WorldWideScience

Sample records for berkelium 250

  1. New berkelium isotope: 242Bk

    International Nuclear Information System (INIS)

    A new isotope of berkelium, 242Bk, was produced with a cross section of approx. 10 μb in reactions of boron on uranium and nitrogen on thorium. It decays by electron capture with a half-life of 7 +- 1.3 minutes. The branching ratio for this isotope for alpha decay is less than 1% and that for spontaneous fission is less than 0.03%. 2 figures, 2 tables

  2. Characterization of berkelium(III) dipicolinate and borate compounds in solution and the solid state.

    Science.gov (United States)

    Silver, Mark A; Cary, Samantha K; Johnson, Jason A; Baumbach, Ryan E; Arico, Alexandra A; Luckey, Morgan; Urban, Matthew; Wang, Jamie C; Polinski, Matthew J; Chemey, Alexander; Liu, Guokui; Chen, Kuan-Wen; Van Cleve, Shelley M; Marsh, Matthew L; Eaton, Teresa M; van de Burgt, Lambertus J; Gray, Ashley L; Hobart, David E; Hanson, Kenneth; Maron, Laurent; Gendron, Frédéric; Autschbach, Jochen; Speldrich, Manfred; Kögerler, Paul; Yang, Ping; Braley, Jenifer; Albrecht-Schmitt, Thomas E

    2016-08-26

    Berkelium is positioned at a crucial location in the actinide series between the inherently stable half-filled 5f(7) configuration of curium and the abrupt transition in chemical behavior created by the onset of a metastable divalent state that starts at californium. However, the mere 320-day half-life of berkelium's only available isotope, (249)Bk, has hindered in-depth studies of the element's coordination chemistry. Herein, we report the synthesis and detailed solid-state and solution-phase characterization of a berkelium coordination complex, Bk(III)tris(dipicolinate), as well as a chemically distinct Bk(III) borate material for comparison. We demonstrate that berkelium's complexation is analogous to that of californium. However, from a range of spectroscopic techniques and quantum mechanical calculations, it is clear that spin-orbit coupling contributes significantly to berkelium's multiconfigurational ground state. PMID:27563098

  3. ACC 250 Tutorials / acc250dotcom

    OpenAIRE

    modumteja

    2015-01-01

    For more course tutorials visit www.acc250.com   ACC 250 Week 1 CheckPoint Choosing Accounting Software ACC 250 Week 1 Assignment Accounting Software Memo ACC 250 Week 2 CheckPoint Bellwether Garden Supply Back Up and Restore Data ACC 250 Week 2 DQ 1 and DQ 2 ACC 250 Week 3 CheckPoint Bellwether Garden Supply Vendor Transactions ACC 250 Week 3 Assignment Bellwether Garden Supply Record a Transaction ACC 250 Week 4 CheckPoint Bellwether Garden Supply Pa...

  4. ACC 250 UOP Tutorial / Uoptutorial

    OpenAIRE

    Ben K. Green

    2015-01-01

    For more course tutorials visit www.uoptutorial.com   ACC 250 Week 1 CheckPoint Choosing Accounting Software ACC 250 Week 1 Assignment Accounting Software Memo ACC 250 Week 2 CheckPoint Bellwether Garden Supply Back Up and Restore Data ACC 250 Week 2 DQ 1 and DQ 2 ACC 250 Week 3 CheckPoint Bellwether Garden Supply Vendor Transactions ACC 250 Week 3 Assignment Bellwether Garden Supply Record a Transaction ACC 250 Week 4 CheckPoint Bellwether Garden Supp...

  5. ACC 250 UOP Courses / uoptutorial

    OpenAIRE

    hani

    2015-01-01

    For more course tutorials visit www.uoptutorial.com     ACC 250 Week 1 CheckPoint Choosing Accounting Software ACC 250 Week 1 Assignment Accounting Software Memo ACC 250 Week 2 CheckPoint Bellwether Garden Supply Back Up and Restore Data ACC 250 Week 2 DQ 1 and DQ 2 ACC 250 Week 3 CheckPoint Bellwether Garden Supply Vendor Transactions ACC 250 Week 3 Assignment Bellwether Garden Supply Record a Transaction ACC 250 Week 4 CheckPoint Bellwether...

  6. ACC 250 UOP TUTORIAL / Uoptutorial

    OpenAIRE

    Cherry

    2015-01-01

    For more course tutorials visit www.uoptutorial.com   ACC 250 Week 1 CheckPoint Choosing Accounting Software ACC 250 Week 1 Assignment Accounting Software Memo ACC 250 Week 2 CheckPoint Bellwether Garden Supply Back Up and Restore Data ACC 250 Week 2 DQ 1 and DQ 2 ACC 250 Week 3 CheckPoint Bellwether Garden Supply Vendor Transactions ACC 250 Week 3 Assignment Bellwether Garden Supply Record a Transaction ACC 250 Week 4 CheckPoint Bellwether Garden Sup...

  7. HTT 250 UOP Coureses/UOP Help

    OpenAIRE

    royal8

    2015-01-01

    HTT 250 Entire Course For more course tutorials visit www.uophelp.com     HTT 250 Week 1 Assignment: Organization Chart Hotel Front Office HTT 250 Week 1 CheckPoint: Total Quality Management HTT 250 Week 1 CheckPoint: Lodging Properties HTT 250 Week 2 CheckPoint: Hotel Price Comparison HTT 250 Week 2 DQs HTT 250 Week 3 CheckPoint: Average Daily Rate HTT 250 Week 4 CheckPoint: Front Office FAQs HTT 250 Week 4 DQs HTT 250 Week 5 Assi...

  8. ACC 250 UOP Tutorial/Uoptutorial

    OpenAIRE

    Giselle Isabel

    2015-01-01

    ACC 250 Week 1 CheckPoint Choosing Accounting Software ACC 250 Week 1 Assignment Accounting Software Memo ACC 250 Week 2 CheckPoint Bellwether Garden Supply Back Up and Restore Data ACC 250 Week 2 DQ 1 and DQ 2 ACC 250 Week 3 CheckPoint Bellwether Garden Supply Vendor Transactions ACC 250 Week 3 Assignment Bellwether Garden Supply Record a Transaction ACC 250 Week 4 CheckPoint Bellwether Garden Supply Payroll ACC 250 Week 4 DQ 1 and DQ 2 ACC 250 Week 5 CheckPoi...

  9. ACC 250 UOP COURSE TUTORIAL/ UOPHELP

    OpenAIRE

    veeru1

    2015-01-01

    For more course tutorials visit www.uophelp.com   ACC 250 Week 1 CheckPoint Choosing Accounting Software ACC 250 Week 1 Assignment Accounting Software Memo ACC 250 Week 2 CheckPoint Bellwether Garden Supply Back Up and Restore Data ACC 250 Week 2 DQ 1 and DQ 2 ACC 250 Week 3 CheckPoint Bellwether Garden Supply Vendor Transactions ACC 250 Week 3 Assignment Bellwether Garden Supply Record a Transaction ACC 250 Week 4 CheckPoint Bellwether Garden Supply P...

  10. 48 CFR 1846.673 - Distribution of DD Forms 250 and 250c.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Distribution of DD Forms... Reports 1846.673 Distribution of DD Forms 250 and 250c. (a) DD Forms 250 and 250c shall be distributed in accordance with installation procedures. (b) The contractor is responsible for distributing DD Forms 250...

  11. 21 CFR 172.250 - Petroleum naphtha.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Petroleum naphtha. 172.250 Section 172.250 Food and..., Films and Related Substances § 172.250 Petroleum naphtha. Petroleum naphtha may be safely used in food..., essentially paraffinic and naphthenic in nature obtained from petroleum, (b) The additive is refined to...

  12. 30 CFR 250.604 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.604 Section 250.604... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.604 Hydrogen sulfide. When a well-workover operation is conducted in zones known to contain hydrogen sulfide (H2S) or...

  13. 30 CFR 250.808 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.808 Section 250.808... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Safety Systems § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in zones where the presence of...

  14. 30 CFR 250.490 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.490 Section 250.490... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Hydrogen Sulfide § 250.490 Hydrogen... black lettering as follows: Letter height Wording 12 inches Danger. Poisonous Gas. Hydrogen Sulfide....

  15. 30 CFR 250.504 - Hydrogen sulfide.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.504 Section 250.504... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.504 Hydrogen sulfide. When a well-completion operation is conducted in zones known to contain hydrogen sulfide (H2S) or...

  16. 32 CFR 250.6 - Responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 250.6 Section 250.6 National... WITHHOLDING OF UNCLASSIFIED TECHNICAL DATA FROM PUBLIC DISCLOSURE § 250.6 Responsibilities. (a) The Under Secretary of Defense for Research and Engineering (USDR&E) shall have overall responsibility for...

  17. 49 CFR 250.3 - Fees.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Fees. 250.3 Section 250.3 Transportation Other... TRANSPORTATION GUARANTEE OF CERTIFICATES OF TRUSTEES OF RAILROADS IN REORGANIZATION § 250.3 Fees. On date of... Administrator as a guarantee fee such amount as the Administrator hereafter may determine and prescribe...

  18. 45 CFR 2541.250 - Program income.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Program income. 2541.250 Section 2541.250 Public... Post-Award Requirements § 2541.250 Program income. (a) General. Grantees are encouraged to earn income to defray program costs. Program income includes income from fees for services performed, from...

  19. 21 CFR 73.250 - Fruit juice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Fruit juice. 73.250 Section 73.250 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.250 Fruit juice. (a) Identity. (1) The color additive fruit juice is prepared either by expressing the juice from mature varieties of fresh, edible fruits, or...

  20. 8 CFR 250.1 - Application.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Application. 250.1 Section 250.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.1 Application. Application for removal shall be made on Form I-243. No appeal shall lie...

  1. 7 CFR 65.250 - Slaughter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Slaughter. 65.250 Section 65.250 Agriculture..., PEANUTS, AND GINSENG General Provisions Definitions § 65.250 Slaughter. Slaughter means the point in which a livestock animal (including chicken) is prepared into meat products (covered commodities)...

  2. 30 CFR 250.300 - Pollution prevention.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Pollution prevention. 250.300 Section 250.300... OPERATIONS IN THE OUTER CONTINENTAL SHELF Pollution Prevention and Control § 250.300 Pollution prevention. (a... components which could cause unreasonable degradation to the marine environment. No...

  3. 7 CFR 250.2 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 250.2 Section 250.2 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General § 250.2 Administration. (a) Delegation to FNS. Within the Department, FNS shall act on behalf of the Department in the administration of...

  4. 30 CFR 250.1632 - Production rates.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Production rates. 250.1632 Section 250.1632 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1632 Production rates. Each...

  5. 30 CFR 250.1633 - Production measurement.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Production measurement. 250.1633 Section 250... SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1633 Production measurement. (a) General. Measurement equipment and security procedures shall be designed, installed, used, maintained,...

  6. 48 CFR 1846.672 - Preparing DD Forms 250 and 250c.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Preparing DD Forms 250 and 250c. 1846.672 Section 1846.672 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... DD Forms 250 and 250c....

  7. 21 CFR 74.250 - Orange B.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Orange B. 74.250 Section 74.250 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Foods § 74.250 Orange B. (a) Identity. (1) The color additive Orange B is principally the disodium salt of...

  8. 40 CFR 35.250 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program Implementation Cooperative Agreements to States (as defined in section 2 of Federal Insecticide, Fungicide, and...

  9. 5 CFR 250.203 - Agency responsibilities.

    Science.gov (United States)

    2010-01-01

    ... 250.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in the assessment of the management of human capital in the Federal Government, and to help meet...

  10. 30 CFR 250.1203 - Gas measurement.

    Science.gov (United States)

    2010-07-01

    ... CFR 250.198. (3) Ensure that the measurement components demonstrate consistent levels of accuracy... recorder is used, you must follow the recommendations in API MPMS as referenced in 30 CFR 250.198. (5) Take.... 1713 and 30 CFR part 212. (5) Upon the request of the Regional Supervisor, you must provide copies...

  11. English 304 & Communications 250: Professional Rhetorics

    Science.gov (United States)

    Hodgson, Justin

    2009-01-01

    This article provides a course overview of English 304 & Communications 250: Professional Rhetorics. This course was a pilot project instituted at Clemson University in spring of 2008. The project integrally linked English 304 (Business Writing) and Communications 250 (Public Speaking), requiring the same students to be enrolled in both 3…

  12. 36 CFR 2.50 - Special events.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  13. 7 CFR 250.21 - Civil rights.

    Science.gov (United States)

    2010-01-01

    ... rights. Distributing agencies, subdistributing agencies and recipient agencies shall comply with the Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil rights... 7 Agriculture 4 2010-01-01 2010-01-01 false Civil rights. 250.21 Section 250.21...

  14. HTT 250 uop course tutorial/uop helP

    OpenAIRE

    baily

    2015-01-01

    HTT 250 Week 1 Assignment: Organization Chart Hotel Front Office HTT 250 Week 1 CheckPoint: Total Quality Management HTT 250 Week 1 CheckPoint: Lodging Properties HTT 250 Week 2 CheckPoint: Hotel Price Comparison HTT 250 Week 2 DQs HTT 250 Week 3 CheckPoint: Average Daily Rate HTT 250 Week 4 CheckPoint: Front Office FAQs HTT 250 Week 4 DQs HTT 250 Week 5 Assignment: Night Audit Application HTT 250 Week 5 CheckPoint: Night Audit HTT 250 Week 6 CheckPoint...

  15. 30 CFR 250.1201 - Definitions.

    Science.gov (United States)

    2010-07-01

    ...) from gas, including absorption, adsorption, or refrigeration. Processing does not include treatment... applicable chapter of the API MPMS, which is incorporated by reference in 30 CFR 250.198. Terms used...

  16. 7 CFR 1726.250 - General.

    Science.gov (United States)

    2010-01-01

    ... ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Modifications to RUS Standard Contract Forms § 1726.250 General. RUS provides standard forms of contract for the procurement of materials, equipment, and construction and for contract amendments and various related forms for use by RUS borrowers. See § 1726.304...

  17. 40 CFR 264.250 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.250... treat hazardous waste in piles, except as § 264.1 provides otherwise. (b) The regulations in...

  18. 7 CFR 250.15 - Financial management.

    Science.gov (United States)

    2010-01-01

    ... Uniform Federal Assistance Regulations, 7 CFR part 3015, subpart T. In no case may distribution charges be... under the cost Principles in the Department's Uniform Federal Assistance Regulations, 7 CFR part 3015... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management. 250.15 Section...

  19. Johann Wilhelm Krause 250 / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2007-01-01

    Eesti klassitsistliku arhitektuuri suurkuju ning Tartu Ülikooli arhitekti Johann Wilhelm Krause 250. sünniaastapäeva tähistati näitustega Tallinnas ja Tartus. Tartu Ülikooli raamatukogu kunstikogusse kuulub ligi 700 J. W. Krause loodud joonistust

  20. 40 CFR 265.250 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... Piles § 265.250 Applicability. The regulations in this subpart apply to owners and operators of facilities that treat or store hazardous waste in piles, except as § 265.1 provides otherwise. Alternatively, a pile of hazardous waste may be managed as a landfill under subpart N....

  1. Dicty_cDB: CFD250 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF (Link to library) CFD250 (Link to dictyBase) - - - Contig-U16455-1 CFD250P (Link to Original site) CFD...250F 566 CFD250Z 716 CFD250P 1282 - - Show CFD250 Library CF (Link to library) Clone ID CFD...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CF/CFD2-C/CFD250Q.Seq.d/ Representative seq. ID CFD...250P (Link to Original site) Representative DNA sequence >CFD250 (CFD250Q) /CSM/CF/CFD2-C/CFD...hqinrqespr*sr**ercccxskxeinx*k k Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value CFD250 (CFD

  2. From ANAIS-25 towards ANAIS-250

    CERN Document Server

    Amaré, J; Cuesta, C; García, E; Ginestra, C; Martínez, M; Oliván, M A; Ortigoza, Y; de Solórzano, A Ortiz; Pobes, C; Puimedón, J; Sarsa, M L; Villar, J A; Villar, P

    2014-01-01

    The ANAIS (Annual modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory (LSC). 250 kg of ultra pure NaI(Tl) crystals will be used as target, divided into 20 modules, 12.5 kg mass each, and coupled to two high e?ciency photomultiplier tubes from Hamamatsu. The ANAIS-25 set-up at the LSC consists of two prototypes, amounting 25 kg NaI(Tl), grown from a powder having a potassium level under the limit of our analytical techniques, and installed in a convenient shielding at the LSC. The background has been carefully analyzed and main results will be summarized in this paper, focusing on the alpha contamination identified in the prototypes and the related background contributions. Status of fulfillment of ANAIS experimental goals and prospects for the building of ANAIS-250 experiment will be also revised.

  3. Hydrolysis and formation constants at 250C

    International Nuclear Information System (INIS)

    A database consisting of hydrolysis and formation constants for about 20 metals associated with the disposal of nuclear waste is given. Complexing ligands for the various ionic species of these metals include OH, F, Cl, SO4, PO4 and CO3. Table 1 consists of tabulated calculated and experimental values of log K/sub xy/, mainly at 250C and various ionic strengths together with references to the origin of the data. Table 2 consists of a column of recommended stability constants at 250C and zero ionic strength tabulated in the column headed log K/sub xy/(0); other columns contain coefficients for an extended Debye-Huckel equation to permit calculations of stability constants up to 3 ionic strength, and up to 0.7 ionic strength using the Davies equation. Selected stability constants calculated with these coefficients for various ionic strengths agree to an average of +- 2% when compared with published experimental and calculated values

  4. ACCELERATING POLARIZED PROTONS TO 250 GEV

    Energy Technology Data Exchange (ETDEWEB)

    BAI,M.; AHRENS, L.; ALEKSEEV, I.G.; ALESSI, J.; BEEBE-WANG, J.; ET AL.

    2007-06-25

    The Relativistic Heavy Ion Collider (RHIC) as the first high energy polarized proton collider was designed t o provide polarized proton collisions a t a maximum beam energy of 250 GeV. I t has been providing collisions a t a beam energy of 100 Gel' since 2001. Equipped with two full Siberian snakes in each ring, polarization is preserved during the acceleration from injection to 100 GeV with careful control of the betatron tunes and the vertical orbit distortions. However, the intrinsic spin resonances beyond 100 GeV are about a factor of two stronger than those below 100 GeV? making it important t o examine the impact of these strong intrinsic spin resonances on polarization survival and the tolerance for vertical orbit distortions. Polarized protons were accelerated t o the record energy of 250 GeV in RHIC with a polarization of 46% measured a t top energy in 2006. The polarization measurement as a function of beam energy also shows some polarization loss around 136 GeV, the first strong intrinsic resonance above 100 GeV. This paper presents the results and discusses the sensitivity of the polarization survival t o orbit distortions.

  5. Dicty_cDB: SSI250 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 250Z (Link to Original site) - - SSI250Z 697 - - - - Show SSI250 Library SS (Link to library) Clone ID SSI...Representative seq. ID SSI250Z (Link to Original site) Representative DNA sequence >SSI250 (SSI250Q) /CSM/SS/SSI2-C/SSI...I*inpyqnfytgnq Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value SSI...SS (Link to library) SSI250 (Link to dictyBase) - G00812 DDB0231535 Contig-U05055-1 SSI...250 (Link to dictyBase) Atlas ID - NBRP ID G00812 dictyBase ID DDB0231535 Link to Contig Contig-U05055-1 Original si

  6. 41 CFR 60-250.68 - Reinstatement of ineligible contractors.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Reinstatement of ineligible contractors. 60-250.68 Section 60-250.68 Public Contracts and Property Management Other Provisions... OTHER PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.68 Reinstatement...

  7. 41 CFR 60-250.65 - Enforcement proceedings.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Enforcement proceedings. 60-250.65 Section 60-250.65 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.65 Enforcement proceedings....

  8. 41 CFR 60-250.63 - Violation of conciliation agreements.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Violation of conciliation agreements. 60-250.63 Section 60-250.63 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.63 Violation of...

  9. 41 CFR 60-250.62 - Conciliation agreements.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Conciliation agreements. 60-250.62 Section 60-250.62 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.62 Conciliation agreements. If...

  10. 41 CFR 60-250.61 - Complaint procedures.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaint procedures. 60-250.61 Section 60-250.61 Public Contracts and Property Management Other Provisions Relating to Public... VETERANS General Enforcement and Complaint Procedures § 60-250.61 Complaint procedures. (a) Place and...

  11. 41 CFR 60-250.60 - Compliance evaluations.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Compliance evaluations. 60-250.60 Section 60-250.60 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.60 Compliance evaluations....

  12. 41 CFR 60-250.67 - Notification of agencies.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Notification of agencies. 60-250.67 Section 60-250.67 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.67 Notification of agencies....

  13. 41 CFR 60-250.66 - Sanctions and penalties.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Sanctions and penalties. 60-250.66 Section 60-250.66 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.66 Sanctions and penalties....

  14. 41 CFR 60-250.69 - Intimidation and interference.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Intimidation and interference. 60-250.69 Section 60-250.69 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.69 Intimidation and...

  15. 7 CFR 250.68 - Nutrition Services Incentive Program (NSIP).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nutrition Services Incentive Program (NSIP). 250.68 Section 250.68 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... Donated Food Outlets § 250.68 Nutrition Services Incentive Program (NSIP). (a) Distribution of...

  16. 6 CFR 27.250 - Inspections and audits.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Inspections and audits. 27.250 Section 27.250 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.250 Inspections and audits. (a) Authority. In order...

  17. 30 CFR 250.1002 - Design requirements for DOI pipelines.

    Science.gov (United States)

    2010-07-01

    ... 30 CFR 250.198) where— P=Internal design pressure in pounds per square inch (psi). S=Specified..., API Spec 6A, or the equivalent (incorporated by reference as specified in 30 CFR 250.198). Each flange... Spec 17J, incorporated by reference as specified in 30 CFR 250.198. (5) You must design pipeline...

  18. 7 CFR 58.250 - Dry whole milk.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Dry whole milk. 58.250 Section 58.250 Agriculture... Products Bearing Usda Official Identification § 58.250 Dry whole milk. Dry whole milk in commercial bulk... Grades of Dry Whole Milk. Quality requirements for dry whole milk in consumer packages shall be for...

  19. 7 CFR 250.30 - State processing of donated foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false State processing of donated foods. 250.30 Section 250... of Donated Foods § 250.30 State processing of donated foods. (a) General. This section sets forth the... may enter into contracts for the processing of donated foods and prescribes the minimum...

  20. 31 CFR 250.6 - Powers of attorney.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Powers of attorney. 250.6 Section 250... SETTLEMENT COMMISSION OF THE UNITED STATES § 250.6 Powers of attorney. No power of attorney to sign a voucher application will be recognized but a power of attorney executed subsequent to the certification of an award...

  1. 30 CFR 250.302 - Definitions concerning air quality.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions concerning air quality. 250.302... Definitions concerning air quality. For purposes of §§ 250.303 and 250.304 of this part: Air pollutant means..., pursuant to section 109 of the Clean Air Act, national primary or secondary ambient air quality...

  2. 7 CFR 958.250 - Assessment Credit Report.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Assessment Credit Report. 958.250 Section 958.250... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Rules and Regulations § 958.250 Assessment Credit Report. Each handler may receive a credit for assessments on onions that have been levied in...

  3. 41 CFR 60-250.22 - Direct threat defense.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Direct threat defense. 60-250.22 Section 60-250.22 Public Contracts and Property Management Other Provisions Relating to Public... VETERANS Discrimination Prohibited § 60-250.22 Direct threat defense. The contractor may use as...

  4. 21 CFR 173.250 - Methyl alcohol residues.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Methyl alcohol residues. 173.250 Section 173.250... CONSUMPTION Solvents, Lubricants, Release Agents and Related Substances § 173.250 Methyl alcohol residues... oleoresins as a residue from the extraction of spice, at a level not to exceed 50 parts per million. (b)...

  5. 250 Years of the State Survey

    Directory of Open Access Journals (Sweden)

    Ivana Wechselberger

    2014-06-01

    Full Text Available The first topographic survey of the Habsburg Monarchy was decreed by Maria Theresa 250 years ago, on May 13, 1764. A conference was held on the occasion of the anniversary by the Austrian State Geodetic Administration (BEV – Bundesamt für Eich- und Vermessungswesen and the Institute for Military Geosciences (IMG – Institut für Militärisches Geowesen in Vienna on May 13 and 14, 2014. The conference was sort of a time travel through Austrian state surveys. Historical development and methods of the first three state surveys (18th and 19th century were presented on the first conference day. Lectures were held by representatives of Austrian scientific institutions and new countries of the Monarchy. The second conference day was dedicated to the 4th state survey (20th century and its impact on civilian and military application and economy.

  6. 21 CFR 137.250 - White corn meal.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false White corn meal. 137.250 Section 137.250 Food and... Related Products § 137.250 White corn meal. (a) White corn meal is the food prepared by so grinding... fiber content of the finished corn meal is not less than 1.2 percent and not more than that of...

  7. 30 CFR 250.510 - Diesel engine air intakes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Diesel engine air intakes. 250.510 Section 250... engine air intakes. Diesel engine air intakes must be equipped with a device to shut down the diesel engine in the event of runaway. Diesel engines that are continuously attended must be equipped...

  8. 30 CFR 250.610 - Diesel engine air intakes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Diesel engine air intakes. 250.610 Section 250... engine air intakes. No later than May 31, 1989, diesel engine air intakes shall be equipped with a device to shut down the diesel engine in the event of runaway. Diesel engines which are...

  9. 41 CFR 60-250.24 - Drugs and alcohol.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Drugs and alcohol. 60-250... VETERANS Discrimination Prohibited § 60-250.24 Drugs and alcohol. (a) Specific activities permitted. The contractor: (1) May prohibit the illegal use of drugs and the use of alcohol at the workplace by...

  10. 30 CFR 250.1616 - Supervision, surveillance, and training.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Supervision, surveillance, and training. 250.1616 Section 250.1616 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Supervision, surveillance, and training. (a) The lessee shall provide onsite supervision of...

  11. 33 CFR 105.250 - Security systems and equipment maintenance.

    Science.gov (United States)

    2010-07-01

    ... maintenance. 105.250 Section 105.250 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... systems and equipment maintenance. (a) Security systems and equipment must be in good working order and... include procedures for identifying and responding to security system and equipment failures...

  12. 30 CFR 250.1624 - Blowout prevention equipment.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Blowout prevention equipment. 250.1624 Section 250.1624 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND... prevention equipment. (a) The BOP system and system components and related well-control equipment shall...

  13. 30 CFR 250.615 - Blowout prevention equipment.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Blowout prevention equipment. 250.615 Section 250.615 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS... Blowout prevention equipment. (a) The BOP system, system components and related well-control...

  14. 30 CFR 250.515 - Blowout prevention equipment.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Blowout prevention equipment. 250.515 Section 250.515 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS... Blowout prevention equipment. (a) The BOP system and system components and related well-control...

  15. 30 CFR 250.101 - Authority and applicability.

    Science.gov (United States)

    2010-07-01

    ... 250.101 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Authority and Definition of Terms § 250... Management Service (MMS) to regulate oil, gas, and sulphur exploration, development, and...

  16. 21 CFR 333.250 - Labeling of antifungal drug products.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Labeling of antifungal drug products. 333.250... Antifungal Drug Products § 333.250 Labeling of antifungal drug products. (a) Statement of identity. The... “antifungal.” (b) Indications. The labeling of the product states, under the heading “Indications,” the...

  17. 42 CFR 447.250 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis and purpose. 447.250 Section 447.250 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... requires that payments be consistent with efficiency, economy, and quality of care; (c) Sections 447.253...

  18. 7 CFR 765.208-765.250 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false 765.208-765.250 Section 765.208-765.250 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN SERVICING-REGULAR Protecting the Agency's Security Interest §§...

  19. Superfund GIS - 1:250,000 Geology of Tennessee.

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set is a digital representation of the printed 1:250,000 geologic maps from the Tennessee Department of Environment and Conservation, Division of Geology....

  20. Alaska map quadrangles at 1:250,000 scale

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Outlines of 1:250,000 scale map quadrangles in Alaska for use as a geographic reference within Google Earth or other software capable of interpreting KML, with...

  1. Hybrid Propulsion Demonstration Program 250K Hybrid Motor

    Science.gov (United States)

    Story, George; Zoladz, Tom; Arves, Joe; Kearney, Darren; Abel, Terry; Park, O.

    2003-01-01

    The Hybrid Propulsion Demonstration Program (HPDP) program was formed to mature hybrid propulsion technology to a readiness level sufficient to enable commercialization for various space launch applications. The goal of the HPDP was to develop and test a 250,000 pound vacuum thrust hybrid booster in order to demonstrate hybrid propulsion technology and enable manufacturing of large hybrid boosters for current and future space launch vehicles. The HPDP has successfully conducted four tests of the 250,000 pound thrust hybrid rocket motor at NASA's Stennis Space Center. This paper documents the test series.

  2. New model for the lunar interior to 250 km

    International Nuclear Information System (INIS)

    A new model for the structure of the lunar interior to about a 250-km depth is proposed. It is suggested that this region is composed of plagioclase-bearing rocks, and that the 65-km seismic discontinuity represents the appearance of garnet. A variety of rock types mainly composed of plagioclase, pyroxene, olivine and garnet is envisioned, with at least half of the outer 250 km of the moon made of plagioclase, which dominates the electrical conductivity. This model agrees with recent petrological and electrical conductivity results and does not violate velocity-depth profiles obtained from elastic-wave studies of lunar and terrestrial materials. (U.S.)

  3. 41 CFR 60-250.64 - Show cause notices.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Show cause notices. 60... VETERANS General Enforcement and Complaint Procedures § 60-250.64 Show cause notices. When the Deputy Assistant Secretary has reasonable cause to believe that the contractor has violated the Act or this...

  4. 30 CFR 250.1202 - Liquid hydrocarbon measurement.

    Science.gov (United States)

    2010-07-01

    ... applications Creation of new facility measurement points (FMPs); Association of leases or units with existing... the API MPMS as incorporated by reference in 30 CFR 250.198, when obtaining net standard volume and... displacement (pipe) prover, master meter, or tank prover; (iii) A proportional-to-flow sampling device...

  5. 5 CFR 250.202 - Office of Personnel Management responsibilities.

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.202 Office of Personnel... Governmentwide leadership and direction in the strategic management of the Federal workforce. (b) To execute this... to which human capital management strategies are integrated into agency strategic plans...

  6. 5 CFR 250.201 - Coverage and purpose.

    Science.gov (United States)

    2010-01-01

    ....201 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.201 Coverage and purpose. The Chief Human... the strategic management of the Federal civil service, and pursuant to 5 U.S.C. 1103, OPM...

  7. The Varian MAT-250 mass spectrometer. Steady isotopes laboratory

    International Nuclear Information System (INIS)

    This work treats over the performance and applications of the Varian Mat-250 mass spectrometer which is in the environmental isotope laboratory. It can be applied over topics such as: ions formation, acceleration and collimation, ions separation, ions detection, data transformation, sampling, δ notation. (Author)

  8. 30 CFR 250.611 - Traveling-block safety device.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Traveling-block safety device. 250.611 Section... Traveling-block safety device. After May 31, 1989, all units being used for well-workover operations which have both a traveling block and a crown block shall be equipped with a safety device which is...

  9. 30 CFR 250.511 - Traveling-block safety device.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Traveling-block safety device. 250.511 Section... Traveling-block safety device. All units being used for well-completion operations that have both a traveling block and a crown block must be equipped with a safety device that is designed to prevent...

  10. 30 CFR 250.102 - What does this part do?

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Authority and Definition of Terms § 250.102 What does this... CFR 254. (11) Oil and gas well-completion operations E. (12) Oil and gas well-workover operations...

  11. 9 CFR 2.50 - Time and method of identification.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Time and method of identification. 2... AGRICULTURE ANIMAL WELFARE REGULATIONS Identification of Animals § 2.50 Time and method of identification. (a... by any dealer or exhibitor shall be identified by the dealer or exhibitor at the time of delivery...

  12. 41 CFR 60-250.23 - Medical examinations and inquiries.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Medical examinations and... PROTECTED VETERANS Discrimination Prohibited § 60-250.23 Medical examinations and inquiries. (a) Prohibited medical examinations or inquiries. Except as stated in paragraphs (b) and (c) of this section, it...

  13. 38 CFR 3.250 - Dependency of parents; compensation.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Dependency of parents....250 Dependency of parents; compensation. (a) Income—(1) Conclusive dependency. Dependency of a parent... not exceed: (i) $400 for a mother or father not living together; (ii) $660 for a mother and father,...

  14. The Varian MAT-250 mass spectrometer. Steady isotopes laboratory; Espectrometro de masas Varian MAT-250. Laboratorio de isotopos estables

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez M, V.; Tavera D, M.L. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    1997-07-01

    This work treats over the performance and applications of the Varian Mat-250 mass spectrometer which is in the environmental isotope laboratory. It can be applied over topics such as: ions formation, acceleration and collimation, ions separation, ions detection, data transformation, sampling, {delta} notation. (Author)

  15. Tourette syndrome: clinical and psychological aspects of 250 cases.

    OpenAIRE

    Comings, D E; Comings, B G

    1985-01-01

    Tourette syndrome is a common hereditary neuropsychiatric disorder consisting of multiple tics and vocal noises. We summarize here clinical aspects of 250 consecutive cases seen over a period of 3 years. The sex ratio was four males to one female, and the mean age of onset was 6.9 years. Only 10% were Jewish, indicating that it is not more prevalent in Ashkenazi Jews. Only 33% had compulsive swearing (coprolalia), indicating that this is not necessary for the diagnosis. The most frequent init...

  16. Superfund GIS - 1:250,000 Geology of Tennessee

    Science.gov (United States)

    Greene, D.C.; Wolfe, W.J.

    2000-01-01

    This data set is a digital representation of the printed 1:250,000 geologic maps from the Tennessee Department of Environment and Conservation, Division of Geology. The coverage was designed primarily to provide a more detailed geologic base than the 1:2,500,000 King and Beikman (1974). 1:24,000 scale coverage of the state is available for about 40 percent of the state. Formation names and geologic unit codes used in the coverage are from the Tennessee Division of Geology published maps and may not conform to USGS nomenclature. The Tennessee Division of Geology can be contacted at (615) 532-1500

  17. 20 CFR 1010.250 - Can priority of service be waived?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Can priority of service be waived? 1010.250 Section 1010.250 Employees' Benefits OFFICE OF THE ASSISTANT SECRETARY FOR VETERANS' EMPLOYMENT AND... Priority of Service § 1010.250 Can priority of service be waived? No, priority of service cannot be waived....

  18. 30 CFR 250.1010 - General requirements for pipeline right-of-way holders.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false General requirements for pipeline right-of-way holders. 250.1010 Section 250.1010 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Rights-of-Way § 250.1010 General requirements for pipeline right-of-way holders. An applicant,...

  19. 7 CFR 250.52 - Storage and inventory management of donated foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Storage and inventory management of donated foods. 250... Donated Foods in Contracts With Food Service Management Companies § 250.52 Storage and inventory... general requirements in § 250.14(b) for the storage and inventory management of donated foods. (b)...

  20. 21 CFR 250.101 - Amphetamine and methamphetamine inhalers regarded as prescription drugs.

    Science.gov (United States)

    2010-04-01

    ... as prescription drugs. 250.101 Section 250.101 Food and Drugs FOOD AND DRUG ADMINISTRATION... DRUGS New Drug or Prescription Status of Specific Drugs § 250.101 Amphetamine and methamphetamine... should not be freely available to the public through over-the-counter sale. From complaints by...

  1. 17 CFR 250.7 - Companies deemed not to be electric or gas utility companies.

    Science.gov (United States)

    2010-04-01

    ... electric or gas utility companies. 250.7 Section 250.7 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General Exemptions § 250.7 Companies deemed not to be electric or gas utility companies....

  2. 40 CFR 421.250 - Applicability: Description of the primary precious metals and mercury subcategory.

    Science.gov (United States)

    2010-07-01

    ... primary precious metals and mercury subcategory. 421.250 Section 421.250 Protection of Environment... POINT SOURCE CATEGORY Primary Precious Metals and Mercury Subcategory § 421.250 Applicability: Description of the primary precious metals and mercury subcategory. The provisions of this subpart...

  3. 30 CFR 250.1012 - Required payments for pipeline right-of-way holders.

    Science.gov (United States)

    2010-07-01

    ... in 30 CFR 218.54. If you fail to make a payment that is late after written notice from MMS, MMS may initiate cancellation of the right-of-use grant and easement under 30 CFR 250.1013. ... holders. 250.1012 Section 250.1012 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF...

  4. 30 CFR 250.1011 - Bond requirements for pipeline right-of-way holders.

    Science.gov (United States)

    2010-07-01

    ... holders. 250.1011 Section 250.1011 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Rights-of-Way § 250.1011 Bond requirements for pipeline right-of-way holders. (a) When you apply for, or are the holder of, a right-of-way, you must: (1) Provide and maintain a $300,000 bond (in addition...

  5. 30 CFR 250.411 - What information must I submit with my application?

    Science.gov (United States)

    2010-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Applying for A Permit to Drill § 250.411 What information must I submit with my application? In addition to... proposed well § 250.412 (b) Design criteria used for the proposed well § 250.413 (c) Drilling...

  6. 17 CFR 250.60 - Meaning of word “authorization”.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Meaning of word... Reorganizations § 250.60 Meaning of word “authorization”. The word “authorization”, as used in §§ 250.60 to 250.64, includes “any proxy, consent, authorization, power of attorney, deposit, or dissent”, as those words...

  7. 20 CFR 416.250 - Experimental, pilot, and demonstration projects in the SSI program.

    Science.gov (United States)

    2010-04-01

    ... projects in the SSI program. 416.250 Section 416.250 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... Because of Essential Persons § 416.250 Experimental, pilot, and demonstration projects in the SSI program... administration of the SSI program. These projects will test the advantages of altering certain...

  8. 30 CFR 250.1004 - Safety equipment requirements for DOI pipelines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Safety equipment requirements for DOI pipelines. 250.1004 Section 250.1004 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...-Way § 250.1004 Safety equipment requirements for DOI pipelines. (a) The lessee shall ensure the...

  9. 30 CFR 250.1003 - Installation, testing, and repair requirements for DOI pipelines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Installation, testing, and repair requirements for DOI pipelines. 250.1003 Section 250.1003 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... and Pipeline Rights-of-Way § 250.1003 Installation, testing, and repair requirements for DOI...

  10. 30 CFR 250.516 - Blowout preventer system tests, inspections, and maintenance.

    Science.gov (United States)

    2010-07-01

    ... Well-Completion Operations § 250.516 Blowout preventer system tests, inspections, and maintenance. (a... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Blowout preventer system tests, inspections, and maintenance. 250.516 Section 250.516 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT...

  11. 30 CFR 250.109 - What documents must I prepare and maintain related to welding?

    Science.gov (United States)

    2010-07-01

    ... related to welding? 250.109 Section 250.109 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF... Performance Standards § 250.109 What documents must I prepare and maintain related to welding? (a) You must submit a Welding Plan to the District Manager before you begin drilling or production activities on...

  12. 30 CFR 250.104 - How may I appeal a decision made under MMS regulations?

    Science.gov (United States)

    2010-07-01

    ... regulations? 250.104 Section 250.104 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Authority and Definition... decisions issued under MMS regulations in 30 CFR parts 250 to 282, follow the procedures in 30 CFR part 290....

  13. 30 CFR 250.226 - What Coastal Zone Management Act (CZMA) information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What Coastal Zone Management Act (CZMA) information must accompany the EP? 250.226 Section 250.226 Mineral Resources MINERALS MANAGEMENT SERVICE... and Information Contents of Exploration Plans (ep) § 250.226 What Coastal Zone Management Act...

  14. Bayesian demography 250 years after Bayes.

    Science.gov (United States)

    Bijak, Jakub; Bryant, John

    2016-01-01

    Bayesian statistics offers an alternative to classical (frequentist) statistics. It is distinguished by its use of probability distributions to describe uncertain quantities, which leads to elegant solutions to many difficult statistical problems. Although Bayesian demography, like Bayesian statistics more generally, is around 250 years old, only recently has it begun to flourish. The aim of this paper is to review the achievements of Bayesian demography, address some misconceptions, and make the case for wider use of Bayesian methods in population studies. We focus on three applications: demographic forecasts, limited data, and highly structured or complex models. The key advantages of Bayesian methods are the ability to integrate information from multiple sources and to describe uncertainty coherently. Bayesian methods also allow for including additional (prior) information next to the data sample. As such, Bayesian approaches are complementary to many traditional methods, which can be productively re-expressed in Bayesian terms. PMID:26902889

  15. Corrosion of titanium in phosphoric acid at 250

    Institute of Scientific and Technical Information of China (English)

    LU Jian-shu

    2009-01-01

    Corrosion studies of a commercially pure titanium in phosphoric acid solutions at 250 ℃ were carried out by immersion test in an autoclave. At lower phosphoric acid concentration (0.1 mol/L), the corrosion was mild. At higher phosphoric concentration (1.0 mol/L) corrosion, a 25 μm-thick white corrosion products layer was formed on the samples after 24 h immersion. XRD analysis shows that the white layer consists mainly of titanium oxide phosphate hydrate (π-Ti2O(PO4)2·2H2O). The corrosion product shows the morphology of fiber bundles. A thermodynamic analysis of the formation of the corrosion product is presented.

  16. Standard potential of sodium amalgam at 250C

    International Nuclear Information System (INIS)

    From a set of critically selected literary data on the emf's of concentration cells consisting of sodium metal and sodium amalgam in a sodium salt non-aqueous electrolyte a value of E0sub(Na(Hg)/Na+) = -1.95584 V was calculated for the standard equilibrium potential of diluted liquid sodium amalgam at 250C. The standard state of the amalgam was derived from an amalgam at infinite dilution where fsub(Na)→ 1.0 for xsub(Na)→ 0. The activity coefficient of sodium in the amalgam at an arbitrary composition, corresponding to this standard state, is obtained from the expression 1g fsub(Na(Hg)) = 16.393 xsub(Na). (author)

  17. Flood basalt volcanism during the past 250 million years

    Science.gov (United States)

    Rampino, Michael R.; Stothers, Richard B.

    1988-01-01

    A chronology of the initiation dates of major continental flood basalt volcanism is established from published potassium-argon (K-Ar) and argon-argon (Ar-Ar) ages of basaltic rocks and related basic intrusions. The dating is therefore independent of the biostratigraphic and paleomagnetic time scales. Estimated errors of the initiation dates of the volcanic episodes determined from the distributions of the radiometric ages are, approximately, + or - 4 percent. There were 11 distinct episodes during the past 250 million years. Sometimes appearing in pairs, the episodes have occurred quasi-periodically with a mean cycle time of 32 + or - 1 (estimated error of the mean) million years. The initiation dates of the episodes are close to the estimated dates of mass extinctions of marine organisms. Showers of impacting comets may be the cause.

  18. Remote (250 km Fiber Bragg Grating Multiplexing System

    Directory of Open Access Journals (Sweden)

    Manuel Lopez-Amo

    2011-09-01

    Full Text Available We propose and demonstrate two ultra-long range fiber Bragg grating (FBG sensor interrogation systems. In the first approach four FBGs are located 200 km from the monitoring station and a signal to noise ratio of 20 dB is obtained. The second improved version is able to detect the four multiplexed FBGs placed 250 km away, offering a signal to noise ratio of 6–8 dB. Consequently, this last system represents the longest range FBG sensor system reported so far that includes fiber sensor multiplexing capability. Both simple systems are based on a wavelength swept laser to scan the reflection spectra of the FBGs, and they are composed by two identical-lengths optical paths: the first one intended to launch the amplified laser signal by means of Raman amplification and the other one is employed to guide the reflection signal to the reception system.

  19. Bayesian demography 250 years after Bayes.

    Science.gov (United States)

    Bijak, Jakub; Bryant, John

    2016-01-01

    Bayesian statistics offers an alternative to classical (frequentist) statistics. It is distinguished by its use of probability distributions to describe uncertain quantities, which leads to elegant solutions to many difficult statistical problems. Although Bayesian demography, like Bayesian statistics more generally, is around 250 years old, only recently has it begun to flourish. The aim of this paper is to review the achievements of Bayesian demography, address some misconceptions, and make the case for wider use of Bayesian methods in population studies. We focus on three applications: demographic forecasts, limited data, and highly structured or complex models. The key advantages of Bayesian methods are the ability to integrate information from multiple sources and to describe uncertainty coherently. Bayesian methods also allow for including additional (prior) information next to the data sample. As such, Bayesian approaches are complementary to many traditional methods, which can be productively re-expressed in Bayesian terms.

  20. Shock compression response of forsterite above 250 GPa.

    Science.gov (United States)

    Sekine, Toshimori; Ozaki, Norimasa; Miyanishi, Kohei; Asaumi, Yuto; Kimura, Tomoaki; Albertazzi, Bruno; Sato, Yuya; Sakawa, Youichi; Sano, Takayoshi; Sugita, Seiji; Matsui, Takafumi; Kodama, Ryosuke

    2016-08-01

    Forsterite (Mg2SiO4) is one of the major planetary materials, and its behavior under extreme conditions is important to understand the interior structure of large planets, such as super-Earths, and large-scale planetary impact events. Previous shock compression measurements of forsterite indicate that it may melt below 200 GPa, but these measurements did not go beyond 200 GPa. We report the shock response of forsterite above ~250 GPa, obtained using the laser shock wave technique. We simultaneously measured the Hugoniot and temperature of shocked forsterite and interpreted the results to suggest the following: (i) incongruent crystallization of MgO at 271 to 285 GPa, (ii) phase transition of MgO at 285 to 344 GPa, and (iii) remelting above ~470 to 500 GPa. These exothermic and endothermic reactions are seen to occur under extreme conditions of pressure and temperature. They indicate complex structural and chemical changes in the system MgO-SiO2 at extreme pressures and temperatures and will affect the way we understand the interior processes of large rocky planets as well as material transformation by impacts in the formation of planetary systems. PMID:27493993

  1. Grammaire pour adolescents 250 exercices : niveau débutant

    CERN Document Server

    Bié, Nathalie

    2005-01-01

    Ce nouveau livre d'exercices de grammaire, de la collection Le Nouvel Entraînez-vous, s'adresse à un public d'adolescents débutants et faux débutants en français langue étrangère. L'ouvrage propose 250 exercices de compréhension et de mémorisation à travers des activités de déduction et de réemploi des notions grammaticales étudiées. Le contenu des exercices est organisé autour de contextes langagiers proches de la réalité des adolescents afin de placer la communication au cœur de l'apprentissage. L'introduction des contenus grammaticaux suit la même progression que les méthodes usuelles. Chaque chapitre débute par une séquence Rappel permettant à l'apprenant de revoir rapidement les règles grammaticales développées dans les exercices. Chaque exercice est introduit par une consigne brève et concise accompagnée d'un exemple. L'ouvrage a été conçu en tenant compte des centres d'intérêts des adolescents et propose de nombreuses illustrations intégrées aux exercices. A la fin d...

  2. The Undergraduate ALFALFA Team: Outcomes for Over 250 Undergraduate Participants

    Science.gov (United States)

    Troischt, Parker; Koopmann, Rebecca A.; Haynes, Martha P.; ALFALFA Team

    2016-01-01

    The NSF-sponsored Undergraduate ALFALFA (Arecibo Legacy Fast ALFA) Team (UAT) is a consortium of 19 institutions founded to promote undergraduate research and faculty development within the extragalactic ALFALFA HI blind survey project and follow-up programs. In this talk we present outcomes for the more than 250 undergraduate students who have who have participated in the program during the 8 years of funding. 40% of these students have been women and members of underrepresented groups. To date 148 undergraduate students have attended annual workshops at Arecibo Observatory, interacting with faculty, graduate students, their peers, and Arecibo staff in lectures, group activities, tours, and observing runs. Team faculty have supervised 159 summer research projects and 120 academic year (e.g., senior thesis) projects. 68 students have traveled to Arecibo Observatory for observing runs and 55 have presented their results at national meetings such as the AAS. Through participation in the UAT, students are made aware of career paths they may not have previously considered. More than 90% of alumni are attending graduate school and/or pursuing a career in STEM. 42% of those pursuing graduate degrees in Physics or Astronomy are women. This work has been supported by NSF grants AST-0724918/0902211, AST-075267/0903394, AST-0725380, and AST-1211005

  3. Structural testing of the North Wind 250 composite rotor joint

    Science.gov (United States)

    Musial, W.; Link, H.; Coleman, C.

    1994-05-01

    The North Wind 250 wind turbine is under development at Northern Power Systems (NPS) in Moretown, VT. The turbine uses a unique, flow-through, teetered-rotor design. This design eliminates structural discontinuities at the blade/hub interface by fabricating the rotor as one continuous structural element. To accomplish this, the two blade spars are joined at the center of the rotor using a proprietary bonding technique. Fatigue tests were conducted on the full-scale rotor joint at the National Renewable Energy Laboratory (NREL). Subsequent tests are now underway to test the full-scale rotor and hub assembly to verify the design assumptions. The test articles were mounted in dedicated test fixtures. For the joint test, a constant moment was generated across the joint and parent material. Hydraulic actuators applied sinusoidal loading to the test article at levels equivalent to 90% of the extreme wind load for over one million cycles. When the loading was increased to 112% of the extreme wind load, the joint failed by buckling. Strain levels were monitored at 14 locations inside and outside of the blade joint during the test. The tests were used to qualify this critical element of the rotor for field testing and to provide information needed to improve the structural design of the joint.

  4. A family of doctors over 250 years: innovation and controversy.

    Science.gov (United States)

    Watkins, Peter J

    2011-05-01

    A family of Watkins doctors originating in the Northamptonshire town of Towcester included 13 doctors in seven generations during 250 years. In each generation there were between one and four doctors. Three doctors involved themselves actively in innovative yet controversial practises, described in their own writings and publications. Timothy Watkins' (1755-1834) own handwritten lecture notes describe the problems affecting an 18th-century man-midwife, while his accounts book provides insights into his lifestyle. The concept of the waterborne spread of cholera during the 1854 epidemic in Towcester is described by Robert Webb Watkins (1822-1901) during the same year as the observations made by John Snow (1813-58). John Webb Watkins (1833-1903) in his MD thesis (1856) describes his use of chloroform in labour in Towcester during the early 1850s, followed by self-experimentation with chloroform administered to him between 40 and 50 times by Sir James Young Simpson (1811-70) in Edinburgh. Descriptions of the two 19th-century general practitioners offer insights into the exemplary extent of their civic involvement in all walks of local community life, and of their family ties. PMID:21558531

  5. Shock compression response of forsterite above 250 GPa

    Science.gov (United States)

    Sekine, Toshimori; Ozaki, Norimasa; Miyanishi, Kohei; Asaumi, Yuto; Kimura, Tomoaki; Albertazzi, Bruno; Sato, Yuya; Sakawa, Youichi; Sano, Takayoshi; Sugita, Seiji; Matsui, Takafumi; Kodama, Ryosuke

    2016-01-01

    Forsterite (Mg2SiO4) is one of the major planetary materials, and its behavior under extreme conditions is important to understand the interior structure of large planets, such as super-Earths, and large-scale planetary impact events. Previous shock compression measurements of forsterite indicate that it may melt below 200 GPa, but these measurements did not go beyond 200 GPa. We report the shock response of forsterite above ~250 GPa, obtained using the laser shock wave technique. We simultaneously measured the Hugoniot and temperature of shocked forsterite and interpreted the results to suggest the following: (i) incongruent crystallization of MgO at 271 to 285 GPa, (ii) phase transition of MgO at 285 to 344 GPa, and (iii) remelting above ~470 to 500 GPa. These exothermic and endothermic reactions are seen to occur under extreme conditions of pressure and temperature. They indicate complex structural and chemical changes in the system MgO-SiO2 at extreme pressures and temperatures and will affect the way we understand the interior processes of large rocky planets as well as material transformation by impacts in the formation of planetary systems. PMID:27493993

  6. Bionics by examples 250 scenarios from classical to modern times

    CERN Document Server

    Nachtigall, Werner

    2015-01-01

    Bionics means learning from the nature for the development of technology. The science of "bionics" itself is classified into several sections, from materials and structures over procedures and processes until evolution and optimization. Not all these areas, or only a few, are really known in the public and also in scientific literature. This includes the Lotus-effect, converted to the contamination-reduction of fassades and the shark-shed-effect, converted to the  resistance-reduction of airplanes. However, there are hundreds of highly interesting examples that contain the transformation of principles of the nature into technology. From the large number of these examples, 250 were selected for the present book according to "prehistory", "early-history", "classic" and "modern time". Most examples are new. Every example includes a printed page in a homogeneous arrangement. The examples from the field "modern time" are joint in blocks corresponding to the sub-disciplines of bionics.

  7. Evaluation of some aspects of the VITROS 250 Bio-Chemistry analyzer%VITROS 250全自动干化学分析仪的评价

    Institute of Scientific and Technical Information of China (English)

    林有东; 蔡鹏威

    2006-01-01

    目的 评价美国强生VITROS 250全自动干化学分析仪器.方法 运用相关统计学方法对VITROS 250全自动干化学分析仪的精密度、相关性、抗胆红素干扰方面进行分析.结果 VITROS 250全自动干化学分析仪精密度高,回收率高,相关性好,抗干扰能力强.结论 VITROS 250全自动干化学分析仪适用于临床实验诊断中心(检验科)急诊化验室生化项目的检测.

