WorldWideScience

Sample records for berkelium 249

  1. 46 CFR 169.249 - Pressure vessels.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Pressure vessels. 169.249 Section 169.249 Shipping COAST... and Certification Inspections § 169.249 Pressure vessels. Pressure vessels must meet the requirements of part 54 of this chapter. The inspection procedures for pressure vessels are contained in...

  2. 32 CFR 249.6 - Responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 249.6 Section 249.6 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PRESENTATION OF DoD-RELATED SCIENTIFIC AND TECHNICAL PAPERS AT MEETINGS § 249.6 Responsibilities. (a) The...

  3. 14 CFR 249.4 - Photographic copies.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Photographic copies. 249.4 Section 249.4 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS PRESERVATION OF AIR CARRIER RECORDS General Instructions § 249.4 Photographic copies. (a)...

  4. 7 CFR 249.3 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 249.3 Section 249.3 Agriculture... CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) General § 249.3 Administration. (a) Delegation to FNS. Within FNS, FNS shall act on behalf of the Department in the administration...

  5. 49 CFR 234.249 - Ground tests.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Ground tests. 234.249 Section 234.249 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION..., Inspection, and Testing Inspections and Tests § 234.249 Ground tests. A test for grounds on each energy...

  6. 46 CFR 249.6 - Application procedures.

    Science.gov (United States)

    2010-10-01

    ... OPERATORS APPROVAL OF UNDERWRITERS FOR MARINE HULL INSURANCE § 249.6 Application procedures. (a) MARAD may grant specific approval for underwriters described in § 249.5(c) to participate in the writing of marine... submissions are considered inadequate; (2) A comprehensive description and English language version of...

  7. 48 CFR 5452.249 - Allocation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Allocation. 5452.249... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 5452.249 Allocation. The Defense... contemplated and the contract amount is expected to exceed the small purchase limitation. Allocation (DFSC...

  8. 7 CFR 249.9 - Nutrition education.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nutrition education. 249.9 Section 249.9 Agriculture... Nutrition education. (a) Goal. Nutrition education shall emphasize the relationship of proper nutrition to... agency shall integrate nutrition education into SFMNP operations and may satisfy nutrition...

  9. 7 CFR 249.4 - State Plan.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) State Agency Eligibility § 249..., and/or nutrition education, as required in § 249.3(d). (2) A description of the State...

  10. 7 CFR 249.26 - SFMNP information.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false SFMNP information. 249.26 Section 249.26 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions §...

  11. 7 CFR 249.13 - Program income.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Program income. 249.13 Section 249.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) State Agency Provisions §...

  12. 7 CFR 249.18 - Audits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Audits. 249.18 Section 249.18 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Monitoring and Review of...

  13. 7 CFR 249.15 - Closeout procedures.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Closeout procedures. 249.15 Section 249.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) State Agency Provisions §...

  14. Dicty_cDB: SLB249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLB249 (Link to dictyBase) - - - Contig-U16455-1 SLB249Z (Link... to Original site) - - SLB249Z 727 - - - - Show SLB249 Library SL (Link to library) Clone ID SLB249 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLB2-C/SLB249Q.Seq.d/ Representative seq. ID SLB24...9Z (Link to Original site) Representative DNA sequence >SLB249 (SLB249Q) /CSM/SL/SLB2-C/SLB249Q.Seq.d/ XXXXX...NA Score E Sequences producing significant alignments: (bits) Value SLB249 (SLB249Q) /CSM/SL/SLB2-C/SLB249Q.

  15. Dicty_cDB: CHR249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHR249 (Link to dictyBase) - - - Contig-U16497-1 - (Link to Original site) - - CHR...249Z 694 - - - - Show CHR249 Library CH (Link to library) Clone ID CHR249 (Link to dicty...iol.tsukuba.ac.jp/CSM/CH/CHR2-C/CHR249Q.Seq.d/ Representative seq. ID - (Link to ...Original site) Representative DNA sequence >CHR249 (CHR249Q) /CSM/CH/CHR2-C/CHR249Q.Seq.d/ XXXXXXXXXXAAATGGT...xxixknqemfnsvvqiiihfmnkiq Frame C: ---w*yfphtn*qmfrlydl*ssfw*l*firxrlprw**myyqcl*ik**cpwcmyklns *mrcyqh**mypill**shr

  16. Dicty_cDB: VHF249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHF249 (Link to dictyBase) - - - Contig-U16260-1 - (Link to Original site) VHF...249F 617 - - - - - - Show VHF249 Library VH (Link to library) Clone ID VHF249 (Link to dicty...iol.tsukuba.ac.jp/CSM/VH/VHF2-C/VHF249Q.Seq.d/ Representative seq. ID - (Link to ...Original site) Representative DNA sequence >VHF249 (VHF249Q) /CSM/VH/VHF2-C/VHF249Q.Seq.d/ AACTCTCGAGTGCAAAA...VIAHVDHGKTTLSDSLIQRAGIIADKV SGDMRYMSCRADEQERGITIKSSSVSLHFEMPKEDKLPAGCTSHEFLINLIDSPGHVDFS SEVTAALRVTDGALVVIDC

  17. Dicty_cDB: SLE249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available oideum slug cDNA, clone SLE249. 1205 0.0 1 ( AF066071 ) Dictyostelium discoideum SP85 (pspB) gene, comple...SL (Link to library) SLE249 (Link to dictyBase) - - - Contig-U16325-1 SLE249Z (Link... to Original site) - - SLE249Z 668 - - - - Show SLE249 Library SL (Link to library) Clone ID SLE249 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLE2-C/SLE249Q.Seq.d/ Representative seq. ID SLE24...9Z (Link to Original site) Representative DNA sequence >SLE249 (SLE249Q) /CSM/SL/SLE2-C/SLE249Q.Seq.d/ XXXXX

  18. Dicty_cDB: VSI249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VS (Link to library) VSI249 (Link to dictyBase) - - - Contig-U16236-1 VSI249P (Link to Original site) VSI...249P (Link to Original site) Representative DNA sequence >VSI249 (VSI249Q) /CSM/VS/VSI2-C/VSI2...249F 178 VSI249Z 145 VSI249P 323 - - Show VSI249 Library VS (Link to library) Clone ID VSI...249 (Link to dictyBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16236-1 Original site... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/VS/VSI2-C/VSI249Q.Seq.d/ Representative seq. ID VSI

  19. Dicty_cDB: SFI249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available uence update 2001.11.22 Translated Amino Acid sequence cwptgifsnsfllyky*ihilffyil*HFIKKKKKKKIKKSXFLKKK--- ---KTKIQDKEGFHQINNVSF...SF (Link to library) SFI249 (Link to dictyBase) - - - Contig-U16560-1 SFI249P (Link to Original site) SF...I249F 144 SFI249Z 718 SFI249P 852 - - Show SFI249 Library SF (Link to library) Clone ID SF... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SF/SFI2-C/SFI249Q.Seq.d/ Representative seq. ID SF...I249P (Link to Original site) Representative DNA sequence >SFI249 (SFI249Q) /CSM/SF/SFI2-C/SFI2

  20. 7 CFR 249.25 - Other provisions.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions § 249... (7 U.S.C. 2011, et seq.) and to any other Federal or State food or nutrition assistance program....

  1. 7 CFR 249.12 - SFMNP costs.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) State Agency Provisions § 249...-up; (2) The costs associated with the provision of nutrition education that meets the requirements...

  2. 7 CFR 249.11 - Financial management system.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management system. 249.11 Section 249.11... § 249.11 Financial management system. (a) Disclosure of expenditures. The State agency must maintain a financial management system that provides accurate, current and complete disclosure of the financial...

  3. 7 CFR 58.249 - Instant nonfat dry milk.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Instant nonfat dry milk. 58.249 Section 58.249... Products Bearing Usda Official Identification § 58.249 Instant nonfat dry milk. (a) Only instant nonfat dry milk manufactured and packaged in accordance with the requirements of this part and with the...

  4. 46 CFR 249.10 - Non-discrimination policy.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Non-discrimination policy. 249.10 Section 249.10... OPERATORS APPROVAL OF UNDERWRITERS FOR MARINE HULL INSURANCE § 249.10 Non-discrimination policy. To administer effectively the policy regarding non-discrimination against U.S. insurers in other countries,...

  5. Mars at Ls 249o: Tharsis

    Science.gov (United States)

    2005-01-01

    5 July 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 249o during a previous Mars year. This month, Mars looks similar, as Ls 249o occurs in mid-July 2005. The picture shows the Tharsis face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn. Season: Northern Autumn/Southern Spring

  6. 7 CFR 249.5 - Selection of new State agencies.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Selection of new State agencies. 249.5 Section 249.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) State Agency...

  7. 7 CFR 249.27 - OMB Control Number.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false OMB Control Number. 249.27 Section 249.27 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions §...

  8. 7 CFR 249.20 - Claims and penalties.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Claims and penalties. 249.20 Section 249.20 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous...

  9. 7 CFR 249.21 - Procurement and property management.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Procurement and property management. 249.21 Section 249.21 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM...

  10. 28 CFR 2.49 - Place of revocation hearing.

    Science.gov (United States)

    2010-07-01

    ... PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.49 Place... conditions are met: (1) The parolee has not been convicted of a crime committed while under supervision;...

  11. 48 CFR 249.110 - Settlement negotiation memorandum.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Settlement negotiation... Settlement negotiation memorandum. Follow the procedures at PGI 249.110 for preparation of a settlement negotiation memorandum....

  12. 7 CFR 249.23 - Records and reports.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions § 249..., delivery receipts, equipment purchases and inventory, nutrition education, fair hearings, and civil...

  13. 75 FR 69870 - Delegation of Authority Under 18 U.S.C. 249

    Science.gov (United States)

    2010-11-16

    ... Part 0 Delegation of Authority Under 18 U.S.C. 249 AGENCY: Department of Justice. ACTION: Final rule... 18 U.S.C. 249, relating to hate crimes, to the Assistant Attorney General for the Civil Rights....S.C. 249. The Shepard-Byrd Act expressly provides that no prosecution under section 249 may...

  14. Search for heavy-ion emission in 249Cf decay

    Science.gov (United States)

    Ardisson, G.; Barci, V.; Le Du, J. F.; Trubert, D.; Bonetti, R.; Guglielmetti, A.; Gupta, R. K.

    1999-09-01

    Using phosphate glass detectors PKS-50, we have searched for possible emission of heavy clusters in the decay of 249Cf with the aim of confirming the result obtained from a recent γ ray spectrometry experiment. After a 20-day exposure to a 7.4 MBq activity 249Cf source of 37.5 cm2 PKS-50 glasses covered with polymide foils to stop fission fragments, no ions with 17=7.4×1021 s. According to calculations performed on the basis of the preformed cluster model there seems to be very little chance that such an exotic decay might be detected, at least in the next few years.

  15. 14 CFR 125.249 - Maintenance manual requirements.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Maintenance manual requirements. 125.249... Maintenance manual requirements. (a) Each certificate holder's manual required by § 125.71 of this part shall... manual shall contain a suitable system which may include a coded system that provides for the...

  16. 7 CFR 249.1 - General purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) General § 249.1 General... carry out the Senior Farmers' Market Nutrition Program (SFMNP). The purposes of the SFMNP are to:...

  17. 48 CFR 52.249-7 - Termination (Fixed-Price Architect-Engineer).

    Science.gov (United States)

    2010-10-01

    ... Architect-Engineer). 52.249-7 Section 52.249-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.249-7 Termination (Fixed-Price Architect-Engineer). As prescribed in 49.503(b), insert the following clause in solicitations and contracts for architect-engineer services when a fixed-price...

  18. 48 CFR 52.249-4 - Termination for Convenience of the Government (Services) (Short Form).

    Science.gov (United States)

    2010-10-01

    ... Convenience of the Government (Services) (Short Form). 52.249-4 Section 52.249-4 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.249-4 Termination for Convenience of the Government... convenience of the Government, limit termination settlement charges to services rendered before the date...

  19. 48 CFR 52.249-2 - Termination for Convenience of the Government (Fixed-Price).

    Science.gov (United States)

    2010-10-01

    ... Convenience of the Government (Fixed-Price). 52.249-2 Section 52.249-2 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.249-2 Termination for Convenience of the Government (Fixed-Price). As prescribed in 49.502(b)(1)(i), insert the following clause: Termination for Convenience of the...

  20. 17 CFR 249.331 - Form N-CSR, certified shareholder report.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-CSR, certified shareholder report. 249.331 Section 249.331 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Required Under Sections 13 and 15(d) of the Securities Exchange Act of 1934 § 249.331 Form N-CSR,...

  1. Mars at Ls 249o: Acidalia/Mare Erythraeum

    Science.gov (United States)

    2005-01-01

    12 July 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 249o during a previous Mars year. This month, Mars looks similar, as Ls 249o occurs in mid-July 2005. The picture shows the Acidalia/Mare Erythraeum face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn. Season: Northern Autumn/Southern Spring

  2. Mars at Ls 249o: Elysium/Mare Cimmerium

    Science.gov (United States)

    2005-01-01

    26 July 2005 This picture is a composite of Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) daily global images acquired at Ls 249o during a previous Mars year. This month, Mars looks similar, as Ls 249o occurred in mid-July 2005. The picture shows the Elysium/Mare Cimmerium face of Mars. Over the course of the month, additional faces of Mars as it appears at this time of year are being posted for MOC Picture of the Day. Ls, solar longitude, is a measure of the time of year on Mars. Mars travels 360o around the Sun in 1 Mars year. The year begins at Ls 0o, the start of northern spring and southern autumn. Season: Northern Autumn/Southern Spring

  3. New Results for Elements 115, 117, and 118 Produced in the Reactions 243Am+48Ca and 249BK/249Cf+48Ca

    Science.gov (United States)

    Utyonkov, V. K.; Oganessian, Yu. Ts.; Abdullin, F. Sh.; Alexander, C.; Binder, J.; Boll, R. A.; Dmitriev, S. N.; Ezold, J.; Felker, K.; Gostic, J. M.; Grzywacz, R. K.; Hamilton, J. H.; Henderson, R. A.; Itkis, M. G.; Miernik, K.; Miller, D.; Moody, K. J.; Polyakov, A. N.; Ramayya, A. V.; Roberto, J. B.; Ryabinin, M. A.; Rykaczewski, K. P.; Sagaidak, R. N.; Shaughnessy, D. A.; Shirokovsky, I. V.; Shumeiko, M. V.; Stoyer, M. A.; Stoyer, N. J.; Subbotin, V. G.; Sukhov, A. M.; Tsyganov, Yu. S.; Voinov, A. A.; Vostokin, G. K.

    2014-09-01

    The reactions of 243Am and 249Bk with 48Ca have been reinvestigated to provide new evidence for the discovery of elements 113, 115, and 117. Three isotopes 287-289115 were synthesized in the 243Am+48Ca reactions at five projectile energies, providing excitation functions and α-decay spectra of the produced isotopes. Decay properties of 287,288115 and of all the daughter products agree with the data of the experiment in which these nuclei were synthesized for the first time. The new 289115 events demonstrate the same decay properties as those observed for 289115 populated by a decay of 293117 produced in the 249Bk+48Ca reaction to provide cross-bombardment evidence. Results of recent experiments at the Dubna gas-filled recoil separator aimed at studying production crosssections, excitation functions, and nuclear decay properties for isotopes 293,294117 synthesized in the 249Bk+48Ca reaction at five projectile energies are presented. In addition, a single decay of 294118 was observed from the reaction with 249Cf - a result of the in-growth of 249Cf in the 249Bk target.

  4. Fusion and quasifission dynamics in the reactions $^{48}$Ca+$^{249}$Bk and $^{50}$Ti+$^{249}$Bk using TDHF

    CERN Document Server

    Umar, A S; Simenel, C

    2016-01-01

    Background: Synthesis of superheavy elements (SHE) with fusion-evaporation reactions is strongly hindered by the quasifission (QF) mechanism which prevents the formation of an equilibrated compound nucleus and which depends on the structure of the reactants. New SHE have been recently produced with doubly-magic $^{48}$Ca beams. However, SHE synthesis experiments with single-magic $^{50}$Ti beams have so far been unsuccessful. Purpose: In connection with experimental searches for $Z=117,119$ superheavy elements, we perform a theoretical study of fusion and quasifission mechanisms in $^{48}$Ca,$^{50}$Ti+$^{249}$Bk reactions in order to investigate possible differences in reaction mechanisms induced by these two projectiles. Methods: The collision dynamics and the outcome of the reactions are studied using unrestricted time-dependent Hartree-Fock (TDHF) calculations as well as the density-constrained TDHF method to extract the nucleus-nucleus potentials and the excitation energy in each fragment. Results: Nucleu...

  5. 7 CFR 249.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Science.gov (United States)

    2010-01-01

    ... workplace, and lobbying restrictions. 249.22 Section 249.22 Agriculture Regulations of the Department of.../suspension, drug-free workplace, and lobbying restrictions. The State agency must ensure compliance with the... lobbying (part 3018 of this title), where applicable....

  6. 7 CFR 249.14 - Distribution of funds to State agencies.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Distribution of funds to State agencies. 249.14 Section 249.14 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION...

  7. Narcolepsy and pregnancy: a retrospective European evaluation of 249 pregnancies.

    Science.gov (United States)

    Maurovich-Horvat, Eszter; Kemlink, David; Högl, Birgit; Frauscher, Birgit; Ehrmann, Laura; Geisler, Peter; Ettenhuber, Katharina; Mayer, Geert; Peraita-Adrados, Rosa; Calvo, Elena; Lammers, Gert Jan; Van der Heide, Astrid; Ferini-Strambi, Luigi; Plazzi, Giuseppe; Poli, Francesca; Dauvilliers, Yves; Jennum, Poul; Leonthin, Helle; Mathis, Johannes; Wierzbicka, Aleksandra; Puertas, Francisco J; Beitinger, Pierre A; Arnulf, Isabelle; Riha, Renata L; Tormášiová, Maria; Slonková, Jana; Nevšímalová, Sona; Sonka, Karel

    2013-10-01

    In a retrospective cohort study undertaken in 12 European countries, 249 female narcoleptic patients with cataplexy (n = 216) and without cataplexy (n = 33) completed a self-administrated questionnaire regarding pregnancy and childbirth. The cohort was divided further into patients whose symptoms of narcolepsy started before or during pregnancy (308 pregnancies) and those in whom the first symptoms of narcolepsy appeared after delivery (106 pregnancies). Patients with narcolepsy during pregnancy were older during their first pregnancy (P narcolepsy-cataplexy during pregnancy had impaired glucose metabolism and anaemia. Three patients experienced cataplexy during delivery. The rate of caesarean sections was higher in the narcolepsy-cataplexy group compared to the narcolepsy group (P narcolepsy in 60.1% of those with narcolepsy during pregnancy. This study reports more obstetric complications in patients with narcolepsy-cataplexy during pregnancy; however, these were not severe. This group also had a higher BMI and higher incidence of impaired glucose metabolism during pregnancy. Caesarian section was conducted more frequently in narcolepsy-cataplexy patients, despite cataplexy being a rare event during delivery. Furthermore, symptoms of narcolepsy may render care of the infant more difficult.

  8. 17 CFR 249.444 - Form SE, form for submission of paper format exhibits by electronic filers.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form SE, form for submission of paper format exhibits by electronic filers. 249.444 Section 249.444 Commodity and Securities... of 1934 § 249.444 Form SE, form for submission of paper format exhibits by electronic filers....

  9. 48 CFR 52.249-1 - Termination for Convenience of the Government (Fixed-Price) (Short Form).

    Science.gov (United States)

    2010-10-01

    ... Convenience of the Government (Fixed-Price) (Short Form). 52.249-1 Section 52.249-1 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.249-1 Termination for Convenience of the Government... Convenience of the Government (Fixed-Price) (Short Form) (APR 1984) The Contracting Officer, by written...

  10. Serine 249 phosphorylation by ATM protein kinase regulates hepatocyte nuclear factor-1α transactivation.

    Science.gov (United States)

    Zhao, Long; Chen, Hui; Zhan, Yi-Qun; Li, Chang-Yan; Ge, Chang-Hui; Zhang, Jian-Hong; Wang, Xiao-Hui; Yu, Miao; Yang, Xiao-Ming

    2014-07-01

    Hepatocyte nuclear factor-1 alpha (HNF1α) exerts important effects on gene expression in multiple tissues. Several studies have directly or indirectly supported the role of phosphorylation processes in the activity of HNF1α. However, the molecular mechanism of this phosphorylation remains largely unknown. Using microcapillary liquid chromatography MS/MS and biochemical assays, we identified a novel phosphorylation site in HNF1α at Ser249. We also found that the ATM protein kinase phosphorylated HNF1α at Ser249 in vitro in an ATM-dependent manner and that ATM inhibitor KU55933 treatment inhibited phosphorylation of HNF1α at Ser249 in vivo. Coimmunoprecipitation assays confirmed the association between HNF1α and ATM. Moreover, ATM enhanced HNF1α transcriptional activity in a dose-dependent manner, whereas the ATM kinase-inactive mutant did not. The use of KU55933 confirmed our observation. Compared with wild-type HNF1α, a mutation in Ser249 resulted in a pronounced decrease in HNF1α transactivation, whereas no dominant-negative effect was observed. The HNF1αSer249 mutant also exhibited normal nuclear localization but decreased DNA-binding activity. Accordingly, the functional studies of HNF1αSer249 mutant revealed a defect in glucose metabolism. Our results suggested that ATM regulates the activity of HNF1α by phosphorylation of serine 249, particularly in glucose metabolism, which provides valuable insights into the undiscovered mechanisms of ATM in the regulation of glucose homeostasis.

  11. 249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients

    Directory of Open Access Journals (Sweden)

    Paranaguá-Vezozzo Denise C

    2009-06-01

    Full Text Available Abstract Background Ser-249 TP53 mutation (249Ser is a molecular evidence for aflatoxin-related carcinogenesis in Hepatocellular Carcinoma (HCC and it is frequent in some African and Asian regions, but it is unusual in Western countries. HBV has been claimed to add a synergic effect on genesis of this particular mutation with aflatoxin. The aim of this study was to investigate the frequency of 249Ser mutation in HCC from patients in Brazil. Methods We studied 74 HCC formalin fixed paraffin blocks samples of patients whom underwent surgical resection in Brazil. 249Ser mutation was analyzed by RFLP and DNA sequencing. HBV DNA presence was determined by Real-Time PCR. Results 249Ser mutation was found in 21/74 (28% samples while HBV DNA was detected in 13/74 (16%. 249Ser mutation was detected in 21/74 samples by RFLP assay, of which 14 were confirmed by 249Ser mutant-specific PCR, and 12 by nucleic acid sequencing. All HCC cases with p53-249ser mutation displayed also wild-type p53 sequences. Poorly differentiated HCC was more likely to have 249Ser mutation (OR = 2.415, 95% CI = 1.001 – 5.824, p = 0.05. The mean size of 249Ser HCC tumor was 9.4 cm versus 5.5 cm on wild type HCC (p = 0.012. HBV DNA detection was not related to 249Ser mutation. Conclusion Our results indicate that 249Ser mutation is a HCC important factor of carcinogenesis in Brazil and it is associated to large and poorly differentiated tumors.

  12. Fusion and quasifission dynamics in the reactions 48Ca+249Bk and 50Ti+249Bk using a time-dependent Hartree-Fock approach

    Science.gov (United States)

    Umar, A. S.; Oberacker, V. E.; Simenel, C.

    2016-08-01

    Background: Synthesis of superheavy elements (SHEs) with fusion-evaporation reactions is strongly hindered by the quasifission (QF) mechanism which prevents the formation of an equilibrated compound nucleus and which depends on the structure of the reactants. New SHEs have been recently produced with doubly-magic 48Ca beams. However, SHE synthesis experiments with single-magic 50Ti beams have so far been unsuccessful. Purpose: In connection with experimental searches for Z =117 ,119 superheavy elements, we perform a theoretical study of fusion and quasifission mechanisms in 48Ca,50Ti+249Bk reactions in order to investigate possible differences in reaction mechanisms induced by these two projectiles. Methods: The collision dynamics and the outcome of the reactions are studied using unrestricted time-dependent Hartree-Fock (TDHF) calculations as well as the density-constrained TDHF method to extract the nucleus-nucleus potentials and the excitation energy in each fragment. Results: Nucleus-nucleus potentials, nuclear contact times, masses and charges of the fragments, as well as their kinetic and excitation energies strongly depend on the orientation of the prolate 249Bk nucleus. Long contact times associated with fusion are observed in collisions of both projectiles with the side of the 249Bk nucleus, but not on collisions with its tip. The energy and impact parameter dependencies of the fragment properties, as well as their mass-angle and mass-total kinetic energy correlations are investigated. Conclusions: Entrance channel reaction dynamics are similar with both 48Ca and 50Ti projectiles. Both are expected to lead to the formation of a compound nucleus by fusion if they have enough energy to get in contact with the side of the 249Bk target.

  13. 50 CFR 665.249 - Lobster size and condition restrictions in Permit Area 2.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Lobster size and condition restrictions in... WESTERN PACIFIC Hawaii Fisheries § 665.249 Lobster size and condition restrictions in Permit Area 2. (a) Only spiny lobsters with a carapace length of 8.26 cm or greater may be retained (see Figure 1 to...

  14. 48 CFR 52.249-5 - Termination for Convenience of the Government (Educational and Other Nonprofit Institutions).

    Science.gov (United States)

    2010-10-01

    ... Convenience of the Government (Educational and Other Nonprofit Institutions). 52.249-5 Section 52.249-5... Convenience of the Government (Educational and Other Nonprofit Institutions). As prescribed in 49.502(d), insert the following clause: Termination for Convenience of the Government (Educational and...

  15. 48 CFR 1652.249-71 - FEHBP termination for convenience of the government-negotiated benefits contracts.

    Science.gov (United States)

    2010-10-01

    ... convenience of the government-negotiated benefits contracts. 1652.249-71 Section 1652.249-71 Federal... convenience of the government—negotiated benefits contracts. As prescribed in section 1649.101-71, the following clause shall be inserted in all FEHBP contracts. FEHBP Termination for Convenience of...

  16. 48 CFR 52.249-3 - Termination for Convenience of the Government (Dismantling, Demolition, or Removal of Improvements).

    Science.gov (United States)

    2010-10-01

    ... Convenience of the Government (Dismantling, Demolition, or Removal of Improvements). 52.249-3 Section 52.249-3... Convenience of the Government (Dismantling, Demolition, or Removal of Improvements). As prescribed in 49.502(b)(2), insert the following clause: Termination for Convenience of the Government...

  17. 17 CFR 249.509 - Form 9-M, consent to service of process by a partnership nonresident broker-dealer.

    Science.gov (United States)

    2010-04-01

    ... of process by a partnership nonresident broker-dealer. This form shall be filed pursuant to Rule 15b1... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form 9-M, consent to service of process by a partnership nonresident broker-dealer. 249.509 Section 249.509 Commodity...

  18. 14 CFR 249.21 - Preservation of records by public charter operators and overseas military personnel charter...

    Science.gov (United States)

    2010-01-01

    ... operators and overseas military personnel charter operators. 249.21 Section 249.21 Aeronautics and Space... public charter operators and overseas military personnel charter operators. Each operator authorized... in connection with the tour or series of tours. (d) All customer reservations records for each...

  19. Possible Synthesis of Z=117 through ~(48)Ca+~(249)Bk%通过~(48)Ca+~(249)Bk合成Z=117的可能性研究

    Institute of Scientific and Technical Information of China (English)

    张群武; 沈彩万; 赵恩广

    2009-01-01

    利用两步模型对可能合成Z=117的核反应~(48)Ca+~(249)Bk进行了研究.模型将熔合过程分为弹靶接触前的粘连过程和从弹靶接触到形成复合核的形成过程.结合统计蒸发模型,计算了297117蒸发数个中子的剩余截面.结果表明,在激发能E=31 MeV且复合核蒸发3中子时的剩余截面最大,为0.34 pb,已经可以用实验方法进行探测.%A possible way to synthesize superheavy element (Z=117) by using ~(48)Ca+~(249)Bk reaction is studied with two step model. The fusion process is divided into two steps- the sticking process that the projectile approaches to the target to get contacted with the target by passing over the Coulomb barrier, and the formation process that the di-nuclear system evolves from contact into compound nuclear state. Combined with the statistical evaporation model, the formation cross section of 297117 is calculated. The result shows that the residue for 3 neutron evaporation is 0.34 pb at excitation energy E* =31 MeV, which is detectable in laboratory.

  20. Swift broad band observations of the Black Hole transient GRS 1716-249

    Science.gov (United States)

    Del Santo, Melania; D'Ai', Antonino; Bassi, Tiziana; Segreto, Alberto; Belloni, Tomaso; Cusumano, Giancarlo; Parola, Valentina La

    2017-02-01

    We report on Swift observations of the ongoing outburst of the Black Hole Transient (BHT) GRS 1716-249 (ATel #9876, #9895). We analyzed both XRT and BAT data of three Swift ToO pointings performed on 2017 January 28, 29 and 30 (Target ID 34924, segments 1, 2, 3). The XRT count rate is about 90 count/s and therefore the observations have been performed in window-timing mode.

  1. Numerical simulation and experimental validation of arc welding of DMR-249A steel

    OpenAIRE

    2016-01-01

    The thermo-mechanical attributes of DMR-249A steel weld joints manufactured by shielded metal arc welding (SMAW) and activated gas tungsten arc welding (A-GTAW) processes were studied using Finite Element Model (FEM) simulation. The thermal gradients and residual stresses were analyzed with SYSWELD software using double ellipsoidal heat source distribution model. The numerically estimated temperature distribution was validated with online temperature measurements using thermocouples. The pred...

  2. Numerical simulation and experimental validation of arc welding of DMR-249A steel

    Directory of Open Access Journals (Sweden)

    Rishi Pamnani

    2016-08-01

    Full Text Available The thermo-mechanical attributes of DMR-249A steel weld joints manufactured by shielded metal arc welding (SMAW and activated gas tungsten arc welding (A-GTAW processes were studied using Finite Element Model (FEM simulation. The thermal gradients and residual stresses were analyzed with SYSWELD software using double ellipsoidal heat source distribution model. The numerically estimated temperature distribution was validated with online temperature measurements using thermocouples. The predicted residual stresses profile across the weld joints was compared with the values experimentally measured using non-destructive techniques. The measured and predicted thermal cycles and residual stress profile was observed to be comparable. The residual stress developed in double sided A-GTAW joint were marginally higher in comparison to five pass SMAW joint due to phase transformation associated with high heat input per weld pass for A-GTAW process. The present investigations suggest the applicability of numerical modeling as an effective approach for predicting the thermo-mechanical properties influenced by welding techniques for DMR-249A steel weld joints. The tensile, impact and micro-hardness tests were carried to compare the welds. Considering benefits of high productivity and savings of labor and cost associated with A-GTAW compared to SMAW process, the minor variation in residual stress build up of A-GTAW joint can be neglected to develop A-GTAW as qualified alternative welding technique for DMR-249A steel.

  3. Casein kinase 2α regulates multidrug resistance-associated protein 1 function via phosphorylation of Thr249.

    Science.gov (United States)

    Stolarczyk, Elzbieta I; Reiling, Cassandra J; Pickin, Kerry A; Coppage, Ryan; Knecht, Marc R; Paumi, Christian M

    2012-09-01

    We have shown previously that the function of Ycf1p, yeast ortholog of multidrug resistance-associated protein 1 (MRP1), is regulated by yeast casein kinase 2α (Cka1p) via phosphorylation at Ser251. In this study, we explored whether casein kinase 2α (CK2α), the human homolog of Cka1p, regulates MRP1 by phosphorylation at the semiconserved site Thr249. Knockdown of CK2α in MCF7-derived cells expressing MRP1 [MRP1 CK2α(-)] resulted in increased doxorubicin sensitivity. MRP1-dependent transport of leukotriene C(4) and estradiol-17β-d-glucuronide into vesicles derived from MRP1 CK2α(-) cells was decreased compared with MRP1 vesicles. Moreover, mutation of Thr249 to alanine (MRP1-T249A) also resulted in decreased MRP1-dependent transport, whereas a phosphomimicking mutation (MRP1-T249E) led to dramatic increase in MRP1-dependent transport. Studies in tissue culture confirmed these findings, showing increased intracellular doxorubicin accumulation in MRP1 CK2α(-) and MRP1-T249A cells compared with MRP1 cells. Inhibition of CK2 kinase by 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole resulted in increased doxorubicin accumulation in MRP1 cells, but not in MRP1 CK2α(-), MRP1-T249A, or MRP1-T249E cells, suggesting that CK2α regulates MRP1 function via phosphorylation of Thr249. Indeed, CK2α and MRP1 interact physically, and recombinant CK2 phosphorylates MRP1-derived peptide in vitro in a Thr249-dependent manner, whereas knockdown of CK2α results in decreased phosphorylation at MRP1-Thr249. The role of CK2 in regulating MRP1 was confirmed in other cancer cell lines where CK2 inhibition decreased MRP1-mediated efflux of doxorubicin and increased doxorubicin cytotoxicity. This study supports a model in which CK2α potentiates MRP1 function via direct phosphorylation of Thr249.

  4. Host competence and helicase activity differences exhibited by West Nile viral variants expressing NS3-249 amino acid polymorphisms.

    Directory of Open Access Journals (Sweden)

    Stanley A Langevin

    Full Text Available A single helicase amino acid substitution, NS3-T249P, has been shown to increase viremia magnitude/mortality in American crows (AMCRs following West Nile virus (WNV infection. Lineage/intra-lineage geographic variants exhibit consistent amino acid polymorphisms at this locus; however, the majority of WNV isolates associated with recent outbreaks reported worldwide have a proline at the NS3-249 residue. In order to evaluate the impact of NS3-249 variants on avian and mammalian virulence, multiple amino acid substitutions were engineered into a WNV infectious cDNA (NY99; NS3-249P and the resulting viruses inoculated into AMCRs, house sparrows (HOSPs and mice. Differential viremia profiles were observed between mutant viruses in the two bird species; however, the NS3-249P virus produced the highest mean peak viral loads in both avian models. In contrast, this avian modulating virulence determinant had no effect on LD50 or the neurovirulence phenotype in the murine model. Recombinant helicase proteins demonstrated variable helicase and ATPase activities; however, differences did not correlate with avian or murine viremia phenotypes. These in vitro and in vivo data indicate that avian-specific phenotypes are modulated by critical viral-host protein interactions involving the NS3-249 residue that directly influence transmission efficiency and therefore the magnitude of WNV epizootics in nature.

  5. Analysis of component blood transfusion in 249 cases of burned patients%249例烧伤患者的成分输血分析

    Institute of Scientific and Technical Information of China (English)

    赵小丽; 张晓萍; 郭萍; 张晓晶

    2015-01-01

    目的:分析烧伤患者血液成分使用情况,为指导烧伤患者在治疗过程中实施科学合理输血提供依据。方法回顾性分析甘肃省人民医院2013年8月至2014年5月收治的249例烧伤患者输注的血液成分种类、数量。结果249例烧伤患者共用血液成分3962.50 U ,其中红细胞683.00 U (17.24%),血浆3274.50 U (82.64%),血小板5.00 U (0.12%)。O型血患者成分血用量最多(34.80%),AB型血患者用量最少(12.22%)。3岁以下烧伤患儿例数最多,占40.16%;40~<55岁年龄段患者的输血量最大。结论该院烧伤患者血浆用量较多,临床医生应权衡输注价值和输注风险,正确把握输血治疗时机,根据患者情况制订不同的输血治疗方案。%Objective To analyze status of utilization of blood components in burned patients so as to provide references for sci‐entific and rational transfusion during therapy .Methods 249 cases of burned patients in the Gansu Provincial Hospital from Aug . 2013 to May 2014 were retrospectively analyzed ,including types and amount of component blood transfusion .Results The total blood components transfused were 3 962 .50 U ,including red blood cells 683 .00 U (accounted for 17 .24% ) ,plasma 3 274 .50 U (accounted for 82 .64% ) ,platelet 5 .00 U (accounted for 0 .12% ) .O‐type blood was the maximum amount (34 .80% ) ,AB‐type blood was the minimum amount (12 .22% ) .The most amount were found in burned patients under the age of three (40 .16% ) .The maximum amount of blood transfusion was found in patients from 40 - <55 years old .Conclusion Burn patients in this hospital use more plasma ,clinicians should measure the value and transfusion risk before infusion of plasma .And it is necessary to grasp the opportunity of transfusion therapy correctly and make different transfusion regimens for burned patients .

  6. Reinvestigation of the α-decays of 249Cf and 233U

    Science.gov (United States)

    Aka, A. Koua; Ardisson, G.; Barci, V.; El Samad, O.; Trubert, D.; Ahmad, I.

    1996-02-01

    The alpha-particle decay of 249Cf has been reinvestigated using coaxial and planar HPGe detectors. Energies and emission probabilities of thirty γ-rays were measured, of which nine are reported for the first time. All transitions have been included in the 245Cm level scheme suggested in this work: 14 excited states are found to be fed and assigned to 4 rotational bands. The Iπ = {11}/{2}- member of the {7}/{2} [743] Nilsson state was found to be fed at 772.3 keV. Alpha-particle transition probabilities were calculated from the revised 249Cf decay scheme. The alpha-particle decay of 233U has been reinvestigated using a UO 22+ source purified continuously from daughters by ion exchange chromatography. Energies and intensities of 178 γ-rays were determined, of which 49 are reported for the first time. γ-γ coincidence studies were also performed to help in the construction of the 229Th level scheme.

  7. Dipole Analysis of 249 High-Z SCP Union Supernovae According to the Expansion Center Model

    CERN Document Server

    Lorenzi, Luciano

    2011-01-01

    The topic of the paper is a preliminary analysis of 1743 data calculated for 249 High-z SCP Union supernovae, according to the expansion center model. The analysis of the ECM data set in Hubble units begins with 13 listed normal points corresponding to 13 z-bin samples at as many Hubble depths. Here the novel finding is a resulting clear drop in the average scattering of the SNe Ia absolute magnitudes M with the ECM Hubble depth D, after using the average trend computed in paper IX and here reconfirmed. Other correlations of the M scattering with the position in the sky are proposed as pointers for future investigations. Consequently, 13 ECM dipole tests on the 13 z-bin samples were carried out both with unweighed and weighed fittings. A further check was made through another ECM dipole test on the same 13 z bins, with Hubble depths D obtained by assuming M= according to paper IX and X. In conclusion the analysis of 249 SCP SNe confirms once again the expansion center model at any Hubble depth, including a s...

  8. Study of the properties of the superheavy nuclei Z = 117 produced in the 249Bk + 48Ca reaction

    Science.gov (United States)

    Oganessian, Yu. Ts.; Abdullin, F. Sh.; Alexander, C.; Binder, J.; Boll, R. A.; Dmitriev, S. N.; Ezold, J.; Felker, K.; Gostic, J. M.; Grzywacz, R. K.; Hamilton, J. H.; Henderson, R. A.; Itkis, M. G.; Miernik, K.; Miller, D.; Moody, K. J.; Polyakov, A. N.; Ramayya, A. V.; Roberto, J. B.; Ryabinin, M. A.; Rykaczewski, K. P.; Sagaidak, R. N.; Shaughnessy, D. A.; Shirokovsky, I. V.; Shumeiko, M. V.; Stoyer, M. A.; Stoyer, N. J.; Subbotin, V. G.; Sukhov, A. M.; Tsyganov, Yu. S.; Utyonkov, V. K.; Voinov, A. A.; Vostokin, G. K.

    2014-03-01

    The reaction of 249Bk with 48Ca have been reinvestigated to provide new evidence for the discovery of element 117 on a larger number of events. The experiments were performed at five projectile energies and with a total beam dose of 48Ca of about 4.6×1019. Two isotopes 293,294117 were synthesized in the 249Bk+48Ca reaction, providing excitation functions and α-decay spectra of the produced isotopes that establishes these nuclei to be the products of the 4n- and 3n-evaporation channels, respectively. Decay properties of 293,294117 and of all the daughter products agree with the data of the experiment in which these nuclei were synthesized for the first time in 2010. The new 289115 events, populated by α decay of 293117, demonstrate the same decay properties as those observed for 289115 produced in the 243Am(48Ca,2n) reaction thus providing crossbombardment evidence. In addition, a single decay of 294118 was observed from the reaction with 249Cf - a result of the in-growth of 249Cf in the 249Bk target.

  9. Study of the properties of the superheavy nuclei Z = 117 produced in the 249Bk + 48Ca reaction

    Directory of Open Access Journals (Sweden)

    Oganessian Yu. Ts.

    2014-03-01

    Full Text Available The reaction of 249Bk with 48Ca have been reinvestigated to provide new evidence for the discovery of element 117 on a larger number of events. The experiments were performed at five projectile energies and with a total beam dose of 48Ca of about 4.6×1019. Two isotopes 293,294117 were synthesized in the 249Bk+48Ca reaction, providing excitation functions and α-decay spectra of the produced isotopes that establishes these nuclei to be the products of the 4n- and 3n-evaporation channels, respectively. Decay properties of 293,294117 and of all the daughter products agree with the data of the experiment in which these nuclei were synthesized for the first time in 2010. The new 289115 events, populated by α decay of 293117, demonstrate the same decay properties as those observed for 289115 produced in the 243Am(48Ca,2n reaction thus providing crossbombardment evidence. In addition, a single decay of 294118 was observed from the reaction with 249Cf – a result of the in-growth of 249Cf in the 249Bk target.

  10. p53 ser249突变对小鼠EF细胞周期和凋亡的影响%Effect of p53 249 Arg to Ser mutation on cell cycle and apoptosis in mouse EF cells

    Institute of Scientific and Technical Information of China (English)

    吴智群; 李庆霞; 李臻; 于翠娟; 罗亚宁

    2009-01-01

    Objective To explore the effect of p53 249 Arg to Ser mutation on function of p53 in mouse EF cells.Methods Arg to Ser mutation was introduced into the p53 249 code by knock-in method.The ES cells with p53 249 Arg to Ser mutation were selected according to the homologues-recombination with RCR and Southern blot.The positive ES cells without a selection marker were injected into blastocysts recovered from Hprt-/-mice,which were derived from Hprt-deficient ES cells.The injected blastocysts then were implanted into pseudopregnant females.At embryonic day 14,MEFs were recovered from the embryos and cultured under the selection of HAT (0.016 mg of hypoxanthine/ml,0.01 mM aminopterin,0.0048 mg of thymidine/ml) and the cell cycle,apoptosis,and the relative protein expression were analyzed by flow cytometry and Western blot.Results 1) The EF cells with 249 Arg to Ser mutation were more resistant to the UV induced cell cycle arrest compared to the wild type EF cell (P<0.05).2) The EF cells with 249 Arg to Ser mutation were more resistant to the UV induced apoptosis compared to the wild type ES cell (P<0.05).3) The mutation did not affect the expression of p53 after UV but decrease the expression of BAX and p21 after UV.Conclusion Thep53 249 Arg to Ser mutation can disable the function of p53 but do not change the expression of p53 in EF cells.%目的 研究p53 249编码子突变对小鼠EF细胞p53功能和信号传导的影响.方法 利用基因打靶技术在小鼠ES细胞p53基因249编码子中引入点突变.使编码子249由Arg变成Ser,根据同源重组规律采用PCR或Southern方法筛选带有p53 249突变的阳性ES细胞,并通过测序确定该ES细胞的p53 249编码子已经由Arg变成Ser,然后将含突变而不含筛选标记的ES细胞微注射到从Hprt-/-小鼠收集的囊胚中,将注射过的囊胚植入假孕的雌性小鼠子宫,到第14天取小鼠胚胎EF细胞,用含HAT的培养液[DMEM含10%FCS,glutamine,antibiotics,50 mM mecaptoethanol

  11. 17 CFR 249.821 - Form PILOT, information required of self-regulatory organizations operating pilot trading systems...

    Science.gov (United States)

    2010-04-01

    ... required of self-regulatory organizations operating pilot trading systems pursuant to § 240.19b-5 of this... Associations § 249.821 Form PILOT, information required of self-regulatory organizations operating pilot trading systems pursuant to § 240.19b-5 of this chapter. This form shall be used by all...

  12. Production and decay of the heaviest odd-Z nuclei in the 249Bk + 48Ca reaction

    Science.gov (United States)

    Oganessian, Yu Ts; Abdullin, F. Sh; Alexander, C.; Binder, J.; Boll, R. A.; Dmitriev, S. N.; Ezold, J.; Felker, K.; Gostic, J. M.; Grzywacz, R. K.; Hamilton, J. H.; Henderson, R. A.; Itkis, M. G.; Miernik, K.; Miller, D.; Moody, K. J.; Polyakov, A. N.; Ramayya, A. V.; Roberto, J. B.; Ryabinin, M. A.; Rykaczewski, K. P.; Sagaidak, R. N.; Shaughnessy, D. A.; Shirokovsky, I. V.; Shumeiko, M. V.; Stoyer, M. A.; Stoyer, N. J.; Subbotin, V. G.; Sukhov, A. M.; Tsyganov, Yu S.; Utyonkov, V. K.; Voinov, A. A.; Vostokin, G. K.

    2015-02-01

    The reaction of 249Bk with 48Ca has been investigated with an aim of synthesizing and studying the decay properties of isotopes of the new element 117. The experiments were performed at five projectile energies (in two runs, in 2009-2010 and 2012) and with a total beam dose of 48Ca ions of about 9x1019 The experiments yielded data on a-decay characteristics and excitation functions of the produced nuclei that establish these to be 293117 and 294117 - the products of the 4n- and 3n-evaporation channels, respectively. In total, we have observed 20 decay chains of Z=117 nuclides. The cross sections were measured to be 1.1 pb for the 3n and 2.4 pb for the 4n-reaction channel. The new 289115 events, populated by α decay of 117, demonstrate the same decay properties as those observed for 115 produced in the 243Am(48Ca,2n) reaction thus providing cross-bombardment evidence. In addition, a single decay of 294118 was observed from the reaction with 249Cf - a result of the in-growth of 249Cf in the 249Bk target. The observed decay chain of 294118 is in good agreement with decay properties obtained in 2002-2005 in the experiments with the reaction 249Cf(48Ca,3n)294118. The energies and half-lives of the odd-Z isotopes observed in the 117 decay chains together with the results obtained for lower-Z superheavy nuclei demonstrate enhancement of nuclear stability with increasing neutron number towards the predicted new magic number N=184.

  13. Essentials and guidelines for clinical medical physics residency training programs: executive summary of AAPM Report Number 249.

    Science.gov (United States)

    Prisciandaro, Joann I; Willis, Charles E; Burmeister, Jay W; Clarke, Geoffrey D; Das, Rupak K; Esthappan, Jacqueline; Gerbi, Bruce J; Harkness, Beth A; Patton, James A; Peck, Donald J; Pizzutiello, Robert J; Sandison, George A; White, Sharon L; Wichman, Brian D; Ibbott, Geoffrey S; Both, Stefan

    2014-05-08

    There is a clear need for established standards for medical physics residency training. The complexity of techniques in imaging, nuclear medicine, and radiation oncology continues to increase with each passing year. It is therefore imperative that training requirements and competencies are routinely reviewed and updated to reflect the changing environment in hospitals and clinics across the country. In 2010, the AAPM Work Group on Periodic Review of Medical Physics Residency Training was formed and charged with updating AAPM Report Number 90. This work group includes AAPM members with extensive experience in clinical, professional, and educational aspects of medical physics. The resulting report, AAPM Report Number 249, concentrates on the clinical and professional knowledge needed to function independently as a practicing medical physicist in the areas of radiation oncology, imaging, and nuclear medicine, and constitutes a revision to AAPM Report Number 90. This manuscript presents an executive summary of AAPM Report Number 249.

  14. 浙江省249例聋校学生听力状况及病因学调查%An Etiological Study on Hearing Loss of 249 Deaf Students in Zhejiang Province

    Institute of Scientific and Technical Information of China (English)

    管锐瑞; 王晓艾; 王一鸣; 王永华

    2014-01-01

    目的:探讨浙江省聋校学生听力损失的病因、听力状况以及语言交流能力。明确该地区不同致聋因素,为因地制宜的开展耳聋的预防、干预等措施奠定基础,从而为将来开展从分子水平上进行耳聋的基因诊断和遗传咨询提供临床依据。方法采用调查问卷,听力测试等方法对浙江省249名聋校学生进行听力状况及病因学调查,并对其中佩戴助听器且有语言能力的56人进行言语测试。结果聋儿均为感应神经性聋,极重度聋占79.12%(197/249),重度聋占17.27%(43/249),中重度聋占3.21%(8/249),中度聋占0.40%(1/249)。先天性聋儿中,家族遗传性聋占7.23%(18/249),后天性聋儿中,药物性聋占36.54%(91/249),其中庆大霉素所占比例最高(31.87%)。佩戴助听器且有语言能力的56例聋儿,单音节词的平均正确率为62.1%,双音节词平均正确率为58.7%。结论聋校学生听力损失以极度聋、重度聋为多数,使用耳毒性药物是导致耳聋的主要原因;对聋儿进行早期诊断、早期佩戴助昕器、早期进行听力语言训练是使聋儿能够正常交流,融入主流社会的关键。%Objective To study the etiology, the hearing status and languagecommunication skills of the deaf students in Zhejiang province and to get the different factors of the deafness in the area in order to lay the foundation for getting more information about gene diagnosis and genetic counseling from the molecular level. Methods A total number of the 249 deaf students in Zhejiang province were examined with audiometer、investigated through questionnaire and other ways. Among them, 56 people of wearing hearing AIDS also had speech audiometry. Results The defect of the students is generally sensorineural, most of them are nonsyndromic deafness. The degrees of deafness could be ascertained with 197 (79.12%) students of profound deafness, 43 (17.27%) students

  15. Synthesis of the isotopes of elements 118 and 116 in the 249Cf and 245Cm+48Ca fusion reactions

    Energy Technology Data Exchange (ETDEWEB)

    Oganessian, Y T; Utyonkov, V K; Lobanov, Y V; Abdullin, F S; Polyakov, A N; Sagaidak, R N; Shirokovsky, I V; Tsyganov, Y S; Voinov, A A; Gulbekian, G G; Bogomolov, S L; Gikal, B N; Mezentsev, A N; Iliev, S; Subbotin, V G; Sukhov, A M; Subotic, K; Zagrebaev, V I; Vostokin, G K; Itkis, M G; Moody, K J; . Patin, J B; Shaughnessy, D A; Stoyer, M A; Stoyer, N J; Wilk, P A; Kenneally, J M; Landrum, J H; Wild, J F; Lougheed, R W

    2006-01-31

    The decay properties of {sup 290}116 and {sup 291}116, and the dependence of their production cross sections on the excitation energies of the compound nucleus, {sup 293}116, have been measured in the {sup 245}Cm({sup 48}Ca,xn){sup 293-x}116 reaction. These isotopes of element 116 are the decay daughters of element 118 isotopes, which are produced via the {sup 249}Cf+{sup 48}Ca reaction. They performed the element 118 experiment at two projectile energies, corresponding to {sup 297}118 compound nucleus excitation energies of E* = 29.2 {+-} 2.5 and 34.4 {+-} 2.3 MeV. During an irradiation with a total beam dose of 4.1 x 10{sup 19} {sup 48}Ca projectiles, three similar decay chains consisting of two or three consecutive {alpha} decays and terminated by a spontaneous fission (SF) with high total kinetic energy of about 230 MeV were observed. The three decay chains originated from the even-even isotope {sup 294}118 (E{sub {alpha}} = 11.65 {+-} 0.06 MeV, T{sub {alpha}} = 0.89{sub -0.31}{sup +1.07} ms) produced in the 3n-evaporation channel of the {sup 249}Cf+{sup 48}Ca reaction with a maximum cross section of 0.5{sub -0.3}{sup +1.6} pb.

