WorldWideScience

Sample records for bezoars

  1. [Gastrointestinal bezoars].

    Science.gov (United States)

    Espinoza González, Ricardo

    2016-08-01

    Gastrointestinal bezoars are a concretion of indigested material that can be found in the gastrointestinal tract of humans and some animals. This material forms an intraluminal mass, more commonly located in the stomach. During a large period of history animal bezoars were considered antidotes to poisons and diseases. We report a historical overview since bezoars stones were thought to have medicinal properties. This magic conception was introduced in South America by Spanish conquerors. In Chile, bezoars are commonly found in a camelid named guanaco (Lama guanicoe). People at Central Chile and the Patagonia believed that bezoar stones had magical properties and they were traded at very high prices. In Santiago, during the eighteenth century the Jesuit apothecary sold preparations of bezoar stones. The human bezoars may be formed by non-digestible material like cellulose (phytobezoar), hair (trichobezoar), conglomerations of medications or his vehicles (pharmacobezoar or medication bezoar), milk and mucus component (lactobezoar) or other varieties of substances. This condition may be asymptomatic or can produce abdominal pain, ulceration, gastrointestinal bleeding, gastric outlet obstruction, perforation and mechanical intestinal obstruction. We report their classification, diagnostic modalities and treatment.

  2. [Bezoars in history--not only a perfect antidote].

    Science.gov (United States)

    Ryś, Anna; Siek, Bartłomiej; Sein Anand, Jacek

    2012-01-01

    Bezoar is a concretion found in gastrointestinal tract. The word "bezoar" is derived from the Arabic 'padzahr', and means antidote. Animal bezoars were widely used in medicine until the 18th century. Article presents European medieval and modern tradition about bezoar as an antidote. Ancient literary sources are compared with the medieval and modern medical and magical texts.

  3. Relapsing massive metal bezoar: a case report

    Directory of Open Access Journals (Sweden)

    Prieto-Aldape Manuel

    2009-02-01

    Full Text Available Abstract Introduction Bezoars are uncommon findings in the gastrointestinal tract and are composed of a wide variety of materials. We report a case of a relapsing metal bezoar in a man with schizophrenia. Case presentation A 34-year-old man presented with a history of sub-acute onset of mild diffuse abdominal pain and abdominal distention. Physical examination revealed dullness to percussion in the upper and lower left quadrants. Past medical history was remarkable for epilepsy, schizophrenia and previous abdominal surgery for intestinal occlusion. Plain radiographs revealed objects of metal density contained within a dilated stomach. Celiotomy was performed revealing more than 350 metal objects inside the stomach. The patient was discharged and referred to a psychiatric facility. Conclusion Intestinal occlusion in patients with psychiatric disorders can result from rare causes such as bezoars. This report alerts surgeons to rule out bezoars in the differential diagnosis of intestinal occlusion in people with mental health problems.

  4. A Literary Study on Bezoar Bovis

    Directory of Open Access Journals (Sweden)

    Seong Kyu Park

    2005-12-01

    Full Text Available Objectives : Literary investigation of existing data was conducted to verify effects of Bezoar Bovis and its herbal acupuncture, and determine quality management through component analysis. Results : Following results were obtained through literary investigation. 1. Bezoar Bovis is dried cystic stone from a cattle. Its characteristics are cool, no toxicity, and bitter taste. Known actions are: quells heat and detoxifies Fire Poison, extinguishes internal movement of Liver Wind and stops convulsion, vaporizes phlegm, and opens orifice. It is mainly used for treating tremor, stroke, delirium, sore throat, oral furuncle, boil, and others. 2. Bezoar Bovis is effective for eliminating liver toxicity, protecting against brain damage, and has anti-microbial activities. 3. Bezoar Bovis is mixed with bear gall bladder and deer musk to be used as herbal acupuncture, and this mixture is effective is invigorating liver functions as well as treating arthritis, headache, and etc. 4. Principal components of Bezoar Bovis are bilirubin-type pigments and cholic acids. The amount of bilirubin can be used as a standard to determine the quality of Bezoar Bovis.

  5. Review of the diagnosis and management of gastrointestinal bezoars.

    Science.gov (United States)

    Iwamuro, Masaya; Okada, Hiroyuki; Matsueda, Kazuhiro; Inaba, Tomoki; Kusumoto, Chiaki; Imagawa, Atsushi; Yamamoto, Kazuhide

    2015-04-16

    The formation of a bezoar is a relatively infrequent disorder that affects the gastrointestinal system. Bezoars are mainly classified into four types depending on the material constituting the indigestible mass of the bezoar: phytobezoars, trichobezoars, pharmacobezoars, and lactobezoars. Gastric bezoars often cause ulcerative lesions in the stomach and subsequent bleeding, whereas small intestinal bezoars present with small bowel obstruction and ileus. A number of articles have emphasized the usefulness of Coca-Cola(®) administration for the dissolution of phytobezoars. However, persimmon phytobezoars may be resistant to such dissolution treatment because of their harder consistency compared to other types of phytobezoars. Better understanding of the etiology and epidemiology of each type of bezoar will facilitate prompt diagnosis and management. Here we provide an overview of the prevalence, classification, predisposing factors, and manifestations of bezoars. Diagnosis and management strategies are also discussed, reviewing mainly our own case series. Recent progress in basic research regarding persimmon phytobezoars is also briefly reviewed.

  6. Therapeutic approach to Candida bezoar in children

    NARCIS (Netherlands)

    De Wall, L. L.; Van Den Heijkant, M. M C; Bökenkamp, A.; Kuijper, C. F.; Van Der Horst, H. J R; De Jong, T. P V M

    2015-01-01

    Introduction Candida bezoar (CB) is a rare finding in neonates and infants with candiduria, presenting as necrotic debris with proliferating mycelia in the collecting system of the kidney. If initial antifungal medical treatment does not result in clearance of candiduria and disappearance of CB on u

  7. A Case of Safe Endoscopic Removal of a Gastric Bezoar

    OpenAIRE

    Tanioka, Yukari; Yanai, Hideo; Nakamura, Youhei; Okamoto, Takeshi; Saiki, Yasuhiko; Yoshida, Tomoharu; Okita, Kiwamu; Murashige, Takeyosi

    2004-01-01

    Gastric bezoars are relativery uncommon and have a reported incidence of 0.4%. Because of complications such as gastric ulcers, intestinal obstruction, and perforation, gastric bezoars need to be removed in some cases. We experienced a patient with a 5 x 6cm gastric bezoar. We could easily and safely break and remove it using standard endoscopic techniques. It was throught to a persimmon bezoar as the infrared (IR) spectrum was similar to that of tannic acid, which is a main component of the ...

  8. The bezoar stone: a princely antidote, the Távora Sequeira Pinto Collection-Oporto.

    Science.gov (United States)

    Do Sameiro Barroso, Maria

    2014-01-01

    Bezoar stones, once used as universal antidotes and panaceas, but currently regarded as costly and useless medicines of the past, are a major milestone in the history of toxicology. Arabic physicians had been using bezoars in medicine from the 8th century onwards. In the 16th century, the Portuguese controlled bezoar trade from India, and the Portuguese doctors Garcia de Orta, Amatus Lusitanus, and Cristobal Acosta introduced the medicinal use of Oriental bezoars to European medical literature. Some criticism aside, leading European doctors prescribed bezoars mainly as powerful antidotes. Five bezoars that now adorn the Távora Sequeira Pinto Collection in Oporto testify to the allure and glory of bezoars at the height of their golden age, when they equalled the splendour of gems and noble minerals that dominated the Eastern and Western lithotherapy.The end of the 18th century marked the end of ancient panaceas. This article focuses on the therapeutic and apotropaic use of bezoars.

  9. Duodenal obstruction following acute pancreatitis caused by a large duodenal diverticular bezoar

    Institute of Scientific and Technical Information of China (English)

    Ji Hun Kim; Jae Hyuck Chang; Sung Min Nam; Mi Jeong Lee; Il Ho Maeng; Jin Young Park; Yun Sun Im

    2012-01-01

    Bezoars are concretions of indigestible materials in the gastrointestinal tract.It generally develops in patients with previous gastric surgery or patients with delayed gastric emptying.Cases of periampullary duodenal divericular bezoar are rare.Clinical manifestations by a bezoar vary from no symptom to acute abdominal syndrome depending on the location of the bezoar.Biliary obstruction or acute pancreatitis caused by a bezoar has been rarely reported.Small bowel obstruction by a bezoar is also rare,but it is a complication that requires surgery.This is a case of acute pancreatitis and subsequent duodenal obstruction caused by a large duodenal bezoar migrating from a periampullary diverticulum to the duodenal lumen,which mimicked pancreatic abscess or microperforation on abdominal computerized tomography.The patient underwent surgical removal of the bezoar and recovered completely.

  10. Acute small bowel obstruction due to chicken bone bezoar

    Directory of Open Access Journals (Sweden)

    Vetpillai P

    2012-12-01

    Full Text Available Preadeepan Vetpillai,1 Ayo Oshowo21CT2 Surgery in General, Charing Cross Hospital, 2Colorectal and Laparoscopic Surgery, Whittington Hospital, London, UKAbstract: Acute intestinal obstruction due to foreign bodies, or bezoar, is a rare occurrence in an adult with a normal intestinal tract. We report an unusual case of a 43-year-old black man with no previous abdominal surgery and no significant medical history who presented with an acute episode of small bowel obstruction due to an impacted undigested chicken bone.Keywords: small bowel obstruction, chicken bone, bezoar

  11. Bezoar in a Pediatric Oncology Patient Treated with Coca-Cola.

    Science.gov (United States)

    Naramore, Sara; Virojanapa, Amy; Bell, Moshe; Jhaveri, Punit N

    2015-01-01

    A bezoar is a mass of indigestible material. Bezoars can present with a gradual onset of non-specific gastrointestinal symptoms including abdominal pain, nausea and vomiting. However, bezoars can result in more serious conditions such as intestinal bleeding or obstruction. Without quick recognition, particularly in susceptible individuals, the diagnosis and treatment can be delayed. Currently resolution is achieved with enzymatic dissolution, endoscopic fragmentation or surgery. We describe, to our knowledge, the first pediatric patient with lymphoma to have had a bezoar treated with Coca-Cola.

  12. Bezoar in a Pediatric Oncology Patient Treated with Coca-Cola

    Directory of Open Access Journals (Sweden)

    Sara Naramore

    2015-07-01

    Full Text Available A bezoar is a mass of indigestible material. Bezoars can present with a gradual onset of non-specific gastrointestinal symptoms including abdominal pain, nausea and vomiting. However, bezoars can result in more serious conditions such as intestinal bleeding or obstruction. Without quick recognition, particularly in susceptible individuals, the diagnosis and treatment can be delayed. Currently resolution is achieved with enzymatic dissolution, endoscopic fragmentation or surgery. We describe, to our knowledge, the first pediatric patient with lymphoma to have had a bezoar treated with Coca-Cola.

  13. Perforated duodenal diverticulum caused by Bezoar: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Jung; Moon, Sung Kyoung; Park, Seong Jin; Lim, Joo Won; Lee, Dong Ho; Ko, Young Tae [Dept. of Radiology, College of Medicine, Kyung Hee University, Seoul (Korea, Republic of)

    2013-11-15

    Duodenal diverticulum is common, but its perforation is a rare complication. Duodenal diverticulum perforation requires prompt treatments because of its high mortality rate. However, an accurate diagnosis is difficult to make due to nonspecific symptoms and signs. It can be misdiagnosed as pancreatitis, cholecystitis, or peptic ulcer. Herein, we report a case of perforated duodenal diverticulum caused by bezoar in a 33-year-old woman whom was diagnosed by abdomen computed tomography and ultrasonography.

  14. Case report: Colonic bezoar due to box myrtle seeds: A very rare occurrence

    Directory of Open Access Journals (Sweden)

    Narvir Singh Chauhan

    2011-01-01

    Full Text Available Large bowel seed bezoars are rare and are mostly due to seeds of sunflower, prickly pear cactus, sesame and cucumber. We present a rare case of sigmoid colon seed bezoar due to Box Myrtle seeds because of an underlying benign stricture.

  15. Gastric bezoar after Roux-en-Y gastric bypass for morbid obesity: A case report

    Science.gov (United States)

    Ertugrul, Ismail; Tardum Tardu, Ali; Tolan, Kerem; Kayaalp, Cuneyt; Karagul, Servet; Kirmizi, Serdar

    2016-01-01

    Introduction We aimed to present a patient with gastric pouch bezoar after having a bariatric surgery. Presentation of case Sixty-three years old morbid obese female had a laparoscopic Roux-en-Y gastric bypass surgery 14 months ago. She has lost 88% of her excess body mass index; but started to suffer from nausea, abdominal distention and vomiting lately, especially for the last two months. The initial evaluation by endoscopy, computed tomography (CT) and an upper gastrointestinal contrast series overlooked the pathology in the gastric pouch and did not display any abnormality. However, a second endoscopy revealed a 5 cm in diameter phytobezoar in the gastric pouch which was later endoscopically removed. After the bezoar removal, her complaints relieved completely. Discussion The gastric bezoars may be confused with the other pathologies because of the dyspeptic complaints of these patients. The patients that had a bariatric surgery; are more prone to bezoar formation due to their potential eating disorders and because of the gastro-enterostomy made to a small gastric pouch after the Roux-en-Y gastric bypass surgery. Conclusion Possibility of a bezoar formation should be kept in mind in Roux-en-Y gastric bypass patients who has nausea and vomiting complaints. Removal of the bezoar provides a dramatic improvement in the complaints of these patients. PMID:27107501

  16. Bezoar de madeira em trato gastrointestinal: relato de caso e revisão da literatura Wood bezoar in the gastrointestinal tract: case report and literature review

    OpenAIRE

    Jair Gimenez Marra; Ary Leite de Campos Sobrinho; Kreisky de Los Santos Rebaza; Josenalda Félix Flores Aratani; Eloísa Almeida Curvo

    2007-01-01

    INTRODUÇÃO: Bezoares são concreções de material animal, vegetal ou mineral retidas do tubo digestivo, sendo mais comuns fitobezoares e tricobezoares. Eles são causadores de várias doenças digestivas, incluindo obstruções, intussuscepções, sangramentos, perfurações, além de enteropatias, pancreatites, apendicites, icterícia obstrutiva e outras. OBJETIVO: Fazer revisão de literatura e apresentar um caso de paciente psiquiátrica com volumoso bezoar de madeira. RELATO DO CASO: Mulher de 20 anos p...

  17. Synergistic effect of multiple predisposing risk factors on the development of bezoars

    Institute of Scientific and Technical Information of China (English)

    Metin Kement; Nuraydin Ozlem; Elif Colak; Sadik Kesmer; Cem Gezen; Selahattin Vural

    2012-01-01

    AIM:To describe the clinical characteristics of patients with gastric or intestinal bezoars recently treated in our hospital.METHODS:In this study,a retrospective chart review of consecutive patients with gastrointestinal bezoars,who were treated at the Samsun Education and Research Hospital between January 2006 and March 2011,was conducted.Data on demographic characteristics,clinical presentation,history of risk factors,diagnostic procedures,localization of bezoars,treatment interventions,and postoperative morbidity and mortality rates were collected and evaluated.RESULTS:Forty-two patients [26 (61.9%) males and 16 (31.1%) females] with a mean ± SD (range) age of 55.8 ± 10.5 (37-74) years were enrolled in this study,.Thirty-six patients (85.7%) had one or more predisposing risk factors for gastrointestinal bezoars.The most common predisposing risk factor was a history of previous gastric surgery which was identified in 18 patients (42.8%).Twenty three patients (54.8%) had multiple predisposing risk factors.Phytobezoars were identified in all patients except one who had a trichobezoar in the stomach.Non-operative endoscopic fragmentation was performed either initially or after unsuccessful medical treatment in 14 patients with gastric bezoars and was completely successful in 10 patients (71.5%).Surgery was the most frequent treatment method in our study,which was required in 28 patients (66.7%).Intestinal obstruction secondary to bezoars was the most common complication (n =18,42.8%) in our study.CONCLUSION:The presence of multiple predisposing factors may create a synergistic effect in the development of bezoars.

  18. An unusual cause of small bowel obstruction in children: lentil soup bezoar.

    Science.gov (United States)

    Plataras, Christos; Sardianos, Nektarios; Vlatakis, Stephanos; Nikas, Konstantinos

    2014-01-01

    Bezoars are an unusual cause of acute intestinal obstruction in children. Most cases are trichobezoars in adolescent girls who swallow their hair. Lactobezoars are another unusual but occasionally reported cause of intestinal obstruction in neonates. Phytobezoars and food bolus bezoars are the least common types of intestinal obstruction that have been reported in children. Of the few paediatric cases that have been described, the majority involve persimmons. Moreover, all of these cases involve the ingestion of raw fibres or fruit that have not been cooked. We report a case of a girl who presented with acute ileal obstruction because of lentil soup bezoar. Given the wide use of this otherwise nutritional foodstuff, we highlight the danger from its inappropriate preparation to the health of children. This is the first reported case of intestinal obstruction caused by lentils in children and we hope to raise concern among paediatricians regarding this matter.

  19. Bezoar de madeira em trato gastrointestinal: relato de caso e revisão da literatura Wood bezoar in the gastrointestinal tract: case report and literature review

    Directory of Open Access Journals (Sweden)

    Jair Gimenez Marra

    2007-12-01

    Full Text Available INTRODUÇÃO: Bezoares são concreções de material animal, vegetal ou mineral retidas do tubo digestivo, sendo mais comuns fitobezoares e tricobezoares. Eles são causadores de várias doenças digestivas, incluindo obstruções, intussuscepções, sangramentos, perfurações, além de enteropatias, pancreatites, apendicites, icterícia obstrutiva e outras. OBJETIVO: Fazer revisão de literatura e apresentar um caso de paciente psiquiátrica com volumoso bezoar de madeira. RELATO DO CASO: Mulher de 20 anos portadora de distúrbio neuropsiquiátrico tem história de ingestão de palitos de fósforos e lápis de cor durante quatro anos. Foi admitida com queixa de plenitude, dor abdominal e vômitos. Ao exame apresentava-se hipocorada, emagrecida, abdômen levemente distendido e doloroso. Estudo radiológico revelou numerosa quantidade de corpo estranho impactado na região gástrica atingindo porção proximal do intestino delgado. Realizado tratamento com óleo mineral e soro fisiológico através de gavagem, sendo eliminado grande número de fitobezoares nas fezes. CONCLUSÃO: A associação da patologia bezoar com distúrbios psiquiátricos é relevante, podendo apresentar recorrências. Estes pacientes sempre que possível devem ser tratados de modo conservador, sendo a endoscopia o método de escolha, apesar de estar limitada à natureza e a quantidade dos bezoares. A remoção cirúrgica tem na gastrotomia anterior longitudinal e a ordenha cautelosa o procedimento de escolha.BACKGROUND: Bezoars consist of animal, vegetable or mineral fiber concretions found in the digestive tract, considered to be phytobezoars and trichobezoars the most common forms of presentation. Bezoars cause a number of digestive pathologies including obstructions, intussusceptions, bleeding, perforations as well as enteropathies, pancreatitis, appendicitis, obstructive jaundice and others. Aim - Literature review and case report of a psychiatric patient presenting a

  20. Bezoar-related stercoral perforation in an 11-year old child: Has anyone seen my other sock?

    Directory of Open Access Journals (Sweden)

    John D. Rutkoski

    2015-05-01

    Full Text Available Bezoars are accretions of indigestible material that develop within the gastrointestinal tract and occur with relative infrequency. Rarer yet, stercoral perforations of the colon (SPC result from pressure-induced ischemia and are nearly universally associated with chronic constipation. We report only the second recorded case of a bezoar-related stercoral perforation of the colon, the first to result from ingestion of cloth, and the first in a pediatric patient.

  1. Plastic bezoar in the terminal ileum: a case report and imaging findings; Plastibezoar no ileo terminal: relato de caso e aspectos de imagem

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Gabriel Antonio de; Abikair Filho, Jorge [Hospital Infantil Nossa Senhora da Gloria, Vitoria, ES (Brazil); Werlang, Henrique Zambenedetti [MedImagem, Sao Paulo, SP (Brazil)]. E-mail: hzwerlang@gmail.com; Bergoli, Pedro Martins [SIDI - Servico de Investigacao Diagnostica, RS (Brazil)

    2006-04-15

    A 2 year old child presented with persistent abdominal pain and was referred to imaging studies. The abdominal ultrasound showed a hyper echogenic mass in the abdomen. Computed tomography scan showed a mass with very unusual density in the distal ileum. The patient was submitted to laparotomy and a large plastic bezoar was removed. In the medical literature, stomach bezoar, especially trichobezoar is a well known and described finding. No other case of plastic bezoar has been reported in similar imaging studies in the literature reviewed.(author)

  2. A giant gastric bezoar in billroth II stomach: a case report on successful endoscopic removal via repeated fragmentation and dissolution technique negating the need for surgical intervention

    Directory of Open Access Journals (Sweden)

    Jin Yu Chieng

    2016-08-01

    Full Text Available A 76-year-old gentleman presented with anemia. He had a history of perforated duodenal ulcer six years ago, with Billroth II repair performed. A large gastric bezoar (8X6cm2 with a clean base ulcer at the anastomotic junction was found during the initial Oesophago-gastro-duodenoscopy (OGDS. Rapid urease test was negative. He presented with melena during the subsequent follow up (OGDS showed a Forrest Ib prepylori ulcer. We have successful removed the gastric bezoar with dissolution therapy initially (injection of coke-cola into the bezoar, followed by drinking 325ml coca-cola twice daily, followed by four attempts of OGDS with endoscopic fragmentation. Histopathology reported as degenerated vegetable matter, acellular debris mixed with scattered fungal and bacterial colonies, which was compatible with bezoar. Follow up OGDS showed complete clearance of the bezoar. Coca-cola ingestion should be considered as initial treatment as it is non-invasive, and it enables further successful endoscopic fragmentation.

  3. Successful treatment with a combination of endoscopic injection and irrigation with coca cola for gastric bezoar-induced gastric outlet obstruction.

    Science.gov (United States)

    Lin, Chen-Sheng; Tung, Chun-Fang; Peng, Yen-Chun; Chow, Wei-Keung; Chang, Chi-Sen; Hu, Wei-Hsiung

    2008-01-01

    We report a case of gastric bezoar-induced gastric outlet obstruction that was successfully treated with a combination of endoscopic injection and irrigation with Coca Cola. A 73-year-old diabetic woman had a history of perforated peptic ulcer and had received pyloroplasty more than 20 years previously. She had been ingesting Pho Pu Zi (Cordia dichotoma Forst. f.) as an appetizer for 1 month. She presented with epigastric pain, nausea, and vomiting. Upper gastrointestinal endoscopy, performed at a local hospital, showed 2 gastric bezoars in the stomach, and 1 of them impacted at the pylorus. She was referred to our emergency department for removal of the gastric bezoars that were suspected to be causing gastric outlet obstruction. All attempts at endoscopic removal using a polypectomy snare, biopsy forceps and Dormia basket failed. We then injected Coca Cola directly into the bezoar mass, followed by irrigation with Coca Cola. Follow-up endoscopy was performed the next day, which revealed that the gastric bezoars had dissolved spontaneously.

  4. Gastric Outlet Obstruction--An Unexpected Complication during Coca-Cola Therapy for a Gastric Bezoar: A Case Report and Literature Review.

    Science.gov (United States)

    Lu, Lei; Zhang, Xiao-Feng

    2016-01-01

    Gastric bezoars are concretions of undigested material, and Coca-Cola therapy is an easy, efficacious and safe approach for bezoar treatment. Gastric outlet obstruction due to a migratory gastric bezoar during Coca-Cola therapy is an uncommon presentation and, to the best of our knowledge, no cases have been previously reported. We herein describe one such case with no known predisposing factors that recovered via the endoscopic technique. A thorough literature search was performed, which yielded eight relevant patients from seven publications, all of who developed gastrointestinal obstruction during dissolution treatment and recovered uneventfully after surgical intervention. In conclusion, this potential complication should be kept in mind in the event that alternative treatment is necessary.

  5. Foam bezoar: resection of perforated terminal ileum in a 17-year-old with sickle β+ thalassemia and pica.

    Science.gov (United States)

    Altepeter, Tara; Annes, John; Meller, Janet

    2011-07-01

    Children and adolescents with sickle cell disease demonstrate an increased incidence of pica. Pica involving polyurethane foam has been previously reported, but effective management of such cases remains unclear. We present the case of a 17-year-old African American adolescent girl with sickle β+ thalassemia who presented with a long history of foam rubber pica resulting in intestinal obstruction. Conservative management was unsuccessful, and the patient ultimately required operative intervention. We advocate for a low threshold for early operation in cases of foam rubber bezoar.

