and/or porridge.

  7. METODOLOGÍA DE DISEÑO ORGANIZACIONAL INTEGRANDO ENFOQUE A PROCESOS Y COMPETENCIAS / METHODOLOGY OF ORGANIZATIONAL DESIGN INTEGRATING PROCESS APPROACH AND COMPETENCIES

    Directory of Open Access Journals (Sweden)

    Iraida Justina Rodríguez-González

    2012-04-01

    Full Text Available La Metodología de Diseño Organizacional responde a la introducción de formas organizativas basadas en el diseño de procesos, la estrategia y la gestión por competencias; integradas con los sistemas y tecnologías de la información. El modelo de diseño tiene como objetivo fundamental brindar una herramienta que permita diseñar una organización de nueva creación al tiempo que se va construyendo, sustentado en una plataforma integrada. La aplicación realizada en el Complejo de Investigaciones Tecnológicas Integradas (CITI demuestra la factibilidad de la metodología en las condiciones actuales y los resultados obtenidos avalan los procedimientos que la hacen funcional para Cuba y adaptable a objetivos similares en otros países.AbstractThe Methodology of Organizational Design corresponds to the introduction of organizational forms based on process design, strategy and management by competencies, which are integrated with the systems and information technologies. The design model aims to provide a tool to design a new organization while it is constructed, based on an integrated platform. The application carried out in the Complex of Integrated Technological Investigations (CITI, in its Spanish acronym, demonstrates the feasibility of the methodology under the current conditions and the obtained results endorse the procedures that make it functional for Cuba and adaptable to similar objectives in other countries.

  8. 案例教学对英语教学论课程教学的启示%Implications of Case Study Approach to the Teaching of English Language Teaching Methodology

    Institute of Scientific and Technical Information of China (English)

    蔡红梅; 潘景丽

    2011-01-01

    案例教学有利于教师和学生角色的转变、学生知识来源的扩大、学习内容的优化、学习效果的改善,以及学生能力的提高。在英语教学论课程教学中实施案例教学有利于提高英语教学论课程的教学效果,为培养合格的基础教育英语师资奠定了很好的基础。%Based on the understanding of the concept and major features of case study approach, this paper points out the advantages of applying case study approach in the teaching of English Language Teaching Methodology, that is, case study ap- proach can help to change both teacher' s and students' roles, to expand students' knowledge sources, to refine the learning contents, and to improve the learning effectiveness of the course and students' various abilities. Applying case study approach can improve the effectiveness of ELT Methodology teaching and lay a good foundation for the nurturing of qualified English teachers of Basic Education.

  9. Tool flank wear model and parametric optimization in end milling of metal matrix composite using carbide tool: Response surface methodology approach

    Directory of Open Access Journals (Sweden)

    R. Arokiadass

    2012-04-01

    Full Text Available Highly automated CNC end milling machines in manufacturing industry requires reliable model for prediction of tool flank wear. This model later can be used to predict the tool flank wear (VBmax according to the process parameters. In this investigation an attempt was made to develop an empirical relationship to predict the tool flank wear (VBmax of carbide tools while machining LM25 Al/SiCp incorporating the process parameters such as spindle speed (N, feed rate (f, depth of cut (d and various % wt. of silicon carbide (S. Response surface methodology (RSM was applied to optimizing the end milling process parameters to attain the minimum tool flank wear. Predicted values obtained from the developed model and experimental results are compared, and error <5 percent is observed. In addition, it is concluded that the flank wear increases with the increase of SiCp percentage weight in the MMC.

  10. Aerial Photogrammetry by drone in archaeological sites with large structures. Methodological approach and practical application in the medieval castles of Campo de Montiel

    Directory of Open Access Journals (Sweden)

    Juan Ángel Ruiz Sabina

    2015-11-01

    Full Text Available By writing this article we aim to illustrate the interesting combination of two existing techniques, accessible both for research groups and for professionals who want to study archaeological heritage: photogrammetry and aerial photography using a drone. We have applied these techniques to archaeological sites with standing structures, such as medieval castles in “Campo de Montiel” (Ciudad Real. Based on our expertise and experience, we have developed methodology for surface archaeological research, excavation and wall stratigraphy, thus identifying positive and negative aspects of this ethodology. The results obtained are truly positive, as we generated high-quality images offering news opportunities to investigate and show results, saving a considerable amount of time and money compared to traditional methods for graphical documentation.

  11. An Integrated Modeling Approach for Predicting Process Maps of Residual Stress and Distortion in a Laser Weld: A Combined CFD-FE Methodology

    Science.gov (United States)

    Turner, Richard P.; Panwisawas, Chinnapat; Sovani, Yogesh; Perumal, Bama; Ward, R. Mark; Brooks, Jeffery W.; Basoalto, Hector C.

    2016-10-01

    Laser welding has become an important joining methodology within a number of industries for the structural joining of metallic parts. It offers a high power density welding capability which is desirable for deep weld sections, but is equally suited to performing thinner welded joints with sensible amendments to key process variables. However, as with any welding process, the introduction of severe thermal gradients at the weld line will inevitably lead to process-induced residual stress formation and distortions. Finite element (FE) predictions for weld simulation have been made within academia and industrial research for a number of years, although given the fluid nature of the molten weld pool, FE methodologies have limited capabilities. An improvement upon this established method would be to incorporate a computational fluid dynamics (CFD) model formulation prior to the FE model, to predict the weld pool shape and fluid flow, such that details can be fed into FE from CFD as a starting condition. The key outputs of residual stress and distortions predicted by the FE model can then be monitored against the process variables input to the model. Further, a link between the thermal results and the microstructural properties is of interest. Therefore, an empirical relationship between lamellar spacing and the cooling rate was developed and used to make predictions about the lamellar spacing for welds of different process parameters. Processing parameter combinations that lead to regions of high residual stress formation and high distortion have been determined, and the impact of processing parameters upon the predicted lamellar spacing has been presented.

  12. An approach to holistically assess (dairy) farm eco-efficiency by combining Life Cycle Analysis with Data Envelopment Analysis models and methodologies.

    Science.gov (United States)

    Soteriades, A D; Faverdin, P; Moreau, S; Charroin, T; Blanchard, M; Stott, A W

    2016-11-01

    Eco-efficiency is a useful guide to dairy farm sustainability analysis aimed at increasing output (physical or value added) and minimizing environmental impacts (EIs). Widely used partial eco-efficiency ratios (EIs per some functional unit, e.g. kg milk) can be problematic because (i) substitution possibilities between EIs are ignored, (ii) multiple ratios can complicate decision making and (iii) EIs are not usually associated with just the functional unit in the ratio's denominator. The objective of this study was to demonstrate a 'global' eco-efficiency modelling framework dealing with issues (i) to (iii) by combining Life Cycle Analysis (LCA) data and the multiple-input, multiple-output production efficiency method Data Envelopment Analysis (DEA). With DEA each dairy farm's outputs and LCA-derived EIs are aggregated into a single, relative, bounded, dimensionless eco-efficiency score, thus overcoming issues (i) to (iii). A novelty of this study is that a model providing a number of additional desirable properties was employed, known as the Range Adjusted Measure (RAM) of inefficiency. These properties altogether make RAM advantageous over other DEA models and are as follows. First, RAM is able to simultaneously minimize EIs and maximize outputs. Second, it indicates which EIs and/or outputs contribute the most to a farm's eco-inefficiency. Third it can be used to rank farms in terms of eco-efficiency scores. Thus, non-parametric rank tests can be employed to test for significant differences in terms of eco-efficiency score ranks between different farm groups. An additional DEA methodology was employed to 'correct' the farms' eco-efficiency scores for inefficiencies attributed to managerial factors. By removing managerial inefficiencies it was possible to detect differences in eco-efficiency between farms solely attributed to uncontrollable factors such as region. Such analysis is lacking in previous dairy studies combining LCA with DEA. RAM and the 'corrective

