WorldWideScience

Sample records for beryllium good practice

  1. Defense programs beryllium good practice guide

    International Nuclear Information System (INIS)

    Within the DOE, it has recently become apparent that some contractor employees who have worked (or are currently working) with and around beryllium have developed chronic beryllium disease (CBD), an occupational granulomatous lung disorder. Respiratory exposure to aerosolized beryllium, in susceptible individuals, causes an immunological reaction that can result in granulomatous scarring of the lung parenchyma, shortness of breath, cough, fatigue, weight loss, and, ultimately, respiratory failure. Beryllium disease was originally identified in the 1940s, largely in the fluorescent light industry. In 1950, the Atomic Energy Commission (AEC) introduced strict exposure standards that generally curtailed both the acute and chronic forms of the disease. Beginning in 1984, with the identification of a CBD case in a DOE contractor worker, there was increased scrutiny of both industrial hygiene practices and individuals in this workforce. To date, over 100 additional cases of beryllium-specific sensitization and/or CBD have been identified. Thus, a disease previously thought to be largely eliminated by the adoption of permissible exposure standards 45 years ago is still a health risk in certain workforces. This good practice guide forms the basis of an acceptable program for controlling workplace exposure to beryllium. It provides (1) Guidance for minimizing worker exposure to beryllium in Defense Programs facilities during all phases of beryllium-related work, including the decontamination and decommissioning (D ampersand D) of facilities. (2) Recommended controls to be applied to the handling of metallic beryllium and beryllium alloys, beryllium oxide, and other beryllium compounds. (3) Recommendations for medical monitoring and surveillance of workers exposed (or potentially exposed) to beryllium, based on the best current understanding of beryllium disease and medical diagnostic tests available. (4) Site-specific safety procedures for all processes of beryllium that is

  2. Defense programs beryllium good practice guide

    Energy Technology Data Exchange (ETDEWEB)

    Herr, M.

    1997-07-01

    Within the DOE, it has recently become apparent that some contractor employees who have worked (or are currently working) with and around beryllium have developed chronic beryllium disease (CBD), an occupational granulomatous lung disorder. Respiratory exposure to aerosolized beryllium, in susceptible individuals, causes an immunological reaction that can result in granulomatous scarring of the lung parenchyma, shortness of breath, cough, fatigue, weight loss, and, ultimately, respiratory failure. Beryllium disease was originally identified in the 1940s, largely in the fluorescent light industry. In 1950, the Atomic Energy Commission (AEC) introduced strict exposure standards that generally curtailed both the acute and chronic forms of the disease. Beginning in 1984, with the identification of a CBD case in a DOE contractor worker, there was increased scrutiny of both industrial hygiene practices and individuals in this workforce. To date, over 100 additional cases of beryllium-specific sensitization and/or CBD have been identified. Thus, a disease previously thought to be largely eliminated by the adoption of permissible exposure standards 45 years ago is still a health risk in certain workforces. This good practice guide forms the basis of an acceptable program for controlling workplace exposure to beryllium. It provides (1) Guidance for minimizing worker exposure to beryllium in Defense Programs facilities during all phases of beryllium-related work, including the decontamination and decommissioning (D&D) of facilities. (2) Recommended controls to be applied to the handling of metallic beryllium and beryllium alloys, beryllium oxide, and other beryllium compounds. (3) Recommendations for medical monitoring and surveillance of workers exposed (or potentially exposed) to beryllium, based on the best current understanding of beryllium disease and medical diagnostic tests available. (4) Site-specific safety procedures for all processes of beryllium that is likely to

  3. Good Practice Guides

    OpenAIRE

    Public Health Agency

    2010-01-01

    This series of Good Practice Guides is designed to share important information about health inequalities and some of the evidence-based measures that can be taken to reduce the stark differences in health and wellbeing within populations.

  4. Good Laboratory Practice

    Science.gov (United States)

    Hadjicostas, Evsevios

    The principles of Good Laboratory Practice (GLP) in conjunction with the principles of Total Quality Management (see chapter 6) ensure the quality and reliability of the laboratory results, which in turn help to ensure the protection of the environment and human health and safety. A step further is the accreditation of laboratories to ISO 17025 (see chapter 2) to perform specified activities.

  5. Good Practice Guides

    OpenAIRE

    Public Health Agency

    2010-01-01

    This series of Good Practice Guides is designed to share important information about health inequalities and some of the evidence-based measures that can be taken to reduce the stark differences in health and wellbeing within populations. It is recognised that leadership and coordinated, effective action at a number of levels can reduce this gap. Ensuring concerted, evidence-based action on health and wellbeing inequalities demands the efforts of government, statutory organisations and the co...

  6. Good practices in de 'spotlight'

    NARCIS (Netherlands)

    Leendertse, P.; Wijnands, F.G.

    2010-01-01

    Vanuit de projecten ‘Duurzaam telen, begint bij jou’ en ‘Telen met Toekomst’ is gezamenlijk een keuze gemaakt om per sector vijf Good Practices extra onder de aandacht te brengen. Per sector aandacht voor gewasbescherming en teeltsystemen.

  7. Integrating Education: Parekhian Multiculturalism and Good Practice

    Science.gov (United States)

    McGlynn, Claire

    2009-01-01

    This paper explores the concept of good practice in integrating education in divided societies. Using Northern Ireland as a case study, the paper draws on data from eight schools (both integrated Catholic and Protestant, and separate) that are identified as exemplifying good practice in response to cultural diversity. Analysis is provided through…

  8. Good manufacturing practice on European fishing vessels

    NARCIS (Netherlands)

    Hopper, A.G.; Batista, I.; Nunes, M.L.; Abrantes, J.; Frismo, E.; Slotten, van P.; Schelvis-Smit, A.A.M.

    2003-01-01

    A compilation is presented of seven contributions from fishermen or representatives from National Fishermen's Organisations about Good Manufacturing Practice (GMP) on board of vessels in Portugal, Norway, the Netherlands, Italy, Spain, France and United Kingdom

  9. GOOD PRACTICE UNDER THE UNIVERSITY SOCIAL RESPONSIBILITY

    Directory of Open Access Journals (Sweden)

    Myrna D. López-Noriega

    2015-07-01

    Full Text Available In this document we analyzed the progress of the good practices of university social responsibility (USR in higher education, considering the case of the Universidad Autónoma del Carmen (UNACAR. We made an inventory of good practices at the institutional level and also about his Faculty of Administratives and Economics Sciences; these were classified according in a matrix based on the impacts on the environment. The analysis of institutional documents shows that in the UNACAR the RSU is linked to concepts such as sustainable development and regional development, as a result of its location within the National Protected Area of Flora and Fauna Laguna de Términos.

  10. Wind Farms Community Engagement Good Practice Review

    DEFF Research Database (Denmark)

    Aitken, Mhairi; Haggett, Claire; Rudolph, David Philipp

    2016-01-01

    This report sets out the findings of a review of community engagement for wind farm developments. We focus in particular on the engagement carried out by developers with communities. The aims of the study were to evaluate current good practice for engaging people in decision making about on......- and offshore wind farms in different European countries; to evaluate the effect that different practices have on public opinion and acceptance; and to make relevant recommendations for Scottish policy and planning....

  11. Beryllium chemistry and processing

    CERN Document Server

    Walsh, Kenneth A

    2009-01-01

    This book introduces beryllium; its history, its chemical, mechanical, and physical properties including nuclear properties. The 29 chapters include the mineralogy of beryllium and the preferred global sources of ore bodies. The identification and specifics of the industrial metallurgical processes used to form oxide from the ore and then metal from the oxide are thoroughly described. The special features of beryllium chemistry are introduced, including analytical chemical practices. Beryllium compounds of industrial interest are identified and discussed. Alloying, casting, powder processing, forming, metal removal, joining and other manufacturing processes are covered. The effect of composition and process on the mechanical and physical properties of beryllium alloys assists the reader in material selection. The physical metallurgy chapter brings conformity between chemical and physical metallurgical processing of beryllium, metal, alloys, and compounds. The environmental degradation of beryllium and its all...

  12. Tourism. Leonardo da Vinci Series: Good Practices.

    Science.gov (United States)

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This brochure, part of a series about good practices in vocational training in the European Union, describes 10 projects that have promoted investment in human resources through training in the tourism sector to promote sustainable, or responsible, tourism. The projects and their countries of origin are as follows: (1) BEEFT, training of mobility…

  13. Good Practice Standards – a Regulation Tool

    DEFF Research Database (Denmark)

    Sørensen, Marie Jull

    2013-01-01

    The purpose of this article is to identify the considerations weighed in regulation with good practice standards. In this article, potential due process problems with regulation via legal standards are identified and compared to other considerations, which this regulation technique meets....

  14. Good Agricultural Practices of Enicostemma axillare

    OpenAIRE

    Abirami, K.

    2015-01-01

    The paper reports the Good Agricultural Practices (GAP) of Enicostema axillare ( Lam. ) A. Raynal(= Enicostemma littorale   auct. non Blume). Details of the GAP  which includes growing environment, soil type, propagation material, nursery technique, transplanting details, manure application, optimum spacing,  Intercultural operations, harvest and post harvest management are described along with a calendar of operation schedule.  

  15. Good practices in early childhood education:

    DEFF Research Database (Denmark)

    Sanders, Lise; Gregoriadis, Athanasis; Zachopoulou, Evridiki;

    Good practices in early childhood education er en undersøgelse fortaget efter Early Childhood Environmental Rating Scale - R (ECERS-R). I undersøgelsen deltog Akademikere, pædagoger og kommunalt personale fra de 6 partnerlande bestående af Grækenland, Portugal, Finland, Danmark, Rumænien og Cyper...

  16. Guide to good practices for communications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    This Guide to Good Practices is written to enhance understanding of, and provide direction for, Communications, Chapter 4 of Department of Energy (DOE) Order 5480.19, Conduct of Operations Requirements for DOE Facilities. The practices in this guide should be considered when planning or reviewing communication programs. Contractors are advised to adopt procedures that meet the intent of DOE Order 5480.19. ``Communications`` is an element of an effective Conduct of Operations program. The complexity and array of activities performed in DOE facilities dictate the necessity for high reliability in communications to promote safe and efficient operations.

  17. Good clinical practices in phase I studies.

    Science.gov (United States)

    Decousus, H; Perpoint, B; Mismetti, P; Ollagnier, M; Queneau, P

    1990-01-01

    In France, official guidelines for good clinical practices in clinical trials were issued in 1987. In December 1988, a law was passed that fixed the requirements for carrying out experiments in healthy subjects. It will be completed by official guidelines for the structures in which experiments on healthy subjects (and patients as well, when the investigation would not benefit the health of the patients) may be conducted. Hence a battery of recent legal instructions precisely state what good clinical practices are in the setting of phase I studies. Of particular importance are: subject recruitment and selection methods and procedures; specific competence of the investigator, in particular to interpret the pre-trial data; necessary and sufficient facilities to guarantee the subjects' safety; careful quality control to check all laboratory procedures; necessity of written standard operating procedures.

  18. Good manufacturing practice - quality assurance programs

    International Nuclear Information System (INIS)

    The concept of good manufacturing practice (GMP) in the medical device industry requires the use of controlled methods and equipment in performing each step in the device manufacturing process. Quality assurance programs are used to maintain compliance with GMP requirements by prescribing the operating and control procedures to be used. The specific elements of a quality assurance program for the radiation sterilization of medical devices are described. (author)

  19. Good Agricultural Practices of Enicostemma axillare

    Directory of Open Access Journals (Sweden)

    K Abirami

    2015-02-01

    Full Text Available The paper reports the Good Agricultural Practices (GAP of Enicostema axillare ( Lam. A. Raynal(= Enicostemma littorale   auct. non Blume. Details of the GAP  which includes growing environment, soil type, propagation material, nursery technique, transplanting details, manure application, optimum spacing,  Intercultural operations, harvest and post harvest management are described along with a calendar of operation schedule.  

  20. Microbiological criteria for good manufacturing practice (GMP)

    International Nuclear Information System (INIS)

    Good manufacturing practice (GMP) consist of an effective manufacturing operation and an effective application of food control. GMP is best supported by the Hazard Analysis Critical Control Point system (HACCP) of the preventive quality assurance, which requires that food irradiation as any food processing technology should be used only with foods of an acceptable quality and adequate handling and storage procedures should precede and follow the processing. The paper concentrates on the first element of the HACCP system for an irradiation plant: the incoming product control, i.e. whether GMP of foods to be irradiated can be assessed by establishing microbiological criteria for their previous good manufacturing practice. In this regard, it summarizes considerations and findings of a ''Consultation on Microbiological Criteria for Foods to be Further Processed Including by Irradiation'' held in 1989 by the International Consultative Group on Food irradiation at the Headquarters of the World Health Organization, Geneva. Difficulties in establishing reference values and defining good manufacturing practices will be pointed out. (orig.)

  1. Microbiological criteria for good manufacturing practice (GMP)

    Energy Technology Data Exchange (ETDEWEB)

    Farkas, J. (Inst. of Preservation and Livestock Products Technology, Univ. of Horticulture and Food Industry, Budapest (Hungary)); Zukal, E. (Inst. of Preservation and Livestock Products Technology, Univ. of Horticulture and Food Industry, Budapest (Hungary))

    1992-01-01

    Good manufacturing practice (GMP) consist of an effective manufacturing operation and an effective application of food control. GMP is best supported by the Hazard Analysis Critical Control Point system (HACCP) of the preventive quality assurance, which requires that food irradiation as any food processing technology should be used only with foods of an acceptable quality and adequate handling and storage procedures should precede and follow the processing. The paper concentrates on the first element of the HACCP system for an irradiation plant: the incoming product control, i.e. whether GMP of foods to be irradiated can be assessed by establishing microbiological criteria for their previous good manufacturing practice. In this regard, it summarizes considerations and findings of a ''Consultation on Microbiological Criteria for Foods to be Further Processed Including by Irradiation'' held in 1989 by the International Consultative Group on Food irradiation at the Headquarters of the World Health Organization, Geneva. Difficulties in establishing reference values and defining good manufacturing practices will be pointed out. (orig.)

  2. Good Practices in Free-energy Calculations

    Science.gov (United States)

    Pohorille, Andrew; Jarzynski, Christopher; Chipot, Christopher

    2013-01-01

    As access to computational resources continues to increase, free-energy calculations have emerged as a powerful tool that can play a predictive role in drug design. Yet, in a number of instances, the reliability of these calculations can be improved significantly if a number of precepts, or good practices are followed. For the most part, the theory upon which these good practices rely has been known for many years, but often overlooked, or simply ignored. In other cases, the theoretical developments are too recent for their potential to be fully grasped and merged into popular platforms for the computation of free-energy differences. The current best practices for carrying out free-energy calculations will be reviewed demonstrating that, at little to no additional cost, free-energy estimates could be markedly improved and bounded by meaningful error estimates. In energy perturbation and nonequilibrium work methods, monitoring the probability distributions that underlie the transformation between the states of interest, performing the calculation bidirectionally, stratifying the reaction pathway and choosing the most appropriate paradigms and algorithms for transforming between states offer significant gains in both accuracy and precision. In thermodynamic integration and probability distribution (histogramming) methods, properly designed adaptive techniques yield nearly uniform sampling of the relevant degrees of freedom and, by doing so, could markedly improve efficiency and accuracy of free energy calculations without incurring any additional computational expense.

  3. Agronomy, sustainability and good agricultural practices

    Directory of Open Access Journals (Sweden)

    Caliman Jean-Pierre

    2005-03-01

    Full Text Available Sustainable palm oil production needs to be based on the application of a code of good practices, respecting a certain number of criteria related to economic, environmental and social aspects. We focus here on economic and environmental aspects, attempting to take stock of the current situation regarding the management of inputs (fertilizers, pesticides, and of oil mill waste (empty fruit bunches, effluent. We also take a look at the main agricultural research required if we are to be able to assess the situation on different scales and see how it is evolving, and also provide assistance for rational management that is compatible with farmers’ production targets.

  4. Charter of good practices in industrial radiography

    International Nuclear Information System (INIS)

    This document describes good practices in the field of industrial radiography. After having presented the main prevention and radiation protection principles, the actors inside and outside of the company, and actors intervening during an operation subcontracting in industrial radiography, this report analyzes the activity: prerequisites for work preparation, prevention coordination, work preparation, transportation, work achievement, return on experience. It addresses personnel training and information, and the dosimetric and medical monitoring of technicians in industrial radiography. Some aspects are addressed in appendix: principles (justification, optimization, and limitation), regulations, intervention form, exposure form, and so on

  5. OSART good practices: 1986-1989

    International Nuclear Information System (INIS)

    The IAEA Operational Safety Review Team (OSART) programme provides advice and assistance to Member States for enhancing the operational safety of nuclear power plants (NPP). OSART teams started to identify good practices (GP), as examples of excellence in NPP operation, in 1986. This report is the first of its kind and summarizes GP for the period January 1986 to June 1989. The information in the report is presented in three different ways to facilitate access: The table of contents which present the GP at the NPP visited by OSART teams in the order of visits; the listing of the GP according to the eight standard areas of review, giving the NPP concerned and the relevant report page; the permutated index of the titles of the GP. 1 tab

  6. Good Laboratory Practice. Part 3. Implementing Good Laboratory Practice in the Analytical Lab

    Science.gov (United States)

    Wedlich, Richard C.; Pires, Amanda; Fazzino, Lisa; Fransen, Joseph M.

    2013-01-01

    Laboratories submitting experimental results to the Food and Drug Administration (FDA) or the Environmental Protection Agency (EPA) in support of Good Laboratory Practice (GLP) nonclinical laboratory studies must conduct such work in compliance with the GLP regulations. To consistently meet these requirements, lab managers employ a "divide…

  7. Beryllium 1989

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    The Roskill report on beryllium gives information on the occurrence and reserves, production technology, geographic distribution, consumption and end-uses, stocks, prices and beryllium and health. There is an appendix on international trade statistics. (author).

  8. 21 CFR 110.5 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 110.5 Section...) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKING, OR HOLDING HUMAN FOOD General Provisions § 110.5 Current good manufacturing practice. (a) The criteria...

  9. 21 CFR 226.1 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Current good manufacturing practice. 226.1 Section...) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES General Provisions § 226.1 Current good manufacturing practice. (a) The criteria in §§ 226.10 through 226.115,...

  10. 21 CFR 225.1 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Current good manufacturing practice. 225.1 Section...) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS General Provisions § 225.1 Current good manufacturing practice. (a) Section 501(a)(2)(B) of the Federal Food, Drug, and Cosmetic...

  11. Rules for the certification of good practices in clinical laboratories. No regulation. 3-2009. Good Laboratory Practice

    International Nuclear Information System (INIS)

    Regulation for Certification of Good Practices in clinical laboratories, hereinafter Regulation establishes the methodology and procedures for clinical laboratories to demonstrate their state of compliance with good practices, according to Regulation 3-2009, and that the CECMED can verify.

  12. Good practices in heavy water reactor operation

    International Nuclear Information System (INIS)

    The value and importance of organizations in the nuclear industry engaged in the collection and analysis of operating experience and best practices has been clearly identified in various IAEA publications and exercises. Both facility safety and operational efficiency can benefit from such information sharing. Such sharing also benefits organizations engaged in the development of new nuclear power plants, as it provides information to assist in optimizing designs to deliver improved safety and power generation performance. In cooperation with Atomic Energy of Canada, Ltd, the IAEA organized the workshop on best practices in Heavy Water Reactor Operation in Toronto, Canada from 16 to 19 September 2008, to assist interested Member States in sharing best practices and to provide a forum for the exchange of information among participating nuclear professionals. This workshop was organized under Technical Cooperation Project INT/4/141, on Status and Prospects of Development for and Applications of Innovative Reactor Concepts for Developing Countries. The workshop participants were experts actively engaged in various aspects of heavy water reactor operation. Participants presented information on activities and practices deemed by them to be best practices in a particular area for consideration by the workshop participants. Presentations by the participants covered a broad range of operational practices, including regulatory aspects, the reduction of occupational dose, performance improvements, and reducing operating and maintenance costs. This publication summarizes the material presented at the workshop, and includes session summaries prepared by the chair of each session and papers submitted by the presenters

  13. Good Manufacturing Practices (GMP) / Good Laboratory Practices (GLP) Review and Applicability for Chemical Security Enhancements

    Energy Technology Data Exchange (ETDEWEB)

    Iveson, Steven W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). International Chemical Security Threat Reduction

    2014-11-01

    Global chemical security has been enhanced through the determined use and integration of both voluntary and legislated standards. Many popular standards contain components that specifically detail requirements for the security of materials, facilities and other vital assets. In this document we examine the roll of quality management standards and how they affect the security culture within the institutions that adopt these standards in order to conduct business within the international market place. Good manufacturing practices and good laboratory practices are two of a number of quality management systems that have been adopted as law in many nations. These standards are designed to protect the quality of drugs, medicines, foods and analytical test results in order to provide the world-wide consumer with safe and affective products for consumption. These standards provide no established security protocols and yet manage to increase the security of chemicals, materials, facilities and the supply chain via the effective and complete control over the manufacturing, the global supply chains and testing processes. We discuss the means through which these systems enhance security and how nations can further improve these systems with additional regulations that deal specifically with security in the realm of these management systems. We conclude with a discussion of new technologies that may cause disruption within the industries covered by these standards and how these issues might be addressed in order to maintain or increase the level of security within the industries and nations that have adopted these standards.

  14. 21 CFR 129.1 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 129.1 Section... Current good manufacturing practice. The applicable criteria in part 110 of this chapter, as well as the... manufacturing practice to assure that bottled drinking water is safe and that it has been processed,...

  15. Construction quality management principles and good practice

    CERN Document Server

    Watson, Paul

    2011-01-01

    Quality management is essential for facilitating the competitiveness of modern day commercial organizations. Excellence in quality management is a requisite for construction organizations who seek to remain competitive and successful. The challenges presented by competitive construction markets and large projects that are dynamic and complex necessitate the adoption and application of quality management approaches. This textbook is written in line with the ISO 9001:2008 standard and provides a comprehensive evaluation of quality management systems and tools. Their effectiveness in achieving project objectives is explored, as well as applications in corporate performance enhancement. Both the strategic and operational dimensions of quality assurance are addressed by focusing on providing models of best practice. The reader is supported throughout by concise and clear explanations and with self-assessment questions. Practical case study examples show how various evaluative-based quality management systems and t...

  16. GOOD PRACTICE TIC. DIGITAL LITERACY IN OLDER

    Directory of Open Access Journals (Sweden)

    Félix Huelves Martín

    2010-12-01

    Full Text Available Computer equipment and their peripherals are designed for use by a single user, there is only one keyboard, only one mouse, and of course, a single screen. Therefore in the moment to provide a literacy class, the best option seems to be one computer per person. So each student seemed to learn more, have greater interaction with media, and therefore more learning time. But, Is it possible to have the number of computer needed for each student, always? Is it really essential the Single Computers in classroom for effective learning? Thanks to the experience in lot of adults´ literacy courses, using a methodology consistent with the goal of learning, we show a good formative experience, which although obvious, it allows us to realize factors such as the shortage of technological resources, adult psychology and the need to educate not only new technological capabilities but also to transmit values essential to ease management in the knowledge society.

  17. Uncertainty Communication. Issues and good practice

    International Nuclear Information System (INIS)

    In 2003 the Netherlands Environmental Assessment Agency (MNP) published the RIVM/MNP Guidance for Uncertainty Assessment and Communication. The Guidance assists in dealing with uncertainty in environmental assessments. Dealing with uncertainty is essential because assessment results regarding complex environmental issues are of limited value if the uncertainties have not been taken into account adequately. A careful analysis of uncertainties in an environmental assessment is required, but even more important is the effective communication of these uncertainties in the presentation of assessment results. The Guidance yields rich and differentiated insights in uncertainty, but the relevance of this uncertainty information may vary across audiences and uses of assessment results. Therefore, the reporting of uncertainties is one of the six key issues that is addressed in the Guidance. In practice, users of the Guidance felt a need for more practical assistance in the reporting of uncertainty information. This report explores the issue of uncertainty communication in more detail, and contains more detailed guidance on the communication of uncertainty. In order to make this a 'stand alone' document several questions that are mentioned in the detailed Guidance have been repeated here. This document thus has some overlap with the detailed Guidance. Part 1 gives a general introduction to the issue of communicating uncertainty information. It offers guidelines for (fine)tuning the communication to the intended audiences and context of a report, discusses how readers of a report tend to handle uncertainty information, and ends with a list of criteria that uncertainty communication needs to meet to increase its effectiveness. Part 2 helps writers to analyze the context in which communication takes place, and helps to map the audiences, and their information needs. It further helps to reflect upon anticipated uses and possible impacts of the uncertainty information on the

  18. Good ergonomic practices in a terminal facility

    Energy Technology Data Exchange (ETDEWEB)

    Anjos, Luciana Mattos dos; Curty, Adriana Favacho [CHEMTECH, Rio de Janeiro, RJ (Brazil); Franca, Guilherme Foerster do Monte; Jardino, Alessandro Neto [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

    2009-07-01

    Ergonomics is the technological design of the interplay between men, machines and environment in order to make labor activities more pleasant, profitable and functional. This article analyses the importance of ergonomic issues in process terminal plants and facilities, since the conceptual design stage until the detail engineering design. The ergonomic solutions are compared with practices that are current in engineering design plants nowadays. It will be shown how an inadequate ergonomic design often leads to accessibility problems and non-effectiveness during plant operation and dangers in emergency situations. The way perform an ergonomic design is to integrate the various disciplines that are involved in all stages of the design plant. The earlier the ergonomic design is implemented the better are the results in cost reduction, since later design modifications are more time-consuming and expensive. (author)

  19. A summarized discussion of current good manufacturing practice regulations.

    Science.gov (United States)

    Allen, Loyd V

    2013-01-01

    In light of recent events and discussions of compounding pharmacy, it is important to discuss and understand the purpose of good manufacturing practices. This article provides a summary of the current Good Manufacturing Practice Regulations which were established by the U.S. Food and Drug Administration.

  20. Understanding Graduate School Aspirations: The Effect of Good Teaching Practices

    Science.gov (United States)

    Hanson, Jana M.; Paulsen, Michael B.; Pascarella, Ernest T.

    2016-01-01

    This study examined the effects of good teaching practices on post-baccalaureate degree aspirations using logistic regression techniques on a multi-institutional, longitudinal sample of students at 4-year colleges and universities in the USA. We examined whether eight good teaching practices (non-classroom interactions with faculty, prompt…

  1. 21 CFR 113.5 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 113.5 Section 113.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... CONTAINERS General Provisions § 113.5 Current good manufacturing practice. The criteria in §§ 113.10,...

  2. 21 CFR 120.5 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 120.5 Section 120.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Provisions § 120.5 Current good manufacturing practice. Part 110 of this chapter applies in...

  3. Good practices for outage management in nuclear power plants

    International Nuclear Information System (INIS)

    As a follow-up to an earlier Technical Document on Good Practices for Improved Nuclear Power Plant Performance (IAEA-TECDOC-498), the Agency has produced a more focused technical report on good practices associated with nuclear power plant outage planning and execution. As with the earlier document, the overall aim is that by identifying good practices in the key aspects of outage management, overall world nuclear performance will improve and the gap between excellent performers and operators with developing programmes will be narrowed. This document has been produced through the contribution of numerous operators and government agencies. It aims at minimizing text and focusing on actual good practices in use which can be found in the annexes. While the specific methods used to achieve excellence in maintenance/refuelling outages may differ, the fundamental requirements of outage management are discussed

  4. Protection in the city: some good practice in Nairobi

    Directory of Open Access Journals (Sweden)

    Duncan Breen

    2013-04-01

    Full Text Available Despite a challenging protection environment, an NGO in Nairobi hasdeveloped an assistance programme for LGBTI refugees that offersexamples of good practice that could be replicated in other urban settings.

  5. Good Laboratory Practice (GLP). Study and Inspection Guidelines

    NARCIS (Netherlands)

    Strik; J.J.T.W.A.

    1986-01-01

    Good Laboratory Practice heeft betrekking op de organisatie van laboratoriumonderzoekingen en op de omstandigheden en voorwaarden waaronder deze studies worden opgezet, uitgevoerd, gevolgd, gegevens worden vastgelegd, de resultaten worden bewaard en gerapporteerd. In deze GLP handleiding worden

  6. Linking good agricultural practices and climate smart agriculture

    OpenAIRE

    Verhagen, A.; Hengsdijk, H.; Bezlepkina, I.; Groenestein, K.; Klooster, van 't, K.

    2013-01-01

    Recently, the concept of Climate Smart Agriculture (CSA) was introduced to position agriculture and food security in relation to climate change adaptation and mitigation. Good Agricultural Practices (GAP) with the aim to create cleaner and safer production systems and products has been around for a while. Because the goals of CSA and GAP ultimately need to be achieved by farmers it is logical to link and integrate CSA goals with Good Agricultural Practices (GAP). This report provides some ins...

  7. Good Operations Practice Supervisor Profiles in Cell-Centric Manufacturing

    OpenAIRE

    Tiwari, Ashutosh; Sackett, P.; Rehman, Shahwar; Linton, Howard

    2008-01-01

    Abstract The selection and implementation of good operations practice cannot be undertaken in isolation; it must consider the enterprise context. The aim of this paper is to describe a robust process for the development of specific environment good operations practice role profiles for supervisors, and illustrate this through a case study within a complex cell-centric manufacturing environment. The approach identifies the activities undertaken by a cell leader and team leader in ...

  8. TEACHER AND SCHOOL VARIABLES THAT GENERATE GOOD PRACTICES WITH ICT

    OpenAIRE

    Pilar Colás Bravo; Juan Casanova Correa

    2010-01-01

    In this article the results of a case study carried out are presented by means of narrative interviews, whose objective is to identify the determining factors of the good practices with ICT. The good practices with ICT are related to two scientific areas of study. One, above mentioned, related to the integration of the ICT in the educational systems and, another, connected with processes of innovation. In this contribution we present the state of the question related to determining fact...

  9. Beryllium Toxicity

    Science.gov (United States)

    ... Favorites Del.icio.us Digg Facebook Google Bookmarks Yahoo MyWeb Beryllium Toxicity Patient Education Care Instruction Sheet ... Favorites Del.icio.us Digg Facebook Google Bookmarks Yahoo MyWeb Page last reviewed: May 23, 2008 Page ...

  10. 21 CFR 114.5 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 114.5 Section 114.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION ACIDIFIED FOODS General Provisions § 114.5 Current good...

  11. 21 CFR 123.5 - Current good manufacturing practice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 123.5 Section 123.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... manufacturing practice. (a) Part 110 of this chapter applies in determining whether the facilities,...

  12. Health physics manual of good practices for tritium facilities

    International Nuclear Information System (INIS)

    The purpose of this document is to provide written guidance defining the generally accepted good practices in use at Department of Energy (DOE) tritium facilities. A open-quotes good practiceclose quotes is an action, policy, or procedure that enhances the radiation protection program at a DOE site. The information selected for inclusion in this document should help readers achieve an understanding of the key radiation protection issues at tritium facilities and provide guidance as to what characterizes excellence from a radiation protection point of view. The ALARA (As Low as Reasonable Achievable) program at DOE sites should be based, in part, on following the good practices that apply to their operations

  13. Good Corporate Governance And Earnings Management Practices: An Indonesian Cases

    OpenAIRE

    murhadi, werner R.

    2009-01-01

    This research is done for the purpose of finding out the effect of Good Governance practice can reduce earnings management practice done by company. This research uses companies registered in manufacture sector in Indonesia Stock Exchange observation period 2005-2007 as samples. Last sample used in this research is 384 years of observation. This research uses OLS method. The result shows that only two variables have significant effect to Earning Management practice which is CEO Duality and co...

  14. Sharing Good Practice through Mash-Up Personal Learning Environments

    Science.gov (United States)

    Mödritscher, Felix; Wild, Fridolin

    Personal learning environments (PLEs) require new ways to motivate and scaffold learners. In particular, practice sharing is of importance for learnercentric approaches in the scope of (technology-enhanced) lifelong learning, as it is an enabler for community building and sustaining. In this paper we elaborate prerequisites for ‘good practice sharing’ and explain how we realized these aspects in our PLE solution named Mash-Up Personal Learning Environments (MUPPLE.org). Finally, we argue for the utility of our MUPPLE approach by highlighting two different strategies of good practice sharing and their benefits for learning and community building.

  15. Health physics manual of good practices for tritium facilities

    Energy Technology Data Exchange (ETDEWEB)

    Blauvelt, R.K.; Deaton, M.R.; Gill, J.T. [and others

    1991-12-01

    The purpose of this document is to provide written guidance defining the generally accepted good practices in use at Department of Energy (DOE) tritium facilities. A {open_quotes}good practice{close_quotes} is an action, policy, or procedure that enhances the radiation protection program at a DOE site. The information selected for inclusion in this document should help readers achieve an understanding of the key radiation protection issues at tritium facilities and provide guidance as to what characterizes excellence from a radiation protection point of view. The ALARA (As Low as Reasonable Achievable) program at DOE sites should be based, in part, on following the good practices that apply to their operations.

  16. TEACHER AND SCHOOL VARIABLES THAT GENERATE GOOD PRACTICES WITH ICT

    Directory of Open Access Journals (Sweden)

    Pilar Colás Bravo

    2010-02-01

    Full Text Available In this article the results of a case study carried out are presented by means of narrative interviews, whose objective is to identify the determining factors of the good practices with ICT. The good practices with ICT are related to two scientific areas of study. One, above mentioned, related to the integration of the ICT in the educational systems and, another, connected with processes of innovation. In this contribution we present the state of the question related to determining factors of the good practices from both points of view. From there we situate the theoretical framework of this work since the perspective of the teachers. The qualitative analysis carried out by means of the program AtlasTi identifies personal and contextual factors associated to the processes of innovation.

  17. Hygiene and good manufacturing practice in terms of public health

    OpenAIRE

    Sibel CEVİZCİ; Ayşe Emel ÖNAL

    2009-01-01

    With globalization, presenting service and product which have good quality and conformity with hygienic regulations, have become more important in health, pharmacy and food sectors. That’s why the quality control and documentation systems which are also considerable in terms of public health, were about to change. Today, lots of companies especially in health sector, prefer “Good Manufacturing Practices (GMP)”- including a developed quality-hygiene control and documentation method - that they...

  18. GOOD PRACTICE AND SCIENTIFIC ASPECTS OF METHADONE MAINTENANCE TREATMENT

    Institute of Scientific and Technical Information of China (English)

    Ambros Uchtenhagen

    2010-01-01

    @@ Methadone maintenance treatment(MMT) is one of the best researched therapies in addiction medicine. The relevant factors for good outcome are identified: retention, adequate dosage policy, comprehensive assessment and treatment programme caring for all health and social needs of patients, patient-friendly non-punitive attitudes of staff. Detailed guidelines on good practice in MMT are based on research evidence and are helpful for knowledge transfer into practice. In a public health perspective and in the interest to cover as many opiate addicts as possible, minimal requirements should be met on the service level as well as on the treatment system level and the health policy level.

  19. Radiopharmaceuticals good practices handbook: ARCAL XV radiopharmaceuticals control and production

    International Nuclear Information System (INIS)

    A safety practice of the therapeutics diagnostic proceeding in nuclear medicine require a permanent provide high quality radiopharmaceuticals manufacture. This work treat to give a guide for all radio pharmacies laboratories that produce,control, fraction and or dispense radiopharmaceuticals products, with attention hospitable radiopharmacy laboratory. Three chapters with recommendations in manufacture good practice in Hospital radiopharmacy, industrial centralized, bibliography and three annexe's about clean area classification,standards work in laminar flux bell, and guarantee and cleaning areas

  20. Identifying critical factors for implementing good agricultural practice

    OpenAIRE

    Nelson Gutiérrez Guzmán; Juan Antonio Serra Belenguer; Gonzalo Clemente Marín

    2010-01-01

    This paper deals with identifying the critical factors (CFs) involved in implementing a good agricultural practice (GAP) programme for coffee and fruit farmers in the Huila department of Colombia. An exploratory factor analysis using principal component analy- sis (PCA) factorisation was used. Data matrixes were constructed from the results of applying two defined-structure assessment tools to the populations being studied: Starbucks’ coffee and farmer equity (CAFE) practices for small-scal...

  1. Robust data enables managers to promote good practice.

    Science.gov (United States)

    Bassett, Sally; Westmore, Kathryn

    2012-11-01

    This is the third in a series of articles examining the components of good corporate governance. The effective and efficient use of information and sources of information is crucial for good governance. This article explores the ways in which boards and management can obtain and use information to monitor performance and promote good practice, and how boards can be assured about the quality of information on which they rely. The final article in this series will look at the role of accountability in corporate governance. PMID:23189532

  2. Robust data enables managers to promote good practice.

    Science.gov (United States)

    Bassett, Sally; Westmore, Kathryn

    2012-11-01

    This is the third in a series of articles examining the components of good corporate governance. The effective and efficient use of information and sources of information is crucial for good governance. This article explores the ways in which boards and management can obtain and use information to monitor performance and promote good practice, and how boards can be assured about the quality of information on which they rely. The final article in this series will look at the role of accountability in corporate governance.

  3. Do board characteristics and good governance practices affect charity performance?

    NARCIS (Netherlands)

    F.H.M. Verbeeten; P. Perego

    2013-01-01

    In recent years there has been a proliferation of 'good governance' initiatives among charitable organizations to encourage increased accountability towards their stakeholders. Despite their diffusion, the efficacy of these best practice guides has not been object of extensive academic research. In

  4. The online good practice guide on job finding

    DEFF Research Database (Denmark)

    Levinsen, Karin Tweddell; Ørngreen, Rikke; Andreasen, Lars Birch

    2010-01-01

    The Online Good Practice Guide on Job Finding is a result of the project L@JOST, 'Learn about finding jobs through digital storytelling', with the purpose of enhancing the employability possibilities of graduated students through the use of e-portfolio and digital storytelling....

  5. Linking good agricultural practices and climate smart agriculture

    NARCIS (Netherlands)

    Verhagen, A.; Hengsdijk, H.; Bezlepkina, I.; Groenestein, K.; Klooster, van 't K.

    2013-01-01

    Recently, the concept of Climate Smart Agriculture (CSA) was introduced to position agriculture and food security in relation to climate change adaptation and mitigation. Good Agricultural Practices (GAP) with the aim to create cleaner and safer production systems and products has been around for a

  6. VET Providers Planning to Deliver Degrees: Good Practice Guide

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2015

    2015-01-01

    This good practice guide is intended to assist public and private registered training organisations (RTOs) planning to commence higher education (HE) delivery. The guide is based on research undertaken by Victor Callan and Kaye Bowman, who completed case studies with six providers currently delivering higher education qualifications in addition to…

  7. Guide to good practices for developing learning objectives. DOE guideline

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-01

    This guide to good practices provides information and guidance on the types of, and the development of learning objectives in performance-based training system at reactor and nonreactor nuclear facilities. Contractors are encouraged to consider this guidance as a reference when developing new learning objectives or refining existing ones. Training managers, designers, developers, and instructors are the intended audiences.

  8. Guide to good practices for developing learning objectives. DOE Handbook

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-07-01

    This guide to good practices provides information and guidance on the types of and development of learning objectives in a systematic approach to training program. This document can serve as a reference during the development of new learning objectives or refinement of existing ones.

  9. Knowledge Gained from Good Agricultural Practices Courses for Iowa Growers

    Science.gov (United States)

    Shaw, Angela; Strohbehn, Catherine; Naeve, Linda; Domoto, Paul; Wilson, Lester

    2015-01-01

    Good Agricultural Practices (GAP) educational courses provide produce growers with the fundamental information for producing and processing safe produce. To determine the effectiveness of the current 7-hour GAP course provided in Iowa, growers were surveyed before and 7-14 days after the course to determine changes in knowledge and opinions.…

  10. Good Laboratory Practice. Part 2. Recording and Retaining Raw Data

    Science.gov (United States)

    Wedlich, Richard C.; Libera, Agata E.; Pires, Amanda; Tellarini, Cassandra

    2013-01-01

    A clear understanding of how "raw data" is defined, recorded, and retained in the laboratory record is essential to the chemist employed in the laboratory compliant with the Good Laboratory Practices regulations. This article is intended to provide an understanding by drawing upon examples taken from the modern pharmaceutical analysis…

  11. Distance Learning. Leonardo da Vinci Series: Good Practices.

    Science.gov (United States)

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This brochure, part of a series about good practices in vocational training in the European Union, describes 12 projects that use distance learning to promote lifelong learning in adults. The projects and their countries of origin are as follows: (1) 3D Project, training in the use of IT tools for 3D simulation and animation and practical…

  12. A Global Overview of NORM Residue Remediation and Good Practice

    International Nuclear Information System (INIS)

    The issues of management and disposal of NORM residues have been a source of concern for many years in almost every country of the world. However, not all NORM industries have the same ideas when it comes to managing residues and their remediation. The volumes and types of materials vary considerably and so good practice is a situation specific activity, although the basic rules may be similar and the safety standards applied are the same. The phosphate industry has long been a major player in the issue of best practice management and disposal of NORM residues, but it is not always appreciated how the scale of the problems can vary. Similarly, with uranium production, not all the NORM residue issues are on the massive scale that is usually associated with mining operations. Also the oil and gas industries have been managing NORM residues for a long time but good practice is also a dynamic concept and another issue is to determine what is considered to be leading practice nowadays. It should also be pointed out that several other industries may be associated with NORM residues apart from these well known examples. The paper looks at a selected number of international sites and situations to show the variation of size and scope of problems both within and between industries and how good practice is developing in the areas of management, disposal and remediation of NORM residues at the affected sites. (author)

  13. Management Documentation: Indicators & Good Practice at Cultural Heritage Places

    Science.gov (United States)

    Eppich, R.; Garcia Grinda, J. L.

    2015-08-01

    Documentation for cultural heritage places usually refers to describing the physical attributes, surrounding context, condition or environment; most of the time with images, graphics, maps or digital 3D models in their various forms with supporting textural information. Just as important as this type of information is the documentation of managerial attributes. How do managers of cultural heritage places collect information related to financial or economic well-being? How are data collected over time measured, and what are significant indicators for improvement? What quality of indicator is good enough? Good management of cultural heritage places is essential for conservation longevity, preservation of values and enjoyment by the public. But how is management documented? The paper will describe the research methodology, selection and description of attributes or indicators related to good management practice. It will describe the criteria for indicator selection and why they are important, how and when they are collected, by whom, and the difficulties in obtaining this information. As importantly it will describe how this type of documentation directly contributes to improving conservation practice. Good practice summaries will be presented that highlight this type of documentation including Pamplona and Ávila, Spain and Valletta, Malta. Conclusions are drawn with preliminary recommendations for improvement of this important aspect of documentation. Documentation of this nature is not typical and presents a unique challenge to collect, measure and communicate easily. However, it is an essential category that is often ignored yet absolutely essential in order to conserve cultural heritage places.

  14. Clinical audit: Development of the criteria of good practices.

    Science.gov (United States)

    Soimakallio, S; Alanen, A; Järvinen, H; Ahonen, A; Ceder, K; Lyyra-Laitinen, T; Paunio, M; Sinervo, T; Wigren, T

    2011-09-01

    Clinical audit is a systematic review of the procedures in order to improve the quality and the outcome of patient care, whereby the procedures are examined against agreed standards for good medical RADIOLOGICAL procedures. The criteria of good procedures (i.e. the good practice) are thus the cornerstones for development of clinical audits: these should be the basis of assessments regardless of the type of the audit--external, internal, comprehensive or partial. A lot of criteria for good practices are available through the recommendations and publications by international and national professional societies and other relevant organisations. For practical use in clinical audits, the criteria need to be compiled, sorted out and agreed on for the particular aims of an audit (comprehensive or partial, external or internal). The national professional and scientific societies can provide valuable contribution to this development. For examination--or treatment-specific criteria--preliminary consensus needs to be obtained with the help of clinical experts, while clinical audits can be useful as a benchmarking tool to improve the criteria. PMID:21979432

  15. Clinical audit: Development of the criteria of good practices

    International Nuclear Information System (INIS)

    Clinical audit is a systematic review of the procedures in order to improve the quality and the outcome of patient care, whereby the procedures are examined against agreed standards for good medical Radiological procedures. The criteria of good procedures (i.e. the good practice) are thus the cornerstones for development of clinical audits: these should be the basis of assessments regardless of the type of the audit-external, internal, comprehensive or partial. A lot of criteria for good practices are available through the recommendations and publications by international and national professional societies and other relevant organisations. For practical use in clinical audits, the criteria need to be compiled, sorted out and agreed on for the particular aims of an audit (comprehensive or partial, external or internal). The national professional and scientific societies can provide valuable contribution to this development. For examination-or treatment-specific criteria- preliminary consensus needs to be obtained with the help of clinical experts, while clinical audits can be useful as a benchmarking tool to improve the criteria. (authors)

  16. The good laboratory practice and good clinical practice requirements for the production of radiopharmaceuticals in clinical research

    NARCIS (Netherlands)

    De Vos, FJ; De Decker, M; Dierckx, RA

    2005-01-01

    Radiopharmaceuticals account for more than 95% of the group of sterile pharmaceutical products and should therefore be handled and produced with care. Since the introduction of the European directive, all pharmaceuticals used in clinical studies must be prepared under good manufacturing practice (GM

  17. Health physics manual of good practices for accelerator facilities

    International Nuclear Information System (INIS)

    It is hoped that this manual will serve both as a teaching aid as well as a useful adjunct for program development. In the context of application, this manual addresses good practices that should be observed by management, staff, and designers since the achievement of a good radiation program indeed involves a combined effort. Ultimately, radiation safety and good work practices become the personal responsibility of the individual. The practices presented in this manual are not to be construed as mandatory rather they are to be used as appropriate for the specific case in the interest of radiation safety. As experience is accrued and new data obtained in the application of this document, ONS will update the guidance to assure that at any given time the guidance reflects optimum performance consistent with current technology and practice.The intent of this guide therefore is to: define common health physics problems at accelerators; recommend suitable methods of identifying, evaluating, and managing accelerator health physics problems; set out the established safety practices at DOE accelerators that have been arrived at by consensus and, where consensus has not yet been reached, give examples of safe practices; introduce the technical literature in the accelerator health physics field; and supplement the regulatory documents listed in Appendix D. Many accelerator health physics problems are no different than those at other kinds of facilities, e.g., ALARA philosophy, instrument calibration, etc. These problems are touched on very lightly or not at all. Similarly, this document does not cover other hazards such as electrical shock, toxic materials, etc. This does not in any way imply that these problems are not serious. 160 refs

  18. A model for reflection for good clinical practice.

    Science.gov (United States)

    Balla, John I; Heneghan, Carl; Glasziou, Paul; Thompson, Matthew; Balla, Margaret E

    2009-12-01

    Rationale and aim The rapidly changing knowledge base of clinical practice highlights the need to keep abreast of knowledge changes that are most relevant for the practitioner. We aimed to develop a model for reflection on clinical practice that identified the key elements of medical knowledge needed for good medical practice. Method The dual theory of cognition, an integration of intuitive and analytic processes, provided the framework for the study. The design looked at the congruence between the clinical thinking process and the dual theory. A one-year study was conducted in general practice clinics in Oxfordshire, UK. Thirty-five general practitioners participated in 20-minute interviews to discuss how they worked through recently seen clinical cases. Over a one-year period 72 cases were recorded from 35 interviews. These were categorized according to emerging themes, which were manually coded and substantiated with verbatim quotations. Results There was a close fit between the dual theory and participants' clinical thinking processes. This included instant problem framing, consistent with automatic intuitive thinking, focusing on the risk and urgency of the case. Salient features accounting for these choices were recognizable. There was a second reflective phase, leading to the review of initial judgements. Conclusions The proposed model highlights the critical steps in decision making. This allows regular recalibration of knowledge that is most critical at each of these steps. In line with good practice, the model also links the crucial knowledge used in decision making, to value judgments made in relation to the patient. PMID:20367693

  19. [Good practice for medical surveillance by occupational physicians].

    Science.gov (United States)

    Roscelli, F; Frigeri, G; Quercia, A; De Rosa, A

    2006-01-01

    Society--employers, workers, trade unions, public--demands the highest standards of professional competence and ethical conduct from occupational physicians. However, defining what exactly constitutes good medical practice and acceptable standards of professional competence and conduct is not so easily done. Good practice in occupational medicine should be aimed not only at improving the effectiveness of preventive action in the strict sense, but also at constantly adopting rigorous methodologies based on evidence and procedures breaking loose from rigid formats, which must be as uniform as possible throughout the country. It's essential, therefore, to develop consensus documents on workers' health surveillance, meeting with approval of occupational health physicians both operating in a free market context or within the framework of public sector health service. PMID:17144422

  20. EDUCATIONAL POLICIES AND GOOD PRACTICES WITH ICT IN ANDALUSIA REGION

    OpenAIRE

    Juan de Pablos Pons; Pilar Colás Bravo; Patricia Villaciervos Moreno

    2010-01-01

    This contribution is linked to a research project entitled "Education policies and their effects on regional educational innovation in the use of ICT in schools", which has been developed under the National Program Research and Development 2004-2007. The work is focused on discourse analysis about incorporating Andalusian ICT in the educational system. The study allows to understand the concepts involved in the same relation to good practice with ICT education with ICT innovation and ICT use,...

  1. Codes of Good Agricultural Practices for Crop Production in Poland

    OpenAIRE

    Mariusz Fotyma; Irena Duer

    1997-01-01

    The economic and social background of Polish agriculture provides the basis for this discussion of Good Agricultural Practices (GAP). A primary goal of Polish agricultural policy is securing food self-sufficiency for the nation. Accomplishing this goal will require both an intensification of agricultural production in some areas and a concern for environmental protection. Numerous tables and figures illustrate land utilization, soil composition, farm size, and other features of Polish agricul...

  2. Good practices for improved nuclear power plant performance

    International Nuclear Information System (INIS)

    This report provides an overview of operational principles, practice and improvements which have contributed to good performance of eight selected world nuclear power stations. The IAEA Power Reactor Information System (PRIS) was used to identify a population of good performers. It is recognized that there are many other good performing nuclear power stations not included in this report. Specific criteria described in the introduction were used in selecting these eight stations. The information contained in this report was obtained by the staff from IAEA, Division of Nuclear Power. This was accomplished by visits to the stations and visits to a number of utility support groups and three independent organizations which provide support to more than one utility. The information in this report is intended as an aid for operating organizations to identify possible improvement initiatives to enhance plant performance. Figs and tabs

  3. VALUE-ADDED OF GOOD PRACTICES WITH ICT IN SCHOOLS

    Directory of Open Access Journals (Sweden)

    Teresa González Ramírez

    2010-02-01

    Full Text Available This article provides a theoretical and methodological framework in which to place the impact or Value Added of the Best Practices with ICT in schools. To do so, starting from a description of policies of integration of IT and Communication Technologies (ICTs in our country, and more specifically in the autonomous Andalusian community. Following are the main methodological approaches that guide the assessment of current education policies and, by extension, the integration of ICT policies. Policy analysis reflected in the concept of Good Practices as a way to evaluate the policies of integration of ICT in schools within the scope of effectiveness of schools and more specifically within the value-added models in education. Finally, we note that the methodological guidance in our work takes on the concept of added value, providing a list of indicators that can be used for the assessment of ICT policy based on the evaluation of schools and the development of teaching practices.

  4. Using Provenance to support Good Laboratory Practice in Grid Environments

    CERN Document Server

    Ney, Miriam; Schreiber, Andreas

    2011-01-01

    Conducting experiments and documenting results is daily business of scientists. Good and traceable documentation enables other scientists to confirm procedures and results for increased credibility. Documentation and scientific conduct are regulated and termed as "good laboratory practice." Laboratory notebooks are used to record each step in conducting an experiment and processing data. Originally, these notebooks were paper based. Due to computerised research systems, acquired data became more elaborate, thus increasing the need for electronic notebooks with data storage, computational features and reliable electronic documentation. As a new approach to this, a scientific data management system (DataFinder) is enhanced with features for traceable documentation. Provenance recording is used to meet requirements of traceability, and this information can later be queried for further analysis. DataFinder has further important features for scientific documentation: It employs a heterogeneous and distributed data...

  5. Guide to good practices for on-the-job training

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    Training programs at DOE facilities should prepare personnel to safely and efficiently operate and maintain the facilities in accordance with DOE requirements. This guide presents good practices for a systematic approach to on-the-job training (OJT) and OJT programs and should be used in conjunction with DOE Training Program Handbook: A Systematic Approach to Training, and with the DOE Handbook entitled Alternative Systematic Approaches to Training to develop performance-based OJT programs. DOE contractors may also use this guide to modify existing OJT programs that do not meet the systematic approach to training (SAT) objectives.

  6. Good manufacturing practices for medicinal products for human use

    Directory of Open Access Journals (Sweden)

    Bruno G Gouveia

    2015-01-01

    Full Text Available At international and national levels, there are public and private organizations, institutions and regulatory authorities, who work and cooperate between them and with Pharmaceutical Industry, in order to achieve a consensus of the guidelines and laws of the manufacturing of medicinal products for human use. This article includes an explanation of how operate and cooperate these participants, between them and expose the current regulations, following the line of European Community/European Economic Area, referencing, wherever appropriate, the practiced guidelines, outside of regulatory action of space mentioned. In this way, it is intended to achieve quality, security and effectiveness exceptional levels in the manufacturing of health products. Good Manufacturing Practice aim the promotion of the human health and consequently, to the improvement of quality of life. For achieve the proposed objectives, it is necessary to ensure the applicability of the presented concepts and show the benefits arising from this applicability.

  7. Good manufacturing practices for medicinal products for human use.

    Science.gov (United States)

    Gouveia, Bruno G; Rijo, Patrícia; Gonçalo, Tânia S; Reis, Catarina P

    2015-01-01

    At international and national levels, there are public and private organizations, institutions and regulatory authorities, who work and cooperate between them and with Pharmaceutical Industry, in order to achieve a consensus of the guidelines and laws of the manufacturing of medicinal products for human use. This article includes an explanation of how operate and cooperate these participants, between them and expose the current regulations, following the line of European Community/European Economic Area, referencing, wherever appropriate, the practiced guidelines, outside of regulatory action of space mentioned. In this way, it is intended to achieve quality, security and effectiveness exceptional levels in the manufacturing of health products. Good Manufacturing Practice aim the promotion of the human health and consequently, to the improvement of quality of life. For achieve the proposed objectives, it is necessary to ensure the applicability of the presented concepts and show the benefits arising from this applicability.

  8. Identifying critical factors for implementing good agricultural practice

    Directory of Open Access Journals (Sweden)

    Nelson Gutiérrez Guzmán

    2010-05-01

    Full Text Available This paper deals with identifying the critical factors (CFs involved in implementing a good agricultural practice (GAP programme for coffee and fruit farmers in the Huila department of Colombia. An exploratory factor analysis using principal component analy- sis (PCA factorisation was used. Data matrixes were constructed from the results of applying two defined-structure assessment tools to the populations being studied: Starbucks’ coffee and farmer equity (CAFE practices for small-scale coffee growers and coffee-producers and the EUREPGAP V2.1 Oct.2004 / checklist for fruit and vegetables, as applied to fruit-producers. This inves- tigation led to identifying 6 CFs which must be considered when implementing a GAP programme: infrastructure, established production activities, preparing and maintaining records, environmental awareness, workers’ welfare and safety and quality con- trol.

