WorldWideScience

Sample records for berkeley um precursor

  1. A geografia histórico-cultural da Escola de Berkeley: um precursor ao surgimento da História Ambiental The Berkeley School's cultural-historical Geography: a precursor to Environmental History's emergence

    Directory of Open Access Journals (Sweden)

    Kent Mathewson

    2008-06-01

    Full Text Available No decorrer das últimas três décadas, a história ambiental se tornou um subcampo reconhecido com seus próprios clássicos, um grande número de monografias notáveis, um fluxo contínuo de artigos publicados e mais do que mil pesquisadores ativos em vários continentes, incluindo uma comunidade crescente na América Latina. Um olhar para além dos limites disciplinares da história mostra que há também outras tradições que se enquadram perfeitamente na temática. A geografia histórico-cultural da Escola de Berkeley sob a égide de Carl Sauer talvez seja uma dessas perspectivas alternativas conhecidas. Muitos estudos de Sauer, seus alunos e colaboradores podem ser considerados pesquisas em história ambiental; muitas delas se baseiam em matérias sobre a América Latina. Neste artigo, procuramos traçar o desenvolvimento dessa corrente alternativa para a história ambiental que se iniciou com a tese de doutoramento de Carl Sauer em 1915 e se consolidou nos anos 50, tendo sua continuidade no presente através dos trabalhos de diversos geógrafos.Over the past three decades environmental history has become a recognized subfield, with a cannon of classics, many dozens of distinguished monographs, a steady flow of published articles, and more than one thousand active practitioners on several continents, including a growing cohort in Latin America. If one looks beyond history's disciplinary bounds, one finds other traditions that equally fit perfectly into the array of environmental history. Perhaps the broadest and deepest current is represented by Carl Sauer's Berkeley School of cultural-historical geography. Much of the work of Sauer, his students, and his associates, can be considered environmental history. Moreover, much of it is based on Latin American materials. In this paper, we trace the development of an alternative current within environmental history - one that began with Carl Sauer's doctoral dissertation in 1915, became well

  2. Bishop Berkeley

    OpenAIRE

    Bindon, Francis (Irish artist, 1690-1765)

    2008-01-01

    'Berkeley was born at his family home, Dysart Castle, near Thomastown, County Kilkenny, Ireland, the eldest son of William Berkeley, a cadet of the noble family of Berkeley. He was educated at Kilkenny College and attended Trinity College, Dublin, completing a Master's degree in 1707. He remained at Trinity College after completion of his degree as a tutor and Greek lecturer.' (en.wikipedia.org)

  3. Environmental research at Berkeley

    CERN Document Server

    1973-01-01

    The information concerning the Energy and Environment Programme at the Lawrence Berkeley Laboratory is based on a talk given at CERN by A.M. Sessler, one of the initiators of the Programme. (Dr. Sessler has been appointed Director of the Lawrence Berkeley Laboratory, in succession to Prof. E. M. McMillan, from 1 November.) Many of the topics mentioned merit an extended story in themselves but the purpose of this article is simply to give a sketch of what is happening.

  4. El idealismo de Berkeley

    Directory of Open Access Journals (Sweden)

    David Sobrevilla

    1995-12-01

    Full Text Available En esta conferencia se examina en qué consiste el idealismo de Berkeley. Para ello se sigue el mismo camino propuesto por G .J. Warnock: se indaga contra qué se opone Berkeley, el materialismo, y cómo lo entiende, y por qué está en contra del mismo. A continuación se reexamina el idealismo berkeleyano, y en la consideración final se juzgan sus virtudes y defectos: algunas de las críticas fundadas que se le han formulado y la visión de la ciencia que se desprende de los escritos de Berkeley. A este respecto se pone en conexión las ideas del autor con algunos planteamientos del último Husserl y con una interpretación de Popper sobre la sorprendente modernidad de algunas de las ideas berkeleyanas sobre la ciencia.

  5. Berkeley mini-collider

    International Nuclear Information System (INIS)

    The Berkeley Mini-Collider, a heavy-ion collider being planned to provide uranium-uranium collisions at T/sub cm/ less than or equal to 4 GeV/nucleon, is described. The central physics to be studied at these energies and our early ideas for a collider detector are presented

  6. Berkeley Low Background Facility

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, K. J.; Norman, E. B. [Department of Nuclear Engineering, University of California-Berkeley, CA 94720 (United States); Nuclear Science Division, Lawrence Berkeley National Laboratory, CA 94720 (United States); Smith, A. R.; Poon, A. W. P.; Chan, Y. D. [Nuclear Science Division, Lawrence Berkeley National Laboratory, CA 94720 (United States); Lesko, K. T. [Physics Division, Lawrence Berkeley National Laboratory, CA 94720 (United States)

    2015-08-17

    The Berkeley Low Background Facility (BLBF) at Lawrence Berkeley National Laboratory (LBNL) in Berkeley, California provides low background gamma spectroscopy services to a wide array of experiments and projects. The analysis of samples takes place within two unique facilities; locally within a carefully-constructed, low background laboratory on the surface at LBNL and at the Sanford Underground Research Facility (SURF) in Lead, SD. These facilities provide a variety of gamma spectroscopy services to low background experiments primarily in the form of passive material screening for primordial radioisotopes (U, Th, K) or common cosmogenic/anthropogenic products; active screening via neutron activation analysis for U,Th, and K as well as a variety of stable isotopes; and neutron flux/beam characterization measurements through the use of monitors. A general overview of the facilities, services, and sensitivities will be presented. Recent activities and upgrades will also be described including an overview of the recently installed counting system at SURF (recently relocated from Oroville, CA in 2014), the installation of a second underground counting station at SURF in 2015, and future plans. The BLBF is open to any users for counting services or collaboration on a wide variety of experiments and projects.

  7. Berkeley Low Background Facility

    International Nuclear Information System (INIS)

    The Berkeley Low Background Facility (BLBF) at Lawrence Berkeley National Laboratory (LBNL) in Berkeley, California provides low background gamma spectroscopy services to a wide array of experiments and projects. The analysis of samples takes place within two unique facilities; locally within a carefully-constructed, low background laboratory on the surface at LBNL and at the Sanford Underground Research Facility (SURF) in Lead, SD. These facilities provide a variety of gamma spectroscopy services to low background experiments primarily in the form of passive material screening for primordial radioisotopes (U, Th, K) or common cosmogenic/anthropogenic products; active screening via neutron activation analysis for U,Th, and K as well as a variety of stable isotopes; and neutron flux/beam characterization measurements through the use of monitors. A general overview of the facilities, services, and sensitivities will be presented. Recent activities and upgrades will also be described including an overview of the recently installed counting system at SURF (recently relocated from Oroville, CA in 2014), the installation of a second underground counting station at SURF in 2015, and future plans. The BLBF is open to any users for counting services or collaboration on a wide variety of experiments and projects

  8. Modelling future changes in climate, ozone-depleting substances and ozone precursor emissions using the whole-atmosphere UM-UKCA model

    Science.gov (United States)

    Banerjee, Antara; Maycock, Amanda; Archibald, Alexander; Telford, Paul; Abraham, Luke; Braesicke, Peter; Pyle, John

    2014-05-01

    Using the recently upgraded whole-atmosphere UM-UKCA chemistry-climate model, we investigate the atmospheric response to future changes in a) greenhouse gases under the RCP4.5 and 8.5 scenarios for climate change, b) ozone-depleting substances (ODS) and a recovery of the ozone layer and c) ozone precursor emissions and tropospheric oxidising capacity. In addition, we combine these scenarios in order to explore the interactions between individual perturbations. Within this framework, the coupled stratosphere-troposphere system and whole-atmosphere chemistry allows us to study the impact of changes in composition of the stratosphere on the troposphere and vice versa. We find that by the year 2100: 1) the stratosphere significantly impacts the troposphere via changes in stratosphere-troposphere exchange (STE) but the chemical changes induced in the troposphere do not impact the stratosphere, 2) perturbations are linearly additive with regard to the total ozone column and tropospheric odd oxygen budget, 3) while the Brewer-Dobson Circulation strengthens under climate change (with an increase in the DJF 70hPa tropical upwards mass flux of ~20% at RCP4.5 and exceeding 30% at RCP8.5), this strengthening is offset by ozone recovery (which on its own leads to a decrease in the mass flux of ~10%) and 4) tropospheric ozone decreases given mitigation of its precursor emissions (with a 10% decrease in ozone burden) but this can be offset by climate change at both RCP4.5 and 8.5 and stratospheric ozone recovery (increasing the burden by 6-13%).

  9. 2009 SCDNR Berkeley County Lidar

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sanborn Map Company completed the original classification of the multiple return LiDAR of Berkeley County, South Carolina in 2009. In 2013, Dewberry was tasked with...

  10. 76 FR 37650 - Safety Zone; 4th of July Festival Berkeley Marina Fireworks Display Berkeley, CA

    Science.gov (United States)

    2011-06-28

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; 4th of July Festival Berkeley Marina... Berkeley Pier, Berkeley, CA in support of the 4th of July Festival Berkeley Marina Fireworks Display... used in the fireworks display. Background and Purpose The City of Berkeley Marina will sponsor the...

  11. 78 FR 29022 - Safety Zone; Fourth of July Fireworks, Berkeley Marina, Berkeley, CA

    Science.gov (United States)

    2013-05-17

    ... SECURITY Coast Guard 33 CFR Part 165 Safety Zone; Fourth of July Fireworks, Berkeley Marina, Berkeley, CA... enforce the safety zone for the Berkeley Marina Fourth of July Fireworks display in the Captain of the...'19'' W (NAD 83) for the Berkeley Marina Fourth of July Fireworks display listed in 33 CFR...

  12. Environmental Survey preliminary report, Lawrence Berkeley Laboratory, Berkeley, California

    Energy Technology Data Exchange (ETDEWEB)

    1988-07-01

    The purpose of this report is to present the preliminary findings made during the Environmental Survey, February 22--29, 1988, at the US Department of Energy (DOE) Lawrence Berkeley Laboratory (LBL) in Berkeley, California. The University of California operates the LBL facility for DOE. The LBL Survey is part of the larger DOE-wide Environmental Survey announced by Secretary John S. Herrington on September 18, 1985. The purpose of this effort is to identify, via no fault'' baseline Surveys, existing environmental problems and areas of environmental risk at DOE facilities, and to rank them on a DOE wide basis. This ranking will enable DOE to more effectively establish priorities for addressing environmental problems and allocate the resources necessary to correct them. Because the Survey is no fault'' and is not an audit,'' it is not designed to identify specific isolated incidents of noncompliance or to analyze environmental management practices. Such incidents and/or management practices will, however, be used in the Survey as a means of identifying existing and potential environmental problems. The LBL Survey was conducted by a multidisciplinary team of technical specialists headed and managed by a Team Leader and Assistant Team Leader from DOE's Office of Environmental Audit. A complete list of the LBL Survey participants and their affiliations is provided in Appendix A. 80 refs., 27 figs., 37 tabs.

  13. Environmental Survey preliminary report, Lawrence Berkeley Laboratory, Berkeley, California

    International Nuclear Information System (INIS)

    The purpose of this report is to present the preliminary findings made during the Environmental Survey, February 22--29, 1988, at the US Department of Energy (DOE) Lawrence Berkeley Laboratory (LBL) in Berkeley, California. The University of California operates the LBL facility for DOE. The LBL Survey is part of the larger DOE-wide Environmental Survey announced by Secretary John S. Herrington on September 18, 1985. The purpose of this effort is to identify, via ''no fault'' baseline Surveys, existing environmental problems and areas of environmental risk at DOE facilities, and to rank them on a DOE wide basis. This ranking will enable DOE to more effectively establish priorities for addressing environmental problems and allocate the resources necessary to correct them. Because the Survey is ''no fault'' and is not an ''audit,'' it is not designed to identify specific isolated incidents of noncompliance or to analyze environmental management practices. Such incidents and/or management practices will, however, be used in the Survey as a means of identifying existing and potential environmental problems. The LBL Survey was conducted by a multidisciplinary team of technical specialists headed and managed by a Team Leader and Assistant Team Leader from DOE's Office of Environmental Audit. A complete list of the LBL Survey participants and their affiliations is provided in Appendix A. 80 refs., 27 figs., 37 tabs

  14. Two amateur astronomers at Berkeley

    CERN Document Server

    Sparavigna, Amelia Carolina

    2012-01-01

    The book on Mechanics of the Physics at Berkeley, by C. Kittel, W.D. Knight and M.A. Ruderman, is proposing at the end of its first chapter some problems of simple astronomy within the solar system. The discussion begins with two amateur astronomers who set for themselves the goal of determining the diameter and mass of the Sun. Here we discuss the problems proposed by the book and some other matters on ancient and modern astronomical studies of the solar system.

  15. 77 FR 37604 - Safety Zone; Fourth of July Fireworks, Berkeley Marina, Berkeley, CA

    Science.gov (United States)

    2012-06-22

    ... SECURITY Coast Guard 33 CFR Part 165 Safety Zone; Fourth of July Fireworks, Berkeley Marina, Berkeley, CA... enforce the safety zone for the Berkeley Marina Fourth of July Fireworks display in the Captain of the... Marina Fourth of July Fireworks display in 33 CFR 165.1191. This safety zone will be in effect from...

  16. Berkeley High-Resolution Ball

    International Nuclear Information System (INIS)

    Criteria for a high-resolution γ-ray system are discussed. Desirable properties are high resolution, good response function, and moderate solid angle so as to achieve not only double- but triple-coincidences with good statistics. The Berkeley High-Resolution Ball involved the first use of bismuth germanate (BGO) for anti-Compton shield for Ge detectors. The resulting compact shield permitted rather close packing of 21 detectors around a target. In addition, a small central BGO ball gives the total γ-ray energy and multiplicity, as well as the angular pattern of the γ rays. The 21-detector array is nearly complete, and the central ball has been designed, but not yet constructed. First results taken with 9 detector modules are shown for the nucleus 156Er. The complex decay scheme indicates a transition from collective rotation (prolate shape) to single- particle states (possibly oblate) near spin 30 h, and has other interesting features

  17. The anticentre old open clusters Berkeley 27, Berkeley 34, and Berkeley 36: new additions to the BOCCE project

    CERN Document Server

    Donati, P; Cignoni, M; Cocozza, G; Tosi, M

    2012-01-01

    In this paper we present the investigation of the evolutionary status of three open clusters: Berkeley 27, Berkeley 34, and Berkeley 36, all located in the Galactic anti-centre direction. All of them were observed with SUSI2@NTT using the Bessel B, V, and I filters. The cluster parameters have been obtained using the synthetic colour-magnitude diagram (CMD) method i.e. the direct comparison of the observational CMDs with a library of synthetic CMDs generated with different evolutionary sets (Padova, FRANEC, and FST). This analysis shows that Berkeley 27 has an age between 1.5 and 1.7 Gyr, a reddening E(B-V) in the range 0.40 and 0.50, and a distance modulus (m-M)_0 between 13.1 and 13.3; Berkeley 34 is older with an age in the range 2.1 and 2.5 Gyr, E(B-V) between 0.57 and 0.64, and (m-M)_0 between 14.1 and 14.3; Berkeley 36, with an age between 7.0 and 7.5 Gyr, has a reddening E(B-V)~0.50 and a distance modulus (m-M)_0 between 13.1 and 13.2. For all the clusters our analysis suggests a sub-solar metallicity ...

  18. The Berkeley Digital Seismic Network

    Science.gov (United States)

    Romanowicz, B.; Dreger, D.; Neuhauser, D.; Karavas, W.; Hellweg, M.; Uhrhammer, R.; Lombard, P.; Friday, J.; Lellinger, R.; Gardner, J.; McKenzie, M. R.; Bresloff, C.

    2007-05-01

    Since it began monitoring earthquakes in northern California 120 years ago, the Berkeley Seismological Laboratory (BSL) has been striving to produce the highest quality and most complete seismic data possible in the most modern way. This goal has influenced choices in instrumentation, installation and telemetry, as well as the investment in expertise and manpower. Since the transition to broadband (BB) instrumentation in the mid- 1980s and to a fully digitally telemetered network in the early 1990s, we have continued these efforts. Each of our 25 BB installations includes three component BB seismometers (STS-1s or STS-2) and digital accelerometers to capture the full range of ground motion from distant teleseisms to large, nearby earthquakes (almost 250 dB). The ground motion is recorded on-site by 24 bit dataloggers. Additional environmental parameters, such as temperature and pressure, are also monitored continuously. Many stations record also C-GPS data that is transmitted continuously to the BSL via shared real-time telemetry. The BDSN's first stations were installed in abandoned mines. In the last 15 years, we developed installations using buried shipping containers to reduce environmental noise and provide security and easy access to the equipment. Data are transmitted in real-time at several sampling rates to one or more processing centers, using frame relay, radio, microwave, and/or satellite. Each site has 7-30 days of onsite data storage to guard against data loss during telemetry outages. Each station is supplied with backup batteries to provide power for 3 days. The BDSN real-time data acquisition, earthquake analysis and archiving computers are housed in a building built to "emergency grade" seismic standards, with air conditioning and power backed up by a UPS and a large generator. Data latency and power are monitored by automated processes that alert staff via pager and email. Data completeness and timing quality are automatically assessed on a daily

  19. Berkeley Lab Laser Accelerator (BELLA) facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Berkeley Lab Laser Accelerator (BELLA) facility (formerly LOASIS) develops advanced accelerators and radiation sources. High gradient (1-100 GV/m) laser-plasma...

  20. The Berkeley TRIGA Mark III research reactor

    International Nuclear Information System (INIS)

    The Berkeley Research Reactor went critical on August 10, 1966, and achieved licensed operating power of 1000 kW shortly thereafter. Since then, the reactor has operated, by and large, trouble free on a one-shift basis. The major use of the reactor is in service irradiations, and many scientific programs are accommodated, both on and off campus. The principal off-campus user is the Lawrence Radiation Laboratory at Berkeley. The reactor is also an important instructional tool in the Nuclear Engineering Department reactor experiments laboratory course, and as a source of radioisotopes for two other laboratory courses given by the Department. Finally, the reactor is used in several research programs conducted within the Department, involving studies with neutron beams and in reactor kinetics

  1. THE YOUNG OPEN CLUSTER BERKELEY 55

    Energy Technology Data Exchange (ETDEWEB)

    Negueruela, Ignacio; Marco, Amparo, E-mail: ignacio.negueruela@ua.es, E-mail: amparo.marco@ua.es [Departamento de Fisica, Ingenieria de Sistemas y Teoria de la Senal, Universidad de Alicante, Apdo. 99, E-03080 Alicante (Spain)

    2012-02-15

    We present UBV photometry of the highly reddened and poorly studied open cluster Berkeley 55, revealing an important population of B-type stars and several evolved stars of high luminosity. Intermediate-resolution far-red spectra of several candidate members confirm the presence of one F-type supergiant and six late supergiants or bright giants. The brightest blue stars are mid-B giants. Spectroscopic and photometric analyses indicate an age 50 {+-} 10 Myr. The cluster is located at a distance d Almost-Equal-To 4 kpc, consistent with other tracers of the Perseus Arm in this direction. Berkeley 55 is thus a moderately young open cluster with a sizable population of candidate red (super)giant members, which can provide valuable information about the evolution of intermediate-mass stars.

  2. Political-social reactor problems at Berkeley

    International Nuclear Information System (INIS)

    For better than ten years there was little public notice of the TRIGA reactor at UC-Berkeley. Then: a) A non-student persuaded the Student and Senate to pass a resolution to request Campus Administration to stop operation of the reactor and remove it from campus. b) Presence of the reactor became a campaign-issue in a City Mayoral election. c) Two local residents reported adverse physical reactions before, during, and after a routine tour of the reactor facility. d) The Berkeley City Council began a study of problems associated with radioactive material within the city. e) Friends Of The Earth formally petitioned the NRC to terminate the reactor's license. Campus personnel have expended many man-hours and many pounds of paper in responding to these happenings. Some of the details are of interest, and may be of use to other reactor facilities. (author)

  3. Lawrence Berkeley Laboratory 1993 Site Environmental Report

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    This annual Site Environmental Report summarizes Lawrence Berkeley Laboratory`s (LBL`s) environmental activities in calendar year (CY) 1993. The purpose of this report is to characterize site environmental management performance, confirm compliance status with environmental standards and requirements, and highlight significant programs and efforts. Its format and content are consistent with the requirements of the US Department of Energy (DOE) Order 5400.1, General Environmental Protection Program.

  4. C. Judson King of UC Berkeley

    Energy Technology Data Exchange (ETDEWEB)

    Prausnitz, John

    2005-06-01

    In the middle of the UC Berkeley campus, next to the Main Library, South Hall is the last surviving building from the original campus, founded about 135 years ago. A tiny tree-shaded appendix to this venerated classical building houses Berkeley's Center for Studies in Higher Education, directed by C. Judson King, former Provost and Senior Vice President--Academic Affairs of the ten-campus University of California and long-time Professor of Chemical Engineering at Berkeley. Jud came to Berkeley in 1963 as assistant professor of chemical engineering, following receipt of a doctor's degree from MIT and a subsequent short appointment as director of the MIT chemical engineering practice school station at what was then Esso (now Exxon) in New Jersey. His undergraduate degree is from Yale. Starting with his MIT doctoral dissertation on gas absorption, Jud has devoted much of his professional career to separation processes. His teaching and research activities have been primarily concerned with separation of mixtures with emphasis on liquid-liquid extraction and drying. As a consultant to Procter and Gamble, he contributed to the technology of making instant coffee. His life-long activities in hiking and camping stimulated Jud's interest in the manufacture of freeze-dried foods (e.g. turkey meat) to minimize the weight of his hiking back-pack. Jud is internationally known not only for his many research publications but even more, for his acclaimed textbook ''Separation Processses'' (McGraw-Hill, second edition 1980) that is used in standard chemical engineering courses in the US and abroad.

  5. Lawrence Berkeley Laboratory 1994 site environmental report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    The 1994 Site Environmental Report summarizes environmental activities at Lawrence Berkeley Laboratory (LBL) for the calendar year (CY) 1994. The report strives to present environmental data in a manner that characterizes the performance and compliance status of the Laboratory`s environmental management programs when measured against regulatory standards and DOE requirements. The report also discusses significant highlight and planning efforts of these programs. The format and content of the report are consistent with the requirements of the U.S. Department of Energy (DOE) Order 5400.1, General Environmental Protection Program.

  6. Lawrence Berkeley Laboratory 1994 site environmental report

    International Nuclear Information System (INIS)

    The 1994 Site Environmental Report summarizes environmental activities at Lawrence Berkeley Laboratory (LBL) for the calendar year (CY) 1994. The report strives to present environmental data in a manner that characterizes the performance and compliance status of the Laboratory's environmental management programs when measured against regulatory standards and DOE requirements. The report also discusses significant highlight and planning efforts of these programs. The format and content of the report are consistent with the requirements of the U.S. Department of Energy (DOE) Order 5400.1, General Environmental Protection Program

  7. Berkeley lab checkpoint/restart (BLCR) for Linux clusters

    Science.gov (United States)

    Hargrove, Paul H.; Duell, Jason C.

    2006-09-01

    This article describes the motivation, design and implementation of Berkeley Lab Checkpoint/Restart (BLCR), a system-level checkpoint/restart implementation for Linux clusters that targets the space of typical High Performance Computing applications, including MPI. Application-level solutions, including both checkpointing and fault-tolerant algorithms, are recognized as more time and space efficient than system-level checkpoints, which cannot make use of any application-specific knowledge. However, system-level checkpointing allows for preemption, making it suitable for responding to ''fault precursors'' (for instance, elevated error rates from ECC memory or network CRCs, or elevated temperature from sensors). Preemption can also increase the efficiency of batch scheduling; for instance reducing idle cycles (by allowing for shutdown without any queue draining period or reallocation of resources to eliminate idle nodes when better fitting jobs are queued), and reducing the average queued time (by limiting large jobs to running during off-peak hours, without the need to limit the length of such jobs). Each of these potential uses makes BLCR a valuable tool for efficient resource management in Linux clusters.

  8. Berkeley lab checkpoint/restart (BLCR) for Linux clusters

    International Nuclear Information System (INIS)

    This article describes the motivation, design and implementation of Berkeley Lab Checkpoint/Restart (BLCR), a system-level checkpoint/restart implementation for Linux clusters that targets the space of typical High Performance Computing applications, including MPI. Application-level solutions, including both checkpointing and fault-tolerant algorithms, are recognized as more time and space efficient than system-level checkpoints, which cannot make use of any application-specific knowledge. However, system-level checkpointing allows for preemption, making it suitable for responding to ''fault precursors'' (for instance, elevated error rates from ECC memory or network CRCs, or elevated temperature from sensors). Preemption can also increase the efficiency of batch scheduling; for instance reducing idle cycles (by allowing for shutdown without any queue draining period or reallocation of resources to eliminate idle nodes when better fitting jobs are queued), and reducing the average queued time (by limiting large jobs to running during off-peak hours, without the need to limit the length of such jobs). Each of these potential uses makes BLCR a valuable tool for efficient resource management in Linux clusters

  9. Three new bricks in the wall: Berkeley 23, Berkeley 31, and King 8

    CERN Document Server

    Cignoni, Michele; Bragaglia, Angela; Tosi, Monica

    2011-01-01

    A comprehensive census of Galactic open cluster properties places unique constraints on the Galactic disc structure and evolution. In this framework we investigate the evolutionary status of three poorly-studied open clusters, Berkeley 31, Berkeley 23 and King 8, all located in the Galactic anti-centre direction. To this aim, we make use of deep LBT observations, reaching more than 6 mag below the main sequence Turn- Off. To determine the cluster parameters, namely age, metallicity, distance, reddening and binary fraction, we compare the observational colour-magnitude diagrams (CMDs) with a library of synthetic CMDs generated with different evolutionary sets (Padova, FRANEC and FST) and metallicities. We find that Berkeley 31 is relatively old, with an age between 2.3 and 2.9 Gyr, and rather high above the Galactic plane, at about 700 pc. Berkeley 23 and King 8 are younger, with best fitting ages in the range 1.1-1.3 Gyr and 0.8-1.3 Gyr, respectively. The position above the Galactic plane is about 500- 600 pc...

  10. Careers in Data Science: A Berkeley Perspective

    Science.gov (United States)

    Koy, K.

    2015-12-01

    Last year, I took on an amazing opportunity to serve as the Executive Director of the new Berkeley Institute for Data Science (BIDS). After a 15-year career working with geospatial data to advance our understanding of the environment, I have been presented with a unique opportunity through BIDS to work with talented researchers from a wide variety of backgrounds. Founded in 2013, BIDS is a central hub of research and education at UC Berkeley designed to facilitate and nurture data-intensive science. We are building a community centered on a cohort of talented data science fellows and senior fellows who are representative of the world-class researchers from across our campus and are leading the data science revolution within their disciplines. Our initiatives are designed to bring together broad constituents of the data science community, including domain experts from the life, social, and physical sciences and methodological experts from computer science, statistics, and applied mathematics. While many of these individuals rarely cross professional paths, BIDS actively seeks new and creative ways to engage and foster collaboration across these different research fields. In this presentation, I will share my own story, along with some insights into how BIDS is supporting the careers of data scientists, including graduate students, postdocs, faculty, and research staff. I will also describe how these individuals we are helping support are working to address a number of data science-related challenges in scientific research.

  11. Berkeley e o papel das hipóteses na filosofia natural Berkeley and the role of hypothesis in natural philosophy

    Directory of Open Access Journals (Sweden)

    Silvio Seno Chibeni

    2010-09-01

    Full Text Available A questão do estatuto epistemológico das hipóteses que postulam entes e mecanismos inobserváveis tornou-se proeminente com o advento da ciência moderna, no século XVII. Uma das razões para isso é que, por um lado, as novas teorias científicas passaram a empregá-las amplamente na explicação dos fenômenos naturais, enquanto que, por outro lado, a epistemologia empirista, geralmente adotada desde então para a análise da ciência, parecia proscrever seu uso. Neste artigo analisam-se as soluções propostas por George Berkeley para essa tensão. Mostra-se que nos Princípios do conhecimento humano ele introduz uma nova noção de explicação científica, segundo a qual a ciência poderia prescindir de hipóteses sobre inobserváveis, quaisquer que sejam. Depois, para acomodar epistemologicamente a mecânica newtoniana, ele propõe, no De motu, a interpretação instrumentalista das hipóteses sobre forças, que são centrais nessa teoria, considerada por ele "a melhor chave para a ciência natural". Finalmente, em sua obra tardia, Siris, Berkeley envolve-se, de forma aparentemente realista, na discussão e defesa de uma série de hipóteses sobre fluidos inobserváveis. Examina-se brevemente, no final do artigo, a possibilidade de conciliar essa posição com os princípios fundamentais da epistemologia e metafísica de Berkeley.The issue of the epistemological status of hypotheses postulating unobservable entities became prominent with the advent of modern science, in the 17th century. The basic reason is that such entities were widely employed by the new scientific theories in the explanation and prediction of natural phenomena, whereas empiricist epistemology, which at that time became very popular among philosophers and scientists, formed a clearly inhospitable background for unobservable elements in general. This paper examines the stands adopted, and the proposals made on this topic by George Berkeley, one of the most important

  12. Lawrence Berkeley Laboratory Affirmative Action Program. Revised

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Lawrence Berkeley Laboratory`s Affirmative Action Program (AAP) serves as a working document that describes current policies, practices, and results in the area of affirmative action. It represents the Laboratory`s framework for an affirmative approach to increasing the representation of people of color and women in segments of our work force where they have been underrepresented and taking action to increase the employment of persons with disabilities and special disabled and Vietnam era veterans. The AAP describes the hierarchy of responsibility for Laboratory affirmative action, the mechanisms that exist for full Laboratory participation in the AAP, the policies and procedures governing recruitment at all levels, the Laboratory`s plan for monitoring, reporting, and evaluating affirmative action progress, and a description of special affirmative action programs and plans the Laboratory has used and will use in its efforts to increase the representation and retention of groups historically underrepresented in our work force.

  13. The Berkeley gas-filled separator

    CERN Document Server

    Ninov, V; McGrath, C A

    1998-01-01

    The BGS is being constructed at the 88-Inch Cyclotron at LBNL in Berkeley. The magnetic configuration of the BGS will allow a large angular acceptance and good suppression of primary beam particles. BGS operates as a mass spectrometer with a A/ Delta A approximately =200 and as a gas filled separator at pressures between 0.1-50 hPa. The reaction products recoiling off a thin target will be collected with efficiencies from 10-80at the focal plane. A Monte Carlo simulation program of the ion transport through the gas-filled magnets in combination of 3-dimensional TOSCA field maps has been developed and reproduces closely the experimental behavior of BGS. (9 refs).

  14. Junior High Schools of Berkeley, California. Bulletin, 1923, No. 4

    Science.gov (United States)

    Preston, James T.; Clark, W. B.; Glessner, H. H.; Hennessey, D. L.

    1923-01-01

    This bulletin demonstrates that Berkeley, California's educational problem is and has been that of meeting the varied needs of a population such as may be found in any typical American city. The varied population needs, together with the rapid growth, have brought many difficult problems to Berkeley, just has they have to other cities. Based on…

  15. Berkeley UPC编译技术分析%Analysis of the Berkeley UPC Compile Technique

    Institute of Scientific and Technical Information of China (English)

    文延华; 黄传信; 漆锋滨

    2004-01-01

    UPC是一种可以在多种体系结构的并行系统上进行移植的基于全局地址空间(GAS)访问的并行编程语言.本文主要介绍了Berkeley UPC编译器的结构特点,分析了它对文本的支持程度和对并行的实现效率.

  16. Thermoset precursor

    International Nuclear Information System (INIS)

    This invention pertains to a distinctive thermoset precursor which is prepared by mixing a resin composition (A) which can be hardened by ionizing radiation, and a resin composition (B) which can be hardened by heat but cannot be hardened by, or is resistant to, ionizing radiation, and by coating or impregnating a molding or other substrate with a sheet or film of this mixture and irradiating this with an ionizing radiation. The principal components of composition (A) and (B) can be the following: (1) an acrylate or methacrylate and an epoxy resin and an epoxy resin hardener; (2) an unsaturated polyester resin and epoxy resin and an epoxy resin hardener; (3) a diacrylate or dimethacrylate or polyethylene glycol and an epoxy resin; (4) an epoxy acrylates or epoxy methacrylate obtained by the addition reaction of epoxy resin and acrylic or methacrylic acid

  17. Radioactive ion beam development in Berkeley

    CERN Document Server

    Wutte, D C; Leitner, M A; Xie, Z Q

    1999-01-01

    Two radioactive ion beam projects are under development at the 88" Cyclotron, BEARS (Berkeley Experiment with accelerated radioactive species) and the 14O experiment. The projects are initially focused on the production of 11C and 14O, but it is planned to expand the program to 17F, 18F, 13N and 76Kr. For the BEARS project, the radioactivity is produced in form of either CO2 or N2O in a small medical 10 MeV proton cyclotron. The activity is then transported through a 300 m long He-jet line to the 88" cyclotron building, injected into the AECR-U ion source and accelerated through the 88" cyclotron to energies between 1 to 30 MeV/ nucleon. The 14O experiment is a new experiment at the 88" cyclotron to measure the energy-shape of the beta decay spectrum. For this purpose, a target transfer line and a radioactive ion beam test stand has been constructed. The radioactivity is produced in form of CO in a hot carbon target with a 20 MeV 3He from the 88" Cyclotron. The activity diffuses through an 8m long stainless s...

  18. Life sciences: Lawrence Berkeley Laboratory, 1988

    Energy Technology Data Exchange (ETDEWEB)

    1989-07-01

    Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program laboratory has emerged, in which the life sciences participate as a full partner. The LBL Human Genome Center is a contribution to the growing international effort to map the human genome. Its achievements represent LBL divisions, including Engineering, Materials and Chemical Sciences, and Information and Computing Sciences, along with Cell and Molecular Biology and Chemical Biodynamics. The Advanced Light Source Life Sciences Center will comprise not only beamlines and experimental end stations, but also supporting laboratories and office space for scientists from across the US. This effort reflects a confluence of scientific disciplines --- this time represented by individuals from the life sciences divisions and by engineers and physicists associated with the Advanced Light Source project. And finally, this report itself, the first summarizing the efforts of all four life sciences divisions, suggests a new spirit of cooperation. 30 figs.

  19. Life sciences: Lawrence Berkeley Laboratory, 1988

    International Nuclear Information System (INIS)

    Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program laboratory has emerged, in which the life sciences participate as a full partner. The LBL Human Genome Center is a contribution to the growing international effort to map the human genome. Its achievements represent LBL divisions, including Engineering, Materials and Chemical Sciences, and Information and Computing Sciences, along with Cell and Molecular Biology and Chemical Biodynamics. The Advanced Light Source Life Sciences Center will comprise not only beamlines and experimental end stations, but also supporting laboratories and office space for scientists from across the US. This effort reflects a confluence of scientific disciplines --- this time represented by individuals from the life sciences divisions and by engineers and physicists associated with the Advanced Light Source project. And finally, this report itself, the first summarizing the efforts of all four life sciences divisions, suggests a new spirit of cooperation. 30 figs

  20. Former Fermilab boss to lead Lawrence Berkeley National Laboratory

    Science.gov (United States)

    Gwynne, Peter

    2016-03-01

    Particle physicist Michael Witherell - current vice-chancellor for research at the University of California, Santa Barbara (UCSB) - has been appointed the next director of the Lawrence Berkeley National Laboratory (LBL).

  1. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1980

    Energy Technology Data Exchange (ETDEWEB)

    Schleimer, G.E. (ed.)

    1981-04-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data on air and water sampling and continuous radiation monitoring for 1980 are presented, and general trends are discussed.

  2. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1980

    International Nuclear Information System (INIS)

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data on air and water sampling and continuous radiation monitoring for 1980 are presented, and general trends are discussed

  3. Annual environmental monitoring report of the Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Schleimer, G.E.; Pauer, R.O. (eds.)

    1990-08-01

    The Lawrence Berkeley Laboratory (LBL) is a multiprogram national laboratory managed by the University of California (UC) for the US Department of Energy (DOE). LBL's major role is to conduct basic and applied science research that is appropriate for an energy research laboratory. The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data for 1989 are presented, and general trends are discussed. 17 refs., 12 figs., 23 tabs.

  4. Dinâmica dos precursores celulares do epitélio olfatório de cães sem raça definida: um estudo imunohistoquímico e ultra-estrutural The dynamic of precursor of the olfactory epithelium of mongrel dogs: an immunohistochemical and ultrastructural study

    Directory of Open Access Journals (Sweden)

    Flávio Ribeiro Alves

    2007-09-01

    Full Text Available O epitélio olfatório apresenta um mecanismo de diferenciação em que células-tronco dão origem a células progenitoras amplificadoras, as quais expressam um gene pró-neural denominado Mammalian Achaete Scute Homolog 1 (Mash1. Estas células podem se diferenciar em receptores olfatórios. O epitélio olfatório de cães sem raça definida (3 machos de um ano e 2 fêmeas de três de idade foi analisado por imunolocalização do antígeno nuclear de proliferação celular (PCNA e por microscopia eletrônica de transmissão. Verificou-se marcação positiva para PCNA em células do epitélio olfatório, particularmente acima da linha da membrana basal. A ultra-estrutura do epitélio olfatório revelou células adjacentes à lâmina basal, cuja eletrodensidade assemelha-se àquelas presentes no epitélio de sustentação, reforçando a idéia da renovação das células de sustentação e dos neurônios olfatórios locais. O epitélio olfatório é composto células basais, comprometidas com sua renovação, caracterizadas através da intensa atividade mitótica, identificada pela reação positiva ao PCNA. Estes resultados sugerem que há reposição das células sustentaculares locais e do sistema através de mecanismos semelhantes.Olfactory epithelium presents a mechanism of differentiation where stem cells give arise to amplifying progenitor cell which express Mammalian Achaete Scute Homolog 1 (Mash1. These cells can be differentiated into olfactory receptors. An immunolocalization study and ultrastructural analysis by transmission electron microscopy of olfactory epithelium of mongrel dogs were made using 3 males (one year old and 2 females (three years old. Labeled cells with positive staining by Proliferating cell nuclear antigen (PCNA were observed in specific areas of the olfactory epithelium, especially above the basal membrane. The ultrastructure revealed cells adjacent to the basal membrane with morphology resembling sustentacular

  5. Pass-Fail Grading at Berkeley: Facts and Opinions.

    Science.gov (United States)

    Suslow, Sidney

    The facts and opinions regarding pass/no pass grading at Berkeley discussed in this report are based on three sources of information. These sources include a survey of faculty conducted in the spring quarter 1970, a survey of undergraduate students in the winter quarter 1971, and the records routinely generated in the Registrar's Office for the…

  6. UC-Berkeley-area citizens decry waste transfer from lab.

    CERN Multimedia

    Nakasato, L

    2002-01-01

    Residents are working to stop the transfer of potentially hazardous and radioactive material from Lawrence Berkeley National Laboratory. The lab has begun to dismantle the Bevatron which has been shut down since 1993 and says eight trucks per day will move material offsite (1 page).

  7. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1986

    Energy Technology Data Exchange (ETDEWEB)

    Schleimer, G.E. (ed.)

    1987-04-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data for 1986 are presented and general trends are discussed. Topics include radiation monitoring, wastewater discharge monitoring, dose distribution estimates, and ground water monitoring. 9 refs., 8 figs., 20 tabs.

  8. Integration Defended: Berkeley Unified's Strategy to Maintain School Diversity

    Science.gov (United States)

    Chavez, Lisa; Frankenberg, Erica

    2009-01-01

    In June 2007, the Supreme Court limited the tools that school districts could use to voluntarily integrate schools. In the aftermath of the decision, educators around the country have sought models of successful plans that would also be legal. One such model may be Berkeley Unified School District's (BUSD) plan. Earlier this year, the California…

  9. Lawrence Berkeley Laboratory Institutional Plan FY 1995--2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    This report presents the details of the mission and strategic plan for Lawrence Berkeley Laboratory during the fiscal years of 1995--2000. It presents summaries of current programs and potential changes; critical success factors such as human resources; management practices; budgetary allowances; and technical and administrative initiatives.

  10. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1986

    International Nuclear Information System (INIS)

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data for 1986 are presented and general trends are discussed. Topics include radiation monitoring, wastewater discharge monitoring, dose distribution estimates, and ground water monitoring. 9 refs., 8 figs., 20 tabs

  11. Hydrogeology and tritium transport in Chicken Creek Canyon,Lawrence Berkeley National Laboratory, Berkeley, California

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, Preston D.; Javandel, Iraj

    2007-10-31

    This study of the hydrogeology of Chicken Creek Canyon wasconducted by the Environmental Restoration Program (ERP) at LawrenceBerkeley National Laboratory (LBNL). This canyon extends downhill fromBuilding 31 at LBNL to Centennial Road below. The leading edge of agroundwater tritium plume at LBNL is located at the top of the canyon.Tritium activities measured in this portion of the plume during thisstudy were approximately 3,000 picocuries/liter (pCi/L), which issignificantly less than the maximum contaminant level (MCL) for drinkingwaterof 20,000 pCi/L established by the Environmental ProtectionAgency.There are three main pathways for tritium migration beyond theLaboratory s boundary: air, surface water and groundwater flow. Thepurpose of this report is to evaluate the groundwater pathway.Hydrogeologic investigation commenced with review of historicalgeotechnical reports including 35 bore logs and 27 test pit/trench logsas well as existing ERP information from 9 bore logs. This was followedby field mapping of bedrock outcrops along Chicken Creek as well asbedrock exposures in road cuts on the north and east walls of the canyon.Water levels and tritium activities from 6 wells were also considered.Electrical-resistivity profiles and cone penetration test (CPT) data werecollected to investigate the extent of an interpreted alluvial sandencountered in one of the wells drilled in this area. Subsequent loggingof 7 additional borings indicated that this sand was actually anunusually well-sorted and typically deeply weathered sandstone of theOrinda Formation. Wells were installed in 6 of the new borings to allowwater level measurement and analysis of groundwater tritium activity. Aslug test and pumping tests were also performed in the wellfield.

  12. Nuclear Medicine at Berkeley Lab: From Pioneering Beginnings to Today (LBNL Summer Lecture Series)

    International Nuclear Information System (INIS)

    Summer Lecture Series 2006: Thomas Budinger, head of Berkeley Lab's Center for Functional Imaging, discusses Berkeley Lab's rich history pioneering the field of nuclear medicine, from radioisotopes to medical imaging.

  13. Calibration of the Berkeley EUV Airglow Rocket Spectrometer

    Science.gov (United States)

    Cotton, Daniel M.; Chakrabarti, Supriya; Siegmund, Oswald

    1989-01-01

    The Berkeley Extreme-ultraviolet Airglow Rocket Spectrometer (BEARS), a multiinstrument sounding rocket payload, made comprehensive measurements of the earth's dayglow. The primary instruments consisted of two near-normal Rowland mount spectrometers: one channel to measure several atomic oxygen features at high spectral resolution (about 1.5 A) in the band passes 980-1040 and 1300-1360 A, and the other to measure EUV dayglow and the solar EUV simultaneously in a much broader bandpass (250-1150 A) at moderate resolution (about 10 A). The payload also included a hydrogen Lyman-alpha photometer to monitor the solar irradiance and goecoronal emissions. The instrument was calibrated at the EUV calibration facility at the University of California at Berkeley, and was subsequently launched successfully on September 30, 1988 aboard a four-stage experimental sounding rocket, Black Brant XII flight 12.041 WT. The calibration procedure and resulting data are presented.

  14. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    International Nuclear Information System (INIS)

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division

  15. Annual site environmental report of the Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Schleimer, G.E.; Pauer, R.O. (eds.)

    1991-05-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory is described. Data for 1990 are presented, and general trends are discussed. The report is organized under the following topics: Environmental Program Overview; Environmental Permits; Environmental Assessments; Environmental Activities; Penetrating Radiation; Airborne Radionuclides; Waterborne Radionuclides; Public Doses Resulting from LBL Operations; Trends -- LBL Environmental Impact; Waterborne Pollutants; Airborne Pollutants; Groundwater Protection; and Quality Assurance. 20 refs., 26 figs., 23 tabs.

  16. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division.

  17. Community Relations Plan for Lawrence Berkeley Laboratory. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    The Lawrence Berkeley Laboratory (LBL) has applied to the California Environmental Protection Agency, Department of Toxic Substances Control (DTSC), for renewal of its Hazardous Waste Handling Facility Permit. A permit is required under Resource Conservation and Recovery Act (RCRA) regulations. The permit will allow LBL to continue using its current hazardous waste handling facility, upgrade the existing facility, and construct a replacement facility. The new facility is scheduled for completion in 1995. The existing facility will be closed under RCRA guidelines by 1996. As part of the permitting process, LBL is required to investigate areas of soil and groundwater contamination at its main site in the Berkeley Hills. The investigations are being conducted by LBL`s Environmental Restoration Program and are overseen by a number of regulatory agencies. The regulatory agencies working with LBL include the California Environmental Protection Agency`s Department of Toxic Substances Control, the California Regional Water Quality Control Board, the Bay Area Air Quality Management District, the East Bay Municipal Utilities District, and the Berkeley Department of Environmental Health. RCRA requires that the public be informed of LBL`s investigations and site cleanup, and that opportunities be available for the public to participate in making decisions about how LBL will address contamination issues. LBL has prepared this Community Relations Plan (CRP) to describe activities that LBL will use to keep the community informed of environmental restoration progress and to provide for an open dialogue with the public on issues of importance. The CRP documents the community`s current concerns about LBL`s Environmental Restoration Program. Interviews conducted between February and April 1993 with elected officials, agency staff, environmental organizations, businesses, site neighbors, and LBL employees form the basis for the information contained in this document.

  18. Lawrence Berkeley National Laboratory 1995 site environmental report

    Energy Technology Data Exchange (ETDEWEB)

    Balgobin, D.; Javandel, I.; Lackner, G.; Smith, C.; Thorson, P.; Tran, H.

    1996-07-01

    The 1995 Site Environmental Report summarizes environmental activities at the Ernest Orlando Lawrence Berkeley National Laboratory (LBNL) for the 1995 calendar year. The report strives to present environmental data in a manner that characterizes the performance and compliance status of the environmental management programs. The report also discusses significant highlights and plans of these programs. Topics discussed include: environmental monitoring, environmental compliance programs, air quality, water quality, ground water protection, sanitary sewer monitoring, soil and sediment quality, vegetation and foodstuffs monitoring, and special studies which include preoperational monitoring of building 85 and 1995 sampling results, radiological dose assessment, and quality assessment.

  19. Assembly Manual for the Berkeley Lab Cosmic Ray Detector

    CERN Document Server

    Collier, M

    2002-01-01

    The Berkeley Lab Cosmic Ray Detector consists of 3 main components that must be prepared separately before they can be assembled. These components are the scintillator, circuit board, and casing. They are described in the main sections of this report, which may be completed in any order. Preparing the scintillator paddles involves several steps--cutting the scintillator material to the appropriate size and shape, preparing and attaching Lucite cookies (optional), polishing the edges, gluing the end to the photomultiplier tube (optional), and wrapping the scintillator. Since the detector has 2 paddles, each of the sections needs to be repeated for the other paddle.

  20. Lawrence Berkeley National Laboratory 1995 site environmental report

    International Nuclear Information System (INIS)

    The 1995 Site Environmental Report summarizes environmental activities at the Ernest Orlando Lawrence Berkeley National Laboratory (LBNL) for the 1995 calendar year. The report strives to present environmental data in a manner that characterizes the performance and compliance status of the environmental management programs. The report also discusses significant highlights and plans of these programs. Topics discussed include: environmental monitoring, environmental compliance programs, air quality, water quality, ground water protection, sanitary sewer monitoring, soil and sediment quality, vegetation and foodstuffs monitoring, and special studies which include preoperational monitoring of building 85 and 1995 sampling results, radiological dose assessment, and quality assessment

  1. Annual environmental monitoring report of the Lawrence Berkeley Laboratory

    International Nuclear Information System (INIS)

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory (LBL) is described. Data for 1988 are presented and general trends are discussed. In order to establish whether LBL research activities produced any impact on the population surrounding the laboratory, a program of environmental air and water sampling and continuous radiation monitoring was carried on throughout the year. For 1988, as in the previous several years, dose equivalents attributable to LBL radiological operations were a small fraction of both the relevant radiation protection guidelines (RPG) and of the natural radiation background. 16 refs., 7 figs., 21 tabs

  2. Assembly Manual for the Berkeley Lab Cosmic Ray Detector

    International Nuclear Information System (INIS)

    The Berkeley Lab Cosmic Ray Detector consists of 3 main components that must be prepared separately before they can be assembled. These components are the scintillator, circuit board, and casing. They are described in the main sections of this report, which may be completed in any order. Preparing the scintillator paddles involves several steps--cutting the scintillator material to the appropriate size and shape, preparing and attaching Lucite cookies (optional), polishing the edges, gluing the end to the photomultiplier tube (optional), and wrapping the scintillator. Since the detector has 2 paddles, each of the sections needs to be repeated for the other paddle

  3. Stability of the Zagreb Carnegie-Mellon-Berkeley model

    CERN Document Server

    Osmanović, H; Švarc, A; Hadžimehmedović, M; Stahov, J

    2011-01-01

    In ref. [1] we have used the Zagreb realization of Carnegie-Melon-Berkeley coupled-channel, unitary model as a tool for extracting pole positions from the world collection of partial wave data, with the aim of eliminating model dependence in pole-search procedures. In order that the method is sensible, we in this paper discuss the stability of the method with respect to the strong variation of different model ingredients. We show that the Zagreb CMB procedure is very stable with strong variation of the model assumptions, and that it can reliably predict the pole positions of the fitted partial wave amplitudes.

  4. Annual environmental monitoring report of the Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Schleimer, G.E. (ed.)

    1989-06-01

    The Environmental Monitoring Program of the Lawrence Berkeley Laboratory (LBL) is described. Data for 1988 are presented and general trends are discussed. In order to establish whether LBL research activities produced any impact on the population surrounding the laboratory, a program of environmental air and water sampling and continuous radiation monitoring was carried on throughout the year. For 1988, as in the previous several years, dose equivalents attributable to LBL radiological operations were a small fraction of both the relevant radiation protection guidelines (RPG) and of the natural radiation background. 16 refs., 7 figs., 21 tabs.

  5. USING DOE-2.1 AT LAWRENCE BERKELEY LABORATORY

    Energy Technology Data Exchange (ETDEWEB)

    Building Energy Analysis Group.; Authors, Various

    1980-09-01

    The purpose of this manual is to assist the DOE-2 user to run DOE-2 and its utility programs at Lawrence Berkeley Laboratory (LBL). It is organized to reflect the facts that every DOE-2 job run at LBL requires certain steps, and that there are options related to DOE-2 job runs available to any DOE-2 user. The standard steps for running a DOE-2 job are as follows: 1. Prepare a job deck 2. Process a job deck 3. Obtain standard output reports.

  6. Assembly Manual for the Berkeley Lab Cosmic Ray Detector

    Energy Technology Data Exchange (ETDEWEB)

    Collier, Michael

    2002-12-17

    The Berkeley Lab Cosmic Ray Detector consists of 3 main components that must be prepared separately before they can be assembled. These components are the scintillator, circuit board, and casing. They are described in the main sections of this report, which may be completed in any order. Preparing the scintillator paddles involves several steps--cutting the scintillator material to the appropriate size and shape, preparing and attaching Lucite cookies (optional), polishing the edges, gluing the end to the photomultiplier tube (optional), and wrapping the scintillator. Since the detector has 2 paddles, each of the sections needs to be repeated for the other paddle.

  7. Lipoprotein subclasses in genetic studies: The Berkeley Data Set

    Energy Technology Data Exchange (ETDEWEB)

    Krauss, R.M.; Williams, P.T.; Blanche, P.J.; Cavanaugh, A.; Holl, L.G. [Lawrence Berkeley Lab., CA (United States); Austin, M.A. [Washington Univ., Seattle, WA (United States). Dept. of Epidemiology

    1992-10-01

    Data from the Berkeley Data Set was used to investigate familial correlations of HDL-subclasses. Analysis of the sibling intraclass correlation coefficient by HDL particle diameter showed that sibling HDL levels were significantly correlated for HDL{sub 2b}, HDL{sub 3a} and HDL{sub 3b} subclasses. The percentage of the offsprings` variance explained by their two parents. Our finding that parents and offspring-have the highest correlation for HDL{sub 2b} is consistent with published reports that show higher heritability estimates for HDL{sub 2} compared with HDL{sub 3}{minus} cholesterol.

  8. Earthquakes: hydrogeochemical precursors

    Science.gov (United States)

    Ingebritsen, Steven E.; Manga, Michael

    2014-01-01

    Earthquake prediction is a long-sought goal. Changes in groundwater chemistry before earthquakes in Iceland highlight a potential hydrogeochemical precursor, but such signals must be evaluated in the context of long-term, multiparametric data sets.

  9. Berkeley extreme-ultraviolet airglow rocket spectrometer: BEARS.

    Science.gov (United States)

    Cotton, D M; Chakrabarti, S

    1992-09-20

    We describe the Berkeley extreme-UV airglow rocket spectrometer, which is a payload designed to test several thermospheric remote-sensing concepts by measuring the terrestrial O I far-UV and extreme-UV dayglow and the solar extreme-UV spectrum simultaneously. The instrument consisted of two near-normal Rowland mount spectrometers and a Lyman-alpha photometer. The dayglow spectrometer covered two spectral regions from 980 to 1040 A and from 1300 to 1360 A with 1.5-A resolution. The solar spectrometer had a bandpass of 250-1150 A with an ~ 10-A resolution. All three spectra were accumulated by using a icrochannel-plate-intensified, two-dimensional imaging detector with three separate wedge-and strip anode readouts. The hydrogen Lyman-alpha photometer was included to monitor the solar Lyman-alpha irradiance and geocoronal Lyman-alpha emissions. The instrument was designed, fabricated, and calibrated at the University of California, Berkeley and was successfully launched on 30 September 1988 aboard the first test flight of a four-stage sounding rocket, Black Brant XII. PMID:20733778

  10. Lawrence Berkeley National Laboratory 1997 Site Environmental Report Vol. I

    International Nuclear Information System (INIS)

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of U.S. Department of Energy Order 231.1. The Site Environmental Report for 1997 is intended to summarize Berkeley Lab's compliance with environmental standards and requirements, characterize environmental management efforts through surveillance and monitoring activities, and highlight significant programs and efforts for calendar year 1997. This report is structured into three basic areas that cover a general overview of the Laboratory, the status of environmental programs, and the results of the surveillance and monitoring activities, including air quality, surface water, groundwater, sanitary sewer, soil and sediment, vegetation and foodstuffs, radiation dose assessment, and quality assurance. The report is separated into two volumes. Volume I contains the body of the report, a list of references, a list of acronyms and abbreviations, a glossary, Appendix A (NESHAPS annual report), and Appendix B (distribution list for volume I). Volume II contains Appendix C, the individual data results from monitoring programs. Each chapter in volume I begins with an outline of the sections that follow

  11. Seismic Protection of Laboratory Contents: The UC Berkeley Science Building Case Study

    OpenAIRE

    Comerio, Mary C.

    2003-01-01

    The research described in this report is a part of the Disaster Resistant University (DRU) initiative funded by the Federal Emergency Management Agency (FEMA) and the University of California, Berkeley. The first phase of the Disaster Resistant University initiative produced a study of potential earthquake losses at UC Berkeley together with an analysis of the economic impacts. In that report, Comerio (2000) found that despite the extraordinary building retrofit program, the UC Berkeley cam...

  12. Identification of Desirable Precursor Properties for Solution Precursor Plasma Spray

    Science.gov (United States)

    Muoto, Chigozie K.; Jordan, Eric H.; Gell, Maurice; Aindow, Mark

    2011-06-01

    In solution precursor plasma spray chemical precursor solutions are injected into a standard plasma torch and the final material is formed and deposited in a single step. This process has several attractive features, including the ability to rapidly explore new compositions and to form amorphous and metastable phases from molecularly mixed precursors. Challenges include: (a) moderate deposition rates due to the need to evaporate the precursor solvent, (b) dealing on a case by case basis with precursor characteristics that influence the spray process (viscosity, endothermic and exothermic reactions, the sequence of physical states through which the precursor passes before attaining the final state, etc.). Desirable precursor properties were identified by comparing an effective precursor for yttria-stabilized zirconia with four less effective candidate precursors for MgO:Y2O3. The critical parameters identified were a lack of major endothermic events during precursor decomposition and highly dense resultant particles.

  13. Early History of Heavy Isotope Research at Berkeley

    Energy Technology Data Exchange (ETDEWEB)

    Glenn T. Seaborg

    1976-06-01

    I have had the idea for some time that it would be interesting and worthwhile to put together an account of the early work on heavy isotopes at Berkeley. Of a special interest is the discovery of plutonium (atomic number 94) and the isotope U{sup 233}, and the demonstration of their fission with slow neutrons. This work served as a prelude to the subsequent Plutonium Project (Metallurgical Project) centered at the University of Chicago, in connection with which I have also had the idea of putting together a history of the work of my chemistry group. I have decided that it would be an interesting challenge to write this account on a day-to-day basis in a style that would be consistent with the entries having been written at the end of each day. The aim would be to make this history as accurate as possible by going back to the original records and using them with meticulous care.

  14. BVI photometry of the very old open cluster Berkeley 17

    CERN Document Server

    Bragaglia, A; Marconi, G; Tosi, M; Andreuzzi, Gloria; Bragaglia, Angela; Marconi, Gianni; Tosi, Monica

    2006-01-01

    We have obtained BVI CCD imaging of Berkeley 17, an anticentre open cluster that competes with NGC 6791 as the oldest known open cluster. Using the synthetic colour magnitude diagrams (CMD) technique with three sets of evolutionary tracks we have determined that its age is 8.5 - 9.0 Gyr, it distance modulus is (m-M)_0 = 12.2, with a reddening of E(B-V) = 0.62 - 0.60. Differential reddening, if present, is at the 5 % level. All these values have been obtained using models with metallicity about half of solar (Z=0.008 or Z=0.01 depending on the stellar evolution tracks), which allows us to reproduce the features of the cluster CMD better than other metallicities. Finally, from the analysis of a nearby comparison field we think to have intercepted a portion of the disrupting Canis Major dwarf galaxy.