  6. 胃石症及其并发溃疡的内镜特点与幽门螺杆菌的关系%The Endoscopic Features of Gastric Bezoars and Their Complicating Ulcer and Relationship with Helicobacter Pylori

    Institute of Scientific and Technical Information of China (English)

    张亚辉; 张丽艳; 欧阳义; 邓丽君

    2014-01-01

    Objective:To summarize the endoscopic features of gastric bezoars and their complicating ulcer and to analyze its formation and the relationship between helicobacter pylori(H.pylori).Method:The clinical data of 62 patients who were diagnosed to have gastric bezoars by gastroscopy from June 2006 to May 2014 were selected.The endoscopic features of gastric bezoars and their complicating ulcer were analysed and H.pylori was detected by 14C-urea breath test.The 62 patients who had gastric bezoars were divided into two groups by whether the number of gastric bezoars was more than 2, whether the size of gastric bezoars was greater than 5 cm and whether gastric bezoars had ulcer complication.The patients infected by H.pylori were registered and the occurrence of H.pylori infection were compared in each group.Result:In 62 patients with gastric bezoars,the number of patients which their gastric bezoars located in fundus of stomach were 33 cases (53.23%),47 cases(75.81%)were the single gastric bezoars,and the maximum diameter of gastric bezoars varied from 2.5 to 11.0 cm;whether H.pylori infection was positive,most gastric bezoars were usually single and the size of gastric bezoars were usually less than 5 cm.The infection rate of H.pylori was 56.45%(35/62)in 62 patients with gastric bezoars. The percentage rate of multiple gastric bezoars(34.29%)in H.pylori-positive patients was higher than that(11.11%)in H.pylori-negative patients(P0.05).34 cases(54.84%)with gastric bezoars were complicated with ulcer.Most ulcer were gastric ulcer and they were mostly located in angle of stomach or antrum of stomach.The infection rate of H.pylori(64.71%,22/34)in gastric bezoars complicated by ulcer was higher than that(46.43%,13/28)in gastric bezoars not complicated by ulcer, but the difference between two groups was not statistically significant(P>0.05).Conclusion:Gastric bezoars are usually single,the size of most gastric bezoars is less than 5 cm,and gastric bezoars usually have

  7. Curative Effect Observation of Treating 17 Cases of Gastric Bezoar Department of Internal Medicine%17例胃石症内科治疗效果观察

    Institute of Scientific and Technical Information of China (English)

    曹月敏; 王琳; 吴淑彦

    2014-01-01

    目的:内科保守治疗胃石的疗效观察。方法选择我院2011年~2013年17例胃石患者(均为植物性胃石)口服口服多潘立酮10mg,3次/d,兰索拉唑30mg,1次/d,碳酸氢钠注射液20ml,4次/d,可口可乐150ml,6次/d,共用7d。结果14例患者结石消失,3例患者胃石变小,在胃镜下应用圈套器碎石治疗,治疗过程中,2例患者出现腹胀,恶心症状,无消化道出血及穿孔发生。结论内科保守治疗胃石患者痛苦小、费用较低,效果明显、值得推广。%Objective To observe the curative ef ect of conservative treatment of gastrolith Department of internal medicine. Methods Our hospital in the years 2011~2013 17 cases of gastrolith patients (al vegetable gastrolithiasis) oral domperidone 10 mg 3 times daily, lansoprazole 30 mg once daily, Sodium Bicarbonate Injection 20 ml, 4 times a day, Coca-Cola 150 mil iliters 6 times a day, a total of 7 days. Results 14 patients with gal stone disappeared, 3 cases gastric bezoar smal er, application of the snare lithotripsy under the endoscopy, the course of treatment, 2 patients with abdominal distention, nausea, no gastrointestinal hemorrhage and perforation. Conclusion Department of internal medicine, conservative treatment of bezoar pain in patients with small, low cost, obvious ef ect, worthy of promotion.

  8. The Preparation and Clinical Application study of Cow Bezoar and Borneol Mixture Double Releasing-control Membranes%复方双层缓释药膜的制备与临床应用研究

    Institute of Scientific and Technical Information of China (English)

    赵呈利; 孙迎东; 荣丽; 孙继军

    2014-01-01

    Objective:To prepare the Cow bezoar and Borneol mixture double releasing-control membranes and observe the effect on recurrent oral ulcer(ROU)patients. Method:The Cow bezoar and Borneolmixture double releasing-control membranes were used to ROU(patients). Result:The effective rates of the Cow bezoar and Borneol mixture double releasing-control membranes and the Mixed powder for raise and promote tissue regeneration group were 98%and 84%separately. Both groups were better than the control group(P<0.01). The Cow bezoar and Borneol mixture double releasing-control membranes were especially efficacious(P<0.05). Conclusion:The cow-bezoar and borneol mixture double releasing-control membranes can stop pain quickly and shorten the period of ulcer. It can raise the effect of clinical treatment and possess the values of popularization.%目的:对复方双层缓释药膜的制备及治疗复发性口腔溃疡的疗效观察分析。方法:复方双层缓释药膜制备、应用于复发性口腔溃疡病例。结果:复方双层缓释药膜为黄色半透明薄膜,有一定的韧性,具有明显的冰片及人工牛黄的清香气;复方双层缓释药膜、养阴生肌散组,总有效率分别达98%、84%,尤以复方双层缓释药膜临床效果良好,两组对比差异有统计学意义(P<0.05),且均显著优于对照组(P<0.01)。结论:该膜制备工艺简单,止痛迅速,对缩短溃疡期,促进愈合,提高临床治疗疗效非常确切,具有可行的临床应用推广价值。

  9. Quality research of Part Pediatric Paracetamol Atificial Cow-bezoar and Chlorphenamine Maleate Granules on the market%市场上部分小儿氨酚黄那敏颗粒的质量调研

    Institute of Scientific and Technical Information of China (English)

    郝晶晶; 李海亮; 李伟; 梁卓; 李金梅

    2013-01-01

    Objective To investigate the content uniformity of aceta minophen and chlorpheniramine maleate in Pediatric Paracetamol Atificial Cow-bezoar and Chlorphenamine Maleate Granules on the market. Methods Eight products of Pediatric Paracetamol Atificial Cow-bezoar and Chlorphenamine Maleate Granules on the market were sampled. The high performance liquid chromatography (HPLC) was used to measure the content uniformity of acetaminophen and chlorpheniramine maleate at the same time. Results Taking the content uniformity of acetaminophen and chlorpheniramine maleate as the measuring standards, the content uniformity of acetaminophen of 7 products was qualified and the content uniformity of chlorpheniramine maleate of 1 product was qualified. Conclusion Among the sampled products of Pediatric Paracetamol Atificial Cow-bezoar and Chlorphenamine Maleate Granules, only 1 product reaches the eligibility requirements.%目的 调研现市场上小儿氨酚黄那敏颗粒中对乙酰氨基酚和马来酸氯苯那敏的含量均匀度,考察该产品的质量情况.方法 通过抽查现市场上8个小儿氨酚黄那敏颗粒产品,采用高效液相色谱法(HPLC)同时测定对乙酰氨基酚和马来酸氯苯那敏的含量均匀度.结果 以对乙酰氨基酚和马来酸氯苯那敏的含量均匀度为衡量标准,有7个产品的对乙酰氨基酚的均匀度合格;有1个产品马来酸氯苯那敏的均匀度合格.结论 所抽查的小儿氨酚黄那敏颗粒质量只有1个达到合格要求.

  10. Determination of Related Substances in Pediatric Paracetamol Artificial Cow-bezoar and Chlorphenamine Maleate Granules by HPLC%HPLC法测定小儿氨酚黄那敏颗粒有关物质

    Institute of Scientific and Technical Information of China (English)

    杨春梅

    2014-01-01

    目的::建立HPLC法测定小儿氨酚黄那敏颗粒中对氨基酚的含量。方法:色谱柱CAPCELL PAK MGⅡC18色谱柱(150 mm ×4.6 mm,5μm),以0.05%醋酸铵溶液-甲醇(85∶15)为流动相,检测波长为232 nm,进样量:10μl,柱温:30℃,流速为1 ml·min-1。结果:对氨基酚在9.8784~197.5680 ng范围内与峰面积呈良好的线性关系(r =0.9991),平均回收率99.8%(RSD =0.9%,n =9),检测限为2 ng。结论:该方法简便,专属性强,准确可靠,可作为小儿氨酚黄那敏颗粒中有关物质的测定。%Objective:To establish an HPLC method for the determination of p-aminophenol in pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate granules. Methods: A CAPCELL PAK MGⅡC18 (150 mm × 4. 6 mm,5 μm) chromatographic column was used with 0. 05% ammonium acetate solution-methyl (85∶ 15) as the mobile phase at the flow rate of 1 ml·min-1 , the detection wavelength was 232nm,the injection volume was 10μl,and the column temperature was 30℃. Results:The linear range of p-aminophenol was 9. 878 4-197. 568 0 ng(r = 0. 999 1), the average recovery was 99. 8%(RSD = 0. 9%,n= 9), and detection limit was 2ng. Conclusion:The method is simple, specific and accurate, which can be used to determine the contents related substances in of pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate granules.

  11. 高效液相色谱法测定氨咖黄敏胶囊的含量%Determination in Paracetamol Caffein Artificial Cow-Bezoar and Chlorphenamine Maleate Capsules by HPLC

    Institute of Scientific and Technical Information of China (English)

    吴俊芳; 张涛; 李丽萍

    2011-01-01

    Objective To establish a HPLC method for simultaneously determining paracetamol and caffiene in Paracetamol Caffein Artificial Cow-Bezoar and Chlorpbenamine Maleate Capsules. Methods The analytical column was Aglient C18(250 mm ×4. 6 mm, 0. 5 μm) with the column temperature of 30 ℃. The mobile phase was 1% acetic acid (adjusting to pH 3. 7 with ethylenediamine)-methanol(60:40) with flow rate of 1.0 mL/min. The detection wavelength was set at 272 nm. Results The linear ranges of paracetanol and caffeine were 0.1222-3. 055 5 μg and 0. 007 482 - 0. 187 1 μg with the relative coefficient r = 1. 000 0, r = 1. 000 0 ( n = 6), respectively. The average recovery rates of paracetamol and caffeine were 99. 54% ( RSD =0.66% )and 100.43% ( RSD =0. 92% ), respectively. Conclusion The method is simple, rapid, accurate and reliable, which can be used for the quality control of Paracetamol Caffein Artificial Cow- Bezoar and Chlorpbenamine Maleate Capsules.%目的 建立同时测定氨咖黄敏胶囊中对乙酰氨基酚和咖啡因含量的高效液相色谱法.方法 色谱柱为Aglient C18柱(250 mm×4.6 mm,5μm),流动相为1%醋酸溶液(用乙二胺调Ph至3.7)-甲醇(60:40),流速为1.0 Ml/min,检测波长272 nm,柱温30℃.结果 对乙酰氨基酚、咖啡因进样量分别在0.122 2~3.055 5μg和0.007 482~0.1871μg范围内与峰面积呈良好线性关系,r分别为1.000 0和1.000 0(n=6),平均加样回收率分别为99.54%(RSD=0.66%)和100.43%(RSD=0.92%).结论 该方法快速简便、准确可靠,可用于氨咖黄敏胶囊的质量控制.

  12. 氨咖黄敏片中对乙酰氨基酚的溶出度测定%Dissolution determination of acetaminophen from paracetamol,caffein,ar-tificial cow-bezoar and chlophenamine maleate tablets

    Institute of Scientific and Technical Information of China (English)

    吴静芳

    2015-01-01

    目的:建立氨咖黄敏片中对乙酰氨基酚的溶出度测定方法。方法采用桨法,以900 ml水作为溶出介质,转速为50 r/min,以高效液相色谱法测定。采用C18柱,以乙腈-水-三乙胺(15:85:1.5)(用磷酸调pH至3.0)为流动相,检测波长为243 nm。结果对乙酰氨基酚在0.0625~0.3750 mg/ml的范围内呈现良好的线性关系(r=0.9995),平均回收率为100.1%,R SD值为0.39%(n=9)。样品溶出均一性好,在30 min时6片中对乙酰氨基酚的溶出度均达90%以上。结论本方法快速、简便、结果准确,可作为该制剂中对乙酰氨基酚的溶出度测定方法。%Objective To establish a dissolution determination method of acetaminophen from paracetamol,caffein,artifi-cial cow-bezoar and chlophenamine maleate tablets. Methods The paddle method was used and with 900 ml water as dissolution medium at the rotation speed of 50 r/min,the acetaminophen was determined by HPLC.The C18 column was used with the mobile phase of acetonitrile-water-triethylamine(15:85:1.5)(pH was adjusted to 3.0 by phosphoric acid)at the detection wavelength of 243 nm. Results The linear range of acetaminophen was 0.0625-0.3750 mg/ml (r=0.9995), the average recovery (n=9)was 100.1%(RSD=0.39%).The sample was dissolved uniformly,and the solubilities of the 6 tablets were above 90%. Conclusion The method is rapid,simple and accurate for dissolution determination of ac-etaminophen from paracetamol,caffein,artificial cow-bezoar and chlophenamine maleate tablets.

  13. THE EFFECT OF COW-BEZOAR ON DNA DAMAGE OF ICR MICE DUE TO TCE%牛黄对三氯乙烯致ICR小鼠DNA损伤的影响

    Institute of Scientific and Technical Information of China (English)

    邰昌松; 黎燕; 杨青; 沈惠麒

    2004-01-01

    目的:研究牛黄(Cow-bezoar)对三氯乙烯(TCE)致ICR小鼠肝肾外周血细胞DNA损伤的影响.方法:应用单细胞凝胶电泳(SCGE)技术和彗星图象分析系统,检测三氯乙烯对ICR小鼠肝肾外周血细胞DNA损伤作用,同时观察20~200μmol/L牛黄对三氯乙烯所致DNA损伤的保护作用.结果:TCE染毒组肝、肾、血细胞彗星率较阴性对照组增加;牛黄各组肝、肾、血细胞尾长、尾/头(长)、尾/头(光强)、尾DNA%、Oliver尾矩、彗星率减少.结论:牛黄能抑制三氯乙烯致ICR小鼠肝肾外周血细胞的DNA断裂能力.

  14. 1.4%Sodium Bicarbonate Retention Enema on Scavenging Channel Bezoars in Contrast to Digest%1.4%的碳酸氢钠保留灌肠清除小儿下消化道粪石对比研究

    Institute of Scientific and Technical Information of China (English)

    谢立新

    2014-01-01

    Objective To investigate the 1.4% sodium bicarbonate retention enema on road bezoar clear under the ef ect of digestion in children. Methods 70 patients in our department from 2012 January to selection method in 2013 December during hospitalization as evaluation object, Were randomly divided into experimental group and control group, two groups were given conventional anti infection,Spectrum ir adiation for two times a day to promote intestinal peristalsis, The experimental group adopted the first 1.4%sodium bicarbonate retention enema for half an hour after reflux enema once a day, The control group adopted reflux enema once a day, to compare the treatment ef ect of the two groups. Results The experimental group remove bezoar is bet er than the control group, The experimental group of independent defecation time earlier than the control group ( <0.5). Conclusion Sodium bicarbonate retention enema for half an hour after reflux enema than simple reflux enema can accelerate the bezoar ileus bezoar discharge, Reduce the bezoar ileus complications, reduce the conservative treatment is invalid for the incidence of operation, Shorten the hospitalization time, improve the cure rate of bezoar ileus.%目的探讨1.4%的碳酸氢钠保留灌肠对清除小儿下消化道粪石的效果。方法选取我科2012年1月~2013年12月期间住院的70例患儿作为评估对象,随机分为实验组及对照组,两组均给予常规抗感染,频谱仪照射2次/d促进肠蠕动,实验组采取先1.4%的碳酸氢钠保留灌肠30min后再回流灌肠1次/d,对照组采取回流灌肠1次/d,对两组的治疗效果进行对比分析。结果实验组清除粪石的效果优于对照组,实验组自主排便的时间早于对照组﹙<0.5﹚。结论碳酸氢钠保留灌肠30min后再回流灌肠比单纯回流灌肠更能加快粪石性肠梗阻的粪石排出,降低粪石性肠梗阻的并发症的发生,减少因保守治疗无效需做手术的发病率,缩短住院时间,提

  15. Clinical Observation of 35 Cases of Chronic Severe Hepatitis Treated with Traditional Chinese Medicine Enema and Ann Palace Bezoar Bolus%中药灌肠配合安宫牛黄丸治疗慢性重型肝炎35例临床观察

    Institute of Scientific and Technical Information of China (English)

    李斌

    2015-01-01

    目的:总结中药灌肠配合安宫牛黄丸治疗慢性重型肝炎的临床疗效。分析中药灌肠配合安宫牛黄丸治疗慢性重型肝炎的特色优势。方法:回顾性分析35例慢性重型肝炎的临床资料。结果:中药灌肠配合安宫牛黄丸治疗组35例中好转治愈22例(62.8%),死亡加未愈13例(37.2%);西药组33例中好转治愈15(45.5%),死亡加未愈18例(54.5%)。结论:中药灌肠配合安宫牛黄丸治疗慢性重型肝炎在提高临床疗效,减少内毒素血症,减少并发症,降低病死率等方面有特色优势。%Objective:To summarize the clinical curative effect of traditional Chinese medicine enema and Ann palace bezoar bolus on treatment of chronic severe hepatitis and analyze the special advantage of the method. Methods: The clinical data of 35 cases of chronic severe hepatitis was retrospectively analyzed.Results:In the 35 cases treated with traditional Chinese medicine enema and Ann palace bezoar bolus of the treatment group,22 (62.8%) cases were cured or become better,and 13 (37.2%) cases died or were not cured;in the 33 cases treated western medicine,15 (45.5%) were cured or become better, and 18 (54.5%) cases died or were not cured. Conclusion: In improving clinical curative effect, reducing endotoxemia,complications and fatality rate,traditional Chinese medicine enema and Ann palace bezoar bolus had special advantages.

  16. 人工牛黄甲硝唑胶囊联合云南白药治疗复发性口腔溃疡的临床观察%Clinical observation of the treatment of recurrent oral ulcer by artificial cow-bezoar and metronidazole capsules combined with yunnan baiyao

    Institute of Scientific and Technical Information of China (English)

    罗建红

    2016-01-01

    ObjectiveTo observe the effect of artificial cow-bezoar and metronidazole capsules combined with yunnan baiyao on the treatment of recurrent oral ulcer.Methods80 patients with recurrent oral ulcer were randomly assigned into treatment group and control group. The treatment group was treated by oral administration of artificial cow-bezoar metronidazole capsules and external use of Yunnan baiyao white powder, and the control group was treated by sublingual administration of cydiodine buccal tablets. The clinical curative effects and the av-erage healing, average symptoms disappear and average recurrence time were compared between these two groups. ResultsThe oral ulcer healed faster in the treatment group, the pain symptoms was obviously relieved, and the recurrence interval was extended. No adverse reaction was observed. The clinical curative effect was better than the control group(P<0.05). ConclusionThe artificial cow-bezoar metronidazole capsules combined with yun-nan baiyao had safe and effective effects on the treatment of recurrent oral ulcer by intemal and external use. It is worthy of further promotion and application in clinic.%目的:观察人工牛黄甲硝唑胶囊联合云南白药治疗复发性口腔溃疡的临床效果。方法选取复发性口腔溃疡患者80例,随机分成2组,观察组给予人工牛黄甲硝唑胶囊口服及云南白药粉外用,对照组给予华素片含服。比较2组的临床疗效及平均愈合、平均症状消失和平均复发时间。结果观察组经治疗后溃疡愈合快,疼痛症状缓解明显,复发间隔时间延长,无不良反应,优于对照组(P<0.05)。结论人工牛黄甲硝唑胶囊联合云南白药治疗复发性口腔溃疡,内服加外用安全且疗效显著,值得在临床上进一步推广和应用。

  17. Study on Pediatric Paracetamol Artificial Cow-bezoar and Chlorphenamine Maleate Tablets%不同厂家小儿氨酚黄那敏片溶出行为的考察

    Institute of Scientific and Technical Information of China (English)

    孙婷; 苗会娟; 张轶华

    2014-01-01

    目的:建立小儿氨酚黄那敏片溶出行为测定方法,考察制剂中对乙酰氨基酚的溶出行为。方法:采用转蓝法,以水900 mL为溶出介质,75转/min。色谱条件:Diamonsil C18色谱柱(4.6 mm ×200 mm,5μm),流动相:以磷酸盐缓冲液(取磷酸二氢铵11.5 g,加水适量使溶解,加磷酸1 mL,用水稀释至1000 mL)-乙腈(75∶25);检测波长:262 nm;柱温:30℃;进样量:10μL;流速:1.0 mL・ min-1。结果:采用该测定方法,考察17个厂家67批次样品的溶出行为,并对 AV(average value)值进行比较分析。研究发现小儿氨酚黄那敏片的溶出行为差异较大,无整体相似。结论:建立的小儿氨酚黄那敏片溶出度及高效液相色谱(HPLC)测定方法操作简单,重现性好,可使企业重视药品的溶出行为,提高药品的内在质量。%Objective: To establish a test method for the dissolution of pediatric paracetamol artificial cow-bezoar and chlorphenamine maleate tablets,and reseach curve of resolution.Methods: The method of dissolution was apparatus 1,the medium was water.And the chro-matographic condition of column was Diamonsil C18 (4.6 mm ×200 mm,5 μm), the mobile phase was phosphate buffer-acetonile (75∶25), the wavelength was 262 nm.Results: Research resolution curve of pediatric paracetamol of 67 batches in 17 companies, and analysis AV.The result shows that there are obvious difference on dissolution curve.Conclusion: The dissolution test method is accurate and widely applicable.

  18. Rektal bezoar forårsaget af solsikkekerner

    DEFF Research Database (Denmark)

    Thing, Birthe Agergaard; Jørgensen, Henrik

    2010-01-01

    Phytobezoar is a rare cause of colonic obstruction in Denmark. We describe a case of a 12-year-old boy who was admitted to the hospital because he had not passed stool in two days and complained of anal pain. The boy had consumed about 200 grams of salted sunflower seeds with shells two days before...

  19. Candida Bezoars with Urinary Tract Obstruction in Two Women without Immunocompromising Conditions

    Directory of Open Access Journals (Sweden)

    Giuseppe Di Paola

    2011-01-01

    Full Text Available More than half of the cases of fungal infections of the urinary tract are caused by Candida sp., but occurrence of obstructive uropathy caused by mycetomas or fungus balls (urobezoars is extremely rare. The latter are conglomerates of fungal hyphae. Diabetes mellitus, immunosuppression, chronic disease, and malignancies are known predisposing factors. Preoperative imaging is not pathognomonic; blood clots, radiolucent urinary calculi, air bubbles, and inflammatory debris can mimic urobezoars. We report on two otherwise healthy women presenting with urinary tract obstruction caused by candidal mycetomas of the renal pelvis that mimicked matrix lithiasis.

  20. Trichobezoars Detected and Treated Based on Plain Radiography.

    Science.gov (United States)

    Barrows, Amy; Vachon, Tyler; Campin, Richard C; Ignacio, Romeo C

    2015-10-01

    Bezoars are conglomerations of indigestible material that become trapped in the gastrointestinal tract. We present a case of an 8-year-old female child diagnosed with a gastric bezoar solely on plain radiography and treated with abdominal surgical exploration and removal. In addition, traditional characteristic radiographic findings and treatment options for bezoars found in the current literature are reviewed.

  1. 复方冰黄双层缓释药膜的应用研究%Application of Cow bezoar and Borneol mixture double releasing-control membranes

    Institute of Scientific and Technical Information of China (English)

    赵呈利; 孙迎东; 王爱芹; 舒静媛; 荣丽

    2007-01-01

    目的 观察复方冰黄双层缓释药膜治疗复发性口腔溃疡的疗效.方法 应用复方冰黄双层缓释药膜和养阴生肌散分别治疗复发性口腔溃疡病例,观察其疗效.结果 复方冰黄双层缓释药膜、养阴生肌散组,总有效率分别达100%、86%,差异有显著性(P<0.05),均优于对照组(P<O.01).结论 复方冰黄双层缓释药膜止痛迅速,可缩短溃疡期,促进愈合.

  2. Improvement of Identification Method of Artificial Cow-bezoar in Compound Preparations%复方制剂中人工牛黄鉴定方法的改进

    Institute of Scientific and Technical Information of China (English)

    李慧; 李淑芹; 崔桂君; 田瑶

    2003-01-01

    @@ 人工牛黄[1]具有清心解毒、解热抗炎作用,许多复方制剂中都含有它.在实际工作中我们发现,在不同药品中它们检验方法有所不同,而且有的药品检验中出现的结果与标准有很大的差别,极易误导检验人员做出不符合规定的错误结论,为此,我们通过对硫酸溶液浓度和体积的改变,使反应结果较为满意.

  3. Study on Detecting the Quantity of Man-made Cow-bezoar%人工牛黄的质量分析研究

    Institute of Scientific and Technical Information of China (English)

    杨洪武; 李晓; 辛敏通; 王平; 康廷国

    2003-01-01

    目的:检测不同厂家生产的人工牛黄的质量.方法:依照中华人民共和国部颁标准,采用试管法、薄层色谱法、紫外分光光度法对人工牛黄进行定性、定量的测定.结论:部颁标准能够很好的控制人工牛黄的质量,为含人工牛黄的中成药质量标准研究提供了确切的依据.

  4. 牛黄复方制剂中化学成分的研究%Study on the chemistry composition in compound cow- bezoar prescription

    Institute of Scientific and Technical Information of China (English)

    周凌; 吴晓莉; 王殿一

    2008-01-01

    目的:研究牛黄复方制剂中的化学成分;方法:采用TCL法观察复方样品液、阳性对照药材、含药血清、空白血清在薄层上的结果,并进行对比分析;结果与结论:赤芍药、栀子成分可能入血,复方样品液还有除阳性对照药材以外的成分,血清中没有黄连成分,实验中没有发现黄连素、蒽醌类.

  5. Literature analysis of the bad reaction of scene that cow bezoar detoxifies%牛黄解毒片不良反应文献分析

    Institute of Scientific and Technical Information of China (English)

    赵娟; 刘朝江

    2008-01-01

    目的 了解牛黄解毒片不良反应发生的情况.方法 通过对近年来国内公开发表医学期刊中有关牛黄解毒片的不良反应文献14篇,共24例进行统计分析.结果 24例牛黄解毒片引起的不良反应主要表现为药疹、过敏性休克,其次是皮肤、泌尿系统.结论 牛黄解毒片引起的不良反应,应大力加强有关中药安全用药知识的普及,规范临床合理应用,提高中药制剂质量,实施对中药制剂不良反应的控制、监测.

  6. Identification and Determination of Artificial Cow-Bezoar in Houjiling Tablets%喉疾灵片中人工牛黄的检测

    Institute of Scientific and Technical Information of China (English)

    吴泽君; 张国浩; 胡冠羽; 陈国平; 刘坦

    2006-01-01

    建立喉疾灵片中人工牛黄的质量控制方法.采用薄层色谱法鉴别人工牛黄特征成分贝斯素,方法简单、专属性强.高效液相色谱法测定胆红素的含量.采用DiamonsilTM C18色谱柱,流动相为甲醇-氯仿-1%磷酸(81∶13∶6),流速为1.4 ml·min-1,检测波长为450nm.胆红素的线性范围为0.01589~0.1589μg,r=0.9993;平均回收率为96.20%,RSD为1.61%(n=9).本方法可用于喉疾灵片的质量控制.