  9. Guide to good practices for operations organization and administration

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    This Guide to Good Practices is written to enhance understanding of, and provide direction for, Operations Organization and Administration, Chapter I of Department of Energy (DOE) Order 5480.19, Conduct of Operations Requirements for DOE Facilities. The practices in this guide should be considered when planning or reviewing operations organization and administration programs. Contractors are advised to adopt procedures that meet the intent of DOE Order 5480.19. This standard should be used in conjunction with principles of the Integrated Safety Management System as incorporated in DOE G 450.4-1, Integrated Safety Management System Guide. Operations Organization and Administration is an element of an effective Conduct of Operations program. The complexity and array of activities performed in DOE facilities dictate the necessity for well-defined standards and requirements for safe and efficient operations.

  10. Good manufacturing practices for medicinal products for human use.

    Science.gov (United States)

    Gouveia, Bruno G; Rijo, Patrícia; Gonçalo, Tânia S; Reis, Catarina P

    2015-01-01

    At international and national levels, there are public and private organizations, institutions and regulatory authorities, who work and cooperate between them and with Pharmaceutical Industry, in order to achieve a consensus of the guidelines and laws of the manufacturing of medicinal products for human use. This article includes an explanation of how operate and cooperate these participants, between them and expose the current regulations, following the line of European Community/European Economic Area, referencing, wherever appropriate, the practiced guidelines, outside of regulatory action of space mentioned. In this way, it is intended to achieve quality, security and effectiveness exceptional levels in the manufacturing of health products. Good Manufacturing Practice aim the promotion of the human health and consequently, to the improvement of quality of life. For achieve the proposed objectives, it is necessary to ensure the applicability of the presented concepts and show the benefits arising from this applicability. PMID:25883511

  11. Analysis of good practice of Public Health Emergency Operations Centers

    Institute of Scientific and Technical Information of China (English)

    Min Xu; Shi-Xue Li

    2015-01-01

    Objective:To study the public health Emergency Operations Centers (EOCs)in the US, the European Union, the UK and Australia, and summarize the good practice for the improvement of National Health Emergency Response Command Center in Chinese National Health and Family Planning Commission.Methods:Literature review was conducted to explore the EOCs of selected countries.Results:The study focused on EOC function, organizational structure, human resources and information management. The selected EOCs had the basic EOC functions of coordinating and commanding as well as the public health related functions such as monitoring the situation, risk assessment, and epidemiological briefings. The organizational structures of the EOCs were standardized, scalable and flexible. Incident Command System was the widely applied organizational structure with a strong preference. The EOCs were managed by a unit of emergency management during routine time and surge staff were engaged upon emergencies. The selected EOCs had clear information management framework including information collection, assessment and dissemination.Conclusions:The performance of National Health Emergency Response Command Center can be improved by learning from the good practice of the selected EOCs, including setting clear functions, standardizing the organizational structure, enhancing the human resource capacity and strengthening information management.

  12. Analysis of good practice of Public Health Emergency Operations Centers

    Institute of Scientific and Technical Information of China (English)

    Min; Xu; Shi-Xue; Li

    2015-01-01

    Objective: To study the public health Emergency Operations Centers(EOCs)in the US, the European Union, the UK and Australia, and summarize the good practice for the improvement of National Health Emergency Response Command Center in Chinese National Health and Family Planning Commission. Methods: Literature review was conducted to explore the EOCs of selected countries. Results: The study focused on EOC function, organizational structure, human resources and information management. The selected EOCs had the basic EOC functions of coordinating and commanding as well as the public health related functions such as monitoring the situation, risk assessment, and epidemiological briefings. The organizational structures of the EOCs were standardized, scalable and flexible. Incident Command System was the widely applied organizational structure with a strong preference. The EOCs were managed by a unit of emergency management during routine time and surge staff were engaged upon emergencies. The selected EOCs had clear information management framework including information collection, assessment and dissemination. Conclusions: The performance of National Health Emergency Response Command Center can be improved by learning from the good practice of the selected EOCs, including setting clear functions, standardizing the organizational structure, enhancing the human resource capacity and strengthening information management.

  13. Hygiene and good manufacturing practice in terms of public health

    Directory of Open Access Journals (Sweden)

    Sibel CEVİZCİ

    2009-04-01

    Full Text Available With globalization, presenting service and product which have good quality and conformity with hygienic regulations, have become more important in health, pharmacy and food sectors. That’s why the quality control and documentation systems which are also considerable in terms of public health, were about to change. Today, lots of companies especially in health sector, prefer “Good Manufacturing Practices (GMP”- including a developed quality-hygiene control and documentation method - that they can easily adapt to their operation system. Food industry is the first application area and contains hygiene and quality management systems. In recent years, conscious of prevention of human health started to reflect on every stages of production of goods and services. In conclusion, GMP came into use in different sectors and demanded in international business trade as a reference. The aim of this review is to present some information about importance and concept of GMP to prevent of public health and to examine its use of areas in various sectors.

  14. Validation of good agricultural practices (GAP) on Minnesota vegetable farms.

    Science.gov (United States)

    Hamilton, Karin E; Umber, Jamie; Hultberg, Annalisa; Tong, Cindy; Schermann, Michele; Diez-Gonzalez, Francisco; Bender, Jeff B

    2015-02-01

    The United States Food and Drug Administration and the Department of Agriculture jointly published the "Guide to Minimize Microbial Food Safety Hazards for Fresh Fruits and Vegetables," which is used as a basis for Good Agricultural Practices (GAP) audits. To understand barriers to incorporation of GAP by Minnesota vegetable farmers, a mail survey completed in 2008 was validated with visits to a subset of the farms. This was done to determine the extent to which actual practices matched perceived practices. Two hundred forty-six producers completed the mail survey, and 27 participated in the on-farm survey. Over 75% of the on-farm survey respondents produced vegetables on 10 acres or less and had 10 or fewer employees. Of 14 questions, excellent agreement between on-farm interviews and mail survey responses was observed on two questions, four questions had poor or slight agreement, and eight questions had no agreement. Ninety-two percent of respondents by mail said "they took measures to keep animals and pests out of packing and storage buildings." However, with the on-site visit only 45% met this requirement. Similarly, 81% of respondents by mail said "measures were taken to reduce the risk of wild and/or domestic animals entering into fruit and vegetable growing areas." With direct observation, 70% of farms actually had taken measures to keep animals out of the growing areas. Additional, on-farm assessments were done regarding employee hygiene, training, presence of animals, water sources, and composting practices. This validation study demonstrated the challenge of creating nonleading and concise questions that are not open to broad interpretation from the respondents. If mail surveys are used to assess GAP, they should include open-ended questions and ranking systems to better assess farm practices. To provide the most accurate survey data for educational purposes or GAP audits, on-farm visits are recommended. PMID:25564923

  15. 76 FR 47593 - Guidance for Small Business Entities on Current Good Manufacturing Practice for Positron Emission...

    Science.gov (United States)

    2011-08-05

    ... a guidance for small business entities entitled ``PET Drugs--Current Good Manufacturing Practice... entitled ``PET Drugs--Current Good Manufacturing Practice (CGMP); Small Entity Compliance Guide.'' This... Manufacturing Practice for Positron Emission Tomography Drugs; Availability AGENCY: Food and Drug...

  16. Preparation of intravenous cholesterol tracer using current good manufacturing practices.

    Science.gov (United States)

    Lin, Xiaobo; Ma, Lina; Racette, Susan B; Swaney, William P; Ostlund, Richard E

    2015-12-01

    Studies of human reverse cholesterol transport require intravenous infusion of cholesterol tracers. Because insoluble lipids may pose risk and because it is desirable to have consistent doses of defined composition available over many months, we investigated the manufacture of cholesterol tracer under current good manufacturing practice (CGMP) conditions appropriate for phase 1 investigation. Cholesterol tracer was prepared by sterile admixture of unlabeled cholesterol or cholesterol-d7 in ethanol with 20% Intralipid(®). The resulting material was filtered through a 1.2 micron particulate filter, stored at 4°C, and tested at time 0, 1.5, 3, 6, and 9 months for sterility, pyrogenicity, autoxidation, and particle size and aggregation. The limiting factor for stability was a rise in thiobarbituric acid-reacting substances of 9.6-fold over 9 months (P manufacturing methods can be achieved in the academic setting and need to be considered for critical components of future metabolic studies.

  17. Good manufacturing practices production of mesenchymal stem/stromal cells.

    Science.gov (United States)

    Sensebé, Luc; Bourin, Philippe; Tarte, Karin

    2011-01-01

    Because of their multi/pluripotency and immunosuppressive properties mesenchymal stem/stromal cells (MSCs) are important tools for treating immune disorders and for tissue repair. The increasing use of MSCs has led to production processes that need to be in accordance with Good Manufacturing Practice (GMP). In cellular therapy, safety remains one of the main concerns and refers to donor validation, choice of starting material, processes, and the controls used, not only at the batch release level but also during the development of processes. The culture processes should be reproducible, robust, and efficient. Moreover, they should be adapted to closed systems that are easy to use. Implementing controls during the manufacturing of clinical-grade MSCs is essential. The controls should ensure microbiological safety but also avoid potential side effects linked to genomic instability driving transformation and senescence or decrease of cell functions (immunoregulation, differentiation potential). In this rapidly evolving field, a new approach to controls is needed.

  18. Preparation of intravenous cholesterol tracer using current good manufacturing practices.

    Science.gov (United States)

    Lin, Xiaobo; Ma, Lina; Racette, Susan B; Swaney, William P; Ostlund, Richard E

    2015-12-01

    Studies of human reverse cholesterol transport require intravenous infusion of cholesterol tracers. Because insoluble lipids may pose risk and because it is desirable to have consistent doses of defined composition available over many months, we investigated the manufacture of cholesterol tracer under current good manufacturing practice (CGMP) conditions appropriate for phase 1 investigation. Cholesterol tracer was prepared by sterile admixture of unlabeled cholesterol or cholesterol-d7 in ethanol with 20% Intralipid(®). The resulting material was filtered through a 1.2 micron particulate filter, stored at 4°C, and tested at time 0, 1.5, 3, 6, and 9 months for sterility, pyrogenicity, autoxidation, and particle size and aggregation. The limiting factor for stability was a rise in thiobarbituric acid-reacting substances of 9.6-fold over 9 months (P manufacturing methods can be achieved in the academic setting and need to be considered for critical components of future metabolic studies. PMID:26416797

  19. Introducing guidelines for good evaluation practice in health informatics.

    Science.gov (United States)

    Nykänen, Pirkko; Brender, Jytte; Ammenwerth, Elske; Talmon, Jan; de Keizer, Nicolette; Rigby, Michael

    2009-01-01

    Good evaluation practice guidelines have been developed through a consensus making process by a core team and the health informatics community. A set of 60 issues has been identified that is relevant for planning, implementation and execution of an evaluation study in the health informatics domain. These issues cover all phases of an evaluation study: Study exploration, first study design, operationalization of methods, detailed study design, execution and finalization of an evaluation study. Issues of risk management and project control are also addressed in the guidelines. Through application of these guidelines the general validity and generalization of evaluation studies are likely to be increased, since these guidelines aim at avoiding a number of omissions, pitfalls and risks. PMID:19745455

  20. An overview of European good practices in public procurement

    Directory of Open Access Journals (Sweden)

    Ada POPESCU

    2016-06-01

    Full Text Available Public procurement has always been a major source of corruption in Europe, as acknowledged by national and European officials, by NGOs and by representatives of civil society. Too often, public procurement serves the personal interests of corrupt officials rather than the best interest of the community. During the last decade, anti-corruption efforts have increasingly focused on public procurement corruption. Most European countries, including European Union members, have tried to eliminate public procurement corruption by implementing new legal rules to ensure compliance with public procurement standards and by prosecuting offenders. After surveying a variety of good practices for eliminating corruption in public procurement in Europe, this paper concludes that the new rules have produced mixed results, with the most unfavourable outcomes occurring in Central and Eastern European countries where public procurement corruption is more virulent than elsewhere in Europe.

  1. Good Practice Guide Waste Minimization/Pollution Prevention

    Energy Technology Data Exchange (ETDEWEB)

    J Dorsey

    1999-10-14

    This Good Practice Guide provides tools, information, and examples for promoting the implementation of pollution prevention during the design phases of U.S. Department of Energy (DOE) projects. It is one of several Guides for implementing DOE Order 430.1, Life-cycle Asset Management. DOE Order 430.1 provides requirements for DOE, in partnership with its contractors, to plan, acquire, operate, maintain, and dispose of physical assets. The goals of designing for pollution prevention are to minimize raw material consumption, energy consumption, waste generation, health and safety impacts, and ecological degradation over the entire life of the facility (EPA 1993a). Users of this Guide will learn to translate national policy and regulatory requirements for pollution prevention into action at the project level. The Guide was written to be applicable to all DOE projects, regardless of project size or design phase. Users are expected to interpret the Guide for their individual project's circumstances, applying a graded approach so that the effort is consistent with the anticipated waste generation and resource consumption of the physical asset. This Guide employs a combination of pollution prevention opportunity assessment (PPOA) methods and design for environment (DfE) philosophies. The PPOA process was primarily developed for existing products, processes, and facilities. The PPOA process has been modified in this Guide to address the circumstances of the DOE design process as delineated in DOE Order 430.1 and its associated Good Practice Guides. This modified form of the PPOA is termed the Pollution Prevention Design Assessment (P2DA). Information on current nationwide methods and successes in designing for the environment also have been reviewed and are integrated into this guidance.

  2. Do quality indicators for general practice teaching practices predict good outcomes for students?

    Science.gov (United States)

    Bartlett, Maggie; Potts, Jessica; McKinley, Bob

    2016-07-01

    Keele medical students spend 113 days in general practices over our five-year programme. We collect practice data thought to indicate good quality teaching. We explored the relationships between these data and two outcomes for students; Objective Structured Clinical Examination (OSCE) scores and feedback regarding the placements. Though both are surrogate markers of good teaching, they are widely used. We collated practice and outcome data for one academic year. Two separate statistical analyses were carried out: (1) to determine how much of the variation seen in the OSCE scores was due to the effect of the practice and how much to the individual student. (2) to identify practice characteristics with a relationship to student feedback scores. (1) OSCE performance: 268 students in 90 practices: six quality indicators independently influenced the OSCE score, though without linear relationships and not to statistical significance. (2) Student satisfaction: 144 students in 69 practices: student feedback scores are not influenced by practice characteristics. The relationships between the quality indicators we collect for practices and outcomes for students are not clear. It may be that neither the quality indicators nor the outcome measures are reliable enough to inform decisions about practices' suitability for teaching. PMID:27117344

  3. Control of food irradiation facilities and good irradiation practices

    International Nuclear Information System (INIS)

    Expansion of irradiation facilities employing commercial scale processes is evident in several countries. The list compiled by the Food Preservation Section of the Joint FAO/IAEA Division, Vienna (April 1988) showed that 34 counties have approved the use of irradiation process for more than 40 food commodities. In Asia and the Pacific Region, the main commercial application of irradiation process is still the sterilization of medical devices but applications to food processing are on the rise. To ensure the safety of irradiated foods, laws and regulations have to be promulgated to govern the facilities, the operations and the products. In most cases, there may be more than one governmental agency involved in regulatory control. The control activities include licensing/registration of a food irradiation premises as a food processing plant, registration of irradiated food in accordance with prescribed standards and regulating labelling practice as well as regularly conducting a comprehensive inspection of the facilities. The quality control programme must cover all aspects of treatment, handling, and distribution. It is emphasized that, as with all food technologies, effective quality control systems needs to be installed and adequately monitored at critical control points at the irradiation facility. Foods should be handled, stored, and transported according to GMP before, during, and after irradiation. Only foods meeting microbiological criteria and other quality standards should be accepted for irradiation. Besides, good irradiation practice (GIP) is also a fundamental principle of practice required specifically for food irradiation. With this recognition, the International Consultative Group on Food Irradiation (ICGFI) has elaborated a set of eight codes of GIP. The quality control system would also include proper packaging suitable for the product. Additional use of a logo to identify irradiated food should be permitted and may even become recognized as a symbol

  4. Good learning practices in the field of science and technology

    Directory of Open Access Journals (Sweden)

    Beatriz Amante García

    2011-09-01

    Full Text Available The European Higher Education Area (EHEA scenario offers a new framework in which the role of universities can be rethought, regardless of the field of new degrees and postgraduate Studies involved. Therefore, the roles of teachers and students might differ significantly as the student would be obliged to request teacher’s guidance in order to acquire not only knowledge, which could be easily obtained elsewhere (books, internet etc. , but also personal skills and, especially, those related to their future professional career.By the term “Good learning practices” we refer to those activities asociated with professorship itself  ,such as those of facilitating and guiding the student learning process, or rather, those activities which are aimed at the student´s thorough learning of specific  (related to the field of study and generic skills.It is now a common occurrence to describe the students of a given classroom as being little motivated and as having great interest in passing but not in actually learning. This fact is quite concerning, as it suggests that the student sees the university as a mere transaction by which they can obtain a degree, certifying that they are apt for the professional world,  where they consider the “real” learning will take place.A good classroom environment is essential for the generation of teaching-learning processes.  It is precisely because of this that we are able to raise the issue of effective practices among teachers who foster a suitable classroom dynamics facilitating, then, the targeted learning experience.  Within this context, there are some authors who discuss good practices by professors especially concerned on how to perform assessment and feedback to enhance student’s learning activity. Thus,  providing them with a deep and lasting impact. Generally speaking, the activities in question are those which enable the student to execute a learning process that will continue throughout

  5. Guide to good practices for the development of test items

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    While the methodology used in developing test items can vary significantly, to ensure quality examinations, test items should be developed systematically. Test design and development is discussed in the DOE Guide to Good Practices for Design, Development, and Implementation of Examinations. This guide is intended to be a supplement by providing more detailed guidance on the development of specific test items. This guide addresses the development of written examination test items primarily. However, many of the concepts also apply to oral examinations, both in the classroom and on the job. This guide is intended to be used as guidance for the classroom and laboratory instructor or curriculum developer responsible for the construction of individual test items. This document focuses on written test items, but includes information relative to open-reference (open book) examination test items, as well. These test items have been categorized as short-answer, multiple-choice, or essay. Each test item format is described, examples are provided, and a procedure for development is included. The appendices provide examples for writing test items, a test item development form, and examples of various test item formats.

  6. [Interpretation of Guidelines on Good Pharmacovigilance Practices for European Union].

    Science.gov (United States)

    Xie, Yan-Ming; Tian, Feng

    2013-09-01

    Due to the limitations of pre-authorization clinical trials, the safety information obtained from them is relatively limited. Therefore, it is very necessary to carry out pharmacovigilance activities on drugs post-marketing. In order to promote the specific implementation of the new pharmacovigilance regulations, the European medicines agency (EMA) developed the Guideline on Good Pharmacovigilance Practices (GVP), as the new criteria for pharmacovigilance in the European Union (EU). Compared with the previously published, Guidelines on Pharmacovigilance for Medicinal Products for Human Use (2007), the GVP proposed more comprehensive and systematic provisions of pharmacovigilance systems, quality control systems, judgements, pharmacovigilance inspections and audits. In addition, it set more specific and comprehensive requirements on risk management systems, the management and reporting of adverse reactions to medicinal products, periodic safety update reports, post-authorization safety studies, signal management, and so on. Interpreting the basic principles, working mechanisms, key technologies and methods of the GVP provides a useful reference for us to carry out pharmacovigilance (especially regarding safety monitoring of parenterally administered Chinese medicine). PMID:24471312

  7. The online good practice guide on job finding

    DEFF Research Database (Denmark)

    The online good practice guide on job finding offers resources, advice and methods to go about finding a job. The guide is not intended as a read from a to z guideline. In this version, the guide is arranged as a document, with a hyperlink structure. However, you can also view the document as small...... and improve your job seeking strategies • Table of content provides you with a list of all the material in the guide. If you use the Bookmark feature in the Adope reader, you can have a similar interactive Table of Content open at all times, while you browse the document. You can choose to explore...... the material based on your needs and the topics that interest you the most or you can choose to read the topics from the beginning to end. In the text all cross-references are marked with red. These red references are implemented as interactive hyperlinks in the document and clicking them will take you...

  8. 78 FR 12068 - Device Good Manufacturing Practice Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-02-21

    ... HUMAN SERVICES Food and Drug Administration Device Good Manufacturing Practice Advisory Committee... meeting will be open to the public. Name of Committee: Device Good Manufacturing Practice Advisory... effects of extreme weather and natural disasters on medical device manufacturing chain processes...

  9. 75 FR 78715 - Small Entity Compliance Guide: Current Good Manufacturing Practice in Manufacturing, Packaging...

    Science.gov (United States)

    2010-12-16

    ... HUMAN SERVICES Food and Drug Administration Small Entity Compliance Guide: Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements; Availability...) is announcing the availability of a guidance entitled ``Current Good Manufacturing Practice...

  10. Publishing integrity and good practices in editing in biomedicine.

    Science.gov (United States)

    Polenakovic, Momir; Gucev, Zoran

    2014-01-01

    The Macedonian Academy of Sciences and Arts (MASA), held a scientific workshop for journal editors in biomedicine: "Publishing integrity and good practices in editing in biomedicine" on April 25, 2014 in MASA, Skopje. The meeting looked into old problems and new situations in editing and publishing, with emphasis on the situation in developing countries. This global knowledge-based society is founded on the results obtained from scientific research. The data from basic research in developed countries contribute in a quite substantial manner to the newly added economic value. One of the main reasons for underdevelopment in South Eastern Europe (SEE) is certainly a low or non-existent contribution of scientific research in the newly added economic value. This has largely to do with the perception of the political elites which simply lack the insight on the crucial importance of science in development. In the long term this leads to societies in which there are distortions in the understanding of the most basic values. Academic publishing has experienced tremendous growth: so far there are at least 50 million scientific articles. Interestingly, publishing in developing countries has experienced a rate of growth higher than in developed countries. However, this is not the case with the Balkan countries. The meeting looked at some old and some newly emerging problems in editing and publishing. First, the high cost for universities and researchers to purchase journals adversely affects both publishing and editing. In developing countries the high cost of purchasing scientific literature is an almost insurmountable problem in spite of the fact that some publishing companies offer discounted fees. Open access journals in South Eastern European (SEE) countries are hardly achievable as this also incurs costs that have to be covered in some way or other. The peer review process has the fundamental difficulty that reviewers are in the situation of a Procrustean bed, tending to

  11. Publishing integrity and good practices in editing in biomedicine.

    Science.gov (United States)

    Polenakovic, Momir; Gucev, Zoran

    2014-01-01

    The Macedonian Academy of Sciences and Arts (MASA), held a scientific workshop for journal editors in biomedicine: "Publishing integrity and good practices in editing in biomedicine" on April 25, 2014 in MASA, Skopje. The meeting looked into old problems and new situations in editing and publishing, with emphasis on the situation in developing countries. This global knowledge-based society is founded on the results obtained from scientific research. The data from basic research in developed countries contribute in a quite substantial manner to the newly added economic value. One of the main reasons for underdevelopment in South Eastern Europe (SEE) is certainly a low or non-existent contribution of scientific research in the newly added economic value. This has largely to do with the perception of the political elites which simply lack the insight on the crucial importance of science in development. In the long term this leads to societies in which there are distortions in the understanding of the most basic values. Academic publishing has experienced tremendous growth: so far there are at least 50 million scientific articles. Interestingly, publishing in developing countries has experienced a rate of growth higher than in developed countries. However, this is not the case with the Balkan countries. The meeting looked at some old and some newly emerging problems in editing and publishing. First, the high cost for universities and researchers to purchase journals adversely affects both publishing and editing. In developing countries the high cost of purchasing scientific literature is an almost insurmountable problem in spite of the fact that some publishing companies offer discounted fees. Open access journals in South Eastern European (SEE) countries are hardly achievable as this also incurs costs that have to be covered in some way or other. The peer review process has the fundamental difficulty that reviewers are in the situation of a Procrustean bed, tending to

  12. Beryllium facilities in India

    International Nuclear Information System (INIS)

    Due to its unique combination of physical, mechanical, thermal and nuclear properties, beryllium is indispensable for many applications in the fields of nuclear and space sciences. Beryllia and copper beryllium alloys have also found extensive applications in the electrical and electronic industries. Beryllium facilities at Bhabha Atomic Research Centre (BARC) have been set up to meet indigenous requirements for these materials. Besides developing beryllium technology, the project team has also designed and developed a number of special purpose equipment. (Author)

  13. Fluorimetric method for determination of Beryllium

    International Nuclear Information System (INIS)

    The old fluorimetric method for the determination of Beryllium, based essentially on the fluorescence of the Beryllium-Morine complex in a strongly alkaline solution, is still competitive and stands the comparison with more modern methods or at least three reasons: in the presence of solid or gaseous samples (powders), the times necessary to finalize an analytic determination are comparable since the stage of the process which lasts the longest is the mineralization of the solid particles containing Beryllium, the cost of a good fluorimeter is by far Inferior to the cost, e. g., of an Emission Spectrophotometer provided with ICP torch and magnets for exploiting the Zeeman effect and of an Atomic absorption Spectrophotometer provided with Graphite furnace; it is possible to determine, fluorimetrically, rather small Beryllium levels (about 30 ng of Beryllium/sample), this potentiality is more than sufficient to guarantee the respect of all the work safety and hygiene rules now in force. The study which is the subject of this publication is designed to the analysis procedure which allows one to reach good results in the determination of Beryllium, chiefly through the control and measurement of the interference effect due to the presence of some metals which might accompany the environmental samples of workshops and laboratories where Beryllium is handled, either at the pure state or in its alloys. The results obtained satisfactorily point out the merits and limits of this analytic procedure

  14. 78 FR 4307 - Current Good Manufacturing Practice Requirements for Combination Products

    Science.gov (United States)

    2013-01-22

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 4 Current Good Manufacturing Practice... good manufacturing practice requirements apply to my combination product? (Sec. 4.3) E. How can I comply with these current good manufacturing practice requirements for a co-packaged or...

  15. 21 CFR 212.2 - What is current good manufacturing practice for PET drugs?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false What is current good manufacturing practice for... HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR POSITRON EMISSION TOMOGRAPHY DRUGS (Eff. 12-12-2011) General Provisions § 212.2 What is current good manufacturing practice...

  16. 21 CFR 210.1 - Status of current good manufacturing practice regulations.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Status of current good manufacturing practice... SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PROCESSING, PACKING, OR HOLDING OF DRUGS; GENERAL § 210.1 Status of current good manufacturing practice...

  17. ORIGINAL ARTICLE: Identification of Practical Pharmacology Skills Useful for Good Clinical Practice

    Directory of Open Access Journals (Sweden)

    V. Shilpa, R. Divya

    2012-07-01

    Full Text Available Background: Awareness about animal ethics is increasing everywhere. This increased awareness coupled with strict regulations discouraging the use of animals for routine experiments have tied the hands of many pharmacologists. They are now forced to develop alternative experiments without using animals. At present, there is acute need to come out with more innovative and useful practical exercises for pharmacology practical sessions. In this background, the present study was undertaken to develop the much-needed alternative experiments. Aims and Objective: To identify new pharmacological practical skills useful for good clinical practice. Material and Methods: A pre-tested questionnaire was administered to 110 doctors of different categories like house surgeons, postgraduate students, assistant professors and professors who are working in a tertiary care hospital. They were asked to give their suggestions regarding new pharmacology practical skills useful for good clinical practice. Statistical analysis: Responses of the participants to the questions asked were tabulated and analyzed. Suggestions given by them were listed out and studied. Results: Use of emergency drugs, dosage calculation, drugs used in pregnancy, case discussions and prescription writing exercises received a lot of support from the participants. Research methodology, cost calculation, animal experiments and interpretation of data of animal experiments did not receive support from the participants. Suggestions given by the participants regarding useful pharmacological skills belonged to the areas like therapeutics, safe use of drugs, recent advances, analysis of information given by the medical representatives and analyzing articles in journals for knowing the efficacy of drugs. Conclusion: Exercises relevant to the clinical practice, as identified in this study, can be introduced as practical pharmacology exercises. Steps are to be taken to highlight the importance of research

  18. Addressing the Challenge of Diversity in the Graduate Ranks: Good Practices Yield Good Outcomes

    Science.gov (United States)

    Thompson, Nancy L.; Campbell, Andrew G.

    2013-01-01

    In this paper, we examine the impact of implementing three systemic practices on the diversity and institutional culture in biomedical and public health PhD training at Brown University. We hypothesized that these practices, designed as part of the National Institutes of Health-funded Initiative to Maximize Student Development (IMSD) program in…

  19. Good practices in audiovisual diversity. Hype or hope?

    OpenAIRE

    García Leiva, María Trinidad; Segovia, Ana I.

    2014-01-01

    Research conducted on the audiovisual industry within the context of the Convention on the Protection and Promotion of the Diversity of Cultural Expressions (UNESCO, 2005) lends weight to the idea that exclusively applying market logic to the field of culture poses a threat to its diversity. It is therefore necessary to identify and foster practices to implement from the public sphere. The question, then, is how to define such practices. The Convention uses the term 'best practice' within a s...

  20. 75 FR 80011 - Good Laboratory Practice for Nonclinical Laboratory Studies

    Science.gov (United States)

    2010-12-21

    ..., 1978 (43 FR 60013). As stated in its scope (Sec. 58.1), this regulation prescribes good laboratory... CONTACT: C. T. Viswanathan, Center for Drug Evaluation and Research, Food and Drug Administration,...

  1. Chronic Beryllium Disease Prevention Program Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S

    2012-03-29

    This document describes how Lawrence Livermore National Laboratory (LLNL) meets the requirements and management practices of federal regulation 10 CFR 850, 'Chronic Beryllium Disease Prevention Program (CBDPP).' This revision of the LLNL CBDPP incorporates clarification and editorial changes based on lessons learned from employee discussions, observations and reviews of Department of Energy (DOE) Complex and commercial industry beryllium (Be) safety programs. The information is used to strengthen beryllium safety practices at LLNL, particularly in the areas of: (1) Management of small parts and components; and (2) Communication of program status to employees. Future changes to LLNL beryllium activities and on-going operating experience will be incorporated into the program as described in Section S, 'Performance Feedback.'

  2. Good practices in collecting umbilical cord and placental blood 1

    Science.gov (United States)

    Lopes, Lauren Auer; Bernardino, Elizabeth; Crozeta, Karla; Guimarães, Paulo Ricardo Bittencourt

    2016-01-01

    Abstract Objective: to identify the factors related to the quality of umbilical cord and placental blood specimens, and define best practices for their collection in a government bank of umbilical cord and placental blood. Method: this was a descriptive study, quantitative approach, performed at a government umbilical cord and placental blood bank, in two steps: 1) verification of the obstetric, neonatal and operational factors, using a specific tool for gathering data as non-participant observers; 2) definition of best practices by grouping non-conformities observed before, during and after blood collection. The data was analyzed using descriptive statistics and the following statistical software: Statistica(r) and R(r). Results: while there was a correlation with obstetrical and neonatal factors, there was a larger correlation with operational factors, resulting in the need to adjust the professional practices of the nursing staff and obstetrical team involved in collecting this type of blood. Based on these non-conformities we defined best practices for nurses before, during and after blood collection. Conclusion: the best practices defined in this study are an important management tool for the work of nurses in obtaining blood specimens of high cell quality. PMID:27556876

  3. Educating Global Citizens: A Good "Idea" or an Organisational Practice?

    Science.gov (United States)

    Lilley, Kathleen; Barker, Michelle; Harris, Neil

    2015-01-01

    Higher education emphasises training and skills for employment, yet while the "idea" of educating global citizens appears in university discourse, there is limited evidence demonstrating how the "idea" of the global citizen translates into practice. Recent research emphasises a desire for graduates to be local and global…

  4. Global Good Practice in Incubation Policy Development and Implementation

    OpenAIRE

    World Bank

    2010-01-01

    This paper was based on a desk review of the literature relating to best practice in public policy supporting business incubation, supplemented by four national case studies covering Brazil, Ma-laysia, New Zealand and South Africa. These country studies were prepared through engage-ment of stakeholders, site visits and other sources of primary and secondary information collection. In the c...

  5. An introduction to good practices in cognitive modeling

    NARCIS (Netherlands)

    A. Heathcote; S.D. Brown; E.-J. Wagenmakers

    2015-01-01

    Cognitive modeling can provide important insights into the underlying causes of behavior, but the validity of those insights rests on careful model development and checking. We provide guidelines on five important aspects of the practice of cognitive modeling: parameter recovery, testing selective i

  6. "Meditation is Good for Nothing:" Leisure as a Democratic Practice

    OpenAIRE

    Mathiowetz, DP

    2016-01-01

    Does meditation bring political benefits in the sense of strengthening citizenship or democracy? Taking the Zen phrase“meditation doesn’t work—it’s good for nothing” as my point of departure, and reading Aristotle’s discussion of leisure in relation to citizenship, I argue that meditation can foster significant dimensions of democratic citizenship. This argument focuses particularly on the avowedly anti-instrumental aspect of mindfulness meditation. The connection between meditation and leisu...

  7. How to improve the performance of a good medical practice team: twelve techniques.

    Science.gov (United States)

    Hills, Laura

    2013-01-01

    It is incredibly easy to ignore the medical practice team that is doing a good job. However, when we allow good performers to continue as they are, they probably won't improve. Their performance may even worsen. This is unfortunate because with a little bit of effort and support, good performers can often learn to excel. This article offers 12 techniques medical practice managers can use to bring their team members from good performance to excellent. It describes how to use goal-setting, work assignments, modeling, confidence building, team retreats, rewards, incentives, and reinforcement to ratchet up a good medical practice team's performance. This article also identifies the signs of medical employee mediocrity. It describes why setting higher expectations of your medical practice employees will ultimately improve their performance. Finally, this article suggests 10 practical and affordable strategies that medical practice managers can use to reinforce excellent performance in their good employees. PMID:23866656

  8. How to improve the performance of a good medical practice team: twelve techniques.

    Science.gov (United States)

    Hills, Laura

    2013-01-01

    It is incredibly easy to ignore the medical practice team that is doing a good job. However, when we allow good performers to continue as they are, they probably won't improve. Their performance may even worsen. This is unfortunate because with a little bit of effort and support, good performers can often learn to excel. This article offers 12 techniques medical practice managers can use to bring their team members from good performance to excellent. It describes how to use goal-setting, work assignments, modeling, confidence building, team retreats, rewards, incentives, and reinforcement to ratchet up a good medical practice team's performance. This article also identifies the signs of medical employee mediocrity. It describes why setting higher expectations of your medical practice employees will ultimately improve their performance. Finally, this article suggests 10 practical and affordable strategies that medical practice managers can use to reinforce excellent performance in their good employees.

  9. VALUE-ADDED OF GOOD PRACTICES WITH ICT IN SCHOOLS

    OpenAIRE

    Teresa González Ramírez; Manuel Rodríguez López

    2010-01-01

    This article provides a theoretical and methodological framework in which to place the impact or Value Added of the Best Practices with ICT in schools. To do so, starting from a description of policies of integration of IT and Communication Technologies (ICTs) in our country, and more specifically in the autonomous Andalusian community. Following are the main methodological approaches that guide the assessment of current education policies and, by extension, the integration of ICT policie...

  10. GOOD PRACTICES REGARDING PRESCHOOL AND PRIMARY SCHOOL TEACHERS` INITIAL TRAINING

    OpenAIRE

    Gabriela V. KELEMEN; Fausto PRESUTTI; Norel, Mariana

    2013-01-01

    The training of future preschool and primary school teachers at a high quality level is a main goal of our institution and all our efforts are channelled towards fulfilling it. Being a teacher is a science, a science based on competences acquired while attending well-structured lectures that mingle theoretical knowledge with practical assignments. Students acquire knowledge, abilities and develop field related competences during initial training but three years of study are not enough. The La...

  11. Setting good practices to assess the efficiency of iron fertilizers.

    Science.gov (United States)

    El-Jendoubi, Hamdi; Melgar, Juan Carlos; Alvarez-Fernández, Ana; Sanz, Manuel; Abadía, Anunciación; Abadía, Javier

    2011-05-01

    The most prevalent nutritional disorder in fruit tree crops growing in calcareous soils is Fe deficiency chlorosis. Iron-deficient, chlorotic tree orchards require Fe-fertilization, since chlorosis causes decreases in tree vegetative growth as well as fruit yield and quality losses. When assessing the effectiveness of Fe-fertilizers, it is necessary to use sound practices based in the state-of-the art knowledge on the physiology and biochemistry of Fe deficiency. This review provides an overview on how to carry out the assessment of the efficiency of Fe-fertilizers, discussing common errors found in the literature, outlining adequate procedures and giving real examples of practical studies carried out in our laboratory in the past decade. The review focuses on: i) the design of Fe-fertilization experiments, discussing several issues such as the convenience of using controlled conditions or field experiments, whether fertilizer assessment experiments should mimic usual fertilization practices, as well as aspects regarding product formulations, dosages, control references and number of replicates; ii) the assessment of chlorosis recovery upon Fe-fertilization by monitoring leaf chlorophyll, and iii) the analysis of the plant responses upon Fe-fertilization, discussing the phases of leaf chlorosis recovery and the control of other leaf nutritional parameters.

  12. Promoting good health research practice in low- and middle-income countries

    OpenAIRE

    Mahendradhata, Yodi; Nabieva, Jamila; Ahmad, Riris Andono; Henley, Patricia; Launois, Pascal; Merle, Corrine; Maure, Christine; Horstick, Olaf; Elango, Varalakshmi

    2016-01-01

    Background: Good clinical practice (GCP) guidelines have been the source of improvement in the quality of clinical trials; however, there are limitations to the application of GCP in the conduct of health research beyond industry-sponsored clinical trials. The UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Disease is promoting good practice in all health research involving human through the Good Health Research Practice (GHRP) training program initiative.Obje...

  13. ORGANIZATIONAL GOOD PRACTICES FOR THE INTEGRATION OF THE ICT IN THE EDUCATION SYSTEM OF EXTREMADURA

    OpenAIRE

    Mª José Sosa Díaz; Sara Peligros García; Dionisio Díaz Muriel

    2010-01-01

    The present paper tries to release some organizational Good Practices for the integration of the ICT's carried out by the Education System in Extremadura. For this, in a first moment, a theoretical review about the concept of Good Practices has been done, establishing some indicators which permit us identify Good Practices regarding the application of the ICT within Primary and Secondary schools, and specially pointing out the indicators that refer to organizational aspects in the educati...

  14. Good Practice for Introducing Radiopharmaceuticals for Clinical Use

    International Nuclear Information System (INIS)

    The use of new radiopharmaceuticals can provide extremely valuable information in the evaluation of cancer, as well as heart and brain diseases. Information that often times cannot be obtained by other means. However, there is a perceived need in many Member States for a useful reference to facilitate and expedite the introduction of radiopharmaceuticals already in clinical use in other countries. This publication intends to provide practical support for the introduction of new radiotracers, including recommendations on the necessary steps needed to facilitate and expedite the introduction of radiopharmaceuticals in clinical use, while ensuring that a safe and high quality product is administered to the patient at all times

  15. E-mobility in Europe trends and good practice

    CERN Document Server

    Leal Filho, Walter

    2015-01-01

    Focusing on technical, policy and social/societal practices and innovations for electrified transport for personal, public and freight purposes, this book provides a state-of-the-art overview of developments in e-mobility in Europe and the West Coast of the USA. It serves as a learning base for further implementing and commercially developing this field for the benefit of society, the environment and public health, as well as for economic development and private industry. A fast-growing, interdisciplinary sector, electric mobility links engineering, infrastructure, environment, transport and

  16. Good manufacturing practices (GMP) utilized on human blood irradiation process

    OpenAIRE

    Cláudio Boghi; Dorlivete M. Shitsuka; Marcos Alexandruk; Ricardo Shitsuka; Paulo Roberto Rela

    2008-01-01

    Irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease), a rare but devastating adverse effect of leukocytes present in blood components for immunocompetent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of lymphocytes. The implementation of the GMP will assure that the properly dose in a range of 25Gy to 50Gy will be delivered to the blood in the bag collected in a blood tissue bank. The stud...

  17. A Practical Quantum Mechanism for the Public Goods Game

    CERN Document Server

    Chen, K Y; Beausoleil, R; Chen, Kay-Yut; Hogg, Tad; Beausoleil, Raymond

    2003-01-01

    Quantum generalizations of conventional games broaden the range of available strategies, which can help improve outcomes for the participants. With many players, such quantum games can involve entanglement among many states which is difficult to implement, especially if the states must be communicated over some distance. This paper describes a quantum mechanism for the economically significant $n$-player public goods game that requires only two-particle entanglement and is thus much easier to implement than more general quantum mechanisms. In spite of the large temptation to free ride on the efforts of others in this game, two-particle entanglement is sufficient to give near optimal expected payoff when players use a simple mixed strategy for which no player can benefit by making different choices. This mechanism can also address some heterogeneous preferences among the players.

  18. Distance learning courses in occupational medicine - Methods and good practice

    Directory of Open Access Journals (Sweden)

    Wagner N

    2005-01-01

    Full Text Available The need for training in Occupational Medicine in India is well known. The majority of company doctors cannot leave their work and join a residence program. The question which course delivery mode - residential or blended or distance education - is appropriate to teach working company doctors is therefore an urgent one. ADULT EDUCATION: Adults learners - in contrast to young students - have a lot prior experiences and knowledge which they want to use. They have tight personal schedules and are very practical and goal-oriented. They usually have a fulltime work. Adults need more guides than lecturers. Immediate use, practice by doing and discussion groups are the most powerful tools in teaching. Lecturing seems to be the most ineffective teaching method. Distance education is widely used already in teaching occupational health & safety and occupational medicine (OSH in other countries. Almost 100% of all post-graduate teaching in occupational medicine is done by distance education in the U. K. A "blended" course model seems appropriate for Occupational Medicine teaching. It has contact phases and self-learning phases The Indian Association of Occupational Health could play a leading role in expending high quality teaching in Occupational Medicine. These activities would contribute to the Government′s goals to strengthen Occupational Health in India. This article discusses distance education and online-teaching as one viable way to deliver high quality training in Occupational Medicine to working company doctors in India.

  19. Delivering research data management services fundamentals of good practice

    CERN Document Server

    Jones, Sarah; Whyte, Angus

    2014-01-01

    The research landscape is changing, with key global research funders now requiring institutions to demonstrate how they will preserve and share research data. However, the practice of structured research data management is very new, and the construction of services remains experimental and in need of models and standards of approach. This groundbreaking guide will lead researchers, institutions and policy makers through the processes needed to set up and run effective institutional research data management services. This book will provide a step-by-step explanation of the components for an institutional service - effectively a 'how to guide'. Case studies from the newly emerging service infrastructures in the UK, USA and Australia will draw out the lessons learnt from working (or near to delivery) exemplars. Different approaches are highlighted and compared, for example, a case study of a researcher-focused strategy from Australia contrasted with a national, top-down approach. A chapter on the redeveloped UK ...

  20. Energy efficiency in Europe. Overview of policies and good practices

    International Nuclear Information System (INIS)

    As part of its Presidency of the Club EnR, a network of 24 national energy management agencies in Europe, ADEME drew up a brochure in 2014 on policies and best practices for energy efficiency in the countries of the European Union. An overview of the actions and programmes of 'neighbouring countries' is also given in this brochure. This action is a concrete part of the knowledge-sharing approach that encourages wide dissemination of proven or particularly promising policies. After an introductory chapter on the key figures and general objectives of the EU, the document is structured into 10 consumer industries and supplemented by a chapter on cross-industry measures. The conclusion draws lessons and makes recommendations to improve the results of future actions

  1. Beryllium Desorption from Sediments

    Science.gov (United States)

    Boschi, V.; Willenbring, J. K.

    2015-12-01

    Beryllium isotopes have provided a useful tool in the field of geochronology and geomorphology over the last 25 years. The amount of cosmogenic meteoric 10Be and native 9Be absorbed to soils often scales with the residence time and chemical weathering of sediments in a landscape, respectively. Thus, the concentrations in river sediment may be used to quantify the denudation of specific watersheds. When deposited in ocean sediment, these concentrations are thought to record the history of denudation on Earth over the last ~10 Ma. The use of both isotopes often relies on the premise of beryllium retention to sediment surfaces in order to preserve a landscape's erosion and weathering signature. Changes in setting, en route from the soil to fluvial system to the ocean, can cause beryllium desorption and may preclude some applications of the 10Be/9Be system. Four mechanisms were tested to determine the desorption potential of beryllium including a reduction in pH, an increase in ionic strength and complexation with soluble organic and inorganic species. These processes have the potential to mobilize beryllium into solution. For example, by both reducing the pH and increasing the ionic strength, competition for adsorption sites increases, potentially liberating beryllium from the sediment surface. In addition, organic and inorganic ligands can complex beryllium causing it to become mobilized. To determine which of these alterations influence beryllium desorption and to quantify the effect, we prepared separate solutions of beryllium bound to minerals and organic compounds and measured beryllium concentrations in solution before and after adjusting the pH, ionic strength, and changing inorganic and organic ligand concentrations. We conclude from our observations that overall, beryllium sorbed to organic compounds was more resistant to desorption relative to mineral-associated beryllium. Among the methods tested, a reduction in pH resulted in the greatest amount of

  2. De praeceptis ferendis: good practice in multi-model ensembles

    Directory of Open Access Journals (Sweden)

    I. Kioutsioukis

    2014-06-01

    Full Text Available Ensembles of air quality models have been formally and empirically shown to outperform single models in many cases. Evidence suggests that ensemble error is reduced when the members form a diverse and accurate ensemble. Diversity and accuracy are hence two factors that should be taken care of while designing ensembles in order for them to provide better predictions. There exists a trade-off between diversity and accuracy for which one cannot be gained without expenses of the other. Theoretical aspects like the bias-variance-covariance decomposition and the accuracy-diversity decomposition are linked together and support the importance of creating ensemble that incorporates both the elements. Hence, the common practice of unconditional averaging of models without prior manipulation limits the advantages of ensemble averaging. We demonstrate the importance of ensemble accuracy and diversity through an inter-comparison of ensemble products for which a sound mathematical framework exists, and provide specific recommendations for model selection and weighting for multi model ensembles. To this end we have devised statistical tools that can be used for diagnostic evaluation of ensemble modelling products, complementing existing operational methods.

  3. Implementation of good manufacturing practices (GMP) on human blood irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Boghi, Claudio; Napolitano, Celia M.; Ferreira, Danilo C.; Rela, Paulo Roberto [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mails: cboghi@uol.com.br; cmnapoli@ipen.br; dancarde@ig.com.br; prela@ipen.br; Zarate, Herman S. [Comission Chilena de Energia Nuclear, Santiago (Chile)]. E-mail: hzarate@cchen.cl

    2007-07-01

    The irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease), a rare but devastating adverse effect of leukocytes present in blood components for a immuno-competent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of lymphocytes. The implementation of the GMP will assure that the properly dose in a range of 25 Gy to 50 Gy will be delivered to the blood in the bag collected in a blood tissue bank. The studies to establish the GMP were developed under the guidelines of the standard ISO 11137 - Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. In this work, two dosimetric systems were used for dose mapping during the studies of irradiator qualification, loading pattern, irradiation process validation and auditing. The CaSO{sub 4}: Dy dosimeter presented difficulties concerning to uncertainty on dose measurement, stability, trace ability and calibration system. The PMMA and gafchromic dosimetric systems have shown a better performance and were adopted on establishment of GMP procedures. The irradiation tests have been done using a Gammacell 220 Irradiator. The developed GMP can be adapted for different types of gamma irradiators, allowing to set up a quality assurance program for blood irradiation. (author)

  4. Good manufacturing practices (GMP utilized on human blood irradiation process

    Directory of Open Access Journals (Sweden)

    Cláudio Boghi

    2008-01-01

    Full Text Available Irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease, a rare but devastating adverse effect of leukocytes present in blood components for immunocompetent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of lymphocytes. The implementation of the GMP will assure that the properly dose in a range of 25Gy to 50Gy will be delivered to the blood in the bag collected in a blood tissue bank. The studies to establish the GMP were developed under the guidelines of the standard ISO 11137 - Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. In this work, two dosimetric systems were used for dose mapping during the studies of irradiator qualification, loading pattern, irradiation process validation and auditing. The CaSO4: Dy dosimeter presented difficulties concerning to uncertainty on dose measurement, stability, trace ability and calibration system. The PMMA and gafchromic dosimetric systems have shown a better performance and were adopted on establishment of GMP procedures. The irradiation tests have been done using a Gammacell 220 Irradiator. The developed GMP can be adapted for different types of gamma irradiators, allowing to set up a quality assurance program for blood irradiation.

  5. 40 CFR 79.60 - Good laboratory practices (GLP) standards for inhalation exposure health effects testing.

    Science.gov (United States)

    2010-07-01

    ... Testing Requirements for Registration § 79.60 Good laboratory practices (GLP) standards for inhalation... have immediately available manuals and standard operating procedures relative to the laboratory... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Good laboratory practices...

  6. Implementing Good Practices Programs to Encourage Production of High-Quality, Safer Produce in Mississippi

    Science.gov (United States)

    Mahmoud, Barakat S. M.; Stafne, Eric T.; Coker, Christine H.; Bachman, Gary R.; Bell, Nicole

    2016-01-01

    Fifty-four growers/producers attended four 1-day good agricultural practices (GAP) and good handling practices (GHP) workshops at four locations in Mississippi. Pre- and post workshop survey data indicated that the participants' food safety knowledge increased by 15%. Furthermore, the workshops helped producers develop their own food safety plans.…

  7. Modeling good research practices--overview: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-1.

    Science.gov (United States)

    Caro, J Jaime; Briggs, Andrew H; Siebert, Uwe; Kuntz, Karen M

    2012-01-01

    Models-mathematical frameworks that facilitate estimation of the consequences of health care decisions-have become essential tools for health technology assessment. Evolution of the methods since the first ISPOR modeling task force reported in 2003 has led to a new task force, jointly convened with the Society for Medical Decision Making, and this series of seven papers presents the updated recommendations for best practices in conceptualizing models; implementing state-transition approaches, discrete event simulations, or dynamic transmission models; dealing with uncertainty; and validating and reporting models transparently. This overview introduces the work of the task force, provides all the recommendations, and discusses some quandaries that require further elucidation. The audience for these papers includes those who build models, stakeholders who utilize their results, and, indeed, anyone concerned with the use of models to support decision making. PMID:22990082

  8. Modeling good research practices--overview: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force--1.

    Science.gov (United States)

    Caro, J Jaime; Briggs, Andrew H; Siebert, Uwe; Kuntz, Karen M

    2012-01-01

    Models--mathematical frameworks that facilitate estimation of the consequences of health care decisions--have become essential tools for health technology assessment. Evolution of the methods since the first ISPOR Modeling Task Force reported in 2003 has led to a new Task Force, jointly convened with the Society for Medical Decision Making, and this series of seven articles presents the updated recommendations for best practices in conceptualizing models; implementing state-transition approaches, discrete event simulations, or dynamic transmission models; and dealing with uncertainty and validating and reporting models transparently. This overview article introduces the work of the Task Force, provides all the recommendations, and discusses some quandaries that require further elucidation. The audience for these articles includes those who build models, stakeholders who utilize their results, and, indeed, anyone concerned with the use of models to support decision making. PMID:22999128

  9. 21 CFR 210.2 - Applicability of current good manufacturing practice regulations.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Applicability of current good manufacturing... AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PROCESSING, PACKING, OR HOLDING OF DRUGS; GENERAL § 210.2 Applicability of current good...

  10. Ensuring Compliance of Raw Herbal Materials Stemmed from China with European Good Agricultural and Collection Practice

    Institute of Scientific and Technical Information of China (English)

    ANDRE Philippe; SU Hao-bo; GAO Wen-yuan

    2011-01-01

    A"simplified" European procedure now allows the registration of traditional herbal medicines as medicinal products even without the support of clinical data.This procedure entails the requirement that those products comply with European Good Manufacturing Practice for medicinal products,which in turn implies that the raw herbal materials comply with the European Guidelines for Good Agricultural and Collection Practice.On the basis of a comparison between European Good Agricultural and Collection Practice and China Good Agricultural Practice,as well as direct observation made at sites in China,we issue some recommendations to facilitate good communication between the Chinese producer and European pharmaceutical customer,with a view to ensure full compliance with European expectations.

  11. Importance and globalization status of good manufacturing practice (GMP) requirements for pharmaceutical excipients.

    Science.gov (United States)

    Abdellah, Abubaker; Noordin, Mohamed Ibrahim; Wan Ismail, Wan Azman

    2015-01-01

    Pharmaceutical excipients are no longer inert materials but it is effective and able to improve the characteristics of the products' quality, stability, functionality, safety, solubility and acceptance of patients. It can interact with the active ingredients and alter the medicament characteristics. The globalization of medicines' supply enhances the importance of globalized good manufacturing practice (GMP) requirements for pharmaceutical excipients. This review was intended to assess the globalization status of good manufacturing practice (GMP) requirements for pharmaceutical excipients. The review outcomes demonstrate that there is a lack of accurately defined methods to evaluate and measure excipients' safety. Furthermore good manufacturing practice requirements for excipients are not effectively globalized.

  12. Good Practices In Instructional Process Among Current Educational Programs For Basic Education In Indonesia

    Directory of Open Access Journals (Sweden)

    Laurens Kaluge

    2016-02-01

    Full Text Available Comparing the good practices in the area of teaching learning improvement, several points are raised here. The five programs covering teaching learning improvement component are MBE, CLCC, NTT-PEP, SEQIP, and CTL. Through a survey in seven provinces, data were collected from various bureaucrats, school practitioners, students, and their parents. Within the component of the teaching learning improvement there are several elements which are commonly available among the projects. Those elements are preparation of good teachers, provision and development of resources, and practice teaching learning activities are considered to be good practices.

  13. Beryllium Manufacturing Processes

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, A

    2006-06-30

    This report is one of a number of reports that will be combined into a handbook on beryllium. Each report covers a specific topic. To-date, the following reports have been published: (1) Consolidation and Grades of Beryllium; (2) Mechanical Properties of Beryllium and the Factors Affecting these Properties; (3) Corrosion and Corrosion Protection of Beryllium; (4) Joining of Beryllium; (5) Atomic, Crystal, Elastic, Thermal, Nuclear, and other Properties of Beryllium; and (6) Beryllium Coating (Deposition) Processes and the Influence of Processing Parameters on Properties and Microstructure. The conventional method of using ingot-cast material is unsuitable for manufacturing a beryllium product. Beryllium is a highly reactive metal with a high melting point, making it susceptible to react with mold-wall materials forming beryllium compounds (BeO, etc.) that become entrapped in the solidified metal. In addition, the grain size is excessively large, being 50 to 100 {micro}m in diameter, while grain sizes of 15 {micro}m or less are required to meet acceptable strength and ductility requirements. Attempts at refining the as-cast-grain size have been unsuccessful. Because of the large grain size and limited slip systems, the casting will invariably crack during a hot-working step, which is an important step in the microstructural-refining process. The high reactivity of beryllium together with its high viscosity (even with substantial superheat) also makes it an unsuitable candidate for precision casting. In order to overcome these problems, alternative methods have been developed for the manufacturing of beryllium. The vast majority of these methods involve the use of beryllium powders. The powders are consolidated under pressure in vacuum at an elevated temperature to produce vacuum hot-pressed (VHP) blocks and vacuum hot-isostatic-pressed (HIP) forms and billets. The blocks (typically cylindrical), which are produced over a wide range of sizes (up to 183 cm dia. by 61

  14. Controlling Beryllium Contaminated Material And Equipment For The Building 9201-5 Legacy Material Disposition Project

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, T. D.; Easterling, S. D.

    2010-10-01

    This position paper addresses the management of beryllium contamination on legacy waste. The goal of the beryllium management program is to protect human health and the environment by preventing the release of beryllium through controlling surface contamination. Studies have shown by controlling beryllium surface contamination, potential airborne contamination is reduced or eliminated. Although there are areas in Building 9201-5 that are contaminated with radioactive materials and mercury, only beryllium contamination is addressed in this management plan. The overall goal of this initiative is the compliant packaging and disposal of beryllium waste from the 9201-5 Legacy Material Removal (LMR) Project to ensure that beryllium surface contamination and any potential airborne release of beryllium is controlled to levels as low as practicable in accordance with 10 CFR 850.25.