  15. Berkeley Program Offers New Option for Financing Residential PV Systems

    Energy Technology Data Exchange (ETDEWEB)

    Bolinger, Mark A

    2008-07-06

    Readily accessible credit has often been cited as a necessary ingredient to open up the market for residential photovoltaic (PV) systems. Though financing does not reduce the high up-front cost of PV, by spreading that cost over some portion of the system's life, financing can certainly make PV systems more affordable. As a result, a number of states have, in the past, set up special residential loan programs targeting the installation of renewable energy systems and/or energy-efficiency improvements and often featuring low interest rates, longer terms and no-hassle application requirements. Historically, these loan programs have had mixed success (particularly for PV), for a variety of reasons, including a historical lack of homeowner interest in PV, a lack of program awareness, a reduced appeal in a low-interest-rate environment, and a tendency for early PV adopters to be wealthy and not in need of financing. Some of these barriers have begun to fade. Most notably, homeowner interest in PV has grown in some states, particularly those that offer solar rebates. The passage of the Energy Policy Act of 2005 (EPAct 2005), however, introduced one additional roadblock to the success of low-interest PV loan programs: a residential solar investment tax credit (ITC), subject to the Federal government's 'anti-double-dipping' rules. Specifically, the residential solar ITC--equal to 30% of the system's tax basis, capped at $2000--will be reduced or offset if the system also benefits from what is known as 'subsidized energy financing', which is likely to include most government-sponsored low-interest loan programs. Within this context, it has been interesting to note the recent flurry of announcements from a number of U.S cities concerning a new type of PV financing program. Led by the city of Berkeley, Calif., these cities propose to offer their residents the ability to finance the installation of a PV system using increased property tax

  16. Tiger Team assessment of the Lawrence Berkeley Laboratory, Washington, DC

    Energy Technology Data Exchange (ETDEWEB)

    1991-02-01

    This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment of the Lawrence Berkeley Laboratory (LBL) conducted from January 14 through February 15, 1991. The purpose of the assessment was to provide the Secretary of Energy with the status of environment, safety, and health (ES H) programs at LBL. The Tiger Team concluded that curtailment of cessation of any operations at LBL is not warranted. However, the number and breadth of findings and concerns from this assessment reflect a serious condition at this site. In spite of its late start, LBL has recently made progress in increasing ES H awareness at all staff levels and in identifying ES H deficiencies. Corrective action plans are inadequate, however, many compensatory actions are underway. Also, LBL does not have the technical expertise or training programs nor the tracking and followup to effectively direct and control sitewide guidance and oversight by DOE of ES H activities at LBL. As a result of these deficiencies, the Tiger Team has reservations about LBL's ability to implement effective actions in a timely manner and, thereby, achieve excellence in their ES H program. 4 figs., 24 tabs.

  17. Status of the UC-Berkeley SETI Efforts

    CERN Document Server

    Korpela, Eric J; Bankay, Robert; Cobb, Jeff; Howard, Andrew; Lebofsky, Matt; Siemion, Andrew P V; von Korff, Joshua; Werthimer, Dan

    2011-01-01

    We summarize radio and optical SETI programs based at the University of California, Berkeley. The SEVENDIP optical pulse search looks for ns time scale pulses at visible wavelengths using an automated 30 inch telescope. The ongoing SERENDIP V.v sky survey searches for radio signals at the 300 meter Arecibo Observatory. The currently installed configuration supports 128 million channels over a 200 MHz bandwidth with ~1.6 Hz spectral resolution. SETI@home uses the desktop computers of volunteers to analyze over 160 TB of data at taken at Arecibo looking for two types of continuous wave signals and two types of pulsed signals. A version to be released this summer adds autocorrelation analysis to look for complex wave forms that have been repeated (and overlayed) after a short delay. SETI@home will soon be processing data of Kepler exoplanet systems collected at the GBT. The Astropulse project is the first SETI search for $\\mu$s time scale dispersed pulses in the radio spectrum. We recently reobserved 114 sky loc...

  18. Tiger Team assessment of the Lawrence Berkeley Laboratory, Washington, DC

    International Nuclear Information System (INIS)

    This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment of the Lawrence Berkeley Laboratory (LBL) conducted from January 14 through February 15, 1991. The purpose of the assessment was to provide the Secretary of Energy with the status of environment, safety, and health (ES ampersand H) programs at LBL. The Tiger Team concluded that curtailment of cessation of any operations at LBL is not warranted. However, the number and breadth of findings and concerns from this assessment reflect a serious condition at this site. In spite of its late start, LBL has recently made progress in increasing ES ampersand H awareness at all staff levels and in identifying ES ampersand H deficiencies. Corrective action plans are inadequate, however, many compensatory actions are underway. Also, LBL does not have the technical expertise or training programs nor the tracking and followup to effectively direct and control sitewide guidance and oversight by DOE of ES ampersand H activities at LBL. As a result of these deficiencies, the Tiger Team has reservations about LBL's ability to implement effective actions in a timely manner and, thereby, achieve excellence in their ES ampersand H program. 4 figs., 24 tabs

  19. Annual environmental monitoring report of the Lawrence Berkeley Laboratory, 1977

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, L.D. (ed.)

    1978-03-01

    The data obtained from the Environmental Monitoring Program of the Lawrence Berkeley Laboratory for the Calendar year 1977 are described and general trends are discussed. The general trend of decreasing radiation levels at our site boundary due to accelerator operation during past years has leveled off during 1977 and in some areas shows a slight but not statistically significant increase as predicted in last year's summary. There were changes in both ion beams as well as current which have resulted in shifts in maxima at the monitoring stations. The gamma levels are once again reported as zero. There is only one period of detectable gamma radiation due to accelerator operation. The annual dose equivalent are reported from the environmental monitoring stations since they have been established. Radiation levels at the Olympus Gate Station have shown a steady decline since 1959 when estimates were first made. The Olympus Gate Station is in direct view of the Bevatron and most directly influenced by that accelerator. Over the past several years the atmospheric sampling program has, with the exception of occasional known releases, yielded data which are within the range of normal background. The surface water program always yields results within the range of normal background. As no substantial changes in the quantities of radionuclides used are anticipated, no changes are expected in these observations.

  20. A study of the old galactic star cluster Berkeley 32

    CERN Document Server

    Richtler, T; Richtler, Tom; Sagar, Ram

    2001-01-01

    We present new CCD photometry of the distant old open star cluster Berkeley 32 in Johnson V and Cousins I passbands. A total of about 3200 stars have been observed in a field of 13X13 arcmin**2. The colour-magnitude diagram in V, (V-I) has been generated down to V = 22 mag. A broad but well defined main sequence is clearly visible. Some blue stragglers, a well developed subgiant branch and a Red Clump are also seen. By fitting isochrones to this CMD as well as to other CMDs available in the literature, and using the Red Clump location, the reddening, distance and age of the star cluster have been determined. The cluster has a distance of 3.3 kpc, its radius is about 2.4 pc; the reddening E(B-V) is 0.08 mag and the age is 6.3 Gyr. By comparison with theoretical isochrones, a metallicity of [Fe/H]= -0.2 dex has been estimated. We find a much flatter mass function than what has been found for young clusters. If the mass function is a power law dN/dm = const.*m**alpha, then we get alpha = -0.5+-0.3 in the mass ra...

  1. The EM Earthquake Precursor

    Science.gov (United States)

    Jones, K. B., II; Saxton, P. T.

    2013-12-01

    Many attempts have been made to determine a sound forecasting method regarding earthquakes and warn the public in turn. Presently, the animal kingdom leads the precursor list alluding to a transmission related source. By applying the animal-based model to an electromagnetic (EM) wave model, various hypotheses were formed, but the most interesting one required the use of a magnetometer with a differing design and geometry. To date, numerous, high-end magnetometers have been in use in close proximity to fault zones for potential earthquake forecasting; however, something is still amiss. The problem still resides with what exactly is forecastable and the investigating direction of EM. After the 1989 Loma Prieta Earthquake, American earthquake investigators predetermined magnetometer use and a minimum earthquake magnitude necessary for EM detection. This action was set in motion, due to the extensive damage incurred and public outrage concerning earthquake forecasting; however, the magnetometers employed, grounded or buried, are completely subject to static and electric fields and have yet to correlate to an identifiable precursor. Secondly, there is neither a networked array for finding any epicentral locations, nor have there been any attempts to find even one. This methodology needs dismissal, because it is overly complicated, subject to continuous change, and provides no response time. As for the minimum magnitude threshold, which was set at M5, this is simply higher than what modern technological advances have gained. Detection can now be achieved at approximately M1, which greatly improves forecasting chances. A propagating precursor has now been detected in both the field and laboratory. Field antenna testing conducted outside the NE Texas town of Timpson in February, 2013, detected three strong EM sources along with numerous weaker signals. The antenna had mobility, and observations were noted for recurrence, duration, and frequency response. Next, two

  2. um estudo de caso

    OpenAIRE

    Costa, Cátia Filipa Pereira da

    2011-01-01

    Dissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Psicologia Jurídica As situações de abuso sexual de crianças nas quais o perpetrador pertence ao sexo feminino obtiveram ao longo dos últimos anos um acrescido reconhecimento por parte da comunidade científica, evidenciado pelo significativo incremento das investigações no âmbito desta temática consistindo na sua maioria estudos de caso. Um conjunto de particularidades encont...

  3. Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

    Energy Technology Data Exchange (ETDEWEB)

    1992-10-01

    The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation's scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory's ongoing research programs. The plan is an institutional management report for integration with the Department of Energy's strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy's program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory's scientific and support divisions.

  4. Lawrence Berkeley Laboratory, Institutional Plan FY 1994--1999

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. For FY 1994-1999 the Institutional Plan reflects significant revisions based on the Laboratory`s strategic planning process. The Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory, and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff diversity and development program. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The new section on Information Resources reflects the importance of computing and communication resources to the Laboratory. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process.

  5. Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

    Energy Technology Data Exchange (ETDEWEB)

    Chew, Joseph T.; Stroh, Suzanne C.; Maio, Linda R.; Olson, Karl R.; Grether, Donald F.; Clary, Mary M.; Smith, Brian M.; Stevens, David F.; Ross, Loren; Alper, Mark D.; Dairiki, Janis M.; Fong, Pauline L.; Bartholomew, James C.

    1992-10-01

    The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The plan is an institutional management report for integration with the Department of Energy`s strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory`s scientific and support divisions.

  6. Lawrence Berkeley Laboratory Institutional Plan FY 1987-1992

    Energy Technology Data Exchange (ETDEWEB)

    Various

    1986-12-01

    The Lawrence Berkeley Laboratory, operated by the University of California for the Department of Energy, provides national scientific leadership and supports technological innovation through its mission to: (1) Perform leading multidisciplinary research in general sciences and energy sciences; (2) Develop and operate unique national experimental facilities for use by qualified investigators; (3) Educate and train future generations of scientists and engineers; and (4) Foster productive relationships between LBL research programs and industry. The following areas of research excellence implement this mission and provide current focus for achieving DOE goals. GENERAL SCIENCES--(1) Accelerator and Fusion Research--accelerator design and operation, advanced accelerator technology development, accelerator and ion source research for heavy-ion fusion and magnetic fusion, and x-ray optics; (2) Nuclear Science--relativistic heavy-ion physics, medium- and low-energy nuclear physics, nuclear theory, nuclear astrophysics, nuclear chemistry, transuranium elements studies, nuclear data evaluation, and detector development; (3) Physics--experimental and theoretical particle physics, detector development, astrophysics, and applied mathematics. ENERGY SCIENCES--(1) Applied Science--building energy efficiency, solar for building systems, fossil energy conversion, energy storage, and atmospheric effects of combustion; (2) Biology and Medicine--molecular and cellular biology, diagnostic imaging, radiation biophysics, therapy and radiosurgery, mutagenesis and carcinogenesis, lipoproteins, cardiovascular disease, and hemopoiesis research; (3) Center for Advanced Materials--catalysts, electronic materials, ceramic and metal interfaces, polymer research, instrumentation, and metallic alloys; (4) Chemical Biodynamics--molecular biology of nucleic acids and proteins, genetics of photosynthesis, and photochemistry; (5) Earth Sciences--continental lithosphere properties, structures and

  7. Reverse tracing of precursors and earthquake precursors in Taiwan

    Institute of Scientific and Technical Information of China (English)

    WANG Li-ping; LI Yong; MA Li; ZHANG Shu-mei

    2008-01-01

    In this paper, we investigate the precursors of large earthquakes in the eastern region of Taiwan by means of the reverse tracing of precursors. We discuss the parameters which are suitable for the seismic chains and intermedi-ate-term patterns in this region and obtain the threshold of the patterns. Applying the linear discriminate method to the intermediate-term patterns of seismic chains, we present an approach for exploring the precursors of large earthquakes. The results show that this method can reduce the false alarm rate for large earthquakes in this region, and the reverse tracing of precursors can be applied to the eastern region of Taiwan.

  8. Precursor flares in OJ 287

    OpenAIRE

    Pihajoki, P.; Valtonen, M.; Zola, S.; Liakos, A.; Drozdz, M.; Winiarski, M.; Ogloza, W.; Koziel-Wierzbowska, D.; Provencal, J.; Nilsson, K.; Berdyugin, A.; Lindfors, E.; Reinthal, R.; Sillanpää, A.; Takalo, L.

    2012-01-01

    We have studied three most recent precursor flares in the light curve of the blazar OJ 287 while invoking the presence of a precessing binary black hole in the system to explain the nature of these flares. Precursor flare timings from the historical light curves are compared with theoretical predictions from our model that incorporate effects of an accretion disk and post-Newtonian description for the binary black hole orbit. We find that the precursor flares coincide with the secondary black...

  9. Generation of Nonlinear Vortex Precursors

    Science.gov (United States)

    Chen, Yue-Yue; Feng, Xun-Li; Liu, Chengpu

    2016-07-01

    We numerically study the propagation of a few-cycle pulse carrying orbital angular momentum (OAM) through a dense atomic system. Nonlinear precursors consisting of high-order vortex harmonics are generated in the transmitted field due to carrier effects associated with ultrafast Bloch oscillation. The nonlinear precursors survive to propagation effects and are well separated with the main pulse, which provides a straightforward way to measure precursors. By virtue of carrying high-order OAM, the obtained vortex precursors as information carriers have potential applications in optical information and communication fields where controllable loss, large information-carrying capacity, and high speed communication are required.

  10. Generation of nonlinear vortex precursors

    CERN Document Server

    Chen, Yue-Yue; Liu, Chengpu

    2016-01-01

    We numerically study the propagation of a few-cycle pulse carrying orbital angular momentum (OAM) through a dense atomic system. Nonlinear precursors consisting of high-order vortex har- monics are generated in the transmitted field due to ultrafast Bloch oscillation. The nonlinear precursors survive to propagation effects and are well separated with the main pulse, which provide a straightforward way of measuring precursors. By the virtue of carrying high-order OAM, the obtained vortex precursors as information carriers have potential applications in optical informa- tion and communication fields where controllable loss, large information-carrying capacity and high speed communication are required.

  11. PRECURSOR FLARES IN OJ 287

    Energy Technology Data Exchange (ETDEWEB)

    Pihajoki, P.; Berdyugin, A.; Lindfors, E.; Reinthal, R.; Sillanpaeae, A.; Takalo, L. [Tuorla Observatory, Department of Physics and Astronomy, University of Turku, FI-21500 Piikkioe (Finland); Valtonen, M.; Nilsson, K. [Finnish Centre for Astronomy with ESO, University of Turku, FI-21500 Piikkioe (Finland); Zola, S.; Koziel-Wierzbowska, D. [Astronomical Observatory, Jagiellonian University, ul. Orla 171, PL-30-244 Krakow (Poland); Liakos, A. [Department of Astrophysics, Astronomy and Mechanics, University of Athens, GR 157 84 Zografos, Athens, Hellas (Greece); Drozdz, M.; Winiarski, M.; Ogloza, W. [Mount Suhora Observatory, Pedagogical University, ul. Podchorazych 2, PL-30-084 Krakow (Poland); Provencal, J. [Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States); Santangelo, M. M. M. [O.A.C. Osservatorio Astronomico di Capannori, Via di Valle, I-55060 Vorno, Capannori (Italy); Salo, H. [Department of Physical Sciences, University of Oulu, P.O. Box 3000, FI-90014 University of Oulu (Finland); Chandra, S.; Ganesh, S.; Baliyan, K. S., E-mail: popiha@utu.fi [Astronomy and Astrophysics Division, Physical Research Laboratory, Ahmedabad 380009 (India); and others

    2013-02-10

    We have studied three most recent precursor flares in the light curve of the blazar OJ 287 while invoking the presence of a precessing binary black hole in the system to explain the nature of these flares. Precursor flare timings from the historical light curves are compared with theoretical predictions from our model that incorporate effects of an accretion disk and post-Newtonian description for the binary black hole orbit. We find that the precursor flares coincide with the secondary black hole descending toward the accretion disk of the primary black hole from the observed side, with a mean z-component of approximately z{sub c} = 4000 AU. We use this model of precursor flares to predict that precursor flare of similar nature should happen around 2020.96 before the next major outburst in 2022.

  12. A community of scientists: cultivating scientific identity among undergraduates within the Berkeley Compass Project

    Science.gov (United States)

    Aceves, Ana V.; Berkeley Compass Project

    2015-01-01

    The Berkeley Compass Project is a self-formed group of graduate and undergraduate students in the physical sciences at UC Berkeley. Our goals are to improve undergraduate physics education, provide opportunities for professional development, and increase retention of students from populations typically underrepresented in the physical sciences. For students who enter as freshmen, the core Compass experience consists of a summer program and several seminar courses. These programs are designed to foster a diverse, collaborative student community in which students engage in authentic research practices and regular self-reflection. Compass encourages undergraduates to develop an identity as a scientist from the beginning of their university experience.

  13. The Indirect Perception of Distance: Interpretive Complexities in Berkeley's Theory of Vision

    Directory of Open Access Journals (Sweden)

    Michael James Braund

    2007-12-01

    Full Text Available The problem of whether perception is direct or if it depends on additional, cognitive contributions made by the perceiving subject, is posed with particular force in an Essay towards a New Theory of Vision (NTV. It is evident from the recurrent treatment it receives therein that Berkeley considers it to be one of the central issues concerning perception. Fittingly, the NTV devotes the most attention to it. In this essay, I deal exclusively with Berkeley's treatment of the problem of indirect distance perception, as it is presented in the context of that work.

  14. 77 FR 75448 - Welded Tube-Berkeley Including On-Site Leased Workers From Snelling, Aerotek and Express...

    Science.gov (United States)

    2012-12-20

    ... Employment and Training Administration Welded Tube--Berkeley Including On-Site Leased Workers From Snelling... Worker Adjustment Assistance on October 10, 2012, applicable to workers of Welded Tube--Berkeley... Register on October 29, 2012 (77 FR 65583). At the request of South Carolina State, the Department...

  15. Searching the "Nuclear Science Abstracts" Data Base by Use of the Berkeley Mass Storage System

    Science.gov (United States)

    Herr, J. Joanne; Smith, Gloria L.

    1972-01-01

    Advantages of the Berkeley Mass Storage System (MSS) for information retrieval other than its size are: high serial-read rate, archival data storage; and random-access capability. By use of this device, the search cost in an SDI system based on the Nuclear Science Abstracts" data base was reduced by 20 percent. (6 references) (Author/NH)

  16. The Berkeley Puppet Interview: A Screening Instrument for Measuring Psychopathology in Young Children

    Science.gov (United States)

    Stone, Lisanne L.; van Daal, Carlijn; van der Maten, Marloes; Engels, Rutger C. M. E.; Janssens, Jan M. A. M.; Otten, Roy

    2014-01-01

    Background: While child self-reports of psychopathology are increasingly accepted, little standardized instruments are utilized for these practices. The Berkeley Puppet Interview (BPI) is an age-appropriate instrument for self-reports of problem behavior by young children. Objective: Psychometric properties of the Dutch version of the BPI will be…

  17. The principle of phase stability and the accelerator program at Berkeley, 1945--1954

    International Nuclear Information System (INIS)

    The discovery of the Principle of Phase Stability by Vladimir Veksler and Edwin McMillian and the end of the war released a surge of accelerator activity at the Lawrence Berkeley Laboratory (then The University of California Radiation Laboratory). Six accelerators incorporating the Principle of Phase Stability were built in the period 1945--1954

  18. Berkeley Foundation for Opportunities in Information Technology: A Decade of Broadening Participation

    Science.gov (United States)

    Crutchfield, Orpheus S. L.; Harrison, Christopher D.; Haas, Guy; Garcia, Daniel D.; Humphreys, Sheila M.; Lewis, Colleen M.; Khooshabeh, Peter

    2011-01-01

    The Berkeley Foundation for Opportunities in Information Technology is a decade-old endeavor to expose pre-college young women and underrepresented racial and ethnic minorities to the fields of computer science and engineering, and prepare them for rigorous, university-level study. We have served more than 150 students, and graduated more than 65…

  19. Fermilab and Berkeley Lab Collaborate with Meyer Tool on Key Component for European Particle Accelerator

    CERN Multimedia

    2004-01-01

    Officials of the U.S. Department of Energy's Fermi National Accelerator Laboratory and Lawrence Berkeley National Laboratory announced yesterday the completion of a key component of the U.S. contribution to the Large Hadron Collider, a particle accelerator under construction at CERN, in Geneva, Switzerland

  20. Ernest Orlando Lawrence Berkeley National Laboratory Institutional Plan FY 2000-2004

    Energy Technology Data Exchange (ETDEWEB)

    Chartock, Mike (ed.); Hansen, Todd (ed.)

    1999-08-01

    The FY 2000-2004 Institutional Plan provides an overview of the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab, the Laboratory) mission, strategic plan, initiatives, and the resources required to fulfill its role in support of national needs in fundamental science and technology, energy resources, and environmental quality. To advance the Department of Energy's ongoing efforts to define the Integrated Laboratory System, the Berkeley Lab Institutional Plan reflects the strategic elements of our planning efforts. The Institutional Plan is a management report that supports the Department of Energy's mission and programs and is an element of the Department of Energy's strategic management planning activities, developed through an annual planning process. The Plan supports the Government Performance and Results Act of 1993 and complements the performance-based contract between the Department of Energy and the Regents of the University of California. It identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy's program planning initiatives. Preparation of the plan is coordinated by the Office of Planning and Communications from information contributed by Berkeley Lab's scientific and support divisions.

  1. Follow the Money: Engineering at Stanford and UC Berkeley during the Rise of Silicon Valley

    Science.gov (United States)

    Adams, Stephen B.

    2009-01-01

    A comparison of the engineering schools at UC Berkeley and Stanford during the 1940s and 1950s shows that having an excellent academic program is necessary but not sufficient to make a university entrepreneurial (an engine of economic development). Key factors that made Stanford more entrepreneurial than Cal during this period were superior…

  2. Information Access for a Digital Library: Cheshire II and the Berkeley Environmental Digital Library.

    Science.gov (United States)

    Larson, Ray R.; Carson, Chad

    1999-01-01

    Reviews the characteristics of the Cheshire II system that is being used to implement full-text and fielded searching of bibliographic information for the University of California Berkeley Digital Library Initiative. Examines its performance when applied to a collection of large full-text documents in the TREC Interactive Retrieval Track and its…

  3. Cyclist safety on bicycle boulevards and parallel arterial routes in Berkeley, California.

    Science.gov (United States)

    Minikel, Eric

    2012-03-01

    This study compares the safety of bicyclists riding on bicycle boulevards to those riding on parallel arterial routes in Berkeley, California. Literature on the impact of motor vehicle traffic characteristics on cyclist safety shows that high motor vehicle speeds and volumes and the presence of heavy vehicles are all detrimental to cyclist safety. This suggests that cyclists may be safer on side streets than on busy arterials. Bicycle boulevards-traffic-calmed side streets signed and improved for cyclist use-purport to offer cyclists a safer alternative to riding on arterials. Police-reported bicycle collision data and manually collected cyclist count data from bicycle boulevards and parallel arterial routes in Berkeley, California from 2003 to 2010 are used to test the hypothesis that Berkeley's bicycle boulevards have lower cyclist collision rates and a lower proportion of bicycle collisions resulting in severe injury. While no significant difference is found in the proportion of collisions that are severe, results show that collision rates on Berkeley's bicycle boulevards are two to eight times lower than those on parallel, adjacent arterial routes. The difference in collision rate is highly statistically significant, unlikely to be caused by any bias in the collision and count data, and cannot be easily explained away by self-selection or safety in numbers. Though the used dataset is limited and the study design is correlational, this study provides some evidence that Berkeley's bicycle boulevards are safer for cyclists than its parallel arterial routes. The results may be suggestive that, more generally, properly implemented bicycle boulevards can provide cyclists with a safer alternative to riding on arterials. PMID:22269506

  4. Isto é um cachimbo

    Directory of Open Access Journals (Sweden)

    Virginia Figueiredo

    2005-12-01

    Full Text Available Partindo do quadro de René Magritte, La trahison des images (Ceci n'est pas une pipe, este texto pretende tecer um comentário sobre as relações entre arte e realidade. Visando esse objetivo, tentarei interpretar a obra do pintor belga à luz do ensaio heideggeriano sobre a "Origem da obra de arte", não sem antes passar em revista alguns resultados da análise contida no livro de Michel Foucault, assim como algumas reflexões do filósofo da arte norte-americano Arthur Danto.Departing from the painting La trahison des images (Ceci n'est pas une pipe, by René Magritte, this paper intends to comment the relationships between art and reality. Aiming this objective, I will try to interpret the work of the Belgian painter according to Heidegger's essay on "The Origin of the work of art", and also reviewing some of the results of the analysis made by Michel Foulcault in his book, along with some thoughts of Arthur Danto.

  5. Leibniz's Infinitesimals: Their Fictionality, Their Modern Implementations, And Their Foes From Berkeley To Russell And Beyond

    CERN Document Server

    Katz, Mikhail G; 10.1007/s10670-012-9370-y

    2012-01-01

    Many historians of the calculus deny significant continuity between infinitesimal calculus of the 17th century and 20th century developments such as Robinson's theory. Robinson's hyperreals, while providing a consistent theory of infinitesimals, require the resources of modern logic; thus many commentators are comfortable denying a historical continuity. A notable exception is Robinson himself, whose identification with the Leibnizian tradition inspired Lakatos, Laugwitz, and others to consider the history of the infinitesimal in a more favorable light. Inspite of his Leibnizian sympathies, Robinson regards Berkeley's criticisms of the infinitesimal calculus as aptly demonstrating the inconsistency of reasoning with historical infinitesimal magnitudes. We argue that Robinson, among others, overestimates the force of Berkeley's criticisms, by underestimating the mathematical and philosophical resources available to Leibniz. Leibniz's infinitesimals are fictions, not logical fictions, as Ishiguro proposed, but ...

  6. Clinical results of stereotactic hellium-ion radiosurgery of the pituitary gland at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Levy, R.P.; Fabrikant, J.I.; Lyman, J.T.; Frankel, K.A.; Phillips, M.H.; Lawrence, J.H.; Tobias, C.A.

    1989-12-01

    The first therapeutic clinical trial using accelerated heavy-charged particles in humans was performed at Lawrence Berkeley Laboratory (LBL) for the treatment of various endocrine and metabolic disorders of the pituitary gland, and as suppressive therapy for adenohypophyseal hormone-responsive carcinomas and diabetic retinopathy. In acromegaly, Cushing's disease, Nelson's syndrome and prolactin-secreting tumors, the therapeutic goal in the 433 patients treated has been to destroy or inhibit the growth of the pituitary tumor and control hormonal hypersecretion, while preserving a functional rim of tissue with normal hormone-secreting capacity, and minimizing neurologic injury. An additional group of 34 patients was treated for nonsecreting chromophobe adenomas. This paper discusses the methods and results of stereotactic helium-ion radiosurgery of the pituitary gland at Lawrence Berkeley Laboratory. 11 refs.

  7. A Community of Scientists and Educators: The Compass Project at UC Berkeley

    Science.gov (United States)

    Roth, Nathaniel; Schwab, Josiah

    2016-01-01

    The Berkeley Compass Project is a self-formed group of graduate and undergraduate students in the physical sciences at the University of California, Berkeley. Its goals are to improve undergraduate physics education, provide opportunities for professional development, and increase retention of students from populations underrepresented in the physical sciences. For undergraduate students, the core Compass experience consists of a summer program and several seminar courses. These programs are designed to foster a diverse, collaborative student community in which students engage in authentic research practices and regular self-reflection. Graduate students, together with upper-level undergraduates, design and run all Compass programs. Compass strives to incorporate best practices from the science education literature. Experiences in Compass leave participants poised to be successful students researchers, teachers, and mentors.

  8. Construction and operation of replacement hazardous waste handling facility at Lawrence Berkeley Laboratory

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0423, for the construction and operation of a replacement hazardous waste handling facility (HWHF) and decontamination of the existing HWHF at Lawrence Berkeley Laboratory (LBL), Berkeley, California. The proposed facility would replace several older buildings and cargo containers currently being used for waste handling activities and consolidate the LBL's existing waste handling activities in one location. The nature of the waste handling activities and the waste volume and characteristics would not change as a result of construction of the new facility. Based on the analysis in the EA, DOE has determined that the proposed action would not constitute a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969, 42 USC. 4321 et seq. Therefore, an environmental impact statement is not required

  9. Clinical results of stereotactic hellium-ion radiosurgery of the pituitary gland at Lawrence Berkeley Laboratory

    International Nuclear Information System (INIS)

    The first therapeutic clinical trial using accelerated heavy-charged particles in humans was performed at Lawrence Berkeley Laboratory (LBL) for the treatment of various endocrine and metabolic disorders of the pituitary gland, and as suppressive therapy for adenohypophyseal hormone-responsive carcinomas and diabetic retinopathy. In acromegaly, Cushing's disease, Nelson's syndrome and prolactin-secreting tumors, the therapeutic goal in the 433 patients treated has been to destroy or inhibit the growth of the pituitary tumor and control hormonal hypersecretion, while preserving a functional rim of tissue with normal hormone-secreting capacity, and minimizing neurologic injury. An additional group of 34 patients was treated for nonsecreting chromophobe adenomas. This paper discusses the methods and results of stereotactic helium-ion radiosurgery of the pituitary gland at Lawrence Berkeley Laboratory. 11 refs

  10. Construction and operation of replacement hazardous waste handling facility at Lawrence Berkeley Laboratory. Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    The US Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0423, for the construction and operation of a replacement hazardous waste handling facility (HWHF) and decontamination of the existing HWHF at Lawrence Berkeley Laboratory (LBL), Berkeley, California. The proposed facility would replace several older buildings and cargo containers currently being used for waste handling activities and consolidate the LBL`s existing waste handling activities in one location. The nature of the waste handling activities and the waste volume and characteristics would not change as a result of construction of the new facility. Based on the analysis in the EA, DOE has determined that the proposed action would not constitute a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969, 42 USC. 4321 et seq. Therefore, an environmental impact statement is not required.

  11. The design and implementation of Berkeley Lab's linuxcheckpoint/restart

    Energy Technology Data Exchange (ETDEWEB)

    Duell, Jason

    2005-04-30

    This paper describes Berkeley Linux Checkpoint/Restart (BLCR), a linux kernel module that allows system-level checkpoints on a variety of Linux systems. BLCR can be used either as a stand alone system for checkpointing applications on a single machine, or as a component by a scheduling system or parallel communication library for checkpointing and restoring parallel jobs running on multiple machines. Integration with Message Passing Interface (MPI) and other parallel systems is described.

  12. Status of the Berkeley small cyclotron AMS [accelerator mass spectrometry] project

    International Nuclear Information System (INIS)

    A small, low-energy cyclotron has been designed and built at Berkeley for direct detection dating of 14C. The system combines the use of a negative ion source to reject 14N with the high resolution of a cyclotron to reject other background ions. In order to allow the dating of old and small samples, the present system incorporates a high-current external ion source and injection beamline. The system is expected to be operational by mid-1987

  13. La critique du réalisme leibnizien dans le De Motu de Berkeley.

    Directory of Open Access Journals (Sweden)

    Luc Peterschmitt

    2005-04-01

    Full Text Available L’objet de Berkeley dans le De Motu est de marquer l’autonomie de la mécanique (ou dynamique et de la métaphysique, en montrant que le concept de force tel qu’on l’utilise en mécanique ne peut servir à déterminer ce qu’il en est de la nature des choses. Pour établir cette distinction entre ces deux domaines du savoir, Berkeley à la fois s’appuie sur et critique la notion leibnizienne de force : Leibniz assure la réalité de la force dérivative (concept mécanique en la fondant sur la forme substantielle des corps, ou force primitive (concept métaphysique, qui permet d’attribuer aux corps une efficace causale. En récusant la forme substantielle comme inconcevable, Berkeley ruine alors le réalisme leibnizien, en vertu du lien posé par Leibniz lui-même entre sa métaphysique et sa dynamique. Mais du coup, cela permet à Berkeley d’instaurer un nouveau rôle à la métaphysique face à la mécanique : non plus un rôle fondateur comme celui que lui assigne Leibniz, mais un rôle critique, celui d’une instance qui dit les conditions sous lesquelles l’usage des concept est valide en science.

  14. Strategic Plan for Loss Reduction and Risk Management: University of California, Berkeley

    OpenAIRE

    Office of the Vice Provost, University of California, Berkeley; Disaster-Resistant University Steering Committee, University of California, Berkeley

    2000-01-01

    In the nearly three years since Chancellor Berdahl announced the creation of the Seismic Action plan for Facilities Enhancement and Renewal (SAFER), the UC Berkeley campus has intensified its attention to seismic safety issues. SAFER Program initiatives have changed the organizational structure, altered the landscape, and increased our understanding of the complex operational needs of the campus. This Strategic Risk Management Plan grows out of the SAFER Program, and advances its twin goals o...

  15. Gilbert Newton Lewis: his influence on physical-organic chemists at Berkeley

    International Nuclear Information System (INIS)

    A review is presented of the historical contributions of Gilbert N. Lewis to science and a discussion of the influence of Lewis on the research of the members of the physical-organic staff at Berkeley, including Melvin Calvin, during the twenties, thirties and forties. Some specific examples are discussed. Also, the effect of Lewis, his science and administrative concepts in the creation of excellence in a department of chemistry are reviewed

  16. Gilbert Newton Lewis: his influence on physical-organic chemists at Berkeley

    Energy Technology Data Exchange (ETDEWEB)

    Calvin, M.

    1982-03-01

    A review is presented of the historical contributions of Gilbert N. Lewis to science and a discussion of the influence of Lewis on the research of the members of the physical-organic staff at Berkeley, including Melvin Calvin, during the twenties, thirties and forties. Some specific examples are discussed. Also, the effect of Lewis, his science and administrative concepts in the creation of excellence in a department of chemistry are reviewed.

  17. An Introduction to the 2001 Issue of the Berkeley Planning Journa

    OpenAIRE

    Dowall, David

    2001-01-01

    Planners have always been deeply interested in and concerned about the effects of technology on human settlements. There is a rich and var­ ied literature on technics and civilization, to borrow from Mumford's brilliant account ( 193 4). Whether looking at machines, autos, comput­ ers or the Internet, this literature provides a rich treasure-trove of social and historical analysis. This issue of the Berkeley Planningjournal makes a contribution to this topic by examining the effects of techno...

  18. Progress Report on the Berkeley/Anglo-Australian Observatory High-redshift Supernova Search

    Science.gov (United States)

    Goldhaber, G.; Perlmutter, S.; Pennypacker, C.; Marvin, H.; Muller, R. A.; Couch, W.; Boyle, B.

    1990-11-01

    There are two main efforts related to supernovae in progress at Berkeley. The first is an automated supernova search for nearby supernovae, which was already discussed by Carl Pennypacker at this conference. The second is a search for distant supernovae, in the z = 0.3 to 0.5 region, aimed at measuring {Omega}. It is the latter that I want to discuss in this paper.

  19. Trending analysis of precursor events

    International Nuclear Information System (INIS)

    The Accident Sequence Precursor (ASP) Program of United States Nuclear Regulatory Commission (U.S.NRC) identifies and categorizes operational events at nuclear power plants in terms of the potential for core damage. The ASP analysis has been performed on yearly basis and the results have been published in the annual reports. This paper describes the trends in initiating events and dominant sequences for 459 precursors identified in the ASP Program during the 1969-94 period and also discusses a comparison with dominant sequences predicted in the past Probabilistic Risk Assessment (PRA) studies. These trends were examined for three time periods, 1969-81, 1984-87 and 1988-94. Although the different models had been used in the ASP analyses for these three periods, the distribution of precursors by dominant sequences show similar trends to each other. For example, the sequences involving loss of both main and auxiliary feedwater were identified in many PWR events and those involving loss of both high and low coolant injection were found in many BWR events. Also, it was found that these dominant sequences were comparable to those determined to be dominant in the predictions by the past PRAs. As well, a list of the 459 precursors identified are provided in Appendix, indicating initiating event types, unavailable systems, dominant sequences, conditional core damage probabilities, and so on. (author)

  20. PAGOSA Sample Problem. Elastic Precursor

    Energy Technology Data Exchange (ETDEWEB)

    Weseloh, Wayne N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Clancy, Sean Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-03

    A PAGOSA simulation of a flyer plate impact which produces an elastic precursor wave is examined. The simulation is compared to an analytic theory for the Mie-Grüneisen equation of state and an elastic-perfectly-plastic strength model.

  1. The little-studied cluster Berkeley 90. II. The foreground ISM

    CERN Document Server

    Apellániz, J Maíz; Sota, A; Simón-Díaz, S

    2015-01-01

    Context: Nearly one century after their discovery, the carrier(s) of Diffuse Interstellar Bands is/are still unknown and there are few sightlines studied in detail for a large number of DIBs. Aims: We want to study the ISM sightlines towards LS III +46 11 and LS III +46 12, two early-O-type stellar systems, and LS III +46 11 B, a mid-B-type star. The three targets are located in the stellar cluster Berkeley 90 and have a high extinction. Methods: We use the multi-epoch high-S/N optical spectra presented in paper I (Ma\\'iz Apell\\'aniz et al. 2015), the extinction results derived there, and additional spectra. Results: We have measured equivalent widths, velocities, and FWHMs for a large number of absorption lines in the rich ISM spectrum in front of Berkeley 90. The absorbing ISM has at least two clouds at different velocities, one with a lower column density (thinner) in the K I lines located away from Berkeley 90 and another one with a higher column density (thicker) associated with the cluster. The first cl...

  2. Ernest Orlando Berkeley National Laboratory - Fundamental and applied research on lean premixed combustion

    International Nuclear Information System (INIS)

    Ernest Orland Lawrence Berkeley National Laboratory (Berkeley Lab) is the oldest of America's national laboratories and has been a leader in science and engineering technology for more than 65 years, serving as a powerful resource to meet Us national needs. As a multi-program Department of Energy laboratory, Berkeley Lab is dedicated to performing leading edge research in the biological, physical, materials, chemical, energy, environmental and computing sciences. Ernest Orlando Lawrence, the Lab's founder and the first of its nine Nobel prize winners, invented the cyclotron, which led to a Golden Age of particle physics and revolutionary discoveries about the nature of the universe. To this day, the Lab remains a world center for accelerator and detector innovation and design. The Lab is the birthplace of nuclear medicine and the cradle of invention for medical imaging. In the field of heart disease, Lab researchers were the first to isolate lipoproteins and the first to determine that the ratio of high density to low density lipoproteins is a strong indicator of heart disease risk. The demise of the dinosaurs--the revelation that they had been killed off by a massive comet or asteroid that had slammed into the Earth--was a theory developed here. The invention of the chemical laser, the unlocking of the secrets of photosynthesis--this is a short preview of the legacy of this Laboratory

  3. Ernest Orlando Berkeley National Laboratory - Fundamental and applied research on lean premixed combustion

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Robert K.

    1999-07-07

    Ernest Orland Lawrence Berkeley National Laboratory (Berkeley Lab) is the oldest of America's national laboratories and has been a leader in science and engineering technology for more than 65 years, serving as a powerful resource to meet Us national needs. As a multi-program Department of Energy laboratory, Berkeley Lab is dedicated to performing leading edge research in the biological, physical, materials, chemical, energy, environmental and computing sciences. Ernest Orlando Lawrence, the Lab's founder and the first of its nine Nobel prize winners, invented the cyclotron, which led to a Golden Age of particle physics and revolutionary discoveries about the nature of the universe. To this day, the Lab remains a world center for accelerator and detector innovation and design. The Lab is the birthplace of nuclear medicine and the cradle of invention for medical imaging. In the field of heart disease, Lab researchers were the first to isolate lipoproteins and the first to determine that the ratio of high density to low density lipoproteins is a strong indicator of heart disease risk. The demise of the dinosaurs--the revelation that they had been killed off by a massive comet or asteroid that had slammed into the Earth--was a theory developed here. The invention of the chemical laser, the unlocking of the secrets of photosynthesis--this is a short preview of the legacy of this Laboratory.

  4. Berkeley Lab's Saul Perlmutter wins E.O. Lawrence Award; scientist's work on supernovae reveals accelerating Universe

    CERN Multimedia

    2002-01-01

    Saul Perlmutter, from Lawrence Berkeley National Laboratory Physics Division and leader of the Supernova Cosmology Project based there, has won the DOE's 2002 E.O. Lawrence Award in the physics category (2 pages).

  5. Hayward Fault rate constraints at Berkeley: Evaluation of the 335-meter Strawberry Creek offset

    Science.gov (United States)

    Williams, P. L.

    2007-12-01

    At UC Berkeley the active channel of Strawberry Creek is offset 335 meters by the Hayward fault and two abandoned channels of Strawberry Creek are laterally offset 580 and 730 meters. These relationships record the displacement of the northern Hayward fault at Berkeley over a period of tens of millennia. The Strawberry Creek site has a similar geometry to the central San Andreas fault's Wallace Creek site, which arguably provides the best geological evidence of "millennial" fault kinematics in California (Sieh and Jahns, 1984). Slip rate determinations are an essential component of overall hazard evaluation for the Hayward fault, and this site is ripe to disclose a long-term form of this parameter, to contrast with geodetic and other geological rate evidence. Large offsets at the site may lower uncertainty in the rate equation relative to younger sites, as the affect of stream abandonment age, generally the greatest source of rate uncertainty, is greatly reduced. This is helpful here because it more-than-offsets uncertainties resulting from piercing projections to the fault. Strawberry Creek and its ancestral channels suggest west-side-up vertical deformation across the Hayward fault at this location. The development of the vertical deformation parameter will complement ongoing geodetic measurements, particularly InSAR, and motivate testing of other geological constraints. Up-to-the-west motion across the Hayward fault at Berkeley has important implications for the partitioning of strain and kinematics of the northern Hayward fault, and may explain anomalous up-on-the-west landforms elsewhere along the fault. For example, geological features of the western Berkeley Hills are consistent with rapid and recent uplift to the west of the fault. On the basis of a preliminary analysis of the offset channels of Strawberry Creek, up-to-the-west uplift is about 0.5mm/yr across the Hayward fault at Berkeley. If this is in fact the long-term rate, the 150 m height of the Hills

  6. Costs, Culture, and Complexity: An Analysis of Technology Enhancements in a Large Lecture Course at UC Berkeley

    OpenAIRE

    Harley, Diane; Henke, Jonathan; Lawrence, Shannon; McMartin, Flora; Maher, Michael; Gawlik, Marytza; Muller, Parisa

    2003-01-01

    As colleges and universities nationwide anticipate enrolling more than two million new students over the next decade, UC Berkeley is exploring options for serving more students, more cost effectively, in large lecture courses. This research project analyzes economic and pedagogical questions related to the use of on-line lecture and laboratory material in a large introductory chemistry course at UC Berkeley. We undertook a quasi-experimental two-year study to determine if the utilization of o...

  7. Environmental assessment for the proposed construction and operation of a Genome Sequencing Facility in Building 64 at Lawrence Berkeley Laboratory, Berkeley, California

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    This document is an Environmental Assessment (EA) for a proposed project to modify 14,900 square feet of an existing building (Building 64) at Lawrence Berkeley Laboratory (LBL) to operate as a Genome Sequencing Facility. This EA addresses the potential environmental impacts from the proposed modifications to Building 64 and operation of the Genome Sequencing Facility. The proposed action is to modify Building 64 to provide space and equipment allowing LBL to demonstrate that the Directed DNA Sequencing Strategy can be scaled up from the current level of 750,000 base pairs per year to a facility that produces over 6,000,000 base pairs per year, while still retaining its efficiency.

  8. The Innate Lymphoid Cell Precursor.

    Science.gov (United States)

    Ishizuka, Isabel E; Constantinides, Michael G; Gudjonson, Herman; Bendelac, Albert

    2016-05-20

    The discovery of tissue-resident innate lymphoid cell populations effecting different forms of type 1, 2, and 3 immunity; tissue repair; and immune regulation has transformed our understanding of mucosal immunity and allergy. The emerging complexity of these populations along with compounding issues of redundancy and plasticity raise intriguing questions about their precise lineage relationship. Here we review advances in mapping the emergence of these lineages from early lymphoid precursors. We discuss the identification of a common innate lymphoid cell precursor characterized by transient expression of the transcription factor PLZF, and the lineage relationships of innate lymphoid cells with conventional natural killer cells and lymphoid tissue inducer cells. We also review the rapidly growing understanding of the network of transcription factors that direct the development of these lineages. PMID:27168240

  9. The Innate Lymphoid Cell Precursor.

    Science.gov (United States)

    Ishizuka, Isabel E; Constantinides, Michael G; Gudjonson, Herman; Bendelac, Albert

    2016-05-20

    The discovery of tissue-resident innate lymphoid cell populations effecting different forms of type 1, 2, and 3 immunity; tissue repair; and immune regulation has transformed our understanding of mucosal immunity and allergy. The emerging complexity of these populations along with compounding issues of redundancy and plasticity raise intriguing questions about their precise lineage relationship. Here we review advances in mapping the emergence of these lineages from early lymphoid precursors. We discuss the identification of a common innate lymphoid cell precursor characterized by transient expression of the transcription factor PLZF, and the lineage relationships of innate lymphoid cells with conventional natural killer cells and lymphoid tissue inducer cells. We also review the rapidly growing understanding of the network of transcription factors that direct the development of these lineages.

  10. Precursor polymer compositions comprising polybenzimidazole

    Energy Technology Data Exchange (ETDEWEB)

    Klaehn, John R.; Peterson, Eric S.; Orme, Christopher J.

    2015-07-14

    Stable, high performance polymer compositions including polybenzimidazole (PBI) and a melamine-formaldehyde polymer, such as methylated, poly(melamine-co-formaldehyde), for forming structures such as films, fibers and bulky structures. The polymer compositions may be formed by combining polybenzimidazole with the melamine-formaldehyde polymer to form a precursor. The polybenzimidazole may be reacted and/or intertwined with the melamine-formaldehyde polymer to form the polymer composition. For example, a stable, free-standing film having a thickness of, for example, between about 5 .mu.m and about 30 .mu.m may be formed from the polymer composition. Such films may be used as gas separation membranes and may be submerged into water for extended periods without crazing and cracking. The polymer composition may also be used as a coating on substrates, such as metal and ceramics, or may be used for spinning fibers. Precursors for forming such polymer compositions are also disclosed.

  11. PKP precursors : Implications for global scatterers

    NARCIS (Netherlands)

    Waszek, Lauren; Thomas, Christine; Deuss, Arwen

    2015-01-01

    Precursors to the core phase PKP are generated by scattering of seismic energy from heterogeneities in the mantle. Here we examine a large global data set of PKP precursors in individual seismograms and array data, to better understand scattering locations. The precursor amplitudes from individual s

  12. Exploratory Research and Development Fund, FY 1990. Report on Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1992-05-01

    The Lawrence Berkeley Laboratory Exploratory R&D Fund FY 1990 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of an Exploratory R&D Fund (ERF) planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The research areas covered in this report are: Accelerator and fusion research; applied science; cell and molecular biology; chemical biodynamics; chemical sciences; earth sciences; engineering; information and computing sciences; materials sciences; nuclear science; physics and research medicine and radiation biophysics.

  13. Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-07-02

    In connection with the Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 67 CD-ROM diskettes (approximately 35 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. This paper contains a list of the CD-ROMs available.

  14. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-07-02

    In connection with the Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 67 CD-ROM diskettes (approximately 35 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. This paper contains a list of the CD-ROMs available.

  15. High energy nucleus--nucleus studies at the Berkeley Bevalac. [Survey

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, L.S.

    1976-09-01

    A survey of high-energy nucleus--nucleus experiments performed at the Berkeley Bevalac Facility is presented. Experimental results are divided into the general areas of peripheral and central collisions. Results on projectile and target fragmentation, total cross-section measurements, pion and photon production, and charged-particle multiplicities are stressed. Recently, there have been theoretical predictions concerning the possibility of observing new phenomena such as shock waves, pion condensates, or collapsed nuclear matter. Existing data relevant to some of these speculations are discussed. A brief discussion of future developments with high-energy nuclear beams is also presented. 27 figures, 1 table.

  16. Monorquidismo em um equino marchador

    Directory of Open Access Journals (Sweden)

    Jéssica Fontana de Magalhães

    2015-06-01

    Full Text Available O monorquidismo é um quadro raramente descrito em equinos, que não apresenta descrições prévias na literatura nacional. Trata-se de um equino adulto brasileiro, com oito anos de idade, sem raça definida, porém com características de raças de origem nacional. Por abordagem inguinal do lado esquerdo, localizou-se a túnica vaginal intacta, que, aberta, continha a cauda de um epidídimo mal formado, o ducto deferente e um delgado pedículo vascular, mas sem indícios de testículo. Exames histológicos e hormonais confirmaram a ausência de tecido testicular. Conclui-se que os exames histológicos e hormonais são essenciais para o diagnóstico de monorquidismo que, apesar de raro, também pode acometer equinos nacionais

  17. Precursor films in wetting phenomena

    OpenAIRE

    Popescu, M. N.; Oshanin, G.; Dietrich, S.; Cazabat, A. -M.

    2012-01-01

    The spontaneous spreading of non-volatile liquid droplets on solid substrates poses a classic problem in the context of wetting phenomena. It is well known that the spreading of a macroscopic droplet is in many cases accompanied by a thin film of macroscopic lateral extent, the so-called precursor film, which emanates from the three-phase contact line region and spreads ahead of the latter with a much higher speed. Such films have been usually associated with liquid-on-solid systems, but in t...

  18. Environmental health-risk assessment for tritium releases at the National Tritium Labeling Facility at Lawrence Berkeley National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.; Brand, K.P. [Lawrence Livermore National Lab., CA (United States). Health and Ecological Assessment Div.; Shan, C. [Lawrence Berkeley National Lab., CA (United States). Earth Sciences Div.

    1997-04-01

    This risk assessment calculates the probability of experiencing health effects, including cancer incidence due to tritium exposure for three groups of people: (1) LBNL workers near the LBNL facility--Building 75--that uses tritium; (2) other workers at LBNL and nearby neighbors; and (3) people who use the UC Berkeley campus area, and some Berkeley residents. All of these groups share the same probability of health effects from the background radiation from natural sources in the Berkeley area environment, including an increased risk of developing a cancer of 11,000 chances per million. In calculating risk the authors assumed continuous operation in Building 75 for at least a human lifetime. Under this assumption, LBNL workers located near Building 75 have an additional risk of 60 chances out of one million to suffer a cancer; other workers at LBNL and people who live near LBNL have an additional risk of six chances out of one million over a lifetime of exposure; and users of the UC Berkeley campus area and other residents of Berkeley have an additional risk of less than once chance out of one million over a lifetime.

  19. Environmental health-risk assessment for tritium releases at the National Tritium Labeling Facility at Lawrence Berkeley National Laboratory

    International Nuclear Information System (INIS)

    This risk assessment calculates the probability of experiencing health effects, including cancer incidence due to tritium exposure for three groups of people: (1) LBNL workers near the LBNL facility--Building 75--that uses tritium; (2) other workers at LBNL and nearby neighbors; and (3) people who use the UC Berkeley campus area, and some Berkeley residents. All of these groups share the same probability of health effects from the background radiation from natural sources in the Berkeley area environment, including an increased risk of developing a cancer of 11,000 chances per million. In calculating risk the authors assumed continuous operation in Building 75 for at least a human lifetime. Under this assumption, LBNL workers located near Building 75 have an additional risk of 60 chances out of one million to suffer a cancer; other workers at LBNL and people who live near LBNL have an additional risk of six chances out of one million over a lifetime of exposure; and users of the UC Berkeley campus area and other residents of Berkeley have an additional risk of less than once chance out of one million over a lifetime

  20. Searching for multiple stellar populations in the massive, old open cluster Berkeley 39

    CERN Document Server

    Bragaglia, A; Carretta, E; D'Orazi, V; Sneden, C; Lucatello, S

    2012-01-01

    The most massive star clusters include several generations of stars with a different chemical composition (mainly revealed by an Na-O anti-correlation) while low-mass star clusters appear to be chemically homogeneous. We are investigating the chemical composition of several clusters with masses of a few 10^4 Msun to establish the lower mass limit for the multiple stellar population phenomenon. Using FLAMES@VLT spectra we determine abundances of Fe, O, Na, and several other elements (alpha, Fe-peak, and neutron-capture elements) in the old open cluster Berkeley 39. This is a massive open cluster: M~10^4 Msun, approximately at the border between small globular clusters and large open clusters. Our sample size of about 30 stars is one of the largest studied for abundances in any open cluster to date, and will be useful to determine improved cluster parameters, such as age, distance, and reddening when coupled with precise, well-calibrated photometry. We find that Berkeley 39 is slightly metal-poor, =-0.20, in ag...

  1. Catalog of Research Abstracts, 1993: Partnership opportunities at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The 1993 edition of Lawrence Berkeley Laboratory`s Catalog of Research Abstracts is a comprehensive listing of ongoing research projects in LBL`s ten research divisions. Lawrence Berkeley Laboratory (LBL) is a major multi-program national laboratory managed by the University of California for the US Department of Energy (DOE). LBL has more than 3000 employees, including over 1000 scientists and engineers. With an annual budget of approximately $250 million, LBL conducts a wide range of research activities, many that address the long-term needs of American industry and have the potential for a positive impact on US competitiveness. LBL actively seeks to share its expertise with the private sector to increase US competitiveness in world markets. LBL has transferable expertise in conservation and renewable energy, environmental remediation, materials sciences, computing sciences, and biotechnology, which includes fundamental genetic research and nuclear medicine. This catalog gives an excellent overview of LBL`s expertise, and is a good resource for those seeking partnerships with national laboratories. Such partnerships allow private enterprise access to the exceptional scientific and engineering capabilities of the federal laboratory systems. Such arrangements also leverage the research and development resources of the private partner. Most importantly, they are a means of accessing the cutting-edge technologies and innovations being discovered every day in our federal laboratories.

  2. NGC 1817, NGC 2141, and Berkeley 81: three BOCCE clusters of intermediate age

    CERN Document Server

    Donati, P; Bragaglia, A; Cignoni, M; Tosi, M

    2013-01-01

    In this paper we analyse the evolutionary status of three open clusters: NGC 1817, NGC 2141, and Berkeley 81. They are all of intermediate age, two are located in the Galactic anti-centre direction while the third one is located in the Galactic centre direction. All of them were observed with LBC@LBT using the Bessel B, V, and I filters. The cluster parameters have been obtained using the synthetic colour-magnitude diagram (CMD) method, i.e. the direct comparison of the observational CMDs with a library of synthetic CMDs generated with different evolutionary sets (Padova, FRANEC, and FST). This analysis shows that NGC 1817 has subsolar metallicity, age between 0.8 and 1.2 Gyr, reddening E(B-V) in the range 0.21 and 0.34, and distance modulus (m-M)_0 of about 10.9; NGC 2141 is older, with age in the range 1.25 and 1.9 Gyr, E(B-V) between 0.36 and 0.45, (m-M)_0 between 11.95 and 12.21, and subsolar metallicity; Berkeley~81 has metallicity about solar, with age between 0.75 and 1.0 Gyr, has reddening E(B-V)~0.90...

  3. The old anticentre open cluster Berkeley 32: membership and fundamental parameters

    CERN Document Server

    D'Orazi, V; Fabrizio, L D; Held, E V; Tosi, M

    2006-01-01

    We have obtained medium-low resolution spectroscopy and BVI CCD imaging of Berkeley 32, an old open cluster which lies in the anticentre direction. From the radial velocities of 48 stars in the cluster direction we found that 31 of them, in crucial evolutionary phases, are probable cluster members, with an average radial velocity of +106.7 (sigma = 8.5) km/s. From isochrone fitting to the colour magnitude diagrams of Berkeley 32 we have obtained an age of 6.3 Gyr, (m-M)0 = 12.48 and E(B-V) = 0.10. The best fit is obtained with Z=0.008. A consistent distance, (m-M)0 ~= 12.6 +/- 0.1, has been derived from the mean magnitude of red clump stars with confirmed membership; we may assume (m-M)0 ~= 12.55 +/- 0.1. The colour magnitude diagram of the nearby field observed to check for field stars contamination looks intriguingly similar to that of the Canis Major overdensity.

  4. Environmental assessment for the recycling of slightly activated copper coil windings from the 184-Inch Cyclotron at Lawrence Berkeley Laboratory, Berkeley, California

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-02

    The proposed action is to recycle slightly activated copper that is currently stored in a warehouse leased by Lawrence Berkeley Laboratory (LBL) to a scrap metal dealer. Subsequent reutilization of the copper would be unrestricted. This document addresses the potential environmental effects of recycling and reutilizing the activated copper. In addition, the potential environmental effects of possible future uses by the dealer are addressed. Direct environmental effects from the proposed action are assessed, such as air emissions from reprocessing the activated copper, as well as indirect beneficial effects, such as averting air emissions that would result from mining and smelting an equivalent quantity of copper ore. Evaluation of the human health impacts of the proposed action focuses on the pertinent issues of radiological doses and protection of workers and the public. Five alternatives to the proposed action are considered, and their associated potential impacts are addressed. The no-action alternative is the continued storage of the activated copper at the LBL warehouse. Two recycling alternatives are considered: recycling the activated copper at the Scientific Ecology Group (SEG) facility for re-use at a DOE facility and selling or giving the activated copper to a foreign government. In addition, two disposal alternatives evaluate the impacts attributable to disposing of the activated copper either at a local sanitary landfill or at the Hanford Low-Level Waste Burial Site. The proposed project and alternatives include no new construction or development of new industry.

