49 CFR 98.2 - Definitions.

Science.gov (United States)

2010-10-01

... Administration. (5) The National Highway Traffic Safety Administration. (6) The Urban Mass Transportation... 49 Transportation 1 2010-10-01 2010-10-01 false Definitions. 98.2 Section 98.2 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES...

49 CFR 98.1 - Purpose.

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Purpose. 98.1 Section 98.1 Transportation Office of the Secretary of Transportation ENFORCEMENT OF RESTRICTIONS ON POST-EMPLOYMENT ACTIVITIES... administrative enforcement procedures that the Department of Transportation will follow when there is an...

27 CFR 21.98 - Bone oil (Dipple's oil).

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bone oil (Dipple's oil....98 Bone oil (Dipple's oil). (a) Color. The color shall be a deep brown. (b) Distillation range. When... below 90 °C. (c) Pyrrol reaction. Prepare a 1.0 percent solution of bone oil in 95 percent alcohol...

40 CFR 98.344 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... Other Technical Requirements For Weighing and Measuring Devices” NIST Handbook 44 (2009)(incorporated by... Natural Gas by Gas Chromatography (incorporated by reference, see § 98.7). (3) ASTM D1946-90 (Reapproved 2006), Standard Practice for Analysis of Reformed Gas by Gas Chromatography (incorporated by reference...

40 CFR 98.413 - Calculating GHG emissions.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Calculating GHG emissions. 98.413 Section 98.413 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.413 Calculating...

40 CFR 98.416 - Data reporting requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Data reporting requirements. 98.416 Section 98.416 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.416 Data...

40 CFR 98.406 - Data reporting requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Data reporting requirements. 98.406 Section 98.406 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Natural Gas and Natural Gas Liquids § 98.406 Data...

40 CFR 98.38 - Definitions.

Science.gov (United States)

2010-07-01

... Still Gas 0.143 66.72 Kerosene 0.135 75.20 Liquefied petroleum gases (LPG) 0.092 62.98 Propane 0.091 61... GREENHOUSE GAS REPORTING General Stationary Fuel Combustion Sources § 98.38 Definitions. All terms used in... 93.65 Mixed (Industrial sector) 22.35 93.91 Mixed (Electric Power sector) 19.73 94.38 Natural gas mm...

40 CFR 98.412 - GHGs to report.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false GHGs to report. 98.412 Section 98.412 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.412 GHGs to report. You must report...

40 CFR 98.411 - Reporting threshold.

Science.gov (United States)

2010-07-01

...) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.411 Reporting threshold. Any supplier of industrial greenhouse gases who meets the requirements of § 98.2(a)(4) must report GHG...

46 CFR 98.25-65 - Filling density.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Filling density. 98.25-65 Section 98.25-65 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS SPECIAL... § 98.25-65 Filling density. (a) The filling density, or the percent ratio of the liquefied gas that may...

Conditional deletion of CD98hc inhibits osteoclast development

Directory of Open Access Journals (Sweden)

Hideki Tsumura

2016-03-01

Full Text Available The CD98 heavy chain (CD98hc regulates virus-induced cell fusion and monocyte fusion, and is involved in amino acid transportation. Here, we examined the role that CD98hc plays in the formation of osteoclasts using CD98hcflox/floxLysM-cre peritoneal macrophages (CD98hc-defect macrophages. Peritoneal macrophages were stimulated with co-cultured with osteoblasts in the presence of 1,25(OH2 vitamin D3, and thereafter stained with tartrate-resistant acid phosphatase staining solution. The multinucleated osteoclast formation was severely impaired in the peritoneal macrophages isolated from the CD98hc-defect mice compared with those from wild-type mice. CD98hc mediates integrin signaling and amino acid transport through the CD98 light chain (CD98lc. In integrin signaling, suppression of the M-CSF-RANKL-induced phosphorylation of ERK, Akt, JNK and p130Cas were observed at the triggering phase in the CD98h-defect peritoneal macrophages. Moreover, we showed that the general control non-derepressible (GCN pathway, which was activated by amino acid starvation, was induced by the CD98hc-defect peritoneal macrophages stimulated with RANKL. These results indicate that CD98 plays two important roles in osteoclast formation through integrin signaling and amino acid transport.

46 CFR 98.30-11 - Cargo pumps.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo pumps. 98.30-11 Section 98.30-11 Shipping COAST..., ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks § 98.30-11 Cargo pumps. No person may operate a cargo pump to transfer a product to or from a portable tank unless the pump...

36 CFR 9.8 - Use of water.

Science.gov (United States)

2010-07-01

... MANAGEMENT Mining and Mining Claims § 9.8 Use of water. (a) No operator may use for operations any water from... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Use of water. 9.8 Section 9.8... Regional Director. The Regional Director shall not approve a plan of operations requiring the use of water...

Regeneration of 98Mo enriched from waste 99mTc generators

International Nuclear Information System (INIS)

Khujaev, S.; Mirzaeva, N.A.; Ashrapov, U.T.; Berdieva, M.; Nushtaeva, L.B.

2002-01-01

Radioisotope generator of technetium-99m have found widespread application in nuclear medicine for production of sodium pertechnetate solution ( 99m Tc). In technology of radioisotope generator making, which developed in Institute of Nuclear Physics of Uzbekistan Academy of Science the parent radioisotopes of molybdenum-90 are produced with neutron capture reaction of the enriched isotope of molybdenum-98 in nuclear reactor of WWR-SM. The specific activity of 99 Mo is reached to 5.0 Ci/g after activation process of original material ( 98 Mo). The basic mass of the original materials ( 98 Mo) which took for the irradiation is remained inactive. The high cost of enriched 97 Mo to make up necessity of development of method of 98 Mo regeneration with end in view of its recurring in manufacture. In general, the chromatographic type generator are produced in manufacture with aluminium oxide as sorbent for the parent radionuclides. So we studied the description conditions of molybdenum from aluminium oxide phase, its purification from possible accompanying admixtures and production of molybdenum in goods state. The systems: sulphur acid, ammonium and ammonium with hydrogen peroxide have been considered for molybdenum desorption from aluminium oxide phase. The sulphur oxid solution is most optimal medium for molybdenum desorption with concentration 0.5 M and elution rate for this makes up 2.0-2.05 ml/min. The 98 Mo yield makes up not over 87 %. The subsequent purification of the desorption of molybdenum-98 from the possible admixture are realized by using column with tetra-phosphonium alkali. At first , 98 Mo sorption is realized by anion exchange resin, after that sorbate is washing and dispiriting by solution with composition: 1.0 M NH 4 NO 3 +8.0 % NH 4 OH+10 -2 % H 2 O 2 . The 98 Mo yield makes up under 80 %. Further from obtained solution is realized by precipitation of molybdenum-98 in acid medium and separation of sediments from liquid phase, drying if sediments and

14 CFR 61.98 - Flight proficiency.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight proficiency. 61.98 Section 61.98 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN...) Navigation; (viii) Slow flight and stalls; (ix) Emergency operations; and (x) Postflight procedures. (2) For...

The Indigenous World, 1997-98 = El Mundo Indigena, 1997-98.

Science.gov (United States)

Erni, Christian, Ed.

This annual publication (published separately in English and Spanish) examines political, legal, social, environmental, and educational issues concerning indigenous peoples around the world during 1997-98. Part I highlights news events and ongoing situations in specific countries in nine world regions. In the Arctic and North America, these…

42 CFR 460.98 - Service delivery.

Science.gov (United States)

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Service delivery. 460.98 Section 460.98 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED..., national origin, religion, sex, age, sexual orientation, mental or physical disability, or source of...

29 CFR 1910.98 - Effective dates.

Science.gov (United States)

2010-07-01

... 29 Labor 5 2010-07-01 2010-07-01 false Effective dates. 1910.98 Section 1910.98 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... section, if any standard in 41 CFR part 50-204, other than a national consensus standard incorporated by...

46 CFR 98.25-75 - Ventilation.

Science.gov (United States)

2010-10-01

... shall be fitted with efficient natural or mechanical ventilation. (b) Enclosed compartments in which... 46 Shipping 4 2010-10-01 2010-10-01 false Ventilation. 98.25-75 Section 98.25-75 Shipping COAST... Ventilation. (a) All enclosed spaces containing cargo tanks fitted with bottom outlet connections shall be...

50 CFR 665.98 - Management area.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Management area. 665.98 Section 665.98 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION... Management area. The American Samoa fishery management area is the EEZ seaward of the Territory of American...

7 CFR 98.4 - Analytical methods.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Analytical methods. 98.4 Section 98.4 Agriculture....4 Analytical methods. (a) The majority of analytical methods used by the USDA laboratories to perform analyses of meat, meat food products and MRE's are listed as follows: (1) Official Methods of...

46 CFR 98.33-11 - Smoking.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Smoking. 98.33-11 Section 98.33-11 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS SPECIAL CONSTRUCTION, ARRANGEMENT, AND OTHER PROVISIONS FOR CERTAIN DANGEROUS CARGOES IN BULK Portable Tanks for Certain Grade E Combustible Liquids and Other Regulated...

45 CFR 98.34 - Parental rights and responsibilities.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Parental rights and responsibilities. 98.34 Section 98.34 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Parental Rights and Responsibilities § 98.34...

45 CFR 98.65 - Audits and financial reporting.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Audits and financial reporting. 98.65 Section 98... DEVELOPMENT FUND Financial Management § 98.65 Audits and financial reporting. (a) Each Lead Agency shall have... independent standards. (g) The Secretary shall require financial reports as necessary. ...

Nucleoporin Nup98 mediates galectin-3 nuclear-cytoplasmic trafficking

Energy Technology Data Exchange (ETDEWEB)

Funasaka, Tatsuyoshi, E-mail: funasaka@staff.kanazawa-u.ac.jp [Laboratory of Molecular and Cellular Biology, Department of Biology, Faculty of Natural Systems, Institute of Science and Engineering, Kanazawa University, Ishikawa (Japan); Balan, Vitaly; Raz, Avraham [Department of Oncology and Pathology, Karmanos Cancer Institute, Wayne State University, School of Medicine, Detroit, MI (United States); Wong, Richard W., E-mail: rwong@staff.kanazawa-u.ac.jp [Laboratory of Molecular and Cellular Biology, Department of Biology, Faculty of Natural Systems, Institute of Science and Engineering, Kanazawa University, Ishikawa (Japan); Bio-AFM Frontier Research Center, Kanazawa Kanazawa University, Ishikawa (Japan)

2013-04-26

Highlights: •Nuclear pore protein Nup98 is a novel binding partner of galectin-3. •Nup98 transports galectin-3 into cytoplasm. •Nup98 depletion leads to galectin-3 nuclear transport and induces growth retardation. •Nup98 may involve in ß-catenin pathway through interaction with galectin-3. -- Abstract: Nucleoporin Nup98 is a component of the nuclear pore complex, and is important in transport across the nuclear pore. Many studies implicate nucleoporin in cancer progression, but no direct mechanistic studies of its effect in cancer have been reported. We show here that Nup98 specifically regulates nucleus–cytoplasm transport of galectin-3, which is a ß-galactoside-binding protein that affects adhesion, migration, and cancer progression, and controls cell growth through the ß-catenin signaling pathway in cancer cells. Nup98 interacted with galectin-3 on the nuclear membrane, and promoted galectin-3 cytoplasmic translocation whereas other nucleoporins did not show these functions. Inversely, silencing of Nup98 expression by siRNA technique localized galectin-3 to the nucleus and retarded cell growth, which was rescued by Nup98 transfection. In addition, Nup98 RNA interference significantly suppressed downstream mRNA expression in the ß-catenin pathway, such as cyclin D1 and FRA-1, while nuclear galectin-3 binds to ß-catenin to inhibit transcriptional activity. Reduced expression of ß-catenin target genes is consistent with the Nup98 reduction and the galectin-3–nucleus translocation rate. Overall, the results show Nup98’s involvement in nuclear–cytoplasm translocation of galectin-3 and ß-catenin signaling pathway in regulating cell proliferation, and the results depicted here suggest a novel therapeutic target/modality for cancers.

Confirmatory Factor Analysis of the Delirium Rating Scale Revised-98 (DRS-R98).

Science.gov (United States)

Thurber, Steven; Kishi, Yasuhiro; Trzepacz, Paula T; Franco, Jose G; Meagher, David J; Lee, Yanghyun; Kim, Jeong-Lan; Furlanetto, Leticia M; Negreiros, Daniel; Huang, Ming-Chyi; Chen, Chun-Hsin; Kean, Jacob; Leonard, Maeve

2015-01-01

Principal components analysis applied to the Delirium Rating Scale-Revised-98 contributes to understanding the delirium construct. Using a multisite pooled international delirium database, the authors applied confirmatory factor analysis to Delirium Rating Scale-Revised-98 scores from 859 adult patients evaluated by delirium experts (delirium, N=516; nondelirium, N=343). Confirmatory factor analysis found all diagnostic features and core symptoms (cognitive, language, thought process, sleep-wake cycle, motor retardation), except motor agitation, loaded onto factor 1. Motor agitation loaded onto factor 2 with noncore symptoms (delusions, affective lability, and perceptual disturbances). Factor 1 loading supports delirium as a single construct, but when accompanied by psychosis, motor agitation's role may not be solely as a circadian activity indicator.

Tank 241-AP-106, Grab samples, 6AP-98-1, 6AP-98-2 and 6AP-98-3 Analytical results for the final report

Energy Technology Data Exchange (ETDEWEB)

FULLER, R.K.

1999-02-23

This document is the final report for tank 241-AP-106 grab samples. Three grab samples 6AP-98-1, 6AP-98-2 and 6AP-98-3 were taken from riser 1 of tank 241-AP-106 on May 28, 1998 and received by the 222-S Laboratory on May 28, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) (Sasaki, 1998) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded. The request for sample analysis received for AP-106 indicated that the samples were polychlorinated biphenyl (PCB) suspects. The results of this analysis indicated that no PCBs were present at the Toxic Substance Control Act (TSCA) regulated limit of 50 ppm. The results and raw data for the PCB analysis are included in this document.

Tank 241-AP-106, Grab samples, 6AP-98-1, 6AP-98-2 and 6AP-98-3 Analytical results for the final report

International Nuclear Information System (INIS)

FULLER, R.K.

1999-01-01

This document is the final report for tank 241-AP-106 grab samples. Three grab samples 6AP-98-1, 6AP-98-2 and 6AP-98-3 were taken from riser 1 of tank 241-AP-106 on May 28, 1998 and received by the 222-S Laboratory on May 28, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) (Sasaki, 1998) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded. The request for sample analysis received for AP-106 indicated that the samples were polychlorinated biphenyl (PCB) suspects. The results of this analysis indicated that no PCBs were present at the Toxic Substance Control Act (TSCA) regulated limit of 50 ppm. The results and raw data for the PCB analysis are included in this document

45 CFR 98.3 - Effect on State law.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Effect on State law. 98.3 Section 98.3 Public... Goals, Purposes and Definitions § 98.3 Effect on State law. (a) Nothing in the Act or this part shall be construed to supersede or modify any provision of a State constitution or State law that prohibits the...

40 CFR 98.414 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Monitoring and QA/QC requirements. 98.414 Section 98.414 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.414 Monitoring...

40 CFR 98.415 - Procedures for estimating missing data.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data. 98.415 Section 98.415 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.415...

40 CFR 98.196 - Data reporting requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Data reporting requirements. 98.196 Section 98.196 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... use in a purification process). If CO2 was used on-site, provide the information in paragraphs (b)(17...

42 CFR 482.98 - Condition of participation: Human resources.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Condition of participation: Human resources. 482.98 Section 482.98 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Specialty Hospitals Transplant Center Process Requirements § 482.98 Condition of participation: Human...

Excitation functions of the 98Mo+d reactions

International Nuclear Information System (INIS)

Zarubin, P.P.; Padalko, V.Yu.; Khrisanfov, Yu.V.; Lebedev, P.P.; Podkopaev, Yu.N.

The excitation functions of the 98 Mo+d reactions were studied. The energy dependence of (d,p),(d,n) and (d,α) reactions was investigated by the activation analysis. The energies of deuterons in the range (6-12) MeV were determined by means of the aluminium filters. 98 Mo foils with surface densities of 1.02, 0.23 and 0.14 mgxcm -2 with 98 Mo enrichment of 94.1% were used as targets. The gamma spectra were measured by a Ge(Li) detector. The 98 Mo(d,p) 99 Mo reaction excitation function was determined via detection of 739 and 181 keV γ-radiation of 99 Mo (Tsub(1/2)=66.47h); 140 keV γ-radiation of 99 Tc (Tsub(1/2)=6h) was detected for the 98 Mo(d,n) 99 Tc reaction excitation function determination and 460, 568, 1091, 1200 and 1492 keV γ-quanta of 96 Nb (Tsub(1/2)=23.35h) - for the 98 Mo(d,α) 96 Nb reaction. In the excitation function the wide extremum was observed at Esub(d) approximately 10 MeV. The ratio of cross sections σsup(m)(d,n)/σ(d,p) on the 98 Mo target was determined. The ratio σsup(m)(d,n)/σ(d,p) was found to be decreasing function of the deuteron energy. The relative cross sections were determined with an accuracy of +-5%, while for the absolute values of cross sections the accuracy was +-15%

45 CFR 98.13 - Applying for Funds.

Science.gov (United States)

2010-10-01

... General Application Procedures § 98.13 Applying for Funds. The Lead Agency of a State or Territory shall... lobbying payments; (3) An assurance that the Lead Agency provides a drug-free workplace pursuant to 45 CFR... in § 98.17; and (d) Such other information as specified by the Secretary. ...

7 CFR 1786.98 - Discounted present value.

Science.gov (United States)

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Discounted present value. 1786.98 Section 1786.98... Discounted present value. (a) The Discounted Present Value shall be calculated by RUS before prepayment is made by summing the present values of all remaining payments on all outstanding notes according to the...

40 CFR 98.33 - Calculating GHG emissions.

Science.gov (United States)

2010-07-01

...)(2)(ii) of this section. MVC = Molar volume conversion factor (849.5 scf per kg-mole at standard... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Stationary Fuel Combustion Sources § 98.33 Calculating... volume of fuel combusted per year, from company records as defined in § 98.6 (express mass in short tons...

Dynamic association of NUP98 with the human genome.

Directory of Open Access Journals (Sweden)

Yun Liang

Full Text Available Faithful execution of developmental gene expression programs occurs at multiple levels and involves many different components such as transcription factors, histone-modification enzymes, and mRNA processing proteins. Recent evidence suggests that nucleoporins, well known components that control nucleo-cytoplasmic trafficking, have wide-ranging functions in developmental gene regulation that potentially extend beyond their role in nuclear transport. Whether the unexpected role of nuclear pore proteins in transcription regulation, which initially has been described in fungi and flies, also applies to human cells is unknown. Here we show at a genome-wide level that the nuclear pore protein NUP98 associates with developmentally regulated genes active during human embryonic stem cell differentiation. Overexpression of a dominant negative fragment of NUP98 levels decreases expression levels of NUP98-bound genes. In addition, we identify two modes of developmental gene regulation by NUP98 that are differentiated by the spatial localization of NUP98 target genes. Genes in the initial stage of developmental induction can associate with NUP98 that is embedded in the nuclear pores at the nuclear periphery. Alternatively, genes that are highly induced can interact with NUP98 in the nuclear interior, away from the nuclear pores. This work demonstrates for the first time that NUP98 dynamically associates with the human genome during differentiation, revealing a role of a nuclear pore protein in regulating developmental gene expression programs.

Human Endometrial CD98 Is Essential for Blastocyst Adhesion

Science.gov (United States)

Domínguez, Francisco; Simón, Carlos; Quiñonero, Alicia; Ramírez, Miguel Ángel; González-Muñoz, Elena; Burghardt, Hans; Cervero, Ana; Martínez, Sebastián; Pellicer, Antonio; Palacín, Manuel; Sánchez-Madrid, Francisco; Yáñez-Mó, María

2010-01-01

Background Understanding the molecular basis of embryonic implantation is of great clinical and biological relevance. Little is currently known about the adhesion receptors that determine endometrial receptivity for embryonic implantation in humans. Methods and Principal Findings Using two human endometrial cell lines characterized by low and high receptivity, we identified the membrane receptor CD98 as a novel molecule selectively and significantly associated with the receptive phenotype. In human endometrial samples, CD98 was the only molecule studied whose expression was restricted to the implantation window in human endometrial tissue. CD98 expression was restricted to the apical surface and included in tetraspanin-enriched microdomains of primary endometrial epithelial cells, as demonstrated by the biochemical association between CD98 and tetraspanin CD9. CD98 expression was induced in vitro by treatment of primary endometrial epithelial cells with human chorionic gonadotropin, 17-β-estradiol, LIF or EGF. Endometrial overexpression of CD98 or tetraspanin CD9 greatly enhanced mouse blastocyst adhesion, while their siRNA-mediated depletion reduced the blastocyst adhesion rate. Conclusions These results indicate that CD98, a component of tetraspanin-enriched microdomains, appears to be an important determinant of human endometrial receptivity during the implantation window. PMID:20976164

High-voltage horizontal shaft squirrel cage type induction motor TOSMIGHTY{sub TM}-T98 series; Yokojiku koatsu kagogata yudo dendoki TOSMIGHTY{sub TM}-T98 series

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

T98 series developed as succeeding series of T90 for as short as 2 years expanded a standardization range from 450- 630 to 450-900 in frame number, and covered a power range up to 15,000kW in 4-pole motor base. The concept of T98 series is as follows: (1) ON TIME (rapid correspondence to requests, delivery time shortest in the world), (2) ON SPEC (security for customer`s demand quality, satisfaction of various international standards), and (3) ON PRICE (compactness, space saving and reasonable price by development of elementary technologies through joint research with the research division). This series is placed as strategic series for sales promotion through the existing electronic catalog (CD-ROM) and acquisition of further BASEEFA certifications. (translated by NEDO)

High-voltage horizontal shaft squirrel cage type induction motor TOSMIGHTY[sub TM]-T98 series. Yokojiku koatsu kagogata yudo dendoki TOSMIGHTY[sub TM]-T98 series

Energy Technology Data Exchange (ETDEWEB)

1999-03-01

T98 series developed as succeeding series of T90 for as short as 2 years expanded a standardization range from 450- 630 to 450-900 in frame number, and covered a power range up to 15,000kW in 4-pole motor base. The concept of T98 series is as follows: (1) ON TIME (rapid correspondence to requests, delivery time shortest in the world), (2) ON SPEC (security for customer's demand quality, satisfaction of various international standards), and (3) ON PRICE (compactness, space saving and reasonable price by development of elementary technologies through joint research with the research division). This series is placed as strategic series for sales promotion through the existing electronic catalog (CD-ROM) and acquisition of further BASEEFA certifications. (translated by NEDO)

46 CFR 98.25-50 - Filling and discharge pipes.

Science.gov (United States)

2010-10-01

... with a secondary remote control of a type acceptable to the Commandant. (c) The excess flow, internal... 46 Shipping 4 2010-10-01 2010-10-01 false Filling and discharge pipes. 98.25-50 Section 98.25-50... § 98.25-50 Filling and discharge pipes. (a) Filling connections shall be provided with one of the...

40 CFR 98.70 - Definition of source category.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Definition of source category. 98.70... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.70 Definition of source category...-based feedstock produced via steam reforming of a hydrocarbon. (b) Ammonia manufacturing processes in...

7 CFR 98.1 - General.

Science.gov (United States)

2010-01-01

..., READY-TO-EAT (MRE's), MEATS, AND MEAT PRODUCTS MRE's, Meats, and Related Meat Food Products § 98.1 General. Analytical services of meat and meat food products are performed for fat, moisture, salt, protein...

40 CFR 98.417 - Records that must be retained.

Science.gov (United States)

2010-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.417 Records that... reported under § 98.416. (2) Records documenting the initial and periodic calibration of the gas...

98例癌症病人心理障碍分析及其干预措施%Analysis on psychological disorder and related factors in 98 patients with cancer and intervention measures thereon

Institute of Scientific and Technical Information of China (English)

Wenwu Wang; Xuenong Ouyang; Zhangshu Chen; Xi Chen

2009-01-01

Objective: The aim of this study was to analyze factors of psychological disorder experienced by 98 cancer patients and to probe into intervention measures in accordance with the corresponding bad psychological factors. Methods:A questionnaire survey was conducted in the test group (n = 98) by filling out a symptom checklist 90 (SCL-90). And then the survey result was compared with the normal group (n = 1388) contained in relevant references. Results: Except for hostile factor that was similar to normal level (P > 0.05), other 8 factors were higher than in normal group (P < 0.01). And the cancer patients were classified with the survey results. Conclusion: Compared with normal persons, cancer patients have more psychological problems and related intervention measures are sought necessarily to improve the quality of life, to advance the immune function and to prolong the survival time of patients.

9 CFR 98.36 - Animal semen from Canada.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Animal semen from Canada. 98.36... CERTAIN ANIMAL EMBRYOS AND ANIMAL SEMEN Certain Animal Semen § 98.36 Animal semen from Canada. (a) General importation requirements for animal semen from Canada. If the product is . . . Then . . . (1) Equine semen...

Impact of target volume coverage with Radiation Therapy Oncology Group (RTOG) 98-05 guidelines for transrectal ultrasound guided permanent Iodine-125 prostate implants

International Nuclear Information System (INIS)

Horwitz, Eric M.; Mitra, Raj K.; Uzzo, Robert G.; Das, Indra J.; Pinover, Wayne H.; Hanlon, Alexandra L.; McNeeley, Shawn W.; Hanks, Gerald E.

2003-01-01

Purpose: Despite the wide use of permanent prostate implants for the treatment of early stage prostate cancer, there is no consensus for optimal pre-implant planning guidelines that results in maximal post-implant target coverage. The purpose of this study was to compare post-implant target volume coverage and dosimetry between patients treated before and after Radiation Therapy Oncology Group (RTOG) 98-05 guidelines were adopted using several dosimetric endpoints. Materials and methods: Ten consecutively treated patients before the adoption of the RTOG 98-05 planning guidelines were compared with ten consecutively treated patients after implementation of the guidelines. Pre-implant planning for patients treated pre-RTOG was based on the clinical target volume (CTV) defined by the pre-implant TRUS definition of the prostate. The CTV was expanded in each dimension according to RTOG 98-05 and defined as the planning target volume. The evaluation target volume was defined as the post-implant computed tomography definition of the prostate based on RTOG 98-05 protocol recommendations. Implant quality indicators included V 100 , V 90 , V 100 , and Coverage Index (CI). Results: The pre-RTOG median V 100 , V 90 , D 90 , and CI values were 82.8, 88.9%, 126.5 Gy, and 17.1, respectively. The median post-RTOG V 100 , V 90 , D 90 , and CI values were 96.0, 97.8%, 169.2 Gy, and 4.0, respectively. These differences were all statistically significant. Conclusions: Implementation of the RTOG 98-05 implant planning guidelines has increased coverage of the prostate by the prescription isodose lines compared with our previous technique, as indicated by post-implant dosimetry indices such as V 100 , V 90 , D 90 . The CI was also improved significantly with the protocol guidelines. Our data confirms the validity of the RTOG 98-05 implant guidelines for pre-implant planning as it relates to enlargement of the CTV to ensure adequate margin between the CTV and the prescription isodose

40 CFR 81.98 - Burlington-Keokuk Interstate Air Quality Control Region.

Science.gov (United States)

2010-07-01

... Quality Control Region. 81.98 Section 81.98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.98 Burlington-Keokuk Interstate Air Quality Control Region. The Burlington-Keokuk Interstate Air Quality Control Region (Illinois-Iowa) is revised to consist of the...

40 CFR 98.57 - Records that must be retained.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Records that must be retained. 98.57 Section 98.57 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS...) Documentation of how process knowledge was used to estimate abatement technology destruction efficiency. (f...

40 CFR 98.214 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Monitoring and QA/QC requirements. 98.214 Section 98.214 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... standard method or other enhanced industry consensus standard method published by an industry consensus...

37 CFR 1.98 - Content of information disclosure statement.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Content of information disclosure statement. 1.98 Section 1.98 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing...

28 CFR 0.98 - Functions of Commissioner of Federal Prison Industries.

Science.gov (United States)

2010-07-01

... Prison Industries. 0.98 Section 0.98 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Bureau of Prisons § 0.98 Functions of Commissioner of Federal Prison Industries. The Director of the Bureau of Prisons is authorized as ex officio Commissioner of Federal Prison Industries and...

40 CFR 98.227 - Records that must be retained.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Records that must be retained. 98.227 Section 98.227 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... significant changes to process. (b) Documentation of how process knowledge was used to estimate abatement...

40 CFR 98.40 - Definition of the source category.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Definition of the source category. 98... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Electricity Generation § 98.40 Definition of the source... category does not include portable equipment, emergency equipment, or emergency generators, as defined in...

9 CFR 98.17 - Procedures.

Science.gov (United States)

2010-01-01

... artificial insemination, natural breeding, and cleaning and disinfection, must be performed under the... unit and before entering any room or area listed in § 98.16 of this subpart. (d) Cleaning, disinfection... water and disinfected before being used to store the embryos. (7) The room used for cleaning and...

40 CFR 98.244 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... NIST Handbook 44 (2009) (incorporated by reference, see § 98.7) or follow procedures specified by the... Natural Gas by Gas Chromatography (incorporated by reference, see § 98.7). (ii) ASTM D6060-96 (Reapproved..., Other Hydrocarbons, and Carbon Dioxide in High-Purity Ethylene by Gas Chromatography (incorporated by...

46 CFR 98.25-5 - How anhydrous ammonia may be carried.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false How anhydrous ammonia may be carried. 98.25-5 Section 98... Anhydrous Ammonia in Bulk § 98.25-5 How anhydrous ammonia may be carried. (a) Anhydrous ammonia shall be..., except as otherwise provided in paragraph (b) of this section. (b) When anhydrous ammonia is to be...

40 CFR 98.420 - Definition of the source category.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Definition of the source category. 98.420 Section 98.420 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... distribution of CO2. (4) Purification, compression, or processing of CO2. (5) On-site use of CO2 captured on...

40 CFR 98.174 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Iron and Steel Production § 98.174 Monitoring and QA/QC... moisture content of the stack gas. (5) Determine the mass rate of process feed or process production (as... Fusion Techniques (incorporated by reference, see § 98.7) for iron and ferrous scrap. (v) ASM CS-104 UNS...

Extensions to EMS-98 to match the conditions of Romania

International Nuclear Information System (INIS)

Sandi, H.; Borcia, I. S.

2002-01-01

EMS-98 (European Macroseismic Scale '98) was endorsed in 1998 by the European Seismological Commission and recommended for extensive use in the European area. A comparison of EMS-98 with previous macroseismic scales as e.g. MSK (also endorsed by ESC in the past) puts into evidence important elements of superiority of EMS and makes it possible to conclude that EMS-98 represents currently a peak development in the succession of macroseismic scales of traditional kind. Given this fact, it is reasonable if not mandatory to replace the current Romanian standard STAS 3684-71, which relies on the MSK-64 scale, by an official document endorsing the application in Romania of EMS-98. The developments presented rely on a project developed jointly by INCERC and the Institute of Geodynamics under support from the Ministry of Public Works, Transportation and Housing. The project was aimed at presenting a translation of the version of EMS-98 already published, with some additional developments aimed at providing a better applicability to the conditions of Romania (keeping in view, primarily, two facts: the features of ground motion due to Vrancea earthquakes and the features of the building stock that would generate, through its performance, the bulk of macroseismic information in the event of strong earthquakes). The features of ground motion due to Vrancea earthquakes are characterized, first of all, by a wide variety of spectral characteristics, varying during one event from one site to the other and, for many sites, also from one event to the other. This has obvious implications for the task of estimating intensity and should be reflected in some suitable way in the criteria for intensity assessment. Unfortunately, to date there is no concern in the frame of EMS-98 for the spectral characteristics of ground motion. Introducing criteria that could reflect the spectral characteristics would require a full rethinking and reshaping of EMS-98, so this aspect could not be tackled

2020 Vision Project Summary, FY98

Energy Technology Data Exchange (ETDEWEB)

A Munoz; J. C. Clausen; K. P. Scott; K. W. Gordon

1998-11-01

The 2020 Vision project began in 1996 with two participating teachers and four classes. It has since grown to comprise more than a dozen participating teachers and hundreds of students across the country. Much of this growth took place in FY98, thanks to the accomplishment of several major goals: implementation of a mentor program, enhanced teacher training, a mid-year conference for students, recruitment of distant schools, and the development of an interactive Web site. The first part of this report describes these accomplishments, as well as future directions for 2020 Vision. The second part summarized the scenarios students wrote during the 1997-98 school year. it identifies recurrent themes in the students' scenarios and compares/contrasts them with scenarios written in the first two years of the project.

7 CFR 98.2 - Definitions.

Science.gov (United States)

2010-01-01

..., READY-TO-EAT (MRE's), MEATS, AND MEAT PRODUCTS MRE's, Meats, and Related Meat Food Products § 98.2... from clean and sound edible tissues from swine. Meals, Ready-To-Eat (MRE). Meals, Ready-To-Eat are... advertised solely to the medical profession is not included. Ready-to-eat. The term means consumers are...

Relationship between S. typhi R plasmid (pRST98) and macrophage apoptosis

International Nuclear Information System (INIS)

Song Guorong; Wu Shuyan; Li Yuanyuan; Lv Jie; Xu Yang; Huang Rui

2008-01-01

Objective: To study the relationship between S. typhi R plasmid (pR ST98 ) and macrophage apoptosis. Methods: pR ST98 was transferred into a less virulent strain of S. typhimurium for creating a transconjugant pR ST98 /RIA, the standard S. typhimurium virulence strain SR-11 was used as the positive control, and RIA as the negative one. Infection with murine macrophage J 774A.1 occurred separately under the same conditions. J 774A.1 apoptosis was detected by flow cytometry and TUNEL at 0, 2, 4, 6, 12, 24 hours respectively. Mitochondria membrane potential was detected by JC-1 staining method. Viable bacteria was detected by serial dilution at the same time and viable cells stained with Trypan blue were counted. Results: SR-11 results in a higher apoptosis in J 774A.1 than pR ST98 /RIA, and a combined pR ST98 /RIA higher than RIA (P pR ST98 /RIA>SR-11 (P ST98 could increase the macrophage apoptosis. (authors)

45 CFR 98.47 - Nondiscrimination in employment on the basis of religion.

Science.gov (United States)

2010-10-01

... religion. 98.47 Section 98.47 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... Requirements § 98.47 Nondiscrimination in employment on the basis of religion. (a) In general, except as... religion. (1) Child care providers that receive assistance through grants or contracts under the CCDF shall...

The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort.

Science.gov (United States)

García-García, Gema; Besnard, Thomas; Baux, David; Vaché, Christel; Aller, Elena; Malcolm, Sue; Claustres, Mireille; Millan, Jose M; Roux, Anne-Françoise

2013-01-01

Usher syndrome type 2 (USH2) is an autosomal recessive disease characterized by moderate to severe hearing loss and retinitis pigmentosa. To date, three disease-causing genes have been identified, USH2A, GPR98, and DFNB31, of which USH2A is clearly the major contributor. The aim of this work was to determine the contribution of GPR98 and DFNB31 genes in a Spanish cohort of USH2A negative patients using exhaustive molecular analysis, including sequencing, dosage, and splicing analysis. Linkage analysis was performed to prioritize the gene to study, followed by sequencing of exons and intron-exon boundaries of the selected gene, GPR98 (90 exons) or DFNB31 (12 exons). Functional splicing analyses and comparative genomic hybridization array to detect large rearrangements were performed when appropriate. We confirmed that mutations in GPR98 contribute a significant but minor role to Usher syndrome type 2. In a group of patients referred for molecular diagnosis, 43 had been found to be positive for USH2A mutations, the remaining 19 without USH2A alterations were screened, and seven different mutations were identified in the GPR98 gene in seven patients (five in the homozygous state), of which six were novel. All detected mutations result in a truncated protein; deleterious missense mutations were not found. No pathological mutations were identified in the DFNB31 gene. In Spain, USH2A and GPR98 are responsible for 95.8% and 5.2% of USH2 mutated cases, respectively. DFNB31 plays a minor role in the Spanish population. There was a group of patients in whom no mutation was found. These findings confirm the importance of including at least GPR98 analysis for comprehensive USH2 molecular diagnosis.

40 CFR 98.7 - What standardized methods are incorporated by reference into this part?

Science.gov (United States)

2010-07-01

... Hydraulic Cement, IBR approved for §§ 98.84(a), 98.84(b), and 98.84(c). (3) ASTM D235-02 (Reapproved 2007... Method for Density, Relative Density (Specific Gravity), or API Gravity of Crude Petroleum and Liquid..., Compressibility Factor, and Relative Density of Gaseous Fuels, IBR approved for §§ 98.34(a) and 98.254(e). (21...

45 CFR 98.46 - Nondiscrimination in admissions on the basis of religion.

Science.gov (United States)

2010-10-01

... religion. 98.46 Section 98.46 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... Requirements § 98.46 Nondiscrimination in admissions on the basis of religion. (a) Child care providers (other... contracts under the CCDF shall not discriminate in admissions against any child on the basis of religion. (b...

Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.

Science.gov (United States)

Fahrenkrog, Birthe; Martinelli, Valérie; Nilles, Nadine; Fruhmann, Gernot; Chatel, Guillaume; Juge, Sabine; Sauder, Ursula; Di Giacomo, Danika; Mecucci, Cristina; Schwaller, Jürg

2016-01-01

Chromosomal translocations involving the nucleoporin NUP98 have been described in several hematopoietic malignancies, in particular acute myeloid leukemia (AML). In the resulting chimeric proteins, Nup98's N-terminal region is fused to the C-terminal region of about 30 different partners, including homeodomain (HD) transcription factors. While transcriptional targets of distinct Nup98 chimeras related to immortalization are relatively well described, little is known about other potential cellular effects of these fusion proteins. By comparing the sub-nuclear localization of a large number of Nup98 fusions with HD and non-HD partners throughout the cell cycle we found that while all Nup98 chimeras were nuclear during interphase, only Nup98-HD fusion proteins exhibited a characteristic speckled appearance. During mitosis, only Nup98-HD fusions were concentrated on chromosomes. Despite the difference in localization, all tested Nup98 chimera provoked morphological alterations in the nuclear envelope (NE), in particular affecting the nuclear lamina and the lamina-associated polypeptide 2α (LAP2α). Importantly, such aberrations were not only observed in transiently transfected HeLa cells but also in mouse bone marrow cells immortalized by Nup98 fusions and in cells derived from leukemia patients harboring Nup98 fusions. Our findings unravel Nup98 fusion-associated NE alterations that may contribute to leukemogenesis.

Korean Version of the Delirium Rating Scale-Revised-98: Reliability and Validity

Science.gov (United States)

Ryu, Jian; Lee, Jinyoung; Kim, Hwi-Jung; Shin, Im Hee; Kim, Jeong-Lan; Trzepacz, Paula T.

2011-01-01

Objective The aims of the present study were 1) to standardize the validity and reliability of the Korean version of Delirium Rating Scale-Revised-98 (DRS-R98-K) and 2) to establish the optimum cut-off value, sensitivity, and specificity for discriminating delirium from other non-delirious psychiatric conditions. Methods Using DSM-IV criteria, 157 subjects (69 delirium, 29 dementia, 32 schizophrenia, and 27 other psychiatric patients) were enrolled. Subjects were evaluated using DRS-R98-K, DRS-K, Mini-Mental State Examination (MMSE-K), and Clinical Global Impression-Severity (CGI-S) scale. Results DRS-R98-K total and severity scores showed high correlations with DRS-K. They were significantly different across all groups (p=0.000). However, neither MMSE-K nor CGI-S distinguished delirium from dementia. All DRS-R98-K diagnostic items (#14-16) and items #1 and 2 significantly discriminated delirium from dementia. Cronbach's alpha coefficient revealed high internal consistency for DRS-R98-K total (r=0.91) and severity (r=0.89) scales. Interrater reliability (ICC between 0.96 and 1) was very high. Using receiver operating characteristic analysis, the area under the curve of DRS-R98-K total score was 0.948 between the delirium group and all other groups and 0.873 between the delirium and dementia groups. The best cut-off scores in DRS-R98-K total score were 18.5 and 19.5 between the delirium and the other three groups and 20.5 between the delirium and dementia groups. Conclusion We demonstrated that DRS-R98-K is a valid and reliable instrument for assessing delirium severity and diagnosis and discriminating delirium from dementia and other psychiatric disorders in Korean patients. PMID:21519534

49 CFR 98.12 - Administrative sanctions.

Science.gov (United States)

2010-10-01

... an administrative sanction against a former employee who, after a final administrative decision under... imposed under subsection (a) of this section are: (1) Prohibiting the former employee from making, on... ACTIVITIES Administrative Sanctions § 98.12 Administrative sanctions. (a) The Secretary, in decisions under...

