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Sample records for belgian post-menopausal women

  1. Validity and Reproducibility of a Self-Administered Semi-Quantitative Food-Frequency Questionnaire for Estimating Usual Daily Fat, Fibre, Alcohol, Caffeine and Theobromine Intakes among Belgian Post-Menopausal Women

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    Selin Bolca

    2009-01-01

    Full Text Available A novel food-frequency questionnaire (FFQ was developed and validated to assess the usual daily fat, saturated, mono-unsaturated and poly-unsaturated fatty acid, fibre, alcohol, caffeine, and theobromine intakes among Belgian post-menopausal women participating in dietary intervention trials with phyto-oestrogens. The relative validity of the FFQ was estimated by comparison with 7 day (d estimated diet records (EDR, n 64 and its reproducibility was evaluated by repeated administrations 6 weeks apart (n 79. Although the questionnaire underestimated significantly all intakes compared to the 7 d EDR, it had a good ranking ability (r 0.47-0.94; weighted κ 0.25-0.66 and it could reliably distinguish extreme intakes for all the estimated nutrients, except for saturated fatty acids. Furthermore, the correlation between repeated administrations was high (r 0.71-0.87 with a maximal misclassification of 7% (weighted κ 0.33-0.80. In conclusion, these results compare favourably with those reported by others and indicate that the FFQ is a satisfactorily reliable and valid instrument for ranking individuals within this study population.

  2. Biomarkers of vascular function in pre- and recent post-menopausal women of similar age

    DEFF Research Database (Denmark)

    Nyberg, Michael Permin; Seidelin, Kaare; Rostgaard Andersen, Thomas; Neumann Overby, Nickie; Hellsten, Ylva; Bangsbo, Jens

    2014-01-01

    Menopause is associated with an accelerated decline in vascular function, however, whether this is an effect of age and/or menopause and how exercise training may affect this decline remains unclear. We examined a range of molecular measures related to vascular function in matched pre- and post-menopausal...... women before and after 12 weeks of exercise training. Thirteen pre-menopausal and ten recently post-menopausal (1.6±0.3 (mean±SEM) years after final menstrual period) women only separated by three years (48±1 vs. 51±1 years) were included. Before training, diastolic blood pressure, soluble intercellular...... adhesion molecule-1 (sICAM-1) and skeletal muscle expression of thromboxane A synthase were higher in the post-menopausal women compared to the pre-menopausal women, all indicative of impaired vascular function. In both groups, exercise training lowered diastolic blood pressure, the levels of sICAM-1...

  3. Alzheimer disease in post-menopausal women: Intervene in the critical window period

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    Nayer Jamshed

    2014-01-01

    Full Text Available Alzheimer disease (AD is a crippling neurodegenerative disorder. It is more common in females after menopause. Estrogen probably has a protective role in cognitive decline. Large amount of research has been carried out to see the benefits of hormone replacement therapy with regards to Alzheimer still its neuroprotective effect is not established. Recent studies suggest a reduced risk of AD and improved cognitive functioning of post-menopausal women who used 17 β-estradiol in the critical period. Use of 17 β-estradiol in young and healthy post-menopausal women yields the maximum benefit when the neurons are intact or neuronal stress has just started. Hence intervention in the critical period is key in the prevention or delay of AD in post-menopausal women.

  4. Ginger Supplementation Enhances Working Memory of the Post-Menopause Women

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    Naritsara Saenghong

    2011-01-01

    Full Text Available Problem statement: Cognitive impairment is one important problem in post-menopausal women. Although hormone therapy can improve this condition, it also produces adverse effect. Recent findings showed that this condition could be mitigated by the herb. Ginger or Zingiber officinale Roscoe, a plant in a family of Zingiberaceae, was previously demonstrated the neuroprotection and cognitive enhancing effects. Therefore, this study was set up to determine whether ginger rhizome extract could improve attention and working memory of the post-menopausal women. Approach: Sixty healthy post-menopausal women were randomly assigned to receive either placebo or standardized plant extract at doses of 400 and 800 mg once daily for 3 months. After the assessment of biographic information, they were evaluated the working memory and cognitive function using computerized battery test and the auditory oddball paradigm of event related potential before and after 3-month of intervention. Results: The ginger treated group decreased N100 and P300 latencies but increased N100 and P300 amplitudes in accompany with the enhanced working memory including the power of attention, continuity of attention, speed and quality of memory. Conclusion: Our results suggested that ginger is the potential cognitive enhancer for post-menopausal women. However, further researches are still required.

  5. Study on the serum prolactin (PRL) level in post-menopausal women

    International Nuclear Information System (INIS)

    Objective: To explore the clinical value of determination of serum PRL levels inpost-menopausal women. Methods: Serum PRL levels were determined with RIA in 596 post-menopausal women (age 45-59, mean 55). Results: The normal range of serum PRL level in this laboratory was 0-30 ng/ml. Among the 596 women tested, 77(13%) had their PRL levels above 30 ng/ml. Further investigation with CT and/or MRI revealed presence of micro-pituitary-adenoma in 31 of the Symptoms of menopausal syndrome and osteoporosis were much more severe in women with hyperprolactinemia then in those without. Conclusion: As hyperprolactinemia might be a high risk factor for development of breast cancer, hormone replacement therapy (HRT) in menopausal women with hyperprolactinemia should be applied very cautiously, even withheld at all. Determination of serum prolactin levels in post-menopausal women is of practical clinical value. (authors)

  6. Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women

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    Cassidy, A.; Albertazzi, P.; Nielsen, I. L.;

    2006-01-01

    improve endothelial function. For menopausal symptoms there is currently limited evidence that soyabean-protein isolates, soyabean foods or red-clover (Trifolium pratense L.) extract are effective but soyabean isoflavone extracts may be effective in reducing hot flushes. There are too few RCT studies to...... reach conclusions on the effects of isoflavones on breast cancer, colon cancer, diabetes or cognitive function. The health benefits of soyabean phyto-oestrogens in healthy post-menopausal women are subtle and even some well-designed studies do not show protective effects. Future studies should focus on......A consensus view of soyabean phyto-oestrogens in clinical interventions in post-menopausal women is presented that is based on data from the EU-funded project Phytohealth. The phyto-oestrogens, primarily genistein and daidzein, were given as soyabean-protein isolates, whole-soyabean foods or...

  7. Phenolic metabolites of anthocyanins following a dietary intervention study in post-menopausal women

    OpenAIRE

    de Ferrars, Rachel M; Cassidy, Aedín; Curtis, Peter; Kay, Colin D.

    2014-01-01

    Scope Numerous studies feeding anthocyanin-rich foods report limited bioavailability of the parent anthocyanins. The present study explores the identity and concentration of the phenolic metabolites of anthocyanins in humans. Methods and results Anthocyanin metabolites were quantified in samples collected from a previously conducted 12-wk elderberry intervention study in healthy post-menopausal women. Individual 1-, 2- and 3-h post-bolus urine samples and pooled plasma samples following acute...

  8. Vascular and Nutrigenomic effects of grapefruit flavanones consumption: A RCT in post-menopausal women

    OpenAIRE

    Habauzit, Veronique; Milenkovic, Dragan; Verny, Marie-Anne; Barber Chamoux, Nicolas; Bobby, Céline; Mazur, André; Dubray, Gerard; Morand, Christine

    2015-01-01

    The consumption of citrus fruits is associated with health benefits. However, clinical data regarding the effects of grapefruit flavanone consumption on vascular function are lacking. The present clinical study aimed at 1) characterizing the specific role of naringin in the effect of a long-term consumption of grapefruit juice on vascular function in humans and 2) analyzing changes in PBMCs transcriptome profile induced by grapefruit naringin. 52 healthy post-menopausal women were enrolled...

  9. Calcium status in premenopausal and post menopausal women

    International Nuclear Information System (INIS)

    Background: In postmenopausal women, the two major causes of bone loss are oestrogen deficiency after menopause and age related processes. Bone turnover increases to high levels and oestrogen deficiency may induce calcium loss by indirect effects on extra skeletal calcium homeostasis. Objective of this study was to evaluate calcium status in pre-menopausal and postmenopausal women. Methods: This cross sectional study was carried out in 34 premenopausal women and 33 postmenopausal women, in Department of Physiology, Services Institute of Medical Sciences, Lahore. Height and weight of each woman were taken to find out the body mass index (BMI). Serum calcium, parathyroid hormone and calcitonin levels of each subject were determined. Results: Premenopausal women were obese (BMI>30 Kg/m/sup 2/) while postmenopausal women were overweight (BMI>25 Kg/m/sup 2/). Serum calcium levels were significantly lower in postmenopausal women than in pre-menopausal women, while serum parathyroid hormone levels were significantly higher in postmenopausal woman. Serum calcitonin level was not significantly different in the two groups. Conclusion: Postmenopausal women are calcium deficient and have increased bone turnover as indicated by increased serum parathyroid hormone levels. (author)

  10. Reproductive history and pancreatic cancer incidence and mortality in a cohort of post-menopausal women

    OpenAIRE

    Stevens, Richard J.; Roddam, Andrew W; Green, Jane; Pirie, Kirstin; Bull, Diana; Reeves, Gillian K.; Beral, Valerie

    2009-01-01

    There is inconsistent evidence about the effect of reproductive history on women’s risk of pancreatic cancer. In the Million Women Study, a prospective cohort of middle-aged women in the UK, we examined associations between reproductive history and pancreatic cancer incidence and mortality, controlling for age, socioeconomic status, geographic region, body mass index, smoking and history of diabetes. During 7.1 million person-years of follow-up in 995,192 post-menopausal women there were 1,18...

  11. Dietary Factors Contributing to Osteoporosis among Post Menopausal Saudi Women

    Science.gov (United States)

    Alsaif, Mohammed A.; Khan, Latifa K.; Alhamdan, Adel A. H.; Alorf, Saada M.; Al-Othman, Abdulaziz M.; Makki, Rabab J.

    This study was designed to investigate the dietary components which are likely to contribute to osteoporosis in postmenopausal Saudi women. In the present study, 36 osteoporotic postmenopausal and 25 healthy postmenopausal women as cases and controls respectively were selected from Armed Forces Hospital, Riyadh, Saudi Arabia. The study has designed to collect the data about the general characteristics (age, marital status, education, number of pregnancies, activity level, income and housing), anthropometric measurements, medical history and dietary intake by using both the methods (24 h recall, food frequency questionnaire). Serum samples were analyzed for calcium, phosphorus, vitamin D and Para Thyroid Hormone (PTH) and they were correlated with Bone Mineral Density (BMD). Food intake items were correlated with hip, neck and spin BMD. In results, cases found significantly older than controls and had history of bone fractures. Cases were consumed significantly less dietary calcium than controls. Serum parameters did not show any significant differences. However significant correlation was found between serum level of PTH and calcium with BMD of spine and right neck femur respectively. Banana and Mataziz (locally prepared dish with vegetables) showed positive correlation with hip BMD. A negative significant correlation was found between Arabian coffee and right neck femur BMD. In conclusion, Saudi women require encouragement to consume adequate amounts of calcium, fruits and vegetables in combination with maintaining a daily physical activity and space in child birth.

  12. PREVALENCE OF DRY EYE IN POST - MENOPAUSAL WOMEN

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    Pujari

    2015-09-01

    Full Text Available Dry eye refers to a heterogeneous group of conditions all characterized by inadequate lubrication of ocular surface. Dry eye is a potentially serious and chronic condition. It may severely limit a person's activity, and in extreme cases cause blindness. Po stmenopausal dry eye syndrome has frustrated patients, researchers and clinicians due to the paucity of successful treatment options and difficulty in assessing efficacy of treatment modalities. Hence early detection and treatment is necessary. AIM: This s tudy is to assess the prevalence of dry eye in postmenopausal women to prevent complications by early detection and management. MATERIAL AND METHODS: In this prospective study, 100 subjects were included in the study. Informed written consent was obtained from all patients. Ethical committee approval was taken. The study was conducted in Basawes h war teaching and general hospital (MR Medical college Kalburgi Karnataka between January 2014 to June 2014. Hundred postmenopausal women were categorized based on age of the patients into three groups: Group 1: 45 - 55 years, Group 2: 55 - 65 years, Group 3: 65 - 75 years. They were also classified based on: 1.Occupation, 2.Rural/urban dwelling, 3. Laterality of dry eye. RESULTS: In our study, most commonly dry eye manife sted in 65 - 75 years age group(66.6%, and more commonly seen in rural population(65%, and in people with outdoor occupation in all age group, and bilateral in all age group. CONCLUSION : Our study was compared with other studies on dry eye, and results wer e found to be in comparison with them. Hence dry eye needs to be periodically evaluated and to be treated accordingly.

  13. Analysis of lipid status, body mass index and waist-hip ratio in post-menopausal women

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    Lejla Mešalić

    2012-09-01

    Full Text Available Introduction: Menopause is the absence of menses in the period longer that one year. It is widely accepted that menopause leads to changes in hormonal status, metabolism and lipid profi le. The aim of this study wasto analyze the infl uence of menopause on the concentrations of lipids, lipoproteins and also the influence of body mass index (BMI and waist-hip ratio (WHR on lipid profi le in post-menopausal women.Methods: Sixty post-menopausal women of average age of 52.82 years were compared to a group of 34 pre-menopausal women average age of 47.92 years.Results: Post-menopausal women had higher, but non signifi cant (p>0.05 concentrations of total cholesterol, very low density lipoproteins (VLDL, low density lipoproteins (LDL and triglycerides than pre-menopausal women. The concentration of high density lipoproteins (HDL was significantly lower in post-menopausal women than pre-menopausal (p<0.05. The concentration of apolipoprotein B was also signifi cantly higher in post-menopausal women (p<0.05, but the concentrations of apolipoprotein and lipoprotein (a were lowerbut without signifi cance (p>0.05. There was no difference between body mass index (BMI and waste-hip ratio (WHR, but the WHR has shown as a signifi cant predictor of the LDL and cholesterol concentrations inpost-menopausal women.Conclusion: We can conclude that menopause leads to changes in lipid profi le by lowering of HDL and increasing the levels of apolipoprotein B, that increases the risk for cardiovascular disease. The WHR is thesignifi cant predictor of cardiovascular risk in post-menopausal women.

  14. Physical Activity Level of Post-menopausal Women with Low Bone Mineral Density.

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    Dallanezi, Glauber; Freire, Beatriz Funayama Alvarenga; Nahás, Eliana Aguiar Petri; Nahás-Neto, Jorge; Corrente, José Eduardo; Mazeto, Gláucia Maria Ferreira da Silva

    2016-05-01

    Introduction Proper physical activity is related to the prevention and the treatment of osteoporosis. Purpose To assess the level of physical activity (PA) in post-menopausal women with low bone mineral density (BMD). Methods This cross-sectional clinical study included 123 post-menopausal women. The inclusion criteria were: age of ≥ 45 years with last menses at least 12 months prior to the initiation of the study, and bone density scan (BDS) values measured over the preceding 12 months. Women with severe osteoarthritis were excluded. Women were allocated into three groups, according to BMD measured by BDS [osteoporosis (OP; 54 women), osteopenia (35 women), and normal bone density (NBD; 35 women)], and compared for general, clinical, and anthropometric data, and for PA level. The latter was assessed using the International Physical Activity Questionnaire (IPAQ), in metabolic equivalent of task (MET) units. Participants were classified as sedentary, active or very active. Quantitative variables were compared using ANOVA followed by Tukey's test. Associations between qualitative variables were tested by Chi-square (χ2) or Fisher's exact test. In order to check for differences among groups and IPAQ domains, a generalized linear model with Gamma distribution was adjusted for values in METs. Results The OP group differed from the NBD group regarding age (61.8 ± 10.1 and 52.9 ± 5.4 years), percentage of participants with self-declared white ethnicity (43.9 and 28.0%), body mass index (BMI - 25.7 ± 5.4 and 30.9 ± 5.1 kg/m(2)), and time since menopause (15.5 ± 7.5 and 5.8 ± 4.5 years). Smoking rates were higher in the OP (55.6%) and NBD groups (33.3%) than in the osteopenia group (11.1%). Within the OP group, the rate of subjects with sedentary lifestyles was higher (42.6%), and time spent sitting was greater (344.3 ± 204.8 METs) than in the groups with osteopenia (20.0% and 300.9 ± 230.6 METs) and NBD (17.7% and 303

  15. Expression of estrogen receptors in the pelvic floor of pre- and post-menopausal women presenting pelvic organ prolapse

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    Marie Laure Kottler

    2011-10-01

    Full Text Available The precise role of estrogen in the pathogenesis of pelvic organ prolapse (POP is still unclear, while the results concerning the effect of selective estrogen receptor modulators on pelvic organ prolapse are contradictory. Our aim was to test whether alteration in the expression of estrogen receptors in the pelvic floor of preand post-menopausal women is related to genital prolapse status. The mRNA levels of ERα and ERβ in 60 biopsy specimens were measured. Significantly higher expression of ERα and higher ERα/ERβ ratio were demonstrated in post-menopausal women compared to pre-menopausal women. Higher expression of ERα and higher ERα/ERβ ratio were detected in all studied groups with POP, thus it did not reach significance in the post-menopausal group. Pre-menopausal and post-menopausal women presenting pelvic organ prolapse had no difference in the ERα expression. Our preliminary study may indicate that pelvic organ prolapse is associated with higher expression of ERα/ERβ in the pelvic floor of both pre- and post-menopausal women; thus not reaching statistical significance in the post-menopausal women was probably due to the group’s size. We believe that the inevitable changes in the estrogen receptor expression over women’s different lifetimes may affect the risk of genital prolapse progression, and might contribute to the further search for appropriate selective estrogen receptor modulators as a treatment for women with pelvic organ prolapse. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 521–527

  16. Impact of Estrogen Therapy on Lymphocyte Homeostasis and the Response to Seasonal Influenza Vaccine in Post-Menopausal Women.

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    Flora Engelmann

    Full Text Available It is widely recognized that changes in levels of ovarian steroids modulate severity of autoimmune disease and immune function in young adult women. These observations suggest that the loss of ovarian steroids associated with menopause could affect the age-related decline in immune function, known as immune senescence. Therefore, in this study, we determined the impact of menopause and estrogen therapy (ET on lymphocyte subset frequency as well as the immune response to seasonal influenza vaccine in three different groups: 1 young adult women (regular menstrual cycles, not on hormonal contraception; 2 post-menopausal (at least 2 years women who are not receiving any form of hormone therapy (HT and 3 post-menopausal hysterectomized women receiving ET. Although the numbers of circulating CD4 and CD20 B cells were reduced in the post-menopausal group receiving ET, we also detected a better preservation of naïve B cells, decreased CD4 T cell inflammatory cytokine production, and slightly lower circulating levels of the pro-inflammatory cytokine IL-6. Following vaccination, young adult women generated more robust antibody and T cell responses than both post-menopausal groups. Despite similar vaccine responses between the two post-menopausal groups, we observed a direct correlation between plasma 17β estradiol (E2 levels and fold increase in IgG titers within the ET group. These findings suggest that ET affects immune homeostasis and that higher plasma E2 levels may enhance humoral responses in post-menopausal women.

  17. Impact of Estrogen Therapy on Lymphocyte Homeostasis and the Response to Seasonal Influenza Vaccine in Post-Menopausal Women

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    Engelmann, Flora; Rivera, Andrea; Park, Byung; Messerle-Forbes, Marci; Jensen, Jeffrey T.; Messaoudi, Ilhem

    2016-01-01

    It is widely recognized that changes in levels of ovarian steroids modulate severity of autoimmune disease and immune function in young adult women. These observations suggest that the loss of ovarian steroids associated with menopause could affect the age-related decline in immune function, known as immune senescence. Therefore, in this study, we determined the impact of menopause and estrogen therapy (ET) on lymphocyte subset frequency as well as the immune response to seasonal influenza vaccine in three different groups: 1) young adult women (regular menstrual cycles, not on hormonal contraception); 2) post-menopausal (at least 2 years) women who are not receiving any form of hormone therapy (HT) and 3) post-menopausal hysterectomized women receiving ET. Although the numbers of circulating CD4 and CD20 B cells were reduced in the post-menopausal group receiving ET, we also detected a better preservation of naïve B cells, decreased CD4 T cell inflammatory cytokine production, and slightly lower circulating levels of the pro-inflammatory cytokine IL-6. Following vaccination, young adult women generated more robust antibody and T cell responses than both post-menopausal groups. Despite similar vaccine responses between the two post-menopausal groups, we observed a direct correlation between plasma 17β estradiol (E2) levels and fold increase in IgG titers within the ET group. These findings suggest that ET affects immune homeostasis and that higher plasma E2 levels may enhance humoral responses in post-menopausal women. PMID:26859566

  18. Comparison of myocardial function between post-menopausal and pre-menopausal women: evaluation by gated myocardial SPECT

    International Nuclear Information System (INIS)

    In addition to inhibiting coronary atherosclerosis, estrogen is expected to have protective effects on cardiac myocytes. We investigated the difference in myocardial functional parameters evaluated by gated myocardial SPECT after adenosine-stress between post-menopausal and pre-menopausal healthy women. This study included 22 healthy post-menopausal women (mean age: 53.0 yr) and 20 pre-menopausal women (mean age: 43.0 yr) who performed Tc-99m tetrofosmin gated myocardial SPECT after adenosine-stress. Measured hemodynamic parameters, EDV, ESV, stroke volume, EF, cardiac output and cardiac index were compared between the two groups. For comparison, similar-aged two male groups with matched numbers were also studied. There was no significant difference in hemodynamic parameters. EDV, ESV, stroke volume, EF, or cardiac output between the post-menopausal and pre-menopausal women. However, post-menopausal women have a smaller cardiac index (mean: 1.95 L/min/m2 vs 2.20 L/min/m2; p=0.045) and adenosine-induced HR increase (mean : 80.5/min vs 89.7/min ; p=0.03), compared to the pre-menopausal women. On the contrary, the two male groups of the same age range and numbers with the women groups showed no significant difference in any myocardial parameters. These results suggest that menopause may be correlated with reduced increase in cardiac index and HR increase after adenosine-stress

  19. Comparison of myocardial function between post-menopausal and pre-menopausal women: evaluation by gated myocardial SPECT

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    Hwang, K. H.; Choa, Won Sick; Yoon, Min Ki [Gachon Medical School, Gil Hospital, Incheon (Korea, Republic of)

    2005-07-01

    In addition to inhibiting coronary atherosclerosis, estrogen is expected to have protective effects on cardiac myocytes. We investigated the difference in myocardial functional parameters evaluated by gated myocardial SPECT after adenosine-stress between post-menopausal and pre-menopausal healthy women. This study included 22 healthy post-menopausal women (mean age: 53.0 yr) and 20 pre-menopausal women (mean age: 43.0 yr) who performed Tc-99m tetrofosmin gated myocardial SPECT after adenosine-stress. Measured hemodynamic parameters, EDV, ESV, stroke volume, EF, cardiac output and cardiac index were compared between the two groups. For comparison, similar-aged two male groups with matched numbers were also studied. There was no significant difference in hemodynamic parameters. EDV, ESV, stroke volume, EF, or cardiac output between the post-menopausal and pre-menopausal women. However, post-menopausal women have a smaller cardiac index (mean: 1.95 L/min/m2 vs 2.20 L/min/m2; p=0.045) and adenosine-induced HR increase (mean : 80.5/min vs 89.7/min ; p=0.03), compared to the pre-menopausal women. On the contrary, the two male groups of the same age range and numbers with the women groups showed no significant difference in any myocardial parameters. These results suggest that menopause may be correlated with reduced increase in cardiac index and HR increase after adenosine-stress.

  20. Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma

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    Chung Bong

    2011-08-01

    Full Text Available Abstract Background To evaluate the metabolic changes in urinary steroids in pre- and post-menopausal women and men with papillary thyroid carcinoma (PTC. Methods Quantitative steroid profiling combined with gas chromatography-mass spectrometry was used to measure the urinary concentrations of 84 steroids in both pre- (n = 21, age: 36.95 ± 7.19 yr and post-menopausal female (n = 19, age: 52.79 ± 7.66 yr, and male (n = 16, age: 41.88 ± 8.48 yr patients with PTC. After comparing the quantitative data of the patients with their corresponding controls (pre-menopause women: n = 24, age: 33.21 ± 10.48 yr, post-menopause women: n = 16, age: 49.67 ± 8.94 yr, male: n = 20, age: 42.75 ± 4.22 yr, the levels of steroids in the patients were normalized to the mean concentration of the controls to exclude gender and menopausal variations. Results Many urinary steroids were up-regulated in all PTC patients compared to the controls. Among them, the levels of three active androgens, androstenedione, androstenediol and 16α-hydroxy DHEA, were significantly higher in the pre-menopausal women and men with PTC. The corticoid levels were increased slightly in the PTC men, while progestins were not altered in the post-menopausal PTC women. Estrogens were up-regulated in all PTC patients but 2-hydroxyestrone and 2-hydroxy-17β-estradiol were remarkably changed in both pre-menopausal women and men with PTC. For both menopausal and gender differences, the 2-hydroxylation, 4-hydroxylation, 2-methoxylation, and 4-methoxylation of estrogens and 16α-hydroxylation of DHEA were differentiated between pre- and post-menopausal PTC women (P P -7. Conclusions These results are expected be helpful for better understanding the pathogenic differences in PTC according to gender and menopausal conditions.

  1. The effect of depressive symptomatology on plasma cortisol responses to acute bicycle exercise among post-menopausal women

    NARCIS (Netherlands)

    van der Pompe, G.; Bernards, N; Meijman, T.F.; Heijnen, C.J

    1999-01-01

    The present study was designed to elucidate the effect of depressive symptomatology on the cortisol response to strenuous exercise. Thirteen healthy, post-menopausal women participated in this study. The results show that acute bicycle exercise activates the hypothalamic-pituitary-adrenal (HPA) axis

  2. Non-hormonal treatment of vulvo-vaginal atrophy-related symptoms in post-menopausal women.

    Science.gov (United States)

    Tersigni, C; Di Simone, N; Tempestilli, E; Cianfrini, F; Russo, R; Moruzzi, M C; Amar, I D; Fiorelli, A; Scambia, G; Villa, P

    2015-01-01

    In post-menopausal period vulvo-vaginal atrophy (VVA)-related symptoms may seriously affect women's quality of life. Hormonal replacement therapy effectively relieves these symptoms but it is not always safe or accepted, and a non-hormonal treatment is often needed instead. Over a period of 12 weeks, we tested the effect of a twice-a-week vulvo-vaginal application of a hyaluronic acid, AC collagen, isoflavones and vitamins-based cream (Perilei Pausa) on 35 women in post-menopausal period, reporting VVA-related symptoms. After 12 weeks of treatment with Perilei Pausa a significant improvement in vaginal dryness, vulvo-vaginal itching, dyspareunia (P < 0.001), dysuria (P = 0.02), nocturia (P = 0.009) and pollakiuria (P = 0.005) was reported by the women. Colposcopical score assessing the intensity of atrophic colpitis, cervico-vaginal paleness and petechiae was also reduced (P = 0.037, P = 0.016 and P = 0.032, respectively). No significant difference in terms of maturation value of cervico-vaginal epithelium was observed. In conclusion, Perilei Pausa may represent an effective and safe alternative treatment of symptomatic VVA in post-menopausal women. PMID:25968636

  3. Mammographic parenchymal texture as an imaging marker of hormonal activity: a comparative study between pre- and post-menopausal women

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    Daye, Dania; Bobo, Ezra; Baumann, Bethany; Ioannou, Antonios; Conant, Emily F.; Maidment, Andrew D. A.; Kontos, Despina

    2011-03-01

    Mammographic parenchymal texture patterns have been shown to be related to breast cancer risk. Yet, little is known about the biological basis underlying this association. Here, we investigate the potential of mammographic parenchymal texture patterns as an inherent phenotypic imaging marker of endogenous hormonal exposure of the breast tissue. Digital mammographic (DM) images in the cranio-caudal (CC) view of the unaffected breast from 138 women diagnosed with unilateral breast cancer were retrospectively analyzed. Menopause status was used as a surrogate marker of endogenous hormonal activity. Retroareolar 2.5cm2 ROIs were segmented from the post-processed DM images using an automated algorithm. Parenchymal texture features of skewness, coarseness, contrast, energy, homogeneity, grey-level spatial correlation, and fractal dimension were computed. Receiver operating characteristic (ROC) curve analysis was performed to evaluate feature classification performance in distinguishing between 72 pre- and 66 post-menopausal women. Logistic regression was performed to assess the independent effect of each texture feature in predicting menopause status. ROC analysis showed that texture features have inherent capacity to distinguish between pre- and post-menopausal statuses (AUC>0.5, pmenarche, ethnicity, contraception use and hormonal replacement therapy (HRT) use lead to a modest model improvement (AUC=0.78) while texture features maintained significant contribution (p<0.05). The observed differences in parenchymal texture features between pre- and post- menopausal women suggest that mammographic texture can potentially serve as a surrogate imaging marker of endogenous hormonal activity.

  4. Residential proximity to major roadways and incident hypertension in post-menopausal women.

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    Kingsley, Samantha L; Eliot, Melissa N; Whitsel, Eric A; Wang, Yi; Coull, Brent A; Hou, Lifang; Margolis, Helene G; Margolis, Karen L; Mu, Lina; Wu, Wen-Chih C; Johnson, Karen C; Allison, Matthew A; Manson, JoAnn E; Eaton, Charles B; Wellenius, Gregory A

    2015-10-01

    Living near major roadways has been associated with increased risk of cardiovascular morbidity and mortality, presumably from exposure to elevated levels of traffic-related air and/or noise pollution. This association may potentially be mediated through increased risk of incident hypertension, but results from prior studies are equivocal. Using Cox proportional hazards models we examined residential proximity to major roadways and incident hypertension among 38,360 participants of the Women's Health Initiative (WHI) Clinical Trial cohorts free of hypertension at enrollment and followed for a median of 7.9 years. Adjusting for participant demographics and lifestyle, trial participation, and markers of individual and neighborhood socioeconomic status, the hazard ratios for incident hypertension were 1.13 (95% CI: 1.00, 1.28), 1.03 (0.95, 1.11), 1.05 (0.99, 1.11), and 1.05 (1.00, 1.10) for participants living ≤50, >50-200, >200-400, and >400-1000 m vs >1000 m from the nearest major roadway, respectively (ptrend=0.013). This association varied substantially by WHI study region with hazard ratios for women living ≤50 m from a major roadway of 1.61 (1.18, 2.20) in the West, 1.51 (1.22, 1.87) in the Northeast, 0.89 (0.70, 1.14) in the South, and 0.94 (0.75, 1.19) in the Midwest. In this large, national cohort of post-menopausal women, residential proximity to major roadways was associated with incident hypertension in selected regions of the U.S. If causal, these results suggest residential proximity to major roadways, as a marker for air, noise and other traffic-related pollution, may be a risk factor for hypertension. PMID:26282224

  5. Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma

    International Nuclear Information System (INIS)

    To evaluate the metabolic changes in urinary steroids in pre- and post-menopausal women and men with papillary thyroid carcinoma (PTC). Quantitative steroid profiling combined with gas chromatography-mass spectrometry was used to measure the urinary concentrations of 84 steroids in both pre- (n = 21, age: 36.95 ± 7.19 yr) and post-menopausal female (n = 19, age: 52.79 ± 7.66 yr), and male (n = 16, age: 41.88 ± 8.48 yr) patients with PTC. After comparing the quantitative data of the patients with their corresponding controls (pre-menopause women: n = 24, age: 33.21 ± 10.48 yr, post-menopause women: n = 16, age: 49.67 ± 8.94 yr, male: n = 20, age: 42.75 ± 4.22 yr), the levels of steroids in the patients were normalized to the mean concentration of the controls to exclude gender and menopausal variations. Many urinary steroids were up-regulated in all PTC patients compared to the controls. Among them, the levels of three active androgens, androstenedione, androstenediol and 16α-hydroxy DHEA, were significantly higher in the pre-menopausal women and men with PTC. The corticoid levels were increased slightly in the PTC men, while progestins were not altered in the post-menopausal PTC women. Estrogens were up-regulated in all PTC patients but 2-hydroxyestrone and 2-hydroxy-17β-estradiol were remarkably changed in both pre-menopausal women and men with PTC. For both menopausal and gender differences, the 2-hydroxylation, 4-hydroxylation, 2-methoxylation, and 4-methoxylation of estrogens and 16α-hydroxylation of DHEA were differentiated between pre- and post-menopausal PTC women (P < 0.001). In particular, the metabolic ratio of 2-hydroxyestrone to 2-hydroxy-17β-estradiol, which could reveal the enzyme activity of 17β-hydroxysteroid dehydrogenase, showed gender differences in PTC patients (P < 1 × 10-7). These results are expected be helpful for better understanding the pathogenic differences in PTC according to gender and menopausal conditions

  6. Association between Soy Isoflavone Intake and Breast Cancer Risk for Pre- and Post-Menopausal Women: A Meta-Analysis of Epidemiological Studies

    OpenAIRE

    Meinan Chen; Yanhua Rao; Yi Zheng; Shiqing Wei; Ye Li; Tong Guo; Ping Yin

    2014-01-01

    BACKGROUND: Conclusions drawn from meta-analyses on the association between soy isoflavone intake and breast cancer risk for pre- and post-menopausal women are not fully consistent. These meta-analyses did not explore the influence of different study designs on the pooled results on the basis of distinguishing between pre- and post-menopausal women. METHODOLOGY AND PRINCIPAL FINDINGS: We performed a meta-analysis of 35 studies which reported results of association between soy isoflavone intak...

  7. Neoadjuvant hormonal therapy is associated with comparable outcomes to neoadjuvant chemotherapy in post-menopausal women with estrogen receptor-positive breast cancer

    OpenAIRE

    Marcus, David M.; Switchenko, Jeffrey M.; Roshan ePrabhu; Ruth eO'Regan; Amelia eZelnak; Carolina eFasola; Donna eMister; Torres, Mylin A.

    2013-01-01

    Objectives: We compared outcomes in post-menopausal estrogen receptor-positive (ER+) breast cancer patients treated with neoadjuvant hormonal therapy (NAHT) or neoadjuvant chemotherapy (NACT).Methods: We retrospectively identified post-menopausal women who received either NAHT or NACT for non-metastatic, non-inflammatory, ER+, Her2neu negative breast cancer from 2004 to 2011. We compared long-term rates of locoregional relapse free survival (LRFS), distant metastasis free survival (DMFS), ...

  8. Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer

    OpenAIRE

    Marcus, David M.; Switchenko, Jeffrey M.; Prabhu, Roshan; O’Regan, Ruth; Zelnak, Amelia; Fasola, Carolina; Mister, Donna; Torres, Mylin A.

    2013-01-01

    Objectives: We compared outcomes in post-menopausal estrogen receptor-positive (ER+) breast cancer patients treated with neoadjuvant hormonal therapy (NAHT) or neoadjuvant chemotherapy (NACT). Methods: We retrospectively identified post-menopausal women who received either NAHT or NACT for non-metastatic, non-inflammatory, ER+, Her2neu negative breast cancer from 2004 to 2011. We compared long-term rates of locoregional relapse free survival (LRFS), distant metastasis free survival (DMFS),...

  9. Pyometra presenting in conjunction with bowel cancer in a post-menopausal women: a case report

    OpenAIRE

    Soleymani majd, Hooman; Watermeyer, Sean; Ismail, Lamiese

    2008-01-01

    This case describes a 71 year old, post-menopausal woman who developed vaginal discharge. This complaint ultimately led to the discovery of bowel cancer in conjunction with a large sterile pyometra. The pyometra was not due to genital malignancy. The most likely conclusion is that the pyometra may have arisen as an inflammatory response to the adjacent bowel pathology. This case report highlights the need for clinicians to consider non-gynaecological cancer as a possible cause for otherwise u...

  10. Concentrations of isoflavones in plasma and urine of post-menopausal women chronically ingesting high quantities of soy isoflavones.

    Science.gov (United States)

    Mathey, J; Lamothe, V; Coxam, V; Potier, M; Sauvant, P; Bennetau-Pelissero, C

    2006-06-01

    Soy food or food supplements based on soy containing isoflavones (Isos) are increasingly available in Western countries. However, the variability of Isos levels in urine and plasma in humans during chronic ingestion is poorly documented. Nevertheless, this is the way these compounds will most probably be used in the future, especially if the soy-based supplements market goes on increasing. Here, glycosilated Isos in an enriched extract of Prevastein equal to 100 mg of equivalent Isos aglycone was given daily to 27 post-menopausal women for 30 days and to 12 post-menopausal women for 60 days. Volunteers were given Prevastein in a cereal bar (25 mg Isos) and in a yoghurt (25 mg Isos) both at breakfast and dinner. Plasma samples were collected after overnight fasting. Urine samples were aliquots of a 24 h collection checked on volume and creatinin excretion levels. Genistein, daidzein and equol were measured at day 0 and every 15 days afterwards, using original specific ELISAs. Constant levels were reached from the 15th day. About 59.2% of the volunteers were significant equol producers in the first experiment and 58.3% in the second. A large variability in plasma and urine levels was observed among post-menopausal women consuming 100 mg Isos per day, although remaining relatively stable in each individual subject. This could partly account for the controversial effects of Isos recorded so far in clinical studies. So Isos plasma levels would have to be assayed during chronic exposures, and could help to better understand the large variability of the effects classically observed in clinical studies. ELISA techniques could be easily exported to analytical laboratories to help physicians and nutritionists with their prescriptions. PMID:16513315

  11. Effect of laser acupuncture combined with a diet-exercise intervention on metabolic syndrome in post-menopausal women

    OpenAIRE

    El-Mekawy, Hanan S.; ElDeeb, Abeer M; Hassan O. Ghareib

    2014-01-01

    This study aimed to evaluate the effect of laser acupuncture combined with a diet-exercise intervention on features of the metabolic syndrome (MetS). Twenty-eight obese post-menopausal women were randomly distributed to the control and laser acupuncture group. The control group received the diet-exercise intervention and the study group received the same intervention and sessions of laser acupuncture, 3 times/week for 12 weeks. Anthropometric measurement, fasting blood glucose and insulin lev...

  12. Treatments for post-menopausal osteoporotic women, what's new? How can we manage long-term treatment?

    Science.gov (United States)

    Herrero, Soledad; Pico, Yolanda

    2016-05-15

    Since the mid-1980s, postmenopausal osteoporosis (PMO) has been considered a serious public health concern because of the associated fractures. Pharmacological therapies that effectively reduce the number of fractures by improving bone mass have been and are being developed continuously. Most current agents inhibit bone loss by reducing bone resorption, but emerging therapies may increase bone mass by stimulating bone formation. Furthermore, nowadays, the most representative pharmaceuticals have been prescribed long enough to include the reporting of some adverse effects. This review discusses osteoporotic drugs that are approved or are under investigation for the treatment of post-menopausal women (PMW), paying particular attention to long-term treatments. PMID:26923729

  13. Diagnostic Efficacy of Panoramic Radiography in Detection of Osteoporosis in Post-Menopausal Women with Low Bone Mineral Density

    Directory of Open Access Journals (Sweden)

    Sunanda Bhatnagar

    2013-01-01

    Full Text Available Objective: The aim of the study was to evaluate panoramic radiograph, a commonly taken dental radiograph as a screening tool to detect early osseous changes (normal, mildly or severely eroded of the mandibular inferior cortex and measure the mandibular cortical width (CW in post-menopausal women and correlate it with the bone mineral density (BMD measured by the ultrasound bone sonometer at the mid-shaft tibia region. Materials and Methods: The study included females between 45 years and 65 years of age in their post-menopausal stage (no menstruation for at least 6-12 months. Mandibular indices (mandibular CW and mandibular cortical shape were evaluated from panoramic radiographs. The BMD assessment was carried out at the mid-shaft tibia region, exactly half-way between the heel and the knee joint perpendicular to the direction of the bone, using an ultrasound bone sonometer. It is a non-invasive device designed for quantitative measurement of the velocity of ultrasound waves as "speed of sound" in m/s, capable of measuring bone density at one or more skeletal sites. Using 1994 WHO criteria the study subjects were categorized as Group 1: Normal, Group 2: Osteopenia, Group 3: Osteoporosis. (WHO T score for tibia BMD can be used as a standard. Results: The diagnostic efficacy of the panoramic radiograph in detecting osseous changes in post-menopausal women with low BMD was shown to have 96% specificity and 60% sensitivity with mandibular cortical shape and 58% specificity and 73% sensitivity with mandibular CW measurement. Factorial ANOVA analysis carried out indicated a significant correlation of BMD classification with mandibular cortical shape (F = 29.0, P < 0.001, partial eta squared [η2 ] =0.85, a non-significant correlation with mandibular CW, (F = 1.6, P = 0.23, η2 = 0.86, and a more significant correlation with combined cortical shape and width (F = 3.3, P < 0.05, η2 = 0.70. Conclusion: The study concludes that the combined mandibular

  14. Alterations in Circulating miRNA Levels following Early-Stage Estrogen Receptor-Positive Breast Cancer Resection in Post-Menopausal Women

    DEFF Research Database (Denmark)

    Kodahl, Annette R; Zeuthen, Pernille; Binder, Harald; Knoop, Ann S; Ditzel, Henrik J

    2014-01-01

    alterations were also observed in an independent data set. METHODS: Global miRNA analysis was performed on prospectively collected serum samples from 24 post-menopausal women with estrogen receptor-positive early-stage breast cancer before surgery and 3 weeks after tumor resection using global LNA...... design and the same qPCR profiling platform, resulting in limited agreement. CONCLUSIONS: A panel of 4 circulating miRNAs exhibited significantly altered levels following radical resection of primary ER+ breast cancers in post-menopausal women. These specific miRNAs may be involved in tumorigenesis and...

  15. The impact of clothing style on bone mineral density among post menopausal women in Morocco: a case-control study

    Directory of Open Access Journals (Sweden)

    Saoud Bouchra

    2006-05-01

    Full Text Available Abstract Background The clothing style is an important factor that influences vitamin D production and thus bone mineral density. We performed a case-control study in order to evaluate the effect of veil wearing (concealing clothing on bone mineral density in Moroccan post menopausal women. Methods The cases were osteoporotic women whose disease was assessed by bone mineral density measurement. Each patient was matched with a non osteoporotic woman for age, and body mass index. All our patients were without secondary causes or medications that might affect bone density. The veil was defined as a concealing clothing which covered most of the body including the arms, the legs and the head. This definition is this of the usual Moroccan traditional clothing style. Results 178 post menopausal osteoporotic patients and 178 controls were studied. The mean age of the cases and the controls was 63.2 years (SD 7 and the mean body mass index was 32.1 (SD 8. The results of crude Odds Ratios analyses indicated that wearing a veil was associated with a high risk of osteoporosis: OR 2.29 (95% CI, 1.38–3.82. Multiparity or a history of familial peripheral osteoporotic fractures had also a significant effect on increasing the osteoporosis risk (ORs: 1.87 (95% CI, 1.05–3.49 and 2.01 (95% CI, 1.20–3.38. After a multiple regression analysis, wearing the veil and a history of familial osteoporotic fractures remained the both independent factors that increased the osteoporosis risk (ORs: 2.20 (95% CI, 1.22–3.9 and 2.19 (95% CI, 1.12–4.29 respectively. Conclusion our study suggested that in Moroccan post menopausal women, wearing a traditional concealing clothing covering arms, legs and head increased the risk of osteoporosis. Further studies are required to evaluate the clinical impact of the above findings and to clarify the status of vitamin D among veiled women in Morocco.

  16. Study on the relationship between serum testosterone level and forearm distal bone density in post-menopausal women

    International Nuclear Information System (INIS)

    Objective: To study the relationship between the androgen level and bone density in post-menopausal women. Methods: Serum testosterone (T) level and forearm distal bone density (BMD) were measured in 39 past-menopausal women who had never taken any estrogen or calcium preparation. Their serum estradiol (E2) levels were about the same. According to their BMD, the 39 subjects were divided into normal (n = 22) and osteoporotic (n = 17) groups. Results: The mean serum testosterone (T) level in the normal group was significantly higher than that in the osteoporotic group (p 1 = 0.72, r20.75; p 1 and r2 was 0.14, suggesting similarity of the positive cor-relationship for both groups (p > 0.05). Conclusion: Serum testosterone level seems to bear close relationship with bone density and osteoporosis

  17. The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women

    Directory of Open Access Journals (Sweden)

    Pullenayegum Eleanor

    2011-09-01

    Full Text Available Abstract Background In the absence of head-to-head trials, indirect comparisons of randomized placebo-controlled trials may provide a viable option to assess relative efficacy. The purpose was to estimate the relative efficacy of reduction of fractures in post-menopausal women, and to assess robustness of the results. Methods A systematic literature review of multiple databases identified randomized placebo-controlled trials with nine drugs for post-menopausal women. Odds ratio and 95% credibility intervals for the rates of hip, non-vertebral, vertebral, and wrist fractures for each drug and between drugs were derived using a Bayesian approach. A drug was ranked as the most efficacious if it had the highest posterior odds ratio, or had the highest effect size. Results 30 studies including 59,209 patients reported fracture rates for nine drugs: alendronate (6 studies, denosumab (1 study, etidronate (8 studies, ibandronate (4 studies, raloxifene (1 study, risedronate (7 studies, strontium (2 study, teriparatide (1 study, and zoledronic acid (1 study. The drugs with the highest probability of reducing non-vertebral fractures was etidronate and teriparatide while the drugs with the highest probability of reducing vertebral, hip or wrist fractures were teriparatide, zoledronic acid and denosumab. The drugs with the largest effect size for vertebral fractures were zoledronic acid, teriparatide and denosumab, while the drugs with the highest effect size for non-vertebral, hip or wrist fractures were alendronate or risedronate. Estimates were consistent between Bayesian and classical approaches. Conclusion Teriparatide, zoledronic acid and denosumab have the highest probabilities of being most efficacious for non-vertebral and vertebral fractures, and having the greatest effect sizes. The estimates from indirect comparisons were robust to differences in methodology.

  18. Whole body retention of Tc-99m Methylene Diphosphonate (MDP) in monitoring skeletal calcium status in post-menopausal women

    International Nuclear Information System (INIS)

    The detection and estimation of skeletal calcium loss has become an important consideration in the management of post-menopausal women. The need to supplement large amounts of calcium of 1000-1500 mg per day is recommended to forestall the risk of skeletal fractures. The added supplementation of estrogens and progesterone for several years is also recommended to prevent bone calcium loss. The need to record the calcium status in post-menopausal women is becoming necessary in the present scenario. A total of 159 women in the peri-menopausal, menopausal and post-menopausal groups were selected. None of them had other systemic diseases. They were healthy and not on any medication. They were randomly grouped into 3 groups. One was considered as control and no medication was advised. The second group was advised 1000-1500 mg of calcium carbonate daily. The third group was given the same dose of calcium, but also received additionally another 2 mg of estradiol daily. Whole Body Retention (WBR) studies of Tc-99m MDP were carried out before starting treatment and at 6 monthly intervals for a period of 5 years. Serum calcium and alkaline phosphatase were estimated on fasting samples at the start of the study and at every 6 monthly intervals. WBR studies were done using a shadow shield whole body counter attached with a 5 inch diameter sodium iodide crystal detector and a 5 mm wide slit collimator. The WBR of Tc-99m MDP at 24 hours was found to be 27.55 ± 6.76% in women in the peri-menopausal age range of 25-45 years. It was also observed that at the time of menopause 13.3% of the women had WBR values above 2 SD of the normal values. This suggests that calcium loss from the skeleton is present only in a small number of women at menopause. However in women who were not supplemented with calcium or subjected to hormonal and calcium treatment, the number of women who showed loss of bone calcium increased within a period of 1-2 years after menopause. This simple method of WBR

  19. The association between breast tissue optical content and mammographic density in pre- and post-menopausal women.

    Directory of Open Access Journals (Sweden)

    Kristina M Blackmore

    Full Text Available Mammographic density (MD, associated with higher water and lower fat content in the breast, is strongly related to breast cancer risk. Optical attenuation spectroscopy (OS is a non-imaging method of evaluating breast tissue composition by red and near-infrared light transmitted through the breast that, unlike mammography, does not involve radiation. OS provides information on wavelength dependent light scattering of tissue and on absorption by water, lipid, oxy-, deoxy-hemoglobin. We propose that OS could be an alternative marker of breast cancer risk and that OS breast tissue measures will be associated with MD. In the present analysis, we developed an algorithm to estimate breast tissue composition and light scattering parameters using a spectrally constrained global fitting procedure employing a diffuse light transport model. OS measurements were obtained from 202 pre- and post-menopausal women with normal mammograms. Percent density (PD and dense area (DA were measured using Cumulus. The association between OS tissue composition and PD and DA was analyzed using linear regression adjusted for body mass index. Among pre-menopausal women, lipid content was significantly inversely associated with square root transformed PD (β = -0.05, p = 0.0002 and DA (β = -0.05, p = 0.019; water content was significantly positively associated with PD (β = 0.06, p = 0.008. Tissue oxygen saturation was marginally inversely associated with PD (β = -0.03, p = 0.057 but significantly inversely associated with DA (β = -0.10, p = 0.002. Among post-menopausal women lipid and water content were significantly associated (negatively and positively, respectively with PD (β lipid = -0.08, β water = 0.14, both p<0.0001 and DA (β lipid = -0.10, p<0.0001; β water = 0.11, p = 0.001. The association between OS breast content and PD and DA is consistent with more proliferation in dense tissue of younger women, greater lipid content in low density tissue and higher water

  20. Responses to concurrent radiotherapy and hormone-therapy and outcome for large breast cancers in post-menopausal women

    International Nuclear Information System (INIS)

    Introduction: This study aimed to evaluate responses and outcome of hormone-therapy (HT) and radiotherapy (RT) given concurrently for large breast cancers in post-menopausal women. Material and methods: Forty-two breast carcinomas in 41 women were treated with HT and concurrent RT to the breast ± lymph node bearing areas. For 30 tumours this was followed by breast surgery (with axillary lymph node dissection when the axilla had not been irradiated). RT delivered a median dose to the tumour of 50 Gy (48-66) and 75 Gy (65-84) for, respectively, preoperative and exclusive RT-HT. Median follow-up was 64 months. Results: Out of 42 clinically assessable tumours (after a mean dose of 50 Gy), 9 tumours (21%) had complete clinical responses, 24 (57%) partial responses, 9 (21%) stable disease. Breast-conserving surgery or exclusive RT-HT was possible in 74% of tumours. For 29 patients who underwent breast surgery, the rate of pathological complete responses was 17%. At 50 Gy no skin toxicity higher than grade 2 occurred. Five year OS, RFS and local control were, respectively, 85%, 84% and 97%. Lymphoedema occurred in one patient. Conclusion: Concurrent association of RT-HT demonstrated good efficacy, both in terms of clinical and pathological complete responses. It allowed breast conservation with acceptable tolerance and good 5-year local control

  1. Effect of laser acupuncture combined with a diet-exercise intervention on metabolic syndrome in post-menopausal women.

    Science.gov (United States)

    El-Mekawy, Hanan S; ElDeeb, Abeer M; Ghareib, Hassan O

    2015-09-01

    This study aimed to evaluate the effect of laser acupuncture combined with a diet-exercise intervention on features of the metabolic syndrome (MetS). Twenty-eight obese post-menopausal women were randomly distributed to the control and laser acupuncture group. The control group received the diet-exercise intervention and the study group received the same intervention and sessions of laser acupuncture, 3 times/week for 12 weeks. Anthropometric measurement, fasting blood glucose and insulin levels, homeostatic model assessment-insulin resistance (HOMA-IR), and lipid profile were assessed before and after the treatment course. Both groups showed a significant decrease in the anthropometric and metabolic parameters. However, laser acupuncture group showed a greater decrease in the waist (P = 0.001) and hip (P = 0.001) circumferences, cholesterol (P = 0.04), and insulin levels (P = 0.043) than the control group. These results suggest that laser acupuncture is a valuable approach that could be added to the diet-exercise intervention to correct features of the MetS. PMID:26425364

  2. Effect of laser acupuncture combined with a diet-exercise intervention on metabolic syndrome in post-menopausal women

    Directory of Open Access Journals (Sweden)

    Hanan S. El-Mekawy

    2015-09-01

    Full Text Available This study aimed to evaluate the effect of laser acupuncture combined with a diet-exercise intervention on features of the metabolic syndrome (MetS. Twenty-eight obese post-menopausal women were randomly distributed to the control and laser acupuncture group. The control group received the diet-exercise intervention and the study group received the same intervention and sessions of laser acupuncture, 3 times/week for 12 weeks. Anthropometric measurement, fasting blood glucose and insulin levels, homeostatic model assessment-insulin resistance (HOMA-IR, and lipid profile were assessed before and after the treatment course. Both groups showed a significant decrease in the anthropometric and metabolic parameters. However, laser acupuncture group showed a greater decrease in the waist (P = 0.001 and hip (P = 0.001 circumferences, cholesterol (P = 0.04, and insulin levels (P = 0.043 than the control group. These results suggest that laser acupuncture is a valuable approach that could be added to the diet-exercise intervention to correct features of the MetS.

  3. Relationship of morningness-eveningness questionnaire score to melatonin and sleep timing, body mass index and atypical depressive symptoms in peri- and post-menopausal women

    OpenAIRE

    Meliska, Charles John; Martínez, Luis Fernando; López, Ana María; Sorenson, Diane Lynn; Nowakowski, Sara; Parry, Barbara Lockhart

    2011-01-01

    Previous work shows a relationship between measures of morning or evening preference (e.g., Morningness-Eveningness Questionnaire (MEQ) scores) and melatonin and sleep timing, body mass index (BMI) and mood. This study explores the relationship of these factors to atypical depression (ATD) symptoms, particularly increased appetite and hypersomnia, in depressed and non-depressed peri- and post-menopausal women. Participants were 19 normal control subjects and 10 depressed patients, 46 – 72 yea...

  4. Associations between bone mineral density and urinary phthalate metabolites among post-menopausal women: a cross-sectional study of NHANES data 2005-2010.

    Science.gov (United States)

    DeFlorio-Barker, Stephanie A; Turyk, Mary E

    2016-06-01

    Bone mineral density (BMD) decreases with age, especially among post-menopausal women. Exposures to endocrine disruptors, such as phthalate diesters, could alter BMD through a variety of unidentified mechanisms. A hypothesis-generating study investigated associations between urinary phthalate metabolites and BMD at the femoral neck and spine in post-menopausal women (n = 480) participating in the National Health and Nutrition Examination Survey, from 2005 to 2010. Mono-ethyl phthalate (MEP), molar sum of low molecular weight metabolites (mono-n-butyl phthalate (MNBP), mono-isobutyl phthalate (MIBP), MEP), molar sum of estrogenic metabolites (MNBP, MIBP, MEP, mono-benzyl phthalate (MBZP)), and an estrogenic equivalency factor were negatively associated with spinal BMD. Some associations were modified by age or BMI. The cross-sectional study design, uncertainty regarding the critical time window of exposure, the potential for exposure misclassification, and residual confounding limit our abilities to draw causal conclusions regarding phthalate metabolites and BMD in post-menopausal women. Future studies should address these limitations. PMID:26586408

  5. Obesity in post menopausal women with a family history of breast cancer: prevalence and risk awareness

    OpenAIRE

    Begum, Parvin; Richardson, Caroline E; Carmichael, Amtul R.

    2009-01-01

    Background: Obesity and physical activity are modifiable risk factors in the development of postmenopausal breast cancer. The aim of this study was to assess the level of awareness and prevalence of these factors in women attending family history clinics. Methods: Women attending the breast cancer family history clinic from 2004 to 2006 completed a questionnaire (SP15 format) about their knowledge of and exposure to various diet and lifestyle factors. All women had been counselled by a Co...

  6. Food matrix and isoflavones bioavailability in early post menopausal women: A European clinical study

    NARCIS (Netherlands)

    Chanteranne, B.; Branca, F.; Kardinaal, A.; Wahala, K.; Braesco, V.; Ladroite, P.; Brouns, F.; Coxam, V.

    2008-01-01

    The estrogenic effects of soy isoflavones (IF) on symptoms of menopause are of particular interest. The aim of the present study was to improve compliance of IF in two IF-enriched foods providing the same IF circulating levels in postmenopausal women. Forty-two healthy postmenopausal women (mean age

  7. Neoadjuvant hormonal therapy is associated with comparable outcomes to neoadjuvant chemotherapy in post-menopausal women with estrogen receptor-positive breast cancer

    Directory of Open Access Journals (Sweden)

    David M. Marcus

    2013-12-01

    Full Text Available Objectives: We compared outcomes in post-menopausal estrogen receptor-positive (ER+ breast cancer patients treated with neoadjuvant hormonal therapy (NAHT or neoadjuvant chemotherapy (NACT.Methods: We retrospectively identified post-menopausal women who received either NAHT or NACT for non-metastatic, non-inflammatory, ER+, Her2neu negative breast cancer from 2004 to 2011. We compared long-term rates of locoregional relapse free survival (LRFS, distant metastasis free survival (DMFS, and overall survival (OS using the Kaplan-Meier method. The Cox proportional hazards model was used to identify patient and disease factors significantly associated with these endpoints. Results: We identified 99 patients in our study, including 27 who received NAHT and 72 who received NACT. There were no differences in 4-year LRFS, DMFS, or OS between groups. On Cox proportional hazards modeling, the type of systemic therapy (NAHT vs. NACT was not associated with OS. However, patients with progesterone receptor (PR positive disease had a 92% lower risk of death compared to patients with PR negative disease.Conclusions: Our data suggest that outcomes are not adversely affected by NAHT in post-menopausal women with ER+ breast cancer. Therefore, NAHT is a viable and potentially less toxic option than NACT in appropriately selected patients. Furthermore, although PR negative disease appears to be associated with poor prognosis, intensification of systemic treatment with chemotherapy may not be associated with improvement of disease-related outcomes in this patient population.

  8. Periodontitis and bone mineral density among pre and post menopausal women: A comparative study

    Directory of Open Access Journals (Sweden)

    Suresh Snophia

    2010-01-01

    Full Text Available Aim: The aim of the study was to assess the relationship between bone mineral density and periodontitis in premenopausal and postmenopausal women. Materials and Methods: Twenty women between the age group of 45-55 years were selected for this study. Ten premenopausal women with healthy periodontium constituted the control group and 10 postmenopausal women with ≥2mm of clinical attachment loss in> 30% of sites constituted the study group. All patients were assessed for plaque index, probing depth and clinical attachment loss. Radiographs (six IOPA and two posterior bitewing were taken and assessed for interproximal alveolar bone loss. The patients were scanned to assess the bone mineral density of lumbar spine (L2 and femur using dual energy X-ray absorptiometry (DEXA. Results: The bone mineral densities of lumbar spine (L2 and femur were significantly lower in the study group than the control group. Osteopenia of the lumbar spine and femur was observed in 60% whereas osteoporosis of lumbar spine was observed in 30% of cases in study group. Conclusion: Increased proportion of osteopenia and osteoporosis cases of lumbar spine and femur in postmenopausal women with periodontitis suggests that there is association between bone mineral density and periodontitis.

  9. Association of morning illumination and window covering with mood and sleep among post-menopausal women

    OpenAIRE

    Youngstedt, Shawn D.; Leung, Amy; Kripke, Daniel F.; Langer, Robert D.

    2004-01-01

    The antidepressant and sleep-promoting effects of light exposure might be useful for treating age-related mood and sleep disorders. In view of recent evidence suggesting beneficial effects of morning light, this study examined the associations of mood and sleep with morning light exposure, 24 h environmental illumination, and the degree to which the volunteers’ bedroom windows were covered in the morning. We examined 459 postmenopausal women participating an ancillary study of the Women’s Hea...

  10. Compliance and treatment satisfaction of post menopausal women treated for osteoporosis. Compliance with osteoporosis treatment

    OpenAIRE

    Huas Dominique; Debiais Françoise; Blotman Francis; Cortet Bernard; Mercier Florence; Rousseaux Chantal; Berger Véronique; Gaudin Anne-Françoise; Cotté François-Emery

    2010-01-01

    Abstract Background Adherence to anti-osteoporosis treatments is poor, exposing treated women to increased fracture risk. Determinants of poor adherence are poorly understood. The study aims to determine physician- and patient- rated treatment compliance with osteoporosis treatments and to evaluate factors influencing compliance. Methods This was an observational, cross-sectional pharmacoepidemiological study with a randomly-selected sample of 420 GPs, 154 rheumatologists and 110 gynaecologis...

  11. Impact of age on aortic wave reflection responses to metaboreflex activation and its relationship with leg lean mass in post-menopausal women.

    Science.gov (United States)

    Figueroa, Arturo; Jaime, Salvador J; Johnson, Sarah A; Alvarez-Alvarado, Stacey; Campbell, Jeremiah C; Feresin, Rafaela G; Elam, Marcus L; Arjmandi, Bahram H

    2015-10-01

    Wave reflection (augmentation pressure [AP] and index [AIx]) is greater in older women than men. Resting AP is a better wave reflection index than AIx in older adults. The negative relationship between wave reflection and lean mass (LM) has been inconsistent. We investigated the impact of age and LM on aortic hemodynamic responses to metaboreflex activation in post-menopausal women. Post-menopausal women, younger and older (n=20 per group) than 60 years, performed 2-min isometric handgrip at 30% of maximal force followed by 3-min post-exercise muscle ischemia (PEMI). We measured carotid-femoral pulse wave velocity (cfPWV) and femoral-ankle PWV (faPWV) at rest, and aortic systolic blood pressure (aSBP), pulse pressure (aPP), AP, AIx, and AIx-adjusted for heart rate (AIx@75) at rest and during PEMI using tonometry. Arm and leg LM were measured by DEXA. Resting cfPWV, aSBP, and aPP were higher, while AIx@75 and leg LM were lower in older than younger women. aSBP and aPP increased similarly during PEMI in both groups. Increases in AP (P<0.05), AIx (P<0.05), and AIx@75 (P<0.01) during PEMI were greater in older than younger women. From these responses, only AP during PEMI was correlated (P<0.05) positively with aSBP and aPP responses, and negatively with leg LM. Resting faPWV, but not cfPWV, was correlated (P<0.01) with AP, aSBP, and aPP during PEMI. Therefore, PEMI induces greater wave reflection responses in older than younger post-menopausal women. Our findings suggest that the increased AP response to PEMI is related to leg arterial stiffness and muscle loss in older women. PMID:26192974

  12. Food matrix and isoflavones bioavailability in early post menopausal women: An European clinical study

    Directory of Open Access Journals (Sweden)

    Brigitte Chanteranne

    2008-11-01

    Full Text Available Brigitte Chanteranne1,2, Francesco Branca3, A Kaardinal4, K Wahala5, Véronique Braesco6, Philippe Ladroite7, Fred Brouns8, Véronique Coxam1,21INRA, Centre Clermont-Ferrand – Theix, UMR1019, Unité Nutrition Humaine, St Genès Champanelle, France; 2Univ Clermont 1, UFR Médecine, UMR1019, Unité Nutrition Humaine, Clermont-Ferrand, France; 3INRAN, Human Nutrition Unit, Ardeatina, Rome, Italy; 4TNO Nutrition and Food Research, Zeist, The Netherlands; 5Department of Chemistry, University of Helsinki, Helsinki, Finland; 6Danone Vitapole, Le Plessis Robinson, France; 7Nutrition Santé, Ravel, France; 8Eridania Beghin Say, Vilvoorde Research and Development Centre, Vilvoorde, BelgiumAbstract: The estrogenic effects of soy isoflavones (IF on symptoms of menopause are of particular interest. The aim of the present study was to improve compliance of IF in two IF-enriched foods providing the same IF circulating levels in postmenopausal women. Forty-two healthy postmenopausal women (mean age: 53.28 years were recruited for a randomized, crossover, multicenter trial conducted in the Netherlands, Italy and France. Over 18 days, volunteers were assigned to two groups and supplemented with two different IF-enriched foods (100 mg IF aglycones/two servings. The first group had to eat two biscuits daily for three days. After a wash-out period (11 d, they received cereal bars for three days. The second group started with the cereal bars and finished with biscuits. After IF intake, plasma and urinary levels of genistein, daidzein, O desmethyl angolensin and equol significantly increased and returned to baseline level after the washout period. There was no difference between biscuits and cereals bars intake, as shown by group values at each end of experimental period (day 4 or day 18. Both matrixes are comparable in terms of IF-circulating levels and could be used independently.Keywords: soy isoflavones, bioavailability, food processing, postmenopausal women

  13. Evaluation of the Association Between Periodontal Parameters Osteoporosis and Osteopenia in Post Menopausal Women

    Directory of Open Access Journals (Sweden)

    Amir Moeintaghavi

    2013-01-01

    Full Text Available Objective: Different studies have reported contradictory results about the effect of osteoporosis on periodontal status. We performed this study to evaluate the periodontal status of menopausal women by methods with enough accuracy and confidence.Materials and Methods: This study was performed based on the evaluation of bone mineral density using dual energy X-ray absorptiometry in 2010. A total of 60 patients who met the inclusion criteria were selected and divided into three groups of osteoporosis, osteopenia, and normal. Then, evaluation of periodontal markers such as pocket depth (DP, attachment loss (AL, and tooth loss (TL was performed by a dental student. A panoramic radiography was performed for those who were suspicious of periodontal disease and bone decline. Finally, evaluation of the periodontal indexes was compared among the three groups using ANOVA with 95% confidence interval.Results: Mean bone decline was higher in the osteoporosis group compared to the other two groups, but the difference was not significant (P=0.065. In addition, mean of plaque index (P=0.123, pocket depth (P=0.856, attachment loss (p=0.525, and tooth loss (p=0.884, the number of people with attachment loss ≥ 2millimeter (P=0.866 and the number of people with alveolar bone loss ≥ 2 millimeter (P=0.348 were not significantly different between the three groups.Conclusion: In this study, no significant difference was observed between the three groups in terms of plaque index, pocket depth, attachment loss, or tooth loss. However, further studies are required that could control all the possible confounding variables.

  14. Association of morning illumination and window covering with mood and sleep among post-menopausal women

    Science.gov (United States)

    YOUNGSTEDT, Shawn D; LEUNG, Amy; KRIPKE, Daniel F; LANGER, Robert D

    2014-01-01

    The antidepressant and sleep-promoting effects of light exposure might be useful for treating age-related mood and sleep disorders. In view of recent evidence suggesting beneficial effects of morning light, this study examined the associations of mood and sleep with morning light exposure, 24 h environmental illumination, and the degree to which the volunteers’ bedroom windows were covered in the morning. We examined 459 postmenopausal women participating an ancillary study of the Women’s Health Initiative conducted at the University of California, San Diego Clinical Center, San Diego, CA, USA. At baseline, volunteers completed a 4-week sleep-recall questionnaire. Volunteers were then assessed for 5–7 days in their home environments with actigraphic wrist monitors. During home recording, self-reported mood was assessed. Morning illumination during the first 4 h after arising, 24-h illumination mesor (cosine-fitted mean), and illumination acrophase (cosine-fitted peak time) were calculated. Sleep was scored each night using validated wrist actigraphic methods. A sleep diary was completed each morning. During two 24-h periods, urine was collected approximately every 2 h during wakefulness and following any voidings during the sleep period. Cosine-fitting established the acrophase of urinary 6-sulfatoxymelatonin (aMT6s) excretion. Morning illumination and 24-h illumination were modestly associated with better mood and sleep. Associations of light with mood and sleep were consistently greater for subjects whose body clocks were delayed relative to the group median. Less morning window covering in the subjects’ bedrooms was associated with more morning light and less depressed mood. The results suggest that both morning and 24-h light exposure may be beneficial for older adults. PMID:25374475

  15. Marine n-3 fatty acid intake, glutathione S-transferase polymorphisms and breast cancer risk in post-menopausal Chinese women in Singapore.