  5. Es geht nicht um "Versagen"!

    OpenAIRE

    Crome, Erhard

    2010-01-01

    Die sich zunächst um Griechenland rankende Krise wurde zu einer europäischen, die den Euro bedroht. Allenthalben wird die Frage gestellt: Wer ist schuld? In deutschen Groß-Medien wird auf das Zögern der derzeitigen Bundesregierung verwiesen. Der Euro rutschte in die Gefahrenzone. Aber ist der Verweis auf falsche Politik die Antwort auf die Frage nach dem erneuten Aufbrechen der Finanzkrise?

  6. para um museu da praia

    OpenAIRE

    Severo, Carlos Manuel de Oliveira, 1958-

    2011-01-01

    Tese de mestrado, Museologia e museografia, Universidade de Lisboa, Faculdade de Belas Artes, 2011 O documento possui um ficheiro com Anexos em Word, sem possibilidade de conversão que apenas poderá ser consultado na Biblioteca da FBAUL Due to the exceptional weather, climatic and morphologic characteristics of the west region of Lisbon, seaside holidaying was born and grew in Costa do Sol in Portugal. Sea bathing first started for therapeutic reasons, but it was quickly transformed ...

  7. Qualidade total: Um novo paradigma?

    Directory of Open Access Journals (Sweden)

    Suzana da Rosa Tolfo

    1999-01-01

    Full Text Available Nos últimos anos, o movimento para a implantação da Gestão da Qualidade Total vem crescendo ao redor do mundo. Em razão disso, há uma diversidade de ações realizadas com o nome de "Qualidade Total'. Uma revisão da teoria é complexa, porque existem muitos autores que tratam da questão. Eles escolhem diferentes perspectivas de análises (teóricas e empíricas e há dificuldades em se identificar um corpo conceitual. Há uma ampla difusão de modelos, ferramentas, técnicas, mercado e consultores. Essa popularidade, muitas vezes, faz com que determinadas organizações adotem essa forma de gestão do trabalho sem o conhecimento necessário das implicações que um modelo dessa ordem representa; especialmente no caso brasileiro, suscetível a proposições importadas. O presente artigo propõe um exame daquilo que os fundadores têm articulado sobre TQM, as principais críticas nesta direção e a avaliação de como vem sendo aplicadono nosso país.

  8. Photometric study of W UMa type binaries in the old open cluster Berkeley 39

    Institute of Scientific and Technical Information of China (English)

    Kandulapati Sriram; Yellapragada Ravi Kiron; Pasagada Vivekananda Rao

    2009-01-01

    The study of W UMa binary systems gives a wealth of information about their nature as well as their parent bodies(if any).like clusters.In this paper,we present the Ⅰ passband photometric solutions of four W UMa binaries in the open cluster Berkeley 39 using the latest version of the W-D program.The result shows that two binary systems are W-subtype W UMa binary systems and the other two systems are H-subtype W UMa binary systems.No third body has been found in any of the four systems.we found a correlation between the period and mass-ratio as well as temperature and mass-ratio for the respective variables,which is similar to the relationship between mass ratio and total mass of the contact binaries as shown by van't Veer and Li et al.

  9. Studies, Transport and Treatment Concept for Boilers from Berkeley NPP, England - 13599

    International Nuclear Information System (INIS)

    In November 2011 Studsvik was awarded a contract to transport five decommissioned boilers from the Berkeley Nuclear Licensed Site in the UK to the Studsvik Nuclear Site in Sweden for metal treatment and recycling. A key objective of the project was to remove the boilers from the site by 31 March 2012 and this was successfully achieved with all boilers off site by 22 March and delivered to Studsvik on 6 April. Four boilers have been processed and the fifth is planned for completion by end of December 2012.The project had many challenges including a very tight timescale and has been successfully delivered to cost and ahead of the baseline programme. This paper describes the project and the experience gained from treatment of the first four boilers. It is the first UK project to send large components overseas for recycling and provides new insight into the processing of Magnox gas-circuit components. (authors)

  10. Fifty Years of Progress, 1937-1987 [Lawrence Berkeley Laboratory (LBL, LBNL)

    Science.gov (United States)

    Budinger, T. F. (ed.)

    1987-01-01

    This booklet was prepared for the 50th anniversary of medical and biological research at the Donner Laboratory and the Lawrence Berkeley Laboratory of the University of California. The intent is to present historical facts and to highlight important facets of fifty years of accomplishments in medical and biological sciences. A list of selected scientific publications from 1937 to 1960 is included to demonstrate the character and lasting importance of early pioneering work. The organizational concept is to show the research themes starting with the history, then discoveries of medically important radionuclides, then the use of accelerated charged particles in therapy, next human physiology studies then sequentially studies of biology from tissues to macromolecules; and finally studies of the genetic code.

  11. Studies, Transport and Treatment Concept for Boilers from Berkeley NPP, England - 13599

    Energy Technology Data Exchange (ETDEWEB)

    Wirendal, Bo [Studsvik Nuclear AB (Sweden); Saul, David; Robinson, Joe; Davidson, Gavin [Studsvik UK Ltd (United Kingdom)

    2013-07-01

    In November 2011 Studsvik was awarded a contract to transport five decommissioned boilers from the Berkeley Nuclear Licensed Site in the UK to the Studsvik Nuclear Site in Sweden for metal treatment and recycling. A key objective of the project was to remove the boilers from the site by 31 March 2012 and this was successfully achieved with all boilers off site by 22 March and delivered to Studsvik on 6 April. Four boilers have been processed and the fifth is planned for completion by end of December 2012.The project had many challenges including a very tight timescale and has been successfully delivered to cost and ahead of the baseline programme. This paper describes the project and the experience gained from treatment of the first four boilers. It is the first UK project to send large components overseas for recycling and provides new insight into the processing of Magnox gas-circuit components. (authors)

  12. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1993-01-16

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 72 CD-ROM diskettes (approximately 37 gigabytes) are on line via the Unix file server cedrcd.lbl.gov''. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user's application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access. Please contact Deane Merrill (dwmerrill lbl.gov) if you wish to make use of the data.

  13. Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1993-03-12

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 89 CD-ROM diskettes (approximately 45 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access.

  14. Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1993-01-16

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 72 CD-ROM diskettes (approximately 37 gigabytes) are on line via the Unix file server ``cedrcd.lbl.gov``. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access. Please contact Deane Merrill (dwmerrill@lbl.gov) if you wish to make use of the data.

  15. Leading time domain seismic precursors

    Science.gov (United States)

    Boucouvalas, A. C.; Gkasios, M.; Keskebes, A.; Tselikas, N. T.

    2014-08-01

    The problem of predicting the occurrence of earthquakes is threefold. On one hand it is necessary to predict the date and magnitude of an earthquake, and on the other hand the location of the epicenter. In this work after a brief review of the state of earthquake prediction research, we report on a new leading time precursor for determining time onset of earthquake occurrence. We report the linking between earthquakes of the past with those which happen in the future via Fibonacci, Dual and Lucas numbers (FDL) numbers. We demonstrate it here with two example seed earthquakes at least 100 years old. Using this leading indicator method we can predict significant earthquake events >6.5R, with good accuracy approximately +- 1 day somewhere in the world. From a single seed we produce at least 100 trials simultaneously of which 50% are correct to +- 1day. The indicator is based on Fibonacci, Dual and Lucas numbers (FDL). This result hints that the log periodic FDL numbers are at the root of the understanding of the earthquake mechanism. The theory is based on the assumption that each occurred earthquake discontinuity can be thought of as a generating source of FDL time series. (The mechanism could well be linked to planetary orbits). When future dates are derived from clustering and convergence from previous strong earthquake dates at an FDL time distance, then we have a high probability for an earthquake to occur on that date. We set up a real time system which generates FDL time series from each previous significant earthquake (>7R) and we produce a year to year calendar of high probability earthquake dates. We have tested this over a number of years with considerable success. We have applied this technique for strong (>7R) earthquakes across the globe as well as on a restricted region such as the Greek geographic region where the magnitude is small (>4R-6.5R). In both cases the success of the method is impressive. It is our belief that supplementing this method with

  16. Historicismo: notas sobre um paradigma

    OpenAIRE

    José D’Assunção Barros

    2012-01-01

    Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder,...

  17. Rheological behavior of precursor PPV monolayers

    NARCIS (Netherlands)

    Luinge, JW; Nijboer, GW; Hagting, JG; Vorenkamp, EJ; Fuller, GG; Schouten, AJ

    2004-01-01

    The rheological behavior of different precursor poly(p-phenylene vinylene) (prec-PPV) monolayers at the air-water interface was investigated using an interfacial stress rheometer (ISR). This device nicely reveals a transition of the precursor poly(2,5-dimethoxy-1,4 phenylene vinylene) (prec-DMePPV)

  18. Berkeley Lab's Saul Perlmutter wins E.O. Lawrence Award scientist's work on supernovae reveals accelerating universe

    CERN Multimedia

    2002-01-01

    "Saul Perlmutter, a member of Lawrence Berkeley National Laboratory's Physics Division and leader of the international Supernova Cosmology Project based there, has won the Department of Energy's 2002 E.O. Lawrence Award in the physics category" (1/2 page).

  19. Assessing Information Literacy among Undergraduates: A Discussion of the Literature and the University of California-Berkeley Assessment Experience.

    Science.gov (United States)

    Maughan, Patricia Davitt

    2001-01-01

    Since 1994, the Teaching Library at the University of California-Berkeley has conducted an ongoing Survey of Information Literacy Competencies in selected academic departments to measure the "lower-order" information literacy skills of graduating seniors. The survey reveals that students think they know more about accessing information and…

  20. Precursor films in wetting phenomena

    International Nuclear Information System (INIS)

    The spontaneous spreading of non-volatile liquid droplets on solid substrates poses a classic problem in the context of wetting phenomena. It is well known that the spreading of a macroscopic droplet is in many cases accompanied by a thin film of macroscopic lateral extent, the so-called precursor film, which emanates from the three-phase contact line region and spreads ahead of the latter with a much higher speed. Such films have been usually associated with liquid-on-solid systems, but in the last decade similar films have been reported to occur in solid-on-solid systems. While the situations in which the thickness of such films is of mesoscopic size are fairly well understood, an intriguing and yet to be fully understood aspect is the spreading of microscopic, i.e. molecularly thin, films. Here we review the available experimental observations of such films in various liquid-on-solid and solid-on-solid systems, as well as the corresponding theoretical models and studies aimed at understanding their formation and spreading dynamics. Recent developments and perspectives for future research are discussed. (topical review)

  1. Precursor films in wetting phenomena.

    Science.gov (United States)

    Popescu, M N; Oshanin, G; Dietrich, S; Cazabat, A-M

    2012-06-20

    The spontaneous spreading of non-volatile liquid droplets on solid substrates poses a classic problem in the context of wetting phenomena. It is well known that the spreading of a macroscopic droplet is in many cases accompanied by a thin film of macroscopic lateral extent, the so-called precursor film, which emanates from the three-phase contact line region and spreads ahead of the latter with a much higher speed. Such films have been usually associated with liquid-on-solid systems, but in the last decade similar films have been reported to occur in solid-on-solid systems. While the situations in which the thickness of such films is of mesoscopic size are fairly well understood, an intriguing and yet to be fully understood aspect is the spreading of microscopic, i.e. molecularly thin, films. Here we review the available experimental observations of such films in various liquid-on-solid and solid-on-solid systems, as well as the corresponding theoretical models and studies aimed at understanding their formation and spreading dynamics. Recent developments and perspectives for future research are discussed. PMID:22627067

  2. Dermatite multifatorial em um canino

    Directory of Open Access Journals (Sweden)

    C.B. Matos

    2012-12-01

    Full Text Available Relatou-se um caso clínico de dermatite multifatorial em cão, envolvendo Demodex canis, Sporothrix schenckii e bactérias dos gêneros Staphylococcus e Streptococcus. O animal, macho, da raça Pit Bull, com um ano e três meses de idade, apresentou lesões úmidas, hiperêmicas, descamativas e ulcerativas nas regiões do pescoço e do tórax. Exames laboratoriais confirmaram o diagnóstico de infecção concomitante por fungo, bactéria e parasito. A terapia antimicrobiana com moxidectina, itraconazol e amoxicilina foi efetiva, com remissão dos sinais clínicos após 30 dias de tratamento. Este relato salienta a importância do diagnóstico de certeza, que foi determinante para estabelecimento da terapêutica adequada e recuperação do animal.

  3. Preparation of precursor for stainless steel foam

    Institute of Scientific and Technical Information of China (English)

    ZHOU Xiang-yang; LI Shan-ni; LI Jie; LIU Ye-xiang

    2008-01-01

    The effects of polyurethane sponge pretreatment and slurry compositions on the slurry loading in precursor were discussed, and the,performances of stainless steel foams prepared from precursors with different slurry loadings and different particle sizes of the stainless steel powder were also investigated. The experimental results show that the pretreatment of sponge with alkaline solution is effective to reduce the jam of cells in precursor and ensure the slurry to uniformly distribute in sponge, and it is also an effective method for increasing the slurry loading in precursor; the mass fraction of additive A and solid content in slurry greatly affect the slurry loading in precursor, when they are kept in 9%-13% and 52%-75%, respectively, the stainless steel foam may hold excellent 3D open-cell network structure and uniform muscles; the particle size of the stainless steel powder and the slurry loading in precursor have great effects on the bending strength, apparent density and open porosity of stainless steel foam; when the stainless steel powder with particle size of 44 tan and slurry loading of 0.5 g/cm3 in precursor are used, a stainless steel foam can be obtained, which has open porosity of 81.2%, bending strength of about 51.76 MPa and apparent density of about 1.0 g/cm3.

  4. Historicismo: notas sobre um paradigma

    Directory of Open Access Journals (Sweden)

    José D’Assunção Barros

    2012-08-01

    Full Text Available Este artigo tem por objetivo desenvolver algumas considerações sobre o Historicismo e sua possibilidade de ser examinado como um dos paradigmas que concorrem para o estabelecimento de uma história científica no século XIX. O primeiro ponto tratado é relativo às origens do paradigma Historicista na transição do século XVIII para o século XIX. Na sequência, aproximamo-nos da apropriação conservadora do paradigma historicista no novo contexto no qual a burguesia européia está assentada no Poder, combinando-se com a consolidação dos modernos estados-nações. A especificação das características deste paradigma constituem o principal ponto de análise

  5. Synthesis and structures of metal chalcogenide precursors

    Science.gov (United States)

    Hepp, Aloysius F.; Duraj, Stan A.; Eckles, William E.; Andras, Maria T.

    1990-01-01

    The reactivity of early transition metal sandwich complexes with sulfur-rich molecules such as dithiocarboxylic acids was studied. Researchers recently initiated work on precursors to CuInSe2 and related chalcopyrite semiconductors. Th every high radiation tolerance and the high absorption coefficient of CuInSe2 makes this material extremely attractive for lightweight space solar cells. Their general approach in early transition metal chemistry, the reaction of low-valent metal complexes or metal powders with sulfur and selenium rich compounds, was extended to the synthesis of chalcopyrite precursors. Here, the researchers describe synthesis, structures, and and routes to single molecule precursors to metal chalcogenides.

  6. Atomic Layer Deposition from Dissolved Precursors.

    Science.gov (United States)

    Wu, Yanlin; Döhler, Dirk; Barr, Maïssa; Oks, Elina; Wolf, Marc; Santinacci, Lionel; Bachmann, Julien

    2015-10-14

    We establish a novel thin film deposition technique by transferring the principles of atomic layer deposition (ALD) known with gaseous precursors toward precursors dissolved in a liquid. An established ALD reaction behaves similarly when performed from solutions. "Solution ALD" (sALD) can coat deep pores in a conformal manner. sALD offers novel opportunities by overcoming the need for volatile and thermally robust precursors. We establish a MgO sALD procedure based on the hydrolysis of a Grignard reagent.

  7. Precursor Parameter Identification for IGBT Prognostics

    Data.gov (United States)

    National Aeronautics and Space Administration — Precursor parameters have been identified to enable development of a prognostic approach for insulated gate bipolar transistors (IGBT). The IGBT were subjected to...

  8. Profiling Identifies Precursor Suspects: Notch Family Again!

    OpenAIRE

    Breunig, Joshua J.; Rakic, Pasko

    2010-01-01

    Newborn neurons in the adult dentate gyrus pass through several distinct precursor and progenitor classes prior to differentiation. In this issue of Cell Stem Cell, Lugert et al. (2010) characterized their strikingly different proliferative behaviors after neurogenic stimuli or aging.

  9. Progress in molecular precursors for electronic materials

    Energy Technology Data Exchange (ETDEWEB)

    Buhro, W.E. [Washington Univ., St. Louis, MO (United States)

    1996-09-01

    Molecular-precursor chemistry provides an essential underpinning to all electronic-materials technologies, including photovoltaics and related areas of direct interest to the DOE. Materials synthesis and processing is a rapidly developing field in which advances in molecular precursors are playing a major role. This article surveys selected recent research examples that define the exciting current directions in molecular-precursor science. These directions include growth of increasingly complex structures and stoichiometries, surface-selective growth, kinetic growth of metastable materials, growth of size-controlled quantum dots and quantum-dot arrays, and growth at progressively lower temperatures. Continued progress in molecular-precursor chemistry will afford precise control over the crystal structures, nanostructures, and microstructures of electronic materials.

  10. Rational design of precursors for oxide ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Apblett, A.W.; Georgieva, G. [Tulane Univ., New Orleans, LA (United States)

    1993-12-31

    The use of molecular species as precursors for inorganic materials has received considerable attention in recent years. As a result, metal-organic precursors are becoming increasingly sophisticated as particular decomposition mechanisms and specific stoichiometry are integrated into their design. The authors have pursued both of these design aspects for the development of low-temperature precursors for mono- and bi-metallic oxide materials. Thus, a great variety of metal complexes with 2- and 3-oximinocarboxylic acids, acyloin oximes, 2,4-diols, and diacetone alcohol have been prepared and their thermal behavior investigated. The results of this investigation and their application to the preparation of a variety of metal, oxide ceramics, will be discussed. Particular attention will be paid to precursors for alumina, titania, zirconia, perovskite-phase ferroelectric materials, and ferrites.

  11. Genotoxicity and antigenotoxicity assessment of shiitake (Lentinula edodes (Berkeley Pegler using the Comet assay

    Directory of Open Access Journals (Sweden)

    CK Miyaji

    2004-01-01

    Full Text Available The mushroom shiitake (Lentinula edodes (Berkeley Pegler is been widely consumed in many countries, including Brazil, because of its pleasant flavor and reports of its therapeutic properties, although there is little available information on the genotoxicity and/or antigenotoxicity of this mushroom. We used the Comet assay and HEp-2 cells to evaluate the in vitro genotoxic and antigenotoxic activity of aqueous extracts of shiitake prepared in three different concentrations (0.5, 1.0 and 1.5 mg/mL and three different temperatures (4, 22 and 60 °C, using methyl methanesulfonate (MMS as a positive control and untreated cells as a negative control. Two concentrations (1.0 and 1.5 mg/mL of extract prepared at 4 °C and all of the concentrations prepared at 22 ± 2 and 60 °C showed moderate genotoxic activity. To test the protective effect of the three concentrations of the extracts against the genotoxicity induced by methyl methanesulfonate, three protocols were used: pre-treatment, simultaneous-treatment and post-treatment. Treatments were repeated for all combinations of preparation temperature and concentration. Two extracts (22 ± 2 °C 1.0 mg/mL (simultaneous-treatment and 4 °C 0.5 mg/mL (post-treatment showed antigenotoxic activity.

  12. Berkeley Supernova Ia Program II: Initial Analysis of Spectra Obtained Near Maximum Brightness

    CERN Document Server

    Silverman, Jeffrey M; Filippenko, Alexei V

    2012-01-01

    In this second paper in a series we present measurements of spectral features of 432 low-redshift (z < 0.1) optical spectra of 261 Type Ia supernovae (SNe Ia) within 20 d of maximum brightness. The data were obtained from 1989 through the end of 2008 as part of the Berkeley SN Ia Program (BSNIP) and are presented in BSNIP I (Silverman et al., submitted). We describe in detail our method of automated, robust spectral feature definition and measurement which expands upon similar previous studies. Using this procedure, we attempt to measure expansion velocities, pseudo-equivalent widths (pEW), spectral feature depths, and fluxes at the centre and endpoints of each of nine major spectral feature complexes. A sanity check of the consistency of our measurements is performed using our data (as well as a separate spectral dataset). We investigate how velocity and pEW evolve with time and how they correlate with each other. Various spectral classification schemes are employed and quantitative spectral differences a...

  13. Ernest Orlando Lawrence Berkeley National Laboratory institutional plan, FY 1996--2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The FY 1996--2001 Institutional Plan provides an overview of the Ernest Orlando Lawrence Berkeley National Laboratory mission, strategic plan, core business areas, critical success factors, and the resource requirements to fulfill its mission in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Laboratory Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Core Business Areas section identifies those initiatives that are potential new research programs representing major long-term opportunities for the Laboratory, and the resources required for their implementation. It also summarizes current programs and potential changes in research program activity, science and technology partnerships, and university and science education. The Critical Success Factors section reviews human resources; work force diversity; environment, safety, and health programs; management practices; site and facility needs; and communications and trust. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process. The plan identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office of Planning and Communications from information contributed by the Laboratory`s scientific and support divisions.

  14. Analysis, Design, and Evaluation of the UC-Berkeley Wave-Energy Extractor

    KAUST Repository

    Yeung, Ronald W.

    2010-01-01

    This paper evaluates the technical feasibility and performance characteristics of an ocean-wave energy to electrical energy conversion device that is based on a moving linear generator. The UC-Berkeley design consists of a cylindrical floater, acting as a rotor, which drives a stator consisting of two banks of wound coils. The performance of such a device in waves depends on the hydrodynamics of the floater, the motion of which is strongly coupled to the electromagnetic properties of the generator. Mathematical models are developed to reveal the critical hurdles that can affect the efficiency of the design. A working physical unit is also constructed. The linear generator is first tested in a dry environment to quantify its performance. The complete physical floater and generator system is then tested in a wave tank with a computer-controlled wavemaker. Measurements are compared with theoretical predictions to allow an assessment of the viability of the design and future directions for improvements. Copyright © 2010 by ASME.

  15. Design, Analysis, and Evaluation of the UC-Berkeley Wave-Energy Extractor

    KAUST Repository

    Yeung, Ronald W.

    2012-01-01

    This paper evaluates the technical feasibility and performance characteristics of an ocean-wave energy to electrical energy conversion device that is based on a moving linear generator. The UC-Berkeley design consists of a cylindrical floater, acting as a rotor, which drives a stator consisting of two banks of wound coils. The performance of such a device in waves depends on the hydrodynamics of the floater, the motion of which is strongly coupled to the electromagnetic properties of the generator. Mathematical models are developed to reveal the critical hurdles that can affect the efficiency of the design. A working physical unit is also constructed. The linear generator is first tested in a dry environment to quantify its performance. The complete physical floater and generator system is then tested in a wave tank with a computer-controlled wavemaker. Measurements are compared with theoretical predictions to allow an assessment of the viability of the design and the future directions for improvements. © 2012 American Society of Mechanical Engineers.

  16. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-10-01

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socio-economic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 70 CD-ROM diskettes (approximately 36 gigabytes) are on line via the Unix file server cedrcd. lbl. gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. Printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), or the UC Documents Library. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s).

  17. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-10-01

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socio-economic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 70 CD-ROM diskettes (approximately 36 gigabytes) are on line via the Unix file server cedrcd. lbl. gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. Printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), or the UC Documents Library. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user's application program(s).

  18. Development of an accelerator-based BNCT facility at the Berkeley Lab

    International Nuclear Information System (INIS)

    An accelerator-based BNCT facility is under construction at the Berkeley Lab. An electrostatic-quadrupole (ESQ) accelerator is under development for the production of neutrons via the 7Li(p,n)7Be reaction at proton energies between 2.3 and 2.5 MeV. A novel type of power supply, an air-core coupled transformer power supply, is being built for the acceleration of beam currents exceeding 50 mA. A metallic lithium target has been developed for handling such high beam currents. Moderator, reflector and neutron beam delimiter have extensively been modeled and designs have been identified which produce epithermal neutron spectra sharply peaked between 10 and 20 keV. These. neutron beams are predicted to deliver significantly higher doses to deep seated brain tumors, up to 50% more near the midline of the brain than is possible with currently available reactor beams. The accelerator neutron source will be suitable for future installation at hospitals

  19. O Amor na Internet: um Encontro Amoroso de um Adolescente

    Directory of Open Access Journals (Sweden)

    Márcia Stengel

    2015-12-01

    Full Text Available Neste artigo discutem-se as possibilidades que as redes sociais introduzem na vida amorosa de adolescentes. As novas tecnologias de comunicação influenciam a subjetividade, assim como mudam hábitos de vida e os modos de as pessoas se relacionarem, incluindo-se as relações amorosas. A adolescência é um momento decisivo na vida em que o sujeito procura estratégias para assegurar uma marca de identificação, sendo os amigos sua principal fonte para tal. A busca pelo parceiro amoroso é também fundamental, e as novas ofertas de instrumentos para tal devem impactar ações, pensamentos e imaginários. A partir do relato de caso publicado, trabalharam-se neste texto as conexões entre internet, adolescência e construção de relações amorosas. Observou-se que a iniciação afetivo-sexual pode ser facilitada pela internet, pois com ela os adolescentes podem dar maior vazão às fantasias e se sentir mais livres, destituídos das barreiras que dificultam as relações. Entretanto, também estão presentes desafios inerentes aos relacionamentos amorosos, sejam presenciais ou virtuais.

  20. Éter, espírito animal e causalidade no Siris de George Berkeley: uma visão imaterialista da analogia entre macrocosmo e microcosmo Ether, animal spirit and causality in George Berkeley’s Siris: an imaterialist vision of the analogy between macro and microcosmos

    Directory of Open Access Journals (Sweden)

    Silvia Alejandra Manzo

    2004-06-01

    Full Text Available A obra de Berkeley se desenvolveu como uma refutação do ceticismo e do ateísmo nos quais via uma ameaça à filosofia. No entanto, os seus interesses intelectuais não se limitaram a isso. Os temas científicos também integravam a agenda berkeleiana, nas diferentes obras onde se adverte que a metafísica penetra todos os rincões de sua especulação sobre a ciência. No Siris, uma obra peculiar dentro do corpus berkeleiano, as reflexões acerca do mundo natural são apresentadas em franca conexão com uma concepção metafísica geral. Berkeley desdobra ali uma visão da natureza próxima do neoplatonismo e do estoicismo, que culmina com um hino à filosofia antiga e neoplatônica. Nesse quadro são abordados diferentes aspectos filosóficos e científicos, entre outros, a analogia entre microcosmo e macrocosmo, que se apresenta como uma realidade indiscutível. Berkeley entende que esse vínculo entre o homem e o mundo é possível mediante o éter, uma entidade à qual confere características muito especiais. O objetivo deste trabalho é expor a maneira como Berkeley concebe essa analogia partindo da tradição filosófica e das teorias científicas de seu tempo e ligando-a à imagem moderna do mundo.Berkeley's thought was developed as a refusal of materialism and skepticism that in his opinion menaced philosophy. However, his intellectual interests were not confined to this aim. Scientific topics were also included in Berkeley's agenda. In the works concerned with scientific issues, the omnipresence of his metaphysics is to be found. In Siris, a peculiar work in the Berkelian corpus, reflexions about the natural world are exhibited in explicit link with a metaphysical frame. Berkeley exposes a view of nature akin to neoplatonism and stoicism and ends his work with an anthem in honor of ancient and neoplatonic philosophy. Several scientific topics are dealt with, such as the analogy between macrocosm and microcosm, that it is exposed as

  1. Um problema de teoria de grafos

    OpenAIRE

    Barbedo, Inês; Pacheco, Maria F.

    2005-01-01

    Uma etapa fulcral da resolução de um problema é a sua representação por um diagrama. Um grafo pode ser a ferramenta ideal para a esquematização de uma situação, podendo representar redes físicas (redes viárias, circuitos eléctricos) assim como as interacções que ocorrem entre indivíduos num ecossistema ou numa teia de relações sociais. Sendo os conceitos introdutórios da Teoria de Grafos de fácil compreensão mesmo por alunos numa fase inicial da sua formação, ela é um tópico motivador e um a...

  2. Compte rendu de : Luc Peterschmitt, Berkeley et la chimie. Une philosophie pour la chimie au XVIIIe siècle

    Directory of Open Access Journals (Sweden)

    François Pépin

    2012-03-01

    Full Text Available Ce livre, issu d’une thèse de doctorat sur Berkeley et les sciences, constitue la première étude systématique des rapports entre Berkeley et la chimie. C’est aussi une tentative originale pour examiner la cohérence et la pertinence d’un des derniers textes de Berkeley, la Siris, souvent considérée comme un ouvrage mineur, voire comme une erreur de vieillesse. Ces deux projets novateurs se croisent, puisque c’est par la philosophie de la chimie que Luc Peterschmitt cherche à montrer l’intérêt ...

  3. Bullying na Escola: um sofrimento

    Directory of Open Access Journals (Sweden)

    Marlene Silva Sardinha Gurpilhares

    2014-07-01

    Full Text Available O bullying é uma forma de violência presente nas escolas e o termo é utilizado para caracterizar todas as formas de agressões repetitivas psicológicas e físicas, direta ou indiretamente. Esta violência causa sofrimentos, intimidação e medo, sempre numa relação de poder entre pares. Esta pesquisa trata de um estudo do bullying escolar: o que é, como surgiu, como identificá-lo e sua caracterização, conseqüências, causas, o papel da escola, de professores e pais e uma proposta prática que pode ser adotada para sua prevenção e contenção. O objetivo é organizar materiais para leitura dos atores educacionais para uma possível reflexão, através de pesquisas bibliográficas. Esta violência é grave e deveria ser tratada como saúde pública, devido às conseqüências que traz, como queda na aprendizagem, na autoestima e em casos mais graves, até o suicido e outras tragédias. A escola necessita atentar para esse tipo de violência, revendo suas ações em todos os momentos, tendo um olhar integral e diferenciado em relação aos alunos. É fundamental que o bullying não seja tratado como brincadeira de criança e para ser identificado e combatido é necessária uma ação entre a família e todos da escola, que pode ser desenvolvida através de projetos que ajudem a apontar caminhos para a solução do problema. Tais ações devem ser pautadas por constantes debates e reflexões, nas quais o aluno se torne o protagonista. Não existem fórmulas prontas, pois a intervenção deve ser feita através da realidade de cada escola.

  4. Control system for the 2nd generation Berkeley automounters (BAM2) at GM/CA-CAT macromolecular crystallography beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Makarov, O., E-mail: makarov@anl.gov [GM/CA-CAT, Biosciences Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Hilgart, M.; Ogata, C.; Pothineni, S. [GM/CA-CAT, Biosciences Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Cork, C. [Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States)

    2011-09-01

    GM/CA-CAT at Sector 23 of the Advanced Photon Source (APS) is an NIH funded facility for crystallographic structure determination of biological macromolecules by X-ray diffraction. A second-generation Berkeley automounter is being integrated into the beamline control system at the 23BM experimental station. This new device replaces the previous all-pneumatic gripper motions with a combination of pneumatics and XYZ motorized linear stages. The latter adds a higher degree of flexibility to the robot including auto-alignment capability, accommodation of a larger capacity sample Dewar of arbitrary shape, and support for advanced operations such as crystal washing, while preserving the overall simplicity and efficiency of the Berkeley automounter design.

  5. Guidelines for generators to meet HWHF acceptance requirements for hazardous, radioactive, and mixed wastes at Berkeley Lab. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Albert, R.

    1996-06-01

    This document provides performance standards that one, as a generator of hazardous chemical, radioactive, or mixed wastes at the Berkeley Lab, must meet to manage their waste to protect Berkeley Lab staff and the environment, comply with waste regulations and ensure the continued safe operation of the workplace, have the waste transferred to the correct Waste Handling Facility, and enable the Environment, Health and Safety (EH and S) Division to properly pick up, manage, and ultimately send the waste off site for recycling, treatment, or disposal. If one uses and generates any of these wastes, one must establish a Satellite Accumulation Area and follow the guidelines in the appropriate section of this document. Topics include minimization of wastes, characterization of the wastes, containers, segregation, labeling, empty containers, and spill cleanup and reporting.

  6. Transportation Periodicals And Newsletters Currently Received At The Institute Of Transportation Studies Library, University Of California At Berkeley

    OpenAIRE

    Hernandez, Paul A.

    2000-01-01

    This publication is intended to serve as a convenient reference to selected transportation periodicals and newsletters currently (2000) received by UC Berkeley's Harmer E. Davis Transportation Li-brary. This latest version of Transportation Periodicals and Newsletters represents a thourough revision of earlier editions (1989, 1993, and 1995) published under the same (or similar) title. The subject content of this listing reflects the subject strengths of the H.E. Davis Transportation Library:...

  7. A simple grid implementation with Berkeley Open Infrastructure for Network Computing using BLAST as a model.

    Science.gov (United States)

    Pinthong, Watthanai; Muangruen, Panya; Suriyaphol, Prapat; Mairiang, Dumrong

    2016-01-01

    Development of high-throughput technologies, such as Next-generation sequencing, allows thousands of experiments to be performed simultaneously while reducing resource requirement. Consequently, a massive amount of experiment data is now rapidly generated. Nevertheless, the data are not readily usable or meaningful until they are further analysed and interpreted. Due to the size of the data, a high performance computer (HPC) is required for the analysis and interpretation. However, the HPC is expensive and difficult to access. Other means were developed to allow researchers to acquire the power of HPC without a need to purchase and maintain one such as cloud computing services and grid computing system. In this study, we implemented grid computing in a computer training center environment using Berkeley Open Infrastructure for Network Computing (BOINC) as a job distributor and data manager combining all desktop computers to virtualize the HPC. Fifty desktop computers were used for setting up a grid system during the off-hours. In order to test the performance of the grid system, we adapted the Basic Local Alignment Search Tools (BLAST) to the BOINC system. Sequencing results from Illumina platform were aligned to the human genome database by BLAST on the grid system. The result and processing time were compared to those from a single desktop computer and HPC. The estimated durations of BLAST analysis for 4 million sequence reads on a desktop PC, HPC and the grid system were 568, 24 and 5 days, respectively. Thus, the grid implementation of BLAST by BOINC is an efficient alternative to the HPC for sequence alignment. The grid implementation by BOINC also helped tap unused computing resources during the off-hours and could be easily modified for other available bioinformatics software.

  8. A simple grid implementation with Berkeley Open Infrastructure for Network Computing using BLAST as a model.

    Science.gov (United States)

    Pinthong, Watthanai; Muangruen, Panya; Suriyaphol, Prapat; Mairiang, Dumrong

    2016-01-01

    Development of high-throughput technologies, such as Next-generation sequencing, allows thousands of experiments to be performed simultaneously while reducing resource requirement. Consequently, a massive amount of experiment data is now rapidly generated. Nevertheless, the data are not readily usable or meaningful until they are further analysed and interpreted. Due to the size of the data, a high performance computer (HPC) is required for the analysis and interpretation. However, the HPC is expensive and difficult to access. Other means were developed to allow researchers to acquire the power of HPC without a need to purchase and maintain one such as cloud computing services and grid computing system. In this study, we implemented grid computing in a computer training center environment using Berkeley Open Infrastructure for Network Computing (BOINC) as a job distributor and data manager combining all desktop computers to virtualize the HPC. Fifty desktop computers were used for setting up a grid system during the off-hours. In order to test the performance of the grid system, we adapted the Basic Local Alignment Search Tools (BLAST) to the BOINC system. Sequencing results from Illumina platform were aligned to the human genome database by BLAST on the grid system. The result and processing time were compared to those from a single desktop computer and HPC. The estimated durations of BLAST analysis for 4 million sequence reads on a desktop PC, HPC and the grid system were 568, 24 and 5 days, respectively. Thus, the grid implementation of BLAST by BOINC is an efficient alternative to the HPC for sequence alignment. The grid implementation by BOINC also helped tap unused computing resources during the off-hours and could be easily modified for other available bioinformatics software. PMID:27547555

  9. Do buzz ao marketing viral : um estudo

    OpenAIRE

    Viveiros, Nuno Filipe Carvalho

    2015-01-01

    Dissertação de Mestrado em Gestão de Empresas/MBA. Com o crescente ênfase do marketing viral e das redes sociais na divulgação de produtos, serviços e marcas, o seu estudo torna-se pertinente para o desenvolvimento de campanhas mais eficazes e eficientes. Esta tese apresenta um estudo centralizado sobre o impacto que um país tem na criação de buzz de modo a tornar as campanhas de marketing, virais. Estudando e analisando três países (dois desenvolvidos e um em desenvolvimento), com o objet...

  10. NATUROLOGIA: UM DIÁLOGO ENTRE SABERES

    OpenAIRE

    Silva, Adriana Elias Magno da

    2013-01-01

    A Naturologia é um conhecimento caracterizado pela mescla de racionalidadesmédicas, de filosofias e de técnicas de cura orientais, ocidentais, modernas e tradicionais. É um fenômeno decorrente da crise de paradigmas do mundo contemporâneo e da necessidade de revisão e ampliação dos modelos de prática médica vigentes. Apresenta-se como um conhecimento transdisciplinar filiado a modelos integrativos e complementares de atuação e atenção em saúde. Esta pesquisa analisou o processo de estruturaçã...

  11. Um sanitarista chamado Walter Leser

    Directory of Open Access Journals (Sweden)

    Guilherme Arantes Mello

    2015-09-01

    Full Text Available ResumoFaz uma breve revisão da trajetória profissional do médico sanitarista Walter Sidney Pereira Leser, falecido em 2004 aos 94 anos. Autodidata, a partir de sua tese de doutoramento de 1933, torna-se referência no campo da estatística e epidemiologia no país, com dezenas de estudos e orientações. No campo clínico é um dos fundadores do Laboratório Fleury, e participa da criação do CREMESP. Como acadêmico, foi catedrático da Escola de Sociologia e Política de São Paulo, Escola Paulista de Medicina e Faculdade de Farmácia e Odontologia da USP. Introduziu os testes objetivos no exame vestibular, e esteve à frente da criação do CESCEM e Fundação Carlos Chagas. Na Escola Paulista criou o primeiro Departamento de Medicina Preventiva do país. Como administrador público, foi secretário de Estado da Saúde entre 1967 e 1971 e entre 1975 e 1979, responsável por extensas reformas e inovações. Entre as mais lembradas, a criação da carreira de médico sanitarista. Por todo esse legado, emprestou seu nome à “Medalha de Honra e Mérito da Gestão Pública em Saúde” do governo paulista.

  12. Brief History of Herpetology in the Museum of Vertebrate Zoology, University of California, Berkeley, with a List of Type Specimens of Recent Amphibians and Reptiles

    OpenAIRE

    Rodríguez-Robles, Javier A; Good, David A; Wake, David B

    2003-01-01

    An overview of the herpetological program of the Museum of Vertebrate Zoology (MVZ), University of California, Berkeley, is presented. The history of herpetological activities in the MVZ and more generally at Berkeley is summarized. Although the MVZ has existed since 1908, until 1945 there was no formal curator for the collection of amphibians and nonavian reptiles. Since that time Robert C. Stebbins, David B. Wake, Harry W. Greene, Javier A. Rodríguez-Robles (in an interim capacity), and Cra...

  13. Nonlinear magnetohydrodynamics of edge localized mode precursors

    International Nuclear Information System (INIS)

    A possible origin of edge-localized-mode (ELM) precursors based on nonlinear ideal peeling-ballooning mode is reported. Via nonlinear variational principle, a nonlinear evolution equation of the radial displacement is derived and solved, analytically. Besides an explosive growth in the initial nonlinear phase, it is found that the local displacement evolves into an oscillating state in the developed nonlinear phase. The nonlinear frequency of the ELM precursors scales as ωpre∼x1/3ξ^ψ,in2/3n, with x position in radial direction, ξ^ψ,in strength of initial perturbation, and n toroidal mode number

  14. UM TRATADO PARA O AMOR

    Directory of Open Access Journals (Sweden)

    Maria José Caldeira do Amaral

    2015-07-01

    Full Text Available No Tratado do Amor Cortês - Tractatus de Amore - André Capelão deseja oferecer ao leitor a arte cortês de amar, a beleza do desejo erótico e a disciplina da paixão constitutiva dessa arte que é amar. O maior argumento dessa obra é efetivar o suspiro fundo que a dimensão amorosa infunde na alma do homem e da mulher aos quais foi concedida a virtude. Para esse autor, escriba da chancelaria real e talvez, não se sabe com certeza, um Ordo Sacratus, o amor é a raiz de toda cortesia, a fonte de todo bem. Nosso objetivo, então, é encontrar nessa suma amorosa construída nos enlaces da Literatura de Cavalaria Medieval, os desdobramentos essenciais dessa vida afetiva bela e virtuosa no enredo profundo do qual emerge o afeto, a fé e a contradição da experiência humana do sofrimento amoroso. Palavras Chave: Literatura Medieval. Amor Cortês, André Capelão, virtude, desejo. Abstract: With the treaty toward the love - Tractatus de Amore – André Capelão offers to the reader the courteous’ art for love, the erotic desire’s beauty and the  suffering discipline belong this love’s art  is. The best reason of this literary composition is to achieve the depth sigh that the loving dimension infuses into the lovers’s soul, the man and the woman wich this virtue was conceded. For this author, the royal chancery scribe and perhaps, no one knows for sure, a Sacratus Ordo, love is the root of all free, the source of all good. Our goal, then, is to find this sum loving built in interlacing of Medieval Knights literature, the essential developments of this beautiful and virtuous love life in the deep storyline which emerges affection, faith and the contradiction of the human experience of love suffering. Key words: Medieval Literature. Courteous Love. André Capelão. Virtue.

  15. Target Selection and Deselection at the Berkeley StructuralGenomics Center

    Energy Technology Data Exchange (ETDEWEB)

    Chandonia, John-Marc; Kim, Sung-Hou; Brenner, Steven E.

    2005-03-22

    At the Berkeley Structural Genomics Center (BSGC), our goalis to obtain a near-complete structural complement of proteins in theminimal organisms Mycoplasma genitalium and M. pneumoniae, two closelyrelated pathogens. Current targets for structure determination have beenselected in six major stages, starting with those predicted to be mosttractable to high throughput study and likely to yield new structuralinformation. We report on the process used to select these proteins, aswell as our target deselection procedure. Target deselection reducesexperimental effort by eliminating targets similar to those recentlysolved by the structural biology community or other centers. We measurethe impact of the 69 structures solved at the BSGC as of July 2004 onstructure prediction coverage of the M. pneumoniae and M. genitaliumproteomes. The number of Mycoplasma proteins for which thefold couldfirst be reliably assigned based on structures solved at the BSGC (24 M.pneumoniae and 21 M. genitalium) is approximately 25 percent of the totalresulting from work at all structural genomics centers and the worldwidestructural biology community (94 M. pneumoniae and 86M. genitalium)during the same period. As the number of structures contributed by theBSGC during that period is less than 1 percent of the total worldwideoutput, the benefits of a focused target selection strategy are apparent.If the structures of all current targets were solved, the percentage ofM. pneumoniae proteins for which folds could be reliably assigned wouldincrease from approximately 57 percent (391 of 687) at present to around80 percent (550 of 687), and the percentage of the proteome that could beaccurately modeled would increase from around 37 percent (254 of 687) toabout 64 percent (438 of 687). In M. genitalium, the percentage of theproteome that could be structurally annotated based on structures of ourremaining targets would rise from 72 percent (348 of 486) to around 76percent (371 of 486), with the

  16. Heavy ion facilities and heavy ion research at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1973-10-01

    Lawrence Berkeley Laboratory has been heavily involved since 1956 in the construction and adaptation of particle accelerators for the acceleration of heavy ions. At the present time it has the most extensive group of accelerators with heavy-ion capability in the United States: The SuperHILAC, the 88-Inch Cyclotron, and the Bevatron/Bevalac. An extensive heavy-ion program in nuclear and particle physics, in nuclear chemistry, and in the study of biological effects of heavy-ion irradiations has been supported in the past; and the Laboratory has a strong interest in expanding both its capabilities for heavy-ion acceleration and its participation in heavy-ion science. The first heavy-ion accelerator at LBL was the HILAC, which began operation in 1957. A vigorous program of research with ion beams of masses 4 through 40 began at that time and continued until the machine was shut down for modifications in February 1971. At that time, a grant of $3 M had been received from the AEC for a total reconstruction of the HILAC, to turn it into an upgraded accelerator, the SuperHILAC. This new machine is designed for the acceleration of all ions through uranium to an energy of 8.5 MeV/u. The SuperHILAC is equipped with two injectors. The lower energy injector, a 750-kV Cockcroft-Walton machine, was put into service in late 1972 for acceleration of ions up through {sup 40}Ar. By spring of 1973, operation of the SuperHILAC with this injector exceeded the performance of the original HILAC. The second injector, a 2.5-MV Dynamitron, was originally designed for the Omnitron project and built with $1 M of Omnitron R and D funds. Commissioning of this injector began in 1973 and proceeded to the point where nanoampere beams of krypton were available for a series of research studies in May and June. The first publishable new results with beams heavier than {sup 40}Ar were obtained at that time. Debugging and injector improvement projects will continue in FY 74.

  17. Analysis of background distributions of metals in the soil at Lawrence Berkeley National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, David; Baskin, David; Brown, Dennis; Lund, Loren; Najita, Julie; Javandel, Iraj

    2009-03-15

    As part of its Resource Conservation and Recovery Act (RCRA) Corrective Action Program (CAP), the Lawrence Berkeley National Laboratory (LBNL) Environmental Restoration Program conducted an evaluation of naturally occurring metals in soils at the facility. The purpose of the evaluation was to provide a basis for determining if soils at specific locations contained elevated concentrations of metals relative to ambient conditions. Ambient conditions (sometimes referred to as 'local background') are defined as concentrations of metals in the vicinity of a site, but which are unaffected by site-related activities (Cal-EPA 1997). Local background concentrations of 17 metals were initially estimated by LBNL using data from 498 soil samples collected from borings made during the construction of 71 groundwater monitoring wells (LBNL 1995). These concentration values were estimated using the United States Environmental Protection Agency's (USEPA's) guidance that was available at that time (USEPA 1989). Since that time, many more soil samples were collected and analyzed for metals by the Environmental Restoration Program. In addition, the California Environmental Protection Agency (Cal-EPA) subsequently published a recommended approach for calculating background concentrations of metals at hazardous waste sites and permitted facilities (Cal-EPA 1997). This more recent approach differs from that recommended by the USEPA and used initially by LBNL (LBNL 2002). The purpose of the 2002 report was to apply the recommended Cal-EPA procedure to the expanded data set for metals that was available at LBNL. This revision to the 2002 report has been updated to include more rigorous tests of normality, revisions to the statistical methods used for some metals based on the results of the normality tests, and consideration of the depth-dependence of some sample results. As a result of these modifications, estimated background concentrations for some metals have been

  18. Targeting bactoprenol-coupled cell envelope precursors.

    Science.gov (United States)

    Ulm, Hannah; Schneider, Tanja

    2016-09-01

    Targeting the bactoprenol-coupled cell wall precursor lipid II is a validated antibacterial strategy. In this review, selected prototype lipid II-binding antibiotics of different chemical classes are discussed. Although these compounds attack the same molecular target, they trigger nuanced and diverse cellular effects. Consequently, the mechanisms of antibacterial resistance and the likelihood of resistance development may vary substantially. PMID:27495122

  19. PRECURSORS OF EARTHQUAKES: VLF SIGNALSIONOSPHERE IONOSPHERE RELATION

    OpenAIRE

    Mustafa ULAS; ATA, Fikret; Hasan Hüseyin BALIK

    2013-01-01

    lot of people have died because of earthquakes every year. Therefore It is crucial to predict the time of the earthquakes reasonable time before it had happed. This paper presents recent information published in the literature about precursors of earthquakes. The relationships between earthquakes and ionosphere are targeted to guide new researches in order to study further to find novel prediction methods.

  20. Validity and Reliability of Preschool, First and Second Grade Versions of Berkeley Parenting Self-Efficacy Scale

    Directory of Open Access Journals (Sweden)

    Shahrbanoo Tajeri

    2009-02-01

    Full Text Available "nObjective: The purpose of this study is to examine the factor structure, internal consistency, and construct validity of preschool, first and second grade versions of Berkeley Parenting self-efficacy scale. "nMethod:  The subjects were 317 mothers: (102 mothers of preschool children, 111 mothers of first grade children and 104 mothers of second grade children who were randomly selected from schools in Tehran. They completed Berkeley parenting self-efficacy and Rotter `s locus of control scales. Factor analysis using the principle component method was used to identify the factor structure of parenting self-efficacy scale. Cronbach`s alpha coefficient was used to identify the reliability of parenting self efficacy scale. "nResults: Results of this study indicated that the cronbach`s alpha coefficient was 0.84, 0.87, 0.64 for preschool, first grade and second grade versions respectively. Based on the scree test ,,factor analysis produced two factors of maternal strategy and child outcome, and it also produced the highest level of total variance explained by these 2 factors. The Parenting self-efficacy scale was negatively associated with measure of locus of control(r=-0.54 for the preschool version, -0.64 for the first grade version and -0.54 for the second grade version. "nConclusion: Due to relatively high reliability and validity of preschool, first and second grade versions of Berkeley Parenting Self-Efficacy scale, this scale could be used as a reliable and valid scale in other research areas

  1. Results of a monitoring programme in the environs of Berkeley aimed at collecting Chernobyl data for foodchain model validation

    International Nuclear Information System (INIS)

    The results of a fallout measurement programme which was carried out in the environs of Berkeley Nuclear Laboratory in the United Kingdom following the Chernobyl reactor accident in April 1986 are presented in this report. The programme was aimed at establishing a time-dependent data base of concentrations of Chernobyl fallout radionuclides in selected agricultural products. Results were obtained for milk, grass, silage, soil and wheat over an eighteen month period from May 1986. It is intended to use the data to validate the CEGB's dynamic foodchain model, which is incorporated in the FOODWEB module of the NECTAR environmental code. (author)

  2. Berkeley Supernova Ia Program I: Observations, Data Reduction, and Spectroscopic Sample of 582 Low-Redshift Type Ia Supernovae

    OpenAIRE

    Silverman, Jeffrey M.; Foley, Ryan J.; Filippenko, Alexei V.; Ganeshalingam, Mohan; Barth, Aaron J.; Chornock, Ryan; Griffith, Christopher V.; Kong, Jason J.; Lee, Nicholas; Leonard, Douglas C.; Matheson, Thomas; Miller, Emily G.; Steele, Thea N.; Barris, Brian J.; Bloom, Joshua S.

    2012-01-01

    In this first paper in a series we present 1298 low-redshift (z\\leq0.2) optical spectra of 582 Type Ia supernovae (SNe Ia) observed from 1989 through 2008 as part of the Berkeley SN Ia Program (BSNIP). 584 spectra of 199 SNe Ia have well-calibrated light curves with measured distance moduli, and many of the spectra have been corrected for host-galaxy contamination. Most of the data were obtained using the Kast double spectrograph mounted on the Shane 3 m telescope at Lick Observatory and have...

  3. Adolfo Celi, um olhar para dois mundos

    Directory of Open Access Journals (Sweden)

    Alessandra Vanucci

    2002-11-01

    Full Text Available O ensaio resgata a vivência brasileira de Adolfo Celi, ator e diretor italiano ativo em cinema e teatro (1922-1986, inserido no laboratório paulista da renovação, na década de 1950. Sua atuação impôs, no palco, o legado texto-cêntrico de Sílvio d'Amico e a utopia do ator plástico de Copeau e, na tela, a estética neo-realista associada a uma atuação fortemente marcada pelo ideário teatral moderno. As intuições, a herança, as oportunidades e as invenções perdidas desta experiência transcultural sugerem um quadro de realização somente parcial do projeto modernizador. Ao entrar na década de 60, é a sensação de ter esgotado um ciclo existencial que fornece a Celi um válido álibi para o retorno. Álibi (1969, seu terceiro e último filme como diretor, realizado na Itália com Gassmann e Lucignani, é um testemunho de vida e memórias, de raiva e de saudade do Brasil; e um precioso guia para entender sua extraordinária ‘aventura americana’.

  4. Um novo paradigma para uma nova antropologia

    Directory of Open Access Journals (Sweden)

    Susin, Luiz Carlos

    2007-01-01

    Full Text Available Este artigo recolhe relativas à identidade humana no contexto das pesquisas científicas e das transformações ocorridas nos últimos tempos, especialmente no século XX. A nova fisica, com um novo desenho do universo, uma nova cosmologia, radicaliza, por um lado, as questões em torno do humano, e, por outro lado, abre novas possibilidades. Um novo paradigma , mais holístico, incluindo a dimensão ecológica, ou ao menos com cenários mais adequados, pode ser vislumbrado, embora ainda não descrito, por estarmos numa "era de transição". Na parte que nos toca no universo - a terra - o futuro da vida depende, em grande parte, de decisões éticas que somente o ser humano é convocado a assumir

  5. Electromagnetic Whistler Precursors at Supercritical Interplanetary Shocks

    Science.gov (United States)

    Wilson, L. B., III

    2012-01-01

    We present observations of electromagnetic precursor waves, identified as whistler mode waves, at supercritical interplanetary shocks using the Wind search coil magnetometer. The precursors propagate obliquely with respect to the local magnetic field, shock normal vector, solar wind velocity, and they are not phase standing structures. All are right-hand polarized with respect to the magnetic field (spacecraft frame), and all but one are right-hand polarized with respect to the shock normal vector in the normal incidence frame. Particle distributions show signatures of specularly reflected gyrating ions, which may be a source of free energy for the observed modes. In one event, we simultaneously observe perpendicular ion heating and parallel electron acceleration, consistent with wave heating/acceleration due to these waves.

  6. [Presentation of the Lunar Precursor Robotics Program

    Science.gov (United States)

    Lavoie, Anthony R.

    2008-01-01

    The Lunar Precursor Robotics Program (LPRP) is the host program for the Exploration Systems Mission Directorate's (ESMD) lunar robotic precursor missions to the Moon. The program includes two missions, the Lunar Reconnaissance Orbiter (LRO), and the Lunar CRater Observation and Sensing Satellite (LCROSS). Both missions will provide the required lunar information to support development and operations of those systems required for Human lunar return. LPRP is developing a lunar mapping plan, Called the Lunar Mapping and Modeling Project, to create the capability to archive and present all data from LRO, LCROSS, historical lunar missions, and international lunar missions for future mission planning and operations. LPRP is also developing its educational and public outreach activities for the Vision for Space Exploration's first missions. LPRP is working closely with the Science Mission Directorate as their lunar activities come into focus.

  7. Um palimpsesto impossível

    Directory of Open Access Journals (Sweden)

    Dilma Castelo Branco Diniz

    2007-06-01

    Full Text Available Este estudo trata da questão do exílio em Le figuier enchanté, de Marco Micone, um escritor italiano imigrante no Quebec. O autor revela a problemática da adaptação em outro país, através de uma visão ao mesmo tempo pessoal e coletiva, mostrando que a cultura do imigrante é sempre híbrida, um palimpsesto impossível.

  8. Proinsulin: from hormonal precursor to neuroprotective factor

    OpenAIRE

    Flora de Pablo

    2011-01-01

    In the last decade, non-canonical functions have been described for several molecules with hormone-like activities in different stages of vertebrate development. Since its purification in the 1960s, proinsulin has been one of the best described hormonal precursors, though it has been overwhelmingly studied in the context of insulin, the mature protein secreted by the pancreas. Beginning with our discovery of the presence and precise regulation of proinsulin mRNA in early neurulation and neuro...

  9. Proinsulin: From Hormonal Precursor to Neuroprotective Factor

    OpenAIRE

    De La Rosa, Enrique J; Pablo, Flora de

    2011-01-01

    In the last decade, non-canonical functions have been described for several molecules with hormone-like activities in different stages of vertebrate development. Since its purification in the 1960s, proinsulin has been one of the best described hormonal precursors, though it has been overwhelmingly studied in the context of insulin, the mature protein secreted by the pancreas. Beginning with our discovery of the presence and precise regulation of proinsulin mRNA in early neurulation and neuro...

  10. Molecular imaging in myeloma precursor disease

    OpenAIRE

    Mena, E.; Choyke, P; Tan, E; Landgren, O; Kurdziel, K

    2011-01-01

    Multiple myeloma (MM) is consistently preceded by its pre-malignant states, monoclonal gammopathy of undetermined significance (MGUS) and/or smoldering multiple myeloma (SMM). By definition, precursor conditions do not exhibit end-organ disease (anemia, hypercalcemia, renal failure, skeletal lytic lesions, or a combination of these). However, new imaging methods are demonstrating that some patients in the MGUS or SNM category are exhibiting early signs of MM.

  11. PRECURSORS OF EARTHQUAKES: VLF SIGNALSIONOSPHERE IONOSPHERE RELATION

    Directory of Open Access Journals (Sweden)

    Mustafa ULAS

    2013-01-01

    Full Text Available lot of people have died because of earthquakes every year. Therefore It is crucial to predict the time of the earthquakes reasonable time before it had happed. This paper presents recent information published in the literature about precursors of earthquakes. The relationships between earthquakes and ionosphere are targeted to guide new researches in order to study further to find novel prediction methods.