  16. Detection of human papilloma virus in 249 cases of patients with genital warts%249例生殖器疣患者人乳头瘤病毒检测分析

    Institute of Scientific and Technical Information of China (English)

    李蕾; 邹先彪

    2016-01-01

    Objective To investigate the distribution of human papilloma virus (HPV) genotypes from outpatients with genital wart in Beijing.Method Flow cytometry HPV genotyping technique were used to detect and identify HPV genotypes from individual lesions. Result Among 249 cases of genital warts, 232 (93.17%) were DNA HPV positive. The positive rate of HPV single type was 63.86%, the positive rate of multiple type of HPV was 36.14%. The infection rate of low-risk HPV was 55.4%, in which HPV6 and HPV11 were the most popular genotypes. HPV16, HPV58, HPV18 were the most prevalent high-risk genotypes.Conclusion The peak of HPV infection concentrates in sexually active population younger than 40 years old. HPV6, HPV11 and HPV16 are the predominant genotypes for genital wart in Beijing.%目的:调查生殖器疣患者人乳头瘤病毒(human papilloma virus,HPV)感染特点,为HPV感染的预防和诊治提供理论依据。方法采用流式荧光HPV基因分型技术检测249例生殖器疣患者皮损组织中HPV的型别。结果249例生殖器疣患者中,232例(93.17%)HPV DNA阳性。单一型感染率为63.86%,复合型感染率为36.14%。低危型HPV阳性率为55.4%,其中以HPV6、HPV11最多;高危型中以HPV16最多,其次为HPV58、HPV18型。结论本地区生殖器HPV感染集中于40岁以下性活跃期的人群。以单一型感染为主,最常见HPV6、HPV11和HPV16型感染。

  17. Factors influencing resuscitation and growth of heat injured Listeria monocytogenes 13-249 in sous vide cooked beef.

    Science.gov (United States)

    Hansen, T B; Knøchel, S

    2001-01-22

    The growth of Listeria monocytogenes 13-249 in vacuum-packed, minced beef was investigated as a function of degree of heat injury (including no injury i.e. uncooked beef), growth phase (logarithmic and late stationary phase), pH (5.6 and 6.2), and storage temperature (3, 10 and 20 degrees C) during a storage period of 30 days. Late logarithmic and late stationary phase cultures of L. monocytogenes 13-249 showed similar growth in refrigerated, vacuum-packed, raw minced beef with a high pH (6.2). In normal pH (5.6) beef there was no growth at 3 degrees C while growth at 10 and 20 degrees C was only observed for logarithmic phase cultures. Heat injured late stationary phase cultures with 95-99.9% injured cells in the surviving population (as measured by differential plating on enriched vs. selective media after sous vide cooking) did not grow or repair sublethal injuries in sous vide cooked beef at 3 degrees C while repair and growth took place at 10 as well as at 20 degrees C. In logarithmic phase cultures heat injury occurred very rapidly and > or = 99.9% heat injury was observed in all trials in spite of much lower pasteurization values and fewer log10 reductions compared with late stationary phase cultures. Regardless of growth phase, all cultures where a high degree of heat injury (> or = 99.9%) was observed, did not subsequently grow in the beef product at 3 or 10 degrees C within 30 days. Growth of heat injured cultures preexposed to heat shock (46 degrees C, 30 min) or slowly rising temperatures (0.3 degrees C min(-1)) before heat injury was also investigated. Heat shocked or heat adapted cultures generally responded in the same manner as non-stressed cultures (no growth at 3 degrees C) except that a longer lag phase was observed in beef processed at slowly rising temperatures and in normal pH beef at 10 degrees C. Although processing at slowly rising temperatures may slightly increase the survival of L. monocytogenes 13-249 in cooked beef, there seem to be no

  18. Mutations of residues 249 and 256 in VP2 are involved in the replication and virulence of infectious Bursal disease virus.

    Directory of Open Access Journals (Sweden)

    Xiaole Qi

    Full Text Available Infectious bursal disease virus (IBDV is a pathogen of worldwide significance to the poultry industry. Although the PDE and PFG domains of the capsid protein VP2 contribute significantly to virulence and fitness, the detailed molecular basis for the pathogenicity of IBDV is still not fully understood. Because residues 253 and 284 of VP2 are not the sole determinants of virulence, we hypothesized that other residues involved in virulence and fitness might exist in the PDE and PFG domains of VP2. To test this, five amino acid changes selected by sequence comparison of the PDE and PFG domains of VP2 were introduced individually using a reverse genetics system into the virulent strain (rGx-F9VP2. Then reverse mutations of the selected residues 249 and 256 were introduced individually into the attenuated strain (rGt. Seven modified viruses were generated and evaluated in vitro (CEF cells and in vivo (SPF chicken. For residue 249, Q249R could elevate in vitro and reduce in vivo the replication of rGx-F9VP2 while R249Q could reduce in vitro and elevate in vivo the replication of rGt; meanwhile Q249R reduced the virulence of rGx-F9VP2 while R249Q increased the virulence of rGt, which indicated that residue 249 significantly contributed to the replication and virulence of IBDV. For residue 256, I256V could elevate in vitro and reduce in vivo the replication of rGx-F9VP2 while V256I could reduce in vitro but didn't change in vivo the replication of rGt; although V256I didn't increase the virulence of rGt, I256V obviously reduced the virulence of virulent IBDV. The present results demonstrate for the first time, to different extent, residues 249 and 256 of VP2 are involved in the replication efficiency and virulence of IBDV; this is not only beneficial to further understanding of pathogenic mechanism but also to the design of newly tailored vaccines against IBDV.

  19. 17 CFR 249.210 - Form 10 and Form 10-SB, general form for registration of securities pursuant to section 12 (b) or...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form 10 and Form 10-SB... Securities on National Securities Exchanges and Similar Matters § 249.210 Form 10 and Form 10-SB, general..., 78o(d), 78w)) Editorial Note: For Federal Register citations affecting Form 10 and Form 10-SB, see...

  20. 莫高窟第249窟窟顶壁画图像学研究%A Research on the Top Murals of Cave No. 249 in the Mogao Grottoes Based on Iconology

    Institute of Scientific and Technical Information of China (English)

    岳锋

    2012-01-01

    Although the scholars at home and abroad have studied the main images on the top murals of Cave No. 249 in the Mogao Grottoes from different perspectives, they couldn't reach an agreement. At present, no conclusion can be made on these images in academic circle. However, by integrating the predecessor' s research achievement and studying the combination principles of these images at a macro level, an illustration of iconology may take its initial shape based on the theory of iconology proposed by Erwin Panofsky. To sum up, the "combination" of the images from the different cultural origins converged into a whole and demonstrated a shared signifieanee concealed in the images. Namely, it is a cosmic illusion of a fusion of the exotic Buddhism thought and local Taoism thought.%围绕莫高窟第249窟窟顶壁画的主要图像,中外学者采用了不同的研究方法,从不同的视角进行了深入研究,形成了不同的结论。目前,学术界对这些图像尚不能形成统一的定论,但是基于欧文·帕诺夫斯基的图像学研究三个阶段的基本理论,综合前人的研究成果,从宏观上把握这些图像的组合原则,可以初步形成一个图像学的解释:不同文化渊源图像的“混用”汇聚成一个整体,共同表达了一个隐藏在图像背后的意义,即一个融合了外来佛教思想和本土道教思想的古代敦煌人心中的宇宙幻象。

  1. X-ray nova MAXI J1828-249. Evolution of the broadband spectrum during its 2013-2014 outburst

    CERN Document Server

    Grebenev, S A; Burenin, R A; Krivonos, R A; Mescheryakov, A V

    2016-01-01

    Based on data from the SWIFT, INTEGRAL, MAXI/ISS orbital observatories, and the ground-based RTT-150 telescope, we have investigated the broadband (from the optical to the hard X-ray bands) spectrum of the X-ray nova MAXI J1828-249 and its evolution during the outburst of the source in 2013-2014. The optical and infrared emissions from the nova are shown to be largely determined by the extension of the power-law component responsible for the hard X-ray emission. The contribution from the outer cold regions of the accretion disk, even if the X-ray heating of its surface is taken into account, turns out to be moderate during the source's "high" state (when a soft blackbody emission component is observed in the X-ray spectrum) and is virtually absent during its "low" ("hard") state. This result suggests that much of the optical and infrared emissions from such systems originates in the same region of main energy release where their hard X-ray emission is formed. This can be the Compton or synchro-Compton radiati...

  2. 249例前列腺液细菌培养及药敏结果分析%Analysis of bacterial culture and drug sensitivity results of 249 prostate lfuid samples

    Institute of Scientific and Technical Information of China (English)

    杨彦磊; 王瑞; 张卫星

    2014-01-01

    目的:分析前列腺液细菌培养结果,探索细菌感染在慢性细菌性前列腺炎病因学中的意义,对临床慢性细菌性前列腺炎的治疗提供参考。方法嘱前列腺炎患者停用抗生素3d以上,清洗尿道外口,按摩前列腺液作细菌培养及药敏试验。结果249份前列腺液标本中,98份细菌培养阳性,阳性率39.4%。检出细菌98株,其中革兰阳性菌92株,占93.9%,革兰阴性杆菌6株,占6.1%。78株葡萄球菌的体外药敏试验结果显示,仅对万古霉素、利奈唑胺和替考拉宁敏感,而对青霉素、阿奇霉素、红霉素和克拉霉素全部耐药。对其他种类抗生素亦有不同程度的耐药。6株革兰阴性杆菌药敏结果显示,对常见的抗生素均敏感。结论革兰阳性葡萄球菌及棒状杆菌可能在慢性细菌性前列腺炎病原学中占有一定比例,抗生素的耐药性应引起高度重视。%Objective To analyze bacterial culture results of prostate fluid samples and explore the etiological significance of bacterial infection for clinical treatment of chronic bacterial prostatitis. Methods Patients with prostatitis were asked to stop antibiotics treatment for more than 3 days and clean their external orifice of urethra prior to prostatic fluid collecting. Prostatic fluid samples were collected for bacterial culture and drug sensitivity test. Results In all 249 prostatic fluid samples, 98 of them showed positive result in bacterial culture. The positive rate was 39.4%, including 92 strains of Gram-positive Bacterial strains, accounting for 93.9%, 6 strains of Gram-negative bacterial strains, accounting for 6.1%. Drug sensitivity results from 78 cases of staphylococcal strains showed they were sensitive to vancomycin, linezolid and teicoplanin, but resistant to penicilinc, azithromycin, erythromycin, clarithromycin and other antibiotics. Drug sensitivity results from 6 strains of gram negative bacterial showed they were

  3. Analysis of 249 Cases With Nutritional and Iron Deficiency Anemia%婴、幼儿营养性缺铁性贫血249例相关因素分析

    Institute of Scientific and Technical Information of China (English)

    郑建梅; 杨道科

    2009-01-01

    目的 探讨不同月龄婴、幼儿的营养性缺铁性贫血(nutritional iron deficiency anemia)发生情况及其相关因素.方法 选择2004年1月1日至2006年12月31日在郑州市妇幼保健院儿童保健门诊接受规范4∶2∶1保健的1 254例1~6个月(A组,n=540)、6~12个月(B组,n=360)、12~18个月(C组,n=354)儿童为研究对象(本研究遵循的程序符合郑州市妇幼保健院人体试验委员会所制定的伦理学标准,得到该委员会批准,分组征得受试对象监护人的知情同意,并与其签署临床研究知情同意书).对其母乳喂养、辅食添加等情况进行问卷调查(自行设计),并采用世界卫生组织(WHO)推荐的氰化高铁法测定血红蛋白(hemoglobin,Hb)含量,同时回顾性追踪母亲孕期保健资料,对采集资料进行汇总、统计学处理和分析. 结果 营养性缺铁性贫血总检出率为19.86%(249/1 254), 其中A,B,C组儿童营养性缺铁性贫血检出率分别为26.11%(141/540),19.17%(69/360),11.02%(39/354),随年龄增加,营养性缺铁性贫血发生率下降.单因素分析显示,A组婴儿中,纯母乳喂养儿(n=414)和非纯母乳喂养儿(n=126)缺铁性贫血检出率分别为22.46%(93/414)和38.10%(48/126),两者比较,差异有显著意义(P<0.05).A组纯母乳喂养儿中,及时和过晚添加辅食儿(n=309 vs. n=105)的营养性缺铁性贫血检出率分别为16.50%(51/309),40.00%(42/105),两者比较,差异有显著意义(P<0.01).母亲孕期保健资料回顾性分析结果显示,249例营养性缺铁性贫血婴、幼儿中,孕妇孕晚期缺铁性贫血为78例(31.5%).结论 婴、幼儿饮食结构不合理和母亲孕晚期缺铁性贫血,是导致婴、幼儿营养性缺铁性贫血的重要影响因素.加强围生期保健, 提倡婴儿期母乳喂养的同时注意适时(4~6个月龄时)添加辅食,是减少婴儿期营养性缺铁性贫血的有效措施.

  4. 温州地区原发性肝细胞癌TP53基因249密码子突变研究%Analysis of mutation of TP53 gene codon 249 in primary hepatocellular carcinoma in Wenzhou area

    Institute of Scientific and Technical Information of China (English)

    胡伟建; 郑亦胡; 鲍海力; 朱椰凡; 张启瑜

    2016-01-01

    目的 检测温州地区原发性肝细胞癌的TP53基因249密码子突变情况,并探讨其在肝细胞癌中所起的作用及其临床意义.方法 收集石蜡包埋的原发性肝细胞癌组织120例,应用Sanger测序技术检测突变情况.运用Spearman检验分析肿瘤组织中TP53基因249密码子突变与原发性肝细胞癌患者临床病理特征之间的相关性.结果 TP53基因249密码子在120例肝癌组织中总突变率为3.33% (4/120),进一步分析显示TP53基因249密码子突变与肝细胞癌患者的临床病理因素未发现存在相关性(P> 0.05).结论 在温州地区,TP53基因249密码子突变为非高发事件,未发现其与原发性肝细胞癌的进展相关.

  5. Biological, chemical and other data collected aboard the THOMAS G. THOMPSON during cruise TN249 in the Bering Sea from 2010-05-10 to 2010-06-15 (NODC Accession 0117397)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC accession 0117397 includes biological, chemical, optical and physical data collected aboard the THOMAS G. THOMPSON during cruise TN249 in the Bering Sea from...

  6. Eleven new heaviest isotopes of elements Z = 105 to Z = 117 identified among the products of 249Bk+48Ca reactions

    Energy Technology Data Exchange (ETDEWEB)

    Oganessian, Yuri Ts. [FLNR-JINR, Russia; Abdullin, F. Sh. [Joint Institute for Nuclear Research, Dubna, Russia; Bailey, P. D. [Oak Ridge National Laboratory (ORNL); Benker, D. E. [Oak Ridge National Laboratory (ORNL); Bennett, M. E. [University of Nevada, Las Vegas; Dmitriev, S. [FLNR-JINR, Russia; Ezold, Julie G. [Oak Ridge National Laboratory (ORNL); Hamilton, J. H. [Vanderbilt University; Henderson, R. [Lawrence Livermore National Laboratory (LLNL); Itkis, M. G. [FLNR-JINR, Russia; Lobanov, Yu. V. [Joint Institute for Nuclear Research, Dubna, Russia; Mezentsev, A. N. [Joint Institute for Nuclear Research, Dubna, Russia; Moody, K. [Lawrence Livermore National Laboratory (LLNL); Nelson, S. L. [Lawrence Livermore National Laboratory (LLNL); Polyakov, A. N. [Joint Institute for Nuclear Research, Dubna, Russia; Porter, C. E. [Oak Ridge National Laboratory (ORNL); Ramayya, A. V. [Vanderbilt University; Riley, F. D. [Oak Ridge National Laboratory (ORNL); Roberto, James B [ORNL; Ryabinin, M. A. [Research Institute of Atomic Reactors, Dimitrovgrad, Russia; Rykaczewski, Krzysztof Piotr [ORNL; Taylor, R [Oak Ridge National Laboratory (ORNL); Tsyganov, Yu. S. [Joint Institute for Nuclear Research, Dubna, Russia; Utyonkov, V. [FLNR-JINR, Russia; Voinov, A. A. [Joint Institute for Nuclear Research, Dubna, Russia; Vostokin, G. K. [Joint Institute for Nuclear Research, Dubna, Russia; Wilk, P. A. [Lawrence Livermore National Laboratory (LLNL)

    2011-01-01

    The heaviest isotopes of elements Z = 117 to Z = 105, 294117, 293117, 290115, 289115, 286113, 285113, 282Rg, 281Rg, 278Mt, 274Bh, and 270Db, were identified by means of the Dubna gas-filled recoil separator among the products of the 249Bk + 48Ca reaction. The details of the observed six decay chains, indicating the production and decay of isotopes 293117 and 294117, are presented and discussed. The decay energies and resulting half-lives of these new nuclei show a strong rise of stability with increasing neutron number, validating the concept of the island of enhanced stability for superheavy nuclei.

  7. Dense Fe-Rich Ejecta in Supernova Remnants DEM L238 and DEM L249: A New Class of Type Ia Supernova?

    CERN Document Server

    Borkowski, K J; Reynolds, S P

    2006-01-01

    We present observations of two LMC supernova remnants (SNRs), DEM L238 and DEM L249, with the Chandra and XMM-Newton X-ray satellites. Bright central emission, surrounded by a faint shell, is present in both remnants. The central emission has an entirely thermal spectrum dominated by strong Fe L-shell lines, with the deduced Fe abundance in excess of solar and not consistent with the LMC abundance. This Fe overabundance leads to the conclusion that DEM L238 and DEM L249 are remnants of thermonuclear (Type Ia) explosions. The shell emission originates in gas swept up and heated by the blast wave. A standard Sedov analysis implies about 50 solar masses in both swept-up shells, SNR ages between 10,000 and 15,000 yr, low (< 0.05 cm^-3) preshock densities, and subluminous explosions with energies of 3x10^50 ergs. The central Fe-rich supernova ejecta are close to collisional ionization equilibrium. Their presence is unexpected, because standard Type Ia SNR models predict faint ejecta emission with short ionizati...

  8. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015 : a systematic analysis for the Global Burden of Disease Study 2015

    NARCIS (Netherlands)

    Wang, Haidong; Naghavi, Mohsen; Allen, Christine; Barber, Ryan M.; Bhutta, Zulfiqar A.; Carter, Austin; Casey, Daniel C.; Charlson, Fiona J.; Chen, Alan Zian; Coates, Matthew M.; Coggeshall, Megan; Dandona, Lalit; Dicker, Daniel J.; Erskine, Holly E.; Ferrari, Alize J.; Fitzmaurice, Christina; Foreman, Kyle; Forouzanfar, Mohammad H.; Fraser, Maya S.; Pullman, Nancy; Gething, Peter W.; Goldberg, Ellen M.; Graetz, Nicholas; Haagsma, Juanita A.; Hay, Simon I.; Huynh, Chantal; Johnson, Catherine; Kassebaum, Nicholas J.; Kinfu, Yohannes; Kulikoff, Xie Rachel; Kutz, Michael; Kyu, Hmwe H.; Larson, Heidi J.; Leung, Janni; Liang, Xiaofeng; Lim, Stephen S.; Lind, Margaret; Lozano, Rafael; Marquez, Neal; Mensah, George A.; Mikesell, Joe; Mokdad, Ali H.; Mooney, Meghan D.; Nguyen, Grant; Nsoesie, Elaine; Pigott, David M.; Pinho, Christine; Roth, Gregory A.; Salomon, Joshua A.; Sandar, Logan; Silpakit, Naris; Sligar, Amber; Sorensen, Reed J. D.; Stanaway, Jeffrey; Steiner, Caitlyn; Teeple, Stephanie; Thomas, Bernadette A.; Troeger, Christopher; VanderZanden, Amelia; Vollset, Stein Emil; Wanga, Valentine; Whiteford, Harvey A.; Wolock, Timothy; Zoeckler, Leo; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw Ferede; Abreu, Daisy M. X.; Abu-Raddad, Laith J.; Abyu, Gebre Yitayih; Achoki, Tom; Adelekan, Ademola Lukman; Ademi, Zanfina; Adou, Arsene Kouablan; Adsuar, Jose C.; Afanvi, Kossivi Agbelenko; Afshin, Ashkan; Agardh, Emilie Elisabet; Agarwal, Arnav; Agrawal, Anurag; Kiadaliri, Aliasghar Ahmad; Ajala, Oluremi N.; Akanda, All Shafqat; Akinyemi, Rufus Olusola; Akinyemiju, Tomi F.; Akseer, Nadia; Al Lami, Faris Hasan; Alabed, Samer; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore K. M.; Alasfoor, Deena; Aldhahri, Saleh Fahed; Aldridge, Robert William; Alegretti, Miguel Angel; Aleman, Alicia V.; Alemu, Zewdie Aderaw; Alexander, Lily T.; Alhabib, Samia; Ali, Raghib; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A.; Martin, Elena Alvarez; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Amegah, Adeladza Kofi; Ameh, Emmanuel A.; Amini, Heresh; Ammar, Walid; Amrock, Stephen Marc; Andersen, Hjalte H.; Anderson, Benjamin; Anderson, Gregory M.; Antonio, Carl Abelardo T.; Aregay, Atsede Fantahun; Arnlov, Johan; Arsenijevic, Valentina S. Arsic; Al Artaman, Ali; Asayesh, Hamid; Asghar, Rana Jawad; Atique, Suleman; Arthur Avokpaho, Euripide Frinel G.; Awasthi, Ashish; Azzopardi, Peter; Bacha, Umar; Badawi, Alaa; Bahit, Maria C.; Balakrishnan, Kalpana; Banerjee, Amitava; Barac, Aleksandra; Barker-Collo, Suzanne L.; Barnighausen, Till; Barregard, Lars; Barrero, Lope H.; Basu, Arindam; Basu, Sanjay; Bayou, Yibeltal Tebekaw; Bazargan-Hejazi, Shahrzad; Beardsley, Justin; Bedi, Neeraj; Beghi, Ettore; Belay, Haileeyesus Adamu; Bell, Brent; Bell, Michelle L.; Bello, Aminu K.; Bennett, Derrick A.; Bensenor, Isabela M.; Berhane, Adugnaw; Bernabe, Eduardo; Betsu, Balem Demtsu; Beyene, Addisu Shunu; Bhala, Neeraj; Bhalla, Ashish; Biadgilign, Sibhatu; Bikbov, Boris; Bin Abdulhak, Aref A.; Biroscak, Brian J.; Biryukov, Stan; Bjertness, Espen; Blore, Jed D.; Blosser, Christopher D.; Bohensky, Megan A.; Borschmann, Rohan; Bose, Dipan; Bourne, Rupert R. A.; Brainin, Michael; Brayne, Carol E. 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Filipa; de Jager, Pieter; De Leo, Diego; Degenhardt, Louisa; Dellavalle, Robert P.; Deribe, Kebede; Deribew, Amare; Dharmaratne, Samath D.; Dhillon, Preet K.; Diaz-Torne, Cesar; Ding, Eric L.; dos Santos, Kadine Priscila Bender; Dossou, Edem; Driscoll, Tim R.; Duan, Leilei; Dubey, Manisha; Bartholow, Bruce; Ellenbogen, Richard G.; Lycke, Christian; Elyazar, Iqbal; Endries, Aman Yesuf; Ermakov, Sergey Petrovich; Eshrati, Babak; Esteghamati, Alireza; Estep, Kara; Faghmous, Imad D. A.; Fahimi, Saman; Jose, Emerito; Farid, Talha A.; Sa Farinha, Carla Sofia e; Faro, Andre; Farvid, Maryam S.; Farzadfar, Farshad; Feigin, Valery L.; Fereshtehnejad, Seyed-Mohammad; Fernandes, Jefferson G.; Fernandes, Joao C.; Fischer, Florian; Fitchett, Joseph R. A.; Flaxman, Abraham; Foigt, Nataliya; Fowkes, F. Gerry R.; Franca, Elisabeth Barboza; Franklin, Richard C.; Friedman, Joseph; Frostad, Joseph; Hirst, Thomas; Futran, Neal D.; Gall, Seana L.; Gambashidze, Ketevan; Gamkrelidze, Amiran; Ganguly, Parthasarathi; Gankpe, Fortune Gbetoho; Gebre, Teshome; Gebrehiwot, Tsegaye Tsewelde; Gebremedhin, Amanuel Tesfay; Gebru, Alemseged Aregay; Geleijnse, Johanna M.; Gessner, Bradford D.; Ghoshal, Aloke Gopal; Gibney, Katherine B.; Gillum, Richard F.; Gilmour, Stuart; Giref, Ababi Zergaw; Giroud, Maurice; Gishu, Melkamu Dedefo; Giussani, Giorgia; Glaser, Elizabeth; Godwin, William W.; Gomez-Dantes, Hector; Gona, Philimon; Goodridge, Amador; Gopalani, Sameer Vali; Gosselin, Richard A.; Gotay, Carolyn C.; Goto, Atsushi; Gouda, Hebe N.; Greaves, Felix; Gugnani, Harish Chander; Gupta, Rahul; Gupta, Rajeev; Gupta, Vipin; Gutierrez, Reyna A.; Hafezi-Nejad, Nima; Haile, Demewoz; Hailu, Alemayehu Desalegne; Hailu, Gessessew Bugssa; Halasa, Yara A.; Hamadeh, Randah Ribhi; Hamidi, Samer; Hancock, Jamie; Handal, Alexis J.; Hankey, Graeme J.; Hao, Yuantao; Harb, Hilda L.; Harikrishnan, Sivadasanpillai; Haro, Josep Maria; Havmoeller, Rasmus; Heckbert, Susan R.; Heredia-Pi, Ileana Beatriz; Heydarpour, Pouria; Hilderink, Henk B. M.; Hoek, Hans W.; Hogg, Robert S.; Horino, Masako; Horita, Nobuyuki; Hosgood, H. Dean; Hotez, Peter J.; Hoy, Damian G.; Hsairi, Mohamed; Htet, Aung Soe; Than Htike, Maung Maung; Hu, Guoqing; Huang, Cheng; Huang, Hsiang; Huiart, Laetitia; Husseini, Abdullatif; Huybrechts, Inge; Huynh, Grace; Iburg, Kim Moesgaard; Innos, Kaire; Inoue, Manami; Iyer, Veena J.; Jacobs, Troy A.; Jacobsen, Kathryn H.; Jahanmehr, Nader; Jakovljevic, Mihajlo B.; James, Peter; Javanbakht, Mehdi; Jayaraman, Sudha P.; Jayatilleke, Achala Upendra; Jeemon, Panniyammakal; Jensen, Paul N.; Jha, Vivekanand; Jiang, Guohong; Jiang, Ying; Jibat, Tariku; Jimenez-Corona, Aida; Jonas, Jost B.; Joshi, Tushar Kant; Kabir, Zubair; Karnak, Ritul; Kan, Haidong; Kant, Surya; Karch, Andre; Karema, Corine Kakizi; Karimkhani, Chante; Karletsos, Dimitris; Karthikeyan, Ganesan; Kasaeian, Amir; Katibeh, Marzieh; Kaul, Anil; Kawakami, Norito; Kayibanda, Jeanne Francoise; Keiyoro, Peter Njenga; Kemmer, Laura; Kemp, Andrew Haddon; Kengne, Andre Pascal; Keren, Andre; Kereselidze, Maia; Kesavachandran, Chandrasekharan Nair; Khader, Yousef Saleh; Khalil, Ibrahim A.; Khan, Abdur Rahman; Khan, Ejaz Ahmad; Khang, Young-Ho; Khera, Sahil; Muthafer Khoja, Tawfik Ahmed; Kieling, Christian; Kim, Daniel; Kim, Yun Jin; Kissela, Brett M.; Kissoon, Niranjan; Knibbs, Luke D.; Knudsen, Ann Kristin; Kokubo, Yoshihiro; Kolte, Dhaval; Kopec, Jacek A.; Kosen, Soewarta; Koul, Parvaiz A.; Koyanagi, Ai; Krog, Norun Hjertager; Defo, Barthelemy Kuate; Bicer, Burcu Kucuk; Kudom, Andreas A.; Kuipers, Ernst J.; Kulkarni, Veena S.; Kumar, G. Anil; Kwan, Gene F.; Lal, Aparna; Lal, Dharmesh Kumar; Lalloo, Ratilal; Lam, Hilton; Lam, Jennifer O.; Langan, Sinead M.; Lansingh, Van C.; Larsson, Anders; Laryea, Dennis Odai; Latif, Asma Abdul; Lawrynowicz, Alicia Elena Beatriz; Leigh, James; Levi, Miriam; Li, Yongmei; Lindsay, M. Patrice; Lipshultz, Steven E.; Liu, Patrick Y.; Liu, Shiwei; Liu, Yang; Lo, Loon-Tzian; Logroscino, Giancarlo; Lotufo, Paulo A.; Lucas, Robyn M.; Lunevicius, Raimundas; Lyons, Ronan A.; Ma, Stefan; Pedro Machado, Vasco Manuel; Mackay, Mark T.; MacLachlan, Jennifer H.; Abd El Razek, Hassan Magdy; Abd El Razek, Mohammed Magdy; Majdan, Marek; Majeed, Azeem; Malekzadeh, Reza; Ayele Manamo, Wondimu Ayele; Mandisarisa, John; Mangalam, Srikanth; Mapoma, Chabila C.; Marcenes, Wagner; Margolis, David Joel; Martin, Gerard Robert; Martinez-Raga, Jose; Marzan, Melvin Barrientos; Masiye, Felix; Mason-Jones, Amanda J.; Massano, Joao; Matzopoulos, Richard; Mayosi, Bongani M.; McGarvey, Stephen Theodore; McGrath, John J.; Mckee, Martin; McMahon, Brian J.; Meaney, Peter A.; Mehari, Alem; Mehndiratta, Man Mohan; Mena-Rodriguez, Fabiola; Mekonnen, Alemayehu B.; Melaku, Yohannes Adama; Memiah, Peter; Memish, Ziad A.; Mendoza, Walter; Meretoja, Atte; Meretoja, Tuomo J.; Mhimbira, Francis Apolinary; Micha, Renata; Miller, Ted R.; Mirarefin, Mojde; Misganaw, Awoke; Mock, Charles N.; Abdulmuhsin Mohammad, Karzan; Mohammadi, Alireza; Mohammed, Shafiu; Mohan, Viswanathan; Mola, Glen Liddell D.; Monasta, Lorenzo; Montanez Hernandez, Julio Cesar; Montero, Pablo; Montico, Marcella; Montine, Thomas J.; Moradi-Lakeh, Maziar; Morawska, Lidia; Morgan, Katherine; Mori, Rintaro; Mozaffarian, Dariush; Mueller, Ulrich; Satyanarayana Murthy, Gudlavalleti Venkata; Murthy, Srinivas; Musa, Kamarul Imran; Nachega, Jean B.; Nagel, Gabriele; Naidoo, Kovin S.; Naik, Nitish; Naldi, Luigi; Nangia, Vinay; Nash, Denis; Nejjari, Chakib; Neupane, Subas; Newton, Charles R.; Newton, John N.; Ng, Marie; Ngalesoni, Frida Namnyak; Ngirabega, Jean de Dieu; Quyen Le Nguyen, [Unknown; Nisar, Muhammad Imran; Nkamedjie Pete, Patrick Martial; Nomura, Marika; Norheim, Ole F.; Norman, Paul E.; Norrving, Bo; Nyakarahuka, Luke; Ogbo, Felix Akpojene; Ohkubo, Takayoshi; Ojelabi, Foluke Adetola; Olivares, Pedro R.; Olusanya, Bolajoko Olubukunola; Olusanya, Jacob Olusegun; Opio, John Nelson; Oren, Eyal; Ortiz, Alberto; Osman, Majdi; Ota, Erika; Ozdemir, Raziye; Pa, Mahesh; Pandian, Jeyaraj D.; Pant, Puspa Raj; Papachristou, Christina; Park, Eun-Kee; Park, Jae-Hyun; Parry, Charles D.; Parsaeian, Mahboubeh; Caicedo, Angel J. 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Alex; Rafay, Anwar; Rahimi, Kazem; Rahimi-Movaghar, Vafa; Rahman, Mahfuzar; Rahman, Mohammad Hifz Ur; Rahman, Sajjad Ur; Rai, Rajesh Kumar; Rajavi, Zhale; Rajsic, Sasa; Raju, Murugesan; Rakovac, Ivo; Rana, Saleem M.; Ranabhat, Chhabi L.; Rangaswamy, Thara; Rao, Puja; Rao, Sowmya R.; Refaat, Amany H.; Rehm, Jurgen; Reitsma, Marissa B.; Remuzzi, Giuseppe; Resnikofff, Serge; Ribeiro, Antonio L.; Ricci, Stefano; Blancas, Maria Jesus Rios; Roberts, Bayard; Roca, Anna; Rojas-Rueda, David; Ronfani, Luca; Roshandel, Gholamreza; Rothenbacher, Dietrich; Roy, Ambuj; Roy, Nawal K.; Ruhago, George Mugambage; Sagar, Rajesh; Saha, Sukanta; Sahathevan, Ramesh; Saleh, Muhammad Muhammad; Sanabria, Juan R.; Sanchez-Nino, Maria Dolores; Sanchez-Riera, Lidia; Santos, Itamar S.; Sarmiento-Suarez, Rodrigo; Sartorius, Benn; Satpathy, Maheswar; Savic, Miloje; Sawhney, Monika; Schaub, Michael P.; Schmidt, Maria Ines; Schneider, Ione J. C.; Schottker, Ben; Schutte, Aletta E.; Schwebel, David C.; Seedat, Soraya; Sepanlou, Sadaf G.; Servan-Mori, Edson E.; Shackelford, Katya A.; Shaddick, Gavin; Shaheen, Amira; Shahraz, Saeid; Shaikh, Masood Ali; Shakh-Nazarova, Marina; Sharma, Rajesh; She, Jun; Sheikhbahaei, Sara; Shen, Jiabin; Shen, Ziyan; Shepard, Donald S.; Sheth, Kevin N.; Shetty, Balakrishna P.; Shi, Peilin; Shibuya, Kenji; Shin, Min-Jeong; Shiri, Rahman; Shiue, Ivy; Shrime, Mark G.; Sigfusdottir, Inga Dora; Silberberg, Donald H.; Silva, Diego Augusto Santos; Silveira, Dayane Gabriele Alves; Silverberg, Jonathan I.; Simard, Edgar P.; Singh, Abhishek; Singh, Gitanjali M.; Singh, Jasvinder A.; Singh, Om Prakash; Singh, Prashant Kumar; Singh, Virendra; Soneji, Samir; Soreide, Kjetil; Soriano, Joan B.; Sposato, Luciano A.; Sreeramareddy, Chandrashekhar T.; Stathopoulou, Vasiliki; Stein, Dan J.; Stein, Murray B.; Stranges, Saverio; Stroumpoulis, Konstantinos; Sunguya, Bruno F.; Sur, Patrick; Swaminathan, Soumya; Sykes, Bryan L.; Szoeke, Cassandra E. I.; Tabares-Seisdedos, Rafael; Tabb, Karen M.; Takahashi, Ken; Takala, Jukka S.; Talongwa, Roberto Tchio; Tandon, Nikhil; Tavakkoli, Mohammad; Taye, Bineyam; Taylor, Hugh R.; Ao, Braden J. Te; Tedla, Bemnet Amare; Tefera, Worku Mekonnen; Ten Have, Margreet; Terkawi, Abdullah Sulieman; Tesfay, Fisaha Haile; Tessema, Gizachew Assefa; Thomson, Alan J.; Thorne-Lyman, Andrew L.; Thrift, Amanda G.; Thurston, George D.; Tillmann, Taavi; Tirschwell, David L.; Tonelli, Marcello; Topor-Madry, Roman; Topouzis, Fotis; Nx, Jeffrey Allen Towb; Traebert, Jefferson; Tran, Bach Xuan; Truelsen, Thomas; Trujillo, Ulises; Tura, Abera Kenay; Tuzcu, Emin Murat; Uchendu, Uche S.; Ukwaja, Kingsley N.; Undurraga, Eduardo A.; Uthman, Olalekan A.; Van Dingenen, Rita; Van Donkelaar, Aaron; Vasankari, Tommi; Vasconcelos, Ana Maria Nogales; Venketasubramanian, Narayanaswamy; Vidavalur, Ramesh; Vijayakumar, Lakshmi; Villalpando, Salvador; Violante, Francesco S.; Vlassov, Vasiliy Victorovich; Wagner, Joseph A.; Wagner, Gregory R.; Wallin, Mitchell T.; Wang, Linhong; Watkins, David A.; Weichenthal, Scott; Weiderpass, Elisabete; Weintraub, Robert G.; Werdecker, Andrea; Westerman, Ronny; White, Richard A.; Wijeratne, Tissa; Wilkinson, James D.; Williams, Hywel C.; Wiysonge, Charles Shey; Woldeyohannes, Solomon Meseret; Wolfe, Charles D. A.; Won, Sungho; Wong, John Q.; Woolf, Anthony D.; Xavier, Denis; Xiao, Qingyang; Xu, Gelin; Yakob, Bereket; Yalew, Ayalnesh Zemene; Yan, Lijing L.; Yano, Yuichiro; Yaseri, Mehdi; Ye, Pengpeng; Yebyo, Henock Gebremedhin; Yip, Paul; Yirsaw, Biruck Desalegn; Yonemoto, Naohiro; Yonga, Gerald; Younis, Mustafa Z.; Yu, Shicheng; Zaidi, Zoubida; Zaki, Maysaa El Sayed; Zannad, Faiez; Zavala, Diego E.; Zeeb, Hajo; Zeleke, Berihun M.; Zhang, Hao; Zodpey, Sanjay; Zonies, David; Zuhlke, Liesl Joanna; Vos, Theo; Lopez, Alan D.; Murray, Christopher J. L.

    2016-01-01

    Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes

  9. Deep VLT spectroscopy of the z=2.49 Radio Galaxy MRC 2104-242 Evidence for a metallicity gradient in its extended emission line region

    CERN Document Server

    Overzier, R; Kurk, J D; De Breuck, C

    2001-01-01

    We present spectroscopic observations of the rest-frame UV line emission around radio galaxy MRC 2104-242 at z=2.49, obtained with FORS1 on VLT Antu. The morphology of the halo is dominated by two spatially resolved regions. Lya is extended by >12 arcsec along the radio axis, CIV and HeII are extended by ~8 arcsec. The overall spectrum is typical for that of high redshift radio galaxies. The most striking spatial variation is that NV is present in the spectrum of the region associated with the center of the galaxy hosting the radio source, the northern region, while absent in the southern region. Assuming that the gas is photoionized by a hidden quasar, the difference in NV emission can be explained by a metallicity gradient within the halo. This is consistent with a scenario in which the gas is associated with a massive cooling flow or originates from the debris of the merging of two or more galaxies.

  10. Crystal structure of apatite type Ca2.49Nd7.51(SiO46O1.75

    Directory of Open Access Journals (Sweden)

    Thu Hoai Le

    2016-02-01

    Full Text Available The title compound, Ca2+xNd8–x(SiO46O2–0.5x (x = 0.49, was synthesized at 1873 K and rapidly quenched to room temperature. Its structure has been determined using single-crystal X-ray diffraction and compared with results reported using neutron and X-ray powder diffraction from samples prepared by slow cooling. The single-crystal structure from room temperature data was found to belong to the space group P63/m and has the composition Ca2.49Nd7.51(SiO46O1.75 [dicalcium octaneodymium hexakis(orthosilicate dioxide], being isotypic with natural apatite and the previously reported Ca2Nd8(SiO46O2 and Ca2.2Nd7.8(SiO46O1.9. The solubility limit of calcium in the equilibrium state at 1873 K was found to occur at a composition of Ca2+xNd8–x(SiO46O2–0.5x, where x = 0.49.

  11. Ca48+Bk249 Fusion Reaction Leading to Element Z =117: Long-Lived α-Decaying Db270 and Discovery of Lr266

    Science.gov (United States)

    Khuyagbaatar, J.; Yakushev, A.; Düllmann, Ch. E.; Ackermann, D.; Andersson, L.-L.; Asai, M.; Block, M.; Boll, R. A.; Brand, H.; Cox, D. M.; Dasgupta, M.; Derkx, X.; Di Nitto, A.; Eberhardt, K.; Even, J.; Evers, M.; Fahlander, C.; Forsberg, U.; Gates, J. M.; Gharibyan, N.; Golubev, P.; Gregorich, K. E.; Hamilton, J. H.; Hartmann, W.; Herzberg, R.-D.; Heßberger, F. P.; Hinde, D. J.; Hoffmann, J.; Hollinger, R.; Hübner, A.; Jäger, E.; Kindler, B.; Kratz, J. V.; Krier, J.; Kurz, N.; Laatiaoui, M.; Lahiri, S.; Lang, R.; Lommel, B.; Maiti, M.; Miernik, K.; Minami, S.; Mistry, A.; Mokry, C.; Nitsche, H.; Omtvedt, J. P.; Pang, G. K.; Papadakis, P.; Renisch, D.; Roberto, J.; Rudolph, D.; Runke, J.; Rykaczewski, K. P.; Sarmiento, L. G.; Schädel, M.; Schausten, B.; Semchenkov, A.; Shaughnessy, D. A.; Steinegger, P.; Steiner, J.; Tereshatov, E. E.; Thörle-Pospiech, P.; Tinschert, K.; Torres De Heidenreich, T.; Trautmann, N.; Türler, A.; Uusitalo, J.; Ward, D. E.; Wegrzecki, M.; Wiehl, N.; Van Cleve, S. M.; Yakusheva, V.

    2014-05-01

    The superheavy element with atomic number Z =117 was produced as an evaporation residue in the Ca48+Bk249 fusion reaction at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. The radioactive decay of evaporation residues and their α-decay products was studied using a detection setup that allowed measuring decays of single atomic nuclei with half-lives between sub-μs and a few days. Two decay chains comprising seven α decays and a spontaneous fission each were identified and are assigned to the isotope 117294 and its decay products. A hitherto unknown α-decay branch in Db270 (Z =105) was observed, which populated the new isotope Lr266 (Z =103). The identification of the long-lived (T1/2=1.0-0.4+1.9 h) α-emitter Db270 marks an important step towards the observation of even more long-lived nuclei of superheavy elements located on an "island of stability."

  12. 48Ca+249Bk fusion reaction leading to element Z = 117: long-lived α-decaying 270Db and discovery of 266Lr.

    Science.gov (United States)

    Khuyagbaatar, J; Yakushev, A; Düllmann, Ch E; Ackermann, D; Andersson, L-L; Asai, M; Block, M; Boll, R A; Brand, H; Cox, D M; Dasgupta, M; Derkx, X; Di Nitto, A; Eberhardt, K; Even, J; Evers, M; Fahlander, C; Forsberg, U; Gates, J M; Gharibyan, N; Golubev, P; Gregorich, K E; Hamilton, J H; Hartmann, W; Herzberg, R-D; Heßberger, F P; Hinde, D J; Hoffmann, J; Hollinger, R; Hübner, A; Jäger, E; Kindler, B; Kratz, J V; Krier, J; Kurz, N; Laatiaoui, M; Lahiri, S; Lang, R; Lommel, B; Maiti, M; Miernik, K; Minami, S; Mistry, A; Mokry, C; Nitsche, H; Omtvedt, J P; Pang, G K; Papadakis, P; Renisch, D; Roberto, J; Rudolph, D; Runke, J; Rykaczewski, K P; Sarmiento, L G; Schädel, M; Schausten, B; Semchenkov, A; Shaughnessy, D A; Steinegger, P; Steiner, J; Tereshatov, E E; Thörle-Pospiech, P; Tinschert, K; Torres De Heidenreich, T; Trautmann, N; Türler, A; Uusitalo, J; Ward, D E; Wegrzecki, M; Wiehl, N; Van Cleve, S M; Yakusheva, V

    2014-05-02

    The superheavy element with atomic number Z=117 was produced as an evaporation residue in the (48)Ca+(249)Bk fusion reaction at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. The radioactive decay of evaporation residues and their α-decay products was studied using a detection setup that allowed measuring decays of single atomic nuclei with half-lives between sub-μs and a few days. Two decay chains comprising seven α decays and a spontaneous fission each were identified and are assigned to the isotope (294)117 and its decay products. A hitherto unknown α-decay branch in (270)Db (Z = 105) was observed, which populated the new isotope (266)Lr (Z = 103). The identification of the long-lived (T(1/2) = 1.0(-0.4)(+1.9) h) α-emitter (270)Db marks an important step towards the observation of even more long-lived nuclei of superheavy elements located on an "island of stability."

  13. Convergent Evolution of Fern-Specific Mitochondrial Group II Intron atp1i361g2 and Its Ancient Source Paralogue rps3i249g2 and Independent Losses of Intron and RNA Editing among Pteridaceae

    Science.gov (United States)

    Zumkeller, Simon Maria; Knoop, Volker; Knie, Nils

    2016-01-01

    Mitochondrial intron patterns are highly divergent between the major land plant clades. An intron in the atp1 gene, atp1i361g2, is an example for a group II intron specific to monilophytes (ferns). Here, we report that atp1i361g2 is lost independently at least 4 times in the fern family Pteridaceae. Such plant organelle intron losses have previously been found to be accompanied by loss of RNA editing sites in the flanking exon regions as a consequence of genomic recombination of mature cDNA. Instead, we now observe that RNA editing events in both directions of pyrimidine exchange (C-to-U and U-to-C) are retained in atp1 exons after loss of the intron in Pteris argyraea/biaurita and in Actiniopteris and Onychium. We find that atp1i361g2 has significant similarity with intron rps3i249g2 present in lycophytes and gymnosperms, which we now also find highly conserved in ferns. We conclude that atp1i361g2 may have originated from the more ancestral rps3i249g2 paralogue by a reverse splicing copy event early in the evolution of monilophytes. Secondary structure elements of the two introns, most characteristically their domains III, show strikingly convergent evolution in the monilophytes. Moreover, the intron paralogue rps3i249g2 reveals relaxed evolution in taxa where the atp1i361g2 paralogue is lost. Our findings may reflect convergent evolution of the two related mitochondrial introns exerted by co-evolution with an intron-binding protein simultaneously acting on the two paralogues. PMID:27492234

  14. Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families

    DEFF Research Database (Denmark)

    Hansen, Thomas van Overeem; Jønson, Lars; Albrechtsen, Anders;

    2010-01-01

    identified in this population. Here, we describe the identification of a novel disease-causing BRCA1 nucleotide 4803delCC/c.4684delCC mutation in a Greenlandic Inuit with ovarian cancer. The mutation introduces a frameshift and a premature stop at codon 1572. We have also identified a BRCA1 nucleotide 249T...

  15. Solution of the Skyrme-Hartree-Fock-Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis. (VII) HFODD (v2.49s): a new version of the program

    CERN Document Server

    Schunck, N; McDonnell, J; Satula, W; Sheikh, J A; Staszczak, A; Stoitsov, M; Toivanen, P

    2011-01-01

    We describe the new version (v2.49s) of the code HFODD which solves the nuclear Skyrme Hartree-Fock (HF) or Skyrme Hartree-Fock-Bogolyubov (HFB) problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, we have implemented the following physics features: (i) the isospin mixing and projection, (ii) the finite temperature formalism for the HFB and HF+BCS methods, (iii) the Lipkin translational energy correction method, (iv) the calculation of the shell correction. A number of specific numerical methods have also been implemented in order to deal with large-scale multi-constraint calculations and hardware limitations: (i) the two-basis method for the HFB method, (ii) the Augmented Lagrangian Method (ALM) for multi-constraint calculations, (iii) the linear constraint method based on the approximation of the RPA matrix for multi-constraint calculations, (iv) an interface with the axial and parity-conserving Skyrme-HFB code HFBTHO, (v) the mixing of the HF or HFB matrix elements instead...

  16. Daytime E-Region Irregularities During the 22 July 2009 Solar Eclipse over Chung-Li (24.9°N, 121.2°E, a Moderate Mid-Latitude Station

    Directory of Open Access Journals (Sweden)

    Potula Sree Brahmanandam

    2013-01-01

    Full Text Available The 22 July 2009 solar eclipse with an obscuration of > 83% at Chung-Li (24.9¢XN, 121.2¢XE, Dip 35¢XN in Taiwan during noon hours has provided a unique opportunity for us to examine its impact on E-region irregularities which were observed simultaneously by the 52 MHz coherent radar and a co-located ionosonde. Significant observations revealed that the daytime E-region strong backscatter echoes at multiple heights and a sudden intensification of the weak sporadic E-layer during the 22 July 2009 solar eclipse. These results follow the research findings of Patra et al. (2009. As the incident solar radiation suddenly blocked by intruding Moon during solar eclipse events that would generally create night-like ionospheric conditions, it is surmised that the E-region irregularities were indeed induced by the eclipse associated effects. The induced effects resulted in faster recombination of molecular ions, generation of gravity waves and electric fields that could have created a conducive environment to excite plasma irregularities through a gradient-drift instability mechanism. The vertical shears of radar Doppler velocity and the peak radar backscatter at the node of Doppler velocity shear, as resolved by the coherent scatter radar with interferometer technique, were possibly due to the upward propagating gravity waves and wave-induced polarization electric fields. The present observational results should not only be highly useful to ascertain plausible mechanisms responsible for nighttime E-region irregularities, but also provided evidence that a solar eclipse could generate E-region plasma irregularities over temperate mid-latitudes for the first time.