    Science.gov (United States)

    Gago-Dominguez, Manuela; Castelao, J Esteban; Sun, Can-Lan; Van Den Berg, David; Koh, Woon-Puay; Lee, Hin-Peng; Yu, Mimi C

    2004-11-01

    We have previously found marine n-3 fatty acids to be inversely related to post-menopausal breast cancer in Chinese women from Singapore. Post-menopausal women with high [quartiles 2-4 (Q2-Q4)] versus low [quartile 1 (Q1)] intake exhibited a statistically significant reduction in risk of breast cancer after adjustment for potential confounders [relative risk (RR) = 0.66, 95% confidence interval (CI) = 0.50, 0.87]. Experimental studies have demonstrated a direct role for the peroxidation products of marine n-3 fatty acids in breast cancer protection. There is a suggestion that the glutathione S-transferases (GSTs) may be major catalysts in the elimination of these beneficial by-products. Therefore, we hypothesized that individuals possessing the low activity genotypes of GSTM1, GSTT1 and/or GSTP1 (i.e. the GSTM1 null, GSTT1 null and GSTP1 AB/BB genotypes, respectively) may exhibit a stronger marine n-3 fatty acid-breast cancer association than their high activity counterparts. The Singapore Chinese Health Study is a prospective investigation involving 35,298 middle-aged and older women, who were enrolled between April 1993 and December 1998. In this case-control analysis, nested within the Singapore Chinese Health Study, we compared 258 incident breast cancer cases with 670 cohort controls. Overall, breast cancer risk was unrelated to GSTM1 and GSTP1 genotypes. However, the GSTT1 null genotype was associated with a 30% reduced risk of breast cancer [odds ratio (OR) = 0.71, 95% CI = 0.52, 0.96]. Among women with high activity GST genotypes (i.e. GSTM1 positive, GSTT1 positive and GSTP1 AA), no marine n-3 fatty acid-breast cancer relationships were observed in either pre-menopausal or post-menopausal women at baseline. However, post-menopausal women possessing the combined GSTM1 null and GSTP1 AB/BB genotypes showed a statistically significant reduction in risk after adjustment for potential confounders (Q2-Q4 versus Q1, OR = 0.36, 95% CI = 0.14, 0.94). A similar

  16. Effect of Hormone Replacement Therapy on Serum Complement (C3,C4) and Immunoglobulin (IgG, IgM) Levels in Post-menopausal Women

    Institute of Scientific and Technical Information of China (English)

    Yi LIU; Liqun LV

    2008-01-01

    Serum C3, C4, IgG and IgM levels were evaluated in healthy post-menopausal women receiving short-term hormone replacement therapy (HRT) regimens and in untreated women. Serum C3, C4, IgM and IgG levels were assessed in 54 women receiving HRT therapy (CEE 0.625 mg+MPA 2.5 mg/day), and in 54 control women not receiving HRT. The results showed that the mean serum C3 and C4 levels were significantly higher in women receiving HRT than those untreated women (P<0.01). There was significant difference in lgG and IgM levels between two groups. It was con-cluded that HRT might be involved in the development of cardiovascular diseases through inflamma- tory mechanisms, as suggested by increased serum levels of C3 and C4.

  17. Correlating Estrogen Levels and Cognitive Functions in Regularly Menstruating Females of Reproductive Age Group and Post Menopausal Women of North India.

    Directory of Open Access Journals (Sweden)

    Deepti Khattar

    2015-06-01

    Full Text Available To correlate serum estrogen levels with cognitive functions calculated objectively as per Mini Mental State Examination (MMSE in the females in reproductive age group and those attaining menopause.This study was conducted in Christian Medical College and Hospital, Ludhiana, Punjab, India. 150 subjects (100 postmenopausal females and 50 regularly menstruating females of the reproductive age group were included. The cognitive functions of all the females and serum estrogen levels (i.e Estradiol E2 were assessed.The E2 levels in normal menstruating females were found to be higher (mean = 188.062 pg/ml as compared to the menopausal females and the difference in E2 levels was found to be significant (p < 0.001. However, the difference in serum estrogen levels of subjects in the two menopausal groups was insignificant. MMSE, showed that scores of normal menstruating females were higher (mean score = 29.92 as compared to post menopausal females for 1-5 years (mean score = 26.72 and post menopausal females for last 6-10 years (mean score = 26.30.We observed that the cognition functions declined in post menopausal women, whereas the scores were higher in the women of reproductive age group, meaning thereby, that it is the serum estrogen level that is bringing about this difference. Another finding was that the decline in cognition following menopause was not progressive. Therefore, this correlation would open up the gates for the use of estrogen therapy for various neuropsychological disorders pertaining to cognition in the postmenopausal females.

  18. Association of collagen type I alpha1 (COLIA1) Sp1 polymorphism with osteoporotic fracture in Caucasian post-menopausal women: a meta-analysis.

    LENUS (Irish Health Repository)

    Ji, G-R

    2012-01-06

    This study was designed to summarize quantitatively the evidence for a relationship between collagen type I alpha1 (COLIA1) Sp1 polymorphism and osteoporotic fracture risk in Caucasian post-menopausal women. This meta-analysis included 16 studies, which analysed 2294 patients with fractures and 10 285 controls. The combined results showed that there was a significant difference in genotype distribution (SS odds ratio [OR] 0.72; Ss OR 1.18; ss OR 1.97) between patients with fractures and controls. When stratifying by the fracture site, it was found that: (i) patients with vertebral fractures had a significantly higher frequency of the Ss genotype and a lower frequency of the SS genotype than controls; and (ii) patients with non-vertebral fractures had a significantly higher frequency of the ss genotype and a lower frequency of the SS genotype than controls. This meta-analysis suggests that the COLIA1 Sp1 polymorphism may be associated with osteoporotic fracture in Caucasian post-menopausal women.

  19. The immune system during the pre-cancer and the early cancer period. IL-2 production by PBL from post-menopausal women with and without endometrial carcinoma.

    Science.gov (United States)

    Yron, I; Schickler, M; Fisch, B; Pinkas, H; Ovadia, J; Witz, I P

    1986-09-15

    We report on alterations in IL-2 production and cell proliferation following PHA stimulation of peripheral blood lymphocytes (PBL) from stage-I endometrial carcinoma (EC) patients, and on mechanisms involved in these alterations. Our study includes 3 groups: EC patients, post-menopausal women at high risk of developing EC, and age-matched healthy women. IL-2 production was markedly lower in most EC patients than in healthy controls. Varying levels of IL-2 were produced by PBL from women in the high-risk group. The proliferative response of PBL to PHA appeared to correlate with levels of IL-2 production. Our results suggest that macrophages are involved, in part, in the modulation of T-cell functions of EC patients. PMID:3488968

  20. Fatores associados à dislipidemia na pós-menopausa Factors associated with women's dyslipidemia in the post-menopause

    Directory of Open Access Journals (Sweden)

    Ticihana Ribeiro de Oliveira

    2008-12-01

    sample showed to be homogeneous for the socioeconomic characteristics (income, occupation and schooling, physical activity practice, etilism and tabagism, and food ingestion, with no significant correlation with dyslipidemia. The groups presented an income up to two minimal wages, low schooling level (up to the fourth grade of lower school, and the housewife occupation. Smoking and drinking alcohol was not very frequent. Practicing physical activity was non-existent, thus characterizing a sedentary population. Food ingestion was adequate for carbohydrates, protein, lipids, but not for cholesterol (excessive and fibers (insufficient, in both groups. Concerning the anthropometric evaluation, there has been an association with dyslipidemia, as the body mass index (BMI and the waist circumference (WC were significantly larger in case than in control. The waist-hip ratio has been similar in both groups. Weight excess has been found in most of the cases (73.3% as almost half of them (44% presented WC >88 cm, which represents a very increased risk. CONCLUSIONS: it is possible to conclude that, in the studied sample, only the anthropometric measurements have been considered as risk factors associated with dyslipidemia, during post-menopause.

  1. The Effects of Exercising in Different Natural Environments on Psycho-Physiological Outcomes in Post-Menopausal Women: A Simulation Study

    Directory of Open Access Journals (Sweden)

    Mathew P. White

    2015-09-01

    Full Text Available The current study examined potential psycho-physiological benefits from exercising in simulated natural environments among a sample of post-menopausal women using a laboratory based protocol. Participants cycled on a stationary exercise bike for 15 min while facing either a blank wall (Control or while watching one of three videos: Urban (Grey, Countryside (Green, Coast (Blue. Blood pressure, heart rate and affective responses were measured pre-post. Heart rate, affect, perceived exertion and time perception were also measured at 5, 10 and 15 min during exercise. Experience evaluation was measured at the end. Replicating most earlier findings, affective, but not physiological, outcomes were more positive for exercise in the simulated Green and, for the first time, Blue environment, compared to Control. Moreover, only the simulated Blue environment was associated with shorter perceived exercise duration than Control and participants were most willing to repeat exercise in the Blue setting. The current research extended earlier work by exploring the effects of “blue exercise” and by using a demographic with relatively low average levels of physical activity. That this sample of postmenopausal women were most willing to repeat a bout of exercise in a simulated Blue environment may be important for physical activity promotion in this cohort.

  2. Racial and Ethnic Differences in Incident Hospitalized Heart Failure in Post Menopausal Women: The Women’s Health Initiative

    OpenAIRE

    Eaton, CB; Abdulbaki, AM; Margolis, KL; Manson, JE.; Limacher, M; L. Klein; Allison, MA; Robinson, JG; Curb, JD; Martin, LA; Liu, S; Howard, BV

    2012-01-01

    Background-The differences in the incidence of heart failure by race/ethnicity and the potential mechanisms for these differences are largely unexplored in women. Methods and Results-A total of 156 143 postmenopausal women free of self-reported heart failure enrolled from 1993 to 1998 at 40 clinical centers throughout the United States as part of the Women's Health Initiative and were followed up until 2005, for an average of 7.8 years, for incident hospitalized heart failure. Incident rates,...

  3. A comparative study on BMD of lumbar spine and proximal femur in post-menopausal women using dual energy X-ray absorptiometry

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Han Sik [Wonkwang Health Science College, Iksan (Korea, Republic of); Mo, Eun Hee [College of Medicine, Wonkwang Univ., Iksan (Korea, Republic of)

    1999-04-01

    Osteoporosis, which causes mainly fracture of the spine, proximal femur and distal radius by minimal trauma, is a major public health problem and its prevalence is steadily increasing in Korea according to the development of public health care. There are reliable methods for diagnosis based on bone densitometry. Early detection and intervention are important for reducing the incidence of fractures. A consensus definition of osteoporosis, based on bone density measurement, has been developed by the World Health Organization(WHO). In this study, bone mineral density(BMD) was measured by dual energy x-ray absorptiometry(DEXA) at the proximal femur and lumbar spine in 132 post-menopausal women. The purpose of this study is to find influential factors on the BMD of the proximal femur and the lumbar spine and to analyze correlation between BMD and the problematic factors. We obtained the following results : 1. Mean BMD score, T-score and Z-score of the proximal femur were 0.81(g/cm{sup 2}), -2.45(S.D.) and -2.09(S.D.) respectively and in the lumber spine were 0.83(g/cm{sup 2}), -2.02(S.D.), -2.43(S.D.) respectively. 2. In correlation analysis between BMD and many factors, correlation coefficients were -0.467, 0.212, -0.321 and 0.241 in age, height, duration after menopause respectively. BMI and the residuals were comparatively small. 3. Correlation coefficients to age matched BMD, in height and body weight were 0.222 and 0.241, in age and duration after menopause were -0.268, -0.282. 4. The fracture threshold of proximal femur BMD to the 90th percentile was 0.845(g/cm{sup 2}). 5. At the result of multiple regression analysis, age, body weight, BMI(kg/m{sup 2}) and duration after menopause described as significant variables.

  4. The effect of Korean pine nut oil on in vitro CCK release, on appetite sensations and on gut hormones in post-menopausal overweight women

    Directory of Open Access Journals (Sweden)

    Hendriks Henk FJ

    2008-03-01

    Full Text Available Abstract Appetite suppressants may be one strategy in the fight against obesity. This study evaluated whether Korean pine nut free fatty acids (FFA and triglycerides (TG work as an appetite suppressant. Korean pine nut FFA were evaluated in STC-1 cell culture for their ability to increase cholecystokinin (CCK-8 secretion vs. several other dietary fatty acids from Italian stone pine nut fatty acids, oleic acid, linoleic acid, alpha-linolenic acid, and capric acid used as a control. At 50 μM concentration, Korean pine nut FFA produced the greatest amount of CCK-8 release (493 pg/ml relative to the other fatty acids and control (46 pg/ml. A randomized, placebo-controlled, double-blind cross-over trial including 18 overweight post-menopausal women was performed. Subjects received capsules with 3 g Korean pine (Pinus koraiensis nut FFA, 3 g pine nut TG or 3 g placebo (olive oil in combination with a light breakfast. At 0, 30, 60, 90, 120, 180 and 240 minutes the gut hormones cholecystokinin (CCK-8, glucagon like peptide-1 (GLP-1, peptide YY (PYY and ghrelin, and appetite sensations were measured. A wash-out period of one week separated each intervention day. CCK-8 was higher 30 min after pine nut FFA and 60 min after pine nut TG when compared to placebo (p This study suggests that Korean pine nut may work as an appetite suppressant through an increasing effect on satiety hormones and a reduced prospective food intake.

  5. Effects of a Pilates exercise program on muscle strength, postural control and body composition: results from a pilot study in a group of post-menopausal women.

    Science.gov (United States)

    Bergamin, M; Gobbo, S; Bullo, V; Zanotto, T; Vendramin, B; Duregon, F; Cugusi, L; Camozzi, V; Zaccaria, M; Neunhaeuserer, D; Ermolao, A

    2015-12-01

    Participation in exercise programs is heartily recommended for older adults since the level of physical fitness directly influences functional independence. The aim of this present study was to investigate the effects of supervised Pilates exercise training on the physical function, hypothesizing that a period of Pilates exercise training (PET) can increase overall muscle strength, body composition, and balance, during single and dual-task conditions, in a group of post-menopausal women. Twenty-five subjects, aged 59 to 66 years old, were recruited. Eligible participants were assessed prior and after 3 months of PET performed twice per week. Muscular strength was evaluated with handgrip strength (HGS) test, 30-s chair sit-to-stand test (30CST), and abdominal strength (AST) test. Postural control and dual-task performance were measured through a stabilometric platform while dynamic balance with 8 ft up and go test. Finally, body composition was assessed by means of dual-energy X-ray absorptiometry. Statistically significant improvements were detected on HGS (+8.22%), 30CST (+23.41%), 8 ft up and go test (-5.95%), AST (+30.81%), medio-lateral oscillations in open eyes and dual-task condition (-22.03% and -10.37%). Pilates was effective in increasing upper body, lower body, and abdominal muscle strength. No changes on body composition were detected. Results on this investigation indicated also that 12-week of mat Pilates is not sufficient to determine a clinical meaningful improvement on static balance in single and dual-task conditions. PMID:26578458

  6. A comparative study on BMD of lumbar spine and proximal femur in post-menopausal women using dual energy X-ray absorptiometry

    International Nuclear Information System (INIS)

    Osteoporosis, which causes mainly fracture of the spine, proximal femur and distal radius by minimal trauma, is a major public health problem and its prevalence is steadily increasing in Korea according to the development of public health care. There are reliable methods for diagnosis based on bone densitometry. Early detection and intervention are important for reducing the incidence of fractures. A consensus definition of osteoporosis, based on bone density measurement, has been developed by the World Health Organization(WHO). In this study, bone mineral density(BMD) was measured by dual energy x-ray absorptiometry(DEXA) at the proximal femur and lumbar spine in 132 post-menopausal women. The purpose of this study is to find influential factors on the BMD of the proximal femur and the lumbar spine and to analyze correlation between BMD and the problematic factors. We obtained the following results : 1. Mean BMD score, T-score and Z-score of the proximal femur were 0.81(g/cm2), -2.45(S.D.) and -2.09(S.D.) respectively and in the lumber spine were 0.83(g/cm2), -2.02(S.D.), -2.43(S.D.) respectively. 2. In correlation analysis between BMD and many factors, correlation coefficients were -0.467, 0.212, -0.321 and 0.241 in age, height, duration after menopause respectively. BMI and the residuals were comparatively small. 3. Correlation coefficients to age matched BMD, in height and body weight were 0.222 and 0.241, in age and duration after menopause were -0.268, -0.282. 4. The fracture threshold of proximal femur BMD to the 90th percentile was 0.845(g/cm2). 5. At the result of multiple regression analysis, age, body weight, BMI(kg/m2) and duration after menopause described as significant variables

  7. Impact of Tai Chi exercise on multiple fracture-related risk factors in post-menopausal osteopenic women: a pilot pragmatic, randomized trial

    Directory of Open Access Journals (Sweden)

    Wayne Peter M

    2012-01-01

    Full Text Available Abstract Background Tai Chi (TC is a mind-body exercise that shows potential as an effective and safe intervention for preventing fall-related fractures in the elderly. Few randomized trials have simultaneously evaluated TC's potential to reduce bone loss and improve fall-predictive balance parameters in osteopenic women. Methods In a pragmatic randomized trial, 86 post-menopausal osteopenic women, aged 45-70, were recruited from community clinics. Women were assigned to either nine months of TC training plus usual care (UC vs. UC alone. Primary outcomes were changes between baseline and nine months of bone mineral density (BMD of the proximal femur and lumbar spine (dual-energy X-ray absorptiometry and serum markers of bone resorption and formation. Secondary outcomes included quality of life. In a subsample (n = 16, quiet standing fall-predictive sway parameters and clinical balance tests were also assessed. Both intent-to-treat and per-protocol analyses were employed. Results For BMD, no intent-to-treat analyses were statistically significant; however, per protocol analyses (i.e., only including TC participants who completed ≥ 75% training requirements of femoral neck BMD changes were significantly different between TC and UC (+0.04 vs. -0.98%; P = 0.05. Changes in bone formation markers and physical domains of quality of life were also more favorable in per protocol TC vs. UC (P = 0.05. Changes in sway parameters were significantly improved by TC vs. UC (average sway velocity, P = 0.027; anterior-posterior sway range, P = 0.014. Clinical measures of balance and function showed non-significant trends in favor of TC. Conclusions TC training offered through existing community-based programs is a safe, feasible, and promising intervention for reducing multiple fracture risks. Our results affirm the value of a more definitive, longer-term trial of TC for osteopenic women, adequately powered to detect clinically relevant effects of TC on

  8. Diagnostic value of quantitative ultrasound and Osteoporosis self-assessment tool in comparison with DXA in detecting low bone mineral density in post-menopausal women in Riyadh, Kingdom of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    AlJohara M AlQuaiz

    2015-11-01

    Full Text Available The objective of this study was to assess the diagnostic value of quantitative ultrasound (QUS and Osteoporosis self-assessment tool (OST compared with Dual Energy x-ray absorptiometry (DXA, and to identify the best cut-off value for determining low bone mineral density (BMD among postmenopausal women in Riyadh, Saudi Arabia. We conducted a community based cross-sectional study on 224 randomly selected post-menopausal women. Women visited primary heath care centers for answering self-administered questionnaireand screening for low BMD using QUS technique. OST was calculated based on age and weight. DXA scanwas performedforlumbar spine and femur neck at King Khalid University Hospital, Riyadh. Mean age of participants was 58.05(±8.97 years. The prevalence of low BMD at lumbar spine and femur neck was 56% and 28% respectively. The best cut-off value for QUS and OST was ≤-1 and ≤2 respectively. QUS yielded sensitivity and specificity of 73% vs 47% for lumbar spine (area under curve (AUC 0.56 and 84% vs 43% for femur neck (AUC 0.61. OST yielded sensitivity and specificity of 38% vs 84% for lumbar spine (AUC 0.62 and 48% vs 78% for femur neck (AUC 0.68. On combining the results, sensitivity and specificity were81% vs 41% (AUC 0.61 for lumbar spine and 89% vs 35% for femur neck (AUC 0.68 respectively. QUS and OST separately have limited diagnostic value, however on combining both instruments there is improvement in sensitivity to detect low BMD for both lumbar spine and femur neck.

  9. Are cognitive functions in post-menopausal women related with the contents of macro- and micro-components in the diet?

    Directory of Open Access Journals (Sweden)

    Iwona Bojar

    2015-02-01

    Full Text Available [b]The objective[/b] of the study was an evaluation of the relationship between the level of cognitive functions and contents of micro- and macro-components in the diet of postmenopausal women. A group of 402 women was recruited to the study. The inclusion criteria were: minimum two years after the last menstruation, FSH concentration 30 U/ml and no dementia signs on the Montreal Cognitive Assessment (MoCA. A computerized battery of the Central Nervous System Vital Signs (CNS VS test was used to diagnose cognitive functions. The dietary questionnaire was evaluated based on observation of a seven-day diet. The data obtained were introduced into the database and analyzed using computer software DIETICIAN. Statistical analysis was performed using statistical software STATISTICA. [b]Results[/b]. The results of the study concerning diet unequivocally indicate a very poor quality of diet in the group of postmenopausal women examined. The daily diet had a too high energetic value. The women consumed an excessive amount of total fat, including definitely too much monounsaturated fatty acids, and insufficient polyunsaturated fatty acids. The dietary intake of sodium and phosphorus was too high, whereas deficiencies were observed in the consumption of iron, copper, potassium, calcium, magnesium and zinc. No significant correlations were found in the analysis of cognitive functions according to the energetic value of daily diet and contents of macro- and micro-components. The results concerning verbal memory significantly depended on the daily intake of polyunsaturated fatty acids. Women who consumed polyunsaturated fatty acids below the daily normal or normal level obtained significantly higher results in verbal memory.

  10. Temporal changes in clinic and ambulatory blood pressure during cyclic post-menopausal hormone replacement therapy

    DEFF Research Database (Denmark)

    Sørensen, M B; Rasmussen, Verner; Jensen, Gorm Boje; Ottesen, B

    2000-01-01

    OBJECTIVE: Post-menopausal hormone replacement (HRT) might protect against cardiovascular disease, possibly by arterial vasodilation and reduced blood pressure. Progestogens are needed to avoid endometrial disease but vascular effects are controversial. The objective was to assess temporal changes...... in blood pressure (BP) by two measurement techniques during a cyclic hormone replacement regimen. DESIGN AND METHODS: Sixteen healthy and normotensive post-menopausal women (age 55 +/- 3 years) were studied in a placebo-controlled, randomized crossover study, and were randomized to 17beta...

  11. Risk of breast cancer by type of menopausal hormone therapy: a case-control study among post-menopausal women in France.

    Directory of Open Access Journals (Sweden)

    Emilie Cordina-Duverger

    Full Text Available BACKGROUND: There is extensive epidemiological evidence that menopausal hormone therapy (MHT increases breast cancer risk, particularly combinations of estrogen and progestagen (EP. We investigated the effects of the specific formulations and types of therapies used by French women. Progestagen constituents, regimen (continuous or sequential treatment by the progestagen, and time interval between onset of menopause and start of MHT were examined. METHODS: We conducted a population-based case-control study in France in 1555 menopausal women (739 cases and 816 controls. Detailed information on MHT use was obtained during in-person interviews. Odds ratios and 95% confidence interval adjusted for breast cancer risk factors were calculated. RESULTS: We found that breast cancer risk differed by type of progestagen among current users of EP therapies. No increased risk was apparent among EP therapy users treated with natural micronized progesterone. Among users of EP therapy containing a synthetic progestin, the odds ratio was 1.57 (0.99-2.49 for progesterone-derived and 3.35 (1.07-10.4 for testosterone-derived progestagen. Women with continuous regimen were at greater risk than women treated sequentially, but regimen and type of progestagen could not be investigated independently, as almost all EP combinations containing a testosterone-derivative were administered continuously and vice-versa. Tibolone was also associated with an increased risk of breast cancer. Early users of MHT after onset of menopause were at greater risk than users who delayed treatment. CONCLUSION: This study confirms differential effects on breast cancer risk of progestagens and regimens specifically used in France. Formulation of EP therapies containing natural progesterone, frequently prescribed in France, was not associated with increased risk of breast cancer but may poorly protect against endometrial cancer.

  12. Analysis of the Relationship between Estradiol and Follicle-Stimulating Hormone Concentrations and Polymorphisms of Apolipoprotein E and LeptinGenes in Women Post-Menopause

    Science.gov (United States)

    Rył, Aleksandra; Jasiewicz, Andrzej; Grzywacz, Anna; Adler, Grażyna; Skonieczna-Żydecka, Karolina; Rotter, Iwona; Sipak-Szmigiel, Olimpia; Rumianowski, Bogdan; Karakiewicz, Beata; Jurczak, Anna; Parczewski, Miłosz; Urbańska, Anna; Grabowska, Marta; Laszczyńska, Maria

    2016-01-01

    Background: Menopause is the permanent cessation of menstruation due to loss of ovarian follicular activity. A review of the available literature indicates that correlations between the changes that take place in a woman’s body after menopause and different genetic variants are still being sought. Methods: The study was conducted in 252 women who had completed physiological menopause. The women were divided into groups according to the time elapsed since menopause. The total concentrations of estradiol and follicle-stimulating hormone were determined by means of electrochemiluminescence. The apolipoprotein E (APOE) and lepitn (LEP) genotypes were determined by real-time PCR and polymerase chain reaction–restriction fragment length polymorphism, respectively. Results: We observed that people with the APOE3/E3 genotype entered menopause insignificantly later compared to other genotypes. Additionally, in the group of patients with the APOE3/E3 genotypes, differences in the E2 concentration were significantly related to the time since their last menstruation. There is no association found in the literature between these polymorphisms of the LEP gene and hormones. Conclusions: To date, attempts to formulate a model describing the association between E2 and FSH concentration with the polymorphisms of various genes of menopause in women have not been successful. This relationship is difficult to study because of the number of nongenetic factors. Environmental factors can explain variation in postmenopausal changes in hormone levels. PMID:27240396

  13. Metabolismo de repouso de mulheres pós-menopausadas submetidas a programa de treinamento com pesos (hipertrofia Resting metabolism of post-menopause women submitted to a training program with weights (hypertrophy

    Directory of Open Access Journals (Sweden)

    Mara Cléia Trevisan

    2007-04-01

    Full Text Available O estudo objetivou avaliar o gasto energético de repouso (GER de mulheres pós-menopausadas submetidas a programa de treinamento com pesos. Foram estudadas 30 mulheres (FSH > 40mIU/mL entre 45 e 70 anos, separadas em dois grupos (GT: treinamento, n = 15 e GC: controle, n = 15. Calculou-se o índice de massa corporal (kg/m² e por meio da impedância bioelétrica (BIA determinaram-se o percentual de gordura corporal e a massa muscular. O GER foi obtido por meio da calorimetria indireta (O2 e CO2 respiratórios e calculado pela equação de Weir. A mensuração ocorreu após 12 horas de jejum, durante 30 minutos sob temperatura e umidade controladas. O GT participou do programa de treinamento com pesos durante 16 semanas, na freqüência de três vezes por semana. Os dados analisados pelos testes t de Student, Mann-Whitney e ANOVA (p The study had as objective to evaluate the resting energy expenditure (REE of post-menopause women submitted to a training program with weights. Thirty women, age between 45 and 70 years (FSH > 40 mIUmL, separated in two groups (TG: training n = 15 and CG: control n = 15 were studied. The body mass index (kg/m² was calculated and the body fat percentage and the muscular mass were determined through bioelectric impedance (BIA. The REE was obtained through indirect calorimetry (respiratory O2 and CO2 and calculated by the Weir equation. The measurement occurred after 12 hours of fasting, during 30 minutes under controlled temperature and humidity. The TG participated of the training program with weights during 16 weeks, in the frequency of three times per week. The analyzed data by the t-Student, Mann-Whitney and ANOVA tests (p < 0.05 demonstrated that the TG had body mass increased in the 1.8 kg mean, muscular mass in 2.0 kg and the REE presented increase of 8.4% in relation to the CG. In conclusion, the training with weights increased muscular mass and REE. Therefore, this kind of exercise is recommended part of

  14. Quality of life in post-menopausal osteoporosis

    Directory of Open Access Journals (Sweden)

    Ortolani Sergio

    2005-12-01

    Full Text Available Abstract Background To evaluate the impact of osteoporosis on the patients' quality of life, particularly in the absence of fractures. Methods 100 post-menopausal women (age 50-85 - 62 with uncomplicated primary osteoporosis and 38 with primary osteoporosis complicated by vertebral fractures; all already treated - were studied using two validated questionnaires: Qualeffo-41 for quality of life in osteoporosis, and Zung for depression. Data were compared to those of 35 controls of comparable age, affected by a different chronic disease (hypothyroidism. Results Family history of osteoporosis and T-score of spine were similar in the two subgroups of osteoporotic women. Body mass index, age at menopause and education level were similar in the two subgroups of osteoporotic women and in the control group. The patients affected by osteoporosis perceived it as a disease affecting their personal life with undesirable consequences: chronic pain (66% of women with fractures and 40% of women without fractures, impaired physical ability, reduced social activity, poor well-being (21% of women without fractures and depressed mood (42% of women irrespective of fractures. Overall, 41% of the women showed a reduced quality of life. On the contrary, in the control group only 11% reported a reduced quality of life. Conclusion The quality of life of osteoporotic patients should be investigated even before fractures, in order to develop appropriate counselling, support and care interventions to help patients develop efficient strategies for accepting the disease and coping with it.

  15. Vitamin D inadequacy in Belgian postmenopausal osteoporotic women

    Directory of Open Access Journals (Sweden)

    Collette Julien

    2007-04-01

    Full Text Available Abstract Background Inadequate serum vitamin D [25(OHD] concentrations are associated with secondary hyperparathyroidism, increased bone turnover and bone loss, which increase fracture risk. The objective of this study is to assess the prevalence of inadequate serum 25(OHD concentrations in postmenopausal Belgian women. Opinions with regard to the definition of vitamin D deficiency and adequate vitamin D status vary widely and there are no clear international agreements on what constitute adequate concentrations of vitamin D. Methods Assessment of 25-hydroxyvitamin D [25(OHD] and parathyroid hormone was performed in 1195 Belgian postmenopausal women aged over 50 years. Main analysis has been performed in the whole study population and according to the previous use of vitamin D and calcium supplements. Four cut-offs of 25(OHD inadequacy were fixed : Results Mean (SD age of the patients was 76.9 (7.5 years, body mass index was 25.7 (4.5 kg/m2. Concentrations of 25(OHD were 52.5 (21.4 nmol/L. In the whole study population, the prevalence of 25(OHD inadequacy was 91.3 %, 87.5 %, 43.1 % and 15.9% when considering cut-offs of 80, 75, 50 and 30 nmol/L, respectively. Women who used vitamin D supplements, alone or combined with calcium supplements, had higher concentrations of 25(OHD than non-users. Significant inverse correlations were found between age/serum PTH and serum 25(OHD (r = -0.23/r = -0.31 and also between age/serum PTH and femoral neck BMD (r = -0.29/r = -0.15. There is a significant positive relation between age and PTH (r = 0.16, serum 25(OHD and femoral neck BMD (r = 0.07. (P Vitamin D concentrations varied with the season of sampling but did not reach statistical significance (P = 0.09. Conclusion This study points out a high prevalence of vitamin D inadequacy in Belgian postmenopausal osteoporotic women, even among subjects receiving vitamin D supplements.

  16. Temporal changes in clinic and ambulatory blood pressure during cyclic post-menopausal hormone replacement therapy

    DEFF Research Database (Denmark)

    Sørensen, M B; Rasmussen, Verner; Jensen, Gorm Boje;

    2000-01-01

    OBJECTIVE: Post-menopausal hormone replacement (HRT) might protect against cardiovascular disease, possibly by arterial vasodilation and reduced blood pressure. Progestogens are needed to avoid endometrial disease but vascular effects are controversial. The objective was to assess temporal change...... but the reduction varies with the HRT regimen, which might explain the diversity in previous BP findings during HRT. Norethisterone acetate might possess additive blood pressure-lowering effects in postmenopausal women....

  17. A experiência da perimenopausa e pós-menopausa com mulheres que fazem uso ou não da terapia de reposição hormonal Peri-menopausal and post-menopausal experience among women with and without hormone replacement therapy

    Directory of Open Access Journals (Sweden)

    Sônia Maria Garcia Vigeta

    2004-12-01

    Full Text Available Este estudo, uma pesquisa qualitativa, tem por objetivo conhecer o significado da perimenopausa/pós-menopausa e o vivenciar de seus sinais e sintomas para mulheres que usam ou não a terapia de reposição hormonal (TRH. Os dados empíricos foram obtidos por meio de entrevista realizada com 11 mulheres, de 45 a 59 anos de idade, usuárias ou não de TRH e freqüentadoras de diferentes serviços de saúde no Município de São Paulo, Brasil. A análise foi realizada por meio da hermenêutica. Os resultados mais significativos revelam que as mulheres que não fazem uso da TRH apresentam os sintomas da perimenopausa, mas convivem com eles; as mulheres que fazem uso da isoflavona procuram por terapias alternativas para os sintomas que as incomodam; ao passo que as mulheres sob o uso da TRH declaram uma sensação de bem estar. O artigo sugere a importância de capacitar os profissionais da área de saúde para compreenderem que a perimenopausa e a pós-menopausa fazem parte do processo de envelhecimento e, portanto, devem ser consideradas como processo vital e não patológico.This qualitative study focuses on peri-menopausal and post-menopausal experience and its signs and symptoms for women with and without use of hormone replacement therapy (HRT. Empirical data were obtained through interviews with 11 women (range: 45 to 59 years with or without HRT at different health clinics in the Municipality of São Paulo, Brazil. The analysis used the hermeneutic method. Most significantly, women who are not on HRT present peri-menopausal symptoms, but they "live with" such symptoms; meanwhile, women in use of isoflavone rely on alternative therapies for the bothersome symptoms; women using HRT report a feeling of wellbeing. The article suggests the importance of training health professionals to understand the peri-menopausal and post-menopausal periods as part of the aging process, and thus as a vital rather than pathological process.

  18. Oestradiol and sex hormone-binding globulin in premenopausal and post-menopausal meat-eaters, vegetarians and vegans

    OpenAIRE

    Thomas, H V; Davey, G. K.; Key, T.J.

    1999-01-01

    Endogenous oestradiol is strongly associated with breast cancer risk but its determinants are poorly understood. To test the hypothesis that vegetarians have lower plasma oestradiol and higher sex hormone-binding globulin (SHBG) than meat-eaters we assayed samples from 640 premenopausal women (153 meat-eaters, 382 vegetarians, 105 vegans) and 457 post-menopausal women (223 meat-eaters, 196 vegetarians, 38 vegans). Vegetarians and vegans had lower mean body mass indices (BMI) and lower plasma ...

  19. A comparative study of pre- and post-menopausal breast cancer: Risk factors, presentation, characteristics and management

    OpenAIRE

    Surakasula, Aruna; Nagarjunapu, Govardhana Chary; Raghavaiah, K. V.

    2014-01-01

    Objective: Breast cancer is the most common female cancer worldwide and is the second most commonly diagnosed cancer in Indian women. This study evaluates the differences between pre- and post-menopausal breast cancer women regarding risk factors, nature of disease presentation, tumor characteristics, and management. Methods: This is a prospective observational study, conducted in the Oncology Department of St. Ann's Cancer Hospital, for a period of 6 months from January to August 2012. Data ...

  20. Influência da proteína de soja e dos exercícios com pesos sobre o gasto energético de repouso de mulheres na pós-menopausa Influence of soy protein and exercises with weights on the resting energy expenditure of women in post-menopause

    Directory of Open Access Journals (Sweden)

    Mara Cléia Trevisan

    2010-01-01

    Full Text Available OBJETIVO: Analisar a influência da ingestão alimentar de proteína da soja e dos exercícios com pesos sobre o gasto energético de repouso (GER de mulheres na pós-menopausa. MÉTODOS: Ensaio clínico, 16 semanas, envolvendo 60 mulheres, 59 (7 anos, distribuídas em quatro grupos: G1 (proteína da soja e exercício, G2 (placebo e exercício, G3 (proteína da soja e sem exercício e G4 (placebo e sem exercício. A proteína da soja e o placebo (maltodextrina foram distribuídos, aleatoriamente, sob a forma de pó, na porção de 25 gramas/dia. Foram 10 exercícios com pesos, realizados em três sessões semanais, com 3 séries de 8-12 repetições cada, carga de 60%-80% de uma repetição máxima (RM. O GER foi calculado a partir do O2 e CO2, obtidos por calorimetria indireta (Quinton-QMC®, durante 30 minutos, sob temperatura e umidade controladas. Na análise estatística foi utilizada ANOVA, teste T de Student e regressão múltipla, por meio do software Stata 9.2, αOBJECTIVE: The main objective of this study was to analyze the influence of soy protein ingestion and exercises with weights, on resting energy expenditure (REE of women in post-menopause. METHODS: Clinical trial, 16 weeks, involving 60 women, 59 (7 years, distributed in 4 groups: G1 (soy protein and exercise, G2 (placebo and exercise, 3 (soy protein and without exercise and 4 (placebo and without exercise. Randomly, soy protein and placebo (maltodextrin were distributed in powder form, in portions of 25 grams/ day. There were 10 exercises with weights, performed in 3 sessions a week with 3 sets of 8-12 repetitions each, load of 60-80% of 1 maximum repetition (RM. The REE was calculated from the O2 and CO2, obtained through indirect calorimetry (Quinton QMC® for 30 minutes under controlled temperature and humidity. For statistical analysis, ANOVA, Student's t test and multiple regression were used with the software Stata 9.2, α<0.05. RESULTS: Women presented homogeneity in

  1. Expression of COX-2 and MMP-9 in Patients with EMP in Pre-and Post-menopausal Women%COX-2和MMP-9在绝经前后子宫内膜息肉中的表达及其意义

    Institute of Scientific and Technical Information of China (English)

    薛翔; 郭维; 公丕军

    2012-01-01

    Objective To investigate the expression of Cyctooxygenase - 2 ( COX - 2 ) , matrix metalloproteinase- 9( MMP -9) in patients with endometrial polyps( EMP) in pre - and post - menopausal women and their relationship, and to investigate the pathogenesis of EMP. Methods 150 cases with EMP (45 from pre -menopausal women and the other 45 from post - menopausal women) and 60 cases with normal endometrium (30 were proliferative phase endometrium and the other 30 were atrophic endometrium) were collected. Immunohistochemical SP method was used to detect the expression of COX - 2 and MMP - 9 in each tissue. Results 1. In Premenopausal group: Expression of COX - 2 and MMP - 9 in epithelial cells and stroma of EMP were all significantly higher than those in the normal proliferative phase endometrium (P 0. 05 ) . 4. There was a significantly positive correlation between expression of COX -2 and MMP -9(r =0. 6135 ,P < 0.01). Conclusion The expression of COX - 2 is closely associated with MMP -9. Overexpression of COX -2 and MMP -9 in the EMP suggested that COX -2 and MMP -9 may play a role in development of EMP. The pathogenesis of pre - and postmenopausal endometrial polyps may be difference, which may be related to estrogen levels.%目的 研究绝经前、后子宫内膜息肉(EMP)中环氧合酶-2(COX-2)、基质金属蛋白酶-9(MMP-9)的表达及二者的相关性,为研究EMP形成机理提供线索.方法 选取存档石蜡标本共150例,其中绝经前、后EMP各45例,绝经前正常增生期子宫内膜和绝经后正常萎缩型子宫内膜各30例,用免疫组化SP法检测各组COX-2、MMP-9的表达情况,并分析两指标在EMP组织中的表达及相关性.结果 绝经前组COX-2、MMP-9在EMP腺体和间质的表达均显著高于二者在正常增生期子宫内膜中的表达(P<0.05).绝经后组COX-2、MMP-9在EMP间质和腺体中的表达均高于二者在绝经后正常萎缩型子宫内膜中的表达(P<0.05).COX-2在绝经前、后EMP腺体中

  2. Comparison of clinical semi-quantitative assessment of muscle fat infiltration with quantitative assessment using chemical shift-based water/fat separation in MR studies of the calf of post-menopausal women

    Energy Technology Data Exchange (ETDEWEB)

    Alizai, Hamza; Nardo, Lorenzo; Karampinos, Dimitrios C.; Joseph, Gabby B.; Yap, Samuel P.; Baum, Thomas; Krug, Roland; Majumdar, Sharmila; Link, Thomas M. [University of California, San Francisco, Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, San Francisco, CA (United States)

    2012-07-15

    The goal of this study was to compare the semi-quantitative Goutallier classification for fat infiltration with quantitative fat-fraction derived from a magnetic resonance imaging (MRI) chemical shift-based water/fat separation technique. Sixty-two women (age 61 {+-} 6 years), 27 of whom had diabetes, underwent MRI of the calf using a T1-weighted fast spin-echo sequence and a six-echo spoiled gradient-echo sequence at 3 T. Water/fat images and fat fraction maps were reconstructed using the IDEAL algorithm with T2* correction and a multi-peak model for the fat spectrum. Two radiologists scored fat infiltration on the T1-weighted images using the Goutallier classification in six muscle compartments. Spearman correlations between the Goutallier grades and the fat fraction were calculated; in addition, intra-observer and inter-observer agreement were calculated. A significant correlation between the clinical grading and the fat fraction values was found for all muscle compartments (P < 0.0001, R values ranging from 0.79 to 0.88). Goutallier grades 0-4 had a fat fraction ranging from 3.5 to 19%. Intra-observer and inter-observer agreement values of 0.83 and 0.81 were calculated for the semi-quantitative grading. Semi-quantitative grading of intramuscular fat and quantitative fat fraction were significantly correlated and both techniques had excellent reproducibility. However, the clinical grading was found to overestimate muscle fat. (orig.)

  3. Estudo de custo-efetividade do anastrozol adjuvante no câncer de mama em mulheres pós-menopausa Cost-effectiveness analysis of adjuvant anastrozol in post-menopausal women with breast cancer

    Directory of Open Access Journals (Sweden)

    Andre Deeke Sasse

    2009-01-01

    Full Text Available OBJETIVOS: Análise econômica com dados nacionais sobre a possível incorporação do anastrozol como terapia adjuvante hormonal no câncer de mama em pacientes pós-menopausa. MÉTODOS: Foi feita estimativa de custo-efetividade no tratamento adjuvante do câncer de mama, em mulheres pós-menopausa, do anastrozol versus tamoxifeno em três perspectivas: do paciente, de planos de saúde e do governo. Modelo de Markov foi desenvolvido utilizando dados extraídos de publicação do estudo ATAC após seguimento de 100 meses, com projeção de desfechos em 25 anos para uma coorte hipotética de 1000 pacientes com câncer de mama pós-menopausa no Brasil. Dados de utilização de recursos e custos associados foram obtidos de fontes preestabelecidas e de opinião de especialistas. O custo associado aos tratamentos foi extraído separadamente, dependendo do ponto de vista estudado. O benefício foi inserido no modelo para obtenção do custo por ano de vida ganho ajustado pela qualidade (QALY. RESULTADOS: Extrapolando benefícios encontrados para 25 anos de seguimento, o anastrozol, em relação ao tamoxifeno, resultou numa estimativa de ganho de 0,29 QALY. A razão de custo-efetividade por QALY ganho dependeu da perspectiva utilizada. Houve incremento de R$ 32.403,00/QALY no ponto de vista do SUS; de R$ 32.230,00/QALY no dos planos de saúde; e de R$ 55.270,00/QALY no das pacientes. CONCLUSÃO: O benefício encontrado no uso do anastrozol adjuvante em pacientes com câncer de mama operado na pós-menopausa está associado a grandes diferenças na razão de custo-efetividade, dependendo da perspectiva utilizada para o cálculo. Comparando com parâmetros usualmente aceitos pela OMS, o incremento é aceitável sob a perspectiva do SUS e dos planos de saúde, mas não sob a ótica do paciente.OBJECTIVES: Carry out an economic analysis of the incorporation of anastrozole as adjuvant hormone therapy in postmenopausal women with breast cancer in a Brazilian

  4. Hyperandrogenism in post-menopausal women: a diagnosis challenge.

    Science.gov (United States)

    Tutzer, Marta; Winnykamien, Irina; Davila Guardia, Jhery; Castelo-Branco, Camil

    2014-01-01

    A 79-year-old woman, presented with increased hair growth in the chin and the upper lip but no in other androgen-dependent areas of her body. Hormonal evaluation showed markedly elevated serum testosterone level (>1.7 ng/ml) and normal DHEA-S, androstenedione, 17-hydroxyprogesterone, cortisol and TSH levels. The diagnosis of probable pure testosterone secreting tumor was made. Transvaginal ultrasound and magnetic resonance image revealed a 16 mm × 12 mm nodular formation indicative of an atypical adenoma in the left adrenal gland and a tube-shaped, fluid-filled, thin-walled image measuring 28 mm × 14 mm suggestive of a hydrosalpinx in the right ovary. Differential diagnosis between the coexistence of an androgen-producing ovarian tumor (occult) associated with a finding of an adrenal image (Incidentaloma) or an adrenal tumor secreting testosterone only was done. Since cortisol levels went down, but total testosterone inhibition did not occur after suppression with dexamethasone. An ovarian androgen secreting tumour was suspected and surgery was performed. Histological examination showed a Leydig cells hyperplasia. After the operation testosterone returned to normal with regression of clinical symptoms. PMID:24188447

  5. Effect of vaginal estrogen on post menopausal mood & sleep disturbance/ and sexual satisfaction

    Directory of Open Access Journals (Sweden)

    Eftekhar T

    2009-05-01

    Full Text Available "n Normal 0 false false false EN-GB X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Mood disturbances, such as anxiety, depression and psychological distress, are common among women in menopausal period. Effect of long term estrogen replacement on post menopausal  mood disturbances is curative but specifical studies has not done on the effects of vaginal hormonal therapy in mood disturbances in menopause. The aim of this study was objectives to clarify the effect extended by Hormon Replacement Therapy (HRT in improving post menopausal mood disturbances."n"n Methods: In a single blinded clinical trial, the effects of a four months application of vaginal esterogen (premarin versus placebo (n=20 in each groups were evaluated on mood status and sexual satisfaction, using the Hamilton depression score (HDS score, and self assessment of sexual function and pleasure. Four months after treatment completion (half applicator of nightly vaginal premarin or lubricant vaginally collected and analyzed with Statistical tests."n"n Results: Decline of the mean HDS scores (depression score was observed in the premarin group. The mean HDS score (depression after vaginal premarin decreased from (14.6±4.7 to (3.4±2.3. (p≤0.001 also, The HDS score in placebo group increased from (10.6±3.1 to (11±3

  6. A radioimmunoassay for equilin in post-menopausal plasma: plasma levels of equilin determined after oral administration of conjugated equine oestrogens (Premarin)

    International Nuclear Information System (INIS)

    Preparations containing equilin are widely used in hormone therapy at the menopause. No suitable routine assay exists for this steroid. Antisera have been raised to equilin-3-hemisuccinyl-bovine serum albumin, and have been found to be highly specific for equilin. A direct sensitive assay for this steroid in post-menopausal plasma has been established. The implications of the cross-reaction data for the synthesis of oestrogen immunogens are discussed. Equilin has been assayed in samples obtained from oophorectomised women receiving conjugated equine oestrogens (Premarin). (author)

  7. EVALUATION OF THE EFFECTS OF HORMONAL SUBSTITUTION THERAPY UPON THE PERIODONTAL STATUS IN FEMALE PATIENTS DURING PRE- AND POST-MENOPAUSE

    Directory of Open Access Journals (Sweden)

    Irina Ursărescu

    2012-12-01

    Full Text Available Scope of the study. To evaluate the bone mass loss in women, during menopause and post-menopause (a period associated with a deficit of estrogen and the effect of the substitution hormonal therapy. Materials and method. The experimental group included 46 female subjects, evaluated in the beginning of menopause and also at post-menopause, with and without hormonal substitution therapy (in the moment of the consultation. The periodontal clinical (probing depth, CPITN, index of gingival recession, index of dental mobility, index of furcation involvement and radiological indices were evaluated, on following the evolution of the periodontal status from the first consultation in the 3 years. Results. It has been demonstrated that, in patients with periodontitis, early onset menopause and the estrogen deficit, the frequency of gingival bleeding on probing and the clinical loss of attachment were higher, comparatively with the patients having followed a hormonal substitution therapy. Discussion. Apparently, estrogen has a protecting effect upon the periodontium and also upon the severity of the periodontal disease. More than that, the alveolar bone that may be affected by osteoporosis also contributes to the benefic effects of HT, in preventing osteoporosis, the risk of suffering the negative effects of edentation in postmenopause women who receive HT being lower. Conclusions. The present study evidenced the increased incidence of both gingivitis and periodontal pathology, of the ratio of edentation in women at menopause, while the absence of the hormonal substitution therapy seems to be associated with the severity of the periodontal disease.

  8. Steroid cell tumor not otherwise specified of bilateral ovaries: A rare cause of post menopausal virilization

    Directory of Open Access Journals (Sweden)

    Samanthi M. A. Cooray

    2013-01-01

    Full Text Available Steroid cell tumors of the ovaries are rare sex-hormone secreting tumors which are usually benign and unilateral. One previous study has estimated the tumors to be bilateral in 6% of patients. We report a case of post menopausal virilization where tumor histology revealed steroid cell tumor not otherwise specified with benign charactsristics. The presence of tumor in bilateral ovaries made this case unique.

  9. study on the serum levels of E2, IL-6 and IGF-I in patients with post-menopausal osteoporosis (PMO)

    International Nuclear Information System (INIS)

    Objective: To study the changes of serum levels of E2, IL-6, IGF-I in patients with post-menopausal osteoporosis (PMO). Methods: Serum levels of E2(with CLIA), IL-6, IGF-I, BGP (with RIA) were measured in the following subjects: (1) 32 patients with PMO (2) 32 post-menopausal women without PMO and (3) 30 pre-menopausal controls. Serum P, Ca and AKP levels were also determined. Results: As a whole, serum levels of IL -6 in postmenopausal women were higher than those in controls. Levels in subjects with PMO were significantly higher than those without PMO (P2 and BMD index (r=-0. 587, - 0. 438 respectively, P2 and BMD index (r=0.569, 0.433 respectively, P2 levels will in someway promote the expression of IL-6 ( osteoclastic) and reduce the expression of IGF-I (osteoclastic), resulting in lessening of bone mass. HRT, despite of the controversy over cardio-vascalar safety, is beneficial for osteoporosis. (authors)

  10. Scintigraphic examinations during pregnancy and in breast-feeding women: a survey of Belgian nuclear medicine physician's attitudes

    International Nuclear Information System (INIS)

    Radiation protection is of major importance in pregnant and breast feeding women. This work was undertaken to assess the practices of Belgian nuclear medicine physicians towards performing diagnostic tests during pregnancy and in breast feeding women. A questionnaire was sent to 201 Belgian nuclear medicine physicians; 82 answers (41 %) were received. 51 % of the responding physicians agree to perform lung perfusion scan during pregnancy provided a reduced dose is administered, 33% refuse to perform it during first three months and 24% refuse to perform it for pregnancies older than three months. For the Tc-99m ventilation scan 79% and 66% refuse to perform it before and after first three months. Better agreement was observed for other Tc-99m scintigraphies or tests using other radionuclides. In breast feeding women 89% agree to perform Tc-99m tests provided a breast feeding break; however, the duration of this break appears variable. The need for obtaining a written informed consent appears controversial. Given the variability of the attitudes of nuclear medicine physicians, official guidelines for nuclear medicine diagnostic tests during pregnancy is needed. (authors)

  11. Iodine deficiency among Belgian pregnant women not fully corrected by iodine-containing multivitamins: a national cross-sectional survey.

    Science.gov (United States)

    Vandevijvere, Stefanie; Amsalkhir, Sihame; Mourri, Ahmed Bensouda; Van Oyen, Herman; Moreno-Reyes, Rodrigo

    2013-06-28

    Low iodine intake during pregnancy may cause thyroid dysfunction in pregnant women and their newborn. In the present study, iodine status among a nation-wide representative sample of Belgian pregnant women in the first and third trimester of pregnancy was determined, and determinants of iodine status were assessed 1 year after the introduction of bread fortified with iodised salt. The women were selected according to a multistage proportionate-to-size sampling design. Urine samples were collected and a general questionnaire was completed face to face with the study nurse. The median urinary iodine concentration (UIC) among pregnant women (n 1311) was 124.1mg/l and 122.6 mg/g creatinine when corrected for urinary creatinine. The median UIC in the first trimester (118.3 mg/l) was significantly lower than that in the third trimester (131.0 mg/l) but significantly higher than among non-pregnant women (84.8 mg/l). Iodine-containing supplement intake was reported by 60.8% of the women and 57.4% of the women took this supplement daily. The risk of iodine deficiency was significantly higher in younger women, in women not taking iodine-containing supplements, with low consumption of milk and dairy drinks and during autumn. Women with a higher BMI had a higher risk of iodine deficiency but the risk was lower in women who reported alcohol consumption. The median UIC during pregnancy indicates iodine deficiency in Belgium and some women are at a higher risk of deficiency. The current low iodine intake in women of childbearing age precludes the correction of iodine deficiency in pregnant women supplemented with multivitamins containing 150 mg iodine as recommended. PMID:23084115

  12. Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

    DEFF Research Database (Denmark)

    Jørgensen, Niklas Rye; Husted, Lise Bjerre; Skarratt, Kristen K; Stokes, Leanne; Tofteng, Charlotte L.; Kvist, Torben; Jensen, Jens-Erik Beck; Eiken, Pia Agnete; Brixen, Kim; Fuller, Stephen; Clifton-Bligh, Rory; Gartland, Alison; Schwarz, Peter; Langdahl, Bente Lomholt; Wiley, James S

    2012-01-01

    , vertebral fracture incidence was documented at 10 years. We found that the rate of bone loss was clearly associated with the Arg307Gln amino acid substitution such that individuals heterozygous for this polymorphism had a 40% increased rate of bone loss. Furthermore, individuals carrying the Ile568Asn...... variant allele had increased bone loss. In contrast, the Gln460Arg polymorphism was associated with protection against bone loss. The Ala348Thr polymorphism was associated with a lower vertebral fracture incidence 10 years after menopause. Finally, we developed a risk model, which integrated P2RX7...... to bone mass and fracture incidence in post-menopausal women. A total of 1694 women (aged 45-58) participating in the Danish Osteoporosis Prevention Study were genotyped for 12 functional P2X7 receptor variants. Bone mineral density was determined at baseline and after 10 years. In addition...

  13. Relationship of endometrial thickness detected by transvaginal sonography with the results of endometrial biopsy & hysteroscopic directed biopsy in post menopausal bleeding

    Directory of Open Access Journals (Sweden)

    Vahid Dastjerdi M

    2008-05-01

    Full Text Available Background: Post-menopausal hemorrhage is one of the most common complains in gynecologic clinics. More than 60% of these cases have abnormal findings in diagnostic work ups. There is contraversy about the best diagnostic method for evaluating post-menopausal hemorrhage. The aim of this study was to evaluate the results of Trans-Vaginal Ultrasonography and compare its result to ones derived from direct endometrial biopsy and Hysteroscopy findings.Methods: In a cross-sectional study, menopausal women who attended the outpatient clinic of Arash Hospital, Tehran University of medical Sciences, from April 2005 to March 2006 with the complain of hemorrhage were evaluated. In all of these patients, after getting informed consent, Trans-Vaginal Ultrasonography, Dilatation and Curettage and Hysteroscopy were performed.Results: The total number of 90 women was recruited to the study with the age range of 41-80 years. The mean age of participants was 53.84 ± 6 years and 4.3 ± 5.1 years had passed from their menopause. The mean thickness of endometrium, measured by Trans Vaginal ultrasonography was 6.25 ± 3.7 millimeter. In the biopsy derived specimens, the most finding pathological presentation was atrophy (48.9% and the Proliferative endometrium had the second prevalence (36.7%. Atrophy (44.4% and Proliferative endometrium (33.3% were the most prevalent finding in Hysteroscopy. There was a significant difference in endometrial thickness between groups of different pathological findings. A significant difference in endometrial thickness was also seen between groups with different Hysteroscopic finding. By grouping the data according to endometrial thickness, it became evident that endometrial thickness can predict the outcome of endometrial biopsy and Hysteroscopic finding efficiently. We used ROC curves to find the best grouping threshold for endometrial thickness to achieve the best sensitivity and specificity.Conclusion: Measuring the endometrial

  14. Correlation between absence of bone remodeling compartment canopies, reversal phase arrest, and deficient bone formation in post-menopausal osteoporosis

    DEFF Research Database (Denmark)

    Andersen, Thomas L; Hauge, Ellen M; Rolighed, Lars; Bollerslev, Jens; Kjærsgaard-Andersen, Per; Delaisse, Jean-Marie

    2014-01-01

    bone surface from the marrow cavity. The present study on human iliac crest biopsy specimens reveals that BRC canopies appear frequently absent above both eroded and formative surfaces in post-menopausal osteoporosis patients, and that this absence was associated with bone loss in these patients. The...... surfaces was associated with a shift in the osteoblast morphological characteristics, from cuboidal to flattened. Collectively, this study shows that the BRCs are unique anatomical structures implicated in bone remodeling in a widespread disease, such as post-menopausal osteoporosis. Furthermore, it...

  15. Asymptomatic giant struma ovarii in a post-menopausal female:a case report%发生在绝经妇女的无症状巨大卵巢甲状腺肿瘤一例报道

    Institute of Scientific and Technical Information of China (English)

    Dong Xia; Qing Liu; Hui Yao; Jianwei Li; Liang Xu

    2013-01-01

    Struma ovarii, a rare varity of ovarian neoplasm, belongs to the group of monodermic teratomas mainly composed of thyroid tissue. The preoperative diagnosis is always difficult to identify without histopathological examination. Surgery is the only treatment because malignant alteration is possible and thyroid hyperactivity or hyperthyroidism may occur. Our patient, a post-menopausal women, had unilateral, large, multiloculated ovary mass of 20 cm × 15 cm × 10 cm size without any thyroid hyper activity. The radical excision of the tumor with right ovary was preformed. Histopathological examination confirmed struma ovarii. The post-operative period was uneventful and her thyroid function remained normal.

  16. Abdominal Wall Metastasis of Uterine Papillary Serous Carcinoma in a Post-Menopausal Woman: A Case Report

    OpenAIRE

    Park, Jung-Woo; Hwang, Sung-Ook

    2014-01-01

    Uterine papillary serous carcinoma (UPSC) is an aggressive form of endometrial cancer characterized by a high recurrence rate and poor prognosis. We report a case of a 58-year-old post-menopausal woman with an abdominal wall metastasis in stage IA UPSC. After surgical staging, she did not receive additional adjuvant therapy. An egg sized palpable mass developed in the right lower abdomen after 8 months. Both Abdominopelvic computed tomography (CT) and positron emission tomography (PET)-CT rev...

  17. Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery

    Science.gov (United States)

    2015-09-02

    Ductal Breast Carcinoma In Situ; Estrogen Receptor Negative; Estrogen Receptor Positive; HER2/Neu Negative; Invasive Cribriform Breast Carcinoma; Invasive Ductal Carcinoma, Not Otherwise Specified; Lobular Breast Carcinoma In Situ; Mucinous Breast Carcinoma; Papillary Breast Carcinoma; Progesterone Receptor Positive; Stage I Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIC Breast Cancer; Tubular Breast Carcinoma

  18. The effects of red clover on quality of life in post-menopausal women

    OpenAIRE

    Ehsanpour, Soheila; Salehi, Kobra; Zolfaghari, Behzad; Bakhtiari, Soheila

    2012-01-01

    Background: Due to symptoms and its complications, menopause influences the mental, psychological and physical health, social performance and familial relationships. Because of the undesirable side effects of hormone replacement therapy, tendency and desire toward alternative treatments in relieving menopausal symptoms have increased. Among the alternative therapies are herbs and among those, herbs with phytoestrogens are more preferable. Red clover is a rich source of phytoestrogens. The pre...

  19. Study about xerostomia, salivary flow rate and systemic conditions of postmenopausal women

    OpenAIRE

    Flávia Lopes Carvalho; Luciana Freitas Gomes e Silva; Fernanda Ferreira Lopes; Ana Emília Figueiredo de Oliveira

    2008-01-01

    Objective: To make a quantitative evaluation of salivary flow and occurrence of xerostomia in post-menopausal women, according to thesystemic condition related by the patients. Methods: The sample was composed of 20 post-menopausal women, who were submitted to anamnesis and completely stimulated sialometry. Results: The results revealed that 50% of the women examined related the presence of xerostomia; hyposalivation was more present than normal salivary flow and low salivary flow; among the ...

  20. Abdominal wall metastasis of uterine papillary serous carcinoma in a post-menopausal woman: a case report.

    Science.gov (United States)

    Park, Jung-Woo; Hwang, Sung-Ook

    2014-04-01

    Uterine papillary serous carcinoma (UPSC) is an aggressive form of endometrial cancer characterized by a high recurrence rate and poor prognosis. We report a case of a 58-year-old post-menopausal woman with an abdominal wall metastasis in stage IA UPSC. After surgical staging, she did not receive additional adjuvant therapy. An egg sized palpable mass developed in the right lower abdomen after 8 months. Both Abdominopelvic computed tomography (CT) and positron emission tomography (PET)-CT revealed a metastatic lesion in the abdominal wall. Hence, surgical excision was performed. The pathological findings showed metastatic UPSC with clear resection margin. After the diagnosis of UPSC metastasis in the abdominal wall, she received chemotherapy utilizing paclitaxel and carboplatin. After 3 years, no evidence of recurrence was found. Therefore, we suggest that even when UPSC is confined to the endometrium without lymph node metastasis and without lymphovascular invasion, chemotherapy should be considered as a postoperative adjuvant therapy. PMID:25371890

  1. Effect of yoga therapy on reaction time, biochemical parameters and wellness score of peri and post-menopausal diabetic patients

    Directory of Open Access Journals (Sweden)

    Madanmohan

    2012-01-01

    Discussion : Shortening of RT implies an improvement in the information processing and reflexes and is the first such report in diabetic patients. This has clinical significance and is worth further exploration with wider, well controlled, randomized studies in the diabetic population. Changes in blood glucose levels may be due to improved insulin sensitivity, decline in insulin resistance and increased sensitivity of the pancreatic b cells to glucose signals. Yoga improved the ′heart friendly′ status of lipid profile in our subjects and as our participants were peri and post-menopausal, the decrease in cardiovascular risk profile is of greater significance. A comprehensive yoga therapy program has the potential to enhance the beneficial effects of standard medical management of diabetes mellitus and can be used as an effective complementary or integrative therapy program.

  2. Cost-effectiveness of diagnostic strategies for the management of abnormal uterine bleeding (heavy menstrual bleeding and post-menopausal bleeding): a decision analysis.

    Science.gov (United States)

    Cooper, Natalie A M; Barton, Pelham M; Breijer, Maria; Caffrey, Orla; Opmeer, Brent C; Timmermans, Anne; Mol, Ben W J; Khan, Khalid S; Clark, T Justin

    2014-01-01

    BACKGROUND Heavy menstrual bleeding (HMB) and post-menopausal bleeding (PMB) together constitute the commonest gynaecological presentation in secondary care and impose substantial demands on health service resources. Accurate diagnosis is of key importance to realising effective treatment, reducing morbidity and, in the case of PMB, reducing mortality. There are many tests available, including transvaginal scan (TVS), endometrial biopsy (EBx), saline infusion sonography and outpatient hysteroscopy (OPH); however, optimal diagnostic work-up is unclear. OBJECTIVES To determine the most cost-effective diagnostic testing strategy for the diagnosis and treatment of (i) HMB and (ii) PMB. DATA SOURCES Parameter inputs were derived from systematic quantitative reviews, individual patient data (IPD) from existing data sets and focused searches for specific data. In the absence of data estimates, the consensus view of an expert clinical panel was obtained. METHODS Two clinically informed decision-analytic models were constructed to reflect current service provision for the diagnostic work-up of women presenting with HMB and PMB. The model-based economic evaluation took the form of a cost-effectiveness analysis from the perspective of the NHS in a contemporary, 'one-stop' secondary care clinical setting, where all indicated testing modalities would be available during a single visit. RESULTS Two potentially cost-effective testing strategies for the initial investigation of women with HMB were identified: OPH alone or in combination with EBx. Although a combination testing strategy of OPH + EBx was marginally more effective, the incremental cost-effectiveness ratio (ICER) was approximately £21,000 to gain one more satisfied patient, whereas for OPH it was just £360 when compared with treatment with the levonorgestrel intrauterine system (LNG-IUS) without investigation. Initial testing with OPH was the most cost-effective testing approach for women wishing to preserve

  3. Alternative methods for the treatment of post-menopausal troubles [Alternative Methoden zur Behandlung postmenopausaler Beschwerden

    OpenAIRE

    Wasem, Jürgen; Aidelsburger, Pamela; Schauer, Svenja; Grabein, Kristin

    2012-01-01

    Background Menopause is described as the transition from the reproductive phase of a women to the non reproductive. Changes in hormone levels might lead to complaints and health consequences especially during peri- and postmenopause. Hormone therapy has a potential damaging health risk profile and is recommended for temporal limited therapy for acute vasomotor symptoms only. Objective The present HTA-report aims to assess the effectiveness and the cost-effectiveness of alternative treatment m...

  4. High Vitamin C Intake with High Serum β-Cryptoxanthin Associated with Lower Risk for Osteoporosis in Post-Menopausal Japanese Female Subjects: Mikkabi Cohort Study.

    Science.gov (United States)

    Sugiura, Minoru; Nakamura, Mieko; Ogawa, Kazunori; Ikoma, Yoshinori; Yano, Masamichi

    2016-01-01

    Recent epidemiological studies show that antioxidant vitamins and carotenoids might be beneficial to the maintenance of bone health. Recently, we found that serum carotenoids were inversely associated with the risk of developing osteoporosis in post-menopausal Japanese female subjects. However, little is known about the vitamin alone and/or the combination of the vitamin and carotenoid with the risk of osteoporosis. The objective of this study was to investigate longitudinally whether antioxidant vitamins and their combination with carotenoids are associated with the risk of developing of osteoporosis. We conducted a follow-up study on 187 post-menopausal female subjects from the Mikkabi prospective cohort study. Those who participated in previous bone mineral density (BMD) surveys and completed four years of follow-up were examined longitudinally. During a four-year follow-up, fifteen of the post-menopausal female subjects developed new-onset osteoporosis. After adjustment for confounders, the odds ratios (OR) for osteoporosis in the highest tertiles of vitamins C and E and retinol intakes against the lowest tertiles were 0.15 (95% confidence interval (CI): 0.02-0.99), 0.50 (CI: 0.08-3.23), and 1.49 (CI: 0.36-6.22), respectively. Furthermore, a significantly lower odds ratio was observed in the higher vitamin C intake group (169-625 mg/d) with higher serum β-cryptoxanthin (1.88-10.53 μM) against the lower vitamin C intake group (47-168 mg/d) with lower serum β-cryptoxanthin (0.24-1.84 μM) used for the reference group (p<0.05). The combination of β-cryptoxanthin and vitamin C is inversely associated with the risk of developing osteoporosis in post-menopausal Japanese female subjects. PMID:27465725

  5. Study on reproductive endocrinological function in postmenopausal women treated with estriol

    International Nuclear Information System (INIS)

    Objective: To investigate the reproductive endocrinological function in postmenopausal women treated with ultralente estriol for 3 years. Methods: Serum levels of six reproductive hormones (FSH, LH, PRL, T, E2, P) were measured with RIA in 1) 136 normal 1-5yrs post-menopausal women 2) 48 post-menopausal women treated with estriol for 3 years 3) 131 healthy women of child-bearing age during follicular and luteal phases. Results: Serum levels of the six reproductive hormones in women of child-bearing age at both follicular and luteal phases were significantly different from those in post-menopausal women (p 2, P and T levels were not significant (p > 0.05). Conclusion: Serum reproductive hormones assay is important for monitoring hormone replacement therapy in aging women

  6. Symptomatic ovarian steroid cell tumor not otherwise specified in a post-menopausal woman

    Directory of Open Access Journals (Sweden)

    Neha Sood

    2016-06-01

    Full Text Available Steroid cell tumor not otherwise specified (NOS is a rare subtype of sex cord stromal tumor of the ovary and contributes less than 0.1% of all ovarian neoplasms. The majority of tumors occur in pre-menopausal women (mean age: 43 years, in which 56-77% of patients present with virilization due to excess testosterone. An 80-year-old woman with worsening alopecia and excessive growth of coarse hair on abdomen and genital area was found to have elevated serum testosterone level (462 ng/mL. Radiologic studies were consistent with bilateral adrenal adenomas. Bilateral adrenal venous sampling ruled out the adrenal gland as origin of hormone secretion. A diagnostic and therapeutic bilateral salpingooophorectomy confirmed steroid cell tumor NOS of the left ovary. Post-operatively, the patient had complete resolution of her symptoms and normalization of testosterone level. Our case emphasizes the importance of a clinical suspicion for an occult testosterone secreting ovarian tumor in a symptomatic patient without obvious ovarian mass on imaging.