  15. 77 FR 36277 - Academic Development of a Training Program for Good Laboratory Practices in High Containment...

    Science.gov (United States)

    2012-06-18

    .... Lecture examples would include a GLP Refresher, Good Documentation practices, Internal GLP Audits... conducting studies in BSL-4 laboratories. An entire half-day will be devoted to teaching what is...

  16. Top 10 metrics for life science software good practices [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Haydee Artaza

    2016-08-01

    Full Text Available Metrics for assessing adoption of good development practices are a useful way to ensure that software is sustainable, reusable and functional. Sustainability means that the software used today will be available - and continue to be improved and supported - in the future. We report here an initial set of metrics that measure good practices in software development. This initiative differs from previously developed efforts in being a community-driven grassroots approach where experts from different organisations propose good software practices that have reasonable potential to be adopted by the communities they represent. We not only focus our efforts on understanding and prioritising good practices, we assess their feasibility for implementation and publish them here.

  17. ORGANIZATIONAL GOOD PRACTICES FOR THE INTEGRATION OF THE ICT IN THE EDUCATION SYSTEM OF EXTREMADURA

    Directory of Open Access Journals (Sweden)

    Mª José Sosa Díaz

    2010-02-01

    Full Text Available The present paper tries to release some organizational Good Practices for the integration of the ICT's carried out by the Education System in Extremadura. For this, in a first moment, a theoretical review about the concept of Good Practices has been done, establishing some indicators which permit us identify Good Practices regarding the application of the ICT within Primary and Secondary schools, and specially pointing out the indicators that refer to organizational aspects in the educational establishments and classrooms. Secondly, the politics for the integration of New Technologies conducted by Junta de Extremadura are analyzed, emphasizing the figure of the ICT Coordinator as a quality measure, as well as the technological tools for school management and controlling the classes. Finally, we present the results obtained from several interviews that were made to different members of the school community, all in a broader investigation where diverse case studies of Primary and Secondary schools considered as Good Practices with ICT were effectuated.

  18. 77 FR 49448 - Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice...

    Science.gov (United States)

    2012-08-16

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food and Drug Administration (FDA), Baltimore District Office,...

  19. Postirradiation examination of beryllium pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Gelles, D.S. [Pacific Northwest National Lab., Richland, WA (United States)

    1998-03-01

    Postirradiation examinations of COBRA-1A beryllium pebbles irradiated in the EBR-II fast reactor at neutron fluences which generated 2700--3700 appm helium have been performed. Measurements included density change, optical microscopy, scanning electron microscopy, and transmission electron microscopy. The major change in microstructure is development of unusually shaped helium bubbles forming as highly non-equiaxed thin platelet-like cavities on the basal plane. Measurement of the swelling due to cavity formation was in good agreement with density change measurements.

  20. Beryllium development programme in India

    International Nuclear Information System (INIS)

    India has fairly large deposits of beryl. The requirement of beryllium and copper-beryllium alloys in space and electronic industries has provided the incentive for the setting up of an indigenous base for the development of beryllium process metallurgy. The paper presents the developmental work carried out, in the Metallurgy Division of the Bhabha Atomic Research Centre, on the preparation of beryllium metal and its alloys starting from Indian beryl. A laboratory facility incorporating essential precautionary measures has been set up for the safe handling of beryllium and its compounds. Based on the laboratory investigations a flow-sheet suitable to Indian conditions has been developed. The flow-sheet involves preparation of anhydrous beryllium fluoride from beryl through the silico-fluoride route, magnesiothermic reduction of beryllium fluoride for the production of beryllium metal or its master alloy with copper or aluminium, and fabrication of beryllium metal. (author)

  1. BEST PRACTICES OF GOOD GOVERNANCE - RELATIONSHIP BETWEEN THE PRINCIPLES OF GOVERNANCE AND THE ETHICAL CONDUCT

    OpenAIRE

    Samsuri, Suraya

    2011-01-01

    Good corporate governance and ethical practices are no longer optional but instead has gradually becoming part of the laws. No doubt that ‘Code of Ethics’ is good for refinement of corporate governance, in fact, each country or organization does nurture its own distinctive code of ethics based on the core values of the societies or businesses. However, even with numerous initiatives undertook in instilling and inculcating good values, ethical conduct, integrity and efforts to avoid potential ...

  2. Armenia : Diagnostic Review of Consumer Protection and Financial Literacy, Volume 2. Comparison with Good Practices

    OpenAIRE

    World Bank

    2012-01-01

    The objectives of the diagnostic review of consumer protection and financial literacy for Armenia are: (i) to assess the existing financial consumer protection framework, by reviewing laws, regulations and practices in Armenia compared to international good practices; and (ii) to provide recommendations on ways to improve consumer protection and financial literacy in Armenia. The review pr...

  3. Good Practice Guide: Bringing a Social Capital Approach into the Teaching of Adult Literacy and Numeracy

    Science.gov (United States)

    National Centre for Vocational Education Research (NCVER), 2010

    2010-01-01

    This good practice guide is based on research that looked at how to teach adult literacy and numeracy using a social capital approach. The guide suggests ways vocational education and training (VET) practitioners can adopt a social capital approach to their teaching practice. A social capital approach refers to the process in which networks are…

  4. Knowledge for the good of the individual and society: linking philosophy, disciplinary goals, theory, and practice.

    Science.gov (United States)

    McCurry, Mary K; Revell, Susan M Hunter; Roy, Sr Callista

    2010-01-01

    Nursing as a profession has a social mandate to contribute to the good of society through knowledge-based practice. Knowledge is built upon theories, and theories, together with their philosophical bases and disciplinary goals, are the guiding frameworks for practice. This article explores a philosophical perspective of nursing's social mandate, the disciplinary goals for the good of the individual and society, and one approach for translating knowledge into practice through the use of a middle-range theory. It is anticipated that the integration of the philosophical perspective and model into nursing practice will strengthen the philosophy, disciplinary goal, theory, and practice links and expand knowledge within the discipline. With the focus on humanization, we propose that nursing knowledge for social good will embrace a synthesis of the individual and the common good. This approach converges vital and agency needs described by Hamilton and the primacy of maintaining the heritage of the good within the human species as outlined by Maritain. Further, by embedding knowledge development in a changing social and health care context, nursing focuses on the goals of clinical reasoning and action. McCubbin and Patterson's Double ABCX Model of Family Adaptation was used as an example of a theory that can guide practice at the community and global level. Using the theory-practice link as a foundation, the Double ABCX model provides practising nurses with one approach to meet the needs of individuals and society. The integration of theory into nursing practice provides a guide to achieve nursing's disciplinary goals of promoting health and preventing illness across the globe. When nursing goals are directed at the synthesis of the good of the individual and society, nursing's social and moral mandate may be achieved.

  5. ENVIRONMENTAL RISK ASSESSMENT OF SOME COPPER BASED FUNGICIDES ACCORDING TO THE REQUIREMENTS OF GOOD LABORATORY PRACTICE

    Directory of Open Access Journals (Sweden)

    Marga GRĂDILĂ

    2015-10-01

    Full Text Available The paper presents data demonstrating the functionality of biological systems reconstituted with aquatic organisms developed under Good Laboratory Practice testing facility within Research - Development Institute for Plant Protection Bucharest for environmental risk assessment of four fungicides based on copper, according to Good Laboratory Practice requirements. For risk assessment, according to GLP were made the following steps: Good Laboratory Practice test facility was established, we have ensured adequate space for growth, acclimatization and testing for each test species, it was installed a complex water production instalation needed to perform tests, it was achieved control system for checking environmental conditions and have developed specific operating procedures that have been accredited according to Good Laboratory Practice.The results showed that biological systems model of the Good Laboratory Practice test facility in Research - Development Institute for Plant Protection meet the requirements of Organisation for Economic Co-operation and Development Guidelines regarding GLP, and after testing copper-based fungicides in terms of acute toxicity Cyprinus carpio and to Daphnia magna revealed that three of them (copper oxychloride, copper hydroxide and copper sulphate showed ecological efficiency, ie low toxicity. Metallic copper based fungicides showed a higher toxicity, resulting in fish toxicity symptoms: sleep, sudden immersion, faded, weakness, swimming in spiral, lack of balance, breathing slow and cumbersome, spasms and mortality.

  6. 78 FR 22887 - Guidance for Industry on Non-Penicillin Beta-Lactam Drugs: A Current Good Manufacturing Practices...

    Science.gov (United States)

    2013-04-17

    ... Current Good Manufacturing Practices Framework for Preventing Cross- Contamination; Availability AGENCY... health risks associated with cross-reactivity. Although the existing current good manufacturing practices (CGMP) regulations require separation of manufacturing facilities to avoid cross-contamination, the...

  7. Fluorimetric method for determination of Beryllium; Determinazione fluorimetrica del berillio

    Energy Technology Data Exchange (ETDEWEB)

    Sparacino, N.; Sabbioneda, S. [ENEA, Centro Ricerche Saluggia, Vercelli (Italy). Dip. Energia

    1996-10-01

    The old fluorimetric method for the determination of Beryllium, based essentially on the fluorescence of the Beryllium-Morine complex in a strongly alkaline solution, is still competitive and stands the comparison with more modern methods or at least three reasons: in the presence of solid or gaseous samples (powders), the times necessary to finalize an analytic determination are comparable since the stage of the process which lasts the longest is the mineralization of the solid particles containing Beryllium, the cost of a good fluorimeter is by far Inferior to the cost, e. g., of an Emission Spectrophotometer provided with ICP torch and magnets for exploiting the Zeeman effect and of an Atomic absorption Spectrophotometer provided with Graphite furnace; it is possible to determine, fluorimetrically, rather small Beryllium levels (about 30 ng of Beryllium/sample), this potentiality is more than sufficient to guarantee the respect of all the work safety and hygiene rules now in force. The study which is the subject of this publication is designed to the analysis procedure which allows one to reach good results in the determination of Beryllium, chiefly through the control and measurement of the interference effect due to the presence of some metals which might accompany the environmental samples of workshops and laboratories where Beryllium is handled, either at the pure state or in its alloys. The results obtained satisfactorily point out the merits and limits of this analytic procedure.

  8. From Good Practices to Effective Policies for Preventing Errors in Spreadsheets

    CERN Document Server

    Kulesz, Daniel

    2011-01-01

    Thanks to the enormous flexibility they provide, spreadsheets are considered a priceless blessing by many end-users. Many spreadsheets, however, contain errors which can lead to severe consequences in some cases. To manage these risks, quality managers in companies are often asked to develop appropriate policies for preventing spreadsheet errors. Good policies should specify rules which are based on "known-good" practices. While there are many proposals for such practices in literature written by practitioners and researchers, they are often not consistent with each other. Therefore no general agreement has been reached yet and no science-based "golden rules" have been published. This paper proposes an expert-based, retrospective approach to the identification of good practices for spreadsheets. It is based on an evaluation loop that cross-validates the findings of human domain experts against rules implemented in a semi-automated spreadsheet workbench, taking into account the context in which the spreadsheet...

  9. 78 FR 17142 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-03-20

    ... correcting the January 16, 2013 (78 FR 3646), proposed rule entitled ``Current Good Manufacturing Practice..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based... regulation for current good manufacturing practice in manufacturing, packing, or holding human food...

  10. 78 FR 24691 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-04-26

    ..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based... the proposed rule, ``Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive... rule entitled ``Current Good Manufacturing Practice and Hazard Analysis and Risk-Based...

  11. 78 FR 11611 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-02-19

    ..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based... ``Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for Human Food... rule entitled ``Current Good Manufacturing Practice and Hazard Analysis and Risk-Based...

  12. 78 FR 69604 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-11-20

    ..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based... 3646), entitled ``Current Good Manufacturing Practice and Hazard Analysis and Risk- Based Preventive... rule entitled ``Current Good Manufacturing Practice and Hazard Analysis and Risk-Based...

  13. 78 FR 64735 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-10-29

    ... 16, 225, 500 et al. Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive... Administration 21 CFR Parts 16, 225, 500, 507, and 579 RIN 0910-AG10 Current Good Manufacturing Practice and..., and Cosmetic Act (the FD&C Act) to establish requirements for current good manufacturing practice...

  14. 78 FR 48636 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-08-09

    ..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based... Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for Human Food... period. These two proposals are related to the proposed rule ``Current Good Manufacturing Practice...

  15. Good faith in the lex mercatoria: an analysis of arbitral practice and major western legal systems

    OpenAIRE

    Carvajal-Arenas, Lorena

    2011-01-01

    This thesis is a comprehensive guide to the current interpretation of the principle of good faith in the lex mercatoria. It sets out the full background to this interpretation, exploring the development of good faith in major legal cultures in the Western world and in arbitral practice. Modern lex mercatoria is one of the most conspicuous manifestations of globalization in the field of law. Previous examples of global law are the Roman ius gentium and the medieval law merchant. The pri...

  16. Good practices in virtual leadership – the e-3cs rule (communication, trust and coordination)

    OpenAIRE

    Samartinho, João; Silva, Paulo; Faria, Jorge

    2014-01-01

    Studies conducted under a doctorate programme, aiming at designing a Skills and Good Practices Model in e-leadership, clearly identified, from literature review, eDelphi study and further analysis of the results obtained from an interview Focus Group, a set of items linked to e-Leaders specific skills and good practices required in the process of collaborative learning within virtual teams ( e- Teams): “ 11 – Effective e-leader communication”, “ 5 - e-leader skills to building trust”, “12- Op...

  17. GreyGuide - Guide to Good Practice in Grey Literature: A Community Driven Open Resource Project

    OpenAIRE

    Biagioni, Stefania; Carlesi, Carlo; Schopfel, Joachim; Farace, Dominic J.; Frantzen, Jerry; GreyNet, Grey Literature Network Service

    2014-01-01

    The goal of this project is to develop an open source repository of good practices in the field of grey literature. That which originated in monographic form will now open and expand to include content from the global grey literature community. Such practices will range from the production and processing of grey literature through to its distribution, uses, and preservation. The repository will contain guidelines such as those in handling theses and dissertations, how to write research report...

  18. Multiple Criteria Decision Analysis for Health Care Decision Making--Emerging Good Practices: Report 2 of the ISPOR MCDA Emerging Good Practices Task Force.

    Science.gov (United States)

    Marsh, Kevin; IJzerman, Maarten; Thokala, Praveen; Baltussen, Rob; Boysen, Meindert; Kaló, Zoltán; Lönngren, Thomas; Mussen, Filip; Peacock, Stuart; Watkins, John; Devlin, Nancy

    2016-01-01

    Health care decisions are complex and involve confronting trade-offs between multiple, often conflicting objectives. Using structured, explicit approaches to decisions involving multiple criteria can improve the quality of decision making. A set of techniques, known under the collective heading, multiple criteria decision analysis (MCDA), are useful for this purpose. In 2014, ISPOR established an Emerging Good Practices Task Force. The task force's first report defined MCDA, provided examples of its use in health care, described the key steps, and provided an overview of the principal methods of MCDA. This second task force report provides emerging good-practice guidance on the implementation of MCDA to support health care decisions. The report includes: a checklist to support the design, implementation and review of an MCDA; guidance to support the implementation of the checklist; the order in which the steps should be implemented; illustrates how to incorporate budget constraints into an MCDA; provides an overview of the skills and resources, including available software, required to implement MCDA; and future research directions.

  19. Multiple Criteria Decision Analysis for Health Care Decision Making--Emerging Good Practices: Report 2 of the ISPOR MCDA Emerging Good Practices Task Force.

    Science.gov (United States)

    Marsh, Kevin; IJzerman, Maarten; Thokala, Praveen; Baltussen, Rob; Boysen, Meindert; Kaló, Zoltán; Lönngren, Thomas; Mussen, Filip; Peacock, Stuart; Watkins, John; Devlin, Nancy

    2016-01-01

    Health care decisions are complex and involve confronting trade-offs between multiple, often conflicting objectives. Using structured, explicit approaches to decisions involving multiple criteria can improve the quality of decision making. A set of techniques, known under the collective heading, multiple criteria decision analysis (MCDA), are useful for this purpose. In 2014, ISPOR established an Emerging Good Practices Task Force. The task force's first report defined MCDA, provided examples of its use in health care, described the key steps, and provided an overview of the principal methods of MCDA. This second task force report provides emerging good-practice guidance on the implementation of MCDA to support health care decisions. The report includes: a checklist to support the design, implementation and review of an MCDA; guidance to support the implementation of the checklist; the order in which the steps should be implemented; illustrates how to incorporate budget constraints into an MCDA; provides an overview of the skills and resources, including available software, required to implement MCDA; and future research directions. PMID:27021745

  20. Romania : Diagnostic Review of Consumer Protection and Financial Literacy, Volume 2. Comparison against Good Practices

    OpenAIRE

    World Bank

    2009-01-01

    The diagnostic review on consumer protection and financial literacy in Romania is the fourth in a World Bank-sponsored pilot program to assess consumer protection and financial literacy in developing and middle-income countries. The objective of this review are three-fold to: (1) refine a set of good practices for assessing consumer protection and financial literacy, including financial li...

  1. Creating Opportunities: Good Practice in Small Business Training for Australian Rural Women.

    Science.gov (United States)

    Simpson, Lyn; Daws, Leonie; Wood, Leanne

    2002-01-01

    To overcome barriers to participation in small business training faced by rural Australian women, training needs and delivery issues were identified and a good practice matrix was developed with the following components: marketing, content, delivery, support, impact, and innovation. Underlying principles included unique needs, diversity, use of…

  2. National benchmarking against GLOBALGAP : Case studies of Good Agricultural Practices in Kenya, Malaysia, Mexico and Chile

    NARCIS (Netherlands)

    Valk, van der O.M.C.; Roest, van der J.G.

    2009-01-01

    This desk study examines the experiences and lessons learned from four case studies of countries aiming at the GLOBALGAP benchmarking procedure for national Good Agricultural Practices, namely Chile, Kenya, Malaysia, and Mexico. Aspects that determine the origin and character of the benchmarking pro

  3. Control of good irradiation practices and the role of the ICGFI guidelines and codes

    International Nuclear Information System (INIS)

    Considerable guidance is available to managers of an irradiator plant on ways and means to produce safe, wholesome, quality irradiated foods. The foundation for good manufacturing practices (GMPs), which apply to all food processes, is the Codex General Principles of Food Hygiene. These principles provide good common sense procedures in the handling of food for human consumption in order to ensure safe, wholesome quality products. The GMPs cover the growing, harvesting, preparation, processing, packaging, storage, transport, distribution and sale of food. They provide good check lists for safety and quality. More detailed guidelines specifically aimed at food irradiation are found in the Codex Code of Practice for the Operation of Irradiation Facilities and in the Codes of Good Irradiation Practice (GIPs) developed by the International Consultative Group on Food Irradiation. GIPs are available for eight commodity groups. They provide guidance on pre-irradiation handling (including microbiological guidelines), packaging, pre-irradiation storage and transport, irradiation facilities and absorbed doses, post-irradiation storage and handling, final product specifications, labelling, re-irradiation and the quality of irradiated products. In order to apply GIPs effectively, it recommended that the Hazard Analysis Critical Control Point concept (HACCP) be implemented. The HACCP concept emphasizes prevention of, rather than detection of defects. The HACCP concept has been adopted by the Codex Alimentarius Commission and is being applied to Codex Codes of Practice. (author). 7 refs

  4. Good Clinical Practice Guidance and Pragmatic Clinical Trials: Balancing the Best of Both Worlds.

    Science.gov (United States)

    Mentz, Robert J; Hernandez, Adrian F; Berdan, Lisa G; Rorick, Tyrus; O'Brien, Emily C; Ibarra, Jenny C; Curtis, Lesley H; Peterson, Eric D

    2016-03-01

    Randomized, clinical trials are commonly regarded as the highest level of evidence to support clinical decisions. Good Clinical Practice guidelines have been constructed to provide an ethical and scientific quality standard for trials that involve human subjects in a manner aligned with the Declaration of Helsinki. Originally designed to provide a unified standard of trial data to support submission to regulatory authorities, the principles may also be applied to other studies of human subjects. Although the application of Good Clinical Practice principles generally led to improvements in the quality and consistency of trial operations, these principles have also contributed to increasing trial complexity and costs. Alternatively, the growing availability of electronic health record data has facilitated the possibility for streamlined pragmatic clinical trials. The central tenets of Good Clinical Practice and pragmatic clinical trials represent potential tensions in trial design (stringent quality and highly efficient operations). In the present article, we highlight potential areas of discordance between Good Clinical Practice guidelines and the principles of pragmatic clinical trials and suggest strategies to streamline study conduct in an ethical manner to optimally perform clinical trials in the electronic age.

  5. Nationale 'good practices' voor de VWA : studie naar drie soortgelijke autoriteiten in Nederland

    NARCIS (Netherlands)

    Wubben, E.F.M.; Hubeek, F.B.

    2005-01-01

    In 2005 is door onderzoekers van Wageningen UR en LNV DK een verkennende studie verricht: drie inspectiediensten - PD, IVW-DL en AFM - zijn verkend voor 'good practices' voor de VWA bij de herziening van het financieringsstelsel dat per 1 januari 2006, behoudens de financiële artikelen, in EU-lidsta

  6. Guideline for good evaluation practice in health informatics (GEP-HI)

    NARCIS (Netherlands)

    P. Nykanen; J. Brender; J. Talmon; N. de Keizer; M. Rigby; M.C. Beuscart-Zephir; E. Ammenwerth

    2011-01-01

    Objective: Development of a good practice guideline to plan and perform scientifically robust evaluation studies in health informatics. Methods: Issues to be addressed in evaluation studies were identified and guidance drafted based on the evaluation literature and on experiences by key players. Suc

  7. Identification of Good Practices in the Implementation of Innovative Learning Methodologies

    Science.gov (United States)

    Lincaru, Cristina; Ciuca, Vasilica; Grecu, Liliana; Atanasiu, Draga; Dragoiu, Codruta

    2011-01-01

    We intend to present the partial issues resulted from the development of the European Project DeInTRA "cooperation for innovative training methodologies deployment in the European Labour Market"--Stage 4: Identification of good practices in the implementation of innovative learning methodologies. This project is included into the Lifelong Learning…

  8. Pharmacokinetic studies of neuromuscular blocking agents : Good Clinical Research Practice (GCRP)

    NARCIS (Netherlands)

    Viby-Mogensen, J; Ostergaard, D; Donati, F; Fisher, D; Hunter, J; Kampmann, JP; Kopman, A; Proost, JH; Rasmussen, SN; Skovgaard, LT; Varin, F; Wright, PMC

    2000-01-01

    In September 1997, an international consensus conference on standardization of studies of neuromuscular blocking agents was held in Copenhagen, Denmark. Based on the conference, a set of guidelines fur good clinical research practice (GCRT) in pharmacokinetic studies of neuromuscular blocking agents

  9. Organizational interoperability in e-government lessons from 77 European good-practice cases

    CERN Document Server

    Kubicek, Herbert; Scholl, Hans Jochen

    2011-01-01

    Based on an analysis of 77 cases of good practice in e-government in Europe, this volume details the technical, organizational and legal aspects of using the internet to make government more user-friendly, providing insights into key strategic decisions.

  10. Building Skills and Qualifications among SME Employees. Leonardo da Vinci Good Practices Series.

    Science.gov (United States)

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This document profiles 10 European programs that exemplify good practice in building skills and qualifications among employees of small and medium enterprises (SMEs). The programs profiled are as follows: (1) TRICTSME (a program providing World Wide Web-based information and communication technologies training for SMEs in manufacturing); (2)…

  11. Social and Occupational Integration of Disadvantaged People. Leonardo da Vinci Good Practices Series.

    Science.gov (United States)

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This document profiles nine European programs that exemplify good practice in social and occupational integration of disadvantaged people. The programs profiled are as follows: (1) Restaurant Venezia (a CD-ROM program to improve the reading and writing skills of young people in Luxembourg who have learning difficulties); (2) an integrated…

  12. 77 FR 16158 - Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs...

    Science.gov (United States)

    2012-03-20

    ... Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs; Revision of Certain Labeling... Administration (FDA) is amending the packaging and labeling control provisions of the current good manufacturing... . SUPPLEMENTARY INFORMATION: I. Background In the Federal Register of July 29, 1997 (62 FR 40489) (the...

  13. 77 FR 49449 - Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice...

    Science.gov (United States)

    2012-08-16

    ... HUMAN SERVICES Food and Drug Administration Food and Drug Administration Clinical Trial Requirements, Compliance, and Good Clinical Practice; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public workshop. The Food and Drug Administration (FDA), Office of Regulatory Affairs...

  14. Encouraging Good Writing Practice in First-Year Psychology Students: An Intervention Using Turnitin

    Science.gov (United States)

    Betts, Lucy R.; Bostock, Stephen J.; Elder, Tracey J.; Trueman, Mark

    2012-01-01

    There is growing concern among many regarding plagiarism within student writing. This has promoted investigation into both the factors that predict plagiarism and potential methods of reducing plagiarism. Consequently, we developed and evaluated an intervention to enhance good practice within academic writing through the use of the plagiarism…

  15. Guide of good practices for occupational radiological protection in plutonium facilities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    This Technical Standard (TS) does not contain any new requirements. Its purpose is to provide guides to good practice, update existing reference material, and discuss practical lessons learned relevant to the safe handling of plutonium. the technical rationale is given to allow US Department of Energy (DOE) health physicists to adapt the recommendations to similar situations throughout the DOE complex. Generally, DOE contractor health physicists will be responsible to implement radiation protection activities at DOE facilities and DOE health physicists will be responsible for oversight of those activities. This guidance is meant to be useful for both efforts. This TS replaces PNL-6534, Health Physics Manual of Good Practices for Plutonium Facilities, by providing more complete and current information and by emphasizing the situations that are typical of DOE`s current plutonium operations; safe storage, decontamination, and decommissioning (environmental restoration); and weapons disassembly.

  16. The Availability of Original Data and Statistics: An Improvement in Good Publication Practice

    Directory of Open Access Journals (Sweden)

    Morselli-Labate AM

    2003-11-01

    Full Text Available The purpose of this paper is to highlight the aspects of good publication practices, with particular reference to data analysis, and to propose an innovative initiative for improving the quality of scientific information in this field. Several committees within the scientific community provide information and publish guidelines in order to support scientists in the application of good publication practices and to improve quality in medical research. Those guidelines suggest that the possibility of verifying the original data warrants the reliability of the published results by reducing the occurrence of misconduct related to data analysis. The initiative proposed in this article is aimed at making the original data and the statistical reports available to the scientific community together with the actual paper. Such a practice is undoubtedly an improvement in the quality of publication permitting verification of the results as well as allowing for further elaboration of the same data.

  17. Status of beryllium development for fusion applications

    Energy Technology Data Exchange (ETDEWEB)

    Billone, M.C. [Argonne National Lab., IL (United States); Donne, M.D. [Kernforschungszentrum Karlsruhe GmbH (Germany). Institut fuer Neutronphysik and Reaktortechnik; Macaulay-Newcombe, R.G. [McMaster Univ., Ontario, CA (United States). Dept. of Engineering Physics

    1994-05-01

    Beryllium is a leading candidate material for the neutron multiplier of tritium breeding blankets and the plasma facing component of first wall and divertor systems. Depending on the application, the fabrication methods proposed include hot-pressing, hot-isostatic-pressing, cold isostatic pressing/sintering, rotary electrode processing and plasma spraying. Product forms include blocks, tubes, pebbles, tiles and coatings. While, in general, beryllium is not a leading structural material candidate, its mechanical performance, as well its performance with regard to sputtering, heat transport, tritium retention/release, helium-induced swelling and chemical compatibility, is an important consideration in first-wall/blanket design. Differential expansion within the beryllium causes internal stresses which may result in cracking, thereby affecting the heat transport and barrier performance of the material. Overall deformation can result in loading of neighboring structural material. Thus, in assessing the performance of beryllium for fusion applications, it is important to have a good database in all of these performance areas, as well as a set of properties correlations and models for the purpose of interpolation/extrapolation.

  18. Taking personal responsibility: Nurses' and assistant nurses' experiences of good nursing practice in psychiatric inpatient care.

    Science.gov (United States)

    Gabrielsson, Sebastian; Sävenstedt, Stefan; Olsson, Malin

    2016-10-01

    Therapeutic nurse-patient relationships are considered essential for good nursing practice in psychiatric inpatient care. Previous research suggests that inpatient care fails to fulfil patients' expectations in this regard, and that nurses might experience the reality of inpatient care as an obstruction. The aim of the present study was to explore nurses' and assistant nurses' experiences of good nursing practice in the specific context of psychiatric inpatient care. Qualitative interviews were conducted with 12 skilled, relationship-oriented nurses and assistant nurses in order to explore their experiences with nursing practice related to psychiatric inpatient care. Interviews were transcribed and analysed using an interpretive descriptive approach. Findings describe good nursing practice as a matter of nurses and assistant nurses taking personal responsibility for their actions and for the individual patient as a person. Difficulties in providing dignified nursing care and taking personal responsibility cause them to experience feelings of distress and frustration. Shared values and nursing leadership supports being moral and treating patients with respect, having enough time supports being present and connecting with patients, and working as a part of a competent team with critical daily discussions and diversity supports being confident and building trust. The findings suggest that taking personal responsibility is integral to good nursing practice. If unable to improve poor circumstances, nurses might be forced to promote their own survival by refuting or redefining their responsibility. Nurses need to prioritize being with patients and gain support in shaping their own nursing practice. Nursing leadership should provide moral direction and defend humanistic values. PMID:27378375

  19. Taking personal responsibility: Nurses' and assistant nurses' experiences of good nursing practice in psychiatric inpatient care.

    Science.gov (United States)

    Gabrielsson, Sebastian; Sävenstedt, Stefan; Olsson, Malin

    2016-10-01

    Therapeutic nurse-patient relationships are considered essential for good nursing practice in psychiatric inpatient care. Previous research suggests that inpatient care fails to fulfil patients' expectations in this regard, and that nurses might experience the reality of inpatient care as an obstruction. The aim of the present study was to explore nurses' and assistant nurses' experiences of good nursing practice in the specific context of psychiatric inpatient care. Qualitative interviews were conducted with 12 skilled, relationship-oriented nurses and assistant nurses in order to explore their experiences with nursing practice related to psychiatric inpatient care. Interviews were transcribed and analysed using an interpretive descriptive approach. Findings describe good nursing practice as a matter of nurses and assistant nurses taking personal responsibility for their actions and for the individual patient as a person. Difficulties in providing dignified nursing care and taking personal responsibility cause them to experience feelings of distress and frustration. Shared values and nursing leadership supports being moral and treating patients with respect, having enough time supports being present and connecting with patients, and working as a part of a competent team with critical daily discussions and diversity supports being confident and building trust. The findings suggest that taking personal responsibility is integral to good nursing practice. If unable to improve poor circumstances, nurses might be forced to promote their own survival by refuting or redefining their responsibility. Nurses need to prioritize being with patients and gain support in shaping their own nursing practice. Nursing leadership should provide moral direction and defend humanistic values.

  20. Advances in participatory occupational health aimed at good practices in small enterprises and the informal sector.

    Science.gov (United States)

    Kogi, Kazutaka

    2006-01-01

    Participatory programmes for occupational risk reduction are gaining importance particularly in small workplaces in both industrially developing and developed countries. To discuss the types of effective support, participatory steps commonly seen in our "work improvement-Asia" network are reviewed. The review covered training programmes for small enterprises, farmers, home workers and trade union members. Participatory steps commonly focusing on low-cost good practices locally achieved have led to concrete improvements in multiple technical areas including materials handling, workstation ergonomics, physical environment and work organization. These steps take advantage of positive features of small workplaces in two distinct ways. First, local key persons are ready to accept local good practices conveyed through personal, informal approaches. Second, workers and farmers are capable of understanding technical problems affecting routine work and taking flexible actions leading to solving them. This process is facilitated by the use of locally adjusted training tools such as local good examples, action checklists and group work methods. It is suggested that participatory occupational health programmes can work in small workplaces when they utilize low-cost good practices in a flexible manner. Networking of these positive experiences is essential.

  1. Advances in participatory occupational health aimed at good practices in small enterprises and the informal sector.

    Science.gov (United States)

    Kogi, Kazutaka

    2006-01-01

    Participatory programmes for occupational risk reduction are gaining importance particularly in small workplaces in both industrially developing and developed countries. To discuss the types of effective support, participatory steps commonly seen in our "work improvement-Asia" network are reviewed. The review covered training programmes for small enterprises, farmers, home workers and trade union members. Participatory steps commonly focusing on low-cost good practices locally achieved have led to concrete improvements in multiple technical areas including materials handling, workstation ergonomics, physical environment and work organization. These steps take advantage of positive features of small workplaces in two distinct ways. First, local key persons are ready to accept local good practices conveyed through personal, informal approaches. Second, workers and farmers are capable of understanding technical problems affecting routine work and taking flexible actions leading to solving them. This process is facilitated by the use of locally adjusted training tools such as local good examples, action checklists and group work methods. It is suggested that participatory occupational health programmes can work in small workplaces when they utilize low-cost good practices in a flexible manner. Networking of these positive experiences is essential. PMID:16610530

  2. Good practices and health policy analysis in European sports stadia: results from the 'Healthy Stadia' project.

    Science.gov (United States)

    Drygas, Wojciech; Ruszkowska, Joanna; Philpott, Matthew; Björkström, Olav; Parker, Mike; Ireland, Robin; Roncarolo, Federico; Tenconi, Maria

    2013-06-01

    Sport plays an important role within society and sports stadia provide significant settings for public health strategies. In addition to being places of mass gathering, stadia are often located in less affluent areas and are traditionally attended by 'harder to reach' communities. Unfortunately sports stadia and the clubs they host are rarely perceived as places that promote healthy lifestyles. Fast food, alcohol and tobacco are commonly advertized, served and consumed during sports games giving the spectators and TV fans contradictory messages concerning healthy choices. As part of a wider programme of work part-funded by the European Union, a study was therefore designed to explore current 'good practice' relating to positive health interventions in sports stadia across a number of European countries. Using a specially designed questionnaire, information about health policies and good practices relating to food offerings in stadia, physical activity promotion among local communities, tobacco policy, positive mental health initiatives, environmental sustainability practices and social responsibility policies were collected in 10 European countries (England and Northern Ireland, Finland, Georgia, Greece, Ireland, Italy, Latvia, Poland, Spain and Sweden) involving 88 stadia. The audit results show that stadia health policies differ considerably between specific countries and sports. Based on the literature analysed, the examples of good practices collected through the study, and the subsequent instigation of a European Healthy Stadia Network, it shows that there is considerable potential for stadia to become health promoting settings. PMID:22139638

  3. Manual of good practices for welfare: a proposal for dairy cattle on pasture in Brazil

    Directory of Open Access Journals (Sweden)

    Ana Luiza Mendonça Pinto

    2013-11-01

    Full Text Available Debate on ethics in animal production started in 1960s. Since that time, discussion on animal welfare (AW has taken large proportions, where laws and specific rules were created in some countries. Also, this issue has been considered a major subject, and discussed in different levels such as academic, business and social spheres. Although there is a lot of information and good practice manuals for livestock production, information is still limited so that animal welfare practices can be adopted on farms effectively. Currently, the development of protocols that can assess the level of AW in properties is a reality. For dairy cattle in intensive systems, the Welfare Quality® protocol evaluates and addresses critical points so that improvement might be implemented. However, little information exists for dairy cattle in extensive systems. Thus, based on covering actions directed by the animal welfare management, behavior, nutrition, health, facilities, transportation, and human resource management, a proposal for dairy cattle on pasture in Brazil aims to provide and to disseminate good AW practices for dairy cattle on pasture. Hence, a welfare manual for good practices was created, which describes the actions and strategies to best promote the AW in this livestock production.

  4. Good Publication Practice for Communicating Company-Sponsored Medical Research: GPP3.

    Science.gov (United States)

    Battisti, Wendy P; Wager, Elizabeth; Baltzer, Lise; Bridges, Dan; Cairns, Angela; Carswell, Christopher I; Citrome, Leslie; Gurr, James A; Mooney, LaVerne A; Moore, B Jane; Peña, Teresa; Sanes-Miller, Carol H; Veitch, Keith; Woolley, Karen L; Yarker, Yvonne E

    2015-09-15

    This updated Good Publication Practice (GPP) guideline, known as GPP3, builds on earlier versions and provides recommendations for individuals and organizations that contribute to the publication of research results sponsored or supported by pharmaceutical, medical device, diagnostics, and biotechnology companies. The recommendations are designed to help individuals and organizations maintain ethical and transparent publication practices and comply with legal and regulatory requirements. These recommendations cover publications in peer-reviewed journals and presentations (oral or poster) at scientific congresses. The International Society for Medical Publication Professionals invited more than 3000 professionals worldwide to apply for a position on the steering committee, or as a reviewer, for this guideline. The GPP2 authors reviewed all applications (n = 241) and assembled an 18-member steering committee that represented 7 countries and a diversity of publication professions and institutions. From the 174 selected reviewers, 94 sent comments on the second draft, which steering committee members incorporated after discussion and consensus. The resulting guideline includes new sections (Principles of Good Publication Practice for Company-Sponsored Medical Research, Data Sharing, Studies That Should Be Published, and Plagiarism), expands guidance on the International Committee of Medical Journal Editors' authorship criteria and common authorship issues, improves clarity on appropriate author payment and reimbursement, and expands information on the role of medical writers. By following good publication practices (including GPP3), individuals and organizations will show integrity; accountability; and responsibility for accurate, complete, and transparent reporting in their publications and presentations. PMID:26259067

  5. Good Publication Practice for Communicating Company-Sponsored Medical Research: GPP3.

    Science.gov (United States)

    Battisti, Wendy P; Wager, Elizabeth; Baltzer, Lise; Bridges, Dan; Cairns, Angela; Carswell, Christopher I; Citrome, Leslie; Gurr, James A; Mooney, LaVerne A; Moore, B Jane; Peña, Teresa; Sanes-Miller, Carol H; Veitch, Keith; Woolley, Karen L; Yarker, Yvonne E

    2015-09-15

    This updated Good Publication Practice (GPP) guideline, known as GPP3, builds on earlier versions and provides recommendations for individuals and organizations that contribute to the publication of research results sponsored or supported by pharmaceutical, medical device, diagnostics, and biotechnology companies. The recommendations are designed to help individuals and organizations maintain ethical and transparent publication practices and comply with legal and regulatory requirements. These recommendations cover publications in peer-reviewed journals and presentations (oral or poster) at scientific congresses. The International Society for Medical Publication Professionals invited more than 3000 professionals worldwide to apply for a position on the steering committee, or as a reviewer, for this guideline. The GPP2 authors reviewed all applications (n = 241) and assembled an 18-member steering committee that represented 7 countries and a diversity of publication professions and institutions. From the 174 selected reviewers, 94 sent comments on the second draft, which steering committee members incorporated after discussion and consensus. The resulting guideline includes new sections (Principles of Good Publication Practice for Company-Sponsored Medical Research, Data Sharing, Studies That Should Be Published, and Plagiarism), expands guidance on the International Committee of Medical Journal Editors' authorship criteria and common authorship issues, improves clarity on appropriate author payment and reimbursement, and expands information on the role of medical writers. By following good publication practices (including GPP3), individuals and organizations will show integrity; accountability; and responsibility for accurate, complete, and transparent reporting in their publications and presentations.

  6. 78 FR 64425 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-10-29

    ... proposed rule to establish requirements for current good manufacturing practice and hazard analysis and... would create new current good manufacturing practice (CGMP) regulations that specifically address the... Manufacturing Practice and Hazard Analysis and Risk- Based Preventive Controls for Food for Animals;...

  7. A guide to good practice in modeling semantics for authors and referees

    Science.gov (United States)

    Beven, Keith; Young, Peter

    2013-08-01

    This opinion piece makes some suggestions about guidelines for modeling semantics that can be referred to by authors and referees. We discuss descriptions of model structures, different forms of simulation and prediction, descriptions of different sources of uncertainty in modeling practice, the language of model validation, and concepts of predictability and fitness-for-purpose. While not expecting universal agreement on these suggestions, given the loose usage of words in the literature, we hope that the discussion of the issues involved will at least give pause for thought and encourage good practice in model development and applications.

  8. Status of beryllium development for fusion applications

    International Nuclear Information System (INIS)

    Beryllium is a leading candidate material for the neutron multiplier of tritium breeding blankets and the plasma-facing component of first-wall and divertor systems. Depending on the application, the fabrication methods proposed include hot-pressing, hot-isostatic-pressing, cold-isostatic-pressing/sintering, rotary electrode processing and plasma spraying. Product forms include blocks, tubes, pebbles, tiles and coatings. While, in general, beryllium is not a leading structural material candidate, its mechanical performance, as well as its performance with regard to sputtering, heat transport, tritium retention/release, helium-induced swelling and chemical compatibility, is an important consideration in first-wall/blanket design. Differential expansion within the beryllium causes internal stresses which may result in cracking, thereby affecting the heat transport and barrier performance of the material. Overall deformation can result in loading of neighboring structural material. Thus, in assessing the performance of beryllium for fusion applications, it is important to have a good database in all of these performance areas, as well as a set of properties correlations and models for the purpose of interpolation/extrapolation.In this current work, the range of anticipated fusion operating conditions is reviewed. The thermal, mechanical, chemical compatibility, tritium retention/release, and helium retention/swelling databases are then reviewed for fabrication methods and fusion operating conditions of interest. Properties correlations and uncertainty ranges are also discussed. In the case of the more complex phenomena of tritium retention/release and helium-induced swelling, fundamental mechanisms and models are reviewed in more detail. Areas in which additional data are needed are highlighted, along with some trends which suggest ways of optimizing the performance of beryllium for fusion applications. (orig.)

  9. Reprocessing technology development for irradiated beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, H.; Sakamoto, N. [Oarai Research Establishment, Ibaraki-ken (Japan); Tatenuma, K. [KAKEN Co., Ibaraki-ken (Japan)] [and others

    1995-09-01

    At present, beryllium is under consideration as a main candidate material for neutron multiplier and plasma facing material in a fusion reactor. Therefore, it is necessary to develop the beryllium reprocessing technology for effective resource use. And, we have proposed reprocessing technology development on irradiated beryllium used in a fusion reactor. The preliminary reprocessing tests were performed using un-irradiated and irradiated beryllium. At first, we performed beryllium separation tests using un-irradiated beryllium specimens. Un-irradiated beryllium with beryllium oxide which is a main impurity and some other impurities were heat-treated under chlorine gas flow diluted with Ar gas. As the results high purity beryllium chloride was obtained in high yield. And it appeared that beryllium oxide and some other impurities were removed as the unreactive matter, and the other chloride impurities were separated by the difference of sublimation temperature on beryllium chloride. Next, we performed some kinds of beryllium purification tests from beryllium chloride. And, metallic beryllium could be recovered from beryllium chloride by the reduction with dry process. In addition, as the results of separation and purification tests using irradiated beryllium specimens, it appeared that separation efficiency of Co-60 from beryllium was above 96%. It is considered that about 4% Co-60 was carried from irradiated beryllium specimen in the form of cobalt chloride. And removal efficiency of tritium from irradiated beryllium was above 95%.

  10. Good control practices underlined by an on-line fuzzy control database

    Directory of Open Access Journals (Sweden)

    Alonso, M. V.

    1994-04-01

    Full Text Available In the olive oil trade, control systems that automate extraction processes, cutting production costs and increasing processing capacity without losing quality, are always desirable. The database structure of an on-line fuzzy control of centrifugation systems and the algorithms used to attain the best control conditions are analysed. Good control practices are suggested to obtain virgin olive oil of prime quality.

    In the olive oil trade, control systems that automate extraction processes, cutting production costs and increasing processing capacity without losing quality, are always desirable. The database structure of an on-line fuzzy control of centrifugation systems and the algorithms used to attain the best control conditions are analysed. Good control practices are suggested to obtain virgin olive oil of prime quality.

  11. Media fill for validation of a good manufacturing practice-compliant cell production process.

    Science.gov (United States)

    Serra, Marta; Roseti, Livia; Bassi, Alessandra

    2015-01-01

    According to the European Regulation EC 1394/2007, the clinical use of Advanced Therapy Medicinal Products, such as Human Bone Marrow Mesenchymal Stem Cells expanded for the regeneration of bone tissue or Chondrocytes for Autologous Implantation, requires the development of a process in compliance with the Good Manufacturing Practices. The Media Fill test, consisting of a simulation of the expansion process by using a microbial growth medium instead of the cells, is considered one of the most effective ways to validate a cell production process. Such simulation, in fact, allows to identify any weakness in production that can lead to microbiological contamination of the final cell product as well as qualifying operators. Here, we report the critical aspects concerning the design of a Media Fill test to be used as a tool for the further validation of the sterility of a cell-based Good Manufacturing Practice-compliant production process.

  12. Good practices with respect to the development and use of nuclear power plant procedures

    International Nuclear Information System (INIS)

    This technical publication is intended to provide information to nuclear power plant managers concerning good practices in respect to the development and use of NPP procedures. It is a part of an ongoing project on nuclear power plant instrumentation and control and is based on lessons learned from NPPs and utilities. The overall objective of this project is to provide systematic guidance on current and emerging instrumentation and control technologies including: protection and automation systems, control rooms, operator support systems, training simulators and human factors. It is intended to be applicable to NPPs in Member States that are in operation, under construction or being commissioned. The good practices described are consistent with the IAEA Safety Series recommendations with respect to the development and use of NPP procedures including the four categories: administrative procedures, operating procedures (normal, alarm response, abnormal and emergency procedures), maintenance and technical support procedures, and testing and surveillance procedures

  13. Deploying Serious Games for Management in Higher Education: lessons learned and good practices

    Directory of Open Access Journals (Sweden)

    Jannicke Baalsrud Hauge

    2014-08-01

    Full Text Available Deployment of serious games (SGs and their insertion in higher education (HE curricula is still low. The lacks papers describing deployment of SGs in HE critically showing educational benefits and providing guidelines and good practices for their use. With the present work, we intend to make a first step in this direction, by reporting our experience in using state of the art managerial SGs in MSc engineering/business courses in four different European universities. In order to describe and analyse the educational characteristics and effectiveness of each game, we propose to use two models that we have straightforwardly extracted from two major pedagogical paradigms: the Bloom’s revised cognitive learning goals taxonomy and the Kolb’s experiential learning cycle. Based on our experience, we also propose a set of lessons and good practices to incentivize and better support deployment of SGs in HE courses.

  14. Introduction and development of good practices at the Barseback nuclear power plant

    International Nuclear Information System (INIS)

    In the pursuit of high availability figures and the increase of reactor safety many different concepts contribute to the final outcome. The Barsebaeck NPP (two identical BWR units 615/615 MW) commenced commercial operation in 1975/1977. The capacity factor has been raised in the course of the years. In 1985 the maximum power level was raised by 6% and a containment venting filter was installed. A gross power production of 100 TWh was reached in October, 1988. This paper describes eight Good Practices which means technology and know-how that have been introduced and developed at our plant with the goal to achieve still better performance and safety level. These good practices and experiences are associated with modifications and backfitting

  15. Meet the good child. ‘Childing’ practices in family food co-shopping

    DEFF Research Database (Denmark)

    Gram, Malene; Grønhøj, Alice

    2016-01-01

    This article explores ‘childing’ pratices in relation to family supermarket shopping in Denmark. ‘Parenting’ practices have been explored for long but little attention has been given to how children strive to be ‘good’ children, who live up to certain standards and recognize what they perceive...... to be appropriate child and parental behavior. The study takes a practice theoretical perspective, building on previous research on family consumption, and draws empirically on 35 interviews with 5–6 year-olds and 13 family interviews. Findings show that the children recognize the position of ‘the good child......’ and most often prefer to take on this position, which is confirmed by their parents. The children can describe how ‘the good child’—in their eyes—should behave. They prefer consensus and not being embarrassing or embarrassed. The study concludes that the children are strongly immersed in social norms...

  16. Manual of Good Practice in Food Irradiation. Sanitary, Phytosanitary and Other Applications

    International Nuclear Information System (INIS)

    Ensuring that the process of irradiating food delivers the desired result consistently is essential for the correct application of the technology and will help to inspire consumer confidence in irradiated food. This publication aims to help operators of irradiation facilities to appreciate and improve their practices and also to provide detailed, yet straightforward, technical information for stakeholders such as food regulators, manufacturers and traders, who also need to understand ‘good practice’

  17. Goodnip - Good Practices in Nordic Innovation Policies. Part 2: Innovation Policy Trends and Rationalities

    OpenAIRE

    Koch, Per; Oksanen, Juha

    2003-01-01

    The main objective of Good Practices in Nordic Innovation Policies has been to develop a survey and an analysis of Nordic innovation policy instruments that directly or indirectly are targeting small and medium sized enterprises. The project is to provide Nordic policy makers with information to be used in the development of new or adjusted policy instruments on a national or Nordic level. The project unites researchers from the five Nordic countries: Norway, Iceland, Finland, Denmark, and Sw...

  18. Does 'Best Practice' in Setting Executive Pay in the UK Encourage 'Good' Behaviour?

    OpenAIRE

    Bender, Ruth; Moir, Lance

    2006-01-01

    We examine how UK listed companies set executive pay, reviewing the implications of following best practice in corporate governance and examining how this can conflict with what shareholders and other stakeholders might perceive as good behaviour. We do this by considering current governance regulation in the light of interviews with protagonists in the debate, setting out the dilemmas faced by remuneration-setters, and showing how the processes they follow can lead to ethic...

  19. The contribution of analytical detection methods to the enforcement of good irradiation practice

    International Nuclear Information System (INIS)

    Good Manufacturing Practice (GMP) is a generally accepted principle combining several features in order to achieve the optimal quality. In other words, GMP is observed if every possible measure is taken to contribute to the best possible quality of the end product. In this sense, Good Irradiation Practice (GIP) may be understood as one of the many elements of GMP dealing especially with aspects of processing food using ionising radiation. On the contrary the operator of an irradiation facility may consider GIP as the central idea including that GMP - in this case excluding the radiation aspects - is observed in addition to GIP standards. Regardless of this theoretical dispute, it is obvious that food irradiation requires classical GMP to be applied without exception and that good practice is also applied in radiation processing. The main interest in analytical methods for the identification of radiation processed food arose from the need to enforce the ban on this process, to verify correct labelling, or to ensure that it is used only for the very limited number of application which are permitted. In this field, identification methods already introduced into the official food inspection systems have contributed considerably towards making evident several cases of the fraudulent application of radiation processing. At present, as radiation processing of food is becoming more and more accepted, the number of national clearances is increasing and the European Community is preparing for a Directive to harmonise the food laws of the member states with regard to food irradiation. Therefore, it should be considered how the analytical detection methods which have been developed could contribute to enforcing good manufacturing practices, once the main goal ceases to be the suppression of this process. (author)

  20. Good practices in team teaching in Japan, South Korea and Hong Kong

    OpenAIRE

    Carless, DR

    2006-01-01

    Team teaching between native English speaking teachers and local L2 English teachers has become an increasingly common phenomenon in schooling in the East Asia region. The relevant literature reports some positive impacts of team teaching and also highlights some of the challenges or conflicts which arise. The aim of this paper is to focus on reporting and analysing good practices in intercultural team teaching. I draw on interviews and classroom observations from three schemes in which nativ...

  1. Adoption of Good Agricultural Practices by Durian Farmers in Koh Samui District, Surat Thani Province, Thailand

    OpenAIRE

    MANKEB, Panya; LIMUNGGURA, Tippawan; IN-GO, Anuson; CHULILUNG, Praporn

    2014-01-01

    Durian (Durio zibethinus Murr.) is famous as the “king of fruits” and Thailand’s economicallyimportant fruit for export. As consumer demand for high quality and safe food products increased, GoodAgricultural Practices (GAP) were adopted by durian farmers in Koh Sumui district, Surat Thani province,Thailand to produce safe and wholesome fruits. The purposes of this research were to study the adoption ofGAP and to determine factors affecting GAP adoption of durian farmers. Structure interview w...

  2. The Conduct of Drug Metabolism Studies Considered Good Practice (II): In Vitro Experiments

    OpenAIRE

    Jia, Lee; LIU, XIAODONG

    2007-01-01

    In vitro drug metabolism studies, which are inexpensive and readily carried out, serve as an adequate screening mechanism to characterize drug metabolites, elucidate their pathways, and make suggestions for further in vivo testing. This publication is a sequel to part I in a series and aims at providing a general framework to guide designs and protocols of the in vitro drug metabolism studies considered good practice in an efficient manner such that it would help researchers avoid common pitf...

  3. Good Global Legal Practices to Promote Gender Equality in the Labor Market

    OpenAIRE

    Asian Development Bank

    2013-01-01

    Increasing job opportunities and decent work for women are essential for advancing economic and social development in countries, because many women continue to experience gender inequalities at work. An analysis of strategies to counter gender discrimination and promote equality between men and women shows how a combination of good practices in law and in social and economic policy can improve equitable employment opportunities, remuneration,and treatment for women and men at work. This repor...

  4. Good Global Economic and Social Practices to Promote Gender Equality in the Labor Market

    OpenAIRE

    Asian Development Bank

    2013-01-01

    Increasing job opportunities and decent work for women are essential for advancing economic and social development in countries, because many women continue to experience gender inequalities at work. An analysis of strategies to counter gender discrimination and promote equality between men and women shows how a combination of good practices in law and in social and economic policy can improve equitable employment opportunities, remuneration, and treatment for women and men at work. This repo...

  5. Water use and quality in life cycle assessment: identifying good practices and developing operational spatial approaches

    OpenAIRE

    Kounina, Anna

    2014-01-01

    Pressure on freshwater resources is increasingly covered by methodological developments addressing freshwater use in the field of Life Cycle Assessment (LCA). These developments ultimately lead to the publication of the ISO 14046 standard to define the principles, requirement and guidelines for a water footprint in August 2014. The objective of this thesis is to foster the application of water footprint by identifying good practices and developing operational approaches to assess and improve ...

  6. A systematic approach to initial data analysis is good research practice.

    Science.gov (United States)

    Huebner, Marianne; Vach, Werner; le Cessie, Saskia

    2016-01-01

    Initial data analysis is conducted independently of the analysis needed to address the research questions. Shortcomings in these first steps may result in inappropriate statistical methods or incorrect conclusions. We outline a framework for initial data analysis and illustrate the impact of initial data analysis on research studies. Examples of reporting of initial data analysis in publications are given. A systematic and careful approach to initial data analysis is needed as good research practice.

  7. National benchmarking against GLOBALGAP : Case studies of Good Agricultural Practices in Kenya, Malaysia, Mexico and Chile

    OpenAIRE

    Valk, van der, L.J.M.; Roest, De, Kees

    2009-01-01

    This desk study examines the experiences and lessons learned from four case studies of countries aiming at the GLOBALGAP benchmarking procedure for national Good Agricultural Practices, namely Chile, Kenya, Malaysia, and Mexico. Aspects that determine the origin and character of the benchmarking process are the current and future export markets of each country; the ownership of the National GAP Schemes, that is, government or private sector. Government led GAP initiatives are part of strategi...

  8. Guide to good practices for training and qualification of instructors. DOE handbook

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Purpose of this guide is to provide contractor training organizations with information that can be used to verify the adquacy and/or modify existing instructor training programs, or to develop new training programs. It contains good practices for the training and qualification of technical instructors and instructional technologists at DOE reactor and non-reactor nuclear facilities. It addresses the content of initial and continuing instructor training programs, evaluation of instructor training programs, and maintenance of instructor training records.