  17. 14 CFR 249.2 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... constitute integral links in developing the history of, or facts regarding, financial transactions or... other acquisition. Supporting papers (records) means any group of documentary papers, such as...

  18. 47 CFR 24.249 - Payment issues.

    Science.gov (United States)

    2010-10-01

    ... issues. (a) Timing. On the day that a PCS entity files its prior coordination notice (PCN) in accordance with § 101.103(d) of this chapter, it must file a copy of the PCN with the clearinghouse....

  19. 49 CFR 173.249 - Bromine.

    Science.gov (United States)

    2010-10-01

    ... tank code T22 (see § 172.102 of this subchapter) or specification IM 101 portable tanks conforming with... from nickel-clad or lead-lined steel plate. Nickel cladding or lead lining must be on the inside of...

  20. 7 CFR 249.6 - Participant eligibility.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Participant Eligibility... congregate nutrition services are provided, as categorically eligible to receive SFMNP benefits....

  1. 32 CFR 249.5 - Procedures.

    Science.gov (United States)

    2010-07-01

    ... that information. (c) Location of meetings and access controls. To a large degree location of and... meetings will be provided to the Defense Technical Information Center, Defense Logistics Agency, Cameron Station, Alexandria, VA 22304 for secondary distribution....

  2. 7 CFR 249.19 - Investigations.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Monitoring and Review of State... appropriate, a review of pertinent practices and policies of any State and local agency, the...

  3. 7 CFR 249.7 - Nondiscrimination.

    Science.gov (United States)

    2010-01-01

    ... title); and (vi) Applicable FNS Instructions, including requirements for racial and ethnic participation... agency's racial and ethnic participation data (as required by title VI of the Civil Rights Act of 1964... discrimination, under the SFMNP: (i) Title VI of the Civil Rights Act of 1964; (ii) Title IX of the...

  4. 7 CFR 249.2 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... as prunes (dried plums), raisins (dried grapes), sun-dried tomatoes, or dried chili peppers are not considered eligible foods. Potted fruit or vegetable plants, potted or dried herbs, wild rice, nuts of...

  5. Solution of the Skyrme-Hartree-Fock-Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis.. (VII) HFODD (v2.49t): A new version of the program

    Science.gov (United States)

    Schunck, N.; Dobaczewski, J.; McDonnell, J.; Satuła, W.; Sheikh, J. A.; Staszczak, A.; Stoitsov, M.; Toivanen, P.

    2012-01-01

    We describe the new version (v2.49t) of the code HFODD which solves the nuclear Skyrme-Hartree-Fock (HF) or Skyrme-Hartree-Fock-Bogolyubov (HFB) problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, we have implemented the following physics features: (i) the isospin mixing and projection, (ii) the finite-temperature formalism for the HFB and HF + BCS methods, (iii) the Lipkin translational energy correction method, (iv) the calculation of the shell correction. A number of specific numerical methods have also been implemented in order to deal with large-scale multi-constraint calculations and hardware limitations: (i) the two-basis method for the HFB method, (ii) the Augmented Lagrangian Method (ALM) for multi-constraint calculations, (iii) the linear constraint method based on the approximation of the RPA matrix for multi-constraint calculations, (iv) an interface with the axial and parity-conserving Skyrme-HFB code HFBTHO, (v) the mixing of the HF or HFB matrix elements instead of the HF fields. Special care has been paid to using the code on massively parallel leadership class computers. For this purpose, the following features are now available with this version: (i) the Message Passing Interface (MPI) framework, (ii) scalable input data routines, (iii) multi-threading via OpenMP pragmas, (iv) parallel diagonalization of the HFB matrix in the simplex-breaking case using the ScaLAPACK library. Finally, several little significant errors of the previous published version were corrected. New version program summaryProgram title:HFODD (v2.49t) Catalogue identifier: ADFL_v3_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADFL_v3_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public Licence v3 No. of lines in distributed program, including test data, etc.: 190 614 No. of bytes in distributed program, including test data, etc.: 985 898 Distribution

  6. 1935 15' Quad #249 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  7. 40 CFR 180.249 - Alachlor; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ..., meat 0.02 Sheep, fat 0.02 Sheep, meat byproducts 0.02 Sheep, meat 0.02 Sorghum grain, forage 2.0..., dry 0.1 Beans, succulent lima 0.1 Cattle, fat 0.02 Cattle, meat byproducts 0.02 Cattle, meat 0.02 Corn... seed 0.03 Cowpea, forage 5.0 Cowpea, hay 5.0 Egg 0.02 Goat, fat 0.02 Goat, meat byproducts 0.02...

  8. Dicty_cDB: SHJ249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available |AX251183.1 Sequence 151 from Patent WO0168912. 50 2e-05 3 BD452704 |BD452704.1 Diagnosis of Diseases... |BD460593.1 Diagnosis of Diseases Associated with Cell Cycle. 36 0.011 4 dna upd

  9. Dicty_cDB: AHB249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available haliana DNA chromoso... 130 4e-40 AK227321_1( AK227321 |pid:none) Arabidopsis thaliana mRNA for hypo... 130 ...4e-40 AK221976_1( AK221976 |pid:none) Arabidopsis thaliana mRNA for hypo... 130 4e-40 AK230210_1( AK230210 |...pid:none) Arabidopsis thaliana mRNA for hypo... 130 7e-40 AK101151_1( AK101151 |p

  10. 7 CFR 249.24 - Data safeguarding procedures.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions... authority) that administer food, nutrition, or other assistance programs that serve persons...

  11. 7 CFR 2.49 - Administrator, Rural Housing Service.

    Science.gov (United States)

    2010-01-01

    ... chapter II), with respect to claims of the Rural Housing Service. (8) Administer responsibilities and...) Section 109 of the Act (42 U.S.C. 9609), with respect to the assessment of civil penalties for violations... issuing notes to the Secretary of the Treasury for the purposes the Rural Development Insurance Fund...

  12. Dicty_cDB: CHE249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available nce update 2002.10.25 Translated Amino Acid sequence wptgyynsnihhtlfivlll*nltyflfiklnnsl*ir**GDLKKESFFFTLYFV...ino Acid sequence (All Frames) Frame A: wptgyynsnihhtlfivlll*nltyflfiklnnsl*ir**GDLKKESFFFTLYFVHYKKK --- ---

  13. 7 CFR 249.17 - Management evaluations and reviews.

    Science.gov (United States)

    2010-01-01

    ....17 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP... SFMNP and the WIC Farmers' Market Nutrition Program are in operation, these reviews may be...

  14. Dicty_cDB: CHP249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available seq. ID - 3' end seq. - Length of 3' end seq. - Connected seq. ID - Connected seq. - Length of connected seq. - Full length Seq ID - Full length Seq. - Length of full length seq. - ...

  15. Dicty_cDB: CHB249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available TTAGATTTCTTGGCATAGTAAAAAATTAC sequence update 2002.10.25 Translated Amino Acid sequence hcwptgiyftthsivcv*YK...VLFA DLDFLA**ki Translated Amino Acid sequence (All Frames) Frame A: hcwptgiyftth

  16. Dicty_cDB: SFF249 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 67E10.y2 949 - Juvenile leaf and shoot cDNA from Steve Moose Zea mays cDNA, mRNA sequence. 42 5e-13 4 CA2696... mRNA sequence. 42 1e-12 4 BI478599 |BI478599.1 949067E10.x1 949 - Juvenile leaf and shoot cDNA from Steve M

  17. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

    Science.gov (United States)

    Speliotes, Elizabeth K; Willer, Cristen J; Berndt, Sonja I; Monda, Keri L; Thorleifsson, Gudmar; Jackson, Anne U; Lango Allen, Hana; Lindgren, Cecilia M; Luan, Jian'an; Mägi, Reedik; Randall, Joshua C; Vedantam, Sailaja; Winkler, Thomas W; Qi, Lu; Workalemahu, Tsegaselassie; Heid, Iris M; Steinthorsdottir, Valgerdur; Stringham, Heather M; Weedon, Michael N; Wheeler, Eleanor; Wood, Andrew R; Ferreira, Teresa; Weyant, Robert J; Segrè, Ayellet V; Estrada, Karol; Liang, Liming; Nemesh, James; Park, Ju-Hyun; Gustafsson, Stefan; Kilpeläinen, Tuomas O; Yang, Jian; Bouatia-Naji, Nabila; Esko, Tõnu; Feitosa, Mary F; Kutalik, Zoltán; Mangino, Massimo; Raychaudhuri, Soumya; Scherag, Andre; Smith, Albert Vernon; Welch, Ryan; Zhao, Jing Hua; Aben, Katja K; Absher, Devin M; Amin, Najaf; Dixon, Anna L; Fisher, Eva; Glazer, Nicole L; Goddard, Michael E; Heard-Costa, Nancy L; Hoesel, Volker; Hottenga, Jouke-Jan; Johansson, Asa; Johnson, Toby; Ketkar, Shamika; Lamina, Claudia; Li, Shengxu; Moffatt, Miriam F; Myers, Richard H; Narisu, Narisu; Perry, John R B; Peters, Marjolein J; Preuss, Michael; Ripatti, Samuli; Rivadeneira, Fernando; Sandholt, Camilla; Scott, Laura J; Timpson, Nicholas J; Tyrer, Jonathan P; van Wingerden, Sophie; Watanabe, Richard M; White, Charles C; Wiklund, Fredrik; Barlassina, Christina; Chasman, Daniel I; Cooper, Matthew N; Jansson, John-Olov; Lawrence, Robert W; Pellikka, Niina; Prokopenko, Inga; Shi, Jianxin; Thiering, Elisabeth; Alavere, Helene; Alibrandi, Maria T S; Almgren, Peter; Arnold, Alice M; Aspelund, Thor; Atwood, Larry D; Balkau, Beverley; Balmforth, Anthony J; Bennett, Amanda J; Ben-Shlomo, Yoav; Bergman, Richard N; Bergmann, Sven; Biebermann, Heike; Blakemore, Alexandra I F; Boes, Tanja; Bonnycastle, Lori L; Bornstein, Stefan R; Brown, Morris J; Buchanan, Thomas A; Busonero, Fabio; Campbell, Harry; Cappuccio, Francesco P; Cavalcanti-Proença, Christine; Chen, Yii-Der Ida; Chen, Chih-Mei; Chines, Peter S; Clarke, Robert; Coin, Lachlan; Connell, John; Day, Ian N M; den Heijer, Martin; Duan, Jubao; Ebrahim, Shah; Elliott, Paul; Elosua, Roberto; Eiriksdottir, Gudny; Erdos, Michael R; Eriksson, Johan G; Facheris, Maurizio F; Felix, Stephan B; Fischer-Posovszky, Pamela; Folsom, Aaron R; Friedrich, Nele; Freimer, Nelson B; Fu, Mao; Gaget, Stefan; Gejman, Pablo V; Geus, Eco J C; Gieger, Christian; Gjesing, Anette P; Goel, Anuj; Goyette, Philippe; Grallert, Harald; Grässler, Jürgen; Greenawalt, Danielle M; Groves, Christopher J; Gudnason, Vilmundur; Guiducci, Candace; Hartikainen, Anna-Liisa; Hassanali, Neelam; Hall, Alistair S; Havulinna, Aki S; Hayward, Caroline; Heath, Andrew C; Hengstenberg, Christian; Hicks, Andrew A; Hinney, Anke; Hofman, Albert; Homuth, Georg; Hui, Jennie; Igl, Wilmar; Iribarren, Carlos; Isomaa, Bo; Jacobs, Kevin B; Jarick, Ivonne; Jewell, Elizabeth; John, Ulrich; Jørgensen, Torben; Jousilahti, Pekka; Jula, Antti; Kaakinen, Marika; Kajantie, Eero; Kaplan, Lee M; Kathiresan, Sekar; Kettunen, Johannes; Kinnunen, Leena; Knowles, Joshua W; Kolcic, Ivana; König, Inke R; Koskinen, Seppo; Kovacs, Peter; Kuusisto, Johanna; Kraft, Peter; Kvaløy, Kirsti; Laitinen, Jaana; Lantieri, Olivier; Lanzani, Chiara; Launer, Lenore J; Lecoeur, Cecile; Lehtimäki, Terho; Lettre, Guillaume; Liu, Jianjun; Lokki, Marja-Liisa; Lorentzon, Mattias; Luben, Robert N; Ludwig, Barbara; Manunta, Paolo; Marek, Diana; Marre, Michel; Martin, Nicholas G; McArdle, Wendy L; McCarthy, Anne; McKnight, Barbara; Meitinger, Thomas; Melander, Olle; Meyre, David; Midthjell, Kristian; Montgomery, Grant W; Morken, Mario A; Morris, Andrew P; Mulic, Rosanda; Ngwa, Julius S; Nelis, Mari; Neville, Matt J; Nyholt, Dale R; O'Donnell, Christopher J; O'Rahilly, Stephen; Ong, Ken K; Oostra, Ben; Paré, Guillaume; Parker, Alex N; Perola, Markus; Pichler, Irene; Pietiläinen, Kirsi H; Platou, Carl G P; Polasek, Ozren; Pouta, Anneli; Rafelt, Suzanne; Raitakari, Olli; Rayner, Nigel W; Ridderstråle, Martin; Rief, Winfried; Ruokonen, Aimo; Robertson, Neil R; Rzehak, Peter; Salomaa, Veikko; Sanders, Alan R; Sandhu, Manjinder S; Sanna, Serena; Saramies, Jouko; Savolainen, Markku J; Scherag, Susann; Schipf, Sabine; Schreiber, Stefan; Schunkert, Heribert; Silander, Kaisa; Sinisalo, Juha; Siscovick, David S; Smit, Jan H; Soranzo, Nicole; Sovio, Ulla; Stephens, Jonathan; Surakka, Ida; Swift, Amy J; Tammesoo, Mari-Liis; Tardif, Jean-Claude; Teder-Laving, Maris; Teslovich, Tanya M; Thompson, John R; Thomson, Brian; Tönjes, Anke; Tuomi, Tiinamaija; van Meurs, Joyce B J; van Ommen, Gert-Jan; Vatin, Vincent; Viikari, Jorma; Visvikis-Siest, Sophie

    2010-11-01

    Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and ∼ 2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci associated with body mass index (P < 5 × 10⁻⁸), one of which includes a copy number variant near GPRC5B. Some loci (at MC4R, POMC, SH2B1 and BDNF) map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor. Furthermore, genes in other newly associated loci may provide new insights into human body weight regulation.

  18. Preserved urethral plate urethroplasty for failed hypospadias repair: report of 249 cases

    Institute of Scientific and Technical Information of China (English)

    ZHANG Wei-ping; TIAN Jun; LI Ming-lei; SONG Hong-cheng; BAI Ji-wu; HUANG Cheng-ru; SUN Ning

    2008-01-01

    @@ Hypospadias is one of the most common abnormalities of the external male genitalia but is very difficult to repair. Hypospadias reoperation is also a common practice for pediatric urologists, though repair of hypospadias at reoperation is much more difficult.

  19. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    DEFF Research Database (Denmark)

    Speliotes, Elizabeth K; Willer, Cristen J; Berndt, Sonja I

    2010-01-01

    in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci associated with body mass index (P R, POMC, SH2B1 and BDNF) map near key hypothalamic regulators...

  20. 14 CFR 249.20 - Preservation of records by certificated air carriers.

    Science.gov (United States)

    2010-01-01

    ... to explain, journal entries; entry numbers Do. 3. Voucher distribution registers or their equivalent... pilots' flight logs and passenger lists relevant to a determination of the validity of a carrier's...' reports; records of receipts and disbursements including bank statements, check registers and...

  1. 30 CFR 250.249 - What air emissions information must accompany the DPP or DOCD?

    Science.gov (United States)

    2010-07-01

    ... when applicable, nitrogen oxides (NOX), carbon monoxide (CO), and volatile organic compounds (VOC) that....303(d). When MMS requires air quality modeling, you must use the guidelines in Appendix W of 40 CFR... data consistent with the model(s) used. (f) Modeling report. A modeling report or the modeling...

  2. 7 CFR 249.10 - Coupon, market, and CSA program management.

    Science.gov (United States)

    2010-01-01

    ... the Rehabilitation Act of 1973, the Age Discrimination Act of 1975, Department of Agriculture... redeemed only for eligible foods; (iii) Provide eligible foods at or less than the price charged to other... than the price charged to other customers; (iv) Assure that the shareholder receives eligible...

  3. Strategic Forum, Number 249, October 2009. Burma in Strategic Perspective: Renewing Discussion of Options

    Science.gov (United States)

    2009-10-01

    leadership of Burma. Bangkok has urged flex- ibility, understanding, a certain amount of accommodation, and real recognition that the equation of...Thailand’s standing in the region or damage Bangkok’s status and leadership. It is not clear that Bangkok is in a posi- tion to add more to the mix. It is...be able to persuade Burma that its national interest lies in freeing up the economy, mak- ing business law transparent, developing tourism as the

  4. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    NARCIS (Netherlands)

    E.K. Speliotes (Elizabeth); C.J. Willer (Cristen); S.I. Berndt (Sonja); K.L. Monda (Keri); G. Thorleifsson (Gudmar); A.U. Jackson (Anne); H.L. Allen; C.M. Lindgren (Cecilia); J. Luan; R. Mägi (Reedik); J.C. Randall (Joshua); S. Vedantam (Sailaja); T.W. Winkler (Thomas); L. Qi (Lu); T. Workalemahu (Tsegaselassie); I.M. Heid (Iris); V. Steinthorsdottir (Valgerdur); H.M. Stringham (Heather); E. Wheeler (Eleanor); A.R. Wood (Andrew); T. Ferreira (Teresa); R.J. Weyant (Robert); A.V. Segrè (Ayellet); K. Eestrada (Karol); L. Liang (Liming); J. Nemesh (James); J.H. Park; S. Gustafsson (Stefan); T.O. Kilpeläinen (Tuomas); J. Yang (Joanna); N. Bouatia-Naji (Nabila); T. Eesko (Tõnu); M.F. Feitosa (Mary Furlan); Z. Kutalik (Zoltán); M. Mangino (Massimo); S. Raychaudhuri (Soumya); A. Scherag (Andre); A.V. Smith (Albert Vernon); R.P. Welch (Ryan); J.H. Zhao; K.K.H. Aben (Katja); D. Absher (Devin); N. Amin (Najaf); A.L. Dixon (Anna); E. Fisher (Eeva); N.L. Glazer (Nicole); M.E. Goddard (Michael); N.L. Heard-Costa (Nancy); V. Hoesel (Volker); J.J. Hottenga (Jouke Jan); A. Johansson (Åsa); T. Johnson (Toby); S. Ketkar (Shamika); C. Lamina (Claudia); S. Li (Shengxu); M.F. Moffatt (Miriam); R.H. Myers (Richard); N. Narisu (Narisu); J.R.B. Perry (John); M.J. Peters (Marjolein); M. Preuss (Michael); S. Ripatti (Samuli); F. Rivadeneira Ramirez (Fernando); C. Sandholt (Camilla); L.J. Scott (Laura); N. Timpson (Nicholas); J.P. Tyrer (Jonathan); S. van Wingerden (Sophie); C.C. White (Charles); F. Wiklund (Fredrik); C. Barlassina (Christina); D.I. Chasman (Daniel); M.N. Cooper (Matthew); J.O. Jansson; R.W. Lawrence (Robert); N. Pellikka (Niina); I. Prokopenko (Inga); J. Shi (Jianxin); E. Thiering (Eelisabeth); H. Alavere (Helene); M.T.S. Alibrandi (Maria); P. Almgren (Peter); A.M. Arnold (Alice); T. Aspelund (Thor); L.D. Atwood (Larry); B. Balkau (Beverley); A.J. Balmforth (Anthony); A.J. Bennett (Amanda); Y. Ben-Shlomo; R.N. Bergman (Richard); S.M. Bergmann (Sven); H. Biebermann (Heike); A.I.F. Blakemore (Alexandra); T. Boes (Tanja); L.L. Bonnycastle (Lori); S.R. Bornstein (Stefan); M.J. Brown (Morris); T.A. Buchanan (Thomas); F. Busonero; H. Campbell (Harry); F.P. Cappuccio (Francesco); C. Cavalcanti-Proença (Christine); Y.D.I. Chen (Yii-Der Ida); C.-M. Chen (Chih-Mei); P.S. Chines (Peter); R. Clarke; L. Coin (Lachlan); J. Connell (John); I.N.M. Day (Ian); M. den Heijer (Martin); J. Duan (Jubao); S. Eebrahim (Shah); P. Eelliott (Paul); R. Eelosua (Roberto); G. Eeiriksdottir (Gudny); M.R. Eerdos (Micheal); J.G. Eeriksson (Johan); M.F. Facheris (Maurizio); S.B. Felix (Stephan); P. Fischer-Posovszky (Pamela); A.R. Folsom (Aaron); N. Friedrich (Nele); N.B. Freimer (Nelson); M. Fu (Mao); S. Gaget (Stefan); P.V. Gejman (Pablo); E.J. Geus (Eeco); C. Gieger (Christian); A.P. Gjesing (Anette); A. Goel (Anuj); P. Goyette (Philippe); H. Grallert (Harald); J. Gräßler (Jürgen); D. Greenawalt (Danielle); C.J. Groves (Christopher); V. Gudnason (Vilmundur); C. Guiducci (Candace); A.L. Hartikainen; N. Hassanali (Neelam); A.S. Hall (Alistair); A.S. Havulinna (Aki); C. Hayward (Caroline); A.C. Heath (Andrew); C. Hengstenberg (Christian); A.A. Hicks (Andrew); A. Hinney (Anke); A. Hofman (Albert); G. Homuth (Georg); J. Hui (Jennie); W. Igl (Wilmar); C. Iribarren (Carlos); B. Isomaa (Bo); K.B. Jacobs (Kevin); I. Jarick (Ivonne); E. Jewell (Eelizabeth); U. John (Ulrich); T. Jørgensen (Torben); P. Jousilahti (Pekka); A. Jula (Antti); M. Kaakinen (Marika); E. Kajantie (Eero); R.C. Kaplan (Robert); S. Kathiresan (Sekar); J. Kettunen (Johannes); L. Kinnunen (Leena); J.W. Knowles (Joshua); I. Kolcic (Ivana); I.R. König (Inke); S. Koskinen (Seppo); P. Kovacs (Peter); J. Kusisto (Johanna); P. Kraft (Peter); K. Kvaløy (Kirsti); J. Laitinen (Jaana); O. Lantieri (Olivier); C. Lanzani (Chiara); L.J. Launer (Lenore); C. Lecoeur (Cécile); T. Lehtimäki (Terho); G. Lettre (Guillaume); J. Liu (Jianjun); M.L. Lokki; M. Lorentzon (Mattias); R.N. Luben (Robert); B. Ludwig (Barbara); P. Manunta (Paolo); D. Marek (Diana); M. Marre (Michel); N.G. Martin (Nicholas); W.L. McArdle (Wendy); M.I. McCarthy (Mark); B. McKnight (Barbara); T. Meitinger (Thomas); O. Melander (Olle); D. Meyre (David); K. Midthjell (Kristian); G.W. Montgomery (Grant); M.A. Morken (Mario); A.D. Morris (Andrew); R. Mulic (Rosanda); J.S. Ngwa; M. Nelis (Mari); M.J. Neville (Matthew); D.R. Nyholt (Dale); C.J. O'Ddonnell (Christopher); S. O'Rahilly (Stephen); K. Ong (Ken); B.A. Oostra (Ben); G. Paré (Guillaume); A.N. Parker (Alex); M. Perola (Markus); I. Pichler (Irene); K.H. Pietilainen (Kirsi Hannele); C.P. Platou (Carl); O. Polasek (Ozren); A. Pouta (Anneli); S. Rafelt (Suzanne); O. Raitakari (Olli); N.W. Rayner (Nigel William); M. Ridderstråle (Martin); W. Rief (Winfried); A. Ruokonen (Aimo); N.R. Robertson (Neil); P. Rzehak (Peter); V. Salomaa (Veikko); A.R. Sanders (Alan); M.S. Sandhu (Manjinder); S. Sanna (Serena); J. Saramies (Jouko); M.J. Savolainen (Markku); S. Schipf (Sabine); S. Schreiber (Stefan); H. Schunkert (Heribert); K. Silander (Kaisa); J. Sinisalo (Juha); D.S. Siscovick (David); J.H. Smit (Jan); N. Soranzo (Nicole); U. Sovio (Ulla); J. Stephens (Jonathan); I. Surakka (Ida); A.J. Swift (Amy); M.L. Tammesoo; J.-C. Tardif (Jean-Claude); M. Teder-Laving (Maris); T.M. Teslovich (Tanya); J.R. Thompson (John); B. Thomson (Brian); A. Tönjes (Anke); T. Tuomi (Tiinamaija); J.B.J. van Meurs (Joyce); G.J. van OMen; V. Vatin (Vincent); J. Viikari (Jorma); S. Visvikis-Siest (Sophie); V. Vitart (Veronique); C.I. Vogel (Carla); B.F. Voight (Benjamin); L. Waite (Lindsay); H. Wallaschofski (Henri); G.B. Walters (Bragi); E. Widen (Elisabeth); S. Wiegand (Susanna); S.H. Wild (Sarah); G.A.H.M. Willemsen (Gonneke); D.R. Witte (Deniel); J.C.M. Witteman (Jacqueline); J. Xu (Jianfeng); Q. Zhang (Qunyuan); L. Zgaga (Lina); A. Ziegler (Andreas); P. Zitting (Paavo); J.P. Beilby (John); I.S. FarOqi (Ssadaf); J. Hebebrand (Johannes); H.V. Huikuri (Heikki); A. James (Alan); M. Kähönen (Mika); D.F. Levinson (Douglas); F. MacCiardi (Fabio); M.S. Nieminen (Markku); C. Ohlsson (Claes); C. Palmer (Cameron); P.M. Ridker (Paul); M. Stumvoll (Michael); J.S. Beckmann (Jacques); H. Boeing (Heiner); E.A. Boerwinkle (Eric); D.I. Boomsma (Dorret); M. Caulfield (Mark); S.J. Chanock (Stephen); F.S. Collins (Francis); L.A. Cupples (Adrienne); J. Eerdmann (Jeanette); P. Frogue (Philippe); H. Grönberg (Henrik); U. Gyllensten (Ulf); T. Hansen (Torben); T.B. Harris (Tamara); A.T. Hattersley (Andrew); R.B. Hayes (Richard); J. Heinrich (Joachim); F.B. Hu (Frank); K. Hveem (Kristian); T. Illig (Thomas); M.R. Järvelin; J. Kaprio (Jaakko); F. Karpe (Fredrik); K-T. Khaw (Kay-Tee); L.A.L.M. Kiemeney (Bart); H. Krude; M. Laakso (Markku); D.A. Lawlor (Debbie); A. Metspalu (Andres); P. Munroe (Patricia); W.H. Ouwehand (Willem); O. Pedersen (Oluf); B.W.J.H. Penninx (Brenda); P.P. Pramstaller (Peter Paul); T. Quertermous (Thomas); T. Reinehr (Thomas); A. Rissanen (Aila); I. Rudan (Igor); N.J. Samani (Nilesh); P.E.H. Schwarz (Peter); A.R. Shuldiner (Alan); T.D. Spector (Timothy); J. Tuomilehto (Jaakko); M. Uda (Manuela); A.G. Uitterlinden (André); T.T. Valle (Timo); M. Wabitsch (Martin); G. Waeber (Gérard); N.J. Wareham (Nick); H. Watkins (Hugh); J.F. Wilson (James); A.F. Wright (Alan); M.C. Zillikens (Carola); N. ChatterjE (Nilanjan); S.A. McCarroll (Steve); S. Purcell (Shaun); E.E. Schadt (Eric); P.M. Visscher (Peter); T.L. Assimes (Themistocles); I.B. Borecki (Ingrid); P. Deloukas (Panagiotis); C.S. Fox (Caroline); L. Groop (Leif); T. Haritunians (Talin); D.J. Hunter (David); K.L. Mohlke (Karen); J.R. O'ConneL (Jeffrey); L. Peltonen (Leena Johanna); D. SchleSinger (David); D.P. Strachan (David); R.M. Watanabe (Richard); C.M. van Duijn (Cock); H.E. Wichmann (Heinz Erich); T.M. Frayling (Timothy); U. Thorsteinsdottir (Unnur); G.R. Abecasis (Gonçalo); M. Boehnke (Michael); K. StefanSon (Kari); K.E. North (Kari); M.I. McArthy (Mark); J.N. Hirschhorn (Joel); E. IngelSon (Erik); R.J.F. Loos (Ruth); M.N. Weedon (Michael)

    2010-01-01

    textabstractObesity is globaLy prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined aSociations betwEn body maS index and ĝ̂1/42.8 miLion SNPs in up to 123,865 individuals with targeted foLow up of

  5. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    NARCIS (Netherlands)

    Speliotes, Elizabeth K.; Willer, Cristen J.; Berndt, Sonja I.; Monda, Keri L.; Thorleifsson, Gudmar; Jackson, Anne U.; Allen, Hana Lango; Lindgren, Cecilia M.; Luan, Jian'an; Maegi, Reedik; Randall, Joshua C.; Vedantam, Sailaja; Winkler, Thomas W.; Qi, Lu; Workalemahu, Tsegaselassie; Heid, Iris M.; Steinthorsdottir, Valgerdur; Stringham, Heather M.; Weedon, Michael N.; Wheeler, Eleanor; Wood, Andrew R.; Ferreira, Teresa; Weyant, Robert J.; Segre, Ayellet V.; Estrada, Karol; Liang, Liming; Nemesh, James; Park, Ju-Hyun; Gustafsson, Stefan; Kilpelaenen, Tuomas O.; Yang, Jian; Bouatia-Naji, Nabila; Esko, Tonu; Feitosa, Mary F.; Kutalik, Zoltan; Mangino, Massimo; Raychaudhuri, Soumya; Scherag, Andre; Smith, Albert Vernon; Welch, Ryan; Zhao, Jing Hua; Aben, Katja K.; Absher, Devin M.; Amin, Najaf; Dixon, Anna L.; Fisher, Eva; Glazer, Nicole L.; Goddard, Michael E.; Heard-Costa, Nancy L.; Hoesel, Volker; Hottenga, Jouke-Jan; Johansson, Asa; Johnson, Toby; Ketkar, Shamika; Lamina, Claudia; Li, Shengxu; Moffatt, Miriam F.; Myers, Richard H.; Narisu, Narisu; Perry, John R. B.; Peters, Marjolein J.; Preuss, Michael; Ripatti, Samuli; Rivadeneira, Fernando; Sandholt, Camilla; Scott, Laura J.; Timpson, Nicholas J.; Tyrer, Jonathan P.; van Wingerden, Sophie; Watanabe, Richard M.; White, Charles C.; Wiklund, Fredrik; Barlassina, Christina; Chasman, Daniel I.; Cooper, Matthew N.; Jansson, John-Olov; Lawrence, Robert W.; Pellikka, Niina; Prokopenko, Inga; Shi, Jianxin; Thiering, Elisabeth; Alavere, Helene; Alibrandi, Maria T. S.; Almgren, Peter; Arnold, Alice M.; Aspelund, Thor; Atwood, Larry D.; Balkau, Beverley; Balmforth, Anthony J.; Bennett, Amanda J.; Ben-Shlomo, Yoav; Bergman, Richard N.; Bergmann, Sven; Biebermann, Heike; Blakemore, Alexandra I. F.; Boes, Tanja; Bonnycastle, Lori L.; Bornstein, Stefan R.; Brown, Morris J.; Buchanan, Thomas A.; Busonero, Fabio; Campbell, Harry; Cappuccio, Francesco P.; Cavalcanti-Proenca, Christine; Chen, Yii-Der Ida; Chen, Chih-Mei; Chines, Peter S.; Clarke, Robert; Coin, Lachlan; Connell, John; Day, Ian N. M.; den Heijer, Martin; Duan, Jubao; Ebrahim, Shah; Elliott, Paul; Elosua, Roberto; Eiriksdottir, Gudny; Erdos, Michael R.; Eriksson, Johan G.; Facheris, Maurizio F.; Felix, Stephan B.; Fischer-Posovszky, Pamela; Folsom, Aaron R.; Friedrich, Nele; Freimer, Nelson B.; Fu, Mao; Gaget, Stefan; Gejman, Pablo V.; Geus, Eco J. C.; Gieger, Christian; Gjesing, Anette P.; Goel, Anuj; Goyette, Philippe; Grallert, Harald; Graessler, Juergen; Greenawalt, Danielle M.; Groves, Christopher J.; Gudnason, Vilmundur; Guiducci, Candace; Hartikainen, Anna-Liisa; Hassanali, Neelam; Hall, Alistair S.; Havulinna, Aki S.; Hayward, Caroline; Heath, Andrew C.; Hengstenberg, Christian; Hicks, Andrew A.; Hinney, Anke; Hofman, Albert; Homuth, Georg; Hui, Jennie; Igl, Wilmar; Iribarren, Carlos; Isomaa, Bo; Jacobs, Kevin B.; Jarick, Ivonne; Jewell, Elizabeth; John, Ulrich; Jorgensen, Torben; Jousilahti, Pekka; Jula, Antti; Kaakinen, Marika; Kajantie, Eero; Kaplan, Lee M.; Kathiresan, Sekar; Kettunen, Johannes; Kinnunen, Leena; Knowles, Joshua W.; Kolcic, Ivana; Koenig, Inke R.; Koskinen, Seppo; Kovacs, Peter; Kuusisto, Johanna; Kraft, Peter; Kvaloy, Kirsti; Laitinen, Jaana; Lantieri, Olivier; Lanzani, Chiara; Launer, Lenore J.; Lecoeur, Cecile; Lehtimaeki, Terho; Lettre, Guillaume; Liu, Jianjun; Lokki, Marja-Liisa; Lorentzon, Mattias; Luben, Robert N.; Ludwig, Barbara; Manunta, Paolo; Marek, Diana; Marre, Michel; Martin, Nicholas G.; McArdle, Wendy L.; McCarthy, Anne; McKnight, Barbara; Meitinger, Thomas; Melander, Olle; Meyre, David; Midthjell, Kristian; Montgomery, Grant W.; Morken, Mario A.; Morris, Andrew P.; Mulic, Rosanda; Ngwa, Julius S.; Nelis, Mari; Neville, Matt J.; Nyholt, Dale R.; O'Donnell, Christopher J.; O'Rahilly, Stephen; Ong, Ken K.; Oostra, Ben; Pare, Guillaume; Parker, Alex N.; Perola, Markus; Pichler, Irene; Pietilaeinen, Kirsi H.; Platou, Carl G. P.; Polasek, Ozren; Pouta, Anneli; Rafelt, Suzanne; Raitakari, Olli; Rayner, Nigel W.; Ridderstrale, Martin; Rief, Winfried; Ruokonen, Aimo; Robertson, Neil R.; Rzehak, Peter; Salomaa, Veikko; Sanders, Alan R.; Sandhu, Manjinder S.; Sanna, Serena; Saramies, Jouko; Savolainen, Markku J.; Scherag, Susann; Schipf, Sabine; Schreiber, Stefan; Schunkert, Heribert; Silander, Kaisa; Sinisalo, Juha; Siscovick, David S.; Smit, Jan H.; Soranzo, Nicole; Sovio, Ulla; Stephens, Jonathan; Surakka, Ida; Swift, Amy J.; Tammesoo, Mari-Liis; Tardif, Jean-Claude; Teder-Laving, Maris; Teslovich, Tanya M.; Thompson, John R.; Thomson, Brian; Toenjes, Anke; Tuomi, Tiinamaija; van Meurs, Joyce B. J.; van Ommen, Gert-Jan; Vatin, Vincent; Viikari, Jorma; Visvikis-Siest, Sophie; Vitart, Veronique; Vogel, Carla I. G.; Voight, Benjamin F.; Waite, Lindsay L.; Wallaschofski, Henri; Walters, G. Bragi; Widen, Elisabeth; Wiegand, Susanna; Wild, Sarah H.; Willemsen, Gonneke; Witte, Daniel R.; Witteman, Jacqueline C.; Xu, Jianfeng; Zhang, Qunyuan; Zgaga, Lina; Ziegler, Andreas; Zitting, Paavo; Beilby, John P.; Farooqi, I. Sadaf; Hebebrand, Johannes; Huikuri, Heikki V.; James, Alan L.; Kaehoenen, Mika; Levinson, Douglas F.; Macciardi, Fabio; Nieminen, Markku S.; Ohlsson, Claes; Palmer, Lyle J.; Ridker, Paul M.; Stumvoll, Michael; Beckmann, Jacques S.; Boeing, Heiner; Boerwinkle, Eric; Boomsma, Dorret I.; Caulfield, Mark J.; Chanock, Stephen J.; Collins, Francis S.; Cupples, L. Adrienne; Smith, George Davey; Erdmann, Jeanette; Froguel, Philippe; Greonberg, Henrik; Gyllensten, Ulf; Hall, Per; Hansen, Torben; Harris, Tamara B.; Hattersley, Andrew T.; Hayes, Richard B.; Heinrich, Joachim; Hu, Frank B.; Hveem, Kristian; Illig, Thomas; Jarvelin, Marjo-Riitta; Kaprio, Jaakko; Karpe, Fredrik; Khaw, Kay-Tee; Kiemeney, Lambertus A.; Krude, Heiko; Laakso, Markku; Lawlor, Debbie A.; Metspalu, Andres; Munroe, Patricia B.; Ouwehand, Willem H.; Pedersen, Oluf; Penninx, Brenda W.; Peters, Annette; Pramstaller, Peter P.; Quertermous, Thomas; Reinehr, Thomas; Rissanen, Aila; Rudan, Igor; Samani, Nilesh J.; Schwarz, Peter E. H.; Shuldiner, Alan R.; Spector, Timothy D.; Tuomilehto, Jaakko; Uda, Manuela; Uitterlinden, Andre; Valle, Timo T.; Wabitsch, Martin; Waeber, Gerard; Wareham, Nicholas J.; Watkins, Hugh; Wilson, James F.; Wright, Alan F.; Zillikens, M. Carola; Chatterjee, Nilanjan; McCarroll, Steven A.; Purcell, Shaun; Schadt, Eric E.; Visscher, Peter M.; Assimes, Themistocles L.; Borecki, Ingrid B.; Deloukas, Panos; Fox, Caroline S.; Groop, Leif C.; Haritunians, Talin; Hunter, David J.; Kaplan, Robert C.; Mohlke, Karen L.; O'Connell, Jeffrey R.; Peltonen, Leena; Schlessinger, David; Strachan, David P.; van Duijn, Cornelia M.; Wichmann, H-Erich; Frayling, Timothy M.; Thorsteinsdottir, Unnur; Abecasis, Goncalo R.; Barroso, Ines; Boehnke, Michael; Stefansson, Kari; North, Kari E.; McCarthy, Mark I.; Hirschhorn, Joel N.; Ingelsson, Erik; Loos, Ruth J. F.

    2010-01-01

    Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and similar to 2.8 million SNPs in up to 123,865 individuals with targeted follow up of

  6. Missing and Abducted Children: The School's Role in Prevention. Fastback 249.

    Science.gov (United States)

    Wishon, Phillip M.; Broderius, Bruce W.

    The purpose of this pamphlet is to aid teachers, counselors, administrators, paraprofessionals, and other support personnel in alleviating the problem of missing and abducted children. After an introductory overview of the national incidence of missing children, three specific categories of missing children are identified and discussed: runaways,…

  7. Foreign Investment in the U.S.: Costs and Benefits. Headline Series 249.

    Science.gov (United States)

    Zupnick, Elliot

    The document discusses the implications and positive and negative aspects of foreign direct investment in the United States. The objective is to determine whether a restrictive U.S. policy as it relates to foreign direct investment in the United States is desirable. It is presented in five chapters. Chapter I defines foreign direct investment…

  8. 7 CFR 249.8 - Level of benefits and eligible foods.

    Science.gov (United States)

    2010-01-01

    ..., such as prunes (dried plums), raisins (dried grapes), sun-dried tomatoes, or dried chili peppers are..., wild rice, nuts of any kind (even raw), maple syrup, cider, seeds, eggs, meat, cheese, and seafood...

  9. Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and tri-n-octylphosphine oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hannink, N.J.; Hoffman, D.C. [Lawrence Berkeley Lab., CA (United States)]|[California Univ., Berkeley, CA (United States). Dept. of Chemistry; Smith, B.F. [Los Alamos National Lab., NM (United States)

    1991-11-01

    The first measurements of distribution coefficients (K{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}`s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}`s for these actinides are about a factor of 5 to 10 greater than the K{sub d}`s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}`s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand.

  10. Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and tri-n-octylphosphine oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hannink, N.J.; Hoffman, D.C. (Lawrence Berkeley Lab., CA (United States) California Univ., Berkeley, CA (United States). Dept. of Chemistry); Smith, B.F. (Los Alamos National Lab., NM (United States))

    1991-11-01

    The first measurements of distribution coefficients (K{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}'s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}'s for these actinides are about a factor of 5 to 10 greater than the K{sub d}'s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}'s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand.

  11. Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and Tri-n-octylphosphine oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hannink, N.J.; Hoffman, D.C. [Lawrence Berkeley Lab., CA (United States); Smith, B.F. [Los Alamos National Lab., NM (United States)

    1992-07-01

    The first measurements of distribution coefficients (k{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}`s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}`s for these actinides are about about a factor of 10 greater than the K{sub d}`s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}`s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand. 9 refs., 2 figs., 1 tab.

  12. 249株流感嗜血杆菌的分离与耐药性分析%Analysis on Isolation and Antibiotic Resistance of 249 Strains of Haemophilus influenzae

    Institute of Scientific and Technical Information of China (English)

    曹敏晖; 曹友德; 李浩; 蔡瑞云

    2011-01-01

    目的 了解流感嗜血杆菌(Hi)的检出状况与耐药情况,指导临床合理用药.方法 统计分析2007-2010年我院Hi的分离与耐药情况.结果 在1052份痰及咽拭子标本中分离出Hi 210株,在242份胆汁标本中分离出Hi 16株,在203份胸腹水标本中分离出Hi 12株,在163份眼、耳拭子标本中分离出Hi 11株.体外药敏结果显示Hi对复方磺胺甲恶哇耐药性最高为63.5%,氨苄西林次之为46.2%,而对阿莫西林/棒酸、利福平、头孢呋辛、头孢噻肟、亚氨培南敏感,耐药率≤2.0%.结论 Hi在呼吸道标本中的检出率最高,眼、耳拭子标本中次之,在胆汁、胸腹水中亦有检出.建议眼、耳拭子及胆汁、胸腹水标本作细菌培养时也应同时接种哥伦比亚血平板(COS)、淋球菌选择性平板(VCA)及嗜血杆菌选择性平板(HAE),Hi感染的治疗应首选复方阿莫西林、头孢二代或三代类抗生素.%Objective To investigate the isolation rate and antibiotic resistance rate of Haemophilus influenzae, and to guide the rational use of antibiotic therapy in clinical practice. Methods The data about the isolation rate and antibiotic resistance rate of Haemophilus influenzae from 2007 to 2010 were analyzed with SPSS11.0 statistical software. Results Totally 210 strains of Haemophilus influenzae were isolated from 1,052 specimens of sputum and pharyngeal secretion, 16 strains isolated from 242 bile specimens, 12 strains isolated from 203 hydrothoraxs specimens, and 11 strains isolated from 163 specimens of eye or ear secretion. In vitro drug- sensitivity test showed that the resistance rate of Haemophilus influenzae to trimethoprime sulfanomicles was the highest (63.5%), followed by ampicillin (46.2%). But the resistance rates to amoxicillin/clavalanic acid, rifampicine, cefuroxime, cefotaxime and imipenem were very low (≤2.0%). Conclusions Heamophilus influenzae could be isolated from the secretions of respiratory track, eye, ear, bile, and hydrothoraxs. It is necessary that using COS, VCA f- lat, and HAE while performing bacterial culture of the secretions of eye, ear, bile, and hydrothoraxs. The therapy of Heamophilus influenzae infection should choose the antibiotics, such as amoxicillin/ clavalanic acid, cefuroxime and cefotaxime.

  13. 75 FR 19880 - Safety Zone; BW PIONEER at Walker Ridge 249, Outer Continental Shelf FPSO, Gulf of Mexico

    Science.gov (United States)

    2010-04-16

    ... available online by going to http://www.regulations.gov , inserting USCG-2009-0571 in the ``Keyword'' box... District, IMO guidelines, and existing regulations. The FPSO can swing in a 360 degree arc around the... hull of the vessel. It will attach to a moored turret buoy and move in a 360 degree arc around...

  14. 17 CFR 240.15d-13 - Quarterly reports on Form 10-Q (§ 249.308 of this chapter).

    Science.gov (United States)

    2010-04-01

    ... pursuant to § 240.15d-16; and (3) Asset-backed issuers required to file reports pursuant to § 240.15d-17... the development of mineral deposits other than oil, gas or coal, if all of the following...

  15. Metabolic products of microorganisms. 249. Tetracenomycins B3 and D3, key intermediates of the elloramycin and tetracenomycin C biosynthesis.

    Science.gov (United States)

    Rohr, J; Eick, S; Zeeck, A; Reuschenbach, P; Zähner, H; Fiedler, H P

    1988-08-01

    Tetracenomycins B3 and D3, besides tetracenomycin D (D1), were produced by a blocked mutant of the elloramycin producer Streptomyces olivaceus TU 2353. The compounds were isolated as red powders, and their structures were elucidated by comparing their physicochemical data with those of the known tetracenomycins A2, B1, B2, D and E. Tetracenomycin B3 (2), the main compound, and tetracenomycin D (3) were antibiotically inactive against Gram-positive and Gram-negative bacteria, whereas tetracenomycin D3 (1) showed a moderate activity against Bacillus subtilis and Arthrobacter aurescens. Tetracenomycin B3 (2) is the key intermediate where the biosynthesis of the elloramycins branches off from the line leading to tetracenomycin C (5) as the final product of the tetracenomycin biosynthesis branch.

  16. SU-E-T-249: Neutron Model Upgrade for Radiotherapy Patients Monitoring Using a New Online Detector

    Energy Technology Data Exchange (ETDEWEB)

    Irazola, L; Sanchez Doblado, F. [Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla (Spain); Servicio de Radiofisica, Hospital Universitario Virgen Macarena, Sevilla (Spain); Lorenzoli, M; Pola, A. [Politecnico di Milano, Departimento di Ingegneria Nuclear, Milano (Italy); Terron, J.A. [Servicio de Radiofisica, Hospital Universitario Virgen Macarena, Sevilla (Spain); Bedogni, R. [Laboratori Nazionali di Frascati, Istituto Nazionale di Fisica Nucleare (INFN) (Italy); Sanchez Nieto, B. [Instituto de Fisica, Pontificia Universidad Catolica de Chile, Santiago (Chile); Romero-Exposito, M. [Departamento de Fisica, Universitat Autonoma de Barcelona (Spain)

    2014-06-01

    Purpose: The purpose of this work is to improve the existing methodology to estimate neutron equivalent dose in organs during radiotherapy treatments, based on a Static Random Access Memory neutron detector (SRAMnd) [1]. This is possible thanks to the introduction of a new digital detector with improved characteristics, which is able to measure online the neutron fluence rate in the presence of an intense photon background [2]. Its reduced size, allows the direct estimation of doses in specific points inside an anthropomorphic phantom (NORMA) without using passive detectors as TLD or CR-39. This versatility will allow not only to improve the existing models (generic abdomen and H and N [1]) but to generate more specific ones for any technique. Methods: The new Thermal Neutron Rate Detector (TNRD), based on a diode device sensitized to thermal neutrons, have been inserted in 16 points of the phantom. These points are distributed to infer doses to specific organs. Simultaneous measurements of these devices and a reference one, located in front of the gantry, have been performed for the mentioned generic treatments, in order to improve the existing model. Results: These new devices have shown more precise since they agree better with Monte Carlo simulations. The comparison of the thermal neutron fluence, measured with TNRD, and the existing models, converted from events to fluence, shows an average improvement of (3.90±3.37) % for H and N and (12.61±9.43) % for abdomen, normalized to the maximum value. Conclusion: This work indicates the potential of these new devices for more precise neutron equivalent dose estimation in organs, as a consequence of radiotherapy treatments. The simplicity of the process makes possible to establish more specific models that will provide a better dose estimation. References[1] Phys Med Biol 2012; 57:6167–6191.[2] A new active thermal neutron detector. Radiat. Prot. Dosim. (in press)

  17. Sacchi, Livio (2004. Tokyo: City and Architecture. 249 p. ISBN: 0-7893-1212-3. Nueva York: Universe Publishing.

    Directory of Open Access Journals (Sweden)

    Fermin Ernesto Flores Quiroz

    2016-12-01

    Full Text Available The book by the Italian author Livio Sacchi, focuses on the analysis on the spatial development of the city of Tokyo and the way in which the socioeconomic processes of the 19th and 20th centuries influenced the conformation of the urban structure on which millions of Tokyo citizens develop their daily life. During the text, the author underlines the impact of the modern architectural movement on the urban landscape of Tokyo. Furthermore, it is important to mention that this work serves as a translator for the western readers, because it deciphers the social and spatial characteristics that constitute the most populous city in the world.

  18. Actinide Production in the Reaction of Heavy Ions withCurium-248

    Energy Technology Data Exchange (ETDEWEB)

    Moody, K.J.

    1983-07-01

    Chemical experiments were performed to examine the usefulness of heavy ion transfer reactions in producing new, neutron-rich actinide nuclides. A general quasi-elastic to deep-inelastic mechanism is proposed, and the utility of this method as opposed to other methods (e.g. complete fusion) is discussed. The relative merits of various techniques of actinide target synthesis are discussed. A description is given of a target system designed to remove the large amounts of heat generated by the passage of a heavy ion beam through matter, thereby maximizing the beam intensity which can be safely used in an experiment. Also described is a general separation scheme for the actinide elements from protactinium (Z = 91) to mendelevium (Z = 101), and fast specific procedures for plutonium, americium and berkelium. The cross sections for the production of several nuclides from the bombardment of {sup 248}Cm with {sup 18}O, {sup 86}Kr and {sup 136}Xe projectiles at several energies near and below the Coulomb barrier were determined. The results are compared with yields from {sup 48}Ca and {sup 238}U bombardments of {sup 248}Cm. Simple extrapolation of the product yields into unknown regions of charge and mass indicates that the use of heavy ion transfer reactions to produce new, neutron-rich above-target species is limited. The substantial production of neutron-rich below-target species, however, indicates that with very heavy ions like {sup 136}Xe and {sup 238}U the new species {sup 248}Am, {sup 249}Am and {sup 247}Pu should be produced with large cross sections from a {sup 248}Cm target. A preliminary, unsuccessful attempt to isolate {sup 247}Pu is outlined. The failure is probably due to the half life of the decay, which is calculated to be less than 3 minutes. The absolute gamma ray intensities from {sup 251}Bk decay, necessary for calculating the {sup 251}Bk cross section, are also determined.