  7. Symptomatic Ovarian Steroid Cell Tumor not Otherwise Specified in a Post-Menopausal Woman.

    Science.gov (United States)

    Sood, Neha; Desai, Kaniksha; Chindris, Ana-Maria; Lewis, Jason; Dinh, Tri A

    2016-06-28

    Steroid cell tumor not otherwise specified (NOS) is a rare subtype of sex cord stromal tumor of the ovary and contributes less than 0.1% of all ovarian neoplasms. The majority of tumors occur in pre-menopausal women (mean age: 43 years), in which 56-77% of patients present with virilization due to excess testosterone. An 80-year-old woman with worsening alopecia and excessive growth of coarse hair on abdomen and genital area was found to have elevated serum testosterone level (462 ng/mL). Radiologic studies were consistent with bilateral adrenal adenomas. Bilateral adrenal venous sampling ruled out the adrenal gland as origin of hormone secretion. A diagnostic and therapeutic bilateral salpingo-oophorectomy confirmed steroid cell tumor NOS of the left ovary. Post-operatively, the patient had complete resolution of her symptoms and normalization of testosterone level. Our case emphasizes the importance of a clinical suspicion for an occult testosterone secreting ovarian tumor in a symptomatic patient without obvious ovarian mass on imaging. PMID:27441075

  8. Alternative methods for the treatment of post-menopausal troubles [Alternative Methoden zur Behandlung postmenopausaler Beschwerden

    Directory of Open Access Journals (Sweden)

    Wasem, Jürgen

    2012-05-01

    Full Text Available [english] Menopause is described as the transition from the reproductive phase of a women to the non reproductive. Changes in hormone levels might lead to complaints and health consequences especially during peri- and postmenopause. Hormone therapy has a potential damaging health risk profile and is recommended for temporal limited therapy for acute vasomotor symptoms only.The present HTA-report aims to assess the effectiveness and the cost-effectiveness of alternative treatment methods for women with postmenopausal symptoms in Germany regarding patient relevant endpoints (reduction of symptoms and frequency of adverse events and improvement of quality of life.A systematic literature search was carried out in 33 relevant databases in September 2010. Citations were selected according to pre-defined criteria and were extracted and evaluated.In the systematic research 22 studies are identified for the effectiveness evaluation, 22 primary studies and one review.High doses of isolated genistein reduce the frequency/intensity of hot flashes while low doses of genistein show no significant effect. Intake of isoflavone extract such as genistein, daidzein, glycitein in various combinations does not have an effect on improvement of cognitive function or vaginal dryness. The effect of black cohosh and hop extract for menopausal complaints cannot be determined since results are heterogenous. The combination of isoflavone, black cohosh, monk’s pepper, valerian and vitamin E has a positive effect on menopause symptoms. Ginkgo biloba shows no significant effect on menopause symptoms and cognitive improvement beside mental flexibility. Acupuncture has a significant influence on hot flashes especially in severe cases.No final statement can be drawn regarding the effectiveness of alter­ne treatment methods due to qualitative shortcomings of included studies and a general limited availability of studies in this field. Furthermore, the generalization of the

  9. Voices from the Hilo Women's Health Study: Talking Story About Menopause

    OpenAIRE

    Morrison, Lynn A.; Sievert, Lynnette L.; Brown, Daniel E; Reza, Angela; Rahberg, Nichole; Mills, Phoebe; Goodloe, Amber

    2013-01-01

    Our purpose in conducting this qualitative study was to examine how a multi-ethnic sample of women living in Hilo, Hawaii describe menopause. Interviews were conducted with 185 pre-, peri-, and post-menopausal women aged 45 to 55. We found that pre-menopausal women felt anxious compared to peri- and post-menopausal women's more affirmative attitudes of increasing confidence and freedom in this new cycle of life. A dominant theme was the construction of a post-menstrual identity. Peri-and post...

  10. Study about xerostomia, salivary flow rate and systemic conditions of postmenopausal women

    Directory of Open Access Journals (Sweden)

    Flávia Lopes Carvalho

    2008-01-01

    Full Text Available Objective: To make a quantitative evaluation of salivary flow and occurrence of xerostomia in post-menopausal women, according to thesystemic condition related by the patients. Methods: The sample was composed of 20 post-menopausal women, who were submitted to anamnesis and completely stimulated sialometry. Results: The results revealed that 50% of the women examined related the presence of xerostomia; hyposalivation was more present than normal salivary flow and low salivary flow; among the patients who related having systemic ailments, cardiovascular diseases were the most frequent, followed by depression and nervousness. Conclusion: It was concluded that xerostomia and quantitative alteration in salivary flow are common among post-menopausal women, and that ailments of a psychological nature were shown to be related to the manifestation of xerostomia.

  11. Belgian Firms Visit CERN

    CERN Multimedia

    2001-01-01

    Fifteen Belgian firms visited CERN last 2 and 3 April to present their know-how. Industrial sectors ranging from precision machining to electrical engineering and electronics were represented. And for the first time, companies from the Flemish and Brussels regions of the country joined their Walloon compatriots, who have come to CERN before. The visit was organised by Mr J.-M. Warêgne, economic and commercial attaché at the Belgian permanent mission for the French-speaking region, Mr J. Van de Vondel, his opposite number for the Flemish region, and Mrs E. Solowianiuk, economic and commercial counsellor at the Belgian permanent mission for the Brussels-Capital region.

  12. Association of CYP2D6 and CYP2C19 polymorphisms and disease-free survival of Thai post-menopausal breast cancer patients who received adjuvant tamoxifen

    Directory of Open Access Journals (Sweden)

    Chamnanphon M

    2013-05-01

    .90%, and *36 (1 of 114, 0.90%; the CYP2C19 variant alleles were *2 (27 of 114, 23.70% and *3 (6 of 114, 5.30%. Kaplan–Meier estimates showed significantly shorter disease-free survival in patients with homozygous TT when compared to those with heterozygous CT or homozygous CC at nucleotides 100C>T and 1039C>T (CYP2D6*10 post-menopausal (log-rank test; P = 0.046. They also had increased risk of recurrence, but no statistically significant association was observed (hazard ratio 3.48; 95% confidence interval 0.86–14.07; P = 0.080.Conclusion: The CYP2D6 and CYP2C19 polymorphisms were not involved in tamoxifen efficacy. However, in the subgroup of post-menopausal women, the polymorphisms in CYP2D6 and CYP2C19 might be useful in predicting tamoxifen efficacy and clinical outcomes in breast cancer patients receiving adjuvant tamoxifen treatment. As the number of breast cancer patients was relatively small in this study, results should be confirmed in a larger group of prospective patients.Keywords: CYP2D6, CYP2C19, disease-free survival, tamoxifen, pharmacogenetics, breast cancer

  13. Study on the therapeutic effect of small dose of estradiol and progesterone on post-menopausal osteoporosis

    International Nuclear Information System (INIS)

    Objective: To explore the therapeutic effect and possible adverse side-effects of small dose of estradiol and progesterone on postmenopausal osteoporosis. Methods: Applying a GBD-928 mono-photon BMD radiometer, 68 women (past-menopausal over 3 years, age 52-59, body weight index 2 0.5 mg with MPA (medroxyprogesterone acetate) 0.5 mg daily. The medication laster for a whole years and BMD value was measured again. All subjects underwent gynecological physical examination, vaginal sonography, vaginal smear study and breast examination with infra-red ray both before and after the test period. Results: After one year medication, mean value of BMD in Group A was 0.49 ± 0.05, three percentage points higher than before. In Group B, this was 0.52 ± 0.06, another three percentage points higher. Ten Women with mild lobular hyperplasia and nine women with small uterine myoma (3) were all allocated to the hormone treated group. The lesions showed either little change or slight regression after the test period. Conclusion: Osteoporotic women receiving additional small doses of female hormones responded much better than those receiving calcium only. The WHI report which advised against HRT should be more critically studied

  14. The impact of vitamin D status on changes in bone mineral density during treatment with bisphosphonates and after discontinuation following long-term use in post-menopausal osteoporosis

    Directory of Open Access Journals (Sweden)

    Fogelman Ignac

    2007-01-01

    Full Text Available Abstract Background It is still unclear whether addition of calcium/vitamin D supplements leads to an incremental benefit in patients taking bisphosphonates and whether achievement of serum level of 25 (OH vitamin D of at least 70 nmol/L has an impact on the skeletal response to bisphosphonates. Moreover the maintenance of BMD after bisphosphonates withdrawal with the continuation of calcium/vitamin D supplements only, remains uncertain. The aims were to assess the impact of vitamin D status on changes in bone mineral density (BMD in firstly patients with post-menopausal osteoporosis on bisphosphonates and secondly following discontinuation of bisphosphonates after long-term use. Methods Two patient groups were recruited. The first study population comprised of 112 women treated with a bisphosphonate. The second study population consisted of 35 women who had been on bisphosphonates for > 5 years in whom the treatment agent was discontinued. Baseline BMD, changes in BMD following treatment, duration of treatment, serum 25 (OH vitamin D, parathyroid hormone (PTH, urine C-terminal telopeptides of type 1 collagen (CTX were obtained on the study participants. Results In the first study group, subjects with serum vitamin D concentrations (> 70 nmol/L had a significantly lower serum PTH level (mean [SEM] 41 2 ng/L. PTH concentrations of 41 ng/L or less was associated with a significantly higher increase in BMD at the hip following treatment with bisphosphonates compared to patients with PTH > 41 ng/L (2.5% [0.9] v/s -0.2% [0.9], P = 0.04. In the second study group, discontinuation of bisphosphonate for 15 months after long-term treatment did not result in significant bone loss at the lumbar spine and total hip, although a trend towards gradual decline in BMD at the femoral neck was observed. Conclusion the data suggest that optimal serum 25 (OH vitamin D concentration may lead to further reduction in bone loss at the hip in patients on bisphosphonates

  15. Effects of beer, wine and liquor intakes on bone mineral density in older adult men and women

    Science.gov (United States)

    Moderate intake of alcohol has been reported to have beneficial effects on bone. However, different classes of alcoholic beverages have not been investigated. We examined alcohol intake (total and individual types) and BMD in 1251 men, 1317 post-menopausal and 264 pre-menopausal women in the populat...

  16. Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia

    OpenAIRE

    Shang, Yu; Gurley, Katelyn; Symons, Brock; Long, Douglas; Srikuea, Ratchakrit; Crofford., Leslie J.; Peterson, Charlotte A.; Yu, Guoqiang

    2012-01-01

    Introduction Women with fibromyalgia (FM) have symptoms of increased muscular fatigue and reduced exercise tolerance, which may be associated with alterations in muscle microcirculation and oxygen metabolism. This study used near-infrared diffuse optical spectroscopies to noninvasively evaluate muscle blood flow, blood oxygenation and oxygen metabolism during leg fatiguing exercise and during arm arterial cuff occlusion in post-menopausal women with and without FM. Methods Fourteen women with...

  17. Is candidiasis the true cause of vulvovaginal irritation in women with diabetes mellitus?

    OpenAIRE

    Rowe, B. R.; Logan, M N; Farrell, I; Barnett, A H

    1990-01-01

    Vulvovaginitis is common in diabetic women and is often treated with antifungal agents on the assumption that the causative organism is Candida albicans. In a survey of 100 consecutive diabetic women attending a diabetes clinic 36 had complained to their general practitioner about vulvovaginal irritation during the past three years and 26 were treated with antifungal agents without a vaginal examination or swabs being taken. In a separate study 27 post-menopausal women with non-insulin depend...

  18. The uterine choriocarcinoma in postmenopausal women: specificities of diagnosis and treatment

    OpenAIRE

    Kaabia, Ons; Meddeb, Sawsen; Rhim, Mohamed Salah; Bibi, Mohamed; Khairi, Hedi

    2014-01-01

    Choriocarcinoma is a gestational trophoblastic tumor that mainly affects women of childbearing age. Cases of choriocarcinoma in postmenopausal women are exceptional. Through an observation and literature review, we propose to study the specific diagnosis and treatment features of this tumor in menopausal women. We report the observation of a pure uterine choriocarcinoma, which occurred in post-menopause. The diagnosis was made on the analysis of surgical specimens confirmed by measurement of ...

  19. Open Access to the Belgian Nuclear higher Education Network

    International Nuclear Information System (INIS)

    Under the name of the Belgian Nuclear higher Education Network, five Belgian universities, Universite Catholique de Louvain, Universiteit Gent, Universite de Liege, Vrije Universiteit Brussel have established in 2002, in collaboration with the Belgian Nuclear Research Centre SCK-CEN, a common Belgian Interuniversity Programme of the third cycle leading to the academic degree of Master of Science in Nuclear Engineering. Under the lead of the SCK-CEN a project to use and share the acquired experience of the Consortium BNEN - in order to support the realization of a common European Education Programme in Nuclear Engineering - has been accepted by the European Commission for funding under the EU's Sixth Research Framework Programme.The project wants to contribute actively to the development of a more harmonised approach for education in nuclear sciences and engineering in Europe. It brings the European higher Education Area closer to realization and helps to safeguard the necessary competence and expertise for the continued safe use of nuclear energy and other uses of radiation in industry and medicine in Europe. The project foresees input and participation from stakeholders from different countries of the enlarged European Union (EU-25) and will therefore contribute to the integration of the new member states into the European Research Area and thus to the enlargement of Europe. The set-up of the project foresees an active role for female experts with the intention to reinforce the place and role of women in science

  20. Increased calcium absorption from synthetic stable amorphous calcium carbonate: Double-blind randomized crossover clinical trial in post-menopausal women

    Science.gov (United States)

    Calcium supplementation is a widely recognized strategy for achieving adequate calcium intake. We designed this blinded, randomized, crossover interventional trial to compare the bioavailability of a new stable synthetic amorphous calcium carbonate (ACC) with that of crystalline calcium carbonate (C...

  1. Vascular and Nutrigenomic effects of a long-term grapefruit juice consumption: a controlled randomized cross-over study in post-menopausal women

    OpenAIRE

    Habauzit, Veronique; Milenkovic, Dragan; Verny, Marie-Anne; Boby, Céline; Mazur, André; Dubray, Claude; Morand, Christine

    2013-01-01

    The consumption of some flavonoid rich foods has been shown to induce improvements in several intermediate markers of cardiovascular risk. Citrus fruits constitute a food source rich in a particular class of flavonoids, that of flavanones. Based on recent epidemiological data as well as on a large number of pre-clinical studies, citrus flavanones may exhibit interesting cardioprotective properties. However clinical evidences accounting for a benefit in consuming dietary flavanones to improve ...

  2. Cytokines and T-lymphocyte subsets in healthy post-menopausal women: estrogen retards bone loss without affecting the release of IL-1 or IL-1ra

    DEFF Research Database (Denmark)

    Abrahamsen, Bo; Bendtzen, Klaus; Beck-Nielsen, H

    1997-01-01

    flow cytometry. One group received cyclic estrogen-gestagen replacement therapy (ERT) while the other group was untreated. In spite of a significant bone maintaining effect of ERT, the basal and LPS-stimulated secretion of IL-1 alpha, IL-1 beta, and IL-1ra was identical in the two groups. There was no...

  3. The effect of Korean pine nut oil on in vitro CCK release, on appetite sensations and on gut hormones in post-menopausal overweight women

    NARCIS (Netherlands)

    Pasman, W.J.; Heimerikx, J.; Rubingh, C.M.; Berg, R. van den; O'Shea, M.; Gambelli, L.; Hendriks, H.F.J.; Einerhand, A.W.C.; Scott, C.; Keizer, H.G.; Mennen, L.I.

    2008-01-01

    Appetite suppressants may be one strategy in the fight against obesity. This study evaluated whether Korean pine nut free fatty acids (FFA) and triglycerides (TG) work as an appetite suppressant. Korean pine nut FFA were evaluated in STC-1 cell culture for their ability to increase cholecystokinin (

  4. Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

    DEFF Research Database (Denmark)

    Gartland, Alison; Skarratt, Kristen K; Hocking, Lynne J;

    2012-01-01

    The P2X7 receptor gene (P2RX7) is highly polymorphic with five previously described loss-of-function (LOF) single-nucleotide polymorphisms (SNP; c.151+1G>T, c.946G>A, c.1096C>G, c.1513A>C and c.1729T>A) and one gain-of-function SNP (c.489C>T). The purpose of this study was to determine whether th...

  5. Scintigraphic examinations during pregnancy and in breast-feeding women: a survey of Belgian nuclear medicine physician's attitudes; Examens scintigraphiques durant la grossesse et chez les femmes en periode d'allaitement: enquete a propos des attitudes pratiques des nuclearistes belges

    Energy Technology Data Exchange (ETDEWEB)

    Tondeur, M.; Ham, H. [Centre Hospitalier Universitaire Saint Pierre, Bruxellex (Belgium); Sand, A. [CEDRI, Vilvoorde (Belgium)

    2003-05-01

    Radiation protection is of major importance in pregnant and breast feeding women. This work was undertaken to assess the practices of Belgian nuclear medicine physicians towards performing diagnostic tests during pregnancy and in breast feeding women. A questionnaire was sent to 201 Belgian nuclear medicine physicians; 82 answers (41 %) were received. 51 % of the responding physicians agree to perform lung perfusion scan during pregnancy provided a reduced dose is administered, 33% refuse to perform it during first three months and 24% refuse to perform it for pregnancies older than three months. For the Tc-99m ventilation scan 79% and 66% refuse to perform it before and after first three months. Better agreement was observed for other Tc-99m scintigraphies or tests using other radionuclides. In breast feeding women 89% agree to perform Tc-99m tests provided a breast feeding break; however, the duration of this break appears variable. The need for obtaining a written informed consent appears controversial. Given the variability of the attitudes of nuclear medicine physicians, official guidelines for nuclear medicine diagnostic tests during pregnancy is needed. (authors)

  6. Diagnostic efficacy of panoramic mandibular index to identify postmenopausal women with low bone mineral densities

    OpenAIRE

    Devi, B.K. Yashoda; Rakesh, Nagaraju; Ravleen, Nagi

    2011-01-01

    Objectives: The aim of the study was to compare and assess the accuracy of panoramic mandibular index (PMI) and antegonial index (AI) in the panoramic radiographs of postmenopausal women with normal and low skeletal bone mineral densities( BMD) diagnosed by using dual energy x-ray absorptiometry ( DXA). Study Design: In panoramic radiographs obtained from 40 post menopausal women( 20 normal and 20 osteoporo tic) aged between 50-75 who’s BMD has already been assessed by...

  7. Depression after low-energy fracture in older women predicts future falls: a prospective observational study

    OpenAIRE

    van den Berg Martha; Verdijk Noortje A; Leusink Geraline L; Wijnands-van Gent Colette JM; Romeijnders Arnold C; Pop Victor JM; van den Bergh Joop PW

    2011-01-01

    Abstract Background Falls are one of the main causes of fractures in elderly people and after a recent fracture, the risk of another fall is increased, resulting in subsequent fracture. Therefore, risk factors for future falls should be determined. We prospectively investigated the relationship between depression and the incidence of falls in post-menopausal women after a low-energy fracture. Methods At baseline, 181 women aged 60 years and older who presented with a recent low-energy fractur...

  8. MOLIERE PROJECT - Belgian National Report

    OpenAIRE

    Naedenoen, Frédéric

    2014-01-01

    This document aims at introducing the restructuring phenomena in Belgium. It makes part of a larger project (called the MOLIERE project) undertaken by eleven European countries gathered to analyse restructurings. This national document follows a common reporting format: an introduction of the complex Belgian restructuring frameworks (1), a presentation of the main actors involved in the process (2), a synthesis of the measures created to anticipate change (3) and a synthesis of the measures ...

  9. A mulher coronariopata no climatério após a menopausa: implicações na qualidade de vida The post menopausal climacteric woman with coronary artery disease: implications to quality of life

    Directory of Open Access Journals (Sweden)

    M.E.C. DE S. FAVARATO

    2001-12-01

    Full Text Available OBJETIVOS: Avaliar a qualidade de vida em mulheres com doença isquêmica do coração no climatério após a menopausa. MÉTODOS: O estudo incluiu 100 mulheres após a menopausa, sendo 50 portadoras de doença arterial coronária (DAC em seguimento no Instituto do Coração (InCor HC-FMUSP e 50 que não apresentavam doenças associadas (grupo controle atendidas no Centro de Saúde Escola Geraldo de Paula Souza da FSP - USP. A qualidade de vida foi avaliada mediante a utilização de dois instrumentos: uma entrevista estruturada e a aplicação do questionário genérico de avaliação de qualidade de vida ( SF - 36 . RESULTADOS: Os grupos eram homogêneos em relação à idade da última menstruação: 49 ±3,9 anos na DAC e 49,2±3 anos no grupo controle. Os grupos também eram similares quanto à escolaridade: 84% possuíam primeiro grau (completo ou incompleto; estado civil: casadas 64% das DAC e 45% do grupo controle e viúvas 18% da DAC e 24% das controle. A atividade profissional fora do lar foi significativamente mais freqüente no grupo controle (52% e 14% nas DAC (p=0,0001. Ambos os grupos demonstraram percepções semelhantes no que se refere à sexualidade. A avaliação da qualidade de vida pelo SF - 36 mostrou melhores resultados no grupo controle em relação a: capacidade física (84 vs 50,5 na DAC; aspectos físicos (84 vs 45,5; estado geral de saúde (87,2 vs 59,1; vitalidade (69,7 vs 51,4 e escore total dos componentes mentais (70,4 vs 58,6. CONCLUSÃO: A coronariopatia interfere na qualidade de vida das mulheres após a menopausa, limitando a capacidade física e o desempenho das atividades da vida diária, além de intensificar as dificuldades emocionais desse período.PURPOSE: To analyse the quality of life of post menopausal women with coronary artery disease. METHODS: The population consisted of 100 women, divided into 2 groups. The firstgroup made up of 50 women whose average age was 58 ± 4,2 years with > stable

  10. Predictors of physical activity at 12 month follow-up after a supervised exercise intervention in postmenopausal women

    OpenAIRE

    Aparicio-Ting, Fabiola E; Farris, Megan; Courneya, Kerry S.; Schiller, Ashley; Friedenreich, Christine M.

    2015-01-01

    Background Few studies have examined recreational physical activity (RPA) after participating in a structured exercise intervention. More specifically, little is known about the long-term effects of exercise interventions in post-menopausal women. This study had two objectives: 1) To compare RPA in postmenopausal women in the exercise group and the control group 12 months after the end of the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial; and 2) To apply the Theory of P...

  11. A Belgian Approach to Learning Disabilities.

    Science.gov (United States)

    Hayes, Cheryl W.

    The paper reviews Belgian philosophy toward the education of learning disabled students and cites the differences between American behaviorally-oriented theory and Belgian emphasis on identifying the underlying causes of the disability. Academic methods observed in Belgium (including psychodrama and perceptual motor training) are discussed and are…

  12. Thyroid dysfunction in perimenopausal and postmenopausal women.

    Science.gov (United States)

    Pearce, Elizabeth N

    2007-03-01

    Thyroid dysfunction is common, especially among women over the age of 50. In caring for peri- and post-menopausal women, it is important to recognize the changing clinical manifestations of thyroid disease with age. Postmenopausal women are at increased risk of both osteoporosis and cardiovascular disease, and untreated thyroid disease may exacerbate these risks. Screening for thyroid dysfunction in asymptomatic individuals is controversial, but aggressive case-finding should be pursued, especially in older women. Women with overt thyroid dysfunction should be treated. Therapy for women with subclinical thyroid dysfunction is more controversial, although women with levels of thyroid stimulating hormone (TSH) > or =10 mU/L should be treated, and treatment may be considered in symptomatic women with subclinical hypothyroidism and TSH values hyperthyroidism who have TSH values consistently hyperthyroidism or hypothyroidism. Finally, caution is required in diagnosing and treating thyroid dysfunction in women who are taking oral estrogens or selective estrogen receptor modulators. PMID:17448261

  13. Prevalence of Calcified Carotid Artery on Panoramic Radiographs in Postmenopausal Women

    OpenAIRE

    Taheri, Jamileh Beigom; Moshfeghi, Mahkameh

    2009-01-01

    Background and aims This study was designed to evaluate the prevalence of calcified carotid artery in 50 year-old and older postmenopausal dental outpatients for early diagnosis of individuals at risk of stroke. Materials and methods This is a descriptive study of 200 panoramic radiographs. These radiographs included post-menopausal women referring to the Department of Oral Medicine at Shahid Beheshti Faculty of Dentistry during 2006-2007. The x-ray machine, developer and film type were the s...

  14. Changes in Vascular Hemodynamics in Older Women Following 16 Weeks of Combined Aerobic and Resistance Training

    OpenAIRE

    Corrick, Katie L.; Hunter, Gary R.; Fisher, Gordon; Glasser, Stephen P.

    2012-01-01

    The purpose of this study was to determine if combined (aerobic and anaerobic) training decreases blood pressure (BP) and improves vascular properties. Seventy-nine post-menopausal women were randomly assigned to three groups that trained at different frequencies. VO2max, body composition, BP, and arterial elasticity were evaluated prior to training and after 16 weeks of training. There was a significant time effect (decrease) for resting systolic blood pressure (SBP) and rate pressure produc...

  15. The Belgian nuclear research centre

    International Nuclear Information System (INIS)

    The Belgian Nuclear Research Centre is almost exclusively devoted to nuclear R and D and services and is able to generate 50% of its resources (out of 75 million Euro) by contract work and services. The main areas of research include nuclear reactor safety, radioactive waste management, radiation protection and safeguards. The high flux reactor BR2 is extensively used to test fuel and structural materials. PWR-plant BR3 is devoted to the scientific analysis of decommissioning problems. The Centre has a strong programme on the applications of radioisotopes and radiation in medicine and industry. The centre has plans to develop an accelerator driven spallation neutron source for various applications. It has initiated programmes to disseminate correct information on issues of nuclear energy production and non-energy nuclear applications to different target groups. It has strong linkages with the IAEA, OECD-NEA and the Euratom. (author)

  16. Integrated modelling of the Belgian coastal zone

    OpenAIRE

    Delhez, E. J. M.; Carabin, G.

    2001-01-01

    The management of the water resources in coastal or delta plains asks for an integrated modelling of the water system at a regional scale. In the SALMON project, detailed descriptions of the groundwater, river and marine domains are provided by coupling appropriate numerical models of these different sub-systems.The application of this three-fold model to the Scheldt and Belgian Coastal Zone reveals a marked river plume extending along the Belgian Coast with strong offshore gradients. This pl...

  17. An ecosystem approach towards Belgian coastal policy

    OpenAIRE

    Vanden Eede, S.

    2013-01-01

    The Belgian coastal zone hosts a complex of space-use and resource-use activities with a myriad of pressures impairing environmental conditions both on the coastline and on coastal waters Specifically at the beach zone, predictions on sea level rise, intensified storms accelerated erosion and flood risk for the North Sea have led to the drafting of the Belgian Integrated Coastal Safety Plan. The preferred coastal defence measure is beach nourishment as it safeguards the natural dynamics of th...

  18. Strategic groups in the Belgian fishing fleet

    OpenAIRE

    Stouten, H.; A. HEENE; Gellynck, X.; Polet, H

    2011-01-01

    This study examines the heterogeneity of the Belgian fishing fleet based on “strategic groups”, a concept borrowed from the field of strategic management. Its objectives are: (1) to define strategic groups within the Belgian fishing fleet; (2) to examine the performance differences among these strategic groups; (3) to examine whether firms (i.e., vessels) move between strategic groups over time; and (4) to examine if firm-movement (i.e., vessel-movement) differs across strategic groups. In th...

  19. Benefits of Estrogen Replacement for Skeletal Muscle Mass and Function in Post-Menopausal Females: Evidence from Human and Animal Studies

    OpenAIRE

    Tiidus, Peter M.

    2011-01-01

    Age related loss of skeletal muscle mass and strength accelerates with the onset of menopause in women. Recent evidence from human and animal studies provides compelling evidence for the role of estrogen based hormone replacement therapy (HRT) in maintaining and enhancing muscle mass and strength and protecting against muscle damage. The physiological mechanisms by which estrogen can positively influence skeletal muscle mass and strength and protect against post-damage inflammation and disrup...

  20. Fatores associados à qualidade de vida após menopausa Factors related to quality of life in post-menopause

    Directory of Open Access Journals (Sweden)

    Dino Roberto Soares De Lorenzi

    2006-10-01

    Full Text Available OBJETIVO: Avaliar a qualidade de vida de mulheres na pós-menopausa. MÉTODOS: Estudo transversal de 323 mulheres pós-menopáusicas com idade entre 45 e 60 anos atendidas em um serviço universitário de atenção ao climatério entre junho e outubro de 2002. A qualidade de vida foi avaliada através do Women's Health Questionnaire. Na análise estatística, utilizou-se o teste t de Student e a análise de variância, seguidos de regressão linear múltipla. RESULTADOS: A qualidade de vida se mostrou comprometida entre a população estudada, em especial nos domínios relacionados a sintomas somáticos, humor deprimido e ansiedade. Por meio de análise multivariada, constatou-se que quanto menor a escolaridade (pOBJECTIVE: To assess quality of life of postmenopausal women. METHODS: A cross-section study of 323 women between 45 and 60 years of age attended at a university climacteric clinic from June to October 2002was carried out. Quality of life was assessed by the Women's Health Questionnaire (WHQ. Statistical analysis was performed with Student's t Test and analysis of variance, followed by multiple linear regression analysis. RESULTS: This study found quality of life impaired especially in the domains related to somatic symptoms, depressed mood, and anxiety. Multivariate analysis showed that lower educational level (p<0.01, frequency of sexual activity (p<0.01 and the confirmation of previous clinical co-morbidities (p=0.03 were associated to the worst scores of quality of life. On the other hand, regular physical activity was related to better quality of life (p=0.01. Hormone therapy, in particular, was not related to quality of life (p=0.48. CONCLUSION: Quality of life was found not only to be influenced by biological factors, but also by psychossocial and cultural factors. Middle aged women frequently attributed eventual symptoms associated to clinical co-morbidities or previous emotional difficulties to menopause, distorting their

  1. Association between the polymorphisms of angiotensin converting enzyme (Peptidyl-Dipeptidase A INDEL mutation (I/D and Angiotensin II type I receptor (A1166C and breast cancer among post menopausal Egyptian females

    Directory of Open Access Journals (Sweden)

    Rania Mohamed El Sharkawy

    2014-09-01

    Results: A statistically significant difference in AT1R A1166C SNP genotype frequencies was found among the studied groups. The patients group showed higher frequency of “CC” (2.9% vs 0% and “AC” (44.3% vs 24% and lower frequency of “AA” genotype (52.9% vs 76% than controls. The patients also showed significant higher frequency of allele “C” (25% vs 12% which was associated with increased breast cancer risk with an Odds ratio of 2.4444 (95% CI: 1.1967–4.9931. Testing the dominant model of inheritance revealed a statistically higher frequency of exposed genotypes “AC and CC” among the patients group (47.1% vs 24%, respectively; p = 0.013 with substantial increase in breast cancer risk among the exposed genotypes with an Odds ratio of 2.8243 (95% CI: 1.2679–6.2913. The present study demonstrated that (AC and CC genotypes of AT1R A1166C SNP and increased BMI can be considered as predictors for breast cancer risk among post menopausal Egyptian females. Results also revealed that A1166C SNP of AT1R gene and ACE/ID polymorphism could not be considered as predictors for breast cancer prognosis.

  2. Atividade física habitual e risco cardiovascular na pós-menopausa Habitual physical activity and cardiovascular risk in post menopause

    Directory of Open Access Journals (Sweden)

    Raimunda Beserra da Silva

    2006-08-01

    Full Text Available OBJETIVO: Avaliar a prevalência de atividade física habitual e risco cardiovascular em mulheres na pós-menopausa. MÉTODOS: Estudo de coorte transversal com 162 mulheres, entre 40 e 65 anos, em amenorréia há no mínimo 12 meses, acompanhadas no Ambulatório de Menopausa do CAISM/UNICAMP. As mulheres responderam oralmente o questionário International Physical Activity Questionnaire para avaliação do nível de atividade física, que abordou a freqüência e duração das atividades ocorridas durante uma semana normal, realizadas no transporte, trabalho, em casa e no lazer, classificando-as em sedentárias, insuficientemente ativas, ativas e muito ativas. Foram realizados exames laboratoriais para dosagem sérica de colesterol total, lipoproteína de alta densidade, lipoproteína de baixa densidade, triglicérides, glicemia de jejum e medidas de pressão arterial sistólica e diastólica. RESULTADOS: A média de idade das mulheres foi de 56,5 anos e idade na menopausa de 46 anos. A prevalência de atividade física foi de 83,3%, sendo que 2,5% foram classificadas como muito ativas, 80,8% ativas e 16,7% insuficientemente ativas. A maioria realizava atividades, principalmente no transporte e em casa, e apenas 38,3% realizavam atividade física durante o lazer. Nesta população, 87,7% das mulheres apresentavam escore de Framingham inferior a 10, considerado de baixo risco cardiovascular. CONCLUSÃO: Mulheres na pós-menopausa apresentam alta prevalência de atividade física habitual e baixa aderência ao exercício físico. O risco cardiovascular foi baixo na população estudada. É importante incentivar e orientar esta população a praticar atividade física compatível com suas condições físicas, estimulando a prática não somente da atividade física habitual, mas também do exercício físico.BACKGROUND: To evaluate the prevalence of habitual physical activity and cardiovascular risk in postmenopausal women. METHODS: A cross

  3. Reproductive factors and Parkinson's disease risk in Danish women

    DEFF Research Database (Denmark)

    Greene, N; Lassen, C F; Rugbjerg, K;

    2014-01-01

    BACKGROUND AND PURPOSE: Parkinson's disease is more common in men than women by a ratio of about 1.5:1 and yet there is no consensus to date as to whether female reproductive factors including hormone use affect Parkinson's disease risk. Our objective was to examine the relationship between...... and fertile life length, age at menopause or post-menopausal hormone treatment was found. CONCLUSIONS: Reproductive factors related to women's early- to mid-reproductive lives appear to be predictive of subsequent Parkinson's disease risk whereas factors occurring later in life seem less important....

  4. From pralines to multinationals. The economic history of Belgian chocolate

    OpenAIRE

    Garrone, Maria; Pieters, Hannah; Swinnen, Jo

    2015-01-01

    Belgium is associated with high-quality chocolate products and Belgian companies play an important role in cocoa processing. However, in historical perspective the global success and reputation of Belgian chocolate is a relatively recent phenomenon. Especially since the 1980s exports of "Belgian chocolates" have grown exponentially. We document the growth of the sector and discuss its determinants. Today, the very concept of "Belgian chocolate" faces challenges, as successful companies have b...

  5. Cross-sectional and longitudinal risk of physical impairment in a cohort of postmenopausal women who experience physical and verbal abuse

    OpenAIRE

    Cannell, M. Brad; Weitlauf, Julie C.; Garcia, Lorena; Andresen, Elena M; Margolis, Karen L.; Todd M. Manini

    2015-01-01

    Background Exposure to interpersonal violence, namely verbal and physical abuse, is a highly prevalent threat to women’s health and well-being. Among older, post-menopausal women, several researchers have characterized a possible bi-directional relationship of abuse exposure and diminished physical functioning. However, studies that prospectively examine the relationship between interpersonal abuse exposure and physical functioning across multiple years of observation are lacking. To address ...

  6. Performance of X-ray absorptiometry in post-menopausal vertebral osteoporosis. Discriminant value of vertebral and femoral measurements, fracture threshold, reproducibility

    International Nuclear Information System (INIS)

    The aim of this study was to assess the performance of a new bone densitometry technique, X-ray absorptiometry, in vertebral osteoporosis with fracture(s). Vertebral and femoral (neck, Ward's triangle and trochanter) bone density was measured in 60 women with at least one vertebral compression fracture of osteoporotic origin (mean age: 61), 100 controls of the same age and in 40 young adults (mean age: 30). Osteoporosis patients had significantly (p2, this value giving the best compromise between sensitivity (83%) and specificity (95%) with 91% of subjects appropriately classifed. Reproducibility was assessed in the short term in 9 osteoporosis patients. The mean standard deviation of measurements was 0.017 g/cm2 (coefficient of variation: 2.6%) as compared with 0.010 g/cm2 (coefficient of variation: 0.8%) in the young adult. These results emphasise the true advance represented by X-ray absorptiometry in the area of bone densitometry, notably in the assessment and monitoring of demineralisation disorders

  7. Prospects for Revitalising the Belgian University System.

    Science.gov (United States)

    Hecquet, Ignace

    1984-01-01

    Concerns of a researcher in a Belgian university regarding the trend toward policy implementation dominated by short- and medium-term budgetary considerations are outlined. The university system's heterogeneous, compartmentalized nature and potential are noted, along with the relationship to the government and the real danger of break-up of the…

  8. Performance communication of the Belgian Railway

    NARCIS (Netherlands)

    Gelders, Dave; Verckens, Jan Pieter; Galetzka, Mirjam; Seydel, Erwin

    2007-01-01

    Purpose – The purpose of this paper is to provide an insight into performance communication from an important public service, i.e. the Belgian Railway, towards its employees (internal) and stakeholders (external). Design/methodology/approach – A qualitative research approach was taken in the form o

  9. Risk factors for cardiovascular disease in women: relationship to lipid peroxidation and oxidative stress.

    Science.gov (United States)

    Castelao, J Esteban; Gago-Dominguez, Manuela

    2008-01-01

    Many risk factors that promote cardiovascular disease (CVD) have been identified. These include hypertension, hypercholesterolemia, diabetes, decreased estrogen in post-menopausal women, increased homocysteine, and cigarette smoking. It has recently become clear that a mechanism common to these risk factors is oxidative stress. CVD risk factors specific to women are parity, oophorectomy, pre-eclampsia, and menopause. There are several proposed mechanisms to explain these women-specific associations, such as reduced lifetime exposure to estrogen and insulin resistance, but the underlying mechanism is still unclear. One fact that did not receive much attention is the role of the oxidation hypothesis in these reproductive factors-CVD associations. In fact, pregnant, oophorectomized, and post-menopausal women exhibit higher levels of lipid peroxidation than non-pregnant, non-oophorectomized and pre-menopausal women, respectively. We propose that the increased levels of lipid peroxidation during these states are responsible, at least in part, for their increased risk of CVD. This review extends the concept of the oxidation hypothesis of CVD to reproductive risk factors in women. It also addresses the potential role of oxidative stress in the hyperthyroidism-CVD relationship, as hyperthyroidism is a common disorder that most frequently occurs in women. We also discuss how screening human populations for reactive oxygen species (ROS) levels could help identify groups with a high level of ROS that may be at risk of developing CVD. PMID:18308480

  10. The association between cardiorespiratory fitness and abdominal adiposity in postmenopausal, physically inactive South Asian women

    Directory of Open Access Journals (Sweden)

    I.A. Lesser

    2015-01-01

    Full Text Available In South Asians, a unique obesity phenotype of high abdominal fat is associated with increased cardiovascular risk. Low cardiorespiratory fitness (CRF is associated with abdominal fat and an increased risk of cardiovascular disease. The purpose of this paper is to determine whether CRF as assessed by VO2 peak, in post-menopausal South Asian women, was associated with body fat distribution and abdominal fat. Physically inactive post-menopausal South Asian women (n = 55 from the Greater Vancouver area were recruited and assessed from January to August 2014. At baseline, VO2 peak was measured with the Bruce Protocol, abdominal fat with CT imaging, and body composition with dual energy X-ray absorptiometry. ANOVA was used to assess differences in subcutaneous abdominal adipose tissue (SAAT, visceral adipose tissue (VAT and total abdominal adipose tissue (TAAT between tertiles of CRF. Bivariate correlation and multiple linear regression analyses explored the association between VO2 peak with SAAT, VAT, TAAT and body composition. Models were further adjusted for body fat and body mass index (BMI. Compared to women in the lowest tertile of VO2 peak (13.8–21.8 mL/kg/min, women in the highest tertile (25.0–27.7 mL/kg/min had significantly lower waist circumference, BMI, total body fat, body fat percentage, lean mass, SAAT, VAT and TAAT (p < 0.05. We found VO2 peak to be negatively associated with SAAT, VAT and TAAT, independent of age and body fatness but not independent of BMI. Further research is necessary to assess whether exercise and therefore improvements in CRF would alter SAAT, VAT and TAAT in post-menopausal South Asian women.

  11. Intensity of climacteric symptoms in postmenopausal women

    Directory of Open Access Journals (Sweden)

    Thaiene Rodrigues dos Santos

    2016-05-01

    Full Text Available Objective: to evaluate the characteristics and intensity of climacteric symptoms in postmenopausal women. Methods: a cross-sectional, descriptive study with systematic probabilistic sampling, consisting of 247 women in post menopause, who answered the Questionnaire of Women’s Health. To evaluate the intensity of climacteric symptoms the Menopausal Index of Blatt and Kupperman was used. Statistical analysis was performed using the Statistical Package for Social Sciences software version 17, a significance level of 5% and 95% confidence intervals for all analyzes were adopted. Results: 36.8% of women had mild climacteric symptoms, 56.3% moderate and 6.9% severe. In descending order hot flushes, irritability and sleep disorders reached the highest intensity ratios. Conclusion: the Menopausal index of Blatt and Kupperman (25.34 showed symptoms of moderate intensity. Hot flushes showed to be the symptom of highest intensity of discomfort.

  12. Focal epilepsy in the Belgian shepherd

    DEFF Research Database (Denmark)

    Berendt, Mette; Gulløv, Christina Hedal; Fredholm, Merete

    2009-01-01

    OBJECTIVES: To establish the mode of inheritance and describe the clinical features of epilepsy in the Belgian shepherd, taking the outset in an extended Danish dog family (199 individuals) of Groenendael and Tervueren with accumulated epilepsy. METHODS: Epilepsy positive individuals (living and...... deceased) were ascertained through a telephone interview using a standardised questionnaire regarding seizure history and phenomenology. Living dogs were invited to a detailed clinical evaluation. Litters more than five years of age, or where epilepsy was present in all offspring before the age of five...... seizures. In seven dogs, seizures could not be classified. The mode of inheritance of epilepsy was simple Mendelian. CLINICAL SIGNIFICANCE: This study identified that the Belgian shepherd suffers from genetically transmitted focal epilepsy. The seizure phenomenology expressed by family members have a...

  13. Optical remote sensing of Belgian coastal waters

    OpenAIRE

    Ovidio, F.; K. Ruddick; Vasilkov, A.; Burenkov, V.

    2001-01-01

    This paper summarises the research conducted at MUMM in optical remote sensing of Belgian coastal waters during the period 1997-2000. The motivation for this research consists of the need to provide information for marine environmental management of coastal eutrophication and sediment transport related problems. The basic products provided by optical remote sensing are maps of chlorophyll concentration and total suspended matter. A key contribution has been made for the atmospheric correction...

  14. Advertising budgeting practices of Belgian industrial marketers.

    OpenAIRE

    François, Pierre

    2003-01-01

    The author reports on the results of a survey of a random sample of 102 belgian industrial companies, which measured which budget setting processes companies use, how they set budgets and the resulting budget composition. The objective of the study was first to compare the results with international practice, and second to try to explain their budgeting practices as a function of company, product and market characteristics measured in the same survey. The major conclusions are mixed : on the ...

  15. The Belgian Nuclear Higher Education Network

    International Nuclear Information System (INIS)

    Full text: BNEN, the Belgian Nuclear Higher Education Network has been created in 2001 by five Belgian universities and the Belgian Nuclear Research Centre (SCK-CEN) as a joint effort to maintain and further develop a high quality programme in nuclear engineering in Belgium. In a country where a substantial part of electricity generation will remain of nuclear origin for a number of years, there is a need for well educated and well trained engineers in this area. Public authorities, regulators and industry brought their support to this initiative. In the framework of the new architecture of higher education in Europe, the English name for this 60 ECTS programme is 'Master of Science in Nuclear Engineering'. To be admitted to this programme, students must already hold a university degree in engineering or equivalent. Linked with university research, benefiting from the human resources and infrastructure of SCK-CEN, encouraged and supported by the partners of the nuclear sector, this programme should be offered not only to Belgian students, but also more widely throughout Europe and the world. The master programme is a demanding programme where students with different high level backgrounds in engineering have to go through highly theoretical subjects like neutron physics, fluid flow and heat transfer modelling, and apply them to reactor design, nuclear safety and plant operation and control. At a more interdisciplinary level, the programme includes some important chapters of material science, with a particular interest for the fuel cycle. Radiation protection belongs also to the backbone of the programme. All the subjects are taught by academics appointed by the partner universities, whereas the practical exercises and laboratory sessions are supervised by researchers of SCK-CEN. The final thesis offers an opportunity for internship in industry or in a research laboratory. More information: http://www.sckcen.be/BNEN. (author)

  16. Avaliação tecnológica em saúde: densitometria óssea e terapêuticas alternativas na osteoporose pós-menopausa Technology assessment in health care: bone densitometry and alternatives therapeutical in post-menopausal osteoporosis

    Directory of Open Access Journals (Sweden)

    Leticia Krauss Silva

    2003-08-01

    Full Text Available Este artigo apresenta de forma sucinta os fatores considerados e as metodologias de síntese empregadas em uma avaliação tecnológica, assim como a lógica subjacente à sua elaboração e utilização no campo da saúde pública. O exemplo utilizado focaliza o problema osteoporose na pós-menopausa, analisando a oportunidade da difusão, no momento atual, da densitometria óssea e de tecnologias antiosteoporose em nosso país. Os estudos disponíveis sobre os efeitos das tecnologias envolvidas foram revisados, seguindo a metodologia recomendada, a fim de produzir uma síntese das evidências científicas, atualizada e aplicada ao nosso país. Análises de custo-efetividade preliminares de alternativas de intervenção, frente à assistência tradicional, são apresentadas, considerando mulheres na perimenopausa e com 65 anos de idade. A despeito das hipóteses otimistas assumidas, as estimativas de custo incremental por fratura evitada foram elevadas, todas acima de R$ 10.000,00 para quaisquer das alternativas de intervenção examinadas, sendo o custo médio estimado das fraturas assistidas dentro da alternativa tradicional inferior a R$ 2.000,00, o que indica que a implementação no SUS de qualquer uma das alternativas em pauta seria questionável segundo critérios de eficiência no uso de recursos e de eqüidade.This article briefly presents the target factors and methods for summarizing evidence employed in a technological evaluation, as well as the underlying logic in their elaboration and utilization in the field of public health. The example is post-menopausal osteoporosis, analyzing the current timeliness of disseminating bone densitometry and technologies to combat osteoporosis in Brazil Available studies on the effects of the respective technologies were reviewed according to the recommended methodology in order to produce a synthesis of the scientific evidence, updated and applied in Brazil. Preliminary cost-effective analyses of

  17. Religiosity, Values, and Acculturation: A Study of Turkish, Turkish-Belgian, and Belgian Adolescents

    Science.gov (United States)

    Gungor, Derya; Bornstein, Marc H.; Phalet, Karen

    2012-01-01

    We address the understudied religious dimension of acculturation in acculturating adolescents who combine a religious Islamic heritage with a secularized Christian mainstream culture. The religiosity of 197 Turkish-Belgian adolescents was compared with that of 366 age-mates in Turkey (the heritage culture) and 203 in Belgium (the mainstream…

  18. NON-INVASIVE RISK FACTORS OF NON-COMMUNICABLE DISEASES IN PRE AND POSTMENOPAUSAL WOMEN OF VADODARA: A PILOT STUDY

    Directory of Open Access Journals (Sweden)

    Pooja Gaur

    2013-08-01

    Full Text Available Non-communicable diseases have emerged as a predominant cause of deaths for women worldwide. Earlier post-menopausal women were thought to be at higher risk for chronic degenerative diseases, as protective effect of oestrogen is lost after menopause. Whereas in the last decade, alarming trends for these diseases are seen among women in their child bearing age. Hence the aim of the study was to assess non-invasive risk factors of noncommunicable diseases among adult females with a focus on menopause. For this purpose, 408 females were screened and after excluding cases of peri-menopause, under-nutrition, pregnancy and hysterectomy, based on consent detailed non-invasive risk analysis was performed on 131 female subjects. The results revealed that the prevalence of selfreported history of hypertension and diabetes was around 21% and 11% respectively. About 75% of the subjects were overweight or obese according to Asia Pacific Classification. Post-menopausal women had significantly high prevalence of high body fat per cent (OR 6.52, 95%CI 1.32-62.3 and high blood pressure (OR 4.4 95%CI 2.1-9.3. Mean waist circumference, waist hip ratio, waist stature ratio, body fat and systolic blood pressure were above the normal cut-offs depicting presence of risks in both the groups. A trend of high per capita consumption of oil, salt and sugar at household level was seen. The frequency of practice of regular health check-up and awareness regarding selfbreast examination was very low among the subjects. The study indicates high prevalence of non-communicable disease risks among both pre and post-menopausal women, emphasizing the need to create awareness among young female population to adapt healthy lifestyle practices.

  19. Distribution of doses resulting from cosmic rays exposure for Belgian airlines

    International Nuclear Information System (INIS)

    The Belgian Radiation Protection Act of 2001 requires air line companies registered in Belgium to evaluate the doses resulting from the exposure of their crew to cosmic radiation. If the annual dose of 1 mSv is exceeded, the crew must be informed about their individual doses and pregnant women have to be protected, among other measures. The Federal Agency for Nuclear Control (FANC, the competent Belgian radiation protection authority) has issued guidelines in order to help air line companies to fulfil their duties. Following the publication of these guidelines, all commercial Belgian air line companies have sent data on the exposure of their personnel. These data and, in particular, the distribution of the doses are presented. Except in the cases of small 'air taxi' companies, which fly only on very short distances and low altitudes, a significant number of air crew members gets doses of more than 1 mSv/y. The maximum value amounts to ∼ 4 mSv/y. The computer codes used by the companies in order to evaluate the individual doses are PCAIRE, CARI and IASON-FREE. The FANC imposed the concerned companies to reassess yearly the individual doses. (author)

  20. Belgian Photography: Towards a Minor Photography.

    OpenAIRE

    Jan Baetens; Hilde Van Gelder; Mieke Bleyen

    2011-01-01

    Abstract: This article investigates Belgian photography from within the national framework. Using the notion of "banal nationalism" (Billig), it explores how even in the case of a nation wi...

  1. Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women

    OpenAIRE

    Timothy R Rebbeck; DeMichele, Angela; Tran, Teo V.; Panossian, Saarene; Bunin, Greta R.; Troxel, Andrea B.; Strom, Brian L

    2008-01-01

    FGFR2 and MAP3K1 are members of the RAS/RAF/MEK/ERK-signaling pathway and have been identified from genome-wide association studies to be breast cancer susceptibility genes. Potential interactions of these genes and their role with respect to tumor markers, hormonal factors and race on breast cancer risk have not been explored. We examined FGFR2 and MAP3K1 variants, breast tumor characteristics and hormone exposures in a population-based case–control sample of 1225 European-American (EA) and ...

  2. Belgian NPPS fit passive autocatalytic recombiners

    International Nuclear Information System (INIS)

    Because hydrogen production during severe accidents can endanger the containment or safety-graded equipment, the Belgian Utility requested Belgatom in 1989 to perform a comparative study between the possible mitigative measures. From the outcome of that study, the Utility decided to install Passive Autorcatalytic Recombiners (PARs) in the seven Belgian units and mandated Belgatom to carry out the project. The author presents the successive steps from the principle decision to the installation on site. A first section is devoted to the sizing of the catalytic surface and its distribution inside the containment. The results of the method are presented for the 5 units equipped before October 96. Besides the functional requirements, the catalyst must also resist to poisoning agents which can be released not only during severe accidents but also during normal operation or shutdown; the relevant qualification criteria are reminded in the second section. Because the installation of the PARs requires also the design of supports, recommendations are drawn to minimize the design effort and the assembling work. At last, the effectiveness of the PARs entirely relies on a catalyst material of which the potential has to be periodically controlled. A section briefly describes the in-service inspection and the related test procedures

  3. BRAMS --- the Belgian RAdio Meteor Stations

    Science.gov (United States)

    Lamy, H.; Ranvier, S.; Martinez Picar, A.; Gamby, E.; Calders, S.; Anciaux, M.; De Keyser, J.

    2014-07-01

    BRAMS is a new radio observing facility developed by the Belgian Institute for Space Aeronomy (BISA) to detect and characterize meteors using forward scattering. It consists of a dedicated beacon located in the south-east of Belgium and in 25 identical receiving stations spread over the Belgian territory. The beacon transmits a pure sinusoidal wave at a frequency of 49.97 MHz with a power of 150 watts. A complete description of the BRAMS network and the data produced will be provided. The main scientific goals of the project are to compute fluxes, retrieve trajectories of individual objects, and determine physical parameters (speed, ionization, mass) for some of the observed meteor echoes. All these goals require a good knowledge of the radiation patterns of the transmitting and receiving antennas. Simulations have been made and will be validated with in-situ measurements using a UAV/drone equipped with a transmitter flying in the far-field region. The results will be provided. Each receiving station generates around 1 GB of data per day with typical numbers of sporadic meteor echoes of 1500--2000. An automatic detection method of these meteor echoes is therefore mandatory but is complicated by spurious echoes mostly due to airplanes. The latest developments of this automatic detection method will be presented and compared to manual counts for validation. Strong and weak points of the method will be presented as well as a possible alternative method using neural networks.

  4. Contact allergy caused by methylisothiazolinone: the Belgian-French experience.

    Science.gov (United States)

    Aerts, Olivier; Goossens, An; Giordano-Labadie, Françoise

    2015-01-01

    The chemical Kathon CG(®), a mixture of the preservatives methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI), was the leading cause of a worldwide epidemic of contact-allergic reactions in the eighties. From 2000 on, MI alone became allowed in industrial products and in 2005 authorities gave a green light for its use in leave-on and rinse-off cosmetics up to a maximum concentration of 100 ppm (0.01%). Following initial occupational cases, a continuously increasing number of consumers sensitized to MI have been reported and both Belgian and French allergy groups decided to routinely test MI in their baseline series from 2010 onwards. Two multicenter studies, comprising 8,680 and 7,874 patients in Belgium and France respectively, both clearly show the rise in contact allergy caused by MI, with a spectacular sensitization rate of ∼ 6.0% in 2012, even increasing to 7.0% in 2013. Mostly middle-aged women, presenting with facial-and/or hand dermatitis, were affected, although very young children were reported as well. Furthermore, the data confirmed that sensitization is primarily caused by cosmetics (mostly leave-on, but also rinse-off), household detergents and water-based paint. This unprecedented outbreak of contact sensitization to a preservative agent in Europe, and beyond, should have alerted the authorities much sooner and meanwhile the need for safer use concentrations of MI in cosmetics, detergents and industrial products is becoming more urgent every day. PMID:26412037

  5. Effect of calcium and soy isoflavone supplementation on bone mineral density of women with different menstrual status

    Institute of Scientific and Technical Information of China (English)

    Asma Rashid; Rukhshan Khurshid; Asif Hanif; Mahjabeen Saleem; Latif Aftab

    2012-01-01

    In order to find out the effective alternative treatments in peri- and post-menopausal women,we carried out the research.Study design was observational experimental study with duration of 6 mon.A total of 250 female subjects were included in the study.Results showed that the bone mass density or T-score in menstruating women was increased after the use of calcium and showed a highly significant difference (P<0.001).In both peri- and post-menopausal women,the values of bone mass density or T-score was non significantly increased after the use of calcium.Values of bone mass density in peri- and postmenopausal women were significantly increased (P<0.001) after the use of phytoestrogen.It is concluded that phytoestrogen is a better treatment therapy of osteopenia/osteoporosis as compared to calcium treatment.However further research is needed in large number of women to meet a better conclusion.

  6. History of the Belgian nuclear power controversy

    International Nuclear Information System (INIS)

    Partly because nuclear energy technology continues to provoke profound controversy, the Flemish institute for technology assessment (viWTA) took the initiative to order a study aimed at mapping out the historical dynamics of the societal debate on nuclear energy. This study was carried out by the Belgian Nuclear Research Centre (SCK-CEN, under the research programme PISA) together with the Free university of Brussels (VUB, research group MEKO) in 2004. In 2007, the report was updated and published by Acco (Leuven) under the title Kernenergie (on)besproken. This study had three main objectives: 1) to discuss the societal debate on nuclear energy in Belgium in relation to major events (Chernobyl, TMI, etc.); 2) to elucidate the role of social actors in the controversy on both a national and international level and 3) to discuss possible alternatives for a better structuring of the debate in the future, building on existing approaches

  7. Immune activation in HIV-infected aging women on antiretrovirals--implications for age-associated comorbidities: a cross-sectional pilot study.

    Directory of Open Access Journals (Sweden)

    Maria L Alcaide

    Full Text Available Persistent immune activation and microbial translocation associated with HIV infection likely place HIV-infected aging women at high risk of developing chronic age-related diseases. We investigated immune activation and microbial translocation in HIV-infected aging women in the post-menopausal ages.Twenty-seven post-menopausal women with HIV infection receiving antiretroviral treatment with documented viral suppression and 15 HIV-negative age-matched controls were enrolled. Levels of immune activation markers (T cell immune phenotype, sCD25, sCD14, sCD163, microbial translocation (LPS and biomarkers of cardiovascular disease and impaired cognitive function (sVCAM-1, sICAM-1 and CXCL10 were evaluated.T cell activation and exhaustion, monocyte/macrophage activation, and microbial translocation were significantly higher in HIV-infected women when compared to uninfected controls. Microbial translocation correlated with T cell and monocyte/macrophage activation. Biomarkers of cardiovascular disease and impaired cognition were elevated in women with HIV infection and correlated with immune activation.HIV-infected antiretroviral-treated aging women who achieved viral suppression are in a generalized status of immune activation and therefore are at an increased risk of age-associated end-organ diseases compared to uninfected age-matched controls.

  8. Exporting Ethnic Divisions? The Political Participation of Belgian Citizens Abroad

    OpenAIRE

    Lafleur, Jean-Michel

    2011-01-01

    The Belgian emigrants’ political participation in home country politics is an issue that has undergone several important developments since the end of the 1990s but has surprisingly been subject to very little research. The absence of the issue of emigration from the Belgian political agenda combined with the limited engagement of this population with the home country thus stands for the absence of research on the topic. The lack of academic interest, in turn, has favoured the development of ...

  9. Dietary habits during adolescence - results of the Belgian Adolux Study

    OpenAIRE

    Paulus, Dominique; Saint-Remy, Annie; JeanJean, Michel

    2001-01-01

    STUDY: To analyse the usual dietary habits of Belgian adolescents from a high cardiovascular risk population. METHODS: A food frequency questionnaire (57 items) was administered to the whole sample. Complementary questions specified some types of food (eg fat content). A subgroup of 234 adolescents gave detailed information on portion size (picture book and food samples). SETTING: Twenty-four secondary schools in the Belgian province of Luxembourg. SUBJECTS: A total of 1,526 adolesce...

  10. Survival Among Belgian Centenarians (1870-1894 Cohorts)

    OpenAIRE

    Liu Yuzhi; Zhang Chunyuan; Foulon, M.; D. Chambre; Poulain, M.

    2001-01-01

    Poulain Michel, Chambre Dany, Foulon Michel.- Survival Among Belgian Centenarians (1870-1894 Cohorts) Calculating the probability of dying among post-centenarians is problematic and often flawed by a high risk of error. This is partly due to the unreliability of statistical data on centenarians, and partly to the small populations concerned. The Belgian centenarian database of over 4,000 centenarians in the 1870 to 1894 birth cohorts used here endeavours to compensate for these two failings. ...

  11. Psychosocial predictors of actual turnover among Belgian health care workers

    OpenAIRE

    Derycke, Hanne; Vlerick, Peter; Clays, Els; D'hoore, William; Braeckman, Lutgart

    2010-01-01

    Background: Turnover of nursing staff is a major challenge for healthcare settings and for healthcare in general, urging the need to improve retention. Aim: The aim was to explore the prospective relations between personal and psychosocial work-related factors and actual turnover among Belgian healthcare workers. Methods: Predictors of actual turnover were assessed using the longitudinal Belgian data from the Nurses Early Exit Study (NEXT). Two self-administered questionnaires with a time...

  12. Fuel cycle transition - A Belgian implementation scenario

    International Nuclear Information System (INIS)

    At the end of 2002 the total installed electric power in Belgium was 16,200 MWe of which 40% (6485 MWe) corresponds to the seven nuclear power plants installed on the two Belgian sites of Doel (4 power plants) and Tihange (3 power plants) and the 25% participation in the two French Units B1 and B2 at Chooz at the Belgian-French border. The nuclear installed power in Belgium is 5800 MWe. In 2003, the government decided to phase out the nuclear energy progressively by closing the Belgian NPPs after 40 years of operation. This means that the first generation units (Doel 1, Doel 2 and Tihange 1) will be closed in 2015 and the four other remaining units in 2022-2025. Nevertheless, this phase out is subject to various conditions: the guarantee of energy independence should not be affected and the engagement to respect the Kyoto agreement (reducing the CO2 production by 7.5% in 2010 as compared to the 1990 production). Thus the phase-out decision can be re-opened if the above mentioned conditions are not met. The paper has the following contents: 1. Introduction; 2. Actual fuel cycle; 3. Transition fuel cycle; 4. Calculations; 4.1. PWR modelling; 4.2. ADS modelling; 4.3. Calculation code; 5. Results; 5.1. PWR/EPR; 5.2. ADS; 6. Conclusions. In conclusion it is shown that the evaluated stock pile of waste in Belgium (with no increase of electricity demand) coming from the thermal reactors park is 4380 tons (52 t Pu, 9 t MA, 217 t FP) with phase out (i.e. between 1975, first PWR and 2025, last PWR) and 7825 tons (84 t Pu, 20 t MA, 381 t FP) without phase out (i.e. between 1975, first PWR and 2075, last EPR). According to this study, Belgium should keep all its first generation Pu for the eventual starting of the self burning FR. Indeed, the Pu needed to start the self burning FR is evaluated between 60 t and 90 t (based on 10 t to 15 t per GWe). With an homogeneous core loading, 54% of the MA could be eliminated after 24 years in three 600 MWth industrial ADS (corresponding

  13. Mechanical degradation processes: The Belgian experience

    International Nuclear Information System (INIS)

    Design life is merely used in Belgium as a requirement in the 'Design Specification' of some components subjected to known degradation processes, such as stress induced fatigue, embrittlement (irradiation or other), various types of corrosion, wear, erosion, thermal aging (electrical insulation, ...), etc. Design life is in no way directly related to the duration of the plant operation. In that sense design life for the Belgian NPP components includes the values of 20, 30 and 40 years. The oldest plant (20 years design life) has been decommissioned in 1991. The most recent units (40 years design life) have still a good time to go. The intermediate units (30 years design life) started around 1975. Consequently components of these plants need be looked at to determine whether or not deteriorations have occurred. The paper presents the various known mechanical degradation processes and how they affect various components. Emphasis is laid on prevention, mitigation or repair measures that have been or are being taken to avoid that the 'Equipment design life' be the limiting factor in the duration of the plant operation. (author)

  14. Different compositions of pharmaceuticals in Dutch and Belgian rivers explained by consumption patterns and treatment efficiency

    NARCIS (Netherlands)

    Laak, ter T.L.; Kooij, P.J.F.; Tolkamp, H.; Hofman, J.

    2014-01-01

    In the current study, 43 pharmaceuticals and 18 transformation products were studied in the river Meuse at the Belgian-Dutch border and four tributaries of the river Meuse in the southern part of the Netherlands. The tributaries originate from Belgian, Dutch and mixed Dutch and Belgian catchments. I

  15. The Resilience Scale for Adults: Construct Validity and Measurement in a Belgian Sample

    Science.gov (United States)

    Hjemdal, Odin; Friborg, Oddgeir; Braun, Stephanie; Kempenaers, Chantal; Linkowski, Paul; Fossion, Pierre

    2011-01-01

    The Resilience Scale for Adults (RSA) was developed and has been extensively validated in Norwegian samples. The purpose of this study was to explore the construct validity of the Resilience Scale for Adults in a French-speaking Belgian sample and test measurement invariance between the Belgian and a Norwegian sample. A Belgian student sample (N =…

  16. Inventory of nuclear liabilities - The Belgian perspective

    International Nuclear Information System (INIS)

    Like all countries that use radioactive materials for producing electricity or for other peaceful purposes, Belgium is faced with an important challenge: the safe management of all these materials, in both the short and long term. Of course there is a price to pay for this management, which in accordance with the ethical principle of inter-generational fairness should be borne mainly by the current generations. However, it is possible that when the moment has come, the financial resources to cover the costs of decommissioning and remediation of these installations, prove to be insufficient or even completely non-existent: this then results in a nuclear liability. This kind of situation can have several causes, such as an underestimation of the actual costs by the operator or the owner of the nuclear installation or by the holder or the owner of the radioactive materials, negligence, transfer of ownership of the nuclear installation or the nuclear site without transfer of the corresponding provisions, a reduction in the operating time, a bankruptcy as well as ignorance. Because it wishes to avoid the occurrence of new nuclear liabilities, the Belgian legislator, by virtue of article 9 of the programme law of 12.12.97, charged ONDRAF/NIRAS, the Belgian Agency for Radioactive Waste and Enriched Fissile Materials, with collecting all the elements that are necessary in order to examine to which degree the decommissioning and remediation costs can be actually covered when the time comes. ONDRAF/NIRAS was specifically charged with ascertaining all facts of a technical and financial nature which should enable the minister responsible for energy to verify whether every operator or owner of a nuclear installation and every holder or owner of radioactive materials have provided in time for the requisite financial resources to cover the future costs of decommissioning and remediation. This evaluation of course also serves to enable the government to take the necessary

  17. A CO2-strategy for BTC [Belgian Development Agency

    Energy Technology Data Exchange (ETDEWEB)

    Bailly, J. [Prospect C and S, Brussels (Belgium); Hanekamp, E. [Partners for Innovation, Amsterdam (Netherlands)

    2008-09-15

    The CO2 footprint is determined the CO2 strategy is developed for the Belgian Technical Cooperation (BTC). BTC is the Belgian agency for development cooperation, and finances development projects in 23 partner countries. The CO2 footprint covered BTC's activities in 2007 in all their offices worldwide. Footprint and strategy were finalised and adopted by the Executive Board at the end of 2008. Meanwhile, the BTC began with the introduction of the proposed strategy. Partners for Innovation and Prospect were asked to support the introduction of the strategy and to determine the CO2 footprint of 2008.

  18. Coastal flooding risk calculations for the Belgian coast

    OpenAIRE

    Verwaest, T.; Van der Biest, K.; Vanpoucke, Ph.; Reyns, J.; Vanderkimpen, P.; de Vos, L.; De Rouck, J.; Mertens, T.

    2009-01-01

    Coastal flooding risk calculations are carried out for the entire Belgian coastal zone to support the management ofthe coastal defence system. The floodprone low-lying coastal area has an average width of 20 km and is locatedon average 2 m below the surge level of an annual storm. The natural sea defences are sandy beaches anddunes, which have been strengthened by revetments in the coastal towns. The Belgian standard of coastalprotection is to be safe against a surge level with a return perio...