  12. Cellular Kinetics of Perivascular MSC Precursors

    Directory of Open Access Journals (Sweden)

    William C. W. Chen

    2013-01-01

    Full Text Available Mesenchymal stem/stromal cells (MSCs and MSC-like multipotent stem/progenitor cells have been widely investigated for regenerative medicine and deemed promising in clinical applications. In order to further improve MSC-based stem cell therapeutics, it is important to understand the cellular kinetics and functional roles of MSCs in the dynamic regenerative processes. However, due to the heterogeneous nature of typical MSC cultures, their native identity and anatomical localization in the body have remained unclear, making it difficult to decipher the existence of distinct cell subsets within the MSC entity. Recent studies have shown that several blood-vessel-derived precursor cell populations, purified by flow cytometry from multiple human organs, give rise to bona fide MSCs, suggesting that the vasculature serves as a systemic reservoir of MSC-like stem/progenitor cells. Using individually purified MSC-like precursor cell subsets, we and other researchers have been able to investigate the differential phenotypes and regenerative capacities of these contributing cellular constituents in the MSC pool. In this review, we will discuss the identification and characterization of perivascular MSC precursors, including pericytes and adventitial cells, and focus on their cellular kinetics: cell adhesion, migration, engraftment, homing, and intercellular cross-talk during tissue repair and regeneration.

  13. Ionospheric precursors for crustal earthquakes in Italy

    Science.gov (United States)

    Perrone, L.; Korsunova, L. P.; Mikhailov, A. V.

    2010-04-01

    Crustal earthquakes with magnitude 6.0>M≥5.5 observed in Italy for the period 1979-2009 including the last one at L'Aquila on 6 April 2009 were considered to check if the earlier obtained relationships for ionospheric precursors for strong Japanese earthquakes are valid for the Italian moderate earthquakes. The ionospheric precursors are based on the observed variations of the sporadic E-layer parameters (h'Es, fbEs) and foF2 at the ionospheric station Rome. Empirical dependencies for the seismo-ionospheric disturbances relating the earthquake magnitude and the epicenter distance are obtained and they have been shown to be similar to those obtained earlier for Japanese earthquakes. The dependences indicate the process of spreading the disturbance from the epicenter towards periphery during the earthquake preparation process. Large lead times for the precursor occurrence (up to 34 days for M=5.8-5.9) tells about a prolong preparation period. A possibility of using the obtained relationships for the earthquakes prediction is discussed.

  14. Disinfection byproduct formation from lignin precursors.

    Science.gov (United States)

    Hua, Guanghui; Kim, Junsung; Reckhow, David A

    2014-10-15

    Lignin is the most abundant aromatic plant component in terrestrial ecosystems. This study was conducted to determine the contribution of lignin residues in natural water to the formation of disinfection byproducts (DBPs) in drinking water. We investigated the formation of different classes of DBPs from lignin model compounds, lignin polymers, and humic substances using two common disinfection techniques, chlorination and chloramination. The contributions of lignin to the overall formation of DBPs from these organic products were determined based on the observed abundances of individual lignin phenols and their DBP yields. Model lignin phenols generally produced higher trichloroacetic acid (TCAA) yields than chloroform and dichloroacetic acid (DCAA) during chlorination. Lignin phenols generally produced higher DBP yields but lower percentages of unknown total organic halogen compared to bulk humic substances and lignin polymers. The relative significance of lignin phenols as chlorination DBP precursors generally follows the order of TCAA > DCAA&chloroform. The relative significance of lignin phenols to DBP formation by chloramination follows the order: TCAA > DCAA&DCAN > chloroform. Overall, lignin phenols are more important as TCAA precursors than as chloroform and DCAA precursors.

  15. Ionospheric precursors for crustal earthquakes in Italy

    Directory of Open Access Journals (Sweden)

    L. Perrone

    2010-04-01

    Full Text Available Crustal earthquakes with magnitude 6.0>M≥5.5 observed in Italy for the period 1979–2009 including the last one at L'Aquila on 6 April 2009 were considered to check if the earlier obtained relationships for ionospheric precursors for strong Japanese earthquakes are valid for the Italian moderate earthquakes. The ionospheric precursors are based on the observed variations of the sporadic E-layer parameters (h'Es, fbEs and foF2 at the ionospheric station Rome. Empirical dependencies for the seismo-ionospheric disturbances relating the earthquake magnitude and the epicenter distance are obtained and they have been shown to be similar to those obtained earlier for Japanese earthquakes. The dependences indicate the process of spreading the disturbance from the epicenter towards periphery during the earthquake preparation process. Large lead times for the precursor occurrence (up to 34 days for M=5.8–5.9 tells about a prolong preparation period. A possibility of using the obtained relationships for the earthquakes prediction is discussed.

  16. Mielose eritrêmica em um gato Erythremic myelosis in a cat

    Directory of Open Access Journals (Sweden)

    Danieli Brolo Martins

    2011-01-01

    Full Text Available Neste relato, é descrito um caso de mielose eritrêmica em um gato. Essa doença é considerada de aparecimento raro na clínica médica veterinária. Uma gata, raça Siamês, de um ano de idade, foi atendida com sinais clínicos de acentuada anemia, emaciação e febre. Havia marcada anemia arregenerativa, com grande número de precursores eritróides e megaloblastos atípicos, identificados pelo hemograma. O mielograma revelou população eritrocitária acima de 85%, quando comparada com a mielóide. A citologia aspirativa por agulha fina dos linfonodos revelou a presença de células eritróides imaturas. Na necropsia, o baço, os linfonodos e a medula óssea estavam obliterados por células neoplásicas. O diagnóstico de mielose eritrêmica foi dado com base nos achados clínico-laboratoriais e anatomopatológicos.The aim of this research is to describe a case of erythremic myelosis in a cat. This disease is considered rare in veterinary clinics. A one-year-old female siamese cat was brought to the veterinary hospital with clinical signs of severe anemia, emaciation and fever. The blood panel revealed marked nonregenerative anemia with elevated number of atypical erythroid progenitors and megacaryoblasts. Elevated atypical erythroid over myeloid precursors (above 85% were also found in bone marrow biopsy. Fine-needle aspiration cytology of lymph nodes revealed immature erythoid cells. At necropsy, spleen, lymph nodes and bone marrow were obliterated by neoplastic cells. The diagnosis of erythremic myelosis was given by clinical, laboratorial and pathological findings.

  17. Um olhar, uma sentença

    Directory of Open Access Journals (Sweden)

    Sérgio Medeiros

    2003-12-01

    Full Text Available Em seu conto “La escritura del dios”, o escritor argentino Jorge Luis Borges descreve uma visão mística de um sacerdote maia que redescobre suas raízes religiosas nativas. O artigo discute a natureza de sua experiência mística.

  18. The metallicities of UM151, UM408 and A1228+12 revisited

    CERN Document Server

    Pustilnik, S A; Masegosa, J; Márquez, I; Pramsky, A G; Ugryumov, A V; S.A., Pustilnik; A.Y., Kniazev; J., Masegosa; I., Marquez

    2002-01-01

    We present the results of new spectrophotometry and heavy element abundance determinations for 3 dwarf galaxies UM151, UM408 and A1228+12 (RMB132). These galaxies have been claimed in the literature to have very low metallicities, corresponding to log(O/H)+12 < 7.65, that are in the metallicity range of some candidate local young galaxies. We present higher S/N data for these three galaxies. UM151 and UM408 have significantly larger metallicities: log(O/H)+12 = 8.5 and 7.93, respectively. For A1228+12 our new log(O/H)+12 = 7.73 is close to that recalculated from earlier data (7.68). Thus, the rederived metallicities allow us to remove these objects from the list of galaxies with Z < 1/20 Z_Sun.

  19. Development of precursors to produce metallic foams

    OpenAIRE

    Lopes, Bruno Pinto

    2011-01-01

    As espumas metálicas produzidas por metalurgia de pós têm vindo a ser cada vez mais utilizadas nas mais diversas aplicações. Actualmente estes materiais estão a ser utilizados em estruturas ultraleves, de absorção de energia e de amortecimento sonoro em veículos automóveis, comboios, eléctricos e aeronaves. O principal objectivo desta dissertação prendeu-se com o desenvolvimento de material precursor de qualidade para o fabrico de espumas de ligas de Alumínio. Para o efeito foram testados ...

  20. Biomimetic synthesis for precursor of muscone

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Muscone is a precious fragrant compound scarce in nature. Many attempts have been made to synthesize this unique natural product. In this work, the one- carbon unit transfer reaction of tetrahydrofolate coenzyme was initiated. Benzimidazolium salt was used as the tetrahydrofolate coenzyme model at formic acid oxidation level and di-Grignard reagent as the nucleophile to which one-carbon unit was transferred; the biomimetic synthesis of 2,15- hexade-canedione, a precursor of muscone, was successfully accomplished by using the addition-hydrolysis reaction of benzimidazolium salt with Grignard reagent. And an impor-tant useful method for the synthesis of muscone is provided.

  1. A preliminary assessment of individual doses in the environs of Berkeley, Gloucestershire, following the Chernobyl nuclear reactor accident

    International Nuclear Information System (INIS)

    A preliminary assessment has been made of the individual doses to critical group members of the public in the environs of Berkeley arising from fallout resulting from the Chernobyl accident. The assessment was based on measurements of airborne radionuclide concentrations, ground deposition and nuclide concentrations in rainwater, tapwater, grass, milk and green vegetables. The committed effective dose-equivalent was found to be as follows:- Adult - 200 μSv, 1 year old child - 500 μSv, the 10 year old child receiving a dose intermediate between these two values. The estimate accounts only for the nuclides measured and the specific exposure routes considered namely ingestion of milk and vegetables, inhalation and external exposure. However, it is believed that the inclusion of a range of other nuclides of potential significance, which may have been present but not measured, and potential intakes from additional routes is unlikely to increase the above estimates by more than a factor of 2. (author)

  2. Structure-based inference of molecular functions of proteins of unknown function from Berkeley Structural Genomics Center

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung-Hou; Shin, Dong Hae; Hou, Jingtong; Chandonia, John-Marc; Das, Debanu; Choi, In-Geol; Kim, Rosalind; Kim, Sung-Hou

    2007-09-02

    Advances in sequence genomics have resulted in an accumulation of a huge number of protein sequences derived from genome sequences. However, the functions of a large portion of them cannot be inferred based on the current methods of sequence homology detection to proteins of known functions. Three-dimensional structure can have an important impact in providing inference of molecular function (physical and chemical function) of a protein of unknown function. Structural genomics centers worldwide have been determining many 3-D structures of the proteins of unknown functions, and possible molecular functions of them have been inferred based on their structures. Combined with bioinformatics and enzymatic assay tools, the successful acceleration of the process of protein structure determination through high throughput pipelines enables the rapid functional annotation of a large fraction of hypothetical proteins. We present a brief summary of the process we used at the Berkeley Structural Genomics Center to infer molecular functions of proteins of unknown function.

  3. Environmental health-risk assessment for tritium releases from the National Tritium Labeling Facility (NTLF) at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.; Brand, K.P.

    1994-12-01

    This report is a health risk assessment that addresses continuous releases of tritium to the environment from the National Tritium Labeling Facility (NTLF) at the Lawrence Berkeley Laboratory (LBL). The NTLF contributes approximately 95% of all tritium releases from LBL. Transport and transformation models were used to determine the movement of tritium releases from the NRLF to the air, surface water, soils, and plants and to determine the subsequent doses to humans. These models were calibrated against environmental measurements of tritium levels in the vicinity of the NTLF and in the surrounding community. Risk levels were determined for human populations in each of these zones. Risk levels to both individuals and populations were calculated. In this report population risks and individual risks were calculated for three types of diseases--cancer, heritable genetic effects, and developmental and reproductive effects.

  4. Environmental health-risk assessment for tritium releases from the National Tritium Labeling Facility (NTLF) at Lawrence Berkeley Laboratory

    International Nuclear Information System (INIS)

    This report is a health risk assessment that addresses continuous releases of tritium to the environment from the National Tritium Labeling Facility (NTLF) at the Lawrence Berkeley Laboratory (LBL). The NTLF contributes approximately 95% of all tritium releases from LBL. Transport and transformation models were used to determine the movement of tritium releases from the NRLF to the air, surface water, soils, and plants and to determine the subsequent doses to humans. These models were calibrated against environmental measurements of tritium levels in the vicinity of the NTLF and in the surrounding community. Risk levels were determined for human populations in each of these zones. Risk levels to both individuals and populations were calculated. In this report population risks and individual risks were calculated for three types of diseases--cancer, heritable genetic effects, and developmental and reproductive effects

  5. Toward a Joint Inversion for Global Mantle Shear Velocity and Discontinuity Topography by Incorporating SS Precursor Waveforms into NACT

    Science.gov (United States)

    Zheng, Z.; Romanowicz, B. A.

    2010-12-01

    The Berkeley Global Seismology group has been developing global mantle shear velocity models (e.g. SAW24B16, Megnin and Romanowicz, 2000) by inverting a dataset of surface waveforms down to 60 sec and long-period body waveforms down to 32 sec. The frequency band of this dataset, however, is too low to retrieve fine scale structures of upper mantle discontinuities, which place vital constraints on the temperature, composition and dynamics of the mantle. In order for that, it is necessary to incorporate discontinuity-sensitive phases such as the SS precursors (e.g. Gu and Dziewonski, 2003). Previous work, however, generally only considers precursor travel times, while waveforms contain additional information on the character of the discontinuities. In our previous tomography studies, a normal mode coupling method known as the Non-linear Asymptotic Coupling Theory (NACT, Li and Romanowicz, 1995) has been successfully applied to compute 3D synthetic seismograms and sensitivity kernels. On one hand, by including across-branch mode coupling, it is able to bring out the ray character of body waves as well as the finite-frequency behavior of kernels. On the other hand, as an approximate approach, NACT is computationally much faster than purely numerical methods such as the Spectral Element Method (SEM, e.g. Komatitsch and Tromp, 2002). However, this method faces severe computational challenges when approaching higher frequencies at which the SS precursors are peaked (~10 sec). Under the classical mode coupling scheme, the time cost grows as (NS*NR)*fmax4, where NS is the number of sources, NR the number of receivers, and fmax the cutoff frequency. Here we develop an efficient formalism (after Capdeville, 2005) which reduces the cost dramatically to (NS+NR)*fmax2. Numerical tests show that synthetic seismograms computed from the new approach agree very well with those from the classical NACT. We then set up a framework for the joint inversion problem. With the new efficient

  6. Influência do mineral precursor no uso de uma bactéria para reparação de fissuras no betão

    OpenAIRE

    Vargas, Vânia Sofia Paulino

    2015-01-01

    Nesta dissertação foi feita uma avaliação da influência do mineral precursor no uso da bactéria Bacillus cohnii para reparação de fissuras no betão. Foram preparadas várias amassaduras de betão onde foram introduzidas bactérias da espécie Bacillus cohnii e combinadas com dois tipos diferentes de minerais precursores. Pretendeu-se avaliar qual o mineral precursor mais eficaz na formação de carbonato de cálcio quando combinado com esta bactéria. Através dos ensaios realizados fez-se um ac...

  7. Solar-cycle precursors and predictions

    CERN Document Server

    Jiang, Jie

    2013-01-01

    The sunspot number data during the past 400 years indicates that both the profile and the amplitude of the solar cycle have large variations. Some precursors of the solar cycle were identified aiming to predict the solar cycle. The polar field and the geomagnetic index are two precursors which are received the most attention. The geomagnetic variations during the solar minima are potentially caused by the solar polar field by the connection of the solar open flux. The robust prediction skill of the polar field indicates that the memory of the dynamo process is less than 11 yrs within the framework of the Babcock-Leighton flux transport dynamo. One possible reason to get the short magnetic memory is the high magnetic diffusivity in the convective zone. Our recent studies show that the radial downward pumping is another possible reason. Based upon the mechanism, we well simulate the cycle irregularities during RGO time period. This opens the possibility to set up a standard dynamo based model to predict the sol...

  8. Precursor solitons in a flowing complex plasma

    Science.gov (United States)

    Bandyopadhyay, Pintu; Jaiswal, Surabhi; Sen, Abhijit

    2015-11-01

    We report the first experimental observation of precursor solitons in a flowing dusty plasma. The nonlinear solitary dust acoustic waves (DAWs) are excited by a supersonic mass flow of the dust particles passing over an electrostatic potential hill. In a frame where the fluid is stationary and the hill is moving the solitons propagate in the upstream direction while wake structures consisting of linear DAWs are seen to propagate in the downstream direction. The experiments have been carried out in a U-shaped Dusty Plasma Experimental (DPEx) device where kaolin particles are immersed in a DC discharge argon plasma to form the dusty plasma and a floating wire mounted on the cathode creates a potential hill. The dust flow is induced by sudden changes in the hill height and the solitary structures are seen only for supersonic flows and up to an upper limit of the flow. A theoretical model description of the phenomenon will be provided and some practical implications of such precursor excitations for a charged object moving in a plasma will be discussed.

  9. Um modelo complexo do ato educativo

    OpenAIRE

    Sousa, Jesus Maria Angélica Fernandes

    2011-01-01

    O currículo, enquanto área de estudo e investigação, tem uma história relativamente recente, como todos sabemos. A sua afirmação identitária deveu-se ao facto de ter um objecto de estudo bem específico e delimitado, que não se confunde nem com a psicologia, nem com a sociologia, estas sim, ciências autónomas de longa data. No entanto, uma delimitação estrita das fronteiras do currículo, relativamente a outras áreas científicas que com ela interagem, pode levar a um seu esvaziamento concept...

  10. Die Kontroverse um das Freihandelsabkommen TTIP

    OpenAIRE

    Philipp M. Richter; Greta F. Schäffer

    2014-01-01

    Ein kurzer Name sorgt für eine anhaltende Debatte: TTIP [ti:t ]. Seit Beginn der Verhandlungen im Sommer 2013 trägt die mediale Berichterstattung über die geplante »Transatlantic Trade and Investment Partnership« zwischen der EU und den USA zur kritischen Auseinandersetzung mit der Thematik bei. Hierbei ergibt sich bisweilen die Schwierigkeit, sachlich fundierte Argumente von einseitigen Stellungnahmen zu differenzieren. Faktisch handelt es sich bei TTIP um ein Freihandels- und Investitionsab...

  11. Um Visitante do Rio de Janeiro Colonial

    Directory of Open Access Journals (Sweden)

    Jean M. Carvalho França

    1997-01-01

    Full Text Available O texto que se segue é a tradução de um manuscrito francês, intitulado Relâche du Vaisseau L'Arc-en-ciel à Rio de Janeiro, 1748, que se encontra na Biblioteca da Ajuda, em Lisboa. Trata-se de um relato anônimo, que dá conta da passagem do navio francês L'Arc-en-ciel pelo porto carioca. Tal relato, um curioso documento para a história dos nossos costumes, contém uma descrição da baía da Guanabara e da cidade do Rio de Janeiro, uma pequena análise do caráter da gente portuguesa do Brasil, um perfil do Governador Dom Fernando Freire e algumas considerações gerais sobre a situação do porto local e sobre os víveres disponíveis na região.The following text is a translation of a French manuscript named Relachê du Vaisseau L'Arc-en-ciel à Rio de Janeiro, 1748, which is in Biblioteca da Ajuda (Ajuda Library in Lisbon. It is an anonymous report and relates the stay of the French ship L'Arc-en-ciel in Rio de Janeiro harbour. Such report, a curious document for the history of our customs, has a description of Guanabara bay and Rio de Janeiro city, a brief analysis of the character of the Portuguese people in Brazil, a prolife of Governor Dom Fernando Freire and some considerations of the situation of local harbour and on the provisions available in that region.

  12. Luiz Gama: um abolicionista leitor de Renan

    Directory of Open Access Journals (Sweden)

    Ligia Fonseca Ferreira

    2007-08-01

    Full Text Available O hisoriador e filósofo Ernest Renan exerceu grande influência, hoje um tanto esquecida, sobre uma boa parte da elite intelectual brasileira engajada em reformas e movimentos que caracterizam a transição da Monarquia para a República. Dentre eles, destaca-se o abolicionista Luiz Gama, caso único de um ex-escravo autodidata que alcança projeção no cenário político e na República das Letras. Leitor precoce de Vida de Jesus, obra seminal do pensador francês, o advogado dos escravos é um dos primeiros a referir-se à obra que contou com inédita tradução brasileira, pouco depois de sua publicação na França. Por fim, observamos a apropriação das idéias renanianas por parte de personalidades diversas do ponto de vista social e racial, estabelecendo um paralelo entre Luiz Gama e Joaquim Nabuco.Historian and philosopher Ernest Renan exerts great influence - today somewhat forgotten - on a large part of the Brazilian intellectual elite that is engaged in reforms and movements which characterize the transition of a Monarchy to a Republic. Among these, abolitionist Luiz Gama stands out as the sole case of a former autodidact slave, who achieves a projection in the political scenario, and in the Republic of Letters. An early reader of Vida de Jesus, a seminal work of the French philosopher, the slaves’ attorney is one of the first to refer to the work, which counted with a first-hand, unprecedented Brazilian translation, shortly after its publication in France. Finally, we shall see the appropriation of Renanian ideas on the part of various personalities from the social and racial point of view, while establishing a parallel between Luiz Gama and Joaquim Nabuco.

  13. Paralisia periodica tireotoxica: registro de um caso

    Directory of Open Access Journals (Sweden)

    Athos Scherer Torres

    1979-06-01

    Full Text Available É relatado um caso de paralisia periódica tireotóxica. Os autores chamam a atenção para o fato de não haver registro de publicações semelhantes na literatura brasileira nos 10 últimos anos. São abordados diversos aspectos do diagnóstico diferencial com outros tipos de paralisia periódica.

  14. Precursor Mediated Synthesis of Nanostructured Silicas: From Precursor-Surfactant Ion Pairs to Structured Materials

    Directory of Open Access Journals (Sweden)

    Peter Hesemann

    2014-04-01

    Full Text Available The synthesis of nanostructured anionic-surfactant-templated mesoporous silica (AMS recently appeared as a new strategy for the formation of nanostructured silica based materials. This method is based on the use of anionic surfactants together with a co-structure-directing agent (CSDA, mostly a silylated ammonium precursor. The presence of this CSDA is necessary in order to create ionic interactions between template and silica forming phases and to ensure sufficient affinity between the two phases. This synthetic strategy was for the first time applied in view of the synthesis of surface functionalized silica bearing ammonium groups and was then extended on the formation of materials functionalized with anionic carboxylate and bifunctional amine-carboxylate groups. In the field of silica hybrid materials, the “anionic templating” strategy has recently been applied for the synthesis of silica hybrid materials from cationic precursors. Starting from di- or oligosilylated imidazolium and ammonium precursors, only template directed hydrolysis-polycondensation reactions involving complementary anionic surfactants allowed accessing structured ionosilica hybrid materials. The mechanistic particularity of this approach resides in the formation of precursor-surfactant ion pairs in the hydrolysis-polycondensation mixture. This review gives a systematic overview over the various types of materials accessed from this cooperative ionic templating approach and highlights the high potential of this original strategy for the formation of nanostructured silica based materials which appears as a complementary strategy to conventional soft templating approaches.

  15. A Tale of Three Campuses: Planning and Design in Response to the Cultural Heritages at Mills College, the University of California, Berkeley, and Stanford University

    Science.gov (United States)

    Fiene, Karen; Sabbatini, Robert

    2011-01-01

    How do forward-looking institutions with rich landscape and architectural heritages integrate contemporary programming and design? This article explores the evolution of the Mills College campus and compares it with two larger western universities: the University of California, Berkeley (UCB) and Leland Stanford, Jr., University (Stanford…

  16. Assessing Young Children's Views of Their Academic, Social, and Emotional Lives: An Evaluation of the Self-Perception Scales of the Berkeley Puppet Interview.

    Science.gov (United States)

    Measelle, Jeffrey R.; Ablow, Jennifer C.; Cowan, Philip A.; Cowan, Carolyn P.

    1998-01-01

    Examined psychometric properties of self-perception scales of the Berkeley Puppet Interview (BPI) with children at preschool, kindergarten, and first grade. Found that young children have a multidimensional self-concept that can be reliably measured. The BPI was sensitive to normative change and individual differences. Support for validity was…

  17. Construindo um Densímetro

    Directory of Open Access Journals (Sweden)

    Ricetti Rodrigo

    2002-01-01

    Full Text Available Para fins didáticos, é apresentada uma maneira de construir um densímetro, aparelho utilizadopara medir a densidade de fluidos. um aparato fácil de ser construído e muito simples de serutilizado. Sua principal vantagem sobre os densímetros que comercialmente encontramos, é a suacapacidade de medir a densidade de quaisquer líquidos, operando em qualquer faixa de densidade. Outra vantagem que apresenta, é a possibilidade de fazer uma medição relativa entre quaisquerlíquidos, não fazendo apenas a medição relativa à densidade da água. Desta maneira, pode-semedir, por exemplo, a densidade do mercúrio em relação ao éter, com este instrumento. Nota-seque, desta maneira, com apenas um instrumento determina-se a densidade de qualquer líquido, nãosendo necessário dispor-se de densímetros que operem em diversas faixas de densidade, como é ocaso dos instrumentos encontrados comercialmente.

  18. Functional Nanoporous Polymers from Block Copolymer Precursors

    DEFF Research Database (Denmark)

    Guo, Fengxiao

    Abstract Self-assembly of block copolymers provides well-defined morphologies with characteristic length scales in the nanometer range. Nanoporous polymers prepared by selective removal of one block from self-assembled block copolymers offer great technological promise due to their many potential...... applications as, e.g., membranes for separation and purification, templates for nanostructured materials, sensors, substrates for catalysis, low dielectric constant materials, photonic materials, and depots for controlled drug delivery. The development of nanoporous polymers with well controlled pore wall...... functionalities remains a great challenge due to the limitation of available polymer synthesis and the nanoscale confinement of the porous cavities. The main topic of this thesis is to develop methods for fabrication of functional nanoporous polymers from block copolymer precursors. A method has been developed...

  19. ON THE PRECURSORS OF FOSSIL GROUPS

    Directory of Open Access Journals (Sweden)

    Hrant Tovmassian

    2010-01-01

    Full Text Available Comparamos las magnitudes absolutas en la banda K de las galaxias más brillantes en cúmulos de Bautz-Morgan tipo I con las de las galaxias brillantes de grupos fósiles. Demostramos que las galaxias más brillantes en grupos fósiles son, en promedio, más débiles que sus contrapartes en los cúmulos. Además, mostramos que la luminosidad de la galaxia más brillante depende de la riqueza del cúmulo. Concluimos que los precursores de grupos fóiles fueron en promedio cúmulos po- bres.

  20. ON THE PRECURSORS OF FOSSIL GROUPS

    OpenAIRE

    Hrant Tovmassian

    2010-01-01

    Comparamos las magnitudes absolutas en la banda K de las galaxias más brillantes en cúmulos de Bautz-Morgan tipo I con las de las galaxias brillantes de grupos fósiles. Demostramos que las galaxias más brillantes en grupos fósiles son, en promedio, más débiles que sus contrapartes en los cúmulos. Además, mostramos que la luminosidad de la galaxia más brillante depende de la riqueza del cúmulo. Concluimos que los precursores de grupos fóiles fueron en promedio cúmulos po- bres.

  1. Enhanced depth imaging optical coherence tomography of precursor cell leukemic choroidopathy before and after chemotherapy

    Directory of Open Access Journals (Sweden)

    Murtaza K Adam

    2015-01-01

    Full Text Available Serous retinal detachment (SRD can be the initial manifestation of leukemia. Herein, we explore the retinal and choroidal features on enhanced depth imaging optical coherence tomography (EDI-OCT of SRD in a patient with undiagnosed leukemia. A 23-year-old male developed blurred visual acuity of 20/200 in the right eye oculus dexter (OD and 20/200 in the left eye oculus sinister (OS. Funduscopically, he manifested serous macular detachment in both eyes oculi uterque (OU without hemorrhagic retinal abnormalities. EDI-OCT disclosed macular detachment OU and homogeneous, marked choroidal opacification with thickening to 724 ΅m OD and estimated >600 ΅m OS and with loss of choroidal detail OU. Peripheral blood smears revealed severe thrombocytopenia and normal leukocyte count. Peripheral cytochemisty, immunophenotyping, and bone marrow aspirate confirmed the presence of atypical lymphoblasts, fulfilling criteria for precursor cell leukemia. Following systemic chemotherapy, the visual acuity improved to 20/25 OD and 20/20 OS. On EDI-OCT, the choroidal thickening resolved to 431 um OD and 443 um OS, leaving a normal choroidal appearance. Massive choroidal infiltration with leukemic cells could be the cause of serous macular detachment found in patients with newly diagnosed leukemia.

  2. Preparation and Characterization of TaN ALD Precursors

    Institute of Scientific and Technical Information of China (English)

    Delong Zhang; Tracy Yund; Cynthia A.Hoover

    2004-01-01

    High purity organic-tantalum precursors for thin film ALD TaN were synthesized and characterized.Vapor pressure and thermal stability of these precursors were studied.From the vapor pressure analysis,it was found that TBTEMT has a higher vapor pressure than any other published liquid TaN precursor,including TBTDET,TAITMATA,and IPTDET.Thermal stability of the alkyl groups on the precursors was investigated using a 1H NMR technique.The results indicated that the tertbutylimino group is the most stable group on TBTDET and TBTEMT as compared to the dialkylamido groups.Thermal stability of TaN precursors decreased in the following order:TBTDET > PDMAT > TBTEMT.In conclusion,precursor vapor pressure and thermal stability were tuned by making slight variations in the ligand sphere around the metal center.

  3. The crustal micro-deformation anomaly and the credible precursor*

    Institute of Scientific and Technical Information of China (English)

    张雁滨; 蒋骏; 钱家栋; 陈京; 和升棋; 张燕; 和平

    2002-01-01

    @@ What is a credible seismic precursor in observation of deformation A real seismic precursor ought to be resulted from the variations in the earth strain and stress. The deformation observation can provide the information during earthquake gestation and occurrence period for us. Usually the seismic precursors can be divided into field and epicentral region precursors. The precursor information is very useful for seismic prediction from epicentral region or near epicentral region. Micro-deformation observation mainly includes tilt, strain and gravity observation. Compared with GPS, geodesy and mobile deformation observation, micro-deformation (tilt, strain) shows the change of deformation which is continual in a limited volume with dominant observed range of 10(6~10(10 m. Because the variation of the crustal nature and cracking can be directly obtained by micro-deformation observation, it is an effective way to find middle-short term and short-term precursor.

  4. STIMULATED PLATELETS RELEASE AMYLOID β–PROTEIN PRECURSOR

    OpenAIRE

    Cole, Gregory M.; Galasko, Douglas; Shapiro, I. Paul; Saitoh, Tsunao

    1990-01-01

    Human platelets can be stimulated by thrombin or ionomycin to secrete soluble truncated amyloid β–protein precursor and particulate membrane fragments which contain C-terminal and N-terminal immunoreactive amyloid β–protein precursor. This suggests a possible circulating source of β–protein in serum which may play a role in the formation of amyloid deposits. The release of soluble amyloid β-protein precursor could be involved in normal platelet physiology.

  5. AN EVALUATION OF STRENGTHENING PRECURSORS TO INCREASE PRESCHOOLER COMPLIANCE

    OpenAIRE

    Kraus, Aaron J; Hanley, Gregory P; Cesana, Lori L; Eisenberg, Danielle; Jarvie, Adam C

    2012-01-01

    We evaluated the strategy of increasing precursors to compliance on the compliance of 2 preschool boys. Modeling and differential reinforcement were used to increase specific responses to his name being called prior to the opportunity to comply with an instruction. The precursors were stopping the ongoing activity and orienting to, making eye contact with, and saying “yes” to the instructor. High levels of precursors occurred during treatment, and increases in compliance also were observed, e...

  6. DSC Study on the Polyacrylonitrile Precursors for Carbon Fibers

    Institute of Scientific and Technical Information of China (English)

    Wangxi ZHANG; Musen LI

    2005-01-01

    Different polyacrylonitrile (PAN) precursor fibers that displayed various thermal properties were studied by using differential scanning calorimetry (DSC). Results showed that some commercial PAN precursor fibers displayed double separated peaks and these fibers were of high quality because of their process stability during their conversion to carbon fibers of high performance. Some fabrication processes, such as spinning, drawing, could not apparently change the DSC features of a PAN precursor fiber. It was concluded that the thermal properties of a PAN precursor fiber was mainly determined from its comonomer content type and compositions.

  7. Desenvolvimento de um vidrado opaco brilhante

    OpenAIRE

    Ladeira, Isabel Cristina Gomes dos Santos

    2008-01-01

    Com o presente trabalho, pretendeu-se avaliar a viabilidade técnica e económica da produção dum vidrado cerâmico opaco brilhante, que permitisse substituir o actualmente utilizado na produção de revestimento por bicozedura rápida. A formulação do vidrado teve em vista não só uma melhoria significativa de qualidade mas também, a obtenção de um produto cerâmico para revestimento, economicamente vantajoso. O estudo foi realizado em particular para o caso de revestimentos confor...

  8. Berkeley Supernova Ia Program I: Observations, Data Reduction, and Spectroscopic Sample of 582 Low-Redshift Type Ia Supernovae

    CERN Document Server

    Silverman, Jeffrey M; Filippenko, Alexei V; Ganeshalingam, Mohan; Barth, Aaron J; Chornock, Ryan; Griffith, Christopher V; Kong, Jason J; Lee, Nicholas; Leonard, Douglas C; Matheson, Thomas; Miller, Emily G; Steele, Thea N; Barris, Brian J; Bloom, Joshua S; Cobb, Bethany E; Coil, Alison L; Desroches, Louis-Benoit; Gates, Elinor L; Ho, Luis C; Jha, Saurabh W; Kandrashoff, Michael T; Li, Weidong; Mandel, Kaisey S; Modjaz, Maryam; Moore, Matthew R; Mostardi, Robin E; Papenkova, Marina S; Park, Sung; Perley, Daniel A; Poznanski, Dovi; Reuter, Cassie A; Scala, James; Serduke, Franklin J D; Shields, Joseph C; Swift, Brandon J; Tonry, John L; Van Dyk, Schuyler D; Wang, Xiaofeng; Wong, Diane S

    2012-01-01

    In this first paper in a series we present 1298 low-redshift (z < 0.2) optical spectra of 582 Type Ia supernovae (SNe Ia) observed from 1989 through 2008 as part of the Berkeley SN Ia Program (BSNIP). 584 spectra of 199 SNe Ia have well-calibrated light curves with measured distance moduli, and many of the spectra have been corrected for host-galaxy contamination. Most of the data were obtained using the Kast double spectrograph mounted on the Shane 3 m telescope at Lick Observatory and have a typical wavelength range of 3300-10,400 Ang., roughly twice as wide as spectra from most previously published datasets. We present our observing and reduction procedures, and we describe the resulting SN Database (SNDB), which will be an online, public, searchable database containing all of our fully reduced spectra and companion photometry. In addition, we discuss our spectral classification scheme (using the SuperNova IDentification code, SNID; Blondin & Tonry 2007), utilizing our newly constructed set of SNID ...

  9. The electromagnetic Brillouin precursor in one-dimensional photonic crystals

    NARCIS (Netherlands)

    Uitham, R.; Hoenders, B. J.

    2008-01-01

    We have calculated the electromagnetic Brillouin precursor that arises in a one-dimensional photonic crystal that consists of two homogeneous slabs which each have a single electron resonance. This forerunner is compared with the Brillouin precursor that arises in a homogeneous double-electron reson

  10. Geometrizing configurations. Heinrich Hertz and his mathematical precursors

    DEFF Research Database (Denmark)

    Lützen, Jesper

    1999-01-01

    A comparison between the methods used by Heinrich hertz and his mathematician precursors such as Liouville, Lipschitz and Darboux in order to apply differential geometry in mechanics......A comparison between the methods used by Heinrich hertz and his mathematician precursors such as Liouville, Lipschitz and Darboux in order to apply differential geometry in mechanics...

  11. Effects of rhythmic precursors on perception of stress/syllabicity

    Science.gov (United States)

    Stilp, Christian E.; Kluender, Keith R.

    2005-09-01

    Rhythmic structure is a common property of many environmental sounds including speech. Here, perceptual effects of preceding rhythmic context are assessed in experiments employing edited words for which perceived stress/syllabicity are assessed. A series of edited naturally spoken words varying perceptually from ``polite'' to ``plight,'' was created by deleting initial-vowel glottal pulses from a recording of ``polite.'' Words were identified following nonspeech precursor sequences having either trochaic (strong-weak) or iambic (weak-strong) rhythmic patterns. Precursors consisted of a harmonic spectrum (-6-dB/octave slope) filtered by four sinusoidally modulated single-pole filters. Trochaic (strong-weak) and iambic (weak-strong) rhythmic patterns were created by varying amplitude, pitch, and duration in successive segments (akin to beats) of the precursors. Precursors were comprised of two to six repetitions of these patterns. Following trochaic precursors, listeners were more likely to report hearing ``polite'' (iambic). This pattern of results indicates that perception did not assimilate to precursor pattern, consistent with rhythmic expectancy. Instead, perception shifted in a way that contrasts with precursor temporal pattern. Additional results with precursors that are more and less like speech are being conducted to further understand how auditory perception adjusts for temporal and spectral regularities. [Work supported by NIDCD.

  12. Topographical and Functional Properties of Precursors to Severe Problem Behavior

    Science.gov (United States)

    Fahmie, Tara A.; Iwata, Brian A.

    2011-01-01

    A literature search identified 17 articles reporting data on 34 subjects who engaged in precursors to severe problem behavior, which we examined to identify topographical and functional characteristics. Unintelligible vocalization was the most common precursor to aggression (27%) and property destruction (29%), whereas self- or nondirected…

  13. Precursors to Aggression Are Evident by 6 Months of Age

    Science.gov (United States)

    Hay, Dale F.; Waters, Cerith S.; Perra, Oliver; Swift, Naomi; Kairis, Victoria; Phillips, Rebecca; Jones, Roland; Goodyer, Ian; Harold, Gordon; Thapar, Anita; van Goozen, Stephanie

    2014-01-01

    We tested the hypothesis that developmental precursors to aggression are apparent in infancy. Up to three informants rated 301 firstborn infants for early signs of anger, hitting and biting; 279 (93%) were assessed again as toddlers. Informants' ratings were validated by direct observation at both ages. The precursor behaviours were…

  14. An Evaluation of Strengthening Precursors to Increase Preschooler Compliance

    Science.gov (United States)

    Kraus, Aaron J.; Hanley, Gregory P.; Cesana, Lori L.; Eisenberg, Danielle; Jarvie, Adam C.

    2012-01-01

    We evaluated the strategy of increasing precursors to compliance on the compliance of 2 preschool boys. Modeling and differential reinforcement were used to increase specific responses to his name being called prior to the opportunity to comply with an instruction. The precursors were stopping the ongoing activity and orienting to, making eye…

  15. Pair fireball precursors of neutron star mergers

    Science.gov (United States)

    Metzger, Brian D.; Zivancev, Charles

    2016-10-01

    If at least one neutron star (NS) is magnetized in a binary NS merger, then the orbital motion of the conducting companion during the final inspiral induces a strong voltage and current along the magnetic field lines connecting the NSs. If a modest fraction η of the extracted electromagnetic power extracted accelerates relativistic particles, the resulting gamma-ray emission a compact volume will result in the formation of an electron-positron pair fireball. Applying a steady-state pair wind model, we quantify the detectability of the precursor fireball with gamma-ray satellites. For η ˜ 1 the gamma-ray detection horizon of Dmax ≈ 10(Bd/1014 G)3/4 Mpc is much closer than the Advanced Laser Interferometer Gravitational-Wave Observatory (LIGO)/Virgo horizon of 200 Mpc, unless the NS surface magnetic field strength is very large, B_d ≲ 10^{15} G. Given the quasi-isotropic nature of the emission, mergers with weaker NS fields could contribute a nearby population of short gamma-ray bursts. Power not dissipated close to the binary is carried to infinity along the open field lines by a large-scale Poynting flux. Reconnection within this outflow, well outside of the pair photosphere, provides a potential site for non-thermal emission, such as a coherent millisecond radio burst.

  16. Identification, Selection, and Enrichment of Cardiomyocyte Precursors

    Directory of Open Access Journals (Sweden)

    Bianca Ferrarini Zanetti

    2013-01-01

    Full Text Available The large-scale production of cardiomyocytes is a key step in the development of cell therapy and tissue engineering to treat cardiovascular diseases, particularly those caused by ischemia. The main objective of this study was to establish a procedure for the efficient production of cardiomyocytes by reprogramming mesenchymal stem cells from adipose tissue. First, lentiviral vectors expressing neoR and GFP under the control of promoters expressed specifically during cardiomyogenesis were constructed to monitor cell reprogramming into precardiomyocytes and to select cells for amplification and characterization. Cellular reprogramming was performed using 5′-azacytidine followed by electroporation with plasmid pOKS2a, which expressed Oct4, Sox2, and Klf4. Under these conditions, GFP expression began only after transfection with pOKS2a, and less than 0.015% of cells were GFP+. These GFP+ cells were selected for G418 resistance to find molecular markers of cardiomyocytes by RT-PCR and immunocytochemistry. Both genetic and protein markers of cardiomyocytes were present in the selected cells, with some variations among them. Cell doubling time did not change after selection. Together, these results indicate that enrichment with vectors expressing GFP and neoR under cardiomyocyte-specific promoters can produce large numbers of cardiomyocyte precursors (CMPs, which can then be differentiated terminally for cell therapy and tissue engineering.

  17. Formation of biomolecule precursors in space

    Energy Technology Data Exchange (ETDEWEB)

    Geppert, W D [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Vigren, E [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Hamberg, M [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Zhaunerchyk, V [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Thomas, R D [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Kaminska, M [Institute of Physics, Swieetokrzyska Academy, ul. Swieokrzyska 15, PL-25406, Kielce (Poland); Millar, T J [Astrophysics Research Centre, Queen' s University Belfast, BT7 1NN, Belfast, Northern Ireland (United Kingdom); Semaniak, J [Institute of Physics, Swieetokrzyska Academy, ul. Swieokrzyska 15, PL-25406, Kielce (Poland); Roberts, H [Astrophysics Research Centre, Queen' s University Belfast, BT7 1NN, Belfast, Northern Ireland (United Kingdom); Hellberg, F [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Oesterdahl, F [Department of Physics, Royal Institute of Technology, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Ehlerding, A [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden); Larsson, M [Department of Physics, Stockholm University, Alba Nova, Roslagstullbacken 21, SE-10691, Stockholm (Sweden)

    2007-11-15

    Alcohols and nitriles not only play an important role as templates for synthesis of larger molecules in the interstellar medium and planetary atmospheres, but they can also be regarded as precursors for biomolecules. Alcohols can form carbohydrates through reaction with HCO and nitriles can be hydrolysed to amino acids in aqueous solutions, which is the final step of the well-known Strecker synthesis. Therefore the question of the pathways of formation of alcohols and nitriles and the efficiency and the product distribution of their subsequent degradation reactions in the above-mentioned astrophysical environments is of great interest. In both processes dissociative recombination reactions of protonated nitriles and alcohols may play a major role and are included in models of interstellar clouds and planetary atmospheres. However, the reaction rate coefficients and product branching ratios for the majority of these processes are so far still unknown, which adversely affects the quality of predictions of model calculations. In this Contribution, we therefore present branching ratios and rate constants of the dissociative recombination of protonated methanol (CH{sub 3}OH{sub 2}), as well as protonated acetonitrile (CH{sub 3}CNH{sup +}), acrylonitrile (C{sub 2}H{sub 3}CNH{sup +}) and cyanoacetylene (HC{sup 3}NH{sup +}). The impact of the obtained new data on model calculations of abundances of important interstellar molecules in dark clouds is discussed.

  18. Pair Fireball Precursors of Neutron Star Mergers

    CERN Document Server

    Metzger, Brian D

    2016-01-01

    If at least one neutron star (NS) is magnetized in a binary NS merger, then the orbital motion of the conducting companion through its dipole field during the final inspiral induces a strong voltage and current along the magnetic field lines connecting the two objects. If a modest fraction eta of the electromagnetic power extracted during the inspiral is used to accelerate relativistic particles, the resulting gamma-ray emission in such a compact volume will result in the formation of a thermal electron-positron pair fireball. Applying the steady-state pair wind model of Paczynski (1986), we quantify the luminosities and temperatures of the precursor fireball and its detectability with gamma-ray satellites. Under the assumption that eta ~ 1, the gamma-ray detection horizon of Dmax ~ 20(Bd/1e14 G) is much closer than the Advanced LIGO/Virgo horizon of 200 Mpc, unless the surface magnetic field of the NS is very strong, Bd > 1e15 G. Given the quasi-isotropic nature of the emission, a sub-population of mergers w...

  19. Proinsulin: from hormonal precursor to neuroprotective factor

    Directory of Open Access Journals (Sweden)

    Flora eDe Pablo

    2011-09-01

    Full Text Available In the last decade, non-canonical functions have been described for several molecules with hormone-like activities in different stages of vertebrate development. Since its purification in the 1960s, proinsulin has been one of the best described hormonal precursors, though it has been overwhelmingly studied in the context of insulin, the mature protein secreted by the pancreas. Beginning with our discovery of the presence and precise regulation of proinsulin mRNA in early neurulation and neurogenesis, we uncovered a role for proinsulin in cell survival in the developing nervous system. We subsequently demonstrated the ability of proinsulin to prevent pathological cell death and delay photoreceptor degeneration in a mouse model of retinitis pigmentosa. In this review, we focus on the evolution of proinsulin/insulin, beginning with insulin-like peptides expressed in mainly the neurosecretory cells of some invertebrates. We summarize findings related to the regulation of proinsulin expression during development and discuss the possible effects of proinsulin in neural cells or tissue, and its potential as a neuroprotective molecule.

  20. Precursors to Interstellar Shocks of Solar Origin

    Science.gov (United States)

    Gurnett, D. A.; Kurth, W. S.; Stone, E. C.; Cummings, A. C.; Krimigis, S. M.; Decker, R. B.; Ness, N. F.; Burlaga, L. F.

    2015-12-01

    On or about 2012 August 25, the Voyager 1 spacecraft crossed the heliopause into the nearby interstellar plasma. In the nearly three years that the spacecraft has been in interstellar space, three notable particle and field disturbances have been observed, each apparently associated with a shock wave propagating outward from the Sun. Here, we present a detailed analysis of the third and most impressive of these disturbances, with brief comparisons to the two previous events, both of which have been previously reported. The shock responsible for the third event was first detected on 2014 February 17 by the onset of narrowband radio emissions from the approaching shock, followed on 2014 May 13 by the abrupt appearance of intense electron plasma oscillations generated by electrons streaming outward ahead of the shock. Finally, the shock arrived on 2014 August 25, as indicated by a jump in the magnetic field strength and the plasma density. Various disturbances in the intensity and anisotropy of galactic cosmic rays were also observed ahead of the shock, some of which are believed to be caused by the reflection and acceleration of cosmic rays by the magnetic field jump at the shock, and/or by interactions with upstream plasma waves. Comparisons to the two previous weaker events show somewhat similar precursor effects, although differing in certain details. Many of these effects are very similar to those observed in the region called the "foreshock" that occurs upstream of planetary bow shocks, only on a vastly larger spatial scale.

  1. Bone formation on synthetic precursors of hydroxyapatite.

    Science.gov (United States)

    Suzuki, O; Nakamura, M; Miyasaka, Y; Kagayama, M; Sakurai, M

    1991-05-01

    The aim of this study was to investigate the reaction of skeletal tissue to various synthetic calcium phosphate (Ca-P) compounds in vivo. Five synthetic Ca-P compounds were implanted into the subperiosteal area of the calvaria of 7-week-old BALB/c mice for one to 15 weeks. Synthetic compounds were dicalcium phosphate (DCP), octacalcium phosphate (OCP), amorphous calcium phosphate (ACP), Ca-deficient hydroxyapatite and hydroxyapatile (HA). Implanted DCP, OCP and ACP were found to be converted to apatitic phase by x-ray microdiffraction analysis using undecalcified specimens. Structure of bone was found out on all of Ca-P compounds eventually at late stage under the light microscope, but the rate of bone formation calculated from a number of experiments varied on respective synthetic Ca-P compound. It was high as 80% for DCP, OCP and ACP, but was low as 5.6% for Ca-deficient HA, and no reaction was found for HA at the stage of 3 weeks. Fine filaments and granular materials in the newly formed bone matrix were detected at 7 days around the remnants of OCP particles which already converted to apatitic phase by ultrastructural study of decalcified specimens. These structures were very similar to the components of bone nodules seen in intramembranous osteogenesis. It is postulated that the precursors of HA have an important role in intramembranous osteogenesis.

  2. Enzymatic synthesis of vitamin B6 precursor

    Directory of Open Access Journals (Sweden)

    Prlainović Nevena Ž.

    2013-01-01

    Full Text Available 3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa (triacylglycerol ester hydrolases, EC 3.1.1.3. This work shows new experimental data and mathematical modeling of lipase catalyzed synthesis of 3-cyano-4-ethoxymethyl-6-methyl-2-pyridone, starting from 1-ethoxy-2,4-pentanedione and 2-cyanoacetamide. Kinetic measurements were done at 50 oC with enzyme concentration of 1.2 % w/v. Experimental results were fitted with two kinetic models: the ordered bi-ter and ping-pong bi-ter model, and the initial rates of the reaction were found to correlate best with a ping-pong bi-ter mechanism with inhibition by 2-cyanoacetamide. Obtained specificity constants indicated that lipase from C. rugosa had higher affinity towards 1-ethoxy-2,4-pentanedione and less bulky substrates. [Projekat Ministarstva nauke Republike Srbije, br. 172013, br. III 46010 and br. 172049

  3. Bacterial Cellular Materials as Precursors of Chloroform

    Science.gov (United States)

    Wang, J.; Ng, T.; Zhang, Q.; Chow, A. T.; Wong, P.

    2011-12-01

    The environmental sources of chloroform and other halocarbons have been intensively investigated because their effects of stratospheric ozone destruction and environmental toxicity. It has been demonstrated that microorganisms could facilitate the biotic generation of chloroform from natural organic matters in soil, but whether the cellular materials itself also serves as an important precursor due to photo-disinfection is poorly known. Herein, seven common pure bacterial cultures (Acinetobacter junii, Aeromonas hydrophila, Bacillus cereus, Bacillus substilis, Escherichia coli, Shigella sonnei, Staphylococcus sciuri) were chlorinated to evaluate the yields of chloroform, dibromochloromethane, dichlorobromomethane, and bromoform. The effects of bromide on these chemical productions and speciations were also investigated. Results showed that, on average, 5.64-36.42 μg-chloroform /mg-C were generated during the bacterial chlorination, in similar order of magnitude to that generated by humic acid (previously reported as 78 μg-chloroform/mg-C). However, unlike humic acid in water chlorination, chloroform concentration did not simply increase with the total organic carbon in water mixture. In the presence of bromide, the yield of brominated species responded linearly to the bromide concentration. This study provides useful information to understand the contributions of chloroform from photodisinfection processes in coastal environments.

  4. The Amyloid Precursor Protein Controls PIKfyve Function.

    Science.gov (United States)

    Balklava, Zita; Niehage, Christian; Currinn, Heather; Mellor, Laura; Guscott, Benjamin; Poulin, Gino; Hoflack, Bernard; Wassmer, Thomas

    2015-01-01

    While the Amyloid Precursor Protein (APP) plays a central role in Alzheimer's disease, its cellular function still remains largely unclear. It was our goal to establish APP function which will provide insights into APP's implication in Alzheimer's disease. Using our recently developed proteo-liposome assay we established the interactome of APP's intracellular domain (known as AICD), thereby identifying novel APP interactors that provide mechanistic insights into APP function. By combining biochemical, cell biological and genetic approaches we validated the functional significance of one of these novel interactors. Here we show that APP binds the PIKfyve complex, an essential kinase for the synthesis of the endosomal phosphoinositide phosphatidylinositol-3,5-bisphosphate. This signalling lipid plays a crucial role in endosomal homeostasis and receptor sorting. Loss of PIKfyve function by mutation causes profound neurodegeneration in mammals. Using C. elegans genetics we demonstrate that APP functionally cooperates with PIKfyve in vivo. This regulation is required for maintaining endosomal and neuronal function. Our findings establish an unexpected role for APP in the regulation of endosomal phosphoinositide metabolism with dramatic consequences for endosomal biology and important implications for our understanding of Alzheimer's disease. PMID:26125944

  5. The Amyloid Precursor Protein Controls PIKfyve Function.

    Directory of Open Access Journals (Sweden)

    Zita Balklava

    Full Text Available While the Amyloid Precursor Protein (APP plays a central role in Alzheimer's disease, its cellular function still remains largely unclear. It was our goal to establish APP function which will provide insights into APP's implication in Alzheimer's disease. Using our recently developed proteo-liposome assay we established the interactome of APP's intracellular domain (known as AICD, thereby identifying novel APP interactors that provide mechanistic insights into APP function. By combining biochemical, cell biological and genetic approaches we validated the functional significance of one of these novel interactors. Here we show that APP binds the PIKfyve complex, an essential kinase for the synthesis of the endosomal phosphoinositide phosphatidylinositol-3,5-bisphosphate. This signalling lipid plays a crucial role in endosomal homeostasis and receptor sorting. Loss of PIKfyve function by mutation causes profound neurodegeneration in mammals. Using C. elegans genetics we demonstrate that APP functionally cooperates with PIKfyve in vivo. This regulation is required for maintaining endosomal and neuronal function. Our findings establish an unexpected role for APP in the regulation of endosomal phosphoinositide metabolism with dramatic consequences for endosomal biology and important implications for our understanding of Alzheimer's disease.

  6. O vampiro, um não morto ainda vivo

    OpenAIRE

    Max Kohn

    2012-01-01

    O que um vampiro representa? Por que ocupa tal lugar na cultura? O vampiro é um invariante cultural com diferenças culturais. O vivente é um não morto (undead), e o não morto ainda está vivo. Do ponto de vista psicanalítico, qual é, então, essa relação com os dentes e com a mordida que contamina, que faz com que o outro se torne também um vampiro? O vampiro é um bebê que morde e tem um desejo ambivalente de imortalidade. O leite materno é vital como o é o sangue para o vampiro. A brincadeira ...

  7. DISCURSO E VERDADE: SEIS CONFERÊNCIAS DADAS POR MICHEL FOUCAULT, EM BERKELEY, ENTRE OUTUBRO E NOVEMBRO DE 1983, SOBRE A PARRHESIA - APRESENTAÇÃO

    Directory of Open Access Journals (Sweden)

    Os Editores da Prometeus

    2013-10-01

    Full Text Available O presente trabalho é a tradução, produzida pela equipe de tradutores daPrometeus, de O Discurso e a Verdade: a problematização da parrhesia, seisconferências de Michel Foucault proferidas em inglês na Universidade daCalifórnia, em Berkeley, entre outubro e novembro de 1983. A transcrição que nosserviu de base para a tradução foi editada em inglês em 1985 por Joseph Pearson ecompilada a partir das gravações das conferências, disponíveis para download no sítiodo Media Resources Center da Moffitt Library (UC Berkeley1. Essa transcrição foireeditada em 1999 por www.repb.net.

  8. Design, fabrication, and calibration of curved integral coils for measuring transfer function, uniformity, and effective length of LBL ALS [Lawrence Berkeley Laboratory Advanced Light Source] Booster Dipole Magnets

    International Nuclear Information System (INIS)

    A matched pair of curved integral coils has been designed, fabricated and calibrated at Lawrence Berkeley Laboratory for measuring Advanced Light Source (ALS) Booster Dipole Magnets. Distinctive fabrication and calibration techniques are described. The use of multifilar magnet wire in fabrication integral search coils is described. Procedures used and results of AC and DC measurements of transfer function, effective length and uniformity of the prototype booster dipole magnet are presented in companion papers. 8 refs

  9. AN INTRODUCTION TO EXPLORING LAW, DISABILITY, AND THE CHALLENGE OF EQUALITY IN CANADA AND THE UNITED STATES: PAPERS FROM THE BERKELEY SYMPOSIUM

    Directory of Open Access Journals (Sweden)

    Laverne Jacobs

    2015-10-01

    Full Text Available It brings me great pleasure to write this Introduction to Exploring Law, Disability, and the Challenge of Equality in Canada and the United States. This special collection of articles in the Windsor Yearbook of Access to Justice [WYAJ] stems from a symposium of the same name held at the Berkeley Law School at the University of California on 5 December 2014. Writing this introduction allows me to bring together my identities as a law and disability scholar, the principal organizer and convener of the Berkeley Symposium, and editor-in-chief of the WYAJ. In these roles, I have had the opportunity to engage with this set of articles and their authors in a distinct way – from the early versions of these articles through to the final peer-reviewed publications. The Berkeley Symposium is the first conference, of which we are aware, to bring together scholars and experts from both Canada and the United States to present research and exchange ideas on equality issues affecting persons with disabilities in both countries.1 Each academic was invited to write about an equality issue of their choice that is of contemporary concern to persons with disabilities, and to focus on Canada, the United States,or both, at their  option. The result is a set of articles that is simultaneously introspective and comparative.