  7. Quality analysis for paracetamol, caffein, atificial cow-bezoar and chlorphenamine maleate capsules%氨咖黄敏胶囊的质量分析

    Institute of Scientific and Technical Information of China (English)

    丁苏苏; 李倚云; 王威; 凌真

    2013-01-01

    目的:评价氨咖黄敏胶囊的总体质量和现行质量标准的可行性.方法:通过对氨咖黄敏胶囊的现行法定标准检验和探索性研究检验综合评价其质量状况.结果:本次评价性抽样共检验氨咖黄敏胶囊103批,按现行法定标准检验,合格率为100.0%;通过探索性研究检验,合格率仅为32.0%.结论:通过评价发现,氨咖黄敏胶囊按现行标准检验总体质量良好.但现行标准项目设置简单,不能全面有效控制药品质量,有必要进一步提高质量标准.

  8. Giant gastric trichobezoar in a young female.

    Science.gov (United States)

    Ibuowo, Abdulrazaq Akin; Saad, Anwar; Okonkwo, Thomas

    2008-12-01

    Bezoars are concretions of undigested matter in the gastrointestinal tract (GIT), most commonly in the stomach. The main predispositions to bezoar formation are, altered GIT anatomy or disordered GIT motility/physiology. Clinically, bezoars are classified according to their predominant component. Trichobezoars (composed mainly of hair) as a clinical entity are almost always associated with an underlying psychiatric disorder. We present below a case of giant gastric trichobezoar in a young female which was treated by gastrostomy and excision of the mass.

  9. Drug: D06721 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available attle family) Oriental bezoar Major component: Bile acid [CPD:C01558] Powdered product: Standards for non-pharmacopoeial crude drugs... Therapeutic category of drugs in Japan [BR:br08301] 5 Crude drugs... and Chinese medicine formulations 51 Crude drugs 510 Crude drugs 5100 Crude drugs D06721 Oriental ...bezoar (JP16) Traditional Chinese Medicine in Japan [BR:br08304] Crude Drugs Other drugs Drugs for resuscita...tion D06721 Oriental bezoar Crude drugs [BR:br08305] Animals Mammals D06721 Oriental bezoar PubChem: 47208372 ...

  10. Small bowel obstruction attributable to phytobezoar

    Science.gov (United States)

    Razavianzadeh, Nasrin; Foroutan, Behzad; Honarvar, Farhad; Forozeshfard, Mohammad

    2016-01-01

    Small bowel obstruction (SBO) is a common condition encountered in surgical practice. Literature shows divers and many different etiologies for intestinal obstruction. However, bezoars are rarely reported as an etiological factor. A bezoar happens most commonly in patients with impaired gastrointestinal motility. There are four types of bezoars: phytobezoars, trichobezoars, pharmacobezoars and lactobezoars. The most common type is phytobezoars, which are composed of undigested fiber from vegetables or fruits especially persimmons. They are mostly composed of cellulose, tannin and lignin. The commonest phytobezoar reported worldwide is related to the persimmon fruit ingestion. The most common symptom of bezoar-induced SBO is abdominal pain (96–100%). Other common symptoms include nausea and vomiting. Primary small bowel phytobezoars almost always present as SBO. We present an unusual case of SBO caused by a phytobezoar in a 35-year-old patient. Many types of bezoar can be removed endoscopically, but some will require operative intervention. PMID:28031856

  11. HPLC determination of bilirubin in paracetamol, caffein, atificial cow -bezoar and chlorphenamine maleate tablets%高效液相色谱法测定氨咖黄敏片中胆红素的含量

    Institute of Scientific and Technical Information of China (English)

    梁云霞; 李杰滨; 谭秀敏; 谭博; 赵悦辉

    2007-01-01

    目的:采用高效液相色谱法对氨咖黄敏片中胆红素进行含量测定.方法:选用Agilent C18分析柱,甲醇-氯仿-1%磷酸溶液(80:12:8)为流动相,检测波长为449 nm,流速1.0 ml/min,柱温30 ℃.结果:胆红素的线性范围为0.008~0.083 μg(r=1.000),平均回收率100.2%.结论:方法准确,回收率好.

  12. HPLC法测定氨咖黄敏胶囊中咖啡因含量%Study on quantitatire determination of caffeine from paracetamol caffein atificial cow-bezoar and chlorphenamine maleate capules

    Institute of Scientific and Technical Information of China (English)

    刘锦平; 王俊

    2004-01-01

    目的探讨氨咖黄敏胶囊中咖啡因的含量测定方法.方法采用高效液相色谱法(HPLC法),用C18柱以磷酸二氢钾溶液-甲醇(80:20)为流动相,检测波长215 nm.结果咖啡因浓度在0.06~0.14 g·L-1间线性关系良好,r=0.999 9,平均回收率为99.9%.结论用HPLC方法测定氨咖黄敏胶囊中咖啡因含量,方法简捷,结果准确,专属性强.

  13. 《伤寒杂病论》中麻黄与石膏配伍规律探讨%Exploration on the Compatibility of Cow-bezoare and Gypsum in the "Treatise on Febrile and Miscellaneous Diseases"

    Institute of Scientific and Technical Information of China (English)

    徐伟辉; 龚高柏

    2001-01-01

    @@ 张仲景载方314首,其中麻黄、石膏同用之方有麻杏石甘汤、大青龙汤、桂枝二越婢一汤、麻黄升麻汤、越婢汤、越婢加半夏汤、越婢加术汤、小青龙加石膏汤、麻黄厚朴汤等9方.纵观仲景将辛温之麻黄与甘寒之石膏同用,不外乎治疗表寒里热证、上寒下热证、寒轻热重证、寒重热轻证等,均系寒热错杂之证.然细揣摩,由于方中麻黄、石膏用量不同,君臣佐使作用不一,故其功效迥异.笔者不揣浅陋,特作探讨如下.

  14. Experimental Study on Pharmacologic of Musk Cow-bezoare Pill(麝香牛黄丸)%麝香牛黄丸药理作用实验研究

    Institute of Scientific and Technical Information of China (English)

    张蕻; 张丽; 朴晋华; 高天红; 宋守财; 范永强; 卢建亚

    2003-01-01

    目的:探讨麝香牛黄丸解热、抗炎、止咳的功效.方法:选合格大、小鼠分别造发热、肿胀及咳嗽模型,并采用麝香牛黄丸治疗.结果:麝香牛黄丸对酵母致热大鼠有解热作用;对大鼠蛋清、角叉菜胶足跖肿和小鼠二甲苯耳肿胀有明显的抗炎作用,对大鼠棉球肉芽肿的形成有一定的抑制作用,并能减轻氨水导致的咳嗽.结论:麝香牛黄丸具有清热、抗炎、止咳作用.

  15. One Case of Allergic Response Induced by Sulfmethoxazole,Trimethoprim,Boneol and Artificial Cow-bezoar Tablets%磺啶冰黄片致过敏反应1例

    Institute of Scientific and Technical Information of China (English)

    张岩

    2010-01-01

    @@ 病例:患者,女,51岁.2009年6月17日于我院妇科门诊定期体检,诊断为尿路细菌感染.患者既往无药物过敏史,无高血压病、糖尿病及其他疾病史.查体:体温36.8℃,脉搏76次/分,血压132/79 mmHg(1 mmHg=0.133kPa),心肺听诊无异常,腹软,余无异常.实验室检查:尿常规脓细胞(+++),其他指标无明显异常.门诊医生予磺啶冰黄片(广东彼迪药业有限公司,批号:20090301)每次2片,1天2次,口服抗菌治疗.患者当晚口服磺啶冰黄片1次(2片),感胃部不适,恶心,全身瘙痒.6月18日,患者晨饭后再次口服磺啶冰黄片1次(2片),1小时后,患者感头痛、头晕,恶心、呕吐,呕吐物为胃内容物,伴全身瘙痒难忍.

  16. 心胃同病与心胃同治探究%Clinical study on treatment of inflammation of the throat due to wind- heat with cow- bezoar compound prescripition pharmaceutics

    Institute of Scientific and Technical Information of China (English)

    鲁燕侠; 蔺兴遥; 崔佳; 逯振宇

    2003-01-01

    阐明了"心胃同病"与"心胃同治"的概念,提出了由"心胃同病"与"心胃同治"引发的在临床与药物研发中遇到的问题,并就"心胃同病"与"心胃同治"的理论基础及其现代研究进展,"心胃同治"思路与方法探讨,"心胃同治"方药研究思路与方法等问题提出了自己的观点.

  17. Protective effect of bilirubin and natural cow - bezoar on styrene - induced HepG2 cell DNA strand breaks%胆红素及牛黄拮抗苯乙烯所致肝癌细胞株损伤

    Institute of Scientific and Technical Information of China (English)

    魏雪涛; 蒋建军; 尚兰琴; 沈惠麒

    2004-01-01

    目的观察苯乙烯诱导的人肝癌细胞株(HepG2)细胞DNA链断裂损伤以及天然牛黄和胆红素对其损伤的拮抗效应.方法采用单细胞凝胶电泳法观察HepG2细胞体外暴露于苯乙烯出现的DNA链断裂损伤,同时观察天然牛黄和胆红素对于苯乙烯诱导DNA损伤的拮抗作用.结果在细胞存活未受到苯乙烯影响的浓度下,0.2μmol/L的苯乙烯即可诱导HepG2细胞明显的DNA链断裂损伤,彗星细胞频率和DNA迁移距离分别为(9.5±2.1)%和(4.5±0.7)μm.在明显诱导DNA损伤浓度的苯乙烯处理时同时加入天然牛黄或胆红素,发现二者对苯乙烯诱导的DNA链断裂损伤在一定浓度下均有良好的拮抗作用,10 μmol/L的胆红素或天然牛黄与1μmol/L的苯乙烯共同处理时,HepG2细胞的DNA损伤水平基本回复到本底水平.结论苯乙烯能够诱导HepG2细胞出现DNA链断裂损伤,10 μmol/L的胆红素或天然牛黄基本能完全拮抗苯乙烯诱导的DNA链断裂损伤.

  18. Content determination of two components in paracetamol, caffeine, artificial cow-bezoar and chlorphenamine maleate capsules by HPLC%HPLC法同时测定氨咖黄敏胶囊中二组分的含量

    Institute of Scientific and Technical Information of China (English)

    邹燕; 程爱平; 林灿

    2015-01-01

    目的 建立高效液相色谱法同时测定氨咖黄敏胶囊中对乙酰氨基酚、咖啡因2种成分的含量.方法 采用Agilent extend-C18(150 mm ×4.6 mm,5μm)色谱柱,流动相为乙腈(A)-三乙胺溶液(1mL三乙胺加79 mL水,调pH至3.1,B)(17∶83),流速1.0 mL/min,检测波长217 nm;柱温25℃,进样量15 μL.结果 对乙酰氨基酚、咖啡因的线性浓度范围分别为831.33 ~2 078.33 μg/mL(r=0.999 6)和50.27 ~ 125.67 μg/mL(r =0.999 4),两组分平均回收率分别为99.99% (RSD=0.02%)和100.14%(RSD=0.52%).结论 该方法灵敏度、准确度高,重复性好,适用于氨咖黄敏胶囊中对乙酰氨基酚和咖啡因2种有效成分的测定.

  19. Evaluation for the Quality of Paraletamol Caffeine Eartificial Cow-bezoar and Chlorphenamine Maleate Capsules with Pattern Recognition%用模式识别法对氨咖黄敏胶囊进行再评价

    Institute of Scientific and Technical Information of China (English)

    马玉荣; 孙志强

    2008-01-01

    用模糊聚类分析的原理和模式识别方法,对2004~2006年近3年来全国抽验的氨咖黄敏胶囊质量进行进一步分析和评价.选择氨咖黄敏胶囊检查项目中对乙酰氨基酚含量A(%)、咖啡因含量B(%)、重量差异C(RSD%)、崩解时限D(min)4个检验指标,采用模糊聚类分析的方法,将符合药品标准规定的116批样品进一步分为Ⅰ、Ⅱ、Ⅲ 3个等级.116批样品中Ⅰ(优)级品24批,约占20.7%;Ⅱ(良)级品81批,约占69.8%;Ⅲ(可)级品11批,约占9.5%.本品所采用的质量标准方法是可行的,能有效的控制其质量,对本品质量的提高具有促进作用.但是本品的优级品率较低,说明生产厂家需要进一步改进工艺,严格执行生产规程,努力提高产品质量.

  20. 氨咖黄敏片人工牛黄中的贝斯素薄层色谱鉴别%Identification for Beisisu of Artificial Cow-bezoar in Ankahuangmin Tablets by TLC

    Institute of Scientific and Technical Information of China (English)

    刘岚; 屈德扬

    2005-01-01

    目的:建立一种测定氨咖黄敏片人工牛黄中的贝斯素的薄层色谱鉴别方法.方法:采用TLC鉴别方法.结果:通过改变提取方法和展开剂获得清晰、持久的TLC图谱.结论:本法简便,灵敏,准确,重现性好,能有效地控制氨咖黄敏片的质量.

  1. Determination of related substances of pediatric paracetamol, artificial cow-bezoar and chlorphenamine maleate granules by LC-MS/MS%LC-MS/MS法测定小儿氨酚黄那敏颗粒中的有关物质

    Institute of Scientific and Technical Information of China (English)

    张轶华; 张西如; 张玉; 韩彬; 姜建国

    2014-01-01

    目的 用HPLC测定小儿氨酚黄那敏颗粒中的有关物质,并采用液质联用技术分析其共性及特性的未知杂质.方法 采用Diamonsil C18色谱柱(200mm×4.6mm,5μm),流动相为磷酸盐缓冲液-乙腈(75∶25),检测波长262 nm,柱温30℃,进样量10 μL,流速1.0 mL· min-1.LC-MS/MS采用Atlantis T3色谱柱(100mm×2.1 mm,5μm),流动相为乙腈-0.01 mol·L-1乙酸铵溶液(冰乙酸调pH2.8)(25∶75),柱温20℃,进样量10 μL,离子源为ESI源,正离子扫描.结果 样品中各成分的分离度可满足有关物质限度的要求,通过分析二级质谱图,确定了未知杂质的来源与结构.结论 建立的HPLC测定方法灵敏、准确、专属性强,适用于测定小儿氨酚黄那敏颗粒中的有关物质;采用液质联用技术可推测未知物质可能的结构.

  2. Correlation of adverse events to arsenic in detoxicating tablets of cow-bezoar%牛黄解毒片的不良反应与砷相关性分析

    Institute of Scientific and Technical Information of China (English)

    王弘; 郭代红; 陈宜鸿; 裴保香; 陈超

    2005-01-01

    目的:分析牛黄解毒片不良反应产生的原因.方法:汇总近年来我院全军不良反应监测中心有关牛黄解毒片不良反应的一般资料以及表现,并分析其原因.结果:通过分析不良反应产生的原因,认为处方中所含矿物药雄黄中的砷引起,牛黄解毒片每克样品中含砷0.076 8 g,是中国药品检验标准操作规范2000年版中砷盐限量的38 400倍.结论:砷在人体内的生物半衰期长,因此提醒在使用时不要过量,乳妇应禁用,避免不合理应用造成对整体人群的伤害.

  3. 氯芬黄敏片中人工牛黄测定方法的改进%Assay Improvement of Man-made Cow-bezoar in Lüfen Huang Min Pian

    Institute of Scientific and Technical Information of China (English)

    孙成考; 梁培松; 张伟

    2004-01-01

    将氯芬黄敏片(感冒通片)人工牛黄测定过程中的加氯仿研磨改成加氯仿超声,改进前后测定结果对比表明此方法可行,为以后质量标准的修订提供了有益参考.

  4. The research of quantity test method of various components in succession medicinal substances of cow-bezoar%牛黄类药材各类成分定量检测方法研究概况

    Institute of Scientific and Technical Information of China (English)

    邹秦文; 石岩; 刘薇; 熊婧; 魏锋; 林瑞超; 马双成

    2015-01-01

    牛黄具有清心开窍、凉肝解毒、豁痰息风等功效,是名贵中药材之一.由于其资源紧缺,价格昂贵,我国于20世纪50年代中期即开始了替代品即培植牛黄、体外培育牛黄与人工牛黄的研究.本文主要对牛黄和它的替代品及其制剂中胆红素和胆汁酸类等成分的定量方法如分光光度法、薄层色谱法、高效液相色谱法和毛细管电泳法等进行综述,并进行了分析比较.

  5. HPLC法测定氨咖黄敏胶囊中人工牛黄的含量%HPLC determination of calculus bovis artifactus in paracetamol,caffeine,artificial cow-bezoar and chlorphenamine maleate capsules

    Institute of Scientific and Technical Information of China (English)

    郭丙炎; 胡翮; 邱蓓

    2009-01-01

    目的:建立氨咖黄敏胶囊中人工牛黄的HPLC含虽测定方法.方法:采用DiamonsilTM C18色谱柱(4.6 mm×250 mm,5μm),以四氢呋喃-乙腈-0.1%醋酸铵(pH 4.7)(42:22:36)为流动湘,流速1.0 mL·min-1,检测波长:452nm,柱温:35℃.结果:胆红素进样量在0.0232~0.465 μg范围内,与峰面积积分值呈良好的线性关系(r=0.9991),平均回收率(n=18)为99.9%.结论:HPLC法重复性好,且简便、易行,可用于氨咖黄敏胶囊剂中人工牛黄成分的检测.

  6. Assay of Paracetamol and Caffeine in Atificial Cow-bezoar and Chlorphenamine Mateate Capsules by HPLC%HPLC测定氨咖黄敏胶囊中对乙酰氨基酚和咖啡因的含量

    Institute of Scientific and Technical Information of China (English)

    白娟; 刘芳; 肖黎; 隋迎军

    2004-01-01

    目的建立同时测定氨咖黄敏胶囊中对乙酰氨基酚和咖啡因含量的高效液相色谱法.方法采用ODS柱,流动相:甲醇-水(40∶60),流速1.0ml/min,检测波长217nm,外标法计算.结果线性范围分别为对乙酰氨基酚120~800μg·ml-1,r=0.999 8;咖啡因12~80μg·ml-1,r=0.999 9,回收率分别为对乙酰氨基酚100.5%,RSD为0.2%,咖啡因99.8%,RSD为0.5%.结论本法分离效果好,辅料无干扰,快速、简便.

  7. 反向传播神经网络用于牛黄解毒片的质量评价研究%THE QUALITY VALUATION OF DETOXICATING TABLET WITH COW-BEZOAR BY BP NEURAL NETWORKS

    Institute of Scientific and Technical Information of China (English)

    夏保云; 冯鑫; 蔡文生; 印春生; 潘忠孝

    2000-01-01

    目的:研究中成药牛黄解毒片的质量评价方法.方法:应用反向传播神经网络(BP神经网络)模型.结果:该分类结果与其它经典方法一致,识别准确率为100%.结论:该方法具有较强的容错能力和较快的识别速度,简单易行,便于大规模的数据处理,也可用于其它中成药的质量评价.

  8. Determination of bilirubin in paracetamol,caffein, atificial cow-bezoar and chlorphenamine maleate capsules by RP-HPLC%氨咖黄敏胶囊中胆红素的含量测定

    Institute of Scientific and Technical Information of China (English)

    刘雁鸣; 郑金凤; 杨汉初

    2005-01-01

    目的采用反相高效液相色谱法测定氨咖黄敏胶囊中胆红素的含量.方法采用DiamonsilTMC18色谱柱(4.6 mm×200 mm,5μm),以甲醇-氯仿-1%磷酸溶液(85:13:2)为流动相,流速1.0 mL·min-1,检测波长450nm.结果胆红素在3.97~79.5μg·mL-1峰面积与浓度呈良好的线性关系(r=0.997),平均回收率为99.95%,RSD为0.38%(n=9).结论方法简便、精密度高、重现性好、结果准确可靠.

  9. 小儿氨酚黄那敏颗粒鉴别方法的改进%Improvement of Method of Iidentifying pediatric Paracetamol, Artificial cow-bezoar and chlorphenamine Maleate Granules

    Institute of Scientific and Technical Information of China (English)

    盖轲; 郑阿利; 齐慧丽

    2008-01-01

    目的 完善小儿氨酚黄那敏颗粒质量标准.方法 改进薄层色谱法对对乙酰氨基酚和马来酸氯苯的展开系统;采用薄层色谱法对人工牛黄中的胆酸、猪去氧胆酸进行鉴别,并采用分光光度法测定人工牛黄中胆红素的吸收峰.结果 薄层色谱鉴别方法专属性强;分光光度法简单,重现性好.结论 改进后的方法准确、快速地进行定性测定,可用于该制剂的质量控制.

  10. To change an identifying method on TLC of paracetamol,caffein,atificial cow-bezoar and chlorphenamine maleale capsules%氨咖黄敏胶囊薄层色谱鉴别方法的改进

    Institute of Scientific and Technical Information of China (English)

    吕长淮

    2006-01-01

    目的改进氨咖黄敏胶囊薄层色谱鉴别方法.方法采用TLC法对氨咖黄敏胶囊进行鉴别试验.结果 TLC法同时检出了氨咖黄敏胶囊中对乙酰氨基酚、咖啡因、马来酸氯苯那敏3种成分.结论改进后的方法简便、灵敏、可行,分离效果好.

  11. HPLC法测定氨咖黄敏胶囊中对乙酰氨基酚的含量%Determination of paracetamol in paracetamol,caffein,atificial cow-bezoar and chlorphenamine maleate capsules by HPLC

    Institute of Scientific and Technical Information of China (English)

    林娟; 陈自平

    2004-01-01

    目的建立氨咖黄敏胶囊中对乙酰氨基酚的含量测定方法.方法用十八烷基硅烷键合硅胶柱(300mm×3.9 mm),以磷酸盐缓冲液(取磷酸二氢钾6.8 g,用水溶解并稀释至1000ml,加三乙胺6 ml,用磷酸调节pH值为7.3±0.1):甲醇(80:20)为流动相,于246 nm波长处检测,建立HPLC测定法.结果线性范围为40.0~60.0 mg@L-1(r=0.999 9).平均回收率为100.2%,RSD=0.1%.结论 HPLC法操作简单,快捷,结果准确.

  12. Analysis of Adverse Reactions to Detoxicating Tablets(Pills)of Cow-bezoar in 40 Cases%牛黄解毒片(丸)40例不良反应分析

    Institute of Scientific and Technical Information of China (English)

    邹明畅; 倪鸿昌

    2007-01-01

    目的 分析牛黄解毒片(丸)所致的不良反应的一般规律及其特点,为临床合理用药提供参考.方法 对1994年1月-2006年6月国内公开发表的药学杂志刊登的有关牛黄解毒片(丸)所致40例不良反应进行分类统计与分析.结果 牛黄解毒片(丸)可致免疫系统、消化系统、泌尿系统等不良反应,最常见为过敏反应.结论 牛黄解毒片(丸)可引起一定的不良反应,临床需注意其合理使用.

  13. 小儿氨酚黄那敏片质量标准的完善%Improvement of the Quality Standard for Pediatric Paracetamol, Artificial Cow-bezoar and Chlorphenamine Maleate Tablets

    Institute of Scientific and Technical Information of China (English)

    孙莉; 黄明珍

    2008-01-01

    目的:完善小儿氨酚黄那敏片质量标准.方法:采用薄层色谱法对人工牛黄中的胆红素、贝斯素、胆酸、猪去氧胆酸进行鉴别;采用高效液相色谱法对小儿氨酚黄那敏片中对乙酰胺基酚和马来酸氯苯那敏进行含量测定.结果:薄层色谱鉴别方法专属性强;含量测定方法简便,重复性好.结论:建立的方法可准确、快速地进行定性、定量测定,可用于该制剂的质量控制.

  14. Ventrikelbezoar forårsaget af bariumsulfat

    DEFF Research Database (Denmark)

    Nielsen, Marie Kristina Rue; Ewertsen, Caroline; Hillingsø, Jens Georg

    2012-01-01

    We present the first case of a gastric bezoar caused by barium sulphate acting as an intermittently occluding mass in a patient who had undergone small bowel follow-through on suspicion of small bowel obstruction (SBO) after total pancreatectomy. The patient underwent acute surgery but intermittent...... symptoms of SBO persisted. A barium bezoar was seen on plain abdominal film and afterwards diluted and fragmented gastroscopically. A barium bezoar giving rise to SBO is a possible complication to barium follow-through in patients with impaired gastric transit time....

  15. [Two cases of phytobezoars treated by adminsitration of Coca-Cola by oral route].

    Science.gov (United States)

    Lee, Hyun Jai; Kang, Hyoun Goo; Park, Se Young; Yi, Chea Yong; Na, Gyoung Jun; Lee, Tae Yeong; Kim, Sang Hyun; Song, Chul Soo

    2006-12-01

    Bezoars are concretions of foreign bodies found in the gastrointestinal tract. In the past, most common method for the treatment of bezoar was surgical management. However, the current treatment methods include chemical dissolution and endoscopic mechanical lithotripsy. There were few reports on the treatment of phytobezoars by nasogastric Cola lavage. However, there was no report succeeded by oral route alone. In our two cases, phytobezoars were treated by oral administration of Coca-Cola. Our patients drank 700-800 mL of Coca-Cola daily, and after two months, complete dissolutions of bezoars were achieved. We report two cases of phytobezoars completely treated by drinking Coca-Cola.

  16. Environ: E00093 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available taurus [TAX:9913] Same as: D06721 Bovidae (Cattle family) Oriental bezoar Major component: Bile acid [CPD:C01558] Powdered product: Standards for non-pharmacopoeial crude drugs ...

  17. Phytobezoar: a recurring abdominal problem.

    Science.gov (United States)

    Hines, J R; Guerkink, R E; Gordon, R T; Weinermann, P

    1977-06-01

    Phytobezoars often follow gastric surgery for peptic ulcer disease. Billroth I resections have a high incidence of gastric bezoars, especially if accompanied by vagotomy. The larger opening of a Billroth II resection may result in intestinal bezoars with obstruction in the narrow terminal ileum. Gastric bezoars can be treated with enzymes or can be broken up by endoscopy; only rarely is operative removal required. Intestinal bezoars can be treated by long-tube and enzyme instillation but usually require laparotomy. If possible, the bolus should be milked into the cecum, but enterotomy or even resection may be required. Prevention is the best treatment and can be carried out by instructing patients who have had gastric surgery to avoid the fibrous portion of oranges and grapefruit and to avoid persimmons.