  19. Reversible increase of serum activin A levels in women with Graves' disease.

    Science.gov (United States)

    Centanni, M; Viceconti, N; Luisi, S; Reis, F M; Gargano, L; Maiani, F; Franchi, A; Canettieri, G; Petraglia, F

    2002-12-01

    The aim of this study was to analyze the serum levels of activin A in hyperthyroid patients with Graves' disease. Serum activin A and FSH levels were measured in a total of 93 females (64 regularly cycling and 29 post-menopausal). Of these, 20 were hyperthyroid patients with Graves disease, 33 were euthyroid goitrous patients (20 had autoimmune thyroiditis AT and 13 only had goiter) representing the internal control group and 40 were healthy subjects representing the external control group. Serum levels of activin A were higher in goitrous patients with AT than in control subjects (p=0.0388). Activin A levels were almost doubled in the cycling and in post-menopausal hyperthyroid women (0.91+/-0.21 vs 0.43+/-0.07 microg/l; phyperthyroid patients, studied even after methimazole treatment, that increase was substantially reversed, once euthyroidism was attained (p=0.002). These findings indicate that thyroid function and autoimmune processes significantly affect serum levels of activin A in patients with Graves' disease. PMID:12553556

  20. Validation of the IMMIDIET food frequency questionnaire in an adult Belgian population: a report from the Belgian case-control study on bladder cancer risk.

    Science.gov (United States)

    Brinkman, M T; Kellen, E; Zeegers, M P; van Dongen, M C J M S; Dagnelie, P C; Muls, E; Buntinx, F

    2011-01-01

    We evaluated the performance of the IMMIDIET food frequency questionnaire (FFQ) used to collect dietary data for the Belgian case-control study on bladder cancer. Thirty-seven men and women aged 50 years and older were recruited from the University Hospital in Leuven, Belgium. Participants completed the IMMIDIET FFQ, a 7-day diet diary and a 24-hour diet recall. Median intakes and inter-quartile ranges were calculated for 27 foods and nutrients from each dietary assessment method. All dietary factors were log-transformed and adjusted for energy using the nutrient density method. Pearson correlation coefficients were used to compare the different dietary assessment methods. Bland-Altman plots were also used to assess levels of agreement between the dietary methods. Energy, fruit and vegetable intake estimates were higher from the IMMIDIET FFQ compared with the two reference methods.The highest deattenuated correlations between the FFQ and 7-day diary were meat (0.58), bread (0.44), fruit (0.38) and fish (0.38). The highest deattenuated correlations between the FFQ and 24-hour recall were for fruit (0.72), fat (0.48), alcohol (0.44), cholesterol (0.42), monounsaturated fatty acid (0.42) and polyunsaturated fatty acid (0.41). Generally, correlation was lower for the micro-nutrients except for phosphorus (0.42), vitamin C (0.41) and calcium (0.40). The IMMIDIET FFQ is an appropriate instrument to measure usual dietary intake for the Belgian case-control study on bladder cancer risk. Further investigation of nutritional assessment methods is necessary. PMID:21485759

  1. EC initiatives promise mixed blessings: a Belgian utility perspective

    International Nuclear Information System (INIS)

    The potential effects on nuclear power of European Community initiatives are analysed from the viewpoint of a Belgian utility. The initiatives fall under the three broad headings of: East-West co-operation; completing the internal market; and carbon dioxide emission. (Author)

  2. Belgian support programme to the IAEA for safeguards implementation

    International Nuclear Information System (INIS)

    The objective of the Belgian Support Programme (BEL SP) is to contribute to the optimization of safeguards measures in accordance with INFCIRC/153 type agreements. This optimization has to take into account cost and effectiveness for the Agency, for the State System of Accounting and Control, for the plant operator and for EURATOM, which is considered an inherent partner. The Belgian support programme has undertaken a series of tasks covering the following domains: Non-destructive Measurement Technology (high resolution gamma spectroscopy, neutron measurements on powders, pins, assemblies and waste, test of Phonid, calorimetry on Pu samples, input tank calibration in a reprocessing plant, combined neutron and gamma measurements on irradiated fuel assemblies, allowing the estimation of burnup, plutonium content and cooling time, measurements of coincidence neutrons from fresh MOX fuel assemblies stored under water), System Studies, Analytical Measurements, Containment and surveillance, Training. Numerous field tests in Belgian in Belgian installations have led to a valuable contribution to the Support Programme to the IAEA, either on an individual basis or through a collaboration effort. In the past, the choice of tasks was based mainly on the availability of nuclear facilities; currently, the trend has shifted to technical contributions, system studies, possibly in a joint effort with other programmes. This approach follows the trend of on-going internationalisation of R and D

  3. The Dutch-Belgian beamline at the ESRF.

    Science.gov (United States)

    Borsboom, M; Bras, W; Cerjak, I; Detollenaere, D; Glastra Van Loon, D; Goedtkindt, P; Konijnenburg, M; Lassing, P; Levine, Y K; Munneke, B; Oversluizen, M; Van Tol, R; Vlieg, E

    1998-05-01

    A brief description is given of the design principles and layout of the Dutch-Belgian beamline at the ESRF. This beamline optimizes the use of the available bending-magnet radiation fan by splitting the beam into two branches, each accommodating two experimental techniques. PMID:15263564

  4. Continuing Vocational Training in Belgian Companies: An Upward Tendency

    Science.gov (United States)

    Buyens, Dirk; Wouters, Karen

    2005-01-01

    Purpose: As part of the European continuing vocational training survey, this paper aims to give an overview of the evolutions in continuing vocational training (CVT) in Belgian companies, by comparing both the results of the survey of 1994 and those of 2000/2001. Design/methodology/approach: In Belgium 1,129 companies took part in the survey of…

  5. The attitudes of Belgian adolescents towards peers with disabilities

    NARCIS (Netherlands)

    Bossaert, Goele; Colpin, Hilde; Pijl, Sip Jan; Petry, Katja

    2011-01-01

    This study aimed to explore Belgian adolescents' attitudes towards peers with disabilities and to explore factors associated with these attitudes. Based on the theory of persuasive communication, this study focused on receiver variables (the "whom"), characteristics of students with disabilities ("c

  6. Tai Chi for osteopenic women: design and rationale of a pragmatic randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Fischer Mary

    2010-03-01

    Full Text Available Abstract Background Post-menopausal osteopenic women are at increased risk for skeletal fractures. Current osteopenia treatment guidelines include exercise, however, optimal exercise regimens for attenuating bone mineral density (BMD loss, or for addressing other fracture-related risk factors (e.g. poor balance, decreased muscle strength are not well-defined. Tai Chi is an increasingly popular weight bearing mind-body exercise that has been reported to positively impact BMD dynamics and improve postural control, however, current evidence is inconclusive. This study will determine the effectiveness of Tai Chi in reducing rates of bone turnover in post-menopausal osteopenic women, compared with standard care, and will preliminarily explore biomechanical processes that might inform how Tai Chi impacts BMD and associated fracture risks. Methods/Design A total of 86 post-menopausal women, aged 45-70y, T-score of the hip and/or spine -1.0 and -2.5, have been recruited from primary care clinics of a large healthcare system based in Boston. They have been randomized to a group-based 9-month Tai Chi program plus standard care or to standard care only. A unique aspect of this trial is its pragmatic design, which allows participants randomized to Tai Chi to choose from a pre-screened list of community-based Tai Chi programs. Interviewers masked to participants' treatment group assess outcomes at baseline and 3 and 9 months after randomization. Primary outcomes are serum markers of bone resorption (C-terminal cross linking telopeptide of type I collagen, bone formation (osteocalcin, and BMD of the lumbar spine and proximal femur (dual-energy X-ray absorptiometry. Secondary outcomes include health-related quality-of-life, exercise behavior, and psychological well-being. In addition, kinetic and kinematic characterization of gait, standing, and rising from a chair are assessed in subset of participants (n = 16 to explore the feasibility of modeling skeletal

  7. Endocrine identification of menopausal status of Sudanese women

    International Nuclear Information System (INIS)

    the early peri-menopause with mild signs and symptoms to the late peri-menopausal stage which almost resembles the post-menopause. The new classification system using its three key tools had successfully classified the heterogeneous peri-menopausal stage into three distinct sub-classes with characteristic hormonal and symptomatic manifestation for each. The three subclasses are early peri-menopausal women who are characterized by presence of normal hormonal levels (FSH and LH) but who suffer amenorrhea. FSH level of this subclass although within the normal range, it is higher than that of the preceding class pre-menopausal stage, but the difference is not statistically significant. Therefore, women who suffer irregular cycles and amenorrhea due to other endocrine causes (hyperprolactinaemia, hypo- and hyperthyroidism, etc) can be mis classified as early peri-menopausal. Therefore, the other endocrine causes should be ruled out before including them in this subclass by measurement of respective hormones, namely, prolactin and TSH levels. The second subclass is the med peri-menopausal women who are characterized by elevated FSH levels but unlike the preceding subclass they do not suffer amenorrhea, the reason for this is not clear, but it seems the ovary is still secreting sufficient oestrogen levels to prime the uterus and maintains regular menstrual cycles. However, further research with a larger sample size is needed to clarify this situation. The third subclass is the late peri-menopausal women who are having elevated FSH levels, but normal LH levels and they suffer amenorrhea, indicating the beginning of cessation menstruation. The new classification scheme indicated that LH levels increase sharply immediately after menopause signaling the end of reproductive life and beginning of the post menopausal life. The new classification scheme indicated that early post-menopausal women are those who have elevated FSH and LH, but who experience a menstrual cycle during the

  8. Exploring Pupils' Perceptions of Teacher Racism in Their Context: A Case Study of Turkish and Belgian Vocational Education Pupils in a Belgian School

    Science.gov (United States)

    Stevens, Peter A. J.

    2008-01-01

    This article employs ethnographic data gathered from one Belgian (Flemish) secondary school to explore the meaning Belgian and Turkish-speaking minority pupils enrolled in technical and vocational education attach to teacher racism and racial discrimination, and to explore variations between pupils in making claims of teacher racism. A symbolic…

  9. IS OXYTOCIN A KEY HORMONE FOR GENE REGULATION AND PHYSIOLOGICAL FUNCTION IN POSTMENOPAUSAL WOMEN; AN INQUEST INTO POSSIBLE MECHANISMS?

    Directory of Open Access Journals (Sweden)

    Manoj G Tyagi

    2012-12-01

    Full Text Available Oxytocin (OT is a pituitary hormone and acts on the oxytocin receptor which are expressed in the brain, heart, kidney and blood vessels. OT has been implicated in its role in social bonding, and oxytocin's role in the parasympathetic nervous system includes the control of memory and learning processes and of various types of behaviour such as feeding, locomotion, as well as maternal and sexual behaviour. Oxytocin is also suggested to participate in the control of cardiovascular functions, thermoregulation, and pain threshold and fluid balance. Inefficient thermoregulation leads to hot flashes, and is associated with memory loss is a common symptom of menopause. Several studies suggest that the use of oxytocin and additional substances that amplify its effects can be used for treating weight changes, mood swings, hot flushes, somatic discomfort, dry and ulcerous mucous membranes, fissures, and bone loss during pre-menopause, menopause itself and post menopause. This review suggests its possible role in gene regulation and physiological function in post menopausal women and the possible mechanisms.

  10. Urinary isoflavonoids and risk of type 2 diabetes: a prospective investigation in US women.

    Science.gov (United States)

    Ding, Ming; Franke, Adrian A; Rosner, Bernard A; Giovannucci, Edward; van Dam, Rob M; Tworoger, Shelley S; Hu, Frank B; Sun, Qi

    2015-11-28

    To examine the association between urinary excretion of isoflavonoids and risk of type 2 diabetes (T2D), we conducted a nested case-control study among 1111 T2D pairs identified during 1995-2008 in the Nurses' Health Study (NHS) and NHSII, who were free of diabetes, CVD and cancer at urine sample collection. Urinary excretion of daidzein and genistein, as well as their metabolites O-desmethylangolensin (O-DMA), dihydrogenistein (DHGE) and dihydrodaidzein (DHDE) was assayed using liquid chromatography MS. Self-reported T2D incident cases were confirmed using a validated questionnaire. Higher urinary excretion of daidzein and genistein was associated with a lower risk of T2D in the combined cohorts. Comparing extreme tertiles of the urinary markers, the OR of T2D were 0·71 (95 % CI 0·55, 0·93) for daidzein and 0·74 (95 % CI 0·56, 0·97) for genistein, although the test for linear trend was not significant for genistein (P trend=0·03 and 0·15, respectively). DMA, DHDE and DHGE were non-significantly associated with a lower T2D risk. The inverse association of daidzein with T2D risk was stronger among post-menopausal women who did not use hormone replacement therapy (P interaction=0·001): the OR was 0·58 (95 % CI 0·34, 0·97) comparing extreme tertiles among these women. In conclusion, urinary excretion of isoflavones was associated with a lower T2D risk in US women, especially among post-menopausal women who did not use hormone. Further research is warranted to replicate these observations among western populations with similarly low overall isoflavone intake. PMID:26370252

  11. The Mandate System for the Belgian Public Prosecution

    Directory of Open Access Journals (Sweden)

    Bruno BROUCKER

    2009-12-01

    Full Text Available The law of 22 December 1998 introduced the mandate system for the heads of the Public Prosecution offices, which were appointed permanent before that. Theoretically, such a system needs to enhance, within the organization, effectiveness, efficiency, responsabilisation, and goal-orientation. However, the mandate system within the Belgian Public Prosecution was introduced prematurely, for dubious reasons and in a precipitate manner. In the current situation, the position of the mandate holder is uncertain, with a bounded autonomy and a low wage increase. Moreover, it remains impossible to intervene in the policy of appointed heads of office (during their mandate, the efficiency and effectiveness is only increased in some prosecution offices and a contract containing actual management responsibilities is absent. In sum: there is a large gap between the theoretical principles of mandate systems and the way it is introduced in the Belgian Public Prosecution.

  12. Management and Program Effectiveness in Belgian Sports Clubs

    OpenAIRE

    A. BALDUCK; M. BUELENS; Maes, M.

    2009-01-01

    This study investigated management and program effectiveness using the competing values approach as theoretical framework. The sample consisted of 823 board and sports members of Belgian sports clubs. Two scales were developed. Factor analysis revealed 12 management and 9 program effectiveness dimensions. Reliability scores were acceptable. Results showed that both board and sports members rated the dimension atmosphere at management and program level as the most effective factor in sports cl...

  13. Characteristics and challenges of the modern Belgian veal industry

    OpenAIRE

    Pardon, Bart; CATRY, Boudewijn; Boone, Randy; Theys, Hubert; De Bleecker, Koen; Dewulf, Jeroen; Deprez, Piet

    2014-01-01

    In this paper, the modern Belgian veal industry is situated in a European context, and an overview is provided of the major past, present and future challenges for veal production. The production of white veal requires a specific diet and housing conditions to assure a controlled iron anemic state resulting in pale carcasses. In response to the increasing public concern about animal welfare, legal limits for hemoglobin (in 1990), the provision of a minimum quality of solid feed to assure rumi...

  14. A survey of bacteria found in Belgian dairy farm products

    OpenAIRE

    N'Guessan, E.; Godrie, T.; de Laubier, J.; di Tanna, S.; Ringuet, M.; Sindic, M.

    2015-01-01

    Description of the subject. Due to the potential hazards caused by pathogenic bacteria, farm dairy production remains a challenge from the point of view of food safety. As part of a public program to support farm diversification and short food supply chains, farm dairy product samples including yogurt, ice cream, raw-milk butter and cheese samples were collected from 318 Walloon farm producers between 2006 and 2014. Objectives. Investigation of the microbiological quality of the Belgian dairy...

  15. Development path and capital structure of belgian biotechnology firms

    OpenAIRE

    Véronique Bastin; Albert Corhay; Georges Hübner; Pierre-Armand Michel

    2002-01-01

    This study investigates the relationship between the evolution of real options values and associated financing policies for Belgian companies in the sector of bio-industries. Each firm's situation regarding the relevant types of real options is stylistically represented through a scenario tree. The consumption of a time-to-build or a growth option is respectively considered as a success or a failure in company development. Empirically, several variables enable us to locate each company along ...

  16. A Belgian traveler who acquired yellow fever in The Gambia

    OpenAIRE

    Colebunders, R; Mariage, J. L.; Coche, J. C.; Pirenne, B; Kempinaire, S.; Hantson, P.; Gompel, A; Niedrig, M; Van Esbroeck, M.; Bailey, R; Drosten, C.; Schmitz, H

    2002-01-01

    A 47-year-old Belgian woman acquired yellow fever during a 1-week vacation in The Gambia; she had never been vaccinated against yellow fever. She died of massive gastrointestinal bleeding 7 days after the onset of the first symptoms. This dramatic case demonstrates that it is important for persons to be vaccinated against yellow fever before they travel to countries where yellow fever is endemic, even if the country, like The Gambia, does not require travelers to be vaccinated.

  17. Auditor Choice in the Belgian Nonprofit Sector: a Behavioral Perspective

    OpenAIRE

    REHEUL, Anne-Mie; Van Caneghem, Tom; Verbruggen, Sandra

    2011-01-01

    This study investigates auditor choice in Belgian nonprofit organizations from a behavioral perspective. We investigate whether auditor choice in favor of an auditor with a high (versus low) level of sector specialization is associated with the importance that nonprofit organizations attach to six auditor attributes: competence/integrity/deontology, working relationship with management, audit fee, practical execution of the audit, client oriented analysis and suggestions, and sector expertise...

  18. Internal finance and corporate investment: Belgian evidence with panel data

    OpenAIRE

    Barran, Fernando; Peeters, Marga

    1998-01-01

    In this paper the corporate investment decision under financial restrictions is investigated with Belgian firm data from 1984 to 1992. An investment Euler equation is derived from a dynamic optimization model with debt ceilings and an elastic credit supply. The model is estimated by GMM for different firm groups. An important aspect is that the sample is split according to a firm’s association with coordination centers. These centers have become the major external funding source of corpora...

  19. Dietary Intake of Artificial Sweeteners by the Belgian Population

    OpenAIRE

    Huvaere, Kevin; Vandevijvere, Stefanie Marie; Hasni, Moez; Vinkx, Christine; Van Loco, Joris

    2011-01-01

    Abstract In this study it was investigated whether the Belgian population older than 15 years was at risk of exceeding ADI levels of acesulfame-K, saccharin, cyclamate, aspartame, and sucralose through assessment of usual dietary intake of artificial sweeteners and specific consumption of table-top sweeteners. The conservative Tier 2 approach, for which an extensive label survey was performed, showed that mean usual intake was significantly lower than the respective ADIs for all sw...

  20. The Attitudes of Belgian Adolescents towards Peers with Disabilities

    OpenAIRE

    Bossaert, Goele; Colpin, Hilde; Pijl, Sip Jan; Petry, Katja

    2011-01-01

    This study aimed to explore Belgian adolescents' attitudes towards peers with disabilities and to explore factors associated with these attitudes. Based on the theory of persuasive communication, this study focused on receiver variables (the "whom"), characteristics of students with disabilities ("concerning who") and channel ("how"). An online survey was created and published on several popular websites for youngsters. Attitudes were assessed by means of the CATCH questionnair...

  1. Assessment of marine debris on the Belgian Continental Shelf

    OpenAIRE

    Van Cauwenberghe, L.; Claessens, M.; Vandegehuchte, M.B.; Mees, J.; Janssen, C. R.

    2013-01-01

    A comprehensive assessment of marine litter in three environmental compartments of Belgian coastal waters was performed. Abundance, weight and composition of marine debris, including microplastics, was assessed by performing beach, sea surface and seafloor monitoring campaigns during two consecutive years. Plastic items were the dominant type of macrodebris recorded: over 95% of debris present in the three sampled marine compartments were plastic. In general, concentrations of macrodebris wer...

  2. A survey of bacteria found in Belgian dairy farm products

    OpenAIRE

    N'Guessan, Elise; Godrie, Thérèse; De Laubier, Juliette; Ringuet, Mélanie; Sindic, Marianne

    2015-01-01

    Description of the subject. Due to the potential hazards caused by pathogenic bacteria, farm dairy production remains a challenge from the point of view of food safety. As part of a public program to support farm diversification and short food supply chains, farm dairy product samples including yogurt, ice cream, raw-milk butter and cheese samples were collected from 318 Walloon farm producers between 2006 and 2014. Objectives. Investigation of the microbiological quality of the Belgian da...

  3. Sustainable groundwater extraction in coastal areas: a Belgian example

    OpenAIRE

    Vandenbohede, A.; Van Houtte, E.; Lebbe, L.

    2009-01-01

    Water extractions in coastal areas have to deal with salt water intrusion and lowering of hydraulic heads in valuable ecosystems. Therefore, sustainable management of fresh water resources in these areas is crucial. This is illustrated here with two water extractions in the western Belgian coastal plain which extract groundwater from a phreatic dune aquifer. One water extraction faced problems with salt water intrusion, while lowering of hydraulic heads was an issue for both. To remedy the sa...

  4. 鲑鱼降钙素对绝经后骨质疏松性椎体骨折的治疗干预%EFFECTS OF SALMON CALCITONIN ON THE HEALING OF POST-MENOPAUSAL OSTEOPOROSIS AND VERTEBRAE FRACTURES OF THE FEMALE

    Institute of Scientific and Technical Information of China (English)

    钟俊; 刘世清

    2011-01-01

    Objectives: To probe the advangtages of treatment of post-menopausal osteoporosis vertebrae fractures with miacalcic. Methods: 97 patients of post-menopausal osteoporosis vertebrae fractures were selected to investigate the therapeutic effects of Miacalcic and compared with control group. Miacalcic group were treated with injecting Miacalcic 50IU/d on top of routine orthopedic treatment, and patients of control group were only treated with basic orthpaedic treatment. Results: A significant increase in serum bone glaprotein ( BGP) were found in Miacalcic group (t = 3.002, P < 0.01) and a significant decrease in urinary hydroxyproline/creatinine ratio (t = 7.21,P<0.01),as compared to the control after one month of treatment. The average time of fracture healing of Miacalcic group patients were shorter then that of control group. The back pain of Miacalcic group patients disappeared after four weeks of treatment. Conclusions: This study showed that Miacalcic was effective for the treatment of osteoporosis in post-menopausal female and beneficial to the healing of fracture and reducing the back pain.%目的:探讨女性绝经后骨质疏松性椎体骨折的鲑鱼降钙素治疗效果.方法:(1)选择2006年3月至2008年2月武汉大学人民医院骨科女性绝经后骨质疏松性椎体骨折患者97例.患者被随机分为2组:对照组44例,治疗组(鲑鱼降钙素组)53例.(2)两组患者均行卧硬板床、腰背部或胸背部垫软枕,口服钙尔奇D片等治疗.鲑鱼降钙素组在对照组干预措施基础上给予鲑鱼降钙素肌注,50IU/1次/d,连续1个月.(3)分别于治疗前、治疗后1个月采用放射免疫分析法测定血骨钙素、收集晨起第2次尿,偶氮三肿法测定尿钙、化学发光免疫分析法测定尿羟脯氨酸、碱性苦味酸法测定尿肌酐,并计算尿钙/尿肌酐与尿羟脯氨酸/尿肌酐比值.(4)开始治疗后4,6,8周复查脊柱X光正侧位片.了解骨折愈合情况.(5)分别与治疗后2、4周

  5. Hypnosis for hot flashes among postmenopausal women study: A study protocol of an ongoing randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Johnson Aimee K

    2011-10-01

    Full Text Available Abstract Background Hot flashes are a highly prevalent problem associated with menopause and breast cancer treatments. The recent findings from the Women's Health Initiative have important implications for the significance of a non-hormonal, mind-body intervention for hot flashes in breast cancer survivors. Women who take hormone therapy long-term may have a 1.2 to 2.0 fold increased risk of developing breast cancer. In addition, it is now known that hormone therapy with estrogen and progestin is associated with increased risk of cardiovascular disease and stroke. Currently there are limited options to hormone replacement therapy as non-hormonal pharmacological agents are associated with only modest activity and many adverse side effects. Because of this there is a need for more alternative, non-hormonal therapies. Hypnosis is a mind-body intervention that has been shown to reduce self-reported hot flashes by up to 68% among breast cancer survivors, however, the use of hypnosis for hot flashes among post-menopausal women has not been adequately explored and the efficacy of hypnosis in reducing physiologically measured hot flashes has not yet been determined. Methods/design A sample of 180 post-menopausal women will be randomly assigned to either a 5-session Hypnosis Intervention or 5-session structured-attention control with 12 week follow-up. The present study will compare hypnosis to a structured-attention control in reducing hot flashes (perceived and physiologically monitored in post-menopausal women in a randomized clinical trial. Outcomes will be hot flashes (self-report daily diaries; physiological monitoring; Hot Flash Related Daily Interference Scale, anxiety (State-Trait Anxiety Inventory; Hospital Anxiety and Depression Scale (HADS; anxiety visual analog scale (VAS rating; depression (Center for Epidemiologic Studies Depression Scale, sexual functioning (Sexual Activity Questionnaire, sleep quality (Pittsburgh Sleep Quality Index and

  6. Regional osteoporosis in western Sydney women

    International Nuclear Information System (INIS)

    Full text: Recently, 15% of elderly Japanese-American women have been shown to have marked heterogeneity of bone mineral density (BMD) between measured sites. The purposes of this study were to determine (1 ) the prevalence of this finding in an Australian population; and (2) potential association with clinical factors such as age, years since menopause (YSM), alcohol, smoking, family history, exercise, and body mass index. One hundred and fourteen peri-or post- menopausal Caucasian women (mean age 55 + 8.8 years) were referred for osteoporotic (OP) fracture risk assessment. Patients (pts) had no disorders or drugs known to affect BMD and no evidence of scoliosis or arthritic change. Bone densitometry of the lumbar spine (PA), hip and distal radius were measured using a Norland XR-26. According to WHO criteria, 30 pts (26%) were normal (T score > -1) at all sites; no pts (0%) had generalised OP (T score < -2.5); 29 (25%) had OP in one or two sites only (hip = 25, spine = 13, wrist = 1); the remaining 55 pts (48%) were osteogenic (-2.5 < T score < -1) in at least one site. Using multivariate logistic regression analysis, only YSM predicted regional OP (odds ratio = 1.14; p< O.001) Thus, clinically important heterogeneity of BMD occurs in about 25% of Western Sydney women; of clinical factors only YSM is independently associated with regional OP. Fracture risk classification may be improved by BMD measurement of multiple sites

  7. Crisis behind the figures? Belgian trade unions between strength, paralysis and revitalisation

    OpenAIRE

    Faniel, Jean

    2012-01-01

    Unlike most of the trade unions in European countries, Belgian unions managed to preserve a high and stable union density, and strong institutional positions. However, their situation is not blissful and the condition of both the workforce and the unions has been worsening for three decades. This article looks at the strengths and weaknesses of Belgian unions and presents four initiatives of union revitalisation recently developed. The argument is that Belgian unions do not fully size the sco...

  8. Risk analysis of marine activities in the Belgian part of the North Sea (RAMA): final report

    OpenAIRE

    Le Roy, D; Volckaert, A; Vermoote, S.; Wachter, B; Maes, F.; Coene, J.; Calewaert, J.-B.

    2006-01-01

    RAMA is a 2-year project (04/2004 - 04/2006) executed by two Belgian partners, Ecolas NV (Environmental Consultancy Agency) and the Maritime Institute (University of Ghent), and financed by the SPSD II research program, specific actions, of the Belgian Science Policy (BELPSO). RAMA aims to assess the environmental risks of spills by commercial shipping activities on the Belgian Part of the North Sea. Shipping patterns, transports of dangerous goods, probability of risks and the potential impa...

  9. Planning and implementation of the Belgian nuclear programme

    International Nuclear Information System (INIS)

    In the first part of the paper, the authors recall Belgian conditions, initially as regards primary energy (high degree of energy consumption and high degree of dependence on other countries), and then as regards electricity (divided up according to energy sources and types of producer). In the second part, the method used in Belgium for planning electrical power production is explained. Particular emphasis is placed on both the economic and technical assumptions made (trends in fuel costs, method of calculating investment costs, etc.). The development required, for the period 1982-92, of the means of production is stated in the light of the assumptions made. Fuel cycle planning (front and back ends) is also described with a review of the principal stages, namely supply of natural uranium, enrichment, reprocessing, treatment of irradiated fuel, and geological storage of wastes. The third and last part of the paper looks back at events in the implementation of the Belgian nuclear programme in chronological order. The beginnings of nuclear development in Belgium are recalled, as is the decision to construct the first three units (Doel 1, Doel 2 and Tihange 1), which were completed and put into service in 1975. The programme now under way is also briefly described, together with the characteristics of Belgian power stations, especially those concerned with safety. In conclusion, the paper outlines the main advantages of the nuclear option for a country as vulnerable where energy is concerned, as Belgium. (author)

  10. Aromatase inhibitors, efficacy and metabolic risk in the treatment of postmenopausal women with early breast cancer

    Directory of Open Access Journals (Sweden)

    Stefano Gonnelli

    2008-11-01

    Full Text Available Stefano Gonnelli1, Roberto Petrioli21Department of Internal Medicine, Endocrine-Metabolic Science and Biochemistry, University of Siena, Italy (Dir. R. Nuti.; 2Department of Human Pathology and Oncology, Medical Oncology Section, University of Siena, Italy (Dir. G. FranciniAbstract: The third-generation aromatase inhibitors (AIs, letrozole, anastrozole and exemestane, are becoming the first choice endocrine drugs for post-menopausal women with breast cancer, since they present greater efficacy when compared with tamoxifen in both adjuvant and metastatic setting. In particular, several large and well designed trials have suggested an important role for AIs in the adjuvant treatment of postmenopausal women with estrogen-receptor positive breast cancer either in the upfront, sequential or extended adjuvant mode. Overall, AIs are associated with a small but significant improvement in disease free survival. The expanding use of AIs in the treatment of early breast cancer means that individual patients will be exposed to the agents for longer durations, making it increasingly important to establish their long-term safety. This review focused on the effects of AIs on bone metabolism, serum lipids and cardiovascular risk. AIs have adverse effects on bone turnover with a reduction of bone mineral density and an increase in the rate of fragility fractures. With respect to tamoxifen AIs present lower thrombotic risk and a less favorable impact on lipid profile, whereas the true effects on cardiovascular risk still remain to be clarified. An adequate monitoring of bone mineral density (BMD and lipid profile could be recommended for post-menopausal women candidate to AIs.Keywords: breast cancer, aromatase inhibitors, bone loss, lipids, cardiovascular risk

  11. The Women's Health Questionnaire (WHQ: Frequently Asked Questions (FAQ

    Directory of Open Access Journals (Sweden)

    Hunter Myra S

    2003-09-01

    Full Text Available Abstract The Women's Health Questionnaire (WHQ is a measure of mid-aged women's emotional and physical health. Since its publication in 1992 the WHQ has been widely used in multinational clinical trials, in epidemiological studies as well as in the evaluation of non-medical treatments. In particular the WHQ has been included as a quality of life measure in trials of hormonal preparations for peri and post menopausal women and in studies using a variety of preventative interventions for mid-aged and older women. The questionnaire was developed in English and standardised on a sample of women aged 45–65 years. It is reliable, has good concurrent validity and is sensitive to detecting change, and is available in 27 languages. The range of subscales included in the WHQ enable a detailed assessment of dimensions of emotional and physical health, such as depression, anxiety, sleep problems, somatic symptoms, with optional subscales for menstrual problems and sexual difficulties. The WHQ is the first measure to be included in the MAPI Research Institute's database, the International Health-related Quality of Life Outcomes Database (IQOD. Drawing upon data from international studies this project aims to produce reference values for cross-culturally valid, reliable and responsive quality of life instruments. In addition to this work, a revised shorter version of the WHQ is currently being developed.

  12. Complete molar pregnancy in postmenopausal women.

    Science.gov (United States)

    Begum, Jasmina; Palai, Pallavee; Ghose, Seetesh

    2016-01-01

    Gestational trophoblastic disease (GTD) is an abnormal proliferation of trophoblastic tissue during pregnancy. It is a disease of reproductive age, and a few cases have also been seen in women with advanced age, although it is extremely rare in postmenopausal women. Here, we describe an uncommon case of complete hydatidiform mole (CHM) in a postmenopausal woman, who has presented to us with complaints of bleeding per vagina, vomiting with 22 weeks size gravid uterus. Ultrasound finding along with raised serum beta-human chorionic gonadotropin (β-HCG) 400,000 mIU/ml suggested the diagnosis of CHM. In view of postmenopausal status and future risk of postmolar gestational trophoblastic neoplasia, we performed a total abdominal hysterectomy. Uterus was 20 cm × 15 cm × 15 cm filled with cystic, grapes such as vesicles. Microscopic examination demonstrated generalized trophoblastic proliferation with hydropic degenerated villi suggested of benign CHM. Follow-up showed steady fall in serum β-HCG level and no evidence of any residual disease. A suspicion of GTD should be kept in mind while evaluating a patient with peri- or post-menopausal bleeding so that it will prevent a delay in diagnosis and treatment. PMID:27499598

  13. The Influence of the 1974 Oil Crisis on Sectoral Growth Rates in the Belgian Economy

    OpenAIRE

    F.BOSSIER; D. DUWEIN

    1981-01-01

    This paper briefly presents and analyses the behaviour of the different sectors of the Belgian economy during the period 1965-1978. Special attention is paid to the influence of the 1974 oil crisis on sectors of the Belgian economy. It is shown that the 1974 shock had different consequences according to the energy components of the sector

  14. REMOVABLE PARTIAL DENTURE MANAGEMENT ON POST-MENOPAUSE OSTEOPOROTIC FEMALE

    Directory of Open Access Journals (Sweden)

    Nina Ariani

    2015-06-01

    Full Text Available Osteoporosis is a condition of generalised skeletal fragility caused by diminishing bone amount and disturbance in bone microarchitecture with implication that the bone's ability to withstand forces is decreased. This condition leads to more bone resorption. Some researchers show that this condition also affects jaw bone. Therefore we must take this condition into consideration during prothodontic treatment. Dental prostheses are made to restore stomatognatic function as well as to preserve what was left including alveolar bone. The ability of dental prostheses to preserve residual alveolar bone differs according to type of prostheses. The case presented here propose the treatment of osteoporotic female in Prosthodontics Clinic FKG UI with removable partial denture. Considerations in selecting the type and design of dental prostheses and attempts to modify factors that might play a role in bone resorption in connection with the patient's physical and psychological status will be discussed. Thorough examination, careful planning and good communication with the patient can provide optimum results.

  15. Treatment of post-menopausal osteoporosis: beyond bisphosphonates.

    Science.gov (United States)

    Ishtiaq, S; Fogelman, I; Hampson, G

    2015-01-01

    Osteoporosis is a highly prevalent condition, characterized by compromised bone strength and fragility fractures and with an important associated socio-economic burden. Bisphosphonates are well established as the first line treatment for osteoporosis. However, while randomized control trials have in general demonstrated reasonable anti-fracture efficacy at the spine, they have shown moderate reduction in fracture incidence for non-vertebral sites. Furthermore, oral bisphosphonates are commonly associated with adverse gastrointestinal effects and both oral and parenteral bisphosphonates have been linked with osteonecrosis of the jaw and atypical femoral fracture, two rare but debilitating side effects. In addition, bisphosphonates are not recommended in patients with GFR odanacatib, a cathepsin K inhibitor and the anabolic agents, PTH analogue; PTH (1-34) and anti-sclerostin antibodies (activator of the Wnt pathway). Strontium ranelate will not be reviewed as recent reports highlight concerns surrounding its cardiovascular safety and together with an apparent increased risk of thrombosis, its future use remains uncertain. Some of these agents such as raloxifene, denosumab and teriparatide are already in clinical use whilst others are at varying stages of development. This review will provide an overview of the mechanisms of action of these therapeutic agents on the skeleton and assess their efficacy in osteoporosis and fracture prevention. PMID:25194424

  16. Thyroid-Stimulating Hormone (TSH Concentration at Birth in Belgian Neonates and Cognitive Development at Preschool Age

    Directory of Open Access Journals (Sweden)

    Caroline Trumpff

    2015-11-01

    Full Text Available The main objective of the study was to investigate the effect of MID during late pregnancy, assessed by the thyroid-stimulating hormone (TSH concentration at neonatal screening, on cognitive development of preschool children. A retrospective cohort study including 311 Belgian preschool children of 4–6 years old was conducted. Children were selected at random from the total list of neonates screened in 2008, 2009, and 2010 by the Brussels new-born screening center. Infants with congenital hypothyroidism, low birth weight, and/or prematurity were excluded from the selection. The selected children were stratified by gender and TSH-range (0.45–15 mIU/L. Cognitive abilities were assessed using Wechsler Preschool and Primary Scale of Intelligence—third edition. In addition, several socioeconomic, parental, and child confounding factors were assessed. Neonatal TSH concentration—a surrogate marker for MID—was not associated with Full Scale and Performance IQ scores in children. Lower Verbal IQ scores were found in children with neonatal TSH values comprised between 10–15 mIU/L compared to lower TSH levels in univariate analysis but these results did not hold when adjusting for confounding factors. Current levels of iodine deficiency among pregnant Belgian women may not be severe enough to affect the neurodevelopment of preschool children.

  17. Thyroid-Stimulating Hormone (TSH) Concentration at Birth in Belgian Neonates and Cognitive Development at Preschool Age.

    Science.gov (United States)

    Trumpff, Caroline; De Schepper, Jean; Vanderfaeillie, Johan; Vercruysse, Nathalie; Van Oyen, Herman; Moreno-Reyes, Rodrigo; Tafforeau, Jean; Vanderpas, Jean; Vandevijvere, Stefanie

    2015-11-01

    The main objective of the study was to investigate the effect of MID during late pregnancy, assessed by the thyroid-stimulating hormone (TSH) concentration at neonatal screening, on cognitive development of preschool children. A retrospective cohort study including 311 Belgian preschool children of 4-6 years old was conducted. Children were selected at random from the total list of neonates screened in 2008, 2009, and 2010 by the Brussels new-born screening center. Infants with congenital hypothyroidism, low birth weight, and/or prematurity were excluded from the selection. The selected children were stratified by gender and TSH-range (0.45-15 mIU/L). Cognitive abilities were assessed using Wechsler Preschool and Primary Scale of Intelligence-third edition. In addition, several socioeconomic, parental, and child confounding factors were assessed. Neonatal TSH concentration-a surrogate marker for MID-was not associated with Full Scale and Performance IQ scores in children. Lower Verbal IQ scores were found in children with neonatal TSH values comprised between 10-15 mIU/L compared to lower TSH levels in univariate analysis but these results did not hold when adjusting for confounding factors. Current levels of iodine deficiency among pregnant Belgian women may not be severe enough to affect the neurodevelopment of preschool children. PMID:26540070

  18. Differences between Belgian and Brazilian group A Streptococcus epidemiologic landscape.

    Directory of Open Access Journals (Sweden)

    Pierre Robert Smeesters

    Full Text Available BACKGROUND: Group A Streptococcus (GAS clinical and molecular epidemiology varies with location and time. These differences are not or are poorly understood. METHODS AND FINDINGS: We prospectively studied the epidemiology of GAS infections among children in outpatient hospital clinics in Brussels (Belgium and Brasília (Brazil. Clinical questionnaires were filled out and microbiological sampling was performed. GAS isolates were emm-typed according to the Center for Disease Control protocol. emm pattern was predicted for each isolate. 334 GAS isolates were recovered from 706 children. Skin infections were frequent in Brasília (48% of the GAS infections, whereas pharyngitis were predominant (88% in Brussels. The mean age of children with GAS pharyngitis in Brussels was lower than in Brasília (65/92 months, p<0.001. emm-typing revealed striking differences between Brazilian and Belgian GAS isolates. While 20 distinct emm-types were identified among 200 Belgian isolates, 48 were found among 128 Brazilian isolates. Belgian isolates belong mainly to emm pattern A-C (55% and E (42.5% while emm pattern E (51.5% and D (36% were predominant in Brasília. In Brasília, emm pattern D isolates were recovered from 18.5% of the pharyngitis, although this emm pattern is supposed to have a skin tropism. By contrast, A-C pattern isolates were infrequently recovered in a region where rheumatic fever is still highly prevalent. CONCLUSIONS: Epidemiologic features of GAS from a pediatric population were very different in an industrialised country and a low incomes region, not only in term of clinical presentation, but also in terms of genetic diversity and distribution of emm patterns. These differences should be taken into account for designing treatment guidelines and vaccine strategies.

  19. Cost-effectiveness of a 21-gene recurrence score assay versus Canadian clinical practice in women with early-stage estrogen- or progesterone-receptor-positive, axillary lymph-node negative breast cancer

    International Nuclear Information System (INIS)

    A 21-gene recurrence score (RS) assay may inform adjuvant systematic treatment decisions in women with early stage breast cancer. We sought to investigate the cost effectiveness of using the RS-assay versus current clinical practice (CCP) in women with early-stage estrogen- or progesterone-receptor-positive, axilliary lymph-node negative breast cancer (ER+/ PR + LN- ESBC) from the perspective of the Canadian public healthcare system. We developed a Markov model to project the lifetime clinical and economic consequences of ESBC. We evaluated adjuvant therapy separately in post- and pre-menopausal women with ER+/ PR + LN- ESBC. We assumed that the RS-assay would reclassify pre- and post-menopausal women among risk levels (low, intermediate and high) and guide adjuvant systematic treatment decisions. The model was parameterized using 7 year follow up data from the Manitoba Cancer Registry, cost data from Manitoba administrative databases, and secondary sources. Costs are presented in 2010 CAD. Future costs and benefits were discounted at 5%. The RS-assay compared to CCP generated cost-savings in pre-menopausal women and had an ICER of $60,000 per QALY gained in post-menopausal women. The cost effectiveness was most sensitive to the proportion of women classified as intermediate risk by the RS-assay who receive adjuvant chemotherapy and the risk of relapse in the RS-assay model. The RS-assay is likely to be cost effective in the Canadian healthcare system and should be considered for adoption in women with ER+/ PR + LN- ESBC. However, ongoing assessment and validation of the assay in real-world clinical practice is warranted

  20. Operating experience with diesel generators in Belgian nuclear power plants

    International Nuclear Information System (INIS)

    Various problems have occurred on the diesel generators in the Belgian nuclear power plants, independently of the D.G. manufacturer or from the operating crew. Furthermore no individual part of the D.G. can be incriminated as being the main cause of the incidents. The incidents reported in this paper are chosen because of the importance for the safety or for the long repair period. The unavailability of a D.G. can only be detected by periodic tests and controls. Combined with a good preventive maintenance, the risks of incidents can be reduced. (author)

  1. Internal capital market efficiency of Belgian holding companies

    OpenAIRE

    Gautier, Axel; Malika HAMADI

    2004-01-01

    In this paper, we raise the following two questions. (1) Do Belgian holding companies operate an internal capital market to transfer financial resources amongst their subsidiaries? And if yes, (2) is the internal capital market efficient? To answer the first question, we check if group cash flow is a determinant of the group members investment spending. The answer is positive if the holding company’s subsidiary is affiliated to a coordination center and negative otherwise. To ans...

  2. Migration and americanisation: The special case of Belgian economics.

    OpenAIRE

    Maes, Ivo; Buyst, Erik

    2005-01-01

    One of the distinguishing features of Belgian economics is that, from the early 1920s, so many of Belgium's best economists pursued postgraduate studies at top American universities, a case of ‘temporary’ migration. This was made possible by the fellowships granted by the Commission for Relief in Belgium, a legacy of the First World War. After a stay in the US of a few years, most returned to Belgium. However, they maintained strong links with the US. Also, they tried to recreate in Belgium t...

  3. Relationship Of FEF25-75, PEFR And SVC With Estrogen And Progesterone Level In Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Afroza Begum

    2011-12-01

    Full Text Available Background: Deterioration of lung function is common in women after menopause, which may be related to very low estrogen and progesterone level.Objective: To observe FEF25-75, PEFR and SVC (slow vital capacity values in apparently healthy postmenopausal women to find out their relationships with serum estrogen and progesterone.Methods: This study was carried out in the Department of Physiology in BSMMU, Dhaka in the year 2007. 30 healthy postmenopausal women aged 45 to 60 years and 30 healthy premenopausal women aged 20 to 30 years during their different phases of menstrual cycle were studied. Postmenopausal women were residents of Dhaka city and premenopausal subjects were medical students. FEF25-75, PEFR and SVC of all subjects were measured by a digital micro spirometer. Their estrogen and progesterone levels were estimated by Micro particle Enzyme Immunoassay (MEIA method. Data were analyzed by Pearson’s correlation coefficient test, one way ANOVA and unpaired‘t’ testResults: The mean percentage of predicted values of FEF25-75 and PEFR were lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women but it was not significant. Measured values of SVC was Significantly (p<.001 lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women. Again Mean serum estrogen and progesterone levels were significantly (p<.001 lower in post menopausal women compared to those of follicular and luteal phases of premenopausal women. In post menopausal women, FEF25-75 was positively, PEFR and SVC were negatively correlated with progesterone level. PEFR and SVC showed positive correlattion and FEF25-75 showed negative correlation with serum estrogen level. All these correlations were statistically non significant. In premenopausal women FEF25-75 and PEFR showed positive correlation and SVC showed negative correlation with serum progesterone level. The relationships were

  4. Pyrrolizidine alkaloids in food and feed on the Belgian market.

    Science.gov (United States)

    Huybrechts, Bart; Callebaut, Alfons

    2015-01-01

    Pyrrolizidine alkaloids (PAs) are widely distributed plant toxins with species dependent hepatotoxic, carcinogenic, genotoxic and pneumotoxic risks. In a recent European Food Safety Authority (EFSA) opinion, only two data sets from one European country were received for honey, while one feed data set was included. No data are available for food or feed samples from the Belgian market. We developed an LC-MS/MS method, which allowed the detection and quantification of 16 PAs in a broad range of matrices in the sub ng g(-1) range. The method was validated in milk, honey and hay and applied to honey, tea (Camellia sinensis), scented tea, herbal tea, milk and feed samples bought on the Belgian market. The results confirmed that tea, scented tea, herbal tea and honey are important food sources of pyrrolizidine alkaloid contamination in Belgium. Furthermore, we detected PAs in 4 of 63 commercial milk samples. A high incidence rate of PAs in lucerne (alfalfa)-based horse feed and in rabbit feed was detected, while bird feed samples were less contaminated. We report for the first time the presence of monocrotaline, intermedine, lycopsamine, heliotrine and echimidine in cat food. PMID:26373269

  5. The attitudes of Belgian adolescents towards peers with disabilities.

    Science.gov (United States)

    Bossaert, Goele; Colpin, Hilde; Pijl, Sip Jan; Petry, Katja

    2011-01-01

    This study aimed to explore Belgian adolescents' attitudes towards peers with disabilities and to explore factors associated with these attitudes. Based on the theory of persuasive communication, this study focused on receiver variables (the "whom"), characteristics of students with disabilities ("concerning who") and channel ("how"). An online survey was created and published on several popular websites for youngsters. Attitudes were assessed by means of the CATCH questionnaire among 167 adolescents between 11 and 20 years old. Univariate and multivariate regression analyses were conducted. Belgian adolescents had fairly tolerant attitudes towards peers with disabilities. Factors associated with more positive attitudes were being female, and viewing a video introduction of a peer with a disability before assessing attitudes. Factors such as having a parent, sibling or good friend with a disability and frequent contact with persons with disabilities did not remain significant in the overall model. The way in which students with disabilities are presented to their peers is very important. Further research is needed among larger samples, including more diverse variables, concerning the former mentioned categories, and also concerning the source (the "who") and message (the "what"). PMID:21257288

  6. Total reflection X-ray fluorescence analysis of oral fluids of women affected by osteoporosis and osteopenia

    International Nuclear Information System (INIS)

    Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures; the early stage of decreased bone density is called osteopenia. More than 200 million people are affected and about 50% of post-menopausic women are expected to develop the disease. Osteoporosis, osteopenia and periodontal disease have in common several risk factors, being hyperthyroidism and smoking habits the most important ones. There is scarce information in the literature about the association between periodontal disease and osteoporosis and/or osteopenia. Some works suggest that osteoporotic women are susceptible to a higher loss of periodontal insertion, alveolar bones, and teeth. Thirty adult post-menopausic women were studied; some of them were healthy (control group) and the rest of them were undergoing some stage of osteoporosis or osteopenia. All the subjects were healthy, non-smokers, not having dental implants, and with communitarian periodontal index higher than 1(CPI > 1). Samples of saliva and gingival crevice fluid were extracted with calibrated micro-capillaries and deposited on Si reflectors. Known amounts of Ga were added to the samples in order to act as internal standard for quantification by the total reflection x-ray fluorescence technique. Experimental concentrations of several elements (P, S, Cl, K, Ca, Cr, Fe, NI, Cu, and Zn) were determined. The concentration of some elements in saliva showed different behavior as compared to gingival crevice fluid. Some critical elements of bone composition, such as Ca and Zn, present very distinguishable behavior. Improvements in the statistics are required for a better assessment of a routine method and to establish some correlation with periodontal disease. TXRF seems to be a promising method to evaluate the evolution of osteoporosis

  7. Total reflection X-ray fluorescence analysis of oral fluids of women affected by osteoporosis and osteopenia

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, Hector Jorge [Facultad de Matematica Astronomia y Fisica, Universidad Nacional de Cordoba, 5000 Cordoba (Argentina)], E-mail: jsan@famaf.unc.edu.ar; Valentinuzzi, Maria Cecilia [Facultad de Matematica Astronomia y Fisica, Universidad Nacional de Cordoba, 5000 Cordoba (Argentina); Grenon, Miram [Facultad de Odontologia, Universidad Nacional de Cordoba, 5000 Cordoba (Argentina); Abraham, Jose [Facultad de Matematica Astronomia y Fisica, Universidad Nacional de Cordoba, 5000 Cordoba (Argentina)

    2008-12-15

    Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures; the early stage of decreased bone density is called osteopenia. More than 200 million people are affected and about 50% of post-menopausic women are expected to develop the disease. Osteoporosis, osteopenia and periodontal disease have in common several risk factors, being hyperthyroidism and smoking habits the most important ones. There is scarce information in the literature about the association between periodontal disease and osteoporosis and/or osteopenia. Some works suggest that osteoporotic women are susceptible to a higher loss of periodontal insertion, alveolar bones, and teeth. Thirty adult post-menopausic women were studied; some of them were healthy (control group) and the rest of them were undergoing some stage of osteoporosis or osteopenia. All the subjects were healthy, non-smokers, not having dental implants, and with communitarian periodontal index higher than 1(CPI > 1). Samples of saliva and gingival crevice fluid were extracted with calibrated micro-capillaries and deposited on Si reflectors. Known amounts of Ga were added to the samples in order to act as internal standard for quantification by the total reflection x-ray fluorescence technique. Experimental concentrations of several elements (P, S, Cl, K, Ca, Cr, Fe, NI, Cu, and Zn) were determined. The concentration of some elements in saliva showed different behavior as compared to gingival crevice fluid. Some critical elements of bone composition, such as Ca and Zn, present very distinguishable behavior. Improvements in the statistics are required for a better assessment of a routine method and to establish some correlation with periodontal disease. TXRF seems to be a promising method to evaluate the evolution of osteoporosis.

  8. Total reflection X-ray fluorescence analysis of oral fluids of women affected by osteoporosis and osteopenia

    Science.gov (United States)

    Sánchez, Héctor Jorge; Valentinuzzi, María Cecilia; Grenón, Miram; Abraham, José

    2008-12-01

    Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures; the early stage of decreased bone density is called osteopenia. More than 200 million people are affected and about 50% of post-menopausic women are expected to develop the disease. Osteoporosis, osteopenia and periodontal disease have in common several risk factors, being hyperthyroidism and smoking habits the most important ones. There is scarce information in the literature about the association between periodontal disease and osteoporosis and/or osteopenia. Some works suggest that osteoporotic women are susceptible to a higher loss of periodontal insertion, alveolar bones, and teeth. Thirty adult post-menopausic women were studied; some of them were healthy (control group) and the rest of them were undergoing some stage of osteoporosis or osteopenia. All the subjects were healthy, non-smokers, not having dental implants, and with communitarian periodontal index higher than 1(CPI > 1). Samples of saliva and gingival crevice fluid were extracted with calibrated micro-capillaries and deposited on Si reflectors. Known amounts of Ga were added to the samples in order to act as internal standard for quantification by the total reflection x-ray fluorescence technique. Experimental concentrations of several elements (P, S, Cl, K, Ca, Cr, Fe, NI, Cu, and Zn) were determined. The concentration of some elements in saliva showed different behavior as compared to gingival crevice fluid. Some critical elements of bone composition, such as Ca and Zn, present very distinguishable behavior. Improvements in the statistics are required for a better assessment of a routine method and to establish some correlation with periodontal disease. TXRF seems to be a promising method to evaluate the evolution of osteoporosis.

  9. Legacy of Colonialism in the Empowerment of Women in Rwanda

    OpenAIRE

    Ilaria Buscaglia; Shirley Randell

    2012-01-01

    The empowerment of women in Rwanda is rooted in colonial times. In the second half of the 1940s, the Belgian administration, together with religious missionaries, started some educational and social welfare programs for women, known as the foyers sociaux (social homes). This paper explores how this program of female promotion and its progeny affected the domestication of Rwandan women, what caused the situation to change following the genocide against the Tutsi in 1994, and what more might be...

  10. An Actigraphy Study of Sleep and Pain in Midlife Women – The SWAN Sleep Study

    Science.gov (United States)

    Kravitz, Howard M.; Zheng, Huiyong; Bromberger, Joyce T.; Buysse, Daniel J.; Owens, Jane; Hall, Martica H.

    2014-01-01

    Objective We examined whether women reporting nighttime pain would have more actigraphy-measured evidence for disturbed sleep and report feeling less rested compared to women without nighttime pain. Methods Up to 27 consecutive nights of actigraphy and sleep diary data were analyzed from each participant in this community-based study of 314 African-American (n=118), White (n=141), and Chinese (n=55) women, aged 48-58 years, who were pre-, peri- or post-menopausal and participating in the Study of Women's Health Across the Nation (SWAN) Sleep Study. Dependent variables were actigraphy-measured movement and fragmentation index, total sleep time, and sleep efficiency, and diary self-report of feeling rested after waking up. All outcomes were fit using linear mixed effect models to examine covariate-adjusted associations between the independent variable, nighttime pain severity, and sleep outcomes. Results Higher pain severity scores were associated with longer sleep duration but reduced sleep efficiency and feeling less rested. Women reporting nocturnal vasomotor symptoms had more sleep-related movement and sleep fragmentation, reduced sleep efficiency, and were less likely to feel rested after wakening, regardless of whether they reported pain. Conclusions Midlife women who report higher nighttime pain levels have more objective evidence for less efficient sleep, consistent with self-reported less restful sleep. Nocturnal vasomotor symptoms also can contribute to restlessness and wakefulness in midlife women. PMID:25706182

  11. STUDY OF SERUM TOTAL CALCIUM, IO NIZED CALCIUM AND TOTAL PROTEIN CONCENTRATIONS IN POSTMENOPAUSAL WOMEN

    Directory of Open Access Journals (Sweden)

    SK.Deepthi

    2015-05-01

    Full Text Available Menopause and ageing is associated with accelerated loss of cortical bone. Osteoporotic fractures are common cause of morbidity and mortality in adult Indian women due to ageing. This study was conducted to evaluate the levels of serum calcium, ionized calcium and total protein levels in postmenopausal women and to assess its relation with ageing. Study includes 70 women (40 post menopausal and 30 prem enopausal women serum alkaline phosphatase, serum calcium, ionized calcium and total proteins, serum albumin were estimated in both cases and controls. There is decrease in serum calcium in postmenopausal; wo men when compared to premenopausal women. There was no significant change in ionized calcium in both cases and controls. ALP is highly significant P<0.001. In postmenopausal women suggesting there is high alkaline phosphotase activity in postmenopausal women as a result of the inhibitory effects of estrogen on bone turnover rate which is dependent on age and body mass index. Decrease in serum albumin was seen in postmenopausal wo men which is the reason for decrease in serum calcium level which is inturn related to ageing effect.

  12. Annual report for the steering committee of the association Euratom-Belgian State for fusion 1999

    International Nuclear Information System (INIS)

    This report is prepared for the annual steering committee meting of the Association Euratom - Belgian State in the area of fusion reactor technology. The Belgian contribution focuses on the assessment of the first wall and blanket materials under radiation and coolant interaction and on developments for the remote handling in maintenance activities. The period October 1998 to September 1999 is reported on.The fusion technology work performed at the Belgian Nuclear Research Centre SCK/CEN, the Department of Metallurgy and Materials Engineering of the Louvain University (Belgium) and S.A. Gradel, a Luxemburg-based organisation, is described

  13. Annual report for the steering committee of the association Euratom-Belgian State for fusion 1998

    International Nuclear Information System (INIS)

    This report is prepared for the annual steering committee meting of the Association Euratom - Belgian State in the area of fusion reactor technology. The Belgian contribution focuses on the assessment of the first wall and blanket materials under radiation and coolant interaction and on developments for the remote handling in maintenance activities. The period October 1997 to September 1998 is reported on.The fusion technology work performed at the Belgian Nuclear Research Centre SCK/CEN, the Department of Metallurgy and Materials Engineering of the Louvain University (Belgium) and S.A. Gradel, a Luxemburg-based organisation, is described

  14. Annual report for the steering committee of the association Euratom-Belgian State for fusion 1999

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    1999-10-01

    This report is prepared for the annual steering committee meting of the Association Euratom - Belgian State in the area of fusion reactor technology. The Belgian contribution focuses on the assessment of the first wall and blanket materials under radiation and coolant interaction and on developments for the remote handling in maintenance activities. The period October 1998 to September 1999 is reported on.The fusion technology work performed at the Belgian Nuclear Research Centre SCK/CEN, the Department of Metallurgy and Materials Engineering of the Louvain University (Belgium) and S.A. Gradel, a Luxemburg-based organisation, is described.

  15. Assessment of the acrylamide intake of the Belgian population and the effect of mitigation strategies

    OpenAIRE

    Claeys, Wendie Liliane; Baert, Katleen; Mestdagh, Frédéric; Vercammen, Jan; Daenens, Paul; Meulenaer, Bruno De; Maghuin-Rogister, Guy; Huyghebaert, André

    2010-01-01

    Abstract The acrylamide (AA) intake of the Belgian consumer was calculated based on AA monitoring data of the Belgian Federal Agency for the Safety of the Food Chain (FASFC) and consumption data of the Belgian food consumption survey coordinated by the Scientific Institute for Public Health (3214 participants of 15 years or older). The average AA exposure, calculated probabilistically, was 0.4 ?g/kg bw/day (P97.5 = 1.6 ?g/kg bw/day) with as main contributors to the average intake c...

  16. Severe Accident Management Measures Introduced in Belgian NPP's

    International Nuclear Information System (INIS)

    In response to the Belgian Safety Authorities' request to address the severe accident issue within a decennial safety review, Tractebel, on behalf of the Belgian Utility, Electrabel, examined in detail specific severe accident topics and provided the Utility with several measures that could be implemented to reduce the risk associated with beyond-design accidents. The present paper summarizes the key elements of the approach applied in Belgium: - Presentation of plant-specific studies related to severe accident issues; - Use of PSA results; - Inputs of international R and D projects; - Selection and justification of severe accident measures; - Comparative study between possible mitigative measures; - Definition and justification of implemented severe accident management strategies. The vulnerability to severe accidents as well as the potential causes of containment failures have been identified leading to the study of possible countermeasures taking into account the combination of conservative design and post-TMI measures already implemented . A section of the paper will also be devoted to the specific study made for the selection, the sizing and the implementation of hydrogen control means. After the description of the selected measures implemented, the paper also describes the content of the 'Severe Accident Management Guidelines' developed by Tractebel for the Tihange NPPs and for the Doel NPPs. This project aimed at providing the operators with procedures or guidelines enabling to deal with complex situations not formally considered in the standard Emergency Response Guidelines, including accidents in which a significant portion of the core melts. The objective of these SAMG's programs is to indicate actions that must bring the plant to a controlled stable state and, above all, mitigate any challenges to the fission product barriers. The plant personnel must use the available plant information to determine the best severe accident management measures. Obviously

  17. Newspaper Coverage of Women's Sports during the 2000 Sydney Olympic Games: Belgium, Denmark, France, and Italy

    Science.gov (United States)

    Capranica, Laura; Minganti, Carlo; Billat, Veronique; Hanghoj, Signe; Piacentini, Maria Francesca; Cumps, Elke; Meeusen, Romain

    2005-01-01

    In general, women are well represented among sport participants and sport audiences but not in the media. Data show that women's sport is greatly under-reported and trivialized in newspapers. Therefore, the purpose of this study was to measure press coverage during the 2000 Summer Olympic Games in the largest circulating Belgian, Danish, French,…

  18. Digital radiographic equipment in the Belgian dental office.

    Science.gov (United States)

    Gijbels, F; Debaveye, D; Vanderstappen, M; Jacobs, R

    2005-01-01

    A survey was performed among Belgian dentists to evaluate the use and management of digital radiographic equipment. The majority of respondents work as general dental practitioners. One out of eight sets of equipment for extraoral exposures is digital. For intraoral radiography, 30% of the equipment is digital. While exposure time is reduced by about 50% for digital intraoral radiography compared with conventional radiography, no differences can be found between different conventional film speed classes. Appropriate collimation of the radiation beam is only sparingly used. Beam aiming devices to hold the film and position the radiation beam are not used by the majority of dentists. While 25% of the respondents stand behind a protective wall during exposure, 8% of dentists remain next to the patient during exposure while assisting in holding the film inside the mouth. A minority of the latter practitioners wear lead aprons. PMID:16461489

  19. Characteristics of suicide hotspots on the Belgian railway network.

    Science.gov (United States)

    Debbaut, Kevin; Krysinska, Karolina; Andriessen, Karl

    2014-01-01

    In 2004, railway suicide accounted for 5.3% of all suicides in Belgium. In 2008, Infrabel (Manager of the Belgian Railway Infrastructure) introduced a railway suicide prevention programme, including identification of suicide hotspots, i.e., areas of the railway network with an elevated incidence of suicide. The study presents an analysis of 43 suicide hotspots based on Infrabel data collected during field visits and semi-structured interviews conducted in mental health facilities in the vicinity of the hotspots. Three major characteristics of the hotspots were accessibility, anonymity, and vicinity of a mental health institution. The interviews identified several risk and protective factors for railway suicide, including the training of staff, introduction of a suicide prevention policy, and the role of the media. In conclusion, a comprehensive railway suicide prevention programme should continuously safeguard and monitor hotspots, and should be embedded in a comprehensive suicide prevention programme in the community. PMID:24020492

  20. Can Belgian nuclear power stations work for longer?

    International Nuclear Information System (INIS)

    In 2008 Paul Magnette, former Minister of Climate and Energy, requested the GEMIX Commission - a team of Belgian and international energy specialists - to examine the energy future of Belgium. Within this framework, it was planned to examine ideal energy mixes to ensure the energy supplies of Belgium, to secure our competitive position and to ensure that environmental and climate objectives are achieved. In the framework of this study, the GEMIX Commission asked SCK-CEN to evaluate the lifetime of the commercial nuclear power plants at Doel and Tihange. In particular, the Commission wanted to know whether it is technically feasible and safe to keep these power plants open for longer than 40 years, the lifetime stipulated in the 2003 Nuclear Energy Extrication Act. The article gives a summary overview of the expert opinion of SCK-CEN to the Gemix Commission.

  1. Belgian Workshop (November 2003) - Executive Summary and International Perspective

    International Nuclear Information System (INIS)

    The fourth workshop of the OECD/NEA Forum on Stakeholder Confidence (FSC) was hosted by ONDRAF/NIRAS, the Belgian Agency for Radioactive Waste Management and enriched fissile materials. The central theme of the workshop was 'Dealing with interests, values and knowledge in managing risk' within the Belgian context of local partnerships for the long term management of low-level, short-lived radioactive waste. The four-day workshop started with a half-day session in Brussels giving a general introduction on the Belgian context and the local partnership methodology. This was followed by community visits to three local partnerships, PaLoFF in Fleurus-Farciennes, MONA in Mol, and STOLA in Dessel. After the visits, the workshop continued with two full-day sessions in Brussels. One hundred and nineteen registered participants, representing 13 countries, attended the workshop or participated in the community visits. About two thirds were Belgian stakeholders; the remainder came from FSC member organisations. The participants included representatives of municipal governments, civil society organisations, government agencies, industrial companies, the media, and international organisations as well as private citizens, consultants and academics. The four-day meeting was structured as follows: Day 1 morning was devoted to introductory presentations. Information was given on the general radioactive waste management context in Belgium. Regarding the management of LLW, and in particular the search for a disposal facility site, the workshop heard about the local partnership methodology developed by university researchers of the University of Antwerp and the Fondation Universitaire Luxembourgeoise (FUL). These partnerships between the potential host municipalities and the radwaste agency have the mission to develop an integrated facility proposal adapted to local conditions. Community visits took place on Day 1 afternoon and Day 2. Visits offered an opportunity for

  2. Dietary intake of artificial sweeteners by the Belgian population.

    Science.gov (United States)

    Huvaere, Kevin; Vandevijvere, Stefanie; Hasni, Moez; Vinkx, Christine; Van Loco, Joris

    2012-01-01

    This study investigated whether the Belgian population older than 15 years is at risk of exceeding ADI levels for acesulfame-K, saccharin, cyclamate, aspartame and sucralose through an assessment of usual dietary intake of artificial sweeteners and specific consumption of table-top sweeteners. A conservative Tier 2 approach, for which an extensive label survey was performed, showed that mean usual intake was significantly lower than the respective ADIs for all sweeteners. Even consumers with high intakes were not exposed to excessive levels, as relative intakes at the 95th percentile (p95) were 31% for acesulfame-K, 13% for aspartame, 30% for cyclamate, 17% for saccharin, and 16% for sucralose of the respective ADIs. Assessment of intake using a Tier 3 approach was preceded by optimisation and validation of an analytical method based on liquid chromatography with mass spectrometric detection. Concentrations of sweeteners in various food matrices and table-top sweeteners were determined and mean positive concentration values were included in the Tier 3 approach, leading to relative intakes at p95 of 17% for acesulfame-K, 5% for aspartame, 25% for cyclamate, 11% for saccharin, and 7% for sucralose of the corresponding ADIs. The contribution of table-top sweeteners to the total usual intake (sucralose: 3.08 versus 3.03, expressed as mg kg(-1) bodyweight day(-1) at p95) showed that the latter group was not exposed to higher levels. It was concluded that the Belgian population is not at risk of exceeding the established ADIs for sweeteners. PMID:22088137

  3. Belgian nuclear power life extension and fuss about nuclear rents

    International Nuclear Information System (INIS)

    Nuclear decision-making is embedded in slowly evolving political, economic and financial institutions. Belgium houses extended nuclear activities, mostly under French control, for example: SUEZ-GDF and EDF own all Belgian nuclear power plants. But a 2003 law mandates the closure of Belgium's nuclear power plants at a service age of 40 years; only force majeure could lift the strict obligation. Opposition to the law argued with climate change danger, financial losses, and loss-of-load risks. The financial issue got interwoven with a fuzzy debate on the definition, height and appropriation of “nuclear rents”. As plausible hypothesis is adopted: the prospected transfer of hundreds millions of euro from power companies to the public interest will create public support for life extension. But the nuclear rents discussion had faded in July 2012 when the Belgian government admitted a 10-year life extension for TIHANGE I (962 MW) and imposed the closure of the 2×433 MW DOEL I and II. Loss-of-load risk was the government's only public argument. The opacity of the decision process and its “fifty–fifty” outcome do not allow proper testing of the hypothesis. The case illustrates that politicians cannot bind their followers except through the deployment of alternative power sources. - Highlights: • Nuclear phase-out is only successful when alternative supplies are deployed. • Politicians cannot bind their successors by words or by lawgiving. • The phase-out law exemplifies the disruption of a strong nuclear lock-in. • Life extension exemplifies the disruption of the phase-out law. • The impact of imprecise nuclear rents on life extension could not be tested

  4. Risk Factors for Spinal Osteoporosis As Compared with Femoral Osteoporosis in Urban Iranian Women

    Directory of Open Access Journals (Sweden)

    H Adibi

    2012-10-01

    Full Text Available Background: We aimed to define and compare the risk factors of spinal and femoral osteoporosis in postmenopausal Iranian women.Method: It was a multicentre based study carried out in two stages during 2002 to 2005 among post menopausal women in Tehran. In first stage case group included 140 women with diagnosed spinal osteoporosis using DEXA method as definition of WHO and Controls were 167 women with normal spinal BMD. In second stage, among thesame study population case groups were 72 women with total femoral neck osteoporosis. The controls included 191 women with normal femoral BMD.` Odds Ratio was used for estimation the association of risk factors with spinal and femoral osteoporosis.Results: Plus common well known osteoporosis risk factors,significant risk factors for each region with their oddsratios included: Steroid use (2.4 and low activity (3.6 for femoral osteoporosis and parity>3 (2 and lactation duration> 2 yr (1.9 for spinal osteoporosis.Conclusions: There are some common and different protective and risk factors for spinal and femoral osteoporosis in this population.

