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Sample records for beta-electron transfer flavoprotein

  1. Late-onset form of beta-electron transfer flavoprotein deficiency

    DEFF Research Database (Denmark)

    Curcoy, A; Olsen, Rikke Katrine Jentoft; Ribes, A;

    2003-01-01

    Multiple acyl-CoA-dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) are a group of metabolic disorders due to deficiency of either electron transfer flavoprotein (ETF) or electron transfer flavoprotein ubiquinone oxidoreductase (ETF-QO). We report the clinical features...... and biochemical and molecular genetic analyses of a patient with a mild late-onset form of GAII due to beta-ETF deficiency. Biochemical data showed an abnormal urine organic acid profile, low levels of free carnitine, increased levels of C(10:1n-6), and C(14:1n-9) in plasma, and decreased oxidation of [9,10-3H......]palmitate and [9,10-3H]myristate in fibroblasts, suggesting MAD deficiency. In agreement with these findings, mutational analysis of the ETF/ETFDH genes demonstrated an ETFB missense mutation 124T>C in exon 2 leading to replacement of cysteine-42 with arginine (C42R), and a 604_606AAG deletion in exon 6...

  2. Electron transfer flavoprotein deficiency: Functional and molecular aspects

    DEFF Research Database (Denmark)

    Schiff, M; Froissart, R; Olsen, Rikke Katrine Jentoft;

    2006-01-01

    Multiple acyl-CoA dehydrogenase deficiency (MADD) is a recessively inherited metabolic disorder that can be due to a deficiency of electron transfer flavoprotein (ETF) or its dehydrogenase (ETF-ubiquinone oxidoreductase). ETF is a mitochondrial matrix protein consisting of alpha- (30kDa) and beta...

  3. Late-onset form of beta-electron transfer flavoprotein deficiency

    DEFF Research Database (Denmark)

    Curcoy, A; Olsen, R K J; Ribes, A;

    2003-01-01

    and biochemical and molecular genetic analyses of a patient with a mild late-onset form of GAII due to beta-ETF deficiency. Biochemical data showed an abnormal urine organic acid profile, low levels of free carnitine, increased levels of C(10:1n-6), and C(14:1n-9) in plasma, and decreased oxidation of [9,10-3H...... in the ETFB gene resulting in the deletion of lysine-202 (K202del). The present report delineates further the phenotype of mild beta-ETF deficiency and illustrates that the differential diagnosis of GAII is readily achieved by mutational analysis....

  4. The electron transfer flavoprotein fixABCX gene products from Azospirillum brasilense show a NifA-dependent promoter regulation.

    Science.gov (United States)

    Sperotto, Raul Antonio; Gross, Jeferson; Vedoy, Cleber; Passaglia, Luciane Maria Pereira; Schrank, Irene Silveira

    2004-10-01

    The complete nucleotide sequence of the A. brasilense fixA, fixB, fixC, and fixX genes is reported here. Sequence similarities between the protein sequences deduced from fixABCX genes and many electron transfer flavoproteins (ETFs) have been noted. Comparison of the amino acid sequences of both subunits of ETF with the A. brasilense fixA and fixB gene products exhibits an identity of 30%. The amino acid sequence of the other two genes, fixC and fixX, revealed similarity with the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase (ETF-QO). Using site-directed mutagenesis, mutations were introduced in the fixA promoter element of the A. brasilense fixABCX operon and chimeric p fixA-lacZ reporter gene fusions were constructed. The activation of the fixA promoter of A. brasilense is dependent upon the presence of the NifA protein being approximately 7 times less active than the A. brasilense nifH promoter. These results indicate that NifA from Klebsiella pneumoniae activates the fix promoter of A. brasilense and provide further evidence in support of the regulatory model of NifA activation in A. brasilense. Although no specific function has been assigned to the fixABCX gene products they are apparently required for symbiotic nitrogen fixation. An electron-transferring capacity in the nitrogen fixation pathway has been suggested for the fix gene products based on sequence homologies to the ETFs and ETF-QO proteins and by the absence of orthologous electron transfer proteins NifJ and NifF in A. brasilense.

  5. Human METTL20 Methylates Lysine Residues Adjacent to the Recognition Loop of the Electron Transfer Flavoprotein in Mitochondria*

    Science.gov (United States)

    Rhein, Virginie F.; Carroll, Joe; He, Jiuya; Ding, Shujing; Fearnley, Ian M.; Walker, John E.

    2014-01-01

    In mammalian mitochondria, protein methylation is a relatively uncommon post-transcriptional modification, and the extent of the mitochondrial protein methylome, the modifying methyltransferases, and their substrates have been little studied. As shown here, the β-subunit of the electron transfer flavoprotein (ETF) is one such methylated protein. The ETF is a heterodimer of α- and β-subunits. Lysine residues 199 and 202 of mature ETFβ are almost completely trimethylated in bovine heart mitochondria, whereas ETFα is not methylated. The enzyme responsible for the modifications was identified as methyltransferase-like protein 20 (METTL20). In human 143B cells, the methylation of ETFβ is less extensive and is diminished further by suppression of METTL20. Tagged METTL20 expressed in HEK293T cells specifically associates with the ETF and promotes the trimethylation of ETFβ lysine residues 199 and 202. ETF serves as a mobile electron carrier linking dehydrogenases involved in fatty acid oxidation and one-carbon metabolism to the membrane-associated ubiquinone pool. The methylated residues in ETFβ are immediately adjacent to a protein loop that recognizes and binds to the dehydrogenases. Suppression of trimethylation of ETFβ in mouse C2C12 cells oxidizing palmitate as an energy source reduced the consumption of oxygen by the cells. These experiments suggest that the oxidation of fatty acids in mitochondria and the passage of electrons via the ETF may be controlled by modulating the protein-protein interactions between the reduced dehydrogenases and the β-subunit of the ETF by trimethylation of lysine residues. METTL20 is the first lysine methyltransferase to be found to be associated with mitochondria. PMID:25023281

  6. Flavoproteins, iron proteins, and hemoproteins as electron-transfer components of the sulfate-reducing bacteria

    Energy Technology Data Exchange (ETDEWEB)

    LeGall, J. (Centre National de la Recherche Scientifique, Marseille, France); DerVartanian, D.V.; Peck, H.D. Jr.

    1979-01-01

    This review article with 105 references discusses the most recent publications that deal with the discovery of new redox proteins of the sulfate-reducing bacteria belonging to the genera Desulfotomaculum and Desulfovibrio and proposes explanations for their physical and biological functions. The redox proteins studied as part of the electron-transfer system of these bacteria include flavodoxins, ferredoxins, rubredoxins, cytochromes and several reductose-type enzymes. (KRM)

  7. Functional characterization of electron-transferring flavoprotein and its dehydrogenase required for fungal development and plant infection by the rice blast fungus.

    Science.gov (United States)

    Li, Ya; Zhu, Jindong; Hu, Jiexiong; Meng, Xiuli; Zhang, Qi; Zhu, Kunpeng; Chen, Xiaomin; Chen, Xuehang; Li, Guangpu; Wang, Zonghua; Lu, Guodong

    2016-01-01

    Electron-transferring flavoprotein (ETF) and its dehydrogenase (ETFDH) are highly conserved electron carriers which mainly function in mitochondrial fatty acid β oxidation. Here, we report the identification and characterization of ETF α and β subunit encoding genes (ETFA and ETFB) and ETFDH encoding gene (ETFDH) in the rice blast fungus Magnaporthe oryzae. It was demonstrated that, by impacting fatty acid metabolism, ETF and ETFDH mutations led to severe growth and conidiation defects, which could be largely rescued by exogenous acetate or carbonate. Furthermore, although conidium germination and appressorium formation appeared to be normal in ETF and ETFDH mutants, most appressoria failed to penetrate the host epidermis due to low turgor pressure. The few appressoria that succeeded in penetration were severely restricted in invasive growth and consequently failed to cause disease. Moreover, ETF mutant etfb(-) induced ROS accumulation in infected host cells and exogenous antioxidant GSH accelerated mutant invading growth without increasing the penetration rate. In addition, mutant etfb(-) displayed elevated lipid body accumulation and reduced ATP synthesis. Taken together, ETF and ETFDH play an important role in fungal development and plant infection in M. oryzae by regulation of fatty acid metabolism, turgor establishment and induction of host ROS accumulation. PMID:27113712

  8. The growing VAO flavoprotein family

    NARCIS (Netherlands)

    Leferink, Nicole G. H.; Heuts, Dominic P. H. M.; Fraaije, Marco W.; van Berkel, Willem J. H.

    2008-01-01

    The VAO flavoprotein family is a rapidly growing family of oxidoreductases that favor the covalent binding of the FAD cofactor. In this review we report on the catalytic properties of some newly discovered VAO family members and their mode of flavin binding. Covalent binding of the flavin is a self-

  9. cDNA cloning, functional expression and cellular localization of rat liver mitochondrial electron-transfer flavoprotein-ubiquinone oxidoreductase protein

    Institute of Scientific and Technical Information of China (English)

    HUANG; Shengbing; SONG; Wei; LIN; Qishui

    2005-01-01

    A membrane-bound protein was purified from rat liver mitochondria. After being digested with V8 protease, two peptides containing identical 14 amino acid residue sequences were obtained. Using the 14 amino acid peptide derived DNA sequence as gene specific primer, the cDNA of correspondent gene 5'-terminal and 3'-terminal were obtained by RACE technique. The full-length cDNA that encoded a protein of 616 amino acids was thus cloned, which included the above mentioned peptide sequence. The full length cDNA was highly homologous to that of human ETF-QO, indicating that it may be the cDNA of rat ETF-QO. ETF-QO is an iron sulfur protein located in mitochondria inner membrane containing two kinds of redox center: FAD and [4Fe-4S] center. After comparing the sequence from the cDNA of the 616 amino acids protein with that of the mature protein of rat liver mitochondria, it was found that the N terminal 32 amino acid residues did not exist in the mature protein, indicating that the cDNA was that of ETF-Qop. When the cDNA was expressed in Saccharomyces cerevisiae with inducible vectors, the protein product was enriched in mitochondrial fraction and exhibited electron transfer activity (NBT reductase activity) of ETF-QO. Results demonstrated that the 32 amino acid peptide was a mitochondrial targeting peptide, and both FAD and iron-sulfur cluster were inserted properly into the expressed ETF-QO. ETF-QO had a high level expression in rat heart, liver and kidney. The fusion protein of GFP-ETF-QO co-localized with mitochondria in COS-7 cells.

  10. Flavoproteins: Studies on flavodoxins and phenol hydroxylase.

    NARCIS (Netherlands)

    Peelen, J.C.J.

    1996-01-01

    Flavoproteins play an important role in a variety of catalytic reactions. The chemistry underlying these reactions is quite different from case to case. The basis for this broad reaction spectrum is formed by the flavin. Free flavin is a versatile molecule, capable to undergo many different chemical

  11. Turning a monocovalent flavoprotein into a bicovalent flavoprotein by structure-inspired mutagenesis

    NARCIS (Netherlands)

    Kopacz, Malgorzata M.; Fraaije, Marco W.

    2014-01-01

    A recently discovered class of bicovalent flavoproteins is an interesting group of enzymes because of their unusual cofactor binding mode, their open active sites and the bulky substrates they can accept. Through a sequence comparison study we have identified a conserved sequence region in bicovalen

  12. Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis

    Directory of Open Access Journals (Sweden)

    Teresa Anna eGiancaspero

    2015-04-01

    Full Text Available The primary role of the water-soluble vitamin B2 (riboflavin in cell biology is connected with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases, oxidases and reductases involved in energetic metabolism, epigenetics, protein folding, as well as in a number of diverse regulatory processes. The problem of localisation of flavin cofactor synthesis events and in particular of the FAD synthase (EC 2.7.7.2 in HepG2 cells is addressed here by confocal microscopy in the frame of its relationships with kinetics of FAD synthesis and delivery to client apo-flavoproteins. FAD synthesis catalysed by recombinant isoform 2 of FADS occurs via an ordered bi-bi mechanism in which ATP binds prior to FMN, and pyrophosphate is released before FAD. Spectrophotometric continuous assays of the reconstitution rate of apo-D-aminoacid oxidase with its cofactor, allowed us to propose that besides its FAD synthesising activity, hFADS is able to operate as a FAD chaperone.The physical interaction between FAD forming enzyme and its clients was further confirmed by dot blot and immunoprecipitation experiments carried out testing as a client either a nuclear or a mitochondrial enzyme that is lysine specific demethylase 1 (LSD1, EC 1.-.-.- and dimethylglycine dehydrogenase (Me2GlyDH, EC 1.5.8.4, respectively which carry out similar reactions of oxidative demethylation, assisted by tetrahydrofolate used to form 5,10-methylene-tetrahydrofolate. A direct transfer of the cofactor from hFADS2 to apo-dimethyl glycine dehydrogenase was also demonstrated. Thus, FAD synthesis and delivery to these enzymes are crucial processes for bioenergetics and nutri-epigenetics of liver cells.

  13. Remaining challenges in cellular flavin cofactor homeostasis and flavoprotein biogenesis

    Science.gov (United States)

    Giancaspero, Teresa Anna; Colella, Matilde; Brizio, Carmen; Difonzo, Graziana; Fiorino, Giuseppina Maria; Leone, Piero; Brandsch, Roderich; Bonomi, Francesco; Iametti, Stefania; Barile, Maria

    2015-04-01

    The primary role of the water-soluble vitamin B2 (riboflavin) in cell biology is connected with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases, oxidases and reductases involved in energetic metabolism, epigenetics, protein folding, as well as in a number of diverse regulatory processes. The problem of localisation of flavin cofactor synthesis events and in particular of the FAD synthase (EC 2.7.7.2) in HepG2 cells is addressed here by confocal microscopy in the frame of its relationships with kinetics of FAD synthesis and delivery to client apo-flavoproteins. FAD synthesis catalysed by recombinant isoform 2 of FADS occurs via an ordered bi-bi mechanism in which ATP binds prior to FMN, and pyrophosphate is released before FAD. Spectrophotometric continuous assays of the reconstitution rate of apo-D-aminoacid oxidase with its cofactor, allowed us to propose that besides its FAD synthesising activity, hFADS is able to operate as a FAD "chaperone". The physical interaction between FAD forming enzyme and its clients was further confirmed by dot blot and immunoprecipitation experiments carried out testing as a client either a nuclear or a mitochondrial enzyme that is lysine specific demethylase 1 (LSD1, EC 1.-.-.-) and dimethylglycine dehydrogenase (Me2GlyDH, EC 1.5.8.4), respectively which carry out similar reactions of oxidative demethylation, assisted by tetrahydrofolate used to form 5,10-methylene-tetrahydrofolate. A direct transfer of the cofactor from hFADS2 to apo-dimethyl glycine dehydrogenase was also demonstrated. Thus, FAD synthesis and delivery to these enzymes are crucial processes for bioenergetics and nutri-epigenetics of liver cells.

  14. The Oxidation of Thiols by Flavoprotein Oxidases : a Biocatalytic Route to Reactive Thiocarbonyls

    NARCIS (Netherlands)

    Ewing, Tom A.; Dijkman, Willem P.; Vervoort, Jacques M.; Fraaije, Marco W.; van Berkel, Willem J. H.

    2014-01-01

    Flavoprotein oxidases are a diverse class of biocatalysts, most of which catalyze the oxidation of C-O, C-N, or C-C bonds. Flavoprotein oxidases that are known to catalyze the oxidation of C-S bonds are rare, being limited to enzymes that catalyze the oxidative cleavage of thioethers. Herein, we rep

  15. The Oxidation of Thiols by Flavoprotein Oxidases: a Biocatalytic Route to Reactive Thiocarbonyls.

    NARCIS (Netherlands)

    Ewing, T.A.; Dijkman, W.P.; Vervoort, J.J.M.; Fraaije, M.W.; Berkel, van W.J.H.

    2014-01-01

    Flavoprotein oxidases are a diverse class of biocatalysts, most of which catalyze the oxidation of C[BOND]O, C[BOND]N, or C[BOND]C bonds. Flavoprotein oxidases that are known to catalyze the oxidation of C[BOND]S bonds are rare, being limited to enzymes that catalyze the oxidative cleavage of thioet

  16. LOV to BLUF: Flavoprotein Contributions to the Optogenetic Toolkit

    Institute of Scientific and Technical Information of China (English)

    John M. Christie; Jayde Gawthorne; Gillian Young; Niall J. Fraser; Andrew J. Roe

    2012-01-01

    Optogenetics is an emerging field that combines optical and genetic approaches to non-invasively interfere with cellular events with exquisite spatiotemporal control.Although it arose originally from neuroscience,optogenetics is widely applicable to the study of many different biological systems and the range of applications arising from this technology continues to increase.Moreover,the repertoire of light-sensitive proteins used for devising new optogenetic tools is rapidly expanding.Light,Oxygen,or Voltage sensing (LOV) and Blue-Light-Utilizing flavin adenine dinucleotide (FAD) (BLUF) domains represent new contributors to the optogenetic toolkit.These small (100-140-amino acids) flavoprotein modules are derived from plant and bacterial photoreceptors that respond to UV-A/blue light.In recent years,considerable progress has been made in uncovering the photoactivation mechanisms of both LOV and BLUF domains.This knowledge has been applied in the design of synthetic photoswitches and fluorescent reporters with applications in cell biology and biotechnology.In this review,we summarize the photochemical properties of LOV and BLUF photosensors and highlight some of the recent advances in how these flavoproteins are being employed to artificially regulate and image a variety of biological processes.

  17. Regulatory mechanism of the flavoprotein Tah18-dependent nitric oxide synthesis and cell death in yeast.

    Science.gov (United States)

    Yoshikawa, Yuki; Nasuno, Ryo; Kawahara, Nobuhiro; Nishimura, Akira; Watanabe, Daisuke; Takagi, Hiroshi

    2016-07-01

    Nitric oxide (NO) is a ubiquitous signaling molecule involved in the regulation of a large number of cellular functions. The regulatory mechanism of NO generation in unicellular eukaryotic yeast cells is poorly understood due to the lack of mammalian and bacterial NO synthase (NOS) orthologues, even though yeast produces NO under oxidative stress conditions. Recently, we reported that the flavoprotein Tah18, which was previously shown to transfer electrons to the iron-sulfur cluster protein Dre2, is involved in NOS-like activity in the yeast Saccharomyces cerevisiae. On the other hand, Tah18 was reported to promote apoptotic cell death after exposure to hydrogen peroxide (H2O2). Here, we showed that NOS-like activity requiring Tah18 induced cell death upon treatment with H2O2. Our experimental results also indicate that Tah18-dependent NO production and cell death are suppressed by enhancement of the interaction between Tah18 and its molecular partner Dre2. Our findings indicate that the Tah18-Dre2 complex regulates cell death as a molecular switch via Tah18-dependent NOS-like activity in response to environmental changes. PMID:27178802

  18. The flavoprotein Tah18-dependent NO synthesis confers high-temperature stress tolerance on yeast cells

    Energy Technology Data Exchange (ETDEWEB)

    Nishimura, Akira; Kawahara, Nobuhiro [Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192 (Japan); Takagi, Hiroshi, E-mail: hiro@bs.naist.jp [Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192 (Japan)

    2013-01-04

    Highlights: Black-Right-Pointing-Pointer NO is produced from L-arginine in response to elevated temperature in yeast. Black-Right-Pointing-Pointer Tah18 was first identified as the yeast protein involved in NO synthesis. Black-Right-Pointing-Pointer Tah18-dependent NO synthesis confers tolerance to high-temperature on yeast cells. -- Abstract: Nitric oxide (NO) is a ubiquitous signaling molecule involved in the regulation of a large number of cellular functions. In the unicellular eukaryote yeast, NO may be involved in stress response pathways, but its role is poorly understood due to the lack of mammalian NO synthase (NOS) orthologues. Previously, we have proposed the oxidative stress-induced L-arginine synthesis and its physiological role under stress conditions in yeast Saccharomyces cerevisiae. Here, our experimental results indicated that increased conversion of L-proline into L-arginine led to NO production in response to elevated temperature. We also showed that the flavoprotein Tah18, which was previously reported to transfer electrons to the Fe-S cluster protein Dre2, was involved in NO synthesis in yeast. Gene knockdown analysis demonstrated that Tah18-dependent NO synthesis confers high-temperature stress tolerance on yeast cells. As it appears that such a unique cell protection mechanism is specific to yeasts and fungi, it represents a promising target for antifungal activity.

  19. Electron donation to the flavoprotein NifL, a redox-sensing transcriptional regulator.

    Science.gov (United States)

    Macheroux, P; Hill, S; Austin, S; Eydmann, T; Jones, T; Kim, S O; Poole, R; Dixon, R

    1998-06-01

    Transcriptional control of the nitrogen fixation (nif) genes in response to oxygen in Azotobacter vinelandii is mediated by nitrogen fixation regulatory protein L (NifL), a regulatory flavoprotein that modulates the activity of the transcriptional activator nitrogen fixation regulatory protein A (NifA). CD spectra of purified NifL indicate that FAD is bound to NifL in an asymmetric environment and the protein is predominantly alpha-helical. The redox potential of NifL is -226 mV at pH 8 as determined by the enzymic reduction of NifL by xanthine oxidase/xanthine in the presence of appropriate mediators. The reduction of NifL by xanthine oxidase prevented NifL from acting as an inhibitor of NifA. In the absence of electron mediators NifL could also be reduced by Escherichia coli flavohaemoprotein (Hmp) with NADH as reductant. Hmp contains a globin-like domain with haem B as prosthetic group and an FAD-containing oxidoreductase module. The carboxyferrohaem form of Hmp was competent to reduce NifL, suggesting that electron donation to NifL originates from the flavin in Hmp rather than by direct electron transfer from the haem. Spinach ferredoxin:NAD(P) oxidoreductase, which adopts a folding similar to the FAD- and NAD-binding domains of Hmp, also reduced NifL with NADH as reductant. Re-oxidation of NifL occurs rapidly in the presence of air, raising the possibility that NifL might sense intracellular oxygen. We propose a physiological redox cycle in which the oxidation of NifL by oxygen and hence the activation of its inhibitory properties occurs rapidly, in contrast with the switch from the active to the reduced form of NifL, which occurs more slowly. PMID:9601070

  20. Azotobacter vinelandii NIFL is a flavoprotein that modulates transcriptional activation of nitrogen-fixation genes via a redox-sensitive switch.

    Science.gov (United States)

    Hill, S; Austin, S; Eydmann, T; Jones, T; Dixon, R

    1996-03-01

    The NIFL regulatory protein controls transcriptional activation of nitrogen fixation (nif) genes in Azotobacter vinelandii by direct interaction with the enhancer binding protein NIFA. Modulation of NIFA activity by NIFL, in vivo occurs in response to external oxygen concentration or the level of fixed nitrogen. Spectral features of purified NIFL and chromatographic analysis indicate that it is a flavoprotein with FAD as the prosthetic group, which undergoes reduction in the presence of sodium dithionite. Under anaerobic conditions, the oxidized form of NIFL inhibits transcriptional activation by NIFA in vitro, and this inhibition is reversed when NIFL is in the reduced form. Hence NIFL is a redox-sensitive regulatory protein and may represent a type of flavoprotein in which electron transfer is not coupled to an obvious catalytic activity. In addition to its ability to act as a redox sensor, the activity of NIFL is also responsive to adenosine nucleotides, particularly ADP. This response overrides the influence of redox status on NIFL and is also observed with refolded NIFL apoprotein, which lacks the flavin moiety. These observations suggest that both energy and redox status are important determinants of nif gene regulation in vivo. PMID:8700899

  1. Iron-Sulfur Flavoprotein (Isf) from Methanosarcina thermophila Is the Prototype of a Widely Distributed Family

    OpenAIRE

    Zhao, Tong; Cruz, Francisco; Ferry, James G.

    2001-01-01

    A total of 35 homologs of the iron-sulfur flavoprotein (Isf) from Methanosarcina thermophila were identified in databases. All three domains were represented, and multiple homologs were present in several species. An unusually compact cysteine motif ligating the 4Fe-4S cluster in Isf is conserved in all of the homologs except two, in which either an aspartate or a histidine has replaced the second cysteine in the motif. A phylogenetic analysis of Isf homologs identified four subgroups, two of...

  2. Impact of ionization of ferrocene: EOES of alpha- and beta- electrons and the fingerprint orbital of ferrocenium

    CERN Document Server

    Wang, Feng

    2015-01-01

    Ionization process of ferrocene (Fc) to produce ferrocenium cation (Fc+) has been debated as much as the eclipsed and staggered ferrocene conformers. The present quantum mechanical study reveals that removal of an electron does not apparently affect the geometry and symmetry of the cation, as the geometric changes are < 2% with respect to neutral Fc, but produce the fingerprint orbital 8a1 of Fc+. The excess orbital energy spectrum (EOES) of the \\alpha- and \\beta-electrons reveals that the electrons originated from the transition metal Fe in both core and valence shells experience significant energy changes in the cation with respect to the neutral ferrocene counterparts, indicating that the Fe-electrons correlate stronger than electrons from other atoms such as carbons in ferrocene. The EOES also exhibits that the orbital energies of the \\alpha-electrons in ferrocenium change more significantly than the \\beta-electrons after one \\beta-electron being ionized with respect to ferrocene. The most significant ...

  3. Binding of the Covalent Flavin Assembly Factor to the Flavoprotein Subunit of Complex II.

    Science.gov (United States)

    Maklashina, Elena; Rajagukguk, Sany; Starbird, Chrystal A; McDonald, W Hayes; Koganitsky, Anna; Eisenbach, Michael; Iverson, Tina M; Cecchini, Gary

    2016-02-01

    Escherichia coli harbors two highly conserved homologs of the essential mitochondrial respiratory complex II (succinate:ubiquinone oxidoreductase). Aerobically the bacterium synthesizes succinate:quinone reductase as part of its respiratory chain, whereas under microaerophilic conditions, the quinol:fumarate reductase can be utilized. All complex II enzymes harbor a covalently bound FAD co-factor that is essential for their ability to oxidize succinate. In eukaryotes and many bacteria, assembly of the covalent flavin linkage is facilitated by a small protein assembly factor, termed SdhE in E. coli. How SdhE assists with formation of the covalent flavin bond and how it binds the flavoprotein subunit of complex II remain unknown. Using photo-cross-linking, we report the interaction site between the flavoprotein of complex II and the SdhE assembly factor. These data indicate that SdhE binds to the flavoprotein between two independently folded domains and that this binding mode likely influences the interdomain orientation. In so doing, SdhE likely orients amino acid residues near the dicarboxylate and FAD binding site, which facilitates formation of the covalent flavin linkage. These studies identify how the conserved SdhE assembly factor and its homologs participate in complex II maturation.

  4. Microbial flavoprotein monooxygenases as mimics of mammalian flavin-containing monooxygenases for the enantioselective preparation of drug metabolites

    NARCIS (Netherlands)

    Gul, Turan; Krzek, Marzena; Permentier, Hjalmar; Fraaije, Marco; Bischoff, Rainer

    2016-01-01

    Mammalian flavin-containing monooxygenases are difficult to obtain and study while they play a major role in detoxifying various xenobiotics. In order to provide alternative biocatalytic tools to generate FMO-derived drug metabolites, a collection of microbial flavoprotein monooxygenases, sequence-r

  5. MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis.

    Science.gov (United States)

    Liu, Qingyang; Liu, Fan; Yu, Ka Lou; Tas, Roderick; Grigoriev, Ilya; Remmelzwaal, Sanne; Serra-Marques, Andrea; Kapitein, Lukas C; Heck, Albert J R; Akhmanova, Anna

    2016-09-23

    During cytokinesis, the antiparallel array of microtubules forming the central spindle organizes the midbody, a structure that anchors the ingressed cleavage furrow and guides the assembly of abscission machinery. Here, we identified a role for the flavoprotein monooxygenase MICAL3, an actin disassembly factor, in organizing midbody-associated protein complexes. By combining cell biological assays with cross-linking mass spectrometry, we show that MICAL3 is recruited to the central spindle and the midbody through a direct interaction with the centralspindlin component MKLP1. Knock-out of MICAL3 leads to an increased frequency of cytokinetic failure and a delayed abscission. In a mechanism independent of its enzymatic activity, MICAL3 targets the adaptor protein ELKS and Rab8A-positive vesicles to the midbody, and the depletion of ELKS and Rab8A also leads to cytokinesis defects. We propose that MICAL3 acts as a midbody-associated scaffold for vesicle targeting, which promotes maturation of the intercellular bridge and abscission. PMID:27528609

  6. Detoxification of Indole by an Indole-Induced Flavoprotein Oxygenase from Acinetobacter baumannii.

    Directory of Open Access Journals (Sweden)

    Guang-Huey Lin

    Full Text Available Indole, a derivative of the amino acid tryptophan, is a toxic signaling molecule, which can inhibit bacterial growth. To overcome indole-induced toxicity, many bacteria have developed enzymatic defense systems to convert indole to non-toxic, water-insoluble indigo. We previously demonstrated that, like other aromatic compound-degrading bacteria, Acinetobacter baumannii can also convert indole to indigo. However, no work has been published investigating this mechanism. Here, we have shown that the growth of wild-type A. baumannii is severely inhibited in the presence of 3.5 mM indole. However, at lower concentrations, growth is stable, implying that the bacteria may be utilizing a survival mechanism to oxidize indole. To this end, we have identified a flavoprotein oxygenase encoded by the iifC gene of A. baumannii. Further, our results suggest that expressing this recombinant oxygenase protein in Escherichia coli can drive indole oxidation to indigo in vitro. Genome analysis shows that the iif operon is exclusively present in the genomes of A. baumannii and Pseudomonas syringae pv. actinidiae. Quantitative PCR and Western blot analysis also indicate that the iif operon is activated by indole through the AraC-like transcriptional regulator IifR. Taken together, these data suggest that this species of bacteria utilizes a novel indole-detoxification mechanism that is modulated by IifC, a protein that appears to be, at least to some extent, regulated by IifR.

  7. Detoxification of Indole by an Indole-Induced Flavoprotein Oxygenase from Acinetobacter baumannii.

    Science.gov (United States)

    Lin, Guang-Huey; Chen, Hao-Ping; Shu, Hung-Yu

    2015-01-01

    Indole, a derivative of the amino acid tryptophan, is a toxic signaling molecule, which can inhibit bacterial growth. To overcome indole-induced toxicity, many bacteria have developed enzymatic defense systems to convert indole to non-toxic, water-insoluble indigo. We previously demonstrated that, like other aromatic compound-degrading bacteria, Acinetobacter baumannii can also convert indole to indigo. However, no work has been published investigating this mechanism. Here, we have shown that the growth of wild-type A. baumannii is severely inhibited in the presence of 3.5 mM indole. However, at lower concentrations, growth is stable, implying that the bacteria may be utilizing a survival mechanism to oxidize indole. To this end, we have identified a flavoprotein oxygenase encoded by the iifC gene of A. baumannii. Further, our results suggest that expressing this recombinant oxygenase protein in Escherichia coli can drive indole oxidation to indigo in vitro. Genome analysis shows that the iif operon is exclusively present in the genomes of A. baumannii and Pseudomonas syringae pv. actinidiae. Quantitative PCR and Western blot analysis also indicate that the iif operon is activated by indole through the AraC-like transcriptional regulator IifR. Taken together, these data suggest that this species of bacteria utilizes a novel indole-detoxification mechanism that is modulated by IifC, a protein that appears to be, at least to some extent, regulated by IifR. PMID:26390211

  8. Transfer

    DEFF Research Database (Denmark)

    Wahlgren, Bjarne; Aarkrog, Vibe

    Bogen er den første samlede indføring i transfer på dansk. Transfer kan anvendes som praksis-filosofikum. Den giver en systematisk indsigt til den studerende, der spørger: Hvordan kan teoretisk viden bruges til at reflektere over handlinger i situationer, der passer til min fremtidige arbejdsplads?...

  9. Motor dysfunction in the tottering mouse is linked to cerebellar spontaneous low frequency oscillations revealed by flavoprotein autofluorescence optical imaging

    Science.gov (United States)

    Chen, Gang; Popa, Laurentiu S.; Wang, Xinming; Gao, Wangcai; Barnes, Justin; Hendrix, Claudia M.; Hess, Ellen J.; Ebner, Timothy J.

    2009-02-01

    Flavoprotein autofluorescence optical imaging is developing into a powerful research tool to study neural activity, particularly in vivo. In this study we used this imaging technique to investigate the neuronal mechanism underlying the episodic movement disorder that is characteristic of the tottering (tg) mouse, a model of episodic ataxia type 2. Both EA2 and the tg mouse are caused by mutations in the gene encoding Cav2.1 (P/Q-type) voltage-gated Ca2+ channels. These mutations result in a reduction in P/Q Ca2+ channel function. Both EA2 patients and tg mice have a characteristic phenotype consisting of transient motor attacks triggered by stress, caffeine or ethanol. The neural events underlying these episodes of dystonia are unknown. Flavoprotein autofluorescence optical imaging revealed spontaneous, transient, low frequency oscillations in the cerebellar cortex of the tg mouse. Lasting from 30 - 120 minutes, the oscillations originate in one area then spread to surrounding regions over 30 - 60 minutes. The oscillations are reduced by removing extracellular Ca2+ and blocking Cav 1.2/1.3 (L-type) Ca2+ channels. The oscillations are not affected by blocking AMPA receptors or by electrical stimulation of the parallel fiber - Purkinje cell circuit, suggesting the oscillations are generated intrinsically in the cerebellar cortex. Conversely, L-type Ca2+ agonists generate oscillations with similar properties. In the awake tg mouse, transcranial flavoprotein imaging revealed low frequency oscillations that are accentuated during caffeine induced attacks of dystonia. The oscillations increase during the attacks of dystonia and are coupled to oscillations in face and hindlimb EMG activity. These transient oscillations and the associated cerebellar dysfunction provide a novel mechanism by which an ion channel disorder results in episodic motor dysfunction.

  10. Azotobacter vinelandii NIFL is a flavoprotein that modulates transcriptional activation of nitrogen-fixation genes via a redox-sensitive switch.

    OpenAIRE

    Hill, S.; Austin, S; Eydmann, T.; Jones, T.; Dixon, R

    1996-01-01

    The NIFL regulatory protein controls transcriptional activation of nitrogen fixation (nif) genes in Azotobacter vinelandii by direct interaction with the enhancer binding protein NIFA. Modulation of NIFA activity by NIFL, in vivo occurs in response to external oxygen concentration or the level of fixed nitrogen. Spectral features of purified NIFL and chromatographic analysis indicate that it is a flavoprotein with FAD as the prosthetic group, which undergoes reduction in the presence of sodiu...

  11. Nucleotide sequence of the fixABC region of Azorhizobium caulinodans ORS571: similarity of the fixB product with eukaryotic flavoproteins, characterization of fixX, and identification of nifW.

    Science.gov (United States)

    Arigoni, F; Kaminski, P A; Hennecke, H; Elmerich, C

    1991-03-01

    The nucleotide sequence of a 4.1 kb DNA fragment containing the fixABC region of Azorhizobium caulinodans was established. The three gene products were very similar to the corresponding polypeptides of Rhizobium meliloti. The C-terminal domains of both fixB products displayed a high degree of similarity with the alpha-subunits of rat and human electron transfer flavoproteins, suggesting a role for the FixB protein in a redox reaction. Two open reading frames (ORF) were found downstream of fixC. The first ORF was identified as fixX on the basis of sequence homology with fixX from several Rhizobium and Bradyrhizobium strains. The second ORF potentially encoded a 69 amino acid product and was found to be homologous to a DNA region in the Rhodobacter capsulatus nif cluster I. Insertion mutagenesis of the A. caulinodans fixX gene conferred a Nif- phenotype to bacteria growth in the free-living state and a Fix- phenotype in symbiotic association with the host plant Sesbania rostrata. A crude extract from the fixX mutant had no nitrogenase activity. Furthermore, data presented in this paper also indicate that the previously identified nifO gene located upstream of fixA was probably a homologue of the nifW gene of Klebsiella pneumoniae and Azotobacter vinelandii. PMID:1850088

  12. Flavoprotein-mediated tellurite reduction: structural basis and applications to the synthesis of tellurium-containing nanostructures

    Directory of Open Access Journals (Sweden)

    Mauricio Arenas-Salinas

    2016-07-01

    Full Text Available The tellurium oxyanion tellurite (TeO32- is extremely harmful for most organisms. It has been suggested that a potential bacterial tellurite resistance mechanism would consist of an enzymatic, NAD(PH-dependent, reduction to the less toxic form elemental tellurium (Te0. To date, a number of enzymes such as catalase, type II NADH dehydrogenase and terminal oxidases from the electron transport chain, nitrate reductases, and dihydrolipoamide dehydrogenase (E3, among others, have been shown to display tellurite-reducing activity. This activity is generically referred to as tellurite reductase (TR. Bioinformatic data resting on some of the abovementioned enzymes enabled the identification of common structures involved in tellurite reduction including vicinal catalytic cysteine residues and the FAD/NAD(P+-binding domain, which is characteristic of some flavoproteins. Along this line, thioredoxin reductase (TrxB, alkyl hydroperoxide reductase (AhpF, glutathione reductase (GorA, mercuric reductase (MerA, NADH: flavorubredoxin reductase (NorW, dihydrolipoamide dehydrogenase, and the putative oxidoreductase YkgC from Escherichia coli or environmental bacteria were purified and assessed for TR activity. All of them displayed in vitro TR activity at the expense of NADH or NADPH oxidation. In general, optimal reducing conditions occurred around pH 9-10 and 37 °C.Enzymes exhibiting strong TR activity produced Te-containing nanostructures (TeNS. While GorA and AhpF generated TeNS of 75 nm average diameter, E3 and YkgC produced larger structures (> 100 nm. Electron-dense structures were observed in cells over-expressing genes encoding TrxB, GorA and YkgC.

  13. Flavoprotein-Mediated Tellurite Reduction: Structural Basis and Applications to the Synthesis of Tellurium-Containing Nanostructures

    Science.gov (United States)

    Arenas-Salinas, Mauricio; Vargas-Pérez, Joaquín I.; Morales, Wladimir; Pinto, Camilo; Muñoz-Díaz, Pablo; Cornejo, Fabián A.; Pugin, Benoit; Sandoval, Juan M.; Díaz-Vásquez, Waldo A.; Muñoz-Villagrán, Claudia; Rodríguez-Rojas, Fernanda; Morales, Eduardo H.; Vásquez, Claudio C.; Arenas, Felipe A.

    2016-01-01

    The tellurium oxyanion tellurite (TeO32-) is extremely harmful for most organisms. It has been suggested that a potential bacterial tellurite resistance mechanism would consist of an enzymatic, NAD(P)H-dependent, reduction to the less toxic form elemental tellurium (Te0). To date, a number of enzymes such as catalase, type II NADH dehydrogenase and terminal oxidases from the electron transport chain, nitrate reductases, and dihydrolipoamide dehydrogenase (E3), among others, have been shown to display tellurite-reducing activity. This activity is generically referred to as tellurite reductase (TR). Bioinformatic data resting on some of the abovementioned enzymes enabled the identification of common structures involved in tellurite reduction including vicinal catalytic cysteine residues and the FAD/NAD(P)+-binding domain, which is characteristic of some flavoproteins. Along this line, thioredoxin reductase (TrxB), alkyl hydroperoxide reductase (AhpF), glutathione reductase (GorA), mercuric reductase (MerA), NADH: flavorubredoxin reductase (NorW), dihydrolipoamide dehydrogenase, and the putative oxidoreductase YkgC from Escherichia coli or environmental bacteria were purified and assessed for TR activity. All of them displayed in vitro TR activity at the expense of NADH or NADPH oxidation. In general, optimal reducing conditions occurred around pH 9–10 and 37°C. Enzymes exhibiting strong TR activity produced Te-containing nanostructures (TeNS). While GorA and AhpF generated TeNS of 75 nm average diameter, E3 and YkgC produced larger structures (>100 nm). Electron-dense structures were observed in cells over-expressing genes encoding TrxB, GorA, and YkgC. PMID:27507969

  14. Flavoprotein-Mediated Tellurite Reduction: Structural Basis and Applications to the Synthesis of Tellurium-Containing Nanostructures.

    Science.gov (United States)

    Arenas-Salinas, Mauricio; Vargas-Pérez, Joaquín I; Morales, Wladimir; Pinto, Camilo; Muñoz-Díaz, Pablo; Cornejo, Fabián A; Pugin, Benoit; Sandoval, Juan M; Díaz-Vásquez, Waldo A; Muñoz-Villagrán, Claudia; Rodríguez-Rojas, Fernanda; Morales, Eduardo H; Vásquez, Claudio C; Arenas, Felipe A

    2016-01-01

    The tellurium oxyanion tellurite (TeO3 (2-)) is extremely harmful for most organisms. It has been suggested that a potential bacterial tellurite resistance mechanism would consist of an enzymatic, NAD(P)H-dependent, reduction to the less toxic form elemental tellurium (Te(0)). To date, a number of enzymes such as catalase, type II NADH dehydrogenase and terminal oxidases from the electron transport chain, nitrate reductases, and dihydrolipoamide dehydrogenase (E3), among others, have been shown to display tellurite-reducing activity. This activity is generically referred to as tellurite reductase (TR). Bioinformatic data resting on some of the abovementioned enzymes enabled the identification of common structures involved in tellurite reduction including vicinal catalytic cysteine residues and the FAD/NAD(P)(+)-binding domain, which is characteristic of some flavoproteins. Along this line, thioredoxin reductase (TrxB), alkyl hydroperoxide reductase (AhpF), glutathione reductase (GorA), mercuric reductase (MerA), NADH: flavorubredoxin reductase (NorW), dihydrolipoamide dehydrogenase, and the putative oxidoreductase YkgC from Escherichia coli or environmental bacteria were purified and assessed for TR activity. All of them displayed in vitro TR activity at the expense of NADH or NADPH oxidation. In general, optimal reducing conditions occurred around pH 9-10 and 37°C. Enzymes exhibiting strong TR activity produced Te-containing nanostructures (TeNS). While GorA and AhpF generated TeNS of 75 nm average diameter, E3 and YkgC produced larger structures (>100 nm). Electron-dense structures were observed in cells over-expressing genes encoding TrxB, GorA, and YkgC. PMID:27507969

  15. The flavoprotein Mcap0476 (RlmFO) catalyzes m5U1939 modification in Mycoplasma capricolum 23S rRNA

    DEFF Research Database (Denmark)

    Lartigue, Carole; Lebaudy, Anne; Blanchard, Alain;

    2014-01-01

    group donor. One noteworthy exception is seen in some bacteria, where the conserved tRNA methylation at m5U54 is added by the enzyme TrmFO using flavin adenine dinucleotide together with N5,N10-methylenetetrahydrofolate as the one-carbon donor. The minimalist bacterium Mycoplasma capricolum possesses...... specifically modifies m5U1939 in 23S rRNA, a conserved methylation catalyzed by AdoMet-dependent enzymes in all other characterized bacteria. The Mcap0476 methyltransferase (renamed RlmFO) represents the first folate-dependent flavoprotein seen to modify ribosomal RNA....

  16. Identification of a Conserved Sequence in Flavoproteins Essential for the Correct Conformation and Activity of the NADH Oxidase NoxE of Lactococcus lactis ▿ †

    OpenAIRE

    Tachon, Sybille; Chambellon, Emilie; Yvon, Mireille

    2011-01-01

    Water-forming NADH oxidases (encoded by noxE, nox2, or nox) are flavoproteins generally implicated in the aerobic survival of microaerophilic bacteria, such as lactic acid bacteria. However, some natural Lactococcus lactis strains produce an inactive NoxE. We examined the role of NoxE in the oxygen tolerance of L. lactis in the rich synthetic medium GM17. Inactivation of noxE suppressed 95% of NADH oxidase activity but only slightly affected aerobic growth, oxidative stress resistance, and NA...

  17. Characterization of a nif-regulated flavoprotein (FprA) from Rhodobacter capsulatus. Redox properties and molecular interaction with a [2Fe-2S] ferredoxin.

    Science.gov (United States)

    Jouanneau, Y; Meyer, C; Asso, M; Guigliarelli, B; Willison, J C

    2000-02-01

    A flavoprotein from Rhodobacter capsulatus was purified as a recombinant (His)6-tag fusion from an Escherichia coli clone over-expressing the fprA structural gene. The FprA protein is a homodimer containing one molecule of FMN per 48-kDa monomer. Reduction of the flavoprotein by dithionite showed biphasic kinetics, starting with a fast step of semiquinone (SQ) formation, and followed by a slow reduction of the SQ. This SQ was in the anionic form as shown by EPR and optical spectroscopies. Spectrophotometric titration gave a midpoint redox potential for the oxidized/SQ couple of Em1 = +20 mV (pH 8.0), whereas the SQ/hydroquinone couple could not be titrated due to the thermodynamic instability of SQ associated with its slow reduction process. The inability to detect the intermediate form, SQ, upon oxidative titration confirmed this instability and led to an estimate of Em2 - Em1 of > 80 mV. The reduction of SQ by dithionite was significantly accelerated when the [2Fe-2S] ferredoxin FdIV was used as redox mediator. The midpoint redox potential of this ferredoxin was determined to be -275 +/- 2 mV at pH 7.5, consistent with FdIV serving as electron donor to FprA in vivo. FdIV and FprA were found to cross-react when incubated together with the 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, giving a covalent complex with an Mr of approximately 60 000. Formation of this complex was unaffected by the redox states of the two proteins. Other [2Fe-2S] ferredoxins, including FdV and FdVI from R. capsulatus, were ineffective as electron carriers to FprA, and cross-reacted poorly with the flavoprotein. The possible function of FprA with regard to nitrogen fixation was investigated using an fprA-deleted mutant. Although nitrogenase activity was significantly reduced in the mutant compared with the wild-type strain, nitrogen fixation was apparently unaffected by the fprA deletion even under iron limitation or microaerobic conditions.

  18. Skeletal Muscle Magnetic Resonance Imaging of the Lower Limbs in Late-onset Lipid Storage Myopathy with Electron Transfer Flavoprotein Dehydrogenase Gene Mutations

    Institute of Scientific and Technical Information of China (English)

    Xin-Yi Liu; Ming Jin; Zhi-Qiang Wang; Dan-Ni Wang; Jun-Jie He; Min-Ting Lin; Hong-Xia Fu

    2016-01-01

    Background:Lipid storage myopathy (LSM) is a genetically heterogeneous group with variable clinical phenotypes.Late-onset multiple acyl-coenzyme A dehydrogenation deficiency (MADD) is a rather common form of LSM in China.Diagnosis and clinical management of it remain challenging,especially without robust muscle biopsy result and genetic detection.As the noninvasion and convenience,muscle magnetic resonance imaging (MRI) is a helpful assistant,diagnostic tool for neuromuscular disorders.However,the disease-specific MRI patterns of muscle involved and its diagnostic value in late-onset MADD have not been systematic analyzed.Methods:We assessed the MRI pattern and fat infiltration degree of the lower limb muscles in 28 late-onset MADD patients,combined with detailed clinical features and gene spectrum.Fat infiltration degree of the thigh muscle was scored while that ofgluteus was described as obvious or not.Associated muscular atrophy was defined as obvious muscle bulk reduction.Results:The mean scores were significantly different among the anterior,medial,and posterior thigh muscle groups.The mean of fat infiltration scores on posterior thigh muscle group was significantly higher than either anterior or medial thigh muscle group (P < 0.001).Moreover,the mean score on medial thigh muscle group was significantly higher than that of anterior thigh muscle group (P < 0.01).About half of the patients displayed fat infiltration and atrophy in gluteus muscles.Of 28 patients,12 exhibited atrophy in medial and/or posterior thigh muscle groups,especially in posterior thigh muscle group.Muscle edema pattern was not found in all the patients.Conclusions:Late-onset MADD patients show a typical muscular imaging pattern of fat infiltration and atrophy on anterior,posterior,and medial thigh muscle groups,with major involvement of posterior thigh muscle group and gluteus muscles and a sparing involvement of anterior thigh compartment.Our findings also suggest that muscle MRI of lower limbs is a helpful tool in guiding clinical evaluation on late-onset MADD.