  19. 17 CFR 240.13a-13 - Quarterly reports on Form 10-Q (§ 249.308a of this chapter).

    Science.gov (United States)

    2010-04-01

    ...; and (3) Asset-backed issuers required to file reports pursuant to § 240.13a-17. (c) Part I of the... mineral deposits other than oil, gas or coal, if all of the following conditions are met: (i)...

  20. 33 CFR 207.249 - Ouachita and Black Rivers, Ark. and La., Mile 0.0 to Mile 338.0 (Camden, Ark.) above the mouth of...

    Science.gov (United States)

    2010-07-01

    ... other lockages, then separate lockages shall be made. Dangerous cargoes are described in 46 CFR part 146... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Ouachita and Black Rivers, Ark. and La., Mile 0.0 to Mile 338.0 (Camden, Ark.) above the mouth of the Black River; the Red River,...

  1. SU-E-J-249: Characterization of Gynecological Tumor Heterogeneity Using Texture Analysis in the Context of An 18F-FDG PET Adaptive Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Nawrocki, J [Duke University Medical Physics Graduate Program, Durham, NC (United States); Chino, J; Craciunescu, O [Duke University Medical Center Department of Radiation Oncology, Durham, NC (United States); Das, S [University of North Carolina School of Medicine, Chapel Hill, NC (United States)

    2015-06-15

    Purpose: We propose a method to examine gynecological tumor heterogeneity using texture analysis in the context of an adaptive PET protocol in order to establish if texture metrics from baseline PET-CT predict tumor response better than SUV metrics alone as well as determine texture features correlating with tumor response during radiation therapy. Methods: This IRB approved protocol included 29 women with node positive gynecological cancers visible on FDG-PET treated with EBRT to the PET positive nodes. A baseline and intra-treatment PET-CT was obtained. Tumor outcome was determined based on RECIST on posttreatment PET-CT. Primary GTVs were segmented using 40% threshold and a semi-automatic gradient-based contouring tool, PET Edge (MIM Software Inc., Cleveland, OH). SUV histogram features, Metabolic Volume (MV), and Total Lesion Glycolysis (TLG) were calculated. Four 3D texture matrices describing local and regional relationships between voxel intensities in the GTV were generated: co-occurrence, run length, size zone, and neighborhood difference. From these, 39 texture features were calculated. Prognostic power of baseline features derived from gradientbased and threshold GTVs were determined using the Wilcoxon rank-sum test. Receiver Operating Characteristics and logistic regression was performed using JMP (SAS Institute Inc., Cary, NC) to find probabilities of predicting response. Changes in features during treatment were determined using the Wilcoxon signed-rank test. Results: Of the 29 patients, there were 16 complete responders, 7 partial responders, and 6 non-responders. Comparing CR/PR vs. NR for gradient-based GTVs, 7 texture values, TLG, and SUV kurtosis had a p < 0.05. Threshold GTVs yielded 4 texture features and TLG with p < 0.05. From baseline to intra-treatment, 14 texture features, SUVmean, SUVmax, MV, and TLG changed with p < 0.05. Conclusion: Texture analysis of PET imaged gynecological tumors is an effective method for early prognosis and should be used complimentary to SUV metrics, especially when using gradient based segmentation.

  2. RRS Discovery Cruise 249, 19 Aug-10 Sep 2000. History of sedimentation in the Gulf of Cadiz: investigations with the SOC giant piston corer

    OpenAIRE

    Weaver, P.P.E.

    2003-01-01

    This was the third cruise using the new SOC giant piston corer. The objectives were to complete the testing of the giant piston corer which was begun on cruise D219 in November/December 1995 and cruise D225 in February/March 1997, and to collect giant piston cores from the Gulf of Cadiz on sites selected from the TOBI survey carried out on cruise D244 in December 1999. As on previous cruises we had problems with both the ships equipment (outboard sheave on coring gantry), and the giant pist...

  3. Characterization of the in vitro expressed autoimmune rippling muscle disease immunogenic domain of human titin encoded by TTN exons 248-249

    Energy Technology Data Exchange (ETDEWEB)

    Zelinka, L. [Biomedical Sciences Program, Kent State University, Kent, OH (United States); McCann, S.; Budde, J.; Sethi, S.; Guidos, M.; Giles, R. [Center for Applied Chemical Biology, Department of Biological Sciences, Youngstown State University, One University Plaza, Youngstown, OH 44555 (United States); Walker, G.R., E-mail: grwalker@ysu.edu [Center for Applied Chemical Biology, Department of Biological Sciences, Youngstown State University, One University Plaza, Youngstown, OH 44555 (United States); Biomedical Sciences Program, Kent State University, Kent, OH (United States)

    2011-08-05

    Highlights: {yields} Affinity purification of the autoimmune rippling muscle disease immunogenic domain of titin. {yields} Partial sequence analysis confirms that the peptides is in the I band region of titin. {yields} This region of the human titin shows high degree of homology to mouse titin N2-A. -- Abstract: Autoimmune rippling muscle disease (ARMD) is an autoimmune neuromuscular disease associated with myasthenia gravis (MG). Past studies in our laboratory recognized a very high molecular weight skeletal muscle protein antigen identified by ARMD patient antisera as the titin isoform. These past studies used antisera from ARMD and MG patients as probes to screen a human skeletal muscle cDNA library and several pBluescript clones revealed supporting expression of immunoreactive peptides. This study characterizes the products of subcloning the titin immunoreactive domain into pGEX-3X and the subsequent fusion protein. Sequence analysis of the fusion gene indicates the cloned titin domain (GenBank ID: (EU428784)) is in frame and is derived from a sequence of N2-A spanning the exons 248-250 an area that encodes the fibronectin III domain. PCR and EcoR1 restriction mapping studies have demonstrated that the inserted cDNA is of a size that is predicted by bioinformatics analysis of the subclone. Expression of the fusion protein result in the isolation of a polypeptide of 52 kDa consistent with the predicted inferred amino acid sequence. Immunoblot experiments of the fusion protein, using rippling muscle/myasthenia gravis antisera, demonstrate that only the titin domain is immunoreactive.

  4. 17 CFR 249.820 - Form 19b-4(e) for the listing and trading of new derivative securities products by self...

    Science.gov (United States)

    2010-04-01

    ... and trading of new derivative securities products by self-regulatory organizations that are not deemed... listing and trading of new derivative securities products by self-regulatory organizations that are not... self-regulatory organization's listing and trading of a new derivative securities product that is...

  5. 17 CFR 249.220f - Form 20-F, registration of securities of foreign private issuers pursuant to section 12(b) or (g...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form 20-F, registration of securities of foreign private issuers pursuant to section 12(b) or (g), annual and transition reports...-F, registration of securities of foreign private issuers pursuant to section 12(b) or (g),...

  6. Book Review: Philosophy and geometry: theoretical and historical issues. Lorenzo Magnani, Kluwer Academic Publishers, Dordrecht, 2001, pp. xix + 249, US 88. ISBN 0-792-36933-5

    Science.gov (United States)

    Torretti, Roberto

    The best philosophers have been fascinated with geometry ever since the inception of both traditions in 5th century Greece. They have perceived the apparent certainty of geometrical propositions as an intimation that an equally secure knowledge can be had on a subject of the greatest practical concern, viz., the principles of morals. They also have sought to find-as is their wont-reasons for that certainty. This search has given rise to the theoretical and historical issues magisterially reviewed in this book by Lorenzo Magnani. He focuses his attention especially on Kant (Chapters 2 and 3), Poincaré (Chapter 5) and Husserl (Chapter 7.2), and on their original and importantly different ways of explaining the true nature and source of geometrical truth. Despite their diversity, all three can be said to share a trait that is rarely emphasized and which Magnani brings out in full force in his study of Kant. Chapter 2 is called "Geometry: the Model of Knowledge", and his detailed and very able presentation of Kant's philosophy of geometry in this chapter and the next stresses the paradigmatic role of geometrical knowledge in Kant's conception of science. This role is even clearer in the case of Poincaré, whose conventionalism was rooted in his view of geometry but was eventually extended to all the foundations of physics. An enterprising scholar might even try to make a similar point with regard to Husserl, whose views on the establishment of objectivity and science appear to fit geometry better than any other branch of knowledge.

  7. Evidence for association of D1S249 locus on human chromosome 1 with the susceptibility to essential hypertension in Han Chinese

    Institute of Scientific and Technical Information of China (English)

    ZHENG; Yong; (

    2001-01-01

    [1]Jeunemaitre, X., Soubrier, F., Kotelevtsev, Y. V. et al., Molecular basis of hypertension: role of angiotensinogen, Cell, 1993, 71: 169.[2]Hingorani, A. D., Sharma, P., Jia, H. et al., Blood pressure and M235T polymorphism of the angiotensinogen gene, Hypertension, 1996, 28: 907.[3]Liu, Y., Zhou, W. Y., Qiu, C. C. et al., Association analysis of polymorphisms of ACE gene and AGT gene with essential hypertension in Chinese Han's population, Chin. Med. Sci. J., 1998, 13(2): 71.[4]Davies, E., Bonnar, D. A., Lathrop, G. M. et al., Human angiotensin II type I receptor locus, CA repeat polymorphism and genetic mapping, Hum. Mol. Genet., 1994, 3: 838.[5]Kainulainen, K., Perola, M., Terwilliger, J. et al., Evidence for involvement of the type I angiotensin II receptor locus in essential hypertension, Hypertension, 1999, 33: 844.[6]Wang, W. Y. S., Zee, R. Y. L., Morris, B. J. et al., Association of angiotensin II type I receptor gene polymorphism with essential hypertension, Clin. Genet., 1997, 51: 31.[7]Mastana, S., Nunn, J., Angiotensin-converting enzyme deletion polymorphism is associated with hypertension in a sikh population, Human Hered., 1997, 47: 250.[8]Poirier, O., Georges, J. L., Ricard, S. et al., New polymorphisms of the angiotensin II type I receptor gene and their associations with myocardial infarction and blood pressure: the ECTIM study, J. of Hypertension, 1998, 16: 1443.[9]Liu, Y., Qiu, C. C., Zhou, W. Y. et al., Gene polymorphisms of the renin-angiotensin system in essential hypertension, Chinese Medical Journal, 1999, 112(2): 115.[10] Todd, J. A., Genetic analysis of type I diabetes using whole genome approaches, Proc. Natl. Acad. Sci. USA, 1995, 92: 8560.[11] Hanis, C. L., Boerwinkle, E., Chakraborty, R. et al., A genome-wide search for human non-insulin-dependent (type II) diabetes genes reveals a major susceptibility locus on chromosome 2, Nature Genetics, 1996, 13: 161.[12] Hager, J., Dina, C., Franke, S. et al., A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10, Nature Genetics, 1998, 20: 304.[13] Schuster, H., Wienker, T. F., Bahring, S. et al., Severe autosomal dominant hypertension and brachydactyly in a unique Turkish Kindred maps to human chromosome 12, Nature Genetics, 1996, 13: 98.[14] Baima, J., Nicolaou, M., Schwartz, F. et al., Evidence for linkage between essential hypertension and a putative locus on human chromosome 17, Hypertension, 1999, 34: 4.[15] Wright, F. A., O'connor, D. T., Roberts, E. et al., Genome scan for blood pressure loci in mice, Hypertension, 1999, 34: 625.[16] Cox, N. J., Baker, L., Spielman, R. S., Insulin-gene sharing in sib pairs with insulin dependent diabetes mellitus: no evidence for linkage, Am. J. Hum. Genet., 1988, 42: 167.[17] Bonnardeaux, A., Davies, E., Jeunemaitre, X. et al., Angiotensin II type I receptor gene polymorphisms in human essential hypertension, Hypertension, 1994, 24: 63.

  8. 249例细胞学、HPV-DNA分型检测在宫颈癌初筛中的意义分析%Analysis on significances of cytology and HPV-DNA genotyping in primary screening of 249 cases with cervical cancer

    Institute of Scientific and Technical Information of China (English)

    林莉; 林清平; 陈小苑; 徐朝斌

    2013-01-01

    Objective:To analyze and understand the significances of cytology and HPV-DNA genotyping in primary screening of cervical cancer by conducting cytology test,HPV-DNA genotyping,and biopsy among patients from the hospital from August 10th,2010 to October 1 st,2011.Methods:Cytological screening:all the patients were detected by liquid-based Thin Prep cytology test (TCT) ; the diagnostic criterion of TCT was TBS classification; HPV-DNA genotyping:cervical canal samples of all the patients were collected by sampling kit of dot blot,supervising technicians conducted dot blot and analyzed the results,21 kinds of cancer type HPV DNA currently known were detected,including 13 high risk HPV types and 8 low risk and common HPV subtype.All the women underwent electronic colposcopy (SLC-2000,Shenzhen),the operation was conducted by specialized obstetricians and gynecologists,and suspicious lesions underwent colposcopic localization and biopsy.Results:The total sensitivity of joint detection of cytological test and HPV-DNA genotyping was 91.82%,which was significantly higher than those of simple cytological test and simple HPV-DNA genotyping,especially for cervical intraepithelial neoplasia Ⅱ or above lesions,the sensitivity was as high as 100.00%,so joint detection of cytological test and HPV-DNA genotyping was the most reliable method for screening of cervical cancer,which could reduce the missed diagnostic rate to a minimal level.Conclusion:Cytological test is the most reliable method for primary screening of cervical cancer currently,HPV-DNA genotyping only can assist cytological test for primary screening,but it cant replace cytological test completely.HPV-DNA genotyping is a best method for treatment of ASCUS,which can isolate high risk population of ASCUS effectively.Compared with simple cytological test,the sensitivity of joint detection of cytological test and HPV-DNA genotyping increases,but the screening cost increases greatly,it is recommended to use the method in economically developed areas.%目的:通过对在2010年8月10日~2011年10月1日期间厦门市第二医院有做细胞学、HPV-DNA分型和活检的患者分析了解细胞学、HPV-DNA分型检测在宫颈癌初筛中意义.方法:细胞学筛查:所有进入研究的患者均采用泰普生物科学(中国)有限公司的薄层液基细胞学技术(TCT)产品进行检测.细胞学诊断标准采用TBS分类法.HPV-DNA分型检测:所有进入研究的患者用凯普公司点杂交的采样工具包从宫颈管采集标本,并由主管技师进行点杂交检测操作并做出分析,检测目前已知的21种致癌型HPV DNA(即13种高危HPV及8种低危和中国人常见亚型HPV).所有进入研究的妇女使用深圳金科威公司的SLC-2000型电子阴道镜,并由专门的妇产科医师进行检查操作,对可疑病灶进行镜下定位活检.结果:细胞学与HPV-DNA分型检测联合筛查总敏感度是91.82%,均高于2种方法单独检测时的敏感度,尤其是CIN2及以上的病变敏感度高达100.00%,因此细胞学与HPV-DNA分型检测联合筛查,是最稳妥的宫颈癌筛查方案,可以把漏诊率降到最低.结论:细胞学目前还是最可靠的宫颈癌初筛方法,HPV-DNA分型检测只能辅助细胞学进行初筛,还不能完全取代它.对于细胞学ASCUS的处理,HPV-DNA分型检测是最好的一个办法,可以有效地分离出ASCUS中高危人群.细胞学与HPV-DNA分型检测联合筛查与单独做细胞学相比敏感性有所提高,但是筛查成本大大增加,建议在经济较发达的地区使用这一种方法.

  9. Protein (Viridiplantae): 359495301 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available D: LOW QUALITY PROTEIN: valencene synthase Vitis vinifera MELPKLLHSYFPSQFSKXSVLLPFQKINMSGQVLASPLGQFPELENRPVV...24:4279 3398:4279 71240:1195 91827:1195 71275:2879 91834:249 403667:249 3602:249 3603:249 29760:249 PREDICTE

  10. Protein (Viridiplantae): 359495295 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available D: LOW QUALITY PROTEIN: valencene synthase Vitis vinifera MSTQVSASSLAQIPKPKNRPVANYHPNIWGDQFISYIPEDKVTRACKEEQ...24:4279 3398:4279 71240:1195 91827:1195 71275:2879 91834:249 403667:249 3602:249 3603:249 29760:249 PREDICTE

  11. Discovery of Isotopes of the Transuranium Elements with 93 <= Z <= 98

    CERN Document Server

    Fry, C

    2012-01-01

    One hundred and five isotopes of the transuranium elements neptunium, plutonium, americium, curium, berkelium and californium have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  12. RESGPSPNTS_JD249.SHP: Navigation and Bathymetry Points of Ship Position During Continuous Resistivity Profile Data Collection in the Potomac River/Chesapeake Bay on Sept. 6, 2006 on USGS Cruise 06018

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — In order to test hypotheses about groundwater flow under and into Chesapeake Bay, geophysical surveys were conducted by U.S. Geological Survey (USGS) scientists on...

  13. Synthesis of (+/-)-clusianone: high-yielding bridgehead and diketone substitutions by regioselective lithiation of enol ether derivatives of bicyclo[3.3.1]nonane-2,4,9-triones.

    Science.gov (United States)

    Rodeschini, Vincent; Ahmad, Nadia M; Simpkins, Nigel S

    2006-11-09

    [Structure: see text] A concise synthesis of the polyprenylated acylphloroglucinol natural product, clusianone, in racemic form, is described. An Effenburger cyclization generated a core bicyclo[3.3.1]nonane-trione structure, which was then elaborated by means of regioselective lithiation reactions.

  14. RESGPSLNS_JD249.SHP: Ship Trackline along which Continuous Resistivity Profile Data was Collected in the Potomac River/Chesapeake Bay on Sept., 6, 2006 on USGS Cruise 06018

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — In order to test hypotheses about groundwater flow under and into Chesapeake Bay, geophysical surveys were conducted by U.S. Geological Survey (USGS) scientists on...

  15. Assessment of dietary exposure to annatto (E160b), nitrites (E249-250), sulphites (E220-228) and tartaric acid (E334) in the French population: the second French total diet study.

    Science.gov (United States)

    Bemrah, N; Vin, K; Sirot, V; Aguilar, F; Ladrat, A-C; Ducasse, C; Gey, J-L; Rétho, C; Nougadere, A; Leblanc, J-C

    2012-01-01

    The results of the assessment of the dietary exposure to annatto, nitrites, tartaric acid and sulphites within the framework of the second French total diet study (TDS) are reported. These 4 additives were selected from the Bemrah et al. study [Bemrah N, Leblanc JC, Volatier JL. 2008. Assessment of dietary exposure in the French population to 13 selected food colours, preservatives, antioxidants, stabilizers, emulsifiers and sweeteners. Food Addit Contam B. 1(1):2-14] on 13 food additives which identified a possible health risk for annatto, sulphites and nitrites and a lack of data for tartaric acid. Among the composite samples selected for the whole TDS, 524 were analysed for additives (a sample was analysed for a given additive when it was identified as a major contributor for this additive only): 130 for tartaric acid, 135 for nitrites, 59 for annatto and 200 for sulphites. Estimated concentrations (minimum lower bound to maximum upper bound) vary nationally from 0 to 9 mg/kg for annatto, 0 to 420 mg/kg for tartaric acid, 0 to 108 mg/kg for sulphites and 0 to 3.4 mg/kg for nitrites. Based on the analytical results, the dietary exposure was calculated for adults and children, separately, using lower bound and upper bound assumptions. The European ADIs for these 4 additives were not exceeded except for the dietary exposure for sulphites among 2.9% of the adult population, where the major contributors were alcoholic drinks and especially wine under both hypotheses (lower and upper bound).

  16. CTD data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 miles north of Oahu, Hawaii for cruises HOT249-258 during 2013 (NODC Accession 0125647)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. The program began in 1988....

  17. Prevalência da mutação ser-249 no gene TP53 em pacientes com carcinoma hepatocelular e cirrose hepática sem carcinoma hepatocelular diagnosticados em Vitória, Espírito Santo

    OpenAIRE

    Fernanda Magri de Carvalho

    2009-01-01

    A incidência do carcinoma hepatocelular (CHC) apresenta grandes variações geográficas associadas a diferentes prevalências dos seus fatores etiológicos mais comuns. Embora não se conheça a sua real incidência no Espírito Santo, o CHC é freqüentemente diagnosticado no estado, associado à infecção com os vírus da hepatite B (VHB) e da hepatite C. No entanto, cerca de 40% dos casos não apresentam evidências destes fatores etiológicos. Por essa razão, buscou-se verificar se outro fator aflatoxin...

  18. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

    DEFF Research Database (Denmark)

    Moesgaard Iburg, Kim

    2016-01-01

    also expanded the database of vital registration, survey, and census data to 14 294 geography–year datapoints. For GBD 2015, eight causes, including Ebola virus disease, were added to the previous GBD cause list for mortality. We used six modelling approaches to assess cause-specific mortality...

  19. Summary Health Statistics for U.S. Adults: National Health Interview Survey, 2009. Data from the National Health Interview Survey. Vital and Health Statistics. Series 10, Number 249. DHHS Publication No. (PHS) 2011-1577

    Science.gov (United States)

    Pleis, J. R.; Ward, B. W.; Lucas, J. W.

    2010-01-01

    Objectives: This report presents health statistics from the 2009 National Health Interview Survey (NHIS) for the civilian noninstitutionalized adult population, classified by sex, age, race and ethnicity, education, family income, poverty status, health insurance coverage, marital status, and place and region of residence. Estimates are presented…

  20. Navigation and Bathymetry Points of Ship Position During Continuous Resistivity Profile Data Collection in the Potomac River/Chesapeake Bay on Sept. 6, 2006 on USGS Cruise 06018 (RESGPSPNTS_JD249.SHP)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — In order to test hypotheses about groundwater flow under and into Chesapeake Bay, geophysical surveys were conducted by U.S. Geological Survey (USGS) scientists on...

  1. Avaliação nutricional da casca de soja integral ou moída, ensilada ou não, para suínos em fase de crescimento - DOI: 10.4025/actascianimsci.v29i1.249 Nutritional evaluation of whole or grinder soybean hull, ensilaged or not, for growing pigs - DOI: 10.4025/actascianimsci.v29i1.249

    Directory of Open Access Journals (Sweden)

    Cleber Rogério Ribeiro

    2007-11-01

    Full Text Available Foi conduzido um experimento com 11 suínos híbridos, machos castrados, com peso vivo de 41,42 ± 0,99 kg. Os animais foram alojados individualmente em gaiolas de metabolismo e distribuídos em um delineamento experimental inteiramente casualizado, com parcelas subdivididas, com quatro tratamentos em esquema fatorial 2 x 2 (moagem x ensilagem. Os alimentos avaliados foram: a casca de soja (CS integral (CSI, CS moída (CSM, silagem de CSI (SCSI e silagem de CSM (SCSM, que substituíram, com base na matéria seca (MS, 25% da ração referência e resultaram em quatro rações teste, sendo adicionado um inoculante enzimático microbiano nas silagens. Houve diferença somente para o CDPB em relação ao processamento da CS (ensilada = 68,08% e não ensilada = 59,44%. Conclui-se que a moagem e/ou ensilagem da CS, não tem efeito sobre a digestibilidade da MS, da MO, da EB, bem como sobre a metabolizabilidade da energia bruta. A ensilagem aumenta a digestibilidade da PB da casca de soja.An experiment was carried out using 11 crossbred pigs, barrows with body weight of 41.42 ± 0.99 kg. Pigs were allotted in metabolism cages, in a complete randomized design, in a split-plot design, with four treatments in a 2 x 2 (grinding x ensilage factorial and two replicates. Soybean hull (SH in the whole form (WSH, ground SH (GSH, WSH silage (WSHS and GSH silage (GSHS, that replaced (based on dry matter 25% of the reference diet, were evaluated resulting in four test diets. Enzymatic microbial inoculants were included in the silages production. Crude protein digestibility coefficient of soybean hull ensilage (68.08% was higher than no silage (59.44%, regardless grinding. Results showed that grinding and/or ensilage do not modify dry matter, organic matter, and gross energy digestibility, as well as energy metabolism. The ensilage process increases the crude protein digestibility coefficient of soybean hull, regardless grinding.

  2. Dollar Summary of Prime Contract Awards by Contractor, State or Country, and Place, FY83, Part 2 (Gillespie Delorenzo Asla & Assocs-Planning Analysis Corp).

    Science.gov (United States)

    1983-01-01

    ICELAND 30 30 30 30 GUENTER CLAJUS GERMANY 249 249 249 249 GUENTER SCHOLTYSEK GERMANY 184 184 184 184 GUERRA OLIVERIO FLORIDA CITY FLORIDA 25 25 25 25...39 39 39 39 MUNCK SYSTEMS INC HAMPTON VIRGINIA 113 113 113 113 MUNDIAL CONFIANCA AZORES 61 61 61 61 MUNDTH J J CONSTRUCTION CO ABERDEEN PROV GRND

  3. Gclust Server: 172773 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 172773 DME_CG12611_85726392 Cluster Sequences - 249 Andorra: Andorra CG12611-PA 1 1...ter sequences Cluster Sequences Link to related sequences - Sequence length 249 Representative annotation Andorra: Andorra

  4. Roman for unge - og deres voksne - fra Nick Hornby

    DEFF Research Database (Denmark)

    Haarder, Jon Helt

    2007-01-01

    Nick Hornby: SLAM. Oversat fra engelsk. af Jan Hansen. 280 sider, 249 kr. Lindhardt og Ringhof. Fire stjerner Udgivelsesdato: 071207......Nick Hornby: SLAM. Oversat fra engelsk. af Jan Hansen. 280 sider, 249 kr. Lindhardt og Ringhof. Fire stjerner Udgivelsesdato: 071207...

  5. Gclust Server: 76570 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 76570 HSA_8923040 Cluster Sequences Related Sequences(249) 580 NP_060102.1 collabor...elated sequences Related Sequences(249) Sequence length 580 Representative annotation NP_060102.1 collabor

  6. Gclust Server: 92033 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 92033 PoTR_571485 Cluster Sequences Related Sequences(249) 100 eugene3.00130849 1 1...ces Cluster Sequences Link to related sequences Related Sequences(249) Sequence length 100 Representative annotation eugene

  7. Gclust Server: 172174 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 172174 TET_249.m00042 Cluster Sequences - 21 hypothetical protein chr_0_8254705_249...; no annotation 1 1.00e-99 0.0 11.11 0.0 0.0 0.0 0.0 Show 172174 Cluster ID 172174 Sequence ID TET_249.m0004

  8. Struggling to Improve Our Understanding of Nursing Student Information Needs. A review of: Gannon‐Leary, Pat, Graham Walton, Raffik Cader, Julie Derbyshire, and Ann Smith. “Use of Evidence by Nursing Students: An Interdisciplinary Study.” Library & Information Science Research 28.2 (Mar. 2006: 249‐64.

    Directory of Open Access Journals (Sweden)

    Michael Corkett

    2007-06-01

    Full Text Available Objective – To identify the sources used by student nurses when undertaking a health needs analysis of particular client groups, and to determine students’ ease in accessing source materials.Design – Case series, incorporating citation analysis and focus groups.Setting – Honours Nursing Studies program (Adult Branch, Northumbria University, Newcastle upon Tyne, United Kingdom.Subjects – Citation analysis: 40 students undertaking health needs analysis assignment. Focus groups: 2 groups of 8 students.Methods – Subjects for the citation analysis were not randomly selected. Citation analysis was performed and references tabulated using a previously piloted proforma. Distribution of references between sources was measured using quantitative analysis. Focus groups consisted of self selecting volunteers from the student cohort undertaking the assignment. Issues of potential bias/coercion relating to research team members being group participant tutors were addressed. Results were analysed through the categorisation of key themes.Main results – The mean number of sources cited per assignment was 16. More than half( 56% of the sources were published after 1999. Twenty‐nine percent of citations were published between 1996 and 1999, and 12% between 1990 and 1995. Only small percentages were published in the 1980s (2% and 1970s (1%. Journals (37% formed the largest body of references, followed by books at 27%. UK government publications accounted for 14% of total references; Web based resources totalled 12%. Students acknowledged the importance of supporting assignments with references. Government publications were recognised as high quality pieces of evidence. Difficulty was experienced extrapolating evidence from different care settings and moving outside of usual parameters. Students indicated that statistical data was hard to find. Those without home Internet facilities had greater difficulty in accessing information than students with such facilities. Support from information professionals was received, but quality was variable.Conclusion – Doubts exist as to whether opportunities for student learning to inform educators are being fully exploited. Upon completion of assignments students are arguably in a better position to debate subjects more deeply and so advance understanding. Potential for peer group development may be lost. Collaboration between nursing academics and information professionals offers potential for nursing students and health professionals to advance their exploitation and evaluation of information resources.

  9. Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France.

    Science.gov (United States)

    Mancini, F R; Paul, D; Gauvreau, J; Volatier, J L; Vin, K; Hulin, M

    2015-01-01

    This study aimed to estimate the exposure to seven additives (benzoates, parabens, nitrites, nitrates, BHA, BHT and aspartame) in children aged less than 3 years old in France. A conservative approach, combining individual consumption data with maximum permitted levels, was carried out for all the additives. More refined estimates using occurrence data obtained from products' labels (collected by the French Observatory of Food Quality) were conducted for those additives that exceeded the acceptable daily intake (ADI). Information on additives' occurrence was obtained from the food labels. When the ADI was still exceeded, the exposure estimate was further refined using measured concentration data, if available. When using the maximum permitted level (MPL), the ADI was exceeded for benzoates (1.94 mg kg(-1) bw day(-1)), nitrites (0.09 mg kg(-1) bw day(-1)) and BHA (0.39 mg kg(-1) bw day(-1)) in 25%, 54% and 20% of the entire study population respectively. The main food contributors identified with this approach were current foods as these additives are not authorised in specific infant food: vegetable soups and broths for both benzoates and BHA, delicatessen and meat for nitrites. The exposure estimate was significantly reduced when using occurrence data, but in the upper-bound scenario the ADI was still exceeded significantly by the age group 13-36 months for benzoates (2%) and BHA (1%), and by the age group 7-12 months (16%) and 13-36 months (58%) for nitrites. Measured concentration data were available exclusively for nitrites and the results obtained using these data showed that the nitrites' intake was below the ADI for all the population considered in this study. These results suggest that refinement of exposure, based on the assessment of food levels, is needed to estimate the exposure of children to BHA and benzoates for which the risk of exceeding the ADI cannot be excluded when using occurrence data.

  10. TOWARD AN IMPROVED UNDERSTANDING OF STRUCTURE AND MAGNETISM IN NEPTUNIUM AND PLUTONIUM PHOSPHONATES AND SULFONATES

    Energy Technology Data Exchange (ETDEWEB)

    Albrecht-Schmitt, Thomas

    2012-03-01

    This grant supported the exploratory synthesis of new actinide materials with all of the actinides from thorium to californium with the exceptions of protactinium and berkelium. We developed detailed structure-property relationships that allowed for the identification of novel materials with selective ion-exchange, selective oxidation, and long-range magnetic ordering. We found novel bonding motifs and identified periodic trends across the actinide series. We identified structural building units that would lead to desired structural features and novel topologies. We also characterized many different spectroscopic trends across the actinide series. The grant support the preparation of approximately 1200 new compounds all of which were structurally characterized.

  11. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  12. PROCEEDINGS OF THE SYMPOSIUM COMMEMORATING THE 25th ANNIVERSARY OF ELEMENTS 97 and 98 HELD ON JAN. 20, 1975

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, Glenn T.; Street Jr., Kenneth; Thompson, Stanley G.; Ghiorso, Albert

    1976-07-01

    This volume includes the talks given on January 20, 1975, at a symposium in Berkeley on the occasion of the celebration of the 25th anniversary of the discovery of berkelium and californium. Talks were given at this symposium by the four people involved in the discovery of these elements and by a number of people who have made significant contributions in the intervening years to the investigation of their nuclear and chemical properties. The papers are being published here, without editing, in the form in which they were submitted by the authors in the months following the anniversary symposium, and they reflect rather faithfully the remarks made on that occasion.

  13. Dicty_cDB: [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFC249 (Link to dictyBase) - - - Contig-U16272-1 VFC249P (Link... to Original site) VFC249F 500 VFC249Z 585 VFC249P 1085 - - Show VFC249 Library VF (Link to library) Clone ID VFC249 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16272-1 Original site URL http://dict...te 2004.12.25 Homology vs DNA Score E Sequences producing significant alignments: (bits) Value N L08391 |L08391.1 Dict...0.00 mNt: 0.00 m3a: 0.00 m3b: 0.00 m_ : 1.00 88.0 %: cytoplasmic 8.0 %: mitochondrial 4.0 %: nuclear >> predict

  14. Superheavy Element Research at Tasca at GSI

    Science.gov (United States)

    Düllmann, Christoph E.

    2014-09-01

    Experiments on the synthesis of the heaviest elements are in the center of the current research program on superheavy elements at GSI Darmstadt. At the gas-filled recoil separator TASCA, search experiments for the new elements 119 and 120 have been performed in the reactions 50Ti + 249Bk and 50Ti + 249Cf, respectively, and the production of element 117 in the reaction 48Ca + 249Bk was studied. The experiments were performed successfully and the data are currently under analysis.

  15. Dicty_cDB: Contig-U10137-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LTNHFNKVNELLNDWDGVGLSHELSMTELITSILNSINHNSHSGMSNQKKQQIQAKV 60 Query: 249 NQIKKTDLVVKRQQDIDTLCAN...KIQHNYNEIVAYRLRSISSLLDSKYYDAFRYLIEAINS 428 NQIKKTDLVVKRQQDIDTLCANKIQHNYNEIVAYRLRSISSLLDSKYYDAFR...YLIEAINS Sbjct: 61 NQIKKTDLVVKRQQDIDTLCANKIQHNYNEIVAYRLRSISSLLDSKYYDAFRYLIEAINS 120 Query: 429 FVKVFELWSQNIL

  16. Significance of mangrove swamps for aquaculture

    Digital Repository Service at National Institute of Oceanography (India)

    Wafar, S.; Untawale, A.G.

    stream_size 9 stream_content_type text/plain stream_name I.O_21_Century_Linkage_Networking_1998_249.pdf.txt stream_source_info I.O_21_Century_Linkage_Networking_1998_249.pdf.txt Content-Encoding ISO-8859-1 Content-Type text...

  17. Proceedings of the 1993 Particle Accelerator Conference Held in Washington, DC on May 17-20, 1993. Volume 3

    Science.gov (United States)

    1993-05-20

    8My9 Christoph Leemann, CEBAF18My9 Annie Soltys. Executive Assistant Telephone: (804) 249-7575 E-mail: soltyu~cebaf.gov Fax: (804) 249.5024 DEFENSE...m] 10.1,7.9 8.6,8.6 now, M. Stampfer , E. Jaeschke and M. Steck, Advanced Stacking Methods Using Electron Cooling at the TSR, 1991 IEEE Particle

  18. 17 CFR 240.15Bc3-1 - Withdrawal from registration of municipal securities dealers.

    Science.gov (United States)

    2010-04-01

    ... bank or a separately identifiable department or division of a bank, or Form BDW (17 CFR 249.501a), in... securities dealer that is filed on Form BDW (17 CFR 249.501a) shall be filed with the Central Registration Depository (operated by the Financial Industry Regulatory Authority, Inc.) in accordance with...

  19. Drug: D08153 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08153 Drug Mabuprofen (INN); Aldospray analgesico (TN) C15H23NO2 249.1729 249.3486 D08153.gif Antiinflammat...ory; Analgesic CAS: 82821-47-4 PubChem: 96024843 LigandBox: D08153 NIKKAJI: J321.96

  20. Review of: Islam, Migration and Integration: The Age of Securitization

    DEFF Research Database (Denmark)

    Vinding, Niels Valdemar

    2010-01-01

    Islam, Migration and Integration: The Age of Securitization. By Ayhan Kaya. (Migration, Minorities and Citizenship). Houndmills, Basingstoke: Palgrave Macmillan, 2009. Pp. xiv+249. Hbk 978-0-230-51679-3. £55.......Islam, Migration and Integration: The Age of Securitization. By Ayhan Kaya. (Migration, Minorities and Citizenship). Houndmills, Basingstoke: Palgrave Macmillan, 2009. Pp. xiv+249. Hbk 978-0-230-51679-3. £55....

  1. 17 CFR 229.1101 - (Item 1101) Definitions.

    Science.gov (United States)

    2010-04-01

    ... type of assets comprising the pool and the programs under which the loans were originated; (3... additional assets to the pool that backs such securities in connection with future issuances of asset-backed... either Item 6.05 of Form 8-K (17 CFR 249.308) or in a Form 10-D (17 CFR 249.312) pursuant to Item...

  2. Drug: D03107 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available t of prostate cancers [inhibits human type I isoform of 5alpha-reductase] 5alpha-reductase 1 inhibitor [HSA:...D03107 Drug Bexlosteride (USAN/INN) C14H16ClNO 249.092 249.7359 D03107.gif Treatmen

  3. 78 FR 40402 - Radio Broadcasting Services; Roaring Springs, Texas

    Science.gov (United States)

    2013-07-05

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Roaring Springs, Texas AGENCY: Federal Communications... Channel 227A and deletes FM Channel 249A at Roaring Springs, Texas, and allots FM Channel 249C3 and deletes FM Channel 276C3 at Roaring Springs. These allotment changes are part of a rule making and...

  4. Preformulation and Formulation of Investigational New Drugs

    Science.gov (United States)

    1985-07-01

    WR249,655𔃼CL and WR249,943𔃼C1..; physicochemical characterization of WR238,6O𔃿 investigation of solid-state properties of various lots of WRl71,669...Methocel XD-30018.OO--Hydroxypropylmethylceilulose, US? 2208(100,000 cps) Sodium CMC 7HP --------Sodium carboxymethylcellulose (DS-0.7, high viscosity

  5. Nuclear fission and the transuranium elements

    Energy Technology Data Exchange (ETDEWEB)

    Seaborg, G.T.

    1989-02-01

    Many of the transuranium elements are produced and isolated in large quantities through the use of neutrons furnished by nuclear fission reactions: plutonium (atomic number 94) in ton quantities; neptunium (93), americium (95), and curium (96) in kilogram quantities; berkelium (97) in 100 milligram quantities; californium (98) in gram quantities; and einsteinium (99) in milligram quantities. Transuranium isotopes have found many practical applications---as nuclear fuel for the large-scale generation of electricity, as compact, long-lived power sources for use in space exploration, as means for diagnosis and treatment in the medical area, and as tools in numerous industrial processes. Of particular interest is the unusual chemistry and impact of these heaviest elements on the periodic table. This account will feature these aspects. 9 refs., 5 figs.

  6. Novel Molecular Imaging Agents to Detect Biomarkers of Metastatic Breast Cancer

    Science.gov (United States)

    2006-01-01

    19) Tsujimoto, T.; Murai A.; Synlett , 2002, 8, 1283-1284. (20) Gisin, B. Anal. Chim. Acta, 1972, 58, 248-249. (21) Fields, C. G.; Lloyd, D. H...New York, 1992, 77-183. (4) Tsujimoto, T.; Murai A.; Synlett , 2002, 8, 1283-1284. (5) Gisin, B. Anal. Chim. Acta, 1972, 58, 248-249 (6) Fields, C...T.; Murai A.; Synlett , 2002, 8, 1283-1284. (5) Gisin, B. Anal. Chim. Acta, 1972, 58, 248-249. (6) Fields, C. G.; Lloyd, D. H.; Macdonald, R. L.; Otteson, K. M.; Noble, R. L. Peptide Res., 1991, 4, 95-101.

  7. 76 FR 1492 - Notice of Actions Taken at December 16, 2010, Meeting

    Science.gov (United States)

    2011-01-10

    ...: Hughesville-Wolf Township Joint Municipal Authority. Project Facility: Wastewater Treatment Plant, Wolf Township, Lycoming County, Pa. Withdrawal of treated wastewater effluent of up to 0.249 mgd. 6....

  8. Gclust Server: 91946 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available sequences Cluster Sequences Link to related sequences Related Sequences(249) Sequence length 231 Representative...ld 1.00e-80 Plants and algae (7species) (%) 14.29 Other Bikonts (Chromalveolata, Excavata) (9species) (%) 0.

  9. Gclust Server: 183506 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available nces Cluster Sequences Link to related sequences - Sequence length 249 Representative annotation no annotati...e (7species) (%) 0.0 Other Bikonts (Chromalveolata, Excavata) (9species) (%) 11.11 Cyanobacteria (25species)

  10. Disease: H00905 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Bockenhauer D, Kleta R Aminoacidurias: Clinical and molecular aspects. Kidney In...mmalian intestinal and renal epithelia. Physiol Rev 88:249-86 (2008) PMID:18200002 (description) Camargo SM,

  11. EST Table: BB985913 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to putative lysosomal glucocerebrosidase [Tribolium castaneum] 10/08/28 30 %/249 aa FBpp0129766|DereGG112...EDICTED: similar to putative lysosomal glucocerebrosidase [Tribolium castaneum] BB985877 MSV3 ...

  12. Temperature, salinity, oxygen, nutrients and productivity profile data from THOMAS G. THOMPSON Cruise 001, 19651014 to 19651207 in the Caribbean Sea and the northeastern tropical Pacific Ocean (NODC Accession 7100507)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains a copy of University of Washington Department of Oceanography Technical Report No. 249, Physical, chemical, and productivity data from a...

  13. 1983 walrus harvest, health, and welfare study at Gambell, Alaska: Progress report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The total documented harvest during the period of observation in 1983 was 642 walruses. This included 249 adult males (38.8%), 203 adult females (31.6%), and 190...

  14. Drug: D10250 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 249]) treatment of opioid dependence ATC code: N07BC51 Anatomical Therapeutic Chemical (ATC) classification ...DDICTIVE DISORDERS N07BC Drugs used in opioid dependence N07BC51 Buprenorphine, combinations D10250 Buprenor

  15. Italian Foreign Policy: Trends for the Twenty-First Century

    Science.gov (United States)

    2003-06-01

    85 Ibid. 86 Carlo Jean, Geopolitica , (Bologna, Laterza, 1996), 249. 87 Ibid. 42 88 Ibid. control of jurisdiction over...L. Nacos, et al, eds., (Lanham, MD, Rowman and Littlefield, 2000). Jean, Carlo. Geopolitica ,(Bologna, Laterza, 1996). Jean, Carlo. Guerra

  16. 75 FR 33901 - Physical Protection of Byproduct Material

    Science.gov (United States)

    2010-06-15

    ..., 2006), and licensees making shipments of category 1 quantities of radioactive material (EA-06-249) (71...; manufacturer and distributor licensees; medical facilities with gamma knife devices; self-shielded...

  17. Gene : CBRC-MDOM-11-0012 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available ica protamine 1 (PRM1), mRNA /cds=p(73,249) /gb=NM_001032967 /gi=74136486 /ug=Mdm.246 /len=400 0.004 29% MEGKGKKKRKKERKKERKKERKKERK...KERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERERERKKERKKVRKRERKKERKREREKERKKERKKERK...RERKREREKERKREREKERKKEREKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKEKKEKRRREMKSQRGEVLKVVQRRRARI ...

  18. Gene : CBRC-MDOM-08-0074 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available ca protamine 1 (PRM1), mRNA /cds=p(73,249) /gb=NM_001032967 /gi=74136486 /ug=Mdm.246 /len=400 2e-04 25% MIFRINSKIESKNFLRKERKKERK...KERRKKERRKKKKERKKERRKKKERRRRKKEEREREREREREPVEKEREKKERKRESLRERKNERKKERKKERKKDRQKERKKERK...KERKKERKKERKKERKKERKKERKKEREKEREREREKERKREREKERKKERKKERKKERKKERKKERKKERKKESERKGEKGRETHEEREKQRKKKKKGSKKKK ...

  19. Gene : CBRC-MDOM-04-0419 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available ca protamine 1 (PRM1), mRNA /cds=p(73,249) /gb=NM_001032967 /gi=74136486 /ug=Mdm.246 /len=400 0.002 24% MRFEPRSSGSRASALSTINVLRKKERK...KERKKERKKERKKERKKERKKERKKERKKERKKERKKERKEERKKERKKERKKERKKERKEERKKGRKKERKKERK...KGRKEGRKEERKEERKKGRKEERKKGRKEERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERVRSGRDLRT ...

  20. Gene : CBRC-MDOM-01-0367 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available ca protamine 1 (PRM1), mRNA /cds=p(73,249) /gb=NM_001032967 /gi=74136486 /ug=Mdm.246 /len=400 0.002 40% MEGKGEERKRERKKERKREREKERKKERK...KERKKERKKERKKERKKERKKERKKERKKERKREREKERKREREKERKKERKKERKKERERKKERKRERQERKKERKKERK...KERKKERKKERKKERKKERKKERKKERKKGRKEGRKEGRKEGRKEERKKERKKERKKERKKERKKERKKERKKERKEGRKEGR

  1. Gene : CBRC-MDOM-03-0097 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available mestica protamine 1 (PRM1), mRNA /cds=p(73,249) /gb=NM_001032967 /gi=74136486 /ug=Mdm.246 /len=400 3e-04 31% MCRKKEKKKERKKERKKERKKERK...KERERKRERERKKERERERERKKERKKERKKERKKERKKERKKERERERERRRERKREREKEKERKREREKERK...REREKERKREREKERKREREKERKREREKERKKERKKERKKERKKERKKERKKERKKERKKERKGGRKEGRKEGRKEGRKEGRKEGERKGGRRRNRKGRGVEEGRER ...

  2. QTL Information Table: 836 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available Physiological trait Source activity Starch/sucrose RFLP d)Co-segregated BC1F7 Nippo...nbare Kasalath C249 pha Ishimaru, K., Hirotsu, N., Madoka, Y., and Kashiwagi, T. (2007). Quantitative trait

  3. Poliomyelitis

    Science.gov (United States)

    ... that may result from polio include: Aspiration pneumonia Cor pulmonale (a form of heart failure found on the ... Saunders; 2015:chap 249. Read More Aspiration pneumonia Cor pulmonale Incidence Intestinal obstruction Kidney stones Lymph system Muscle ...

  4. Domain Modeling: NP_000482.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_000482.3 chr1 TNF-like d1o91a_ chr1/NP_000482.3/NP_000482.3_apo_120-249.pdb d1o91c_ chr1/NP_000482.3.../NP_000482.3_holo_120-249.pdb blast 179N,181C,197F,228D,230N,231S 120Q,121K,122I,123A,12

  5. Recension: Efectos personales del divorcio respecto de los hijos – Review: Personal Effects of Divorce in Relation to Children

    Directory of Open Access Journals (Sweden)

    Teresa Dupla Marin

    2013-05-01

    Full Text Available Recension: Carmen López‐Rendo Rodríguez, Efectos personales del divorcio respecto de los hijos, De Roma al Codigo civil español, RIDROM (online 9, 2012, Pág. 249–270Review: Carmen López‐Rendo Rodríguez, Personal Effects of Divorce in Relation to Children, from Classical Rome to the Spanish Civil Code, RIDROM (online 9, 2012, pp. 249–270

  6. GETDB: 113515 [GETDB

    Lifescience Database Archive (English)

    Full Text Available Ser Link to clone table - 1 2063 Link to cluster table 2063 1 Request - pns (ch subset) gut sg, fb, mt - lethal - comment1:A, D, com...wn as - Original Comments comment1:A, D, comment2:49D2-D3, P and lethal on 2nd ch, lethal on 3rd ch Disc (Im...ment2:49D2-D3, P and lethal on 2nd ch, lethal on 3rd ch

  7. An exact exponential time algorithm for counting bipartite cliques

    DEFF Research Database (Denmark)

    Kutzkov, Konstantin

    2012-01-01

    We present a simple exact algorithm for counting bicliques of given size in a bipartite graph on n vertices. We achieve running time of O(1.249^n), improving upon known exact algorithms for finding and counting bipartite cliques.......We present a simple exact algorithm for counting bicliques of given size in a bipartite graph on n vertices. We achieve running time of O(1.249^n), improving upon known exact algorithms for finding and counting bipartite cliques....

  8. Polymorphism of the Fractalkine Receptor CX3CR1 and Systemic Sclerosis-associated Pulmonary Arterial Hypertension

    Directory of Open Access Journals (Sweden)

    Bianca Marasini

    2005-01-01

    Full Text Available Fractalkine (FKN and its receptor CX3CR1 are critical mediators in the vascular and tissue damage of several chronic diseases, including systemic sclerosis (SSc and pulmonary arterial hypertension (PAH. Interestingly, the V249I and T280M genetic polymorphisms influence CX3CR1 expression and function. We investigated whether these polymorphisms are associated with PAH secondary to SSc. CX3CR1 genotypes were analyzed by PCR and sequencing in 76 patients with limited SSc and 204 healthy controls. PAH was defined by colorDoppler echocardiography. Homozygosity for 249II as well as the combined presence of 249II and 280MM were significantly more frequent in patients with SSc compared to controls (17 vs 6%, p = 0.0034 and 5 vs 1%, p = 0.0027, respectively. The 249I and 280M alleles were associated with PAH (odd ratio [OR] 2.2, 95% confidence interval [CI] 1.01-4.75, p = 0.028 and OR 7.37, 95%CI: 2.45-24.60, p = 0.0001, respectively. In conclusion, the increased frequencies of 249I and 280M CX3CR1 alleles in a subgroup of patients with SSc-associated PAH suggest a role for the fractalkine system in the pathogenesis of this condition. Further, the 249I allele might be associated with susceptibility to SSc.