  10. A critical review of Electric Earthquake Precursors

    Directory of Open Access Journals (Sweden)

    F. Vallianatos

    2001-06-01

    Full Text Available The generation of transient electric potential prior to rupture has been demonstrated in a number of laboratory experiments involving both dry and wet rock specimens. Several different electrification effects are responsible for these observations, but how these may scale up co-operatively in large heterogeneous rock volumes, to produce observable macroscopic signals, is still incompletely understood. Accordingly, the nature and properties of possible Electric Earthquake Precursors (EEP are still inadequately understood. For a long time observations have been fragmentary, narrow band and oligo-parametric (for instance, the magnetic field was not routinely measured. In general, the discrimination of purported EEP signals relied on "experience" and ad hoc empirical rules that could be shown unable to guarantee the validity of the data. In consequence, experimental studies have produced a prolific variety of signal shape, complexity and duration but no explanation for the apparently indefinite diversity. A set of inconsistent or conflicting ideas attempted to explain such observations, including different concepts about the EEP source region (near the observer or at the earthquake focus and propagation (frequently assumed to be guided by peculiar geoelectric structure. Statistics was also applied to establish the "beyond chance" association between presumed EEP signals and earthquakes. In the absence of well constrained data, this approach ended up with intense debate and controversy but no useful results. The response of the geophysical community was scepticism and by the mid-90's, the very existence of EEP was debated. At that time, a major re-thinking of EEP research began to take place, with reformulation of its queries and objectives and refocusing on the exploration of fundamental concepts, less on field experiments. The first encouraging results began to appear in the last two years of the 20th century. Observation technologies are mature

  11. PRECOMBUSTION REMOVAL OF HAZARDOUS AIR POLLUTANT PRECURSORS

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2000-10-09

    In response to growing environmental concerns reflected in the 1990 Clean Air Act Amendment (CAAA), the United States Department of Energy (DOE) sponsored several research and development projects in late 1995 as part of an initiative entitled Advanced Environmental Control Technologies for Coal-Based Power Systems. The program provided cost-shared support for research and development projects that could accelerate the commercialization of affordable, high-efficiency, low-emission, coal-fueled electric generating technologies. Clean coal technologies developed under this program would serve as prototypes for later generations of technologies to be implemented in the industrial sector. In order to identify technologies with the greatest potential for commercial implementation, projects funded under Phase I of this program were subject to competitive review by DOE before being considered for continuation funding under Phase II. One of the primary topical areas identified under the DOE initiative relates to the development of improved technologies for reducing the emissions of air toxics. Previous studies have suggested that many of the potentially hazardous air pollutant precursors (HAPPs) occur as trace elements in the mineral matter of run-of-mine coals. As a result, these elements have the potential to be removed prior to combustion at the mine site by physical coal cleaning processes (i.e., coal preparation). Unfortunately, existing coal preparation plants are generally limited in their ability to remove HAPPs due to incomplete liberation of the mineral matter and high organic associations of some trace elements. In addition, existing physical coal cleaning plants are not specifically designed or optimized to ensure that high trace element rejections may be achieved.

  12. The reliability of radon as seismic precursor

    Science.gov (United States)

    Emilian Toader, Victorin; Moldovan, Iren Adelina; Ionescu, Constantin; Marmureanu, Alexandru

    2016-04-01

    Our multidisciplinary network (AeroSolSys) located in Vrancea (Curvature Carpathian Mountains) includes radon concentration monitoring in five stations. We focus on lithosphere and near surface low atmosphere phenomena using real-time information about seismicity, + / - ions, clouds, solar radiation, temperature (air, ground), humidity, atmospheric pressure, wind speed and direction, telluric currents, variations of the local magnetic field, infrasound, variations of the atmospheric electrostatic field, variations in the earth crust with inclinometers, electromagnetic activity, CO2 concentration, ULF radio wave propagation, seismo-acoustic emission, animal behavior. The main purpose is to inform the authorities about risk situation and update hazard scenarios. The radon concentration monitoring is continuously with 1 hour or 3 hours sample rate in locations near to faults in an active seismic zone characterized by intermediate depth earthquakes. Trigger algorithms include standard deviation, mean and derivative methods. We correlate radon concentration measurements with humidity, temperature and atmospheric pressure from the same equipment. In few stations we have meteorological information, too. Sometime the radon concentration has very high variations (maxim 4535 Bq/m3 from 106 Bq/m3) in short time (1 - 2 days) without being accompanied by an important earthquake. Generally the cause is the high humidity that could be generated by tectonic stress. Correlation with seismicity needs information from minimum 6 month in our case. For 10605 hours, 618 earthquakes with maxim magnitude 4.9 R, we have got radon average 38 Bq/m3 and exposure 408111 Bqh/m3 in one station. In two cases we have correlation between seismicity and radon concentration. In other one we recorded high variation because the location was in an area with multiple faults and a river. Radon can be a seismic precursor but only in a multidisciplinary network. The anomalies for short or long period of

  13. Exalting in atmospheric tides as earthquake precursor

    Directory of Open Access Journals (Sweden)

    P. F. Biagi

    2003-01-01

    Full Text Available During February–March 1998, we observed a significant increase (6–8 dB in the electric field of the CZE (f = 270 kHz, Czech Republic broadcasting station at a site named AS and located in central Italy. On 13 March 1998 an earthquake (M = 5.2 occurred in Slovenia, starting a strong seismic crisis (M = 6.0 on 12 April, M = 5.1 on 6 May. The distances of the epicentres from the radio receiver were over 400 km, but the epicentres are located in a zone that is in the middle of the CZE-AS path. Previously, we advanced the hypothesis that the increase of radio-signal electric field detected could be a precursor of the Slovenia seismic crisis. At the purpose to precise the connection between this radio anomaly and the preparatory phase of the earthquakes, we analysed in detail the data collected. At first we carried out a FFT on the data and clear harmonic components with period 0.5d, 1d, 14d, 28d and 365d were revealed. These periods are characteristic of gravity tides and therefore, it seems reasonable to consider the previous harmonics in the electric field of the radio signal as components related to tides of the atmosphere, assuming as tides of the atmosphere only the linear action of gravity tides on atmosphere. Then, we carried out band pass filters on our data and we discovered that the February–March 1998 increase is mainly related to an exalting of the harmonics with period 0.5d, 1d, 14d and 28d, i.e. of the (semimonthly and (semidiurnal atmospheric tidal components in the radio signal. Supposing that this exalting is produced by a corresponding exalting of the atmospheric tides we propose a model able to explain the production of such an effect during the preparatory phase of the Slovenia earthquakes.

  14. Algoritmy pro umělou inteligenci

    OpenAIRE

    PETRŽELKA, Jan

    2007-01-01

    Tato diplomová práce se zabývá algoritmy používanými v oblasti umělé inteligence, konkrétně se jedná o algoritmy popsané v knize Artificial Inteligence: A Modern Approach autorů Russela a Norviga a jejich implementaci v jazyce Squeak Smalltalk. Je kladen důraz na objektově orientovaný přístup, který vyplývá z podstaty jazyka Smalltalk. Zdrojem jsou kromě popisů algoritmů v pseudokódu přímo v knize také existující implementace v jazycích Lisp, Python a Java. Tato práce se věnuje algoritmům pro...

  15. Neruda e Drummond: um olhar sobre Stalingrado

    Directory of Open Access Journals (Sweden)

    Moacir Lopes de Camargos

    2015-07-01

    Full Text Available Este artigo tem por objetivo promover uma aproximação entre dois expoentes da lírica latino-americana do século XX, a saber: Pablo Neruda e Carlos Drummond de Andrade, a partir da análise dos poemas Canto a Stalingrado (1942 e Carta a Stalingrado (1943. Apresentaremos a visão histórica desses poetas sobre a Batalha de Stalingrado, considerada um dos principais eventos da Segunda Guerra Mundial. Ademais, será abordada a questão do engajamento político, que envolve a produção poética dos referidos autores.

  16. Plágio : um problema forense

    OpenAIRE

    Sousa-Silva, Rui; Abreu, Bruna Batista

    2016-01-01

    Nas últimas décadas, o plágio tem sido perspetivado como um problemagrave nas mais diversas esferas sociais e prossionais, da academia até à justiça,com consequências sérias. Importa, por isso, questionar o papel desempenhadopela linguística forense nestes casos. Este artigo começa por contextualizar a problemáticado plágio, em geral, e do plágio académico, em particular. Tomandocomo exemplo o caso do Reino Unido, aborda a relevância das políticas de prevençãoe combate ao plágio e a sua aplic...

  17. Cromomicose cerebral: registro de um caso

    Directory of Open Access Journals (Sweden)

    Luciano de Souza Queiroz

    1979-09-01

    Full Text Available As lesões cerebrais por fungos pigmentados são excepcionais. Os autores apresentam um caso de cromomicose do sistema nervoso central, em paciente de 59 anos. O quadro clínico iniciou-se por cefaléias e hemiparesia esquerda, seguida por meningite e síndrome de hipertensão intracraniana, totalizando uma evolução de nove meses. A neerópsia revelou abcesso encapsulado nos núcleos basais à direita e leptomeningite crônica de predomínio na base do encéfalo. Em ambas as localizações foram demonstrados numerosos fungos de cor castanha, em forma arredondada ou em hifas septadas. Discutem-se as dificuldades diagnosticas desta neuromicose.

  18. Hipomelanose de Ito - relato de um caso

    Directory of Open Access Journals (Sweden)

    Adriana S. de Almeida

    2001-02-01

    Full Text Available Objetivo: Os autores têm como objetivo relatar um caso de hipomelanose de Ito (HI, uma síndrome neurocutânea rara, com alterações neurológicas e cromossômicas associadas ao comprometimento cutâneo e pneumonias de repetição. Relato do caso: Este relato é referente a um paciente masculino, 1 ano e 11 meses, internado no Hospital Universitário São Vicente de Paulo por broncopneumonia bilateral. Ao exame foram observadas máculas hipocrômicas na pele compatíveis com HI, além de atraso do desenvolvimento neuropsicomotor. O paciente foi submetido à biópsia incisional de pele das lesões do abdômen, eletroencefalograma, ressonância magnética e estudo citogenético. Resultados: Os exames histológico e imunoistoquímico evidenciaram ausência de melanina e diminuição de melanócitos em áreas focais da epiderme, respectivamente. O eletroencefalograma apresentou disfunção córtico-subcortical difusa. A ressonância magnética do encéfalo foi compatível com cisto aracnoídeo em região temporal. O cariótipo evidenciou mosaicismo cromossômico com uma linhagem normal (46,XY e uma linhagem celular que apresentava deleção intersticial nas bandas 22.2 - 24.2 do braço longo do cromossomo 10 (25%. Conclusões: Os autores, com o presente estudo, destacam a importância das lesões de pele na definição etiológica das desordens neuropediátricas.

  19. Search for precursor eruptions among Type IIb supernovae

    CERN Document Server

    Strotjohann, Nora L; Gal-Yam, Avishay; Sullivan, Mark; Kulkarni, Shrinivas R; Shaviv, Nir J; Fremling, Christoffer; Kasliwal, Mansi M; Nugent, Peter E; Cao, Yi; Arcavi, Iair; Sollerman, Jesper; Filippenko, Alexei V; Yaron, Ofer; Laher, Russ; Surace, Jason

    2015-01-01

    The progenitor stars of several Type IIb supernovae (SNe) show indications for extended hydrogen envelopes. These envelopes might be the outcome of luminous energetic pre-explosion events, so-called precursor eruptions. We use the Palomar Transient Factory (PTF) pre-explosion observations of a sample of 27 nearby Type IIb SNe to look for such precursors during the final years prior to the SN explosion. No precursors are found when combining the observations in 15-day bins, and we calculate the absolute-magnitude-dependent upper limit on the precursor rate. At the 90% confidence level, Type IIb SNe have on average $<0.86$ precursors as bright as absolute $R$-band magnitude $-14$ in the final 3.5 years before the explosion and $<0.56$ events over the final year. In contrast, precursors among SNe IIn have a $\\gtrsim 5$ times higher rate. The kinetic energy required to unbind a low-mass stellar envelope is comparable to the radiated energy of a few-weeks-long precursor which would be detectable for the clos...

  20. Clustering chlorine reactivity of haloacetic acid precursors in inland lakes.

    Science.gov (United States)

    Zeng, Teng; Arnold, William A

    2014-01-01

    Dissolved organic matter (DOM) represents the major pool of organic precursors for harmful disinfection byproducts, such as haloacetic acids (HAAs), formed during drinking water chlorination, but much of it remains molecularly uncharacterized. Knowledge of model precursors is thus a prerequisite for understanding the more complex whole water DOM. The utility of HAA formation potential data from model DOM precursors, however, is limited due to the lack of comparability to water samples. In this study, the formation kinetics of dichloroacetic acid (DCAA) and trichloroacetic acid (TCAA), the two predominant HAA species, were delineated upon chlorination of seventeen model DOM precursors and sixty-eight inland lake water samples collected from the Upper Midwest region of the United States. Of particular interest was the finding that the DCAA and TCAA formation rate constants could be grouped into four statistically distinct clusters reflecting the core structural features of model DOM precursors (i.e., non-β-diketone aliphatics, β-diketone aliphatics, non-β-diketone phenolics, and β-diketone phenolics). A comparative approach built upon hierarchical cluster analysis was developed to gain further insight into the chlorine reactivity patterns of HAA precursors in inland lake waters as defined by the relative proximity to four model precursor clusters. This work highlights the potential for implementing an integrated kinetic-clustering approach to constrain the chlorine reactivity of DOM in source waters.

  1. The Advanced Light Source: A new 1.5 GeV synchrotron radiation facility at the Lawrence Berkeley Laboratory

    International Nuclear Information System (INIS)

    The Advanced Light Source (ALS), presently under construction at the Lawrence Berkeley Laboratory, will be the world's brightest synchrotron-radiation source of ultraviolet and soft x-ray photons when it opens its doors to users in April 1993. The ALS is a third-generation source that is based on a low-emittance electron storage ring, optimized for operation at 1.5 GeV, with long straight sections for insertion devices. Its naturally short pulses are ideal for time-resolved measurements. Undulators will produce high-brightness beams from below 10 eV to above 2 keV; wigglers will produce high fluxes of harder x-rays to energies above 10 keV. The ALS will support an extensive research program in a broad spectrum of scientific and technological areas. The high brightness will open new areas of research in the materials sciences, such as spatially resolved spectroscopy (spectromicroscopy). Biological applications will include x-ray microscopy with element-specific sensitivity in the water window of the spectrum where water is much more transparent than protein. The ALS will be an excellent research tool for atomic physics and chemistry because the high flux will allow measurements to be made with tenuous gas-phase targets. Undulator radiation can excite the K shell of elements up to silicon and the L shell of elements up to krypton, and wiggler radiation can excite the L shell of nearly every element. The ALS will operate as a national user facility; interested scientists are encouraged to contact the ALS Scientific Program Coordinator to explore their scientific and technological research interests

  2. Out-of-band exposure characterization with the SEMATECH Berkeley 0.3-NA microfield exposure tool

    Energy Technology Data Exchange (ETDEWEB)

    George, Simi A.; Nauleau, Patrick; Rekawa, Senajith; Gullikson, Eric; Kemp, Charles D.

    2009-02-23

    For the commercialization of extreme ultraviolet lithography (EUVL), discharge or laser produced, pulsed plasma light sources are being considered. These sources are known to emit into a broad range of wavelengths that are collectively referred to as the out-of-band (OOB) radiation by lithographers. Multilayer EUV optics reflect OOB radiation emitted by the EUV sources onto the wafer plane resulting in unwanted background exposure of the resist (flare) and reduced image contrast. The reflectivity of multilayer optics at the target wavelength of 13.5 nm is comparable to that of their reflectivity in the deep ultraviolet (DUV) and UV regions from 100-350 nm. The aromatic molecular backbones of many of the resists used for EUV are equally absorptive at specific DUV wavelengths as well. In order to study the effect of these wavelengths on imaging performance in a real system, we are in the process of integrating a DUV source into the SEMATECH Berkeley 0.3-NA Microfield Exposure Tool (MET). The MET plays an active role in advanced research in resist and mask development for EUVL and as such, we will utilize this system to systematically evaluate the imaging impact of DUV wavelengths in a EUV system. In this paper, we present the optical design for the new DUV component and the simulation-based imaging results predicting the potential impact of OOB based on known resist, mask, and multilayer conditions. It should be noted that because the projection optics work equally well as imaging optics at DUV wavelengths, the OOB radiation cannot be treated simply as uniform background or DC flare.

  3. Um estudo empírico de um sistema de reconhecimento facial utilizando o classificador KNN

    Directory of Open Access Journals (Sweden)

    Fabio Abrantes Diniz

    2016-06-01

    Full Text Available Neste artigo, apresenta-se um estudo empírico de otimização das taxas de acurácias resultantes de um sistema de reconhecimento facial baseado nas técnicas Eigenfaces e K-Nearest Neighbors. Foram investigadas as seguintes variáveis: imagens com três dimensões distintas, número de características (Eigenfaces, valores de k da técnica K-Nearest Neighbors e três medidas de distância (euclidiana, Manhattan e euclidiana normalizada. Os estudos foram importantes para entender empiricamente quais parâmetros são os mais relevantes para as técnicas analisadas e que resultam em melhores taxas de acurácias de reconhecimento facial. Os resultados dos experimentos comprovaram que as imagens com dimensões 12x9 pixels produzem as melhores taxas de acurácias de reconhecimento facial, combinando com a medida de distância euclidiana normalizada e um número de Eigenfaces igual a vinte.

  4. Biological Indicators in Studies of Earthquake Precursors

    Science.gov (United States)

    Sidorin, A. Ya.; Deshcherevskii, A. V.

    2012-04-01

    Time series of data on variations in the electric activity (EA) of four species of weakly electric fish Gnathonemus leopoldianus and moving activity (MA) of two cat-fishes Hoplosternum thoracatum and two groups of Columbian cockroaches Blaberus craniifer were analyzed. The observations were carried out in the Garm region of Tajikistan within the frameworks of the experiments aimed at searching for earthquake precursors. An automatic recording system continuously recorded EA and DA over a period of several years. Hourly means EA and MA values were processed. Approximately 100 different parameters were calculated on the basis of six initial EA and MA time series, which characterize different variations in the EA and DA structure: amplitude of the signal and fluctuations of activity, parameters of diurnal rhythms, correlated changes in the activity of various biological indicators, and others. A detailed analysis of the statistical structure of the total array of parametric time series obtained in the experiment showed that the behavior of all animals shows a strong temporal variability. All calculated parameters are unstable and subject to frequent changes. A comparison of the data obtained with seismicity allow us to make the following conclusions: (1) The structure of variations in the studied parameters is represented by flicker noise or even a more complex process with permanent changes in its characteristics. Significant statistics are required to prove the cause-and-effect relationship of the specific features of such time series with seismicity. (2) The calculation of the reconstruction statistics in the EA and MA series structure demonstrated an increase in their frequency in the last hours or a few days before the earthquake if the hypocenter distance is comparable to the source size. Sufficiently dramatic anomalies in the behavior of catfishes and cockroaches (changes in the amplitude of activity variation, distortions of diurnal rhythms, increase in the

  5. The ISO 170um Luminosity Function of Galaxies

    CERN Document Server

    Takeuchi, T T; Dole, H; Dennefeld, M; Lagache, G; Puget, J L; Takeuchi, Tsutomu T.; Ishii, Takako T.; Dole, Herve; Dennefeld, Michel; Lagache, Guilaine; Puget, Jean-Loup

    2005-01-01

    We constructed a local luminosity function (LF) of galaxies using a flux-limited sample (S_170 > 0.195Jy) of 55 galaxies at z < 0.3 taken from the ISO FIRBACK survey at 170um. The overall shape of the 170-um LF is found to be different from that of the total 60-um LF (Takeuchi et al. 2003): the bright end of the LF declines more steeply than that of the 60-um LF. This behavior is quantitatively similar to the LF of the cool subsample of the IRAS PSCz galaxies. We also estimated the strength of the evolution of the LF by assuming the pure luminosity evolution (PLE): L(z) \\propto (1+z)^Q. We obtained Q=5.0^{+2.5}_{-0.5} which is similar to the value obtained by recent Spitzer observations, in spite of the limited sample size. Then, integrating over the 170-um LF, we obtained the local luminosity density at 170um, \\rho_L(170um). A direct integration of the LF gives \\rho_L(170um) = 1.1 \\times 10^8 h Lsun Mpc^{-3}, whilst if we assume a strong PLE with Q=5, the value is 5.2 \\times 10^7 h Lsun Mpc^{-3}. This is ...

  6. Berkeley Lighting Cone

    Energy Technology Data Exchange (ETDEWEB)

    Lask, Kathleen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gadgil, Ashok [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2016-10-24

    A lighting cone is a simple metal cone placed on the fuel bed of a stove during ignition to act as a chimney, increasing the draft through the fuel bed. Many stoves tend to be difficult to light due to poor draft through the fuel bed, so lighting cones are used in various parts of the world as an inexpensive accessory to help with ignition.

  7. Berkeley Proton Linear Accelerator

    Science.gov (United States)

    Alvarez, L. W.; Bradner, H.; Franck, J.; Gordon, H.; Gow, J. D.; Marshall, L. C.; Oppenheimer, F. F.; Panofsky, W. K. H.; Richman, C.; Woodyard, J. R.

    1953-10-13

    A linear accelerator, which increases the energy of protons from a 4 Mev Van de Graaff injector, to a final energy of 31.5 Mev, has been constructed. The accelerator consists of a cavity 40 feet long and 39 inches in diameter, excited at resonance in a longitudinal electric mode with a radio-frequency power of about 2.2 x 10{sup 6} watts peak at 202.5 mc. Acceleration is made possible by the introduction of 46 axial "drift tubes" into the cavity, which is designed such that the particles traverse the distance between the centers of successive tubes in one cycle of the r.f. power. The protons are longitudinally stable as in the synchrotron, and are stabilized transversely by the action of converging fields produced by focusing grids. The electrical cavity is constructed like an inverted airplane fuselage and is supported in a vacuum tank. Power is supplied by 9 high powered oscillators fed from a pulse generator of the artificial transmission line type.

  8. "Poliedro é um sólido, correto?":um estudo com graduandos interagindo em um chat sobre a definição de poliedro

    Directory of Open Access Journals (Sweden)

    Rodrigo Zuza Nieto

    2013-01-01

    Full Text Available Na pesquisa educacional, são escassos os estudos que analisam a construção de conceitos geométricos mediante interações à distância. Essa investigação está focada no entendimento de futuros professores sobre a definição de poliedro. O artigo é fruto de uma pesquisa que analisa interações em ambientes virtuais de aprendizagem. Apresentaremos, resumidamente, o cenário que foi elaborado para ser um curso sobre poliedros estrelados e, posteriormente, analisaremos as interações em um de seus espaços: o chat. A investigação sublinha que a análise em um chat deve movimentar-se de uma visão global para uma visão focada nas reflexões individuais/coletivas. O chat mostrou ser um cenário que oportunizou, aos graduandos, refletirem sobre a definição de poliedros em três âmbitos: um no contexto dos sólidos geométricos, um focado nos seus elementos (faces, arestas e vértices e outro centrado no número de dimensões.

  9. Precursor Parameter Identification for Insulated Gate Bipolar Transistor (IGBT) Prognostics

    Data.gov (United States)

    National Aeronautics and Space Administration — Precursor parameters have been identified to enable development of a prognostic approach for insulated gate bipolar transistors (IGBT). The IGBT were subjected to...

  10. Malic acid assisted precursor route to hierarchical structured nickel oxide

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Haizhen [Zhejiang California International Nanosystems Institute, Zhejiang University, Hangzhou, Zhejiang (China); Qian, Yitai [Hefei National Laboratory for Physical Science at Microscale, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui (China)

    2010-05-15

    A novel malic acid assisted precursor route to prepare NiO materials with novel hierarchical structures has been investigated in this work. The Ni-based precursors can be synthesized by a malic acid-assisted hydrothermal route, which have been characterized by powder X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM), thermogravimetric analysis (TGA). NiO materials can be prepared via the thermal treatment of the precursor in ambient atmosphere. The XRD, SEM, Energy dispersive X-ray spectroscopy (EDS) and UV-Vis spectroscopy of the NiO materials were also examined. The effects of the reaction conditions, such as the reaction temperature, the quantity of the raw materials on the morphologies of the precursors were discussed, which indicates that it is an effective method to synthesize NiO materials with different hierarchical structures. (copyright 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  11. Um modelo evolucionário setorial

    Directory of Open Access Journals (Sweden)

    Mario L. Possas

    2001-09-01

    Full Text Available Este artigo apresenta um modelo evolucionário setorial de simulação que combina microfundamentos neo-schumpeterianos e pós-keynesianos e expõe alguns resultados preliminares das primeiras simulações. Estes resultados apontam, quanto a distintas condições do ambiente de mercado: o efeito positivo da taxa de crescimento da produtividade na fronteira tecnológica sobre a concentração de mercado; o efeito ambíguo do aprendizado, capaz de produzir um lock-in de firmas inovadoras pioneiras em tecnologias que se tornam eventualmente obsoletas; o efeito "anti-seletivo" de taxas de juros muito elevadas, endividando e prejudicando o esforço de investimento e o sucesso competitivo das inovadoras em benefício das imitadoras. Quanto à simulação das estratégias de preços, constatou-se: a maior seletividade de estratégias em que as firmas inovadoras dão mais peso ao mark-up desejado, gerando maior concentração de mercado, efeito que é atenuado pelo crescimento da demanda e pelo aprendizado; a importância, para a sobrevivência de empresas menos inovadoras, do feedback do desempenho competitivo sobre o mark-up desejado e o efetivo, aumentando a adaptabilidade das empresas às condições de seleção do mercado.This paper presents a sectoral evolutionary simulation model combining neo-Schumpeterian and Post-Keynesian microfoundations, and exhibits some preliminary results. As to different market environment conditions, the simulations suggest: a positive effect of productivity growth of the technological frontier on market concentration; an ambiguous result of "learning by doing", from which innovation leaders may be found "locked in" new technologies that eventually become obsolete; a "counter-selective" effect of very high interest rates which may increase innovators indebtedness to the extent of impairing their investment efforts and competitive success as compared to some imitators. As to different price strategies, major findings

  12. Para um perfil do idoso-andarilho

    Directory of Open Access Journals (Sweden)

    Claudia Lysia de Oliveira Araújo

    2012-01-01

    Full Text Available O termo envelhecimento é frequentemente empregado para descrever as mudanças morfofuncionais que ocorrem ao longo da vida humana, após a maturação sexual e que, progressivamente, comprometem a capacidade de resposta dos indivíduos ao estresse ambiental e à manutenção da homeostasia. Na condição de pessoas em envelhecimento avançado e de vida fragilizada, são encontrados muitos idosos-andarilhos por estradas e ruas das cidades brasileiras. Definimos aqui andarilho como a pessoa que vive fora do lar, em um cotidiano muito simples, miserável até, afastado de relações familiares e sociais mais próximas, distanciados do sentido de uma vida dita normal. A falta deste sentido de vida, a que se alia o preconceito da sociedade, têm sido fatores que levam à estigmatização desses idosos abandonados, fazendo-os a acreditar que a rua é o único lugar que lhes resta para viver. O objetivo deste estudo foi conhecer os motivos que conduzem um idoso a se tornar andarilho, tendo sido realizado nos albergues das cidades do Vale do Paraíba, no Estado de São Paulo. O universo desta experiência foram alguns idosos sem moradia, independentemente de gênero. Identificamos, neste estudo, os idosos encontrados não por seus nomes reais, mas por meio da denominação dada a pedras preciosas. Eles relataram ter profissão, embora vivam sós, perambulando pelas ruas das citadas regiões urbanas. Quanto aos problemas de saúde, os idosos aqui entrevistados referiram alguma patologia, ainda que nenhum deles fizesse tratamento ou visitasse médico regularmente, por não disporem de documentos. Os relatos desses idosos-andarilhos apontam para uma condição de sobrevivência fragilizada, comprometida por se tornarem muito vulneráveis, susceptíveis a agressões externas, o que agudiza cada vez mais sua exclusão familiar e social. Por fim, verifica-se que eles ainda sonham em voltar ao lar e recomeçar a vida ao lado da própria família.

  13. Improved Single-Source Precursors for Solar-Cell Absorbers

    Science.gov (United States)

    Banger, Kulbinder K.; Harris, Jerry; Hepp, Aloysius

    2007-01-01

    Improved single-source precursor compounds have been invented for use in spray chemical vapor deposition (spray CVD) of chalcopyrite semiconductor absorber layers of thin-film cells. A "single-source precursor compound" is a single molecular compound that contains all the required elements, which when used under the spray CVD conditions, thermally decomposes to form CuIn(x)Ga(1-x)S(y)Se(2-y).

  14. Precursors of Personality Disorders in Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Merve Cikili Uytun

    2015-12-01

    Full Text Available Personality disorders are common psychiatric disorders in community that cause substantial disruption of functionality. Current diagnostic systems do not include classification of personality disorders in children. However, in recent years there has been an increasing interest in investigation of personality traits and disorders at childhood and adolescence as a precursor of adult personality disorders. The aim of this article was to review the precursors of personality disorders at childhood and adolescence

  15. Intraspinal transplantation of mouse and human neural precursor cells

    OpenAIRE

    Weinger, Jason G.; Chen, Lu; Coleman, Ronald; Leang, Ronika; Plaisted, Warren C.; Loring, Jeanne F.; Lane, Thomas E

    2013-01-01

    This unit describes the preparation and transplantation of human neural precursor cells (hNPCs) and mouse neural precursor cells (mNPCs) into the thoracic region of the mouse spinal cord. The techniques in this unit also describe how to prepare the mouse for surgery by performing a laminectomy to expose the spinal cord for transplantation. Here we show NPCs genetically labeled with eGFP transplanted into the spinal cord of a mouse following viralmediated demyelination can efficiently be detec...

  16. Precursors for the polymer-assisted deposition of films

    Science.gov (United States)

    McCleskey, Thomas M.; Burrell, Anthony K.; Jia, Quanxi; Lin, Yuan

    2013-09-10

    A polymer assisted deposition process for deposition of metal oxide films is presented. The process includes solutions of one or more metal precursor and soluble polymers having binding properties for the one or more metal precursor. After a coating operation, the resultant coating is heated at high temperatures to yield metal oxide films. Such films can be epitaxial in structure and can be of optical quality. The process can be organic solvent-free.

  17. Secretion and processing of insulin precursors in yeast.

    OpenAIRE

    Thim, L.; Hansen, M T; Norris, K; Hoegh, I; Boel, E; Forstrom, J; Ammerer, G; Fiil, N P

    1986-01-01

    A series of dibasic insulin precursors including proinsulin was expressed and secreted from Saccharomyces cerevisiae. Recombinant plasmids were constructed to encode fusion proteins consisting of a modified mating factor alpha 1 leader sequence and an insulin precursor. The leader sequence serves to direct the fusion protein into the secretory pathway of the cell and to expose it to the Lys-Arg processing enzyme system. The secreted peptides were purified from the fermentation broth and chara...

  18. Structure and gene organization of bovine neuromedin K precursor.

    OpenAIRE

    Kotani, H.; Hoshimaru, M; Nawa, H; Nakanishi, S.

    1986-01-01

    cDNA and genomic DNA clones for the precursor of a mammalian neuropeptide tachykinin, neuromedin K, have been isolated and characterized by molecular cloning and sequence analysis. The deduced amino acid sequence indicates that the bovine neuromedin K precursor (preprotachykinin B) consists of 126 amino acid residues including a putative signal peptide. There are two preprotachykinin B mRNAs that differ only at the 5' extremity of the untranslated regions. The major mRNA species is encoded by...

  19. Detection of hydrogeochemical seismic precursors by a statistical learning model

    Directory of Open Access Journals (Sweden)

    L. Castellana

    2008-11-01

    Full Text Available The problem of detecting the occurrence of an earthquake precursor is faced in the general framework of the statistical learning theory. The aim of this work is both to build models able to detect seismic precursors from time series of different geochemical signals and to provide an estimate of number of false positives. The model we used is k-Nearest-Neighbor classifier for discriminating "no-disturbed signal", "seismic precursor" and "co-post seismic precursor" in time series relative to thirteen different hydrogeochemical parameters collected in water samples from a natural spring in Kamchachta (Russia peninsula. The measurements collected are ion content (Na, Cl, Ca, HCO3, H3BO3, parameters (pH, Q, T and gases (N2, CO2, CH4, O2, Ag. The classification error is measured by Leave-K-Out-Cross-Validation procedure. Our study shows that the most discriminative ions for detecting seismic precursors are Cl and Na having an error rates of 15%. Moreover, the most discriminative parameters and gases are Q and CH4 respectively, with error rate of 21%. The ions result the most informative hydrogeochemicals for detecting seismic precursors due to the peculiarities of the mechanisms involved in earthquake preparation. Finally we show that the information collected some month before the event under analysis are necessary to improve the classification accuracy.

  20. Risk Assessment of Infrastructure System of Systems with Precursor Analysis.

    Science.gov (United States)

    Guo, Zhenyu; Haimes, Yacov Y

    2016-08-01

    Physical infrastructure systems are commonly composed of interconnected and interdependent subsystems, which in their essence constitute system of systems (S-o-S). System owners and policy researchers need tools to foresee potential emergent forced changes and to understand their impact so that effective risk management strategies can be developed. We develop a systemic framework for precursor analysis to support the design of an effective and efficient precursor monitoring and decision support system with the ability to (i) identify and prioritize indicators of evolving risks of system failure; and (ii) evaluate uncertainties in precursor analysis to support informed and rational decision making. This integrated precursor analysis framework is comprised of three processes: precursor identification, prioritization, and evaluation. We use an example of a highway bridge S-o-S to demonstrate the theories and methodologies of the framework. Bridge maintenance processes involve many interconnected and interdependent functional subsystems and decision-making entities and bridge failure can have broad social and economic consequences. The precursor analysis framework, which constitutes an essential part of risk analysis, examines the impact of various bridge inspection and maintenance scenarios. It enables policy researchers and analysts who are seeking a risk perspective on bridge infrastructure in a policy setting to develop more risk informed policies and create guidelines to efficiently allocate limited risk management resources and mitigate severe consequences resulting from bridge failures. PMID:27575259

  1. Role of neural precursor cells in promoting repair following stroke

    Institute of Scientific and Technical Information of China (English)

    Pooya DIBAJNIA; Cindi M MORSHEAD

    2013-01-01

    Stem cell-based therapies for the treatment of stroke have received considerable attention.Two broad approaches to stem cell-based therapies have been taken:the transplantation of exogenous stem cells,and the activation of endogenous neural stem and progenitor cells (together termed neural precursors).Studies examining the transplantation of exogenous cells have demonstrated that neural stem and progenitor cells lead to the most clinically promising results.Endogenous activation of neural precursors has also been explored based on the fact that resident precursor cells have the inherent capacity to proliferate,migrate and differentiate into mature neurons in the uninjured adult brain.Studies have revealed that these neural precursor cell behaviours can be activated following stroke,whereby neural precursors will expand in number,migrate to the infarct site and differentiate into neurons.However,this innate response is insufficient to lead to functional recovery,making it necessary to enhance the activation of endogenous precursors to promote tissue repair and functional recovery.Herein we will discuss the current state of the stem cell-based approaches with a focus on endogenous repair to treat the stroke injured brain.

  2. Elements of the tsunami precursors' detection physics

    Science.gov (United States)

    Novik, Oleg; Ruzhin, Yuri; Ershov, Sergey; Volgin, Max; Smirnov, Fedor

    ionosphere from the buoy, balloon and satellite complexes. The balloon and buoy complexes will transmit data to a shore station over satellite link. The frequency ranges and sensitivity thresholds of all of the sensors of the LOAMS will be adapted to the characteristics of expected seismic signals according to the numerical research above. Computational methods and statistical analysis (e.g. seismic changes of coherence of spatially distributed sensors of different nature) of the recorded multidimensional time series will be used for prognostic interpretation. The multilevel recordings will provide a stable noise (e.g. ionosphere Pc pulsations, hard sea, industry) and seismic event detection. An intensive heat flow typical for tectonically active lithosphere zones may be considered as an energy source for advanced modifications of the LOAMS. The latter may be used as a warning system for continental and marine technologies, e.g. a sea bottom geothermal energy production. Indeed, seismic distraction of the nuclear power station Fukushima I demonstrates that similar technology hardly is able to solve the energy problems in seismically active regions. On the other hand, the LOAMS may be considered as a scientific observatory for development of the seaquake/tsunami precursor physics, i.e. seismo-hydro-electromagnetics.

  3. Um encontro de mulheres: dar à luz

    Directory of Open Access Journals (Sweden)

    Maysa Luduvice Gomes

    1998-09-01

    Full Text Available Este trabalho analisa a relação que se estabelece entre a mulher durante o processo de parturição e a enfermeira obstetra, mulher e agente institucional. Discute-se como a experência de submissão é vivenciada pela mulher, sujeito de um processo anátomo-fisiológico, e a forma pela qual se expressa o exercício do poder e dominação da instituição que a enfermeira representa sobre a mulher usuária. Expõe-se a submissão da mulher ao serviço e sua expectativa com relação ao momento do parto, ao medo da dor e aos maus tratos. Analisa-se o poder sutil e educado exercido pela enfermeira sobre a parturiente, mostrando também que é uma mulher que cuida de outra, expressando sua subjetividade, a qual é sufocada pelo padrão da racionalidade científica moderna. A abordagem foi qualitativa e os dados, coletados através da observação participante em entrevista semi-estruturada, foram analisados dialeticamente.

  4. Abner Vicentini: um pioneiro da Biblioteconomia brasileira

    Directory of Open Access Journals (Sweden)

    Murilo Bastos Cunha

    2014-05-01

    Full Text Available Este ensaio biobibliográfico analisa a trajetória profissional do bibliotecário Abner Vicentini (23/08/1929 – 9/08/1976. Dentre vários cargos ocupados, Abner Vicentini foi presidente da Associação Paulista de Bibliotecários (1958-1961; professor de Biblioteconomia na Universidade de Brasília (1964-1971; conselheiro da Federação Internacional de Documentação; consultor da FAO para a implantação da Biblioteca Nacional da Agricultura e do Sistema Nacional de Informação e Documentação Agrícola (1975-1976. Como diretor na área de bibliotecas, Vicentini passou pela seguinte trajetória: Instituto Tecnológico de Aeronáutica (1952-1953, Centro Tecnológico da Aeronáutica (1954-1963, Universidade de Brasília (1964-1971, Ministério das Minas e Energia (1972-1975. Abner Vicentini foi ainda, um grande divulgador da Classificação Decimal Universal e editor da primeira edição brasileira do Anglo-American Cataloging Rules (AACR-1, lançada em 1969

  5. O plurilinguismo: um trunfo? = Plurilingualism: an asset?

    Directory of Open Access Journals (Sweden)

    Pinto, Maria da Graça Castro

    2013-01-01

    Full Text Available O fenómeno da globalização e a facilidade com que hoje em dia se circula, virtualmente ou presencialmente, na “aldeia global” que constitui o nosso planeta justificam como nunca antes a existência de um contacto mais próximo entre povos e consequentemente entre falantes de diferentes línguas, que são igualmente portadores das mais variadas culturas. Tendo presente o referido enquadramento, este texto aborda alguns termos de uso cada vez mais frequente nos nossos dias (aquisição, aprendizagem, bilinguismo, multilinguismo, segunda língua, língua estrangeira, terceira língua, plurilinguismo, equaciona a sua abrangência e chama a atenção para o que cada termo pode ocultar para lá do significado que lhe pode ser mais facilmente atribuído. Procura ainda este texto responder, com base numa perspetiva histórica, ao título proposto, recorrendo contudo também a achegas provindas da área cognitiva com o objetivo de problematizar uma pergunta à primeira vista de resposta óbvia e afirmativa

  6. Charles Darwin: um observador do desenvolvimento humano

    Directory of Open Access Journals (Sweden)

    Eloisa Helena Rubello Valler Celeri

    2010-12-01

    Full Text Available Os autores traduzem, pela primeira vez para o português, o artigo de Charles Darwin "A Biographical Sketch of an Infant", publicado no periódico Mind em julho de 1877. Utilizando anotações de observações do desenvolvimento de seus filhos, especialmente de seu filho mais velho William Erasmus (Doddy, Darwin descreve e estuda, a partir de seu enfoque naturalista, o filhote humano, narrando os primeiros indicativos comportamentais de emoções tais como raiva e medo, curiosidade e senso moral, o brincar e o prazer envolvido nesta atividade, a capacidade de imitação e os primeiros indícios daquilo que hoje conhecemos como "teoria da mente". Colocando-se questões sobre as capacidades do bebê, como eles aprendem e como se comunicam e levantando hipóteses sobre possíveis significados de certos comportamentos, questões ainda hoje fundamentais para o estudo do desenvolvimento humano, Darwin mostra-se também um pioneiro no estudo do bebê e da criança pequena, numa época na qual as capacidades dos bebês eram extremamente subestimadas e desconsideradas.

  7. Predicting Solar Cycle 24 Using a Geomagnetic Precursor Pair

    Science.gov (United States)

    Pesnell, W. Dean

    2014-01-01

    We describe using Ap and F(10.7) as a geomagnetic-precursor pair to predict the amplitude of Solar Cycle 24. The precursor is created by using F(10.7) to remove the direct solar-activity component of Ap. Four peaks are seen in the precursor function during the decline of Solar Cycle 23. A recurrence index that is generated by a local correlation of Ap is then used to determine which peak is the correct precursor. The earliest peak is the most prominent but coincides with high levels of non-recurrent solar activity associated with the intense solar activity of October and November 2003. The second and third peaks coincide with some recurrent activity on the Sun and show that a weak cycle precursor closely following a period of strong solar activity may be difficult to resolve. A fourth peak, which appears in early 2008 and has recurrent activity similar to precursors of earlier solar cycles, appears to be the "true" precursor peak for Solar Cycle 24 and predicts the smallest amplitude for Solar Cycle 24. To determine the timing of peak activity it is noted that the average time between the precursor peak and the following maximum is approximately equal to 6.4 years. Hence, Solar Cycle 24 would peak during 2014. Several effects contribute to the smaller prediction when compared with other geomagnetic-precursor predictions. During Solar Cycle 23 the correlation between sunspot number and F(10.7) shows that F(10.7) is higher than the equivalent sunspot number over most of the cycle, implying that the sunspot number underestimates the solar-activity component described by F(10.7). During 2003 the correlation between aa and Ap shows that aa is 10 % higher than the value predicted from Ap, leading to an overestimate of the aa precursor for that year. However, the most important difference is the lack of recurrent activity in the first three peaks and the presence of significant recurrent activity in the fourth. While the prediction is for an amplitude of Solar Cycle 24 of

  8. Fitoterápicos: um mercado promissor

    Directory of Open Access Journals (Sweden)

    TRAUDI KLEIN

    2010-06-01

    Full Text Available

    Observa-se na Fitoterapia uma tendência de contribuição efetiva à saúde da população. Por consequência, a padronização de fitomedicamentos é um pré-requisito para a garantia da qualidade, bem como para a constância dos efeitos terapêuticos e segurança do usuário. A validação de processo analítico deve garantir, através de evidências experimentais, que o método atenda às exigências das aplicações analíticas, assegurando a confiabilidade dos resultados. Assim, os equipamentos e materiais de laboratório devem ser devidamente calibrados e o analista qualificado. As substâncias químicas de referência devem ser certificadas por compêndios oficiais, como as Farmacopeias ou por outros códigos autorizados pela legislação vigente.Tão importante quanto o desenvolvimento e validação de uma metodologia analítica é o posterior estudo de estabilidade, a fim de garantir que o produto mantenha sua qualidade durante toda vida útil. Para a obtenção de registro de um medicamento fitoterápico dentro dos padrões requeridos pela legislação faz-se necessário, portanto, a realização de diferentes testes para validação deste medicamento de forma a garantir sua segurança no uso, eficácia na utilização e qualidade do produto. Palavras-chave: Fitomedicamentos. Validação. Saúde Publica. Padronização. ABSTRACT Phytomedicines: a promising market There is an observable trend towards phytotherapy making a recognized effective contribution to public health. Consequently, the standardization of phytomedicines is a prerequisite for quality assurance and to ensure the consistency of therapeutic effects and safety of the user. Analytical method validation should ensure, through experimental testing, that the method meets the requirements of the analytical applications, ensuring the reliability of results. Thus, the equipment and laboratory materials must be properly calibrated and the analyst

  9. Criatividade e gastronomia: Um estudo exploratório

    OpenAIRE

    Ferreira, Ana Catarina

    2012-01-01

    O presente trabalho é um estudo exploratório que aborda o tema da criatividade na gastronomia, sendo um tema pioneiro e pouco trabalhado. Na teoria, a gastronomia tem um grande significado afectivo e identitário (seja a nível cultural ou a nível individual) e é uma área que acompanha o desenvolvimento das sociedades. Por outro lado, a criatividade demonstra-se como sendo uma prática complexa de processos e dinâmicas mentais, também implicando muito da identidade e da personalidade do sujeito ...

  10. Desenvolvimento de um monitor de apneia pediátrico

    OpenAIRE

    Caldeira, Gonçalo José Martins

    2009-01-01

    O trabalho apresentado tem por base o desenvolvimento de um monitor de apneia do sono pediátrico. Aborda questões ao nível da fisiologia respiratória e da mecânica pulmonar de um indivíduo. Apresenta uma proposta de desenvolvimento de um monitor de aquisição e identificação de sinais respiratórios, a fim de efectuar a detecção da apneia do sono.

  11. Medidas da umidade relativa do ar em um ambiente fechado

    OpenAIRE

    Costa Eden V.

    2003-01-01

    Umidade do ar e o vapor d'água presente na atmosfera. Neste trabalho medimos a umidade relativa do ar em um ambiente fechado onde a temperatura foi mantida constante. Nestas condições, a umidade cresce até o vapor d'água tornar-se saturado. Neste instante, a umidade é máxima. O aparato experimental utilizado consiste de recipiente fechado de vidro, higrômetro, termômetro e relógio. Trata-se, portanto, de um experimento simples, possível de ser realizado em um laboratório didático e capaz de p...

  12. Desenvolvimento de um indicador de melhoria contínua

    OpenAIRE

    Semião, Rui Miguel Santos Coelho

    2008-01-01

    O presente relatório resulta do desenvolvimento de um projecto de estágio efectuado, ao longo de nove meses, na empresa Bosch Termotecnologia SA. O objectivo deste trabalho é a definição da forma de cálculo de um indicador, que permitirá avaliar a frequência com que é produzido um grupo específico de produtos da empresa. O cálculo periódico deste indicador e, consequentemente, o seu acompanhamento irão permitir uma maior transparência no processo de planeamento de produção, ...

  13. BUSCANDO UM BIOHERBICIDA CONTRA Cyperus sp (tiririca

    Directory of Open Access Journals (Sweden)

    Cristine Benfatti Gonzalez

    2001-01-01

    Full Text Available As an alternative to conventional control of Cyperus sp (herbaceousnutsedge, with chemical products, it rises the biological control, making use of phytopathogenic microorganisms. As results of the whole production of Cercospora henningsii e Cercospora caricis by fermentation in potato-dextrose (PD liquid medium, it was observed that both species obtained the optimum growth at 36o C. C. henningsii attained the best value after a period of 72 h of fermentation and C. caricis attained it after 60 h. The field experiments, against Cyperus sp (nutsedge, with the obtained products by liquid fermentation of Cercospora sp (C. henningsii and/or C. caribaea, andwith the use of "wet chamber", proved the pathogenic potential bioherbicide of these microorganisms. = Como alternativa ao controle convencional do Cyperus sp (tiririca usando produtos químicos, surge o controle biológico, empregando-se microrganismos fitopatógenos. Como resultados da produção massal de Cercospora henningsii eCercospora caricis através de cultivo submerso em meio de cultura batata-dextrose (BD, observou-se que ambas espécies obtiveram um crescimento ótimo a 36o C, sendo que para C. henningsii se deu com 72 h de fermentação e para C. caricis com 60 h. Os experimentos de campo, bem como os de Câmara úmida, contra Cyperus sp (tiririca,com os produtos obtidos pelo cultivo submerso de Cercospora sp (C. henningsii e/ou C. caribaea, demonstraram a patogenicidade, ou seja, o potencial bioherbicida desses microrganismos.

  14. "Um vasto prazer, quieto e profundo"

    Directory of Open Access Journals (Sweden)

    Eliane Robert Moraes

    2009-01-01

    Full Text Available A descrição da tortura de um rato, no conto "A causa secreta" de Machado de Assis, pode parecer tímida se comparada às cenas de suplício narradas por Sade. Todavia, uma leitura mais atenta encontrará ali as condições essenciais para a eclosão de uma misteriosa forma de prazer que costuma estar associada à figura do "sádico". Uma tal aproximação surpreende ainda mais quando se constata que o sadismo do protagonista do conto assume contornos bem mais verossímeis do que as inconcebíveis fabulações de crueldade dos devassos do marquês. Este texto parte do confronto entre os dois autores, valendo-se do diálogo entre uma dimensão estética (o realismo e outra ética (o mal, na tentativa de propor uma interpretação do conto machadiano.The description of a mouse being tortured in Machado de Assis's short story "A causa secreta" [English translation: "The Secret Heart"] may seem timid if compared with the scenes of agony narrated by the Marquis De Sade. Nevertheless, a detailed reading will find in this short story essential conditions for the outburst of a mysterious form of pleasure that is usually associated with the image of a "sadist". A closer look might surprise the reader even more with the acknowledgement that the sadism of the protagonist takes on shapes that are more verisimilar than the inconceivable accounts of cruelty of the Marquis's dissolute characters. By means of a dialogue between an aesthetic dimension (realism and an ethic dimension (evil, this essay confronts these two authors in an attempt to propose an interpretation of Machado de Assis's short story.

  15. Subcellular Distribution of Glutathione Precursors in Arabidopsis thafiana

    Institute of Scientific and Technical Information of China (English)

    Barbara Eva Koffier; Romana Maier; Bernd Zechmann

    2011-01-01

    Glutathione is an important antioxidant and has many important functions in plant development,growth and defense.Glutathione synthesis and degradation is highly compartment-specific and relies on the subcellular availability of its precursors,cysteine,glutamate,glycine and y-glutamylcysteine especially in plastids and the cytosol which are considered as the main centers for glutathione synthesis.The availability of glutathione precursors within these cell compartments is therefore of great importance for successful plant development and defense.The aim of this study was to investigate the compartmentspecific importance of glutathione precursors in Arabidopsis thaliana.The subcellular distribution was compared between wild type plants (Col-0),plants with impaired glutathione synthesis (glutathione deficient pad2-1 mutant,wild type plants treated with buthionine sulfoximine),and one complemented line (OE3) with restored glutathione synthesis.Immunocytohistochemistry revealed that the inhibition of glutathione synthesis induced the accumulation of the glutathione precursors cysteine,glutamate and glycine in most cell compartments including plastids and the cytosol.A strong decrease could be observed in γ-glutamylcysteine (γ-EC) contents in these cell compartments.These experiments demonstrated that the inhibition of y-glutamylcysteine synthetase (GSH1) - the first enzyme of glutathione synthesis - causes a reduction of γ-EC levels and an accumulation of all other glutathione precursors within the cells.

  16. Os games digitais como um recurso cognitivo para o ensino da historia da Catalunha: um estudo de caso

    OpenAIRE

    Eguía, José Luis; Contreras, Ruth S. (Ruth Sofhía); Solano Albajés, Lluís

    2012-01-01

    Os games digitais possuem um valor educativo importante e têm sido reconhecidos pelos educadores como um rico e produtivo espaço que proporciona conteúdos de aprendizagem para os estudantes, melhorando, através dele, o desenvolvimento cognitivo do aluno. Este artigo explora as oportunidades cognitivas dos games digitais como uma ferramenta de aprendizagem e mostra um estudo de caso: o jogo de Joan de Peratallada. O objetivo desse estudo é promover o diálogo e a possível colabor...

  17. Jane Eyre de Michael Berkeley et de David Malouf : La transposition opératique d’un grand classique de la littérature anglaise Jane Eyre by Michael Berkeley and David Malouf: The Operatic Rewriting of a Great Classic English Novel

    Directory of Open Access Journals (Sweden)

    Jean-Philippe Héberlé

    2009-10-01

    Full Text Available This article discusses Michael Berkeley’s opera Jane Eyre. Premiered on June 30, 2000 by Music Theatre Wales at the Cheltenham International Festival of Music, this opera is based on the novel by Charlotte Brontë and the libretto is written by the Australian poet, novelist, playwright and librettist, David Malouf. It was risky and daring to try to adapt this famous and long novel for the stage. We will particularly focus on the similarities and differences between the novel and the opera as well as on the strategies used both by David Malouf and Michael Berkeley to adapt it. Through the analysis of the similarities we will see how Michael Berkeley set to music some of the great themes and elements of the novel: passion, a sense of entrapment, the “Gothic” atmosphere. On the other hand, the analysis of the discrepancies between the novel and the opera as they appear in both the libretto and the music will lead us to a modern apprehension of the characterization of madness as well as of the metafictional dimension of the rewriting of Jane Eyre by David Malouf and Michael Berkeley.  

  18. Teoria feminista: o desafio de tornar-se um paradigma

    Directory of Open Access Journals (Sweden)

    Mirian Santos Paiva

    1997-12-01

    Full Text Available Partindo da crise do paradigma tradicional e tendo como epicentro a crítica feminista, este trabalho tenta mostrar o desafio que enfrenta a teoria feminista para tornar-se um novo paradigma e para tanto realiza-se uma pesquisa bibliográfica, consubstanciada na literatura pertinente ao tema. Evidencia-se que o desafio de ser um paradigma em ascensão faz com que esta teoria enfrente problemas teóricos, conceituais e metodológicos que precisam de um esforço conjunto para serem aprofundados e resolvidos. Todavia, o desenvolvimento desta teoria não depende apenas do mundo acadêmico, mas está também atrelado a mudanças na estrutura social, pois, de uma sociedade mais igualitária, mais facilmente emergirá um conhecimento sem dominação de gênero.

  19. Partitioning tungsten between matrix precursors and chondrule precursors through relative settling

    CERN Document Server

    Hubbard, Alexander

    2016-01-01

    Recent studies of chondrites have found a tungsten isotopic anomaly between chondrules and matrix. Given the refractory nature of tungsten, this implies that W was carried into the solar nebula by at least two distinct families of pre-solar grains. The observed chondrule/matrix split requires that the distinct families were kept separate during the dust coagulation process, and that the two families of grain interacted with the chondrule formation mechanism differently. We take the co-existence of different families of solids in the same general orbital region at the chondrule-precursor size as given, and explore the requirements for them to have interacted with the chondrule formation process at significantly different rates. We show that this sorting of families of solids into chondrule and matrix destined dust had to have been at least as powerful a sorting mechanism as the relative settling of aerodynamically distinct grains at at least two scale heights above the midplane. The requirement that the chondr...

  20. Partitioning Tungsten between Matrix Precursors and Chondrule Precursors through Relative Settling

    Science.gov (United States)

    Hubbard, Alexander

    2016-08-01

    Recent studies of chondrites have found a tungsten isotopic anomaly between chondrules and matrix. Given the refractory nature of tungsten, this implies that W was carried into the solar nebula by at least two distinct families of pre-solar grains. The observed chondrule/matrix split requires that the distinct families were kept separate during the dust coagulation process, and that the two families of grain interacted with the chondrule formation mechanism differently. We take the co-existence of different families of solids in the same general orbital region at the chondrule-precursor size as given, and explore the requirements for them to have interacted with the chondrule formation process at significantly different rates. We show that this sorting of families of solids into chondrule- and matrix-destined dust had to have been at least as powerful a sorting mechanism as the relative settling of aerodynamically distinct grains at least two scale heights above the midplane. The requirement that the chondrule formation mechanism was correlated in some fashion with a dust-grain sorting mechanism argues strongly for spatially localized chondrule formation mechanisms such as turbulent dissipation in non-thermally ionized disk surface layers, and argues against volume-filling mechanisms such as planetesimal bow shocks.

  1. Ultra-high resolution polarization-sensitive optical coherence microscopy for brain imaging at 6 um, 3.4 um and 1.3 um resolution (Conference Presentation)

    Science.gov (United States)

    Wang, Hui; Akkin, Taner; Magnain, Caroline V.; Yaseen, Mohammad A.; Cramer, Avilash; Wang, Ruopeng; Sakadžic, Sava; Boas, David A.

    2016-03-01

    Neuroanatomical pathways form the basis for functional activity of brain circuits. In the past, we developed a polarization-sensitive optical coherence tomography with serial scanning to achieve large-scale brain imaging. The system was able to visualize 3D fiber tracts of ~20 um in diameter. To investigate the neuroanatomical pathways at finer scales, we have now built a polarization-maintaining fiber based ultra-high resolution polarization-sensitive optical coherence microscope (PS-OCM) at 1300 nm. The PS-OCM has an axial resolution of 3.5 um in tissue. The detection setup consists of two spectrometers, acquiring spectral interference on orthogonal polarization channels. With a single measurement, the setup generates four contrasts: reflectivity, cross-polarization, retardance and optic axis orientation. To investigate the capability of PS-OCM at different resolutions, we used three microscope objectives that yield lateral resolutions of 6.0 um, 3.4 um and 1.3 um. Blocks of formalin fixed mouse brain and human brain were scanned. The cross-polarization and retardance images clearly depict the neuronal fiber structures, which are comparable with that generated by the maximum projection of volumetric reflectivity data. The optic axis orientation quantifies the in-plane fiber orientation. With the lateral resolution of 1.3 um, the retardance contrast is weak in white matter due to the shallow depth of focus. Overall, the ultra-high resolution PS-OCM provides a new tool to reveal neuroanatomical maps in the brain at cellular resolution.

  2. A vida singular de um jovem militante

    Directory of Open Access Journals (Sweden)

    Áurea Maria Guimarães

    2012-01-01

    Full Text Available Esse artigo é fruto de uma pesquisa realizada no período de 2007 a 2010, junto a jovens militantes da cidade de Campinas, com o objetivo de compreender as diferentes maneiras que conduziam esses jovens tanto a reproduzir um modelo de vida quanto a criar outras possibilidades de militância na relação com esse modelo. Entre as histórias orais de vida narradas por jovens que militavam em diferentes grupos ou instituições, escolhi a vida de Biula, representante do movimento estudantil secundarista, procurando evidenciar que a singularidade desta vida, como também e a de outros jovens, estava conectada à problematização que faziam no interior de certas práticas, histórica e culturalmente constituídas, possibilitando a criação de novas formas de subjetivação nas quais se modificava a experiência que tinham deles mesmos na relação com os seus heróis ou modelos de referência. Palavras-chave: história oral – transcriação – heróis – resistência - processos de singularização.   THE SINGULAR LIFE OF A YOUNG MILITANT ABSTRACT   This article is the result of a research carried out from 2007 to 2010 with   young militants in the city of Campinas, aiming to understand the different ways which conducted these youngsters to both reproduce a life model and create other possibilities of militancy in the relationship with this model. Among oral stories narrated by young militants from different groups or institutions, I have chosen the life of Biula, a representative of the secondary students’ movement, trying to show that the singularity of this life and other youngsters’ lives was connected to the problematization they promoted within certain practices, historically and culturally built, thus enabling the creation of new subjectification modes in which the experience they had of themselves in the relationship with their heroes or reference models has changed. Key words: oral history -  transcreation – heroes

  3. Neurodevelopment. Parasympathetic ganglia derive from Schwann cell precursors.

    Science.gov (United States)

    Espinosa-Medina, I; Outin, E; Picard, C A; Chettouh, Z; Dymecki, S; Consalez, G G; Coppola, E; Brunet, J-F

    2014-07-01

    Neural crest cells migrate extensively and give rise to most of the peripheral nervous system, including sympathetic, parasympathetic, enteric, and dorsal root ganglia. We studied how parasympathetic ganglia form close to visceral organs and what their precursors are. We find that many cranial nerve-associated crest cells coexpress the pan-autonomic determinant Paired-like homeodomain 2b (Phox2b) together with markers of Schwann cell precursors. Some give rise to Schwann cells after down-regulation of PHOX2b. Others form parasympathetic ganglia after being guided to the site of ganglion formation by the nerves that carry preganglionic fibers, a parsimonious way of wiring the pathway. Thus, cranial Schwann cell precursors are the source of parasympathetic neurons during normal development. PMID:24925912

  4. Experimental observation of precursor solitons in a flowing complex plasma

    Science.gov (United States)

    Jaiswal, Surabhi; Bandyopadhyay, P.; Sen, A.