  5. Assessment of doses received by the Belgian population due to the Chernobyl releases

    International Nuclear Information System (INIS)

    The consequences of the exposure during the first year and beyond the first year after the Chernobyl accident in terms of radiation effects on the Belgian population are discussed as well as some uncertainties in these evaluations. (A.F.)

  6. The Labour Market as the Driving Force of Belgian Higher Education.

    Science.gov (United States)

    Wielemans, Willy

    1988-01-01

    An examination of internal and external forces on Belgian higher education suggests that the system is too closely controlled by economic and political forces in the labor market, which threatens to distort university life and higher education in general. (MSE)

  7. MERIS imagery of Belgian coastal waters: mapping of suspended particulate matter and chlorophyll-a

    OpenAIRE

    Ruddick, K.; PARK, Y.; B. Nechad

    2003-01-01

    This paper describes a first application-oriented analysis of MERIS products for Suspended Particulate Matter (SPM) and Chlorophyll-a (CHL) concentration in Belgian coastal waters. Regional algorithms designed for Belgian waters have been implemented and compared with the standard MERIS products, termed Total Suspended Matter and Algal2 respectively. The standard and regional SPM products seem robust and give similar data. Notwithstanding a more complete match-up validation analysis, these pr...

  8. Working Paper 13-09 - Qualitative Employment Multipliers for the Belgian Environmental Industry

    OpenAIRE

    Adja Awa Sissoko; Bart Van den Cruyce

    2009-01-01

    The present paper computes cumulative employment generated by the Belgian environmental industry. Relying on Belgian input-output tables for the year 2000 and on detailed employment data (SAM sub ]matrix), we investigate the patterns of the employment in the environmental industry, by considering the worker types differentiated by gender, educational attainment or a combination of these characteristics. The employment multiplier analysis of environmental employment reveals some interesting di...

  9. Compliance of Companies with Corporate Governance Codes: Case Study on Listed Belgian

    OpenAIRE

    Sven H. De Cleyn

    2014-01-01

    Listed and large companies become increasingly subject to internal and external pressure to comply with ethical and social standards. This article focuses on one aspect of this matter, namely the corporate governance issue. Within the framework of recent corporate scandals, this paper investigates whether and to which extent Belgian publicly listed SMEs comply with the Belgian Code on Corporate Governance after its first year of introduction, which has been constituted in the framework of the...

  10. A nationwide Hospital Survey on Patient Safety Culture in Belgian Hospitals: Analysis and Benchmarking

    OpenAIRE

    Vlayen, Annemie; Hellings, Johan; Claes, Neree; Schrooten, Ward

    2010-01-01

    Objective To measure patient safety culture in Belgian hospitals and to examine the homogeneous grouping of underlying safety culture dimensions. Methods The Hospital Survey on Patient Safety Culture was distributed organisation-wide in 180 Belgian hospitals participating in the federal program on quality and safety between 2007 and 2009. Participating hospitals were invited to submit their data to a comparative database. Homogeneous groups of underlying safety culture dimensions were sou...

  11. Annual report for the steering committee of the association Euratom-Belgian State for fusion 1996

    Energy Technology Data Exchange (ETDEWEB)

    Moons, F.; Bogaerts, W.; Decreton, M.; Biver, E.; Coenen, S.; Benoit, Ph.; Coheur, L.; Deboodt, P.; Andreev, D.

    1996-09-01

    This report is prepared for the annual steering committee meting of the Association Euratom - Belgian State for Fusion. The period October 1995 to September 1996 is reported on.The fusion technology work performed at the Belgian Nuclear Research Centre SCK/CEN, the Department of Metallurgy and Materials Engineering of the Louvain University (Belgium) and S.A. Gradel, a Luxemburg company, is described.

  12. impact of six multimodal country-wide campaigns to promote hand hygiene in belgian hospitals

    OpenAIRE

    Fonguh, Sylvanus; Hammami, N; Catry, B; Simon, Anne; ICPIC

    2015-01-01

    Six campaigns sponsored by the Belgian federal government were organized to promote hand hygiene(HH) in Belgian hospitals between 2005 and 2015. The campaigns combined educational sessions for healthcare workers (HCWs), promotion of alcohol-based hand rubs, patient awareness and audits with performance feedback. Each campaign consisted of a pre-campaign data collection period, an awareness period with training and a post-campaign data collection period.

  13. BNAIC 2008: Proceedings 20th Belgian-Netherlands Conference on Artificial Intelligence

    OpenAIRE

    Nijholt, Anton; Pantic, Maja; Poel, Mannes; Hondorp, Hendri

    2008-01-01

    This book contains the proceedings of the 20th edition of the Belgian-Netherlands Conference on Artificial Intelligence. The conference was organized by the Human Media Interaction group of the University of Twente. As usual, the conference was under the auspices of the Belgian-Dutch Association for Artificial Intelligence (BNVKI) and the Dutch Research School for Information and Knowledge Systems (SIKS). The conference aims at presenting an overview of state-of-the-art research in artificial...

  14. Annual report for the steering committee of the association Euratom-Belgian State for fusion 1996

    International Nuclear Information System (INIS)

    This report is prepared for the annual steering committee meting of the Association Euratom - Belgian State for Fusion. The period October 1995 to September 1996 is reported on.The fusion technology work performed at the Belgian Nuclear Research Centre SCK/CEN, the Department of Metallurgy and Materials Engineering of the Louvain University (Belgium) and S.A. Gradel, a Luxemburg company, is described

  15. A study on hormonal control of calcium homeostasis in egyptian women

    International Nuclear Information System (INIS)

    This investigation was conducted to study the possible role of circulating hormones that regulate the calcium flux, in addition to serum levels of the inorganic mineral contents, calcium and phosphorus, on the pathogenesis of post-menopausal osteoporosis in egyptian women. The investigation studied also the response of these variables to both of estradiol withdrawal and age progress. Five groups of 11 postmenopausal osteoporotic (mean age 73 -+ 2.3 years), 26 postmenopausal women (mean age 56.2 -+ 2.4 years), 17 premenopausal women (mean age 48.8 -+ 0.7 years), 26 premenopausal women (mean age 41.5 -+ o.7 years) and 11 young adult premenopausal women(mean age 27.3 -+ 0.9 years) were recruited for this study. The post-peri- and pre- groups were further classified into subgroups according to their chronological age. Serum was assayed for parathyroid hormone (PTH), 25-hydroxyvitamin D, (25-OHD3), calcitonin (CT) total calcium (Ca), and inorganic phosphorus (ph), concentrations of estradiol (E2) in all subjects were also assayed for further correlation. The obtained data showed that the levels of hormones were not significantly changed among the different groups and subgroups leading to normal calcium homeostasis. PTH and total calcium were significantly correlated with both estrodial levels and chronological age

  16. The radiological impact of the Belgian phosphate industry

    International Nuclear Information System (INIS)

    The Belgian phosphate industry processes huge amounts of phosphate ore (1.5 to 2 Mton/year) for a wide range of applications, the most important being the production of phosphoric acid, fertilizers and cattle food. Marine phosphate ores show high specific activities of the natural uranium decay series (usually indicated by Ra-226) (e.g. 1200 to 1500 Bq/kg for Moroccan ore). Ores of magmatic origin generally contain less of the uranium and more of the thorium decay series (up to 500 Bq/kg). These radionuclides turn up in by-products, residues or product streams depending on the processing method and the acid used for the acidulation of the phosphate rock. Sulfuric acid is the most widely used, but also hydrochloric acid and nitric acid are applied in Belgium. For Flanders, the northern part of Belgium, we already have a clear idea of the production processes and waste streams. The five Flemish phosphate plants, from 1920 to 2000, handled 54 million ton of phosphate ore containing 65 TBq of radium-226 and 2.7 TBq of thorium- 232. The total surface area of the phosphogypsum and calcium fluoride sludge deposits amounts to almost 300 ha. There is also environmental contamination along two small rivers receiving the waste waters of the hydrochloric production process: the Winterbeek (> 200 ha) and the Grote Laak (12 ha). The data on the impact of the phosphate industry in the Walloon provinces in Belgium is less complete. A large plant produced in 2004 0.8 Mton of phosphogypsum, valorizing about 70 % of the gypsum in building materials (plaster, cement), in fertilizers, and in other products such as paper. The remainder was stored on a local disposal site. The radiological impact of the Belgian phosphate industry on the local population will be discussed. At present most contaminated areas are still recognizable as waste deposits and inaccessible to the population. However as gypsum deposits and other contaminated areas quickly blend in with the landscape, it is

  17. The role of biochemical of bone turnover markers in osteoporosis and metabolic bone disease: a consensus paper of the Belgian Bone Club.

    Science.gov (United States)

    Cavalier, E; Bergmann, P; Bruyère, O; Delanaye, P; Durnez, A; Devogelaer, J-P; Ferrari, S L; Gielen, E; Goemaere, S; Kaufman, J-M; Toukap, A Nzeusseu; Reginster, J-Y; Rousseau, A-F; Rozenberg, S; Scheen, A J; Body, J-J

    2016-07-01

    The exact role of biochemical markers of bone turnover in the management of metabolic bone diseases remains a topic of controversy. In this consensus paper, the Belgian Bone Club aimed to provide a state of the art on the use of these biomarkers in different clinical or physiological situations like in postmenopausal women, osteoporosis in men, in elderly patients, in patients suffering from bone metastasis, in patients with chronic renal failure, in pregnant or lactating women, in intensive care patients, and in diabetics. We also gave our considerations on the analytical issues linked to the use of these biomarkers, on potential new emerging biomarkers, and on the use of bone turnover biomarkers in the follow-up of patients treated with new drugs for osteoporosis. PMID:27026330

  18. Sunscreen use and skin protection behaviour on the Belgian beach: a comparison 9 years later.

    Science.gov (United States)

    Devos, Steven A; Van der Endt, Johannes D; Broeckx, Walter; Vandaele, Mark; del Marmol, Veronique; Roseeuw, Diane; Maselis, Thomas

    2012-09-01

    Public health campaigns encourage people to protect themselves against skin cancer by using sunscreens and taking other protective measures. The objective is to estimate the impact of these campaigns on the rise of awareness among the general public. This study explores the prevalence and predictors of solar protection behaviour in a sample of beachgoers and compares these results to another similar study carried out 9 years earlier (i.e. summer 2001). During the month of August 2010, a total of 408 participants (144 men and 264 women) were randomly selected on their way to the Belgian beach in the city of Ostend, Belgium. The solar protection behaviour of each participant was assessed by direct observation and an interview. The exact same questions were asked as in 2001. The general risk awareness stays the same for skin aging and skin cancer but gets higher for sunburn. When we control these results for sex, the overall higher general awareness is completely because of the higher awareness of the female subgroup. As in 2001, risk awareness is considerably higher in the female subgroup than in the male one. As in 2001, sunscreen cream was the most popular preventive behaviour in 2010 (use of sunscreen with sun protection factor 15 or higher reported by 66.4%), followed by timed sun exposure (46.8%), use of clothing and hats (36.8%) and shade (34.1%). As in summer 2001 the sunscreen use is more popular in the female population. The use of protective clothing and hats is more popular in the male group. As solar protection has become part of the beach behaviour routine, there is room for improvement for their more frequent application, the use of a higher sun protection factor (15+), timed sunbathing, more use of clothing and hats and seeking shade. The results of this study can assist in evaluating the effectiveness of present sun-protection campaigns and health education programmes. PMID:22273847

  19. Irradiation of Fuel Elements in the Belgian BR3 Reactor

    International Nuclear Information System (INIS)

    Under a contract concluded by EURATOM and CEN-BelgoNucléaire, fuel rods containing plutonium-enriched uranium were irradiated in the Belgian BR3 reactor with the object of evaluating the behaviour of plutonium fuel elements in power reactors. The first experiment consisted in introducing 12 fuel elements fabricated by vibration and compacting followed by swaging into a core assembly of the BR3 pressurized-water power reactor. Irradiation was carried out for a period corresponding to 4820 h at full power. Subsequent examination of the fuel rods showed that they had been unaffected by irradiation. A second series of experiments is being carried out in collaboration with the United Kingdom Atomic Energy Authority. These experiments involve irradiating an assembly of 37 plutonium-enriched fuel elements, some compacted and others of the pellet type, in the BR3/VN power reactor. The fabrication of the vibrocompacted elements and the thermal studies relating to the assembly are briefly described. (author)

  20. Musculoskeletal pain among women of menopausal age in Puebla, Mexico.

    Science.gov (United States)

    Sievert, Lynnette Leidy; Goode-Null, Susan K

    2005-06-01

    Worldwide, complaints of musculoskeletal pain are more frequent than complaints of hot flashes amongst women of menopausal age. The purpose of this study was to examine musculoskeletal pain among women of menopausal age in the city of Puebla, Mexico. An opportunity sample was recruited from public parks and markets, with representation from all social classes (n=755). Mean age was 50.1 years, and the majority were employed as saleswomen in small businesses. Symptom frequencies were collected by open-ended interviews and with a structured symptom list that queried symptom experience during the two weeks prior to interview. In response to open-ended questions, "dolores de huesos" (bone pain) was volunteered by 47% of respondents as a symptom associated with menopause, second only to hot flashes (53%). From the structured symptom list, 55.8% and 55.6% reported back pain and joint stiffness during the two weeks prior to interview. Women with back pain and joint stiffness were less likely to report being active during their leisure time (p<.01). The results of backwards stepwise logistic regressions indicate that women with back pain were more likely to be older, with less education, a higher BMI, and ate less meat. Women with joint pain were more likely to be post-menopausal, with less education, more children, a higher BMI, and were likely to drink milk and coffee more than once/week but less than once/day. While menopause is not necessarily a risk factor for musculoskeletal pain, it is important to recognize the pervasiveness of this complaint among women of menopausal age. PMID:16917748

  1. Retrobulbar hemodynamic parameters in men and women with open angle glaucoma

    Directory of Open Access Journals (Sweden)

    Marjanović Ivan

    2014-01-01

    Full Text Available Background/Aim. Several factors may have influence on systemic circulation. Additionally, peripheral circulation also demonstrates sex differences, in young women presenting significantly lower finger blood flow in comparison to men of the same age, a finding that disappears in women after menopause. The aim of this study was to compare the retrobulbar hemodynamic parameters measured by means of color Doppler imaging in women and men with open-angle glaucoma and elevated intraocular pressure. Methods. A total of 52 eyes from 52 open-angle glaucoma (OAG patients, with elevated intraocular pressure (IOP, were included in this cross-sectional study. Peak-systolic velocity (PSV, end-diastolic velocity (EDV, and Pourcelot resistivity index (RI were assessed in the ophtalmic artery (OA, central retinal artery (CRA, and posterior cilliary arteries (PCA. IOP was measured both with Goldmann Applanation tonometer (GAT and with the dynamic contour tonometer (DCT, three times respectively. Ocular pulse amplitude (OPA appeared during the DCT measurement. Results. The retrobulbar hemodynamic parameters did not show any difference between men and post-menopausal women. Conclusion. The results of our study did not find any difference between sexes in patients with open-angle glaucoma and elevated intraocular pressure.

  2. Estudo exploratório da associação entre o perfil lipídico e a densidade mineral óssea em mulheres menopausadas, em hospital de referência de Campinas Association between lipid profile and bone mineral density in post-menopausal women

    OpenAIRE

    Silval Fernando Cardoso Zabaglia; Adriana Orcesi Pedro; Aarão Mendes Pinto Neto; Telma Guarisi; Lucia Helena Simões da Costa Paiva; Eduardo Lane

    1998-01-01

    O objetivo deste estudo foi avaliar a possível associação entre algumas variáveis do perfil lipídico e a densidade mineral óssea e se estas variáveis poderiam ser usadas como indicadoras de massa óssea em mulheres menopausadas, atendidas no ambulatório de menopausa do CAISM-Unicamp, no ano de 1995. Estudaram-se 72 pacientes pós-menopausadas, sem fatores de risco para doenças cardiovasculares e para osteoporose, por meio da dosagem de colesterol total e frações e da avaliação da densidade mine...

  3. The Belgian nuclear education network, 5th academic year

    International Nuclear Information System (INIS)

    Full text: In a country where a substantial part of the electricity generation will remain of nuclear origin for a number of years, there is a need for well educated and well trained engineers in this area. Public authorities, regulators and industry brought their support to this initiative. In 2001, the Belgian Nuclear Research Centre SCK CEN and five Belgian universities signed a consortium agreement to set up an education programme in nuclear engineering. This academic year, a sixth university, ULB, joined the programme. The universities involved are now: KUL (Leuven), UG (Ghent), VUB (Brussels), UCL (Louvain-la-Neuve), ULg (Liege) and ULB (Brussels). These seven partners have engaged themselves anew to provide students and young-professionals with a high-standard nuclear engineering programme. The BNEN academic programme is a one-year (60 ECTS) Master-after-Master programme open for holders of a Master degree in engineering. The programme consists of ten courses to be followed mandatory (41 ECTS), the opportunity to select a number of advanced courses at will (up to 4 ECTS worth) and a Master thesis (15 ECTS). The subjects of the courses range form nuclear physics, nuclear reactor theory, nuclear thermo hydraulics to reactor plant operation and control, radiation protection and safeguards and nuclear materials. It also includes courses on nuclear energy and the nuclear fuel cycle. All courses are given in a modular fashion, i.e. the students get a course in the duration of one up to three weeks of continuous lectures and lab sessions. Attention is indeed paid to the fact that most courses are not only theoretical ones, but many of them have exercise sessions and laboratory sessions associated with them. These sessions are organised and thought by the scientific staff at SCK CEN. The number of students enrolling for the BNEN has seen a serious growth since the start of the initiative. The programme does not serve only 'full-time' students, i.e. people having

  4. The Belgian laboratory for standard dosimetry calibrations used in radiotherapy

    International Nuclear Information System (INIS)

    Starting from the end of the year 2008, the RDC (Radiation Protection dosimetry and Calibrations) expertise group of SCK CEN took over the calibration and research activities at the Laboratory for Standard Dosimetry Ghent. The laboratory runs under a collaboration between SCK CEN and the University of Ghent, with the support of Federal Agency for Nuclear Control (FANC). The calibrations in Ghent were stopped at the beginning of 2008 and then restarted at the end of 2008. A new 60Co source was installed at Ghent, a Theratron 780 unit. All the calibration setups installed in the past to the old 60Co source had to move to the new source and measurement history had to be acquired. The calibration of cylindrical and plane-parallel ionization chambers in terms of absorbed dose to water was defined as the first priority, since there was an urgent need from the Belgian hospitals. These calibrations are presently done in Ghent as secondary standard calibrations, traceable to the water calorimeter of VSL, Delft, The Netherlands and following the recommendations from TRS-398 protocol. The second priority was restarting the calibrations of cylindrical ionization chambers in terms of air kerma. A cylindrical graphite ionization chamber of type CC01 is used for the absolute measurement of air kerma. Both setups are fully operational. Special efforts were done to implement the SCK CEN quality assurance (QA) system regarding ISO 17025 accreditation. The activity at the laboratory in Ghent was integrated as part of the Laboratory for Nuclear Calibrations (LNK-from the Dutch translation) of the SCK-CEN. Most of the activities of the LNK are already accredited by Belgian Accreditation Body (BELAC) with respect to the ISO-17025 standards. The quality assurance procedures were prepared and are routinely followed for the two new setups mentioned above: calibrations in terms of absorbed dose to water and air kerma in 60Co beam. During the preparation of the quality assurance procedures

  5. Pedometer-Determined Physical Activity and Its Comparison with the International Physical Activity Questionnaire in a Sample of Belgian Adults

    Science.gov (United States)

    De Cocker, Katrien; Cardon, Greet; De Bourdeaudhuij, Ilse

    2007-01-01

    Pedometer-determined physical activity (PA) levels in Belgian adults were provided and compared to PA scores reported in the International Physical Activity Questionnaire (IPAQ). The representative sample (N = 1,239) of the Belgian population took on average 9,655 (4,526) steps/day. According to pedometer indices 58.4% were insufficiently active.…

  6. High Prevalence of Vitamin D Deficiency in Pregnant Women: A National Cross-Sectional Survey

    OpenAIRE

    Vandevijvere, Stefanie; Amsalkhir, Sihame; Van Oyen, Herman; Moreno-Reyes, Rodrigo

    2012-01-01

    An increasing number of studies suggest that vitamin D deficiency during pregnancy is associated with multiple adverse health outcomes in mothers, neonates and children. There are no representative country data available on vitamin D status of pregnant women in Europe. The aim of this study was to estimate the prevalence of vitamin D deficiency among Belgian pregnant women and to assess the determinants of vitamin D status in the first and third trimester of pregnancy. The women were selected...

  7. A survey of bacteria found in Belgian dairy farm products

    Directory of Open Access Journals (Sweden)

    N'Guessan, E.

    2015-01-01

    Full Text Available Description of the subject. Due to the potential hazards caused by pathogenic bacteria, farm dairy production remains a challenge from the point of view of food safety. As part of a public program to support farm diversification and short food supply chains, farm dairy product samples including yogurt, ice cream, raw-milk butter and cheese samples were collected from 318 Walloon farm producers between 2006 and 2014. Objectives. Investigation of the microbiological quality of the Belgian dairy products using the guidelines provided by the European food safety standards. Method. The samples were collected within the framework of the self-checking regulation. In accordance with the European Regulation EC 2073/2005, microbiological analyses were performed to detect and count Enterobacteriaceae, Listeria monocytogenes, Salmonella spp., Escherichia coli and Staphylococcus aureus. Results. Even when results met the microbiological safety standards, hygienic indicator microorganisms like E. coli and S. aureus exceeded the defined limits in 35% and 4% of butter and cheese samples, respectively. Unsatisfactory levels observed for soft cheeses remained higher (10% and 2% for S. aureus and L. monocytogenes respectively than those observed for pressed cheeses (3% and 1% and fresh cheeses (3% and 0% (P ≥ 0.05. Furthermore, the percentages of samples outside legal limits were not significantly higher in the summer months than in winter months for all mentioned bacteria. Conclusions. This survey showed that most farm dairy products investigated were microbiologically safe. However, high levels of hygiene indicators (e.g., E. coli in some products, like butter, remind us of applying good hygienic practices at every stage of the dairy production process to ensure consumer safety.

  8. Compliance of Companies with Corporate Governance Codes: Case Study on Listed Belgian

    Directory of Open Access Journals (Sweden)

    Sven H. De Cleyn

    2014-09-01

    Full Text Available Listed and large companies become increasingly subject to internal and external pressure to comply with ethical and social standards. This article focuses on one aspect of this matter, namely the corporate governance issue. Within the framework of recent corporate scandals, this paper investigates whether and to which extent Belgian publicly listed SMEs comply with the Belgian Code on Corporate Governance after its first year of introduction, which has been constituted in the framework of the European Action Plan on Corporate Governance.In a sample of 78 Belgian listed SMEs, the compliance with the Code is analysed. After its first year of introduction, companies comply with on average 70% of the Code’s provisions. The most problematic topics in terms of disclosure of information seem to relate to (individual remuneration, private information and content of shareholders’ meetings.

  9. Belgian nuclear forum - launching the public debate on nuclear energy

    International Nuclear Information System (INIS)

    In the past decades, public opinion on nuclear power was dominated by a 'sleeping', indifferent majority. Nothing moved until (a minority of) opponents began to stir. Their activism strongly contrasted with the low-profile attitude of the nuclear players and pushed a considerable part of the indifferent majority towards a more negative attitude. A 2007 opinion poll (IFOP) confirmed this trend. The poll also revealed a major lack of objective and factual information. Incorrect and incomplete arguments tended to demonize nuclear energy, and 'nuclear' became a brand polarizing public opinion. This had a negative impact on decision-makers and culminated in the Belgian phase-out law of 2003. Based on the opinion poll, the members of the Belgian Nuclear Forum decided to launch a public information campaign, which they would jointly finance, with these goals: - In 3 to 4 years time, create greater public awareness on energy matters and move public opinion towards a more positive attitude. - Gain recognition of nuclear energy's legitimate place in the mix, and of the importance of peaceful nuclear applications. - Attract attention to the Belgian know-how and the importance of the industry on the scientific and economical level. - Optimize conditions for important nuclear issues such as long-term operation of NPPs, new nuclear research projects (MYRRHA),.. A 'push-pull' approach was adopted: push communication to the public (campaign) to pull (involve) decision-makers and get nuclear back on the political agenda. The Forum also opted for a sustained, long-term effort based on public campaigning, public relations and public affairs. Considering its long-time absence from the public debate, the Forum and its agency Saatchi and Saatchi agreed upon the following principles to underpin the campaign: - No 'pro-campaign'; that would be highly unrealistic and have a negative effect; - No taboos: bring up both the pros and cons; - No emotions: bring reason into a mainly emotional

  10. Belgian nuclear forum - launching the public debate on nuclear energy

    Energy Technology Data Exchange (ETDEWEB)

    Leclere, Robert [Belgian Nuclear Forum, Gulledelle, 1200 Brussels (Belgium); Van Landeghem, Yves [Saatchi and Saatchi Belgium, Avenue Rogier, 1030 Brussels (Belgium)

    2010-07-01

    In the past decades, public opinion on nuclear power was dominated by a 'sleeping', indifferent majority. Nothing moved until (a minority of) opponents began to stir. Their activism strongly contrasted with the low-profile attitude of the nuclear players and pushed a considerable part of the indifferent majority towards a more negative attitude. A 2007 opinion poll (IFOP) confirmed this trend. The poll also revealed a major lack of objective and factual information. Incorrect and incomplete arguments tended to demonize nuclear energy, and 'nuclear' became a brand polarizing public opinion. This had a negative impact on decision-makers and culminated in the Belgian phase-out law of 2003. Based on the opinion poll, the members of the Belgian Nuclear Forum decided to launch a public information campaign, which they would jointly finance, with these goals: - In 3 to 4 years time, create greater public awareness on energy matters and move public opinion towards a more positive attitude. - Gain recognition of nuclear energy's legitimate place in the mix, and of the importance of peaceful nuclear applications. - Attract attention to the Belgian know-how and the importance of the industry on the scientific and economical level. - Optimize conditions for important nuclear issues such as long-term operation of NPPs, new nuclear research projects (MYRRHA),.. A 'push-pull' approach was adopted: push communication to the public (campaign) to pull (involve) decision-makers and get nuclear back on the political agenda. The Forum also opted for a sustained, long-term effort based on public campaigning, public relations and public affairs. Considering its long-time absence from the public debate, the Forum and its agency Saatchi and Saatchi agreed upon the following principles to underpin the campaign: - No 'pro-campaign'; that would be highly unrealistic and have a negative effect; - No taboos: bring up both the pros and cons; - No

  11. Legacy of Colonialism in the Empowerment of Women in Rwanda

    Directory of Open Access Journals (Sweden)

    Ilaria Buscaglia

    2012-03-01

    Full Text Available The empowerment of women in Rwanda is rooted in colonial times. In the second half of the 1940s, the Belgian administration, together with religious missionaries, started some educational and social welfare programs for women, known as the foyers sociaux (social homes. This paper explores how this program of female promotion and its progeny affected the domestication of Rwandan women, what caused the situation to change following the genocide against the Tutsi in 1994, and what more might be done to stimulate full gender equality in education and employment for women in Rwanda.

  12. Differences in body parameters of Pre- and Postmenopausal women and possible association with factors of cardiovascular diseases

    Directory of Open Access Journals (Sweden)

    K. Kaur

    2014-12-01

    Full Text Available Background: Body composition changes become evident in women as they pass through the transition phase of their life where their reproductive phase ends up at menopause. Women at menopause often experience redistribution of body fat particularly around the abdomen. Redistribution of body fat among postmenopausal women leads to various metabolic syndromes which lead to cardiovascular diseases even with controlled BMI. Material and Method: For the present cross-sectional study, 530 women (300 pre- and 230 postmenopausal ranging in age from 30-60 years were personally interviewed and their anthropometric and physiological parameters were measured with standardized methods. Their height, weight, waist circumference, biceps, triceps, sub scapular and suprailiac measurements were taken and blood pressure was noted down. From these values, their waist-hip ratio, waist-stature ratio, percent body fat, total body fat, pulse pressure, mean arterial pressure were calculated. Pearson’s correlation was computed to find out the association of BP with various anthropometric parameters. Results and Conclusion: Positive association of waist circumference, waist hip ratio, percent body fat and total body fat was observed with systolic and diastolic blood pressure. Present observations support the notion that hormonally-induced redistribution of adipose tissue at menopause in the intra-abdominal depots in post-menopausal women might be leading to adverse changes in the metabolic profile.

  13. Non-destructive method for internal quality determination of belgian endive (cichorium intybus l.)

    OpenAIRE

    De Baerdemaeker J.; Quenon V.

    2000-01-01

    A method and process were developed to nondestructively measure the length of the floral stalk in Belgian endive Cichorium intybus L. Current X-ray technology proved to be a feasible method. A detection algorithm was developed based on the minimal transmitted intensities along the length. The method is very accurate with an absolute precision of 4.9 mm and allows the study of the influence of storage conditions and time on the Belgian endive internal quality. The growth of the floral stalk is...

  14. Core and fuel feasibility study for improved flexibility on the Belgian Nuclear Power Plants

    International Nuclear Information System (INIS)

    A feasibility study has been performed for extended power modulations on Belgian NPPs. The goal is to make the existing nuclear power units in Belgium more flexible without implementing hardware modifications and guaranteeing safety at all times. As the critical part of the feasibility study, the impacts on the core behaviour and fuel performance have been studied in detail. It is concluded that all existing fuels loaded in the Belgian plants allow up to 30 power modulations per fuel cycle without changing the currently applied fuel cycle management. This is also supported by the extensive experience feedback of the fuel products for flexible operations in European countries. (author)

  15. Sand dynamics along the Belgian coast based on airborne hyperspectral data and lidar data

    OpenAIRE

    Deronde, B; Houthuys, R.; Sterckx, S.; Fransaer, D.

    2005-01-01

    The goal of this project was to explore the possibilities of airborne hyperspectral data and airborne lidar data to study sand dynamics on the Belgian backshore and foreshore. The Belgian coast is formed by a sandy strip at the southern edge of the North Sea Basin which is commonly known as the Southern Bight. Since the beach is prone to structural and occasional erosion, it is very important to obtain a better understanding of the processes controlling it. The combination of multi-temporal h...

  16. A faunistic survey of the Belgian marine molluscs: a first progress report

    OpenAIRE

    Backeljau, T.

    1988-01-01

    A first step towards the compilation of a critical faunistic inventory of the Belgian marine mollusks, was the publication of a preliminary nomenclatural list in 1986. This list mentioned 136 species which until then bad been recorded alive in Belgium. Yet, such records do not necessarily mean that the species involved actually belong to our fauna. Hence, the next thing to do, was to start a more profound survey of the Belgian marine malacofauna in order to determine which species form well-e...

  17. Intraocular pressure in postmenopausal Nigerian women with and without systemic hypertension

    Directory of Open Access Journals (Sweden)

    J. A. Ebeigbe

    2011-12-01

    Full Text Available Background: Mean intraocular pressure (IOP in postmenopausal women has been reported higher than that in menstruating women. Also, intraocular pressure is said to be positively correlated with systemic blood pressure. No previous study in Nigeria has compared intraocular pressure in postmenopausal women with and without systemic hypertension. Purpose: To investigate the effects of menopause on intraocular pressure in subjects with and without high blood pressure. Methods: Normotensive and hypertensive premenopausal and postmenopausal subjects in the   same agerange of 45 to 55 years were studied. Intraocular pressure was measured with the hand-held Kowa applanation tonometer.  Blood pressure was taken in the sitting position at the right upper arm using a manual mercury sphygmomanometer with the right cuff size. The average of two readings was recorded. Results: Mean IOP for premenopausal normotensive women was 14.58 ± 2.56 mmHg whilethat of postmenopausal normotensive women was16.15 ± 1.80 mmHg (p<0.05.  Also, the difference in mean IOP between premenopausal hypertensive (16.58 ± 3.23 mmHg and postmenopausal hypertensive women (18.24 ± 3.89 mmHgwas statistically significant (p<0.05. A statistically significant and positive correlation was observed between IOP and systemic blood pressure in postmenopausal hypertensive women, p<0.05.Conclusion: Menopause significantly increases intraocular pressure. Mean intraocular pressure of hypertensive postmenopausal women was significantly higher than that of normotensive post-menopausal women, (p<0.05. Knowledge of the normal level of intraocular pressure during various stages of the female reproductive cycle may help during glaucoma screening. (S Afr Optom 2011 70(3 117-122

  18. Attitude of a group of Belgian stakeholders towards proposed agricultural countermeasures after a radioactive contamination: synthesis of the discussions within the Belgian EC-FARMING group

    International Nuclear Information System (INIS)

    In the case of radioactive contamination of the environment with an impact on the food chain, the remediation strategy will not only be based on scientific knowledge and technical experience, but will also be dictated by peculiarities of the country. These characteristics include the agro-industrial structure, the local and international economical contexts and the political configuration including the distribution of responsibilities and competencies. This paper identifies and illustrates the most relevant characteristics of the Belgian agricultural system and political environment; it also describes the past experience with food chain contamination, which is expected to influence the attitude of Belgian stakeholders, who would be involved in the setting up of countermeasure strategies for maintaining agricultural production and food safety. The picture drawn explains why several countermeasures aiming to reduce the contamination in food products, although scientifically sound and technically feasible, are hardly acceptable or even not acceptable at all, to the stakeholders

  19. Are patterns of bone loss in anorexic and postmenopausal women similar? Preliminary results using high resolution peripheral computed tomography.

    Science.gov (United States)

    Milos, Gabriella; Häuselmann, Hans-Jörg; Krieg, Marc-Antoine; Rüegsegger, Peter; Gallo, Luigi M

    2014-01-01

    This study intended to compare bone density and architecture in three groups of women: young women with anorexia nervosa (AN), an age-matched control group of young women, and healthy late postmenopausal women. Three-dimensional peripheral quantitative high resolution computed-tomography (HR-pQCT) at the ultradistal radius, a technology providing measures of cortical and trabecular bone density and microarchitecture, was performed in the three cohorts. Thirty-six women with AN aged 18-30 years (mean duration of AN: 5.8 years), 83 healthy late postmenopausal women aged 70-81 as well as 30 age-matched healthy young women were assessed. The overall cortical and trabecular bone density (D100), the absolute thickness of the cortical bone (CTh), and the absolute number of trabecules per area (TbN) were significantly lower in AN patients compared with healthy young women. The absolute number of trabecules per area (TbN) in AN and postmenopausal women was similar, but significantly lower than in healthy young women. The comparison between AN patients and post-menopausal women is of interest because the latter reach bone peak mass around the middle of the fertile age span whereas the former usually lose bone before reaching optimal bone density and structure. This study shows that bone mineral density and bone compacta thickness in AN are lower than those in controls but still higher than those in postmenopause. Bone compacta density in AN is similar as in controls. However, bone inner structure in AN is degraded to a similar extent as in postmenopause. This last finding is particularly troubling. PMID:24084384

  20. Can metacognition compensate for intelligence in the first year of Belgian higher education?

    NARCIS (Netherlands)

    Minnaert, A

    1996-01-01

    This study reports on the effects of metacognitive knowledge and skills compensating for intelligence in relation to academic performance in the first year of Belgian higher education. About 600 freshmen of educational sciences, medicine and psychology participated in this project. Tasks and questio

  1. Comparing Compositional Effects in Two Education Systems: The Case of the Belgian Communities

    Science.gov (United States)

    Danhier, Julien; Martin, Émilie

    2014-01-01

    The Belgian educational field includes separate educational systems reflecting the division of the country into linguistic communities. Even if the French-speaking and the Dutch-speaking communities keep sharing important similarities in terms of funding rules and structures, they present a huge gap between their respective pupils'…

  2. Performance Measurement in Belgian Hospitals : a state-of-the-art

    OpenAIRE

    Van Caillie, Didier; Rouhana, Rima; Santin, Sarah

    2007-01-01

    This communication proposes a global state-of-the-art around the central question : "How is performance measured and controlled in Belgian hospitals. As a first step in a global research project dedicated to the use of Balanced ScoreCard in publics hospitals around the world, it is essentially focused on global economic aspects and on major macroeconomic statistics.

  3. Clonal Expansion of the Belgian Phytophthora ramorum Populations Based on New Microsatellite Markers

    Science.gov (United States)

    Coexistence of both mating types A1 and A2 within the EU1 lineage of Phytophthora ramorum has only been observed in Belgium, begging the question whether sexual reproduction is occurring. A collection of 411 Belgian P. ramorum isolates was established during a seven year survey. Our main objective w...

  4. Osteochondrosis of the occipital condyles and atlanto-occipital dysplasia in a Belgian horse

    OpenAIRE

    Muirhead, Tammy; McClure, J.T.; Bourque, Andrea; Pack, LeeAnn

    2003-01-01

    A lesion in the cervical region of a 14-month-old Belgian gelding with severe ataxia was suspected. Necropsy revealed symmetric focal cartilage defects compatible with osteochondrosis of the occipital condyles and atlanto-occipital dysplasia. To our knowledge this is the first equine report of symmetrical osteochondrosis of the occipital condyles causing neurologic signs.

  5. The role of the sickness funds in the Belgian health care market

    NARCIS (Netherlands)

    W. Nonneman (Nonneman); E.K.A. van Doorslaer (Eddy)

    1994-01-01

    textabstractThis article reviews some of the salient features of the Belgian health care finance and delivery system. Special attention is paid to the role played by the third-party payers, i.e. the Health Insurance Associations (HIAs) in administering the compulsory national health insurance progra

  6. Chikungunya infection confirmed in a Belgian traveller returning from Phuket (Thailand)

    OpenAIRE

    Bottieau, E; Van Esbroeck, M.; Cnops, L.; Clerinx, J; van Gompel, A.

    2009-01-01

    Chikungunya infection has been increasingly reported in international travellers following its epidemic re-emergence in the Indian Ocean islands in 2006 and its spread to southern Asia thereafter. We describe the first case of chikungunya in a Belgian traveller returning from Phuket, Thailand and discuss the potential implications of chikungunya cases imported to European countries for patient management and public health.

  7. Speaking Turkish in Belgian primary schools: teacher beliefs versus effective consequences

    NARCIS (Netherlands)

    O. Ağırdağ; K. Jordens; M. Van Houtte

    2014-01-01

    In this mixed-method study, we explore teachers’ beliefs concerning the use of the Turkish language by Turkish children in Belgian primary schools, and we compare these findings with the effective consequences of language maintenance. The qualitative analyses revealed that teachers have very negativ

  8. Mechanical testing and microstructural characterization of pressure vessel at decommissioned Belgian BR3 Plant

    International Nuclear Information System (INIS)

    The objective of this paper was a discussion of a proposal to perform mechanical testing and microstructural characterization of the annealed reactor vessel of the Belgian BR-3 reactor. Motivation for this effort was discussed, and a preliminary cost estimate for some of the tasks was also presented

  9. Breast cancer in Mexican women: an epidemiological study with cervical cancer control

    Directory of Open Access Journals (Sweden)

    Víctor Tovar-Guzmán

    2000-04-01

    Full Text Available INTRODUCTION: In Mexico, breast cancer (BC is one of the main causes of cancer deaths in women, with increasing incidence and mortality in recent years. Therefore, the aim of the study is identify possible risk factors related to BC. METHODS: An epidemiological study of hospital cases of BC and controls with cervical uterine cancer (CUCA was carried out at eight third level concentration hospitals in Mexico City. The total of 353 incident cases of BC and 630 controls with CUCA were identified among women younger than 75 years who had been residents of the metropolitan area of Mexico City for at least one year. Diagnosis was confirmed histologically in both groups. Variables were analyzed according to biological and statistical plausibility criteria. Univariate, bivariate and multivariate analyses were carried out. Cases and controls were stratified according to the menopausal hormonal status (pre and post menopause. RESULTS: The factors associated with BC were: higher socioeconomic level (OR= 2.77; 95%CI = 1.77 - 4.35; early menarche (OR= 1.32; 95%CI= 0.88 - 2.00; old age at first pregnancy (>31 years: OR= 5.49; 95%CI= 2.16 - 13.98 and a family history of BC (OR= 4.76; 95% CI= 2.10 - 10.79. In contrast, an increase in the duration of the breastfeeding period was a protective factor (>25 months: OR= 0.38; 95%CI= 0.20 - 0.70. CONCLUSIONS: This study contributes to the identification of risk factors for BC described in the international literature, in the population of Mexican women. Breastfeeding appears to play an important role in protecting women from BC. Because of changes in women`s lifestyles, lactation is decreasing in Mexico, and young women tend not to breastfeed or to shorten the duration of lactation.

  10. Breast cancer in Mexican women: an epidemiological study with cervical cancer control

    Directory of Open Access Journals (Sweden)

    Tovar-Guzmán Víctor

    2000-01-01

    Full Text Available INTRODUCTION: In Mexico, breast cancer (BC is one of the main causes of cancer deaths in women, with increasing incidence and mortality in recent years. Therefore, the aim of the study is identify possible risk factors related to BC. METHODS: An epidemiological study of hospital cases of BC and controls with cervical uterine cancer (CUCA was carried out at eight third level concentration hospitals in Mexico City. The total of 353 incident cases of BC and 630 controls with CUCA were identified among women younger than 75 years who had been residents of the metropolitan area of Mexico City for at least one year. Diagnosis was confirmed histologically in both groups. Variables were analyzed according to biological and statistical plausibility criteria. Univariate, bivariate and multivariate analyses were carried out. Cases and controls were stratified according to the menopausal hormonal status (pre and post menopause. RESULTS: The factors associated with BC were: higher socioeconomic level (OR= 2.77; 95%CI = 1.77 - 4.35; early menarche (OR= 1.32; 95%CI= 0.88 - 2.00; old age at first pregnancy (>31 years: OR= 5.49; 95%CI= 2.16 - 13.98 and a family history of BC (OR= 4.76; 95% CI= 2.10 - 10.79. In contrast, an increase in the duration of the breastfeeding period was a protective factor (>25 months: OR= 0.38; 95%CI= 0.20 - 0.70. CONCLUSIONS: This study contributes to the identification of risk factors for BC described in the international literature, in the population of Mexican women. Breastfeeding appears to play an important role in protecting women from BC. Because of changes in women`s lifestyles, lactation is decreasing in Mexico, and young women tend not to breastfeed or to shorten the duration of lactation.

  11. Pesticide exposure of two age groups of women and its relationship with their diet.

    Science.gov (United States)

    Rivas, Ana; Cerrillo, Isabel; Granada, Alicia; Mariscal-Arcas, Miguel; Olea-Serrano, Fatima

    2007-08-15

    The widespread presence of organochlorine (OC) pesticides in human samples may be explained by the environmental exposure of the population. Foods are considered a constant source of exposure, despite compliance with maximum permitted residue levels. This study aimed to examine the relationship between nutritional habits of women in Southeast Spain and their serum concentrations of OCs. A semi-quantitative questionnaire was used to estimate the frequency of consumption of foods by two age groups of women, pre-menopausal (Pre-M) and post-menopausal (Post-M), and their serum pesticide levels were measured by gas chromatography (GC) with electron capture detector and confirmed by GC and mass spectrometry. The Pre-M group showed significantly higher serum concentrations of all OCs studied with the exception of DDE. The groups significantly differed in consumption of all food groups with the exception of fruit. In the Pre-M group, the mean serum p,p-DDT concentration was significantly associated with milk/yoghurt (presidue levels to minimize this threat to human and animal health. PMID:17477954

  12. Suspended Particulate Matter (SPM) mapping from MERIS imagery. Calibration of a regional algorithm for the Belgian coastal waters

    OpenAIRE

    B. Nechad; De Cauwer, V.; PARK, Y.; Ruddick, K. G.

    2003-01-01

    A hydro-optical algorithm based on reflectance at 555nm has been used in the past for suspended particulate matter concentrations (SPM) retrieval from SeaWiFS over the Belgian coastal (case II) waters in Southern North Sea. The extra spectral resolution of MERIS offers the possibility of improvements, though necessitates algorithm recalibration. This study presents the calibration of the hydro-optical model used to derive SPM from MERIS reflectance for Belgian coastal waters. The model is bas...

  13. Adapting to the system or the student? Exploring teacher adaptations to disadvantaged students in an English and Belgian secondary school

    OpenAIRE

    Stevens, Peter; Van Houtte , Mieke

    2011-01-01

    This article builds on research on teacher adaptations to students by exploring how a Belgian and English national context influence teachers’ definitions of educational success, their explanations of educational failure and allocation of scarce educational resources to disadvantaged students. Ethnographic data from one Flemish (Belgian) and one English secondary, multicultural school suggest that teachers in both schools adapt their expectations to students in line with the perceived ability...

  14. Why do women stop reproducing before menopause? A life-history approach to age at last birth.

    Science.gov (United States)

    Towner, Mary C; Nenko, Ilona; Walton, Savannah E

    2016-04-19

    Evolutionary biologists have long considered menopause to be a fundamental puzzle in understanding human fertility behaviour, as post-menopausal women are no longer physiologically capable of direct reproduction. Menopause typically occurs between 45 and 55 years of age, but across cultures and history, women often stop reproducing many years before menopause. Unlike age at first reproduction or even birth spacing, a woman nearing the end of her reproductive cycle is able to reflect upon the offspring she already has-their numbers and phenotypic qualities, including sexes. This paper reviews demographic data on age at last birth both across and within societies, and also presents a case study of age at last birth in rural Bangladeshi women. In this Bangladeshi sample, age at last birth preceded age at menopause by an average of 11 years, with marked variation around that mean, even during a period of high fertility. Moreover, age at last birth was not strongly related to age at menopause. Our literature review and case study provide evidence that stopping behaviour needs to be more closely examined as an important part of human reproductive strategies and life-history theory. Menopause may be a final marker of permanent reproductive cessation, but it is only one piece of the evolutionary puzzle. PMID:27022074

  15. The Belgian experience on the backfitting and safety upgrading of old operating nuclear power plants

    International Nuclear Information System (INIS)

    The paper describes the methodology for backfitting and safety upgrading during the reevaluation of the Belgian NPP's: first generation (Doel-1, Doel-2, Tihange-1) and second generation plants (Doel-3, Doel-4, Tihange-2 and Tihange-3). A list of essential safety subjects and topics is given. The experience has proved the feasibility of a safety upgrading of operating NPP without injury to its availability, the benefit of a close cooperation between owner, engineering company and safety authorities throughout the project. A global approach to solving numerous specific deficiencies along with the optimization of the investments regarding the safety improvement of the NPP is suggested. Further increase of the know-how will be achieved through the present Belgian programme along with similar activities abroad. (R.I.)

  16. SAFIR-2 and the Belgian methodological R and D programme on deep disposal

    International Nuclear Information System (INIS)

    Peter de Preter (NIRAS/ONDRAF, Belgium) provided an overview of the Belgian programme of research and development on deep disposal. The planned submission in December 2001 of SAFIR 2 (the second Safety Assessment and Feasibility Interim Report) would mark an important milestone, as the report would inform a decision by the Belgian government on the nature of future research. An independent committee of scientists established by NIRAS/ONDRAF had reviewed a draft version of the report. The committee was generally in agreement with the technical R and D priorities proposed in the report but suggested that there should be more integration of technical and societal aspects. The committee also recommended that a future research programme should compare the option of deep disposal with other strategies for long-term management of radioactive wastes. It was suggested that a strategic environmental assessment might provide an appropriate mechanism for comparing alternative management strategies, and would enable societal dimensions also to be addressed

  17. Sensitivity analyses of thermal bridges: confrontation with the new Belgian EPB-methodology

    OpenAIRE

    Delghust, Marc; Huyghe, Willem; Janssens, Arnold

    2011-01-01

    As governments continue to impose more and higher energetic requirements for buildings, they also need better assessment-tools to take into account as many parameters as possible. This results in continuous developments of new calculation methods and softwares, where a balance has to be found between practicality and accuracy. To answer this problem, specifically with regard to the thermal bridges, the three Belgian regions developed a new and common pragmatic approach for assessing therma...

  18. The Gay Men Sex Studies: prevalence of sexual dysfunctions in Belgian HIV+ gay men

    OpenAIRE

    Vansintejan J; Janssen J; Van De Vijver E; Vandevoorde J; Devroey D

    2013-01-01

    Johan Vansintejan, Joris Janssen, Erwin Van De Vijver, Jan Vandevoorde, Dirk Devroey Department of Family Medicine, Vrije Universiteit Brussel (VUB), Brussels, Belgium Abstract: The aim of this Internet-based survey was to investigate the prevalence and associated predictors of sexual dysfunctions in Belgian self-reported HIV-positive men who have sex with other men. Of the 72 participants, 56% had a mild-to-severe erectile dysfunction, and 15% reported a hypoactive sexual desire disorder. Th...

  19. The Gay Men Sex Studies: prevalence of sexual dysfunctions in Belgian HIV+ gay men

    OpenAIRE

    Vansintejan, Johan

    2013-01-01

    Johan Vansintejan, Joris Janssen, Erwin Van De Vijver, Jan Vandevoorde, Dirk Devroey Department of Family Medicine, Vrije Universiteit Brussel (VUB), Brussels, Belgium Abstract: The aim of this Internet-based survey was to investigate the prevalence and associated predictors of sexual dysfunctions in Belgian self-reported HIV-positive men who have sex with other men. Of the 72 participants, 56% had a mild-to-severe erectile dysfunction, and 15% reported a hypoactive sexual desire disorder. T...

  20. Average daily nitrate and nitrite intake in the Belgian population older than 15 years

    OpenAIRE

    Temme, Liesbeth; Vandevijvere, Stefanie Marie; Vinkx, Christine; Huybrechts, Inge; Goeyens, Leo; Van Oyen, Herman

    2011-01-01

    Abstract The aim of this study was to assess the dietary intake of nitrate and nitrite in Belgium. The nitrate content of processed vegetables, cheeses and meat products was analyzed. These data were completed by data from non-targeted official control and from literature. In addition, the nitrite content of meat products was measured. Concentration data for nitrate and nitrite were linked to food consumption data of the Belgian Food Consumption Survey. This study included 3245 res...

  1. Estimating an Ex Ante Cost Function for Belgian Arable Crop Farms

    OpenAIRE

    Hansen, Kristiana; Baudry, Alexandre; De Blander, Rembert; Frahan, Bruno Henry de; Polome, Philippe

    2009-01-01

    We estimate a farm-level cost function for Belgian crop farms using FADN data over the study period 1996-2006. We rely on an estimation of farmers' expected yields at the time cropping decisions are made rather than actual yields observed in the FADN data. The use of an ex ante cost function improves the cost function estimation. We subsequently suggest how our cost function can be used in simulations to analyze farmer response to changes in output price risk.

  2. Waste disposal[1997 Scientific Report of the Belgian Nuclear Research Centre

    Energy Technology Data Exchange (ETDEWEB)

    Neerdael, B.; Marivoet, J.; Put, M.; Verstricht, J.; Van Iseghem, P.; Buyens, M.

    1998-07-01

    The primary mission of the Waste Disposal programme at the Belgian Nuclear Research Centre SCK/CEN is to propose, develop, and assess solutions for the safe disposal of radioactive waste. In Belgium, deep geological burial in clay is the primary option for the disposal of High-Level Waste and spent nuclear fuel. The main achievements during 1997 in the following domains are described: performance assessment, characterization of the geosphere, characterization of the waste, migration processes, underground infrastructure.

  3. Use of Information, Product Innovation and Financial Performance on Belgian Glasshouse Holdings

    OpenAIRE

    Taragola, Nicole; Huylenbroeck, Guido Van; Van Lierde, Dirk

    2002-01-01

    In order to meet the changing needs and preferences of consumers it will be important for Belgian glasshouse growers to change from a production-driven to a customer-driven strategy. More than ever, use of information and product innovation become critical factors in the changing competitive environment. The aim of the research is to analyse the relationship between business and managerial characteristics, use of information sources, product innovation and financial performance of the firm. T...

  4. Mafia Practices and Italian Entrepreneurial Activities in the Belgian Food Sector. Research Objectives

    OpenAIRE

    De Biase, Marco

    2014-01-01

    This research aims to study the social and economic processes which encourage the spread of mafia practices among some Italian entrepreneurs in the Belgian food sector. My working hypothesis is that mafia practices are violent and predatory strategies to monopolize the economic market, which rely on the use of heterogeneous and cross-class social networks. In this view, these activities of old and new Italian entrepreneurs in Belgium are not the result of the exportation of mafia methods thro...

  5. Geochemical behavior of trace elements in sub-tidal marine sediments of the Belgian coast

    OpenAIRE

    Gao, Y.; Lesven, L.; Gillan, D.; K Sabbe; Billon, G.; De Galan, S.; Elskens, M.; Baeyens, W.; Leermakers, M.

    2009-01-01

    High resolution profiles of trace elements (Fe, Mn, Co, As, Cu, Cr, Ni and Pb) were assessed using the DET (Diffusive Equilibrium in Thin films) and DGT (Diffusive Gradients in Thin films) techniques in silty, organically enriched, sub-tidal sediments of the Belgian coast during late winter and spring 2008. The general chemical properties of the sediments such as dissolved oxygen, pH, Eh and sulfide profiles, controlling precipitation/ mobilization reactions, were determined with electrodes (...

  6. New Belgian Law on Research on Human Embryos: Trust in Progress Through Medical Science

    OpenAIRE

    Pennings, G

    2003-01-01

    The new Belgian law on research on embryos in vitro accepts all types of research directed at therapeutic purposes and at increased medical knowledge. This includes research for germline and somatic gene therapy, therapeutic cloning, and the development of embryonic stem cell lines. As this presupposes the creation of embryos for research, this too is allowed. Other goals like sex selection for nonmedical reasons, eugenic practices and reproductive cloning are prohibited. In general, the law ...

  7. Recent changes in saving behaviour by Belgian households : the impact of uncertainty

    OpenAIRE

    Raïsa Basselier; Geert Langenus

    2014-01-01

    Belgian households save a lot in comparison to the average for the euro area. Recently, the household saving rate has shown large swings. During the great recession, it temporarily jumped to a record high but since then it has gradually fallen to record lows. Different factors of a structural or cyclical nature may account for these swings. The objective of the article is to gauge to what extent uncertainty related to the general economic outlook or households’ income prospects has contribute...

  8. Perceived work ability and turnover intentions: a prospective study among Belgian healthcare workers

    OpenAIRE

    Derycke, Hanne; Clays, Els; Vlerick, Peter; D'hoore, William; Hasselhorn, Hans Martin; Braeckman, Lutgart

    2012-01-01

    AIM: To report a study exploring prospective relations between nurses' perceived work ability and three forms of turnover intentions, respectively, intent to leave the ward, organization and profession. BACKGROUND: Turnover of nursing staff is a major challenge for healthcare settings and for healthcare in general, urging the need to improve retention. DESIGN: Survey. METHODS: Based on the longitudinal data of the Belgian sample from the European Nurses' Early Exit study, a total of 1531 heal...

  9. Joint Estimation of Mark-up and Bargaining Power Parameters for Belgian Manufacturing

    OpenAIRE

    Dobbelaere, Sabien

    2002-01-01

    This paper applies several extensions of Hall's (1988) methodology to analyse imperfections in both the product and the labour market for firms in the Belgian manufacturing industry over the period 1988-1995. We investigate (1) the heterogeneity in mark-up and bargaining power parameters among 17 sectors within the manufacturing industry, (2) whether higher bargaining power parameters are associated with higher mark-ups and (3) whether both parameters are influenced by cyclical and competitio...

  10. Signs of neurotoxicity in a Belgian Blue herd after ingestion of moulded silage

    OpenAIRE

    Guyot, Hugues; Sandersen, Charlotte; Brihoum, Mounir; Vandeputte, Sébastien; Rollin, Frédéric

    2011-01-01

    After ingestion of moulded beet pulp silage, cases of cerebro-cortical necrosis (CCN) and mortalities were observed in a dual purpose Belgian Blue (BB) herd. Contamination with Paecilomyces spp., a mould that produces byssochlamic acid, malformins and patulin, was proven. Twenty-five days after progressive introduction of beet pulp silage into the ration, most of the animals showed diminished appetite, excessive salivation and decreased milk production. Some of them showed a...

  11. Adaptation of the European crop growth monitoring system to the Belgian conditions.

    OpenAIRE

    Buffet, D.; Dehem, Didier; Wouters, K.; Tychon, Bernard; Oger, Robert; Veroustraete, F.

    1999-01-01

    The aim of the Belgian Crop Growth Monitoring System (B-CGMS) is the elaboration of an integrated information system predicting reliable, timely and objective estimates of crop yields and monitoring calamity sites at regional scales. Seven major crops are concerned by the project : winter wheat, winter barley, fodder maize, winter rape seed, potatoes, sugar beet and permanent meadow. The main tasks in the adaptation of the European model come down to the completion and the improvement of the ...

  12. An empirical study on human resource planning in Belgian production companies

    OpenAIRE

    Van den Bergh, Jorne; Belien, Jeroen; Hoskens, Brent

    2013-01-01

    This paper investigates human resource planning in Belgian production companies. First, a literature study is developed to serve as a basis for the results of the empirical research. The literature study is mainly based on papers in the field of operations research that provide interesting insights such as the research-application gap, which is the lack of implementation of models provided by literature. The most important part of this paper is the empirical research. The empirical research i...

  13. Salt water infiltration in two artificial sea inlets in the Belgian dune area

    OpenAIRE

    Vandenbohede, A.; Lebbe, L.; Gysens, S.; Delecluyse, K.; DeWolf, P.

    2008-01-01

    In the dune area of the Westhoek Nature Reserve, situated in the western Belgian coastal plain, two artificial tidal inlets were made aiming to enhance biodiversity. The infiltration of salt water in these tidal inlets was carefully monitored because a fresh water lens is present in the phreatic dune aquifer. This forms an important source of fresh water which is for instance exploited by a water company. The infiltration was monitored over a period of two years by means of electromagnetic bo...

  14. Psychological dimensions of unemployment: a gender comparison between Belgian and South African unemployed.

    OpenAIRE

    Yannick Griep; Sebastiaan Rothmann; Wouter Vleugels; Hans De Witte

    2012-01-01

    This study sought to compare South African and Belgian unemployed in their subjective experience of unemployment, committed towards employment and job search behaviour. We also considered gender differences regarding the psychological dimensions of unemployment between Belgium and South Africa. A cross-sectional survey design was used. Unemployed people were sampled from the Potchefstroom area in South Africa (N = 381) and the Brussels area in Belgium (N = 305). The Experiences of Unemploymen...

  15. Information Availability, Information Quality and the Financial Structure of Belgian SME's.

    OpenAIRE

    Van Campenhout, Geert; Van Caneghem, Tom

    2009-01-01

    In this paper we test whether the amount and/or quality of financial statement information affect the financial structure of Small and Medium Enterprises (SMEs). We explore this issue for Belgian SMEs because there are important differences in disclosure and audit requirements among them. Consistent with the traditional view that asymmetric or incomplete information restricts access to external funds, our results indicate that both the amount and the quality of financial statement information...

  16. Long-term changes in oil pollution off the Belgian coast: evidence from beached bird monitoring

    OpenAIRE

    Seys, J.; Offringa, H; P. Meire; Van Waeyenberge, J.; Kuijken, E.

    2002-01-01

    Trends in oil pollution in the southernmost (Belgian) part of the North Sea were analysed using a dataset of 37 years (1962-99) of annual national beached bird surveys conducted in February each year. The most abundant seabird groups represented in the beached birds were auks (31 %), gulls (28%), scoters (17%) and Kittiwake (9%). Oil rates of most bird species/taxa indicate a decline in oil pollution, though only Larus-gulls, Common Guillemot and Razorbill show significant reductions. The slo...

  17. Software support for manufacturing operations in Belgian SMEs: one size fits all?

    OpenAIRE

    Desmarey, Thierry; Degryse, Kris; Cottyn, Johannes

    2011-01-01

    Manufacturing companies face a big challenge to bridge the gap between their business and manufacturing processes. The urge to increase efficiency makes it necessary to align the business and manufacturing processes. Small and Medium-sized Enterprises (SMEs) experience several barriers to adopt software support for manufacturing operations. This paper gives an overview of a research study conducted in Belgian SMEs. The research studied the current adoption of software support for manufacturin...

  18. Sustainability of Global and Local Food Value Chains: An Empirical Comparison of Peruvian and Belgian Asparagus

    OpenAIRE

    Jana Schwarz; Monica Schuster; Bernd Annaert; Miet Maertens; Erik Mathijs

    2016-01-01

    The sustainability of food value chains is an increasing concern for consumers, food companies and policy-makers. Global food chains are often perceived to be less sustainable than local food chains. Yet, thorough food chain analyses and comparisons of different food chains across sustainability dimensions are rare. In this article we analyze the local Belgian and global Peruvian asparagus value chains and explore their sustainability performance. A range of indicators linked to environmental...

  19. Floating seaweed in the neustonic environment: a case study from Belgian coastal waters

    OpenAIRE

    Vandendriessche, S; Vincx, M.; Degraer, S.

    2007-01-01

    Floating seaweeds form the most important natural component of all floating material found on the surface of oceans and seas. Notwithstanding the absence of natural rocky shores, ephemeral floating seaweed clumps are frequently encountered along the Belgian coast. From October 2002 to April 2003, seaweed samples and control samples (i.e. surface water samples from a seaweed-free area) were collected every other week. Multivariate analysis on neustonic macrofaunal abundances showed significant...

  20. Using Firm-Level Data to Assess Gender Wage Discrimination in the Belgian Labour Market

    OpenAIRE

    Borowczyk Martins, Daniel; Vandenberghe, Vincent

    2010-01-01

    In this paper we explore a matched employer-employee data set to investigate the presence of gender wage discrimination in the Belgian private economy labour market. We identify and measure gender wage discrimination from firm-level data using a labour index decomposition pioneered by Hellerstein and Neumark (1995), which allows us to compare direct estimates of a gender productivity differential with those of a gender labour costs differential. We take advantage of the panel structure of the...

  1. Firm-level Evidence on Gender Wage Discrimination in the Belgian Private Economy

    OpenAIRE

    Vandenberghe, Vincent

    2011-01-01

    In this paper we explore a matched employer-employee data set to investigate the presence of gender wage discrimination in the Belgian private economy labour market. Contrary to many existing papers, we analyse gender wage discrimination using an independent productivity measure. Using firm-level data, we are able to compare direct estimates of a gender productivity differential with those of a gender wage differential. We take advantage of the panel structure to identify gender-related diffe...

  2. Grid Integration of Large-scale Wind Turbines Equipped With Full Converters: Belgian Case Study

    OpenAIRE

    De Rijcke, Simon; Ergun, Hakan; De Vos, Kristof; Driesen, Johan

    2011-01-01

    This paper describes the results of a study regarding the integration of wind power into the Belgian electricity system. The main focus of this study is the contribution of wind power plants to reduce voltage deviations due to load and wind power variations. It is shown, how wind power plants can maintain and improve the voltage in the existing electricity network using their reactive power operation characteristics. To cover a broad variety of study cases, two different locations with differ...

  3. RV Belgica II: The new Belgian research vessel to replace the existing RV A962 Belgica

    OpenAIRE

    Naudts, L.; Cox, D.; Roose, P.; Monteny, F.

    2014-01-01

    For 30 years RV Belgica has been the marine infrastructure for Belgian marine scientists working on the Belgian Part of the North Sea and in the marine realm stretching from Norway, over Ireland to Morocco. Even if the ship is still performing research activities for more than 180 days per year, the increasing number of technical breakdowns and the rising maintenance cost associated with her age makes the replacement by a new RV Belgica II a necessity for the Belgian marine science community.