  9. Aerosols generated during beryllium machining.

    Science.gov (United States)

    Martyny, J W; Hoover, M D; Mroz, M M; Ellis, K; Maier, L A; Sheff, K L; Newman, L S

    2000-01-01

    Some beryllium processes, especially machining, are associated with an increased risk of beryllium sensitization and disease. Little is known about exposure characteristics contributing to risk, such as particle size. This study examined the characteristics of beryllium machining exposures under actual working conditions. Stationary samples, using eight-stage Lovelace Multijet Cascade Impactors, were taken at the process point of operation and at the closest point that the worker would routinely approach. Paired samples were collected at the operator's breathing zone by using a Marple Personal Cascade Impactor and a 35-mm closed-faced cassette. More than 50% of the beryllium machining particles in the breathing zone were less than 10 microns in aerodynamic diameter. This small particle size may result in beryllium deposition into the deepest portion of the lung and may explain elevated rates of sensitization among beryllium machinists.

  10. Going GLP: Conducting Toxicology Studies in Compliance with Good Laboratory Practices.

    Science.gov (United States)

    Carroll, Erica Eggers

    2016-01-01

    Good laboratory practice standards are US federal regulations enacted as part of the Federal Insecticide, Fungicide, and Rodenticide Act (40 CFR Part 160), the Toxic Substance Control Act (40 CFR Part 792), and the Good Laboratory Practice for Nonclinical Laboratory Studies (21 CFR Part 58) to support protection of public health in the areas of pesticides, chemicals, and drug investigations in response to allegations of inaccurate data acquisition. Essentially, good laboratory practices (GLPs) are a system of management controls for nonclinical research studies involving animals to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of data collected as part of chemical (including pharmaceuticals) tests, from in vitro through acute to chronic toxicity tests. The GLPs were established in the United States in 1978 as a result of the Industrial Bio-Test Laboratory scandal which led to congressional hearings and actions to prevent fraudulent data reporting and collection. Although the establishment of infrastructure for GLPs compliance is labor-intensive and time-consuming, achievement and maintenance of GLP compliance ensures the accuracy of the data collected from each study, which is critical for defending results, advancing science, and protecting human and animal health. This article describes how and why those in the US Army Medical Department responsible for protecting the public health of US Army and other military personnel made the policy decision to have its toxicology laboratory achieve complete compliance with GLP standards, the first such among US Army laboratories. The challenges faced and how they were overcome are detailed. PMID:27613211

  11. Teachers’ attitudes toward ICT in good practice teaching in schools with inclusive orientation

    Directory of Open Access Journals (Sweden)

    José M.ª FERNÁNDEZ BATANERO

    2013-01-01

    Full Text Available The present paper puts forward the result of a study aimed at analysing teachers’ attitudes towards the use and integration of Information and Communication Technologies (ICT in the classroom, as well as identifying the factors that favour ICT based good educational practices. This is a multiple case study developed in two public compulsory-secondaryeducation centres in Seville (Spain. The following criterion was born in mind for case selection: both centres focus on guidance for inclusive education and their good practices have been certified by the Andalusian Educational Authority. The techniques for information collection include a questionnaire and a discussion group. Results point out that, on one hand, teachers generally have positive attitudes towards ICT, particularly male teachers and those more usually in contact with these technologies. On the other hand, counting with enough materials and resources, giving importance to constructivism, adapting activities and exercises to the students’ features, and stimulating their learning autonomy and collaborative work –as well as the promotion of inclusive policies and cultures in educational centres– are proven important factors to develop ICT based good educational practices.

  12. Beryllium. Its minerals. Pt. 1

    International Nuclear Information System (INIS)

    With this work a series of reports begins, under the generic name 'Beryllium', related to several aspects of beryllium technology. The target is to update, with critical sense, current bibliographic material in order to be used in further applications. Some of the most important beryllium ores, the Argentine emplacement of their deposits and world occurrence are described. Argentine and world production, resources and reserves are indicated here as well. (Author)

  13. EXAMPLES OF GOOD PRACTICE NEEDED IN IMPLEMENTATION OF THE EUROPEAN FUNDS

    Directory of Open Access Journals (Sweden)

    CEAUSESCU IONUT

    2016-08-01

    Full Text Available The main purpose of this study is to capture theoretically and practically the main issues in good practices that can underpin a better absorption of European funds in Romania. Also in this paper, we treated a number of issues related to cohesion policy, given that, as we all know, cohesion policy is an essential tool for investment, growth and jobs in EU level and for structural reforms in the Member States. Also, cohesion policy contributes to the Europe 2020 strategy for smart, sustainable and inclusive growth throughout the European Union. For example, the policy seeks to pursue the following goals: "Investment for growth and jobs" in Member States and regions, benefiting from contributions from all funds and "European territorial cooperation", benefiting from contributions from the ERDF. In essence, it works for the submission of examples of best practices encountered in countries with high degree of absorption of structural funds and that can be implemented in the Romanian legislation.

  14. Evaluation of the Implementation of Good Handling Practices in Food and Beverage Areas of Hotels.

    Science.gov (United States)

    Serafim, A L; Hecktheuer, L H R; Stangarlin-Fiori, L; Medeiros, L B; Martello, L; Machado, C E

    2015-11-01

    Because of the major international-level events that have recently been held in Brazil, concerns about the sensory and hygienic-sanitary conditions of food have increased. The objective of this study was to evaluate the implementation of good handling practices in food and beverage areas of hotels, with and without outsourced professional intervention. We evaluated 19 food and beverage areas in hotels in Porto Alegre, Rio do Sul, Brazil, using a checklist that was developed by a municipal surveillance team based on existing laws for good handling practices. The evaluation was done by a skilled professional in the food safety area on two occasions, at the beginning of the study (January to May 2013) and at the end (July to November 2014), and the establishments were classified as good, regular, or poor. After the baseline evaluation, an action plan listing the noncompliance found at each location was given to those responsible for the establishments, and a period of 1 year 6 months was stipulated for improvements to be made. In the repeat evaluation, those responsible for the establishments were asked whether they had hired an outsourced professional to assist them in the improvements. The hotels showed improvement during the repeat evaluation, but a significant increase in the percentage of overall adequacy was seen only in the food and beverages areas of the 12 hotels that used the intervention of an outsourced professional. The better percentage of adequacy in establishments with outsourced professional intervention underlines the importance of an external and impartial view of routine activities in the implementation of good handling practices.

  15. Evaluation of the Implementation of Good Handling Practices in Food and Beverage Areas of Hotels.

    Science.gov (United States)

    Serafim, A L; Hecktheuer, L H R; Stangarlin-Fiori, L; Medeiros, L B; Martello, L; Machado, C E

    2015-11-01

    Because of the major international-level events that have recently been held in Brazil, concerns about the sensory and hygienic-sanitary conditions of food have increased. The objective of this study was to evaluate the implementation of good handling practices in food and beverage areas of hotels, with and without outsourced professional intervention. We evaluated 19 food and beverage areas in hotels in Porto Alegre, Rio do Sul, Brazil, using a checklist that was developed by a municipal surveillance team based on existing laws for good handling practices. The evaluation was done by a skilled professional in the food safety area on two occasions, at the beginning of the study (January to May 2013) and at the end (July to November 2014), and the establishments were classified as good, regular, or poor. After the baseline evaluation, an action plan listing the noncompliance found at each location was given to those responsible for the establishments, and a period of 1 year 6 months was stipulated for improvements to be made. In the repeat evaluation, those responsible for the establishments were asked whether they had hired an outsourced professional to assist them in the improvements. The hotels showed improvement during the repeat evaluation, but a significant increase in the percentage of overall adequacy was seen only in the food and beverages areas of the 12 hotels that used the intervention of an outsourced professional. The better percentage of adequacy in establishments with outsourced professional intervention underlines the importance of an external and impartial view of routine activities in the implementation of good handling practices. PMID:26555528

  16. Problems and future plan on material development of beryllium in materials testing reactors

    International Nuclear Information System (INIS)

    Beryllium has been utilized as a moderator and/or reflector in a number of material testing reactors. The attractive nuclear properties of beryllium are its low atomic number, low atomic weight, low parasitic capture cross section for thermal neutrons, readiness to part with one of its own neutrons, and good neutron elastic scattering characteristics. However, it is difficult to reprocess irradiated beryllium because of high induced radioactivity. Disposal has also been difficult because of toxicity issues and special nuclear material controls. In this paper, problems and future plans of beryllium technology are introduced for nuclear reactors. (author)

  17. The beryllium quandary: will the lower exposure limits spur new developments in sampling and analysis?

    Energy Technology Data Exchange (ETDEWEB)

    Brisson, Michael

    2013-06-03

    At the time this article was written, new rulemakings were under consideration at OSHA and the U.S. Department of Energy (DOE) that would propose changes to occupational exposure limits for beryllium. Given these developments, it’s a good time to review the tools and methods available to IHs for assessing beryllium air and surface contamination in the workplace—what’s new and different, and what’s tried and true. The article discusses limit values and action levels for beryllium, problematic aspects of beryllium air sampling, sample preparation, sample analysis, and data evaluation.

  18. Joining of Beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, A

    2006-02-01

    A handbook dealing with the many aspects of beryllium that would be important for the users of this metal is currently being prepared. With an introduction on the applications, advantages and limitations in the use of this metal the following topics will be discussed in this handbook: physical, thermal, and nuclear properties; extraction from the ores; purification and casting of ingots; production and types of beryllium powders; consolidation methods, grades, and properties; mechanical properties with emphasis on the various factors affecting these properties; forming and mechanical working; welding, brazing, bonding, and fastening; machining; powder deposition; corrosion; health aspects; and examples of production of components. This report consists of ''Section X--Joining'' from the handbook. The prefix X is maintained here for the figures, tables and references. In this section the different methods used for joining beryllium and the advantages, disadvantages and limitations of each are presented. The methods discussed are fusion welding, brazing, solid state bonding (diffusion bonding and deformation bonding), soldering, and mechanical fastening. Since beryllium has a high affinity for oxygen and nitrogen with the formation of oxides and nitrides, considerable care must be taken on heating the metal, to protect it from the ambient atmosphere. In addition, mating surfaces must be cleaned and joints must be designed to minimize residual stresses as well as locations for stress concentration (notch effects). In joining any two metals the danger exists of having galvanic corrosion if the part is subjected to moisture or to any type of corroding environment. This becomes a problem if the less noble (anodic) metal has a significantly smaller area than the more noble (cathodic) metal since the ions (positive charges) from the anodic (corroding) metal must correspond to the number of electrons (negative charges) involved at the cathode. Beryllium

  19. Electroencephalographic neurofeedback: Level of evidence in mental and brain disorders and suggestions for good clinical practice.

    Science.gov (United States)

    Micoulaud-Franchi, J-A; McGonigal, A; Lopez, R; Daudet, C; Kotwas, I; Bartolomei, F

    2015-12-01

    The technique of electroencephalographic neurofeedback (EEG NF) emerged in the 1970s and is a technique that measures a subject's EEG signal, processes it in real time, extracts a parameter of interest and presents this information in visual or auditory form. The goal is to effectuate a behavioural modification by modulating brain activity. The EEG NF opens new therapeutic possibilities in the fields of psychiatry and neurology. However, the development of EEG NF in clinical practice requires (i) a good level of evidence of therapeutic efficacy of this technique, (ii) a good practice guide for this technique. Firstly, this article investigates selected trials with the following criteria: study design with controlled, randomized, and open or blind protocol, primary endpoint related to the mental and brain disorders treated and assessed with standardized measurement tools, identifiable EEG neurophysiological targets, underpinned by pathophysiological relevance. Trials were found for: epilepsies, migraine, stroke, chronic insomnia, attentional-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, major depressive disorder, anxiety disorders, addictive disorders, psychotic disorders. Secondly, this article investigates the principles of neurofeedback therapy in line with learning theory. Different underlying therapeutic models are presented didactically between two continua: a continuum between implicit and explicit learning and a continuum between the biomedical model (centred on "the disease") and integrative biopsychosocial model of health (centred on "the illness"). The main relevant learning model is to link neurofeedback therapy with the field of cognitive remediation techniques. The methodological specificity of neurofeedback is to be guided by biologically relevant neurophysiological parameters. Guidelines for good clinical practice of EEG NF concerning technical issues of electrophysiology and of learning are suggested. These require validation by

  20. Beryllium. Beryllium oxide, obtention and properties. Pt.4

    International Nuclear Information System (INIS)

    As a continuation of the 'Beryllium' series this work reviews several methods of high purity beryllia production. Diverse methods of obtention and purification from different beryllium compounds are described. Some chemical, mechanical and electrical properties related with beryllia obtention methods are summarized. (Author)

  1. Health physics manual of good practices for plutonium facilities. [Contains glossary

    Energy Technology Data Exchange (ETDEWEB)

    Brackenbush, L.W.; Heid, K.R.; Herrington, W.N.; Kenoyer, J.L.; Munson, L.F.; Munson, L.H.; Selby, J.M.; Soldat, K.L.; Stoetzel, G.A.; Traub, R.J.

    1988-05-01

    This manual consists of six sections: Properties of Plutonium, Siting of Plutonium Facilities, Facility Design, Radiation Protection, Emergency Preparedness, and Decontamination and Decommissioning. While not the final authority, the manual is an assemblage of information, rules of thumb, regulations, and good practices to assist those who are intimately involved in plutonium operations. An in-depth understanding of the nuclear, physical, chemical, and biological properties of plutonium is important in establishing a viable radiation protection and control program at a plutonium facility. These properties of plutonium provide the basis and perspective necessary for appreciating the quality of control needed in handling and processing the material. Guidance in selecting the location of a new plutonium facility may not be directly useful to most readers. However, it provides a perspective for the development and implementation of the environmental surveillance program and the in-plant controls required to ensure that the facility is and remains a good neighbor. The criteria, guidance, and good practices for the design of a plutonium facility are also applicable to the operation and modification of existing facilities. The design activity provides many opportunities for implementation of features to promote more effective protection and control. The application of ''as low as reasonably achievable'' (ALARA) principles and optimization analyses are generally most cost-effective during the design phase. 335 refs., 8 figs., 20 tabs.

  2. Team Science Approach to Developing Consensus on Research Good Practices for Practice-Based Research Networks: A Case Study.

    Science.gov (United States)

    Campbell-Voytal, Kimberly; Daly, Jeanette M; Nagykaldi, Zsolt J; Aspy, Cheryl B; Dolor, Rowena J; Fagnan, Lyle J; Levy, Barcey T; Palac, Hannah L; Michaels, LeAnn; Patterson, V Beth; Kano, Miria; Smith, Paul D; Sussman, Andrew L; Williams, Robert; Sterling, Pamela; O'Beirne, Maeve; Neale, Anne Victoria

    2015-12-01

    Using peer learning strategies, seven experienced PBRNs working in collaborative teams articulated procedures for PBRN Research Good Practices (PRGPs). The PRGPs is a PBRN-specific resource to facilitate PBRN management and staff training, to promote adherence to study protocols, and to increase validity and generalizability of study findings. This paper describes the team science processes which culminated in the PRGPs. Skilled facilitators used team science strategies and methods from the Technology of Participation (ToP®), and the Consensus Workshop Method to support teams to codify diverse research expertise in practice-based research. The participatory nature of "sense-making" moved through identifiable stages. Lessons learned include (1) team input into the scope of the final outcome proved vital to project relevance; (2) PBRNs with diverse domains of research expertise contributed broad knowledge on each topic; and (3) ToP® structured facilitation techniques were critical for establishing trust and clarifying the "sense-making" process.

  3. English Language Perplexity: articulating the tensions in the AUQA Good Practice Principles

    Directory of Open Access Journals (Sweden)

    Rowena Harper

    2011-02-01

    Full Text Available In 2009, the Australian Universities Quality Agency (AUQA published the Good practice principles for English language proficiency for international students in Australian universities.  While the sector has generally welcomed these Good Practice Principles (GPPs, universities have been somewhat slow in implementing them and the literature has remained relatively silent in response.  One important article—Murray (2010, published in The International Journal of the First Year in Higher Education—discusses several problems inherent in the report in order to recommend a coherent approach to implementing the guidelines.  This paper challenges aspects of Murray’s article and extends his critique of the AUQA GPPs by focussing on three key points of tension: the group of students the report discusses; its definition of English language proficiency, and its conflicting discourses of inclusion and exclusion.  The aim here is to offer universities points for discussion as they work to translate this complex report into practice.

  4. Impurities effect on the swelling of neutron irradiated beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Donne, M.D.; Scaffidi-Argentina, F. [Institut fuer Neutronenphysik und Reaktortechnik, Karlsruhe (Germany)

    1995-09-01

    An important factor controlling the swelling behaviour of fast neutron irradiated beryllium is the impurity content which can strongly affect both the surface tension and the creep strength of this material. Being the volume swelling of the old beryllium (early sixties) systematically higher than that of the more modem one (end of the seventies), a sensitivity analysis with the aid of the computer code ANFIBE (ANalysis of Fusion Irradiated BEryllium) to investigate the effect of these material properties on the swelling behaviour of neutron irradiated beryllium has been performed. Two sets of experimental data have been selected: the first one named Western refers to quite recently produced Western beryllium, whilst the second one, named Russian refers to relatively old (early sixties) Russian beryllium containing a higher impurity rate than the Western one. The results obtained with the ANFIBE Code were assessed by comparison with experimental data and the used material properties were compared with the data available in the literature. Good agreement between calculated and measured values has been found.

  5. Technical Basis for PNNL Beryllium Inventory

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Michelle Lynn

    2014-07-09

    The Department of Energy (DOE) issued Title 10 of the Code of Federal Regulations Part 850, “Chronic Beryllium Disease Prevention Program” (the Beryllium Rule) in 1999 and required full compliance by no later than January 7, 2002. The Beryllium Rule requires the development of a baseline beryllium inventory of the locations of beryllium operations and other locations of potential beryllium contamination at DOE facilities. The baseline beryllium inventory is also required to identify workers exposed or potentially exposed to beryllium at those locations. Prior to DOE issuing 10 CFR 850, Pacific Northwest Nuclear Laboratory (PNNL) had documented the beryllium characterization and worker exposure potential for multiple facilities in compliance with DOE’s 1997 Notice 440.1, “Interim Chronic Beryllium Disease.” After DOE’s issuance of 10 CFR 850, PNNL developed an implementation plan to be compliant by 2002. In 2014, an internal self-assessment (ITS #E-00748) of PNNL’s Chronic Beryllium Disease Prevention Program (CBDPP) identified several deficiencies. One deficiency is that the technical basis for establishing the baseline beryllium inventory when the Beryllium Rule was implemented was either not documented or not retrievable. In addition, the beryllium inventory itself had not been adequately documented and maintained since PNNL established its own CBDPP, separate from Hanford Site’s program. This document reconstructs PNNL’s baseline beryllium inventory as it would have existed when it achieved compliance with the Beryllium Rule in 2001 and provides the technical basis for the baseline beryllium inventory.

  6. From bad pharma to good pharma: aligning market forces with good and trustworthy practices through accreditation, certification, and rating.

    Science.gov (United States)

    Miller, Jennifer E

    2013-01-01

    This article explores whether the bioethical performance and trustworthiness of pharmaceutical companies can be improved by harnessing market forces through the use of accreditation, certification, or rating. Other industries have used such systems to define best practices, set standards, and assess and signal the quality of services, processes, and products. These systems have also informed decisions in other industries about where to invest, what to buy, where to work, and when to regulate. Similarly, accreditation, certification, and rating programs can help drug companies address stakeholder concerns in four areas: clinical trial design and management, dissemination of clinical trial results, marketing practices, and the accessibility of medicines. To illuminate processes - such as conflicts of interests and revolving-door policies - that can jeopardize the integrity of accreditation, certification, and ratings systems, the article concludes with a consideration of recent failures of credit-rating agencies and a review of the regulatory capture literature. PMID:24088150

  7. Good Practice in Designing and Implementing National Monitoring Systems for Adaptation to Climate Change

    DEFF Research Database (Denmark)

    Naswa, Prakriti; Trærup, Sara Lærke Meltofte; Bouroncle, Claudia;

    In this report, we identify, analyse and compare international good practices in the design and implementation of national monitoring and evaluating indicator systems for climate change adaptation. This first chapter provides an introduction to the context and key terminology in the domain...... of climate change adaptation and indicators for M&E of adaptation. The second chapter discusses the existing approaches to M&E, while Chapter 3 provides a general overview of approaches to M&E Frameworks for Climate Change Adaptation. Chapters 4 and 5 outline and discuss the application and relevance...

  8. Verification of good production practices that reduce the risk of exposure of pigs to Trichinella

    Directory of Open Access Journals (Sweden)

    Gamble H.R.

    2001-06-01

    Full Text Available Control of Trichinella infection in swine has traditionally been accomplished by inspection of individual carcasses or by post-slaughter processing to inactivate parasites. Recent declines in prevalence of this parasite in domestic swine, coupled with improvements in swine management systems, offer the opportunity to document pork safety during the production phase. We report here on a certification pilot study using an audit to document good production practices for swine relative to the risk of exposure to trichinae. Based on the results, improvements in the program have been made and further studies will be undertaken prior to launching a voluntary trichinae herd certification program in the United States.

  9. A goat's head on a sheep's body? Manufacturing good practices for Tibetan medicine.

    Science.gov (United States)

    Saxer, Martin

    2012-01-01

    The production of Tibetan pharmaceuticals underwent a far-reaching transformation over the past decade. The introduction of good manufacturing practices (GMP) marked the beginning of rapid industrialization: new factories were built, and the companies re-oriented themselves to the requirements of the market. While officially regarded a great success, many doctors and pharmacists see GMP as fundamentally incompatible with traditional production methods and notions of quality. In this article, I address this incompatibility and examine where and how it affects the actual practice of producing medicines. While the problem exists, I argue that it does not stem from conflicting epistemologies but rather from the side effects of a quick and forced implementation, which often contradicts the spirit and letter of the regulations themselves. The case sheds new light on the way in which ideas about quality and safety, forged in the global arena, are locally recontextualized.

  10. Developing a Framework for Evaluating Ethical Outcomes of Good Participatory Practices in TB Clinical Drug Trials.

    Science.gov (United States)

    MacQueen, Kathleen M; Eley, Natalie T; Frick, Mike; Mingote, Laia Ruiz; Chou, Alicia; Seidel, Stephanie S; Hannah, Stacey; Hamilton, Carol

    2016-07-01

    Good Participatory Practice Guidelines for TB Drug Trials (GPP-TB) were issued in 2012, based on similar guidelines for HIV prevention and reflecting growing acceptance of the importance of community engagement and participatory strategies in clinical research. Though the need for such strategies is clear, evaluation of the benefits and burdens are needed. Working with a diverse group of global TB stakeholders including advocates, scientists, and ethicists, we used a Theory of Change approach to develop an evaluation framework for GPP-TB that includes a clearly defined ethical goal, a set of powerful strategies derived from GPP-TB practices for achieving the goal, and outcomes connecting strategies to goal. The framework is a first step in systematically evaluating participatory research in clinical trials. PMID:27368311

  11. Developing a Framework for Evaluating Ethical Outcomes of Good Participatory Practices in TB Clinical Drug Trials.

    Science.gov (United States)

    MacQueen, Kathleen M; Eley, Natalie T; Frick, Mike; Mingote, Laia Ruiz; Chou, Alicia; Seidel, Stephanie S; Hannah, Stacey; Hamilton, Carol

    2016-07-01

    Good Participatory Practice Guidelines for TB Drug Trials (GPP-TB) were issued in 2012, based on similar guidelines for HIV prevention and reflecting growing acceptance of the importance of community engagement and participatory strategies in clinical research. Though the need for such strategies is clear, evaluation of the benefits and burdens are needed. Working with a diverse group of global TB stakeholders including advocates, scientists, and ethicists, we used a Theory of Change approach to develop an evaluation framework for GPP-TB that includes a clearly defined ethical goal, a set of powerful strategies derived from GPP-TB practices for achieving the goal, and outcomes connecting strategies to goal. The framework is a first step in systematically evaluating participatory research in clinical trials.

  12. Determination of beryllium by using X-ray fluorescence spectrometry.

    Science.gov (United States)

    Zawisza, Beata

    2008-03-01

    X-ray fluorescence spectrometry method is subject to certain difficulties and inconveniences for the elements having the atomic number 9 or less. These difficulties become progressively more severe as the atomic number decreases, and are quite serious for beryllium, which is practically indeterminable directly by XRF. Therefore, an indirect determination of beryllium that is based on the evaluation of cobalt in the precipitate is taken into consideration. In the thesis below, there is a description of a new, simple, and precise method by selective precipitation using hexamminecobalt(III) chloride and ammonium carbonate-EDTA solution as a complexing agent for the determining of a trace amount of beryllium using X-ray fluorescence spectrometry. The optimum conditions for [Co(NH(3))(6)][Be(2)(OH)(3)(CO(3))(2)(H(2)O)(2)].(3)H(2)O complex formation were studied. The complex was collected on the membrane filter, and the Co Kalpha line was measured by XRF. The method presents the advantages of the sample preparation and the elimination of the matrix effects due to the thin film obtained. The detection limit of the proposed method is 0.2 mg of beryllium. The method was successfully applied to beryllium determination in copper/ beryllium/cobalt alloys.

  13. Guidance for health and social care providers, principles of good practice in medication reconciliation

    LENUS (Irish Health Repository)

    Hill, F

    2012-02-01

    The predicted prevalence of diabetes in Ireland by 2015 is 190,000. Structured diabetes care in general practice has outcomes equivalent to secondary care and good diabetes care has been shown to be associated with the use of electronic healthcare records (EHRs). This automated analysis of EHRs in 23 practices took 10 minutes per practice compared with 15 hours per practice for manual searches. Data was extracted for 1901 type II diabetics. There was valid data for >80% of patients for 6 of the 9 key indicators in the previous year. 543 (34%) had a Hba1c > 7.5%, 142 (9%) had a total cholesterol >6 mmol\\/l, 83 (6%) had an LDL cholesterol >4 mmol\\/l, 367 (22%) had Triglycerides > 2.2 mmol\\/l and 162 (10%) had Blood Pressure > 160\\/100 mmHg. Data quality and key indicators of care compare well with manual audits in Ireland and the U.K. electronic healthcare records and automated audits should be a feature of all chronic disease management programs.

  14. Vendor managed inventory (VMI practice analysis in a supplier of consumer goods

    Directory of Open Access Journals (Sweden)

    Denise Cervilha Freitas

    2014-08-01

    Full Text Available One of the widely discussed collaborative practices in the literature is Vendor Managed Inventory (VMI, which gives supplier the freedom to take decisions regarding customer´s replenishment, allowing better production planning. Despite the efforts of many researches, few studies compare the reality faced by companies with theories in the literature. Thus, this research aims to analyze the VMI practice of a consumer goods supplier with its retail customer, based on the barriers that limit the potential results of the practice and also the critical factors for the success of VMI. Insights from this analysis resulted in some propositions for future studies. The literature review allowed the identification of elements that influence the adoption and maintenance of VMI that were grouped into behavioral, cultural and physical elements. The method used was a case study with in-depth interviews, which allowed identifying the elements that limit the potential gains of VMI in the analyzed company and also those ones that contribute to the success of the practice.

  15. ADOPTION OF GOOD MANAGEMENT PRACTICE (GMP) IN SMALL AND MEDIUM SCALE VANNAMEI SHRIMP FARMS ON THE NORTHERN SHORE EAST JAVA

    OpenAIRE

    Paula Florina; Sri Hartoyo; Sukardi Sukardi

    2012-01-01

    The objectives of this research were to describe the value chain of Vannamei shrimp industry on the northern shore of East Java, to identify the current management practice that is being implemented by small to medium scale shrimp farmers, to analyze the level of adoption of Good Management Practice by small to medium scale shrimp farmers and to identify the challenges that prevent small to medium scale farmers from adopting Good Management Practice. This research utilized descriptive qualita...

  16. Approach Regarding a Framework for Risk Reporting in Order to Enhance the Related Good Practices

    Directory of Open Access Journals (Sweden)

    Mirela Nichita

    2015-08-01

    Full Text Available The nowadays accounting information user profile became more sophisticated and the financial reports face new challenges in accomplishing process to meet users’ needs. The purpose of financial reports is to provide useful information to users. According to International Accounting Standards Board, the utility of information is defined through the qualitative characteristics (fundamental and enhancing. The financial crisis emphasized the limits of financial reporting who has been unable to prevent investors about the risks they were facing. Some managers expressed reservations about the quality and relevance of corporate reporting, stating that the annual report is no longer a useful tool. Due to the current changes in business environment, managers have been highly motivated to rethink and improve the risk governance philosophy, processes and methodologies. The lack of quality, timely data and adequate systems to capture, report and measure the right information across the organization is a fundamental challenge to implementing and sustaining all aspects of effective risk management. Starting from 80s, the investors became more interested in narratives (Notes to financial statements, than in primary reports (financial position and performance. Our research suggests a framework for risk reporting with the main goal of improving the good practice in risk management field. Also, we will debate the relation between the qualitative characteristics of accounting information, transparency and risk, and explore the possibility of developing some good practices in risk reporting.

  17. Irrigation water quality and the benefits of implementing good agricultural practices during tomato (Lycopersicum esculentum) production.

    Science.gov (United States)

    Estrada-Acosta, M; Jiménez, M; Chaidez, C; León-Félix, J; Castro-Del Campo, N

    2014-07-01

    The implementation of good agricultural practices (GAP) from irrigation water to the tomato packaging process enhances the safety of fresh produce and its value throughout the food chain. The aim of the present study was to show that fresh produce farms that apply and enforce GAP could reduce the presence of Salmonella in finished produce. Samples were collected biweekly from six packing houses from the central region of Sinaloa, México, for the isolation of Salmonella spp by the ISO 6579:2002 method, and the isolated strains were serotyped and genotyped by the Kauffmman-White scheme and pulsed field gel electrophoresis (PFGE), respectively. Salmonella strains were detected in 13 (36.1 %) irrigation water samples, while only two tomato samples were positive (5.5 %). Eight different serotypes were identified in irrigation water, and Salmonella Oranienburg (34 %) was the most prevalent; however, only Salmonella Agona and Salmonella Weltevreden were present on tomatoes. Salmonella Oranienburg was the most widely dispersed and variable serotype, with 10 different PFGE profiles. Salmonella Weltevreden was isolated from both types of samples, albeit with distinct genetic profiles, implying that the sources of contamination differ. These results confirm the utility of implementing good agricultural practices to reduce Salmonella contamination in irrigation water and the packaging process. PMID:24682661

  18. Proton irradiation effects on beryllium - A macroscopic assessment

    Science.gov (United States)

    Simos, Nikolaos; Elbakhshwan, Mohamed; Zhong, Zhong; Camino, Fernando

    2016-10-01

    Beryllium, due to its excellent neutron multiplication and moderation properties, in conjunction with its good thermal properties, is under consideration for use as plasma facing material in fusion reactors and as a very effective neutron reflector in fission reactors. While it is characterized by unique combination of structural, chemical, atomic number, and neutron absorption cross section it suffers, however, from irradiation generated transmutation gases such as helium and tritium which exhibit low solubility leading to supersaturation of the Be matrix and tend to precipitate into bubbles that coalesce and induce swelling and embrittlement thus degrading the metal and limiting its lifetime. Utilization of beryllium as a pion production low-Z target in high power proton accelerators has been sought both for its low Z and good thermal properties in an effort to mitigate thermos-mechanical shock that is expected to be induced under the multi-MW power demand. To assess irradiation-induced changes in the thermal and mechanical properties of Beryllium, a study focusing on proton irradiation damage effects has been undertaken using 200 MeV protons from the Brookhaven National Laboratory Linac and followed by a multi-faceted post-irradiation analysis that included the thermal and volumetric stability of irradiated beryllium, the stress-strain behavior and its ductility loss as a function of proton fluence and the effects of proton irradiation on the microstructure using synchrotron X-ray diffraction. The mimicking of high temperature irradiation of Beryllium via high temperature annealing schemes has been conducted as part of the post-irradiation study. This paper focuses on the thermal stability and mechanical property changes of the proton irradiated beryllium and presents results of the macroscopic property changes of Beryllium deduced from thermal and mechanical tests.

  19. RTE - Compliance with the code of good practices and Independence of RTE. 2013 Annual Report

    International Nuclear Information System (INIS)

    RTE Reseau de Transport d'Electricite (Electricity Transmission System Operator) is referred to in Article L111-40 of the French Energy Code as the company in charge of managing France's public electricity transmission grid. For this purpose, RTE must comply with all the rules and obligations that apply to transmission grid management companies as defined by the Energy Code. More particularly, the articles concerning the Transmission System Operators (TSOs) belonging to a Vertically Integrated Undertaking (VIU) apply to RTE, a wholly-owned subsidiary of Electricite de France. The purpose of these provisions is to establish and maintain over time the independence of the transmission grid operator vis-a-vis the VIU. The Commission de Regulation de l'Energie (CRE - Energy Regulation Board) certified RTE in its deliberation of January 26, 2012: To maintain this certification, RTE is required to comply with its commitments made within the framework of the certification process and maintain the conditions of independence that were approved by the CRE. Among the obligations that RTE is required to comply with as an independent transmission manager is the need to bring together 'in a code of good practices approved by the Energy Regulation Board, the organisational measures taken to prevent any risks of discriminatory practices in terms of access to the grid' (Article L111-22). RTE is also required to put in place 'a Compliance Officer in charge of ensuring [...] the conformity of its methods with the obligations of independence incumbent on it with regard to other companies belonging to the VIU', 'to verify the application [...] of the commitments appearing in the code of good practices' and to draw up an annual report [...] which it sends on to the Energy Regulating Board' on the subject (Article L111-34). This document is the report regarding compliance with the code of good practices for 2013 by the RTE Compliance Officer. It is destined for the CRE and is intended to

  20. Dynamic behaviour of S200F beryllium

    International Nuclear Information System (INIS)

    Compression tests have been made on a large scale of strain, strain rate (up to 2000 s-1) and temperature (between 20 C and 300 C). From these experiences, we have calculated a constitutive model for beryllium S200F, which can be used by computer codes. Its formulation is not far from Steinberg, Cochran and Guinan's. But in our case, the influences of temperature and strain rate appear clearly within the expression. To validate our equation, we have used it in a computer code. Its extrapolation for higher strain rates is in good agreement with experiments such as Taylor impact tests or plate impact tests (strain rates greater than 104 s-1). With micrography, we could settle a link between the main strain mode within the material, and the variation of one parameter of the model. Beside the constitutive model, we have shown that shock loaded beryllium behaves in two different ways. If the strain rate is lower than 5.106 s-1, then it is proportional to the squared shock pressure. Beyond, it is a linear function of shock pressure to the power of four. By a spall study on beryllium, we have confirmed that it is excessively fragile. Its fracture is sudden, at a strength near 1 GPa. (author)

  1. Estimation of beryllium ground state energy by Monte Carlo simulation

    Energy Technology Data Exchange (ETDEWEB)

    Kabir, K. M. Ariful [Department of Physical Sciences, School of Engineering and Computer Science, Independent University, Bangladesh (IUB) Dhaka (Bangladesh); Halder, Amal [Department of Mathematics, University of Dhaka Dhaka (Bangladesh)

    2015-05-15

    Quantum Monte Carlo method represent a powerful and broadly applicable computational tool for finding very accurate solution of the stationary Schrödinger equation for atoms, molecules, solids and a variety of model systems. Using variational Monte Carlo method we have calculated the ground state energy of the Beryllium atom. Our calculation are based on using a modified four parameters trial wave function which leads to good result comparing with the few parameters trial wave functions presented before. Based on random Numbers we can generate a large sample of electron locations to estimate the ground state energy of Beryllium. Our calculation gives good estimation for the ground state energy of the Beryllium atom comparing with the corresponding exact data.

  2. What Is "Good" Mentoring? Understanding Mentoring Practices of Teacher Induction through Case Studies of Finland and Australia

    Science.gov (United States)

    Pennanen, Matti; Bristol, Laurette; Wilkinson, Jane; Heikkinen, Hannu L. T.

    2016-01-01

    Mentoring is a practice widely utilised to support new teachers. However, in locally formed systems, the practice of mentoring is conditioned by traditions and arrangements specific to the site. To understand "good" mentoring, these local arrangements cannot be ignored. In this article, the theory of practice architectures is employed to…

  3. Self-assessment of safety culture in nuclear installations. Highlights and good practices

    International Nuclear Information System (INIS)

    This report summarizes the findings of two IAEA Technical Committee Meetings on Safety Culture Self-Assessment Highlights and Good Practices. The meetings took place on 3-5 June 1998 and 23-25 October 2000 in Vienna, and involved an international cross-section of representatives who participated both in plenary discussions and working groups. The purpose of the meetings was to discuss the practical implications of evolutionary changes in the development of safety culture, and to share international experience, particularly on the methods used for the assessment of safety culture and good practices for its enhancement in an organization. The working groups were allocated specific topics for discussion, which included the following: organizational factors influencing the implementation of actions to improve safety culture; how to measure, effectively, progress in implementing solutions to safety culture problems; the symptoms of a weakening safety culture; the suitability of different methods for assessing safety culture; the achievement of sustainable improvements in safety culture using the results of assessment; the potential threats to the continuation of a strong safety culture in an organization from the many challenges facing the nuclear industry. The working groups, when appropriate, considered issues from both the utility's and the regulator's perspectives. This report will be of interest to all organizations who wish to assess and achieve a strong and sustainable safety culture. This includes not only nuclear power plants, but also other sectors of the nuclear industry such as uranium mines and mills, nuclear fuel fabrication facilities, nuclear waste repositories, research reactors, accelerators, radiography facilities, etc. The report specifically supplements other IAEA publications on this subject

  4. Thermal fatigue of beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Deksnis, E.; Ciric, D.; Falter, H. [JET Joint undertaking, Abingdon (United Kingdom)] [and others

    1995-09-01

    Thermal fatigue life of S65c beryllium castellated to a geometry 6 x 6 x (8-10)mm deep has been tested for steady heat fluxes of 3 MW/m{sup 2} to 5 MW/m{sup 2} and under pulsed heat fluxes (10-20 MW/m{sup 2}) for which the time averaged heat flux is 5 MW/m{sup 2}. These tests were carried out in the JET neutral beam test facility A test sequence with peak surface temperatures {le} 600{degrees}C produced no visible fatigue cracks. In the second series of tests, with T{sub max} {le} 750{degrees}C evidence for fatigue appeared after a minimum of 1350 stress cycles. These fatigue data are discussed in view of the observed lack of thermal fatigue in JET plasma operations with beryllium PFC. JET experience with S65b and S65c is reviewed; recent operations with {Phi} = 25 MW/m{sup 2} and sustained melting/resolidification are also presented. The need for a failure criterion for finite element analyses of Be PFC lifetimes is discussed.

  5. A checklist for health research priority setting: nine common themes of good practice

    Directory of Open Access Journals (Sweden)

    Terry Robert F

    2010-12-01

    Full Text Available Abstract Health research priority setting processes assist researchers and policymakers in effectively targeting research that has the greatest potential public health benefit. Many different approaches to health research prioritization exist, but there is no agreement on what might constitute best practice. Moreover, because of the many different contexts for which priorities can be set, attempting to produce one best practice is in fact not appropriate, as the optimal approach varies per exercise. Therefore, following a literature review and an analysis of health research priority setting exercises that were organized or coordinated by the World Health Organization since 2005, we propose a checklist for health research priority setting that allows for informed choices on different approaches and outlines nine common themes of good practice. It is intended to provide generic assistance for planning health research prioritization processes. The checklist explains what needs to be clarified in order to establish the context for which priorities are set; it reviews available approaches to health research priority setting; it offers discussions on stakeholder participation and information gathering; it sets out options for use of criteria and different methods for deciding upon priorities; and it emphasizes the importance of well-planned implementation, evaluation and transparency.

  6. DOE handbook: Guide to good practices for the selection, training, and qualification of shift supervisors

    International Nuclear Information System (INIS)

    This Department of Energy (DOE) handbook is approved for use by all DOE Components and their contractors. The Handbook incorporates editorial changes to DOE-STD-1061-93, ''Guide to Good Practices for the Selection, Training, and Qualification of shift Supervisors,'' and supersedes DOE-STD-1061-93. Technical content of this Handbook has not changed from the original technical standard. Changes are primarily editorial improvements, redesignation of the standard to a Handbook, and format changes to conform with current Technical Standards Program procedures. This guide, used in conjunction with a facility-specific job analysis, provides a framework for the selection, training, qualification, and professional development of reactor facility and non-reactor nuclear facility shift supervisors. Training and qualification programs based on this guide should provide assurance that shift supervisors perform their jobs safely and competently

  7. The ESDP and Good Practices of Local Development in Peripheral Areas

    DEFF Research Database (Denmark)

    Gallina, Andrea; Capecchi, Vittorio

    Relocation of economic activities towards cheap labor cost countries, the enlargement of the EU and the difficulties of lagging regions in closing the gap with the wealthiest areas of Europe have called for a redefinition of regional development strategies and priorities at the EU level. The ESDP...... shows that the EU documents concerned with spatial planning and regional development suffer from a strong ambiguity in the choice of the development model (either neoliberal or solidaristic economy) both within Europe and in relation with Third countries. Through the analysis of selected good practices...... has provided a voluntary basis for European Member states to apply a polycentric approach to spatial and local economic development aiming to reduce the marginalization of peripheral and lagging areas. However, since 1999 the application of the ESDP has been controversial and an accurate analysis...

  8. Therapist Adherence to Good Psychiatric Practice in a Short-Term Treatment for Borderline Personality Disorder.

    Science.gov (United States)

    Kolly, Stéphane; Despland, Jean-Nicolas; de Roten, Yves; Marquet, Pierre; Kramer, Ueli

    2016-07-01

    Therapist adherence describes the quality of interventions according to the imperatives of a treatment model. We examined the relationship between therapist adherence and symptom change in the context of a short-term treatment with respect good psychiatric management (GPM) principles. Based on a parent trial, borderline personality disorder patients (N = 40) benefited from a 10-session intervention. Adherence to GPM was assessed using a GPM Adherence Scale (GPMAS). The psychometric properties of the GPMAS were excellent, and the adherence to GPM explained 16% of the general symptom improvement (t(1) = 2.38, β = 0.40, p = 0.02) and 23% of the borderline symptom improvement (t(1) = 2.46, β = 0.48, p = 0.02). Because GPM adherence predicts the outcome after only 10 sessions, GPMAS is a valuable measure early on in psychiatric practice as part of an initial step to longer-term treatment, to quickly detect problems and correct them. PMID:27187770

  9. Good manufacturing practice-compliant isolation and culture of human adipose derived stem cells

    Directory of Open Access Journals (Sweden)

    Phuc Van Pham

    2014-04-01

    Full Text Available Adipose-derived stem cells (ADSCs are excellent for regenerative medicine. Like mesenchymal stem cells, ADSCs possess multi-potent differentiation capacity that enables them to differentiate into osteoblasts, chondrocytes and adipocytes, as well as trans-differentiation into other cells. ADSC transplantation has gained attention in recent years, especially in vitro expanded ADSC transplantation. This study aimed to provide a new method to in vitro primarily culture and secondary culture of ADSCs that were compliant with good manufacturing practice for clinical applications. Stromal vascular fraction (SVF was extracted from adipose tissue by commercial kits. SVF was expanded in vitro in medium with non-allogeneic supplements. Cultured ADSCs maintained immune-phenotype, karyotype, and differentiation potential after ten passages. Moreover, ADSCs at 15th passage could not form tumors in NOD/SCID mice. This research produced a suitable protocol for clinical applications of expanded ADSCs. [Biomed Res Ther 2014; 1(4.000: 133-141

  10. DOE handbook: Guide to good practices for the selection, training, and qualification of shift supervisors

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    This Department of Energy (DOE) handbook is approved for use by all DOE Components and their contractors. The Handbook incorporates editorial changes to DOE-STD-1061-93, ``Guide to Good Practices for the Selection, Training, and Qualification of shift Supervisors,`` and supersedes DOE-STD-1061-93. Technical content of this Handbook has not changed from the original technical standard. Changes are primarily editorial improvements, redesignation of the standard to a Handbook, and format changes to conform with current Technical Standards Program procedures. This guide, used in conjunction with a facility-specific job analysis, provides a framework for the selection, training, qualification, and professional development of reactor facility and non-reactor nuclear facility shift supervisors. Training and qualification programs based on this guide should provide assurance that shift supervisors perform their jobs safely and competently.

  11. INNOVATIONS IN POLISH SOCIAL ECONOMY. GOOD PRACTICES CAFE-BOOKSTORE ''COOPERATIVE”

    Directory of Open Access Journals (Sweden)

    Piotr Krośniak

    2012-02-01

    Full Text Available The article is concentrating on the issue of the social economy and the presentation of good practice from Poland. For elaborating issues an example of the „Cooperative” was used. This is pioneering working on Polish scale which uses innovative actions for the counteraction of social exclusion. Brought up issues are alsoassociated with promotion of creating trilateral partnerships and development of the social franchise model. Presented model is the result of cooperation between UNDP Project Office in Poland, Municipal Centre for Social Services in Lublin represented by Local Activation Centre and Social Cooperative „The Four Seasons”.This innovative undertaking provides a new point of view at the social economy.

  12. Good manufacturing practice: manufacturing of a nerve agent antidote nanoparticle suspension.

    Science.gov (United States)

    Clark, Andrew P-Z; Dixon, Hong; Cantu, Norma L; Cabell, Larry A; McDonough, Joe A

    2013-01-01

    We have established a current good manufacturing practice (GMP) manufacturing process to produce a nanoparticle suspension of 1,1'-methylenebis-4-[(hydroxyimino)methyl]pyridinium dimethanesulfonate (MMB4 DMS) in cottonseed oil (CSO) as a nerve agent antidote for a Phase 1 clinical trial. Bis-pyridinium oximes such as MMB4 were previously developed for emergency treatment of organophosphate nerve agent intoxication. Many of these compounds offer efficacy superior to monopyridinium oximes, but they have poor thermal stability due to hydrolytic cleavage in aqueous solution. We previously developed a nonaqueous nanoparticle suspension to improve the hydrothermal stability, termed Enhanced Formulation (EF). An example of this formulation technology is a suspension of MMB4 DMS nanoparticles in CSO. Due to the profound effect of particle size distribution on product quality and performance, particle size must be controlled during the manufacturing process. Therefore, a particle size analysis method for MMB4 DMS in CSO was developed and validated to use in support of good laboratory practice/GMP development and production activities. Manufacturing of EF was accomplished by milling MMB4 DMS with CSO and zirconia beads in an agitator bead mill. The resulting bulk material was filled into 5-mL glass vials at a sterile fill facility and terminally sterilized by gamma irradiation. The clinical lot was tested and released, a Certificate of Analysis was issued, and a 3-year International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) stability study started. The drug product was placed in storage for Phase 1 clinical trial distribution. A dose delivery uniformity study was undertaken to ensure that the correct doses were delivered to the patients in the clinic. PMID:23929446

  13. Good manufacturing practice: manufacturing of a nerve agent antidote nanoparticle suspension.

    Science.gov (United States)

    Clark, Andrew P-Z; Dixon, Hong; Cantu, Norma L; Cabell, Larry A; McDonough, Joe A

    2013-01-01

    We have established a current good manufacturing practice (GMP) manufacturing process to produce a nanoparticle suspension of 1,1'-methylenebis-4-[(hydroxyimino)methyl]pyridinium dimethanesulfonate (MMB4 DMS) in cottonseed oil (CSO) as a nerve agent antidote for a Phase 1 clinical trial. Bis-pyridinium oximes such as MMB4 were previously developed for emergency treatment of organophosphate nerve agent intoxication. Many of these compounds offer efficacy superior to monopyridinium oximes, but they have poor thermal stability due to hydrolytic cleavage in aqueous solution. We previously developed a nonaqueous nanoparticle suspension to improve the hydrothermal stability, termed Enhanced Formulation (EF). An example of this formulation technology is a suspension of MMB4 DMS nanoparticles in CSO. Due to the profound effect of particle size distribution on product quality and performance, particle size must be controlled during the manufacturing process. Therefore, a particle size analysis method for MMB4 DMS in CSO was developed and validated to use in support of good laboratory practice/GMP development and production activities. Manufacturing of EF was accomplished by milling MMB4 DMS with CSO and zirconia beads in an agitator bead mill. The resulting bulk material was filled into 5-mL glass vials at a sterile fill facility and terminally sterilized by gamma irradiation. The clinical lot was tested and released, a Certificate of Analysis was issued, and a 3-year International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) stability study started. The drug product was placed in storage for Phase 1 clinical trial distribution. A dose delivery uniformity study was undertaken to ensure that the correct doses were delivered to the patients in the clinic.

  14. Competencies Influencing Extension Workers'Job Performance in Relation to the Good Agricultural Practices in Malaysia

    Directory of Open Access Journals (Sweden)

    Neda Tiraieyari

    2010-01-01

    Full Text Available Problem statement: The bottom line in agricultural trade is that manufacturers are demanding agricultural products that are produced in a sustainable way and with assurance that they are truly conforming to the standards of Good Agriculture Practice. Towards this objective, attention has been given on sustainable agricultural productions in Malaysia. This study is an attempt to investigate job performance of extension workers in terms of competency in relation to the Good Agricultural Practices. This research investigates the influence of competencies on extension workers’ job performance at the department of agriculture in Malaysia with the emphasis of having both human development competencies and technical competencies in order to perform extension job. Approach: Stratified random sampling technique employed to select 210 extension workers from the Department of Agriculture in four states of Malaysia. A structured research instrument was utilized to survey extension workers’ competency and job performance. To test the extent research data support the MLR model, Enter regression method was used. Results: Results showed that out of the nine competencies included in the regression model only four competencies contributed significantly in explaining the variation of job performance. The R2 value of 0.544 implies that the nine predictors explain about 54.4% of the variance in the extension workers' job performance. Conclusion/Recommendations: The findings suggest that the data dose not fully support the proposed nine-predictors multiple linear regression model. Finding was contrary to the expectations, since human development areas of competencies did not contribute to the job performance. Hence extension workers are not much involved in human development aspects of their job and they give primary attention to technology transfer rather than human development.

  15. Medication Errors: New EU Good Practice Guide on Risk Minimisation and Error Prevention.

    Science.gov (United States)

    Goedecke, Thomas; Ord, Kathryn; Newbould, Victoria; Brosch, Sabine; Arlett, Peter

    2016-06-01

    A medication error is an unintended failure in the drug treatment process that leads to, or has the potential to lead to, harm to the patient. Reducing the risk of medication errors is a shared responsibility between patients, healthcare professionals, regulators and the pharmaceutical industry at all levels of healthcare delivery. In 2015, the EU regulatory network released a two-part good practice guide on medication errors to support both the pharmaceutical industry and regulators in the implementation of the changes introduced with the EU pharmacovigilance legislation. These changes included a modification of the 'adverse reaction' definition to include events associated with medication errors, and the requirement for national competent authorities responsible for pharmacovigilance in EU Member States to collaborate and exchange information on medication errors resulting in harm with national patient safety organisations. To facilitate reporting and learning from medication errors, a clear distinction has been made in the guidance between medication errors resulting in adverse reactions, medication errors without harm, intercepted medication errors and potential errors. This distinction is supported by an enhanced MedDRA(®) terminology that allows for coding all stages of the medication use process where the error occurred in addition to any clinical consequences. To better understand the causes and contributing factors, individual case safety reports involving an error should be followed-up with the primary reporter to gather information relevant for the conduct of root cause analysis where this may be appropriate. Such reports should also be summarised in periodic safety update reports and addressed in risk management plans. Any risk minimisation and prevention strategy for medication errors should consider all stages of a medicinal product's life-cycle, particularly the main sources and types of medication errors during product development. This article

  16. Beryllium usage in fusion blankets and beryllium data needs

    International Nuclear Information System (INIS)

    Increasing numbers of designers are choosing beryllium for fusion reactor blankets because it, among all nonfissile materials, produces the highest number (2.5 neutron in an infinite media) of neutrons per 14-MeV incident neutron. In amounts of about 20 cm of equivalent solid density, it can be used to produce fissile material, to breed all the tritium consumed in ITER from outboard blankets only, and in designs to produce Co-60. The problem is that predictions of neutron multiplication in beryllium are off by some 10 to 20% and appear to be on the high side, which means that better multiplication measurements and numerical methods are needed. The n,2n reactions result in two helium atoms, which cause radiation damage in the form of hardening at low temperatures (300/degree/C). The usual way beryllium parts are made is by hot pressing the powder. A lower cost method is to cold press and then sinter. There is no radiation damage data on this form of beryllium. The issues of corrosion, safety relative to the release of the tritium built-up inside beryllium, and recycle of used beryllium are also discussed. 10 figs

  17. ADOPTION OF GOOD MANAGEMENT PRACTICE (GMP IN SMALL AND MEDIUM SCALE VANNAMEI SHRIMP FARMS ON THE NORTHERN SHORE EAST JAVA

    Directory of Open Access Journals (Sweden)

    Paula Florina

    2012-09-01

    Full Text Available The objectives of this research were to describe the value chain of Vannamei shrimp industry on the northern shore of East Java, to identify the current management practice that is being implemented by small to medium scale shrimp farmers, to analyze the level of adoption of Good Management Practice by small to medium scale shrimp farmers and to identify the challenges that prevent small to medium scale farmers from adopting Good Management Practice. This research utilized descriptive qualitative method using multiple-case study. Data collection was conducted through interviews with experts and various actors in shrimp industry and interviews and observations in shrimp farms. From this research it can be concluded that the farming activity gives the largest contribution in final product value, that the current management practice in observed intensive Vannamei shrimp farms is in line with recommendations of various institutions with the exception of waste management, that the observed intensive Vannamei shrimp farms have high adoption level of Good Management Practice (GMP for various stages of shrimp farming activity with the exception of waste management, and that there is a tendency that farmers follow the good practices that have direct impact to the success of the production, and that the main challenges of GMP adoption are the lack of a comprehensive GMP manual, the lack of structured technology dissemination, and the lack of incentive for the farmers to adopt waste management practices.Keywords: Litopenaeus Vannamei, Shrimp Farm, Good Management Practice, Value Chain, Multiple-Case Study

  18. Good clinical practice guidelines for care home residents with diabetes: an executive summary.

    Science.gov (United States)

    Sinclair, A J

    2011-07-01

    A Task and Finish Group of Diabetes UK was convened over 14 months to undertake a systematic review of the original 1999 British Diabetic Association guidance on care home diabetes, incorporate new research findings and produce a set of recommendations that are evidenced-based, practical and implementable within UK care home settings. The anticipation of Diabetes UK is that these guidelines will represent a national policy of good clinical practice for diabetes care within care homes. This executive summary demonstrates how the full guidelines should provide a framework of assessment of the quality of diabetes care within care homes, for use by regulatory bodies who have responsibility for this provision of diabetes care. This document is primarily based on recommendations for adults living within British care home environments and its focus, by virtue of the nature and characteristics of residents, is on older adults. Improvements in diabetes care within residential and nursing homes are likely to follow a sustained commitment by health and social care professionals to ensure that the well-being of residents with diabetes is paramount, that high-quality policies of diabetes care are implemented and monitored and effective diabetes education is a mandatory and integral part of care home staff training. PMID:21672001

  19. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols.