  18. Review of the diagnosis and management of gastrointestinalbezoars

    Institute of Scientific and Technical Information of China (English)

    Masaya Iwamuro; Hiroyuki Okada; Kazuhiro Matsueda; Tomoki Inaba; Chiaki Kusumoto; Atsushi Imagawa; Kazuhide Yamamoto

    2015-01-01

    The formation of a bezoar is a relatively infrequentdisorder that affects the gastrointestinal system.Bezoars are mainly classified into four types dependingon the material constituting the indigestible mass of thebezoar phytobezoars, trichobezoars, pharmacobezoars,and lactobezoars. Gastric bezoars often cause ulcerativelesions in the stomach and subsequent bleeding,whereas small intestinal bezoars present with smallbowel obstruction and ileus. A number of articles haveemphasized the usefulness of Coca-Cola? administrationfor the dissolution of phytobezoars. However, persimmonphytobezoars may be resistant to such dissolutiontreatment because of their harder consistency comparedto other types of phytobezoars. Better understanding ofthe etiology and epidemiology of each type of bezoarwill facilitate prompt diagnosis and management.Here we provide an overview of the prevalence, classification,predisposing factors, and manifestations ofbezoars. Diagnosis and management strategies arealso discussed, reviewing mainly our own case series.Recent progress in basic research regarding persimmonphytobezoars is also briefly reviewed.

  19. Endoscopic management of a new entity-plastobezoar: A case report and review of literature

    Institute of Scientific and Technical Information of China (English)

    SP Misra; Manisha Dwivedi; Vatsala Misra

    2006-01-01

    Foreign bodies and bezoars are commonly encountered in children. We describe a child aged 11 years who ingested large amounts of plastic material used for knitting chairs and charpoys. The conglomerate of plastic threads, entrapped food material and other debris,formed a huge mass occupying the whole stomach.Chronic irritation of the gastric antral mucosa led to ulceration and formation of hyperplastic polyps. We labeled this new entity as a "plastobezoar". The entire bezoar could be removed endoscopically.

  20. TRICHOBEZOAR

    Directory of Open Access Journals (Sweden)

    Sanjeev

    2013-11-01

    Full Text Available A bezoar is a mass of undigested material within the gastrointestinal tract and are classified according to the material of which they are composed (1. The term “bezoar” is derived from Arabic “badzehr” or from Persian “panzehr”, bot h meaning counter poison and antidote(2. Bezoar may be classified as Trichobezoar (mass of hair, Phytobezoar (vegetable fiber, Diospyrobezoar (persimmons, Lactobezoar (inspissated milk, Pharmacobezoar (tablets/semiliquid mass of drugs & miscellaneou

  1. TRICHOBEZOAR

    OpenAIRE

    2013-01-01

    A bezoar is a mass of undigested material within the gastrointestinal tract and are classified according to the material of which they are composed (1). The term “bezoar” is derived from Arabic “badzehr” or from Persian “panzehr”, bot h meaning counter poison and antidote(2). Bezoar may be classified as Trichobezoar (mass of hair), Phytobezoar (vegetable fiber), Diospyrobezoar (persimmons), Lactobezoar (inspissated milk), Pharmacobezoar (tablets/semiliquid mass of drugs) ...

  2. Extração de fitobezoar gástrico por videolaparoscopia: considerações técnicas originais Videolaparoscopic extraction of gastric phytobezoar: original technical aspects

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Domene

    2002-08-01

    Full Text Available Videolaparoscopic surgery has been used for treatment of almost all surgical abdominal diseases, mainly where there are no large ressections, or operative field is limited. In these situations, laparoscopic surgery has the advantages of less morbidity, quick recovery and good cosmetic results. Bezoars removal, or its mobilization, is probably included in these possible proceedings. Three non-laparotomic procedures were described: 1. endoscopic-laparoscopic; 2. videolaparoscopy and mobilization of intestinal bezoar to the cecum; 3. laparoscopy and gastrotomy for bezoar removal, through suprapubic incision or the umbilical punction. There have been only two publications describing the videolaparoscopic method for bezoar removal, and the methods applied can be complications or morbidity related. We describe one case where the applied technique is simple and easy to perform, time saving and probably less complications-related. This technique, with four trocars, utilized a plastic bag besides the stomach to be opened, followed by gastrotomy, bezoar removal and immediate introduction in the plastic bag, suture of gastrotomy and removal through the left subcostal trocar. This technique was feasible and easy to perform, with short operative time, and there were no intra or post-operative complications; the patient was discharged in the second post-operative day, and is without further problems after one year follow-up. We believe that this could be an adequate technique to perform laparoscopic gastric bezoar removal, and the rigid sequence of operative events allows a quick procedure, with minimal contamination. The videolaparoscopy seems to be an adequate access to surgical treatment of gastro-intestinal bezoars, with or without obstruction, and should be the ellected the procedure of choice to begin the surgical treatment, with convertion to laparotomy in case of any intra-operative adversity.

  3. 氨咖黄敏胶囊中咖啡因含量测定不确定度的报告%Report of uncertainty for the determination of caffeine in paracetamol caffeine Atificial cow-bezoar and chlorphemamine maleate capsules complex

    Institute of Scientific and Technical Information of China (English)

    朱玲; 汪民海

    2009-01-01

    目的 对氨咖黄敏胶囊中咖啡因含量测定结果的可信性、有效性,测量其不确定度.方法 通过分析测定过程和步骤,确定不确定度的来源,量化不确定度分量,计算合成不确定度和扩展不确定度.结果 建立了用碘量回滴法测定氨咖黄敏胶囊中咖啡因含量不确定度,计算各分量的不确定度,然后计算出合成不确定度为1.12×10-3,扩展不确定度为0.002.结论 为氨咖黄敏胶囊中咖啡因含量测定的可信度提供一种数学判断方法,对氨咖黄敏胶囊的质量控制具有指导意义.

  4. Pharmacokinetics of paracetamol and caffeine in paracetamol, caffeine, atificial cow-bezoar and chlorphenamine maleate capsules in healthy volunteers%氨咖黄敏胶囊中对乙酰氨基酚和咖啡因的人体药动学

    Institute of Scientific and Technical Information of China (English)

    程炜; 秦峰; 鹿秀梅; 毕玉金; 李发美

    2007-01-01

    目的 研究氨咖黄敏胶囊中对乙酰氨基酚和咖啡因的人体药动学.方法 本试验采用HPLC法测定了18名健康男性受试者口服氨咖黄敏胶囊后不同时刻血浆中对乙酰氨基酚和咖啡因的浓度,用3P97软件拟合房室模型并求出主要药动学参数.结果受试者口服含对乙酰氨基酚750 mg和咖啡因45 mg的氨咖黄敏胶囊制剂后,血浆中对乙酰氨基酚的tmax为(1.03±0.76)h,ρmax为(12.00±3.10)mg·L-1,t1/2为(4.33±1.18)h,用梯形法计算AUC0→t为(52.51±16.81)mg·h·L-1,AUC0→∞为(54.34±17.72)mg·h·L-1;血浆中咖啡因的tmax为(0.89±0.50)h,ρmax为(1.290±0.379)mg·L-1,t1/2为(5.37±2.15)h,用梯形法计算AUC0→t为(7.19±3.03)mg·h·L-1,AUC0-∞为(8.26±3.69)mg·h·L-1.结论 对乙酰氨基酚在人体内符合二房室模型,咖啡因在人体内符合一房室模型.

  5. 牛黄及胆红素对三氯乙烯染毒小鼠脂质过氧化的拮抗作用%The antagonism of cow-bezoar and bilirubin on the lipid peroxidation of mice induced by trichloroethylene

    Institute of Scientific and Technical Information of China (English)

    邰昌松; 赵萍; 黎燕; 杨青; 沈惠麒

    2005-01-01

    目的研究牛黄、胆红素对三氯乙烯(TCE)染毒ICR小鼠所致的脂质过氧化的拮抗作用.方法用TCE灌胃染毒ICR小鼠制造脂质过氧化模型,然后分别以牛黄、胆红素灌胃,测定ICR小鼠肝、肾组织中丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT).结果与阴性对照组比,TCE处理组肝、肾组织GSH-Px、 SOD、CAT活力降低,MDA含量增加,差异均有显著性(P<0.05);牛黄、胆红素染毒与TCE处理组比较,肝、肾组织GSH-Px、 SOD、CAT 活力显著增强(P<0.05),脂质过氧化产物MDA含量减少.结论牛黄和胆红素均能较好地拮抗TCE所引起的ICR小鼠脂质过氧化.

  6. HPLC法测定氨酚咖黄烷胺片中对乙酰氨基酚和咖啡因的含量%Determination of paracetamol and caffeine in paracetamol,caffeine,artificial cow-bezoar and amantadine hydrochloride tablets by HPLC

    Institute of Scientific and Technical Information of China (English)

    孙建平; 张传霞

    2008-01-01

    目的 建立氨酚咖黄烷胺片中对乙酰氨基酚和咖啡因的含量测定方法.方法 采用Hypersil BDS C18色谱柱(150 mm×4.6 mm,5 μm),以甲醇-水(30: 70)为流动相,流速为1.0 ml·min-1,检测波长为270 nm.结果 对乙酰氨基酚在120.06~280.13 mg·L-1范围内线性关系良好,r=0.999 8,平均回收率为99.89%,RSD=0.23%;无水咖啡因在7.24~16.89 mg·L-1范围内线性关系良好,r=0.999 7,平均回收率为99.70%,RSD=0.50%.结论 本法操作简便、准确、快捷,可用于该产品的质量控制.

  7. Content assaying and the uniformity determination of chlorphenamine maleate in child paracetamol, artificial cow-bezoar and chlorphenamine maleate granules%小儿氨酚黄那敏颗粒中马来酸氯苯那敏含量测定及含量均匀度研究

    Institute of Scientific and Technical Information of China (English)

    张丽娥; 诸葛中浙

    2007-01-01

    目的:建立HPLC法测定小儿氨酚黄那敏颗粒中的马来酸氯苯那敏含量的方法并研究其含量均匀度. 方法:采用C18柱,甲醇-0.05 mol/L磷酸二氢钠-三乙胺(300∶700∶0.25),用磷酸调节pH值至2.5为流动相,流速为1mL/min,检测波长为264 nm,进样量为20 μL. 结果:马来酸氯苯那敏的峰面积Y对进样量X(μg)的回归曲线为:Y=7794300X+0.1558;r=0.9996,线性范围为5.56~55.60 μg/mL. 结论:该方法快速简便,重现性好,适用于小儿氨酚黄那敏颗粒中的马来酸氯苯那敏的质量控制.

  8. Determination of paracetamol and caffeine in Paracetamol,Caffeine,Artificial Cow-bezoar and Chlorphenamine Maleate Capsules by HPLC%HPLC法测定氨咖黄敏胶囊中对乙酰氨基酚、咖啡因的含量

    Institute of Scientific and Technical Information of China (English)

    米振清; 彭亚丽; 展霞

    2006-01-01

    目的建立以HPLC法同时测定氨咖黄敏胶囊中对乙酰氨基酚、咖啡因的含量.方法色谱柱C18(250mm),流动相:甲醇-4.2%冰醋酸溶液(3:7),流速:1.0ml·min-1,检测波长为275nm,进样量为20μl.结果对乙酰氨基酚,咖啡因的线性范围分别为25~200μg·ml-1(r=0.9999)、2~12μg·ml-1(r=0.9998),平均回收率分别为99.8%、100.1%.结论本方法简便、快速、准确、专属性高,可用于氨咖黄敏胶囊中对乙酰氨基酚、咖啡因的含量测定.

  9. 高效液相色谱法同时测定氨咖黄敏胶囊中对乙酰氨基酚和马来酸氯苯那敏的含量%Content determination of paracetamol and chlorphenamine maleate in Paracetamol,Caffein,Atificial Cow-bezoar and Chlorphenamine Maleate Capsules by HPLC

    Institute of Scientific and Technical Information of China (English)

    陈玉璞; 张毅; 董智攀

    2010-01-01

    目的:建立高效液相法同时测定氨咖黄敏胶囊中对乙酰氨基酚和马来酸氯苯那敏含量的方法.方法:采用ShimPaok CLC ODS C18(6.0 mm×200 mm,5 μm)色谱柱;流动相:甲醇-0.05 mol/L 磷酸二氢钾溶液-三乙胺(10:90:0.02)(用磷酸调节pH至3.4);检测波长:215 mm;流速:1.0 ml/min;柱温:30℃.结果:对乙酰氨基酚在0.092-4.604μg范围内与峰面积呈良好的线性关系(r=0.9998),平均回收率为98.40%,RSD=I.53%(n=6);马来酸氯苯那敏在4.160-20.800 μg范围内与峰面积呈良好的线性关系(r=0.999 7),平均回收率为99.24%,RSD=1.26%(n=6).结论:本方法简便、准确、重现性好,可用于氨咖黄敏胶囊的质量控制.

  10. 磷酸奥司他韦颗粒联合小儿氨酚黄那敏颗粒治疗小儿季节性流感的效果%Effect of Oseltamivir Phosphate Granules combined with Pediatric Paracetamol Atificial Cow-bezoar and Chlorphenamine Maleate Granules for children with seasonal influenza

    Institute of Scientific and Technical Information of China (English)

    杨立新

    2016-01-01

    目的 探讨磷酸奥司他韦颗粒和小儿氨酚黄那敏颗粒联合治疗对小儿季节性流感的临床效果及安全性.方法 将2015年9~12月航空总医院儿科收治的季节性流感患儿86例作为研究对象,随机分为对照组和观察组,每组各43例.根据患儿的体重给予对照组患儿磷酸奥司他韦颗粒,2次/d,连续服用5d;根据患儿的体重给予观察组患儿不同剂量小儿氨酚黄那敏颗粒,3次/d,连续服用3d,同时联合应用磷酸奥司他韦颗粒,磷酸奥司他韦颗粒的剂量和用法与对照组相同.比较两组患儿的临床有效率、退热时间、咳嗽消失时间、咽痛消失时间、疲倦缓解时间、总症状积分,以及不良反应发生情况.结果 观察组患儿治疗的临床总有效率较对照组明显提高(P<0.05);观察组患儿退热时间、咳嗽消失时间、咽痛消失时间、疲倦缓解时间较对照组明显缩短(P<0.05);观察组患儿治疗后总症状积分明显少于对照组(P<0.05);观察组患儿治疗后肺炎发生率明显低于对照组(P<0.05);治疗前后两组患儿均未出现严重不良反应.结论 磷酸奥司他韦颗粒联合小儿氨酚黄那敏颗粒可明显缓解小儿季节性流感患儿的临床症状,并防止高热惊厥和肺炎的发生,减少并发症的发生,安全性较高,建议推广.

  11. Determination of Paracetamol in Paracetamol, Caffein, Atificial Cow-bezoar and Chlorphenamine Maleate Tablets by UV-spectrophotometry%紫外分光光度法测定氨咖黄敏片中对乙酰氨基酚含量

    Institute of Scientific and Technical Information of China (English)

    文丽丽; 柏学敏; 吕文军

    2005-01-01

    目的:建立测定氨咖黄敏片中对乙酰氨基酚的紫外分光光度法.方法:采用氢氧化钠溶液为溶剂,在257nm波长处测定吸收度,绘制标准曲线.结果:该法测定平均回收率为99.8%,RSD为0.28%,线形范围为4.8~11.2μg/ml,r=0.9999.结论:该分析方法是一种灵敏,准确和简便的分析方法.

  12. Determination of Content and Content Uniformity of Chlorphenamine Maleate in Paracetamol, Caffein, Atificial Cow-Bezoar and Chlorphenamine Maleate Tablets%HPLC法测定氨咖黄敏片中马来酸氯苯那敏的含量及含量均匀度

    Institute of Scientific and Technical Information of China (English)

    吴静芳

    2015-01-01

    目的 建立了HPLC法测定氨咖黄敏片中马来酸氯苯那敏的含量及含量均匀度.方法 采用TSKgel ODS-100V (250mm×4.6 mm,5μm)色谱柱,甲醇-0.05 mol/L磷酸二氢钾溶液(含三乙胺0.03%,用磷酸调pH至3.0) (50:50)为流动相,检测波长为215 nm.结果 马来酸氯苯那敏的线性范围为9.809~29.428 μg/mL(r=0.999 7),平均回收率为100.3%(RSD=0.5%,n=9).结论 本法简单准确,可用于氨咖黄敏片中马来酸氯苯那敏的含量及含量均匀度的测定.

  13. HPLC法测定氨酚咖黄烷胺片中对乙酰氨基酚和咖啡因的含量%Determination of paracetamol and caffeine in Paracetamol, Caffeine, Aritificial Cow-bezoar and Amantadine Hydrochloride Tablets by HPLC

    Institute of Scientific and Technical Information of China (English)

    莫连峰; 陈莹; 唐宁

    2008-01-01

    目的 建立高效液相色谱法测定氨酚咖黄烷胺片中对乙酰氨基酚和咖啡因的含量.方法 采用Kromasil 100AC18柱(250mm×4.6mm,5um),流动相为甲醇-1%冰醋酸(用二乙胺调pH值至3.7)(20:80),检测波长为273nm.结果 对乙酰氨基酚、咖啡因线性范围分别为25~625ug·mL-1,3~75ug·mL-1,平均回收率(n=9)分别为100.6%,99.5%.结论 该方法分离度良好,灵敏度高,准确且简便易行.

  14. Determination of Two Components in Pediatric Paracetamol, Artificial Cow-bezoar and Chlorphenamine Maleate Granules by HPLC and Uniformity of Dosage Units to Chlorphenamine Maleate%HPLC法测定小儿氨酚黄那敏颗粒中二组分的含量及马来酸氯苯那敏含量均匀度考察

    Institute of Scientific and Technical Information of China (English)

    毛威

    2006-01-01

    目的:应用HPLC测定小儿氨酚黄那敏颗粒中对乙酰氨基酚与马来酸氯苯那敏的含量,并对马来酸氯苯那敏的含量均匀度进行考察.方法:采用ODS柱(大连依利特250mm×4.5mm,5μm),以甲醇-0.5mol·ml-1磷酸二氢钠-三乙胺(150:850:0.25),用磷酸调节pH为2.3为流动相,检测波长215nm.结果:平均回收率(n=3)对乙酰氨基酚为99.5%(RSD=0.3%),马来酸氯苯那敏96.8%(RSD=0.4%).结论:该方法快速准确,能更好地控制产品质量.

  15. HPLC-ELSD法测定小儿氨酚黄那敏颗粒中胆酸和猪去氧胆酸的含量%Determination of Cholalic Acid and Hyodeoxycholic Acid in Pediatric Paracetamol, Artificial Cow-bezoar and Chlorphenamine Maleate Granules

    Institute of Scientific and Technical Information of China (English)

    葛玉松

    2015-01-01

    目的:建立以高效液相色谱-蒸发光散射(HPLC-ELSD)检测法测定小儿氨酚黄那敏颗粒中胆酸和猪去氧胆酸含量的方法.方法:采用高效液相色谱法,色谱柱为Capcell Pak MGⅡC18色谱柱(150 mm×4.6 mm,5μm),流动相:甲醇-1%冰醋酸溶液(70∶ 30),检测器为蒸发光散射检测器,漂移管温度为90℃,空气流速为1.8L·min-1.结果:胆酸和猪去氧胆酸分别在进样量0.870~17.392 μg和1.189~ 23.784 μg范围内与峰面积的自然对数呈良好的线性关系,胆酸平均加样回收率为99.8%,RSD=1.5%(n=9);猪去氧胆酸平均加样回收率为100.6%,RSD=1.6% (n =9).结论:本法简便可靠,适用于小儿氨酚黄那敏颗粒的质量控制.

  16. Evaluation of measurement uncertainty for determination of paracetamol and caffeine in Paracetamol,Caffeine,Artificial Cow-bezoar and Chlorphenamine Maleate Capsules%氨咖黄敏胶囊中对乙酰氨基酚、咖啡因含量的测量不确定度评定

    Institute of Scientific and Technical Information of China (English)

    范剑; 米振清

    2009-01-01

    目的:对高效液相色谱法(HPLC)测定氨咖黄敏胶囊中对乙酰氨基酚、咖啡因含量的测量不确定度进行评定.方法:建立HPLC同时测定氨咖黄敏胶囊中对乙酰氨基酚、咖啡因含量的方法,通过对测试方法流程进行分析,确定不确定度来源.结果:结合HPLC方法验证数据,计算合成不确定度及扩展不确定度.结论:通过不确定度评定,对测量过程中产生误差的关键环节有更深刻的认识,有利于进一步提高测量的准确性.

  17. RP-HPLC测定氨咖黄敏胶囊中对乙酰氨基酚及咖啡因的含量%Assay of Paracetamol and Caffeine in Paracetamol, Caffein, Atificial Cow-Bezoar and Chlorphenamine Maleate Capsules by RP-HPLC

    Institute of Scientific and Technical Information of China (English)

    郑虹; 郑永彪; 姜世贤

    2005-01-01

    @@ 氨咖黄敏胶囊为解热镇痛药,常用于伤风感冒等诸多症状.处方中含对乙酰氨基酚、咖啡因、马来酸氯苯那敏、人工牛黄以及适量的辅料,成份较为复杂,已被国家药品标准收载.国家标准[1]中分别采用不同的方法测定对乙酰氨基酚和咖啡因的含量,操作繁琐,费时,误差来源多.本文采用HPLC法,对两种主要组分同时进行分离与检测,该法具有快捷,灵敏,分离度好等优点.

  18. Simultaneous Determination of 4 Synthetic Colors in Child Paracetamol, Artificial Cow-bezoar and Chlorphena Mine Maleate Granules by SPE-HPLC%SPE-HPLC测定小儿氨酚黄那敏颗粒中4种合成色素

    Institute of Scientific and Technical Information of China (English)

    张西如; 赵江丽; 姜建国; 韩彬

    2013-01-01

    目的 建立小儿氨酚黄那敏颗粒剂中合成色素的SPE-HPLC测定方法.方法 使用SPE固相萃取柱对合成着色剂进行净化、富集;采用HPLC测定含量.色谱柱为Inertsil ODS-3 C18柱(4.6 mm×250 mm,5μm);以甲醇-0.02 mol·L-1乙酸铵溶液为流动相,梯度洗脱;检测波长为各自的最大吸收波长(柠檬黄428nm,日落黄521 nm,胭脂红509 nm,苋菜红483 nm);柱温30℃;进样量10 μL;流速1.0 mL·min-1.结果 柠檬黄、日落黄、苋菜红和胭脂红在0.05~4 μg·mL-1内呈良好线性关系(r≥0.999 5),平均回收率分别为98.0%,97.9%,98.6%和99.5%,RSD均<0.9%.结论 该法操作简便、准确、重复性好,可用于同时测定小儿氨酚黄那敏颗粒中的4中合成色素.

  19. HPLC法测定小儿氨酚黄那敏颗粒中马来酸氯苯那敏和对乙酰氨基酚的含量%Determination of Chlorphenamine Maleate and Paracetamol in Pediatric Paracetamol,Artificial Cow-bezoar and Chlorphenamine Maleate Granules by HPLC

    Institute of Scientific and Technical Information of China (English)

    陈杰; 杨小莹; 蒋林波; 于学珍

    2007-01-01

    目的:建立HPLC法测定小儿氨酚黄那敏颗粒中马来酸氯苯那敏和对乙酰氨基酚的含量.方法:采用C18色谱柱(150 mm×4.6 mm,5 μm),以甲醇-0.05 mol/L磷酸二氢钾溶液-三乙胺(10∶90∶0.02)(用磷酸调节pH至4.0)为流动相,柱温为室温,流速为1.0 mL/min,检测波长为215 nm,进样量为20 μL.结果:线性范围分别为马来酸氯苯那敏6.09~14.21 μg/mL,r=0.9999,对乙酰氨基酚17.94~41.86 μg/mL,r=0.9999;平均回收率均为99.14%(n=3).结论:此法快速、准确,可作为本品质量评价和生产工艺监控的有效方法.

  20. HPLC determination of paracetamol and caffein in paracetamol, caffein,atificial cow- bezoar and chlorphenamine maleate capsules and Tablets%HPLC法测定氨咖黄敏胶囊及其片中对乙酰氨基酚和咖啡因的含量

    Institute of Scientific and Technical Information of China (English)

    隆旭红; 金文丽; 刘燕君

    2006-01-01

    目的:建立同时测定氨咖黄敏胶囊(片)中对乙酰氨基酚和咖啡因含量的HPLC法.方法:采用Hypersil C1s(4.6 mm×150 mm,5μm)色谱柱(大连依利特),流动相为1%醋酸溶液(用二乙胺调节pH值至3.7)-甲醇(62∶38),流速为0.8 mL·min-1,检测波长为272 nm,柱温为室温.结果:对乙酰氨基酚在50.0~500.0μg·mL-1范围内具有良好的线性关系,r=0.9996,方法的回收率为99.5%~100.1%,RSD为0.26%~0.30%(n=3);咖啡因在3.0~30.0μg·mL-1范围内具有良好的线性关系,r=0.9997,方法的回收率为99.4%~99.7%,为0.45%~0.60%(n=3).结论:本法简便、准确、灵敏度高,重现性好,可用于氨咖黄敏胶囊(片)中对乙酰氨基酚和咖啡因的含量测定.

  1. Clinical Study of Treatment of Cerebral Coma by Intravenous Drip of Naloxone and Intragastric Administration of Angong Neuhuang Wan (Bezoar Bolus for Resurrection)%静滴纳洛酮及胃内注入安宫牛黄丸治疗脑性昏迷的临床探讨

    Institute of Scientific and Technical Information of China (English)

    黄影柳

    2004-01-01

    目的观察分析静滴纳洛酮及胃内注入安宫牛黄丸对脑性昏迷的治疗效果.方法对44例脑性昏迷病人均予静滴纳洛酮6~8 mg/d,胃内注入安宫牛黄丸2丸/日,予入院时,24小时、72小时、及1周应用Glasgow-Pittsburgh评分,预后采用GOS国际评分.结果治疗组入院时,24小时、72小时,1周G-P评分优于对照组,差异显著,且恢复良好有差异,死亡率减低.结论静滴纳洛酮及胃内注入安宫牛黄丸抢救脑性昏迷有显著疗效,降低致残率及死亡率.