  13. On the Application of Case-based Teaching Approach in Primary Mathematics Teaching Methodology in Higher Normal Colleges%案例教学法在高师院校小学数学教法课中的运用

    Institute of Scientific and Technical Information of China (English)

    张黎黎

    2014-01-01

    案例教学法运用于高师院校的小学数学教法课中可凸显教法课的特色,将以往课堂上的被动式学习变为了主动式学习,使课堂气氛变得活跃起来,激发了学员的学习兴趣,而且使学员主动地学习。同时,案例教学法也对教师提出了更高的要求,本文作者结合自身多年的从教经验对案例教学法的涵义、实施方法及存在的问题进行了相关分析,具体如下文所示。%The application of case-based teaching approach in primary mathematics teaching methodology in higher normal col-leges can highlight the characteristics of teaching methodology courses, changing the former passive learning to active learning in class, activating classroom atmosphere, stimulating students' learning interest and promoting students' autonomous learning, but it has also proposed higher requirements for teachers. Com-bined with the writer's years of teaching experience, relevant analyses on the connotation, implementation methods and exist-ing problems of case-based teaching approach are made specifi-cally in this paper.

  14. Differing antidepressant maintenance methodologies.

    Science.gov (United States)

    Safer, Daniel J

    2017-10-01

    The principle evidence that antidepressant medication (ADM) is an effective maintenance treatment for adults with major depressive disorder (MDD) is from placebo substitution trials. These trials enter responders from ADM efficacy trials into randomized, double-blind placebo-controlled (RDBPC) effectiveness trials to measure the rate of MDD relapse over time. However, other randomized maintenance trial methodologies merit consideration and comparison. A systematic review of ADM randomized maintenance trials included research reports from multiple databases. Relapse rate was the main effectiveness outcome assessed. Five ADM randomized maintenance methodologies for MDD responders are described and compared for outcome. These effectiveness trials include: placebo-substitution, ADM/placebo extension, ADM extension, ADM vs. psychotherapy, and treatment as usual. The placebo-substitution trials for those abruptly switched to placebo resulted in unusually high (46%) rates of relapse over 6-12months, twice the continuing ADM rate. These trials were characterized by selective screening, high attrition, an anxious anticipation of a switch to placebo, and a risk of drug withdrawal symptoms. Selectively screened ADM efficacy responders who entered into 4-12month extension trials experienced relapse rates averaging ~10% with a low attrition rate. Non-industry sponsored randomized trials of adults with multiple prior MDD episodes who were treated with ADM maintenance for 1-2years experienced relapse rates averaging 40%. Placebo substitution trial methodology represents only one approach to assess ADM maintenance. Antidepressant maintenance research for adults with MDD should be evaluated for industry sponsorship, attrition, the impact of the switch to placebo, and major relapse differences in MDD subpopulations. Copyright © 2017. Published by Elsevier Inc.

  15. A methodological approach for deriving regional crop rotations as basis for the assessment of the impact of agricultural strategies using soil erosion as example.

    Science.gov (United States)

    Lorenz, Marco; Fürst, Christine; Thiel, Enrico

    2013-09-01

    Regarding increasing pressures by global societal and climate change, the assessment of the impact of land use and land management practices on land degradation and the related decrease in sustainable provision of ecosystem services gains increasing interest. Existing approaches to assess agricultural practices focus on the assessment of single crops or statistical data because spatially explicit information on practically applied crop rotations is mostly not available. This provokes considerable uncertainties in crop production models as regional specifics have to be neglected or cannot be considered in an appropriate way. In a case study in Saxony, we developed an approach to (i) derive representative regional crop rotations by combining different data sources and expert knowledge. This includes the integration of innovative crop sequences related to bio-energy production or organic farming and different soil tillage, soil management and soil protection techniques. Furthermore, (ii) we developed a regionalization approach for transferring crop rotations and related soil management strategies on the basis of statistical data and spatially explicit data taken from so called field blocks. These field blocks are the smallest spatial entity for which agricultural practices must be reported to apply for agricultural funding within the frame of the European Agricultural Fund for Rural Development (EAFRD) program. The information was finally integrated into the spatial decision support tool GISCAME to assess and visualize in spatially explicit manner the impact of alternative agricultural land use strategies on soil erosion risk and ecosystem services provision. Objective of this paper is to present the approach how to create spatially explicit information on agricultural management practices for a study area around Dresden, the capital of the German Federal State Saxony.

  16. An Approach Based on TRIZ Methodology and SERVQUAL Scale to Improve the Quality of Health-Care Service: A Case Study

    OpenAIRE

    2012-01-01

    A new innovative approach based on theory of inventive problem solving (TRIZ) and the quality service measurement scale (SERVQUAL) is proposed to improve the quality of health-care service. TRIZ is used at a wide range of area in industrialized countries to solve problems, while SERVQUAL is used very extensively to measure quality of service sector (especially in health-care service) by many researchers. Su et al. (2008) proposed a systematic framework based on TRIZ to solve the service quali...

  17. A Methodological Approach to Assessing the Health Impact of Environmental Chemical Mixtures: PCBs and Hypertension in the National Health and Nutrition Examination Survey

    Directory of Open Access Journals (Sweden)

    Paul White

    2011-11-01

    Full Text Available We describe an approach to examine the association between exposure to chemical mixtures and a health outcome, using as our case study polychlorinated biphenyls (PCBs and hypertension. The association between serum PCB and hypertension among participants in the 1999–2004 National Health and Nutrition Examination Survey was examined. First, unconditional multivariate logistic regression was used to estimate odds ratios and associated 95% confidence intervals. Next, correlation and multicollinearity among PCB congeners was evaluated, and clustering analyses performed to determine groups of related congeners. Finally, a weighted sum was constructed to represent the relative importance of each congener in relation to hypertension risk. PCB serum concentrations varied by demographic characteristics, and were on average higher among those with hypertension. Logistic regression results showed mixed findings by congener and class. Further analyses identified groupings of correlated PCBs. Using a weighted sum approach to equalize different ranges and potencies, PCBs 66, 101, 118, 128 and 187 were significantly associated with increased risk of hypertension. Epidemiologic data were used to demonstrate an approach to evaluating the association between a complex environmental exposure and health outcome. The complexity of analyzing a large number of related exposures, where each may have different potency and range, are addressed in the context of the association between hypertension risk and exposure to PCBs.