  19. Cloning and characterization of sulfite dehydrogenase, two c-type cytochromes, and a flavoprotein of Paracoccus denitrificans GB17: essential role of sulfite dehydrogenase in lithotrophic sulfur oxidation.

    Science.gov (United States)

    Wodara, C; Bardischewsky, F; Friedrich, C G

    1997-08-01

    of the flavoprotein of flavocytochrome c of Chromatium vinosum, suggesting the involvement of the flavoprotein in thiosulfate oxidation of P. denitrificans GB17. PMID:9260941

  20. The flavoproteins CryD and VvdA cooperate with the white collar protein WcoA in the control of photocarotenogenesis in Fusarium fujikuroi.

    Directory of Open Access Journals (Sweden)

    Marta Castrillo

    Full Text Available Light stimulates carotenoid biosynthesis in the ascomycete fungus Fusarium fujikuroi through transcriptional activation of the structural genes of the pathway carRA, carB, and cart, but the molecular basis of this photoresponse is unknown. The F. fujikuroi genome contains genes for different predicted photoreceptors, including the WC protein WcoA, the DASH cryptochrome CryD and the Vivid-like flavoprotein VvdA. We formerly found that null mutants of wcoA, cryD or vvdA exhibit carotenoid photoinduction under continuous illumination. Here we show that the wild type exhibits a biphasic response in light induction kinetics experiments, with a rapid increase in carotenoid content in the first hours, a transient arrest and a subsequent slower increase. The mutants of the three photoreceptors show different kinetic responses: the wcoA mutants are defective in the rapid response, the cryD mutants are affected in the slower response, while the fast and slow responses were respectively enhanced and attenuated in the vvdA mutants. Transcriptional analyses of the car genes revealed a strong reduction of dark and light-induced transcript levels in the wcoA mutants, while minor or no reductions were found in the cryD mutants. Formerly, we found no change on carRA and carB photoinduction in vvdA mutants. Taken together, our data suggest a cooperative participation of WcoA and CryD in early and late stages of photoinduction of carotenoid biosynthesis in F. fujikuroi, and a possible modulation of WcoA activity by VvdA. An unexpected transcriptional induction by red light of vvdA, cryD and carRA genes suggest the participation of an additional red light-absorbing photoreceptor.

  1. Mitochondrial targeting of human NADH dehydrogenase (ubiquinone flavoprotein 2 (NDUFV2 and its association with early-onset hypertrophic cardiomyopathy and encephalopathy

    Directory of Open Access Journals (Sweden)

    Kao Mou-Chieh

    2011-05-01

    Full Text Available Abstract Background NADH dehydrogenase (ubiquinone flavoprotein 2 (NDUFV2, containing one iron sulfur cluster ([2Fe-2S] binuclear cluster N1a, is one of the core nuclear-encoded subunits existing in human mitochondrial complex I. Defects in this subunit have been associated with Parkinson's disease, Alzheimer's disease, Bipolar disorder, and Schizophrenia. The aim of this study is to examine the mitochondrial targeting of NDUFV2 and dissect the pathogenetic mechanism of one human deletion mutation present in patients with early-onset hypertrophic cardiomyopathy and encephalopathy. Methods A series of deletion and point-mutated constructs with the c-myc epitope tag were generated to identify the location and sequence features of mitochondrial targeting sequence for NDUFV2 in human cells using the confocal microscopy. In addition, various lengths of the NDUFV2 N-terminal and C-terminal fragments were fused with enhanced green fluorescent protein to investigate the minimal region required for correct mitochondrial import. Finally, a deletion construct that mimicked the IVS2+5_+8delGTAA mutation in NDUFV2 gene and would eventually produce a shortened NDUFV2 lacking 19-40 residues was generated to explore the connection between human gene mutation and disease. Results We identified that the cleavage site of NDUFV2 was located around amino acid 32 of the precursor protein, and the first 22 residues of NDUFV2 were enough to function as an efficient mitochondrial targeting sequence to carry the passenger protein into mitochondria. A site-directed mutagenesis study showed that none of the single-point mutations derived from basic, hydroxylated and hydrophobic residues in the NDUFV2 presequence had a significant effect on mitochondrial targeting, while increasing number of mutations in basic and hydrophobic residues gradually decreased the mitochondrial import efficacy of the protein. The deletion mutant mimicking the human early-onset hypertrophic

  2. Flavoprotein oxidases : classification and applications

    NARCIS (Netherlands)

    Dijkman, Willem P.; de Gonzalo, Gonzalo; Mattevi, Andrea; Fraaije, Marco W.

    2013-01-01

    This review provides an overview of oxidases that utilise a flavin cofactor for catalysis. This class of oxidative flavoenzymes has shown to harbour a large number of biotechnologically interesting enzymes. Applications range from their use as biocatalysts for the synthesis of pharmaceutical compoun

  3. Quantum effects in ultrafast electron transfers within cryptochromes.

    Science.gov (United States)

    Firmino, Thiago; Mangaud, Etienne; Cailliez, Fabien; Devolder, Adrien; Mendive-Tapia, David; Gatti, Fabien; Meier, Christoph; Desouter-Lecomte, Michèle; de la Lande, Aurélien

    2016-08-21

    Cryptochromes and photolyases are flavoproteins that may undergo ultrafast charge separation upon electronic excitation of their flavin cofactors. Charge separation involves chains of three or four tryptophan residues depending on the protein of interest. The molecular mechanisms of these processes are not completely clear. In the present work we investigate the relevance of quantum effects like the occurrence of nuclear tunneling and of coherences upon charge transfer in Arabidopsis thaliana cryptochromes. The possible breakdown of the Condon approximation is also investigated. We have devised a simulation protocol based on the realization of molecular dynamics simulations on diabatic potential energy surfaces defined at the hybrid constrained density functional theory/molecular mechanics level. The outcomes of the simulations are analyzed through various dedicated kinetics schemes related to the Marcus theory that account for the aforementioned quantum effects. MD simulations also provide a basic material to define realistic model Hamiltonians for subsequent quantum dissipative dynamics. To carry out quantum simulations, we have implemented an algorithm based on the Hierarchical Equations of Motion. With this new tool in hand we have been able to model the electron transfer chain considering either two- or three-state models. Kinetic models and quantum simulations converge to the conclusion that quantum effects have a significant impact on the rate of charge separation. Nuclear tunneling involving atoms of the tryptophan redox cofactors as well as of the environment (protein atoms and water molecules) is significant. On the other hand non-Condon effects are negligible in most simulations. Taken together, the results of the present work provide new insights into the molecular mechanisms controlling charge separation in this family of flavoproteins. PMID:27427185

  4. A polymorphic variant in the human electron transfer flavoprotein alpha-chain (alpha-T171) displays decreased thermal stability and is overrepresented in very-long-chain acyl-CoA dehydrogenase-deficient patients with mild childhood presentation

    DEFF Research Database (Denmark)

    Bross, P; Pedersen, P; Nyholm, M;

    1999-01-01

    , whereas the two variants of the beta-M/T154 polymorphism did not differ. We wished to test the hypothesis that these polymorphisms might constitute susceptibility factors and therefore determined their allele and genotype frequencies in (i) control individuals, (ii) medium-chain acyl-CoA dehydrogenase......-deficient patients homozygous for the K304E mutation (MCAD E304), (iii) a group of patients with elevated urinary excretion of ethylmalonic acid (EMA) possibly due to decreased short-chain acyl-CoA dehydrogenase activity, and (iv) in patients with proven deficiency of very-long-chain acyl-CoA dehydrogenase (VLCAD......). No significant overrepresentations or underrepresentations were found in the first two patient groups, suggesting that the polymorphisms studied are not significant susceptibility factors in either the MCAD E304 or the EMA patient group. However, in the VLCAD deficient patients the alpha-T171 variant (decreased...

  5. Transfer Pricing

    DEFF Research Database (Denmark)

    Nielsen, Søren Bo

    2014-01-01

    Against a background of rather mixed evidence about transfer pricing practices in multinational enterprises (MNEs) and varying attitudes on the part of tax authorities, this paper explores how multiple aims in transfer pricing can be pursued across four different transfer pricing regimes. A MNE h...

  6. Transfer Pricing

    DEFF Research Database (Denmark)

    Rohde, Carsten; Rossing, Christian Plesner

    trade internally as the units have to decide what prices should be paid for such inter-unit transfers. One important challenge is to uncover the consequences that different transfer prices have on the willingness in the organizational units to coordinate activities and trade internally. At the same time...

  7. "Transfer Shock" or "Transfer Ecstasy?"

    Science.gov (United States)

    Nickens, John M.

    The alleged characteristic drop in grade point average (GPA) of transfer students and the subsequent rise in GPA was investigated in this study. No statistically significant difference was found in first term junior year GPA between junior college transfers and native Florida State University students after the variance accounted for by the…

  8. Alcohol oxidase: A complex peroxisomal, oligomeric flavoprotein

    OpenAIRE

    Ozimek, Paulina; Veenhuis, Marten; van der Klei, Ida J.

    2005-01-01

    Alcohol oxidase (AO) is the key enzyme of methanol metabolism in methylotrophic yeast species. It catalyses the first step of methanol catabolism, namely its oxidation to formaldehyde with concomitant production of hydrogen peroxide. In its mature active form, AO is a molecule of high molecular mass (600 kDa) that consists of eight identical subunits, each of which carry one non-covalently bound flavin adenine nucleotide (FAD) molecule as the prosthetic group. In vivo, the protein is compartm...

  9. Restoration of contralateral representation in the mouse somatosensory cortex after crossing nerve transfer.

    Directory of Open Access Journals (Sweden)

    Haruyoshi Yamashita

    Full Text Available Avulsion of spinal nerve roots in the brachial plexus (BP can be repaired by crossing nerve transfer via a nerve graft to connect injured nerve ends to the BP contralateral to the lesioned side. Sensory recovery in these patients suggests that the contralateral primary somatosensory cortex (S1 is activated by afferent inputs that bypassed to the contralateral BP. To confirm this hypothesis, the present study visualized cortical activity after crossing nerve transfer in mice through the use of transcranial flavoprotein fluorescence imaging. In naïve mice, vibratory stimuli applied to the forepaw elicited localized fluorescence responses in the S1 contralateral to the stimulated side, with almost no activity in the ipsilateral S1. Four weeks after crossing nerve transfer, forepaw stimulation in the injured and repaired side resulted in cortical responses only in the S1 ipsilateral to the stimulated side. At eight weeks after crossing nerve transfer, forepaw stimulation resulted in S1 cortical responses of both hemispheres. These cortical responses were abolished by cutting the nerve graft used for repair. Exposure of the ipsilateral S1 to blue laser light suppressed cortical responses in the ipsilateral S1, as well as in the contralateral S1, suggesting that ipsilateral responses propagated to the contralateral S1 via cortico-cortical pathways. Direct high-frequency stimulation of the ipsilateral S1 in combination with forepaw stimulation acutely induced S1 bilateral cortical representation of the forepaw area in naïve mice. Cortical responses in the contralateral S1 after crossing nerve transfer were reduced in cortex-restricted heterotypic GluN1 (NMDAR1 knockout mice. Functional bilateral cortical representation was not clearly observed in genetically manipulated mice with impaired cortico-cortical pathways between S1 of both hemispheres. Taken together, these findings strongly suggest that activity-dependent potentiation of cortico

  10. Facilitating Transfers

    DEFF Research Database (Denmark)

    Kjær, Poul F.

    The concept of governance has mutated into an all‐embracing buzz‐word characterised by a low degree of conceptual precision and empirical focus. This paper therefore suggests a narrower and more precise understanding of governance and the regulatory function it fulfils by advancing the argument t...... and different types of transfers between them. It will, furthermore, explore the role and “quality” of different types of regulatory governance frameworks in relation to the facilitation, stabilisation and justification of transfers....... that the essential functional and normative purpose of regulatory governance is to facilitate, stabilise and justify the transfer of condensed social components (such as economic capital and products, political decisions, legal judgements, religious beliefs and scientific knowledge) from one social contexts...

  11. Blastocyst Transfer

    OpenAIRE

    sprotocols

    2014-01-01

    ### Method: Blastocyst transfer is usually performed 24 hours after aggregation when the morulae have become expanded blastocysts and on the same day as injection. A little time is given between injection and transfer to allow blastocysts to re-expand. **The Recipient** Careful selection of the recipient is most important as the pups are the end result of a lot of hard work. Two strains of mice are used:RB Swiss and (CBA*C57BL6/J)f1. RB Swiss are quiet and make excellent mothers ...

  12. Heat transfer

    CERN Document Server

    Holman, J P

    2010-01-01

    As one of the most popular heat transfer texts, Jack Holman's "Heat Transfer" is noted for its clarity, accessible approach, and inclusion of many examples and problem sets. The new tenth edition retains the straight-forward, to-the-point writing style while covering both analytical and empirical approaches to the subject. Throughout the book, emphasis is placed on physical understanding while, at the same time, relying on meaningful experimental data in those situations that do not permit a simple analytical solution. New examples and templates provide students with updated resources for computer-numerical solutions.

  13. Technology transfer

    International Nuclear Information System (INIS)

    This paper emphasizes in the specific areas of design, engineering and component production. This paper presents what Framatome has to offer in these areas and its export oriented philosophy. Then, a typical example of this technology transfer philosophy is the collaboration with the South Korean firm, Korea Heavy Industries Corporation (KHIC) for the supply of KNU 9 and KNU 10 power stations

  14. Sophisticated transfer

    NARCIS (Netherlands)

    Reinhart, T.

    2006-01-01

    On the eve of the Iraq war, fears were expressed in different circles that under the cover of war, Israel may attempt a transfer of Palestinians in the “seam line” area of the northern West Bank (Kalkilya, Tulkarem). Last week, the army produced a scene from this scenario. On April 2 at 3 AM, a larg

  15. moisture transfer

    Directory of Open Access Journals (Sweden)

    Don Kulasiri

    2005-01-01

    model drying porous materials. Coupled partial differential equations governing the moisture and heat transfer can be solved using numerical techniques, and in this paper we solve them analytically in a setting suitable for industrial drying situations. We discuss the nature of the solutions using the physical properties of Pinus radiata. It is shown that the temperature gradients play a significant role in deciding the moisture profiles within the material when thickness is large and that models based only on moisture potential gradients may not be sufficient to explain the drying phenomena in moist porous materials.

  16. Historiographical transfers

    Directory of Open Access Journals (Sweden)

    Jacques-Emmanuel Bernard

    2008-06-01

    Full Text Available “There are other signs that the Greeks began to notice the peculiarities of Roman social life and of Roman behavior in international affairs. True enough, the famous set of Roman values – fides, constantia, severitas, auctoritas, etc., – was discovered for the first time by German professors during the First World War, and helped their pupils to mark time while Hitler was deciding what to do with the classics”.Arnoldo Momigliano, Alien Wisdom. For anyone interested in the transfer of historio...

  17. Heat transfer

    CERN Document Server

    Jorge, Kubie; Thomas, Grassie

    2012-01-01

    A core task of engineers is to analyse energy related problems. The analytical treatment is usually based on principles of thermodynamics, fluid mechanics and heat transfer, but is increasingly being handled computationally.This unique resource presents a practical textbook, written for both undergraduates and professionals, with a series of over 60 computer workbooks on an accompanying CD.The book emphasizes how complex problems can be deconstructed into a series of simple steps. All thermophysical property computations are illustrated using diagrams within text and on the compani

  18. Technology Transfer

    Science.gov (United States)

    Bullock, Kimberly R.

    1995-01-01

    The development and application of new technologies in the United States has always been important to the economic well being of the country. The National Aeronautics and Space Administration (NASA) has been an important source of these new technologies for almost four decades. Recently, increasing global competition has emphasized the importance of fully utilizing federally funded technologies. Today NASA must meet its mission goals while at the same time, conduct research and development that contributes to securing US economic growth. NASA technologies must be quickly and effectively transferred into commercial products. In order to accomplish this task, NASA has formulated a new way of doing business with the private sector. Emphasis is placed on forming mutually beneficial partnerships between NASA and US industry. New standards have been set in response to the process that increase effectiveness, efficiency, and timely customer response. This summer I have identified potential markets for two NASA inventions: including the Radially Focused Eddy Current Sensor for Characterization of Flaws in Metallic Tubing and the Radiographic Moire. I have also worked to establish a cooperative program with TAG, private industry, and a university known as the TAG/Industry/Academia Program.

  19. Trends in Technology Transfer.

    Science.gov (United States)

    Starnick, Jurgen

    1988-01-01

    Various forms of technology transfer in Europe and North America are discussed including research contracts, cooperative research centers, and personnel transfer. Examples of approaches to technology transfer are given and the establishment of personnel transfer is discussed. Preconditions for successful technology transfer in the future are…

  20. Thermodynamic basis of electron transfer in dihydroorotate dehydrogenase B from Lactococcus lactis: analysis by potentiometry, EPR spectroscopy, and ENDOR spectroscopy.

    Science.gov (United States)

    Mohsen, Al-Walid A; Rigby, Stephen E J; Jensen, Kaj Frank; Munro, Andrew W; Scrutton, Nigel S

    2004-06-01

    signal is assigned to the formation of a spin interacting state between the FMN semiquinone species and the reduced 2Fe-2S center. Reduction of DHODB using an excess of NADH or dihydroorotate produces EPR spectra that are distinct from those produced by dithionite. From potentiometric studies, the reduction of the 2Fe-2S center and the reduction of the FMN occur concomitantly. The study provides a detailed thermodynamic framework for electron transfer in this complex iron-sulfur flavoprotein.

  1. Cryogenic heat transfer

    CERN Document Server

    Barron, Randall F

    2016-01-01

    Cryogenic Heat Transfer, Second Edition continues to address specific heat transfer problems that occur in the cryogenic temperature range where there are distinct differences from conventional heat transfer problems. This updated version examines the use of computer-aided design in cryogenic engineering and emphasizes commonly used computer programs to address modern cryogenic heat transfer problems. It introduces additional topics in cryogenic heat transfer that include latent heat expressions; lumped-capacity transient heat transfer; thermal stresses; Laplace transform solutions; oscillating flow heat transfer, and computer-aided heat exchanger design. It also includes new examples and homework problems throughout the book, and provides ample references for further study.

  2. Thermal radiation heat transfer

    CERN Document Server

    Howell, John R; Siegel, Robert

    2016-01-01

    Further expanding on the changes made to the fifth edition, Thermal Radiation Heat Transfer, 6th Edition continues to highlight the relevance of thermal radiative transfer and focus on concepts that develop the radiative transfer equation (RTE). The book explains the fundamentals of radiative transfer, introduces the energy and radiative transfer equations, covers a variety of approaches used to gauge radiative heat exchange between different surfaces and structures, and provides solution techniques for solving the RTE.

  3. AcEST: DK963528 [AcEST

    Lifescience Database Archive (English)

    Full Text Available LNKEK--ATVERE 162 >sp|Q54YZ4|ETFB_DICDI Electron transfer flavoprotein subunit beta OS=Dictyostelium discoideum GN=etfb...WPQGTFASQVTLE--GDKLKVERE 165 >sp|Q68FU3|ETFB_RAT Electron transfer flavoprotein subunit beta OS=Rattus norvegicus GN=Etfb...TFASQVTLE--GDKVKVERE 165 >sp|Q9DCW4|ETFB_MOUSE Electron transfer flavoprotein subunit beta OS=Mus musculus GN=Etfb

  4. Convective heat transfer

    CERN Document Server

    Kakac, Sadik; Pramuanjaroenkij, Anchasa

    2014-01-01

    Intended for readers who have taken a basic heat transfer course and have a basic knowledge of thermodynamics, heat transfer, fluid mechanics, and differential equations, Convective Heat Transfer, Third Edition provides an overview of phenomenological convective heat transfer. This book combines applications of engineering with the basic concepts of convection. It offers a clear and balanced presentation of essential topics using both traditional and numerical methods. The text addresses emerging science and technology matters, and highlights biomedical applications and energy technologies. What’s New in the Third Edition: Includes updated chapters and two new chapters on heat transfer in microchannels and heat transfer with nanofluids Expands problem sets and introduces new correlations and solved examples Provides more coverage of numerical/computer methods The third edition details the new research areas of heat transfer in microchannels and the enhancement of convective heat transfer with nanofluids....

  5. Introduction to heat transfer

    CERN Document Server

    SUNDÉN, B

    2012-01-01

    Presenting the basic mechanisms for transfer of heat, Introduction to Heat Transfer gives a deeper and more comprehensive view than existing titles on the subject. Derivation and presentation of analytical and empirical methods are provided for calculation of heat transfer rates and temperature fields as well as pressure drop. The book covers thermal conduction, forced and natural laminar and turbulent convective heat transfer, thermal radiation including participating media, condensation, evaporation and heat exchangers.

  6. Transfer of gaming

    NARCIS (Netherlands)

    Korteling, J.E.

    2012-01-01

    An overview is provided of the activities and results op GATE WP 4.4 entiteld Transfer of Gaming (ToG). This work package has produced the principles and methodologies concerning optimalization and measurement of transfer of training in serious gaming. In addition, true transfer of job-specific comp

  7. Electron transfer reactions

    CERN Document Server

    Cannon, R D

    2013-01-01

    Electron Transfer Reactions deals with the mechanisms of electron transfer reactions between metal ions in solution, as well as the electron exchange between atoms or molecules in either the gaseous or solid state. The book is divided into three parts. Part 1 covers the electron transfer between atoms and molecules in the gas state. Part 2 tackles the reaction paths of oxidation states and binuclear intermediates, as well as the mechanisms of electron transfer. Part 3 discusses the theories and models of the electron transfer process; theories and experiments involving bridged electron transfe

  8. Transfer function combinations

    KAUST Repository

    Zhou, Liang

    2012-10-01

    Direct volume rendering has been an active area of research for over two decades. Transfer function design remains a difficult task since current methods, such as traditional 1D and 2D transfer functions, are not always effective for all data sets. Various 1D or 2D transfer function spaces have been proposed to improve classification exploiting different aspects, such as using the gradient magnitude for boundary location and statistical, occlusion, or size metrics. In this paper, we present a novel transfer function method which can provide more specificity for data classification by combining different transfer function spaces. In this work, a 2D transfer function can be combined with 1D transfer functions which improve the classification. Specifically, we use the traditional 2D scalar/gradient magnitude, 2D statistical, and 2D occlusion spectrum transfer functions and combine these with occlusion and/or size-based transfer functions to provide better specificity. We demonstrate the usefulness of the new method by comparing to the following previous techniques: 2D gradient magnitude, 2D occlusion spectrum, 2D statistical transfer functions and 2D size based transfer functions. © 2012 Elsevier Ltd.

  9. 76 FR 44761 - Remittance Transfers

    Science.gov (United States)

    2011-07-27

    ... Electronic Fund Transfer Act (EFTA), as an example of money transfer instruments Federal credit unions (FCUs... receiving international and domestic electronic fund transfers'' after the words ``money orders'' from... checks, money orders, and other similar transfer instruments, including international and...

  10. Waste Transfer Stations

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund

    2011-01-01

    tion and transport is usually the most costly part of any waste management system; and when waste is transported over a considerable distance or for a long time, transferring the waste from the collection vehicles to more efficient transportation may be economically beneficial. This involves...... a transfer station where the transfer takes place. These stations may also be accessible by private people, offering flexibility to the waste system, including facilities for bulky waste, household hazardous waste and recyclables. Waste transfer may also take place on the collection route from small...... satellite collection vehicles to large compacting vehicles that cannot effectively travel small streets and alleys within the inner city or in residential communities with narrow roads. However, mobile transfer is not dealt with in this chapter, which focuses on stationary transfer stations. This chapter...

  11. HEAT TRANSFER FLUIDS

    OpenAIRE

    Lenert, Andrej; Nam, Youngsuk; Wang, Evelyn N.

    2012-01-01

    The choice of heat transfer fluids has significant effects on the performance, cost, and reliability of solar thermal systems. In this chapter, we evaluate existing heat transfer fluids such as oils and molten salts based on a new figure of merit capturing the combined effects of thermal storage capacity, convective heat transfer characteristics, and hydraulic performance of the fluids. Thermal stability, freezing point, and safety issues are also discussed. Through a comparative analysis, we...

  12. Gas transfer system

    International Nuclear Information System (INIS)

    The state of work on the Vivitron gas transfer system and the system functions are summarized. The system has to: evacuate the Vivitron reservoir; transfer gas from storage tanks to the Vivitron; recirculate gas during operation; transfer gas from the Vivitron to storage tanks; and assure air input. The system is now being installed. Leak alarms are given by SF6 detectors, which set off a system of forced ventilation. Another system continuously monitors the amount of SF6 in the tanks

  13. Memristive Transfer Matrices

    OpenAIRE

    Mouttet, Blaise

    2010-01-01

    An electrical analysis is performed for a memristor crossbar array integrated with operational amplifiers including the effects of parasitic or contact resistances. It is shown that the memristor crossbar array can act as a transfer matrix for a multiple input-multiple output signal processing system. Special cases of the transfer matrix are described related to reconfigurable analog filters, waveform generators, analog computing, and pattern similarity. Keywords: transfer matrix, memristor, ...

  14. Memristive Transfer Matrices

    CERN Document Server

    Mouttet, Blaise

    2010-01-01

    An electrical analysis is performed for a memristor crossbar array integrated with operational amplifiers including the effects of parasitic or contact resistances. It is shown that the memristor crossbar array can act as a transfer matrix for a multiple input-multiple output signal processing system. Special cases of the transfer matrix are described related to reconfigurable analog filters, waveform generators, analog computing, and pattern similarity. Keywords: transfer matrix, memristor, analog electronics, crossbar, operational amplifier, reconfigurable electronics

  15. Biomechanics of Tendon Transfers.

    Science.gov (United States)

    Livermore, Andrew; Tueting, Jonathan L

    2016-08-01

    The transfer of tendons in the upper extremity is a powerful technique to restore function to a partially paralyzed hand. The biomechanical principles of muscle tension and tendon excursion dictate motor function both in the native as well as transferred states. Appropriately tensioning transferred tendons to maximize the function of the associated muscle remains an area of focused research. Newer methods of tendon coaptation have proven similar in strength to the standard Pulvertaft weave, affording more options to the surgeon. PMID:27387073

  16. Making benefit transfers work

    DEFF Research Database (Denmark)

    Bateman, I. J.; Brouwer, R.; Ferrini, S.;

    2011-01-01

    provides guidance on the appropriate specification of transferable value functions arguing that these should be developed from theoretical rather than ad-hoc statistical principles. These principles are tested via a common format valuation study of water quality improvements across five countries. Results...... support our various hypotheses providing a set of principles for future transfer studies. The application also considers new ways of incorporating distance decay, substitution and framing effects within transfers and presents a novel water quality ladder....

  17. Making benefit transfers work

    DEFF Research Database (Denmark)

    Bateman, I.J.; Brouwer, R.; Ferrini, S.;

    provides guidance on the appropriate specification of transferable value functions arguing that these should be developed from theoretical rather than ad-hoc statistical principles. These principles are tested via a common format valuation study of water quality improvements across five countries. Results...... support our various hypotheses providing a set of principles for future transfer studies. The application also considers new ways of incorporating distance decay, substitution and framing effects within transfers and presents a novel water quality ladder....

  18. Resonance Energy Transfer

    OpenAIRE

    Andrews, David; Bradshaw, David; Dinshaw, Rayomond; Scholes, Gregory

    2015-01-01

    Resonance energy transfer, also known as Förster- or fluorescence- resonance energy transfer, or electronic energy transfer, is a photonic process whose relevance in many major areas of science is reflected both by a wide prevalence of the effect and through numerous technical applications. The process, operating through an optical near-field mechanism, effects a transport of electronic excitation between physically distinct atomic or molecular components, based on transition dipole-dipole co...

  19. A lipid transfer protein that transfers lipid

    OpenAIRE

    Levine, T. P.

    2007-01-01

    Very few lipid transfer proteins (LTPs) have been caught in the act of transferring lipids in vivo from a donor membrane to an acceptor membrane. Now, two studies (Halter, D., S. Neumann, S. M. van Dijk, J. Wolthoorn, A. M. de Maziere, O.V. Vieira, P. Mattjus, J. Klumperman, G. van Meer, and H. Sprong. 2007. J. Cell Biol. 179: 101 115; D'Angelo, G., E. Polishchuk, G. D. Tullio, M. Santoro, A. D. Campli, A. Godi, G. West, J. Bielawski, C.C. Chuang, A. C. van der Spoel, et al. 2007. Nature. 449...

  20. Radial Nerve Tendon Transfers.

    Science.gov (United States)

    Cheah, Andre Eu-Jin; Etcheson, Jennifer; Yao, Jeffrey

    2016-08-01

    Radial nerve palsy typically occurs as a result of trauma or iatrogenic injury and leads to the loss of wrist extension, finger extension, thumb extension, and a reduction in grip strength. In the absence of nerve recovery, reconstruction of motor function involves tendon transfer surgery. The most common donor tendons include the pronator teres, wrist flexors, and finger flexors. The type of tendon transfer is classified based on the donor for the extensor digitorum communis. Good outcomes have been reported for most methods of radial nerve tendon transfers as is typical for positional tendon transfers not requiring significant power. PMID:27387076

  1. Basic heat transfer

    CERN Document Server

    Bacon, D H

    2013-01-01

    Basic Heat Transfer aims to help readers use a computer to solve heat transfer problems and to promote greater understanding by changing data values and observing the effects, which are necessary in design and optimization calculations.The book is concerned with applications including insulation and heating in buildings and pipes, temperature distributions in solids for steady state and transient conditions, the determination of surface heat transfer coefficients for convection in various situations, radiation heat transfer in grey body problems, the use of finned surfaces, and simple heat exc

  2. Coupled transfers; Transferts couples

    Energy Technology Data Exchange (ETDEWEB)

    Nicolas, X.; Lauriat, G.; Jimenez-Rondan, J. [Universite de Marne-la-Vallee, Lab. d' Etudes des Transferts d' Energie et de Matiere (LETEM), 77 (France); Bouali, H.; Mezrhab, A. [Faculte des Sciences, Dept. de Physique, Lab. de Mecanique et Energetique, Oujda (Morocco); Abid, C. [Ecole Polytechnique Universitaire de Marseille, IUSTI UMR 6595, 13 Marseille (France); Stoian, M.; Rebay, M.; Lachi, M.; Padet, J. [Faculte des Sciences, Lab. de Thermomecanique, UTAP, 51 - Reims (France); Mladin, E.C. [Universitaire Polytechnique Bucarest, Faculte de Genie Mecanique, Bucarest (Romania); Mezrhab, A. [Faculte des Sciences, Lab. de Mecanique et Energetique, Dept. de Physique, Oujda (Morocco); Abid, C.; Papini, F. [Ecole Polytechnique, IUSTI, 13 - Marseille (France); Lorrette, C.; Goyheneche, J.M.; Boechat, C.; Pailler, R. [Laboratoire des Composites ThermoStructuraux, UMR 5801, 33 - Pessac (France); Ben Salah, M.; Askri, F.; Jemni, A.; Ben Nasrallah, S. [Ecole Nationale d' Ingenieurs de Monastir, Lab. d' Etudes des Systemes Thermiques et Energetiques (Tunisia); Grine, A.; Desmons, J.Y.; Harmand, S. [Laboratoire de Mecanique et d' Energetique, 59 - Valenciennes (France); Radenac, E.; Gressier, J.; Millan, P. [ONERA, 31 - Toulouse (France); Giovannini, A. [Institut de Mecanique des Fluides de Toulouse, 31 (France)

    2005-07-01

    This session about coupled transfers gathers 30 articles dealing with: numerical study of coupled heat transfers inside an alveolar wall; natural convection/radiant heat transfer coupling inside a plugged and ventilated chimney; finite-volume modeling of the convection-conduction coupling in non-stationary regime; numerical study of the natural convection/radiant heat transfer coupling inside a partitioned cavity; modeling of the thermal conductivity of textile reinforced composites: finite element homogenization on a full periodical pattern; application of the control volume method based on non-structured finite elements to the problems of axisymmetrical radiant heat transfers in any geometries; modeling of convective transfers in transient regime on a flat plate; a conservative method for the non-stationary coupling of aero-thermal engineering codes; measurement of coupled heat transfers (forced convection/radiant transfer) inside an horizontal duct; numerical simulation of the combustion of a water-oil emulsion droplet; numerical simulation study of heat and mass transfers inside a reactor for nano-powders synthesis; reduction of a combustion and heat transfer model of a direct injection diesel engine; modeling of heat transfers inside a knocking operated spark ignition engine; heat loss inside an internal combustion engine, thermodynamical and flamelet model, composition effects of CH{sub 4}H{sub 2} mixtures; experimental study and modeling of the evolution of a flame on a solid fuel; heat transfer for laminar subsonic jet of oxygen plasma impacting an obstacle; hydrogen transport through a A-Si:H layer submitted to an hydrogen plasma: temperature effects; thermal modeling of the CO{sub 2} laser welding of a magnesium alloy; radiant heat transfer inside a 3-D environment: application of the finite volume method in association with the CK model; optimization of the infrared baking of two types of powder paints; optimization of the emission power of an infrared

  3. Technology Transfer and Technology Transfer Intermediaries

    Science.gov (United States)

    Bauer, Stephen M.; Flagg, Jennifer L.

    2010-01-01

    A standard and comprehensive model is needed to evaluate and compare technology transfer systems and the stakeholders within these systems. The principle systems considered include federal laboratories, U.S. universities, the rehabilitation engineering research centers (RERCs), and large small business innovation research programs. An earlier…

  4. Electron transfer in peptides.

    Science.gov (United States)

    Shah, Afzal; Adhikari, Bimalendu; Martic, Sanela; Munir, Azeema; Shahzad, Suniya; Ahmad, Khurshid; Kraatz, Heinz-Bernhard

    2015-02-21

    In this review, we discuss the factors that influence electron transfer in peptides. We summarize experimental results from solution and surface studies and highlight the ongoing debate on the mechanistic aspects of this fundamental reaction. Here, we provide a balanced approach that remains unbiased and does not favor one mechanistic view over another. Support for a putative hopping mechanism in which an electron transfers in a stepwise manner is contrasted with experimental results that support electron tunneling or even some form of ballistic transfer or a pathway transfer for an electron between donor and acceptor sites. In some cases, experimental evidence suggests that a change in the electron transfer mechanism occurs as a result of donor-acceptor separation. However, this common understanding of the switch between tunneling and hopping as a function of chain length is not sufficient for explaining electron transfer in peptides. Apart from chain length, several other factors such as the extent of the secondary structure, backbone conformation, dipole orientation, the presence of special amino acids, hydrogen bonding, and the dynamic properties of a peptide also influence the rate and mode of electron transfer in peptides. Electron transfer plays a key role in physical, chemical and biological systems, so its control is a fundamental task in bioelectrochemical systems, the design of peptide based sensors and molecular junctions. Therefore, this topic is at the heart of a number of biological and technological processes and thus remains of vital interest.

  5. Technology transfer and learning

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2002-01-01

    Despite the fact that international technology transfer has been widely studied its management still encounters many difficulties. To fully understand the issues that are relevant to the process of transferring production technology, it is necessary to determine the important factors that influence

  6. Tendon Transfers for Tetraplegia.

    Science.gov (United States)

    Bednar, Michael S

    2016-08-01

    It is estimated that 65% to 75% of patients with cervical spinal cord injuries could benefit from upper extremity tendon transfer surgery. The goals of surgery are to restore elbow extension, as well as hand pinch, grasp, and release. Patients who have defined goals, actively participate in therapy, and understand expected outcomes, appear to have the highest satisfaction following tendon transfer procedures. PMID:27387082

  7. Transfer Student Characteristics Matter

    Science.gov (United States)

    McGuire, Sharon Paterson; Belcheir, Marcia

    2013-01-01

    The purpose of this study was to identify and define profiles of transfer students and assess if there are different levels of student success (as measured by first semester GPA, retention, and graduation) associated with of those profiles. Using cluster analysis, four transfer student types were identified and labeled as follows: Old Hand at…

  8. Radiative heat transfer

    CERN Document Server

    Modest, Michael F

    2013-01-01

    The third edition of Radiative Heat Transfer describes the basic physics of radiation heat transfer. The book provides models, methodologies, and calculations essential in solving research problems in a variety of industries, including solar and nuclear energy, nanotechnology, biomedical, and environmental. Every chapter of Radiative Heat Transfer offers uncluttered nomenclature, numerous worked examples, and a large number of problems-many based on real world situations-making it ideal for classroom use as well as for self-study. The book's 24 chapters cover the four major areas in the field: surface properties; surface transport; properties of participating media; and transfer through participating media. Within each chapter, all analytical methods are developed in substantial detail, and a number of examples show how the developed relations may be applied to practical problems. It is an extensive solution manual for adopting instructors. Features: most complete text in the field of radiative heat transfer;...

  9. Catalytic and structural features of flavoprotein hydroxylases and epoxidases

    NARCIS (Netherlands)

    Montersino, S.; Tischler, D.; Gassner, G.T.; Berkel, van W.J.H.

    2011-01-01

    Monooxygenases perform chemo-, regio- and/or enantioselective oxygenations of organic substrates under mild reaction conditions. These properties and the increasing number of representatives along with effective preparation methods place monooxygenases in the focus of industrial biocatalysis. Mechan

  10. Fluorescence relaxation spectroscopy: light on dynamical structures of flavoproteins.

    NARCIS (Netherlands)

    Burten-Bastiaens, P.I.H.

    1992-01-01

    Refinements in technique and data analysis have opened new avenues for a detailed interpretation of protein fluorescence. What is more, by combining new insights in protein structure and dynamics with improved knowledge of photophysics of biological chromophores, the coupling between structure-funct

  11. Dexter energy transfer pathways.

    Science.gov (United States)

    Skourtis, Spiros S; Liu, Chaoren; Antoniou, Panayiotis; Virshup, Aaron M; Beratan, David N

    2016-07-19

    Energy transfer with an associated spin change of the donor and acceptor, Dexter energy transfer, is critically important in solar energy harvesting assemblies, damage protection schemes of photobiology, and organometallic opto-electronic materials. Dexter transfer between chemically linked donors and acceptors is bridge mediated, presenting an enticing analogy with bridge-mediated electron and hole transfer. However, Dexter coupling pathways must convey both an electron and a hole from donor to acceptor, and this adds considerable richness to the mediation process. We dissect the bridge-mediated Dexter coupling mechanisms and formulate a theory for triplet energy transfer coupling pathways. Virtual donor-acceptor charge-transfer exciton intermediates dominate at shorter distances or higher tunneling energy gaps, whereas virtual intermediates with an electron and a hole both on the bridge (virtual bridge excitons) dominate for longer distances or lower energy gaps. The effects of virtual bridge excitons were neglected in earlier treatments. The two-particle pathway framework developed here shows how Dexter energy-transfer rates depend on donor, bridge, and acceptor energetics, as well as on orbital symmetry and quantum interference among pathways.

  12. Dexter energy transfer pathways.

    Science.gov (United States)

    Skourtis, Spiros S; Liu, Chaoren; Antoniou, Panayiotis; Virshup, Aaron M; Beratan, David N

    2016-07-19

    Energy transfer with an associated spin change of the donor and acceptor, Dexter energy transfer, is critically important in solar energy harvesting assemblies, damage protection schemes of photobiology, and organometallic opto-electronic materials. Dexter transfer between chemically linked donors and acceptors is bridge mediated, presenting an enticing analogy with bridge-mediated electron and hole transfer. However, Dexter coupling pathways must convey both an electron and a hole from donor to acceptor, and this adds considerable richness to the mediation process. We dissect the bridge-mediated Dexter coupling mechanisms and formulate a theory for triplet energy transfer coupling pathways. Virtual donor-acceptor charge-transfer exciton intermediates dominate at shorter distances or higher tunneling energy gaps, whereas virtual intermediates with an electron and a hole both on the bridge (virtual bridge excitons) dominate for longer distances or lower energy gaps. The effects of virtual bridge excitons were neglected in earlier treatments. The two-particle pathway framework developed here shows how Dexter energy-transfer rates depend on donor, bridge, and acceptor energetics, as well as on orbital symmetry and quantum interference among pathways. PMID:27382185

  13. Technology transfer 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    This document, Technology Transfer 94, is intended to communicate that there are many opportunities available to US industry and academic institutions to work with DOE and its laboratories and facilities in the vital activity of improving technology transfer to meet national needs. It has seven major sections: Introduction, Technology Transfer Activities, Access to Laboratories and Facilities, Laboratories and Facilities, DOE Office, Technologies, and an Index. Technology Transfer Activities highlights DOE`s recent developments in technology transfer and describes plans for the future. Access to Laboratories and Facilities describes the many avenues for cooperative interaction between DOE laboratories or facilities and industry, academia, and other government agencies. Laboratories and Facilities profiles the DOE laboratories and facilities involved in technology transfer and presents information on their missions, programs, expertise, facilities, and equipment, along with data on whom to contact for additional information on technology transfer. DOE Offices summarizes the major research and development programs within DOE. It also contains information on how to access DOE scientific and technical information. Technologies provides descriptions of some of the new technologies developed at DOE laboratories and facilities.

  14. Sequence Classification: 255438 [

    Lifescience Database Archive (English)

    Full Text Available Non-TMB Non-TMH TMB TMB TMB Non-TMB >gi|71906851|ref|YP_284438.1| Electron transfer... flavoprotein beta-subunit:Electron transfer flavoprotein, alpha subunit || http://www.ncbi.nlm.nih.gov/protein/71906851 ...

  15. Sequence Classification: 506139 [

    Lifescience Database Archive (English)

    Full Text Available Non-TMB Non-TMH Non-TMB TMB TMB Non-TMB >gi|73542234|ref|YP_296754.1| Electron tran...sfer flavoprotein beta-subunit:Electron transfer flavoprotein, alpha subunit || http://www.ncbi.nlm.nih.gov/protein/73542234 ...

  16. Sequence Classification: 508394 [

    Lifescience Database Archive (English)

    Full Text Available Non-TMB Non-TMH Non-TMB Non-TMB TMB Non-TMB >gi|73538642|ref|YP_299009.1| Electron ...transfer flavoprotein beta-subunit:Electron transfer flavoprotein, alpha subunit || http://www.ncbi.nlm.nih.gov/protein/73538642 ...

  17. InterProScan Result: FS932423 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS932423 FS932423_2_ORF2 B113B8D416EEAA80 PIR PIRSF000090 Electron transfer flavopr...otein, beta subunit 3.9e-109 T IPR012255 Electron transfer flavoprotein, beta subunit Molecular Function: electron carrier activity (GO:0009055) ...

  18. InterProScan Result: FS827146 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS827146 FS827146_4_ORF1 B113B8D416EEAA80 PIR PIRSF000090 Electron transfer flavopr...otein, beta subunit 3.9e-109 T IPR012255 Electron transfer flavoprotein, beta subunit Molecular Function: electron carrier activity (GO:0009055) ...

  19. NCBI nr-aa BLAST: CBRC-DYAK-01-0032 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-DYAK-01-0032 ref|ZP_01387306.1| Electron transfer flavoprotein beta-subunit [G...eobacter sp. FRC-32] gb|EAT63524.1| Electron transfer flavoprotein beta-subunit [Geobacter sp. FRC-32] ZP_01387306.1 0.077 28% ...

  20. A heat transfer textbook

    CERN Document Server

    Lienhard, John H

    2011-01-01

    This introduction to heat transfer offers advanced undergraduate and graduate engineering students a solid foundation in the subjects of conduction, convection, radiation, and phase-change, in addition to the related topic of mass transfer. A staple of engineering courses around the world for more than three decades, it has been revised and updated regularly by the authors, a pair of recognized experts in the field. The text addresses the implications, limitations, and meanings of many aspects of heat transfer, connecting the subject to its real-world applications and developing students' ins

  1. Versions of transfer conveyors

    Energy Technology Data Exchange (ETDEWEB)

    Goehring, H. (Technische Universitaet, Dresden (German Democratic Republic))

    1990-05-01

    Compares technical specifications of heavy surface mining transfer conveyors built by the manufacturers TAKRAF, O K, Krupp, Buckau-Wolff, Voest-Alpine and others. Equipment is mainly used in brown coal surface mining; its haulage capacity ranges between 600 and 9,300 m{sup 3}/h. Significant specifications of equipment design are considered to be length relation of the two booms for bulk receiving and transfer, as well as total equipment mass. The best length relation has the value 1.1. Further graphs compare the relation of equipment mass, haulage capacity and transfer boom length. Various design advantages of selected equipment series are outlined. 13 refs.

  2. Monte Carlo Radiative Transfer

    CERN Document Server

    Whitney, Barbara A

    2011-01-01

    I outline methods for calculating the solution of Monte Carlo Radiative Transfer (MCRT) in scattering, absorption and emission processes of dust and gas, including polarization. I provide a bibliography of relevant papers on methods with astrophysical applications.

  3. Atmospheric Radiative Transfer

    Science.gov (United States)

    Perliski, Lori

    Because radiative transfer cuts across many scientific disciplines with applications including remote sensing, climate, atmospheric chemistry, and photobiology, there is a need for comprehensive books on this subject that can appeal to a wide readership. While Atmospheric Radiative Transfer takes strides toward filling this niche by addressing a broad range of topics, it is dry reading and suffers from lack of detail. The book was based on a graduate-level course taught at the University of Sciences and Technologies in Lille, France, and indeed, the text reads much like an expanded outline perhaps derived from lecture notes.Part one deals with general radiative transfer, and part two covers Earth's radiation budget, the climate system, and remote sensing techniques. The radiative transfer equation and solutions for absorbing and scattering atmospheres are discussed as are the details of absorption, such as energy levels, line strengths, line intensities, equivalent widths, and weak- and strong-line limits.

  4. Condensation heat transfer

    Science.gov (United States)

    Rose, J. W.

    The paper gives a brief description of some of the better understood aspects of condensation heat transfer and includes discussion of the liquid-vapour interface, natural and forced convection laminar film condensation and dropwise condensation.

  5. Technology transfer for adaptation

    Science.gov (United States)

    Biagini, Bonizella; Kuhl, Laura; Gallagher, Kelly Sims; Ortiz, Claudia

    2014-09-01

    Technology alone will not be able to solve adaptation challenges, but it is likely to play an important role. As a result of the role of technology in adaptation and the importance of international collaboration for climate change, technology transfer for adaptation is a critical but understudied issue. Through an analysis of Global Environment Facility-managed adaptation projects, we find there is significantly more technology transfer occurring in adaptation projects than might be expected given the pessimistic rhetoric surrounding technology transfer for adaptation. Most projects focused on demonstration and early deployment/niche formation for existing technologies rather than earlier stages of innovation, which is understandable considering the pilot nature of the projects. Key challenges for the transfer process, including technology selection and appropriateness under climate change, markets and access to technology, and diffusion strategies are discussed in more detail.

  6. Science transfer for development

    International Nuclear Information System (INIS)

    The author discusses the reasons for science transfer to developing countries. He mentions the impact of science on industrial and technological development in such countries. Furthermore he describes the activities of the IAEA and UNESCO in this field. (HSI).