  8. Study of solar features causing GMSs with 250 < < 400

    Indian Academy of Sciences (India)

    Santosh Kumar; Mahendra Pratap Yadav

    2003-07-01

    The effect of solar features on geospheric conditions leading to geomagnetic storms (GMSs) with planetary index, p ≥ 20 and the range of horizontal component of the Earth’s magnetic field such that 250 < < 400 has been investigated using interplanetary magnetic field (IMF), solar wind plasma (SWP) and solar geophysical data (SGD) during the period 1978–99. Statistically, it is observed that maximum number of GMSs have occurred during the maximum solar activity years of 21st and 22nd solar cycles. A peculiar result has been observed during the years 1982, 1994 when sunspot numbers (SSNs) decrease very rapidly while numbers of GMSs increase. No distinct association between yearly occurrence of disturbed days and SSNs is observed. Maximum number of disturbed days have occurred during spring and rainy seasons showing a seasonal variation of disturbed days. No significant correlation between magnitude (intensity) of GMSs and importance of , X-ray solar flares has been observed. Maximum number of GMSs is associated with solar flares of lower importance, i.e., SF during the period 1978–93. , X-ray solar flares occurred within lower helio-latitudes, i.e., (0–30)°N to (0–30)°S are associated with GMSs. No , X-ray solar flares have occurred beyond 40°N or 40°S in association with GMSs. In helio-latitude range (10–40)°N to (10–40)°S, the 89.5% concentration of active prominences and disappearing filaments (APDFs) are associated with GMSs. Maximum number of GMSs are associated with solar flares. Coronal mass ejections (CMEs) are related with eruptive prominences, solar flares, type IV radio burst and they occur at low helio-latitude. It is observed that CMEs related GMS events are not always associated with high speed solar wind streams (HSSWSs). In many individual events, the travel time between the explosion on the Sun and maximum activity lies between 58 and 118 h causing GMSs at the Earth.

  9. Hydrological variability in northern Levant over the past 250 ka

    Directory of Open Access Journals (Sweden)

    F. Gasse

    2011-05-01

    Full Text Available The Levant features sharp climatic gradients from North to South and from West to East resulting in a large environmental diversity. The lack of long-term record from the northern Levant limits our understanding of the regional response to glacial-interglacial boundary conditions in this key area. The 250 ka paleoenvironmental reconstruction presented here is a first step to fill this geographical gap.

    The record comes from a 36 m lacustrine-palustrine sequence cored in the small intra-mountainous karstic basin of Yammoûneh (northern Lebanon. The paper combines times series of sediment properties, paleovegetation, and carbonate oxygen isotopes, to yield a comprehensive view of paleohydrologic-paleoclimatic fluctuations in the basin over the two last glacial-interglacial cycles. Efficient moisture was higher than today during interglacial peaks around 240, 215–220, ~130–120 ka and 11–9 ka (although under different Precipitation minus Evaporation balance. Moderate wetting events took place around 170, 150, 105–100, 85–75, 60–55 and 35 ka. The penultimate glacial period was generally wetter than the last glacial stage. Local aridity culminated from the LGM to 15 ka, possibly linked to water storage as ice in the surrounding highlands. An overall decrease in local water availability is observed from the profile base to top. Fluctuations in available water seem to be primarily governed by changes in local summer insolation controlled by the orbital eccentricity modulated by the precession cycle, and by changes in precipitation and temperature seasonality.

    Our record is roughly consistent with long-term climatic fluctuations in northeastern Mediterranean lands, except during the penultimate glacial phase. It shares some features with speleothem records of western Israel. Conversely, after 130 ka, it is clearly out of phase with hydrological changes in the Dead Sea basin. Potential causes of these spatial heterogeneities

  10. 30 CFR 250.192 - What reports and statistics must I submit relating to a hurricane, earthquake, or other natural...

    Science.gov (United States)

    2010-07-01

    ... submitting your statistics by fax or e-mail, you may submit them electronically in accordance with 30 CFR 250... electronically in accordance with 30 CFR 250.186(a)(3). In the report, you must: (i) Name the items damaged (e.g... relating to a hurricane, earthquake, or other natural occurrence? 250.192 Section 250.192 Mineral...

  11. 41 CFR 60-250.70 - Disputed matters related to compliance with the Act.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Disputed matters related to compliance with the Act. 60-250.70 Section 60-250.70 Public Contracts and Property Management... SEPARATED VETERANS, AND OTHER PROTECTED VETERANS General Enforcement and Complaint Procedures §...

  12. 7 CFR 250.59 - Storage and inventory management of donated foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Storage and inventory management of donated foods. 250... National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.59 Storage and inventory management of donated foods. (a) General requirements. Distributing agencies, subdistributing agencies,...

  13. 30 CFR 250.1506 - How often must I train my employees?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How often must I train my employees? 250.1506... Training § 250.1506 How often must I train my employees? You determine the frequency of the training you provide your employees. You must do all of the following: (a) Provide periodic training to ensure...

  14. 30 CFR 250.1505 - Where may I get training for my employees?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Where may I get training for my employees? 250... Safety Training § 250.1505 Where may I get training for my employees? You may get training from any source that meets the requirements of your training plan....

  15. 30 CFR 250.410 - How do I obtain approval to drill a well?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I obtain approval to drill a well? 250... OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Applying for A Permit to Drill § 250.410 How do I obtain approval to drill a well? You must obtain...

  16. 12 CFR 250.403 - Service of member bank and real estate investment company.

    Science.gov (United States)

    2010-01-01

    ... Board took the position that a closed-end investment company which was in process of organization and... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Service of member bank and real estate investment company. 250.403 Section 250.403 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD...

  17. 30 CFR 250.444 - What are the choke manifold requirements?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the choke manifold requirements? 250... Blowout Preventer (bop) System Requirements § 250.444 What are the choke manifold requirements? (a) Your BOP system must include a choke manifold that is suitable for the anticipated surface...

  18. 45 CFR 286.250 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What definitions apply to this subpart? 286.250 Section 286.250 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL TANF PROVISIONS Data Collection...

  19. 41 CFR 60-250.25 - Health insurance, life insurance and other benefit plans.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Health insurance, life insurance and other benefit plans. 60-250.25 Section 60-250.25 Public Contracts and Property Management..., life insurance and other benefit plans. (a) An insurer, hospital, or medical service company,...

  20. 30 CFR 250.455 - What are the general requirements for a drilling fluid program?

    Science.gov (United States)

    2010-07-01

    ... well control. This program must address drilling fluid safe practices, testing and monitoring equipment... drilling fluid program? 250.455 Section 250.455 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil...

  1. 30 CFR 250.424 - What are the requirements for prolonged drilling operations?

    Science.gov (United States)

    2010-07-01

    ... the prolonged operations on continued drilling operations and the life of the well. At a minimum, you... drilling operations? 250.424 Section 250.424 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and...

  2. 30 CFR 250.1160 - When may I flare or vent gas?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may I flare or vent gas? 250.1160 Section..., Venting, and Burning Hydrocarbons § 250.1160 When may I flare or vent gas? (a) You must request and receive approval from the Regional Supervisor to flare or vent natural gas at your facility, except in...

  3. 12 CFR 250.400 - Service of open-end investment company.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Service of open-end investment company. 250.400 Section 250.400 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL....400 Service of open-end investment company. An open-end investment company is defined in section...

  4. 41 CFR Appendix A to Part 61 - 250-Federal Contractor Veterans' Employment Report VETS-100

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 250-Federal Contractor Veterans' Employment Report VETS-100 A Appendix A to Part 61 Public Contracts and Property Management Other... Appendix A to Part 61-250—Federal Contractor Veterans' Employment Report VETS-100 ER05NO08.000...

  5. 30 CFR 250.908 - What are the minimum structural fatigue design requirements?

    Science.gov (United States)

    2010-07-01

    ... Platform Approval Program § 250.908 What are the minimum structural fatigue design requirements? (a) API RP 2A-WSD, Recommended Practice for Planning, Designing and Constructing Fixed Offshore Platforms (incorporated by reference as specified in 30 CFR 250.198), requires that the design fatigue life of each...

  6. 30 CFR 250.1629 - Additional production and fuel gas system requirements.

    Science.gov (United States)

    2010-07-01

    ... systems must conform to subsection 5.2, Fire Water Systems, of API RP 14G, Recommended Practice for Fire... as specified in 30 CFR 250.198). Pressure and fired vessels must have maintenance inspection, rating.../ASME Boiler and Pressure Vessel Code (incorporated by reference as specified in 30 CFR 250.198)....

  7. 48 CFR 250.104-3 - Special procedures for unusually hazardous or nuclear risks.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Special procedures for unusually hazardous or nuclear risks. 250.104-3 Section 250.104-3 Federal Acquisition Regulations System... unusually hazardous or nuclear risks....

  8. 40 CFR 436.250 - Applicability; description of the jade subcategory.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Applicability; description of the jade subcategory. 436.250 Section 436.250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Jade...

  9. 30 CFR 250.1752 - How do I remove a pipeline?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I remove a pipeline? 250.1752 Section... GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Decommissioning Activities Pipeline Decommissioning § 250.1752 How do I remove a pipeline? Before removing a pipeline, you must: (a) Submit a...

  10. 21 CFR 107.250 - Termination of an infant formula recall.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Termination of an infant formula recall. 107.250... (CONTINUED) FOOD FOR HUMAN CONSUMPTION INFANT FORMULA Infant Formula Recalls § 107.250 Termination of an infant formula recall. The recalling firm may submit a recommendation for termination of the recall...

  11. 32 CFR 250.7 - Pertinent portions of Export Administration Regulations (EAR).

    Science.gov (United States)

    2010-07-01

    ... technical data under the authority of this part. Export Administration Regulations 15 CFR 379.3 General... accordance with the regulations of the Patent and Trademark Office 37 CFR part 5. See § 370.10(j).) ... Regulations (EAR). 250.7 Section 250.7 National Defense Department of Defense (Continued) OFFICE OF...

  12. Soil property maps of Africa at 250 m resolution

    Science.gov (United States)

    Kempen, Bas; Hengl, Tomislav; Heuvelink, Gerard B. M.; Leenaars, Johan G. B.; Walsh, Markus G.; MacMillan, Robert A.; Mendes de Jesus, Jorge S.; Shepherd, Keith; Sila, Andrew; Desta, Lulseged T.; Tondoh, Jérôme E.

    2015-04-01

    Vast areas of arable land in sub-Saharan Africa suffer from low soil fertility and physical soil constraints, and significant amounts of nutrients are lost yearly due to unsustainable soil management practices. At the same time it is expected that agriculture in Africa must intensify to meet the growing demand for food and fiber the next decades. Protection and sustainable management of Africa's soil resources is crucial to achieve this. In this context, comprehensive, accurate and up-to-date soil information is an essential input to any agricultural or environmental management or policy and decision-making model. In Africa, detailed soil information has been fragmented and limited to specific zones of interest for decades. To help bridge the soil information gap in Africa, the Africa Soil Information Service (AfSIS) project was established in 2008. AfSIS builds on recent advances in digital soil mapping, infrared spectroscopy, remote sensing, (geo)statistics, and integrated soil fertility management to improve the way soils are evaluated, mapped, and monitored. Over the period 2008-2014, the AfSIS project has compiled two soil profile data sets (about 28,000 unique locations): the Africa Soil Profiles (legacy) database and the AfSIS Sentinel Site (new soil samples) database -- the two data sets represent the most comprehensive soil sample database of the African continent to date. In addition a large set of high-resolution environmental data layers (covariates) was assembled. The point data were used in the AfSIS project to generate a set of maps of key soil properties for the African continent at 250 m spatial resolution: sand, silt and clay fractions, bulk density, organic carbon, total nitrogen, pH, cation-exchange capacity, exchangeable bases (Ca, K, Mg, Na), exchangeable acidity, and Al content. These properties were mapped for six depth intervals up to 2 m: 0-5 cm, 5-15 cm, 15-30 cm, 30-60 cm, 60-100 cm, and 100-200 cm. Random forests modelling was used to

  13. The multiplicity of 250-$\\mu$m Herschel sources in the COSMOS field

    CERN Document Server

    Scudder, Jillian M; Hurley, Peter D; Griffin, Matt; Sargent, Mark T; Scott, Douglas; Wang, Lingyu; Wardlow, Julie L

    2016-01-01

    We investigate the multiplicity of extragalactic sources detected by the Herschel Space Observatory in the COSMOS field. Using 3.6- and 24-$\\mu$m catalogues, in conjunction with 250-$\\mu$m data from Herschel, we seek to determine if a significant fraction of Herschel sources are composed of multiple components emitting at 250 $\\mu$m. We use the XID+ code, using Bayesian inference methods to produce probability distributions of the possible contributions to the observed 250-$\\mu$m flux for each potential component. The fraction of Herschel flux assigned to the brightest component is highest for sources with total 250-$\\mu$m fluxes < 45 mJy; however, the flux in the brightest component is still highest in the brightest Herschel sources. The faintest 250-$\\mu$m sources (30-45 mJy) have the majority of their flux assigned to a single bright component; the second brightest component is typically significantly weaker, and contains the remainder of the 250-$\\mu$m source flux. At the highest 250-$\\mu$m fluxes (45-...

  14. Pulverização em CDA 250 herbicida pendimethalin na cultura do arroz de sequeiro Application of pendimethalin with cda 250 spfayer for upland rice

    Directory of Open Access Journals (Sweden)

    T. Matuo

    1984-01-01

    Full Text Available Foi estudada a viabilidade de utilização da pulverização CDA 25C, na aplicação do herbicida em pré-emergência na cultura do arroz de sequeiro. O herbicida empregado foi o pendimethalin nas doses de 0,0; 1,5; 2,0; 2,5 e 3,0 litro s/ha da formulação comercial a 50%. A pulverização convencional foi efetuada com bicos 11003 com consumo de 200 litros de calda per hectare. O processo CDA 250 foi aplicado por meio de bico rotativo (Micromax com dois níveis de consumo de calda : 50 1/ha e 27 1/ha. Os resultados mostraram que: a - o método CDA 250 proporciona controle dc mato e produtividade de arroz equivalentes ao método convencional; b para o bico Micromax, a aplicação da formulação comercial de pendimethalin a 50% com vazão de 0,48 1/min./bico, a distância entre bicos deve ser de 1,75 m e para a vazão de 0,96 1/min./bloco, essa distancia deve ser de 1,90 m; c- a aplicação do pendimethalin 50% C.E. pelo processo CDA 250, empregando 27 litros de calda por hectare foi o processo mais interessante por oferecer vantagens logísticas apreciáveis.The feasibility of pre-emergenge herbicide application for upland rice by CDA 250 spray method was studied. The herbicide used was pen dimethalin at 0,0; 1,5; 2,0; 2,5 and 3,0 1/ha of comercial 50% E.C. formulation. Conventional spraying was carried out using 110C3 flat fan nozzles applying 200 1/ha of spray volume CDA250 was applied by rotary atomizers (Micromax spraying twc volume rates: 50 1/ha and 27 1/ha. The results pointed out that: a- CDA 250 spray method was equivalent to the conventional spray method in the control of weeds and crop yield; b - for Micromax nozzles applying commercial 50 E.C. formulation of pendimethalin at 0,48 /min of nozzle feed rate, the distance between nozzles should be 1,75 m and at 0,96 1/min feed rate this distance shoud be 1,90 m; c- CDA 250, applying 27 1/ha presents large logistic advantages.

  15. 解读2015年度ENR国际承包商250强%Analysis on the ENR Top 250 International Contractors in 2015

    Institute of Scientific and Technical Information of China (English)

    张宇

    2015-01-01

    Based on the results of the ENR top 250 international Contractors in 2015,the analysis on the 250 international contractors was conducted from the revenue outside of their home countries,the profitability,the professional hiring,regional and market distribution in 2014. In the context of the global politics and economics environment,the highlights and trend of the development of international contracting market were concluded. On the contractors from mainland China in top 250,the number, influence and distribution were emphasized and the comparison from the last 5 years was done both on the mainland Chinese contractors and the top 10 international contractors. By the evaluation on the performance of the 250 international contractors and the discuss on the international engineering market,the recognition on the global competition of the contractors in mainland China would be promoted and their improvement in international contracting market could get useful information.%以美国《工程新闻记录》发布的2015年度国际承包商250强榜单数据为基础,对进入榜单的250家承包商的海外市场收入总体规模、效益、专业技术人员雇佣、业务领域分布、区域性市场及所属国家或地区进行了剖析.结合近期国际经济政治环境,对国际承包市场发展特征及趋势进行了总结和概括.重点分析了本年度进入250强榜单的中国内地企业承包商的数量、影响和行业及地区分布,并对近5年中国内地企业的表现进行了对比分析,同时对近5年国际承包商10强的变化进行了梳理.通过对国际承包市场要素的分析及对主要承包商业绩的评价,为中国内地企业增强对国际竞争的认识,继续开拓国际工程承包市场提供基础信息支持.

  16. 1:250,000-scale geology of the Carson River Basin, Nevada and California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digital continuous geologic data for the Carson River Basin, Nevada and California. It was compiled from individual county 1:250,000-scale...

  17. 41 CFR 60-250.44 - Required contents of affirmative action programs.

    Science.gov (United States)

    2010-07-01

    ... the workplace. (See § 60-250.2(w) defining direct threat.) (d) Reasonable accommodation to physical... career days, youth motivation programs, and related activities in their communities. (6) The...

  18. 1:250,000-scale geology of the Dry Valley Hydrographic Area, Nevada and California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This dataset consists of digital geologic data for the Dry Valley Hydrographic area, Nevada and California. It was compiled from individual 1:250,000-scale geologic...

  19. The p250GAP Gene Is Associated with Risk for Schizophrenia and Schizotypal Personality Traits

    OpenAIRE

    Kazutaka Ohi; Ryota Hashimoto; Takanobu Nakazawa; Takeya Okada; Yuka Yasuda; Hidenaga Yamamori; Motoyuki Fukumoto; Satomi Umeda-Yano; Masao Iwase; Hiroaki Kazui; Tadashi Yamamoto; Masanobu Kano; Masatoshi Takeda

    2012-01-01

    BACKGROUND: Hypofunction of the glutamate N-Methyl-d-aspartate (NMDA) receptor has been implicated in the pathophysiology of schizophrenia. p250GAP is a brain-enriched NMDA receptor-interacting RhoGAP. p250GAP is involved in spine morphology, and spine morphology has been shown to be altered in the post-mortem brains of patients with schizophrenia. Schizotypal personality disorder has a strong familial relationship with schizophrenia. Several susceptibility genes for schizophrenia have been r...

  20. Snow Cover Maps from MODIS Images at 250 m Resolution, Part 2: Validation

    OpenAIRE

    Marc Zebisch; Christian Steurer; Armin Costa; Roberto Monsorno; Thomas Schellenberger; Anke Tetzlaff; Martial Duguay; Nico Moelg; Claudia Notarnicola

    2013-01-01

    The performance of a new algorithm for binary snow cover monitoring based on Moderate Resolution Imaging Spectroradiometer (MODIS) satellite images at 250 m resolution is validated using snow cover maps (SCA) based on Landsat 7 ETM+ images and in situ snow depth measurements from ground stations in selected test sites in Central Europe. The advantages of the proposed algorithm are the improved ground resolution of 250 m and the near real-time availability with respect to the 500 m standard Na...

  1. Galvanic corrosion behaviour of HE 20 / MDN 138 & HE 20 / MDN 250 alloys in natural seawater

    Science.gov (United States)

    Subramanian, G.; Parthiban, G. T.; Muthuraman, K.; Ramakrishna rao, P.

    2016-09-01

    In view of their excellent mechanical properties, workability and heat treatment characteristics, MDN 138 & MDN 250 have been widely used in missile, rocket and aerospace industries. With light weight and high performance characteristics HE 20 aluminium alloy acts as an important material in defence and aerospace applications. The galvanic corrosion behaviour of the metal combinations HE 20 / MDN 138 and HE 20 / MDN 250, with 1:1 area ratio, has been studied in natural seawater using the open well facility of CECRI's Offshore Platform at Tuticorin for a year. The open circuit potentials of MDN 138, MDN 250 and HE 20 of the individual metal, the mixed potential and galvanic current of the couples HE 20 / MDN 138 and HE 20 / MDN 250 were periodically monitored throughout the study period. The calcareous deposits on MDN 138 and MDN 250 were analysed using XRD. The results of the study reveal that that HE 20 has offered required amount of protection to MDN 138 & MDN 250.

  2. Transmission of the P250R mutation of the FGFR3 gene in four generations with highly variable phenotype

    DEFF Research Database (Denmark)

    Hove, Hanne Buciek; Dunø, Morten; Daugaard-Jensen, Jette;

    Transmission of the P250R mutation of the FGFR3 gene in four generations with highly variable phenotype.......Transmission of the P250R mutation of the FGFR3 gene in four generations with highly variable phenotype....

  3. 30 CFR 250.107 - What must I do to protect health, safety, property, and the environment?

    Science.gov (United States)

    2010-07-01

    ..., property, and the environment? 250.107 Section 250.107 Mineral Resources MINERALS MANAGEMENT SERVICE... Performance Standards § 250.107 What must I do to protect health, safety, property, and the environment? (a) You must protect health, safety, property, and the environment by: (1) Performing all operations in...

  4. 30 CFR 250.116 - How do I determine producibility if my well is in the Gulf of Mexico?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I determine producibility if my well is in the Gulf of Mexico? 250.116 Section 250.116 Mineral Resources MINERALS MANAGEMENT SERVICE... Performance Standards § 250.116 How do I determine producibility if my well is in the Gulf of Mexico? If...

  5. 30 CFR 250.103 - Where can I find more information about the requirements in this part?

    Science.gov (United States)

    2010-07-01

    ... requirements in this part? 250.103 Section 250.103 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Authority and Definition of Terms § 250.103 Where can I find more information about the requirements in...

  6. 30 CFR 250.1006 - How must I decommission and take out of service a DOI pipeline?

    Science.gov (United States)

    2010-07-01

    ... a DOI pipeline? 250.1006 Section 250.1006 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pipelines and Pipeline Rights-of-Way § 250.1006 How must I decommission and take out of service a DOI...

  7. 17 CFR 250.12 - Exemption of certain public utility companies from the definition of subsidiary companies of...

    Science.gov (United States)

    2010-04-01

    ... utility companies from the definition of subsidiary companies of holding companies. 250.12 Section 250.12... REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General Exemptions § 250.12 Exemption of certain public utility companies from the definition of subsidiary companies of holding...

  8. 30 CFR 250.260 - What Coastal Zone Management Act (CZMA) information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ...) information must accompany the DPP or DOCD? 250.260 Section 250.260 Mineral Resources MINERALS MANAGEMENT... Operations Coordination Documents (docd) § 250.260 What Coastal Zone Management Act (CZMA) information must.... “Information” as required by 15 CFR 930.76(a) and 15 CFR 930.58(a)(2)) and “Analysis” as required by 15 CFR...

  9. Digitalna topografska karta 1:250 000 - prema NATO standardima / Digital 1:250 000 topographic map designed in accordance with NATO standards

    Directory of Open Access Journals (Sweden)

    Mirko Borisov

    2007-10-01

    Full Text Available U radu se iznose iskustva pri izradi i oblikovanju vojne topografske karte razmera 1: 250 000. Karta se izrađuje u Vojnogeografskom institutu, po NATO standardima i u digitalnom obliku. Iskustva drugih država u kreiranju vojnih topografsko-kartografskih sistema i karata mogu se uporediti sa našim. Postupci izrade i ažuriranja vojnih topografskih karata su informatički podržani uz veliki stepen automatizacije pojedinih faza njihove izrade i osavremenjavanja. / The paper presents the design of the 1:250 000 military topographic map in the Military Geographical Institute (MGI in accordance with NATO standards and in a digital form. Other states' experiences in designing military topographic and cartographic systems and maps can be compared with those of the MGI's. The procedures of producing and updating military topographic maps are computer aided while particular phases are automated to a great extent.

  10. The case for a generic phytosanitary irradiation dose of 250 Gy for Lepidoptera eggs and larvae

    International Nuclear Information System (INIS)

    The literature on ionizing irradiation of Lepidoptera is critically examined for a dose that could serve as a generic phytosanitary treatment for all eggs and larvae of that order, which contains many quarantine pests that inhibit trade in fresh agricultural commodities. The measure of efficacy used in deriving this dose is the prevention of emergence of normal-looking adults that are assumed not able to fly. A dose of 250 Gy is supported by many studies comprising 34 species in 11 lepidopteran families, including those of significant quarantine importance. Two studies with two different species found that doses >250 Gy were necessary, but both of these are contradicted by other studies showing that 10,000 individuals) testing for families other than Tortricidae (the most important quarantine family in the Lepidoptera). Because several large-scale studies have been done with tortricids a dose of 250 Gy could be justifiable for Tortricidae if it is not acceptable for the entire Lepidoptera at this time. - Highlights: • A radiation dose of 250 Gy is suggested as a generic phytosanitary treatment for Lepidoptera larvae. • The dose of 250 Gy is especially supported for the family Tortricidae. • The endpoint is prevention of normal-looking adults, assumed not able to fly or reproduce

  11. The faint end of the 250 micron luminosity function at z < 0.5

    CERN Document Server

    Wang, L; Bethermin, M; Bourne, N; Cooray, A; Cowley, W; Dunne, L; Dye, S; Eales, S; Farrah, D; Lacey, C; Loveday, J; Maddox, S; Oliver, S; Viero, M

    2016-01-01

    Aims. We aim to study the 250 micron luminosity function (LF) down to much fainter luminosities than achieved by previous efforts. Methods. We developed a modified stacking method to reconstruct the 250 micron LF using optically selected galaxies from the SDSS survey and Herschel maps of the GAMA equatorial fields and Stripe 82. Our stacking method not only recovers the mean 250 micron luminosities of galaxies that are too faint to be individually detected, but also their underlying distribution functions. Results. We find very good agreement with previous measurements in the overlapping luminosity range. More importantly, we are able to derive the LF down to much fainter luminosities (around 25 times fainter) than achieved by previous studies. We find strong positive luminosity evolution \\propto (1 + z)^4.89\\pm1.07 and moderate negative density evolution \\propto (1 + z)^-1.02\\pm0.54 over the redshift range z=[0.02, 0.5].

  12. Influence of solution cooling rate on austenite content of C250 steel%固溶冷却速率对C250钢奥氏体含量的影响

    Institute of Scientific and Technical Information of China (English)

    李伟

    2011-01-01

    试验了固溶冷却速率对C250钢奥氏体含量影响。试验结果表明,C250钢没有热稳定化现象,固溶后甚至缓慢冷却,也不会产生残留奥氏体。但固溶后缓慢冷却,再经时效强化处理,C250钢中将产生逆转变奥氏体,固溶冷却越缓慢,时效后的逆转变奥氏体量越多。C250钢固溶后空冷+485℃时效处理状态的没有奥氏体。%Influence of solution cooling rate on austenite content of C250 steel was investigated.The results show that there is no retained austenite in C250 steel solution treated even with very slowly cooling rate,and no austenite thermal stabilization phenomenon exists in C250 steel.But there is some reverted austenite in C250 steel aged when the solution cooling rate is very slow.The slower the solution cooling rate,the higher the content of reverted austenite in C250 steel aged.There is no reverted austenite in C250 steel solution treated with air cooling and aged at 485 ℃.

  13. The p250GAP gene is associated with risk for schizophrenia and schizotypal personality traits.

    Directory of Open Access Journals (Sweden)

    Kazutaka Ohi

    Full Text Available BACKGROUND: Hypofunction of the glutamate N-Methyl-d-aspartate (NMDA receptor has been implicated in the pathophysiology of schizophrenia. p250GAP is a brain-enriched NMDA receptor-interacting RhoGAP. p250GAP is involved in spine morphology, and spine morphology has been shown to be altered in the post-mortem brains of patients with schizophrenia. Schizotypal personality disorder has a strong familial relationship with schizophrenia. Several susceptibility genes for schizophrenia have been related to schizotypal traits. METHODS: We first investigated the association of eight linkage disequilibrium-tagging single-nucleotide polymorphisms (SNPs that cover the p250GAP gene with schizophrenia in a Japanese sample of 431 schizophrenia patients and 572 controls. We then investigated the impact of the risk genetic variant in the p250GAP gene on schizotypal personality traits in 180 healthy subjects using the Schizotypal Personality Questionnaire. RESULTS: We found a significant difference in genotype frequency between the patients and the controls in rs2298599 (χ(2 = 17.6, p = 0.00015. The minor A/A genotype frequency of rs2298599 was higher in the patients (18% than in the controls (9% (χ(2 = 15.5, p = 0.000083. Moreover, we found that subjects with the rs2298599 risk A/A genotype, compared with G allele carriers, had higher scores of schizotypal traits (F(1,178 = 4.08, p = 0.045, particularly the interpersonal factor (F(1,178 = 5.85, p = 0.017. DISCUSSION: These results suggest that a genetic variation in the p250GAP gene might increase susceptibility not only for schizophrenia but also for schizotypal personality traits. We concluded that the p250GAP gene might be a new candidate gene for susceptibility to schizophrenia.

  14. Making Planet Nine: Pebble Accretion at 250--750 AU in a Gravitationally Unstable Ring

    CERN Document Server

    Kenyon, Scott J

    2016-01-01

    We investigate the formation of icy super-Earth mass planets within a gravitationally unstable ring of solids orbiting at 250-750 AU around a 1 solar mass star. Coagulation calculations demonstrate that a system of a few large oligarchs and a swarm of pebbles generates a super-Earth within 100-200 Myr at 250 AU and within 1-2 Gyr at 750 AU. Systems with more than ten oligarchs fail to yield super-Earths over the age of the solar system. As these systems evolve, destructive collisions produce detectable debris disks with luminosities of $10^{-5}$ to $10^{-3}$ relative to the central star.

  15. Digitalna topografska karta 1:250 000 - prema NATO standardima / Digital 1:250 000 topographic map designed in accordance with NATO standards

    OpenAIRE

    Mirko Borisov

    2007-01-01

    U radu se iznose iskustva pri izradi i oblikovanju vojne topografske karte razmera 1: 250 000. Karta se izrađuje u Vojnogeografskom institutu, po NATO standardima i u digitalnom obliku. Iskustva drugih država u kreiranju vojnih topografsko-kartografskih sistema i karata mogu se uporediti sa našim. Postupci izrade i ažuriranja vojnih topografskih karata su informatički podržani uz veliki stepen automatizacije pojedinih faza njihove izrade i osavremenjavanja. / The paper presents the design of ...

  16. 未足月胎膜早破250例临床分析%Clinical analysis of preterm premature rupture of membranes 250 cases

    Institute of Scientific and Technical Information of China (English)

    季美芳

    2011-01-01

    Objective To analyze the incidence of preterm premature rupture of membranes causes and clinical treatment. Methods A retrospective analysis of January 2005 - December 2010 in our hospital the 250 patients clinical data with premature rupture of membranes at term. Results PPROM than in the composition of the relevant factors, reproductive tract infections up to 24.4% , followed by 22% fetal abnormalities, miscarriage, abortion history of 18. 8% ; 250 cases of vaginal delivery in patients with PPROM 112 cases, 44. 8% ; cesarean section in 138 cases, accounting for 55. 2% ; pregnant 28 to 31+6 weeks of the cesarean section rate of less than 32 to 34 pregnant and pregnant 6 weeks 35 to 36+6 weeks (P 0. 05). Conclusions For <34 weeks gestation PPROM prenatal tocolytic, glucocor-ticoids promote fetal lung maturity and antibiotics to prevent infections intervention to extend the gesta-tional age, to reduce perinatal complications and increase survival rate.%目的 分析研究未足月胎膜早破(PPROM)的发生原因以及临床处理方法.方法 回顾性分析2005年1月至2010年12月期间在本院住院治疗的250例未足月胎膜早破患者的临床资料.结果 PPROM相关因素的构成比中,生殖道感染最高24.4%,其次为胎位异常22%,流产、引产史18.8%;250例PPROM患者中阴道分娩112例,占44.8%;剖宫产138例,占55.2%;孕28 ~31+6周组的剖宫产率低于孕32 ~34+6周组和孕35 ~36+6周组(P<0.05);而孕32 ~34+6周组与孕35~36+6周组比较,无统计学意义(P>0.05).结论 对于小于34孕周的PPROM产前使用宫缩抑制剂、糖皮质激素促胎肺成熟及抗生素预防感染等于预,可延长孕龄,减少围产儿并发症,增加成活率.

  17. 17 CFR 250.103A - Liability for certain statements by issuers.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Liability for certain... Miscellaneous Rules § 250.103A Liability for certain statements by issuers. (a) A statement within the coverage... oil and gas reserves as set forth in paragraphs 30-34 of Statement of Financial Accounting...

  18. Tucumcari, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  19. Santa Fe, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  20. Gallup, NM AZ 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  1. Albuquerque, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  2. Raton, NM CO 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  3. Evaluation of GSt 250/350, Project-Oriented Field Study.

    Science.gov (United States)

    Lunneborg, Patricia W.; Mitchell, Sandra K.

    This report evaluates the effectiveness of an experiential field study course at the University of Washington. The course, titled GST 250/350, has different goals from a traditional volunteer program in that the student's education and experience are paramount; the services he provides are secondary. The student's motivation also differs somewhat…

  4. Hobbs, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  5. 30 CFR 250.462 - What are the requirements for well-control drills?

    Science.gov (United States)

    2010-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Other Drilling Requirements § 250.462 What are the requirements for well-control drills? You must conduct a weekly well-control drill with each drilling crew. Your drill must familiarize the crew with...

  6. 30 CFR 250.402 - When and how must I secure a well?

    Science.gov (United States)

    2010-07-01

    ... GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations General Requirements § 250.402 When and how must I secure a well? Whenever you interrupt drilling operations, you must...) Inability to keep the drilling rig on location; or (3) Repair to major drilling or well-control...

  7. 30 CFR 250.469 - What other well records could I be required to submit?

    Science.gov (United States)

    2010-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Applying for A Permit to Modify and Well Records § 250.469 What other well records could I be required to... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What other well records could I be required...

  8. Muusikamaailm. Maailmaesiettekanne Krimmis. Herderi preemiad 2002. Opera Metz 250. Günter Wand 90 / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2002-01-01

    Krimmis leiab aset Alemdar Karamanovi sümfoonia "Täideläinu" maailma esiettekanne. Johann Gottfried Herderi muusikapreemia sai nimekas rumeenia helilooja Aurel Stroe. Opera Metz Prantsusmaal tähistab oma 250ndat aastapäeva mitmete uuslavastustega. Dirigent Günter Wand tähistab 90ndat juubelit

  9. LCD OF AIR INTAKE MANIFOLDS PHASE 2: FORD F250 AIR INTAKE MANIFOLD

    Science.gov (United States)

    The life cycle design methodology was applied to the design analysis of three alternatives for the lower plehum of the air intake manifold for us with a 5.4L F-250 truck engine: a sand cast aluminum, a lost core molded nylon composite, and a vibration welded nylon composite. The ...

  10. 30 CFR 250.407 - What tests must I conduct to determine reservoir characteristics?

    Science.gov (United States)

    2010-07-01

    ... of oil, gas, sulphur, and water in the formations penetrated by logging, formation sampling, or well... OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations General Requirements § 250.407 What tests must I conduct to...

  11. 30 CFR 250.467 - How long must I keep records?

    Science.gov (United States)

    2010-07-01

    ... 250.467 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Applying for A... BOP tests Two years after the completion of drilling operations. (c) Completion of a well or of...

  12. 20 CFR 411.250 - How will SSA evaluate a PM?

    Science.gov (United States)

    2010-04-01

    ...) Business relations; and (5) Customer satisfaction. (b) Our Project Officer will perform the evaluation. The PM will have an opportunity to comment on the evaluation, and then the Contracting Officer will... Evaluation of Program Manager Performance § 411.250 How will SSA evaluate a PM? (a) We will...

  13. Aztec, NM CO 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  14. El Paso, TX NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  15. Socorro, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  16. 30 CFR 250.223 - What mitigation measures information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What mitigation measures information must... INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Contents of Exploration Plans (ep) § 250.223 What mitigation measures information must accompany the EP?...

  17. 30 CFR 250.254 - What mitigation measures information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What mitigation measures information must... Information Contents of Development and Production Plans (dpp) and Development Operations Coordination Documents (docd) § 250.254 What mitigation measures information must accompany the DPP or DOCD? (a) If...

  18. 30 CFR 250.215 - What hydrogen sulfide (H2S) information must accompany the EP?

    Science.gov (United States)

    2010-07-01

    ... methodologies outlined in 40 CFR part 68. ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What hydrogen sulfide (H2S) information must... Contents of Exploration Plans (ep) § 250.215 What hydrogen sulfide (H2S) information must accompany the...

  19. 17 CFR 250.23 - Procedure applicable to certain applications and declarations.

    Science.gov (United States)

    2010-04-01

    ... OF 1935 Forms, Procedure and Accounts § 250.23 Procedure applicable to certain applications and... Uniform System of Accounts for Public Utility Holding Companies. (b) Designation of filings as... a hearing be held, stating his reasons therefor and the nature of his interest....

  20. 17 CFR 250.26 - Financial statement and recordkeeping requirements for registered holding companies and...

    Science.gov (United States)

    2010-04-01

    ... accounts, books, or other records, except pursuant to 17 CFR part 257. (e) This rule shall not modify or... chart of accounts by the commission which promulgated it. The amendment shall describe the nature..., PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Forms, Procedure and Accounts § 250.26 Financial statement...

  1. 40 CFR 147.250 - State-administered program-Class II wells.

    Science.gov (United States)

    2010-07-01

    ... California § 147.250 State-administered program—Class II wells. The UIC program for Class II wells in the State of California, except those on Indian lands, is the program administered by the California... reference and made a part of the applicable UIC program under the SDWA for the State of California....

  2. 21 CFR 250.100 - Amyl nitrite inhalant as a prescription drug for human use.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Amyl nitrite inhalant as a prescription drug for... Prescription Status of Specific Drugs § 250.100 Amyl nitrite inhalant as a prescription drug for human use. (a) Amyl nitrite inhalant has been available over-the-counter for emergency use by the patient in...

  3. Potentiality evaluation of the MAT 250 UF mass spectrometer for general analysis

    International Nuclear Information System (INIS)

    This work presents a study on the potentiality of the MAT 250 UF mass spectrometer. It was formerly used only, for uranium isotopic analysis. It will be used, flow now on, also for the analysis of other gases such as deuterium, helium and hydrogen, as well. (A.C.A.S.)

  4. 30 CFR 250.114 - How must I install and operate electrical equipment?

    Science.gov (United States)

    2010-07-01

    .... (a) You must classify all areas according to API RP 500, Recommended Practice for Classification of... Division 2, or API RP 505, Recommended Practice for Classification of Locations for Electrical... (incorporated by reference as specified in § 250.198), or API RP 14FZ, Recommended Practice for Design...

  5. 30 CFR 250.113 - What procedures must I follow when welding?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What procedures must I follow when welding? 250....113 What procedures must I follow when welding? (a) Before you weld, you must move any equipment containing hydrocarbons or other flammable substances at least 35 feet horizontally from the welding...

  6. 30 CFR 250.111 - Who oversees operations under my welding plan?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who oversees operations under my welding plan... § 250.111 Who oversees operations under my welding plan? A welding supervisor or a designated person in charge must be thoroughly familiar with your welding plan. This person must ensure that each welder...

  7. 30 CFR 250.110 - What must I include in my welding plan?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my welding plan? 250.110... must I include in my welding plan? You must include all of the following in the Welding Plan that you... qualified personnel weld; (c) Practices and procedures for safe welding that address: (1) Welding...

  8. 30 CFR 250.1408 - When will I be notified of the Reviewing Officer's decision?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When will I be notified of the Reviewing... Continental Shelf (OCS) Civil Penalties § 250.1408 When will I be notified of the Reviewing Officer's decision... Reviewing Officer will review the case file, including all information you submitted, and send you...

  9. 50 CFR 216.250 - Specified activity and specified geographical region.

    Science.gov (United States)

    2010-10-01

    ... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE... Weapon Missions in the Gulf of Mexico § 216.250 Specified activity and specified geographical region. (a... within the Eglin Air Force Base Gulf Test and Training Range within the northern Gulf of Mexico....

  10. Comparison of differences between MODIS 250 m and 1 km cloud masks

    Science.gov (United States)

    Kotarba, Andrzej Z.

    2016-11-01

    The spatial resolution of remote sensing instruments installed onboard satellites is one of the key factors for accurate estimations of cloud amount. In general terms, the larger the instantaneous field of view (IFOV), the greater the overestimation of cloud amount - assuming that data are collected with exactly the same methodology, and processed with exactly the same algorithms. While most meteorological imagers collect data at a spatial resolution of 1 km, the Moderate Resolution Imaging Spectroradiometer (MODIS) offers cloud amount estimates at both 1 km (the standard product) and 250 m (additional, high-resolution products). However, these datasets are produced using different methodological approaches, which impacts the quality and reliability of the product. This study compared 250 m data with 1 km data over elevated terrain with complex orography. Results showed significant discrepancies between the datasets, with 250 m data reporting mean seasonal (June-August) cloud amount 15.8% lower, than 1 km dataset. This was not related to the presence of snow, or to the increased spatial resolution of the cloud mask. On the other hand, both 1 km and 250 m data described similar spatial variability in mean monthly cloud amount (correlation coefficients of 0.85-0.98, p < 0.01).

  11. 30 CFR 250.901 - What industry standards must your platform meet?

    Science.gov (United States)

    2010-07-01

    ..., Building Code Requirements for Reinforced Concrete (ACI 318-95) and Commentary (ACI 318R-95) (incorporated..., Specification for Structural Steel Buildings, (incorporated by reference as specified in § 250.198); (4...); (22) AWS D3.6M, Specification for Underwater Welding, (incorporated by reference as specified in §...

  12. 30 CFR 250.1165 - What must I do for enhanced recovery operations?

    Science.gov (United States)

    2010-07-01

    ... Supervisor and receive approval for pressure maintenance, secondary or tertiary recovery, cycling, and... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I do for enhanced recovery operations... Requirements Other Requirements § 250.1165 What must I do for enhanced recovery operations? (a) You...

  13. 30 CFR 250.518 - What are the requirements for casing pressure management?

    Science.gov (United States)

    2010-07-01

    ... Operations Casing Pressure Management § 250.518 What are the requirements for casing pressure management? Once you install your wellhead, you must meet the casing pressure management requirements of API RP 90... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the requirements for casing...

  14. 30 CFR 250.1717 - After I permanently plug a well, what information must I submit?

    Science.gov (United States)

    2010-07-01

    ... Decommissioning Activities Permanently Plugging Wells § 250.1717 After I permanently plug a well, what information must I submit? Within 30 days after you permanently plug a well, you must submit form MMS-124... 30 Mineral Resources 2 2010-07-01 2010-07-01 false After I permanently plug a well,...

  15. 30 CFR 250.1753 - After I decommission a pipeline, what information must I submit?

    Science.gov (United States)

    2010-07-01

    ... Decommissioning Activities Pipeline Decommissioning § 250.1753 After I decommission a pipeline, what information must I submit? Within 30 days after you decommission a pipeline, you must submit a written report to... 30 Mineral Resources 2 2010-07-01 2010-07-01 false After I decommission a pipeline,...

  16. Comparing the Effect of Different Bleaching Regims of Carbamide Peroxide on Microhardness of Z250 Composite

    Directory of Open Access Journals (Sweden)

    B Esmaeili

    2015-11-01

    Full Text Available Introduction: Bleaching products with oxidizing mechanism can exert side effects on the restorative materials existing in the oral cavity. Since bleaching agents are applied in different concentrations, the present study aimed to compare the effect of different bleaching regims of carbamide peroxide on microhardness of Z250 microhybride composite. Methods: In this in vitro study , 32 specimens of micro hybride composite (Z250 were made which were randomly divided into 4 subgroups (n=8: G1: bleached with10% carbamide peroxide 4 hours a day for 2 weeks G2: bleached with 16%carbamide peroxide 3 hours a day for 2 weeks G3: bleached with 22%carbamide peroxide 1hour a day for 2 weeks G4: the control subgroup stored in distilled water at 37◦c for 2 weeks. Microhardness of specimens was measured before and after bleaching using Vickers hardness testing machine. Moreover, the study data were analyzed statistically applying Anova and t-test (&alpha= 0.05. Results: This study findings revealed that using bleaching agent significantly decreased the  microhardness of composite resin in the bleaching groups compared to the control group, though the concentration of carbamide peroxide produced no significant effect on the microhardness value. (p>0.13 Conclusion: Bleaching therapy can cause a reduction in microhardness of Z250 composite and different concentrations of carbamide peroxide can reduce microhardness of Z250 to the same value.

  17. Analysis of wind power ancillary services characteristics with German 250-MW wind data

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, B.

    1999-12-09

    With the increasing availability of wind power worldwide, power fluctuations have become a concern for some utilities. Under electric industry restructuring in the US, the impact of these fluctuations will be evaluated by examining provisions and costs of ancillary services for wind power. This paper analyzes wind power in the context of ancillary services, using data from a German 250 Megawatt Wind project.

  18. HIVAP calculations for the synthesis of new isotopes of Z=116 and Z=118 through 250Cm(48Ca, xn) and 250-252Cf(48Ca, xn) reactions

    International Nuclear Information System (INIS)

    The production and study of superheavy elements is an important area of research in contemporary experimental nuclear physics. The heaviest element produced so far is Z=118 (one isotope with A=294) in the 48Ca + 249Cf reaction with a production cross-section of 0.5 pico barns. Here we propose 250Cm(48Ca, xn) and 250-252Cf(48Ca, xn) reactions for the synthesis of heavier isotopes of Z=116 and 118 with comparable theoretical production cross-sections. 250Cm, 250Cf, 251Cf and 252Cf are feasible targets with half lives of 8300, 13.1, 898 and 2.6 years respectively

  19. Revamp of cable reel on 250 t converter ladle car%250 t转炉钢包车电缆卷筒改造

    Institute of Scientific and Technical Information of China (English)

    叶国英

    2014-01-01

    In view of the problems of burning the cable and the cable reel not running in No.3 Branch of General Steel-making Plant of WISCO,which led to the maintenance cost rising and affected the production,the drive way of cable reel and the cable sizing were optimized in 250 t converter ladle car.After that,the maintenance cost is de-creased deeply,and only 2 cables are needed by a ladle car every year,which ensure the normal production.%针对武钢炼钢总厂三分厂经常出现电缆烧损、电缆卷筒不转故障导致维修成本上升且影响生产的问题,对250 t转炉钢包车电缆卷筒的传动方式、电缆选型进行了改造。改造后,每台钢包车每年只需更换2根电缆,大大降低了维护成本,保证了生产的正常运行。

  20. KP-250螺旋挤压式固液分离机的设计及试验%Design and Experiment of KP-250 Screw Separator

    Institute of Scientific and Technical Information of China (English)

    申江涛; 吴德胜; 赵明杰; 蒋建群; 马学良; 郭楠

    2014-01-01

    Manure pollution problems of livestock and poultry farms has raised concern in the whole society , therefore , the government are paying more and more attention to environment protection of livestock and poultry farms .How to solve the manure pollution problem in condition of not affecting the production efficiency or even can improve the economic benefit of the farms has become a top priority .Screw separator is a new kind of separation device , has the function of gravity filtration、squeezing filtration and high pressure squeeze .It can successfully crack this problem .This article illus-trated the overall structure and working principle of KP-250 screw separator ,analyzed the key problems in the process of designing screw separator .It also studied and designed the general structure ,screw squeezing device ,screen mesh ,the gap between the screw and the screen ,discharging device and drive system .Test results indicated that :KP-250 screw separator was designed reasonable ,safe and reliable .It was suitable for solving the manure pollution problems of farms ( cattle and pig farms ) ,and so as to promote the development of environmental protection career of modern livestock and poultry farm .%养殖场畜禽粪便污染问题已经蔓延成为全社会关注的问题,国家对养殖场的环保越来越重视。如何在不影响养殖场生产效益抑或能提高养殖场经济效益的前提下解决粪污处理的难题,成为了当务之急。螺旋挤压式固液分离机是将重力过滤、挤压过滤以及高压压榨融为一体的新型分离装置,可成功破解这一难题。为此,阐述了KP-250螺旋挤压式固液分离的总体结构和工作原理,分析了固液分离机设计所要解决的关键问题。对总体结构、螺旋挤压结构、筛网、螺旋和筛网的间隙、出料装置及驱动系统进行了研究和设计。试验结果表明:KP-250固液分离机设计合理,安全可靠,适用于养殖场(养

  1. A 14-bit 250-MS/s current-steering CMOS digital-to-analog converter

    Institute of Scientific and Technical Information of China (English)

    Li Xueqing; Fan Hua; Wei Qi; Xu Zhen; Liu Jianan; Yang Huazhong

    2013-01-01

    A 14-bit 250-MS/s current-steering digital-to-analog converter (DAC) was fabricated in a 0.13 μm CMOS process.In conventional high-speed current-steering DACs,the spurious-free dynamic range (SFDR) is limited by nonlinear distortions in the code-dependent switching glitches.In this paper,the bottleneck is mitigated by the time-relaxed interleaving digital-random-return-to-zero (TRI-DRRZ).Under 250-MS/s sampling rate,the measured SFDR is 86.2 dB at 5.5-MHz signal frequency and 77.8 dB up to 122 MHz.The DAC occupies an active area of 1.58 mm2 and consumes 226 mW from a mixed power supply of 1.2/2.5 V.

  2. First demonstration of a vehicle mounted 250GHz real time passive imager

    Science.gov (United States)

    Mann, Chris

    2009-05-01

    This paper describes the design and performance of a ruggedized passive Terahertz imager, the frequency of operation is a 40GHz band centred around 250GHz. This system has been specifically targeted at vehicle mounted operation, outdoors in extreme environments. The unit incorporates temperature stabilization along with an anti-vibration chassis and is sealed to allow it to be used in a dusty environment. Within the system, a 250GHz heterodyne detector array is mated with optics and scanner to allow real time imaging out to 100 meters. First applications are envisaged to be stand-off, person borne IED detection to 30 meters but the unique properties in this frequency band present other potential uses such as seeing through smoke and fog. The possibility for use as a landing aid is discussed. A detailed description of the system design and video examples of typical imaging output will be presented.

  3. Debye relaxation and 250 K anomaly in glass forming monohydroxy alcohols

    CERN Document Server

    Bauer, S; Gainaru, C; Lunkenheimer, P; Hiller, W; Loidl, A; Böhmer, R

    2013-01-01

    A previous dielectric, near-infrared (NIR), and nuclear magnetic resonance study on the hydrogen-bonded liquid 2-ethyl-1-hexanol [C. Gainaru et al., Phys. Rev. Lett. 107, 118304 (2011)] revealed anomalous behavior in various static quantities near 250 K. To check whether corresponding observations can be made for other monohydroxy alcohols as well, these experimental methods were applied to such substances with 5, 6, 7, 8, and 10 carbon atoms in their molecular backbone. All studied liquids exhibit a change of behavior near 250 K which is tentatively ascribed to effects of hydrogen bond cooperativity. By analyzing the NIR band intensities, a linear cluster size is derived that agrees with estimates from dielectric spectroscopy. All studied alcohols, except 4-methyl-3-heptanol, display a dominant Debye-like peak. Furthermore, neat 2-ethyl-1-butanol exhibits a well resolved structural relaxation in its dielectric loss spectrum which so far has only been observed for diluted monohydroxy alcohols.

  4. A low-power 10-bit 250-KSPS cyclic ADC with offset and mismatch correction*

    Institute of Scientific and Technical Information of China (English)

    Zhao Hongliang; Zhao Yiqiang; Geng Junfeng; Li Peng; Zhang Zhisheng

    2011-01-01

    A low power 10-bit 250-k sample per second (KSPS) cyclic analog to digital converter (ADC) is presented. The ADC's offset errors are successfully cancelled out through the proper choice of a capacitor switching sequence. The improved redundant signed digit algorithm used in the ADC can tolerate high levels of the comparator's offset errors and switched capacitor mismatch errors. With this structure, it has the advantages of simple circuit configuration, small chip area and low power dissipation. The cyclic ADC manufactured with the Chartered 0.35 μm 2P4M process shows a 58.5 dB signal to noise and distortion ratio and a 9.4 bit effective number of bits at a 250 KSPS sample rate. It dissipates 0.72 mW with a 3.3 V power supply and occupies dimensions of 0.42 × 0.68 mm2.

  5. New evidence for 250 Ma age of halotolerant bacterium from a Permian salt crystal

    Science.gov (United States)

    Satterfield, Cindy L.; Lowenstein, Tim K.; Vreeland, Russell H.; Rosenzweig, William D.; Powers, Dennis W.

    2005-04-01

    The purported oldest living organism, the spore-forming bacterium Virgibacillus sp. Permian strain 2 9-3, was recently cultured from a brine inclusion in halite of the 250 Ma Permian Salado Formation. However, the antiquity of Virgibacillus sp. 2 9-3 has been challenged; it has been argued that the halite crystal and the fluid inclusion from which the bacterial spores were extracted may be younger than the Permian Salado salts. Here we report that brine inclusions from the same layer of salt that housed Virgibacillus sp. 2 9-3 are composed of evaporated Late Permian seawater that was trapped in halite cement crystals precipitated syndepositionally from shallow groundwater brines at temperatures of 17 37 °C. These results support the 250 Ma age of the fluid inclusions, and by inference, the long-term survivability of microorganisms such as Virgibacillus sp. 2 9-3.

  6. Dispersive spherical optical model of neutron scattering from Al27 up to 250 MeV

    CERN Document Server

    Molina, A; Quesada, J M; Lozano, M

    2002-01-01

    A spherical optical model potential (OMP) containing a dispersive term is used to fit the available experimental database of angular distribution and total cross section data for n + Al27 covering the energy range 0.1- 250 MeV using relativistic kinematics and a relativistic extension of the Schroedinger equation. A dispersive OMP with parameters that show a smooth energy dependence and energy independent geometry are determined from fits to the entire data set. A very good overall agreement between experimental data and predictions is achieved up to 150 MeV. Inclusion of nonlocality effects in the absorptive volume potential allows to achieve an excellent agreement up to 250 MeV.

  7. A 250 GHz Gyrotron with a 3 GHz Tuning Bandwidth for Dynamic Nuclear Polarization

    OpenAIRE

    Barnes, Alexander B.; Nanni, Emilio A.; Herzfeld, Judith; Griffin, Robert G.; Temkin, Richard J.

    2012-01-01

    We describe the design and implementation of a novel tunable 250 GHz gyrotron oscillator with >10 W output power over most of a 3 GHz band and >35 W peak power. The tuning bandwidth and power are sufficient to generate a >1 MHz nutation frequency across the entire nitroxide EPR lineshape for cross effect DNP, as well as to excite solid effect transitions utilizing other radicals, without the need for sweeping the NMR magnetic field. Substantially improved tunability is achieved by implementin...