  2. 不同厂家小儿氨酚黄那敏颗粒剂及片剂分剂量的评价%Evaluation of Dose Splitting of Pediatric Paracetamol, Artificial Cow-bezoar and Chlorphenamine Maleate Granules and Tablets Manufactured by Different Pharmaceutical Factories

    Institute of Scientific and Technical Information of China (English)

    缪经纬; 刘元江; 邓欣

    2012-01-01

    目的:评价不同厂家小儿氨酚黄那敏颗粒剂及片剂分剂量的合理性,为提高临床用药水平提供依据.方法:比较11个厂家的小儿氨酚黄那敏颗粒剂及3个厂家的片剂分剂量成丰袋(半片)理论装量(重量)与实际装量(重量)有无显著性差异、不同操作者实际装量(重量)有无显著性差异及半袋实际装量(重量)准确性.结果:A厂的小儿氨酚黄那敏颗粒荆流动性最佳,分剂量成丰袋后,半袋理论装量与半袋实际装量无显著性差异(P>0.05),不同人员操作半袋实际装量无显著性差异(P>0.05),且准确性良好.结论:A厂的小儿氨酚黄那敏颗粒剂适合分半服用.

  3. Intestinal Radiation-Induced Stricture Favours Small Bowel Obstruction by Phytobezoar: Report of a Case

    Directory of Open Access Journals (Sweden)

    Alessandra Quercioli

    2009-01-01

    Full Text Available Bezoars represent the fifth most frequent cause of acute small bowel obstruction. Phytobezoar is the most common type of bezoar. It is a concretion of undigestible fibers derived from ingested vegetables and fruits. We report a case of a woman with a 1-year history of recurrent epigastric and periumbilical abdominal pain with intermittent vomiting caused by phytobezoar of the terminal ileum. After careful investigation of the case and review of literature, we identified the factor involved in bezoar formation as radiation-induced ileal stenosis due to previous treatment for a pelvic tumour. This report provides evidence to consider phytobezoar as a possible cause of small bowel obstruction in patients previously treated with abdominal radiotherapy.

  4. [Occlusion of the gastric outlet caused by a trichobezoar].

    Science.gov (United States)

    Cavuşoğlu, Z; Olcay, E; Dağoğlu, T; Akgün, E; Vural, S; Ateş, R

    1990-10-01

    Bezoars are concretions formed in the gastrointestinal tract. The trichobezoars are hairballs in the stomach or intestines composed of hair. They are usually found in young girls as in our case which we operated in April 1989 on Surgical Ward in Kartal State Hospital in Istanbul. The postgastrectomy state predisposes to bezoar formation. Persimmon peels or pits, orange or grapefruit pulp are the usual offenders. Bezoars are associated with vague upper gastrointestinal discomfort, nausea, and vomiting. The patients may complain of abdominal pain. Ulceration, bleeding, obstruction, and perforation are the most common complications. Treatment consist of mechanical fragmentation via the endoscope or operative extraction. Dissolution of the undigested bolus by ingestion of proteolytic enzymes such as papain may be tried. As prophylaxis the postgastrectomy patient must be warned of ingesting citrus fruits.

  5. Huge gastric diospyrobezoars successfully treated by oral intake and endoscopic injection of Coca-Cola.

    Science.gov (United States)

    Chung, Y W; Han, D S; Park, Y K; Son, B K; Paik, C H; Jeon, Y C; Sohn, J H

    2006-07-01

    A diospyrobezoar is a type of phytobezoar that is considered to be harder than any other types of phytobezoars. Here, we describe a new treatment modality, which effectively and easily disrupted huge gastric diospyrobezoars. A 41-year-old man with a history of diabetes mellitus was admitted with lower abdominal pain and vomiting. Upper gastrointestinal endoscopy revealed three huge, round diospyrobezoars in the stomach. He was made to drink two cans of Coca-Cola every 6 h. At endoscopy the next day, the bezoars were partially dissolved and turned to be softened. We performed direct endoscopic injection of Coca-Cola into each bezoar. At repeated endoscopy the next day, the bezoars were completely dissolved.

  6. 小儿胃肠道植物粪石%Phytobezoars in Infants and Children

    Institute of Scientific and Technical Information of China (English)

    董毓珍; 张金哲; 罗明

    1991-01-01

    93 children with phytobezoars in Beijing Children's Hospital in the past 33 years were reported.77 cases of them were studied.26 of them were gastric bezoars and 51 intestinal bezoars All of them were boys of 7 years or younger,most of them were admittded in late Autumn.All the gastric bezoar patients had a history of eating a lot of unriped Chinese black date(persimmon group).All patients had anorexia,epigastric pain and vomiting.A big movable cake-like mass can always be palpable in tue epigastrum.However patient's general condition remained good.Only one case with gastric bleeding and peritoneal irritation was treated by surgical removal,all the rest were cured by external manual breaking and oral traditional herbs.Intestinal bezoars usually present as a subaeute or chronic intestinal obstruction characterized by abdominal pain,distension,vomiting and a later intoxication and dehydrvtion.42 of 51 cares with oomplete obstruction underwent laparotomy.Among them,bezoars were treated by extra-intestinal breaking and milking downward into the colonin 32.by open-bowel removal in 9.Resection was Performed in a case of the Meckel's diverticulum and intestinal bezoar.For the others,8 cares of incomplete intestinal obstruction were cured with oral liquid paraffin and traditional herbs.Only one case was cured by extra-abdominaI breaking under epidural anesthesia without surgery.The average hospitalization was 6.1 days.There was no death no recurrance except one complicated by wound infection.%本文对77例小儿胃肠道植物粪石的临床症状、诊断、治疗等进行了回顾性分析,并对今后如何早期诊断及预防本病提出了意见.

  7. A giant trichobezoar causing rapunzel syndrome in a 12-year-old female

    Directory of Open Access Journals (Sweden)

    Nadeem Ul Nazeer Kawoosa

    2011-01-01

    Full Text Available Bezoar is a tightly packed collection of undigested material that is unable to exit the stomach. Most bezoars are of indigestible organic matter such as hair-trichobezoars; or vegetable and fruit-phytobezoars; or a combination of both. Trichobezoars commonly occur in patients with psychiatric disturbances who chew and swallow their own hair. In very rare cases, the Rapunzel syndrome hair extends through the pylorus into the small bowel causing symptom and sign of partial or complete gastric outlet obstruction. A case report of trichobezoar in the stomach causing Rapunzel syndrome in a 12-year-old female is reported.

  8. Phytobezoar impaction in a Meckel’s diverticulum; a rare cause of bowel obstruction: Case report and review of literature

    Directory of Open Access Journals (Sweden)

    Bassem Abou Hussein

    2017-01-01

    Conclusion: Complicated Meckel’s diverticulum can have different clinical presentations and can cause bowel obstruction. An association with bezoars impaction is possible and it should be suspected in adult patients presenting with bowel obstruction of unknown causes especially those with high vegetarian diet.

  9. Lactobezoar and cows' milk protein intolerance.

    Science.gov (United States)

    Lemoh, J N; Watt, J

    1980-02-01

    A baby girl of an atopic family who developed eczema, asthma, and cows' milk protein intolerance was found to have a gastric lactobezoar at age 9 1/2 months. She responded well to the removal of the bezoar and to the appropriate dietary treatment.

  10. Rapunzel Syndrome: a rare cause of acute small bowel obstruction

    Directory of Open Access Journals (Sweden)

    Dr. Vipul D Yagnik

    2010-07-01

    Full Text Available The Rapunzel syndrome is a very rare condition where trichobezoar has extended up to the small bowel. Here we are reporting a rare case of Rapunzel syndrome in an adolescent girl with history of trichophagia who presented with small bowel obstruction. Patient underwent exploratory laparotomy and bezoar was removed through gastrotomy. Post-operative course was unremarkable.

  11. How good is cola for dissolution of gastric phytobezoars?

    Institute of Scientific and Technical Information of China (English)

    Beom Jae Lee; Jong-Jae Park; Hoon Jai Chun; Ji Hoon Kim; Jong Eun Yeon; Yoon Tae Jeen; Jae Seon Kim; Kwan Soo Byun; Sang Woo Lee; Jae Hyun Choi; Chang Duck Kim; Ho Sang Ryu; Young-Tae Bak

    2009-01-01

    AIM: To evaluate the efficacy of cola treatment for gastric phytobezoars, including diospyrobezoars. METHODS: A total of 17 patients (range: 48 to 78 years) with symptomatic gastric phytobezoars treated with cola and adjuvant endoscopic therapy were reviewed. Three liters of cola lavage (10 cases) or drink (7 cases) were initially used, and then endoscopic fragmentation was done for the remnant bezoars by using a lithotripsy basket or a polypectomy snare. The overall success of dissolving a gastric phytobezoars with using three liters of cola and the clinical and endoscopic findings were compared retrospectively between four cases of complete dissolution by using only cola and 13 cases of partial dissolution with cola. RESULTS: After 3 L of cola lavage or drinking, a complete dissolution of bezoars was achieved in four patients (23.5%), while 13 cases (76.5%) were only partially dissolved. Phytobezoars (4 of 6 cases) were observed more frequently than diospyrobezoars (0 of 11) in the group that underwent complete dissolution ( P = 0.006). Gender, symptom duration, size of bezoar and method of cola administration were not significantly different between the two groups. Twelve of 13 patients with residual bezoars were completely treated with a combination of cola and endoscopic fragmentation. CONCLUSION: The rate of complete dissolution with three liters of cola was 23.5%, but no case of diospyrobezoar was completely dissolved using this method. However, pretreatment with cola may be helpful and facilitate endoscopic fragmentation of gastric phytobezoars.

  12. Doença de Crohn e farmacobezoar intestinal: relato de caso Crohn's disease and bowel pharmacobezoar: case report

    Directory of Open Access Journals (Sweden)

    Adriana Santos Neves Trece

    2010-06-01

    Full Text Available Bezoares são concreções de materiais diversos, parcialmente ou não digeridos, que podem ser encontrados em qualquer porção do tubo digestivo. Raramente são compostos por fármacos, nestes casos denominados farmacobezoares. Este artigo visa relatar o caso de um paciente com Doença de Crohn complicada por fístula entero-cutânea e áreas de estenoses no íleo terminal apresentando bezoar de mesalazina. Foi enfatizado o caráter multifatorial da gênese dos farmacobezoares, assim como a variada gama de apresentações clínicas e exames diagnósticos úteis no esclarecimento dos casos. Devemos ainda salientar a necessidade de individualização do tratamento para melhor eficácia do mesmo.Bezoars are masses composed of foreign material, partially digested or not, found in any portion of the gastrointestinal tract. Rarely bezoars are composed by medication tablets, becoming known as Pharmacobezoars. This article reports a patient with the Crohn's disease complicated by enteric fistulae and stenotic areas in the ileum presenting Mesalazine pharmacobezoars. The author emphasizes the multi-factorial origin of pharmacobezoars, the wide range of clinical presentations and the diagnostic tools useful in these cases. The individualized treatment necessary to obtain the satisfactory clinical results is also highlighted.

  13. Mechanical colonic obstruction secondary to core of the pomegranate

    Directory of Open Access Journals (Sweden)

    Akın Önder

    2011-09-01

    Full Text Available Bezoars are often common in people with mental retardation and psychiatric disease, a condition that requires surgical intervention. Bezoar is retained concretions of ingested plant or animal materials that accumulate within the gastrointestinal tract. They often form in the stomach and can pass into the small intestine and cause obstruction, rarely leads to perforation. Fitobezoar phenomenon is common all over the world, is one of a rare cause of large bowel obstruction. In this study we report a case of colonic obstruction due to accumulation of edible pomegranates seeds. Fourteen-year-old boy admitted with diagnosis of acute abdomen dependind on ileus to the emergency department were operated. Fytobezoar fully obstructing the lumen of the sigmoid colon was found. Bezoar removed and end colostomy was performed. The patient was discharged after surgery without complication. In children, psychiatric patients, and patients with a history of gastrointestinal surgery in cases of intestinal obstruction differential diagnosis should include bezoars. J Clin Exp Invest 2011; 2 (3: 315-318.

  14. Phytobezoar from the stem ("quiote") of the cactus Agave americana: report of case.

    Science.gov (United States)

    Villarreal, R; Martinez, O; Berumen, U

    1985-11-01

    Agave americana is a cactus growing abundantly in Mexico. Its cooked stem ("quiote") yields by mastication a sweet juice which is swallowed, while the fibers ("bagazo") are spit out. That is the way Mexicans are taught to chew quiote since their early childhood, and it accounts for the rarity of bezoars from this origin. One of such cases is reported herein.

  15. LC-MS/MS法研究氨金黄敏颗粒中对乙酰氨基酚、盐酸金刚烷胺和马来酸氯苯那敏的人体药动学及相对生物利用度%Pharmacokinetics and bioavailability of paracetamol,amantadine hydrochloride and chlorphenamine maleate in paracetamol,amantadine hydrochloride,artificial COW-bezoar and chlorphenamine maleate granules in Chinese healthy volunteers by LC-MS/MS method

    Institute of Scientific and Technical Information of China (English)

    徐晓峰; 陈珺; 宋敏; 杭太俊; 杨林; 文爱东

    2008-01-01

    目的:建立准确、灵敏的液相色谱-串联质谱法(LC-MS/MS)同时测定人血浆中的对乙酰氨基酚、盐酸金刚烷胺和马来酸氯苯那敏,并研究健康受试者单剂量口服氨金黄敏颗粒参比和试验制剂后的药动学和相对生物利用度.方法:20名健康男性受试者进行随机双交叉试验,分别单剂量口服2袋氨金黄敏颗粒(每袋含对乙酰氨基酚150mg,盐酸金刚烷胺50mg,人工牛黄10mg,马来酸氯苯那敏2ms)参比制剂和试验制剂.以盐酸克仑特罗为内标,采用ESI正离子选择性反应监测测定对乙酰氨基酚、盐酸金刚烷胺和马来酸氯苯那敏血浆浓度,计算药动学参数及进行上述三成份的生物利用度评价.结果:由AUC0-T估算,试验制剂中对乙酰氨基酚、盐酸金刚烷胺和马来酸氯苯那敏的相对生物利用度(F)分别为(99.6 ±19.8)%,(98.9±16.0)%,(87.8±13.5)%.结论:建立的LC-MS/MS测定法准确、灵敏,结果可靠;统计分析表明氨金黄敏颗粒试验制剂和参比制剂中对乙酰氨基酚、盐酸金刚烷胺和马来酸氯苯那敏的吸收、分布、消除速率与程度均无明显差异.

  16. A case of hyperemesis in bulimia nervosa.

    Science.gov (United States)

    Pedrolli, Carlo; Sacchi, Manuela C; Togni, Michele; Cereda, Emanuele

    2015-05-01

    Bulimia nervosa is an eating disorder defined by recurrent episodes of binge eating followed by compensatory behaviors, primarily self-induced vomiting. Most common complications are due to purge behaviors and are frequently responsible for hospitalization. These include electrolyte disturbances, dehydration, hypovolemia, stomatitis, esophageal diseases, and functional impairment of the colon. However, an obstruction-like syndrome has never been reported. We report the case of a middle-age woman suffering from bulimia nervosa and referring at the emergency department with a 7-day story of hyperemesis responsible for an acute renal failure. During hospitalization, after the most important and common medical causes of hyperemesis were excluded, an upper gastrointestinal endoscopy was performed. The endoscopist reported the presence of an impressive bezoar, which underwent to mechanical fragmentation and biopsy sampling, revealing it was made up exclusively of liquorice wheels. An endoscopy performed few days after showed the complete dissolution of the bezoar, and the patient was discharged without any further gastrointestinal complaint.

  17. Small bowel obstruction due to phytobezoar formation within meckel diverticulum: CT findings

    Energy Technology Data Exchange (ETDEWEB)

    Frazzini, V.I. Jr.; English, W.J.; Bashist, B.; Moore, E. [Columbia Univ. College of Physicians and Surgeons, New York, NY (United States)

    1996-05-01

    Intestinal obstruction due to a phytobezoar within a Meckel diverticulum is exceedingly rare, with only seven reported cases in the surgical literature. The most important precipitating factor is the ingestion of agents high in fiber and cellulose. Small bowel obstruction in all but one case was due to retrograde propagation of the bezoar into the small bowel lumen. We report the clinical and CT findings in such a patient following a vegetarian diet. 14 refs., 2 figs.

  18. Esophageal space-occupying lesion caused by Ascaris lumbricoides

    OpenAIRE

    Zheng,Ping-Ping; Wang, Bing-Yuan; Wang, Fei(Physics Department, Zhengzhou University, Henan, 450001, China); Ao, Ran; Wang, Ying

    2012-01-01

    Ascaris lumbricoides is the largest intestinal nematode parasite of man, which can lead to various complications because of its mobility. As the esophagus is not normal habitat of Ascaris, the report of esophageal ascariasis is rare. An old female presented with dysphagia after an intake of several red bean buns and haw jellies. The barium meal examination revealed a spherical defect in the lower esophagus. Esophageal bezoar or esophageal carcinoma was considered at the beginning. The patient...

  19. Acute intestinal obstruction caused by a persimmon phytobezoar after dissolution therapy with Coca-Cola.

    Science.gov (United States)

    Ha, Seung Soo; Lee, Hyun Suk; Jung, Min Kyu; Jeon, Seong Woo; Cho, Chang Min; Kim, Sung Kook; Choi, Yong Hwan

    2007-12-01

    Bezoars are concretions or hard masses of foreign matter that are found in the gastrointestinal tract. Recent reports have demonstrated the efficacy of Coca-Cola administration for the dissolution of phytobezors. Here we report on a 73-year-old man with a very large gastric persimmon diospyrobezoar, and this caused small intestinal obstruction after partial dissolution with oral and injected Coca-Cola.

  20. The goat domestication process inferred from large-scale mitochondrial DNA analysis of wild and domestic individuals.

    Science.gov (United States)

    Naderi, Saeid; Rezaei, Hamid-Reza; Pompanon, François; Blum, Michael G B; Negrini, Riccardo; Naghash, Hamid-Reza; Balkiz, Ozge; Mashkour, Marjan; Gaggiotti, Oscar E; Ajmone-Marsan, Paolo; Kence, Aykut; Vigne, Jean-Denis; Taberlet, Pierre

    2008-11-18

    The emergence of farming during the Neolithic transition, including the domestication of livestock, was a critical point in the evolution of human kind. The goat (Capra hircus) was one of the first domesticated ungulates. In this study, we compared the genetic diversity of domestic goats to that of the modern representatives of their wild ancestor, the bezoar, by analyzing 473 samples collected over the whole distribution range of the latter species. This partly confirms and significantly clarifies the goat domestication scenario already proposed by archaeological evidence. All of the mitochondrial DNA haplogroups found in current domestic goats have also been found in the bezoar. The geographic distribution of these haplogroups in the wild ancestor allowed the localization of the main domestication centers. We found no haplotype that could have been domesticated in the eastern half of the Iranian Plateau, nor further to the east. A signature of population expansion in bezoars of the C haplogroup suggests an early domestication center on the Central Iranian Plateau (Yazd and Kerman Provinces) and in the Southern Zagros (Fars Province), possibly corresponding to the management of wild flocks. However, the contribution of this center to the current domestic goat population is rather low (1.4%). We also found a second domestication center covering a large area in Eastern Anatolia, and possibly in Northern and Central Zagros. This last domestication center is the likely origin of almost all domestic goats today. This finding is consistent with archaeological data identifying Eastern Anatolia as an important domestication center.

  1. Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.

    Science.gov (United States)

    Qiao, Xue; Ye, Min; Pan, De-lin; Miao, Wen-juan; Xiang, Cheng; Han, Jian; Guo, De-an

    2011-01-01

    Animal biles and gallstones are popularly used in traditional Chinese medicines, and bile acids are their major bioactive constituents. Some of these medicines, like cow-bezoar, are very expensive, and may be adulterated or even replaced by less expensive but similar species. Due to poor ultraviolet absorbance and structural similarity of bile acids, effective technology for species differentiation and quality control of bile-based Chinese medicines is still lacking. In this study, a rapid and reliable method was established for the simultaneous qualitative and quantitative analysis of 18 bile acids, including 6 free steroids (cholic acid, chenodeoxycholic acid, deoxycholic acid, lithocholic acid, hyodeoxycholic acid, and ursodeoxycholic acid) and their corresponding glycine conjugates and taurine conjugates, by using liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS). This method was used to analyze six bile-based Chinese medicines: bear bile, cattle bile, pig bile, snake bile, cow-bezoar, and artificial cow-bezoar. Samples were separated on an Atlantis dC₁₈ column and were eluted with methanol-acetonitrile-water containing ammonium acetate. The mass spectrometer was monitored in the negative electrospray ionization mode. Total ion currents of the samples were compared for species differentiation, and the contents of bile acids were determined by monitoring specific ion pairs in a selected reaction monitoring program. All 18 bile acids showed good linearity (r² > 0.993) in a wide dynamic range of up to 2000-fold, using dehydrocholic acid as the internal standard. Different animal biles could be explicitly distinguished by their major characteristic bile acids: tauroursodeoxycholic acid and taurochenodeoxycholic acid for bear bile, glycocholic acid, cholic acid and taurocholic acid for cattle bile, glycohyodeoxycholic acid and glycochenodeoxycholic acid for pig bile, and taurocholic acid for snake bile. Furthermore, cattle bile, cow-bezoar

  2. A Rare Case of an Early Postoperative Obstructive Ileus in a Young Female Patient due to a Residual Trichobezoar Mass

    Directory of Open Access Journals (Sweden)

    P. Christopoulos

    2016-01-01

    Full Text Available Trichobezoar is a rare cause of small bowel obstruction, whereby a mass forms most commonly in the stomach and duodenum of young females, from ingestion of hair, a condition known as trichophagia. We present a case of recurrent small bowel obstruction due to a residual hair mass that was removed surgically in a young female patient who had a laparotomy and gastrotomy for removal of a large gastric trichobezoar just two weeks prior to the current admission. This case illustrates the importance of a thorough inspection of the whole bowel to ensure that no residual bezoars remain after surgery.

  3. Primarily Proximal Jejunal Stone Causing Enterolith Ileus in a Patient without Evidence of Cholecystoenteric Fistula or Jejunal Diverticulosis.

    Science.gov (United States)

    Abtar, Houssam Khodor; Mneimneh, Mostapha; Hammoud, Mazen M; Zaaroura, Ahmed; Papas, Yasmina S

    2016-01-01

    Stone formation within the intestinal lumen is called enterolith. This stone can encroach into the lumen causing obstruction and surgical emergency. Jejunal obstruction by an enterolith is a very rare entity and often missed preoperatively. To our knowledge, most cases of jejunal obstruction, secondary to stone, were associated with biliary disease (cholecystoenteric fistula), bezoar, jejunal diverticulosis, or foreign body. Hereby we present a rare case report of small bowel obstruction in an elderly man who was diagnosed lately to have primary proximal jejunal obstruction by an enterolith without evidence of a cholecystoenteric fistula or jejunal diverticulosis. This patient underwent laparotomy, enterotomy with stone extraction, and subsequent primary repair of the bowel.

  4. A rare outcome of iron deficiency and pica: Rapunzel syndrome in a 5-year-old child iron deficiency and pica.

    Science.gov (United States)

    Islek, Ali; Sayar, Ersin; Yılmaz, Aygen; Boneval, Cem; Artan, Reha

    2014-02-01

    Bezoar is defined as the accumulation of organic or nonbiological substances inside the gastrointestinal system. Trichobezoars are the most frequently detected ones and are mostly present in patients with neuropsychiatric disorders. The continuance of the trichobezoar tail-shaped extension over the duodenum and jejunum is described in Rapunzel syndrome. Both conditions are rarely reported in children. The present case submitted here is related to a 5-year-old girl referred with an abdominal mass and anemia, diagnosed with Rapunzel syndrome and developing trichobezoar due to iron deficiency and pica.

  5. Síndrome de Rapunzel: reporte de un caso

    Directory of Open Access Journals (Sweden)

    María Aguilar-Arauz

    2003-06-01

    Full Text Available Se reporta el caso de una niña de tres años con pérdida de peso, anemia ferropénica y síntomas digestivos de varios meses de evolución, quien presentó un episodio de dolor y distensión abdominal intenso, que requirió manejo quirúrgico. Se evidenció la presencia de un tricobezoar asociado con un síndrome de Rapunzel. El síndrome de Rapunzel consiste en la formación de una cola de pelo extendida desde estómago hacia intestino, lo que produce un efecto de acordeón en las asas intestinales, que lleva a necrosis isquémica. Los bezoares, son cuerpos extraños en el tracto gastrointestinal, que pueden ocurrir como resultado de la ingesta de objetos o comidas que no atraviesan el píloro, aumentan de tamaño al sumarse fibras y comida no absorbible. El término se origina a partir de badzher del árabe, padzhar del persa y beluzaar del hebreo, que significan antídoto , ya que en culturas antiguas las piedras o sustancias duras que se encontraban en los estómagos o intestinos de los animales se consideraban sagradas, y se decía tenían poderes curativos. Los bezoares se han observado en mujeres con problemas de personalidad o en individuos portadores de desequilibrios psiquiátricos. Usualmente se desarrollan como complicaciones de cirugía gástrica que alteran la función pilórica, o en circunstancias en que disminuyan la motilidad gástrica o disminuyen la acidez del estómago. Se dividen en varias categorías según el material constituyente: fitobezoares, tricobezoares, lactobezoares, bezoares de levaduras, bezoares como secuelas de cirugía gástrica, concreciones de materiales inorgánicos (asfalto, arena, goma, entre otros.