Glycoprotein CD98 as a receptor for colitis-targeted delivery of nanoparticle.

Science.gov (United States)

Xiao, Bo; Yang, Yang; Viennois, Emilie; Zhang, Yuchen; Ayyadurai, Saravanan; Baker, Mark; Laroui, Hamed; Merlin, Didier

2014-03-21

Treatment strategies for inflammatory bowel disease have been constrained by limited therapeutic efficacy and serious adverse effects owing to a lack of receptor for targeted drug delivery to the inflamed colon. Upon inflammation, CD98 expression is highly elevated in colonic epithelial cells and infiltrating immune cells. To investigate whether CD98 can be used as a colitis-targeted delivery receptor, we constructed CD98 Fab'-bearing quantum dots (QDs)-loaded nanoparticles (Fab'-NPs). The resultant Fab'-NPs had desired particle size (~458 nm) with a narrow size distribution and zeta-potential (approximately +19 mV), low cytotoxicity, and excellent fluorescence properties. Electron microscopy images provided direct evidence for the well-dispersed distribution of QDs within spherical Fab'-NPs. Cellular uptake experiments demonstrated that Fab'-NPs were efficiently internalized into Colon-26 and RAW 264.7 cells through the CD98-mediated endocytosis pathway, and showed that the targeting effect of CD98 Fab' markedly increased their cellular uptake efficiency compared with control pegylated QDs-loaded NPs (PEG-NPs). Furthermore, ex vivo studies showed much more effective accumulation of Fab'-NPs in colitis tissue than that of PEG-NPs. These findings suggest that because of inflammation-dependent over-expression of CD98, active colitis-targeted delivery can be accomplished using NPs decorated with CD98 antibody.

ISO-PC Version 1.98: User`s guide

Energy Technology Data Exchange (ETDEWEB)

Rittmann, P.D.

1995-05-02

This document describes how to use Version 1.98 of the shielding program named ISO-PC. Version 1.98 corrects all known errors in ISOSHLD-II. In addition, a few numeric problems have been eliminated. There are three new namelist variables, 25 additional shielding materials, and 5 more energy groups. The two major differences with the original ISOSHLD-II are the removal of RIBD(radioisotope buildup and decay) source generator, and the removal of the non-uniform source distribution parameter, SSV1. This version of ISO-PC works with photon energies from 10 KeV to 10 MeV using 30 energy groups.

Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression

Directory of Open Access Journals (Sweden)

Bo Wu

2016-11-01

Full Text Available Hepatocellular carcinoma (HCC is currently the third most common cause of cancer-related death in the Asia-Pacific region. Our previous work showed that knockdown of CD98 significantly inhibits malignant HCC cell phenotypes in vitro and in vivo. The level of CD98 in the membrane is tightly regulated to mediate complex processes associated with cell–cell communication and intracellular signaling. In addition, the intracellular domain of CD98 (CD98-ICD seems to be of vital importance for recycling CD98 to the membrane after it is endocytosed. The intracellular and transmembrane domains of CD98 associate with β-integrins (primarily β1 but also β3, and this association is essential for CD98 mediation of integrin-like signaling and complements dominant suppression of β1-integrin. We speculated that isolated CD98-ICD would similarly suppress β1-integrin activation and inhibit the malignant behaviors of cancer cells. In particular, the exact role of CD98-ICD has not been studied independently in HCC. In this study, we found that ectopic expression of CD98-ICD inhibited the malignant phenotypes of HCC cells, and the mechanism possibly involves β1-integrin suppression. Moreover, the expression levels of CD98, β1-integrin-A (the activated form of β1-integrin and Ki-67 were significantly increased in HCC tissues relative to those of normal liver tissues. Therefore, our preliminary study indicates that ectopic CD98-ICD has an inhibitory role in the malignant development of HCC, and shows that CD98-ICD acts as a dominant negative mutant of CD98 that attenuates β1-integrin activation. CD98-ICD may emerge as a promising candidate for antitumor treatment.

Direct photons in WA98

CERN Document Server

Aggarwal, M M; Ahammed, Z; Angelis, Aris L S; Antonenko, V G; Arefev, V; Astakhov, V A; Avdeichikov, V; Awes, T C; Baba, P V K S; Badyal, S K; Barlag, C; Bathe, S; Batyunya, B; Bernier, T; Bhalla, K B; Bhatia, V S; Blume, C; Bock, R; Bohne, E M; Böröcz, Z K; Bucher, D; Buijs, A; Büsching, H; Carlén, L; Chalyshev, V; Chattopadhyay, S; Cherbachev, R; Chujo, T; Claussen, A; Das, A C; Decowski, M P; Delagrange, H; Dzhordzhadze, V; Dönni, P; Dubovik, I; Dutt, S; Dutta-Majumdar, M R; El-Chenawi, K F; Eliseev, S; Enosawa, K; Foka, P Y; Fokin, S L; Ganti, M S; Garpman, S; Gavrishchuk, O P; Geurts, F J M; Ghosh, T K; Glasow, R; Gupta, S K; Guskov, B; Gustafsson, Hans Åke; Gutbrod, H H; Higuchi, R; Hrivnacova, I; Ippolitov, M S; Kalechofsky, H; Kamermans, R; Kampert, K H; Karadzhev, K; Karpio, K; Kato, S; Kees, S; Klein-Bösing, C; Knoche, S; Kolb, B W; Kosarev, I G; Kucheryaev, I; Krümpel, T; Kugler, A; Kulinich, P A; Kurata, M; Kurita, K; Kuzmin, N A; Langbein, I; Lee, Y Y; Löhner, H; Luquin, Lionel; Mahapatra, D P; Man'ko, V I; Martin, M; Martínez, G; Maksimov, A; Mgebrishvili, G; Miake, Y; Mir, M F; Mishra, G C; Miyamoto, Y; Mohanty, B; Morrison, D; Mukhopadhyay, D S; Naef, H; Nandi, B K; Nayak, S K; Nayak, T K; Neumaier, S; Nyanin, A; Nikitin, V A; Nikolaev, S; Nilsson, P O; Nishimura, S; Nomokonov, V P; Nystrand, J; Obenshain, F E; Oskarsson, A; Otterlund, I; Pachr, M; Pavlyuk, S; Peitzmann, Thomas; Petracek, V; Pinganaud, W; Plasil, F; Von Poblotzki, U; Purschke, M L; Rak, J; Raniwala, R; Raniwala, S; Ramamurthy, V S; Rao, N K; Retière, F; Reygers, K; Roland, G; Rosselet, L; Rufanov, I A; Roy, C; Rubio, J M; Sako, H; Sambyal, S S; Santo, R; Sato, S; Schlagheck, H; Schmidt, H R; Schutz, Y; Shabratova, G; Shah, T H; Sibiryak, Yu; Siemiarczuk, T; Silvermyr, D; Sinha, B C; Slavin, N V; Söderström, K; Solomey, Nickolas; Sood, G; Sørensen, S P; Stankus, P; Stefanek, G; Steinberg, P; Stenlund, E; Stüken, D; Sumbera, M; Svensson, S; Trivedi, M D; Tsvetkov, A A; Tykarski, L; Urbahn, J; Van den Pijll, E C; van Eijndhoven, N; van Nieuwenhuizen, G J; Vinogradov, A; Viyogi, Y P; Vodopyanov, A S; Vörös, S; Wyslouch, B; Yagi, K; Yokota, Y; Young, G R

2002-01-01

A measurement of direct photon production in /sup 208/Pb+/sup 208/Pb collisions at 158 A GeV has been carried out in the CERN WA98 experiment. The invariant yield of direct photons was extracted as a function of transverse momentum in the interval 0.51.5 GeV/c. the result constitutes the first observation of direct photons in ultrarelativistic heavy-ion collisions. (19 refs).

45 CFR 98.16 - Plan provisions.

Science.gov (United States)

2010-10-01

... in the TANF work requirement applicable to a single custodial parent caring for a child under age six... for purposes of child care eligibility; and whether respite care is provided to custodial parents of... meet the needs of certain families specified at § 98.50(e). (5) Any additional eligibility criteria...

A large deletion in GPR98 causes type IIC Usher syndrome in male and female members of an Iranian family.

Science.gov (United States)

Hilgert, N; Kahrizi, K; Dieltjens, N; Bazazzadegan, N; Najmabadi, H; Smith, R J H; Van Camp, G

2009-04-01

Usher syndrome (USH) is a clinically and genetically heterogeneous disease. The three recognised clinical phenotypes (types I, II and III; USH1, USH2 and USH3) are caused by mutations in nine different genes. USH2C is characterised by moderate to severe hearing loss, retinitis pigmentosa and normal vestibular function. One earlier report describes mutations in GPR98 (VLGR1) in four families segregating this phenotype. To detect the disease-causing mutation in an Iranian family segregating USH2C. In this family, five members had a phenotype compatible with Usher syndrome, and two others had nonsyndromic hearing loss. Mutation analysis of all 90 coding exons of GPR98. Consistent with these clinical findings, the five subjects with USH carried a haplotype linked to the USH2C locus, whereas the two subjects with nonsyndromic hearing loss did not. We identified a new mutation in GPR98 segregating with USH2C in this family. The mutation is a large deletion g.371657_507673del of exons 84 and 85, presumably leading to a frameshift. A large GPR98 deletion of 136 017 bp segregates with USH2C in an Iranian family. To our knowledge, this is only the second report of a GPR98 mutation, and the first report on male subjects with USH2C and a GPR98 mutation.

MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells.

Science.gov (United States)

Zhu, Weimin; Huang, Yijiao; Pan, Qi; Xiang, Pei; Xie, Nanlan; Yu, Hao

2017-03-01

Warburg effect is a hallmark of cancer cells. Accumulating evidence suggests that microRNAs (miRs) could regulate such metabolic reprograming. Aberrant expression of miR-98 has been observed in many types of cancers. However, its functions and significance in colon cancer remain largely elusive. To investigate miR-98 expression and the biological functions in colon cancer progression. miR-98 expression levels were determined by quantitative RT-PCR in 215 cases of colon cancer samples. miR-98 mimic or inhibitor was used to test the biological functions in SW480 and HCT116 cells, followed by cell proliferation assay, lactate production, glucose uptake, and cellular ATP levels assay and extracellular acidification rates measurement. Western blot and luciferase assay were used to identify the target of miR-98. miR-98 was significantly down-regulated in colon cancer tissues compared to adjacent colon tissues and acted as a suppressor for Warburg effect in cancer cells. miR-98 inhibited glycolysis by directly targeting hexokinase 2, or HK2, illustrating a novel pathway to mediate Warburg effect of cancer cells. In vitro experiments further indicated that HK2 was involved in miR-98-mediated suppression of glucose uptake, lactate production, and cell proliferation. In addition, we detected HK2 expression in colon cancer tissues and found that the expressions of miR-98 and HK2 were negatively correlated. miR-98 acts as tumor suppressor gene and inhibits Warburg effect in colon cancer cells, which provided potential targets for clinical treatments.

9 CFR 98.33 - Ports designated for the importation of certain animal semen.

Science.gov (United States)

2010-01-01

... of certain animal semen. 98.33 Section 98.33 Animals and Animal Products ANIMAL AND PLANT HEALTH... ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMAL EMBRYOS AND ANIMAL SEMEN Certain Animal Semen § 98.33 Ports designated for the importation of certain animal semen. (a) Air and ocean ports. The following air and ocean...

45 CFR 98.20 - A child's eligibility for child care services.

Science.gov (United States)

2010-10-01

..., ethnic background, sex, religious affiliation, or disability; (2) Limit parental rights provided under... 45 Public Welfare 1 2010-10-01 2010-10-01 false A child's eligibility for child care services. 98.20 Section 98.20 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD...

Glycoprotein CD98 as a receptor for colitis-targeted delivery of nanoparticle†

OpenAIRE

Xiao, Bo; Yang, Yang; Viennois, Emilie; Zhang, Yuchen; Ayyadurai, Saravanan; Baker, Mark; Laroui, Hamed; Merlin, Didier

2014-01-01

Treatment strategies for inflammatory bowel disease have been constrained by limited therapeutic efficacy and serious adverse effects owing to a lack of receptor for targeted drug delivery to the inflamed colon. Upon inflammation, CD98 expression is highly elevated in colonic epithelial cells and infiltrating immune cells. To investigate whether CD98 can be used as a colitis-targeted delivery receptor, we constructed CD98 Fab′-bearing quantum dots (QDs)-loaded nanoparticles (Fab′-NPs). The re...

29 CFR 98.600 - How do suspension and debarment actions start?

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true How do suspension and debarment actions start? 98.600 Section 98.600 Labor Office of the Secretary of Labor GOVERNMENTWIDE DEBARMENT AND SUSPENSION... debarment actions start? When we receive information from any source concerning a cause for suspension or...

List of isozyme loci - RGP gmap98 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us RGP gmap98 List of isozyme loci Data detail Data name List of isozyme loci DOI 10.18908/lsdb...he present high-density linkage map, and that were putatively identified as isozyme genes. Data file File name: rgp_gmap98_iso...gmap98/LATEST/rgp_gmap98_isozyme_loci.zip File size: 611 B Simple search URL http://togodb.biosciencedbc.jp/...0001 were considered as functionally identical clones. And we have selected the ones that hit the isozyme ge...his Database Database Description Download License Update History of This Database Site Policy | Contact Us List of isozyme loci - RGP gmap98 | LSDB Archive ...

Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9.

Directory of Open Access Journals (Sweden)

Enas R Yassin

2009-08-01

Full Text Available NUP98-HOXA9 is the prototype of a group of oncoproteins associated with acute myeloid leukemia. It consists of an N-terminal portion of NUP98 fused to the homeodomain of HOXA9 and is believed to act as an aberrant transcription factor that binds DNA through the homeodomain. Here we show that NUP98-HOXA9 can regulate transcription without binding to DNA. In order to determine the relative contributions of the NUP98 and HOXA9 portions to the transforming ability of NUP98-HOXA9, the effects of NUP98-HOXA9 on primary human CD34+ cells were dissected and compared to those of wild-type HOXA9. In contrast to previous findings in mouse cells, HOXA9 had only mild effects on the differentiation and proliferation of primary human hematopoietic cells. The ability of NUP98-HOXA9 to disrupt the differentiation of primary human CD34+ cells was found to depend primarily on the NUP98 portion, whereas induction of long-term proliferation required both the NUP98 moiety and an intact homeodomain. Using oligonucleotide microarrays in primary human CD34+ cells, a group of genes was identified whose dysregulation by NUP98-HOXA9 is attributable primarily to the NUP98 portion. These include RAP1A, HEY1, and PTGS2 (COX-2. Their functions may reflect the contribution of the NUP98 moiety of NUP98-HOXA9 to leukemic transformation. Taken together, these results suggest that the effects of NUP98-HOXA9 on gene transcription and cell transformation are mediated by at least two distinct mechanisms: one that involves promoter binding through the homeodomain with direct transcriptional activation, and another that depends predominantly on the NUP98 moiety and does not involve direct DNA binding.

Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins.

Science.gov (United States)

Takeda, Akiko; Sarma, Nayan J; Abdul-Nabi, Anmaar M; Yaseen, Nabeel R

2010-05-21

NUP98 is a nucleoporin that plays complex roles in the nucleocytoplasmic trafficking of macromolecules. Rearrangements of the NUP98 gene in human leukemia result in the expression of numerous fusion oncoproteins whose effect on nucleocytoplasmic trafficking is poorly understood. The present study was undertaken to determine the effects of leukemogenic NUP98 fusion proteins on CRM1-mediated nuclear export. NUP98-HOXA9, a prototypic NUP98 fusion, inhibited the nuclear export of two known CRM1 substrates: mutated cytoplasmic nucleophosmin and HIV-1 Rev. In vitro binding assays revealed that NUP98-HOXA9 binds CRM1 through the FG repeat motif in a Ran-GTP-dependent manner similar to but stronger than the interaction between CRM1 and its export substrates. Two NUP98 fusions, NUP98-HOXA9 and NUP98-DDX10, whose fusion partners are structurally and functionally unrelated, interacted with endogenous CRM1 in myeloid cells as shown by co-immunoprecipitation. These leukemogenic NUP98 fusion proteins interacted with CRM1, Ran, and the nucleoporin NUP214 in a manner fundamentally different from that of wild-type NUP98. NUP98-HOXA9 and NUP98-DDX10 formed characteristic aggregates within the nuclei of a myeloid cell line and primary human CD34+ cells and caused aberrant localization of CRM1 to these aggregates. These NUP98 fusions caused nuclear accumulation of two transcription factors, NFAT and NFkappaB, that are regulated by CRM1-mediated export. The nuclear entrapment of NFAT and NFkappaB correlated with enhanced transcription from promoters responsive to these transcription factors. Taken together, the results suggest a new mechanism by which NUP98 fusions dysregulate transcription and cause leukemia, namely, inhibition of CRM1-mediated nuclear export with aberrant nuclear retention of transcriptional regulators.

What will the /sup 98/Mo solar-neutrino experiment measure?

International Nuclear Information System (INIS)

Bahcall, J.N.

1988-01-01

It is shown that the geochemical measurement of the solar-neutrino flux using /sup 98/Mo should yield the same value for the 8 B neutrino flux as is determined by contemporary observations using the /sup 37/Cl and Kamiokande II detectors. The /sup 98/Mo and contemporary fluxes should be equal to an accuracy of better than 1%, provided standard ideas regarding time scales in stellar evolution are correct

40 CFR 98.362 - GHGs to report.

Science.gov (United States)

2010-07-01

... because of emissions from manure management system components is not required to report emissions from... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Manure Management § 98.362 GHGs to report. (a) Livestock facilities must report...

STS-98 Crew Interview: Tom Jones

Science.gov (United States)

2001-01-01

The STS-98 Mission Specialist Tom Jones is seen being interviewed. He answers questions about his inspiration to become an astronaut, his career path, and his training. He gives details on the mission's goals and significance, and the payload and hardware it brings to the International Space Station (ISS). Mr. Jones discusses his role in the mission's spacewalks and activities.

40 CFR 98.73 - Calculating GHG emissions.

Science.gov (United States)

2010-07-01

...). MW = Molecular weight of the gaseous feedstock (kg/kg-mole). MVC = Molar volume conversion factor... stream (kg/kg-mole). MVC = Molar volume conversion factor (849.5 scf per kg-mole at standard conditions... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.73 Calculating GHG emissions. You...

40 CFR 98.243 - Calculating GHG emissions.

Science.gov (United States)

2010-07-01

... feedstock). (MWf)i = Molecular weight of gaseous feedstock i (kg/kg-mole). MVC = Molar volume conversion... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.243 Calculating GHG emissions. (a) If you route all process vent emissions and emissions from combustion of process off-gas to one...

40 CFR 98.76 - Data reporting requirements.

Science.gov (United States)

2010-07-01

... facility uses gaseous feedstock, the molar volume conversion factor of the gaseous feedstock (scf per kg... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In...). (14) Volume of the waste recycle stream for month n for each ammonia process unit (scf) (15) Method...

RRDF-98. Russian reactor dosimetry file. Summary documentation

International Nuclear Information System (INIS)

Pashchenko, A.B.

1999-01-01

This document summarizes the contents and documentation of the new version of tile Russian Reactor Dosimetry File (RRDF-98) released in December 1998 by the Russian Center on Nuclear Data (CJD) at the Institute of Physics and Power Engineering, Russian Federation. This file contains the original evaluations of cross section data and covariance matrixes for 22 reactions which are used for neutron flux dosimetry by foil activation. The majority of the evaluations included in previous versions of the Russian Reactor Dosimetry Files (BOSPOR-80, RRGF-94 and RRDF-96) have been superseded by new evaluations. The evaluated cross sections of RRDF-98 averaged over 252-Cf and 235-U fission spectra are compared with relevant integral data. The data file is available from the IAEA Nuclear Data Section on diskette, cost free. (author)

7 CFR 98.5 - Fees and charges.

Science.gov (United States)

2010-01-01

... MEALS, READY-TO-EAT (MRE's), MEATS, AND MEAT PRODUCTS MRE's, Meats, and Related Meat Food Products § 98.5 Fees and charges. (a) The fee charged for any single laboratory analysis of meat, meat food..., meat food products, and MRE's, not covered by a cooperative agreement, shall result in an additional...

Contrasting terrestrial carbon cycle responses to the 1997/98 and 2015/16 extreme El Niño events

Science.gov (United States)

Wang, Jun; Zeng, Ning; Wang, Meirong; Jiang, Fei; Wang, Hengmao; Jiang, Ziqiang

2018-01-01

conditions enhanced GPP and TER over Eurasia during the 2015/16 El Niño, while these fluxes were suppressed during 1997/98. The total extratropical Northern Hemisphere GPP and TER anomalies were 0.63 and 0.55 Pg C yr-1 during1997/98, and 1.90 and 1.45 Pg C yr-1 during 2015/16, respectively. Additionally, wildfires played a less important role during the 2015/16 than during the 1997/98 El Niño.

40 CFR 98.173 - Calculating GHG emissions.

Science.gov (United States)

2010-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Iron and Steel Production § 98.173 Calculating GHG emissions... for the process as specified in paragraphs (b)(1)(i) through (b)(1)(vii) of this section. The... the gaseous fuel (kg/kg-mole). MVC = Molar volume conversion factor (849.5 scf per kg-mole at standard...

38 CFR 17.98 - Mental health services.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Mental health services... Outpatient Treatment § 17.98 Mental health services. (a) Following the death of a veteran, bereavement... mental health services in connection with treatment of the veteran under 38 U.S.C. 1710, 1712, 1712A...

40 CFR 98.163 - Calculating GHG emissions.

Science.gov (United States)

2010-07-01

... = Molecular weight of the gaseous fuel and feedstock (kg/kg-mole). MVC = Molar volume conversion factor (849.5... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Hydrogen Production § 98.163 Calculating GHG emissions. You... = Volume of the gaseous fuel and feedstock used in month n (scf (at standard conditions of 68 °F and...

Massage Therapy for 98 Cases of Ankle Sprain Patients%按摩治疗踝关节扭伤98例

Institute of Scientific and Technical Information of China (English)

周合成

2013-01-01

Objective:To observe the efficacy of treating ankle sprain by massage therapy. Methods:98 cases of ankle sprain patients were all treated by massage therapy. Results:88 cases were cured, 6 cases had marked effect, 2 cases were effecitve, 2 cases had no effect, the total effective rate was 97.95%. Conclusion:Massage therapy has a significant curative effect on ankle sprain.%目的：观察按摩治疗踝关节扭伤的疗效。方法：对98例踝关节扭伤患者进行按摩治疗。结果：痊愈88例，显效6例，有效2例，无效2例，总有效率为97.95%。结论：按摩治疗踝关节扭伤疗效显著。

RRDF-98. Russian reactor dosimetry file. Summary documentation

Energy Technology Data Exchange (ETDEWEB)

Pashchenko, A B

1999-03-01

This document summarizes the contents and documentation of the new version of tile Russian Reactor Dosimetry File (RRDF-98) released in December 1998 by the Russian Center on Nuclear Data (CJD) at the Institute of Physics and Power Engineering, Russian Federation. This file contains the original evaluations of cross section data and covariance matrixes for 22 reactions which are used for neutron flux dosimetry by foil activation. The majority of the evaluations included in previous versions of the Russian Reactor Dosimetry Files (BOSPOR-80, RRGF-94 and RRDF-96) have been superseded by new evaluations. The evaluated cross sections of RRDF-98 averaged over 252-Cf and 235-U fission spectra are compared with relevant integral data. The data file is available from the IAEA Nuclear Data Section on diskette, cost free. (author) 9 refs, 22 figs, 2 tabs

27 CFR 19.98 - Conveyance of untaxpaid spirits or wines within a distilled spirits plant.

Science.gov (United States)

2010-04-01

... spirits or wines within a distilled spirits plant. 19.98 Section 19.98 Alcohol, Tobacco Products and... PLANTS Administrative and Miscellaneous Provisions Conveyance of Spirits Or Wines on Plant Premises § 19.98 Conveyance of untaxpaid spirits or wines within a distilled spirits plant. Untaxpaid spirits or...

Psalm 98: Sing 'n nuwe lied tot lof van die Koning, Jahwe

African Journals Online (AJOL)

Psalm 98: Sing 'n nuwe lied tot lof van die Koning, Jahwe. W S Prinsloo. Universiteit van Pretoria. Abstract. Sing a new song in praise of the king, Yahweh. This article surveys the problems of interpreting Psalm. 98. The chief problems are those concerned with determining the Gattung, the redactional history, strophic ...

March-april 98, DSIN's operations

International Nuclear Information System (INIS)

Anon.

1998-01-01

This article reviews the different activities of the department of the safety of nuclear installations (DSIN) during march and april 98. For these 2 months 17 incidents happened and were classified on the first level of the international nuclear event scale (INES). 14 incidents occurred in nuclear power plants and 3 in other nuclear installations. The causes, the consequences and the evolution of each incident are thoroughly described. The activities of the inspection teams are reported, about 100 inspections have been performed. As for international cooperation the major events are reviewed. 14 certificates concerning nuclear transport have been issued. (A.C.)

Worldwide natural gas vehicles become reality. World conference for natural gas vehicles HGV`98 in Cologne; Erdgasfahrzeuge werden weltweit Realitaet. Weltkonferenz fuer Erdgasfahrzeuge NGV`98 in Koeln

Energy Technology Data Exchange (ETDEWEB)

Ganser, B. [Rhenag Rheinische Energie AG, Koeln (Germany)

1998-07-01

The 6th World Conference for natural gas vehicles (NGV `98) which was held from May 26th-28th, 1998 in Cologne under the patronage of the Federal Environment Minister Dr. Angela Merkel, lead more than 1000 participants from all over the world to the Cathedral City. The conference, accompanied by an exhibition at which 65 exhibitors showed the newest trends in the vehicle- and filling station technology, was made use of by more than 2000 visitors to inform themselves about the latest technical developments. With this extremely positive resonance of visitors for the conference and trade exhibition, the NGV `98 so far is worldwide the largest event on alternative vehicle drivers. (orig.) [Deutsch] Die 6. Weltkonferenz fuer Erdgasfahrzeuge (NGV `98), die vom 26. bis 28. Maerz 1998 in Koeln unter der Schirmherrschaft von Bundesumweltministerin Dr. Angela Merkel stattfand, fuehrte mehr als 1000 Teilnehmer aus aller Welt in die Domstadt. Die konferenzbegleitende Ausstellung, auf der 65 Aussteller die neuesten Trends in der Fahrzeug- und Tankstellentechnik zeigten, wurde von den mehr als 2000 Besuchern genutzt, um sich ueber die aktuellen technischen Entwicklungen zu informieren. Mit dieser aeusserst positiven Besucherresonanz von Konferenz und Fachausstellung ist die NGV `98 weltweit die bisher groesste Veranstaltung ueber alternative Fahrzeugantriebe. (orig.)

Pinwheel Nebula around WR 98a.

Science.gov (United States)

Monnier; Tuthill; Danchi

1999-11-10

We present the first near-infrared images of the dusty Wolf-Rayet star WR 98a. Aperture-masking interferometry has been utilized to recover images at the diffraction limit of the Keck I telescope, less, similar50 mas at 2.2 µm. Multiepoch observations spanning about 1 yr have resolved the dust shell into a "pinwheel" nebula, the second example of a new class of dust shell first discovered around WR 104 by Tuthill, Monnier, & Danchi. Interpreting the collimated dust outflow in terms of an interacting winds model, the binary orbital parameters and apparent wind speed are derived: a period of 565+/-50 days, a viewing angle of 35&j0;+/-6 degrees from the pole, and a wind speed of 99+/-23 mas yr-1. This period is consistent with a possible approximately 588 day periodicity in the infrared light curve, linking the photometric variation to the binary orbit. Important implications for binary stellar evolution are discussed by identifying WR 104 and WR 98a as members of a class of massive, short-period binaries whose orbits were circularized during a previous red supergiant phase. The current component separation in each system is similar to the diameter of a red supergiant, which indicates that the supergiant phase was likely terminated by Roche lobe overflow, leading to the present Wolf-Rayet stage.

40 CFR 98.410 - Definition of the source category.

Science.gov (United States)

2010-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Industrial Greenhouse Gases § 98.410 Definition of the source category. (a) The industrial gas supplier source category consists of any facility that...

Knock-on electrons in WA98 silicon drift detector

International Nuclear Information System (INIS)

Eliseev, S.

1997-01-01

Silicon Drift Detector is used to estimate production of knock-on electrons created by passage of 158 GeV /u fully stripped Pb ion through thick lead target. Analysed data were collected in 1995 during Pb+Pb run in WA98 heavy ion experiment at CERN SPS. Information from WA98 Cherenkov beam counter makes it possible to classify events according to number of additional Pb ions which have during detector's read-out time passed through the target without nuclear interaction. Events with one and none pile-up ion are used for statistical separation of knock-on electrons from all detected charged particles. Resulting inclusive spectra of knock-on electrons are compared with GRANT simulations and good agreement is found. (author)

Suur 'Alternatsioon 98' / Tiiu Leis, Al Paldrok

Index Scriptorium Estoniae

Leis, Tiiu

1998-01-01

Kaheosalise Pärnu kultuuriürituse 'Alternatsioon 98' tutvustus: 8.-9. mail kujutav-, video- ja tegevuskunst; 5.-6. juunil muusika, tants, sport, mood. 8. mai: punkansambli 'Kurjam' kontsert, avatakse näitused 'Alternatsioon 2' Soolalaos, Tallinnas keelatud 'Eesti Vabariik 80' ja Taave Tuutma 'Rikaste toetamise fond', performance'id Rüütli tänaval; 9. mai: seksuaalvähemuste ja teiste protestimarss.

28 CFR 16.98 - Exemption of the Drug Enforcement Administration (DEA)-limited access.

Science.gov (United States)

2010-07-01

... Administration (DEA)-limited access. 16.98 Section 16.98 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION... Exemption of the Drug Enforcement Administration (DEA)—limited access. (a) The following systems of records.../Diversion Analysis and Detection System (ARCOS/DADS) (Justice/DEA-003) (2) Controlled Substances Act...

40 CFR 98.184 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... Instrumental Determination of Carbon, Hydrogen, and Nitrogen in Laboratory Samples of Coal (incorporated by... Determination of Carbon in Refractory and Reactive Metals and Their Alloys (incorporated by reference, see § 98...

Study of the potentiometric properties of spinel-type manganese oxide doped with gallium and anions Ga0.02Mn1.98O3.98X0.02 (X = S2− and F−) as selective sensor for lithium ion

International Nuclear Information System (INIS)

David-Parra, Diego N.; Bocchi, Nerilso; Teixeira, Marcos F.S.

2015-01-01

Highlights: • Investigated the influence of doping agents on the potentiometric response • Reduction of the unit cell size affected directly in the potentiometric performance of the electrode • Sensor performance increased in the order: Ga 0.02 Mn 1.98 O 4 > Ga 0.02 Mn 1.98 O 3.98 S 0.02 > Ga 0.02 Mn 1.98 O 3.98 F 0.02 . - Abstract: This paper describes the development of a selective lithium ion sensor based on spinel-type manganese oxide doped with gallium and anions (Ga 0.02 Mn 1.98 O 3.98 X 0.02 , where X = S 2− and F − ). Investigation was made of the influence of cationic and/or anionic doping agents on the potentiometric response of the sensor. Experimental parameters evaluated included the effect of the lithium concentration on activation of the sensor by cyclic voltammetry, the pH of the electrolyte solution, and the selectivity towards Li + compared to other alkali and alkaline-earth metal ions. There was an important influence of the unit cell size of the material on the linear range, detection limit, and selectivity of the sensor. Reduction in the size of the tunnel for insertion of the lithium in the porous structure of the oxide directly affected the potentiometric performance of the electrode. Sensor performance increased in the order: Ga 0.02 Mn 1.98 O 4 > Ga 0.02 Mn 1.98 O 3.98 S 0.02 > Ga 0.02 Mn 1.98 O 3.98 F 0.02 . The observed super-Nernstian response could be explained by a mixed potential arising from two equilibria (redox and ion exchange) in the spinel-type manganese oxide. Sensitivity and the influence of pH on the electrode response were directly related to the doping agents present in the oxide structure

40 CFR 98.423 - Calculating CO2 supply.

Science.gov (United States)

2010-07-01

... 98.423 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... quarterly the mass of CO2 in a CO2 stream in metric tons, prior to any subsequent purification, processing... stream in metric tons, prior to any subsequent purification, processing, or compressing, by multiplying...

34 CFR 98.4 - Protection of students' privacy in examination, testing, or treatment.

Science.gov (United States)

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Protection of students' privacy in examination, testing, or treatment. 98.4 Section 98.4 Education Office of the Secretary, Department of Education STUDENT... are not directly related to academic instruction and that is designed to affect behavioral, emotional...

In-beam studies of {sup 98}Cd and {sup 102}Sn

Energy Technology Data Exchange (ETDEWEB)

Lipoglavsek, M. [Uppsala Univ. (Sweden)]|[J. Stefan Institute, Ljubljana (Slovenia); Gorska, M.; Schubart, R. [GSI, Darmstadt (Germany)] [and others

1996-12-31

For the first time excited states of the neutron deficient nuclei {sup 98}Cd and {sup 102}Sn were identified using in-beam spectroscopy following fusion evaporation reactions. Half lives of long lived isomeric states in both nuclei were also measured. Due to very low cross sections for producing {sup 98}Cd and {sup 102}Sn with stable beams and targets, a special detector setup utilizing NORDBALL ancillary detectors and a recoil catcher device was used. High {gamma}-ray detection efficiency was achieved with two EUROBALL Ge cluster detectors.

40 CFR 98.110 - Definition of the source category.

Science.gov (United States)

2010-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ferroalloy Production § 98.110 Definition of the source category. The ferroalloy production source category consists of any facility that uses pyrometallurgical techniques to produce any of the following metals: ferrochromium, ferromanganese, ferromolybdenum...

Shape coexistence and evolution in 98Sr

Science.gov (United States)

Park, J.; Garnsworthy, A. B.; Krücken, R.; Andreoiu, C.; Ball, G. C.; Bender, P. C.; Chester, A.; Close, A.; Finlay, P.; Garrett, P. E.; Glister, J.; Hackman, G.; Hadinia, B.; Leach, K. G.; Rand, E. T.; Sjue, S.; Starosta, K.; Svensson, C. E.; Tardiff, E.

2016-01-01

Shape coexistence between the strongly deformed ground state and the weakly deformed 02+ state in 98Sr has been a major topic of interest due to the energy difference of 215 keV, which is the smallest in all even-even nuclei. The electric monopole transition strength ρ2(E 0 ) is an important quantity that can relate the deformation difference and the shape mixing between the two 0+ states, which are admixtures of the vibrational (S) and the rotational (D) states in a simple mixing model. In a β -decay spectroscopy experiment, the experimental ρ2(E 0 ) was measured. A value of 0.053(5) is consistent with the previous measurement and was combined with known electric quadrupole transition strengths B (E 2 ) in calculations of a two-state mixing model. Based on a systematic study on neighboring Kr, Zr, and Mo isotopes, the mixing of the 0+ and 2+ states in 98Sr was determined to be 8.6% and 1.3%, respectively, corresponding to deformation parameters βD=0.38 (1 ) and βS=-0.23 (2 ) . These parameters reproduce experimental transition strengths well except for the 41+→21+ transition, which suggests a smaller D-band deformation for J ≥4 .

Comparative study of cryopreserved bone tissue and tissue preserved in a 98% glycerol solution Estudo comparativo entre o tecido ósseo criopreservado e o conservado em glicerol a 98%

Directory of Open Access Journals (Sweden)

Arlete Mazzini Miranda Giovani

2006-01-01

Full Text Available OBJECTIVE: To compare the bone graft cryopreservation method (at -80ºC with a preservation method using a 98% glycerol solution at room temperature (10ºC-35ºC, by testing the antibacterial and fungal effects of 98% glycerol and comparatively analyzing the observed histological changes resulting from the use of both methods. METHOD: This study was of 30 samples of trabecular bone tissue from 10 patients undergoing total hip arthroplasty. Each femoral head provided 3 samples that were randomized into 3 groups, namely, the control group, the cryopreserved group, and the group preserved in a 98% glycerol at room temperature for 1 year. The samples were submitted to histomorphologic, cell feasibility, and microbiologic analyses. The results were statistically analyzed using the McNemar test, with a statistical significance index of 0.05. RESULTS: Values obtained using the McNemar test to compare probability distributions of histomorphologic variables (mature or lamellar bone, immature bone, and necrosis and cell feasibility (osteoblasts and osteoclasts indicated that there is no difference between the distributions of variables under the 3 experimental conditions. Microbiological analysis of the 98% glycerol solution and bone fragments from samples stored for 1 year at room temperature did not show bacterial or fungal growth. The histological and microbiological investigation were performed at 2 different time points: immediately after the sample processing and after 1 year. CONCLUSION: The method used to preserve bone grafts kept in 98% glycerol at room temperature (10ºC-35ºC was similar to cryopreservation in terms of bone matrix preservation; no bacteria or fungi were found in the samples.OBJETIVO: Comparar o método da criopreservação de enxertos ósseos (- 80º C com o da conservação em glicerol a 98% em temperatura ambiente (10º C a 35º C, testando os efeitos antibacterianos e antifúngicos do glicerol a 98% e analisando

Negative Impact of Article 98 Sanctions in the Western Hemisphere

National Research Council Canada - National Science Library

Ruiz, Robert D

2007-01-01

... (SAOs) have been established; countries not signing an Article 98 agreement are subject to security assistance sanctions, to include the loss of International Military Education and Training (IMET...

Problems of Chernobyl. Materials of International scientific and practical conference 'Shelter-98'; Problemi Chornobilya. Materyiali Myizhnarodnoyi Naukovo-Praktichnoyi Konferentsyiyi 'Ukrittya-98'

Energy Technology Data Exchange (ETDEWEB)

Klyuchnikov, O O [eds.

1999-07-01

These transactions contain materials of International Scientific and Practical Conference 'Shelter-98', which was held 27-30 November 1998 in Slavutich. They describe the results of the research work of the specialists from Ukraine, neighborhood and far foreign counties. The results, targeted at solving the problems of converting the Shelter Object into oncologically safe state.

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

Science.gov (United States)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- The U.S. Lab Destiny rests in the payload bay of Space Shuttle Atlantis. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

40 CFR 98.164 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... Methods for Instrumental Determination of Carbon, Hydrogen, and Nitrogen in Petroleum Products and... Determination of Carbon, Hydrogen, and Nitrogen in Laboratory Samples of Coal (incorporated by reference, see... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Hydrogen Production § 98.164 Monitoring and QA/QC requirements...

Structure of a tropomyosin N-terminal fragment at 0.98 Å resolution

International Nuclear Information System (INIS)

Meshcheryakov, Vladimir A.; Krieger, Inna; Kostyukova, Alla S.; Samatey, Fadel A.