  8. On the economic dimensions of CSR: Exploring Fortune Global 250 reports

    OpenAIRE

    Fortanier, F.N.; Kolk, A.

    2007-01-01

    The macro-level debate on the economic impact of multinational enterprises (MNEs) is still unsettled. This article explores micro-level evidence by examining what Fortune Global 250 firms themselves report about their economic impact. Such reporting embodies corporate attempts to account for their economic implications, in addition to the environmental and social aspects of their activities that have traditionally received more attention in the context of corporate responsibility. Firms' repo...

  9. Clinical analysis of 250 cases of ultrasound-guided percutaneous fine needle aspiration of pancreatic mass

    Institute of Scientific and Technical Information of China (English)

    王仕迎

    2014-01-01

    Objective To assess the accuracy and safety of cytopathological diagnosis of ultrasound guided fine needle aspirated(US-FNA)pancreatic masses.Methods From January 2008 to February 2013,250 pancreatic mass cases underwent US-FNA and with cytopathological diagnosis were retrospectively analyzed.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy were calculated.The stratified analysis of

  10. Impulsore Chresto. Opposition to Christianity in the Roman Empire c. 50-250 AD

    DEFF Research Database (Denmark)

    Engberg, Jakob

    Impulsore Chresto reassesses opposition to Christianity AD 50-250. The Roman authorities' persecutions have caught the attention of both the public, intrigued by martyrs, and scholars, arguing that executions were relatively rare. The latter is not challenged, but the executions are placed in con......, spectators or local officials were crucial. There were as many reasons for opposition as opponents, but some motives reappear in clusters: Christians were perceived as superstitious and ungodly, as endangering peace with the gods and social order....

  11. Adsorption of Sulfamethazine from Environmentally Relevant Aqueous Matrices onto Hypercrosslinked Adsorbent MN250.

    Science.gov (United States)

    Grimmett, Maria E

    2015-07-01

    Four hundred tons of sulfamethazine are fed to livestock annually in North America for disease prevention and growth promotion, but the majority is excreted unmetabolized into the environment. Due to its slow degradation and high mobility, sulfamethazine contaminates groundwater and causes aquatic ecosystem damage. Sulfamethazine remediation methods are not universally effective, necessitating newer techniques. Hypercrosslinked polystyrene adsorbents show promise because of high surface areas, durability, and regenerable properties. Using batch techniques, sulfamethazine adsorption onto Purolite MN250 was evaluated in the presence of dissolved humic acid and under variable pH and ionic strength. The adsorption capacity () of MN250 for sulfamethazine with humic acid was 109.3 mg g. In simulated groundwater, at pH 5 was 51 to 62% higher than at pH 9. The maximum at pH 7 (144.0 mg g) exceeded pH 5 performance (128.3 mg g). In 0.005 M KCl, was 181.0 mg g, which decreased by 34% in 0.05 M KCl. In 0.5 M, KCl, (153.4 mg g) increased 26% over 0.05 M KCl. For all matrices, equilibration was attained between 120 and 168 h, best fit by Ho's pseudo-second-order model. Overall, is pH dependent because the sulfamethazine speciation and the zeta potential of MN250 vary as a function of pH. Increasing ionic strength initially decreases by altering the activity coefficient of sulfamethazine and by altering the properties of the electrical double layer, while salting-out becomes prominent at seawater concentration. MN250's high sulfamethazine capacity in environmentally relevant aqueous matrices highlights its potential for groundwater remediation. PMID:26437099

  12. Women in the Boardrooms of FTSE 250 Companies and Their Impact on Firm Performance

    OpenAIRE

    Kingham, Ashley

    2015-01-01

    The purpose of this study was to examine whether there is a relationship between the amount of female directors on the boards of FTSE 250 companies and the observed companies’ performance. Previous researchers have had mixed results and differing opinions on the effects of this relationship, with papers finding positive and negative relationships, there are also several notable papers finding no relationship at all between these two factors. This study was carried out using data from 201...

  13. 12 CFR 250.401 - Director serving member bank and closed-end investment company being organized.

    Science.gov (United States)

    2010-01-01

    ... that a closed-end company which was in process of organization and was actively engaged in issuing and... investment company being organized. 250.401 Section 250.401 Banks and Banking FEDERAL RESERVE SYSTEM... company being organized. (a) The Board has previously expressed the opinion (§ 218.101) that section 32...

  14. 12 CFR 250.412 - Interlocking relationships between member bank and insurance company-mutual fund complex.

    Science.gov (United States)

    2010-01-01

    ... mutual fund shares and life insurance policies that would provide increased competitive strength in a... Fund, Inc. (“Fund”), the mutual fund, was closely related to X Life Insurance Company (“Insurance... and insurance company-mutual fund complex. 250.412 Section 250.412 Banks and Banking FEDERAL...

  15. 75 FR 62919 - Notice of Final Federal Agency Actions on the Route 250 Bypass Interchange at McIntire Road...

    Science.gov (United States)

    2010-10-13

    ... of Route 250 Bypass and McIntire Road. The project would reduce traffic congestion and improve... at McIntire Road Project in Virginia AGENCY: Federal Highway Administration (FHWA), DOT. ACTION... the Route 250 Bypass Interchange at McIntire Road project in the City of Charlottesville,...

  16. Geluidimmissie van Thalys en Ansaldo V250 treinen op het HSL spoor bij twee woningen in Kaag en Braassem

    NARCIS (Netherlands)

    Hof, J. van 't; Staats, F.; Graafland, F.; Prevo, R.

    2014-01-01

    TNO heeft in opdracht van ProRail de geluidimmissieniveaus gemeten van de Ansaldo V250 en de Thalys hogesnelheidstreinen die op het spoor van de HSL-Zuid met hoge snelheid rijden, bij twee woningen in de gemeente Kaag en Braassem. Tijdens dit onderzoek rijden er treinen van het type Ansaldo V250, Th

  17. 12 CFR 250.141 - Member bank purchase of stock of “operations subsidiaries.”

    Science.gov (United States)

    2010-01-01

    ... other words, a wholly owned subsidiary corporation engaged in activities that the bank itself may... the bank either directly, or indirectly through a wholly-owned subsidiary corporation. (j) This... subsidiaries.â 250.141 Section 250.141 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF...

  18. 30 CFR 250.150 - How do I name facilities and wells in the Gulf of Mexico Region?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I name facilities and wells in the Gulf of Mexico Region? 250.150 Section 250.150 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... and wells in the Gulf of Mexico Region? (a) Assign each facility a letter designation except for...

  19. 30 CFR 250.248 - What solid and liquid wastes and discharges information and cooling water intake information must...

    Science.gov (United States)

    2010-07-01

    ... information and cooling water intake information must accompany the DPP or DOCD? 250.248 Section 250.248... and discharges information and cooling water intake information must accompany the DPP or DOCD? The following solid and liquid wastes and discharges information and cooling water intake information...

  20. 30 CFR 250.217 - What solid and liquid wastes and discharges information and cooling water intake information must...

    Science.gov (United States)

    2010-07-01

    ... information and cooling water intake information must accompany the EP? 250.217 Section 250.217 Mineral... What solid and liquid wastes and discharges information and cooling water intake information must accompany the EP? The following solid and liquid wastes and discharges information and cooling water...

  1. Silicon epitaxy on H-terminated Si (100) surfaces at 250 °C

    Science.gov (United States)

    Deng, Xiao; Namboodiri, Pradeep; Li, Kai; Wang, Xiqiao; Stan, Gheorghe; Myers, Alline F.; Cheng, Xinbin; Li, Tongbao; Silver, Richard M.

    2016-08-01

    Low temperature Si epitaxy has become increasingly important due to its critical role in the encapsulation and performance of buried nanoscale dopant devices. We demonstrate epitaxial growth up to nominally 25 nm, at 250 °C, with analysis at successive growth steps using STM and cross section TEM to reveal the nature and quality of the epitaxial growth. STM images indicate that growth morphology of both Si on Si and Si on H-terminated Si (H: Si) is epitaxial in nature at temperatures as low as 250 °C. For Si on Si growth at 250 °C, we show that the Si epitaxial growth front maintains a constant morphology after reaching a specific thickness threshold. Although the in-plane mobility of silicon is affected on the H: Si surface due to the presence of H atoms during initial sub-monolayer growth, STM images reveal long range order and demonstrate that growth proceeds by epitaxial island growth albeit with noticeable surface roughening.

  2. Shielding calculations for a 250 MeV hospital-based proton accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Agosteo, S. [Politecnico di Milano (Italy). Ist. di Ingegneria Nucleare; Arduini, G. [Fondazione Italiana Ricerca sul Cancro, via Corridoni 7, 20122 Milano (Italy); Bodei, G. [Politecnico di Milano (Italy). Ist. di Ingegneria Nucleare; Monti, S. [ENEA, ERG-FISS-FIRE, via Martiri di Monte Sole 4, 40129 Bologna (Italy); Padoani, F. [ENEA, ERG-FISS-FIRE, via Martiri di Monte Sole 4, 40129 Bologna (Italy); Silari, M. [Consiglio Nazionale delle Ricerche, Istituto Tecnologie Biomediche Avanzate, via Ampere 56, I-20131, Milano (Italy); Tinti, R. [ENEA, ERG-FISS-FIRE, via Martiri di Monte Sole 4, 40129 Bologna (Italy); Tromba, G. [Sincrotrone (``ELETTRA``) Trieste, Padriciano 99, 34012 Trieste (Italy)

    1996-05-21

    The accelerator shields (250 MeV protons, 400 MeV/u {sup 16}O{sup 8+} ions) and treatment rooms of the Hadrontherapy Centre, a hospital-based facility under design in Italy, were determined by means of Monte Carlo calculations. The LCS and FLUKA codes were employed, together with analytical estimates carried out by making use of empirical formulas from the literature, and the results compared. In the case of 250 MeV protons a 250 cm thick concrete wall ensures an annual dose equivalent lower than 2 mSv in the environments adjacent to the accelerator room. The best ceiling thickness was found to be 200 cm for a unitary occupancy factor. The photon dose equivalent beyond the concrete shield was also estimated using the LCS code. In the case of ions the shield thickness was calculated using empirical formulas from the literature; the concrete thicknesses calculated for protons should ensure the required dose equivalent when some local shields are added. Monte Carlo calculations of the treatment room shielding were also carried out using the FLUKA code. (orig.).

  3. A 250 GHz Survey of High Redshift QSOs from the Sloan Digital Sky Survey

    CERN Document Server

    Carilli, C L; Rupen, M P; Fan, X; Strauss, M A; Menten, K M; Kreysa, E; Schneider, D P; Bertarini, A; Yun, M S; Zylka, R; Fan, Xiaohui; Strauss, Michael A.; Schneider, Donald P.

    2001-01-01

    We present observations at 250 GHz (1.2 mm), 43 GHz, and 1.4 GHz of a sample of 41 QSOs at z > 3.7 found in the Sloan Digital Sky Survey. We detect 16 sources with a 250 GHz flux density greater than 1.4 mJy. The combination of centimeter and millimeter wavelength observations indicates that the 250 GHz emission is most likely thermal dust emission. Assuming a dust temperature of 50 K, the implied dust masses for the 16 detected sources are in the range 1.5e8 to 5.9e8 Msun, and the dust emitting regions are likely to be larger than 1 kpc in extent. The radio-through-optical spectral energy distributions for these sources are within the broad range defined by lower redshift, lower optical luminosity QSOs. We consider possible dust heating mechanisms, including UV emission from the active nucleus (AGN) and a starburst concurrent with the AGN, with implied star formation rates between 500 and 2000 Msun/year.

  4. p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation.

    Directory of Open Access Journals (Sweden)

    Madhuvanthi Kannan

    Full Text Available Axon growth is an essential process during brain development. The E3 ubiquitin ligase Cdh1-APC has emerged as a critical regulator of intrinsic axon growth control. Here, we identified the RhoGAP p250GAP as a novel interactor of the E3 ubiquitin ligase Cdh1-APC and found that p250GAP promotes axon growth downstream of Cdh1-APC. We also report that p250GAP undergoes non-proteolytic ubiquitination and associates with the Cdh1 substrate Smurf1 to synergistically regulate axon growth. Finally, we found that in vivo knockdown of p250GAP in the developing cerebellar cortex results in impaired migration and axonal growth. Taken together, our data indicate that Cdh1-APC together with the RhoA regulators p250GAP and Smurf1 controls axon growth in the mammalian brain.

  5. Oxidation-reduction properties of americium, curium, berkelium, californium, einsteinium and fermium, and thermodynamic consequences for the 5f series

    International Nuclear Information System (INIS)

    The amalgamation of 5f elements from Am to Fm has been studied by using 241Am, 244Cm, 249Bk, 249Cf, 252Cf, 253Es, 254Es, 252Fm and 255Fm with two electrochemical methods, radiocoulometry and radiopolarography, perfectly adapted to investigate extremely diluted solutions when the concentration of electroactive species is as low as 10-16M. The theory of radiocoulometry has been developed in the general cases of reversible and irreversible electrode process. It has been used to interpret the experimental data on the kinetic curves of amalgamation, and to estimate the standard rate constant of the electrode process in complexing medium (citric). On the other hand the radiopolarographic method has been applied to study the mechanism of reduction at the dropping mercury electrode of cations M3+ in aqueous medium to the metal M with formation of amalgam. The results are exploited into two directions: 1- Acquisition of some data concerning the oxidation-reduction properties of elements from Am to Fm. Therefore the standard electrode E0 [M(III-0)] potentials for Bk, Cf and Es, and the standard electrode E0 [M(II-0)] potential for Fm are estimated and the relative stability of each oxidation state (from II to VII) of 5f elements is discussed; 2- Acquisition of unknown thermodynamic data on transcalifornium elements. Correlations between 4f and 5f elements are precised and some divergences appear for the second half of 4f and 5f series (i.e. for 65<=Z<=71 and 97<=Z<=103)

  6. An Analysis of 250 MDMA Addicts%250例苯丙胺类摇头丸(MDMA)滥用人群分析

    Institute of Scientific and Technical Information of China (English)

    孙毅; 徐本树; 王志强; 金俊; 吕秋霖; 张惠民

    2004-01-01

    目的:了解苯丙胺类物质摇头丸(MDMA)滥用人群人口学特征及其MDMA的精神活性作用.方法:制定统一问卷,对2001年1月-2002年11月在我院住院MDMA滥用者逐一进行登记.结果:总共调查250例摇头丸(MDMA)滥用者.250例MDMA滥用者平均年龄27.25±7.46 a.未婚青年女性141例,占总例数56.6%.文化程度较高,高中以上文化程度165例,占总例数66.04%.滥用方式大多数以啤酒送服,其次是矿泉水、饮料.滥用场所以歌厅和迪厅为主.每周使用2次以上者97例,占38.68%.MDMA的起效时间为25.61±11.06 min,作用持续时间为3.44±1.68 h.滥用后主观感受及行为表现依次为出汗、头晕、口干、心情愉快等.MDMA作用消失后部分滥用者表现为失眠、食欲下降、记忆力减退、厌食、疲乏、睡眠增多、食欲增大等.结论:近年来MDMA滥用者有增多趋势,部分滥用者有向强制性用药的模式趋势发展,应引起人们足够重视.

  7. Improved design of a certaintype GO-Kart of 250 ml discharge%250 ml排量卡丁车的改进设计

    Institute of Scientific and Technical Information of China (English)

    徐振宇; 陈益帅

    2011-01-01

    为解决目前最受市场欢迎的250 ml排量系列卡丁车"减振性能差、在崎岖路面高速行驶稳定性不佳"的问题,将高档轿车上用的双摆臂前轮悬架设计技术整合到这一排量的卡丁车中去,同时改变以往后轮单纯依靠橡胶轮胎减振的情况,后悬架采用整体桥式结构重新设计.在改进设计中开展了卡丁车前、后悬架减振器速度特性试验、等效刚度试验、悬架总体侧倾角刚度试验,提出了将计算机三维设计与试制、试验相结合的改进设计方法.对改进设计前后的减振器阻尼、悬架等效刚度及悬架总体侧倾刚度值的变化进行了评价,并完成了整车试制后的路面测试.试验结果表明,改进后的卡丁车大大提高了崎岖路面行驶的稳定性和平顺性.%In order to solve the problems of poor stability on rugged roads during high - speed driving, as well as poor damping performance of the most popular Kart ( displacement: 250 ml), the following areas were investigated: the double-arm front wheel suspension design of luxury sedans was integrated into the Kart. The past situation of relying solely on the rear wheel damping was changed. And the rear suspension was redesigned with the overall bridge structure. After the tests of the front and rear suspension damper rate, the equivalent stiffness, and the overall roll angle suspension stiffness, the method of combining computer three-dimensional design, trial-manufacture and tests was presented. The absorber's damping, suspension equivalent stiffness and overall roll angle suspension stiffness before and after design improvement were evaluated, and the finished trial - manufactured Kart was tested on the road. The experimental results show that the stability and smoothness of the Kart had been greatly enhanced when it is on rough roads.

  8. Increased N250 amplitudes for other-race faces reflect more effortful processing at the individual level.

    Science.gov (United States)

    Herzmann, Grit

    2016-07-01

    The N250 and N250r (r for repetition, signaling a difference measure of priming) has been proposed to reflect the activation of perceptual memory representations for individual faces. Increased N250r and N250 amplitudes have been associated with higher levels of familiarity and expertise, respectively. In contrast to these observations, the N250 amplitude has been found to be larger for other-race than own-race faces in recognition memory tasks. This study investigated if these findings were due to increased identity-specific processing demands for other-race relative to own-race faces and whether or not similar results would be obtained for the N250 in a repetition priming paradigm. Only Caucasian participants were available for testing and completed two tasks with Caucasian, African-American, and Chinese faces. In a repetition priming task, participants decided whether or not sequentially presented faces were of the same identity (individuation task) or same race (categorization task). Increased N250 amplitudes were found for African-American and Chinese faces relative to Caucasian faces, replicating previous results in recognition memory tasks. Contrary to the expectation that increased N250 amplitudes for other-race face would be confined to the individuation task, both tasks showed similar results. This could be due to the fact that face identity information needed to be maintained across the sequential presentation of prime and target in both tasks. Increased N250 amplitudes for other-race faces are taken to represent increased neural demands on the identity-specific processing of other-race faces, which are typically processed less holistically and less on the level of the individual. PMID:27184183

  9. Pulse radiolysis studies of liquid heavy water at temperatures up to 250 degrees C

    Energy Technology Data Exchange (ETDEWEB)

    Stuart, C.R.; Ouellette, D.C.; Elliot, A.J

    2002-09-01

    This report documents the rate constants and associated activation energies for the reactions of the primary radical species, e{sub aq}{sup -}, {center_dot}OD and {center_dot}D, which are formed during the radiolysis of heavy water within the temperature range 20 to 250 {sup o}C. These heavy-water data have been compared with the corresponding information for light water. These kinetic data form part of the database that is required to model the aqueous radiation chemistry that occurs within the core of the heavy water cooled and moderated CANDU reactor. (author)

  10. DIGITALNA TOPOGRAFSKA KARTA 1:250 000 – PREMA NATO STANDARDIMA

    OpenAIRE

    Mirko Borisov

    2007-01-01

    U radu se iznose iskustva pri izradi i oblikovanju vojne topografske karte razmera 1: 250 000. Karta se izrađuje u Vojnogeografskom institutu, po NATO standardima i u digitalnom obliku. Iskustva drugih država u kreiranju vojnih topografsko-kartografskih sistema i karata mogu se uporediti sa našim. Postupci izrade i ažuriranja vojnih topografskih karata su informatički podržani uz veliki stepen automatizacije pojedinih faza njihove izrade i osavremenjavanja.

  11. A 250-GHz CARM [Cyclotron Auto Resonance Maser] oscillator experiment driven by an induction linac

    International Nuclear Information System (INIS)

    A 250-GHz Cyclotron Auto Resonance Maser (CARM) oscillator has been designed and constructed and will be tested using a 1-kA, 2-MeV electron beam produced by the induction linac at the Accelerator Research Center (ARC) facility of Lawrence Livermore National Laboratory (LLNL). The oscillator circuit was made to operate in the TE11 mode at ten times cutoff using waveguide Bragg reflectors to create an external cavity Q of 8000. Theory predicts cavity fill times of less than 30 ns (pulse length) and efficiencies approaching 20% is sufficiently low transverse electron velocity spreads are maintained (2%)

  12. A kinetic-phase transformation near 250 K in potassium tetrachlorozincate

    International Nuclear Information System (INIS)

    Raman-scattering experiments have been performed to study the successive phase transitions of K2ZnCl4 over the temperature range (100/600) K. The spectra provide the temperature dependence of the mode frequencies and linewidths for two different spatial configurations: a(bb) c and c(aa) b. Special emphasis is put upon a new phenomenon observed in the spectra around 250 K in the c*/3 superstructure. Its kinetic character is revealed by complementary DSC measurements carried out over the range (120/300) K. This phenomenon is interpreted as a progressive structural transformation which corresponds to a slow modification of the tetrahedron distortions. (orig.)

  13. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution

    DEFF Research Database (Denmark)

    Samuelsen, Camilla O; Baraznenok, Vera; Khorosjutina, Olga;

    2003-01-01

    In Saccharomyces cerevisiae Mediator, a subgroup of proteins (Srb8, Srb9, Srb10, and Srb11) form a module, which is involved in negative regulation of transcription. Homologues of Srb10 and Srb11 are found in some mammalian Mediator preparations, whereas no clear homologues have been reported for...... Srb8 and Srb9. Here, we identify a TRAP240/ARC250 homologue in Schizosaccharomyces pombe and demonstrate that this protein, spTrap240, is stably associated with a larger form of Mediator, which also contains conserved homologues of Srb8, Srb10, and Srb11. We find that spTrap240 and Sch. pombe Srb8 (sp...

  14. pUR 250 allows rapid chemical sequencing of both DNA strands of its inserts.

    OpenAIRE

    Rüther, U

    1982-01-01

    A multipurpose plasmid, pUR 250, has been constructed. It contains seven unique cloning sites (Hind III, Xba I, Sal I, Acc I, Hinc II, BamH I and EcoR I) in a small region of its lac Z gene part. Insertion of foreign DNA into the plasmid can be easily detected. Plasmid DNA isolated from a clone by a rapid method can be used to determine the DNA sequence of the insert from both ends directly without isolation of labeled fragment.

  15. High speed (<= 250 ps) high gain X-ray shutter camera

    International Nuclear Information System (INIS)

    A high speed X-ray shutter tube has been developed for laser induced plasma imaging. The limiting exposure time is in the 250 ps range and 5 images can be recorded on the same, laser shot, in order to provide a 5 spectral channel analysis of the plasma. A high light gain is obtained from a microchannel plate inserted in the 50Ω transmission line, which provide the adapted structure to reach such a time exposure. We present the main performances of this camera

  16. Dynamic nuclear polarization at 9 T using a novel 250 GHz gyrotron microwave source

    OpenAIRE

    Bajaj, V. S.; Farrar, C. T.; Hornstein, M.K.; Mastovsky, I.; Vieregg, J.; Bryant, J; Eléna, B.; Kreischer, K.E.; Temkin, R.J.; Griffin, R G

    2003-01-01

    In this communication, we report enhancements of nuclear spin polarization by dynamic nuclear polarization (DNP) in static and spinning solids at a magnetic field strength of 9 T (250 GHz for g = 2 electrons, 380 MHz for [superscript 1]H). In these experiments, [superscript 1]H enhancements of up to 170 ± 50 have been observed in 1-[superscript 13]C-glycine dispersed in a 60:40 glycerol/water matrix at temperatures of 20 K; in addition, we have observed significant enhancements in [superscrip...

  17. An investigation into the influence of female directors on audit effort: Evidence from FTSE 250

    OpenAIRE

    Li, Yue

    2013-01-01

    This study is conducted in order to detect if the female directors on board would have influence on the oversight function of the whole board and finally influence the audit fee. The motivation of this study is the increasing number of the female members in the workplace as well as the increasing number of female directors on board. This study focus on the UK market, so the data used in this paper is derived from FTSE 250 and the major methodology adopted in the empirical study is OLS regress...

  18. Alkaline electrolysis cell at high temperature and pressure of 250 °C and 42 bar

    DEFF Research Database (Denmark)

    Allebrod, Frank; Chatzichristodoulou, Christodoulos; Mogensen, Mogens Bjerg

    2013-01-01

    A new type of alkaline electrolysis cells with nickel foam based gas diffusion electrodes and KOH (aq) immobilized in mesoporous SrTiO3 has been developed and tested at temperatures and pressures up to 250 °C and 42 bar, respectively. Current densities of 1.0 A cm−2 have been measured at a cell...... voltage of 1.5 V without the use of expensive noble metal catalysts. High electrical efficiency and current density combined with relatively small production costs may lead to both reduced investment and operating costs for hydrogen and oxygen production....

  19. Radiation damage studies on STAR250 CMOS sensor at 300 keV for electron microscopy

    Science.gov (United States)

    Faruqi, A. R.; Henderson, R.; Holmes, J.

    2006-09-01

    There is a pressing need for better electronic detectors to replace film for recording high-resolution images using electron cryomicroscopy. Our previous work has shown that direct electron detection in CMOS sensors is promising in terms of resolution and efficiency at 120 keV [A.R. Faruqi, R. Henderson, M. Prydderch, R. Turchetta, P. Allport, A. Evans, Nucl. Instr. and Meth. 546 (2005) 170], but in addition, the detectors must not be damaged by the electron irradiation. We now present new measurements on the radiation tolerance of a 25 μm pitch CMOS active-pixel sensor, the STAR250, which was designed by FillFactory using radiation-hard technology for space applications. Our tests on the STAR250 aimed to establish the imaging performance at 300 keV following irradiation. The residual contrast, measured on shadow images of a 300 mesh grid, was >80% after corrections for increased dark current, following irradiation with up to 5×10 7 electrons/pixel (equivalent to 80,000 electron/μm 2). A CMOS sensor with this degree of radiation tolerance would survive a year of normal usage for low-dose electron cryomicroscopy, which is a very useful advance.

  20. Particle production in hadron-proton interactions at 250 GeV/c incident beam momentum

    International Nuclear Information System (INIS)

    In this thesis several characteristic properties are described of π+p, K+p and pp collisions at an incident beam momentum of 250 GeV/c, and compared to characteristics of other energy. The experiment has been performed in the European Hybrid Spectrometer (EHS) exposed to a tagged meson enriched beam. The rapid cycling bubble-chamber and the other detector elements which comprise EHS are described in Ch. 2. Events used for the analysis have been scanned, measured and merged with the electronic counter information. After the merge steps the data have been processed through a chain of reconstruction programs (Ch. 3). In Ch. 4 the multiplicity distributions and topological cross sections are presented. An introduction to the models (Monte Carlo programs) is given in Ch. 5. In Ch. 6 the characteristics of charged particle production in π+p, K+p and pp collisions at 250 GeV/c are presented. In Ch. 7 the forward π0 production is presented, a study of rho and omega resonance production in the forward hemisphere in Ch. 8. In Ch. 6, 7 and 8, the data are compared to predictions from the Monte Carlo programs described in Ch. 5. 117 refs.; 70 figs.; 23 tabs

  1. Microstructure and Hardness of T250 Maraging Steel in Heat Affected Zone

    Institute of Scientific and Technical Information of China (English)

    MO De-feng; HU Zheng-fei; CHEN Shu-juan; WANG Chun-xu; HE Guo-qiu

    2009-01-01

    Electron-beam (EB) welding was used in T250 maraging steel,microstructures of both base material and heat affected zone (HAZ) were investigated by optical microscopy (OM),scanning electron microscopy (SEM) and transmission electron microscopy (TEM),and microhardness was tested.The results showed that during EB welding,the HAZ of T250 maraging steel exhibited a continuous gradient structure.The microstructure of the entire HAZ,from fusion line,could be divided into four zones:fusion zone,overheated zone,transition zone,and hardened zone.The microhardness showed a distinct regularity in each area.The softest region was the fusion zone,whereas the hardest was the hardened zone.In the overheated zone,the hardness increased as the grain size decreased.Furthermore,in the transition zone,the hardness level dropped noticeably.The peak temperature during the thermal cycle had a great influence on the formation of reverted austenite and dissolution of the precipitated particles,which contributed a lot to the microstrueture and hardness of this material.

  2. Molecular gas kinematics within the central 250 pc of the Milky Way

    CERN Document Server

    Henshaw, J D; Kruijssen, J M D; Davies, B; Bally, J; Barnes, A; Battersby, C; Burton, M; Cunningham, M R; Dale, J E; Ginsburg, A; Immer, K; Jones, P A; Kendrew, S; Mills, E A C; Molinari, S; Moore, T J T; Ott, J; Pillai, T; Rathborne, J; Schilke, P; Schmiedeke, A; Testi, L; Walker, D; Walsh, A; Zhang, Q

    2016-01-01

    Using spectral-line observations of HNCO, N2H+, and HNC, we investigate the kinematics of dense gas in the central ~250 pc of the Galaxy. We present SCOUSE (Semi-automated multi-COmponent Universal Spectral-line fitting Engine), a line fitting algorithm designed to analyse large volumes of spectral-line data efficiently and systematically. Unlike techniques which do not account for complex line profiles, SCOUSE accurately describes the {l, b, v_LSR} distribution of CMZ gas, which is asymmetric about Sgr A* in both position and velocity. Velocity dispersions range from 2.6 km/s28. The gas is distributed throughout several "streams", with projected lengths ~100-250 pc. We link the streams to individual clouds and sub-regions, including Sgr C, the 20 and 50 km/s clouds, the dust ridge, and Sgr B2. Shell-like emission features can be explained by the projection of independent molecular clouds in Sgr C and the newly identified conical profile of Sgr B2 in {l ,b, v_LSR} space. These features have previously invoked...

  3. Temperature variation and its driving forces over the Antarctic coastal regions in the past 250 years

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    By comparing the oxygen isotopic temperatures recorded by many shallow ice cores fromthe coastal regions of Antarctica, this paper presents the special characteristics of the temperaturevariations over the Antarctic coastal regions in the past 50 years, 150 years and 250 years. In thepast 50 years, the isotopic temperatures recorded in the ice cores over different sites on the Antarcticcoastal regions differ greatly. For instance, although increasing isotopic temperatures have beenreported for many sites studied, many sites show decreasing trends, the regional regularity intemperature variations is still insignificant. In the past 150 years, the isotopic temperature trends inthe coastal regions of Antarctica show an alternate-distributing pattern. In the past 250 years, all theice cores from the coastal regions of Antarctica have recorded the so-called Little Ice Age (LIA). Theabove-mentioned spatial characteristics of the temperature variations over the Antarctic coastalregions are likely to reflect the impacts of the unique Southern Hemisphere atmospheric circulation,the Antarctic Circumpolar Wave (ACW) and the special terrain (such as the large drainage basins) onthe coastal regions of Antarctica. Furthermore, the impacting intensity of the unique SouthernHemisphere atmospheric circulation, the Antarctic Circumpolar Wave and the special terrain differs interms of the temporal scale of the temperature change.

  4. Dynamic nuclear polarization at 9 T using a novel 250 GHz gyrotron microwave source

    Science.gov (United States)

    Bajaj, V. S.; Farrar, C. T.; Hornstein, M. K.; Mastovsky, I.; Vieregg, J.; Bryant, J.; Eléna, B.; Kreischer, K. E.; Temkin, R. J.; Griffin, R. G.

    2011-12-01

    In this communication, we report enhancements of nuclear spin polarization by dynamic nuclear polarization (DNP) in static and spinning solids at a magnetic field strength of 9 T (250 GHz for g = 2 electrons, 380 MHz for 1H). In these experiments, 1H enhancements of up to 170 ± 50 have been observed in 1- 13C-glycine dispersed in a 60:40 glycerol/water matrix at temperatures of 20 K; in addition, we have observed significant enhancements in 15N spectra of unoriented pf1-bacteriophage. Finally, enhancements of ˜17 have been obtained in two-dimensional 13C- 13C chemical shift correlation spectra of the amino acid U- 13C, 15N-proline during magic angle spinning (MAS), demonstrating the stability of the DNP experiment for sustained acquisition and for quantitative experiments incorporating dipolar recoupling. In all cases, we have exploited the thermal mixing DNP mechanism with the nitroxide radical 4-amino-TEMPO as the paramagnetic dopant. These are the highest frequency DNP experiments performed to date and indicate that significant signal enhancements can be realized using the thermal mixing mechanism even at elevated magnetic fields. In large measure, this is due to the high microwave power output of the 250 GHz gyrotron oscillator used in these experiments.

  5. Development Status of Power Processing Unit for 250mN-Class Hall Thruster

    Science.gov (United States)

    Osuga, H.; Suzuki, K.; Ozaki, T.; Nakagawa, T.; Suga, I.; Tamida, T.; Akuzawa, Y.; Suzuki, H.; Soga, Y.; Furuichi, T.; Maki, S.; Matui, K.

    2008-09-01

    Institute for Unmanned Space Experiment Free Flyer (USEF) and Mitsubishi Electric Corporation (MELCO) are developing the next generation ion engine system under the sponsorship of Ministry of Economy, Trade and Industry (METI) within six years. The system requirement specifications are a thrust level of over 250mN and specific impulse of over 1500 sec with a less than 5kW electric power supply, and a lifetime of over 3,000 hours. These target specifications required the development of both a Hall Thruster and a Power Processing Unit (PPU). In the 2007 fiscal year, the PPU called Second Engineering Model (EM2) consist of all power supplies was a model for the Hall Thruster system. The EM2 PPU showed the discharge efficiency was over 96.2% for 250V and 350V at output power between 1.8kW to 4.5kW. And also the Hall Thruster could start up quickly and smoothly to control the discharge voltage, the inner magnet current, the outer magnet current and the xenon flow rate. This paper reports on the design and test results of the EM2 PPU.

  6. Neutron production for 250 MeV protons bombarding on thick grain-made tungsten target

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xueying; Zhang, Yanbin; Ma, Fei; Ju, Yongqin; Chen, Liang; Wang, Jianguo; Ge, Honglin [Chinese Academy of Sciences, Institute of Modern Physics, Lanzhou (China); Zhang, Hongbin; Li, Yanyan; Wan, Bo [Chinese Academy of Sciences, Institute of Modern Physics, Lanzhou (China); University of Chinese Academy of Sciences, Beijing (China)

    2015-08-15

    Neutron yield for 250 MeV protons incident on a tungsten target has been measured using the water bath method. The target was made of many randomly placed tungsten grains. Through analyzing the activity of Au foils, the neutron flux distribution in water was obtained. The neutrons slowing down process shows that the neutrons from tungsten have an average energy lower than neutrons from the lead target. The neutron yield was experimentally determined to be 2.02 ± 0.15 neutron/proton. Detailed simulation was also performed with the Geant4 toolkit. Comparison has been made with the experimentally derived neutron yield. It was found that, around 250 MeV, experimental results were described satisfactorily with a combination of high-energy spallation, low-energy neutron reaction and scattering. It was shown that the grain-packed target does not affect much the main neutronic properties, which are of crucial importance for the design of the spallation target. (orig.)

  7. Properties of compact 250 \\mu m emission and HII regions in M33 (HERM33ES)

    CERN Document Server

    Verley, S; Kramer, C; Xilouris, E M; Boquien, M; Calzetti, D; Combes, F; Buchbender, C; Braine, J; Quintana-Lacaci, G; Tabatabaei, F S; Lord, S; Israel, F; Stacey, G; van der Werf, P

    2010-01-01

    Within the framework of the HERM33ES Key Project, using the high resolution and sensitivity of the Herschel photometric data, we study the compact emission in the Local Group spiral galaxy M33 to investigate the nature of the compact SPIRE emission sources. We extracted a catalogue of sources at 250um in order to investigate the nature of this compact emission. Taking advantage of the unprecedented Herschel resolution at these wavelengths, we also focus on a more precise study of some striking Halpha shells in the northern part of the galaxy. We present a catalogue of 159 compact emission sources in M33 identified by SExtractor in the 250um SPIRE band that is the one that provides the best spatial resolution. We also measured fluxes at 24um and Halpha for those 159 extracted sources. The morphological study of the shells also benefits from a multiwavelength approach including Halpha, far-UV from GALEX, and infrared from both Spitzer IRAC 8um and MIPS 24um in order to make comparisons. For the 159 compact sour...

  8. First polarized proton collision at a beam energy of 250 GeV in RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Bai,M.; Ahrens, L.; Alekseev, I. G.; Alessi, J.; et al.

    2009-05-04

    After providing collisions of polarized protons at a beam energy of 100 GeV since 2001, the Relativistic Heavy Ion Collider (RHIC) at BNL had its first opportunity to collide polarized protons at its maximum beam energy of 250 GeV in the 2009 polarized proton operations. Equipped with two full Siberian snakes [1] in each ring, RHIC preserves polarization during acceleration from injection to 100 GeV with precise control of the betatron tunes and vertical orbit distortions. However, the strong intrinsic spin resonances beyond 100 GeV are more than two times stronger than those below 100 GeV, requiring much tighter tolerances on vertical orbit distortions and betatron tunes. With the currently achieved orbit correction and tune control, average polarizations of {approx_equal} 42% at top energy and average polarizations of {approx_equal} 55% at injection energy were achieved. Polarization measurements as a function of beam energy also indicated aU polarization losses occurred around three strong intrinsic resonances at 136 GeV, 199.3 GeV and 220.8 GeV Peak luminosity of 122 x 10{sup 30} cm{sup -2} s{sup -1} was also demonstrated. This paper presents the performance of the first RHIC 250 GeV operation and discusses the depolarization issues encountered during the run.

  9. Cooling system upgrading from 250 kW to 1 MW

    International Nuclear Information System (INIS)

    The Oregon State TRIGA reactor (OSTR) power capability was upgraded from 250 KW to 1 MW in 1969; however, funds were not available for simultaneous upgrading of the cooling system. Since then, the OSTR has been selectively operating at full power with the original 250 KW cooling system. After funds were made available in 1971 the construction on the new heat exchanger building began. The new cooling system was installed, equipment was checked out, corrections were made, and acceptance tests were run. In addition, several days were required to clean up the primary system water, since increased water flow (350 gpm) swirled 4 year's collection of sediment off the reactor tank bottom and into the primary system. Three interesting items have been noticed, which are apparently a result of the cooling system upgrading: (1) the radiation levels above the reactor tank have been reduced by a factor of 2 to 3, (2) a low resonance vibration in the reactor core occurs at 1 MW. The vibration is attributed to a combination of increased water turbulence and subcooled (surface) nucleate boiling, and (3) direct radiation levels from the demineralizer tank have increased approximately 8-fold. This resulted in a relocation of the tank and the use of supplemental shielding. Increased operating time at higher average power levels, plus disturbance of; sediment on the bottom of the reactor tank are believed to be the main sources of the higher radiation levels

  10. Clinicopathological analysis of 250 patients with early-stage gastric cancer%250例早期胃癌临床病理分析

    Institute of Scientific and Technical Information of China (English)

    钱建忠; 赵可; 李世兰; 徐洪明

    2010-01-01

    Objective To explore the factors associated with early diagnosis of gastric cancer.Methods Clinical data were retrospectively analyzed for 250 patients with early-stage gastric cancer (EGG) from 2005 to 2008, during which the concept of intra-epithelial neoplasia(IN) was adopted in our department. Results On preoperative endoscopic biopsy with pathological exam, there were 15 cases suspicious for cancer, 90 with high-grade IN(HGIN), and 15 gastric cancer. Postoperative pathological exam of the surgical specimen showed infiltrating early-stage cancer in 224 patients, of which 5(2.2%) were type Ⅰ(all were Tsm), 190 (84.8%) were type Ⅱ including Tm in 82 and Tsm in 108 patients, 29 were type Ⅲ (5 Tm and 24 Tsm). Twenty-six patients had non-infiltrating lesions(Tis).There were 184(73.6%)well-differentiated tumors, including 26 Tis, 58 Tm, and 100 Tsm. Lymphatic metastasis was identified in 21 patients, of which 2(2.3%) were Tin(all were poorly-differentiated) and 19 (13.9%) were Tsm. Lymphadenopathy was present in 15(7.9%) cases in type Ⅱ, and in 6(20.7%) in type Ⅲ. of the 90 cases with a preoperative diagnosis of HGIN, 24 were found to be Tis, 29 were Tin, and 37 were Tsm on postoperative pathological assessment. Conclusions Well-differentiation is the main histological type in EGC. The adoption of the concept of IN is associated with improved detection of EGC, which warrants further investigation.%目的 探讨进一步提高早期胃癌诊断水平的因素.方法 对2005-2008年间应用上皮内瘤变(IN)的概念诊断的250例早期胃癌患者的病理资料进行分析.结果 本组患者术前内镜活检诊断可疑癌15例,高级别上皮内瘤变(HGIN)90例,胃癌145例.术后病理诊断浸润型早期胃癌224例,其中Ⅰ型5例(2.2%),均为黏膜下癌(Tsm)患者;Ⅱ型190例(84.8%),有82例为黏膜内癌(Tm),108例为Tsm;Ⅲ型29例,5例Tm,24例Tsm.未浸润性病变(Tis)26例.以高分化为主要组织学类型者184例(73.6%),其中26

  11. Effect of JWH-250, JWH-073 and their interaction on "tetrad", sensorimotor, neurological and neurochemical responses in mice.

    Science.gov (United States)

    Ossato, Andrea; Canazza, Isabella; Trapella, Claudio; Vincenzi, Fabrizio; De Luca, Maria Antonietta; Rimondo, Claudia; Varani, Katia; Borea, Pier Andrea; Serpelloni, Giovanni; Marti, Matteo

    2016-06-01

    JWH-250 and JWH-073 are two synthetic cannabinoid agonists with nanomolar affinity at CB1 and CB2 receptors. They are illegally marketed within "herbal blend" for theirs psychoactive effects greater than those produced by Cannabis. Recently, we analyzed an "herbal" preparation containing a mixture of both JWH-250 and JWH-073. The present study was aimed at investigating the in vitro and in vivo pharmacological activity of JWH-250 and JWH-073 in male CD-1 mice. In vitro competition binding experiments performed on mouse and human CB1 and CB2 receptors revealed a nanomolar affinity and potency of the JWH-250 and JWH-073. In vivo studies showed that JWH-250 and JWH-073, administered separately, induced a marked hypothermia, increased pain threshold to both noxious mechanical and thermal stimuli, caused catalepsy, reduced motor activity, impaired sensorimotor responses (visual, acoustic and tactile), caused seizures, myoclonia, hyperreflexia and promote aggressiveness in mice. Moreover, microdialysis study in freely moving mice showed that systemic administration of JWH-250 and JWH-073 stimulated dopamine release in the nucleus accumbens in a dose-dependent manner. Behavioral, neurological and neurochemical effects were fully prevented by the selective CB1 receptor antagonist/inverse agonist AM 251. Co-administration of ineffective doses of JWH-250 and JWH-073 impaired visual sensorimotor responses, improved mechanical pain threshold and stimulated mesolimbic DA transmission in mice, living unchanged all other behavioral and physiological parameters. For the first time the present study demonstrates the overall pharmacological effects induced by the administration of JWH-250 and JWH-073 in mice and it reveals their potentially synergistic action suggesting that co-administration of different synthetic cannabinoids may potentiate the detrimental effects of individual compounds increasing their dangerousness and abuse potential. PMID:26780169

  12. 基于PLC的XS-ZY250A注塑机控制系统设计

    Institute of Scientific and Technical Information of China (English)

    魏强

    2010-01-01

    为改善注塑机传统电气控制存在的局限性和不足,采用西门子S7-300型系列PLC对XS-ZY250A普通卧式注塑机控制系统进行改造.阐述了PLC控制系统程序设计,给出了XS-ZY250A注塑机的PLC控制梯形图.

  13. Estimating wide range Total Suspended Solids concentrations from MODIS 250-m imageries: An improved method

    Science.gov (United States)

    Chen, Shuisen; Han, Liusheng; Chen, Xiuzhi; Li, Dan; Sun, Lin; Li, Yong

    2015-01-01

    The objective of this study was to evaluate the performance of moderate resolution imaging spectroradiometer (MODIS) 250 m based TSS (Total Suspended Solids) retrieval model for developing the model of wide-range TSS concentrations. Using field spectral and TSS data (5.8-577.2 mg/l) collected from estuary and coast of China, we calibrated (N = 40) and validated (N = 20) the 6 TSS retrieval models in forms of single band (B1 or B2), difference of the two bands, sediment index, band ratio and log-ratio by the least-squares technique. Results showed that the quadratic model of log-ratio is of the best accuracy (Calibration: R2 = 0.752, N = 40. Validation: TSS > 31 mg/l, RMSE = 37.9 mg/l, N = 12; TSS ⩽ 31mg /l, RMSE = 3.25 mg/l, N = 8). We also found that the spectral log-ratio values increased with the increasing of TSS when TSS 31 mg/l. The findings of quadratic curve vertex (log-ratio: ∼1.58) in the proposed TSS model indicated that the spectral log-ratio may be sensitive to TSS of both low and high concentrations. We further applied the preferred model to retrieve TSS concentration from the MODIS 250-m images in turbid estuarial and clear coastal waters, and obtained a good mapping accuracy from the result (TSS > 31 mg/l: RMSE = 38.6 mg/l, MRE = 24.7%, N = 17; TSS ⩽ 31mg /l : RMSE = 2.1 mg/l, MRE = 19.5%, N = 11). The vertex-based methodology of TSS model developed in the study is applicable in mapping TSS concentrations that are of a wide range variation in estuarine and coastal water bodies based on MODIS 250-m image, and as well to maximize its application potential due to high imaging frequency (two times during daytime) and appropriate space resolution of MODIS images. Therefore, the method can be used to detect the high temporal variability of TSS during tidal cycle. As such, the application of MODIS-water quality detection technology can be extended to coastal sediment movement.

  14. Design and development of collector for C-band 250 kW CW Klystron

    International Nuclear Information System (INIS)

    The paper presents the design and development of collector for C-band 250 kW high power klystron. The design criteria for the collector assembly is selection of material, vacuum and high temperature compatibility, proper electron beam dispersion, minimum back scattering of electrons and thermal design for proper cooling at high power dissipation. All these aspects have been discussed for collector development in details. The collector has been designed in TRAK and then beam propagation has been analyzed in MAGIC 2D software. The thermal simulation has been done using ANSYS 11.0 (multi-physics). The outer surface of the collector has been grooved to facilitate its proper cooling. Design results are presented for water cooling with different flow rates and channel dimensions. OFHC copper material is chosen for collector which is suitable for vacuum and hydrogen brazing operations and good thermal properties for efficient cooling.

  15. A 250 GHz gyrotron with a 3 GHz tuning bandwidth for dynamic nuclear polarization.

    Science.gov (United States)

    Barnes, Alexander B; Nanni, Emilio A; Herzfeld, Judith; Griffin, Robert G; Temkin, Richard J

    2012-08-01

    We describe the design and implementation of a novel tunable 250 GHz gyrotron oscillator with >10 W output power over most of a 3 GHz band and >35 W peak power. The tuning bandwidth and power are sufficient to generate a >1 MHz nutation frequency across the entire nitroxide EPR lineshape for cross effect DNP, as well as to excite solid effect transitions utilizing other radicals, without the need for sweeping the NMR magnetic field. Substantially improved tunability is achieved by implementing a long (23 mm) interaction cavity that can excite higher order axial modes by changing either the magnetic field of the gyrotron or the cathode potential. This interaction cavity excites the rotating TE(₅,₂,q) mode, and an internal mode converter outputs a high-quality microwave beam with >94% Gaussian content. The gyrotron was integrated into a DNP spectrometer, resulting in a measured DNP enhancement of 54 on the membrane protein bacteriorhodopsin. PMID:22743211

  16. A 250 GHz gyrotron with a 3 GHz tuning bandwidth for dynamic nuclear polarization

    Science.gov (United States)

    Barnes, Alexander B.; Nanni, Emilio A.; Herzfeld, Judith; Griffin, Robert G.; Temkin, Richard J.

    2012-08-01

    We describe the design and implementation of a novel tunable 250 GHz gyrotron oscillator with >10 W output power over most of a 3 GHz band and >35 W peak power. The tuning bandwidth and power are sufficient to generate a >1 MHz nutation frequency across the entire nitroxide EPR lineshape for cross effect DNP, as well as to excite solid effect transitions utilizing other radicals, without the need for sweeping the NMR magnetic field. Substantially improved tunability is achieved by implementing a long (23 mm) interaction cavity that can excite higher order axial modes by changing either the magnetic field of the gyrotron or the cathode potential. This interaction cavity excites the rotating TE5,2,q mode, and an internal mode converter outputs a high-quality microwave beam with >94% Gaussian content. The gyrotron was integrated into a DNP spectrometer, resulting in a measured DNP enhancement of 54 on the membrane protein bacteriorhodopsin.

  17. Circulating fluidized bed combustion ash characterization. The case of the Provence 250 MW unit

    Energy Technology Data Exchange (ETDEWEB)

    Lecuyer, I.; Leduc, M. [Electricite de France (EDF), 78 - Chatou (France). Direction des Etudes et Recherches; Lefevre, R.; Ausset, P. [Paris-12 Univ., Creteil (France). Lab. Interuniversitaire des Systemes Atmospheriques

    1997-05-01

    The Provence 250 MW Circulating Fluidized Bed Combustion Unit (Gardanne, France) is burning a high sulfur (2 to 4%), high ash content (30%) local lignite. This peculiar fuel already contains about 15% of CaO which allows it to capture the sulfur dioxide in situ without adding any complementary sorbent. The ash chemical composition (bed ash and ESP ash) that reflects the particularities of the coal is presented. SEM and DRX observations confirm the presence of anhydrite CaSO{sub 4}, lime, CaS, quartz and traces of hematite. Most of particles are roughly-shaped but microspheres can also be detected in fly ash. The very high sulfate content may be worrying for the environment in disposals. Hardened samples do not seem to retain compounds from leaching: high quantities of calcium and sulfates are still leached from these crushed samples. (author) 10 refs.

  18. Three-dimensional magnetic cloak working from DC to 250 kHz

    CERN Document Server

    Zhu, Jianfei; Liu, Yichao; Yin, Ge; Yuan, Jun; He, Sailing; Ma, Yungui

    2015-01-01

    Invisible cloaking is one of major outcomes of the metamaterial research, but the practical potential, in particular for high frequencies (e.g., microwave to visible light), is fatally challenged by the complex material properties they usually demand. On the other hand, it will be advantageous and also technologically instrumental to design cloaking devices for applications at low frequencies where electromagnetic components are favorably uncoupled. In this work, we vastly develop the bilayer approach to create a three-dimensional magnetic cloak able to work in both static and dynamic fields. Under the quasi-static approximation, we demonstrate a perfect magnetic cloaking device with a large frequency band from zero to 250 kHz. The practical potential of our device is experimentally verified by using a commercial metal detector, which may lead us to having a real cloaking application where the dynamic magnetic field can be manipulated in desired ways.

  19. Structure function scaling in a Reλ = 250 turbulent mixing layer

    KAUST Repository

    Attili, Antonio

    2011-12-22

    A highly resolved Direct Numerical Simulation of a spatially developing turbulent mixing layer is presented. In the fully developed region, the flow achieves a turbulent Reynolds number Reλ = 250, high enough for a clear separation between large and dissipative scales, so for the presence of an inertial range. Structure functions have been calculated in the self-similar region using velocity time series and Taylor\\'s frozen turbulence hypothesis. The Extended Self-Similarity (ESS) concept has been employed to evaluate relative scaling exponents. A wide range of scales with scaling exponents and intermittency levels equal to homogeneous isotropic turbulence has been identified. Moreover an additional scaling range exists for larger scales; it is characterized by smaller exponents, similar to the values reported in the literature for flows with strong shear.

  20. Preequilibrium particle emission in 250 MeV {sup 16}O + {sup 116}Sn reaction

    Energy Technology Data Exchange (ETDEWEB)

    Barlini, S.; Kravchuk, V.L.; Gramegna, F. [INFN, Laboratori Nazionali di Legnaro Padova (Italy)] (and others)

    2005-07-01

    A certain progress in understanding the phenomenon of the Preequilibrium (fast) light charged particle and neutron Emission (PE) was achieved in the last two decades. However, there is a strong need to study systematically the dependence of the PE emission on the reaction mass asymmetry and the projectile energy. In the present work we present the results on the PE proton and alpha-particle multiplicities and the total energy loss of the composite system formed in fusion reaction E{sub b}eam=250 MeV (15.6 MeV/u) {sup 16}O + {sup 116}Sn. The experiment was performed at the Legnaro National Laboratory using a 1 ns (FWHM) pulsed beam provided by the TANDEM-ALPI acceleration system.

  1. Fabrication of 250-nm-hole arrays in glass and fused silica by UV laser ablation

    Science.gov (United States)

    Karstens, R.; Gödecke, A.; Prießner, A.; Ihlemann, J.

    2016-09-01

    Parallel nanohole drilling in glass using an ArF excimer laser (193 nm) is demonstrated. For the first time, hole arrays with 500 nm pitch and individual holes with 250 nm diameter and more than 100 nm depth are fabricated by phase mask imaging using a Schwarzschild objective. Holes in soda lime glass are drilled by direct ablation; fused silica is processed by depositing a SiOx-film on SiO2, patterning the SiOx by ablation, and finally oxidizing the remaining SiOx to SiO2. Thermally induced ordered dewetting of noble metal films deposited on such templates may be used for the fabrication of plasmonic devices.

  2. Evidence for general instability of past climate from a 250-KYR ice-core record

    DEFF Research Database (Denmark)

    Johnsen, Sigfus Johann; Clausen, Henrik Brink; Dahl-Jensen, Dorthe;

    1993-01-01

    decades. Here we present a detailed stable-isotope record for the full length of the Greenland Ice-core Project Summit ice core, extending over the past 250 kyr according to a calculated timescale. We find that climate instability was not confined to the last glaciation, but appears also to have been...... results1,2 from two ice cores drilled in central Greenland have revealed large, abrupt climate changes of at least regional extent during the late stages of the last glaciation, suggesting that climate in the North Atlantic region is able to reorganize itself rapidly, perhaps even within a few...... interglacial seems to have lasted longer than is implied by the deep-sea SPECMAP record4, in agreement with other land-based observations5,6. We suggest that climate instability in the early part of the last interglacial may have delayed the melting of the Saalean ice sheets in America and Eurasia, perhaps...