  18. A methodological approach to assessing the health impact of environmental chemical mixtures: PCBs and hypertension in the National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Yorita Christensen, Krista L; White, Paul

    2011-11-01

    We describe an approach to examine the association between exposure to chemical mixtures and a health outcome, using as our case study polychlorinated biphenyls (PCBs) and hypertension. The association between serum PCB and hypertension among participants in the 1999-2004 National Health and Nutrition Examination Survey was examined. First, unconditional multivariate logistic regression was used to estimate odds ratios and associated 95% confidence intervals. Next, correlation and multicollinearity among PCB congeners was evaluated, and clustering analyses performed to determine groups of related congeners. Finally, a weighted sum was constructed to represent the relative importance of each congener in relation to hypertension risk. PCB serum concentrations varied by demographic characteristics, and were on average higher among those with hypertension. Logistic regression results showed mixed findings by congener and class. Further analyses identified groupings of correlated PCBs. Using a weighted sum approach to equalize different ranges and potencies, PCBs 66, 101, 118, 128 and 187 were significantly associated with increased risk of hypertension. Epidemiologic data were used to demonstrate an approach to evaluating the association between a complex environmental exposure and health outcome. The complexity of analyzing a large number of related exposures, where each may have different potency and range, are addressed in the context of the association between hypertension risk and exposure to PCBs.

  19. 从“三论”角度来看商务外语的发展%Business Foreign Language:Ontological, Epistemological and Methodological Approaches

    Institute of Scientific and Technical Information of China (English)

    王铭玉

    2013-01-01

    China’s ever-quickening pace of economic reform and opening up is increasingly foregrounding the importance of “Business Foreign Language” (BFL), some critical issues of which are now under intensified discussion. Relevant surveys reveal BFL as still problematic despite the fact that its predominant branch-“Business English” has gained much recognition in the area of foreign language teaching in China. From an ontological perspective, BFL, for its very existence, demands a clearer deifnition regarding terminology, disciplinary position, theoretical system, education model, and its entry into the Discipline Catalogue. From an epistemological perspective, BFL entails stronger theoretical conifrmation especially in its relation to semiotics, functionalism and constructivism. And from a methodological perspective, BFL requires further studies in terms of teaching, research and teaching-learning relationship. As a burgeoning discipline, BFL calls for intensive and extensive studies based on an appropriate and efifcient methodology.%随着我国经济改革和对外开放进程的加速发展,商务外语的重要作用愈加凸显。与之相适应,外语学界加大了对商务外语的研究力度,展开了对一系列相关紧要问题的探讨。调查表明,虽然商务英语在我国教学领域已成气候,但就整个商务外语而言,亟待解决的难题还很多。从本体论来看,涉及商务外语生存的术语概念、学科地位、培养模式、理论体系、专业目录等问题还需进一步确定;从认识论来看,商务外语的理论构建尚需加强,它与符号学说、功能主义、建构主义等学说的关系还有进一步求证的空间;从方法论来看,在教学方法、教学关系、科学研究等方面还有进一步研讨的必要。商务外语是一个新兴的专业和学科方向,正确的引导和全方位的研究必将极大地促进这一新生事物的健康发展。

  20. Improving the Spatial Prediction of Soil Organic Carbon Stocks in a Complex Tropical Mountain Landscape by Methodological Specifications in Machine Learning Approaches.

    Science.gov (United States)

    Ließ, Mareike; Schmidt, Johannes; Glaser, Bruno

    2016-01-01

    Tropical forests are significant carbon sinks and their soils' carbon storage potential is immense. However, little is known about the soil organic carbon (SOC) stocks of tropical mountain areas whose complex soil-landscape and difficult accessibility pose a challenge to spatial analysis. The choice of methodology for spatial prediction is of high importance to improve the expected poor model results in case of low predictor-response correlations. Four aspects were considered to improve model performance in predicting SOC stocks of the organic layer of a tropical mountain forest landscape: Different spatial predictor settings, predictor selection strategies, various machine learning algorithms and model tuning. Five machine learning algorithms: random forests, artificial neural networks, multivariate adaptive regression splines, boosted regression trees and support vector machines were trained and tuned to predict SOC stocks from predictors derived from a digital elevation model and satellite image. Topographical predictors were calculated with a GIS search radius of 45 to 615 m. Finally, three predictor selection strategies were applied to the total set of 236 predictors. All machine learning algorithms-including the model tuning and predictor selection-were compared via five repetitions of a tenfold cross-validation. The boosted regression tree algorithm resulted in the overall best model. SOC stocks ranged between 0.2 to 17.7 kg m-2, displaying a huge variability with diffuse insolation and curvatures of different scale guiding the spatial pattern. Predictor selection and model tuning improved the models' predictive performance in all five machine learning algorithms. The rather low number of selected predictors favours forward compared to backward selection procedures. Choosing predictors due to their indiviual performance was vanquished by the two procedures which accounted for predictor interaction.

  1. Application of a GIS-/remote sensing-based approach for predicting groundwater potential zones using a multi-criteria data mining methodology.

    Science.gov (United States)

    Mogaji, Kehinde Anthony; Lim, Hwee San

    2017-07-01

    This study integrates the application of Dempster-Shafer-driven evidential belief function (DS-EBF) methodology with remote sensing and geographic information system techniques to analyze surface and subsurface data sets for the spatial prediction of groundwater potential in Perak Province, Malaysia. The study used additional data obtained from the records of the groundwater yield rate of approximately 28 bore well locations. The processed surface and subsurface data produced sets of groundwater potential conditioning factors (GPCFs) from which multiple surface hydrologic and subsurface hydrogeologic parameter thematic maps were generated. The bore well location inventories were partitioned randomly into a ratio of 70% (19 wells) for model training to 30% (9 wells) for model testing. Application results of the DS-EBF relationship model algorithms of the surface- and subsurface-based GPCF thematic maps and the bore well locations produced two groundwater potential prediction (GPP) maps based on surface hydrologic and subsurface hydrogeologic characteristics which established that more than 60% of the study area falling within the moderate-high groundwater potential zones and less than 35% falling within the low potential zones. The estimated uncertainty values within the range of 0 to 17% for the predicted potential zones were quantified using the uncertainty algorithm of the model. The validation results of the GPP maps using relative operating characteristic curve method yielded 80 and 68% success rates and 89 and 53% prediction rates for the subsurface hydrogeologic factor (SUHF)- and surface hydrologic factor (SHF)-based GPP maps, respectively. The study results revealed that the SUHF-based GPP map accurately delineated groundwater potential zones better than the SHF-based GPP map. However, significant information on the low degree of uncertainty of the predicted potential zones established the suitability of the two GPP maps for future development of

  2. Rationale, design and methodology for Intraventricular Pressure Gradients Study: a novel approach for ventricular filling assessment in normal and falling hearts

    Directory of Open Access Journals (Sweden)

    Vouga Luís

    2011-05-01

    . Discussion We expect to validate the application of our method to obtain intraventricular pressure gradients in animals and patients and to promote a methodology to better understand the ventricular relaxation and filling and their correlation with systolic function.

  3. A Q-Methodology approach to investigating the relationship between level of reflection and typologies among prospective teachers in the physics learning assistant program at Florida International University

    Science.gov (United States)

    Cochran, Geraldine L.