  9. Production and decay of the heaviest nuclei (293,294)117 and (294)118.

    Science.gov (United States)

    Oganessian, Yu Ts; Abdullin, F Sh; Alexander, C; Binder, J; Boll, R A; Dmitriev, S N; Ezold, J; Felker, K; Gostic, J M; Grzywacz, R K; Hamilton, J H; Henderson, R A; Itkis, M G; Miernik, K; Miller, D; Moody, K J; Polyakov, A N; Ramayya, A V; Roberto, J B; Ryabinin, M A; Rykaczewski, K P; Sagaidak, R N; Shaughnessy, D A; Shirokovsky, I V; Shumeiko, M V; Stoyer, M A; Stoyer, N J; Subbotin, V G; Sukhov, A M; Tsyganov, Yu S; Utyonkov, V K; Voinov, A A; Vostokin, G K

    2012-10-19

    Two years after the discovery of element 117, we undertook a second campaign using the (249)Bk+(48)Ca reaction for further investigations of the production and decay properties of the isotopes of element 117 on a larger number of events. The experiments were started in the end of April 2012 and are still under way. This Letter presents the results obtained in 1200 hours of an experimental run with the beam dose of (48)Ca of about 1.5×10(19) particles. The (249)Bk target was irradiated at two energies of (48)Ca that correspond to the maximum probability of the reaction channels with evaporation of three and four neutrons from the excited (297)117. In this experiment, two decay chains of (294)117 (3n) and five decay chains of (293)117 (4n) were detected. In the course of the long-term work, (249)Cf-the product of decay of (249)Bk (330 d)-is being accumulated in the target. Consequently, in the present experiment, we also detected a single decay of the known isotope (294)118 that was produced during 2002-2005 in the reaction (249)Cf((48)Ca,3n)(294)118. The obtained results are compared with the data from previous experiments. The experiments are carried out in the Flerov Laboratory of Nuclear Reactions, Joint Institute for Nuclear Research, using the heavy-ion cyclotron U400.

  10. Characterization of a Viking Blade Fabricated by Traditional Forging Techniques

    Science.gov (United States)

    Vo, H.; Frazer, D.; Bailey, N.; Traylor, R.; Austin, J.; Pringle, J.; Bickel, J.; Connick, R.; Connick, W.; Hosemann, P.

    2016-09-01

    A team of students from the University of California, Berkeley, participated in a blade-smithing competition hosted by the Minerals, Metals, and Materials Society at the TMS 2015 144th annual meeting and exhibition. Motivated by ancient forging methods, the UC Berkeley team chose to fabricate our blade from historical smithing techniques utilizing naturally-occurring deposits of iron ore. This approach resulted in receiving the "Best Example of a Traditional Blade Process/Ore Smelting Technique" award for our blade named "Berkelium." First, iron-enriched sand was collected from local beaches. Magnetite (Fe3O4) was then extracted from the sand and smelted into individual high- and low-carbon steel ingots. Layers of high- and low-carbon steels were forge-welded together, predominantly by hand, to form a composite material. Optical microscopy, energy dispersive spectroscopy, and Vickers hardness mechanical testing were conducted at different stages throughout the blade-making process to evaluate the microstructure and hardness evolution during formation. It was found that the pre-heat-treated blade microstructure was composed of ferrite and pearlite, and contained many nonmetallic inclusions. A final heat treatment was performed, which caused the average hardness of the blade edge to increase by more than a factor of two, indicating a martensitic transformation.

  11. Characterization of a Viking Blade Fabricated by Traditional Forging Techniques

    Science.gov (United States)

    Vo, H.; Frazer, D.; Bailey, N.; Traylor, R.; Austin, J.; Pringle, J.; Bickel, J.; Connick, R.; Connick, W.; Hosemann, P.

    2016-12-01

    A team of students from the University of California, Berkeley, participated in a blade-smithing competition hosted by the Minerals, Metals, and Materials Society at the TMS 2015 144th annual meeting and exhibition. Motivated by ancient forging methods, the UC Berkeley team chose to fabricate our blade from historical smithing techniques utilizing naturally-occurring deposits of iron ore. This approach resulted in receiving the "Best Example of a Traditional Blade Process/Ore Smelting Technique" award for our blade named "Berkelium." First, iron-enriched sand was collected from local beaches. Magnetite (Fe3O4) was then extracted from the sand and smelted into individual high- and low-carbon steel ingots. Layers of high- and low-carbon steels were forge-welded together, predominantly by hand, to form a composite material. Optical microscopy, energy dispersive spectroscopy, and Vickers hardness mechanical testing were conducted at different stages throughout the blade-making process to evaluate the microstructure and hardness evolution during formation. It was found that the pre-heat-treated blade microstructure was composed of ferrite and pearlite, and contained many nonmetallic inclusions. A final heat treatment was performed, which caused the average hardness of the blade edge to increase by more than a factor of two, indicating a martensitic transformation.

  12. Differential expression of carotenoid biosynthetic pathway genes in two contrasting tomato genotypes for lycopene content

    Indian Academy of Sciences (India)

    Shilpa Pandurangaiah; Kundapura V Ravishankar; Kodthalu S Shivashankar; Avverahally T Sadashiva; Kavitha Pillakenchappa; Sunil Kumar Narayanan

    2016-06-01

    Tomato (Solanum lycopersicum L.) is one of the model plants to study the carotenoid biosynthesis. In the present study, the fruit carotenoid content were quantified at different developmental stages for two contrasting genotypes viz. IIHR-249-1and IIHR-2866 by UPLC. Lycopene content was high in IIHR-249-1(19.45 mg/100g fresh weight) compared to IIHR-2866 ((1.88 mg/100g fresh weight) at the ripe stage. qPCR was performed for genes that are involved in the carotenoid biosynthetic pathway to study the difference in lycopene content in fruits of both the genotypes. The expression of Phytoene Synthase (PSY) increased by 36 fold and Phytoene desaturase (PDS) increased by 14fold from immature green stage to ripe stage in IIHR-249-1. The expression of Chloroplast lycopene β cyclase (LCY-B) and Chromoplast lycopene β cyclase (CYC-B) decreased gradually from the initial stage to the ripe stage in IIHR-249-1. IIHR 249-1 showed 3 and 1.8 fold decrease in gene expression for Chloroplast lycopene β cyclase ((LCY-B) and Chromoplast lycopene β cyclase (CYC-B) .The F2 hybrids derived from IIHR-249-1 and IIHR-2866 were analyzed at the ripe stage for lycopene content. The gene expression of Chloroplast lycopene β cyclase (LCY-B) and Chromoplast lycopene β cyclase (CYC-B) in high and low lycopene lines from F2 progenies also showed the decrease in transcript levels of both the genes in high lycopene F2 lines. We wish to suggest that the differential expression of Lycopene β -cyclases can be used in marker assisted breeding.

  13. Development of a Novel Therapeutic Paradigm Utilizing a Mammary Gland-Targeted, Bin 1-Knockout Mouse Model

    Science.gov (United States)

    2006-03-01

    observation that, in a diabetic mouse model, the ability of CTLA-4-Ig to effectively suppress immune rejection of pan- creatic islet allografts was lost if...T et al.: In vitro and in vivo formation of two new metabolites of melatonin . J. Biol. Chem. (1974) 249(4):1311-1313. 117. SONO M, TANIGUCHI T...Tokuyama, T., Seno, S. In vitro and in vivo formation of two new metabolites of melatonin . J Biol Chem 1974, 249(4): 1311-3. 26. Shimizu, T., Nomiyama, S

  14. CX3CR1 is a modifying gene of survival and progression in amyotrophic lateral sclerosis.

    Directory of Open Access Journals (Sweden)

    Alan Lopez-Lopez

    Full Text Available The objective of this study was to investigate the association of functional variants of the human CX3CR1 gene (Fractalkine receptor with the risk of Amyotrophic Lateral Sclerosis (ALS, the survival and the progression rate of the disease symptoms in a Spanish ALS cohort. 187 ALS patients (142 sporadic [sALS] and 45 familial and 378 controls were recruited. We investigated CX3CR1 V249I (rs3732379 and T280M (rs3732378 genotypes and their haplotypes as predictors of survival, the progression rate of the symptoms (as measured by ALSFRS-R and FVC decline and the risk of suffering ALS disease. The results indicated that sALS patients with CX3CR1 249I/I or 249V/I genotypes presented a shorter survival time (42.27 ± 4.90 than patients with 249V/V genotype (67.65 ± 7.42; diff -25.49 months 95%CI [-42.79,-8.18]; p = 0.004; adj-p = 0.018. The survival time was shorter in sALS patients with spinal topography and CX3CR1 249I alleles (diff =  -29.78 months; 95%CI [-49.42,-10.14]; p = 0.003. The same effects were also observed in the spinal sALS patients with 249I-280M haplotype (diff =  -27.02 months; 95%CI [-49.57, -4.48]; p = 0.019. In the sALS group, the CX3CR1 249I variant was associated with a faster progression of the disease symptoms (OR = 2.58; 95IC% [1.32, 5.07]; p = 0.006; adj-p = 0.027. There was no evidence for association of these two CX3CR1 variants with ALS disease risk. The association evidenced herein is clinically relevant and indicates that CX3CR1 could be a disease-modifying gene in sALS. The progression rate of the disease's symptoms and the survival time is affected in patients with one or two copies of the CX3CR1 249I allele. The CX3CR1 is the most potent ALS survival genetic factor reported to date. These results reinforce the role of the immune system in ALS pathogenesis.

  15. Discovery of the New Element Z=117 and Confirmation of 115

    OpenAIRE

    Oganessian Yu.Ts.; Hamilton J.H.; Utyonkov V. K.

    2011-01-01

    The discovery of the new chemical element with atomic number Z=117 is presented. The isotopes 293 117 and 294117 were produced in fusion reactions between 48Ca and 249Bk. The 249Bk was produced in the High Flux Isotope Reactor and chemically separated at Oak Ridge. Decay chains involving eleven new nuclei were identified by means of the Dubna Gas-Filled Recoil Separator. The measured decay properties show a strong rise of stability for superheavy nuclei toward N=184.The reaction 243Am+48Ca wa...

  16. Study on hydrogen assisted cracking susceptibility of HSLA steel by implant test

    OpenAIRE

    2016-01-01

    DMR-249A is an indigenously developed high strength low alloy steel for Indian ship building industry for making ship-hull and is extensively used in the construction of war ships and submarines. Welding electrodes conforming to SFA 5.5 AWS E8018 C1 has been indigenously developed for welding of this steel using shielded metal arc welding process. In the present study, susceptibility to hydrogen assisted cracking of DMR-249A steel welds made using this electrode has been assessed using implan...

  17. HEMATOPOIETIC SYSTEM

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    12.1 Leukocyte and leukocyte function2003360 Expression of vascular endothelial growth factor and its receptors KDR and Fltl in acute myeloid leukemia. WANG Yi(王一), et al. Instit Hematol, CAMS & PUMC, Tianjin 300020. Chin J Hematol 2003;24(5):249-252Objective: To evaluate the expression of vascular endothelial growth factor (VEGF) and its receptors KDR

  18. Causal Model of Stress and Coping: Women in Management.

    Science.gov (United States)

    Long, Bonita C.; And Others

    1992-01-01

    Tested model of managerial women's (n=249) stress. Model was developed from Lazarus's theoretical framework of stress/coping and incorporated causal antecedent constructs (demographics, sex role attitudes, agentic traits), mediating constructs (environment, appraisals, engagement coping, disengagement coping), and outcomes (work performance,…

  19. (5-Benzoyl-2-methyl-4-{[1-(pyridin-4-yl-1H-1,2,3-triazol-4-yl]methoxy}-1-benzofuran-7-yl(phenylmethanone

    Directory of Open Access Journals (Sweden)

    Xiao-qin Zhang

    2012-06-01

    Full Text Available The crystal structure of the title compound, C31H22N4O4, features weak C—H...O interactions. The dihedral angle between the fused benzene and furan rings is 2.49 (15°, while that between the triazole and pyridine rings is 10.23(18°.

  20. A Cross-Sectional Study of Clinical Features and Management of Liver Abscesses in a Tertiary Care Hospital, Ahmedabad, Gujarat

    Directory of Open Access Journals (Sweden)

    Tejas N Hathila

    2014-09-01

    Conclusion: We conclude from the study that needle aspiration combined with antibiotics represent a successful therapeutic approach in the treatment of liver abscess. Open surgical drainage is usually reserved for complications like rupture in peritoneum. [Natl J Med Res 2014; 4(3.000: 249-252

  1. Sobre la historia de la traducción en España

    Directory of Open Access Journals (Sweden)

    Manuel Bruña Cuevas

    2011-01-01

    Full Text Available A propósito de la obra de Francisco Lafarga y Luis Pegenaute (eds., Diccionario histórico de la traducción en España (Madrid, Gredos, 2009; 1232 páginas. ISBN: 978-84-249-3626-6.

  2. Balti kirjakultuuri mitmekeelsest loomust / Liina Lukas

    Index Scriptorium Estoniae

    Lukas, Liina, 1970-

    2008-01-01

    Poleemika senise rahvuslik-keelelise lähenemisega eesti varasemale kirjandusloole. 17. saj. Eestimaal viljeldud uusladina luulest Euroopa kirjandusnähtuste taustal (ka Reiner Brockmanni eestikeelsest juhuluuleharrastusest) ning 19. saj. lõpuni püsinud mitmekeelsusest siinses kultuuris. Ka ettepanek kasutada seoses Eestimaa mitmekeelse kultuuriga "balti kirjakultuuri" mõistet. Sisaldab bibliograafiat. Autorist lk. 249

  3. Taking Care of Yourself

    Science.gov (United States)

    ... is 18.5–24.9 kg/m 2 Waist circumference not more than 40 inches for men and ... help you determine if you're overweight. Your waist circumference also helps determine whether you need to lose ...

  4. Information Activities and Appropriation in Teacher Trainees' Digital, Group-Based Learning

    Science.gov (United States)

    Hanell, Fredrik

    2016-01-01

    Introduction: This paper reports results from an ethnographic study of teacher trainees' information activities in digital, group-based learning and their relation to the interplay between use and appropriation of digital tools and the learning environment. Method: The participants in the present study are 249 pre-school teacher trainees in…

  5. 32 CFR 239.9 - Application Processing Procedures.

    Science.gov (United States)

    2010-07-01

    ... = Military PCS. (iv) State: State abbreviation. (v) Installation Number: The five digit ZIP code of the... which they depart. (vi) Application Number: Sequential beginning with 0001. ER30SE09.249 (d) Real Estate Values. (1) Because the PFMV is the purchase price for Expanded HAP, no appraisal of the property...

  6. The Family Adaptation Model: A Life Course Perspective

    Science.gov (United States)

    1990-02-01

    families may vary in their values toward work, family, and community life (Bowen & Janofsky, 1988; Langman , 1987; Wilkinson, 1937). This recognition...1044. Langman , L. (1987). Social stratification. In M. B. Sussman & S. K. Steinmetz (Eds.), Handbook of marriage and the family (pp. 211-249). New York

  7. 75 FR 57385 - Internal Control Over Financial Reporting in Exchange Act Periodic Reports of Non-Accelerated Filers

    Science.gov (United States)

    2010-09-21

    ... COMMISSION 17 CFR Parts 210, 229, and 249 Internal Control Over Financial Reporting in Exchange Act Periodic... effectiveness of the company's internal control over financial reporting. See Release No. 33-8238 (June 5, 2003... audit report an assessment of the issuer's internal control over financial reporting. \\13\\ An...

  8. 78 FR 61208 - Endangered and Threatened Wildlife and Plants; Listing the Blue-throated Macaw

    Science.gov (United States)

    2013-10-03

    ... International (BLI) and the Integrated Taxonomic Information System (ITIS) recognize the blue-throated macaw as...-throated macaws; it also has local, commercial, and ecosystem importance (Kyle 2005, p. 3; Moraes et al... systems and subsequent death (Gaskin 1989, pp. 249, 251, 252). Recently, an examination of tissue...

  9. Convective Heat Transfer in Internal Gas Flows with Temperature-Dependent Properties.

    Science.gov (United States)

    1982-06-30

    effects of variable properties have been provided by Petukhov [1970],specifically for turbulent flow in circular tubes.and by Leontiev o for the...243-249. Leontiev , A. I., 1966. Heat and mass transfer in turbulent boundary layers, Adv. Heat Transfer, 3, pp. 33-100. Leung, E. Y., V. M. Kays and W

  10. Sociolinguistic Variation and Change in British Sign Language Number Signs: Evidence of Leveling?

    Science.gov (United States)

    Stamp, Rose; Schembri, Adam; Fenlon, Jordan; Rentelis, Ramas

    2015-01-01

    This article presents findings from the first major study to investigate lexical variation and change in British Sign Language (BSL) number signs. As part of the BSL Corpus Project, number sign variants were elicited from 249 deaf signers from eight sites throughout the UK. Age, school location, and language background were found to be significant…

  11. Blood lipids and prostate cancer

    DEFF Research Database (Denmark)

    Bull, Caroline J; Bonilla, Carolina; Holly, Jeff M P

    2016-01-01

    Genetic risk scores were used as unconfounded instruments for specific lipid traits (Mendelian randomization) to assess whether circulating lipids causally influence prostate cancer risk. Data from 22,249 prostate cancer cases and 22,133 controls from 22 studies within the international PRACTICAL...

  12. Gclust Server: 110112 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 110112 OSA_Os09g0518500@1 Cluster Sequences Related Sequences(68) 249 no annotation... 1 1.00e-80 14.29 0.0 0.0 0.0 0.0 0.0 Show 110112 Cluster ID 110112 Sequence ID OSA_Os09g0518500@1 Link to c

  13. Dicty_cDB: Contig-U14695-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available om... 44 4.8 1 ( DL005648 ) NUCLEIC ACID PROBES AND NUCLEIC ACID ANALOG PROBES. 4...180 ) Rattus norvegicus clone CH230-249D12, WORKING DRA... 40 5.0 5 ( DL005646 ) NUCLEIC ACID PROBES AND NUCLEIC

  14. 75 FR 64641 - Facilitating Shareholder Director Nominations

    Science.gov (United States)

    2010-10-20

    ... COMMISSION 17 CFR Parts 200, 232, 240, and 249 RIN 3235-AK27 Facilitating Shareholder Director Nominations... rules that the Commission adopted to facilitate the effective exercise of shareholders' traditional state law rights to nominate and elect directors to company boards of directors. We are publishing...

  15. Coping with Workplace Stress: A Multiple-Group Comparison of Female Managers and Clerical Workers.

    Science.gov (United States)

    Long, Bonita C.

    1998-01-01

    A causal model of workplace stress was refined and cross-validated. Multivariate analysis and multiple-group structural equation modeling were used to investigate the effects of social roles on patterns of coping with workplace stress and job satisfaction. Differences found between managers (n=249) and clerical workers (n=214) suggest power and…

  16. Domain Modeling: NP_055062.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available formation of the Tandem PDZ Domains c1u3ba_ chr4/NP_055062.1/NP_055062.1_apo_249-480.pdb swppa 0 ... ...NP_055062.1 chr4 Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Con

  17. Hepatocellular carcinoma and liver cirrhosis TP53 mutation analysis reflects a moderate dietary exposure to aflatoxins in Espírito Santo State, Brazil.

    Science.gov (United States)

    de Carvalho, Fernanda Magri; de Almeida Pereira, Thiago; Gonçalves, Patrícia Lofego; Jarske, Robson Dettmann; Pereira, Fausto Edmundo Lima; Louro, Iuri Drumond

    2013-08-01

    The close relationship between aflatoxins and 249ser TP53 gene mutation (AGG to AGT, Arg to Ser) in hepatocellular carcinoma (HCC) makes this mutation an indirect indicator of dietary contamination with this toxin. We have examined the prevalence of codon 249 TP53 mutation in 41 HCC and 74 liver cirrhosis (without HCC) cases diagnosed at the HUCAM University Hospital in Vitoria, Espírito Santo State, Brazil. DNA was extracted from paraffin sections and from plasma. The mutation was detected by DNA amplification, followed by restriction endonuclease digestion and confirmed by direct sequencing. DNA restriction showed 249ser mutation in 16 HCC and 13 liver cirrhosis, but sequencing confirmed mutations in only 6 HCC and 1 liver cirrhosis. In addition, sequencing revealed 4 patients with mutations at codon 250 (250ser and 250leu) in HCC cases. The prevalence of TP53 mutation was 10/41 (24.3%) in HCC and 1/74 (1.4%) in liver cirrhosis. No relationship between the presence of mutations and the etiology of HCC was observed. TP53 exon 7 mutations, which are related to aflatoxins exposure, were found at 14.6% (249ser), 7.3% (250leu) and 2.4% (250ser) in 41 cases of HCC and 1.4% in 74 liver cirrhosis (without HCC) cases, suggesting a moderate dietary exposure to aflatoxins in the Espírito Santo State, Brazil.

  18. E-Learning in European Higher Education Institutions: Results of a Mapping Survey Conducted in October-December 2013

    Science.gov (United States)

    Gaebel, Michael; Kupriyanova, Veronika; Morais, Rita; Colucci, Elizabeth

    2014-01-01

    The present study on e-learning intends to contribute to closing a data gap and to stimulate the discussion on the further development of national and European policies on the issue and to support its systematic institutional take-up. It draws upon a survey conducted by the European University Association between October and December 2013. 249

  19. 77 FR 47501 - Applications for New Awards; Technical Assistance on State Data Collection, Analysis, and...

    Science.gov (United States)

    2012-08-08

    ... and 618 of IDEA, which may include the development of open source data system software that addresses... Assistance Center Help Desk, email PrivacyTA@ed.gov or call, toll free, 855-249-3072. For more information... information from sources such as SPPs and APRs to assess State data system and data quality needs for the...

  20. Chloroguanide metabolism in relation to the efficacy in malaria prophylaxis and the S-mephenytoin oxidation in Tanzanians

    DEFF Research Database (Denmark)

    Skjelbo, E; Mutabingwa, T K; Bygbjerg, Ib Christian;

    1996-01-01

    S-Mephenytoin and chloroguanide (proguanil) oxidation was studied in 216 tanzanians. The mephenytoin S/R ratio in urine ranged from 0.9, were arbitrarily defined as poor metabolizers of mephenytoin. The chloroguanide/cycloguanil ratio ranged from 0.82 to 249. There was a significant correlation b...

  1. CONTRACTION CHARACTERISTICS AND MYOSIN HEAVY-CHAIN COMPOSITION OF RABBIT MASSETER MOTOR UNITS

    NARCIS (Netherlands)

    KWA, SHS; WEIJS, WA; JUCH, PJW

    1995-01-01

    1. We studied isometric twitch peak force (TPF) and twitch contraction time (TCT) of 249 motor units of the masseter muscle in 41 rabbits after extracellular electrical stimulation of single trigeminal motoneurons in the brain stem. In 41 of these units we determined the amount of tension decrease d

  2. 48 CFR 2152.070 - Applicable clauses.

    Science.gov (United States)

    2010-10-01

    ... Asset Reversions 52.215-16Facilities Capital Cost of Money 52.215-17Waiver of Facilities Capital Cost of...-21Prohibition of Segregated Facilities 52.222-22Previous Contracts and Compliance Reports 52.222-25Affirmative...-63Preference for U.S.-Flag Air Carriers 52.249-2Termination for Convenience of the Government (Fixed Price)...

  3. Evaluation of Purine Salvage as a Chemotherapeutic Target in the Plasmodium Yoelli Rodent Model

    Science.gov (United States)

    2006-03-01

    Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA c Instituto de Medicina Molecular, Universidade de Lisboa, Av. Prof. Egas...P. berghei were not accessible at the time of ur trials. A.M. Jongco et al. / Molecular & Biochemical Parasitology 146 (2006) 242–250 249 Fig. 4

  4. 75 FR 82005 - Agency Information Collection Activities; Proposed Collection; Comment Request; Hazardous Waste...

    Science.gov (United States)

    2010-12-29

    ... [Federal Register Volume 75, Number 249 (Wednesday, December 29, 2010)] [Notices] [Pages 82005-82007] [FR Doc No: 2010-32851] ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-RCRA-2010-0833, FRL-9245-5... Resource Conservation and Recovery. [FR Doc. 2010-32851 Filed 12-28-10; 8:45 am] BILLING CODE 6560-50-P...

  5. Reference: AGCBOXNPGLB [PLACE

    Lifescience Database Archive (English)

    Full Text Available AGCBOXNPGLB Sato F, Kitajima S, Koyama T, Yamada Y Ethylene-induced gene expression... of osmotin-like protein, a neutral isoform of tobacco PR-5, is mediated by the AGCCGCC cis-sequence Plant Cell Physiol 37: 249-255 (1996) PubMed: 8673338; ...

  6. AcEST: DK962740 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ocara canis G... 249 9e-66 sp|P50880|RL3_CAEEL 60S ribosomal protein L3 OS=Caenorha...-67 sp|P59671|RL3_NEUCR 60S ribosomal protein L3 OS=Neurospora crass... 251 2e-66 sp|P49149|RL3_TOXCA 60S ribosomal protein L3 OS=Tox

  7. Children with Anatomical Congenital Anomalies; a Portrait Follow-up over five years

    NARCIS (Netherlands)

    P. Mazer (Petra); S.J. Gischler (Saskia)

    2008-01-01

    textabstractAnnually some 5.000 newborns (2 - 3% of all births) in the Netherlands present with major anatomical congenital anomalies.140,395 The causes of most of these are still unknown. So far, genetic or chromosomal causes have been implicated in 13 - 14% of all anomalies,17,120,214,249,337 and

  8. Relevance of Radiocaesium Interception Potential (RIP) on a worldwide scale to assess soil vulnerability to 137Cs contamination

    NARCIS (Netherlands)

    Vandebroek, L.; Hees, Van M.; Delvaux, B.; Spaargaren, O.; Thiry, Y.

    2012-01-01

    The extent of radiocaesium retention in soil is important to quantify the risk of further foodchain contamination. The Radiocaesium Interception Potential (RIP – Cremers et al., 1988, Nature 335, 247–249) is an intrinsic soil parameter which can be used to categorize soils or minerals in terms of th

  9. Myths and Misconceptions in Popular Psychology: Comparing Psychology Students and the General Public

    Science.gov (United States)

    Furnham, Adrian; Hughes, David J.

    2014-01-01

    This study examined the prevalence of psychological myths and misconceptions among psychology students and within the general population. In total, 829 participants completed a 249-item questionnaire designed to measure a broad range of psychological myths. Results revealed that psychological myths and misconceptions are numerous and widely held.…

  10. Context effect in assimilation and contrast

    NARCIS (Netherlands)

    Weert, C.M.M. de; Koning, A.R.; Lier, R.J. van

    2005-01-01

    We have systematically studied the change of lightness appearance in an ambiguous visual pattern. Fuchs (1923 Zeitschrift für Psychologie 92 249 - 325) found that differently coloured parts assimilate, whereas Agostini et al (1993 Perception 22 263 - 272) described the opposite effect: contrast betw

  11. Data of evolutionary structure change: 1OZHA-1UPCD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1OZHA-1UPCD 1OZH 1UPC A D VRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLL...>LYS CA 249 VAL CA 284 1UPC D... 1UPCD LLGSSEGIDTPNPP HHH ... ILE CA 324 ASP CA 254 1UPC D 1UPCD GVVADGWQKAAD

  12. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review

    NARCIS (Netherlands)

    Zimmermann, M.B.

    2009-01-01

    The World Health Organization (WHO) recently increased their recommended iodine intake during pregnancy from 200 to 250 µg/d and suggested that a median urinary iodine (UI) concentration of 150-249 µg/L indicates adequate iodine intake in pregnant women. Thyrotropin concentrations in blood collected

  13. 17 CFR 240.14d-1 - Scope of and definitions applicable to Regulations 14D and 14E.

    Science.gov (United States)

    2010-04-01

    ... the Commission on Form CB (§ 249.480 of this chapter) by the first business day after publication or... person specified in § 240.14d-9(d), provides any journalist with access to its press conferences held... proposed tender offer is discussed, if: (1) Access is provided to both U.S. and foreign journalists; and...

  14. Legislation by Hypothesis: The Case of Task-Based Instruction

    Institute of Scientific and Technical Information of China (English)

    Michael Swan

    2010-01-01

    @@ (Continued from last issue) 4.5 Other sources: pre-and post-task work, materials, the teacher Pre-teaching is widely cited as a way of priming on-line noticing (Schmidt 1990, 2001) and more generally as a source of new language (Skehan 1998:137; Skehan and Foster 2001: 199; R.Ellis 2003:249).

  15. Gclust Server: 62015 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 62015 DPTM_GSPATP00018828001 Cluster Sequences Related Sequences(1) 249 no annotati...on 2 1.00e-45 0.0 11.11 0.0 0.0 0.0 0.0 Show 62015 Cluster ID 62015 Sequence ID DPTM_GSPATP00018828001 Link

  16. AcEST: DK945439 [AcEST

    Lifescience Database Archive (English)

    Full Text Available whole genome... 137 3e-31 tr|Q6ZZK5|Q6ZZK5_ACTTI Short chain dehydrogenase OS=Actinoplanes... 134 3e-30 tr|A...ASVVGFLASDGGEWVNGQVVRVNGGY 249 >tr|Q6ZZK5|Q6ZZK5_ACTTI Short chain dehydrogenase OS=Actinoplanes teichomycet

  17. Meditation or medication? Preventing relapse in recurrent depression

    NARCIS (Netherlands)

    Huijbers, M.J.

    2017-01-01

    In this study, 249 patients with recurrent depression participated in mindfulness-based cognitive therapy (MBCT), a group training that improves skills to cope with difficult thoughts and emotions. Afterwards, half of the group was asked to stop taking their antidepressants, whereas the other half c

  18. Dieting, Dietary Restraint, and Binge Eating Disorder among Overweight Adolescents in Turkey

    Science.gov (United States)

    Bas, Murat; Bozan, Nuray; Cigerim, Nevin

    2008-01-01

    The purpose of this study was to determine the relationship among dieting, dietary restraint, disinhibition, hunger, and binge eating among overweight adolescent girls. Participants were 743 overweight adolescent girls between 16 and 19 years of age. The mean BMI was 24.9 [+ or -] 0.8 kg/[m[superscript 2] in the low-restraint group and 25.1 [+ or…

  19. "Euroopa viimased metslased" : eestlased saksa koloniaaldiskursis 1770-1870 / Ulrike Plath

    Index Scriptorium Estoniae

    Plath, Ulrike

    2008-01-01

    Eesti ja läti pärisorjade võrdlemisest metslastega, eestlaste "eksoteerimisest", põhjuseks keelesugulus saamide ja samojeedidega. Pikemalt Johann Georg Kohli teosest "Die Völker Europas" (1868). Baltisaksa koloniaaldiskursi kujunemisest 19. sajandil. Sisaldab bibliograafiat. Autorist lk. 249

  20. Self-Efficacy, Gender and Trait Anxiety as Moderators of Test Anxiety

    Science.gov (United States)

    Onyeizugbo, Euckay U.

    2010-01-01

    Introduction: Test anxiety inhibits students from performing according to their full potential in academic setting. Objectives: This study investigated self-efficacy, gender and trait anxiety as moderators of test anxiety. Method: Two hundred and forty nine (249) psychology majors drawn from a university in Eastern Nigeria participated in the…

  1. VIMOS-VLT and Spitzer observations of a radio galaxy at z=2.5

    NARCIS (Netherlands)

    Villar-Martin, M; Sanchez, SF; De Breuck, C; Peletier, R; Vernet, J; Rettura, A; Seymour, N; Humphrey, A; Stern, D; Alighieri, SD; Fosbury, R

    2006-01-01

    We present: (i) a kinematic and morphological study of the giant Ly alpha nebula associated with the radio galaxy MRC 2104-242 (z = 2.49) based on integral field spectroscopic Visible Multiobject Spectrograph (VIMOS) data from the Very Large Telescope (VLT), and (ii) a photometric study of the host

  2. Data of evolutionary structure change: 1DFFA-3CPMA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1DFFA-3CPMA 1DFF 3CPM A A -----SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDM...line> 3CPM A 3CPMA THR CA 218 GLY CA 249 ILE CA 245 3CPM... A 3CPMA IKKYSDKLVPFILE CA 305 ARG CA 316 GLN CA 241 3CPM

  3. SAE Scope and Student Achievement in Agribusiness and Natural Resources Education.

    Science.gov (United States)

    Arrington, Larry R.; Cheek, Jimmy G.

    1990-01-01

    Study determined relationship between scope of supervised agricultural experience (SAE) as measured by total income and Productive Man Work Units (PMWU) and level of achievement of students enrolled in vocational agriculture classes in Florida. Responses from 98 Applied Principles and 249 Fundamentals students found low SAE participation and…

  4. 75 FR 82073 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-12-29

    ... [Federal Register Volume 75, Number 249 (Wednesday, December 29, 2010)] [Notices] [Page 82073] [FR Doc No: 2010-32855] DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled... registered as a bulk manufacturer of the basic classes of controlled substances listed in schedules I and...

  5. Kala töötlemine : [andmeid aastatest 1995-2004] / Maarja Purik

    Index Scriptorium Estoniae

    Purik, Maarja

    2005-01-01

    Ilmunud ka: Agriculture and the development of rural life : overview 2004/2005. - Tallinn, 2005, lk. 49-52. Kalatöötlemise osatähtsus toiduainetööstuses moodustas 2004. a. 11,9% ja ekspordis 24,9%. Tabelid. Diagrammid

  6. Morphological features of Co-rich manganese deposits and their relation to seabed slopes

    Digital Repository Service at National Institute of Oceanography (India)

    Yamazaki, T.; Sharma, R.

    -rich(manganesecrustsaroundMarcusIsland.MarineSciencesMonthly19:209] 214in )Japanese.Morgan,C.L.,R.O.Mahan,A.Malahof,andJ.C.Wiltshire.198.MicrotopographyofCrosSeamount.MarineMining7:249] 269. Pichocki,C.,andM.Hofert.1987.CharacteristicsofCo-richferomanganesenodulesandcrustssampledinFrench...

  7. Data of evolutionary structure change: 1ALCA-1LMAA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ALCA-1LMAA 1ALC 1LMA A A KQFTKCELSQNL--YDIDGYGRIALPELICTMFHTSGYD...yChain> 1LMA A 1LMA...55 ASP CA 290 1LMA A 1LMA...U CA 249 GLU CA 193 GLN CA 219 TRP CA 312 1LMA... A 1LMAA NRCKGT

  8. Defense Conference on Nondestructive Testing (28th), 27-29 November 1979

    Science.gov (United States)

    1979-11-29

    Frankford Arsenal personnel established a library of shell illustrating various types and degrees of interior cavity defects and conducted training of...663-8411 AV: 249-8411 SA-ALC/MMETP, Kelly AFB, TX 78241 (512)925-8735 AV: 945-8735 Norman H. GEISEL Naval Air Test Center, Systems Stephen D. HART

  9. Attention-Deficit, Fear and Aggression in Iranian Preschool Students with Regard to Gender Differences

    Science.gov (United States)

    Sheikhzade, Mostafa; Assemi, Arezoo

    2013-01-01

    The cause of most adult psychopathologies or behavioural disorders can be traced back to childhood. In this study, we examine the attention-deficit, fear and aggression in Iran's preschool students in Oshnaviye city. In this analytical-descriptive study, 50 students were selected through stratified sampling method from 249 students. Data were…

  10. MELD: A Logical Approach to Distributed and Parallel Programming

    Science.gov (United States)

    2012-03-01

    USA: ACM, 1974, pp. 249–264. [14] M. Isard , M. Budiu, Y. Yu, A. Birrell, and D. Fetterly, “Dryad: Distributed data-parallel programs from sequential...TR-2006-140. [Online]. Available: http://budiu.info/work/eurosys07.pdf [15] Y. Yu, M. Isard , D. Fetterly, M. Budiu, Ú . Erlingsson, P. K. Gunda

  11. Bleeding Time, Volume of Shed Blood Collected at the Bleeding Time Site, and the Peripheral Venous Hematocrit.

    Science.gov (United States)

    2007-11-02

    The bleeding time. Prog in Hemostasis and Thrombosis, NY, Grune-Stratton 2:249-271,1974. 2. The bleeding time. The Lancet 1991;337:1447-1448. 3...aggregation. The Lancet 1984;1409-1410. 29. The bleeding-time and the haematocrit. The Lancet May 4; 1984;997-998. 30. Turrito VT,Weiss HJ: Red blood

  12. Is Motor Performance in 5.5-Year-Old Children Associated with the Presence of Generalized Joint Hypermobility?

    NARCIS (Netherlands)

    Boer, R.M. de; Vlimmeren, L.A. van; Scheper, M.C.; Sanden, M.W. van der; Engelbert, R.H.

    2015-01-01

    OBJECTIVE: To determine the prevalence of generalized joint hypermobility (GJH) in Dutch children aged 5.5 years, and to examine the association between GJH and motor performance and development over time. STUDY DESIGN: A prospective cohort of 249 children was recruited. GJH was assessed with the Be

  13. Final Report of the Evaluation of the 1969-1970 Benjamin Franklin Cluster Program: Programs and Patterns for Disadvantaged High School Students. ESEA Title I.

    Science.gov (United States)

    Hoffman, Louis J.

    The Cluster Program at Benjamin Franklin High School, funded under Title I of the 1965 Elementary Secondary Education Act, is designed to be a school within a school in which 249 ninth grade students attend classes in two separate clusters. Each cluster is formulated such that all students receive instruction from five teachers in classes whose…

  14. Generation of a Saturated Genetic Recombination Map for Avocado (Persea americana)

    Science.gov (United States)

    Two large mapping populations of avocado consisting of 1582 trees were genotyped with 5050 SNP markers from transcribed genes using an Illumina Infinium SNP chip. A Florida mapping population consisted of 527 progeny from 'Tonnage' x 'Simmonds' and 249 from 'Simmonds' x 'Tonnage'. A California map...

  15. 76 FR 2287 - Security-Based Swap Data Repository Registration, Duties, and Core Principles; Correction

    Science.gov (United States)

    2011-01-13

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION 17 CFR Parts 240 and 249 RIN 3235-AK79 Security-Based Swap Data Repository Registration, Duties, and Core Principles; Correction Correction In proposed rule document C1-2010-29719 beginning on...

  16. The Needs Assessment of Implementing NTIS into the VTAE System. Final Report.

    Science.gov (United States)

    Rust, Leland

    A study investigated the competencies required to use the National Technical Information Service (NTIS) and the perceived need for its use for curriculum and instructional improvement in the Wisconsin Vocational, Technical, and Adult Education (VTAE) system. A representative sample (N=249) of VTAE instructors and staff was selected for the survey…

  17. Applications of holography. Citations from the NTIS data base

    Science.gov (United States)

    Carrigan, B.

    1980-05-01

    The bibliography covers studies on the applications of holography in such areas as photograping high-speed particles, nondestructive testing of material defects, strain analysis, microscopy, interferometry, vibration measurement, and medical diagnosis. This updated bibliography contains 249 abstracts, none of which are new entries to the previous edition.

  18. Hot wire anemometry. Citations from the NTIS data base

    Science.gov (United States)

    Habercom, G. E., Jr.

    1980-08-01

    Citations include principles; calibrating; circuit diagrams; flow measurement; hypersonic, supersonic, transonic, and subsonic characteristics; boundary layer studies; turbulence; jet, pipe, and tunnel flow; mathematical models; wind tunnel model tests, airport structure simulation; mass transfer and flow stability; probe modifications; flow about geometric forms; flow patterns; and related topics. This updated bibliography contains 249 citations, 28 of which are new entries to the previous edition.

  19. Further Enrichment and Analysis of Rat CFU-s

    Science.gov (United States)

    1990-01-01

    consistent With CFU-s having been characterized as non-proliferating cells [24]. The hemato - logical function of the 0x720, Ox22-, and W3/13b is, at the...Exp Hematol 1988;16:245-249. 17 Harris RA, Hogarth PM, Wadeson L, Collins P, McKenzie IFC, Penington DG. An antigenic difference between cells

  20. Data of evolutionary structure change: 1ALCA-1VEDA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ALCA-1VEDA 1ALC 1VED A A KQFTKCELSQNL--YDIDGYGRIALPELICTMFHTSGYD...CA 233 THR CA 295 GLU CA 388 TYR CA 428 1VED... A 1VEDA ASP CA 290 1VED A 1VED... CA 249 GLU CA 193 GLN CA 219 TRP CA 312 1VED

  1. Glycerin Reformation in High Temperature and Pressure Water

    Science.gov (United States)

    2012-01-01

    Ravella, A., Eds.), pp 249-281, Kluwer Academic Publishers, Dordrecht, The Netherlands. 168. Contadini, J. F., Diniz, C. V., Sperling, D., and Moore , R...reforming of glycerol, Bioresource Technology 100, 3540-3547. 253. Iulianelli, A., Longo, T., Liguori, S., and Basile , A. (2010) Production of

  2. AcEST: DK958333 [AcEST

    Lifescience Database Archive (English)

    Full Text Available lathrin Coat Assembly protein (... 249 6e-65 tr|Q5N9S2|Q5N9S2_ORYSJ Clathrin-associated protein unc-101-like... 522 MDFGYPQYTEAKILSEFIKTDAY 590 MDFGYPQYTEA+ILSEFIKTDAY Sbjct: 121 MDFGYPQYTEARILSEFIKTDAY 143 >tr|Q5N9S2|Q5N9S2_ORYSJ Clathrin-

  3. Book Review

    Directory of Open Access Journals (Sweden)

    Dedy Darnaedi

    2012-12-01

    Full Text Available B.S. Parris, R. Kiew, R.C.K. Chung, L.G. Saw  & E. Soepadmo (eds. 2010. Flora of Peninsular Malaysia, Series I. Ferns and Lycophytes. Vol  1.  Malayan Forest Records No. 48. Forest Research Institute Malaysia, Ministry of Natural Resources and Environment, Malaysia, 249 pp. Price: RM80/USD60. 

  4. Characterisation of antioxidant and antiproliferative acidic polysaccharides from Chinese wolfberry fruits

    NARCIS (Netherlands)

    He, N.W.; Yang, X.B.; Jiao, Y.D.; Tian, L.; Zhao, Y.

    2012-01-01

    Wolfberry fruit polysaccharides (WFPs) were isolated by hot-water extraction and ethanol precipitation. With HPLC analysis, WFPs were for the first time identified as acidic polysaccharides with galacturonic acid being the main component monosaccharide (24.9%), followed by galactose (21.3%), arabino

  5. GETDB: 103764 [GETDB

    Lifescience Database Archive (English)

    Full Text Available nstitute of Genetics. CyO Link to clone table - 1 726 Link to cluster table 726 1 Request - cns + pns - sg, cns - lethal - comment...1:A, comment2:49F9 - - - - Show 103764 DGRC Number 103764 L...gal sg, cns Adult GFP - Lethality lethal Also known as - Original Comments comment1:A, comment

  6. Evaluation of pulsatility index and diameter of the jugular vein and superficial body temperature as physiological indices of temperament in weaned beef calves: relationship with serum cortisol concentrations, rectal temp..

    Science.gov (United States)

    The relationship between temperament, pulsatility index and diameter of the jugular vein, and body temperature was assessed in Angus crossbred calves (262±24.9 days old). Temperament scores were used to classify calves as calm (n=31), intermediate (n=32), or temperamental (n=28). Blood samples were ...

  7. "Sa oled mul teine" : teisesusest eesti kultuuri eneseanalüüsis / Aare Pilv

    Index Scriptorium Estoniae

    Pilv, Aare, 1976-

    2008-01-01

    Kolmest eesti kultuuri eneseanalüüsi kontseptsioonist: "katkestus" (Hasso Krull), "eksistentsialistlik absurdiprojekt" (Jaan Undusk), "enesekolonisatsioon" (Tiit Hennoste). Poleemikat T. Hennoste enesekolonisatsiooni teooriaga (olulisim tekst selle kohta on 2006. a. avaldatud artikkel "Noor-Eesti kui lõpetamata enesekoloniseerimisprojekt"). Sisaldab bibliograafiat. Autorist lk. 249

  8. The work of Powers and Brownyard revisited: Part 2

    NARCIS (Netherlands)

    Brouwers, H.J.H.

    2005-01-01

    Powers and Brownyard [T.C. Powers, T.L. Brownyard, Studies of the physical properties of hardened Portland cement paste, Bull. 22, Res. Lab. of Portland Cement Association, Skokie, IL, U.S., 1948 reprinted from J. Am. Concr. Inst. (Proc.), 43, 1947, pp. 101–132, pp. 249–336, pp. 469–505, pp. 549–602

  9. The work of Powers and Brownyard revisited: Part 1

    NARCIS (Netherlands)

    Brouwers, H.J.H.

    2004-01-01

    Powers and Brownyard [Studies of the physical properties of hardened Portland cement paste. Bull. 22, Res. Lab. of Portland Cement Association, Skokie, IL, U.S. J. Am. Concr. Inst. (Proc.), 43 (1947) 101–132, 249–336, 469–505, 549–602, 669–712, 845–880, 933–992 (reprint)] were the first to systemati

  10. Results of a Multisite Survey of U.S. Psychiatry Residents on Education in Professionalism and Ethics

    Science.gov (United States)

    Jain, Shaili; Dunn, Laura B.; Warner, Christopher H.; Roberts, Laura Weiss

    2011-01-01

    Objective: The authors assess the perspectives of psychiatry residents about the goals of receiving education in professionalism and ethics, how topics should be taught, and on what ethical principles the curriculum should be based. Method: A written survey was sent to psychiatry residents (N = 249) at seven U.S. residency programs in Spring 2005.…

  11. AcEST: BP914857 [AcEST

    Lifescience Database Archive (English)

    Full Text Available UMAN Helicase SRCAP OS=Homo sapiens GN=SRCAP PE... 48 2e-05 sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophil...MLAE 199 + +K Q LE +KKALD HLDF+VGQTE+YS +L++ Sbjct: 213 VQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domin

  12. AcEST: BP919933 [AcEST

    Lifescience Database Archive (English)

    Full Text Available case SRCAP OS=Homo sapiens GN=SRCAP PE... 66 1e-10 sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanog...QFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melano

  13. AcEST: BP920718 [AcEST

    Lifescience Database Archive (English)

    Full Text Available RS2|SRCAP_HUMAN Helicase SRCAP OS=Homo sapiens GN=SRCAP PE... 76 8e-14 sp|Q9NDJ2|DOM_DROME Helicase domino O... HLDF+VGQTE+YS +L++ Sbjct: 191 LRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino

  14. AcEST: BP912286 [AcEST

    Lifescience Database Archive (English)

    Full Text Available OS=Homo sapiens GN=SRCAP PE... 72 3e-12 sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanogaster G... ...VGQTE+YS +L++ Sbjct: 194 IASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino

  15. AcEST: BP920558 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ue sp|Q6ZRS2|SRCAP_HUMAN Helicase SRCAP OS=Homo sapiens GN=SRCAP PE... 81 3e-15 sp|Q9NDJ2|DOM_DROME Helicase domino...FKQQSRLEEKRKKALDLHLDFIVGQTEKYSD 245 Query: 347 MLAE 336 +L++ Sbjct: 246 LLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino

  16. AcEST: BP915811 [AcEST

    Lifescience Database Archive (English)

    Full Text Available N=SRCAP PE... 48 3e-05 sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanogaster G... 44 3e-04 sp|P4996... 213 VQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanogast

  17. AcEST: BP920230 [AcEST

    Lifescience Database Archive (English)

    Full Text Available .. 76 5e-14 sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanogaster G... 70 3e-12 sp|Q9NEL2|SSL1_CAEE...IVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanogaster GN=dom PE=1 SV=2 Length =

  18. 17 CFR 239.13 - Form S-3, for registration under the Securities Act of 1933 of securities of certain issuers...

    Science.gov (United States)

    2010-04-01

    ... stock, as of a date within 60 days prior to the date of filing. See the definition of affiliate in... are quoted on the automated quotation system of a national securities association. In addition, Form S... statements were included in the registrant's latest filing on Form 20-F (17 CFR 249.220f). In complying...

  19. Stable fetal hemodynamics measured by Doppler flow after initiation of anti-hypertensive treatment with methyldopa in pregnant women with diabetes

    DEFF Research Database (Denmark)

    Pedersen, Berit Woetmann; Ringholm, Lene; Damm, Peter

    2016-01-01

     mg three times daily) was performed and the cerebro-placental ratio (CPR) was calculated. RESULTS: Methyldopa treatment was initiated at median 249 (range 192-260) gestational days, mainly due to gestational hypertension (n = 7). Blood pressure declined from 142 (112-156)/92 (76-103) mmHg before...

  20. Child maltreatment and trajectories of personality and behavioral functioning: Implications for the development of personality disorder

    OpenAIRE

    2009-01-01

    This study investigated the longitudinal impact of maltreatment parameters on personality processes and maladjustment and prospective relationships between personality trajectory classes and subsequent maladjustment outcomes. The sample involved maltreated (n = 249) and nonmaltreated (n = 200) children followed longitudinally between ages 6 – 10. Growth mixture modeling indicated multifinality in personality development depending on the risk status (i.e., maltreated vs. nonmaltreated). Two tr...

  1. 78 FR 4766 - Adoption of Updated EDGAR Filer Manual

    Science.gov (United States)

    2013-01-23

    ... COMMISSION 17 CFR Parts 232, 239, 249, 269, 274 Adoption of Updated EDGAR Filer Manual AGENCY: Securities and...) Filer Manual and related rules to reflect updates to the EDGAR system. The revisions are being made...: Effective Date: January 23, 2013. The incorporation by reference of the EDGAR Filer Manual is approved...

  2. Hemoglobin, Growth, and Attention of Infants in Southern Ethiopia

    Science.gov (United States)

    Aubuchon-Endsley, Nicki L.; Grant, Stephanie L.; Berhanu, Getenesh; Thomas, David G.; Schrader, Sarah E.; Eldridge, Devon; Kennedy, Tay; Hambidge, Michael

    2011-01-01

    Male and female infants from rural Ethiopia were tested to investigate relations among hemoglobin (Hb), anthropometry, and attention. A longitudinal design was used to examine differences in attention performance from 6 (M = 24.9 weeks, n = 89) to 9 months of age (M = 40.6 weeks, n = 85), differences hypothesized to be related to changes in iron…

  3. Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe.

    Science.gov (United States)

    Annan, Augustina; Baldwin, Heather J; Corman, Victor Max; Klose, Stefan M; Owusu, Michael; Nkrumah, Evans Ewald; Badu, Ebenezer Kofi; Anti, Priscilla; Agbenyega, Olivia; Meyer, Benjamin; Oppong, Samuel; Sarkodie, Yaw Adu; Kalko, Elisabeth K V; Lina, Peter H C; Godlevska, Elena V; Reusken, Chantal; Seebens, Antje; Gloza-Rausch, Florian; Vallo, Peter; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix

    2013-03-01

    We screened fecal specimens of 4,758 bats from Ghana and 272 bats from 4 European countries for betacoronaviruses. Viruses related to the novel human betacoronavirus EMC/2012 were detected in 46 (24.9%) of 185 Nycteris bats and 40 (14.7%) of 272 Pipistrellus bats. Their genetic relatedness indicated EMC/2012 originated from bats.