  4. Microbial diversity and metabolite composition of Belgian red-brown acidic ales.

    Science.gov (United States)

    Snauwaert, Isabel; Roels, Sanne P; Van Nieuwerburg, Filip; Van Landschoot, Anita; De Vuyst, Luc; Vandamme, Peter

    2016-03-16

    Belgian red-brown acidic ales are sour and alcoholic fermented beers, which are produced by mixed-culture fermentation and blending. The brews are aged in oak barrels for about two years, after which mature beer is blended with young, non-aged beer to obtain the end-products. The present study evaluated the microbial community diversity of Belgian red-brown acidic ales at the end of the maturation phase of three subsequent brews of three different breweries. The microbial diversity was compared with the metabolite composition of the brews at the end of the maturation phase. Therefore, mature brew samples were subjected to 454 pyrosequencing of the 16S rRNA gene (bacteria) and the internal transcribed spacer region (yeasts) and a broad range of metabolites was quantified. The most important microbial species present in the Belgian red-brown acidic ales investigated were Pediococcus damnosus, Dekkera bruxellensis, and Acetobacter pasteurianus. In addition, this culture-independent analysis revealed operational taxonomic units that were assigned to an unclassified fungal community member, Candida, and Lactobacillus. The main metabolites present in the brew samples were L-lactic acid, D-lactic acid, and ethanol, whereas acetic acid was produced in lower quantities. The most prevailing aroma compounds were ethyl acetate, isoamyl acetate, ethyl hexanoate, and ethyl octanoate, which might be of impact on the aroma of the end-products. PMID:26802571

  5. Last developments in the Belgian disposal programme for low and intermediate short-lived waste

    International Nuclear Information System (INIS)

    After an historical reminder of the several phases of the Belgian program for the disposal of low and medium level short-lived waste since the creation of ONDRAF/NIRAS and the bad results obtained in the 90's by using a pure technical approach, the presentation will explain the main lines of the new methodology developed, as a consequence of the government decision of 16 January 1998 in ONDRAF/NIRAS to improve local acceptance for the disposal project. The way local partnerships were created with four nuclear municipalities under the form of a non-profit organization with a clear mission, the functioning, on a voluntary base, of the different partnerships during four to six years and the concrete results obtained until now using this very innovative method will be addressed. The last developments of the Belgian program for the disposal of low and medium level and short-lived waste will be presented, including the recent and very important decision of the Belgian government of 23 June 2006 to dispose of the low and medium active short-lived waste in a surface disposal installation on the territory of the municipality Dessel. (author)

  6. Air crew exposure on board of long-haul flights of the Belgian airlines

    International Nuclear Information System (INIS)

    New European radiation protection recommendations state that measures need to be taken for flight crew members whose annual radiation exposure exceeds 1 mSv. This will be the case for flight crew members who accumulate most of their flying hours on long-haul flights. The Recommendations for the Implementation of the Basic Safety Standards Directive states that for annual exposure levels between 1 and 6 mSv individual dose estimates should be obtained, whereas for annual exposures exceeding 6 mSv, which might rarely occur, record keeping with appropriate medical surveillance is recommended. To establish the exposure level of Belgian air crews, radiation measurements were performed on board of a total of 44 long-haul flights of the Belgian airlines. The contribution of low linear energy transfer (LET) radiation (photons, electrons, protons) was assessed by using TLD-700H detectors. The exposure to high-LET radiation (mostly neutrons) was measured with bubble detectors. Results were compared to calculations with an adapted version of the computer code CARI. For the low-LET radiation the calculations were found to be in good agreement with the measurements. The measurements of the neutron dose were consistently lower than the calculations. With the current flight schedules used by the Belgian airlines, air crew members are unlikely to receive annual doses exceeding 4 mSv. (author)

  7. Predicting the environmental risks of radioactive discharges from Belgian nuclear power plants

    International Nuclear Information System (INIS)

    An environmental risk assessment (ERA) was performed to evaluate the impact on non-human biota from liquid and atmospheric radioactive discharges by the Belgian Nuclear Power Plants (NPP) of Doel and Tihange. For both sites, characterisation of the source term and wildlife population around the NPPs was provided, whereupon the selection of reference organisms and the general approach taken for the environmental risk assessment was established. A deterministic risk assessment for aquatic and terrestrial ecosystems was performed using the ERICA assessment tool and applying the ERICA screening value of 10 μGy h−1. The study was performed for the radioactive discharge limits and for the actual releases (maxima and averages over the period 1999–2008 or 2000–2009). It is concluded that the current discharge limits for the Belgian NPPs considered do not result in significant risks to the aquatic and terrestrial environment and that the actual discharges, which are a fraction of the release limits, are unlikely to harm the environment. -- Highlights: • Impact of radioactive discharges by the Belgian NPPs of Doel and Tihange on wildlife was evaluated. • Deterministic risk assessment for aquatic and terrestrial ecosystems performed with the ERICA tool. • NPP discharge limits do not result in significant risks to the aquatic and terrestrial environment. • Actual discharges, a fraction of the release limits, are unlikely to harm the environment

  8. Belgian canine population and purebred study for forensics by improved mitochondrial DNA sequencing.

    Science.gov (United States)

    Desmyter, Stijn; Gijsbers, Leonie

    2012-01-01

    In canine population studies for forensics, the mitochondrial DNA is profiled by sequencing the two hyper variable regions, HV1 and HV2 of the control region. In a first effort to create a Belgian population database some samples showed partially poor sequence quality. We demonstrated that a nuclear pseudogene was co-amplified with the mtDNA control region. Using a new combination of primers this adverse result was no longer observed and sequencing quality was improved. All former samples with poor sequence data were reanalyzed. Furthermore, the forensic canine population study was extended to 208 breed and mixed dogs. In total, 58 haplotypes were identified, resulting in an exclusion capacity of 0.92. The profile distribution of the Belgian population sample was not significantly different from those observed in population studies of three other countries. In addition to the total population study 107 Belgian registered pedigree dogs of six breeds were profiled. Per breed, the obtained haplotypes were supplemented with those from population and purebred studies. The combined data revealed that some haplotypes were more or less prominent present in particular dog breeds. The statistically significant differences in haplotype distribution between breeds and population sample can have consequences on mtDNA databasing and matching probabilities in forensics. PMID:21489897

  9. Obesity, weight gain, and ovarian cancer risk in African American women.

    Science.gov (United States)

    Bandera, Elisa V; Qin, Bo; Moorman, Patricia G; Alberg, Anthony J; Barnholtz-Sloan, Jill S; Bondy, Melissa; Cote, Michele L; Funkhouser, Ellen; Peters, Edward S; Schwartz, Ann G; Terry, Paul; Schildkraut, Joellen M

    2016-08-01

    Although there is growing evidence that higher adiposity increases ovarian cancer risk, little is known about its impact in African American (AA) women, the racial/ethnic group with the highest prevalence of obesity. We evaluated the impact of body mass index (BMI) 1 year before diagnosis and weight gain since age 18 years on ovarian cancer risk in a population-based case-control study in AA women in 11 geographical areas in the US. Cases (n = 492) and age and site matched controls (n = 696) were identified through rapid case ascertainment and random-digit-dialing, respectively. Information was collected on demographic and lifestyle factors, including self-reported height, weight at age 18 and weight 1 year before diagnosis/interview. Multivariable logistic regression was used to compute odds ratios (OR) and 95% confidence intervals (CI), adjusting for potential covariates. Obese women had elevated ovarian cancer risk, particularly for BMI ≥ 40 kg/m(2) compared to BMI <25 (OR = 1.72, 95% CI: 1.12-2.66; p for trend: 0.03). There was also a strong association with weight gain since age 18 (OR: 1.52; 95% CI: 1.07-2.16; p for trend: 0.02) comparing the highest to lowest quartile. In stratified analyses by menopausal status, the association with BMI and weight gain was limited to postmenopausal women, with a 15% (95% CI: 1.05-1.23) increase in risk per 5 kg/m(2) of BMI and 6% (95% CI: 1.01-1.10) increase in risk per 5 kg of weight gain. Excluding hormone therapy users essentially did not change results. Obesity and excessive adult weight gain may increase ovarian cancer risk in post-menopausal AA women. PMID:27038123

  10. Reference Ranges for Bone Mineral Density and Prevalence of Osteoporosis in Vietnamese Men and Women

    Directory of Open Access Journals (Sweden)

    Nguyen Nguyen D

    2011-08-01

    Full Text Available Abstract Background The aim of this study was to examine the effect of different reference ranges in bone mineral density on the diagnosis of osteoporosis. Methods This cross-sectional study involved 357 men and 870 women aged between 18 and 89 years, who were randomly sampled from various districts within Ho Chi Minh City, Vietnam. BMD at the femoral neck, lumbar spine and whole body was measured by DXA (Hologic QDR4500. Polynomial regression models and bootstraps method were used to determine peak BMD and standard deviation (SD. Based on the two parameters, we computed T-scores (denoted by TVN for each individual in the study. A similar diagnosis was also done based on T-scores provided by the densitometer (TDXA, which is based on the US White population (NHANES III. We then compared the concordance between TVN and TDXA in the classification of osteoporosis. Osteoporosis was defined according to the World Health Organization criteria. Results In post-menopausal women, the prevalence of osteoporosis based on femoral neck TVN was 29%, but when the diagnosis was based on TDXA, the prevalence was 44%. In men aged 50+ years, the TVN-based prevalence of osteoporosis was 10%, which was lower than TDXA-based prevalence (30%. Among 177 women who were diagnosed with osteoporosis by TDXA, 35% were actually osteopenia by TVN. The kappa-statistic was 0.54 for women and 0.41 for men. Conclusion These data suggest that the T-scores provided by the Hologic QDR4500 over-diagnosed osteoporosis in Vietnamese men and women. This over-diagnosis could lead to over-treatment and influence the decision of recruitment of participants in clinical trials.

  11. Depression after low-energy fracture in older women predicts future falls: a prospective observational study

    Directory of Open Access Journals (Sweden)

    van den Berg Martha

    2011-11-01

    Full Text Available Abstract Background Falls are one of the main causes of fractures in elderly people and after a recent fracture, the risk of another fall is increased, resulting in subsequent fracture. Therefore, risk factors for future falls should be determined. We prospectively investigated the relationship between depression and the incidence of falls in post-menopausal women after a low-energy fracture. Methods At baseline, 181 women aged 60 years and older who presented with a recent low-energy fracture were evaluated at the fracture and osteoporosis outpatient clinics of two hospitals. As well as clinical evaluation and bone mineral density tests, the presence of depression (measured using the Edinburgh Depression Scale, EDS, depression cut-off > 11 and risk factors for falling were assessed. During two years of follow-up, the incidence of falls was registered annually by means of detailed questionnaires and interviews. Results Seventy-nine (44% of the women sustained at least one fall during follow-up. Of these, 28% (n = 22 suffered from depression at baseline compared to 10% (n = 10 of the 102 women who did not sustain a fall during follow-up (Χ2 = 8.76, df = 1, p = .003. Multiple logistic regression showed that the presence of depression and co-morbidity at baseline were independently related to falls (OR = 4.13, 95% CI = 1.58-10.80; OR = 2.25, 95% CI = 1.11-4.56, respectively during follow-up. Conclusions The presence of depression in women aged 60 years and older with recent low-energy fractures is an important risk factor for future falls. We propose that clinicians treating patients with recent low-energy fractures should anticipate not only on skeletal-related risk factors for fractures, but also on fall-related risk factors including depression.

  12. Are women who are taking Hormone Replacement Therapy doing so with informed consent?

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, E.M

    2003-11-01

    Just over half the population in Britain today are women, and each is likely to spend over one-third of her life in the post menopausal state. The number of post-war 'Baby Boomers' is having a profound effect on interest in the menopause and increasing awareness of Hormone Replacement Therapy (HRT). Patients are no longer prepared to passively accept the advice of their doctor, and should make an informed decision over its use, after having been given up-to-date information. Some of the claimed benefits of taking HRT are not fully proven and the risks and disadvantages must be considered, notably the increased risk of breast cancer and the effect on the sensitivity and specificity of the mammographic image. The long-term benefits are still uncertain. Available information needs to be comprehensible, credible, and up to date. Whether to initiate the taking of HRT is one of the most important decisions a woman entering mid-life will make, so she needs to be given information she can understand in order to make an informed decision. HRT and informed consent are topics relevant to mammography, which was the rationale in writing this paper as part of a Post Graduate Certificate in Mammographic Studies.

  13. Association of a single nucleotide polymorphism at 6q25.1,rs2046210, with endometrial cancer risk among Chinese women

    Institute of Scientific and Technical Information of China (English)

    Guoliang Li; Qiuyin Cai; Yong-Bing Xiang; Regina Courtney; Jia-Rong Cheng; Bo Huang; Ji-Rong Long; Hui Cai; Wei Zheng; Xiao-Ou Shu

    2011-01-01

    A recent genome-wide association study identified a new susceptibility locus for breast cancer, rs2046210, which is a single nucleotide polymorphism (SNP) located upstream of the estrogen receptor α (ESR1) gene on chromosome 6q25.1. Given that endometrial cancer shares many risk factors with breast cancer and both are related to estrogen exposure and that rs2046210 is in close proximity to the ESR1 gene, we evaluated the association of SNP rs2046210 with endometrial cancer risk among 953 cases and 947 controls in a population-based, case-control study conducted in Shanghai, China. Logistic regression models were used to derive odds ratios (ORs) and 95% confidence intervals (95% Cis) after adjusting for potential confounders. We found that the A allele of rs2046210, linked to an increased risk of breast cancer, was associated with increased but not statistically significant risk of endometrial cancer (OR = 1.16, 95% CI = 0.96-1.41 for the GA and AA genotypes compared with the GG genotype); the association was stronger among post-menopausal women (OR = 1.28, 95% CI = 1.00-1.65). The association tended to be stronger among women with higher or longer estrogen exposure than among women with relatively lower or shorter exposure to estrogen. Our study suggests that rs2046210 may play a role in the etiology of endometrial cancer. Additional studies are needed to confirm our findings.

  14. Evaluation of the Relationship between 5-HTT and MAO Gene Polymorphisms, Mood and Level of Anxiety among Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Elżbieta Grochans

    2014-12-01

    Full Text Available Objective: The aim of this study was to analyze how mood and anxiety level are related to the functional genetic polymorphism in the promoter region of SLC6A4 (5-HTTLPR and the 30-bp VNTR polymorphism in the MAO A promoter region. Methods: The study involved 272 postmenopausal women from Poland. The authors employed the State-Trait Anxiety Inventory for measuring levels of anxiety, the Mood Adjective Check List for measuring mood, and genetic tests. Results: Analysis did not show any statistically significant differences in the mean levels of anxiety, and mood disorders in women in relation to genotypes of the 5-HTTLPR (SLC6A4 polymorphism and the 30-bp VNTR polymorphism in the MAO A promoter region. However, these problems were more severe among women with s/s genotype. In the case of MAO A gene polymorphism, the level of anxiety was higher in women with a 4/4 genotype. Conclusions: The study did not prove the possibility of the identification of homogeneous groups of women with an elevated risk of developing anxiety and mood disorders during the post-menopausal period. Nevertheless, it showed that respondents with s/s genotype of the 44-bp polymorphism in the 5-HTT (SLC6A4 promoter region had the highest average anxiety levels both as a state and as a trait. Furthermore, the analysis of the 30-bp VNTR polymorphism in the MAO A promoter region demonstrated slight differences in anxiety levels between the women, indicating that those with a 4/4 genotype had higher severity of anxiety symptoms.

  15. A STUDY OF CLINICAL PROFILE OF ISCHEMIC HEART DISEASE AMONG SOUTH INDIAN WOMEN IN A TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Lokesh

    2015-05-01

    Full Text Available INTRODUCTION : Our study was done to study in detail the clinical profile of cases admitted with ischemic heart diseases in women at ICCU VIMS Bellary . Objectives : are. (1 To study the clinical profile of ischemic heart diseases in women. ( 2 To identify the influence of well - defined risk factors in wome n with ischemic heart diseases. (3 To identify if there are any risk factors specific to wom en with ischemic heart diseases. MATERIAL AND METHODS : Ours is a clinical , prospective , observational and open study. The study subjects were women admitted in Intensive Coronary Care Unit of Vijayanagara institute of medical sciences hospital , Bellary with signs and symptoms suggestive of ischemic heart diseases. After obtaining a detailed history and clinical examinati on the patients were subjected to relevant investigations. The complete data was collected in specially designed case recording form and transferred into a Master chart which is then subjected to statistical analysis. RESULTS AND DISCUSSION : We studied 100 cases of ischemic heart diseases in women , out of which 82 patients presented with Acute MI , 14 patients with Unstable angina and 4 patients with stable angina , most of which were observed in post - menopausal women. Prognosis was good in patients who recei ved intensive care within 6 hours of onset of symptoms. Chest pain was the most common symptom of presentation. CONCLUSION : Our study had highlighted the fact that ischemic heart disease no longer remains gender neutral and has been found to be a principle killer in women and they suffer from IHD on account of preventable diseases like hypertension , diabetes mellitus , obesity. KEYWORDS : Ischemic heart disease ; Hypertension ; Acute MI ; Unstable angina.

  16. The effects of ethinylestradiol and progestins ("the pill") on cognitive function in pre-menopausal women.

    Science.gov (United States)

    Gogos, Andrea; Wu, YeeWen Candace; Williams, Amy S; Byrne, Linda K

    2014-12-01

    Oral contraceptives (OCs), often referred to as "the pill", are the most commonly employed form of reversible contraception. OCs are comprised of combined synthetic estrogen and progestin, which work to suppress ovulation and subsequently protect against pregnancy. To date, almost 200 million women have taken various formulations of OC, making it one of the most widely consumed classes of medication in the world. While a substantial body of literature has been dedicated to understanding the physical effects of OCs, much less is known about the long term consequences of OC use on brain anatomy and the associated cognitive effects. Accumulating evidence suggests that sex hormones may significantly affect human cognition. This phenomenon has been commonly studied in older populations, such as in post-menopausal women, while research in healthy, pre-menopausal women remains limited. The current review focused on the effects of OCs on human cognition, with the majority of studies comparing pre-menopausal OC users to naturally cycling women. Human neuroimaging data and animal studies are also described herein. Taken together, the published findings on OC use and human cognition are varied. Of those that do report positive results, OC users appear to have improved verbal memory, associative learning and spatial attention. We recommend future research to employ blinding procedures and randomised designs. Further, more detailed information pertaining to the specific generation and phasic type of OCs, as well as menstrual cycle phase of the OC non-users should be considered to help unmask the potential impact of OC use on human cognition. PMID:25266552

  17. Adapting to the System or the Student? Exploring Teacher Adaptations to Disadvantaged Students in an English and a Belgian Secondary School

    Science.gov (United States)

    Stevens, Peter A. J.; Van Houtte, Mieke

    2011-01-01

    This article builds on research on teacher adaptations to students by exploring how Belgian and English national contexts influence teachers' definitions of educational success, their explanations of educational failure, and their allocation of scarce educational resources to disadvantaged students. Ethnographic data from one Flemish (Belgian) and…

  18. The Belgian nuclear higher education network: the evolution of an academic programme in nuclear engineering

    International Nuclear Information System (INIS)

    The master-after-master in nuclear engineering provided by the Belgian Nuclear higher Education Network (BNEN) is a one-year, 60 ECTS programme which combines the expertise of six Belgian universities and SCK.CEN, the Belgian Nuclear Research Centre, which participates through its Academy for Nuclear Science and Technology. It was created in close collaboration with representatives of academia, research centres, industry and other nuclear stakeholders. The BNEN consortium Due to its modular programme, BNEN is accessible for both full-time students (mainly young engineering graduates) as well as young professionals already employed in the nuclear industry. The programme is offered in English to facilitate the participation of international students. One of the important aspects of the BNEN programme is the fact that exercises and hands-on sessions in the specialised laboratories of SCK.CEN complement the theoretical classes to bring the students into contact with all facets of nuclear energy. Several of SCK.CEN's researchers provide valuable contributions to the programme through seminars and practical exercises. From their daily practices and responsibilities they give an expert view on the subjects that are being taught. In 2012, in the framework of an official accreditation process all aspects of the BNEN programme were audited by an international visitation panel. The most important outcome of this process is the current reform of the academic programme, which will be implemented in the academic year 2014-2015, taking into account the recommendations by the visitation panel. In this paper, the history of the BNEN programme will be discussed, the new BNEN programme will be presented as well as the process that has led to its implementation. (authors)

  19. Life cycle modeling of energy matrix scenarios, Belgian power and partial heat mixes as case study

    International Nuclear Information System (INIS)

    Highlights: ► An LCA modeling approach is proposed for energy systems. ► A simplified Belgian energy system with and without nuclear power is optimized. ► A sustainability pathway is obtained from successive scenario optimizations. ► Reduction of GWP without nuclear power is limited under modeled conditions. ► Biomass potential implies an increase of toxicity and land occupation indicators. - Abstract: The present paper introduces a life cycle modeling approach for representing actual demand of energy or energy intensive products delivered within a system (electricity, heat, etc.) for optimization of the energy mix, according to some of the available life cycle impact assessments (LCIAs). Unlike classical LCA modeling approach, the real amount of several energy products leaving the system and the interactions due to the presence of multi-output processes are considered within the present approach. As a case study, future scenarios are obtained for the Belgian electricity mix production and the heat mix potentially substituted by CHP or biomass, switching between abandoning or not power from nuclear energy. The possibility of using natural gas, biomass for cogeneration, wind power and solar photovoltaic energy are considered within the availability ranges of these resources. Finally, results are presented from successive optimizations according to the sustainability potential defined in a previous paper. A pathway to a more sustainable Belgian energy system is obtained. Finally it is concluded that under the modeling conditions and without nuclear energy it is not possible to obtain a reduction of GHGs and despite diminishing of non-renewable resource consumption, a rising of toxicity is obtained

  20. Quality assurance of automatic exposure control devices for digital radiography: Belgian approach

    International Nuclear Information System (INIS)

    Since 2001, an annual quality control of medical X-ray equipment by a medical physics expert (MPE) is obligatory in Belgium. The minimal standards that a system should achieve are defined in the RP91 document. After some years of experience, there was a consensus that the MPE activities would benefit from a more explicit text that would take full account of the challenges of the on-going digitization. A working group of Belgian physicists was formed within the Belgian Hospital Physicists Association to create a more extended and detailed protocol, to harmonize the test procedures among the physicists and to test digital detectors appropriately. The aim of the group was to make sure that image quality and patient dose are well balanced and that the automatic exposure controller functions well for all conditions of beam quality and patient thickness. The most important chapter of the new Belgian protocol concerns the testing of the AEC for digital radiography detectors (DR) and computed radiography plates (CR). These tests are not described in the RP91. Conventional X-ray systems using film radiography have to give similar optical densities. On digital systems, the optical density is fixed by the processing and not at all related to exposure. The approaches to test film-screen can therefore not be applied to digital detectors. The hypothesis of the test procedure is the following: as the image quality of a digital detector is not contrast limited but dose limited, it is the amount of noise in the image which limits the image quality. Therefore, the goal of the AEC calibration should be to keep the SNR constant at all thicknesses and beam qualities. As described by Doyle and Martin, we aim to control the SNR by measuring the exposure indication (EI) or pixel value (PV) of the detector. We report on a practical approach, that has been developed in our team

  1. Influence of dabigatran and rivaroxaban on routine coagulation assays. A nationwide Belgian survey.

    Science.gov (United States)

    Van Blerk, Marjan; Bailleul, Els; Chatelain, Bernard; Demulder, Anne; Devreese, Katrien; Douxfils, Jonathan; Jochmans, Kristin; Mullier, François; Wijns, Walter; Soumali, Mohamed Rida; Coucke, Wim; Vernelen, Kris; Van de Walle, Philippe

    2015-01-01

    The Belgian national External Quality Assessment Scheme performed a nationwide survey using lyophilised plasma samples spiked with dabigatran or rivaroxaban to demonstrate to the Belgian clinical laboratories how these drugs affect their routine coagulation assays prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen and antithrombin. Virtually all Belgian laboratories performing routine coagulation testing (189/192) participated in the survey. Both, dabigatran and rivaroxaban significantly prolonged the PT and aPTT in a concentration- and reagent-dependent manner. PT reagents were more influenced by rivaroxaban than by dabigatran and aPTT reagents more influenced by dabigatran than by rivaroxaban. Among PT reagents, Neoplastin R® was the most sensitive to rivaroxaban and Innovin® and Thromborel S® the least sensitive. Converting PT results to INR only increased the variability between reagents. Among aPTT reagents, Actin FSL® was the least sensitive to dabigatran while the other aPTT reagents showed slightly higher sensitivities. The presence of dabigatran led to falsely reduced fibrinogen concentrations when measured with a low thrombin concentration reagent. The presence of dabigatran caused an overestimation of the antithrombin level when measured with a thrombin-based activity assay and the presence of rivaroxaban an overestimation of the antithrombin level when measured with a FXa-based assay. Instrument-related differences were found for all tested parameters. In conclusion, this paper provides detailed information on the effect of dabigatran and rivaroxaban on routine coagulation assays as performed with a large number of reagent/instrument combinations. PMID:25231101

  2. New trends in the Belgian programme on nuclear air cleaning technology

    International Nuclear Information System (INIS)

    In the Belgian Programme on nuclear air cleaning technology the Mercurex process has been developed to trap iodine compounds from dissolver off-gases. Krypton is removed with the help of a cryogenic distillation unit. The various gas cleaning units have been integrated in a gas purification test loop for dissolver off-gas at a through put of 25 m3 gas h-1. The separation of tritium from liquid reprocessing effluents is being developed according to the ELEX-process. New research is started on the capture of semi-volatile ruthenium compounds

  3. Contamination levels observed on the Belgian territory subsequent to the Chernobyl accident

    International Nuclear Information System (INIS)

    A summary of the data from different laboratories concerning the fallout on the Belgian territory following the Chernobyl emissions is presented. The evolution of the particulate air activity at ground level, the integrated fallout captured in water, the deposition on soil surface directly for different localities in Belgium are given. The grass contamination, the milk contamination from individual farms, the concentration levels on leafy vegetables, surface waters and water basins and the contamination of meat during the month of May are presented. (A.F.)

  4. Hundred and eighty years of fleet dynamics in the Belgian sea fisheries

    OpenAIRE

    Lescrauwaet, A.-K.; Fockedey, N.; Debergh, H.; Vincx, M.; Mees, J.

    2013-01-01

    Understanding the impact of fisheries on the commercial fish stocks requires detailed catch statistics and data on the dynamics of fleet and catch effort, at least before industrial fishing started. Most time-series on the fleet dynamics start after the 1980s, at times when major changes in fleet characteristics had already taken place. In the present paper, the results of the integration of data on fleet size (from 1830), tonnage (from 1842) and engine power (kW, from 1912) of the Belgian se...

  5. Determining the marketing mix for a start-up travel agency aimed at the Belgian market

    OpenAIRE

    Hanák, Marek

    2014-01-01

    This thesis suggests a marketing mix consisting of 4 P's for a start-up travel agency. It created a product according to the quantitative research, n=140, and a qualitative research on the Belgian market. It includes the price of the product according to a competitor analysis, price expectation of the segment and a calculation of all costs connected with providing the service. It suggests also a promotion strategy aimed at the target audience and describes the place in terms point of sale ded...

  6. Modelling of density dependent groundwater flow in the south-western Belgian coastal plain

    OpenAIRE

    Vandenbohede, A.; Linster, T.; Lebbe, L.

    2005-01-01

    The study area is situated at the landward border of the Belgian western coastal plain at the right bank of the river Ijzer. The phreatic aquifer is of quaternary age. Until about the 12th century, the hydrology of the area was influenced by the North Sea. The area was criss-crossed by tidal channels and gullies and the aquifer was mainly filled with salt water. From about 1100 AD, the area was gradually reclaimed, halting the influence of the sea. The channels silted up. Fresh water started ...

  7. Methods used to seismically upgrade. The safety related components of Belgian plants

    International Nuclear Information System (INIS)

    Belgian nuclear power amounts to about 6,000 MW, generated by seven plants that started operation as early as 1967. The latest plant started in 1985. Some of these plants were designed with no seismic requirements whatsoever. Even for those that had seismic requirements at the design stage, seismic demand was raised after design had been frozen (late during construction or at the 10 years revision). As a consequence all the plants had to undergo, to a variable extent, a seismic reevaluation and/or backfitting. Civil structures were concerned as well as electro-mechanical equipment and piping systems. The present paper deals with the mechanical aspect of the problem (equipment and piping). In order to minimize hardware modifications, advanced analytical techniques were used throughout the process, starting with the elaboration of a site specific spectrum, and using a full soil-structure interaction in order to get as 'realistic' as possible floor response spectra. In some instances, non linear elasto-plastic time history analysis was performed on piping-systems in order to qualify them without hardware modifications. In other cases a 'Load Coefficient Method' was used. Sometimes stresses or displacements taken from the original stress reports and scaled by comparison of applicable spectra, allowed to assess the seismic validity of the system under investigation. Seismic acceptability of installed active equipment is more difficult to demonstrate, as this is usually done by testing. This problem is a generic issue in the US, identified under the label USI-A-46 (Unresolved Safety Issue). It is treated by. a group of Utilities (SQUG = Seismic Qualification Utilities Group). The Belgian Utility is member of that group since 1985. The application of this program is starting in the US. SQUG methodology has been applied to three Belgian plants starting in 1988 and is now completed. The required fixes are being implemented. Experience gained in the process has been applied

  8. Lessons learned from the decommissioning of the Belgian pressurized water test reactor BR3

    International Nuclear Information System (INIS)

    The BR3 plant was operated with the main objective of testing advanced PWR fuels under irradiation conditions similar to those encountered in large commercial PWR plants. In 1989, it was selected as one of the pilot projects of the European Commission for its R and D programme on Decommissioning of nuclear installations. With the decommissioning of the BR3 reactor, the Belgian Nuclear Research Centre SCK·CEN gained a lot of experiences in the field of decommissioning. This paper describes the main phases carried out in the decommissioning project up till now and will discuss the main lessons to learn. (author)

  9. How frequently do prices change? Evidence based on the micro data underlying the Belgian CPI

    OpenAIRE

    Aucremanne, Luc; Dhyne, Emmanuel

    2004-01-01

    This paper examines the degree of price rigidity in Belgian consumer prices, using a large database. As to the observed degree of rigidity, the results reveal a substantial amount of heterogeneity, not only across but also within product categories. While prices turn out to be perfectly flexible for some product categories, they tend to be very sticky for others. Each month, nearly 17 p.c. of the consumer prices change on average and the median duration of a price spell is close to 13 months....

  10. Taxes and Corporate Financing Decisions – Evidence from the Belgian ACE Reform

    OpenAIRE

    aus dem Moore, Nils

    2014-01-01

    We contribute to the empirical literature on the debt bias of corporate income taxation through a micro-econometric evaluation of the so-called ACE corporate tax reform in Belgium based on firm-level accounting data. We interpret the tax reform that came into effect in January 2006 as an economic quasi experiment. We identify its causal impact on the leverage ratio of Belgian corporations by means of a difference-in-differences (DiD) approach, using corporations from the UK as comparison grou...

  11. Experiences with a continuous vibration monitoring system on rotating machines in the Belgian power plants

    International Nuclear Information System (INIS)

    Since the availability of turbogenerators is very important, especially for nuclear plants, some Belgian power plants asked Laborelec to develop a better vibration monitoring with analysis capabilities and the possibility to record data. The main goal was to have a better insight in the vibrational behaviour of some critical machines and to limit the outages due to vibrational problems. The first prototype of a computerised monitoring system was installed in 1985 to survey the Doel 4 turbine from the beginning. Meanwhile 39 turbines have been equipped ranging from 125 MW, 25 years old, fossil fuel plants to large 1000 MW nuclear plants. Some reactor coolant pumps were instrumented too. (orig.)

  12. Hormonal exposures and the risk of intracranial meningioma in women: a population-based case-control study

    International Nuclear Information System (INIS)

    The role of exogenous hormone exposures in the development of meningioma is unclear, but these exposures have been proposed as one hypothesis to explain the over-abundance of such tumors in women. The association between oral contraception (OC) or hormone replacement therapy (HRT) and intracranial meningioma in women was investigated using a population-based, matched case-control study. Exposures for 143 cases and 286 controls matched on age within five years were obtained by interview. Diagnoses were confirmed histopathologically and estrogen and progesterone receptor assays conducted. Although risk of meningioma appeared modestly elevated in past OC users (OR = 1.5, 95% CI 0.8 – 2.7), and in current users (OR = 2.5, 95% CI 0.5 – 12.6), the confidence intervals were wide. No significant association between meningioma risk and duration of OC use was found. Likewise, risk of meningioma was only weakly associated with past use of HRT (OR = 0.7, 95% CI 0.4 – 1.3), and not at all with current use of HRT (OR = 1.0, 95% CI 0.5 – 2.2). Of 142 available specimens, 2 (1%) expressed estrogen receptors, whereas 130 (92%) expressed progesterone receptors (PR). OC use was associated with increased risk of a meningioma expressing less rather than more PR (OR = 3.2, 95% CI 1.3 – 8.0). Overall, in post menopausal women, HRT use appeared to confer a non-significant protective effect, and was not associated with low or high PR expressing meningiomas. This study found little evidence of associations between meningioma and exogenous hormone exposures in women but did suggest that some hormonal exposures may influence tumor biology in those women who develop meningioma

  13. Application of the CALUX bioassay for epidemiological study. Analyses of Belgian human plasma

    Energy Technology Data Exchange (ETDEWEB)

    Wouwe, N. van; Debacker, N.; Sasse, A. [Scientific Institute of Public Health, Brussels (BE)] (and others)

    2004-09-15

    The CALUX bioassay is a promising screening method for the detection of dioxin-like compounds. The observed good sensitivity, low number of false negative results as well as the good correlations with the GC-HRMS TEQ-values in case of feed and food analyses allow this method to climb in the first assessment methods' scale. The low amount of sample needed in addition to those latest advantages suggest that the CALUX bioassay could be a good screening method for epidemiological studies. The Belgian epidemiological study concerning the possible effect of the dioxin incident on the body burden of the Belgian population was an opportunity to test this method in comparison to the gold reference one: the GC-HRMS. The first part of this abstract presents epidemiological parameters (sensibility, specificity,) of the CALUX bioassay using CALUX TEQ-values as estimators of the TEQ-values of the 17 PCDD/Fs. The second part examines epidemiological determinants observed for CALUX and GCHRMS TEQ-values.

  14. Different Regional Approaches to Cultural diversity Interpreting the Belgian Cultural Diversity Policy Paradox

    Directory of Open Access Journals (Sweden)

    Ilke Adam

    2015-11-01

    Full Text Available In Belgium, the authority over cultural diversity policies resulting from immigration has been devolved from the central state to the regions since 1970. Consequently, Flanders and Francophone Belgium have progressively developed divergent policy tools. By describing the divergent evolution of Francophone and Flemish cultural diversity policies, our paper demonstrates the existence of a “Belgian Cultural Diversity Paradox”, namely the existence of more multicultural minority rights in the region that has most experienced electoral success by an extreme-right anti-immigrant party (Flanders, and a more colour blind and radical secular approach in the region where anti-immigrant politicization is barely a factor (Francophone Belgium. This finding is counter-intuitive because an important strand of immigrant policy research has emphasized the relationship between the politicization of immigration and restrictive immigrant citizenship rights. Our paper demonstrates that the different degrees of politicization of immigration in Flanders and Francophone Belgium cannot fully account for divergent cultural diversity policies. By insisting on the historical path dependency of the linguistic and religious cleavages in Belgium and their overlap, this paper offers an addendum to the politicization approach. The historical linguistic and religious differences of the Belgian regions clearly mediate the impact of the politicization of immigration on both sides of the linguistic border.

  15. Preventive Care Use among the Belgian Elderly Population: Does Socio-Economic Status Matter?

    Directory of Open Access Journals (Sweden)

    Sarah Hoeck

    2013-12-01

    Full Text Available Objective: To analyze the association between influenza and pneumococcus vaccination and blood cholesterol and blood sugar measurement by Belgian elderly respondents (≥65 years and socio-demographic characteristics, risk factors, health status and socio-economic status (SES. Methods: A cross-sectional study based on 4,544 non-institutionalized elderly participants of the Belgian Health Interview Surveys 2004 and 2008. Multivariate logistic regression models were constructed to examine the independent effect of socio-demographic characteristics, risk factors, health status and SES on the four preventive services. Results: After adjustment for age, sex, region, survey year, living situation, risk factors (body mass index, smoking status, physical activity and health status (self-assessed health and longstanding illness lower educated elderly were significantly less likely to report a blood cholesterol and blood sugar measurement. For instance, elderly participants with no degree or only primary education were less likely to have had a cholesterol and blood sugar measurement compared with those with higher education. Pneumococcus vaccination was not related to educational level, but lower income groups were more likely to have had a pneumococcus immunization. Influenza vaccination was not significantly related to SES. Conclusion: The results highlight the need to promote cholesterol and blood sugar measurement for lower SE groups, and pneumococcus immunization for the entire elderly population. Influenza immunization seems to be equally spread among different SE groups.

  16. The energy sources and nuclear energy - The point of view of the Belgian Catholic Church

    International Nuclear Information System (INIS)

    The problems related to the environment are reported regularly to the public by means of the newspapers, on radio and television. The story is the product of a journalistic process and in general does not bear much resemblance to the original event. The rate and type of reportage depend not only on the body of data available to the journalist but on the information sources the journalist chosen to use. The same story is reported in a positive or negative way. Finally people are overwhelmed by contradictory information and became uncertain or frightened. In order to provide the general public with objective information about nuclear energy in particular and to made a statement about the position of the Belgian Catholic Church concerning this matter, the results of the study were published in Dutch under the form of a book with the title 'The Energy Sources and Nuclear Energy - Comparative analysis and ethical thoughts written the same author. Thia paper is a short survey of the results of the study and to present the point of view of the Belgian Catholic Church in the energy debate

  17. On the role of radiologists in the Belgian PROject on CAncer of the REctum, PROCARE.

    Science.gov (United States)

    Penninckx, F; Danse, E

    2006-01-01

    Radiologists are involved at all stages of the treatment of patients with rectum cancer: in the preoperative staging, in the diagnosis of postoperative complications, in the detection of recurrent or metastatic disease during follow-up, in the monitoring of the therapeutic effect of palliative therapy. PROCARE is a Belgian national project to improve outcome in all patients with rectum cancer. Guidelines were made by a multidisciplinary workgroup and are available on the web. Decentralised implementation of guidelines is organised by the scientific and professional organisations. It is planned that a central review committee of radiologists, delegated by the Royal Belgian Society of Radiology, will survey the quality of preoperative staging. Overall quality of care will be assured by registration in a specific national database starting in 2006. Participating teams will receive annual feedback. Radiologists should provide data on cTNM staging and cCRM. Differentiation between cT2 and cT3, cN0 and cN+, and measurement of the cCRM in mm are crucial as they have a relevant impact on treatment strategy. While spiral abdominal CT is adequate for cM staging, high-resolution MRI is highly recommended and, in fact, a necessity for locoregional staging because its adequacy is superior to that of CT-scan and EUS. However, EUS is mandatory when local excision is considered, i.e. for cT1N0 lesions. PMID:16607873

  18. Occupational stress, work-home interference and burnout among Belgian veterinary practitioners

    Directory of Open Access Journals (Sweden)

    Hansez I

    2008-04-01

    Full Text Available Abstract There have been few formal studies on stress in veterinary surgeons and, in the rare studies available, stress is not examined jointly through the levels of job strain and job engagement, the sources of stress in the issue of work environment and the work-home interference. The authors' goal in this study was to analyse job engagement, job strain, burnout, work-home interference and job stress factors among 216 Belgian veterinary surgeons. Rural practice was compared to small animal and mixed activity. The mean job strain and job engagement level in veterinary surgeons was not higher than what we found in other working populations. However, 15.6% of the group were found to be suffering from high burnout. Rural practitioners had a lower level of job engagement than small animal veterinary surgeons. These small animal practitioners had a lower level of job strain than the mixed practitioners. The level of burnout did not differ significantly across the three types of activity. In comparison to other Belgian and Dutch workers, veterinary surgeons perceived more negative work-home interference. Bovine and mixed practitioners were the most concerned with this problem. The two most important sources of stress reported by bovine practitioners were relations to farmers and working time management (including emergencies and availability.

  19. Risk perception of the Belgian population. Results of the public opinion survey in 2006

    Energy Technology Data Exchange (ETDEWEB)

    Van Aeken, K.; Turcanu, C.; Bombaerts, G.; Carle, B.; Hardeman, F.

    2007-01-15

    The Belgian Nuclear Research Center SCK-CEN 2006 risk perception barometer is based on over 1000 Computer Assisted Personal Interviews, taken from persons selected to be representative for the Belgian 18+ population, and all realized in the period March 21st to April 12th 2006. Besides the classical background variables used to obtain the quota for representativity (age, language, habitat, gender and social class), we also included a series of questions assessing the sociological context and the psychological personality profile. The main topics in the survey were I) risk perception and confidence in authorities; II) acceptance of legal norms for food products; III) acceptance of countermeasures for the food chain in case of a radiological contamination and associated consumers behaviour; IV) energy; v) disposal of radioactive waste; vi) perception of the Chernobyl accident and its consequences. Some of the questions asked in 2006 are similar to those enquired in the SCK barometer of 2002, in order to study the time evolution of the risk perception associated with various issues. For the part related to acceptance of legal norms and of countermeasures for the food chain, simulated news bulletins were used in order to better reproduce the real-life context of a contamination.

  20. SCK-CEN 2006 barometer on risk perception of the Belgian population

    International Nuclear Information System (INIS)

    Starting with 2000, the expert group Society and Policy Support carries out research on various aspects of risk governance. Measuring several risk perception items at regular intervals with the Belgian population is an important part of this research. SCK-CEN has organised a first risk perception barometer in 2002 and a second one in 2006. The 2006 barometer is based on 1063 Computer Assisted Personal Interviews, with a duration of approximately 35 minutes. The large scale of the survey ensures that general trends can be detected and allows specific and detailed analysis on subgroups of the population. Besides the classical background variables used to obtain a sample representative for the Belgian 18+ population (age, language, habitat, gender and social class), several questions were included assessing the sociological context and the psychological personality profile. A series of questions on risk perception, confidence in authorities and specific nuclear topics were repeated in 2006 and constitute a fixed core, allowing comparison over time in Belgium, as well as with the results from the IRSN French barometer. In addition, a number of topics such as acceptance of legal norms and management options for radioactively contaminated milk, energy, nuclear waste and the perception of the Chernobyl accident were covered in detail in the 2006 edition of the SCK-CEN barometer

  1. Risk perception of the Belgian population. Results of the public opinion survey in 2006

    International Nuclear Information System (INIS)

    The Belgian Nuclear Research Center SCK-CEN 2006 risk perception barometer is based on over 1000 Computer Assisted Personal Interviews, taken from persons selected to be representative for the Belgian 18+ population, and all realized in the period March 21st to April 12th 2006. Besides the classical background variables used to obtain the quota for representativity (age, language, habitat, gender and social class), we also included a series of questions assessing the sociological context and the psychological personality profile. The main topics in the survey were I) risk perception and confidence in authorities; II) acceptance of legal norms for food products; III) acceptance of countermeasures for the food chain in case of a radiological contamination and associated consumers behaviour; IV) energy; v) disposal of radioactive waste; vi) perception of the Chernobyl accident and its consequences. Some of the questions asked in 2006 are similar to those enquired in the SCK barometer of 2002, in order to study the time evolution of the risk perception associated with various issues. For the part related to acceptance of legal norms and of countermeasures for the food chain, simulated news bulletins were used in order to better reproduce the real-life context of a contamination.

  2. The Belgian regulatory framework for NORM industries : test-case of a phosphate production plant

    International Nuclear Information System (INIS)

    According to the Belgian radiation protection regulatory framework, some categories of NORM industries must register to the competent Belgian radiation protection authority (FANC, Federal Agency for Nuclear Control). The facilities must provide a set of information which allows the authority to assess the radiological impact of the industrial activity on the workers, the population and the environment. If the dose exceeds or is likely to exceed 1 mSv/y, corrective measures have to be implemented. FANC has issued a methodology in order to define more precisely the data needed to evaluate the radiological impact. The methodology lists also the exposure pathways which have to be taken into account and the relevant parameters for the evaluation of the doses. The case of a phosphate production plant is discussed in more details: although the exposure of the workers in the production process as such is rather limited, the specific activity of some residues (calcium fluoride sludge) reaches around 10 kBq/kg of Ra-226. This sludge is disposed off in a specific landfill for which a program of radiological monitoring has been implemented. It includes periodic measurements of dose rate and radon concentration on the landfill. (author)

  3. Bone mineral density, body mass index and cigarette smoking among Iranian women: implications for prevention

    Directory of Open Access Journals (Sweden)

    Nguyen Nguyen D

    2005-06-01

    Full Text Available Abstract Background While risk factors of osteoporosis in Western populations have been extensively documented, such a profile has not been well studied in Caucasians of non-European origin. This study was designed to estimate the modifiable distribution and determinants of bone mineral density (BMD among Iranian women in Australia. Methods Ninety women aged 35 years and older completed a questionnaire on socio-demographic and lifestyle factors. BMD was measured at the lumbar spine (LS and femoral neck (FN using DXA (GE Lunar, WI, USA, and was expressed in g/cm2 as well as T-score. Results In multiple regression analysis, advancing age, lower body mass index (BMI, and smoking were independently associated with LS and FN BMD, with the 3 factors collectively accounting for 30% and 38% variance of LS and FN BMD, respectively. LS and FN BMD in smokers was 8% lower than that in non-smokers. Further analysis of interaction between BMI and smoking revealed that the effect of smoking was only observed in the obese group (p = 0.029 for LSBMD and p = 0.007 for FNBMD, but not in the overweight and normal groups. Using T-scores from two bone sites the prevalence of osteoporosis (T-scores ≤ -2.5 was 3.8% and 26.3% in pre-and post-menopausal women, respectively. Among current smokers, the prevalence was higher (31.3% than that among ex-smokers (28.6% and non-smokers (7.5%. Conclusion These data, for the first time, indicate that apart from advancing age and lower body mass index, cigarette smoking is an important modifiable determinant of bone mineral density in these Caucasians of non-European origin.

  4. Vaginal Fibroblastic Cells from Women with Pelvic Organ Prolapse Produce Matrices with Increased Stiffness and Collagen Content

    Science.gov (United States)

    Ruiz-Zapata, Alejandra M.; Kerkhof, Manon H.; Ghazanfari, Samaneh; Zandieh-Doulabi, Behrouz; Stoop, Reinout; Smit, Theo H.; Helder, Marco N.

    2016-01-01

    Pelvic organ prolapse (POP) is characterised by the weakening of the pelvic floor support tissues, and often by subsequent prolapse of the bladder outside the body, i.e. cystocele. The bladder is kept in place by the anterior vaginal wall which consists of a dense extracellular matrix rich in collagen content that is maintained and remodelled by fibroblastic cells, i.e. fibroblasts and myofibroblasts. Since altered matrix production influences tissue quality, and myofibroblasts are involved in normal and pathological soft tissue repair processes, we evaluated matrix production of cells derived from pre- and post-menopausal POP and non-POP control anterior vaginal wall tissues. Results showed that cells from postmenopausal POP women deposited matrices with high percentage of collagen fibres with less anisotropic orientation and increased stiffness than those produced by controls. There was a transient increase in myofibroblastic phenotype that was lost after the peak of tissue remodelling. In conclusion, affected fibroblasts from postmenopausal prolapsed tissues produced altered matrices in vitro compared to controls. Such aberrant altered matrix production does not appear to be a consequence of abnormal phenotypical changes towards the myofibroblastic lineage. PMID:26965792

  5. De communicatiefunctie in Belgische organisaties: Hoe excellent is deze ingevuld? [Communications functions in Belgian organizations: How excellently are they implemented?

    NARCIS (Netherlands)

    Gorp, B. van; Pauwels, L.M.A.

    2009-01-01

    This study presents data, which were obtained by a web survey (n = 750), concerning the position of communications in the hierarchical structure of Belgian organizations with at least 50 employees. Results show that 43 percent of the organizations in the sample have an integrated communications depa

  6. The Belgian Minister of Economy, Energy, Foreign Trade and Science Policy, Marc Verwilghen, with CERN's Director-General, Robert Aymar.

    CERN Multimedia

    Michel Blanc

    2005-01-01

    Marc Verwilghen, Belgian Minister of Economy, Energy, Foreign Trade and Science Policy, came to CERN on 8 April 2005, where he visited the CMS assembly hall and underground cavern, as well as the hall where the LHC superconducting magnets are being tested.

  7. Work related neck and upper limb symptoms (RSI) : high risk occupations and risk factors in the Belgian working population

    NARCIS (Netherlands)

    Blatter, B.M.; Bongers, P.M.; Witte, H. de

    1999-01-01

    In this study on prevalence and risk factors for work related neck or upper limb symptoms in the Belgian working population, the researchers have found an overall prevalence of work and upper limb symptoms occurring in the past 12 months of 39%. High risk occupations for neck and shoulder symptoms w

  8. Modeling the effect of levothyroxine therapy on bone mass density in postmenopausal women: a different approach leads to new inference

    Directory of Open Access Journals (Sweden)

    Tavangar Seyed

    2007-06-01

    Full Text Available Abstract Background The diagnosis, treatment and prevention of osteoporosis is a national health emergency. Osteoporosis quietly progresses without symptoms until late stage complications occur. Older patients are more commonly at risk of fractures due to osteoporosis. The fracture risk increases when suppressive doses of levothyroxine are administered especially in postmenopausal women. The question is; "When should bone mass density be tested in postmenopausal women after the initiation of suppressive levothyroxine therapy?". Standard guidelines for the prevention of osteoporosis suggest that follow-up be done in 1 to 2 years. We were interested in predicting the level of bone mass density in postmenopausal women after the initiation of suppressive levothyroxine therapy with a novel approach. Methods The study used data from the literature on the influence of exogenous thyroid hormones on bone mass density. Four cubic polynomial equations were obtained by curve fitting for Ward's triangle, trochanter, spine and femoral neck. The behaviors of the models were investigated by statistical and mathematical analyses. Results There are four points of inflexion on the graphs of the first derivatives of the equations with respect to time at about 6, 5, 7 and 5 months. In other words, there is a maximum speed of bone loss around the 6th month after the start of suppressive L-thyroxine therapy in post-menopausal women. Conclusion It seems reasonable to check bone mass density at the 6th month of therapy. More research is needed to explain the cause and to confirm the clinical application of this phenomenon for osteoporosis, but such an approach can be used as a guide to future experimentation. The investigation of change over time may lead to more sophisticated decision making in a wide variety of clinical problems.

  9. A federal audit of the Belgian radiotherapy departments in breast cancer treatment

    International Nuclear Information System (INIS)

    Background: The Belgian Federal College of Radiotherapy carried out an external audit of breast cancer patient documentation in the 26 Belgian radiotherapy centres. The objective was to assess compliance with the recommendations regarding minimal requirements for documentation of radiotherapy prescription and administration. All centres volunteered to take part in this audit. Methods: Two experienced radiation oncologists site-visited the departments over a 6 month period (Sept. 2003-Feb. 2004), with a list of items to be verified, including details on the surgery, the pathological report, details on systemic treatments, details on the radiotherapy prescription (and consistency with therapeutic guidelines) and delay surgery/radiotherapy. Findings: Three hundred and eighty-nine patients files were reviewed, for a total of 399 breast cancers (10 patients with bilateral cancer). Mean age was 57.8 y (range 29-96). Breast conservative surgery (BCS) was used in 71%; radical mastectomy in 29%. A complete pathological report was present in all files but 2 (99.5% conformity). 5.2% were treated for DCIS, 61.6% for pT1, 28.2% for pT2 and 5% for pT3-4. Data regarding resection margins were specified to be free in 76.2%, tangential in 12% (within 2 mm) and positive for DCIS in 3.8% or invasive cancer in 1.5% (no information, on margins in 6.5%). The pT stage was always specified, and consistent with the macroscopic and microscopic findings. Hormonal receptors were routinely assessed (94.7%), as well as Her2neu (87.4%). Axillary surgery was carried out in 92%, either by sentinel node biopsy or by complete clearance, in which case the median number of nodes analysed was 12 for all centres together (7-17). All radiotherapy prescriptions were in line with evidence-based standards of therapy (i.e., irradiation of breast after BCS or after mamectomy (in case of pN+), but one. The mean delay between surgery and radiotherapy was 5.5 weeks (SD 11days). Conclusion: There was a high

  10. RISCOM Applied to the Belgian Partnership Model: More and Deeper Levels

    Energy Technology Data Exchange (ETDEWEB)

    Bombaerts, Gunter; Bovy, Michel; Laes, Erik [SCKCEN, Mol (Belgium). PISA

    2006-09-15

    Technology participation is not a new concept. It has been applied in different settings in different countries. In this article, we report a comparing analysis of the RISCOM model in Sweden and the Belgian partnership model for low and intermediate short-lived nuclear waste. After a brief description of the partnerships and the RISCOM model, we apply the latter to the first and come to recommendations for the partnership model. The strength of the partnership approach is at the community level. In one of the villages, up to one percent of the population was motivated to discuss at least once a month for four years the nuts and bolts of the repository concept. The stress on the community level and the lack of a guardian includes a weakness as well. First of all, if communities come into competition, the inter-community discussions can start resembling local politics and can become less transparent. Local actors are concerned actors but actors at the national level are concerned as well. The local decisions influence how the waste will be transported. The local decisions also determine an extra cost of electricity. We therefore recommend a broad (in terms of territory) public debate on the participation experiments preceding and concluding the local participation process in which this local process maintains an important position. The conclusions of our comparative analysis are: (1) The guardian of the process at the national level is missing. Since the Belgian nuclear regulator plays a controlling role after the process, we recommend a technology assessment institute at the federal level. (2) We state that stretching in the partnership model can happen more profoundly and recommend a 'counter institute' at the European level. The role of non-participative actors should be valued. (3) Recursion levels can be taken as a point of departure for discussion about the problem framing. If people accept them, there is no problem. If people clearly mention issues

  11. RISCOM Applied to the Belgian Partnership Model: More and Deeper Levels

    International Nuclear Information System (INIS)

    Technology participation is not a new concept. It has been applied in different settings in different countries. In this article, we report a comparing analysis of the RISCOM model in Sweden and the Belgian partnership model for low and intermediate short-lived nuclear waste. After a brief description of the partnerships and the RISCOM model, we apply the latter to the first and come to recommendations for the partnership model. The strength of the partnership approach is at the community level. In one of the villages, up to one percent of the population was motivated to discuss at least once a month for four years the nuts and bolts of the repository concept. The stress on the community level and the lack of a guardian includes a weakness as well. First of all, if communities come into competition, the inter-community discussions can start resembling local politics and can become less transparent. Local actors are concerned actors but actors at the national level are concerned as well. The local decisions influence how the waste will be transported. The local decisions also determine an extra cost of electricity. We therefore recommend a broad (in terms of territory) public debate on the participation experiments preceding and concluding the local participation process in which this local process maintains an important position. The conclusions of our comparative analysis are: (1) The guardian of the process at the national level is missing. Since the Belgian nuclear regulator plays a controlling role after the process, we recommend a technology assessment institute at the federal level. (2) We state that stretching in the partnership model can happen more profoundly and recommend a 'counter institute' at the European level. The role of non-participative actors should be valued. (3) Recursion levels can be taken as a point of departure for discussion about the problem framing. If people accept them, there is no problem. If people clearly mention issues that are

  12. Body fatness and breast cancer risk in women of African ancestry

    International Nuclear Information System (INIS)

    Obesity has been shown to be inversely associated with breast cancer risk in premenopausal women, while increasing risk in postmenopausal women. However, the current evidence is largely based on studies in Caucasian populations. Associations in women of African ancestry (AA), who have a higher prevalence of obesity, have been evaluated in few studies and results suggest different effects. We evaluated the impact of body size, body fat distribution, and body composition on breast cancer risk among AA women (978 cases and 958 controls) participating in the Women’s Circle of Health Study, a multi-site case–control study in New York City (NYC) and New Jersey (NJ). Cases were newly diagnosed with histologically confirmed ductal carcinoma in situ or invasive breast cancer, age 20–75 yrs. In NYC, cases were recruited through hospitals with the largest referral patterns for AA women and controls through random digit dialing (RDD). In NJ, cases were identified in seven counties in NJ thorough the NJ State Cancer Registry, and controls through RDD and community-based recruitment. During in-person interviews, questionnaires were administered and detailed anthropometric measurements were obtained. Body composition was assessed by bioelectrical impedance analysis. BMI did not have a major impact on pre- or post-menopausal breast cancer, but was significantly associated with reduced risk of ER-/PR- tumors among postmenopausal women (OR: 0.37; 95% CI: 0.15-0.96 for BMI > 30 vs. BMI < 25). Furthermore, increased premenopausal breast cancer risk was found for higher waist and hip circumferences after adjusting for BMI, with ORs of 2.25 (95% CI: 1.07-4.74) and 2.91 (95% CI: 1.39-6.10), respectively, comparing the highest vs. lowest quartile. While ORs for higher fat mass and percent body fat among postmenopausal women were above one, confidence intervals included the null value. Our study suggests that in AA women BMI is generally unrelated to breast cancer. However, higher

  13. Women's Health

    Science.gov (United States)

    Women have unique health issues. And some of the health issues that affect both men and women can affect women differently. Unique issues ... and men also have many of the same health problems. But these problems can affect women differently. ...

  14. Genetic parameters and estimated breeding values of insect bite hypersensitivity in Belgian Warmblood horses.

    Science.gov (United States)

    Peeters, Liesbet M; Janssens, Steven; Brebels, Machteld; Buys, Nadine

    2015-12-01

    Genetic factors involved in susceptibility to insect bite hypersensitivity (IBH) in Belgian Warmblood horses (BWP) were investigated. Data relating to 3409 horses were collected using a questionnaire, administered to owners during sport competitions, BWP breeding days, breeder visits and after phone calls. Horses were classified as IBH-affected or unaffected, based on two 'disease classifiers': a lifetime record, based on owner information (life_status) and another based on whether or not the horse was showing clinical signs at the time of questioning (clin_status). IBH prevalence was 10% based on life_status, and 6.2% based on clin_status. The heritabilities estimated using threshold animal models varied from 0.65 to 0.78 on the underlying scale (0.18-0.26 on the observed scale). These research findings indicate that susceptibility to IBH is a heritable trait in BWP. PMID:26586216

  15. Chemical analyses of dredged spoil disposal sites at the Belgian part of the North Sea.

    Science.gov (United States)

    De Witte, Bavo; Ruttens, Ann; Ampe, Bart; Waegeneers, Nadia; Gauquie, Johanna; Devriese, Lisa; Cooreman, Kris; Parmentier, Koen

    2016-08-01

    The chemical status of five dredged spoil disposal sites in the Belgian Part of the North Sea is evaluated. A linear mixed-effect model was applied to PCB, PAH and heavy metal data from 2005 to 2014. No decrease in PCB concentrations was found, with even an increase at two disposal sites. Hg/AL ratios increased with 62% at one disposal site (BR&WS2) from 2005 to 2006 to 2013-2014. Cu and Zn concentrations increased at two disposal sites. Additional harbour sampling suggests that the latter is possibly linked to antifouling paints. Based on OSPAR environmental assessment criteria, the current chemical status of the sites suggests no chronic effect of dredged spoil disposal. However, increasing time trend data for PCB, Hg, Cu and Zn demonstrate the importance of monitoring to identify adverse trends. PMID:27176939

  16. COMPARISON OF TWO METHODS OF OPERATING THEATRE PLANNING: APPLICATION IN BELGIAN HOSPITAL

    Institute of Scientific and Technical Information of China (English)

    Sondes CHAABANE; Nadine MESKENS; Alain GUINET; Marius LAURENT

    2008-01-01

    Operating Theatre is the centre of the hospital management's efforts. It constitutes the most expensive sector with more than 10% of the intended operating budget of the hospital. To reduce the costs while maintaining a good quality of care, one of the solutions is to improve the existent planning and scheduling methods by improving the services and surgical specialty coordination or finding the best estimation of surgical case durations. The other solution is to construct an effective surgical case plan and schedule. The operating theatre planning and scheduling is the two important steps, which aim to make a surgical case programming with an objective of obtaining a realizable and efficient surgical case schedule. This paper focuses on the first step, the operating theatre planning problem. Two planning methods are introduced and compared. Real data of a Belgian university hospital "Tivoli" are used for the experiments.

  17. Engineering for Operation of a Future Belgian Deep Geological Repository for ILW and HLW - 12379

    International Nuclear Information System (INIS)

    In Belgium, an advanced conceptual design is being elaborated for deep geologic disposal of high level waste (HLW) and for low and intermediate level waste (LILW) not amenable for surface disposal. The concept is based on a shielded steel and concrete container for disposal of HLW, i.e., the Super-container. LILW will be disposed of in separately designed concrete caissons. The reference host rock is the Boom Clay, a poorly indurated clay formation in northeastern Belgium. Investigations into the potential host rock are conducted at the HADES underground research laboratory in Mol, Belgium. In 2009 the Belgian Agency for Management of Radioactive Waste and Enriched Fissile Materials (ONDRAF/NIRAS) initiated a four year research project aimed at confirming the fundamental feasibility of building and operating a repository. The goal of the program is to demonstrate at a detailed conceptual level that the proposed geologic disposal system can be safely constructed, operated, and progressively closed. Part of the broader research efforts being conducted includes evaluations optimization of the waste transportation shaft, subsurface transportation system, ventilation system, and evaluation of backfilling and sealing concepts for the repository design. The potential for implementation of a waste retrieval strategy encompassing the first 100 years after emplacement is also considered. In the framework of a four year research program aimed at confirming the fundamental feasibility of building and operating a repository in poorly indurated clay design studies have been underway to optimize the waste transportation shaft, subsurface transportation system, and ventilation system. Additionally backfilling and sealing concepts proposed for the potential repository have been reviewed in conjunction with impacts related to the potential future inclusion of a retrievability requirement in governing regulations. The main engineering challenges in the Belgian repository concept are

  18. Brief report: Citizenship concepts among adolescents. Evidence from a survey among Belgian 16-year olds.

    Science.gov (United States)

    Dejaeghere, Yves; Hooghe, Marc

    2009-06-01

    In this research note we investigate the occurrence of citizenship concepts among adolescents in Belgium. The analysis is based on the Belgian Youth Survey (2006), which is a representative survey among 6330 16-year olds in the country. Citizenship concepts were shown to be multi-dimensional, with distinct factors for conventional or electoral participation and civic engagement. A third, weaker factor could be distinguished covering obedience to the law. This structure is largely in line with earlier comparative analysis. An exploratory analysis suggests that these factors have different outcomes on actual or intended political participation behavior of adolescents. We discuss the relevance of these findings with regard to the current debates on civic education and civic engagement among younger age cohorts. PMID:19264354

  19. Qualification of non-destructive examination for belgian nuclear reactor pressure vessel inspection

    Energy Technology Data Exchange (ETDEWEB)

    Couplet, D. [TRACTEBEL, Brussels (Belgium); Francoise, T. [Intercontrole, 94 - Rungis (France)

    2001-07-01

    In Service Inspection (ISI) participates to the assessment of Nuclear Reactor Pressure Vessel Integrity. The performance of Non Destructive Examination (NDE) techniques must be demonstrated according to predefined objectives. The qualification process is essential to trust the reliability of the information provided by NDE. In Belgian Nuclear Power Plants, the qualification was conducted through a collaboration between the vendor and a technical group from the Electricity Utility. The important facts of this qualification will be presented: - the detailed definition of the inspection and qualifications objectives, based on a combination of the ASME code and the European Methodology for Qualification; - the systematic verification of the NDE performance and limitations, for each ISI objective, through an adequate combination of tests on blocks and technical justification; - the continuous improvement of the NDE procedure; - the feedback and the lessons learnt from site experience; - the necessary multi-disciplinary approach (NDE, degradation mechanisms, structural integrity)

  20. Congomania in Academia. Recent Historical Research on the Belgian Colonial Past

    Directory of Open Access Journals (Sweden)

    S.E. Kiangu

    2011-01-01

    Full Text Available The Congo has recently been the subject of much academic research. This article discusses the major trends and developments. It primarily focuses on the Congo crisis of 1960, which was commemorated in 2010 and has been inquired into by many historians, including American, British and Russian ones. A comparison of their conclusions reveals that Flanders has largely come to terms with its colonial past, but that the French-speaking community has a more problematic memory. Belgian academia, by contrast, has left the old controversies about Leopold II and Lumumba behind and embarked on the path of new imperial history. It approaches the Congolese past from new angles and with new paradigms, such as reciprocity, science, exhibition, representation, etc. Congolese academia suffers from the economic problems of the country, but has managed to produce a number of studies, focusing mainly on regions, religion, and resistance. Strikingly, Congolese historians have little criticism of the colonial era.

  1. 1997 Scientific Report[1997 Scientific Report of the Belgian Nuclear Research Centre

    Energy Technology Data Exchange (ETDEWEB)

    Govaerts, P.

    1998-07-01

    The 1997 Scientific Report of the Belgian Nuclear Research Centre SCK-CEN describes progress achieved in nuclear safety, radioactive waste management, radiation protection and safeguards. In the field of nuclear research, the main projects concern the behaviour of high-burnup and MOX fuel, the embrittlement of reactor pressure vessels, the irradiation-assisted stress corrosion cracking of reactor internals, and irradiation effects on materials of fusion reactors. In the field of radioactive waste management, progress in the following domains is reported: the disposal of high-level radioactive waste and spent fuel in a clay formation, the decommissioning of nuclear installations, the study of alternative waste-processing techniques. For radiation protection and safeguards, the main activities reported on are in the field of site and environmental restoration, emergency planning and response and scientific support to national and international programmes.

  2. Radiological optimization[1997 Scientific Report of the Belgian Nuclear Research Centre

    Energy Technology Data Exchange (ETDEWEB)

    Zeevaert, T.

    1998-07-01

    Radiological optimization is one of the basic principles in each radiation-protection system and it is a basic requirement in the safety standards for radiation protection in the European Communities. The objectives of the research, performed in this field at the Belgian Nuclear Research Centre SCK-CEN, are: (1) to implement the ALARA principles in activities with radiological consequences; (2) to develop methodologies for optimization techniques in decision-aiding; (3) to optimize radiological assessment models by validation and intercomparison; (4) to improve methods to assess in real time the radiological hazards in the environment in case of an accident; (5) to develop methods and programmes to assist decision-makers during a nuclear emergency; (6) to support the policy of radioactive waste management authorities in the field of radiation protection; (7) to investigate existing software programmes in the domain of multi criteria analysis. The main achievements for 1997 are given.

  3. Sustainability of Global and Local Food Value Chains: An Empirical Comparison of Peruvian and Belgian Asparagus

    Directory of Open Access Journals (Sweden)

    Jana Schwarz

    2016-04-01

    Full Text Available The sustainability of food value chains is an increasing concern for consumers, food companies and policy-makers. Global food chains are often perceived to be less sustainable than local food chains. Yet, thorough food chain analyses and comparisons of different food chains across sustainability dimensions are rare. In this article we analyze the local Belgian and global Peruvian asparagus value chains and explore their sustainability performance. A range of indicators linked to environmental, economic and social impacts is calculated to analyze the contribution of the supply chains to economic development, resource use, labor relations, distribution of added value and governance issues. Our findings suggest that none of the two supply chains performs invariably better and that there are trade-offs among and between sustainability dimensions. Whereas the global chain uses water and other inputs more intensively and generates more employment per unit of land and higher yields, the local chain generates more revenue per unit of land.

  4. Health effects[1997 Scientific Report of the Belgian Nuclear Research Centre

    Energy Technology Data Exchange (ETDEWEB)

    Mahieu, L.

    1998-07-01

    The objectives of the research in the field of epidemiology , performed at the Belgian Nuclear Research Centre SCK-CEN are (1) to study cancer mortality and morbidity in nuclear workers in Belgium; (2) to document the feasibility of retrospective cohort studies in Belgium; (3) to participate in the IARC study. For radiobiology, the main objectives are: (1) to elucidate the mechanisms of the effects of ionizing radiation on the mammalian embryo during the early phase of its development, (2) to assess the genetic risks of maternal exposure to ionizing radiation, (3) to elucidate the mechanisms by which damage to the brain and mental retardation are caused in man after prenatal irradiation. The main achievements in these domains for 1997 are presented.

  5. Safety culture in a Belgian nuclear research centre from a social science point of view

    International Nuclear Information System (INIS)

    This paper is the result of a reflection within the framework of a Ph.D. research at SCK-CEN (Belgian Nuclear Research Centre) in collaboration with the University of Liege. The starting point of the work was the 'safety culture' model presented in the IAEA report 75-INSAG-4. This model is applied to the working organization of the SCK-CEN, also considering the safety culture as an open concept given its multi dimensionality. The methodology is based on three methods: observations, focus groups and interviews. The fieldwork was limited to two main installations: a research reactor, and a dismantling site. The preliminary findings are based on the data resulting from 4 Focus Groups. The most prominent components of a safety culture and the multiplicity of safety cultures in a large organization such as SCK-CEN will be discussed. (author)

  6. Behaviour of the steam generators in the Belgian nuclear power plants

    International Nuclear Information System (INIS)

    After a brief review of the degradations occurring on tubes of Inconel 600 in steam generators of PWR power stations emphasis is put on the conditioning of the secondary water and more particularly on the condensate treatment in the units of Doel which work on heavily polluted brackish water. The important role of non-destructive testing and eddy-current testing is also pointed out, method developed by Laborelec. The operational experience shows that Belgian stations are nearly not concerned by the degradations mostly found in power stations in other countries which shows the efficiency of the conditioning of the secondary water. On the other hand, other problems have occurred, resulting from: damage caused by foreign objects; fouling of tube before commissioning, cracking of bends and at the limit of the dudgeoning and leaking plugs. (AF)

  7. The Belgian coal tips: geomorphic and pedogenetic research with community service and educational aspects

    Science.gov (United States)

    Nyssen, Jan; Vermeersch, Dominiek; Diependaele, Stijn; van Ranst, Eric; Derycke, Anja; Corexenos, Pavlos; Palmers, Jo; Poesen, Jean

    2010-05-01

    Coal tips are composed of various materials, essentially sterile rock but also waste such as mine wood, scrap metal as well as scoria from surface facilities. Rocks composing Belgian coal tips belong to the Westfalian and Namurian (approx. 320 Ma) and include psammites, schists and coal residues. Currently, these coal tips are increasingly regarded as socio-cultural heritage. Worldwide, several studies have focused on the factors controlling the magnitude of geomorphic processes, such as nature of slope material, vegetation type and cover, the role of self-ignition and combustion, time and slope gradient. In the international literature, research gaps concern particular processes, such as causes and consequences of the widespread tree toppling and root throw, rock fragment movement at the surface, or gully control by check dams. Especially spatially distributed erosion rates by the various processes active on coal tips, neither sediment budgets seem ever to have been established. The same holds for regional (subcontinental) variability in slope processes on coal tips. The many Belgian coal tips that have not been levelled provide a unique opportunity for geomorphological and pedogenetical studies, which have so far demonstrated the existence of: - correlations between the intensity of observed geomorphic processes and a broad range of bio-physical explanatory factors; - strong and reciprocal influences between the vegetation of coal tips and the morphology of the colonised slopes; - absence of strong relations between gully activity and slope angle, resulting from the narrow range of slope gradients on coal tips; - possibilities to locate landslide risk zones through combined use of Digital Elevation Models and thermographic imagery; - presence of neoformed minerals on burning/burned coal tips, which impact the soil forming processes as well as soil quality.