  7. Multiscale photosynthetic exciton transfer

    CERN Document Server

    Ringsmuth, A K; Stace, T M; 10.1038/nphys2332

    2012-01-01

    Photosynthetic light harvesting provides a natural blueprint for bioengineered and biomimetic solar energy and light detection technologies. Recent evidence suggests some individual light harvesting protein complexes (LHCs) and LHC subunits efficiently transfer excitons towards chemical reaction centers (RCs) via an interplay between excitonic quantum coherence, resonant protein vibrations, and thermal decoherence. The role of coherence in vivo is unclear however, where excitons are transferred through multi-LHC/RC aggregates over distances typically large compared with intra-LHC scales. Here we assess the possibility of long-range coherent transfer in a simple chromophore network with disordered site and transfer coupling energies. Through renormalization we find that, surprisingly, decoherence is diminished at larger scales, and long-range coherence is facilitated by chromophoric clustering. Conversely, static disorder in the site energies grows with length scale, forcing localization. Our results suggest s...

  8. Controlled Environment Specimen Transfer

    DEFF Research Database (Denmark)

    Damsgaard, Christian Danvad; Zandbergen, Henny W.; Hansen, Thomas Willum;

    2014-01-01

    an environmental transmission electron microscope to an in situ X-ray diffractometer through a dedicated transmission electron microscope specimen transfer holder, capable of sealing the specimen in a gaseous environment at elevated temperatures. Two catalyst material systems have been investigated; Cu/ZnO/Al2O3...... transferred in a reactive environment to the environmental transmission electron microscope where further analysis on the local scale were conducted. The Co/Al2O3 catalyst was reduced in the environmental microscope and successfully kept reduced outside the microscope in a reactive environment. The in situ......Specimen transfer under controlled environment conditions, such as temperature, pressure, and gas composition, is necessary to conduct successive complementary in situ characterization of materials sensitive to ambient conditions. The in situ transfer concept is introduced by linking...

  9. Analytical heat transfer

    CERN Document Server

    Han, Je-Chin

    2012-01-01

    … it will complete my library … [and] complement the existing literature on heat transfer. It will be of value for both graduate students and faculty members.-Bengt Sunden, Lund University, Sweden

  10. Convection heat transfer

    CERN Document Server

    Bejan, Adrian

    2013-01-01

    Written by an internationally recognized authority on heat transfer and thermodynamics, this second edition of Convection Heat Transfer contains new and updated problems and examples reflecting real-world research and applications, including heat exchanger design. Teaching not only structure but also technique, the book begins with the simplest problem solving method (scale analysis), and moves on to progressively more advanced and exact methods (integral method, self similarity, asymptotic behavior). A solutions manual is available for all problems and exercises.

  11. Principles of tendon transfers.

    Science.gov (United States)

    Coulet, B

    2016-04-01

    Tendon transfers are carried out to restore functional deficits by rerouting the remaining intact muscles. Transfers are highly attractive in the context of hand surgery because of the possibility of restoring the patient's ability to grip. In palsy cases, tendon transfers are only used when a neurological procedure is contraindicated or has failed. The strategy used to restore function follows a common set of principles, no matter the nature of the deficit. The first step is to clearly distinguish between deficient muscles and muscles that could be transferred. Next, the type of palsy will dictate the scope of the program and the complexity of the gripping movements that can be restored. Based on this reasoning, a surgical strategy that matches the means (transferable muscles) with the objectives (functions to restore) will be established and clearly explained to the patient. Every paralyzed hand can be described using three parameters. 1) Deficient segments: wrist, thumb and long fingers; 2) mechanical performance of muscles groups being revived: high energy-wrist extension and finger flexion that require strong transfers with long excursion; low energy-wrist flexion and finger extension movements that are less demanding mechanically, because they can be accomplished through gravity alone in some cases; 3) condition of the two primary motors in the hand: extrinsics (flexors and extensors) and intrinsics (facilitator). No matter the type of palsy, the transfer surgery follows the same technical principles: exposure, release, fixation, tensioning and rehabilitation. By performing an in-depth analysis of each case and by following strict technical principles, tendon transfer surgery leads to reproducible results; this allows the surgeon to establish clear objectives for the patient preoperatively. PMID:27117119

  12. Principles of Tendon Transfer.

    Science.gov (United States)

    Wilbur, Danielle; Hammert, Warren C

    2016-08-01

    Tendon transfers provide a substitute, either temporary or permanent, when function is lost due to neurologic injury in stroke, cerebral palsy or central nervous system lesions, peripheral nerve injuries, or injuries to the musculotendinous unit itself. This article reviews the basic principles of tendon transfer, which are important when planning surgery and essential for an optimal outcome. In addition, concepts for coapting the tendons during surgery and general principles to be followed during the rehabilitation process are discussed. PMID:27387072

  13. Essays on Intergenerational Transfers

    OpenAIRE

    Fahle, Sean Patrick

    2015-01-01

    The chapters of this dissertation examine transfers between generations across three distinct contexts: a potential role for informal care in U.S. long-term care policy (Chapter 1), the effect of caregiving on bequests (Chapter 2), and making inferences about intra-household allocations using data on intergenerational transfers (Chapter 3).The first chapter poses the question: how can government policy leverage family caregiving to make Medicaid financing of long-term care more sustainable wi...

  14. Theories Supporting Transfer of Training.

    Science.gov (United States)

    Yamnill, Siriporn; McLean, Gary N.

    2001-01-01

    Reviews theories about factors affecting the transfer of training, including theories on motivation (expectancy, equity, goal setting), training transfer design (identical elements, principle, near and far), and transfer climate (organizational). (Contains 36 references.) (SK)

  15. Knowledge transfer isn’t simply transfer

    DEFF Research Database (Denmark)

    Dao, Li; Napier, Nancy

    2012-01-01

    This paper examines micro dynamic aspects of knowledge sharing and learning in international joint venture settings. Learning of expatriate and local managers appears far more complex and mutually dependent than conventionally speculated in existing literature. The paper proposes that the effect...... and outcome of knowledge transfer from joint venture parents and learning in IJVs are dependent on how individual managers (including both expatriate and local) learn, perceive their learning roles, and enact a learning agenda. Empirical evidence is drawn from two cases of international joint ventures between...

  16. Interlingual Transfer in English Learning

    Institute of Scientific and Technical Information of China (English)

    王晓娜

    2016-01-01

    Interlingual transfer refers to transfer rules from the first language. There are many differences between English and Chinese, which will unavoidably interfere with the English learning. When the interference of mother tongue fosters target language learning, it is called mother tongue’s positive transfer. Conversely, the mother tongue’s negative transfer will emerge. With mother tongue mode of thinking automatically, Chinese students always make errors when they compose a sentence or write a passage. Interlingual transfer includes three aspects: lexical transfer, grammatical transfer and cultural transfer.

  17. Transfer to animals

    International Nuclear Information System (INIS)

    Data have been compiled to derive animal product transfer coefficients for radionuclides to update the values given in Technical Reports Series No. 364. Significant new data inputs have been incorporated from an extensive review of Russian language information and inclusion of data published since the early 1990s. The resultant database has been used to provide reference transfer coefficient values for a range of radionuclides to (i) cow, sheep and goat milk, (ii) meat (muscle) of cattle, sheep, goats, pigs and poultry and (iii) eggs. The approaches and procedures used to identify and collate data, and assumptions used are given. For most animal products, transfer coefficient values for elements additional to those in Technical Reports Series No. 364 are provided, although some elements were considered in the earlier evaluation which were not included in this review. Differences between the Technical Reports Series No. 364 'expected' values and the reference values from this document, which will be incorporated into the revised transfer parameter handbook, are discussed. An alternative approach to quantifying transfer by using concentration ratios is evaluated and CR values which could be applied across animal species have been provided for milk and meat. Information on fractional gastrointestinal absorption in adult ruminants has been compiled and reference values presented. Despite these improvements many data gaps remain. (author)

  18. Heat and mass transfer

    CERN Document Server

    Baehr, Hans Dieter

    2011-01-01

    This comprehensive textbook provides a solid foundation of knowledge on the principles of heat and mass transfer and shows how to solve problems by applying modern methods. The basic theory is developed systematically, exploring in detail the solution methods to all important problems.   The thoroughly revised 3rd edition includes an introduction to the numerical solution of Finite Elements. A new section on heat and mass transfer in porous media has also been added.   The book will be useful not only to upper-level and graduate students, but also to practicing scientists and engineers, offering a firm understanding of the principles of heat and mass transfer, and showing how to solve problems by applying modern methods. Many completed examples and numerous exercises with solutions facilitate learning and understanding, and an appendix includes data on key properties of important substances.

  19. Tech transfer outreach

    Energy Technology Data Exchange (ETDEWEB)

    Liebetrau, S. (ed.)

    1992-01-01

    This document provides an informal summary of the conference workshop sessions. Tech Transfer Outreach '' was originally designed as an opportunity for national laboratory communications and technology transfer staff to become better acquainted and to discuss matters of mutual interest. When DOE field office personnel asked if they could attend, and then when one of our keynote speakers became a participant in the discussions, the actual event grew in importance. The conference participants--the laboratories and DOE representatives from across the nation--worked to brainstorm ideas. Their objective: identify ways to cooperate for effective (and cost-effective) technology transfer outreach. Thus, this proceedings is truly a product of ten national laboratories and DOE, working together. It candidly presents the discussion of issues and the ideas generated by each working group. The issues and recommendations are a consensus of their views.

  20. Diffusion and mass transfer

    CERN Document Server

    Vrentas, James S

    2013-01-01

    The book first covers the five elements necessary to formulate and solve mass transfer problems, that is, conservation laws and field equations, boundary conditions, constitutive equations, parameters in constitutive equations, and mathematical methods that can be used to solve the partial differential equations commonly encountered in mass transfer problems. Jump balances, Green’s function solution methods, and the free-volume theory for the prediction of self-diffusion coefficients for polymer–solvent systems are among the topics covered. The authors then use those elements to analyze a wide variety of mass transfer problems, including bubble dissolution, polymer sorption and desorption, dispersion, impurity migration in plastic containers, and utilization of polymers in drug delivery. The text offers detailed solutions, along with some theoretical aspects, for numerous processes including viscoelastic diffusion, moving boundary problems, diffusion and reaction, membrane transport, wave behavior, sedime...

  1. Neutron signal transfer analysis

    CERN Document Server

    Pleinert, H; Lehmann, E

    1999-01-01

    A new method called neutron signal transfer analysis has been developed for quantitative determination of hydrogenous distributions from neutron radiographic measurements. The technique is based on a model which describes the detector signal obtained in the measurement as a result of the action of three different mechanisms expressed by signal transfer functions. The explicit forms of the signal transfer functions are determined by Monte Carlo computer simulations and contain only the distribution as a variable. Therefore an unknown distribution can be determined from the detector signal by recursive iteration. This technique provides a simple and efficient tool for analysis of this type while also taking into account complex effects due to the energy dependency of neutron interaction and single and multiple scattering. Therefore this method provides an efficient tool for precise quantitative analysis using neutron radiography, as for example quantitative determination of moisture distributions in porous buil...

  2. Thermal radiation heat transfer

    CERN Document Server

    Howell, John R; Mengüç, M Pinar

    2011-01-01

    Providing a comprehensive overview of the radiative behavior and properties of materials, the fifth edition of this classic textbook describes the physics of radiative heat transfer, development of relevant analysis methods, and associated mathematical and numerical techniques. Retaining the salient features and fundamental coverage that have made it popular, Thermal Radiation Heat Transfer, Fifth Edition has been carefully streamlined to omit superfluous material, yet enhanced to update information with extensive references. Includes four new chapters on Inverse Methods, Electromagnetic Theory, Scattering and Absorption by Particles, and Near-Field Radiative Transfer Keeping pace with significant developments, this book begins by addressing the radiative properties of blackbody and opaque materials, and how they are predicted using electromagnetic theory and obtained through measurements. It discusses radiative exchange in enclosures without any radiating medium between the surfaces-and where heat conduction...

  3. Orbital Fluid Transfer System

    Science.gov (United States)

    Johnston, A. S., (Nick); Ryder, Mel; Tyler, Tony R.

    1998-01-01

    An automated fluid and power interface system needs to be developed for future space missions which require on orbit consumable replenishment. Current method of fluid transfer require manned vehicles and extravehicular activity. Currently the US does not have an automated capability for consumable transfer on-orbit. This technology would benefit both Space Station and long duration satellites. In order to provide this technology the Automated Fluid Interface System (AFIS) was developed. The AFIS project was an advanced development program aimed at developing a prototype satellite servicer for future space operations. This mechanism could transfer propellants, cryogens, fluids, gasses, electrical power, and communications from a tanker unit to the orbiting satellite. The development of this unit was a cooperative effort between Marshall Space Flight Center in Huntsville, Alabama, and Moog, Inc. in East Aurora, New York. An engineering model was built and underwent substantial development testing at Marshall Space Flight Center (MSFC). While the AFIS is not suitable for spaceflight, testing and evaluation of the AFIS provided significant experience which would be beneficial in building a flight unit. The lessons learned from testing the AFIS provided the foundation for the next generation fluid transfer mechanism, the Orbital Fluid Transfer System (OFTS). The OFTS project was a study contract with MSFC and Moog, Inc. The OFTS was designed for the International Space Station (ISS), but its flexible design could used for long duration satellite missions and other applications. The OFTS was designed to be used after docking. The primary function was to transfer bipropellants and high pressure gases. The other items addressed by this task included propellant storage, hardware integration, safety and control system issues. A new concept for high pressure couplings was also developed. The results of the AFIS testing provided an excellent basis for the OFTS design. The OFTS

  4. Elementary heat transfer analysis

    CERN Document Server

    Whitaker, Stephen; Hartnett, James P

    1976-01-01

    Elementary Heat Transfer Analysis provides information pertinent to the fundamental aspects of the nature of transient heat conduction. This book presents a thorough understanding of the thermal energy equation and its application to boundary layer flows and confined and unconfined turbulent flows. Organized into nine chapters, this book begins with an overview of the use of heat transfer coefficients in formulating the flux condition at phase interface. This text then explains the specification as well as application of flux boundary conditions. Other chapters consider a derivation of the tra

  5. Beyond unidirectional knowledge transfer

    DEFF Research Database (Denmark)

    Ulhøi, John Parm; Neergaard, Helle; Bjerregaard, Toke

    2012-01-01

    Using theory on technology transfer and on trust and an indepth study of nine university departments and nineteen science-based small and medium-sized enterprises (SMEs), the authors explore the nature and direction of knowledge flows during university-industry R&D collaboration. More specifically......, they examine the nature and direction of R&D technological knowledge transfer in collaborations between universities and science-based SMEs and the primary mechanisms regulating such collaborations. The findings suggest that these collaborations are highly recursive processes of technological knowledge...

  6. Transfer technologii a gospodarka

    OpenAIRE

    Mączyński, Jacek

    2005-01-01

    Transfer technologii jest obecnie kluczem do konkurencyjności i rozwoju ekonomicznego państw. Już wiele lat temu tacy ekonomiści, jak Robert Solow i Joseph Schumpeter, uznali inwestowanie w nowe technologie i ich upowszechnianie za siłę napędową wzrostu gospodarczego. Transfer technologii wpływa na tempo i kierunki rozwoju gospodarczego, strukturę gospodarki, a także na powstawanie jej nowych gałęzi, w tym wysoko zaawansowanych technologicznie. Rynek technologii tworzy nowe formy walki konkur...

  7. Transferences of Purkinje systems

    Directory of Open Access Journals (Sweden)

    W. F. Harris

    2011-12-01

    Full Text Available The transferences of heterocentric astigmatic Purkinje systems are special: submatrices B and C, that is, the disjugacy and the divergence of the system, are symmetric and submatrix D (the divarication is the transpose of submatrix A (the dilation.  It is the primary purpose of this paper to provide a proof.  The paper also derives other relationships among the fundamental properties and compact expressions for the transference and optical axis locator of a Purkinje system. (S Afr Optom 2011 70(2 57-60

  8. Knowledge Transfers following Acquisition

    DEFF Research Database (Denmark)

    Gammelgaard, Jens

    2001-01-01

    Prior relations between the acquiring firm and the target company pave the way for knowledge transfers subsequent to the acquisitions. One major reason is that through the market-based relations the two actors build up mutual trust and simultaneously they learn how to communicate. An empirical...... study of 54 Danish acquisitions taking place abroad from 1994 to 1998 demonstrated that when there was a high level of trust between the acquiring firm and the target firm before the take-over, then medium and strong tie-binding knowledge transfer mechanisms, such as project groups and job rotation...

  9. Heat transfer fluids containing nanoparticles

    Science.gov (United States)

    Singh, Dileep; Routbort, Jules; Routbort, A.J.; Yu, Wenhua; Timofeeva, Elena; Smith, David S.; France, David M.

    2016-05-17

    A nanofluid of a base heat transfer fluid and a plurality of ceramic nanoparticles suspended throughout the base heat transfer fluid applicable to commercial and industrial heat transfer applications. The nanofluid is stable, non-reactive and exhibits enhanced heat transfer properties relative to the base heat transfer fluid, with only minimal increases in pumping power required relative to the base heat transfer fluid. In a particular embodiment, the plurality of ceramic nanoparticles comprise silicon carbide and the base heat transfer fluid comprises water and water and ethylene glycol mixtures.

  10. Solar Energy: Heat Transfer.

    Science.gov (United States)

    Knapp, Henry H., III

    This module on heat transfer is one of six in a series intended for use as supplements to currently available materials on solar energy and energy conservation. Together with the recommended texts and references (sources are identified), these modules provide an effective introduction to energy conservation and solar energy technologies. The…

  11. Transfer metrics analytics project

    CERN Document Server

    Matonis, Zygimantas

    2016-01-01

    This report represents work done towards predicting transfer rates/latencies on Worldwide LHC Computing Grid (WLCG) sites using Machine Learning techniques. Topic covered are technologies used for the project, data preparation for ML suitable format and attribute selection as well as a comparison of different ML algorithms.

  12. Knowledge Transfers in IJVs

    DEFF Research Database (Denmark)

    Park, Chansoo; Vertinsky, Ilan; Minbaeva, Dana

    firms to their international joint ventures (IJVs) in South Korea. We developed a theoretical model that examines the impacts of the knowledge senders¡¯ disseminative capacities on knowledge transfer to IJVs. We tested our theory with data from 199 IJVs in South Korea. We found that the willingness...

  13. Electron transfer in proteins

    DEFF Research Database (Denmark)

    Farver, O; Pecht, I

    1991-01-01

    Electron migration between and within proteins is one of the most prevalent forms of biological energy conversion processes. Electron transfer reactions take place between active centers such as transition metal ions or organic cofactors over considerable distances at fast rates and with remarkab...

  14. Knowledge Management and Transfer

    Energy Technology Data Exchange (ETDEWEB)

    Sennanye, D.M.; Thugwane, S.J.; Rasweswe, M.A. [South African Young Nuclear Professionals Society, South African Nuclear Energy Cooperation, National Nuclear Regulator, P O Box 7106, Centurion 0046 (South Africa)

    2008-07-01

    Knowledge management has become an important concept in the nuclear industry globally. This has been driven by the fact that new reactors are commissioned and some are decommissioned. Since most old experts are near retirement then there is a need to capture the nuclear knowledge and expertise and transfer it to the new generation. Knowledge transfer is one of the important building blocks of knowledge management. Processes and strategies need to be developed in order to transfer this knowledge. South African Young Nuclear Professionals Society (SAYNPS) has established a document to address strategies that can be used to close the knowledge gap between the young less experienced and experts in the field. This action will help the young generation to participate in knowledge management. The major challenges will be the willingness of the experts to share and making sure that all knowledge is captured, stored and kept up to date. The paper presents the SAYNPS point of view with regard to knowledge transfer. (authors)

  15. Catalysis: Quantifying charge transfer

    Science.gov (United States)

    James, Trevor E.; Campbell, Charles T.

    2016-02-01

    Improving the design of catalytic materials for clean energy production requires a better understanding of their electronic properties, which remains experimentally challenging. Researchers now quantify the number of electrons transferred from metal nanoparticles to an oxide support as a function of particle size.

  16. Knowledge Management and Transfer

    International Nuclear Information System (INIS)

    Knowledge management has become an important concept in the nuclear industry globally. This has been driven by the fact that new reactors are commissioned and some are decommissioned. Since most old experts are near retirement then there is a need to capture the nuclear knowledge and expertise and transfer it to the new generation. Knowledge transfer is one of the important building blocks of knowledge management. Processes and strategies need to be developed in order to transfer this knowledge. South African Young Nuclear Professionals Society (SAYNPS) has established a document to address strategies that can be used to close the knowledge gap between the young less experienced and experts in the field. This action will help the young generation to participate in knowledge management. The major challenges will be the willingness of the experts to share and making sure that all knowledge is captured, stored and kept up to date. The paper presents the SAYNPS point of view with regard to knowledge transfer. (authors)

  17. Transfer of manufacturing units

    DEFF Research Database (Denmark)

    Madsen, Erik Skov; Riis, Jens Ove; Sørensen, Brian Vejrum

    2008-01-01

    The ongoing and unfolding relocation of activities is one of the major trends, that calls for attention in the domain of operations management. In particular, prescriptive models outlining: stages of the process, where to locate, and how to establish the new facilities have been studied, while th...... and dilemmas to be addressed when transferring manufacturing units....

  18. Supervised Transfer Sparse Coding

    KAUST Repository

    Al-Shedivat, Maruan

    2014-07-27

    A combination of the sparse coding and transfer learn- ing techniques was shown to be accurate and robust in classification tasks where training and testing objects have a shared feature space but are sampled from differ- ent underlying distributions, i.e., belong to different do- mains. The key assumption in such case is that in spite of the domain disparity, samples from different domains share some common hidden factors. Previous methods often assumed that all the objects in the target domain are unlabeled, and thus the training set solely comprised objects from the source domain. However, in real world applications, the target domain often has some labeled objects, or one can always manually label a small num- ber of them. In this paper, we explore such possibil- ity and show how a small number of labeled data in the target domain can significantly leverage classifica- tion accuracy of the state-of-the-art transfer sparse cod- ing methods. We further propose a unified framework named supervised transfer sparse coding (STSC) which simultaneously optimizes sparse representation, domain transfer and classification. Experimental results on three applications demonstrate that a little manual labeling and then learning the model in a supervised fashion can significantly improve classification accuracy.

  19. Transfer Pricing Principles

    DEFF Research Database (Denmark)

    Jensen, Dennis Ramsdahl

    Konferencebidraget indeholder en kritisk analyse af transfer pricing reglerne på henholdsvis moms og indkomstskatterettens område med henblik på en diskussion af, det er hensigtsmæssigt med en harmonisering af reglerne på tværs af de to retsområder...

  20. Feed tank transfer requirements

    International Nuclear Information System (INIS)

    This document presents a definition of tank turnover; DOE responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements; records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor for use during Phase 1B

  1. Symbolic local information transfer

    Science.gov (United States)

    Nakajima, K.; Haruna, T.

    2013-06-01

    Recently, the permutation-information theoretic approach has been used in a broad range of research fields. In particular, in the study of high-dimensional dynamical systems, it has been shown that this approach can be effective in characterizing global properties, including the complexity of their spatiotemporal dynamics. Here, we show that this approach can also be applied to reveal local spatiotemporal profiles of distributed computations existing at each spatiotemporal point in the system. J. T. Lizier et al. have recently introduced the concept of local information dynamics, which consists of information storage, transfer, and modification. This concept has been intensively studied with regard to cellular automata, and has provided quantitative evidence of several characteristic behaviors observed in the system. In this paper, by focusing on the local information transfer, we demonstrate that the application of the permutation-information theoretic approach, which introduces natural symbolization methods, makes the concept easily extendible to systems that have continuous states. We propose measures called symbolic local transfer entropies, and apply these measures to two test models, the coupled map lattice (CML) system and the Bak-Sneppen model (BS-model), to show their relevance to spatiotemporal systems that have continuous states. In the CML, we demonstrate that it can be successfully used as a spatiotemporal filter to stress a coherent structure buried in the system. In particular, we show that the approach can clearly stress out defect turbulences or Brownian motion of defects from the background, which gives quantitative evidence suggesting that these moving patterns are the information transfer substrate in the spatiotemporal system. We then show that these measures reveal qualitatively different properties from the conventional approach using the sliding window method, and are also robust against external noise. In the BS-model, we demonstrate that

  2. ETFDH mutations as a major cause of riboflavin-responsive multiple acyl-CoA dehydrogenation deficiency

    DEFF Research Database (Denmark)

    Olsen, Rikke K J; Olpin, Simon E; Andresen, Brage S;

    2007-01-01

    Multiple acyl-CoA dehydrogenation deficiency (MADD) is a disorder of fatty acid, amino acid and choline metabolism that can result from defects in two flavoproteins, electron transfer flavoprotein (ETF) or ETF: ubiquinone oxidoreductase (ETF:QO). Some patients respond to pharmacological doses...

  3. Multiscale conformal pattern transfer

    Science.gov (United States)

    Lodewijks, Kristof; Miljkovic, Vladimir; Massiot, Inès; Mekonnen, Addis; Verre, Ruggero; Olsson, Eva; Dmitriev, Alexandre

    2016-06-01

    We demonstrate a method for seamless transfer from a parent flat substrate of basically any lithographic top-down or bottom-up pattern onto essentially any kind of surface. The nano- or microscale patterns, spanning macroscopic surface areas, can be transferred with high conformity onto a large variety of surfaces when such patterns are produced on a thin carbon film, grown on top of a sacrificial layer. The latter allows lifting the patterns from the flat parent substrate onto a water-air interface to be picked up by the host surface of choice. We illustrate the power of this technique by functionalizing broad range of materials including glass, plastics, metals, rough semiconductors and polymers, highlighting the potential applications in in situ colorimetry of the chemistry of materials, anti-counterfeit technologies, biomolecular and biomedical studies, light-matter interactions at the nanoscale, conformal photovoltaics and flexible electronics.

  4. Wireless power transfer system

    Science.gov (United States)

    Wu, Hunter; Sealy, Kylee; Gilchrist, Aaron

    2016-02-23

    A system includes a first stage of an inductive power transfer system with an LCL load resonant converter with a switching section, an LCL tuning circuit, and a primary receiver pad. The IPT system includes a second stage with a secondary receiver pad, a secondary resonant circuit, a secondary rectification circuit, and a secondary decoupling converter. The secondary receiver pad connects to the secondary resonant circuit. The secondary resonant circuit connects to the secondary rectification circuit. The secondary rectification circuit connects to the secondary decoupling converter. The second stage connects to a load. The load includes an energy storage element. The second stage and load are located on a vehicle and the first stage is located at a fixed location. The primary receiver pad wirelessly transfers power to the secondary receiver pad across a gap when the vehicle positions the secondary receiver pad with respect to the primary receiver pad.

  5. Transfers to freshwater biota

    International Nuclear Information System (INIS)

    It remains important to monitor the fate of radionuclides, particularly in environmental compartments that comprise human pathways. Therefore, an extensive literature survey has been conducted to compile available data on the transfer of radionuclides and their analogues to edible freshwater biota. Focus was placed on compilation of steady state transfer parameters for two freshwater pathways, including water-to-biota and sediment-to-biota. In general, although in many cases, extensive data were available for fishes and invertebrates, relatively fewer data were available for freshwater primary producers, amphibians and reptiles. To fill in these gaps, data were also compiled on the internal partitioning of elements in the body with respect to tissue masses, which could be used to estimate radionuclide concentrations between compartments in the body. (author)

  6. Heat Transfer Analogies

    International Nuclear Information System (INIS)

    This report contains descriptions of various analogues utilised to study different steady-state and unsteady-state heat transfer problems. The analogues covered are as follows: 1 . Hydraulic: a) water flow b) air flow 2. Membrane 3. Geometric Electrical: a) Electrolytic-tank b) Conducting sheet 4. Network; a) Resistance b) R-C A comparison of the different analogues is presented in the form of a table

  7. Feed tank transfer requirements

    Energy Technology Data Exchange (ETDEWEB)

    Freeman-Pollard, J.R.

    1998-09-16

    This document presents a definition of tank turnover. Also, DOE and PC responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements are presented for two cases (i.e., tank modifications occurring before tank turnover and tank modification occurring after tank turnover). Finally, records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor are presented.

  8. Technology transfer for development

    International Nuclear Information System (INIS)

    The IAEA has developed a multifaceted approach to ensure that assistance to Member States results in assured technology transfer. Through advice and planning, the IAEA helps to assess the costs and benefits of a given technology, determine the basic requirements for its efficient use in conditions specific to the country, and prepare a plan for its introduction. This report describes in brief the Technical Co-operation Programmes

  9. Feed tank transfer requirements

    International Nuclear Information System (INIS)

    This document presents a definition of tank turnover. Also, DOE and PC responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements are presented for two cases (i.e., tank modifications occurring before tank turnover and tank modification occurring after tank turnover). Finally, records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor are presented

  10. Multinucleon transfer reactions

    International Nuclear Information System (INIS)

    Nuclear reactions induced by complex nuclei are studied. The description of the single neutron transfer is used to show some aspect of the theoretical treatment of transfer reactions and rules concerning the dependence of cross sections on quantum numbers of the initial and final channels are deduced. Strongly excited states of 20Ne, 19F, sup(16,17)0, 15N were studied experimentally by using different projectile-target combinations in the four-particle, eight-particle and ten-particle transfer reactions, leading to the some final nuclei. Obtained results are discussed. In addition, studies of the projectile break-up phenomenon were performed. The dissociation of 6Li and 7Li projectiles was investigated in reactions on Pb, Sn and Ni nuclei. These nuclei were chosen to allow measurements at one incident energy below, above and at the Coulomb barrier. The observed spectra indicate that the process proceeds primarily via the resonance level but the shape deviates from the shape which was calculated assuming isotropic decay of the excited 6Li in its center of mass system. The investigations of the elastic scattering turned out to be more fruitful and allowed to define better the Coulomb barrier for the 6Li-target system. (S.B.)

  11. The argument from transfer.

    Science.gov (United States)

    Munthe, Christian

    1996-01-01

    Utilitarian arguments on bioethical issues regarding human reproduction typically start with the view that it is wrong, other things being equal, not to procreate when this would have resulted in an additional being with a life worth living. The paper takes this view for granted and examines the common utilitarian claim that overpopulation and destitution in the world mean that, in practice, this obligation to procreate, other things being equal, often turns into a (categorical) obligation not to procreate. A version of this argument is defended -- a version called the argument from transfer -- according to which, rather than having additional children and care for them in order to make them happy, many people in the West ought to abstain from procreation and take care of destitute children already existing. The reasoning leading up to this conclusion raises some philosophical questions, seldom discussed in connection with bioethics, which indicate that the argument from transfer, although supporting the claim above, cannot neutralise the obligation to create more happy people as easily as assumed by utilitarians. It is argued that the argument from transfer may place many people facing the choice of procreation in a peculiar moral dilemma.

  12. What Is Technology Transfer? | Poster

    Science.gov (United States)

    The NCI Technology Transfer Center (TTC) facilitates partnerships between NIH research laboratories and external partners. With a team of technology transfer specialists, NCI TTC guides interactions from discovery to patenting, as well as from collaboration and invention development to licensing.

  13. Technology transfer in CANDU marketing

    International Nuclear Information System (INIS)

    The author discusses how the CANDU system lends itself to technology transfer, the scope of CANDU technology transfer, and the benefits and problems associated with technology transfer. The establishment of joint ventures between supplier and client nations offers benefits to both parties. Canada can offer varying technology transfer packages, each tailored to a client nation's needs and capabilities. Such a package could include all the hardware and software necessary to develop a self-sufficient nuclear infrastructure in the client nation

  14. Teaching Mathematics Understandings for Transfer

    Science.gov (United States)

    Jones, Jennifer L.; Jones, Karrie A.; Vermette, Paul J.

    2009-01-01

    Promoting student understanding for transfer is an illusive hallmark of effective mathematics instruction. While much research has shown the necessity of promoting understanding for transfer, less attention has been paid to actual pedagogical strategies that can be used to promote transfer of mathematical ideas. Using Fogarty et al. (1992, "How to…

  15. Mass Transfer with Chemical Reaction.

    Science.gov (United States)

    DeCoursey, W. J.

    1987-01-01

    Describes the organization of a graduate course dealing with mass transfer, particularly as it relates to chemical reactions. Discusses the course outline, including mathematics models of mass transfer, enhancement of mass transfer rates by homogeneous chemical reaction, and gas-liquid systems with chemical reaction. (TW)

  16. Student Transfer Matrix, Fall 1996.

    Science.gov (United States)

    Oklahoma State Regents for Higher Education, Oklahoma City.

    The Student Transfer Matrix provides data on the numbers of students transferring from Oklahoma public and private institutions of higher education to other Oklahoma institutions, using data from receiving institutions. Among the highlights are: the number of students who transferred to four-year and two-year institutions remained steady at 57.8…

  17. 76 FR 73993 - Remittance Transfers

    Science.gov (United States)

    2011-11-30

    ... resolution, and provides a detailed analysis of the services offered by remittance transfer providers. 99 FR... money transfer instruments in paragraph (a). The Board also amended paragraph (b) to remove the language... funds transfers was simply to remove redundant language and has no substantive effect. III. Final...

  18. Large molten pool heat transfer

    International Nuclear Information System (INIS)

    This workshop on large molten pool heat transfer is composed of 5 sessions which titles are: feasibility of in-vessel core debris cooling; experiments on molten pool heat transfer; calculational efforts on molten pool convection; heat transfer to the surrounding water, experimental techniques; future experiments and ex-vessel studies (RASPLAV, TOLBIAC, BALI, SULTAN, CORVIS, VULCANO, CORINE programs)

  19. Electron transfer reactions in the NADPH oxidase system of neutrophils--involvement of an NADPH-cytochrome c reductase in the oxidase system.

    Science.gov (United States)

    Fujii, H; Kakinuma, K

    1991-11-12

    Membrane-bound NADPH oxidase of pig blood neutrophils was solubilized with heptylthioglucoside in a high yield. The solubilized preparation from myristate-stimulated cells (sample S) showed high O2- generating activity, and the preparation from resting cells (sample R) had no activity, but the two samples had equal amounts of flavins and cytochrome b-558 (cyt b-558). The electron transfer reactions to exogenous cytochrome c (cyt c) or cyt b-558 in samples S and R were examined. Under anaerobic conditions, NADPH-dependent cyt c reductase activity appeared higher in sample S than in sample R, and the addition of FMN and FAD greatly enhanced the reductase activity of sample S, but not that of sample R. No marked difference between the reductase activities of samples S and R was seen with NADH. Photoreduction of the NADPH oxidase system was examined in the absence of NADPH under anaerobic conditions by monitoring the reduction rates of exogenous cyt c using a flashlight with cut-off filters between 400 and 500 nm. Cyt c reduction was much higher in sample S than in sample R on photoexcitation at about 450 nm. Photoreduction was carried out with a band-pass filter for selective irradiation at 450 nm. Marked reduction of exogenous cyt c was observed only in sample S: the small reduction of cyt c by sample R was independent of the light wavelength and was equal to the blank level. In contrast, no difference in the reduction of cyt b-558 by the two samples was found by either NADPH or photoreduction. Under aerobic conditions, no direct reduction of either cyt c or cyt b-558 was observed. These results suggest that an NADPH-cyt c reductase (a membrane-bound flavoprotein) is involved in the NADPH oxidase system of stimulated neutrophils. PMID:1659905

  20. Enabling cleanup technology transfer

    International Nuclear Information System (INIS)

    Technology transfer in the environmental restoration, or cleanup, area has been challenging. While there is little doubt that innovative technologies are needed to reduce the times, risks, and costs associated with the cleanup of federal sites, particularly those of the Departments of Energy (DOE) and Defense, the use of such technologies in actual cleanups has been relatively limited. There are, of course, many reasons why technologies do not reach the implementation phase or do not get transferred from developing entities to the user community. For example, many past cleanup contracts provided few incentives for performance that would compel a contractor to seek improvement via technology applications. While performance-based contracts are becoming more common, they alone will not drive increased technology applications. This paper focuses on some applications of cleanup methodologies and technologies that have been successful and are illustrative of a more general principle. The principle is at once obvious and not widely practiced. It is that, with few exceptions, innovative cleanup technologies are rarely implemented successfully alone but rather are implemented in the context of enabling processes and methodologies. And, since cleanup is conducted in a regulatory environment, the stage is better set for technology transfer when the context includes substantive interactions with the relevant stakeholders. Examples of this principle are drawn from Argonne National Laboratory's experiences in Adaptive Sampling and Analysis Programs (ASAPs), Precise Excavation, and the DOE Technology Connection (TechCon) Program. The lessons learned may be applicable to the continuing challenges posed by the cleanup and long-term stewardship of radioactive contaminants and unexploded ordnance (UXO) at federal sites

  1. Posterior Tibial Tendon Transfer.

    Science.gov (United States)

    Shane, Amber M; Reeves, Christopher L; Cameron, Jordan D; Vazales, Ryan

    2016-01-01

    When performed correctly with the right patient population, a tibialis posterior muscle/tendon transfer is an effective procedure. Many different methods have been established for fixating the tendon, each of which has its' own indications. Passing through the interosseous membrane is the preferred and recommended method and should be used unless this is not possible. Good surgical planning based on patient needs and expectations, along with excellent postoperative care including early range of motion and physical therapy minimizes risk of complications and allows for the optimal outcome to be achieved. PMID:26590722

  2. Lipid-transfer proteins.

    Science.gov (United States)

    Ng, Tzi Bun; Cheung, Randy Chi Fai; Wong, Jack Ho; Ye, Xiujuan

    2012-01-01

    Lipid-transfer proteins (LTPs) are basic proteins found in abundance in higher plants. LTPs play lots of roles in plants such as participation in cutin formation, embryogenesis, defense reactions against phytopathogens, symbiosis, and the adaptation of plants to various environmental conditions. In addition, LTPs from field mustard and Chinese daffodil exhibit antiproliferative activity against human cancer cells. LTPs from chili pepper and coffee manifest inhibitory activity against fungi pathogenic to humans such as Candida species. The intent of this article is to review LTPs in the plant kingdom. PMID:23193591

  3. Advances in electron transfer chemistry

    CERN Document Server

    Mariano, Patrick S

    1993-01-01

    Advances in Electron Transfer Chemistry, Volume 3 presents studies that discuss findings in the various aspects of electron chemistry. The book is comprised of four chapters; each chapter reviews a work that tackles an issue in electron transfer chemistry. Chapter 1 discusses the photoinduced electron transfer in flexible biaryl donor-acceptor molecules. Chapter 2 tackles light-induced electron transfer in inorganic systems in homogeneous and heterogeneous phases. The book also covers internal geometry relaxation effects on electron transfer rates of amino-centered systems. The sequential elec

  4. Measuring of heat transfer coefficient

    DEFF Research Database (Denmark)

    Henningsen, Poul; Lindegren, Maria

    Subtask 3.4 Measuring of heat transfer coefficient Subtask 3.4.1 Design and setting up of tests to measure heat transfer coefficient Objective: Complementary testing methods together with the relevant experimental equipment are to be designed by the two partners involved in order to measure...... the heat transfer coefficient for a wide range of interface conditions in hot and warm forging processes. Subtask 3.4.2 Measurement of heat transfer coefficient The objective of subtask 3.4.2 is to determine heat transfer values for different interface conditions reflecting those typically operating in hot...

  5. aerodynamics and heat transfer

    Directory of Open Access Journals (Sweden)

    J. N. Rajadas

    1998-01-01

    Full Text Available A multidisciplinary optimization procedure, with the integration of aerodynamic and heat transfer criteria, has been developed for the design of gas turbine blades. Two different optimization formulations have been used. In the first formulation, the maximum temperature in the blade section is chosen as the objective function to be minimized. An upper bound constraint is imposed on the blade average temperature and a lower bound constraint is imposed on the blade tangential force coefficient. In the second formulation, the blade average and maximum temperatures are chosen as objective functions. In both formulations, bounds are imposed on the velocity gradients at several points along the surface of the airfoil to eliminate leading edge velocity spikes which deteriorate aerodynamic performance. Shape optimization is performed using the blade external and coolant path geometric parameters as design variables. Aerodynamic analysis is performed using a panel code. Heat transfer analysis is performed using the finite element method. A gradient based procedure in conjunction with an approximate analysis technique is used for optimization. The results obtained using both optimization techniques are compared with a reference geometry. Both techniques yield significant improvements with the multiobjective formulation resulting in slightly superior design.

  6. Dams and Intergovernmental Transfers

    Science.gov (United States)

    Bao, X.

    2012-12-01

    Gainers and Losers are always associated with large scale hydrological infrastructure construction, such as dams, canals and water treatment facilities. Since most of these projects are public services and public goods, Some of these uneven impacts cannot fully be solved by markets. This paper tried to explore whether the governments are paying any effort to balance the uneven distributional impacts caused by dam construction or not. It showed that dam construction brought an average 2% decrease in per capita tax revenue in the upstream counties, a 30% increase in the dam-location counties and an insignificant increase in downstream counties. Similar distributional impacts were observed for other outcome variables. like rural income and agricultural crop yields, though the impacts differ across different crops. The paper also found some balancing efforts from inter-governmental transfers to reduce the unevenly distributed impacts caused by dam construction. However, overall the inter-governmental fiscal transfer efforts were not large enough to fully correct those uneven distributions, reflected from a 2% decrease of per capita GDP in upstream counties and increase of per capita GDP in local and downstream counties. This paper may shed some lights on the governmental considerations in the decision making process for large hydrological infrastructures.

  7. Technology transfer 1995

    Energy Technology Data Exchange (ETDEWEB)

    1995-01-01

    Technology Transfer 1995 is intended to inform the US industrial and academic sectors about the many opportunities they have to form partnerships with the US Department of Energy (DOE) for the mutual advantage of the individual institutions, DOE, and the nation as a whole. It also describes some of the growing number of remarkable achievements resulting from such partnerships. These partnership success stories offer ample evidence that Americans are learning how to work together to secure major benefits for the nation--by combining the technological, scientific, and human resources resident in national laboratories with those in industry and academia. The benefits include more and better jobs for Americans, improved productivity and global competitiveness for technology-based industries, and a more efficient government laboratory system.

  8. Heat transfer physics

    CERN Document Server

    Kaviany, Massoud

    2014-01-01

    This graduate textbook describes atomic-level kinetics (mechanisms and rates) of thermal energy storage, transport (conduction, convection, and radiation), and transformation (various energy conversions) by principal energy carriers. The approach combines the fundamentals of molecular orbitals-potentials, statistical thermodynamics, computational molecular dynamics, quantum energy states, transport theories, solid-state and fluid-state physics, and quantum optics. The textbook presents a unified theory, over fine-structure/molecular-dynamics/Boltzmann/macroscopic length and time scales, of heat transfer kinetics in terms of transition rates and relaxation times, and its modern applications, including nano- and microscale size effects. Numerous examples, illustrations, and homework problems with answers that enhance learning are included. This new edition includes applications in energy conversion (including chemical bond, nuclear, and solar), expanded examples of size effects, inclusion of junction quantum tr...

  9. Transfer Pricing and FDI

    Directory of Open Access Journals (Sweden)

    Patricia-Sabina Macelaru

    2013-08-01

    Full Text Available FDI analysis is usually performed within the frame of the win-win hypothesis. However, we believe that certain circumstances (MNEs following their own business objectives, lack of appropriate regulations, non-observance of the arm’s length principle may generate disproportionate advantages at the level of FDI stakeholders. The disequilibrium between reinvested profits and repatriated profits may be viewed as a proof of such disproportionate advantages of stakeholders involved in FDI. In addition to figures showing the comparison between reinvested and repatriated profits, as well as the way in which such indicators vary e.g. in case of abnormal business conditions (global economy collapse, we try to show that lack/misuse of transfer pricing regulations may generate even more disequilibrium, the MNEs using intra-group transactions as an additional way of repatriating non-taxable/low tax profits.

  10. General Relativistic Radiative Transfer

    CERN Document Server

    Knop, S; Baron, E

    2006-01-01

    We present a general method to calculate radiative transfer including scattering in the continuum as well as in lines in spherically symmetric systems that are influenced by the effects of general relativity (GR). We utilize a comoving wavelength ansatz that allows to resolve spectral lines throughout the atmosphere. The used numerical solution is an operator splitting (OS) technique that uses a characteristic formal solution. The bending of photon paths and the wavelength shifts due to the effects of GR are fully taken into account, as is the treatment of image generation in a curved spacetime. We describe the algorithm we use and demonstrate the effects of GR on the radiative transport of a two level atom line in a neutron star like atmosphere for various combinations of continuous and line scattering coefficients. In addition, we present grey continuum models and discuss the effects of different scattering albedos on the emergent spectra and the determination of effective temperatures and radii of neutron ...

  11. Elements of heat transfer

    CERN Document Server

    Rathakrishnan, Ethirajan

    2012-01-01

    1 Basic Concepts and Definitions1.1 Introduction1.1.1 Driving Potential1.2 Dimensions and Units1.2.1 Dimensional Homogeneity1.3 Closed and Open Systems1.3.1 Closed System (ControlMass)1.3.2 Isolated System1.3.3 Open System (ControlVolume)1.4 Forms of Energy1.4.1 Internal Energy1.5 Properties of a System1.5.1 Intensive and Extensive Properties1.6 State and Equilibrium1.7 Thermal and Calorical Properties1.7.1 Specific Heat of an Incompressible Substance1.7.2 Thermally Perfect Gas 1.8 The Perfect Gas1.9 Summary1.10 Exercise ProblemsConduction Heat Transfer2.1 Introduction2.2 Conduction Heat Trans

  12. Managerial technology transfer

    CERN Document Server

    2012-01-01

    Organisations need to think globally, but act locally - with a full appreciation of the diversity of local cultures. Major global companies must recognise that policies need to be managed with the broad context of business strategy and integrated into the work culture with the support of all elements of human resources management. Most currently, companies are accommodating national cultural differences while preserving work culture principals that encourage people to effectively execute the company's strategic objectives. Even to the casual observer, it is apparent that culture- a society's programming of the mind- has both a pervasive and changing influence on each national business environment. Global managers must recognise the influence of culture and be prepared to either respond to it or change it. This book examines current research in the study of managerial technology transfer.