    2016-04-01

    The excitation of precursor solitons ahead of a rapidly moving object in a fluid, a spectacular phenomenon in hydrodynamics that has often been observed ahead of moving ships, has surprisingly not been investigated in plasmas where the fluid model holds good for low frequency excitations such as ion acoustic waves. In this Rapid Communication we report an experimental observation of precursor solitons in a flowing dusty plasma. The nonlinear solitary dust acoustic waves (DAWs) are excited by a supersonic mass flow of the dust particles over an electrostatic potential hill. In a frame where the fluid is stationary and the hill is moving the solitons propagate in the upstream direction as precursors while wake structures consisting of linear DAWs are seen to propagate in the downstream region. A theoretical explanation of these excitations based on the forced Korteweg-deVries model equation is provided and their practical implications in situations involving a charged object moving in a plasma are discussed.

  5. Experimental observation of precursor solitons in a flowing complex plasma

    CERN Document Server

    Jaiswal, Surabhi; Sen, A

    2015-01-01

    The excitation of precursor solitons ahead of a rapidly moving object in a fluid, a spectacular phenomenon in hydrodynamics that has often been observed ahead of moving ships, has surprisingly not been investigated in plasmas where the fluid model holds good for low frequency excitations such as ion acoustic waves. In this paper we report the first experimental observation of precursor solitons in a flowing dusty plasma. The nonlinear solitary dust acoustic waves (DAWs) are excited by a supersonic mass flow of the dust particles over an electrostatic potential hill. In a frame where the fluid is stationary and the hill is moving the solitons propagate in the upstream direction as precursors while wake structures consisting of linear DAWs are seen to propagate in the downstream region. A theoretical explanation of these excitations based on the forced Korteweg-deVries model equation is provided and their practical implications in situations involving a charged object moving in a plasma are discussed.

  6. Precursors and electron-positron pair loading from erupting fireballs

    CERN Document Server

    Ramirez-Ruiz, E; Lazzati, D; Ramirez-Ruiz, Enrico; Fadyen, Andrew I. Mac; Lazzati, Davide

    2002-01-01

    Recent observations suggest that long-duration gamma-ray bursts and their afterglows are produced by highly relativistic jets emitted in core-collapse explosions. As the jet makes its way out of the stellar mantle, a bow shock runs ahead and a strong thermal precursor is produced as the shock breaks out. Such erupting fireballs produce a very bright gamma-ray precursor as they interact with the thermal break-out emission. The prompt gamma-ray emission propagates ahead of the fireball before it becomes optically thin, leading to electron-positron pair loading and radiative acceleration of the external medium. The detection of such precursors would offer the possibility of diagnosing not only the radius of the stellar progenitor and the initial Lorentz factor of the collimated fireball, but also the density of the external environment.

  7. L-arginine, a nitric oxide precursor, reduces dapsone-induced methemoglobinemia in rats

    Directory of Open Access Journals (Sweden)

    Natália Valadares de Moraes

    2012-03-01

    Full Text Available Dapsone use is frequently associated to hematological side effects such as methemoglobinemia and hemolytic anemia, which are related to N-hydroxylation mediated by the P450 enzyme system. The aim of the present study was to evaluate the influence of L-arginine supplementation, a precursor for the synthesis of nitric oxide, as single or multiple dose regimens on dapsone-induced methemoglobinemia. Male Wistar rats were treated with L-arginine at 5, 15, 30, 60 and 180 mg/kg doses (p.o., gavage in single or multiple dose regimens 2 hours prior to dapsone administration (40 mg/kg, i.p.. The effect of the nitric oxide synthase inhibitor L-NAME was investigated by treatment with multiple doses of 30 mg/kg (p.o., gavage 2 hours before dapsone administration. Blood samples were collected 2 hours after dapsone administration. Erythrocytic methemoglobin levels were assayed by spectrophotometry. The results showed that multiple dose supplementations with 5 and 15 mg/kg L-arginine reduced dapsone-induced methemoglobin levels. This effect is mediated by nitric oxide formation, since the reduction in methemoglobin levels by L-arginine is blocked by simultaneous administration with L-NAME, a nitric oxide synthase inhibitor.O uso da dapsona é frequentemente associado a efeitos adversos hematológicos, como a metemoglobinemia e anemia hemolítica, ambos relacionados com a N-hidroxilação mediada pelo sistema P450. O objetivo do estudo foi avaliar a influência da suplementação de L-arginina, um precursor da síntese de óxido nítrico, administrado em regime de dose única ou múltipla na metemoglobinemia induzida pela dapsona. Ratos machos Wistar foram tratados com L-arginina (po, gavagem em dose única ou múltipla de 5, 15, 30, 60 e 180 mg/kg 2 horas antes da administração de dapsona (40 mg/kg, ip. O efeito do L-NAME, um inibidor de óxido nítrico sintase (NOS, foi avaliado através do tratamento com doses múltiplas de 30 mg/kg. Amostras de sangue

  8. An advanced educational program for nuclear professionals with social scientific literacy. A collaborative initiative by UC Berkeley and Univ. of Tokyo on the Fukushima accident

    International Nuclear Information System (INIS)

    The authors have collaborated for over three years in developing an advanced educational program to cultivate leading engineers who can productively interact with other stakeholders. The program is organized under a partnership between the Nuclear Engineering Department of University of California, Berkeley (UCBNE) and the Global COE Program 'Nuclear Education and Research Initiative' (GoNERI) of the University of Tokyo, and is funded by MEXT (Ministry of Education, Culture, Sports, Science and Technology), Japan. We conducted two 'summer schools' in 2009 and 2010 as trial cases of the educational program. This year, in response to the Fukushima Daiichi nuclear accident, we decided to make our third summer school a venue for preliminary, yet multi-dimensional learning from that event. This school was held in Berkeley, CA, in the first week of August, with 12 lecturers and 18 students from various fields and countries. In this paper, we will explain the concept, aim, and design of our program; do a preliminary assessment of its effectiveness; introduce a couple of intriguing discussions held by participants; and discuss the program's implications for the post-Fukushima nuclear context. (author)

  9. The Behaviors of Optimal Precursors during Wintertime Eurasian Blocking Onset

    Institute of Scientific and Technical Information of China (English)

    JIANG Zhina; WANG Donghai

    2012-01-01

    In this paper the optimal precursors for wintertime Eurasian blocking onset are acquired by solving a nonlinear optimization problem whose objective function is constructed based on a blocking index with a triangular T21,three-level,quasi-geostrophic global spectral model.The winter climatological state is chosen as the reference basic state.Numerical results show that the optimal precursors are characterized by a baroclinic pattern with a westward tilt with height,which are mainly located upstream of the blocking region.For an optimization time of 5 days,these perturbations are mainly localized over the Northeast Atlantic Ocean and continental Europe. With the extension of the optimization time to 8 days,these perturbations are distributed more upstream and extensively in the zonal direction.Wave spectrum analysis reveals that the optimal precursors are composed of not only synoptic-scale (wave numbers 5 18) waves,but planetary-scale (wave numbers 0-4) waves as well.The synoptic-scale optimal precursors are mainly located in the mid-latitude area,while the planetary-scale optimal precursors focus primarily on the highlatitude region.The formation of a strong planetary-scale positive blocking anomaly is accompanied by the reinforcement of synoptic-scale perturbations and further fragmentation into two branches,in which the northern branch is generally stronger than the southern one.The eddy forcing arising from the selfinteraction of synoptic-scale disturbances is shown to be crucial in triggering the dipole blocking anomaly,and the planetary-scale optimal precursor provides the initial favorable background conditions for blocking onset.

  10. Um modelo para analisar o problema de filas em caixas de supermercados: um estudo de caso

    Directory of Open Access Journals (Sweden)

    Reinaldo Morabito

    2000-06-01

    Full Text Available Neste estudo aplicamos teoria de filas para analisar o problema de congestão em caixas de supermercados. Estamos particularmente interessados em modelar o tempo médio de espera em fila, aqui entendido como uma componente importante do nível de serviço ao consumidor, em função da capacidade do sistema (i.e., o número de caixas num dado período de tempo. Três modelos são explorados: (i representar o sistema por meio de um simples modelo M/M/m de fila única, onde m é o número de caixas, (ii representar o sistema por meio de m modelos M/M/1 paralelos e independentes, e (iii representar o sistema por meio de um modelo Markoviano mais geral, onde os dois modelos anteriores podem ser vistos como casos particulares. Para avaliar o desempenho destes modelos, realizamos um estudo de caso num dos supermercados da rede Jaú-Serve, localizado no interior de São Paulo. Os resultados mostraram que o terceiro modelo pode resultar numa boa aproximação para o problema, ao contrário dos dois primeiros.In this study we applied queueing theory to analyze the problem of congestion in supermarket check-outs. We are particularly concerned with modeling the mean user waiting time in the queue, viewed as an important component of the user service, as a function of the capacity of the system (i.e., the number of cashiers in a given time period. Three models are explored: (i to represent the system by means of a simple M/M/m queueing model, where m is the number of cashiers, (ii to represent the system by means of m parallel and independent M/M/1 queueing models, and (iii to represent the system by means of a more generic Markovian model, where the former models can be viewed as particular cases. In order to evaluate the performance of the models, we developed a case study in one of the supermarkets of Jaú-Serve chain located in São Paulo State. The results showed that the third model can yield a good approximation for the problem, different from the

  11. Do glycine-extended hormone precursors have clinical significance?

    DEFF Research Database (Denmark)

    Rehfeld, Jens Frederik

    2014-01-01

    Half of the known peptide hormones are C-terminally amidated. Subsequent biogenesis studies have shown that the immediate precursor is a glycine-extended peptide. The clinical interest in glycine-extended hormones began in 1994, when it was suggested that glycine-extended gastrin stimulated cancer...... and clinical effects of glycine-extended precursors for most other amidated hormones than gastrin and cholecystokinin (CCK). The idea of glycine-extended peptides as independent messengers was interesting. But clinical science has to move ahead from ideas that cannot be supported at key points after decades...

  12. Differentiation of Mouse Embryonic Stem Cells into Ventral Foregut Precursors

    DEFF Research Database (Denmark)

    Rothová, Michaela; Hölzenspies, Jurriaan J; Livigni, Alessandra;

    2016-01-01

    Anterior definitive endoderm (ADE), the ventral foregut precursor, is both an important embryonic signaling center and a unique multipotent precursor of liver, pancreas, and other organs. Here, a method is described for the differentiation of mouse embryonic stem cells (mESCs) to definitive...... endoderm with pronounced anterior character. ADE-containing cultures can be produced in vitro by suspension (embryoid body) culture or in a serum-free adherent monolayer culture. ESC-derived ADE cells are committed to endodermal fates and can undergo further differentiation in vitro towards ventral foregut...

  13. Synthesis of GAP and PAMMO Homopolymers from Mesylate Polymeric Precursors

    Science.gov (United States)

    Mura, Claudio; Fruci, Stefania; Lamia, Pietro; Cappello, Miriam; Filippi, Sara; Polacco, Giovanni

    2016-04-01

    In azidic binders for solid propellants, the N3 functionality is introduced by substitution of a halogen or tosyl group, but recently the mesyl group has been suggested as an alternative. The mesylate group has two advantages, mainly related to its small dimensions and low cost. Poly(glycidyl azide) and poly 3-azidomethyl-3-methyl oxetane were prepared by using both tosylate and mesylate precursors. The azidation kinetics were studied at three different temperatures while keeping all other operating parameters the same. The results confirmed the good potential of the mesylate precursors for the production of azidic binders.

  14. 3-D rheologic model of earthquake preparation (Ⅲ): Precursor field

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    On the basis of the theory of viscoelastic displacement and strain field for the three-dimensional rheologic model of earthquake preparation, this paper mainly studies the theoretical solution of precursor field for the three-dimensional rheologic model of earthquake preparation. We derive the viscoelastic analytical expressions of the ground tilt, underground water level, earth resistivity at an arbitrary point (x, y, z) in the rheologic medium, and analyzed the earth resistivity preliminarily, providing a certain theoretical basis for the precursor analysis of seismogenic process.

  15. "Um por todos, todos pela música nova" : um estudo de caso

    OpenAIRE

    Milheiro, Maria Helena Cruz Martins Rodrigues

    2013-01-01

    Este trabalho explora o processo de ensino de música nas bandas filarmónicas em Portugal, através de métodos qualitativos e quantitativos. Parte de um estudo de caso realizado na Banda dos Bombeiros Voluntários de Ílhavo – Música Nova, inserindo-se no âmbito do projeto MIMAR, em curso no Instituto de Etnomusicologia – Centro de Estudos em Música e Dança, na Universidade de Aveiro. As Bandas Filarmónicas são instituições seculares responsáveis pela formação inicial de grande parte dos instr...

  16. The Presence of Modifiable Residues in the Core Peptide Part of Precursor Nisin Is Not Crucial for Precursor Nisin Interactions with NisB- and NisC

    NARCIS (Netherlands)

    Khusainov, Rustem; Kuipers, Oscar P.; Hofmann, Andreas

    2013-01-01

    Precursor nisin is a model posttranslationally modified precursor lantibiotic that can be structurally divided into a leader peptide sequence and a modifiable core peptide part. The nisin core peptide clearly plays an important role in the precursor nisin - nisin modification enzymes interactions, s

  17. Anemia hemolítica imunomediada não regenerativa em um cão

    OpenAIRE

    Brandão Leonardo Pinto; Ikesaki Júlia Habu; Miyashiro Samantha Ive; Franchini Maria Luisa; Hagiwara Mitika Kuribayashi

    2004-01-01

    Quadros hemolíticos não eritrorregenerativos são descritos em cães e podem ser decorrentes de doença medular primária, bem como, da destruição dos precursores eritróides medulares por imunoglobulinas. Um cão macho, de três anos de idade, sem raça definida, foi atendido no Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo apresentando sinais de anemia hemolítica aguda arregenerativa. Após a instituição de terapia imunossupressora (prednisona), h...

  18. Technical Note: Methionine, a precursor of methane in living plants

    Science.gov (United States)

    Lenhart, K.; Althoff, F.; Greule, M.; Keppler, F.

    2015-03-01

    When terrestrial plants were identified as producers of the greenhouse gas methane, much discussion and debate ensued not only about their contribution to the global methane budget but also with regard to the validity of the observation itself. Although the phenomenon has now become more accepted for both living and dead plants, the mechanism of methane formation in living plants remains to be elucidated and its precursor compounds to be identified. We made use of stable isotope techniques to verify the in vivo formation of methane, and, in order to identify the carbon precursor, 13C positionally labeled organic compounds were employed. Here we show that the amino acid L-methionine acts as a methane precursor in living plants. Employing 13C-labeled methionine clearly identified the sulfur-bound methyl group of methionine as a carbon precursor of methane released from lavender (Lavandula angustifolia). Furthermore, when lavender plants were stressed physically, methane release rates and the stable carbon isotope values of the emitted methane greatly increased. Our results provide additional support that plants possess a mechanism for methane production and suggest that methionine might play an important role in the formation of methane in living plants, particularly under stress conditions.

  19. Technical note: Methionine, a precursor of methane in living plants

    Directory of Open Access Journals (Sweden)

    K. Lenhart

    2014-11-01

    Full Text Available When terrestrial plants were identified as producers of the greenhouse gas methane, much discussion and debate ensued, not only about their contribution to the global methane budget, but also with regard to the validity of the observation itself. Although the phenomenon has now become more accepted for both living and dead plants, the mechanism of methane formation in living plants remains to be elucidated and its precursor compounds identified. We made use of stable isotope techniques to verify in vivo formation of methane and, in order to identify the carbon precursor, 13C-positionally labelled organic compounds were employed. Here we show that the amino acid L-methionine acts as a methane precursor in living plants. Employing 13C-labelled methionine clearly identified the sulphur-bound methyl group of methionine as a carbon precursor of methane released from lavender (Lavandula angustifolia. Furthermore, when lavender plants were stressed physically, methane release rates and the stable carbon isotope values of the emitted methane greatly increased. Our results provide additional support that plants possess a mechanism for methane production and suggest that methionine might play an important role in the formation of methane in living plants, particularly under stress conditions.

  20. Multiple Modes of Communication between Neurons and Oligodendrocyte Precursor Cells

    NARCIS (Netherlands)

    Maldonado, Paloma P; Angulo, María Cecilia

    2015-01-01

    The surprising discovery of bona fide synapses between neurons and oligodendrocytes precursor cells (OPCs) 15 years ago placed these progenitors as real partners of neurons in the CNS. The role of these synapses has not been established yet, but a main hypothesis is that neuron-OPC synaptic activity

  1. NASA's Accident Precursor Analysis Process and the International Space Station

    Science.gov (United States)

    Groen, Frank; Lutomski, Michael

    2010-01-01

    This viewgraph presentation reviews the implementation of Accident Precursor Analysis (APA), as well as the evaluation of In-Flight Investigations (IFI) and Problem Reporting and Corrective Action (PRACA) data for the identification of unrecognized accident potentials on the International Space Station.

  2. Glutamine: precursor or nitrogen donor for citrulline synthesis?

    Science.gov (United States)

    Glutamine (Gln) is considered the main precursor for citrulline (Cit) synthesis, but no attempts have been made to differentiate the contribution of Gln carbon (Gln-C) skeleton vs. the nonspecific contribution through NH3 and CO2. To study the contribution of dietary Gln-N to the synthesis of Cit, t...

  3. Reverse Detection of Short-Term Earthquake Precursors

    CERN Document Server

    Keilis-Borok, V; Gabrielov, A; Turcotte, D L

    2003-01-01

    We introduce a new approach to short-term earthquake prediction based on the concept of selforganization of seismically active fault networks. That approach is named "Reverse Detection of Precursors" (RDP), since it considers precursors in reverse order of their appearance. This makes it possible to detect precursors undetectable by direct analysis. Possible mechanisms underlying RDP are outlined. RDP is described with a concrete example: we consider as short-term precursors the newly introduced chains of earthquakes reflecting the rise of an earthquake correlation range; and detect (retrospectively) such chains a few months before two prominent Californian earthquakes - Landers, 1992, M = 7.6, and Hector Mine, 1999, M = 7.3, with one false alarm. Similar results (described elsewhere) are obtained by RDP for 21 more strong earthquakes in California (M >= 6.4), Japan (M >= 7.0) and the Eastern Mediterranean (M >= 6.5). Validation of the RDP approach requires, as always, prediction in advance for which this stu...

  4. Proteomic analysis of osteogenic differentiation of dental follicle precursor cells

    DEFF Research Database (Denmark)

    Morsczeck, Christian; Petersen, Jørgen; Völlner, Florian;

    2009-01-01

    of differentiation. In the present study we applied 2-DE combined with capillary-LC-MS/MS analysis to profile differentially regulated proteins upon differentiation of dental follicle precursor cells (DFPCs). Out of 115 differentially regulated proteins, glutamine synthetase, lysosomal proteinase cathepsin B...

  5. The miR-10 microRNA precursor family

    DEFF Research Database (Denmark)

    Tehler, Disa; Høyland-Kroghsbo, Nina Molin; Lund, Anders H

    2011-01-01

    The miR-10 microRNA precursor family encodes a group of short non-coding RNAs involved in gene regulation. The miR-10 family is highly conserved and has sparked the interest of many research groups because of the genomic localization in the vicinity of, coexpression with and regulation of the Hox...

  6. College Student Stress: A Predictor of Eating Disorder Precursor Behaviors

    Science.gov (United States)

    Shelton, Virginia L.; Valkyrie, Karena T.

    2010-01-01

    Eating disorders are compulsive behaviors that can consume a person's life to the point of becoming life threatening. Previous research found stress associated with eating disorders. College can be a stressful time. If stress predicted precursor behaviors to eating disorders, then counselors would have a better chance to help students sooner. This…

  7. Developmental Dyslexia: Early Precursors, Neurobehavioral Markers, and Biological Substrates

    Science.gov (United States)

    Benasich, April A., Ed.; Fitch, R. Holly, Ed.

    2012-01-01

    Understanding the precursors and early indicators of dyslexia is key to early identification and effective intervention. Now there's a single research volume that brings together the very latest knowledge on the earliest stages of dyslexia and the diverse genetic, neurobiological, and cognitive factors that may contribute to it. Based on findings…

  8. Transmembrane transport of peptidoglycan precursors across model and bacterial membranes

    NARCIS (Netherlands)

    van Dam, V.; Sijbrandi, R.; Kol, M.A.; Swiezewska, E.; de Kruijff, B.; Breukink, E.J.

    2007-01-01

    Translocation of the peptidoglycan precursor Lipid II across the cytoplasmic membrane is a key step in bacterial cell wall synthesis, but hardly understood. Using NBD-labelled Lipid II, we showed by fluorescence and TLC assays that Lipid II transport does not occur spontaneously and is not induced b

  9. Synthesis of new diverse macrocycles from diol precursors

    DEFF Research Database (Denmark)

    Madsen, Charlotte Marie; Hansen, Martin; Thrane, Marie V.;

    2010-01-01

    The formation of a library of diverse macrocycles with different ring sizes from two easily accessible building blocks is presented. Reacting diol precursors with electrophilic reagents lead to 17-membered sulfites and 19-membered malonates in 34–79% yield. Double-reductive amination of dialdehyd...

  10. Manganite perovskite ceramics, their precursors and methods for forming

    Energy Technology Data Exchange (ETDEWEB)

    Payne, David Alan; Clothier, Brent Allen

    2015-03-10

    Disclosed are a variety of ceramics having the formula Ln.sub.1-xM.sub.xMnO.sub.3, where 0.Itoreq.x.Itoreq.1 and where Ln is La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu or Y; M is Ca, Sr, Ba, Cd, or Pb; manganite precursors for preparing the ceramics; a method for preparing the precursors; and a method for transforming the precursors into uniform, defect-free ceramics having magnetoresistance properties. The manganite precursors contain a sol and are derived from the metal alkoxides: Ln(OR).sub.3, M(OR).sub.2 and Mn(OR).sub.2, where R is C.sub.2 to C.sub.6 alkyl or C.sub.3 to C.sub.9 alkoxyalkyl, or C.sub.6 to C.sub.9 aryl. The preferred ceramics are films prepared by a spin coating method and are particularly suited for incorporation into a device such as an integrated circuit device.

  11. Observation of laser driven supercritical radiative shock precursors.

    Science.gov (United States)

    Bouquet, S; Stéhlé, C; Koenig, M; Chièze, J-P; Benuzzi-Mounaix, A; Batani, D; Leygnac, S; Fleury, X; Merdji, H; Michaut, C; Thais, F; Grandjouan, N; Hall, T; Henry, E; Malka, V; Lafon, J-P J

    2004-06-01

    We present a supercritical radiative shock experiment performed with the LULI nanosecond laser facility. Using targets filled with xenon gas at low pressure, the propagation of a strong shock with a radiative precursor is evidenced. The main measured shock quantities (electronic density and propagation velocity) are shown to be in good agreement with theory and numerical simulations. PMID:15245230

  12. The isoprenoid-precursor dependence of Plasmodium spp

    NARCIS (Netherlands)

    van der Meer, Jan-Ytzen; Hirsch, Anna K. H.

    2012-01-01

    Due to the increase in resistance of Plasmodium spp. against available antimalarials, there is a need for new, effective and innovative drugs. The non-mevalonate pathway for the biosynthesis of the universal isoprenoid precursors, which is absent in humans, is suggested as an attractive source of ta

  13. Regression analysis of reported earthquake precursors. I. Presentation of data

    Science.gov (United States)

    Niazi, Mansour

    1984-11-01

    Around 700 reported precursors of about 350 earthquakes, including the negative observations, have been compiled in 11 categories with 31 subdivisions. The data base is subjected to an initial sorting and screening by imposing three restrictions on the ranges of main shock magnitude ( M≥4.0), precursory time ( t≤20 years), and the epicentral distance of observation points ( X m≤4.100.3 M ). Of the 31 subcategories of precursory phenomena, 18 with 9 data points or more are independently studied by regressing their precursory times against magnitude. The preliminary results tend to classify the precursors into three groups: 1. The precursors which show weak or no correlation between time and the magnitude of the eventual main shock. Examples of this group are foreshocks and precursory tilt. 2. The precursors which show clear scaling with magnitude. These include seismic velocity ratio ( V p/Vs), travel time delay, duration of seismic quiescence, and, to some degree, the variation of b-value, and anomalous seismicity. 3. The precursors which display clustering of precursory times around a mean value, which differs for different precursors from a few hours to a few years. Examples include the conductivity rate, geoelectric current and potential, strain, water well level, geochemical anomalies, change of focal mechanism, and the enhancement of seismicity reported only for larger earthquakes. Some of the precursors in this category, such as leveling changes and the occurrence of microseismicity, show bimodal patterns of precursory times and may partially be coseismic. In addition, each category with a sufficient number of reported estimates of distance and signal amplitude is subjected to multiple linear regression. The usefulness of these regressions at this stage appears to be limited to specifying which of the parameters shows a more significant correlation. Standard deviations of residuals of precursory time against magnitude are generally reduced when

  14. Medidas da umidade relativa do ar em um ambiente fechado

    Directory of Open Access Journals (Sweden)

    Costa Eden V.

    2003-01-01

    Full Text Available Umidade do ar e o vapor d'água presente na atmosfera. Neste trabalho medimos a umidade relativa do ar em um ambiente fechado onde a temperatura foi mantida constante. Nestas condições, a umidade cresce até o vapor d'água tornar-se saturado. Neste instante, a umidade é máxima. O aparato experimental utilizado consiste de recipiente fechado de vidro, higrômetro, termômetro e relógio. Trata-se, portanto, de um experimento simples, possível de ser realizado em um laboratório didático e capaz de preencher a lacuna dos livros de texto de física, que, em geral, negligenciam este tópico.

  15. Sobre a Pesquisa nas Artes: um discurso amoroso

    Directory of Open Access Journals (Sweden)

    Victoria Pérez Royo

    2015-09-01

    Full Text Available Este artigo resulta de um exercício de reescrita experimental e de um pensamento analógico cujo objetivo era abrir uma nova perspectiva sobre pesquisa nas artes. Metodologicamente, as diferentes figuras de amor no livro Fragmentos de um Discurso Amoroso, de Barthes, são levadas a conversar sobre a relação entre pesquisador e objeto de estudo. Essa analogia nos permite encontrar parâmetros de qualidade baseados em uma escala de valores diferentes dos hegemônicos na academia (produtividade, competitividade, inovação. Esses novos parâmetros podem constituir uma sólida base ontológica para a construção de uma nova política de pesquisa artística na academia que permita uma reconsideração radical dos processos de investigação em artes.

  16. Mechanical design and fabrication of the VHF-gun, the Berkeley normal-conducting continuous-wave high-brightness electron source

    Science.gov (United States)

    Wells, R. P.; Ghiorso, W.; Staples, J.; Huang, T. M.; Sannibale, F.; Kramasz, T. D.

    2016-02-01

    A high repetition rate, MHz-class, high-brightness electron source is a key element in future high-repetition-rate x-ray free electron laser-based light sources. The VHF-gun, a novel low frequency radio-frequency gun, is the Lawrence Berkeley National Laboratory (LBNL) response to that need. The gun design is based on a normal conducting, single cell cavity resonating at 186 MHz in the VHF band and capable of continuous wave operation while still delivering the high accelerating fields at the cathode required for the high brightness performance. The VHF-gun was fabricated and successfully commissioned in the framework of the Advanced Photo-injector EXperiment, an injector built at LBNL to demonstrate the capability of the gun to deliver the required beam quality. The basis for the selection of the VHF-gun technology, novel design features, and fabrication techniques are described.

  17. Physics on your feet Berkeley graduate exam questions : or ninety minutes of shame but a PhD for the rest of your life!

    CERN Document Server

    Budker, Dmitry; Demas, Vasiliki

    2015-01-01

    Physics on Your Feet gives a collection of physics problems covering the broad range of topics in classical and modern physics that were, or could have been, asked at oral PhD exams at Berkeley. The questions are easy to formulate, but some of them can only be answered using an out-of-the-box approach. Detailed solutions are provided, from which the reader is guaranteed to learn a lot about the physicists' way of thinking. The book is also packed full of cartoons and dry humour to help take the edge off the stress and anxiety surrounding exams. This is a helpful guide to students preparing for their exams, as well as to University lecturers looking for good instructive problems. No exams are necessary to enjoy the book!

  18. O vampiro, um não morto ainda vivo

    Directory of Open Access Journals (Sweden)

    Max Kohn

    2012-12-01

    Full Text Available O que um vampiro representa? Por que ocupa tal lugar na cultura? O vampiro é um invariante cultural com diferenças culturais. O vivente é um não morto (undead, e o não morto ainda está vivo. Do ponto de vista psicanalítico, qual é, então, essa relação com os dentes e com a mordida que contamina, que faz com que o outro se torne também um vampiro? O vampiro é um bebê que morde e tem um desejo ambivalente de imortalidade. O leite materno é vital como o é o sangue para o vampiro. A brincadeira de mordiscar, para o bebê winnicottiano, conta mais do que a mordida para o bebê kleiniano. O bebê kleiniano é mais próximo do vampiro do que o bebê winnicottiano.The Vampire, a live undead. What does a vampire represent? Why does he have such a place in the culture? It is a cultural invariant with cultural differences. The living is an undead and the undead is still living. From a psychoanalytical point of view, what is the connection to teeth and to bites that contaminate, and make the other become a vampire? The vampire is a baby that bites and who has an ambivalent desire of immortality. Maternal milk is as vital as blood for the vampire. The game of biting for the Winnicottian baby is more important than the bite for the Kleinian baby. The Kleinian baby is closer to the vampire than the winnicotian baby.

  19. Whole-cell fungal transformation of precursors into dyes

    Directory of Open Access Journals (Sweden)

    Jarosz-Wilkołazka Anna

    2010-07-01

    Full Text Available Abstract Background Chemical methods of producing dyes involve extreme temperatures and unsafe toxic compounds. Application of oxidizing enzymes obtained from fungal species, for example laccase, is an alternative to chemical synthesis of dyes. Laccase can be replaced by fungal biomass acting as a whole-cell biocatalyst with properties comparable to the isolated form of the enzyme. The application of the whole-cell system simplifies the transformation process and reduces the time required for its completion. In the present work, four fungal strains with a well-known ability to produce laccase were tested for oxidation of 17 phenolic and non-phenolic precursors into stable and non-toxic dyes. Results An agar-plate screening test of the organic precursors was carried out using four fungal strains: Trametes versicolor, Fomes fomentarius, Abortiporus biennis, and Cerrena unicolor. Out of 17 precursors, nine were transformed into coloured substances in the presence of actively growing fungal mycelium. The immobilized fungal biomass catalyzed the transformation of 1 mM benzene and naphthalene derivatives in liquid cultures yielding stable and non-toxic products with good dyeing properties. The type of fungal strain had a large influence on the absorbance of the coloured products obtained after 48-hour transformation of the selected precursors, and the most effective was Fomes fomentarius (FF25. Whole-cell transformation of AHBS (3-amino-4-hydroxybenzenesulfonic acid into a phenoxazinone dye was carried out in four different systems: in aqueous media comprising low amounts of carbon and nitrogen source, in buffer, and in distilled water. Conclusions This study demonstrated the ability of four fungal strains belonging to the ecological type of white rot fungi to transform precursors into dyes. This paper highlights the potential of fungal biomass for replacing isolated enzymes as a cheaper industrial-grade biocatalyst for the synthesis of dyes and other

  20. Um hino entre Tebas e Atenas: um exemplo da polifonia coral em Antígona

    Directory of Open Access Journals (Sweden)

    Agatha Bacelar

    2014-09-01

    Full Text Available Na Atenas clássica, a tragédia integrava uma tradição mais vasta, a da poesia coral. Um dos traços mais característicos dessa tradição poética é sua vinculação à ocasião de execução, observada, por exemplo, no uso recorrente de dêiticos com referência à situação em questão. Os coros trágicos, no entanto, cantam e dançam em uma situação ficcional durante um festival em honra a Dioniso. Como resultado, os dêiticos empregados nas partes líricas das tragédias podem assumir referentes ambíguos, projetando a situação cultual dos coreutas sobre a situação ficcional dos personagens que interpretam. Este trabalho pretende analisar essas projeções no quinto estásimo da Antígona de Sófocles.Abstract: In Classical Athens, tragedy took part in the larger tradition of choral poetry. One of the most characteristic features of this poetic tradition is its attachment to the occasion of performance, observed for example by the recurrent use of deictic words that refers to the situation in question. The tragic choruses, however, sing and dance in a fictional situation during a festival in honor of Dionysus. As a result, the deictics employed in tragic lyrics may assume ambiguous referents, projecting the cultic situation of the choreutes into the fictional situation of the characters they play. This paper intends to analyze these projections in the fifth stasimon of Sophocles’ Antigone.Keywords: Greek choral poetry; Attic tragedy; Sophocles’ Antigone; Dionysus’ cultsAgatha Bacelar é bacharel em Letras Português-Grego pela Universidade Federal do Rio de Janeiro e Mestre em Letras Clássicas pela mesma instituição, título obtido com a dissertação A Liminaridade trágica em Ájax, de Sófocles, sob orientação de Nely Maria Pessanha. Como doutoranda em ‘Histoire et civilizations’ na École des Hautes Études en Sciences Sociales, é membro da equipe “ANHIMA” (Anthropologie et Histoire des Mondes Anciens

  1. QuorUM: An Error Corrector for Illumina Reads.

    Directory of Open Access Journals (Sweden)

    Guillaume Marçais

    Full Text Available Illumina Sequencing data can provide high coverage of a genome by relatively short (most often 100 bp to 150 bp reads at a low cost. Even with low (advertised 1% error rate, 100 × coverage Illumina data on average has an error in some read at every base in the genome. These errors make handling the data more complicated because they result in a large number of low-count erroneous k-mers in the reads. However, there is enough information in the reads to correct most of the sequencing errors, thus making subsequent use of the data (e.g. for mapping or assembly easier. Here we use the term "error correction" to denote the reduction in errors due to both changes in individual bases and trimming of unusable sequence. We developed an error correction software called QuorUM. QuorUM is mainly aimed at error correcting Illumina reads for subsequent assembly. It is designed around the novel idea of minimizing the number of distinct erroneous k-mers in the output reads and preserving the most true k-mers, and we introduce a composite statistic π that measures how successful we are at achieving this dual goal. We evaluate the performance of QuorUM by correcting actual Illumina reads from genomes for which a reference assembly is available.We produce trimmed and error-corrected reads that result in assemblies with longer contigs and fewer errors. We compared QuorUM against several published error correctors and found that it is the best performer in most metrics we use. QuorUM is efficiently implemented making use of current multi-core computing architectures and it is suitable for large data sets (1 billion bases checked and corrected per day per core. We also demonstrate that a third-party assembler (SOAPdenovo benefits significantly from using QuorUM error-corrected reads. QuorUM error corrected reads result in a factor of 1.1 to 4 improvement in N50 contig size compared to using the original reads with SOAPdenovo for the data sets investigated.QuorUM

  2. Cinema em cartazes: um passeio pelo percurso da escrita verbovisual

    Directory of Open Access Journals (Sweden)

    Denise Azevedo Duarte Guimarães

    2011-01-01

    Full Text Available Este artigo tem cartazes de cinema como objeto de estudo e pretende demonstrar como eles dão continuidade, hoje, a um projeto em busca da visualidade, proveniente do barroco e que conquista espaço e forma na contemporaneidade. A linguagem do cartaz, como produto comunicativo híbrido, é analisada por intermédio de um estudo comparativo sobre a evolução da poesia visual no ocidente. Uma leitura intersemiótica tenta investigar processos criativos que integram signos verbais e interfaces icônicas no texto impresso.

  3. Gravidez na adolescência: um olhar sobre um fenômeno complexo

    Directory of Open Access Journals (Sweden)

    Ana Cristina Garcia Dias

    2010-04-01

    Full Text Available O presente trabalho apresenta uma revisão seletiva e não sistemática da literatura a respeito do fenômeno da gestação na adolescência. Três eixos temáticos orientam a organização do trabalho: (a Riscos e problemas associados à gestação na adolescência; (b Fatores precursores relacionados à gravidez na adolescência; e (c Fatores sócio-culturais associados ao desejo de ser mãe na adolescência. Entre as conclusões, destaca-se que a gravidez na adolescência é uma experiência que pode ter consequências tanto negativas quanto positivas para os adolescentes. Além disso, o fenômeno evidencia a necessidade de intervenções voltadas à saúde sexual e reprodutiva dos adolescentes.

  4. Enzyme-triggered and self-cleaving fragrant alcohol precursors.

    Science.gov (United States)

    Flachsmann, Felix; Gautschi, Markus; Bachmann, Jean-Pierre; Brunner, Gerhard

    2008-06-01

    The high volatility and water solubility of many natural perfumery alcohols leads to their rapid loss in fabric-care and personal-care applications. A dramatically enhanced substantivity is achieved by the use of fragrance precursors as controlled-release systems. In the first part of this article, we present multi-odorant precursors, in which the enzymatic cleavage of esters or carbonates of fragrant alcohols triggers subsequent steps leading to the release of fragrant ketones, lactones, and additional fragrant alcohols. In the second part, a study on oligocarbonates of fragrant alcohols is presented. Therein, the outstanding enzyme-independent performance of gluconolactone oligocarbonate 27 for the long-lasting release of (Z)-hex-3-en-1-ol is highlighted. We show that these polyfunctional compounds undergo complex rearrangements and intramolecular substitution reactions which lead to the observed release kinetics. PMID:18618399

  5. Precursors for liver gluconeogenesis in periparturient dairy cows

    DEFF Research Database (Denmark)

    Larsen, Mogens; Kristensen, Niels Bastian

    2013-01-01

    lactation, presumably accounting for the observed lack of glucogenic precursors to balance estimated glucose need. Until recently, there has been paucity in quantitative data on liver nutrient metabolism in the periparturient period. Propionate is the quantitatively most important glucogenic precursor...... throughout the periparturient period. However, the immediate post partum increment in liver release of glucose is not followed by an equivalent increment in propionate uptake, because of the lower rate of increment in feed intake compared with the rate of increment in requirements for milk synthesis....... The quantitative data on liver metabolism of AA do not support the hypothesis that the rapid post partum increase in net liver release of glucose is supported by increased utilisation of AA for gluconeogenesis. Only alanine is likely to contribute to liver release of glucose through its role in the inter...

  6. Precursors and metabolic pathway for guaiacol production by Alicyclobacillus acidoterrestris.

    Science.gov (United States)

    Cai, Rui; Yuan, Yahong; Wang, Zhouli; Guo, Chunfeng; Liu, Bin; Liu, Laping; Wang, Yutang; Yue, Tianli

    2015-12-01

    Alicyclobacillus acidoterrestris has recently received much attention due to its implication in the spoilage of pasteurized fruit juices, which was manifested by the production of guaiacol. Vanillic acid and vanillin have been accepted as the biochemical precursors of guaiacol in fruit juices. The purpose of this study was to try to find other precursors and elucidate details about the conversion of vanillic acid and vanillin to guaiacol by A. acidoterrestris. Four potential substrates including ferulic acid, catechol, phenylalanine and tyrosine were analyzed, but they could not be metabolized to guaiacol by all the thirty A. acidoterrestris strains tested. Resting cell studies and enzyme assays demonstrated that vanillin was reduced to vanillyl alcohol by NADPH-dependent vanillin reductase and oxidized to vanillic acid by NAD(P)(+)-dependent vanillin dehydrogenases in A. acidoterrestris DSM 3923. Vanillic acid underwent a nonoxidative decarboxylation to guaiacol. The reversible vanillic acid decarboxylase involved was oxygen insensitive and pyridine nucleotide-independent. PMID:26241489

  7. Whistler damping at oblique propagation - Laminar shock precursors

    Science.gov (United States)

    Gary, S. P.; Mellott, M. M.

    1985-01-01

    This paper addresses the collisionless damping of whistlers observed as precursors standing upstream of oblique, low-Mach number terrestrial bow shocks. The linear theory of electromagnetic waves in a homogeneous Vlasov plasma with Maxwellian distribution functions and a magnetic field is considered. Numerical solutions of the full dispersion equation are presented for whistlers propagating at an arbitrary angle with respect to the magnetic field. It is demonstrated that electron Landau damping attenuates oblique whistlers and that the parameter which determines this damping is beta-e. In a well-defined range of parameters, this theory provides damping lengths which are the same order of magnitude as those observed. Thus electron Landau damping is a plausible process in the dissipation of upstream whistlers. Nonlinear plasma processes which may contribute to precursor damping are also discussed, and criteria for distinguishing among these are described.

  8. Study of the Optimal Precursors for Blocking Events

    Institute of Scientific and Technical Information of China (English)

    JIANG Zhina; LUO Dehai

    2005-01-01

    The precursors of dipole blocking are obtained by a numerical approach based upon a quasi-geostrophic barotropic planetary- to synoptic-scale interaction model without topography and with a localized synopticscale wave-maker. The optimization problem related to the precursors of blocking is formulated and the nonlinear optimization method is used to examine the optimal synoptic-scale initial field successfully. The results show that the prominent characteristics of the optimal synoptic-scale initial field are that the synoptic-scale wave train structures exist upstream of the incipient blocking. In addition, the large-scale low/high eddy-forcing pattern upstream of the incipient blocking is an essential precondition for the onset of dipole blocking.

  9. Turbulence-induced magnetic fields in shock precursors

    CERN Document Server

    del Valle, Maria Victoria; Santos-Lima, Reinaldo

    2016-01-01

    Galactic cosmic rays are believed to be mostly accelerated at supernova shocks. However, the interstellar magnetic field is too weak to efficiently accelerate galactic cosmic rays up to the highest energies, i.e. $10^{15}$ eV. A stronger magnetic field in the pre-shock region could provide the efficiency required. Bell's cosmic-ray nonresonant streaming instability has been claimed to be responsible for the amplification of precursor magnetic fields. However, an alternative mechanism has been proposed in which the cosmic-ray pressure gradient forms the shock precursor and drives turbulence, amplifying the magnetic field via the small-scale dynamo. A key ingredient for the mechanism to operate are the inhomogeneities present in the interstellar medium (ISM). These inhomogeneities are the consequence of turbulence. In this work we explore the magnetic field amplification in different ISM conditions through 3D MHD numerical simulations.

  10. Experimental examination on the heterogeneity parameter Cv of earthquake precursors*

    Institute of Scientific and Technical Information of China (English)

    王凯英; 马胜利; 刘力强; 马瑾

    2002-01-01

    Two rock samples with different structures and materials were deformed under a biaxial loading system, and multi-point strain measurements were performed for each sample. The distribution of strain anomalies during the deformation and the instability process were analyzed by using Cv value put forward by WANG Xiao-qing and CHEN Xue-zhong, et al, a parameter to describe the heterogeneous distribution of earthquake precursors, so as to examine the method of Cv value and to explore its physical meaning experimentally. The result shows that the change of Cv value is correlated to the change of deformation characteristics and is an effective parameter to describe the heterogeneity of precursor distribution. Cv value increases firstly and then decreases before the instability, and the instability occurs when Cv value decreases to the level before increasing. This indicates that Cv value may be a useful parameter for earthquake prediction.

  11. Information characteristics of ground fluid precursors of strong continental earthquakes

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    It has become seismologist(s common view to attach importance to the study of the characteristics about the relationship among the space distribution of precursory anomalous stations, active structure, deep rock character, and different kinds of earthquakes. In this paper, the information characteristics of ground fluid precursors are analyzed with a few examples of earthquakes. The result shows that information characteristics of ground fluid precursors mainly demonstrate, temporally stage and acceleration pattern, specially, swarm and concurrence feature. It is a key scientific problem, we propose, to give deep study on the stage and concurrence pattern for realizing the seismogenic process as well as making relatively correct prediction to the potential earthquake focus and the occurrence time.

  12. Fabrication of Tungsten Carbide Nanoparticles from Refluxing Derived Precursor

    Institute of Scientific and Technical Information of China (English)

    WEN Jiqiu; LI Yongdi; MENG Xiaopeng; YIN Guangfu; YAO Yadong

    2015-01-01

    Tungsten carbide (WC) nanoparticles were fabricated from a novel refluxing-derived precursor. The precursor was prepared by acid hydrolysis of Na2WO4 with concentrated HCl in water followed by refluxing with ethanol and n-Dedocane, respectively. Then it was heat-treated to 1 200℃for 2 h in vacuum to obtain WC nanoparticles. X-ray studies reveal the formation of hexagonal tungsten carbide and the grain size of 24.3 nm. SEM image shows WC nanoparticles with particle size of 20-60 nm. Long time refluxing results in alkane dehydrogenation and coke formation. The coke is the carbon source in the carbothermal reduction reaction. The novel route of two-stage refluxing is quite general and can be applied in the synthesis of similar carbides.

  13. Preparation of tantalum carbide from an organometallic precursor

    Energy Technology Data Exchange (ETDEWEB)

    Souza, C.P. [Rio Grande do Norte Univ., Natal, RN (Brazil). Programa de Pos-graduacao em Geoquimica. Lab. de Termodinamica e Reatores]. E-mail: carlson at ufrnet.ufrn.br; Favotto, C.; Satre, P.; L' Honore, A.; Roubin, M. [Universite du Toulon et de Var B.P. (France). Equipe der Materiaux a Finalite Specifique. Lab. de Physicochimie du Materiaux et du Milieu Marin]. E-mail: roubin at univ-tln.fr

    1999-03-01

    In this work we have synthesized an organometallic oxalic precursor from tantalum oxide. This oxide was solubilized by heating with potassium hydrogen sulfate. In order to precipitate Ta{sub 2} O{sub 5} nH{sub 2}O, the fused mass obtained was dissolved in a sulfuric acid solution and neutralized with ammonia. The hydrated tantalum oxide precipitated was dissolved in an equimolar solution of oxalic acid/ammonium oxalate. The synthesis and the characterization of the tantalum oxalic precursor are described. Pyrolysis of the complex in a mixture of hydrogen and methane at atmospheric pressure was studied. The gas-solid reaction made it possible to obtain tantalum carbide, Ta C, in the powder form at 1000 deg C. The natural sintering of Ta C powder in an inert atmosphere at 1400 deg C during 10 hours, under inert atmosphere made it possible to density the carbide to 96% of the theoretical value. (author)

  14. Magnetic and density spikes in cosmic ray shock precursors

    CERN Document Server

    Malkov, M A; Diamond, P H

    2011-01-01

    In shock precursors populated by accelerated cosmic rays (CR), the CR return current instability is believed to significantly enhance the pre-shock perturbations of magnetic field. We have obtained fully-nonlinear exact ideal MHD solutions supported by the CR return current. The solutions occur as localized spikes of circularly polarized Alfven envelopes (solitons, or breathers). As the conventional (undriven) solitons, the obtained magnetic spikes propagate at a speed $C$ proportional to their amplitude, $C=C_{A}B_{{\\rm max}}/\\sqrt{2}B_{0}$. The sufficiently strong solitons run thus ahead of the main shock and stand in the precursor, being supported by the return current. This property of the nonlinear solutions is strikingly different from the linear theory that predicts non-propagating (that is, convected downstream) circularly polarized waves. The nonlinear solutions may come either in isolated pulses (solitons) or in soliton-trains (cnoidal waves). The morphological similarity of such quasi-periodic soli...

  15. Characterization studies of purified HgI{sub 2} precursors

    Energy Technology Data Exchange (ETDEWEB)

    Schieber, M. E-mail: Schieber@vms.huji.ac.il; Zuck, A.; Sanguinetti, S.; Montalti, M.; Braiman, M.; Melekhov, L.; Nissenbaum, J.; Grilli, E.; Guzzi, M.; Turchetta, R.; Dulinski, W.; Husson, D.; Riester, J.L

    1999-06-01

    The ability of HgI{sub 2} powders, used as precursors in mercuric iodide crystal growth, to produce high-quality detectors may be predicted by non-destructive methods like photoluminescence. In fact, it is possible to correlate the presence and the intensity ratio of specific bands in the photoluminescence spectrum of a HgI{sub 2} crystal to its impurity content and stoichiometry. These quantities determine the detector grade that may be achieved using that starting material. Nine different HgI{sub 2} precursors, obtained by different purification methods, have been characterized. The lowest impurity content is achieved via poly-ethylene treatment, which gives also a powder of relatively good stoichiometric quality.

  16. Derivation of multipotent mesenchymal precursors from human embryonic stem cells.

    Directory of Open Access Journals (Sweden)

    2005-06-01

    Full Text Available BACKGROUND: Human embryonic stem cells provide access to the earliest stages of human development and may serve as a source of specialized cells for regenerative medicine. Thus, it becomes crucial to develop protocols for the directed differentiation of embryonic stem cells into tissue-restricted precursors. METHODS AND FINDINGS: Here, we present culture conditions for the derivation of unlimited numbers of pure mesenchymal precursors from human embryonic stem cells and demonstrate multilineage differentiation into fat, cartilage, bone, and skeletal muscle cells. CONCLUSION: Our findings will help to elucidate the mechanism of mesoderm specification during embryonic stem cell differentiation and provide a platform to efficiently generate specialized human mesenchymal cell types for future clinical applications.

  17. PREPARATION OF TANTALUM CARBIDE FROM AN ORGANOMETALLIC PRECURSOR

    Directory of Open Access Journals (Sweden)

    C. P. SOUZA

    1999-03-01

    Full Text Available In this work we have synthesized an organometallic oxalic precursor from tantalum oxide. This oxide was solubilized by heating with potassium hydrogen sulfate. In order to precipitate Ta2O5.nH2O, the fused mass obtained was dissolved in a sulfuric acid solution and neutralized with ammonia. The hydrated tantalum oxide precipitated was dissolved in an equimolar solution of oxalic acid/ammonium oxalate. The synthesis and the characterization of the tantalum oxalic precursor are described. Pyrolysis of the complex in a mixture of hydrogen and methane at atmospheric pressure was studied. The gas-solid reaction made it possible to obtain tantalum carbide, TaC, in the powder form at 1000oC. The natural sintering of TaC powder in an inert atmosphere at 1400°C during 10 hours, under inert atmosphere made it possible to densify the carbide to 96% of the theoretical value.

  18. Synthesis and Characterization of Poly(methylsilane) as Ceramic Precursor

    Institute of Scientific and Technical Information of China (English)

    Chen Lai; Zhang Feng-jun; Wu Shi; Sun Jin-liang; Ren Mu-su; Fan Xue-qi

    2005-01-01

    @@ 1Introduction Polysilanes are novel polymers with Si-Si catenation chain. They can be used as precursors for SiC ceramic, have important applications in anti-oxidation of C/C composites[1]. Poly(methylsilane)(PMS), which is anideal precursor to stoichiometric SiC, is synthesized by the sodium polycondensation reaction of monomer CH3SiHCl2. During the reaction, there is an initiation period. In this period there is no obvious exothermic reaction after dropping of monomer, then suddenly eruptive reaction arise and temperature goes up quickly. After the eruption, the polymerization can proceed smoothly. This phenomenon is harmful to scale-up. To solve this problem, we did relevant research, but the additive, crown ether, is expensive[2]. This paper describes the influence of naphthalene(NAPH) and p-dibromobenzene(DBB) on the reaction. Good effect is attained for these additives.

  19. Atomic scale simulation of carbon nanotube nucleation from hydrocarbon precursors.

    Science.gov (United States)

    Khalilov, Umedjon; Bogaerts, Annemie; Neyts, Erik C

    2015-12-22

    Atomic scale simulations of the nucleation and growth of carbon nanotubes is essential for understanding their growth mechanism. In spite of over twenty years of simulation efforts in this area, limited progress has so far been made on addressing the role of the hydrocarbon growth precursor. Here we report on atomic scale simulations of cap nucleation of single-walled carbon nanotubes from hydrocarbon precursors. The presented mechanism emphasizes the important role of hydrogen in the nucleation process, and is discussed in relation to previously presented mechanisms. In particular, the role of hydrogen in the appearance of unstable carbon structures during in situ experimental observations as well as the initial stage of multi-walled carbon nanotube growth is discussed. The results are in good agreement with available experimental and quantum-mechanical results, and provide a basic understanding of the incubation and nucleation stages of hydrocarbon-based CNT growth at the atomic level.

  20. Percolation-based precursors of transitions in extended systems

    Science.gov (United States)

    Rodríguez-Méndez, Víctor; Eguíluz M, Víctor M.; Hernández-García, Emilio; Ramasco, José J.

    2016-07-01

    Abrupt transitions are ubiquitous in the dynamics of complex systems. Finding precursors, i.e. early indicators of their arrival, is fundamental in many areas of science ranging from electrical engineering to climate. However, obtaining warnings of an approaching transition well in advance remains an elusive task. Here we show that a functional network, constructed from spatial correlations of the system’s time series, experiences a percolation transition way before the actual system reaches a bifurcation point due to the collective phenomena leading to the global change. Concepts from percolation theory are then used to introduce early warning precursors that anticipate the system’s tipping point. We illustrate the generality and versatility of our percolation-based framework with model systems experiencing different types of bifurcations and with Sea Surface Temperature time series associated to El Niño phenomenon.

  1. Technical note: Methionine, a precursor of methane in living plants

    OpenAIRE

    Lenhart, K.; F. Althoff; Greule, M.; F. Keppler

    2014-01-01

    When terrestrial plants were identified as producers of the greenhouse gas methane, much discussion and debate ensued, not only about their contribution to the global methane budget, but also with regard to the validity of the observation itself. Although the phenomenon has now become more accepted for both living and dead plants, the mechanism of methane formation in living plants remains to be elucidated and its precursor compounds identified. We made use of stable isoto...

  2. Technical Note: Methionine, a precursor of methane in living plants

    OpenAIRE

    Lenhart, K.; F. Althoff; Greule, M.; F. Keppler

    2015-01-01

    When terrestrial plants were identified as producers of the greenhouse gas methane, much discussion and debate ensued not only about their contribution to the global methane budget but also with regard to the validity of the observation itself. Although the phenomenon has now become more accepted for both living and dead plants, the mechanism of methane formation in living plants remains to be elucidated and its precursor compounds to be identified. We made use of stable iso...

  3. PROLIFERATIVE INFLAMMATORY ATROPHY: POTENTIAL PRECURSOR LESION FOR PROSTATIC ADENOCARCINOMA

    Directory of Open Access Journals (Sweden)

    Benedetti-Padrón Inés

    2014-01-01

    Full Text Available Introduction: Prostatic Intraepithelial neoplasia (PIN is currently considered as the only precursor lesion of prostate cancer (PCa; nevertheless, some years ago, it has been suspected that the atrophic lesions also might be involved in its carcinogenesis. In 1999, De Marzo prospered, the expression Proliferative Inflammatory Atrophy (PIA to denominate a lesion located in the peripheral area of the gland, with epithelial cells with high proliferative potential, frequently accompanied of inflammation that has been postulated as possible precursor lesion of PIN and PCa. Objective: To review the concepts about Proliferative Inflammatory Atrophy (PIA, its morphological, genetics and molecular characteristics and to explain the precursor capacity of PIN and PCa. Methods: Databases Pubmed, Sciencedirect, EBSCOhost and OvidSP were reviewed in search of studies, systematic reviews, consensus and meta-analyses with keywords: Proliferative Inflammatory Atrophy, Prostatic Atrophy, Prostatic Carcinoma, using as due date December of 2012. Results: Molecular disorders described in PIA support the beginning of these lesions in a context of oxidative stress, possibly caused by the surrounding inflammatory cells, which induce the expression of defense gene against the oxidative damage of the genome in some epithelial cells, while those that fail in the expression of these gene become vulnerable to oxidants and electrophiles, which do them prone to develop genetic disorders that will benefit their transformation in cells of PIN and PCa. The morphological association PIA-PIN/PCa points to a progressive relationship between these lesions.Conclusion: Topographic association and morphological transition of PIA with PIN and PCa have been observed. Besides, genetic, somatic and molecular disorders have been reported in PIA, similar to those observed in PIN and PCa due to it has been postulated as possible precursor lesion of both. Nevertheless, this approach is

  4. Follicular Dendritic Cells Emerge from Ubiquitous Perivascular Precursors

    OpenAIRE

    Krautler, Nike Julia; Kana, Veronika; Kranich, Jan; Tian, Yinghua; Perera, Dushan; Lemm, Doreen; Schwarz, Petra; Armulik, Annika; Browning, Jeffrey L.; Tallquist, Michelle; Buch, Thorsten; Oliveira-Martins, José B.; Zhu, Caihong; Hermann, Mario; Wagner, Ulrich

    2012-01-01

    The differentiation of follicular dendritic cells (FDC) is essential to the remarkable microanatomic plasticity of lymphoid follicles. Here we show that FDC arise from ubiquitous perivascular precursors (preFDC) expressing platelet-derived growth factor receptor β (PDGFRβ). PDGFRβ-Cre-driven reporter gene recombination resulted in FDC labeling, whereas conditional ablation of PDGFRβ+-derived cells abolished FDC, indicating that FDC originate from PDGFRβ+ cells. Lymphotoxin-α-overexpressing pr...

  5. Hemopoietic cell precursor responses to erythropoietin in plasma clot cultures

    Energy Technology Data Exchange (ETDEWEB)

    Kennedy, W.L.