  3. GaN pnp bipolar junction transistors operated to 250 C

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, A.P.; Dang, G.; Ren, F.; Han, J.; Monier, C.; Baca, A.G.; Cao, X.A.; Cho, H.; Abernathy, C.R.; Pearton, S.J.

    2000-01-03

    The authors report on the dc performance of the first GaN pnp bipolar junction transistor. The structure was grown by MOCVD on c-plane sapphire substrates and mesas formed by low damage Inductively Coupled Plasma etching with a Cl{sub 2}/Ar chemistry. The dc characteristics were measured up to V{sub BC} of 65 V in common base mode and at temperatures up to 250 C. Under all conditions, I{sub C} {approximately} I{sub E}, indicating higher emitter injection efficiency. The offset voltage was {le} 2 V and devices were operated up to power densities of 40kW{center{underscore}dot}cm{sup {minus}2}.

  4. Familiar words capture the attention of 11-month-olds in less than 250 ms.

    Science.gov (United States)

    Thierry, Guillaume; Vihman, Marilyn; Roberts, Mark

    2003-12-19

    The capacity of human infants to discriminate contrasting speech sounds specializes to the native language by the end of the first year of life, when the first signs of word recognition have also been found, using behavioural measures. The extent of voluntary attentional involvement in such word recognition has not been explored, however, nor do we know what its neural time-course may be. Here we demonstrate that 11-month-old children shift their attention automatically to familiar words within 250 ms of presentation onset by measuring event-related potentials elicited by familiar and unfamiliar words. A significant modulation of the first negative peak (N200), known to index implicit change detection in adults, was induced by word familiarity in the infants.

  5. Last 250 years climate reconstruction inferred from geothermal measurements in the Czech Republic

    Science.gov (United States)

    Bodri, L.; Čermák, V.

    1998-06-01

    The subsurface of the Earth has a certain capability to remember what has happened on its surface tens to hundreds of years ago. Ground surface temperature (GST) history, reflecting past climate conditions, can be evaluated by analysing the excursions left on the present-day temperature-depth distribution measured by precise temperature loggings in the boreholes. Temperature logs from fifteen selected holes were inverted into GST histories to assess the corresponding climatic changes. These temperature records generally represent typical conditions existing on the territory of the Czech Republic. In combination with the GST reconstructions from our previous works, these data were used to assess the regional pattern of the last 250-year climatic change. The GSTs were obtained by applying the generalized least-squares inversion method [Jackson, D.D., 1972. Interpretation of inaccurate, insufficient and inconsistent data. Geophys. J. R. Astron. Soc. 28, 97-109], whereby the additional information on interdependence of both measured data and climate changes can be incorporated into the model in the form of covariance matrices. Three main episodes can be distinguished in the last 250 years: a warm period between 1790 and 1830, a slightly colder period in 1940-1960, and a general warming with the average rates of 0.01-0.03 K/year since then. The geographical distribution of the recent warming rate may indicate an impact of human activities. The verification of the GST assessment was accomplished by the independent past climate reconstructions gained by the use of historical sources and instrumental records.

  6. Snow Cover Maps from MODIS Images at 250 m Resolution, Part 2: Validation

    Directory of Open Access Journals (Sweden)

    Marc Zebisch

    2013-03-01

    Full Text Available The performance of a new algorithm for binary snow cover monitoring based on Moderate Resolution Imaging Spectroradiometer (MODIS satellite images at 250 m resolution is validated using snow cover maps (SCA based on Landsat 7 ETM+ images and in situ snow depth measurements from ground stations in selected test sites in Central Europe. The advantages of the proposed algorithm are the improved ground resolution of 250 m and the near real-time availability with respect to the 500 m standard National Aeronautics and Space Administration (NASA MODIS snow products (MOD10 and MYD10. It allows a more accurate snow cover monitoring at a local scale, especially in mountainous areas characterized by large landscape heterogeneity. The near real-time delivery makes the product valuable as input for hydrological models, e.g., for flood forecast. A comparison to sixteen snow cover maps derived from Landsat ETM/ETM+ showed an overall accuracy of 88.1%, which increases to 93.6% in areas outside of forests. A comparison of the SCA derived from the proposed algorithm with standard MODIS products, MYD10 and MOD10, indicates an agreement of around 85.4% with major discrepancies in forested areas. The validation of MODIS snow cover maps with 148 in situ snow depth measurements shows an accuracy ranging from 94% to around 82%, where the lowest accuracies is found in very rugged terrain restricted to in situ stations along north facing slopes, which lie in shadow in winter during the early morning acquisition.

  7. VIABILITAS DAN STABILITAS Lactobacillus Plantarum Mut7 FNCC 250 YANG DISUPLEMENTASIKAN DALAM SARI BUAH PEPAYA-NANAS SELAMA PENYIMPANAN [Viability and Stability of Lactobacillus Plantarum Mut 7 FNCC 250 Suplemented in Papaya-Pineapple Juice During Storage

    Directory of Open Access Journals (Sweden)

    Sri Hartati1

    2003-08-01

    Full Text Available Lactobacillus plantarum Mut7 FNCC 250 is an indigenous bacterium isolated from fermented food (“gatot” and a potential agent to reduce cholesterol. Study the on aplication of the bacterium as probiotic agent to food stuff is needed. The purpose of the study was to prepare formula of papaya-pineapple juice as probiotic carrier and to study the viability and capability of Lactobacillus plantarum Mut7 FNCC 250 to assimilate cholesterol during three months storage. Fruits juice was prepared with different formula and organoleptically tested. Selected juice formula was supplemented with Lactobacillus plantarum Mut7 FNCC 250 and stored in cool room (4-5 oC. During three month storage, the value of pH the product, cell viability and ability to assimilate cholesterol were evaluated. The result indicated that acceptable formula was papaya juice added with 25 % pineapple. Viability of Lactobacillus plantarum Mut7 FNCC 250 supplemented in papaya- pineapple juice was stable (decrease of < 1 log cycle, while the pH of the juice decreased after 3 month storage. The ability of Lactobacillus plantarum Mut7 FNCC 250 to assimilate cholesterol was stable within 2 months storage, but decreased after 3 months.

  8. 250t/50t/10t精确吊装用桥式起重机的设计%Design of 250 t/50 t/10 t overhead travelling crane for accurate hoisting

    Institute of Scientific and Technical Information of China (English)

    王海涛; 潘彦宏

    2012-01-01

    介绍了安装于印度尼西亚某水电站厂房内的精确吊装用250 t/50 t/10 t桥式起重机性能、控制系统特点及其设计思路,指出了变频器选配要点.%This paper describes the performance, control system characteristics and design ideas of accurate hoisting 250t/50t/10t overhead travelling crane installed in the plant of the hydropower station in Indonesia, The key points for selecting and matching of frequency converters are also put forward in the paper.

  9. Influence of electroporation on immunogenicity of the DNA vaccine pVAX-tG250FcGB%电穿孔技术对DNA疫苗pVAX-tG250FcGB免疫效果的影响

    Institute of Scientific and Technical Information of China (English)

    肖毅; 于继云; 高昆; 杨勇; 阎瑾琦; 张亮; 王宇; 徐元基; 田仁礼; 杜芝燕

    2013-01-01

    Objective To investigate the influence of electroporation on the immunogenicity of the DNA vaccine pVAX-tG250FcGB. Methods The DNA vaccine pVAX-tG250FcGB was constructed by inserting the coding gene of tG250 fusion genes into the expression vector pVAX. The DNA vaccine was delivered in BALB/c mouse by electroporation or intramuscular injection, and the induced antigen specific immune responses were compared. Results The vaccine delivered by electroporation and intramuscular injection both induced immune responses in BALB/c mouse, but electroporation produced an obviously stronger effect than intramuscular injection. Conclusion Electroporation-mediated DNA vaccine delivery can produce strong immune response in mice and is an effective means for studying the immunogenic effect of DNA vaccine pVAX-tG250FcGB.%目的:探讨应用电穿孔技术对DNA疫苗pVAX-tG250FcGB免疫效果的影响。方法构建肾癌DNA疫苗pVAX-tG250FcGB,通过体内电穿孔技术或普通肌肉注射途径,将DNA疫苗导入到BALB/c小鼠体内,探讨电穿孔免疫途径诱导抗原特异性免疫应答的效果。结果电穿孔技术或普通肌肉注射均能在小鼠体内诱导出抗原特异性的体液免疫应答和细胞免疫应答,电穿孔技术的免疫效果明显优于普通肌肉注射途径。结论电穿孔技术介导的DNA疫苗pVAX-tG250FcGB免疫具有较强的诱导免疫应答的能力,是研究DNA疫苗pVAX-tG250FcGB免疫效果的一种有效途径。

  10. Corrosion mechanisms of the AlFeNi aluminium alloy by water up to 250 deg

    International Nuclear Information System (INIS)

    Full text of publication follows: The AlFeNi aluminium alloy (1%Fe, 1%Ni, 1%Mg) will be used as nuclear fuel cladding in the Jules Horowitz research reactor. A better understanding of the corrosion mechanisms of this alloy in water is necessary to predict correctly the corrosion rate and the oxide thickness on the fuel plates. Corrosion tests in water at an average pH of 6.9 were hence performed on this alloy in static conditions at 70, 165 and 250 C, and in dynamic conditions at 70 C. The hydroxide film obtained on the samples corroded in autoclaves or at the slow flow rates is composed of two main layers: a dense and amorphous inner layer which grows by anionic diffusion and a porous crystalline outer layer which develops by cationic diffusion followed by a dissolution-precipitation process. The ratio of the amorphous oxide thickness to the corroded metal thickness decreases with corrosion time, thus indicating an increasing density of the amorphous oxide. Consequently, the diffusion through the inner oxide layer decreases drastically with corrosion time. The inner oxide thickness evolution is well described by a cationic diffusion model, with an apparent cationic diffusion coefficient decreasing exponentially with time. A comparison of the corrosion scales obtained in water and in vapour at 250 C showed that in the vapour, the outer precipitation oxide layer does not develop, and the inner oxide thickness is much lower. These results suggest that the anionic diffusion which controls the corrosion rate at the metal interface is coupled with the cationic diffusion and dissolution rate. The hydraulic conditions play therefore a dominant role in the corrosion rate. During dynamic experiments in once-through reactors at 70 C, the cationic release in the leaching water was measured at different times. Two leaching flow rates were used: 100 and 200 ml/h. After the first 3 hours, the aluminium and magnesium release follow a parabolic evolution, characteristic of a

  11. Crop Dominance Mapping with IRS-P6 and MODIS 250-m Time Series Data

    Directory of Open Access Journals (Sweden)

    Murali Krishna Gumma

    2014-04-01

    Full Text Available This paper describes an approach to accurately separate out and quantify crop dominance areas in the major command area in the Krishna River Basin. Classification was performed using IRS-P6 (Indian Remote Sensing Satellite, series P6 and MODIS eight-day time series remote sensing images with a spatial resolution of 23.6 m, 250 m for the year 2005. Temporal variations in the NDVI (Normalized Difference Vegetation Index pattern obtained in crop dominance classes enables a demarcation between long duration crops and short duration crops. The NDVI pattern was found to be more consistent in long duration crops than in short duration crops due to the continuity of the water supply. Surface water availability, on the other hand, was dependent on canal water release, which affected the time of crop sowing and growth stages, which was, in turn, reflected in the NDVI pattern. The identified crop-wise classes were tested and verified using ground-truth data and state-level census data. The accuracy assessment was performed based on ground-truth data through the error matrix method, with accuracies from 67% to 100% for individual crop dominance classes, with an overall accuracy of 79% for all classes. The derived major crop land areas were highly correlated with the sub-national statistics with R2 values of 87% at the mandal (sub-district level for 2005–2006. These results suggest that the methods, approaches, algorithms and datasets used in this study are ideal for rapid, accurate and large-scale mapping of paddy rice, as well as for generating their statistics over large areas. This study demonstrates that IRS-P6 23.6-m one-time data fusion with MODIS 250-m time series data is very useful for identifying crop type, the source of irrigation water and, in the case of surface water irrigation, the way in which it is applied. The results from this study have assisted in improving surface water and groundwater irrigated areas of the command area and also

  12. Sodium trimetaphosphate enhances the effect of 250 p.p.m. fluoride toothpaste against enamel demineralization in vitro.

    Science.gov (United States)

    Missel, Emilene M C; Cunha, Robson F; Vieira, Ana E M; Cruz, Nathália V S; Castilho, Flavia C N; Delbem, Alberto C B

    2016-08-01

    This in vitro study investigated the effect of sodium trimetaphosphate (TMP), added to toothpaste containing 250 p.p.m. fluoride, on enamel demineralization. Bovine enamel blocks (n = 96) were subjected to five pH cycles over a 7-d period and treatment with suspensions of toothpastes containing 0, 250, 500, and 1,100 p.p.m. fluoride (as sodium fluoride), as well as with 250 p.p.m. fluoride containing TMP at 0.25, 0.5, 1.0, and 3.0%. Treatment with toothpaste suspensions was performed under agitation twice a day, for 1 min. Surface and cross-sectional hardness, and fluoride firmly bound to enamel, were quantified. Data were subjected to one-way anova, followed by Tukey's test. Low-fluoride toothpastes containing TMP at 0.25-1.0% resulted in enamel mineral loss similar to that seen for the toothpaste containing 1,100 p.p.m. fluoride. Also, the addition of TMP to the toothpaste containing 250 p.p.m. fluoride promoted enamel fluoride concentrations similar to those obtained for the 500 p.p.m. fluoride group. The toothpaste containing 250 p.p.m. fluoride and 0.25% TMP led to the lowest mineral loss among all groups. It was concluded that the addition of as little as 0.25% TMP to a toothpaste containing 250 p.p.m. fluoride can reduce enamel demineralization to levels similar to those seen for a conventional toothpaste containing 1,100 p.p.m. fluoride, in vitro. PMID:27198971

  13. Paediatric Tuberculosis at a Referral Hospital in Istanbul: Analysis of 250 Cases.

    Science.gov (United States)

    Turel, Ozden; Kazanci, Selcen; Gonen, Ismail; Aydogmus, Cigdem; Karaoglan, Emel; Siraneci, Rengin

    2016-01-01

    Background. Tuberculosis (TB) still remains a growing public health problem globally. TB in children is often diagnosed clinically. Methods. We conducted a retrospective chart review of children with TB from November 2004 through December 2010 to determine the appropriateness of using contact history and diagnostic testing. Results. A total of 250 children with TB were identified. One hundred and sixty-two children had only pulmonary disease while 39 had features of both extrapulmonary and pulmonary TB. Mean age was 7.8 years. Thirty-six patients had known contacts. The index case/cases were first-degree relatives in 75%. Sixteen patients who were symptomless were yielded by contact investigation of newly identified TB cases. Tuberculin skin test positivity was 53.3%. Acid-fast bacilli smear positivity was 13.1%, and culture positivity was 18.7%. Twenty-six patients had histopathology of nonrespiratory specimens (lymph nodes and other tissues) showing granulomatous inflammation and caseous necrosis consistent with TB. Conclusions. Presence of contact history directed us to search for TB in children with nonspecific symptoms even if physical examinations were normal. Some children who were close contacts to TB cases were identified to have TB before development of symptoms.

  14. Neanderthal use of fish, mammals, birds, starchy plants and wood 125-250,000 years ago.

    Directory of Open Access Journals (Sweden)

    Bruce L Hardy

    Full Text Available Neanderthals are most often portrayed as big game hunters who derived the vast majority of their diet from large terrestrial herbivores while birds, fish and plants are seen as relatively unimportant or beyond the capabilities of Neanderthals. Although evidence for exploitation of other resources (small mammals, birds, fish, shellfish, and plants has been found at certain Neanderthal sites, these are typically dismissed as unusual exceptions. The general view suggests that Neanderthal diet may broaden with time, but that this only occurs sometime after 50,000 years ago. We present evidence, in the form of lithic residue and use-wear analyses, for an example of a broad-based subsistence for Neanderthals at the site of Payre, Ardèche, France (beginning of MIS 5/end of MIS 6 to beginning of MIS 7/end of MIS 8; approximately 125-250,000 years ago. In addition to large terrestrial herbivores, Neanderthals at Payre also exploited starchy plants, birds, and fish. These results demonstrate a varied subsistence already in place with early Neanderthals and suggest that our ideas of Neanderthal subsistence are biased by our dependence on the zooarchaeological record and a deep-seated intellectual emphasis on big game hunting.

  15. Magnetic fields and beam optics studies of a 250 MeV superconducting proton radiotherapy cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong-Won [Research Institute and Hospital, National Cancer Center, 809 Madu-dong, Koyang, Kyonggi (Korea, Republic of)], E-mail: jwkim@ncc.re.kr

    2007-11-21

    A 250 MeV superconducting cyclotron for the proton radiation therapy was designed at the Michigan State University (MSU) for use at the Paul Scherrer Institut. This work was based on the conceptual design carried out at the MSU in 1994. The previous design was refined to finalize the magnet configuration and to optimally arrange cyclotron elements for the actual construction. The spiral angle of the pole was reduced, the new hill-edges and valley shims being introduced. The magnetic fields were highly isochronized using a least square fitting routine involving a schematic shimming scheme. The resulting reference field was adequate for the elaborate study of beam optics. The optics simulation predicted that extraction efficiency of above 80% was achievable for a beam with the initial phase width of 20{sup o}. The vertical deflector was investigated located in the central region to control the beam intensity with tracking of beam phase spaces. Some measurement results for the constructed cyclotron were found in a good agreement with those of the optics study.

  16. Integrated tests of a high speed VXS switch card and 250 MSPS flash ADCs

    Energy Technology Data Exchange (ETDEWEB)

    H. Dong, C. Cuevas, D. Curry, E. Jastrzembski, F. Barbosa, J. Wilson, M. Taylor, B. Raydo

    2008-01-01

    High trigger rate nuclear physics experiments proposed for the 12 GeV upgrade at the Thomas Jefferson National Accelerator Facility create a need for new high speed digital systems for energy summing. Signals from electronic detectors will be captured with the Jefferson Lab FADC module, which collects and processes data from 16 charged particle sensors with 10 or 12 bit resolution at 250 MHz sample rate. Up to sixteen FADC modules transfer energy information to a central energy summing module for each readout crate. The sums from the crates are combined to form a global energy sum that is used to trigger data readout for all modules. The Energy Sum module and FADC modules have been designed using the VITA-41 VME64 switched serial (VXS) standard. The VITA- 41 standard defines payload and switch slot module functions, and offers an elegant engineered solution for Multi-Gigabit serial transmission on a standard VITA-41 backplane. The Jefferson Lab Energy Sum module receives data serially at a rate of up to 6 Giga-bits per second from the FADC modules. Both FADC and Energy Sum modules have been designed and assembled and this paper describes the integrated tests using both high speed modules in unison

  17. MUSE-ings on AM1354-250: Collisions, Shocks and Rings

    CERN Document Server

    Conn, Blair C; Smith, Rory; Candlish, Graeme N

    2015-01-01

    We present MUSE observations of AM1354-250, confirming its status as a collisional ring galaxy which has recently undergone an interaction, creating its distinctive shape. We analyse the stellar and gaseous emission throughout the galaxy finding direct evidence that the gaseous ring is expanding with a velocity of $\\sim$70km.s$^{-1}$ and that star formation is occurring primarily in HII regions associated with the ring. This star formation activity is likely triggered by the interaction. We find evidence for several excitation mechanisms in the gas, including emission consistent with shocked gas in the expanding ring and a region of LINER-like emission in the central core of the galaxy. Evidence of kinematic disturbance in both the stars and gas, possibly also triggered by the interaction, can be seen in all of the velocity maps. The ring galaxy retains weak spiral structure, strongly suggesting the progenitor galaxy was a massive spiral prior to the collision with its companion an estimated $140 \\pm 12$ Myr ...

  18. MUSE-ings on AM1354-250: Collisions, Shocks, and Rings

    Science.gov (United States)

    Conn, Blair C.; Fogarty, L. M. R.; Smith, Rory; Candlish, Graeme N.

    2016-03-01

    We present Multi Unit Spectroscopic Explorer observations of AM1354-250, confirming its status as a collisional ring galaxy that has recently undergone an interaction, creating its distinctive shape. We analyze the stellar and gaseous emission throughout the galaxy finding direct evidence that the gaseous ring is expanding with a velocity of ˜70 km s-1 and that star formation is occurring primarily in H ii regions associated with the ring. This star formation activity is likely triggered by this interaction. We find evidence for several excitation mechanisms in the gas, including emission consistent with shocked gas in the expanding ring and a region of LINER-like emission in the central core of the galaxy. Evidence of kinematic disturbance in both the stars and gas, possibly also triggered by the interaction, can be seen in all of the velocity maps. The ring galaxy retains a weak spiral structure, strongly suggesting the progenitor galaxy was a massive spiral prior to the collision with its companion an estimated 140 ± 12 Myr ago.

  19. [Jonathan Swift's asylum in Dublin--Ireland's introduction to institutional psychiatry 250 years ago].

    Science.gov (United States)

    Reuber, M

    1995-09-01

    250 years ago, the satirical writer and clergyman Jonathan Swift from Dublin (1667-1745) founded the first Irish lunatic asylum. Rejecting the theories put forward by the English philosopher Thomas Hobbes and the doctor Thomas Willis, he was influenced by the ideas of the Scottish doctor and the "enlightened" thinker John Locke. Swift's St. Patrick's Hospital did not, however, realise a new philosophical concept: architecture and therapeutic approach of the new institution were clearly modelled on the much older Hospital of St. Mary of Bethlehem ( = Bedlam). Despite its conservative conceptual basis, the first institution dedicated to the mentally ill and intellectually subnormal in Ireland became a starting point for the apparantly unstoppable expansion of the, at one time, most comprehensive asylum system in the world. After Swift's Hospital had been enlarged twice at the tax-payers' expense (1778, 1793), the administration decided to relieve the institution by erecting the Richmond Asylum (1810), the first public asylum in Ireland. When this establishment also became overcrowded, in 1817, legislation was passed which led to the establishment of the oldest system of public asylums in Europe.

  20. 1:250,000-scale Hydrologic Units of the United States

    Science.gov (United States)

    Steeves, Peter; Nebert, Douglas

    1994-01-01

    The Geographic Information Retrieval and Analysis System (GIRAS) was developed in the mid 70s to put into digital form a numberof data layers which were of interest to the USGS. One of these data layers was the Hydrologic Units. The map is based on the Hydrologic Unit Maps published by the U.S. Geological Survey Office of Water Data Coordination, together with the list descriptions and name of region, subregion, accounting units, and cataloging unit. The hydrologic units are encoded with an eight-digit number that indicates the hydrologic region (first two digits), hydrologic subregion (second two digits), accounting unit (third two digits), and cataloging unit (fourth two digits). The data produced by GIRAS was originally collected at a scale of 1:250K. Some areas, notably major cities in the west, were recompiled at a scale of 1:100K. In order to join the data together and use the data in a geographic information system (GIS) the data were processed in the ARC/INFO GUS software package. Within the GIS, the data were edgematched and the neatline boundaries between maps were removed to create a single data set for the conterminous

  1. Study on Laser Transformation Hardening of HT250 by High Speed Axis Flow CO2 Laser

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    In this article, laser transformation hardening of HT250 material by high speed axis flow CO2 laser was investigated for first time in China. Appropriate laser hardening parameters, such as laser energy power P(W), laser scanning rate V(m/min),were optimized through a number of experiments. The effect of the mentioned parameters on the hardened zone, including its case depth, microhardness distributions etc., were analyzed. Through the factual experiments, it is proved that axial flow CO2 laser, which commonly outputs low mode laser beam, can also treat materials as long as the treating parameters used are rational. During the experiments, the surface qualities of some specimens treated by some parameters were found to be enhanced, which does not coincide with the former results. Furthermore in the article, the abnormal phenomenon observed in the experiments is discussed. According to the experimental results, the relationship between laser power density q and scanning rate V is shown in a curve and the corresponding formulation, which have been proved to be valuable for choosing the parameters of laser transformation hardening by axial flow CO2 lasers, was also given.

  2. A star forming ring around Kappa Ori 250 pc from the Sun

    CERN Document Server

    Pillitteri, I; Megeath, S T

    2016-01-01

    X-rays are a powerful probe of activity in early stages of star formation. They allow us to identify young stars even after they have lost the IR signatures of circumstellar disks and provide constraints on their distance. Here we report on XMM-Newton observations which detect 121 young stellar objects (YSOs) in two fields between L1641S and $\\kappa$ Ori. These observations extend the Survey of Orion A with XMM and Spitzer (SOXS). The YSOs are contained in a ring of gas and dust apparent at millimeter wavelengths, and in far-IR and near-IR surveys. The X-ray luminosity function of the young stellar objects detected in the two fields indicates a distance of 250-280 pc, much closer than the Orion A cloud and similar to distance estimates of $\\kappa$ Ori. We propose that the ring is a 5-8 pc diameter shell that has been swept up by $\\kappa$ Ori. This ring contains several groups of stars detected by Spitzer and WISE including one surrounding the Herbig Ae/Be stars V1818 Ori. In this interpretation, the $\\kappa$ ...

  3. FLUKA simulations and measurements for a dump for a 250 GeV/c hadron beam

    CERN Document Server

    Agosteo, S; Para, A; Silari, Marco; Ulrici, L

    2001-01-01

    FLUKA is a Monte Carlo code, transporting hadron and lepton cascades from several TeV down to a few keV (thermal energies for neutrons). The code is widely employed in various applications, such as particle detector design, shielding, radiation therapy, high energy physics experiments. The FLUKA results were compared with experimental data of dose equivalent and spectral fluence of neutrons produced by a 250 GeV/c proton/pion beam impinging on a beam dump installed in one of the secondary beam lines of the CERN super proton synchrotron (SPS). The dump is a shielding structure made of iron/concrete, designed to absorb completely the high-energy beam. The actual geometry of the clump was modeled in the simulations and the scoring of neutron track length was performed at various locations around it. Importance sampling and Russian Roulette mere used as variance reduction techniques. The simulations results were compared with experimental measurements performed with a Bonner sphere system for neutron spectrometry...

  4. Optical emission from a small scale model electric arc furnace in 250-600 nm region

    Science.gov (United States)

    Mäkinen, A.; Niskanen, J.; Tikkala, H.; Aksela, H.

    2013-04-01

    Optical emission spectroscopy has been for long proposed for monitoring and studying industrial steel making processes. Whereas the radiative decay of thermal excitations is always taking place in high temperatures needed in steel production, one of the most promising environment for such studies are electric arc furnaces, creating plasma in excited electronic states that relax with intense characteristic emission in the optical regime. Unfortunately, large industrial scale electric arc furnaces also present a challenging environment for optical emission studies and application of the method is not straightforward. To study the usability of optical emission spectroscopy in real electric arc furnaces, we have developed a laboratory scale DC electric arc furnace presented in this paper. With the setup, optical emission spectra of Fe, Cr, Cr2O3, Ni, SiO2, Al2O3, CaO, and MgO were recorded in the wavelength range 250-600 nm and the results were analyzed with the help of reference data. The work demonstrates that using characteristic optical emission, obtaining in situ chemical information from oscillating plasma of electric arc furnaces is indeed possible. In spite of complications, the method could possibly be applied to industrial scale steel making process in order to improve its efficiency.

  5. 三星SCH-S250拍照手机

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    这款拍照手机采用了三星同宾得合作推出的500万像素CCD影像传感器,具有1Ocm微距拍摄能力.快门速度达到1/1000s。机身上采用了:320×240像素的160万色QVGA TFD-LCD显示屏。可以进行文本朗读、以QVGA标准进行视频拍摄,内置了92MB的闪存.32MB系统内存。此外,它还支持TTS以及MP3播放能力等。具有MP3播放、支持视频输出并且兼容MMC存储卡。SCH-S250的机身尺寸为115mm×50mm×19mm,重量为116g。

  6. Analysis of Coastal Sediment Plume Dynamics in Puerto Rico using MODIS/Terra 250-m Imagery

    Science.gov (United States)

    Otis, D. B.; Muller-Karger, F. E.; Mendez-Lazaro, P.; McCarthy, M.; Chen, F. R.

    2014-12-01

    Anomalous events of suspended sediments can degrade water quality in nearshore ecosystems by reducing light penetration, inhibiting primary production, and delivering pollutants associated with the sediment particles. Coral reefs, for example, are subject to stress by anomalous sediment loads. The island of Puerto Rico has a diverse topography, with steep mountain slopes, episodic high-intensity rainfall events, and weathered soils that lead to episodes of high sediment volumes being delivered to the coastal zone by rivers. We developed a time series of turbidity observations based on Moderate Resolution Imaging Spectroradiometer (MODIS) imagery for use in the coastal areas of Puerto Rico. The product uses remote-sensing reflectance (Rrs) of Band 1 (645 nm) at a spatial resolution of 250 m. These estimates were compared to in-situ turbidity measurements collected in San Juan Bay. Sediment plumes from the major rivers of Puerto Rico were assessed quantitatively and compared with time-series of meteorological and other parameters, including precipitation, river discharge, and wind velocity. The spatial extent of plumes, the timing and duration of plume events, and their potential impact on coral reefs are examined. Results show that plume events are episodic and short-lived, but that they may affect coral reefs located several kilometers offshore.

  7. The Spectrum of Thorium from 250 nm to 5500 nm: Ritz Wavelengths and Optimized Energy Levels

    CERN Document Server

    Redman, Stephen L; Sansonetti, Craig J

    2013-01-01

    We have made precise observations of a thorium-argon hollow cathode lamp emission spectrum in the region between 350 nm and 1175 nm using a high-resolution Fourier transform spectrometer. Our measurements are combined with results from seven previously published thorium line lists (Giacchetti et al. 1974; Zalubas & Corliss 1974; Zalubas 1976; Palmer & Engleman 1983; Engleman et al. 2003; Lovis & Pepe 2007; Kerber et al. 2008) to re-optimize the energy levels of neutral, singly-, and doubly-ionized thorium (Th I, Th II, and Th III). Using the optimized level values, we calculate accurate Ritz wavelengths for 19679 thorium lines between 250 nm and 5500 nm (40000 1/cm to 1800 1/cm). We have also found 102 new thorium energy levels. A systematic analysis of previous measurements in light of our new results allows us to identify and propose corrections for systematic errors in Palmer & Engleman (1983) and typographical errors and incorrect classifications in Kerber et al. (2008). We also found a la...

  8. Updating the CSNS injector linac to 250 MeV with superconducting double-spoke cavities

    CERN Document Server

    Zhi-Hui, LI

    2014-01-01

    In order to update the beam power from 100 kW to 250 kW in China spallation neutron source (CSNS) Phase II, one of the important measures is to replace the 80 meters long beam transport line between the present 80 MeV linac injector and the RCS to another kind of acceleration structure. In this paper, we proposed a scheme based on 324 MHz double-spoke superconducting cavities. Unlike the superconducting elliptical cavity and normal conducting CCL structure, the double-spoke cavity belongs to TE mode structure and has smaller transvers dimension compared with that of TH mode one. It can work at base frequency as the DTL section, so that the cost and complexity of the RF system will be much decreased, and the behaviors of the beam dynamics are also improved significantly because of the low charge density and larger longitudinal acceptance. Furthermore, because of the relatively longer interactive length between charged particle and the electromagnetic field per cell, it needs relatively less cell numbers and it...

  9. A STAR-FORMING RING AROUND κ Ori 250 pc FROM THE SUN

    Energy Technology Data Exchange (ETDEWEB)

    Pillitteri, I.; Wolk, S. J. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Megeath, S. T., E-mail: ipillitt@cfa.harvard.edu [Ritter Astrophysical Research Center, Department of Physics and Astronomy, University of Toledo, Toledo, OH (United States)

    2016-04-01

    X-rays are a powerful probe of activity in early stages of star formation. They allow us to identify young stars even after they have lost the IR signatures of circumstellar disks and provide constraints on their distance. Here, we report on XMM-Newton observations that detect 121 young stellar objects (YSOs) in two fields between L1641 S and κ Ori. These observations extend the Survey of Orion A with XMM and Spitzer (SOXS). The YSOs are contained in a ring of gas and dust apparent at millimeter wavelengths, and in far-IR and near-IR surveys. The X-ray luminosity function of the YSOs detected in the two fields indicates a distance of 250–280 pc, much closer than the Orion A cloud and similar to distance estimates of κ Ori. We propose that the ring is a 5–8 pc diameter shell that has been swept up by κ Ori. This ring contains several groups of stars detected by Spitzer and WISE including one surrounding the Herbig Ae/Be stars V1818 Ori. In this interpretation, the κ Ori ring is one of several shells swept up by massive stars within the Orion Eridanus Superbubble and is unrelated to the southern portion of Orion A/L1641 S.

  10. Performance of a 512 x 512 Gated CMOS Imager with a 250 ps Exposure Time

    Energy Technology Data Exchange (ETDEWEB)

    Teruya, A T; Moody, J D; Hsing, W W; Brown, C G; Griffin, M; Mead, A S; Tran, V

    2012-10-01

    We describe the performance of a 512x512 gated CMOS read out integrated circuit (ROIC) with a 250 ps exposure time. A low-skew, H-tree trigger distribution system is used to locally generate individual pixel gates in each 8x8 neighborhood of the ROIC. The temporal width of the gate is voltage controlled and user selectable via a precision potentiometer. The gating implementation was first validated in optical tests of a 64x64 pixel prototype ROIC developed as a proof-of-concept during the early phases of the development program. The layout of the H-Tree addresses each quadrant of the ROIC independently and admits operation of the ROIC in two modes. If “common mode” triggering is used, the camera provides a single 512x512 image. If independent triggers are used, the camera can provide up to four 256x256 images with a frame separation set by the trigger intervals. The ROIC design includes small (sub-pixel) optical photodiode structures to allow test and characterization of the ROIC using optical sources prior to bump bonding. Reported test results were obtained using short pulse, second harmonic Ti:Sapphire laser systems operating at λ~ 400 nm at sub-ps pulse widths.

  11. Utilization and operating experience of the 250 kw TRIGA Mark II research reactor in Ljubljana

    International Nuclear Information System (INIS)

    In its 35th year, the TRIGA Mark II 250 kW pulsing research reactor in Ljubljana is continuing its busy operation. With the maximum neutron flux in the central thimble of 10 13 n/cm 2 sec and many sample radiation positions the reactor has been used to perform many experiments in the following fields: solid state physics (elastic and inelastic neutron scattering), neutron dosimetry, neutron radiography, reactor physics including burn up measurements and calculations, boron neutron capture therapy and neutron activation analysis which represents one of the major usage of our reactor. Besides these, applied research around the reactor has been conducted, such as doping of silicon monocrystals, a routine production of various radioactive isotopes for industry ( 60Co, 64Zn, 24Na, 82Br) and medical use ( 18F, 99m Tc, etc.) and other activities. During the past decade the reactor was almost completely reconstructed (new grid plates, the control mechanisms and the control unit, modification of the spent fuel storage pool, etc). The main novelty in the reactor physics and operation features of the reactor was the installation of a pulse rod, therefore the reactor can be operated in a pulse mode. After reconstruction, the core was loaded with fresh 20% enriched fuel elements. In 1999 all spent fuel elements were shipped to the USA. (author)

  12. Isolation of a 250 million-year-old halotolerant bacterium from a primary salt crystal

    Science.gov (United States)

    Vreeland, Russell H.; Rosenzweig, William D.; Powers, Dennis W.

    2000-10-01

    Bacteria have been found associated with a variety of ancient samples, however few studies are generally accepted due to questions about sample quality and contamination. When Cano and Borucki isolated a strain of Bacillus sphaericus from an extinct bee trapped in 25-30 million-year-old amber, careful sample selection and stringent sterilization techniques were the keys to acceptance. Here we report the isolation and growth of a previously unrecognized spore-forming bacterium (Bacillus species, designated 2-9-3) from a brine inclusion within a 250million-year-old salt crystal from the Permian Salado Formation. Complete gene sequences of the 16S ribosomal DNA show that the organism is part of the lineage of Bacillus marismortui and Virgibacillus pantothenticus. Delicate crystal structures and sedimentary features indicate the salt has not recrystallized since formation. Samples were rejected if brine inclusions showed physical signs of possible contamination. Surfaces of salt crystal samples were sterilized with strong alkali and acid before extracting brines from inclusions. Sterilization procedures reduce the probability of contamination to less than 1 in 10 9.

  13. Partial covering of emission regions of Q 0528-250 by intervening H$_2$ clouds

    CERN Document Server

    Klimenko, V V; Ivanchik, A V; Ledoux, C; Noterdaeme, P; Petitjean, P; Srianand, R; Varshalovich, D A

    2015-01-01

    We present an analysis of the molecular hydrogen absorption system at z$_{\\rm abs}$ = 2.811 in the spectrum of the blazar Q0528-250. We demonstrate that the molecular cloud does not cover the background source completely. The partial coverage reveals itself as a residual flux in the bottom of saturated H_2 absorption lines. This amounts to about (2.22$\\pm$0.54)% of the continuum and does not depend on the wavelength. This value is small and it explains why this effect has not been detected in previous studies of this quasar spectrum. However, it is robustly detected and significantly higher than the zero flux level in the bottom of saturated lines of the Ly-alpha forest, (-0.21$\\pm$0.22)%. The presence of the residual flux could be caused by unresolved quasar multicomponents, by light scattered by dust, and/or by jet-cloud interaction. The H$_2$ absorption system is very well described by a two-component model without inclusion of additional components when we take partial coverage into account. The derived t...

  14. Application of CMT Cold Metal Transfer Welding Technology in HT250 Repair Welding%CMT冷金属过渡焊接技术在HT250灰铸铁补焊中的应用

    Institute of Scientific and Technical Information of China (English)

    杨新华; 管志花

    2013-01-01

    阐述了利用CMT冷金属过渡方法补焊HT250灰铸铁的焊接工艺及补焊结果,主要从CMT冷金属过渡方法的特点、HT250灰铸铁焊接工艺和补焊质量3个方面进行了论述和试验研究,总结CMT自动焊技术在补焊铸铁方面的经验,为灰铸铁铸件的补焊提供科学依据和技术参考.%The welding process and the welding result of HT250 gray cast iron using CMT cold metal transfer welding methods were described,that is mainly discussed and researched from three aspects of the characteristics of CMT cold metal transfer method,welding process and welding quality of HT250 gray cast iron.The experience of CMT automatic welding technology in welding of cast iron was summarized,which provide scientific basis and technical references for repair welding of grey iron castings.

  15. 合成大麻素JWH-250的高效液相色谱分析方法研究%Determination of Synthetic Cannabinoid JWH-250 by HPLC

    Institute of Scientific and Technical Information of China (English)

    苗翠英; 邱志远; 翟晚枫; 魏巍; 全雪峰; 王兆玉

    2015-01-01

    Objective As one kind of the most popular designer drugs, synthetic cannabinoid has been presenting a tough challenge for law enforcement and public security officials. JWH-250, one of the phenacyl-indoles abused all around the world, has recently been included under the latest Psychotropic Drug Directory by Chinese government. In order to improve the accuracy and sensitivity of determining JWH-250 in actual cases and enrich the research means for this drug, high performance liquid chromatography (HPLC) was utilized. Methods Chromatographic parameters were tested and optimized based on the performance of least interference to the results quality and repeatedness, together with the ascertainment of linear relationship, precision and stability. Eventually, the ideal conditions for detection of the synthetic cannabinoid JWH-250 by HPLC were established. Results Under optimized conditions (UV wavelength at 214 nm, initial concentration of the organic phase of 63%, gradient steepness of 4.2%/min, flow rate of 0.8 mL/min, and column temperature of 34°C), a good linearity was achieved over the range of 2~100 μg/ml, with the correlation coefficient R=0.9999649 and limit of detection(S/N≥3) as to 0.1 μg/mL. The precision was good with the intra-day and inter-day RSDs less than 0.59% and 1.74%, respectively. JWH-250 can be completely separated from Δ9-tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD). Conclusions The method is rapid, sensitive and accurate, applicable to quantitative determination of the synthetic cannabinoid JWH-250 by validation experiment of a sample from an actual case, a promising choice for providing technical support to prevent and combat the drug-related criminal activities.%目的:建立合成大麻素 JWH-250的高效液相色谱分析方法。方法考查梯度洗脱的有机相初始浓度和梯度洗脱的陡度、流速、柱温、检测波长等参数,初步建立 JWH250的高效液相色谱分析方法,并对专

  16. Shiprock, AZ NM CO UT 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  17. 30 CFR 250.1163 - How must I measure gas flaring or venting volumes and liquid hydrocarbon burning volumes, and...

    Science.gov (United States)

    2010-07-01

    ..., and Burning Hydrocarbons § 250.1163 How must I measure gas flaring or venting volumes and liquid... vented, and liquid hydrocarbons burned, to Minerals Revenue Management on Form MMS-4054 (Oil and Gas... gas flaring, gas venting, and liquid hydrocarbon burning for each facility for 6 years. (1) You...

  18. Evaluation of the Performance of Vortex Generators on the DU 91-W2-250 Profile using Stereoscopic PIV

    DEFF Research Database (Denmark)

    Velte, Clara Marika; Hansen, Martin Otto Laver; Meyer, Knud Erik;

    2008-01-01

    Stereoscopic PIV measurements investigating the effect of Vortex Generators on the lift force near stall and on glide ratio at best aerodynamic performance have been carried out in the LM Glasfiber wind tunnel on a DU 91-W2-250 profile. Measurements at two Reynolds numbers were analyzed; Re=0...

  19. Evaluation of the Performance of Vortex Generators on the DU 91-W2-250 Profile using Stereoscopic PIV

    DEFF Research Database (Denmark)

    Velte, Clara Marika; Hansen, Martin Otto Laver; Meyer, Knud Erik;

    2009-01-01

    Stereoscopic PIV measurements investigating the effect of Vortex Generators on the lift force near stall and on glide ratio at best aerodynamic performance have been carried out in the LM Glasfiber wind tunnel on a DU 91-W2-250 profile. Measurements at two Reynolds numbers were analyzed; Re=0...

  20. 41 CFR 102-73.250 - Are agencies required to adhere to the policies for locating Federal facilities when purchasing...

    Science.gov (United States)

    2010-07-01

    ...-73.250 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 73-REAL ESTATE ACQUISITION Acquisition by Purchase or... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are agencies required...

  1. Hexakis(urea-jO)zinc(II) dinitrate at 110 and 250 K: uniaxial negative thermal expansion

    NARCIS (Netherlands)

    Smeets, S.; Lutz, M.

    2011-01-01

    The crystal structure of the title compound, [Zn{CO(NH2)2}6]- (NO3)2, has been determined at 110 and 250 K. The structure is stabilized by 12 individual hydrogen bonds, both intra- and intermolecular. Analysis of the thermal expansion tensor, based on unit cells determined over a temperature range o

  2. 19 CFR 123.7 - Manifest used as an entry for unconditionally free merchandise value not over $250.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Manifest used as an entry for unconditionally free merchandise value not over $250. 123.7 Section 123.7 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS RELATIONS WITH CANADA AND MEXICO General Provisions § 123.7 Manifest used...

  3. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Science.gov (United States)

    2010-07-01

    ... Petroleum Institute's Recommended Practice for Operation and Maintenance of Offshore Cranes (API RP 2D... for Offshore Pedestal Mounted Cranes (API Spec 2C), incorporated by reference as specified in 30 CFR... meet the requirements of API Spec 2C, incorporated by reference as specified in 30 CFR 250.198. (e)...

  4. Radioimmunotheapy with [I-131]cG250 in patients with metastasized renal cell cancer : Dosimetric analysis and immunologic response

    NARCIS (Netherlands)

    Brouwers, AH; Buijs, WCAM; Mulders, PFA; de Mulder, PHM; van den Broek, WJM; Mala, C; Oosterwijk, E; Boerman, OC; Corstens, FHM; Oyen, WJG

    2005-01-01

    Purpose: A study was designed to define the therapeutic efficacy, safety, and toxicity of two sequential high-dose treatments of radioimmunotherapy with [I-131]cG250 in patients with metastasized renal cell carcinoma. Here, we report the dosimetric analysis and the relationship between the developme

  5. 30 CFR 250.245 - What hydrogen sulfide (H2S) information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... analysis must be consistent with the EPA's risk management plan methodologies outlined in 40 CFR part 68. ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What hydrogen sulfide (H2S) information must... Documents (docd) § 250.245 What hydrogen sulfide (H2S) information must accompany the DPP or DOCD?...

  6. 78 FR 20326 - Draft Compliance Policy Guide Sec. 100.250 Food Facility Registration-Human and Animal Food...

    Science.gov (United States)

    2013-04-04

    ... HUMAN SERVICES Food and Drug Administration Draft Compliance Policy Guide Sec. 100.250 Food Facility Registration--Human and Animal Food; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing the availability of draft Compliance...

  7. Operation, maintenance, and utilization of 250 kW TRIGA Mark II reactor at the Institute Jozef Stefan, Ljubljana (Yugoslavia))

    International Nuclear Information System (INIS)

    At the Institute 'Jozef Stefan' in Ljubljana 250 kW TRIGA Mark II Reactor has been in operation since May 31, 1966. It is the steady state operated reactor without pulsing capabilities. In the paper the operational data, maintenance and utilization of the reactor are summarized for the first four years of reactor operation. (author)

  8. 30 CFR 250.1729 - After I remove a platform or other facility, what information must I submit?

    Science.gov (United States)

    2010-07-01

    ... Decommissioning Activities Removing Platforms and Other Facilities § 250.1729 After I remove a platform or other facility, what information must I submit? Within 30 days after you remove a platform or other facility, you... 30 Mineral Resources 2 2010-07-01 2010-07-01 false After I remove a platform or other...

  9. Dalhart, NM OK TX CO 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  10. Surface circulation patterns in the Gulf of California derived from MODIS Aqua 250 m

    Science.gov (United States)

    Martínez-Flores, G.; Salinas-González, F.; Gutiérrez de Velasco-Sanromán, G.; Godínez-Orta, L.

    2009-04-01

    The Gulf of California (GC) is a marginal elongated and semi-enclosed sea located at northwest of Mexico, between the Peninsula of Baja California and the mainland Mexico. The considered area average 150 km in width and 1500 km in length, from the mouth of the Colorado River to Cabo Corrientes, Jalisco. It has a maximum depth of 3600 m at the southern inlet and the northern region average 200 m in deep. The study of superficial circulation patterns in the GC is of interest because its relevance to the mechanisms of transport for distribution of a variety of materials -plankton, contaminants, microalgae, etc.- and its association with areas of sedimentary deposits, zones where there is a higher probability for fishing or related to the presence of certain species of marine life. Recent studies explain the circulation of the GC as a result of the Pacific Ocean's forcing, wind, heat fluxes on the sea surface and the interaction between the flow produced by these agents and bathymetry. The objective of this work was to obtain evidence of the patterns of surface circulation using a spatial resolution of 250 m over a period of two to seven days (depending on cloud cover), which offered images from the MODIS Level 1B. This essay is an attempt to contribute with more information to the understanding of the regional dynamics of the GC and its local influence on the zones bordering the coast. Thus, MODIS Aqua 250 m data was used, to which algorithms were applied in order to enhance the contrast of reflectance levels of these bands (0.620-0.670 and 0.841-0.876 µm) within the marine environment. The results are associated with suspended particulate matter (SPM), which we used as tracers of the surface circulation, using a sequence of images from January 2004 to December 2008. Algorithms for dust and cloud detection were used and incorporated with thermal band images, in which zones of terrigenous contribution by eolian transport were identified. Furthermore, pluvial

  11. Study for optimization of a 60 Co industrial irradiator of 250 k Ci

    International Nuclear Information System (INIS)

    This work presents results of a benchmark between calculated and experimental absorbed dose values for a typical product, in a 60 Co industrial irradiator, located at ININ, Mexico. The goal of this work is to reach a ± 10 % approximation between both values. ININ 60 Co industrial irradiator is a two level, two layer system with overlapping product configuration, 56 irradiation positions with an activity of around 250 k Ci. Calculated values were obtained by QAD-CGGP code. This code uses a point kernel technique, build-up factors fitting was done by geometrical progression and combinatorial geometry was used for 3 D system description. Main code modifications were related with source simulation by punctual sources and energy spectrum (16 energy groups) and anisotropic emission were also considered. Experimental data were obtained from routine dosimetry which was done with red acrylic pellets; they were irradiated together the product in predetermined positions, for 36 maximum and minimum absorbed dose values. Typical product was polypropylene Petri dish packages, apparent density 0.13 g/cm3. It was chosen because regular geometry (2 packages per full irradiator container) and enough amount for considering homogeneous loading inside irradiation chamber. Required minimum dose was 15 kGy. Results showed a 8% variation between calculated and experimental values for maximum absorbed dose (18.2 kGy vs 16.8 kGy) and 3 % variation for minimum absorbed dose (13.8 kGy vs 14.3 kGy); these results fixed with the original proposal. (Author)

  12. Study on discharge heat utilization of 250 MWe PCMSR turbine system for desalination using modified MED

    International Nuclear Information System (INIS)

    PCMSR (Passive Compact Molten Salt Reactor) is one type of Advanced Nuclear Reactors. The PCMSR has benefit characteristics of very efficient fuel use, high safety characteristic as well as high thermodynamics efficiency. This is due to its breeding capability, inherently safe characteristic and totally passive safety system. The PCMSR design consists of three module, i.e. reactor module, turbine module and fuel management module. Analysis in performed by parametric calculation of the turbine system to calculate the turbine system efficiency and the hat available for desalination. After that the mass and energy balance of desalination process are calculated to calculate the amount of distillate produced and the amount of feed sea water needed. The turbine module is designed to be operated at maximum temperature cycle of 1373 K (1200 °C) and minimum temperature cycle of 333 K (60 °K). The parametric calculation shows that the optimum turbine pressure ratio is 4.3 that gives the conversion efficiency of 56 % for 4 stages turbine and 4 stages compressor and equipped with recuperator. In this optimum condition, the 250 MWe PCMSR turbine system produces 196 MWth of waste heat with the temperature of cooling fluid in the range from 327 K (54°C) to 368 K (95 °C). This waste heat can be utilized for desalination. By using MMED desalination system, this waste heat can be used to produce fresh water (distillate) from sea water feed. The amount of the distillate produced is 48663 ton per day by using 15 distillation effects. The performance ratio value is 2.8727 with by using 15 distillation effects. (author)

  13. High Resolution PET with 250 micrometer LSO Detectors and Adaptive Zoom

    Energy Technology Data Exchange (ETDEWEB)

    Cherry, Simon R.; Qi, Jinyi

    2012-01-08

    There have been impressive improvements in the performance of small-animal positron emission tomography (PET) systems since their first development in the mid 1990s, both in terms of spatial resolution and sensitivity, which have directly contributed to the increasing adoption of this technology for a wide range of biomedical applications. Nonetheless, current systems still are largely dominated by the size of the scintillator elements used in the detector. Our research predicts that developing scintillator arrays with an element size of 250 {micro}m or smaller will lead to an image resolution of 500 {micro}m when using 18F- or 64Cu-labeled radiotracers, giving a factor of 4-8 improvement in volumetric resolution over the highest resolution research systems currently in existence. This proposal had two main objectives: (i) To develop and evaluate much higher resolution and efficiency scintillator arrays that can be used in the future as the basis for detectors in a small-animal PET scanner where the spatial resolution is dominated by decay and interaction physics rather than detector size. (ii) To optimize one such high resolution, high sensitivity detector and adaptively integrate it into the existing microPET II small animal PET scanner as a 'zoom-in' detector that provides higher spatial resolution and sensitivity in a limited region close to the detector face. The knowledge gained from this project will provide valuable information for building future PET systems with a complete ring of very high-resolution detector arrays and also lay the foundations for utilizing high-resolution detectors in combination with existing PET systems for localized high-resolution imaging.

  14. High Resolution PET with 250 micrometer LSO Detectors and Adaptive Zoom

    International Nuclear Information System (INIS)

    There have been impressive improvements in the performance of small-animal positron emission tomography (PET) systems since their first development in the mid 1990s, both in terms of spatial resolution and sensitivity, which have directly contributed to the increasing adoption of this technology for a wide range of biomedical applications. Nonetheless, current systems still are largely dominated by the size of the scintillator elements used in the detector. Our research predicts that developing scintillator arrays with an element size of 250 (micro)m or smaller will lead to an image resolution of 500 (micro)m when using 18F- or 64Cu-labeled radiotracers, giving a factor of 4-8 improvement in volumetric resolution over the highest resolution research systems currently in existence. This proposal had two main objectives: (i) To develop and evaluate much higher resolution and efficiency scintillator arrays that can be used in the future as the basis for detectors in a small-animal PET scanner where the spatial resolution is dominated by decay and interaction physics rather than detector size. (ii) To optimize one such high resolution, high sensitivity detector and adaptively integrate it into the existing microPET II small animal PET scanner as a 'zoom-in' detector that provides higher spatial resolution and sensitivity in a limited region close to the detector face. The knowledge gained from this project will provide valuable information for building future PET systems with a complete ring of very high-resolution detector arrays and also lay the foundations for utilizing high-resolution detectors in combination with existing PET systems for localized high-resolution imaging.

  15. Statistics and scaling of turbulence in a spatially developing mixing layer at Reλ = 250

    KAUST Repository

    Attili, Antonio

    2012-03-21

    The turbulent flow originating from the interaction between two parallel streams with different velocities is studied by means of direct numerical simulation. Rather than the more common temporal evolving layer, a spatially evolving configuration, with perturbed laminar inlet conditions is considered. The streamwise evolution and the self-similar state of turbulence statistics are reported and compared to results available in the literature. The characteristics of the transitional region agree with those observed in other simulations and experiments of mixing layers originating from laminar inlets. The present results indicate that the transitional region depends strongly on the inlet flow. Conversely, the self-similar state of turbulent kinetic energy and dissipation agrees quantitatively with those in a temporal mixing layer developing from turbulent initial conditions [M. M. Rogers and R. D. Moser, “Direct simulation of a self-similar turbulent mixing layer,” Phys. Fluids6, 903 (1994)]. The statistical features of turbulence in the self-similar region have been analysed in terms of longitudinal velocity structure functions, and scaling exponents are estimated by applying the extended self-similarity concept. In the small scale range (60 < r/η < 250), the scaling exponents display the universal anomalous scaling observed in homogeneous isotropic turbulence. The hypothesis of isotropy recovery holds in the turbulent mixing layer despite the presence of strong shear and large-scale structures, independently of the means of turbulence generation. At larger scales (r/η > 400), the mean shear and large coherent structures result in a significant deviation from predictions based on homogeneous isotropic turbulence theory. In this second scaling range, the numerical values of the exponents agree quantitatively with those reported for a variety of other flows characterized by strong shear, such as boundary layers, as well as channel and wake flows.