    Science.gov (United States)

    Karumbayaram, Saravanan; Lee, Peiyee; Azghadi, Soheila F; Cooper, Aaron R; Patterson, Michaela; Kohn, Donald B; Pyle, April; Clark, Amander; Byrne, James; Zack, Jerome A; Plath, Kathrin; Lowry, William E

    2012-01-01

    The clinical application of human-induced pluripotent stem cells (hiPSCs) requires not only the production of Good Manufacturing Practice-grade (GMP-grade) hiPSCs but also the derivation of specified cell types for transplantation under GMP conditions. Previous reports have suggested that hiPSCs can be produced in the absence of animal-derived reagents (xenobiotics) to ease the transition to production under GMP standards. However, to facilitate the use of hiPSCs in cell-based therapeutics, their progeny should be produced not only in the absence of xenobiotics but also under GMP conditions requiring extensive standardization of protocols, documentation, and reproducibility of methods and product. Here, we present a successful framework to produce GMP-grade derivatives of hiPSCs that are free of xenobiotic exposure from the collection of patient fibroblasts, through reprogramming, maintenance of hiPSCs, identification of reprogramming vector integration sites (nrLAM-PCR), and finally specification and terminal differentiation of clinically relevant cells. Furthermore, we developed a primary set of Standard Operating Procedures for the GMP-grade derivation and differentiation of these cells as a resource to facilitate widespread adoption of these practices.

  20. The Document of the Americas: Good Clinical Practices for Regulatory Authorities

    Directory of Open Access Journals (Sweden)

    Ricardo Palacios

    2009-12-01

    Full Text Available In 1996, when the Guidelines for Good Clinical Practices of the International Conference on Harmonization (ICH were adopted, they sought to facilitate the actions of regulatory authorities over the different players of clinical research. These guidelines were created and incorporated to the legislation of the three regions of the world (United States, European Union, and Japan where most of the drugs, vaccines, biologicals, diagnostic tests, and medical devices are produced. The regulatory authorities from those three regions are characterized for their extensive technical capacity to execute their mission of promoting technological advances and protecting communities. However, undertaking this task has been difficult, partially because the ICH Good Clinical Practices defined responsibilities for Ethical Committees, Sponsors, and Investigators; but the regulatory authorities did not precise their own responsibilities or indicate how they would accomplish their duties in that document and, therefore, did not reach the harmonization of their practices in those subjects. Certainly, this point is one of the major advances offered by the Document of the Americas on Good Clinical Practices: helping the regulatory authorities of the continent to establish a common platform on how to perform their duties regarding clinical research. The possibilities that this common regulatory methodology offers to the authorities from our countries, with greater limitations in budget and in human resources than their ICH counterparts, are promising: it might allow unified staff training, conduction of joint inspections and, even, thinking of a mutual recognition for the actions of the authorities in each country, as occurred in Europe more than three decades ago. However, the promises have not been delivered in the desired extension: despite the March 2005 meeting held in the Dominican Republic, where the Document of the Americas was published, was held in March, 2005

  1. Development and implementation of the Good Neighbor Agreement (GNA) practice in the USA sustainable mining development.

    Science.gov (United States)

    Masaitis, Alexandra

    2014-05-01

    New economic, environmental and social challenges for the mining industry in the USA show the need to implement "responsible" mining practices that include improved community involvement. Conflicts which occur in the US territory and with US mining companies around the world are now common between the mining proponents, NGO's and communities. These conflicts can sometimes be alleviated by early development of modes of communication, and a formal discussion format that allows airing of concerns and potential resolution of problems. One of the methods that can formalize this process is to establish a Good Neighbor Agreement (GNA), which deals specifically with challenges in relationships between mining operations and the local communities. It is a new practice related to mining operations that are oriented toward social needs and concerns of local communities that arise during the normal life of a mine, which can achieve sustainable mining practices. The GNA project being currently developed at the University of Nevada, USA in cooperation with the Newmont Mining Corporation has a goal of creating an open company/community dialog that will help identify and address sociological and environmental concerns associated with mining. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Identify spheres of possible cooperation between mining companies, government organizations, and NGO's. 2. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry's accountability and provide higher levels of confidence for the community that a mine is operated in a safe and sustainable manner. Implementation of the GNA can help identify and evaluate conflict criteria in mining/community relationships; determine the status of concerns; determine the role and responsibilities of stakeholders; analyze problem resolution feasibility; maintain the community

  2. Good practices of interdisciplinary international cooperation between universities and local development on social suffering in urban spaces

    OpenAIRE

    2014-01-01

    This article describes areas of application of good practices which emerged from international and interdisciplinary research on social suffering in urban spaces and on change agentry with intercultural sensitivity, which is at the basis of a new concept of co-operation for local development. Three examples of possible good practices are illustrated: 1) Pilot action-research project by UNAN of Managua on community health and quality of the life in Managua’s Barrio Carlos Fonseca, a urban plac...

  3. Monte Carlo uncertainty analyses for integral beryllium experiments

    CERN Document Server

    Fischer, U; Tsige-Tamirat, H

    2000-01-01

    The novel Monte Carlo technique for calculating point detector sensitivities has been applied to two representative beryllium transmission experiments with the objective to investigate the sensitivity of important responses such as the neutron multiplication and to assess the related uncertainties due to the underlying cross-section data uncertainties. As an important result, it has been revealed that the neutron multiplication power of beryllium can be predicted with good accuracy using state-of-the-art nuclear data evaluations. Severe discrepancies do exist for the spectral neutron flux distribution that would transmit into significant uncertainties of the calculated neutron spectra and of the nuclear blanket performance in blanket design calculations. With regard to this, it is suggested to re-analyse the secondary energy and angle distribution data of beryllium by means of Monte Carlo based sensitivity and uncertainty calculations. Related code development work is underway.

  4. Beryllium technology workshop, Clearwater Beach, Florida, November 20, 1991

    International Nuclear Information System (INIS)

    This report discusses the following topics: beryllium in the ITER blanket; mechanical testing of irradiated beryllium; tritium release measurements on irradiated beryllium; beryllium needs for plasma-facing components; thermal conductivity of plasma sprayed beryllium; beryllium research at the INEL; Japanese beryllium research activities for in-pile mockup tests on ITER; a study of beryllium bonding of copper alloy; new production technologies; thermophysical properties of a new ingot metallurgy beryllium product line; implications of beryllium:steam interactions in fusion reactors; and a test program for irradiation embrittlement of beryllium at JET

  5. The procurement of cells for the derivation of human embryonic stem cell lines for therapeutic use: recommendations for good practice.

    Science.gov (United States)

    Murdoch, Alison; Braude, Peter; Courtney, Aidan; Brison, Daniel; Hunt, Charles; Lawford-Davies, James; Moore, Harry; Stacey, Glyn; Sethe, Sebastian

    2012-03-01

    The donation of human embryos for the derivation of embryonic stem cell lines that may be used in the development of therapeutic products raises more complex ethical, practical and regulatory problems than the donation of embryos for non-clinical research. This review considers these issues and offers recommendations for good practice.

  6. Preferences of people living with diabetes for the aspects of good pharmaceutical practice

    Directory of Open Access Journals (Sweden)

    Danyliv, Andriy

    2012-07-01

    Full Text Available BACKGROUND: People living with diabetes (PLD have special needs which could be effectively and efficiently addressed at the stage of pharmaceutical care. We analyzed preferences of PLD in Kyiv for services that could be potentially implemented in a specialized pharmacy.METHODS: We used a discrete choice experiment (DCE to elicit preferences for pharmacist’s consultation, possibility of testing, and the availability of special products. The pharmacy was described with 3 attributes having 2 levels and 2 attributes having 3 levels. The analysis is based on interviews with 98 PLD. Respondents were recruited either in the in-patient unit of Kyiv endocrinology center or through snow-ball approach between January 2012 and March 2012. The DCE part consisted of 12 choice tasks (orthogonal fractional factorial design. To reduce the number of choices per respondent, the DCE was split into two experiments of 6 choices each. Respondents were randomly assigned to either DCE. Logistic regression xtlogit was used to model DCE responses using STATA version 11.0. RESULTS: Pharmacist’s consultation regarding the use of drugs, their compatibility, and special diet was the most important choice factor among PLD (marginal willingness to pay (MWTP was 23.38 UAH, followed by the possibility of controlling the blood pressure, blood sugar and cholesterol levels, (MWTP is 21.68 UAH and the availability of specialized products (MWTP is 13.57 UAH. Time for purchase (including travel and waiting did not significantly affect the choice of pharmacy.CONCLUSIONS: Respondents gave mostly meaningful answers to the DCE and the model is theoretically valid. PLD are willing to spend time on traveling to the specialized pharmacy with Good Pharmacy Practice GPP services. Conclusively, introduction of the pharmacy with special focus on PLD has good potential in Kyiv as they are ready to spend additional time and money to obtain proper services.

  7. Good Practices in Educating and Informing the New Generation of Consumers on Organic Foodstuffs

    Directory of Open Access Journals (Sweden)

    Lelia Voinea

    2015-02-01

    good practices guideline in education and consumer information in order to acquire the skills for a more correct buying decision. We believe that these good practices should be included among the pursuits of the education system, government structures and specialized NGOs.

  8. Medication Errors: New EU Good Practice Guide on Risk Minimisation and Error Prevention.

    Science.gov (United States)

    Goedecke, Thomas; Ord, Kathryn; Newbould, Victoria; Brosch, Sabine; Arlett, Peter

    2016-06-01

    A medication error is an unintended failure in the drug treatment process that leads to, or has the potential to lead to, harm to the patient. Reducing the risk of medication errors is a shared responsibility between patients, healthcare professionals, regulators and the pharmaceutical industry at all levels of healthcare delivery. In 2015, the EU regulatory network released a two-part good practice guide on medication errors to support both the pharmaceutical industry and regulators in the implementation of the changes introduced with the EU pharmacovigilance legislation. These changes included a modification of the 'adverse reaction' definition to include events associated with medication errors, and the requirement for national competent authorities responsible for pharmacovigilance in EU Member States to collaborate and exchange information on medication errors resulting in harm with national patient safety organisations. To facilitate reporting and learning from medication errors, a clear distinction has been made in the guidance between medication errors resulting in adverse reactions, medication errors without harm, intercepted medication errors and potential errors. This distinction is supported by an enhanced MedDRA(®) terminology that allows for coding all stages of the medication use process where the error occurred in addition to any clinical consequences. To better understand the causes and contributing factors, individual case safety reports involving an error should be followed-up with the primary reporter to gather information relevant for the conduct of root cause analysis where this may be appropriate. Such reports should also be summarised in periodic safety update reports and addressed in risk management plans. Any risk minimisation and prevention strategy for medication errors should consider all stages of a medicinal product's life-cycle, particularly the main sources and types of medication errors during product development. This article

  9. The Effects of Good Breeding Practices on Brucellosis Incidence in Kangal Akkaraman Sheep Flocks

    Directory of Open Access Journals (Sweden)

    Yusuf Ziya Oğrak

    2014-03-01

    Full Text Available The aim of the present study was to compare the incidence of brucellosis in groups of Kangal Akkaraman sheep flocks raised in farm conditions in Sivas province. The first and second groups of the sheep flocks were part of the 8 sub-projects which belong to The Project entitled “Nationwide Genetic Improvement of Small Ruminants in Farm Condition” continued for 7 and 1-3 years, respectively. The third group of the sheep flocks was not part of this nationwide project. The study material consisted of 1491 units of blood serum (n=278, 1166 and 47 for the first, second and third groups, respectively. Brucella antibodies were looked for in blood serum using tube and slide agglutination tests. The incidences of brucellosis were 4% and 7.5% in flocks which were part of the nationwide project continued for 7 and 3 years, respectively and 25.5% for the flocks not part of the nationwide project. The differences between groups were found statistically significant. Even though there was no brucella vaccination programs in the flocks of the nationwide project, practices such as regular controls of the flocks by veterinary technicians, drug/vaccination applications for parasites and some other diseases, removal of rams positive for brucella before breeding season significantly reduced the incidence of brucella. As a result, promoting good breeding practices along with the brucella vaccination program applied by the related Ministry can be very beneficial for the eradication of brucella disease that is a big problem for the country.

  10. TEACHING AND LEARNING WITH TECHNOLOGY: A THEORETICAL MODEL FOR GOOD EDUCATIONAL PRACTICES WITH ICT

    Directory of Open Access Journals (Sweden)

    Jesús Valverde Berrocoso

    2010-02-01

    Full Text Available This article aims to define a theoretical explanatory framework for the integration of information technologies and communication technologies (ICT in education from the perspective of teacher education. The initial and continuing training of teachers is characterized by a tendency towards "essentialisation" of technology and generation of users who do not usually think about educational uses of technology in their own contexts. Our research on the integration of ICT in the classroom has allowed us to observe the lack of connection between the personal and professional use of teachers of these technological tools, as well as the need for training is geared towards developing skills and knowledge to examine, in a critical manner, the educational implications of these new teaching aids. This article is based on the proposed Koehler & Mishra (2005, 2006, 2007 and 2008 called TPCK (Technological Pedagogical Content Knowledge which is based on the construct of PCK Shulman (1987 to which is added the concept of "Technology" (T to those of "Pedagogy" (P and "Curriculum Content" (C. Connections and dynamic interactions between these three key components leading to different components to be considered in understanding the processes of integration of ICT in schools. Good educational practices with ICT are multidimensional and complex actions that require (1 understand the representation and formulation of concepts and procedures for their understanding through ICT, (2 develop constructivist teaching strategies that use ICT for teaching content curriculum, (3 know the difficulties in learning concepts and how ICT can help overcome them, and (4 knowing the students' prior knowledge and the epistemology of the curriculum to understand how ICT can be used to build on pre-existing knowledge and develop new epistemologies. These skills clearly go beyond the isolation that has an expert in a curriculum (teacher of a discipline, an expert in IT (engineer, or an

  11. [Psychometric properties of an instrument to evaluate the nurse attitude towards good practice guides].

    Science.gov (United States)

    López-Díaz, Cristina; Fraille-Calle, Luis; Herrero-Rosado, Marta; Arnés-Muñoz, Vanessa; De-Dios-De-Dios, Teresa

    2016-01-01

    The Guides of Good Practices (GGP) are necessary tools in the universal healthcare and in the clinical management, providing the user/patient with a major quality in the assistance, in order to optimize and reinforce an individualized attention into action, taking into account the best scientific evidence. The literature provides different references to the development of the GGP, but there is little knowledge about the attitude of professionals towards them, since most of the studies that exist are qualitative. Therefore, the aim of this work is to construct and validate a Likert scale which could assess the attitude of the nurse towards GGP. The methodology used was quantitative, descriptive, cross, opinion, anonymous and also it could validate a scale via the following measurements: content validation by experts, correlation between items, external reliability, internal consistency, stability and exploratory factor analysis. The result was a scale consisting of 20 items that refer to the attitude toward the GGP, with a percentage of agreement among experts over 75 % on all the items, and a significant Pearson correlation between the pre-test and post-test in all variables, but for three. The internal consistency measured by Cronbach's alpha was 0.878. These results are acceptable in terms of the psychometric characteristics of the instrument, with easy and fast administration and simple in their interpretation, allowing quantifying and generating knowledge about the attitudes of nurses towards GGP. PMID:26996039

  12. Good manufacturing practice: the role of local manufacturers and competent authorities.

    Science.gov (United States)

    Tomić, Siniša; Filipović Sučić, Anita; Ilić Martinac, Adrijana

    2010-12-01

    In every country, a manufacturer of medicinal products for either human or veterinary use is required to operate in compliance with local legislation. In all EU Member States, legislation is approximated to the effect that they are committed to abide by the same standards. The candidate countries transpose the acquis into their national legislation, including the good manufacturing practice (GMP). Consequently, the local manufacturer is required to strictly comply with GMP and the manufacturing licence, including for medicinal products exclusively intended for export. A vital role is also played by national regulatory authorities, in Croatia by the Agency for Medicinal Products and Medical Devices which issues the manufacturing licence, GMP certificate, and the Certificate of a Pharmaceutical Product (CPP) and conducts laboratory control of products. GMP inspection is carried out by the Pharmaceutical Inspectorate with the Ministry of Health and Social Welfare. Both authorities are responsible only for human medicines. There are legislative issues not yet harmonised with the acquis, but as a country aspiring for the EU membership, Croatia is expected to demonstrate that its industry and competent authorities are able to conform to current requirements and thus fully adhere to the integrated European regulatory network. Hence the importance of strengthening the institutional capacity of the competent authorities, as insufficient resources may have a direct bearing on patients by limiting their access to affordable treatment.

  13. Guide to good practices for the design, development, and implementation of examinations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The purpose of this Guide to Good Practices is to provide direction to training personnel in the broad areas of design, development, and implementation of examinations. Nuclear facilities spend a significant amount of training resources testing trainees. Tests are used for employee selection, qualification, requalification, certification and recertification, and promotion. Ineffective testing procedures, or inappropriate interpretation of test results, can have significant effects on both human performance and facility operations. Test development requires unique skills, and as with any skill, training and experience are needed to develop the skills. Test development, test use, test result interpretation, and test refinement, like all other aspects of the systematic approach to training, should be part of an ongoing, systematic process. For some users this document will provide a review of ideas and principles with which they are already familiar; for others it will present new concepts. While not intended to provide in-depth coverage of test theory design and development, it should provide developers, instructors, and evaluators with a foundation on which to develop sound examinations.

  14. Good Practice Policy Framework for Energy Technology Research Development and Demonstration (RD and D)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The transition to a low carbon economy clearly requires accelerating energy innovation and technology adoption. Governments have an important role in this context. They can help by establishing the enabling environment in which innovation can thrive, and within which effective and efficient policies can be identified, with the specific goal of advancing research, development, demonstration and, ultimately, deployment (RDD&D) of clean energy technologies. At the front end of the innovation process, significant increases in, and restructuring of, global RD&D efforts will be required, combined with well-targeted government RD&D policies. The development of a clear policy framework for energy technology RD&D, based on good practices, should include six elements: Coherent energy RD&D strategy and priorities; Adequate government RD&D funding and policy support; Co-ordinated energy RD&D governance; Strong collaborative approach, engaging industry through public private partnerships (PPPs); Effective RD&D monitoring and evaluation; and Strategic international collaboration. While countries have been favouring certain technologies over others, based on decisions on which areas are to receive funding, clear priorities are not always determined through structured analysis and documented processes. A review of stated energy RD&D priorities, based on announced technology programmes and strategies, and recent spending trends reveals some important deviations from stated priorities and actual RD&D funding.

  15. THE INTEGRATION OF IMMIGRANT CHILDREN IN SLOVENIA: GOOD PRACTICES FROM PRIMARY SCHOOLS

    Directory of Open Access Journals (Sweden)

    Marijanca Ajša VIŽINTIN

    2013-05-01

    Full Text Available European society has always been and still is diverse in many aspects, including language, ethnicity, culture, religion and economics. We may thus speak of diversity both within individual countries and among countries – and also within school classrooms. Immigrant children who enrol in the Slovenian school system come to Slovenia primarily because of the family reunion. This paper sets out four examples of good practices (two urban and two rural schools, where various support systems were developed for the successful integration of immigrant children. The integration of immigrant children has been a success at those schools that are familiar with the possibilities under the law and European guidelines for integration of immigrant children, that seek a variety of ways to cooperate with parents, those schools where teachers take regular and additional training, develop their own intercultural competence and collaborate on a variety of projects. The results are even better if the school has support on the local level, and if intercultural competence is developed among all inhabitants.

  16. Guide to good practices for the selection, training, and qualification of shift technical advisors

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-02-01

    The DOE Guide to Good Practices For the Selection, Training, and Qualification of Shift Technical Advisors can be used by any DOE nuclear facility that has implemented the shift technical advisor (STA) position. DOE Order 5480.20A, Personnel Selection, Qualification and Training Requirements for DOE Nuclear Facilities, states that only Category A reactors must have a shift technical advisor. However, many DOE nuclear facilities have implemented the shift technical advisor position to provide independent on-shift technical advice and counsel to the shift operating personnel to help determine cause and mitigation of facility accidents. Those DOE nuclear facilities that have implemented or are going to implement the shift technical advisor position will find this guide useful. This guide addresses areas that may be covered by other training programs. In these cases, it is unnecessary (and undesirable) to duplicate these areas in the STA training program as long as the specific skills and knowledge essential for STAs are addressed. The guide is based on the premise that the trainee has not completed any facility-specific training other than general employee training.

  17. Guide to good practices for the selection, training, and qualification of shift technical advisors

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-01

    The DOE Guide to Good Practices For The Selection, Training, and Qualification of Shift Technical Advisors can be used by any DOE nuclear facility that has implemented the shift technical advisor position. DOE Order 5480-20, ``Personnel Selection, Qualification, Training, and Staffing Requirements at DOE Reactor and Non-Reactor Nuclear Facilities,`` states that only Category A reactors must use shift technical advisor position. However, many DOE nuclear facilities have implemented the shift technical advisor position to provide independent on-shift technical advice and counsel to the shift operating personnel to help determine cause and mitigation of facility accidents. Those DOE nuclear facilities that have implemented or are going to implement the shift technical advisor position will find this guide useful. This guide addresses areas that may be covered by other training programs. In these cases, it is unnecessary (and undesirable) to duplicate these areas in the STA training program as long as the specific skills and knowledge essential for STAs are addressed. The guide is presented based on the premise that the trainee has not completed any facility-specific training other than general employee training.

  18. Production of mesenchymal stromal/stem cells according to good manufacturing practices: a review.

    Science.gov (United States)

    Sensebé, Luc; Gadelorge, Mélanie; Fleury-Cappellesso, Sandrine

    2013-06-07

    Because of their multi/pluripotency and immunosuppressive properties, mesenchymal stem/stromal cells (MSCs) are important tools for treating immune disorders and for tissue repair. The increasing use of MSCs, their definition as advanced-therapy medicinal products in European regulations, and the US Food and Drug Administration requirements for their production and use imply the use of production processes that should be in accordance with Good Manufacturing Practices (GMPs). Complying with GMPs requires precisely defining the production process (es) as well as the multiple criteria required for a quality final product. Such variables include the environment, staff training and qualification, and controls. Developing processes based on well-defined or completely defined media and operating in closed systems or bioreactors is important and will increase safety and reproducibility. One of the most challenging issues remains implementation of relevant and reproducible controls for safety and efficacy. A linking of researchers, research and development teams, producers, and clinicians is mandatory to achieve GMP-compliant processes with relevant controls for producing well-defined, safe, and efficient MSCs.

  19. Current good manufacturing practice in plant automation of biological production processes.

    Science.gov (United States)

    Dorresteijn, R C; Wieten, G; van Santen, P T; Philippi, M C; de Gooijer, C D; Tramper, J; Beuvery, E C

    1997-01-01

    The production of biologicals is subject to strict governmental regulations. These are drawn up in current good manufacturing practices (cGMP), a.o. by the U.S. Food and Drug Administration. To implement cGMP in a production facility, plant automation becomes an essential tool. For this purpose Manufacturing Execution Systems (MES) have been developed that control all operations inside a production facility. The introduction of these recipe-driven control systems that follow ISA S88 standards for batch processes has made it possible to implement cGMP regulations in the control strategy of biological production processes. Next to this, an MES offers additional features such as stock management, planning and routing tools, process-dependent control, implementation of software sensors and predictive models, application of historical data and on-line statistical techniques for trend analysis and detection of instrumentation failures. This paper focuses on the development of new production strategies in which cGMP guidelines are an essential part.

  20. DOE handbook: Guide to good practices for training and qualification of maintenance personnel

    International Nuclear Information System (INIS)

    The purpose of this Handbook is to provide contractor training organizations with information that can be used to verify the adequacy of and/or modify existing maintenance training programs, or to develop new training programs. This guide, used in conjunction with facility-specific job analyses, provides a framework for training and qualification programs for maintenance personnel at DOE reactor and nonreactor nuclear facilities. Recommendations for qualification are made in four areas: education, experience, physical attributes, and training. The functional positions of maintenance mechanic, electrician, and instrumentation and control technician are covered by this guide. Sufficient common knowledge and skills were found to include the three disciplines in one guide to good practices. Contents include: qualifications; on-the-job training; trainee evaluation; continuing training; training effectiveness evaluation; and program records. Appendices are included which relate to: administrative training; industrial safety training; fundamentals training; tools and equipment training; facility systems and component knowledge training; facility systems and component skills training; and specialized skills training

  1. [Ecological agriculture: future of Good Agriculture Practice of Chinese materia medica].

    Science.gov (United States)

    Guo, Lan-ping; Zhou, Liang-yun; Mo, Ge; Wang, Sheng; Huang, Lu-qi

    2015-09-01

    Based on the ecological and economic problems in Good Agriculture Practice (GAP) of Chinese material medica, we introduced the origin, concept, features and operative technology of eco-agriculture worldwide, emphasizing its modes on different biological levels of landscape, ecosystem, community, population, individual and gene in China. And on this basis, we analyzed the background and current situation of eco-agriculture of Chinese materia medica, and proposed its development ideas and key tasks, including: (1) Analysis and planning of the production pattern of Chinese material medica national wide. (2) Typical features extraction of regional agriculture of Chinese materia medica. (3) Investigation of the interaction and its mechanism between typical Chinese materia medica in each region and the micro-ecology of rhizosphere soil. (4) Study on technology of eco-agriculture of Chinese materia medica. (5) Extraction and solidification of eco-agriculture modes of Chinese materia medica. (6) Study on the theory of eco-agriculture of Chinese materia medica. Also we pointed out that GAP and eco-agriculture of Chinese material medica are both different and relative, but they are not contradictory with their own features. It is an irresistible trend to promote eco-agriculture in the GAP of Chinese material medica and coordinate ecological and economic development.

  2. Beryllium Related Matter

    Energy Technology Data Exchange (ETDEWEB)

    Gaylord, R F

    2008-12-23

    In recent months, LLNL has identified, commenced, and implemented a series of interim controls, compensatory measures, and initiatives to ensure worker safety, and improve safety processes with regards to potential worker exposure to beryllium. Many of these actions have been undertaken in response to the NNSA Independent Review (COR-TS-5/15/2008-8550) received by LLNL in November of 2008. Others are the result of recent discoveries, events or incidents, and lessons learned, or were scheduled corrective actions from earlier commitments. Many of these actions are very recent in nature, or are still in progress, and vary in the formality of implementation. Actions are being reviewed for effectiveness as they progress. The documentation of implementation, and review of effectiveness, when appropriate, of these actions will be addressed as part of the formal Corrective Action Plan addressing the Independent Review. The mitigating actions taken fall into the following categories: (1) Responses to specific events/concerns; (2) Development of interim controls; (3) Review of ongoing activities; and (4) Performance improvement measures.

  3. [Qualitative evaluation of employer requirements associated with occupational health and safety as good practice in small-scale enterprises].

    Science.gov (United States)

    Kuroki, Naomi; Miyashita, Nana; Hino, Yoshiyuki; Kayashima, Kotaro; Fujino, Yoshihisa; Takada, Mikio; Nagata, Tomohisa; Yamataki, Hajime; Sakuragi, Sonoko; Kan, Hirohiko; Morita, Tetsuya; Ito, Akiyoshi; Mori, Koji

    2009-09-01

    The purpose of this study was to identify what motivates employers to promote good occupational health and safety practices in small-scale enterprises. Previous studies have shown that small-scale enterprises generally pay insufficient attention to issues of occupational health and safety. These findings were mainly derived from questionnaire based surveys. Nevertheless, some small-scale enterprises in which employers exercise good leadership do take a progressive approach to occupational health and safety. Although good practices can be identified in small-scale enterprises, it remains unclear what motivates employers in small-scale enterprises to actively implement occupational health and safety practices. We speculated that identifying employer motivations in promoting occupational health would help to spread good practices among small-scale enterprises. Using a qualitative approach based on the KJ methods, we interviewed ten employers who actively promote occupational health and safety in the workplace. The employers were asked to discuss their views of occupational health and safety in their own words. A semi-structured interview format was used, and transcripts were made of the interviews. Each transcript was independently coded by two or more researchers. These transcripts and codes were integrated and then the research group members discussed the heading titles and structural relationships between them according to the KJ method. Qualitative analysis revealed that all the employers expressed a strong interest in a "good company" and "good management". They emphasized four elements of "good management", namely "securing human resources", "trust of business partners", "social responsibility" and "employer's health condition itself", and considered that addressing occupational health and safety was essential to the achievement of these four elements. Consistent with previous findings, the results showed that implementation of occupational health and safety

  4. Processing Irradiated Beryllium For Disposal

    Energy Technology Data Exchange (ETDEWEB)

    T. J. Tranter; R. D. Tillotson; N. R. Mann; G. R. Longhurst

    2005-11-01

    The purpose of this research was to develop a process for decontaminating irradiated beryllium that will allow it to be disposed of through normal radwaste channels. Thus, the primary objectives of this ongoing study are to remove the transuranic (TRU) isotopes to less than 100 nCi/g and remove {sup 60}Co, and {sup 137}Cs, to levels that will allow the beryllium to be contact handled. One possible approach that appears to have the most promise is aqueous dissolution and separation of the isotopes by selected solvent extraction followed by precipitation, resulting in a granular form for the beryllium that may be fixed to prevent it from becoming respirable and therefore hazardous. Beryllium metal was dissolved in nitric and fluorboric acids. Isotopes of {sup 241}Am, {sup 239}Pu, {sup 85}Sr, and {sup 137}Cs were then added to make a surrogate beryllium waste solution. A series of batch contacts was performed with the spiked simulant using chlorinated cobalt dicarbollide (CCD) and polyethylene glycol diluted with sulfone to extract the isotopes of Cs and Sr. Another series of batch contacts was performed using a combination of octyl (phenyl)-N,N-diisobutylcarbamoylmethylphosphine oxide (CMPO) in tributyl phosphate (TBP) diluted with dodecane for extracting the isotopes of Pu and Am. The results indicate that greater than 99.9% removal can be achieved for each isotope with only three contact stages.

  5. Are pediatric Open Access journals promoting good publication practice? An analysis of author instructions

    Directory of Open Access Journals (Sweden)

    Wolff Robert F

    2011-04-01

    Full Text Available Abstract Background Several studies analyzed whether conventional journals in general medicine or specialties such as pediatrics endorse recommendations aiming to improve publication practice. Despite evidence showing benefits of these recommendations, the proportion of endorsing journals has been moderate to low and varied considerably for different recommendations. About half of pediatric journals indexed in the Journal Citation Report referred to the Uniform Requirements for Manuscripts of the International Committee of Medical Journal Editors (ICMJE but only about a quarter recommended registration of trials. We aimed to investigate to what extent pediatric open-access (OA journals endorse these recommendations. We hypothesized that a high proportion of these journals have adopted recommendations on good publication practice since OA electronic publishing has been associated with a number of editorial innovations aiming at improved access and transparency. Methods We identified 41 journals publishing original research in the subject category "Health Sciences, Medicine (General, Pediatrics" of the Directory of Open Access Journals http://www.doaj.org. From the journals' online author instructions we extracted information regarding endorsement of four domains of editorial policy: the Uniform Requirements for Manuscripts, trial registration, disclosure of conflicts of interest and five major reporting guidelines such as the CONSORT (Consolidated Standards of Reporting Trials statement. Two investigators collected data independently. Results The Uniform Requirements were mentioned by 27 (66% pediatric OA journals. Thirteen (32% required or recommended trial registration prior to publication of a trial report. Conflict of interest policies were stated by 25 journals (61%. Advice about reporting guidelines was less frequent: CONSORT was referred to by 12 journals (29% followed by other reporting guidelines (MOOSE, PRISMA or STARD (8 journals, 20

  6. [Good agricultural practice (GAP) of Chinese materia medica (CMM) for ten years: achievements, problems and proposals].

    Science.gov (United States)

    Guo, Lan-Ping; Zhang, Yan; Zhu, Shou-Dong; Wang, Gui-Hua; Wang, Xiu; Zhang, Xiao-Bo; Chen, Mei-Lan; He, Ya-Li; Han, Bang-Xing; Chen, Nai-Fu; Huang, Lu-Qi

    2014-04-01

    This paper aims to summarize the achievements during the implementation process of good agricultural practice (GAP) in Chinese Materia Medica (CMM), and on basis of analyzing the existing problems of GAP, to propose further implementation of GAP in TCM growing. Since the launch of GAP in CMM growing ten years ago, it has acquired great achievements, including: (1) The promulgation of a series of measures for the administration of the GAP approval in the CMM growing; (2) The expanded planting area of CMM; (3) The increased awareness of standardized CMM growing among farmers and enterprises; (4) The establishment of GAP implementation bases for CMM growing; (5) The improvement of theory and methodology for CMM growing; (6) The development of a large group of experts and scholars in GAP approval for CMM production. The problems existing in the production include: (1) A deep understanding of GAP and its certification is still needed; (2) The distribution of the certification base is not reasonable; (3) The geo-economics effect and the backward farming practices are thought to be the bottlenecks in the standardization of CMM growing and the scale production of CMM; (4) Low comparative effectiveness limits the development of the GAP; (5) The base of breeding improved variety is blank; (6) The immature of the cultivation technique lead to the risk of production process; (7) The degradation of soil microbial and the continuous cropping obstacle restrict the sustainable development of the GAP base. To further promote the health and orderly GAP in the CMM growing, the authors propose: (1) To change the mode of production; (2) To establish a sound standard system so as to ensure quality products for fair prices; (3) To fully consider the geo-economic culture and vigorously promote the definite cultivating of traditional Chinese medicinal materials; (4) To strengthen the transformation and generalization of basic researches and achievements, in order to provide technical

  7. Status of beryllium materials for fusion application

    International Nuclear Information System (INIS)

    The possible use of beryllium as a material for fusion reactors is discussed. Based on the results of recent Russian elaborations, which were not covered previously in the scientific literature, an attempt of complex analysis of the techniques of using beryllium is made. The specific requirements on beryllium as a protective material for first wall and divertor are considered. Also the possibility of creating a fusion grade of beryllium is discussed and an optimum strategy is suggested. (orig.)

  8. Developing experimental protocols for chronic irradiation studies: the application of a good practice guide framework

    International Nuclear Information System (INIS)

    The EC-funded FASSET (Framework for Assessment of Environmental Impact) project collated information on the transfer, dosimetry, and effects of ionising radiation on wildlife. A major output from the project is the FASSET Radiation Effects Database (FRED). A review of the information contained within FRED highlighted that information on the effects of low-dose, chronic exposure was, at best, fragmentary. However, these data are required to define the dose effect relationships needed to underpin the assessment tools that are being developed. To address this requirement, a series of four Good Practice Guides (GPGs) has been produced as part of a protocol development framework. This framework aims to harmonise experimental approaches, with a view to ensuring that all necessary data on appropriate endpoints are collected, so that dose effect relationships can be determined. The GPGs cover test species selection, endpoint selection, radiation exposure and experimental design considerations. A key is used to guide researchers through the GPGs and the decisions made are recorded on an output pro-forma. The completed pro-forma forms the basis of the experimental protocol. The pro-forma also indicates the information that should be included when presenting the results of the experiment. Standardising approaches ensures that results are comparable between experiments and that they are suitable for determining dose effect relationships. This protocol development framework has been adopted by the UK Environment Agency as a document upon which future Agency-funded experimental work on the effects of chronic, low-level exposure to ionising radiation will be based. It is hoped that the framework will gain acceptance in the wider scientific community and facilitate addressing the knowledge gaps that have been identified in order that successful protection of non-human biota can be demonstrated. (author)

  9. Current Good Manufacturing Practice Production of an Oncolytic Recombinant Vesicular Stomatitis Viral Vector for Cancer Treatment

    Science.gov (United States)

    Meseck, M.; Derecho, I.; Lopez, P.; Knoblauch, C.; McMahon, R.; Anderson, J.; Dunphy, N.; Quezada, V.; Khan, R.; Huang, P.; Dang, W.; Luo, M.; Hsu, D.; Woo, S.L.C.; Couture, L.

    2011-01-01

    Abstract Vesicular stomatitis virus (VSV) is an oncolytic virus currently being investigated as a promising tool to treat cancer because of its ability to selectively replicate in cancer cells. To enhance the oncolytic property of the nonpathologic laboratory strain of VSV, we generated a recombinant vector [rVSV(MΔ51)-M3] expressing murine gammaherpesvirus M3, a secreted viral chemokine-binding protein that binds to a broad range of mammalian chemokines with high affinity. As previously reported, when rVSV(MΔ51)-M3 was used in an orthotopic model of hepatocellular carcinoma (HCC) in rats, it suppressed inflammatory cell migration to the virus-infected tumor site, which allowed for enhanced intratumoral virus replication leading to increased tumor necrosis and substantially prolonged survival. These encouraging results led to the development of this vector for clinical translation in patients with HCC. However, a scalable current Good Manufacturing Practice (cGMP)-compliant manufacturing process has not been described for this vector. To produce the quantities of high-titer virus required for clinical trials, a process that is amenable to GMP manufacturing and scale-up was developed. We describe here a large-scale (50-liter) vector production process capable of achieving crude titers on the order of 109 plaque-forming units (PFU)/ml under cGMP. This process was used to generate a master virus seed stock and a clinical lot of the clinical trial agent under cGMP with an infectious viral titer of approximately 2 × 1010 PFU/ml (total yield, 1 × 1013 PFU). The lot has passed all U.S. Food and Drug Administration-mandated release testing and will be used in a phase 1 clinical translational trial in patients with advanced HCC. PMID:21083425

  10. Good Manufacturing Practices production and analysis of a DNA vaccine against dental caries

    Institute of Scientific and Technical Information of China (English)

    Ya-ping YANG; Yu-hong LI; Ai-hua ZHANG; Lan BI; Ming-wen FAN

    2009-01-01

    Aim: To prepare a clinical-grade anti-caries DNA vaccine pGJA-P/VAX and explore its immune effect and protective efficacy against a cariogenic bacterial challenge.Methods: A large-scale industrial production process was developed under Good Manufacturing Practices (GMP) by combining and optimizing common unit operations such as alkaline lysis, precipitation, endotoxin removal and column chromatography. Quality controls of the purified bulk and final lyophilized vaccine were conducted according to authoritative guidelines. Mice and gnotobiotic rats were intranasally immunized with clinical-grade pGJA-P/VAX with chitosan. Antibody levels of serum IgG and salivary SlgA were assessed by an enzyme-linked immunosorbent assay (ELISA), and caries activity was evaluated by the Keyes method. pGJA-P/VAX and pVAX1 prepared by a laboratory-scale commercial kit were used as controls.Results: The production process proved to be scalable and reproducible. Impurities including host protein, residual RNA, genomic DNA and endotoxin in the purified plasmid were all under the limits of set specifications. Intranasal vaccination with clinical-grade pGJA-P/ VAX induced higher serum IgG and salivary SlgA in both mice and gnotobiotic rats. While in the experimental caries model, the enamel (E), dentinal slight (Ds), and dentinal moderate (Dm) caries lesions were reduced by 21.1%, 33.0%, and 40.9%, respectively. Conclusion: The production process under GMP was efficient in preparing clinical-grade pGJA-P/VAX with high purity and intended effectiveness, thus facilitating future clinical trials for the anti-caries DNA vaccine.

  11. Good Cascade Impactor Practice (GCIP) and considerations for "in-use" specifications.

    Science.gov (United States)

    Nichols, S C; Mitchell, J P; Shelton, C M; Roberts, D L

    2013-03-01

    The multi-stage cascade impactor (CI) is widely used to determine aerodynamic particle size distributions (APSDs) of orally inhaled products. Its size-fractionating capability depends primarily on the size of nozzles of each stage. Good Cascade Impactor Practice (GCIP) requires that these critical dimensions are linked to the accuracy of the APSD measurement based on the aerodynamic diameter size scale. Effective diameter (Deff) is the critical dimension describing any nozzle array, as it is directly related to stage cut-point size (d50). d50 can in turn be determined by calibration using particles of known aerodynamic diameter, providing traceability to the international length standard. Movements in Deff within manufacturer tolerances for compendial CIs result in the worst case in shifts in d50 of <±10%. Stage mensuration therefore provides satisfactory control of measurement accuracy. The accurate relationship of Deff to d50 requires the CI system to be leak-free, which can be checked by sealing the apparatus at the entry to the induction port and isolating it from the vacuum source and measuring the rate of pressure rise before each use. Mensuration takes place on an infrequent basis compared with the typical interval between individual APSD determinations. Measurement of stage flow resistance (pressure drop; ΔPstage) could enable the user to know that the CI stages are fit for use before every APSD measurement, by yielding an accurate measure of Deff. However, more data are needed to assess the effects of wear and blockage before this approach can be advocated as part of GCIP. PMID:23344853

  12. Current good manufacturing practice production of an oncolytic recombinant vesicular stomatitis viral vector for cancer treatment.

    Science.gov (United States)

    Ausubel, L J; Meseck, M; Derecho, I; Lopez, P; Knoblauch, C; McMahon, R; Anderson, J; Dunphy, N; Quezada, V; Khan, R; Huang, P; Dang, W; Luo, M; Hsu, D; Woo, S L C; Couture, L

    2011-04-01

    Vesicular stomatitis virus (VSV) is an oncolytic virus currently being investigated as a promising tool to treat cancer because of its ability to selectively replicate in cancer cells. To enhance the oncolytic property of the nonpathologic laboratory strain of VSV, we generated a recombinant vector [rVSV(MΔ51)-M3] expressing murine gammaherpesvirus M3, a secreted viral chemokine-binding protein that binds to a broad range of mammalian chemokines with high affinity. As previously reported, when rVSV(MΔ51)-M3 was used in an orthotopic model of hepatocellular carcinoma (HCC) in rats, it suppressed inflammatory cell migration to the virus-infected tumor site, which allowed for enhanced intratumoral virus replication leading to increased tumor necrosis and substantially prolonged survival. These encouraging results led to the development of this vector for clinical translation in patients with HCC. However, a scalable current Good Manufacturing Practice (cGMP)-compliant manufacturing process has not been described for this vector. To produce the quantities of high-titer virus required for clinical trials, a process that is amenable to GMP manufacturing and scale-up was developed. We describe here a large-scale (50-liter) vector production process capable of achieving crude titers on the order of 10(9) plaque-forming units (PFU)/ml under cGMP. This process was used to generate a master virus seed stock and a clinical lot of the clinical trial agent under cGMP with an infectious viral titer of approximately 2 × 10(10) PFU/ml (total yield, 1 × 10(13) PFU). The lot has passed all U.S. Food and Drug Administration-mandated release testing and will be used in a phase 1 clinical translational trial in patients with advanced HCC.

  13. EXPLORING GOOD PRACTICE KNOWLEDGE TRANSFER RELATED TO POST TSUNAMI HOUSING (RE-CONSTRUCTION IN SRI LANKA

    Directory of Open Access Journals (Sweden)

    Bingunath Ingirige

    2008-12-01

    Full Text Available Sri Lanka was badly affected by the tsunami that occurred on 26th December 2004. The tsunami destroyed about two-thirds of the Sri Lankan coastline and affected more than 1,000,000 people. It does not only affected the lives of the community, but also had a devastating effect on their housing and livelihoods. The overall loss of 100,000 or more houses due to the tsunami proved to be a major challenge to the emergency response teams and disaster planners. Although several major disasters of varying magnitudes have occurred in the world, the body of knowledge related to post-disaster housing reconstruction and rehabilitation appears fragmented and poorly integrated. This paper attempts to fill this theoretical gap by focusing on the extent to which good practice knowledge transfer helps in overcoming this problem for more effective and efficient delivery of post-tsunami housing in Sri Lanka. The paper applied knowledge transfer principles within the context of the two housing reconstruction strategies employed in post-tsunami housing reconstruction in Sri Lanka; namely donor-driven housing and owner driven housing. The results of this study reveal that the knowledge transfer within this context cannot be simply copied and inserted from one context without any localisation. Therefore, the paper proposes a high-level abstraction of the core principles of community engagement through participatory techniques associated with appropriate capacity and capability building techniques that will enable the various stakeholders to create a new application to suit the appropriate context of the transfer destination (post-tsunami context in Sri Lanka.

  14. [Good practices and techniques for prevention of accidents at work and occupational diseases. New database of Inail].

    Science.gov (United States)

    Bindi, L; Ossicini, A

    2007-01-01

    The project "The publication of good practices and good techniques for prevention" is one the priorities of nail. This computerized system for the collection of good practices and standards of Good Technology is aimed to health and safety of workers. The basic objective of the database is to provide a valuable tool, usable, dynamic and implemented, in order to facilitate and direct the access to BP and BT it by people responsible for SSL. At the same time constitutes a tool strategically important for enterprises (especially SMEs) in terms of technological innovation and competitiveness, related to the prevention, safety and health of workers. The realization of this project has involved many of the professionals (chemists, engineers, doctors, biologists, geologists, etc.), and everyone gives his intake of qualified professional competence.

  15. Neutron irradiation of beryllium pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Gelles, D.S.; Ermi, R.M. [Pacific Northwest National Lab., Richland, WA (United States); Tsai, H. [Argonne National Lab., IL (United States)

    1998-03-01

    Seven subcapsules from the FFTF/MOTA 2B irradiation experiment containing 97 or 100% dense sintered beryllium cylindrical specimens in depleted lithium have been opened and the specimens retrieved for postirradiation examination. Irradiation conditions included 370 C to 1.6 {times} 10{sup 22} n/cm{sup 2}, 425 C to 4.8 {times} 10{sup 22} n/cm{sup 2}, and 550 C to 5.0 {times} 10{sup 22} n/cm{sup 2}. TEM specimens contained in these capsules were also retrieved, but many were broken. Density measurements of the cylindrical specimens showed as much as 1.59% swelling following irradiation at 500 C in 100% dense beryllium. Beryllium at 97% density generally gave slightly lower swelling values.

  16. In Search of Missing Links in Disseminating Good Practice – Experiences of a Work Reform Programme in Finland

    OpenAIRE

    Arnkil, Robert

    2008-01-01

    "This article examines learning and good practice dissemination in the light of the evolution and experience of the Finnish Workplace Development Programme (TYKES), which has been running from 1996 in Finland, and will complete its third term in 2009. The emphasis will be on the new project concept used in the second term of the Programme, namely learning networks. The concept of “good practice” is critically examined, and some ideas, pointing out to a need to pay due attent...

  17. Guidebook on good practice in the management of uranium mining and mill operations and the preparation for their closure

    International Nuclear Information System (INIS)

    Over the past fifty years the uranium industry has moved from a labor-intensive industry to a 'high-tech' and capital intensive industry. Organization of knowledge, manpower and material had to change to meet the demands of several stakeholders inherent to any project and to constantly adapt to technological innovations. Today, the mission of a uranium operation is not only to make a profit while selling yellow cake to electrical power stations but also to address issues regarding safety, health, environment and demands of the regulators and the public and assure the sustainability of the operations. Good mining practice begins with the proper planning and forecasting from the discovery of a deposit to decommissioning of a mine. This report describes and defines what is considered as good practice in the various activities of a mining operation and provides an overview of the management of a single operation. As technologies are progressing rapidly in the mining industry, and as this industry is transitional, this report emphasizes the importance of training employees at all levels of the organization. The statement on good practices for the various activities of a mining operation will be useful for organizations which are planning to open new mines or intend to modernize ongoing operations. Practical examples are given in the case of histories for four different countries. The objective of this publication is not to provide strict rules on the application of good practice but to give general guidelines that can be consulted and used in many different countries

  18. [Good medical practice for drugs. Definition, guidelines, references, field of action and applications].

    Science.gov (United States)

    2008-01-01

    Proper use of drugs can be defined as the use of the right product, in a correct dosage, during an adequate length of time, for a given patient and provided he has no serious side effects.It is virtually impossible, with such a number of drugs, such a number of clinical situations to prescribe adequately without using references or guidelines. References may lead to a unique choice, when the diagnosis is certain and the drug to be given is unique. With a good initial and continuous medical education, doctors can take easily this type of decision. The Summary of Products Characteristics (SPC) helps them; by sticking to this fundamental reference, prescription might be more precise and safe. In a lot of clinical situations the choice between a large numbers of therapeutic strategies necessitates use of a guideline based on scientific knowledge. Finally, a given therapeutic strategy can be as effective as and considerably less expensive than another. In such cases, payers can drive doctors to the prescription of the less expensive strategy.Some difficulties are common to all references and guidelines: 1. A lot of clinical situations are not covered by guidelines. 2. Guidelines should be updated each time there is a modification of knowledge: it is extremely difficult to do. 3. A great number of guidelines exist, issued by scientific community, health authorities or the payers. Sometime you can find a proposition in a guideline and the reverse in another guideline. It could be confusing. 4. Guidelines should be evaluated rigorously to know if they fulfil their goals. 5. Some of those guidelines simply cannot help doctors. They are too complex or do not take into account practical situations.We have made an inventory of those various guidelines and their weaknesses and we propose some solutions to increase their utility. We propose an analysis of the situation and some solutions to improve the quality and the relevance of the guidelines: to create groups of coordination

  19. Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks

    Directory of Open Access Journals (Sweden)

    Polchow Bianca

    2012-05-01

    Full Text Available Abstract Background In vitro fabricated tissue engineered vascular constructs could provide an alternative to conventional substitutes. A crucial factor for tissue engineering of vascular constructs is an appropriate cell source. Vascular cells from the human umbilical cord can be directly isolated and cryopreserved until needed. Currently no cell bank for human vascular cells is available. Therefore, the establishment of a future human vascular cell bank conforming to good manufacturing practice (GMP conditions is desirable for therapeutic applications such as tissue engineered cardiovascular constructs. Materials and methods A fundamental step was the adaption of conventional research and development starting materials to GMP compliant starting materials. Human umbilical cord artery derived cells (HUCAC and human umbilical vein endothelial cells (HUVEC were isolated, cultivated, cryopreserved (short- and long-term directly after primary culture and recultivated subsequently. Cell viability, expression of cellular markers and proliferation potential of fresh and cryopreserved cells were studied using trypan blue staining, flow cytometry analysis, immunofluorescence staining and proliferation assays. Statistical analyses were performed using Student’s t-test. Results Sufficient numbers of isolated cells with acceptable viabilities and homogenous expression of cellular markers confirmed that the isolation procedure was successful using GMP compliant starting materials. The influence of cryopreservation was marginal, because cryopreserved cells mostly maintain phenotypic and functional characteristics similar to those of fresh cells. Phenotypic studies revealed that fresh cultivated and cryopreserved HUCAC were positive for alpha smooth muscle actin, CD90, CD105, CD73, CD29, CD44, CD166 and negative for smoothelin. HUVEC expressed CD31, CD146, CD105 and CD144 but not alpha smooth muscle actin. Functional analysis demonstrated acceptable

  20. PATONGO: Patterns and Tools for Non-Profit Organizations—a pattern-based approach for helping volunteers to identify and share good practice

    Science.gov (United States)

    Schümmer, Till; Haake, Jörg M.

    2010-04-01

    Identification and sharing of good practice is an essential ingredient for collaborative voluntary action in non-profit organizations. While current approaches for sharing good practice focus on adopting and describing good practice individually, they fail to address collaborative detection, description, and appropriation of good practice in organizations. We propose a pattern-based approach, which facilitates collaborative creation, improvement, and sharing of good practice via Web 2.0 concepts. First experiences with the approach are presented including a field experiment where the approach was implemented in the Evangelic Church of Germany.

  1. Study of beryllium redeposition under bombardment by high intensity -low energy- hydrogen ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Gureev, V.M.; Guseva, M.I.; Danelyan, L.S. [Russian Research Centre Kurchatov Inst., Moscow (Russian Federation)] [and others

    1998-01-01

    The results of studying the erosion of beryllium under an effect of intense ion fluxes with the energy of 250 eV, at the fluences {approx}10{sup 2}1 cm{sup -2}, at the MAGRAS-stand are given. The operating conditions under which a practically-complete redeposition of the sputtered beryllium upon the target surface were experimentally-realized. A change in the microstructure of a beryllium target under sputtering and redeposition is analyzed. Some technological applications are considered. (author)

  2. Reactivity test between beryllium and copper

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, H. [Japan Atomic Energy Research Institute, Ibaraki-ken (Japan); Kato, M. [NGK Insulators, Ltd., Aichi-ken (Japan)

    1995-09-01

    Beryllium has been expected for using as plasma facing material on ITER. And, copper alloy has been proposed as heat sink material behind plasma facing components. Therefore, both materials must be joined. However, the elementary process of reaction between beryllium and copper alloy does not clear in detail. For example, other authors reported that beryllium reacted with copper at high temperature, but it was not obvious about the generation of reaction products and increasing of the reaction layer. In the present work, from this point, for clarifying the elementary process of reaction between beryllium and copper, the out-of-pile compatibility tests were conducted with diffusion couples of beryllium and copper which were inserted in the capsule filled with high purity helium gas (6N). Annealing temperatures were 300, 400, 500, 600 and 700{degrees}C, and annealing periods were 100, 300 and 1000h. Beryllium specimens were hot pressed beryllium, and copper specimens were OFC (Oxygen Free Copper).

  3. Profile of establishments in the supermarket sector with respect to good practices in the city of Santa Maria (RS, Brazil

    Directory of Open Access Journals (Sweden)

    Carla Cristina Bauermann Brasil

    2013-12-01

    Full Text Available The objective of this study was to verify the compliance of the supermarket sector with respect to the Good Practice Program standards of the city of Santa Maria (RS, Brazil. Sixty nine establishments were verified using a checklist of good practices for the supermarket sector in Santa Maria, RS (Brazil, from April to July 2011. The data were collected by a food safety and quality professional using this checklist. The results showed that the overall adequacy of the establishments surveyed was 29.07%. The highest percentage of compliance was found for storage at ambient temperature (64.13%. The lowest compliance percentage was also found in different sections and areas in the supermarkets such as bakery and confectionery (14.93%, water supply (18.30%, food handling (21.01%, sausage and cold meat (or deli meat (36.38%, and documentation-related items (4.97%. None of the supermarkets evaluated had the necessary documentation for the implementation of good practices. The results of this study show the importance of effectively implementing a good practice program and quality systems by raising awareness among technicians and professionals of the importance of quality programs used in food companies and the need for more thorough inspection delivered by competent authorities to ensure food safety for consumers.

  4. Good practices in decommissioning planning and pre-decommissioning activities for the Magurele VVR-S nuclear research reactor

    OpenAIRE

    Dragusin Mitica; Pavelescu Octavian Alexandru; Iorga Ioan

    2011-01-01

    The VVR-S Nuclear Research Reactor at the “Horia Hulubei” National Institute of Physics and Nuclear Engineering in Magurele, Bucharest, will be decommissioned applying the immediate dismantling strategy. The implementation of the decommissioning project started in 2010 and is planned for completion within 11 years. Good practices in decommissioning planning, organization, funding, and logistics are described in this paper.

  5. Ideas and Realities: Investigating Good Practice in the Management of Transnational English Language Programmes for the Higher Education Sector

    Science.gov (United States)

    Dunworth, Katie

    2008-01-01

    This paper describes the findings of an Australian Government-funded research project that sought to investigate the management of transnational English-language teaching programmes in the higher education sector with a view to identifying those activities that both facilitate and inhibit good practice as defined in the paper. Using data obtained…

  6. Analysis of constraints for compliance to Good Agricultural Practices by the horticultural sector in Indonesia : project report 2011

    NARCIS (Netherlands)

    Koomen, I.; Zulkarnain, I.; Suleaman, A.; Ruting, A.