  6. TEMA 16-2014: Síndrome de Obstrucción Intestinal

    OpenAIRE

    Granados Quesada, Ronny; Vargas Carranza, Julia

    2014-01-01

    La obstrucción intestinal es un conjunto de signos y síntomas que se pueden producir por diversas patologías luminales (bezoares, litos), extraluminales (adherencias) o intramurales (enfermedad de Crohn) del tracto gastrointestinal, peritoneales y sistémicas, que dan como problema principal la imposibilidad de canalizar gases y evacuar el contenido intestinal. Ocupa un 20% de las admisiones quirúrgicas agudas y es una de las causas más frecuentes de intervención quirúrgica.

  7. Síndrome de Rapunzel: reporte de un caso

    Directory of Open Access Journals (Sweden)

    María Aguilar-Arauz

    2003-06-01

    Full Text Available Se reporta el caso de una niña de tres años con pérdida de peso, anemia ferropénica y síntomas digestivos de varios meses de evolución, quien presentó un episodio de dolor y distensión abdominal intenso, que requirió manejo quirúrgico. Se evidenció la presencia de un tricobezoar asociado con un síndrome de Rapunzel. El síndrome de Rapunzel consiste en la formación de una cola de pelo extendida desde estómago hacia intestino, lo que produce un efecto de acordeón en las asas intestinales, que lleva a necrosis isquémica. Los bezoares, son cuerpos extraños en el tracto gastrointestinal, que pueden ocurrir como resultado de la ingesta de objetos o comidas que no atraviesan el píloro, aumentan de tamaño al sumarse fibras y comida no absorbible. El término se origina a partir de badzher del árabe, padzhar del persa y beluzaar del hebreo, que significan antídoto , ya que en culturas antiguas las piedras o sustancias duras que se encontraban en los estómagos o intestinos de los animales se consideraban sagradas, y se decía tenían poderes curativos. Los bezoares se han observado en mujeres con problemas de personalidad o en individuos portadores de desequilibrios psiquiátricos. Usualmente se desarrollan como complicaciones de cirugía gástrica que alteran la función pilórica, o en circunstancias en que disminuyan la motilidad gástrica o disminuyen la acidez del estómago. Se dividen en varias categorías según el material constituyente: fitobezoares, tricobezoares, lactobezoares, bezoares de levaduras, bezoares como secuelas de cirugía gástrica, concreciones de materiales inorgánicos (asfalto, arena, goma, entre otros.We report the case of a 3-year-old female who for several months had unespecific digestive symptoms, weigth loss and iron deficiency anaemia. She suffered an acute abdominal pain episode associated with tenderness that required an exploratory laparotomy. A thrichobezoar was found in the stomach which was

  8. Uncommon Presentation of Gastric Trichobezoar: A Case Report

    Directory of Open Access Journals (Sweden)

    Sam ZERAATIAN

    2015-10-01

    Full Text Available Every material that gastrointestinal system cannot digest will make a bezoar. Trichobezoar is the result of hair inges-tion whether self-hair or from others and is not a common disorder in humans. It is a hairball, which mostly has been seen in females at teenage, or adolescence. It usually locates in stomach but in rare conditions, it will pass through the intestine, and make the Rapunzel syndrome. Herein we present a 13-year-old girl suffering from gastric trichobezoar presenting with failure to thrive.

  9. Uncommon Presentation of Gastric Trichobezoar: A Case Report.

    Science.gov (United States)

    Zeraatian, Sam; Ameri, Sara; Tabesh, Hanif; Kamalzadeh, Nazafarin

    2015-07-01

    Every material that gastrointestinal system cannot digest will make a bezoar. Trichobezoar is the result of hair ingestion whether self-hair or from others and is not a common disorder in humans. It is a hairball, which mostly has been seen in females at teenage, or adolescence. It usually locates in stomach but in rare conditions, it will pass through the intestine, and make the Rapunzel syndrome. Herein we present a 13-year-old girl suffering from gastric trichobezoar presenting with failure to thrive.

  10. The Rapunzel syndrome. Report of a case and review of the literature.

    Science.gov (United States)

    Duncan, N D; Aitken, R; Venugopal, S; West, W; Carpenter, R

    1994-06-01

    The Rapunzel Syndrome, a rare manifestation of trichobezoar, occurs when bolus gastrointestinal obstruction is produced by an unusual trichobezoar with a long tail that extends to or beyond the ileocaecal valve. A five-year-old Jamaican girl presented with this abnormality and was found at laparotomy also to have an ileo-ileal intussusception. For the Rapunzel Syndrome, we recommend bezoar extraction at laparotomy via multiple enterotomies. In addition, psychiatric evaluation and therapy is essential due to the commonly associated finding of underlying emotional stress.

  11. Intestinal Obstruction due to Colonic Lithobezoar: A Case Report and a Review of the Literature

    Directory of Open Access Journals (Sweden)

    Metin Şenol

    2013-01-01

    Full Text Available Bezoar is defined as the accumulation of undigested foreign bodies or nutrients in the gastrointestinal tract. These foreign bodies can be hair (trichobezoar, fibers or seeds of vegetables and fruits (phytobezoar, or remnants of milk (lactobezoar and stones (lithobezoar. Lithobezoar, the accumulation of stones in the digestive tract, is commonly seen in stomach. In this paper, a 7-year-old girl with colonic lithobezoar who presented with constipation, abdominal pain, and the history of pica was successfully treated by the extraction of the stones under general anesthesia.

  12. Intestinal obstruction caused by phytobezoar composed of jaboticaba seeds: case report and literature review

    Directory of Open Access Journals (Sweden)

    Rafael Luís Luporini

    2012-09-01

    Full Text Available Bezoar is a cluster of swallowed and undigested material in the gastrointestinal tract which can cause intestinal obstruction. It has multiple subtypes and the phytobezoar (composed of vegetable fiber is the most common. We report a patient admitted with intestinal obstruction caused by impaction of multiples seeds of jaboticaba in the rectum. The treatment included multiple enemas, laxatives and digital maneuvers and it was effective after four days. Only one similar report was found in the literature.Bezoar trata-se de um aglomerado de material deglutido e não digerido no trato gastrointestinal que pode causar quadro de obstrução intestinal. Existem múltiplos subtipos, sendo o mais comum o fitobezoar (composto por fibras vegetais. Foi relatado o caso de uma paciente admitida com quadro de suboclusão intestinal causada por impactação de múltiplos caroços de jabuticaba em reto. O tratamento instituído foi conservador com múltiplos enteroclimas, laxativos e quebra digital, efetivos após quatro dias. Somente um caso semelhante foi encontrado na literatura.

  13. Síndrome de Rapunzel

    Directory of Open Access Journals (Sweden)

    Luis Arce-Víquez

    2007-01-01

    Full Text Available Se reporta el caso de una niña de 12 años con historia de problemas de aprendizaje y tricofagia de 2 años de evolución, hepatoesplenomegalia y anemia ferropénica. Se requirió manejo quirúrgico se encontró un tricobezoar que se extendía a duodeno. El síndrome de Rapunzel consiste en un tricobezoar que se extiende hacia el intestino delgado, su sintomatología usualmente es inespecífica y por lo general su evolución es benigna. Los bezoares gástricos pueden ocurrir en estómagos normales a causa de la ingestión de objetos que no atraviesan el píloro. Actualmente, la mayoría de bezoares ocurren como complicación de cirugía gástrica, donde hay una función alterada del píloro hipoperistalsis y bajas concentraciones de ácido gástrico. El tricobezoar suele se presentarse en mujeres jóvenes, por la ingesta voluntaria y compulsiva de pelos (trigofagia, a menudo refl ejo de un desajuste de la personalidad.

  14. Tricobezoar gástrico: relato de caso e revisão da literatura

    Directory of Open Access Journals (Sweden)

    César Tadeu Spadella

    1998-04-01

    Full Text Available Bezoar é a impactação de material estranho no interior do trato digestivo, originado a partir da ingestão de diversas substâncias, incluindo cabelos ou pêlos, fibras vegetais e outros. No presente estudo relata-se caso de um volumoso tricobezoar gástrico observado em uma adolescente de 16 anos, com queixa de dor e tumoração palpável na região epigástrica, diagnosticado através da endoscopia digestiva alta. Dada às proporções do bezoar, a paciente foi submetida à gastrotomia anterior com retirada de uma massa sólida de cabelos, com 1200 g, a qual moldava todo o estômago, desde o fundo até o piloro. Uma grande úlcera de pressão também foi detectada em região antral, cujas biópsias revelaram- se negativas para neoplasia. Após a alta, sem intercorrências, a paciente foi encaminhada ao Serviço de Neuropsiquiatria para o tratamento da tricofagia e prevenção da recorrência, objetivo final, ao nosso ver, de todo o tratamento.Bezoar is an impaction of swallowed foreign material into the digestive tract. It is formed from several substances included hairs of humans or animals, vegetable matters and others. At present study the authors report a case of a voluminous gastric trichobezoar observed in a 16-yr-old adolescent with abdominal pain and palpated mass in the epigastrium. Trichobezoar was diagnosed throughout fiberoptic gastroscopy and laparotomy was indicated due to exaggerated size of the mass. Anterior gastrotomy was performed and a solid mass of hairs weighting 1200 g was removed. The removed mass occupied the whole stomach from fundus to pylorus. A big pression ulcer was also detected in the antrum. Biopsies of this ulcer showed to be negatives for neoplasy. There were no complications in postoperative recovery. After discharge the patient was referred to the Neuropsychiatric Service for treatment of trichophagia and prevention of recurrence, in our point of view, the main purpose of all treatment.

  15. An Unusual Cause of Duodenal Obstruction: Persimmon Phytobezoar.

    Science.gov (United States)

    Fan, Shengxian; Wang, Jing; Li, Yousheng

    2016-12-01

    Duodenal phytobezoar, an unusual cause of acute duodenal obstruction, is rarely seen. The most common cause of this type of bezoar is persimmon. It frequently arises from underlying gastrointestinal tract pathologies (gastric surgery, etc.). Here, we report the case of a 66-year-old man who had undergone distal gastrectomy with Billroth I reconstruction for gastric cancer and experienced severe epigastric discomfort, abdominal pain, and vomiting for a few days. The abdominal computed tomography scan showed a large-sized mass in the horizontal portion of the duodenum. On following endoscopic examination, a large phytobezoar was revealed in the duodenum. He was treated with endoscopic fragmentation combined with nasogastric Coca-Cola. The patient tolerated the procedure well and resumed a normal oral diet 3 days later.

  16. Quando a esponja apetece… um caso de pica

    OpenAIRE

    Silva, Marta João; Rocha,Felisbela; Rodrigues, Ana Corina; Ribeiro, Maria do Céu; Carvalho, Sónia; Fonseca, Paula; Carvalho, Fernanda; Graça, Maria Teresa

    2014-01-01

    Introdução: Apica define-se como uma perturbação do comportamento alimentar cuja característica essencial é a ingestão persistente de substâncias não nutritivas por um período de pelo menos um mês.Caso Clínico: Criança do sexo masculino de 5 anos de idade com história de ingestão de esponja sintética (forro de cadeiras, colchões, bases de arranjos florais,..) desde há 8 meses. Internado por suspeita de bezoar, devido ao aparecimento de vómitos matinais com pedaços de esponja e abdominalgias, ...

  17. Primarily Proximal Jejunal Stone Causing Enterolith Ileus in a Patient without Evidence of Cholecystoenteric Fistula or Jejunal Diverticulosis

    Directory of Open Access Journals (Sweden)

    Houssam Khodor Abtar

    2016-01-01

    Full Text Available Stone formation within the intestinal lumen is called enterolith. This stone can encroach into the lumen causing obstruction and surgical emergency. Jejunal obstruction by an enterolith is a very rare entity and often missed preoperatively. To our knowledge, most cases of jejunal obstruction, secondary to stone, were associated with biliary disease (cholecystoenteric fistula, bezoar, jejunal diverticulosis, or foreign body. Hereby we present a rare case report of small bowel obstruction in an elderly man who was diagnosed lately to have primary proximal jejunal obstruction by an enterolith without evidence of a cholecystoenteric fistula or jejunal diverticulosis. This patient underwent laparotomy, enterotomy with stone extraction, and subsequent primary repair of the bowel.

  18. Gastric Trichobezoar Causing Intermittent Small Bowel Obstruction: Report of a Case and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Nicole G. Coufal

    2011-01-01

    Full Text Available We report the unusual case of a 45-year-old woman who presented with multiple episodes of small bowel obstruction. Initial exploratory lap-roscopy did not reveal an etiology of the obstruction. Subsequent upper endoscopy identified a non-obstructing gastric trichobezoar which could not be removed endoscopically but was not thought to be responsible for the small bowel obstruction given its location. One week postoperatively, the patient experienced recurrence of small bowel obstruction. Repeat endoscopy disclosed that the trichobezoar was no longer located in the stomach and upon repeat laparotomy was extracted from the mid-jejunum. In the following 8 months, the patient had no further episodes of small bowel obstruction. Consequently, gastric bezoars should be included in the differential diagnosis of recurrent small bowel obstruction.

  19. Trichobezoar – A Rare Cause of Abdominal Mass and Gastric Outlet Obstruction

    Directory of Open Access Journals (Sweden)

    Ana Couceiro

    2016-01-01

    Full Text Available The authors present the clinical case of a 14-year old girl with weight loss, anorexia, epigastric abdominal pain and postprandial vomiting with 5 months duration. There was a background of trichophagia for 2 years without evidence of alopecia or psychiatric history. The physical examination revealed an epigastric mass motionless, stony, with poorly defined limits, painful on palpation and about 7 cm diameter. Abdominal ultrasonography showed thickening of the gastric wall and antrum with gastric distension. The abdominal tomography scan and endoscopic examination revealed the presence of a bulky trichobezoar occupying almost the entire gastric lumen. It was decided to undergo gastrotomy and extraction of the bezoar. The postoperative period was uneventful.

  20. A Rare Cause of Abdominal Mass: Trichobezoar

    Directory of Open Access Journals (Sweden)

    Atakan Comba

    2013-04-01

    Full Text Available Bezoar is a mass that cannot be digested and that is collected in the gastrointestinal system. Being the exact frequency still unknown; it is rare among children. Trichobezoar is especially encountered in young adolescent girls who have psychiatric/neurologic problems. In this report; a fifteen year old girl who has stomachache and vomiting is presented. A mass without pain on palpation was diagnosed as trichobezoar by performing an endoscopy. A mass which weighed 1.5 kilograms and which took the shape of the stomach was removed out of her stomach by laparatomy. On her psychiatric examination; she was diagnosed with mild mental retardation and obsessive compulsive disorder. Trichobezoar should be considered when adolescent girls with psychiatric problems come with gastrointestinal symptoms such as stomachache and vomiting. (The Jo­ur­nal of Cur­rent Pe­di­at­rics 2014;1:51-3

  1. Study on the Mechanism of Compound Mistletoe Fluidextract in Relieving Hypertension

    Institute of Scientific and Technical Information of China (English)

    YE Fang; DU Guang-zhong; CUI Ai-qing; LU Xiao-ting; WANG You-jing

    2009-01-01

    Objective: To observe the effect of Fufang Jisheng Liujin Gao (复文寄生流浸膏 Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD). Methods: The blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of Niuhuang Jiangya Wan (牛黄降压丸 Bezoar Hypertension-relieving Pills). Results: Both single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD. Conclusion: The hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.

  2. Cows-feet soup: a rare cause of recurrent trichobezoar.

    Science.gov (United States)

    Kiernan, Miles Finbar; Kamat, Sachin; Olagbaiye, Femi

    2012-01-01

    A 45-year-old Afro-Caribbean woman attended the emergency department with worsening dysphagia, abdominal distension, abdominal pain, shortness of breath and generalised weakness. She enjoyed preparing and eating cows-feet stew and preferred to cook the meat with the hair and skin intact. On admission she had a severe microcytic anaemia and was malnourished. Abdominal x-ray and CT revealed a large gastric bezoar. At gastrotomy a foul-smelling 2.42 kg mass of hair, leathery skin and altered food were evacuated from the lesser curvature of the stomach. She had undergone the same procedure 8 years earlier to remove a similar trichobezoar. Following psychiatric review it was deemed that the patient had no underlying psychiatric condition and had full insight into why her trichobezoar had re-occurred. She made a good postoperative recovery and stopped eating cows-feet stew.

  3. Abdominal CT findings of delayed postoperative complications

    Energy Technology Data Exchange (ETDEWEB)

    Zissin, R.; Osadchy, A. [Sapir Medical Center, Dept. of Diagnostic Imaging, Kfar Saba (Israel)]. E-mail: zisinrivka@clalit.org.il; Gayer, G. [Assaf Harofe Medical Center, Dept. of Diagnostic Imaging, Zrifin (Israel)

    2007-10-15

    Despite progress in surgical techniques and modern medical treatment, postoperative complications occur not infrequently and vary according to type of surgery, clinical setting, and time elapsed since surgery. In general, they can be divided into early and delayed complications. Delayed postoperative complications can be classified as specific and nonspecific. The common nonspecific delayed complications are incisional hernia and postoperative bowel obstruction. Bowel obstruction can be further categorized as obstruction related to benign or neoplastic etiology, the latter occurring in oncology patients in whom the primary surgery was related to an underlying abdominal neoplasm. Gossypiboma is another, fortunately rare, postoperative complication. Specific complications appear after specific operations and include the following: Splenosis - following splenectomy. Retained gallstones and spilled gallstones - following cholecystectomy, mainly laparoscopic. Dropped appendicolith and stump appendicitis - following appendectomy, mainly laparoscopic. Obturation obstruction by a bezoar - following gastric surgery. Afferent loop syndrome (ALS) - following Bilroth II gastrectomy. (author)

  4. Rapunzel syndrome resulting in gastric perforation.

    Science.gov (United States)

    Parakh, J S; McAvoy, A; Corless, D J

    2016-01-01

    We report the case of an 18-year-old female patient with no past medical history who presented to the emergency department with acute abdominal pain and vomiting on the background of a long history of ingesting hair (trichophagia). Computed tomography revealed pneumoperitoneum and free fluid in keeping with visceral perforation. In addition, a large hair bolus was seen extending in contiguity from the stomach to the jejunum. A laparotomy was performed, revealing an anterior gastric perforation secondary to a 120cm long trichobezoar, which had formed a cast of the entire stomach, duodenum and proximal jejunum. The bezoar was removed and an omental patch repair to the anterior ulcer was performed. The patient made an excellent postoperative recovery and was discharged home with psychiatric follow-up review.

  5. Inheritance of goat coat colors.

    Science.gov (United States)

    Adalsteinsson, S; Sponenberg, D P; Alexieva, S; Russel, A J

    1994-01-01

    Goat color inheritance was evaluated based on color description of 218 kids and their parents (10 sires, 178 dams) from mixed crosses between several goat populations in an experiment on cashmere fiber production. Altogether 10 color patterns were observed. They were postulated to be caused by 10 alleles at the Agouti locus, with the allele for white or tan color being the top dominant allele, and the nine others codominant. The bottom recessive allele, for nonagouti color, was the 11th allele at this locus. The postulated alleles are white or tan (A(wt)), black mask (A(blm)), bezoar (A(bz)), badgerface (A(b)), grey (A(g)), lightbelly (A(lb)), swiss markings (A(sm)), lateral stripes (A(ls)), mahogany (A(mh)), red cheek (A(rc)), and nonagouti (Aa). Two types of eumelanin pigment were observed, black and light brown, the latter being dominant. Recessive brown was not observed.

  6. Nutritional therapy for the management of diabetic gastroparesis: clinical review

    Directory of Open Access Journals (Sweden)

    Sadiya A

    2012-09-01

    Full Text Available Amena SadiyaLifestyle Clinic, Rashid Centre for Diabetes and Research, Ministry of Health, Ajman, United Arab EmiratesAbstract: Diabetic gastroparesis (DGP, or slow emptying of the stomach, is a well-established complication of diabetes mellitus and is typically considered to occur in individuals with long-standing type 1 and type 2 diabetes mellitus. Clinical consequences of DGP include induction of gastrointestinal (GI symptoms (early satiety, abdominal distension, reflux, stomach spasm, postprandial nausea, vomiting, alteration in drug absorption, and destabilization of glycemic control (due to mismatched postprandial glycemic and insulin peaks. Effective nutritional management not only helps in alleviating the symptoms, but also in facilitating better glycemic control. Although there have been no evidence-based guidelines pertaining to the nutrition care process of the DGP, the current dietary recommendations are based on expert opinions or observational studies. The dietary management of gastroparesis needs to be tailored according to the severity of malnutrition and kind of upper GI symptom by changing the volume, consistency, frequency, fiber, fat, and carbohydrates in the meal. Small frequent meals, using more liquid calories, reducing high fat or high fiber, consuming bezoar forming foods, and adjusting meal carbohydrates based on medications or insulin helps in improving the upper GI symptoms and glycemic control. Enteral nutrition can be an option for patients who fail to stabilize their weight loss, or for those who cannot gain weight with oral feedings, while total parenteral nutrition is rarely necessary for the patient with gastroparesis.Keywords: diabetic gastroparesis, delayed gastric emptying, diabetes mellitus, bezoar, GI symptoms, glycemic control

  7. Correlation Analysis of Common Cold Medicine Ingredients Based on Principal Component Analysis%基于主成份分析法的常用抗感冒药成分相关性分析

    Institute of Scientific and Technical Information of China (English)

    汤宏明

    2013-01-01

    本文对常用抗感冒药进行调查统计的基础上,运用主成份分析的方法,对样本的成分进行分类分析。分析结果表明:抗感冒药一般成分主要有主要乙酰胺基酚、盐酸伪麻黄碱、氢溴酸右美沙芬、扑尔敏、盐酸金刚烷胺、人工牛黄、咖啡因。乙酰胺基酚、盐酸伪麻黄碱、氢溴酸右美沙芬为同一类;扑尔敏为一类;盐酸金刚烷胺、人工牛黄、咖啡因也是一类。此结论基本上是正确合理的,对家庭或医生抗感冒药的选择具有一定的指导作用。%In this paper, commonly used anti-cold medicine survey based on the use of principal component analysis, classification analysis of the composition of the sample. Analysis showed that: the general composition of the anti-cold medicine the major acetaminophen, pseudoephedrine hydrochloride, hydrogen bromideacid dextromethorphan, chlorpheniramine, amantadine hydrochloride, artificial bezoar, caffeine. Acetaminophen, pseudoephedrine hydrochloride, hydrobromide right dextromethorphan same class; chlorpheniramine as a class; amantadine hydrochloride artificial bezoar, caffeine, is also a class. This conclusion is basically correct and reasonable, and has a guiding role in the family or doctors the choice of anti-cold medicine.

  8. The factors influencing urinary arsenic excretion and metabolism of workers in steel and iron smelting foundry.

    Science.gov (United States)

    Shuhua, Xi; Qingshan, Sun; Fei, Wang; Shengnan, Liu; Ling, Yan; Lin, Zhang; Yingli, Song; Nan, Yan; Guifan, Sun

    2014-01-01

    In order to evaluate the degree of arsenic (As) exposure and the factors influencing urinary As excretion and metabolism, 192 workers from a steel and iron smelting plant, with different type of work in production such as roller, steel smelting, iron smelting and metallic charge preparation, were recruited. Information about characteristics of each subject was obtained by questionnaire and inorganic As (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA) in urine were determined. The results showed that steel smelters had significantly higher concentrations of DMA and total As (TAs) than rollers and metallic charge preparation workers, and iron and steel smelters had a higher value of primary methylation index and lower proportion of the iAs (iAs%) than rollers and metallic charge preparation workers. In steel smelters, urinary As level exceeded the biological exposure index (BEI) limit for urinary As of 35 μg/l by 65.52%, and higher than metallic charge preparation workers (35.14%). The individuals consumed seafood in recent 3 days had a higher TAs than the individuals without seafood consumption. Multivariate logistic regression analysis showed that different jobs, taken Chinese medicine of bezoar and seafood consumption in recent 3 days were significantly associated with urinary TAs exceeded BEI limit value 35 μg/l. Our results suggest that workers in steel and iron smelting plant had a lower level of As exposure, and seafood consumption and taking Chinese medicine of bezoar also could increase the risk of urinary TAs exceeded BEI limit value.

  9. Análise radiológica das alterações gastrintestinais após cirurgia de Fobi-Capella Radiological evaluation of postoperative gastrointestinal alterations in patients submitted to Fobi-Capella surgery

    Directory of Open Access Journals (Sweden)

    Marina Celli Francisco

    2007-08-01

    Full Text Available OBJETIVO: Estudar os achados radiológicos encontrados na seriografia digestiva alta no pós-operatório tardio de cirurgia de Fobi-Capella. MATERIAIS E MÉTODOS: Estudo radiológico de 41 pacientes realizado seis a nove meses após a cirurgia de Fobi-Capella. RESULTADOS: As alterações encontradas foram hérnia hiatal (17%, refluxo gastroesofágico (19,5% e deslizamento do anel (4,8%. Os achados menos freqüentes foram fístula enterocutânea (2,4%, estenose da anastomose gastrojejunal (2,4%, bezoar (2,4% e não-visualização do anel em decorrência da sua retirada por intolerância (2,4%. As alterações anatômicas da cirurgia foram claramente demonstradas. CONCLUSÃO: O estudo foi capaz de demonstrar as alterações anatômicas e as complicações da cirurgia de Fobi-Capella.OBJECTIVE: The present study was aimed at evaluating radiological findings of delayed postoperative upper gastrointestinal series in patients submitted to Fobi-Capella surgery. MATERIALS AND METHODS: Radiological studies of 41 patients, six to nine months following the surgery. RESULTS: The following pathological alterations have been found: hiatal hernia (17%, gastroesophageal reflux disease (19.5% and sliding of the silastic ring (4.8%. Least frequent findings have been the following: enterocutaneous fistula (2.4%, stenosis of the gastric pouch outlet (2.4%, bezoar (2.4%, and non-visualization of the silastic ring caused by its removal due to patient intolerance (2.4%. Anatomical alterations resulting from the surgery have been clearly demonstrated. CONCLUSION: The present study could demonstrate anatomical alterations and complications resulting from Fobi-Capella surgery.