  16. Hybrid superconducting a.c. current limiter extrapolation 63 kV-1 250 A

    Science.gov (United States)

    Tixador, P.; Levêque, J.; Brunet, Y.; Pham, V. D.

    1994-04-01

    (150 V/50 A) a permis de valider expérimentalement cette conception. Nous aborderons l'extrapolation d'un limiteur de taille industrielle (63 kV/1 250 A). Les résultats seront comparés à des limiteurs supraconducteurs résistifs et de type DASC.

  17. Biometric Calculation and Refractive Results. A Study of 250 Cases of Patients Operated for Cataract

    Directory of Open Access Journals (Sweden)

    Inés Benita Zamora Galindo

    2012-02-01

    Full Text Available Fundamento: el implante de lentes intraoculares en la cirugía de catarata significa un avance en la corrección refractiva de la afaquia. Pero sin el estudio previo a la cirugía y el correcto cálculo de la lente intraocular, los resultados no serían satisfactorios. Objetivo: evaluar el cálculo biométrico y la refracción posquirúrgica de pacientes operados de cataratas. Metodos: estudio descriptivo realizado en el Centro de Oftalmología del Estado de Anzoátegui, Venezuela, que incluyó 250 pacientes sometidos a cirugía de catarata, a quienes previamente se les realizó refracción, queratometría, biometría y cálculo de lente intraocular. Después de la cirugía se determinó: refracción esperada por el cálculo biométrico, error refractivo posoperatorio, agudeza visual posquirúrgica sin corrección y con corrección. Resultados: predominó el sexo femenino y el grupo de edad entre 60 y 69 años. El valor más registrado de la queratometría  osciló de 43 a 44 dioptrías. El valor de la longitud axial más destacado fue de 22 a 24 mm. Las lentes intraoculares más usadas fueron de 16 a 20 dioptrías y las de 21 a 25 dioptrías. El mayor por ciento de la refracción esperada estuvo en el grupo de 0,00 a 0, 50. El error refractivo que predominó fue el de 0,50 a 1,00. En la refracción realizada al mes de la cirugía, sin cristales, más de la mitad de los pacientes obtuvo visiones entre 20/30 y 20/25. Conclusiones: se demostró la efectividad del cálculo de la lente intraocular previo a la cirugía de catarata.

  18. Interpreting 250m Moderate Resolution Imaging Spectroradiometer Vegetation Indices in the Colorado Plateau, USA

    Science.gov (United States)

    Hamar, M.; White, M.; Lauver, C.; Garman, S.

    2006-12-01

    Semi-arid ecosystems, which are inherently vulnerable to small changes in the amount and distribution of precipitation, are frequently co-located with extensive human habitations and vulnerable species distributions. Important societal considerations identified by GEOSS, such as human health and well-being, ecological services, environmental protection, genetic resources, and disaster risk reduction and mitigation, may be under particular strain from invasive species, demographic changes, and/or climate change in semi-arid ecosystems. Satellite-based remote sensing may therefore be an important tool for monitoring the status of semi-arid ecosystems and habitats. Yet to date, the ability of current generation sensors, such as the Moderate Resolution Imaging Spectroradiometer (MODIS), to accurately represent within-season phenological variability in semi-arid ecosystems a crucial precursor for long-term monitoring is largely unknown. Several programs worldwide seek information on this relationship. As part of one such effort, the Vital Signs Monitoring program for the National Park Service (NPS), we evaluated the ability of the MODIS 250m Normalized Difference Vegetation Index (NDVI), Enhanced Vegetation Index (EVI), and red, near infra-red, and blue channels to represent relative changes in ground-measured vegetation structure. Using an AccuPAR LP-80 PAR/LAI Ceptometer, LAI-2000 Plant Canopy Analyzer, and First Growth digital camera, we sampled plant area index (PAI) and green fractional cover (GFC) at 4 sites along a bioclimatic gradient in the Colorado Plateau, USA, representing semi-arid woodland, mixed grassland/shrubland, and grassland plant functional types. In 14 visits from June 2005 to October 2005, we intensively sampled each site at a spatial resolution directly comparable to 4 MODIS pixels. At each site, PAI was always less than 1.0 and often less than 0.4 and GFC was rarely greater than 5%. Likely due to low plant cover and instrument noise, correlation

  19. THE STUDY OF IMPROVING OF STABILITY AND RELIABILITY FOR 250kV HIGH VOLTAGE POWER%改进250kV高压电源稳定性与可靠性的研究

    Institute of Scientific and Technical Information of China (English)

    廖小东; 郑思孝; 刘仲阳; 孙官清; 王培录

    2001-01-01

    The hitches for a ppearing in the high voltage power at 250kV and improvement of the controlling circuit techniques are described. The static high voltage output was exercised by raising the high voltage gradually. The affects between the current load-variety and the vaviety of the input voltoge at + 1096 against the high voltage stability have been obtained. The experiments prove that the high voltage stability have been raised greatly via improving the controlling circuit.

  20. Does the Loss of ARID1A (BAF-250a Expression in Endometrial Clear Cell Carcinomas Have Any Clinicopathologic Significance? A Pilot Assessment

    Directory of Open Access Journals (Sweden)

    Oluwole Fadare, Idris L. Renshaw, Sharon X. Liang

    2012-01-01

    Full Text Available SWI/SNF chromatin-modification complexes use the energy of ATP hydrolysis to remodel nucleosomes and to affect transcription and several cellular processes. Accordingly, their loss of function has been associated with malignant transformation. ARID1A (the expression of whose product, BAF250a, a key complex component, is lost when mutated has recently been identified as a tumor suppressor gene that is mutated in 46-57% of ovarian clear cell carcinoma (CCC. The purposes of this study are to assess the frequency of loss of BAF250a expression in endometrial CCC and whether this loss has any discernable clinicopathologic implications. 34 endometrial carcinomas with a CCC component (including 22 pure CCC, 8 mixed carcinomas with a 10% CCC component, and 4 carcinosarcomas with a CCC epithelial component, were evaluated by immunohistochemistry using a monoclonal antibody directed against the human BAF250a protein. 5 (22.7% of the 22 pure CCC were entirely BAF250a negative, whereas the remainder showed diffuse immunoreactivity. None of 4 carcinosarcomas and only 1 (12.5% of the 8 mixed carcinomas were BAF250a negative. There was no discernable relationship between BAF250a immunoreactivity status and tumor architectural patterns (solid, papillary or tubulocystic areas or cell type (flat, hobnail or polygonal. Of the 22 patients with pure CCC, 14, 2, 3, and 3 were International Federation of Gynecology and Obstetrics stages 1, II, III and IV respectively. Interestingly, all 5 BAF250a negative cases were late stage [stages III or IV] as compared with 1 of 17 BAF250a positive cases (p=0.0002. Thus, 83% (5/6 of all late stage cases were BAF250a [-], as compared with 0 (0% of the 16 early stage (I or II cases (p=.0002. BAF250a negative and positive cases did not show any statistically significant difference regarding patient age and frequency of lymphovascular invasion or myometrial invasion. As may be anticipated from the concentration of late stage cases in

  1. Determination of Recrystallization Temperature of Reverted Austenite of C-250 Maraging Steel%C-250马氏体时效钢逆变奥氏体再结晶温度的测定

    Institute of Scientific and Technical Information of China (English)

    赵飞; 秦路平; 魏志坚; 张华

    2011-01-01

    Based on the theory of phase transformation and recrystallization accompanied with thermal effect and volume effect, the austenization temperature and reverted austenite recrystallization temperature of C-250 maraging steel was determined by DSC and dilatometer.The austenization temperature is As ≈ 647 ℃ and Af≈ 780 ℃, while the recrystallization temperature of reverted austenite is 923.1 ℃.%利用相变过程和逆变再结晶过程伴随着热效应体积效应的原理,采用热分析和热膨胀相结合的方法来测定C-250马氏体时效钢的奥氏体化温度和逆变奥氏体再结晶温度.结果显示,C-250马氏体时效钢的奥氏体化温度为A≈647℃,A≈780℃,逆变奥氏体再结晶温度为923.1℃.

  2. Performance of 4 mm impact sprinklers at different spacing within acceptable pressure range (250-350 kPa

    Directory of Open Access Journals (Sweden)

    SOROPA GABRIEL,

    2011-03-01

    Full Text Available Single leg tests were conducted to determine performance and cost effectiveness of different spacing combinations that can be used in 4 mm impact sprinkler irrigation systems design operating at 250-350kPa. Four sprinklers were tested for coefficient of uniformity (CU, distribution uniformity (DU and wetted diameter at three different pressure points. Results obtained for CU and DU showed that imported sprinklers had significantly higher water application uniformities than locally made sprinklers at 250-350 kPa pressure range. Sprinkler spacings of 12 m x 18 m and 15 m x 15 m passed the layout tests and can be used in Zimbabwe under moderate wind conditions at 300 kPa, using preferably imported sprinklers for best water application uniformity. Therefore 15 m x 15 m sprinkler spacing which covers alarger area can replace 12 m x 18 m layout in spraylines design without compromising water application uniformity.

  3. 250 kV 6 mA compact Cockcroft-Walton high-voltage power supply

    Science.gov (United States)

    Ma, Zhan-Wen; Su, Xiao-Dong; Lu, Xiao-Long; Wei, Zhen; Wang, Jun-Run; Huang, Zhi-Wu; Miao, Tian-You; Su, Tong-Ling; Yao, Ze-En

    2016-08-01

    A compact power supply system for a compact neutron generator has been developed. A 4-stage symmetrical Cockcroft-Walton circuit is adopted to produce 250 kV direct current high-voltage. A 2-stage 280 kV isolation transformer system is used to drive the ion source power supply. For a compact structure, safety, and reliability during the operation, the Cockcroft-Walton circuit and the isolation transformer system are enclosed in an epoxy vessel containing the transformer oil whose size is about ∅350 mm × 766 mm. Test results indicate that the maximum output voltage of the power supply is 282 kV, and the stability of the output voltage is better than 0.63% when the high voltage power supply is operated at 250 kV, 6.9 mA with the input voltage varying ±10%.

  4. 250 kV 6 mA compact Cockcroft-Walton high-voltage power supply.

    Science.gov (United States)

    Ma, Zhan-Wen; Su, Xiao-Dong; Lu, Xiao-Long; Wei, Zhen; Wang, Jun-Run; Huang, Zhi-Wu; Miao, Tian-You; Su, Tong-Ling; Yao, Ze-En

    2016-08-01

    A compact power supply system for a compact neutron generator has been developed. A 4-stage symmetrical Cockcroft-Walton circuit is adopted to produce 250 kV direct current high-voltage. A 2-stage 280 kV isolation transformer system is used to drive the ion source power supply. For a compact structure, safety, and reliability during the operation, the Cockcroft-Walton circuit and the isolation transformer system are enclosed in an epoxy vessel containing the transformer oil whose size is about ∅350 mm × 766 mm. Test results indicate that the maximum output voltage of the power supply is 282 kV, and the stability of the output voltage is better than 0.63% when the high voltage power supply is operated at 250 kV, 6.9 mA with the input voltage varying ±10%.

  5. 250 kV 6 mA compact Cockcroft-Walton high-voltage power supply.

    Science.gov (United States)

    Ma, Zhan-Wen; Su, Xiao-Dong; Lu, Xiao-Long; Wei, Zhen; Wang, Jun-Run; Huang, Zhi-Wu; Miao, Tian-You; Su, Tong-Ling; Yao, Ze-En

    2016-08-01

    A compact power supply system for a compact neutron generator has been developed. A 4-stage symmetrical Cockcroft-Walton circuit is adopted to produce 250 kV direct current high-voltage. A 2-stage 280 kV isolation transformer system is used to drive the ion source power supply. For a compact structure, safety, and reliability during the operation, the Cockcroft-Walton circuit and the isolation transformer system are enclosed in an epoxy vessel containing the transformer oil whose size is about ∅350 mm × 766 mm. Test results indicate that the maximum output voltage of the power supply is 282 kV, and the stability of the output voltage is better than 0.63% when the high voltage power supply is operated at 250 kV, 6.9 mA with the input voltage varying ±10%. PMID:27587170

  6. Experimental '' of As at 170, 200, 250 and 300 K from the Bijvoet pairs of GaAs

    Indian Academy of Sciences (India)

    G Raja Sudha; K Vimala Devi; D Arthi; S Prasanna Subramanian; N Srinivasan; R Saravanan

    2002-08-01

    Anomalous dispersion effects lead to the modification of the measured X-ray structure factors. In this work, we have determined the imaginary part of the anomalous dispersion correction terms ('' ) of arsenide atom (As), through the X-ray data collected using spherical single crystal of GaAs, at various temperatures, i.e. 170, 200, 250 and 300 K. It is stressed that more measurements of '' of the elements are needed to confirm the theoretical calculations.

  7. Complete Set of Deuteron Analyzing Powers for dp Elastic Scattering at 250 MeV/nucleon and Three Nucleon Forces

    Directory of Open Access Journals (Sweden)

    Shimizu Y.

    2010-04-01

    Full Text Available Measurements of a complete set of deuteron analyzing powers (iT11, T20, T21, T22 for elastic deuteron–proton scattering at 250 MeV/nucleon have been performed with polarized deuteron beams at RIKEN RI Beam Factory. The obtained data are compared with the Faddeev calculations based on the modern nucleon–nucleon forces together with the Tucson-Melbourne’99, and UrbanaIX three nucleon forces.

  8. Digital standard cells and operational amplifiers for operation up to 250 degrees C using low-cost CMOS technology

    Science.gov (United States)

    Stemmer, Jens; Ackermann, Joerg; Uffmann, Dirk; Aderhold, Jochen

    1996-09-01

    There is an increasing demand from automotive, aircraft and space industry for reliable high temperature resistant electronics. Circuits with reliable functionality up to temperatures of 250 degree(s)C would be sufficient for most of these applications. Digital standard cells and operational amplifiers are the basic building blocks of these circuits. Commercially available digital standard cell libraries and operational amplifiers are normally specified for operation up to a maximum temperature of 125 degree(s)C. Hence, the purpose of this work was the design and characterization of digital standard cells and operational amplifiers for operation up to 250 degree(s)C using a low-cost 1.0 micrometers epi-CMOS process. Several design measures were applied to the cells in order to further improve latch-up resistivity and to limit leakage currents, respectively. The transfer curves of all digital cells for all input signal combinations have been recorded in the temperature range from 30 to 250 degree(s)C. Significant results are very low temperature shifts of the noise margins and of the switching point, respectively. Furthermore, the low (0 V) and high (5 V) levels are reached exactly over the entire temperature range. Outstanding characteristics of the operational amplifier comprise low open-loop gain temperature drift as well as low offset and offset temperature drift, respectively. The open-loop gain was greater than 83 dB at room temperature with a drift of less than 0.02 dB/ degree(s)C. The offset voltage amounted to -1 mV at room temperature and 1 mV at 250 degree(s)C, respectively. The long-term behavior of these cells is currently under investigation.

  9. Phenotypic expression of the fibroblast growth factor receptor 3 (FGFR3) mutation P250R in a large craniosynostosis family.

    OpenAIRE

    Golla, A; Lichmer, P; von Gernet, S; Winterpacht, A; Fairley, J.; Murken, J.; Schuffenhauer, S.

    1997-01-01

    The craniosynostosis syndromes are a heterogeneous group of sporadic, autosomal dominant disorders with significant clinical overlap. Recently, we described a large family with autosomal dominant craniosynostosis suggestive of Saethre-Chotzen syndrome, in which linkage to the Saethre-Chotzen syndrome loci on 7p had been excluded. We now report the presence of a mutation in the fibroblast growth factor receptor 3 (FGFR3) in this family. The mutation, P250R, had been previously reported in 10 p...

  10. Downscaling 250-m MODIS Growing Season NDVI Based on Multiple-Date Landsat Images and Data Mining Approaches

    OpenAIRE

    Yingxin Gu; Bruce K. Wylie

    2015-01-01

    The satellite-derived growing season time-integrated Normalized Difference Vegetation Index (GSN) has been used as a proxy for vegetation biomass productivity. The 250-m GSN data estimated from the Moderate Resolution Imaging Spectroradiometer (MODIS) sensors have been used for terrestrial ecosystem modeling and monitoring. High temporal resolution with a wide range of wavelengths make the MODIS land surface products robust and reliable. The long-term 30-m Landsat data provide spatial detaile...

  11. 30 CFR 250.465 - When must I submit an Application for Permit to Modify (APM) or an End of Operations Report to MMS?

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations Applying for A Permit to Modify and Well Records § 250.465... of § 250.412. (3) Move a drilling unit from a wellbore before completing a well Submit forms...

  12. MODIS/TERRA MOD44W Land Water Mask Derived from MODIS and SRTM L3 Global 250m SIN Grid

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Land Water Mask Derived from MODIS and SRTM L3 Global 250m SIN Grid MOD44W The new MODIS 250 m land-water mask (Short Name: MOD44W) is an improvement over the...

  13. 30 CFR 250.1156 - What steps must I take to receive approval to produce within 500 feet of a unit or lease line?

    Science.gov (United States)

    2010-07-01

    ... produce within 500 feet of a unit or lease line? 250.1156 Section 250.1156 Mineral Resources MINERALS... I take to receive approval to produce within 500 feet of a unit or lease line? (a) You must obtain... any portion of the completed interval less than 500 feet from a unit or lease line. Submit to MMS...

  14. 12 CFR 250.220 - Whether member bank acting as trustee is prohibited by section 20 of the Banking Act of 1933 from...

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Whether member bank acting as trustee is prohibited by section 20 of the Banking Act of 1933 from acquiring majority of shares of mutual fund. 250.220 Section 250.220 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE...

  15. 12 CFR 250.408 - Short-term negotiable notes of banks not securities under section 32, Banking Act of 1933.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Short-term negotiable notes of banks not securities under section 32, Banking Act of 1933. 250.408 Section 250.408 Banks and Banking FEDERAL RESERVE... securities under section 32, Banking Act of 1933. (a) The Board of Governors has been asked whether...

  16. Late radiation fibrosis in rat lung following protons and 250 kV X-rays irradiation

    International Nuclear Information System (INIS)

    To investigate the biological effectiveness of proton beams in the development of pulmonary fibrosis the lungs of male 7-week-old Wistar rats were locally irradiated with a single dose of 10-50 Gy of 250 kV X-rays and modulated, 250 MeV protons at Particle Radiation Medical Science Center (PARMS). Animals were sacrificed serially after 3, 6, 9, and 12 months at which times the development of the fibrotic lesion in alveolar walls and peribonchial connective tissues was assessed quantitatively by analysis of microscopic image of Azan-Mallory stained sections. Fibrosis index (FI) values in alveolar walls and peribronchial tissues were defined as the fraction (in percent) of a specific image area, the gray level of which represents collagen deposits. Using this FI values, the increase of fibrotic lesion following 0-40 Gy of X-rays irradiation as a function of time were observed better in alveolar walls than in peribronchial tissues. Compared with 250 kV X-rays, 30 Gy of proton beams irradiation produced less increase in the time course of FI values of alveolar walls and dose-response curve at 12 months later suggested that the fibrotic lesion in alveolar walls after protons exposure to the doses above 30 Gy might develop more slowly. (author) 51 refs

  17. The G-250A polymorphism in the hepatic lipase gene promoter is associated with changes in hepatic lipase activity and LDL cholesterol: The KANWU Study

    DEFF Research Database (Denmark)

    Lindi, Virpi; Schwab, Ursula; Louheranta, Anne;

    2007-01-01

    acids (SFA diet) or monounsaturated fatty acids (MUFA diet). Within groups there was a second random assignment to supplements with fish oil (3.6g n-3 FA/day) or placebo. At baseline, the A-250A genotype was associated with high serum LDL cholesterol concentration (P=0.030 among three genotypes......). On the MUFA diet carriers of the A-250A genotype presented a greater decrease in LDL cholesterol concentration than subjects with other genotypes (P=0.007 among three genotypes). The rare -250A allele was related to low HL activity (P... activity among the genotypes. CONCLUSION: The A-250A genotype of the LIPC gene was associated with high LDL cholesterol concentration, but the MUFA-enriched diet reduced serum LDL cholesterol concentration especially in subjects with the A-250A genotype. Udgivelsesdato: 2008-Feb...

  18. Should the dose of tenofovir be reduced to 200–250 mg/day, when combined with protease inhibitors?

    Directory of Open Access Journals (Sweden)

    Andrew Hill

    2014-11-01

    Full Text Available Introduction: The approved dose of tenofovir disproxil fumarate, 300 mg once daily, was established in clinical trials in combination with efavirenz, which does not significantly affect tenofovir concentrations. Combining tenofovir with lopinavir/r, darunavir/r or atazanavir/r increases tenofovir concentrations, which could raise the risk of renal adverse events. Newly approved tenofovir tablets are available at lower strength (200 or 250 mg for use in paediatrics. Methods: A literature search was used to assess the effects of lopinavir/r, darunavir/r and atazanavir/r on tenofovir plasma Cmax, AUC and Cmin (Geometric Mean Ratio and 90% confidence intervals. Assuming linear dose-proportional pharmacokinetics (as observed in dose-ranging studies, the 250 mg tablet was predicted to achieve plasma concentrations 17% lower than the 300 mg dose, and the 200 mg tablet to achieve plasma levels 33% lower. Effects on tenofovir plasma Cmax, AUC and Cmin concentrations were assessed for combined dosing of each protease inhibitor with 250 or 200 mg daily doses of tenofovir, versus standard dose tenofovir (300 mg daily without protease inhibitors. Results: In drug-drug interaction studies, lopinavir/ritonavir significantly increased tenofovir Cmax, AUC and Cmin. Effects of each PI on tenofovir Cmin were greater than effects on Cmax or AUC. Using a 250 mg paediatric dose of tenofovir with lopinavir/ritonavir, tenofovir Cmin was predicted to remain higher than tenofovir 300 mg used with efavirenz (GMR=1.26, 95% CI 1.14–1.38. Similar results were observed for use of tenofovir 250 mg with atazanavir/ritonavir (GMR=1.07, 95% CI 1.01–1.13 and with darunavir/ritonavir (GMR=1.14, 95% CI 0.99–1.31. Predicted tenofovir AUC levels for the 250 mg dose with protease inhibitors were all within the bioequivalence range, relative to use with efavirenz. Using a 200 mg paediatric dose of tenofovir with lopinavir/ritonavir, the tenofovir Cmin was predicted to be

  19. 250例早期先兆流产病人妊娠结局及其影响因素分析%Analysis on pregnancy outcome and its influencing factors of 250 women with early threatened miscarriage

    Institute of Scientific and Technical Information of China (English)

    黄春梅; 区少心; 潘秀丽

    2013-01-01

    [目的]探讨250例早期先兆流产病人妊娠结局及其影响因素.[方法]应用自制的调查问卷对250例早期先兆流产病人进行调查,分析不良妊娠结局发生率与影响因素.[结果]本组250例,出现不良结局70例(28.00%);高龄、多次流产史、从事物理化学毒物接触职业、低收入、阴道大出血、宫内大血肿孕妇的不良妊娠结局发生率显著高于良好结局者(P<0.05);Logistic回归分析显示,阴道大量出血、职业性质、既往流产史与不良妊娠结局发生率显著相关(P<0.05),而年龄、家庭收入、宫内血肿没有绝对相关性(P>0.05).[结论]早期先兆流产病人不良妊娠结局发生率相对较高,阴道出血量、职业性质、既往流产史是不良妊娠结局的独立危险因素,高龄、家庭低收入、宫内大血肿是可能的危险因素.

  20. Effect of Diacetyl Monoxime Thiosemicarbazone on the Corrosion of Aged 18 Ni 250 Grade Maraging Steel in Sulphuric Acid Solution

    Directory of Open Access Journals (Sweden)

    T. Poornima

    2012-01-01

    Full Text Available The corrosion inhibition of the aged 18 Ni 250 grade maraging steel in 0.5 M sulphuric acid by diacetyl monoxime thiosemicarbazone (DAMTSC at 303–323 K has been investigated by potentiodynamic polarization, EIS, and SEM techniques. Good inhibition efficiency of DAMTSC was revealed even at low concentrations, which increased with the increase in DAMTSC concentration and decreased with the increase in temperature. The activation energies, , as well as other thermodynamic parameters (; ; , were evaluated and discussed. The adsorption of DAMTSC on the aged maraging steel surface was found to obey the Langmuir adsorption isotherm model and shows mixed type inhibition behavior.

  1. Serendipitous detection of an overdensity of Herschel-SPIRE 250 μm sources south of MRC 1138-26

    Science.gov (United States)

    Valtchanov, Ivan; Altieri, B.; Berta, S.; Chapin, E.; Coia, D.; Conversi, L.; Dannerbauer, H.; Domínguez-Sánchez, H.; Rawle, T. D.; Sánchez-Portal, M.; Santos, J. S.; Temporin, S.

    2013-12-01

    We report the serendipitous detection of a significant overdensity of Herschel-Spectral and Photometric Imaging Receiver 250 μm sources in the vicinity of MRC 1138-26. We use an adaptive kernel density estimate to quantify the significance, including a comparison with other fields. The overdensity has a size of ˜3.5-4 arcmin and stands out at ˜5σ with respect to the background estimate. No features with similar significance were found in four Herschel-observed extragalactic control fields: GOODS-North, Lockman, COSMOS and UDS. The chance of having a similar overdensity in a field with the same number but randomly distributed sources is less than 2 per cent. The clump is also visible as a low-surface-brightness feature in the Planck 857 GHz map. We detect 76 sources at 250 μm (with a signal-to-noise ratio greater than 3), in a region of 4 arcmin radius (or 1.51 ± 0.17 arcmin-2); 43 of those (or 0.86 ± 0.13 arcmin-2) are above a flux density limit of 20 mJy. This is a factor of 3.6 in excess over the average 0.24 ± 0.02 arcmin-2 in the four control fields, considering only the sources above 20 mJy. We also find an excess in the number counts of sources with 250 μm flux densities between 30 and 40 mJy, compared to deep extragalactic blank-field number counts. Assuming a fixed dust temperature (30 K) and emissivity (β = 1.5), a crude, blackbody-derived redshift distribution, zBB, of the detected sources is significantly different from the distributions in the control fields and exhibits a significant peak at zBB ≈ 1.5, although the actual peak redshift is highly degenerate with the temperature. We tentatively suggest, based on zBB and the similar S250/S350 colours of the sources within the peak, that a significant fraction of the sources in the clump may be at a similar redshift. Since the overdensity lies ˜ 7 arcmin south of the z = 2.16 Spiderweb protocluster MRC 1138-26, an intriguing possibility (that is presently unverifiable given the data in hand

  2. Evaluation of the Performance of Vortex Generators on the DU 91-W2-250 Profile using Stereoscopic PIV

    Directory of Open Access Journals (Sweden)

    Knud Erik Meyer

    2009-06-01

    Full Text Available Stereoscopic PIV measurements investigating the effect of Vortex Generators on the lift force near stall and on glide ratio at best aerodynamic performance have been carried out in the LM Glasfiber wind tunnel on a DU 91-W2-250 profile. Measurements at two Reynolds numbers were analyzed; Re=0.9·10 6 and 2.4·10 6 . The results show that one can resolve the longitudinal vortex structures generated by the devices and that mixing is created close to the wall, transferring high momentum fluid into the near wall region. It is also seen that the vortex generators successfully can obstruct separation near stall.

  3. Transverse-momentum fluctuations in $\\pi^{+}p$ and $K^{+}p$ collisions at 250 GeV/c

    CERN Document Server

    Ataian, M R; De Wolf, E A; Endler, A M F; Fu Jing Hua; Gulkanian, H R; Hakobyan, R S; Kittel, E W; Lian Shou Liu; Metreveli, Z V; Smimova, L N; Tikhonova, L A; Tomaradze, A G; Verbeure, F; Wu Yuang Fang; Zotkin, S A

    2002-01-01

    We report results on event-by-event fluctuations of transverse momentum, Phi (p/sub t/), in pi /sup +/p and K/sup +/p collisions at 250 GeV/c. For the first time, their dependence on rapidity region, transverse momentum acceptance, multiplicity, mean transverse momentum per event, and on the correlation between transverse momentum and multiplicity are systematically presented. The results are compared with those from the PYTHIA Monte Carlo generator. The fluctuations under the same acceptance cuts as used in current heavy- ion experiments are also presented.

  4. On-chip measurements of Brownian relaxation of magnetic beads with diameters from 10 nm to 250 nm

    DEFF Research Database (Denmark)

    Østerberg, Frederik Westergaard; Rizzi, Giovanni; Hansen, Mikkel Fougt

    2013-01-01

    We demonstrate the use of planar Hall effect magnetoresistive sensors for AC susceptibility measurements of magnetic beads with frequencies ranging from DC to 1 MHz. This wide frequency range allows for measuring Brownian relaxation of magnetic beads with diameters ranging from 10 nm to 250 nm...... to sedimentation, magnetic trapping, and signal per bead. Among the investigated beads, we conclude that the beads with a nominal diameter of 80 nm are best suited for future on-chip volume-based biosensing experiments using planar Hall effect sensors....

  5. Improvement of Final Modular Exponentiation Algorithm in Tate Pairing Based on 250 Bits Modular Multiplication Platform%基于250位模乘平台的 Tate 对最终模幂算法的改进

    Institute of Scientific and Technical Information of China (English)

    王晓静

    2014-01-01

    在只支持250 bits模乘的硬件平台上,实现457 bits的二元扩域Tate对Miller算法的(双线性对的一种)最终模幂运算。在计算过程中采用一种改进的Montgomery模乘算法和中国剩余定理算法。通过具体数据实现双线性对最终模幂的运算,使用数学软件Sage来验证这种改进方案的正确性。通过理论分析和数据计算可以证明使用该方案可实现457 bits最终模幂。%The purpose of this article is to realize the 457 bits final modular exponentiation in the Tate pairing Miller algorithm ( one kind of bilinear pairings ) of binary extension field on the hardware platform which only supports 250 bits modular multiplica-tion.In the procedure of calculation , we adopted an improved Montgomery modular multiplication algorithm and Chinese remain-der theorem algorithm .The final modular exponentiation will be realized with definite data , and we will use the mathematical soft-ware Sage to verify the improved scheme .So we can prove that this scheme can realize the 457 bits final modular exponentiation through theory analysis and data calculation .

  6. Serendipitous detection of an overdensity of Herschel-SPIRE 250 micron sources south of MRC1138-26

    CERN Document Server

    Valtchanov, Ivan; Berta, S; Chapin, E; Coia, D; Conversi, L; Dannerbauer, H; Domínguez-Sánchez, H; Rawle, T D; Sánchez-Portal, M; Santos, J S; Temporin, S

    2013-01-01

    We report the serendipitous detection of a significant overdensity of Herschel-SPIRE 250 micron sources in the vicinity of MRC1138-26. We use an adaptive kernel density estimate to quantify the significance, including a comparison with other fields. The overdensity has a size of ~3.5-4' and stands out at ~5sigma with respect to the background estimate. No features with similar significance were found in four extragalactic control fields: GOODS-North, Lockman, COSMOS and UDS. The chance of having a similar overdensity in a field with the same number but randomly distributed sources is less than 2%. The clump is also visible as a low surface brightness feature in the Planck 857 GHz map. We detect 76 sources at 250 micron (with a signal-to-noise ratio greater than 3), in a region of 4' radius; 43 of those are above a flux density limit of 20 mJy. This is a factor of 3.6 in excess over the average in the four control fields, considering only the sources above 20 mJy. We also find an excess in the number counts of...

  7. Downscaling 250-m MODIS growing season NDVI based on multiple-date landsat images and data mining approaches

    Science.gov (United States)

    Gu, Yingxin; Wylie, Bruce K.

    2015-01-01

    The satellite-derived growing season time-integrated Normalized Difference Vegetation Index (GSN) has been used as a proxy for vegetation biomass productivity. The 250-m GSN data estimated from the Moderate Resolution Imaging Spectroradiometer (MODIS) sensors have been used for terrestrial ecosystem modeling and monitoring. High temporal resolution with a wide range of wavelengths make the MODIS land surface products robust and reliable. The long-term 30-m Landsat data provide spatial detailed information for characterizing human-scale processes and have been used for land cover and land change studies. The main goal of this study is to combine 250-m MODIS GSN and 30-m Landsat observations to generate a quality-improved high spatial resolution (30-m) GSN database. A rule-based piecewise regression GSN model based on MODIS and Landsat data was developed. Results show a strong correlation between predicted GSN and actual GSN (r = 0.97, average error = 0.026). The most important Landsat variables in the GSN model are Normalized Difference Vegetation Indices (NDVIs) in May and August. The derived MODIS-Landsat-based 30-m GSN map provides biophysical information for moderate-scale ecological features. This multiple sensor study retains the detailed seasonal dynamic information captured by MODIS and leverages the high-resolution information from Landsat, which will be useful for regional ecosystem studies.

  8. MONTHLY VARIABILITY OF TOTAL SUSPENDED MATTER (TSM) MAPPING USING MODIS 250M TO SUPPORT MARINE CULTURE AT MOROTAI ISLAND, NORTH MALUKU

    OpenAIRE

    KOMANG IWAN SUNIADA

    2015-01-01

    This study was conducted to provide an information of Total Suspended Matter concentration and its monthly variability using dialy data of Terra/ Aqua MOD IS level 1 b with spatial resolution 250m imagery at Morotai Island, Northern Maluku. TSM is one of the water quality key parameter to support finding suitable area which is an important step for marine culture activity. Dialy Aqua/Terra MODIS level lb, 250m dataset was downloaded freely from Goddard Space Flight Center, LAADS Web (http ://...

  9. Investigation of Normal Value of Urine Mercury among 250 Cases of Healthy People in Shijiazhuang City%石家庄市250例健康人群尿汞正常值调查

    Institute of Scientific and Technical Information of China (English)

    吴命君; 董博芳; 刘宏鹏; 王树军; 赵斐; 任清亮

    2011-01-01

    目的 了解石家庄市健康人群尿汞正常值范围.方法 采集空腹晨尿,用WS/"T97中方法测定肌酐,采用原子荧光光谱法测定尿汞.结果 石家庄市,250例健康人群尿汞正常值95%上限为14.3 μg/g肌酐;男女差异无统计学意义(P>0.05);吸烟者与总体比较,差异无统计学意义(P>0.10).结论 健康人群尿汞正常值调查为该地做好汞中毒预防和职业病诊断具有重要意义.%[Objective]To understand the normal value range of urine mercury of healthy people. [ Methods]The fasting urine sample was collected in morning, determination of creatinine and urine mercury was performed by WS/T97 and atomic fluorescence spec-trometry. [ Results]The upper limit of 95% urine mercury normal value of 250 cases healthy people in Shijiazhuang was 14.3 |xg/g creatinine; no significant difference between genders (P > 0.05) ; no significant difference existed between smokers and the overall (P >0.10). [ Conclusion]The investigation of the urine mercury normal value of healthy people has important significance in local mercury poisoning prevention and occupational disease diagnosis.

  10. 肝脂酶-250G/A基因多态性与阿尔茨海默病相关性研究%Association study of the hepatic lipase gene-250G/A promoter polymorphism and Alzheimer's disease

    Institute of Scientific and Technical Information of China (English)

    王娟; 肖志杰; 陈卫蓉

    2012-01-01

    目的:探讨常见肝脂酶启动子基因-250G/A多态性对阿尔茨海默病(AD)患者发病风险及认知功能的影响. 方法:采用病例对照研究,随机抽取湖南长沙地区汉族人群104例散发性AD患者(AD组)以及104名认知功能正常者(对照组)为研究对象,应用聚合酶链反应-限制性片段长度多态性方法测定肝脂酶-250G/A基因多态性,采用成人韦氏记忆量表(WMS)及威斯康辛卡片分类测验(WCST)进行认知功能测评. 结果:两组间GG、GA及AA 3种基因型分布差异有统计学意义(x2=7.925,P=0.019),其中AD组GG型频率显著高于对照组(27.9%和13.5%;x2 =5.233,P=0.022);GA+AA型频率显著低于对照组(72.1%和86.5%;x2=6.595,P=0.016);两组间等位基因频率比较差异无统计学意义(x2 =0.731,P>0.05).肝脂酶A等位基因携带者(GA+ AA型)WMS的短时记忆能力得分显著增高(P<0.05),而长时记忆和瞬时记忆能力得分差异无统计学意义(P>0.05).多因素Logistic回归显示,A等位基因是AD的独立保护因素之一. 结论:肝脂酶-250G/A遗传变异与AD相关,A等位基因对AD发病及短时记忆功能可能有独立保护作用.%Objective: This study aimed to assess the effect of single-nucleotide polymorphism (SNP) in the hepatic lipase (HL) promoter - 250G/A on the risk of Alzheimers disease(AD) and cognitive function. Method:Using case-control study,a total of 104 sporadic AD patients and 104 individuals without cognitive impairment from a population of Chinese Han nationality in Changsha area was studied. The polymorphism of LIPC -250G/A was determined by the restriction fragment length polymorphism (RFLP) amplified by polymerase chain reaction ( PCR) . The evaluation of cognitive function was tested by Wechsler memory scale ( WMS) and Wisconsin card sorting test(WCST). Results: There were significant differences in the frequencies of three genotypes (GG,GA and AA) between AD patients and controls(x2 = 7. 925 ,P =0

  11. CHESS Pdet-F1ow Plot诊断前列腺增生症250

    Institute of Scientific and Technical Information of China (English)

    张利国; 李雪原; 于满

    2004-01-01

    @@ 前列腺增生症是老年男性的常见病,随着中国社会人口老龄化进程的加快,前列腺增生症的发病率有增加的趋势.尿动力学之压力-流率检查是诊断前列腺增生所致膀胱流出道梗阻的金标准,对压力-流率检查的众多参数有多种分析方法,本文应用CHESS Pdet-Flow Plot诊断前列腺增生症250例,报告如下.

  12. Facebook公布四季度财报.目前拥有250万广告主

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    根据马克.扎克伯格的四季度财报电话会议,Facebook似乎在各个方面都取得了不错的增长。Facebook现在每天的视频观看时间长达1亿小时。Facebook目前拥有250万位广告主,它的主页也吸引了5000万个商家进驻,高于上季度的4500万。用户在这些主页上留下了数十亿计的评论。

  13. On artefact-free reconstruction of low-energy (30-250 eV) electron holograms

    CERN Document Server

    Latychevskaia, Tatiana; Escher, Conrad; Fink, Hans-Werner

    2013-01-01

    Low-energy electrons (30-250 eV) have been successfully employed for imaging individual biomolecules. The most simple and elegant design of a low-energy electron microscope for imaging biomolecules is a lensless setup that operates in the holographic mode. In this work we address the problem associated with the reconstruction from the recorded holograms. We discuss the twin image problem intrinsic to inline holography and the problem of the so-called biprism-like effect specific to low-energy electrons. We demonstrate how the presence of the biprism-like effect can be efficiently identified and circumvented. The presented sideband filtering reconstruction method eliminates the twin image and allows for reconstruction despite the biprism-like effect, which we demonstrate on both, simulated and experimental examples.

  14. Molecular hydrogen in the z = 2.811 absorbing material toward the quasar PKS 0528-250

    International Nuclear Information System (INIS)

    Among the previously unidentified absorbtion features in the spectrum of the quasar PKS 0528-250 obtained by previous authors tentative evidence has been found for H2 lines at the same redshift (z = 2.811) as that of the well-known absorption-line system. The column density of molecules has been estimated from the curve of growth; the fraction of H2 appears to be about 2 x 10-5. The ortho- to para-H2 ratio corresponds to the excitation temperature of Tsub(ex)(H2) = 300 +- 150 K, though the upper rotational levels J >= 3 turn out be overpopulated. The results obtained seem to provide substantial evidence for the existence of molecular hydrogen at the early cosmological epoch with z approx. 3. (author)

  15. Production of new superheavy Z=108-114 nuclei with $^{238}$U, $^{244}$Pu and $^{248,250}$Cm targets

    CERN Document Server

    Feng, Zhao-Qing; Li, Jun-Qing

    2009-01-01

    Within the framework of the dinuclear system (DNS) model, production cross sections of new superheavy nuclei with charged numbers Z=108-114 are analyzed systematically. Possible combinations based on the actinide nuclides $^{238}$U, $^{244}$Pu and $^{248,250}$Cm with the optimal excitation energies and evaporation channels are pointed out to synthesize new isotopes which lie between the nuclides produced in the cold fusion and the $^{48}$Ca induced fusion reactions experimentally, which are feasible to be constructed experimentally. It is found that the production cross sections of superheavy nuclei decrease drastically with the charged numbers of compound nuclei. Larger mass asymmetries of the entrance channels enhance the cross sections in 2n-5n channels.

  16. Utilization of the 250 kW TRIGA Mark II reactor in Ljubljana. Thirty years of experiences

    International Nuclear Information System (INIS)

    In its 30th year, the TRIGA Mark II 250 kW pulsing reactor is continuing its busy operation. With the maximum neutron flux in the central thimble of 1.1013 n/cm2 sec and many sample radiation positions the reactor has been used for a number of sophisticated experiments in the following fields: solid state physics (elastic and inelastic scattering of neutrons), neutron dosimetry, neutron radiography, reactor physics including nuclear burn up measurements and calculations and neutron activation analysis which represents one of the major usage of our reactor. Besides these, applied research around the reactor has been conducted, such as dopping of silicon monocrystals, a routine production of various radioactive isotopes for industry and medical use (18F,99mTc). At the Nuclear Training Centre the TRIGA reactor is the main teaching equipment. This training centre can fulfil the training requirements of the first Slovenian Nuclear Power Plant Krsko. (orig.)

  17. Construction and start-up of a 250 kW natural gas fueled MCFC demonstration power plant

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa, R.A.; Carter, J.; Rivera, R.; Otahal, J. [San Diego Gas & Electric, CA (United States)] [and others

    1996-12-31

    San Diego Gas & Electric (SDG&E) is participating with M-C Power in the development and commercialization program of their internally manifolded heat exchanger (IMHEX{reg_sign}) carbonate fuel cell technology. Development of the IMHEX technology base on the UNOCAL test facility resulted in the demonstration of a 250 kW thermally integrated power plant located at the Naval Air Station at Miramar, California. The members of the commercialization team lead by M-C Power (MCP) include Bechtel Corporation, Stewart & Stevenson Services, Inc., and Ishikawajima-Harima Heavy Industries (IHI). MCP produced the fuel cell stack, Bechtel was responsible for the process engineering including the control system, Stewart & Stevenson was responsible for packaging the process equipment in a skid (pumps, desulfurizer, gas heater, turbo, heat exchanger and stem generator), IHI produced a compact flat plate catalytic reformer operating on natural gas, and SDG&E assumed responsibility for plant construction, start-up and operation of the plant.

  18. A reflectivity profilometer for the optical characterisation of grade reflectivity mirrors in the 250 nm - 1100 nm spectral region

    Energy Technology Data Exchange (ETDEWEB)

    Colucci, Alessandro; Nichelatti, Enrico [ENEA, Centro Ricerche Casaccia, Rome (Italy). Dipt. Innovazione

    1998-04-01

    It`s developed the prototype of an instrument that can be used for the optical characterisation of graded reflectivity mirrors at any wavelength in the spectral region from 250 nm to 1100 nm. The instrument utilises a high-pressure Xe arc lamp as light source. Light is spectrally filtered by means of a grating monochromator. The sample is illuminated with an image of the monochromator exit slit. After reflection from the sample, this image is projected onto a 1024-elements charge-coupled device linear array driven by a digital frame board and interfaced with a personal computer. It`s tested the instrument accuracy by comparing measurement results with the corresponding ones obtained by means of a laser scanning technique. Measurement Rms repeatability has been estimated to be approximately of 0.8%. [Italiano] E` stato sviluppato il prototipo di uno strumento per la catatterizzazione ottica di specchi a riflettivita` variabile, operante a qualsiasi lunghezza d`onda nell`intervallo spettrale da 250 nm a 1100 nm. La sorgente dello strumento e` una lampada ad arco allo Xenon ad alta pressione. La luce e` filtrata spettralmente per mezzo di un monocromatore a reticolo. Il campione viene illuminato da un`immagine della fenditura d`uscita del monocromatore. Dopo essere stata riflessa dal campione, questa immagine viene proiettata su un array CCD lineare a 1024 elementi, connesso elettronicamente a una scheda digitale e interfacciato a un personal computer. L`accuratezza dello strumento e` stata verificata confrontando alcune misure con le corrispondenti misure ottenute mediante una tecnica a scansione laser. La ripetibilita` RMS delle misure e` stata stimata essere circa dello 0.8%.

  19. Two-color infrared FEL facility employing a 250-MeV Linac injector for SAGA synchrotron light source

    International Nuclear Information System (INIS)

    A two-color infrared free electron laser (FEL) facility is proposed, for which a 250-MeV linac type injector for the Saga synchrotron light source (SLS) is employed in FEL mode. The linac has two operation modes; short macropulse mode of 1 μa at 250 MeV for injection to the 1.4 GeV storage ring and long macropulse mode of 13 μs at 40 MeV for two-color infrared FEL facility, where simultaneous infrared (IR) and far-infrared (FIR) FELs are supplied for application researches by using two undulators for IR and FIR ranges like the FEL two-color FEL facility. The macropulse beam consists of a train of several ps, 0.6 nC micropulses (peak current 100A) repeating at 22.3125 or 89.25 MHz. The two-color FEL facility can supply high-power density photon beams of 10-GW/cm2 level covering an attractive wavelength range from 3.1 μm(0.4 eV) to 248 μm(0.005 eV) for scientific researches, bio-medical and industrial applications. The construction of the Saga SLS has been conducted by the Saga Prefectural Government as a six-year project started in 1998. The project is promoted by the Science and Technology Agency and the Saga Prefectural Government. The Saga SLS will be operated in 2004 to promote material science, bio-medical and industrial applications in Kyushu area. (author)

  20. Mapping Irrigated Areas Using MODIS 250 Meter Time-Series Data: A Study on Krishna River Basin (India

    Directory of Open Access Journals (Sweden)

    Andrew Nelson

    2011-01-01

    Full Text Available Mapping irrigated areas of a river basin is important in terms of assessing water use and food security. This paper describes an innovative remote sensing based vegetation phenological approach to map irrigated areas and then the differentiates the ground water irrigated areas from the surface water irrigated areas in the Krishna river basin (26,575,200 hectares in India using MODIS 250 meter every 8-day near continuous time-series data for 2000–2001. Temporal variations in the Normalized Difference Vegetation Index (NDVI pattern obtained in irrigated classes enabled demarcation between: (a irrigated surface water double crop, (b irrigated surface water continuous crop, and (c irrigated ground water mixed crops. The NDVI patterns were found to be more consistent in areas irrigated with ground water due to the continuity of water supply. Surface water availability, on the other hand, was dependent on canal water release that affected time of crop sowing and growth stages, which was in turn reflected in the NDVI pattern. Double cropped and light irrigation have relatively late onset of greenness, because they use canal water from reservoirs that drain large catchments and take weeks to fill. Minor irrigation and ground water irrigated areas have early onset of greenness because they drain smaller catchments where aquifers and reservoirs fill more quickly. Vegetation phonologies of 9 distinct classes consisting of Irrigated, rainfed, and other land use classes were also derived using MODIS 250 meter near continuous time-series data that were tested and verified using groundtruth data, Google Earth very high resolution (sub-meter to 4 meter imagery, and state-level census data. Fuzzy classification accuracies for most classes were around 80% with class mixing mainly between various irrigated classes. The areas estimated from MODIS were highly correlated with census data (R-squared value of 0.86.

  1. Experimental study on dynamic behavior of 200 ~ 250km/h high-speed railway bridges%时速200~250km高速铁路桥梁动力性能试验研究

    Institute of Scientific and Technical Information of China (English)

    刘鹏辉; 姚京川; 尹京; 董振升; 孟鑫; 杨宜谦

    2013-01-01

    基于近年来在我国开展的多条高速铁路桥梁动力性能试验研究,对设计速度200~250km/h的常用跨度简支梁桥以及连续梁桥的自振特性、刚度参数、梁体动力响应以及动车组通过桥梁时的安全性和平稳性试验结果进行系统总结和规律分析,研究结果表明:①高速铁路桥梁具有足够的竖、横向刚度,能够满足动车组200 ~ 250km/h高速运行要求;②现有高速铁路设计规范通过控制简支梁的竖向自振频率,避开了由移动荷载列对桥梁产生的竖向加载频率,有效控制了梁体竖向共振发生,但在特定车速下会产生超谐共振;③常用跨度混凝土简支梁横向自振频率与列车横向强振频率相差较远,不会产生横向共振现象;④在现有桥梁刚度条件下,连续等跨布置简支梁对高速动车组的运行安全性和平稳性没有影响.%Based on the recent experimental research results on dynamic behavior of many high-speed railway bridges in China, the results of common-span simply-supported beams and continuous beams are summarized and analyzed. The research indexes include natural characteristics, stiffness parameters, dynamic responses of beam, security and stationarity of multiple unit when passing the bridge. Following results can be shown; (1) the vertical and lateral rigidity of high-speed railway bridges is sufficient to meet the requirements of running speeds between 200km/h and 250km/h. (2 ) in the code for design of high speed railway bridges, vertical natural frequency is defined strictly to keep away from forced frequency of moving load, therefore beam resonance is restricted effectively. However, the superharmonic resonance will appear at particular velocity. (3 ) for concrete simply-supported beams with common spans, the lateral natural frequency is far from the forced frequency and the lateral resonance cannot appear. (4) the continuous equal span arrangement of simple supported beams

  2. MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process

    Science.gov (United States)

    Huang, Hao; Zhou, Xin; Liu, Xi; Xu, Tao; Ma, Limin

    2016-01-01

    Increasing evidence suggests that epilepsy is the result of synaptic reorganization and pathological excitatory loop formation in the central nervous system; however, the mechanisms that regulate this process are not well understood. We proposed that microRNA-132 (miR-132) and p250GAP might play important roles in this process by activating the downstream Rho GTPase family. We tested this hypothesis using a magnesium-free medium-induced epileptic model of cultured hippocampal neurons. We investigated whether miR-132 regulates GTPase activity through p250GAP and found that Cdc42 was significantly activated in our experimental model. Silencing miR-132 inhibited the electrical excitability level of cultured epileptic neurons, whereas silencing p250GAP had an opposite effect. In addition, we verified the effect of miR-132 in vivo and found that silencing miR-132 inhibited the aberrant formation of dendritic spines and chronic spontaneous seizure in a lithium-pilocarpine-induced epileptic mouse model. Finally, we confirmed that silencing miR-132 has a neuroprotective effect on cultured epileptic neurons; however, this effect did not occur through the p250GAP pathway. Generally, silencing miR-132 may suppress spontaneous seizure activity through the miR-132/p250GAP/Cdc42 pathway by regulating the morphology and electrophysiology of dendritic spines; therefore, miR-132 may serve as a potential target for the development of antiepileptic drugs.

  3. MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process.

    Science.gov (United States)

    Yuan, Jinxian; Huang, Hao; Zhou, Xin; Liu, Xi; Ou, Shu; Xu, Tao; Li, Ruohan; Ma, Limin; Chen, Yangmei

    2016-01-01

    Increasing evidence suggests that epilepsy is the result of synaptic reorganization and pathological excitatory loop formation in the central nervous system; however, the mechanisms that regulate this process are not well understood. We proposed that microRNA-132 (miR-132) and p250GAP might play important roles in this process by activating the downstream Rho GTPase family. We tested this hypothesis using a magnesium-free medium-induced epileptic model of cultured hippocampal neurons. We investigated whether miR-132 regulates GTPase activity through p250GAP and found that Cdc42 was significantly activated in our experimental model. Silencing miR-132 inhibited the electrical excitability level of cultured epileptic neurons, whereas silencing p250GAP had an opposite effect. In addition, we verified the effect of miR-132 in vivo and found that silencing miR-132 inhibited the aberrant formation of dendritic spines and chronic spontaneous seizure in a lithium-pilocarpine-induced epileptic mouse model. Finally, we confirmed that silencing miR-132 has a neuroprotective effect on cultured epileptic neurons; however, this effect did not occur through the p250GAP pathway. Generally, silencing miR-132 may suppress spontaneous seizure activity through the miR-132/p250GAP/Cdc42 pathway by regulating the morphology and electrophysiology of dendritic spines; therefore, miR-132 may serve as a potential target for the development of antiepileptic drugs. PMID:27579184

  4. 水平连铸灰铁HT250型材的阻尼行为%Damping Behavior of Grey Cast Iron HT250 Dense Bar Fabricated by Horizontal Continuous Casting

    Institute of Scientific and Technical Information of China (English)

    张忠明; 王锦程; 马莹; 李伟明; 徐春杰; 王刚

    2012-01-01

    选用直径为55 mm的水平连铸灰铁HT250棒材,利用动态热机械分析仪测试型材的阻尼性能随振幅、频率和温度的变化关系,探讨灰铸铁型材的阻尼机制.研究表明,灰铸铁型材的阻尼性能随振幅和频率的提高而增加.在40℃附近出现斯诺克温度内耗峰.斯诺克峰的出现,使型材的阻尼性能随温度的变化在高低温时表现出完全不同的趋势.存在一临界应变振幅范围,大应变振幅下的阻尼性能远高于小应变振幅下的阻尼性能.灰铸铁型材的阻尼温度效应主要来源于点缺陷阻尼.位错阻尼在阻尼频率效应和阻尼振幅效应中起了主导作用,决定了型材的阻尼-频率行为和阻尼振幅行为.%The variation of damping behavior with vibration amplitude, frequency and temperature in grey cast iron HT250 dense bar produced by horizontal continuous casting was measured by dynamic mechanical analyzer to understand the damping mechanism of the alloy. The results show that the damping behavior is increased with increasing in amplitude and frequency. An internal friction peak occurs at about 40 "C and is extrapolated by Snoek relaxation. The damping temperature curve shows inverse tendencies at higher temperature range and lower temperature range as a result of the occurrence of Snoek peak. There exists a critical amplitude range, and the damping behavior at higher amplitude is much higher than that at lower amplitude. The temperature-dependent damping capacity mainly is resulted from point-defect damping, while dislocation damping is predominant in the frequency-dependent damping and amplitude-dependent damping, which controls the damping behavior of the alloy.