    The purpose of this mixed methods study was to understand physics Learning Assistants' (LAs) views on reflective teaching, expertise in teaching, and LA program teaching experience and to determine if views predicted level of reflection evident in writing. Interviews were conducted in Phase One, Q methodology was used in Phase Two, and level of reflection in participants' writing was assessed using a rubric based on Hatton and Smith's (1995) "Criteria for the Recognition of Evidence for Different Types of Reflective Writing" in Phase Three. Interview analysis revealed varying perspectives on content knowledge, pedagogical knowledge, and experience in relation to expertise in teaching. Participants revealed that they engaged in reflection on their teaching, believed reflection helps teachers improve, and found peer reflection beneficial. Participants believed teaching experience in the LA program provided preparation for teaching, but that more preparation was needed to teach. Three typologies emerged in Phase Two. Type One LAs found participation in the LA program rewarding and believed expertise in teaching does not require expertise in content or pedagogy, but it develops over time from reflection. Type Two LAs valued reflection, but not writing reflections, felt the LA program teaching experience helped them decide on non-teaching careers and helped them confront gaps in their physics knowledge. Type Three LAs valued reflection, believed expertise in content and pedagogy are necessary for expert teaching, and felt LA program teaching experience increased their likelihood of becoming teachers, but did not prepare them for teaching. Writing assignments submitted in Phase Three were categorized as 19% descriptive writing, 60% descriptive reflections, and 21% dialogic reflections. No assignments were categorized as critical reflection. Using ordinal logistic regression, typologies that emerged in Phase Two were not found to be predictors for the level of reflection

  4. Constructivism: a naturalistic methodology for nursing inquiry.

    Science.gov (United States)

    Appleton, J V; King, L

    1997-12-01

    This article will explore the philosophical underpinnings of the constructivist research paradigm. Despite its increasing popularity in evaluative health research studies there is limited recognition of constructivism in popular research texts. Lincoln and Guba's original approach to constructivist methodology is outlined and a detailed framework for nursing research is offered. Fundamental issues and concerns surrounding this methodology are debated and differences between method and methodology are highlighted.

  5. Methodological pluralism and narrative inquiry

    Science.gov (United States)

    Michie, Michael

    2013-09-01

    This paper considers how the integral theory model of Nancy Davis and Laurie Callihan might be enacted using a different qualitative methodology, in this case the narrative methodology. The focus of narrative research is shown to be on `what meaning is being made' rather than `what is happening here' (quadrant 2 rather than quadrant 1). It is suggested that in using the integral theory model, a qualitative research project focuses primarily on one quadrant and is enhanced by approaches suggested in the other quadrants.

  6. Climate change and Development of a methodological approach for the implementation of a strategy of resilience in the face of floods (Tangier North of Morocco)

    Science.gov (United States)

    Satour, N.; Kassou, N.; Kacimi, I.; BEN-Daoud, M.; Maatouk, M.

    2016-12-01

    Tangier is one of the 14 priority cities, cited in the National Plan for the fight against the floods in Morocco with the specifics linked to its geographical position and socio-economic factors. The city needs more strategies to improve it response and confidence in front of floods risk. Climate change exacerbates this problem by causing more frequent extreme precipitation events. Several different traditional methods were used to modelling, understanding and anticipating the phenomenon but the urban resilience is studied by few authors in Morocco. The approach should uncover the role of all components of the urban system, economic, institutional and natural. The central aim of this study is to develop a new resilience strategy of urban system of Tangier to floods across temporal and spatial scales to maintain or rapidly return to desired functions in the face of disturbance to adapt to change, and to quickly transform systems that limit current or future adaptive capacity. The Flood resilience index (FRI) is developed as an approach for evaluation of flood resilience using Geographic Information Systems. The research for this study started from the findings and conclusion of Meerow, Sara. 2016 and Batica, Jelena 2015. . Here we seek to introduce the factor "Climate Change" in the forecast scenarios of the resilience of the city by 2030. This suggests additional thinks about flood risks and adaptation strategies in Morocco.

  7. Methodological basis of training of musically gifted student

    OpenAIRE

    Полубоярина, Ірина Іванівна

    2015-01-01

    Methodological bases of problem of professional training of musically gifted students are investigated. It is established that at the level of general scientific methodology the problem of training involves an appeal to a synergistic, systemic, humanistic and active approaches. The study of the problem at the level of specifically scientific methodology was carried out on the basis of acmeological, axiological, facilitating and hermeneutical approaches

  8. Hamlet, Macbeth, Othello and King Lear in the English Teaching at School: a methodological approach - doi: 10.4025/actascieduc.v34i2.15070

    Directory of Open Access Journals (Sweden)

    Valdomiro Polidório

    2012-11-01

    Full Text Available In this article we will talk about the relevance of dramatic texts in schools. Therefore we will approach the tragedies Hamlet, Macbeth, Otelo e King Lear de William Shakespeare and how teachers can explore them as a help in the teaching of languages without forgetting that they are dramatic and literary texts. When we refer to languages, we want to say any language, because Shakespearean texts are ageless, may have many meanings and deal with human nature. The theatre is in our lives and in this case it is relevant to quote William Shakespeare himself that said that “life is a stage and we are actors”. Starting from this, we will consider the best ways of using the tragedies Hamlet, Macbeth, Otelo e King Lear in the classroom.  

  9. Exploring the use of grounded theory as a methodological approach to examine the 'black box' of network leadership in the national quality forum.

    Science.gov (United States)

    Hoflund, A Bryce

    2013-01-01

    This paper describes how grounded theory was used to investigate the "black box" of network leadership in the creation of the National Quality Forum. Scholars are beginning to recognize the importance of network organizations and are in the embryonic stages of collecting and analyzing data about network leadership processes. Grounded theory, with its focus on deriving theory from empirical data, offers researchers a distinctive way of studying little-known phenomena and is therefore well suited to exploring network leadership processes. Specifically, this paper provides an overview of grounded theory, a discussion of the appropriateness of grounded theory to investigating network phenomena, a description of how the research was conducted, and a discussion of the limitations and lessons learned from using this approach.

  10. A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis.

    Science.gov (United States)

    Kirkham, Jamie J; Clarke, Mike; Williamson, Paula R

    2017-05-17

    Objective To assess the uptake of the rheumatoid arthritis core outcome set using a new assessment method of calculating uptake from data in clinical trial registry entries.Design Review of randomised trials.Setting ClinicalTrials.gov.Subjects 273 randomised trials of drug interventions for the treatment of rheumatoid arthritis and registered in ClinicalTrials.gov between 2002 and 2016. Full publications were identified for completed studies from information in the trial registry or from an internet search using Google and the citation database Web of Science.Main outcome measure The percentage of trials reporting or planning to measure the rheumatoid arthritis core outcome set calculated from the information presented in the trial registry and compared with the percentage reporting the rheumatoid arthritis core outcome set in the resulting trial publications.Results The full rheumatoid arthritis core outcome set was reported in 81% (116/143) of trials identified on the registry as completed (or terminated) for which results were found in either the published literature or the registry. For trials identified on the registry as completed (or terminated), using information only available in the registry gives an estimate for uptake of 77% (145/189).Conclusions The uptake of the rheumatoid arthritis core outcome set in clinical trials has continued to increase over time. Using the information on outcomes listed for completed or terminated studies in a trial registry provides a reasonable estimate of the uptake of a core outcome set and is a more efficient and up-to-date approach than examining the outcomes in published trial reports. The method proposed may provide an efficient approach for an up-to-date assessment of the uptake of the 300 core outcome sets already published. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  11. Programa educativo em esquistossomose: modelo de abordagem metodológica Educational program in schistosomiasis: a model for a methodological approach

    Directory of Open Access Journals (Sweden)

    Patrícia de Jesus Ribeiro

    2004-06-01

    schistosomiasis patients (groups 2 and 3, with 20 individuals in each group. Teaching material (illustrated manual and album of leaflets and a questionnaire consisting of 17 questions to evaluate the groups' knowledge were devised. The questionnaire was applied to groups 1 and 2 before and to group 3 after the educational program. The variables studied were the educational program, level of schooling, age, clinical form of schistosomiasis, symptoms, and the subject's performance when answering the questionnaire. For the statistical analysis, Fisher's exact test and variance analysis with one fixed factor were utilized. RESULTS: The educational program was evaluated in the form of four topics: cycle, clinical presentation, treatment and prevention of the disease. The median number of correct responses to the questionnaire was higher for group 3 than for groups 1 and 2, for all the topics dealt with. This median was also higher for group 2 than for group 1, for all topics except for the item "prevention". CONCLUSIONS: The educational process applied was efficient and improved the knowledge of the disease. It may provide an effective low-cost methodological model that can also be applied to combating other endemic diseases.