  8. Average daily nitrate and nitrite intake in the Belgian population older than 15 years.

    Science.gov (United States)

    Temme, E H M; Vandevijvere, S; Vinkx, C; Huybrechts, I; Goeyens, L; Van Oyen, H

    2011-09-01

    The aim of this study was to assess the dietary intake of nitrate and nitrite in Belgium. The nitrate content of processed vegetables, cheeses and meat products was analysed. These data were completed by data from non-targeted official control and from the literature. In addition, the nitrite content of meat products was measured. Concentration data for nitrate and nitrite were linked to food consumption data of the Belgian Food Consumption Survey. This study included 3245 respondents, aged 15 years and older. Food intakes were estimated by a repeated 24-h recall using EPIC-SOFT. Only respondents with two completed 24-h recalls (n=3083) were included in the analysis. For the intake assessment, average concentration data and individual consumption data were combined. Usual intake of nitrate/nitrite was calculated using the Nusser method. The mean usual daily intake of nitrate was 1.38 mg kg(-1) bodyweight (bw) day(-1) and the usual daily intake at the 97.5 percentile was 2.76 mg kg(-1) bw day(-1). Exposure of the Belgian population to nitrate at a mean intake corresponded to 38% of the ADI (while 76% at the 97.5 percentile). For the average consumer, half of the intake was derived from vegetables (especially lettuce) and 20% from water and water-based drinks. The average daily intake of nitrate and nitrite from cheese and meat products was low (0.2% and 6% of the ADI at average intake, respectively). Scenario analyses with a higher consumption of vegetables or a higher nitrate concentration in tap water showed a significant higher intake of nitrate. Whether this is beneficial or harmful must be further assessed. PMID:21728895

  9. Risk assessment for furan contamination through the food chain in Belgian children.

    Science.gov (United States)

    Scholl, Georges; Huybrechts, Inge; Humblet, Marie-France; Scippo, Marie-Louise; De Pauw, Edwin; Eppe, Gauthier; Saegerman, Claude

    2012-08-01

    Young, old, pregnant and immuno-compromised persons are of great concern for risk assessors as they represent the sub-populations most at risk. The present paper focuses on risk assessment linked to furan exposure in children. Only the Belgian population was considered because individual contamination and consumption data that are required for accurate risk assessment were available for Belgian children only. Two risk assessment approaches, the so-called deterministic and probabilistic, were applied and the results were compared for the estimation of daily intake. A significant difference between the average Estimated Daily Intake (EDI) was underlined between the deterministic (419 ng kg⁻¹ body weight (bw) day⁻¹) and the probabilistic (583 ng kg⁻¹ bw day⁻¹) approaches, which results from the mathematical treatment of the null consumption and contamination data. The risk was characterised by two ways: (1) the classical approach by comparison of the EDI to a reference dose (RfD(chronic-oral)) and (2) the most recent approach, namely the Margin of Exposure (MoE) approach. Both reached similar conclusions: the risk level is not of a major concern, but is neither negligible. In the first approach, only 2.7 or 6.6% (respectively in the deterministic and in the probabilistic way) of the studied population presented an EDI above the RfD(chronic-oral). In the second approach, the percentage of children displaying a MoE above 10,000 and below 100 is 3-0% and 20-0.01% in the deterministic and probabilistic modes, respectively. In addition, children were compared to adults and significant differences between the contamination patterns were highlighted. While major contamination was linked to coffee consumption in adults (55%), no item predominantly contributed to the contamination in children. The most important were soups (19%), dairy products (17%), pasta and rice (11%), fruit and potatoes (9% each). PMID:22632631

  10. Salmonella surveillance and control at post-harvest in the Belgian pork meat chain.

    Science.gov (United States)

    Delhalle, L; Saegerman, C; Farnir, F; Korsak, N; Maes, D; Messens, W; De Sadeleer, L; De Zutter, L; Daube, G

    2009-05-01

    Salmonella remains the primary cause of reported bacterial food borne disease outbreaks in Belgium. Pork and pork products are recognized as one of the major sources of human salmonellosis. In contrast with the primary production and slaughterhouse phases of the pork meat production chain, only a few studies have focussed on the post-harvest stages. The goal of this study was to evaluate Salmonella and Escherichia coli contamination at the Belgian post-harvest stages. E. coli counts were estimated in order to evaluate the levels of faecal contamination. The results of bacteriological analysis from seven cutting plants, four meat-mincing plants and the four largest Belgian retailers were collected from official and self-monitoring controls. The prevalence of Salmonella in the cutting plants and meat-mincing plants ranged from 0% to 50%. The most frequently isolated serotype was Salmonella typhimurium. The prevalence in minced meat at retail level ranged from 0.3% to 4.3%. The levels of Salmonella contamination estimated from semi-quantitative analysis of data relating to carcasses, cuts of meat and minced meat were equal to -3.40+/-2.04 log CFU/cm(2), -2.64+/-1.76 log CFU/g and -2.35+/-1.09 log CFU/g, respectively. The E. coli results in meat cuts and minced meat ranged from 0.21+/-0.50 to 1.23+/-0.89 log CFU/g and from 1.33+/-0.58 to 2.78+/-0.43 log CFU/g, respectively. The results showed that faecal contamination still needs to be reduced, especially in specific individual plants. PMID:19269567

  11. Pesticide exposure of two age groups of women and its relationship with their diet

    International Nuclear Information System (INIS)

    The widespread presence of organochlorine (OC) pesticides in human samples may be explained by the environmental exposure of the population. Foods are considered a constant source of exposure, despite compliance with maximum permitted residue levels. This study aimed to examine the relationship between nutritional habits of women in Southeast Spain and their serum concentrations of OCs. A semi-quantitative questionnaire was used to estimate the frequency of consumption of foods by two age groups of women, pre-menopausal (Pre-M) and post-menopausal (Post-M), and their serum pesticide levels were measured by gas chromatography (GC) with electron capture detector and confirmed by GC and mass spectrometry. The Pre-M group showed significantly higher serum concentrations of all OCs studied with the exception of DDE. The groups significantly differed in consumption of all food groups with the exception of fruit. In the Pre-M group, the mean serum p,p-DDT concentration was significantly associated with milk/yoghurt (p < 0.045) and red meat (p < 0.023), serum o,p-DDT with red meat (p < 0.049), serum aldrin with eggs (p < 0.038) and poultry (p < 0.024), and serum DDE with eggs (p < 0.025). In the Post-M group, serum lindane was associated with fresh and cured cheese (p < 0.001), red meat (p < 0.001) and white and oily fish (p < 0.001), and both serum DDE and dieldrin were associated with fresh cheese, cured cheese, red meat, and white and oily fish (p < 0.001). These results confirm foods as a source of human exposure to persistent organic molecules. Consideration should be given to the reduction of permitted residue levels to minimize this threat to human and animal health

  12. Risk factors for osteoporosis in urban Iranian postmenopausal women (A center based study

    Directory of Open Access Journals (Sweden)

    Afsane Keramat

    2007-01-01

    Full Text Available Introduction: Osteoporosis is recognized as a major healthcare problem in elders. Data on prevalence and risk factors of osteoporosis in developing countries is sparse. In this study we aim to define the risk factors of osteoporosis in a selected group of postmenopausal women in Tehran. Methods: This is a case-control, interview based study that was conducted in a popular public hospital (Shariati in Tehran during period 2002-2003. The sample sizes included 272 post menopausal women (136 case and 136 controls in the same age group. The case group were identified as osteoporotic patients based on WHO definition in spine and/or total femoral region interest using DEXA method and Lunar DPX machine. A self made questionnaire was used for data collection. It included some information on demographic, obstetrical and menstrual factors, medical and drug history, nutritional status, physical activity and life style. Risk factors for osteoporosis were calculated by adjusted odds ratios using multiple logistic regressions. Results: The significant (P 5 years (2.4, Parity >3, lactation >3 years, steroid therapy (3.6, Bone and joint disorders (2.34 teeth problems (2.30, education < 12 schooling yrs (2.6 and red meat consumption ≥ 4 times/w (2.1.Regular consumption of milk ≥ 3/w (0.4, cheese ≥ 30g/d (0.5, chicken (0.4, fish (0.3 and honey (0.42 appeared to be significant protective factors. Calcium supplementation (0.3, regular walking (0.4 and sunshine exposure (0.4 also reduced the risk significantly. Conclusion: Osteoporosis, in this study, appears to be associated with several risk factors. The association of environmental factors like diet, exercise and sunshine exposure with osteoporosis indicates need of more studies in this area and also the direction for elders, health strategies for osteoporosis prevention in Iran.

  13. A Positive Pregnancy Test in the Post-Menopausal Psychiatric Patient—: What to Think?

    OpenAIRE

    Bashir, Imad; Ihenetu, Kenneth; Miller, James J.; Gim, Min-Hye; Lippmann, Steven

    2006-01-01

    Assaying the serum β-hCG is the pregnancy test employed to verify an early pregnancy. It becomes positive at approximately 10 days after conception. Knowing whether or not a patient is pregnant is critical to avoid exposure to medications or procedures that might be teratogenic. Psychiatric patients are sometimes suboptimal historians, so such β-hCG testing is especially worthwhile to assure recognition of an active, early-stage pregnancy.

  14. Benign Ovarian Dermoid Cyst Complicated with Infection in Post Menopausal Woman: An Unusual Case

    Directory of Open Access Journals (Sweden)

    M. Hasanzadeh Mofrad

    2009-10-01

    Full Text Available Introduction: Mature teratoma is the most common germ cell tumor(and the most common tumor of the ovary,composing more than 20% of all ovarian neoplasms .Super infection of dermoid ovarian cyst is very rare.Case Report: A 72 year-old woman was admitted to the gynecological outpatient clinic because of lower abdominal pain and fever. Gynecological examination and ultrasonography revealed a heterogeneous cystic mass in the right ovary. Abdominopelvic CT scan revealed a right ovarian mass (15×15 cm thought to be a dermoid cyst. Right adnexectomy was performed. The pathological evaluation suggested infected benign ovarian dermoid.Conclusion: They are the most common ovarian neoplasm found in adolescence and during pregnancy. Mature cystic teratoma may be complicated by torsion, rupture, and malignant change infection of a mature teratoma is a relatively uncommon event. However, based on our case and other cases, superinfection with abscess formation should be considered in the differential diagnosis whenever a patient with a documented pelvic mass and fever refers to gynecologists.

  15. Effect of vaginal estrogen on post menopausal mood & sleep disturbance/ and sexual satisfaction

    OpenAIRE

    Eftekhar T; Akhoondzadeh S; Ghanbari Z; Iranshahr R; Haghollahi F

    2009-01-01

    "n Normal 0 false false false EN-GB X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-fon...

  16. Relationships between Menopausal and Mood Symptoms and EEG Sleep Measures in a Multi-ethnic Sample of Middle-Aged Women: The SWAN Sleep Study

    Science.gov (United States)

    Kravitz, Howard M.; Avery, Elizabeth; Sowers, MaryFran; Bromberger, Joyce T.; Owens, Jane F.; Matthews, Karen A.; Hall, Martica; Zheng, Huiyong; Gold, Ellen B.; Buysse, Daniel J.

    2011-01-01

    Study Objectives: Examine associations of vasomotor and mood symptoms with visually scored and computer-generated measures of EEG sleep. Design: Cross-sectional analysis. Setting: Community-based in-home polysomnography (PSG). Participants: 343 African American, Caucasian, and Chinese women; ages 48–58 years; pre-, peri- or post-menopausal; participating in the Study of Women's Health Across the Nation Sleep Study (SWAN Sleep Study). Interventions: None. Measurements and Results: Measures included PSG-assessed sleep duration, continuity, and architecture, delta sleep ratio (DSR) computed from automated counts of delta wave activity, daily diary-assessed vasomotor symptoms (VMS), questionnaires to collect mood (depression, anxiety) symptoms, medication, and lifestyle information, and menopausal status using bleeding criteria. Sleep outcomes were modeled using linear regression. Nocturnal VMS were associated with longer sleep time. Higher anxiety symptom scores were associated with longer sleep latency and lower sleep efficiency, but only in women reporting nocturnal VMS. Contrary to expectations, VMS and mood symptoms were unrelated to either DSR or REM latency. Conclusions: Vasomotor symptoms moderated associations of anxiety with EEG sleep measures of sleep latency and sleep efficiency and was associated with longer sleep duration in this multi-ethnic sample of midlife women. Citation: Kravitz HM; Avery E; Sowers MF; Bromberger JT; Owens JF; Matthews KA; Hall M; Zheng H; Gold EB; Buysse DJ. Relationships between menopausal and mood symptoms and Eeg sleep measures in a multi-ethnic sample of middle-aged women: the SWAN Sleep Study. SLEEP 2011;34(9):1221-1232. PMID:21886360

  17. Community structure of the macrobenthos of an important Belgian wintering area for the Common Scoter (Melanitta nigra)

    OpenAIRE

    Degraer, S.; Vincx, M.; P. Meire; Offringa, H

    1998-01-01

    The shallow western Belgian Coastbanks are important wintering areas for the Common Scoters, reflecting the ecological importance of this environment. The diet of these seaducks consists of macrobenthos, mainly bivalves. The availability of these bivalves along the Belgian west-coast has been poorly documented and it is not clear to what extent the spatial distribution of the Scoters and the bivalves are linked. In October 1994, 40 macrobenthic samples were taken in the area. Multivariate tec...

  18. Working Paper 12-03 - An assessment of the risks to the medium-term outlook of the Belgian international economic environment

    OpenAIRE

    Eric Meyermans; Patrick Van Brusselen

    2003-01-01

    Each year, the Federal Planning Bureau (fpb) prepares a medium-term outlook for the Belgian economy with its macro-econometric hermes model. One of the key inputs of this exercise is a baseline scenario for the Belgian international economic environment, which includes an outlook for the output, imports, prices and financial variables of the major trading partners of Belgium. Traditionally, this international environment is based on the medium-term outlook presented by the European Commission...

  19. An experiment in democracy: observing the Belgian local partnerships for the management of low-level radioactive waste

    International Nuclear Information System (INIS)

    Observations are offered on the FSC workshop and the Belgian local partnerships from the perspective of public participation theory and practice. A distinction is drawn between participatory democratic theory and pluralism in order to point out that partnerships exemplify the latter and are thus susceptible to the main shortcoming of pluralism, which is that the stakeholders become a club of experts, distant from the individual citizens. A model of risk decision making based on the notions of analysis and deliberation is presented as a means for analytically scrutinizing the workshop and the partnerships. The workshop successfully diversified deliberation by invoking numerous features including: Small group work, informal venues, stimulating short presentations, involvement of local stakeholders, rapporteurs, community visits, and structured discussion. One shortcoming of the workshop was that it could have displayed more continuity with previous workshops and also convey a sense of progress on the issues of interest. A second shortcoming was that it invoked a very singular dimension of risk (to human health) without devoting adequate attention to the other dimensions of risk (economic, ecological, psychological, sociological, and ethical). The partnerships performed well in many ways; in particular the following features were evaluated as being positive: genuine commitment by partnership staff and leadership to involve all stakeholders, some degree of self-selection by participants (voluntary participation), widespread education and outreach, a flexible timetable, genuine commitment from ONDRAF/NIRAS to see the process through, clear, capable, and respected leadership. Finally, the simple survival of the partnerships in Mal and Dessel suggest popular legitimacy and buy-in by participants. A handful of more critical observations were made about the partnerships as well. First, the near absence of women strikes a chord of concern that women may not feel comfortable

  20. Accidental release of iodine 131 by the IRE of the Fleurus site: return on experience by the Belgian safety authority

    International Nuclear Information System (INIS)

    After a presentation of the activities of the IRE, the Belgian National Institute of Radio-elements, i.e. the production of radionuclides used in nuclear medicine, this report describes the process and chemical reaction which caused an accidental release of iodine 131. It analyzes the causes of this incident, and how the incident has been managed by the Belgian safety authority. It discusses the first assessment of radiological consequences, describes how the incident has been managed at the federal level, and how population and media have been informed. It discusses the actual radiological consequences through measurements performed on grass and vegetables (graphs and maps indicate contamination levels and contaminated areas), and through the assessment of exposure of adults and children by different ways. Lessons learned are then discussed

  1. Comparing TCM textbook descriptions of menopausal syndrome with the lived experience of London women at midlife and the implications for Chinese medicine research.

    Science.gov (United States)

    Scheid, Volker; Ward, Trina; Tuffrey, Veronica

    2010-08-01

    Almost without exception clinical research seeking to evaluate the effectiveness of Chinese medicine relies on TCM textbook knowledge - accessed directly or via practitioners' clinical usage - in order to frame its hypotheses. Recent historical research shows that these textbooks, products of a politically directed process of modernisation, constitute complex hybrids of western and Chinese knowledge that are designed to facilitate the integration of Chinese medicine into biomedically dominated contexts of practice. As such they produce a number of unresolved and generally unacknowledged tensions, such as between the emphasis on local illness experience in the Chinese medical tradition and the universality aspired to by biomedical knowledge. To examine the effect of these tensions we have carried out a study that compares local symptom patterns experienced by post-menopausal women in London with the universal patterns described in TCM textbooks. The results of this study confirm our proposition, namely that the TCM textbook descriptions of disease are not always grounded in clinical experience even if that is what textbooks claim. This raises questions about the relation of textbooks to clinical practice, and about the validity of clinical research based on textbooks and textbook derived normative practice. We argue that only a multidisciplinary approach that includes an understanding of the historical construction of contemporary Chinese medical knowledge and its relation to clinical practice can overcome these problems and enable a meaningful evaluation and utilisation of Chinese medicine in the context of 21st century evidence-based healthcare. PMID:20444560

  2. Effects of Strategic Human Resource Alignment Mechanisms on Firm Productivity in Belgian Medium-sized and Large Enterprises.

    OpenAIRE

    De Feyter, Tim; Guerry, Marie-Anne

    2010-01-01

    This article studies the relationships of different strategic human resource alignment mechanisms and firms productivity, by using data on 610 Belgian medium-sized and large enterprises. The results show that efforts to achieve a fit between strategic objectives and human resource practices are associated with higher productivity, regardless the alignment mode. Furthermore, it is found that organizational capacities to adapt to changing circumstances and employee remuneration are important co...

  3. Case report : A suspicion of cortico-cerebral necrosis in a Belgian Blue herd after ingestion of moulded silage

    OpenAIRE

    Guyot, Hugues; Sandersen, Charlotte; Aliaoui, Hamani; Brihoum, Mounir; Vandeputte, Sébastien; Rollin, Frédéric

    2004-01-01

    After ingestion of moulded beet pulp silage, cases of cortico-cerebral necrosis (CCN) and mortalities have been observed in a Belgian Blue (BB) herd. Contamination with Paecilomyces spp., a mould that produces byssochlamic acid, malformins and patulin, has been proven. Among these toxins, patulin is known to have cancerogenic, immunosuppressive and tremorgenic effects, but also acts on the respiratory and digestive systems. Twenty-five days after progressive introduction of bee...

  4. Hydroclimatic modulation of diatom/Phaeocystis blooms in nutrient-enriched Belgian coastal waters (North Sea)

    OpenAIRE

    Breton, E.; Rousseau, V.; Parent, J.-Y.; Ozer, J.; C. Lancelot

    2006-01-01

    Statistical analysis of 14 yr (1988-2001) of intensive phytoplankton monitoring at Station 330 in the central Belgian Coastal Zone (BCZ, Southern Bight of the North Sea) indicates that the long-term diatom biomass trend and the spring dominance of Phaeocystis colonies over diatoms are determined by the combined effect of the North Atlantic Oscillation (NAO) and freshwater and continental nitrate carried by the Scheldt. The strong correlation between diatoms and the NAO index is largely explai...

  5. School assessment policy and practice in Belgian secondary education with specific reference to vocational education and training

    OpenAIRE

    Verhoeven, Jef; Devos, Geert

    2005-01-01

    This paper describes the relationship between assessment practices and assessment policy and between general policy and assessment policy as teachers experience it in Belgian secondary schools in Flanders. Since the attainment targets of general, technical, and vocational education are different, this research explored whether teachers in the three forms of secondary education define these relationships differently. Our results enable us to argue that teachers in vocational education appear ...

  6. A stop-gain in the laminin, alpha 3 gene causes recessive junctional epidermolysis bullosa in Belgian Blue cattle

    OpenAIRE

    Sartelet, Arnaud; Harland, Chad; Tamma, Nico; Karim, Latifa; Bayrou, Calixte; Li, Wanbo; Ahariz, Naïma; Coppieters, Wouter; Georges, Michel; Charlier, Carole

    2015-01-01

    Four newborn purebred Belgian Blue calves presenting a severe form of epidermolysis bullosa were recently referred to our heredo-surveillance platform. SNP array genotyping followed by autozygosity mapping located the causative gene in a 8.3-Mb interval on bovine chromosome 24. Combining information from (i) whole-genome sequencing of an affected calf, (ii) transcriptomic data from a panel of tissues and (iii) a list of functionally ranked positional candidates pinpointed a private G to A nuc...

  7. Serosurvey for viruses associated with reproductive failure in newly introduced gilts and in multiparous sows in Belgian sow herds

    OpenAIRE

    Lefebvre, David; Van Reeth, Kristien; Vangroenweghe, Fr; Maes, Dominiek; Van Driessche, E; Laitat, M.; Nauwynck, Hans

    2009-01-01

    A serosurvey for viruses associated with reproductive disorders was conducted in 25 conventional Belgian farms. Serum antibody titers for porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), porcine parvovirus (PPV), porcine enteroviruses (PEV) and swine influenza viruses (SIV) were determined in gilts and sows. All the animals were seropositive for PCV2 and >95% were seropositive for all 4 embryopathogenic PEV serotypes. Consequently, special prevent...

  8. A generalised dynamic factor model for the Belgian economy - Useful business cycle indicators and GDP growth forecasts

    OpenAIRE

    Christophe Van Nieuwenhuyze

    2006-01-01

    This paper aims to extract the common variation in a data set of 509 conjunctural series as an indication of the Belgian business cycle. The data set contains information on business and consumer surveys of Belgium and its neighbouring countries, macroeconomic variables and some worldwide watched indicators such as the ISM and the OECD confidence indicators. The statistical framework used is the One-sided Generalised Dynamic Factor Model developed by Forni, Hallin, Lippi and Reichlin (2005). ...

  9. Structural and functional biological assessment of aggregate dredging intensity on the Belgian part of the North Sea

    OpenAIRE

    Backer, A De; Hillewaert, H.; Van Hoey, G; Wittoeck, J.; Hostens, K.

    2014-01-01

    Marine aggregate dredging in the Belgian part of the North Sea (BPNS) is restricted to four dedicated concession zones. Within these zones, there are areas under different dredging pressure, but with the advantage that these are situated within a similar habitat (cfr. similar sediment characteristics) . As such, this study assessed how different degrees of dredging pressure executed on a similar sandy habitat affect the benthic ecosystem. Possible responses of the macrobenthos on the dredging...

  10. Confirmed Zika virus infection in a Belgian traveler returning from Guatemala, and the diagnostic challenges of imported cases into Europe.

    Science.gov (United States)

    De Smet, Birgit; Van den Bossche, Dorien; van de Werve, Charlotte; Mairesse, Jacques; Schmidt-Chanasit, Jonas; Michiels, Jo; Ariën, Kevin K; Van Esbroeck, Marjan; Cnops, Lieselotte

    2016-07-01

    We report the first laboratory-confirmed Zika virus (ZIKV) infection in a Belgian traveler after a three week holiday in Guatemala, December 2015. This case along with other imported cases into Europe emphases once again the need for accurate diagnostic tools for this rapidly emerging virus. The challenge is to diagnose patients in the acute phase, which appears short, as serological testing is complicated by cross-reactivity, vaccination status and scarce availability of specific ZIKV tests. PMID:27128355

  11. Ecological status evaluation of the quality element macro-invertebrates for the Belgian coast (2007-2009)

    OpenAIRE

    Van Hoey, G.; Derweduwen, J; Hillewaert, H.; Hostens, K.; Pecceu, E.; Wittoeck, J.

    2010-01-01

    The Water Framework Directive (WFD; 2000/60/EG) aims to achieve a good ecological and chemical quality status of the European waters (Rivers, Lakes, coastal- and transitional waters). The quality status is determined based on the evaluation of different quality elements, e.g. macro-invertebrates. Macro-invertebrates are good indicators for detecting anthropogenic impacts and ecological degradation. The Belgian Coastal water body (< 1 nautical mile) is a small area, but this environment is hig...

  12. «One Difference Is Enough»: Towards a History of Disability in Belgian Congo (1908-1960

    Directory of Open Access Journals (Sweden)

    Evelyne Verhaegen

    2015-11-01

    Full Text Available This article aims to investigate the educational initiatives provided for Congolese people with disabilities during the Belgian colonization, 1908-1960. We found out disability strongly influenced the foundation of the Belgian colony and that it can be assumed that a significant number of Congolese in the Belgian colony were disabled. Yet no historical research about this subject can be found. The subject seemed to be hardly neglected and overlooked. It is this particular contradiction or silence in historiography that this article wants to elucidate. For this purpose, various and sometimes conflicting sources have been consulted. In addition to basic literature on the Belgian colonization and more specific literature on disability in relation to culture, various archives, such as audiovisual material and oral witnesses of this particular period have been included in this research. Our main finding is that in most of the colonial period little or no educational initiatives were provided for Congolese people with disabilities. This we explain by the very limited differentiation which was made between the Congolese themselves. We argue that the black man as such was considered as a rather alien figure and consequently the additional factor of disability remained hardly unnoticed. In the last years of the colonization an increased amount of educational initiatives emerged, which this article explains by the probable increased differentiation between blacks towards the end of the colonization. How to reference this article Verhaegen, E., Verstraete, P., & Depaepe, M. (2016. «One Difference Is Enough»: Hacia una historia de la discapacidad en el Congo Belga (1908-1960. Espacio, Tiempo y Educación, 3(1, 407-420. doi: http://dx.doi.org/10.14516/ete.2016.003.001.19

  13. Economic Importance of the Belgian Ports: Report 2005. Flemish maritime ports and Liège port complex

    OpenAIRE

    Lagneaux, Frédéric

    2007-01-01

    This paper is an annual publication issued by the Microeconomic Analysis service of the National Bank of Belgium. The Flemish maritime ports - Antwerp, Ghent, Ostend, Zeebrugge - and the Autonomous Port of Liège play a major role in their respective regional economies and in the Belgian economy, not only in terms of industrial activity but also as intermodal centres facilitating the commodity flow. This update paper provides an extensive overview of the economic importance and development of ...

  14. Economic Importance of the Belgian Ports : Report 2005. Flemish maritime ports and Liège port complex

    OpenAIRE

    Frédéric Lagneaux

    2007-01-01

    This paper is an annual publication issued by the Microeconomic Analysis service of the National Bank of Belgium. The Flemish maritime ports - Antwerp, Ghent, Ostend, Zeebrugge - and the Autonomous Port of Liège play a major role in their respective regional economies and in the Belgian economy, not only in terms of industrial activity but also as intermodal centres facilitating the commodity flow. This update paper provides an extensive overview of the economic importance and development of ...

  15. The HELENA online food frequency questionnaire: reproducibility and comparison with four 24-hour recalls in Belgian-Flemish adolescents

    OpenAIRE

    Vereecken, Carine; De Bourdeaudhuij, Ilse; Maes, Lea

    2010-01-01

    Abstract Objectives To investigate the reproducibility of the HELENA food frequency questionnaire (FFQ), developed as a basis for an online tailored intervention and to compare the FFQ with four computerized 24-hour recalls. Subjects/methods A convenience sample of 48 Belgian-Flemish adolescents completed four computerized 24-hour recalls, the FFQ and a retest one to two weeks later. Correlations, the Wilcoxons Signed Rank test and Bland and Altmans plots were used to...

  16. Radical pluralism and free speech in online public spaces: the case of North Belgian extreme right discourses

    OpenAIRE

    Cammaerts, Bart

    2009-01-01

    Progressive political movements and activists are not the only ones appropriating Web 2.0 as a way to construct independent public spaces and voice counterhegemonic discourses. By looking at the other extreme of (post-)fascist movements, it will be shown that the internet also gives rise to anti-public spaces, voicing hatred and essentialist discourses. In this article, discourses of hate produced by North-Belgian (post-)fascist movements and activists will be analysed. Theoretically the anal...

  17. Did the « Pax Electrica » agreements reduce the Suez’ power relationship on Elia, the Belgian electricity grid manager ?

    OpenAIRE

    Levy, Marc

    2009-01-01

    The company Elia, which manages the grid system of electricity in Belgium, is mainly controlled by the principal producer of electricity, Electrabel, and by political powers. The Belgian state has recently constrained the French group to yield 3% of its stake in Elia as foreseen in the Pax Electrica agreements. This article studies the impact of this transfer by means of the Banzhaf index that measures the intensity of control. The results show that theoretically these agreements change the p...

  18. Looking for the European Voter: Split-Ticket Voting in the Belgian Regional and European Elections of 2009 and 2014

    Directory of Open Access Journals (Sweden)

    Camille Kelbel

    2016-02-01

    Full Text Available While European elections are often seen as remote from EU issues, considerations specifically linked to the EU came to the forefront in the wake of the 2014 European elections: the economic and financial crisis, the new process of designation of the European Commission President, and the alleged increase of Eurosceptic votes. This increased salience of political debates about the EU asks for a reconsideration of the ‘second-order nature’ of European elections. In this context, as in 2009, the Belgian electorate voted for the regional and European levels on the very same day. Belgian voters were thus offered the opportunity to split their ticket between both levels. This allows comparing the occurrence and determinants of these ‘immediate switching’ behaviours in 2014 with those of the presumably less politicized EP elections in 2009. We do that by employing the 2009 and 2014 PartiRep Election Study data. On the one hand, the article shows that split-ticket voting cannot be explained by economic voting, European identity, and attitudes towards integration in 2014. On the other hand, the unique configuration of the Belgian elections enables us to observe that the introduction of Spitzenkandidaten did enhance split-ticket voting for voters who could directly vote for this candidate (in Flanders, while this did not increase split-ticket voting among voters who could only indirectly support the candidate (in Wallonia.

  19. Improved Emergency Preparedness For Management Of The Food chain Via Stakeholder Involvement: Belgian and European Experience

    Energy Technology Data Exchange (ETDEWEB)

    Hardeman, Frank; Carle, Benny [SCK.CEN, the Belgian Nuclear Research Centre, Boeretang 200, 2400 Mol (Belgium); Turcanu, Catrinel [Universite Libre de Bruxelles, Av. F. Roosevelt 50, 1050 Brussels (Belgium); Vandecasteele, Christian [FANC, Federal Agency for Nuclear Control, Ravensteinstraat 36, 1000 Brussels (Belgium)

    2006-07-01

    Initiatives involving stakeholder engagement have gained increasing importance in sustainable decision making for many risk-related issues. This paper describes a Belgian experience within a European context related to food management options in the event of a radioactive contamination of the food chain. Under the auspices of the European Commission's 5. Framework Programme, the F.A.R.M.I.N.G. (F.A.R.M.I.N.G. 2000) project (co-ordinated by H.P.A.) a stakeholder network was established in a number of European countries, following a successful approach originally adopted in the UK. In a comparable approach, national working groups were thus established in Belgium, Finland, France and Greece in order to organise stakeholder panels and to discuss the outcomes of scientific and technical research related to management options for the food chain. The results of these panels were exchanged between participating Member States and on a wider international basis at the W.I.S.D.O.M.2. workshop in 2003. The F.A.R.M.I.N.G. project had many achievements and there were also several important lessons learned for Belgium (Vandecasteele et al., 2005): Firstly, many stakeholders showed a real interest in tackling problems relating to food chain contamination; Secondly, the Belgian agricultural system is very intensive and technically and economically optimised, making many of the options envisaged difficult to implement; thirdly, the applicability of management options is also limited by political and legal issues (e.g. competencies, environmental legislation), operational constraints (e.g. waste treatment, supplies of materials), societal and ethical aspects (e.g. milk disposal to sea, animal welfare), and economics (e.g. who pays the intervention cost?); fourthly, there is a now a greater awareness of these problems in both the food production sector and among the experts involved in emergency management; Fifthly, increased attention is now given in Belgium to the medium and

  20. Improved Emergency Preparedness For Management Of The Food chain Via Stakeholder Involvement: Belgian and European Experience

    International Nuclear Information System (INIS)

    Initiatives involving stakeholder engagement have gained increasing importance in sustainable decision making for many risk-related issues. This paper describes a Belgian experience within a European context related to food management options in the event of a radioactive contamination of the food chain. Under the auspices of the European Commission's 5. Framework Programme, the F.A.R.M.I.N.G. (F.A.R.M.I.N.G. 2000) project (co-ordinated by H.P.A.) a stakeholder network was established in a number of European countries, following a successful approach originally adopted in the UK. In a comparable approach, national working groups were thus established in Belgium, Finland, France and Greece in order to organise stakeholder panels and to discuss the outcomes of scientific and technical research related to management options for the food chain. The results of these panels were exchanged between participating Member States and on a wider international basis at the W.I.S.D.O.M.2. workshop in 2003. The F.A.R.M.I.N.G. project had many achievements and there were also several important lessons learned for Belgium (Vandecasteele et al., 2005): Firstly, many stakeholders showed a real interest in tackling problems relating to food chain contamination; Secondly, the Belgian agricultural system is very intensive and technically and economically optimised, making many of the options envisaged difficult to implement; thirdly, the applicability of management options is also limited by political and legal issues (e.g. competencies, environmental legislation), operational constraints (e.g. waste treatment, supplies of materials), societal and ethical aspects (e.g. milk disposal to sea, animal welfare), and economics (e.g. who pays the intervention cost?); fourthly, there is a now a greater awareness of these problems in both the food production sector and among the experts involved in emergency management; Fifthly, increased attention is now given in Belgium to the medium and long

  1. Modelling water and 36Cl cycling in a Belgian pine forest - Model for 36Cl cycling in a Belgian pine forest

    International Nuclear Information System (INIS)

    A simplified, 1-D soil-groundwater-vegetation model to represent the cycling of water and of 36Cl in a Belgian Scots pine forest is presented and discussed. The model contains a soil column with layers of different (but uniform) field capacity and soil porosity, which are penetrated by tree roots. Flow through porous media is assumed to circulate according to Darcy and Philips laws, using empirical soil hydraulic properties without recourse to Richards' equation. The vegetation is represented by means of a compartment model including simplified representation of sap flow, translocation and litterfall in relation to different parts of the tree. The water table height is variable according to the balance between precipitation, capillary rise, solar radiation, plant uptake and evapotranspiration. The influence of local fluvial sources of water can also be evaluated in a simplified way as a losing/gaining stream input to the soil column. Time dependent data on temperature, solar irradiation, rainfall, crop coefficient and leaf area index (LAI) are used as input to the model in order to calculate evapotranspiration and a simplified approach to foliar interception. The chlorine flux follows the water flux in both soil and the trees, using retardation in soil and experimentally measured translocation factors within the plant. The chlorine flux is optimised and validated with recourse to a previous 36Cl compartment model. Although considered to be a relatively simple model, initial results suggest a reasonable consistency between previously published water balance and field measurements in a Scots pine stand from the vicinity of Mol, Belgium. The mean soil water content is predicted to be around 25%, the plant water is stored in the order roots > plant above roots > leaf surfaces, water table height below ground fluctuates between 2.1 and 2.6 m compared with a measured water table height of 1.8 - 20 m and pine transpiration is less than 1.2 mm/d compared with a measured

  2. Modelling water and {sup 36}Cl cycling in a Belgian pine forest - Model for {sup 36}Cl cycling in a Belgian pine forest

    Energy Technology Data Exchange (ETDEWEB)

    Vives i Batlle, Jordi; Vandenhove, Hildegarde; Gielen, Sienke [Belgian Nuclear Research Centre, Boeretang 200, 2400 Mol (Belgium)

    2014-07-01

    A simplified, 1-D soil-groundwater-vegetation model to represent the cycling of water and of {sup 36}Cl in a Belgian Scots pine forest is presented and discussed. The model contains a soil column with layers of different (but uniform) field capacity and soil porosity, which are penetrated by tree roots. Flow through porous media is assumed to circulate according to Darcy and Philips laws, using empirical soil hydraulic properties without recourse to Richards' equation. The vegetation is represented by means of a compartment model including simplified representation of sap flow, translocation and litterfall in relation to different parts of the tree. The water table height is variable according to the balance between precipitation, capillary rise, solar radiation, plant uptake and evapotranspiration. The influence of local fluvial sources of water can also be evaluated in a simplified way as a losing/gaining stream input to the soil column. Time dependent data on temperature, solar irradiation, rainfall, crop coefficient and leaf area index (LAI) are used as input to the model in order to calculate evapotranspiration and a simplified approach to foliar interception. The chlorine flux follows the water flux in both soil and the trees, using retardation in soil and experimentally measured translocation factors within the plant. The chlorine flux is optimised and validated with recourse to a previous {sup 36}Cl compartment model. Although considered to be a relatively simple model, initial results suggest a reasonable consistency between previously published water balance and field measurements in a Scots pine stand from the vicinity of Mol, Belgium. The mean soil water content is predicted to be around 25%, the plant water is stored in the order roots > plant above roots > leaf surfaces, water table height below ground fluctuates between 2.1 and 2.6 m compared with a measured water table height of 1.8 - 20 m and pine transpiration is less than 1.2 mm/d compared

  3. A model reconstruction of riverine nutrient fluxes and eutrophication in the Belgian Coastal Zone since 1984

    Science.gov (United States)

    Passy, P.; Gypens, N.; Billen, G.; Garnier, J.; Thieu, V.; Rousseau, V.; Callens, J.; Parent, J.-Y.; Lancelot, C.

    2013-12-01

    The OSPAR convention signed in 1992 by 15 European states including Belgium and France pledged to reduce the nutrient (nitrogen N and phosphorus P) loads from land-based sources to the Channel and the North Sea to half of what they were in 1985. In this paper, we use a river basin-coastal sea chain model to describe the evolution of nutrient loads to the Belgian Costal Zone originating from the Seine, Somme and Scheldt watersheds from 1984 to 2007 in order to assess the N and P reduction with respect to the OSPAR goals and the resulting effect on coastal eutrophication, especially Phaeocystis blooms. Since the early 1990s, most nutrient reduction actions have been devoted to domestic and industrial wastewater treatment, resulting in a sharp P decrease between 1984 and 2007: from 260 to 90 kgP km- 2 for the Seine River and from 215 to 110 kgP km- 2 for the Scheldt River. In spite of improved N treatment of wastewater, there is no clear decrease of N loads, which mostly originate from leaching intensively cultivated arable lands. N fluxes at the outlet of the Seine and Scheldt rivers were, respectively, 1990 and 2210 kgN km- 2 in 1984 and 1830 and 1390 kgN km- 2 in 2007. However, this relatively low decrease appears to be more influenced by hydrological conditions than by better efficiency of N use in agriculture. We conclude from this analysis that the OSPAR objectives for P have been achieved, whereas for N radical changes in agricultural practices are still required. The P reduction achieved allows, for the period of concern, a 50% decrease of Phaeocystis colony blooms in the Belgian Coastal Zone, both in magnitude and duration. However, the simulated decrease, of maximum abundance, i.e., from 60 · 106 in 1984 to 30 · 106 cells l- 1 in 2007, is still insufficient when compared to the ecological-quality indicator of 4 · 106 cells l- 1. A further decrease of nutrients is still necessary to decrease undesirable blooms more satisfactorily.

  4. Levels of contamination for various pollutants present in Belgian human plasma

    Energy Technology Data Exchange (ETDEWEB)

    Wouwe, N. Van; Goeyens, L. [Scientific Inst. of Public Health, Brussels (Belgium); Covaci, A. [Toxicological Center, Univ. of Antwerp, Wilrijk (Belgium); Kannan, K. [Wadsworth Center, New York State Dept. of Health, Albany, NY (United States); Gordon, J.; Chu, A. [Xenobiotic Detection System Inc., Durham, NC (United States); Eppe, G.; Pauw, E. De [Center of Analysis of residues in Traces (CART), Univ. of Liege (Belgium)

    2004-09-15

    During the last century, numerous compounds, such as polychlorinated biphenyls (PCBs) or organochlorine pesticides (OCPs), were banned because of their bioaccumulative and toxic properties, while other compounds, such as polybrominated diphenyl ethers (PBDEs), appeared on the market and consequently in the environment. The experiences gained from accidents involving PBBs, PCBs or PCDD/Fs are useful to conduct scientific investigations focused on preventing similar catastrophies with the newly introduced compounds. Several studies have reported potential increase in the concentration of PBDEs in food and wildlife. Monitoring the levels of toxic chemicals is therefore useful to understand the exposure pathways, sources and trends. The aim of the paper is to present actual contamination's levels of various pollutants in human plasma from Belgium. Several classes of pollutants, such PCDD/Fs, PCBs and OCPs were determined in 20 human plasmas. In addition, perfluorooctanesulfonate (PFOS) and related fluorochemicals, which are of current concern, were measured. Although anticipated, concentrations of PBDEs in the same samples were not yet determined. Through this study, a good approximation of the contamination level in Belgian human is given, allowing thus comparison with concentrations observed in other countries.

  5. [The Belgian project for the prevention of cardiovascular diseases: a model of multifactorial prevention].

    Science.gov (United States)

    Kornitzer, M

    1989-01-01

    Résults are presented from the "belgian heart disease prevention project, part of the WHO european collaborative trial in the multifactorial prevention of coronary heart disease (CHD)". 19.409 men aged 40-59 yr took part; they were employed in thirty factories which formed the allocation units for a randomised controlled trial lasting 5-6 yr. The intervention package consisted largely of health education promoting a cholesterol-lowering diet, smoking cessation, weight control, physical activity, and treatment of arterial hypertension. A programme of information was supplemented by face-to-face counselling at the workplace by two physicians attached to the project. The coronary risk profile was reduced in the intervention group, compared with that in the control group, especially during the first 4 yr, by effects on serum cholesterol, number of cigarettes smoked daily, and arterial blood-pressure. Total mortality was 17.5% lower in the intervention group than in the control group (p = 0.038); coronary mortality was reduced by a non-significant 20.8% whereas CHD incidence (non-fatal myocardial infarction plus fatal myocardial infarction plus sudden deaths) was reduced by 24.5%, (P = 0.031). Non-fatal myocardial infarction (not a major end-point) was similarly reduced by 26.1% (p = 0.030). PMID:2679938

  6. Media content analysis of the Fukushima accident in two Belgian newspapers

    International Nuclear Information System (INIS)

    In case of a nuclear accident, the media play a major role in communicating with the public. It is therefore crucial to know what messages are the media delivering in a nuclear emergency and how do they frame the event. Analysing the media reporting on the Fukushima nuclear accident can benefit nuclear emergency management in two major aspects. On the one hand, such analysis shows how to deliver risk messages effectively through the media and on the other hand, it brings insights into the information that has to be communicated by the emergency managers to the mass media. The media analysis of the nuclear accident in Fukushima reported here was done by means of discourse and content analysis. The coding method followed explicit rules of coding and enabled large quantities of data to be categorized. The newspapers included in the analysis were the Belgian newspapers Le Soir (French language) and De Standaard (Dutch language). The media news were obtained from press clippings by Media data base at University Antwerp - MEDIARGUS for the period between 11th of March to 11th of May, 2011.

  7. Risk perception of the Belgian population. Results of the public opinion survey in 2009

    International Nuclear Information System (INIS)

    The SCK-CEN 2009 risk perception barometer is based on over 1000 Computer Assisted Personal Interviews, taken from persons selected to be representative for the Belgian 18+ population, and all realized in the period July and August 2009. An additional sample , N = 100 is taken from the for the population living in the communities of Lambusart and Wanfercee-Baulet in the municipality of Fleurus. Besides the classical background variables used to obtain the quota for representatively (age, language, habitat, gender and social class), we also included a series of questions assessing the communication and sociological context. The main topics in the survey were I) risk perception and confidence in authorities; II) Attitude towards science and technology and attitudes toward nuclear energy; III) stake holders engagement; IV)acceptance of legal norms for food products; v) media use; vi) evaluation of nuclear actors; VII) psychometric risk characteristics; VII) safety behaviour and anomy; ix) knowledge about nuclear domain; x) risk communication; xi) consumer's attitude towards food with radioactive contamination. Some of the questions asked in 2009 are similar to those enquired in the SCK barometer of 2006 and 2002, in order to study the time evolution of the risk perception associated with various issues.

  8. Balancing selection on CDH2 may be related to the behavioral features of the Belgian Malinois.

    Directory of Open Access Journals (Sweden)

    Xue Cao

    Full Text Available The Belgian Malinois (BM is an excellent working dog that typically shows a circling behavior when placed in a confined space. Moreover, individuals showing moderate running in circles (one kind of obsessive compulsive behavior in confined spaces typically show better work performance compared to those without the circling behavior or to those with a serious circling behavior (which can be defined as an obsessive compulsive disorder (OCD. To determine whether the candidate gene CDH2, Cadherin 2, which is associated with OCD in the Doberman pinscher breed of dogs and in humans, was linked with this behavioral character in the BM, population genetic analyses were performed on a BM population and a natural population of the Chinese indigenous dog (CID. Many genetic signals of balancing selection were detected for one specific region of the CDH2 gene, which suggests that a genomic block, which is included in the CDH2 gene, experienced balancing selection in the BM, and that the CDH2 gene might be associated with the behavioral characteristics of the BM dog (a balance between circling behavior and work performance. Moreover one specific variant, G63913941A, which creates a predicted transcription factor-binding site, may be the key mutation in the CDH2 gene affecting the behavior of BMs by allowing the binding of a transcription factor and increasing CDH2 expression.

  9. Network inter-connectivity and capacity reservation behaviour: an investigation of the Belgian gas transmission network

    International Nuclear Information System (INIS)

    Lack of cross-border integration explains largely why natural gas markets remain basically national in scope, with levels of concentration similarly high as when the liberalization process commenced. This paper presents the results of an assessment of the upstream/downstream capacity of the Belgian natural gas transmission network which is highly interconnected with adjacent networks and fosters important transit activities. It is shown that the tendency to a better market coupling still suffers from important mismatches of capacity provisions on both sides of cross-border interconnections. Moreover, shippers use gas transmission networks more and more from a commercial portfolio perspective which goes beyond the traditional security of supply purpose of network designs. Capacity booking rates appear to be significantly higher than the underlying physical gas flows. From these findings, the paper contributes to a better understanding of the market barrier created by contractual congestion at cross-border interconnection points. The paper argues that contractual congestion is a symptom of suboptimal cooperation of adjacent network operators and lack of effective mechanisms to bring booked but non-used capacity back to the market, rather than an indicator for an overall need to increase investment budgets. (authors)

  10. Identification of a novel idiopathic epilepsy locus in Belgian Shepherd dogs

    DEFF Research Database (Denmark)

    Seppälä, Eija H.; Koskinen, Lotta L.E.; Gulløv, Christina Hedal;

    2012-01-01

    Epilepsy is the most common neurological disorder in dogs, with an incidence ranging from 0.5% to up to 20% in particular breeds. Canine epilepsy can be etiologically defined as idiopathic or symptomatic. Epileptic seizures may be classified as focal with or without secondary generalization, or a...... mutation. It would establish the affected breed as a novel therapeutic model, help to develop a DNA test for breeding purposes and introduce a novel candidate gene for human idiopathic epilepsies.......Epilepsy is the most common neurological disorder in dogs, with an incidence ranging from 0.5% to up to 20% in particular breeds. Canine epilepsy can be etiologically defined as idiopathic or symptomatic. Epileptic seizures may be classified as focal with or without secondary generalization, or as...... primary generalized. Nine genes have been identified for symptomatic (storage diseases) and one for idiopathic epilepsy in different breeds. However, the genetic background of common canine epilepsies remains unknown. We have studied the clinical and genetic background of epilepsy in Belgian Shepherds. We...

  11. The Gay Men Sex Studies: prevalence of sexual dysfunctions in Belgian HIV+ gay men

    Directory of Open Access Journals (Sweden)

    Vansintejan J

    2013-04-01

    Full Text Available Johan Vansintejan, Joris Janssen, Erwin Van De Vijver, Jan Vandevoorde, Dirk Devroey Department of Family Medicine, Vrije Universiteit Brussel (VUB, Brussels, Belgium Abstract: The aim of this Internet-based survey was to investigate the prevalence and associated predictors of sexual dysfunctions in Belgian self-reported HIV-positive men who have sex with other men. Of the 72 participants, 56% had a mild-to-severe erectile dysfunction, and 15% reported a hypoactive sexual desire disorder. The prevalence of premature ejaculation and anodyspareunia was 18% for both. Independent predictors for erectile dysfunction were frequency of masturbation, frequency of sex with partner, use of erectile enhancement drugs, having a passive sex role, and not having a steady relationship. Independent predictors for hypoactive sexual desire disorder were frequency of masturbation and having a lower lifetime number of sexual partners. Independent predictors for premature ejaculation were not having a steady relationship, having a lower lifetime number of sexual partners, and a lower level of education. The only independent predictor for anodyspareunia was having an active sex role. Keywords: homosexuality/male, sexual dysfunction, HIV, epidemiology

  12. PCBs and OCPs in marine species from the Belgian North Sea and the Western Scheldt Estuary

    Energy Technology Data Exchange (ETDEWEB)

    Voorspoels, S.; Covaci, A.; Maervoet, J.; Schepens, P. [Antwerp Univ., Wilrijk (Belgium). Toxicological Centre

    2004-09-15

    The use and/or production of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs), such as 2,2-bis-(4-chlorophenyl)-1,1,1-trichloroethane (DDT), hexachlorobenzene (HCB) and lindane ({gamma}-HCH) have been banned in most developed countries since the 1970's. Despite this measure, these compounds are among the most prevalent environmental pollutants and they can be found in various environmental compartments, both biotic and abiotic. Their widespread presence is due to their extremely persistant and lipophilic nature, resulting in enrichment throughout the food chain. Prolonged exposure to these pollutants can interfere with normal physiology and biochemistry3, resulting in adverse effects in various organisms, including starfish, shrimp, crabs, and fish4. Because humans readily consume seafood, such as shrimp, crab and various fish species, these organisms are of great scientific value to estimate the possible exposure to PCBs and OCPs through marine food sources. The area studied in this investigation covered both commercial fishing grounds (Belgian North Sea - BNS) and a recreational fishing area (Western Scheldt Estuary - SE). The drainage basin of the SE covers a very densely populated and highly industrialised region, causing a high level of pollution in the SE. In this work, PCBs and OCPs were determined in benthic invertebrates and different fish species from both BNS and SE in order to evaluate trends in levels, congener distribution, and geographical variation.

  13. Radiation dose to premature new-borns in the belgian neonatal intensive care units

    International Nuclear Information System (INIS)

    In the neonatal intensive care units (NICU), premature new-borns may be exposed to important doses. Because of their increased radiosensitivity and longer life expectancy, dose optimisation is of importance. The present study aimed at evaluating the dose of the most common radiographs in the Belgian NICU. Entrance surface kerma (ESK) and kerma area product (KAP) were collected in 17 NICU (among 19 in Belgium). Median ESK ranged from 13 to 172 μGy and from 8 to 117 μGy for chest and combined chest-abdomen radiographs, respectively; median KAP ranged from 1.4 to 14.2 mGy cm2 and from 3.8 to 28.1 mGy cm2 for chest and combined chest-abdomen radiographs, respectively. Those differences were due to large variations in the examination settings. Diagnostic reference levels (DRL) were set for chest and combined chest-abdomen radiographs. Though the radiograph dose was usually low, the cumulative dose per stay could be high. The wide, intercentre differences indicate that there is scope for dose reduction. The use of DRL should contribute to achieve this object. (authors)

  14. Risk perception of the Belgian population. Results of the public opinion survey in 2009

    Energy Technology Data Exchange (ETDEWEB)

    Perko, T.; Turcanu, C.; Schroeder, J.; Carle, B.

    2010-02-15

    The SCK-CEN 2009 risk perception barometer is based on over 1000 Computer Assisted Personal Interviews, taken from persons selected to be representative for the Belgian 18+ population, and all realized in the period July and August 2009. An additional sample , N = 100 is taken from the for the population living in the communities of Lambusart and Wanfercee-Baulet in the municipality of Fleurus. Besides the classical background variables used to obtain the quota for representatively (age, language, habitat, gender and social class), we also included a series of questions assessing the communication and sociological context. The main topics in the survey were I) risk perception and confidence in authorities; II) Attitude towards science and technology and attitudes toward nuclear energy; III) stake holders engagement; IV)acceptance of legal norms for food products; v) media use; vi) evaluation of nuclear actors; VII) psychometric risk characteristics; VII) safety behaviour and anomy; ix) knowledge about nuclear domain; x) risk communication; xi) consumer's attitude towards food with radioactive contamination. Some of the questions asked in 2009 are similar to those enquired in the SCK barometer of 2006 and 2002, in order to study the time evolution of the risk perception associated with various issues.

  15. Evolution of marine storminess in the Belgian part of the North Sea

    Directory of Open Access Journals (Sweden)

    D. Van den Eynde

    2012-02-01

    Full Text Available Severe storms have affected European coast lines in the past but knowledge on changes in storminess for the last decades is still sparse. Climate change is assumed to be a main driving factor with the potential to induce changes on the intensity, duration and frequency of powerful marine storms, including a long-term influence on peak wind speeds, surges and waves. It is, therefore, important to investigate whether in the last decades changes in the magnitude of storms, their duration and frequency could be observed. Understanding trends in storminess in the last decades will help to better prepare coastal managers for future events, taking into account potential changes on storm occurrence and magnitude to improve planning of mitigation and adaptation strategies. The purpose of this study was to focus on the evolution of extreme wind conditions, wave height and storm surge levels in the North Sea Region, especially in the Belgian part of the North Sea (BPNS. Based on the analysis performed it is concluded that no clear trend can be observed for the occurrence of significant increasing extreme wind speeds over the BPNS. Furthermore, one can conclude that not enough scientific evidence is available to support scenarios with increased wave height or storminess.

  16. Floating seaweed in the neustonic environment: A case study from Belgian coastal waters

    Science.gov (United States)

    Vandendriessche, Sofie; Vincx, Magda; Degraer, Steven

    2006-02-01

    Floating seaweeds form the most important natural component of all floating material found on the surface of oceans and seas. Notwithstanding the absence of natural rocky shores, ephemeral floating seaweed clumps are frequently encountered along the Belgian coast. From October 2002 to April 2003, seaweed samples and control samples (i.e. surface water samples from a seaweed-free area) were collected every other week. Multivariate analysis on neustonic macrofaunal abundances showed significant differences between seaweed and control samples in the fraction > 1 mm. Differences were less conspicuous in the 0.5-1 mm fraction. Seaweed samples were characterised by the presence of seaweed fauna e.g. Acari, Idotea baltica, Gammarus sp ., while control samples mainly contained Calanoida, Larvacea, Chaetognatha, and planktonic larvae of crustaceans and polychaetes. Seaweed samples (1 mm fraction) harboured considerably higher diversities (× 3), densities (× 18) and biomasses (× 49) compared to the surrounding water column (control samples). The impact of floating seaweeds on the neustonic environment was quantified by the calculation of the added values of seaweed samples considering biomass and density. These calculations resulted in mean added values of 311 ind m - 2 in density and 305 mg ADW m - 2 in biomass. The association degree per species was expressed as the mean percentage of individuals found in seaweed samples in proportion to the total density and biomass of that species (seaweed samples + control samples). Thirteen species showed an association percentage > 95%, and can therefore be considered members of the floating seaweed fauna.

  17. Risk factors and effect of selective removal on retroviral infections prevalence in Belgian stray cats.

    Science.gov (United States)

    Garigliany, M; Jolly, S; Dive, M; Bayrou, C; Berthemin, S; Robin, P; Godenir, R; Petry, J; Dahout, S; Cassart, D; Thiry, E; Desmecht, D; Saegerman, C

    2016-01-01

    The aim of this study was to evaluate the effect of several risk/protective factors and predictors on the prevalence of feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) infections in 302 stray cats captured during a trap-neuter-release programme in a mixed urban-rural area from Belgium, from 2010 to 2012. The impact of selective removal of FIV-positive cats on the apparent prevalence in the remaining population over this three-year period was also assessed. The seroprevalences over three years were 18.8 per cent for FIV and 0.7 per cent for FeLV. For FIV, the seroprevalence decreased significantly from the first year of the programme (2010; 30.5 per cent) to the last (2012; 13.1 per cent). Sex (male) and age (adult and old cats) were risk factors, while the year of sampling (years 2011 and 2012) was a protective factor. Age, sex and location were the most relevant predictors of FIV status. The data presented in this study revealed a very high FIV seroprevalence in Belgian stray cats, while FeLV was almost absent. The selective removal of positive cats had a drastic effect on the FIV seroprevalence in the remaining cat population. PMID:26744011

  18. Phasic or terminal detrusor overactivity in women: age, urodynamic findings and sphincter behavior relationships

    Directory of Open Access Journals (Sweden)

    Françoise A. Valentini

    2011-12-01

    Full Text Available OBJECTIVES: To search for relationships between phasic (P and terminal (T DO with age, urodynamic findings and sphincter behavior during involuntary detrusor contraction in woman. MATERIALS AND METHODS: Urodynamic studies (triple lumen catheter 7F, seated position of 164 successive women referred for LUTS with diagnosis of DO were reviewed. Patients were stratified in 4 sub-groups: pre- (18-44y, peri- (45-54 y, post-menopause (55-74 y and oldest old (≥ 75 y. The urethral sensor was positioned at the level of the maximum urethral closure pressure for sphincter behavior analysis. A variation of at least 5 cmH2O in pressure (detrusor or urethra was chosen to assert DO or sphincter response. Sphincter response was classified as relaxation (re before or during DO, or steady (st. RESULTS: Occurrence of P and TDO was similar: 77 P and 87 T. The PDO group was significantly younger (p = 0.0003. TDO was more frequent in patients with a history of neurological disease. The percentage of PDO remained almost constant in age groups, while that of TDO increased with age from 6.7% to 23.2% (p = 0.0013. Uninhibited contraction occurred at a smaller bladder volume in the P group: 149 ± 95 vs. 221 ± 113 mL (p < 0.0001. Steady sphincter predominated in the TDO subgroup: 45.9% vs. 32.1% and increased significantly in each DO sub-group of ³ 75y. CONCLUSION: Steady sphincter during both P and TDO, and occurrence of TDO appear as specific of aging. The last result could be related to structural changes in the detrusor muscle with aging.

  19. Progestins in the menopause in healthy women and breast cancer patients.

    Science.gov (United States)

    Pasqualini, Jorge R

    2009-04-20

    At present, more than 200 progestin compounds are synthetized, but their biological effects are different: this is function of their structure, receptor affinity, metabolic transformations, the target tissues considered, dose. The action of progestins in breast cancer is controversial; some studies indicate an increase in breast cancer incidence, others show no differences, and yet others indicate a decrease. Many studies agree that treatment with progestins plus estrogens at a low dose and during a limited period (less than 5 years) can have beneficial effects in peri- and post-menopausal women. It was demonstrated that various progestins (e.g. nomegestrol acetate, medrogestone, promegestone), as well as tibolone and its metabolites, can block the enzymes involved in estradiol bioformation (sulfatase, 17beta-hydroxysteroid dehydrogenase) in breast cancer. Progesterone is converted into various metabolic products: in normal breast tissue the transformation is mainly to 4-ene derivatives, whereas in the tumor tissue 5alpha-pregane derivatives are predominant. Aromatase activity is the last step in the formation of estrogens by the conversion of androgens. In recent studies it was shown that 20alpha-dihydroprogesterone, a metabolite found mainly in normal breast tissue and having anti-proliferative properties, can act as an anti-aromatase agent. The data suggest the possible utilization of this compound in breast cancer prevention. In conclusion, in order to clarify and better understand the response of progestins in breast cancer (incidence and mortality), as well as in hormone replacement therapy or in endocrine dysfunction, new clinical trials are necessary using other progestins in function of the dose and period of treatment. PMID:19179024

  20. A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

    OpenAIRE

    Chen, Hao; Perez, Jessica N.; Constantopoulos, Eleni; McKee, Laurel; Regan, Jessica; Hoyer, Patricia B.; Brooks, Heddwen L.; Konhilas, John

    2014-01-01

    The risk of cardiovascular disease (CVD) increases in post-menopausal women, yet, the role of exercise, as a preventative measure for CVD risk in post-menopausal women has not been adequately studied. Accordingly, we investigated the impact of voluntary cage-wheel exercise and forced treadmill exercise on cardiac adaptation in menopausal mice. The most commonly used inducible model for mimicking menopause in women is the ovariectomized (OVX) rodent. However, the OVX model has a few dissimilar...

  1. From the Women's Health Initiative to the combination of estrogen and selective estrogen receptor modulators to avoid progestin addition.

    Science.gov (United States)

    Valera, Marie-Cécile; Gourdy, Pierre; Trémollières, Florence; Arnal, Jean-François

    2015-11-01

    The female life expectancy rose from an average of 48 years to over 80 years in a century. The decline in the endogenous production of estrogen (especially the main circulating physiological hormone, 17β-estradiol, E2) at menopause (51 years on average) often leads to functional disorders affecting the quality of life. Estrogen deficiency impacts different tissues and results in an increase of various diseases, such as osteoporosis or cardiovascular diseases. Hormone therapy (HT) for menopause is a rather new challenge which experienced vagaries following the women's health initiative (WHI) study conducted in largely post-menopausal women. In the first part of this review, we will try to summarize the main conclusions of the WHI trials, in particular the timing effect as well as the deleterious impact of the associated progestin, medroxyprogesterone acetate (MPA). Hormone therapy, particularly the conjugated equine estrogen (CEE) combined with the MPA favor the occurrence of breast cancer, whereas conversely selective estrogen receptor modulators (SERMs, such as tamoxifen or raloxifene) that block the activity of estrogen receptor alpha (ERa) prevent the risk of recurrence of ERa-positive breast cancers. A new strategy of ERa modulation called tissue selective estrogen complex (TSEC), combines (1) CEE to maintain the benefits of estrogen (climacteric symptoms and prevention of osteoporosis) and (2) bazedoxifene, which is not only a SERM, but which also induces a rapid degradation of ERa in the uterus and in the breast, thereby prevents the stimulatory effects of estrogens on epithelial proliferation of these two sex targets. In the second part of this review, we will summarize the recognized benefits of the TSEC approach, and our current knowledge of its potential benefits and risks. PMID:26261036

  2. Significance of Ovarian Function Suppression in Endocrine Therapy for Breast Cancer in Pre-Menopausal Women

    Science.gov (United States)

    Scharl, A.; Salterberg, A.

    2016-01-01

    Ovarian function suppression (OFS) for treating breast cancer in pre-menopausal women was introduced for the first time in the late 19th century as bilateral oophorectomy. It was not until the 1960s that the oestrogen receptor was identified and a test for detecting endocrine sensitivity of the breast cancer was developed. A weakness of early trials on OFS for breast cancer treatment is therefore their failure to take receptor sensitivity into account when selecting participants. A meta-analysis performed in the early 1990s first proved that adjuvant OFS significantly improved the cure rate of oestrogen receptor-positive breast cancer in pre-menopausal women regardless of whether it was carried out through oophorectomy, radiation-induced ablation or drug therapy. In the 1970s, tamoxifen was synthesized. It became one of the most important cancer drugs and today constitutes the gold standard for endocrine adjuvant therapy. Taking tamoxifen for a five-year period lowers mortality by 30 % over 15 years. Ten years of tamoxifen therapy reduces mortality even further, with increased side effects, however. Research over the past ten years has proven that for post-menopausal women, aromatase inhibitors have benefits over tamoxifen. Current trial results have rekindled the debate about the combination of OFS with tamoxifen or with aromatase inhibitors for adjuvant breast cancer treatment of pre-menopausal women. These trials have reported an improvement in disease-free survival in patients with a high risk of recurrence when they are treated with a combination of OFS plus tamoxifen or aromatase inhibitors, especially in women younger than 35. However, combination therapy causes significantly more side effects, which could negatively impact compliance. Endocrine treatments administered over a period of many years show waning compliance, which tends to be only around 50 % after five years. Inadequate compliance compromises efficacy and increases the risk of mortality. For

  3. Risk factors for major depression during midlife among a community sample of women with and without prior major depression: are they the same or different?

    Science.gov (United States)

    Bromberger, J. T.; Schott, L.; Kravitz, H. M.; Joffe, H.