  5. Hydrological variability in the Northern Levant: a 250 ka multiproxy record from the Yammoûneh (Lebanon sedimentary sequence

    Directory of Open Access Journals (Sweden)

    F. Gasse

    2011-11-01

    Full Text Available The Levant is a key region in terms of both long-term hydroclimate dynamics and human cultural evolution. Our understanding of the regional response to glacial-interglacial boundary conditions is limited by uncertainties in proxy-data interpretation and the lack of long-term records from different geographical settings.

    The present paper provides a 250 ka paleoenvironmental reconstruction based on a multi-proxy approach from northern Levant, derived from a 36 m lacustrine-palustrine sequence cored in the small intra-mountainous karstic Yammoûneh basin from northern Lebanon. We combined time series of sediment properties, paleovegetation, and carbonate oxygen isotopes (δc, to yield a comprehensive view of paleohydrologic-paleoclimatic fluctuations in the basin over the two last glacial-interglacial cycles. Integration of all available proxies shows that Interglacial maxima (early-mid MIS 7, MIS 5.5 and early MIS 1 experienced relatively high effective moisture, evidenced by the dominance of forested landscapes (although with different forest types associated with authigenic carbonate sedimentation in a productive waterbody. Synchronous and steep δc increases can be reconciled with enhanced mean annual moisture when changes in seasonality are taken into account. During Glacials periods (MIS 2 and MIS 6, open vegetation tends to replace the forests, favouring local erosion and detrital sedimentation. However, all proxy data reveal an overall wetting during MIS 6, while a drying trend took place during MIS4-2, leading to extremely harsh LGM conditions possibly linked to water storage as ice in the surrounding highlands. Over the past 250 ka, the Yammoûneh record shows an overall decrease in local effective water, coincident with a weakening of seasonal insolation contrasts linked to the decreasing amplitude of the eccentricity cycle.

    The Yammoûneh record is roughly consistent with long-term climatic

  6. Fission cross section measurements of Cm-247, Cf-250 and Es-254 from 0.1 eV to 80 keV

    International Nuclear Information System (INIS)

    Fission cross section measurements were made with the RINS system over the neutron energy range from approximately 0.1 eV to 80 keV upon samples of Cm-247, Cf-250 and Es-254. The Cm-247 measurement was undertaken to complete the RINS fission cross section measurement sequence of the curium isotopes, Es-254 was measured because it is a very heavy odd-odd nucleus which might show interesting nuclear structure effects in its fission cross section, and Cf-250 was measured to account for its buildup as a daughter product from the 276-day halflife Es-254. 6 refs., 3 figs

  7. A low power time-interleaved 10-bit 250-MSPS charge domain pipelined ADC for IF sampling

    Institute of Scientific and Technical Information of China (English)

    Chen Zhenhai; Qian Hongwen; Huang Songren; Zhang Hong; Yu Zongguang

    2013-01-01

    A 10-bit 250-MSPS two-channel time-interleaved charge-domain (CD) pipelined analog-to-digital converter (ADC) is presented.MOS bucket-brigade device (BBD) based CD pipelined architecture is used to achieve low power consumption.An all digital low power DLL is used to alleviate the timing mismatches and to reduce the aperture jitter.A new bootstrapped MOS switch is designed in the sample and hold circuit to enhance the IF sampling capability.The ADC achieves a spurious free dynamic range (SFDR) of 67.1 dB,signal-to-noise ratio (SNDR) of 55.1 dB for a 10.1 MHz input,and SFDR of 61.6 dB,SNDR of 52.6 dB for a 355 MHz input at full sampling rate.Differential nonlinearity (DNL) is +0.5/-0.4 LSB and integral nonlinearity (INL) is +0.8/-0.75LSB.Fabricated in a 0.18-μm 1P6M CMOS process,the prototype 10-bit pipelined ADC occupies 1.8 × 1.3 mm2of active die area,and consumes only 68 mW at 1.8 V supply.

  8. A 10-bit 250 MSPS charge-domain pipelined ADC with replica controlled PVT insensitive BCT circuit

    Science.gov (United States)

    Songren, Huang; Hong, Zhang; Zhenhai, Chen; Shuang, Zhu; Zongguang, Yu; Hongwen, Qian; Yue, Hao

    2015-05-01

    A low power 10-bit 250 MSPS charge-domain (CD) pipelined analog-to-digital converter (ADC) is introduced. The ADC is implemented in MOS bucket-brigade devices (BBDs) based CD pipelined architecture. A replica controlled boosted charge transfer (BCT) circuit is introduced to reject the influence of PVT variations on the charge transfer process. Based on replica controlled BCT, the CD pipelined ADC is designed and realized in a 1P6M 0.18 μm CMOS process. The ADC achieves an SFDR of 64.4 dB, an SNDR of 56.9 dB and an ENOB of 9.2 for a 9.9 MHz input; and an SFDR of 63.1 dB, an SNR of 55.2 dB, an SNDR of 54.5 dB and an ENOB of 8.7 for a 220.5 MHz input at full sampling rate. The DNL is +0.5/ -0.55 LSB and INL is +0.8/ -0.85 LSB. The power consumption of the prototype ADC is only 45 mW at 1.8 V supply and it occupies an active die area of 1.56 mm2. Project supported by the National Natural Science Foundation of China (No. 61106027).

  9. Personal dose equivalent conversion coefficients for neutron fluence over the energy range of 20 to 250 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Mclean, Thomas D [Los Alamos National Laboratory; Justus, Alan L [Los Alamos National Laboratory; Gadd, S Milan [Los Alamos National Laboratory; Olsher, Richard H [RP-2; Devine, Robert T [RP-2

    2009-01-01

    Monte Carlo simulations were performed to extend existing neutron personal dose equivalent fluence-to-dose conversion coefficients to an energy of 250 MeV. Presently, conversion coefficients, H(p,slab)(10,alpha)/Phi, are given by ICRP-74 and ICRU-57 for a range of angles of radiation incidence (alpha = 0, 15, 30, 45, 60 and 75 degrees ) in the energy range from thermal to 20 MeV. Standard practice has been to base operational dose quantity calculations <20 MeV on the kerma approximation, which assumes that charged particle secondaries are locally deposited, or at least that charged particle equilibrium exists within the tally cell volume. However, with increasing neutron energy the kerma approximation may no longer be valid for some energetic secondaries such as protons. The Los Alamos Monte Carlo radiation transport code MCNPX was used for all absorbed dose calculations. Transport models and collision-based energy deposition tallies were used for neutron energies >20 MeV. Both light and heavy ions (HIs) (carbon, nitrogen and oxygen recoil nuclei) were transported down to a lower energy limit (1 keV for light ions and 5 MeV for HIs). Track energy below the limit was assumed to be locally deposited. For neutron tracks <20 MeV, kerma factors were used to obtain absorbed dose. Results are presented for a discrete set of angles of incidence on an ICRU tissue slab phantom.

  10. Evolution of Ti-Based Nonmetallic Inclusions During Solution Treatment of Maraging 250 Steel: Thermodynamic Calculations and Experimental Verification

    Science.gov (United States)

    Shmulevitsh, Mati; Pinkas, Malki; Weizman, Amir; Frage, Nachum

    2011-06-01

    The evolution of Ti-based nonmetallic inclusions in Maraging 250 steel, namely Ti(CxN1-x) and Ti4C2S2, was investigated experimentally. Their stability in austenite also was analyzed by a thermodynamic analysis of the Fe-Ni-Ti-C-N-S system. It was established that the total concentration of the inclusions decreases from 0.024 pct to 0.008 pct after treatment at 1453 K (1180 °C) for 3 hours. The Ti4C2S2 inclusions completely dissolve in austenite at 1523 K (1250 °C) during 1 hour of treatment. The composition of the carbonitride inclusions is shifted toward higher TiN contents when they dissolve in austenite. Nitrogen-enriched titanium carbonitride inclusions are stable in austenite and their fraction may be reduced only by controlling nitrogen content in the steel. The experimental observations are in good agreement with the results of the thermodynamic analysis.

  11. Growth characteristics of amorphous-layer-free nanocrystalline silicon films fabricated by very high frequency PECVD at 250

    Institute of Scientific and Technical Information of China (English)

    Guo Yan-Qing; Huang Rui; Song Jie; Wang Xiang; Song Chao; Zhang Yi-Xiong

    2012-01-01

    Amorphous-layer-free nanocrystalline silicon films were prepared by a very high frequency plasma enhanced chemical vapor deposition (PECVD) technique using hydrogen-diluted SiH4 at 250 ℃.The dependence of the crystallinity of the film on the hydrogen dilution ratio and the film thickness was investigated.Raman spectra show that the thickness of the initial amorphous incubation layer on silicon oxide gradually decreases with increasing hydrogen dilution ratio.High-resolution transmission electron microscopy reveals that the initial amorphous incubation layer can be completely eliminated at a hydrogen dilution ratio of 98%,which is lower than that needed for the growth of amorphous-layer-free nanocrystalline silicon using an excitation frequency of 13.56 MHz.More studies on the microstructure evolution of the initial amorphous incubation layer with hydrogen dilution ratios were performed using Fourier-transform infrared spectroscopy.It is suggested that the high hydrogen dilution,as well as the higher plasma excitation frequency,plays an important role in the formation of amorphous-layer-free nanocrystalline silicon films.

  12. Phase Equilibria of the Ternary Sn-Zn-Co System at 250°C and 500°C

    Science.gov (United States)

    Wang, Chao-hong; Huang, Sheng-en; Huang, Po-yen

    2015-12-01

    The isothermal sections of the ternary Sn-Zn-Co system (IMCs) are very limited. For the phase equilibria at 250°C, two ternary IMCs, T1 and T2, were found, whose compositions were Sn-25 at.%Zn-25 at.%Co and Sn-15 at.%Zn-41 at.%Co, respectively. For the phase equilibria at 500°C, in addition to the T2 phase, another ternary IMC, namely T3 (Sn-18 at.%Zn-37 at.%Co), was also found. Moreover, the phase stability of the T1 and T3 phases was investigated at temperatures of 260°C to 400°C in detail. The equilibrium phase was the T1 phase below 300°C, and changed to the T3 phase at 400°C. The crystal structures of these three ternary IMCs were also studied. The T1 phase has a cubic structure ( Pm3m), and the T2 and T3 phases are orthorhombic in space group Cmcm and Pnma, respectively.

  13. Formation of Super-Earth Mass Planets at 125-250 AU from a Solar-type Star

    CERN Document Server

    Kenyon, S J

    2015-01-01

    We investigate pathways for the formation of icy super-Earth mass planets orbiting at 125-250 AU around a 1 solar mass star. An extensive suite of coagulation calculations demonstrates that swarms of 1 cm to 10 m planetesimals can form super-Earth mass planets on time scales of 1-3 Gyr. Collisional damping of 0.01-100 cm particles during oligarchic growth is a highlight of these simulations. In some situations, damping initiates a second runaway growth phase where 100-3000 km protoplanets grow to super-Earth sizes. Our results establish the initial conditions and physical processes required for in situ formation of super-Earth planets at large distances from the host star. For nearby dusty disks in HD 107146, HD 202628, and HD 207129, ongoing super-Earth formation at 80-150 AU could produce gaps and other structures in the debris. In the solar system, forming a putative planet X at a 1000 AU) requires a modest (very massive) protosolar nebula.

  14. Formation of Super-Earth Mass Planets at 125–250 AU from a Solar-type Star

    Science.gov (United States)

    Kenyon, Scott J.; Bromley, Benjamin C.

    2015-06-01

    We investigate pathways for the formation of icy super-Earth mass planets orbiting at 125–250 AU around a 1 {{M}ȯ } star. An extensive suite of coagulation calculations demonstrates that swarms of 1 cm–10 m planetesimals can form super-Earth mass planets on timescales of 1–3 Gyr. Collisional damping of 10‑2‑102 cm particles during oligarchic growth is a highlight of these simulations. In some situations, damping initiates a second runaway growth phase where 1000–3000 km protoplanets grow to super-Earth sizes. Our results establish the initial conditions and physical processes required for in situ formation of super-Earth planets at large distances from the host star. For nearby dusty disks in HD 107146, HD 202628, and HD 207129, ongoing super-Earth formation at 80–150 AU could produce gaps and other structures in the debris. In the solar system, forming a putative planet X at a≲ 300 AU (a≳ 1000 AU) requires a modest (very massive) protosolar nebula.

  15. Mapping grassland productivity with 250-m eMODIS NDVI and SSURGO database over the Greater Platte River Basin, USA

    Science.gov (United States)

    Gu, Yingxin; Wylie, Bruce K.; Bliss, Norman B.

    2013-01-01

    This study assessed and described a relationship between satellite-derived growing season averaged Normalized Difference Vegetation Index (NDVI) and annual productivity for grasslands within the Greater Platte River Basin (GPRB) of the United States. We compared growing season averaged NDVI (GSN) with Soil Survey Geographic (SSURGO) database rangeland productivity and flux tower Gross Primary Productivity (GPP) for grassland areas. The GSN was calculated for each of nine years (2000–2008) using the 7-day composite 250-m eMODIS (expedited Moderate Resolution Imaging Spectroradiometer) NDVI data. Strong correlations exist between the nine-year mean GSN (MGSN) and SSURGO annual productivity for grasslands (R2 = 0.74 for approximately 8000 pixels randomly selected from eight homogeneous regions within the GPRB; R2 = 0.96 for the 14 cluster-averaged points). Results also reveal a strong correlation between GSN and flux tower growing season averaged GPP (R2 = 0.71). Finally, we developed an empirical equation to estimate grassland productivity based on the MGSN. Spatially explicit estimates of grassland productivity over the GPRB were generated, which improved the regional consistency of SSURGO grassland productivity data and can help scientists and land managers to better understand the actual biophysical and ecological characteristics of grassland systems in the GPRB. This final estimated grassland production map can also be used as an input for biogeochemical, ecological, and climate change models.

  16. Modeling the surface complexation of calcium at the rutile-water interface to 250°C

    Science.gov (United States)

    Ridley, Moira K.; Machesky, Michael L.; Wesolowski, David J.; Palmer, Donald A.

    2004-01-01

    The adsorption behavior of metal-(hydr)oxide surfaces can be described and rationalized using a variety of surface complexation models. However, these models do not uniquely describe experimental data unless some additional insight into actual binding mechanisms for a given system is available. This paper presents the results of applying the MUlti SIte Complexation or MUSIC model, coupled with a Stern-based three layer description of the electric double layer, to Ca 2+ adsorption data on rutile surfaces from 25 to 250°C in 0.03 and 0.30 m NaCl background electrolyte. Model results reveal that the tetradentate adsorption configuration found for Sr 2+ adsorbed on the rutile (110) surface in the in situ X-ray standing wave experiments of Fenter et al. (2000) provides a good fit to all Ca 2+ adsorption data. Furthermore, it is also shown that equally good fits result from other plausible adsorption complexes, including various monodentate and bidentate adsorption configurations. These results amply demonstrate the utility of in situ spectroscopic data to constrain surface complexation modeling, and the ability of the MUSIC model approach to accommodate this spectroscopic information. Moreover, this is the first use of any surface complexation model to describe multivalent ion adsorption systematically into the hydrothermal regime.

  17. N250r and N400 ERP correlates of immediate famous face repetition are independent of perceptual load.

    Science.gov (United States)

    Neumann, Markus F; Schweinberger, Stefan R

    2008-11-01

    It is a matter of considerable debate whether attention to initial stimulus presentations is required for repetition-related neural modulations to occur. Recently, it has been assumed that faces are particularly hard to ignore, and can capture attention in a reflexive manner. In line with this idea, electrophysiological evidence for long-term repetition effects of unattended famous faces has been reported. The present study investigated influences of attention to prime faces on short-term repetition effects in event-related potentials (ERPs). We manipulated attention to short (200 ms) prime presentations (S1) of task-irrelevant famous faces according to Lavie's Perceptual Load Theory. Participants attended to letter strings superimposed on face images, and identified target letters "X" vs. "N" embedded in strings of either 6 different (high load) or 6 identical (low load) letters. Letter identification was followed by probe presentations (S2), which were either repetitions of S1 faces, new famous faces, or infrequent butterflies, to which participants responded. Our ERP data revealed repetition effects in terms of an N250r at occipito-temporal regions, suggesting priming of face identification processes, and in terms of an N400 at the vertex, suggesting semantic priming. Crucially, the magnitude of these effects was unaffected by perceptual load at S1 presentation. This indicates that task-irrelevant face processing is remarkably preserved even in a demanding letter detection task, supporting recent notions of face-specific attentional resources. PMID:18793621

  18. A 250 frames-per-second 640 by 480 pixel division-of-focal-plane polarimeter for the visible spectrum

    Science.gov (United States)

    York, Timothy; Marinov, Radoslav; Gruev, Viktor

    2014-05-01

    The most common method of polarimetery involves imaging a scene through a polarization analyzer at multiple configurations. Switching among these configurations requires capturing multiple images of the scene, limiting the ability to capture real-time polarization data due to multiple scene sampling and motion artifacts. Advances in nanofabrication technology have allowed direct integration of polarization analyzers onto the sensor, enabling the capture of multiple analyzer intensities from a single frame. Using this technique, we have fabricated a high frame rate, VGA resolution, division of focal plane polarization imager for the visible spectrum. The imaging sensor is realized by monolithic integration of aluminum nanowires with an array of CCD imaging elements. The pixelated nanowire polarization filters are at four different orientations offset by 45° This allows for recording of the first three Stokes parameters at every super pixel, and subsequently the degree of linear polarization and angle of polarization are computed at 250 frames per second at full VGA resolution and over 1000 when limited to a subsection of the array. The imaging sensor also employs a per pixel calibration scheme which mitigates the variations in the aluminum nanowire sizes. We present an optical characterization of the sensor, and then utilize the increased frame rate to capture high speed polarization images of pieces of polycarbonate plastic placed under stress. The high frame rate allows us to recover strain information that regular rate sensors cannot.

  19. Comparison of PCBBs and CTs irradiated at 250 deg. C, 300 deg. C, and 350 deg. C

    Energy Technology Data Exchange (ETDEWEB)

    Rensman, J.; Nolles, H.N. [ECN-Energy Research Foundation, Research Unit NRG, Westerduinweg, Petten (Netherlands); Lucon, E. [SCK-CEN, Institute of Nuclear Material Science, Boeretang, Mol (Belgium); Spatig, P. [EPFL-CRDP, Centre de Recherches en Physique des Plasmas, Association Euratom-Confederation Suisse, CH Villigen PSI (Switzerland)

    2007-07-01

    Full text of publication follows: The fracture toughness of irradiated Eurofer steel is difficult to characterise. Several limitations are identified in this paper with respect to the conventional treatment of fracture data of BCC steels in the transition region. It is uncertain that the RPV Master Curve is applicable to unirradiated Eurofer, and low temperature irradiation adds more to this uncertainty. The lack of strain hardening and the dose variation within each batch are two complicating factors. An irradiation has been carried out in the BFR up to a nominal dose of 2.5 dpa at 250 deg. C, 300 deg. C, and 350 deg. C in sodium. Twelve small size pre-cracked bend specimens and eight mini-CT specimens have been irradiated in each temperature section. We analyse the effect of constraint and censoring limit, and the specimen geometry and loading configuration. The fracture data are treated in several ways that are proposed in open literature to investigate the effect of irradiation on a reference temperature like the ASTM E1921 T0. In addition, the relation between the tensile hardening, which is presented in a companion paper, and the shift calculated with the various methods is studied. (authors)

  20. VBFNLO. A patron level Monte Carlo for processes with electroweak bosons. Manual for Version 2.5.0

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, K.; Bellm, J. [Karlsruhe Institute of Technology, Karlsruhe (Germany). Inst. fuer Theoretische Physik; Bozzi, G. [Milano-Bicocca Univ. (Italy). Dipt. di Fisica; INFN, Sezione di Milano-Bicocca (IT)] (and others)

    2011-08-15

    VBFNLO is a flexible parton level Monte Carlo program for the simulation of vector boson fusion, double and triple vector boson production in hadronic collisions at next-to-leading order (NLO) in the strong coupling constant, as well as Higgs boson plus two jet production via gluon fusion at the one-loop level. In the new release - Version 2.5.0 - several new processes have been added at NLO QCD: vector boson fusion production of a Higgs boson plus a photon, vector boson fusion production of a photon, W{gamma} and WZ production plus a hadronic jet and the triboson production processes WW{gamma}, ZZ{gamma}, WZ{gamma}, W{gamma}{gamma}, Z{gamma}{gamma} and {gamma}{gamma}{gamma}. The code has been extended to run in the Minimal Supersymmetric Standard Model (MSSM), and electroweak corrections to Higgs boson production via weak boson fusion have been included. Anomalous gauge boson couplings can be used in new processes and the Three-Site Higgsless model has been implemented for several processes. The simulation of Higgs boson production via gluon fusion has been improved. (orig.)

  1. Effect of Tube Spinning With Performance and Microstructure Subsequent Heat-Treatment on Evolution of T250 Maraging Steel

    Institute of Scientific and Technical Information of China (English)

    HU Zheng-fei; WANG Chun-xu

    2012-01-01

    The effects of spinning deformation and subsequent heat treatments on the mechanical properties and microstructure of 18Ni Co-free Maraging steel (T250) tube were evaluated comparatively with the perform. An obvious radial shrinkage is detected in spun tubes after heat treatment and the magnitude of the shrinkage induced by solution treatment is almost the same as that by aging. Plastic deformation during spinning elongated the grains severely in the direction of metal flow. The solution treatment resulted in a drastically refined grain and recrystallised microstructure, removing the effect of plastic deformation, relieving the tangential residual stress and strain and improving hardness. Subsequent aging obtained a tempered microstructure, enhancing hardness values strikingly for precipitation strengthening. XRD (X-ray diffraction) analysis indicated that the reversed austenite formed in a plate-like along the grain boundaries and the volume fraction of austenite in spun tube was more than double that in the preform. These results imply that the residual stress and stain induced by spinning process and reversed austenite forming during aging might have the similar contribution to the radical shrinkage.

  2. A gas/liquid chromatographic-mass spectrometric method for the rapid screening of 250 pesticides in aqueous matrices

    Energy Technology Data Exchange (ETDEWEB)

    Chandramouli, B.; Harvan, D.; Brittain, S.; Hass, R. [Eno River Labs, LLC. Durham, NC (United States)

    2004-09-15

    Pesticide residues in food present a potentially serious and significant cause for concern. Many pesticides have been associated with significant health effects to the nervous and endocrine systems and some have been deemed carcinogenic. There are many well-established techniques for pesticide analysis. However, commercial pesticide methods have traditionally only been available for specific pesticide families, such as chlorinated pesticides or herbicides, and at detection limits ranging from 0.05 ppb to 1 ppm in aqueous matrices. Techniques that can quickly screen for the presence/absence of pesticide residues in food matrices are critical in ensuring the safety of food and water. This paper outlines a combined Gas Chromatographic-High Resolution Mass Spectrometric (GC-HRMS) and Liquid Chromatographic Tandem Mass Spectrometric (LC-MS/MS) screening assay for 250 pesticides that was developed for use in water, and soda samples at screening levels ranging from 0.1-5 ppb. The pesticides selected have been identified by the European Union as being of concern and the target of possible legislation. The list encompasses a variety of pesticide classes and compound groupings.

  3. A fuel cell operating between room temperature and 250 C based on a new phosphoric acid based composite electrolyte

    Energy Technology Data Exchange (ETDEWEB)

    Lan, Rong [Department of Chemistry, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); Xu, Xiaoxiang; Irvine, John T.S. [School of Chemistry, University of St Andrews, St Andrews, Fife KY16 9ST (United Kingdom); Tao, Shanwen [Department of Chemistry, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom); School of Chemistry, University of St Andrews, St Andrews, Fife KY16 9ST (United Kingdom)

    2010-10-15

    A phosphoric acid based composite material with core-shell microstructure has been developed to be used as a new electrolyte for fuel cells. A fuel cell based on this electrolyte can operate at room temperature indicating leaching of H{sub 3}PO{sub 4} with liquid water is insignificant at room temperature. This will help to improve the thermal cyclability of phosphoric acid based electrolyte to make it easier for practical use. The conductivity of this H{sub 3}PO{sub 4}-based electrolyte is stable at 250 C with addition of the hydrophilic inorganic compound BPO{sub 4} forming a core-shell microstructure which makes it possible to run a PAFC at a temperature above 200 C. The core-shell microstructure retains after the fuel cell measurements. A power density of 350 mW/cm{sup 2} for a H{sub 2}/O{sub 2} fuel cell has been achieved at 200 C. The increase in operating temperature does not have significant benefit to the performance of a H{sub 2}/O{sub 2} fuel cell. For the first time, a composite electrolyte material for phosphoric acid fuel cells which can operate in a wide range of temperature has been evaluated but certainly further investigation is required. (author)

  4. On artefact-free reconstruction of low-energy (30–250 eV) electron holograms

    Energy Technology Data Exchange (ETDEWEB)

    Latychevskaia, Tatiana, E-mail: tatiana@physik.uzh.ch; Longchamp, Jean-Nicolas; Escher, Conrad; Fink, Hans-Werner

    2014-10-15

    Low-energy electrons (30–250 eV) have been successfully employed for imaging individual biomolecules. The most simple and elegant design of a low-energy electron microscope for imaging biomolecules is a lensless setup that operates in the holographic mode. In this work we address the problem associated with the reconstruction from the recorded holograms. We discuss the twin image problem intrinsic to inline holography and the problem of the so-called biprism-like effect specific to low-energy electrons. We demonstrate how the presence of the biprism-like effect can be efficiently identified and circumvented. The presented sideband filtering reconstruction method eliminates the twin image and allows for reconstruction despite the biprism-like effect, which we demonstrate on both, simulated and experimental examples. - Highlights: • Radiation damage-free imaging of individual biomolecules. • Elimination of the twin image in inline holograms. • Circumventing biprism-like effect in low-energy electron holograms. • Artefact-free reconstructions of low-energy electron holograms.

  5. Biometric Calculation and Refractive Results. A Study of 250 Cases of Patients Operated for Cataract Cálculo biométrico y resultados refractivos. Estudio de 250 casos operados de catarata

    Directory of Open Access Journals (Sweden)

    Inés Benita Zamora Galindo

    2012-02-01

    Full Text Available

    Fundamento: el implante de lentes intraoculares en la cirugía de catarata significa un avance en la corrección refractiva de la afaquia. Pero sin el estudio previo a la cirugía y el correcto cálculo de la lente intraocular, los resultados no serían satisfactorios. Objetivo: evaluar el cálculo biométrico y la refracción posquirúrgica de pacientes operados de cataratas. Metodos: estudio descriptivo realizado en el Centro de Oftalmología del Estado de Anzoátegui, Venezuela, que incluyó 250 pacientes sometidos a cirugía de catarata, a quienes previamente se les realizó refracción, queratometría, biometría y cálculo de lente intraocular. Después de la cirugía se determinó: refracción esperada por el cálculo biométrico, error refractivo posoperatorio, agudeza visual posquirúrgica sin corrección y con corrección. Resultados: predominó el sexo femenino y el grupo de edad entre 60 y 69 años. El valor más registrado de la queratometría  osciló de 43 a 44 dioptrías. El valor de la longitud axial más destacado fue de 22 a 24 mm. Las lentes intraoculares más usadas fueron de 16 a 20 dioptrías y las de 21 a 25 dioptrías. El mayor por ciento de la refracción esperada estuvo en el grupo de 0,00 a 0, 50. El error refractivo que predominó fue el de 0,50 a 1,00. En la refracción realizada al mes de la cirugía, sin cristales, más de la mitad de los pacientes obtuvo visiones entre 20/30 y 20/25. Conclusiones: se demostró la efectividad del cálculo de la lente intraocular previo a la cirugía de catarata.

    Background: the implantation of intraocular lenses in cataract surgery represents a step forward in refractive correction of aphakia. Nevertheless, without a study prior to surgery and the correct calculation of the intraocular lens, the results would not be satisfactory.

  6. Evaluation of mechanical properties of Z250 composite resin light-cured by different methods Avaliação de propriedades mecânicas da resina composta Z250 fotoativada com diferentes métodos

    Directory of Open Access Journals (Sweden)

    Andresa Carla Obici

    2005-12-01

    Full Text Available This study evaluated some mechanical parameters of Z250 composite resin using different light-curing methods. Ten specimens were prepared for each mechanical test group with different dimensions according to the test. Light-curing was performed by: a. continuous light (800mW/cm²-40s; b. exponential light (0-800mW/cm²-40s; c. intermittent light (2s-600mW/cm²; 2s without light-80s; d. stepped light (10s-150mW/cm²; 30s-650mW/cm²; e. PAC (1320mW/cm²-3s; f. LED (350mW/cm²-40s. After 24 ± 1 h, the specimens were loaded at a crosshead speed of 0.5 mm/min until fracture. The mechanical properties were calculated and analyzed by ANOVA and Tukey test (5%. The results showed that the highest compressive strength values were found for the continuous, exponential, intermittent and stepped light methods, whereas PAC and LED obtained the lowest values. LED, stepped light, PAC, exponential and continuous light presented the highest values for diametral tensile strength. The intermittent light showed the lowest value, which was significantly lower than the value obtained for LED only. Flexural strength results were not significantly different between all light-curing methods. Finally, the highest modulus of elasticity values were obtained for LED, exponential, continuous and intermittent light, whereas PAC and stepped light showed the lowest values. The mechanical properties were affected by light-curing methods employed.Este estudo avaliou algumas propriedades mecânicas da resina composta Z250 usando diferentes métodos de fotoativação. Dez amostras foram preparadas para cada grupo, com diferentes dimensões de acordo com o ensaio. Os métodos de fotoativação foram: a luz contínua (800mW/cm²-40s; b luz exponencial (0-800mW/cm²-40s; c luz intermitente (2s-600mW/cm²; 2s sem luz-80s; d dupla intensidade (10s-150mW/cm²; 30s-650mW/cm²; e PAC (1320mW/cm²-3s; f LED (350mW/cm²-40s. Após 24 ± 1 h, as amostras foram carregadas até fraturar (v=0

  7. 时速250km以上高速列车制动模式曲线算法%Braking mode curve arithmetic of high-speed train above 250 km · h-1

    Institute of Scientific and Technical Information of China (English)

    上官伟; 蔡伯根; 王晶晶; 王剑; 王利

    2011-01-01

    The braking system of high-speed train above 250 km ? H-1 was studied, and the running resistance, braking force and braking distance of high-speed train were analyzed. Based on curve theory of target distance mode, the piecewise iteration model of braking mode curve for high-speed train was proposed. With MATLAB/Simulink software, the changes of running resistances on flat-straight line, direct ramp with grade 15%o and direct ramp with grade 25‰ for CRH2-300 type high-speed train were analyzed, and the normal braking curves and emergency braking curves of CRH2-300 type and CRH3 type high-speed trains at initial braking speed 300 km ? H-1 were compared. Calculation result indicates that the emergency braking distance of CRH2-300 type high-speed train is 2 786. 68 m on direct ramp, the emergency braking distance of CRH3 type high-speed train is 3 319. 37 m on direct ramp, and both of them are less than 3 700 m, which is the maximum braking distance of braking requirement. Simulation braking curves almost consistent with actual braking curves, which verifies the validity of piecewise iteration algorithm. 1 tab, 12 figs, 10 refs.%研究了时速250 km以上高速列车制动系统,分析了高速列车的运行阻力、制动力与制动距离.根据目标距离模式曲线理论,建立了高速列车的制动模式曲线分段迭代模型.应用MAT-LAB/Simulink软件,分析了CRH2-300型高速列车在平直道上、15‰与25‰直坡道上的运行阻力的变化,对比了CRH2-300型和CRH3型高速列车在制动初速为300 km·h-1时的常用和紧急制动曲线.计算结果表明:在平直道上,CRH2-300型高速列车紧急制动距离为2 786.68 m,CRH3型高速列车紧急制动距离为3 319.37 m,均满足紧急制动距离小于3 700 m的制动要求;仿真制动曲线和实际制动曲线基本一致,验证了分段迭代算法的有效性.

  8. 冷焊工艺参数对HT250表面修复层性能的影响%Effect of Cold-welding Parameters on Properties of HT250 Surface Repaired Layer

    Institute of Scientific and Technical Information of China (English)

    徐庆钟; 李方义; 秦顺顺; 马石磊

    2013-01-01

    冷焊技术是一种新型金属零件表面修复技术,具有精密、经济、便捷等优点,已应用在发动机再制造等领域.利用冷焊技术对发动机缸体材料HT250表面缺陷进行修复,采用金相显微镜、扫描电镜、显微硬度计和拉伸试验机等设备对修复区域的微观组织、硬度和结合强度进行测试分析,同时揭示不同冷焊工艺参数对修复层性能的影响.研究结果表明:基体与修复层结合良好,无孔隙和裂纹,熔合区存在元素扩散,说明修复层与基体间是微区冶金结合;修复层硬度低于基体硬度,便于后续加工处理,热影响区较小;冷焊修复技术能提高修复对象的抗拉强度.同时,热影响区宽度和硬度随冷焊时间和能量工艺参数的增大而增大;抗拉强度的变化随冷焊时间和能量工艺参数的增大先有减小趋势,后逐渐增大.%Cold-welding technology is a new type of metal surface repair technique with advantages of precision, economy and convenience, and has been widely used in engine remanufacturing and other fields. The surface defects of HT250 material used in engine cylinder are repaired by cold-welding technology, then the metallographic microscope, scanning electron microscope, microscopic hardness meter and tensile testing machine are used to analyze microstructure, hardness and bonding strength of repaired region. Meanwhile, the impacts on repaired layer of different process parameters are revealed. Analysis results show that base and repaired layer combine well without pores and cracks, and element diffusion exists in the fusion interface, which illustrates that the relationship between repaired layer and base is metallurgical bonding. The hardness of repaired layer is lower than that of base, which is beneficial to subsequent processing. The width of heat affected zone (HAZ) is relatively narrow. Cold-welding repair technique can improve tensile strength of repaired object. After analyses

  9. Cobalt and molybdenum activated electrodes in foam based alkaline electrolysis cells at 150-250 °C and 40 bar

    DEFF Research Database (Denmark)

    Allebrod, Frank; Chatzichristodoulou, Christodoulos; Mogensen, Mogens Bjerg

    2014-01-01

    , using impedance spectroscopy, cyclic voltammetry and chronoamperometry at an applied cell voltage of 1.5 V, 1.625 V and 1.75 V. The performance of the electrolysis cells was improved by the addition of cobalt oxide and molybdenum oxide as nano sized electro-catalysts. At 250 C current densities of 1...

  10. 50 CFR 660.394 - Latitude/longitude coordinates defining the 180 fm (329 m) through 250 fm (457 m) depth contours.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Latitude/longitude coordinates defining... Latitude/longitude coordinates defining the 180 fm (329 m) through 250 fm (457 m) depth contours. Boundaries for RCAs are defined by straight lines connecting a series of latitude/longitude coordinates....

  11. A pharmacokinetic comparison of cefadroxil and cephalexin after administration of 250, 500 and 1000 mg solution doses.

    Science.gov (United States)

    Barbhaiya, R H

    1996-05-01

    The pharmacokinetics of cefadroxil and cephalexin were examined following single oral doses of either 250, 500 or 1000 mg to a total of 36 healthy volunteers. The volunteers were divided into groups of 12 per dose-group and solution doses of cefadroxil or cephalexin were administered after an overnight fast according to a crossover design for the cephalosporins but not for doses. Serial blood and urine samples were collected from each individual and were analyzed for cefadroxil or cephalexin using validated HPLC assays with UV detection. The individual subject plasma concentration-time data for each cephalosporin were analyzed using noncompartmental methods. Profiles for cephalexin in plasma showed sharper and higher peaks than those for cefadroxil. Although values for the peak concentrations (Cmax) for cefadroxil were lower than that of cephalexin, the levels of cefadroxil in plasma and urine remained above the reported minimum inhibitory concentrations of susceptible organisms for longer period of time than those of cefalexin. The elimination half-life (t1/2) of cefadroxil (about 2 h) was significantly longer than that of cephalexin (about 1 h). The values for Cmax and AUC0-infinity values for both these cephalosporins showed dose-proportional increase, whereas t1/2, renal clearance (CLR) remained independent of dose. These observations confirm that cefadroxil and cephalexin obey linear pharmacokinetics. The CLr of both the cephalosporins were significantly higher than the average glomerular filtration rate at each dose level. The urinary recovery (% Xu) of each cephalosporin, accounted for over 80 per cent of the administered dose, and no significant differences in % Xu were observed between the two cephalosporins. These data suggest that the systemic availability of cefadroxil and cephalexin is similar at each dose level. PMID:8743403

  12. Kinetics and Mechanism of the Gas-Phase Reaction of Selected Carbonyls with Cl Atoms between 250 and 340 K

    Science.gov (United States)

    Hasson, A. S.; Algrim, L.; Abdelhamid, A.; Tyndall, G. S.; Orlando, J. J.

    2013-12-01

    Carbonyls are important products from the gas phase degradation of most volatile organic compounds. Their atmospheric reactions therefore have a significant impact on atmospheric composition, particularly in aged air masses. While the reactions of short-chain linear carbonyls are well understood, the chemistry of larger (> C6) and branched carbonyl is more uncertain. To provide insight into these reactions, the reactions of three carbonyls (methyl isopropyl ketone, MIK; di-isopropyl ketone, DIK; and diethyl ketone, DEK) with chlorine atoms were investigated between 250 and 340 K and 1 atm in the presence and absence of NOx and an HO2 source (methanol). Experiments were performed in a photochemical reactor using a combination of long-path Fourier transform infra-red spectroscopy, proton transfer reaction mass spectrometry and gas chromatography with flame ionization detection. The kinetics were studied using the relative rate technique with butanone and isopropanol as the reference compounds. The Arrhenius expression for the three rate coefficients was determined to be k(DEK+Cl) = 3.87 x 10-11e(2 × 7 kJ/mol)/RT cm3 molecules-1 s-1 , k(MIPK+Cl) = 7.20 x 10-11e(0.2× 8 kJ/mol)/RT cm3 molecules-1 s-1 , and k(DIPK+Cl) = 3.33 x 10-10e(-3× 8 kJ/mol)/RT cm3 molecules-1 s-1 . Measured reaction products accounted for 38-72 % of the reacted carbon and were consistent with strong deactivation of the carbon atom adjacent to the carbonyl group with respect to H-atom abstraction by Cl atoms. The product distributions also provide insight into radical recycling from the organic peroxy + HO2 reaction, and the relative rates of isomerization, fragmentation and reaction with O2 for carbonyl-containing alkoxy radicals. Implications of these results will be discussed.

  13. Geologic map of the east half of the Lime Hills 1:250,000-scale quadrangle, Alaska

    Science.gov (United States)

    Gamble, Bruce M.; Reed, Bruce L.; Richter, Donald H.; Lanphere, Marvin A.

    2013-01-01

    This map is compiled from geologic mapping conducted between 1985 and 1992 by the U.S. Geological Survey as part of the Alaska Mineral Resource Assessment Program. That mapping built upon previous USGS work (1963–1988) unraveling the magmatic history of the Alaska–Aleutian Range batholith. Quaternary unit contacts depicted on this map are derived largely from aerial-photograph interpretation. K-Ar ages made prior to this study have been recalculated using 1977 decay constants. The east half of the Lime Hills 1:250,000-scale quadrangle includes part of the Alaska–Aleutian Range batholith and several sequences of sedimentary rocks or mixed sedimentary and volcanic rocks. The Alaska–Aleutian Range batholith contains rocks that represent three major igneous episodes, (1) Early and Middle Jurassic, (2) Late Cretaceous and early Tertiary, and (3) middle Tertiary; only rocks from the latter two episodes are found in this map area. The map area is one of very steep and rugged terrain; elevations range from a little under 1,000 ft (305 m) to 9,828 ft (2,996 m). Foot traverses are generally restricted to lowermost elevations. Areas suitable for helicopter landings can be scarce at higher elevations. Most of the area was mapped from the air, supplemented by direct examination of rocks where possible. This restricted access greatly complicates understanding some of the more complex geologic units. For example, we know there are plutons whose compositions vary from gabbro to granodiorite, but we have little insight as to how these phases are distributed and what their relations might be to each other. It is also possible that some of what we have described as compositionally complex plutons might actually be several distinct intrusions.

  14. Crown plasticity and competition for canopy space: a new spatially implicit model parameterized for 250 North American tree species.

    Directory of Open Access Journals (Sweden)

    Drew W Purves

    Full Text Available BACKGROUND: Canopy structure, which can be defined as the sum of the sizes, shapes and relative placements of the tree crowns in a forest stand, is central to all aspects of forest ecology. But there is no accepted method for deriving canopy structure from the sizes, species and biomechanical properties of the individual trees in a stand. Any such method must capture the fact that trees are highly plastic in their growth, forming tessellating crown shapes that fill all or most of the canopy space. METHODOLOGY/PRINCIPAL FINDINGS: We introduce a new, simple and rapidly-implemented model--the Ideal Tree Distribution, ITD--with tree form (height allometry and crown shape, growth plasticity, and space-filling, at its core. The ITD predicts the canopy status (in or out of canopy, crown depth, and total and exposed crown area of the trees in a stand, given their species, sizes and potential crown shapes. We use maximum likelihood methods, in conjunction with data from over 100,000 trees taken from forests across the coterminous US, to estimate ITD model parameters for 250 North American tree species. With only two free parameters per species--one aggregate parameter to describe crown shape, and one parameter to set the so-called depth bias--the model captures between-species patterns in average canopy status, crown radius, and crown depth, and within-species means of these metrics vs stem diameter. The model also predicts much of the variation in these metrics for a tree of a given species and size, resulting solely from deterministic responses to variation in stand structure. CONCLUSIONS/SIGNIFICANCE: This new model, with parameters for US tree species, opens up new possibilities for understanding and modeling forest dynamics at local and regional scales, and may provide a new way to interpret remote sensing data of forest canopies, including LIDAR and aerial photography.

  15. Study on Potato and Tomato Late Blights Controlled by 250 g/L Azoxystrobin SC in Wuling Mountain%250g/L嘧菌酯悬浮剂防治武陵山区马铃薯及番茄晚疫病的试验研究

    Institute of Scientific and Technical Information of China (English)

    向前; 刘传清; 张锋涛

    2011-01-01

    进行250 g/L嘧菌酯悬浮剂防治武陵山区马铃薯及番茄晚疫病的试验研究,结果表明:250 g/L嘧菌酯悬浮剂茎叶处理对马铃薯及番茄晚疫病均有一定的防效,速效性及持效性均显著或极显著优于对照药剂,并对作物安全,防病增产效果突出。%This paper disscussed potato and tomato late blights controlled by 250 g/L azoxystrobin SC in Wuling Mountain.The results showed that leaf dealing by 250 g/L azoxystrobin SC could control potato and tomato late blights in a certain extent,whose readily availability and continuity were significantly or remarkbly significantly superior than those of CK.250 g/L axoxystrobin SC was safe to crops,the effects of disease control and yield increasing were significant.

  16. 一种致遗传性凝血因子Ⅶ缺陷症的新突变(Ser250Phe)的鉴定与功能分析%Identification and functional analysis of a novel missense mutation Ser250Phe underlying congenital coagulation factor Ⅶ deficiency

    Institute of Scientific and Technical Information of China (English)

    江明华; 王兆钺; 余自强; 苏健; 曹丽娟; 张威

    2013-01-01

    目的 探讨Ser250Phe突变致遗传性凝血因子Ⅶ(coagulation factorⅦ,FⅦ)缺陷的分子机制.方法 用STA-R全自动血凝分析仪检测先证者及家系成员的凝血酶原时间(prothrombin time,PT)、活化部分凝血活酶时间(activated partial thrombinoplastin time,APTT)、纤维蛋白原(fibrinogen,FIB)及凝血酶时间(thrombin time,TT);一步法及ELISA分别检测先证者及家系成员凝血因子Ⅶ活性及抗原;PCR扩增先证者及其家系成员因子7基因(factor 7 gene,F7)所有外显子及侧翼序列,直接测序分析;PCR介导质粒DNA定点诱变法构建F7 Ser250Phe突变表达质粒,将表达质粒瞬时转染HEK293细胞,一步法测定培养上清FⅦ活性及ELISA及Western印迹测定培养上清及细胞裂解液FⅦ抗原;同时将F7表达质粒与高尔基体或内质网定位的荧光质粒共转染CHO细胞进行亚细胞定位分析.结果 先证者及家系成员APTT、TT及FIB均正常,而先证者PT、FⅦ活性及抗原分别为36.5 s、4.0%及130.2 ng/mL;测序发现先证者F7基因存在g.15975G>A(IVS6-1 G>A)与g.16750 C> T(Ser250Phe)双杂合突变,其父亲为g.16750 C>T杂合子,母亲为g.15975G>A杂合子,妹妹不携带这两种突变;HEK293细胞上清中FⅦ250Phe活性为(4.12±0.61)%(以FⅦ250Ser载体转染细胞培养上清FⅦ活性作为100%),培养上清中FⅦ250Ser与FⅦ250Phe抗原水平分别为(37.77±2.30)ng/mL和(4.02±0.52) ng/mL;而细胞裂解液中FⅦ250Ser与FⅦ250Phe抗原水平分别为(172.45±2.25) ng/mL和(130.51±2.32) ng/mL;Western印迹分析示转染了FⅦ250Phe载体的HEK293细胞培养上清无可检测FⅦ抗原,而在细胞裂解液中检测到FⅦ抗原,与ELISA检测结果一致;在CHO细胞表达的重组FⅦ250Phe绿色荧光信号能与核周内质网红色荧光信号重合,而且也与高尔基体红色信号重合,与重组FⅦ250Ser一致.结论 复合IVS6-1G>A与Ser250Phe突变是导致患者遗传性凝血因

  17. Mapping Irrigated Areas of Ghana Using Fusion of 30 m and 250 m Resolution Remote-Sensing Data

    Directory of Open Access Journals (Sweden)

    Arnel Rala

    2011-04-01

    Full Text Available Maps of irrigated areas are essential for Ghana’s agricultural development. The goal of this research was to map irrigated agricultural areas and explain methods and protocols using remote sensing. Landsat Enhanced Thematic Mapper (ETM+ data and time-series Moderate Resolution Imaging Spectroradiometer (MODIS data were used to map irrigated agricultural areas as well as other land use/land cover (LULC classes, for Ghana. Temporal variations in the normalized difference vegetation index (NDVI pattern obtained in the LULC class were used to identify irrigated and non-irrigated areas. First, the temporal variations in NDVI pattern were found to be more consistent in long-duration irrigated crops than with short-duration rainfed crops due to more assured water supply for irrigated areas. Second, surface water availability for irrigated areas is dependent on shallow dug-wells (on river banks and dug-outs (in river bottoms that affect the timing of crop sowing and growth stages, which was in turn reflected in the seasonal NDVI pattern. A decision tree approach using Landsat 30 m one time data fusion with MODIS 250 m time-series data was adopted to classify, group, and label classes. Finally, classes were tested and verified using ground truth data and national statistics. Fuzzy classification accuracy assessment for the irrigated classes varied between 67 and 93%. An irrigated area derived from remote sensing (32,421 ha was 20–57% higher than irrigated areas reported by Ghana’s Irrigation Development Authority (GIDA. This was because of the uncertainties involved in factors such as: (a absence of shallow irrigated area statistics in GIDA statistics, (b non-clarity in the irrigated areas in its use, under-development, and potential for development in GIDA statistics, (c errors of omissions and commissions in the remote sensing approach, and (d comparison involving widely varying data types, methods, and approaches used in determining irrigated

  18. Susceptibility of Granite Rock to scCO2/Water at 200 degrees C and 250 degrees C

    Energy Technology Data Exchange (ETDEWEB)

    Sugama, T.; Gill, S., Ecker, L., Butcher, T., Warren, J.

    2011-01-01

    Granite rock comprising anorthoclase-type albite and quartz as its major phases and biotite mica as the minor one was exposed to supercritical carbon dioxide (scCO{sub 2})/water at 250 C and 13.78 MPa pressure for 104 hours. For comparison purpose, four other rocks, albite, hornblende, diorite, and quartz, also were exposed. During the exposure of granite, ionic carbonic acid, known as the wet carbonation reactant, preferentially reacted with anorthoclase-type albite and biotite, rather than with quartz. The susceptibility of biotite to wet carbonation was higher than that of anorthoclase-type albite. All the carbonation by-products of anorthoclase-type albite were amorphous phases including Na- and K-carbonates, a kaolinite clay-like compound, and silicon dioxide, while wet carbonation converted biotite into potassium aluminum silicate, siderite, and magnesite in crystalline phases and hydrogen fluoride (HF). Three of these reaction by-products, Na- and K-carbonates and HF, were highly soluble in water. Correspondingly, the carbonated top surface layer, about 1.27 mm thick as carbonation depth, developed porous microstructure with numerous large voids, some of which have a size of {>=} 10 {mu}m, reflecting the erosion of granite by the leaching of these water-soluble reaction by-products. Comparing with this carbonation depth, its depth of other minerals was considerable lower, particularly, for hornblende and diorite with 0.07 and 0.02 mm, while no carbonate compound was detected in quartz. The major factor governing these low carbonation depths in these rocks was the formation of water-insensitive scale-like carbonate by-products such as calcite (CaCO{sub 3}), siderite (FeCO{sub 3}), and magnesite (MgCO{sub 3}). Their formation within the superficial layer of these minerals served as protective barrier layer that inhibits and retards further carbonation of fresh underlying minerals, even if the exposure time was extended. Thus, the coverage by this barrier layer

  19. Wide Area Wetland Mapping in Semi-Arid Africa Using 250-Meter MODIS Metrics and Topographic Variables

    Directory of Open Access Journals (Sweden)

    Andreas Dietz

    2010-07-01

    Full Text Available Wetlands in West Africa are among the most vulnerable ecosystems to climate change. West African wetlands are often freshwater transfer mechanisms from wetter climate regions to dryer areas, providing an array of ecosystem services and functions. Often wetland-specific data in Africa is only available on a per country basis or as point data. Since wetlands are challenging to map, their accuracies are not well considered in global land cover products. In this paper we describe a methodology to map wetlands using well-corrected 250-meter MODIS time-series data for the year 2002 and over a 360,000 km2 large study area in western Burkina Faso and southern Mali (West Africa. A MODIS-based spectral index table is used to map basic wetland morphology classes. The index uses the wet season near infrared (NIR metrics as a surrogate for flooding, as a function of the dry season chlorophyll activity metrics (as NDVI. Topographic features such as sinks and streamline areas were used to mask areas where wetlands can potentially occur, and minimize spectral confusion. 30-m Landsat trajectories from the same year, over two reference sites, were used for accuracy assessment, which considered the area-proportion of each class mapped in Landsat for every MODIS cell. We were able to map a total of five wetland categories. Aerial extend of all mapped wetlands (class “Wetland” is 9,350 km2, corresponding to 4.3% of the total study area size. The classes “No wetland”/“Wetland” could be separated with very high certainty; the overall agreement (KHAT was 84.2% (0.67 and 97.9% (0.59 for the two reference sites, respectively. The methodology described herein can be employed to render wide area base line information on wetland distributions in semi-arid West Africa, as a data-scarce region. The results can provide (spatially interoperable information feeds for inter-zonal as well as local scale water assessments.

  20. Sources of high frequency seismic noise: insights from a dense network of ~250 stations in northern Alsace (France)

    Science.gov (United States)

    Vergne, Jerome; Blachet, Antoine; Lehujeur, Maximilien

    2015-04-01

    Monitoring local or regional seismic activity requires stations having a low level of background seismic noise at frequencies higher than few tenths of Hertz. Network operators are well aware that the seismic quality of a site depends on several aspects, among them its geological setting and the proximity of roads, railways, industries or trees. Often, the impact of each noise source is only qualitatively known which precludes estimating the quality of potential future sites before they are tested or installed. Here, we want to take advantage of a very dense temporary network deployed in Northern Alsace (France) to assess the effect of various kinds of potential sources on the level of seismic noise observed in the frequency range 0.2-50 Hz. In September 2014, more than 250 seismic stations (FairfieldNodal@ Zland nodes with 10Hz vertical geophone) have been installed every 1.5 km over a ~25km diameter disc centred on the deep geothermal sites of Soultz-sous-Forêts and Rittershoffen. This region exhibits variable degrees of human imprints from quite remote areas to sectors with high traffic roads and big villages. It also encompasses both the deep sedimentary basin of the Rhine graben and the piedmont of the Vosges massif with exposed bedrock. For each site we processed the continuous data to estimate probability density functions of the power spectral densities. At frequencies higher than 1 Hz most sites show a clear temporal modulation of seismic noise related to human activity with the well-known variations between day and night and between weekdays and weekends. Moreover we observe a clear evolution of the spatial distribution of seismic noise levels with frequency. Basically, between 0.5 and 4 Hz the geological setting modulates the level of seismic noise. At higher frequencies, the amplitude of seismic noise appears mostly related to the distance to nearby roads. Based on road maps and traffic estimation, a forward approach is performed to model the induced

  1. Accuracy of genomic predictions of residual feed intake and 250-day body weight in growing heifers using 625,000 single nucleotide polymorphism markers.