  12. Language Teaching Methodology. ERIC Issue Paper.

    Science.gov (United States)

    Rodgers, Theodore S.

    This paper gives an overview of 10 directions language teachers might take in the future. After providing background on the history of language teaching, language teaching methodology is defined and a distinction is made between methodologies and approaches. Next, the 10 scenarios are briefly described. They include the following: teacher/learner…

  13. Embodied Writing: Choreographic Composition as Methodology

    Science.gov (United States)

    Ulmer, Jasmine B.

    2015-01-01

    This paper seeks to examine how embodied methodological approaches might inform dance education practice and research. Through a series of examples, this paper explores how choreographic writing might function as an embodied writing methodology. Here, choreographic writing is envisioned as a form of visual word choreography in which words move,…

  14. Grounded Theory Methodology: Positivism, Hermeneutics, and Pragmatism

    Science.gov (United States)

    Age, Lars-Johan

    2011-01-01

    Glaserian grounded theory methodology, which has been widely adopted as a scientific methodology in recent decades, has been variously characterised as "hermeneutic" and "positivist." This commentary therefore takes a different approach to characterising grounded theory by undertaking a comprehensive analysis of: (a) the philosophical paradigms of…

  15. Improving Learning Outcome Using Six Sigma Methodology

    Science.gov (United States)

    Tetteh, Godson A.

    2015-01-01

    Purpose: The purpose of this research paper is to apply the Six Sigma methodology to identify the attributes of a lecturer that will help improve a student's prior knowledge of a discipline from an initial "x" per cent knowledge to a higher "y" per cent of knowledge. Design/methodology/approach: The data collection method…

  16. IMPROVEMENT METHODOLOGY FINANCIAL RISK-MANAGEMENT

    OpenAIRE

    E. Kachalova

    2016-01-01

    The article examines the vital issues of improvement methodology financial risk-management. The author reveals the economic essence of the concept of «financial risk-management». Methodological approaches for the efficient management of risks in the system of risk-management in Russia.

  17. Discipline and Methodology in Higher Education Research

    Science.gov (United States)

    Tight, Malcolm

    2013-01-01

    Higher education research is a multidisciplinary field, engaging researchers from across the academy who make use of a wide range of methodological approaches. This article examines the relation between discipline and methodology in higher education research, analysing a database of 567 articles published in 15 leading higher education journals…

  18. Improving Learning Outcome Using Six Sigma Methodology

    Science.gov (United States)

    Tetteh, Godson A.

    2015-01-01

    Purpose: The purpose of this research paper is to apply the Six Sigma methodology to identify the attributes of a lecturer that will help improve a student's prior knowledge of a discipline from an initial "x" per cent knowledge to a higher "y" per cent of knowledge. Design/methodology/approach: The data collection method…

  19. Systematic Review Methodology in Higher Education

    Science.gov (United States)

    Bearman, Margaret; Smith, Calvin D.; Carbone, Angela; Slade, Susan; Baik, Chi; Hughes-Warrington, Marnie; Neumann, David L.

    2012-01-01

    Systematic review methodology can be distinguished from narrative reviews of the literature through its emphasis on transparent, structured and comprehensive approaches to searching the literature and its requirement for formal synthesis of research findings. There appears to be relatively little use of the systematic review methodology within the…

  20. Health-Related Coping and Social Interaction in People with Multiple Sclerosis Supported by a Social Network: Pilot Study With a New Methodological Approach.

    Science.gov (United States)

    Lavorgna, Luigi; Russo, Antonio; De Stefano, Manuela; Lanzillo, Roberta; Esposito, Sabrina; Moshtari, Fatemeh; Rullani, Francesco; Piscopo, Kyrie; Buonanno, Daniela; Brescia Morra, Vincenzo; Gallo, Antonio; Tedeschi, Gioacchino; Bonavita, Simona

    2017-07-14

    Social media are a vital link for people with health concerns who find in Web communities a valid and comforting source for information exchange, debate, and knowledge enrichment. This aspect is important for people affected by chronic diseases like multiple sclerosis (MS), who are very well informed about the disease but are vulnerable to hopes of being cured or saved by therapies whose efficacy is not always scientifically proven. To improve health-related coping and social interaction for people with MS, we created an MS social network (SMsocialnetwork.com) with a medical team constantly online to intervene promptly when false or inappropriate medical information are shared. The goal of this study was to assess the impact of SMsocialnetwork.com on the health-related coping and social interaction of people with MS by analyzing areas of interest through a Web-based survey. Referring to previous marketing studies analyzing the online platform's role in targeted health care, we conducted a 39-item Web-based survey. We then performed a construct validation procedure using a factorial analysis, gathering together like items of the survey related to different areas of interest such as utility, proximity, sharing, interaction, solving uncertainty, suggestion attitude, and exploration. We collected 130 Web-based surveys. The areas of interest analysis demonstrated that the users positively evaluated SMsocialnetwork.com to obtain information, approach and solve problems, and to make decisions (utility: median 4.2); improve feeling of closeness (proximity: median 5); catalyze relationships and text general personal opinions (sharing: median 5.6); get in touch with other users to receive innovative, effective, and practical solutions (interaction, solving uncertainty, and suggestion attitude medians were respectively: 4.1, 3, and 3); and share information about innovative therapeutic approaches and treatment options (suggestion attitude: median: 3.3). SMsocialnetwork

  1. High-Throughput Screening as a Supplemental Tool for the Development of Advanced Emission Control Catalysts: Methodological Approaches and Data Processing

    Directory of Open Access Journals (Sweden)

    Andreas Sundermann

    2016-01-01

    Full Text Available A high-throughput (HT screening platform developed at hte with the application focus on automotive catalysis is described. hte HT units are configured for performing steady-state testing, as well as dynamic tests with fast feed switches, such as lean/rich excursions for the evaluation of NOx storage capacity and efficiency of lean NOx traps (LNT, ammonia storage capacity for selective catalytic reduction (SCR, evaluation of oxygen storage capacity (OSC, as well as lambda sweep tests for screening of three-way catalysts (TWC. Even though catalysts are screened on a rather small scale (~100 mg powder, experience showed that dosing rather complex gas mixtures in concentrations close to that found in real exhaust for the given application is mandatory to generate relevant data. The objective of this work is to give additional insight into HT technology. In the industrial research laboratory, HT screening has matured to become a reliable approach for rapid screening of both reaction parameter spaces, as well as material properties relevant for exhaust gas catalyst development. Due to the speed of optimized screening involving 48 parallel reactors, automated handling of primary data is an imported requirement. Software for data reduction, like estimation of light-off temperature, needs to be robust and handle results for diverse sample libraries in an unattended fashion. In combination with the statistical design of experiment and multivariate data analysis, HT testing has become a valuable enhancement to automotive catalyst development.