    2012-01-01

    The horticultural industry in Indonesia is progressively moving to apply Good Agricultural Practices (GAP) with the aim of producing sustainably as well as guaranteeing food safety. While the Ministry of Agriculture has put a lot of effort in assisting farmers to comply to the national IndoGAP and b

  7. Good practice in health care for migrants: views and experiences of care professionals in 16 European countries

    Directory of Open Access Journals (Sweden)

    Stankunas Mindaugas

    2011-03-01

    Full Text Available Abstract Background Health services across Europe provide health care for migrant patients every day. However, little systematic research has explored the views and experiences of health care professionals in different European countries. The aim of this study was to assess the difficulties professionals experience in their service when providing such care and what they consider constitutes good practice to overcome these problems or limit their negative impact on the quality of care. Methods Structured interviews with open questions and case vignettes were conducted with health care professionals working in areas with high proportion of migrant populations in 16 countries. In each country, professionals in nine primary care practices, three accident and emergency hospital departments, and three community mental health services (total sample = 240 were interviewed about their views and experiences in providing care for migrant patients, i.e. from first generation immigrant populations. Answers were analysed using thematic content analysis. Results Eight types of problems and seven components of good practice were identified representing all statements in the interviews. The eight problems were: language barriers, difficulties in arranging care for migrants without health care coverage, social deprivation and traumatic experiences, lack of familiarity with the health care system, cultural differences, different understandings of illness and treatment, negative attitudes among staff and patients, and lack of access to medical history. The components of good practice to overcome these problems or limit their impact were: organisational flexibility with sufficient time and resources, good interpreting services, working with families and social services, cultural awareness of staff, educational programmes and information material for migrants, positive and stable relationships with staff, and clear guidelines on the care entitlements of different

  8. Worker Environment Beryllium Characterization Study

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environment, Safety, Health & Quality

    2009-12-28

    This report summarizes the conclusion of regular monitoring of occupied buildings at the Nevada Test Site and North Las Vegas facility to determine the extent of beryllium (Be) contamination in accordance with Judgment of Needs 6 of the August 14, 2003, “Minnema Report.”

  9. Worker Environment Beryllium Characterization Study

    International Nuclear Information System (INIS)

    This report summarizes the conclusion of regular monitoring of occupied buildings at the Nevada Test Site and North Las Vegas facility to determine the extent of beryllium (Be) contamination in accordance with Judgment of Needs 6 of the August 14, 2003, 'Minnema Report.'

  10. What Is a Good Tomato? A Case of Valuing in Practice

    Directory of Open Access Journals (Sweden)

    Frank Heuts

    2013-11-01

    Full Text Available As a contribution to the field of valuation studies this article lays out a number of lessons that follow from an exploratory inquiry into 'good tomatoes'. We held interviews with tomato experts (developers, growers, sellers, processors, professional cooks and so-called consumers in the Netherlands and analysed the transcriptions carefully. Grouping our informants' concerns with tomatoes into clusters, we differentiate between five registers of valuing. These have to do with money, handling, historical time, what it is to be natural, and sensual appeal. There are tensions between and within these registers that lead to clashes and compromises. Accordingly, valuing tomatoes does not fit into inclusive formal schemes. Neither is it simply a matter of making judgements. Our informants told us how they know whether a tomato is good, but also revealed what they do to make tomatoes good. Their valuing includes activities such as pruning tomato plants and preparing tomato dishes. But if such activities are meant to make tomatoes good, success is never guaranteed. This prompts us to import the notion of care. Care does not offer control, but involves sustained and respectful tinkering towards improvement. Which is not to say in the end the tomatoes our informants care for are good. In the end these tomatoes get eaten. And while eating performs tomatoes as 'good to eat', it also finishes them off. Valuing may lead on to destruction. An important lesson for valuation studies indeed.

  11. Report of the consultants meeting on good manufacturing practices and clean room requirements for radiopharmaceuticals

    International Nuclear Information System (INIS)

    carried out in special facilities often with shielding and remote handling to protect the operators from radiation exposure. There are international norms for radiation exposure allowed for radiation workers and strong national organizations for monitoring and implementing radiation protection measures. Being part of the national nuclear programmes, radiopharmaceutical production has been from the very beginning subjected to regulations of radioactive material handling, transportation and use. However, the systems of surveillance and control for pharmaceutical products have not been implemented in many places to the same extent as for radiation protection. There are also technical difficulties in harmonizing the requirements of radiation safety and pharmaceutical safety. Simultaneously, there have been several technical developments in the field of Quality Assurance of pharmaceuticals. The concepts of Good Manufacturing Practices (GMP) and the requirements for clean rooms define quality of air for pharmaceutical production areas. Efforts have been made in recent years to apply these concepts also to radiopharmaceutical production. Significant progress appears to have been made in the developed countries and in the technology needed to fulfil these standards. The technical problems in upgrading the facilities of radioisotope laboratories to conform with the clean air requirements and the cost involved are still to be clearly understood in many developing countries. In many countries the regulatory authorities apply the same set of regulations for radiopharmaceuticals as for other pharmaceuticals. Some guidelines for radiopharmaceuticals have been published, e.g. Scandinavian, US FDA, Australian, Canadian and EU guidelines. No such guidelines are yet available from international agencies such as the International Atomic Energy Agency (IAEA) or World Health Organization (WHO). A guideline from an international body of this nature would be very useful for institutions working

  12. [Good experiences with collaboration between research and practice in public health

    DEFF Research Database (Denmark)

    Larsen, Maja; Gulis, Gabriel; Bak, Carsten Kronborg;

    2011-01-01

    delivered, and support in project development. Challenges experienced: different working traditions, translating research into practical know-how, and lack of capacity for knowledge exchange. Future development will include building capacity for knowledge exchange and finding methods for handling...

  13. Good teachers and deviant learners: The meeting of practices in university level international education

    DEFF Research Database (Denmark)

    Jensen, Iben; Tange, Hanne

    2012-01-01

    The article focuses on the impact of internationalization on university lecturers’ practice. Based on interviews with 36 employees from Danish universities, we discuss what internationalization means for the classroom relationship between university teachers and international students. The article......, classroom practices and student/staff roles, we propose that an intercultural pedagogy be developed, underlining the need for a symmetrical learning and teaching platform in international education....

  14. Towards good pharmacy practice in Hanoi : A multi-intervention study in private sector

    OpenAIRE

    Chuc, Nguyen Thi Kim

    2002-01-01

    This thesis describes the quality of private pharmacy practice and assesses the effects of an intervention package on knowledge and practice of private pharmacy staff in Hanoi, Vietnam. The study types used were a case study and a randomised controlled trial. In the case study, two private pharmacies were included. Interviews, observations and drug inventory were used for data collection. In the intervention study, 68 private pharmacies participated. A Simulated Client M...

  15. Practical discrimination of good and bad cooked food using metal oxide semiconductor odour sensor

    Directory of Open Access Journals (Sweden)

    Essiet Ima O.

    2013-01-01

    Full Text Available An increasing concentration of ammonia in cooked food is in direct proportion to the extent of decay. This fact is used to design an electronic nose (e-nose based on metal oxide semiconductor odour sensor circuit capable of discriminating good and bad cooked food. On the basis of the data produced by the e-nose circuit, a feedforward multilayer neural network is designed and trained to recognize varying concentrations of ammonia in the food. Test results of the prototype e-nose system show that it is capable of classifying cooked food as being good or bad with over 92% average success rate.

  16. OVERVIEW OF BERYLLIUM SAMPLING AND ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    Brisson, M

    2009-04-01

    Because of its unique properties as a lightweight metal with high tensile strength, beryllium is widely used in applications including cell phones, golf clubs, aerospace, and nuclear weapons. Beryllium is also encountered in industries such as aluminium manufacturing, and in environmental remediation projects. Workplace exposure to beryllium particulates is a growing concern, as exposure to minute quantities of anthropogenic forms of beryllium may lead to sensitization and to chronic beryllium disease, which can be fatal and for which no cure is currently known. Furthermore, there is no known exposure-response relationship with which to establish a 'safe' maximum level of beryllium exposure. As a result, the current trend is toward ever lower occupational exposure limits, which in turn make exposure assessment, both in terms of sampling and analysis, more challenging. The problems are exacerbated by difficulties in sample preparation for refractory forms of beryllium, such as beryllium oxide, and by indications that some beryllium forms may be more toxic than others. This chapter provides an overview of sources and uses of beryllium, health risks, and occupational exposure limits. It also provides a general overview of sampling, analysis, and data evaluation issues that will be explored in greater depth in the remaining chapters. The goal of this book is to provide a comprehensive resource to aid personnel in a wide variety of disciplines in selecting sampling and analysis methods that will facilitate informed decision-making in workplace and environmental settings.

  17. Beryllium - A Unique Material in Nuclear Applications

    International Nuclear Information System (INIS)

    Beryllium, due to its unique combination of structural, chemical, atomic number, and neutron absorption cross section characteristics, has been used successfully as a neutron reflector for three generations of nuclear test reactors at the Idaho National Engineering and Environmental Laboratory (INEEL). The Advanced Test Reactor (ATR), the largest test reactor in the world, has utilized five successive beryllium neutron reflectors and is scheduled for continued operation with a sixth beryllium reflector. A high radiation environment in a test reactor produces radiation damage and other changes in beryllium. These changes necessitate safety analysis of the beryllium, methods to predict performance, and appropriate surveillances. Other nuclear applications also utilize beryllium. Beryllium, given its unique atomic, physical, and chemical characteristics, is widely used as a ''window'' for x-rays and gamma rays. Beryllium, intimately mixed with high-energy alpha radiation emitters has been successfully used to produce neutron sources. This paper addresses operational experience and methodologies associated with the use of beryllium in nuclear test reactors and in ''windows'' for x-rays and gamma rays. Other nuclear applications utilizing beryllium are also discussed

  18. Raising the Achievement of Portuguese Pupils in British Schools: A Case Study of Good Practice

    Science.gov (United States)

    Demie, Feyisa; Lewis, Kirstin

    2010-01-01

    The aim of the research was to study the experiences of Portuguese heritage pupils in British schools. The main findings from empirical data suggest Portuguese children are underachieving at the end of primary education but the case study confirms that in good schools Portuguese pupils do well and have made huge improvements over the periods. The…

  19. The advanced practice professionals' perspective: keys to a good working relationship between advanced practice professions and physicians.

    Science.gov (United States)

    Polansky, Maura

    2013-01-01

    A strong working relationship between advanced practice professionals (APPs) and supervising oncologists is essential for reducing medical errors, retaining employees, and improving work environments. Although there is rather limited data on the unique relationship of the APP and physician, fundamental communication skills-including open communication, mutual respect, establishing expectations, and working with mutual purpose-should be the foundation of these relationships. This paper addresses various aspects of relationship building between APPs and physicians with suggestions for establishing successful working relationships.

  20. Investigation of External Audit’s Good Practices in the Context of Corporate Governance - Evidence from Romania

    Directory of Open Access Journals (Sweden)

    Cristina Boţa-Avram

    2012-02-01

    Full Text Available The main objective of this study is to develop an investigation based on an empirical survey over the auditors’ perceptions about the external audit good practices that should be applied or at least recommended in the context of corporate governance. This present study also aims to detect the current applicability of the proposed external audit practices tested through this survey. In order to achieve the proposed objectives, a statistical analysis was conducted based on data obtained from questionnaires submitted to a significant sample of Romanian auditors, all respondents having the quality of members of Chambers of Financial Auditors of Romania, which is the main professional body that has responsibilities in coordinating the audit activity in Romanian context. In spite of the lower response rate, the value of the paper is argued by the fact that the findings are relevant for both academics and practitioners, because it could represent a relevant starting point in developing an integrated framework of good audit practices, including external audit practices and offering, in the same time, potential suggestions for enhancing external audit practices in the corporate governance’s area, anarea which has grown very fast in the last years, since the collapse of Enron in 2001 and the financial scandals of other companies from different countries, which strongly affect the investor confidence in the reliability of its investments.

  1. Web-based Learning Environments Guided by Principles of Good Teaching Practice.

    Science.gov (United States)

    Chizmar, John F.; Walbert, Mark S.

    1999-01-01

    Describes the preparation and execution of a statistics course, an undergraduate econometrics course, and a microeconomic theory course that all utilize Internet technology. Reviews seven principles of teaching practice in order to demonstrate how to enhance the quality of student learning using Web technologies. Includes reactions by Steve Hurd…

  2. Guideline to good practices for facility condition inspections at DOE nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This guide is intended to provide a means for owner/operators to have an awareness of the way business is actually being conducted on the shop floor. Also, this guide is intended to provide a means for maintenance managers to impart their expectations to crafts persons as to how maintenance should be conducted. It is expected that each DOE facility may use different approaches or methods than those defined in this guide. Explanation of the intent of this guide is provided in the Discussion section, and the specific guidelines that follow reflect generally accepted industry practices. In some cases, example situations accompany these guidelines. These examples have been provided only as an aid in clear understanding of the guidelines and should not be construed as the only method for meeting the intent of the guidelines. Therefore, deviation from any particular guideline would not, in itself, indicate a problem. If substantive differences exist between the intent of the Guideline and actual practice, management should evaluate current practice to determine the need to include/exclude proposed features. A change to maintenance practice would be appropriate if a performance weakness was determined to exist. Development, documentation, and implementation of other features which further enhance these guidelines for specific applications, is encouraged.

  3. Identification of good practices for teachers and students training activity in the ENVRIPLUS project

    Science.gov (United States)

    D'Addezio, Giuliana; Marsili, Antonella; Beranzoli, Laura

    2016-04-01

    We elaborated basic guiding principles that will be used to improve the content of the ENVRIPLUS e-Training Platform for multimedia education of Secondary School level teachers and students. The purpose is to favour teacher training and consequently students training on selected scientific themes faced within the ENVRIPLUS Research Infrastructures. "Best practices" could positively impacts on students by providing motivation on promoting scientific research and to increase the awareness of the Earth System complexity and Environmental challenges for its preservation and sustainability. Best practice teaching strategies represent an inherent part of a curriculum that exemplifies the connection and relevance identified in education research. The actions are designed to develop thinking and problem-solving skill through integration and active learning. Relationships are built though opportunities for communication and teamwork. Best practices motivate, engage and prompt student to learn and achieve. A starting list of principles is discussed in respect of the following main Best Practices pillars: • Identify the conceptual framework of the subject of the dissemination • Increase personal awareness of the individual potential • Easy personal elaboration and the connection of the subject with the school curriculum.

  4. Good CoP: What Makes a Community of Practice Successful?

    Science.gov (United States)

    Baker, Anthony; Beames, Stephanie

    2016-01-01

    We have established a community of practice focussed on student learning in first-year science. It is recognised that transition, whether from school to university or other possible transitions, is an issue that is a concern for the entire sector, and this is acknowledged both at Faculty and University level. One of the factors to which we…

  5. "Really Good Ideas?" Developing Evidence-Informed Policy and Practice in Education Leadership and Management.

    Science.gov (United States)

    Levacic, Rosalind; Glatter, Ron

    2001-01-01

    Examines the potential for evidence-informed policy and practice (EIPP) in relation to educational leadership. Considers definitions, models, and factors promoting and inhibiting development of EIPP as a professional norm. Discusses two collaborative efforts to organize the validation stage of the EIPP cycle. (Contains 60 references.) (MLH)

  6. Being good neighbours : Current practices, barriers, and opportunities for community engagement in Australian plantation forestry

    NARCIS (Netherlands)

    Gordon, Melissa; Schirmer, Jacki; Lockwood, Michael; Vanclay, Frank; Hanson, Dallas

    2013-01-01

    Although community engagement (CE) is widely recognised as an essential element of sustainable management, few studies have evaluated CE at an industry-wide scale, i.e. in terms of the specific CE needs and best practice methods needed when addressing engagement issues that apply across more than on

  7. Good Teachers and Deviant Learners? The Meeting of Practices in University Level International Education

    Science.gov (United States)

    Tange, Hanne; Jensen, Iben

    2012-01-01

    The article focuses on the impact of internationalization on university lecturers' practice. Based on interviews with 36 employees from Danish universities, we discuss what internationalization means for the classroom relationship between university teachers and international students. The article is inspired by an intercultural communication…

  8. Beyond "It Was Good": Students' Post-Study Abroad Practices for Negotiating Meaning

    Science.gov (United States)

    Kortegast, Carrie A.; Boisfontaine, M. Terral

    2015-01-01

    Student participation in short-term study abroad programs has increased at a rapid pace; however, little is known about students' post--study abroad practices regarding negotiating meaning of their experiences. The purpose of this study is to explore students' post-study abroad participation and reification of their experiences using the…

  9. [Good experiences with collaboration between research and practice in public health

    DEFF Research Database (Denmark)

    Larsen, Maja; Gulis, Gabriel; Bak, Carsten Kronborg;

    2011-01-01

    delivered, and support in project development. Challenges experienced: different working traditions, translating research into practical know-how, and lack of capacity for knowledge exchange. Future development will include building capacity for knowledge exchange and finding methods for handling...... the organisational barriers....

  10. Good Teaching? An Examination of Culturally Relevant Pedagogy as an Equity Practice

    Science.gov (United States)

    Schmeichel, Mardi

    2012-01-01

    The adoption of educational policy measures to close the achievement gap, as well as the significant amount of scholarship dedicated to the subject, are just some of the indicators that reflect the tremendous concern in education about the academic performance of students of colour. Within research aimed at promoting equitable practices in…

  11. Preconcentration and separation of ultra-trace beryllium using quinalizarine-modified magnetic microparticles

    Energy Technology Data Exchange (ETDEWEB)

    Ashtari, Parviz, E-mail: pashtari@aeoi.org.ir [State Key Laboratory of Chemo/Biosensing and Chemometrics, Biomedical Engineering Center, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082 (China); NFCS, Nuclear Science and Technology Research Institute, PO Box 11365-8486, Tehran (Iran, Islamic Republic of); Wang Kemin; Yang Xiaohai [State Key Laboratory of Chemo/Biosensing and Chemometrics, Biomedical Engineering Center, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082 (China); Ahmadi, Seyed Javad [NFCS, Nuclear Science and Technology Research Institute, PO Box 11365-8486, Tehran (Iran, Islamic Republic of)

    2009-07-30

    Magnetically-assisted chemical separation/preconcentration method for the analysis of beryllium from aqueous solutions was developed. According to this method several extractants were coated on certain magnetic microparticles to assist the extraction of beryllium from the aqueous solutions. The influence of different parameters (type and amount of extractant, pH, equilibrium time and ionic strength) was investigated. Also, the interfering effect of various cationic and anionic species on the percent recovery of beryllium was studied. The applied spectrophotometric method showed good linearity and precision at a given wavelength (605.0 nm). Among the extractants used, quinalizarine resulted in almost a full recovery of beryllium at pH 7.4, which was the optimum extraction pH. The equilibrium time of the extraction was 10.0 min. The quantitative re-extraction was carried out by 0.5 M nitric acid. Also, the stability of the extractant-coated magnetic microparticles was 4 cycles (extraction and re-extraction) and the used magnetic microparticles showed good selectivity for beryllium against other cations and anions. Finally, the developed method was applicable for the preconcentration and separation of beryllium from spring water, tap water and certified reference waters. The obtained detection limit was 30 ng L{sup -1}.

  12. Standard operating procedure for the good manufacturing practice-compliant production of human bone marrow mesenchymal stem cells.

    Science.gov (United States)

    Roseti, Livia; Serra, Marta; Bassi, Alessandra

    2015-01-01

    According to the European Regulation (EC 1394/2007), Mesenchymal Stem Cells expanded in culture for clinical use are considered as Advanced Therapy Medicinal Products. As a consequence, they must be produced in compliance with Good Manufacturing Practice in order to ensure safety, reproducibility, and efficacy. Here, we report a Standard Operating Procedure describing the Good Manufacturing Practice-compliant production of Bone Marrow-derived Mesenchymal Stem Cells suitable for autologous implantation in humans. This procedure can be considered as a template for the development of investigational medicinal Mesenchymal Stem Cells-based product protocols to be enclosed in the dossier required for a clinical trial approval. Possible clinical applications concern local uses in the regeneration of bone tissue in nonunion fractures or in orthopedic and maxillofacial diseases characterized by a bone loss.

  13. Regulatory requirements in the good manufacturing practice production of an epithelial cell graft for ocular surface reconstruction.

    Science.gov (United States)

    Sheth-Shah, Radhika; Vernon, Amanda J; Seetharaman, Shankar; Neale, Michael H; Daniels, Julie T

    2016-04-01

    In the past decade, stem cell therapy has been increasingly employed for the treatment of various diseases. Subsequently, there has been a great interest in the manufacture of stem cells under good manufacturing practice, which is required by law for their use in humans. The cells for sight Stem Cell Therapy Research Unit, based at UCL Institute of Ophthalmology, delivers somatic cell-based and tissue-engineered therapies to patients suffering from blinding eye diseases at Moorfields Eye Hospital (London, UK). The following article is based on our experience in the conception, design, construction, validation and manufacturing within a good manufacturing practice manufacturing facility based in the UK. As such the regulations can be extrapolated to the 28 members stated within the EU. However, the principles may have a broad relevance outside the EU.

  14. Mutagenicity, carcinogenicity and teratogenicity of beryllium.

    Science.gov (United States)

    Léonard, A; Lauwerys, R

    1987-07-01

    The carcinogenicity of a number of beryllium compounds has been confirmed in experiments on laboratory animals and this metal has to be treated as a possible carcinogenic threat to man. These carcinogenic properties are associated with mutagenic activity as shown by the results of short-term tests performed in vitro with beryllium chloride and beryllium sulfate. These soluble beryllium compounds can produce some infidelity of in vitro synthesis, forward gene mutations in microorganisms and in mammalian cells. They are also able to induce cell transformation. In addition to the positive results obtained in several short-term assays beryllium compounds have been found to bind to nucleoproteins, to inhibit certain enzymes needed for DNA synthesis, to bind nucleic acids to cell membranes and to inhibit microtubule polymerization. The teratogenicity of beryllium salts is relatively unknown and needs additional investigation.

  15. Good practice in social care: the views of people with severe and complex needs and those who support them.

    Science.gov (United States)

    Gridley, Kate; Brooks, Jenni; Glendinning, Caroline

    2014-11-01

    This paper reports findings drawn from a study of good practice in English social care for adults with disability and older people with severe and complex needs. People with severe and complex needs are a relatively small proportion of adult social care service users, but they are growing in numbers and have resource-intensive needs. The study involved qualitative research with adults with disability and older people with severe and complex needs, family carers and members of specialist organisations (n = 67), focusing on the features of social care services they considered to be good practice. Data were collected between August 2010 and June 2011. The approach to data collection was flexible, to accommodate participants' communication needs and preferences, including face-to-face and telephone interviews, Talking Mats(©) sessions and a focus group. Data were managed using Framework and analysed thematically. Features of good practice were considered at three levels: (i) everyday support; (ii) service organisation; and (iii) commissioning. Findings relating to the first two of these are presented here. Participants emphasised the importance of person-centred ways of working at all levels. Personalisation, as currently implemented in English social care, aims to shift power from professionals to service users through the allocation of personal budgets. This approach focuses very much on the role of the individual in directing his/her own support arrangements. However, participants in this study also stressed the importance of ongoing professional support, for example, from a specialist key worker or case manager to co-ordinate diverse services and ensure good practice at an organisational level. The paper argues that, despite the recent move to shift power from professionals to service users, people with the most complex needs still value support from professionals and appropriate organisational support. Without these, they risk being excluded from the benefits

  16. Good practices in decommissioning planning and pre-decommissioning activities for the Magurele VVR-S nuclear research reactor

    Directory of Open Access Journals (Sweden)

    Dragusin Mitica

    2011-01-01

    Full Text Available The VVR-S Nuclear Research Reactor at the “Horia Hulubei” National Institute of Physics and Nuclear Engineering in Magurele, Bucharest, will be decommissioned applying the immediate dismantling strategy. The implementation of the decommissioning project started in 2010 and is planned for completion within 11 years. Good practices in decommissioning planning, organization, funding, and logistics are described in this paper.

  17. Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL)

    OpenAIRE

    Todd, Christopher A.; Sanchez, Ana M.; Garcia, Ambrosia; Thomas N Denny; Sarzotti-Kelsoe, Marcella

    2013-01-01

    The EQAPOL contract was awarded to Duke University to develop and manage global proficiency testing programs for flow cytometry-, ELISpot-, and Luminex bead-based assays (cytokine analytes), as well as create a genetically diverse panel of HIV-1 viral cultures to be made available to National Institutes of Health (NIH) researchers. As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting ...

  18. Good Practices Preceding the Implementation of the System of Management of Environment, on Small and Medium Enterprises

    OpenAIRE

    Anca Atanase; Ion Schileru; Smaranda Vişan

    2011-01-01

    The current and future economic context compel to ample reconsiderations related to the volume and content of the demarches carried out by organisations, in order to face the competition sharper and sharper and the more and more numerous rigors, among which the issue of environment is more than imperative. The good practices in environment management become more and more necessary and, fortunately, are supplied more and more often by organisations in SMEs category, which encounter highly valu...

  19. Raising awareness for energy efficiency in the service sector: learning from success stories to disseminate good practices

    OpenAIRE

    Broc, Jean-Sébastien; Combes, Bertrand; Hartmann, Sandrine; Bourges, Bernard; Fernandez, Marie-Isabelle; Adnot, Jérôme

    2006-01-01

    Energy efficiency in the service sector is a key issue because of the important growth of its energy consumption. The energy performance of buildings and equipment can be improved through technical investments, but this has to be linked with an efficient management and good practices in order to reach better energy efficiency levels in a cost-effective way. Experience feedback concerning awareness activities in the service sector highlights the interesting opportunities of energy efficiency i...

  20. Development of Good Agricultural Practices(GAP) in Thailand : A case study of Thai National GAP selected products

    OpenAIRE

    Pongvinyoo, Pongthong

    2015-01-01

    Purpose and Objectives Good Agricultural Practices or GAP is a global appropriate cultivation method for the farmers to conduct food safety. It is an appropriate on-farm into farm gate cultivation management included, farm inputs selection, farm management, until post-harvest management. GAP aims to encourage the farmers to produce the safety agricultural products for the consumers. After FAO introduced GAP for a period of time, it become one of the minimum requirements for the agricultur...

  1. Linking climate smart agriculture and good agriculture practices: case studies on consumption potatoes in South Africa, the Netherlands and Ethiopia

    OpenAIRE

    Hengsdijk, H.; Verhagen, A.

    2013-01-01

    Recently, the concept of Climate Smart Agriculture has been coined in an attempt to overcome existing barriers among food security, adaptation of agriculture to climate change, and mitigation of greenhouse gas (GHG) emissions. Because the goals of CSA ultimately need to be achieved by farmers it is important to link and integrate CSA goals with Good Agricultural Practices (GAP). Although the general scope of GAP is clear, i.e. sustainable agricultural intensification, there is little common g...

  2. Residential services for individuals with intellectual disabilities in Chile. Moving towards good practices

    Directory of Open Access Journals (Sweden)

    Vanessa del Pilar Vega Cordova

    2013-07-01

    Full Text Available This study aims to understand the vision and practices of service providers on care provided and its relation to the support and quality of life of institutionalized Chileans with intellectual disabilities. The methodology used consisted of content analysis of the information obtained from three service provider focus groups. The results indicate that while progress is being made in the quality of services offered to these users, it is necessary to take another step to move from the provision of essential services to the promotion, recording and tracking of quality results. This change requires a joint effort at the different levels of the system, including public policies that focus on personal development opportunities and personal outcome, as well as professionals committed to the promotion of best practices.

  3. Good practice recommendations - medical-professional control of internal exposure to radionuclides in nuclear base installations

    International Nuclear Information System (INIS)

    The first part of this voluminous report presents the context and method of definition of recommendations for a clinical practice and comprises a literature review of national, European and international recommendations, standards and work-group reports. The second part develops recommendations under four main themes: assessment of the committed effective dose (objectives, implementation, communication, traceability and archiving), control programs, dosimetric estimation based on results, and health risk and taking into care by the occupational physician. The authors adopted the same structure for each sub-theme or issue: target extract of regulatory and standard requirements and international recommendations, analysis of literature and of data from professional practices, opinion of the work-group, and graded recommendations with respect to the proof level

  4. Inhibited solid propellant composition containing beryllium hydride

    Science.gov (United States)

    Thompson, W. W. (Inventor)

    1978-01-01

    An object of this invention is to provide a composition of beryllium hydride and carboxy-terminated polybutadiene which is stable. Another object of this invention is to provide a method for inhibiting the reactivity of beryllium hydride toward carboxy-terminated polybutadiene. It was found that a small amount of lecithin inhibits the reaction of beryllium hydride with the acid groups in carboxy terminated polybutadiene.

  5. Critical Analysis of Good Governance Practices in entral Bank : The Case of Bank Indonesia

    OpenAIRE

    MARSUKI, MARSUKI

    2012-01-01

    Abstract Bank Indonesia (BI) is one of the ???independent??? state institution which is mandated by the Indonesian Constitution of 1945 and Law on Bank Indonesia to manage the economic resource or financial potential of the Indonesian people in order to facilitate its strategic function as the monetary authority, banking authority and authority in payment system. In practice, BI is a public institution but with certain characteristics of corporate institution, as reflecte...

  6. Internal Audit in the Pharmaceutical Sector: International and National Good Practices

    OpenAIRE

    Tsvetanova, Yulia

    2014-01-01

    Internal audit plays an increasingly important role in the field of management. In today's economic environment, means and methods to achieve high financial performance in the medium and long-term perspective are purposefully sought. In the new reality, practice puts an emphasis on the need for additional control on the activities which, in turn, justifies concrete changes in the policy of the organizations as well. In terms of the individual organization, the implementation of internal audit...

  7. State Master Gardeners Knowledge and Behavior Regarding Food Safety and Good Agricultural Practices Recommendations

    OpenAIRE

    Brennan, Christy

    2009-01-01

    Master Gardener’s (MG) are volunteers that dedicate their time and resources to complete advanced training on gardening practices. They are a valuable resource to state Cooperative Extension services, like the one in Virginia (VCE), by volunteering to share gardening knowledge with the public. MG’s assist the public in starting and maintaining personal and community fruit and vegetable gardens. Food producing gardens should be treated differently from recreational gardens. Gardening and harve...

  8. Recommended design correlations for S-65 beryllium

    International Nuclear Information System (INIS)

    The properties of tritium and helium behavior in irradiated beryllium are reviewed, along with the thermal-mechanical properties needed for ITER design analysis. Correlations are developed to describe the performance of beryllium in a fusion reactor environment. While this paper focuses on the use of beryllium as a plasma-facing component (PFC) material, the correlations presented here can also be used to describe the performance of beryllium as a neutron multiplier for a tritium breeding blanket. The performance properties for beryllium are subdivided into two categories: properties which do not change with irradiation damage to the bulk of the material; and properties which are degraded by neutron irradiation. The approach taken in developing properties correlations is to describe the behavior of dense, pressed S-65 beryllium as a function of temperature. As there are essentially no data on the performance of porous and/or irradiated S-65 beryllium, the degradation of properties with as-fabricated porosity and irradiation are determined form the broad data base on S-200F, as well as other types and grades, and applied to S-65 beryllium by scaling factors. The resulting correlations can be used for Be produced by vacuum hot pressing (VHP) and cold-pressing (CP)/sintering(S)/hot-isostatic-pressing(HIP). The performance of plasma-sprayed beryllium is discussed but not quantified

  9. Financial Incentives to Enable Clean Energy Deployment: Policy Overview and Good Practices

    Energy Technology Data Exchange (ETDEWEB)

    Cox, Sadie [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-02-24

    Financial incentives have been widely implemented by governments around the world to support scaled up deployment of renewable energy and energy efficiency technologies and practices. As of 2015, at least 48 countries have adopted financial incentives to support renewable energy and energy efficiency deployment. Broader clean energy strategies and plans provide a crucial foundation for financial incentives that often complement regulatory policies such as renewable energy targets, standards, and other mandates. This policy brief provides a primer on key financial incentive design elements, lessons from different country experiences, and curated support resources for more detailed and country-specific financial incentive design information.

  10. Good Agricultural Practice (GAP -Does It Ensure a Perfect Supply of Medicinal Herbs for Research and Drug Development?

    Directory of Open Access Journals (Sweden)

    P C Leung

    2008-06-01

    Full Text Available Summary: While users of herbal formulae have been disappointed with the lack of uniformity with the quality of herbs provided by the herb suppliers of different standings, they do not have better means of supply.  The tradition of identifying special geographic regions, as being specific for the best supply of certain herbal items is no longer reliable since the large demand for large quantities of quality supply could not be satisfied by limited plantations in those regions. A comprehensive recommendation of agricultural practice: from seedling, planting, fertilizing, harvesting, storage to distribution, can be offered as a compromise.  There is good prospect of an excellent supply of quality herbal products with uniformity, if Good Agricultural Practice (GAP could be practiced and enforced. Although the need for GAP is urgent, and Japan, China and World Health Organization, have one after the other, written up their recommendation, to put GAP into real practice would need special efforts and takes time. GAP in China is particularly difficult, not only because the herbal items involved are of great numbers but because the current practice of growing medicinal herbs, their marketing and distribution, have been counterproductive to the introduction of the new system of GAP. At this stage, GAP will not be able to satisfy the extensive need for quality and uniformity.  Short of the knowledge of the exact, accurate nature of the active components within a herb, there will be no perfect guarantee on the quality supply.  Henceforth, even when GAP becomes a mature practice, what is required for quality control, viz, different levels of authentication, from chemical finger printing to molecular, DNA identification, will remain necessary as cross-checking mechanisms to make sure that uniformity in scientific experiments and drug development could be maintained

  11. INTERACT Management planning for arctic and northern alpine stations - Examples of good practices

    DEFF Research Database (Denmark)

    of the cornerstones in the INTERACT project is the exchange of station management practises between INTERACT station managers. Therefore INTERACT partners have identified topics of importance for station management and described good practises and lessons learned. The resulted in a book about management of arctic...... and northern alpine research stations. In this book station managers share their knowledge and experience gained frommanaging a set of very diverse research stations in very different environmental and climatic settings. The book covers issues like management planning, policies, permit issues, handling...... of visitors, outreach, science plans, data management and education. The target audience for the book is mainly managers of research stations in arctic and alpine areas, but it is our hope that it will also be a useful tool for others being involved in science coordination and logistics....

  12. Low-cost risk reduction strategy for small workplaces: how can we spread good practices?

    Science.gov (United States)

    Kogi, K

    2006-01-01

    Recent advances in health risk reduction approaches are examined based on inter-country networking experiences. A noteworthy progress is the wider application of low-cost improvements to risk reduction particularly in small enterprises and agriculture in both industrially developing and developed countries. This is helped by the readiness of managers and workers to implement these improvements despite many constraints. Typical improvements include mobile racks, simple workstation changes, screening hazards, better welfare facilities and teamwork arrangements. In view of the complex circumstances of work-related health risks, it is important to know whether a low-cost strategy can advance risk reduction practices effectively and what support measures are necessary. It is confirmed that the strategy can overcome related constraints through its advantages. Main advantages lie in (a) the facilitation of improved practices in multiple technical areas, (b) the strengthening of realistic stepwise risk reduction, and (c) the enhanced multiplier effects through training of local trainers. Action-oriented risk assessment tools, such as action checklists and low-cost improvement guides, can encourage risk-reducing measures adjusted to each local situation. It is suggested to spread the low-cost risk reduction strategy for improving small workplaces in diversified settings with the support of these locally tailored tools.

  13. Low-cost risk reduction strategy for small workplaces: how can we spread good practices?

    Science.gov (United States)

    Kogi, K

    2006-01-01

    Recent advances in health risk reduction approaches are examined based on inter-country networking experiences. A noteworthy progress is the wider application of low-cost improvements to risk reduction particularly in small enterprises and agriculture in both industrially developing and developed countries. This is helped by the readiness of managers and workers to implement these improvements despite many constraints. Typical improvements include mobile racks, simple workstation changes, screening hazards, better welfare facilities and teamwork arrangements. In view of the complex circumstances of work-related health risks, it is important to know whether a low-cost strategy can advance risk reduction practices effectively and what support measures are necessary. It is confirmed that the strategy can overcome related constraints through its advantages. Main advantages lie in (a) the facilitation of improved practices in multiple technical areas, (b) the strengthening of realistic stepwise risk reduction, and (c) the enhanced multiplier effects through training of local trainers. Action-oriented risk assessment tools, such as action checklists and low-cost improvement guides, can encourage risk-reducing measures adjusted to each local situation. It is suggested to spread the low-cost risk reduction strategy for improving small workplaces in diversified settings with the support of these locally tailored tools. PMID:17017363

  14. Good practices for a literature survey are not followed by authors while preparing scientific manuscripts

    CERN Document Server

    Amancio, D R; Oliveira, O N; Costa, L da F

    2010-01-01

    The number of citations received by authors in scientific journals has become a major parameter to assess individual researchers and the journals themselves through the impact factor. A fair assessment therefore requires that the criteria for selecting references in a given manuscript should be unbiased with respect to the authors or the journals cited. In this paper, we advocate that authors should follow two mandatory principles to select papers (later reflected in the list of references) while studying the literature for a given research: i) consider similarity of content with the topics investigated, lest very related work should be reproduced or ignored; ii) perform a systematic search over the network of citations including seminal or very related papers. We use formalisms of complex networks for two datasets of papers from the arXiv repository to show that neither of these two criteria is fulfilled in practice.

  15. An Electronic Mail List for a Network of Family Practice Residency Programs: A Good Idea?

    Directory of Open Access Journals (Sweden)

    Jodi Summers Holtrop

    2001-08-01

    Full Text Available The use of an electronic mailing list as a means of communication among faculty in a network of university-affiliated family practice residency programs was evaluated. Faculty were automatically subscribed to the list by the list owner. Messages were tracked for one year and a written evaluation survey was sent. Ninety two messages were sent, with 52% of the messages being posted information. While most (65% survey respondents reported reading 61% or more of the messages, with only 33% ever actually posted at least one message to the list. Given that faculty were automatically subscribed and that there were only 84 total members, the list may have failed to reach a critical mass of active participants. It is concluded that an email list for network faculty did not function as an online discussion group, although it was extremely beneficial as a way of posting information to affiliated residency faculty.

  16. Study tour: welcome to 11 european cities. Exchanges of good practice

    Energy Technology Data Exchange (ETDEWEB)

    Anderson-Pejovic, D.; Schilken, P.; Vallar, J.P.

    2001-11-01

    On-site visits, information, meetings with players engaged in practical actions and exchanges of experience: eleven European cities organize visits of about forty sites or installations which include: energy efficient and high environmental quality buildings and districts, cogeneration and tri-generation installations, new technologies such as the fuel cell or the Stirling engine, bike-stations or tram-train stations within the scope of innovative mobility policies, low energy consumption equipment, renewable energy installations, solar buildings, hydro-electric or photovoltaic power stations, wind farms.This document presents a typical two day's visit for the following cities: Amersfoort/Utrecht, Barcelona, Frankfurt, Freiburg, Grenoble, Hannover, Heidelberg, Lausanne, London, Montpellier, Saarbrucken. (J.S.)

  17. Making sense of how physician preceptors interact with medical students: discourses of dialogue, good medical practice, and relationship trajectories.

    Science.gov (United States)

    van der Zwet, J; Dornan, T; Teunissen, P W; de Jonge, L P J W M; Scherpbier, A J J A

    2014-03-01

    Work based learning and teaching in health care settings are complex and dynamic. Sociocultural theory addresses this complexity by focusing on interaction between learners, teachers, and their environment as learners develop their professional identity. Although social interaction between doctors and students plays a crucial role in this developmental process, socio-cultural research from the perspective of doctors is scarce. We performed discourse analysis on seven general practitioners' audio diaries during a 10-week general practice clerkship to study how they gave shape to their interaction with their students. Examination of 61 diary-entries revealed trajectories of developing relationships. These trajectories were initiated by the way respondents established a point of departure, based on their first impression of the students. It continued through the development of dialogue with their student and through conceptualizations of good medical practice. Such conceptualizations about what was normal in medical and educational practice enabled respondents to recognize qualities in the student and to indirectly determine students' desired learning trajectory. Towards the end, discursive turns in respondents' narratives signaled development within the relationship. This became evident in division of roles and positions in the context of daily practice. Although respondents held power in the relationships, we found that their actions depended strongly on what the students afforded them socially. Our findings address a gap in literature and could further inform theory and practice, for example by finding out how to foster constructive dialogue between doctors and students, or by exploring different discourses among learners and teachers in other contexts.

  18. Barriers and enablers to good communication and information-sharing practices in care planning for chronic condition management.

    Science.gov (United States)

    Lawn, Sharon; Delany, Toni; Sweet, Linda; Battersby, Malcolm; Skinner, Timothy

    2015-01-01

    Our aim was to document current communication and information-sharing practices and to identify the barriers and enablers to good practices within the context of care planning for chronic condition management. Further aims were to make recommendations about how changes to policy and practice can improve communication and information sharing in primary health care. A mixed-method approach was applied to seek the perspectives of patients and primary health-care workers across Australia. Data was collected via interviews, focus groups, non-participant observations and a national survey. Data analysis was performed using a mix of thematic, discourse and statistical approaches. Central barriers to effective communication and information sharing included fragmented communication, uncertainty around client and interagency consent, and the unacknowledged existence of overlapping care plans. To be most effective, communication and information sharing should be open, two-way and inclusive of all members of health-care teams. It must also only be undertaken with the appropriate participant consent, otherwise this has the potential to cause patients harm. Improvements in care planning as a communication and information-sharing tool may be achieved through practice initiatives that reflect the rhetoric of collaborative person-centred care, which is already supported through existing policy in Australia. General practitioners and other primary care providers should operationalise care planning, and the expectation of collaborative and effective communication of care that underpins it, within their practice with patients and all members of the care team. To assist in meeting these aims, we make several recommendations.

  19. The good, the bad and the 'not so bad': reflecting on moral appraisal in practice.

    Science.gov (United States)

    Begley, Ann Marie

    2011-03-01

    The aim of this study is to facilitate reflection on the moral merit of practitioners in various contexts. Insight is gained from Aristotelian and Kantian accounts of moral character and an original framework for reflection is presented as an adjunct to ethical theory and principles considered when appraising others. In relation to states of character, there is an irreconcilable difference between Kantian (deontic) and Aristotelian (aretaic) conceptions of the nature of full virtue (excellence of character), but at the same time it can be argued that in relation to practice their approaches complement each other. It is also argued that in relation to caring for the vulnerable, Aristotle's conception of full virtue is more compelling than Kant's. On the other hand, Kant's notion of self-serving action is important in nursing and it therefore needs to be considered when reflecting on professional conduct. The conclusion reached is that Aristotelian and Kantian accounts of character appraisal should be used in a combined approach to moral appraisal. This approach draws on the accounts of both philosophers and offers valuable insight into moral character, professional conduct and, in a more formal setting, fitness to practise. PMID:21281392

  20. Energy efficiency in the Southern and Eastern Mediterranean countries - Overview of policies and good practices

    International Nuclear Information System (INIS)

    experiences and know-how should lead states to harmonize increasingly their practices: the most promising measures at the national level may be adopted by other countries and sometimes extended to other neighboring countries. These exchanges of best practices and their development promote also the achievement of the region's objectives of energy efficiency and reduction of greenhouse gas emissions. To achieve these objectives, a reinforced regional cooperation is necessary: its foundations are based on knowledge sharing and technology transfer in the methods, programs and equipments, as energy conservation is an area that is particularly suitable. Similarly, an intensified South-South cooperation will further advance it faster. Indeed, the many available instruments are used differently according to the country, depending on the particularities of each. The economic structure may, for example, explain differences in the implementation of certain measures, with a concentration on the most greenhouse gas emitting sectors, which are not the same from one country to another. The energy - producing or totally dependent countries - and political - more or less liberal governments - situations may also have an influence on the instruments. Of course, this document does not intend to be exhaustive. To present the most illustrative measures, it is structured in meaningful economic sectors in terms of energy efficiency policies, resulting in a division into six themes, each corresponding to a chapter: building, efficient equipment, industry, transport, sustainable urban development and cross-cutting measures. They are preceded by a general chapter with the policies and key figures of energy efficiency in the Mediterranean. In addition, insights are provided on a specific ten of measures of particular interest, selected according to criteria such as energy impact, the consistency of their implementation, their financing mode and their reproducibility where proper evaluation has been

  1. Investigation of beryllium/steam interaction

    Energy Technology Data Exchange (ETDEWEB)

    Chekhonadskikh, A.M.; Vurim, A.D.; Vasilyev, Yu.S.; Pivovarov, O.S. [Inst. of Atomic Energy National Nuclear Center of the Republic of Kazakstan Semipalatinsk (Kazakhstan); Shestakov, V.P.; Tazhibayeva, I.L.

    1998-01-01

    In this report program on investigations of beryllium emissivity and transient processes on overheated beryllium surface attacked by water steam to be carried out in IAE NNC RK within Task S81 TT 2096-07-16 FR. The experimental facility design is elaborated in this Report. (author)

  2. Modeling of hydrogen interactions with beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Longhurst, G.R. [Lockheed Martin Idaho Technologies Co., Idaho Falls, ID (United States)

    1998-01-01

    In this paper, improved mathematical models are developed for hydrogen interactions with beryllium. This includes the saturation effect observed for high-flux implantation of ions from plasmas and retention of tritium produced from neutronic transmutations in beryllium. Use of the models developed is justified by showing how they can replicated experimental data using the TMAP4 tritium transport code. (author)

  3. Production of good manufacturing practice-grade human umbilical cord blood-derived mesenchymal stem cells for therapeutic use.

    Science.gov (United States)

    Van Pham, Phuc; Phan, Ngoc Kim

    2015-01-01

    Human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) are multipotent stem cells that can be differentiated into several specific cell types such as adipocytes, osteoblasts, and chondroblasts. They also were demonstrated to trans-differentiate into other cell lineages such as muscle cells and neurons. Thus, they are considered a promising stem cell source for therapeutic use. Here, we describe a method for production of good manufacturing practice-grade human UCB-MSCs for therapeutic use. The obtained UCB-MSCs are free of allogenous or xenogenous proteins. In addition, these MSCs could maintain the MSC phenotype in long-term culture.

  4. Radiation decontamination of pharmaceutical raw materials as an integral part of the good pharmaceutical manufacturing practice (GPMP)

    International Nuclear Information System (INIS)

    The microbiological quality of many raw materials used in the manufacture of pharmaceuticals and adjuvants often fails to meet the standards set by the pharmaceutical industry. Raw materials of biological provenience are particularly susceptible to contamination. This work describes the present situation regarding the microbial load of corn starch. Given the accepted microbiological criteria, irradiation treatment is proposed as integral to Good Pharmaceutical Manufacturing Practice (GPMP). The use of total viable count as a guide for specifying microbial limits for non-sterile materials is supported. Criteria for the choice of dose are discussed. (author)

  5. Performance-based risk-sharing arrangements-good practices for design, implementation, and evaluation: report of the ISPOR good practices for performance-based risk-sharing arrangements task force.

    Science.gov (United States)

    Garrison, Louis P; Towse, Adrian; Briggs, Andrew; de Pouvourville, Gerard; Grueger, Jens; Mohr, Penny E; Severens, J L Hans; Siviero, Paolo; Sleeper, Miguel

    2013-01-01

    There is a significant and growing interest among both payers and producers of medical products for agreements that involve a "pay-for-performance" or "risk-sharing" element. These payment schemes-called "performance-based risk-sharing arrangements" (PBRSAs)-involve a plan by which the performance of the product is tracked in a defined patient population over a specified period of time and the amount or level of reimbursement is based on the health and cost outcomes achieved. There has always been considerable uncertainty at product launch about the ultimate real-world clinical and economic performance of new products, but this appears to have increased in recent years. PBRSAs represent one mechanism for reducing this uncertainty through greater investment in evidence collection while a technology is used within a health care system. The objective of this Task Force report was to set out the standards that should be applied to "good practices"-both research and operational-in the use of a PBRSA, encompassing questions around the desirability, design, implementation, and evaluation of such an arrangement. This report provides practical recommendations for the development and application of state-of-the-art methods to be used when considering, using, or reviewing PBRSAs. Key findings and recommendations include the following. Additional evidence collection is costly, and there are numerous barriers to establishing viable and cost-effective PBRSAs: negotiation, monitoring, and evaluation costs can be substantial. For good research practice in PBRSAs, it is critical to match the appropriate study and research design to the uncertainties being addressed. Good governance processes are also essential. The information generated as part of PBRSAs has public good aspects, bringing ethical and professional obligations, which need to be considered from a policy perspective. The societal desirability of a particular PBRSA is fundamentally an issue as to whether the cost of

  6. Good practices in development of advanced assembly/core calculation methods and implementations of AEGIS/SCOPE2

    International Nuclear Information System (INIS)

    This paper reviews the history of development of AEGIS/SCOPE2, an advanced in-core fuel management code for PWRs. The initial project, development of a proto-type code, was started in 1996 as a feasibility study of the advanced calculation method/algorithm for advanced computation environments such as distributed parallel computers like PC-clusters which are commonly used nowadays. With success of development of the prototype code, a production-level advanced core calculation code, SCOPE2, was developed followed by AEGIS, an advanced assembly calculation code. These codes have been developed on the basis of the object-oriented programming approach and the agile software development. The authors extracted the key factors for success of the project as good practices from the viewpoint of code design, implementation, project management and verification and validation. Those practices are universal and may be applicable to any projects in the future. (author)

  7. An Integrated Reclamation Scheme to Ensure Good Mining and Mineral Processing Practices in the Niger Delta Area of Nigeria

    Directory of Open Access Journals (Sweden)

    Opafunso Zacheus

    2012-05-01

    Full Text Available This study examines the environmental conditions of mining and mineral processing sites in the Niger Delta Area of Nigeria with special reference to Ondo State, Nigeria. For the purpose of the study, field data were collected on the location, locality, mining status and environmental conditions of solid mineral deposits in the states that make up the Niger Delta area of Nigeria. Hand-held Global Positioning System (GPS receivers were used to determine the location of each site visited. Physical assessment of the environmental degradation as a result of oil and gas exploitation and unfriendly mining and mineral processing practices was done. The area was characterized by great biological diversity with sensitive and fragile ecosystem resulting from dangerous mining and mineral processing practices. To ensure good mining and mineral processing in the area, an integrated reclamation scheme has been developed.

  8. Energy efficiency in the European Union: overview of policies and good practices

    International Nuclear Information System (INIS)

    The world is facing increasing energy prospects and stakes, in terms of energy supply security and safety, environmental impact as well as economic and social costs. In Europe, these fast-growing concerns have led to the adoption of new energy efficiency policies at national and European levels: legislation, regulations, institutional measures, awareness-raising and training campaigns, financial incentives, investment schemes, etc. As in other sectors and at each stage of European development, knowledge and experience feedback drive the Member States towards a growing harmonization of national policies: the most encouraging national measures may be adopted by other countries and even implemented at a European level. The valorization and exchange of best practices therefore contributes to the fulfilment of European commitments on energy efficiency and greenhouse gas emissions reduction. All these schemes are integrally part of a common European energy policy to be applied to energy production, transportation and distribution - the supply side - as well as to all social and economic activities which make up the demand side, and which is the subject of this document. The presentation hereafter provides an overview of energy efficiency policies and programs implemented in the European Union and in the Member States. It shows the diversity of available means of action and strategic choices within the different countries whilst highlighting the most innovative and significant measures. The various tools available are of course used in different ways in each country depending on their characteristics. Economic structure, for example, can explain the differences in the implementation of certain measures as it results in concentrating on the sectors which produce the most greenhouse gases - and which differ from one country to another. Energy balances -energy-producing countries or energy-dependent countries - and political contexts - with more or less liberal governments

  9. Assessment of LANL beryllium waste management documentation

    International Nuclear Information System (INIS)

    The objective of this report is to determine present status of the preparation and implementation of the various high priority documents required to properly manage the beryllium waste generated at the Laboratory. The documents being assessed are: Waste Acceptance Criteria, Waste Characterization Plan, Waste Certification Plan, Waste Acceptance Procedures, Waste Characterization Procedures, Waste Certification Procedures, Waste Training Procedures and Waste Recordkeeping Procedures. Beryllium is regulated (as a dust) under 40 CFR 261.33 as ''Discarded commercial chemical products, off specification species, container residues and spill residues thereof.'' Beryllium is also identified in the 3rd thirds ruling of June 1, 1990 as being restricted from land disposal (as a dust). The beryllium waste generated at the Laboratory is handled separately because beryllium has been identified as a highly toxic carcinogenic material

  10. BERYLLIUM MEASUREMENT IN COMMERCIALLY AVAILABLE WET WIPES

    Energy Technology Data Exchange (ETDEWEB)

    Youmans-Mcdonald, L.

    2011-02-18

    Analysis for beryllium by fluorescence is now an established method which is used in many government-run laboratories and commercial facilities. This study investigates the use of this technique using commercially available wet wipes. The fluorescence method is widely documented and has been approved as a standard test method by ASTM International and the National Institute for Occupational Safety and Health (NIOSH). The procedure involves dissolution of samples in aqueous ammonium bifluoride solution and then adding a small aliquot to a basic hydroxybenzoquinoline sulfonate fluorescent dye (Berylliant{trademark} Inc. Detection Solution Part No. CH-2) , and measuring the fluorescence. This method is specific to beryllium. This work explores the use of three different commercial wipes spiked with beryllium, as beryllium acetate or as beryllium oxide and subsequent analysis by optical fluorescence. The effect of possible interfering metals such as Fe, Ti and Pu in the wipe medium is also examined.

  11. Beryllium for fusion application - recent results

    Science.gov (United States)

    Khomutov, A.; Barabash, V.; Chakin, V.; Chernov, V.; Davydov, D.; Gorokhov, V.; Kawamura, H.; Kolbasov, B.; Kupriyanov, I.; Longhurst, G.; Scaffidi-Argentina, F.; Shestakov, V.

    2002-12-01

    The main issues for the application of beryllium in fusion reactors are analyzed taking into account the latest results since the ICFRM-9 (Colorado, USA, October 1999) and presented at 5th IEA Be Workshop (10-12 October 2001, Moscow Russia). Considerable progress has been made recently in understanding the problems connected with the selection of the beryllium grades for different applications, characterization of the beryllium at relevant operational conditions (irradiation effects, thermal fatigue, etc.), and development of required manufacturing technologies. The key remaining problems related to the application of beryllium as an armour in near-term fusion reactors (e.g. ITER) are discussed. The features of the application of beryllium and beryllides as a neutron multiplier in the breeder blanket for power reactors (e.g. DEMO) in pebble-bed form are described.

  12. The Ideas of God, Good and Evil in the Refigured Yoga Practices in Metropolitan area of Buenos Aires city

    Directory of Open Access Journals (Sweden)

    Mercedes Saizar

    2011-12-01

    Full Text Available Yoga is a widespread therapeutic option; it is the most popular among the oriental rooted medicines, what is more, is accepted and recommended by biomedical doctors like a complementary medicine. Currently, in a context of alternatives therapies offer, yoga appears like one of the disciplines which certain individual uses at least once in their ways of health search. The variety of options, cost and modality of the practice, the appropriation and acceptance on part of dissimilar groups, the proposal of a delicate physical exercise of the body, the compatibility that users find between their system of beliefs and the proposals of this discipline with the possibility of enjoying their benefits without adopting a new life-style, has positioned the practice of yoga as a popular choice and possible way of initiation in other searches associated to the context of the New Age. In this sense, from the point of view of the social actors, yoga is understood as a medicine that include very diverse practices, from a diet to the handling of the altered states of consciousness, from the mobilization of energies through the accomplishment of asanas to a very disclosed and well-known technique as gymnastics yoga. The process of appropriation of the Eastern practices, including yoga, has implied a phenomenon of re-meaning of the main concepts and Eastern structures of thought - aura, chakra, atman, purusha, karma, Brahma, dharma- in terms of values, categories and western experiences of the religions and philosophical currents, those that add essential dichotomies to these conceptions like good and evil, sin and punishment, spiritual and material, radically transforming the Eastern knowledge. In this opportunity, our interests focuses on investigate the slight knowledge of God, Good and Evil, that emerge from such appropriation processes that cross the yoga practices, conceiving it like a totality, in the context of the alternative practices and the phenomena of

  13. Technical issues for beryllium use in fusion blanket applications

    International Nuclear Information System (INIS)

    Beryllium is an excellent non-fissioning neutron multiplier for fusion breeder and fusion electric blanket applications. This report is a compilation of information related to the use of beryllium with primary emphasis on the fusion breeder application. Beryllium resources, production, fabrication, properties, radiation damage and activation are discussed. A new theoretical model for beryllium swelling is presented

  14. Utilization of the seven principles for good practice in undergraduate education in general chemistry by community college instructors

    Science.gov (United States)

    Panther Bishoff, Jennifer

    In recent years, higher education has undergone many changes. The advent of assessment, accountability, and a newfound focus on teaching have required faculty to examine how they are teaching. Administrators and faculty are beginning to recognize that learning is not a "one size fits all" enterprise. To this end, Chickering and Gamson developed an inventory that examined faculty utilization of the Seven Principles of Good Practice in Undergraduate Education. The seven principles included by the authors included faculty-student interaction, cooperative learning, active learning, giving prompt feedback, emphasizing time on task, communicating high expectations, and respecting diverse talents and ways of learning. It was determined by Chickering and Gamson, as well as many other researchers, that these seven principles were hallmarks of successful undergraduate education. Community colleges are important institutions to study, as many students begin their higher education at two-year colleges. Most students are also required to take one or more science classes for their general education requirements; therefore, many students must take at least one general chemistry course. Both community colleges and chemistry are rarely studied in literature, which makes this study important. Community college general chemistry instructors were surveyed using an online version of Chickering and Gamson's Faculty Inventory for the Seven Principles of Good Practice in Undergraduate Education. Responses were analyzed, and it was discovered that not only did instructors utilize the principles to a different extent, but there were also differences between genders as well as between the specific actions related to each principle.