2011-01-01

The crystal structure of the N-terminal fragment of the short nonmuscle α-tropomyosin has been determined at a resolution of 0.98 Å. Tropomyosin (TM) is an elongated two-chain protein that binds along actin filaments. Important binding sites are localized in the N-terminus of tropomyosin. The structure of the N-terminus of the long muscle α-TM has been solved by both NMR and X-ray crystallography. Only the NMR structure of the N-terminus of the short nonmuscle α-TM is available. Here, the crystal structure of the N-terminus of the short nonmuscle α-TM (αTm1bZip) at a resolution of 0.98 Å is reported, which was solved from crystals belonging to space group P3 1 with unit-cell parameters a = b = 33.00, c = 52.03 Å, α = β = 90, γ = 120°. The first five N-terminal residues are flexible and residues 6–35 form an α-helical coiled coil. The overall fold and the secondary structure of the crystal structure of αTM1bZip are highly similar to the NMR structure and the atomic coordinates of the corresponding C α atoms between the two structures superimpose with a root-mean-square deviation of 0.60 Å. The crystal structure validates the NMR structure, with the positions of the side chains being determined precisely in our structure

Structure of a tropomyosin N-terminal fragment at 0.98 Å resolution

Energy Technology Data Exchange (ETDEWEB)

Meshcheryakov, Vladimir A. [Okinawa Institute of Science and Technology, Okinawa (Japan); Krieger, Inna [Texas A& M University, College Station, Texas (United States); Kostyukova, Alla S. [Robert Wood Johnson Medical School, Piscataway, New Jersey (United States); Samatey, Fadel A., E-mail: f.a.samatey@oist.jp [Okinawa Institute of Science and Technology, Okinawa (Japan)

2011-09-01

The crystal structure of the N-terminal fragment of the short nonmuscle α-tropomyosin has been determined at a resolution of 0.98 Å. Tropomyosin (TM) is an elongated two-chain protein that binds along actin filaments. Important binding sites are localized in the N-terminus of tropomyosin. The structure of the N-terminus of the long muscle α-TM has been solved by both NMR and X-ray crystallography. Only the NMR structure of the N-terminus of the short nonmuscle α-TM is available. Here, the crystal structure of the N-terminus of the short nonmuscle α-TM (αTm1bZip) at a resolution of 0.98 Å is reported, which was solved from crystals belonging to space group P3{sub 1} with unit-cell parameters a = b = 33.00, c = 52.03 Å, α = β = 90, γ = 120°. The first five N-terminal residues are flexible and residues 6–35 form an α-helical coiled coil. The overall fold and the secondary structure of the crystal structure of αTM1bZip are highly similar to the NMR structure and the atomic coordinates of the corresponding C{sup α} atoms between the two structures superimpose with a root-mean-square deviation of 0.60 Å. The crystal structure validates the NMR structure, with the positions of the side chains being determined precisely in our structure.

CLUJ-NAPOCA PRECIPITATION FORECAST USING WSR-98D DOPPLER RADAR

Directory of Open Access Journals (Sweden)

Narcis MAIER

2011-11-01

Full Text Available CLUJ-NAPOCA precipitation forecast using WSR-98D Doppler radar. Forecasting inundations requires accurate spatial and temporal estimation of rainfalls in an area. Depending on the Z-R relationship (reflectivity-precipitation rate, the thresholds, maximum reflectivity data processing, VIL, cloud height or speed, provided by the WSR-98D affects the estimated precipitation used in the prediction of inundations. How much precipitation receives a watershed during an extreme event and what response will result depends on the basin hydrographic characteristics. A study of summer weather events between the years 2004-2008 and a new method in establishing relations between the radar estimated and recorded precipitations led to the determination of new relations between them which will balance the connections between them.

Recent results from the WA98 experiment

International Nuclear Information System (INIS)

Peitzmann, T.; Aggarwal, M.M.; Agnihotri, A.; Ahammed, Z.; Angelis, A.L.S.; Antonenko, V.; Arefiev, V.; Astakhov, V.; Avdeitchikov, V.; Awes, T.C.; Baba, P.V.K.S.; Badyal, S.K.; Baldine, A.; Barabach, L.; Barlag, C.; Bathe, S.; Batiounia, B.; Bernier, T.; Bhalla, K.B.; Bhatia, V.S.; Blume, C.; Bohne, E.-M.; Bucher, D.; Buijs, A.; Buesching, H.; Carlen, L.; Chalyshev, V.; Chattopadhyay, S.; Cherbatchev, R.; Chujo, T.; Claussen, A.; Das, A.C.; Decowski, M.P.; Delagrange, H.; Djordjadze, V.; Donni, P.; Doubovik, I.; Dutt, S.; Dutta Majumdar, M.R.; El Chenawi, K.; Eliseev, S.; Enosawa, K.; Foka, P.; Fokin, S.; Frolov, V.; Ganti, M.S.; Garpman, S.; Gavrishchuk, O.; Geurts, F.J.M.; Ghosh, T.K.; Glasow, R.; Gupta, S.K.; Guskov, B.; Gustafsson, H.A.; Gutbrod, H.H.; Higuchi, R.; Hrivnacova, I.; Ippolitov, M.; Kalechofsky, H.; Kamermans, R.; Kampert, K.-H.; Karadjev, K.; Karpio, K.; Kato, S.; Kim, H.; Kolb, B.W.; Kosarev, I.; Koutcheryaev, I.; Kugler, A.; Kulinich, P.; Kurata, M.; Kurita, K.; Kuzmin, N.; Langbein, I.; Lebedev, A.; Lee, Y.Y.; Loehner, H.; Luquin, L.; Mahapatra, D.P.; Manko, V.; Martin, M.; Martinez, G.; Maximov, A.; Mehdiyev, R.; Mgebrichvili, G.; Miake, Y.; Mikhalev, D.; Mir, Md.F.; Mishra, G.C.; Miyamoto, Y.; Mohanty, B.; Morrison, D.; Mukhopadhyay, D.S.; Myalkovski, V.; Naef, H.; Nandi, B.K.; Nayak, S.K.; Nayak, T.K.; Neumaier, S.; Nianine, A.; Nikitine, V.; Nikolaev, S.; Nilsson, P.; Nishimura, S.; Nomokonov, P.; Nystrand, J.; Obenshain, F.E.; Oskarsson, A.; Otterlund, I.; Pachr, M.; Parfenov, A.; Pavliouk, S.; Petracek, V.; Plasil, F.; Pinganaud, W.; Purschke, M.L.; Raeven, B.; Rak, J.; Raniwala, R.; Raniwala, S.; Ramamurthy, V.S.; Rao, N.K.; Retiere, F.; Reygers, K.; Roland, G.; Rosselet, L.; Roufanov, I.; Roy, C.; Rubio, J.M.; Sako, H.; Sambyal, S.S.; Santo, R.; Sato, S.; Schlagheck, H.; Schmidt, H.-R.; Schutz, Y.; Shabratova, G.; Shah, T.H.; Sibiriak, I.; Siemiarczuk, T.; Silvermyr, D.; Sinha, B.C.; Slavine, N.; Soederstroem, K.; Solomey, N.; Soerensen, S.P.; Stankus, P.; Stefanek, G.; Steinberg, P.; Stenlund, E.; Sumbera, M.; Svensson, T.; Trivedi, M.D.; Tsvetkov, A.; Tykarski, L.; Urbahn, J.; Pijll, E.C.V.D.; Eijndhoven, N.V.; Nieuwenhuizen, G.J.V.; Vinogradov, A.; Viyogi, Y.P.; Vodopianov, A.; Voeroes, S.; Wyslouch, B.; Yagi, K.; Yokota, Y.; Young, G.R.

1999-01-01

Recent results of the WA98 experiment with Pb induced reactions at 158. A GeV are presented. The scaling properties of the transverse energy and the charged particle multiplicity at midrapidity with the number of participants is studied. Neutral pion spectra are compared to hydrodynamical parameterizations. The analysis of collective flow at target rapidity and at midrapidity is presented. The status of the study of direct photons and the search for isospin fluctuations is discussed

MicroRNA-98 rescues proliferation and alleviates ox-LDL-induced apoptosis in HUVECs by targeting LOX-1

Science.gov (United States)

Chen, Zhibo; Wang, Mian; He, Qiong; Li, Zilun; Zhao, Yang; Wang, Wenjian; Ma, Jieyi; Li, Yongxin; Chang, Guangqi

2017-01-01

Oxidized low-density lipoprotein (ox-LDL) is a major and critical mediator of atherosclerosis, and the underlying mechanism is thought to involve the ox-LDL-induced dysfunction of endothelial cells (ECs). MicroRNAs (miRNAs), which are a group of small non-coding RNA molecules that post-transcriptionally regulate the expression of target genes, have been associated with diverse cellular functions and the pathogenesis of various diseases, including atherosclerosis. miRNA-98 (miR-98) has been demonstrated to be involved in the regulation of cellular apoptosis; however, the role of miR-98 in ox-LDL-induced dysfunction of ECs and atherosclerosis has yet to be elucidated. Therefore, the present study aimed to investigate the role of miR-98 in ox-LDL-induced dysfunction of ECs and the underlying mechanism. It was demonstrated that miR-98 expression was markedly downregulated in ox-LDL-treated human umbilical vein ECs (HUVECs) and that miR-98 promoted the proliferation and alleviated apoptosis of HUVECs exposed to ox-LDL. In addition, the results demonstrated that lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) was a direct target of miR-98 in HUVECs, as indicated by a luciferase assay. The results of the present study suggested that miR-98 may inhibit the uptake of toxic ox-LDL, maintain HUVEC proliferation and protect HUVECs against apoptosis via the suppression of LOX-1. PMID:28565756

High glucose concentration induces endothelial cell proliferation by regulating cyclin-D2-related miR-98.

Science.gov (United States)

Li, Xin-Xin; Liu, Yue-Mei; Li, You-Jie; Xie, Ning; Yan, Yun-Fei; Chi, Yong-Liang; Zhou, Ling; Xie, Shu-Yang; Wang, Ping-Yu

2016-06-01

Cyclin D2 is involved in the pathology of vascular complications of type 2 diabetes mellitus (T2DM). This study investigated the role of cyclin-D2-regulated miRNAs in endothelial cell proliferation of T2DM. Results showed that higher glucose concentration (4.5 g/l) significantly promoted the proliferation of rat aortic endothelial cells (RAOECs), and significantly increased the expression of cyclin D2 and phosphorylation of retinoblastoma 1 (p-RB1) in RAOECs compared with those under low glucose concentration. The cyclin D2-3' untranslated region is targeted by miR-98, as demonstrated by miRNA analysis software. Western blot also confirmed that cyclin D2 and p-RB1 expression was regulated by miR-98. The results indicated that miR-98 treatment can induce RAOEC apoptosis. The suppression of RAOEC growth by miR-98 might be related to regulation of Bcl-2, Bax and Caspase 9 expression. Furthermore, the expression levels of miR-98 decreased in 4.5 g/l glucose-treated cells compared with those treated by low glucose concentration. Similarly, the expression of miR-98 significantly decreased in aortas of established streptozotocin (STZ)-induced diabetic rat model compared with that in control rats; but cyclin D2 and p-RB1 levels remarkably increased in aortas of STZ-induced diabetic rats compared with those in healthy control rats. In conclusion, this study demonstrated that high glucose concentration induces cyclin D2 up-regulation and miR-98 down-regulation in the RAOECs. By regulating cyclin D2, miR-98 can inhibit human endothelial cell growth, thereby providing novel therapeutic targets for vascular complication of T2DM. © 2016 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

40 CFR 98.394 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Monitoring and QA/QC requirements. 98... by a consensus-based standards organization exists, such a method shall be used. Consensus-based... (NAESB). (ii) Where no appropriate standard method developed by a consensus-based standards organization...

40 CFR 98.424 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Monitoring and QA/QC requirements. 98... published by a consensus-based standards organization if such a method exists. Consensus-based standards...). (ii) Where no appropriate standard method developed by a consensus-based standards organization exists...

40 CFR 98.65 - Procedures for estimating missing data.

Science.gov (United States)

2010-07-01

... factor (1.6 metric tons CO2/metric ton aluminum produced). MPp = Metal production from prebake process... produced). MPs = Metal production from Sderberg process (metric tons Al). (b) For other parameters, use the... PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Aluminum Production § 98.65 Procedures for...

40 CFR 98.364 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... by Gas Chromatography (incorporated by reference see § 98.7). All gas composition monitors shall be calibrated prior to the first reporting year for biogas methane and carbon dioxide content using ASTM D1946... composition, temperature, and pressure measurements. These procedures include, but are not limited to...

40 CFR 98.360 - Definition of the source category.

Science.gov (United States)

2010-07-01

... this rule. (b) A manure management system (MMS) is a system that stabilizes and/or stores livestock... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Manure Management § 98.360 Definition of the source category. (a) This source category consists of livestock facilities with manure management systems that emit 25...

Triaxial energy relation to describe rotational band in 98-112Ru nuclei

International Nuclear Information System (INIS)

Singh, Yuvraj; Gupta, K.K.; Bihari, Chhail; Varshney, A.K.; Varshney, Mani; Singh, M.; Gupta, D.K.

2010-01-01

In a broader perspective rotation vibration coupling parameter (b) is considered changing with the change in excitation energy (ε 1 ) and is evaluated on fitting experimental energy for 98-112 Ru isotopes in the frame work of general asymmetric rotor model. The moment of inertia parameter (a), common to yrast and quasi-γ band, is calculated from deformation parameter (β) using general empirical relation. The present work is undertaken to suggest some suitable equation for the trajectories which are similar in shape in 98-112 Ru nuclei

9 CFR 98.10a - Embryos from sheep in regions other than Australia, Canada, and New Zealand.

Science.gov (United States)

2010-01-01

... than Australia, Canada, and New Zealand. 98.10a Section 98.10a Animals and Animal Products ANIMAL AND... Asses § 98.10a Embryos from sheep in regions other than Australia, Canada, and New Zealand. (a) Except for embryos from sheep in Australia, Canada, or New Zealand, embryos from sheep may only be imported...

40 CFR 98.54 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... accounting purposes. (d) You must conduct all required performance tests according to the methods in § 98.54... requirements. (a) You must conduct a new performance test and calculate a new facility-specific emissions...) Conduct the performance test annually. (2) Conduct the performance test when your adipic acid production...

40 CFR 98.314 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... requirements. (a) You must measure your consumption of calcined petroleum coke using plant instruments used for.... Alternatively, facilities can measure monthly carbon contents of the petroleum coke using ASTM D3176-89... Nitrogen in Laboratory Samples of Coal (incorporated by reference, see § 98.7). (d) For quality assurance...

40 CFR 98.144 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Monitoring and QA/QC requirements. 98... fraction for each carbonate consumed based on sampling and chemical analysis using an industry consensus... testing method published by an industry consensus standards organization (e.g., ASTM, ASME, API, etc.). ...

40 CFR 98.404 - Monitoring and QA/QC requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Monitoring and QA/QC requirements. 98... published by a consensus-based standards organization exists, such a method shall be used. Consensus-based... (NAESB). (ii) Where no appropriate standard method developed by a consensus-based standards organization...

40 CFR 98.405 - Procedures for estimating missing data.

Science.gov (United States)

2010-07-01

... meter malfunctions), a substitute data value for the missing quantity measurement must be used in the... period for any reason, the reporter shall use either its delivering pipeline measurements or the default... § 98.405 Procedures for estimating missing data. (a) Whenever a quality-assured value of the quantity...

Annual report 1997-98

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

Research and development and other activities of the various constituent units of the Department of Atomic Energy (DAE) and also of the institutions financially aided by DAE during the year 1997-98 are reported. The various constituent units of DAE consist of nuclear research centres, nuclear power, fuel reprocessing and heavy water plants, nuclear fuel fabrication facilities, electronic and instrumentation production organisations, atomic mineral processing units and other nuclear installations. The activities of DAE cover the whole gamut of nuclear fuel cycle, research and development in nuclear science and reactor technology, applications of radiation and radioisotopes, radiation protection, environmental aspects, research and development in front line areas such as robotics, lasers, parallel processing etc.. These activities are described under the headings: introduction, the year at a glance, nuclear power and associated programmes, research and development programmes-I and II, public sector undertakings, service organisations. Other activities covered include international relations, IX plan formulation, management services, public awareness, computational facilities, library and information services etc.. The report also gives details about the organisational and administrative aspects of the DAE figs., ills.

Annual report 1997-98

International Nuclear Information System (INIS)

1998-01-01

Research and development and other activities of the various constituent units of the Department of Atomic Energy (DAE) and also of the institutions financially aided by DAE during the year 1997-98 are reported. The various constituent units of DAE consist of nuclear research centres, nuclear power, fuel reprocessing and heavy water plants, nuclear fuel fabrication facilities, electronic and instrumentation production organisations, atomic mineral processing units and other nuclear installations. The activities of DAE cover the whole gamut of nuclear fuel cycle, research and development in nuclear science and reactor technology, applications of radiation and radioisotopes, radiation protection, environmental aspects, research and development in front line areas such as robotics, lasers, parallel processing etc.. These activities are described under the headings: introduction, the year at a glance, nuclear power and associated programmes, research and development programmes-I and II, public sector undertakings, service organisations. Other activities covered include international relations, IX plan formulation, management services, public awareness, computational facilities, library and information services etc.. The report also gives details about the organisational and administrative aspects of the DAE

Belöning och motivation

OpenAIRE

Blomqvist, Johnny

2015-01-01

Många företag använder sig av belöningssystem för att hålla kvar den nuvarande personalen och för att motivera personalen till ett bättre resultat i framtiden. För att ett belöningssystem skall fungera måste personalen vara motiverade. Syftet med detta arbete är att utreda vad personalen i några företag på Kimitoön anser om belöning och betydelsen av belöning i arbetet. I undersökningen utreder jag även motivationens betydelse i arbetet och vilken typ av belöning som motiverar på längre si...

The «myth of 98» in Spanish culture | El «mito del 98» en la cultura española

Directory of Open Access Journals (Sweden)

Francisco Sevillano Calero

2004-12-01

Full Text Available With the commemoration of the «Disaster» of 1898, the dramatic vision of Spanish history was put aside and replaced by an updated image of «normality» among European nations. However, criticism of the «myth of 98» has generated certain revisionist excesses, especially due to the anachronistic «external reading» of that period of the past. Thus, critics have considered the terms «modernism» and «symbolism» in Spanish culture in opposition to the expression «generation of 1898». The idea put forward in this article is that the so-called «crisis of the end of the century» in Spain was above all an «experience», perceived as a generational break in the face of modernity. This approach enables Spanish culture to be interpreted «from within» with regard to the collective representation of reality in each historical context. | Con la conmemoración del «Desastre» de 1898 se abandonó la visión dramática de la historia de España por una renovada imagen de «normalidad» entre las naciones europeas. Sin embargo, la crítica del «mito del 98» ha producido ciertos excesos revisionistas, sobre todo por la anacrónica «lectura externa» de aquel pasado. Ello ha ocurrido con la consideración de los términos «modernismo» y «simbolismo» frente a la expresión «generación del 98» en la cultura española. La idea de este trabajo es que la llamada «crisis de fin de siglo» en España fue ante todo una «vivencia», experimentada como ruptura generacional ante la modernidad. Este planteamiento permite interpretar «desde dentro» la cultura española en relación con la representación colectiva de la realidad en cada contexto histórico.

Domain analyses of Usher syndrome causing Clarin-1 and GPR98 protein models.

Science.gov (United States)

Khan, Sehrish Haider; Javed, Muhammad Rizwan; Qasim, Muhammad; Shahzadi, Samar; Jalil, Asma; Rehman, Shahid Ur

2014-01-01

Usher syndrome is an autosomal recessive disorder that causes hearing loss, Retinitis Pigmentosa (RP) and vestibular dysfunction. It is clinically and genetically heterogeneous disorder which is clinically divided into three types i.e. type I, type II and type III. To date, there are about twelve loci and ten identified genes which are associated with Usher syndrome. A mutation in any of these genes e.g. CDH23, CLRN1, GPR98, MYO7A, PCDH15, USH1C, USH1G, USH2A and DFNB31 can result in Usher syndrome or non-syndromic deafness. These genes provide instructions for making proteins that play important roles in normal hearing, balance and vision. Studies have shown that protein structures of only seven genes have been determined experimentally and there are still three genes whose structures are unavailable. These genes are Clarin-1, GPR98 and Usherin. In the absence of an experimentally determined structure, homology modeling and threading often provide a useful 3D model of a protein. Therefore in the current study Clarin-1 and GPR98 proteins have been analyzed for signal peptide, domains and motifs. Clarin-1 protein was found to be without any signal peptide and consists of prokar lipoprotein domain. Clarin-1 is classified within claudin 2 super family and consists of twelve motifs. Whereas, GPR98 has a 29 amino acids long signal peptide and classified within GPCR family 2 having Concanavalin A-like lectin/glucanase superfamily. It was found to be consists of GPS and G protein receptor F2 domains and twenty nine motifs. Their 3D structures have been predicted using I-TASSER server. The model of Clarin-1 showed only α-helix but no beta sheets while model of GPR98 showed both α-helix and β sheets. The predicted structures were then evaluated and validated by MolProbity and Ramachandran plot. The evaluation of the predicted structures showed 78.9% residues of Clarin-1 and 78.9% residues of GPR98 within favored regions. The findings of present study has resulted in the

Gender wage gap in Vietnam 1993 - 98

OpenAIRE

Amy Y.C. Liu

2003-01-01

This paper uses the Vietnam Living Standards Surveys 1992–93 and 1997–98 to examine changes in the gender wage gap. The intertemporal decomposition of Juhn et al. (1991) indicates that changes in observed variables, skill prices and wage inequality have tended to narrow the gap, but the gap effect has tended to widen it, with the net effect being one of little change. This finding is in contrast with that for the EEC but in line with the experience of China. Improving education about equity p...

Spectroscopy of 96-98Ru and neighboring nuclei: shell model calculations and lifetime measurements

International Nuclear Information System (INIS)

Kharraja, B.; Garg, U.; Ghugre, S.S.

1997-01-01

High Spin states in 94,95 Mo, 94-96 Tc, 96-98 Ru and 97,98 Rh were populated via the 65 Cu( 36 S,xpyn) reactions at 142 MeV. Level schemes of these nuclei have been extended up to a spin of J ∼ 20ℎ and an excitation energy of E x ∼12 -14 MeV. Information on the high spin structure for 96 Tc and 98 Rh has been obtained for the first time. Spherical shell model calculations have been performed and compared with the experimental excitation energies. The level structures of the N=51, 52 isotones exhibit single-particle nature even at the highest spins and excitation energies. A fragmentation of intensity into several branches after breaking of the N = 50 core has been observed. There are indications for the onset of collectivity around neutron number N = 53 in this mass region. A sequence of E2 transitions, reminiscent of vibrational degree of freedom, were observed in 98 Ru at spins just above the observed N = 50 core breaking. RDM lifetime measurements have been performed to ascertain the intrinsic structures of these level sequences. (author)

9 CFR 98.38 - Restrictions on the importation of swine semen from the APHIS-defined EU CSF region.

Science.gov (United States)

2010-01-01

... swine semen from the APHIS-defined EU CSF region. 98.38 Section 98.38 Animals and Animal Products ANIMAL... (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMAL EMBRYOS AND ANIMAL SEMEN Certain Animal Semen § 98.38 Restrictions on the importation of swine semen from the APHIS-defined EU CSF region. In...

Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression.

Science.gov (United States)

Pascual-Garcia, Pau; Jeong, Jieun; Capelson, Maya

2014-10-23

The nuclear pore complex is a transport channel embedded in the nuclear envelope and made up of 30 different components termed nucleoporins (Nups). In addition to their classical role in transport, a subset of Nups has a conserved role in the regulation of transcription via direct binding to chromatin. The molecular details of this function remain obscure, and it is unknown how metazoan Nups are recruited to their chromatin locations or what transcription steps they regulate. Here, we demonstrate genome-wide and physical association between Nup98 and histone-modifying complexes MBD-R2/NSL [corrected] and Trx/MLL. Importantly, we identify a requirement for MBD-R2 in recruitment of Nup98 to many of its genomic target sites. Consistent with its interaction with the Trx/MLL complex, Nup98 is shown to be necessary for Hox gene expression in developing fly tissues. These findings introduce roles of Nup98 in epigenetic regulation that may underlie the basis of oncogenicity of Nup98 fusions in leukemia.

Salem 98: A post-plume phase, federal participation exercise

International Nuclear Information System (INIS)

1999-01-01

Salem 98 was the largest nuclear power plant post-plume phase exercise since the 1993 FRMAC-93 exercise at the Fort Calhoun Nuclear Power Plant in Nebraska. Salem 98 was a 3 Day exercise, held on May 5--7, 1998, involving participation by the States of New Jersey and Delaware and associated State and county agencies. Public Service Electric and Gas was the host utility and Salem County the host county. Federal participation included the Nuclear Regulatory Commission, Federal Emergency Management Agency, Department of Energy, Environmental Protection Agency, US department of Agriculture and Department of Health and Human Services. In addition, the American Nuclear Insurers participated, adding a dimension to the exercise not experienced often enough. This was a stand-alone post-plume phase exercise, which took place 2 months after the evaluated plume phase exercise held on March 3, 1998, also including participation by various Federal agencies. This exercise demonstrated the positive working relationship among utility, State, county, and Federal responders in response to a postulated major nuclear power plant emergency with significant offsite consequences

Salem 98: A post-plume phase, federal participation exercise

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-01-01

Salem 98 was the largest nuclear power plant post-plume phase exercise since the 1993 FRMAC-93 exercise at the Fort Calhoun Nuclear Power Plant in Nebraska. Salem 98 was a 3 Day exercise, held on May 5--7, 1998, involving participation by the States of New Jersey and Delaware and associated State and county agencies. Public Service Electric and Gas was the host utility and Salem County the host county. Federal participation included the Nuclear Regulatory Commission, Federal Emergency Management Agency, Department of Energy, Environmental Protection Agency, US department of Agriculture and Department of Health and Human Services. In addition, the American Nuclear Insurers participated, adding a dimension to the exercise not experienced often enough. This was a stand-alone post-plume phase exercise, which took place 2 months after the evaluated plume phase exercise held on March 3, 1998, also including participation by various Federal agencies. This exercise demonstrated the positive working relationship among utility, State, county, and Federal responders in response to a postulated major nuclear power plant emergency with significant offsite consequences.

Surface-water quality, Oneida Reservation and vicinity, Wisconsin, 1997-98

Science.gov (United States)

Schmidt, Morgan A.; Scudder, Barbara C.; Richards, Kevin D.

2000-01-01

Streamwater samples were collected at 19 sites in the vicinity of the Oneida Tribe of Indians of Wisconsin Reservation. Samples were collected during 5 sampling periods in 1997-98. Field measurements were made and samples were analyzed for nutrients, suspended sediment, major ions, and pesticides.

Brucella Intracellular Life Relies on the Transmembrane Protein CD98 Heavy Chain.

Science.gov (United States)

Keriel, Anne; Botella, Eric; Estrach, Soline; Bragagnolo, Gabriel; Vergunst, Annette C; Feral, Chloe C; O'Callaghan, David

2015-06-01

Brucella are intracellular bacterial pathogens that use a type IV secretion system (T4SS) to escape host defenses and create a niche in which they can multiply. Although the importance of Brucella T4SS is clear, little is known about its interactions with host cell structures. In this study, we identified the eukaryotic protein CD98hc as a partner for Brucella T4SS subunit VirB2. This transmembrane glycoprotein is involved in amino acid transport, modulation of integrin signaling, and cell-to-cell fusion. Knockdown of CD98hc expression in HeLa cells demonstrated that it is essential for Brucella infection. Using knockout dermal fibroblasts, we confirmed its role for Brucella but found that it is not required for Salmonella infection. CD98hc transiently accumulates around the bacteria during the early phases of infection and is required for both optimal bacterial uptake and intracellular multiplication of Brucella. These results provide new insights into the complex interplay between Brucella and its host. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

The BEL information extraction workflow (BELIEF): evaluation in the BioCreative V BEL and IAT track.

Science.gov (United States)

Madan, Sumit; Hodapp, Sven; Senger, Philipp; Ansari, Sam; Szostak, Justyna; Hoeng, Julia; Peitsch, Manuel; Fluck, Juliane

2016-01-01

Network-based approaches have become extremely important in systems biology to achieve a better understanding of biological mechanisms. For network representation, the Biological Expression Language (BEL) is well designed to collate findings from the scientific literature into biological network models. To facilitate encoding and biocuration of such findings in BEL, a BEL Information Extraction Workflow (BELIEF) was developed. BELIEF provides a web-based curation interface, the BELIEF Dashboard, that incorporates text mining techniques to support the biocurator in the generation of BEL networks. The underlying UIMA-based text mining pipeline (BELIEF Pipeline) uses several named entity recognition processes and relationship extraction methods to detect concepts and BEL relationships in literature. The BELIEF Dashboard allows easy curation of the automatically generated BEL statements and their context annotations. Resulting BEL statements and their context annotations can be syntactically and semantically verified to ensure consistency in the BEL network. In summary, the workflow supports experts in different stages of systems biology network building. Based on the BioCreative V BEL track evaluation, we show that the BELIEF Pipeline automatically extracts relationships with an F-score of 36.4% and fully correct statements can be obtained with an F-score of 30.8%. Participation in the BioCreative V Interactive task (IAT) track with BELIEF revealed a systems usability scale (SUS) of 67. Considering the complexity of the task for new users-learning BEL, working with a completely new interface, and performing complex curation-a score so close to the overall SUS average highlights the usability of BELIEF.Database URL: BELIEF is available at http://www.scaiview.com/belief/. © The Author(s) 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

STS-98 Destiny in Atlantis's payload bay

Science.gov (United States)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- The U.S. Laboratory Destiny rests once again in Atlantis'''s payload bay, at Launch Pad 39A. Closing of the payload bay doors is imminent. Destiny, a key element in the construction of the International Space Station, is 28 feet long and weighs 16 tons. This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will be launched Feb. 7 on STS-98, the seventh construction flight to the ISS.

29 CFR 98.800 - What are the causes for debarment?

Science.gov (United States)

2010-07-01

... business integrity or business honesty that seriously and directly affects your present responsibility; (b... public agreements or transactions; (2) A history of failure to perform or of unsatisfactory performance..., 1995; (2) Knowingly doing business with an ineligible person, except as permitted under § 98.120; (3...

Differential recognition and hydrolysis of host carbohydrate antigens by Streptococcus pneumoniae family 98 glycoside hydrolases.

Science.gov (United States)

Higgins, Melanie A; Whitworth, Garrett E; El Warry, Nahida; Randriantsoa, Mialy; Samain, Eric; Burke, Robert D; Vocadlo, David J; Boraston, Alisdair B

2009-09-18

The presence of a fucose utilization operon in the Streptococcus pneumoniae genome and its established importance in virulence indicates a reliance of this bacterium on the harvesting of host fucose-containing glycans. The identities of these glycans, however, and how they are harvested is presently unknown. The biochemical and high resolution x-ray crystallographic analysis of two family 98 glycoside hydrolases (GH98s) from distinctive forms of the fucose utilization operon that originate from different S. pneumoniae strains reveal that one enzyme, the predominant type among pneumococcal isolates, has a unique endo-beta-galactosidase activity on the LewisY antigen. Altered active site topography in the other species of GH98 enzyme tune its endo-beta-galactosidase activity to the blood group A and B antigens. Despite their different specificities, these enzymes, and by extension all family 98 glycoside hydrolases, use an inverting catalytic mechanism. Many bacterial and viral pathogens exploit host carbohydrate antigens for adherence as a precursor to colonization or infection. However, this is the first evidence of bacterial endoglycosidase enzymes that are known to play a role in virulence and are specific for distinct host carbohydrate antigens. The strain-specific distribution of two distinct types of GH98 enzymes further suggests that S. pneumoniae strains may specialize to exploit host-specific antigens that vary from host to host, a factor that may feature in whether a strain is capable of colonizing a host or establishing an invasive infection.

Panorama 98. 16 thematic files

International Nuclear Information System (INIS)

Anon.

1998-01-01

Under the 'Panorama 98' title, the Institut Francais du Petrole (IFP) has organized an international colloquium on the most recent events and the foreseeable perspectives in the domain of hydrocarbons. 16 technical and economical documentation files were given to the participants. This paper presents a synthesis of the content of these files: the oil offer and demand, the worldwide petroleum activity, the recent oil and gas discoveries, the stakes of the oil and gas perspectives in the North Sea, the US renewal in the Gulf of Mexico, the exploitation of heavy and extra-heavy crudes in Venezuela, the Asian oil rise, the limits of oil recovery efficiency, the oil markets, the international overview of the natural gas industry, the perspectives of the LNG market, the recent evolution and the perspectives of the European refining activities, the oil companies in 1997, the future of marketing, the trends of European automotive industry, and the scientific certitudes and uncertainties about urban pollution. (J.S.)

Structural dynamics and interactions of Xeroderma pigmentosum complementation group A (XPA98-210) with damaged DNA.

Science.gov (United States)

Pradhan, Sushmita; Mattaparthi, Venkata Satish Kumar

2017-10-25

Nucleotide excision repair (NER) in higher organisms repair massive DNA abrasions caused by ultraviolet rays, and various mutagens, where Xeroderma pigmentosum group A (XPA) protein is known to be involved in damage recognition step. Any mutations in XPA cause classical Xeroderma pigmentosum disease. The extent to which XPA is required in the NER is still unclear. Here, we present the comparative study on the structural and conformational changes in globular DNA binding domain of XPA 98-210 in DNA bound and DNA free state. Atomistic molecular dynamics simulation was carried out for both XPA 98-210 systems using AMBER force fields. We observed that XPA 98-210 in presence of damaged DNA exhibited more structural changes compared to XPA 98-210 in its free form. When XPA is in contact with DNA, we found marked stability of the complex due to the formation of characteristic longer antiparallel β-sheets consisting mainly lysine residues.

Proceedings of the 8. Mediterranean Conference on Medical and Biological Engineering and Computing (Medicon `98)

Energy Technology Data Exchange (ETDEWEB)

Christofides, Stelios; Pattichis, Constantinos; Schizas, Christos; Keravnou-Papailiou, Elpida; Kaplanis, Prodromos; Spyros, Spyrou; Christodoulides, George; Theodoulou, Yiannis [eds.

1999-12-31

Medicon `98 is the eighth in the series of regional meetings of the International Federation of Medical and Biological Engineering (IFMBE) in the Mediterranean. The goal of Medicon `98 is to provide updated information on the state of the art on medical and biological engineering and computing. Medicon `98 was held in Lemesos, Cyprus, between 14-17 June, 1998. The full papers of the proceedings were published on CD and consisted of 190 invited and submitted papers. A book of abstracts was also published in paper form and was available to all the participants. Twenty seven papers fall within the scope of INIS and are dealing with Nuclear Medicine,Computerized Tomography, Radiology, Radiotherapy, Magnetic Resonance Imaging and Personnel Dosimetry (eds).

Proceedings of the 8. Mediterranean Conference on Medical and Biological Engineering and Computing (Medicon '98)

International Nuclear Information System (INIS)

Christofides, Stelios; Pattichis, Constantinos; Schizas, Christos; Keravnou-Papailiou, Elpida; Kaplanis, Prodromos; Spyros, Spyrou; Christodoulides, George; Theodoulou, Yiannis

1998-01-01

Medicon '98 is the eighth in the series of regional meetings of the International Federation of Medical and Biological Engineering (IFMBE) in the Mediterranean. The goal of Medicon '98 is to provide updated information on the state of the art on medical and biological engineering and computing. Medicon '98 was held in Lemesos, Cyprus, between 14-17 June, 1998. The full papers of the proceedings were published on CD and consisted of 190 invited and submitted papers. A book of abstracts was also published in paper form and was available to all the participants. Twenty seven papers fall within the scope of INIS and are dealing with Nuclear Medicine,Computerized Tomography, Radiology, Radiotherapy, Magnetic Resonance Imaging and Personnel Dosimetry (eds)

OKN-007 decreases free radical levels in a preclinical F98 rat glioma model.

Science.gov (United States)

Coutinho de Souza, Patricia; Smith, Nataliya; Atolagbe, Oluwatomisin; Ziegler, Jadith; Njoku, Charity; Lerner, Megan; Ehrenshaft, Marilyn; Mason, Ronald P; Meek, Bill; Plafker, Scott M; Saunders, Debra; Mamedova, Nadezda; Towner, Rheal A

2015-10-01

Free radicals are associated with glioma tumors. Here, we report on the ability of an anticancer nitrone compound, OKN-007 [Oklahoma Nitrone 007; a disulfonyl derivative of α-phenyl-tert-butyl nitrone (PBN)] to decrease free radical levels in F98 rat gliomas using combined molecular magnetic resonance imaging (mMRI) and immunospin-trapping (IST) methodologies. Free radicals are trapped with the spin-trapping agent, 5,5-dimethyl-1-pyrroline N-oxide (DMPO), to form DMPO macromolecule radical adducts, and then further tagged by immunospin trapping by an antibody against DMPO adducts. In this study, we combined mMRI with a biotin-Gd-DTPA-albumin-based contrast agent for signal detection with the specificity of an antibody for DMPO nitrone adducts (anti-DMPO probe), to detect in vivo free radicals in OKN-007-treated rat F98 gliomas. OKN-007 was found to significantly decrease (P free radical levels detected with an anti-DMPO probe in treated animals compared to untreated rats. Immunoelectron microscopy was used with gold-labeled antibiotin to detect the anti-DMPO probe within the plasma membrane of F98 tumor cells from rats administered anti-DMPO in vivo. OKN-007 was also found to decrease nuclear factor erythroid 2-related factor 2, inducible nitric oxide synthase, 3-nitrotyrosine, and malondialdehyde in ex vivo F98 glioma tissues via immunohistochemistry, as well as decrease 3-nitrotyrosine and malondialdehyde adducts in vitro in F98 cells via ELISA. The results indicate that OKN-007 effectively decreases free radicals associated with glioma tumor growth. Furthermore, this method can potentially be applied toward other types of cancers for the in vivo detection of macromolecular free radicals and the assessment of antioxidants. Copyright © 2015. Published by Elsevier Inc.

98 Etude Comparative du Systeme Phonematique et Tonal des ...

African Journals Online (AJOL)

98. Etude Comparative du Systeme Phonematique et Tonal des. Deux Parlers: Le Yoruba du Nigeria et L'itsa Parle en. Republique du Benin. Ajani Akinwumi Lateef et Ayuba G. Ajibabi http://dx.doi./org/10.4314/ujah.v18i3.5. Résume. En ce début de l'époque ou la mondialisation et la coexistence des peuples dans le ...

MP98, an innovative reactivity control system for LWR and VHTR, tests results on prototypes

International Nuclear Information System (INIS)

Emin, M.; Gagne, J.F.

2005-01-01

MP98' Reactivity Control System is now a technology tested on a real scale prototypes. Demonstrator is working at PWR real conditions (155 bars, 320 degree C), and many accidents configurations could be simulated. This paper presents the technology, describes the demonstrator design and presents some results. Mock up and demonstrator have permitted to optimize the design of MP98' devices to prepare industrialization. (authors)

9 CFR 98.21 - Embryos from sheep in regions other than Australia, Canada, and New Zealand.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Embryos from sheep in regions other than Australia, Canada, and New Zealand. 98.21 Section 98.21 Animals and Animal Products ANIMAL AND... in regions other than Australia, Canada, and New Zealand. Except for embryos from sheep in Australia...

10 Bel 03.pmd

African Journals Online (AJOL)

Owner

2 maart 2009 ... Congo, de missie en de literatuur: Over David van Reybrouck,. J. G. Schoup en Amaat Vyncke. Jacqueline Bel. Jacqueline Bel is als universitair hoofddocent moderne Nederlandse letterkunde verbonden aan de Vrije. Universiteit in Amsterdam. Zij is onder meer gespecialiseerd in Nederlandse en Vlaamse.

Curcumin Inhibits LIN-28A through the Activation of miRNA-98 in the Lung Cancer Cell Line A549.

Science.gov (United States)

Liu, Wei-Lun; Chang, Jia-Ming; Chong, Inn-Wen; Hung, Yi-Li; Chen, Yung-Hsiang; Huang, Wen-Tsung; Kuo, Hsuan-Fu; Hsieh, Chong-Chao; Liu, Po-Len

2017-06-03

Metastasis is common in lung cancer and is associated with poor clinical outcomes and increased mortality. Curcumin is a natural anti-cancer agent that inhibits the metastasis of various cancers by modulating the expression of micro (mi) RNAs such as miR-98, which acts as a tumor suppressor. This study investigated the effect of curcumin on miR-98 expression and in vitro cell line growth and invasiveness in lung cancer. Curcumin treatment enhanced the expression of miR-98 and reduced that of the miR-98 target gene LIN28A as well as matrix metalloproteinase ( MMP ) 2 and MMP9 in vitro and in vivo. MiR-98 overexpression suppressed lung cancer cell migration and invasion by inhibiting LIN28A-induced MMP2 and MMP9 expression. Meanwhile, LIN28A level was downregulated by overexpression of miR-98 mimic. Induction of miR-98 by curcumin treatment suppressed MMP2 and MMP9 by targeting LIN28A. These findings provide insight into the mechanisms by which curcumin suppresses lung cancer cell line growth in vitro and in vivo and invasiveness in vitro.