  13. Knowledge Transfer Services

    Directory of Open Access Journals (Sweden)

    Albert Simard

    2009-03-01

    Full Text Available Le présent article décrit un modèle visant à faciliter la compréhension du processus de transfert du contenu depuis sa source jusqu’à son utilisation. Un groupe de travail de Ressources naturelles Canada a étudié la nature du transfert des savoirs à l’aide d’un modèle de services, afin de découvrir et comprendre les modèles et processus sous-jacents. Les services de savoir sont des programmes qui créent et fournissent des produits organisationnels basés sur un contenu et ayant une valeur intégrée. Ces programmes sont destinés à être utilisés en interne ou transférés pour répondre aux souhaits et besoins d’un utilisateur externe. Les critères de conception du modèle sont les suivants : indépendance par rapport au contenu, concentration sur l’organisation, évolutivité, deux pilotes et deux niveaux de résolution. Le modèle est basé sur une chaîne de valeur dans laquelle la valeur est intégrée, déplacée ou extraite. Un système de services de savoir se divise en neuf étapes : générer, transformer, gérer, utiliser en interne, transférer, ajouter de la valeur, utiliser professionnellement, utiliser personnellement et évaluer. Les services de savoir sont fournis par l’intermédiaire d’un spectre de distribution allant de complexe à accessible. À chaque région du spectre de distribution correspond une série d’attributs qui influencent la manière dont les services sont fournis.This paper describes a model intended to increase understanding of how content is transferred from its source to its use. A Natural Resources Canada task group explored the nature of knowledge transfer with a services paradigm to discover and understand underlying patterns and processes. Knowledge Services are programs that produce and pro-vide content-based organizational outputs with embedded value that are intended to be used internally or transferred to meet external user wants or needs. Model design criteria

  14. Electron transfer in proteins.

    Science.gov (United States)

    Gray, H B; Winkler, J R

    1996-01-01

    Electron-transfer (ET) reactions are key steps in a diverse array of biological transformations ranging from photosynthesis to aerobic respiration. A powerful theoretical formalism has been developed that describes ET rates in terms of two parameters: the nuclear reorganization energy (lambda) and the electronic-coupling strength (HAB). Studies of ET reactions in ruthenium-modified proteins have probed lambda and HAB in several metalloproteins (cytochrome c, myoglobin, azurin). This work has shown that protein reorganization energies are sensitive to the medium surrounding the redox sites and that an aqueous environment, in particular, leads to large reorganization energies. Analyses of electronic-coupling strengths suggest that the efficiency of long-range ET depends on the protein secondary structure: beta sheets appear to mediate coupling more efficiently than alpha-helical structures, and hydrogen bonds play a critical role in both. PMID:8811189

  15. Transfer of fuel assemblies

    International Nuclear Information System (INIS)

    Fuel assemblies of a nuclear reactor are transferred during fueling or refueling or the like by a crane. The work-engaging fixture of the crane picks up an assembly, removes it from this slot, transfers it to the deposit site and deposits it in its slot at the deposit site. The control for the crane includes a strain gauge connected to the crane line which raises and lowers the load. The strain gauge senses the load on the crane. The signal from the strain gauge is compared with setpoints; a high-level setpoint, a low-level setpoint and a slack-line setpoint. If the strain gauge signal exceeds the high-level setpoint, the line drive is disabled. This event may occur during raising of a fuel assembly which encounters resistance. The high-level setpoint may be overridden under proper precautions. The line drive is also disabled if the strain gauge signal is less than the low-level setpoint. This event occurs when a fuel assembly being deposited contacts the bottom of its slot or an obstruction in, or at the entry to the slot. To preclude lateral movement and possible damage to a fuel assembly suspended from the crane line, the traverse drive of the crane is disabled once the strain-gauge exceets the lov-level setpoint. The traverse drive can only be enabled after the strain-gauge signal is less than the slack-line set-point. This occurs when the lines has been set in slack-line setting. When the line is tensioned after slack-li ne setting, the traverse drive remains enabled only if the line has been disconnected from the fuel assembly

  16. Dual Space Technology Transfer

    Science.gov (United States)

    Kowbel, W.; Loutfy, R.

    2009-03-01

    Over the past fifteen years, MER has had several NASA SBIR Phase II programs in the area of space technology, based upon carbon-carbon (C-C) composites. In addition, in November 2004, leading edges supplied by MER provided the enabling technology to reach a Mach 10 record for an air breathing engine on the X-43 A flight. The MER business model constitutes a spin-off of technologies initially by incubating in house, and ultimately creating spin-off stand alone companies. FMC was formed to provide for technology transfer in the area of fabrication of C-C composites. FMC has acquired ISO 9000 and AS9100 quality certifications. FMC is fabricating under AS9100 certification, flight parts for several flight programs. In addition, FMC is expanding the application of carbon-carbon composites to several critical military programs. In addition to space technology transfer to critical military programs, FMC is becoming the world leader in the commercial area of low-cost C-C composites for furnace fixtures. Market penetrations have been accomplished in North America, Europe and Asia. Low-cost, quick turn-around and excellent quality of FMC products paves the way to greatly increased sales. In addition, FMC is actively pursuing a joint venture with a new partner, near closure, to become the leading supplier of high temperature carbon based composites. In addition, several other spin-off companies such as TMC, FiC, Li-Tech and NMIC were formed by MER with a plethora of potential space applications.

  17. Technology transfer from nuclear research

    International Nuclear Information System (INIS)

    A number of processes, components and instruments developed at the Bhabha Atomic Research Centre, (BARC), Bombay, find application in industry and are available for transfer to private or public sector undertakings for commercial exploitation. The Technology Transfer Group (TTG) constituted in January 1980 identifies such processes and prototypes which can be made available for transfer. This catalogue contains brief descriptions of such technologies and they are arranged under three groups, namely, Group A containing descriptions of technologies already transferred, Group B containing descriptions of technologies ready for transfer and Group C containing descriptions of technology transfer proposals being processed. The position in the above-mentioned groups is as on 1 March 1989. The BARC has also set up a Technology Corner where laboratory models and prototypes of instruments, equipment and components are displayed. These are described in the second part of the catalogue. (M.G.B.)

  18. Prospects for Money Transfer Models

    CERN Document Server

    Wang, Y; Xi, N; Wang, Yougui; Ding, Ning; Xi, Ning

    2005-01-01

    Recently, in order to explore the mechanism behind wealth or income distribution, several models have been proposed by applying principles of statistical mechanics. These models share some characteristics, such as consisting of a group of individual agents, a pile of money and a specific trading rule. Whatever the trading rule is, the most noteworthy fact is that money is always transferred from one agent to another in the transferring process. So we call them money transfer models. Besides explaining income and wealth distributions, money transfer models can also be applied to other disciplines. In this paper we summarize these areas as statistical distribution, economic mobility, transfer rate and money creation. First, money distribution (or income distribution) can be exhibited by recording the money stock (flow). Second, the economic mobility can be shown by tracing the change in wealth or income over time for each agent. Third, the transfer rate of money and its determinants can be analyzed by tracing t...

  19. Nuclear transfer: Progress and quandaries

    OpenAIRE

    Zhou Qi; Jouneau Alice; Li Ziyi; Li Xuemei; Renard Jean-Paul

    2003-01-01

    Abstract Cloning mammals by nuclear transfer is a powerful technique that is quickly advancing the development of genetically defined animal models. However, the overall efficiency of nuclear transfer is still very low and several hurdles remain before the power of this technique will be fully harnessed. Among these hurdles include an incomplete understanding of biologic processes that control epigenetic reprogramming of the donor genome following nuclear transfer. Incomplete epigenetic repro...

  20. Fiscal Transfers and Fiscal Sustainability

    OpenAIRE

    Potrafke, Niklas; Reischmann, Markus

    2014-01-01

    We examine whether US and German state governments pursue sustainable fiscal policies taking into account fiscal transfers. Using panel data techniques we investigate whether the debt-to-GDP ratio had a positive influence on the primary surplus (Bohn-model). We show that including/excluding fiscal transfers changes the results. If fiscal transfers are not included in the primary surplus, the test results do not indicate that the US and German state governments pursued sustainable fiscal polic...

  1. The economics of international transfers

    OpenAIRE

    Brakman, Steven; Marrewijk, Charles van

    1998-01-01

    textabstractInternational transfers have attracted the attention of economists ever since the famous debate between Keynes and Ohlin on German reparation payments after World War I. Today the subject is of even greater importance with billions of dollars flowing between nations as unilateral transfers. However the emphasis has shifted from balance-of-payments issues to the welfare consequences following a transfer, and in particular the welfare issues arising from aid to developing countries....

  2. SEMANTIC TRANSFERS: CRITERIA FOR CLASSIFICATION

    Directory of Open Access Journals (Sweden)

    Moskvin, V.P.

    2016-03-01

    Full Text Available There is represented the general classification of semantic transfers. As the research has shown, transfers can be systematized based on four parameters: 1 the type of associations lying on their basis: similarity, contiguity and contrast, the associations by similarity and contrast being regarded as the basis for taxonomic transfers (from genus to species, from species to genus, from species to species, etc.; 2 the functional parameter: functionally relevant and irrelevant; 3 the sphere of action: transfer applies both to lexical and grammatical semantics; 4 the degree of ex-pressiveness: thus, the metonymic associations are more predictable than the metaphoric ones.

  3. Free Flap Functional Muscle Transfers.

    Science.gov (United States)

    Garcia, Ryan M; Ruch, David S

    2016-08-01

    Free functional muscle transfers remain a powerful reconstructive tool to restore upper extremity function when other options such as tendon or nerve transfers are not available. This reconstructive technique is commonly used for patients following trauma, ischemic contractures, and brachial plexopathies. Variable outcomes have been reported following free functional muscle transfers that are related to motor nerve availability and reinnervation. This article highlights considerations around donor motor nerve selection, dissection, and use of the gracilis muscle, and the surgical approach to performing a free functional muscle transfer to restore elbow flexion and/or digit flexion. PMID:27387083

  4. Oocyte transfer and gamete intrafallopian transfer in the mare.

    Science.gov (United States)

    Carnevale, E M

    2004-07-01

    Methods for the collection and transfer of equine oocytes have been developed, and uses of these techniques have resulted in new clinical and research possibilities. Because oocyte transfer avoids reproductive problems associated with the oviduct, uterus, and cervix, pregnancies can be produced from many mares that cannot carry a pregnancy or produce embryos. Oocytes for clinical transfers are usually collected from preovulatory follicles and cultured for a short interval or transferred directly into a recipient's oviduct. For oocyte transfer, the recipient is inseminated within the uterus. A large number (1 x 10(9) to 2 x 10(9)) of motile sperms are preferred for inseminations. In contrast, sperm and oocyte are transferred into the oviduct during gamete intrafallopian transfer (GIFT). Therefore, a lower number (1 x 10(5) to 2 x 10(5)) of sperm can be used. Potentially, GIFT could be used in situations where sperm numbers are limited. Use of oocyte transfer and GIFT in clinical and research settings will aid us in understanding the interactions between oocyte, sperm, and oviduct in the equine. PMID:15271484

  5. Transference, Counter-Transference, and Reflexivity in Intercultural Education

    Science.gov (United States)

    Shim, Jenna Min

    2015-01-01

    The article addresses the contributions psychoanalytic theory, particularly its concepts of "transference and counter-transference," can make to our understanding of reflexivity in intercultural education (IE). After the introduction, the article is organized into three parts. The first part is a psychoanalytic discussion that focuses on…

  6. Block Transfer Handbook: Constructing and Negotiating Block Transfer Agreements.

    Science.gov (United States)

    Finlay, Finola

    The purpose of this handbook is to provide resources for institutions or articulation committees who are engaged in the task of investigating the feasibility of block transfer agreements. Block transfer is the process whereby a block of credits is granted to students who have successfully completed a certificate, diploma, or cluster of courses…

  7. Thermodynamic Basis of Electron Transfer in Dihydroorotate Dehydrogenase B from Lactococcus lactis:  Analysis by Potentiometry, EPR Spectroscopy, and ENDOR Spectroscopy

    DEFF Research Database (Denmark)

    Mohnsen, Al-Walid A.; Rigby, Stephen E. J.; Jensen, Kaj Frank;

    2004-01-01

    Dihydroorotate dehydrogenase B (DHODB) is a complex iron-sulfur flavoprotein that catalyzes the conversion of dihydroorotate to orotate and the reduction of NAD+. The enzyme is a dimer of heterodimers containing an FMN, an FAD, and a 2Fe-2S center. UV-visible, EPR, and ENDOR spectroscopies have b...

  8. Gas turbine heat transfer and cooling technology

    CERN Document Server

    Han, Je-Chin; Ekkad, Srinath

    2012-01-01

    FundamentalsNeed for Turbine Blade CoolingTurbine-Cooling TechnologyTurbine Heat Transfer and Cooling IssuesStructure of the BookReview Articles and Book Chapters on Turbine Cooling and Heat TransferNew Information from 2000 to 2010ReferencesTurbine Heat TransferIntroductionTurbine-Stage Heat TransferCascade Vane Heat-Transfer ExperimentsCascade Blade Heat TransferAirfoil Endwall Heat TransferTurbine Rotor Blade Tip Heat TransferLeading-Edge Region Heat TransferFlat-Surface Heat TransferNew Information from 2000 to 20102.10 ClosureReferencesTurbine Film CoolingIntroductionFilm Cooling on Rotat

  9. Transfer to rice

    International Nuclear Information System (INIS)

    One of the critical foods for the intake of radionuclides by humans is rice (Oryza sativa L.), which is the dominant staple food crop in humid tropical and sub-tropical countries across the globe. Cultivation methods have important effects on plant uptake of radionuclides from soil. Most rice is produced under flooded conditions, i.e. in fields with a water layer of 5-15 cm deep on soil. This is unlike the situation in unsaturated fields where the soil conditions are significantly different, meaning that the soil-to-rice transfer factors (Fvs) need to be discussed separately from Fv values of other cereals grown under unsaturated field conditions. In this section, rice refers to the crop grown on wet paddy fields; since water management is the dominant method for rice cultivation this is the most common type. Rice Fv values were collected from papers in international journals, books and proceedings with peer reviewing processes and Fv values based on dry weight rice grain were summarized here. Fv data for fallout isotopes (e.g. 90Sr and 137Cs), neutron activation products (e.g. 54Mn, 60Co, etc.) or naturally existing radionluclides (e.g. 210Pb, 226Ra, 238U, etc.) and those for naturally existing stable elements under agricultural field conditions were listed. (author)

  10. Conduction heat transfer solutions

    International Nuclear Information System (INIS)

    This text is a collection of solutions to a variety of heat conduction problems found in numerous publications, such as textbooks, handbooks, journals, reports, etc. Its purpose is to assemble these solutions into one source that can facilitate the search for a particular problem solution. Generally, it is intended to be a handbook on the subject of heat conduction. There are twelve sections of solutions which correspond with the class of problems found in each. Geometry, state, boundary conditions, and other categories are used to classify the problems. Each problem is concisely described by geometry and condition statements, and many times a descriptive sketch is also included. The introduction presents a synopsis on the theory, differential equations, and boundary conditions for conduction heat transfer. Some discussion is given on the use and interpretation of solutions. Supplementary data such as mathematical functions, convection correlations, and thermal properties are included for aiding the user in computing numerical values from the solutions. 155 figs., 92 refs., 9 tabs

  11. Conduction heat transfer solutions

    International Nuclear Information System (INIS)

    This text is a collection of solutions to a variety of heat conduction problems found in numerous publications, such as textbooks, handbooks, journals, reports, etc. Its purpose is to assemble these solutions into one source that can facilitate the search for a particular problem solution. Generally, it is intended to be a handbook on the subject of heat conduction. This material is useful for engineers, scientists, technologists, and designers of all disciplines, particularly those who design thermal systems or estimate temperatures and heat transfer rates in structures. More than 500 problem solutions and relevant data are tabulated for easy retrieval. There are twelve sections of solutions which correspond with the class of problems found in each. Geometry, state, boundary conditions, and other categories are used to classify the problems. A case number is assigned to each problem for cross-referencing, and also for future reference. Each problem is concisely described by geometry and condition statements, and many times a descriptive sketch is also included. At least one source reference is given so that the user can review the methods used to derive the solutions. Problem solutions are given in the form of equations, graphs, and tables of data, all of which are also identified by problem case numbers and source references

  12. Transfers, Contracts and Strategic Games

    NARCIS (Netherlands)

    Kleppe, J.; Hendrickx, R.L.P.; Borm, P.E.M.; Garcia-Jurado, I.; Fiestras-Janeiro, G.

    2007-01-01

    This paper analyses the role of transfer payments and strategic con- tracting within two-person strategic form games with monetary pay- offs. First, it introduces the notion of transfer equilibrium as a strat- egy combination for which individual stability can be supported by allowing the possibilit

  13. Strammere retningslinjer om transfer pricing

    DEFF Research Database (Denmark)

    Rossing, Christian Plesner

    2015-01-01

    Transfer pricing vedrører prisfastsættelsen på transaktioner, der foregår mellem koncernforbundne selskaber og er fortsat et tema, der nyder stort fokus hos både multinationale koncerner og skattemyndigheder. For den multinationale koncern er transfer pricing i høj grad en aktivitet, der består i...

  14. HYDROGEN TRANSFER IN CATALYTIC CRACKING

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Hydrogen transfer is an important secondary reaction of catalytic cracking reactions, which affects product yield distribution and product quality. It is an exothermic reaction with low activation energy around 43.3 kJ/mol. Catalyst properties and operation parameters in catalytic cracking greatly influence the hydrogen transfer reaction. Satisfactory results are expected through careful selection of proper catalysts and operation conditions.

  15. Language Transfer and English Teaching

    Institute of Scientific and Technical Information of China (English)

    夏矫

    2008-01-01

    @@ 1.Introduction In English language teaching,language transfer has been a controversial topic and more linguistic researchers have a better and more comprehensive understanding of it.Transfer means the influence resulting from the similarities and differences between the English language and mother tongue which has been previously acquired.

  16. Honeywell technical order transfer tests

    Energy Technology Data Exchange (ETDEWEB)

    1988-02-01

    This report covers testing being conductd by the Air Force Logistics Command on the Military Standard for the Automated Interchange of Technical Information (AITI). The objective is to demonstrate the validity of the transfer protocol defined in the standard and the viability of standarized formats for the transfer of technical information defined in other specifications used by the standard. 1 fig., 3 tabs.

  17. Providing global WLCG transfer monitoring

    International Nuclear Information System (INIS)

    The WLCG[1] Transfers Dashboard is a monitoring system which aims to provide a global view of WLCG data transfers and to reduce redundancy in monitoring tasks performed by the LHC experiments. The system is designed to work transparently across LHC experiments and across the various technologies used for data transfer. Currently each LHC experiment monitors data transfers via experiment-specific systems but the overall cross-experiment picture is missing. Even for data transfers handled by FTS, which is used by 3 LHC experiments, monitoring tasks such as aggregation of FTS transfer statistics or estimation of transfer latencies are performed by every experiment separately. These tasks could be performed once, centrally, and then served to all experiments via a well-defined set of APIs. In the design and development of the new system, experience accumulated by the LHC experiments in the data management monitoring area is taken into account and a considerable part of the code of the ATLAS DDM Dashboard is being re-used. The paper describes the architecture of the Global Transfer monitoring system, the implementation of its components and the first prototype.

  18. Innovation through Knowledge Transfer 2012

    CERN Document Server

    Gabrys, Bogdan; Musial-Gabrys, Katarzyna; Roach, Jim; Innovation through Knowledge Transfer InnovationKT-2012

    2013-01-01

    Across the world there is growing awareness of the importance of innovation and knowledge transfer.  Innovation in the sense of generating new knowledge and making better use of existing knowledge, coupled with knowledge transfer and sharing paradigms, have never been more relevant to the universities, industry, commerce and the third sector.  This volume represents the proceedings of the Innovation through Knowledge Transfer 2012 Conference which formed an excellent opportunity to disseminate, share and discuss the impact of innovation, knowledge sharing, enterprise and entrepreneurship.  The volume contains papers presented at a Workshop on ‘The Meta Transfer of Knowledge: Challenges in the Transfer of Knowledge in Industry’, others from thematic sessions on ‘Next-Practice in University Based Open Innovation’,  ‘Social Innovation and Related Paradigms’, ‘Engagement with Industry and Commerce’ and ‘Knowledge Exchange’.  All papers were thoroughly reviewed by referees knowledgeable in...

  19. Involuntary transfer of Intellectual property

    Directory of Open Access Journals (Sweden)

    Saeed habiba

    2011-07-01

    Full Text Available IPR owners have a right about voluntary transfer but sometimes Intellectual property right transfer by force and thus, there are challenge that this article regard for its. IPR shall be devolved to their legitimate heirs after their death unless, owner indicate otherwise in their wills. The heirs have the exclusive right to exercise economic and moral rights, they decide upon publication of the work and in general do every exploitation. But, they shall exercise The decisive manner that IPR of holder intended before his death. On other hand, IPR may be liable to seizure or IPR have been used in mortgage loan. Thus they can be transfer to new person.Here, we regard to Involuntary transfer.This article highlight subject of involuntary transfer and analysis on aspects

  20. Mechanisms of Ligand Transfer by the Hepatic Tocopherol Transfer Protein*

    OpenAIRE

    Morley, Samantha; Cecchini, Matt; Zhang, Wendy; Virgulti, Alessandro; Noy, Noa; Atkinson, Jeffrey; Manor, Danny

    2008-01-01

    α-Tocopherol is a member of the vitamin E family that functions as the principal fat-soluble antioxidant in vertebrates. Body-wide distribution of tocopherol is regulated by the hepatic α-tocopherol transfer protein (αTTP), which stimulates secretion of the vitamin from hepatocytes to circulating lipoproteins. This biological activity of αTTP is thought to stem from its ability to facilitate the transfer of vitamin E between membranes, but the mechanism by which the pr...

  1. Optimum Inter terminal Transfer Trajectories

    Directory of Open Access Journals (Sweden)

    T. N. Srivastava

    1968-01-01

    Full Text Available Rocket trajectories in a gravitational field between two terminals with specified velocities at each terminal are investigated with a view to total velocity increment required in initiating the rocket along the transfer path at the first terminal and in the attainment of the given final velocity at the final terminal. The equations are transformed for transfer between circular orbits and numerical results for Earth-Mars transfer are calculated. Finally particular cases of the above problem are discussed and Stark's results is drived therefrom.

  2. Beam Transfer and Machine Protection

    CERN Document Server

    Kain, V

    2016-01-01

    Beam transfer, such as injection into or extraction from an accelerator, is one of the most critical moments in terms of machine protection in a high-intensity machine. Special equipment is used and machine protection aspects have to be taken into account in the design of the beam transfer concepts. A brief introduction of the principles of beam transfer and the equipment involved will be given in this lecture. The main concepts of machine protection for injection and extraction will be presented, with examples from the CERN SPS and LHC.

  3. Advances in industrial heat transfer

    CERN Document Server

    Minea, Alina Adriana

    2012-01-01

    Advances in Industrial Heat Transfer presents the basic principles of industrial heat transfer enhancement. Serving as a reference and guide for future research, this book presents a complete approach, from redesigning equipment to the use of nanofluids in industry. Based on the latest methods of the experiment and their interpretation, this book presents a unified conception of the industrial heat transfer process and procedures which will help decrease global energy consumption. Containing both theoretical and practical results, the book uses text, pictures, graphs, and definitions to illust

  4. Experimental Evidence on Transfer Pricing

    Directory of Open Access Journals (Sweden)

    Tran Quoc H.

    2016-06-01

    Full Text Available We use incentivized economics experiments to test both the point predictions and comparative static predictions of optimal transfer pricing models, comparing behavior under varying conditions, including wholly versus partially-owned subsidiaries and different tariff and tax rates. As predicted, we find that transfer prices are responsive to relative tax and tariff rates as well as ownership proportions. Additionally, we examine convergence and learning in this setting. While individuals do not choose optimal transfer prices, their choices converge to optimal levels with experience. This paper thus makes two important contributions. First, by comparing behavior with theoretical predictions it provides evidence of whether (and when individuals set transfer prices optimally. Second, by comparing behavior under conditions of full and partial ownership it provides evidence on the impact of policy interventions (like regulating ownership proportions by MNEs on tax revenues.

  5. Electronic fund transfer & the "unbanked"

    OpenAIRE

    Luxman Nathan

    1998-01-01

    As the Federal Government moves to switch most federal payments from paper check delivery to Direct Deposit by January 2, 1999, the Electronic Fund Transfer Initiative (EFT) attempts to educate consumers and serve the "unbanked."

  6. Transfer your ideas to society!

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Science and technology labs are the ideal places for developing innovative solutions. However, inventors sometimes don’t realize that their ideas can find an application in industry, which can in turn have a technical and economic impact on society. Some researchers may think that disclosing an invention is a time-consuming process which is worth doing only in very special cases. But one thing is certain: it is always worth informing the Knowledge and Technology Transfer group, as they will give you the correct advice and support. Don’t be afraid of the paperwork… it can be highly rewarding!   Why should researchers at CERN bother to disclose their inventions to the Knowledge and Technology Transfer Group first? “Because when inventors do so, a process to transfer the technology to industry is set in motion” explains Henning Huuse, Patent Portfolio Manager in the KTT Group. To facilitate this transfer, patent protection can be a useful tool. &...

  7. Information Transfer in Social Media

    OpenAIRE

    Steeg, Greg Ver; Galstyan, Aram

    2011-01-01

    Recent research has explored the increasingly important role of social media by examining the dynamics of individual and group behavior, characterizing patterns of information diffusion, and identifying influential individuals. In this paper we suggest a measure of causal relationships between nodes based on the information-theoretic notion of transfer entropy, or information transfer. This theoretically grounded measure is based on dynamic information, captures fine-grain notions of influenc...

  8. Involuntary transfer of Intellectual property

    OpenAIRE

    Saeed habiba; zahra shakeri

    2011-01-01

    IPR owners have a right about voluntary transfer but sometimes Intellectual property right transfer by force and thus, there are challenge that this article regard for its. IPR shall be devolved to their legitimate heirs after their death unless, owner indicate otherwise in their wills. The heirs have the exclusive right to exercise economic and moral rights, they decide upon publication of the work and in general do every exploitation. But, they shall exercise The decisive manner th...

  9. Knowledge Transfer in Space Science

    OpenAIRE

    Yuen, P. C.

    2010-01-01

    Knowledge Transfer (KT) is a major part of technical aspect in space science. By involving the research council funded Knowledge Transfer Account (KTA) programme and the university industrial and commercial partners, these strengthen the future research collaboration amongst the university, industrial, commercial, scientific and engineering communities. Since the space science research and development is a multi-billion pounds sterling industry, it is often referred as the most advanced resea...

  10. Why Have They Not Transferred?

    Science.gov (United States)

    Roberts, Hilda

    In 1986, a study was conducted at Rancho Santiago College (RSC) to determine the reasons that students whose educational goal was to transfer to a four-year college did not complete their objective. In fall 1983, 6,030 of the students enrolled at RSC indicated on their application for admission that they planned to transfer to a four-year college.…

  11. Knowledge transfer and expatriation in multinational corporations

    DEFF Research Database (Denmark)

    Minbaeva, Dana; Michailova, Snejina

    2004-01-01

    Research on multinational corporation (MNC) knowledge transfer has argued continuously for the behavior of knowledge senders to be a determinant of knowledge transfer. Although the importance of disseminative capacity regarding knowledge transfer has been illustrated in numerous conceptual studies...

  12. Sources and Information on Transfer Associate Degrees

    Science.gov (United States)

    Ayon, Carlos

    2012-01-01

    This chapter provides an annotated bibliography of articles about the effects of transfer associate degrees and related statewide transfer and articulation policies. It also provides links to transfer degree legislation in several states.

  13. Transfer of mother tongue in SLA

    Institute of Scientific and Technical Information of China (English)

    米海燕

    2012-01-01

    In SLA transfer of mother tongue can not be overlooked. And we group it into positive transfer and negative transfer, which are reflected on different levels including pronunciation, vocabulary, syntax and culture.

  14. Resource Transfers to the Elderly: Do Adult Children Substitute Financial Transfers for Time Transfers?

    OpenAIRE

    Julie Zissimopoulos

    2001-01-01

    Using the Health and Retirement Study, this research investigates whether an adult child substitutes financial transfers to an elderly parent for time transfers as the cost of his or her time increases. The author develops and estimates a model of the effect of a child's wage rate on time and money transferred to an elderly parent. She then calculates a wage elasticity and studies how this varies with the existence of substitutes such as siblings and a spouse, and how this varies by sex of th...

  15. Variation suggestive of horizontal gene transfer at a lipopolysaccharide (lps biosynthetic locus in Xanthomonas oryzae pv. oryzae, the bacterial leaf blight pathogen of rice

    Directory of Open Access Journals (Sweden)

    Sonti Ramesh V

    2004-10-01

    Full Text Available Abstract Background In animal pathogenic bacteria, horizontal gene transfer events (HGT have been frequently observed in genomic regions that encode functions involved in biosynthesis of the outer membrane located lipopolysaccharide (LPS. As a result, different strains of the same pathogen can have substantially different lps biosynthetic gene clusters. Since LPS is highly antigenic, the variation at lps loci is attributed to be of advantage in evading the host immune system. Although LPS has been suggested as a potentiator of plant defense responses, interstrain variation at lps biosynthetic gene clusters has not been reported for any plant pathogenic bacterium. Results We report here the complete sequence of a 12.2 kb virulence locus of Xanthomonas oryzae pv. oryzae (Xoo encoding six genes whose products are homologous to functions involved in LPS biosynthesis and transport. All six open reading frames (ORFs have atypical G+C content and altered codon usage, which are the hallmarks of genomic islands that are acquired by horizontal gene transfer. The lps locus is flanked by highly conserved genes, metB and etfA, respectively encoding cystathionine gamma lyase and electron transport flavoprotein. Interestingly, two different sets of lps genes are present at this locus in the plant pathogens, Xanthomonas campestris pv. campestris (Xcc and Xanthomonas axonopodis pv. citri (Xac. The genomic island is present in a number of Xoo strains from India and other Asian countries but is not present in two strains, one from India (BXO8 and another from Nepal (Nepal624 as well as the closely related rice pathogen, Xanthomonas oryzae pv. oryzicola (Xoor. TAIL-PCR analysis indicates that sequences related to Xac are present at the lps locus in both BXO8 and Nepal624. The Xoor strain has a hybrid lps gene cluster, with sequences at the metB and etfA ends, being most closely related to sequences from Xac and the tomato pathogen, Pseudomonas syringae pv. tomato

  16. Sphere Drag and Heat Transfer.

    Science.gov (United States)

    Duan, Zhipeng; He, Boshu; Duan, Yuanyuan

    2015-07-20

    Modelling fluid flows past a body is a general problem in science and engineering. Historical sphere drag and heat transfer data are critically examined. The appropriate drag coefficient is proposed to replace the inertia type definition proposed by Newton. It is found that the appropriate drag coefficient is a desirable dimensionless parameter to describe fluid flow physical behavior so that fluid flow problems can be solved in the simple and intuitive manner. The appropriate drag coefficient is presented graphically, and appears more general and reasonable to reflect the fluid flow physical behavior than the traditional century old drag coefficient diagram. Here we present drag and heat transfer experimental results which indicate that there exists a relationship in nature between the sphere drag and heat transfer. The role played by the heat flux has similar nature as the drag. The appropriate drag coefficient can be related to the Nusselt number. This finding opens new possibilities in predicting heat transfer characteristics by drag data. As heat transfer for flow over a body is inherently complex, the proposed simple means may provide an insight into the mechanism of heat transfer for flow past a body.

  17. The transfer of second language acquisition

    Institute of Scientific and Technical Information of China (English)

    Wang Yu Lu

    2016-01-01

    Language transfer is a very important phenomenon in second language acquisition(SLA), which many linguists and psychologists would like to research. People who learn second language must be familiar with the rules of their mother tongue, so they often transfer those rules into the second language unconsciously, and then transfers appear. Language transfer divided into positive and negative transfer. The article use Odlin' s definition of language transfer in SLA.

  18. Cryogenic Propellant Storage and Transfer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Cryogenic Propellant Storage and Transfer project will demonstrate the capability to safely and efficiently store, transfer and measure cryogenic propellants,...

  19. 7 CFR 987.151 - Interhandler transfers.

    Science.gov (United States)

    2010-01-01

    ... IN RIVERSIDE COUNTY, CALIFORNIA Administrative Rules Qualification to Regulation § 987.151 Interhandler transfers. When any handler transfers dates, other than product dates, to another handler,...

  20. Status report on radionuclide transfer

    International Nuclear Information System (INIS)

    At the suggestion of the Federal Minstry of the Interior, in June 1978, a group of scientists from several institutions who are active in the field of radionuclide transfer or are interested in these problems got together. During the discussions of the work team, especially the transfer soil/plants was emphasized. Then the work team set up a status report on the transfer of the radionuclides relevant in the sense of the radiation protection act. The nuclides H3 and C14, the isotopes of the Sr, J, and Cs, Tc99, the so-called corrosion nuclides Mn54, Fe59, co-isotopes and Zn65, and isotopes of Pu, Am, and Cm were regarded as important for a possible radiation exposition. Recent investigations revealed that also the natural radionuclides Ra226, Po210, and Pb210 should be covered by the investigations. The goal of this status report is to present the level of knowledge on the transfer of these radionuclides to man in a brief form, giving hints at the most important literature. It was requested by the Federal Ministry of the Interior, as fas as possible, to indicate transfer factors which are necessary for the radio-occology act to be decreed according to Para. 45 of the radiation protection act. Another goal of the report was to show the gap in the knowledge on the radio nuclide transfer. This was thought to help to create a basis for the decisions of the Federal Ministry concerning the support of other investigation projects in the field of transfer of radionuclides. (orig./MG)

  1. Dry spent nuclear fuel transfer

    International Nuclear Information System (INIS)

    Newport News Shipbuilding, (NNS), has been transferring spent nuclear fuel in a dry condition for over 25 years. It is because of this successful experience that NNS decided to venture into the design, construction and operation of a commercial dry fuel transfer project. NNS is developing a remote handling system for the dry transfer of spent nuclear fuel. The dry fuel transfer system is applicable to spent fuel pool-to-cask or cask-to-cask or both operations. It is designed to be compatible with existing storage cask technology as well as the developing multi-purpose canister design. The basis of NNS' design is simple. It must be capable of transferring all fuel designs, it must be capable of servicing 100 percent of the commercial nuclear plants, it must protect the public and nuclear operators, it must be operated cost efficiently and it must be transportable. Considering the basic design parameters, the following are more specific requirements included in the design: (a) Total weight of transfer cask less than 24 tons; (b) no requirement for permanent site modifications to support system utilization; (c) minimal radiation dose to operating personnel; (d) minimal generation of radioactive waste; (e) adaptability to any size and length fuel or cask; (f) portability of system allowing its efficient movement from site to site; (g) safe system; all possible ''off normal'' situations are being considered, and resultant safety systems are being engineered into NNS' design to mitigate problems. The primary focus of this presentation is to provide an overview of NNS' Dry Spent Nuclear Fuel Transfer System. (author). 5 refs

  2. Polarisation Transfer in Proton Compton Scattering at High Momentum Transfer

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, David

    2004-12-31

    The Jefferson Lab Hall A experiment E99-114 comprised a series of measurements to explore proton Compton scattering at high momentum transfer. For the first time, the polarisation transfer observables in the p (~ 0 ~ p) reaction were measured in the GeV energy range, where it is believed that quark-gluon degrees of freedom begin to dominate. The experiment utilised a circularly polarised photon beam incident on a liquid hydrogen target, with the scattered photon and recoil proton detected in a lead-glass calorimeter and a magnetic spectrometer, respectively.

  3. CANISTER TRANSFER SYSTEM DESCRIPTION DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    B. Gorpani

    2000-06-23

    The Canister Transfer System receives transportation casks containing large and small disposable canisters, unloads the canisters from the casks, stores the canisters as required, loads them into disposal containers (DCs), and prepares the empty casks for re-shipment. Cask unloading begins with cask inspection, sampling, and lid bolt removal operations. The cask lids are removed and the canisters are unloaded. Small canisters are loaded directly into a DC, or are stored until enough canisters are available to fill a DC. Large canisters are loaded directly into a DC. Transportation casks and related components are decontaminated as required, and empty casks are prepared for re-shipment. One independent, remotely operated canister transfer line is provided in the Waste Handling Building System. The canister transfer line consists of a Cask Transport System, Cask Preparation System, Canister Handling System, Disposal Container Transport System, an off-normal canister handling cell with a transfer tunnel connecting the two cells, and Control and Tracking System. The Canister Transfer System operating sequence begins with moving transportation casks to the cask preparation area with the Cask Transport System. The Cask Preparation System prepares the cask for unloading and consists of cask preparation manipulator, cask inspection and sampling equipment, and decontamination equipment. The Canister Handling System unloads the canister(s) and places them into a DC. Handling equipment consists of a bridge crane hoist, DC loading manipulator, lifting fixtures, and small canister staging racks. Once the cask has been unloaded, the Cask Preparation System decontaminates the cask exterior and returns it to the Carrier/Cask Handling System via the Cask Transport System. After the DC is fully loaded, the Disposal Container Transport System moves the DC to the Disposal Container Handling System for welding. To handle off-normal canisters, a separate off-normal canister handling

  4. Radioactivity transfer to animal products

    International Nuclear Information System (INIS)

    Information on the behaviour of strontium, caesium, ruthenium, plutonium and americium in a range of domestic animals is reviewed to form a basis for the specification of time-dependent mathematical models describing uptake, distribution and retention in various domestic animals. Transfer factors relating concentration in animal product to daily radioactivity intake are derived after 100 d continuous intake and at equilibrium. These transfer factors are compared with the available published literature and used as a basis for the derivation of feedingstuff conversion factors relating limiting concentrations in animal feedingstuffs to limiting concentrations in human foodstuffs for application to animals receiving commercial feedingstuffs after a nuclear accident. Recommended transfer factors for animal products in conditions of continuous discharge and models for application to field conditions after a nuclear accident are also presented. Transfer of caesium to animal products is more effective than that for the other elements considered here. Transfer to meat of lamb, fattening pig, and chickens is generally more effective than that for other animals and other products

  5. Nanofluid impingement jet heat transfer.

    Science.gov (United States)

    Zeitoun, Obida; Ali, Mohamed

    2012-02-17

    Experimental investigation to study the heat transfer between a vertical round alumina-water nanofluid jet and a horizontal circular round surface is carried out. Different jet flow rates, jet nozzle diameters, various circular disk diameters and three nanoparticles concentrations (0, 6.6 and 10%, respectively) are used. The experimental results indicate that using nanofluid as a heat transfer carrier can enhance the heat transfer process. For the same Reynolds number, the experimental data show an increase in the Nusselt numbers as the nanoparticle concentration increases. Size of heating disk diameters shows reverse effect on heat transfer. It is also found that presenting the data in terms of Reynolds number at impingement jet diameter can take into account on both effects of jet heights and nozzle diameter. Presenting the data in terms of Peclet numbers, at fixed impingement nozzle diameter, makes the data less sensitive to the percentage change of the nanoparticle concentrations. Finally, general heat transfer correlation is obtained verses Peclet numbers using nanoparticle concentrations and the nozzle diameter ratio as parameters.

  6. Some Metapsychological Considerations about Transference

    Directory of Open Access Journals (Sweden)

    Sergio Guillermo Castellanos-Urrego**

    2009-12-01

    Full Text Available This paper shows a metapsychological re-creation of transference from a conceptualization of representations as the units of psychism. Transferences have their origins in the effort of an unsatisfied libidinal investiture that continues to be active in the Unconscious, and which allows the primary process to inadvertently filter into the secondary process through a “false link”. Therefore, a current perception becomes identified with the expectative representation, which makes the individual believe that this new person will satisfy the aforementioned investiture. Transference neurosis is a psychoanalytic pillar, since only through it may one consciously and currently have access the repressed unconscious drives, a feature of childhood sexuality, and restart the psychosexual development.

  7. Heat Transfer Basics and Practice

    CERN Document Server

    Böckh, Peter

    2012-01-01

    The book provides an easy way to understand the fundamentals of heat transfer. The reader will acquire the ability to design and analyze heat exchangers. Without extensive derivation of the fundamentals, the latest correlations for heat transfer coefficients and their application are discussed. The following topics are presented - Steady state and transient heat conduction - Free and forced convection - Finned surfaces - Condensation and boiling - Radiation - Heat exchanger design - Problem-solving After introducing the basic terminology, the reader is made familiar with the different mechanisms of heat transfer. Their practical application is demonstrated in examples, which are available in the Internet as MathCad files for further use. Tables of material properties and formulas for their use in programs are included in the appendix. This book will serve as a valuable resource for both students and engineers in the industry. The author’s experience indicates that students, after 40 lectures and exercises ...

  8. Mass Transfer by Stellar Wind

    CERN Document Server

    Boffin, Henri M J

    2014-01-01

    I review the process of mass transfer in a binary system through a stellar wind, with an emphasis on systems containing a red giant. I show how wind accretion in a binary system is different from the usually assumed Bondi-Hoyle approximation, first as far as the flow's structure is concerned, but most importantly, also for the mass accretion and specific angular momentum loss. This has important implications on the evolution of the orbital parameters. I also discuss the impact of wind accretion, on the chemical pollution and change in spin of the accreting star. The last section deals with observations and covers systems that most likely went through wind mass transfer: barium and related stars, symbiotic stars and central stars of planetary nebulae (CSPN). The most recent observations of cool CSPN progenitors of barium stars, as well as of carbon-rich post-common envelope systems, are providing unique constraints on the mass transfer processes.

  9. Energy Transfer in molecular devices

    CERN Document Server

    Caraglio, M

    2014-01-01

    Protein machines often exhibit long range interplay between different sites in order to achieve their biological tasks. We investigate and characterize the non--linear energy localization and the basic mechanisms of energy transfer in protein devices. By studying two different model protein machines, with different biological functions, we show that genuinely non--linear phenomena are responsible for energy transport between the different machine sites involved in the biological functions. The energy transfer turns out to be extremely efficient from an energetic point of view: by changing the energy initially provided to the model device, we identify a well defined range of energies where the time for the energy transport to occur is minimal and the amount of transferred energy is maximum. Furthermore, by introducing an implicit solvent, we show that the energy is localized on the internal residues of the protein structure, thus minimizing the dissipation.

  10. Essentials of radiation heat transfer

    CERN Document Server

    Balaji

    2014-01-01

    Essentials of Radiation Heat Transfer is a textbook presenting the essential, fundamental information required to gain an understanding of radiation heat transfer and equips the reader with enough knowledge to be able to tackle more challenging problems. All concepts are reinforced by carefully chosen and fully worked examples, and exercise problems are provided at the end of every chapter. In a significant departure from other books on this subject, this book completely dispenses with the network method to solve problems of radiation heat transfer in surfaces. It instead presents the powerful radiosity-irradiation method and shows how this technique can be used to solve problems of radiation in enclosures made of one to any number of surfaces. The network method is not easily scalable. Secondly, the book introduces atmospheric radiation, which is now being considered as a potentially important area, in which engineers can contribute to the technology of remote sensing and atmospheric sciences in general, b...

  11. Reverse Knowledge Transfer in MNEs

    DEFF Research Database (Denmark)

    Mudambi, Ram; Piscitello, Lucia; Rabbiosi, Larissa

    2014-01-01

    It is now well recognized that multinational enterprises (MNEs) are differentiated networks wherein subsidiaries vary in terms of their ability to create new knowledge and competencies for their parent groups. In much of this theory, it is taken for granted that subsidiary innovativeness has...... a positive correlation with the extent of reverse knowledge transfers to the parent MNE. Relying on the headquarters-subsidiary view of the MNE, we argue that, beyond a point, increasing subsidiary innovativeness will be associated with lower reverse knowledge transfers. Further, we argue...... that this relationship is sensitive to the subsidiary entry mode. Using data from a sample of 293 Italian subsidiaries, we find strong support for our hypotheses. In particular, our results confirm that the effect of subsidiary innovativeness on reverse knowledge transfers displays an inverted-U shape...

  12. Advances in heat transfer volume 21

    CERN Document Server

    Hartnett †, James P; Cho, Young I

    1991-01-01

    This volume in a series on heat transfer covers the modelling of the dynamics of turbulent transport processes, supercritical pressures, hydrodynamics, mass transfer near rotating surfaces, lost heat in entropy and the mechanics of heat transfer in a multifluid bubbling pool. Other related titles are "Advances in Heat Transfer", volumes 18, 19 and 20.

  13. Parental Motivation in Family Farm Intergenerational Transfers

    OpenAIRE

    Lange, Kelly Y.; Johnson, Jeffrey W.; Johnson, Phillip N.; Hudson, Darren; Belasco, Eric J

    2011-01-01

    An intergenerational transfer model incorporating both altruism and exchange is presented for family farm transfers. A simulation study is conducted to test parental motivation in intergenerational transfers of family farm businesses. Results indicated that family farm intergenerational transfers are altruistically motivated.

  14. Software engineering technology transfer: Understanding the process

    Science.gov (United States)

    Zelkowitz, Marvin V.

    1993-01-01

    Technology transfer is of crucial concern to both government and industry today. In this report, the mechanisms developed by NASA to transfer technology are explored and the actual mechanisms used to transfer software development technologies are investigated. Time, cost, and effectiveness of software engineering technology transfer is reported.

  15. Transfer in Second Language Learning Process

    Institute of Scientific and Technical Information of China (English)

    刘辉琳

    2008-01-01

    Transfer is the carryover of the previous linguistic knowledge to the subsequent target language learning. Positive transfer facilitates while negative one impedes the acquisition of a second language. Therefore teachers and learners can enhance their efficiency by taking advantage of positive transfer and minimizing negative transfer or interference of their native languages.

  16. 26 CFR 1.679-3 - Transfers.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Transfers. 1.679-3 Section 1.679-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME... recognition of gain on the transfer, see section 684. Example 3. Transfer not treated as transfer to trust....

  17. Transference and Counter-Transference in Treating Incarcerated Sex Offenders.

    Science.gov (United States)

    Allen, Brad; Brekke, Karl E.

    1996-01-01

    Explores the processes involved in treating sex offenders. Focuses on how therapists can feel traumatized by this patient population, the dynamism of transference, and tactics used by sex offender patients, such as seduction, imitation, intimidation, and invalidation. Describes ways for therapists to maintain objectivity and use transference…

  18. Single-embryo transfer versus multiple-embryo transfer.

    Science.gov (United States)

    Gerris, Jan

    2009-01-01

    Despite the progress made in assisted reproductive technology, live birth rates remain disappointingly low. Multiple-embryo transfer has been an accepted practice with which to increase the success rate. This has led to a higher incidence of multiple-order births compared with natural conception, which not only increase the risk of mortality and morbidity to both mother and children but are also associated with social and economic consequences. Elective single-embryo transfer (eSET) was developed in an effort to increase singleton pregnancies in assisted reproduction. Studies comparing eSET with multiple-embryo transfer highlight the benefit of this approach and suggest that, with careful patient selection and the transfer of good-quality embryos, the risk of a multiple-order pregnancy can be reduced without significantly decreasing live birth rates. Although the use of eSET has gradually increased in clinical practice, its acceptance has been limited by factors such as availability of funding and awareness of the procedure. An open discussion of eSET is warranted in an effort to enable a broader understanding by physicians and patients of the merits of this approach. Ultimately, eSET may provide a more cost-effective, potentially safer approach to patients undergoing assisted reproduction technology.

  19. Macroeconomic level of technology transfer

    Directory of Open Access Journals (Sweden)

    Smirnova Nadezhda

    2016-04-01

    Full Text Available World practice of economic management has proved that the best indicator of competitiveness is achieved by that economic system, the economic units of which timely and adequately update the resource and technical base, thus achieving higher financial and economic indicators. Ensuring that sustainable development becomes possible due to the transfer of technological innovations, namely the diffusion from the developer to the customer on both commercial and free of charge basis. The article focuses on functioning of technology transfer at the macro level, namely the creation of its domestic models.

  20. Radiative transfer on discrete spaces

    CERN Document Server

    Preisendorfer, Rudolph W; Stark, M; Ulam, S

    1965-01-01

    Pure and Applied Mathematics, Volume 74: Radiative Transfer on Discrete Spaces presents the geometrical structure of natural light fields. This book describes in detail with mathematical precision the radiometric interactions of light-scattering media in terms of a few well established principles.Organized into four parts encompassing 15 chapters, this volume begins with an overview of the derivations of the practical formulas and the arrangement of formulas leading to numerical solution procedures of radiative transfer problems in plane-parallel media. This text then constructs radiative tran

  1. Heat transfer enhancement with nanofluids

    CERN Document Server

    Bianco, Vincenzo; Nardini, Sergio; Vafai, Kambiz

    2015-01-01

    Properties of NanofluidSamuel Paolucci and Gianluca PolitiExact Solutions and Their Implications in Anomalous Heat TransferWenhao Li, Chen Yang and Akira NakayamaMechanisms and Models of Thermal Conductivity in NanofluidsSeung-Hyun Lee and Seok Pil JangExperimental Methods for the Characterization of Thermophysical Properties of NanofluidsSergio Bobbo and Laura FedeleNanofluid Forced ConvectionGilles RoyExperimental Study of Convective Heat Transfer in NanofluidsEhsan B. Haghighi, Adi T. Utomo, Andrzej W. Pacek and Björn E. PalmPerformance of Heat Exchangers Using NanofluidsBengt Sundén and Za

  2. Helium transfer line installation details.

    CERN Multimedia

    G. Perinic

    2007-01-01

    A particularity of the 32 m long four in one helium transfer line in between the cold box in USC55 and the cavern UX5 is the fact that the transfer line passes through a hole in the crane rail support beam. In order to ensure the alignment of the suspension rail in the interconnecting tunnel with the hole in the rail support as well as the connection points at both ends required precise measurements of the given geometries as well as the installation of a temporary target for the verification of the theoretical predictions.