    2015-01-01

    Background Women’s vulnerability for a first lifetime-onset of major depressive disorder (MDD) during midlife is substantial. It is unclear whether risk factors differ for first lifetime-onset and recurrent MDD. Identifying these risk factors can provide more focused depression screening and earlier intervention. This study aims to evaluate whether lifetime psychiatric and health histories, personality traits, menopausal status and factors that vary over time, e.g. symptoms, are independent risk factors for first-onset or recurrent MDD across 13 annual follow-ups. Method Four hundred and forty-three women, aged 42–52 years, enrolled in the Study of Women’s Health Across the Nation in Pittsburgh and participated in the Mental Health Study. Psychiatric interviews obtained information on lifetime psychiatric disorders at baseline and on occurrences of MDD episodes annually. Psychosocial and health-related data were collected annually. Cox multivariable analyses were conducted separately for women with and without a MDD history at baseline. Results Women without lifetime MDD at baseline had a lower risk of developing MDD during midlife than those with a prior MDD history (28% v. 59%) and their risk profiles differed. Health conditions prior to baseline and during followups perception of functioning (ps < 0.05) and vasomotor symptoms (VMS) (p = 0.08) were risk factors for first lifetime-onset MDD. Being peri- and post-menopausal, psychological symptoms and a prior anxiety disorder were predominant risk factors for MDD recurrence. Conclusions The menopausal transition warrants attention as a period of vulnerability to MDD recurrence, while health factors and VMS should be considered important risk factors for first lifetime-onset of MDD during midlife. PMID:25417760

  4. The Belgian PCB/dioxin incident: analysis of the food chain contamination and health risk evaluation.

    Science.gov (United States)

    Bernard, Alfred; Broeckaert, Fabrice; De Poorter, Geert; De Cock, Ann; Hermans, Cédric; Saegerman, Claude; Houins, Gilbert

    2002-01-01

    The Belgian PCB incident occurred at the end of January 1999 when a mixture of polychlorinated biphenyls (PCBs) contaminated with dioxins was accidentally added to a stock of recycled fat used in the production of animal feeds. Although signs of poultry poisoning were noticed by February, 1999, the source and the extent of the contamination were discovered only in May 1999, when it appeared that more than 2500 farms could have been supplied with contaminated feeds. This resulted in a major food crisis, which rapidly extended to the whole country and could be resolved only by the implementation of a large PCB/dioxin food monitoring program. Screening for PCB contamination was based on the determination of the seven PCB markers. When PCB concentrations exceeded the tolerance levels of 0.1 (milk), 0.2 (poultry, bovine, and pig meat), or 1 (animal feed) microg/g fat, dioxins (17 PCDD/Fs congeners) were also determined. At the end of December 1999, the database contained the results of more than 55,000 PCB and 500 dioxin analyses. The study of PCB levels and profiles in contaminated feeds delivered to poultry or pig farms confirmed that the Belgian PCB incident was due to a single source of PCB oil introduced into the food chain at the end of January 1999. This PCB oil had a congeners pattern closely matched to a mixture of Aroclor 1260/1254 in the proportion 75/25. The total amount of PCBs added to recycled fats was estimated at 50 kg (sum of the seven markers) or approximately 150 kg total PCBs, which corresponds to about 100 liters of PCB oil. This PCB mixture contained about 1g TEQ dioxins (more than 90- contributed by PCDFs) and about 2g TEQ dioxin-like PCBs. The proportions of PCB 52 and 101 congeners were fairly constant in animal feeds, excluding the possibility of secondary contamination due to fat recycling from contaminated animals. The highest concentrations of PCBs and dioxins were found in poultry and especially in the reproduction animals (hens and chicks

  5. Detection and identification of xerophilic fungi in Belgian chocolate confectionery factories.

    Science.gov (United States)

    De Clercq, Nikki; Van Coillie, Els; Van Pamel, Els; De Meulenaer, Bruno; Devlieghere, Frank; Vlaemynck, Geertrui

    2015-04-01

    Chocolate confectionery fillings are generally regarded as microbiologically stable. The stability of these fillings is largely due to the general practice of adding either alcohol or preservatives. Consumer demands are now stimulating producers to move away from adding alcohol or other preservatives to their confectionery fillings and instead to search for innovative formulations. Such changes in composition can influence the shelf life of the product and may lead to spoilage by xerophilic fungi. The aim of this study was to test whether the production environment of Belgian chocolate confectionery factories and common ingredients of chocolate confectioneries could be potential sources of contamination with xerophilic fungal species. In the factory environment, the general and strictly xerophilic fungal spore load was determined using an RCS Air Sampler device in combination with DG18 and MY50G medium, respectively. Four basic ingredients of chocolate confectionery fillings were also examined for fungal spore levels using a direct plating technique. Detected fungi were identified to species level by a combination of morphological characterization and sequence analysis. Results indicated a general fungal spore load in the range of 50-250 colony forming units per cubic meter of air (CFU/m(3) air) and a more strict xerophilic spore load below 50 CFU/m(3) air. These results indicate rather low levels of fungal spores present in the factory environment. The most prevalent fungi in the factory environment were identified as Penicillium spp., particularly Penicillium brevicompactum. Examination of the basic ingredients of confectionery fillings revealed nuts to be the most likely potential source of direct contamination. In nuts, the most prevalent fungal species identified were Eurotium, particularly Eurotium repens. PMID:25475302

  6. Losses of glyphosate and AMPA via drainflow in a typical Belgian residential area

    Science.gov (United States)

    Tang, Ting; Boënne, Wesley; van Griensven, Ann; Seuntjens, Piet; Bronders, Jan; Desmet, Nele

    2014-05-01

    Urban hard surfaces are considered as important facilitators for pesticide transport into urban streams. To obtain concurrent high-resolution data for a detailed investigation on the losses of pesticide runoff from hard surfaces, a monitoring campaign was performed in a typical Belgian residential area (9.5 ha) between 7 May and 7 August, 2013. The campaign yielded a concurrent dataset of rainfall (1-mm rainfall interval), discharge (1-min interval), glyphosate application by the residents and the occurrences of glyphosate and its major degradation product - aminomethylphosphonic acid (AMPA) in the separated storm drainage outflow during 12 rainfall events. In addition, detailed information was obtained on the spatial characteristics of the study area. The resulting dataset allows us to investigate the relevance of catchment hydrology, urban surface properties and pesticide application to the transport and losses of glyphosate in a residential environment. During the campaign, glyphosate was only applied by local residents, mainly on their private driveways. As a result of their continuous use, both glyphosate and AMPA were detected in all analysed outflow samples, with maximum concentrations of 6.1 μg/L and 5.8 μg/L, respectively. Overall, the storm drainage system collected 0.43% of the applied amount of glyphosate. However, this loss rate varied considerably among rainfall events, ranging from 0.04% to 23.36%. According to statistical analysis of the 12 rainfall events, the loss rate was significantly correlated with three factors: the application amount prior to a rainfall event (p glyphosate application and the start of the rainfall event (negatively, p glyphosate. Furthermore, three types of glyphosate runoff were classified by a clustering analysis based on these factors: events dominated by runoff availability (runoff-limited), dominated by glyphosate availability (pesticide-limited) and controlled by both runoff and glyphosate availability. To sum up

  7. The Belgian PCB/dioxin incident: a critical review of health risks evaluations.

    Science.gov (United States)

    Bernard, A; Fierens, S

    2002-01-01

    The Belgian PCB/dioxin incident is a food contamination that occurred in Belgium in January 1999 when a tank of recycled fats used to produce animal feeds was accidentally contaminated by approximately 100 L of polychlorinated biphenyl (PCB) oil containing 50 kg PCBs expressed as the sum of the seven markers, 1 g (TEQ) dioxins (PCDD/Fs) and 2 g toxic equivalent (TEQ) dioxin-like PCBs. The incident was discovered when a poultry poisoning resembling the classic chick edema disease broke out in several farms that had received contaminated feeds. The delay in making public this incident resulted in a major political and food crisis and caused much concern in the population. We review here the health risk evaluations that were made after this incident and we assess the likelihood of the different scenarios by taking into account recent data on the real scale of the contamination and on the dioxin body burden of the general population in Belgium. These new data confirm that the incident was too limited in time and in scale to have increased the PCB/dioxin body burden of the general population at large, a conclusion supported by a survey of dioxin levels in blood conducted at the end of 1999. Only farmers in poultry farms affected by the incident (about 30 farms) and having regularly consumed their own products could have increased their PCB/dioxin body burden. It is unlikely, however, that these farmers could have increased their PCB/dioxin body burden above levels prevailing in the 1980s or now found in communities regularly consuming seafood. PMID:12396678

  8. Active living neighborhoods: is neighborhood walkability a key element for Belgian adolescents?

    Directory of Open Access Journals (Sweden)

    De Meester Femke

    2012-01-01

    Full Text Available Abstract Background In adult research, neighborhood walkability has been acknowledged as an important construct among the built environmental correlates of physical activity. Research into this association has only recently been extended to adolescents and the current empirical evidence is not consistent. This study investigated whether neighborhood walkability and neighborhood socioeconomic status (SES are associated with physical activity among Belgian adolescents and whether the association between neighborhood walkability and physical activity is moderated by neighborhood SES and gender. Methods In Ghent (Belgium, 32 neighborhoods were selected based on GIS-based walkability and SES derived from census data. In total, 637 adolescents (aged 13-15 year, 49.6% male participated in the study. Physical activity was assessed using accelerometers and the Flemish Physical Activity Questionnaire. To analyze the associations between neighborhood walkability, neighborhood SES and individual physical activity, multivariate multi-level regression analyses were conducted. Results Only in low-SES neighborhoods, neighborhood walkability was positively associated with accelerometer-based moderate to vigorous physical activity and the average activity level expressed in counts/minute. For active transport to and from school, cycling for transport during leisure time and sport during leisure time no association with neighborhood walkability nor, with neighborhood SES was found. For walking for transport during leisure time a negative association with neighborhood SES was found. Gender did not moderate the associations of neighborhood walkability and SES with adolescent physical activity. Conclusions Neighborhood walkability was related to accelerometer-based physical activity only among adolescent boys and girls living in low-SES neighborhoods. The relation of built environment to adolescent physical activity may depend on the context.

  9. Criterion distances and correlates of active transportation to school in Belgian older adolescents

    Directory of Open Access Journals (Sweden)

    De Bourdeaudhuij Ilse

    2010-12-01

    Full Text Available Abstract Background Since physical activity levels in older adolescents have the potential to be increased by stimulating active transportation to school (ATS, the most important correlates of ATS should be determined before developing interventions, especially in those adolescents for whom the distance to school is feasible for active commuting. The main aims of this study were to determine criterion distances for ATS in Belgian older adolescents, to examine multidimensional correlates of ATS in adolescents living within a feasible distance from school and to investigate the associations of ATS with total physical activity and with other physical activities besides ATS. Methods In total, 1281 older adolescents (17-18 years from 20 general secondary schools in East- and West-Flanders completed a questionnaire on physical activity behaviors, demographic factors and psychosocial and physical environmental correlates of physical activity. Distance to school was objectively measured using Routenet online route planner. Results In total, 58.4% of the participants commuted actively to school. The criterion distance for ATS could be set at eight kilometers for cycling and two kilometers for walking. For those adolescents living within a feasible distance for ATS, gender, smoking status, walkability of the neighborhood and social modeling were associated with transportation mode choice. ATS was positively associated with total physical activity, but not significantly related to min/week of other physical activities. Conclusions For older adolescents living within eight kilometers of their school, interventions taking into account the correlates found to be related to ATS could possibly be effective to enhance ATS and to increase total physical activity levels. In the context of the overall physical activity decline in adolescence, also interventions targeting physical activity behaviors of adolescents living further away from school might be needed, but

  10. Opinion of Belgian Egg Farmers on Hen Welfare and Its Relationship with Housing Type

    Science.gov (United States)

    Stadig, Lisanne M.; Ampe, Bart A.; Van Gansbeke, Suzy; Van den Bogaert, Tom; D’Haenens, Evelien; Heerkens, Jasper L.T.; Tuyttens, Frank A.M.

    2015-01-01

    Simple Summary Until 2012, laying hens in the EU were often housed in conventional cages that offered limited space and few opportunities to perform highly motivated behaviors. Conventional cages are now banned in the EU in order to improve animal welfare. In this study, egg farmers were surveyed (winter 2013–2014) to assess whether they perceived any changes in animal welfare since changing housing systems, what role hen welfare played in choosing a new housing system, and which aspects of hen welfare they find most important. The data show that the answers differ depending on which housing system the farmers currently use and whether they had used conventional cages in the past. Abstract As of 2012, the EU has banned the use of conventional cages (CC) for laying hens, causing a shift in housing systems. This study’s aim was to gain insight into farmers’ opinions on hen health and welfare in their current housing systems. A survey was sent to 218 Belgian egg farmers, of which 127 (58.3%) responded, with 84 still active as egg farmer. Hen welfare tended to be less important in choosing the housing system for farmers with cage than with non-cage systems. Respondents currently using cage systems were more satisfied with hen health than respondents with non-cage systems. Reported mortality increased with farm size and was higher in furnished cages than in floor housing. Feather pecking, cannibalism, smothering and mortality were perceived to be higher in current housing systems than in CC, but only by respondents who shifted to non-cage systems from previously having had CC. Health- and production-related parameters were scored to be more important for hen welfare as compared to behavior-related parameters. Those without CC in the past rated factors relating to natural behavior to be more important for welfare than those with CC. This difference in opinion based on farmer backgrounds should be taken into account in future research. PMID:26703742

  11. Multiyear Serological Surveillance of Notifiable Influenza A Viruses in Belgian Poultry: A Retrospective Analysis.

    Science.gov (United States)

    Marché, Sylvie; Houdart, Philippe; van den Berg, Thierry; Lambrecht, Bénédicte

    2016-05-01

    Surveillance of notifiable avian influenza (NAI) virus is mandatory in European member states, and each year a serological survey is performed to detect H5 and H7 circulation in poultry holdings. In Belgium, this serological monitoring is a combination of a stratified and a risk-based approach and is applied to commercial holdings with more than 200 birds. Moreover, a competitive nucleoprotein (NP) ELISA has been used as first screening method since 2010. A retrospective analysis of the serological monitoring performed from 2007 through 2013 showed sporadic circulation of notifiable low-pathogenicity avian influenza (LPAI) viruses in Belgian holdings with a fluctuating apparent flock seroprevalence according to years and species. Overall, the highest apparent flock seroprevalence was detected for the H5 subtype in domestic Anatidae, with 20%-50% for breeding geese and 4%-9% for fattening ducks. Positive serology against non-H5/H7 viruses was also observed in the same species with the use of the IDScreen influenza A antibody competition ELISA kit (ID-vet NP ELISA), and confirmed by isolation of H2, H3, H6, and H9 LPAI viruses. Among Galliformes, the apparent flock seroprevalence was lower, ranging between 0.3% and 1.3%. Circulation of notifiable LPAI viruses was only observed in laying hens with a similar seroprevalence for H5 and H7. Based on ID-vet NP ELISA results, no circulation of LPAI viruses, regardless the subtype, was observed in breeding chickens and fattening turkeys. Retrospectively, the use of an ELISA as first-line test not only reduced the number of hemagglutination inhibition tests to be performed, but also gave a broader evaluation of the prevalence of LPAI viruses in general, and might help to identify the most at-risk farms. PMID:27309088

  12. An inquiry of the opinions of the French and Belgian populations as regards risk

    International Nuclear Information System (INIS)

    IRSN (France) and SCK-CEN (Belgium), two institutes of research and expertise in radiation protection and nuclear safety, simultaneously organised a very similar public opinion survey in their respective countries in November 2002. The study explores subjects such as: major people's concerns, perception of environmental risks, perception of risks in general, the role of experts in decision making, opinions on nuclear matters and aspects of nuclear emergency preparedness. In each country, more than 1000 citizens representing the general public have been consulted in face-to-face interviews. The field work has been performed by professional companies (BVA in France and Research International in Belgium). The paper shows that industrial and technological risks are not perceived as one of the major public concerns, although many other risks, of different nature are considered to be high. The actions of the authorities to provide protection against the consequences of many risks or disasters are not considered to be sufficient, and many respondents claim not to believe the information they receive. There exists a large difference between the opinion of French and Belgian public, and within the different language groups in Belgium, with regard to who should be in charge of the control of the hazardous industries. Many of the 'actors' within the nuclear industry are not known by the respondents. The perception of the technical competence or the truth being told shows large variations between the main actors (such as members of the nuclear industry, the government or the media). Majorities within the population believe that a disaster as serious as the Chernobyl one can happen in their country and that in case of a nuclear accident, the authorities would not be capable to protect the population adequately

  13. Neuropsychiatric Inventory data in a Belgian sample of elderly persons with and without dementia

    Directory of Open Access Journals (Sweden)

    Squelard GP

    2012-10-01

    Full Text Available Gilles P Squelard,1 Pierre A Missotten,1 Louis Paquay,2 Jan A De Lepeleire,2 Frank JVM Buntinx,2 Ovide Fontaine,1 Stephane R Adam,1 Michel JD Ylieff11Clinical Psychology of Ageing, Qualidem Research Project, University of Liège (ULg, Liège, Belgium; 2KU Leuven, Department of Public Health and Primary Care, Leuven, BelgiumBackground/aims: This study assesses and compares prevalence of psychological and behavioral symptoms in a Belgian sample of people with and without dementia.Methods: A total of 228 persons older than 65 years with dementia and a group of 64 non-demented persons were assessed using the Neuropsychiatric Inventory (NPI in 2004.Results: Within the group without dementia, the most frequent symptoms were depression, agitation, and irritability. Within the group with dementia, the most common symptoms were depression, irritability, apathy, and agitation. Prevalence of delusions (P < 0.05, hallucinations (P < 0.05, anxiety (P < 0.05, agitation (P < 0.05, apathy (P < 0.01, aberrant motor behavior (P < 0.01, and eating disorders (P < 0.05 were significantly higher in the group with dementia.Conclusion: Depression, elation, irritability, disinhibition, and sleeping disorders are not specific to dementia. Agitation, apathy, anxiety, and delusions are more frequent in dementia but were not specific to the dementia group because their prevalence rates were close to 10% in the group without dementia. Hallucinations, aberrant motor behavior, and eating disorders are specific to dementia. The distinction between specific and nonspecific symptoms may be useful for etiological research on biological, psychological, and environmental factors.Keywords: behavior, behavior disorders, epidemiology, dementia, psychiatric symptoms, neuropsychiatry

  14. Sampling, prevalence and characterization of methicillin-resistant Staphylococcus aureus on two Belgian pig farms

    Directory of Open Access Journals (Sweden)

    Isabelle Dewaele

    2011-02-01

    Full Text Available This study investigated the spread of MRSA (methicillin-resistant Staphylococcus aureus on two Belgian pig farms. Pigs of different ages (from farrowing to slaughter age and sows as well as the barn environment were screened extensively on two occasions three months apart. A subset of MRSA isolates was tested for antimicrobial susceptibility to 16 antibiotics and was further characterized by pulsed-field gel electrophoresis. Ninety-five percent and 77% of the tested pigs on farm A and farm B, respectively, were colonized with MRSA. MRSA positive animals were detected in all age categories sampled on each sampling day. Piglets were already colonized in the farrowing unit with the same or other MRSA strains than their mother. The prevalence of MRSA colonized pigs increased significantly after weaning and decreased during the fattening period. Pigs carried MRSA mainly in the nares, followed by the perineum and skin and to a lesser degree the rectum. A pig could be contaminated or colonized with different MRSA strains at the same time. The barn environment was also found to be contaminated with different MRSA strains, including the air inlet and outlet. All isolates tested on both farms were resistant to both tetracycline and trimethoprim, while they were susceptible to rifampicin, mupirocin and linezolid. There was a significant difference in resistance prevalence between the two farms for the antibiotics gentamicin, kanamycin, tobramycin, tylosin, lincomycin and quinupristin/dalfopristin. Furthermore, several antibiotic resistance profiles were observed within one farm. This study clearly indicates that several MRSA strains circulate on one farm, from the nursery unit to the fattening unit. This is important to consider when attempts are made to remediate these farms.

  15. EPLAN-pulse; A midterm model for the evaluation of Belgian electricity production

    Energy Technology Data Exchange (ETDEWEB)

    Lissens, G. (VITO, Energy division, Mol (Belgium))

    1993-01-01

    The model presented, EPLAN, simulates the electricity production system in Belgium, the relevant decision making processes, investments in new generating capacity, the emissions of power plants (NO[sub x], SO[sub 2], particles, gypsum and nuclear waste), the costs of the system and its fuel use. The model in its present state is developed around a core model of the University of Antwerp to evaluate capacity planning of the Belgian electricity producers, and has been enhanced in many ways at VITO, the Flemish Institute for Technological Research. It should be made clear from the start that emission forecasts in the electricity sector are not eligible for trend extrapolation or other statistical methods on their own. Data on production and emissions of the electricity sector between 1980 and 1990 show an increase in production of electricity of some 30%, while emissions of SO[sub 2] went down by more than 70% and emission of NO[sub x] declined by more than 30%, which is illustrative for the previous statement. The dependency of emissions on technology make that emission forecasting in the electricity sector cannot be done by models other than those which take into account each technology that is eligible for investment over the specified time horizon. Combining technological parameters with social, environmental and economic principles is what EPLAN is supposed to do. Much of its merits are thus attributable to the expertise of the developer of the social, technological, environmental and economic scenarios, for which EPLAN allows full flexibility. Fuel price scenarios, demand scenarios, efficiencies of every single production unit, type of demand curve, efficiency of emission reduction technologies, and many more are easy to define and it takes only very little time for an experienced EPLAN-operator to install a completely new scenario or add a new technology. (au).

  16. Laboratory corrosion tests on candidate high-level waste container materials: Results from the Belgian programme

    International Nuclear Information System (INIS)

    The Belgian SAFIR-2 concept foresees the geological disposal of conditioned high-level radioactive waste in stainless steel containers and overpacks placed in a concrete gallery backfilled with Boom clay or a bentonite-type backfill. In addition to earlier in situ experiments, we used a laboratory approach to investigate the corrosion properties of selected stainless steels in Boom clay and bentonite environments. In the SAFIR-2 concept, AISI 316L hMo is the main candidate overpack material. As an alternative, we also investigated the higher alloyed stainless steel UHB 904L. Our study focused on localised corrosion and in particular pitting. We used cyclic potentiodynamic polarisation measurements to determine the pit nucleation potential ENP and the protection potential EPP. The evolution of the corrosion potential with time was determined by monitoring the open circuit potential in synthetic clay-water over extended periods. In this paper we present and discuss some results from our laboratory programme, focusing on long-term interactions between the stainless steel overpack and the backfill materials. We describe in particular the influence of chloride and thio-sulphate ions on the pitting corrosion behaviour. The results show that, under geochemical conditions typical for geological disposal, i.e. [Cl-] ∼ 30 mg/L for a Boom clay backfill and [Cl-] ∼ 90 mg/L for a bentonite backfill, neither AISI 316L hMo nor UHB 904L is expected to present pitting problems. An important factor in the long-term prediction of the corrosion behaviour however, is the robustness of the model for the evolution of the geochemistry of the backfill. Indeed, at chloride levels higher than 1000 mg/L, we predict pitting corrosion for AISI 316L hMo. (authors)

  17. Multiyear Serological Surveillance of Notifiable Influenza A Viruses in Belgian Poultry: A Retrospective Analysis.

    Science.gov (United States)

    Marché, Sylvie; Houdart, Philippe; van den Berg, Thierry; Lambrecht, Bénédicte

    2015-12-01

    Surveillance of notifiable avian influenza (NAI) virus is mandatory in European member states, and each year a serological survey is performed to detect H5 and H7 circulation in poultry holdings. In Belgium, this serological monitoring is a combination of a stratified and a risk-based approach and is applied to commercial holdings with more than 200 birds. Moreover, a competitive nucleoprotein (NP) ELISA has been used as first screening method since 2010. A retrospective analysis of the serological monitoring performed from 2007 through 2013 showed sporadic circulation of notifiable low-pathogenicity avian influenza (LPAI) viruses in Belgian holdings with a fluctuating apparent flock seroprevalence according to years and species. Overall, the highest apparent flock seroprevalence was detected for the H5 subtype in domestic Anatidae, with 20%-50% for breeding geese and 4%-9% for fattening ducks. Positive serology against non-H5/H7 viruses was also observed in the same species with the use of the IDScreen influenza A antibody competition ELISA kit (ID-vet NP ELISA), and confirmed by isolation of H2, H3, H6, and H9 LPAI viruses. Among Galliformes, the apparent flock seroprevalence was lower, ranging between 0.3% and 1.3%. Circulation of notifiable LPAI viruses was only observed in laying hens with a similar seroprevalence for H5 and H7. Based on ID-vet NP ELISA results, no circulation of LPAI viruses, regardless the subtype, was observed in breeding chickens and fattening turkeys. Retrospectively, the use of an ELISA as first-line test not only reduced the number of hemagglutination inhibition tests to be performed, but also gave a broader evaluation of the prevalence of LPAI viruses in general, and might help to identify the most at-risk farms. PMID:26629630

  18. Belgian experience in applying the {open_quotes}leak-before-break{close_quotes} concept to the primary loop piping

    Energy Technology Data Exchange (ETDEWEB)

    Gerard, R.; Malekian, C.; Meessen, O. [Tractebel Energy Engineering, Brussels (Belgium)

    1997-04-01

    The Leak Before Break (LBB) concept allows to eliminate from the design basis the double-ended guillotine break of the primary loop piping, provided it can be demonstrated by a fracture mechanics analysis that a through-wall flaw, of a size giving rise to a leakage still well detectable by the plant leak detection systems, remains stable even under accident conditions (including the Safe Shutdown Earthquake (SSE)). This concept was successfully applied to the primary loop piping of several Belgian Pressurized Water Reactor (PWR) units, operated by the Utility Electrabel. One of the main benefits is to permit justification of supports in the primary loop and justification of the integrity of the reactor pressure vessel and internals in case of a Loss Of Coolant Accident (LOCA) in stretch-out conditions. For two of the Belgian PWR units, the LBB approach also made it possible to reduce the number of large hydraulic snubbers installed on the primary coolant pumps. Last but not least, the LBB concept also facilitates the steam generator replacement operations, by eliminating the need for some pipe whip restraints located close to the steam generator. In addition to the U.S. regulatory requirements, the Belgian safety authorities impose additional requirements which are described in details in a separate paper. An novel aspect of the studies performed in Belgium is the way in which residual loads in the primary loop are taken into account. Such loads may result from displacements imposed to close the primary loop in a steam generator replacement operation, especially when it is performed using the {open_quote}two cuts{close_quotes} technique. The influence of such residual loads on the LBB margins is discussed in details and typical results are presented.

  19. Geriatric day hospital: opportunity or threat? A qualitative exploratory study of the referral behaviour of Belgian general practitioners

    Directory of Open Access Journals (Sweden)

    Vyncke Veerle

    2010-07-01

    Full Text Available Abstract Background In order to address the challenges of an ageing population the Belgian government decided to allocate resources to the creation of geriatric day hospitals (GDHs. Although GDHs are meant to be a strategy to support general practitioners (GPs caring for the frail elderly, few Belgian GPs seem to refer to a GDH. This study aims to explore the barriers and facilitating factors of GPs' referral to GDHs. Methods A qualitative study using focus group discussions (FGDs was conducted. Fifteen FGDs were organized in the different Belgian regions (Flanders, Wallonia, Brussels. Results Contextual factors such as the unsatisfactory cooperation between hospital and GPs and organizational barriers such as the lack of communication on referral procedures between hospital and primary health care (PHC were identified. Lack of basic knowledge about the concept or the local organization of GDH seemed to be a problem. Unclear task descriptions, responsibilities and activities of a GDH formed prominent points of discussion in all FGDs. Nevertheless a lot of possible advantages and disadvantages of GDHs for the patient and for the GP were mentioned. Conclusions In the case of poor referral to GDHs, focusing on improving overall collaboration between primary and secondary health care is essential. This can be achieved by actively delivering adequate information, permanent communication and more involvement of PHC in the organization and functioning of GDHs. The absence of a transparent health care system with delineated role definitions, seems to hinder the integration of new initiatives like GDHs in the care process. Strategies to enhance referral to GDHs should use a comprehensive approach.

  20. PM2.5 and NOx from traffic: human health impacts, external costs and policy implications from the Belgian perspective

    OpenAIRE

    Michiels, Hans; Mayeres, Inge; Int Panis, Luc; De Nocker, Luc; DEUTSCH Felix; Lefebvre, Wouter

    2012-01-01

    This article employs an optimized impact pathway approach to marginal external health costs that relies on high-resolution dispersion models calibrated for Belgium and the surrounding areas. Per tonne, the MEHC PM2.5 is found to be many times larger than MEHC NOx, which is currently negative. Further, the impact of Belgian PM2.5 emissions in the immediate area of generation is significantly larger than the impact on more distant areas; the opposite is true for NOx. The MEHCs of both pollutant...

  1. PLIM. Overview of the Belgian situation in an international framework; PLIM. Overzicht van het Belgisch gebeuren in een internationaal kader

    Energy Technology Data Exchange (ETDEWEB)

    Van de Velde, J.; Van Wale, E.; Arien, B.; Decreton, M.; Vankeerberghen, M

    1998-09-01

    Plant Life Management (PLIM) is discussed from an international perspective. PLIM consists in the management of a system technology for the exploitation of nuclear power plants taking into account a number of criteria including the design specifications of a nuclear power plant; the operational follow-up of structures, systems, components and human resources; the socio-political climate; the economic relevance. Terminology and various aspects related to the life time of nuclear power plants are discussed. PLIM approaches in different countries are described and the role of international organisations with respect to PLIM are discussed. Special emphasis is on the Belgian context.

  2. Microstructured optical fiber Bragg grating-based strain and temperature sensing in the concrete buffer of the Belgian supercontainer concept

    Science.gov (United States)

    Geernaert, Thomas; Sulejmani, Sanne; Sonnenfeld, Camille; Luyckx, Geert; Chah, Karima; Areias, Lou; Mergo, Pawel; Urbanczyk, Waclaw; Van Marcke, Philippe; Coppens, Erik; Thienpont, Hugo; Berghmans, Francis

    2014-05-01

    We present the use of microstructured optical fiber Bragg grating-based sensors for strain and temperature monitoring inside the concrete buffer of the Belgian supercontainer concept, demonstrated in a half-scale test in 2013. This test incorporated several optical fiber sensors inside the concrete buffer for production and condition monitoring. The optical fiber sensors presented here consist of small carbon-reinforced composite plates in which highly birefringent Butterfly microstructured optical fibers, equipped with fiber Bragg gratings, were embedded. The double reflection spectrum of these MOFGBs allows to simultaneously monitor strain and temperature, as confirmed by comparison with data obtained from thermocouples and vibrating-wire sensors installed near the MOFBGs.

  3. An Explorative Mapping of the Belgian Social Media Marketing Value Network and Its Usage of Personal Identifiable Information

    OpenAIRE

    Heyman, Rob; Pierson, Jo

    2014-01-01

    Research has shown an increase in both disclosure of personal data and means to gather this data on social media such as Facebook. Little research has been done to analyze what happens with this data and how it circulates between different actors. The aim of this research is to map a subset of the Belgian social media marketing companies as a value network and how these actors use social media users’ data for marketing campaigns. The answer to this research question was obtained through exper...

  4. Inventory and forecasting of maritime emissions in the Belgian sea territory, an activity-based emission model

    OpenAIRE

    Schrooten, Liesbeth; De Vlleger, Ina; Panis, Luc Int; Styns, Karel; TORFS, Rudi

    2008-01-01

    Air quality policy has focussed on land-based emissions for decades. In recent years, it has become increasingly clear that emissions from sea-going vessels can no longer be ignored. There is a growing need for detailed emission inventories to evaluate the impact of this transport mode on air quality and health.In this paper we present MOPSEA, an activity-based emission model to determine emissions from sea-going vessels. The model considers shipping activities of sea-going vessels on Belgian...

  5. Assessment of management alternatives for LWR wastes. Volume 4. Description of a Belgian scenario for PWR waste

    International Nuclear Information System (INIS)

    This report deals with the description of a management route for PWR waste relying to a certain extent on Belgian practices in this particular area. This description, which aims at providing input data for subsequent cost evaluation, includes all management steps which are usually implemented for solid, liquid and gaseous wastes from their production up to the interim storage of the final waste products. This study is part of an overall theoretical exercise aimed at evaluating a selection of management routes for LWR waste based on economical and radiological criteria

  6. More than just water - Planning scenarios for a sustainable development of the Belgian part of the North Sea

    OpenAIRE

    Vanden Abeele, Peter

    2005-01-01

    Although the sea is one of the most decisive factors for the planning of any coastal region, Belgian planners and policymakers have been doing it with their back towards the sea. But in the face of new spatial claims for more marine transport, windmill farms, sand and gravel extraction, and even nature conservation, policymakers are forced to rethink the role of this seemingly endless surface of water. In the future this role will become even more important as the sea level will rise due to c...

  7. Rationale, design, and baseline findings from HIPP: A randomized controlled trial testing a home-based, individually-tailored physical activity print intervention for African American women in the Deep South.

    Science.gov (United States)

    Pekmezi, Dori; Ainsworth, Cole; Joseph, Rodney; Bray, Molly S; Kvale, Elizabeth; Isaac, Shiney; Desmond, Renee; Meneses, Karen; Marcus, Bess; Demark-Wahnefried, Wendy

    2016-03-01

    African American women report high rates of physical inactivity and related health disparities. In our previous formative research, we conducted a series of qualitative assessments to examine physical activity barriers and intervention preferences among African American women in the Deep South. These data were used to inform a 12-month Home-based, Individually-tailored Physical activity Print (HIPP) intervention, which is currently being evaluated against a wellness contact control condition among 84 post-menopausal African American women residing in the metropolitan area of Birmingham, Alabama. This paper reports the rationale, design and baseline findings of the HIPP trial. The accrued participants had an average age of 57 (SD=4.7), a BMI of 32.1kg/m(2) (SD=5.16) with more than half (55%) having a college education and an annual household income under $50,000 (53.6%). At baseline, participants reported an average of 41.5min/week (SD=49.7) of moderate intensity physical activity, and 94.1% were in the contemplation or preparation stages of readiness for physical activity. While social support for exercise from friends and family was low, baseline levels of self-efficacy, cognitive and behavioral processes of change, decisional balance, outcome expectations, and enjoyment appeared promising. Baseline data indicated high rates of obesity and low levels of physical activity, providing strong evidence of need for intervention. Moreover, scores on psychosocial measures suggested that such efforts may be well received. This line of research in technology-based approaches for promoting physical activity in African American women in the Deep South has great potential to address health disparities and impact public health. PMID:26944022

  8. Grandma plays favourites: X-chromosome relatedness and sex-specific childhood mortality †

    OpenAIRE

    Fox, Molly; Sear, Rebecca; Beise, Jan; Ragsdale, Gillian; Voland, Eckart; Knapp, Leslie A.

    2009-01-01

    Biologists use genetic relatedness between family members to explain the evolution of many behavioural and developmental traits in humans, including altruism, kin investment and longevity. Women's post-menopausal longevity in particular is linked to genetic relatedness between family members. According to the ‘grandmother hypothesis’, post-menopausal women can increase their genetic contribution to future generations by increasing the survivorship of their grandchildren. While some demographi...

  9. Women's Work.

    Science.gov (United States)

    Rubin, Vera

    1986-01-01

    Provides an historic overview of the conditions and obstacles encountered by women in pursuing careers in astronomy. Highlights the accomplishments and contributions made by successful women in the field. Reviews the current status and climate associated with women in astronomy and the sciences in general. (ML)

  10. Analysis of the particular spill characteristics observed by the Belgian aerial surveillance program during the Tricolor incident

    International Nuclear Information System (INIS)

    This presentation described the Tricolor oil spill incident, the remote sensing equipment used to monitor the spill, the observed spill characteristics and the flight data assessment. The spill occurred on December 14, 2002 following a collision between the carrier Tricolor and the container vessel Kariba in French waters in the Zone of Joint Responsibility, close to the Belgian and English borders. The Tricolor sank and 3 more vessels collided with the wreck in the five weeks following the collision, spilling several 100 tons of mostly heavy fuel oil into the sea. The remote sensing equipment aboard Belgian surveillance aircraft noted that freshly spilled oil formed a network of widespread dark oil trails surrounded by light oil fractions. The spill volumes were estimated to be high because of the large extent of the polluted area. Nine months following the spill, the emulsified oil trails had a density close to that of seawater. It was assumed that a cold and thick emulsion had formed and became trapped inside the wreck. Upon release, the emulsion could submerse and resurface. The incident demonstrated that early stage oil sample analysis could help interpret slick behaviour by means of remote sensing. 9 refs., 3 tabs., 1 fig

  11. Obesity or overweight is associated with worse pathological response to neoadjuvant chemotherapy among Chinese women with breast cancer.

    Directory of Open Access Journals (Sweden)

    Sheng Chen

    Full Text Available BACKGROUND: To evaluate the relationship between body mass index (BMI and response to neoadjuvant chemotherapy (NCT for breast cancer among Chinese women. PATIENTS AND METHODS: A total of 307 eligible patients were assigned to receive four cycles of paclitaxel and carboplatin before standard surgery for breast cancer from 2007 to 2011 at Shanghai Cancer Hospital. The patients were categorized as obese, overweight, normal weight, or underweight based on BMI according to World Health Organization (WHO criteria. Pathological complete response (pCR was defined as no invasive cancer in the breast or axillary tissue. A logistic regression and the Chi-squared test were used for detecting the predictors of pCR and determining the relationship between BMI category and pCR rate in the subgroup analysis with respect to other variables. RESULTS: Categorical BMI, estrogen receptor (ER, and progesterone receptor (PR status were independent predictors of pCR according to the multivariate analysis. Patients with BMI≥25 were less likely to achieve a pCR to NCT compared with patients with BMI<25 (Odds ratio: 0.454, p = 0.033, multivariate analysis. In the subgroup analysis, the predictive value of BMI for pCR to NCT was significantly shown in post-menopausal patients (p = 0.004 and hormonal receptor status-negative patients (p = 0.038. The incidence of treatment-induced toxicity was similar among the different BMI categories. CONCLUSION: Higher BMI was associated with worse pCR to NCT. Further approaches to investigating the mechanism of this influence of BMI on treatment response and a more appropriate schedule for calculating NCT dose for high-BMI-patients should be considered.

  12. HIV positive asylum seekers receiving the order to leave the Belgian territory

    Directory of Open Access Journals (Sweden)

    Remy Demeester

    2014-11-01

    Full Text Available Introduction: In a human rights based approach, the Parliamentary Assembly of the Council of Europe has recently released a resolution about migrants and refugees and the fight against HIV (1. It states that “an HIV positive migrant should never be expelled when it is clear that he will not receive adequate health care and assistance in the country to which he is being sent back. To do otherwise would amount to a death sentence for that person.” Nevertheless, in Belgium, for the last 2 years, none of the HIV-infected migrants in care in the AIDS Reference Centers (ARC received the right to stay in Belgium for medical reasons. Methods: We identified all HIV-infected asylum seekers in care between 1 July 2012 and 1 July 2014 in the ARC of Charleroi, Belgium, and we analyzed their medical and social files. Results: Among the 302 patients in active follow up in our ARC, 45 HIV positive asylum seekers were in care during the last 2 years. Male/female ratio was 0/96. Mean age was 35 years. Countries of origin and reasons for migration are detailed in the Table 1. 18% (8/45 knew their seropositivity before arriving in Europe. All the patients introduced an asylum request, 29 (64% have received a negative answer and an order to leave the territory, 4 (9% were regularized for non-medical reasons (see Table 1, 4 (9% are waiting for an answer and for 8 (18% outcome is unknown due to lost follow up (LFU. 31 (69% patients have also introduced a request to stay for medical reasons: 18 (58% have received a refusal, 7 (23% are still waiting for an answer, and 6 (19% are LFU. Only 23 (51% patients are still in care in our ARC on 1 July 2014 (see Table 1. The immigration office bases its decisions on availability of the treatment in the country even if accessible only to a limited number of patients. Conclusions: Decisions taken by the Belgian authorities for the last two years concerning HIV-infected asylum seekers do not guarantee the continuity of care of

  13. The attitude of Belgian social insurance physicians towards evidence-based practice and clinical practice guidelines

    Directory of Open Access Journals (Sweden)

    Aertgeerts Bert

    2009-09-01

    Full Text Available Abstract Background Evidence-based medicine has broadened its scope and is starting to reach insurance medicine. Although still in its initial stages, physicians in the area of insurance medicine should keep up-to-date with the evidence on various diseases in order to correctly assess disability and to give appropriate advice about health care reimbursement. In order to explore future opportunities of evidence-based medicine to improve daily insurance medicine, there is a need for qualitative studies to better understand insurance physicians' perceptions of EBM. The present study was designed to identify the attitude of insurance physicians towards evidence-based medicine and clinical practice guidelines, and to determine their ability to access, retrieve and appraise the health evidence and the barriers for applying evidence to practice. Methods A cross-sectional survey study was carried out among all Dutch-speaking insurance physicians employed at one of the six Belgian social insurance sickness funds and at the National Institute of Disability and Health care Insurance (n = 224. Chi-square tests were used to compare nominal and ordinal variables. Student's t-tests, ANOVA, Mann-Whitney and Kruskal-Wallis were used to compare means of continuous variables for different groups. Results The response rate was 48.7%. The majority of respondents were positive towards evidence-based medicine and clinical practice guidelines. Their knowledge of EBM was rather poor. Perceived barriers for applying evidence to practice were mainly time and lack of EBM skills. Conclusion Although the majority of physicians were positive towards EBM and welcomed more guidelines, the use of evidence and clinical practice guidelines in insurance medicine is low at present. It is in the first place important to eradicate the perceived inertia which limits the use of EBM and to further investigate the EBM principles in the context of insurance medicine. Available high

  14. Microbiota characterization of a Belgian protected designation of origin cheese, Herve cheese, using metagenomic analysis.

    Science.gov (United States)

    Delcenserie, V; Taminiau, B; Delhalle, L; Nezer, C; Doyen, P; Crevecoeur, S; Roussey, D; Korsak, N; Daube, G

    2014-10-01

    Herve cheese is a Belgian soft cheese with a washed rind, and is made from raw or pasteurized milk. The specific microbiota of this cheese has never previously been fully explored and the use of raw or pasteurized milk in addition to starters is assumed to affect the microbiota of the rind and the heart. The aim of the study was to analyze the bacterial microbiota of Herve cheese using classical microbiology and a metagenomic approach based on 16S ribosomal DNA pyrosequencing. Using classical microbiology, the total counts of bacteria were comparable for the 11 samples of tested raw and pasteurized milk cheeses, reaching almost 8 log cfu/g. Using the metagenomic approach, 207 different phylotypes were identified. The rind of both the raw and pasteurized milk cheeses was found to be highly diversified. However, 96.3 and 97.9% of the total microbiota of the raw milk and pasteurized cheese rind, respectively, were composed of species present in both types of cheese, such as Corynebacterium casei, Psychrobacter spp., Lactococcus lactis ssp. cremoris, Staphylococcus equorum, Vagococcus salmoninarum, and other species present at levels below 5%. Brevibacterium linens were present at low levels (0.5 and 1.6%, respectively) on the rind of both the raw and the pasteurized milk cheeses, even though this bacterium had been inoculated during the manufacturing process. Interestingly, Psychroflexus casei, also described as giving a red smear to Raclette-type cheese, was identified in small proportions in the composition of the rind of both the raw and pasteurized milk cheeses (0.17 and 0.5%, respectively). In the heart of the cheeses, the common species of bacteria reached more than 99%. The main species identified were Lactococcus lactis ssp. cremoris, Psychrobacter spp., and Staphylococcus equorum ssp. equorum. Interestingly, 93 phylotypes were present only in the raw milk cheeses and 29 only in the pasteurized milk cheeses, showing the high diversity of the microbiota

  15. "Belgian black and red marbles" as potential candidates for Global Heritage Stone Resource

    Science.gov (United States)

    Tourneur, Francis; Pereira, Dolores

    2016-04-01

    The Paleozoic substrate of South Belgium is rich in compact limestones, able to take a good polished finishing and to be used as "marbles". Among them, the black and red varieties were and still are of special importance, intensively exploited and largely exported, almost worldwide. The pure black marbles were extracted mostly from Frasnian (Upper Devonian) and Viséan (Lower Carboniferous) strata, in many localities like Namur, Dinant, Theux and Basècles. Today only the Frasnian variety is still exploited in a spectacular underground quarry in Golzinne, close to the town of Gembloux. These black marbles, already known in Antiquity, were exported since the Middle Age, first in Western Europe, then, from the 19th c., at a larger scale, almost worldwide. Among their most frequent uses figured of course funeral objects, like the epitaph of the Pope Adrian the 1st, offered by Charlemagne and preserved in the St-Pieter basilica in Rom. Another famous reference is the tombs of the Dukes of Burgundy in Dijon, with white crystalline marble and alabaster. The red marbles are limestones from reefal origin, forming mudmounds more or less rich in fossils of Late Frasnian (Late Devonian) age. They show a strong variability in colors, from dark red to light pinkish grey, and in texture, with many sedimentary structures and/or tectonic veins. The outcrops are non-stratified, which allows extraction of large blocks, for example for high columns. Known in the Roman time, they were intensively exploited since at least the 16th c. During the 19th and beginning of 20th c., more than hundred quarries were active in South Belgium, from Rance at West to Chaudfontaine at East, around Philippeville and Rochefort. They were largely used both in civil and religious buildings, mostly for inside decoration, for examples as altars or fireplaces. Among the most symbolic places, the Belgian red marbles were massively employed in Versailles, like in the famous "Galerie des Glaces". But many

  16. Manifestations of somatic disturbances in early postmenopause in women after physiological and surgical menopause

    Directory of Open Access Journals (Sweden)

    Ninčić Dejan

    2006-01-01

    hyperlipoproteinemia. The frequency of somatic signs in early post menopause is typically higher after induced menopause. More intensive follow-up in patients after surgical removing of the ovaria is necessary in order to improve the quality of life in these patients.

  17. The role of Callionymus lyra (L.) and C. reticulatus in the life cycle of Lernaeocera lusci in Belgian coastal waters (Southern Bight of the North Sea)

    NARCIS (Netherlands)

    Van Damme, P.A.; Maertens, D.; Arrumm, A.; Hamerlynck, O.; Ollevier, F.

    1993-01-01

    A survey of the dragonet Callionymus lyra and the reticulated dragonet C. reticulatus from Belgian coastal waters (Southern Bight of the North Sea) in June 1991 revealed 34% of dragonets infected with 1–7 Lernaeocera lusci. This same parasite infected 9% of the reticulated dragonets (mean intensity

  18. Comparison of external morphological traits of newborns to inner morpholical traits of the dam in the double-muscled Belgian Blue Beef breed.

    NARCIS (Netherlands)

    Coopman, F.; Gengler, N.; Groen, A.F.; Smet, de S.; Zeveren, van A.

    2004-01-01

    In the double-muscled (DM) Belgian Blue Beef (BBB) breed, caesarean section (CS) is used as a routine management tool to prevent dystocia. This practice is criticized on animal welfare grounds. With unassisted (natural) births, difficulties arise because of disproportion between the sizes of the new

  19. The Five-Factor Personality Inventory as a Measure of the Five-Factor Model: Belgian, American, and Hungarian Comparisons with the NEO-PI-R

    Science.gov (United States)

    De Fruyt, Filip; McCrae, Robert R.; Szirmak, Zsofia; Nagy, Janos

    2004-01-01

    The lexically based Five-Factor Personality Inventory (FFPI) was correlated with the factors and facets of the Revised NEO Personality Inventory (NEO-PI-R) in Belgian (N = 265), American (N = 116), and Hungarian (N = 320) samples. Results were similar across the three cultures. Analysis of orthogonalized FFPI factors showed that three of…

  20. European Influences in Spanish Popular Education: The Case of the Socialist "Casa Del Pueblo" of Madrid and the Belgian Model (1897-1929)

    Science.gov (United States)

    Guerena, Jean-Louis

    2006-01-01

    In Spain from the late nineteenth century, the "People's Houses" (Casas del Pueblo) corresponded to a desire to provide and organize a space of sociability for workers and their families. This formed part of the diverse Spanish popular education movement. This article focuses on the project to translate the model of the Belgian Maison du Peuple…

  1. High resolution mapping of the tropospheric NO2 distribution in three Belgian cities based on airborne APEX remote sensing

    Science.gov (United States)

    Tack, Frederik; Merlaud, Alexis; Fayt, Caroline; Danckaert, Thomas; Iordache, Daniel; Meuleman, Koen; Deutsch, Felix; Adriaenssens, Sandy; Fierens, Frans; Van Roozendael, Michel

    2015-04-01

    An approach is presented to retrieve tropospheric nitrogen dioxide (NO2) vertical column densities (VCDs) and to map the NO2 two dimensional distribution at high resolution, based on Airborne Prism EXperiment (APEX) observations. APEX, developed by a Swiss-Belgian consortium on behalf of ESA (European Space Agency), is a pushbroom hyperspectral imager with a high spatial (approximately 3 m at 5000 m ASL), spectral (413 to 2421 nm in 533 narrow, contiguous spectral bands) and radiometric (14-bit) resolution. VCDs are derived, following a similar approach as described in the pioneering work of Popp et al. (2012), based on (1) spectral calibration and spatial binning of the observed radiance spectra in order to improve the spectral resolution and signal-to-noise ratio, (2) Differential Optical Absorption Spectroscopy (DOAS) analysis of the pre-processed spectra in the visible wavelength region, with a reference spectrum containing low NO2 absorption, in order to quantify the abundance of NO2 along the light path, based on its molecular absorption structures and (3) radiative transfer modeling for air mass factor calculation in order to convert slant to vertical columns. This study will be done in the framework of the BUMBA (Belgian Urban NO2 Monitoring Based on APEX hyperspectral data) project. Dedicated flights with APEX mounted in a Dornier DO-228 airplane, operated by Deutsches Zentrum für Luft- und Raumfahrt (DLR), are planned to be performed in Spring 2015 above the three largest and most heavily polluted Belgian cities, i.e. Brussels, Antwerp and Liège. The retrieved VCDs will be validated by comparison with correlative ground-based and car-based DOAS observations. Main objectives are (1) to assess the operational capabilities of APEX to map the NO2 field over an urban area at high spatial and spectral resolution in a relatively short time and cost-effective way, and to characterise all aspects of the retrieval approach; (2) to use the APEX NO2 measurements

  2. Women and Diabetes

    Medline Plus

    Full Text Available ... Consumer Information by Audience For Women Women's Health Topics Women and Diabetes Share Tweet Linkedin Pin it ... Depression in Older Women More in Women's Health Topics Mammography Women and Diabetes HPV, HIV, Birth Control ...

  3. BeTemper: thermal characterisation of the Belgian subsoil for shallow geothermal applications

    Science.gov (United States)

    Petitclerc, Estelle; Dusar, Michiel; Declercq, Pierre-Yves; Vanbrabant, Yves

    2015-04-01

    -ray Diffraction equipment, while the EDS (Energy-Dispersive X-ray Spectroscopy) and EBSD (Electron BackScattered Diffraction) modules is applied in order to evaluate the chemical and micro-textural content. Special attention is given to lithologies having a variable λ values to assess the influence of porosity and/or minor mineralogical phases on the heat transfer. The sample selection is conducted in order to be representative of the various lithologies composing the Belgian subsoil, taking into account their mineralogical composition, petrological texture along with their degree of alteration. A special emphasis is given to densely populated areas (eg. Sambre & Meuse valleys and large cities of Flanders). with the highest geothermal demands. Petitclerc, E., Dusar, M., Declercq, P-Y., Hoes, H., Laenen, B., Dagrain,F., Vanbrabant, Y., 2013. Overview and perspectives on shallow geothermal energy in Belgium. Proceedings SG6-12, EGC2013, Pisa, June 2013. Popov, Y., Bayuk, I., Parshin, A., Miklashevskiy, D., Novikov, S., Chekhonin, E., 2012. New methods and instruments for determination of reservoir thermal properties. Thirty-Seventh Workshop on Geothermal Reservoir Engineering, Stanford University, Stanford, California, January 30 - February 1, 2012. SGP-TR-194. Popov, Y., Pribnow, D.F.C., Sass, J.H, Williams, C., Burkhardt, H., 1999. Characterization of rock thermal conductivity by high-resolution optical scanning. Geothermics 28, pp 253-276.

  4. Prevalence and origin of HIV-1 group M subtypes among patients attending a Belgian hospital in 1999.

    Science.gov (United States)

    Snoeck, Joke; Van Dooren, Sonia; Van Laethem, Kristel; Derdelinckx, Inge; Van Wijngaerden, Eric; De Clercq, Erik; Vandamme, Anne-Mieke

    2002-04-23

    HIV-1 group M strains are usually subtyped based on gag and/or env gene sequences. In our lab, part of the pol gene sequence was available in order to determine the genotypic anti-HIV drug resistance profile. To estimate the prevalence of the different HIV-1 subtypes in patients visiting the University Hospitals in Leuven in 1999 and for whom a genotypic drug resistance test was needed, we tried to use the pol sequence for subtyping. Recombination was investigated by similarity plots and bootscanning and subtyping was performed by phylogenetic analysis. The overall region spanning the entire protease and 747 nucleotides of the reverse transcriptase proved very suitable for subtyping, although there was a low phylogenetic signal at the beginning of the reverse transcriptase (nucleotides 0-250), as we demonstrated by likelihood mapping. Of the 41 samples analyzed, 21 belonged to subtype B. Of the other 20 non-B strains, 9 belonged to subtype C, 2 to subtype D and 1 to subtype A, G, H and J, respectively, 3 were CRF_02 (Circulating Recombinant Form), 1 was recombinant with a novel breakpoint and 1 sample was untypable. Although subtype B is still the most prevalent subtype in Belgium, it seems to be responsible for only half of the infections in this study. We could also document that the prevalence of subtype C is high in the Belgian native patients, especially among the heterosexually infected population. This could possibly be an indication for an epidemic spread of HIV-1 subtype C in Belgium, as for one third of these patients, no link to an endemic region could be found. The other non-B subtypes and the recombinants are mainly introduced by immigrants or by Belgian citizens traveling abroad. PMID:11955642

  5. Inventory and forecasting of maritime emissions in the Belgian sea territory, an activity-based emission model

    Science.gov (United States)

    Schrooten, Liesbeth; De Vlieger, Ina; Int Panis, Luc; Styns, Karel; Torfs, Rudi

    Air quality policy has focussed on land-based emissions for decades. In recent years, it has become increasingly clear that emissions from sea-going vessels can no longer be ignored. There is a growing need for detailed emission inventories to evaluate the impact of this transport mode on air quality and health. In this paper we present MOPSEA, an activity-based emission model to determine emissions from sea-going vessels. The model considers shipping activities of sea-going vessels on Belgian territory, combined with individual vessel characteristics. We apply this model to study the effects of recent international efforts to reduce emissions from sea-going vessels in Belgian territorial waters for the current fleet and for two scenarios up to 2010. The emission model for Belgium, based on different vessel operating areas, reveals that most maritime emissions from the main engines will increase. CO 2 emissions will increase by 2-9% over the 2004-2010 period due to an increase in shipping activity. NO X emissions are projected to rise between 1% and 8% because the increase in activity offsets the reductions from the international maritime organisation (IMO) and European regulations. In contrast, SO 2 emissions will decrease by at least 50% in 6 years time. The switch of auxiliaries from heavy fuel oil to diesel oil at berth results in a large emission reduction (33%) for PM and small reductions for CO 2, NO X, CO and HC (4-5%). The choice between a bottom-up versus top-down approach can have important implications for the allocation of maritime emissions. The MOPSEA bottom-up model allocates only 0.7 Mton CO 2 to Belgium, compared to 24.2 Mton CO 2 based on bunker fuel inventories.

  6. Sustained use of biogas fuel and blood pressure among women in rural Nepal

    Science.gov (United States)

    Neupane, Maniraj; Basnyat, Buddha; Fischer, Rainald; Froeschl, Guenter; Wolbers, Marcel; Rehfuess, Eva A

    2015-01-01

    Background More than two fifths of the world's population cook with solid fuels and are exposed to household air pollution (HAP). As of now, no studies have assessed whether switching to alternative fuels like biogas could impact cardiovascular health among cooks previously exposed to solid fuel use. Methods We conducted a propensity score matched cross-sectional study to explore if the sustained use of biogas fuel for at least ten years impacts blood pressure among adult female cooks of rural Nepal. We recruited one primary cook ≥30 years of age from each biogas (219 cooks) and firewood (300 cooks) using household and measured their systolic (SBP) and diastolic blood pressure (DBP). Household characteristics, kitchen ventilation and 24-h kitchen carbon monoxide were assessed. We matched cooks by age, body mass index and socio-economic status score using propensity scores and investigated the effect of biogas use through multivariate regression models in two age groups, 30–50 years and >50 years to account for any post-menopausal changes. Results We found substantially reduced 24-h kitchen carbon monoxide levels among biogas-using households. After matching and adjustment for smoking, kitchen characteristics, ventilation status and additional fuel use, the use of biogas was associated with 9.8 mmHg lower SBP [95% confidence interval (CI), −20.4 to 0.8] and 6.5 mmHg lower DBP (95% CI, −12.2 to −0.8) compared to firewood users among women >50 years of age. In this age group, biogas use was also associated with 68% reduced odds [Odds ratio 0.32 (95% CI, 0.14 to 0.71)] of developing hypertension. These effects, however, were not identified in younger women aged 30–50 years. Conclusions Sustained use of biogas for cooking may protect against cardiovascular disease by lowering the risk of high blood pressure, especially DBP, among older female cooks. These findings need to be confirmed in longitudinal or experimental studies. PMID:25460655

  7. Women boxers

    DEFF Research Database (Denmark)

    Gems, Gerald; Pfister, Gertrud Ursula

    2014-01-01

    This article fills a gap in the very limited literature on women's boxing by examining the gendered space in which women engaged in the sport as participants in saloons, vaudeville theatres and the prize ring. In doing so, they challenged the contemporary gender order and disputed the notion of...

  8. Relationship between Carotenoids, Retinol, and Estradiol Levels in Older Women

    Directory of Open Access Journals (Sweden)

    Marcello Maggio

    2015-08-01

    Full Text Available Background. In vitro evidence suggests anti-estrogenic properties for retinol and carotenoids, supporting a chemo-preventive role of these phytochemicals in estrogen-dependent cancers. During aging there are significant reductions in retinol and carotenoid concentrations, whereas estradiol levels decline during menopause and progressively increase from the age of 65. We aimed to investigate the hypothesis of a potential relationship between circulating levels of retinol, carotenoids, and estradiol (E2 in a cohort of late post-menopausal women. Methods. We examined 512 women ≥ 65 years from the InCHIANTI study. Retinol, α-caroten, β-caroten, β-criptoxantin, lutein, zeaxanthin, and lycopene levels were assayed at enrollment (1998–2000 by High-Performance Liquid Chromatography. Estradiol and testosterone (T levels were assessed by Radioimmunometry (RIA and testosterone-to-estradiol ratio (T/E2, as a proxy of aromatase activity, was also calculated. General linear models adjusted for age (Model 1 and further adjusted for other confounders including Body Mass Index (BMI BMI, smoking, intake of energy, lipids, and vitamin A; C-Reactive Protein, insulin, total cholesterol, liver function, and testosterone (Model 2 were used to investigate the relationship between retinol, carotenoids, and E2 levels. To address the independent relationship between carotenoids and E2 levels, factors significantly associated with E2 in Model 2 were also included in a fully adjusted Model 3. Results. After adjustment for age, α-carotene (β ± SE = −0.01 ± 0.004, p = 0.02 and β-carotene (β ± SE = −0.07 ± 0.02, p = 0.0007 were significantly and inversely associated with E2 levels. α-Carotene was also significantly and positively associated with T/E2 ratio (β ± SE = 0.07 ± 0.03, p = 0.01. After adjustment for other confounders (Model 2, the inverse relationship between α-carotene (β ± SE = −1.59 ± 0.61, p = 0.01, β-carotene (β ± SE = −0.29

  9. Substantive representation of the working class in a changing environment. Historical evidence from Belgian Parliament

    OpenAIRE

    Wauters, Bram

    2010-01-01

    The link between descriptive representation (being member of a disadvantaged social group) and substantive representation (defending the interests of that group) continues to be one of the most hotly disputed issues in social sciences. The political representation of social classes in this perspective has long time been neglected in research, as the main focus has been on women and ethnic minorities. It will be argued in this paper that class is still relevant in contemporary society and that...

  10. Clinical Analysis of the Treatment of Vertebroplasty Combined with Chinese Herbs in Menopausal Women with Thoracolumbar Osteoporotic Fractures%椎体成形术结合中药内服治疗女性绝经期胸腰椎骨质疏松性骨折的临床疗效分析

    Institute of Scientific and Technical Information of China (English)

    陈继征; 周瑜博; 董振宇; 吕发明

    2013-01-01

      [目的]探讨椎体成形术(percutaneous vertebroplasty,PVP)结合中药内服在治疗女性绝经期胸腰椎骨质疏松性骨折中疗效。[方法]将72例确诊为绝经期骨质疏松性骨折的患者分为对照组及治疗组。对照组单纯采用PVP,治疗组在对照组基础上加用中药内服治疗。评价并比较两组治疗前、治疗后1个月、治疗后3个月时的活动能力评分(MDS)、视觉模拟评分法( visual analogue scale,VAS)评分及疼痛缓解程度。[结果]治疗组治疗3个月后VAS评分明显低于对照组,差异有统计学意义(P<0.05);组内比较,两组在不同治疗时间(治疗前、治疗1个月后及治疗3个月后)VAS评分均较前明显降低,差异有统计学意义,(P<0.05)。两组在治疗1个月及3个月时的疼痛缓解率及MDS有效率相近,差异无统计学意义(P>0.05)。[结论]PVP结合中药内服能有效缓解绝经期胸腰椎骨质疏松性骨折女性疼痛及恢复活动能力。%[Objective] To investigate the application of Vertebroplasty(percutaneous vertebroplasty, PVP) combined with Chinese Herbs in the treatment of post-menopausal women thoracolumbar osteoporotic fractures.[Methods] From March 2011 to June 2012 in the Orthopedic Center in Traditional Chi-nese Medicine Hospital of Xinjiang Medical University ,72 patients diagnosed with post-menopausal osteoporotic fractures were randomly divided into control group and treatment group, the patients in control group were treated with vertebroplasty treatment, the patients in treatment group were treated with vertebroplasty combined with Chinese Herbs.The treatment was for kidney virtual loss, spleen and kidney deficiency type, spleen and kidney defi-ciency and blood stasis. Before treatment, 1 and 3 months after treatment Visual analogue scale(VAS), the activity scores(MDS) were evaluated and com-pared between the two groups.[Results] After 3 months of treatment VAS scores in

  11. 利用DNA指纹图谱技术对健康女性阴道菌群多样性的分析%Analysis of diversity of vaginal microbiota in healthy Chinese women by using DNAfingerprinting

    Institute of Scientific and Technical Information of China (English)

    肖冰冰; 廖秦平

    2012-01-01

    阴道优势菌种之一.%Objective: To analyze the diversity of healthy women' s vaginal dominant flora in different physiological states with PCR-denaturing gradient gel electrophoresis (PCR-DGGE) , to establish the basis for the future study of lower genital tract infections, and to provide a theoretical basis for the development of vaginal probiotics adapted to Chinese females. Methods; Women who underwent routine gynecologic examinations in Peking University First Hospital from October 2009 to January 2010 were enrolled, including 30 at reproductive age and 30 at post menopause age. Vaginal samples were collected and then total bacterial DNA was extracted. Universal bacterial primers were used to amplify the V3 region of 16S rDNA gene. PCR products were analyzed by denatured gradient gel electrophoresis (DGGE). Featured bands on DGGE were recovered, cloned and sequenced. Alignment with known sequence was made by using Blast on GenBank to identify bacterial strains so as to analyze the diversity of healthy women's vaginal dominant flora in different physiological states. Results; (1) Vaginal flora in healthy Chinese women at their reproductive age were relatively simple, Lactobacillus were the dominant bacteria. Common bacteria included: Lactobacillus crispatus, Lactobacillus iners, and Lactobacillus gasse-ri. While L. iners were the dominant vaginal bacteria that could not be recognized by traditional method. (2) Vaginal bacteria in the women at post menopause age were more complex than in those at reproductive age. Common bacteria included: Lactobacillus iners, Lactobacillus crispatus, Escherichia coli, Streptococcus agalactiae, Streptococcus gallolyticus, Veillonella sp. , Streptococcus intermedius, Streptococcus anginosus, Prevotella sp. , Anaerococcus lactolyticus and Bacteroides fragilis. Conclusion; Based on the DGGE analysis, the most common vaginal bacteria in Chinese healthy women at reproductive age are Lactobacillus crispatus, Lactobacillus iners, and Lactobacillus gasseri. the most

  12. Numerical modelling and hydrochemical characterisation of a fresh-water lens in the Belgian coastal plain

    Science.gov (United States)

    Vandenbohede, A.; Lebbe, L.

    2002-05-01

    The distribution of fresh and salt water in coastal aquifers is influenced by many processes. The influence of aquifer heterogeneity and human interference such as land reclamation is illustrated in the Belgian coastal plain where, around A.D. 1200, the reclamation of a tidally influenced environment was completed. The aquifer, which was filled with salt water, was thereafter freshened. The areal distribution of peat, clay, silt and sand influences the general flow and distribution of fresh and salt water along with the drainage pattern and results in the development of fresh-water lenses. The water quality in and around the fresh-water lenses below an inverted tidal channel ridge is surveyed. The hydrochemical evolution of the fresh water lens is reconstructed, pointing to cation exchange, solution of calcite and the oxidation of organic material as the major chemical reactions. The formation and evolution of the fresh water lens is modelled using a two-dimensional density-dependent solute transport model and the sensitivity of drainage and conductivities are studied. Drainage level mainly influences the depth of the fresh-water lens, whereas the time of formation is mainly influenced by conductivity. Résumé. La répartition de l'eau douce et de l'eau salée dans les aquifères littoraux est influencée par de nombreux mécanismes. L'influence de l'hétérogénéité de l'aquifère et des interférences anthropiques telles que la mise en valeur des terres est illustrée par la plaine côtière belge où, depuis l'an 1200, on a mis en valeur un environnement soumis aux marées. L'aquifère, qui contenait de l'eau salée, contient maintenant de l'eau douce. La distribution spatiale de tourbe, d'argile, de silt et de sable joue un rôle dans l'écoulement général et dans la répartition de l'eau douce et de l'eau salée le long du réseau de drainage et produit des lentilles d'eau douce. La qualité de l'eau dans et autour des lentilles d'eau douce sous une lev

  13. Concordance of Results from Randomized and Observational Analyses within the Same Study: A Re-Analysis of the Women's Health Initiative Limited-Access Dataset.

    Directory of Open Access Journals (Sweden)

    Mark J Bolland

    Full Text Available Observational studies (OS and randomized controlled trials (RCTs often report discordant results. In the Women's Health Initiative Calcium and Vitamin D (WHI CaD RCT, women were randomly assigned to CaD or placebo, but were permitted to use personal calcium and vitamin D supplements, creating a unique opportunity to compare results from randomized and observational analyses within the same study.WHI CaD was a 7-year RCT of 1g calcium/400IU vitamin D daily in 36,282 post-menopausal women. We assessed the effects of CaD on cardiovascular events, death, cancer and fracture in a randomized design- comparing CaD with placebo in 43% of women not using personal calcium or vitamin D supplements- and in a observational design- comparing women in the placebo group (44% using personal calcium and vitamin D supplements with non-users. Incidence was assessed using Cox proportional hazards models, and results from the two study designs deemed concordant if the absolute difference in hazard ratios was ≤0.15. We also compared results from WHI CaD to those from the WHI Observational Study(WHI OS, which used similar methodology for analyses and recruited from the same population.In WHI CaD, for myocardial infarction and stroke, results of unadjusted and 6/8 covariate-controlled observational analyses (age-adjusted, multivariate-adjusted, propensity-adjusted, propensity-matched were not concordant with the randomized design results. For death, hip and total fracture, colorectal and total cancer, unadjusted and covariate-controlled observational results were concordant with randomized results. For breast cancer, unadjusted and age-adjusted observational results were concordant with randomized results, but only 1/3 other covariate-controlled observational results were concordant with randomized results. Multivariate-adjusted results from WHI OS were concordant with randomized WHI CaD results for only 4/8 endpoints.Results of randomized analyses in WHI CaD were

  14. Culture-general and -specific associations of attachment avoidance and anxiety with perceived parental warmth and psychological control among Turk and Belgian adolescents.

    Science.gov (United States)

    Güngör, Derya; Bornstein, Marc H

    2010-10-01

    Both the adolescent peer attachment and perceived parenting style literatures emphasize the role of the quality of the parent-child relationship in children's healthy adjustment beyond the family, but few studies have investigated links between adolescents' peer attachment and perceptions of parenting. We investigate relations of adolescents' perceptions of warmth and psychological control from parents with avoidance and anxiety in attachment to close friends in two contrasting cultures. Altogether, 262 Turk and 263 Belgian youth between 14 and 18 years of age participated. Cross-culturally, attachment avoidance was negatively related to maternal warmth, and attachment anxiety positively related to maternal and paternal control and negatively to paternal warmth. Beyond these general relations, attachment avoidance was associated with paternal psychological control in Belgians but not in Turks. The study provides cross-cultural evidence for specific relations between peer attachment and perceived parenting and suggests a culture-specific pathway for the development of attachment avoidance. PMID:20079527

  15. Assessment of the radiological impact and associated risk to non-human biota from routine liquid discharges of the Belgian nuclear power plants

    International Nuclear Information System (INIS)

    We performed an Environmental Risk Assessment (ERA) to evaluate the impact on non-human biota from liquid radioactive effluents discharged by the Belgian Nuclear Power Plants (NPPs) of Doel and Tihange. A deterministic risk assessment for aquatic and terrestrial ecosystems was performed using the ERICA tool and applying the ERICA screening value of 10 μGy.h-1. The ERA was performed for the radioactive discharge limits and for the actual releases (maxima and averages over the last 10 years, 1999-2008). All ERICA reference organisms were considered and depending on the assessment situation, additional reference organisms were included in the analysis. It can be concluded that the current discharge limits for the Belgian NPPs do not result in significant risks to the aquatic and terrestrial environment and that the actual discharges, which are a fraction of the liquid discharge limits, are unlikely to harm the environment. (authors)

  16. Women's health

    Science.gov (United States)

    ... Nurse midwives This list may not be all-inclusive. References Freund K. Approach to women's health. In: ... Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David ...

  17. Tu Women

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    When honored guests visit, Tu women will block the door and invite them to show their respect by drinking three cups of wine. Only after this ritual can the guests be led indoors and shown to their seats.

  18. Smokefree Women

    Science.gov (United States)

    ... News Most Recent 3 Very Real Dangers of Secondhand Smoke Secondhand smoke is the combination of smoke… Read full story: 3 Very Real Dangers of Secondhand Smoke » share 4 Benefits of Quitting Smoking Many women ...

  19. Women Words

    Institute of Scientific and Technical Information of China (English)

    Yuan Yuan

    2012-01-01

    Jiangyong County,a remote place in central China's Hunan Province,has been gathering more attention due to a strange-looking language passed down exclusively by women for hundreds of years. The language,which is called nushu,or women's script,is said to originate from Chinese square-block characters,but the orthography and pronunciation are quite different from all other branches of Chinese dialects.

  20. Implementation of a program for type 2 diabetes based on the Chronic Care Model in a hospital-centered health care system: 'the Belgian experience'

    OpenAIRE

    Van Royen Paul; Vermeire Etienne; Wens Johan; Nobels Frank; Snauwaert Boris; Feyen Luc; Bastiaens Hilde; Sunaert Patricia; De Maeseneer Jan; De Sutter An; Willems Sara

    2009-01-01

    Abstract Background Most research publications on Chronic Care Model (CCM) implementation originate from organizations or countries with a well-structured primary health care system. Information about efforts made in countries with a less well-organized primary health care system is scarce. In 2003, the Belgian National Institute for Health and Disability Insurance commissioned a pilot study to explore how care for type 2 diabetes patients could be organized in a more efficient way in the Bel...