CD98 Heavy Chain Is a Potent Positive Regulator of CD4+ T Cell Proliferation and Interferon-γ Production In Vivo.

Directory of Open Access Journals (Sweden)

Takeshi Kurihara

Full Text Available Upon their recognition of antigens presented by the MHC, T cell proliferation is vital for clonal expansion and the acquisition of effector functions, which are essential for mounting adaptive immune responses. The CD98 heavy chain (CD98hc, Slc3a2 plays a crucial role in the proliferation of both CD4+ and CD8+ T cells, although it is unclear if CD98hc directly regulates the T cell effector functions that are not linked with T cell proliferation in vivo. Here, we demonstrate that CD98hc is required for both CD4+ T cell proliferation and Th1 functional differentiation. T cell-specific deletion of CD98hc did not affect T cell development in the thymus. CD98hc-deficient CD4+ T cells proliferated in vivo more slowly as compared with control T cells. C57BL/6 mice lacking CD98hc in their CD4+ T cells could not control Leishmania major infections due to lowered IFN-γ production, even with massive CD4+ T cell proliferation. CD98hc-deficient CD4+ T cells exhibited lower IFN-γ production compared with wild-type T cells, even when comparing IFN-γ expression in cells that underwent the same number of cell divisions. Therefore, these data indicate that CD98hc is required for CD4+ T cell expansion and functional Th1 differentiation in vivo, and suggest that CD98hc might be a good target for treating Th1-mediated immune disorders.

Accelerator physics highlights in the 1997/98 SLC run

International Nuclear Information System (INIS)

Assmann, R.W.; Bane, K.L.F.; Barkow, T.

1998-03-01

The authors report various accelerator physics studies and improvements from the 1997/98 run at the Stanford Linear Collider (SLC). In particular, the authors discuss damping-ring lattice diagnostics, changes to the linac set up, fast control for linac rf phase stability, new emittance tuning strategies, wakefield reduction, modifications of the final-focus optics, longitudinal bunch shaping, and a novel spot-size control at the interaction point (IP)

X-ray radiation induced bystander effects of human glioblastoma T98G cells under hypoxia condition

International Nuclear Information System (INIS)

Zhang Jianghong; Jin Yizun; Shao Chunlin; Prise, K.M.

2008-01-01

Non-irradiated bystander human glioblastoma T98G cells were co-cultured (CC) with irradiated cells or treated with conditioned medium (CM) from irradiated cells under hypoxic condition, then micronucleus (MN) of both irradiated cells and bystander cells were measured for the investigation of radiation induced bystander effect and its mechanism. It has been found that the MN yield (Y MN ) of non-irradiated bystander T98G cells is obviously enhanced after the cell co-culture, or CM treatment, but this increment is diminished by free radical scavenger, dimethyl sulfoxide (DMSO). When hypoxic or normoxic T98G cells are treated with CM obtained from irradiated cells under either hypoxic or normoxic condition, the biggest bystander response has been observed in the group of hypoxic by- stander cells treated with CM from irradiated normoxic cells. However, all of these increments of bystander Y MN could be eliminated by aminoguanidine, an iNOS inhibitor. Therefore, under hypoxic condition, free radicals, especially reactive oxygen species and nitric oxide, are involved in the bystander response induced by irradiated T98G cells. (authors)

Update of the BIG 1-98 Trial: where do we stand?

Science.gov (United States)

Joerger, Markus; Thürlimann, Beat

2009-10-01

There is accumulating data on the clinical benefit of aromatase inhibitors in the adjuvant treatment of early-stage breast cancer in postmenopausal women. The Breast International Group (BIG) 1-98 study is a randomized, phase 3, double-blind trial comparing four adjuvant endocrine treatments of 5 years duration in postmenopausal women with hormone-receptor-positive breast cancer: letrozole or tamoxifen monotherapy, sequential treatment with tamoxifen followed by letrozole, or vice versa. This article summarizes data presented at the 2009 St. Gallen early breast cancer conference: an update on the monotherapy arms of the BIG 1-98 study, and results from the sequential treatment arms. Implications for daily practice from BIG 1-98 and from other adjuvant trials will be discussed. Despite cross-over from tamoxifen to letrozole by 25% of the patients after unblinding of the tamoxifen monotherapy arm, the improvement of disease-free survival (HR 0.88, 0.78-0.99, p = 0.03) and time to distant recurrence (HR 0.85, 0.72-1.00, p = 0.05) for letrozole monotherapy as compared to tamoxifen monotherapy remained significant in the intention-to-treat (ITT) analysis. A trend for an overall survival advantage for letrozole was seen in the ITT analysis (HR 0.87, 0.75-1.02, p = 0.08). No statistically significant differences were found for the sequential treatment arms versus letrozole monotherapy, with respect to disease-free survival, time to distant recurrence or overall survival. Cumulative incidence analysis of breast cancer recurrence favors the initiation of adjuvant endocrine treatment with letrozole instead of tamoxifen, especially in patients at higher risk for early recurrence. Similarly, data suggest that patients commenced on letrozole can be switched to tamoxifen after 2 years, if required. The BIG 1-98 study update with median follow up of 76 months confirms a significant reduction in the risk of breast cancer recurrence and a trend towards improved overall survival

STRATEGI PUBLIC RELATIONS KOMNAS PEREMPUAN DALAM MENGKOMUNIKASIKAN “TRAGEDI 98”

Directory of Open Access Journals (Sweden)

Mulia Bahagia Putri Mooduto

2015-11-01

Full Text Available Public Relations Strategy is very important for the organization to achieve its goals. Maintaining the public memory of the rape of women in the tragedy of May 98 became a very important thing to be done by the National Commission for Women. Because, when people have a collective memory, meaning that they have the same goal. Thus, they will do the efforts that all parties supporting their goals. For that, it takes a Public Relations strategy that Komnas Perempuan can maintain public memory. The purpose of this study was to determine the strategy of Public Relations National Commission for Women in maintaining public memory about the rape of women in the tragedy of 98 by using the theoretical basis of the strategic Public Relations based explanation Ronald D. Smith. This study used a qualitative approach with descriptive type. The method used is a case study to conduct in-depth interview to the informant. This study concluded that the Public Relations strategy undertaken by the National Commission on Women is to create programs that involve all public organizations to participate actively from the stage of planning, implementation and evaluation stages.   Strategi Hubungan Masyarakat sangat penting bagi organisasi untuk mencapai tujuannya. Memelihara ingatan publik terhadap pemerkosaan perempuan dalam tragedi 98 Mei menjadi hal yang sangat penting untuk dilakukan oleh Komnas Perempuan. Sebab, saat orang memiliki ingatan kolektif, berarti mereka memiliki tujuan yang sama. Dengan demikian, mereka akan melakukan upaya agar semua pihak mendukung tujuan mereka. Untuk itu dibutuhkan strategi Public Relations agar Komnas Perempuan dapat menjaga memori publik. Tujuan dari penelitian ini adalah untuk mengetahui strategi Public Relations Komisi Nasional Perempuan dalam memelihara memori masyarakat tentang pemerkosaan perempuan dalam tragedi 98 dengan menggunakan dasar teoritis dari penjelasan strategis Public Relations Ronald D. Smith. Penelitian ini

Performance of the CAPRICE98 balloon-borne gas-RICH detector

CERN Document Server

Bergström, D; Carlson, P J; Francke, T; Grinstein, S; Weber, N; Suffert, Martin; Hof, M; Kremer, J; Menn, W; Simon, M; Stephens, S A; Ambriola, M; Bellotti, R; Cafagna, F; Castellano, M G; Ciacio, F; Circella, M; De Marzo, C; Finetti, N; Papini, P; Piccardi, S; Spillantini, P; Bartalucci, S; Ricci, M; Bidoli, V; Casolino, M; De Pascale, M P; Morselli, A; Picozza, P; Sparvoli, R; Barbiellini, Guido; Schiavon, R P; Vacchi, A; Zampa, N; Mitchell, J W; Ormes, J F; Streitmatter, R E; Bravar, U; Stochaj, S J

2001-01-01

A RICH counter using a gas radiator of C/sub 4/F/sub 10/ and a photosensitive MWPC with pad readout has been developed, tested in particle beam at CERN and used in the CAPRICE98 balloon-borne experiment. The MWPC was operated with a TMAE and ethane mixture at atmospheric pressure and used a cathode pad plane to give an unambiguous image of the Cherenkov light. The induced signals in the pad plane were read our using the AMPLEX chip and CRAMS. The good efficiency of the Cherenkov light collection, the efficient detection of the weak signal from single UV photons together with a low noise level in the electronics of the RICH detector, resulted in a large number of detected photoelectrons per event. For beta approximately=1 charge one particles, an average of 12 photoelectrons per event were detected. The reconstructed Cherenkov angle of 50 mrad for a beta approximately=1 particle had a resolution of 1.2 mrad (rms). The RICH was flown with the CAPRICE98 magnetic spectrometer and was the first RICH counter ever u...

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

Science.gov (United States)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- The U.S. Lab Destiny rests in the payload bay of Space Shuttle Atlantis before closure of the doors. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. Destiny will be attached to the Unity node on the ISS using the Shuttle'''s robot arm, seen here on the left side, with the help of an elbow camera attached to the arm (near the upper end of the lab in the photo). This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

Enhancement of ferromagnetic properties in Zn0.98Cu0.02O by additional Co doping

International Nuclear Information System (INIS)

Liu, Huilian; Zhang, Xu; Liu, Hongbo; Yang, Jinghai; Liu, Yang; Liu, Xiaoyan; Gao, Ming; Wei, Maobin; Cheng, Xin; Wang, Jian

2013-01-01

Highlights: •The samples were synthesized by sol–gel technology to dope up to 3% Co in ZnCuO. •After Co doped into Zn 0.98 Cu 0.02 O sample photoluminescence shows an increase in green emission. •The saturation magnetization increased with Co doping. -- Abstract: Zn 0.98 Cu 0.02 O and Zn 0.95 Cu 0.02 Co 0.03 O powders were synthesized by sol–gel method, and the effects of Co codoping on the structure, optical and magnetic properties of the Zn 0.98 Cu 0.02 O powders were studied in detail. The X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) measurement shows the Zn 0.98 Cu 0.02 O and Zn 0.95 Cu 0.02 Co 0.03 O powders were single phase with the ZnO wurtzite structure, and there was no ferromagnetic-related secondary phase in these powders. Moreover, these powders exhibited ferromagnetism at the room temperature investigated by the magnetic measurement, and the ferromagnetism of the Zn 0.98 Cu 0.02 O and Zn 0.95 Cu 0.02 Co 0.03 O samples were originated from the fact that the Cu ions and Co, Cu ions doped into the ZnO lattices, respectively. In addition, the saturation magnetization (Ms) was significantly increased with Co codoping due to the increased density of oxygen vacancies

15 CFR 930.98 - Federally assisted activities outside of the coastal zone or the described geographic area.

Science.gov (United States)

2010-01-01

... of the coastal zone or the described geographic area. 930.98 Section 930.98 Commerce and Foreign... Federally assisted activities outside of the coastal zone or the described geographic area. State agencies should monitor proposed federal assistance activities outside of the coastal zone or the described...

18F-FET and 18F-FCH uptake in human glioblastoma T98G cell lines

International Nuclear Information System (INIS)

Persico, Marco Giovanni; Buroni, Federica Eleonora; Pasi, Francesca; Lodola, Lorenzo; Aprile, Carlo; Nano, Rosanna; Hodolic, Marina

2016-01-01

Despite complex treatment of surgery, radiotherapy and chemotherapy, high grade gliomas often recur. Differentiation between post-treatment changes and recurrence is difficult. 18 F-methyl-choline ( 18 F-FCH) is frequently used in staging and detection of recurrent prostate cancer disease as well as some brain tumours; however accumulation in inflammatory tissue limits its specificity. The 18 F-ethyl-tyrosine ( 18 F-FET) shows a specific uptake in malignant cells, resulting from increased expression of amino acid transporters or diffusing through the disrupted blood-brain barrier. 18 F-FET exhibits lower uptake in machrophages and other inflammatory cells. Aim of this study was to evaluate 18 F-FCH and 18 F-FET uptake by human glioblastoma T98G cells. Human glioblastoma T98G or human dermal fibroblasts cells, seeded at a density to obtain 2 × 10 5 cells per flask when radioactive tracers were administered, grew adherent to the plastic surface at 37°C in 5% CO 2 in complete medium. Equimolar amounts of radiopharmaceuticals were added to cells for different incubation times (20 to 120 minutes) for 18 F-FCH and 18 F-FET respectively. The cellular radiotracer uptake was determined with a gamma counter. All experiments were carried out in duplicate and repeated three times. The uptake measurements are expressed as the percentage of the administered dose of tracer per 2 × 10 5 cells. Data (expressed as mean values of % uptake of radiopharmaceuticals) were compared using parametric or non-parametric tests as appropriate. Differences were regarded as statistically significant when p<0.05. A significant uptake of 18 F-FCH was seen in T98G cells at 60, 90 and 120 minutes. The percentage uptake of 18 F-FET in comparison to 18 F-FCH was lower by a factor of more than 3, with different kinetic curves. 18 F-FET showed a more rapid initial uptake up to 40 minutes and 18 F-FCH showed a progressive rise reaching a maximum after 90 minutes. 18 F-FCH and 18 F-FET are candidates

Stable Atmospheric Boundary Layer Experiment in Spain (SABLES 98) : a report

NARCIS (Netherlands)

Cuxart, J.; Yague, C.; Morales, G.; Terradelles, E.; Orbe, J.; Calvo, J.; Vilu-Guerau, de J.; Soler, M.R.; Infante, C.; Buenestado, P.; Espinalt, A.; Jorgensem, H.E.

2000-01-01

This paper describes the Stable Atmospheric Boundary Layer Experiment in Spain (SABLES 98), which took place over the northern Spanish plateau comprising relatively flat grassland, in September 1998. The main objectives of the campaign were to study the properties of the mid-latitude stable boundary

Village Power '98

Energy Technology Data Exchange (ETDEWEB)

Cardinal, Julie; Flowers, Larry; Siegel, Judy; Taylor, Roger; Weingart, Jerome

1999-03-24

This is the fifth Village Power workshop sponsored by NREL. We have held these meetings every year since 1993, to focus, challenge, and provide a forum for interaction among practitioners working in the field of using renewable energy technologies as an economically viable pathway to electrification of rural populations throughout the world. Starting with a small group of 30 colleagues in 1993, this ''workshop'' has doubled in size every year. When the NREL staff was planning for this meeting, they were hoping for something around 400 participants. We are now looking at over 500, and we apologize for the somewhat cramped accommodations. This overwhelming response, however, shows that the use of renewable energy to solve some of the world's serious problems is coming of age. This meeting, this ''conference'' (it's clearly no longer a workshop) marks a transition. A transition from the viewpoint that renewables are, and forever will be a technology of the future; to the reality that renewables have come of age. We have technologies available today, at today's prices, that can make a substantive contribution to the pressing needs of environmentally sustainable development in the world. This is a collection of all the papers presented at the Village Power '98 conference.

The BEL information extraction workflow (BELIEF): evaluation in the BioCreative V BEL and IAT track

OpenAIRE

Madan, Sumit; Hodapp, Sven; Senger, Philipp; Ansari, Sam; Szostak, Justyna; Hoeng, Julia; Peitsch, Manuel; Fluck, Juliane

2016-01-01

Network-based approaches have become extremely important in systems biology to achieve a better understanding of biological mechanisms. For network representation, the Biological Expression Language (BEL) is well designed to collate findings from the scientific literature into biological network models. To facilitate encoding and biocuration of such findings in BEL, a BEL Information Extraction Workflow (BELIEF) was developed. BELIEF provides a web-based curation interface, the BELIEF Dashboa...

Technology and job retention among young adults, 1980-98

OpenAIRE

Zavodny, Madeline

2000-01-01

Although many studies have examined whether job stability and security have declined over time, the role of technology in job turnover has received little attention. This analysis examines the relationship between the likelihood that a worker remains at the same job for two years and various measures of technology usage across industries. Using data from the National Longitudinal Survey of Youth over 1980-98, the results indicate that the relationship between job retention and technology vari...

Toroidal deuteron accelerator for Mo-98 neutron activation

Energy Technology Data Exchange (ETDEWEB)

Araujo, Wagner L., E-mail: wagner.leite@ifnmg.edu.br, E-mail: tprcampos@pq.cnpq.br [Instituto Federal do Norte de Minas Gerais (IFN-MG), Montes Claros, MG (Brazil); Campos, Tarcisio P.R. Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear

2017-07-01

The radionuclide Tc-{sup 99m} is the most useful radioisotope in nuclear medicine. It can be produced by the Mo-99 beta minus decay. Mo-99 has often been produced in a high- flux nuclear reactor through radioactive neutron capture reactions on Mo-98. The present paper provides a preliminary design of a toroidal transmutation system (TTS) based on a toroidal compact deuteron accelerator, which can provide the Mo-98 transmutation into Mo-99. This system is essentially composed of a multi-aperture plasma electrode and a target, submitted to 180 kV, where a positive deuteron beam is accelerated toward a titanium-target loaded with deuterium in which nuclear d-d fusion reactions are induced. The Particle Studio package of the Computer Simulation Technology (CST) software was applied to design, simulate and optimize the deuteron beam on the target. MCNP code provided to neutronic analysis. Based on electromagnetic and neutronic simulations, the neutron yield and reaction rates were estimated. The simulated data allowed appraising the Mo-99 activity. A TTS, in a specific configuration, could produce a total deuterium current of 1.6 A at the target and a neutron yield of 10{sup 13} n.s{sup -1}. In a arrangement of 30 column samples, TTS provides 230 mCi s{sup -1} Mo{sup 99} in each column, which represents 80% of Tc-99m in secular equilibrium. As conclusion, the system holds potential for generating Mo-99 and Tc-99m in a suitable activity in secular equilibrium. (author)

Toroidal deuteron accelerator for Mo-98 neutron activation

International Nuclear Information System (INIS)

Araujo, Wagner L.; Campos, Tarcisio P.R. Universidade Federal de Minas Gerais

2017-01-01

The radionuclide Tc- 99m is the most useful radioisotope in nuclear medicine. It can be produced by the Mo-99 beta minus decay. Mo-99 has often been produced in a high- flux nuclear reactor through radioactive neutron capture reactions on Mo-98. The present paper provides a preliminary design of a toroidal transmutation system (TTS) based on a toroidal compact deuteron accelerator, which can provide the Mo-98 transmutation into Mo-99. This system is essentially composed of a multi-aperture plasma electrode and a target, submitted to 180 kV, where a positive deuteron beam is accelerated toward a titanium-target loaded with deuterium in which nuclear d-d fusion reactions are induced. The Particle Studio package of the Computer Simulation Technology (CST) software was applied to design, simulate and optimize the deuteron beam on the target. MCNP code provided to neutronic analysis. Based on electromagnetic and neutronic simulations, the neutron yield and reaction rates were estimated. The simulated data allowed appraising the Mo-99 activity. A TTS, in a specific configuration, could produce a total deuterium current of 1.6 A at the target and a neutron yield of 10 13 n.s -1 . In a arrangement of 30 column samples, TTS provides 230 mCi s -1 Mo 99 in each column, which represents 80% of Tc-99m in secular equilibrium. As conclusion, the system holds potential for generating Mo-99 and Tc-99m in a suitable activity in secular equilibrium. (author)

The Importance of CD56 and CD98 Levels in Patients with Recurrent Implantation Failure

Directory of Open Access Journals (Sweden)

Tevfik Berk Bildaci

2017-05-01

Full Text Available Aim: Despite major advances in assisted reproductive techniques, clinical pregnancy rates remain around 31% with fresh embryo transfer and around 41% with oocyte donations. We also know that the implantation process itself and the window period defined as the %u2018%u2019implantation phase%u2019%u2019 are significantly important for successful in-vitro fertilization (IVF cycles. With this study we have tried to determine any differences in immunohistochemical staining for CD56 and CD98 within the implantation phase endometrium of patients with recurrent implantation failure and of a control group that eventually had a successful IVF cycle. Material and Method: This study was retrospectively performed on a total of 36 patients selected out of a database of 6260 patients who received their IVF cycles from 2004 to 2010. Patients were defined as implantation failure if they did not have a positive result for b-HCG testing following at least 3 IVF cycles with a total of at least 8 embryo transfers. The control group was formed with patients who had success (positive b-HCG testing on their first IVF treatment. Results: Comparison of means for CD 56 staining percentages, CD 98 staining percentages, CD 98 staining power, and CD 98 staining score showed significant difference between the control group and the study group (p

A 98 W 1178 nm Yb-doped solid-core photonic bandgap fiber oscillator

International Nuclear Information System (INIS)

Fan, Xinyan; Chen, Mingchen; Shirakawa, Akira; Ueda, Ken-ichi; Olausson, Christina B; Broeng, Jes

2013-01-01

A high-power ytterbium-doped solid-core photonic bandgap fiber laser directly oscillating at 1178 nm is reported. The sharp-cut bandpass distributed filtering effect of photonic bandgap fiber can suppress amplified spontaneous emission (ASE) in the conventional high-gain spectral region. The oscillator is composed of a high reflection fiber Bragg grating spliced with a 39 m gain fiber and a Fresnel fiber end surface. A model based on rate equations is investigated numerically. A record output power of 98 W is achieved with a slope efficiency of 54%. The laser linewidth is 0.5 nm. The spectrum at 98 W indicates that ASE and parasitic lasing are suppressed effectively. (letter)

Estradiol Receptors Regulate Differential Connexin 43 Expression in F98 and C6 Glioma Cell Lines.

Directory of Open Access Journals (Sweden)

Zahra Moinfar

Full Text Available Glioma is the most common malignant primary brain tumour with male preponderance and poor prognosis. Glioma cells express variable amounts of connexin 43 (Cx43 and estrogen receptors (ERs. Both, Cx43 and ERs, play important roles in cell proliferation and migration. Therefore, we investigated the effects of 17-ß estradiol (E2 on Cx43 expression in two glioma cell lines with variable native expression of Cx43.F98 and C6 rat glioma cells were cultured for 24 h in the presence of 10 nM or 100 nM E2, and the E2-antagonist, Fulvestrant. An MTT assay was performed to evaluate cell viability. ERα, ERβ and Cx43 protein expressions were analysed by western blotting and Cx43 mRNA expression was analysed by real-time polymerase chain reaction. To quantify cell migration, an exclusive zone migration assay was used. Functional coupling of cells via gap junctions was examined using whole-cell patch-clamp technique.E2 reduced Cx43 expression in C6 cells, but increased Cx43 expression in F98 cultures. These effects were mediated via ERs. Moreover, E2 promoted C6 cell migration, but it did not affect F98 cell migration. The expression level of ERα was found to be high in C6, but low in F98 cells. ERβ was exclusively expressed in C6 cells. In addition, E2 treatment induced a significant decrease of ERβ in C6 cultures, while it decreased ERα expression in F98 glioma cells.These findings show that E2 differentially modulates Cx43 expression in F98 and C6 glioma cells, likely due to the differential expression of ERs in each of these cell lines. Our findings point to the molecular mechanisms that might contribute to the gender-specific differences in the malignancy of glioma and could have implications for therapeutic strategies against glioma.

29 CFR 98.325 - What happens if I do business with an excluded person in a covered transaction?

Science.gov (United States)

2010-07-01

... transaction? If as a participant you knowingly do business with an excluded person, we may disallow costs... covered transaction? 98.325 Section 98.325 Labor Office of the Secretary of Labor GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Responsibilities of Participants Regarding Transactions Doing Business...

Propriedades tensiométricas do peritônio da paca (Cuniculus paca a fresco e conservado em glicerina 98%

Directory of Open Access Journals (Sweden)

Angela Daniele de Camargo

2014-02-01

Full Text Available Na busca constante, tanto de material biológico alternativo para a realização de implantes, quanto de novas opções de modelos de experimentação animal, o objetivo desta investigação foi descrever o comportamento mecânico do peritônio da paca (Cuniculus paca Linnaeus, 1766 a fresco e conservado em glicerina a 98%. Amostras frescas e conservadas em glicerina por períodos de 30, 60 e 90 dias foram submetidas a testes mecânicos de tração. Quatro animais adultos, três machos e uma fêmeas, com peso corporal médio de oito quilogramas, foram utilizados para colheita das amostras de peritônio. Todos os tecidos conservados em glicerina a 98% apresentaram diminuição na rigidez e aumento na ductibilidade e tenacidade. Considerando-se a força máxima aplicada ao peritônio, evidenciou-se aumento significativo nos valores (p<0,01 das amostras conservadas por 60 e 90 dias, quando comparado ao material a fresco. Com relação a variável alongamento, notou-se aumento nos valores relativos aos materiais em glicerina em todos os tempos de conservação, verificando-se diferença significativa (p<0,01 entre os valores das amostras a fresco. A variável área também se apresentou significativa (p<0,01 entre os valores das amostras a fresco (5,40 mm² e os preservados em glicerina pelos períodos de 30 dias (4,50 mm², 60 dias (9,00 mm² e 90 dias (7,20 mm², indicando assim, que a área desta membrana aumentou em 0,033 mm² por dia. Mediante os resultados observados, concluiu-se que a glicerina 98% é uma substância eficiente para a conservação do peritônio da paca, pois melhorou suas propriedades mecânicas permitindo que as membranas suportem maiores forças de deformação. Assim, os resultados obtidos nos ensaios mecânicos do peritônio da paca sugerem sua utilização como mais uma opção de material biológico.

78 FR 39437 - Proposed Collection; Comment Request for Revenue Procedure 98-32

Science.gov (United States)

2013-07-01

... Revenue Procedure 98-32, Electronic Federal Tax Payment System (EFTPS) Programs for Reporting Agents.... ADDRESSES: Direct all written comments to Yvette Lawrence, Internal Revenue Service, Room 6129, 1111... Internet at [email protected] . SUPPLEMENTARY INFORMATION: Title: Electronic Federal Tax Payment...

Micromagnetic Code Development of Advanced Magnetic Structures Final Report CRADA No. TC-1561-98

Energy Technology Data Exchange (ETDEWEB)

Cerjan, Charles J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Shi, Xizeng [Read-Rite Corporation, Fremont, CA (United States)

2017-11-09

The specific goals of this project were to: Further develop the previously written micromagnetic code DADIMAG (DOE code release number 980017); Validate the code. The resulting code was expected to be more realistic and useful for simulations of magnetic structures of specific interest to Read-Rite programs. We also planned to further the code for use in internal LLNL programs. This project complemented LLNL CRADA TC-840-94 between LLNL and Read-Rite, which allowed for simulations of the advanced magnetic head development completed under the CRADA. TC-1561-98 was effective concurrently with LLNL non-exclusive copyright license (TL-1552-98) to Read-Rite for DADIMAG Version 2 executable code.

200 Area effluent treatment facility process control plan 98-02

International Nuclear Information System (INIS)

Le, E.Q.

1998-01-01

This Process Control Plan (PCP) provides a description of the background information, key objectives, and operating criteria defining Effluent Treatment Facility (ETF) Campaign 98-02 as required per HNF-IP-0931 Section 37, Process Control Plans. Campaign 98-62 is expected to process approximately 18 millions gallons of groundwater with an assumption that the UP-1 groundwater pump will be shut down on June 30, 1998. This campaign will resume the UP-1 groundwater treatment operation from Campaign 97-01. The Campaign 97-01 was suspended in November 1997 to allow RCRA waste in LERF Basin 42 to be treated to meet the Land Disposal Restriction Clean Out requirements. The decision to utilize ETF as part of the selected interim remedial action of the 200-UP-1 Operable Unit is documented by the Declaration of the Record of Decision, (Ecology, EPA and DOE 1997). The treatment method was chosen in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA), the Hanford Federal Facility Agreement and Consent Order (known as the Tri-Party Agreement or TPA), and to the extent practicable, the National Oil and Hazardous Substances Pollution Contingency Plan (NCP)

Grain refinement of Al-Si9.8-Cu3.4 alloy by novel Al-3.5FeNb-1.5C master alloy and its effect on mechanical properties

Science.gov (United States)

Apparao, K. Ch; Birru, Anil Kumar

2018-01-01

A novel Al-3.5FeNb-1.5C master alloy with uniform microstructure was prepared using a melt reaction process for this study. In the master alloy, basic intermetallic particles such as NbAl3, NbC act as heterogeneous nucleation substrates during the solidification of aluminium. The grain refining performance of the novel master alloy on Al-Si9.8-Cu3.4 alloy has also been investigated. It is observed that the addition of 0.1 wt.% of Al-3.5FeNb-1.5C master alloy can induce very effective grain refinement of the Al-Si9.8-Cu3.4 alloy. The average grain size of α-Al is reduced to 22.90 μm from about 61.22 μm and most importantly, the inoculation of Al-Si9.8-Cu3.4 alloy with FeNb-C is not characterised by any visible poisoning effect, which is the drawback of using commercial Al-Ti-B master alloys on aluminium cast alloys. Therefore, the mechanical properties of the Al-Si9.8-Cu3.4 alloy have been improved obviously by the addition of the 0.1 wt.% of Al-3.5FeNb-1.5C master alloy, including the yield strength and elongation.

Dipole strength distribution below the giant dipole resonance in {sup 92}Mo, {sup 98}Mo and {sup 100}Mo

Energy Technology Data Exchange (ETDEWEB)

Rusev, G.Y.

2006-07-01

Investigations of the dipole-strength distributions in {sup 92}Mo, {sup 98}Mo and {sup 100}Mo were carried out by means of the method of nuclear resonance fluorescence. The low-lying excitations in the nuclides {sup 92}Mo, {sup 98}Mo and {sup 100}Mo have been studied in photon-scattering experiments at an electron energy of 6 MeV at the ELBE accelerator and at electron energies from 3.2 to 3.8 MeV at the Dynamitron accelerator. Five levels were observed in {sup 92}Mo. Five levels in {sup 98}Mo and 14 in {sup 100}Mo were identified for the first time in the energy range from 2 to 4 MeV. Dipole-strength distributions up to the neutron-separation energies in the nuclides {sup 92}Mo, {sup 98}Mo and {sup 100}Mo have been investigated at the ELBE accelerator. Because of the possible observation of transitions in the neighboring nuclei produced via ({gamma},n) reaction, additional measurements at electron energies of 8.4 and 7.8 MeV, below the neutron-separation energy, were performed on {sup 98}Mo and {sup 100}Mo, respectively. The number of transitions assigned to {sup 92}Mo, {sup 98}Mo and {sup 100}Mo is 340, 485 and 499, respectively, the main part of them being dipole transitions. Statistical properties of the observed transitions are obtained. The continuum contains the ground-state transitions as well as the branching transitions to the low-lying levels and the subsequent deexcitations of these levels. (orig.)

Deep and shallow acceptor levels in solid solutions Pb0.98Sm0.02S

International Nuclear Information System (INIS)

Hasanov, H.A.; Rahimov, R.Sh.

2010-01-01

It is well known that the metal vacancies the energy levels of which take place between permitted energies of valency band, are the main acceptor centers in the led salts and solid solutions on their base. The aim of the given paper is founding of character of acceptor levels in single crystals Pb 0 .98Sm 0 .02S with low concentrations of charge carrier. The deep and shallow acceptor levels are found at investigation of Hall effect in Pb 0 .98Sm 0 .02S solid solution with character of low concentrations of charge carriers in crystals

Mass Spectrometry of Intact Proteins Reveals +98 u Chemical Artifacts Following Precipitation in Acetone.

Science.gov (United States)

Güray, Melda Z; Zheng, Shi; Doucette, Alan A

2017-02-03

Protein precipitation in acetone is frequently employed ahead of mass spectrometry for sample preconcentration and purification. Unfortunately, acetone is not chemically inert; mass artifacts have previously been observed on glycine-containing peptides when exposed to acetone under acidic conditions. We herein report a distinct chemical modification occurring at the level of intact proteins when incubated in acetone. This artifact manifests as one or more satellite peaks in the MS spectrum of intact protein, spaced 98 u above the mass of the unmodified protein. Other artifacts (+84, +112 u) also appear upon incubation of proteins or peptides in acetone. The reaction is pH-sensitive, being suppressed when proteins are exposed to acetone under acidic conditions. The +98 u artifact is speculated to originate through an intermediate product of aldol condensation of acetone to form diacetone alcohol and mesityl oxide. A +98 u product could originate from nucleophilic attack on mesityl oxide or through condensation with diacetone alcohol. Given the extent of modification possible upon exposure of proteins to acetone, particularly following overnight solvent exposure or incubation at room temperature, an awareness of the variables influencing this novel modification is valued by proteomics researchers who employ acetone precipitation for protein purification.

Final Technical Report for DE-FG02-98ER45737

Energy Technology Data Exchange (ETDEWEB)

Ade, Harald W.

2018-04-24

Final Technical Report For DOE Grant No. DE-FG02-98ER45737 Development of a Scanning Transmission X-Ray Microscope Polymer Thin Films and Self Assembled Monolayers: Pattern Formation and Surface Interactions NEXAFS Microscopy and Resonant Scattering of Polymeric Materials Organic Heterojunction Devices: Structure, Composition, and Performance at <20 nm Resolution Fundamental Science of High Open Circuit Voltage Excitonic Solar Cells Control of Interface- and Mesoscopic Structure in High Performance Organic Solar Cells: Towards a Predictive Device Paradigm

Fusion of NUP98 and the SET binding protein 1 (SETBP1) gene in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12)

DEFF Research Database (Denmark)

Panagopoulos, Ioannis; Kerndrup, Gitte; Carlsen, Niels

2007-01-01

Three NUP98 chimaeras have previously been reported in T cell acute lymphoblastic leukaemia (T-ALL): NUP98/ADD3, NUP98/CCDC28A, and NUP98/RAP1GDS1. We report a T-ALL with t(11;18)(p15;q12) resulting in a novel NUP98 fusion. Fluorescent in situ hybridisation showed NUP98 and SET binding protein 1(...... in leukaemias; however, it encodes a protein that specifically interacts with SET, fused to NUP214 in a case of acute undifferentiated leukaemia.......Three NUP98 chimaeras have previously been reported in T cell acute lymphoblastic leukaemia (T-ALL): NUP98/ADD3, NUP98/CCDC28A, and NUP98/RAP1GDS1. We report a T-ALL with t(11;18)(p15;q12) resulting in a novel NUP98 fusion. Fluorescent in situ hybridisation showed NUP98 and SET binding protein 1...

Delirium subtype identification and the validation of the Delirium Rating Scale--Revised-98 (Dutch version) in hospitalized elderly patients

NARCIS (Netherlands)

de Rooij, Sophia E.; van Munster, Barbara C.; Korevaar, Johanna C.; Casteelen, Gerty; Schuurmans, Marieke J.; van der Mast, Roos C.; Levi, Marcel

2006-01-01

BACKGROUND: Delirium is the most common acute neuropsychiatric disorder in hospitalized elderly. The Dutch version of the Delirium Rating Scale-Revised-98 (DRS-R-98) appears to be a reliable method to classify delirium. The aim of this study was to determine the validity and reliability of the

45 CFR 98.51 - Activities to improve the quality of child care.

Science.gov (United States)

2010-10-01

... health and safety, nutrition, first aid, the recognition of communicable diseases, child abuse detection... 45 Public Welfare 1 2010-10-01 2010-10-01 false Activities to improve the quality of child care... CHILD CARE AND DEVELOPMENT FUND Use of Child Care and Development Funds § 98.51 Activities to improve...

Features of the structural and magnetic properties of Pb(TixZr1–xO3-NiFe1.98Co0.02O4 in the polarized state

Directory of Open Access Journals (Sweden)

Baev Vadim

2017-06-01

Full Text Available Composites with a 90%Pb(TixZr1-xO3-10%NiFe1.98Co0.02O4 composition have been synthesized. It has been established that the polarization of samples resulting from exposure to an electric field for 1 hour of 4 kV/mm in strength at a temperature of 400 K leads to crystal structure deformation. The compression of elementary crystal cells in some areas during polarization of the sample creates conditions suitable for the enhancement of magnetic exchange interactions. It has been found that the polarization process of such compositions leads to increases in specific magnetization and magnetic susceptibility. The analysis of Mössbauer spectra has shown that the polarization of the 90%Pb(TixZr1-xO3-10%NiFe1.98Co0.02O4 composite leads to significant changes in the effective magnetic fields of iron subspectra in various positions.

Laboratory directed research and development FY98 annual report; TOPICAL

International Nuclear Information System (INIS)

Al-Ayat, R; Holzrichter, J

1999-01-01

In 1984, Congress and the Department of Energy (DOE) established the Laboratory Directed Research and Development (LDRD) Program to enable the director of a national laboratory to foster and expedite innovative research and development (R and D) in mission areas. The Lawrence Livermore National Laboratory (LLNL) continually examines these mission areas through strategic planning and shapes the LDRD Program to meet its long-term vision. The goal of the LDRD Program is to spur development of new scientific and technical capabilities that enable LLNL to respond to the challenges within its evolving mission areas. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies and enables the Laboratory to attract the most qualified scientists and engineers. The FY98 LDRD portfolio described in this annual report has been carefully structured to continue the tradition of vigorously supporting DOE and LLNL strategic vision and evolving mission areas. The projects selected for LDRD funding undergo stringent review and selection processes, which emphasize strategic relevance and require technical peer reviews of proposals by external and internal experts. These FY98 projects emphasize the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs

Fretting-corrosion at the modular tapers interface: Inspection of standard ASTM F1875-98.

Science.gov (United States)

Bingley, Rachel; Martin, Alan; Manfredi, Olivia; Nejadhamzeeigilani, Mahdiyar; Oladokun, Abimbola; Beadling, Andrew Robert; Siddiqui, Sohail; Anderson, James; Thompson, Jonathan; Neville, Anne; Bryant, Michael

2018-05-01

Interest in the degradation mechanisms at the modular tapers interfaces has been renewed due to increased reported cases of adverse reactions to metal debris and the appearance of wear and corrosion at the modular tapers interfaces at revision. Over the past two decades, a lot of research has been expended to understand the degradation mechanisms, with two primary implant loading procedures and orientations used consistently across the literature. ASTM F1875-98 is often used as a guide to understand and benchmark the tribocorrosion processes occurring within the modular tapers interface. This article presents a comparison of the two methods outlined in ASTM F1875-98 as well as a critique of the standard considering the current paradigm in pre-clinical assessment of modular tapers.

Novel compound heterozygous mutations in the GPR98 (USH2C) gene identified by whole exome sequencing in a Moroccan deaf family.

Science.gov (United States)

Bousfiha, Amale; Bakhchane, Amina; Charoute, Hicham; Detsouli, Mustapha; Rouba, Hassan; Charif, Majida; Lenaers, Guy; Barakat, Abdelhamid

2017-10-01

In the present work, we identified two novel compound heterozygote mutations in the GPR98 (G protein-coupled receptor 98) gene causing Usher syndrome. Whole-exome sequencing was performed to study the genetic causes of Usher syndrome in a Moroccan family with three affected siblings. We identify two novel compound heterozygote mutations (c.1054C > A, c.16544delT) in the GPR98 gene in the three affected siblings carrying post-linguale bilateral moderate hearing loss with normal vestibular functions and before installing visual disturbances. This is the first time that mutations in the GPR98 gene are described in the Moroccan deaf patients.

Indoor and outdoor genotoxic load detected by the Comet assay in leaves of Nicotiana tabacum cultivars Bel B and Bel W3.