  10. Imaging Diagnosis of Large Gastric Trichobezoar: A Case Report and Literature Review%超声诊断巨大毛发性胃结石一例及文献复习

    Institute of Scientific and Technical Information of China (English)

    刘莉; 穆靓; 秦民惠; 李莘; 韦爱华; 张阳

    2011-01-01

    Objective: To investigate the imaging manifestations, clinical features and treatment of large gastric trichobezoar. Methods: The clinical data, imaging findings and treatment of large gastric trichobezoar in one case was retrospectively analyzed with literature review. Results: The child, abdominal pain more than half a year, was diagnosed with large gastric trichobezoar by ultrasound scan. A throughout anamnesis revealed a trichotillomania with trichophagia. Surgery was in form of a laparotomy with gastrotomy through which the mass was evacuated after endoscopic technique confirmed. She was discharged with follow-up remained well. Conclusion: There are no significant differences about imaging manifestations and clinical features between large gastric trichobezoar and other gastric bezoars. The ultrasonic inspection may provide important findings. The aim of treatment is to remove the bezoar and prevent recurrence. It is also recommended that these patients should be evaluated and followed up in a psychiatric clinic.%目的:探讨毛发性胃结石的影像表现、临床特点及治疗.方法:回顾性分析1例毛发性胃结石患者的临床资料,结合文献报道,对其影像、临床表现和治疗方法进行探讨.结果:患者为一女性患儿,上腹痛不适半年余,既往有拔毛癖,超声诊断胃巨大毛发性结石,内镜证实后开腹手术,取石成功,随访痊愈.结论:毛发性胃结石与其它胃结石相比,影像表现、临床特点无明显差异,超声检查可提供可靠的诊断提示,治疗需取出结石以消除症状,并注意心理干预,防止复发.

  11. Nutritional therapy for the management of diabetic gastroparesis: clinical review.

    Science.gov (United States)

    Sadiya, Amena

    2012-01-01

    Diabetic gastroparesis (DGP), or slow emptying of the stomach, is a well-established complication of diabetes mellitus and is typically considered to occur in individuals with long-standing type 1 and type 2 diabetes mellitus. Clinical consequences of DGP include induction of gastrointestinal (GI) symptoms (early satiety, abdominal distension, reflux, stomach spasm, postprandial nausea, vomiting), alteration in drug absorption, and destabilization of glycemic control (due to mismatched postprandial glycemic and insulin peaks). Effective nutritional management not only helps in alleviating the symptoms, but also in facilitating better glycemic control. Although there have been no evidence-based guidelines pertaining to the nutrition care process of the DGP, the current dietary recommendations are based on expert opinions or observational studies. The dietary management of gastroparesis needs to be tailored according to the severity of malnutrition and kind of upper GI symptom by changing the volume, consistency, frequency, fiber, fat, and carbohydrates in the meal. Small frequent meals, using more liquid calories, reducing high fat or high fiber, consuming bezoar forming foods, and adjusting meal carbohydrates based on medications or insulin helps in improving the upper GI symptoms and glycemic control. Enteral nutrition can be an option for patients who fail to stabilize their weight loss, or for those who cannot gain weight with oral feedings, while total parenteral nutrition is rarely necessary for the patient with gastroparesis.

  12. Nutritional therapy for the management of diabetic gastroparesis: clinical review

    Science.gov (United States)

    Sadiya, Amena

    2012-01-01

    Diabetic gastroparesis (DGP), or slow emptying of the stomach, is a well-established complication of diabetes mellitus and is typically considered to occur in individuals with long-standing type 1 and type 2 diabetes mellitus. Clinical consequences of DGP include induction of gastrointestinal (GI) symptoms (early satiety, abdominal distension, reflux, stomach spasm, postprandial nausea, vomiting), alteration in drug absorption, and destabilization of glycemic control (due to mismatched postprandial glycemic and insulin peaks). Effective nutritional management not only helps in alleviating the symptoms, but also in facilitating better glycemic control. Although there have been no evidence-based guidelines pertaining to the nutrition care process of the DGP, the current dietary recommendations are based on expert opinions or observational studies. The dietary management of gastroparesis needs to be tailored according to the severity of malnutrition and kind of upper GI symptom by changing the volume, consistency, frequency, fiber, fat, and carbohydrates in the meal. Small frequent meals, using more liquid calories, reducing high fat or high fiber, consuming bezoar forming foods, and adjusting meal carbohydrates based on medications or insulin helps in improving the upper GI symptoms and glycemic control. Enteral nutrition can be an option for patients who fail to stabilize their weight loss, or for those who cannot gain weight with oral feedings, while total parenteral nutrition is rarely necessary for the patient with gastroparesis. PMID:23055757

  13. Esophageal space-occupying lesion caused by Ascaris lumbricoides

    Institute of Scientific and Technical Information of China (English)

    Ping-Ping Zheng; Bing-Yuan Wang; Fei Wang; Ran Ao; Ying Wang

    2012-01-01

    Ascaris lumbricoides is the largest intestinal nematode parasite of man,which can lead to various complications because of its mobility.As the esophagus is not normal habitat of Ascaris,the report of esophageal ascariasis is rare.An old female presented with dysphagia after an intake of several red bean buns and haw jellies.The barium meal examination revealed a spherical defect in the lower esophagus.Esophageal bezoar or esophageal carcinoma was considered at the beginning.The patient fasted,and received fluid replacement treatment as well as some oral drugs such as proton pump inhibitor and sodium bicarbonate.Then upper gastrointestinal endoscopy was done to further confirm the diagnosis and found a live Ascaris lumbricoides in the gastric antrum and two in the duodenal bulb.The conclusive diagnosis was ascariasis.The esophageal space-occupying lesion might be the entangled worm bolus.Anthelmitnic treatment with mebendazole improved patient's clinical manifestations along with normalization of the radiological findings during a 2-wk follow-up.Authors report herein this rare case of Ascaris lumbricoides in the esophagus,emphasizing the importance of awareness of this parasitic infection as it often presents with different and unspecific symptoms.

  14. Esophageal space-occupying lesion caused by Ascaris lumbricoides.

    Science.gov (United States)

    Zheng, Ping-Ping; Wang, Bing-Yuan; Wang, Fei; Ao, Ran; Wang, Ying

    2012-04-07

    Ascaris lumbricoides is the largest intestinal nematode parasite of man, which can lead to various complications because of its mobility. As the esophagus is not normal habitat of Ascaris, the report of esophageal ascariasis is rare. An old female presented with dysphagia after an intake of several red bean buns and haw jellies. The barium meal examination revealed a spherical defect in the lower esophagus. Esophageal bezoar or esophageal carcinoma was considered at the beginning. The patient fasted, and received fluid replacement treatment as well as some oral drugs such as proton pump inhibitor and sodium bicarbonate. Then upper gastrointestinal endoscopy was done to further confirm the diagnosis and found a live Ascaris lumbricoides in the gastric antrum and two in the duodenal bulb. The conclusive diagnosis was ascariasis. The esophageal space-occupying lesion might be the entangled worm bolus. Anthelmitnic treatment with mebendazole improved patient's clinical manifestations along with normalization of the radiological findings during a 2-wk follow-up. Authors report herein this rare case of Ascaris lumbricoides in the esophagus, emphasizing the importance of awareness of this parasitic infection as it often presents with different and unspecific symptoms.

  15. Clinical Observation on Sheng's Black Plaster in the Treatment of Tendon Injury%生氏黑膏药治疗筋伤的临床观察

    Institute of Scientific and Technical Information of China (English)

    生家耀

    2012-01-01

    目的:探讨生氏黑膏药治疗筋伤的临床疗效.方法:196例筋伤患者采用生氏黑膏药(由麝香、牛黄、珍珠、三七、鹿茸、冰片、血竭、鳖甲等90味原料制成)治疗.结果:痊愈162例,好转30例,无效4例,有效率97.95%.结论:生氏黑膏药治疗筋伤的疗效显著.%Objective:To observe clinical effects of Sheng's Black Plaster on the treatment of tendon injury. Methods: 196 patients of tendon injury were treated by the Sheng's Black Plaster( composed of 90 herbs such as Musk, Bezoar,Genuine pearl, Panax notoginseng, Cornua cervi pantotrichum, Malayan camphor, Daemonorops draco, Carapax trionycis and so on). Results: After treatment, 162 cases were healed,30 were improved,4 were ineffective and the effective rate was 97. 95% . Conclusion:The Sheng's Black Plaster has significant curative effects on the treatment of tendon injury.

  16. Gastric necrosis: A late complication of nissen fundoplication

    Institute of Scientific and Technical Information of China (English)

    Javier; Salinas; Tihomir; Georgiev; Juan; Antonio; González-Sánchez; Elena; López-Ruiz; José; Antonio; Rodríguez-Montes

    2014-01-01

    Gastric necrosis is a rare condition because of the rich blood supply and the extensive submucosal vascular network of the stomach. “Gas-bloat” syndrome is a well known Nissen fundoplication postoperative complica-tion. It may cause severe gastric dilatation, but very rarely an ischemic compromise of the organ. Other factors, such as gastric outlet obstruction, may concur to cause an intraluminal pressure enough to blockade venous return and ultimately arterial blood supply and oxygen deliver, leading to ischaemia. We report a case of a 63-year-old women, who presented a total gastric necrosis following laparoscopic Nissen fundoplication and a pyloric phytobezoar which was the trigger event. No preexisting gastric motility disorders were present by the time of surgery, as demonstrated in the preop-erative barium swallow, thus a poor mastication(patient needed no dentures) of a high fiber meal(cabbage) may have been predisposing factors for the develop-ment of a bezoar in an otherwise healthy women at the onset of old age. A total gastrectomy with esophagojejunostomy was performed and patient was discharged home after a 7-d hospital stay with no immediate com-plications. We also discuss some technical aspects of the procedure that might be important to reduce the incidence of this complication.

  17. Management of SAH with traditional Chinese medicine in China.

    Science.gov (United States)

    Wang, Chunxue; Zhao, Xingquan; Mao, Shujing; Wang, Yongjun; Cui, Xiangning; Pu, Yuehua

    2006-06-01

    China lacks large scale authorized epidemiological study results in allusion to subarachnoid hemorrhage (SAH) within recent 15 years since MONICA (multinational monitoring of trends and determinants in cardiovascular disease) study revealed SAH situation in China in 2000. The main cause of SAH in China is aneurysm which takes up 30-50%, while over 90% aneurysm locates at Willis circle. Early surgery for SAH after aneurysm rupture is the dominant procedure to deal with SAH in China. Moreover, calcium antagonists rank the absolute leading position for cerebral vascular spasm (CVS) among medication-based treatment options. However, traditional Chinese medicine such as Salvia miltiorrhiza, Acanthopanax senticosus, Ginkgo biloba, Pueraria lobata, Liguisticum chuanxiong, cow bezoar, Diospyros kaki and Gynostemma pentaphyllum have been proven beneficial in CVS prevention and treatment, while Salvia miltiorrhiza and TCM soup have unique effects on bleeding absorption. In addition, aescine and some TCM soup might relieve strong headache after SAH. In general, TCM integrated with western medicine have shown unique advantages in the current treatment of SAH in China. However, it is a pity that China still lacks larger scale randomized controlled trials and research on SAH treatment focusing on TCM and the related mechanism of TCM on SAH still need to be investigated further.

  18. Clinical practice: Obstructive renal candidiasis in infancy.

    Science.gov (United States)

    Bisht, Veena; Voort, Judith VanDer

    2011-10-01

    Renal candidiasis is an increasingly common condition affecting predominantly premature infants receiving neonatal intensive care or term infants with urogenital tract anomalies. Multiple risk factors are usually present. Although rare, some infants develop an obstructive uropathy due to fungal balls, and this requires prompt detection and intervention to preserve kidney function. The management of obstructive renal bezoars is challenging and not well summarised in the past. This is mainly due to scarce literature confined to case reports or case series only. This review clarifies various definitions used in relation to renal candidiasis and identifies infants particularly at risk of obstruction. Clinical presentation, diagnosis and the role of imaging are discussed. A summary of the recent literature is provided to outline the range of existing treatment options available with published drug dosages and mode of delivery used. No single approach is successful in all cases and clinicians need to be aware of the different options available: apart from adequate urinary drainage and use of systemic +/- local antifungal agents, additional treatment with fibrinolytic agents and/or endoscopic or open surgical removal may be required. A new simplified algorithm for use in management is proposed. We hope this review will help clinicians in their management of patients presenting with this complex and challenging diagnosis.

  19. Trichophagia along with trichobezoar in the absence of trichotillomania

    Directory of Open Access Journals (Sweden)

    Aseem Mehra

    2014-01-01

    Full Text Available Trichobezoars are rarely described in the absence of trichotillomania. In this report we present a case of trichobezoar associated with trichophagia in the absence of trichotillomania. A 16-year-old girl presented to surgery outpatient with complaints of pain in abdomen and vomiting for the last 6 months. Physical examination revealed a 14 × 16 cm firm, tender, mass with smooth surface, irregular margins, which was mobile with respiration. Ultrasound abdomen revealed a bizarre lesion in the right upper and middle abdomen suggestive of gastric bezoars. Upper gastrointestinal endoscopy did not reveal any abnormality in the esophagus and showed a large mobile mass in the stomach. In view of trichobezoar, psychiatry consultation was sought. Exploration of history revealed that the patient was eating hairs and clay since early childhood. As per patient she would eat hairs thrown by others. She would like the taste of hair and had strong persistent desire to eat hair and would go out searching for the same. At times she would also eat clay. However, she denied of pulling her own hairs. Physical examination of scalp and other body parts did not show any evidence of alopecia or pulling of hair/short hair. She was managed surgically and was counseled about the consequences of eating hairs and clays and was encouraged not to eat hair. To conclude our case suggests that patients can have trichobezoar and trichophagia even in the absence of trichotillomania.

  20. Diospyrobezoar as a Cause of Small Bowel Obstruction

    Directory of Open Access Journals (Sweden)

    Andréia Padilha de Toledo

    2012-09-01

    Full Text Available Phytobezoar, a concretion of indigestible fibers derived from ingested vegetables and fruits, is the most common type of bezoar. Diospyrobezoar is a subtype of phytobezoar formed after excessive intake of persimmons (Diospyros kaki. We report the case of a diabetic man with a 5-day history of abdominal pain after massive ingestion of persimmons who developed signs of complicated small bowel obstruction. The patient had a previous history of Billroth II hemigastrectomy associated with truncal vagotomy to treat a chronic duodenal ulcer 14 years earlier. Since intestinal obstruction was suspected, he underwent emergency laparotomy that revealed an ileal obstruction with small bowel perforation and local peritonitis due to a phytobezoar that was impacted 15 cm above the ileocecal valve. After segmental intestinal resection, the patient had a good recovery and was discharged on the 6th postoperative day. This report provides evidence that diospyrobezoar should be considered as a possible cause of small bowel obstruction in patients who have previously undergone gastric surgery.

  1. The MSCT diagnosis of colon multiple diverticulum%结肠多发憩室的 MSCT 诊断

    Institute of Scientific and Technical Information of China (English)

    赵凡玉; 陆建常; 李高忠

    2015-01-01

    Objective To discuss MSCT signs of colon multiple diverticulum in order to improve the accuracy of diagnosis.Meth-ods MSCT signs and clinical data of 30 cases with colon multiple diverticulum of were analyzed retrospectively.Imaging character-istics of colon multiple diverticulum were summarized and comparated with the results of colonoscopic appearance.Results There were 30 cases of colon multiple diverticulum confirmed by colonoscopy,including 1 6 cases in the ascending colon,6 cases the de-scending colon,5 cases the sigmoid colon,1 case transverse colon,2 cases the whole colon,5 cases with diverticulitis.Multiple pro-jecting processes were showed in 1 9 cases(63.3%,1 9/30),lesion diameter were 3.0-10.0 mm,gas or liquid filled in the lesion in 1 1 cases,small bezoar filled in 8 cases and the surrounding fat gaps were fuzzy in 5 cases.There was no any MSCT abnormal sign in 1 1 cases.Conclusion The typical MSCT signs of colon multiple diverticulum are multiple projecting processes,which size is smaller than 1 cm and filled with gas,liquid or small bezoar.The sign of surrounding fat gap fuzzy often means diverticulitis.%目的:总结结肠多发憩室的多层螺旋 CT(MSCT)表现,提高 MSCT 对结肠多发憩室的诊断水平。方法回顾性分析30例经结肠镜证实的结肠多发憩室临床及 CT 资料,总结其 CT 特征并与结肠镜表现相对照。结果30例经内镜证实结肠多发憩室患者中,发生于升结肠16例,降结肠6例,乙状结肠5例,横结肠1例,全结肠2例;5例提示憩室黏膜炎。19例患者 MSCT 表现为多发突出于肠壁小囊袋状突起(阳性率63.3%,19/30),直径约3.0~10.0 mm,多发小囊状突起内单纯含有气体或液体11例,小粪石充填8例;5例病变肠管周围脂肪间隙模糊;11例病变肠管无明显影像学异常。结论结肠多发憩室较为可靠的 MSCT 表现为多发突出于结肠壁外的小囊状突起,内容物可以是气体、液体及小粪石,直径多<1 cm;当

  2. [Visualization for Traditional Quality Management Techniques--Characterization Method for Spikenard of INUBUSHI SEIYAKU Established in the Edo Period].

    Science.gov (United States)

    Ito, Ken; Inubushi, Soichiro; Moriwaki, Takafumi; Matsunaga, Kazuhiro; Takahashi, Kyoko; Ueda, Takahiro; Hashizume, Setsuya; Takemoto, Hiroaki; Kobayashi, Yoshinori; Ota, Tomoe; Nakamura, Seiko; Matsuda, Hisashi

    2015-01-01

    INUBUSHI SEIYAKU, a Japanese pharmaceutical company established in 1807, manufactures KEISHIN-TAN. This is an original drug developed by the company, and consists of 14 exotic natural medicines, spikenard, oriental bezoar, musk, agarwood, etc. It has been used for adjusting the autonomic nervous system and physical conditions. We studied the original methods of the traditional quality management techniques handed down within INUBUSHI SEIYAKU in selecting the appropriate spikenard (Nardostachys chinensis) for medicinal use. Currently, spikenards are mainly used as incense rather than medicine. KEISHIN-TAN is a rare case in that the bulk powder of the spikenards is used for pharmaceutical products in Japan. We examined the morphological characteristics and made an analysis of the component of spikenards selected by traditional methods. The raw material of the spikenards was purchased from the Japanese market, and was classified into two categories-superior, fit for medicinal use and defective, to be discarded-by traditional methods of INUBUSHI SEIYAKU. The methods of the characterization of the spikenard by INUBUSHI SEIYAKU were investigated. As a result, only thick spikenard roots over 2.0 cm in length and approximately 0.5 cm in diameter were found to be used, and the total weight of the superior was only 15% of the raw material. By comparing the weights of hexane extracts and GC-MS analyses, the content of calarene--main sedative compound in spikenards--in the superior material was 2.8 times higher than the raw material and 4.3 times higher than the defective material. The ways to devise how to enhance the pharmacological effects of spikenards may be contained in this method. These results revealed the traditional spikenard selection criteria, and may show the indications of using spikenard or its compounds for medicinal purposes.

  3. Romanian Words of Arabic Origin: Scientific and Technical Vocabulary

    Directory of Open Access Journals (Sweden)

    Georgeta Rata

    2016-10-01

    Full Text Available There are 141 Romanian words of Arabic origin acquired either directly from Arabic or else indirectly by passing from Arabic into other languages and then into Romanian. Most entered one or more of the Romance languages before entering Romanian. To qualify for this list, a word must be reported in etymology dictionaries as having descended from Arabic. Words associated with the Islamic religion are omitted. Archaic and rare words are also omitted. Given the nature of the journal in which the paper is to be published, the author selected for analysis only about 126 terms belonging to the scientific and technical vocabulary: Adobe, alambic, albatros, alcalin, alchimie, alcool, alfalfa, algebră, algoritm, alidadă, alizarină, amalgam, ambră, anil, antimoniu, azimuth, azur, benjoin, bezoar, bor, cafea, calibre, camfor, carat, carciofoi, caric, cârmâz, carob, chimie, cifru, coton, curcuma, cuşcuş, erg, falafel, fanfară, felucă, fenec, gazelă, gerbil, girafă, halva, hamada, humus, iasomie, jar, julep, kaliu, lac, lămâie, lazurit, liliac, lime, marcasit, masicot, mizenă, muson, nadir, natriu, papagal, rachetă, realgar, sabkha, safari, şah, sandarac, şaorma, şerbet, sirop, sodium, şofran, sorbet, spanac, sumac, tabac, tahân, taifun, talc, tamarin(d, tangerină, tar, tară, tarhon, tarif, tasă, ţechin, ton, varan, zahăr, zenith, zero, zircon, etc. Some of them are obsolescent, but a large number are in everyday use and have been so well assimilated into Romanian that they have produced other words through derivation and composition, or they have acquired new meanings.

  4. An 8-year review of barium studies in the diagnosis of gastroparesis

    Energy Technology Data Exchange (ETDEWEB)

    Levin, A.A. [Department of Radiology, Hospital of University of Pennsylvania, Philadelphia, PA (United States); Levine, M.S. [Department of Radiology, Hospital of University of Pennsylvania, Philadelphia, PA (United States)], E-mail: marc.levine@uphs.upenn.edu; Rubesin, S.E.; Laufer, I. [Department of Radiology, Hospital of University of Pennsylvania, Philadelphia, PA (United States)

    2008-04-15

    Aim: To determine the utility of barium studies for diagnosing gastroparesis in patients with nausea, vomiting, or other related symptoms. Materials and methods: Radiology files revealed gastroparesis without gastric outlet obstruction on upper gastrointestinal tract barium studies in 50 patients with nausea, vomiting, and other related symptoms. Original reports and images were reviewed to determine whether gastric peristalsis was decreased/absent and to investigate gastric dilatation, fluid or debris, and delayed emptying of barium. Twenty patients (40%) had nuclear gastric emptying studies. Medical records were reviewed to determine the presentation, treatment, and course. The diagnosis of gastroparesis was considered accurate if patients with gastroparesis on barium studies responded to treatment. Results: Forty-six patients (92%) had predisposing factors for gastroparesis, including narcotics and diabetes. Forty-five patients (90%) presented with nausea or vomiting, and 40 patients (80%) had one or more other symptoms, including bloating, early satiety, postprandial fullness, and abdominal pain. Barium studies revealed decreased gastric peristalsis in 46 (92%) of the 50 patients and absent peristalsis in four (8%); 46 patients (92%) had additional findings, including gastric dilatation in 30 (60%), delayed emptying of barium in 27 (54%), debris in 28 (56%; bezoars in three), and retained fluid in 13 (26%). Thirteen (65%) of 20 patients with nuclear gastric emptying studies had delayed emptying of solids and seven (35%) had normal emptying. Thirty-five (83%) of 42 patients treated for gastroparesis had symptomatic improvement versus two (25%) of eight patients not treated. Conclusion: Patients with nausea, vomiting, or other related symptoms who have gastroparesis without gastric outlet obstruction on barium studies can be treated for this condition on the basis of the clinical and radiographic findings.

  5. SIMPLIFIED LAPAROSCOPIC GASTRIC BYPASS WITH GASTROJEJUNAL LINEAR MECHANICAL ANASTOMOSIS: TECHNICAL ASPECTS

    Science.gov (United States)

    PALERMO, Mariano; SERRA, Edgardo

    2016-01-01

    ABSTRACT Background: Gastric bypass is a restrictive and malabsorptive surgery. The restrictive part consists in the creation of a small gastric pouch. The gastrointestinal bypass serves as the malabsorptive element. Aim: To describe a simplified gastric bypass approach for morbid obese patients, showing our results, and also remarking the importance of this technique for reducing the learning curve. Method: The patient is positioned in a split legs position and carefully strapped to the operating room table, with the surgeon between the patient's legs. Five trocars are inserted after pneumoperitoneum at the umbilicus. Dissection of the esophagogastric angle and lesser curvature is mandatory before the gastric pouch manufacturing. This pouch is done with two blue load staplers. Using a blue load linear stapler inserted only half way into the hole in the pouch is used to perform the gastrojejunal anastomosis and in order to create an anastomosis that is about 2 cm in length. A side-to-side jejunojejunostomy is done with a white load linear stapler. The last step of the gastric bypass consists in the cut of the jejunum between the two anastomosis with a white load linear stapler. Blue test is performed in order to detect leaks. Results: From January 2012 to December 2015, 415 simplified RYGB were performed. Gender: 67% female and 33 % males. Average of BMI 44.7. Mean age was 42 years old. Mean operative time 79 min. 39 % of this sample had T2 diabetes. Regarding complications were observed, one fistula, one gastrojejunal stenosis and one obstruction due to a bezoar. Conclusion: The described technique is a simplified approach in which all the anastomosis are performed in the upper part of the abdomen, allowing the surgeons to be more systematized and avoiding them to make mistakes in the confection of the Roux-en-Y anastomosis. This simplified gastric bypass is a safe and reproducible technique. PMID:27683785

  6. Phase Ⅱ clinical trial of Shixinyatong buccal tablets in the treatment of gastropyretic toothache(pericoronitis)%石辛牙痛口含片治疗胃火牙痛(智齿冠周炎)Ⅱ期临床试验

    Institute of Scientific and Technical Information of China (English)

    吴军正; 李元聪; 胡开进; 卜献春; 温德升; 关素敏

    2009-01-01

    目的:研究石辛牙痛口含片治疗胃火牙痛(智齿冠周炎)的疗效及安全性.方法:随机双盲双模拟平行对照多中心法.纳入符合胃火牙痛(智齿冠周炎)试验组(石辛)、对照组(牛黄)各120 例.就诊当天行常规冠周袋冲洗.石辛组患者含化石辛牙痛口含片0.6 g×2, 4/d,口服牛黄解毒片的赋形剂0.3 g×3, 3/d;牛黄组患者口服牛黄解毒片0.3 g×3, 3/d,含化石辛牙痛口含片的赋形剂,0.6 g×2, 4/d.主症按0、2、4、6 分级计分;次症按0、1、2、3 分级计分.疗程5 d,用SAS 6.12软件统计分析.用药前后进行血、尿、粪常规及肝功、肾功、心电图检查,记录不良事件.结果:石辛组脱落(失访)3 例,牛黄组脱落2 例.受试者脱落率、人口学特征、病情基线组间差别均无统计学意义(P>0.05).第3 天和第5 天时主症、次症积分以及病情总积分均明显下降(P=0.000),其减少值石辛组大于牛黄组(P0.05),实验室检查全部患者治疗前未出现明显异常变化.3 例发生与研究药物有关不良事件,石辛组1 例,为"中度",停药后好转,退出试验.牛黄组2 例,为轻度,未影响试验.结论:石辛牙痛口含片治疗胃火牙痛(智齿冠周炎)疗效优于牛黄解毒片,安全性与牛黄解毒片相似.%Objective: To study the effects and safety of Shixinyatong buccal tablets in the treatment of gastropyretic toothache (perico-ronitis). Methods: Randemized, double-blinded, double-imitated, parallel-controlled and multi-center clinical study was employed. 120 cases of gastropyretic toothache (pericoronitis) was enrolled in the experimental group( SBT group) and another 120 in control group(CBD group). Pericoronal pocket rinsing was performed for each case at the first visit, then the patients in SBT group were treated by Shixin buccal tablets(SBT) , 0. 6 g×2, 4/d and oral adiministration of the vehicle of cow-bezoare detoxicating tablets,0.3 g×3, 3/ d. The patients in CBD group were

  7. The Diagnostic Value of CT in Perforating Appendicitis%CT诊断穿孔性阑尾炎的价值研究

    Institute of Scientific and Technical Information of China (English)

    刘耀基

    2015-01-01

    目的:探讨穿孔性阑尾炎与非穿孔性阑尾炎的CT鉴别诊断价值。方法回顾性分析70例经术后病理证实为急性阑尾炎患者的临床资料,穿孔组与非穿孔组各35例,分析两组CT表现。结果穿孔组阑尾平均直径(13.28±3.59)mm、阑尾腔外粪石、阑尾腔外气体、阑尾周围脓肿、阑尾壁局限性强化缺损、盆腔炎改变、阑尾周围炎(轻-重)、阑尾周围炎(中-重)(8.57%、25.71%、17.14%、54.29%、62.86%、100%、85.71%)明显高于非穿孔组(P<0.05)。结论 CT是诊断穿孔性阑尾炎的一种有效以及快速的诊断方法,具有较高的鉴别与诊断价值。%Objective To evaluate the differential diagnosis value of CT in perforating appendicitis and non-perforating appendicitis. Methods Clinical data of 70 patients with acute appendicitis confirmed by pathology were studied, divided in to perforating appendicitis group and non-perforating gappendicitis group, each group 35 cases, CT ifndings were analyzed. Results The mean diameter of perforating appendicitis group was(13.28±3.59)mm, outer appendiceal lumen bezoar,outer appendiceal lumen gas, periappendiceal abscess,the appendix wall limitations strengthen defects,pelvic inlfammatory change, inlfammation around the appendix(light-weight), inlfammation around the appendix(in-weight)(8.57%, 25.71%, 17.14%, 54.29%, 62.86%, 100%, 85.71%)was signiifcantly higher than that in the non-perforating group(P<0.05). Conclusion CT is an effective and rapid diagnostic method for perforating appendicitis, with high identiifcation and diagnostic value.