  3. Fundamental principles of heat transfer

    CERN Document Server

    Whitaker, Stephen

    1977-01-01

    Fundamental Principles of Heat Transfer introduces the fundamental concepts of heat transfer: conduction, convection, and radiation. It presents theoretical developments and example and design problems and illustrates the practical applications of fundamental principles. The chapters in this book cover various topics such as one-dimensional and transient heat conduction, energy and turbulent transport, forced convection, thermal radiation, and radiant energy exchange. There are example problems and solutions at the end of every chapter dealing with design problems. This book is a valuable int

  4. Styring af international transfer pricing

    DEFF Research Database (Denmark)

    Reuther, Peter; Rossing, Christian Plesner

    2011-01-01

    Nærværende artikel introducerer international transfer pricing, dels som et skatteretligt fænomen og dels som et værktøj til planlægning og økonomisk styring af koncernforbundne selskaber i en multinational virksomhed (MNV). Med udgangspunkt i en case-analyse af MNV’en gives der et konkret eksempel...... international transfer pricing i betragtning, når økonomiske styringssystemer i en MNV skal anvendes til planlægning og opfølgning....

  5. Advances in electron transfer chemistry

    CERN Document Server

    Mariano, Patrick S

    1995-01-01

    Advances in Electron Transfer Chemistry, Volume 4 presents the reaction mechanisms involving the movement of single electrons. This book discusses the electron transfer reactions in organic, biochemical, organometallic, and excited state systems. Organized into four chapters, this volume begins with an overview of the photochemical behavior of two classes of sulfonium salt derivatives. This text then examines the parameters that control the efficiencies for radical ion pair formation. Other chapters consider the progress in the development of parameters that control the dynamics and reaction p

  6. Transfer pricing as a tax compliance risk

    OpenAIRE

    Jost, Sven P.; Pfaffermayr, Michael; Winner, Hannes

    2010-01-01

    This paper contributes to the empirical literature on the transfer pricing behavior of multinational firms. Previous research mainly focuses on transfer pricing as a means of tax optimization. Our approach concentrates on transfer pricing as a critical compliance issue. Specifically, we investigate whether and to what extent the awareness of transfer pricing as a tax compliance issue responds to country and industry characteristics as well as firm-specifics. Empirically, the transfer pricing ...

  7. A REVIEW OF TECHNOLOGY TRANSFER MECHANISMS

    OpenAIRE

    L.I. Le Grange; A.J. Buys

    2012-01-01

    ENGLISH ABSTRACT: This paper gives a review of the theory of technology transfer mechanisms. It is intended as an overview for practitioners. Technology transfer is defined and the technology transfer process discussed. Various technology transfer management tools are presented, such as technology reviews, technology space maps, and technology balance sheets. It concludes with the application of the theory in the form of a new proposed model for technology transfer. The aim of the mo...

  8. Efficient transfer of francium atoms

    Science.gov (United States)

    Aubin, Seth; Behr, John; Gorelov, Alexander; Pearson, Matt; Tandecki, Michael; Collister, Robert; Gwinner, Gerald; Shiells, Kyle; Gomez, Eduardo; Orozco, Luis; Zhang, Jiehang; Zhao, Yanting; FrPNC Collaboration

    2016-05-01

    We report on the progress of the FrPNC collaboration towards Parity Non Conservation Measurements (PNC) using francium atoms at the TRIUMF accelerator. We demonstrate efficient transfer (higher than 40%) to the science vacuum chamber where the PNC measurements will be performed. The transfer uses a downward resonant push beam from the high-efficiency capture magneto optical trap (MOT) towards the science chamber where the atoms are recaptured in a second MOT. The transfer is very robust with respect to variations in the parameters (laser power, detuning, alignment, etc.). We accumulate a growing number of atoms at each transfer pulse (limited by the lifetime of the MOT) since the push beam does not eliminate the atoms already trapped in the science MOT. The number of atoms in the science MOT is on track to meet the requirements for competitive PNC measurements when high francium rates (previously demonstrated) are delivered to our apparatus. The catcher/neutralizer for the ion beam has been tested reliably to 100,000 heating/motion cycles. We present initial tests on the direct microwave excitation of the ground hyperfine transition at 45 GHz. Support from NSERC and NRC from Canada, NSF and Fulbright from USA, and CONACYT from Mexico.

  9. Mass Transfer Method and Apparatus

    DEFF Research Database (Denmark)

    1995-01-01

    The invention relates to a method for transferring mass between a flow of a first fluid, preferably a gas phase such as a combustion flue gas, and a flow of a second fluid, preferably a liquid phase, where the first fluid is contacted with the outer surface of porous (semi-permeable) membranes, e...

  10. Proton transfer in organic scaffolds

    Science.gov (United States)

    Basak, Dipankar

    This dissertation focuses on the fundamental understanding of the proton transfer process and translating the knowledge into design/development of new organic materials for efficient non-aqueous proton transport. For example, what controls the shuttling of a proton between two basic sites? a) Distance between two groups? or b) the basicity? c) What is the impact of protonation on molecular conformation when the basic sites are attached to rigid scaffolds? For this purpose, we developed several tunable proton sponges and studied proton transfer in these scaffolds theoretically as well as experimentally. Next we moved our attention to understand long-range proton conduction or proton transport. We introduced liquid crystalline (LC) proton conductor based on triphenylene molecule and established that activation energy barrier for proton transport is lower in the LC phase compared to the crystalline phase. Furthermore, we investigated the impact of several critical factors: the choice of the proton transferring groups, mobility of the charge carriers, intrinsic vs. extrinsic charge carrier concentrations and the molecular architectures on long-range proton transport. The outcome of this research will lead to a deeper understanding of non-aqueous proton transfer process and aid the design of next generation proton exchange membrane (PEM) for fuel cell.

  11. Subsidiary Autonomy and Knowledge Transfer

    DEFF Research Database (Denmark)

    Søberg, Peder Veng; Wæhrens, Brian Vejrum

    2015-01-01

    Purpose: This paper explores the effect of subsidiary autonomy on knowledge transfers during captive R&D offshoring to emerging markets. Design/methodology/approach: A framework to this end is developed and illustrated in relation to four cases of captive R&D offshoring to emerging markets. Findi...

  12. Student Transfer Matrix, Fall 1992.

    Science.gov (United States)

    Oklahoma State Regents for Higher Education, Oklahoma City.

    Comprised primarily of data matrices, this report provides information on students transferring from Oklahoma public and private post-secondary institutions to other public and private post-secondary institutions in the state in fall 1992. The report consists of nine sections. Section I provides an aggregate flow of all students in the state,…

  13. Ethical Considerations in Technology Transfer.

    Science.gov (United States)

    Froehlich, Thomas J.

    1991-01-01

    Examines ethical considerations involved in the transfer of appropriate information technology to less developed countries. Approaches to technology are considered; two philosophical frameworks for studying ethical considerations are discussed, i.e., the Kantian approach and the utilitarian perspective by John Stuart Mill; and integration of the…

  14. Placental transfer of selected radiopharmaceuticals

    International Nuclear Information System (INIS)

    This paper reviews animal experiments carried out to determine the transfer of radiopharmaceuticals from mother to fetus. Animal data are compared to any human data available. The radiopharmaceuticals included in the discussion are Tc-99m pertechnetate, Tc-99m DTPA, Ga-67 citrate and Tl-201 chloride. (6 tab., 5 refs.)

  15. Advances in heat transfer enhancement

    CERN Document Server

    Saha, Sujoy Kumar; Sundén, Bengt; Wu, Zan

    2016-01-01

    This Brief addresses the phenomena of heat transfer enhancement. A companion edition in the SpringerBrief Subseries on Thermal Engineering and Applied Science to three other monographs including “Critical Heat Flux in Flow Boiling in Microchannels,” this volume is idea for professionals, researchers, and graduate students concerned with electronic cooling.

  16. Stochastic resin transfer molding process

    CERN Document Server

    Park, M

    2016-01-01

    We consider one-dimensional and two-dimensional models of stochastic resin transfer molding process, which are formulated as random moving boundary problems. We study their properties, analytically in the one-dimensional case and numerically in the two-dimensional case. We show how variability of time to fill depends on correlation lengths and smoothness of a random permeability field.

  17. Transfer of Rights and Obligations

    DEFF Research Database (Denmark)

    Beale, Hugh; Ringe, Wolf-Georg

    2013-01-01

    This chapter compares the law on transfer of rights (i.e., assignment) in the Draft Common Frame of Reference (DCFR), English law, and German law. It first considers cases in which the three systems produce similar results before concentrating on situations in which the results and the interactions...

  18. Mass Transfer from Giant Donors

    CERN Document Server

    Pavlovskii, K

    2014-01-01

    The stability of mass transfer in binaries with convective giant donors remains an open question in modern astrophysics. There is a significant discrepancy between what the existing methods predict for a response to mass loss of the giant itself, as well as for the mass transfer rate during the Roche lobe overflow. Here we show that the recombination energy in the superadiabatic layer plays an important and hitherto unaccounted-for role in he donor's response to mass loss, in particular on its luminosity and effective temperature. Our improved optically thick nozzle method to calculate the mass transfer rate via $L_1$ allows us to evolve binary systems for a substantial Roche lobe overflow. We propose a new, strengthened criterion for the mass transfer instability, basing it on whether the donor experiences overflow through its outer Lagrangian point. We find that with the new criterion, if the donor has a well-developed outer convective envelope, the critical initial mass ratio for which a binary would evolv...

  19. Building Fitnes for Transfer - Transfering Manufacturing Knowledge Across Borders

    DEFF Research Database (Denmark)

    Wæhrens, Brian Vejrum; Madsen, Erik Skov; Riis, Jens Ove;

    2009-01-01

    A key problem of manufacturing transfer remains that it is often difficult to explain what a company really knows, or why what it does really works. Still, practice indicates that attention is focused on planning the physical move and on the knowledge associated with normal operations. Introducti...... elements of dispatching capacity and places it in a model in a broader context.......A key problem of manufacturing transfer remains that it is often difficult to explain what a company really knows, or why what it does really works. Still, practice indicates that attention is focused on planning the physical move and on the knowledge associated with normal operations. Introduction...... of a sending and a receiving unit leads to identification of the notion of respectively a dispatching and an absorptive capacity. Whereas the latter has been treated in the literature, the former represents a neglected area. Based on two case studies of relocation processes the paper identifies and discusses...

  20. Heat transfer correlations in mantle tanks

    DEFF Research Database (Denmark)

    Furbo, Simon; Knudsen, Søren

    2005-01-01

    the inlet increases, natural convection starts to dominate. The heat transfer between the wall of the inner hot water tank and the domestic water is governed by natural convection. The results of the CFD-calculations are used to determine improved heat transfer correlations based on dimensionless analysis...... of the inner hot water tank and the domestic water in all levels of the tank. The heat transfer analysis showed that the heat transfer near the mantle inlet port between the solar collector fluid in the mantle and the walls surrounding the mantle is in the mixed convection regime, and as the distance from....... The heat transfer determined by these correlations is compared to the heat transfer determined by the CFD-calculations. The comparisons showed a good agreement between the heat transfer determined by the heat transfer correlations and the heat transfer determined by CFD-calculations. Consequently, the heat...

  1. Intra-firm Horizontal Knowledge Transfer Management

    Institute of Scientific and Technical Information of China (English)

    WANG Yaowu; WANG Yanhang

    2009-01-01

    Knowledge transfer is widely emphasized as a strategic issue for firm competition. A model for intra-firm horizontal knowledge transfer is proposed to model horizontal knowledge transfer to solve some demerits in current knowledge transfer researches. The concept model of intra-firm horizontal knowledge transfer was described and a framework was provided to define the main components of thetransfer process. Horizontal knowledge transfer is that knowledge is transferred from the source to the same hierarchical level recipients as the target. Horizontal knowledge transfer constitutes a strategic area of knowledge management research. However, little is known about the circumstances under which one particular mechanism is the most appropriate. To address these issues, some significant conclusions are drawn concerning knowledge transfer mechanisms in a real-world setting.

  2. ASSEMBLY TRANSFER SYSTEM DESCRIPTION DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    B. Gorpani

    2000-06-26

    The Assembly Transfer System (ATS) receives, cools, and opens rail and truck transportation casks from the Carrier/Cask Handling System (CCHS). The system unloads transportation casks consisting of bare Spent Nuclear Fuel (SNF) assemblies, single element canisters, and Dual Purpose Canisters (DPCs). For casks containing DPCs, the system opens the DPCs and unloads the SNF. The system stages the assemblies, transfer assemblies to and from fuel-blending inventory pools, loads them into Disposal Containers (DCs), temporarily seals and inerts the DC, decontaminates the DC and transfers it to the Disposal Container Handling System. The system also prepares empty casks and DPCs for off-site shipment. Two identical Assembly Transfer System lines are provided in the Waste Handling Building (WHB). Each line operates independently to handle the waste transfer throughput and to support maintenance operations. Each system line primarily consists of wet and dry handling areas. The wet handling area includes a cask transport system, cask and DPC preparation system, and a wet assembly handling system. The basket transport system forms the transition between the wet and dry handling areas. The dry handling area includes the dry assembly handling system, assembly drying system, DC preparation system, and DC transport system. Both the wet and dry handling areas are controlled by the control and tracking system. The system operating sequence begins with moving transportation casks to the cask preparation area. The cask preparation operations consist of cask cavity gas sampling, cask venting, cask cool-down, outer lid removal, and inner shield plug lifting fixture attachment. Casks containing bare SNF (no DPC) are filled with water and placed in the cask unloading pool. The inner shield plugs are removed underwater. For casks containing a DPC, the cask lid(s) is removed, and the DPC is penetrated, sampled, vented, and cooled. A DPC lifting fixture is attached and the cask is placed

  3. Radionuclide transfer to animal products: revised recommended transfer coefficient values

    Energy Technology Data Exchange (ETDEWEB)

    Howard, B.J. [Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LAI 4AP (United Kingdom)], E-mail: bjho@ceh.ac.uk; Beresford, N.A.; Barnett, C.L. [Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LAI 4AP (United Kingdom); Fesenko, S. [International Atomic Energy Agency, 1400 Vienna (Austria)

    2009-03-15

    A compilation has been undertaken of data which can be used to derive animal product transfer coefficients for radionuclides, including an extensive review of Russian language information. The resultant database has been used to provide recommended transfer coefficient values for a range of radionuclides to (i) cow, sheep and goat milk, (ii) meat (muscle) of cattle, sheep, goats, pigs and poultry and (iii) eggs. The values are used in a new IAEA handbook on transfer parameters which replaces that referred to as 'TRS 364'. The paper outlines the approaches and procedures used to identify and collate data, and assumptions used. There are notable differences between the TRS 364 'expected' values and the recommended values in the revised Handbook from the new database. Of the recommended values, three milk values are at least an order of magnitude higher than the TRS 364 values (Cr, Pu (cow) Pu (sheep)) and one milk value is lower (Ni (cow)). For meat, four values (Am, Cd, Sb (beef) I (pork)) are at least an order of magnitude higher than the TRS 364 values and eight values are at least an order of magnitude lower (Ru, Pu (beef), Ru, Sr, Zn (sheep), Ru, Sr (pork), Mn (poultry)). Many data gaps remain.

  4. Radionuclide transfer to animal products: revised recommended transfer coefficient values

    International Nuclear Information System (INIS)

    A compilation has been undertaken of data which can be used to derive animal product transfer coefficients for radionuclides, including an extensive review of Russian language information. The resultant database has been used to provide recommended transfer coefficient values for a range of radionuclides to (i) cow, sheep and goat milk, (ii) meat (muscle) of cattle, sheep, goats, pigs and poultry and (iii) eggs. The values are used in a new IAEA handbook on transfer parameters which replaces that referred to as 'TRS 364'. The paper outlines the approaches and procedures used to identify and collate data, and assumptions used. There are notable differences between the TRS 364 'expected' values and the recommended values in the revised Handbook from the new database. Of the recommended values, three milk values are at least an order of magnitude higher than the TRS 364 values (Cr, Pu (cow) Pu (sheep)) and one milk value is lower (Ni (cow)). For meat, four values (Am, Cd, Sb (beef) I (pork)) are at least an order of magnitude higher than the TRS 364 values and eight values are at least an order of magnitude lower (Ru, Pu (beef), Ru, Sr, Zn (sheep), Ru, Sr (pork), Mn (poultry)). Many data gaps remain

  5. Stabbing simulations and DNA transfer.

    Science.gov (United States)

    Samie, Lydie; Hicks, Tacha; Castella, Vincent; Taroni, Franco

    2016-05-01

    Technical developments have made it possible to analyze very low amounts of DNA. This has many advantages, but the drawback of this technological progress is that interpretation of the results becomes increasingly complex: the number of mixed DNA profiles increased relatively to single source DNA profiles and stochastic effects in the DNA profile, such as drop-in and drop-out, are more frequently observed. Moreover, the relevance of low template DNA material regarding the activities alleged is not as straightforward as it was a few years ago, when for example large quantities of blood were recovered. The possibility of secondary and tertiary transfer is now becoming an issue. The purpose of this research is twofold: first, to study the transfer of DNA from the handler and secondly, to observe if handlers would transfer DNA from persons closely connected to them. We chose to mimic cases where the offender would attack a person with a knife. As a first approach, we envisaged that the defense would not give an alternative explanation for the origin of the DNA. In our transfer experiments (4 donors, 16 experiments each, 64 traces), 3% of the traces were single DNA profiles. Most of the time, the DNA profile of the person handling the knife was present as the major profile: in 83% of the traces the major contributor profile corresponded to the stabber's DNA profile (in single stains and mixtures). Mixture with no clear major/minor fraction (12%) were observed. 5% of the traces were considered of insufficient quality (more than 3 contributors, presence of a few minor peaks). In that case, we considered that the stabber's DNA was absent. In our experiments, no traces allowed excluding the stabber, however it must be noted that precautions were taken to minimize background DNA as knives were cleaned before the experiments. DNA profiles of the stabber's colleagues were not observed. We hope that this study will allow for a better understanding of the transfer mechanism and

  6. TRANSFER PANAS LUBANG HITAM SCHWARZSCHILD

    Directory of Open Access Journals (Sweden)

    Y Tiandho

    2015-07-01

    Full Text Available Mekanika kuantum menunjukkan bahwa lubang hitam memiliki temperatur sebagai indikasi dapat mengemisikan partikel. Persamaan transfer panas secara general mengandung operator Laplacian yang sifatnya dipengaruhi oleh ruang. Kelengkungan ruang-waktu di daerah sekitar lubang hitam sangat besar sehingga operator Laplacian untuk menghitung distribusi temperaturnya merupakan Laplacian ruang lengkung. Persamaan Fourier untuk lubang hitam Schwarzschild bergantung pada jarak dan radius Schwarzschild. Pada keadaan tunak solusi dari komponen radius mengandung polinomial Legendre dan solusi dari komponen sudut ruang mengadung fungsi spherical harmonics. Untuk kasus dengan persamaan diferensial terhadap waktu bernilai konstan solusi menyimpulkan bahwa temperatur bertambah seiring waktu. Hasil yang telah didapatkan secara umum dapat digunakan untuk menentukan distribusi temperatur pada ruang lengkung akibat suatu objek bermassa M. Koreksi ini sekaligus menggambarkan peristiwa transfer panas dalam konteks relativitas umum.Quantum mechanics show that black hole has temperature that indicated that black hole can emit particles.<0} {0>Persamaan transfer panas secara general mengandung operator Laplacian yang sifatnya dipengaruhi oleh ruang.<}0{>Generally the heat transfer equation contains Laplacian operators that is influenced by space.<0} {0>Kelengkungan ruang-waktu di daerah sekitar lubang hitam sangat besar sehingga operator Laplacian untuk menghitung distribusi temperaturnya merupakan Laplacian ruang lengkung.<}0{>The space-time arch in the surrounding of black hole is very big so that Laplacian operators to calculate the temperature distribution is the arch space Laplacian.<0} {0>Persamaan Fourier untuk lubang hitam Schwarzschild bergantung pada jarak dan radius Schwarzschild.<}0{>Fourier equation for Schwarzschild black hole is depended on the distance and radius of Schwarzschild.<0} {0>Pada keadaan tunak solusi dari komponen radius mengandung polinomial

  7. The electronic couplings in electron transfer and excitation energy transfer.

    Science.gov (United States)

    Hsu, Chao-Ping

    2009-04-21

    The transport of charge via electrons and the transport of excitation energy via excitons are two processes of fundamental importance in diverse areas of research. Characterization of electron transfer (ET) and excitation energy transfer (EET) rates are essential for a full understanding of, for instance, biological systems (such as respiration and photosynthesis) and opto-electronic devices (which interconvert electric and light energy). In this Account, we examine one of the parameters, the electronic coupling factor, for which reliable values are critical in determining transfer rates. Although ET and EET are different processes, many strategies for calculating the couplings share common themes. We emphasize the similarities in basic assumptions between the computational methods for the ET and EET couplings, examine the differences, and summarize the properties, advantages, and limits of the different computational methods. The electronic coupling factor is an off-diagonal Hamiltonian matrix element between the initial and final diabatic states in the transport processes. ET coupling is essentially the interaction of the two molecular orbitals (MOs) where the electron occupancy is changed. Singlet excitation energy transfer (SEET), however, contains a Frster dipole-dipole coupling as its most important constituent. Triplet excitation energy transfer (TEET) involves an exchange of two electrons of different spin and energy; thus, it is like an overlap interaction of two pairs of MOs. Strategies for calculating ET and EET couplings can be classified as (1) energy-gap-based approaches, (2) direct calculation of the off-diagonal matrix elements, or (3) use of an additional operator to describe the extent of charge or excitation localization and to calculate the coupling value. Some of the difficulties in calculating the couplings were recently resolved. Methods were developed to remove the nondynamical correlation problem from the highly precise coupled cluster

  8. System for Multicast File Transfer

    Directory of Open Access Journals (Sweden)

    Dorin Custura

    2012-03-01

    Full Text Available The distribution of big files over the network from a single source to a large number of recipients is not efficient by using standard client-server or even peer-to peer file transfer protocols.  Thus, the transfer of a hierarchy of big files to multiple destinations can be optimized in terms of bandwidth usage and data storage reads by using multicast networking. In order to achieve that, a simple application layer protocol can be imagined. It uses multicast UDP as transport and it provides a mechanism for data ordering and retransmission. Some security problems are also considered in this protocol, because at this time the Internet standards supporting multicast security are still in the development stage.

  9. Heat Transfer in Steelmaking Ladle

    Institute of Scientific and Technical Information of China (English)

    André Zimmer; (A)lvaro Niedersberg Correia Lima; Rafael Mello Trommer; Saulo Roca Bragan(c)a; Carlos Pérez Bergmann

    2008-01-01

    The heat transfer in a steelmaking ladle was studied. The evaluation of heat transfer of the steel was performed by measuring steel temperature in points including all refining steel process. In the ladle, the temperatures in the refractories and the shell were also measured. To evaluate the thermal profile between the hot and cold faces of the ladle in the slag line position, an experiment which shows the importance of thermal contact resistance was car-ried out. Higher heat losses in the tapping and the vacuum were verified. The temperature measurements of the ladle indicate distinct thermal profiles in each stage of steel refining. Moreover, aseach stage of the process depends on the previous one, the complexity of the ladle thermal control is incremental. So a complete model of heat losses in the ladle is complex.

  10. Transient Heat Transfer in Cylinpers.

    Directory of Open Access Journals (Sweden)

    M.G. Chopra

    2000-07-01

    Full Text Available A numerical solution has been obtained for transient heat transfer in cylinders by appropriate choice of body ,conforming grid points. The physical domain is transformed to computational domain using elliptic partial differential equation technique, wherein the grid spacing becomes uniform. The advantage of this method is that the discretisation of transformed equations. and accompanying boundary conditipns becdme very simple. The applicability of this method is very broad, as it can beused for carryinI giout study of any comple'x domain in contrast to finite difference methods, which have limited applicability. Detailedcalculations have been carried out to trace the evolution of temperaturedistribution frpm the initiial stages to the steadystate for circular cylinder, elliptical cylinder and square block with circular hole. This paper is aimed for general-shaped bodies and it has been applied to studytransient heat transfer in combustion-driven shock tube.

  11. Transfer reactions in nuclear astrophysics

    Science.gov (United States)

    Bardayan, D. W.

    2016-08-01

    To a high degree many aspects of the large-scale behavior of objects in the Universe are governed by the underlying nuclear physics. In fact the shell structure of nuclear physics is directly imprinted into the chemical abundances of the elements. The tranquility of the night sky is a direct result of the relatively slow rate of nuclear reactions that control and determines a star’s fate. Understanding the nuclear structure and reaction rates between nuclei is vital to understanding our Universe. Nuclear-transfer reactions make accessible a wealth of knowledge from which we can extract much of the required nuclear physics information. A review of transfer reactions for nuclear astrophysics is presented with an emphasis on the experimental challenges and opportunities for future development.

  12. PRAGMATIC TRANSFER IN REQUEST REALIZATIONS

    Directory of Open Access Journals (Sweden)

    Indawan Syahri

    2007-01-01

    Full Text Available This study investigates the pragmatic transfer in English request realizations made by EFL learners, i.e. the proficient learners. The subjects were students of an English Study Program who obtained TOEFL-like scores of at least 450. The data were collected by means of DCT-questionnaires and Role-plays. The results show that the subjects realize requests in the form of external modifications more frequently. Most of them embed their requests with supportive moves dominantly. They enfold the acts with the moves before, after or in both positions. Of the three positions, they mostly insert the moves initial position, i.e., through inductive patterns. This is due to pragmatic transfer.

  13. Free radical transfer in polymers

    International Nuclear Information System (INIS)

    For the present study of free-radical transfer in polymers pulse radiolysis and product studies have been carried out in aqueous solutions using thus far only the water-soluble polymers polyacrylic acid, polymethacrylic acid and polyvinyl alcohol. When OH radicals, generated in the radiolysis of N2O-saturated aqueous solutions, react with polymers the lifetime of the polymer radical thus created very much depends on the number of radicals per polymer chain. When there are a large number of radicals per chain their bimolecular decay may be faster than the corresponding (diffusion controlled) decay of monomeric radicals, but when the macromolecule contains only few or even just one radical their lifetime is considerably prolonged. Highly charged polymers such as polyacrylic acid at high pH attain a rod-like conformation which again favors a long lifetime of the radicals. Under such conditions, radical transfer reactions can occur. For example, in polyacrylic acid OH radicals generate two kinds of radicals side by side. The radical in β-position to the carboxylate group converts into the thermodynamically more stable α-radicals by an H-transfer reaction as can be followed by spectrophotometry. Besides radical transfer reactions β-fragmentation reactions occur causing chain scission. Such reactions can be followed in a pulse radiolysis experiment by conductometry, because counter ions are released upon chain scission. Such a process is especially effective in the case of polymethacrylic acid, where it results in a chain depolymerization. An intramolecular H-abstraction is also observed in the γ-radiolysis of polyacrylic acid with the corresponding peroxyl radicals. This causes a chain reaction to occur. The resulting hydroperoxides are unstable and decarboxylate given rise to acetylacetone-like products. In polyvinyl alcohol the peroxyl radicals in α-position to the alcohol function undergo HO2-elimination. This prevents a scission of the polymer chain in the

  14. Optimal Control of charge transfer

    OpenAIRE

    Werschnik, J.; Gross, E.K.U.

    2007-01-01

    In this work, we investigate how and to which extent a quantum system can be driven along a prescribed path in space by a suitably tailored laser pulse. The laser field is calculated with the help of quantum optimal control theory employing a time-dependent formulation for the control target. Within a two-dimensional (2D) model system we have successfully optimized laser fields for two distinct charge transfer processes. The resulting laser fields can be understood as a complicated interplay ...

  15. Defining the TECHNOLOGY TRANSFER ALLIANCE

    OpenAIRE

    Ahlbom, Gabriella; Åman, Anna

    2011-01-01

    The aim of this project was to define the Technology Transfer Alliance (TTA), a nonprofit organization for Higher Education Institutions supporting capacity building in ICT and renewable energy through a project-driven learning. TTA is today still only an idea, waiting to be launched, which is why the goals for this bachelor thesis are to establish partnerships with institutions that will support the reaching of the goals of TTA, as well as providing a more solid definition of the functions o...

  16. Transplacental transfer of environmental genotoxins

    DEFF Research Database (Denmark)

    Autrup, Herman; Vestergaard, Astrid Beck; Okkels, Henrik

    1995-01-01

    Transplacental transfer of genotoxic material has been determined by measuring the polycyclic aromatic hydrocarbon-albumin adduct level in serum isolated from the mother and the umbilical cord using a competitive ELISA assay and the antibody (8E11) against benzo[a]pyrene (B[a]P) tetrols. Smoking ...... that local production of incomplete combustion products, like vehicle exhaust or heat generation, is the major contributing factor to genotoxic compounds in the general environment....

  17. ADVANCED TECHNOLOGY AND KNOWLEDGE TRANSFER

    OpenAIRE

    Tandon, Geetanjali; Sonka, Steven T.

    2002-01-01

    This paper reports on a specific project, employing new technological capabilities to better transfer expert knowledge. The specific project considered for the paper is the World Initiative for Soy in Human Health (WISHH), a Multi Organization Enterprise promoting the use of soy and soy products in humanitarian and development aid around the world. VisIT, which stands for Visualization of Information Technology, is a potentially powerful organizational tool. It is compared against the traditi...

  18. Maternal immune transfer in mollusc.

    Science.gov (United States)

    Wang, Lingling; Yue, Feng; Song, Xiaorui; Song, Linsheng

    2015-02-01

    Maternal immunity refers to the immunity transferred from mother to offspring via egg, playing an important role in protecting the offspring at early life stages and contributing a trans-generational effect on offspring's phenotype. Because fertilization is external in most of the molluscs, oocytes and early embryos are directly exposed to pathogens in the seawater, and thus maternal immunity could provide a better protection before full maturation of their immunological systems. Several innate immune factors including pattern recognition receptors (PRRs) like lectins, and immune effectors like lysozyme, lipopolysaccharide binding protein/bacterial permeability-increasing proteins (LBP/BPI) and antioxidant enzymes have been identified as maternally derived immune factors in mollusc eggs. Among these immune factors, some maternally derived lectins and antibacterial factors have been proved to endue mollusc eggs with effective defense ability against pathogen infection, while the roles of other factors still remain untested. The physiological condition of mollusc broodstock has a profound effect on their offspring fitness. Many other factors such as nutrients, pathogens, environment conditions and pollutants could exert considerable influence on the maternal transfer of immunity. The parent molluscs which have encountered an immune stimulation endow their offspring with a trans-generational immune capability to protect them against infections effectively. The knowledge on maternal transfer of immunity and the trans-generational immune effect could provide us with an ideal management strategy of mollusc broodstock to improve the immunity of offspring and to establish a disease-resistant family for a long-term improvement of cultured stocks.

  19. Controlling Sulfuryl-Transfer Biology.

    Science.gov (United States)

    Cook, Ian; Wang, Ting; Wang, Wei; Kopp, Felix; Wu, Peng; Leyh, Thomas S

    2016-05-19

    In humans, the cytosolic sulfotransferases (SULTs) catalyze regiospecific transfer of the sulfuryl moiety (-SO3) from 3'-phosphoadenosine 5'-phosphosulfate to thousands of metabolites, including numerous signaling small molecules, and thus regulates their activities and half-lives. Imbalances in the in vivo set points of these reactions leads to disease. Here, with the goal of controlling sulfonation in vivo, molecular ligand-recognition principles in the SULT and nuclear receptor families are integrated in creating a strategy that can prevent sulfonation of a compound without significantly altering its receptor affinity, or inhibiting SULTS. The strategy is validated by using it to control the sulfonation and estrogen receptor (ER) activating activity of raloxifene (a US Food and Drug Administration-approved selective estrogen receptor modulator) and its derivatives. Preventing sulfonation is shown to enhance ER-activation efficacy 10(4)-fold in studies using Ishikawa cells. The strategy offers the opportunity to control sulfuryl transfer on a compound-by-compound basis, to enhance the efficacy of sulfonated drugs, and to explore the biology of sulfuryl transfer with unprecedented precision. PMID:27203377

  20. Ion transfer in contact electrification

    Science.gov (United States)

    Diaz, Arthur F.; Fenzel-Alexander, Debra; Wollmann, Daphne; Eisenberg, A.

    1990-07-01

    The contact charge on polymers is influenced by added organic salts, and the charge is higher when the additive is polymer-bound rather than molecular.'7 In our studies, the presence of an ionomer consisting of a polystyrene random copolymer with pendent N-methylpyridinium toluenesulfonate groups in the host resin produces a positive charge, and the charge is higher than with the molecular analog, 4-ethyl-N-methylpyridinium toluenesulfonate.68 These studies were made with powders, and the charge was activated by rolling the powder with larger sized particles. The charging is attributed to ion transfer, where the toluenesulfonate anion (OTs) transfers from one particle surface to the other, and the proposal is supported by the observation of OTs on the second surface by XPS. l'he different charge levels were attributed to the relative mobilities of the cation and the anion, where in the ionomers, the cation is 'anchored' to the polymer and only OTs is mobile. With the molecular salt, both ions can transfer, although in unequal amounts, thus producing a smaller net charge. We now report our results from the analyses of the charged powders with a Simpson charge spectrometer, which allow us to relate the charge distributions with the charge levels in these materials.

  1. Horizontal gene transfer in chromalveolates

    Directory of Open Access Journals (Sweden)

    Bhattacharya Debashish

    2007-09-01

    Full Text Available Abstract Background Horizontal gene transfer (HGT, the non-genealogical transfer of genetic material between different organisms, is considered a potentially important mechanism of genome evolution in eukaryotes. Using phylogenomic analyses of expressed sequence tag (EST data generated from a clonal cell line of a free living dinoflagellate alga Karenia brevis, we investigated the impact of HGT on genome evolution in unicellular chromalveolate protists. Results We identified 16 proteins that have originated in chromalveolates through ancient HGTs before the divergence of the genera Karenia and Karlodinium and one protein that was derived through a more recent HGT. Detailed analysis of the phylogeny and distribution of identified proteins demonstrates that eight have resulted from independent HGTs in several eukaryotic lineages. Conclusion Recurring intra- and interdomain gene exchange provides an important source of genetic novelty not only in parasitic taxa as previously demonstrated but as we show here, also in free-living protists. Investigating the tempo and mode of evolution of horizontally transferred genes in protists will therefore advance our understanding of mechanisms of adaptation in eukaryotes.

  2. Intermodal transfer of spent fuel

    International Nuclear Information System (INIS)

    As a result of the international standardization of containerized cargo handling in ports around the world, maritime shipment handling is particularly uniform. Thus, handier exposure parameters will be relatively constant for ship-truck and ship-rail transfers at ports throughout the world. Inspectors' doses are expected to vary because of jurisdictional considerations. The results of this study should be applicable to truck-to-rail transfers. A study of the movement of spent fuel casks through ports, including the loading and unloading of containers from cargo vessels, afforded an opportunity to estimate the radiation doses to those individuals handling the spent fuels with doses to the public along subsequent transportation routes of the fuel. A number of states require redundant inspections and for escorts over long distances on highways; thus handlers, inspectors, escort personnel, and others who are not normally classified as radiation workers may sustain doses high enough to warrant concern about occupational safety. This paper addresses the question of radiation safety for these workers. Data were obtained during, observation of the offloading of reactor spent fuel (research reactor spent fuel, in this instance) which included estimates of exposure times and distances for handlers, inspectors and other workers during offloading and overnight storage. Exposure times and distance were also for other workers, including crane operators, scale operators, security personnel and truck drivers. RADTRAN calculational models and parameter values then facilitated estimation of the dose to workers during incident-free ship-to-truck transfer of spent fuel

  3. Transference of Skills between Sports and Business.

    Science.gov (United States)

    Liu, Jonathan; Srivastava, Ashok; Woo, Hong Seng

    1998-01-01

    A literature review and survey on transferability of skills from sports to business and evidence of mutually beneficial skills transfer. Organizations sponsoring sports offered more than monetary assistance, including managerial help, computer equipment, marketing, etc. (SK)

  4. Knowledge transfer from public research organisations

    NARCIS (Netherlands)

    Arnold, Erik; Knee, Paula; Brown, Neil; Javorka, Zsuzsa; Giarracca, Flora; Sidiqui, Sabeen

    2012-01-01

    This study describes knowledge transfer from European universities and institutes to industry, focusing on the role of the Industrial Liaison / Technology / Knowledge Transfer Office function. It explores practices in European institutions and compares these with international ones, especially from

  5. Exocellular electron transfer in anaerobic microbial communities

    NARCIS (Netherlands)

    Stams, A.J.M.; Bok, de F.A.M.; Plugge, C.M.; Eekert, van M.H.A.; Dolfing, J.; Schraa, G.

    2006-01-01

    Exocellular electron transfer plays an important role in anaerobic microbial communities that degrade organic matter. Interspecies hydrogen transfer between microorganisms is the driving force for complete biodegradation in methanogenic environments. Many organic compounds are degraded by obligatory

  6. Tendon transfers for the drop foot.

    Science.gov (United States)

    Schweitzer, Karl M; Jones, Carroll P

    2014-03-01

    The paralytic drop foot represents a challenging problem for even the most experienced orthopedic surgeon. Careful patient selection, thorough preoperative examination and planning, and application of tendon transfer biomechanical and physiologic principles outlined in this article can lead to successful results, either through a posterior tibialis tendon transfer, Bridle transfer, or variations on these procedures. Achilles lengthening or gastrocnemius recession may also be needed at the time of tendon transfer. PMID:24548510

  7. Waste Feed Delivery Transfer System Analysis

    Energy Technology Data Exchange (ETDEWEB)

    JULYK, L.J.

    2000-05-05

    This document provides a documented basis for the required design pressure rating and pump pressure capacity of the Hanford Site waste-transfer system in support of the waste feed delivery to the privatization contractor for vitrification. The scope of the analysis includes the 200 East Area double-shell tank waste transfer pipeline system and the associated transfer system pumps for a11 Phase 1B and Phase 2 waste transfers from AN, AP, AW, AY, and A2 Tank Farms.

  8. Transfer Potentials shape and equilibrate Monetary Systems

    OpenAIRE

    Dieter Braun; Robert Fischer

    2002-01-01

    We analyze a monetary system of random money transfer on the basis of double entry bookkeeping. Without boundary conditions, we do not reach a price equilibrium and violate text-book formulas of economists quantity theory (MV=PQ). To match the resulting quantity of money with the model assumption of a constant price, we have to impose boundary conditions. They either restrict specific transfers globally or impose transfers locally. Both connect through a general framework of transfer potentia...

  9. Technology and technology transfer: some basic issues

    OpenAIRE

    Shamsavari, Ali; Adikibi, Owen; Taha, Yasser

    2002-01-01

    This paper addresses various issues relating to technology and transfer of technology such as technology and society, technology and science, channels and models of technology transfer, the role of multinational companies in transfer of technology, etc. The ultimate objective is to pose the question of relevance of some existing models and ideas like technological independence in an increasingly globalised world economy.

  10. Transfer across Second Language Acquisition Theories

    Science.gov (United States)

    Daftarifard, Parisa; Shirkhani, Servat

    2011-01-01

    Transfer has been discussed from different points of view since the advent of Contrastive Analysis Hypothesis [13], [8]. Mishina-Mori [19] has defied transfer as merging grammatical properties from one language to another. The effect of transfer from a first language (L1) to a second language (L2) or a third language (L3) has been viewed…

  11. Training Transfer: An Integrative Literature Review

    Science.gov (United States)

    Burke, Lisa A.; Hutchins, Holly M.

    2007-01-01

    Given the proliferation of training transfer studies in various disciplines, we provide an integrative and analytical review of factors impacting transfer of training. Relevant empirical research for transfer across the management, human resource development (HRD), training, adult learning, performance improvement, and psychology literatures is…

  12. Engineering calculations in radiative heat transfer

    CERN Document Server

    Gray, W A; Hopkins, D W

    1974-01-01

    Engineering Calculations in Radiative Heat Transfer is a six-chapter book that first explains the basic principles of thermal radiation and direct radiative transfer. Total exchange of radiation within an enclosure containing an absorbing or non-absorbing medium is then described. Subsequent chapters detail the radiative heat transfer applications and measurement of radiation and temperature.

  13. Training Transfer: Not the 10% Solution

    Science.gov (United States)

    Farrington, Jeanne

    2011-01-01

    Training transfer is a key concern for organizational stakeholders, training professionals, and researchers. Since Georgenson's (1982) article on transfer, his conversational gambit that only 10% of training transfers to performance on the job has been quoted often. This estimate suggests a low level of success with training programs in general,…

  14. 21 CFR 864.9875 - Transfer set.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Transfer set. 864.9875 Section 864.9875 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... § 864.9875 Transfer set. (a) Identification. A transfer set is a device intended for medical...

  15. Heat transfer coefficient for boiling carbon dioxide

    DEFF Research Database (Denmark)

    Knudsen, Hans Jørgen Høgaard; Jensen, Per Henrik

    1998-01-01

    Heat transfer coefficient and pressure drop for boiling carbon dioxide (R744) flowing in a horizontal pipe has been measured. The calculated heat transfer coeeficient has been compared with the Chart correlation of Shah. The Chart Correlation predits too low heat transfer coefficient but the ratio...

  16. Measuring information-transfer delays.

    Directory of Open Access Journals (Sweden)

    Michael Wibral

    Full Text Available In complex networks such as gene networks, traffic systems or brain circuits it is important to understand how long it takes for the different parts of the network to effectively influence one another. In the brain, for example, axonal delays between brain areas can amount to several tens of milliseconds, adding an intrinsic component to any timing-based processing of information. Inferring neural interaction delays is thus needed to interpret the information transfer revealed by any analysis of directed interactions across brain structures. However, a robust estimation of interaction delays from neural activity faces several challenges if modeling assumptions on interaction mechanisms are wrong or cannot be made. Here, we propose a robust estimator for neuronal interaction delays rooted in an information-theoretic framework, which allows a model-free exploration of interactions. In particular, we extend transfer entropy to account for delayed source-target interactions, while crucially retaining the conditioning on the embedded target state at the immediately previous time step. We prove that this particular extension is indeed guaranteed to identify interaction delays between two coupled systems and is the only relevant option in keeping with Wiener's principle of causality. We demonstrate the performance of our approach in detecting interaction delays on finite data by numerical simulations of stochastic and deterministic processes, as well as on local field potential recordings. We also show the ability of the extended transfer entropy to detect the presence of multiple delays, as well as feedback loops. While evaluated on neuroscience data, we expect the estimator to be useful in other fields dealing with network dynamics.

  17. Exploring the Critical Role of Motivation to Transfer in the Training Transfer Process

    Science.gov (United States)

    Grohmann, Anna; Beller, Johannes; Kauffeld, Simone

    2014-01-01

    The present study aims at exploring the critical role of motivation to transfer within the training transfer process. In a sample of N?=?252 employees of one industrial company, one peer rating and several self-ratings of transfer were used to investigate the mediating role of motivation to transfer in the relationship between training…

  18. 78 FR 17066 - Indirect Stock Transfers and Coordination Rule Exceptions; Transfers of Stock or Securities in...

    Science.gov (United States)

    2013-03-19

    ... Revenue Service 26 CFR Part 1 RIN 1545-BJ74 Indirect Stock Transfers and Coordination Rule Exceptions; Transfers of Stock or Securities in Outbound Asset Reorganizations AGENCY: Internal Revenue Service (IRS... between asset transfers and indirect stock transfers for certain outbound asset reorganizations....

  19. Social Support at the Workplace, Motivation to Transfer and Training Transfer: A Multilevel Indirect Effects Model

    Science.gov (United States)

    Massenberg, Ann-Christine; Spurk, Daniel; Kauffeld, Simone

    2015-01-01

    Supervisor support, peer support and transfer motivation have been identified as important predictors of training transfer. Transfer motivation is thought to mediate the support-training transfer relationship. Especially after team training interventions that include all team members (i.e. whole-team training), individual perception of these…

  20. Detecting lateral genetic material transfer

    CERN Document Server

    Calderón, C; Mireles, V; Miramontes, P

    2012-01-01

    The bioinformatical methods to detect lateral gene transfer events are mainly based on functional coding DNA characteristics. In this paper, we propose the use of DNA traits not depending on protein coding requirements. We introduce several semilocal variables that depend on DNA primary sequence and that reflect thermodynamic as well as physico-chemical magnitudes that are able to tell apart the genome of different organisms. After combining these variables in a neural classificator, we obtain results whose power of resolution go as far as to detect the exchange of genomic material between bacteria that are phylogenetically close.

  1. Low Median Nerve Transfers (Opponensplasty).

    Science.gov (United States)

    Chadderdon, Robert Christopher; Gaston, R Glenn

    2016-08-01

    Opposition is the placement of the thumb opposite the fingers into a position from which it can work. This motion requires thumb palmar abduction, flexion, and pronation, which are provided by the abductor pollicis brevis, flexor pollicis brevis (FPB), and opponens pollicis. In the setting of a median nerve palsy, this function is typically lost, although anatomic variations and the dual innervation of the FPB may prevent complete loss at times. There are multiple well described and accepted tendon transfers to restore opposition, none of which have been proven to be superior to the others. PMID:27387078

  2. Panspermia and horizontal gene transfer

    Science.gov (United States)

    Klyce, Brig

    2009-08-01

    Evidence that extremophiles are hardy and ubiquitous is helping to make panspermia a respectable theory. But even if life on Earth originally came from space, biologists assume that the subsequent evolution of life is still governed by the darwinian paradigm. In this review we show how panspermia could amend darwinism and point to a cosmic source for, not only extremophiles but, all of life. This version of panspermia can be called "strong panspermia." To support this theory we will discuss recent evidence pertaining to horizontal gene transfer, viruses, genes apparently older than the Earthly evolution of the features they encode, and primate-specific genes without identifiable precursors.

  3. Blowdown heat transfer experiment, (1)

    International Nuclear Information System (INIS)

    Blowdown heat transfer experiment has been carried out with a transparent test section to observe phenomena in coolant behavior during blowdown process. Experimental parameters are discharge position, initial system pressure, initial coolant temperature, power supply to heater rods and number of heater rods. At initial pressure 7-12 ata and initial power 6-50 kw per one heater rod, the flow condition in the test section is a major factor in determining time of DNB occurrence and physical process to DNB during blowdown. (auth.)

  4. Psychotherapy patient transfer: secondhand rose.

    Science.gov (United States)

    Sederer, L

    1975-10-01

    The author uses the analogy of the marketplace to examine the dynamics of the transfer of psychotherapy patients in university clinic settings. The outgoing therapist is the seller, the prospective therapist the buyer, and the patient the commodity--the secondhand Rose. Marketing techniques that are used in this buyers' market allow no active patient participation and are therefore antithetical to the tenets of psychotherapy. The author suggests early clarification of therapeutic goals, assignment of therapists on the basis of patient choice, and explanation of time frames and limits as means for ameliorating the problems he describes.

  5. Boiling Heat Transfer to Halogenated Hydrocarbon Refrigerants

    Science.gov (United States)

    Yoshida, Suguru; Fujita, Yasunobu

    The current state of knowledge on heat transfer to boiling refrigerants (halogenated hydrocarbons) in a pool and flowing inside a horizontal tube is reviewed with an emphasis on information relevant to the design of refrigerant evaporators, and some recommendations are made for future research. The review covers two-phase flow pattern, heat transfer characteristics, correlation of heat transfer coefficient, influence of oil, heat transfer augmentation, boiling from tube-bundle, influence of return bend, burnout heat flux, film boiling, dryout and post-dryout heat transfer.