    Science.gov (United States)

    Pryce, J E; Arias, J; Bowman, P J; Davis, S R; Macdonald, K A; Waghorn, G C; Wales, W J; Williams, Y J; Spelman, R J; Hayes, B J

    2012-04-01

    Feed makes up a large proportion of variable costs in dairying. For this reason, selection for traits associated with feed conversion efficiency should lead to greater profitability of dairying. Residual feed intake (RFI) is the difference between actual and predicted feed intakes and is a useful selection criterion for greater feed efficiency. However, measuring individual feed intakes on a large scale is prohibitively expensive. A panel of DNA markers explaining genetic variation in this trait would enable cost-effective genomic selection for this trait. With the aim of enabling genomic selection for RFI, we used data from almost 2,000 heifers measured for growth rate and feed intake in Australia (AU) and New Zealand (NZ) genotyped for 625,000 single nucleotide polymorphism (SNP) markers. Substantial variation in RFI and 250-d body weight (BW250) was demonstrated. Heritabilities of RFI and BW250 estimated using genomic relationships among the heifers were 0.22 and 0.28 in AU heifers and 0.38 and 0.44 in NZ heifers, respectively. Genomic breeding values for RFI and BW250 were derived using genomic BLUP and 2 bayesian methods (BayesA, BayesMulti). The accuracies of genomic breeding values for RFI were evaluated using cross-validation. When 624,930 SNP were used to derive the prediction equation, the accuracies averaged 0.37 and 0.31 for RFI in AU and NZ validation data sets, respectively, and 0.40 and 0.25 for BW250 in AU and NZ, respectively. The greatest advantage of using the full 624,930 SNP over a reduced panel of 36,673 SNP (the widely used BovineSNP50 array) was when the reference population included only animals from either the AU or the NZ experiment. Finally, the bayesian methods were also used for quantitative trait loci detection. On chromosome 14 at around 25 Mb, several SNP closest to PLAG1 (a gene believed to affect stature in humans and cattle) had an effect on BW250 in both AU and NZ populations. In addition, 8 SNP with large effects on RFI were

  2. Crystal structures of iron bearing tetrahedrite and tennantite at 25 and 250 degrees C by means of Rietveld refinement of synchrotron data

    DEFF Research Database (Denmark)

    Friese, Karen; Grzechnik, Andrzej; Makovicky, Emil;

    2008-01-01

    Rietveld refinement of X-ray synchrotron data was performed for two synthetic tetrahedrite samples, with 0.61 and 1.83 Fe atoms, and two synthetic tennantite samples with 0.10 and 1.23 Fe atoms p.f.u. M-12(Sb,As)(4)S-13. Measurements were performed at 25 and 250 degrees C. For both the phases, in...

  3. Role of combined hystero-laparoscopy in the evaluation of female infertility as one step procedure: a retrospective analytical study of 250 patients

    OpenAIRE

    Ramesh, B; Shraddha Neminath Kurkuri

    2016-01-01

    Background: Infertility is defined as a failure of a couple to conceive after having regular, unprotected sexual intercourse for one year. To determine the role of combined hystero-laparoscopy in the evaluation of female infertility patients with no significant clinical/ ultrasonography findings and to calculate the incidence of various pathological conditions in the female reproductive tract leading to infertility. Methods: This retrospective analytical study was done in 250 patients with...

  4. Genomewide Linkage Analyses of Bipolar Disorder: A New Sample of 250 Pedigrees from the National Institute of Mental Health Genetics Initiative

    OpenAIRE

    Dick, Danielle M; Foroud, Tatiana; Flury, Leah; Bowman, Elizabeth S.; Miller, Marvin J.; Rau, N. Leela; Moe, P. Ryan; Samavedy, Nalini; El-Mallakh, Rif; Manji, Husseini; Glitz, Debra A.; Meyer, Eric T.; Smiley, Carrie; Hahn, Rhoda; Widmark, Clifford

    2003-01-01

    We conducted genomewide linkage analyses on 1,152 individuals from 250 families segregating for bipolar disorder and related affective illnesses. These pedigrees were ascertained at 10 sites in the United States, through a proband with bipolar I affective disorder and a sibling with bipolar I or schizoaffective disorder, bipolar type. Uniform methods of ascertainment and assessment were used at all sites. A 9-cM screen was performed by use of 391 markers, with an average heterozygosity of 0.7...

  5. The geomagnetic dipole moment variation between 250 and 800 ka BP reconstructed from the authigenic 10Be/9Be signature in West Equatorial Pacific sediments

    Science.gov (United States)

    Ménabréaz, Lucie; Thouveny, Nicolas; Bourlès, Didier L.; Vidal, Laurence

    2014-01-01

    The authigenic 10Be/9Be ratio, proxy of the cosmogenic radionuclide 10Be production rate in the atmosphere, was measured in sediments deposited in the West Equatorial Pacific (Gulf of Papua; 10°25 S; 146°15 E), in order to reconstruct the geomagnetic dipole moment variations in the 250-800 ka time interval, independently from paleomagnetic methods. The pelagic clayey-carbonate muds continuously deposited between marine isotope stages 8 and 20 were subsampled every 10 cm. The 10Be production rate record reconstructed for the 250-800 ka interval is described and compared over the same time interval with global paleomagnetic stacks (SINT-2000 and PISO-1500). The highlighted cosmogenic 10Be overproductions appear to be triggered by the series of Geomagnetic Dipole Lows (GDL) that have occurred since the Brunhes-Matuyama reversal. Calibration using absolute values of the geomagnetic dipole moment drawn from a paleomagnetic database produces a new record of the dipole moment variations over the 250-800 ka time interval. The timing and amplitude of the GDL succession revealed by such records will contribute to improving knowledge of the geodynamo rhythms and rate of changes at millennial to million year scales.

  6. Fabrication of mAb G250-SPIO molecular magnetic resonance imaging nanoprobe for the specific detection of renal cell carcinoma in vitro.

    Directory of Open Access Journals (Sweden)

    Cailuan Lu

    Full Text Available Molecular magnetic resonance imaging (mMRI has been paid more and more attention for early diagnosis of cancer. A sensitive and specific mMRI probe plays the most important role in this technique. In this study, superparamagnetic iron oxide (SPIO nanoparticles and mAb G250 were conjugated as mMRI probe for the detection of clear cell renal cell carcinoma (ccRCC using 3.0-Tesla MRI in vitro. mAb G250 could specifically recognize carbonic anhydrase IX (CAIX antigen overexpressed in ccRCC and the SPIO nanoparticles as MRI contrast agent presented excellent MRI response and good biocompatibility. The successful assembly of this nanoprobe was confirmed by UV-vis spectrum, FT-IR spectroscopy and DLS analysis. In vitro MRI study on ccRCC cells and control cells indicated that our fabricated mAb G250-SPIO nanoprobe could be used in the specific labeling of clear cell renal carcinoma cells successfully.

  7. Neutron- and proton-induced nuclear data evaluation of thorium, uranium and curium isotopes for energies up to 250 MeV

    CERN Document Server

    Young, Ouk Lee; Jonghwa, Chang; Konobeyev, A Yu

    2004-01-01

    The evaluation of neutron- and proton nuclear data for thorium-232, U-233,234,236, and Cm-243,244,245,246 isotopes have been performed at energies up to 250 MeV. Neutron data was evaluated at energies from 20 MeV to 250 MeV, and combined with the JENDL-3.3 data at 20 MeV while proton data was obtained for energies from 1 to 250 MeV. Nuclear model parameters are largely based on the IAEA-RIPL recommendation, and adjusted to better reproduce the available measurements. The coupled channel optical model was applied to calculate the total, reaction, elastic, and direct inelastic cross sections, and to obtain the transmission coefficients. Decay of excited nuclei was described with the Hauser-Feshbach and exciton models using the GNASH code to simultaneously handle neutron, proton, deuteron, triton, helium-3, alpha , gamma emissions and fissions. Special attention was paid on the fission cross sections for energies where experimental data are scant, using appropriate systematics and fittings. Particles and gamma e...

  8. An evaluation of time-series MODIS 250-meter vegetation index data for crop mapping in the United States Central Great Plains

    Science.gov (United States)

    Wardlow, Brian Douglas

    The objectives of this research were to: (1) investigate time-series MODIS (Moderate Resolution Imaging Spectroradiometer) 250-meter EVI (Enhanced Vegetation Index) and NDVI (Normalized Difference Vegetation Index) data for regional-scale crop-related land use/land cover characterization in the U.S. Central Great Plains and (2) develop and test a MODIS-based crop mapping protocol. A pixel-level analysis of the time-series MODIS 250-m VIs for 2,000+ field sites across Kansas found that unique spectral-temporal signatures were detected for the region's major crop types, consistent with the crops' phenology. Intra-class variations were detected in VI data associated with different land use practices, climatic conditions, and planting dates for the crops. The VIs depicted similar seasonal variations and were highly correlated. A pilot study in southwest Kansas found that accurate and detailed cropping patterns could be mapped using the MODIS 250-m VI data. Overall and class-specific accuracies were generally greater than 90% for mapping crop/non-crop, general crops (alfalfa, summer crops, winter wheat, and fallow), summer crops (corn, sorghum, and soybeans), and irrigated/non-irrigated crops using either VI dataset. The classified crop areas also had a high level of agreement (90%) between their classified crop patterns. This hierarchical crop mapping protocol was tested for Kansas and produced similar classification results over a larger and more diverse area. Overall and class-specific accuracies were typically between 85% and 95% for the crop maps. At the state level, the maps had a high level of areal agreement (<5% difference) with the USDA crop area figures and their classified patterns were consistent with the state's cropping practices. In general, the protocol's performance was relatively consistent across the state's range of environmental conditions, landscape patterns, and cropping practices. The largest areal differences occurred in eastern Kansas due to

  9. Premature Infants 750–1,250 g Birth Weight Supplemented with a Novel Human Milk-Derived Cream Are Discharged Sooner

    OpenAIRE

    Amy B. Hair; Bergner, Erynn M.; Lee, Martin L; MOREIRA, Alvaro G.; Hawthorne, Keli M.; Rechtman, David J; Abrams, Steven A.; Blanco, Cynthia L.

    2016-01-01

    Abstract Objective: Infants may benefit from early nutritional intervention to decrease hospital stay. To evaluate the effects of adding a human milk (HM)-derived cream (Cream) product to a standard feeding regimen in preterm infants. Materials and Methods: In a prospective multicenter randomized study, infants with birth weights 750–1,250 g were assigned to a Control or Cream group. The Control group received a standard feeding regimen consisting of mother's own milk or donor HM with donor H...

  10. Cluster formation during expansion of hot and compressed nuclear matter produced in central collisions of Au on Au at 250{ital A} MeV

    Energy Technology Data Exchange (ETDEWEB)

    Petrovici, M.; Herrmann, N.; Legrand, I.; Gobbi, A.; Hildenbrand, K.D.; Reisdorf, W.; Buta, A.; Freifelder, R.; Jeong, S.C.; Kraemer, M.; Moisa, D.; Schuell, D.; Simion, V.; Sodan, U.; Teh, K.; Wessels, J.P.; Wienold, T.; Alard, J.P.; Amouroux, V.; Basrak, Z.; Bastid, N.; Belyaev, I.M.; Berger, L.; Blaich, T.; Boussange, S.; Caplar, R.; Cerruti, C.; Cindro, N.; Coffin, J.P.; Dona, R.; Dupieux, P.; Eroe, J.; Fintz, P.; Fodor, Z.; Fraysse, L.; Guillaume, G.; Hoelbling, S.; Houari, A.; Jundt, F.; Kecskemeti, J.; Koncz, P.; Korchagin, Y.; Kotte, R.; Kuhn, C.; Ibnouzahir, M.; Lebedev, A.; Maguire, C.; Manko, V.; Moesner, J.; Montarou, G.; Montbel, I.; Morel, P.; Neubert, W.; Pelte, D.; Rami, F.; Ramillien, V.; Sadchikov, A.; Seres, Z.; Sikora, B.; Smolyankin, S.; Tezkratt, R.; Trzaska, M.; Vasiliev, M.A.; Wagner, P.; Wilhelmi, Z.; Wohlfarth, D.; Zhilin, A.V. [Gesellschaft fuer Schwerionenforschung, Darmstadt (Germany)]|[Institute for Physics and Nuclear Engineering, Bucharest (Romania)]|[Central Research Institute for Physics, Budapest (Hungary)]|[Laboratoire de Physique Corpusculaire/IN2P3-CNRS/Universite Blaise Pascal, Clermont-Ferrand (France)]|[Physikalisches Institut der Universitaet Heidelberg, Heidelberg (Germany)]|[Universitaet Mainz, Mainz (Germany)]|[Institute for Theoretical and Experimental Physics, Moscow (Russian Federation)]|[Kurchatov Institute for Atomic Energy, Moscow (Russian Federation)]|[Forschungszentrum Rossendorf, Rossendorf (Germany)]|[Centre de Recherches Nucleaires/Universite Louis Pasteur, Strasbourg (France)]|[Institute of Experimental Physics, University of Warsaw, Warsaw (Poland)]|[Rudjer Boskovic Institute, Zagreb (Croatia)]|[Laboratori Nationali di Legnaro, Legnaro (Italy); (FOPI Collaboration)

    1995-06-19

    Complete distributions of the light and intermediate mass fragments ({ital Z}=1--6) produced within the polar angular range 1{sup {circ}}{le}{Theta}{sub lab}{le}30{sup {circ}} in highly central collisions of 250{ital A} MeV Au+Au are presented. The results of this measurement and a model analysis are used to study the expansion and clustering of the hot and compressed transient state formed in central collisions of such a heavy system. The influence of the initial conditions on the final observables is discussed.

  11. Characterization of 720 and 940 MHz Oscillators with Chip Antenna for Wireless Sensors from Room Temperature to 200 and 250 deg C

    Science.gov (United States)

    Scardelletti, Maximilian C.; Ponchak, George E.

    2011-01-01

    Oscillators that operate at 720 and 940 MHz and characterized over a temperature range of 25 C to 200 C and 250 C, respectively, are presented. The oscillators are designed on alumina substrates with typical integrated circuit fabrication techniques. Cree SiC MESFETs, thin film metal-insulator-metal capacitors and spiral inductors, and Johanson miniature chip antennas make-up the circuits. The output power and phase noise are presented as a function of temperature and frequency. Index Terms MESFETS, chip antennas, oscillators SiC alumina.

  12. L'actionnariat salarié dans les entreprises familiales du SBF250:un outil de création de valeur ?

    OpenAIRE

    Stéphane Trébucq

    2002-01-01

    The present study investigates the impact on wealth creation for shareholders when businesses are both family-owned and have ESOPs. Using data for 109 large quoted French firms from the SBF250 index, the study tends to confirm that family-controlled firms create more shareholder value but open their capital to non-management employees less often than non-family businesses do. The supposed positive impact of non-managing employee ownership on wealth creation is not confirmed. It is interesting...

  13. Transmission measurement of photo-absorption cross section of aluminum in soft X-ray region of 50 to 250 eV

    Institute of Scientific and Technical Information of China (English)

    CHEN Kai; CUI Ming-Qi; ZHENG Lei

    2008-01-01

    The photo-absorption cross section of aluminum was obtained from the ratio of transmission of aluminum thin-films with different area densities from 50 to 250 eV with synchrotron radiation monochromatic beam.Two samples with different area densities were used to minimize the uncertainty caused by the sample surface oxidation and systematic factors of the X-ray source,beamline,and detector.The experimental results are in good agreement with the published data and FEFF program calculations in general.

  14. pi. sup 0 and. eta. meson production in. pi. sup + p and K sup + p collisions at 250 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Atayan, M.R.; Gevorkyan, G.V. (Institute of Physics, Erevan (Armenia)); Botterweck, F.; Charlet, M.; Kittel, W. (Nijmegen Univ. (Netherlands) NIKHEF-H, Nijmegen (Netherlands)); Chliapnikov, P.V.; Ronjin, V.M.; Tchikilev, O.G. (Institute of High Energy Physics, Protvino (Russia)); Roeck, A. de; Wolf, E.A. de; Verbeure, F. (Inter-University Inst. for High Energies, Brussels (Belgium) Universitaire Instelling Antwerp, Wilrijk (Belgium). Dept. of Physics); Dziunikowska, K.; Kisielewska, D.; Olkiewicz, K. (Academy of Mining and Metallurgy, Krakow (Poland). Inst. of Physics and Nuclear Technique Institute of Nuclear Physics, Krakow (Poland)); Endler, A.M. (Centro Brasileiro de Pesquisas Fisicas, Rio de Janeiro, RJ (Brazil)); Fisyak, Yu.V.; Shabalina, E.K.; Sotnikova, N.A.; Tikhonova, L.A.; Zotkin, S.A. (Moscow State Univ. (Russia). Nuclear Physics Inst.); Wischnewski, R. (Institut fuer Hochenergiephysik, Zeuthen (Germany)); EHS/NA22 Collaboration

    1992-05-01

    We report on a study of inclusive {pi}{sup 0} and {eta} meson production in {pi}{sup +}p and K{sup +}p interactions at 250 GeV/c beam momentum. The Feynman-x spectrum of {pi}{sup 0} is very similar in shape and normalization to that of negatively charged particles produced in the same experiment. The results are compared with data at other energies and with FRITIOF model predictions. This model overestimates the {eta} cross section by a factor of 2.5. It reproduces the {pi}{sup 0} cross section correctly, but predicts a too hard {pi}{sup 0}x distribution. (orig.).

  15. Digital mapping of soil properties in Canadian managed forests at 250 m of resolution using the k-nearest neighbor method

    Science.gov (United States)

    Mansuy, N. R.; Paré, D.; Thiffault, E.

    2015-12-01

    Large-scale mapping of soil properties is increasingly important for environmental resource management. Whileforested areas play critical environmental roles at local and global scales, forest soil maps are typically at lowresolution.The objective of this study was to generate continuous national maps of selected soil variables (C, N andsoil texture) for the Canadian managed forest landbase at 250 m resolution. We produced these maps using thekNN method with a training dataset of 538 ground-plots fromthe National Forest Inventory (NFI) across Canada,and 18 environmental predictor variables. The best predictor variables were selected (7 topographic and 5 climaticvariables) using the Least Absolute Shrinkage and Selection Operator method. On average, for all soil variables,topographic predictors explained 37% of the total variance versus 64% for the climatic predictors. Therelative root mean square error (RMSE%) calculated with the leave-one-out cross-validation method gave valuesranging between 22% and 99%, depending on the soil variables tested. RMSE values b 40% can be considered agood imputation in light of the low density of points used in this study. The study demonstrates strong capabilitiesfor mapping forest soil properties at 250m resolution, compared with the current Soil Landscape of CanadaSystem, which is largely oriented towards the agricultural landbase. The methodology used here can potentiallycontribute to the national and international need for spatially explicit soil information in resource managementscience.

  16. Buckling measurements up to 250 deg C on lattices of Agesta clusters and on D{sub 2}O alone in the pressurized exponential assembly TZ

    Energy Technology Data Exchange (ETDEWEB)

    Persson, R.; Andersson, A.J.W.; Wikdahl, C.E.

    1966-11-15

    Buckling determinations by means of flux mapping were performed in TZ up to 250 deg C on two lattices of Aagesta fuel assemblies in D{sub 2}O and on D{sub 2}O alone. Most of the flux measurements were made with fission counters in pressure thimbles. The perturbations caused by the thimbles were studied experimentally in various ways and compared with two group diffusion-theory calculations. In one of the lattices the effectiveness of a control rod (AglnCd) was also investigated. The results of the diffusion length experiments indicated some systematic error of the order of 0.15 - 0.10/m{sup 2} in the bucklings measured, though the temperature dependence should be well established. The bucklings of the two lattices studied (square pitches 24 and 27 cm) were found to be less sensitive to temperature than theoretical calculations predict, the temperature coefficient being more than 10 per cent smaller. The buckling changes from 20 to 250 deg C were about -2.4 and -1.8/m{sup 2}, respectively, for the two lattices. During part of the experimental period we had, for some unexplained reason, about 30 per cent excess absorption in the heavy water.

  17. Recent results on the neutron irradiation of ITER candidate copper alloys irradiated in DR-3 at 250{degrees}C to 0.3 dpa

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, D.J. [Pacific Northwest National Lab., Richland, WA (United States); Singh, B.N.; Toft, P.; Eldrup, M.

    1997-04-01

    Tensile specimens of CuCrZr and CuNiBe alloys were given various heat treatments corresponding to solution anneal, prime-ageing and bonding thermal treatment with additional specimens re-aged and given a reactor bakeout treatment at 350{degrees}C for 100 h. CuAl-25 was also heat treated to simulate the effects of a bonding thermal cycle on the material. A number of heat treated specimens were neutron irradiated at 250{degrees}C to a dose level of {approximately}0.3 dpa in the DR-3 reactor as Riso. The main effect of the bonding thermal cycle heat treatment was a slight decrease in strength of CuCrZr and CuNiBe alloys. The strength of CuAl-25, on the other hand, remained almost unaltered. The post irradiation tests at 250{degrees}C showed a severe loss of ductility in the case of the CuNiBe alloy. The irradiated CuAl-25 and CuCrZr specimens exhibited a reasonable amount of uniform elongation, with CuCrZr possessing a lower strength.

  18. Thread core processed in DMG GMX 250 linear%螺纹型心在车铣复合中心的加工

    Institute of Scientific and Technical Information of China (English)

    程园虎; 赖天琴

    2011-01-01

    The function of DMG GMX 250 linear mill-turn center is introduced briefly in this paper. By analyzing the thread core in cap mold, the method of the common cutters' deflection is proposed, a new machining plan and process of this part based on the mill-turn center are presented and the problem occurred in the process is solved. As a result, the machining accuracy is improved and the cost is reduced. This method has been put into use extensively and produces a great economic benefit.%介绍了DMG GMX 250车铣复合中心的机床特点.通过对防盗盖螺纹型芯零件特点的分析,提出了常规刀具角度偏摆的加工方法,建立了基于车铣复合中心加工的新型方案及工艺流程,解决了生产过程中出现的问题.该方案提高了产品的加工精度,降低了加工成本,经批量使用,产生了良好的经济效益.

  19. Low cycle fatigue behaviour of neutron irradiated copper alloys at 250 and 350 deg. C. (ITER R and D Task no. T213)[International Thermonuclear Experimental Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Singh, B.N.; Stubbins, J.F. [Illinois Univ., Dept. of Nuclear Engineering, Illinois (United States); Toft, P

    2000-03-15

    The fatigue behaviour of a dispersion strengthened and a precipitation hardened copper alloys was investigated with and without irradiation exposure. Fatigue specimens of these alloys were irradiated with fission neutrons in the DR-3 reactor at Risoe with a flux of {approx}2.5 x 10{sup 17} n/m{sup 2}s (E> 1 MeV) to influence levels of 1.0 - 1.5 x 10{sup 24} n/m{sup 2} (E> 1 MeV) at 250 and 350 deg. C. These irradiations were carried out in temperature controlled rigs where the irradiation temperature was monitored and controlled continuously throughout the whole irradiation experiment. Both unirradiated and irradiated specimens were fatigue tested in vacuum at the irradiation temperatures of 250 and 350 deg. C in a strain controlled mode with a loading frequency of 0.5Hz. Post-fatigue microstructures were examined using transmission electron microscopy and the fracture surfaces were investigated using scanning electron microscope. The present investigations demonstrated that the fatigue life decreases with increasing temperature and that the exposure to neutron irradiation causes further degradation in fatigue life at both temperatures. These results are discussed in terms of the observed post-fatigue microstructures and the fracture surface morphology. Finally, the main conclusions and their implications are summarised. (au)

  20. Granulocyte-specific monoclonal antibody technetium-99m-BW 250/183 and indium-111 oxine-labelled leukocyte scintigraphy in inflammatory bowel disease

    Energy Technology Data Exchange (ETDEWEB)

    Segarra, I.; Roca, M.; Ricart, Y.; Mora, J.; Puchal, R.; Martin-Comin, J. (Hospital de Bella Vista, Barcelona (Spain). Servicio de Medicina Nuclear); Baliellas, C.; Vilar, L. (Hospital de Bella Vista, Barcelona (Spain). Servicio de Gastroenterologia)

    1991-09-01

    Thirty-three patients suspected of suffering from inflammatory bowel disease were studied. Autologous leukocytes were labelled with indium 111 oxine and re-injected simultaneously with 0.3-0.5 mg of {sup 99m}Tc-labelled granulocyte-specific monoclonal antibody BW 250/183. Two scans were obtained, the early scan 3-4 h post-injection (p.i.) and the late scan 18-24 h p.i. Using the endoscopy study as standard, the diagnostic accuracy of both agents was determined. Sensitivity, specificity and accuracy of {sup 111}In-scans was 88.8%, 100.0% and 93.7% at 4 h and 94.7%, 100.0% and 96.9% and 24 h, respectively. Concerning the results using antibodies, the values were 61.1%, 100.0% and 78.1% at 4 h and 78.9%, 92.8% and 84.8% at 24 h, respectively. Segmental analysis showed concordance in 89.3% and 93.3% of the cases at 4 and 24 h, respectively. Though less sensitive and less accurate than scanning employing indium 111 leukocytes, the BW 250/183 granulocyte-specific scintigraphy can be used for inflammatory bowel disease diagnosis and localization. (orig.).

  1. Integrating a 250 mL-spinner flask with other stirred bench-scale cell culture devices: a mass transfer perspective.

    Science.gov (United States)

    Vallejos, Jose R; Brorson, Kurt A; Moreira, Antonio R; Rao, Govind

    2011-01-01

    The bioprocess development cycle is a complex task that requires a complete understanding of the engineering of the process (e.g., mass transfer, mixing, CO(2) removal, process monitoring, and control) and its affect on cell biology and product quality. Despite their widespread use in bioprocess development, spinner flasks generally lack engineering characterization of critical physical parameters such as k(L)a, P/V, or mixing time. In this study, mass transfer characterization of a 250-mL spinner flask using optical patch-based sensors is presented. The results quantitatively show the effect of the impeller type, liquid filling volume, and agitation speed on the volumetric mass transfer coefficient (k(L)a) in a 250-mL spinner flask, and how they can be manipulated to match mass transfer capability at large culture devices. Thus, process understanding in spinner flasks can be improved, and these devices can be seamlessly integrated in a rational scale-up strategy from cell thawing to bench-scale bioreactors (and beyond) in biomanufacturing. PMID:21523928

  2. MONTHLY VARIABILITY OF TOTAL SUSPENDED MATTER (TSM MAPPING USING MODIS 250M TO SUPPORT MARINE CULTURE AT MOROTAI ISLAND, NORTH MALUKU

    Directory of Open Access Journals (Sweden)

    KOMANG IWAN SUNIADA

    2015-05-01

    Full Text Available This study was conducted to provide an information of Total Suspended Matter concentration and its monthly variability using dialy data of Terra/ Aqua MOD IS level 1 b with spatial resolution 250m imagery at Morotai Island, Northern Maluku. TSM is one of the water quality key parameter to support finding suitable area which is an important step for marine culture activity. Dialy Aqua/Terra MODIS level lb, 250m dataset was downloaded freely from Goddard Space Flight Center, LAADS Web (http ://ladsweb.nascom.nasa.gov/ and its contains information of calibrated radiance dan reflectance. TSM concentration derived using algorithm proposed by Trisakti et al, TSM (mg/I = 72743 (bl+b22 ·3551, where bl is remote sensing reflectance band 1 and b2 is remote sensing reflectance band 2. Further process is daily TSM data composited to produce monthly data to define the variability. GIS application technique based on apropriate environment condition for fish comodity are used to mapping suitable area concerning of TSM parameter. Suspended sediment concentrations derived from satellite data showed that the average range of 40-90 mg/I, with the highest suspended sediment concentration occurred in January and lowest in June

  3. A comparison of haemocoagulation tests in the experimental endotoxin model DIC and in rats whole-body irradiated by 250 Gy

    International Nuclear Information System (INIS)

    A comparison of results of tests performed with the endotoxin model of disseminated intravascular coagulation (DIC) and with irradiated groups of rats led to the conclusion that after whole-body irradiation with the high dose of 250 Gy, DIC occurs, in spite of the fact that the first stage, the hypercoagulation condition, can hardly be observed. In the experimental endotoxin model, an increase of activated partial thromboplastin test (APTT) values and prolongation of the thrombin time was observed up to 24 hours for two endotoxin doses. After both endotoxin doses, the fibrinogen level was transiently decreased with a subsequent increase. The fibrin monomers correspond to a decrease in the fibrinogen level. After the first dose, they were positive between the 3rd and 12th hours, and after the second dose, positivity was observed 6 hours after the application. The antithrombin III level was decreased after 12 hours for both endotoxin doses. The thrombocyte count was considerably reduced already from the 6th hour after administering endotoxin to the end of the experiment. Considerable changes in thrombocyte aggregation were observed only 3 hours after administering the second dose. When comparing the resulting values of these tests with values observed in irradiated animals, a certain agreement was found in the nature of the changes after exposure to 250 Gy. The fibrinogen level was transiently decreased 3 hours after irradiation, when considerable changes in the thrombocyte aggregation also occurred. (author) 5 figs., 17 refs

  4. Apparent molar volumes of aqueous calcium chloride to 250{degrees}C, 400 bars, and from molalities of 0.242 to 6.150

    Energy Technology Data Exchange (ETDEWEB)

    Oakes, C.S.; Bodnar, R.J. [Virginia Polytechnic Inst. and Univ., Blacksburg, VA (United States); Simonson, J.M. [Univ. of California, Berkeley, CA (United States)

    1995-09-01

    Relative densities of CaCl{sub 2}(aq) with 0.242 {le} m/(mol-kg{sup {minus}1}) {le} 6.150 were measured with vibrating-tube densimeters between 25 and 250{degrees}C and near 70 and 400 bars. Apparent molar volumes V{sub {null}} calculated from the measured density differences were represented with the Pitzer ion-interaction treatment, with appropriate expressions chosen for the temperature and pressure dependence of the virial coefficients of the model. It was found that the partial molar volume at infinite dilution V{sub {null}}{sup o}, and the second and third virial coefficients B{sup v} and C{sup v}, were necessary to represent V{sub {null}} near the estimated experimental uncertainty. The ionic-strength dependent {Beta}{sup 1}{sup v} term in the B{sup v} coefficient was included in the fit. The representation for V{sub {null}} has been integrated with respect to pressure to establish the pressure dependence of excess free energies over the temperature range studied. The volumetric data indicate that the logarithm of the mean ionic activity coefficient, ln {gamma}{plus_minus}(CaCl{sub 2}), increases by a maximum of 0.3 at 400 bars, 250{degrees}C, and 6 mol-kg{sup {minus}1} as compared with its value at saturation pressure.

  5. Ninety million years of orogenesis, 250 million years of quiescence and further orogenesis with no change in PT: Significance for the role of deformation in porphyroblast growth

    Indian Academy of Sciences (India)

    A A Shah; T H Bell

    2012-12-01

    In situ dating of monazite grains preserved as inclusions within foliations defining FIAs (foliation inflection/intersection axes preserved within porphyroblasts) contained within garnet, staurolite, andalusite and cordierite porphyroblasts provides a chronology of ages that matches the FIA succession for the Big Thompson region of the northern Colorado Rocky Mountains. FIA sets 1, 2 and 3 trending NE–SW, E–W and SE–NW were formed at 1760.5 ± 9.7, 1719.7 ± 6.4 and 1674 ± 11± Ma, respectively. For three samples where garnet first grew during just one of each of these FIAs, the intersection of Ca, Mg, and Fe isopleths in their cores indicate that these rocks never got above 4 kbars throughout the Colorado Orogeny. Furthermore, they remained around approximately the same depth for ∼250 million years to the onset of the younger Berthoud Orogeny at 1415 ± 16 Ma when the pressure decreased slightly as porphyroblasts formed with inclusion trails preserving FIA set 4 trending NNE–SSW. No porphyroblast growth occurred during the intervening ∼250 million years of quiescence, even though the PT did not change over this period. This confirms microstructural evidence gathered over the past 25 years that crenulation deformation at the scale of a porphyroblast is required for reactions to re-initiate and enable further growth.

  6. Crystal structures of iron bearing tetrahedrite and tennantite at 25 and 250 degrees C by means of Rietveld refinement of synchrotron data

    DEFF Research Database (Denmark)

    Friese, K.; Grzechnik, A.; Makovicky, E.;

    2008-01-01

    , increased Fe substitution is reflected in the increased tetrahedral 'Cu1'-S distance ('Cu1' is a site of Fe substitution) and Cu2-S distances. Cu2 was refined as a split position; the Cu2-Cu2 split about the plane of the S1(2)S2 triangle is about 0.56 and 0.65 angstrom for tetrahedrite and tennantite......, respectively. Cu2-Cu2 distances in the structure cavity are 2.8-2.9 angstrom. Between 25 and 250 degrees C, the lattice parameter a increased by 0.02-0.04 angstrom and the interatomic distances by 0.01 angstrom on an average. Thermal expansion coefficients of little-substituted samples are similar to those...... of unsubstituted samples, whereas thermal expansion appears to decrease with increasing substitution by Fe. The Cu2-Cu2 split increases at 250 degrees C by about 0.1 angstrom for tetrahedrite and by more than 0.15 angstrom for tennantite but the cage expansion is minimal so that the Cu2-Cu2 distances in the cavity...

  7. Biological, chemical and other data collected aboard the THOMAS G. THOMPSON during cruise TN250 in the Bering Sea from 2010-06-16 to 2010-07-15 (NODC Accession 0117398)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC accession 0117398 includes biological, chemical, optical and physical data collected aboard the THOMAS G. THOMPSON during cruise TN250 in the Bering Sea from...

  8. Photoexcitation of Yb-doped aluminosilicate fibers at 250 nm: evidence for excitation transfer from oxygen deficiency centers to Yb{sup 3+}

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, C. G. [Department of Electrical and Computer Engineering, University of Illinois, Urbana, Illinois 61801 (United States); Present address: Laser and Optics Research Center, USAF Academy, Colorado Springs, Colorado 80840 (United States); Keister, K. E.; Dragic, P. D.; Eden, J. G. [Department of Electrical and Computer Engineering, University of Illinois, Urbana, Illinois 61801 (United States); Croteau, A. [INO, 2740 Einstein Street, Quebec City, Quebec G1P 4S4 (Canada)

    2010-10-15

    Emission spectra in the {approx}240-1100 nm wavelength region as well as the temporally resolved decay of Yb{sup 3+} and point defect spontaneous emission have been recorded when aluminosilicate optical fibers doped with Yb are irradiated with {approx}160 fs laser pulses having a central wavelength of {approx}250 nm (({Dirac_h}/2{pi}){omega}=5 eV). Photoexcitation of the fibers in this region of the deep ultraviolet (UV) provides access simultaneously to the Type II Si oxygen deficiency center (ODC), the non-bridging oxygen hole center (NBOHC: an oxygen-excess defect), and the Ge ODC. Emission from all of these defects in the ultraviolet and/or visible is observed, as is intense fluorescence at 976 nm from Yb{sup 3+}. Absorption measurements conducted in the {approx}230-265 nm region with a sequence of UV light-emitting diodes reveal a continuum peaking at {approx}248 nm and having a spectral width of {approx}18 nm (FWHM), confirming that the 250 nm laser pump is photoexciting predominantly the ODC. The temporal histories of the optically active defect and rare earth ion emission waveforms, in combination with time-integrated spectra, suggest that the Si ODC(II) triplet state directly excites Yb{sup 3+} as well as at least one other intrinsic defect in the silica network. Prolonged exposure of the Yb-doped fibers to 250 nm radiation yields increased Yb{sup 3+}, NBOHC, and Si ODC(II) singlet emission which is accompanied by a decline in Si ODC(II) triplet fluorescence, thus reinforcing the conclusion--drawn on the basis of luminescence decay constants--that the triplet state of Si ODC(II) is the immediate precursor to the NBOHC and is partially responsible for Yb ion emission at 976 nm. This conclusion is consistent with the observation that exposure of fiber to 5 eV radiation slightly suppresses ODC absorption in the {approx}240-255 nm region while simultaneously introducing an absorption continuum extending from 260 nm to below 235 nm (({Dirac_h}/2{pi

  9. Effect of magnetic field strength on NMR-based metabonomic human urine data. Comparative study of 250, 400, 500, and 800 MHz

    DEFF Research Database (Denmark)

    Bertram, Hanne Christine; Malmendal, Anders; Petersen, Bent O.;

    2007-01-01

    Metabonomic analysis of urine utilizing high-resolution NMR spectroscopy and chemometric techniques has proven valuable in characterizing the biochemical response to an intervention. To assess the effect of magnetic field strength on information contained in NMR-based metabonomic data sets, 1H NMR...... the ability of the 1H spectra acquired at various field strengths to identify possible spectral differences and discriminate between pre- and postintervention samples. The loadings from PLS-DA contained the same spectral regions, implying that the same metabolites were involved in the discrimination...... independent of magnetic field strength. The investigation revealed a strong increase in prediction performance and thereby spectral information content when increasing the magnetic field strength from 250 to 500 MHz, while from 500 to 800 MHz the increase was less pronounced....

  10. Effect of 4-(N,N-diethylamino)benzaldehyde thiosemicarbazone on the corrosion of aged 18 Ni 250 grade maraging steel in phosphoric acid solution

    International Nuclear Information System (INIS)

    Highlights: → DEABT as corrosion inhibitor for maraging steel in phosphoric acid. → Inhibition efficiency increases with increase in inhibitor concentration. → Inhibition efficiency decreases with increase in temperature. → Adsorption obeys Langmuir adsorption isotherm. - Abstract: 4-(N,N-diethylamino)benzaldehyde thiosemicarbazone (DEABT) was studied for its corrosion inhibition property on the corrosion of aged 18 Ni 250 grade maraging steel in 0.67 M phosphoric acid at 30-50 deg. C by potentiodynamic polarization, EIS and weight loss techniques. Inhibition efficiency of DEABT was found to increase with the increase in DEABT concentration and decrease with the increase in temperature. The activation energy Ea and other thermodynamic parameters (ΔGads0, ΔHads0, ΔSads0) have been evaluated and discussed. The adsorption of DEABT on aged maraging steel surface obeys the Langmuir adsorption isotherm model and the inhibitor showed mixed type inhibition behavior.

  11. Study of the pitting and repassiv,tion corrosion potential of zicaloy-4 halides solutions at 250C and several pH

    International Nuclear Information System (INIS)

    The electrochemical behaviour of Zircaloy-4 electrode in chloride, bromide and iodide acid solution was investigated at 250C employing stationary, quasi-stationary and potentiodynamic techniques. The results show that the pitting and repassivation potentials are independent on pH but both are dependent on halice concentration, following linear relation ships in these cases. It is also possible to correlate the pitting potential with the ionic radius of the anions, allowing thus to establish an order in their agressive properties. This order was extrapolated for fluoride ion and further experimental measurements show that the corrosion potential of Zircaloy-4 in acid or neutra solution of this ion (which undergoes active dissolution) is coincident with that predicted from the Ep v/s ionic radius determined for the other halides. (Author)

  12. A cross section measurement of charm hyperons Ξc+ and Ξc0 in 250 GeV p/K/π-nucleon interactions

    International Nuclear Information System (INIS)

    Fermilab Experiment 769 used a charge-selected, hadron beam of mean energy 250 GeV/c, composed of pions, kaons, and protons, impinging on beryllium, aluminum, copper and tungsten targets. Using a sample of approximately 4000 Ξs- → Λ0π- decays, measurements of the charm baryon forward cross sections times branching ratio π±N → Ξc+X and π±N → Ξc0X are presented. Upper limits on α x BR are also determined for the states Ξc+ → Ξs-π+π+ and Ξc0 → Ξs-π+ produced in (p, π+, π-, K+, K-)-nucleon interactions

  13. 贵在同乐——纽卡斯尔盖茨黑德承办Brewin Dolphin公司250周年庆典

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    生日会,更是感谢会 Brewin Dolphin公司是英国最大的独立私人客户投资管理公司,希望办一场250周年庆祝会。公司决定在纽卡斯尔市承办这次庆祝会,因为该市是公司第三大办事处所在地。场地选择在The Sage Galeshead,这是一座能容纳700人的场馆,这个场馆坐落在纽卡斯尔盖茨黑德的泰恩河畔,是一座地标性的场馆,专门为音乐会和艺术展设计的。

  14. Low-temperature (T = 250-400 K) oxygen adsorption on YBa sub 2 Cu sub 3 O sub 6 sub . sub 9 ceramics

    CERN Document Server

    Kuznetsov, V N

    2001-01-01

    The oxygen adsorption on the YBa sub 2 Cu sub 3 O sub 6 sub . sub 9 ceramics is studied within the temperature range of 250-400 K through the method of the thermodesorption (TD) mass-spectroscopy. It is established, that depending on the temperature (T subalpha) the O sub 2 adsorption leads to formation of two (gamma 1 and gamma 2 at the T subalpha = 350 K) adsorption forms. The associative desorption mechanism with the activation energy (0.63 +- 0.08) (gamma 1) and (1.13 +- 0.02) eV (gamma 2) is the most probable one for both forms. The model, qualitatively describing the oxygen sorption on the ceramics, the initial stage whereof is constituted by the gamma 2 adsorption form formation, is proposed

  15. Diseño y desarrollo de un chasis de una motocicleta de 250cc para la “II Competición Internacional MotoStudent”

    OpenAIRE

    García García, Ismael

    2013-01-01

    [SP]El objeto de este proyecto es el diseño y cálculo estructural del chasis de una motocicleta de competición, así como su desarrollo y posterior fabricación. Concretamente se trata de una motocicleta de 250 c.c. y 4 Tiempos, que posteriormente participará en el circuito de Motorland (Aragón) en la “II Competición Internacional MotoStudent”. Por tanto, el objetivo será encontrar el diseño más óptimo de chasis que permita obtener una motocicleta lo más competitiva posible. S...

  16. Change in land use in the Phoenix (1:250,000) Quadrangle, Arizona between 1970 and 1972: Successful use of proposed land use classification system

    Science.gov (United States)

    Place, J. L.

    1973-01-01

    Changes in land use in the Phoenix (1:250,000 scale) Quadrangle in Arizona have been mapped using only the images from ERTS-1, tending to verify the utility of a land use classification system proposed for use with ERTS images. The period of change investigated was from November 1970 to late summer or early fall, 1972. Seasonal changes also were studied using successive ERTS images. Types of equipment used to aid interpretation included a color additive viewer, a twenty-power magnifier, a density slicer, and a diazo copy machine for making ERTS color composites in hard copy. Types of changes detected have been: (1) cropland or rangeland developed for new residential areas; (2) rangeland converted to new cropland; and (3) possibly new areas of industrial or commercial development. A map of land use previously compiled from air photos was updated in this manner.

  17. A Dependence Study of $\\Xi^{*0}$ and $\\bar{\\Xi}^{*0}$ in 250 GeV/c $\\pi^-$. $K^-$ -nucleon Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Seixas de Rezende, Fabio Antonio; /Rio de Janeiro, CBPF

    2005-04-01

    A direct measurement of the mass number (A) dependence of the production of the hyperon {Xi}*{sup 0} and its opposite {bar {Xi}}*{sup 0} in {pi}{sup -}, K{sup -} beam-nucleon interactions at 250 GeV/c is reported. The data derive from the experiment E769 at Fermilab. The results were obtained for different targets: Be, Al, Cu and W. It was observed the data are found to be well described by the parametrization {sigma}{sub A} = {sigma}{sub 0}A{sup {alpha}}, {alpha} being calculated for different beams. The results obtained are compared with those results of E769 experiment. The results shown here are preliminary.

  18. Cytological effect of Tilt 250 EC in the successive phases of the Triticale rust disease process caused by Puccinia recondita f. sp. tritici

    Directory of Open Access Journals (Sweden)

    Krystyna Brzezicka-Szymczyk

    2014-02-01

    Full Text Available The disease process caused by rust (Puccinia recondita f. sp. tritici in Triticale (Triticale-Wittmack cv. Bolero and the effect of the application of the propikonazole - Tilt 250 EC are described. In plants not protected chemically one could observe the whole pathogen developmental cycle ending with the appearance of uredinia with urediniospores. The highest pathogen susceptibility to chemical agent was observed at the time of inoculation, during incubation and at the beginning of the actual disease. By inhibiting the ergosterol biosynthesis in the fungus cells the preparation (propikonazole inhibited the development of the intra- and extracellular mycelium. The mycelium degeneration manifested itself by the irregular growth of intercellular hyphae, perforation of septa, homogenization of protoplasts and cell collapse. The thickening of the cell wall, modification of the perihaustorial space and protoplast obliteration were observed in the haustoria.

  19. Evidence for collective expansion in light-particle emission following Au+Au collisions at 100, 150 and 250 A.MeV

    International Nuclear Information System (INIS)

    Light-particle emission from Au+Au collisions has been studied in the bombarding-energy range 100-250A.MeV, using ΔE-ER telescopes in coincidence with the FOPI detector in its phase I configuration. Center-of-mass energy spectra have been measured for Z=1, 2 isotopes emitted in central collisions at CM polar angles between 60 circle and 90 circle. Evidence for a collective expansion is reported, on the basis of the mean kinetic energies of hydrogen isotopes. Comparison is presented with statistical calculations (WIX code). For CM kinetic energy spectra, fair agreement is found between data and a recently developed transport model. ((orig.))

  20. X-ray grating spectrometer for opacity measurements in the 50 eV to 250 eV spectral range at the LULI 2000 laser facilitya)

    Science.gov (United States)

    Reverdin, Charles; Thais, Frédéric; Loisel, Guillaume; Busquet, M.; Bastiani-Ceccotti, S.; Blenski, T.; Caillaud, T.; Ducret, J. E.; Foelsner, W.; Gilles, D.; Gilleron, F.; Pain, J. C.; Poirier, M.; Serres, F.; Silvert, V.; Soullie, G.; Turck-Chieze, S.; Villette, B.

    2012-10-01

    An x-ray grating spectrometer was built in order to measure opacities in the 50 eV to 250 eV spectral range with an average spectral resolution ⟨E/δE⟩ ˜ 50. It has been used at the LULI-2000 laser facility at École Polytechnique (France) to measure the Δn = 0, n = 3 transitions of several elements with neighboring atomic number: Cr, Fe, Ni, and Cu in the same experimental conditions. Hence a spectrometer with a wide spectral range is required. This spectrometer features one line of sight looking through a heated sample at backlighter emission. It is outfitted with one toroidal condensing mirror and several flat mirrors cutting off higher energy photons. The spectral dispersion is obtained with a flatfield grating. Detection consists of a streak camera sensitive to soft x-ray radiation. Some experimental results showing the performance of this spectrometer are presented.

  1. X-ray grating spectrometer for opacity measurements in the 50 eV to 250 eV spectral range at the LULI 2000 laser facility

    Energy Technology Data Exchange (ETDEWEB)

    Reverdin, Charles; Caillaud, T.; Gilleron, F.; Pain, J. C.; Silvert, V.; Soullie, G.; Villette, B. [CEA, DAM, DIF, 91297 Arpajon (France); Thais, Frederic; Loisel, Guillaume; Blenski, T.; Poirier, M. [CEA, DSM, IRAMIS, Service Photons, Atomes et Molecules, 91191 Gif-sur-Yvette (France); Busquet, M. [ARTEP Inc, Ellicott City, Maryland 21042 (United States); Bastiani-Ceccotti, S.; Serres, F. [LULI, Ecole Polytechnique, CNRS, CEA, UPMC, route de Saclay, 91128 Palaiseau (France); Ducret, J. E. [CELIA, UMR5107, CEA, CNRS, Universite de Bordeaux, 33400 Talence (France); Foelsner, W. [Max Planck Instituet fuer Quantum Optik, 85748 Garching (Germany); Gilles, D.; Turck-Chieze, S. [CEA, DSM, IRFU, Service d' astrophysique, 91191 Gif-sur-Yvette (France)

    2012-10-15

    An x-ray grating spectrometer was built in order to measure opacities in the 50 eV to 250 eV spectral range with an average spectral resolution {approx} 50. It has been used at the LULI-2000 laser facility at Ecole Polytechnique (France) to measure the {Delta}n = 0, n = 3 transitions of several elements with neighboring atomic number: Cr, Fe, Ni, and Cu in the same experimental conditions. Hence a spectrometer with a wide spectral range is required. This spectrometer features one line of sight looking through a heated sample at backlighter emission. It is outfitted with one toroidal condensing mirror and several flat mirrors cutting off higher energy photons. The spectral dispersion is obtained with a flatfield grating. Detection consists of a streak camera sensitive to soft x-ray radiation. Some experimental results showing the performance of this spectrometer are presented.

  2. X-ray grating spectrometer for opacity measurements in the 50 eV to 250 eV spectral range at the LULI 2000 laser facility.

    Science.gov (United States)

    Reverdin, Charles; Thais, Frédéric; Loisel, Guillaume; Busquet, M; Bastiani-Ceccotti, S; Blenski, T; Caillaud, T; Ducret, J E; Foelsner, W; Gilles, D; Gilleron, F; Pain, J C; Poirier, M; Serres, F; Silvert, V; Soullie, G; Turck-Chieze, S; Villette, B

    2012-10-01

    An x-ray grating spectrometer was built in order to measure opacities in the 50 eV to 250 eV spectral range with an average spectral resolution ∼ 50. It has been used at the LULI-2000 laser facility at École Polytechnique (France) to measure the Δn = 0, n = 3 transitions of several elements with neighboring atomic number: Cr, Fe, Ni, and Cu in the same experimental conditions. Hence a spectrometer with a wide spectral range is required. This spectrometer features one line of sight looking through a heated sample at backlighter emission. It is outfitted with one toroidal condensing mirror and several flat mirrors cutting off higher energy photons. The spectral dispersion is obtained with a flatfield grating. Detection consists of a streak camera sensitive to soft x-ray radiation. Some experimental results showing the performance of this spectrometer are presented. PMID:23126955

  3. European Collaboration for High-Resolution Measurements of Neutron Cross Sections between 1 MeV and 250 MeV

    CERN Multimedia

    Leal, L C; Kitis, G; Guber, K H; Yuasa nakagawa, K; Koehler, P E; Quaranta, A

    2002-01-01

    The experimental determination of neutron cross section data has always been of primary importance in Nuclear Physics. Many of the salient features of nuclear levels and densities can be determined from the resonant structure of such cross sections and of their decay scheme. An associated importance of precise neutron induced reaction cross sections has resulted from the worldwide interest in Accelerator Driven Systems (ADS) that has emerged at CERN and elsewhere. Many applications, such as accelerator-based transmutation of nuclear waste, energy amplification medical research, astrophysical applications and also fusion research require nuclear data that quantitatively and qualitatively go beyond the presently available traditional evaluation.\\\\ \\\\We consider a spallation driven TOF facility at the CERN-PS with an unprecedented neutron flux (1000 times the existing ones) in the broad energy range between 1 eV and 250 MeV and with very high energy resolution. The present concept for an intense neutron source m...

  4. Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells

    Science.gov (United States)

    Amara, Salem; Douki, Thery; Ravanat, Jean-Luc; Garrel, Catherine; Guiraud, Pascale; Favier, Alain; Sakly, Mohsen; Ben Rhouma, Khémais; Abdelmelek, Hafedh

    2007-02-01

    The aim of this study was to investigate the effect of static magnetic field (SMF) exposure in antioxidant enzyme activity, the labile zinc fraction and DNA damage in THP1 cells (monocyte line). Cell culture flasks were exposed to SMF (250 mT) during 1 h (group 1), 2 h (group 2) and 3 h (group 3). Our results showed that cell viability was slightly lower in SMF-exposed groups compared to a sham exposed group. However, SMF exposure failed to alter malondialdehyde (MDA) concentration (+6%, p > 0.05) and glutathione peroxidase (GPx) (-5%, p > 0.05), catalase (CAT) (-6%, p > 0.05) and superoxide dismutase (SOD) activities (+38%, p > 0.05) in group 3 compared to the sham exposed group. DNA analysis by single cell gel electrophoresis (comet assay) revealed that SMF exposure did not exert any DNA damage in groups 1 and 2. However, it induced a low level of DNA single strand breaks in cells of group 3. To further explore the oxidative DNA damage, cellular DNA for group 3 was isolated, hydrolyzed and analysed by HPLC-EC. The level of 8-oxodGuo in this group remained unchanged compared to the sham exposed group (+6.5%, p > 0.05). Cells stained with zinc-specific fluorescent probes zinpyr-1 showed a decrease of labile zinc fraction in all groups exposed to SMF. Our data showed that SMF exposure (250 mT, during 3 h) did not cause oxidative stress and DNA damage in THP1 cells. However, SMF could alter the intracellular labile zinc fraction.

  5. Rutile solubility in NaF-NaCl-KCl-bearing aqueous fluids at 0.5-2.79 GPa and 250-650 °C

    Science.gov (United States)

    Tanis, Elizabeth A.; Simon, Adam; Zhang, Youxue; Chow, Paul; Xiao, Yuming; Hanchar, John M.; Tschauner, Oliver; Shen, Guoyin

    2016-03-01

    The complex nature of trace element mobility in subduction zone environments is thought to be primarily controlled by fluid-rock interactions, episodic behavior of fluids released, mineral assemblages, and element partitioning during phase transformations and mineral breakdown throughout the transition from hydrated basalt to blueschist to eclogite. Quantitative data that constrain the partitioning of trace elements between fluid(s) and mineral(s) are required in order to model trace element mobility during prograde and retrograde metamorphic fluid evolution in subduction environments. The stability of rutile has been proposed to control the mobility of HFSE during subduction, accounting for the observed depletion of Nb and Ta in arc magmas. Recent experimental studies demonstrate that the solubility of rutile in aqueous fluids at temperatures >700 °C and pressures range of temperature and pressure than is currently available. In this study, new experimental data are presented that quantify the solubility of rutile in aqueous fluids from 0.5 to 2.79 GPa and 250 to 650 °C. Rutile solubility was determined by using synchrotron X-ray fluorescence to measure the concentration of Zr in an aqueous fluid saturated with a Zr-bearing rutile crystal within a hydrothermal diamond anvil cell. At the PT conditions of the experiments, published diffusion data indicate that Zr is effectively immobile (log DZr ∼10-25 m2/s at 650 °C and ∼10-30 m2/s at 250 °C) with diffusion length-scales of 4th power of the F- concentration. These new data are consistent with observations from field studies of exhumed terranes that indicate that rutile is soluble in complex aqueous fluids, and that fluid composition is the primary control on rutile solubility and HFSE mobility.