Science.gov (United States)

Restivo, Francesco Maria; Laccone, Maria Concetta; Buschini, Annamaria; Rossi, Carlo; Poli, Paola

2002-03-01

Environmental pollution assessment and control are priority issues for both developed and developing countries of the world. The use of plant material for a more complete picture of environmental health appears to be particularly appealing. Here we validate a previous plant-adapted Comet assay on leaf tissues of Nicotiana tabacum cultivars Bel B and Bel W3. The effects of H(2)O(2) on DNA damage in Bel B and Bel W3 agree with the hypothesis that some component of the machinery that protects DNA integrity from oxidative stress may be impaired in cv. Bel W3. Exposure in the field on sunny summer days (peak ozone concentration >80 p.p.b.) showed significantly higher DNA damage in cv. Bel W3 if plants were collected and subjected to the Comet assay when the air ozone concentration was reaching its peak value, but not when plants were sampled early in the morning and hence after a period of low ozone concentration. The different results suggest that Bel W3 possesses a less efficient recovery apparatus that requires a longer period of activity to be effective and/or is less protected against reactive oxygen species production during exposure to ozone. However, it cannot be excluded that the increase in mean DNA damage is the result of the presence of a genotoxic agent(s) other than ozone. Interestingly, Bel W3 also appears to be more responsive, compared with Bel B, when exposed to ambient indoor pollutants. The use of cv. Bel W3 increases the sensitivity of the assay under both indoor and field conditions. However, different classes of mutagens should be tested to define the range of profitable utilization of this tobacco cultivar for environmental genotoxicity detection.

Sexuelle Belästigung aus strafrechtlicher Sicht

Directory of Open Access Journals (Sweden)

Maria Eder-Rieder

2004-07-01

Full Text Available Der Kern der Arbeit ist die juristische Aufarbeitung der Grenzen und Reichweite der in der Schweiz seit 1. Oktober 1992 in Kraft befindlichen Regelungen zur sexuellen Belästigung durch Vornahme einer sexuellen Handlung vor jemanden (Art. 198 Abs. 1 StGB, der tätlichen sexuellen Belästigung und der verbalen Belästigung (Art. 198 Abs. 2 StGB. Diese Tatbestände werden anhand von Beispielen erläutert, mit weiteren Varianten der sexuellen Belästigung verglichen und zu anderen Tatbeständen abgegrenzt. Ebenso wird auf das Verhältnis zum Zivilrecht und die Problematik des Strafprozesses eingegangen. Abschließend wird der kriminalpolitischen Frage über den Sinn der strafrechtlichen Sanktionierung nachgegangen.

Problems of Chernobyl. Materials of International scientific and practical conference 'Shelter-98'

International Nuclear Information System (INIS)

Klyuchnikov, O.O.

1999-01-01

These transactions contain materials of International Scientific and Practical Conference 'Shelter-98', which was held 27-30 November 1998 in Slavutich. They describe the results of the research work of the specialists from Ukraine, neighborhood and far foreign counties. The results, targeted at solving the problems of converting the Shelter Object into oncologically safe state

Identification and Quantification of Alkaloid in KHR98 and Fragmentation Pathways in HPLC-Q-TOF-MS.

Science.gov (United States)

Long, Jiakun; Wang, Yang; Xu, Chen; Liu, Tingting; Duan, Gengli; Yu, Yingjia

2018-05-01

Uncaria rhynchophylla is woody climber plant distributed mainly in China and Japan, the stems and hooks of which can be collected as "Gou-Teng" for the treatment of hyperpyrexia, epilepsy and preeclampsia. Fudan University first manufactured KHR98, the extract of Uncaria rhynchophylla. In order to study the active components and structural information of KHR98, we established a HPLC coupled with quadrupole time-of-flight (Q-TOF)-MS method for rapid analysis of alkaloids. In qualitative analysis, a total of eight compounds, including four known alkaloids and four unknown components, were detected and identified. The fragmentation behaviors, such as the fragment ion information and the fragmentation pathways of the eight components were summarized simultaneously, and the concentration of the above components was determined by HPLC-MS method. The quantitative method was proved to be reproducible, precise and accurate. This study shed light on the standardization and quality control of the KHR98 and provided a foundation for the further research on pharmacology, follow-up clinical research and New Drug Applications.

Revisiting anomalous B(E2;41+→21+)/B(E2;21+→01+) values in 98Ru and 180Pt

International Nuclear Information System (INIS)

Williams, E.; Plettner, C.; McCutchan, E. A.; Levine, H.; Casten, R. F.; Ai, H.; Heinz, A.; Qian, J.; Meyer, D. A.; Werner, V.; Zamfir, N. V.; Cakirli, R. B.; Beausang, C. W.; Guerdal, G.; Pietralla, N.

2006-01-01

Recently, a set of nine nonmagic nuclei with anomalous values of the B(E2) ratio B 4/2 ≡B(E2;4 1 + →2 1 + )/B(E2;2 1 + →0 1 + ) 1 + →2 1 + ) values for two of these nuclei, 98 Ru and 180 Pt, were re-measured to determine if the current literature values for these nuclei are correct. 98 Ru was studied in a 27 Al( 98 Ru, 98 Ru*) Coulomb excitation experiment in inverse kinematics, while the lifetime of the 4 1 + state in 180 Pt was measured in a 122 Sn( 62 Ni, 4n) 180 Pt recoil distance method (RDM) experiment. For both nuclei, the remeasured B 4/2 values are well above 1, removing the deviations from collective models

40 CFR 86.529-98 - Road load force and inertia weight determination.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Road load force and inertia weight... inertia weight determination. (a)(1) Road load as a function of speed is given by the following equation: F = A + CV2 (2) The values for coefficients A and C and the test inertia are given in Figure F98-9...

Survival with 98% methemoglobin levels in a school-aged child during the "festival of colors".

Science.gov (United States)

Sankar, Jhuma; Devangare, Shashikant; Dubey, N K

2013-10-01

Methemoglobin levels more than 70% have almost always been reported to have been fatal. The case of a 4-year-old boy who survived with methemoglobin levels of 98% is presented here. He was brought to the emergency department with complaints of vomiting, pain abdomen, and altered sensorium following accidental ingestion of paint thinner mixed with "Holi" colors. On examination, the child was in altered sensorium, cyanosed with saturations of 55%, who did not respond despite positive pressure ventilation with 100% oxygen. A possibility of toxic methemoglobinemia was considered and confirmed by finding of elevated methemoglobin levels of 98%. The child survived with definitive therapy with methylene blue and aggressive goal-directed approach.

Variations in teenage birth rates, 1991-98: national and state trends.

Science.gov (United States)

Ventura, S J; Curtin, S C; Mathews, T J

2000-04-24

This report presents national birth rates for teenagers for 1991-98 and the percent change, 1991-98. State-specific teenage birth rates by age, race, and Hispanic origin for 1991 and 1998 and the percent change, 1991 to 1998, are also presented. Tabular and graphical descriptions of the trends in teenage birth rates for the Nation and each State, by age group, race, and Hispanic origin of the mother, are discussed. Birth rates for teenagers 15-19 years declined nationally between 1991 and 1998 for all age and race and Hispanic origin populations, with the steepest declines recorded for black teenagers. State-specific rates fell significantly in all States for ages 15-19 years; declines ranged from 10 to 38 percent. In general, rates by State fell more for younger than for older teenagers, ranging by State from 10 to 46 percent for ages 15-17 years. Statistically significant reductions for older teenagers ranged from 3 to 39 percent. Reductions by State were largest for black teenagers 15-19 years, with rates falling 30 percent or more in 15 States. Among the factors accounting for these declines are decreased sexual activity, increases in condom use, and the adoption of the implant and injectable contraceptives.

Propriedades tensiométricas do peritônio da paca (Cuniculus paca) a fresco e conservado em glicerina 98%

OpenAIRE

Angela Daniele de Camargo; Paulo César de Camargo; Leonardo Martins Leal; Sérgio Pinter Garcia Filho; Leandro Luís Martins; Antônio Carlos Shimano; Márcia Rita Fernandes Machado

2014-01-01

Na busca constante, tanto de material biológico alternativo para a realização de implantes, quanto de novas opções de modelos de experimentação animal, o objetivo desta investigação foi descrever o comportamento mecânico do peritônio da paca (Cuniculus paca Linnaeus, 1766) a fresco e conservado em glicerina a 98%. Amostras frescas e conservadas em glicerina por períodos de 30, 60 e 90 dias foram submetidas a testes mecânicos de tração. Quatro animais adultos, três machos e uma fêmeas, com pes...

The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation

Czech Academy of Sciences Publication Activity Database

Cho, J. Y.; Fox, D. A.; Hořejší, Václav; Sagawa, K.; Skubitz, K. M.; Katz, D. R.; Chain, B.

2001-01-01

Roč. 98, č. 2 (2001), s. 374-382 ISSN 0006-4971 R&D Projects: GA ČR GA310/99/0349 Institutional research plan: CEZ:AV0Z5052915 Keywords : integrin * CD98 * CD147 Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 9.273, year: 2001

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

Energy Technology Data Exchange (ETDEWEB)

Di Nunzio, Francesca, E-mail: francesca.di-nunzio@pasteur.fr [Molecular Virology and Vaccinology unit, CNRS URA 3015, Department of Virology, Institut Pasteur, 25-28 rue du Dr. Roux, 75015 Paris (France); Fricke, Thomas [Department of Microbiology and Immunology, Albert Einstein College of Medicine Bronx, NY 10461 (United States); Miccio, Annarita [University of Modena e Reggio Emilia, Centro di Medicina Rigenerativa, Modena (Italy); Valle-Casuso, Jose Carlos; Perez, Patricio [Department of Microbiology and Immunology, Albert Einstein College of Medicine Bronx, NY 10461 (United States); Souque, Philippe [Molecular Virology and Vaccinology unit, CNRS URA 3015, Department of Virology, Institut Pasteur, 25-28 rue du Dr. Roux, 75015 Paris (France); Rizzi, Ermanno; Severgnini, Marco [Institute of Biomedical Technologies, CNR, Milano (Italy); Mavilio, Fulvio [University of Modena e Reggio Emilia, Centro di Medicina Rigenerativa, Modena (Italy); Genethon, Evry (France); Charneau, Pierre [Molecular Virology and Vaccinology unit, CNRS URA 3015, Department of Virology, Institut Pasteur, 25-28 rue du Dr. Roux, 75015 Paris (France); Diaz-Griffero, Felipe, E-mail: felipe.diaz-griffero@einstein.yu.edu [Department of Microbiology and Immunology, Albert Einstein College of Medicine Bronx, NY 10461 (United States)

2013-05-25

The early steps of HIV-1 replication involve the entry of HIV-1 into the nucleus, which is characterized by viral interactions with nuclear pore components. HIV-1 developed an evolutionary strategy to usurp the nuclear pore machinery and chromatin in order to integrate and efficiently express viral genes. In the current work, we studied the role of nucleoporins 153 and 98 (Nup153 and Nup98) in infection of human Jurkat lymphocytes by HIV-1. We showed that Nup153-depleted cells exhibited a defect in nuclear import, while depletion of Nup 98 caused a slight defect in HIV integration. To explore the biochemical viral determinants for the requirement of Nup153 and Nup98 during HIV-1 infection, we tested the ability of these nucleoporins to interact with HIV-1 cores. Our findings showed that both nucleoporins bind HIV-1 cores suggesting that this interaction is important for HIV-1 nuclear import and/or integration. Distribution analysis of integration sites in Nup153-depleted cells revealed a reduced tendency of HIV-1 to integrate in intragenic sites, which in part could account for the large infectivity defect observed in Nup153-depleted cells. Our work strongly supports a role for Nup153 in HIV-1 nuclear import and integration. - Highlights: ► We studied the role of Nup98 and Nup153 in HIV-1 infection. ► Nup98 binds the HIV-1 core and is involved in HIV-1 integration. ► Nup153 binds the HIV-1 core and is involved in HIV-1 nuclear import. ► Depletion of Nup153 decreased the integration of HIV-1 in transcriptionally active sites.

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

International Nuclear Information System (INIS)

Di Nunzio, Francesca; Fricke, Thomas; Miccio, Annarita; Valle-Casuso, Jose Carlos; Perez, Patricio; Souque, Philippe; Rizzi, Ermanno; Severgnini, Marco; Mavilio, Fulvio; Charneau, Pierre; Diaz-Griffero, Felipe

2013-01-01

The early steps of HIV-1 replication involve the entry of HIV-1 into the nucleus, which is characterized by viral interactions with nuclear pore components. HIV-1 developed an evolutionary strategy to usurp the nuclear pore machinery and chromatin in order to integrate and efficiently express viral genes. In the current work, we studied the role of nucleoporins 153 and 98 (Nup153 and Nup98) in infection of human Jurkat lymphocytes by HIV-1. We showed that Nup153-depleted cells exhibited a defect in nuclear import, while depletion of Nup 98 caused a slight defect in HIV integration. To explore the biochemical viral determinants for the requirement of Nup153 and Nup98 during HIV-1 infection, we tested the ability of these nucleoporins to interact with HIV-1 cores. Our findings showed that both nucleoporins bind HIV-1 cores suggesting that this interaction is important for HIV-1 nuclear import and/or integration. Distribution analysis of integration sites in Nup153-depleted cells revealed a reduced tendency of HIV-1 to integrate in intragenic sites, which in part could account for the large infectivity defect observed in Nup153-depleted cells. Our work strongly supports a role for Nup153 in HIV-1 nuclear import and integration. - Highlights: ► We studied the role of Nup98 and Nup153 in HIV-1 infection. ► Nup98 binds the HIV-1 core and is involved in HIV-1 integration. ► Nup153 binds the HIV-1 core and is involved in HIV-1 nuclear import. ► Depletion of Nup153 decreased the integration of HIV-1 in transcriptionally active sites

Tanks focus area multiyear program plan - FY96-FY98

International Nuclear Information System (INIS)

1995-07-01

The Tanks Focus Area (TFA) Multiyear Program Plan (MYPP) presents the recommended TFA technical program. The recommendation covers a 3-year funding outlook (FY96-FY98), with an emphasis on FY96 and FY97. In addition to defining the recommended program, this document also describes the processes used to develop the program, the implementation strategy for the program, the references used to write this report, data on the U.S. Department of Energy (DOE) tank site baselines, details on baseline assumptions and the technical elements, and a glossary

Spectroscopy of {sup 96}Ru and {sup 98}Ru: structures of varied character at N {>=} 52

Energy Technology Data Exchange (ETDEWEB)

Reviol, W; Garg, U; Aprahamian, A; Davis, B F; Herr, M C; Naguleswaran, S; Walpe, J C; Ye, D [Notre Dame Univ., IN (United States); Ahmad, I; Carpenter, M P; Janssens, R V.F.; Khoo, T L; Lauritsen, T; Liang, Y [Argonne National Lab., IL (United States)

1992-08-01

The authors have investigated the onset of deformation at N {>=} 52 by performing high-spin gamma spectroscopy of {sup 96-98}Ru using the {sup 65}Cu({sup 36}S,pxn) reaction with the Argonne-Notre Dame {gamma}-ray facility. From the coincidence data associated with high multiplicity (k {>=} 8) events, they have established two main band structures in {sup 96-98}Ru which extend the previously-known level schemes significantly (up to > 20 {Dirac_h}). In {sup 96}Ru, one of the newly observed structures consists of five rotation-like E2 transitions and feeds into the known 9{sup (-)} state; the other structure bypasses the first one, and based on the observed level-spacings, is tentatively described as vibration-like. A rotational-like structure above a spin of 8 {Dirac_h}, along with a parallel vibration-like structure, has been observed in {sup 98}Ru as well. The data also contain some evidence for a weak sequence of dipole (presumably M1) transitions in {sup 96}Ru. This structure might be similar to the high-K oblate bands recently observed in {sup 119-123}I and {sup 198-20P}b. 9 refs., 3 figs.

Pino ósseo homólogo conservado em glicerina a 98% e hemicerclagem com fio poliglactina 910 na osteossíntese umeral de pombos domésticos Homologous bone pin conserved in glycerin at 98% and hemicerclagem with a thread of poliglactina 910 in humerus osteosyntesis of domestic pigeons

Directory of Open Access Journals (Sweden)

Juliano Bolson

2008-10-01

Full Text Available O objetivo do presente estudo foi avaliar a utilização de um pino intramedular ósseo homólogo, conservado em glicerina a 98%, associado à hemicerclagem com fio poliglactina 910 na osteossíntese umeral transversa de pombos domésticos (Columba livia. Utilizou-se como pino ósseo a parte distal do tibiotarso, conservado com medula óssea. Foram operados 20 pombos domésticos, adultos, não-sexados e clinicamente sadios. Esses animais foram separados ao acaso em cinco grupos, com quatro indivíduos. O úmero foi seccionado cirurgicamente na sua diáfise, de forma transversa, e o pino ósseo foi devidamente implantado no seio do osso. Orifícios foram realizados e por eles procedeu-se hemicerclagem do tipo pontos de Wolff com poliglactina 910. Os animais foram avaliados clinicamente, por meio de radiografias semanais, e histologicamente após os períodos de 15, 30, 60, 90 e 120 dias. A conservação do pino ósseo em glicerina a 98% foi avaliada por meio de exames microbiológicos. Em todos os animais, pode-se notar, clinicamente, excelente adaptação à cirurgia e normalidade do uso do membro já radiologicamente pode-se observar formação de calo ósseo e cicatrização da fratura. Histologicamente pode-se observar que ocorreu formação de calo ósseo 15 dias após a cirurgia e cicatrização com remodelação completa a partir dos 90 dias. Nesse exame, além de leve a moderada reação inflamatória no período inicial de avaliação, nenhum outro evento foi notado nos períodos subseqüentes. Concluiu-se que a técnica e os materiais utilizados se tornam uma opção altamente viável na osteossíntese umeral transversa de pombos domésticos.The objective of the present study was to evaluate the use of a homologous bone intramedullary pin, conserved in glycerin at 98% associated to hemicerclage with a thread of polyglactina 910 in the transverse humerus osteosynthesis of domestic pigeon (Columba livia. The distal part of the

7 CFR 1755.98 - List of telecommunications specifications included in other 7 CFR parts.

Science.gov (United States)

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false List of telecommunications specifications included in... (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE TELECOMMUNICATIONS POLICIES ON SPECIFICATIONS, ACCEPTABLE MATERIALS, AND STANDARD CONTRACT FORMS § 1755.98 List of telecommunications specifications...

THE 1997-98 FINANCIAL CRISIS IN MALAYSIA: CAUSES, RESPONSE, AND RESULTS

OpenAIRE

HASAN, ZUBAIR

2002-01-01

This paper argues that the 1997-98 financial crisis did not hit Malaysia because the economic fundamentals of the country were weak. It was the result of massive unpredictable flight of short-term portfolio investment from the region including Malaysia. The paper assembles evidence, and employs econometric tools to support the contention. It maintains that the choice of the country to impose selective capital controls for remedying the situation was efficacious, and proved fairly rewarding. I...

SPSS 9.0 for Windows 98/NT统计软件包简介

Institute of Scientific and Technical Information of China (English)

李志辉; 洪楠

2000-01-01

@@ SPSS(Statistical Package for the Social Science)是由美国SPSS公司自80年代初开发的大型统计学软件包.1998年推出的SPSS 9.0版本,除保持了以往SPSS的诸多优点以外,还汇集了SAS for Windows[1,2]与STATISTICA for Windows95/NT[3,4]的长处,是当今世界上最新、最流行、最受欢迎的统计软件包之一.与SPSS 7.5比较,SPSS 9.0具有以下新的特点[5].

Shock wave compression and self-generated electric field repolarization in ferroelectric ceramics Pb0.99[(Zr0.90Sn0.10)0.96Ti0.04]0.98Nb0.02O3

Science.gov (United States)

Jiang, Dongdong; Du, Jinmei; Gu, Yan; Feng, Yujun

2012-03-01

The shock wave induced depoling current of Pb0.99[(Zr0.90Sn0.10)0.96Ti0.04]0.98Nb0.02O3 ceramics was investigated with a system composed of a resistive load and an unpoled ceramic. Disparity in the depoling current was explained by considering the drawing charge effect of unpoled ceramic. The drawing effect for poled ceramics was analysed by developing a model incorporating a time- and electric-field-dependent repolarization. This model predicts that the high-impedance current eventually becomes higher than the short-circuit current, which is consistent with the experimental results in the literature. This work indicates that both the repolarization of uncompressed ceramics caused by the self-generated electric field and depolarization of compressed ceramics caused by the shock wave govern the output current.

Shock wave compression and self-generated electric field repolarization in ferroelectric ceramics Pb0.99[(Zr0.90Sn0.10)0.96Ti0.04]0.98Nb0.02O3

International Nuclear Information System (INIS)

Jiang Dongdong; Du Jinmei; Gu Yan; Feng Yujun

2012-01-01

The shock wave induced depoling current of Pb 0.99 [(Zr 0.90 Sn 0.10 ) 0.96 Ti 0.04 ] 0.98 Nb 0.02 O 3 ceramics was investigated with a system composed of a resistive load and an unpoled ceramic. Disparity in the depoling current was explained by considering the drawing charge effect of unpoled ceramic. The drawing effect for poled ceramics was analysed by developing a model incorporating a time- and electric-field-dependent repolarization. This model predicts that the high-impedance current eventually becomes higher than the short-circuit current, which is consistent with the experimental results in the literature. This work indicates that both the repolarization of uncompressed ceramics caused by the self-generated electric field and depolarization of compressed ceramics caused by the shock wave govern the output current. (paper)

CD147 and CD98 complex-mediated homotypic aggregation attenuates the CypA-induced chemotactic effect on Jurkat T cells.

Science.gov (United States)

Guo, Na; Zhang, Kui; Lv, Minghua; Miao, Jinlin; Chen, Zhinan; Zhu, Ping

2015-02-01

Homotypic cell aggregation plays important roles in physiological and pathological processes, including embryogenesis, immune responses, angiogenesis, tumor cell invasion and metastasis. CD147 has been implicated in most of these phenomena, and it was identified as a T cell activation-associated antigen due to its obvious up-regulation in activated T cells. However, the explicit function and mechanism of CD147 in T cells have not been fully elucidated. In this study, large and compact aggregates were observed in Jurkat T cells after treatment with the specific CD147 monoclonal antibody HAb18 or after the expression of CD147 was silenced by RNA interference, which indicated an inhibitory effect of CD147 in T cell homotypic aggregation. Knocking down CD147 expression resulted in a significant decrease in CD98, along with prominent cell aggregation, similar to that treated by CD98 and CD147 monoclonal antibodies. Furthermore, decreased cell chemotactic activity was observed following CD147- and CD98-mediated cell aggregation, and increased aggregation was correlated with a decrease in the chemotactic ability of the Jurkat T cells, suggesting that CD147- and CD98-mediated homotypic cell aggregation plays a negative role in T cell chemotaxis. Our data also showed that p-ERK, p-ZAP70, p-CD3ζ and p-LCK were significantly decreased in the CD147- and CD98-knocked down Jurkat T cells, which suggested that decreased CD147- and/or CD98-induced homotypic T cell aggregation and aggregation-inhibited chemotaxis might be associated with these signaling pathways. A role for CD147 in cell aggregation and chemotaxis was further indicated in primary CD4(+) T cells. Similarly, low expression of CD147 in primary T cells induced prominent cell aggregation and this aggregation attenuated primary T cell chemotactic ability in response to CypA. Our results have demonstrated the correlation between homotypic cell aggregation and the chemotactic response of T cells to CypA, and these data

Classification of the severe trauma patient with the Abbreviated Injury Scale: degree of correlation between versions 98 and 2005 (2008 update).

Science.gov (United States)

Abajas Bustillo, Rebeca; Leal Costa, César; Ortego Mate, María Del Carmen; Zonfrillo, Mark R; Seguí Gómez, María; Durá Ros, María Jesús

2018-02-01

To explore differences in severity classifications according to 2 versions of the Abbreviated Injury Scale (AIS): version 2005 (the 2008 update) and the earlier version 98. To determine whether possible differences might have an impact on identifying severe trauma patients. Descriptive study and cross-sectional analysis of a case series of patients admitted to two spanish hospitals with out-of-hospital injuries between February 2012 and February 2013. For each patient we calculated the Injury Severity Score (ISS), the New Injury Severity Score (NISS), and the AIS scores according to versions 98 and 2005. The sample included 699 cases. The mean Severity (SD) age of patients was 52.7 (29.2) years, and 388 (55.5%) were males. Version 98 of the AIS correlated more strongly with both the ISS (2.6%) and the NISS (2.9%). The 2008 update of the AIS (version 2005) classified fewer trauma patients than version 98 at the severity levels indicated by the ISS and NISS.

Carmen de Burgos, la APM y aquellas admirables chicas del 98

Directory of Open Access Journals (Sweden)

Hernando, Bernardino M.

2010-06-01

Full Text Available It enters the five women journalists pertaining to the Association of the Press of Madrid (APM was the writer, professor, lecturer and hardened travelling Carmen de Burgos, Colombine call. It and the other four, Jesusa Granda, participant in the foundation of the APM in 1895, Atocha Ossorio and Gallardo, Salomé Núñez de Topete and Consuelo Álvarez Pool trained a made an effort group of admirable women fighters by the culture and the human rights. Identified with the advanced to “generation of 98” if this nonhuibera be as chauvinistic as was almost everything then.

Entre las cinco primeras mujeres periodistas pertenecientes a la Asociación de la Prensa de Madrid (APM estaba la escritora, profesora, conferenciante y empedernida viajera Carmen de Burgos, llamada Colombine. Ella y las otras cuatro, Jesusa Granda, participante en la fundación de la APM en 1895, Atocha Ossorio y Gallardo, Salomé Núñez de Topete y Consuelo Álvarez Pool formaban un grupo esforzado de admirables mujeres luchadoras por la cultura y los derechos humanos. Identificadas con los ideales sociales más avanzados podrían haber pertenecido a la “generación del 98” si esta no hubiera sido tan machista como era casi todo en aquella época.

School District Revenues for Elementary and Secondary Education: 1997-98. Statistical Analysis Report.

Science.gov (United States)

Sherman, Joel D.; Gregory, Barbra; Poirier, Jeffrey M.

This report is an annual collection of school district financial data. Specifically, this report presents analyses of school district revenues from the 1997-98 school year. The report is designed to address the following questions about the financing of public elementary and secondary education at the state and district levels: How much money per…

1997/98 Orphan Well Fund annual report

International Nuclear Information System (INIS)

1999-04-01

Alberta's Orphan Well Fund (previously referred as the Abandonment Fund) is funded by the oil and gas industry with provincial government support and approval. It was created to enforce and improve regulations regarding orphan wells. 1997/98 marked the year in which Orphan Well Fund activities included pipeline abandonments, facility decommissioning, and well site reclamation. The first part of this report includes the annual report of the Orphan Fund, while the second part includes the report on the Energy and Utilities Board's (EUB's) Liability Management activities which are an important part of enforcing and improving provincial regulations in the prevention of orphan wells. The fund allows liability management to be done with industry's dollars rather than taxpayer's dollars. Highlights for the year include the successful completion on eleven downhole and surface wells. Expanded activities also included the abandonment of eleven pipelines, and facilities decommissioning work at five locations. The report also includes a financial review, and a summary of the future goals of the program. The EUB enforcement activities and operations, as well as the EUB orphan prevention activities are also reviewed. tabs

Metagenome sequencing and 98 microbial genomes from Juan de Fuca Ridge flank subsurface fluids

Science.gov (United States)

Jungbluth, Sean P.; Amend, Jan P.; Rappé, Michael S.

2017-03-01

The global deep subsurface biosphere is one of the largest reservoirs for microbial life on our planet. This study takes advantage of new sampling technologies and couples them with improvements to DNA sequencing and associated informatics tools to reconstruct the genomes of uncultivated Bacteria and Archaea from fluids collected deep within the Juan de Fuca Ridge subseafloor. Here, we generated two metagenomes from borehole observatories located 311 meters apart and, using binning tools, retrieved 98 genomes from metagenomes (GFMs). Of the GFMs, 31 were estimated to be >90% complete, while an additional 17 were >70% complete. Phylogenomic analysis revealed 53 bacterial and 45 archaeal GFMs, of which nearly all were distantly related to known cultivated isolates. In the GFMs, abundant Bacteria included Chloroflexi, Nitrospirae, Acetothermia (OP1), EM3, Aminicenantes (OP8), Gammaproteobacteria, and Deltaproteobacteria, while abundant Archaea included Archaeoglobi, Bathyarchaeota (MCG), and Marine Benthic Group E (MBG-E). These data are the first GFMs reconstructed from the deep basaltic subseafloor biosphere, and provide a dataset available for further interrogation.

Psalm 98: Sing 'n nuwe lied tot lof van die Koning, Jahwe | Prinsloo ...

African Journals Online (AJOL)

Sing a new song in praise of the king, Yahweh This article surveys the problems of interpreting Psalm 98. The chief problems are those concerned with determining the Gattung, the redactional history, strophic division and the dating of the Psalm. A textimmanent reading of the Psalm is used in an effort to make a significant ...

Contagion in the East: A Look at the 1997-98 Asian Financial Crisis.

Science.gov (United States)

Lee, Isadora; Lai, Selena; Francis, Gregory; Brunette, Rachel

The 1997-98 Asian financial crisis and its aftermath have brought to light a number of crucial economic lessons. This curriculum unit focuses on some of the purported causes of the crisis, the workings of the International Monetary Fund, and the general nature of economies affected by financial turmoil. Lesson 1, "A Story of Boom and Bust in…

Analysis of the legal aspects in public tender electronic made by PETROBRAS through the system Petronect under Decree no. 2.745/98; Analise da juridicidade das licitacoes eletronicas feitas pela PETROBRAS atraves do sistema Petronect nos termos do decreto 2.745/98

Energy Technology Data Exchange (ETDEWEB)

Prestes, Madelon Rocha Ribeiro [Transportadora Brasileira Gasoduto Bolivia-Brasil S.A. (TBG), Rio de Janeiro, RJ (Brazil)

2008-07-01

This work examines the question of possible of use an electronic tool through internet, the Petronect, to facilitate the completion of procedures to carry through licitations for the PETROBRAS Group that is being debated in diverse instances in the Brazilian present time. This analysis should take into account the existing law on licitations, the constitutionality of Decree 2.745/98, as well as economic facts. Due to the understanding of TCU - expressed on several occasions - in the sense that PETROBRAS would be required to use the Law 8.666/93 in its bids, is being challenged the constitutionality of Decree 2.745/98 and their use for licitations procedures. They will be examined the conceptual and legal aspects of the decree, and the relationship and the importance of the function for the Group Purchases damage. Thus, the analysis will cover the new issues raised by EC 19/98, the constitutionality of the decree, the position of the Court of Auditors of the Union and the Federal Supreme Court (STF) and the legislation published on this subject. The existing conclusion in this work shows how right - under the optical legal and constitutional - the use of the portal Petronect to carry out the licitations of PETROBRAS under Decree 2.745/98 and non-use of Law 8.666/93, for this is not appropriate to the specific activity of company. (author)

303-K Storage Facility: Report on FY98 closure activities

International Nuclear Information System (INIS)

Adler, J.G.

1998-01-01

This report summarizes and evaluates the decontamination activities, sampling activities, and sample analysis performed in support of the closure of the 303-K Storage Facility. The evaluation is based on the validated data included in the data validation package (98-EAP-346) for the 303-K Storage Facility. The results of this evaluation will be used for assessing contamination for the purpose of closing the 303-K Storage Facility as described in the 303-K Storage Facility Closure Plan, DOE/RL-90-04. The closure strategy for the 303-K Storage Facility is to decontaminate the interior of the north half of the 303-K Building to remove known or suspected dangerous waste contamination, to sample the interior concrete and exterior soils for the constituents of concern, and then to perform data analysis, with an evaluation to determine if the closure activities and data meet the closure criteria. The closure criteria for the 303-K Storage Facility is that the concentrations of constituents of concern are not present above the cleanup levels. Based on the evaluation of the decontamination activities, sampling activities, and sample data, determination has been made that the soils at the 303-K Storage Facility meet the cleanup performance standards (WMH 1997) and can be clean closed. The evaluation determined that the 303-K Building cannot be clean closed without additional closure activities. An additional evaluation will be needed to determine the specific activities required to clean close the 303-K Storage Facility. The radiological contamination at the 303-K Storage Facility is not addressed by the closure strategy

Effect of antiprogestin ZK 98.734 on the ovarian cycle, early pregnancy, and on its binding to progesterone receptors in the myometrium of marmoset Callithrix jacchus

International Nuclear Information System (INIS)

Puri, C.P.; Kholkute, S.D.; Pongubala, J.M.; Patil, R.K.; Elger, W.A.; Jayaraman, S.

1988-01-01

The antiprogestin ZK 98.734 (11 beta-(4-dimethylaminophenyl-17 beta-hydroxy-17 alpha-(3-hydroxy-prop-1(Z)-enyl-4,9(10)-estradien-3-one) was administered i.m. (5 mg/day) for three consecutive days to two groups of common marmosets. In one group (nonpregnant, n = 6), it was injected during the luteal phase, and to the second group (pregnant, n = 7), it was injected during early pregnancy, on Days 24-26 of the mid-cycle estradiol peak. Administration of ZK 98.734 during the luteal phase caused a sharp drop in plasma progesterone levels. The luteal phase was shortened whether the drug was administered during the early or the late luteal phase. Similarly, administration of ZK 98.734 during early pregnancy caused a significant drop in progesterone levels, and pregnancy was terminated in all of the animals. The post-treatment cycles in both groups of animals were ovulatory and of normal duration. 3 H-ZK 98.734 showed specific binding to myometrial cytosol fraction. ZK 98.734 also displaced the binding of 3 H-progesterone to progesterone receptors. However, progesterone had higher binding affinity than did ZK 98.734. The antifertility action of ZK 98.734 could be a result either of its luteolytic action or of its blocking the progesterone receptors in the target tissue. This study, therefore, indicates that in the common marmoset ZK 98.734 is a progesterone antagonist with a potential to terminate early pregnancy

Results of Review of the Implementation of Public Law 98-94 for Air Force Retirees

National Research Council Canada - National Science Library

1993-01-01

... of P.L. 98-94 was not fully implemented in a timely manner. We also believe there was no intentional disregard of the law by management at the Defense Finance and Accounting Service-Denver Center. Scope of Review...

The Effect of Z-Ligustilide on the Mobility of Human Glioblastoma T98G Cells.

Directory of Open Access Journals (Sweden)

Jun Yin

Full Text Available Z-ligustilide (LIG, an essential oil extract from Radix Angelica sinensis, has broad pharmaceutical applications in treating cardio-vascular diseases and ischemic brain injury. Recently, LIG has been connected to Glioblastoma multiforme (GBM because of its structural similarity to 3-n-alkyphthalide (NBP, which is specifically cytotoxic to GBM cells. Hence, we investigated LIG's effect on GBM T98G cells. The study shows that LIG can significantly reduce T98G cells' migration in a dose-dependent manner. Furthermore, the attenuation of cellular mobility can be linked to the activity of the Rho GTPases (RhoA, Rac1 and Cdc42, the three critical molecular switches governing cytoskeleton remodeling; thus, regulating cell migration. LIG significantly reduces the expression of RhoA and affects in a milder manner the expression of Cdc42 and Rac1.

Handbook: Collecting Groundwater Samples from Monitoring Wells in Frenchman Flat, CAU 98

Energy Technology Data Exchange (ETDEWEB)

Chapman, Jenny [Desert Research Inst. (DRI), Reno, NV (United States); Lyles, Brad [Desert Research Inst. (DRI), Reno, NV (United States); Cooper, Clay [Desert Research Inst. (DRI), Reno, NV (United States); Hershey, Ron [Desert Research Inst. (DRI), Reno, NV (United States); Healey, John [Desert Research Inst. (DRI), Reno, NV (United States)

2015-06-01

Frenchman Flat basin on the Nevada National Security Site (NNSS) contains Corrective Action Unit (CAU) 98, which is comprised of ten underground nuclear test locations. Environmental management of these test locations is part of the Underground Test Area (UGTA) Activity conducted by the U.S. Department of Energy (DOE) under the Federal Facility Agreement and Consent Order (FFACO) (1996, as amended) with the U.S. Department of Defense (DOD) and the State of Nevada. A Corrective Action Decision Document (CADD)/Corrective Action Plan (CAP) has been approved for CAU 98 (DOE, 2011). The CADD/CAP reports on the Corrective Action Investigation that was conducted for the CAU, which included characterization and modeling. It also presents the recommended corrective actions to address the objective of protecting human health and the environment. The recommended corrective action alternative is “Closure in Place with Modeling, Monitoring, and Institutional Controls.” The role of monitoring is to verify that Contaminants of Concern (COCs) have not exceeded the Safe Drinking Water Act (SDWA) limits (Code of Federal Regulations, 2014) at the regulatory boundary, to ensure that institutional controls are adequate, and to monitor for changed conditions that could affect the closure conditions. The long-term closure monitoring program will be planned and implemented as part of the Closure Report stage after activities specified in the CADD/CAP are complete. Groundwater at the NNSS has been monitored for decades through a variety of programs. Current activities were recently consolidated in an NNSS Integrated Sampling Plan (DOE, 2014). Although monitoring directed by the plan is not intended to meet the FFACO long-term monitoring requirements for a CAU (which will be defined in the Closure Report), the objective to ensure public health protection is similar. It is expected that data collected in accordance with the plan will support the transition to long-term monitoring at each

CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.

Science.gov (United States)

Fei, Fei; Li, Xiaofei; Xu, Li; Li, Deyang; Zhang, Zhipei; Guo, Xu; Yang, Hushan; Chen, Zhinan; Xing, Jinliang

2014-12-01

It has been reported that CD147 and CD98 heavy chain (CD98hc) form a complex on the cell plasma membrane of several cancers; however, whether this complex exists in non-small cell lung cancer (NSCLC) cells and affects the prognosis of patients remains to be elucidated. The expression of CD147 and CD98hc was assessed in tissue samples from 241 NSCLC patients and NSCLC cell lines. The correlation between CD147 and CD98hc expression and their association with the prognosis of NSCLC patients were analyzed. We also evaluated the impact of CD147 and CD98hc on the growth of NSCLC cells as well as Akt phosphorylation. Both CD147 and CD98hc were significantly upregulated in NSCLC cells, and their expression levels were significantly correlated (p CD147 and CD98hc could form a complex on NSCLC cells. Compared with NSCLC patients with CD147-/CD98hc-, those with CD147+/CD98hc+ exhibited a significantly poor overall survival (OS) with a hazard ratio (HR) of 1.92 (p = 0.010), and a significantly increased risk of recurrence with a HR of 1.97 (p = 0.004). Also, we demonstrated that the proliferation of lung cancer cell lines was significantly affected by knockdown and force-expression of the CD147-CD98hc complex. Western blot analysis indicated that the phosphorylation of Akt in NSCLC cells was significantly affected by knockdown and overexpression of either or both CD147 and CD98hc. Our findings indicate that the CD147-CD98hc complex significantly contributes to poor prognosis of NSCLC patients through promoting cell proliferation via the PI3K/Akt pathway.

Sensitive lifetime measurement of excited states of {sup 98}Ru via the (p,p{sup '}γ) reaction

Energy Technology Data Exchange (ETDEWEB)

Vielmetter, Vera; Hennig, Andreas; Derya, Vera; Pickstone, Simon G.; Prill, Sarah; Spieker, Mark; Zilges, Andreas [Institute for Nuclear Physics, University of Cologne (Germany); Petkov, Pavel [Institute for Nuclear Physics, University of Cologne (Germany); INRNE, Bulgarian Academy of Sciences, Sofia (Bulgaria); National Institute for Physics and Nuclear Engineering, Bucharest-Magurele (Romania)

2016-07-01

The one-phonon mixed-symmetry quadrupole excitation 2{sup +}{sub ms} is a well established excitation mode in near-spherical nuclei, especially in the A ∼ 100 mass region. However, it is largely unknown how mixed-symmetry states evolve along shape-transitional paths, e.g. from spherical to deformed shapes. The chain of stable ruthenium isotopes is well suited for this study since it exhibits a smooth transition from spherical ({sup 96,98}Ru) to deformed shapes ({sup 104}Ru). To identify the 2{sup +}{sub ms} state of {sup 98}Ru on the basis of absolute M1 and E2 transition strengths, we performed a proton-scattering experiment on {sup 98}Ru using the SONIC rate at HORUS setup at the University of Cologne. Lifetimes of excited states were measured via the Doppler-shift attenuation method (DSAM), which benefits from the acquired pγ-coincidence data. First results of this experiment are presented and compared to the neighbouring nuclei {sup 96}Ru and {sup 100}Ru.