  4. Belongingness and Suicidal Ideation in College Students

    Science.gov (United States)

    Ploskonka, Rachel A.; Servaty-Seib, Heather L.

    2015-01-01

    Objective: In this study, the relationships between 3 specific domains of belongingness (ie, family, peers, and academic institution) were examined with respect to suicidal ideation. Participants: A sample (N = 249) of undergraduate students was recruited from a large, midwestern university during the Spring 2013 semester. Methods: Multiple…

  5. 77 FR 76588 - Request for Proposal Platform Pilot

    Science.gov (United States)

    2012-12-28

    ... [Federal Register Volume 77, Number 249 (Friday, December 28, 2012)] [Notices] [Pages 76588-76590... government buys web design and related technology services from small businesses for acquisitions valued at... functionality of RFP-EZ, as described at www.sba.gov/rfpez and highlighted in this notice. Responses to...

  6. QTL Information Table: 504 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qSD-5 Physiological trait Germination/dormancy Seed dormancy RFLP C)Interval BIL Ni...pponbare Kasalath A R3166 C249 R1838 pha Miura, K., Lin, Y., Yano, M., and Nagamine, T. (2002). Mapping quantitative trait

  7. Fighting Afghanistan’s Opium Dependency as a Means of Disrupting Al Qaeda’s Illicit Funding

    Science.gov (United States)

    2006-06-16

    taking a quick survey of the multidecade effort to combat the Latin American cocaine crisis one can better understand how this translates into the CN...on 2 December 1993, in a shootout with soldiers from the Bloque de Búsqueda, or Search Bloc (Bowden 2001, 249). Some of these successful programs

  8. Numerical Computation of Large Amplitude Internal Solitary Waves,

    Science.gov (United States)

    1981-03-20

    provide adequate resolution. All computations were performed on a CDC Cyber 176 computer, and it takes slightly less than one CPU second to obtain a...H. Segur , Lgn Internal Waves in Fluids of Great Depth, Studies in Applied Math., 62 (1980), pp. 249-262. [3] E. Allgower and K. Georg, Simlicial -and

  9. Music during Lectures: Will Students Learn Better?

    Science.gov (United States)

    Dosseville, Fabrice; Laborde, Sylvain; Scelles, Nicolas

    2012-01-01

    We investigated the influence of music during learning on the academic performance of undergraduate students, and more particularly the influence of affects induced by music. Altogether 249 students were involved in the study, divided into a control group and an experimental group. Both groups attended the same videotaped lecture, with the…

  10. QTL Information Table: 502 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qSBR-3 Resistance or Tolerance Sheath blight resistance Sheath blight response RFLP C)Interval DHL ZYQ8 Ji...ngxi 17 G249 G164 pha Kunihiro, Y., Qian, Q., Sato, H., Teng, S., Zeng, D.L., Fujimot

  11. Sex Differences in Dichotic Listening

    Science.gov (United States)

    Voyer, Daniel

    2011-01-01

    The present study quantified the magnitude of sex differences in perceptual asymmetries as measured with dichotic listening. This was achieved by means of a meta-analysis of the literature dating back from the initial use of dichotic listening as a measure of laterality. The meta-analysis included 249 effect sizes pertaining to sex differences and…

  12. Attention-Deficit, Fear and Aggression in Iranian Preschool Students with Regard to Gender Differences

    Science.gov (United States)

    Sheikhzade, Mostafa; Assemi, Arezoo

    2013-01-01

    The cause of most adult psychopathologies or behavioural disorders can be traced back to childhood. In this study, we examine the attention-deficit, fear and aggression in Iran's preschool students in Oshnaviye city. In this analytical-descriptive study, 50 students were selected through stratified sampling method from 249 students. Data were…

  13. 75 FR 64120 - Technical Amendments to Forms N-CSR and N-SAR in Connection With the Comprehensive Iran Sanctions...

    Science.gov (United States)

    2010-10-19

    ... COMMISSION 17 CFR Parts 249 and 274 Technical Amendments to Forms N-CSR and N-SAR in Connection With the... adopting technical amendments to Forms N-CSR and N-SAR under the Securities Exchange Act of 1934 and the... Securities and Exchange Commission (``Commission'') is adopting technical amendments to Form N-CSR \\1\\...

  14. 47 CFR 73.202 - Table of Allotments.

    Science.gov (United States)

    2010-10-01

    ..., 299C3 Hotchkiss 258C3 Hugo 222A Lake City 247A Olathe *270C2, *293C Orchard Mesa 249C3 Silverton 281A..., 286C2 Santa Anna 282A Savoy 297A Shamrock 271A Sheffield 224C2 Silverton 252A Smiley 280A Snyder...

  15. Gclust Server: 91938 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 91938 OTAU_23983 Cluster Sequences Related Sequences(249) 402 estExt_fgenesh1_pg.C_...Chr_08.00010053 1 1.00e-99 14.29 0.0 0.0 0.0 0.0 0.0 Show 91938 Cluster ID 91938 Sequence ID OTAU_23983 Link

  16. Investigation of Problem Solving Ability of Students in School of Physical Education and Sports (Kafkas University Sample)

    Science.gov (United States)

    Ozmutlu, Ilker

    2014-01-01

    The aim of this research is to examine the problem solving abilities of School of Physical Education and Sports students. To achieve this aim, in the academic year 2013-2014, a research group did a study of 433 students of the School of Physical Education and Sports, Kafkas University. This sample consisted of 184 female and 249 male students.…

  17. Multifractal Internet Traffic Model and Active Queue Management

    Science.gov (United States)

    2003-01-01

    there have been some modifications such as Stabilized RED ( SRED ) [93], Flow RED (FRED) [94], Weighted RED [95], Random Early Marking (REM) [38], BLUE...La, “Nonlinear instabilities in TCP-RED,” in Proceedings of INFOCOM, 2002, pp. 249 –258. [93] T.J. Ott, T.V. Lakshman, and L.H. Wong, “ SRED : Stabilized

  18. A DDC Bibliography on Computers in Information Sciences. Volume I. Information Sciences Series.

    Science.gov (United States)

    Defense Documentation Center, Alexandria, VA.

    The unclassified and unlimited bibliography compiles references dealing specifically with the role of computers in information sciences. The volume contains 249 annotated references grouped under two major headings: Time Shared, On-Line, and Real Time Systems, and Computer Components. The references are arranged in accesion number (AD-number)…

  19. MOOC & B-Learning: Students' Barriers and Satisfaction in Formal and Non-Formal Learning Environments

    Science.gov (United States)

    Gutiérrez-Santiuste, Elba; Gámiz-Sánchez, Vanesa-M.; Gutiérrez-Pérez, Jose

    2015-01-01

    The study presents a comparative analysis of two virtual learning formats: one non-formal through a Massive Open Online Course (MOOC) and the other formal through b-learning. We compare the communication barriers and the satisfaction perceived by the students (N = 249) by developing a qualitative analysis using semi-structured questionnaires and…

  20. 75 FR 79320 - Security-Based Swap Data Repository Registration, Duties, and Core Principles

    Science.gov (United States)

    2010-12-20

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION 17 CFR Parts 240 and 249 RIN 3235-AK79 Security-Based Swap Data Repository Registration, Duties, and Core Principles Correction In proposed rule document 2010-29719 beginning on page 77306 in...

  1. Effects of Chemistry and Processing on the Fracture Related Properties of P/M Alloy CT91.

    Science.gov (United States)

    1985-08-01

    p. 245. 141. R.O. Ritchie, mEnvironmentally-Sensitive Fracture of Engineering Materials", Z.A. Foroylis, Ed, TMS-AIME, 1978. 142. J.F. Knott and A.C...AFWAL/ FIB , Personal Communication, 1979. 248. G. Chanani, Northrop Corporation, Personal Communication, 1979. 249. D. R. Holloway, "X-Ray Diffraction

  2. 17 CFR 240.12g-4 - Certifications of termination of registration under section 12(g).

    Science.gov (United States)

    2010-04-01

    ... Commission on Form 15 (17 CFR 249.323) that the class of securities is held of record by: (1) Less than 300... on the last day of each of the issuer's most recent three fiscal years. (b) The issuer's duty to file... suspension resulted from the issuer's merger into, or consolidation with, another issuer or issuers,...

  3. Dollar Summary of Federal Supply Classification and Service Category by Company, FY83, Part 4 (AA92-N063).

    Science.gov (United States)

    1983-01-01

    249 MISSOURI UNIVERSITY OF MISSOURI ARMY RDTE/OTHER MEDICAL 29- MITRE CORP VIRGINIA ARMY ROTE/OTHER MEDICAL 64 MOLECULAR GENETICS INC MINNESOTA ARMY...MISCELLANEOUS EQUIP 136 INSFALACIONES TECNICAS S A PANAMA ARMY MAINT-REPAIR OF EQ/MISCELLANEOUS EQUIP 78 INTERNATIONAL BUSINESS MACHINE CO VIRGINIA ARMY

  4. Impacts of Freshwater on the Seasonal Variations of Surface Salinity and Circulation in the Caspian Sea

    Science.gov (United States)

    2010-01-01

    Author’s personal copy Impacts of freshwater on the seasonal variations of surface salinity and circulation in the Caspian Sea A. Birol Kara a, Alan ...circulation. Izv. Atmos. Ocean. Phys. 44, 236–249. Large, W.G., Danabasoglu, G., Doney, S.C., McWilliams , J.C., 1997. Sensitivity to surface forcing and

  5. Academic Expectations and Actual Achievements: The Roles of Hope and Effort

    Science.gov (United States)

    Levi, Uzi; Einav, Michal; Ziv, Orit; Raskind, Ilana; Margalit, Malka

    2014-01-01

    This study sought to extend the research on adolescents' hope, academic expectations, and average grades. The hope theory (Snyder, "Psychological Inquiry" 13(4):249-275, 2002), the salutogenic paradigm (with a focus on sense of coherence (SOC) (Antonovsky 1987)), and Bandura's ("Journal of Management" 38(1):9-44,…

  6. The Developmental Trajectories of Executive Function of Children and Adolescents with Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Qian, Ying; Shuai, Lan; Chan, Raymond C. K.; Qian, Qiu-Jin; Wang, Yufeng

    2013-01-01

    This study examined the developmental trajectories of executive function (EF) of children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) in Han Chinese. Five hundred and fifteen children and adolescents with ADHD and 249 healthy controls took part in this study. All of them were administered four EF tests capturing…

  7. In Situ Optimal Reshading of Arrays with Failed Elements

    Science.gov (United States)

    2016-06-13

    1982). 2. I. Barrodale and C. Philips, 11 Solution of Overdetermined Systems of linear Equations in the Chebyshev Norm, .. Algorithm 495, ACM Trans...Equations in the l~ Norm With Constraints on the Unknowns, .. Algorithm 635, ACM Trans. on Math. Software, Vol. 11, No. 3, 242-249, (1985). 5. J. T. Lewis

  8. Main: AUXRETGA2GMGH3 [PLACE

    Lifescience Database Archive (English)

    Full Text Available AUXRETGA2GMGH3 S000235 7-Sep-2000 (last modified) seki TGA-box #2 in putative auxin-resonsive element (AUX...ear extracts; Hex-like element; E1 element=-249 to -203; E2 element=-241 to -224; Called G-box by Liu et al. (1997); TGA; AUXRE; aux

  9. Analogy between Landau theory of phase transitions and Lagrangian mechanics

    OpenAIRE

    Ribeiro Filho, A.; Tilley, D.R.; Žekš, B.

    1984-01-01

    Texto completo. Acesso restrito. p. 247–249 It is shown that the definition of a stable point in landau theory is different from that used in mechanics. The implications for numerical work on phase transitions for systems that have a Lffshitz invariant are discussed.

  10. School of Advanced Military Studies Research Catalog, AY 1983 - 1984 Through AY 1993 - 1994

    Science.gov (United States)

    1994-01-01

    Every Clime and 258 098 Place: USMC Cold Weather Training Doc- trine ADA 251 427 Major Kevin Anastas , Information Overflow: Tactical Information...Major John E. Sterling. Obstacle "Theory": Do We Need It? ADA 258 249 Major Kevin Anastas , The American Way of Operational Art: Attrition or Maneuver

  11. State, Foreign Opeations, and Related Programs: FY2011 Budget and Appropriations

    Science.gov (United States)

    2010-08-19

    for global climate change, food security, and microfinance programs. The Administration also emphasized two new focus areas, adding neglected tropical...188 $249 +32% HIV/AIDS $5,609 $5,850 +4% Malaria $585 $680 +16% Maternal and Child Health $954 $983 +3% Microenterprise and Microfinance $168

  12. State, Foreign Operations, and Related Programs: FY2011 Budget and Appropriations

    Science.gov (United States)

    2011-04-22

    as did the request for global climate change, food security, and microfinance programs. The Administration also emphasized two new focus areas...188 $249 +32% HIV/AIDS $5,609 $5,850 +4% Malaria $585 $680 +16% Maternal and Child Health $954 $983 +3% Microenterprise and Microfinance $168

  13. Metabolic and hormonal responses of growing modern meat type chickens to fasting

    Science.gov (United States)

    The present study compared the effects of fasting on circulating concentrations of glucose, insulin and glucagon in male and female modern meat-type chickens (Ross 708) at three ages (19 d, 33 d and 47 d). Plasma concentrations of glucose were reduced by fasting with reductions of 24.9% (19-d-old),...

  14. 75 FR 67395 - Iron Construction Castings From Brazil, Canada, and China; Determinations

    Science.gov (United States)

    2010-11-02

    ... COMMISSION [Investigation Nos. 701-TA-249 and 731-TA-262, 263, and 265 (Third Review)] Iron Construction... countervailing duty order on heavy iron construction castings from Brazil, the antidumping duty order on heavy iron construction castings from Canada, and the antidumping duty orders on iron construction...

  15. Safety in Numbers

    Science.gov (United States)

    2010-11-27

    Bicocca. Dipartimento di Informatica , Sistemistica e Comunicazione. Laboratorio di Test e Analisi del Software, Milano. Technical Report LTA:2004:05...Communications of the ACM, 1981. 24(9): pp. 563-573. 76. Thomas Reps, On the sequential nature of interprocedural program-analysis problems. Acta Informatica

  16. Cost-Benefit Analysis of the Department of the Navy’s Transition from C-9 Aircraft to C-40 Aircraft for Logistic Support Aircraft

    Science.gov (United States)

    2009-12-01

    engine hush kits, and wiring modifications. In addition, the following upgrades are needed to bring the C- 9B’s into compliance with all FAA regulations...10. C-9B Modification Costs (FY2010 dollars) CNS/ATM $6,062,595 Engine Hush Kits $5,249,000 Interior $1,283,986 Wiring $363,392 SFAR 88

  17. Satisfacción sobre la infraestructura y la calidad de atención en la consulta de Gineco-Obstetricia de un establecimiento de atención primaria

    OpenAIRE

    Zamora Chávez, Sara Carolina

    2016-01-01

    Objetivo:Determinarelgradodesatisfaccióndelosusuariosexternosacercadelainfraestructuraylacalidaddeatención delconsultoriodelserviciodeGineco-ObstetriciadelHospitaldelaSolidaridaddeComas.MaterialyMétodos:SerealizóunestudioobservacionalnoexperimentalenelserviciodeGinecoObstetriciadelHospital delaSolidaridadComasdeLima,Perúconpacientesde18añosomásmedianteencuestaanónimasa249pacientes,conel instrumentoSERVQUALmodificado,deagosto2011afebrero2012.Teniendocomoprincipalmedidaderesultadoel detectarelgr...

  18. Judgments of Information Structure in L2 French: Nativelike Performance and the Critical Period Hypothesis

    Science.gov (United States)

    Reichle, Robert V.

    2010-01-01

    Previous studies using judgments of morphosyntactic errors have shown mixed evidence for a critical period for L2 acquisition (e.g., Birdsong & Molis, Journal of Memory and Language 44: 235-249, 2001, Johnson & Newport, Cognitive Psychology 21: 60-99, 1989). This study uses anomalies in the domain of information structure, the interface…

  19. 17 CFR 240.10b-18 - Purchases of certain equity securities by the issuer and others.

    Science.gov (United States)

    2010-04-01

    ... report their repurchasing activity as required by Item 8 of Form N-CSR (17 CFR 249.331; 17 CFR 274.128). (a) Definitions. Unless otherwise provided, all terms used in this section shall have the same meaning as in the Act. In addition, the following definitions shall apply: (1) ADTV means the...

  20. Movements and site fidelity of harbour seals (Phoca vitulina) in Kattegat, Denmark, with implications for the epidemiology of the phocine distemper virus

    DEFF Research Database (Denmark)

    Dietz, R.; Teilmann, J.; Andersen, S.M.;

    2013-01-01

    Kattegat with a maximum distance of 249 km from the tagging haul-out site. Overall, females travelled over a wider area compared with males [90% kernel home range (KHR) females, 5189 km2; males, 3293 km2). KHR calculated for yearlings (6414 km2) is larger than for subadults (2534 km2), which again...

  1. 75 FR 53744 - Service-Connected and Other Disability Compensation

    Science.gov (United States)

    2010-09-01

    ... cardiovascular disease secondary to service-connected lower extremity amputation. 5.249 Special service..., ``Benefits for persons disabled by treatment or vocational rehabilitation''. Thus, ``disability compensation... nature. For example, VA would never require a veteran who had suffered an amputation of a limb...

  2. Cyberbullying Behaviors among Female College Students: Witnessing, Perpetration, and Victimization

    Science.gov (United States)

    Selkie, Ellen M.; Kota, Rajitha; Moreno, Megan

    2016-01-01

    Problem: Cyberbullying is common among adolescents, and emerging studies also describe this phenomenon in college students. Less is known about specific cyberbullying behaviors and roles in cyberbullying incidents experienced by college females. Methods: 249 female students from 4 colleges completed online surveys assessing involvement in 11…

  3. Beiträge zur Kenntnis der Pupillacea VII. Über zwei Wenig Bekannte Valloniidae

    NARCIS (Netherlands)

    Gittenberger, E.

    1977-01-01

    Spermodea spermatia (Da Silva e Castro) (Fig. 2) Helix spermatia J. da Silva e Castro, 1887: 249 (Locus typicus: "au bois de Bussaco", Bugaco, 40°22'N 8°21'W, etwa 15 km nnö. von Coimbra, Beira Litoral, Portugal — ? Syntypus: MHNG-Bgt2)). — A. Locard, 1899: 61. Helix (Acanthinula) spermatia — C. A.

  4. Gclust Server: 91921 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 91921 Bsu_BSU36510=nrgA Cluster Sequences Related Sequences(249) 404 ammonium trans...porter 1 1.00e-60 0.0 0.0 0.0 0.0 3.23 0.0 Show 91921 Cluster ID 91921 Sequence ID Bsu_BSU36510=nrgA Link to

  5. Gclust Server: 192198 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 192198 DME_CG30182_28573654 Cluster Sequences - 249 CG30182: CG30182-PA 1 1.00e-99 ...0.0 0.0 0.0 0.0 0.0 12.5 Show 192198 Cluster ID 192198 Sequence ID DME_CG30182_28573654 Link to cluster sequ

  6. Locomotor diseases among male long-haul truck drivers and other professional drivers

    DEFF Research Database (Denmark)

    Jensen, Anker; Kaerlev, Linda; Tüchsen, Finn

    2007-01-01

    -249) and for other truck drivers (SHR: 130, 95% CI: 108-156) compared to bus drivers (SHR: 110, 95% CI: 79-149). All drivers had high SHR for lesions of the ulnar nerve (SHR: 159, 95% CI: 119-207), especially bus drivers (SHR: 197, 95% CI: 116-311). Long-haul truck drivers had high SHRs for synovitis and bursitis...

  7. Financial Information Source, Knowledge, and Practices of College Students from Diverse Backgrounds

    Science.gov (United States)

    Mimura, Yoko; Koonce, Joan; Plunkett, Scott W.; Pleskus, Lindsey

    2015-01-01

    Using cross-sectional data, we examined the financial information sources, financial knowledge, and financial practices of young adults, many of whom are first generation college students, ethnic minorities, and immigrants or children of immigrants. Participants (n = 1,249) were undergraduate students at a large regional comprehensive university.…

  8. University Marine Biological Station Millport Annual Report

    Science.gov (United States)

    1987-07-31

    34Species of the Family Nuculidae (Bivalvia: Protobranchia) from the Deep Atlantic: their Taxonomy , Form and Function". (Supervisor: Professor J.A. Allen...ALLEN, J.A., & HANNAH, F.J. 1986, A reclassification of the Subclass Protobrancnia ( Mollusca : Bivalvia). J ConCn. 32j 225-249. ALLEN, J.A. 1987. Sir

  9. Volumetric Collection Efficiency and Droplet Sizing Accuracy of Rotary Impactors

    Science.gov (United States)

    2011-02-01

    slide. The DropVision software returns results in the form of DV50, DV10, and DV90 as well as, the cu ‐ mulative droplet size distribution and coverage...field samplers for monitoring spray drift. Crop Prot. 15(3): 249‐257. Fox, R. D., R. C. Derksen, H. Zhu, R. A. Downer, and R. D. Brazee . 2004. Airborne

  10. "I Like to Plan Events": A Document Analysis of Essays Written by Applicants to a Public Relations Program

    Science.gov (United States)

    Taylor, Ronald E.

    2016-01-01

    A document analysis of 249 essays written during a 5-year period by applicants to a public relations program at a major state university in the southeast suggests that there are enduring reasons why students choose to major in public relations. Public relations is described as a major that allows for and encourages creative expression and that…

  11. 78 FR 75395 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Order Granting...

    Science.gov (United States)

    2013-12-11

    ... rules are silent on when series may be added. Therefore, the Exchange is proposing to add language... Exchange also proposed to add language stating that the proposed provisions in Rules 5.5(d)(4) and 24.9(a... From the Federal Register Online via the Government Publishing Office SECURITIES AND...

  12. ABA and Diverse Cultural and Linguistic Environments: A Welsh Perspective

    Science.gov (United States)

    Jones, E. W.; Hoerger, M.; Hughes, J. C.; Williams, B. M.; Jones, B.; Moseley, Y.; Hughes, D. R.; Prys, D.

    2011-01-01

    Gwynedd Local Education Authority (LEA) in North West Wales, UK, is funding a small-scale autism-specific specialist education service using ABA methodology. The program is available through the medium of Welsh, English or bilingually, depending on the individual needs of the child (Jones and Hoerger in Eur J Behav Anal 10:249-253,…

  13. The Impact of Spirituality on Cardiovascular Reactivity Among African Americans

    Science.gov (United States)

    2010-03-16

    1999). The item related to values found in the BMMRS originated from the Intrinsic/Extrinsic Revised Scale ( Gorsuch & McPherson, 1989) which is...role of cortisol and dehydroepiandrosterone in human development and psychopathology. British Journal of Psychiatry, 179, 243-249. Gorsuch , R

  14. The Family Backpack Project: Responding to Dual-Language Texts through Family Journals

    Science.gov (United States)

    Rowe, Deborah; Fain, Jeanne Gilliam

    2013-01-01

    The Family Backpack Project provided 249 low-income, prekindergarten children and their families with opportunities to read and listen to audio recordings of 3 sets of books in their homes. Families received English or dual-language texts (English plus Spanish, Arabic, Kurdish, or Somali) matched to their home languages. Children and their…

  15. Learning Technology Specification: Principles for Army Training Designers and Developers

    Science.gov (United States)

    2013-09-01

    training: capitalizing on lessons learned. International Journal of Training and Development 14, 239-249. Bloom , B. S . (1984). Taxonomy of... educational objectives . Boston: Allyn and Bacon. Bower, M. (2008). Affordance analysis- matching learning tasks with learning technologies... Educational Media International, 45, 3-15. Bransford, J. D., Sherwood, R. D., Hasselbring, T. S ., Kinzer, C. K., and Williams, S . M. (1990). Anchored

  16. Mechanisms of alpha-Synuclein Aggregation and Toxicity

    Science.gov (United States)

    2006-09-01

    K. R., Krajcarski, D. T., and Rayner, D. M. (1978) FEBS Lett. 94, 249–252 31. Thomson, A. M., Rogers , J. T., and Leedman, P. J. (1999) Int. J...McNaught, K.S., and Jenner, P. (2001). Proteasomal function is im- Chartier -Harlin, M. (2000). Linkage exclusion in French families with paired in

  17. Preliminary Evaluation Study on the Participation Level of China in ISO TCM International Standardization Actives%我国参与ISO中医药国际标准化水平评价初探

    Institute of Scientific and Technical Information of China (English)

    包文虎; 王璐; 李静; 顾晓静; 陶有青; 徐春波; 李振吉

    2015-01-01

    2009年成立的ISO/TC249中医药技术委员会为中医药国际标准化发展打开了又一扇大门。为了解ISO/TC249发展现状和问题,为决策提供依据,本文初步尝试从参与TC管理水平、注册专家水平、实质性参与标准制定水平和ISO成员国参与水平4个方面探索建立指标体系,并对我国参与ISO中医药国际标准化的水平进行了初步评价。通过评价认为,我国参与ISO/TC249管理水平较好;在注册专家绝对数量上优势较大,但专家在WG的分布和专家结构有待优化;在实质性参与标准制定方面的优势相比TC管理和注册专家数量的优势基础还有待提高;在ISO成员国参与水平上还有提升空间。%The establishment of ISO/TC249 in 2009 have opened a new door for TCM international standardization .To learn about the current situation , locate problems of the development ISO/TC249 and support the decision-making, this paper tries to set up an evaluation index system for participation level of China in ISO TCM international standardization actives .The system includes four aspects:the participation level of TCM management , the level of experts ’ registration, participation level of standards developing and the participation level of ISO member bodies in ISO /TC249.The results show that:1) China had greatly engaged in the man-agement of TCM;2) It had a quantity advantage in registered experts , but still needs enlarge experts ’ distribution and optimize expert’s structure in WG;3) In terms of standards developing , China’s advantage was not as significant as participation level of management and the quality of experts;4) Further contribution should be made to the level of ISO member bodies participated in ISO/TC249 .

  18. Factors affecting willingness to accept circumcision in male medical students%医学生包皮环切术接受意愿影响因素分析

    Institute of Scientific and Technical Information of China (English)

    王蕾; 牟李红; 李革; 梁浩; 宋银吟

    2012-01-01

    Objective To examine cognitive status of circumcision and related factors for providing basis for developing materials of promoting willingness to accept circumcision in key population of AIDS prevention. Methods Cluster random sampling method was used to select 581 students of grade 1 -4 from a medical university and a cross-sectional survey was conducted with a self-administrated questionnaire. Results The male students had certain understanding of the hazards of too long foreskin or phimosis and the common causes of surgery, and die full awareness rates of all hazards and common causes of surgery were 39. 65% (224/565) and 7. 69% (35/455). Only 38. 9% (177/455) of the students realized the operation could prevent human immunodeficiency virus infection and other sexually transmitted diseases. The reasons for the students not to choose the surgery were no health risk caused by phimosis (76. 31% ,190/249) , worrying about the risk of surgery (38. 96% , 97/249) , without knowledge about medical benefits of the surgery ( 26. 51% , 66/249) .worrying about the influence of the surgery on sexual function(22. 89% ,57/249) ,and worrying about high cost of the surgery( 15. 667c ,39/249). The acceptance rate of the surgery was increased to 33.06% (81/253) after knowing very low surgical complication rate and the preventive effects for AIDS and other sexually transmitted diseases among the students. Conclusion Popularizing related knowledge and making the surgery more safe and less cost may increase the willingness to accept circumcision among male medical students.%目的 了解重庆医科大学男性医学生对包皮环切术的认知状况及影响因素,为进一步提高艾滋病重点人群包皮环切术接受意愿宣传提供科学依据.方法 采用自制问卷对整群随机抽样法抽取的580名1~4年级大学生进行横断面调查.结果 男生对包皮过长或包茎的危害、手术常见原因有一定了解,但完全知晓率分别为39.65%(224

  19. Epidemiology of Complex Congenital Heart Disease in Defective Stillbirth Fetus%复杂性先天性心脏病在非活产缺陷儿中的发生状况

    Institute of Scientific and Technical Information of China (English)

    欧艳秋; 刘小清; 麦劲壮; 韩凤珍; 陈寄梅; 潘微; 庄建

    2012-01-01

    Objective:To investigate the prevalence and diagnosis of complex congenital heart disease( CCHD )in defective stillbirth fetus. Methods : We retrospectively studied 14342 fetuses and new born babies in our hospital from 2005 to 2010,that including 249 cases of defective stillbirth. All diagnosis was confirmed by fetal echocardiography. The defective rate and the component ratio of CCHD in stillbirth fetuses were analyzed. Results:The total detective rate of CHD in all birth was 10. 95‰( 157/14342 ),the detective rate in defective stillbirth was 1. 74%( 249/14342 )and CCHD in defective stillbirth was 17. 27%( 43/249 ). The CCHD occurrence as complete atrioventricular septal defect in 52‰( 13/249 ) cases,double outlet of right ventricle in 36‰ cases( 9/249 ), single ventricle in 32‰ cases( 8/ 249 ) and great artery conversion in 24‰ cases( 6/249 ). 95. 35% parents of CCHD fetuses chose to terminate the pregnancy. The detective rate for CCHD was higher in female fetuses than that in male( 30. 38% vs. 14. 55% ,P = 0. 0086 ). The average diagnosis time for CCHD fetuses was( 26. 9±4. 9 )weeks of gestation,and 67. 44% of diagnosis was made between 20 ~ 30 weeks of gestation. Conclusion:There was a high detective rate for CCHD in defective stillbirth. Fetal echocardiography was an effective and helpful method for CCHD diagnosis in fetuses.%目的:了解复杂性先天性心脏病(CCHD)在非活产缺陷儿中的检出和诊断情况.方法:通过病历回顾的方法选取我院2005-01-01 至2010-12-31胎儿及新生儿14 342例,非活产缺陷儿249例.主要诊断手段为胎儿超声心动图.分析CCHD在非活产缺陷儿中的检出率及构成比例.结果:14 342例胎儿及新生儿的先天性心脏病总检出率为10.95‰(157例),非活产缺陷儿的249例(1.74%),CCHD 43例占非活产缺陷儿的17.27%.43例中CCHD的亚型比例分布依次是完全性房室间隔缺损52‰(13例);右心室双出口36‰(9例)、单心室32‰(8

  20. Correlation between body mass index and overactive bladder symptoms in pre-menopausal women

    Directory of Open Access Journals (Sweden)

    Thais Palma

    2014-01-01

    Full Text Available Objective: The aim of the study was to establish a correlation between Overactive Bladder (OAB symptoms and Body Mass Index (BMI in women aged 20-45. Methods: We interviewed 1.050 women aged 20-45 in the area of Campinas, Brazil, to investigate the prevalence of overactive bladder symptoms. In this study, we used the ICIQ-OAB questionnaire (ICS standard, in its validated portuguese version and a specific questionnaire for the demographics, which includes information about BMI. Results: Overall, women with BMI ≥30 presented a significantly higher score than women with a lower BMI (18.5 - 24.9 (p=0.0066. In the analysis of individual symptoms, no significant differences were found regarding urinary frequency (p=0.5469. Women with BMI ≥30 presented more nocturia than women with BMI ranging between 18.5 and 24.9 (p=0.0154. Women in the group of BMI 25 - 29.9 presented more urgency than women with BMI 18.5 - 24.9 (p=0.0278. Significant difference was also found regarding urge-incontinence; women with BMI 25 - 29.9 presented a higher score than women in the group 18.5 - 24.9 (p= 0.0017. Analysis was also performed on the visual analogue scale regarding how much each symptom bothers the women (quality of life. There were no significant differences regarding frequency, nocturia or urgency but urgency incontinence bother was significant. Women with BMI 25 - 29.9 were more bothered by incontinence than women with BMI 18.5 - 24.9 (p=0.002. Conclusion: In conclusion, this study reinforces the correlation between BMI and OAB symptoms. Obese women present more OAB symptoms than non-obese women.

  1. Single amino acid mutation alters thermostability of the alkaline protease from Bacillus pumilus: thermodynamics and temperature dependence.

    Science.gov (United States)

    Huang, Rong; Yang, Qingjun; Feng, Hong

    2015-02-01

    Dehairing alkaline protease (DHAP) from Bacillus pumilus BA06 has been demonstrated to have high catalytic efficiency and good thermostability, with potential application in leather processing. In order to get insights into its catalytic mechanism, two mutants with single amino acid substitution according to the homology modeling and multiple sequence alignment were characterized in thermodynamics of thermal denaturation and temperature dependence of substrate hydrolysis. The results showed that both mutants of V149I and R249E have a systematic increase in catalytic efficiency (kcat/Km) in a wide range of temperatures, mainly due to an increase of k1 (substrate diffusion) and k2 (acylation) for V149I and of k2 and k3 (deacylation) for R249E. In comparison with the wild-type DHAP, the thermostability is increased for V149I and decreased for R249E. Thermodynamic analysis indicated that the free energy (ΔGa°) of activation for thermal denaturation may govern the thermostability. The value of ΔGa° is increased for V149I and decreased for R249E. Based on these data and the structural modeling, it is suggested that substitution of Val149 with Ile may disturb the local flexibility in the substrate-binding pocket, leading to enhancement of binding affinity for the substrate. In contrast, substitution of Arg249 with Glu leads to interruption of interaction with the C-terminal of enzyme, thus resulting in less thermostability. This study indicates that amino acid residues in the active center or in the substrate-binding pocket may disturb the catalytic process and can be selected as the target for protein engineering in the bacterial alkaline proteases.

  2. Identification of a disulfide bridge important for transport function of SNAT4 neutral amino acid transporter.

    Directory of Open Access Journals (Sweden)

    Rugmani Padmanabhan Iyer

    Full Text Available SNAT4 is a member of system N/A amino acid transport family that primarily expresses in liver and muscles and mediates the transport of L-alanine. However, little is known about the structure and function of the SNAT family of transporters. In this study, we showed a dose-dependent inhibition in transporter activity of SNAT4 with the treatment of reducing agents, dithiothreitol (DTT and Tris(2-carboxyethylphosphine (TCEP, indicating the possible involvement of disulfide bridge(s. Mutation of residue Cys-232, and the two highly conserved residues Cys-249 and Cys-321, compromised the transport function of SNAT4. However, this reduction was not caused by the decrease of SNAT4 on the cell surface since the cysteine-null mutant generated by replacing all five cysteines with alanine was equally capable of being expressed on the cell surface as wild-type SNAT4. Interestingly, by retaining two cysteine residues, 249 and 321, a significant level of L-alanine uptake was restored, indicating the possible formation of disulfide bond between these two conserved residues. Biotinylation crosslinking of free thiol groups with MTSEA-biotin provided direct evidence for the existence of a disulfide bridge between Cys-249 and Cys-321. Moreover, in the presence of DTT or TCEP, transport activity of the mutant retaining Cys-249 and Cys-321 was reduced in a dose-dependent manner and this reduction is gradually recovered with increased concentration of H2O2. Disruption of the disulfide bridge also decreased the transport of L-arginine, but to a lesser degree than that of L-alanine. Together, these results suggest that cysteine residues 249 and 321 form a disulfide bridge, which plays an important role in substrate transport but has no effect on trafficking of SNAT4 to the cell surface.

  3. Radiochemical studies of neutron deficient actinide isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Williams, K.E.

    1978-04-01

    The production of neutron deficient actinide isotopes in heavy ion reactions was studied using alpha, gamma, x-ray, and spontaneous fission detection systems. A new isotope of berkelium, /sup 242/Bk, was produced with a cross-section of approximately 10 ..mu..b in reactions of boron on uranium and nitrogen on thorium. It decays by electron capture with a half-life of 7.0 +- 1.3 minutes. The alpha-branching ratio for this isotope is less than 1% and the spontaneous fission ratio is less than 0.03%. Studies of (Heavy Ion, pxn) and (Heavy Ion, ..cap alpha..xn) transfer reactions in comparison with (Heavy ion, xn) compound nucleus reactions revealed transfer reaction cross-sections equal to or greater than the compound nucleus yields. The data show that in some cases the yield of an isotope produced via a (H.I.,pxn) or (H.I.,..cap alpha..xn) reaction may be higher than its production via an xn compound nucleus reaction. These results have dire consequences for proponents of the ''Z/sub 1/ + Z/sub 2/ = Z/sub 1+2/'' philosophy. It is no longer acceptable to assume that (H.I.,pxn) and (H.I.,..cap alpha..xn) product yields are of no consequence when studying compound nucleus reactions. No evidence for spontaneous fission decay of /sup 228/Pu, /sup 230/Pu, /sup 232/Cm, or /sup 238/Cf was observed indicating that strictly empirical extrapolations of spontaneous fission half-life data is inadequate for predictions of half-lives for unknown neutron deficient actinide isotopes.

  4. Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter

    Energy Technology Data Exchange (ETDEWEB)

    Gobrecht, J.; Gaeggeler, H.; Herlach, D.; Junker, K.; Kettle, P.-R.; Kubik, P.; Zehnder, A. [eds.

    2000-07-01

    lthough originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element {sup 107} Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.

  5. Transuranium Processing Plant semiannual report of production, status, and plans for period ending December 31, 1975

    Energy Technology Data Exchange (ETDEWEB)

    King, L.J.; Bigelow, J.E.; Collins, E.D.

    1976-10-01

    Between July 1, 1975, and December 31, 1975, maintenance was conducted at TRU for a period of three months, 295 g of curium oxide (enough for approximately 26 HFIR targets) were prepared, 100 mg of high-purity /sup 248/Cm, were separated from /sup 252/Cf that had been purified during earlier periods, 11 HFIR targets were fabricated, and 28 product shipments were made. No changes were made in the chemical processing flowsheets normally used at TRU during this report period. However, three equipment racks were replaced (with two new racks) during this time. In Cubicle 6, the equipment replaced was that used to decontaminate the transplutonium elements from rare earth fission products and to separate curium from the heavier elements by means of the LiCl-based anion-exchange process. In Cubicle 5, the equipment used to separate the transcurium elements by high-pressure ion exchange and to purify berkelium by batch solvent extraction was replaced. Two neutron sources were fabricated, bringing the total fabricated to 79. One source that had been used in a completed project was returned to the TRU inventory and is available for reissue. Three sources, for which no further use was foreseen, were processed to isolate and recover the ingrown /sup 248/Cm and the residual /sup 252/Cf. Eight pellets, each containing 100 ..mu..g of high-purity /sup 248/Cm were prepared for irradiation in HFIR to study the production of /sup 250/Cm. The values currently being used for transuranium element decay data and for cross-section data in planning irradiation-processing cycles, calculating production forecasts, and assaying products are tabulated.

  6. Clinic application of serum low-density lipoprotein cholesterol level in predicting expansion hematoma in elderly male patients with acute hypertensive intracerebral hemorrhage%血清LDL-C水平对老年男性高血压性脑出血血肿扩大的预测作用

    Institute of Scientific and Technical Information of China (English)

    周红霞; 刘首峰; 李玉旺; 王欣; 徐小林

    2015-01-01

    Objective To investigate whether serum level of low-density lipoprotein cholesterol can predict the expan⁃sion of hemorrhage growth in elderly male patients with acute hypertensive intracerebral hemorrhage. Methods Patients (n=108) who visited our hospital with from June 2012 until May 2014 spontaneous hypertensive intracerebral hemorrhage with⁃in 6 hours of onset which is confirmed by initial computed tomography (CT) were sent to repeated CT within 24 hours of on⁃set. All selected patients were divided into the LDL-C≥2.49 mmol/L group and LDL-C<2.49 mmol/L group. Clinical data of these 2 groups were compared and the relationships of hematoma growth and its risk factors were analyzed. Results Baseline blood pressure, the level of blood glucose, PT, APTT, FIB, PLT and hemorrhage volume did not differ significantly between the LDL-C≥2.49 mmol/L group and LDL-C<2.49 mmol/L group. The ratio of hemorrhage growth in LDL-C<2.49 mmol/L group was significantly higher than that in LDL-C≥2.49 mmol/L group (34.21%vs 11.43%). Multiple logistic regres⁃sion analysis showed that LDL-C<2.49 mmol/L was the only risk factor contribute to hemorrhage growth. Conclusion Pa⁃tients with LDL-C<2.49 mmol/L in acute intracerebral hemorrhage are of high risk of hemorrhage growth so early attention and appropriate procedure are needed to prevent or slow its growth.%目的:探讨血清低密度脂蛋白胆固醇(LDL-C)水平对老年男性高血压性脑出血急性期血肿扩大有无预测作用。方法收集我院2012年6月—2014年5月发病6 h以内的老年男性高血压性脑出血患者108例,按发病时LDL-C水平分为LDL-C<2.49 mmol/L组和LDL-C≥2.49 mmol/L组,对2组患者入院时的收缩压(SBP)、舒张压(DBP)、血糖水平、凝血酶原时间(PT)、部分活化凝血酶时间(APTT)、纤维蛋白原(FIB)、血小板计数、血肿体积进行对比分析,并于发病24 h复查头CT了解2组血肿扩大情况并进

  7. Evaluation of anticonvulsant actions of dibromophenyl enaminones using in vitro and in vivo seizure models.

    Directory of Open Access Journals (Sweden)

    Mohamed G Qaddoumi

    Full Text Available Epilepsy and other seizure disorders are not adequately managed with currently available drugs. We recently synthesized a series of dibromophenyl enaminones and demonstrated that AK6 and E249 were equipotent to previous analogs but more efficacious in suppressing neuronal excitation. Here we examined the actions of these lead compounds on in vitro and in vivo seizure models. In vitro seizures were induced in the hippocampal slice chemically (zero Mg2+ buffer and picrotoxin and electrically using patterned high frequency stimulation (HFS of afferents. In vivo seizures were induced in rats using the 6 Hz and the maximal electroshock models. AK6 (10 µM and E249 (10 µM depressed the amplitude of population spikes recorded in area CA1 of the hippocampus by -50.5±4.3% and -40.1±3.1% respectively, with partial recovery after washout. In the zero Mg2+ model, AK6 (10 µM depressed multiple population spiking (mPS by -59.3±6.9% and spontaneous bursts (SBs by -65.9±7.2% and in the picrotoxin-model by -43.3±7.2% and -50.0±8.3%, respectively. Likewise, E249 (10 µM depressed the zero-Mg2+-induced mPS by -48.8±9.5% and SBs by -55.8±15.5%, and in the picrotoxin model by -37.1±5.5% and -56.5±11.4%, respectively. They both suppressed post-HFS induced afterdischarges and SBs. AK6 and E249 dose-dependently protected rats in maximal electroshock and 6 Hz models of in vivo seizures after 30 min pretreatment. Their level of protection in both models was similar to that obtained with phenytoin Finally, while AK6 had no effect on locomotion in rats, phenytoin significantly decreased locomotion. AK6 and E249, suppressed in vitro and in vivo seizures to a similar extent. Their in vivo activities are comparable with but not superior to phenytoin. The most efficacious, AK6 produced no locomotor suppression while phenytoin did. Thus, AK6 and E249 may be excellent candidates for further investigation as potential agents for the treatment of epilepsy syndromes

  8. Analysis of Three Cobble Ring Sites at Abiquiu Reservoir, Rio Arriba County, New Mexico.

    Science.gov (United States)

    1989-01-01

    were made at 2000X with a Watson image-splitting measurement instrument. Seven independent measurements were made and a mean value and standard...152 88 0 debitage 12 cripto -c 11 4 1 5 ’ . 2 1 S G 148 E6 (t devitage ,1C" obm-idian 1 1I 21 S 6 15’ -11 6 ae~itaoe Ilvqrtzite 4,1 1 5 1 k1 !I t 21 S 6...17 N1 T3 11I? 24Q 30 debitaqe 9 Crypto-C 11 17 M T7 113 249 () debitage 12 cripto -c .6 4 17 Mi T3 113 2149 370 debitaqe I1I crvpto-c ~ 17? N TT3 11 249

  9. Partial trisomy 4q and partial monosomy 9p in a girl with choanal atresia and various dysmorphic findings.

    Science.gov (United States)

    Cakmak-Genc, Gunes; Karakas-Celik, Sevim; Dursun, Ahmet; Piskin, İbrahim Etem

    2015-09-01

    We report a new-born girl with partial trisomy of 4q28-qter and partial monosomy of 9p24-9ter. Our patient has choanal atresia, hypertelorism, wide nasal bridge, high arched palate, discrete nipples, heart defects, myoclonic seizures and various dysmorphic findings. Standard chromosomal analysis with G-banding with Trypsin-Giemsa revealed 46,XX,der(9)t(4;9)(q28;p24) resulting from the mother's t(4,9) (q28;p24) karyotype. Deletions of the terminal part of 9p and partial trisomy of chromosome 4q are rare chromosomal alterations. To our knowledge, this is the first report of choanal atresia in a patient with a partial trisomy of 4q28-qter and partial monosomy 9p24-9ter combination, which were detected by integrated cytogenetic and genomic analysis.

  10. Recent progress in 8igenomic research of liver cancer

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Along the course of occurrence and development of liver cancer,the corresponding somatic cells accumulate some important genetic variations.These variations may be divided into two categories.For the genetic changes closely related to etiology of liver cancer,the well-known cases include insertion and integration of the hepatitis B virus(HBV) DNA after infection,and mutations at site 249 of the tumor suppressor gene p53 induced by exposure to aflatoxin B1.The secondary genetic changes include amplification and deletion of certain chromosome regions,mutations in p53 at the sites other than 249,as well as the mutational activation of the Wnt/β-catenin signal pathway.The tumor cells with these genetic variations may gradually become the dominant clones under evolutionary selection.Besides,identification of genetic susceptible against risk of liver malignancy is also an important aspect of research in this field.

  11. Recent progress in 8igenomic research of liver cancer

    Institute of Scientific and Technical Information of China (English)

    HAN ZeGuang

    2009-01-01

    Along the course of occurrence and development of liver cancer, the corresponding somatic cells ac-cumulate some important genetic variations. These variations may be divided into two categories. For the genetic changes closely related to etiology of liver cancer, the well-known cases include insertion and integration of the hepatitis B virus (HBV) DNA after infection, and mutations at site 249 of the tumor suppressor gene p53 induced by exposure to aflatoxin B1. The secondary genetic changes include amplification and deletion of certain chromosome regions, mutations in p53 at the sites other than 249, as well as the mutational activation of the Wnt/β-catenin signal pathway. The tumor cells with these genetic variations may gradually become the dominant clones under evolutionary selection. Besides, identification of genetic susceptible against risk of liver malignancy is also an important aspect of re-search in this field.

  12. Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-d-glyceric acid.

    Science.gov (United States)

    Ladame, Sylvain; Castilho, Marcelo S; Silva, Carlos H T P; Denier, Colette; Hannaert, Véronique; Périé, Jacques; Oliva, Glaucius; Willson, Michèle

    2003-11-01

    We report here the first crystal structure of a stable isosteric analogue of 1,3-bisphospho-d-glyceric acid (1,3-BPGA) bound to the catalytic domain of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase (gGAPDH) in which the two phosphoryl moieties interact with Arg249. This complex possibly illustrates a step of the catalytic process by which Arg249 may induce compression of the product formed, allowing its expulsion from the active site. Structural modifications were introduced into this isosteric analogue and the respective inhibitory effects of the resulting diphosphorylated compounds on T. cruzi and Trypanosoma brucei gGAPDHs were investigated by enzymatic inhibition studies, fluorescence spectroscopy, site-directed mutagenesis, and molecular modelling. Despite the high homology between the two trypanomastid gGAPDHs (> 95%), we have identified specific interactions that could be used to design selective irreversible inhibitors against T. cruzi gGAPDH.

  13. An integrated catalog of reference genes in the human gut microbiome

    DEFF Research Database (Denmark)

    Li, Junhua; Jia, Huijue; Cai, Xianghang

    2014-01-01

    Many analyses of the human gut microbiome depend on a catalog of reference genes. Existing catalogs for the human gut microbiome are based on samples from single cohorts or on reference genomes or protein sequences, which limits coverage of global microbiome diversity. Here we combined 249 newly ...... signatures. This expanded catalog should facilitate quantitative characterization of metagenomic, metatranscriptomic and metaproteomic data from the gut microbiome to understand its variation across populations in human health and disease.......Many analyses of the human gut microbiome depend on a catalog of reference genes. Existing catalogs for the human gut microbiome are based on samples from single cohorts or on reference genomes or protein sequences, which limits coverage of global microbiome diversity. Here we combined 249 newly...

  14. Disperse Red 1 (textile dye) induces cytotoxic and genotoxic effects in mouse germ cells.

    Science.gov (United States)

    Fernandes, Fábio Henrique; Bustos-Obregon, Eduardo; Salvadori, Daisy Maria Fávero

    2015-06-01

    Disperse Red 1 (DR1), which is widely used in the textile industry, is an azo dye that contributes to the toxicity and pollution of wastewater. To assess the toxic effects of DR1 on reproduction, sexually mature male mice (Mus musculus, strain CF-1) were orally (gavage) treated with single doses of the compound at 20, 100 and 500 mg/kg body weight. Testicular features and sperm parameters were evaluated 8.3, 16.6 and 24.9 days after treatments. In addition to testicular toxicity caused by the dye, the data clearly showed an increased frequency of sperm with abnormal morphology and decreased fertility. An increased amount of DNA damage was also detected in testis cells 16.6 and 24.9 days after treatments with 100 and 500 mg/kg. This study demonstrated the toxic and genotoxic effects of DR1, indicating the harmful activity of this dye on reproductive health.