  6. Dry Transfer Systems for Used Nuclear Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Brett W. Carlsen; Michaele BradyRaap

    2012-05-01

    The potential need for a dry transfer system (DTS) to enable retrieval of used nuclear fuel (UNF) for inspection or repackaging will increase as the duration and quantity of fuel in dry storage increases. This report explores the uses for a DTS, identifies associated general functional requirements, and reviews existing and proposed systems that currently perform dry fuel transfers. The focus of this paper is on the need for a DTS to enable transfer of bare fuel assemblies. Dry transfer systems for UNF canisters are currently available and in use for transferring loaded canisters between the drying station and storage and transportation casks.

  7. Pragmatic Transfer in Second Language Acquisition

    Institute of Scientific and Technical Information of China (English)

    李婷

    2011-01-01

    Pragmatic.transfer is a common phenomenon that exists in Second Language Acquisition. It is an increasingly important .research of interlanguage pragmatics in the last two decades. Based on the characteristics , it plays an important role in the success of cultural communication and Second Language Acquisition. Based on presenting the concept of pragmatic transfer, this paper presents the concept of pragmatic transfer in second language acquisition and introduces the classification of pragmatic transfer. Then, this paper proposes some suggestions to avoid negative pragmatic transfer in second language acquisition. It is hoped that this paper can help second language learners to develop their communicative competence and avoid pragmatic failures in intercultural communication.

  8. Investigating Knowledge Transfer Mechanisms for Oil Rigs

    DEFF Research Database (Denmark)

    Vianello, Giovanna; Ahmed, Saeema

    2009-01-01

    It is widely recognized, both in industry and academia, that clear strategies in knowledge transfer positively influence the success of a firm. A firm should support the transfer of knowledge by standardizing communication channels within and across departments, based upon personalization...... whilst designing a knowledge management system to support the systematic reuse of service knowledge......., codification or a combination of these two strategies. The characteristics of the business influence the choice of communication channels used for knowledge transfer. This paper presents a case study exploring the transfer of knowledge within and across projects, specifically the transfer of service knowledge...

  9. Tendon Transfers for the Hypoplastic Thumb.

    Science.gov (United States)

    Wall, Lindley B; Goldfarb, Charles A

    2016-08-01

    Thumb hypoplasia is a component of radial longitudinal deficiency. The severity of hypoplasia can range from a slightly smaller thumb to a complete absence. Types II and IIIA hypoplastic thumbs are candidates for reconstruction to improve function, stability, and strength. There are 2 commonly used tendon transfers that can augment thumb opposition strength: the Huber abductor digiti minimi muscle transfer and the flexor digitorum superficialis opposition transfer. Both transfers use ulnar-sided structures to augment the thenar musculature. The Huber opposition transfer increases thenar bulk, but does not provide additional tissue for metacarpophalangeal stability. PMID:27387085

  10. Analysing CMS transfers using Machine Learning techniques

    CERN Document Server

    Diotalevi, Tommaso

    2016-01-01

    LHC experiments transfer more than 10 PB/week between all grid sites using the FTS transfer service. In particular, CMS manages almost 5 PB/week of FTS transfers with PhEDEx (Physics Experiment Data Export). FTS sends metrics about each transfer (e.g. transfer rate, duration, size) to a central HDFS storage at CERN. The work done during these three months, here as a Summer Student, involved the usage of ML techniques, using a CMS framework called DCAFPilot, to process this new data and generate predictions of transfer latencies on all links between Grid sites. This analysis will provide, as a future service, the necessary information in order to proactively identify and maybe fix latency issued transfer over the WLCG.

  11. Electromechanical capacitor for energy transfer

    International Nuclear Information System (INIS)

    Inductive energy transfer between two magnets can be achieved with almost 100% efficiency with a transfer capacitor. However, the bulk and cost will be high, and reliability low if conventional capacitors are used. A homopolar machine, used as a capacitor, will be compact and economical. A homopolar machine was designed with counter-rotating copper disks completely immersed in a liquid metal (NaK-78) to work as a pulse capacitor. Absence of solid-brush collectors minimized wear and frictional losses. Wetting of the copper disks throughout the periphery by the liquid metal minimized the resistive losses at the collector interface. A liquid-metal collector would, however, introduce hydrodynamic and magnetohydrodynamic losses. The selected liquid metal, e.g., NaK-78 will produce the lowest of such losses among the available liquid metals. An electromechanical capacitor of this design was tested at various dc magnetic fields. Its measured capacitance was about 100 farads at a dc magnetic field of 1.15 tesla

  12. Transferability of glass lens molding

    Science.gov (United States)

    Katsuki, Masahide

    2006-02-01

    Sphere lenses have been used for long time. But it is well known that sphere lenses theoretically have spherical aberration, coma and so on. And, aspheric lenses attract attention recently. Plastic lenses are molded easily with injection machines, and are relatively low cost. They are suitable for mass production. On the other hand, glass lenses have several excellent features such as high refractive index, heat resistance and so on. Many aspheric glass lenses came to be used for the latest digital camera and mobile phone camera module. It is very difficult to produce aspheric glass lenses by conventional process of curve generating and polishing. For the solution of this problem, Glass Molding Machine was developed and is spreading through the market. High precision mold is necessary to mold glass lenses with Glass Molding Machine. The mold core is ground or turned by high precision NC aspheric generator. To obtain higher transferability of the mold core, the function of the molding machine and the conditions of molding are very important. But because of high molding temperature, there are factors of thermal expansion and contraction of the mold and glass material. And it is hard to avoid the factors. In this session, I introduce following items. [1] Technology of glass molding and the machine is introduced. [2] The transferability of glass molding is analyzed with some data of glass lenses molded. [3] Compensation of molding shape error is discussed with examples.

  13. Optical fiber data transfer system

    Science.gov (United States)

    Mcmillan, S. H.

    1988-01-01

    This Phase 2 effort applies the results of Phase 1 to design and fabricate an optical slip ring system for a helicopter rotor blade/wind tunnel application. In this application, there are two assemblies: one on the rotating portion of the mechanical system, one on the stationary portion. The assembly on the rotating portion digitizes and encodes 128 transducer signals from various parts of the blade, and optically transfers data across the noncontacting coupling. Two complete identical independent channels are provided. On the stationary side, the signals are decoded and one channel is transmitted in digital form to a computer for recording and analysis. The second channel reconstructs the analog transducer signals for real time observation. In the opposite direction, eight signal channels enable control signals to be passed from the stationary to the rotating part of the system. Power to the rotor mounted electronics is supplied via power slip rings. The advantages of the optical over the traditional electro-mechanical slip ring method of data transfer across a rotating joint are long life, low-maintenance, immunity to crosstalk, and wider bandwidth. Successful completion of this effort demonstrated that this method is practical and reliable, and can be implemented under difficult conditions of available space, power, environment, and stringent performance and equipment life requirements.

  14. Hydrogen-Atom Transfer Reactions.

    Science.gov (United States)

    Wang, Liang; Xiao, Jian

    2016-04-01

    The cascade [1,n]-hydrogen transfer/cyclization, recognized as the tert-amino effect one century ago, has received considerable interest in recent decades, and great achievements have been made. With the aid of this strategy, the inert C(sp(3))-H bonds can be directly functionalized into C-C, C-N, C-O bonds under catalysis of Lewis acids, Brønsted acids, as well as organocatalysts, and even merely under thermal conditions. Hydrogen can be transferred intramolecularly from hydrogen donor to acceptor in the form of hydride, or proton, followed by cyclization to furnish the cyclic products in processes featuring high atom economy. Methylene/methine adjacent to heteroatoms, e.g., nitrogen, oxygen, sulfur, can be exploited as hydride donor as well as methylene/methine without heteroatom assistance. Miscellaneous electrophilic subunits or intermediates, e.g., alkylidene malonate, carbophilic metal activated alkyne or allene, α,β-unsaturated aldehydes/ketone, saturated aldehydes/iminium, ketenimine/carbodiimide, metal carbenoid, electron-withdrawing groups activated allene/alkyne, in situ generated carbocation, can serve as hydride acceptors. This methodology has shown preeminent power to construct 5-, 6-, or 7-membered heterocyclic as well as carbon rings. In this chapter, various hydrogen donors and acceptors are adequately discussed. PMID:27573142

  15. Skills Development and Transfer Strategy

    International Nuclear Information System (INIS)

    South Africa as a developing country is faced with numerous challenges amongst them is the shortage of skills in the working environment. Skills shortage has been aggravated by the retirement of the ageing skilled workforce and emigration of most experienced professionals to first world countries. Some professionals once they acquire the experience they opt out for a consultative business. This leaves a gap or void in the industries which can results into poor performance and quality, lessening of business standards and loosing competition. This challenge need to be attended to, because it will lead to hiring of consultants in most jobs or having many young and less experienced professionals and new graduates filling these gaps. The South African Young Nuclear Professionals Society (SAYNPS) has developed a strategic plan to serve as a guideline on how these challenges mentioned above can be addressed [1]. The proposed strategy will be aligned with skills development in the line of work and should get support from the nuclear Industry. Young professionals and recent graduates are the most affected people who lack skills and shall benefit from these programmes. In order for skill development and transfer to be accomplished there should be a Skill Development and Transfer Strategy and procedures to be followed. (authors)

  16. Energy transfer in macromolecular arrays

    Science.gov (United States)

    Andrews, David L.; Jenkins, Robert D.

    2003-11-01

    Macromolecular systems comprised of many light-sensitive centres (the photosynthetic unit, dendrimers, and other highly symmetric multichromophore arrays) are important structures offering challenges to theoreticians and synthetic chemists alike. Here we outline novel photophysical interactions predicted and observed in such arrays. Using the tools of molecular quantum electrodynamics (QED) we present quantum amplitudes for a variety of higher-order resonance energy transfer (RET) schemes associated with well-known nonlinear optical effects such as two- and three-photon absorption. The initial analysis is extended to account for situations where the participant donor species are identical and exist in a highly symmetric environment, leading to the possible formation of excitons. It emerges from the QED theory that such excitons are closely associated with the higher-order RET processes. General results are interpreted by analyzing particular molecular architectures which offer interesting features such as rate enhancement or limitation and exciton pathway quenching. Applications in the areas of photosynthesis, molecular logic gates and low-intensity fluorescence energy transfer are predicted.

  17. Widespread horizontal transfer of retrotransposons.

    Science.gov (United States)

    Walsh, Ali Morton; Kortschak, R Daniel; Gardner, Michael G; Bertozzi, Terry; Adelson, David L

    2013-01-15

    In higher organisms such as vertebrates, it is generally believed that lateral transfer of genetic information does not readily occur, with the exception of retroviral infection. However, horizontal transfer (HT) of protein coding repetitive elements is the simplest way to explain the patchy distribution of BovB, a long interspersed element (LINE) about 3.2 kb long, that has been found in ruminants, marsupials, squamates, monotremes, and African mammals. BovB sequences are a major component of some of these genomes. Here we show that HT of BovB is significantly more widespread than believed, and we demonstrate the existence of two plausible arthropod vectors, specifically reptile ticks. A phylogenetic tree built from BovB sequences from species in all of these groups does not conform to expected evolutionary relationships of the species, and our analysis indicates that at least nine HT events are required to explain the observed topology. Our results provide compelling evidence for HT of genetic material that has transformed vertebrate genomes.

  18. ASPEK PERPAJAKAN DALAM PRAKTEK TRANSFER PRICING

    Directory of Open Access Journals (Sweden)

    Yenni Mangoting

    2000-01-01

    Full Text Available Transfer pricing is defined as a special price for sale that is used in exchange of interdivisional to record the revenue of the selling division and expense of the buying division. The main goal of transfer pricing is to evaluate and measure the performance of a company. But transfer pricing is often used by multinational companies to minimize tax paid through the re-engineering of price transferred among divisions. The key to a successful practice of transfer pricing from tax standpoint is the existence of related parties transactions. Related parties is relationship between one company with other company and this relationship happens because of such relationship between each company does not exist naturally.To regulate the tranfer pricing practice, the regulations govern the authority to realocate transfer price among divisions that have related parties transactions. Abstract in Bahasa Indonesia : Transfer pricing didefenisikan sebagai suatu harga jual khusus yang dipakai dalam pertukaran antardivisional untuk mencatat pendapatan divisi penjual (selling division dan biaya divisi pembeli (buying division. Tujuan utama dari transfer pricing adalah mengevaluasi dan mengukur kinerja perusahaan. Tetapi sering juga transfer pricing digunakan oleh perusahaan-perusahaan multinasional untuk meminimalkan jumlah pajak yang dibayar melalui rekayasa harga yang ditransfer antardivisi. Kunci utama keberhasilan transfer pricing dari sisi pajak adalah adanya transaksi karena adanya hubungan istimewa. Hubungan istimewa merupakan hubungan kepemilikan antara satu perusahaan dengan perusahaan lain dan hubungan ini terjadi karena adanya keterkaitan satu pihak dengan pihak lain yang tidak terdapat pada hubungan biasa. Untuk mengatur transfer pricing ini, undang-undang memberikan kewenangan kepada pihak fiskus untuk menentukan kembali jumlah harga transfer antar pihak-pihak yang mempunyai hubungan istimewa. Kata kunci: transfer pricing, hubungan istimewa, perusahaan

  19. Heterostructure Intervalley Transferred Electron Effects

    Institute of Scientific and Technical Information of China (English)

    XUE Fang-Shi

    2001-01-01

    A Gunn active layer is used as an X electron probe to detect the X tunnelling current in the GaAs-AlAs heterostructure, from which a new heterostructure intervalley transferred electron (HITE) device is obtained. In the 8 mm band, the highest pulse output power of these diodes is 2.65 W and the highest conversion efficiency is 18%. The dc and rf performance of the HITE devices was simulated by the band mixing resonant tunnelling theory and Monte Carlo transport simulation. The HITE effect has transformed the transit-time dipole-layer mode in the Gunn diode into a relaxation oscillation mode in the HITE device. From the comparison of simulated results to the measured data, the HITE effect is demonstrated straightforwardly

  20. Knowledge Transfer in Virtual Communities

    Directory of Open Access Journals (Sweden)

    Chiva Marilena PAPUC

    2012-06-01

    Full Text Available Increasing development of information and communications technology, continuously transform how the world transmit, receive and manage information. Knowledge transfer switch from classic source - passive receiver to a more complex model, where each receiver can become a new source that regenerates and is thought to enhance the information received by adding its own added value and further resending it to an enhanced group of new receivers, often bigger than initial group. A current study performed jointly by State University of Milan and Facebook revealed that the degree of separation between any two people fell through six levels (as Stanley Milgram's theory, 1960 to less than four between Facebook users, shows that new patterns of social communication tend to transform humanity from a sum of individuals in a common consciousness, able to act in the common interest of humanity.

  1. Surface defects as transfer matrices

    CERN Document Server

    Maruyoshi, Kazunobu

    2016-01-01

    The supersymmetric index of the 4d $\\mathcal{N} = 1$ theory realized by a brane tiling coincides with the partition function of an integrable 2d lattice model. We propose that a class of half-BPS surface defects in brane tiling models are represented on the lattice model side by transfer matrices constructed from L-operators. For the simplest surface defect in theories with $\\mathrm{SU}(2)$ flavor groups, we identify the relevant L-operator as that discovered by Sklyanin in the context of the eight-vertex model. We verify our proposal by computing the indices of class-$\\mathcal{S}$ and -$\\mathcal{S}_k$ theories in the presence of the surface defect.

  2. Credit Risk Transfer and Crunches

    DEFF Research Database (Denmark)

    Wigan, Duncan

    2010-01-01

    Rather than in terms of the inevitable demise of a destabilising process of speculation, this article explores the ‘credit crunch’ as a window on the fabrication, and measure of the proportions of a political shift driven by market actors and financial innovation. The Basel process reconceptualised...... banks as risk navigators and generated a competitive hierarchy within the global banking industry determined on a gauge of this capacity. This private regulatory regime promoted market inflation and rendered institutional liquidity and risk transfer definitive of market power. In turn, a ballooning...... credit derivatives market broke the limits of financial production and defined state actions in the face of crisis. A shift from a central concern with solvency to that of liquidity thinly masks a profound redistribution of power from the public to the private. By swapping private assets of uncertain...

  3. Miniature mechanical transfer optical coupler

    Science.gov (United States)

    Abel, Philip; Watterson, Carl

    2011-02-15

    A miniature mechanical transfer (MT) optical coupler ("MMTOC") for optically connecting a first plurality of optical fibers with at least one other plurality of optical fibers. The MMTOC may comprise a beam splitting element, a plurality of collimating lenses, and a plurality of alignment elements. The MMTOC may optically couple a first plurality of fibers disposed in a plurality of ferrules of a first MT connector with a second plurality of fibers disposed in a plurality of ferrules of a second MT connector and a third plurality of fibers disposed in a plurality of ferrules of a third MT connector. The beam splitting element may allow a portion of each beam of light from the first plurality of fibers to pass through to the second plurality of fibers and simultaneously reflect another portion of each beam of light from the first plurality of fibers to the third plurality of fibers.

  4. Benefit Transfer Studies: Myths, Pragmatism, and Idealism

    Science.gov (United States)

    Boyle, Kevin J.; Bergstrom, John C.

    1992-03-01

    Benefit transfer has been an ongoing, practical analysis for years in legal proceedings and government policy analyses where timely benefit estimates are critically dependent on the use of existing data. Most benefit transfer studies to date have been conducted behind closed doors and have not been open to scholarly review, and no systematic research agenda has been established to determine whether benefit transfer estimates are valid for public policy analyses. In this paper we propose a systematic, conceptual foundation for conducting benefit transfer studies, and suggest a research agenda to identify conditions under which valid benefit transfer estimates can be derived. We conclude, however, that this research agenda must be accompanied by improved conduct and reporting of original valuation studies before benefit transfer can become a widely used tool in public policy analyses.

  5. Heat and mass transfer in particulate suspensions

    CERN Document Server

    Michaelides, Efstathios E (Stathis)

    2013-01-01

    Heat and Mass Transfer in Particulate Suspensions is a critical review of the subject of heat and mass transfer related to particulate Suspensions, which include both fluid-particles and fluid-droplet Suspensions. Fundamentals, recent advances and industrial applications are examined. The subject of particulate heat and mass transfer is currently driven by two significant applications: energy transformations –primarily combustion – and heat transfer equipment. The first includes particle and droplet combustion processes in engineering Suspensions as diverse as the Fluidized Bed Reactors (FBR’s) and Internal Combustion Engines (ICE’s). On the heat transfer side, cooling with nanofluids, which include nanoparticles, has attracted a great deal of attention in the last decade both from the fundamental and the applied side and has produced several scientific publications. A monograph that combines the fundamentals of heat transfer with particulates as well as the modern applications of the subject would be...

  6. A dynamic approach to technology transfer

    International Nuclear Information System (INIS)

    Stone and Webster Engineering Corporation has developed a systematic program for achieving efficient, effective technology transfer. This program is based on transferring both know-why and know-how. The transfer of know-why and know-how is achieved most effectively by working in partnership with the recipient of the technology; by employing five primary transfer mechanisms, according to the type of learning required; by treating the technology transfer as a designed process rather than an isolated event; and by using a project management approach to control and direct the process. This paper describes the philosophy, process, and training mechanisms that have worked for Stone and Webster, as well as the project management approach needed for the most effective transfer of technology. (author)

  7. Modeling ozone mass transfer in reclaimed wastewater.

    Science.gov (United States)

    Jiang, Pan; Chen, Hsiao-Ting; Babcock, Roger W; Stenstrom, Michael K

    2009-01-01

    Ozone mass transfer in reclaimed water was evaluated at pilot scale to determine mass-transfer characteristics and reaction kinetics and to assess the use of oxygen as a surrogate to measure this process. Tests were conducted in a 40-L/min pilot plant over a 3-year period. Nonsteady-state mass-transfer analyses for both oxygen and ozone were performed for superficial gas flow rates ranging from 0.13m/min to 0.40m/min. The psi factor, which is the ratio of volumetric mass-transfer coefficients of ozone to oxygen, was determined. The decrease in oxygen transfer rate caused by contaminants in reclaimed water was only 10 to 15% compared to tap water. A simple mathematical model was developed to describe transfer rate and steady state ozone concentration. Ozone decay was modeled accurately as a pseudo first-order reaction between ozone and ozone-demanding materials.

  8. Transfer of technology. Foreign contributions and systems

    International Nuclear Information System (INIS)

    The transfer of technology involved when exporting nuclear plants to countries with less-developed industry requires the provision of specific object-related processing methods, and the transfer of basic technical know-how. Such transfer should be organized so that it is both effective and economical. This paper discusses such transfer requirements in the light of the Federal Republic of Germany's agreement to supply nuclear plant to Brazil. The three main phases of such technology transfer comprise, first, a determination of the framework for joint scientific work between the two contracting countries; second, co-operation based on detailed agreements between universities, scientific institutes, licensing authorities etc., and, third, the transfer of know-how, chiefly characterized by high-level co-operation at the industrial level, as well as special training programmes for key personnel etc. At this stage special attention must be paid to the co-ordination of the different activities. (author)

  9. Boiling Heat Transfer in Circulating Fluidized Beds

    Institute of Scientific and Technical Information of China (English)

    张利斌; 李修伦

    2001-01-01

    A model is proposed to predict boiling heat transfer coefficient in a three-phase circulating fluidized bed (CFB), which is a new type of evaporation boiling means for enhancing heat transfer and preventing fouling. To verify the model, experiments are conducted in a stainless steel column with 39 mm ID and 2.0 m height, in which the heat transfer coefficient is measured for different superficial velocities, steam pressures, particle concentrations and materials of particle. As the steam pressure and particle concentrations increase, the heat transfer coefficient in the bed increases. The heat transfer coefficient increases with the liquid velocity but it exhibits a local minimum.The heat transfer coefficient is correlated with cluster renewed model and two-mechanism method. The prediction of the model is in good agreement with experimental data.

  10. Boiling Heat Transfer in Circulating Fluidized Beds

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A model is proposed to predict boiling heat transfer coefficient in a three-phase circulating fluidized bed (CFB), which is a new type of evaporation boiling means for enhancing heat transfer and preventing fouling. To verify the model, experiments are conducted in a stainless steel column with 39mm ID and 2.0m height, in which the heat transfer coefficient is measured for different superficial velocities, steam pressures, particle concentrations and materials of particle. As the steam pressure and particle concentrations increase, the heat transfer coefficient in the bed increases. The heat transfer coefficient increases with the liquid velocity but it exhibits a local minimum. The heat transfer coefficient is correlated with cluster renewed model and two-mechanism method. The prediction of the model is in good agreement with experimental data.

  11. Transferring lean management infrastructure for increasing productivity

    Directory of Open Access Journals (Sweden)

    Ph.D.Daniel Georgescu

    2010-12-01

    Full Text Available These years, manufacturing function have been transferred rapidly and globally from matured countries to emerging countries. In this paper is about the critical elements for successful transfer of lean management among sites and countries. Based on this general descriptive analysis, current global transfer activity of Lean as well as its future direction is also described. According to the gradual progress of lean management transfer, necessity of its refinement/reinforcement is recognized and some research subjects are proposed for contributing further encouragement of its global activities. In this paper, based on this understanding, requisites for transfer of lean management are discussed through investigating global activity of Lean and specification of infrastructure enabling its smooth transfer is examined

  12. Controlled quantum state transfer via parity measurement

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this work,a scheme for controlled quantum state transfer is proposed using parity measurement in a cavity-waveguide system.As two special cases,two schemes of controlled quantum state transfer for one qubit and two qubits are investigated in detail.An important advantage is that controlled quantum state transfer can be completed by single-qubit rotations and the measurement of parity.Therefore,the present scheme might be realized in the scope of current experimental technology.

  13. The transfer of accelerator technology to industry

    International Nuclear Information System (INIS)

    The national laboratories and universities are sources for innovative accelerator technology developments. With the growing application of accelerators in such fields as semiconductor manufacturing, medical therapy isotope production, nuclear waste transmutation, materials testing, bomb detection, pure science, etc., it is becoming more important to transfer these technologies and build an accelerator industrial base. In this talk the methods of technology transfer, the issues involved in working with the labs and examples of successful technology transfers are discussed. (Author)

  14. Transfer pricing and debt shifting in multinationals

    OpenAIRE

    Schindler, Dirk; Schjelderup, Guttorm

    2014-01-01

    There is a growing concern that governments lose substantial corporate tax revenue because of profit shifting through transfer-pricing and thin-capitalization strategies. Existing literature studies profit shifting and transfer pricing separately. In practice, the choice of debt-to-asset ratios in affiliates and the transfer price of debt are interrelated management decisions that are also mutually affected by government regulation. This paper models these strategies as intertwined. We find t...

  15. Phonon-induced dynamic resonance energy transfer

    OpenAIRE

    Lim, James; Tame, Mark; Yee, Ki Hyuk; Lee, Joong-Sung; Lee, Jinhyoung

    2013-01-01

    In a network of interacting quantum systems achieving fast coherent energy transfer is a challenging task. While quantum systems are susceptible to a wide range of environmental factors, in many physical settings their interactions with quantized vibrations, or phonons, of a supporting structure are the most prevalent. This leads to noise and decoherence in the network, ultimately impacting the energy-transfer process. In this work, we introduce a novel type of coherent energy-transfer mechan...

  16. Orbital Express fluid transfer demonstration system

    Science.gov (United States)

    Rotenberger, Scott; SooHoo, David; Abraham, Gabriel

    2008-04-01

    Propellant resupply of orbiting spacecraft is no longer in the realm of high risk development. The recently concluded Orbital Express (OE) mission included a fluid transfer demonstration that operated the hardware and control logic in space, bringing the Technology Readiness Level to a solid TRL 7 (demonstration of a system prototype in an operational environment). Orbital Express (funded by the Defense Advanced Research Projects Agency, DARPA) was launched aboard an Atlas-V rocket on March 9th, 2007. The mission had the objective of demonstrating technologies needed for routine servicing of spacecraft, namely autonomous rendezvous and docking, propellant resupply, and orbital replacement unit transfer. The demonstration system used two spacecraft. A servicing vehicle (ASTRO) performed multiple dockings with the client (NextSat) spacecraft, and performed a variety of propellant transfers in addition to exchanges of a battery and computer. The fluid transfer and propulsion system onboard ASTRO, in addition to providing the six degree-of-freedom (6 DOF) thruster system for rendezvous and docking, demonstrated autonomous transfer of monopropellant hydrazine to or from the NextSat spacecraft 15 times while on orbit. The fluid transfer system aboard the NextSat vehicle was designed to simulate a variety of client systems, including both blowdown pressurization and pressure regulated propulsion systems. The fluid transfer demonstrations started with a low level of autonomy, where ground controllers were allowed to review the status of the demonstration at numerous points before authorizing the next steps to be performed. The final transfers were performed at a full autonomy level where the ground authorized the start of a transfer sequence and then monitored data as the transfer proceeded. The major steps of a fluid transfer included the following: mate of the coupling, leak check of the coupling, venting of the coupling, priming of the coupling, fluid transfer, gauging

  17. Finite element simulation of heat transfer

    CERN Document Server

    Bergheau, Jean-Michel

    2010-01-01

    This book introduces the finite element method applied to the resolution of industrial heat transfer problems. Starting from steady conduction, the method is gradually extended to transient regimes, to traditional non-linearities, and to convective phenomena. Coupled problems involving heat transfer are then presented. Three types of couplings are discussed: coupling through boundary conditions (such as radiative heat transfer in cavities), addition of state variables (such as metallurgical phase change), and coupling through partial differential equations (such as electrical phenomena).? A re

  18. Transfer Entropy Analysis of the Stock Market

    CERN Document Server

    Baek, S K; Kwon, O; Moon, H T; Baek, Seung Ki; Jung, Woo-Sung; Kwon, Okyu; Moon, Hie-Tae

    2005-01-01

    In terms of transfer entropy, we investigated the strength and the direction of information transfer in the US stock market. Through the directionality of the information transfer, the more influential company between the correlated ones can be found and also the market leading companies are selected. Our entropy analysis shows that the companies related with energy industries such as oil, gas, and electricity influence the whole market.

  19. Transferring World Class Production to Developing Countries

    DEFF Research Database (Denmark)

    Bruun, Peter; Mefford, Robert Neil

    1998-01-01

    Strategic reasons for firms to transfer world-class production methods and technology to developing countries are discussed and the importance of the management aspects of technology transfer are emphasized. A five stage model of the technology transfer process which bases the choice....... The barriers and challenges of implementation are considered, and a socio-technical systems approach is proposed as a way to addapt to local conditions....

  20. Transfer Pricing Documentation - A Current Issue

    OpenAIRE

    Violeta Isai; Ramona Maxim

    2016-01-01

    Rather quick development of the business environment has led to the implementation of legislative measures to meet the requirements and amendments thereto. With the adoption of the Fiscal Procedure Code and Order no. 442/2016 were founded transfer pricing procedures, denoting a means of making taxable transfer of a high tax country to a low tax country. These laws have laid down conditions that must be met and materiality thresholds that must take into account the taxpayer to draft transfer p...

  1. Controlled quantum state transfer via parity measurement

    Institute of Scientific and Technical Information of China (English)

    YUAN Quan; LI JiuHui

    2009-01-01

    In this work, a scheme for controlled quantum state transfer is proposed using parity measurement in a cavity-waveguide system. As two special cases, two schemes of controlled quantum state transfer for one qubit and two qubits are investigated in detail. An important advantage is that controlled quantum state transfer can be completed by single-qubit rotations and the measurement of parity. Therefore, the present scheme might be realized in the scope of current experimental technology.

  2. An integrated approach towards technology transfer

    OpenAIRE

    Wal, L.F. van der; Eldering, C.J.J.; Putten, N.J. van

    2010-01-01

    In 2001 the European Space Agency (ESA), the Dutch Ministry of Economic Affairs and the Netherlands Organisation of applied scientific research TNO initiated the Dutch Technology Transfer Programme (DTTP). Since then, 'technology transfer' has been a relevant part of Dutch space policy. The DTTP aimed to promote the transfer of knowledge and technology from the European space industry to Dutch companies outside the space sector. Full and easy access to this knowledge and technology may allow ...

  3. Earth--Mars Transfers with Ballistic Capture

    OpenAIRE

    Topputo, Francesco; Belbruno, Edward

    2014-01-01

    We construct a new type of transfer from the Earth to Mars, which ends in ballistic capture. This results in a substantial savings in capture $\\Delta v$ from that of a classical Hohmann transfer under certain conditions. This is accomplished by first becoming captured at Mars, very distant from the planet, and then from there, following a ballistic capture transfer to a desired altitude within a ballistic capture set. This is achieved by manipulating the stable sets, or sets of initial condit...

  4. Nerve transfer in brachial plexus traction injuries

    Directory of Open Access Journals (Sweden)

    Samardžić Miroslav M.

    2003-01-01

    Full Text Available Background. The aim of this study was to analyze the results of nerve transfer to the musculocutaneous and axillary nerves, using some technical modalities such as intercostal, spinal accessory or intraplexal transfer, and on the basis of the results to try to clarify the most common controversies concerning these operations. Methods. The study included 82 patients with brachial plexus traction injuries, who were operated on using various techniques of nerve transfer. The follow-up period was at least two years. The analysis of biceps and deltoid muscles recovery was performed according to the type of the donor nerve. Results. The corresponding rates of recovery for the musculocutaneous and axillary nerves were 46.7% and 68.1% in intercostal nerve transfer, 71.4% and 75% in accessory nerve transfer, 93.1% and 88.8% in nerve transfer of the brachial plexus collateral branches, and 55.5% and 60% in classical intraplexal nerve transfer, respectively. Comparative statistical analysis demonstrated significantly better final outcome and quality of recovery in regional nerve transfers in comparison to the other methods. Conclusion. Our findings suggest that nerve transfer of collateral branches, where possible, (such as in cases with upper or extended upper brachial plexus palsy might be a method of choice, offering better results and quality of recovery.

  5. Stability of the LHC transfer lines

    CERN Document Server

    Kain, V; Bartmann, W; Bracco, C; Goddard, B; Meddahi, M; Uythoven, J; Wenninger, J

    2011-01-01

    The LHC is filled from the SPS through two 3 km transfer lines. The injected beam parameters need to be well under control for luminosity performance, machine protection and operational efficiency. Small fractions of beam loss on the transfer line collimation system create showers which can trigger the sensitive LHC beam loss monitor system nearby and cause a beam abort during filling. The stability of the transfer line trajectory through the collimators is particularly critical in this respect. This paper will report on the transfer line trajectory stability during the proton run in 2011, correlations with injection losses, correction frequency and the most likely sources for the observed oscillations.

  6. Hierarchical control of electron-transfer

    DEFF Research Database (Denmark)

    Westerhoff, Hans V.; Jensen, Peter Ruhdal; Egger, Louis;

    1997-01-01

    In this chapter the role of electron transfer in determining the behaviour of the ATP synthesising enzyme in E. coli is analysed. It is concluded that the latter enzyme lacks control because of special properties of the electron transfer components. These properties range from absence of a strong...... back pressure by the protonmotive force on the rate of electron transfer to hierarchical regulation of the expression of the gens that encode the electron transfer proteins as a response to changes in the bioenergetic properties of the cell.The discussion uses Hierarchical Control Analysis...

  7. The Knowledge Dimension of Production Transfer

    DEFF Research Database (Denmark)

    Riis, Jens Ove; Wæhrens, Brian Vejrum; Madsen, Erik Skov

    2010-01-01

    of the transfer process, and a distinction between the sending and the receiving orga­nizational unit. A method for capturing the tacit knowledge embedded in a pro­duction job has been developed and tested. The framework and the method will provide a basis for preparing a master plan for knowledge transfer......Empirical studies in three industrial companies have revealed that even companies with many years of experience in production transfer tend to focus attention on planning the physical transfer and on the explicit knowledge associated with normal production. They are uncertain about capturing, trans...

  8. Changing patterns of US arms transfers

    Energy Technology Data Exchange (ETDEWEB)

    Salomone, M.D.

    1985-01-01

    The thesis has three purposes. First is to explore the changing patterns of US arms transfers from Fiscal Year 1950 (FY 1950) through Fiscal Year 1980 (FY 1980). Second, is to describe and assess the decision-making process for arms transfers within the US Government. Third is to examine and critique the conventional wisdom concerning US arms transfers, to support that wisdom, or to offer an alternate empirically supported view. The conventional wisdom about US arms transfer is that they have been rising at an alarming rate, and that this is the result of an arms transfer decision-making process which is out of control. This belief is founded on an empirically based proposition that arms transfers have been rising at an alarming rate. However, this proposition has never been empirically validated. To explore this conventional wisdom, the author establishes the historical, political and defense policy contexts for US arms transfers over the period FY 1950 through FY 1980. The author critiques the conventional wisdom about US arms transfers, analyzes the many ways that arms transfers have been measured, and explores the impediments to accurate measurement and assessment of the phenomenon.

  9. Electrostatic transfer of epitaxial graphene to glass.

    Energy Technology Data Exchange (ETDEWEB)

    Ohta, Taisuke; Pan, Wei; Howell, Stephen Wayne; Biedermann, Laura Butler; Beechem Iii, Thomas Edwin; Ross, Anthony Joseph, III

    2010-12-01

    We report on a scalable electrostatic process to transfer epitaxial graphene to arbitrary glass substrates, including Pyrex and Zerodur. This transfer process could enable wafer-level integration of graphene with structured and electronically-active substrates such as MEMS and CMOS. We will describe the electrostatic transfer method and will compare the properties of the transferred graphene with nominally-equivalent 'as-grown' epitaxial graphene on SiC. The electronic properties of the graphene will be measured using magnetoresistive, four-probe, and graphene field effect transistor geometries [1]. To begin, high-quality epitaxial graphene (mobility 14,000 cm2/Vs and domains >100 {micro}m2) is grown on SiC in an argon-mediated environment [2,3]. The electrostatic transfer then takes place through the application of a large electric field between the donor graphene sample (anode) and the heated acceptor glass substrate (cathode). Using this electrostatic technique, both patterned few-layer graphene from SiC(000-1) and chip-scale monolayer graphene from SiC(0001) are transferred to Pyrex and Zerodur substrates. Subsequent examination of the transferred graphene by Raman spectroscopy confirms that the graphene can be transferred without inducing defects. Furthermore, the strain inherent in epitaxial graphene on SiC(0001) is found to be partially relaxed after the transfer to the glass substrates.

  10. Transfer Matrix for Fibonacci Dielectric Superlattice

    Institute of Scientific and Technical Information of China (English)

    蔡祥宝

    2001-01-01

    The transfer matrices, which transfer the amplitudes of the electric fields of second- and third-harmonic waves from one side of the interface to the other, are defined for layers joined coherently, and the total transfer matrices for several sequential interfaces can be simply obtained by multiplication of the matrices. Using the transfer matrix method, the interacting processes of second- and third-harmonic waves in a one-dimensional finite Fibonacci dielectric superlattice are investigated. Applying the numerical procedure described in this letter, the dependence of the second- and third-harmonic fields on sample thickness is obtained. The numerical results agree with the quasi-phase-matching theory.

  11. TRANSFER PRICES: MECHANISMS, METHODS AND INTERNATIONAL APPROACHES

    Directory of Open Access Journals (Sweden)

    Pop Cosmina

    2008-05-01

    Full Text Available Transfer prices are considered the prices paid for the goods or services in a cross-border transaction between affiliates companies, often significant reduced or increased in order to avoid the higher imposing rates from one jurisdiction. Presently, over 60% of cross-border transfers are represented by intra-group transfers. The paper presents the variety of methods and mechanisms used by the companies to transfer the funds from one tax jurisdiction to another in order to avoid over taxation.

  12. Abstraction and underspecification in semantic transfer

    OpenAIRE

    Abb, Bernd; Buschbeck-Wolf, Bianka; Tschernitschek, Christel

    1996-01-01

    This paper introduces the semantic transfer approach MinT (Minimal Transfer) that has been developed in the speech-to-speech MT system VERBMOBIL. As a unification-based and lexicalist semantic transfer model, it relies on some central ideas of the MRS-based transfer approach outlined in [Copestake et al., 1995]. It differs, however, from the latter in certain aspects: in MinT, the idea of abstraction and underspecification is worked out in much more detail and has been applied to a variety of...

  13. Charge-transfer with graphene and nanotubes

    Directory of Open Access Journals (Sweden)

    C.N.R. Rao

    2010-09-01

    Full Text Available Charge-transfer between electron–donor and –acceptor molecules is a widely studied subject of great chemical interest. Some of the charge-transfer compounds in solid state exhibit novel electronic properties. In the last two to three years, occurrence of molecular charge-transfer involving single-walled carbon nanotubes (SWNTs and graphene has been demonstrated. This interaction gives rise to significant changes in the electronic properties of these nanocarbons. We examine charge-transfer phenomenon in graphene and SWNTs in this article in view of its potential utility in device applications.

  14. Boiling heat transfer modern developments and advances

    CERN Document Server

    Lahey, Jr, RT

    2013-01-01

    This volume covers the modern developments in boiling heat transfer and two-phase flow, and is intended to provide industrial, government and academic researchers with state-of-the-art research findings in the area of multiphase flow and heat transfer technology. Special attention is given to technology transfer, indicating how recent significant results may be used for practical applications. The chapters give detailed technical material that will be useful to engineers and scientists who work in the field of multiphase flow and heat transfer. The authors of all chapters are members of the

  15. Transfer Pricing in the European Union

    Directory of Open Access Journals (Sweden)

    Gheorghe MATEI

    2011-04-01

    Full Text Available The transfer pricing mechanism is a tool commonly used to transfer the tax base from countries with high taxation in countries with low taxation. In the European Union, this financial operations generate significant tax revenue losses. In an attempt to limit the handling of corporate tax systems, many public authorities have introduced regulations on transfer pricing, but the effectiveness of these rules has proved limited, and they contributed to the increasing complexity of tax laws and to the appearance of additional costs for companies. A solution to the solving of the transfer pricing problem in the European Union is represented by the introduction of the common consolidated corporate tax base.

  16. Heat transfer models in narrow gap

    International Nuclear Information System (INIS)

    For severe accident assessment in a light water reactor (LWR), heat transfer models in a narrow annular gap between the overheated core debris and the reactor pressure vessel (RPV) are important to evaluate the integrity of RPV and emergency procedures. Some heat transfer models have been proposed as gap cooling CHF (critical heat flux) but the effects of superheat on the heat transfer surface were not taken into account. This paper presents the effects of superheat based on existing data and heat transfer models in a narrow gap. (author)

  17. Risk transfer solutions for the insurance industry

    Directory of Open Access Journals (Sweden)

    Njegomir Vladimir

    2009-01-01

    Full Text Available The paper focuses on the traditional and alternative mechanisms for insurance risk transfer that are available to global as well as to domestic insurance companies. The findings suggest that traditional insurance risk transfer solutions available to insurance industry nowadays will be predominant in the foreseeable future but the increasing role of alternative solutions is to be expected as the complementary rather than supplementary solution to traditional transfer. Additionally, findings suggest that it is reasonable to expect that future development of risk transfer solutions in Serbia will follow the path that has been passed by global insurance industry.

  18. Information transfer through quantum channels

    International Nuclear Information System (INIS)

    This PhD thesis represents work done between Aug. 2003 and Dec. 2006 in Reinhard F. Werner's quantum information theory group at Technische Universitaet Braunschweig, and Artur Ekert's Centre for Quantum Computation at the University of Cambridge. My thesis falls into the field of abstract quantum information theory. This work investigates both fundamental properties of quantum channels and their asymptotic capacities for classical as well as quantum information transfer. Stinespring's theorem is the basic structure theorem for quantum channels. It implies that every quantum channel can be represented as a unitary evolution on an enlarged system. In Ch. 3 we present a continuity theorem for Stinespring's representation: two quantum channels are similar if and only if it is possible to find unitary implementations that are likewise similar, with dimension-independent norm bounds. The continuity theorem allows to derive a formulation of the information-disturbance tradeoff in terms of quantum channels, and a continuity estimate for the no-broadcasting principle. In Ch. 4 we then apply the continuity theorem to give a strengthened no-go proof for quantum bit commitment, an important cryptographic primitive. This result also provides a natural characterization of those protocols that fall outside the standard setting of unconditional security, and thus may allow secure bit commitment. We present a new such protocol whose security relies on decoherence in the receiver's lab. Ch. 5 reviews the capacities of quantum channels for the transfer of both classical and quantum information, and investigates several variations in the notion of channel capacity. Memory effects are then investigated in detail in Ch. 6. We advertise a model which is sufficiently general to encompass all causal automata: every quantum process in which the outputs up to any given time t do not depend on the inputs at times t'>t can be represented as a concatenated memory channel. We then explain how

  19. Information transfer through quantum channels

    Energy Technology Data Exchange (ETDEWEB)

    Kretschmann, D.

    2007-03-12

    This PhD thesis represents work done between Aug. 2003 and Dec. 2006 in Reinhard F. Werner's quantum information theory group at Technische Universitaet Braunschweig, and Artur Ekert's Centre for Quantum Computation at the University of Cambridge. My thesis falls into the field of abstract quantum information theory. This work investigates both fundamental properties of quantum channels and their asymptotic capacities for classical as well as quantum information transfer. Stinespring's theorem is the basic structure theorem for quantum channels. It implies that every quantum channel can be represented as a unitary evolution on an enlarged system. In Ch. 3 we present a continuity theorem for Stinespring's representation: two quantum channels are similar if and only if it is possible to find unitary implementations that are likewise similar, with dimension-independent norm bounds. The continuity theorem allows to derive a formulation of the information-disturbance tradeoff in terms of quantum channels, and a continuity estimate for the no-broadcasting principle. In Ch. 4 we then apply the continuity theorem to give a strengthened no-go proof for quantum bit commitment, an important cryptographic primitive. This result also provides a natural characterization of those protocols that fall outside the standard setting of unconditional security, and thus may allow secure bit commitment. We present a new such protocol whose security relies on decoherence in the receiver's lab. Ch. 5 reviews the capacities of quantum channels for the transfer of both classical and quantum information, and investigates several variations in the notion of channel capacity. Memory effects are then investigated in detail in Ch. 6. We advertise a model which is sufficiently general to encompass all causal automata: every quantum process in which the outputs up to any given time t do not depend on the inputs at times t'>t can be represented as a concatenated memory

  20. Enigmatic Gratuitous Induction of the Covalent Flavoprotein Vanillyl-Alcohol Oxidase in Penicillium simplicissimum

    NARCIS (Netherlands)

    Fraaije, Marco W.; Pikkemaat, Mariël; Berkel, Willem J.H. van

    1997-01-01

    When Penicillium simplicissimum is grown on veratryl alcohol, anisyl alcohol, or 4-(methoxymethyl)phenol, an intracellular covalent flavin-containing vanillyl-alcohol oxidase is induced. The induction is highest (up to 5% of total protein) during the growth phase. In addition to vanillyl-alcohol oxi

  1. Fostering transfer of websearchers’ evaluation skills: a field test of two transfer theories

    NARCIS (Netherlands)

    Walraven, Amber; Brand-Gruwel, Saskia; Boshuizen, Els

    2010-01-01

    Walraven, A., Brand-Gruwel, S., & Boshuizen, H. P. A. (2010). Fostering transfer of web searchers’ evaluation skills: A field test of two transfer theories. Computers in Human Behavior, 26, 716-728.

  2. When absorptive capacity meets technology transfer : transferring of an e-learning system to Russia

    OpenAIRE

    2005-01-01

    This master thesis aims at using the theoretical framework of absorptive capacity as suggested by Cohen and Levinthal (1990) to account for the underlying dimensions critical in a technology transfer process. Technology transfer is a complicated and dynamic process in which technology moves between the transferring partners. The nature of the technology and the capacities of the involved organisations appear to be important in accounting for the transfer. The research applies the use of absor...

  3. Heat Transfer in Complex Fluids

    Energy Technology Data Exchange (ETDEWEB)

    Mehrdad Massoudi

    2012-01-01

    fluids show Newtonian (linear) behavior for a given range of parameters or geometries; there are many empirical or semi-empirical constitutive equations suggested for these fluids. There have also been many non-linear constitutive relations which have been derived based on the techniques of continuum mechanics. The non-linearities oftentimes appear due to higher gradient terms or time derivatives. When thermal and or chemical effects are also important, the (coupled) momentum and energy equations can give rise to a variety of interesting problems, such as instability, for example the phenomenon of double-diffusive convection in a fluid layer. In Conclusion, we have studied the flow of a compressible (density gradient type) non-linear fluid down an inclined plane, subject to radiation boundary condition. The heat transfer is also considered where a source term, similar to the Arrhenius type reaction, is included. The non-dimensional forms of the equations are solved numerically and the competing effects of conduction, dissipation, heat generation and radiation are discussed. It is observed that the velocity increases rapidly in the region near the inclined surface and is slower in the region near the free surface. Since R{sub 7} is a measure of the heat generation due to chemical reaction, when the reaction is frozen (R{sub 7}=0.0) the temperature distributions would depend only on R{sub 1}, and R{sub 2}, representing the effects of the pressure force developed in the material due to the distribution, R{sub 3} and R{sub 4} viscous dissipation, R{sub 5} the normal stress coefficient, R{sub 6} the measure of the emissivity of the particles to the thermal conductivity, etc. When the flow is not frozen (RP{sub 7} > 0) the temperature inside the flow domain is much higher than those at the inclined and free surfaces. As a result, heat is transferred away from the flow toward both the inclined surface and the free surface with a rate that increases as R{sub 7} increases. For a

  4. One-way radiative transfer

    Science.gov (United States)

    González-Rodríguez, Pedro; Ilan, Boaz; Kim, Arnold D.