  15. Preliminary proposal for a beryllium technology program for fusion applications

    International Nuclear Information System (INIS)

    The program was designed to provide the answers to the critical issues of beryllium technology needed in fusion blanket designs. The four tasks are as follows: (1) Beryllium property measurements needed for fusion data base. (2) Beryllium stress relaxation and creep measurements for lifetime modelling calculations. (3) Simplified recycle technique development for irradiated beryllium. (4) Beryllium neutron multiplier measurements using manganese bath absolute calibration techniques

  16. Good Wetland Agricultural Practices

    NARCIS (Netherlands)

    Hengsdijk, H.; Zingstra, H.L.

    2009-01-01

    Within the Guiding Agriculture Wetland Interaction (GAWI) project the Driver!Pressure!State! Impact!Response (DPSIR) approach has been adopted to describe and analyse agriculture!wetland interactions. The DPSIR approach provides a consistent framework to analyse the complex causal chain among driver

  17. Recommended design correlations for S-65 beryllium

    International Nuclear Information System (INIS)

    The properties of tritium and helium behavior in irradiated beryllium are reviewed, along with the thermal-mechanical properties needed for ITER design analysis. Correlations are developed to describe the performance of beryllium in a fusion reactor environment. While this paper focuses on the use of beryllium as a plasma-facing component (PFC) material, the correlations presented here can also be used to describe the performance of beryllium as a neutron multiplier for a tritium breeding blanket. The performance properties for beryllium are subdivided into two categories: properties which do not change with irradiation damage to the bulk of the material; and properties which are degraded by neutron irradiation. The irradiation-independent properties described within are: thermal conductivity, specific heat capacity, thermal expansion, and elastic constants. Irradiation-dependent properties include: yield strength, ultimate tensile strength, plastic tangent modulus, uniform and total tensile elongation, thermal and irradiation-induced creep strength, He-induced swelling and tritium retention/release. The approach taken in developing properties correlations is to describe the behavior of dense, pressed S-65 beryllium -- the material chosen for ITER PFC application -- as a function of temperature. As there are essentially no data on the performance of porous and/or irradiated S-65 beryllium, the degradation of properties with as-fabricated porosity and irradiation are determined from the broad data base on S-200F, as well as other types and grades, and applied to S-65 beryllium by scaling factors. The resulting correlations can be used for Be produced by vacuum hot pressing (VHP) and cold-pressing (CP)/sintering(S)/hot-isostatic-pressing (HIP). The performance of plasma-sprayed beryllium is discussed but not quantified

  18. Recommended design correlations for S-65 beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Billone, M.C. [Argonne National Lab., IL (United States)

    1995-09-01

    The properties of tritium and helium behavior in irradiated beryllium are reviewed, along with the thermal-mechanical properties needed for ITER design analysis. Correlations are developed to describe the performance of beryllium in a fusion reactor environment. While this paper focuses on the use of beryllium as a plasma-facing component (PFC) material, the correlations presented here can also be used to describe the performance of beryllium as a neutron multiplier for a tritium breeding blanket. The performance properties for beryllium are subdivided into two categories: properties which do not change with irradiation damage to the bulk of the material; and properties which are degraded by neutron irradiation. The irradiation-independent properties described within are: thermal conductivity, specific heat capacity, thermal expansion, and elastic constants. Irradiation-dependent properties include: yield strength, ultimate tensile strength, plastic tangent modulus, uniform and total tensile elongation, thermal and irradiation-induced creep strength, He-induced swelling and tritium retention/release. The approach taken in developing properties correlations is to describe the behavior of dense, pressed S-65 beryllium -- the material chosen for ITER PFC application -- as a function of temperature. As there are essentially no data on the performance of porous and/or irradiated S-65 beryllium, the degradation of properties with as-fabricated porosity and irradiation are determined from the broad data base on S-200F, as well as other types and grades, and applied to S-65 beryllium by scaling factors. The resulting correlations can be used for Be produced by vacuum hot pressing (VHP) and cold-pressing (CP)/sintering(S)/hot-isostatic-pressing (HIP). The performance of plasma-sprayed beryllium is discussed but not quantified.

  19. Compliance of disposal orbits with the French Space Operations Act: The Good Practices and the STELA tool

    Science.gov (United States)

    Le Fèvre, C.; Fraysse, H.; Morand, V.; Lamy, A.; Cazaux, C.; Mercier, P.; Dental, C.; Deleflie, F.; Handschuh, D. A.

    2014-01-01

    Space debris mitigation is one objective of the French Space Operations Act (FSOA), in line with Inter-Agency Space Debris Coordination Committee (IADC) recommendations, through the removal of non-operational objects from populated regions. At the end of their mission, space objects are to be placed on orbits that will minimize future hazards to space objects orbiting in the same region. The FSOA, which came into force in 2010, ensures that technical risks associated with space activities are properly mitigated. The Act confers CNES a central support role in providing technical expertise to government on regulations dealing with space operations. In order to address the compliance of disposal orbits with the law technical requirements, CNES draws up Good Practices as well as a dedicated tool, Semi-analytic Tool for End of Life Analysis (STELA). The verification of the criteria of the French Space Operations Act requires long term orbit propagation to evaluate the evolution of the orbital elements over long time scales (up to more than 100 years). The Good Practices define the minimum dynamical model required to compute the orbital evolution with sufficient accuracy, and detail key computation hypotheses such as drag and reflecting areas, drag coefficient, reflectivity coefficient, solar activity, atmospheric density model and so on. They also recommend a methodology adapted to each orbit type (LEO, GEO, GTO) to assess the criteria of the French Space Operations Act. The most recent works have concerned GTO, for which some couplings occur between dynamic perturbations. A small change in the initial conditions or in the estimation of the drag effect will significantly change the entrance conditions in resonance areas and thus the orbital evolution. To cope with this difficulty, a statistical method has been developed. This paper gives an overview of the Good Practices for orbit propagation in LEO, GEO and GTO as well as a brief description of the STELA tool. It

  20. Current good manufacturing practice in manufacturing, processing, packing, or holding of drugs; revision of certain labeling controls. Final rule.

    Science.gov (United States)

    2012-03-20

    The Food and Drug Administration (FDA) is amending the packaging and labeling control provisions of the current good manufacturing practice (CGMP) regulations for human and veterinary drug products by limiting the application of special control procedures for the use of cut labeling to immediate container labels, individual unit cartons, or multiunit cartons containing immediate containers that are not packaged in individual unit cartons. FDA is also permitting the use of any automated technique, including differentiation by labeling size and shape, that physically prevents incorrect labeling from being processed by labeling and packaging equipment when cut labeling is used. This action is intended to protect consumers from labeling errors more likely to cause adverse health consequences, while eliminating the regulatory burden of applying the rule to labeling unlikely to reach or adversely affect consumers. This action is also intended to permit manufacturers to use a broader range of error prevention and labeling control techniques than permitted by current CGMPs.

  1. THE ROLE OF GOOD PRACTICES IN THE MANAGEMENT OF ETHICAL PROGRAMS IN HOSPITAL ESTABLISHMENTS. A FURTHER STEP FROM ETHICS COMMITTEES

    Directory of Open Access Journals (Sweden)

    AGHEORGHIESEI (CORODEANU DANIELA-TATIANA

    2012-09-01

    Full Text Available This article is a review of both the functions and roles played by ethics committees in hospital establishments,and respectively of the challenges they are confronted with, in the general context of activities concerned withorganizational ethics. Furthermore, we analyse international good practices, such as they intervene in the organizationof ethical programs, and also the place the committees take up within these programs. Our qualitative research isbased on the analysis of the websites of 144 hospitals from Romania, classified within the first three competence levels,and aims at highlighting the fact that ethics committees do not have sufficient visibility, which is certainly notbeneficial to patients. In this context, our research demonstrates that there is plenty space for improvement in quality ofcare based on ethics program and its tools and the experience of other countries could serve as a viable guide.

  2. UPAYA MENCAPAI AKREDITASI GOOD PHARMACY PRACTICE (GPP PT. KIMIA FARMA APOTEK (STUDI KASUS DI UNIT BISNIS JAYA 2

    Directory of Open Access Journals (Sweden)

    Astrid Dwiastuti

    2015-06-01

    Full Text Available Tulisan ini bertujuan untuk mengindentifikasi, mengukur serta menganalisa kesenjangan yuang terjadi saat implementasi Good Pharmacy Practice (GPP di PT. Kimia Farma Apotek, Unit Bisnis Jaya 2 Business Unit. Selain itu, proses perencanaan aksi dalam rangka pencapaian nilai tertinggi.Metode penelitian yang dilakukan adalah analisa deskripsi kualitatif, pencarian data melalui audit, observasi dan interview. Teknik analisa yang digunakan adalah analisa tulang ikan untuk mendapatkan akar penyebab dan sesi pencerahan dalam rangka perancangan peningkatan aksi perencanaan. Hasil penelitian menunjukkan kesenjangan terjadi disebabkan oleh keterlambatan aktifitas manajemen mutu, siklus PDSA, seperti perancangan tata letak dan infrastruktur farmasi, sosialisasi tentang GPP, pembahasan deskripsi kerja, audit hasil evaluasi dan peningkatan kerja secara komprehensif. Rekomendasi rencana aksi untuk sebagai sebuah upaya improvisasi juga disampaikan pada bagian akhir dari tulisan ini.

  3. Good clinical practice guide for opioids in pain management: the three Ts - titration (trial, tweaking (tailoring, transition (tapering

    Directory of Open Access Journals (Sweden)

    Flaminia Coluzzi

    2016-06-01

    Full Text Available ABSTRACT BACKGROUND AND OBJECTIVES: Achieving good clinical practice in the use of opioids as part of a comprehensive pain management regimen can face significant challenges. Despite guidelines from governmental and pain society/organization sources, there are still significant hurdles. A review of some basic tenets of opioid analgesia based on current published knowledge and experiences about this important healthcare imperative is warranted. CONTENT: Consistent with guidelines, the literature supports using the lowest total opioid dose that provides adequate pain control with the fewest adverse effects. Titration (or trial during opioid initiation is a way of starting low and going slow (and assessing the appropriateness of a specific opioid and formulation. Recognizing that multiple factors contribute to an individual's personal experience of pain, the physical, psychological, social, cultural, spiritual, pharmacogenomic, and behavioral factors of the individual patient should be taken into account (tweaking, or tailoring. Finally, for those patients for whom transition (tapering from opioid is desired, doing so too rapidly can have negative consequences and minimization of problems during this step can be achieved by proper tapering. CONCLUSION: We conclude that a simultaneously aggressive, yet conservative, approach is advocated in the literature in which opioid therapy is divided into three key steps (the 3 T's: titration (or trial, tweaking (or tailoring, and transition (or tapering. Establishment of the 3 T's along with the application of other appropriate good medical practice and clinical experience/judgment, including non-pharmacologic approaches, can assist healthcare providers in the effort to achieve optimal management of pain.

  4. Using spirometry results in occupational medicine and research: Common errors and good practice in statistical analysis and reporting

    Directory of Open Access Journals (Sweden)

    Wagner N

    2006-01-01

    Full Text Available Spirometry appears to be a simple and inexpensive method to measure disorders of the respiratory tract. In reality however, a simple spirometry test requires knowledge and skill to correctly conduct and evaluate the test and its results. This review addresses common misunderstandings in using, evaluating and reporting spirometry results in Occupational Health practice, clinical medicine and research. Results of spirometry need to be evaluated in relation to reference values. The factory medical officer has to decide first whether the test was technically correctly executed and is acceptable for medical interpretation. The next step is to compare results of the individual to published reference values. A 10% reduction of reference values for North Indians and Pakistanis and a 12 to 13% reduction for South Indians is recommended when Caucasian reference tables are used. In occupational health practice the worker′s spirometry performance over time needs to be considered. Common errors in reporting summarized results, for instance from groups of workers, are the incorrect use of tests of significance and incorrect presentation of aggregated spirometry results. The loss of respiratory function is recommended as an indicator of difference between two groups. That way, early changes in function can seen without waiting for a drop of function below the usually used 80%-of-predicted limit. This procedure increases the sensitivity of medical surveillance. In research the more precise Lower Limit of Normal should be calculated and used. Correct reference equations, good patient coaching, decision on the technical quality (acceptability of each spirometry test and critical re-evaluation of the machine′s readout are essential parts of a correct spirometry test. A good understanding how results are calculated is crucial for further statistical evaluation.

  5. POLÍTICAS EDUCATIVAS, BUENAS PRÁCTICAS Y TIC EDUCATIONAL POLICIES AND GOOD PRACTICES WITH ICT IN ANDALUSIA REGION

    Directory of Open Access Journals (Sweden)

    Juan de Pablos Pons

    2010-02-01

    Full Text Available Esta aportación está vinculada a la difusión de los resultados de un proyecto de investigación titulado “Políticas educativas autonómicas y sus efectos sobre la innovación pedagógica en el uso de las TIC en los centros escolares”, que se ha desarrollado en el marco del Plan Nacional de I+D 2004-2007. El trabajo se centra en el análisis del discurso que explicita las políticas educativas en Andalucía, dirigidas a la incorporación de las TIC en el sistema educativo. El estudio realizado permite, por un lado, conocer y detallar los conceptos implícitos en las mismas respecto a “buenas prácticas” con TIC, innovación educativa con TIC, y usos de las TIC, y por otro, determinar los principales  ámbitos de incidencia de la intervención política, así como los programas de incentivación relacionados con la innovación y buenas prácticas con TIC.This contribution is linked to a research project entitled "Education policies and their effects on regional educational innovation in the use of ICT in schools", which has been developed under the National Program Research and Development 2004-2007. The work is focused on discourse analysis about incorporating Andalusian ICT in the educational system. The study allows to understand the concepts involved in the same relation to good practice with ICT education with ICT innovation and ICT use, and to determine the main areas where the political intervention and incentive programs related to innovation and good practice with ICT.

  6. European Commission against Racism and Intolerance/ECRI (Hrsg.): Examples of good practices - Specialised bodies to combat racism, xenophobia, antisemitism and intolerance at national level / [Rezension

    OpenAIRE

    2006-01-01

    rezensiertes Werk: European Commission against Racism and Intolerance/ECRI (Hrsg.): Examples of good practices - Specialised bodies to combat racism, xenophobia, antisemitism and intolerance at national level, Januar 2006.

  7. Lithium-Beryllium-Boron : Origin and Evolution

    OpenAIRE

    Vangioni-Flam, Elisabeth; Casse, Michel; Audouze, Jean

    1999-01-01

    The origin and evolution of Lithium-Beryllium-Boron is a crossing point between different astrophysical fields : optical and gamma spectroscopy, non thermal nucleosynthesis, Big Bang and stellar nucleosynthesis and finally galactic evolution. We describe the production and the evolution of Lithium-Beryllium-Boron from Big Bang up to now through the interaction of the Standard Galactic Cosmic Rays with the interstellar medium, supernova neutrino spallation and a low energy component related to...

  8. Wavefunction and energy of the 1s22sns configuration in a beryllium atom

    Institute of Scientific and Technical Information of China (English)

    Huang Shi-Zhong; Ma Kun; Yu Jia-Ming; Liu Fen

    2008-01-01

    A new set of trial functions for 1s22sns configurations in a beryllium atom is suggested.A Mathematica program baaed on the variational method is developed to calculate the wavefunctions and energies of 1s22sns (n=3-6)configurations in a beryllium atom.Non-relativistic energy,polarization correction and relativistic correction which include mass correction,one- and two-body Darwin corrections,spin-spin contact interaction and orbit-orbit interaction,are calculated respectively.The results are in good agreement with experimental data.

  9. Interaction of beryllium and hydrogen isotopes

    International Nuclear Information System (INIS)

    It has been considered that in the plasma nuclear fusion experimental devices of magnetic field confinement type, in order to reduce the energy loss due to bremsstrahlung, the use of the plasma-facing materials (PFM) of low atomic number like carbon is indispensable at present. Attention is paid to beryllium which is one of the PFMs, and its effectiveness was rocognized by the practical use in JET. When Be is considered as a PFM, it is necessary to accumulate many data on the diffusion, dissolution, permeation and surface recoupling of hydrogen isotopes, which regulate the recycling and inventory of deuterium and tritium fuel, and the relation of these factors with the physical and chemical states of Be. In this research, as the first phase of understanding the characteristics of Be as a PFM, the change of the surface condition by heating Be was investigated by X-ray photoelectron spectroscopy, and the chemical form of the Be-related substances emitted from the surface by argon or deuterium ion sputtering and their thermal behavior were measured by secondary ion mass spectrometry. The sample, the measurement and the results are reported. The diversified secondary ions of Be, Be cluster, Be oxide, hydroxide, hydride and deuteride were observed by the measurement, and their features are shown. (K.I.)

  10. Tritium release from neutron irradiated beryllium pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Scaffidi-Argentina, F.; Werle, H. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reactortechnik

    1998-01-01

    One of the most important open issues related to beryllium for fusion applications refers to the kinetics of the tritium release as a function of neutron fluence and temperature. The EXOTIC-7 as well as the `Beryllium` experiments carried out in the HFR reactor in Petten are considered as the most detailed and significant tests for investigating the beryllium response under neutron irradiation. This paper reviews the present status of beryllium post-irradiation examinations performed at the Forschungszentrum Karlsruhe with samples from the above mentioned irradiation experiments, trying to elucidate the tritium release controlling processes. In agreement with previous studies it has been found that release starts at about 500-550degC and achieves a maximum at about 700-750degC. The observed release at about 500-550degC is probably due to tritium escaping from chemical traps, while the maximum release at about 700-750degC is due to tritium escaping from physical traps. The consequences of a direct contact between beryllium and ceramics during irradiation, causing tritium implanting in a surface layer of beryllium up to a depth of about 40 mm and leading to an additional inventory which is usually several times larger than the neutron-produced one, are also presented and the effects on the tritium release are discussed. (author)

  11. Solid state bonding of beryllium-copper for an ITER first wall application

    International Nuclear Information System (INIS)

    Several different joint assemblies were evaluated in support of a manufacturing technology for diffusion bonding a beryllium armor tile to a copper alloy heat sink for fusion reactor applications. Because beryllium reacts with all but a few elements to form intermetallic compounds, this study considered several different surface treatments as a means of both inhibiting these reactions and promoting a good diffusion bond between the two substrates. All diffusion bonded assemblies used aluminum or an aluminum-beryllium composite (AlBeMet-150) as the interfacial material in contact with beryllium. In most cases, explosive bonding was utilized as a technique for joining the copper alloy heat sink to an aluminum or AlBeMet-150 substrate, which was subsequently diffusion bonded to an aluminum coated beryllium tile. In this approach, a 250 μm thick titanium foil was used as a diffusion barrier between the copper and aluminum to prevent the formation of Cu-Al intermetallic phases. In all cases, a hot isostatic pressing (HIP) furnace was used in conjunction with canned assemblies in order to minimize oxidation and apply sufficient pressure on the assembly for excellent metal-to-metal contact and subsequent bonding. Several different processing schedules were evaluated during the course of this study; bonded assemblies were produced that failed outside the bond area indicating a 100% joint efficiency. (author)

  12. Solid state bonding of beryllium-copper for an ITER first wall application

    Energy Technology Data Exchange (ETDEWEB)

    Odegard, B.C. Jr.; Cadden, C.H. [Sandia National Labs., Livermore, CA (United States)

    1998-01-01

    Several different joint assemblies were evaluated in support of a manufacturing technology for diffusion bonding a beryllium armor tile to a copper alloy heat sink for fusion reactor applications. Because beryllium reacts with all but a few elements to form intermetallic compounds, this study considered several different surface treatments as a means of both inhibiting these reactions and promoting a good diffusion bond between the two substrates. All diffusion bonded assemblies used aluminum or an aluminum-beryllium composite (AlBeMet-150) as the interfacial material in contact with beryllium. In most cases, explosive bonding was utilized as a technique for joining the copper alloy heat sink to an aluminum or AlBeMet-150 substrate, which was subsequently diffusion bonded to an aluminum coated beryllium tile. In this approach, a 250 {mu}m thick titanium foil was used as a diffusion barrier between the copper and aluminum to prevent the formation of Cu-Al intermetallic phases. In all cases, a hot isostatic pressing (HIP) furnace was used in conjunction with canned assemblies in order to minimize oxidation and apply sufficient pressure on the assembly for excellent metal-to-metal contact and subsequent bonding. Several different processing schedules were evaluated during the course of this study; bonded assemblies were produced that failed outside the bond area indicating a 100% joint efficiency. (author)

  13. Sanitary-hygienic and ecological aspects of beryllium production

    Energy Technology Data Exchange (ETDEWEB)

    Dvinskykh, E.M.; Savchuk, V.V.; Sidorov, V.L.; Slobodin, D.B.; Tuzov, Y.V. [Ulba Metallurgical Plant, Ust-Kamenogorsk (Kazakhstan)

    1998-01-01

    The Report describes An organization of sanitary-hygienic and ecological control of beryllium production at Ulba metallurgical plant. It involves: (1) the consideration of main methods for protection of beryllium production personnel from unhealthy effect of beryllium, (2) main kinds of filters, used in gas purification systems at different process areas, (3) data on beryllium monitoring in water, soil, on equipment. This Report also outlines problems connected with designing devices for a rapid analysis of beryllium in air as well as problems of beryllium production on ecological situation in the town. (author)

  14. Good manufacturing practice production of [(68)Ga]Ga-ABY-025 for HER2 specific breast cancer imaging.

    Science.gov (United States)

    Velikyan, Irina; Wennborg, Anders; Feldwisch, Joachim; Lindman, Henrik; Carlsson, Jörgen; Sörensen, Jens

    2016-01-01

    Therapies targeting human epidermal growth factor receptor type 2 (HER2) have revolutionized breast cancer treatment, but require invasive biopsies and rigorous histopathology for optimal patient stratification. A non-invasive and quantitative diagnostic method such as positron emission tomography (PET) for the pre-therapeutic determination of the presence and density of the HER2 would significantly improve patient management efficacy and treatment cost. The essential part of the PET methodology is the production of the radiopharmaceutical in compliance with good manufacturing practice (GMP). The use of generator produced positron emitting (68)Ga radionuclide would provide worldwide accessibility of the agent. GMP compliant, reliable and highly reproducible production of [(68)Ga]Ga-ABY-025 with control over the product peptide concentration and amount of radioactivity was accomplished within one hour. Two radiopharmaceuticals were developed differing in the total peptide content and were validated independently. The specific radioactivity could be kept similar throughout the study, and it was 6-fold higher for the low peptide content radiopharmaceutical. Intrapatient comparison of the two peptide doses allowed imaging optimization. The high peptide content decreased the uptake in healthy tissue, in particular liver, improving image contrast. The later imaging time points enhanced the contrast. The combination of high peptide content radiopharmaceutical and whole-body imaging at 2 hours post injection appeared to be optimal for routine clinical use.

  15. The Legal Language written in spanish in a sentence and textual perspective: pathology, good practices and alternative versions

    Directory of Open Access Journals (Sweden)

    Maria Angeles Garcia

    2013-12-01

    Full Text Available The purpose of this paper is to present the results of the research which is collected, as a report in the publication: Estudio de campo: lenguaje escrito (MONTOLÍO, 2011a. This is a fieldwork that, in a textual and sentence perspective, assesses the communicative quality of legal documents written in Spanish in Spain. The work brings together examples of linguistic formulations and mechanisms of syntactic-discursive organization of the documents submitted for analysis, which hinder or impede the understanding of the texts by the lay citizen in Law. It also provides examples of good practice, showing cases in which the jurists use a certain writing mechanism correctly and efficiently. Finally, it offers alternative versions to textual fragments with pathological conditions, in order to show that, when properly handled the expressive resources of language and expression can be simplified to make it clearer, the texts become more pleasant and keep the communication between the Administration of justice and citizenship. The research concludes with a proposal of recommendations to achieve a legal transparent language for both legal practitioners and for the citizen, as we also present in this paper.

  16. WHAT’S IN A NAME: The Amateur‘s View of Good Practices in Naming an Online Educational Program

    Directory of Open Access Journals (Sweden)

    Michael J. ROSZKOWSKI

    2013-07-01

    Full Text Available Branding is considered to be particularly important in the marketing of online educational programs. A critical step to establishing the brand is naming the product appropriately. To this end, one can secure the services of professionals or rely on a do-it-yourself approach. The research reported here aimed to identify the features that non-professionals (graduate students consider to be important in the name for an online educational product, and to compare these to the recommendations made by naming professionals (as reported in the literature. A survey directed at current and prospective graduate students at a traditional university asked about the desirability of 16 characteristics in the name of a new line of online courses. The six characteristics that were deemed most critical are (in order of importance: self-explanatory, memorable, easy to pronounce, has appealing associations, suggests/hints at the key features, and short. These are the same features that professionals in the business of creating new product names generally consider as best practices in creating a name. The results show that contrary to the concerns expressed by some practitioners in the naming industry, college-educated individuals who do not create names for a living nonetheless demonstrate an awareness and appreciation for the features of a good name in an Internet-based course delivery system.

  17. Sub-micro level monitoring of beryllium ions with a novel beryllium sensor based on 2,6-diphenyl-4-benzo-9-crown-3-pyridine.

    Science.gov (United States)

    Ganjali, Mohammad Reza; Rahimi-Nasrabadi, Mehdi; Maddah, Bozorgmehr; Moghimi, Abolghasem; Faal-Rastegar, Madjid; Borhany, Shahin; Namazian, Mansour

    2004-07-01

    The 2,6-diphenyl-4-benzo-9-crown-3-pyridine (DPCP) was used as an excellent ionophore in construction of a coated graphite poly(vinyl chloride) (PVC)-based membrane sensor. The best performance was obtained with a membrane composition of 30% poly(vinyl chloride), 60% o-nitrophenyloctyl ether (NPOE), 5% 2,6-diphenyl-4-benzo-9-crown-3-pyridine and 5% sodium tetraphenyl borate (TBP). This sensor shows very good selectivity and sensitivity towards beryllium ion over a wide variety of cations, including alkali, alkaline earth, transition and heavy metal ions. The sensor revealed a great enhancement in selectivity coefficients and sensitivity for beryllium, in comparison with the previously reported beryllium electrodes. The electrode exhibits a Nernstian behavior (with slope of 29.6mV per decade) over a very wide concentration range (1.0x10(-7) to 1.0x10(-1)) with a detection limit of 4.0x10(-8)M (360pgml(-1)). It shows relatively fast response time, in whole concentration range (beryllium in mineral ore.

  18. Beryllium. Health hazards and their control. Pt. 2

    International Nuclear Information System (INIS)

    In this work (continuation of 'Beryllium' series) health hazards, toxic effects, limits of permissible atmospheric contamination and safe exposure to beryllium are described. Guidelines to the design, control operations and hygienic precautions of the working facilities are given. (Author)

  19. Mechanical performance of irradiated beryllium pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Scaffidi-Argentina, F.; Dalle-Donne, M.; Werle, H. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reaktortechnik

    1998-01-01

    For the Helium Cooled Pebble Bed (HCPB) Blanket, which is one of the two reference concepts studied within the European Fusion Technology Programme, the neutron multiplier consists of a mixed bed of about 2 and 0.1-0.2 mm diameter beryllium pebbles. Beryllium has no structural function in the blanket, however microstructural and mechanical properties are important, as they might influence the material behavior under neutron irradiation. The EXOTIC-7 as well as the `Beryllium` experiments carried out in the HFR reactor in Petten are considered as the most detailed and significant tests for investigating it. This paper reviews the present status of beryllium post-irradiation examinations performed at the Forschungszentrum Karlsruhe with samples from these irradiation experiments, emphasizing the effects of irradiation of essential material properties and trying to elucidate the processes controlling the property changes. The microstructure, the porosity distribution, the impurity content, the behavior under compression loads and the compatibility of the beryllium pebbles with lithium orthosilicate (Li{sub 4}SiO{sub 4}) during the in-pile irradiation are presented and critically discussed. Qualitative information on ductility and creep obtained by hardness-type measurements are also supplied. (author)

  20. Scientific Opinion on good modelling practice in the context of mechanistic effect models for risk assessment of plant protection products

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Plant Protection Products and their Residues (PPR

    2014-03-01

    Full Text Available The Panel has interpreted the Terms of Reference as a stepwise analysis of issues relevant to both the development and the evaluation of models to assess ecological effects of pesticides. The regulatory model should be selected or developed to address the relevant specific protection goal. The basis of good modelling practice must be the knowledge of relevant processes and the availability of data of sufficient quality. The opinion identifies several critical steps in order to set models within risk assessment, namely: problem formulation, considering the specific protection goals for the taxa or functional groups of concern; model domain of applicability, which drives the species and scenarios to model; species (and life stage selection, considering relevant life history traits and toxicological/toxicokinetics characteristics of the pesticide; selection of the environmental scenario, which is defined by a combination of abiotic, biotic and agronomic parameters to provide a realistic worst-case situation. Model development should follow the modelling cycle, in which every step has to be fully documented: (i problem definition; (ii model formulation, i.e. design of a conceptual model; (iii model formalisation, in which variables and parameters are linked together into mathematical equations or algorithms; (iv model implementation, in which a computer code is produced and verified; (v model setup, including sensitivity analysis, uncertainty analysis and comparison with observed data, that delivers the regulatory model; (vi prior to actual use in risk assessment, the regulatory model should be evaluated for relevance to the specific protection goals; (vii feedback from risk assessor with possible recommendations for model improvement. Model evaluation by regulatory authorities should consider each step of the modelling cycle: the opinion identifies points of particular attention for the use of mechanistic effect models in pesticide risk assessment

  1. The Clue to Minimizing the Developer-User Divide by Good Practice in Earth and Space Science Informatics

    Science.gov (United States)

    Messerotti, M.

    2009-04-01

    Earth and Space Science research, as well as many other disciplines, can nowadays benefit from advanced data handling techniques and tools capable to significantly relieve the scientist of the burden of data search, retrieval, visualization and manipulation, and to exploit the data information content. Some typical examples are Virtual Observatories (VO) specific to a variety of sub-disciplines but anyway interlinked, a feature intrinsic to the VO architecture, Virtual Globes as advanced 3D selection and visualization interfaces to distributed data repositories, and the Global Earth Observation System of Systems. These information systems are proving also effective in education and outreach activities as they are usable via web interfaces to give access to, to display and to download nonhomogeneous datasets in order to raise the awareness of the students and the public on the relevant disciplines. Despite of that, all of this effective machineries are still poorly used both by the scientific community and by the community active in education and outreach. All such infrastructures are designed and developed according to the state-of-the-art information and computer engineering techniques and are provided with top features such as ontology- and semantics-based data management, and advanced unified web-based interfaces. Anyway, a careful analysis of the issue mentioned above indicates a key aspect that play a major role, i.e., the inadequate interaction with the users' communities during the design, the development, the deployment and the test phases. Even the best technical tool can appear inadequate to the final user when it does not meet the user's requirements in terms of achievable goals and use friendliness. In this work, we consider the user-side features to be taken into account for the optimum exploitation of an information system in the framework of the interaction among the design engineers and the target communities towards the setting of a good practice

  2. Encouraging good antimicrobial prescribing practice: A review of antibiotic prescribing policies used in the South East Region of England

    Directory of Open Access Journals (Sweden)

    Mayon White Richard T

    2001-05-01

    Full Text Available Abstract Background Good prescribing practice has an important part to play in the fight against antimicrobial resistance. Whilst it was perceived that most hospitals and Health Authorities possessed an antibiotic policy, a review of antibiotic policies was conducted to gain an understanding of the extent, quality and usefulness of these policies. Methods Letters were sent to pharmacists in hospitals and health authorities in across the South East region of the National Health Service Executive (NHSE requesting antibiotic policies. data were extracted from the policies to assess four areas; antibiotic specific, condition specific, patient specific issues and underpinning evidence. Results Of a possible 41 hospital trusts and 14 health authorities, 33 trusts and 9 health authorities (HAs provided policies. Both trust and HA policies had a median publication date of 1998 (trust range 1993-99, HA 1994-99. Eleven policies were undated. The majority of policies had no supporting references for the statements made. All policies provided some details on specific antibiotics. Gentamicin and ciprofloxacin were the preferred aminoglycoside and quinolone respectively with cephalosporins being represented by cefuroxime or cefotaxime in trusts and cephradine or cephalexin in HAs. 26 trusts provided advice on surgical prophylaxis, 17 had meningococcal prophylaxis policies and 11 covered methicillin resistant Staphylococcus aureus (MRSA. There was little information for certain groups such as neonates or children, the pregnant or the elderly. Conclusion There was considerable variation in content and quality across policies, a clear lack of an evidence base and a need to revise policies in line with current recommendations.

  3. Health physics manual of good practices for reducing radiation exposure to levels that are as low as reasonably achievable (ALARA)

    International Nuclear Information System (INIS)

    A primary objective of the US Department of Energy (DOE) health physics and radiation protection program has been to limit radiation exposures to those levels that are as low as reasonably achievable (ALARA). As a result, the ALARA concept developed into a program and a set of operational principles to ensure that the objective was consistently met. Implementation of these principles required that a guide be produced. The original ALARA guide was issued by DOE in 1980 to promote improved understanding of ALARA concepts within the DOE community and to assist those responsible for operational ALARA activities in attaining their goals. Since 1980, additional guidance has been published by national and international organizations to provide further definition and clarification to ALARA concepts. As basic ALARA experience increased, the value and role of the original guide prompted the DOE Office of Nuclear Safety (ONS) to support a current revision. The revised manual of good practices includes six sections: 1.0 Introduction, 2.0 Administration, 3.0 Optimization, 4.0 Setting and Evaluating ALARA Goals, 5.0 Radiological Design, and 6.0 Conduct of Operations. The manual is directed primarily to contractor and DOE staff who are responsible for conduct and overview of radiation protection and ALARA programs at DOE facilities. The intent is to provide sufficient guidance such that the manual, if followed, will ensure that radiation exposures are maintained as low as reasonably achievable and will establish the basis for a formally structured and auditable program. 118 refs., 16 figs., 3 tabs

  4. Health physics manual of good practices for reducing radiation exposure to levels that are as low as reasonably achievable (ALARA)

    Energy Technology Data Exchange (ETDEWEB)

    Herrington, W.N.; Higby, D.P.; Kathren,., R.L.; Merwin, S.E.; Stoetzel, G.A.

    1988-06-01

    A primary objective of the US Department of Energy (DOE) health physics and radiation protection program has been to limit radiation exposures to those levels that are as low as reasonably achievable (ALARA). As a result, the ALARA concept developed into a program and a set of operational principles to ensure that the objective was consistently met. Implementation of these principles required that a guide be produced. The original ALARA guide was issued by DOE in 1980 to promote improved understanding of ALARA concepts within the DOE community and to assist those responsible for operational ALARA activities in attaining their goals. Since 1980, additional guidance has been published by national and international organizations to provide further definition and clarification to ALARA concepts. As basic ALARA experience increased, the value and role of the original guide prompted the DOE Office of Nuclear Safety (ONS) to support a current revision. The revised manual of good practices includes six sections: 1.0 Introduction, 2.0 Administration, 3.0 Optimization, 4.0 Setting and Evaluating ALARA Goals, 5.0 Radiological Design, and 6.0 Conduct of Operations. The manual is directed primarily to contractor and DOE staff who are responsible for conduct and overview of radiation protection and ALARA programs at DOE facilities. The intent is to provide sufficient guidance such that the manual, if followed, will ensure that radiation exposures are maintained as low as reasonably achievable and will establish the basis for a formally structured and auditable program. 118 refs., 16 figs., 3 tabs.

  5. Occupational and non-occupational allergic contact dermatitis from beryllium.

    Science.gov (United States)

    Vilaplana, J; Romaguera, C; Grimalt, F

    1992-05-01

    There are various references to sensitization to beryllium in the literature. Since introducing a patch testing series for patients with suspected sensitization to metals, we have found 3 cases of sensitization to beryllium. Of these 3 cases, we regard the first 2 as having relevant sensitization. Beryllium chloride (1% pet.) was positive in 3 patients and negative in 150 controls.

  6. 75 FR 80734 - Chronic Beryllium Disease Prevention Program

    Science.gov (United States)

    2010-12-23

    ... Beryllium Disease Prevention Program (CBDPP) (63 FR 66940). After considering the comments received, DOE... CFR Part 850 RIN 1992-AA39 Chronic Beryllium Disease Prevention Program AGENCY: Office of Health... beryllium disease prevention program. The Department solicits comment and information on the...

  7. Spectrographic determination of impurities in beryllium oxide

    International Nuclear Information System (INIS)

    A method for the spectrographic determination of Al, B, Cd, Co, Cu, Cr, Fe, Mg, NaNi, Si and Zn in nuclear grade beryllium oxide has been developed. The determination of Co, Al, Na and Zn is besed upon a carrier distillation technique. Better results were obtained with 2% Ga2O3 as carrier in beryllium oxide. For the elements B, Cd, Cu, Fe, Cr, Mg, Ni and Si the sample is loaded in a Scribner-Mullin shallow cup electrode, covered with graphite powder and excited in DC arc. The relative standard deviation values for different elements are in the range of 10 to 20%. The method fulfills requirements of precision and sensitivity for specification analysis of nuclear grade beryllium oxide.(Author)

  8. Detection of beryllium treatment of natural sapphires by NRA

    Science.gov (United States)

    Gutiérrez, P. C.; Ynsa, M.-D.; Climent-Font, A.; Calligaro, T.

    2010-06-01

    Since the 1990's, artificial treatment of natural sapphires (Al 2O 3 crystals coloured by impurities) by diffusion of beryllium at high temperature has become a growing practice. This process permits to enhance the colour of these gemstones, and thus to increase their value. Detection of such a treatment - diffusion of tens of μg/g of beryllium in Al 2O 3 crystals - is usually achieved using high sensitivity techniques like laser-ablation inductively coupled plasma mass spectrometry (LA-ICP/MS) or laser-induced breakdown spectrometry (LIBS) which are unfortunately micro-destructive (leaving 50-100-μm diameter craters on the gems). The simple and non-destructive alternative method proposed in this work is based on the nuclear reaction 9Be(α, nγ) 12C with an external helium ion beam impinging on the gem directly placed in air. The 4439 keV prompt γ-ray tagging Be atoms are detected with a high efficiency bismuth germanate scintillator. Beam dose is monitored using the 2235 keV prompt γ-ray produced during irradiation by the aluminium of the sapphire matrix through the 27Al(α, pγ) 30Si nuclear reaction. The method is tested on a series of Be-treated sapphires previously analyzed by LA-ICP/MS to determine the optimal conditions to obtain a peak to background appropriate to reach the required μg/g sensitivity. Using a 2.8-MeV external He beam and a beam dose of 200 μC, beryllium concentrations from 5 to 16 μg/g have been measured in the samples, with a detection limit of 1 μg/g.

  9. Detection of beryllium treatment of natural sapphires by NRA

    Energy Technology Data Exchange (ETDEWEB)

    Gutierrez, P.C., E-mail: carolina.gutierrez@uam.e [Centro de Micro-Analisis de Materiales (CMAM), Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid (Spain); Ynsa, M.-D.; Climent-Font, A. [Centro de Micro-Analisis de Materiales (CMAM), Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid (Spain); Dpto. Fisica Aplicada C-12, Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049 Madrid (Spain); Calligaro, T. [Centre de Recherche et de Restauration des musees de France C2RMF, CNRS-UMR171, 14 quai Francois Mitterrand, 75001 Paris (France)

    2010-06-15

    Since the 1990's, artificial treatment of natural sapphires (Al{sub 2}O{sub 3} crystals coloured by impurities) by diffusion of beryllium at high temperature has become a growing practice. This process permits to enhance the colour of these gemstones, and thus to increase their value. Detection of such a treatment - diffusion of tens of {mu}g/g of beryllium in Al{sub 2}O{sub 3} crystals - is usually achieved using high sensitivity techniques like laser-ablation inductively coupled plasma mass spectrometry (LA-ICP/MS) or laser-induced breakdown spectrometry (LIBS) which are unfortunately micro-destructive (leaving 50-100-{mu}m diameter craters on the gems). The simple and non-destructive alternative method proposed in this work is based on the nuclear reaction {sup 9}Be({alpha}, n{gamma}){sup 12}C with an external helium ion beam impinging on the gem directly placed in air. The 4439 keV prompt {gamma}-ray tagging Be atoms are detected with a high efficiency bismuth germanate scintillator. Beam dose is monitored using the 2235 keV prompt {gamma}-ray produced during irradiation by the aluminium of the sapphire matrix through the {sup 27}Al({alpha}, p{gamma}){sup 30}Si nuclear reaction. The method is tested on a series of Be-treated sapphires previously analyzed by LA-ICP/MS to determine the optimal conditions to obtain a peak to background appropriate to reach the required {mu}g/g sensitivity. Using a 2.8-MeV external He beam and a beam dose of 200 {mu}C, beryllium concentrations from 5 to 16 {mu}g/g have been measured in the samples, with a detection limit of 1 {mu}g/g.

  10. [Effects of beryllium chloride on cultured cells].

    Science.gov (United States)

    Sakaguchi, T; Sakaguchi, S; Nakamura, I; Kagami, M

    1984-05-01

    The effects of beryllium on cultured cells were investigated. Three cell-lines (HeLa-S3, Vero, HEL-R66) were used in these experiments and they were cultured in Eagle's MEM plus 5 or 10% FBS (Fetal Bovine Serum) containing beryllium in various concentrations. HeLa cells or Vero cells were able to grow in the medium with 10 micrograms Be/ml (1.1 mM). On the other hand, the growth of HEL cells were strongly inhibited, even when cultured in the medium with 1 microgram Be/ml (1.1 X 10(-1) mM) and the number of living cells showed markedly low level as compared to that of the control samples cultured in the medium without beryllium. The cytotoxic effects of beryllium on these cells, which were cultured for three days in the medium with beryllium, were observed. None of cytotoxic effects were found on HeLa cells cultured with 0.5 micrograms/ml (5.5 X 10(-2) mM) and on Vero cells cultured with 0.05 micrograms Be/ml (5.5 X 10(-3) mM), while HEL cells received cytotoxic effects even when cultured in the medium containing 0.05 micrograms Be/ml (5.5 X 10(-3) mM), and these effects on the cells appeared strong when cultured in the medium without FBS. It was revealed from these experiments that HEL cells are very sensitive in terms of toxic effects of beryllium. Therefore, there cells can be used for the toxicological study on low level concentrations of the metal.

  11. Thawed chilled Barents Sea cod fillets in modified atmosphere packaging-application of multivariate data analysis to select key parameters in good manufacturing practice

    DEFF Research Database (Denmark)

    Bøknæs, Niels; Jensen, K.N.; Guldager, H.S.;

    2002-01-01

    The purpose of the present study was to select key parameters in good manufacturing practice for production of thawed chilled modified atmosphere packed (MAP) cod (Gadus morhua) fillets. The effect of frozen storage temperature (-20 and -30 C), frozen storage period (3, 6, 9 and 12 mo) and chill...... parameters in good manufacturing practice for this product. Frozen storage of up to 12 mo had no significant effect on quality attributes and shelf-life at 2degreesC was above 14 d irrespective of the time of frozen storage. As compared to a previous study with Baltic Sea, cod drip losses during chill...

  12. Health care for immigrants in Europe: is there still consensus among country experts about principles of good practice? A Delphi study

    DEFF Research Database (Denmark)

    Devillé, Walter; Greacen, Tim; Bogic, Marija;

    2011-01-01

    and values of professionals working in different health care contexts and in different European countries as to what constitutes good practice in health care for immigrants. Methods: A total of 134 experts in 16 EU Member States participated in a three-round Delphi process. The experts represented four...... care services for immigrants. Conclusions: Experts across Europe asserted the right to culturally sensitive health care for all immigrants. There is a broad consensus among experts about the major principles of good practice that need to be implemented across Europe. However, there also is some...

  13. Mineral resource of the month: beryllium

    Science.gov (United States)

    Shedd, Kim B.

    2006-01-01

    Beryllium metal is lighter than aluminum and stiffer than steel. These and other properties, including its strength, dimensional stability, thermal properties and reflectivity, make it useful for aerospace and defense applications, such as satellite and space-vehicle structural components. Beryllium’s nuclear properties, combined with its low density, make it useful as a neutron reflector and moderator in nuclear reactors. Because it is transparent to most X rays, beryllium is used as X-ray windows in medical, industrial and analytical equipment.

  14. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing

    DEFF Research Database (Denmark)

    Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent;

    2015-01-01

    INTRODUCTION: Oral anticoagulation treatment (OACT) with warfarin is common in general practice. Increasingly, international normalised ratio (INR) point of care testing (POCT) is being used to manage patients. The aim of this study was to describe and analyse the quality of OACT with warfarin...... in general practice in the Capital Region of Denmark using INR POCT. METHODS: A total of 20 general practices, ten single-handed and ten group practices using INR POCT, were randomly selected to participate in the study. Practice organisation and patient characteristics were recorded. INR measurements were...... collected retrospectively for a period of six months. For each patient, time in therapeutic range (TTR) was calculated and correlated with practice and patient characteristics using multilevel linear regression models. RESULTS: We identified 447 patients in warfarin treatment in the 20 practices using POCT...

  15. Preliminary results for explosion bonding of beryllium to copper

    Energy Technology Data Exchange (ETDEWEB)

    Butler, D.J. [Northwest Technical Industries, Inc., Sequim, WA (United States); Dombrowski, D.E. [Brush Wellman, Inc., Cleveland, OH (United States)

    1995-09-01

    This program was undertaken to determine if explosive bonding is a viable technique for joining beryllium to copper substrates. The effort was a cursory attempt at trying to solve some of the problems associated with explosive bonding beryllium and should not be considered a comprehensive research effort. There are two issues that this program addressed. Can beryllium be explosive bonded to copper substrates and can the bonding take place without shattering the beryllium? Thirteen different explosive bonding iterations were completed using various thicknesses of beryllium that were manufactured with three different techniques.

  16. Bovine cysticercosis in slaughtered cattle as an indicator of Good Agricultural Practices (GAP) and epidemiological risk factors.

    Science.gov (United States)

    Rossi, Gabriel Augusto Marques; Hoppe, Estevam Guilherme Lux; Mathias, Luis Antonio; Martins, Ana Maria Centola Vidal; Mussi, Leila Aparecida; Prata, Luiz Francisco

    2015-03-01

    This study focused on estimating the economic losses resulting from cysticercosis at beef cattle farms that supply an export slaughterhouse located in the state of São Paulo, Brazil, and to identify the epidemiological risks factors involved in the disease to ascertain if these farms adopt Good Agricultural Practices (GAP). To this, we used data recorded in 2012 by Brazil's Federal Inspection Service (SIF) on the daily occurrence of the disease, according to the farm from which the animals originated. In addition, the associated risk factors were determined based on a case-control study at 48 farms. Cysticercosis was detected in 2.26% (95% CI 2.2-2.33) of the 190,903 bovines supplied by 556 farms in the following four states: 2.92% (95% CI 2.83-3.03) in São Paulo, 1.81% (95% CI 1.71-1.93) in Minas Gerais, 0.71% (95% CI 0.6-0.82) in Goiás and 1.11% (95% CI 0.79-1.57) in Mato Grosso do Sul, with significant differences in the epidemiological indices of these states. Cysticercosis was detected at 58.45% (95% CI 54.36-62.55) of the farms of this study, representing estimated economic losses of US$312,194.52 for the farmers. Lower prevalence of this disease were found at the farms qualified for exports to the European Union, indicating a statistically significant difference from those not qualified to export to Europe. The access of cattle to non-controlled water sources, as well as sport fishing activities near the farms, was identified as risk factors. Cysticercosis causes considerable losses in Brazil's beef supply chain, with lower prevalence appearing only at farms qualified to export to the European Union. As for the access of cattle to non-controlled water sources, this is an indication that GAP are not implemented by some farms, demonstrating the violation of international agreements by the industry and the farms. PMID:25631403

  17. Steam chemical reactivity of plasma-sprayed beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Anderl, R.A.; Pawelko, R.J.; Smolik, G.R. [Lockheed Martin Idaho Technologies Co., Idaho Falls, ID (United States). Idaho National Engineering and Environmental Lab.; Castro, R.G. [Los Alamos National Lab., NM (United States)

    1998-07-01

    Plasma-spraying with the potential for in-situ repair makes beryllium a primary candidate for plasma facing and structural components in experimental magnetic fusion machines. Deposits with good thermal conductivity and resistance to thermal cycling have been produced with low pressure plasma-spraying (LPPS). A concern during a potential accident with steam ingress is the amount of hydrogen produced by the reactions of steam with hot components. In this study the authors measure the reaction rates of various deposits produced by LPPS with steam from 350 C to above 1,000 C. They correlate these reaction rates with measurements of density, open porosity and BET surface areas. They find the reactivity to be largely dependent upon effective surface area. Promising results were obtained below 600 C from a 94% theoretical dense (TD) deposit with a BET specific surface area of 0.085 m{sup 2}/g. Although reaction rates were higher than those for dense consolidated beryllium they were substantially lower, i.e., about two orders of magnitude, than those obtained from previously tested lower density plasma-sprayed deposits.

  18. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing

    DEFF Research Database (Denmark)

    Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent;

    2015-01-01

    INTRODUCTION: Oral anticoagulation treatment (OACT)with warfarin is common in general practice. Increasingly,international normalised ratio (INR) point of care testing(POCT) is being used to manage patients. The aim of thisstudy was to describe and analyse the quality of OACT withwarfarin...... in general practice in the Capital Region of Denmarkusing INR POCT. METHODS: A total of 20 general practices, ten singlehandedand ten group practices using INR POCT, were randomlyselected to participate in the study. Practice organisationand patient characteristics were recorded. INRmeasurements were...... was notsignificant (4.2 percentage points (pp); 95% confidenceinterval (CI): –0.8-9.2). Short sampling intervals, e.g. 10-20days (–11 pp, 95% CI: –16-–6)) and lack of diagnostic coding(–11.8 pp; 95% CI: –19.9-–3.7) were correlated with a lowTTR. CONCLUSION: In our study most of the general practices usingINR POCT...

  19. Power and gas suppliers' obligations in their relations with small companies and residential clients (reference system/specifications/good practice code model)

    International Nuclear Information System (INIS)

    This document is a project of good practice manual for the commercial relations between energy suppliers and their clients: prohibition of dishonest practices (fake, aggressive practices, joint sales, lack of information, abuse of vulnerable clients), remote sales and canvassing, pre-contractual information, minimum content of contracts (products and proposed services, tariffs, modalities and conditions of payment, meters, refusal to supply, supply disruption, commitment duration, rescinding, contract renewing, cancellation, contract transfer, modification of contracts in progress, procedure of dispute settlement), minimum content of bills (monthly bill, annual bill); contracts renewing, cancellation, transfer and modification; control and procedure of dispute settlement, disregard of the reference system. (J.S.)

  20. Selecting a Dynamic Simulation Modeling Method for Health Care Delivery Research—Part 2: Report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force

    NARCIS (Netherlands)

    Marshall, Deborah A.; Burgos-Liz, Lina; IJzerman, M.J.; Crown, William; Padula, William V.; Wong, Peter K.; Pasupathy, Kalyan S.; Higashi, Mitchell K.; Osgood, Nathaniel D.

    2015-01-01

    In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling c

  1. Good practice in mental health care for socially marginalised groups in Europe: a qualitative study of expert views in 14 countries

    Directory of Open Access Journals (Sweden)

    Priebe Stefan

    2012-03-01

    Full Text Available Abstract Background Socially marginalised groups tend to have higher rates of mental disorders than the general population and can be difficult to engage in health care. Providing mental health care for these groups represents a particular challenge, and evidence on good practice is required. This study explored the experiences and views of experts in 14 European countries regarding mental health care for six socially marginalised groups: long-term unemployed; street sex workers; homeless; refugees/asylum seekers; irregular migrants and members of the travelling communities. Methods Two highly deprived areas were selected in the capital cities of 14 countries, and experts were interviewed for each of the six marginalised groups. Semi-structured interviews with case vignettes were conducted to explore experiences of good practice and analysed using thematic analysis. Results In a total of 154 interviews, four components of good practice were identified across all six groups: a establishing outreach programmes to identify and engage with individuals with mental disorders; b facilitating access to services that provide different aspects of health care, including mental health care, and thus reducing the need for further referrals; c strengthening the collaboration and co-ordination between different services; and d disseminating information on services both to marginalised groups and to practitioners in the area. Conclusions Experts across Europe hold similar views on what constitutes good practice in mental health care for marginalised groups. Care may be improved through better service organisation, coordination and information.

  2. Access to Gender-Sensitive Higher Education in Eastern and Central Europe: Reflections on the CEPES Project "Good Practice in Promoting Gender Equality in Higher Education"

    Science.gov (United States)

    Grunberg, Laura

    2005-01-01

    Summarizing the incomplete results of the United Nations Educational and Scientific Organization (UNESCO) program "Good Practice in Promoting Gender Equality in Higher Education," the author asks that any assessment of the progress made in the area of gender-sensitive education take regional specificities into account. The regional environment is…

  3. Remarkable Hydrogen Storage on Beryllium Oxide Clusters: First Principles Calculations

    CERN Document Server

    Shinde, Ravindra

    2016-01-01

    Since the current transportation sector is the largest consumer of oil, and subsequently responsible for major air pollutants, it is inevitable to use alternative renewable sources of energies for vehicular applications. The hydrogen energy seems to be a promising candidate. To explore the possibility of achieving a solid-state high-capacity storage of hydrogen for onboard applications, we have performed first principles density functional theoretical calculations of hydrogen storage properties of beryllium oxide clusters (BeO)$_{n}$ (n=2 -- 8). We observed that polar BeO bond is responsible for H$_{2}$ adsorption. The problem of cohesion of beryllium atoms does not arise, as they are an integral part of BeO clusters. The (BeO)$_{n}$ (n=2 -- 8) adsorbs 8--12 H$_{2}$ molecules with an adsorption energy in the desirable range of reversible hydrogen storage. The gravimetric density of H$_{2}$ adsorbed on BeO clusters meets the ultimate 7.5 wt% limit, recommended for onboard practical applications. In conclusion,...