  15. 血清低密度脂蛋白与急性出血性卒中患者病情的相关性分析%Analysis of relation between serum low density lipoprotein cholesterol and the pathogenetic condition of pa-tients with acute hemorrhagic stroke

    Institute of Scientific and Technical Information of China (English)

    邬莹

    2015-01-01

    Objective To investigate the relation between serum low density lipoprotein cholesterol(LDL‐C)and the patho‐genetic condition of patients with acute hemorrhagic stroke. Methods The clinical data of 100 cases of patients with acute hem‐orrhagic stroke in our hospital from January 2010 to January 2013 were analyzed retrospectively. All the patients were divided into 43 cases of LDL‐C0.05).The incidence of hematoma enlargement of LDL‐C<2.49 mmol/L group was significantly increased, compared with LDL‐C≥2.49 mmol/L group, the difference was statistically significant(P<0.05), and the level of LDL‐C in patients with hematoma enlargement was significantly lower than that of patients without hematoma enlargement, the difference was statistically signifi‐cant(P<0.05). Conclusion The pathogenetic condition of patients with acute hemorrhagic stroke is related with the serum LDL‐C level, patients with LDL‐C<2.49 mmol/L are prone to occur hematoma enlargement. It should pay much attention to the detection of serum LDL‐C on admission, w hich is helpful to predict the pathogenetic condition.%目的探讨血清低密度脂蛋白(LDL‐C)和急性出血性卒中患者病情的关系。方法100例急性出血性卒中患者按照入院时LDL‐C水平分成LDL‐C<2.49 mmol/L组43例与LDL‐C≥2.49 mmol/L组57例,分析急性出血性卒中患者病情程度与LDL‐C水平的相关性。结果2组患者在凝血酶原时间、收缩压、舒张压、血肿大小、纤维蛋白原、部分活化凝血酶时间、血小板数量以及血糖等生化指标水平比较差异无统计学意义(P>0.05);LDL‐C<2.49 mmol/L组血肿扩大发生率显著上升,与LDL‐C≥2.49 mmol/L组相比,差异有统计学意义(P<0.05),且血肿扩大患者的LDL‐C水平显著低于无血肿扩大患者,差异有统计学意义(P<0.05)。结论急性出血性卒中患者病情与血清LDL‐C水平有关,LDL‐C<2.49 mmol

  16. Spectrophotometric determination of tranexamic acid using vanillin

    Institute of Scientific and Technical Information of China (English)

    EM.A.Rind; M.G.H.Laghari; A.H.Memon; U.R.Mughal; F. Almani; N.Me-mon; M.Y.Khuhawar; M.L.Maheshwari

    2009-01-01

    A new spectrophotometric method has been examined for the determination of the tranexamic acid (TA)by derivatization with vanillin(VAN).The molar absorptivity of TA was calculated 25 160 L·mol-1·cm-1at λ max 354 nm and obeyed the Beer's law within 0.5-2.5 μg·mL-1.The color reaction was highly stable and didnot show any change in absorbance up to 24 h.The method was applied for the analysis of TA from capsules,injections and tooth pastes.The amounts of TA found in capsules,injections and tooth pastes of various pharmaceutical companies were observed with 249.0-250.9 mg/capsule,249.3-250.7 mg/injection and 0.048%-0.049%in tooth pastes with relative standard deviation(RSD)0.2%-5.0%(n=3).

  17. Genetic predisposition of variants in TLR2 and its co-receptors to severe malaria in Odisha, India.

    Science.gov (United States)

    Panigrahi, Subhendu; Kar, Avishek; Tripathy, Sagnika; Mohapatra, Manoj K; Dhangadamajhi, Gunanidhi

    2016-02-01

    Although the role of TLRs signalling in malaria pathogenesis is well established, contribution of individual TLR to clinical outcome of malaria still remains inconclusive. Given the importance of TLR2 and its co-receptors in recognising distinct structural forms of key malaria toxins and mediating innate immune response, it is essential to delineate their genetic contribution. Variants in TLR1 (I602S) and TLR6 (P249S) were genotyped by PCR-RFLP methods, and TLR2 (I/D) was genotyped by PCR in 200 samples each from uncomplicated malaria (UM) and severe malaria (SM). Further, SM was categorised into its sub-clinical groups (CM and NCSM or SOD and MODS) and analysed. The results showed the PP genotype of TLR6 (P249S) to be significantly more common in UM (P malaria.

  18. Birth weight and systolic blood pressure in adolescence and adulthood

    DEFF Research Database (Denmark)

    Gamborg, Michael; Byberg, Liisa; Rasmussen, Finn

    2007-01-01

    The authors investigated the shape, sex- and age-dependency, and possible confounding of the association between birth weight and systolic blood pressure (SBP) in 197,954 adults from 20 Nordic cohorts (birth years 1910-1987), one of which included 166,249 Swedish male conscripts. Random-effects m......The authors investigated the shape, sex- and age-dependency, and possible confounding of the association between birth weight and systolic blood pressure (SBP) in 197,954 adults from 20 Nordic cohorts (birth years 1910-1987), one of which included 166,249 Swedish male conscripts. Random...... with a birth weight greater than 4 kg, SBP increased with birth weight (p groups (p

  19. Cloning of a regulatory gene from Streptomyces cattleya and study on its cis-acting element.

    Science.gov (United States)

    Shang, G; Wang, Y

    2000-08-01

    Primers were designed from the highly conserved protein regions of luxl, one of the two component regulatory genes in prokaryotic, and an about 180 bp DNA from Streptomyces cattleya was amplified by PCR. Using this fragment as a probe, Southern hybridization was accomplished with chromosome DNA of S. cattleya, leading to the cloning of the foreign DNA into pBluescript (SK-). DNA sequencing and frame analysis showed an intact ORF consisting of 1800 bp; the G+C composition was 69.3%. Upstream from the ORF was a 249 bp AT rich region, downstream of the ORF several complicated secondary structures were found. DNA-binding assay by gel retardation demonstrated the presence of a protein that specifically bound to the 249 bp AT rich region. The region also showed anomalous electrophoretic mobility at low temperature, like that of a bent DNA molecule, indicating that the region contains a cis-acting element.

  20. Cloning of a regulatory gene from Streptomyces cattleya and study on its cis-acting element

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Primers were designed from the highly conserved protein regions of luxI, one of the two component regulatory genes in prokaryotic, and an about 180 bp DNA from Streptomyces cattleya was amplified by PCR. Using this fragment as a probe, Southern hybridization was accomplished with chromosome DNA of S. cattleya, leading to the cloning of the foreign DNA into pBluescript (SK-). DNA sequencing and frame analysis showed an intact ORF consisting of 1 800 bp; the G+C composition was 69.3%. Upstream from the ORF was a 249 bp AT rich region, downstream of the ORF several complicated secondary structures were found. DNA-binding assay by gel retardation demonstrated the presence of a protein that specifically bound to the 249 bp AT rich region. The region also showed anomalous electrophoretic mobility at low temperature, like that of a bent DNA molecule, indicating that the region contains a cis-acting element.

  1. Cloning of a regulatory gene from Streptomyces cattleya and study on its cis-acting element

    Institute of Scientific and Technical Information of China (English)

    尚广东; 王以光

    2000-01-01

    Primers were designed from the highly conserved protein regions of luxl, one of the two component regulatory genes in prokaryotic, and an about 180 bp DNA from Streptomyces cattleya was amplified by PCR. Using this fragment as a probe, Southern hybridization was accomplished with chromosome DNA of S. cattleya, leading to the cloning of the foreign DNA into pBluescript (SK-). DNA sequencing and frame analysis showed an intact ORF consisting of 1 800 bp; the G+C composition was 69.3%. Upstream from the ORF was a 249 bp AT rich region, downstream of the ORF several complicated secondary structures were found. DNA-binding assay by gel retardation demonstrated the presence of a protein that specifically bound to the 249 bp AT rich region. The region also showed anomalous electrophoretic mobility at low temperature, like that of a bent DNA molecule, indicating that the region contains a c/s-acting element.

  2. Synthesis and electrical transport of single-crystal NH4V3O8 nanobelts.

    Science.gov (United States)

    Mai, L Q; Lao, C S; Hu, B; Zhou, J; Qi, Y Y; Chen, W; Gu, E D; Wang, Z L

    2006-09-21

    Monoclinic NH(4)V(3)O(8) single-crystalline nanobelts with widths of 80-180 nm, thicknesses of 50-100 nm, and lengths up to tens of micrometers have been synthesized at large scale in an ammonium metavanadate solution by a templates/catalysts-free route. Such nanobelts grow along the direction of [010]. The individual NH(4)V(3)O(8) nanobelt exhibits nonlinear, symmetric current/voltage (I/V) characteristics, with a conductivity of 0.1-1 S/cm at room temperature and a dielectric constant of approximately 130. The dominant conduction mechanism is based on small polaron hopping due to ohmic mechanism at low electric field below 249 V/cm due to Schottky emission at medium electric field between 249 and 600 V/cm and due to the Poole-Frenkel emission mechanism at high field above 600 V/cm.

  3. Understanding Market Segments and Competition in the Private Military Industry

    Science.gov (United States)

    2009-12-01

    Kotler , 2008, p . 249). Item 2 and Items 8-10 of the questionnaire attempted to capture the market niche/s that the respondents’ reportedly...Institute Press. Kotler , P ., & Keller, K.L. (2009). Marketing management (13th ed.). Upper Saddle River, NJ: Pearson Prentice Hall. Kruse, K. (2009...Likert scale, and importance scale) and “open-end” (unstructured) questions ( Kotler , 2009, p .137). We applied parts of the Tailored Design Method

  4. Fundamental Capability Portfolio Management: A Study of Developing Systems with Implications for Army Research and Development Strategy

    Science.gov (United States)

    2013-01-01

    The Airborne Standoff Minefield Detection System required the most development funds over time, while the .338 Norma Magnum Lightweight Medium... Norma  Magnum Lightweight Medium  Machine Gun LWMMG 0.25 1 Procured System Name Total  Fiscal  Years RDT&E RDT&E Total  $ MillionsDesignation...Initial Procurement Lightweight Machine Gun (LSAS LMG) M249 Light Machine Gun Weight Reduction In Development 338 Norma Magnum Lightweight

  5. Real-time operating mode with DSSSD detector to search for short correlation ER-alpha chains

    CERN Document Server

    Tsyganov, Yury

    2015-01-01

    Real-time PC based algorithm is developed for DSSSD detector. Complete fusion nuclear reaction natYb+48Ca->217Th is used to test this algorithm at 48Ca beam. Example of successful application of a former algorithm for resistive strip PIPS detector in 249Bk+48Ca nuclear reaction is presented too. Case of alpha-alpha correlations is also under brief consideration.

  6. Thermophysical Properties of Matter - the TPRC Data Series. Volume 14. Master Index - To Materials and Properties

    Science.gov (United States)

    1979-01-01

    2 Cuamg 12 S23 Copper oxides: CuO - 5 s - 8247 - 8 249 - - CU 2 0 2 147 5 76 8 243 8 49C.=O 5 Copper selenide , CuOSe2 1 - - I - Copper ... selenide -copper antimony selenide, mixture 1 1401 Copper allcides: Cu.Si - 13 1211 Cu iSI- - 13 1212 Copper sulfide&: K 6 - - - _- 6 CuaS 2- - - Copper

  7. Exploring the role of information and communication technology on employees' work and family domains / Johannes Willem de Wet

    OpenAIRE

    De Wet, Johannes Willem

    2015-01-01

    Technology has become part of society’s everyday functions, changing rapidly and providing widespread mobility. In South Africa alone, the amount of internet users grew from 8,5 million to 24,9 million in only three years (2011-2014). Currently 90% of these users access this facility from their mobile devices. This statistic illustrates the trend that South Africans are moving towards a continually connected lifestyle, a situation in which information and communication technolo...

  8. Democratization in Albania: The OSCE, NATO and the European Union

    Science.gov (United States)

    2010-06-01

    17 February 2010). 242 John O’Brennan and Esmeralda Gassie, “From Stabilization to Consolidation: Albania State Capacity and Adaptation to European...accessed 5 April 2010). 249 John O’Brennan and Esmeralda Gassie, “From Stabilization to Consolidation: Albania State Capacity and Adaptation to European...John and Esmeralda Gassie. “From stabilization to consolidation: Albania state capacity and adaptation to European Union rules,” Journal of Balkan

  9. The point mutation of p53 gene exon7 in hepatocellular carcinoma from Anhui Province, a non HCC prevalent area in China

    Institute of Scientific and Technical Information of China (English)

    Hu Liu; Yuan Wang; Qing Zhou; Shu-Yu Gui; Xu Li

    2002-01-01

    AIM: In hepatocellular carcinoma (HCC) prevalent areas ofChina, the point mutation of p53 exon7 is highly correlatedwith Hepatitis B virus(HBV) infection and aflatoxin B intake.While in non-HCC-prevalent areas of China, these factorsare not so important in the etiology of HCC. Therefore, thepoint mutation of p.53 exon7 may also be different than thatin HCC-prevalent areas of China. The aim of this study is toinvestigate the status and carcinogenic role of the pointmutation of p53 gene exon7 in hepatocellular carcinoma fromAnhui Province, a non-HCC-prevalent area in China.METHODS: PCR,PCR-SSCP and PCR-RFLP were applied toanalyze the homozygous deletion and point mutation of p53exon7 in HCC samples from Anhui, which were confirmedby DNA sequencing and Genbank comparison.RESULTS: In the 38 samples of hepatocellular carcinoma, nohomozygous deletion of p53 exon7 was detected and pointmutations of p53 exon7 were found in 4 cases, which werefound to be heterozygous mutation of codon 249 With amutation rate of 10.53 %(4/38). The third base mutstion(G→T) of p53 codon 249 was found by DNA sequencing andGenbank comparison.CONCLUSION: The incidence of point mutation of p53 codon249 is lower in hepatocellular carcinoma and theheterozygous mutation of p53 exon7 found in these patientsonly indicate that they have genetic susceptibility to HCC.p53 codon 249 is a hotspot of p53 exon7 point mutation,suggesting that the point mutation of p53 exon 7 may notplay a major role in the carcinogenesis of HCC in AnhuiProvince, a non-HCC-prsvalent area in China.

  10. The Modulation of Polymorphonuclear Neutrophil Function by Cytotoxic Necrotizing Factor Type 1 - Expressing Uropathogenic Escherichia coli

    Science.gov (United States)

    2005-01-01

    cytospin centrifuge and fixed with methanol. The cells were counter stained with Safranin O following fixation and air -dried. The percent of PMNs...final time and centrifuged for 2 min at 9,000 X g. The supernatant was aspirated and the pellet dried under an air stream and then resuspended in...patients." Microbiologia 10(3): 249-56. Bokoch, G. M. (1995). "Regulation of the phagocyte respiratory burst by small GTP- binding proteins." Trends Cell

  11. Reduciblity, Arrhenius plots and the Uroboros Dragon, a reply to the preprint "Correlations in Nuclear Arrhenius-Type Plots" by M.B. Tsang and P. Danielewicz

    CERN Document Server

    Moretto, L G; Phair, L; Wozniak, G J

    1997-01-01

    In a recent preprint by Tsang and Danielewicz, the authors attempt to give alternative or trivial explanations for the reducible and "thermal" nature of the intermediate mass fragment excitation functions reported previously (Phys. Rev. Lett. 74, 1530 (1995), Phys. Lett B 361, 25 (1995), Phys. Rep. 287, 249 (1997)). We demonstrate that their proposed "self-correlation" explanation for linear Arrhenius plots is based upon a flawed autocorrelation analysis involving circular reasoning.

  12. Domain Modeling: NP_060012.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_060012.3 chr1 ADR1 DNA-BINDING DOMAIN FROM SACCHAROMYCES CEREVISIAE, NMR, 25 STR...UCTURES c2adra_ chr1/NP_060012.3/NP_060012.3_holo_242-299.pdb psi-blast 244A,246A,247M,249R,263D,275A,277G,278D,280I,296M,297N _ZN 0 ...

  13. Nucleon structure from 2+1-flavor dynamical DWF ensembles

    CERN Document Server

    Abramczyk, Michael; Lytle, Andrew; Ohta, Shigemi

    2016-01-01

    Nucleon isovector vector- and axialvector-current form factors, the renormalized isovector transversity and scalar charge, and the bare quark momentum and helicity moments of isovector structure functions are reported with improved statistics from two recent RBC+UKQCD 2+1-flavor dynamical domain-wall fermions ensembles: Iwasaki\\(\\times\\)DSDR gauge \\(32^3\\times64\\) at inverse lattice spacing of 1.38 GeV and pion mass of 249 and 172 MeV.

  14. Synthesis of a new element with atomic number Z=117

    Energy Technology Data Exchange (ETDEWEB)

    Oganessian, Yuri Ts. [FLNR-JINR, Russia; Abdullin, F. Sh. [Joint Institute for Nuclear Research, Dubna, Russia; Bailey, P. D. [Oak Ridge National Laboratory (ORNL); Benker, D. E. [Oak Ridge National Laboratory (ORNL); Bennett, M. E. [University of Nevada, Las Vegas; Dmitriev, S. [FLNR-JINR, Russia; Ezold, Julie G. [Oak Ridge National Laboratory (ORNL); Hamilton, J. H. [Vanderbilt University; Henderson, R. [Lawrence Livermore National Laboratory (LLNL); Itkis, M. G. [FLNR-JINR, Russia; Lobanov, Yu. V. [Joint Institute for Nuclear Research, Dubna, Russia; Mezentsev, A. N. [Joint Institute for Nuclear Research, Dubna, Russia; Moody, K. [Lawrence Livermore National Laboratory (LLNL); Nelson, S. L. [Lawrence Livermore National Laboratory (LLNL); Polyakov, A. N. [Joint Institute for Nuclear Research, Dubna, Russia; Porter, C. E. [Oak Ridge National Laboratory (ORNL); Ramayya, A. V. [Vanderbilt University; Riley, F. D. [Oak Ridge National Laboratory (ORNL); Roberto, James B [ORNL; Ryabinin, M. A. [Research Institute of Atomic Reactors, Dimitrovgrad, Russia; Rykaczewski, Krzysztof Piotr [ORNL; Sagaidak, R. N. [Joint Institute for Nuclear Research, Dubna, Russia; Shaughnessy, D. [Lawrence Livermore National Laboratory (LLNL); Shirokovsky, I. V. [Joint Institute for Nuclear Research, Dubna, Russia; Stoyer, M. [Lawrence Livermore National Laboratory (LLNL); Subbotin, V. G. [Joint Institute for Nuclear Research, Dubna, Russia; Sudowe, R. [University of Nevada, Las Vegas; Sukhov, A. M. [Joint Institute for Nuclear Research, Dubna, Russia; Tsyganov, Yu. S. [Joint Institute for Nuclear Research, Dubna, Russia; Utyonkov, V. [FLNR-JINR, Russia; Voinov, A. A. [Joint Institute for Nuclear Research, Dubna, Russia; Vostokin, G. K. [Joint Institute for Nuclear Research, Dubna, Russia; Wilk, P. A. [Lawrence Livermore National Laboratory (LLNL)

    2010-01-01

    The discovery of a new chemical element with atomic number Z=117 is reported. The isotopes 293117 and 294117 were produced in fusion reactions between 48Ca and 249Bk. Decay chains involving eleven new nuclei were identified by means of the Dubna Gas Filled Recoil Separator. The measured decay properties show a strong rise of stability for heavier isotopes with Z111, validating the concept of the long sought island of enhanced stability for super-heavy nuclei.

  15. Grounding the Underground

    Science.gov (United States)

    2013-06-01

    young women , and otherwise indiscriminately killed civilians.249 At the same time, groups of young Filipinos armed with bolo knives and stolen...Griffith translation, Chicago, IL: University of Chicago Press, 1961), 66. “The guerrilla must move among the people as a fish swims in the sea.” 15 Ibid...the problem is laid out.41 Lastly, the motivational frame should issue a call to arms in which the target audience is called upon to take action.42

  16. EST Table: FS768068 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS768068 E_FL_fcaL_47O05_F_0 10/09/28 99 %/249 aa ref|NP_001040336.1| ARP1 actin-re...byx mori] 10/09/08 81 %/246 aa FBpp0282261|DpseGA19410-PA 10/08/28 69 %/245 aa Y53F4B.22#CE35675#WBGene00013168

  17. Preliminary organizational culture scale focused on artifacts.

    Science.gov (United States)

    Bonavia, Tomas

    2006-12-01

    In this preliminary study, an Organizational Culture Scale was developed to assess cultural artifacts according to Schein's typology (1985). It includes a set of cultural artifacts to measure the extent to which an organization is more or less traditional. A total of 249 managers from a range of different companies responded to the items. Preliminary analysis yielded a one-dimensional scale with 14 items with high internal consistency and homogeneity.

  18. Preliminary organizational culture scale focused on artifacts

    OpenAIRE

    Bonavia, Tomas

    2006-01-01

    In this preliminary study, an organizational culture scale was developed to assess cultural artifacts according to Schein´s typology (1985). It includes a set of cultural artifacts to measure the extent to which an organization is more or less traditional. A total of 249 managers from a range of different companies responded to the items. Preliminary analysis yielded a one-dimensional scale with 14 items with high internal consistency and homogeneity.

  19. Dynamic Modeling of the Economic Impacts of a Terrorist Attack using a Radiological Dispersion Device

    Science.gov (United States)

    2009-03-01

    combined, the model uses historical examples of responses from the September 11 attacks, the Three Mile Island and Goiania , Brazil incidents, natural...radiological incidents is gathered from the Goiania , Brazil, Chernobyl, and Three Mile Island incidents. “The tragic radiological accident that occurred...treated for radiation burns, and 249 others were exposed to the cesium 137 radiation. Mass panic ensued across Goiania as the result of the incident

  20. Effects of TBT (Tributyltin) on Marine Organisms: Field Assessment of a New Site-Specific Bioassay System.

    Science.gov (United States)

    1987-12-01

    ditermined at which TBr concentrations significant 10, 11). The index described by Baird (9) and differences occurred. Galtsoff (12) was modified and...4, pp. 1240-1245. fn (9) Baird , R. H. 1958. Measurement of ri V1 condition in mussels and oysters. J. du Conseil. 23:249-257. (21) Waldock, M. J., J...chemistry. x In: G. D. Grice and M. R. Reeve (eds.), Marine Mesocosms: Biological and Chemical Research in z Ecperimental Ecosystems, Springer-Verlag

  1. Other hematopoietic disorders

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    2010371 The incidence and risk factors of late-onset non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation. WU Tao(吴涛),et al.Dept Hematol,Nanfang Hosp,Nanfang Med Univ,Guangzhou 510515.Chin J Hematol 2010;31(4):249-252. Objective To analyze the incidence and the risk factors of late-onset non-infectious

  2. En-Route Care Capability from Point of Injury Impacts Mortality after Severe Wartime Injury

    Science.gov (United States)

    2013-02-01

    thoracotomy, tube or open or needle de- compression; 3. Intraosseous access: sternal, humeral or tibial access sites; 4. Intravenous access: peripheral or...intervention 222 (20.3%) 36 (5.5%) 156 (40.5%) 30 (51.7%) Chest decompression 134 (12.3%) 19 (2.9%) 96 (24.9%) 19 (32.8%) Intraosseous access 255 (23.3%) 39 (6.0...thoracostomy, needle decompression; Intraosseous access = Sternal, humeral, tibial locations; Intravenous access = Peripheral and central access

  3. Optic Nerve Avulsion after Blunt Trauma

    Directory of Open Access Journals (Sweden)

    Hacı Halil Karabulut

    2014-05-01

    Full Text Available Optic nerve avulsion is an uncommon presentation of ocular trauma with a poor prognosis. It can be seen as complete or partial form due to the form of trauma. We assessed the complete optic nerve avulsion in a 16-year-old female patient complaining of loss of vision in her left eye after a traffic accident. (Turk J Ophthalmol 2014; 44: 249-51

  4. Workshop on New Directions in Solid State Power Switches Held at Farmingdale, New York on 28-30 August 1985.

    Science.gov (United States)

    1985-12-24

    TEMPERATURE (K) FIGUk 6 249 I04 E > 10 2 w 101 G L 1013 10 14 13 I of I 10 I1 ", , *~~1 10~10 o GOLD CONCENTRATION (atoms/cm3 ) S=o13 -3 N =10 cm A D...l+p.K.+ , --. J . -.. .L +,,+t+a u .t , - - - .,.+I II i | I +m + , ’ . Aus lee - EE to 10 10 GOLD CONCENTRATION (atomslcm3) 278 e 7, ,r ,%-,---.- L

  5. The Associations between Loss and Posttraumatic Stress and Depressive Symptoms Following Hurricane Ike

    OpenAIRE

    Paul, Lisa A.; Price, Matthew; Gros, Daniel F.; Gros, Kirstin Stauffacher; McCauley, Jenna L.; Resnick, Heidi S.; Acierno, Ron; Ruggiero, Kenneth J.

    2013-01-01

    Disasters can have wide-ranging effects on individuals and their communities. Loss of specific resources (e.g., household contents, job) following a disaster has not been well studied, despite the implications for preparedness efforts and post-disaster interventions. The present study used random-digit-dial methodology to recruit hurricane-affected adults from Galveston and Chambers, TX, counties one year after Hurricane Ike. Data from 1,249 survivors were analyzed to identify predictors of d...

  6. Korea’s Post-Conflict Peace Operations: A Comparative Assessment of Korean Combat Battalions in East Timor and Lebanon

    Science.gov (United States)

    2012-03-01

    with the locals populace (movies, sports games ) - Blue Angel Operation (continued) - Saemaul movement of ‘Homé’ village Oecussi (Oct 2001 ~ Mar...Timor Media Monitoring,” Asia Pacific Solidarity Network, 18 Feb, 2003 49 “Ring the Golden Bell,” a series of quiz competitions, was organized by...ability. 249 The Korean force held events like quiz competitions and speech contests. According to one Korean officer, these were meant “to create in

  7. Antibiotic-coated medical devices: with an emphasis on inflatable penile prosthesis

    Institute of Scientific and Technical Information of China (English)

    R.Abouassaly; D.K.Montague; K.W.Angermeier

    2004-01-01

    One of the most serious complications associated with the use of the inflatable penile prosthesis is infection.This can lead to significant morbidity for the patient, as well as significant health care costs. A number of methods have been used in attempts at minimizing the infection risk, including applying an antibiotic coating to the medical devise. This review aims to evaluate the effectiveness of these products in preventing clinically significant infections.(Asian J Androl 2004 Sep; 6: 249-257)

  8. RP-HPLC法测定怀槐中染料木素和芒柄花黄素含量%RP-HPLC determination of genistein and formononetin in various parts of Maackia amurensis

    Institute of Scientific and Technical Information of China (English)

    黄文哲; 韦佳; 王峥涛; 周荣汉

    2004-01-01

    A method for the determination of genistein and formononetin in Maackia amurensis Rupr. et Maxim. by HPLC was reported. The RP-HPLC methods were used as follow: Hypersil ODS C18 column; The mobil phase is MeOH-1% acetic acid solution (gradient),genistein and formononetin were determined by UV detector at 261 nm and 249nm respectively. The results 2.16% respectively. The method is appropriate for determinaton of genistein and formaononetin in M. amurensis.

  9. Leadtime Variability In Inventory Requirement Projections.

    Science.gov (United States)

    1980-06-30

    tions to the Laplace. This result is important because it verifies an important assumption in the work of Presutti and Trepp (1970). With Laplace...leadtime demand, Presutti and Trepp have already worked out the optimization models. We also found that the normal distribution is a good approximation...is quite an important finding since AFLC would like to use ’lr ., 5 the Presutti- Trepp Model IV (1970, pp. 248-249) which assumes that leadtime demand

  10. 酮康唑乳膏治疗浅部真菌病疗效分析%Efficacy Analysis of Ketoconazole Treat Superficial Mycoses

    Institute of Scientific and Technical Information of China (English)

    钱青; 袁玲玲; 李月花; 翟萍

    2011-01-01

    目的:探讨酮康唑乳膏治疗皮肤浅部真菌病的临床疗效.方法:249例皮肤浅部真菌病患者采用酮康唑乳膏治疗,早晚各1次,连用2~4周,观察临床症状和体征.结果:249例皮肤浅部真菌病患者中,体股癣有效率94.7%;手足癣有效率94.3%;花斑癣有效率97.7%;皮肤念珠菌病有效率95.4%,没有发现不良反应.结论:酮康唑乳膏治疗皮肤浅部真菌病有较高的疗效.%Objective:To discuss clinical efficacy of Ketoconazole cream in the treatment of superficial mycoses.Methods:249 cases of superficial mycoses using ketoconazole cream in the treatment,twice a day, last 2 to 4 weeks,observing clinical symptoms and signs.Results:249 cases of skin in patients with superficial mycoses,efficiency of tinea corporis and cruris is 94.7%;tinea manuum and pedis is 94.3%;pityriasis versicolor isL97.7%;skin candidiasis is 95.4%,no adverse reactions.Conclusion:Ketoconazole cream in the treatment of superficial mycoses have a higher efficacy.

  11. NCFST/IFSH US Army Project (Contract W911NF-09-2-0051, Illinois Institute of Technology)

    Science.gov (United States)

    2012-01-01

    Clostridium botulinum Growth and Toxin Production in Commercially Sterile Foods. Journal of Food Protection. 74(11): 1956-89. 3. Anderson, N.M. and...P.N. Walker. 2011. Quality Comparison of Continuous Steam Sterilization Segmented-Flow Aseptic Processing versus Conventional Canning of Whole and...Publishing. ISBN: 0813816688, pp. 249-261. 5. Duncan, Timothy V. 2011. Applications of Nanotechnology in Food Packaging and Food Safety: Barrier

  12. Narcolepsy and pregnancy

    DEFF Research Database (Denmark)

    Maurovich-Horvat, Eszter; Kemlink, David; Högl, Birgit;

    2013-01-01

    In a retrospective cohort study undertaken in 12 European countries, 249 female narcoleptic patients with cataplexy (n = 216) and without cataplexy (n = 33) completed a self-administrated questionnaire regarding pregnancy and childbirth. The cohort was divided further into patients whose symptoms...... of narcolepsy started before or during pregnancy (308 pregnancies) and those in whom the first symptoms of narcolepsy appeared after delivery (106 pregnancies). Patients with narcolepsy during pregnancy were older during their first pregnancy (P ...

  13. An Overview of Production Systems

    Science.gov (United States)

    1975-10-01

    DISTRIBUTED BY: Matonal Tochnica! Infonu srice U. S. DEPARTMENT OF COMMERCE 028143 Stanford Artificil Inteligence Laboratory October 1975 Memo AIM-271...ORGANIZATION NAMEL AND ADDRESS 18. PROGRAM ELEMENT. PROJECT. TASK Artificial Intelligence Laboratory AE OKUI UBR Stanford University ARPA Order 249...014-64011I j SEC-jRITY CLASSIFICATION OF THIS PAGE (When, Data bHISP011 A Stanford Artificial ktteligncs Laboratory October 1975 Memo AIM-271 Computer

  14. Drug: D05258 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available gonadotropin receptor agonist [HSA:3973] [KO:K04248]; follicle stimulating hormone receptor agonist [HSA:249...O URINARY SYSTEM AND SEX HORMONES G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM G03G GONADOTROPINS AND OTHER OVULATION STIMU...973] [KO:K04248] Serum gonadotrophin [ATC:03GA03] D05258 Serum gonadotrophin (JP16) Follicle stimulating hormone follicle stimu

  15. RDX in Plant Tissue: Leading to Humification in Surface Soils

    Science.gov (United States)

    2013-01-01

    bombing range. Incineration is a fairly quick process but requires excavation and transport , and can spread the contamination further via air-borne...cell compartments in leaves. Planta 209: 239–249. Palmer. W. G., J. R. Beaman, D. M. Walters, and D. A. Creasia. 1997. Bioavailability of TNT...Machler, E. Martinoia, and J. J. Oertli. 1994. Transport of Ascorbic and Dehydroascorbic Acids across Protoplast and Vacuole Membranes Isolated from

  16. The Volume of Blood Shed During the Bleeding Time Correlates with the Peripheral Venous Hematocrit

    Science.gov (United States)

    2007-11-02

    Thtombosis. NY, Gnme-Stration 1974,2:249. 2. The bleeding time. The Lancet 1991,337:1447. 3. Rodgers RPC, Levin J. A critical reappraisal of the bleeding...The bleeding-time and the baematocrit. The Lancet May 4; 1984,997. * ^SSSfSSf ^ ’*" bl00d "* ""’* ’*■» ">te ta ««»bus fixation. Science

  17. Demonstration and Validation of a Regenerated Cellulose Dialysis Membrane Diffusion Sampler for Monitoring Ground Water Quality and Remediation Progress at DoD Sites for Perchlorate and Explosives Compounds

    Science.gov (United States)

    2010-09-01

    Preparation and Mobilization .................................................................. 24  5.5.2 Field Demonstration Sampling Events...pertinent requirements include: 1.III.02.n; 130; 145; 244; 246; 249; 254; 255; and 1701. 4 2.0 TECHNOLOGY 2.1 TECHONOLOGY DESCRIPTION Most...protective mesh. 24 5.5 FIELD TESTING 5.5.1 Field Demonstration Preparation and Mobilization Access to and integrity of the wells to be sampled at

  18. SIAM Conference of Optimization Theory and Applications (4th) Held in Chicago, Illinois on May 11-13, 1992

    Science.gov (United States)

    1992-08-31

    405 Hilgard Ave czyzyklgiems.nwu.edu University Park PA 16802 Los Angeles CA 90024-1481 _ -~ Edward J, Dean Eayrny e , lne Klerk University of...research! tck I Frederick C, Keihn Cart T, KeLley Kenneth R, Kelly 249 S Pugh Street North Carolina State Univ 231 Hazel Blvd State College PA 16801...mccormickEnmtsg. c.da Frederick Martin, Medak Sanjay, Mehrotra Sanjay, Metkote 2103 Stony Run Circle Northwestern University Northwestern University

  19. Annual Historical Review.

    Science.gov (United States)

    1987-01-01

    Development Plan V 41 _ MRSA Field Evaluation on SDC Program V 41 ,-. SMART at AMCCOM V 41 MOP Shop Relocation V 42 M249 Squad Automatic Weapon V 42 Technical... robotics , and measurements and qualification of auto gages at Mississippi Army Ammunition Plant. Major General 0. Decker (retired) conducted an...be telerobotically operated to eliminate human contact with dud ammunition. The Human Engineering Laboratory (HEL) had an ongoing robotic test project

  20. Self-Regulation and Dimensions of Parenting Styles Predict Psychological Procrastination of Undergraduate Students

    OpenAIRE

    Habibeh Mortazanajad; Faride mostafafi; Shahram Vahedi

    2009-01-01

    "n Objective: "n "nPrevious research has linked self regulation and parenting styles separately to academic procrastination. This article investigates the impact of the dimensions of parenting styles, behavioral self regulation and short term self regulation on procrastination of students. "nMethod: A sample of 249 adolescents (174 females and 75 male) aged 19 - 21 years completed measures of Parent as Social Context Questionnaire- Adolescent Report, Self-regulation Questionnaire (SRQ), ...

  1. Multinucleon transfer in the interaction of /sup 58/Ni with /sup 124/Sn around the Coulomb barrier

    Energy Technology Data Exchange (ETDEWEB)

    Chiodi, I.; Lunardi, S.; Morando, M.; Signorini, C. (Padua Univ. (Italy). Ist. di Fisica; Istituto Nazionale di Fisica Nucleare, Padua (Italy)); Fortuna, G.; Starzecki, W.; Stefanini, A.M. (Istituto Nazionale di Fisica Nucleare, Padua (Italy). Lab. di Legnaro); Korschinek, G.; Morinaga, H.

    1982-02-06

    Relative cross-sections for 1, 2, 3, (4, 5) neutron pick-up from a /sup 124/Sn target were measured at THETAsub(l)sub(a)sub(b)=70/sup 0/ with a /sup 58/Ni beam energy of 249 MeV; pairing correlations in the two interacting nuclei and kinematical effects strongly affect the cross-sections; the possibility of observing coherent multipair transfer is discussed.

  2. Koguduse-elu uuendamise lävel / Villem Reiman

    Index Scriptorium Estoniae

    Reiman, Villem

    2008-01-01

    Villem Reimani 1905. aastal kirjutatud nägemus uuenevast kirikust, vabast rahvakirikust. Lisaks eesti rahva olukorrast ja kriitika kõigile poliitilistele, rahvuslikele ning kiriklikele väärnähtustele. Varem ilm.: Postimees 12.11.-29.12.1905, nr. 249, 250, 253, 254, 256, 286. Allkiri: Protestant. Ilm. ka: Mis meist saab? / Villem Reiman. - Tartu : Ilmamaa, 2008, lk 419-437

  3. Design of an electronically tunable millimeter wave Gyrotron Backward Wave Oscillator

    Energy Technology Data Exchange (ETDEWEB)

    Caplan, M.

    1987-01-01

    A non-linear self-consistent computer simulation code is used to analyze the saturated output of the Gyrotron Backward Wave Oscillator (Gyro BWO) which can be used as a tunable driver for a 250 GHz FEL amplifier. Simulations show that the Gyrotron BWO using a Pierce/Wiggler gun configuration can produce at least 10 kW of microwave power over the range 249 GHz to 265 GHz by varying beam voltage alone.

  4. Comparaci??n del valor de pertinencia de las normas contables en EE.UU. versus las normas internacionales de informaci??n financiera: el caso de las American Depositary Receipts

    OpenAIRE

    2015-01-01

    249 p. La presente tesis doctoral analiza la utilidad para los inversionistas de la divulgaci??n de la cifra de resultado cuando las empresas comunican su informaci??n financiera utilizando las Normas Internacionales de Informaci??n Financiera (NIIF) y las normas contables estadounidenses, conocidas como Principios de Contabilidad Generalmente Aceptados o ???U.S. Generally Accepted Accounting Principles??? (U.S. GAAP). Para ello se utiliz?? como muestra de empresas las conocidas como ?...

  5. Drug: D00388 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00388 Drug Triclofos sodium (JP16/USAN); Tricloryl (TN) C2H3Cl3O4P. Na 249.8732 251.3654 D00388.gif Seda...ffecting central nervous system 112 Hypnotics and sedatives, anxiolytics 1129 Oth...NERVOUS SYSTEM N05 PSYCHOLEPTICS N05C HYPNOTICS AND SEDATIVES N05CM Other hypnotics and sedatives N05CM07 Tr

  6. QTL Information Table: 198 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available G249 RG418 pha Luo, L.J., Li, Z.K., Mei, H.W., Shu, Q.Y., Tabien, R., Zhong, D.B., Ying, C.S., Stansel, J.W....eeding Depression and Heterosis in Rice. II. Grain Yield Components. Genetics 158, 1755-1771. http://www.genetics.org/cgi/content/abstract/158/4/1755 ...

  7. Site Evaluation Studies of the Massachusetts Bay Disposal Site for Ocean Disposal of Dredged Material

    Science.gov (United States)

    1988-07-05

    the Bay of Fundy might support as much as 80% of the total summer population south of the Gulf of St . Lawrence . During the high abundance levels of...Suborder Odontoceti (Toothed Whales) Family Delphinidae Family Monodontidae Beluga ( Delphinapterus leucas ) Family Physeteridae Pygmy Sperm Whale (Kogia...in spring and summer extends from the Gulf of St . Lawrence /Nova Scotia region 249 northward (Sergeant 1966; Sutcliffe and Brodie 1977). In fall and

  8. JPRS Report, East Europe

    Science.gov (United States)

    1991-02-12

    municipal organizations. There was a cadre renovation . The different generations of socialists con- solidated their positions on the basis of the...steps leading to the renovation of the Socialist Party. They will establish connections with the leaderships of the other political parties. The...petajoule (3) VILLAMOS ENERGIA (2) 249,7 \\ EGYEB 15,4 (i) SZENW ’ 313,4 FOLDGAZfcs) 411,7 KOOLAJ (6) 424,8 Key: 1. Total, petajoules 2

  9. The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep settings

    OpenAIRE

    Roach, Gregory D.; Reid, Kathryn J; Ferguson, Sally; Dawson, Drew

    2006-01-01

    Background: The aim of the study was to examine the role that melatonin production plays in the regulation of sleep consolidation in a population of shiftworkers working and sleeping in their natural environments.Methods: 253 locomotive engineers (249 male, 4 female, mean age = 39.7 years) participated in the study for a 2-week period whilst working their normal roster patterns. Participants recorded details for all sleep periods in a sleep diary and collected urine samples during each day's ...

  10. Domain Modeling: NP_001833.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001833.1 chr9 Crystal structure of Interleukin-23 c3d85d_ chr9/NP_001833.1/NP_001833....1_apo_39-294.pdb c3d87d_ chr9/NP_001833.1/NP_001833.1_holo_39-294.pdb blast 245R,246Y,247R,248P,249L,250I,275E,276Y,293W MAN,PO4 1 ...

  11. Draft Environmental Impact Statement. Proposed Actions at U.S. Army Kwajalein Atoll

    Science.gov (United States)

    1989-06-12

    The Natural History of Enewetak Atoll . U.S. Department of Energy, Office of Scientific and Technical Information: Oak Ridge, Tennessee. Dion, W. April...pp. 201-249. I Reese, E. S. 1987. Terrestrial Environments and Ecology of Enewetak Atoll . IN: Devaney et al. The Natural History of Enewetak Atoll ...Majuro, Republic of the Marshall Islands. Ristvet, B. L. 1987. Geology and Geohydrology of Enewetak Atoll . IN: Devaney et al. The Natural History of

  12. Multiresidue analytical procedures for pesticides residues in vegetable products; Metodi mutiresiduo per l`analisi di residui di antiparassitari in prodotti vegetali

    Energy Technology Data Exchange (ETDEWEB)

    Gruppo di lavoro per i residui di antiparassitari della Commissione permanente di coordinamento interregionale per i problemi relativi al controllo ufficiale dei prodotti alimentari

    1997-09-01

    Multiresidue methods for pesticide residues in vegetable products, most frequently used by laboratories of the Italian national health service, by the regional and provincial agencies for environmental protection and by the National health institute. The analytical behaviour is presented for 249 pesticides through the different steps of extraction and cleanup, along with data for the gas chromatography (GC), gas chromatography coupled to mass spectrometry (GC/MS) and high performance liquid chromatography coupled to spectrophotometric detector (HPL/UV).

  13. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Certification of Form N-CSR... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter... must include certifications in the form specified in Item 12(a)(2) of Form N-CSR or Item 3 of Form...

  14. A Bibliographic Database for the History of Pilot Training Selection

    Science.gov (United States)

    2011-07-01

    Estudio psicofisiolôgico de la profesiôn de piloto aviador. Revista de Psicologia i Pedagogia, 2, 54-79. Describes test content, scoring...generali e ricerche sperimentali sulla selezione dei piloti di aviazione. Rivista di Psicologia , 25, 180-194. Gemelli, A. (1929). Ricerche sulla...Revista de Psicologia del Trabajo y de las Organizaciones, 20(2), 249-261. Morin, D. P. (1997). Training Air Service Pursuit Pilots in World War I

  15. EST Table: FS938859 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS938859 E_FL_fwgP_53D14_F_0 10/09/28 92 %/249 aa ref|NP_001037309.1| vitellogenin ...rt=VH; Flags: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [B...2654|ref|XP_970210.1| PREDICTED: similar to vitellogenin [Tribolium castaneum] FS939370 fwgP ...

  16. Drug: D05014 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D05014 Drug Mettreleptin (genetical recombination) (JAN); Metreleptin (USAN/INN); Metreleptin... [metabolic homeostasis regulator] Therapeutic category: 2499 leptin [CPD:C18188] analogue N-methionylleptin (human) leptin...ans 24 Hormones 249 Miscellaneous 2499 Others D05014 Mettreleptin (genetical recombination) (JAN); Metreleptin...s Class I cytokine receptors (hematopoietin family receptors) leptin receptor [HSA:3953] [KO:K05062] Metreleptin D05014 Metreleptin (USAN/INN) CAS: 186018-45-1 PubChem: 47206741 ...

  17. Risk Factors for Treatment Failure in Smokers: Relationship to Alcohol Use and to Lifetime History of an Alcohol Use Disorder

    OpenAIRE

    Leeman, Robert F.; McKee, Sherry A.; Toll, Benjamin A.; Krishnan-Sarin, Suchitra; Cooney, Judith L.; Makuch, Robert W.; O’Malley, Stephanie

    2008-01-01

    Little is known about the impact of alcohol involvement on smoking cessation relapse or possible mechanisms for these associations. We addressed these issues using data from a randomized clinical trial of 2 types of framed messages (gain vs. loss) in conjunction with open label sustained-release (SR) bupropion (Toll et al., 2007) (N = 249). Participants were categorized according to whether or not they were diagnosed with a lifetime alcohol use disorder (AUD; i.e., current or past alcohol abu...

  18. Evaluation of Data Processing Techniques for Unobtrusive Gait Authentication

    Science.gov (United States)

    2014-03-01

    characteristics of an individual, distinguishable from those of other individuals. Originally described by Bianchi et al. [10], the different biomechanical ...devices,” Pervasive Computing, K. Fishkin, B. Schiele, P. Nixon, and A. Quigley, Eds, Berlin, DE: Springer Berlin Heidelberg, Lecture Notes in Computer...gait recognition,” Biometrics, A.K. Jain, R. Bolle, and S. Pankanti, Eds. New York, NY: Springer USA, ch. 11, pp. 231–249, 1996. [14] J. Han and B

  19. Inserting Agility in System Development

    Science.gov (United States)

    2012-07-01

    Agile IT Acquisition, IT Box, Scrum Inserting Agility in System Development Matthew R. Kennedy and Lt Col Dan Ward, USAF With the fast-paced nature...1,700 individuals and 71 countries, found Scrum and eXtreme Programming to be the most widely followed method- ologies (VersionOne, 2007). Other...University http://www.dau.mil 259 Defense ARJ, July 2012, Vol. 19 No. 3 : 249–264 Scrum Scrum is a framework used for project management, which is

  20. Novel codon insert in HIV type 1 clade B reverse transcriptase associated with low-level viremia during antiretroviral therapy.

    Science.gov (United States)

    Chaillon, Antoine; Gianella, Sara; Vazquez, Homero; Ignacio, Caroline; Zweig, Adam C; Richman, Douglas D; Smith, Davey M

    2014-02-01

    We investigated the pol genotype in two phylogenetically and epidemiologically linked partners, who were both experiencing persistent low-level viremia during antiretroviral therapy. In one partner we identified a new residue insertion between codon 248 and 249 of the HIV-1 RNA reverse transcriptase (RT) coding region (HXB2 numbering). We then investigated the potential impact of identified mutations in RT and antiretroviral binding affinity using a novel computational approach.

  1. The Coast Artillery Journal. Volume 66, Number 1, January 1927

    Science.gov (United States)

    1927-01-01

    Monroe, Virginia Fort Barrancas , Florida Fort Casey, Washington Total 351 119 40 510 During the year 1925, 318 graduates of the eighteen C~ast Artil...144 Fort Monroe, Virginia 437 Fort Barrancas , Florida 249 Fort Scott, Califomia . 106 Fort Worden, Washington 26 Total 1206 r. National Guard and...organizations will proceed from Camp Upton to the points selected hy the umpire and halt in march formation on the road. Organization commanders

  2. GEOCHRONOMETRY & ISOTOPE GEOLOGY

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>20080453 Gu Zhaoyan(Institute of Geology and Geophysics,Chinese Academy of Sciences,Beijing 100029);Guo Zhengtang 10 Be Concentration Relation to Chemical Compositions of Chinese Loess and Red Clay as a Potential Dating Method(Quaternary Sciences,ISSN1001-7410,CN11-2708/P,26(2),2006,p.244-249,3 illus.,1 table,21 refs.)

  3. Relations of sex, age, perceived fitness, and aerobic activity with social physique anxiety in adults sixty years and older.

    Science.gov (United States)

    Lanning, Beth A; Bowden, Rodney G; Owens, Robin; Massey-Stokes, Marilyn

    2004-12-01

    Self-reported physical activity, and perceived fitness were examined to assess their effects on social physique anxiety in a sample of older individuals (N= 249; M age=70.4 yr., SD=8.2). Participants reported their fitness as "average" to "above average." There were no significant effects of perceived fitness or age on social physique anxiety scores. The women had significantly higher social physique anxiety scores than the men.

  4. Comment on 'Finding viscosity of liquids from Brownian motion at students' laboratory' and 'Brownian motion using video capture'

    Energy Technology Data Exchange (ETDEWEB)

    Greczylo, Tomasz; Debowska, Ewa [Institute of Experimental Physics, Wroclaw University, pl. Maxa Borna 9, 50-204 Wroclaw (Poland)

    2007-09-15

    The authors make comments and remarks on the papers by Salmon et al (2002 Eur. J. Phys. 23 249-53) and their own (2005 Eur. J. Phys. 26 827-33) concerning Brownian motion in two-dimensional space. New, corrected results of calculations and measurements for students' experiments on finding the viscosity of liquids from Brownian motion are presented. (letters and comments)

  5. Possible Way to Synthesize Superheavy Element Z=117

    OpenAIRE

    Zhao-Qing, Feng; Gen-Ming, Jin; Ming-Hui, Huang; Zai-Guo, Gan; Nan, Wang; Jun-Qing, Li

    2007-01-01

    Within the framework of the dinuclear system model, the production of superheavy element Z=117 in possible projectile-target combinations is analyzed systematically. The calculated results show that the production cross sections are strongly dependent on the reaction systems. Optimal combinations, corresponding excitation energies and evaporation channels are proposed in this letter, such as the isotopes ^{248,249}Bk in ^{48}Ca induced reactions in 3n evaporation channels and the reactions ^{...

  6. Synthesis of a new element with atomic number Z = 117.

    Science.gov (United States)

    Oganessian, Yu Ts; Abdullin, F Sh; Bailey, P D; Benker, D E; Bennett, M E; Dmitriev, S N; Ezold, J G; Hamilton, J H; Henderson, R A; Itkis, M G; Lobanov, Yu V; Mezentsev, A N; Moody, K J; Nelson, S L; Polyakov, A N; Porter, C E; Ramayya, A V; Riley, F D; Roberto, J B; Ryabinin, M A; Rykaczewski, K P; Sagaidak, R N; Shaughnessy, D A; Shirokovsky, I V; Stoyer, M A; Subbotin, V G; Sudowe, R; Sukhov, A M; Tsyganov, Yu S; Utyonkov, V K; Voinov, A A; Vostokin, G K; Wilk, P A

    2010-04-09

    The discovery of a new chemical element with atomic number Z=117 is reported. The isotopes (293)117 and (294)117 were produced in fusion reactions between (48)Ca and (249)Bk. Decay chains involving 11 new nuclei were identified by means of the Dubna gas-filled recoil separator. The measured decay properties show a strong rise of stability for heavier isotopes with Z > or = 111, validating the concept of the long sought island of enhanced stability for superheavy nuclei.