    2016-06-01

    We introduce the one-way radiative transfer equation (RTE) for modeling the transmission of a light beam incident normally on a slab composed of a uniform forward-peaked scattering medium. Unlike the RTE, which is formulated as a boundary value problem, the one-way RTE is formulated as an initial value problem. Consequently, the one-way RTE is much easier to solve. We discuss the relation of the one-way RTE to the Fokker-Planck, small-angle, and Fermi pencil beam approximations. Then, we validate the one-way RTE through systematic comparisons with RTE simulations for both the Henyey-Greenstein and screened Rutherford scattering phase functions over a broad range of albedo, anisotropy factor, optical thickness, and refractive index values. We find that the one-way RTE gives very good approximations for a broad range of optical property values for thin to moderately thick media that have moderately to sharply forward-peaked scattering. Specifically, we show that the error made by the one-way RTE decreases monotonically as the anisotropic factor increases and as the albedo increases. On the other hand, the error increases monotonically as the optical thickness increases and the refractive index mismatch at the boundary increases.

  5. Proton transfer reaction - mass spectrometry

    International Nuclear Information System (INIS)

    Proton transfer reaction mass spectrometry (PTR-MS) provides on-line monitoring of volatile organic compounds (VOCs) with a low detection threshold and a fast response time. Commercially available set-ups are usually based on quadrupole analysers but recently new instruments based on time-of-flight (PTR-ToF-MS) analysers have been proposed and commercialized. PTR-MS has been successfully applied to a variety of fields including environmental science, food science and technology, plant physiology and medical science. Many new challenges arise from the newly available PTR-ToF-MS instruments, ranging from mass calibration and absolute VOC concentration determination to data mining and sample classification. This thesis addresses some of these problems in a coherent framework. Moreover, relevant applications in food science and technology are presented. It includes twelve papers published in peer reviewed journals. Some of them address methodological issues regarding PTR-ToF-MS; the others contain applicative studies of PTR-ToF-MS to food science and technology. Among them, there are the first two published applications of PTR-ToF-MS in this field. (author)

  6. Technology transfer to the broader economy

    Science.gov (United States)

    Dyer, Gordon; Clark, Robert

    1992-01-01

    Approaches to the transfer of government-funded civil space technology to the broader commercial economy were addressed by Working Panel no. 4. Some of the problems related to current strategies for technology transfer and recommendations for new approaches are described in outline form.

  7. Heat Transfer in a Thermoacoustic Process

    Science.gov (United States)

    Beke, Tamas

    2012-01-01

    Thermoacoustic instability is defined as the excitation of acoustic modes in chambers with heat sources due to the coupling between acoustic perturbations and unsteady heat addition. The major objective of this paper is to achieve accurate theoretical results in a thermoacoustic heat transfer process. We carry out a detailed heat transfer analysis…

  8. Non-surgical embryo transfer in pigs

    NARCIS (Netherlands)

    Hazeleger, W.

    1999-01-01

    Embryo transfer in pigs has been performed surgically for a long time. However, a less invasive, non-surgical, procedure of embryo transfer could be a valuable tool for research (to study embryo survival and embryo-uterus interactions) and practical applications (export, prevention of disease transm

  9. Heat transfer in the Knudsen layer

    Science.gov (United States)

    Sharipov, Felix

    2004-06-01

    A concept of the surface heat conductivity determining a heat transfer in the Knudsen layer was introduced. It has the same order with respect to the Knudsen number as the bulk heat transfer and must be taken into account in practical calculations. Using the Onsager principle the coefficient of the surface heat conductivity was related to the thermal slip coefficient.

  10. A case of technology transfer in Macedonia

    Directory of Open Access Journals (Sweden)

    Nattacia Dabescki

    2014-11-01

    Full Text Available As a process of transferring skills, knowledge, technologies, methods of manufacturing and facilities among organizations, the transfer of technology is instrumental for boosting the economy through creation of competitive products, new jobs and a better quality of life. The stagnant environment for technology transfers in Macedonia in the post-privatisation era is a result of a combination of factors. Among them is the outdated educational system that does not boost entrepreneurial spirit and innovation thinking. Main purpose of this paper is to examine the current status, conditions, anomalies and challenges for technology transfer in the Republic of Macedonia, as well as the potential for development and possibilities for improvement of the process. Through a lens of the technology transfer paradigm, this exploratory study will present a case in which the Foundation Business Start-up Centre in Macedonia, as a technology transfer agent provided links and cooperative platform for creation of new technologies and innovations within the local SME ecosystem. The focus will be on a couple of initiatives for technology development and transfer in a domestic context. Results from the process of implementation of these initiatives will be discussed, along with their stimulating impact on the environment for technology transfer.

  11. Trades to Academic Transfer. Special Report

    Science.gov (United States)

    McQuarrie, Fiona

    2012-01-01

    In recent years, there has been increased interest within British Columbia in the issue of whether or how trades qualifications might transfer into academic post-secondary programs. Some BC institutions have already started, or will be starting, programs which incorporate this form of transfer credit. Colleagues at British Columbia Council on…

  12. Transferring the Learning of Teaching Models.

    Science.gov (United States)

    Martin, William C.

    1981-01-01

    Ascertains the amount of transfer which takes place between on-campus training in teaching models and field application. Three models of teaching were selected--inquiry; role-playing; and synectics. The results illustrated that a preservice social studies program of model-based instruction fosters a decidedly high potential for transferring the…

  13. Energy transfer phenomena in lead sulphate

    NARCIS (Netherlands)

    Blasse, G.

    1975-01-01

    It is shown that lead sulphate, PbSO4, shows Pb2+ emission with a large Stokes shift. Energy transfer has been observed from the Pb2+ ions to several luminescent centres, viz., tungstate, molybdate, vanadate and rare earths. No transfer occurs to the Pr3+ ion.

  14. Guidelines for Transferring Residential Courses into Web

    Science.gov (United States)

    Tüzün, Hakan; Çinar, Murat

    2016-01-01

    This study shared unique design experiences by examining the process of transferring residential courses to the Web, and proposed a design model for individuals who want to transfer their courses into this environment. The formative research method was used in the study, and two project teams' processes of putting courses, which were being taught…

  15. Excited state Intramolecular Proton Transfer in Anthralin

    DEFF Research Database (Denmark)

    Møller, Søren; Andersen, Kristine B.; Spanget-Larsen, Jens;

    1998-01-01

    Quantum chemical calculations performed on anthralin (1,8-dihydroxy-9(10H)-anthracenone) predict the possibility of an excited-state intramolecular proton transfer process. Fluorescence excitation and emission spectra of the compound dissolved in n-hexane at ambient temperature results in an......, associated with an excited-state intramolecular proton transfer process....

  16. 5 CFR 315.501 - Transfer.

    Science.gov (United States)

    2010-01-01

    ... Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CAREER AND CAREER-CONDITIONAL EMPLOYMENT Career or Career-Conditional Employment by Transfer § 315.501 Transfer. Subject to part 335 of... service of a single workday, a current career or career-conditional employee of another agency....

  17. 78 FR 63235 - Tank Vessel Oil Transfers

    Science.gov (United States)

    2013-10-23

    ... notice regarding our public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316... SECURITY Coast Guard Tank Vessel Oil Transfers AGENCY: Coast Guard, DHS. ACTION: Notice and request for... spills in oil transfer operations from or to a tank vessel, and requests public input on measures...

  18. 78 FR 71633 - Tank Vessel Oil Transfers

    Science.gov (United States)

    2013-11-29

    ... document reopens the comment period on the Coast Guard's October 23, 2013, notice (78 FR 63235) by an... SECURITY Coast Guard Tank Vessel Oil Transfers AGENCY: Coast Guard, DHS. ACTION: Notice; reopening of..., concerning new measures to reduce the risks of oil spills in oil transfer operations from or to a tank...

  19. Reducing Income Transfers to Refugee Immigrants

    DEFF Research Database (Denmark)

    Rosholm, Michael; Vejlin, Rune Majlund

    2010-01-01

    We estimate the effect of lowering income transfers to refugee immigrants in Denmark - labeled start-help - using a competing risk framework. Refugee immigrants obtaining residence permit before July 2002 received larger income transfers than those who obtained their residence permit later...

  20. 42 CFR 73.16 - Transfers.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Transfers. 73.16 Section 73.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION, LICENSING SELECT AGENTS... select agent or toxin may only be transferred to individuals or entities registered to possess, use,...

  1. Is Utility Transferable? A Revealed Preference Analysis

    NARCIS (Netherlands)

    Cherchye, L.J.H.; Demuynck, T.; de Rock, B.

    2011-01-01

    We provide a revealed preference analysis of the transferable utility hypothesis, which is widely used in economic models. First, we establish revealed preference conditions that must be satisfied for observed group behavior to be consistent with Pareto efficiency under transferable utility. Next, w

  2. Oligopoly Games With and Without Transferable Technologies

    NARCIS (Netherlands)

    Norde, H.W.; Pham Do, K.H.; Tijs, S.H.

    2000-01-01

    In this paper standard oligopolies are interpreted in two ways, namely as oligopolies without transferable technologies and as oligopolies with transferable technologies.From a cooperative point of view this leads to two different classes of cooperative games.We show that cooperative oligopoly games

  3. Retirement Migration and Interstate Income Transfers.

    Science.gov (United States)

    Longino, Charles F., Jr.; Crown, William H.

    1990-01-01

    Examined transfer of income from state to state as result of elderly migration. Data from 1980 census microdata files revealed that billions of dollars are transferred between states each year. Used 1980-81 Consumer Expenditure Interview Survey to estimate consumption patterns of typical migrant household. Findings are discussed in context of…

  4. Wiener Filter Estimation of Transfer Functions

    Science.gov (United States)

    Kessel, Robert

    2004-01-01

    The use of a Wiener filter estimate for the linear transfer function can significantly improve the description of behavioral dynamics. This report presents a two-pass, Monte-Carlo-based algorithm that is well suited to repeated-trials local average measurements. The Wiener filter transfer functions strongly suppress noise artifacts as well as…

  5. A Simple Experiment for Mass Transfer.

    Science.gov (United States)

    Rodriguez, Jesus M.; Henriquez, Vicente; Macias-Machin, Agustin

    1998-01-01

    Presents an experiment in which students use laboratory data to calculate the interphase mass transfer coefficient for a fluid passed over a sphere and obtain correlations for solid-gas mass transfer. Students develop a realistic mathematical model to describe the sublimation process. (DDR)

  6. How We Make Mass Transfer Seem Difficult.

    Science.gov (United States)

    Cussler, E. L.

    1984-01-01

    Indicates that teaching of mass transfer can be improved by: (1) using a single, simple definition of mass transfer coefficients; (2) altering use of analogies; and (3) repeatedly stressing differences between mathematical models used for chemical reactions and the actual chemistry of these reactions. Examples for undergraduate/graduate courses…

  7. Taxation, Transfer Income and Stock Market Participation

    DEFF Research Database (Denmark)

    Fischer, Marcel; Astrup Jensen, Bjarne

    2015-01-01

    This article studies the impact of a redistributive tax system on consumption, portfolio decisions, and asset prices in a dynamic general equilibrium model. Poorer agents, which receive more in transfers than they pay in taxes, optimally reduce their exposure to equity, because the transfer income...

  8. Heat transfer from humans wearing clothing

    NARCIS (Netherlands)

    Lotens, W.A.

    1993-01-01

    In this monograph the effects of clothing on human heat transfer are described. The description is based on the physics of heat and mass transfer, depending on the design of the clothing, the climate, and the activity of the wearer. The resulting model has been stepwise implemented in computer progr

  9. Judging The International Transfer Of Technology

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2000-01-01

    International transfer of technology is a widely discussed area in the scientific literature. Although many different factors are discussed in the literature that affect the transfer of technology, it is not clear how to judge the performance of companies involved in international technology transfe

  10. Interactive Joint Transfer of Energy and Information

    DEFF Research Database (Denmark)

    Popovski, Petar; Fouladgar, A. M.; Simeone, Osvaldo

    2013-01-01

    In some communication networks, such as passive RFID systems, the energy used to transfer information between a sender and a recipient can be reused for successive communication tasks. In fact, from known results in physics, any system that exchanges information via the transfer of given physical...

  11. Long Term Transfer Effect of Metaphoric Allusion.

    Science.gov (United States)

    Hayes, David A.; Mateja, John A.

    A study was conducted to investigate the long term transfer effect of metaphoric allusion used to clarify unfamiliar subject matter. Forty-nine high school students were given unfamiliar prose materials variously augmented by metaphoric allusion. The subjects' immediate performance on a transfer task was compared to their performance on an…

  12. Boiling heat transfer with acoustic cavitation

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The effects of acoustic cavitation and nanometer granule on boiling heat transfer of horizontal circular copper tube are investigated experimentally and theoretically using acetone as the working fluid according to the boiling procedure. The results show that heat transfer can be enhanced or weakened by generation of the cavitation bubble or addition of the nanometer granules, respectively. The mechanisms of the effects are analyzed.

  13. Preventing Maritime Transfer of Toxigenic Vibrio cholerae

    Science.gov (United States)

    Slaten, Douglas D.; Marano, Nina; Tappero, Jordan W.; Wellman, Michael; Albert, Ryan J.; Hill, Vincent R.; Espey, David; Handzel, Thomas; Henry, Ariel; Tauxe, Robert V.

    2012-01-01

    Organisms, including Vibrio cholerae, can be transferred between harbors in the ballast water of ships. Zones in the Caribbean region where distance from shore and water depth meet International Maritime Organization guidelines for ballast water exchange are extremely limited. Use of ballast water treatment systems could mitigate the risk for organism transfer. PMID:23017338

  14. Dynamic Heat Transfer Model of Refrigerated Foodstuff

    DEFF Research Database (Denmark)

    Cai, Junping; Risum, Jørgen; Thybo, Claus

    2006-01-01

    their temperature relation. This paper discusses the dynamic heat transfer model of foodstuff inside the display cabinet, one-dimensional dynamic model is developed, and the Explicit Finite Difference Method is applied, to handle the unsteady heat transfer problem with phase change, as well as time varying boundary...

  15. Horizontal gene transfer in the phytosphere

    NARCIS (Netherlands)

    Elsas, van J.D.; Turner, S.; Bailey, M.J.

    2003-01-01

    Here, the ecological aspects of gene transfer processes between bacteria in the phytosphere are examined in the context of emerging evidence for the dominant role that horizontal gene transfer (HGT) has played in the evolutionary shaping of bacterial communities. Moreover, the impact of the putative

  16. Targeting Low-Energy Ballistic Lunar Transfers

    Science.gov (United States)

    Parker, Jeffrey S.

    2010-01-01

    Numerous low-energy ballistic transfers exist between the Earth and Moon that require less fuel than conventional transfers, but require three or more months of transfer time. An entirely ballistic lunar transfer departs the Earth from a particular declination at some time in order to arrive at the Moon at a given time along a desirable approach. Maneuvers may be added to the trajectory in order to adjust the Earth departure to meet mission requirements. In this paper, we characterize the (Delta)V cost required to adjust a low-energy ballistic lunar transfer such that a spacecraft may depart the Earth at a desirable declination, e.g., 28.5(white bullet), on a designated date. This study identifies the optimal locations to place one or two maneuvers along a transfer to minimize the (Delta)V cost of the transfer. One practical application of this study is to characterize the launch period for a mission that aims to launch from a particular launch site, such as Cape Canaveral, Florida, and arrive at a particular orbit at the Moon on a given date using a three-month low-energy transfer.

  17. Automatic fuel transfer apparatus and method

    Energy Technology Data Exchange (ETDEWEB)

    Howard, N.C.; Lussier, M.C.; Miller, K.R.

    1984-01-24

    In a nucler reactor containment structure, a fuel transfer arrangement is described which includes a bridge, trolley, and grapple, each of the latter having a position sensor mounted thereon, and control means for determining the position of bridge, trolley, and grapple in response to signals from said position sensors, whereby fuel assemblies may be transferred between locations in the containment structure.

  18. An integrated approach towards technology transfer

    NARCIS (Netherlands)

    Wal, L.F. van der; Eldering, C.J.J.; Putten, N.J. van

    2010-01-01

    In 2001 the European Space Agency (ESA), the Dutch Ministry of Economic Affairs and the Netherlands Organisation of applied scientific research TNO initiated the Dutch Technology Transfer Programme (DTTP). Since then, 'technology transfer' has been a relevant part of Dutch space policy. The DTTP aim

  19. Radiative transfer and molecular data for astrochemistry

    NARCIS (Netherlands)

    Tak, Floris van der

    2011-01-01

    The estimation of molecular abundances in interstellar clouds from spectroscopic observations requires radiative transfer calculations, which depend on basic molecular input data. This paper reviews recent developments in the fields of molecular data and radiative transfer. The first part is an over

  20. Knowledge Transfer in International Manufacturing Networks

    DEFF Research Database (Denmark)

    Madsen, Erik Skov

    and the paper suggests how the transfer of tacit knowledge, in particular, can be improved. The paper discusses two dramatic shifts in organizational settings, i.e. from operations management to project management in the sending unit before a transfer and the reverse in the receiving unit after...

  1. Transfer mechanism of temoporfin between liposomal membranes.

    Science.gov (United States)

    Hefesha, Hossam; Loew, Stephan; Liu, Xiangli; May, Sylvio; Fahr, Alfred

    2011-03-30

    The transfer kinetics of temoporfin, a classic photosensitizer, was analyzed by investigating the influence of total lipid content, temperature, as well as charge, acyl chain length, and saturation of the lipids in donor vesicles using a mini ion exchange column technique. The obtained results are consistent with an apparent first order kinetics in which the transfer proceeds through both liposome collisions and through the aqueous phase. We present a corresponding theoretical model that accounts for the detailed distribution of drug molecules in donor and acceptor liposomes and predicts the transfer rates as a function of drug concentration and number of donor and acceptor liposomes. The experimentally observed transfer rates depended strongly on the temperature and comply with the Arrhenius equation. Thermodynamic calculations indicate the transfer process to be entropically controlled. In terms of the charge of donor liposomes, positively charged liposomes showed transfer rates faster than negatively charged liposomes whereas the maximum amount transferred was almost the same. A more rigid structure of the donor liposomes increases the transfer rate of temoporfin, which is caused by expelling the drug from the membrane interior, as proposed in former work. In summary, our combined theoretical/experimental approach offers a systematic way to study the mechanism of drug release from liposome-based delivery systems.

  2. Free Trade, Customs Unions, and Transfers

    OpenAIRE

    Hideo Konishi; Carsten Kowalczyk; Tomas Sjostrom

    2003-01-01

    All countries would agree to immediate global free trade if countries were compensated for any terms-of-trade losses with transfers from countries whose terms-of-trade improve, and if customs unions were required to have no effects on non-member countries. Global free trade with transfers is in the core of a Kemp-Wan-Grinols customs union game.

  3. Determinants of Transfer among Community College Students

    Science.gov (United States)

    Wood, J. Luke; Nevarez, Carlos; Hilton, Adriel A.

    2012-01-01

    The purpose of this study was to identify determinants of transfer. Accounting for variables in several domains (background, academic, social, environmental), this research was particularly interested in the effect of environment on transfer. Data employed in this study was derived from the Beginning Postsecondary Students Longitudinal Study (BPS:…

  4. Vibrational control of electron-transfer reactions: a feasibility study for the fast coherent transfer regime.

    Science.gov (United States)

    Antoniou, P; Ma, Z; Zhang, P; Beratan, D N; Skourtis, S S

    2015-12-14

    Molecular vibrations and electron-vibrational interactions are central to the control of biomolecular electron and energy-transfer rates. The vibrational control of molecular electron-transfer reactions by infrared pulses may enable the precise probing of electronic-vibrational interactions and of their roles in determining electron-transfer mechanisms. This type of electron-transfer rate control is advantageous because it does not alter the electronic state of the molecular electron-transfer system or irreversibly change its molecular structure. For bridge-mediated electron-transfer reactions, infrared (vibrational) excitation of the bridge linking the electron donor to the electron acceptor was suggested as being capable of influencing the electron-transfer rate by modulating the bridge-mediated donor-to-acceptor electronic coupling. This kind of electron-transfer experiment has been realized, demonstrating that bridge-mediated electron-transfer rates can be changed by exciting vibrational modes of the bridge. Here, we use simple models and ab initio computations to explore the physical constraints on one's ability to vibrationally perturb electron-transfer rates using infrared excitation. These constraints stem from the nature of molecular vibrational spectra, the strengths of the electron-vibrational coupling, and the interaction between molecular vibrations and infrared radiation. With these constraints in mind, we suggest parameter regimes and molecular architectures that may enhance the vibrational control of electron transfer for fast coherent electron-transfer reactions.

  5. Transfer Innovations Fund Updating Project. BC Council on Admissions and Transfer. Tourism Management Articulation

    Science.gov (United States)

    British Columbia Council on Admissions and Transfer, 2010

    2010-01-01

    In 2008, a number of changes were identified that expanded the scope of the updating required for Block Transfer for tourism management as follows: a new core curriculum for diploma programs; the need for expanded information on diploma to diploma transfer; and, a growing need for an expanded system of transfer identified in Campus 2020…

  6. Factors Affecting Training Transfer: Participants' Motivation to Transfer Training, Literature Review

    Science.gov (United States)

    Alawneh, Muhammad K.

    2008-01-01

    This article investigates factors that motivate participants in learning and training activities to transfer skills, knowledge and attitude from the learning setting to the workplace. Based on training transfer theories hypothesized by Holton (1996), one of the major theories that affect an organization's learning is motivation to transfer theory.…

  7. Near field heat transfer in superlattices

    Science.gov (United States)

    Esquivel-Sirvent, Raul

    2015-03-01

    I present a theoretical calculation of the near field heat transfer between super lattices made of alternative layers of both metallic and semiconducting materials. The calculation of the near field transfer requires the knowledge of the reflectivities, that are obtained by calculating the surface impedance of the super lattice. Depending on the periodicity of the lattice and the dielectric function of the materials the near field heat transfer can be modulated or engineered. Additional control on the heat transfer is achieved by introducing defects in the superlattice. The results are extended to include photonic hypercrystals that effectively behave like a hyperbolic metamaterial even in the near field (1), where the tuning of the heat transfer is modified by Partial Support from DGAPA-UNAM project IN 111214.

  8. Heat transfer coefficient of cryotop during freezing.

    Science.gov (United States)

    Li, W J; Zhou, X L; Wang, H S; Liu, B L; Dai, J J

    2013-01-01

    Cryotop is an efficient vitrification method for cryopreservation of oocytes. It has been widely used owing to its simple operation and high freezing rate. Recently, the heat transfer performance of cryotop was studied by numerical simulation in several studies. However, the range of heat transfer coefficient in the simulation is uncertain. In this study, the heat transfer coefficient for cryotop during freezing process was analyzed. The cooling rates of 40 percent ethylene glycol (EG) droplet in cryotop during freezing were measured by ultra-fast measurement system and calculated by numerical simulation at different value of heat transfer coefficient. Compared with the results obtained by two methods, the range of the heat transfer coefficient necessary for the numerical simulation of cryotop was determined, which is between 9000 W/(m(2)·K) and 10000 W/(m (2)·K).

  9. New course: "Introduction to knowledge transfer tools"

    CERN Multimedia

    2014-01-01

    The Knowledge Transfer group is now offering a half-day course that will give an introduction to intellectual property, contracts for knowledge transfer, and projects involving industry and other external partners.   The purpose of the course is to give the essential information about how one can secure ownership of inventions and to provide information on legal and contractual considerations when transferring knowledge and technology or when doing collaborative R&D. The course will also highlight some common pitfalls that should be avoided to increase the chances of successfully transferring knowledge and technology. In addition, the course will involve examples of real projects and challenges. The first session will take place the 19 May 2014. To enroll, please follow this link: “Introduction to knowledge transfer tools”.

  10. SWAMI II technology transfer plan

    International Nuclear Information System (INIS)

    Thousands of drums of radioactive/hazardous/mixed waste are currently stored at DOE sites throughout US; they are stored in warehouse facilities on an interim basis, pending final disposition. Recent emphasis on anticipated decommissioning of facilities indicates that many more drums of waste will be generated, requiring additional storage. Federal and state regulations dictate that hazardous waste covered by RCRA be inspected periodically for container degradation and to verify inventories. All known DOE waste storage facilities are currently inspected manually. A system to perform robotic inspection of waste drums is under development by the SRTC Robotics Group of WSRC; it is called the Stored Waste Autonomous Mobile Inspector (SWAMI). The first version, SWAMI I, was developed by the Savannah River Technology Center (SRTC) as a proof of principle system for autonomous inspection of drums in a warehouse. SWAMI I was based on the Transitions Research Corporation (TRC) HelpMate mobile robot. TRC modified the Helpmate to navigate in aisles of drums. SRTC added subsystems to SWAMI I to determine its position in open areas, read bar code labels on the drums up to three levels high, capture images of the drums and perform a radiation survey of the floor in the aisles. The radiation survey was based on SRTC patented technology first implemented on the Semi-Intelligent Mobile Observing Navigator (SIMON). The radiation survey is not essential for the inspection of drums, but is an option that can increase the utility and effectiveness of SWAMI in warehouses with radioactive and/or mixed waste. All the sensors on SWAMI I were fixed on the vehicle. From the success of SWAMI I, a second version, SWAMI II, was developed; it will be evaluated at Fernald and tested with two other mobile robots. Intent is to transfer the technology developed for SWAMI I and II to industry so that it can supply additional units for purchase for drum inspection

  11. Transferring alien genes to wheat

    International Nuclear Information System (INIS)

    In broad terms an alien gene can be considered to be any gene transferred to wheat from a related species. As described above by Maan (section 7D) the genus Triticum contains a broad range of species, some of which cross readily with the cultivated tetraploid (T. Turgidum L.) or hexaploid (T. aestivum L.) wheats, and others only with great difficulty. In addition, wheat will also cross with species in a number of other genera including Agropyron, Elymus, Elytrigia (=Agropyron), Haynaldia, Hordeum, and Secale (Riley and Kimber, 1966; Knobloch, 1968; Feldman and Sears, 1981). In discussing the Triticum and Aegilops spp., the classification by Kimber and Sears, section SA-I, above, will be followed. For the Agropyron and related species the classification described by Dewey (1983) will be used. To avoid confusion, in referring to the literature the designations used by the authors will be given, followed by the new designation. The wild relatives of wheat are adapted to a broad range of environments and carry a large reservoir of useful genes (Zohary et al., 1969; Kerber and Dyck, 1973; Brezhnev, 1977; Feldman and Sears, 1981; Limin and Fowler, 1981; Sharma et aI., 1981; McGuire and Dvorak, 1981). Initially they were considered to be primarily sources of disease resistance, but more recently they have been recognized as potential sources of genes for high protein, cold tolerance, salt tolerance, drought tolerance, lodging resistance, early maturity, and even yield. Extensive screening of the wild relatives of wheat needs to be done before their useful genes can be fully utilized

  12. Charge transfer in multicomponent oxides

    Science.gov (United States)

    Kohan, A. F.; Ceder, G.

    1998-02-01

    The transfer of charge between different ions in an oxide plays an essential role in the stability of these compounds. Since small variations in charge can introduce large changes in the total energy, a correct description of this phenomenon is critical. In this work, we show that the ionic charge in oxides can strongly depend on its atomic environment. A model to assign point charges to atoms as a function of their atomic environment has recently been proposed for binary alloys [C. Wolverton, A. Zunger, S. Froyen, and S.-H. Wei, Phys. Rev. B 54, 7843 (1996)] and proven to be very successful in screened solids such as semiconductors and metals. Here, we extend this formalism to multicomponent oxides and we assess its applicability. The simple point-charge model predicts a linear relation between the charge on an atom and the number of unlike neighbors, and between the net value of the charge and the Coulomb field at a given site. The applicability of this approach is tested in a large-supercell self-consistent tight-binding calculation for a random Zr-Ca-O alloy. The observed fluctuations of the ionic charge about the average linear behavior (as a function of the number of unlike neighbors) was larger than 0.25 electrons even when many shells of atomic neighbors were considered in the fit. This variation is significant since it can introduce large errors in the electrostatic energy. On the other hand, for small absolute values of the charge, the ionic charge varied linearly with the Coulomb field, in agreement with previous findings. However, for large Coulomb fields, this function saturates at the formal chemical charge.

  13. Risk-based analytical method transfer: application to large multi-product transfers.

    Science.gov (United States)

    Raska, Christina S; Bennett, Tony S; Goodberlet, Scott A

    2010-07-15

    As pharmaceutical companies adapt their business models, a new approach to analytical method transfer is needed to efficiently handle transfers of multiple products, associated with situations such as site consolidations/closures. Using the principles of risk management, a risk-based method transfer approach is described, which defines appropriate transfer activities based on a risk assessment of the methods and experience of the receiving unit. A key step in the process is detailed knowledge transfer from the transferring unit to the receiving unit. The amount of transfer testing required can be streamlined or eliminated on the basis of a number of factors, including method capability, receiving unit familiarity, and method past performance. PMID:20557030

  14. Symmetric charge transfer cross section of uranium

    International Nuclear Information System (INIS)

    Symmetric charge transfer cross section of uranium was calculated under consideration of reaction paths. In the charge transfer reaction a d3/2 electron in the U atom transfers into the d-electron site of U+(4I9/2) ion. The J value of the U atom produced after the reaction is 6, 5, 4 or 3, at impact energy below several tens eV, only resonant charge transfer in which the product atom is ground state (J=6) takes place. Therefore, the cross section is very small (4-5 x 10-15 cm2) compared with that considered so far. In the energy range of 100-1000eV the cross section increases with the impact energy because near resonant charge transfer in which an s-electron in the U atom transfers into the d-electron site of U+ ion. Charge transfer cross section between U+ in the first excited state (289 cm-1) and U in the ground state was also obtained. (author)

  15. File Transfer Algorithm for Autonomous Decentralized System

    Institute of Scientific and Technical Information of China (English)

    GUI Xun; TAN Yong-dong; Qian Qing-quan

    2008-01-01

    A file transfer algorithm based on ADP (autonomous decentralized protocol) was proposed to solve the problem that the ADS (autonomous decentralized system) middleware (NeXUS/Dlink) lacks of file transfer functions for Windows. The algorithm realizes the peer-to-peer file transfer, one-to-N inquiry/multi-response file transfer and one-to-N file distribution in the same data field based on communication patterns provided by the ADP. The peer-to-peer file transfer is implemented through a peer-to-peer communication path, one-to-N inquiry/multi-response file transfer and one-to-N file distribution are implemented through multicast commtmieation. In this algorithm, a file to be transferred is named with a GUID ( global unique identification), every data packet is marked with a sequence number, and file-receiving in parallel is implemented by caching DPOs (data processing objects) and multithread technologies. The algorithm is applied in a simulation system of the decentralized control platform, and the test results and long time stable mrming prove the feasibility of the algorithm.

  16. Excitation energy transfer in the photosystem I

    Energy Technology Data Exchange (ETDEWEB)

    Webber, Andrew N

    2012-09-25

    Photosystem I is a multimeric pigment protein complex in plants, green alage and cyanobacteria that functions in series with Photosystem II to use light energy to oxidize water and reduce carbon dioxide. The Photosystem I core complex contains 96 chlorophyll a molecules and 22 carotenoids that are involved in light harvesting and electron transfer. In eucaryotes, PSI also has a peripheral light harvesting complex I (LHCI). The role of specific chlorophylls in excitation and electron transfer are still unresolved. In particular, the role of so-called bridging chlorophylls, located between the bulk antenna and the core electron transfer chain, in the transfer of excitation energy to the reaction center are unknown. During the past funding period, site directed mutagenesis has been used to create mutants that effect the physical properties of these key chlorophylls, and to explore how this alters the function of the photosystem. Studying these mutants using ultrafast absorption spectroscopy has led to a better understanding of the process by which excitation energy is transferred from the antenna chlorophylls to the electron transfer chain chlorophylls, and what the role of connecting chlorophylls and A_0 chlorophylls is in this process. We have also used these mutants to investigate whch of the central group of six chlorophylls are involved in the primary steps of charge separation and electron transfer.

  17. Transition boiling heat transfer during reflooding transients

    International Nuclear Information System (INIS)

    Transition boiling heat transfer is characterized by a heat flux which declines as the heater wall temperature increases. Steady state transition boiling is also characterized by alternate periods of high and low heat transfer caused by intermittent wetting of the heated surface. In flow boiling, the reason for intermittent wetting depends on the volume fraction of vapor present. At high vapor volume fractions, annular flow exists during what is generally called the nucleate boiling region, and a thin liquid film is present on the surface. The remainder of the passage is filled with vapor carrying entrained droplets. Above the nucleate boiling region there is no liquid film, and heat is transferred to droplet-laden vapor. In the narrow transition boiling region between nucleate boiling and heat transfer to steam, the liquid film is present only part of the time. The intermittent wetting produces significant wall temperature oscillations. Recent phenomenologically based modeling of steady state transition boiling heat transfer at high vapor fractions has been successful in predicting the magnitude of both temperature oscillations and heat transfer rates. After a brief review of the steady state model, this note shows how the results of the steady state analysis for vertical surfaces may be used to obtain heat transfer rates during reflooding transients

  18. Radiative heat transfer in porous uranium dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, S.L. [Texas A and M Univ., College Station, TX (United States)

    1992-12-01

    Due to low thermal conductivity and high emissivity of UO{sub 2}, it has been suggested that radiative heat transfer may play a significant role in heat transfer through pores of UO{sub 2} fuel. This possibility was computationally investigated and contribution of radiative heat transfer within pores to overall heat transport in porous UO{sub 2} quantified. A repeating unit cell was developed to model approximately a porous UO{sub 2} fuel system, and the heat transfer through unit cells representing a wide variety of fuel conditions was calculated using a finite element computer program. Conduction through solid fuel matrix as wekk as pore gas, and radiative exchange at pore surface was incorporated. A variety of pore compositions were investigated: porosity, pore size, shape and orientation, temperature, and temperature gradient. Calculations were made in which pore surface radiation was both modeled and neglected. The difference between yielding the integral contribution of radiative heat transfer mechanism to overall heat transport. Results indicate that radiative component of heat transfer within pores is small for conditions representative of light water reactor fuel, typically less than 1% of total heat transport. It is much larger, however, for conditions present in liquid metal fast breeder reactor fuel; during restructuring of this fuel type early in life, the radiative heat transfer mode was shown to contribute as much as 10-20% of total heat transport in hottest regions of fuel.

  19. Positive Transfer of Native Language in S econd Language Acquisition

    Institute of Scientific and Technical Information of China (English)

    王曼

    2014-01-01

    Language transfer can be divided into two types:positive transfer and negative transfer.Previous study always thinks that nega-tive transfer of native language should be taken seriously because it plays an important role in second language acquisition.However,as a matter of factor,positive transfer also has great influence on second language acquisition.This paper will give a detailed analysis of positive transfer from two aspects:syntactic transfer and phrase transfer.The paper also offers some methods in dealing with language transfer in second language acquisition.

  20. Emerging Trends of Research on Transfer of Learning

    Science.gov (United States)

    Subedi, Bhawani Shankar

    2004-01-01

    The terms "transfer of learning" and "transfer of training" are usually found mutually exclusive in training and development literature. Transfer is a key concept in adult learning theories because most education and training aspires to transfer. The end goals of training and education are not achieved unless transfer occurs. Emerging trends of…

  1. Transfer Area Mechanical Handling Calculation

    Energy Technology Data Exchange (ETDEWEB)

    B. Dianda

    2004-06-23

    This calculation is intended to support the License Application (LA) submittal of December 2004, in accordance with the directive given by DOE correspondence received on the 27th of January 2004 entitled: ''Authorization for Bechtel SAX Company L.L. C. to Include a Bare Fuel Handling Facility and Increased Aging Capacity in the License Application, Contract Number DE-AC28-01R W12101'' (Arthur, W.J., I11 2004). This correspondence was appended by further Correspondence received on the 19th of February 2004 entitled: ''Technical Direction to Bechtel SAIC Company L.L. C. for Surface Facility Improvements, Contract Number DE-AC28-OIRW12101; TDL No. 04-024'' (BSC 2004a). These documents give the authorization for a Fuel Handling Facility to be included in the baseline. The purpose of this calculation is to establish preliminary bounding equipment envelopes and weights for the Fuel Handling Facility (FHF) transfer areas equipment. This calculation provides preliminary information only to support development of facility layouts and preliminary load calculations. The limitations of this preliminary calculation lie within the assumptions of section 5 , as this calculation is part of an evolutionary design process. It is intended that this calculation is superseded as the design advances to reflect information necessary to support License Application. The design choices outlined within this calculation represent a demonstration of feasibility and may or may not be included in the completed design. This calculation provides preliminary weight, dimensional envelope, and equipment position in building for the purposes of defining interface variables. This calculation identifies and sizes major equipment and assemblies that dictate overall equipment dimensions and facility interfaces. Sizing of components is based on the selection of commercially available products, where applicable. This is not a specific recommendation for the future use

  2. Backward Charge Transfer in Conjugated Polymers

    Institute of Scientific and Technical Information of China (English)

    CHENG Meng-Xing; LI Guang-Qi; Thomas F. George; SUN Xin

    2005-01-01

    It has been known that the static polarizability of a polymer chain with a biexciton is negative. In order to understand this peculiar fact, this paper studies the dynamical process of the charge transfer in the polymer chain induced by an external electric field E during forming the biexciton. The time dependence of the charge distribution in the chain reveals that the charge transfer is backward: the positive charge shifts in the opposite direction of the external electric field. Such a backward charge transfer (BCT) produces an opposite dipole, which makes the polarization negative. The effect of electron interaction on the BCT is illustrated.

  3. Epigenetic reprogramming in mammalian nuclear transfer

    Institute of Scientific and Technical Information of China (English)

    LI Shijie; DU Weihua; LI Ning

    2004-01-01

    Somatic cloning has been succeeded in some species, but the cloning efficiency is very low, which limits the application of the technique in many areas of research and biotechnology. The cloning of mammals by somatic cell nuclear transfer (NT) requires epigenetic reprogramming of the differentiated state of donor cell to a totipotent, embryonic ground state. Accumulating evidence indicates that incomplete or inappropriate epigenetic reprogramming of donor nuclei is likely to be the primary cause of failures in nuclear transfer. This review summarizes the roles of various epigenetic mechanisms, including DNA methylation, histone acetylation, imprinting, X-chromosome inactivation, telomere maintenance and expressions of development-related genes on somatic nuclear transfer.

  4. Radiative Transfer in Special Relativity: Covariance

    CERN Document Server

    Duque, Mauricio; Duque, Carlos

    2007-01-01

    The purpose is to introduce in a clear and direct way the students of undergraduate courses in physics and/or astronomy to the subject of radiative transfer. A pedagogical revision is made in order to obtain the radiative transfer equation, its restrictions and the different types of interactions present between the radiation and the matter. Because in the classical literature about radiative transfer the covariance is not fully developed, we show in an explicit manner detail calculations and then we discuss the relativistic effects.

  5. Essentially Optimal Universally Composable Oblivious Transfer

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Nielsen, Jesper Buus; Orlandi, Claudio

    2009-01-01

    Oblivious transfer is one of the most important cryptographic primitives, both for theoretical and practical reasons and several protocols were proposed during the years. We provide the first oblivious transfer protocol which is simultaneously optimal on the following list of parameters: Security....... Communication complexity: it communicates O(1) group elements to transfer one out of two group elements. The Big-O notation hides 32, meaning that the communication is probably not optimal, but is essentially optimal in that the overhead is at least constant. Our construction is based on pairings, and we assume...

  6. Nerve Transfers to Restore Shoulder Function.

    Science.gov (United States)

    Leechavengvongs, Somsak; Malungpaishorpe, Kanchai; Uerpairojkit, Chairoj; Ng, Chye Yew; Witoonchart, Kiat

    2016-05-01

    The restoration of shoulder function after brachial plexus injury represents a significant challenge facing the peripheral nerve surgeons. This is owing to a combination of the complex biomechanics of the shoulder girdle, the multitude of muscles and nerves that could be potentially injured, and a limited number of donor options. In general, nerve transfer is favored over tendon transfer, because the biomechanics of the musculotendinous units are not altered. This article summarizes the surgical techniques and clinical results of nerve transfers for restoration of shoulder function. PMID:27094888

  7. Embryo Transfer (Techniques, Donors, and Recipients).

    Science.gov (United States)

    Phillips, Patrick E; Jahnke, Marianna M

    2016-07-01

    Commercial embryo transfer has evolved as an art and as a science since the early 1970s. Today's multiple ovulation embryo transfer is a widely used reproductive tool on many farms and is performed by veterinarians throughout the world. Propagation of the female genomes of select donors, through embryo transfer, has allowed a rapid progression of genetic gain in many breeds, much like what happened with artificial insemination since the 1940s. Advancement of this technology is migrating to in vitro fertilization technology today, allowing a higher volume of offspring to be produced with sex selection in the laboratory. PMID:27140299

  8. Environmental radon: solid earth-atmosphere transference

    International Nuclear Information System (INIS)

    The radon anomalies ant its descendants related with geophysical events are studied generally for to understand the involved mechanisms in the underground geochemistry. These anomalies were observed as a radioactivity level argumentation in the systems studied provoking a radioactivity transference from land toward human environment. In this work is presented an analysis of the contribution at local radioactivity level due to volcanic eruptions that they provoke a transference appreciable but intermittent and located of Radon to atmosphere and of that one due to soil-atmosphere transference that it occurs in continuous way in continent that it varies as function of meteorologic and geologic conditions. (Author)

  9. Translating Gene Transfer: A Stalled Effort

    OpenAIRE

    Greenberg, Alexandra J.; McCormick, Jennifer; Tapia, Carmen J.; Windebank, Anthony J.

    2011-01-01

    The journey of gene transfer from laboratory to clinic has been slow and fraught with many challenges and barriers. Despite the development of the initial technology in the early 1970s, a standard clinical treatment involving “gene therapy” remains to be seen. Furthermore, much was written about the technology in the early 1990s, but since then, not much has been written about the journey of gene transfer. The translational path of gene transfer thus far, both pitfalls and successes, can serv...

  10. Corporate Production Transfers to Developing Countries

    DEFF Research Database (Denmark)

    Bruun, Peter; Wulff, Henrik

    1997-01-01

    Production transfer is defined by the set of activities attached to send off, receipt and running-in a production system in a new environment. The activities concern handling of physical elements as well as non-material, knowledge based issues like documentation, education/training and management....... From a technical point of view this paper analyses some experiences of Danish companies' production transfers to the south-east Asia region with a focus on technology, quality, organisational and management issues as well as location concerns. Keywords: Production transfer, international production......, location, technology adaptation....

  11. Resonance energy transfer: Dye to metal nanoparticles

    International Nuclear Information System (INIS)

    In the present study, surface energy transfer (SET) from Coumarin 540A (C540 A) to Gold nanoparticle (Au) is demonstrated. The observed results show pronounced effect on the photoluminescence intensity and shortening of the lifetime of Coumarin 540A upon interaction with the spherical gold nanoparticle, also there are measured effects on radiative rate of the dye. Experimental results are analyzed with fluorescence resonance energy transfer (FRET) and SET theories. The results obtained from distance-dependent quenching provide experimental evidence that the efficiency curve slope and distance of quenching is best modeled by surface energy transfer process

  12. Resonance energy transfer: Dye to metal nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Wari, M. N.; Pujar, G. H.; Inamdar, S. R., E-mail: him-lax3@yahoo.com [Laser Spectroscopy Programme, Department of Physics, Karnatak University, Dharwad-580003 (India)

    2015-06-24

    In the present study, surface energy transfer (SET) from Coumarin 540A (C540 A) to Gold nanoparticle (Au) is demonstrated. The observed results show pronounced effect on the photoluminescence intensity and shortening of the lifetime of Coumarin 540A upon interaction with the spherical gold nanoparticle, also there are measured effects on radiative rate of the dye. Experimental results are analyzed with fluorescence resonance energy transfer (FRET) and SET theories. The results obtained from distance-dependent quenching provide experimental evidence that the efficiency curve slope and distance of quenching is best modeled by surface energy transfer process.

  13. Transfer induced compressive strain in graphene

    DEFF Research Database (Denmark)

    Larsen, Martin Benjamin Barbour Spanget; Mackenzie, David; Caridad, Jose;

    2014-01-01

    We have used spatially resolved micro Raman spectroscopy to map the full width at half maximum (FWHM) of the graphene G-band and the 2D and G peak positions, for as-grown graphene on copper catalyst layers, for transferred CVD graphene and for micromechanically exfoliated graphene, in order...... to characterize the effects of a transfer process on graphene properties. Here we use the FWHM(G) as an indicator of the doping level of graphene, and the ratio of the shifts in the 2D and G bands as an indicator of strain. We find that the transfer process introduces an isotropic, spatially uniform, compressive...

  14. Coordinating knowledge transfer within manufacturing networks

    DEFF Research Database (Denmark)

    Yang, Cheng; Johansen, John; Boer, Harry

    2008-01-01

    Along with increasing globalization, the management of international manufacturing networks is becoming increasingly important for industrial companies. This paper mainly focuses on the coordination of knowledge transfer within manufacturing networks. In this context, we propose the time......-place matrix as a tool for mapping the distribution of knowledge within manufacturing networks. Using this tool, four important questions about the coordination of knowledge transfer within a manufacturing network are identified: know-where, know-what, know-when, know-how to transfer. The relationships among...... these questions are discussed, based on which a frame of thought is proposed that managers can use in their quest for network competitiveness....

  15. Electron acceleration during the decay of nonlinear Whistler waves in low-beta electron-ion plasma

    Energy Technology Data Exchange (ETDEWEB)

    Umeda, Takayuki; Saito, Shinji [Solar-Terrestrial Environment Laboratory, Nagoya University, Nagoya City, Aichi 464-8601 (Japan); Nariyuki, Yasuhiro, E-mail: umeda@stelab.nagoya-u.ac.jp, E-mail: saito@stelab.nagoya-u.ac.jp, E-mail: nariyuki@edu.u-toyama.ac.jp [Faculty of Human Development, University of Toyama, Toyama City, Toyama 930-8555 (Japan)

    2014-10-10

    Relativistic electron acceleration through dissipation of a nonlinear, short-wavelength, and monochromatic electromagnetic whistler wave in low-beta plasma is investigated by utilizing a one-dimensional fully relativistic electromagnetic particle-in-cell code. The nonlinear (large-amplitude) parent whistler wave decays through the parametric instability which enhances electrostatic ion acoustic waves and electromagnetic whistler waves. These waves satisfy the condition of three-wave coupling. Through the decay instability, the energy of electron bulk velocity supporting the parent wave is converted to the thermal energy perpendicular to the background magnetic field. Increase of the perpendicular temperature triggers the electron temperature anisotropy instability which generates broadband whistler waves and heats electrons in the parallel direction. The broadband whistler waves are inverse-cascaded during the relaxation of the electron temperature anisotropy. In lower-beta conditions, electrons with a pitch angle of about 90° are successively accelerated by inverse-cascaded whistler waves, and selected electrons are accelerated to over a Lorentz factor of 10. The result implies that the nonlinear dissipation of a finite-amplitude and short-wavelength whistler wave plays an important role in producing relativistic nonthermal electrons over a few MeV especially at lower beta plasmas.