    1979-01-01

    The time dependence of the response of mouse bone marrow cells to erythropoietin (Ep) in vitro was studied. Experiments include studies on the Ep response of marrow cells from normal, plethoric, or bled mice. Results with normal marrow reveal: (1) Not all erythroid precursors (CFU-E) are alike in their response to Ep. A significant number of the precursors develop to a mature erythroid colony after very short Ep exposures, but they account for only approx. 13% of the total colonies generated when Ep is active for 48 hrs. If Ep is active more than 6 hrs, a second population of erythroid colonies emerges at a nearly constant rate until the end of the culture. Full erythroid colony production requires prolonged exposure to erythropoietin. (2) The longer erythropoietin is actively present, the larger the number of erythroid colonies that reach 17 cells or more. Two distinct populations of immediate erythroid precursors are also present in marrow from plethoric mice. In these mice, total colony numbers are equal to or below those obtained from normal mice. However, the population of fast-responding CFU-E is consistently decreased to 10 to 20% of that found in normal marrow. The remaining colonies are formed from plethoric marrow at a rate equal to normal marrow. With increasing Ep exposures, the number of large colonies produced increases. From the marrow of bled mice, total erythroid colony production is equal to or above that of normal marrow. Two populations of colony-forming cells are again evident, with the fast-responding CFU-E being below normal levels. The lack of colonies from this group was compensated in bled mice by rapid colony production in the second population. A real increase in numbers of precursors present in this pool increased the rate of colony production in culture to twice that of normal marrow. The number of large colonies obtained from bled mice was again increased as the Ep exposure was lengthened. (ERB)

  6. Thin films by metal-organic precursor plasma spray

    International Nuclear Information System (INIS)

    While most plasma spray routes to coatings utilize solids as the precursor feedstock, metal-organic precursor plasma spray (MOPPS) is an area that the authors have investigated recently as a novel route to thin film materials. Very thin films are possible via MOPPS and the technology offers the possibility of forming graded structures by metering the liquid feed. The current work employs metal-organic compounds that are liquids at standard temperature-pressure conditions. In addition, these complexes contain chemical functionality that allows straightforward thermolytic transformation to targeted phases of interest. Toward that end, aluminum 3,5-heptanedionate (Al(hd)3), triethylsilane (HSi(C2H5)3 or HSiEt3), and titanium tetrakisdiethylamide (Ti(N(C2H5)2)4 or Ti(NEt2)4) were employed as precursors to aluminum oxide, silicon carbide, and titanium nitride, respectively. In all instances, the liquids contain metal-heteroatom bonds envisioned to provide atomic concentrations of the appropriate reagents at the film growth surface, thus promoting phase formation (e.g., Si-C bond in triethylsilane, Ti-N bond in titanium amide, etc.). Films were deposited using a Sulzer Metco TriplexPro-200 plasma spray system under various experimental conditions using design of experiment principles. Film compositions were analyzed by glazing incidence x-ray diffraction and elemental determination by x-ray spectroscopy. MOPPS films from HSiEt3 showed the formation of SiC phase but Al(hd)3-derived films were amorphous. The Ti(NEt2)4 precursor gave MOPPS films that appear to consist of nanosized splats of TiOCN with spheres of TiO2 anatase. While all films in this study suffered from poor adhesion, it is anticipated that the use of heated substrates will aid in the formation of dense, adherent films.

  7. Precursors of Professionalism in Senior-level Undergraduate Business Students

    OpenAIRE

    Nino, Lana Sami

    2012-01-01

    Understanding the professional identity of senior-level undergraduate business students may shed light on the rampant unethical acts of business managers in industry. Business education is the largest segment of undergraduate majors, constituting more than 20% of students in four-year institutions, year after year. To explain the professional identity of business students, this study uses prior theoretical frameworks to model the precursors of professionalism--"autonomy of judgment," "desir...

  8. Evidence for intramolecular self-cleavage of picornaviral replicase precursors.

    OpenAIRE

    Palmenberg, A C; Rueckert, R R

    1982-01-01

    It has previously been shown that when encephalomyocarditis viral RNA is translated in cell-free extracts of rabbit reticulocytes, it synthesizes a virus-coded protease, p22, which is derived by cleavage of a precursor protein, C. Protein C is shown here to be cleaved by two different mechanisms, which were distinguished by their sensitivity to dilution. One mechanism was sensitive to dilution; the other was not. The biphasic cleavage behavior was unchanged by diluting incubation mixtures wit...

  9. Prospective use of skin-derived precursors in neural regeneration

    Institute of Scientific and Technical Information of China (English)

    LU Xiao-cheng; TAO Yi; LI Li-xin

    2012-01-01

    Objective To review recent studies concerning the origins of skin-derived precursors (SKPs),their differentiation characteristics,and their potential application in neural regenerative medicine.Data sources Data were retrieved from studies reported in PubMed published between April,1974 and June,2012.The search terms used were "skin-derived precursors","stem cells",and "neural diseases".Study selection Articles were included in the review if they were relevant to SKPs as stem cells,as well as their applications in neural regenerative medicine,such as in the treatment of spinal cord injury,Parkinson's disease,spinal muscular atrophy and Shah-Waardenburg syndrome.Results SKPs are a novel population of neural crest-derived precursors that arise during embryogenesis and persist into adulthood.They can generate both neural cells and mesodermal lineage cells (including smooth muscle cells and adipocytes).Compared with other stem cells,SKPs are abundant in adult skin,can differentiate easily into neural cells,and are not associated with any ethical controversies.Conclusion SKPs may provide an alternative source of stem cells to embryonic stem cells for transplantation therapy for neurological diseases.

  10. LWIR hyperspectral imaging application and detection of chemical precursors

    Science.gov (United States)

    Lavoie, Hugo; Thériault, Jean-Marc; Bouffard, François; Puckrin, Eldon; Dubé, Denis

    2012-10-01

    Detection and identification of Toxic industrial chemicals (TICs) represent a major challenge to protect and sustain first responder and public security. In this context, passive Hyperspectral Imaging (HSI) is a promising technology for the standoff detection and identification of chemical vapors emanating from a distant location. To investigate this method, the Department of National Defense and Public Safety Canada have mandated Defense Research and Development Canada (DRDC) - Valcartier to develop and test Very Long Wave Infrared (VLWIR) HSI sensors for standoff detection. The initial effort was focused to address the standoff detection and identification of toxic industrial chemicals (TICs), surrogates and precursors. Sensors such as the Improved Compact ATmospheric Sounding Interferometer (iCATSI) and the Multi-option Differential Detection and Imaging Fourier Spectrometer (MoDDIFS) were developed for this application. This paper presents the sensor developments and preliminary results of standoff detection and identification of TICs and precursors. The iCATSI and MoDDIFS sensors are based on the optical differential Fourier-transform infrared (FTIR) radiometric technology and are able to detect, spectrally resolve and identify small leak at ranges in excess of 1 km. Results from a series of trials in asymmetric threat type scenarios are reported. These results serve to establish the potential of passive standoff HSI detection of TICs, precursors and surrogates.

  11. Spectroscopy Study of Synthetic Forsterite Obtained from Zeolite Precursors

    Directory of Open Access Journals (Sweden)

    Subotić, B.

    2008-02-01

    Full Text Available Important ceramics materials are prepared from aluminosilicate based precursors using novel methods, offering at the same time a better control over many important properties. Forsterite, due to its good refractoriness with melting point at 2163 K, excellent electrical insulation properties even at high temperatures, low dielectric permittivity, thermal expansion and chemical stability, is a material of interest to engineers and designers especially as an active medium for tuneable laser and is also a material of interest to SOFC (Solid oxide fuel cells manufacturers. The aim of this study is to investigate the synthesis of crystalline forsterite using different zeolite precursors previously activated by ball milling. Synthetic forsterite was synthesized from different zeolite precursors and MgO combining highenergy ball milling and thermal treatment of the mixture under determined conditions of time and temperature for each operation. In this research are studied the solid-state phase transformations taking place at temperatures below 1273 K. The obtained products were characterized using different spectroscopy techniques in comparison with surface analysis method and X-ray diffraction.

  12. Structural analysis of the precursor pseudogap in cuprate superconductors

    Science.gov (United States)

    Suzuki, Sokichi

    2016-10-01

    We investigate the precursor pseudogap (PP) state that emerges on the lower temperature side of the pseudogap phase in cuprate superconductors based on the characteristic layer structure. The coherence among layers in the electronic state may be broken by low energy thermal interactions, whereas the coherence within the layers remains in the phase above the superconducting (SC) phase on account of strongness of the bonding. In this state, the two-electron energy gain (TEG) is also larger than that of SC state and the one-electron energy gain (OEG) is smaller than that of the SC state. We call this incoherent ensemble of in-layer states the in-layer electronic state system (IESS). The PP state is a crossover state between IESS and the normal pseudogap (NP) state, which appears on the upper temperature side, because the d-wave pairing symmetry in cuprates inverts the sign of the difference of the total electronic energy gain between the IESS and the NP state around the nodal region, even though it is positive overall. We perform our analysis at the mean field level. We show that the relationships among the SC gap, the gap of in-layer state, and the transition temperatures in the relevant phases are compatible with existing experimental data. The proposed precursor state requires pairing models to make the SC interactions three-dimensional beyond a single layer, although the precursors have in-layer properties.

  13. Observations of Electromagnetic Whistler Precursors at Supercritical Interplanetary Shocks

    Science.gov (United States)

    Wilson, L. B., III; Koval, A.; Szabo, Adam; Breneman, A.; Cattell, C. A.; Goetz, K.; Kellogg, P. J.; Kersten, K.; Kasper, J. C.; Maruca, B. A.; Pulupa, M.

    2012-01-01

    We present observations of electromagnetic precursor waves, identified as whistler mode waves, at supercritical interplanetary shocks using the Wind search coil magnetometer. The precursors propagate obliquely with respect to the local magnetic field, shock normal vector, solar wind velocity, and they are not phase standing structures. All are right-hand polarized with respect to the magnetic field (spacecraft frame), and all but one are right-hand polarized with respect to the shock normal vector in the normal incidence frame. They have rest frame frequencies f(sub ci) < f much < f(sub ce) and wave numbers 0.02 approx < k rho (sub ce) approx <. 5.0. Particle distributions show signatures of specularly reflected gyrating ions, which may be a source of free energy for the observed modes. In one event, we simultaneously observe perpendicular ion heating and parallel electron acceleration, consistent with wave heating/acceleration due to these waves. Al though the precursors can have delta B/B(sub o) as large as 2, fluxgate magnetometer measurements show relatively laminar shock transitions in three of the four events.

  14. Hydrokinetic simulations of nanoscopic precursor films in rough channels

    CERN Document Server

    Chibbaro, S; Binder, K; Dimitrov, D; Diotallevi, F; Milchev, A; Succi, S

    2009-01-01

    We report on simulations of capillary filling of high-wetting fluids in nano-channels with and without obstacles. We use atomistic (molecular dynamics) and hydrokinetic (lattice-Boltzmann) approaches which point out clear evidence of the formation of thin precursor films, moving ahead of the main capillary front. The dynamics of the precursor films is found to obey a square-root law as the main capillary front, z^2(t) ~ t, although with a larger prefactor, which we find to take the same value for the different geometries (2D-3D) under inspection. The two methods show a quantitative agreement which indicates that the formation and propagation of thin precursors can be handled at a mesoscopic/hydrokinetic level. This can be considered as a validation of the Lattice-Boltzmann (LB) method and opens the possibility of using hydrokinetic methods to explore space-time scales and complex geometries of direct experimental relevance. Then, LB approach is used to study the fluid behaviour in a nano-channel when the prec...

  15. Dipole collapse and reversal precursors in a numerical dynamo

    Science.gov (United States)

    Olson, Peter; Driscoll, Peter; Amit, Hagay

    2009-03-01

    Precursors to extreme geomagnetic field changes are examined in a numerical dynamo with a reversing dipolar magnetic field. A dynamo model with compositional convection in a rotating spherical shell produces a strongly dipolar external magnetic field over 6 Myr of simulated paleomagnetic time, with stable polarity epochs and occasional dipole collapses, some of which result in polarity reversals or dipole axis excursions. We analyze the model behavior during two dipole collapses, one that leads to a polarity reversal and one that does not, focusing on observable precursors. Reversed magnetic field induced in the dynamo interior by intermittent convective variability is the primary cause of dipole collapse. Spots of reversed magnetic flux emerge on the outer boundary at an early stage, then re-emerge with greater intensity at the height of the collapse. The energy in the external field cascades to higher harmonics as these reversed patches appear. Butterfly diagrams showing the reversed and normal flux contributions to the axial dipole reveal poleward migration of the patches during dipole collapse. Axial dipole reduction by precursory reversed flux is several times larger in the reversing case, compared to the non-reversing case. A butterfly diagram of the geomagnetic field since 1840 shows high latitude reversed flux emerging on the core-mantle boundary. Although the reversed geomagnetic flux is presently too weak to be labeled a reversal precursor, it is consistent with early stage dipole collapse in the dynamo model.

  16. Development of techniques for tagging precursor and essential chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Swansiger, W.A.; Shepodd, T.J. [Sandia National Labs., Livermore, CA (United States); Phillips, M.L.F. [Sandia National Labs., Albuquerque, NM (United States)

    1994-01-01

    The ability to identify the manufacturers and distributors of chemicals seized in raids of illicit drug labs would be of great value in controlling the diversion of these chemicals. We developed a tagging scheme based on the addition of sub-ppM concentrations of various combinations of rare-earth elements to the target chemicals and evaluated a number of techniques for detecting the tags. We developed soluble tags for tagging liquids and selected Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) as the preferred detection technique. We developed insoluble tags for tagging solids and developed methods to analyze them and mix them into solid precursors. We have successfully demonstrated the tagging of several solvents and two of the precursor chemicals used in one of the most popular clandestine methamphetamine syntheses (ephedrine reacting with hydriodic acid/red phosphorus). The tagging scheme is capable of yielding tens of thousands of signatures (using holmium as an internal standard and up to 9 rare-earths at up to 3 concentrations yields 3{sup 9} {minus} 1 = 19,682 signatures) and is applicable to most of the chemicals on the precursor and essential chemicals list. In the concentrations employed, the tags are safe enough to be added to pharmaceuticals and cheap enough to tag tanker loads of chemicals.

  17. X Ray Precursors in SGRs Precessing Gamma Jet Tails

    CERN Document Server

    Fargion, D

    2002-01-01

    Weak isolated X-ray precursor events before the main Gamma Ray Burst, GRB, and also rare Soft Gamma Repeaters, SGR, events are in complete disagreement with any Fireball, or Magnetar, one-shoot explosive scenarios. Fireball model in last two years has been deeply modified into a fountain beamed Jet exploding and interacting on external shells to explain GRB fine time structure. On the contrary earlier we proposed a unified scenario for both GRBs-SGRs where a precessing Gamma Jet (of different intensity) and its geometrical beaming is the source of both GRB and SGRs wide morphology. GRBs are peaked SNs Jet spinning and precessing observed along the thin Jet axis. Their mysterious weak X precursors bursts, corresponding to non-negligible energy powers, up to million Supernova ones for GRB, are gamma Jet tails beamed off-axis, observed at X-Ray tails. They are rare, about (3-6)% of all GRBs, but not unique at all. Comparable brief X-ray precursor flashes occurred in rarest and most detailed SGRs events as the 27...

  18. Characterization of dental cement obtained from a glass prepared by the polymeric precursor method; Caracterizacao de cimento odontologico obtido a partir de um vidro preparado pelo metodo dos precursores polimericos

    Energy Technology Data Exchange (ETDEWEB)

    Bertolini, Marcio Jose; Zaghete, Maria Aparecida; Gimenes, Rossano; Paiva-Santos, Carlos de Oliveira [UNESP, Araraquara, SP (Brazil). Inst. de Quimica]. E-mail: marciobert@yahoo.com.br; Palma-Dibb, Regina Guenka [Sao Paulo Univ., Ribeirao Preto, SP (Brazil). Faculdade de Odontologia

    2005-09-15

    Glass ionomer cements are glass and polymer composite materials. These materials currently find use in dentistry. The purpose of this work is to obtain glass powders based on the composition 4.5SiO{sub 2} - 3Al{sub 2}O{sub 3} - 2CaO to be used in dentistry. The powders were prepared by a chemical route at 700 deg C. The properties of glass ionomer cements obtained from powders prepared at 700 deg C were studied. Diametral tensile strength and microhardness were evaluated for the experimental glass ionomer cements and a commercial material. It was concluded that the properties of experimental cements were similar to those of the commercial ones. (author)

  19. Dificuldades no relacionamento professor/aluno: um desafio a superar

    Directory of Open Access Journals (Sweden)

    Fábia Moreira Squarça Cabral

    2004-12-01

    Full Text Available O relacionamento professor - aluno é um tema que vem sendo investigado, através de diferentes estratégias metodológicas. Este trabalho trata a questão a partir da visão dos atores que participam do processo de ensino e aprendizagem, tendo por base professores e alunos de uma 8ª Série, de uma escola estadual da região de Londrina, Paraná, que responderam a um questionário, elaborado com questões abertas. Um estudo comparativo entre as informações fornecidas pelos dois grupos de participantes elucida momentos de tensão e de entrosamento entre estes personagens que constroem e reconstroem vivências e experiências capazes de expor valores e modos de vida. A luta pela sobrevivência de objetos alvo da escola, a aprendizagem e o conhecimento, é de interesse de todos, que consciente ou inconscientemente, participam do processo em busca de um caminho harmônico de convivência e crescimento.

  20. Jornal: um modo de presença

    Directory of Open Access Journals (Sweden)

    Norma Discini

    2008-11-01

    Full Text Available Considerando o jornal uma totalidade de discursos, que supõe uma unidade de sentido, de modo a apresentar o todo em cada parte, é depreendido um modo de presença da enunciação, sempre pressuposta a qualquer enunciado, a partir da leitura de primeiras páginas e da chamada página de opinião, com os gêneros "editorial" e "charge". Um ethos, um estilo, emerge para cada um destes dois jornais: Folha de S. Paulo e O Estado de S. Paulo. Palavras-chave enunciação, enunciado, totalidade, ethos Abstract Considering the newspaper as a totality of discourses, which implies a unity of meaning, so as to allow the participation of the whole in each part, it is apprehended a kind of presence of the enunciation, always presupposed to any text, from the reading of first pages and the so-called opinion page, with the genres "editorial" and "charge". An ethos, a style, emerges to each one of these newspapers: Folha de S. Paulo and O Estado de S. Paulo. Key words enunciation, text, totality, ethos

  1. George Herbert Mead, Um, osoba i društvo

    OpenAIRE

    Bačeković, Alica

    2004-01-01

    Prikaz knjige George Herbert Mead, Um, osoba i društvo sa stajališta socijalnog biheviorista, priredio i uvod napisao Charles W. Morris, s engleskoga preveo Srđan Dvornik, Naklada Jesenski i Turk, Hrvatsko sociološko društvo, Zagreb 2003, xxx + 392 str

  2. Um século à espera de regras

    Directory of Open Access Journals (Sweden)

    HELOÍSA RODRIGUES FERNANDES

    1996-06-01

    Full Text Available Ao comemorar cem anos da publicação de uma das obras de fundação da Sociologia, As Regras do método sociológico, o artigo retoma a herança durkheimiana problematizando especialmente um dos seus principais legados aos habitantes desse século XX: o conceito de anomia.

  3. Liquid precursor for deposition of indium selenide and method of preparing the same

    Energy Technology Data Exchange (ETDEWEB)

    Curtis, Calvin J.; Miedaner, Alexander; van Hest, Marinus Franciscus Antonius Maria; Ginley, David S.; Hersh, Peter A.; Eldada, Louay; Stanbery, Billy J.

    2015-09-22

    Liquid precursors containing indium and selenium suitable for deposition on a substrate to form thin films suitable for semiconductor applications are disclosed. Methods of preparing such liquid precursors and method of depositing a liquid precursor on a substrate are also disclosed.

  4. Desenvolvimento e avaliação de um interface com o utilizador para um sistema de escalonamento

    Directory of Open Access Journals (Sweden)

    Jesus Piairo

    2013-06-01

    Full Text Available Este artigo descreve o processo de desenvolvimento e avaliação de um interface com o utilizador para um sistema de escalonamento. Pretende-se disponibilizar ao utilizador, além de uma forma gráfica e interativa de definir problemas de escalonamento, uma forma interativa de visualizar e adaptar um plano de escalonamento. A concretização destes objetivos foi alcançada através de um protótipo modular desenvolvido com base numa metodologia centrada na avaliação de usabilidade: Metodologia em Estrela. De modo a avaliar a usabilidade do protótipo, realizou-se uma sessão de avaliação que permitiu não só avaliar a facilidade de utilização, mas também observar as diferentes formas de interação proporcionada por cada participante.

  5. The effect of precursors salts on surface state of Pd/Al2O3 and Pd/CeO2/Al2O3 catalysts

    Directory of Open Access Journals (Sweden)

    André L. Guimarães

    2004-12-01

    Full Text Available The influence of the precursors on the promoting effect of ceria on Pd/Al2O3 catalyst, when ceria is coated over alumina was studied. The reaction of propane oxidation proceeded under different feed conditions and the surface active sites were characterized by X-ray photoelectron spectroscopy (XPS and in situ diffuse reflectance spectroscopy (DRS. XPS and DRS results show that PdO/Pd0 interface are the active sites independent of the precursor, while the catalysts containing CeO2 showed formation of palladium species in the highest oxidation state, probably PdO2 (338 eV after the oxidation of propane. Besides, the O/Al and O/Ce ratios evidenced the increase of oxygen storage in the presence of CeO2. In addition, the precursor acetylacetonate favors the oxygen storage in the lattice.Estudo da influência dos precursores sobre os catalisadores de Pd/Al2O3 promovidos com céria ancorado sobre a alumina. A oxidação do propano foi feita sob diferentes condições de alimentação sendo caracterizados os sítios superficiais por Espectroscopia Fotoeletrônica de raios X (XPS e por Refletância Difusa em ''situ''. Resultados de XPS e DRS mostraram a formação de interfaces de PdO/Pd0 como sendo os sítios ativos, independentes do precursor utilizado na preparação, enquanto que os catalisadores contendo CeO2 mostraram a formação de espécies de paládio com estado de oxidação mais altos, provavelmente PdO2 (338 eV após a oxidação do propano. Além disso, as razões O/Al e O/Ce evidenciaram um aumento de oxigênio armazenado na presença de CeO2. O precursor acetilacetonato favoreceu o armazenamento de oxigênio na rede.

  6. A fonética e seus precursores

    Directory of Open Access Journals (Sweden)

    Elvira Wanda Vagones

    2001-01-01

    Full Text Available

    Fazemos neste artigo um levantamento histórico sucinto das principais investigações dos autores que se interessaram pelo estudo da linguagem humana no plano de expressão, isto é, pelo estudo dos sons lingüísticos, assim como daqueles pesquisadores que, trabalhando com outras ciências (por exemplo, a fisiologia, a física, contribuíram indiretamente para o progresso dos estudos fonéticos.

  7. Glutamine: precursor or nitrogen donor for citrulline synthesis?

    Science.gov (United States)

    Marini, Juan C; Didelija, Inka Cajo; Castillo, Leticia; Lee, Brendan

    2010-07-01

    Although glutamine is considered the main precursor for citrulline synthesis, the current literature does not differentiate between the contribution of glutamine carbon skeleton vs. nonspecific nitrogen (i.e., ammonia) and carbon derived from glutamine oxidation. To elucidate the role of glutamine and nonspecific nitrogen in the synthesis of citrulline, l-[2-(15)N]- and l-[5-(15)N]glutamine and (15)N-ammonium acetate were infused intragastrically in mice. The amino group of glutamine labeled the three nitrogen groups of citrulline almost equally. The amido group and ammonium acetate labeled the ureido and amino groups of citrulline, but not the delta-nitrogen. D(5)-glutamine also infused in this arm of the study, which traces the carbon skeleton of glutamine, was utilized poorly, accounting for only 0.2-0.4% of the circulating citrulline. Dietary glutamine nitrogen (both N groups) incorporation was 25-fold higher than the incorporation of its carbon skeleton into citrulline. To investigate the relative contributions of the carbon skeleton and nonspecific carbon of glutamine, arginine, and proline to citrulline synthesis, U-(13)C(n) tracers of these amino acids were infused intragastrically. Dietary arginine was the main precursor for citrulline synthesis, accounting for approximately 40% of the circulating citrulline. Proline contribution was minor (3.4%), and glutamine was negligible (0.4%). However, the glutamine tracer resulted in a higher enrichment in the ureido group, indicating incorporation of nonspecific carbon from glutamine oxidation into carbamylphosphate used for citrulline synthesis. In conclusion, dietary glutamine is a poor carbon skeleton precursor for the synthesis of citrulline, although it contributes both nonspecific nitrogen and carbon to citrulline synthesis.

  8. Precursor times of abnormal b-values prior to mainshocks

    Science.gov (United States)

    Wang, Jeen-Hwa; Chen, Kou-Cheng; Leu, Peih-Lin; Chang, Chien-Hsin

    2016-07-01

    Seismic observations exhibit the presence of abnormal b-values prior to numerous earthquakes. The time interval from the appearance of abnormal b-values to the occurrence of mainshock is called the precursor time. There are two kinds of precursor times in use: the first one denoted by T is the time interval from the moment when the b-value starts to increase from the normal one to the abnormal one to the occurrence time of the forthcoming mainshock, and the second one denoted by T p is the time interval from the moment when the abnormal b-value reaches the peak one to the occurrence time of the forthcoming mainshock. Let T* be the waiting time from the moment when the abnormal b-value returned to the normal one to the occurrence time of the forthcoming mainshock. The precursor time, T (usually in days), has been found to be related to the magnitude, M, of the mainshock expected in a linear form as log( T) = q + rM where q and r are the coefficient and slope, respectively. In this study, the values of T, T p , and T* of 45 earthquakes with 3 ≤ M ≤ 9 occurred in various tectonic regions are compiled from or measured from the temporal variations in b-values given in numerous source materials. The relationships of T and T p , respectively, versus M are inferred from compiled data. The difference between the values of T and T p decreases with increasing M. In addition, the plots of T*/ T versus M, T* versus T, and T* versus T- T* will be made and related equations between two quantities will be inferred from given data.

  9. Quantitation of natural killer cell precursors in man.

    Science.gov (United States)

    Gharehbaghian, Ahmad; Haque, K M Gausul; Truman, Carol; Newman, John; Bradley, Benjamin A

    2002-02-01

    A technique was developed to measure the frequency of natural killer cell precursors (NKpf) in human peripheral blood mononuclear cell (PBMC) samples. Functional maturity of NK cells was reflected in their ability to lyse target cells from the K562 cell line. During the development of the technique, venous blood was taken from one healthy adult and assayed at different times to avoid individual variation. The technique was based on the principle of limiting dilution analysis. The NKpf assay was set up with a range of cell dilutions from 40,000 to 625 per 100 microl/well in 96-well culture plates. At the end of the culture period, the K562 cell line labelled with europium (Eu-K562) was added and the Eu-release was measured in culture supernatants using time-resolved fluorometry. The NKpf value differed between individuals and was influenced by the length of time in culture, being maximal at day 5. Maturation of NKp required the continuous presence of recombinant interleukin 2 (rIL-2), or rIL-15, both being equally effective. In the absence of cytokines, the functional NK cells declined rapidly beyond 24 h in culture. Irradiated allogeneic cells appeared to substitute in part for cytokines, but the numbers of allo-activated NKpf were lower than those observed when allo-activated NKpf were cultured with rIL-2. This suggested selective activation by the allogeneic stimulus of subsets of NKp or rIL-2-rescue of NKp subsets destined for apoptotic cell death. Alternatively, the increased frequency could have been attributable to activation of precursors of natural killer-T cells (NK-Tp). This assay is suitable for estimating the total number of precursors of functional NK cells in the blood of patients. PMID:11792377

  10. Chondrule precursors and cooling paths: The sulfur evidence

    Science.gov (United States)

    Zanda, B.; Yu, Y.; Bourot-Denise, M.; Hewins, R. H.; Connolly, H. C., Jr.

    1994-01-01

    The behavior of moderately volatile elements (Na and S) is controversial but critical in understanding chondrule precursors and heating processes. Sulfide appeared to be present in most chondrules, but S should have been vaporized during chondrule formation. In fact, S is extensively redistributed in the course of metamorphism, and its abundance at the end of chondrule formation can only be inferred from the least equilibrated chondrites. Our study of 530 chondrules from Renazzo (CR2) and Semarkona (LL3.0) shows partial volatilization of S during chondrule formation and our melting experiments define conditions for total loss or partial retention of S.

  11. Surface reconstruction precursor to melting in Au309 clusters

    Directory of Open Access Journals (Sweden)

    Fuyi Chen

    2011-09-01

    Full Text Available The melting of gold cluster is one of essential properties of nanoparticles and revisited to clarify the role played by the surface facets in the melting transition by molecular dynamics simulations. The occurrence of elaborate surface reconstruction is observed using many-body Gupta potential as energetic model for 309-atom (2.6 nm decahedral, cuboctahedral and icosahedral gold clusters. Our results reveal for the first time a surface reconstruction as precursor to the melting transitions. The surface reconstruction lead to an enhanced melting temperature for (100 faceted decahedral and cuboctahedral cluster than (111 faceted icosahedral gold cluster, which form a liquid patch due to surface vacancy.

  12. Silylaryl Halides Can Replace Triflates as Aryne Precursors.

    Science.gov (United States)

    Mesgar, Milad; Daugulis, Olafs

    2016-08-01

    Silylaryl bromides and iodides can be prepared in one step from commercially available starting materials. Arynes can be generated from these compounds under conditions nearly identical to those employed for silylaryl triflates. Three distinct transformations, ortho-arylation of N-tritylanilines, intermolecular addition of arynes to amides, and reaction of ureas with arynes, were shown to be successful for the new aryne precursors. The main advantage of silylaryl halides relative to silyl aryl triflates is their one-step preparation from commercially available starting materials. PMID:27415183

  13. Superhydrophobic Ceramic Coatings by Solution Precursor Plasma Spray

    Science.gov (United States)

    Cai, Yuxuan; Coyle, Thomas W.; Azimi, Gisele; Mostaghimi, Javad

    2016-04-01

    This work presents a novel coating technique to manufacture ceramic superhydrophobic coatings rapidly and economically. A rare earth oxide (REO) was selected as the coating material due to its hydrophobic nature, chemical inertness, high temperature stability, and good mechanical properties, and deposited on stainless steel substrates by solution precursor plasma spray (SPPS). The effects of various spraying conditions including standoff distance, torch power, number of torch passes, types of solvent and plasma velocity were investigated. The as-sprayed coating demonstrated a hierarchically structured surface topography, which closely resembles superhydrophobic surfaces found in nature. The water contact angle on the SPPS superhydrophobic coating was up to 65% higher than on smooth REO surfaces.

  14. Isotopic and geochemical precursors of earthquakes and volcanic eruptions

    International Nuclear Information System (INIS)

    Radon 222 seems to be one of the most promising precursors and is the tracer for which more data are available: according to statistics elaborated in China, 70% of earthquakes are preceded by radon anomalies detectable in soil, air and/or in groundwater. Also other changes of the fluid chemical composition and variations of 3He/4He, 2H/1H, 13C/12C, 18O/16O isotopic ratios have been detected. Among these indicators one can mention variations in concentration and/or isotopic ratios of hydrogen, helium, carbon, oxygen, neon, radon, radium and uranium. Refs, figs, tabs

  15. CVD OF COPPER USING CuCl AS PRECURSOR

    OpenAIRE

    Lampe-Önnerud, C.; HÅrsta, A.; Jansson, U.

    1991-01-01

    Chemical vapour deposition of copper using CuCl as the copper precursor has been investigated. It was found that the evaporation of CuCl from a solid powder was a critical step. The evaporation process was strongly dependent on mainly two factors, deviations from equilibrium upon evaporation and formation of hydroxychloride on the powder surface. The copper deposition was investigated for two different gas mixtures, Ar/CuCl and Ar/CuCl/H2, and two different substrates, SiO2 and Si(111). On th...

  16. One-dimensional Nanostructured Materials From Organic Precursor

    Institute of Scientific and Technical Information of China (English)

    K. F. Cai

    2005-01-01

    @@ 1Introduction One-dimensional nanostructured materials, such as nanowires, nanobelts, nanotubes and nanocables have been attracting a great research interest in the last decade due to their superior electrical, optical, mechanical and thermal properties, and many methods have been explored to synthesis of the materials, e.g., arc discharge, laser ablation, chemical vapor deposition, thermal evaporation, sol-gel method, template method and so on. In this work, we present a novel and simple method to one-dimensional nanostructured materials by pyrolysis of organic precursor.

  17. Synthesis of carbon nanotubes using natural carbon precursor: Castor oil

    Science.gov (United States)

    Raziah, A. Z.; Junizah, A. R.; Saifuddin, N.

    2012-09-01

    Castor oil has long been an article of commerce due to its versatility as it is widely used as a starting material for many industrial chemical products because of its unique structure. In this study, carbon nanotubes has been synthesized by thermal decomposition of castor oil in nitrogen atmosphere at 300-400δC using custom-made microwave processing unit. The precursor material was catalyzed by iron clusters originating from the addition of ferrocene. The morphology and characterization of the CNTs were studied and discussed by transmission electron microscopy (TEM).

  18. Precursors for the preparation of superconducting thin films via MOCVD

    International Nuclear Information System (INIS)

    This paper reports on the synthesis and characterization of some Ba-acetylacetonato derivatives and of Ba isopropoxide Ba(OPri)2 that have been carried out under oxygen and moisture free conditions in order to obtain pure materials. Ba(OPri)2 appears as a convenient starting material in the organometallic chemistry of barium. In addition the potential use of Tl(η5 - C5H5) as Tl precursor has been explored by studying the products of its thermal decomposition under vacuum and in oxygen atmosphere

  19. Radon anomaly as a potentially powerful precursor in earthquake prediction

    International Nuclear Information System (INIS)

    Radon anomaly is one of the strongest precursors of seismic activities leading to disastrous earthquake. With recent series of earthquakes in the Himalayan region, there is a renewed interest in forecasting such events. It is believed that monitoring of radon concentration along and across the active geological faults might provide us significantly clear signals as forerunner of the impending earthquake, which may be used to save precious lives and loss of property. A brief review of the concept, techniques and some promising results on the future possibilities of utilizing radon anomalies in earthquake prediction will be presented and discussed. (author)

  20. X Ray Precursors in SGRs: Precessing Gamma Jet Tails

    OpenAIRE

    Fargion, Daniele

    2001-01-01

    Weak isolated X-ray precursor events before the main Gamma Ray Burst, GRB, and also rare Soft Gamma Repeaters, SGR, events are in complete disagreement with any Fireball, or Magnetar, one-shoot explosive scenarios. Fireball model in last two years has been deeply modified into a fountain beamed Jet exploding and interacting on external shells to explain GRB fine time structure. On the contrary earlier we proposed a unified scenario for both GRBs-SGRs where a precessing Gamma Jet (of different...

  1. Imaging Transition Zone Thickness Beneath South America from SS Precursors

    Science.gov (United States)

    Schmerr, N.; Garnero, E.

    2006-12-01

    We image detailed upper mantle discontinuity structure beneath a number of geologically active regions, including the South American subduction zone, the Scotia plate subduction zone, and several volcanic hotspots (e.g., the Galapagos Islands), in a region ~10,000 km by 10,000 km wide, spanning 70° S to 20° N and 20° W to 110° W. Precursors to the seismic phase SS are analyzed, which form as a result of underside reflections off seismic discontinuities beneath the midpoint of the SS path and are highly sensitive to discontinuity depth and sharpness. Our SS dataset consists of over 15,000 high-quality transverse component broadband displacement seismograms collected from the Incorporated Research Institutions for Seismology (IRIS), the Canadian National Seismic Network (CNSN), as well as data from EarthScope seismic stations, and from the Canadian Northwest Experiment (CANOE) temporary broadband array deployment. This dataset densely samples several regions in our study area and significantly improves the sampling for this area compared to previous precursor studies. Data with common central SS bouncepoints are stacked to enhance precursory phases. Solution discontinuity structure depends on a number of factors, including dominant seismic period, crustal correction, signal-to-noise ratio threshold, and tomography model used for mantle heterogeneity correction. We exclude precursor data predicted to interfere with other seismic phases, such as topside reflections (e.g., s670sS), which have been demonstrated to contaminate final stacks. Solution transition zone thickness is at least 20 km thicker than global average estimates of 242 km along the northwestern portion of the South American subduction complex (Peru, Ecuador, and Columbia); this thickening extends 1000-1500 km to the east beneath the continent, but does not appear to continue south of -20° latitude along the convergent margin. A minimum of 10 km of thickening is imaged to the west of the Scotia

  2. Terahertz spectral signatures of explosive materials and precursors

    Science.gov (United States)

    Ball, Christopher D.; Ronningen, T. J.; Oesterling, Lee C.

    2009-05-01

    Terahertz (THz) spectral signatures have been measured for a variety of explosive materials and precursors. These signatures were measured by THz Time Domain Spectroscopy, using ultrashort pulsed lasers coupled with electro-optic materials to generate and detect THz radiation. Transmission and reflection spectra were measured across a frequency range from 0.2 to 2.5 THz for solid and liquid materials. These spectra are reported in terms of index of refraction and absorption coefficient, both of which can be calculated from transmission or reflection data. The value of THz spectral signatures for the development of future explosives sensing systems is discussed.

  3. Thin films by metal-organic precursor plasma spray

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, Douglas L.; Sailer, Robert A.; Payne, Scott; Leach, James; Molz, Ronald J. [North Dakota State University, Fargo, North Dakota 58108-6050 (United States); Sulzer Metco (United States) Inc., Westbury, New York 11590-2724 (United States)

    2009-07-15

    While most plasma spray routes to coatings utilize solids as the precursor feedstock, metal-organic precursor plasma spray (MOPPS) is an area that the authors have investigated recently as a novel route to thin film materials. Very thin films are possible via MOPPS and the technology offers the possibility of forming graded structures by metering the liquid feed. The current work employs metal-organic compounds that are liquids at standard temperature-pressure conditions. In addition, these complexes contain chemical functionality that allows straightforward thermolytic transformation to targeted phases of interest. Toward that end, aluminum 3,5-heptanedionate (Al(hd){sub 3}), triethylsilane (HSi(C{sub 2}H{sub 5}){sub 3} or HSiEt{sub 3}), and titanium tetrakisdiethylamide (Ti(N(C{sub 2}H{sub 5}){sub 2}){sub 4} or Ti(NEt{sub 2}){sub 4}) were employed as precursors to aluminum oxide, silicon carbide, and titanium nitride, respectively. In all instances, the liquids contain metal-heteroatom bonds envisioned to provide atomic concentrations of the appropriate reagents at the film growth surface, thus promoting phase formation (e.g., Si-C bond in triethylsilane, Ti-N bond in titanium amide, etc.). Films were deposited using a Sulzer Metco TriplexPro-200 plasma spray system under various experimental conditions using design of experiment principles. Film compositions were analyzed by glazing incidence x-ray diffraction and elemental determination by x-ray spectroscopy. MOPPS films from HSiEt{sub 3} showed the formation of SiC phase but Al(hd){sub 3}-derived films were amorphous. The Ti(NEt{sub 2}){sub 4} precursor gave MOPPS films that appear to consist of nanosized splats of TiOCN with spheres of TiO{sub 2} anatase. While all films in this study suffered from poor adhesion, it is anticipated that the use of heated substrates will aid in the formation of dense, adherent films.

  4. The wireless networking system of Earthquake precursor mobile field observation

    Science.gov (United States)

    Wang, C.; Teng, Y.; Wang, X.; Fan, X.; Wang, X.

    2012-12-01

    The mobile field observation network could be real-time, reliably record and transmit large amounts of data, strengthen the physical signal observations in specific regions and specific period, it can improve the monitoring capacity and abnormal tracking capability. According to the features of scatter everywhere, a large number of current earthquake precursor observation measuring points, networking technology is based on wireless broadband accessing McWILL system, the communication system of earthquake precursor mobile field observation would real-time, reliably transmit large amounts of data to the monitoring center from measuring points through the connection about equipment and wireless accessing system, broadband wireless access system and precursor mobile observation management center system, thereby implementing remote instrument monitoring and data transmition. At present, the earthquake precursor field mobile observation network technology has been applied to fluxgate magnetometer array geomagnetic observations of Tianzhu, Xichang,and Xinjiang, it can be real-time monitoring the working status of the observational instruments of large area laid after the last two or three years, large scale field operation. Therefore, it can get geomagnetic field data of the local refinement regions and provide high-quality observational data for impending earthquake tracking forecast. Although, wireless networking technology is very suitable for mobile field observation with the features of simple, flexible networking etc, it also has the phenomenon of packet loss etc when transmitting a large number of observational data due to the wireless relatively weak signal and narrow bandwidth. In view of high sampling rate instruments, this project uses data compression and effectively solves the problem of data transmission packet loss; Control commands, status data and observational data transmission use different priorities and means, which control the packet loss rate within

  5. Beryllium-10 in Australasian tektites - Evidence for a sedimentary precursor

    Science.gov (United States)

    Pal, D. K.; Moniot, R. K.; Kruse, T. H.; Herzog, G. F.; Tuniz, C.

    1982-01-01

    Each of seven Australasian tektites contains about 100 micron atoms of beryllium-10 (half-life, 1.53 million years) per gram. Cosmic-ray bombardment of the australites cannot have produced the measured amounts of beryllium-10 either at the earth's surface or in space. The beryllium-10 contents of these australites are consistent with a sedimentary precursor that adsorbed from precipitation beryllium-10 produced in the atmosphere. The sediments must have spent several thousand years at the earth's surface within a few million years of the tektite-producing event.

  6. A Precursor of Modern Economic Thought: Antoine Laurent de Lavoisier

    Directory of Open Access Journals (Sweden)

    Andreea VASILIU

    2011-02-01

    Full Text Available In the context of development of economic relations, national accounting is a necessity. Building a system of information on gross domestic product, size of national wealth, financial relations and cash flows determine studies on the economic forecast, the distribution and accumulation of national wealth. Efforts in this direction have been numerous and have their roots in the work of Antoine Laurent Lavoisier . He was he who first promulgated the concepts and specific national accounting methods. He was a precursor of modern economic thought.

  7. Precursors of executive function in infants with sickle cell anemia

    OpenAIRE

    Hogan, A. M.; Telfer, P. T.; Kirkham, F J; Haan, M. de

    2013-01-01

    Executive dysfunction occurs in sickle cell anemia, but there are few early data. Infants with sickle cell anemia (n = 14) and controls (n = 14) performed the “A-not-B” and Object Retrieval search tasks, measuring precursors of executive function at 9 and 12 months. Significant group differences were not found. However, for the A-not-B task, 7 of 11 sickle cell anemia infants scored in the lower 2 performance categories at 9 months, but only 1 at 12 months (P = .024); controls obtained scores...

  8. Graphene nanoribbons synthesized from molecular precursor polymerization on Au(110)

    Energy Technology Data Exchange (ETDEWEB)

    Massimi, Lorenzo; Ourdjini, Oualid; Della Pia, Ada; Mariani, Carlo; Betti, Maria Grazia [Dipartimento di Fisica, Università di Roma La Sapienza, Piazzale Aldo Moro 2, I - 00185 Roma (Italy); Cavaliere, Emanuele; Gavioli, Luca [i-LAMP & Dipartimento di Matematica e Fisica, Università Cattolica, 25121 Brescia (Italy)

    2015-06-23

    A spectroscopic study of 10,10-dibromo-9,9 bianthracene (DBBA) molecules deposited on the Au(110) surface is presented, by means of ultraviolet and X-ray photoemission, and X-ray absorption spectroscopy. Through a thermally activated procedure, these molecular precursors polymerize and eventually form graphene nanoribbons (GNRs) with atomically controlled shape and width, very important building blocks for several technological applications. The GNRs observed by scanning tunneling microscopy (STM) appear as short segments on top of the gold surface reconstruction, pointing out the delicate balance among surface diffusion and surface corrugation in their synthesis on the Au(110) surface.

  9. 10 um wavefront spatial filtering first results with chalcogenide fibers

    CERN Document Server

    Bordé, P J; Nguyen, T; Amy-Klein, A; Daussy, C; Raynal, P; Léger, A; Mazé, G; Borde, Pascal; Perrin, Guy; Nguyen, Thanh; Amy-Klein, Anne; Daussy, Christophe; Raynal, Pierre-Ivan; Leger, Alain; Maze, Gwenael

    2003-01-01

    Wavefront cleaning by single-mode fibers has proved to be efficient in optical-infrared interferometry to improve calibration quality. For instance, the FLUOR instrument has demonstrated the capability of fluoride glass single-mode fibers in this respect in the K and L bands. New interferometric instruments developped for the mid-infrared require the same capability for the 8-12 um range. We have initiated a program to develop single-mode fibers in the prospect of the VLTI mid-infrared instrument MIDI and of the ESA/DARWIN and NASA/TPF missions that require excellent wavefront quality. In order to characterize the performances of chalcogenide fibers we are developping, we have set up an experiment to measure the far-field pattern radiated at 10 um. In this paper, we report the first and promising results obtained with this new component.

  10. Resenha da Obra Dom Pedro II: Um Tradutor Imperial

    Directory of Open Access Journals (Sweden)

    Patricia Leonor Martins

    2015-07-01

    Full Text Available Romanelli, S; Soares, G. N.; Souza, R. de.  (Orgs.. Dom Pedro II: Um Tradutor Imperial, Tubarão: Ed. Copiart; Florianópolis: PGET/UFSC, 2013., 260p. A obra recém-publicada, intitulada Dom Pedro II: Um tradutor Imperial apresenta as análises dos manuscritos das traduções realizados pelo segundo Imperador brasileiro para o português das obras As mil e uma noites (do árabe, Hitopadesa (do sânscrito, A Divina comédia (do toscano, La Araucana (do espanhol e Il cinque maggio (do italiano. Escrito e organizado por Noêmia Guimarães Soares, Rosane de Souza e Sergio Romanelli, com participação de Romeu Porto Daros, Adriano Mafra, Ana Maria Sackl e Rosana Schmidt.

  11. Carlos Cruz : um olhar sobre o escândalo

    OpenAIRE

    Diniz, Mafalda

    2012-01-01

    O trabalho apresentado sob o título Carlos Cruz: um olhar sobre o escândalo, aborda o caso Carlos Cruz. Este insere-se no processo Casa Pia e é visto como um escândalo mediático. Atualmente, a palavra “escândalo” aparece com alguma frequência nos mass media. Esta palavra prende-se com a transgressão dos códigos morais que provocam a desaprovação dos outros. Algumas transgressões são pequenas demais para serem consideradas escândalo, enquanto outras podem ser demasiado sérias. O escândal...

  12. Xantelasma: relato de um caso Eyelid xanthelasma: a case report

    Directory of Open Access Journals (Sweden)

    André Henrique Miranda

    2001-04-01

    Full Text Available Os autores relatam um caso raro em paciente do sexo masculino, de 71 anos de idade, com história de surgimento de "carocinho" na pálpebra superior direita há nove anos, que teve aumento importante há um ano. A tomografia computadorizada evidenciou espessamento da musculatura do reto lateral e de partes moles adjacentes. O diagnóstico pela biópsia foi de xantelasma.The authors report a rare case of a 71-year-old male patient with a 9-year history of appearance of a "little node" in the right superior eyelid, which increased significantly in size in the last year. Computed tomography showed thickening of the lateral rectus muscle and adjacent soft tissues. The diagnosis after biopsy was xanthelasma.

  13. Marcuse e Flusser: para iniciar um diálogo

    Directory of Open Access Journals (Sweden)

    Maria Teresa Cardoso de Campos

    2011-04-01

    Full Text Available Herbert Marcuse e Vilém Flusser realizam uma aguda crítica da razão prevalecente na sociedade contemporânea, ao identificar os instrumentos que promovem a manipulação e a programação das consciências, isto é, os mecanismos de controle, na visão de Herbert Marcuse, e os aparelhos que portam programas, de acordo com Vilém Flusser. Pretendemos apresentar esses pontos de contato entre as ideias dos dois filósofos e como a comunicação de massa se insere na discussão de cada um deles. Este trabalho é um início de diálogo entre o pensamento de ambos.

  14. Esquistossomose medular: forma tumoral. Relato de um caso

    Directory of Open Access Journals (Sweden)

    J. Francisco Salomão

    1987-09-01

    Full Text Available Os autores relatam o caso de um jovem procedente de área endêmica e que apresentou quadro de compressão medular por um granuloma esquistos-somótico. A lesão encontrava-se localizada ao nível do cone medular e epicone, sendo parcialmente removida. Discutem as características clínicas e patológicas da mielopatia esquistossomótica, com ênfase especial à forma tumoral da parasitose. Discute-se também a frequência do acometimento medular, admitindo-se ser a doença bem mais frequente do que se supõe. Revisão da literatura pertinente é realizada.

  15. (Lueji, O Nascimento de Um Império)

    OpenAIRE

    Lopes, Isabel Cristina Gonçalves

    2007-01-01

    Dissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Literatura. Partindo do mesmo gosto pela literatura africana e, em particular, pelo romance histórico, esta dissertação incide na análise da obra de Pepetela, Lueji, O Nascimento de Um Império, um romance histórico que ficciona a origem lendária de Angola nas duas narrativas de Lueji e de Lu, visando, simultaneamente, a crítica à ausência de raízes e a importância das mesm...

  16. Lacan e Frege: sobre o conceito de Um

    Directory of Open Access Journals (Sweden)

    Maurício José d’Escragnolle Cardoso

    2010-03-01

    Full Text Available Muitas vezes ignorada, a importância dada por Lacan à obra de Frege se mostra na verdade cada vez mais considerável. Citada pelo psicanalista desde os anos 1950, a importância dessa obra evolui na mesma medida que o ensino lacaniano. Este privilégio é devido não somente à crescente sofisticação da reflexão de Lacan, mas sobretudo a seu esforço em determinar uma questão bastante específica: como isolar a articulação existente entre a estrutura diferencial do significante e a economia pulsional? Este problema encontra sua formulação mais explícita na elaboração lacaniana do conceito de Um, que é justamente realizada através de um diálogo constante com o logicismo fregeano.

  17. POR UM NOVO HORIZONTE PROFISSIONAL DO TURISMÓLOGO

    Directory of Open Access Journals (Sweden)

    Eduardo Yázigi

    2011-12-01

    Full Text Available Resumo – Hoje, a organização do trabalho mostra a necessidade de que o diploma de curso superior posicione um campo operacional bem definido. Em contrapartida, na medida em que o Ministério da Educação oficializa o que seja um curso de Turismo, resultaria incoerente não abonar as especializações do turismólogo enquanto profissão, como sustenta este artigo. O campo de atuação que se abre, entretanto, seria o planejamento territorial urbano, com amplas chances de atuação para o turismólogos como profissionais especializados. Palavras chave – Turismo. Atuação Profissional. Planejamento Urbano.

  18. A economia solidária: Um movimento internacional

    Directory of Open Access Journals (Sweden)

    Jean-Louis Laville

    2012-12-01

    Full Text Available O artigo mostra como em diferentes contextos nacionais e continentais se gerou um movimento de economia solidária. A diversidade de práticas no seio da sociedade civil local e internacional merece ser sublinhada. Esta geração de iniciativas, simultaneamente políticas e econômicas surgidas nas últimas décadas, prolonga e renova a economia social, oferecendo, assim, propostas concretas para uma outra economia, num período de crise capitalista. Como tal, não pode ser ignorada na busca de um modelo económico e de uma acção pública renovada.

  19. Perfluoroalkyl Acids (PFAAs) and Selected Precursors in the Baltic Sea Environment: Do Precursors Play a Role in Food Web Accumulation of PFAAs?

    Science.gov (United States)

    Gebbink, Wouter A; Bignert, Anders; Berger, Urs

    2016-06-21

    The present study examined the presence of perfluoroalkyl acids (PFAAs) and selected precursors in the Baltic Sea abiotic environment and guillemot food web, and investigated the relative importance of precursors in food web accumulation of PFAAs. Sediment, water, zooplankton, herring, sprat, and guillemot eggs were analyzed for perfluoroalkane sulfonic acids (PFSAs; C4,6,8,10) and perfluoroalkyl carboxylic acids (PFCAs; C6-15) along with six perfluoro-octane sulfonic acid (PFOS) precursors and 11 polyfluoroalkyl phosphoric acid diesters (diPAPs). FOSA, FOSAA and its methyl and ethyl derivatives (Me- and EtFOSAA), and 6:2/6:2 diPAP were detected in sediment and water. While FOSA and the three FOSAAs were detected in all biota, a total of nine diPAPs were only detected in zooplankton. Concentrations of PFOS precursors and diPAPs exceeded PFOS and PFCA concentrations, respectively, in zooplankton, but not in fish and guillemot eggs. Although PFOS precursors were present at all trophic levels, they appear to play a minor role in food web accumulation of PFOS based on PFOS precursor/PFOS ratios and PFOS and FOSA isomer patterns. The PFCA pattern in fish could not be explained by the intake pattern based on PFCAs and analyzed precursors, that is, diPAPs. Exposure to additional precursors might therefore be a dominant exposure pathway compared to direct PFCA exposure for fish. PMID:27192404

  20. Methods of making copper selenium precursor compositions with a targeted copper selenide content and precursor compositions and thin films resulting therefrom

    Science.gov (United States)

    Curtis, Calvin J.; Miedaner, Alexander; van Hest, Marinus Franciscus Antonius Maria; Ginley, David S.; Leisch, Jennifer; Taylor, Matthew; Stanbery, Billy J.

    2011-09-20

    Precursor compositions containing copper and selenium suitable for deposition on a substrate to form thin films suitable for semi-conductor applications. Methods of forming the precursor compositions using primary amine solvents and methods of forming the thin films wherein the selection of temperature and duration of heating controls the formation of a targeted species of copper selenide.

  1. Um olhar sensível sobre o Holocausto

    Directory of Open Access Journals (Sweden)

    Leniza Kautz Menda

    2007-10-01

    Full Text Available Na obra de Savyon Liebrecht, a família serve para os sobreviventes como uma espécie de âncora existencial, mesmo quando não satisfaz muitos de suas necessidades emocionais. Este artigo analisa o casamento de alguns sobreviventes do Holocausto como um desejo de auto-preservação e segurança pessoal.

  2. O Estrangeiro – Um ensaio em Psicologia Social

    OpenAIRE

    Alfred Schütz

    2010-01-01

    RESUMO: Este texto é uma tradução de um artigo de Alfred Schütz, The Stranger: Na Essay in Social Psychology, publicado originalmente no The Ameri...

  3. Brazilian environmental sociology: a provisional review Sociologia ambiental brasileira: um levantamento provisório

    Directory of Open Access Journals (Sweden)

    Leila da Costa Ferreira

    2002-06-01

    Full Text Available The article aims firstly at the reconstitution and analysis of history within the scope of international environmental sociology situated in the context of contemporary sociology. It also discusses - from the standpoint of literature (Buttel, Dunlap, Hanning, among others - its theoretical-methodological and institutional aspects as well in order to understand the obstacles encountered to legitimate and consolidate a set of problems which, until recently, were not dealt with by social sciences. Secondly, it analyses the Brazilian case. Environmental sociology in Brazil is strongly influenced by American empirical sociology, the precursor of the institutionalization process for the themes. On the other hand, further analysis of this case is relevant to understand the relationship between the scientific sphere, and the creation of environmental policies and social movements.Primeiramente o artigo busca a reconstituição e análise histórica inerente ao escopo da sociologia ambiental internacional no contexto da sociologia contemporânea. Ele também discute - a partir da literatura (Buttel, Dunlap, Hanning, entre outros - seus aspectos teórico-metodológicos e institucionais de modo a compreender os obstáculos encontrados para se legitimar e consolidar um conjunto de problemas os quais, até recentemente, não eram trabalhados pelas Ciências Sociais. No segundo momento o artigo analisa o caso brasileiro. A sociologia ambiental no Brasil é fortemente influenciada pela sociologia empírica americana, a precursora no processo de institucionalização desses temas. Por outro lado, uma análise posterior sobre esse caso é relevante para se compreender a relação entre a esfera científica, a implementação de políticas ambientais e os movimentos sociais.

  4. Etnografia do ensino médico em um CTI

    Directory of Open Access Journals (Sweden)

    Rachel Aisengart Menezes

    2001-08-01

    Full Text Available Este artigo versa sobre as atividades de ensino e aprendizagem prática em um Centro de Tratamento Intensivo Geral de um hospital público universitário do Rio de Janeiro. A formação profissional do médico não consiste apenas na incorporação de novos conhecimentos, pois é nos estágios práticos que o estudante é forjado como profissional. Em pesquisa etnográfica - centrada no processo de tomada de decisões médicas referentes à vida, sofrimento e morte dos doentes internados no CTI, as atividades de ensino e de aprendizagem revelaram-se de grande importância. A construção de uma identidade profissional médica no estágio em CTI compreende a aquisição de novas formas de ver e descodificar o corpo humano à luz de múltiplos saberes, novos modos de comunicação, como também das formas de gestão das emoções construídas pela equipe. Ao longo deste processo de aprendizagem médica, o estudante deve aprender a se posicionar diante de dilemas éticos, particularmente relevantes em um CTI.

  5. Câncer: filme menor que inventa um povo

    Directory of Open Access Journals (Sweden)

    Sylvia Beatriz Bezerra Furtado

    2014-06-01

    Full Text Available Neste artigo, procuramos trabalhar em torno de duas articulações centrais: o problema do menor e a invenção de um povo. Nos colocamos com as imagens da obra em questão, Câncer (1968-1972, de Glauber Rocha, matéria plástica e sonora que guia o percurso aqui traçado. As potências das imagens como composto sensível capaz de produzir fissuras nas ordenações dos modos de ver, dizer e sentir são elementos que movimentam a análise. Falamos em maneiras de tensionar com os consensos e instaurar outros pensamentos em torno dos possíveis do espaço e do tempo. Como hipótese lançada, a noção de que Câncer seria um filme menor que traria tensões com formas maiores de cinema e com os fatos majoritários, procedimento entendido em suas dimensões políticas. O devir-menor é percorrido como possibilidade de desencadear outras formas de vida, outras maneiras de estar junto e de pensar o comum, para inventar um povo.