  7. Complex signal amplitude analysis for complete fusion nuclear reaction products

    CERN Document Server

    Tsyganov, Yu S

    2015-01-01

    A complex analysis has been performed on the energy amplitude signals corresponding to events of Z=117 element measured in the 249Bk+48Ca complete fusion nuclear reaction. These signals were detected with PIPS position sensitive detector. The significant values of pulse height defect both for recoils (ER) and fission fragments (FF) were measured. Comparison with the computer simulations and empirical formulae has been performed both for ER and FF signals.

  8. Advanced Casting Technology

    Science.gov (United States)

    1982-08-01

    Zusatz seltener Erden - Giesserei Pr., 1977, p. 249-262. 32) Henrichs, L. U. Hielscher - Das Fliessverhalten erstarrender Aluminium-Gusswerkstoffe als...necessairement associees a des fissures ; elles sont alors parfois difficiles a detecter lors du controle ultrasons et peuvent conduire a des ruptures catastro...controle ultrasons . Nota : Nous avons egalement observe qu’une zone equiaxe donne lieu a une variation sensible de I’attenuation lors d’un sondage

  9. 光电子技术

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    <正> 0507669光子学设计工具:应对挑战=Design Tools for Photon-ics:Rising to the Challenge.[刊,英]/Trevor Benson,Phillip Sewell//IEEE LEOS Newsletter.—2004,18(1).—5-8(E)0507670磁光技术=Magneto-optical technologies[刊,英]/Proberecording//Journal of Electronic Materials.—2002,249(3).—413(E)

  10. Discovery of Novel Drugs to Improve Bone Health in Neurofibromatosis Type 1: The Wnt/Beta-Catenin Pathway in Fracture Repair and Pseudarthrosis

    Science.gov (United States)

    2015-08-01

    neurofibromatosis. 4 To identify agents that inhibit beta-catenin signaling, we undertook a high throughput screen using mesenchymal cells exhibiting...Med 2007, 4:e249. [3] Poon R HH, Wei X, Pan J, and Alman BA: A high throughput screen identifies Nefopam as targeting cell proliferation in β...AWARD NUMBER: W81XWH-13-1-0113 TITLE: Discovery of Novel Drugs To Improve Bone Health in Neurofibromatosis Type 1: The Wnt/Beta-Catenin

  11. Descriptions of Zavortinkius, a New Subgenus of Aedes, and the Eleven Included Species from the Afrotropical Region (Diptera: Culicidae)

    Science.gov (United States)

    1999-01-01

    in laboratory experiments, as a potential vector of chikungunya virus. Uganda S virus was probably isolated from either Ae. longipalpis or Ae...basoventral area. Egg. Gillett (1955:249) reported the following for eight batches of fixed eggs from the Zika Forest near Entebbe, Uganda “. . . eggs of...Bwamba County, Mongiro (Lumsden 1952); Entebbe, Bwamba County, Semliki Forest (Haddow 1961); Zika Forest, near Entebbe (Gillett 1955; Haddow and

  12. Proceedings from the ETS and ARI Emotional Intelligence Workshop held in Princeton, New Jersey on November 13-15, 2003. Volume 2. Sessions 3 and 4

    Science.gov (United States)

    2003-11-01

    assessing with psychopathy ? DR. JAMES: Well Bob Hogan tells me it’s pretty high, so I would suspect with the implicit paranoia that goes through a lot...disorders; 4) somatoform disorders; 5) psychological factors with somatic disorders; 6) eating disorders; 249 patients completed treatment • TAS-20, LEAS...10-item), STAI, SCL-90 administered at onset and end of treatment (2-3 months) • Multi-modal treatment : psychodynamically-oriented individual and

  13. Functions and Mechanisms of Sleep in Flies and Mammals

    Science.gov (United States)

    2009-10-01

    International Mass Spectrom etry Conference; Bremen, Germany: Oral presentation, September 2009. th Tissue Prep aration for the in situ MALDI MS Im...Muscarinic and GABAA receptors modulate acetylcholine release in feline basal forebrain. Eur J Neurosci 17:249-259. Birren Personnel Susan Birren...Vertes, 2004; McDermott et al. 2003). Secondly, gene expression studies of sleep were limited by the use of tissue homogenates that dilute changes in

  14. Libros colombianos raros y curiosos: abril de 1964

    Directory of Open Access Journals (Sweden)

    Ignacio Rodríguez Guerrero

    1964-04-01

    Full Text Available El documento presenta la reseña del título: C. COLLODl (1826-1890.-Las aventuras de Pinoquio. Historia de un Títere. Traducida directamente del italiano para "La Tribuna" y editada por Antonio José Restrepo (1855-1933. Ilustrada por E. Mazzanti y G. Esperón. Imprenta de "La Tribuna" editorial. Bogotá, 1913. VII, 249 págs. 21 % x 16 ctms.

  15. Filtering of Systems with Nonlinearities

    Science.gov (United States)

    1982-03-01

    IEEE Transactions on Automatic Control , Vol. AC - 15, No. 1, February -1970, 74-81. 41 .’ w 7, 1.%U.-.. j...1972, 439 - 448. •IA 35. D. T. Magill, ’"ptimal Adaptive Estimation of Sampled Stochastic I .,"* , Processes," IEEE Transactions on Automatic Control , Vol...F. L. Sims, "Performance Measure for Adaptive Kalman Estimators," IEEE Transactions on Automatic Control , April 1970, pp. 249-250.

  16. Optimization of the Medium for the Production of Extracellular Amylase by the Pseudomonas stutzeri ISL B5 Isolated from Municipal Solid Waste

    Science.gov (United States)

    Dutta, Prajesh; Deb, Akash

    2016-01-01

    The management of municipal solid waste is one of the major problems of the present world. The use of microbial enzymes for sustainable management of the solid waste is the need of the time. In the present study, we have isolated a potent amylase producing strain (ISL B5) from municipal solid waste. The strain was identified as Pseudomonas stutzeri (P. stutzeri) both biochemically and by 16S rDNA sequencing. The optimization studies revealed that the strain ISL B5 exhibited maximum activity in the liquid media containing 2% starch (2.77 U/ml), 0.8% peptone (2.77 U/ml), and 0.001% Ca2+ ion (2.49 U/ml) under the pH 7.5 (2.59 U/ml), temperature 40°C (2.63 U/ml), and 25 h of incubation period (2.49 U/ml). The highest activity of crude enzyme has also been optimized at the pH 8 (2.49 U/ml). PMID:28096816

  17. Prevalence of selected sexually and blood-borne infections in Injecting drug abuser inmates of bandar abbas and roodan correction facilities, Iran, 2002

    Directory of Open Access Journals (Sweden)

    Parivash Davoodian

    2009-10-01

    Full Text Available Human Immunodeficiency Virus (HIV and other blood borne viral infections like hepatitis B virus (HBV and hepatitis C virus (HCV are major health issues especially in young and growing population of developing countries. All around the globe correctional facilities are known as potential source of spreading such disease. During summer 2002, HIV, HCV antibodies, hepatitis B surface (HBs antigen and rapid plasma reagin (RPR test were checked in venous blood samples of 252 injecting drug abuser prisoners from correctional facilities in southern Iran. Overall HIV, HCV and HBV infection rate was 15.1% (38/249, 64.8% (163/249, and 4.7% (12/249, respectively. HCV infection rate of HIV positive cases was 94% (35/38. All RPR results were negative. Duration of previous drug abuse and imprisonment were correlated with HIV and HCV infection (p value = 0.0003 and 0.015 & p value =0.02 and 0.02. Considering the higher prevalence of HIV and HCV infection in correctional facilities compared to general population of Iran, warrants immediate multidisciplinary approaches targeted at controlling further spread of these infections primarily among prisoners and secondarily preventing them to act as carrier to general population.

  18. Comparing the pharmacokinetics of doxylamine/pyridoxine delayed-release combination in nonpregnant women of reproductive age and women in the first trimester of pregnancy.

    Science.gov (United States)

    Matok, Ilan; Clark, Shannon; Caritis, Steve; Miodovnik, Menachem; Umans, Jason; Hankins, Gary; Koren, Gideon

    2013-03-01

    Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent clearances (CL) of doxylamine and pyridoxal 5'-phosphate (PLP; the active metabolite of vitamin B(6) ) during the first-trimester pregnancy in women who participated in a Diclectin randomized trial were compared with those of healthy, adult, nonpregnant women who participated in a voluntary PK trial. Eighteen nonpregnant women were compared with 50 pregnant women who were treated with Diclectin. There was no difference in the apparent CL of doxylamine in women in their first trimester of pregnancy when compared with nonpregnant women on day 4 (median = 196.7 vs 249.5 mL/h/kg, respectively, P = .065), day 8 (median = 248.4 vs 249.5 mL/h/kg, respectively, P = .82), and day 15 (median = 200.9 vs 249.5 mL/h/kg, respectively, P = .55). No difference was found in the apparent CL of PLP on day 15 (median = 342.3 vs 314.7 mL/h/kg, respectively, P = .92). There was no pregnancy-induced effect in the apparent CL of either doxylamine or PLP in women during the first trimester of pregnancy despite the existence of morning sickness.

  19. Investigation on Internet addiction disorder in adolescents in Anhui, People’s Republic of China

    Science.gov (United States)

    Chen, Yan; Kang, Yaowen; Gong, Weizhi; He, Lianping; Jin, Yuelong; Zhu, Xiaoyue; Yao, Yingshui

    2016-01-01

    Background and aim The purpose of this study was to describe the characteristics and prevalence of Internet addiction (IA) in adolescents so as to provide a scientific basis for the communities, schools, and families. Methods We conducted a survey by randomized cluster sampling on 5,249 students, grades ranging from 7 to 12, in Anhui province, People’s Republic of China. The questionnaire consisted of general information and IA test. Chi-square test was used to compare the status of IA disorder (IAD). Results In our results, the overall detection rate of IAD and non-IAD in students was 8.7% (459/5,249) and 76.2% (4,000/5,249), respectively. The detection rate of IAD in males (12.3%) was higher than females (4.9%). The detection rate of IAD was statistically different between students from rural (8.2%) and urban (9.3%) areas, among students from different grades, between students from only-child families (9.5%) and non-only-child families (8.1%), and among students from different family types. Conclusion Prevalence of IA is high among Chinese adolescents. IAD has more effect on male students, single-child families, single-parent families, and higher grade students. We should take more care of male students, only-child students, and students living with their fathers, and related education should be strengthen for susceptible subjects of IDA. PMID:27621633

  20. Optimization of the Medium for the Production of Extracellular Amylase by the Pseudomonas stutzeri ISL B5 Isolated from Municipal Solid Waste

    Directory of Open Access Journals (Sweden)

    Prajesh Dutta

    2016-01-01

    Full Text Available The management of municipal solid waste is one of the major problems of the present world. The use of microbial enzymes for sustainable management of the solid waste is the need of the time. In the present study, we have isolated a potent amylase producing strain (ISL B5 from municipal solid waste. The strain was identified as Pseudomonas stutzeri (P. stutzeri both biochemically and by 16S rDNA sequencing. The optimization studies revealed that the strain ISL B5 exhibited maximum activity in the liquid media containing 2% starch (2.77 U/ml, 0.8% peptone (2.77 U/ml, and 0.001% Ca2+ ion (2.49 U/ml under the pH 7.5 (2.59 U/ml, temperature 40°C (2.63 U/ml, and 25 h of incubation period (2.49 U/ml. The highest activity of crude enzyme has also been optimized at the pH 8 (2.49 U/ml.

  1. Relation of Smoking with Fibrinogenic Bβ-chain Gene Polymorphisms and its Clinical Index in Han Male Retirees of Tangsham%唐山市汉族退休男性吸烟与纤维蛋白原临床指标及其Bβ链基因多态性的相关性

    Institute of Scientific and Technical Information of China (English)

    王淑娟; 许亚茹; 元小冬; 李静; 杨娜

    2012-01-01

    目的 研究唐山市汉族退休男性吸烟与纤维蛋白原(Fg)Bβ链位点基因多态性和血浆Fg水平及其聚合功能的关系.方法 选取唐山市开滦集团汉族退休男性职工890人作为调查对象,均抽取清晨空腹静脉血测定白细胞介素(IL)、血浆Fg水平和纤维蛋白单体聚合反应速率(FMPV)、最大光密度Amax)、FMPV/Amax 等反映Fg聚合功能的指标,应用聚合酶链反应-限制性内切酶片段长度多态性技术检测FgBβ链-854G/A、-455G/A、-249C/T、-148CT、448G/A和Bcl-1G/A6个位点的基因多态性.结果 男性吸烟和不吸烟人群均表现为FgBβ-854位点变异基因型者的血浆Fg系列指标高于野生基因型人群,差异有统计学意义(P<0.05).FgBβ-249 位点变异基因型人群中男性吸烟者的血浆Fg水平、FMPV 及FMPV/Amax均明显高于不吸烟人群,差异有统计学意义(P<.05).结论 FgBβ-854基因多态性位点是影响血浆Fg水平和分子活性功能表达的重要基因位点.吸烟可能与Fg Bβ-249基因型相互作用而使血浆Fg水平升高,并可能影响Bβ-854基因型表达而使血浆Fg分子活性功能增强.%Objective To study the conelation of smoking in Han male retiree of Tangshan with Bβ-854G/A, -455G/A, -249C/T, -148C/T, 448G/A, Bcl-IG/A gene polymorphisms of fibrinogen(Fg), plasma Fg concentration and molecular reactivity. Methods 890 Han male retirees from Tangshan Kailuan Corporation were enrolled. All subjects were phlebotomized in the early morning to measure serum interleukin(IL), Fg concentration, fibrin monomer polymerized velocity(FMPV), absorbance maximum (Amax) and FMPV/Amax, furthermore, to detect six loci of the gene polymorphisms. The characters of the gene polymorphisms and functional expression of Fg based on smoking status were analyzed. Results In both the groups, the serial indexes of Fg with mutated genotype of Bβ-854 were all higher than those with wild genotypes ( P<0.05 ); Fg concentration, FMPV

  2. Investigation on Internet addiction disorder in adolescents in Anhui, People’s Republic of China

    Directory of Open Access Journals (Sweden)

    Chen Y

    2016-08-01

    Full Text Available Yan Chen,1 Yaowen Kang,2 Weizhi Gong,3 Lianping He,1 Yuelong Jin,1 Xiaoyue Zhu,1 Yingshui Yao1 1School of Public Health, Wannan Medical College, Wuhu, Anhui, People’s Republic of China; 2Fushun Administrative College, Fushun, Liaoning, People’s Republic of China; 3Guangdong Polytechnic of Industry and Commerce, Guangzhou, People’s Republic of China Background and aim: The purpose of this study was to describe the characteristics and prevalence of Internet addiction (IA in adolescents so as to provide a scientific basis for the communities, schools, and families.Methods: We conducted a survey by randomized cluster sampling on 5,249 students, grades ranging from 7 to 12, in Anhui province, People’s Republic of China. The questionnaire consisted of general information and IA test. Chi-square test was used to compare the status of IA disorder (IAD.Results: In our results, the overall detection rate of IAD and non-IAD in students was 8.7% (459/5,249 and 76.2% (4,000/5,249, respectively. The detection rate of IAD in males (12.3% was higher than females (4.9%. The detection rate of IAD was statistically different between students from rural (8.2% and urban (9.3% areas, among students from different grades, between students from only-child families (9.5% and non-only-child families (8.1%, and among students from different family types.Conclusion: Prevalence of IA is high among Chinese adolescents. IAD has more effect on male students, single-child families, single-parent families, and higher grade students. We should take more care of male students, only-child students, and students living with their fathers, and related education should be strengthen for susceptible subjects of IDA. Keywords: adolescents, addictive behavior, Internet, health surveys 

  3. Study on hydrogen assisted cracking susceptibility of HSLA steel by implant test

    Directory of Open Access Journals (Sweden)

    Gopa Chakraborty

    2016-12-01

    Full Text Available DMR-249A is an indigenously developed high strength low alloy steel for Indian ship building industry for making ship-hull and is extensively used in the construction of war ships and submarines. Welding electrodes conforming to SFA 5.5 AWS E8018 C1 has been indigenously developed for welding of this steel using shielded metal arc welding process. In the present study, susceptibility to hydrogen assisted cracking of DMR-249A steel welds made using this electrode has been assessed using implant test. Implant tests were conducted using this electrode at two different levels of diffusible hydrogen, measured using gas chromatography technique. It is observed that both the steel and the welding consumable are not susceptible to hydrogen assisted cracking even with a high diffusible hydrogen level of 9 mL/100g of weld metal. In implant tests, specimen did not fracture even after loading to stress levels higher than the yield strength of the base metal. The good resistance of this steel and the welding consumable, even with high levels of diffusible hydrogen, is attributed to absence of a susceptible microstructure in both the weld metal and heat affected zone. Hence, this study shows that, in the absence of a susceptible microstructure, hydrogen assisted cracking is unlikely to occur even if hydrogen level is high. It also confirms that in welding of DMR-249A with indigenously developed E8018 C1 electrode, hydrogen assisted cracking is not a concern and no preheating is required to avoid it during welding.

  4. Association of Body Mass Index and Mortality in Japanese Diabetic Men and Women Based on Self-Reports: The Japan Collaborative Cohort (JACC Study

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    Yasuhiko Kubota

    2015-08-01

    Full Text Available Background: The association between body mass index (BMI and mortality among Asian diabetic people, especially with respect to the obesity paradox (ie, higher BMI is associated with lower mortality risk, remains unresolved. Methods: We followed a cohort of 3851 self-reported Japanese diabetics (2115 men and 1736 women in the Japan Collaborative Cohort Study from 1988–1990 through 2009. Individuals were aged 40 to 79 years and free from a history of cardiovascular disease, cancer, renal disease, or tuberculosis. BMI was grouped into the following four categories: <20.0, 20.0–22.9, 23.0–24.9, and ≥25.0 kg/m2. Results: During 54 707 person-years of follow-up, 1457 deaths from all causes, 445 from cardiovascular disease, 421 from cancer, 43 from renal disease, and 148 from infectious disease were documented. Mortality from all causes, cardiovascular disease, cancer, and renal disease showed L-shaped associations with BMI. Compared to diabetics with BMI of 20.0–22.9 kg/m2, those with BMIs of 23.0–24.9 kg/m2 and ≥25.0 kg/m2 had lower risks of mortality from infectious disease (ie, obesity paradox. The multivariable HRs for mortality from infectious disease were 0.50 (95% confidence interval, 0.31–0.81 and 0.51 (95% confidence interval, 0.32–0.82 among participants with BMIs of 23.0–24.9 kg/m2 and ≥25.0 kg/m2, respectively. Similar results were observed after stratification by smoking status and age and exclusion of early deaths. Conclusions: We observed L-shaped associations between BMI and mortality from all causes, cardiovascular disease, cancer, and renal disease, while the association between BMI and mortality from infectious disease manifested the obesity paradox.

  5. Comparison of the Efficacy of Everolimus-Eluting Stents Versus Drug-Eluting Balloons in Patients With In-Stent Restenosis (from the RIBS IV and V Randomized Clinical Trials).

    Science.gov (United States)

    Alfonso, Fernando; Pérez-Vizcayno, María José; García Del Blanco, Bruno; García-Touchard, Arturo; Masotti, Mónica; López-Minguez, José R; Iñiguez, Andrés; Zueco, Javier; Velazquez, Maite; Cequier, Angel; Lázaro-García, Rosa; Martí, Vicens; Moris, César; Urbano-Carrillo, Cristobal; Bastante, Teresa; Rivero, Fernando; Cárdenas, Alberto; Gonzalo, Nieves; Jiménez-Quevedo, Pilar; Fernández, Cristina

    2016-02-15

    Treatment of patients with in-stent restenosis (ISR) remains a challenge. This study sought to compare the efficacy of everolimus-eluting stents (EESs) and drug-eluting balloons (DEBs) with paclitaxel in patients with ISR. A pooled analysis of the Restenosis Intra-Stent of Drug-Eluting Stents: Drug-Eluting Balloon vs Everolimus-Eluting Stent (RIBS IV) and Restenosis Intra-Stent of Bare-Metal Stents: Drug-Eluting Balloon vs Everolimus-Eluting Stent (RIBS V) randomized trials was performed using patient-level data. In both trials, EESs were compared with DEBs in patients with ISR (RIBS V included 189 patients with bare-metal ISR; RIBS IV included 309 patients with drug-eluting ISR). Inclusion and exclusion criteria were identical in both trials. A total of 249 patients were allocated to EES and 249 to DEB. Clinical follow-up at 1 year was obtained in all (100%) patients and late angiography (median 249 days) in 91% of eligible patients. Compared with patients treated with DEBs, patients treated with EESs obtained better short-term results (postprocedural minimal lumen diameter 2.28 ± 0.5 vs 2.12 ± 0.4 mm, p stent type and treatment effects. At 1-year clinical follow-up, the composite of cardiac death, myocardial infarction, and target vessel revascularization was significantly reduced in the EES arm (8.8% vs 14.5%, p = 0.03; hazard ratio 0.59, 95% CI 0.31 to 0.94) mainly driven by a lower need for target vessel revascularization (6% vs 12.4%, p = 0.01, hazard ratio 0.46, 95% CI 0.25 to 0.86). This pooled analysis of the RIBS IV and RIBS V randomized trials demonstrates the superiority of EES over DEB in the treatment of patients with ISR.

  6. Genetic diversity among some canola cultivars as revealed by RAPD, SSR and AFLP analyses.

    Science.gov (United States)

    Moghaieb, Reda E A; Mohammed, Etr H K; Youssief, Sawsan S

    2014-08-01

    To assess the genetic diversity among four canola cultivars (namely, Serw-3, Serw-4, Misser L-16 and Semu 249), random amplified polymorphic DNA (RAPD), simple sequence repeat polymorphism (SSR) and amplified fragment length polymorphism (AFLP) analyses were performed. The data indicated that all of the three molecular markers gave different levels of polymorphism. A total of 118, 31 and 338 markers that show 61, 67.7 and 81 % polymorphism percentages were resulted from the RAPD, SSR and AFLP analyses, respectively. Based on the data obtained the three markers can be used to differentiate between the four canola cultivars. The genotype-specific markers were determined, 18 out of the 72 polymorphic RAPD markers generated were found to be genotype-specific (25 %). The highest number of RAPD specific markers was scored for Semu 249 (15 markers), while Serw-4 scored two markers. On the other hand, Serw-3 scored one marker. The cultivar Semu 249 scored the highest number of unique AFLP markers, giving 57 unique markers, followed by Misser L-16 which was characterized by 40 unique AFLP markers, then Serw-3 giving 31 unique markers. While Serw-4 was characterized by the lowest number producing 14 unique positive markers. The dendrogram built on the basis of combined data from RAPD, SSR and AFLP analysis represents the genetic distances among the four canola cultivars. Understanding the genetic variability among the current canola cultivars opens up a possibility for developing a molecular genetic map that will lead to the application of marker-assisted selection tools in genetic improvement of canola.

  7. In vitro residual activity of phenylalanine hydroxylase variants and correlation with metabolic phenotypes in PKU.

    Science.gov (United States)

    Trunzo, Roberta; Santacroce, Rosa; Shen, Nan; Jung-Klawitter, Sabine; Leccese, Angelica; De Girolamo, Giuseppe; Margaglione, Maurizio; Blau, Nenad

    2016-12-05

    Hyperphenylalaninemias (HPAs) are genetic diseases predominantly caused by a wide range of variants in the phenylalanine hydroxylase (PAH) gene. In vitro expression analysis of PAH variants offers the opportunity to elucidate the molecular mechanisms involved in HPAs and to clarify whether a disease-associated variant is genuinely pathogenic, while investigating the severity of a metabolic phenotype, and determining how a variant exerts its deleterious effects on the PAH enzyme. To study the effects of gene variants on PAH activity, we investigated eight variants: c.611A>G (p.Y204C), c.635T>C (p.L212P), c.746T>C (p.L249P), c.745C>T (p.L249F), c.809G>A (p.R270K), c.782G>C (p.R261P), c.587C>A (p.S196Y) and c.1139C>T (p.T380M), associated with different phenotypic groups. Transient expression of mutant full-length cDNAs in COS-7 cells yielded PAH proteins with PAH activity levels between 7% and 51% compared to the wild-type enzyme. With one exception (p.Y204C, which had no significant impact on PAH function), lower PAH activity was associated with a more severe phenotype (e.g. p.L249P with 7% PAH activity, 100% of classic PKU and no BH4 responsiveness), while higher activity correlated with milder phenotypes (e.g. p.T380M with 28% PAH activity, 97% of mild HPA and 83% of BH4 responsiveness). The results of the in vitro residual PAH activity have major implications, both for our understanding of genotype-phenotype correlations, and thereby existing inconsistencies, but also for the elucidation of the molecular basis of tetrahydrobiopterin (BH4) responsiveness.

  8. Study on hydrogen assisted cracking susceptibility of HSLA steel by implant test

    Institute of Scientific and Technical Information of China (English)

    Gopa CHAKRABORTY; R. REJEESH; S.K. ALBERT

    2016-01-01

    DMR-249A is an indigenously developed high strength low alloy steel for Indian ship building industry for making ship-hull and is extensively used in the construction of war ships and submarines. Welding electrodes conforming to SFA 5.5 AWS E8018 C1 has been indigenously developed for welding of this steel using shielded metal arc welding process. In the present study, susceptibility to hydrogen assisted cracking of DMR-249A steel welds made using this electrode has been assessed using implant test. Implant tests were conducted using this electrode at two different levels of diffusible hydrogen, measured using gas chromatography technique. It is observed that both the steel and the welding consumable are not susceptible to hydrogen assisted cracking even with a high diffusible hydrogen level of 9 mL/100g of weld metal. In implant tests, specimen did not fracture even after loading to stress levels higher than the yield strength of the base metal. The good resistance of this steel and the welding consumable, even with high levels of diffusible hydrogen, is attributed to absence of a susceptible microstructure in both the weld metal and heat affected zone. Hence, this study shows that, in the absence of a susceptible microstructure, hydrogen assisted cracking is unlikely to occur even if hydrogen level is high. It also confirms that in welding of DMR-249A with indigenously developed E8018 C1 electrode, hydrogen assisted cracking is not a concern and no preheating is required to avoid it during welding.

  9. Aspectos ergonômicos na transferência de pacientes: um estudo realizado com trabalhadores de uma central de transportes de um hospital universitário Aspectos ergonómicos en la transferencia de enfermos: un estudio hecho com trabajadores de una central de transportes de un hospital universitário The transfer of patients and its ergonomic aspects: a study conducted at a university hospital lifting center

    Directory of Open Access Journals (Sweden)

    Cristiane Gonzales Rossi

    2001-09-01

    Full Text Available Com o objetivo de avaliar aspectos ergonômicos na transferência de pacientes com a utilização de maca e cadeira de rodas, observou-se 249 transferências realizadas por trabalhadores da Seção de Escolta de um Hospital Universitário. Os resultados sugerem que a existência dessa equipe é uma iniciativa que deve ser estimulada mas que esses trabalhadores precisam de treinamento específico sobre movimentação e transporte de pacientes e de terem à disposição materiais auxiliares e equipamentos mecânicos.Com el objetivo de avaliar aspectos ergonómicos de transferencia de enfermos com utilización de maca y silla de ruedas, observarán se 249 transferencias realizadas por trabajadores de la Sección de Escolta (Acompañamiento de un Hospital Universitário. Los resultados sugerem que la existencia desse equipo es una iniciativa que debrá ser estimulada. Pero esos trabajadores necessitan entrenamiento especifico sobre mobilizacion y transporte de enfermos e necessitam tener a disposicion materiales auxiliares y equipamentos mecânicos.The purpose of this study was to evaluate ergonomic aspects involved in using a stretcher and a wheel chair to transfer patients. 249 transfers carried out by the workers of a university hospital lifting sector were observed. The observations showed that the idea of having a team to transfer patients has to be stimulated but the members of the team require specific training in handling and transferring patients. Mechanical equipment and other devices should also be available.

  10. Mechanistic and computational studies of the reductive half-reaction of tyrosine to phenylalanine active site variants of D-arginine dehydrogenase.

    Science.gov (United States)

    Gannavaram, Swathi; Sirin, Sarah; Sherman, Woody; Gadda, Giovanni

    2014-10-21

    The flavin-mediated enzymatic oxidation of a CN bond in amino acids can occur through hydride transfer, carbanion, or polar nucleophilic mechanisms. Previous results with D-arginine dehydrogenase from Pseudomonas aeruginosa (PaDADH) using multiple deuterium kinetic isotope effects (KIEs) and computational studies established preferred binding of the substrate protonated on the α-amino group, with cleavages of the NH and CH bonds occurring in asynchronous fashion, consistent with the three possible mechanisms. The hydroxyl groups of Y53 and Y249 are ≤4 Å from the imino and carboxylate groups of the reaction product iminoarginine, suggesting participation in binding and catalysis. In this study, we have investigated the reductive half-reactions of the Y53F and Y249F variants of PaDADH using substrate and solvent deuterium KIEs, solvent viscosity and pH effects, and quantum mechanical/molecular mechanical computational approaches to gain insights into the catalytic roles of the tyrosines and evaluate whether their mutations affect the transition state for substrate oxidation. Both Y53F and Y249F enzymes oxidized D-arginine with steady-state kinetic parameters similar to those of the wild-type enzyme. Rate constants for flavin reduction (k(red)) with D-leucine, a slow substrate amenable to rapid kinetics, were 3-fold smaller than the wild-type value with similar pKa values for an unprotonated group of ∼10.0. Similar pKa values were observed for (app)Kd in the variant and wild-type enzymes. However, cleavage of the substrate NH and CH bonds in the enzyme variants occurred in synchronous fashion, as suggested by multiple deuterium KIEs on k(red). These data can be reconciled with a hydride transfer mechanism, but not with carbanion and polar nucleophilic mechanisms.

  11. Preparation and Characterization of Lithium Zirconium Silicate for CO2 Capture

    Directory of Open Access Journals (Sweden)

    T.S. Bhosale

    2014-10-01

    Full Text Available The samples of lithium zirconium silicate were prepared by precipitation, template and sol-gel meth-ods. The samples were prepared with several mol ratios of Li:Zr:Si. The preparation of lithium zirco-nium silicate samples by precipitation method were carried out by using the lithium nitrate, zirconyl nitrate, zirconium(IV oxypropoxide and tetramethylorthosilicate (TEOS as precursors. The samples of lithium zirconium silicate were prepared by using cetyltrimethyl-ammonium bromide (C-TAB and tetramethyl ammonium hydroxide (TMAOH by template method. The samples of lithium zirconium silicate were characterized by XRD, TEM, SEM, 29Si-MAS NMR and FTIR. The surface area, alkalinity / acidity of the samples of lithium zirconium silicate were measured. The TGA analysis of lithium zirco-nium silicate samples was done. The CO2 captured by the samples of lithium zirconium silicate was es-timated. The captured CO2 by the samples of lithium zirconium silicate was found to be in the range 3.3 to 8.6 wt%. © 2014 BCREC UNDIP. All rights reservedReceived: 27th March 2014; Revised: 31st July 2014; Accepted: 2nd August 2014How to Cite: Bhosale, T.S. , Gaikwad, A.G. (2014. Preparation and Characterization of Lithium Zirconium Silicate for CO2 Capture. Bulletin of Chemical Reaction Engineering & Catalysis, 9(3: 249-262. (doi:10.9767/bcrec.9.3.6646.249-262Permalink/DOI: http://dx.doi.org/10.9767/bcrec.9.3.6646.249-262

  12. Molecular weight–gyration radius relation of globular proteins: a comparison of light scattering, small-angle X-ray scattering and structure-based data

    Science.gov (United States)

    Smilgies, Detlef-M.; Folta-Stogniew, Ewa

    2015-01-01

    The molecular weight–gyration radius relation for a number of globular proteins based on experimental light scattering data is compared with small-angle X-ray scattering data recently published by Mylonas & Svergun [J. Appl. Cryst. (2007 ▸), 40, s245–s249]. In addition, other recent experimental data and theoretical calculations are reviewed. It is found that the M W–R g relation for the globular proteins is well represented by a power law with an exponent of 0.37 (2). PMID:26500468

  13. Structure and tectonics of the southwestern continental margin of India

    Digital Repository Service at National Institute of Oceanography (India)

    Subrahmanyam, V.; Rao, D; Ramana, M.V.; Krishna, K.S.; Murty, G.P.S.; Rao, M.G.

    . 6) were used for interpretation. In addition, these interpretations ,~" E ~p' ;'?" :50 • t N \\[ " /-~ °,,a- ,, I~~ I RVG - IO R'~VG_@. 3d- ," .... RV!-~ ,~','" " ..... " ~,~ ~ RVG - 5 ) .;27m !CORA DIk/H S i~ 2~m ," / / / /,. / /./. 36m... ~'1 \\x \\ i 7"5* -3d -3d -d -56 r'~ ° 3'd A" 3'd so' Fig. 3. Total magnetic intensity anomaly profiles. V. Subrahmanyam et al. / Tectonophysics 249 (1995) 267-282 271 are supplemented by seismic refraction records (Rao, 1976), well-log data...

  14. Domain Modeling: NP_009174.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_009174.1 chr6 Bacteriorhodopsin-like d1h2sa_ chr6/NP_009174.1/NP_009174.1_holo_10-249.pdb swppa 32R,35L,...36G,39P,67L,70L,71L,80M,101Y,114R,115Y,116W,121K,122G,124V,125L,143V,149W,152I,153F,156L,184K,191L,203L,...206V,207L,210V,221A,222F,229G,230L,239L,240R,243R BOG,RET 0 ...

  15. Role of general practitioner in the management of acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Beeleonie Beeleonie

    2005-12-01

    Full Text Available Acute myocardial infarction (AMI has been the leading cause of death in Western countries, as well as in Indonesia. Delay in diagnosis and incorrect early management often result in failure of thrombolytic reperfusion. General practitioner (GP as the primary care, needs to be equipped with the ability to diagnose and moreover to manage AMI. A case of fail thrombolytic management in a 47 years old man after seven hours of angina typical chest pain, after previously managed by GP, is being reported. (Med J Indones 2005; 14:249-52Keywords: acute myocardial infarction, reperfusion, general practitioner

  16. Design of an interactive game-based application for improving the resolution of common Computer Network issues

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    Mario Ciau Uitzil

    2012-11-01

    Full Text Available The need to find new ways to help students in the learning process makes us more involved with technology which evolves every day. This background leads us to find new methods and forms of teaching that help students accelerate their learning skills in a different way from the traditional, as in the case of learning through play, a concept that has been used in many games which have had great impact recently, becoming an innovative tool for learning. This paper shows the design of an interactive game-based application developed with Blender 2.49b tool to be implemented in the area of computer networks.

  17. Naval Law Review, Volume 54, 2007

    Science.gov (United States)

    2007-01-01

    249 Id. §§ 1538(a)(1)(A) – (C). 250 Id. § 1533 (b)(5)(B). 251 Id. § 1537 (b). 252 Smith v. United States, 508 U.S. 223, 228 (1993). 253 Victor v...numbing. Where does it end? The Toledo Blade won a Pulitzer Prize in 2005 for a four part series in October 2004 detailing a summer of murder in...Michael Sallah & Mitch Weiss, Tiger Force, TOLEDO BLADE, Oct. 2004; See also MICHAEL SALLAH & MITCH WEISS, TIGER FORCE (2006). The four part series and

  18. Drug: D03267 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D03267 Drug Gonadorelin diacetate (JP16) C55H75N17O13. (C2H4O2)2 1301.6153 1302.394...fecting individual organs 24 Hormones 249 Miscellaneous 2499 Others D03267 Gonadorelin diacetate (JP16) 7 Ag...gents 7223 Diagnostic reagents for endocrine function D03267 Gonadorelin diacetat...MONES H01CA Gonadotropin-releasing hormones H01CA01 Gonadorelin D03267 Gonadoreli...sturbances V04CM01 Gonadorelin D03267 Gonadorelin diacetate (JP16) Target-based classification of drugs [BR:

  19. Reexamination of the Polymerization of Pyridoxylated Hemoglobin with Glutaraldehyde

    Science.gov (United States)

    1990-01-01

    cross-links was RESULTS AND DISCUSSION assumed to be some form of a Schiff base , a final reduction with NaCNBH:, was attempted. The conditions...hydride-reduced sample to be found in the a-chain cross-links could consist of Schiff bases that could region. conceivably rearrange and/or dissociate. This...involve an a. /3-unsaturated aldehyde 95, 249-255. to form a Schiff base conjugated to a double bond, 14. Gould, S. A., Rosen. A. L., Sehgal. L. It

  20. THE GEOCHEMISTRY AND AGES OF ROCKS IN THE FOOTWALL OF THE BUTULIYN-NUR AND ZAGAN METAMORPHIC CORE COMPLEXES (NORTH MONGOLIA – WESTERN TRANSBAIKALIA)

    OpenAIRE

    T. V. Donskaya; A.M. MAZUKABZOV

    2015-01-01

    This article reviews data on ages of rocks in the footwall of the Butuliyn-Nur and Zagan metamorphic core complexes (MCC) and provides new data on the geochemistry of the rock complexes. It is noted that the oldest rocks are mylonitized gneisses on rhyolites (554 Ma) in the footwall of the Butuliyn-Nur MCC. The Late Permian – Triassic (249–211 Ma) igneous rocks are ubiquitous in the footwall of the Butuliyn-Nur and Zagan MCC. The youngest rocks in the studied MCC are the Jurassic granitoids (...

  1. Impact of Health Care Employees’ Job Satisfaction On Organizational Performance Support Vector Machine Approach

    Directory of Open Access Journals (Sweden)

    Cemil Kuzey

    2012-05-01

    Full Text Available This study was undertaken to search for key factors that contribute to job satisfaction among health care workers, and also to determine the impact of these underlying dimensions of employee satisfaction on organizational performance. Exploratory Factor Analysis (EFA was applied to initially uncover the key factors, and then, in the next stage of analysis, a popular data mining technique, Support Vector Machine (SVM was employed on a sample of 249 to determine the impact of job satisfaction factors on organizational performance. According to the proposed model, the main factors were revealed to be management’s attitude, pay/reward, job security and colleagues.

  2. Superhigh Temperatures and Acoustic Cavitation

    CERN Document Server

    Belyaev, V B; Miller, M B; Sermyagin, A V; Topolnikov, A S

    2003-01-01

    The experimental results on thermonuclear synthesis under acoustic cavitation have been analyzed with the account of the latest data and their discussion. The analysis testifies that this avenue of research is a very promising one. The numerical calculations of the D(d, n)^{3}He reaction rate in the deuterated acetone (C_{3}D_{6}O) under the influence of ultrasound depending on T environment temperature within the range T=249-295 K have been carried out within the framework of hydrodynamic model. The results show that it is possible to improve substantially the effect/background relationship in experiments by decreasing the fluid temperature twenty-thirty degrees below zero.

  3. Temperature Variation of Jiamusi Region in Sanjiang Plain

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    [Objective] The study aimed at analysing the change characteristics of temperature in Jiamusi region of Sanjiang Plain.[Method] Based on temperature data of Jiamusi region in Sanjiang Plain from 1961 to 2010,including Jiamusi,Huanan,Fujin and Fuyuan station,we studied the change trends,abrupt climate change and abnormal years of temperature in Jiamusi region.[Result] Annual average temperature of Jiamusi region in Sanjiang Plain showed increasing trend,with the increase of 0.249-0.412 ℃/10 a.The order of an...

  4. Refuse-derived Fuel Energy Recovery by Plasma Technology

    Directory of Open Access Journals (Sweden)

    Marián LÁZÁR

    2014-06-01

    Full Text Available The paper reports the results of experiments focused upon high temperature gasification of waste with a significant proportion of combustibles. This is refuse-derived fuel (RDF obtained by sorting the combustible components of communal waste. During the gasification of this waste in a plasma reactor (with a waste humidity of circa 24.9 %, when calculated per 1 kg of waste, syngas was obtained in an amount of 1.35 to 1.84 m3∙kg-1. Apart from gas, the gasification process also creates slag of a glassy structure suitable for further use.

  5. The student’s new companion on economic geography

    Directory of Open Access Journals (Sweden)

    Sabine Dörry

    2012-12-01

    Full Text Available To come straight to the point, the new textbook Wirtschaftsgeographie [Economic Geography] by Boris Braun and Christian Schulz is a highly recommendable read. In pursuit of its goal to outline “a very dynamic and multifarious sub-domain of geography” [author’s translation] (p. 249, this book is mainly directed at current and prospective students of the field of economic geography (p. 6. It keeps both these promises in quite an appealing manner. Alongside an insightful introduction to the my...

  6. Laser-Initiated Free Radical Chain Reactions: Synthesis Of Hydroperoxides

    Science.gov (United States)

    Bray, R. G.; Chou, M. S.

    1984-05-01

    We have investigated the advantages of using laser-initiation for the synthesis of cumenehydroperoxide and t-butylhydroperoxide. Laser-initiation significantly improves the oxidation rates of cumene in the liquid phase and iso-butane in the vapor phase (using HBr promoters) with moderate photoefficiencies (418 and 490 respectively). The primary effect of laser-initiation is to reduce the induction period of the reaction. For the oxidation of cumene the beneficial effect of laser initiation is strongly dependent on laser wavelength, alternately enhancing (at 351 nm) or inhibiting (at 249 nm) the oxidation rate. For isobutane oxidation, laser-initiation also minimizes the HBr depletion rate relative to oxidation rate.

  7. Characteristics of Candida isolates from patients with diabetes mellitus.

    OpenAIRE

    Manfredi, M

    2006-01-01

    The present research has investigated the molecular characterization of oral yeasts in healthy individuals from different dental clinical settings in the United Kingdom, and patients from the UK and Italy who were affected by diabetes mellitus (DM) to determine the impact of DM upon candidal infection of the mouth. In the present study of patients with DM from the UK and Italy a lower than expected incidence of oral candidal infections (7/249, 2.8%) was observed. The presence of oral yeasts a...

  8. The Pharmacology of p-Aminopropiophenone in the Detoxification of Cyanide

    Science.gov (United States)

    1992-01-01

    theoretically derived calculations, k , (a rate constant for elimination of PAPP) was found to be 0.0 12 min - ’, k , (a model rate constant) varied...between 0.018 and 0.028 mg/kg/min, although k , ranged from 0.018 to 0.033 min -’. A vcry good fit was obtained by comparing their model to the experimental...Schmiedebergs Arch Exp Pathol Pharmacol I 1964;249:168-75. 48. Guertler AT, Brewer TG, Lagutchik MS, Januszkiewicz AJ, Baskin SI, Martin DG. Effect of

  9. AcEST: BP916201 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 12 OS=Pa... 30 5.6 sp|Q92902|HPS1_HUMAN Hermansky-Pudlak syndrome 1 protein OS=H...omo... 30 7.2 sp|P38793|TRM5_YEAST tRNA (guanine-N(1)-)-methyltransferase OS=S... 30 7.4 sp|Q60HF3|HPS1_MACFA Herman...LTHAFFKAMLFLGAGSVIHAMHH--EQDMRNYGGLRKKIPL 383 >sp|Q92902|HPS1_HUMAN Hermansky-Pudlak syndrome 1 protein OS=H...6 Query: 66 LRTLVTTKQIHRC 28 +LV ++ C Sbjct: 237 SDSLVVEQKESNC 249 >sp|Q60HF3|HPS1_MACFA Hermansky-Pudlak sy

  10. AcEST: BP916318 [AcEST

    Lifescience Database Archive (English)

    Full Text Available p|P38793|TRM5_YEAST tRNA (guanine-N(1)-)-methyltransferase OS=S... 30 5.7 sp|Q92902|HPS1_HUMAN Herman...us musculus GN=Ctnnal1 P... 29 9.8 sp|Q60HF3|HPS1_MACFA Hermansky-Pudlak syndrome 1 protein homolog... 29 9....28 +LV ++ C Sbjct: 237 SDSLVVEQKESNC 249 >sp|Q92902|HPS1_HUMAN Hermansky-Pudlak syndrome 1 protein OS=Homo s...LCHQLQTITKTSLQSKVFLKVDKCITKIRSMMTLVVQLLSL 705 >sp|Q60HF3|HPS1_MACFA Hermansky-Pudlak syndrome 1 protein homo

  11. Avaliação clínica e sistêmica em pacientes que procuram tratamento periodontal = Clinical and systemic evaluation of patients seeking periodontal treatment

    OpenAIRE

    Gusmão, Estela Santos

    2005-01-01

    Com o objetivo de estabelecer as condições clínicas e sistêmicas de pacientes portadores de doença periodontal atendidos na Escola de Aperfeiçoamento Profissional da Associação Brasileira de Odontologia Secção Pernambuco (EAP-ABO/PE) nos anos de 2000-2001, foram levantados 249 prontuários dos quais, 65 foram desconsiderados por falta de preenchimento. Os dados de interesse foram anotados em ficha específica e trabalhados no programa SPSS versão 10. 0. Para análise estatística foram adotadas d...

  12. Transrectal Near-Infrared Optical Tomography for Prostate Imaging

    Science.gov (United States)

    2011-03-01

    2009. CA Cancer J Clin. 2009;59:225-249. 2. Hodge KK, McNeal JE, Stamey TA. Ultrasound guided transrectal core biopsies of the palpably abnormal...near-infrared spectroscopy: pilot results in the breast," Radiology 218, 261-266 (2001). [4] Tara Yates, Jeremy C Hebden, Adam Gibson, Nick ...digital rectal examination as screening tests for prostate carcinoma,” J Am Board Fam Pract.; 16(2):95- 101 (2003). 3. Hodge KK, McNeal JE, Stamey TA

  13. 4-(4-Nitrobenzylpyridine

    Directory of Open Access Journals (Sweden)

    Deeb Taher

    2013-07-01

    Full Text Available The title compound, C12H10N2O2, has a twisted conformation, with a dihedral angle between the planes of the pyridine and benzene rings of 78.4 (2°. The nitro group is coplanar with the attached benzene ring within experimental error. The molecules form centrosymmetric dimers via Car—H...O interactions (H...O = 2.49 Å and the dimers are π-stacked along the b axis [the separation between ring centroids is 3.788 (2 Å].

  14. Development and Characterization of a Mouse Model for Marburg Hemorrhagic Fever

    Science.gov (United States)

    2009-07-01

    Interactions of Marburg virus nucleocapsid proteins. Virology 249:406–417. 5. Bradfute, S. B., K. L. Warfield, and S. Bavari. 2008. Functional CD8 T cell...U. Stroher, L. E. Hensley, A. Grolla, E. A. Fritz, F. Feldmann, H. Feldmann, and S. M. Jones. 2006. Cross-protection against Marburg virus strains by...Valley fever virus . Curr. Mol. Med. 5:827–834. 16. Gedigk, P., H. Bechtelsheimer, and G. Korb. 1968. Pathological anatomy of the “ Marburg virus

  15. Glyburide-Novel Prophylaxis and Effective Treatment for Traumatic Brain Injury

    Science.gov (United States)

    2011-08-01

    flexure of the skull ( Foda and Marmarou, 1994; Marmarou et al., 1994). Our direct measurements of the strain induced in the skull by the blast indicated...consequences of explosives. J. Neurol. Sci. 249, 63–67. Foda , M.A., and Marmarou, A. (1994). A new model of diffuse brain injury in rats. Part II...battlefield injury in the laboratory. J. Neurotrauma 26, 827– 840. Marmarou, A., Foda , M.A., van den Brink, W., Campbell, J., Kita, H., and Demetriadou, K

  16. Active and Passive Control of Supersonic Wakes: Numerical Investigations using DNS and LES

    Science.gov (United States)

    2008-06-01

    traditional RANS is recovered. For the present simulations the FSM was based on the K − ε turbulence model in combination with the explicit algebraic ...approach which is based on suggestion by Durbin [15] for computing fε2. By computing fε2 as fε2 = 1 max [ 1, CT√ ReT ] , (2.13) it is assumed that the...1996. [15] Durbin , P. A., “A Reynolds stress model for near wall turbulence,” J. Fluid Mech., Vol. 249, 1993, pp. 465–498. [16] Sandberg, R. D

  17. 40 CFR 437.46 - Pretreatment standards for existing sources (PSES)

    Science.gov (United States)

    2010-07-01

    ... Cobalt 0.192 0.124 Copper 0.405 0.301 Lead 0.222 0.172 Mercury 0.00234 0.000739 Nickel 3.95 1.45 Silver 0....0962 Chromium 0.947 0.487 Cobalt 0.192 0.124 Copper 0.405 0.301 Lead 0.222 0.172 Mercury 0.00234 0... Antimony 0.249 0.206 Arsenic 0.162 0.104 Cadmium 0.474 0.0962 Chromium 15.5 3.07 Cobalt 0.192 0.124...

  18. On the Distribution of the Zeros of the Riemann Zeta-Function and Existence of Large Gaps

    CERN Document Server

    Saker, S H

    2010-01-01

    In this paper, we prove a new Wirtinger-type inequality and assuming that the Riemann hypothesis is true we establish a new explicit formula for the gaps between the zeros of the Riemann zeta-function. On the hypothesis that the moments of the Hardy Z-function and its derivatives are correctly predicted we establish new lower bounds for the gaps between the zeros. In particular it is proved that consecutive nontrivial zeros often differ by at least 11.249 times the average spacing.

  19. Aflatoxinas: mecanismos de toxicidad en la etiología de cáncer hepático celular

    OpenAIRE

    Urrego Novoa, José R.; Días, Gonzalo J.

    2014-01-01

    La aflatoxina B1 (AFB1), producida por algunoshongos del género Aspergillus, está entrelos más potentes carcinógenos conocidos. Suacción carcinogénica se basa en la biotransformaciónpor el sistema hepático microsomal P450a AFB1-8,9-epóxido, un intermediario altamentereactivo capaz de unirse a las proteínas, a losácidos ribonucleico y desoxirribonucleico; formandoun compuesto estable con el N7 de losresiduos guanil que puede causar mutaciones enel codón 249 del gen p53 supresor de tumores.Esta...

  20. 乙烯精馏塔热泵流程的模拟%Simulation for Heat Pump Flowsheet of Ethylene Tower

    Institute of Scientific and Technical Information of China (English)

    杨德明; 匡华

    2000-01-01

    利用ASPENPLUS软件,对常规乙烯精馏塔的操作工况进行了模拟.在此基础上,提出了该精馏塔的两种开式热泵流程并作了模拟计算,确定了以上两种开式热泵流程的操作条件.计算结果表明,与乙烯常规精馏相比,A型开式热泵流程可节能24.9%,B型开式热泵流程可节能12.6%.