Corporate plan 1997/98 to 2001/02

International Nuclear Information System (INIS)

1997-01-01

The National Radiological Protection Board is a public authority established by the Radiological Protection Act 1970 with functions concerning the protection of people from radiation hazards. Members of the Board are appointed by the Health Ministers. Officers and employees of the Board are responsible to it for executing the functions. The Board produces a Corporate Plan which is presented to the Department of Health, its sponsoring Department. This is the Corporate Plan for 1997/98 and the subsequent four years to 2001/02. It follows from discussions with Government Departments and other customers and reflects Ministerial priorities. It also takes into account the recommendations of the recent Cabinet Office publication on Objective Setting and Monitoring in Executive Non-Departmental Public Bodies prepared by the Efficiency Unit. And it reflects the outcome of the recent Prior Options Review of the Board. The main purposes of the Corporate Plan are to describe the broad programme of work for the planning period and the manner in which it is to be implemented, to identify the strategic and specific objectives, and to make the necessary financial forecasts. (author)

Morphology and segmentation of the western Galápagos Spreading Center, 90.5°-98°W: Plume-ridge interaction at an intermediate spreading ridge

Science.gov (United States)

Sinton, John; Detrick, Robert; Canales, J. Pablo; Ito, Garrett; Behn, Mark

2003-12-01

Complete multibeam bathymetric coverage of the western Galápagos Spreading Center (GSC) between 90.5°W and 98°W reveals the fine-scale morphology, segmentation and influence of the Galápagos hot spot on this intermediate spreading ridge. The western GSC comprises three morphologically defined provinces: A Western Province, located farthest from the Galápagos hot spot west of 95°30'W, is characterized by an axial deep, rift valley morphology with individual, overlapping, E-W striking segments separated by non-transform offsets; A Middle Province, between the propagating rift tips at 93°15'W and 95°30'W, with transitional axial morphology strikes ˜276°; An Eastern Province, closest to the Galápagos hot spot between the ˜90°50'W Galápagos Transform and 93°15'W, with an axial high morphology generally less than 1800 m deep, strikes ˜280°. At a finer scale, the axial region consists of 32 individual segments defined on the basis of smaller, mainly lower overall magma supply and larger offset distance at the latter. The structure of the Eastern Province is complicated by the intersection of a series of volcanic lineaments that appear to radiate away from a point located on the northern edge of the Galápagos platform, close to the southern limit of the Galápagos Fracture Zone. Where these lineaments intersect the GSC, the ridge axis is displaced to the south through a series of overlapping spreading centers (OSCs); abandoned OSC limbs lie even farther south. We propose that southward displacement of the axis is promoted during intermittent times of increased plume activity, when lithospheric zones of weakness become volcanically active. Following cessation of the increased plume activity, the axis straightens by decapitating southernmost OSC limbs during short-lived propagation events. This process contributes to the number of right stepping offsets in the Eastern Province.

Relation between chemical properties in molten acetamide and water at 98 deg. C

International Nuclear Information System (INIS)

Petit, Nicole

1972-01-01

An attempt was made to establish the relation between the chemical properties of various cations in water and in molten acetamide at 98 deg. C. A solvent always possesses properties which have some effect on the reactivity of the solute. Various types of interactions (polar, electrostatic, Van der Waals forces, and hydrogen bonds) bind the solvent molecules to the dissolved molecules and ions. Interactions between the solute species and the solvent species are designated: solvation phenomena. In addition to solvation phenomena, another but less direct type of interaction occurs: the solvated ions find themselves in a sensibly continuous medium having a dielectric constant ε which can vary considerably. As the value of the dielectric constant decreases, the electrostatic interactions between the ions increase. The variation is such that these ions can only be considered free for values of ε > 40. This is the case for acetamide and water at 98 deg. C. The solvation of a chemical species belonging to an oxido-reducing system can only be effected by comparing the behavior of such a system with a reference system relatively insensitive to changes in the solvent. The reference system used was a ferrocene-ion/ferricinium couple. The solvation of a chemical species is characterized by a variable designated: the solvation activity coefficient. The chemical and electrochemical properties of various elements (alkali elements, alkaline earths, Cu, Zn, Cd, Hg, Pb, U, Al, Ce, and Eu) in neutral or acid media in acetamide were studied using various electrochemical techniques (principally polarography). These studies led to the establishment of a table of oxido-reducing potentials for molten acetamide. Comparisons with water at 98 deg. C indicate that the metallic cations are more solvated in acetamide than in water. The evaluation of solvation activity coefficients from polarographic measurements (E 1/2 , D M ) led to an approximate estimation of the differences in behavior

Shape Evolution in Neutron-Rich Krypton Isotopes Beyond N=60: First Spectroscopy of ^{98,100}Kr.

Science.gov (United States)

Flavigny, F; Doornenbal, P; Obertelli, A; Delaroche, J-P; Girod, M; Libert, J; Rodriguez, T R; Authelet, G; Baba, H; Calvet, D; Château, F; Chen, S; Corsi, A; Delbart, A; Gheller, J-M; Giganon, A; Gillibert, A; Lapoux, V; Motobayashi, T; Niikura, M; Paul, N; Roussé, J-Y; Sakurai, H; Santamaria, C; Steppenbeck, D; Taniuchi, R; Uesaka, T; Ando, T; Arici, T; Blazhev, A; Browne, F; Bruce, A; Carroll, R; Chung, L X; Cortés, M L; Dewald, M; Ding, B; Franchoo, S; Górska, M; Gottardo, A; Jungclaus, A; Lee, J; Lettmann, M; Linh, B D; Liu, J; Liu, Z; Lizarazo, C; Momiyama, S; Moschner, K; Nagamine, S; Nakatsuka, N; Nita, C; Nobs, C R; Olivier, L; Orlandi, R; Patel, Z; Podolyák, Zs; Rudigier, M; Saito, T; Shand, C; Söderström, P A; Stefan, I; Vaquero, V; Werner, V; Wimmer, K; Xu, Z

2017-06-16

We report on the first γ-ray spectroscopy of low-lying states in neutron-rich ^{98,100}Kr isotopes obtained from ^{99,101}Rb(p,2p) reactions at ∼220  MeV/nucleon. A reduction of the 2_{1}^{+} state energies beyond N=60 demonstrates a significant increase of deformation, shifted in neutron number compared to the sharper transition observed in strontium and zirconium isotopes. State-of-the-art beyond-mean-field calculations using the Gogny D1S interaction predict level energies in good agreement with experimental results. The identification of a low-lying (0_{2}^{+}, 2_{2}^{+}) state in ^{98}Kr provides the first experimental evidence of a competing configuration at low energy in neutron-rich krypton isotopes consistent with the oblate-prolate shape coexistence picture suggested by theory.

75 FR 54226 - Proposed Collection; Comment Request for Notice 98-52 and REG-108639-99

Science.gov (United States)

2010-09-03

... Notice 98-52 and REG- 108639-99 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and... proposed rulemaking, REG-108639-99, Retirement Plans; Cash or Deferred Arrangements Under Section 401(k.... Regulation Project Number: REG-108639-99. Abstract: This notice provides guidance to plan administrators...

Continuously increasing δ98Mo values in Neoarchean black shales and iron formations from the Hamersley Basin

Science.gov (United States)

Kurzweil, Florian; Wille, Martin; Schoenberg, Ronny; Taubald, Heinrich; Van Kranendonk, Martin J.

2015-09-01

We present Mo-, C- and O-isotope data from black shales, carbonate- and oxide facies iron formations from the Hamersley Group, Western Australia, that range in age from 2.6 to 2.5 billion years. The data show a continuous increase from near crustal δ98Mo values of around 0.50‰ for the oldest Marra Mamba and Wittenoom formations towards higher values of up to 1.51‰ for the youngest sample of the Brockman Iron Formation. Thereby, the trend in increasing δ98Mo values is portrayed by both carbonate facies iron formations and black shales. Considering the positive correlation between Mo concentration and total organic carbon, we argue that this uniformity is best explained by molybdate adsorption onto organic matter in carbonate iron formations and scavenging of thiomolybdate onto sulfurized organic matter in black shales. A temporal increase in the seawater δ98Mo over the period 2.6-2.5 Ga is observed assuming an overall low Mo isotope fractionation during both Mo removal processes. Oxide facies iron formations show lowest Mo concentrations, lowest total organic carbon and slightly lower δ98Mo compared to nearly contemporaneous black shales. This may indicate that in iron formation settings with very low organic matter burial rates, the preferential adsorption of light Mo isotopes onto Fe-(oxyhydr)oxides becomes more relevant. A similar Mo-isotope pattern was previously found in contemporaneous black shales and carbonates of the Griqualand West Basin, South Africa. The consistent and concomitant increase in δ98Mo after 2.54 billion years ago suggests a more homogenous distribution of seawater molybdate with uniform isotopic composition in various depositional settings within the Hamersley Basin and the Griqualand West Basin. The modeling of the oceanic Mo inventory in relation to the Mo in- and outflux suggests that the long-term build-up of an isotopically heavy seawater Mo reservoir requires a sedimentary sink for isotopically light Mo. The search for this

Ethological parameters and performance of Hy Line W-98 and ISA Brown hens when housed in furnished cages Parâmetros etológicos e desempenho de poedeiras Hy line W-98 e Isa Brown alojadas em gaiolas enriquecidas

Directory of Open Access Journals (Sweden)

V.F.B. Roll

2008-06-01

Full Text Available This study was carried out throughout a laying period to compare the behaviour and performance of two groups of commercial layers, 180 ISA Brown and 120 Hy line W98, housed at 17 weeks of age in furnished cages with a nest box, perches, dust-bath, and claw shortening device. Based on productive parameters, the model of furnished cages studied is suitable for both, Isa Brown and Hy line hens. The study suggested that strain has a significant effect on feather condition and on some behavioural displays, particularly those related to the use of a dust-bath.Durante um ciclo completo de postura foram avaliados o comportamento e o desempenho de duas linhagens de poedeiras comerciais, 180 ISA Brown e 120 Hy line W98, alojadas com 17 semanas de idade em gaiolas enriquecidas com ninho, poleiros, banho de areia e dispositivos de desgaste de unhas. Em ambas as linhagens, Isa Brown e Hy line W98, o modelo de gaiola estudado foi apropriado em termos de desempenho produtivo. O estudo sugeriu que a linhagem teve efeito significativo sobre a condição da plumagem e sobre alguns aspectos comportamentais, particularmente, aqueles relacionados ao uso do banho de areia.

Genes involved in degradation of para-nitrophenol are differentially arranged in form of non-contiguous gene clusters in Burkholderia sp. strain SJ98.

Directory of Open Access Journals (Sweden)

Surendra Vikram

Full Text Available Biodegradation of para-Nitrophenol (PNP proceeds via two distinct pathways, having 1,2,3-benzenetriol (BT and hydroquinone (HQ as their respective terminal aromatic intermediates. Genes involved in these pathways have already been studied in different PNP degrading bacteria. Burkholderia sp. strain SJ98 degrades PNP via both the pathways. Earlier, we have sequenced and analyzed a ~41 kb fragment from the genomic library of strain SJ98. This DNA fragment was found to harbor all the lower pathway genes; however, genes responsible for the initial transformation of PNP could not be identified within this fragment. Now, we have sequenced and annotated the whole genome of strain SJ98 and found two ORFs (viz., pnpA and pnpB showing maximum identity at amino acid level with p-nitrophenol 4-monooxygenase (PnpM and p-benzoquinone reductase (BqR. Unlike the other PNP gene clusters reported earlier in different bacteria, these two ORFs in SJ98 genome are physically separated from the other genes of PNP degradation pathway. In order to ascertain the identity of ORFs pnpA and pnpB, we have performed in-vitro assays using recombinant proteins heterologously expressed and purified to homogeneity. Purified PnpA was found to be a functional PnpM and transformed PNP into benzoquinone (BQ, while PnpB was found to be a functional BqR which catalyzed the transformation of BQ into hydroquinone (HQ. Noticeably, PnpM from strain SJ98 could also transform a number of PNP analogues. Based on the above observations, we propose that the genes for PNP degradation in strain SJ98 are arranged differentially in form of non-contiguous gene clusters. This is the first report for such arrangement for gene clusters involved in PNP degradation. Therefore, we propose that PNP degradation in strain SJ98 could be an important model system for further studies on differential evolution of PNP degradation functions.

License - RGP gmap98 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us RGP gmap98 License License to Use This Database Last updated : 2015/02/12 You may use this database...e license terms regarding the use of this database and the requirements you must follow in using this database.... The license for this database is specified in the Creative Commons Attributio...n-Share Alike 2.1 Japan . If you use data from this database, please be sure attribute this database as foll...on-Share Alike 2.1 Japan is found here . With regard to this database, you are licensed to: freely access part or whole of this datab

S. Afr. Tydskr. Veek. I I , 2BS -286 ( I 98 I ) NAVORSINGSBERIG DIE ...

African Journals Online (AJOL)

Die produksie van lusernhooi het toegeneem vanaf. 448 000 ton in die l95ll52 seisoen tot | 254 000 ton in die 1979180 seisoen (Kortbegrip van l-andboustati- stiek, l98l). Verder is dit insiggewend om daarop te let dat lusemhooi nagenoeg3g/' bydra tot die hoeveelheid proteibne geproduseer uit die proteibnryke voersoorte ...

Fugemateriale til belægningssten og fliser

DEFF Research Database (Denmark)

Larsen, Kristian

2004-01-01

Der anlægges ca. 9 millioner kvadratmeter belægning i betonsten og fliser om året i Danmark. Fugearealet udgør gennemsnitlig 4 %, svarende til et areal på ca. 36 ha.......Der anlægges ca. 9 millioner kvadratmeter belægning i betonsten og fliser om året i Danmark. Fugearealet udgør gennemsnitlig 4 %, svarende til et areal på ca. 36 ha....

Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases.

Science.gov (United States)

Melchior, Aurélie; Denys, Agnès; Deligny, Audrey; Mazurier, Joël; Allain, Fabrice

2008-02-01

Initially identified as a cyclosporin-A binding protein, cyclophilin B (CyPB) is an inflammatory mediator that induces adhesion of T lymphocytes to fibronectin, by a mechanism dependent on CD147 and alpha 4 beta 1 integrins. Recent findings have suggested that another cell membrane protein, CD98, may cooperate with CD147 to regulate beta1 integrin functions. Based on these functional relationships, we examined the contribution of CD98 in the pro-adhesive activity of CyPB, by utilizing the responsive promonocyte cell line THP-1. We demonstrated that cross-linking CD98 with CD98-AHN-18 antibody mimicked the responses induced by CyPB, i.e. homotypic aggregation, integrin-mediated adhesion to fibronectin and activation of p44/42 MAPK. Consistent with previous data, immunoprecipitation confirmed the existence of a heterocomplex wherein CD147, CD98 and beta1 integrins were associated. We then demonstrated that CyPB-induced cell adhesion and p44/42 MAPK activation were dependent on the participation of phosphoinositide 3-kinase and subsequent activation of protein kinase C-delta. Finally, silencing the expression of CD98 by RNA interference potently reduced CyPB-induced cell responses, thus confirming the role of CD98 in the pro-adhesive activity of CyPB. Altogether, our results support a model whereby CyPB induces integrin-mediated adhesion via interaction with a multimolecular unit formed by the association between CD147, CD98 and beta1 integrins.

Particle deposition and clearance of atmospheric particles in the human respiratory tract during LACE 98

Science.gov (United States)

Bundke, U.; Hänel, G.

2003-04-01

During the LACE 98footnote{Lindenberg Aerosol Characterization Experiment, (Germany) 1998} experiment microphysical, chemical and optical properties of atmospheric particles were measured by several groups. (Bundke et al.). The particle deposition and clearance of the particles in the human respiratory tract was calculated using the ICRP (International Commission on Radiological Protection) deposition and clearance model (ICRP 1994). Particle growth as function of relative humidity outside the body was calculated from measurement data using the model introduced by Bundke et al.. Particle growth inside the body was added using a non-equilibrium particle growth model. As a result of the calculations, time series of the total dry particle mass and -size distribution were obtained for all compartments of the human respiratory tract defined by ICRP 1994. The combined ICRP deposition and clearance model was initialized for different probationers like man, woman, children of different ages and several circumstances like light work, sitting, sleeping etc. Keeping the conditions observed during LACE 98 constant a approximation of the aerosol burdens of the different compartments was calculated up to 4 years of exposure and compared to the results from Snipes et al. for the "Phoenix" and "Philadelphia" aerosol. References: footnotesize{ Bundke, U. et al.,it{Aerosol Optical Properties during the Lindenberg Aerosol Characterization Experiment (LACE 98)} ,10.1029/2000JD000188, JGR, 2002 ICRP,it{Human Respiratory Tract Model for Radiological Protection, Bd. ICRP Publication 66}, Annals of the ICRP, 24,1-3, Elsevier Science, Ocford, 1994 Snipes et al. ,it{The 1994 ICRP66 Human Respiratory Tract Model as a Tool for predicting Lung Burdens from Exposure to Environmental Aerosols}, Appl. Occup. Environ. Hyg., 12, 547-553,1997}

PEMBINAAN PRESTASI CABANG OLAHRAGA TARUNG DERAJAT DI SATLAT GOR SATRIA KABUPATEN BANYUMAS TAHUN 2013

Directory of Open Access Journals (Sweden)

Fajar Yulianto

2015-02-01

Full Text Available From the research, the results showed that the implementation of the coaching is done on pemassalan coaching experience problems due to sports Tarung Derajat can not be socialized. Facilities and infrastructure owned by the club is not entirely adequate, and additional facilities and infrastructure necessary to support the exercise. The proceeds of the club is the Sports Committee, donors, administrators, and athletes. Conducted training programs already running smoothly, the coach has given a program of physical exercise, technique, mental, and tactics. The coach who handles the coaching process in Satlat GOR Satria amounted to only one person. In the process of selecting athletes to represent the area of selection must be made not just recruit great athletes from other regions. Achievement owned Satlat GOR Satria Banyumas is in Porprov in 2013, dulongmas, Kejurkab and Kejurda.

Direct observation of an isomeric state in {sup 98}Rb and nuclear properties of exotic rubidium isotopes measured by laser spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Procter, T.J.; Garnsworthy, A.B.; Levy, C.D.P.; Pearson, M.R. [TRIUMF, Vancouver, British Columbia (Canada); Behr, J.A.; Dilling, J. [TRIUMF, Vancouver, British Columbia (Canada); University of British Columbia, Department of Physics, Vancouver, British Columbia (Canada); Billowes, J. [The University of Manchester, School of Physics and Astronomy, Manchester (United Kingdom); Buchinger, F.; Crawford, J.E.; Leary, A.; Shelbaya, O.; Al Tamimi, W. [McGill University, Physics Department, Montreal, Quebec (Canada); Cheal, B. [University of Liverpool, Department of Physics, Liverpool (United Kingdom); Mane, E. [TRIUMF, Vancouver, British Columbia (Canada); Ministry of External Relations, Rio Bianco Institute, Brasilia (Brazil); Stolz, M. [Technische Universitaet Berlin, Berlin (Germany); Voss, A. [TRIUMF, Vancouver, British Columbia (Canada); University of Jyvaeskylae, Department of Physics, Jyvaeskylae (Finland)

2015-02-01

Fast-beam collinear laser spectroscopy experiments on rubidium have been performed at the ISAC radioactive ion beam facility at TRIUMF. Most recently, the neutron-rich {sup 98}Rb isotope has been studied for the investigation of shape coexistence. Two long-lived nuclear states in {sup 98}Rb have been clearly observed for the first time: a low-spin state, assigned a spin of I = 0, and a high-spin state. The high-spin state is tentatively assigned a spin of I = 3 based on this analysis in combination with gamma decay results. The measured nuclear properties of the two states are presented, alongside unpublished values of the neutron-deficient isotopes investigated previously. The mean-square charge radii of both states in {sup 98}Rb are observed to continue along the isodeformation line present after the N = 60 onset of deformation. (orig.)

Socioeconomic Research on Fusion. SERF 1997-98

Energy Technology Data Exchange (ETDEWEB)

Saez, R.; Lechon, Y.; Cabal, H.; Lomba, L.; Palomino, I.; Recreo, F.; Robles, B.; Suanez, A.; Cancio, D. [Ciemat. Madrid (Spain)

1999-09-01

In this study the environmental externalities produced in some stages of a hypothetical fusion power plant have been studied. The results are the CIEMAT contribution in the macro task named External costs and benefits of the Socioeconomic Research on Fusion (SERF 1997-98) European project. For the externalities economical assessment the Externe methodology has been applied. Lauffen, sited in the SW of Germany has been selected as the hypothetical location of the power plant. The technology, for two different models, was described by Max Planck Institute and the externalities of the materials manufacturing, power plant construction and operation as well as accidents have been monetarily evaluated. The obtained results revealed that for the plant model which uses cooling water, the prevalent cause of external costs were collective doses produced by the global dispersion of 14C emissions. External costs produced by radiological accidents represent low values, however the preliminary assessment performed for the external impacts caused by the ingestion of contaminated foodstuff and water, point out that a more detailed analysis for this stage, is needed. It should be noted that the results presented in this study, are partial values since other potentially important stages such as disposal of radiological waste and decommissioning of the power plant, have not been included. (Author)

Proceedings of the workshop on severe accident research held in Japan (SARJ-98)

Energy Technology Data Exchange (ETDEWEB)

Sugimoto, Jun [ed.

1999-07-01

The Workshop on Severe Accident Research held in Japan (SARJ-98) was taken place at Hotel Lungwood on November 4-6, 1998, and attended by 181 participants from 13 countries. The 63 papers, which cover wide areas of severe accident research both in experiments and analyses, such as in-vessel melt retention, fuel-coolant interaction, fission products behavior, structural integrity, containment behavior, computer simulations, and accident management, are indexed individually. (J.P.N.)

Histological evaluation of bovine tunica albuginea as biomaterial conserved in 98% glycerin and in 0.625% glutaraldehyde

Directory of Open Access Journals (Sweden)

Leticia Leal Oliveira

2015-12-01

Full Text Available ABSTRACT. Oliveira L.L., Barata J.S., Silva A.V.P., Caravalho E.C.Q., Nunes L.C. & Abílio E.J. [Histological evaluation of bovine tunica albuginea as biomaterial conserved in 98% glycerin and in 0.625% glutaraldehyde.] Avaliação histológica da túnica albugínea bovina como biomaterial conservada em glicerina a 98% e em glutaraldeído a 0,625%. Revista Brasileira de Medicina Veterinária, 37(4:309-315, 2015. Departamento de Medicina Veterinária, Universidade Federal do Espírito Santo, Alto Universitário s/n, Guararema, Alegre, ES 29500-000, Brasil. E-mail: leticialealolive@hotmail.com Biomaterials have long been studied in reconstructive surgery, both natural and synthetic origin. It can be used as support to host tissue cells development and an efficient bed of stem cells for tissue engineering and regeneration of tissues and organs. The aim of this study was to evaluate the tunica albuginea as biomaterial preserved in glycerin 98% and glutaraldehyde 0.625% and analyze its integrity for use in grafting therapy by microscopic examinations. Tunica albuginea were obtained from healthy adults crossbred cattle from slaughterhouse, tunicas albugineas were preserved in 98% glycerin and 0.625% glutaraldehyde for a period of 30 days at least. Tunica albuginea was fixed in 10% formalin, histologically processed and stained by hematoxylin-eosin, Masson’s trichrome and red picrosisrius polarization. Macroscopically there was a difference in the texture and color of tunica albuginea and in glutaraldehyde group were more firm and thick. Microscopic evaluation revealed that both the glycerin and the glutaraldehyde can be used as conservation medium in function of preserving the basic architecture tissue of the tunica albuginea, however, the glycerin was more efficient preservation of cellular structures. Histochemical techniques have highlighted the collagen and elastic fibers present in tunicas albugineas and highlight the predominance of type I

Recoil-distance lifetime measurements in 96,97,98Ru: Search for possible onset of collectivity at N≥52

International Nuclear Information System (INIS)

Kharraja, B.; Garg, U.; Ghugre, S. S.; Jin, H.; Janssens, R. V. F.; Ahmad, I.; Amro, H.; Carpenter, M. P.; Fischer, S.; Khoo, T. L.

2000-01-01

Lifetimes of high-spin states in the N=52-54 Ru nuclei have been investigated via the 65 Cu( 36 S,pyn) 96,97,98 Ru (y=4,3,2) reactions using the recoil-distance Doppler-shift technique. The data were collected in coincidence mode. Lifetimes have been extracted for both the positive- and the negative-parity states in 96 Ru and 98 Ru and for the positive-parity states in 97 Ru. The levels studied have lifetimes in the range 2-31 ps. The observed reduced transition probabilities B(E2) and B(M1) are compared with the predictions of the shell model. Theoretical implications of these results are discussed. (c) 1999 The American Physical Society

Sexual Harassment Law after the 1997-98 U.S. Supreme Court Term. [School Boards Liability].

Science.gov (United States)

Shaw, Brian C.; Hyde, W. Brent

1998-01-01

During its 1997-98 term, the U.S. Supreme Court decided four major sexual harassment cases. This article summarizes those cases' impact on the analytical framework governing school boards' liability of sexual harassment. The text opens with the issue of sexual harassment of employees by supervisors and two cases that established new standards…

The AUSGeoid98 geoid model of Australia: data treatment, computations and comparisons with GPS-levelling data

DEFF Research Database (Denmark)

Featherstone, W.E.; Kirby, J.F.; Kearsley, A.H.W.

2001-01-01

The AUSGeoid98 gravimetric geoid model of Australia has been computed using data from the EGM96 global geopotential model, the 1996 release of the Australian gravity database, a nationwide digital elevation model, and satellite altimeter-derived marine gravity anomalies. The geoid heights are on ...

The Genetically Remote Pathogenic Strain NVH391-98 of the Bacillus cereus Group Represents the Cluster of Thermophilic Strains

Energy Technology Data Exchange (ETDEWEB)

Auger, Sandrine; Galleron, Nathalie; Bidnenko, Elena; Ehrlich, S. Dusko; Lapidus, Alla; Sorokin, Alexei

2007-10-02

Bacteria of the Bacillus cereus group are known to cause food poisoning. A rare phylogenetically remote strain, NVH391-98, was recently characterized to encode a particularly efficient cytotoxin K presumably responsible for food poisoning. This pathogenic strain and its close relatives can be phenotypically distinguished from other strains of the B. cereus group by the inability to grow at temperatures below 17 degrees C and by the ability to grow at temperatures from 48 to 53 degrees C. A temperate phage, phBC391A2, residing in the genome of NVH391-98 allows us to distinguish the three known members of this thermophilic strain cluster.

Influence of high-energy ion implantation on the microstructure of Sn - 9,8 wt. % Zn alloy

International Nuclear Information System (INIS)

Gusakova, O.V.

2016-01-01

The results of investigation of influence of Xe ion implantation on the microstructure of Sn - 9,8 wt. % Zn alloy are represented/ Analysis of the experimental results shows that the high-energy ion implantation of Xe causes a change in the particle size of zinc. (authors)

Outcomes of special histotypes of breast cancer after adjuvant endocrine therapy with letrozole or tamoxifen in the monotherapy cohort of the BIG 1-98 trial

DEFF Research Database (Denmark)

Munzone, E; Giobbie-Hurder, A; Gusterson, B A

2015-01-01

BACKGROUND: We investigated the outcomes of postmenopausal women with hormone receptor-positive, early breast cancer with special histotypes (mucinous, tubular, or cribriform) enrolled in the monotherapy cohort of the BIG 1-98 trial. PATIENTS AND METHODS: The intention-to-treat BIG 1-98 monothera...

Socioeconomic Research on Fusion. Serf 1997-98

International Nuclear Information System (INIS)

Saez, R.; Lechon, Y.; Cabal, H.; Lomba, L.; Palomino, I.; Recreo, F.; Robles, B.; Suanez, A.; Cancio, D.

1999-01-01

Tin this study the environmental externalisation produced in some stages of a hypothetical fusion power plant have been studied. The results are the CIEMAT contribution in the macro task named External costs and benefits of the Socioeconomic Research on Fusion (SERF 1997-98) European project. For the externalisation economical assessment the Externe methodology has been applied. Lauffen, sited in the SW of Germany has been selected as the hypothetical location of the power plant. The technology, for two different models, was described by Max Planck Institute and the externalisation of the materials manufacturing, power plant construction and operation as well as accidents have been monetarily evaluated. The obtained results revealed that for the plant model which uses cooling water, the prevalent cause of external costs were the collective doses produced by the global dispersion of 14C emissions. External costs produced by radiological accidents represent low values, however the preliminary assessment performed for the external impacts caused by the ingestion of contaminated food stuff and water, point out that a more detailed analysis for this stage, is needed. It should be noted that the results presented in this study, are partial values since other potentially important stages such as disposal of radiological waste and decommissioning of the power plant, have not been included. (Author) 30 refs

Experimental Observation of Anisotropic Adler-Bell-Jackiw Anomaly in Type-II Weyl Semimetal WTe1.98 Crystals at the Quasiclassical Regime

Science.gov (United States)

Lv, Yang-Yang; Li, Xiao; Zhang, Bin-Bin; Deng, W. Y.; Yao, Shu-Hua; Chen, Y. B.; Zhou, Jian; Zhang, Shan-Tao; Lu, Ming-Hui; Zhang, Lei; Tian, Mingliang; Sheng, L.; Chen, Yan-Feng

2017-03-01

The asymmetric electron dispersion in type-II Weyl semimetal theoretically hosts anisotropic transport properties. Here, we observe the significant anisotropic Adler-Bell-Jackiw (ABJ) anomaly in the Fermi-level delicately adjusted WTe1.98 crystals. Quantitatively, CW , a coefficient representing the intensity of the ABJ anomaly along the a and b axis of WTe1.98 are 0.030 and 0.051 T-2 at 2 K, respectively. We found that the temperature-sensitive ABJ anomaly is attributed to a topological phase transition from a type-II Weyl semimetal to a trivial semimetal, which is verified by a first-principles calculation using experimentally determined lattice parameters at different temperatures. Theoretical electrical transport study reveals that the observation of an anisotropic ABJ along both the a and b axes in WTe1.98 is attributed to electrical transport in the quasiclassical regime. Our work may suggest that electron-doped WTe2 is an ideal playground to explore the novel properties in type-II Weyl semimetals.

Onset of collectivity in $^{96,98}$Sr studied via Coulomb excitation

CERN Document Server

Clement, E; Dijon, A; de France, G; Bastin, B; Blazhev, A; Bree, N; Butler, P; Delahaye, P; Ekstrom, A; Georgiev, G; Hasan, N; Iwanicki, J; Jenkins, D; Korten, W; Larsen, A C; Ljungvall, J; Moschner, K; Napiorkowski, P; Pakarinen, J; Petts, A; Renstrom, T; Seidlitz, M; Siem, S; Sotty, C; Srebrny, J; Stefanescu, I; Tveten, G M; Van de Walle, J; Warr, N; Wrzosek-Lipska, K; Zielinska, M; Bauer, C; Bruyneel, B; Butterworth, J; Fitzpatrick, C; Fransen, C; GernhäUser, R; Hess, H; Lutter, R; Marley, P; Reiter, P; Siebeck, B; Vermeulen, M; Wiens, A; De Witte, H

2014-01-01

A rapid onset of quadrupole deformation is known to occur around the neutron number 60 in the neutron-rich Zr and Sr isotopes. This shape change has made the neutron-rich A = 100 region an active area of experimental and theoretical studies for many decades now. We report in this contribution new experimental results in the neutron rich 96,98Sr investigated by safe Coulomb excitation of radioactive beams at the REX-ISOLDE facility, CERN. Reduced transition probabilities and spectroscopic quadrupole moments have been extracted from the differential Coulomb excitation cross section supporting the scenario of shape coexistence/change at N=60. Future perspectives are presented including the recent experimental campaign performed at ILL-Grenoble.

Onset of collectivity in 96,98Sr studied via Coulomb excitation

Directory of Open Access Journals (Sweden)

Clément E.

2014-03-01

Full Text Available A rapid onset of quadrupole deformation is known to occur around the neutron number 60 in the neutron-rich Zr and Sr isotopes. This shape change has made the neutron-rich A = 100 region an active area of experimental and theoretical studies for many decades now. We report in this contribution new experimental results in the neutron rich 96,98Sr investigated by safe Coulomb excitation of radioactive beams at the REX-ISOLDE facility, CERN. Reduced transition probabilities and spectroscopic quadrupole moments have been extracted from the differential Coulomb excitation cross section supporting the scenario of shape coexistence/change at N=60. Future perspectives are presented including the recent experimental campaign performed at ILL-Grenoble.

Dos visiones del 98: 1948/1998

Directory of Open Access Journals (Sweden)

García-Velasco, José

1998-06-01

Full Text Available Not available.Este artículo tiene un triple objeto: 1. Analizar, desde la perspectiva de la historia intelectual, el número extraordinario de Arbor (núm. 36, diciembre 1948 conmemorativo del cincuenta aniversario de 1898. 2. Valorar los cambios que se han producido, cincuenta años después, en nuestra perspectiva y conocimiento del «espíritu del 98». 3. Proponer algunas tareas prioritarias para la historia intelectual del periodo, a partir de la experiencia del trabajo realizado estos últimos años en la Residencia de Estudiantes. El número 36 de Arbor reunió a un grupo de escritores bajo el liderazgo de Pedro Laín Entralgo: M. Fernández Almagro (historia, J. M.ª García Escudero (íd., Gerardo Diego (poesía, Lafuente Ferrari (pintura, F. Sopeña (música, G. Bleiberg (revistas literarias, A. Gallego Morell (Ganivet, J. L. López Aranguren (Unamuno, G. Torrente Ballester (Hispanoamérica, H. Juretschke (crítica, J. L. Pinillos (bibliografía de Unamuno, J. M.ª Valverde (bibliografía de A. Machado, etc. En los apartados 2 y 3 del artículo se insiste especialmente en la necesidad de recurrir a las fuentes primarias y estudiar los fenómenos culturales en su contexto europeo. Se abordan los problemas existentes y las propuestas de trabajo en relación con las colecciones documentales, los planes de obras completas, las ediciones críticas, epistolarios, memorias, bibliografías, y los proyectos de seminarios y cursos pendientes.

Cine-oeso-gastro-scintigraphy (COGS) and gastro-oesophageal reflux (GOR): a 15-year experience; Cine-oesogastroscintigraphie et reflux gastro-oesophagien de l`enfant: 15 ans d`experience

Energy Technology Data Exchange (ETDEWEB)

Guillet, J.; Role, C.; Joussein, M.

1996-12-31

Eight thousand COGS were performed, searching for, quantifying and visualizing GOR, and possibly associated oesophageal dismotility or gastric emptying disorders in neonates (15 %), infants (33 %), children 1-4 (20%), 4-8 (20%) and 8-16 years old (14%). Indications were medical or surgical, to diagnoses, assess or follow up GOR with or without treatment. GOR was discovered in 65 % of the cases. A respiratory contamination by GOR aspiration was visualized in 4 % of patients with recurrent respiratory diseases, or near miss from sudden infant death syndrome (SIDS). Pathological patterns of gastric emptying in SIDS are emphasized. Oesophageal motility dysfunctions, primary or related to oesophagitis, are visualized and quantified by scintigraphic imaging. PH-metry and scintigraphy accuracies and their relative positions are discussed. (authors). 117 refs., 8 figs., 5 tabs.

Theater Security Cooperation Planning with Article 98: How the 2002 Servicemembers' Protection Act Fosters China's Quest for Global Influence

National Research Council Canada - National Science Library

Hernandez, Jaime A

2005-01-01

.... Designed to remedy these restrictions, nonsurrender bilateral Article 98 agreements are fostering resentment of American global hegemony which China is leveraging to expand her influence worldwide...

X-ray photoelectron spectroscopy investigations of band offsets in Ga0.02Zn0.98O/ZnO heterojunction for UV photodetectors

Science.gov (United States)

Singh, Karmvir; Rawal, Ishpal; Punia, Rajesh; Dhar, Rakesh

2017-10-01

Here, we report the valence and conduction band offset measurements in pure ZnO and the Ga0.02Zn0.98O/ZnO heterojunction by X-Ray photoelectron spectroscopy studies for UV photodetector applications. For detailed investigations on the band offsets and UV photodetection behavior of Ga0.02Zn0.98O/ZnO heterostructures, thin films of pristine ZnO, Ga-doped ZnO (Ga0.02Zn0.98O), and heterostructures of Ga-doped ZnO with ZnO (Ga0.02Zn0.98O/ZnO) were deposited using a pulsed laser deposition technique. The deposited thin films were characterized by X-ray diffraction, atomic force microscopy, and UV-Vis spectroscopy. X-ray photoelectron spectroscopy studies were carried out on all the thin films for the investigation of valence and conduction band offsets. The valence band was found to be shifted by 0.28 eV, while the conduction band has a shifting of -0.272 eV in the Ga0.02Zn0.98O/ZnO heterojunction as compared to pristine ZnO thin films. All the three samples were analyzed for photoconduction behavior under UVA light of the intensity of 3.3 mW/cm2, and it was observed that the photoresponse of pristine ZnO (19.75%) was found to increase with 2 wt. % doping of Ga (22.62%) and heterostructured thin films (29.10%). The mechanism of UV photodetection in the deposited samples has been discussed in detail, and the interaction of chemisorbed oxygen on the ZnO surface with holes generated by UV light exposure has been the observed mechanism for the change in electrical conductivity responsible for UV photoresponse on the present deposited ZnO films.

Expedited technology demonstration project (Revised mixed waste management facility project) Project baseline revision 4.0 and FY98 plan

International Nuclear Information System (INIS)

Adamson, M. G.

1997-01-01

The re-baseline of the Expedited Technology Demonstration Project (Revised Mixed Waste Facility Project) is designated as Project Baseline Revision 4.0. The last approved baseline was identified as Project Baseline Revision 3.0 and was issued in October 1996. Project Baseline Revision 4.0 does not depart from the formal DOE guidance followed by, and contained in, Revision 3.0. This revised baseline document describes the MSO and Final Forms testing activities that will occur during FY98, the final year of the ETD Project. The cost estimate for work during FY98 continues to be $2.OM as published in Revision 3.0. However, the funds will be all CENRTC rather than the OPEX/CENTRC split previously anticipated. LLNL has waived overhead charges on ETD Project CENRTC funds since the beginning of project activities. By requesting the $2.OM as all CENTRC a more aggressive approach to staffing and testing can be taken. Due to a cost under- run condition during FY97 procurements were made and work was accomplished, with the knowledge of DOE, in the Feed Preparation and Final Forms areas that were not in the scope of Revision 3.0. Feed preparation activities for FY98 have been expanded to include the drum opening station/enclosure previously deleted

Résultats de recherche | Page 98 | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

Infodivertissement vidéo : incidence sur les résultats en matière de santé des mères et des jeunes enfants à Toro, au Nigéria (IMCHA). Aux prises avec l'un des taux de mortalité maternelle parmi les plus élevés au monde, le Nigéria a déterminé que la santé des mères et des enfants est un enjeu prioritaire. Projet.

Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila.

Science.gov (United States)

Baril, Caroline; Gavory, Gwenaëlle; Bidla, Gawa; Knævelsrud, Helene; Sauvageau, Guy; Therrien, Marc

2017-01-01

Acute myeloid leukemia (AML) is a complex malignancy with poor prognosis. Several genetic lesions can lead to the disease. One of these corresponds to the NUP98-HOXA9 (NA9) translocation that fuses sequences encoding the N-terminal part of NUP98 to those encoding the DNA-binding domain of HOXA9. Despite several studies, the mechanism underlying NA9 ability to induce leukemia is still unclear. To bridge this gap, we sought to functionally dissect NA9 activity using Drosophila. For this, we generated transgenic NA9 fly lines and expressed the oncoprotein during larval hematopoiesis. This markedly enhanced cell proliferation and tissue growth, but did not alter cell fate specification. Moreover, reminiscent to NA9 activity in mammals, strong cooperation was observed between NA9 and the MEIS homolog HTH. Genetic characterization of NA9-induced phenotypes suggested interference with PVR (Flt1-4 RTK homolog) signaling, which is similar to functional interactions observed in mammals between Flt3 and HOXA9 in leukemia. Finally, NA9 expression was also found to induce non-cell autonomous effects, raising the possibility that its leukemia-inducing activity also relies on this property. Together, our work suggests that NA9 ability to induce blood cell expansion is evolutionarily conserved. The amenability of NA9 activity to a genetically-tractable system should facilitate unraveling its molecular underpinnings. Copyright © 2016 Elsevier Inc. All rights reserved.