  4. Potential exposures and risks from beryllium-containing products.

    Science.gov (United States)

    Willis, Henry H; Florig, H Keith

    2002-10-01

    Beryllium is the strongest of the lightweight metals. Used primarily in military applications prior to the end of the Cold War, beryllium is finding new applications in many commercial products, including computers, telecommunication equipment, and consumer and automotive electronics. The use of beryllium in nondefense consumer applications is of concern because beryllium is toxic. Inhalation of beryllium dust or vapor causes a chronic lung disease in some individuals at concentrations as low as 0.01 microg/m3 in air. As beryllium enters wider commerce, it is prudent to ask what risks this might present to the general public and to workers downstream of the beryllium materials industry. We address this question by evaluating the potential for beryllium exposure from the manufacturing, use, recycle, and disposal of beryllium-containing products. Combining a market study with a qualitative exposure analysis, we determine which beryllium applications and life cycle phases have the largest exposure potential. Our analysis suggests that use and maintenance of the most common types of beryllium-containing products do not result in any obvious exposures of concern, and that maintenance activities result in greater exposures than product use. Product disposal has potential to present significant individual risks, but uncertainties concerning current and future routes of product disposal make it difficult to be definitive. Overall, additional exposure and dose-response data are needed to evaluate both the health significance of many exposure scenarios, and the adequacy of existing regulations to protect workers and the public. Although public exposures to beryllium and public awareness and concern regarding beryllium risks are currently low, beryllium risks have psychometric qualities that may lead to rapidly heightened public concern. PMID:12442995

  5. Navigating the Good Ol' Boys Club: Women, Marginality, and Communities of Practice in a Military Non-Profit Organization

    Science.gov (United States)

    Callahan, Jamie L.; Tomaszewski, Lesley

    2007-01-01

    When women work in male-dominated organizations, do they form collaborative networks with other women or do they take on the practices of the male-dominated community they are a part of? In this paper, we explore how female staff and volunteer members participate within a male-dominated non-profit organization. We use communities of practice as a…

  6. The utilization of the seven principles for good practices of full-time and adjunct faculty in teaching health & science in community colleges

    Science.gov (United States)

    Musaitif, Linda M.

    Purpose. The purpose of this study was to determine the degree to which undergraduate full-time and adjunct faculty members in the health and science programs at community colleges in Southern California utilize the seven principles of good practice as measured by the Faculty Inventory of the Seven Principles for Good Practice in Undergraduate Education. A second purpose was to compare degree of utilization for gender and class size. Methodology. This is a quantitative study wherein there exists a systematic and mathematical assessment of data gathered through the use of a Likert scale survey to process and determine the mathematical model of the use of the principles by the target population of both full-time and adjunct faculty of health/science programs of community colleges in Southern California. Findings. Examination of the data revealed that both full-time and adjunct faculty members of Southern California community colleges perceive themselves a high degree of utilization of the seven principles of good practice. There was no statistically significant data to suggest a discrepancy between full-time and adjunct professors' perceptions among the utilization of the seven principles. Overall, male faculty members perceived themselves as utilizing the principles to a greater degree than female faculty. Data suggest that faculty with class size 60 or larger showed to utilize the seven principles more frequently than the professors with smaller class sizes. Conclusions. Full-time and adjunct professors of the health and sciences in Southern California community colleges perceive themselves as utilizing the seven principles of good practice to a high degree. Recommendations. This study suggests many recommendations for future research, including the degree to which negative economic factors such as budget cuts and demands affect the utilization of the seven principles. Also recommended is a study comparing students' perceptions of faculty's utilization of the seven

  7. A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice

    Directory of Open Access Journals (Sweden)

    Gola Mauro

    2009-09-01

    Full Text Available Abstract Background Main scope of the EU and FDA regulations is to establish a classification criterion for advanced therapy medicinal products (ATMP. Regulations require that ATMPs must be prepared under good manufacturing practice (GMP. We have validated a commercial system for the determination of bacterial endotoxins in compliance with EU Pharmacopoeia 2.6.14, the sterility testing in compliance with EU Pharmacopoeia 2.6.1 and a potency assay in an ATMP constituted of mononucleated cells used in cardiac regeneration. Methods For the potency assay, cells were placed in the upper part of a modified Boyden chamber containing Endocult Basal Medium with supplements and transmigrated cells were scored. The invasion index was expressed as the ratio between the numbers of invading cells relative to cell migration through a control insert membrane. For endotoxins, we used a commercially available system based on the kinetic chromogenic LAL-test. Validation of sterility was performed by direct inoculation of TSB and FTM media with the cell product following Eu Ph 2.6.1 guideline. Results and discussion The calculated MVD and endotoxin limit were 780× and 39 EU/ml respectively. The 1:10 and 1:100 dilutions were selected for the validation. For sterility, all the FTM cultures were positive after 3 days. For TSB cultures, Mycetes and B. subtilis were positive after 5 and 3 days respectively. The detection limit was 1-10 colonies. A total of four invasion assay were performed: the calculated invasion index was 28.89 ± 16.82% (mean ± SD. Conclusion We have validated a strategy for endotoxin, sterility and potency testing in an ATMP used in cardiac regeneration. Unlike pharmaceutical products, many stem-cell-based products may originate in hospitals where personnel are unfamiliar with the applicable regulations. As new ATMPs are developed, the regulatory framework is likely to evolve. Meanwhile, existing regulations provide an appropriate structure for

  8. Medical and Dental Guidance Notes. A Good Practice Guide on all Aspects of Ionising Radiation Protection in the Clinical Environment

    International Nuclear Information System (INIS)

    Institute of Physics and Engineering in Medicine York: IPEM 225 pp, ISBN: 1-903613-09-4. This book is the much awaited replacement for the old yellow 'Guidance Notes' published in 1988 by the National Radiological Protection Board (NRPB). Since then nearly all Regulations covering the use of ionising radiation have been updated. The Institute of Physics and Engineering in Medicine (IPEM) established a working group in 1999 to produce a first draft for consultation (produced in April 2000) and to consider subsequent comments to this draft. The final document, published by IPEM, is therefore the end product of numerous contributions from professionals working in healthcare and wide consultation with professional bodies, the NRPB, UK Health Departments, Environment Agencies and the HSE. The notes provide general guidance on good practice - not just legal requirements. Radiation Protection Advisers and Medical Physics Experts may well have instigated slightly different arrangements locally. The publication has been available in electronic form on the IPEM website ( www.ipem.org.uk/publications/IRR99.html) for a few months. This has been useful for quick access to advice and for searching for particular topics but is difficult to read in large sections. Although it can be downloaded, the main documented is protected so that it can not be printed and specific text can not be 'cut and pasted'. The appendices are in a separate file that can be printed. Although the chapter paragraph numbers are consistent between the electronic and papers versions, the page numbers are different. The new guidance is ring bound, so, apart from at the beginning and end of the book, it is generally easy to open it out and lay it flat. The book consists of 19 chapters and 21 appendices and, with 225 pages, is considerably more extensive than the old notes. It begins with the general measures for radiation protection followed by radiation protection of persons undergoing medical exposures

  9. Patterns and processes of nutrient transfers from land to water: a catchment approach to evaluate Good Agricultural Practice in Ireland

    Science.gov (United States)

    Mellander, P.-E.; Melland, A. R.; Shortle, G.; Wall, D.; Mechan, S.; Buckley, C.; Fealy, R.; Jordan, P.

    2009-04-01

    Eutrophication of fresh, transitional and coastal waters by excessive nutrient inputs is one of the most widespread water quality problems in developed countries. Sources of nutrient nitrogen (N) and phosphorus (P) can come from a multiplicity of sources and be dependent on numerous hydrological controls from catchments with both urban and agricultural landuses. Aquatic impacts are widely reported as a result of excessive nutrient transfers from land to water and include changes in ecological integrity and loss of amenity. In the European Union, the Water Framework Directive (WFD) and associated Directives are the key structures with which member states must develop national and often trans-national polices to deal with issues of water resources management. The linked Nitrates Directive is particularly concerned with integrating sustainable agriculture and good water quality objectives and is written into national polices. In Ireland this policy is the Nitrates Directive National Action Programme (NAP), Statutory Instruction 378, Good Agricultural Practise regulation, and amongst other things, sets targets and limits on the use of organic and inorganic fertilisers, soil fertility and slurry/fertiliser spreading and cultivation times. To evaluate the effectiveness of this policy, Teagasc, the Irish Agriculture and Food Development Authority, is undertaking a catchment scale audit on sources, sinks, and changes in nutrient use and export over several years. The Agricultural Catchments Programme is based on a science-stakeholder-management partnership to generate knowledge and specifically to protect water quality from nitrogen and phosphorus transfers within the constraints of the requirements of modern Irish agricultural practises. Eight catchments of 5-12 km2 have been selected for the programme to represent a range of agricultural intensities and vulnerabilities to nitrogen and phosphorus loss including catchments that are situated on permeable and impermeable

  10. A NEAR REAL-TIME BERYLLIUM MONITOR WITH CAM AND WIPE ANALYSIS CAPABILITIES

    Energy Technology Data Exchange (ETDEWEB)

    D.T. Kendrick; Steven Saggese

    2002-12-01

    element in the sample. The monitor can be operated in one of two modes, as a continuous air monitor (CAM), or as a wipe monitor. In its CAM mode, the monitor collects an air sample for a user programmable sampling time on a conventional mixed cellulose ester (MCE) filter. The monitor can also be used in a wipe analysis mode, where the user can load up to 60 previously collected wipe samples, typically obtained on 47 mm filter media, into disposable filter cassettes. Under this effort, a beryllium monitor was designed, fabricated and tested. During laboratory testing, the monitor's measurement performance met the stated measurement objectives at the outset of the project. A typical minimum detectable beryllium mass for the monitor is below the 0.2 mg/m{sup 3} goal of the project. Field-testing of the monitor show it to exhibit extremely good sensitivity to very low levels of beryllium. On a per spark basis, the monitor has been shown to be capable of detecting a few tens of picograms of beryllium. At the culmination of the project, the beryllium CAM unit was delivered to the U.S. DOE-Rocky Flats Environmental Management Site where it is undergoing additional on-site evaluations.

  11. Safety handling of beryllium for fusion technology R and D

    International Nuclear Information System (INIS)

    Feasibility of beryllium use as a blanket neutron multiplier, first wall and plasma facing material has been studied for the D-T burning experiment reactors such as ITER. Various experimental work of beryllium and its compounds will be performed under the conditions of high temperature and high energy particle exposure simulating fusion reactor conditions. Beryllium is known as a hazardous substance and its handling has been carefully controlled by various health and safe guidances and/or regulations in many countries. Japanese regulations for hazardous substance provide various guidelines on beryllium for the protection of industrial workers and environment. This report was prepared for the safe handling of beryllium in a laboratory scale experiments for fusion technology R and D such as blanket development. Major items in this report are; (1) Brief review of guidances and regulations in USA, UK and Japan. (2) Safe handling and administration manuals at beryllium facilities in INEL, LANL and JET. (3) Conceptual design study of beryllium handling facility for small to mid-scale blanket R and D. (4) Data on beryllium toxicity, example of clinical diagnosis of beryllium disease, and environmental occurence of beryllium. (5) Personnel protection tools of Japanese Industrial Standard for hazardous substance. (author) 61 refs

  12. Control of beryllium powder at a DOE facility

    International Nuclear Information System (INIS)

    Beryllium is contained in a number of domestic and national defense items. Although many items might contain beryllium in some manner, few people need worry about the adverse effects caused by exposure to beryllium because it is the inhalable form of beryllium that is most toxic. Chronic beryllium disease (CBD), a granulomas and fibrotic lung disease with long latency, can be developed after inhalation exposures to beryllium. It is a progressive, debilitating lung disease. Its occurrence in those exposed to beryllium has been difficult to predict because some people seem to react to low concentration exposures whereas others do not react to high concentration exposures. Onset of the disease frequently occurs between 15 to 20 years after exposure begins. Some people develop the disease after many years of low concentration exposures but others do not develop CBD even though beryllium is shown to be present in lungs and urine. Conclusions based on these experiences are that their is some immunological dependence of developing CBD in about 3--4% of the exposed population, but the exact mechanism involved has not yet been identified. Acute beryllium disease can occur after a single exposure to a concentration of greater than 0.100 mg/m3 (inhalation exposure); it is characterized by the development of chemical pneumoconiosis, a respiratory disease. The acute effect of skin contact is a dermatitis characterized by itching and reddened, elevated, or fluid-accumulated lesions which appear particularly on the exposed surfaces of the body, especially the face, neck, arms, and hands. Small particles of beryllium that enter breaks in the skin can lead to the development of granulomas and/or open sores that do not heal until the beryllium has been removed. Our interest is only airborne beryllium, which is found in areas that machine or produce beryllium

  13. Good Relations between Foster Parents and Birth Parents: A Swedish Study of Practices Promoting Successful Cooperation in Everyday Life

    Science.gov (United States)

    Hedin, Lena

    2015-01-01

    The importance for foster children's well-being of good relations between foster parents and birth parents is a common topic of research. This article aims to contribute to an understanding of how co-parenting by foster parents and birth parents works in everyday life, from both parties' perspectives, whether or not they knew each other…

  14. Practice Paper of the Academy of Nutrition and Dietetics: Selecting Nutrient-Dense Foods for Good Health.

    Science.gov (United States)

    Hingle, Melanie D; Kandiah, Jayanthi; Maggi, Annette

    2016-09-01

    The 2015 Dietary Guidelines for Americans encourage selection of nutrient-dense foods for health promotion and disease prevention and management. The purpose of this Academy of Nutrition and Dietetics practice paper is to provide an update regarding the science and practice of nutrient-dense food identification and selection. Characterization of tools used to identify nutrient density of foods is provided and recommendations for how registered dietitian nutritionists and nutrition and dietetics technicians, registered, might use available profiling tools to help consumers select nutrient-dense foods is discussed. PMID:27568089

  15. Forward Commitment Procurement : A practical methodology that helps to manage risk in procuring innovative goods and services

    NARCIS (Netherlands)

    Whyles, G.; Meerveld, H. van; Nauta, N.J.

    2015-01-01

    The Forward Commitment Procurement (FCP) is a Public Procurement of Innovation (PPI) methodology. It was specifically designed to both provide a practical methodology for procurers to follow and to manage the perceived risk of the customer and supplier in innovation investments. The paper describes

  16. Vocabulary Intervention for School-Age Children with Language Impairment: A Review of Evidence and Good Practice

    Science.gov (United States)

    Steele, Sara C.; Mills, Monique T.

    2011-01-01

    The purpose of this article is to provide evidence to support direct vocabulary intervention practices for primary school-age children with language impairment (LI). A rationale for providing direct vocabulary intervention for children with LI is outlined by reviewing typical and atypical vocabulary acquisition, evidence of instructional…

  17. "I Am Trying to Practice Good Teaching": Reconceptualizing ePortfolios for Professional Development in Vocational Higher Education

    Science.gov (United States)

    Winberg, Christine; Pallitt, Nicola

    2016-01-01

    Teaching portfolios have become increasingly important to university teachers. Portfolio requirements for the appointment or promotion of academic staff recognize that the assessment of teaching practice requires more depth and detail than a candidate's academic CV generally affords. The focus of this study is the electronic teaching portfolios,…

  18. Practice Prize Article—: A Multichannel, Multiregion Sales Forecasting Model and Decision Support System for Consumer Packaged Goods

    OpenAIRE

    Suresh Divakar; Ratchford, Brian T; Venkatesh Shankar

    2005-01-01

    We discuss the development and implementation of , a sales forecasting model, by pack size, category, channel, region, customer account and a Web-based decision support system (DSS) for consumer packaged goods. In addition to capturing the effects of such variables as past sales, trend, own and competitor prices and promotional variables, and seasonality, the model accounts for the effects of temperature, significant holidays, new product introductions, trading day corrections, and adjustment...

  19. Aid conditionalities, international Good Manufacturing Practice standards and local production rights:A case study of local production in Nepal

    OpenAIRE

    Brhlikova, Petra; Harper, Ian; Subedi, Madhusudan; Bhattarai, Samita; Rawal, Nabin; Pollock, Allyson M.

    2015-01-01

    Background: Local pharmaceutical production has been endorsed by the WHO as a means of addressing health priorities of developing countries. However, local producers of essential medicines must comply with international pharmaceutical standards in order to be eligible to compete in donor tenders. These standards determine production rights for on-patent and off-patent medicines, and guide international procurement of medicines. We reviewed the literature on the impact of Good Manufacturing Pr...

  20. Social Good and Stakeholders' Engagement in the Pharmaceutical Industry : Case Study of AstraZeneca Corporate Responsibility Practices

    OpenAIRE

    Rusinowska, Magdalena; Traverso, Victoria

    2009-01-01

    Private organizations are facing organizational field pressures which need to be addressed from an economic and ethical point of view in order to be sustainable in the long term. The present research study analyzes the role of the Pharmaceutical Industry as a provider of a social good and its responsibility towards its organizational field and stakeholder network. On the one hand it is argued that the mentioned industry should be profitable in order to make investments in research and develop...

  1. Study on neutron irradiation behavior of beryllium as neutron multiplier

    Energy Technology Data Exchange (ETDEWEB)

    Ishitsuka, Etsuo [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

    1998-03-01

    More than 300 tons beryllium is expected to be used as a neutron multiplier in ITER, and study on the neutron irradiation behavior of beryllium as the neutron multiplier with Japan Materials Testing Reactor (JMTR) were performed to get the engineering data for fusion blanket design. This study started as the study on the tritium behavior in beryllium neutron reflector in order to make clear the generation mechanism on tritium of JMTR primary coolant since 1985. These experiences were handed over to beryllium studies for fusion study, and overall studies such as production technology of beryllium pebbles, irradiation behavior evaluation and reprocessing technology have been started since 1990. In this presentation, study on the neutron irradiation behavior of beryllium as the neutron multiplier with JMTR was reviewed from the point of tritium release, thermal properties, mechanical properties and reprocessing technology. (author)

  2. Status of material development for lifetime expansion of beryllium reflector

    International Nuclear Information System (INIS)

    Beryllium has been used as the reflector element material in the reactor, specifically S-200F structural grade beryllium manufactured by Materion Brush Beryllium and Composites (former, Brush Wellman Inc.). As a part of the reactor upgrade, the Japan Atomic Energy Agency (JAEA) also has carried out the cooperation experiments to extend the operating lifetime of the beryllium reflector elements. It will first be necessary to determine which of the material's physical, mechanical and chemical properties will be the most influential on that choice. The irradiation testing plans to evaluate the various beryllium grades are also briefly considered and prepared. In this paper, material selection, irradiation test plan and PEI development for lifetime expansion of beryllium are described for material testing reactors. (author)

  3. Mechanisms of hydrogen retention in metallic beryllium and beryllium oxide and properties of ion-induced beryllium nitride; Rueckhaltemechanismen fuer Wasserstoff in metallischem Beryllium und Berylliumoxid sowie Eigenschaften von ioneninduziertem Berylliumnitrid

    Energy Technology Data Exchange (ETDEWEB)

    Oberkofler, Martin

    2011-09-22

    In the framework of this thesis laboratory experiments on atomically clean beryllium surfaces were performed. They aim at a basic understanding of the mechanisms occurring upon interaction of a fusion plasma with a beryllium first wall. The retention and the temperature dependent release of implanted deuterium ions are investigated. An atomistic description is developed through simulations and through the comparison with calculations based on density functional theory. The results of these investigations are compared to the behaviour of hydrogen upon implantation into thermally grown beryllium oxide layers. Furthermore, beryllium nitride is produced by implantation of nitrogen into metallic beryllium and its properties are investigated. The results are interpreted with regard to the use of beryllium in a fusion reactor. (orig.)

  4. Characterization of plasma sprayed beryllium ITER first wall mockups

    Energy Technology Data Exchange (ETDEWEB)

    Castro, R.G.; Vaidya, R.U.; Hollis, K.J. [Los Alamos National Lab., NM (United States). Material Science and Technology Div.

    1998-01-01

    ITER first wall beryllium mockups, which were fabricated by vacuum plasma spraying the beryllium armor, have survived 3000 thermal fatigue cycles at 1 MW/m{sup 2} without damage during high heat flux testing at the Plasma Materials Test Facility at Sandia National Laboratory in New Mexico. The thermal and mechanical properties of the plasma sprayed beryllium armor have been characterized. Results are reported on the chemical composition of the beryllium armor in the as-deposited condition, the through thickness and normal to the through thickness thermal conductivity and thermal expansion, the four-point bend flexure strength and edge-notch fracture toughness of the beryllium armor, the bond strength between the beryllium armor and the underlying heat sink material, and ultrasonic C-scans of the Be/heat sink interface. (author)

  5. 良好农业规范在烟草种植中的应用%Application of Good Agricultural Practices in Tobacco Cultivation

    Institute of Scientific and Technical Information of China (English)

    邵晓丽; 杨明; 张如阳; 王学坚; 许文

    2011-01-01

    Good agricultural practices are generally considered as a good agricultural management system.Taking Pu′er tobacco area for example,the GAP implementation of specific practices in tobacco cultivation were described in detail,to improve the management stan%良好农业规范是国际普遍认可的应用于农业生产领域的一套管理体系。以云南省普洱市烟区为例,详细介绍了在烟草种植中推行GAP的具体做法,以期提升我国烟草种植管理水平和烟叶品质及安全性。

  6. Italy; Financial Sector Assessment Program: Detailed Assessment of Observance of the IMF Code of Good Practices on Transparency in Monetary and Financial Policies: Payment Systems Oversight

    OpenAIRE

    International Monetary Fund

    2006-01-01

    This paper discusses a Detailed Assessment of the Observance of the IMF Code of Good Practices on Transparency in Monetary and Financial Policies for Payment Systems Oversight for Italy. The Banca d’Italia’s (BI) oversight of payment systems is characterized by high levels of transparency, benefiting from clarity in the European Union-wide institutional framework, and actively contributing to its timely disclosure of policy developments and exchange of information. The BI routinely disclo...

  7. Debating the Implications of the Urban Councils Act Chapter 29.15 (1996) On the Practice of Good Corporate Governance in Zimbabwe‘s Urban Local Authorities

    OpenAIRE

    Edson Paul Mutema

    2012-01-01

    This paper debates the implications of the Urban Councils Act (UCA) on the practice of good corporate governance in Zimbabwean urban local authorities. The study revealed that the act upholds corporate governance in urban councils through providing for: council meetings that are open to the public and the press, council minutes which are available for public inspection and a municipal procurement board that manages the tender system of urban councils just to mention a few. However the study a...

  8. Eco-innovation and management in time of crisis: a comparative analysis of environmental good practices and labour productivity in the spanish hotel industry (2008-2012)

    OpenAIRE

    Sánchez Ollero, José Luis; García Pozo, Alejandro; Pérez González, María del Carmen

    2014-01-01

    The economic crisis in recent years has significantly affected the Spanish hospitality industry. Some factors that affect labor productivity and therefore business performance in this sector may have affected the productivity in a different way when the economic crisis in Spain became deeper. One such factor is the eco-innovation. In previous works, the authors of this paper have used a variable that holds a set of good environmental practices to analyze the impact of the introduction of eco...

  9. Plasma cleaning of beryllium coated mirrors

    Science.gov (United States)

    Moser, L.; Marot, L.; Steiner, R.; Newman, M.; Widdowson, A.; Ivanova, D.; Likonen, J.; Petersson, P.; Pintsuk, G.; Rubel, M.; Meyer, E.; Contributors, JET

    2016-02-01

    Cleaning systems of metallic first mirrors are needed in more than 20 optical diagnostic systems from ITER to avoid reflectivity losses. Currently, plasma sputtering is considered as one of the most promising techniques to remove deposits coming from the main wall (mainly beryllium and tungsten). This work presents the results of plasma cleaning of rhodium and molybdenum mirrors exposed in JET-ILW and contaminated with typical tokamak elements (including beryllium and tungsten). Using radio frequency (13.56 MHz) argon or helium plasma, the removal of mixed layers was demonstrated and mirror reflectivity improved towards initial values. The cleaning was evaluated by performing reflectivity measurements, scanning electron microscopy, x-ray photoelectron spectroscopy and ion beam analysis.

  10. Ion-plasma deposition of aluminium and beryllium coatings on inner surfaces of hollow cylindrical cathodes

    International Nuclear Information System (INIS)

    Application of metal coatings to inner surfaces of hollow cylindrical products of small diameter is simulated and practically realized by ion-plasma deposition method. In the modes proposed and with the cylinder diameter being 10-20 mm, a uniform coating of aluminium and beryllium is provided for at the length equal to (3-4) d, which has not been possible to be realized previously. 11 refs.; 2 tabs

  11. Cost-effective facility disposition planning with safety and health lessons learned and good practices from the Oak Ridge Decontamination and Decommissioning Program

    International Nuclear Information System (INIS)

    An emphasis on transition and safe disposition of DOE excess facilities has brought about significant challenges to managing worker, public, and environmental risks. The transition and disposition activities involve a diverse range of hazardous facilities that are old, poorly maintained, and contain radioactive and hazardous substances, the extent of which may be unknown. In addition, many excess facilities do not have historical facility documents such as operating records, plant and instrumentation diagrams, and incident records. The purpose of this report is to present an overview of the Oak Ridge Decontamination and Decommissioning (D and D) Program, its safety performance, and associated safety and health lessons learned and good practices. Illustrative examples of these lessons learned and good practices are also provided. The primary focus of this report is on the safety and health activities and implications associated with the planning phase of Oak Ridge facility disposition projects. Section 1.0 of this report provides the background and purpose of the report. Section 2.0 presents an overview of the facility disposition activities from which the lessons learned and good practices discussed in Section 3.0 were derived

  12. Neutron counter based on beryllium activation

    Energy Technology Data Exchange (ETDEWEB)

    Bienkowska, B.; Prokopowicz, R.; Kaczmarczyk, J.; Paducha, M. [Institute of Plasma Physics and Laser Microfusion (IPPLM), Hery 23, 01-497 Warsaw (Poland); Scholz, M.; Igielski, A. [Institute of Nuclear Physics PAS (IFJPAN), Radzikowskiego 152, 31-342 Krakow (Poland); Karpinski, L. [Faculty of Electrical Engineering, Rzeszow University of Technology, Pola 2, 35-959 Rzeszow (Poland); Pytel, K. [National Centre for Nuclear Research (NCBJ), Soltana 7, 05-400 Otwock - Swierk (Poland)

    2014-08-21

    The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction {sup 9}Be(n, α){sup 6}He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, {sup 6}He, decays with half-life T{sub 1/2} = 0.807 s emitting β{sup −} particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of β–particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known β–source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5–the Monte Carlo transport code. It allowed proper application of the results of transport calculations of β{sup −} particles emitted from radioactive {sup 6}He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

  13. Neutron counter based on beryllium activation

    Science.gov (United States)

    Bienkowska, B.; Prokopowicz, R.; Scholz, M.; Kaczmarczyk, J.; Igielski, A.; Karpinski, L.; Paducha, M.; Pytel, K.

    2014-08-01

    The fusion reaction occurring in DD plasma is followed by emission of 2.45 MeV neutrons, which carry out information about fusion reaction rate and plasma parameters and properties as well. Neutron activation of beryllium has been chosen for detection of DD fusion neutrons. The cross-section for reaction 9Be(n, α)6He has a useful threshold near 1 MeV, which means that undesirable multiple-scattered neutrons do not undergo that reaction and therefore are not recorded. The product of the reaction, 6He, decays with half-life T1/2 = 0.807 s emitting β- particles which are easy to detect. Large area gas sealed proportional detector has been chosen as a counter of β-particles leaving activated beryllium plate. The plate with optimized dimensions adjoins the proportional counter entrance window. Such set-up is also equipped with appropriate electronic components and forms beryllium neutron activation counter. The neutron flux density on beryllium plate can be determined from the number of counts. The proper calibration procedure needs to be performed, therefore, to establish such relation. The measurements with the use of known β-source have been done. In order to determine the detector response function such experiment have been modeled by means of MCNP5-the Monte Carlo transport code. It allowed proper application of the results of transport calculations of β- particles emitted from radioactive 6He and reaching proportional detector active volume. In order to test the counter system and measuring procedure a number of experiments have been performed on PF devices. The experimental conditions have been simulated by means of MCNP5. The correctness of simulation outcome have been proved by measurements with known radioactive neutron source. The results of the DD fusion neutron measurements have been compared with other neutron diagnostics.

  14. What Confucius practiced is good for your mind: Examining the effect of a contemplative practice in Confucian tradition on executive functions.

    Science.gov (United States)

    Teng, Shan-Chuan; Lien, Yunn-Wen

    2016-05-01

    The short-term training effects on various executive functions (EFs) by a movement-based contemplative practice (MBCP) are examined. Three aspects of EFs (working memory capacity, inhibition, switching) are assessed before and after a month-long 12-h training period using Body-Mind Axial Awareness (BMAA) principles that Confucius followers have practiced for more than 2000years. A mindfulness-based practice (Chan-meditation) and a waiting-list control group served as contrast groups. Our results showed that the BMAA group performed better on the task that measured working memory capacity than did the Chan-meditation and the waiting-list groups after training. In addition, the Chan-meditation groups outperformed the control group on attentional switching, a novel finding for this kind of practice. Our findings not only show a new effect of short-term MBCPs on EFs, but also indicate movement-based and mindfulness-based contemplative practices might benefit development of various aspects of EFs in different ways.

  15. Using spirometry results in occupational medicine and research: Common errors and good practice in statistical analysis and reporting

    OpenAIRE

    Wagner N; Beckett W; Steinberg R

    2006-01-01

    Spirometry appears to be a simple and inexpensive method to measure disorders of the respiratory tract. In reality however, a simple spirometry test requires knowledge and skill to correctly conduct and evaluate the test and its results. This review addresses common misunderstandings in using, evaluating and reporting spirometry results in Occupational Health practice, clinical medicine and research. Results of spirometry need to be evaluated in relation to reference values. The factory medic...

  16. The Ideas of God, Good and Evil in the Refigured Yoga Practices in Metropolitan area of Buenos Aires city

    OpenAIRE

    Mercedes Saizar

    2011-01-01

    Yoga is a widespread therapeutic option; it is the most popular among the oriental rooted medicines, what is more, is accepted and recommended by biomedical doctors like a complementary medicine. Currently, in a context of alternatives therapies offer, yoga appears like one of the disciplines which certain individual uses at least once in their ways of health search. The variety of options, cost and modality of the practice, the appropriation and acceptance on part of dissimilar groups, the p...

  17. [French Society of Vascular Medicine good medical practice guidelines on safety and environment in vascular medicine: Treatment of varicose veins].

    Science.gov (United States)

    Giordana, P; Miserey, G

    2014-12-01

    These guidelines proposed by the French Society of Vascular Medicine define the optimal environment for vascular medicine practice: outpatient clinic; equipment, layout and maintenance of the care center; infection risk prevention (hand hygiene, individual protective measures, exposure to blood, ultrasound apparatus, etc.); common interventions and techniques (liquid and foam sclerotherapy, endovenous thermal treatments). These guidelines do not include phlebectomy and use of ultrasound contrast agents.

  18. ORGANIZATIONAL GOOD PRACTICES FOR THE INTEGRATION OF THE ICT IN THE EDUCATION SYSTEM OF EXTREMADURA BUENAS PRÁCTICAS ORGANIZATIVAS PARA LA INTEGRACIÓN DE LAS TIC EN EL SISTEMA EDUCATIVO EXTREMEÑO

    OpenAIRE

    Mª José Sosa Díaz; Sara Peligros García; Dionisio Díaz Muriel

    2010-01-01

    The present paper tries to release some organizational Good Practices for the integration of the ICT's carried out by the Education System in Extremadura. For this, in a first moment, a theoretical review about the concept of Good Practices has been done, establishing some indicators which permit us identify Good Practices regarding the application of the ICT within Primary and Secondary schools, and specially pointing out the indicators that refer to organizational aspects in the education...

  19. Behavior of beryllium pebbles under irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Dalle-Donne, M.; Scaffidi-Argentina, F. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reactortechnik; Baldwin, D.L.; Gelles, D.S.; Greenwood, L.R.; Kawamura, H.; Oliver, B.M.

    1998-01-01

    Beryllium pebbles are being considered in fusion reactor blanket designs as neutron multiplier. An example is the European `Helium Cooled Pebble Bed Blanket.` Several forms of beryllium pebbles are commercially available but little is known about these forms in response to fast neutron irradiation. Commercially available beryllium pebbles have been irradiated to approximately 1.3 x 10{sup 22} n/cm{sup 2} (E>1 MeV) at 390degC. Pebbles 1-mm in diameter manufactured by Brush Wellman, USA and by Nippon Gaishi Company, Japan, and 3-mm pebbles manufactured by Brush Wellman were included. All were irradiated in the below-core area of the Experimental Breeder Reactor-II in Idaho Falls, USA, in molybdenum alloy capsules containing helium. Post-irradiation results are presented on density change measurements, tritium release by assay, stepped-temperature anneal, and thermal ramp desorption tests, and helium release by assay and stepped-temperature anneal measurements, for Be pebbles from two manufacturing methods, and with two specimen diameters. The experimental results on density change and tritium and helium release are compared with the predictions of the code ANFIBE. (author)

  20. Interaction of nitrogen ions with beryllium surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Dobes, Katharina [Institute of Applied Physics, TU Wien, Association EURATOM ÖAW, Vienna (Austria); Köppen, Martin [Institute of Energy and Climate Research – Plasma Physics, Forschungszentrum Jülich GmbH, 52425 Jülich (Germany); Oberkofler, Martin [Max-Planck-Institut für Plasmaphysik, Boltzmannstraße 2, D-85748 Garching (Germany); Lungu, Cristian P.; Porosnicu, Corneliu [National Institute for Laser, Plasma, and Radiation Physics, Bucharest (Romania); Höschen, Till; Meisl, Gerd [Max-Planck-Institut für Plasmaphysik, Boltzmannstraße 2, D-85748 Garching (Germany); Linsmeier, Christian [Institute of Energy and Climate Research – Plasma Physics, Forschungszentrum Jülich GmbH, 52425 Jülich (Germany); Aumayr, Friedrich, E-mail: aumayr@iap.tuwien.ac.at [Institute of Applied Physics, TU Wien, Association EURATOM ÖAW, Vienna (Austria)

    2014-12-01

    The interaction of energetic nitrogen projectiles with a beryllium surface is studied using a highly sensitive quartz crystal microbalance technique. The overall mass change rate of the beryllium sample under N{sub 2}{sup +} ion impact at an ion energy of 5000 eV (i.e. 2500 eV per N) is investigated in situ and in real-time. A strong dependency of the observed mass change rate on the nitrogen fluence (at constant flux) is found and can be attributed to the formation of a nitrogen-containing mixed material layer within the ion penetration depth. The presented data elucidate the dynamics of the interaction process and the surface saturation with increasing nitrogen fluence in a unique way. Basically, distinct interaction regimes can be discriminated, which can be linked to the evolution of the surface composition upon nitrogen impact. Steady state surface conditions are obtained at a total cumulative nitrogen fluence of ∼80 × 10{sup 16} N atoms per cm{sup 2}. In dynamic equilibrium, the interaction is marked by continuous surface erosion. In this case, the observed total sputtering yield becomes independent from the applied nitrogen fluence and is of the order of 0.4 beryllium atoms per impinging nitrogen atom.

  1. Beryllium-10 in Australasian tektites - Evidence for a sedimentary precursor

    Science.gov (United States)

    Pal, D. K.; Moniot, R. K.; Kruse, T. H.; Herzog, G. F.; Tuniz, C.

    1982-01-01

    Each of seven Australasian tektites contains about 100 micron atoms of beryllium-10 (half-life, 1.53 million years) per gram. Cosmic-ray bombardment of the australites cannot have produced the measured amounts of beryllium-10 either at the earth's surface or in space. The beryllium-10 contents of these australites are consistent with a sedimentary precursor that adsorbed from precipitation beryllium-10 produced in the atmosphere. The sediments must have spent several thousand years at the earth's surface within a few million years of the tektite-producing event.

  2. Vocabulary Intervention for School-age Children with Language Impairment: A Review of Evidence and Good Practice.

    Science.gov (United States)

    Steele, Sara C; Mills, Monique T

    2011-11-01

    The purpose of this paper is to provide evidence to support direct vocabulary intervention practices for primary school-age children with language impairment (LI). A rationale for providing direct vocabulary intervention for children with LI is outlined by reviewing typical and atypical vocabulary acquisition, evidence of instructional strategies from research in mainstream and special education is summarised, and suggestions for vocabulary intervention activities that facilitate deep word knowledge are provided. Suggestions for choosing appropriate vocabulary, using strategies during direct intervention, and conducting activities that increase depth of vocabulary knowledge are included.

  3. The Effect of Social perception of environmental problems and goods on the practice of cost-benefit analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bunuel, M.; Delgado, M. L.

    2002-07-01

    When revealed, willingness to pay (WTP) is considerably lesser than willingness to accept (WTA), as economists explain. Sociological studies in Spain reveal that citizens assign a high value to the environment (high WTA), but are not ready to pay to preserve it (low WTP)because they think that it is industrial sector and the government's responsibility. This is a new factor, not studied before, that may result in underestimating environmental goods when WTP is used. The gap between WTP and WTA makes cost-benefits analysis difficult, creating the risk of environmental political judgments being replaced by pseudo scientific noise instead of by objective economic analysis.hence, it is sometimes convenient to use alternative methods to cost-benefit analysis: cost-effectiveness analysis trade-off analysis, economic-impact valuation, and risk-benefit analysis. (Author)

  4. State-transition modeling: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force--3.

    Science.gov (United States)

    Siebert, Uwe; Alagoz, Oguzhan; Bayoumi, Ahmed M; Jahn, Beate; Owens, Douglas K; Cohen, David J; Kuntz, Karen M

    2012-01-01

    State-transition modeling is an intuitive, flexible, and transparent approach of computer-based decision-analytic modeling including both Markov model cohort simulation and individual-based (first-order Monte Carlo) microsimulation. Conceptualizing a decision problem in terms of a set of (health) states and transitions among these states, state-transition modeling is one of the most widespread modeling techniques in clinical decision analysis, health technology assessment, and health-economic evaluation. State-transition models have been used in many different populations and diseases, and their applications range from personalized health care strategies to public health programs. Most frequently, state-transition models are used in the evaluation of risk factor interventions, screening, diagnostic procedures, treatment strategies, and disease management programs. The goal of this article was to provide consensus-based guidelines for the application of state-transition models in the context of health care. We structured the best practice recommendations in the following sections: choice of model type (cohort vs. individual-level model), model structure, model parameters, analysis, reporting, and communication. In each of these sections, we give a brief description, address the issues that are of particular relevance to the application of state-transition models, give specific examples from the literature, and provide best practice recommendations for state-transition modeling. These recommendations are directed both to modelers and to users of modeling results such as clinicians, clinical guideline developers, manufacturers, or policymakers. PMID:22999130

  5. IDENTIFICATION OF EXAMPLES OF GOOD PRACTICE IN ABSORPTION OF STRUCTURAL FUNDS, CASE STUDY PROJECT "CHRISTIAN DAY CENTER"

    Directory of Open Access Journals (Sweden)

    CEAUSESCU IONUT

    2016-08-01

    Full Text Available The main purpose of this study is to capture the practical point of view, the main issues in examples of best practices in the application for funding for the project "Christian Day Center- Support for young people and adults with disabilities" project benefited the City Council Târgu Jiu, is a project which was realized in the Regional Operational Programme, Priority Axis 3 DMI 3.2 - "Rehabilitation / modernization / development and equipping of social services", the total value of the project was 3,373,722.72 lei, of which non-repayable funding over was worth 2,592,251.08 lei. Through its general objective, the project "Day Center Christian - Support for young people and adults with disabilities" aims to contribute to improving the quality of infrastructure for social services by ensuring equal access of citizens of Tg-Jiu such services. Christian Day Center- support for young people and adults with physical disabilities, musculoskeletal, neuro, somatic and visual has already proposed to the idea of the project, to be a center which will ensure the social inclusion of these vulnerable and contribute to increasing the quality of life, improve communication and information on the rights and benefits of social services to improve the management and organization of the system of providing social services and facilitating the participation of all stakeholders in the development of social services.

  6. On the use of the THERP methodology in the human reliability analysis of nuclear power plants - compliance with the USNRC good practices criteria

    Energy Technology Data Exchange (ETDEWEB)

    Alvarenga, Marco Antonio Bayout; Fonseca, Renato Alves [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)]. E-mails: bayout@cnen.gov.br; rfonseca@cnen.gov.br

    2007-07-01

    THERP is largely used by the industry in general, mainly by the nuclear industry. This methodology belongs to the group of the human reliability first generation methodologies. However, in spite of the enormous contribution of these methodologies for the understanding of the subjects related to the human reliability, they present a variety of deficiencies that were identified along the history of practical application to the industrial projects. Considering the state-of-art in the analyses of these deficiencies, it was elaborated a set of good practices to be fulfilled by all methods of human reliability. This set of good practices is described in the recent documents of USNRC, NUREGs 1792 and 1842, of April 2005 and February 2006, respectively. In this article, the authors discuss the main technical deficiencies of the THERP methodology, when compared with the good practices criteria from USNRC. They point also possible solutions to eliminate such deficiencies. Many of these solutions can only be accomplished, in the authors' opinion, with the use of methodologies of second generation. We can mention four, among them, that stand out due the complexity and comprehension in the treatment of the subjects of human reliability. These four methodologies are denominated ATHEANA, CREAM, CAHR and DYLAM. The authors present a concise comparison between two of these four approaches and identify the main characteristics of each one in the attempt of solving the deficiencies of the THERP methodology. In this comparison, a revision of the technical literature was used, considering some of the main specialists in the area. (author)

  7. On the use of the THERP methodology in the human reliability analysis of nuclear power plants - compliance with the USNRC good practices criteria

    International Nuclear Information System (INIS)

    THERP is largely used by the industry in general, mainly by the nuclear industry. This methodology belongs to the group of the human reliability first generation methodologies. However, in spite of the enormous contribution of these methodologies for the understanding of the subjects related to the human reliability, they present a variety of deficiencies that were identified along the history of practical application to the industrial projects. Considering the state-of-art in the analyses of these deficiencies, it was elaborated a set of good practices to be fulfilled by all methods of human reliability. This set of good practices is described in the recent documents of USNRC, NUREGs 1792 and 1842, of April 2005 and February 2006, respectively. In this article, the authors discuss the main technical deficiencies of the THERP methodology, when compared with the good practices criteria from USNRC. They point also possible solutions to eliminate such deficiencies. Many of these solutions can only be accomplished, in the authors' opinion, with the use of methodologies of second generation. We can mention four, among them, that stand out due the complexity and comprehension in the treatment of the subjects of human reliability. These four methodologies are denominated ATHEANA, CREAM, CAHR and DYLAM. The authors present a concise comparison between two of these four approaches and identify the main characteristics of each one in the attempt of solving the deficiencies of the THERP methodology. In this comparison, a revision of the technical literature was used, considering some of the main specialists in the area. (author)

  8. Defining the role of University of Kentucky HealthCare in its medical market--how strategic planning creates the intersection of good public policy and good business practices.

    Science.gov (United States)

    Karpf, Michael; Lofgren, Richard; Bricker, Timothy; Claypool, Joseph O; Zembrodt, Jim; Perman, Jay; Higdon, Courtney M

    2009-02-01

    In response both to national pressures to reduce costs and improve health care access and outcomes and to local pressures to become a top-20 public research university, the University of Kentucky moved toward an integrated clinical enterprise, UK HealthCare, to create a common vision, shared goals, and an effective decision-making process. The leadership formed the vision and then embarked on a comprehensive and coordinated planning process that addressed financial, clinical, academic, and operational issues. The authors describe in depth the strategic planning process and specifically the definition of UK HealthCare's role in its medical marketplace. They began a rigorous process to assess and develop goals for the clinical programs and followed the progress of these programs through meetings driven by data and attended by the organization's senior leadership. They describe their approach to working with rural and community hospitals throughout central, eastern, and southern Kentucky to support the health care infrastructure of the state. They review the early successes of their strategic approach and describe the lessons they learned. The clinical successes have led to academic gains. The experience of UK HealthCare suggests that good business practices and good public policy are synergistic.

  9. Measurement of the thermal conductivity and heat transfer coefficient of a binary bed of beryllium pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Donne, M.D.; Piazza, G. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Inst. fuer Neutronenphysik und Reaktortechnik; Goraieb, A.; Sordon, G.

    1998-01-01

    The four ITER partners propose to use binary beryllium pebble bed as neutron multiplier. Recently this solution has been adopted for the ITER blanket as well. In order to study the heat transfer in the blanket the effective thermal conductivity and the wall heat transfer coefficient of the bed have to be known. Therefore at Forschungszentrum Karlsruhe heat transfer experiments have been performed with a binary bed of beryllium pebbles and the results have been correlated expressing thermal conductivity and wall heat transfer coefficients as a function of temperature in the bed and of the difference between the thermal expansion of the bed and of that of the confinement walls. The comparison of the obtained correlations with the data available from the literature show a quite good agreement. (author)

  10. Proceedings of the Canadian Dam Association 2004 annual conference : guidance to good practice. CD-ROM ed.

    International Nuclear Information System (INIS)

    This conference provided a forum to share the dam industry's best practices and promote discussion to improve the management and safety of dams. The discussions provided details on large hydropower development projects, their innovations in environmental impact assessment, mitigation, and monitoring. The conference included a technical component lead by experts on dams and tailings facilities. Recent developments in dam construction were reviewed along with discharge and debris management, tailings dam issues, asset management, seismic issues, emergency preparedness planning, public safety, seepage monitoring, flow control, dam rehabilitation, concrete testing, hydrotechnical issues, risk assessment methodology, and safety guidelines. The conference featured 46 presentations, of which 40 have been catalogued separately for inclusion in this database. refs., tabs., figs

  11. 'God grant it may do good two all': the madhouse practice of Joseph Mason, 1738-79.

    Science.gov (United States)

    Smith, Leonard

    2016-06-01

    Private madhouses made a significant contribution to the development of psychiatric practices in eighteenth-century England. Joseph Mason of Bristol, proprietor of a madhouse at Stapleton and then at nearby Fishponds, was part of a dynasty of successful and respected mad-doctors. A deeply religious man, his Christian ethics constituted the guiding force in his work with patients and interactions with their relatives. He was also an astute man of business, who recognized that comfortable domestic surroundings and the achievement of recoveries would enhance his reputation and attract lucrative middle-class custom. His treatment approaches, illustrated in a 1763 diary, were eclectic and pragmatic, comprising various medicines, dietary regulation, graded social interactions, and the cultivation of individualized therapeutic relationships with his patients.

  12. 'God grant it may do good two all': the madhouse practice of Joseph Mason, 1738-79.

    Science.gov (United States)

    Smith, Leonard

    2016-06-01

    Private madhouses made a significant contribution to the development of psychiatric practices in eighteenth-century England. Joseph Mason of Bristol, proprietor of a madhouse at Stapleton and then at nearby Fishponds, was part of a dynasty of successful and respected mad-doctors. A deeply religious man, his Christian ethics constituted the guiding force in his work with patients and interactions with their relatives. He was also an astute man of business, who recognized that comfortable domestic surroundings and the achievement of recoveries would enhance his reputation and attract lucrative middle-class custom. His treatment approaches, illustrated in a 1763 diary, were eclectic and pragmatic, comprising various medicines, dietary regulation, graded social interactions, and the cultivation of individualized therapeutic relationships with his patients. PMID:26837815

  13. Implementation of HSE Linear Training Good Practice%实施HSE直线培训的良好实践

    Institute of Scientific and Technical Information of China (English)

    张莉

    2012-01-01

    Shandong Haihua Group with their own characteristics to establish a distinctive HSE management models,in terms of training taken straight training way.Through in last few years practice,obtained better HSE performance,has accumulated some experience in HSE management,with a view to other large enterprise HSE management to provide reference.%山东海化集团结合本身特点建立了具有特色HSE管理模式,在培训方面采取了直线培训的方式。通过公司近几年来的实践,取得较好HSE绩效,积累了一些HSE管理经验,以期对其它大型企业集团HSE管理提供参考。

  14. Health care for immigrants in Europe: Is there still consensus among country experts about principles of good practice? A Delphi study

    Directory of Open Access Journals (Sweden)

    Soares Joaquim JF

    2011-09-01

    Full Text Available Abstract Background European Member States are facing a challenge to provide accessible and effective health care services for immigrants. It remains unclear how best to achieve this and what characterises good practice in increasingly multicultural societies across Europe. This study assessed the views and values of professionals working in different health care contexts and in different European countries as to what constitutes good practice in health care for immigrants. Methods A total of 134 experts in 16 EU Member States participated in a three-round Delphi process. The experts represented four different fields: academia, Non-Governmental Organisations, policy-making and health care practice. For each country, the process aimed to produce a national consensus list of the most important factors characterising good practice in health care for migrants. Results The scoring procedures resulted in 10 to 16 factors being identified as the most important for each participating country. All 186 factors were aggregated into 9 themes: (1 easy and equal access to health care, (2 empowerment of migrants, (3 culturally sensitive health care services, (4 quality of care, (5 patient/health care provider communication, (6 respect towards migrants, (7 networking in and outside health services, (8 targeted outreach activities, and (9 availability of data about specificities in migrant health care and prevention. Although local political debate, level of immigration and the nature of local health care systems influenced the selection and rating of factors within each country, there was a broad European consensus on most factors. Yet, discordance remained both within countries, e.g. on the need for prioritising cultural differences, and between countries, e.g. on the need for more consistent governance of health care services for immigrants. Conclusions Experts across Europe asserted the right to culturally sensitive health care for all immigrants. There is a

  15. Assessment of beryllium Faraday screens of the JET ICRF antennas

    International Nuclear Information System (INIS)

    The JET ICRF antennas, equipped with beryllium (Be) Faraday screens (FS), can be operated in such a way that the RF specific effects on the plasma boundary, by the impurity influx originating at the screens, are reduced to a negligible level. In dipole phasing, k parallel = 7 m-1, the influx is for all purposes negligible. In monopole phasing (kparallel = 0 m-1) the beryllium influx does not exceed ΦFSBe = 1 x 1019 atoms·MW-1·s-1 and the corresponding δZeff/PRF is -1. The observed dependences of ΦFSBe (in monopole phasing) on plasma density, antenna voltage, antenna phasing, and the angle between FS elements and the magnetic field in the boundary, B-vector(a) = B-vectorθ(a) + B-vectorT(a), confirm that the release mechanism is sputtering by ions accelerated in the RF enhanced Bohm-Debye sheaths forming at the front face of the FS. When the angle between FS and B-vector(a) is approx. 22 deg. C, the fraction of the RF power radiated by the antenna, dissipated at the screen, can reach 40%. At high antenna voltage, arcing across the FS can occur. With dipole phasing the heating efficiency is not degraded, even with the large angle, and all the power coupled by the antenna is absorbed at the resonance position near the plasma centre. The open screen design did not introduce any disadvantages. The experience from JET operation at powers of up to 22 MW shows that, if the necessary conditions are met, i.e. if RF rectification is minimized, antennas are phased as dipoles and material with low sputtering coefficients at energies of 0.5-1 keV is used, then the influx from the FS is, for all practical purposes, eliminated. (author). 19 refs, 6 figs

  16. International survey of methods used in health technology assessment (HTA: does practice meet the principles proposed for good research?

    Directory of Open Access Journals (Sweden)

    Stephens JM

    2012-08-01

    Full Text Available Jennifer M Stephens,1 Bonnie Handke,2 Jalpa A Doshi3 On behalf of the HTA Principles Working Group, part of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR HTA Special Interest Group (SIG1Pharmerit International, Bethesda, MD, USA; 2Medtronic Neuromodulation, Minneapolis, MN, USA; 3Center for Evidence-Based Practice and Center for Health Incentives and Behavioral Economics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USAObjective: To describe research methods used internationally in health technology assessment (HTA and health-care reimbursement policies; compare the survey findings on research methods and processes to published HTA principles; and discuss important issues/trends reported by HTA bodies related to current research methods and applications of the HTA process.Methods: Representatives from HTA bodies worldwide were recruited to complete an online survey consisting of 47 items within four topics: (1 organizational information and process, (2 primary HTA methodologies and importance of attributes, (3 HTA application and dissemination, and (4 quality of HTA, including key issues. Results were presented as a comparison of current HTA practices and research methods to published HTA principles.Results: The survey was completed by 30 respondents representing 16 countries in five major regions, Australia (n = 3, Canada (n = 2, Europe (n = 17, Latin America (n = 2, and the United States (n = 6. The most common methodologies used were systematic review, meta-analysis, and economic modeling. The most common attributes evaluated were effectiveness (more commonly than efficacy, cost-effectiveness, safety, and quality of life. The attributes assessed, relative importance of the attributes, and conformance with HTA principles varied by region/country. Key issues and trends facing HTA bodies included standardizing methods for economic evaluations and grading of evidence, lack of evidence

  17. Three Myths About Dietary Supplements … and How Knowing the Right Answers Is Good for Your Integrative Medicine Practice.

    Science.gov (United States)

    Israelsen, Loren; Lampe, Frank

    2016-06-01

    The use of safe and beneficial dietary supplements remains an important part of your patients' healthy lifestyle-and supplements are likely an important part of your integrative medicine practice. Although issues surrounding potency, ingredient identification, adulteration, and the enforcement of existing laws are legitimate concerns for medical professionals and consumers, the responsible industry is actively working to raise quality standards for its products through a number of self-regulatory measures. These include education about and adoption of additional quality assurance initiatives, such as GMPs for botanical ingredients; better supply-chain management; adoption of improved identification and testing methodologies; an industry-wide product registry; the use of accredited third-party certifications and seals; and initiatives to promote widespread membership in the industry's trade associations, which is a reliable indicator of a company's support of and adherence to strict quality guidelines. Also, industry support of appropriate enforcement actions against problem players and products from the US Food and Drug Administration (FDA), the Federal Trade Commission (FTC), and states' attorneys general continues in an effort to rid the market of unsafe and mislabeled products. PMID:27547162

  18. Experiments on studying beryllium - steam interaction, determination of oxidated beryllium emissivity factor

    International Nuclear Information System (INIS)

    The report presents results of beryllium emissivity factor measurements within 700-1300 K temperature range. The tests were conducted at Institute of Atomic Energy of the National Nuclear Center of the Republic of Kazakhstan to receive experimental data for verification of calculation programs describing an accident involving water coolant discharge into ITER reactor vacuum cavity. (author)

  19. Beryllium toxicity testing in the suspension culture of mouse fibroblasts.

    Science.gov (United States)

    Rössner, P; Bencko, V

    1980-01-01

    Suspension culture of mouse fibroblast cell line L-A 115 was used to test beryllium toxicity in the presence of magnesium ions. Beryllium added to the MEM cultivation medium was bound in a complex with sulphosalicylic acid BeSSA complex, because the use of beryllium chloride turned out to yield ineffective beryllium phosphate that formed macroscopically detectable insoluble opacities. The BeSSA complex was used in the concentration range: 10(-3)--10(-9)M, magnesium was used in 3 concentrations: 10(-1)M, 5 x 10(-2)M and 10(-2)M. Growth curve analysis revealed pronounced beryllium toxicity at the concentration of 10(-3)M, magnesium-produced toxic changes were observed only at the concentration of 10(-1)M. No competition between the beryllium and magnesium ions was recorded. It is assumed that the possible beryllium-magnesium competition was significantly modified by the use of BeSSA complex-bound beryllium.

  20. Ionization energies of beryllium in strong magnetic fields

    Institute of Scientific and Technical Information of China (English)

    GUANXiao-xu; ZHANGYue-xia

    2004-01-01

    We have develop an effective frozen core approximation to calculate energy levels and ionization enegies of the beryllium atom in magnetic field strengths up to 2.35 × 105T. Systematic improvement over the Hartree-Fock results for the beryllium low-lying states has been accomplished.