  6. Application of the Cavity theory in the calibration of the powder TLD-100 for energies of 60 Co, 137 Cs, 192 Ir and RX 50, 250 k Vp

    International Nuclear Information System (INIS)

    A powder lot TLD-100 (LiF:Mg,Ti) in absorbed dose terms in water Dw for the following radiation sources: 60 Co, 137 Cs and RX 50 and 250 k Vp is calibrated; to continuation is made a lineal interpolation of the TLD response in function of the effective energy of the sources to calibrate a source of 192 Ir. The calibration of those fields in Dw are carried out with aid of the Bragg-Gray cavity theory, the one which finds implicit in the following protocols: IAEA-TRS 398 for the 60 Co and the AAPM TG61 for X Rays of 50 and 250 k Vp. Additionally the AAPM protocol TG43 to determine the Dw in function of the kerma intensity Sk in the case of the 137 Cs is used. The calibration curves for the response of the TLD-100 RTLD vs Dw, corresponding to each one of the sources already mentioned are constructed. The RTLD vs Dw by least heavy square by means of a second order polynomial that corrects the supralineality of the response is adjusted. The curves are validated by lack of LOF adjustment and by the Anderson Darling normality test. Later the factors of sensitivity (Fs) for the sources of 192 Ir: Micro Selectron and Vari Source are interpolated, used respectively in the A and B hospitals for treatments of brachytherapy of high dose rate (HDR), the expanded uncertainties associated to the Dw and Fs are also determined. Finally, an acrylic phantom and a couple of capsules are already sent to the hospitals mentioned, to verify a nominal Dw of 2 Gy, in a case an underestimate in 5.5% in the imparted Dw and in other an overestimation in a range of -1.5 to -8.0% was obtained. The obtained results in this work establish the bases for the development of a national dosimetric quality control program for brachytherapy of HDR with sources of 192 Ir. (Author)

  7. Suggestion on Minimum Curved Radium and Curved Length Standard for Newly Built Passenger-Freight Railway with Speed of 250 km/h%对新建时速250 km客货共线铁路最小曲线半径与缓和曲线长度标准的建议

    Institute of Scientific and Technical Information of China (English)

    周惟俊

    2007-01-01

    结合远期提速的可能性与运输模式,对近期实行高中速客货车250/120 km/h匹配混跑,最终实现高中速客货车300/160 km/h匹配混跑或全高速300 km/h的速度目标值分别进行最小曲径半径与缓和曲线长度的计算与分析,并提出相应速度匹配的设计标准.

  8. Lacaille : Lacaille 250 years on

    Science.gov (United States)

    Warner, Brian

    2002-04-01

    Brian Warner, Department of Astronomy, University of Cape Town, tells the story of Nicolas Louis de Lacaille's sojourn in South Africa. Two hundred and fifty years ago French astronomer Nicolas Louis de la Caille spent two years at the Cape of Good Hope, carrying out astronomical and geodetic observations that had long-lasting repercussions. His measurements of the positions of nearly 10 000 southern stars led to the definition of the southern constellations which are used to this day; his discrepant measurement of the radius of the Earth provided a challenge that took much 19th-century labour to rectify, but led to an accurate trigonometric survey of South Africa that would otherwise not have occurred until much later.

  9. Three-micron extinction of the Titan haze in the 250-700 km altitude range: Possible evidence of a particle-aging process

    Science.gov (United States)

    Courtin, Régis; Kim, Sang Joon; Bar-Nun, Akiva

    2015-01-01

    Context. The chemical nature of the Titan haze is poorly understood. The investigation carried out by the Cassini-Huygens suite of instruments is bringing new insights into this question. Aims: This work aims at deriving the vertical variation of the spectral structure of the 3.3-3.4 μm absorption feature of the Titan haze from Cassini VIMS solar occultation data recorded between 250 and 700 km altitude. Methods: We computed the transmittance of Titan's atmosphere using a spherical shell model and a radiative transfer code including the influence of CH4, CH3D, and C2H6, as well as the effects of absorption and scattering by the haze particles. We derived the haze extinction from a comparison of the synthetic spectra with the VIMS solar occultation spectra. Results: We find a marked change in the relative amplitudes of the 3.33 and 3.38 μm features, which are characteristic of aromatic (double C=C chains or rings) or aliphatic (single C-C chains) structural groups, respectively. The pseudo-ratio of aromatics to aliphatics (uncorrected for the absolute band strengths) varies from 3.3 ± 1.9 at 580-700 km to 0.9 ± 0.1 at 350-450 km, and is 0.5 ± 0.1 around 250 km. The structural change from the aromatic to the aliphatic type between 580 and 480 km appears to correspond to a spontaneous aging of the particles - a transition between unannealed and hardened particles - while the further decrease of the pseudo-ratio of aromatics to aliphatics below 480 km may be related to the coating of the core particles by condensates such as heavy alkanes. VIMS transmission spectra data are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/573/A21

  10. [Upconversion and mid-infrared fluorescence properties of Ho3+/Yb3+ co-doped 50SiO2-50PbF2 glass ceramic].

    Science.gov (United States)

    Zhang, Xiao-guang; Ren, Guo-zhong; Yang, Huai

    2014-08-01

    In the present paper, the upconversion and mid-infrared fluorescence properties of Ho3+/Yb3+ co-doped 50SiO2- 50PbF2 glass ceramic (GC) were studied. The GC has the following composition (in mol%): 50SiO2-50PbF2-1YbF3-0. 5HoF3. The mixtures of about 10 g were placed in a corundum crucible and melted at 1000 degrees C for 15 min in a SiC electric furnace in air and then poured on a brass plate. The GCs were obtained just by heat treatment at 450 degrees C. The X-ray diffraction pattern of the GC indicates that very small size crystals were precipitated in the precursor glass by heat treatment. The GCs have as high transmittance as glasses. The GCs have higher absorption cross section and narrower absorption peaks compared to the corresponding glasses, indicating that fluoride is doped with Ho ions. The Judd-Ofelt intensity parameters were determined from the absorption spectrum and Judd-Ofelt theory. The omega2 value is 0.17 x 10(-20) cm2 lower than that of fluoride glass ZBLA (2.28 x 10(-20) cm2), because of Ho3+ doping in PbF2 microcrystal. The intense green upconversion light was observed in Ho3+/Yb3+ co-doped 50SiO2-50PbF2 GCs excited by 980 nm laser diode. A main emission band centered around 540 nm (green), and three week emission bands centered around 420 nm(violet), 480 nm (blue), and 650 nm (red) which correspond to the Ho3+ : ((5)F4-->(5)I8) ((5)G-->(5)I8), ((8)K3--(5)I8) and ((5)F5-->(5)I8) transitions, respectively, were simultaneously observed in GCs. Compared with the glass sample, GCs have significantly intension in the green and blue upconversion fluorescence, and not significant change in the red upconversion fluorescence. Those changes are because that Ho ion in GCs locates in lower phonon energy environment than in glasses. Lower phonon energy can make the nonradiative relaxation rate reduce, which improves the green light upconversion efficiency, at the same time reduces the population of the intermediate energy level ((5)I7) of the red light

  11. Characterization of neoformed illite from hydrothermal experiments at 250 C and P{sub v,soln}: An HRTEM/ATEM study

    Energy Technology Data Exchange (ETDEWEB)

    Yates, D.M.; Rosenberg, P.E. [Washington State Univ., Pullman, WA (United States). Dept. of Geology

    1998-11-01

    Solid products from hydrothermal experiments conducted at 250 C and P{sub v,soln} were characterized by powder X-ray diffraction (XRD) and ATEM/HRTEM. Experiments were conducted with muscovite, kaolinite, and quartz or amorphous silica in 2M KCl solutions for 43 to 176 d. Post-experiment solution compositions lie either within the illite(0.88 K) stability field or on the illite(0.88 K)-kaolinite or illite(0.88 K)-diaspore univariant boundaries in log (a{sub K}{sup +}/a{sub H}{sup +}) vs. log a{sub H{sub 4}SiO{sub 4}} activity space. Transmission electron microscopy (TEM) observations of muscovite grain edges reveal the neoformation of illite crystals with a range of compositions (ATEM) from 0.31 to 0.89 K/O{sub 10}(OH){sub 2}. The range of K-contents appears to narrow toward 0.88 K/O{sub 10}(OH){sub 2} with increased experiment duration. HRTEM suggests the presence of 2 to 11 layer fundamental particles composed of illitic layers with 10 A periodicity. Fundamental particle thicknesses increase toward an average of 8 layers/particle with increased experiment duration. In the longer duration experiments, fundamental particle thicknesses were normally distributed about thicknesses of 4 and 8 layers, whereas fundamental particles with thicknesses <4 layers were common in a shorter duration experiment. The compositions and structure of the illites are consistent with the multiphase model, which states that the smectite-to-illite transition occurs through the step-wise formation of solubility-controlling phases consisting of fundamental particles with thicknesses of 1, 2, 4, and {le}8 layers. The increase in K-content and fundamental particle thickness with the extent of reaction suggests that the illite crystals underwent a prograde reaction culminating in the formation of end-member illite [0.88 K/O{sub 10}(OH){sub 2}]. This reaction, in conjunction with the previously observed, retrograde reaction from muscovite to end-member illite, demonstrates the stability of end

  12. Oxygen and hydrogen isotope fractionation in serpentine-water and talc-water systems from 250 to 450 °C, 50 MPa

    Science.gov (United States)

    Saccocia, Peter J.; Seewald, Jeffrey S.; Shanks, Wayne C., III

    2009-01-01

    Oxygen and hydrogen isotope fractionation factors in the talc–water and serpentine–water systems have been determined by laboratory experiment from 250 to 450 °C at 50 MPa using the partial exchange technique. Talc was synthesized from brucite + quartz, resulting in nearly 100% exchange during reaction at 350 and 450 °C. For serpentine, D–H exchange was much more rapid than 18O–16O exchange when natural chrysotile fibers were employed in the initial charge. In experiments with lizardite as the starting charge, recrystallization to chrysotile enhanced the rate of 18O–16O exchange with the coexisting aqueous phase. Oxygen isotope fractionation factors in both the talc–water and serpentine–water systems decrease with increasing temperature and can be described from 250 to 450 °C by the relationships: 1000 ln  = 11.70 × 106/T2 − 25.49 × 103/T + 12.48 and 1000 ln  = 3.49 × 106/T2 − 9.48 where T is temperature in Kelvin. Over the same temperature interval at 50 MPa, talc–water D–H fractionation is only weakly dependent on temperature, similar to brucite and chlorite, and can be described by the equation: 1000 ln  = 10.88 × 106/T2 − 41.52 × 103/T + 5.61 where T is temperature in Kelvin. Our D–H serpentine–water fractionation factors calibrated by experiment decrease with temperature and form a consistent trend with fractionation factors derived from lower temperature field calibrations. By regression of these data, we have refined and extended the D–H fractionation curve from 25 to 450 °C, 50 MPa as follows: 1000 ln  = 3.436 × 106/T2 − 34.736 × 103/T + 21.67 where T is temperature in Kelvin. These new data should improve the application of D–H and 18O–16O isotopes to constrain the temperature and origin of hydrothermal fluids responsible for serpentine formation in a variety of geologic settings.

  13. Effects of magnetic field and hydrostatic pressure on the isothermal martensitic transformation in an Fe-25.0Ni-4.0Cr alloy

    International Nuclear Information System (INIS)

    Effects of magnetic fields and hydrostatic pressures on the isothermal martensitic transformation, whose nose temperature is about 140K, in an Fe-25.0Ni-4.0Cr alloy (mass%) has been examined by applying magnetic fields up to 30MA/m and hydrostatic pressures up to 1.5GPa. The obtained results are the following: The martensitic transformation is induced instantaneously (less than 20μsec.) under pulsed magnetic fields higher than a critical field over a wide temperature range between 4.2 and 200K. The critical magnetic field increases with increasing temperature, and the relation between critical magnetic field and temperature is in good agreement with the one calculated by the equation previously derived by the authors. The T T T diagram under static magnetic field shows a lower nose temperature and a shorter incubation time than that under no external magnetic field, while the T T T diagram under hydrostatic pressure shows a higher nose temperature and a longer incubation time than that under no external hydrostatic pressure. These results are well explained by the new phenomenological theory, which gives a unified explanation on the isothermal and athermal kinetics of martensitic transformations previously constructed by the authors. (orig.)

  14. The mechanism by which P250L mutation impairs flavivirus-NS1 dimerization: an investigation based on molecular dynamics simulations.

    Science.gov (United States)

    Oliveira, Edson R A; de Alencastro, Ricardo B; Horta, Bruno A C

    2016-09-01

    The flavivirus non-structural protein 1 (NS1) is a conserved glycoprotein with as yet undefined biological function. This protein dimerizes when inside infected cells or associated to cell membranes but also forms lipid-associated hexamers when secreted to the extracellular space. A single amino acid substitution (P250L) is capable of preventing the dimerization of NS1 resulting in lower virulence and slower virus replication. In this work, based on molecular dynamics simulations of the dengue-2 virus NS1 [Formula: see text]-ladder monomer as a core model, we found that this mutation can induce several conformational changes that importantly affect critical monomer-monomer interactions. Based on additional simulations, we suggest a mechanism by which a highly orchestrated sequence of events propagate the local perturbations around the mutation site towards the dimer interface. The elucidation of such a mechanism could potentially support new strategies for rational production of live-attenuated vaccines and highlights a step forward in the development of novel anti-flavivirus measures. PMID:27324799

  15. A continuous 250,000 yr record of oxygen and carbon isotopes in ostracode and bulk-sediment carbonate from Bear Lake, Utah-Idaho

    Science.gov (United States)

    Bright, Jordon; Kaufman, D.S.; Forester, R.M.; Dean, W.E.

    2006-01-01

    Oxygen and carbon isotopes from a continuous, 120-m-long, carbonate-rich core from Bear Lake, Utah-Idaho, document dramatic fluctuations in the hydrologic budget of the lake over the last 250,000 yr. Isotopic analyses of bulk sediment samples capture millennial-scale variability. Ostracode calcite was analyzed from 78 levels, mainly from the upper half of the core where valves are better preserved, to compare the isotopic value of purely endogenic carbonate with the bulk sediment, which comprises both endogenic and detrital components. The long core exhibits three relatively brief intervals with abundant endogenic aragonite (50??10%) and enriched ??18O and ??13C. These intervals are interpreted as warm/dry periods when the lake retracted into a topographically closed basin. We correlate these intervals with the interglacial periods of marine oxygen-isotope stages 1, 5e, and 7a, consistent with the presently available geochronological control. During most of the time represented by the core, the lake was fresher than the modern lake, as evidenced by depleted ??18O and ??13C in bulk-sediment carbonate. ?? 2006 Elsevier Ltd. All rights reserved.

  16. The Lassa fever virus L gene: nucleotide sequence, comparison, and precipitation of a predicted 250 kDa protein with monospecific antiserum

    Science.gov (United States)

    Lukashevich, Igor S.; Djavani, Mahmoud; Shapiro, Keli; Sanchez, Anthony; Ravkov, Eugene; Nichol, Stuart T.; Salvato, Maria S.

    2008-01-01

    The large (L) RNA segment of Lassa fever virus (LAS) encodes a putative RNA-dependent RNA polymerase (RdRp or L protein). Similar to other arenaviruses, the LAS L protein is encoded on the genome-complementary strand and is predicted to be 2218 amino acids in length (253 kDa). It has an unusually large non-coding region adjacent to its translation start site. The LAS L protein contains six motifs of conserved amino acids that have been found among arenavirus L proteins and core RdRp of other segmented negative-stranded (SNS) viruses (Arena-, Bunya- and Orthomyxoviridae). Phylogenetic analyses of the RdRp of 20 SNS viruses reveals that arenavirus L proteins represent a distinct cluster divided into LAS–lymphocytic choriomeningitis and Tacaribe–Pichinde virus lineages. Monospecific serum against a synthetic peptide corresponding to the most conserved central domain precipitates a 250 kDa product from LAS and lymphocytic choriomeningitis virus-infected cells. PMID:9049403

  17. A fuel cell operating between room temperature and 250 °C based on a new phosphoric acid based composite electrolyte

    Science.gov (United States)

    Lan, Rong; Xu, Xiaoxiang; Tao, Shanwen; Irvine, John T. S.

    A phosphoric acid based composite material with core-shell microstructure has been developed to be used as a new electrolyte for fuel cells. A fuel cell based on this electrolyte can operate at room temperature indicating leaching of H 3PO 4 with liquid water is insignificant at room temperature. This will help to improve the thermal cyclability of phosphoric acid based electrolyte to make it easier for practical use. The conductivity of this H 3PO 4-based electrolyte is stable at 250 °C with addition of the hydrophilic inorganic compound BPO 4 forming a core-shell microstructure which makes it possible to run a PAFC at a temperature above 200 °C. The core-shell microstructure retains after the fuel cell measurements. A power density of 350 mW/cm 2 for a H 2/O 2 fuel cell has been achieved at 200 °C. The increase in operating temperature does not have significant benefit to the performance of a H 2/O 2 fuel cell. For the first time, a composite electrolyte material for phosphoric acid fuel cells which can operate in a wide range of temperature has been evaluated but certainly further investigation is required.

  18. Evolution of structure, phase composition, and x-ray reflectivity of multilayer mirrors mo-(B + C) after annealing at 250-1100°c.

    Science.gov (United States)

    Kopilets, I A; Kondratenko, V V; Fedorenko, A I; Zubarev, E N; Poltseva, O V; Ponomarenko, A G; Lyakhovskaya, I I

    1996-01-01

    Structural, phase, and chemical stabilities of x-ray multilayer mirrors Mo-(B + C) with periods in the range 8-11.5 nm were studied at temperatures of 250-1100°C by small-angle and large-angle x-ray diffraction and electron microscopy methods. Two amorphizations at ~450 and ~750°C and two crystallizations at ~650 and ~850°C of Mo-based layers were observed, which were due to the formation of the molybdenum carbides MoC (hex), γ-MoC, and Mo2C instead of the metal Mo, and to the formation of the molybdenum borides MoB2 and Mo2B5 instead of molybdenum carbides, respectively. Both amorphizations of Mo-based layers were accompanied by smoothing of interfaces and by an increase of the multilayer x-ray reflectivity at λ = 0.154 nm. Both crystallizations of Mo-based layers promoted the development of interface roughness and a decrease of multilayer x-ray reflectivity. The destruction of Mo-(B + C) multilayers at ~ 1100°C was caused by the recrystallization of Mo2B5 layers.

  19. Current density and catalyst-coated membrane resistance distribution of hydro-formed metallic bipolar plate fuel cell short stack with 250 cm2 active area

    Science.gov (United States)

    Haase, S.; Moser, M.; Hirschfeld, J. A.; Jozwiak, K.

    2016-01-01

    An automotive fuel cell with an active area of 250 cm2 is investigated in a 4-cell short stack with a current and temperature distribution device next to the bipolar plate with 560 current and 140 temperature segments. The electrical conductivities of the bipolar plate and gas diffusion layer assembly are determined ex-situ with this current scan shunt module. The applied fuel cell consists of bipolar plates constructed of 75-μm-thick, welded stainless-steel foils and a graphitic coating. The electrical conductivities of the bipolar plate and gas diffusion layer assembly are determined ex-situ with this module with a 6% deviation in in-plane conductivity. The current density distribution is evaluated up to 2.4 A cm-2. The entire cell's investigated volumetric power density is 4.7 kW l-1, and its gravimetric power density is 4.3 kW kg-1 at an average cell voltage of 0.5 V. The current density distribution is determined without influencing the operating cell. In addition, the current density distribution in the catalyst-coated membrane and its effective resistivity distribution with a finite volume discretisation of Ohm's law are evaluated. The deviation between the current density distributions in the catalyst-coated membrane and the bipolar plate is determined.

  20. Geochemical provenance of anomalous metal concentrations in stream sediments in the Ashton 1:250,000 quadrangle, Idaho/Montana/Wyoming

    International Nuclear Information System (INIS)

    Stream-sediment samples from 1500 sites in the Ashton, Idaho/Montana/Wyoming 1:250,000 quadrangle were analyzed for 45 elements. Almost all samples containing anomalous concentrations (exceeding one standard deviation above the mean value of any element) were derived from drainage basins underlain by Quaternary rhyolite, Tertiary andesite or Precambrian gneiss and schist. Aluminum, barium, calcium, cobalt, iron, nickel, magnesium, scandium, sodium, strontium, and vanadium have no andesite provenance. Most anomalous manganese, europium, hafnium, and zirconium values were derived from Precambrian rocks. All other anomalous elemental concentrations are related to Quaternary rhyolite. This study demonstrates that multielemental stream-sediment analyses can be used to infer the provenance of stream sediments. Such data are available for many parts of the country as a result of the National Uranium Resource Evaluation. This study suggests that stream-sediment samples collected in the Rocky Mountains can be used either as pathfinders or as direct indicators to select targets for mineral exploration for a host of metals

  1. The scientific measurement and evaluation programme (WMEP). Annual evaluation 1996; Wissenschaftliches Mess- und Evaluierungsprogramm (WMEP) zum Breitentest '250 MW Wind'. Jahresauswertung 1996

    Energy Technology Data Exchange (ETDEWEB)

    Durstewitz, M.; Ensslin, C.; Hahn, B.; Hoppe-Klipper, M. (comps.)

    1997-07-01

    The Bundesministerium fuer Bildung, Wissenschaft, Forschung und Technik (B.M.B.F.-Federal Ministry for Education, Science, Research and Technology) funds the '250 MW Wind' test programme. This programme is designed to acquire statistically relevant data concerning the practical use of wind energy converters (WECs) in the Federal Republic of Germany. The technological and scientific areas of this supportive measure, the 'Wissenschaftliche Mess- und Evaluierungsprogramm' (WMEP - Scientific Measurement and Evaluation Programme), are implemented by the Institut fuer Solare Energieversorgungstechnik (ISET - Institute for Solar Energy Supply Technology) in Kassel. The WMEP acquires and evaluates performance data concerning all funded WECs for a 10 year period. The following areas are the main focal points of the programme: Wind Resources: Local and regional distribution of wind resources in Germany, wind conditions at specific sites. WEC Performance: Energy production and consumption of WECs, periods of grid interconnection, periods of full and partial load, performance characteristics. Reliability: Technical availability, causes of faults, malperformance, component failure. Economics: Income through the operation of the WEC, costs related to maintenance, repair and insurance. Intensive statistical evaluations concerning these focal points are implemented, based on the continuously acquired operational data of each WEC. The results are presented in this report, in a form compatible to the evaluations of recent years. (orig.)

  2. Redox behaviour of vanadium during hydrogen-oxygen exposure of the V2O5-WO3/TiO2 SCR catalyst at 250 degrees C

    DEFF Research Database (Denmark)

    Due-Hansen, Johannes; Rasmussen, Søren B.; Mikolajska, Ewelina;

    2011-01-01

    A series of experiments was conducted to reveal the impact on the catalyst and NH3-SCR activity of an industrial deNO(x) catalyst from Haldor Topsee A/S (V2O5-WO3/TiO2) by exposure to H-2 and H-2/O-2. Treatment of the SCR catalyst was done by exposure for 60min with three different concentrations...... of H-2 (0-2%) in an 8% O-2/N-2 mixture, where the SCR activity was measured before and after the hydrogen treatment. The results show that the activity of the SCR catalyst is only negligibly affected during exposure to the H-2/O-2 gas and in all cases it returned reversibly to the initial NOx...... conversion rate after reexposure to the standard NH3-SCR gas. In situ electron paramagnetic resonance (EPR) and UV-vis spectroscopy at 250 degrees C suggest that a significant part of V4+ present during SCR conditions was oxidized to V5+ during exposure to 2% H-2 + 8% O-2. However, the distribution...

  3. Vapour liquid equilibria of monocaprylin plus palmitic acid or methyl stearate at P=(1.20 and 2.50) kPa by using DSC technique

    DEFF Research Database (Denmark)

    Cunico, Larissa P.; Damaceno, Daniela S.; Matricarde Falleiro, Rafael M.;

    2015-01-01

    The Differential Scanning Calorimetry (DSC) technique is used for measuring isobaric (vapour+liquid) equilibria for two binary mixtures: {monocaprylin+palmitic acid (system 1) or methyl stearate (system 2)} at two different pressures P=(1.20 and 2.50) kPa. The obtained PTx data are correlated by ...

  4. Response of pteropods and foraminifera to changing pCO2 and pH in last 250,000 years

    Science.gov (United States)

    Hart, Malcolm; Wall-Palmer, Deborah; Smart, Christopher

    2010-05-01

    Over the last 250,000 years the diversity and quality of preservation of pteropods (holoplanktic gastropods) has fluctuated in response to glacial/interglacial cycles. This is almost certainly related to the change in oceanic pH as the best preservation is recorded in glacial cycles when pCO2 was at a lower level than during interglacials. Detailed studies of the pteropod assemblages from marine cores taken near Montserrat (Caribbean Sea) have provided a high resolution database with which to make comparisons world-wide. There are peaks of diversity (and good preservation) in Marine Isotope Stages 2 and 6 and these can be found elsewhere in the Gulf of Mexico, in the Indian Ocean and the South China Sea. Using a "pteropod preservation index" it can be seen that this parallels the changing pCO2 and pH and is clearly related. Research on benthic foraminifera living in high CO2, low pH waters near Ischia (Bay of Naples) shows that it is possible to change the foraminifera living in the environment with a change of pH from 8.14 to 7.8 and 7.6. The changes in the diversity and composition of the foraminiferal assemblages parallel changes seen in other benthic faunas (e.g., gastropods, bivalves, echinoderms and calcareous algae). The reductiuon in foraminiferal diversity and the change in the composition of the assemblage is seen to be triggered by a very small change in pH, and something which - if present trends continue - could be seen in the natural world in a few decades.

  5. Saving Salmon Through Advances in Fluvial Remote Sensing: Applying the Optimal Band Ratio Analysis (OBRA) for Bathymetric Mapping of Over 250 km of River Channel and Habitat Classification

    Science.gov (United States)

    Richardson, R.; Legleiter, C. J.; Harrison, L.

    2015-12-01

    Salmonids are threatened with extinction across the world from the fragmentation of riverine ecosystems from dams and diversions. In California, efforts to expand the range of spawnable habitat for native salmon by transporting fish around reservoirs is a potentially species saving idea. But, strong scientific evidence of the amount of high quality habitat is required to make these difficult management decisions. Remote sensing has long been used in fluvial settings to identify physical parameters that drive the quality of aquatic habitat; however, the true strength of remote sensing to cover large spatial extents has not been applied with the resolution that is relevant to salmonids. This project utilizes hyperspectral data of over 250 km of the Tuolumne and Merced Rivers to extract depth and bed slope from the wetted channel and NIR LiDAR for the surrounding topography. The Optimal Band Ratio Analysis (OBRA) has proven as an effective tool to create bathymetric maps of river channels in ideal settings with clear water, high amounts of bottom reflectance, and less than 3 meters deep over short distances. Results from this study show that OBRA can be applied over larger riverscapes at high resolutions (0.5 m). The depth and bed slope estimations are used to classify habitat units that are crucial to quantifying the quality and amount of habitat in these river that once produced large populations of native salmonids. As more managers look to expand habitat for these threatened species the tools developed here will be cost effective over the large extents that salmon migrate to spawn.

  6. New (p, {rho}, T) data for carbon dioxide - Nitrogen mixtures from (250 to 400) K at pressures up to 20 MPa

    Energy Technology Data Exchange (ETDEWEB)

    Mondejar, M.E.; Martin, M.C. [Grupo de Termodinamica y Calibracion (TERMOCAL), Dpto. Ingenieria Energetica y Fluidomecanica, Escuela de Ingenierias Industriales, Universidad de Valladolid, Paseo del Cauce, 59, E-47011 Valladolid (Spain); Span, R. [Lehrstuhl fuer Thermodynamik, Fakultaet fuer Maschinenbau Gebaeude IB, Ebene 5, Ruhr-Universitaet Bochum, Universitaetsstr. 150, 44780 Bochum (Germany); Chamorro, C.R., E-mail: cescha@eis.uva.es [Grupo de Termodinamica y Calibracion (TERMOCAL), Dpto. Ingenieria Energetica y Fluidomecanica, Escuela de Ingenierias Industriales, Universidad de Valladolid, Paseo del Cauce, 59, E-47011 Valladolid (Spain)

    2011-12-15

    Highlights: > Densities of two mixtures of nitrogen and carbon dioxide are reported. > Experimental data are compared with calculated densities from the equation of state. > Experimental data agree with the equation of state for low pressures above 300 K. > The equation of state shows higher deviations than expected at high pressures. - Abstract: Comprehensive (p, {rho}, T) measurements on two binary mixtures (0.10 CO{sub 2} + 0.90 N{sub 2} and 0.15 CO{sub 2} + 0.85 N{sub 2}) were carried out in the gas phase at seven isotherms between (250 and 400) K and pressures up to 20 MPa using a single sinker densimeter with magnetic suspension coupling. A total of 69 (p, {rho}, T) data for the first mixture and 69 (p, {rho}, T) data for the second are presented in this article. The uncertainty in density was estimated to be (0.02 to 0.15)%, while the uncertainty in temperature was 3.9 mK and the uncertainty in pressure was less than 0.015% (coverage factor k = 2). Experimental results were compared with densities calculated from the GERG equation of state and with data reported by other authors for similar mixtures. Results yielded that, while deviations between experimental data and values calculated from the GERG equation were lower than 0.05% in density for low pressures, the relative error at high pressures and low temperatures increased to about (0.2 to 0.3)%. The main aim of this work was to contribute to an accurate density data base for CO{sub 2}/N{sub 2} mixtures and to check or improve equations of state existing for these binary mixtures.

  7. Study of instability formation and EUV emission in thin liners driven with a compact 250 kA, 150 ns linear transformer driver

    Energy Technology Data Exchange (ETDEWEB)

    Valenzuela, J. C., E-mail: jcval@ucsd.edu; Collins, G. W.; Mariscal, D.; Beg, F. N. [Center for Energy Research, University of California San Diego, La Jolla, California 92093 (United States); Wyndham, E. S. [Facultad de Física, Pontificia Universidad Católica de Chile, Ave. Vicuña Mackena 4860, Macul, Santiago (Chile)

    2014-03-15

    A compact linear transformer driver, capable of producing 250 kA in 150 ns, was used to study instability formation on the surface of thin liners. In the experiments, two different materials, Cu and Ni, were used to study the effect of the liner's resistivity on formation and evolution of the instabilities. The dimensions of the liners used were 7 mm height, 1 mm radius, and 3 μm thickness. Laser probing and time resolved extreme ultraviolet (EUV) imaging were implemented to diagnose instability formation and growth. Time-integrated EUV spectroscopy was used to study plasma temperature and density. A constant expansion rate for the liners was observed, with similar values for both materials. Noticeable differences were found between the Cu and Ni instability growth rates. The most significant perturbation in Cu rapidly grows and saturates reaching a limiting wavelength of the order of the liner radius, while the most significant wavelength in Ni increases slowly before saturating, also at a wavelength close to the liner radius. Evidence suggests that the instability observed is the well-known m = 0 MHD instability. However, upon comparing the instability evolution of Cu and Ni, the importance of the resistivity on the seeding mechanism becomes evident. A comparison of end-on and side-on EUV emission possible indicates the formation of precursor plasma, where it has been estimated using EUV spectroscopy that the precursor plasma temperature is approximately 40 eV with ion density of order 10{sup 19} cm{sup −3}, for both materials.

  8. Comparison of Clinical and Laboratory Responses in Sheep and Dogs following Whole-Body Exposures to 250-Kvp X-Rays and Fission-Spectrum Neutrons

    International Nuclear Information System (INIS)

    Fifteen sheep and eight dogs were exposed to 400 rad (air dose) of pulsed fission-spectrum neutrons, and an equal number of sheep and 14 dogs to 400 r (midline air dose) 250 kVp X-rays. Seven additional sheep and four dogs served as un-irradiated controls. Control data were obtained for two weeks preceding the exposures and at frequent and regular intervals after the injury. In sheep, the most consistent clinical change was complete loss of wool by the 51st day post-exposure. The underlying skin was pink in colour closely resembling that of a mild blush sometimes noted in humans. Dogs did not demonstrate loss of hair. Formed blood elements, neutrophils, lymphocytes, and thrombocytes fell rapidly after the radiation in both species. At about post-exposure day 24 recovery in white cell numbers was noted only in the neutron groups. Thrombocyte levels decreased to safe level in both species but somewhat earlier in the dog. Recovery appeared during the third post-exposure week in both species ex posed to neutrons, but not in those given X-rays. Red blood-cell haematocrits showed significant drops in both groups of dogs by the ninth day, but neither group of sheep exhibited significant decrease in haematocrit values. Plasma Fe59 clearance rates were determined in the experimental subjects as a parameter of measurement of haematopoietic function. Prognostic implications of alteration in this parameter of haemapoiesis are discussed. The most significant gross-pathologic changes were confined to the lungs wherein extensive perivascular haemorrhage around the arteries was noted. On microscopic study the area of haemorrhage was observed to be within the advential-connective tissue and periarterial vessels. Thirty-day mortality for dogs was 50% following neutron exposures and 93% after the X-ray insult. In sheep neutrons produced 22% mortality and X-rays 80%. (author)

  9. Change of Cr atoms distribution in Fe85Cr15 alloy caused by 250 keV He+ ion irradiation to different doses

    International Nuclear Information System (INIS)

    Highlights: • Effect of He-ion irradiation dose on Fe85Cr15 alloy. • Irradiation-induced clustering of Cr atoms. • Irradiation-caused reorientation of the surface magnetization vector. • Irradiation-caused increase of Fe-site spin-density. - Abstract: Redistribution of Cr atoms in a Fe85Cr15 alloy caused by its irradiation with 250 keV He+ ions to different doses, D = 8 ⋅ 1016, 16 ⋅ 1016 and 48 ⋅ 1016 ions/cm2 was investigated by means of conversion electrons Mössbauer spectroscopy. The redistribution was expressed in terms of the Warren–Cowley short-range order parameters α1, α2 and α12 pertaining to the first (1NN), second (2NN) and both i.e. 1NN + 2NN shells, respectively. Clear evidence was found, both for non-irradiated and irradiated samples that the actual distribution of Cr atoms is characteristic of the shell, and for a given shell it depends on the irradiation dose. In particular, α1 is positive, hence indicates an under population of Cr atoms in 1NN with respect to the random case, α2 is negative, giving evidence thereby that 2NN is overpopulated by Cr atoms, and α12 is weakly positive. Under the applied irradiation the number of Cr atoms in both neighbor shells decreased signifying thereby a clustering of Cr atoms. The underlying decrease of Cr concentration within the 1NN–2NN volume around the probe Fe atoms was estimated at 1.5 at.% ranging between 2.1 for the lowest and 0.8 at.% for the highest dose

  10. Evaluation of the menisci of the knee joint using three-dimensional isotropic resolution fast spin-echo imaging: diagnostic performance in 250 patients with surgical correlation

    International Nuclear Information System (INIS)

    To compare the diagnostic performance of FSE-Cube, a three-dimensional isotropic resolution intermediate-weighted fast spin-echo sequence, with a routine magnetic resonance (MR) protocol at 3.0 T for detecting surgically confirmed meniscal tears of the knee joint in a large patient population. FSE-Cube was added to a routine MR protocol performed at 3.0 T on 250 patients who underwent subsequent knee arthroscopy. Three radiologists independently used FSE-Cube during one review and the routine MR protocol during a second review to detect medial and lateral meniscal tears. Using arthroscopy as the reference standard, the sensitivity and specificity of FSE-Cube and the routine MR protocol for detecting meniscal tears were determined for all readers combined. McNemar's tests were used to compare diagnostic performance between FSE-Cube and the routine MR protocol. FSE-cube and the routine MR protocol had similar sensitivity (95.5%/95.3% respectively, P=0.94) and similar specificity (69.8%/74.0% respectively, P=0.10) for detecting 156 medial meniscal tears. FSE-Cube had significantly lower sensitivity than the routine MR protocol (79.4%/85.0% respectively, P < 0.05) but similar specificity (83.9%/82.2% respectively, P=0.37) for detecting 89 lateral mensical tears. For lateral meniscal tears, FSE-Cube had significantly lower sensitivity (P < 0.05) than the routine MR protocol for detecting 19 root tears but similar sensitivity (P=0.17-1.00) for detecting all other tear locations and types. FSE-Cube had diagnostic performance similar to a routine MR protocol for detecting meniscal tears except for a significantly lower sensitivity for detecting lateral meniscal tears, which was mainly attributed to decreased ability to identify lateral meniscus root tears. (orig.)

  11. Surface complexation of neodymium at the rutile-water interface: A potentiometric and modeling study in NaCl media to 250°C

    Science.gov (United States)

    Ridley, Moira K.; Machesky, Michael L.; Wesolowski, David J.; Palmer, Donald A.

    2005-01-01

    The adsorption of Nd 3+ onto rutile surfaces was examined by potentiometric titration from 25 to 250°C, in 0.03 and 0.30 m NaCl background electrolyte. Experimental results show that Nd 3+ sorbs strongly, even at low temperature, with adsorption commencing below the pH znpc of rutile. In addition, there is a systematic increase in Nd 3+ adsorption with increasing temperature. The experimental results were rationalized and described using surface oxygen proton affinities computed from the MUlti SIte Complexation or MUSIC model, coupled with a Stern-based three-layer description of the oxide/water interface. Moreover, molecular-scale information was incorporated successfully into the surface complexation model, providing a unique geometry for the adsorption of Nd 3+ on rutile. The primary mode of Nd 3+ adsorption was assumed to be the tetradentate configuration found for Y 3+ adsorption on the rutile (110) surface from previously described in situ X-ray standing wave experiments, wherein the sorbing cations bond directly with two adjacent "terminal" and two adjacent "bridging" surface oxygen atoms. Similarly, the adsorption of Na + counterions was also assumed to be tetradentate, as supported by MD simulations of Na + interactions with the rutile (110) surface, and by analogous X-ray standing wave results for Rb + adsorption on rutile. Fitting parameters for Nd 3+ adsorption included binding constants for the tetradentate adsorption complex and capacitance values for the inner-sphere binding plane. In addition, hydrolysis of the tetradentate adsorption complex was permitted and resulted in significantly improved model fits at higher temperature and pH values. The modeling results indicate that the Stern-based MUSIC surface-complexation model adequately accommodates molecular-scale information to uniquely rationalize and describe multivalent ion adsorption systematically into the hydrothermal regime.

  12. Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.

    Directory of Open Access Journals (Sweden)

    I-Ting Chow

    Full Text Available Susceptibility to type 1 diabetes (T1D is strongly associated with MHC class II molecules, particularly HLA-DQ8 (DQ8: DQA1*03:01/DQB1*03:02. Monitoring T1D-specific T cell responses to DQ8-restricted epitopes may be key to understanding the immunopathology of the disease. In this study, we examined DQ8-restricted T cell responses to glutamic acid decarboxylase 65 (GAD65 using DQ8 tetramers. We demonstrated that GAD65 121-140 and GAD65 250-266 elicited responses from DQ8+ subjects. Circulating CD4+ T cells specific for these epitopes were detected significantly more often in T1D patients than in healthy individuals after in vitro expansion. T cell clones specific for GAD65 121-140 and GAD65 250-266 carried a Th1-dominant phenotype, with some of the GAD65 121-140-specific T cell clones producing IL-17. GAD65 250-266-specific CD4+ T cells could also be detected by direct ex vivo staining. Analysis of unmanipulated peripheral blood mononuclear cells (PBMCs revealed that GAD65 250-266-specific T cells could be found in both healthy and diabetic individuals but the frequencies of specific T cells were higher in subjects with type 1 diabetes. Taken together, our results suggest a proinflammatory role for T cells specific for DQ8-restricted GAD65 121-140 and GAD65 250-266 epitopes and implicate their possible contribution to the progression of T1D.

  13. Cost-effectiveness of combination fluticasone propionate–salmeterol 250/50 μg versus salmeterol in severe COPD patients

    Directory of Open Access Journals (Sweden)

    An

    2010-06-01

    Full Text Available Anand A Dalal1, Meaghan St Charles2, Hans V Petersen2, Melissa H Roberts2, Christopher M Blanchette2, Kathy Manavi-Zieverink31US Health Outcomes, GlaxoSmithKline, Research Triangle Park, NC, 2Division of Clinical and Outcomes Research, Lovelace Respiratory Research Institute, Kannapolis USA; 3INC Research, Raleigh; NC, USAObjective: To estimate the cost-effectiveness of fluticasone propionate–salmeterol combination (FSC compared to salmeterol for maintenance therapy in severe chronic obstructive pulmonary disease (COPD.Study design: Pooled economic analysis.Methods: We performed an economic analysis of pooled data from two randomized clinical trials (combined N = 1554 that evaluated the effect of maintenance therapy with FSC (250/50 μg twice daily or salmeterol (50 μg twice daily on exacerbation rates in patients with severe COPD. We calculated exacerbation rates and applied standardized costs to exacerbation-related health care utilization reported in the trials (office, urgent care, and emergency department visits; hospitalizations; and oral corticosteroids and antibiotics to determine cost differences between FSC and salmeterol treatment outcomes.Results: Annual rates of any exacerbation and moderate/severe exacerbation were lower in the FSC group than the salmeterol group (4.91 vs 5.78 and 1.32 vs 2.00 respectively, both P < 0.05. Total adjusted annual COPD related exacerbation and therapeutic costs were $4,842 (95% CI; $4,731–$4,952 in the FSC group and $5,066 (95% CI; $4,937–$5,195 in the salmeterol group.Conclusions: FSC combination therapy is associated with reduced risk of any exacerbation and moderate/severe exacerbation, and incurs lower annual COPD-related health care costs compared to treatment with salmeterol. This analysis demonstrates that FSC therapy may be advantageous from both a clinical and cost-benefit standpoint for patients with severe COPD.Keywords: COPD, cost-effectiveness analysis, economic, maintenance therapy

  14. Hypothesis of homeothermy evolution on isolated South China Craton that moved from equator to cold north latitudes 250-200Myr ago.

    Science.gov (United States)

    Kurbel, Sven

    2014-01-01

    Based on avian and mammalian fossils found in the northeastern Chinese province of Liaoning and physiological traits linked to homeothermy, a hypothesis of evolution of homeothermic animals is proposed. It is based on the importance of muscle function in cold environment, as a strong selection pressure that favors endothermic metabolism during periods of cold climates. The presented hypothesis postulates that in progressively cooling environment, animals will develop thermal insulation, increased basal metabolism if food is available, and torpor when food is scarce. Since late Permian, Triassic and Cretaceous global temperatures were high, an exceptional place that gradually became cold was needed for the homeothermy evolution. South China Craton is here proposed as a plausible candidate for that role since it drifted across the Paleo-Tethys ocean, from equator to high northern latitudes in a journey that lasted from 250 to 200Myr ago. After this small continent collided with North China Craton some 200Myr ago, the already cold-adapted animals had spread to large, mostly empty spaces on the North China Craton, due to their evolutionary advantage of making active living in the cold environment. The most advantageous early homeothermic animals went further north to the cold Liaoning to start an oasis that delivered modern birds during next 50Myr. Modern mammals possibly evolved somewhere in the cold vicinity. This made Liaoning and similarly cold places the cradles of early birds and early mammals since for the following millions of years these places remained too cold for poikilotherms to enter and warm enough for homeotherms to dwell, until the Cretaceous-Paleogene extinction event and subsequent global cooling that diminished poikilotherms. Homeothermy was probably even more important as a survival advantage in cooler climates of Paleogene, when mammals and birds became dominant animals. This interpretation is probably supported by a recent report that a small

  15. Study of solar features causing GMSs with 250c'gamma' 'smaller than' H 'smaller than' 400'gamma' during the period 1999-2010

    Science.gov (United States)

    Kumar, Rajiv

    2016-07-01

    The effect of solar features on geospheric conditions leading to geomagnetic storms (GMSs) with planetary index,A P ≥ 20 and the range of horizontal component of the Earth's magnetic field H such that 250γ data (SGD) during the period 1999-2010. Statistically, it is observed that maximum number of GMSs have occurred during the maximum solar activity years of 23rd and 24th solar cycles. A peculiar result has been observed during the years 2000, 2002 when sunspot numbers (SSNs) decrease very rapidly while numbers of GMSs increase. No distinct association between yearly occurrence of disturbed days and SSNs is observed. Maximum number of disturbed days have occurred during spring and rainy seasons showing a seasonal variation of disturbed days. No significant correlation between magnitude (intensity) of GMSs and importance ofH α , X-ray solar flares has been observed. Maximum number of GMSs is associated with solar flares of lower importance, i.e., SF during the period 1978-93.H α , X-ray solar flares occurred within lower helio-latitudes, i.e., (0-30)°N to (0-30)°S are associated with GMSs. NoH α , X-ray solar flares have occurred beyond 40°N or 40°S in association with GMSs. In helio-latitude range (10-40)°N to (10-40)°S, the 89.5% concentration of active prominences and disappearing filaments (APDFs) are associated with GMSs. Maximum number of GMSs are associated with solar flares. Coronal mass ejections (CMEs) are related with eruptive prominences, solar flares, type IV radio burst and they occur at low helio-latitude. It is observed that CMEs related GMS events are not always associated with high speed solar wind streams (HSSWSs). In many individual events, the travel time between the explosion on the Sun and maximum activity lies between 58 and 118 h causing GMSs at the Earth. Keywords Geomagnetic storm solar flares active prominences and disappearing filaments coronal mass ejections helio-latitude helio-longitude sunspot numbers

  16. A Novel approach to monitor chlorophyll-a concentration using an adaptive model from MODIS data at 250 metres spatial resolution

    Science.gov (United States)

    El Alem, A.; Chokmani, K.; Laurion, I.; El Adlouni, S.

    2013-12-01

    Occurrence and extent of Harmful Algal Bloom (HAB) has increased in inland water bodies around the world. The appearance of these blooms reflects the advanced state of eutrophication of several aquatic systems caused by urban, agricultural, and industrial development. Algal blooms, especially those cyanobacterial origins, are capable to produce and release toxins, threatening human and animal health, quality of drinking water, and recreational water bodies. Conventional monitoring networks, based on infrequent sampling in a few fixed monitoring stations, cannot provide the information needed as HABs are spatially and temporally heterogeneous. Remote sensing represents an interesting alternative to provide the required spatial and temporal coverage. The usefulness of air-borne and satellite remote sensing data to detect HABs was demonstrated since three decades ago, and since several empirical and semi-empirical models, using satellite imagery, were developed to estimate chlorophyll-a concentration [Chl-a] as a proxy to detect bloom proliferations. However, most of those models presented several weaknesses that are generally linked to the range of [Chl-a] to be estimated. Indeed, models originally calibrated for high [Chl-a] fail to estimate low concentrations and vice versa. In this study, an adaptive model to estimate [Chl-a], spread over a wide range of concentrations, is developed for optically complex inland water bodies based on combination of water spectral response classification and three developed semi-empirical algorithms using a multivariate regression. Three distinct water types (low, medium, and high [Chl-a]) are first identified using the Classification and Regression Tree (CART) method performed on remote sensing reflectance over a dataset of 44 [Chl-a] samples collected from Lakes over Quebec province. Based on the water classification, a specific multivariate model to each water type is developed using the same dataset and the MODIS data at 250-m

  17. A Novel approach for monitoring cyanobacterial blooms using an ensemble based system from MODIS imagery downscaled to 250 metres spatial resolution

    Science.gov (United States)

    El Alem, A.; Chokmani, K.; Laurion, I.; El-Adlouni, S. E.

    2014-12-01

    In reason of inland freshwaters sensitivity to Harmful algae blooms (HAB) development and the limits coverage of standards monitoring programs, remote sensing data have become increasingly used for monitoring HAB extension. Usually, HAB monitoring using remote sensing data is based on empirical and semi-empirical models. Development of such models requires a great number of continuous in situ measurements to reach an acceptable accuracy. However, Ministries and water management organizations often use two thresholds, established by the World Health Organization, to determine water quality. Consequently, the available data are ordinal «semi-qualitative» and they are mostly unexploited. Use of such databases with remote sensing data and statistical classification algorithms can produce hazard management maps linked to the presence of cyanobacteria. Unlike standard classification algorithms, which are generally unstable, classifiers based on ensemble systems are more general and stable. In the present study, an ensemble based classifier was developed and compared to a standard classification method called CART (Classification and Regression Tree) in a context of HAB monitoring in freshwaters using MODIS images downscaled to 250 spatial resolution and ordinal in situ data. Calibration and validation data on cyanobacteria densities were collected by the Ministère du Développement durable, de l'Environnement et de la Lutte contre les changements climatiques on 22 waters bodies between 2000 and 2010. These data comprise three density classes: waters poorly ( 100,000 cells mL-1) loaded in cyanobacteria. Results were very interesting and highlighted that inland waters exhibit different spectral response allowing them to be classified into the three above classes for water quality monitoring. On the other, even if the accuracy (Kappa-index = 0.86) of the proposed approach is relatively lower than that of the CART algorithm (Kappa-index = 0.87), but its robustness is

  18. Using MODIS True-Color 250 m Remote Sensing Data to Assess Interannual Variability of Suspended Matter over Southeastern Brazilian Continental Shelf

    Science.gov (United States)

    Belem, A. L.; Silva, T. M. L.; Albuquerque, A. L.

    2014-12-01

    Continental shelf is the final destination of terrigenous sediments drained by rivers and estuaries, forming a mass of water drifting over the shelf due to its differential density from underlaying salty oceanic waters, forming a coastal plume. On the Southeastern Brazilian Continental Shelf, Cabo Frio region represents the limit between Santos and Campos basin oil reserves. The continental drainage in this area is not expressive, nevertheless presents a complex interaction between the western boundary Brazil Current (BC) and shelf border mechanisms providing amid-shelf intrusion and a coastal upwelling of South Atlantic Central Water (SACW) over the shelf. Satellite images of the region shows expressive shelf plumes with sedimentary contributions from Paraiba do Sul river located approximately 180 km northward of Cabo Frio, as well as from Guanabara bay, located 150 km westward of Cabo Frio. In order to understand the role of plumes in sedimentary processes over the continental shelf, this study analyzed 10 years of MODIS true-color 250 m remote sensing data in order to understand the temporal variability of the shelf front and the area of plumes. The remote data were obtained from the Aerosol Robotic Network and USDA Foreign Agricultural Service subsets. Selected 17% of daily images were cloud-free to allow shelf plumes to be delimited and processed to enhancement of features as well as land masking, geo-referencing, and daily area calculation on pixel basis. During austral winter (dry season) the plumes get its maximum extension in area over the shelf, suggesting that the mechanism of sediment transport is connected with high energetic wave-wind interactions on the coast followed by wind-driven dispersion less than continental drainage. The interannual pattern shows a general decreasing trend, mainly in the last 4 years, associated with sediment availability on the inner shelf, which is driven by river discharge during the austral summer (rain season). We also

  19. Study of solar features causing GMSs with 250c'gamma' 'smaller than' H 'smaller than' 400'gamma' during the period 1999-2010

    Science.gov (United States)

    Kumar, Rajiv

    2016-07-01

    The effect of solar features on geospheric conditions leading to geomagnetic storms (GMSs) with planetary index,A P ≥ 20 and the range of horizontal component of the Earth's magnetic field H such that 250γ activity years of 23rd and 24th solar cycles. A peculiar result has been observed during the years 2000, 2002 when sunspot numbers (SSNs) decrease very rapidly while numbers of GMSs increase. No distinct association between yearly occurrence of disturbed days and SSNs is observed. Maximum number of disturbed days have occurred during spring and rainy seasons showing a seasonal variation of disturbed days. No significant correlation between magnitude (intensity) of GMSs and importance ofH α , X-ray solar flares has been observed. Maximum number of GMSs is associated with solar flares of lower importance, i.e., SF during the period 1978-93.H α , X-ray solar flares occurred within lower helio-latitudes, i.e., (0-30)°N to (0-30)°S are associated with GMSs. NoH α , X-ray solar flares have occurred beyond 40°N or 40°S in association with GMSs. In helio-latitude range (10-40)°N to (10-40)°S, the 89.5% concentration of active prominences and disappearing filaments (APDFs) are associated with GMSs. Maximum number of GMSs are associated with solar flares. Coronal mass ejections (CMEs) are related with eruptive prominences, solar flares, type IV radio burst and they occur at low helio-latitude. It is observed that CMEs related GMS events are not always associated with high speed solar wind streams (HSSWSs). In many individual events, the travel time between the explosion on the Sun and maximum activity lies between 58 and 118 h causing GMSs at the Earth. Keywords Geomagnetic storm solar flares active prominences and disappearing filaments coronal mass ejections helio-latitude helio-longitude sunspot numbers

  20. The Behavior of IAPWS-95 from 250 to 300 K and Pressures up to 400 MPa: Evaluation Based on Recently Derived Property Data

    Science.gov (United States)

    Wagner, Wolfgang; Thol, Monika

    2015-12-01

    Over the past several years, considerable scientific and technical interest has been focused on accurate thermodynamic properties of fluid water covering part of the subcooled (metastable) region and the stable liquid from the melting line up to about 300 K and pressures up to several hundred MPa. Between 2000 and 2010, experimental density data were published whose accuracy was not completely clear. The scientific standard equation of state for fluid water, the IAPWS-95 formulation, was developed on the basis of experimental data for thermodynamic properties that were available by 1995. In this work, it is examined how IAPWS-95 behaves with respect to the experimental data published after 1995. This investigation is carried out for temperatures from 250 to 300 K and pressures up to 400 MPa. The starting point is the assessment of the current data situation. This was mainly performed on the basis of data for the density, expansivity, compressibility, and isobaric heat capacity, which were derived in 2015 from very accurate speed-of-sound data. Apart from experimental data and these derived data, property values calculated from the recently published equation of state for this region of Holten et al. (2014) were also used. As a result, the unclear data situation could be clarified, and uncertainty values could be estimated for the investigated properties. In the region described above, detailed comparisons show that IAPWS-95 is able to represent the latest experimental data for the density, expansivity, compressibility, speed of sound, and isobaric heat capacity to within the uncertainties given in the release on IAPWS-95. Since the release does not contain uncertainty estimates for expansivities and compressibilities, the statement relates to the error propagation of the given uncertainty in density. Due to the lack of experimental data for the isobaric heat capacity for pressures above 100 MPa, no uncertainty estimates are given in the release for this pressure