Incidence, prevalence, and mortality of insulin-dependent (type 1) diabetes mellitus in Lithuanian children during 1983-98

DEFF Research Database (Denmark)

Urbonaite, Brone; Zalinkevicius, Rimas; Green, Anders

2002-01-01

AIMS/HYPOTHESIS: Our purpose is to analyze interrelations of the incidence, prevalence and mortality of childhood-onset insulin-dependent diabetes mellitus (type 1) in Lithuania. METHODS: Incidence and prevalence rates were based on the national type 1 diabetes register during 1983-98. The cohort...

Towards Superheavies: Spectroscopy of 94 < Z < 98, 150 < N < 154 Nuclei

Directory of Open Access Journals (Sweden)

Chowdhury P.

2016-01-01

nuclear structure studies are important testing grounds for theoretical models that aim to describe superheavy nuclei. To study the highest neutron orbitals (150 ≤ N ≤ 154, we have populated high angular momentum states in a series of Pu (Z = 94, Cm (Z = 96 and Cf (Z = 98 nuclei, via inelastic and transfer reactions, with heavy beams on long-lived radioactive actinide targets. Multiple collective excitation modes and structures were identified, and their configurations deduced. Quasiparticle alignments are mapped, with odd-A band structures helping identify specific orbital contributions via blocking arguments. Higher-order multipole shapes are observed to play a significant role in disentangling competing neutron and proton alignments. The N > 152 data provide new perspectives on physics beyond the N = 152 sub-shell gap.

Phase, microstructure and microwave dielectric properties of Mg0:95Ni0:05Ti0:98Zr0:02O3 ceramics

Directory of Open Access Journals (Sweden)

Manan Abdul

2015-03-01

Full Text Available Mg0:95Ni0:05Ti0:98Zr0:02O3 ceramics was prepared via conventional solid-state mixed-oxide route. The phase, microstructure and microwave dielectric properties of the sintered samples were characterized using X-ray diffraction (XRD, scanning electron microscopy (SEM and a vector network analyzer. The microstructure comprised of circular and elongated plate-like grains. The semi quantitative analysis (EDS of the circular and elongated grains revealed the existence of Mg0:95Ni0:05T2O5 as a secondary phase along with the parent Mg0:95Ni0:05Ti0:98Zr0:02O3 phase, which was consistent with the XRD findings. In the present study, εr ~17.1, Qufo~195855 ± 2550 GHz and τf ~ -46 ppm/K was achieved for the synthesized Mg0:95Ni0:05Ti0:98Zr0:02O3 ceramics sintered at 1325 °C for 4 h.

The Swedish Nuclear Power Inspectorate's evaluation of SKB's RD and D Program 98. Summary and conclusions

International Nuclear Information System (INIS)

1999-04-01

Compared to previous programmes, RD and D Programme 98 is focused to a greater extent on method and site selection and on issues relating to the decision-making process. This is natural, since the programme is now approaching the stage where vital decisions will have to be made. The RD and D Programme 98 report is supplemented by a background report 'Detailed Programme for Research and Development 1999-2004' as well as a number of main references 'System Reporting', 'Alternative methods', 'Criteria for Site Evaluation' and the 'North-South/Coast-Interior' report. In addition, a number of references are available in the form of county-specific general siting studies, feasibility studies etc. SKI has distributed RD and D Programme 98 to sixty-three reviewing bodies for comment. The reviewing bodies include universities and institutes of technology, local safety committees, municipalities hosting nuclear facilities and municipalities participating in feasibility studies as well as many authorities. The comments of the reviewing bodies mainly focused on the decision-making process, including issues relating to method selection and site selection and, in particular, on the selection of sites for site investigation. Several reviewing bodies, particularly universities and institutes of technology, have also submitted comments of a more technical-scientific nature. SKI's evaluation has focused on determining whether SKB's programme can be considered to fulfil the requirements stipulated in the Act on Nuclear Activities that such a programme should be able to result in the implementation of solutions for the final disposal of the spent nuclear fuel from the Swedish nuclear power programme. Furthermore, SKI's evaluation has also focused on the conditions that SKI considers should apply to SKB's future work. Specific comments are made for the following areas: Decision-making process, Method selection and system analysis, Siting, Technical development, Safety assessments

The Authenticity of the Document at Andocides On the Mysteries 95-98

Directory of Open Access Journals (Sweden)

Edward Monroe Harris

2015-10-01

Full Text Available This essays studies the document inserted into the text of Andocides' speech On the Mysteries (96-98 and shows that it is not a genuine copy of the decree of Demophantus from an analysis of its contents and a comparison with the formulas and language of decrees from the late fifth and fourth centuries BCE preserved on stone. The final part of the essay analyzes the historical context of the decree of Demophantus and shows that it belongs in the period where Lycurgus (Against Leocrates 124-127 places it, that is, after the overthrow of the Thirty in 403 BCE.

Theoretical physics department, june 96-may 98 status report

International Nuclear Information System (INIS)

1998-01-01

This status report presents the work done at SPhT (service de physique theorique, CEA) from june 96 to may 98. The topics have been classified into 3 themes: - statistical physics, - mathematical physics and field theory, - astrophysics, nuclear and particle physics. In the first theme relevant contributions have been made to phase transitions, correlated electronic systems, polymers, membranes, proteins, disordered systems and out of equilibrium processes. The second theme collects various works, some works dedicated to aleatory matrices and quantum chaos aim at developing investigation methods, other works like cord theories use these methods. As for the third theme, the recent discovery of the fluctuations of background cosmological radiation has fomented a great activity at SPhT. Mean field approximation and effective strength have been the starting point of research in the field of nuclear structure. High energy quantum chromodynamics has been applied to deep inelastic scattering where the proton structure is studied through electron-proton collisions. A list of all the publications made by SPhT is given. (A.C.)

Symptom profile as assessed on delirium rating scale-revised-98 of delirium in respiratory intensive care unit: A study from India

Directory of Open Access Journals (Sweden)

Akhilesh Sharma

2017-01-01

Full Text Available Aim: This study aimed to evaluate the phenomenology of delirium in patients admitted in a Respiratory Intensive Care Unit (RICU. Methods: Consecutive patients admitted to RICU were screened for delirium using Richmond Agitation-Sedation Scale (RASS, Confusion Assessment Method for ICU (CAM-ICU assessment tool and those found positive for delirium were evaluated by a psychiatrist to confirm the diagnosis. Those with a diagnosis of delirium as per the psychiatrist were evaluated on Delirium Rating Scale-Revised-98 (DRS-R-98 to study phenomenology. Results: All the 75 patients fulfilled the criteria of “acute onset of symptoms” and “presence of an underlying physical disorder” as per the DRS-R-98. Commonly seen symptoms of delirium included disturbances in attention (100%, thought process abnormality (100%, fluctuation in symptoms (97.33% disturbance in, sleep-wake cycle, language disturbance (94.7%, disorientation (81.33%, and short-term memory impairments (73.33%. No patient had delusions and very few (5.3% reported perceptual disturbances. According to RASS subtyping, hypoactive delirium was the most common subtype (n = 34; 45.33%, followed by hyperactive subtype (n = 28; 37.33% and a few patients had mixed subtype of delirium (n = 13; 17.33%. Factor structure of DRS-R-98 symptoms yielded 3 factors (Factor-1: cognitive factor; Factor-2: motoric factor; Factor-3; thought, language, and fluctuation factor. Conclusion: The phenomenology of delirium in ICU patients is similar to non-ICU patients, but hypoactive delirium is the most common subtype.

Recent results on Pb+Pb collisions at 158 AGeV from the WA98 experiment at CERN

NARCIS (Netherlands)

Wyslouch, B

1998-01-01

We present recent results obtained with the WA98 experiment at CERN SPS. The experiment consists of large acceptance hadron and photon spectrometers which allow to study many aspects of heavy ion collisions. We use event-by-event measurements of charged and neutral particle multiplicity to establish

Biochemical, transcriptional and translational evidences of the phenol-meta-degradation pathway by the hyperthermophilic Sulfolobus solfataricus 98/2.

Directory of Open Access Journals (Sweden)

Alexia Comte

Full Text Available Phenol is a widespread pollutant and a model molecule to study the biodegradation of monoaromatic compounds. After a first oxidation step leading to catechol in mesophilic and thermophilic microorganisms, two main routes have been identified depending on the cleavage of the aromatic ring: ortho involving a catechol 1,2 dioxygenase (C12D and meta involving a catechol 2,3 dioxygenase (C23D. Our work aimed at elucidating the phenol-degradation pathway in the hyperthermophilic archaea Sulfolobus solfataricus 98/2. For this purpose, the strain was cultivated in a fermentor under different substrate and oxygenation conditions. Indeed, reducing dissolved-oxygen concentration allowed slowing down phenol catabolism (specific growth and phenol-consumption rates dropped 55% and 39%, respectively and thus, evidencing intermediate accumulations in the broth. HPLC/Diode Array Detector and LC-MS analyses on culture samples at low dissolved-oxygen concentration (DOC  =  0.06 mg x L(-1 suggested, apart for catechol, the presence of 2-hydroxymuconic acid, 4-oxalocrotonate and 4-hydroxy-2-oxovalerate, three intermediates of the meta route. RT-PCR analysis on oxygenase-coding genes of S. solfataricus 98/2 showed that the gene coding for the C23D was expressed only on phenol. In 2D-DIGE/MALDI-TOF analysis, the C23D was found and identified only on phenol. This set of results allowed us concluding that S. solfataricus 98/2 degrade phenol through the meta route.

Preparation of 90Sr-90Y generator

International Nuclear Information System (INIS)

Jin Xiaohai; Yu Haibin; Zhang Jinming; Zhang Peixin; Lin Qiongfang

1990-01-01

In recent years, 90 Y has been considered as one of the best radionuclides for tumor radioimmunotherapy when chelated to tumor-associated antibodies. This evaluation is based on the superior properties of this radionuclide (suitable half-life, pure β-ray emitter of intermediate energy, stable daughters, and suitable chemical properties) and because it is available as a radionuclide generator product by decay of its 28a parent 90 Sr. The experimental conditions of 90 Sr- 90 Y generator are described. The elution efficiency of 90 Sr- 90 Y generator reaches 98%. One of the most important problems is the 90 Sr contamination breakthrough from the generator. The level of 90 Sr contamination must be controlled to the clinical standard. The cation exchange resin 732 (100-150 mesh) was successfully used for the separation of 90 Y from 90 Sr. The method used by the authors provides a 90 Y-HAc solution which is very simple and safe for administration to the patients. 90 Y was separated from 90 Sr almost completely, the level of the 90 Sr contamination per 740 MBq 90 Y product was only 0.74 kBq. However the toxicity of 90 Sr is extremely high, the human life-time permissible dose is 74 kBq, then 740 MBq of 90 Y is allowed to be administrated to a patient for 50-100 times

TEWS'98. Final report [5th annual International Science Camp: The Earth We Share 1998, Golden, CO

Energy Technology Data Exchange (ETDEWEB)

Mae C. Jemison

1999-04-06

The fifth annual International Science Camp The Earth We Share 1998 (TEWS'98) was held at the Colorado School of Mines located in Goldez Colorado. TEWS98 was a four week residential program which focused on providing a meaningful science education experience while developing critical thinking skills. Thirty three students, three teachers, four college interns and the camp administrator lived and worked together while developing solutions to several worldwide problems. These problems are called the Discovery Topics and they are: (1) design the worlds perfect house; (2) how many people can the world hold; and (3) predict the hot stocks for the year 2030. The participants, both students and staff came from different countries all over the world The following countries were represented: The United Kingdom, Sierra Leone (West Africa), Ireland, USA Nigeria, West Indies and Barbados.

Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: the BIG 1-98 trial

DEFF Research Database (Denmark)

Crivellari, D.; Sun, Z.; Coates, A.S.

2008-01-01

PURPOSE: To explore potential differences in efficacy, treatment completion, and adverse events (AEs) in elderly women receiving adjuvant tamoxifen or letrozole for five years in the Breast International Group (BIG) 1-98 trial. METHODS: This report includes the 4,922 patients allocated to 5 years...... of letrozole or tamoxifen in the BIG 1-98 trial. The median follow-up was 40.4 months. Subpopulation Treatment Effect Pattern Plot (STEPP) analysis was used to examine the patterns of differences in disease-free survival and incidences of AEs according to age. In addition, three categoric age groups were...... had superior efficacy (DFS) compared with tamoxifen in all age groups. On the basis of a small number of patients older than 75 years (6%), age per se should not unduly affect the choice of adjuvant endocrine therapy Udgivelsesdato: 2008/4/20...

1: Mass asymmetric fission barriers for 98Mo; 2: Synthesis and characterization of actinide-specific chelating

International Nuclear Information System (INIS)

Veeck, A.C.; Lawrence Livermore National Lab., CA; Lawrence Berkeley National Lab., CA

1996-08-01

Excitation functions have been measured for complex fragment emission from the compound nucleus 98 Mo, produced by the reaction of 86 Kr with 12 C. Mass asymmetric fission barriers have been obtained by fitting the excitation functions with a transition state formalism. The extracted barriers are ∼ 5.7 MeV higher, on average, than the calculations of the Rotating Finite Range Model (RFRM). These data clearly show an isospin dependence of the conditional barriers when compared with the extracted barriers from 90 Mo and 94 Mo. Eleven different liquid/liquid extractants were synthesized based upon the chelating moieties 3,2-HOPO and 3,4-HOPO; additionally, two liquid/liquid extractants based upon the 1,2-HOPO chelating moiety were obtained for extraction studies. The Pu(IV) extractions, quite surprisingly, yielded results that were very different from the Fe(III) extractions. The first trend remained the same: the 1,2-HOPOs were the best extractants, followed closely by the 3,2-HOPOs, followed by the 3,4-HOPOs; but in these Pu(IV) extractions the 3,4-HOPOs performed much better than in the Fe(III) extractions. 129 refs

Magnetic properties of the compound Zn(Mnsub(0.98)Fesub(0.02)2O4

International Nuclear Information System (INIS)

Wautelet, M.; Gerard, A.

1975-01-01

Moessbauer spectra were measured of the compound Zn(Mnsub(0.98)Fesub(0.02)) 2 O 4 at several temperatures between 4.2 and 77 K. Evaluation of the spectra showed that the Neel temperature of ZnMn 2 O 4 does not exceed 50 K; the magnetic structure seems to be the same as that of Mn 3 O 4 with predominant B-B interactions. (A.K.)

The 1997-98 financial crisis in Malaysia: causes, response, and results – A Rejoinder

OpenAIRE

Hasan, Zubair

2003-01-01

This rejoinder refutes the comments of Mohamed Ariff and Faiz Mohammad on the author’s article: The 1997-98 Financial Crisis in Malaysia: Causes, Response, and Results”, published in the Islamic Economic Studies, Vol. 9 No. 2, 2002. My basic difference with the reviewers is this: they maintain that weaknesses of the sort piling up in the economy over the years invited currency attack, while I have reasons to believe that it came to Malaysia independently of her fundamental, rather eroded them...

A comparison of outcomes according to different diagnostic systems for delirium (DSM-5, DSM-IV, CAM, and DRS-R98).

Science.gov (United States)

Adamis, Dimitrios; Meagher, David; Rooney, Siobhan; Mulligan, Owen; McCarthy, Geraldine

2018-04-01

ABSTRACTStudies indicate that DSM-5 criteria for delirium are relatively restrictive, and identify different cases of delirium compared with previous systems. We evaluate four outcomes of delirium (mortality, length of hospital stay, institutionalization, and cognitive improvement) in relation to delirium defined by different DSM classification systems.Prospective, longitudinal study of patients aged 70+ admitted to medical wards of a general hospital. Participants were assessed up to a maximum of four times during two weeks, using DSM-5 and DSM-IV criteria, DRS-R98 and CAM scales as proxies for DSM III-R and DSM III.Of the 200 assessed patients (mean age 81.1, SD = 6.5; and 50% female) during hospitalization, delirium was identified in 41 (20.5%) using DSM-5, 45 (22.5%) according to DSM-IV, 46 (23%) with CAM positive, and 37 (18.5%) with DRS-R98 severity score >15. Mortality was significantly associated with delirium according to any classification system, but those identified with DSM-5 were at greater risk. Length of stay was significantly longer for those with DSM-IV delirium. Discharge to a care home was associated only with DRS-R98 defined delirium. Cognitive improvement was only associated with CAM and DSM-IV. Different classification systems for delirium identify populations with different outcomes.

Travel-related acquisition of diarrhoeagenic bacteria, enteral viruses and parasites in a prospective cohort of 98 Dutch travellers

NARCIS (Netherlands)

van Hattem, Jarne M.; Arcilla, Maris S.; Grobusch, Martin Peter; Bart, Aldert; Bootsma, Martin C; van Genderen, Perry J J; van Gool, Tom; Goorhuis, Abraham; van Hellemond, Jaap J.; Molenkamp, Richard; Molhoek, Nicky; Oude Lashof, Astrid M L; Stobberingh, Ellen E; de Wever, Bob; Verbrugh, Henri A; Melles, Damian C.; Penders, John; Schultsz, Constance; de Jong, Menno D

BACKGROUND: Limited prospective data are available on the acquisition of viral, bacterial and parasitic diarrhoeagenic agents by healthy individuals during travel. METHODS: To determine the frequency of travel associated acquisition of 19 pathogens in 98 intercontinental travellers, qPCR was used to

Travel-related acquisition of diarrhoeagenic bacteria, enteral viruses and parasites in a prospective cohort of 98 Dutch travellers

NARCIS (Netherlands)

van Hattem, Jarne M; Arcilla, Maris S; Grobusch, Martin P; Bart, Aldert; Bootsma, Martin C.; van Genderen, Perry J J; van Gool, Tom; Goorhuis, Abraham; van Hellemond, Jaap J.; Molenkamp, Richard; Molhoek, Nicky; Oude Lashof, Astrid Ml; Stobberingh, Ellen E; de Wever, Bob; Verbrugh, Henri A; Melles, Damian C; Penders, John; Schultsz, Constance; de Jong, Menno D.

2017-01-01

Background Limited prospective data are available on the acquisition of viral, bacterial and parasitic diarrhoeagenic agents by healthy individuals during travel. Methods To determine the frequency of travel associated acquisition of 19 pathogens in 98 intercontinental travellers, qPCR was used to

Travel-related acquisition of diarrhoeagenic bacteria, enteral viruses and parasites in a prospective cohort of 98 Dutch travellers

NARCIS (Netherlands)

van Hattem, Jarne M.; Arcilla, Maris S.; Grobusch, Martin P.; Bart, Aldert; Bootsma, Martin C.; van Genderen, Perry J.; van Gool, Tom; Goorhuis, Abraham; van Hellemond, Jaap J.; Molenkamp, Richard; Molhoek, Nicky; Oude Lashof, Astrid M.; Stobberingh, Ellen E.; de Wever, Bob; Verbrugh, Henri A.; Melles, Damian C.; Penders, John; Schultsz, Constance; de Jong, Menno D.

2017-01-01

Background: Limited prospective data are available on the acquisition of viral, bacterial and parasitic diarrhoeagenic agents by healthy individuals during travel. Methods: To determine the frequency of travel associated acquisition of 19 pathogens in 98 intercontinental travellers, qPCR was used to

Loss Modelling and Experimental Verification of A 98.8% Efficiency Bidirectional Isolated DC-DC Converter

Directory of Open Access Journals (Sweden)

Ramachandran Rakesh

2017-01-01

In this paper, design and implementation of an ultra-high efficiency isolated bi-directional dc-dc converter utilizing GaN devices is presented. Loss modelling of the GaN converter is also included in this paper. The converter has achieved a maximum measured efficiency of 98.8% in both directions of power flow, using the same power components. Hardware prototype of the converter along with the measured efficiency curve is also presented in this paper.

NASA Occupational Health Program FY98 Self-Assessment

Science.gov (United States)

Brisbin, Steven G.

1999-01-01

The NASA Functional Management Review process requires that each NASA Center conduct self-assessments of each functional area. Self-Assessments were completed in June 1998 and results were presented during this conference session. During FY 97 NASA Occupational Health Assessment Team activities, a decision was made to refine the NASA Self-Assessment Process. NASA Centers were involved in the ISO registration process at that time and wanted to use the management systems approach to evaluate their occupational health programs. This approach appeared to be more consistent with NASA's management philosophy and would likely confer status needed by Senior Agency Management for the program. During FY 98 the Agency Occupational Health Program Office developed a revised self-assessment methodology based on the Occupational Health and Safety Management System developed by the American Industrial Hygiene Association. This process was distributed to NASA Centers in March 1998 and completed in June 1998. The Center Self Assessment data will provide an essential baseline on the status of OHP management processes at NASA Centers. That baseline will be presented to Enterprise Associate Administrators and DASHO on September 22, 1998 and used as a basis for discussion during FY 99 visits to NASA Centers. The process surfaced several key management system elements warranting further support from the Lead Center. Input and feedback from NASA Centers will be essential to defining and refining future self assessment efforts.

USO DO ENXERTO ÓSSEO CORTICAL BOVINO CONSERVADO EM GLICERINA A 98% NA OSTEOTOMIA FEMORAL EM GATOS USE BOVINE CORTICAL BONE, PRESERVED IN 98% GLICERIN IN FEMORAL OSTEOTOMY IN CATS.

Directory of Open Access Journals (Sweden)

Lucia Helena de Carvalho Penha

2008-12-01

Full Text Available Enxerto cortical bovino, sob a forma de pino com 4mm de largura e 10cm de comprimento, conservado em glicerina a 98% por trinta dias no mínimo, foi implantado no canal medular de dez gatos e utilizado como único método de fixação, após osteotomia transversa da diáfise femoral esquerda, com o objetivo de avaliar clínica e radiograficamente a eficácia dos xenoenxertos como substitutos aos pinos de metal. Distribuíram-se os animais em dois grupos de cinco gatos, um com gatos jovens com idade inferior a um ano e um grupo de cinco gatos adultos com mais de um ano de idade. Em média, a deambulação normal ocorreu aos quinze dias, com união óssea radiográfica em 16,6 semanas. Dentre os cinco animais do grupo jovem, dois sofreram fratura do enxerto com desvio grave de eixo ósseo, mas sem fratura das corticais femorais e nos três animais restantes o processo de remodelação foi notado em tempo médio de 75 dias. Dos cinco animais do grupo adulto, todos sofreram acavalamento de vários graus, sendo considerado grave em dois animais, por estar associado com fratura das respectivas corticais femorais, mas sem desvio de eixo ósseo. Dos demais animais com acavalamento de grau leve, um apresentou união retardada, um apresentou fratura do enxerto e um apresentou calo ósseo não exuberante, encontrando-se em remodelação aos 110 dias. Pode-se concluir que o método de implantação intramedular de pino ósseo cortical bovino, preservado em glicerina a 98% em gatos jovens e adultos, foi adequadamente empregado, proporcionando suporte mecânico em tempo suficiente para união óssea.

PALAVRAS-CHAVES: Enxerto cortical bovino, fêmur, fratura, gatos, osteotomia. Cortical xenografts derived from bovine boné and shaped as intramedullary nails, with 4mm of width and 10cm or lenght, preserved in 98% glycerol for a minimum of 30 days were used as the sole method of internal fixation for transverse osteotomy of feline femoral diaphysis

Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue

International Nuclear Information System (INIS)

Antonov, Janine; Altermatt, Hans Jörg; Aebi, Stefan; Jaggi, Rolf; Popovici, Vlad; Delorenzi, Mauro; Wirapati, Pratyaksha; Baltzer, Anna; Oberli, Andrea; Thürlimann, Beat; Giobbie-Hurder, Anita; Viale, Giuseppe

2010-01-01

The purpose of the work reported here is to test reliable molecular profiles using routinely processed formalin-fixed paraffin-embedded (FFPE) tissues from participants of the clinical trial BIG 1-98 with a median follow-up of 60 months. RNA from fresh frozen (FF) and FFPE tumor samples of 82 patients were used for quality control, and independent FFPE tissues of 342 postmenopausal participants of BIG 1-98 with ER-positive cancer were analyzed by measuring prospectively selected genes and computing scores representing the functions of the estrogen receptor (eight genes, ER-8), the progesterone receptor (five genes, PGR-5), Her2 (two genes, HER2-2), and proliferation (ten genes, PRO-10) by quantitative reverse transcription PCR (qRT-PCR) on TaqMan Low Density Arrays. Molecular scores were computed for each category and ER-8, PGR-5, HER2-2, and PRO-10 scores were combined into a RISK-25 score. Pearson correlation coefficients between FF- and FFPE-derived scores were at least 0.94 and high concordance was observed between molecular scores and immunohistochemical data. The HER2-2, PGR-5, PRO-10 and RISK-25 scores were significant predictors of disease free-survival (DFS) in univariate Cox proportional hazard regression. PRO-10 and RISK-25 scores predicted DFS in patients with histological grade II breast cancer and in lymph node positive disease. The PRO-10 and PGR-5 scores were independent predictors of DFS in multivariate Cox regression models incorporating clinical risk indicators; PRO-10 outperformed Ki-67 labeling index in multivariate Cox proportional hazard analyses. Scores representing the endocrine responsiveness and proliferation status of breast cancers were developed from gene expression analyses based on RNA derived from FFPE tissues. The validation of the molecular scores with tumor samples of participants of the BIG 1-98 trial demonstrates that such scores can serve as independent prognostic factors to estimate disease free survival (DFS) in

Estimation of nitrate flux in a tidal front satellite-derived temperature data

Digital Repository Service at National Institute of Oceanography (India)

Morin, P; Wafar, M.V.M.; Corre, P

stream_size 7 stream_content_type text/plain stream_name J_Geophys_Res_C_98_4689.pdf.txt stream_source_info J_Geophys_Res_C_98_4689.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells

International Nuclear Information System (INIS)

Hou, Y.; Chu, M.; Du, F.F.; Lei, J.Y.; Chen, Y.; Zhu, R.Y.; Gong, X.H.; Ma, X.; Jin, J.

2013-01-01

Highlights: •rhddADAM15 inhibited the proliferation and migration of Bel-7402 cells. •rhddADAM15 inhibited growth and metastasis of Bel-7402 cells in zebrafish xenograft. •rhddADAM15 induced apoptosis in Bel-7402 cells and somatic cells of zebrafish. •Cell-cycle in Bel-7402 cells showed a partial G 2 /S arrest. •Activity of caspases 8, 9 and 3 was increased in rhddADAM15-treated Bel-7402 cells. -- Abstract: ADAM15 (A Disintegrin And Metalloproteinase 15), a transmembrane protein containing seven domains, interacts with some integrins via its disintegrin domain and overexpresses in many solid tumors. In this study, the effect of the recombinant human disintegrin domain (rhddADAM15) on the proliferation and migration of Bel-7402 cells was evaluated in vitro and in vivo in zebrafish xenografts. rhddADAM15 (4 μM) severely inhibited the proliferation and migration of Bel-7402 cells, inducing a partial G 2 /S arrest and morphological nucleus changes of apoptosis. Moreover, the activity of caspases 8, 9 and 3 in Bel-7402 cells was increased. In addition, the zebrafish was used as a model for apoptosis-induction and tumor-xenograft. rhddADAM15 (1 pM) inhibited the growth and metastasis of Bel-7402 cell xenografts in zebrafish and a lower concentration (0.1 pM) induced severe apoptosis in the somatic cells of zebrafish. In conclusion, our data identified rhddADAM15 as a potent inhibitor of tumor growth and metastasis, making it a promising tool for use in anticancer treatment

Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells

Energy Technology Data Exchange (ETDEWEB)

Hou, Y. [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China); Chu, M. [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Medicine, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China); Du, F.F.; Lei, J.Y.; Chen, Y.; Zhu, R.Y.; Gong, X.H.; Ma, X. [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China); Jin, J., E-mail: jinjian31@126.com [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China)

2013-06-14

Highlights: •rhddADAM15 inhibited the proliferation and migration of Bel-7402 cells. •rhddADAM15 inhibited growth and metastasis of Bel-7402 cells in zebrafish xenograft. •rhddADAM15 induced apoptosis in Bel-7402 cells and somatic cells of zebrafish. •Cell-cycle in Bel-7402 cells showed a partial G{sub 2}/S arrest. •Activity of caspases 8, 9 and 3 was increased in rhddADAM15-treated Bel-7402 cells. -- Abstract: ADAM15 (A Disintegrin And Metalloproteinase 15), a transmembrane protein containing seven domains, interacts with some integrins via its disintegrin domain and overexpresses in many solid tumors. In this study, the effect of the recombinant human disintegrin domain (rhddADAM15) on the proliferation and migration of Bel-7402 cells was evaluated in vitro and in vivo in zebrafish xenografts. rhddADAM15 (4 μM) severely inhibited the proliferation and migration of Bel-7402 cells, inducing a partial G{sub 2}/S arrest and morphological nucleus changes of apoptosis. Moreover, the activity of caspases 8, 9 and 3 in Bel-7402 cells was increased. In addition, the zebrafish was used as a model for apoptosis-induction and tumor-xenograft. rhddADAM15 (1 pM) inhibited the growth and metastasis of Bel-7402 cell xenografts in zebrafish and a lower concentration (0.1 pM) induced severe apoptosis in the somatic cells of zebrafish. In conclusion, our data identified rhddADAM15 as a potent inhibitor of tumor growth and metastasis, making it a promising tool for use in anticancer treatment.

Global Impacts and Regional Actions: Preparing for the 1997-98 El Niño.

Science.gov (United States)

Buizer, James L.; Foster, Josh; Lund, David

2000-09-01

It has been estimated that severe El Niño-related flooding and droughts in Africa, Latin America, North America, and Southeast Asia resulted in more than 22 000 lives lost and in excess of $36 billion in damages during 1997-98. As one of the most severe events this century, the 1997-98 El Niño was unique not only in terms of physical magnitude, but also in terms of human response. This response was made possible by recent advances in climate-observing and forecasting systems, creation and dissemination of forecast information by institutions such as the International Research Institute for Climate Prediction and NOAA's Climate Prediction Center, and individuals in climate-sensitive sectors willing to act on forecast information by incorporating it into their decision-making. The supporting link between the forecasts and their practical application was a product of efforts by several national and international organizations, and a primary focus of the United States National Oceanic and Atmospheric Administration Office of Global Programs (NOAA/OGP).NOAA/OGP over the last decade has supported pilot projects in Latin America, the Caribbean, the South Pacific, Southeast Asia, and Africa to improve transfer of forecast information to climate sensitive sectors, study linkages between climate and human health, and distribute climate information products in certain areas. Working with domestic and international partners, NOAA/OGP helped organize a total of 11 Climate Outlook Fora around the world during the 1997-98 El Niño. At each Outlook Forum, climatologists and meteorologists created regional, consensus-based, seasonal precipitation forecasts and representatives from climate-sensitive sectors discussed options for applying forecast information. Additional ongoing activities during 1997-98 included research programs focused on the social and economic impacts of climate change and the regional manifestations of global-scale climate variations and their effect on

Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells

Energy Technology Data Exchange (ETDEWEB)

Le Vee, Marc; Jouan, Elodie; Lecureur, Valérie [Institut de Recherches en Santé, Environnement et Travail (IRSET), UMR INSERM U1085, Faculté de Pharmacie, 2 Avenue du Pr Léon Bernard, 35043 Rennes (France); Fardel, Olivier, E-mail: olivier.fardel@univ-rennes1.fr [Institut de Recherches en Santé, Environnement et Travail (IRSET), UMR INSERM U1085, Faculté de Pharmacie, 2 Avenue du Pr Léon Bernard, 35043 Rennes (France); Pôle Biologie, Centre Hospitalier Universitaire, 2 rue Henri Le Guilloux, 35033 Rennes (France)

2016-01-01

The heterodimeric L-type amino acid transporter (LAT) 1/CD98hc is overexpressed in lung cancers with a poor prognosis factor. Factors that contribute to LAT1/CD98hc overexpression in lung cells remain however to be determined, but the implication of atmospheric pollution can be suspected. The present study was therefore designed to analyze the effects of diesel exhaust particle (DEP) extract (DEPe) on LAT1/CD98hc expression in bronchial epithelial BEAS-2B cells. Exposure to DEPe up-regulated LAT1 and CD98hc mRNA levels in a concentration-dependent manner, with DEPe EC{sub 50} values (around 0.2 μg/mL) relevant to environmental situations. DEPe concomitantly induced LAT1/CD98hc protein expression and LAT1-mediated leucine accumulation in BEAS-2B cells. Inhibition of the aryl hydrocarbon receptor (AhR) pathway through the use of a chemical AhR antagonist or the siRNA-mediated silencing of AhR expression was next found to prevent DEPe-mediated induction of LAT1/CD98hc, indicating that this regulation depends on AhR, known to be activated by major chemical DEP components like polycyclic aromatic hydrocarbons. DEPe exposure was finally shown to induce mRNA expression and activity of matrix metalloproteinase (MMP)-2 in BEAS-2B cells, in a CD98hc/focal adhesion kinase (FAK)/extracellular regulated kinase (ERK) manner, thus suggesting that DEPe-mediated induction of CD98hc triggers activation of the integrin/FAK/ERK signaling pathway known to be involved in MMP-2 regulation. Taken together, these data demonstrate that exposure to DEPe induces functional overexpression of the amino acid transporter LAT1/CD98hc in lung cells. Such a regulation may participate to pulmonary carcinogenic effects of DEPs, owing to the well-documented contribution of LAT1 and CD98hc to cancer development. - Highlights: • The amino acid transporter LAT1/CD98hc is up-regulated in DEPe-treated lung cells. • The aryl hydrocarbon receptor is involved in DEPe-triggered induction of LAT1/CD98hc. �

miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions.

Science.gov (United States)

Rom, Slava; Dykstra, Holly; Zuluaga-Ramirez, Viviana; Reichenbach, Nancy L; Persidsky, Yuri

2015-12-01

Pathologic conditions in the central nervous system, regardless of the underlying injury mechanism, show a certain level of blood-brain barrier (BBB) impairment. Endothelial dysfunction is the earliest event in the initiation of vascular damage caused by inflammation due to stroke, atherosclerosis, trauma, or brain infections. Recently, microRNAs (miRNAs) have emerged as a class of gene expression regulators. The relationship between neuroinflammation and miRNA expression in brain endothelium remains unexplored. Previously, we showed the BBB-protective and anti-inflammatory effects of glycogen synthase kinase (GSK) 3β inhibition in brain endothelium in in vitro and in vivo models of neuroinflammation. Using microarray screening, we identified miRNAs induced in primary human brain microvascular endothelial cells after exposure to the pro-inflammatory cytokine, tumor necrosis factor-α, with/out GSK3β inhibition. Among the highly modified miRNAs, let-7 and miR-98 were predicted to target the inflammatory molecules, CCL2 and CCL5. Overexpression of let-7 and miR-98 in vitro and in vivo resulted in reduced leukocyte adhesion to and migration across endothelium, diminished expression of pro-inflammatory cytokines, and increased BBB tightness, attenuating barrier 'leakiness' in neuroinflammation conditions. For the first time, we showed that miRNAs could be used as a therapeutic tool to prevent the BBB dysfunction in neuroinflammation.

Adjuvant chemotherapy with sequential or concurrent anthracycline and docetaxel: Breast International Group 02-98 randomized trial

DEFF Research Database (Denmark)

Francis, P.; Crown, J.; Di, Leo A.

2008-01-01

BACKGROUND: Docetaxel is more effective than doxorubicin for patients with advanced breast cancer. The Breast International Group 02-98 randomized trial tested the effect of incorporating docetaxel into anthracycline-based adjuvant chemotherapy and compared sequential vs concurrent administration....... However, important differences may be related to doxorubicin and docetaxel scheduling, with sequential but not concurrent administration, appearing to produce better DFS than anthracycline-based chemotherapy Udgivelsesdato: 2008/1/16...

Quantitative calculation of GOR of complex oil-gas-water systems with logging data: A case study of the Yingdong Oil/Gas Field in the Qaidam Basin

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Sima Liqiang

2014-12-01

Full Text Available In the Yingdong Oil/Gas Field of the Qaidam Basin, multiple suites of oil-gas-water systems overlie each other vertically, making it difficult to accurately identify oil layers from gas layers and calculate gas-oil ratio (GOR. Therefore, formation testing and production data, together with conventional logging, NMR and mud logging data were integrated to quantitatively calculate GOR. To tell oil layers from gas layers, conventional logging makes use of the excavation effect of compensated neutron log, NMR makes use of the different relaxation mechanisms of light oil and natural gas in large pores, while mud logging makes use of star chart of gas components established based on available charts and mathematical statistics. In terms of the quantitative calculation of GOR, the area ratio of the star chart of gas components was first used in GOR calculation. The study shows that: (1 conventional logging data has a modest performance in distinguishing oil layers from gas layers due to the impacts of formation pressure, hydrogen index (HI, shale content, borehole conditions and invasion of drilling mud; (2 NMR is quite effective in telling oil layers from gas layers, but cannot be widely used due to its high cost; (3 by contrast, the star chart of gas components is the most effective in differentiating oil layers from gas layers; and (4 the GOR calculated by using the area ratio of star chart has been verified by various data such as formation testing data, production data and liquid production profile.

Task III: UCSD/DIII-D/Textor FY-97-98 Accomplishments

International Nuclear Information System (INIS)

Boedo, J.A.

2000-01-01

OAK (B204) Task III: UCSD/DIII-D/Textor FY-97-98 Accomplishments. A comprehensive report on the physics of pump limiters and particularly, the characterization of ALT-II, was published in Nuclear Fusion, bringing the project to a closure. The performance of the toroidal pump limiter was characterized under full auxiliary heating of 7 MW of NBI and ICRH and full pumping, as stated in the project milestones. Relevant highlights are: (1) Pumping with ALT-II allows for density control. (2) The achieved exhaust efficiency is 4% during NBI operation and near 2% during OH or ICRH operation. (3) We have shown that an exhaust efficiency of 2% is sufficient to satisfy the ash removal requirements of fusion reactors. (4) The plasma particle efflux and the pumped flux both increase with density and heating power. (5) The particle confinement time is less than the energy confinement time by a factor of 4. In summary, pumped belt limiters could provide the density control and ash exhaust requirements of fusion reactors

Let-7, mir-98 and mir-183 as biomarkers for cancer and schizophrenia [corrected].

Directory of Open Access Journals (Sweden)

Emmanouil Rizos

Full Text Available Recent evidence supports a role of microRNAs in cancer and psychiatric disorders such as schizophrenia and bipolar disorder, through their regulatory role on the expression of multiple genes. The rather rare co-morbidity of cancer and schizophrenia is an old hypothesis which needs further research on microRNAs as molecules that might exert their oncosuppressive or oncogenic activity in the context of their role in psychiatric disorders. The expression pattern of a variety of different microRNAs was investigated in patients (N = 6 suffering from schizophrenia termed control, patients with a solid tumor (N = 10 and patients with both schizophrenia and tumor (N = 8. miRNA profiling was performed on whole blood samples using the miRCURY LNA microRNA Array technology (6th & 7th generation. A subset of 3 microRNAs showed a statistically significant differential expression between the control and the study groups. Specifically, significant down-regulation of the let-7p-5p, miR-98-5p and of miR-183-5p in the study groups (tumor alone and tumorand schizophrenia was observed (p<0.05. The results of the present study showed that let-7, miR-98 and miR-183 may play an important oncosuppressive role through their regulatory impact in gene expression irrespective of the presence of schizophrenia, although a larger sample size is required to validate these results. Nevertheless, further studies are warranted in order to highlight a possible role of these and other micro-RNAs in the molecular pathways of schizophrenia.

Considerations on Directive 98/8 of the European Commission - the biocide directive.