  2. The help of Advanced Satellite Interferometry in assessing the effect of human-induced surface deformation in naturally subsiding areas. Methodological approach and applications

    Science.gov (United States)

    Tamburini, Andrea; Giannico, Chiara; Del Conte, Sara; Teatini, Pietro

    2014-05-01

    Underground water extraction, natural gas storage either in depleted hydrocarbon reservoirs or in aquifers, and excavations for civil works (e.g. underground passageways, car parks, etc.) in flat areas are responsible for surface deformation that can damage pre-existing structures and modify drainage pathways. Deformation patterns associated to different underground show in many cases typical patterns. Their recognition can help in disentangling different processes when occurring in areas already affected by natural subsidence, such as coastal areas and inner sedimentary plains. Moreover, assessing the extent of human-induced deformation can help in identifying causes, modelling phenomena, predicting their evolution and adopting proper remedial measures. Advanced Satellite Interferometry provides a synoptic view of surface displacements over large areas and long time-spans and has become a standard in several Italian regions where underground fluid injection and withdrawal is going on. The integration of interferometric measurements with ground (leveling, GPS) and underground (borehole extensometers, piezometers, micro-seismic) monitoring networks can provide an exhaustive framework of the effect induced at surface level by underground human activities at local and regional scale. Documented case studies demonstrating the effectiveness of the above approach will be presented.

  3. THE AGILE METHODOLOGY

    Directory of Open Access Journals (Sweden)

    Charul Deewan

    2012-09-01

    Full Text Available The technologies are numerous and Software is the one whichis most widely used. Some companies have their owncustomized methodology for developing their software but themajority speaks about two kinds of methodologies: Traditionaland Agile methodologies. In this paper, we will discuss someof the aspects of what Agile methodology is, how it can beused to get the best result from a project, how do we get it towork in an organization.

  4. Geochemical evidence of multistage retrogressive failure during the 160,000ka Icod landslide from turbidite facies analysis: multidisciplinary investigative approaches using destructive and non-destructive methodologies

    Science.gov (United States)

    Hunt, James; Wynn, Russell; Masson, Doug; Croudace, Ian

    2010-05-01

    The study of modern deep-sea systems through targeted piston coring has enabled detailed investigations into the process mechanics of turbidity currents. In complex systems such as the Moroccan Turbidite System the derivation of provenance is of vital importance, since flows from different sources in this system have been found to behave differently. Early provenance studies in the Madeira Abyssal Plain found that bulk sand-fraction geochemical analysis through ICP-AES could enable successful attribution of provenance to specific turbidites alongside electron microprobe analysis (de Lange, Jarvis & Kuijpers, 1987; Pearce & Jarvis, 1992). These sources including the Moroccan siliclastic shelf, Tenerife, Las Palma, El Hierro and Madeira. ICP-AES, MC-ICP-MS and XRF have been utilised here, however these present destructive methodologies, using 0.1-5g of material >63µm. Deep-sea piston cores are also expensive to collect, and often there is not enough material to remove for analysis without compromising the core. Furthermore, routine sampling, preparation and analysis using the destructive methods stated above are undertaken at considerable cost and analytical time. The successful use of non-destructive instruments to yield quantitative geochemical has become paramount at the NOC. This presentation serves to show the successful application of the TM-1000 tabletop SEM EDS analyser, ITRAX micro-XRF analyser and the GEOTEK XYZ logger, in coincidence with traditional destructive methods. These instruments can only supply semi-quantitative data, unless correct calibration can be achieved, and will be shown here. The 160,000ka Icod landslide from Tenerife generated a 150km3 debris avalanche with a runout of 105km and a >180km3 turbidity, which will form the case study for application of these instruments. The vertically stacked subunit facies of the Icod turbidite has been attributed to generation from a multistage retrogressive failure (Wynn & Masson, 2003). Here there

  5. L'approache ethnographique comme Methodologie de recherche dans l'examen du processus de construction identitaire (The Ethnographic Approach as Research Methodology in the Investigation of the Process of Identity Construction).

    Science.gov (United States)

    Gerin-Lajoie, Diane

    2002-01-01

    Demonstrates how qualitative research, specifically ethnograhy, constitutes an effective means of investigating identity construction, particularly as identity is manifested through language practices. This approach illuminates the complexity of the interaction between language practices and identity. (Author/VWL)

  6. THE WEALTH, THE MORALITY AND THE HAPPINESS AS A BASIC CATEGORIES OF THE NEW ECONOMY FORMATION: THE THEORETICAL AND METHODOLOGICAL APPROACH

    Directory of Open Access Journals (Sweden)

    Rumyantseva E. E.

    2015-02-01

    Full Text Available In the article we have considered the new valuable reference points of the economy development of Russia characterized by such intrinsic categories as "wealth", "moral" and "happiness". On the subject of the conducted research, there is analyzed the moral position laid down in the Scriptures (in example the «Holy gospel», the works of A. Smith, K., Marx, J.C. Sismondi, J.B. Say, A. Marshall, J. Stiglitz. Such important contemporary Russian society problems are formulated, such as: the disclosure of the relationship of the national wealth with its spiritual and moral development as an property; the depreciation of the moral values in the unspiritual elite of the society; the purity, the clarity, the innocence origin of the wealth of the every citizen; the grounds for the origin of the inequality in the world and in Russia and scientific stratification; the misconceptions about the correlation of the spirituality and the wealth or the poverty, the expectations of the happiness from outside are identified, the author laws of the morality development in the economics are formulated. Another important issue is the access to the distribution of the natural resources of the country, the distribution between the different members of the society. The main conclusion of the article is that in the economics of the happiness should be set such rules, in accordance with which the individual could become rich through his labour in the process of the spiritual and moral growth. We have used the author's scientific approach of a criteria assessment of the economic development vectors on positive and negative, there are investigated the directions of the improvement of the modern Russian legislation

  7. Detection, characterization and quantification of inorganic engineered nanomaterials: A review of techniques and methodological approaches for the analysis of complex samples.

    Science.gov (United States)

    Laborda, Francisco; Bolea, Eduardo; Cepriá, Gemma; Gómez, María T; Jiménez, María S; Pérez-Arantegui, Josefina; Castillo, Juan R

    2016-01-21

    dealing with complex samples. Single- and multi-method approaches applied to solve the nanometrological challenges posed by a variety of stakeholders are also presented.

  8. Q methodology in health economics.

    Science.gov (United States)

    Baker, Rachel; Thompson, Carl; Mannion, Russell

    2006-01-01

    The recognition that health economists need to understand the meaning of data if they are to adequately understand research findings which challenge conventional economic theory has led to the growth of qualitative modes of enquiry in health economics. The use of qualitative methods of exploration and description alongside quantitative techniques gives rise to a number of epistemological, ontological and methodological challenges: difficulties in accounting for subjectivity in choices, the need for rigour and transparency in method, and problems of disciplinary acceptability to health economists. Q methodology is introduced as a means of overcoming some of these challenges. We argue that Q offers a means of exploring subjectivity, beliefs and values while retaining the transparency, rigour and mathematical underpinnings of quantitative techniques. The various stages of Q methodological enquiry are outlined alongside potential areas of application in health economics, before discussing the strengths and limitations of the approach. We conclude that Q methodology is a useful addition to economists' methodological armoury and one that merits further consideration and evaluation in the study of health services.