  6. Coriocarcinoma manifestando-se inicialmente como um tumor cerebral

    Directory of Open Access Journals (Sweden)

    José Alberto G. da Silva

    1971-09-01

    Full Text Available Os autores descrevem um caso de coriocarcinoma cerebral metastático, removido cirurgicamente, ocorrendo numa paciente de 19 anos e localizado na porção posterior do lobo frontal esquerdo. Um estudo retrospectivo da paciente revelou apenas discreta perda sangüínea pelos genitais, iniciada algumas semanas após o delivramento de uma criança normal, ocorrido quatro meses antes. O exame colpocitológico da secreção cérvico-vaginal revelou uma classe V de Papanicolau (positivo para células neoplásicas malignas, tendo ulteriormente a paciente sido submetida à histerectomia total com anexectomia bilateral. Um pequeno tumor de aspecto hemorrágico-necrótico foi encontrado na cavidade uterina, tendo o exame histológico mostrado tratar-se de coriocarcinoma. Os autores tecem considerações clínico-patológicas sobre o coriocarcinoma. com especial referência às lesões metastáticas cerebrais.

  7. Silicone Resin Applications for Ceramic Precursors and Composites

    Directory of Open Access Journals (Sweden)

    Masaki Narisawa

    2010-06-01

    Full Text Available This article reviews the applications of silicone resins as ceramic precursors. The historical background of silicone synthesis chemistry is introduced to explain the production costs and supply availability of various silicones. Thermal degradation processes of silicones are classified in terms of the main chain structure and cyclic oligomer expulsion process, which determine the resulting ceramic yield and the chemical composition. The high temperature decomposition of Si-O-C beyond 1,400 °C in an inert atmosphere and formation of a protective silica layer on material surfaces beyond 1,200 °C in an oxidative atmosphere are discussed from the viewpoints of the wide chemical composition of the Si-O-C materials. Applications of the resins for binding agents, as starting materials for porous ceramics, matrix sources with impregnation, fiber spinning and ceramic adhesions are introduced. The recent development of the process of filler or cross-linking agent additions to resin compounds is also introduced. Such resin compounds are useful for obtaining thick coatings, MEMS parts and bulk ceramics, which are difficult to obtain by pyrolysis of simple organometallic precursors without additives.

  8. Effect of capacitive deionization on disinfection by-product precursors.

    Science.gov (United States)

    Liu, Danyang; Wang, Xiaomao; Xie, Yuefeng F; Tang, Hao L

    2016-10-15

    Formation of brominated disinfection by-products (DBPs) from bromide and natural organic matter upon chlorination imposes health risks to drinking water users. In this study, capacitive deionization (CDI) was evaluated as a potential process for DBP precursor removal. Synthetic humic acid and bromide containing saline water was used as model water prior to CDI treatment. Batch experiments were conducted at cell voltages of 0.6-, 0.9-, and 1.2V to study the influence of CDI on the ratio of bromide and dissolved organic carbon, bromine substitution factor, and DBP formation potential (FP). Results showed beneficial aspects of CDI on reducing the levels of these parameters. A maximum DBPFP removal from 1510 to 1160μg/L was observed at the cell voltage of 0.6V. For the removed DBPFP, electro-adsorption played a greater role than physical adsorption. However, it is also noted that there could be electrochemical oxidations that led to reduction of humic content and formation of new dichloroacetic acid precursors at high cell voltages. Because of the potential of CDI on reducing health risks from the formation of less brominated DBPs upon subsequent chlorination, it can be considered as a potential technology for DBP control in drinking water treatment. PMID:27285792

  9. A common precursor to two major crab neurosecretory peptides.

    Science.gov (United States)

    Stuenkel, E L

    1986-01-01

    The biosynthesis of proteins by the X-organ sinus gland (XOSG) neurosecretory system of the crab, Cardisoma carnifex was studied using the pulse-chase technique. Analysis of radioactive proteins following 2D-PAGE showed that during pulse incubations of less than or equal to 30 min a single predominant 14Kd prohormone was synthesized. With chase less than or equal to 3 hr the primary 14Kd protein was found to undergo differential and/or multiple post-translational modifications prior to its proteolytic cleavage. Increasing the chase to greater than 3 hr showed a shift in labeling from the 14Kd forms to 3 separate 6Kd proteins. Two of the 6Kd proteins were identified as crustacean hyperglycemic peptides (CHH). Similarity in protein labeling using [3H]leucine and [35S]cysteine suggest a second major peptide group, the H peptide, known to lack cysteine, is also contained within the 14Kd precursor. Peptide mapping of the 14Kd proteins and of unlabeled CHH and peptide H provide substantive evidence for this biosynthetic scheme. Thus, both the CHH and H peptide groups, which together constitute greater than 90% of the XOSG peptide content, in this species, arise from a common 14Kd precursor molecule.

  10. An Accident Precursor Analysis Process Tailored for NASA Space Systems

    Science.gov (United States)

    Groen, Frank; Stamatelatos, Michael; Dezfuli, Homayoon; Maggio, Gaspare

    2010-01-01

    Accident Precursor Analysis (APA) serves as the bridge between existing risk modeling activities, which are often based on historical or generic failure statistics, and system anomalies, which provide crucial information about the failure mechanisms that are actually operative in the system and which may differ in frequency or type from those in the various models. These discrepancies between the models (perceived risk) and the system (actual risk) provide the leading indication of an underappreciated risk. This paper presents an APA process developed specifically for NASA Earth-to-Orbit space systems. The purpose of the process is to identify and characterize potential sources of system risk as evidenced by anomalous events which, although not necessarily presenting an immediate safety impact, may indicate that an unknown or insufficiently understood risk-significant condition exists in the system. Such anomalous events are considered accident precursors because they signal the potential for severe consequences that may occur in the future, due to causes that are discernible from their occurrence today. Their early identification allows them to be integrated into the overall system risk model used to intbrm decisions relating to safety.

  11. Follicular dendritic cells emerge from ubiquitous perivascular precursors.

    Science.gov (United States)

    Krautler, Nike Julia; Kana, Veronika; Kranich, Jan; Tian, Yinghua; Perera, Dushan; Lemm, Doreen; Schwarz, Petra; Armulik, Annika; Browning, Jeffrey L; Tallquist, Michelle; Buch, Thorsten; Oliveira-Martins, José B; Zhu, Caihong; Hermann, Mario; Wagner, Ulrich; Brink, Robert; Heikenwalder, Mathias; Aguzzi, Adriano

    2012-07-01

    The differentiation of follicular dendritic cells (FDC) is essential to the remarkable microanatomic plasticity of lymphoid follicles. Here we show that FDC arise from ubiquitous perivascular precursors (preFDC) expressing platelet-derived growth factor receptor β (PDGFRβ). PDGFRβ-Cre-driven reporter gene recombination resulted in FDC labeling, whereas conditional ablation of PDGFRβ(+)-derived cells abolished FDC, indicating that FDC originate from PDGFRβ(+) cells. Lymphotoxin-α-overexpressing prion protein (PrP)(+) kidneys developed PrP(+) FDC after transplantation into PrP(-) mice, confirming that preFDC exist outside lymphoid organs. Adipose tissue-derived PDGFRβ(+) stromal-vascular cells responded to FDC maturation factors and, when transplanted into lymphotoxin β receptor (LTβR)(-) kidney capsules, differentiated into Mfge8(+)CD21/35(+)FcγRIIβ(+)PrP(+) FDC capable of trapping immune complexes and recruiting B cells. Spleens of lymphocyte-deficient mice contained perivascular PDGFRβ(+) FDC precursors whose expansion required both lymphoid tissue inducer (LTi) cells and lymphotoxin. The ubiquity of preFDC and their strategic location at blood vessels may explain the de novo generation of organized lymphoid tissue at sites of lymphocytic inflammation. PMID:22770220

  12. Superior Thermal Barrier Coatings Using Solution Precursor Plasma Spray

    Science.gov (United States)

    Jordan, E. H.; Xie, L.; Gell, M.; Padture, N. P.; Cetegen, B.; Ozturk, A.; Ma, X.; Roth, J.; Xiao, T. D.; Bryant, P. E. C.

    2004-03-01

    A novel process, solution precursor plasma spray (SPPS), is presented for depositing thermal barrier coatings (TBCs), in which aqueous chemical precursors are injected into a standard direct current plasma spray system. The resulting coatings microstructure has three unique features: (1) ultra fine splats (1 µm), (2) nanometer and micron-sized interconnected porosity, and (3) closely spaced, through-thickness cracks. Coatings over 3 mm thick can be readily deposited using the SPPS process. Coating durability is excellent, with SPPS coatings showing, in furnace cycling tests, 2.5 times the spallation life of air plasma coatings (APS) and 1.5 times the life of electron beam physical vapor deposited (EB-PVD) coatings. The conductivity of SPPS coatings is lower than EB-PVD coatings and higher than the best APS coatings. Manufacturing cost is expected to be similar to APS coatings and much lower than EB-PVD coatings. The SPPS deposition process includes droplet break-up and material arriving at the deposition surface in various physical states ranging from aqueous solution, gel phase, to fully-molten ceramic. The relation between the arrival state of the material and the microstructure is described.

  13. Neural precursors derived from human embryonic stem cells

    Institute of Scientific and Technical Information of China (English)

    Peng Hongmei; Chen Gui'an

    2005-01-01

    Human embryonic stem (hES) cells provide a promising supply of specific cell types for transplantation therapy. We presented here the method to induce differentiation of purified neural precursors from hES cells, hES cells (Line PKU-1 and Line PKU-2) were cultured in suspension in bacteriological Petri dishes, which differentiated into cystic embryoid bodies (EBs).The EBs were then cultured in N2 medium containing bFGF in poly- L-lysine-coated tissue culture dishes for two weeks. The central, small cells with 2-3 short processes of the spreading outgrowth were isolated mechanically and replated. The resulting neurospheres were cultured in suspension for 10 days, then dissociated into single cell suspension with a Pasteur pipette and plated. Cells grew vigorously in an attached way and were passed every 4-5 days. Almost all the cells were proved nestin positive by immunostaining. Following withdrawal of bFGF, they differentiated into neurons expressing β-tubulin isotypeⅢ, GABA, serotonin and synaptophysin.Through induction of PDGF-AA, they differentiated into astrocytes expressing GFAP and oligodendrocytes expressing O4. The results showed that hES cells can differentiate into typical neural precursors expressing the specific marker nestin and capable of generating all three cell types of the central nervous system (CNS) in vitro.

  14. Advanced accident sequence precursor analysis level 2 models

    Energy Technology Data Exchange (ETDEWEB)

    Galyean, W.J.; Brownson, D.A.; Rempe, J.L. [and others

    1996-03-01

    The U.S. Nuclear Regulatory Commission Accident Sequence Precursor program pursues the ultimate objective of performing risk significant evaluations on operational events (precursors) occurring in commercial nuclear power plants. To achieve this objective, the Office of Nuclear Regulatory Research is supporting the development of simple probabilistic risk assessment models for all commercial nuclear power plants (NPP) in the U.S. Presently, only simple Level 1 plant models have been developed which estimate core damage frequencies. In order to provide a true risk perspective, the consequences associated with postulated core damage accidents also need to be considered. With the objective of performing risk evaluations in an integrated and consistent manner, a linked event tree approach which propagates the front end results to back end was developed. This approach utilizes simple plant models that analyze the response of the NPP containment structure in the context of a core damage accident, estimate the magnitude and timing of a radioactive release to the environment, and calculate the consequences for a given release. Detailed models and results from previous studies, such as the NUREG-1150 study, are used to quantify these simple models. These simple models are then linked to the existing Level 1 models, and are evaluated using the SAPHIRE code. To demonstrate the approach, prototypic models have been developed for a boiling water reactor, Peach Bottom, and a pressurized water reactor, Zion.

  15. High-quality CdTe films from nanoparticle precursors

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, D.L.; Pehnt, M.; Urgiles, E. [National Renewable Energy Lab., Golden, CO (United States)] [and others

    1996-05-01

    In this paper the authors demonstrate that nanoparticulate precursors coupled with spray deposition offers an attractive route into electronic materials with improved smoothness, density, and lower processing temperatures. Employing a metathesis approach, cadmium iodide was reacted with sodium telluride in methanol solvent, resulting in the formation of soluble NaI and insoluble CdTe nanoparticles. After appropriate chemical workup, methanol-capped CdTe colloids were isolated. CdTe thin film formation was achieved by spray depositing the nanoparticle colloids (25-75 {Angstrom} diameter) onto substrates at elevated temperatures (T = 280-440{degrees}C) with no further thermal treatment. These films were characterized by x-ray diffraction (XRD), x-ray photoelectron spectroscopy (XPS), and atomic force microscopy (AFM). Cubic CdTe phase formation was observed by XRD, with a contaminant oxide phase also detected. XPS analysis showed that CdTe films produced by this one-step method contained no Na or C and substantial O. AFM gave CdTe grain sizes of {approx}0.1-0.3 {mu}m for film sprayed at 400{degrees}C. A layer-by-layer film growth mechanism proposed for the one-step spray deposition of nanoparticle precursors will be discussed.

  16. Thermodynamic equilibrium calculation on preparation of copper oxalate precursor powder

    Institute of Scientific and Technical Information of China (English)

    FAN You-qi; ZHANG Chuan-fu; ZHAN Jing; WU Jian-hui

    2008-01-01

    According to the principles of simultaneous equilibrium and mass balance, a series of thermodynamic equilibrium equations of Cu2+ -C2O2-4 -NH3-NH4+-H2O system at ambient temperature were deduced theoretically and the logarithm concentration versus pH value (lg[Cu2+]T-pH) diagrams at different solution compositions were drawn. The results show that when pH is below 5.0, copper ion reacts with C2O42- directly and the morphology of copper precursor powder is of pie-shape; when pH is above 5.0, copper ion coordinates with ammonia, and the precipitation proceeds slowly accompanying with the release of copper ions from the multi-coordinated Cu(NH3)n2+ (n =1, 2, …, 5) and the morphologies of copper precursor powder are respectively of rod aggregation shape (when 5.0<pH<8.0) and of rod-shape (when pH>8.0). Some experiments were performed to confirm the relation between the total concentration of copper ion and pH value. It is shown that the thermodynamic mathematical model is correct and the calculated values are basically accurate.

  17. Lacustrine biomass: An significant precursor of high wax oil

    Institute of Scientific and Technical Information of China (English)

    HUANG Haiping; ZHENG Yabin; ZHANG Zhanwen; LI Jinyou

    2003-01-01

    Although a variety of precursors have been proposed for the formation of high molecular weight hydrocarbons (HMWHCs) in crude oil, their precise origin remains elusive. Quantitative studies of macrocrystalline wax and microcrystalline wax content of source rock extracts from the Damintun depression, Liaohe Basin, a typical high wax producing area, coupled with microscopical maceral composition studies and pyrolysis-GC analysis indicate that oil shale enriched in lacustrine biomass makes a primary contribution to wax in oil. The main precursors of high wax oil are lacustrine alginites and their amorphous matrix, which are highly aliphatic in nature and have high generative potential for HMWHCs. Wax generation efficiency could be affected by organic material abundance and maturity. The high abundance and low maturity of organic material are favorite for the formation of high quantity of wax, which declines with decreasing organic abundance and increasing thermal maturity. This suggests that wax is derived from organic-rich lacustrine biomass at early stages of maturation (RO = 0.4%-0.7%). Although the contribution of high plant cuticular wax and sporopollen cannot be ruled out, lacustrine biomass is more important in the formation of high wax oil.

  18. Processing Pisum sativum seed storage protein precursors in vitro

    Institute of Scientific and Technical Information of China (English)

    YANGLIJUN; CDOMONEY; 等

    1990-01-01

    The profile of polypeptides separated by SDS-PAGE from seed of major crop species such as pea(Pisum sativum) is complex,resulting from cleavage (processing) of precursors expressed from multiple copies of genes encoding vicilin and legumin,the major storage globulins.Translation in vitro of mRNAs hybridselected from mid-maturation pea seed RNAs by defined vicilin and legumin cDNA clones provided precursor molecules that were cleaved in vitro by a cell-free protease extract obtained from similar stage seed;the derived polypeptides were of comparable sizes to those observed in vivo.The feasibility of transcribing mRNA in vitro from a cDNA clone and cleavage in vitro of the derived translation products was established for a legumin clone,providing a method for determining polypeptide products of an expressed sequence.This approach will also be useful for characterising cleavage site requirements since modifications an readily be introduced at the DNA level.

  19. AMYPdb: A database dedicated to amyloid precursor proteins

    Directory of Open Access Journals (Sweden)

    Delamarche Christian

    2008-06-01

    Full Text Available Abstract Background Misfolding and aggregation of proteins into ordered fibrillar structures is associated with a number of severe pathologies, including Alzheimer's disease, prion diseases, and type II diabetes. The rapid accumulation of knowledge about the sequences and structures of these proteins allows using of in silico methods to investigate the molecular mechanisms of their abnormal conformational changes and assembly. However, such an approach requires the collection of accurate data, which are inconveniently dispersed among several generalist databases. Results We therefore created a free online knowledge database (AMYPdb dedicated to amyloid precursor proteins and we have performed large scale sequence analysis of the included data. Currently, AMYPdb integrates data on 31 families, including 1,705 proteins from nearly 600 organisms. It displays links to more than 2,300 bibliographic references and 1,200 3D-structures. A Wiki system is available to insert data into the database, providing a sharing and collaboration environment. We generated and analyzed 3,621 amino acid sequence patterns, reporting highly specific patterns for each amyloid family, along with patterns likely to be involved in protein misfolding and aggregation. Conclusion AMYPdb is a comprehensive online database aiming at the centralization of bioinformatic data regarding all amyloid proteins and their precursors. Our sequence pattern discovery and analysis approach unveiled protein regions of significant interest. AMYPdb is freely accessible 1.

  20. Preparation of plutonium-bearing ceramics via mechanically activated precursor

    Science.gov (United States)

    Chizhevskaya, S. V.; Stefanovsky, S. V.

    2000-07-01

    The problem of excess weapons plutonium disposition is suggested to be solved by means of its incorporation in stable ceramics with high chemical durability and radiation resistivity. The most promising host phases for plutonium as well as uranium and neutron poisons (gadolinium, hafnium) are zirconolite, pyrochlore, zircon, zirconia [1,2], and murataite [3]. Their production requires high temperatures and a fine-grained homogeneous precursor to reach final waste form with high quality and low leachability. Currently various routes to homogeneous products preparation such as sol-gel technology, wet-milling, and grinding in a ball or planetary mill are used. The best result demonstrates sol-gel technology but this route is very complicated. An alternative technology for preparation of ceramic precursors is the treatment of the oxide batch with high mechanical energy [4]. Such a treatment produces combination of mechanical (fine milling with formation of various defects, homogenization) and chemical (split bonds with formation of active centers—free radicals, ion-radicals, etc.) effects resulting in higher reactivity of the activated batch.

  1. Radial velocities and metallicities from infrared Ca II triplet spectroscopy of open clusters II. Berkeley 23, King 1, NGC 559, NGC 6603 and NGC 7245

    CERN Document Server

    Carrera, R; Ospina, N; Balaguer-Nuñez, L; Jordi, C; Monteagudo, L

    2015-01-01

    Context: Open clusters are key to studying the formation and evolution of the Galactic disc. However, there is a deficiency of radial velocity and chemical abundance determinations for open clusters in the literature. Aims: We intend to increase the number of determinations of radial velocities and metallicities from spectroscopy for open clusters. Methods: We acquired medium-resolution spectra (R~8000) in the infrared region Ca II triplet lines (~8500 AA) for several stars in five open clusters with the long-slit IDS spectrograph on the 2.5~m Isaac Newton Telescope (Roque de los Muchachos Observatory, Spain). Radial velocities were obtained by cross-correlation fitting techniques. The relationships available in the literature between the strength of infrared Ca II lines and metallicity were also used to derive the metallicity for each cluster. Results: We obtain = 48.6+/-3.4, -58.4+/-6.8, 26.0+/-4.3 and -65.3+/-3.2 km s-1 for Berkeley 23, NGC 559, NGC 6603 and NGC 7245, respectively. We found [Fe/H] =-0.25+...

  2. Plutonium working group report on environmental, safety and health vulnerabilities associated with the department's plutonium storage. Volume II, part 11: Lawrence Berkeley Laboratory working group assessment team report

    International Nuclear Information System (INIS)

    President Clinton has directed an Interagency Working Group to initiate a comprehensive review of long-term options for the disposition of surplus plutonium. As part of this initiative, Secretary of Energy, Hazel O'Leary, has directed that a Department of Energy project be initiated to develop options and recommendations for the safe storage of these materials in the interim. A step in the process is a plutonium vulnerability assessment of facilities throughout the Department. The Plutonium Vulnerability Working Group was formed to produce the Project and Assessment Plans, to manage the assessments and to produce a final report for the Secretary by September 30, 1994. The plans established the approach and methodology for the assessment. The Project Plan specifies a Working Group Assessment Team (WGAT) to examine each of the twelve DOE sites with significant holdings of plutonium. The Assessment Plan describes the methodology that the Site Assessment Team (SAT) used to report on the plutonium holdings for each specific site.This report provides results of the assessment of the Lawrence Berkeley Laboratory

  3. The little-studied cluster Berkeley 90. I. LS III +46 11: a very massive O3.5 If* + O3.5 If* binary

    CERN Document Server

    Apellániz, J Maíz; Barbá, R H; Walborn, N R; Pellerin, A; Simón-Díaz, S; Sota, A; Marco, A; Alonso-Santiago, J; Bermudez, J Sanchez; Gamen, R C; Lorenzo, J

    2015-01-01

    Context: It appears that most (if not all) massive stars are born in multiple systems. At the same time, the most massive binaries are hard to find due to their low numbers throughout the Galaxy and the implied large distances and extinctions. AIMS: We want to study: [a] LS III +46 11, identified in this paper as a very massive binary; [b] another nearby massive system, LS III +46 12; and [c] the surrounding stellar cluster, Berkeley 90. Methods: Most of the data used in this paper are multi-epoch high-S/N optical spectra though we also use Lucky Imaging and archival photometry. The spectra are reduced with devoted pipelines and processed with our own software, such as a spectroscopic-orbit code, CHORIZOS, and MGB. Results: LS III +46 11 is identified as a new very-early-O-type spectroscopic binary [O3.5 If* + O3.5 If*] and LS III +46 12 as another early O-type system [O4.5 V((f))]. We measure a 97.2-day period for LS III +46 12 and derive minimum masses of 38.80$\\pm$0.83 M_Sol and 35.60$\\pm$0.77 M_Sol for it...

  4. Advancing Space Sciences through Undergraduate Research Experiences at UC Berkeley's Space Sciences Laboratory - a novel approach to undergraduate internships for first generation community college students

    Science.gov (United States)

    Raftery, C. L.; Davis, H. B.; Peticolas, L. M.; Paglierani, R.

    2015-12-01

    The Space Sciences Laboratory at UC Berkeley launched an NSF-funded Research Experience for Undergraduates (REU) program in the summer of 2015. The "Advancing Space Sciences through Undergraduate Research Experiences" (ASSURE) program recruited heavily from local community colleges and universities, and provided a multi-tiered mentorship program for students in the fields of space science and engineering. The program was focussed on providing a supportive environment for 2nd and 3rd year undergraduates, many of whom were first generation and underrepresented students. This model provides three levels of mentorship support for the participating interns: 1) the primary research advisor provides academic and professional support. 2) The program coordinator, who meets with the interns multiple times per week, provides personal support and helps the interns to assimilate into the highly competitive environment of the research laboratory. 3) Returning undergraduate interns provided peer support and guidance to the new cohort of students. The impacts of this program on the first generation students and the research mentors, as well as the lessons learned will be discussed.

  5. Protótipo laboratorial de um microscópio de varrimento tusando um sensor linear: avaliação da sua resposta axial

    OpenAIRE

    Barata, António Júlio de Almeida Proença

    2008-01-01

    O objectivo do presente trabalho consistiu em criar um sistema laboratorial que envolva diferentes áreas como a electrónica, óptica, processamento de sinal e software para tornar possível o uso de um sensor linear como detector num microscópio óptico de varrimento (SOM - Scanning Optical Microscope) avaliando a sua confocalidade. Foi construído um protótipo de baixo custo de um sistema SOM com configuração em reflexão epi-iluminada e a utilização do varrimento da plataforma do ...

  6. Methods of forming single source precursors, methods of forming polymeric single source precursors, and single source precursors formed by such methods

    Energy Technology Data Exchange (ETDEWEB)

    Fox, Robert V.; Rodriguez, Rene G.; Pak, Joshua J.; Sun, Chivin; Margulieux, Kelsey R.; Holland, Andrew W.

    2016-04-19

    Methods of forming single source precursors (SSPs) include forming intermediate products having the empirical formula 1/2{L.sub.2N(.mu.-X).sub.2M'X.sub.2}.sub.2, and reacting MER with the intermediate products to form SSPs of the formula L.sub.2N(.mu.-ER).sub.2M'(ER).sub.2, wherein L is a Lewis base, M is a Group IA atom, N is a Group IB atom, M' is a Group IIIB atom, each E is a Group VIB atom, each X is a Group VIIA atom or a nitrate group, and each R group is an alkyl, aryl, vinyl, (per)fluoro alkyl, (per)fluoro aryl, silane, or carbamato group. Methods of forming polymeric or copolymeric SSPs include reacting at least one of HE.sup.1R.sup.1E.sup.1H and MER with one or more substances having the empirical formula L.sub.2N(.mu.-ER).sub.2M'(ER).sub.2 or L.sub.2N(.mu.-X).sub.2M'(X).sub.2 to form a polymeric or copolymeric SSP. New SSPs and intermediate products are formed by such methods.

  7. Plutonium working group report on environmental, safety and health vulnerabilities associated with the department's plutonium storage. Volume II, Appendix B, Part 11: Lawrence Berkeley Laboratory site assessment team report

    International Nuclear Information System (INIS)

    The Lawrence Berkeley Laboratory was founded in 1931 on the Berkeley campus of the University of California. The laboratory evolved from accelerator development and related nuclear physics programs to include energy production, atomic imaging, research medicine, and life sciences. The LBL research with actinide elements, including plutonium, focuses principally to develop methods to dispose of nuclear wastes. Also, LBL uses sources of plutonium to calibrate neutron detectors used at the laboratory. All radiological work at LBL is governed by Publication 3000. In accordance with the directive of Energy Secretary O'Leary open-quote Department of Energy Plutonium ES ampersand H Vulnerability Assessment: Project Plan,close-quote April 25, 19941. Sandia National Laboratories/New Mexico has conducted a site assessment of the SNL/NM site's plutonium environment, safety and health (ES ampersand H) vulnerabilities associated with plutonium and other transuranic material. The results are presented in this report

  8. Instellar Exploration: Propulsion Options for Precursors and Beyond

    Science.gov (United States)

    Johnson, Charles Les; Leifer, Stephanie

    1999-01-01

    NASA is considering a mission to explore near-interstellar space early in the next decade as the first step toward a vigorous interstellar exploration program. A key enabling technology for such an ambitious science and exploration effort is the development of propulsion systems capable of providing fast trip times; mission duration should not exceed the professional lifetime of the investigative team. Advanced propulsion technologies that might support an interstellar precursor mission early in the next century include some combination of solar sails, nuclear electric propulsion systems, and aerogravity assists. Follow-on missions to far beyond the heliopause will require the development of propulsion technologies that are only at the conceptual stage today. These include 1) matter-antimatter annihilation, 2) beamed-energy sails, and 3) fusion systems. For years, the scientific community has been interested in the development of solar sail technology to support exploration of the inner and outer planets. Progress in thin-film technology and the development of technologies that may enable the remote assembly of large sails in space are only now maturing to the point where ambitious interstellar precursor missions can be considered. Electric propulsion is now being demonstrated for planetary exploration by the Deep Space 1 mission. The primary issues for it's adaptation to interstellar precursor applications include the nuclear reactor that would be required and the engine lifetime. For further term interstellar missions, matter-antimatter annihilation propulsion system concepts have the highest energy density of any propulsion systems using onboard propellants. However, there are numerous challenges to production and storage of antimatter that must be overcome before it can be seriously considered for interstellar flight. Off-board energy systems (laser sails) are candidates for long-distance interstellar flight but development of component technologies and

  9. The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisC.

    Directory of Open Access Journals (Sweden)

    Rustem Khusainov

    Full Text Available Precursor nisin is a model posttranslationally modified precursor lantibiotic that can be structurally divided into a leader peptide sequence and a modifiable core peptide part. The nisin core peptide clearly plays an important role in the precursor nisin-nisin modification enzymes interactions, since it has previously been shown that the construct containing only the nisin leader sequence is not sufficient to pull-down the nisin modification enzymes NisB and NisC. Serines and threonines in the core peptide part are the residues that NisB specifically dehydrates, and cysteines are the residues that NisC stereospecifically couples to the dehydrated amino acids. Here, we demonstrate that increasing the number of negatively charged residues in the core peptide part of precursor nisin, which are absent in wild-type nisin, does not abolish binding of precursor nisin to the modification enzymes NisB and NisC, but dramatically decreases the antimicrobial potency of these nisin mutants. An unnatural precursor nisin variant lacking all serines and threonines in the core peptide part and an unnatural precursor nisin variant lacking all cysteines in the core peptide part still bind the nisin modification enzymes NisB and NisC, suggesting that these residues are not essential for direct interactions with the nisin modification enzymes NisB and NisC. These results are important for lantibiotic engineering studies.

  10. Superhydrophobic Ceramic Coatings by Solution Precursor Plasma Spray

    Science.gov (United States)

    Cai, Yuxuan

    Superhydrophobic surfaces exhibit superior water repellent properties, and they have remarkable potential to improve current energy infrastructure. Substantial research has been performed on the production of superhydrophobic coatings. However, superhydrophobic coatings have not yet been adopted in many industries where potential applications exist due to the limited durability of the coating materials and the complex and costly fabrication processes. Here presented a novel coating technique to manufacture ceramic superhydrophobic coatings rapidly and economically. A rare earth oxide (REO) was selected as the coating material due to its hydrophobic nature and strong mechanical properties, and deposited on stainless steel substrates by solution precursor plasma spray (SPPS). The as-sprayed coating demonstrated a hierarchically structured coating topography, which closely resembles superhydrophobic surfaces in nature. Compared to smooth REO surfaces, the SPPS superhydrophobic coating improved the water contact angle by as much as 65° after vacuum treatment at 1 Pa for 48 hours.

  11. Bioexcimers as Precursors of Charge Transfer and Reactivity in Photobiology

    Science.gov (United States)

    Serrano-Andrés, Luis; Merchán, Manuela; Roca-Sanjuán, Daniel; Olaso-González, Gloria; Rubio, Mercedes

    2007-11-01

    Accurate CASPT2//CASSCF calculations show that π-stacked interactions in different biochromophores such as DNA nucleobases or porphyrin-quinone pairs yield excimer-like situations which behave as precursors of processes like charge transfer or photoreactivity. Examples are the transfer of charge between a reduced pheophytin and an accepting quinone molecule, process that trigger the sequence of electron transfer phenomena in photosynthetic photosystem II, the electron transfer between adjacent DNA nucleobases in a strand of oligonucleotides, and the photodimerization taking place in cytosine pairs leading to cyclobutanecytosine mutants. These processes take place through nonadiabatic photochemical mechanisms whose evolution is determined by the presence and accessibility of conical intersections and other surface crossings between different electronic states.

  12. A METHOD DEVELOPED FOR PREDICTING POTENTIAL PRECURSORS OF EARTHQUAKES

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper describes the methodology used to eliminate environmental effects to a time series of short distance(24 m) leveling across a geological fault in order to detect potential precursors of earthquakes from the residual time series. First, linear trends and periodic signals are removed from the observations with the help of a recursive least squares method. Then, a controlled autoregression model is used to predict the enviromnental contribution due to precipitation and evaporation. The difference between the leveling data andthese predictions are considered to be due to endogenic crustal processes. Applying this methodology to leveling data of approximately 13 years at Niukouyu crustal deformation station near Beijing reveals an anomalous deformation before the Tangshan earthquake (M7.8),which has its epicenter about 180 km from the survey site. However, in the time period considered, another anomaly occurred which cannot be related directly to a seismic event.

  13. Solar cycle prediction using precursors and flux transport models

    CERN Document Server

    Cameron, R

    2006-01-01

    We study the origin of the predictive skill of some methods to forecast the strength of solar activity cycles. A simple flux transport model for the azimuthally averaged radial magnetic field at the solar surface is used, which contains a source term describing the emergence of new flux based on observational sunspot data. We consider the magnetic flux diffusing over the equator as a predictor, since this quantity is directly related to the global dipole field from which a Babcock-Leighton dynamo generates the toroidal field for the next activity cycle. If the source is represented schematically by a narrow activity belt drifting with constant speed over a fixed range of latitudes between activity minima, our predictor shows considerable predictive skill with correlation coefficients up to 0.95 for past cycles. However, the predictive skill is completely lost when the actually observed emergence latitudes are used. This result originates from the fact that the precursor amplitude is determined by the sunspot ...

  14. Aluminum borate nanowires from the pyrolysis of polyaminoborane precursors.

    Science.gov (United States)

    Du, Van An; Jurca, Titel; Whittell, George R; Manners, Ian

    2016-01-21

    Polyaminoboranes [N(R)H-BH2]n (1: R = H, 2: R = Me) were pyrolyzed on a range of substrates: silicon, metal foils (stainless steel, nickel, and rhodium), and sapphire wafers, as well as on Al2O3 and AlN powders. The pyrolysis of 2 on a Si-wafer resulted in porous nanostructures containing hexagonal-boron nitride (h-BN). In the case of 1 or H3N·BH3 as precursor, using rhodium foil as substrate afforded amorphous B and N-containing nanostructures, and polydisperse spherical nanoparticles, respectively. Switching the substrate to sapphire wafers, as well as to Al2O3 or AlN powders, resulted in formation of crystalline Al5BO9 nanostructures (nanowires, nanotubes, and nanoribbons). For sapphire wafers, the size of the resulting nanowires was influenced by modifying the surface defect density. PMID:26649782

  15. Are saponins and sapogenins precursors of prednisolone? Preliminary results

    Directory of Open Access Journals (Sweden)

    Giuseppe Federico Labella

    2015-11-01

    Full Text Available The transformation of cortisol into prednisolone in cattle faeces was demonstrated and provided by literature, given the structural similarity of prednisolone with cortisol. In this study, we evaluated a possible neo-formation of prednisolone, as results of a faecal or environmental contamination. A saponine, α-solanine, and a sapogenin, diosgenin, were selected as possible precursors. A simple method without extraction was applied. The analyses were performed by HPLC–MSn to evaluate the possible transformations. The results showed that prednisolone was detected in the faecal suspension spiked with diosgenin at t= 8h, while cortisol was also detected at t = 24h in the sample of faeces spiked with α-solanine. In the feed and in the control samples, no transformations were observed.

  16. Amyloid precursor protein is trafficked and secreted via synaptic vesicles.

    Directory of Open Access Journals (Sweden)

    Teja W Groemer

    Full Text Available A large body of evidence has implicated amyloid precursor protein (APP and its proteolytic derivatives as key players in the physiological context of neuronal synaptogenesis and synapse maintenance, as well as in the pathology of Alzheimer's Disease (AD. Although APP processing and release are known to occur in response to neuronal stimulation, the exact mechanism by which APP reaches the neuronal surface is unclear. We now demonstrate that a small but relevant number of synaptic vesicles contain APP, which can be released during neuronal activity, and most likely represent the major exocytic pathway of APP. This novel finding leads us to propose a revised model of presynaptic APP trafficking that reconciles existing knowledge on APP with our present understanding of vesicular release and recycling.

  17. NASAs Evolvable Mars Campaign: Mars Moons Robotic Precursor

    Science.gov (United States)

    Gernhardt, Michael L.; Abercromby, Andrew F. J.; Abell, Paul A.; Love, Stanley G.; Lee, David E.; Chappell, Steven P.; Howe, A. Scott; Friedensen, Victoria

    2015-01-01

    Human exploration missions to the moons of Mars are being considered within NASA's Evolvable Mars Campaign (EMC) as an intermediate step for eventual human exploration and pioneering of the surface of Mars. A range of mission architectures is being evaluated in which human crews would explore one or both moons for as little as 14 days or for as long as 500 days with a variety of orbital and surface habitation and mobility options being considered. Relatively little is known about the orbital, surface, or subsurface characteristics of either moon. This makes them interesting but challenging destinations for human exploration missions during which crewmembers must be able to effectively conduct scientific exploration without being exposed to undue risks due to radiation, dust, micrometeoroids, or other hazards. A robotic precursor mission to one or both moons will be required to provide data necessary for the design and operation of subsequent human systems and for the identification and prioritization of scientific exploration objectives. This paper identifies and discusses considerations for the design of such a precursor mission based on current human mission architectures. Objectives of a Mars' moon precursor in support of human missions are expected to include: 1) identifying hazards on the surface and the orbital environment at up to 50-km distant retrograde orbits; 2) collecting data on physical characteristics for planning of detailed human proximity and surface operations; 3) performing remote sensing and in situ science investigations to refine and focus future human scientific activities; and 4) prospecting for in situ resource utilization. These precursor objectives can be met through a combination or remote sensing (orbital) and in-situ (surface) measurements. Analysis of spacecraft downlink signals using radio science techniques would measure the moon's mass, mass distribution, and gravity field, which will be necessary to enable trajectory planning

  18. Development of neural precursor cells from mouse embryonic stem cells

    Institute of Scientific and Technical Information of China (English)

    WU Xuan; LI Hai-di; Li Shu-nong; XU Hai-wei; XU Ling

    2001-01-01

    Objective: To explore the serum-free culture conditions for differentiating mouse embryonic stem cells (ES cells)into neural precursor cells (NPC) and compare the effects of human embryonic fibroblasts (HEF) as the feeder layer of ES with that of mouse embryonic fibroblasts (MEF)in vitro. Methods: Mouse ES cells were cultured in or not in feeder layer cells medium containing or not leukemia inhibitory factor to suppress their differentiation. Immunocytochemical method was used to identify NPC by detecting nestin antigen and alkaline phosphatase. Results: The ES cells cultured in HEF were positive to alkaline phosphatase. Serum-free medium allowed the differentiation of ES cells into NPC. Conclusion:HEF could replace MEF and keep the undifferentiated condition of ES cells with more benefits. NPC of high purity could be cultured from ES cells by serum-free culture method.

  19. Properties and Applications of Nanocrystalline Alloys from Amorphous Precursors

    CERN Document Server

    Idzikowski, Bogdan; Miglierini, Marcel

    2005-01-01

    Metallic (magnetic and non-magnetic) nanocrystalline materials have been known for over ten years but only recent developments in the research into those complex alloys and their metastable amorphous precursors have created a need to summarize the most important accomplishments in the field. This book is a collection of articles on various aspects of metallic nanocrystalline materials, and an attempt to address this above need. The main focus of the papers is put on the new issues that emerge in the studies of nanocrystalline materials, and, in particular, on (i) new compositions of the alloys, (ii) properties of conventional nanocrystalline materials, (iii) modeling and simulations, (iv) preparation methods, (v) experimental techniques of measurements, and (vi) different modern applications. Interesting phenomena of the physics of nanocrystalline materials are a consequence of the effects induced by the nanocrystalline structure. They include interface physics, the influence of the grain boundaries, the aver...

  20. C-type natriuretic peptide and its precursor

    DEFF Research Database (Denmark)

    Lippert, Solvej; Iversen, Peter; Brasso, Klaus;

    2015-01-01

    examined for CNP and CNP precursor (proCNP) concentrations in blood and seminal plasma. Furthermore, CNP and the CNP receptor (NPR-B) mRNA contents in tissue from prostate and seminal vesicles were analyzed by qPCR. RESULTS: CNP and NPR-B concentrations decreased with increasing tumor burden (p = 0......AIM: Seminal plasma offer a more organ-specific matrix for markers in prostatic disease. We hypothesized that C-type natriuretic peptide (CNP) expression may constitute such a new target. METHODS: Patients with benign prostatic hyperplasia, clinically localized and metastatic prostate cancer were.......0027 and p = 0.0096, respectively). In contrast, seminal plasma CNP and proCNP concentrations were markedly increased with increased tumor burden (p

  1. Clinical and biological significance of precursor lesions ofintrahepatic cholangiocarcinoma

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Cholangiocarcinoma (CC) is primarily a malignant tumorof older adults most prevalent in Southeast Asia, whereliver fluke infestation is high. However the etiology inwestern countries is unknown. Although the incidence ofextrahepatic cholangiocarcinoma has remained constant,incidence of intrahepatic CC (ICC) which differs inmorphology, pathogenesis, risk factors, treatment andprognosis is increasing. While this increase is associatedwith hepatitis C virus infection, chronic nonalcoholicliver disease, obesity, and smoking, the pathogenesisof ICC and molecular alterations underlying the carcinogenesisare not completely elucidated. Benignbiliary lesions such as biliary intraepithelial neoplasia,intraductal papillary neoplasm of the bile duct, vonMeyenburg complex or bile duct hamartoma, and bileduct adenoma have been associated with ICC. For eachof these entities, evidence suggests or supports a roleas premalignant lesions. This article summarized theimportant biological significance of the precursor lesionsof ICC and the molecular mechanisms that may beinvolved in intrahepatic cholangiocarcinogenesis.

  2. New Evaluation on the Preoxidation Extent of Different PAN Precursors

    Institute of Scientific and Technical Information of China (English)

    Wangxi ZHANG; Jie LIU; Jieying LIANG

    2004-01-01

    Structural changes in carbon fibers at each stage of, especially, preoxidation process are well known to play a great role in achieving the ultimate product quality. Differential scanning calorimetry (DSC), scanning electron microscope (SEM), density method and optical microscope were used to characterize the preoxidation extent. A conventional pproach, e.g., density aim, to evaluate the extent of preoxidation is not very exact. A DSC curve of a PAN precursor only can provide general information, major in the temperature regime of preoxidation reaction. However,the evaluation of a preoxidation extent, especially from conventional preoxidation temperature with a great span egime of 200~400℃, is put forward in this paper, in which the evolution of core/shell morphological structure is a kind of straightforward evidence.

  3. Morphology Controlling of the Ultrafine Cerium Dioxide (CeO2) Precursor

    Institute of Scientific and Technical Information of China (English)

    Jianqing CHEN; Zhigang CHEN; Jinchun LI

    2004-01-01

    The synthesis of ultrafine cerium dioxide precursor via homogeneous precipitation was studied. Mixed aqueous solution of anhydrous cerium nitrate and urea was first heated to 85℃ for 2 h, and the prepared suspension was then aged at room temperature for various periods of time. White precipitate was finally collected by centrifuging and washed with distilled water and anhydrous ethanol. The obtained cerium dioxide (CeO2) precursor was observed with SEM. It was found that the morphology and size of the precursor were strongly affected by aging time and stirring conditions (with or without stirring).The precipitated fine spherical particles of the precursor changed their shape from ellipse to slice or directly to slice. Fine spherical monodispersed (300 nm) precursor powders could be obtained by controlling the aging time. Stirring the solution also could change the reaction process and thus the morphology and size of the precursor were changed.

  4. The Unexpected Influence of Precursor Conversion Rate in the Synthesis of III-V Quantum Dots.

    Science.gov (United States)

    Franke, Daniel; Harris, Daniel K; Xie, Lisi; Jensen, Klavs F; Bawendi, Moungi G

    2015-11-23

    Control of quantum dot (QD) precursor chemistry has been expected to help improve the size control and uniformity of III-V QDs such as indium phosphide and indium arsenide. Indeed, experimental results for other QD systems are consistent with the theoretical prediction that the rate of precursor conversion is an important factor controlling QD size and size distribution. We synthesized and characterized the reactivity of a variety of group-V precursors in order to determine if precursor chemistry could be used to improve the quality of III-V QDs. Despite slowing down precursor conversion rate by multiple orders of magnitude, the less reactive precursors do not yield the expected increase in size and improvement in size distribution. This result disproves the widely accepted explanation for the shortcoming of current III-V QD syntheses and points to the need for a new generalizable theoretical picture for the mechanism of QD formation and growth.

  5. Nox2 and Nox4 influence neonatal c-kit+ cardiac precursor cell status and differentiation

    OpenAIRE

    Nadworny, Alyson S.; Guruju, Mallik R.; Poor, Daniel; Doran, Robert M.; Sharma, Ram V.; Kotlikoff, Michael I.; Davisson, Robin L.

    2013-01-01

    Redox status has emerged as critical in modulating stemness and lineage commitment in several precursor cell types. However, a role for redox genes, specifically NADPH oxidases (Nox), in cardiac precursor cells (CPCs) has not been established. We tested whether CPCs marked by type III receptor tyrosine kinase c-kit (c-kit+) exhibit a unique NADPH oxidase signature that confers precursor status and whether alterations in this profile are functionally linked to changes in lineage specification....

  6. Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish

    DEFF Research Database (Denmark)

    Koltowska, Katarzyna; Lagendijk, Anne Karine; Pichol-Thievend, Cathy;

    2015-01-01

    Lymphatic vessels arise chiefly from preexisting embryonic veins. Genetic regulators of lymphatic fate are known, but how dynamic cellular changes contribute during the acquisition of lymphatic identity is not understood. We report the visualization of zebrafish lymphatic precursor cell dynamics...... during fate restriction. In the cardinal vein, cellular commitment is linked with the division of bipotential Prox1-positive precursor cells, which occurs immediately prior to sprouting angiogenesis. Following precursor division, identities are established asymmetrically in daughter cells; one daughter...

  7. Disrupted yeast mitochondria can import precursor proteins directly through their inner membrane

    OpenAIRE

    1989-01-01

    Import of precursor proteins into the yeast mitochondrial matrix can occur directly across the inner membrane. First, disruption of the outer membrane restores protein import to mitochondria whose normal import sites have been blocked by an antibody against the outer membrane or by a chimeric, incompletely translocated precursor protein. Second, a potential- and ATP-dependent import of authentic or artificial precursor proteins is observed with purified inner membrane vesicles virtually free ...

  8. Non-invasive method for in vivo detection of chlorophyll precursors

    DEFF Research Database (Denmark)

    Kristiansen, Kim Anker; Khrouchtchova, Anastassia; Stenbæk, Anne;

    2009-01-01

    Traditionally chlorophyll (Chl) and Chl precursors have been studied in vitro or in leaf tissue at low temperature. These methods are destructive and make it impossible to work with the same individual plant later on. In this paper we present a method for in vivo detection of Chl and its precursors...... is compared to current methods. Furthermore, we report on optimization of the spectral scanning method with the aim to minimize the excitation light-evoked photo-conversion of the chlorophyll precursors....

  9. Fluidized bed as a solid precursor delivery system in a chemical vapor deposition reactor

    OpenAIRE

    Vahlas, Constantin; Caussat, Brigitte; Senocq, François; Gladfelter, Wayne L.; Sarantopoulos, Christos; Toro, David; Moersch, Tyler

    2005-01-01

    Chemical vapor deposition (CVD) using precursors that are solids at operating temperatures and pressures, presents challenges due to their relatively low vapor pressures. In addition, the sublimation rates of solid state precursors in fixed bed reactors vary with particle and bed morphology. In a recent patent application, the use of fluidized bed (FB) technology has been proposed to provide high, reliable, and reproducible flux of such precursors in CVD processes. In the present contribution...

  10. Apontamentos sobre o pensamento de Carl Schmitt: um intelectual nazista

    Directory of Open Access Journals (Sweden)

    Cândido Moreira Rodrigues

    2005-01-01

    Full Text Available Apresentaremos um esboço de alguns pontos do pensamento do jurista alemão Carl Schmitt, fundamentalmente no período da República de Weimar e parte do regime nazista. Será dada maior atenção à sua relação com o conceito de decisão e como tal conceito permeou seus escritos em torno da crítica ao liberalismo/parlamentarismo de Weimar; atentaremos ainda para sua defesa da existência de um Estado Forte como produto da inevitabilidade existencial, da distinção social entre amigos-inimigos e de uma homogeneidade racial e “democrática”, idéias que serviram de esteio ao regime nazista. Tomamos como base de análise as seguintes obras suas em edições mais recentes: A Ditadura 1921, Teologia Política 1922, A Situação intelectual (espiritual do sistema parlamentar atual 1923 e O Conceito do Político 1927. Objetivamos, com assim, contribuir para uma reflexão mais atenta a respeito de um certo "revisionismo schmitiano” que busca, por todos os meios, apresentá-lo como pensador democrático e minimizar sua ligação com o regime nazista, no período de 1933 a 1936 quando esteve ligado ao partido de Hitler. Com isso, se objetiva alertar para o reavivamento de suas idéias de extrema direita, sobretudo em países como Alemanha, Áustria, Itália e, mais recentemente, nos Estados Unidos. Na reflexão sobre pontos de seu pensamento, nos apoiaremos nos escritos de pensadores como Richard Wolin, Kal Löwith, Nicolas Tertulian, Heinrich Meier, Jean-Luc Evard, Jürgen Habermas e no Brasil, Roberto Romano e Bernardo Ferreira.

  11. Síndrome de Asperger: relato de um caso

    Directory of Open Access Journals (Sweden)

    Letícia Viana Pereira

    2012-04-01

    Full Text Available Objetivo: O presente estudo tem como real objetivo o relato de um caso de Síndrome de Asperger comprado às características descritas na literatura. Metodologia: A partir de um relato de um caso atendido na Clínica Escola de Fonoaudiologia do Centro Universitário Metodista Izabela Hendrix, determinadas características foram comparadas com o descrito na literatura pertinente. Os trabalhos foram lidos, fichados e agrupados, segundos algumas características de abordagem, para posterior análise e comparação com o caso clínico relatado. Discussão e resultados: As crianças com Síndrome de Asperger são, em geral, diferentes entre si. Freqüentemente procedimentos realizados que podem ser indicados para uma criança seriam inadequados para outra. Assim, sugestões apresentadas pela literatura devem ser consideradas para melhorar a assistência à criança, como a compreensão mais abrangente e a reflexão aprofundada em relação a cada caso em específico. Conclusão: O acompanhamento e tratamento fonoaudiológico nesses casos, é de suma importância para o desenvolvimento o mais próximo possível do considerado formal na linguagem e na comunicação destes indivíduos. Vivências clínicas mostram as estratégias que podem ser sugeridas para estas crianças, lembrando que casa criança possui suas particularidades, que devem sempre ser levadas em consideração.

  12. Internet e Cultura: um novo olhar, veloz e voraz

    Directory of Open Access Journals (Sweden)

    Wilson de Oliveira Souza

    1999-01-01

    Full Text Available Em cada piscadela que damos, um novo mundo enxergamos. Com a globalização, o modo de ver o mundo muda radicalmente, principalmente devido ao complexo ritmo ditado pelas relações entre o meio ambiente e seus usuários. De forma sintetizada, podemos explicar que a globalização é resultado da terceira revolução tecnológica (tecnologias ligadas à busca, processamento, difusão e transmissão de informações; inteligência artificial; engenharia genética, da formação de áreas de livre comércio e blocos econômicos interligados (como o Mercosul, a União Européia e o Nafta e da crescente interligação e interdependência dos mercados físicos e financeiros em escala planetária. Essa trinca é responsável pela alteração, principalmente, da nova forma de enxergarmos a cultura, aceitando que a mundialização da cultura é um processo em curso, não concluído ainda, na qual as formas culturais nacionais ou locais entram em contato rapidamente. Com isso, quedam as barreiras territoriais, forçam as mediações e criam, no dizer de Featherstone, a "terceira cultura", entendendo como "um conjunto de práticas, conhecimentos, convenções e estilos de vida que se desenvolvem de modo a se tornar cada vez mais independente dos Estados-Nação".

  13. Coerência textual: um estudo com jovens e adultos

    Directory of Open Access Journals (Sweden)

    Gonçalves Fabíola

    2003-01-01

    Full Text Available A coerência é um fenômeno lingüístico responsável pela construção de sentido que garante a interpretabilidade de um texto. As investigações conduzidas pela psicologia cognitiva têm investido esforços no exame da coerência a partir da perspectiva daqueles que recebem o texto. Este estudo examinou se o estabelecimento da coerência textual está relacionado à aquisição da leitura e da escrita com jovens e adultos, em processo de alfabetização, em uma situação de produção de texto. Alunos entre 15 a 45 anos, matriculados no 1º e 2º ciclos da Educação Básica de Jovens e Adultos de uma escola pública, foram individualmente solicitados a produzir oralmente uma história original. As histórias foram analisadas em função de indicadores específicos, agrupados em um sistema de análise, o qual expressa níveis distintos acerca do estabelecimento da coerência. Comparações entre os ciclos foram realizadas. Os resultados obtidos corroboram estudo realizado com crianças. Há indicadores mais fáceis de serem estabelecidos do que outros. Pode-se argumentar que a escolaridade contribui para o estabelecimento da coerência na produção de história.

  14. BerkeleyGW: A massively parallel computer package for the calculation of the quasiparticle and optical properties of materials and nanostructures

    Science.gov (United States)

    Deslippe, Jack; Samsonidze, Georgy; Strubbe, David A.; Jain, Manish; Cohen, Marvin L.; Louie, Steven G.

    2012-06-01

    BerkeleyGW is a massively parallel computational package for electron excited-state properties that is based on the many-body perturbation theory employing the ab initio GW and GW plus Bethe-Salpeter equation methodology. It can be used in conjunction with many density-functional theory codes for ground-state properties, including PARATEC, PARSEC, Quantum ESPRESSO, SIESTA, and Octopus. The package can be used to compute the electronic and optical properties of a wide variety of material systems from bulk semiconductors and metals to nanostructured materials and molecules. The package scales to 10 000s of CPUs and can be used to study systems containing up to 100s of atoms. Program summaryProgram title: BerkeleyGW Catalogue identifier: AELG_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AELG_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Open source BSD License. See code for licensing details. No. of lines in distributed program, including test data, etc.: 576 540 No. of bytes in distributed program, including test data, etc.: 110 608 809 Distribution format: tar.gz Programming language: Fortran 90, C, C++, Python, Perl, BASH Computer: Linux/UNIX workstations or clusters Operating system: Tested on a variety of Linux distributions in parallel and serial as well as AIX and Mac OSX RAM: (50-2000) MB per CPU (Highly dependent on system size) Classification: 7.2, 7.3, 16.2, 18 External routines: BLAS, LAPACK, FFTW, ScaLAPACK (optional), MPI (optional). All available under open-source licenses. Nature of problem: The excited state properties of materials involve the addition or subtraction of electrons as well as the optical excitations of electron-hole pairs. The excited particles interact strongly with other electrons in a material system. This interaction affects the electronic energies, wavefunctions and lifetimes. It is well known that ground-state theories, such as standard methods

  15. Um modelo de hérnia incisional em coelhos

    Directory of Open Access Journals (Sweden)

    Aydos Ricardo Dutra

    1997-01-01

    Full Text Available Apresenta-se um modelo de confecção de hérnia incisional em coelhos. Foram utilizados 15 animais nos quais produziu-se hérnia incisional mediante secção completa da parede abdominal e da realização de sutura do plano músculo-aponeurótico à tela subcutânea e à derme seguido do fechamento da pele. Foram obtidas incisionais em todos os animais.

  16. Solar Battery Charger in CMOS 0.25 um Technology

    OpenAIRE

    Tao Wang; Chang-Ching Huang; Tian-Jen Wang

    2014-01-01

    A solar cell powered Li-ion battery charger in CMOS 0.25um is proposed. The solar battery charger consists of a DC/DC boost converter and a battery charger. The voltage generated by a solar cell is up converted from 0.65V to 1.8V, which is used as the VDD of the battery charger.  In this way, the solar battery charger automatically converts solar energy to electricity and stores it directly to a Li-ion rechargeable battery. In this system, a super capacitor is needed as a charge buffer betwee...

  17. A educação...um direito para todos

    OpenAIRE

    Machado, Marina de Fátima Pereira

    2015-01-01

    O presente relatório final, realizado no âmbito do Mestrado em Educação Pré-Escolar, na Escola Superior de Educação de Coimbra do Instituto Politécnico de Coimbra (...) pretende ser uma análise crítica e reflexiva da iniciação à prática educativa, com o intuito de alcançar um maior desenvolvimento de competências profissionais. (...)

  18. Comando de um Servomecanismo usando Visão Computacional

    OpenAIRE

    Ricardo Carneiro Ferreira; João Manuel R. S. Tavares; Francisco Freitas

    2003-01-01

    Neste artigo é apresentada uma metodologia para controlar um servomecanismo usando visão computacional. As imagens de controlo,baseadas na linguagem gestual, são obtidas por intermédio de uma webcam genérica e processadas praticamente em tempo real. Aordem de comando em causa é reconhecida por diferença dos histogramas de orientação da imagem associada e das imagens deordens preestabelecidas. Estas imagens de ordens são guardadas durante o processo de aprendizagem do sistema de controlo. I...

  19. Conceptualização de um projecto urbano

    OpenAIRE

    Rodrigues, João André Preza Vieira

    2015-01-01

    Dissertação apresentada na Universidade de Lisboa - Faculdade de Arquitetura, para obtenção do Grau de Mestre em Arquitetura. "Criação de um ambiente mais propício à vida e intencionalidade estética são os caracteres estáveis da arquitectura; estes aspectos sobressaem em qualquer pesquisa positiva e iluminam a cidade como criação humana. Mas para dar forma concreta à sociedade, e sendo intimamente congénita com esta e com a natureza, a arquitectura é diferente, de modo original, de qualque...

  20. Balanced scorecard em unidades hospitalares: um estudo de caso

    OpenAIRE

    Silva, Tiago Alexandre Milhães da

    2013-01-01

    Dissertação apresentada ao Instituto Politécnico do Porto para obtenção do Grau de Mestre em Gestão das Organizações, Ramo de Gestão de Empresas Orientador: Professor Doutor Orlando Manuel Martins Marques de Lima Rua A implementação de estratégias surge como um dos grandes desafios na atualidade para as organizações. Para tal é necessário a existência de uma ferramenta completa que demonstre quais os fatores essenciais para obter o melhor desempenho empresarial: o Balanced Scor...