  8. Application of oral Gastrografin in gastroenterography in judgment of the opportunity of operation in simple mechanical small bowel obstruction%口服泛影葡胺胃肠造影在判断单纯性机械性小肠梗阻手术时机中的应用

    Institute of Scientific and Technical Information of China (English)

    李昂; 李非; 方育; 曹锋; 李嘉; 刘殿刚; 梁阔; 张钰鹏; 孙家邦

    2012-01-01

    目的 探讨口服泛影葡胺胃肠造影在判断单纯性机械性小肠梗阻(MSBO)手术时机中的作用.方法 回顾分析2009年1月至2010年12月行口服泛影葡胺胃肠造影的单纯性MSBO病例,造影结果阳性者行手术治疗,阴性者行非手术治疗.结果 共117例行口服泛影葡胺造影的单纯性MSBO病例,其中粘连63.2%、肿瘤12.0%、胃石13.7%、内疝(无手术史)3.4%、原因不明7.7%,造影阳性46例,阴性71例,泛影葡胺胃肠造影用于判断单纯性MSBO手术的特异性和敏感性分别为100%和97.3%.结论 口服泛影葡胺胃肠造影可以较为准确判断单纯性MSBO是否需要手术治疗,特别是区分不需要手术治疗的病例.%Objective To investigate the effect of oral gastrografin on gastroenterography in judgment of the opportunity of operation in simple mechanical small bowel obstruction( MSBO ). Methods A retrospective review was conducted in patients with simple MSBO who received oral Gastrografin in gastroenterography from January 2009 to December 2010. If the outcome of gastroenterography was positive, the patients accepted operation, otherwise, nonoperative treatment was carried out. Results There were 117 patients with simple MSBO overall. The cause of MSBO included adhesions ( 63. 2% ), neoplasms ( 12.0% ),bezoar( 13.7% ),internal hernia without history of abdominal operation( 3.4% ),and etiology unknown( 7. 7% ). The outcome of gastroenterography was positive in 46 patients and negative in 71 patients. Specificity and sensitivity of oral Gastrografin in gastroenterography in judgment of operation opportunity was 100% and 97. 3% Respectively. Conclusion Oral Gastrografin in gastroenterography is effective in judgment of the opportunity of operation in simple MSBO,especially in predicting the need for nonoperative treatment.

  9. 名老中医郑伟达应用慈丹胶囊治疗原发性肺癌医案3则%Famous Chinese Medicine Doctor Zheng Weida’s Three Cases of Primary Lung Cancer Treated with Cidan Capsule

    Institute of Scientific and Technical Information of China (English)

    郑东京; 郑东海; 郑伟鸿; 许鑫; 郑伟达

    2015-01-01

    Primary bronchial lung cancer,short for lung cancer,refers to the alveolar carcinoma originated at bronchial mucosa. Based on long -term clinical experience,Professor Zheng Weida summarized that the cancer was mostly caused by the weakness of inner healthy qi and inner accumulation of evil toxin.The pathogenesis of the cancer is the following:stasis evil invading lung;phlegm -dampness accumulation and the weakness of inner healthy qi.The principles of treatment should be resolving stasis and removing toxin,nourishing yin and clearing heat,invigorating spleen and resolving phlegm as well as replenishing qi and tonifying deficiency.Formulated by Zedoray Rhizome,Edible Tulip,Nux Vomica,Cow -Bezoar,Milkvetch Root,Radix Angelicae Sinen-sis and other five materia medicas,Cidan Capsule has the effect of resolving stasis and removing toxin,alleviating edema and dissi-pating mass,replenishing qi and tonifying middle.Professor Zheng made great improvement in treating primary lung cancer by Ci-dan Capsule.This passage summarized his classical cases in treating the cancer and clinical experience of using Cidan Capsule.%原发性支气管肺癌简称为肺癌,是指原发于支气管黏膜的肺泡癌。郑伟达教授经过长期临床实践总结出肺癌多由正气内虚,邪毒内结所致,病机有下列3点:1)瘀毒侵肺;2)痰湿内聚;3)正气内虚。治宜化瘀解毒,养阴清热,健脾化痰,益气补虚。慈丹胶囊组成为莪术,山慈姑、马钱子、牛黄、黄芪、当归等11味药。具有化瘀解毒、散结消肿、益气健脾的疗效。郑教授运用慈丹胶囊治疗原发性肺癌、取得显著疗效。本文提取郑教授诊治原发性肺癌的经典医案,总结郑教授灵活运用慈丹胶囊的临床经验。

  10. Prescription Rules of Huagan Tongluo Fang%化肝通络方组方规律探讨

    Institute of Scientific and Technical Information of China (English)

    李忠意; 田耀洲

    2014-01-01

    Huagan Tongluo Fang, originated from a famous prescription“Lang Qing A Ta” in Tibetan medicine by Pro-fessor TIAN Yao-zhou, has a significant effect on primary biliary cirrhosis in clinic.The prescription fuses traditional Chinese medicine and Tibetan medicine, having a distinct compatibility, with saffron and artificial cow bezoar as the monarch for nourishing liver and dredging collaterals, flying squirrel faeces, India swertia and emblic leafflower fruit as minister for clearing away liver heat and soothing blood to nourish liver, milk-vetch root, nutmeg, dolomiaea root, aq-uilaria wood and liquorice root as assistant and guide for invigorating spleen to regulate qi.This paper systematically ex-plains prescription rules of Huagan Tongluo Fang, modern pharmacology researches and methods for treating liver and analyzes the prescription rules mainly based on clearing heat, eliminating stasis, dredging collaterals and tonifying spleen from the perspective of theory of traditional Chinese medicine and modern pharmacological research to make a conclusion that the core of the prescription is to nourish liver and dredge collaterals, soothe blood to nourish liver, treat liver and spleen together.%化肝通络方是由田耀洲教授化裁藏医治肝名方“郎庆阿塔”而成,在临床上治疗原发性胆汁淤积性肝硬化( PBC)效果显著。处方融合传统中药、藏药,配伍鲜明,以西红花、人工牛黄为君药,化肝通络;以五灵脂、印度獐牙菜、余甘子为臣药,清化肝热、行血养肝;佐使黄芪、肉豆蔻、木香、沉香、甘草等健脾理气。本文从中医理论角度及现代药理学研究出发,对化肝通络方组方理论依据、现代药理学研究、治肝之法等方面进行系统阐述,分析其组方规律,以清热、化瘀、通络、健脾为主线,总结其组方核心为化肝通络,行血养肝,肝脾同治。

  11. A Study on the local thermal changes following herbal acupuncture on D.I.T.I.

    Directory of Open Access Journals (Sweden)

    Tae-han Yook

    2001-02-01

    Full Text Available Objectives : This study was done to observe the effect on the local thermal changes of herbal acupuncture on D.I.T.I.. The objects of this study are as follows; If there are remarkable local thermal changes between pre and post herbal acupuncture therapy on D.I.T.I.or not. If there are those, We examine how long that changes are maintained, what the adequate interval is on herbal acupuncture therapy, and what the reaction in a local or whole body are on that therapy. Materials and Methods : To study the local thermal changes in herbal acupuncture therapy, D.I.T.I. was used. Determination of this analysis periods are pre and post-therapy(1 hour, 24hours, 48hours and 7days later. The study group was divided into three groups(comprised 23 students in oriental medical college, Woosuk University. One was NS(Normal Saline group, another was CF(CARTHAMI SEMEN group and the other was BU(FEL URSI + BEZOAR BOVIS group. The Herbal Acupunture solution was injected 0.2ml divide into 0.05ml at the P'ungmun(B12, P'yesu(B13, Pubun(B41, Paek'o(B42 4 points. Then, in order to analyze the clinical form, we have observed response of 23 students whenever we checked the thermal changes of their after perfoming Results : The results were obtained as follows 1. There is no significant dermatothermal changes at NS group and CF group, but BU group have remarkable changes in 24, 48, 72 hours. 2. From post-therapy 1 hour to 48 hours, there is a significant change(p<0.01 at NS-BU group and CF-BU group, But there is none 7 days later. 3. In the analysis of whole or local body reaction, local pain appears at NS group(22%, CF group(11%, BU group(91%, discomfort reaction appears at CF group(14%, BU group(30%. BU group has feel vertigo(13%, drowsy(70% and pain in action(52%. 4. In the analysis of the duration of physical reaction, BU group is most lately maintained. Conclusions : These results suggest that in the physical reaction of herbal acupuncture solutions, BU solution is

  12. Tósigos y antídotos en la literatura cervantina: Sobre los venenos en la España tardorrenacentista

    Directory of Open Access Journals (Sweden)

    F López-Muñoz

    2011-01-01

    Full Text Available Los textos cervantinos constituyen una interesante fuente para el estudio de la sociedad española tardorrenacentista. Nosotros hemos abordado las obras de Cervantes desde la óptica de la toxicología, analizando el uso de agentes tóxicos y venenosos, fundamentalmente alucinógenos y narcóticos en el ámbito de la práctica de la brujería y hechicería (ungüentos de brujas, filtros de amor, pócimas venenosas, etc., así como las menciones a las hipotéticas sustancias dotadas de acción alexifármaca, como la verbena (Verbena officinalis, el cuerno de unicornio, las piedras bezoares o el castóreo. Las obras cervantinas en las que se hace referencia a estos preparados son las novelas El Quijote, La Galatea, Viaje del Parnaso y cuatro Novelas Ejemplares (La española inglesa, El licenciado Vidriera, El celoso extremeño y El coloquio de los perros, así como en las comedias Pedro de Urdemalas, La entretenida y El laberinto del amor. Entre los agentes tóxicos de origen herbal citados expresamente por Cervantes en el contexto analizado se encuentran el beleño (Hyoscyamus niger / albus, el tabaco (Nicotiana tabacum, la adelfa (Nerium oleander, el tártago (Euphorbia lathyris, el ruibarbo (Rheum officinale, Rumex alpinus y, de forma enmascarada, el opio (Papaver somniferum. En relación con el resto de preparados dotados de actividad tóxica, Cervantes no identifica sus ingredientes, aunque, a tenor de la sintomatología descrita por el autor, podrían ser plantas de la familia de las solanáceas, como el beleño, el solano, la datura, la belladona o la mandrágora. Con respecto a los tóxicos minerales, únicamente hay referencias a los efectos del mercurio o azogue. El Dioscórides comentado por Andrés Laguna pudo ser la fuente técnica utilizada por Cervantes para documentarse en esta materia.

  13. Effects of Shixinyatong buccal tablets against bateria in pericoronal pocket of patients with pericoronitis%石辛牙痛口含片对智齿冠周炎病人冠周盲袋细菌的抑制作用

    Institute of Scientific and Technical Information of China (English)

    吴军正; 杨聚才; 安银东; 李元聪; 胡开进; 卜献春; 关素敏; 温德升

    2011-01-01

    AIM: To study the effects of Shixinyatong buccal tablets(SBT) against bateria in pericoronalpocket of patients with pericoronitis. METHODS: Randomized, double-blinded, double-imitated, parallel-controlled and multi-centered clinical study was employed. One hunered and twenty cases of gastropyretic toothache ( pericoronitis) was enroled in the experimental group (SBT group) and another 120 in control (BBPD group). Pericoronal pocket rinsing was performed for each case at the first visit. Patients in SBT group were treated by SBT, 0.6g x 2, 4/d and oral adiministration of the vehicle of bovine bezoar pill for detoxification ( BBPD), 0.3g x 3, 3/d. Patients in BBPD group were treated by oral adiministration of BBPD, 0.3gx3, 3/d and the vehicle of SBT, 0.6gx2, 4/d, respectively. The bateria in pericoronal pocket of each case were examined and classified by Bergey's standard before and after treatment. RESULTS: In per protocol set (PPS) there were 112 cases in SBT group and 111 in BBPD group. After treatment, the decreacse rates (%) of total bacteria ( CFU/mL) were 59. 05 ± 25. 64 and 59. 67 ± 27. 25( P > 0.05 ) , the clearance rates ( % ) of the total bacteria in pericoronal pocket in SBT and BBPD groups were 75. 89 and 78.37 (P > 0. 05), the decreacse rates (% ) of total anaerobic bacteria ( CFU/mL) were 83. 48 ± 26. 87 and 82.34 ±24.61 ( P >0.05 ) , the decrease rates ( % ) of total facultative anaerobe( CFU/mL) were 41.57 ± 23. 89 and 40.86 ±30.47(P>0.05), respectively. The decrease rates (% ) of 16 identified bacteria (CFU/mL) were not statistically defferent ( P > 0.05 ). CONLUSION: Shixinyatong buccal tablet and bovine bezoar pill for detoxification have similar antiseptic effects against baterira in pericoronal pocket of patients with pericoronitis.%目的:探讨石辛牙痛口含片治疗胃火牙痛(智齿冠周炎)过程中对冠周盲袋细菌的抑制作用.方法:运用随机双盲双模拟平行对照多中心临床试验,纳入符合胃火牙痛(

  14. 并发肠梗阻的小肠憩室病变的CT表现%The CT findings of jejunoileal diverticulitis resulting in bowel obstruction

    Institute of Scientific and Technical Information of China (English)

    耿兴东; 单秀红; 胡慧; 王鹏

    2016-01-01

    目的:评价多层螺旋CT(MSCT)对引起小肠梗阻的小肠憩室病变及相关并发症的诊断价值。方法回顾性分析13例经手术证实引起小肠梗阻的小肠憩室及相关并发症的CT表现,并与20例未并发梗阻的小肠憩室进行对比分析。结果13例并发肠梗阻患者中,憩室发生于空肠8例,回肠5例。CT表现梗阻端管腔呈圆柱状增宽扩张,单纯性憩室炎3例,管腔内充满肠内容物及少许气泡影,憩室炎伴穿孔2例,管腔如增粗阑尾,周围脂肪间隙条索影,憩室炎伴粪石2例,增大管腔内见环形高密度,憩室炎伴肠扭转6例,表现为旋涡状肠系膜及血管伴扩张管腔影。憩室管壁平均厚度为(3.06±0.31)mm,憩室平均体积为(98.98±38.59)cm3,分别与对照组进行统计学分析,2种征象具有统计学意义(P 值分别为0.000和0.000)。结论 MSCT 有助于并发肠梗阻的小肠憩室及相关并发症诊断。%Objective To evaluate the diagnostic value of MSCT in small bowel obstruction and related complications caused by diverticulitis.Methods Clinical data and CT findings of 13 patients with diverticulitis and related complications were reviewed.The imaging findings of diverticulitis were calculated and compared with those in other 20 cases without intestinal obstruction.Results Among the 1 3 cases with diverticulitis,8 occurred in the j ej unum and other 5 in ileum.CT revealed the diverticulitis in all patients as a predominantly cylindrical expansion in communication with the adjacent small bowel.CT showed intraluminal intestinal contents and little air bubbles in 3 cases with simple diverticulitis,thickening of the appendix lumen in 2 cases with perforated diverticulitis, and annular high-density in lumen in 2 cases with diverticulitis and bezoar.CT also showed diverticulitis with volvulus in 6 cases as mesenteric swirling.The average thickness of diverticula were (3.06±0.31)mm,and the average volume of diverticula were (98.98±38.59)cm

  15. Diagnosis of senile multiple colon diverticula with MSCT%老年性结肠多发憩室的 MSCT 诊断

    Institute of Scientific and Technical Information of China (English)

    张永学; 宋燕; 李红

    2015-01-01

    Objective:To discuss the MSCT features of senile colon multiple diverticula,in order to improve the knowledge of the disease entity.Methods:The clinical and MSCT materials of forty patients with senile multiple colon diver-ticula proved by colonoscopy were collected and the CT features were correlated with colonoscopy appearances.Results:Of the 40 patients with senile multiple colon diverticula,the location was ascending colon (21 patients),descending colon (11 patients),sigmoid colon (5 patients),transverse colon (one patient)and all segments of colon (2 patients).Eight patients had diverticulitis.The MSCT features of senile colon multiple diverticula were multiple small sac-like protrusions bulged outside of the bowel wall,with the diameter ranged from 3.0mm to 10.0mm,gas (16 patients),liquid (11 patients)and small bezoar (13 patients)were showed within the small sac-like protrusions.Fuzzy peri-colonal fat space was assessed in 6 patients.Conclusion:The direct MSCT features of senile multiple colon diverticula are multiple small sac-like protrusions with the diameter less than 1cm outside of the colon wall.Associated diverticulitis is suggested when peri-colonal fuzzy fatty inter-space is showed.%目的:分析老年性结肠多发憩室的多层螺旋 CT 表现,提高对老年性结肠多发憩室认识。方法:搜集40例结肠镜证实的老年性结肠多发憩室临床及 CT 资料,总结 MSCT 特征并与结肠镜表现相对照。结果:40例老年性结肠多发憩室患者中,发生于升结肠的21例,降结肠11例,乙状结肠5例,横结肠1例,全结肠2例。8例提示憩室黏膜炎。老年性结肠多发憩室的 MSCT 表现为多发、突出于肠壁轮廓外的小囊袋状突起,直径3.0~10.0 mm,小囊袋状突起内容物为气体16例,液体11例,粪石13例;6例病变肠管周围脂肪间隙模糊。结论:老年性结肠多发憩室多层螺旋 CT 直接征象为多发、突出于肠轮廓外的囊

  16. 小儿咳嗽的中医临床治疗效果观察%Clinical treatment of children with cough in traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    王锦

    2016-01-01

    Objective To study and analyze the TCM clinical treatment of infantile cough.Methods From March 2014 to Augst 2015 in our hospital for treatment of 84 cases of chronic cough were included in the study, according to the different treatment of the 84 patients were divided into TCM treatment group (n=42) and Western Medicine group (n=42). The Chinese medicine treatment group, using traditional Chinese medicine therapy, drug selection of infantile Feirekechuan oral liquid for the treatment of Western medicine group, with Ambroxol Hydrochloride Oral Solution, Bromhexine Hydrochloride Tablets, Compound Codeine Phosphate Solution, Compound Pholcodine Oral Solution, budesonide, salbutamol sulfate aerosol (Wan Tuolin), Pediatric Paracetamol Atificial Cow-bezoar and Chlorphenamine Maleate Granules. Pediatric Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide Drops and other treatment, compared two groups of children with cough, expectoration, changes in breathing.Results TCM treatment group in cough, sputum, wheezing, improve the situation, better than western medicine treatment group, the above data were significant difference (P < 0.05), the difference is statistically significant.Conclusion The author thinks that, for children with cough, symptomatic treatment can obtain ideal curative effect, in this regard, Chinese medicine treatment method is superior to the traditional western medicine therapy and the treatment measures worthy of a wide range of promotion and use in clinical.%目的:研究并分析小儿咳嗽的中医临床治疗方式。方法:将2014年3月~2015年8月在我院接受治疗的84例慢性咳嗽患儿纳入到本研究,按照治疗方式的不同将84例患儿分为中医治疗组(n=42)与西医治疗组(n=42),对于中医治疗组,采用中药疗法,药物选择小儿肺热咳喘口服液,对于西医治疗组,采用盐酸氨溴索口服液、盐酸溴已新片、复方磷酸可待因溶液、复

  17. 中西医结合治疗小儿烧伤后惊厥的临床疗效观察%Therapeutic Effect of Combination of Traditional Chinese Medicine and West Medicine for Convulsion after Burn Injury in Children

    Institute of Scientific and Technical Information of China (English)

    孟凡勇

    2014-01-01

    Objective To investigate the therapeutic effect of the combination of traditional Chinese medicine( TCM) and west medicine for convulsion after burn injury in children. Methods 96 children with convulsion after burn injury,admitted to our hospital from January 2005 to December 2013,were randomly divided into control group and observation group with each group 48 cases. The control group was given west medicine treatment,including opening air passages,oxygen uptake,sedation, relieving convulsion and abatement of fever. While the observation group was given additional drip-feed of Qingkailing Injection, oral Bezoar Bolus,oral and packed Zixue Pellet.χ2 was used to compare the therapeutic effect of the two groups. Results After treatment,32 cases were significantly improved,14 cases were improved and 2 cases were invalid in the observation group,with a total therapeutic effect of 95. 8%;26 cases were significantly improved,8 cases were improved and 14 cases were invalid in the control group,with a total therapeutic effect of 70. 8%,which was significantly higher than the control group(χ2 =11. 56, P<0. 05). Conclusion The therapeutic effect is fairly good by combining TCM and west medicine,which is conducive to the childrenˊs immediate rehabilitation.%目的:观察中西医结合治疗小儿烧伤后惊厥的临床疗效。方法选取2005年1月-2013年12月本院烧伤科收治的烧伤后惊厥患儿96例,将其随机分为对照组和观察组,各48例。对照组患儿给予西医治疗,包括通畅呼吸道、吸氧、镇静、止痉、退热等常规治疗。观察组在对照组治疗的基础上,另给予清开灵注射液静脉滴注,安宫牛黄丸口服,紫雪丹口服、外敷。采用χ2检验比较两组患儿治疗后的总有效率。结果治疗后观察组显效32例,有效14例,无效2例,总有效率为95.8%;对照组显效26例,有效8例,无效14例,总有效率为70.8%。观察组患儿总

  18. In-line monitoring of blending process of Zhongsheng pill powder using miniature near-infrared analyzer%微型近红外仪用于众生丸粉末混合过程的在线监测研究

    Institute of Scientific and Technical Information of China (English)

    金叶; 杨凯; 陈木洲; 刘雪松; 陈勇; 龙超峰; 吴永江

    2011-01-01

    Objective; To establish a simple and rapid method baaed on diffuse reflectance NIR spectra to in-line monitor the blending process of Zhongsheng pill powder. Method; Zhongsheng pill powder consisted of Zhongsheng spray powder, artificial cow-bezoar powder and bile arisaema powder. By means of a revolutionary miniature near-infrared analyzer mounted onto the blender, the powder homogeneity van determined in real lime with noninterference. The moving hlnck standard deviation ( MBSD) method was used to identify the end point of blending process, providing real-time data and instant feedback about the blending course. Evaluation of blend uniformity was carried out by stratified in-process sampling, and the content of baicalin in samples was determined by high performance liquid chromatngraphy (HPLC). Result; The results calculated through MBSD method were generally coincided with HPLC analysis. Blend homogeneity was assumed to be reached when the standard deviations beiween spectra approached 0.002, and RSD values of baicalin content in samplesfrom six positions were lower than 5%. Moreover, stratified in-process sampling has significant influence on blending process when the powder loading volume was small. Conclusion^ Based on this study, NIR speetroscopy can be possibly extended to be applied in blending process of Zliongsheng pill powder, ensuring a remarkable saving of time and manpower employed and creating.a reliable and efficient process measurement technology.%目的:建立一种众生丸粉末混合过程终点的在线判断方法.方法:将微型近红外仪直接安装于混合罐进料口上,通过移动窗标准偏差法(MBSD)在线监测混合过程中混合物的均匀度变化,实时判断混合终点.同时采用取样探针分层抽样,通过液相色谱法分析粉末样品中黄芩苷含量,用于验证MBSD的终点判断结果.结果:近红外在线监测结果与液相测定结果基本一致,当光谱偏差小于0.002时,不同取样