  9. The predisposition, infection, response and organ failure (Piro sepsis classification system: results of hospital mortality using a novel concept and methodological approach.

    Directory of Open Access Journals (Sweden)

    Cristina Granja

    Full Text Available INTRODUCTION: PIRO is a conceptual classification system in which a number of demographic, clinical, biological and laboratory variables are used to stratify patients with sepsis in categories with different outcomes, including mortality rates. OBJECTIVES: To identify variables to be included in each component of PIRO aiming to improve the hospital mortality prediction. METHODS: Patients were selected from the Portuguese ICU-admitted community-acquired sepsis study (SACiUCI. Variables concerning the R and O component included repeated measurements along the first five days in ICU stay. The trends of these variables were summarized as the initial value at day 1 (D1 and the slope of the tendency during the five days, using a linear mixed model. Logistic regression models were built to assess the best set of covariates that predicted hospital mortality. RESULTS: A total of 891 patients (age 60±17 years, 64% men, 38% hospital mortality were studied. Factors significantly associated with mortality for P component were gender, age, chronic liver failure, chronic renal failure and metastatic cancer; for I component were positive blood cultures, guideline concordant antibiotic therapy and health-care associated sepsis; for R component were C-reactive protein slope, D1 heart rate, heart rate slope, D1 neutrophils and neutrophils slope; for O component were D1 serum lactate, serum lactate slope, D1 SOFA and SOFA slope. The relative weight of each component of PIRO was calculated. The combination of these four results into a single-value predictor of hospital mortality presented an AUC-ROC 0.84 (IC(95%:0.81-0.87 and a test of goodness-of-fit (Hosmer and Lemeshow of p = 0.368. CONCLUSIONS: We identified specific variables associated with each of the four components of PIRO, including biomarkers and a dynamic view of the patient daily clinical course. This novel approach to PIRO concept and overall score can be a better predictor of mortality for

  10. Methodological Approaches for Estimating Gross Regional Product after Taking into Account Depletion of Natural Resources, Environmental Pollution and Human Capital Aspects

    Directory of Open Access Journals (Sweden)

    Boris Alengordovich Korobitsyn

    2015-09-01

    Full Text Available A key indicator of the System of National Accounts of Russia at a regional scale is Gross Regional Product characterizing the value of goods and services produced in all sectors of the economy in a country and intended for final consumption, capital formation and net exports (excluding imports. From a sustainability perspective, the most weakness of GRP is that it ignores depreciation of man-made assets, natural resource depletion, environmental pollution and degradation, and potential social costs such as poorer health due to exposure to occupational hazards. Several types of alternative approaches to measuring socio-economic progress are considering for six administrative units of the Ural Federal District for the period 2006–2014. Proposed alternatives to GRP as a measure of social progress are focused on natural resource depletion, environmental externalities and some human development aspects. The most promising is the use of corrected macroeconomic indicators similar to the “genuine savings” compiled by the World Bank. Genuine savings are defined in this paper as net savings (net gross savings minus consumption of fixed capital minus the consumption of natural non-renewable resources and the monetary evaluations of damages resulting from air pollution, water pollution and waste disposal. Two main groups of non renewable resources are considered: energy resources (uranium ore, oil and natural gas and mineral resources (iron ore, copper, and aluminum. In spite of various shortcomings, this indicator represents a considerable improvement over GRP information. For example, while GRP demonstrates steady growth between 2006 and 2014 for the main Russian oil- and gas-producing regions — Hanty-Mansi and Yamalo-Nenets Autonomous Okrugs, genuine savings for these regions decreased over all period. It means that their resource-based economy could not be considered as being on a sustainable path even in the framework of

  11. Photovoltaic module energy rating methodology development

    Energy Technology Data Exchange (ETDEWEB)

    Kroposki, B.; Myers, D.; Emery, K.; Mrig, L. [National Renewable Energy Lab., Golden, CO (United States); Whitaker, C.; Newmiller, J. [Endecon Engineering, San Ramon, CA (United States)

    1996-05-01

    A consensus-based methodology to calculate the energy output of a PV module will be described in this paper. The methodology develops a simple measure of PV module performance that provides for a realistic estimate of how a module will perform in specific applications. The approach makes use of the weather data profiles that describe conditions throughout the United States and emphasizes performance differences between various module types. An industry-representative Technical Review Committee has been assembled to provide feedback and guidance on the strawman and final approach used in developing the methodology.

  12. Qualitative Research: Methods and Methodology

    OpenAIRE

    Gabb, Jacqui

    2016-01-01

    This entry provides an overview of qualitative LGBTQ research. It begins by mapping out the qualities and character of studies that use this approach with particular attention to psycho-social research. It then highlights how reflexivity, the iterative process of self-identity making, has informed qualitative research, influencing both understandings of sexualities and also the underlying methodologies and research methods used. Finally, it considers how “the everyday” and a practices approac...

  13. In silico and in vitro physicochemical screening of Rigidoporus sp. crude laccase-assisted decolorization of synthetic dyes--approaches for a cost-effective enzyme-based remediation methodology.

    Science.gov (United States)

    Sridhar, S; Chinnathambi, V; Arumugam, P; Suresh, P K

    2013-02-01

    The objective of this paper is to compare in silico data with wet lab physicochemical properties of crude laccase enzyme isolated from Rigidoporus sp. using wheat bran as solid substrate support towards dye decolorization. Molecular docking analysis of selected nine textile and non-textile dyes were performed using laccase from Rigidoporus lignosus as reference protein. Enzyme-based remediation methodology using crude enzyme enriched from solid state fermentation was applied to screen the effect of four influencing variables such as pH, temperature, dye concentration, and incubation time toward dye decolorization. The extracellular crude enzyme decolorized 69.8 % Acid Blue 113, 45.07 % Reactive Blue 19, 36.61 % Reactive Orange 122, 30.55 % Acid Red 88, 24.59 % Direct Blue 14, 18.48 % Reactive Black B, 16.49 % Reactive Blue RGB, and 11.66 % Acid Blue 9 at 100 mg/l dye concentration at their optimal pH at room temperature under static and dark conditions after 1 h of incubation without addition of any externally added mediators. Our wet lab studies approach, barring other factors, validate in silico for screening and ranking textile dyes based on their proximity to the T1 site. We are reporting for the first time a combinatorial approach involving in silico methods and wet lab-based crude laccase-mediated dye decolorization without any external mediators.