  16. Results from a 64-pixel PIN-diode detector system for low-energy beta-electrons

    Energy Technology Data Exchange (ETDEWEB)

    Wuestling, Sascha, E-mail: sascha.wuestling@kit.ed [Forschungszentrum Karlsruhe, Institut fuer Prozessdatenverarbeitung und Elektronik, Postfach 3640, 76021 Karlsruhe (Germany); Fraenkle, F.; Habermehl, F.; Renschler, P. [Universitaet Karlsruhe - TH, Institut fuer Experimentelle Kernphysik, Postfach 6980, 76128 Karlsruhe (Germany); Steidl, M [Forschungszentrum Karlsruhe, Institut fuer Kernphysik, Postfach 3640, 76021 Karlsruhe (Germany)

    2010-12-11

    The KATRIN neutrino mass experiment is based on a precise energy measurement ({Delta}E/E=5x10{sup -5}) of electrons emerging from tritium beta decay (E{sub max}=18.6 keV). This is done by a large electrostatic retarding spectrometer (MAC-E Filter), which is followed by an electron detector. Key requirements for this detector are a large sensitive area ({approx}80 cm{sup 2}), a certain energy resolution ({Delta}E=600 eV - 18.6 keV) but also a certain spatial resolution ({approx}3 mm), which leads to a multi-pixel design. As a tentative design on the way to the final detector, but also for operational service on the so-called pre-spectrometer experiment, a detector system with a reduced size (16 cm{sup 2}) and a reduced pixel number (64), making use of a monolithic segmented silicon PIN diode, was designed and built. While the design and very first measurements have been presented in Wuestling et al. , this publication shows the operational performance of the detector system. The robust concept of the electronics allowed adaptation to mechanically different experimental setups. The spacial resolution of the detector system proved to be essential in examining Penning trap induced background and other effects in the pre-spectrometer experiment. The detector performance test runs include energy resolution and calibration, background rates, correlation between pixels (crosstalk), spatially resolved rate analysis, and a dead-layer measurement . The detector allows for background searches with a sensitivity as low as 1.3x10{sup -3} cps/cm{sup 2} in the energy range of 20 keV. This allows the pre-spectrometer to be characterized with e-gun illumination with a signal to background ratio of better than 10{sup 5} and the search for ultra low Penning discharge emissions.

  17. Dimensions of Motivation to Transfer: A Longitudinal Analysis of Their Influence on Retention, Transfer, and Attitude Change

    Science.gov (United States)

    Gegenfurtner, Andreas

    2013-01-01

    This longitudinal study examined the multidimensionality of motivation to transfer training. Based on self-determination theory, expectancy theory, and the theory of planned behaviour, motivation to transfer was conceptualized in three dimensions: autonomous motivation to transfer, controlled motivation to transfer, and intention to transfer.…

  18. BioShuttle-mediated Plasmid Transfer

    Directory of Open Access Journals (Sweden)

    Klaus Braun, Leonie von Brasch, Ruediger Pipkorn, Volker Ehemann, Juergen Jenne, Herbert Spring, Juergen Debus, Bernd Didinger, Werner Rittgen, Waldemar Waldeck

    2007-01-01

    Full Text Available An efficient gene transfer into target tissues and cells is needed for safe and effective treatment of genetic diseases like cancer. In this paper, we describe the development of a transport system and show its ability for transporting plasmids. This non-viral peptide-based BioShuttle-mediated transfer system consists of a nuclear localization address sequence realizing the delivery of the plasmid phNIS-IRES-EGFP coding for two independent reporter genes into nuclei of HeLa cells. The quantification of the transfer efficiency was achieved by measurements of the sodium iodide symporter activity. EGFP gene expression was measured with Confocal Laser Scanning Microscopy and quantified with biostatistical methods by analysis of the frequency of the amplitude distribution in the CLSM images. The results demonstrate that the “BioShuttle”-Technology is an appropriate tool for an effective transfer of genetic material carried by a plasmid.

  19. Oxygen transfer in human carotid artery bifurcation

    Institute of Scientific and Technical Information of China (English)

    Z.G.Zhang; Y.B.Fan; X.Y.Deng

    2007-01-01

    Arterial bifurcations are places where blood flow may be disturbed and slow recirculation flow may occur.To reveal the correlation between local oxygen transfer and atherogenesis, a finite element method was employed to simulate the blood flow and the oxygen transfer in the human carotid artery bifurcation. Under steady-state flow conditions, the numerical simulation demonstrated a variation in local oxygen transfer at the bifurcation, showing that the convective condition in the disturbed flow region may produce uneven local oxygen transfer at the blood/wall interface.The disturbed blood flow with formation of slow eddies in the carotid sinus resulted in a depression in oxygen supply to the arterial wall at the entry of the sinus, which in turn may lead to an atherogenic response of the arterial wall, and contribute to the development of atherosclerotic stenosis there.

  20. Lower Bounds for Quantum Oblivious Transfer

    CERN Document Server

    Chailloux, André; Sikora, Jamie

    2010-01-01

    Oblivious transfer is a fundamental primitive in cryptography. While perfect information theoretic security is impossible, quantum oblivious transfer protocols can limit the dishonest players' cheating. Finding the optimal security parameters in such protocols is an important open question. In this paper we show that every 1-out-of-2 oblivious transfer protocol allows a dishonest party to cheat with probability bounded below by a constant strictly larger than 1/2. Alice's cheating is defined as her probability of guessing Bob's index, and Bob's cheating is defined as his probability of guessing both input bits of Alice. In our proof, we relate these cheating probabilities to the cheating probabilities of a coin flipping protocol and conclude by using Kitaev's coin flipping lower bound. Then, we present an oblivious transfer protocol with two messages and cheating probabilities at most 3/4. Last, we extend Kitaev's semidefinite programming formulation to more general primitives, where the security is against a...

  1. Exclusive processes at high momentum transfer

    CERN Document Server

    Radyushkin, Anatoly; Stoker, Paul

    2002-01-01

    This book focuses on the physics of exclusive processes at high momentum transfer and their description in terms of generalized parton distributions, perturbative QCD, and relativistic quark models. It covers recent developments in the field, both theoretical and experimental.

  2. Transfer to hospital in planned home births

    DEFF Research Database (Denmark)

    Blix, Ellen; Kumle, Merethe; Kjærgaard, Hanne;

    2014-01-01

    BACKGROUND: There is concern about the safety of homebirths, especially in women transferred to hospital during or after labour. The scope of transfer in planned home births has not been assessed in a systematic review. This review aimed to describe the proportions and indications for transfer from...... home to hospital during or after labour in planned home births. METHODS: The databases Pubmed, Embase, Cinahl, Svemed+, and the Cochrane Library were searched using the MeSH term "home childbirth". Inclusion criteria were as follows: the study population was women who chose planned home birth...... at the onset of labour; the studies were from Western countries; the birth attendant was an authorised midwife or medical doctor; the studies were published in 1985 or later, with data not older than from 1980; and data on transfer from home to hospital were described. Of the 3366 titles identified, 83 full...

  3. Radionuclide transfer from contaminated field to crops

    International Nuclear Information System (INIS)

    Since the policy for land disposal of radioactive wastes were proposed, the importance of terrestrial radioecology has been re-recognized in Japan. The National Institute of Radiological Sciences (NIRS) held a Two-Day Seminar concerning terrestrial transfer of radionuclides. This is a compilation of papers presented at the seminar. The purpose of the seminar is twofold: firstly, to raise basic problems concerning transfer of not only radionuclides but also elements into crops, as well as to present NIRS's studies on radionuclide transfer; and secondly, to discuss in depth the topics about possible transfer of I-129 into rice plant arising from the commercial fuel reprocessing plant, the construction of which is under planning. Finally, general discussion of further issues on radioecology is given. (Namekawa, K.)

  4. 7 CFR 3565.504 - Transfers.

    Science.gov (United States)

    2010-01-01

    ... GUARANTEED RURAL RENTAL HOUSING PROGRAM Agency Guaranteed Loans That Back Ginnie Mae Guaranteed Securities § 3565.504 Transfers. (a) Loans and/or mortgage servicing on loans backing Ginnie Mae...

  5. Polarization transfer in relativistic magnetized plasmas

    CERN Document Server

    Heyvaerts, Jean; Prunet, Simon; Thiebaut, Jerome

    2012-01-01

    The polarization transfer coefficients of a relativistic magnetized plasma are derived. These results apply to any momentum distribution function of the particles, isotropic or anisotropic. Particles interact with the radiation either in a non resonant mode when the frequency of the radiation exceeds their characteristic synchrotron emission frequency, or quasi resonantly otherwise. These two classes of particles contribute differently to the polarization transfer coefficients. For a given frequency, this dichotomy corresponds to a regime change in the dependence of the transfer coefficients on the parameters of the particle s population. The derivation of the transfer coefficients involves an exact expression of the conductivity tensor of the relativistic magnetized plasma that has not been used hitherto in this context. Suitable expansions valid at frequencies larger than the cyclotron frequency allow us to analytically perform the summation over all resonances at high harmonics of the relativistic gyrofreq...

  6. Technology transfers, foreign investment and productivity spillovers

    DEFF Research Database (Denmark)

    Newman, Carol; Rand, John; Talbot, Theodore Purdendu;

    2015-01-01

    transfers of knowledge/technology between linked firms) from productivity effects through indirect FDI spillovers. In addition to identifying indirect vertical productivity spillovers from FDI, our results show that there are productivity gains associated with direct linkages between foreign...

  7. Earth--Mars Transfers with Ballistic Capture

    CERN Document Server

    Topputo, Francesco

    2014-01-01

    We construct a new type of transfer from the Earth to Mars, which ends in ballistic capture. This results in a substantial savings in capture $\\Delta v$ from that of a classical Hohmann transfer under certain conditions. This is accomplished by first becoming captured at Mars, very distant from the planet, and then from there, following a ballistic capture transfer to a desired altitude within a ballistic capture set. This is achieved by manipulating the stable sets, or sets of initial conditions whose orbits satisfy a simple definition of stability. This transfer type may be of interest for Mars missions because of lower capture $\\Delta v$, moderate flight time, and flexibility of launch period from the Earth.

  8. Repatriates as Knowlege-transfer Agents

    DEFF Research Database (Denmark)

    Lemmergaard, Jeanette; Sanchez Vidal, Ma Eugenia

    Expatriates are increasingly recognized for their central role as knowledge-transfer agents. Traditionally expatriates were only sent out to control and coordinate activities, but in the knowledge economy international assignments are seen as a way of obtaining knowledge-transfer between...... organizational units. Or put differently, international assignments initiate knowledge management.   Most of the knowledge acquired during a foreign assignment is however tacit and therefore difficult to codify and transfer in a systematic way. Moreover, research shows that many repatriates leave their employer......,how the absorptive capacity of organizations restricts the organizations from seeing the value of the knowledge of the expatriates. Second, the disseminative capacity of the organizations. Finally, the paper discusses how channels of knowledge transfer can support knowledge resourcing to the benefit of both...

  9. Join TTC! | NCI Technology Transfer Center | TTC

    Science.gov (United States)

    The NCI Technology Transfer Center (TTC) offers a unique opportunity for training through the NCI TTC Fellowship program. TTC also has a unit dedicated to marketing these research opportunities and their underlying technologies to potential collaborators and licensees.

  10. Transfer color to night vision images

    Institute of Scientific and Technical Information of China (English)

    Shaoyuan Sun; Zhongliang Jing; Gang Liu; Zhenhua Li

    2005-01-01

    @@ Natural color appearance is the key problem of color night vision field. In this paper, the color mood of daytime color image is transferred to the monochromic night vision image. This method gives the night image a natural color appearance. For each pixel in the night vision image, the best matching pixel in the color image is found based on texture similarity measure. Entropy, energy, contrast, homogeneity, and correlation features based on co-occurrence matrix are combined as texture similarity measure to find the corresponding pixels between the two images. We use a genetic algorithm (GA) to find the optimistic weighting factors assigned to the five different features. GA is also employed in searching the matching pixels to make the color transfer algorithm faster. When the best matching pixel in the color image is found, the chromaticity values are transferred to the corresponding pixel of the night vision image. The experiment results demonstrate the efficiency of this natural color transfer technique.

  11. Allowance Holdings and Transfers Data Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Allowance Holdings and Transfers Data Inventory contains measured data on holdings and transactions of allowances under the NOx Budget Trading Program (NBP), a...

  12. BioShuttle-mediated Plasmid Transfer

    Science.gov (United States)

    Braun, Klaus; von Brasch, Leonie; Pipkorn, Ruediger; Ehemann, Volker; Jenne, Juergen; Spring, Herbert; Debus, Juergen; Didinger, Bernd; Rittgen, Werner; Waldeck, Waldemar

    2007-01-01

    An efficient gene transfer into target tissues and cells is needed for safe and effective treatment of genetic diseases like cancer. In this paper, we describe the development of a transport system and show its ability for transporting plasmids. This non-viral peptide-based BioShuttle-mediated transfer system consists of a nuclear localization address sequence realizing the delivery of the plasmid phNIS-IRES-EGFP coding for two independent reporter genes into nuclei of HeLa cells. The quantification of the transfer efficiency was achieved by measurements of the sodium iodide symporter activity. EGFP gene expression was measured with Confocal Laser Scanning Microscopy and quantified with biostatistical methods by analysis of the frequency of the amplitude distribution in the CLSM images. The results demonstrate that the “BioShuttle”-Technology is an appropriate tool for an effective transfer of genetic material carried by a plasmid. PMID:18026568

  13. Methods and theories on transfer prices

    Directory of Open Access Journals (Sweden)

    M. Boiţă

    2013-06-01

    Full Text Available In the current global economic situation, when multinationals companies are no longer a rarity and the increase of volume and frequency of intra-group transactions are a reality, the transfer prices issue has become a problem for big companies because it significantly affects the fiscal task of the groups. The transfer price is basically the price used for transfer of tangible and intangible assets between related parties and it should be determined on the basis of market value without being influenced by the relationship of affiliation. However, if for services or tangible assets, the comparison of the transfer price to the market one is relatively easy to achieve, for the intangible ones, quantifying future benefits waived by the affiliated person compared to the situation in which it would be independent is harder to be established.

  14. China’s Transfer Pricing Measures

    Institute of Scientific and Technical Information of China (English)

    RICHARD; HOFFMANN

    2009-01-01

    Earlier this year, the State Administrationof Taxation promulgated the much-antic-ipated transfer pricing measures detailingthe administrative rules for all special taxadjustments. These special tax adjustments,including cost sharing, thin capitalization,

  15. Transfer and Cohesion in Interdisciplinary Education

    Directory of Open Access Journals (Sweden)

    Søren Harnow Klausen

    2014-06-01

    Full Text Available One of the great challenges of interdisciplinary education is to create sufficient cohesion between disciplines. It is suggested that cohesion depends on the transfer of knowledge (in a broad sense, which includes skill and competences among the disciplines involved. Some of the most characteristic types of such transfer are identified and analyzed: Transfer of factual knowledge, theories, methods, models, skills, modes of collaboration and organization, meta-competences, disciplinary self-consciousness, problem selection, framework construction and motivation. Though some of these types of transfer may have a greater or smaller potential for creating cohesion, different kinds of cohesion may serve different interests, and there is no reason to assume that e.g. joint problem solving or theoretical integration should be more conducive to cohesion than e.g. contributions to motivation or disciplinary self-consciousness.

  16. ATLAS Canada lightpath data transfer trial

    CERN Document Server

    Kost, C J; Caron, B; Hong, W

    2003-01-01

    Emerging grids play a significant role in the computational, data, storage, and network requirements of high energy physics experiments coming online in the next few years. One such requirement, the bulk transfer of data over advanced high speed optical networks is necessary as such experiments are highly distributed with resources and participants from research laboratories and institutions spanning the globe. This trial at the iGrid 2002 conference attempts to stress the feasibility of high speed bulk data transfer over an end-to-end lightpath, a dedicated point-to-point optical link. Specifically, the objective was to transfer 1 TB of Monte Carlo data from TRIUMF in Vancouver, Canada, to CERN in Geneva, Switzerland. A rate equivalent to transferring a full CD of data every 8 s was achieved. (15 refs).

  17. Generalized parton distributions at large momentum transfer

    OpenAIRE

    Kroll, P.

    2001-01-01

    The role of generalized parton distributions in wide-angle exclusive reactions will be discussed. In contrast to deep virtual exclusive reactions the wide angle processes offer the possibility of investigating the generalized parton distributions at large momentum transfer.

  18. Saturn facility oil transfer automation system

    Energy Technology Data Exchange (ETDEWEB)

    Joseph, Nathan R.; Thomas, Rayburn Dean; Lewis, Barbara Ann; Malagon, Hector Ricardo.

    2014-02-01

    The Saturn accelerator, owned by Sandia National Laboratories, has been in operation since the early 1980s and still has many of the original systems. A critical legacy system is the oil transfer system which transfers 250,000 gallons of transformer oil from outside storage tanks to the Saturn facility. The oil transfer system was iden- ti ed for upgrade to current technology standards. Using the existing valves, pumps, and relay controls, the system was automated using the National Instruments cRIO FGPA platform. Engineered safety practices, including a failure mode e ects analysis, were used to develop error handling requirements. The uniqueness of the Saturn Oil Automated Transfer System (SOATS) is in the graphical user interface. The SOATS uses an HTML interface to communicate to the cRIO, creating a platform independent control system. The SOATS was commissioned in April 2013.

  19. Environment assisted energy transfer in dimer system

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Salman, E-mail: sksafi@comsats.edu.pk [Department of Physics, COMSATS Institute of Information Technology, Chak Shahzad, Islamabad (Pakistan); Ibrahim, M.; Khan, M.K. [Department of Physics, Quaid-i-Azam University, Islamabad (Pakistan)

    2014-02-15

    The influence of collective and multilocal environments on the energy transfer between the levels of a dimer is studied. The dynamics of energy transfer are investigated by considering coupling of collective environment with the levels of the dimer in the presence of both two individuals and mutually correlated multilocal environments. It is shown that every way of coupling we consider assists, though differently, the probability of transition between the levels of dimer. The probability of transition is strongly enhanced when the two local environments are mutually correlated. -- Highlights: • The dynamics of energy transfer between the levels of a dimer are studied. • Coupling of collective as well as individual environments are considered. • The environments are in spin star configurations. • The environment assists the energy transfer between the levels. • For correlated multilocal environments, the transition probability is almost 100%.

  20. Knowledge transfer in family business successions

    DEFF Research Database (Denmark)

    Boyd, Britta; Royer, Susanne; Pei, Rong;

    2015-01-01

    cultures is investigated in this paper. From a resource-oriented and transaction cost inspired perspective two family businesses with a similar industry background from China and Europe are compared regarding knowledge transfer in the context of family firm succession taking into account the respective......Purpose – Knowledge often is the fundament for strategic competitive advantage. Thus, it is highly relevant to understand better how knowledge is transferred from one generation to the next in family businesses. The purpose of this paper is to link the competitive advantage realisation in family...... businesses to the success of transferring strategically valuable knowledge in different business environments to the next generation. Design/methodology/approach – Building on the contingency model of family business succession (Royer et al., 2008) knowledge transfer in family businesses from different...

  1. When Do Market Games Have Transferable Utility?

    OpenAIRE

    Bergstrom, Ted; Varian, Hal

    1985-01-01

    A question with a nice clean answer. When do market games have transferable utility? Subject to some regularity conditions, the answer is if and only if indirect utility can be represented in the Gorman polar form.

  2. [Technology transfer of building materials by ECOMAT

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    This report discusses the plan for technology transfer of building materials developed by ECOMAT to the commercial private sector. Some of the materials are briefly discussed like foams, fiber reinforcement, fly ash development, and polymer fillers.

  3. Endwall convective heat transfer for bluff bodies

    DEFF Research Database (Denmark)

    Wang, Lei; Salewski, Mirko; Sundén, Bengt;

    2012-01-01

    The endwall heat transfer characteristics of forced flow past bluff bodies have been investigated using liquid crystal thermography (LCT). The bluff body is placed in a rectangular channel with both its ends attached to the endwalls. The Reynolds number varies from 50,000 to 100,000. In this study......, a single bluff body and two bluff bodies arranged in tandem are considered. Due to the formation of horseshoe vortices, the heat transfer is enhanced appreciably for both cases. However, for the case of two bluff bodies in tandem, it is found that the presence of the second bluff body decreases the heat...... transfer as compared to the case of a single bluff body. In addition, the results show that the heat transfer exhibits Reynolds number similarity. For a single bluff body, the Nusselt number profiles collapse well when the data are scaled by Re0.55; for two bluff bodies arranged in tandem, the heat...

  4. The Application of Rewriting in Cultural Transfer

    Institute of Scientific and Technical Information of China (English)

    赵敏洁

    2016-01-01

    In the context of globalization, cultural exchange is frequently conducted between countries in translating activities. Comparing with linguistic transfer, cultural transfer is frequented applied as to achieve communicative equivalence. Studies of rewriting applied as a method of cultural translation from Chinese to English are still relatively weak in the field of translation in China. Exclusive research on the methods for cultural translation is still uncompleted. In the last decade, when comes to cultural elements in translation, methods as restoring sounds, adding extra explanation, or detecting equivalent concepts have been most-ly discussed, but rewriting is rarely involved in it. This thesis reviews previous definitions for rewriting or adaptation;analyses the difference between linguistic transfer and cultural transfer, and why rewriting is adopted as an effective method for cultural translation;the application of rewriting will break up the dominance of occidental culture in the world while make oriental cul-ture become influential in the western world.

  5. On Thermodynamic Interpretation of Transfer Entropy

    Directory of Open Access Journals (Sweden)

    Don C. Price

    2013-02-01

    Full Text Available We propose a thermodynamic interpretation of transfer entropy near equilibrium, using a specialised Boltzmann’s principle. The approach relates conditional probabilities to the probabilities of the corresponding state transitions. This in turn characterises transfer entropy as a difference of two entropy rates: the rate for a resultant transition and another rate for a possibly irreversible transition within the system affected by an additional source. We then show that this difference, the local transfer entropy, is proportional to the external entropy production, possibly due to irreversibility. Near equilibrium, transfer entropy is also interpreted as the difference in equilibrium stabilities with respect to two scenarios: a default case and the case with an additional source. Finally, we demonstrated that such a thermodynamic treatment is not applicable to information flow, a measure of causal effect.

  6. Soluble pig for radioactive waste transfer lines

    International Nuclear Information System (INIS)

    Flushing transfer pipe after radioactive waste transfers generates thousands of gallons of additional radioactive waste each year at the Hanford site. The use of pneumatic pigging with waste soluble pigs as a means to clear transfer piping may be an effective alternative to raw water flushes. A feasibility study was performed by a group of senior mechanical engineering students for their senior design project as part of their curriculum at Washington State University. The students divided the feasibility study into three sub-projects involving: (1) material research, (2) delivery system design, and (3) mockup fabrication and testing. The students screened through twenty-three candidate materials and selected a thermoplastic polymer combined 50:50 wt% with sucrose to meet the established material performance criteria. The students also prepared a conceptual design of a remote pneumatic delivery system and constructed a mockup section of transfer pipe for testing the prototype pigs

  7. Stochastic Radiative transfer and real cloudiness

    Energy Technology Data Exchange (ETDEWEB)

    Evans, F. [Univ. of Colorado, Boulder, CO (United States)

    1995-09-01

    Plane-parallel radiative transfer modeling of clouds in GCMs is thought to be an inadequate representation of the effects of real cloudiness. A promising new approach for studying the effects of cloud horizontal inhomogeneity is stochastic radiative transfer, which computes the radiative effects of ensembles of cloud structures described by probability distributions. This approach is appropriate because cloud information is inherently statistical, and it is the mean radiative effect of complex 3D cloud structure that is desired. 2 refs., 1 fig.

  8. Transfer learning approach for financial applications

    OpenAIRE

    Stamate, Cosmin; Magoulas, George D.; Thomas, Michael S.C.

    2015-01-01

    Artificial neural networks learn how to solve new problems through a computationally intense and time consuming process. One way to reduce the amount of time required is to inject preexisting knowledge into the network. To make use of past knowledge, we can take advantage of techniques that transfer the knowledge learned from one task, and reuse it on another (sometimes unrelated) task. In this paper we propose a novel selective breeding technique that extends the transfer learning with behav...

  9. Nanoscale Heat Transfer: from Computation to Experiment

    OpenAIRE

    Luo, Tengfei; Chen, Gang

    2013-01-01

    Heat transfer can differ distinctly at the nanoscale from that at the macroscale. Recent advancement in computational and experimental techniques has enabled a large number of interesting observations and understanding of heat transfer processes at the nanoscale. In this review, we will first discuss recent advances in computational and experimental methods used in nanoscale thermal transport studies, followed by reviews of novel thermal transport phenomena at the nanoscale observed in both c...

  10. Nanoscale heat transfer - from computation to experiment

    OpenAIRE

    Luo, Tengfei; Chen, Gang

    2012-01-01

    Heat transfer can differ distinctly at the nanoscale from that at the macroscale. Recent advancement in computational and 5 experimental techniques has enabled a large number of interesting observations and understanding of heat transfer processes at the nanoscale. In this review, we will first discuss recent advances in computational and experimental methods used in nanoscale thermal transport studies, followed by reviews of novel thermal transport phenomena at the nanoscale obse...

  11. Development of a conjugate heat transfer solver

    OpenAIRE

    Al-Qubeissi, Mansour

    2013-01-01

    The current research study presents a numerical approach in modelling the conjugate heat transfer system of the gas-turbine rotating discs-cavities. The work was undertaken to understand such phenomena and, more specifically, to numerically investigate the thermal interactions in rotating discs-cavities. The developed solver is capable of dealing with complex heat transfer problems, such as unsteady three-dimensional compressible rotating-flows. The development was based on integrating...

  12. The Transfer of Property Rights by Theft

    DEFF Research Database (Denmark)

    Rose, Caspar

    2005-01-01

    This article studies the involuntary transfer of property rights by theft - a topic almostunexplored in the law and economics literature. The question is whether a buyer of a stolen goodshould obtain title to the good if he/she has purchased it in good faith. As described in the articledifferent...... the ownership when good faith is decisive for the transfer of property rights.JEL Classification: K11, K14 and K42Keywords: property right law, theft, good faith and game theory...

  13. The Simplest Protocol for Oblivious Transfer

    DEFF Research Database (Denmark)

    Chou, Tung; Orlandi, Claudio

    2015-01-01

    Oblivious Transfer (OT) is the fundamental building block of cryptographic protocols. In this paper we describe the simplest and most efficient protocol for 1-out-of-n OT to date, which is obtained by tweaking the Diffie-Hellman key-exchange protocol. The protocol achieves UC-security against...... optimizations) is at least one order of magnitude faster than previous work. Category / Keywords: cryptographic protocols / Oblivious Transfer, UC Security, Elliptic Curves, Efficient Implementation...

  14. Technology transfer pilot study. Final report

    International Nuclear Information System (INIS)

    Four specific technologies based on the Initial Fusion Program were targeted for this initial study. The areas chosen were the CO2 laser, high pressure from cleaning, video multiplexer, and plans-optics polishing. The study concluded that both Government and Industry are willing and anxious to promote and to reap the benefits of technology transfer. Recommendations were made in the areas of patent policy, documentation procedures in the transfer process, awareness training, and expansion of the scope of the study. 18 refs

  15. Mass transfer coefficients in metallurgical reactors

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    An overview on the application and achievements of physico-mathematical modeling of metallurgical processes in Chinais briefly declared. The important role of coefficients in model formulation is shown from our experience. The mass transfer coeffi-cients of the slag-metal reactions and the gas-metal reactions are discussed referring to the flow conditions near the interface. Theinfluence of the surface-active species on the mass transfer and the inteffacial reaction is also discussed briefly.

  16. HRM Practices and MNC knowledge Transfer

    DEFF Research Database (Denmark)

    Minbaeva, Dana

    2004-01-01

    The purpose of the paper is to determine and empirically examine the effect of human resourcemanagement practices on knowledge transfer within multinational corporations. It is suggested thatthe employment of human resource practices, which affect absorptive capacity of knowledgereceivers...... from these arguments are tested on the data from 92subsidiaries of Danish multinational corporations located in 11 countries.Key words: knowledge transfer, multintional corporations, HRM, complementarity...

  17. HRM Practices and MNC Knowledge Transfer

    DEFF Research Database (Denmark)

    Minbaeva, Dana

    2003-01-01

    ABSTRACTThe paper supports the idea that organizations can institute various internal structures,policies and practices to overcome transfer barriers and facilitate the degree of knowledgetransfer. I discuss a framework for future empirical research on the relations betweenhuman resource management...... (HRM) practices and knowledge transfer in multinationalcorporations (MNC). The proposed model is empirically testable, includes a wider rangeof HRM practices and is not limited to one mode of foreign operations only....

  18. Intergenerational Transfers, Lifetime Welfare and Resource Preservation

    OpenAIRE

    Valente, Simone

    2006-01-01

    This paper analyzes overlapping-generations models where natural capital is owned by selfish agents. Transfers in favor of young agents reduce the rate of depletion and increase output growth. It is shown that intergenerational transfers may be preferred to laissez-faire by an indefinite sequence of generations: if the resource share in production is sufficiently high, the welfare gain induced by preser- vation compensates for the loss due to taxation. This conclusion is reinforced when other...

  19. Ozone mass transfer and kinetics experiments

    Energy Technology Data Exchange (ETDEWEB)

    Bollyky, L.J.; Beary, M.M.

    1981-12-01

    Experiments were conducted at the Hanford Site to determine the most efficient pH and temperature levels for the destruction of complexants in Hanford high-level defense waste. These complexants enhance migration of radionuclides in the soil and inhibit the growth of crystals in the evaporator-crystallizer. Ozone mass transfer and kinetics tests have been outlined for the determination of critical mass transfer and kinetics parameters of the ozone-complexant reaction.

  20. Ozone mass transfer and kinetics experiments

    International Nuclear Information System (INIS)

    Experiments were conducted at the Hanford Site to determine the most efficient pH and temperature levels for the destruction of complexants in Hanford high-level defense waste. These complexants enhance migration of radionuclides in the soil and inhibit the growth of crystals in the evaporator-crystallizer. Ozone mass transfer and kinetics tests have been outlined for the determination of critical mass transfer and kinetics parameters of the ozone-complexant reaction

  1. Mass Transfer Operations for the Practicing Engineer

    CERN Document Server

    Theodore, Louis

    2011-01-01

    Part of the Essential Engineering Calculations Series, this book presents step-by-step solutions of the basic principles of mass transfer operations, including sample problems and solutions and their applications, such as distillation, absorption, and stripping. Presenting the subject from a strictly pragmatic point of view, providing both the principles of mass transfer operations and their applications, with clear instructions on how to carry out the basic calculations needed, the book also covers topics useful for readers taking their professional exams.

  2. Methods for calculating anisotropic transfer cross sections

    International Nuclear Information System (INIS)

    The Legendre moments of the group transfer cross section, which are widely used in the numerical solution of the transport calculation can be efficiently and accurately constructed from low-order (K = 1--2) successive partial range moments. This is convenient for the generation of group constants. In addition, a technique to obtain group-angle correlation transfer cross section without Legendre expansion is presented. (author)

  3. HRM practices and knowledge transfer in MNCS

    OpenAIRE

    Minbaeva, Dana B.

    2007-01-01

    This chapter introduces HRM practices that help MNCs to overcome knowledge transfer barriers (knowledge-driven HRM practices). It argues that MNCs can institute various HRM practices that impact knowledge transfer barriers associated with behavior of knowledge senders and receivers. HRM practices relevant for absorptive capacity of subsidiary employees form two groups – cognitive (job analysis, recruitment, selection, international rotation, career management, training and performance appr...

  4. Analysis on Language Transfer And English Learning

    Institute of Scientific and Technical Information of China (English)

    龙宗莉

    2013-01-01

    Language is an important part of culture. With the development of global economy and the integration of the world,English is playing a more and more important role in communication. But for Chinese students,negative language transfer is a big obstacle that they must overcome if they want to master this language. In this paper,I will mainly analyze causes and different kinds of negative transfer in English learning.

  5. Targeting Radiotherapy to Cancer by Gene Transfer

    OpenAIRE

    R. J. Mairs; Boyd, M.

    2003-01-01

    Targeted radionuclide therapy is an alternative method of radiation treatment which uses a tumor-seeking agent carrying a radioactive atom to deposits of tumor, wherever in the body they may be located. Recent experimental data signifies promise for the amalgamation of gene transfer with radionuclide targeting. This review encompasses aspects of the integration of gene manipulation and targeted radiotherapy, highlighting the possibilities of gene transfer to assist the targeting of cancer ...

  6. Inpatient Transfers to the Intensive Care Unit

    Science.gov (United States)

    Young, Michael P; Gooder, Valerie J; McBride, Karen; James, Brent; Fisher, Elliott S

    2003-01-01

    OBJECTIVE To examine if delayed transfer to the intensive care unit (ICU) after physiologic deterioration is associated with increased morbidity and mortality. DESIGN Inception cohort. SETTING Community hospital in Ogden, Utah. PATIENTS Ninety-one consecutive inpatients with noncardiac diagnoses at the time of emergent transfer to the ICU. We determined the time when each patient first met any of 11 pre-specified physiologic criteria. We classified patients as “slow transfer” when patients met a physiologic criterion 4 or more hours before transfer to the ICU. Patients were followed until discharge. INTERVENTIONS None. MEASUREMENTS In-hospital mortality, functional status at hospital discharge, hospital resources. MAIN RESULTS At the time when the first physiologic criterion was met on the ward, slow- and rapid-transfer patients were similar in terms of age, gender, diagnosis, number of days in hospital prior to ICU transfer, prehospital functional status, and APACHE II scores. By the time slow-transfer patients were admitted to the ICU, they had significantly higher APACHE II scores (21.7 vs 16.2; P = .002) and were more likely to die in-hospital (41% vs 11%; relative risk [RR], 3.5; 95% confidence interval [95% CI], 1.4 to 9.5). Slow-transfer patients were less likely to have had their physician notified of deterioration within 2 hours of meeting physiologic criteria (59% vs 31%; P = .001) and less likely to have had a bedside physician evaluation within the first 3 hours after meeting criteria (23% vs 83%; P = .001). CONCLUSIONS Slow transfer to the ICU of physiologically defined high-risk hospitalized patients was associated with increased risk of death. Slow response to physiologic deterioration may explain these findings. PMID:12542581

  7. Exciton transfer dynamics in a trimer system

    Institute of Scientific and Technical Information of China (English)

    Tan Qing-Shou; Xu Lan; Kuang Le-Man

    2013-01-01

    We study exciton transfer dynamics in a trimer system by investigating excitation transfer probability (ETP).We calculate ETP in the zero-temperature limit and theoretically predict the environment-assisted quantum critical effect,in which ETP exhibits a sudden change at the critical point of quantum phase transition for the trimer.In particular,we find that the steady-state ETP can be observed in the presence of the environment interaction.

  8. Long-range charge transfer in biopolymers

    Science.gov (United States)

    Astakhova, T. Yu; Likhachev, V. N.; Vinogradov, G. A.

    2012-11-01

    The results of theoretical and experimental studies on the charge transfer in biopolymers, namely, DNA and peptides, are presented. Conditions that ensure the efficient long-range charge transport (by several tens of nanometres) are considered. The known theoretical models of charge transfer mechanisms are discussed and the scopes of their application are analyzed. Attention is focused on the charge transport by the polaron mechanism. The bibliography includes 262 references.

  9. Multichannel transfer function with dimensionality reduction

    KAUST Repository

    Kim, Han Suk

    2010-01-17

    The design of transfer functions for volume rendering is a difficult task. This is particularly true for multi-channel data sets, where multiple data values exist for each voxel. In this paper, we propose a new method for transfer function design. Our new method provides a framework to combine multiple approaches and pushes the boundary of gradient-based transfer functions to multiple channels, while still keeping the dimensionality of transfer functions to a manageable level, i.e., a maximum of three dimensions, which can be displayed visually in a straightforward way. Our approach utilizes channel intensity, gradient, curvature and texture properties of each voxel. The high-dimensional data of the domain is reduced by applying recently developed nonlinear dimensionality reduction algorithms. In this paper, we used Isomap as well as a traditional algorithm, Principle Component Analysis (PCA). Our results show that these dimensionality reduction algorithms significantly improve the transfer function design process without compromising visualization accuracy. In this publication we report on the impact of the dimensionality reduction algorithms on transfer function design for confocal microscopy data.

  10. Transfer of DNA from Bacteria to Eukaryotes

    Directory of Open Access Journals (Sweden)

    Benoît Lacroix

    2016-07-01

    Full Text Available Historically, the members of the Agrobacterium genus have been considered the only bacterial species naturally able to transfer and integrate DNA into the genomes of their eukaryotic hosts. Yet, increasing evidence suggests that this ability to genetically transform eukaryotic host cells might be more widespread in the bacterial world. Indeed, analyses of accumulating genomic data reveal cases of horizontal gene transfer from bacteria to eukaryotes and suggest that it represents a significant force in adaptive evolution of eukaryotic species. Specifically, recent reports indicate that bacteria other than Agrobacterium, such as Bartonella henselae (a zoonotic pathogen, Rhizobium etli (a plant-symbiotic bacterium related to Agrobacterium, or even Escherichia coli, have the ability to genetically transform their host cells under laboratory conditions. This DNA transfer relies on type IV secretion systems (T4SSs, the molecular machines that transport macromolecules during conjugative plasmid transfer and also during transport of proteins and/or DNA to the eukaryotic recipient cells. In this review article, we explore the extent of possible transfer of genetic information from bacteria to eukaryotic cells as well as the evolutionary implications and potential applications of this transfer.

  11. Technology transfer — bridging space and society

    Science.gov (United States)

    Students of Technology Transfer Design Project Team (ISU Summer Session 1997)

    Strategies, policies and methods by which technologies can be cross-fertilized between the space and non-space sectors were examined by students of the design project "Technology Transfer — Bridging Space and Society". This project was undertaken by students attending the 1997 10th Anniversary Summer Session Program of the International Space University. General issues relating to transfer of technology were discussed including definitions and mechanisms (push, pull, interactive and pro-active). As well as looking at case studies and the impact of national policies on space agencies, the design project also sought to look at technology transfer on a country-by-country basis, selecting various countries for scrutiny and reporting on their technology transfer status. The project report shows how transfer of technology varies between nations and when analyzed with the case studies identifies the general strategies, policies and methods in use and how they can be improved. Finally, the report seeks to recommend certain issues to governments, space agencies and industrial organizations to facilitate the transfer of technology. These include the development of a generic metrics system and the implementation of better appropriate procedures and mechanisms for a positive diffusion process between space and non-space sectors.

  12. Microwork transfer system in a nanomanufacturing world

    Science.gov (United States)

    Tsuchiya, Kensuke; Nakao, Masayuki; Okusa, Takenori; Hatamura, Yotaro; Matsumoto, Kiyoshi

    1998-01-01

    Practical micromachines, such as magnetic heads or endoscopic tools, can not be made only by shaping processes; they require post-machining processes such as assembling, wiring, piping, etc. The authors have developed an integrated manufacturing system, 'nano manufacturing world' (NMW). It performs shaping, post-machining or transferring like a factory. In this paper, we introduce a microwork transfer system, which functions a) steady transfer of a workpiece, b) non-release chucking of the workpiece during production and c) individual rotation of the workpiece using a preloaded microslide bearing on the pallet. Developed transfer system could realize the functions: less positioning error due to accurate pallet positioning by taper pins, high transfer yield of the workpieces due to no missing by a micro chuck, sub-micron rotational fluctuation due to a roller pallet by a preloaded micro slide bearing. Through the fabrication demonstrations of a sub-1 mm3 micro-house or micro force sensor block of 125 X 100 X 500 micrometers , it has been confirmed that this transfer system improved the performance of integrated manufacturing in NMW.

  13. Powering physics data transfers with FDT

    CERN Document Server

    Maxa, Zdenek

    2011-01-01

    We present a data transfer system for the grid environment built on top of the open source FDT tool (Fast Data Transfer) developed by Caltech in collaboration with the National University of Science and Technology (Pakistan). The enhancement layer above FDT consists of a client program - fdtcp (FDT copy) and a fdtd service (FDT daemon). This pair of components allows for GSI authenticated data transfers and offers to the user (or data movement production service) interface analogous to grid middle-ware data transfer services - SRM (i.e. srmcp) or GridFTP (i.e. globus-url-copy). fdtcp/fdtd enables third-party, batched file transfers. An important aspect is monitoring by means of the MonALISA active monitoring light-weight library ApMon, providing real-time monitoring and arrival time estimates as well as powerful troubleshooting mechanism. The actual transfer is carried out by the FDT application, an efficient application capable of reading and writing at disk speed over wide area networks. FDT?s excellent per...

  14. Optimal Low Energy Earth-Moon Transfers

    Science.gov (United States)

    Griesemer, Paul Ricord; Ocampo, Cesar; Cooley, D. S.

    2010-01-01

    The optimality of a low-energy Earth-Moon transfer is examined for the first time using primer vector theory. An optimal control problem is formed with the following free variables: the location, time, and magnitude of the transfer insertion burn, and the transfer time. A constraint is placed on the initial state of the spacecraft to bind it to a given initial orbit around a first body, and on the final state of the spacecraft to limit its Keplerian energy with respect to a second body. Optimal transfers in the system are shown to meet certain conditions placed on the primer vector and its time derivative. A two point boundary value problem containing these necessary conditions is created for use in targeting optimal transfers. The two point boundary value problem is then applied to the ballistic lunar capture problem, and an optimal trajectory is shown. Additionally, the ballistic lunar capture trajectory is examined to determine whether one or more additional impulses may improve on the cost of the transfer.

  15. Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: The mouse homologs of genes respondible for glutaric acidemia type II in human

    Energy Technology Data Exchange (ETDEWEB)

    White, R.A.; Dowler, L.L.; Angeloni, S.V. [UMKC School of Medicine, Kansas City, MO (United States); Koeller, D.M. [Univ. of Colorado Health Sciences Center, Denver, CO (United States)

    1996-04-01

    Electron transfer flavoprotein (composed of {alpha} and {beta} subunits) is an obligatory electron acceptor for several dehydrogenases and is located in the mitochondrial matrix. Electrons accepted by electron transfer flavo-protein (ETF) are transferred to the main mitochondrial respiratory chain by the way of ETF dehydrogenase (ETFDH). In humans, deficiency of ETF or ETFDH leads to glutaric acidemia type II, an inherited metabolic disorder that can be fatal in its neonatal form and is characterized by severe hypoketotic hypoglycemia and acidosis. We used cDNA probes for the Etfdh, Etfb, and Etfa genes to determine localization of these mouse genes to chromosomes 3, 7, and 13. 18 refs., 3 figs.

  16. An Analysis on Mother Tongue Transfer in Second Language Acquisition

    Institute of Scientific and Technical Information of China (English)

    李可喻

    2016-01-01

    Mother tongue transfer is a common phenomenon in learning the second language. It’s tends to produce two-side influences upon Second Language acquisition, namely, positive transfer and negative transfer. This paper firstly dwells on the background of Linguistic transfer, and then analysis the positive transfer and negative transfer in phonological and syntax, finally gives some suggestion for second language learning and teaching.

  17. An Integrative Review Of 2/4 Transfer Programs

    OpenAIRE

    Timothy A. DuPont

    2011-01-01

    This integrative review paper examines the most recent research data as it pertains to transfer programs between two-year and four-year colleges in the United States. This examination is guided by the research question: What are the suggested components of a quality transfer program? Suggested components of transfer programs are Transfer Centers which provide one location for transfer student services. These services should include: (a) advising services; (b) pre-transfer orientation programs...

  18. Heat transfer behavior of molten nitrate salt

    Science.gov (United States)

    Das, Apurba K.; Clark, Michael M.; Teigen, Bard C.; Fiveland, Woodrow A.; Anderson, Mark H.

    2016-05-01

    The usage of molten nitrate salt as heat transfer fluid and thermal storage medium decouples the generation of electricity from the variable nature of the solar resource, allowing CSP plants to avoid curtailment and match production with demand. This however brings some unique challenges for the design of the molten salt central receiver (MSCR). An aspect critical to the use of molten nitrate (60wt%/40wt% - NaNO3/KNO3) salt as heat transfer fluid in the MSCR is to understand its heat transfer behavior. Alstom collaborated with the University of Wisconsin to conduct a series of experiments and experimentally determined the heat transfer coefficients of molten nitrate salt up to high Reynolds number (Re > 2.0E5) and heat flux (q″ > 1000 kW/m2), conditions heretofore not reported in the literature. A cartridge heater instrumented with thermocouples was installed inside a stainless steel pipe to form an annular test section. The test section was installed in the molten salt flow loop at the University of Wisconsin facility, and operated over a range of test conditions to determine heat transfer data that covered the expected operating regime of a practical molten salt receiver. Heat transfer data were compared to widely accepted correlations found in heat transfer literature, including that of Gnielinski. At lower Reynolds number conditions, the results from this work concurred with the molten salt heat transfer data reported in literature and followed the aforementioned correlations. However, in the region of interest for practical receiver design, the correlations did not accurately model the experimentally determined heat transfer data. Two major effects were observed: (i) all other factors remaining constant, the Nusselt numbers gradually plateaued at higher Reynolds number; and (ii) at higher Reynolds number a positive interaction of heat flux on Nusselt number was noted. These effects are definitely not modeled by the existing correlations. In this paper a new

  19. Proton-Coupled Electron Transfer Reactions with Photometric Bases Reveal Free Energy Relationships for Proton Transfer.

    Science.gov (United States)

    Eisenhart, Thomas T; Howland, William C; Dempsey, Jillian L

    2016-08-18

    The proton-coupled electron transfer (PCET) oxidation of p-aminophenol in acetonitrile was initiated via stopped-flow rapid-mixing and spectroscopically monitored. For oxidation by ferrocenium in the presence of 7-(dimethylamino)quinoline proton acceptors, both the electron transfer and proton transfer components could be optically monitored in the visible region; the decay of the ferrocenium absorbance is readily monitored (λmax = 620 nm), and the absorbance of the 2,4-substituted 7-(dimethylamino)quinoline derivatives (λmax = 370-392 nm) red-shifts substantially (ca. 70 nm) upon protonation. Spectral analysis revealed the reaction proceeds via a stepwise electron transfer-proton transfer process, and modeling of the kinetics traces monitoring the ferrocenium and quinolinium signals provided rate constants for elementary proton and electron transfer steps. As the pKa values of the conjugate acids of the 2,4-R-7-(dimethylamino)quinoline derivatives employed were readily tuned by varying the substituents at the 2- and 4-positions of the quinoline backbone, the driving force for proton transfer was systematically varied. Proton transfer rate constants (kPT,2 = (1.5-7.5) × 10(8) M(-1) s(-1), kPT,4 = (0.55-3.0) × 10(7) M(-1) s(-1)) were found to correlate with the pKa of the conjugate acid of the proton acceptor, in agreement with anticipated free energy relationships for proton transfer processes in PCET reactions. PMID:27500804

  20. Excited-State-Proton-Transfer-Triggered Fluorescence Resonance Energy Transfer: from 2-Naphthylamine to Phenosafranin

    Science.gov (United States)

    Ghosh, Debanjana; Bose, Debosreeta; Sarkar, Deboleena; Chattopadhyay, Nitin

    2009-09-01

    Excited-state proton transfer (ESPT) and fluorescence resonance energy transfer (FRET) have been linearly coupled leading to an efficient pH-sensitive energy transfer from 2-naphthylamine (2NA) to a potentially bioactive cationic phenazinium dye, phenosafranin (PSF). The prototropic product produced exclusively from the photoexcited 2NA in the presence of added alkali serves as the donor for the energy transfer process. The energy transfer process is turned on at pH ≥ 12, whereas the process is turned off at a pH lower than that. Within the range of pH 12 to 13, the energy transfer efficiency (E) has been shown to follow a linear relation with the solution pH establishing the governing role of pH of the solution on the energy transfer process. The energy transfer follows a long-range dipole-dipole interaction mechanism. The critical energy transfer distance (R0) and the distance between the acceptor and the donor (r) have been determined for the ESPT-promoted FRET process at an optimum pH of 13. The present study involving the coupled processes is simple but has its implication due to its potential to be exploited for designing a pH-sensitive molecular switch.