  14. Methodological approach for the assessment of ultrasound reproducibility of cardiac structure and function: a proposal of the study group of Echocardiography of the Italian Society of Cardiology (Ultra Cardia SIC) Part I

    Science.gov (United States)

    2011-01-01

    When applying echo-Doppler imaging for either clinical or research purposes it is very important to select the most adequate modality/technology and choose the most reliable and reproducible measurements. Quality control is a mainstay to reduce variability among institutions and operators and must be obtained by using appropriate procedures for data acquisition, storage and interpretation of echo-Doppler data. This goal can be achieved by employing an echo core laboratory (ECL), with the responsibility for standardizing image acquisition processes (performed at the peripheral echo-labs) and analysis (by monitoring and optimizing the internal intra- and inter-reader variability of measurements). Accordingly, the Working Group of Echocardiography of the Italian Society of Cardiology decided to design standardized procedures for imaging acquisition in peripheral laboratories and reading procedures and to propose a methodological approach to assess the reproducibility of echo-Doppler parameters of cardiac structure and function by using both standard and advanced technologies. A number of cardiologists experienced in cardiac ultrasound was involved to set up an ECL available for future studies involving complex imaging or including echo-Doppler measures as primary or secondary efficacy or safety end-points. The present manuscript describes the methodology of the procedures (imaging acquisition and measurement reading) and provides the documentation of the work done so far to test the reproducibility of the different echo-Doppler modalities (standard and advanced). These procedures can be suggested for utilization also in non referall echocardiographic laboratories as an "inside" quality check, with the aim at optimizing clinical consistency of echo-Doppler data. PMID:21943283

  15. Vygotski e Sartre: aproximando concepções metodológicas na construção do saber psicológico Vygotski and Sartre: approaching methodological conceptions in the construction of psychological knowledge

    Directory of Open Access Journals (Sweden)

    Kátia Maheirie

    2007-04-01

    Full Text Available Para apontar contribuições metodológicas de Sartre e Vygotski à Psicologia, este artigo recupera as obras: "O significado histórico da crise da psicologia. Uma investigação metodológica" (Vygotski, 1996 e "Questão de método" (Sartre, 1960/1987. Em seu texto, Vygotski identifica uma crise na Psicologia daquele tempo, indicando sua superação por uma abordagem metodológica calcada nas reflexões de Marx. Também Sartre retorna aos escritos marxianos, visando o sujeito como singularidade irredutível que se constitui nas relações sociais. Finalmente, Sartre e Vygotski defendem posturas metodológicas que abarquem, simultaneamente, o sujeito ímpar e a totalização histórica inacabada em que se faz. Cada autor, a sua maneira, advoga a especificidade que caracteriza o humano, concebendo a subjetividade na relação com a objetividade, num movimento dialético incessante. Entendendo o sujeito como produto e produtor da cultura, os autores podem colaborar para uma psicologia comprometida com seu contexto político, porque orientada por uma perspectiva de transformação social.This article aims to point out Vygotsky's and Sartre's methodological contributions to psychology, using the following literature: "O significado histórico da crise da psicologia. Uma investigação metodológica" (Vygotsky, 1996 and "Questão de Método" (Sartre, 1987. Vygotsky identifies a psychological crisis, indicating that to overcome it depends on a methodological approach based on Marx's thoughts. Sartre also returns to Marx's writings, to define the subject as an irreducible singularity which is constituted on social relations. Finally, Sartre and Vygotsky share a methodological position which comprehends, simultaneously, the singularity of human beings and its unfinished historical totalizing process. Each author, in his own way, assumes specificities that characterize the human being, conceiving subjectivity in an incessant and dialectic relation with

  16. Reliability Centered Maintenance - Methodologies

    Science.gov (United States)

    Kammerer, Catherine C.

    2009-01-01

    Journal article about Reliability Centered Maintenance (RCM) methodologies used by United Space Alliance, LLC (USA) in support of the Space Shuttle Program at Kennedy Space Center. The USA Reliability Centered Maintenance program differs from traditional RCM programs because various methodologies are utilized to take advantage of their respective strengths for each application. Based on operational experience, USA has customized the traditional RCM methodology into a streamlined lean logic path and has implemented the use of statistical tools to drive the process. USA RCM has integrated many of the L6S tools into both RCM methodologies. The tools utilized in the Measure, Analyze, and Improve phases of a Lean Six Sigma project lend themselves to application in the RCM process. All USA RCM methodologies meet the requirements defined in SAE JA 1011, Evaluation Criteria for Reliability-Centered Maintenance (RCM) Processes. The proposed article explores these methodologies.

  17. Cancer cytogenetics: methodology revisited.

    Science.gov (United States)

    Wan, Thomas S K

    2014-11-01

    The Philadelphia chromosome was the first genetic abnormality discovered in cancer (in 1960), and it was found to be consistently associated with CML. The description of the Philadelphia chromosome ushered in a new era in the field of cancer cytogenetics. Accumulating genetic data have been shown to be intimately associated with the diagnosis and prognosis of neoplasms; thus, karyotyping is now considered a mandatory investigation for all newly diagnosed leukemias. The development of FISH in the 1980s overcame many of the drawbacks of assessing the genetic alterations in cancer cells by karyotyping. Karyotyping of cancer cells remains the gold standard since it provides a global analysis of the abnormalities in the entire genome of a single cell. However, subsequent methodological advances in molecular cytogenetics based on the principle of FISH that were initiated in the early 1990s have greatly enhanced the efficiency and accuracy of karyotype analysis by marrying conventional cytogenetics with molecular technologies. In this review, the development, current utilization, and technical pitfalls of both the conventional and molecular cytogenetics approaches used for cancer diagnosis over the past five decades will be discussed.

  18. Multiobjective Optimization Methodology A Jumping Gene Approach

    CERN Document Server

    Tang, KS

    2012-01-01

    Complex design problems are often governed by a number of performance merits. These markers gauge how good the design is going to be, but can conflict with the performance requirements that must be met. The challenge is reconciling these two requirements. This book introduces a newly developed jumping gene algorithm, designed to address the multi-functional objectives problem and supplies a viably adequate solution in speed. The text presents various multi-objective optimization techniques and provides the technical know-how for obtaining trade-off solutions between solution spread and converg

  19. Photochemical processes for atrazine degradation: methodological approach.

    Science.gov (United States)

    Héquet, V; Gonzalez, C; Le Cloirec, P

    2001-12-01

    Numerous studies have been carried out on s-triazines, and more specifically on atrazine, with the long-term objective of resolving the problems caused by these herbicides: removing them from drinking water. However, applications have remained too limited. So far, processes based on photochemical degradation have been little implemented. We, therefore, investigated the development of photochemical processes, emphasizing their capacity to degrade triazine by photolytic and photocatalytic mode. The study sought to assess the performance of these ssstems. Experiments ts showed that according to a medium pressure mercury source (UV-Vis irradiation), the photolytic degradation of atrazine was very efficient, with a best atrazine degradation half-life shorter that 5 min. The main degradation pathway was deshalogenation. The photocatalytic degradation of atrazine under irradiation over 290 nm in the presence of titanium dioxide was shown to be efficient too, with a half-life of about 20 min. In this case an experimental design was conducted so as to assess the influence of various parameters: pH, water medium, and amount of catalyst. There has been observational evidence for the efficiency of the processes investigated here and for potential technological developments as regards drinking water treatment.

  20. Bathymetry of Reykjanes Ridge: A methodological approach

    OpenAIRE

    Banul, Karolina, 1987-

    2014-01-01

    The sea floor is one of the Earths parts that still are mostly unexplored. Recent multibeam technology has now opened up new opportunities to increase our knowledge in this hitherto hidden part of the world. In this study part of the Reykjanes Ridge was analysed in order to create a high resolution and comprehensive topographic map of this northern part of the Mid-Atlantic Ocean Ridge. The general aims of the study were to i) develop seamless method from Caris, a raw analytical program for mu...