Science.gov (United States)

Patryn, Rafał; Jarosz, Mirosław J; Włoszczak-Szubzda, Anna; Sak, Jarosław; Pawlikowski, Jakub

2011-01-01

Nowadays, versatile human activity requires the development of technologies in the chemical and biological industries that ultimately enable an increase in human activity, and help create the living conditions in the domain of human civilization. Increasing this activity very frequently requires the implementation of new technologies concerning the active elimination of numerous threats and obstacles which are found in the human and natural environment. The concept of so-called biocidal products has been introduced into the European legislation as long as ten years ago, defining them as various types of 'chemical substances or microorganisms which can deter, render harmless, or exert a controlling eff ect on any harmful organism, by chemical or biological means'. They can be added to other materials (typically liquids) to protect them against biological infestation and growth. Biocidal products - due to their specificity, toxicity and composition - create a serious risk for human and animal life and health, as well as for the natural environment, it is therefore fully justified to have legal regulations concerning such biocides. Because biocidal products are intended to kill living organisms, and as such, many biocidal products pose a significant risk to human health and welfare, and have significant adverse eff ects on the natural environment. Great care is required when handling biocides and appropriate protective clothing and equipment should be used. Currently, Directive 98/8/EC is a comprehensive set of legal regulations concerning biocidal products, their specificity, principles relating to their placing on the market, and guidelines for their control. It is worth emphasizing that Directive 98/8/EC implements the clampdown on poisoning cases with biocides, the duty of which was passed to the so-called Centres of Consultation and Toxicological Information. These centres provide round-the-clock (24-hour) medical consultation and assistance in cases of

hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.

Directory of Open Access Journals (Sweden)

Alicia Pérez-González

Full Text Available hCLE/C14orf166 is a nuclear and cytoplasmic protein that interacts with the RNAP II, modulates nuclear RNA metabolism and is present in cytoplasmic RNA granules involved in localized translation. Here we have studied whether hCLE shares common interactors in the nucleus and the cytosol, which could shed light on its participation in the sequential phases of RNA metabolism. Nuclear and cytoplasmic purified hCLE-associated factors were identified and proteins involved in mRNA metabolism, motor-related proteins, cytoskeletal and translation-related factors were found. Purified hCLE complexes also contain RNAs and as expected some hCLE-interacting proteins (DDX1, HSPC117, FAM98B were found both in the nucleus and the cytoplasm. Moreover, endogenous hCLE fractionates in protein complexes together with DDX1, HSPC117 and FAM98B and silencing of hCLE down-regulates their nuclear and cytosolic accumulation levels. Using a photoactivatable hCLE-GFP protein, nuclear import and export of hCLE was observed indicating that hCLE is a shuttling protein. Interestingly, hCLE nuclear import required active transcription, as did the import of DDX1, HSPC117 and FAM98B proteins. The data indicate that hCLE probably as a complex with DDX1, HSPC117 and FAM98B shuttles between the nucleus and the cytoplasm transporting RNAs suggesting that this complex has a prominent role on nuclear and cytoplasmic RNA fate.

WIN Global. 1977/98 Activities at a First Glance

International Nuclear Information System (INIS)

Rising, A.; Lopez CArbonell, M.T.; Perez-Griffo, M.L.

1998-01-01

WIN is a worldwide association of women working professionally in the fields of nuclear energy and applications of radiation. The goal of WIN is to contribute to objectively inform the public on nuclear and radiation. WIN's principal objective is to emphasis and support the role that women can and do have in addressing the general public's concerns about nuclear energy and the application of radiation and nuclear technology. WIN is doing this through educational programmes, information exchange and arranging study visits. Members of WIN all have one thing in common: they want the general public to have a better understanding of nuclear and radiation matters. Membership status as ao April 21, 1998 was 605 members from 39 countries. During the year 7 new countries have joined to WIN ant two national WIN groups have been formed. Purpose of this paper is to present, to the Spanish Nuclear Society members, the WIN Global activities all over the world for the period 1997/98. The information included herein comes from different sources and WIN members and is, of course, a quick look over those activities. Win Spain activities for the period will be presented in a different paper of this Annual Meeting. (Author) 2 refs

CYP98A22, a phenolic ester 3’-hydroxylase specialized in the synthesis of chlorogenic acid, as a new tool for enhancing the furanocoumarin concentration in Ruta graveolens

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Karamat Fazeelat

2012-08-01

Full Text Available Abstract Background Furanocoumarins are molecules with proven therapeutic properties and are produced in only a small number of medicinal plant species such as Ruta graveolens. In vivo, these molecules play a protective role against phytophageous insect attack. Furanocoumarins are members of the phenylpropanoids family, and their biosynthetic pathway is initiated from p-coumaroyl coA. The enzymes belonging to the CYP98A cytochrome P450 family have been widely described as being aromatic meta-hydroxylases of various substrates, such as p-coumaroyl ester derivatives, and are involved in the synthesis of coumarins such as scopoletin. In furanocoumarin-producing plants, these enzymes catalyze the step directly downstream of the junction with the furanocoumarin biosynthetic pathway and might indirectly impact their synthesis. Results In this work, we describe the cloning and functional characterization of the first CYP98A encoding gene isolated from R. graveolens. Using Nicotiana benthamiana as a heterologous expression system, we have demonstrated that this enzyme adds a 3-OH to p-coumaroyl ester derivatives but is more efficient to convert p-coumaroyl quinate into chlorogenic acid than to metabolize p-coumaroyl shikimate. Plants exposed to UV-B stress showed an enhanced expression level of the corresponding gene. The R. graveolens cyp98a22 open reading frame and the orthologous Arabidopsis thaliana cyp98a3 open reading frame were overexpressed in stable transgenic Ruta plants. Both plant series were analyzed for their production of scopoletin and furanocoumarin. A detailed analysis indicates that both genes enhance the production of furanocoumarins but that CYP98A22, unlike CYP98A3, doesn’t affect the synthesis of scopoletin. Conclusions The overexpression of CYP98A22 positively impacts the concentration of furanocoumarins in R. graveolens. This gene is therefore a valuable tool to engineer plants with improved therapeutical values that might

Comparison of the multi-drug resistant human hepatocellular carcinoma cell line Bel-7402/ADM model established by three methods

Directory of Open Access Journals (Sweden)

Zhong Xingguo

2010-08-01

Full Text Available Abstract Background To compare the biological characteristics of three types of human hepatocellular carcinoma multi-drug resistant cell sub-lines Bel-7402/ADM models established by three methods. Methods Established human hepatocellular carcinoma adriamycin (ADM multi-drug resistant cell sub-lines models Bel-7402/ADMV, Bel-7402/ADML and Bel-7402/ADMS by three methods of in vitro concentration gradient increased induction, nude mice liver-implanted induction and subcutaneous-implanted induction respectively. Phase contrast microscopy was used to observe the cells and the MTT (methyl thiazolyl tetrazolium method was used to detect drug resistance of the three different sub-lines of cells. Results The three groups of drug resistant cells, Bel-7402/ADMV, Bel-7402/ADML and Bel-7402/ADMS generated cross-resistance to ADM and CDDP (cis-Diaminedichloroplatinum, but showed a significant difference in resistance to Bel-7402 IC50 value (P V, 46 h (Bel-7402/ADML, and 45 h (Bel-7402/ADMS. The excretion rates of ADM were significantly increased compared with the parent cell (34.14% line and were 81.06% (Bel-7402/ADMV, 66.56% (Bel-7402/ADML and 61.56% (Bel-7402/ADMS. Expression of P-gp and MRP in the three groups of resistant cells was significantly enhanced (P P > 0.05. Conclusions Stable resistance was involved in the resistant cell line model established by the above three methods. Liver implantation was a good simulation of human hepatocellular and proved to be an ideal model with characteristics similar to human hepatocellular biology and the pharmacokinetics of anticancer drugs.

DFT study of the structures and energetics of 98-atom AuPd clusters.

Science.gov (United States)

Bruma, Alina; Ismail, Ramli; Paz-Borbón, L Oliver; Arslan, Haydar; Barcaro, Giovanni; Fortunelli, Alessandro; Li, Z Y; Johnston, Roy L

2013-01-21

The energetics, structures and segregation of 98-atom AuPd nanoclusters are investigated using a genetic algorithm global optimization technique with the Gupta empirical potential (comparing three different potential parameterisations) followed by local minimizations using Density Functional Theory (DFT) calculations. A shell optimization program algorithm is employed in order to study the energetics of the highly symmetric Leary Tetrahedron (LT) structure and optimization of the chemical ordering of a number of structural motifs is carried out using the Basin Hopping Monte Carlo approach. Although one of the empirical potentials is found to favour the LT structure, it is shown that Marks Decahedral and mixed FCC-HCP motifs are lowest in energy at the DFT level.

The Swedish Nuclear Power Inspectorate`s evaluation of SKB`s RD and D Program 98. Summary and conclusions

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-04-01

Compared to previous programmes, RD and D Programme 98 is focused to a greater extent on method and site selection and on issues relating to the decision-making process. This is natural, since the programme is now approaching the stage where vital decisions will have to be made. The RD and D Programme 98 report is supplemented by a background report `Detailed Programme for Research and Development 1999-2004` as well as a number of main references `System Reporting`, `Alternative methods`, `Criteria for Site Evaluation` and the `North-South/Coast-Interior` report. In addition, a number of references are available in the form of county-specific general siting studies, feasibility studies etc. SKI has distributed RD and D Programme 98 to sixty-three reviewing bodies for comment. The reviewing bodies include universities and institutes of technology, local safety committees, municipalities hosting nuclear facilities and municipalities participating in feasibility studies as well as many authorities. The comments of the reviewing bodies mainly focused on the decision-making process, including issues relating to method selection and site selection and, in particular, on the selection of sites for site investigation. Several reviewing bodies, particularly universities and institutes of technology, have also submitted comments of a more technical-scientific nature. SKI`s evaluation has focused on determining whether SKB`s programme can be considered to fulfil the requirements stipulated in the Act on Nuclear Activities that such a programme should be able to result in the implementation of solutions for the final disposal of the spent nuclear fuel from the Swedish nuclear power programme. Furthermore, SKI`s evaluation has also focused on the conditions that SKI considers should apply to SKB`s future work. Specific comments are made for the following areas: Decision-making process, Method selection and system analysis, Siting, Technical development, Safety assessments

Histoire et mémoire de Gorée dans la traite atlantique : paramnésie ...

African Journals Online (AJOL)

29 mai 2015 ... Conseil pour le développement de la recherche en sciences sociales en Afrique,. 2014 (ISSN 0850-3907) ... La controverse de « Gorée et l'esclavage : mythes et réalités » a eu deux effets. ... d'Internet. En août 1995 par ...

The Effect of G-ORS Along With Rice Soup in the Treatment of Acute Diarrhea in Children: A Single-Blind Randomized Controlled Trial.

Science.gov (United States)

Kianmehr, Mojtaba; Saber, Ashraf; Moshari, Jalil; Ahmadi, Reza; Basiri-Moghadam, Mahdi

2016-06-01

The world health organization guidelines for treatment of diarrhea in children emphasize on continued feeding together with prescription of oral rehydration solution (ORS) and supplementary zinc therapy. However, conflicting viewpoints exist regarding the optimal diet and dietary ingredients for children with diarrhea. Moreover, few studies have investigated the effect of rice soup along with ORS in the treatment of this disease. This study aimed to explore effects of simultaneous taking of glucose oral rehydration solution (G-ORS) and rice soup in the treatment of acute diarrhea in 8 to 24-month-old children. This single-blind controlled clinical trial was conducted in the pediatric ward of 22nd of Bahman hospital, Gonabad, Iran between June 2013 and February 2014. Forty children aged 8-24 months with acute diarrhea were randomly assigned into an intervention group (G-ORS plus rice soup group) comprising 20 babies and a control group (G-ORS) of 20 children based on balanced blocking randomization. The variables under investigation were diarrhea duration, patient hospitalization, need for intravenous (IV) fluids and stool output frequency. Data was analyzed using independent samples t and chi-square test. At the end of study, the time for treating acute watery diarrhea in the intervention and control groups were 21.10 ± 8.81 and 34.55 ± 5.82 hours (P < 0.001) and hospital stay were 34.05 ± 6.62 and 40.20 ± 6.32 hours (P = 0.005). Moreover, stool output frequency were 4.20 ± 0.95 and 8.00 ± 1.37 (P < 0.001) in the first 24 hours, and 2.18 ± 0.60 and 2.80 ± 0.76 (P = 0.03) in the second 24 hours of treatment in intervention and control groups, respectively. Rice soup regimen was highly effective and inexpensive in the treatment of acute diarrhea in children. Thus, in addition to the common treatment by G-ORS, rice soup can be consumed simultaneously with G-ORS.

Antigen-presenting cells exposed to Lactobacillus acidophilus NCFM, Bifidobacterium bifidum BI-98, and BI-504 reduce regulatory T cell activity

DEFF Research Database (Denmark)

Schmidt, Esben Gjerløff Wedebye; Claesson, Mogens Helweg; Jensen, Simon Skjøde

2010-01-01

BACKGROUND:: The effect in vitro of six different probiotic strains including Lactobacillus acidophilus NCFM, Lactobacillus salivarius Ls-33, Lactobacillus paracasei subsp. paracasei YS8866441, Lactobacillus plantarum Lp-115, Bifidobacterium bifidum BI-504 and BI-98 was studied on splenic...

Final Technical Report for Award DE-FG02-98ER41080

Energy Technology Data Exchange (ETDEWEB)

Chen, Alan

2014-11-14

The prime motivation of the project at McMaster University was to carry out the critical evaluation and compilation of Nuclear Structure and Decay data, and of nuclear astrophysics data with continued participation in the United States Nuclear Data Program (US-NDP). A large body of evaluated and compiled structure data were supplied for databases such as ENSDF, XUNDL, NSR, etc. residing on webpage of National Nuclear Data Center of the Brookhaven National Laboratory, Upton, New York, USA. Thermonuclear reaction rates of importance to stellar explosions, such as novae, x-ray bursts and supernovae, were evaluated as well. This effort was closely coupled to our ongoing experimental effort, which took advantage of radioactive ion beam and stable beam facilities worldwide to study these key reaction rates. This report contains brief descriptions of the various activities together with references to all the publications in peer-reviewed journals which were the result of work carried out with the award DE-FG02-98-ER41080, during 1998-2013.

Bel-Robinson energy and the nature of singularities in isotropic cosmologies

International Nuclear Information System (INIS)

Klaoudatou, Ifigeneia; Cotsakis, Spiros

2007-01-01

We review our recent work on the classification of finite time singularities that arise in isotropic universes. This scheme is based on the exploitation of the Bel Robinson energy in a cosmological setting. We comment on the relation between geodesic completeness and the Bel Robinson energy and present evidence that relates the divergence of the latter to the existence of closed trapped surfaces

Propriedades morfológicas do peritônio da paca (Cuniculus paca, L. 1766 a fresco e conservados em glicerina 98%

Directory of Open Access Journals (Sweden)

Angela Daniele De Camargo

2012-09-01

Full Text Available http://dx.doi.org/10.5007/2175-7925.2012v25n4p185   Objetivou-se, com este estudo, descrever as características morfológicas de amostras de peritônio a fresco e conservadas em glicerina a 98%, por períodos de 30, 60 e 90 dias, de quatro pacas adultas. As amostras foram analisadas por meio da microscopia de luz e microscopia eletrônica de varredura. Verificou-se um evidente arranjo entre o tecido conjuntivo denso modelado e o tecido conjuntivo denso não modelado, além de insignificante modificação na integridade tecidual do peritônio da paca, quando submetida a ação da glicerina nos diferentes períodos. Conclui-se que o peritônio da paca pode ser utilizado como mais uma opção de material biológico.

1: Mass asymmetric fission barriers for {sup 98}Mo; 2: Synthesis and characterization of actinide-specific chelating agents

Energy Technology Data Exchange (ETDEWEB)

Veeck, A.C. [Univ. of California, Berkeley, CA (United States). Dept. of Chemistry]|[Lawrence Livermore National Lab., CA (United States). Glenn T. Seaborg Inst. for Transactinium Science]|[Lawrence Berkeley National Lab., CA (United States). Nuclear Science Div.

1996-08-01

Excitation functions have been measured for complex fragment emission from the compound nucleus {sup 98}Mo, produced by the reaction of {sup 86}Kr with {sup 12}C. Mass asymmetric fission barriers have been obtained by fitting the excitation functions with a transition state formalism. The extracted barriers are {approximately} 5.7 MeV higher, on average, than the calculations of the Rotating Finite Range Model (RFRM). These data clearly show an isospin dependence of the conditional barriers when compared with the extracted barriers from {sup 90}Mo and {sup 94}Mo. Eleven different liquid/liquid extractants were synthesized based upon the chelating moieties 3,2-HOPO and 3,4-HOPO; additionally, two liquid/liquid extractants based upon the 1,2-HOPO chelating moiety were obtained for extraction studies. The Pu(IV) extractions, quite surprisingly, yielded results that were very different from the Fe(III) extractions. The first trend remained the same: the 1,2-HOPOs were the best extractants, followed closely by the 3,2-HOPOs, followed by the 3,4-HOPOs; but in these Pu(IV) extractions the 3,4-HOPOs performed much better than in the Fe(III) extractions. 129 refs.

Anti-irradiation performance against helium bombardment in bulk metallic glass (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5}

Energy Technology Data Exchange (ETDEWEB)

Mei, Xianxiu, E-mail: xxmei@dlut.edu.cn [Key Laboratory of Materials Modification by Laser, Ion and Electron Beams, Dalian University of Technology, Ministry of Education, Dalian 116024 (China); Wang, Bin; Dong, Chuang; Gong, Faquan; Wang, Younian [Key Laboratory of Materials Modification by Laser, Ion and Electron Beams, Dalian University of Technology, Ministry of Education, Dalian 116024 (China); Wang, Zhiguang [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)

2013-07-15

Highlights: ► This paper used He{sup 2+} ion-irradiated metallic glass (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5} and the W metal with the energy of 500 keV. ► There was no significant irradiation damage phenomenon on the surface of metallic glass at different irradiation fluences. ► For irradiated W, the peeling, delamination and flaking appeared numerously at fluences of 1 × 10{sup 18} and 2 × 10{sup 18} ions/cm{sup 2}. ► The resistance to He{sup 2+} irradiation of metallic glass (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5} was superior to the one in W metal. -- Abstract: In order to compare the resistance to He{sup 2+} ion induced irradiation between metallic glass and polycrystal W metal, this paper used different fluences of He{sup 2+} ion-irradiated metallic glass (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5} and polycrystal W with an energy of 500 keV. The SRIM simulation calculation results showed that the range (1.19 μm) of He{sup 2+} in metallic glass was greater than the one (0.76 μm) in polycrystal W. The SEM analysis showed that there was no significant irradiation damage phenomenon on the surface of metallic glass, and there was only a damage layer 1.45 μm away from the surface when the fluence reached 2 × 10{sup 18} ions/cm{sup 2}. For W, there were surface peeling, flaking and other surface damages at a fluence of 1 × 10{sup 18} ions/cm{sup 2}; when the fluence increased to 2 × 10{sup 18} ions/cm{sup 2}, multilayer detachment phenomenon appeared. The surface root mean square roughness of metallic glass (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5} first increased and then decreased with the increase of fluence. The surface reflectivity of (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5} decreased with the increase of fluence. Through detection by XRD, it was found that (Cu{sub 47}Zr{sub 45}Al{sub 8}){sub 98.5}Y{sub 1.5} always maintained amorphous phase after different fluences of radiation. The

Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

Directory of Open Access Journals (Sweden)

Yee-Wen Ng

2018-04-01

Full Text Available Background Obesity-related central nervous system (CNS pathologies like neuroinflammation and reactive gliosis are associated with high-fat diet (HFD related elevation of saturated fatty acids like palmitic acid (PA in neurons and astrocytes of the brain. Methods Human neuroblastoma cells SH-SY5Y (as a neuronal model and human glioblastoma cells T98G (as an astrocytic model, were treated with 100–500 µM PA, oleic acid (OA or lauric acid (LA for 24 h or 48 h, and their cell viability was assessed by 3-(4,5-dimetylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay. The effects of stable overexpression of γ-synuclein (γ-syn, a neuronal protein recently recognized as a novel regulator of lipid handling in adipocytes, and transient overexpression of Parkinson’s disease (PD α-synuclein [α-syn; wild-type (wt and its pathogenic mutants A53T, A30P and E46K] in SH-SY5Y and T98G cells, were also evaluated. The effects of co-treatment of PA with paraquat (PQ, a Parkinsonian pesticide, and leptin, a hormone involved in the brain-adipose axis, were also assessed. Cell death mode and cell cycle were analyzed by Annexin V/PI flow cytometry. Reactive oxygen species (ROS level was determined using 2′,7′-dichlorofluorescien diacetate (DCFH-DA assay and lipid peroxidation level was determined using thiobarbituric acid reactive substances (TBARS assay. Results MTT assay revealed dose- and time-dependent PA cytotoxicity on SH-SY5Y and T98G cells, but not OA and LA. The cytotoxicity was significantly lower in SH-SY5Y-γ-syn cells, while transient overexpression of wt α-syn or its PD mutants (A30P and E46K, but not A53T modestly (but still significantly rescued the cytotoxicity of PA in SH-SY5Y and T98G cells. Co-treatment of increasing concentrations of PQ exacerbated PA’s neurotoxicity. Pre-treatment of leptin, an anti-apoptotic adipokine, did not successfully rescue SH-SY5Y cells from PA-induced cytotoxicity—suggesting a mechanism of PA

Analysis of statistical distributions of partial γ-widths of 98Mo neutron 3 2-resonances

International Nuclear Information System (INIS)

Knat'ko, V.A.; Rudak, Eh.A.; Shimanovich, E.A.

1978-01-01

Width distributions for E1 γ-transitions from the 98 Mo neutron 3/2 resonances to the 99 Mo low-lying levels with 1/2 + , 3/2 2 and 5/2 + spins are desribed. Considered are sets of widths corresponding to γ-transitions to the levels with 3/2 spin and positioned in the energy range from 12 to 5268 eV. On the basis of the results obtained a conclusion has been drawn that the width distribution of γ-transitions to the 3/2 + level differs from the Porter-Thomas distribution

Ice storm '98: The electricity industry's great challenge

International Nuclear Information System (INIS)

Anon.

1998-01-01

The biggest and most costly natural disaster to hit Canada in over a century, the ice storms of 1998, that transformed Eastern Canada into a virtual glacier, was discussed. Trees, wires, poles, transmission towers, transformers succumbed to the immense weight of the ice, countless transmission and distribution lines were destroyed, leaving millions in the dark and cold, many for several weeks. The unprecedented show of solidarity within the electricity industry, as hundreds of crews from utilities across Canada and the U.S., the many thousands of private individuals and some 16,000 members of the Canadian Forces that came to the assistance of those in the affected areas, working 16-hour days, braving falling trees and sub-zero temperatures, was truly astonishing, and clearly the stuff of which legends are made. The storm has humbled Canadian public authorities and especially the Canadian electricity industry. Besides honoring those that weathered the storm, and paying tribute to the utilities and private companies that reached out to assist in the relief efforts, this review also discusses the need for government agencies and utility companies to review their emergency preparedness plans. The objective is to improve them by incorporating the most important lessons learned from this experience, in an effort to forestall their future recurrence. It is generally accepted that the Ice Storm of '98 was a unique natural disaster that no amount of planning could have foreseen, much less prevented. Nevertheless, by examining the lessons learned, it might be possible to reduce the severity should a similar disaster occur again

Preliminary evaluation of FY98 KALIMER shielding design

Energy Technology Data Exchange (ETDEWEB)

Yoo, Jae Woon; Kang, Chang Mu; Kim, Young Jin [Korea Atomic Energy Research Institute, Taejon (Korea)

1999-01-01

This report describes a preliminary evaluation of the shielding design of FY98 KALIMER. The KALIMER shielding design includes the Inner Fixed Shield of a stainless cylinder located inside the support barrel; the Radial PSDRS Shields which are three B{sub 4}C cylinders located outside the support barrel at core level; the Lower IHX shield of a cylindrical B{sub 4}C plate located above the flow guide; and Inner and Outer IHX shields of B{sub 4}C cylinders located inside and outside of the support barrel, respectively. The DORT3.1 two-dimensional transport code was used to evaluate the KALIMER shielding design. The reactor system was represented by four axial zones, each of which was modeled in the R-Z geometry. The KAFAX-F22 library was used in the analyses, which was generated from the JEF-2.2 of OECD/NEA files for LMR applications by KAERI. The performance of the KALIMER shielding design is compared against the shielding design criteria. The results indicate that the support barrel, upper grid plate, and other reactor structures meet the maximum neutron fluence and DPA limits established in the shielding design criteria. Activities of the air effluent in the PSDRS were also evaluated and are shown to satisfy the maximum permissible concentration (MPC) limits in 10 CFR Part 20. In the future, the validation of the DORT model by a detailed three dimensional calculation such as MCNP and the justification of the current shielding design limits are needed. (author). 13 refs., 23 figs., 31 tabs.

Spectral analysis of the IntCal98 calibration curve: a Bayesian view

International Nuclear Information System (INIS)

Palonen, V.; Tikkanen, P.

2004-01-01

Preliminary results from a Bayesian approach to find periodicities in the IntCal98 calibration curve are given. It has been shown in the literature that the discrete Fourier transform (Schuster periodogram) corresponds to the use of an approximate Bayesian model of one harmonic frequency and Gaussian noise. Advantages of the Bayesian approach include the possibility to use models for variable, attenuated and multiple frequencies, the capability to analyze unevenly spaced data and the possibility to assess the significance and uncertainties of spectral estimates. In this work, a new Bayesian model using random walk noise to take care of the trend in the data is developed. Both Bayesian models are described and the first results of the new model are reported and compared with results from straightforward discrete-Fourier-transform and maximum-entropy-method spectral analyses

The Swedish Nuclear Power Inspectorate's evaluation of SKB's RD and D Program 98. Review report

International Nuclear Information System (INIS)

1999-04-01

According to the Act (1984:3) on Nuclear Activities, the full responsibility for the safe management and final disposal of spent nuclear fuel and nuclear waste rests with the owners of the Swedish nuclear power reactors. In accordance with the Act (1992:1537) on the Financing of Future Expenses for Spent Nuclear Fuel etc., the owners are also responsible for ensuring that funds are set aside to cover the future expenses of the management and final disposal of spent nuclear fuel and nuclear waste. Furthermore, nuclear reactor owners must conduct, and every three years, submit a research and development programme for the management of the spent nuclear fuel and nuclear waste. The programme must also cover the measures which are necessary for the decommissioning and dismantling of the nuclear installations. SKI must submit the programme documents to the Government, along with its own statement. The owners of the nuclear power reactors have formed a joint company, SKB which, on behalf of the owners, fulfils the owners' statutory obligations with respect to the management and final disposal of spent nuclear fuel and nuclear waste and conducts related research and development. The programme now submitted by SKB is the latest in the series which started with RandD Programme 86. The current programme was submitted in September 1998 and is called RDandD Programme 98 (programme for Research, Development and Demonstration). In RDandD Programme 98, SKB has stated that it particularly welcomes viewpoints concerning: Whether deep disposal according to the KBS-3 method will continue to be the preferred method. The body of material that SKB is compiling in preparation for the selection of sites for site investigation. What is to be included in future Environmental Impact Statements (EIS). Compared to previous programmes, RDandD Programme 98 is focused to a greater extent on method and site selection and on issues relating to the decision-making process. In order to emphasise that

Identification of anti-CD98 antibody mimotopes for inducing antibodies with antitumor activity by mimotope immunization.

Science.gov (United States)

Saito, Misa; Kondo, Masahiro; Ohshima, Motohiro; Deguchi, Kazuki; Hayashi, Hideki; Inoue, Kazuyuki; Tsuji, Daiki; Masuko, Takashi; Itoh, Kunihiko

2014-04-01

A mimotope is an antibody-epitope-mimicking peptide retrieved from a phage display random peptide library. Immunization with antitumor antibody-derived mimotopes is promising for inducing antitumor immunity in hosts. In this study, we isolated linear and constrained mimotopes from HBJ127, a tumor-suppressing anti-CD98 heavy chain mAb, and determined their abilities for induction of antitumor activity equal to that of the parent antibody. We detected elevated levels of antipeptide responses, but failed to detect reactivity against native CD98-expressing HeLa cells in sera of immunized mice. Phage display panning and selection of mimotope-immunized mouse spleen-derived antibody Fab library showed that HeLa cell-reactive Fabs were successfully retrieved from the library. This finding indicates that native antigen-reactive Fab clones represented an undetectable minor population in mimotope-induced antibody repertoire. Functional and structural analysis of retrieved Fab clones revealed that they were almost identical to the parent antibody. From these results, we confirmed that mimotope immunization was promising for retrieving antitumor antibodies equivalent to the parent antibody, although the co-administration of adjuvant compounds such as T-cell epitope peptides and Toll-like receptor 4 agonist peptides is likely to be necessary for inducing stronger antitumor immunity than mimotope injection alone. © 2014 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

Search of collectivity at N >= 52 via lifetime measurements in ^96-98Ru

Science.gov (United States)

Kharraja, B.; Garg, U.; Ghugre, S. S.; Frohlich, A.; Ahmad, I.; Amro, H.; Blumenthal, D.; Carpenter, M. P.; Crowell, B.; Fisher, S.; Janssens, R. V. F.; Khoo, T. L.; Lauritsen, T.; Nissius, D.; Reviol, W.; Mueller, W.; Govil, I. M.; Ma, W. C.; Kaczarowski, R.; Ruchowska, E.

1996-05-01

Level structures of nuclei with N ~ 50 and Z ~ 40 exhibit interesting interplay between the single particle and collective degrees of freedom. Lifetime measurements are crucial to ascertain the intrinsic structures of the observed level sequences in this region and, specificaly to verify the onset of collectivity. This motivated us to undertake lifetime measurements using the RDM technique for ^96-98Ru nuclei. These nuclei were populated via the ^65Cu(^36Si,pyn) reaction at 142 MeV, and the Argonne-Notre Dame γ-ray facility was employed in conjonction with the Notre Dame plunger. Data were connected in coincidence at 12 distances rangin from 10 μm to 1000 μm giving us an effective lifetime range 1 ps to 400 ps.

Cell suspension culture-mediated incorporation of the rice bel gene into transgenic cotton.

Directory of Open Access Journals (Sweden)

Liping Ke

Full Text Available Cotton plants engineered for resistance to the herbicides, glyphosate or glufosinate have made a considerable impact on the production of the crop worldwide. In this work, embryogenic cell cultures derived from Gossypium hirsutum L. cv Coker 312 hypocotyl callus were transformed via Agrobacterium tumefaciens with the rice cytochrome P450 gene, CYP81A6 (bel. In rice, bel has been shown to confer resistance to both bentazon and sulfanylurea herbicides. Transformed cells were selected on a liquid medium supplemented alternately or simultaneously with kanamycin (50mg/L and bentazon (4.2 µmol. A total of 17 transgenic cotton lines were recovered, based on the initial resistance to bentazon and on PCR detection of the bel transgene. Bel integration into the cotton genome was confirmed by Southern blot and expression of the transgene was verified by RT-PCR. In greenhouse and experimental plot trials, herbicide (bentazon tolerance of up to 1250 mg/L was demonstrated in the transgenic plants. Transgenic lines with a single copy of the bel gene showed normal Mendelian inheritance of the characteristic. Importantly, resistance to bentazon was shown to be stably incorporated in the T1, T2 and T3 generations of self-fertilised descendents and in plants outcrossed to another upland cotton cultivar. Engineering resistance to bentazon in cotton through the heterologous expression of bel opens the possibility of incorporating this trait into elite cultivars, a strategy that would give growers a more flexible alternative to weed management in cotton crops.

The discovery of 9/8-ribbons, β/γ-peptides with curved shapes governed by a combined configuration-conformation code.

Science.gov (United States)

Grison, Claire M; Robin, Sylvie; Aitken, David J

2015-11-21

The de novo design of a β/γ-peptidic foldamer motif has led to the discovery of an unprecedented 9/8-ribbon featuring an uninterrupted alternating C9/C8 hydrogen-bonding network. The ribbons adopt partially curved topologies determined synchronistically by the β-residue configuration and the γ-residue conformation sets.

Preliminary study of MR diffusion weighted imaging in nude mice models of hepatic Bel7402 tumors after adenovirus-mediated cytosine diaminase-thymidine kinase gene therapy

International Nuclear Information System (INIS)

Jiang Xinqing; Chen Liang; Wu Hongzhen; Huang Jingjun; Wei Xinhua; Mo Lei; Yang Ruimeng; Xiao Xiangsheng

2012-01-01

Objective: To study the characteristics of DWI in nude mice models of hepatic Bel7402 tumors after treatment with adenovirus-mediated cytosine diaminase-thymidine kinase (Ad. CD-TK) double suicide gene therapy, and then to identify whether DWI can be used for assessing curative effect of postoperative tumors. Methods: Thirty nude mice models of hepatic Bel7402 tumors were successfully created using cell suspension method, after the tumor grew to more than 1 cm in diameter, 20 tumor models were treated by intratumoral administration of Ad. CD-TK for 3 days plus intraperitonea (i.p.) treatment with 5-Fc and GCV for the duration of the study.Then they were randomly divided into three groups during 5-Fc and GCV treatment. The remaining 10 tumor models were used as controls. MR scanning were performed in 10 th day before and after tumor implantation in all models by using EPI-SE series and SENSE technology for treatment group. Tumor volumes and ADC values were calculated pretreatment and posttreatment. Cell apoptosis were determined by using TUNEL method. Analyze the change of ADC and apoptosis index (AI) in different times, t test was used for comparison the difference of AI and ADC values respectively. Results: After 10 days,the tumor volumes of the treatment groups and controls were respectively (724.16 ±57.45) mm 3 , (754.57 ± 66.84) mm 3 , with no significant difference (t=0.488, P >0.05). The ADC values of the treatment groups were (0.98 ±0.11) × 10 -3 mm 2 /s,the ones of the control groups were (0.68 ±0.04) × 10 -3 mm 2 /s; AI of the treatment groups were (23.25 ±6.57)%, the ones of the control groups were (2.57 ± 0.58)%. There were difference in both groups (t=4.473, 5.874; P<0.01). Conclusion: DWI can be effectively to monitor the early pathological changes of hepatic Bel7402 tumors after Ad. CD-TK double suicide gene therapy, and provide experimental evidences for clinical application. (authors)

A carboxymethyl cellulase from a marine yeast ( Aureobasidium pullulans 98): Its purification, characterization, gene cloning and carboxymethyl cellulose digestion

Science.gov (United States)

Rong, Yanjun; Zhang, Liang; Chi, Zhenming; Wang, Xianghong

2015-10-01

We have reported that A. pullulans 98 produces a high yield of cellulase. In this study, a carboxymethyl cellulase (CMCase) in the supernatant of the culture of A. pullulans 98 was purified to homogeneity, and the maximum production of CMCase was 4.51 U (mg protein)-1. The SDS-PAGE analysis showed that the molecular mass of the purified CMCase was 67.0 kDa. The optimal temperature of the purified enzyme with considerable thermosensitivity was 40°C, much lower than that of the CMCases from other fungi. The optimal pH of the enzyme was 5.6, and the activity profile was stable in a range of acidity (pH 5.0-6.0). The enzyme was activated by Na+, Mg2+, Ca2+, K+, Fe2+ and Cu2+, however, it was inhibited by Fe3+, Ba2+, Zn2+, Mn2+ and Ag+. K m and V max values of the purified enzyme were 4.7 mg mL-1 and 0.57 µmol L-1 min-1 (mg protein)-1, respectively. Only oligosaccharides with different sizes were released from carboxymethylcellulose (CMC) after hydrolysis with the purified CMCase. The putative gene encoding CMCase was cloned from A. pullulans 98, which contained an open reading frame of 954 bp (EU978473). The protein deduced contained the conserved domain of cellulase superfamily (glucosyl hydrolase family 5). The N-terminal amino acid sequence of the purified CMCase was M-A-P-H-A-E-P-Q-S-Q-T-T-E-Q-T-S-S-G-Q-F, which was consistent with that deduced from the cloned gene. This suggested that the purified CMCase was indeed encoded by the cloned CMCase gene in this yeast.

Nd{sub 39}Ir{sub 10.98}In{sub 36.02}. A complex intergrowth structure with CsCl- and AlB{sub 2}-related slabs

Energy Technology Data Exchange (ETDEWEB)

Dominyuk, Nataliya; Zaremba, Vasyl' I. [Ivan Franko National Univ., Lviv (Ukraine). Dept. of Inorganic Chemistry; Rodewald, Ute C.; Poettgen, Rainer [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie

2015-11-01

The ternary indide Nd{sub 39}Ir{sub 10.98}In{sub 36.02} was synthesized by arc-melting and characterized by single crystal X-ray diffraction. Nd{sub 39}Ir{sub 10.98}In{sub 36.02} crystallizes with a new structure type: Pearson code oP172, Pbam, a = 3175.4(6), b = 3762.5(8), c = 378.02(8) pm, wR2 = 0.0828, 5544 F{sup 2} values, and 262 variables. Although the structure contains 44 crystallographically independent sites, it can easily be explained as an intergrowth structure of CsCl and AlB{sub 2} related slabs. The larger indium atoms fill all distorted CsCl slabs. The trigonal prismatic (AlB{sub 2}) slabs have no uniform size. The larger ones are filled by indium and the smaller ones by the iridium atoms. Additionally, one trigonal prism shows a mixed occupancy by indium and iridium. The crystal chemistry of Nd{sub 39}Ir{sub 10.98}In{sub 36.02} is discussed in the context of other intergrowth structures with the same simple slabs.

Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study

DEFF Research Database (Denmark)

Borgquist, Signe; Giobbie-Hurder, Anita; Ahern, Thomas P

2017-01-01

on cholesterol levels and hypercholesterolemia per se may counteract the intended effect of aromatase inhibitors. Patients and Methods The Breast International Group (BIG) conducted a randomized, phase III, double-blind trial, BIG 1-98, which enrolled 8,010 postmenopausal women with early-stage, hormone receptor......-positive invasive breast cancer from 1998 to 2003. Systemic levels of total cholesterol and use of CLM were measured at study entry and every 6 months up to 5.5 years. Cumulative incidence functions were used to describe the initiation of CLM in the presence of competing risks. Marginal structural Cox proportional...

36 CFR 1256.98 - Can I get access to and obtain copies of USIA audiovisual records transferred to the National...

Science.gov (United States)

2010-07-01

... obtain copies of USIA audiovisual records transferred to the National Archives of the United States? 1256... United States Information Agency Audiovisual Materials in the National Archives of the United States § 1256.98 Can I get access to and obtain copies of USIA audiovisual records transferred to the National...

Psalm 98: Sing ’n nuwe lied tot lof van die Koning, Jahwe

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W. S. Prinsloo

1994-01-01

Full Text Available Sing a new song in praise of the king, Yahweh This article surveys the problems of interpreting Psalm 98. The chief problems are those concerned with determining the Gattung, the redactional history, strophic division and the dating of the Psalm. A textimmanent reading of the Psalm is used in an effort to make a significant contribution to the debate. The conclusion arrived at is that the Psalm forms a coherent, artistic whole and that a variety of poetic techniques is used in its composition. The poetic function of the Psalm can be described as persuasive. That is to say, the Psalm is intended to persuade the reader/auditor that Yahweh is worthy of praise and that his dependability is manifest in his acts of salvation.

Euratom framework programme research in reactor safety main achievements of FP-4 ('94-'98), some preliminary results of FP-5 ('98-'02) and prospects for beyond 2002

Energy Technology Data Exchange (ETDEWEB)

Goethem, G. van; Martin Bermejo, J.; Zurita, A.; Lemaitre, P. [Commission of the European Communities, Brussels (BE). Directorate General for Science, Research and Development (DG 12)

2001-07-01

In this paper an overview is given of the most important aspects of the research activities organised by the European union (EU) in reactor safety, more specifically in the area ''Operational Safety of Existing Installations'', which is one of the 4 areas of the key action Nuclear Fission in the 5th Euratom framework programme (FP-5). In the introduction, a short description is given of the EU needs and the new boundary conditions for Euratom research. In the next 7 sections, the attention is drawn to a series of technical and socio-economical facts, which generate needs at the EU level and hence justify some actions - especially in terms of research - at the Commission level. The following needs have been identified and are proposed for discussion: to maintain the nuclear option open in order to ensure flexibility in energy supply; to maintain scientific and technical competence; to maintain industrial competitiveness and to prepare the next generation of reactors; to maintain a broad nuclear expertise covering both energetic and non-energetic applications; to develop environment-friendly sustainable solutions for the wastes; to share and improve the safety culture amongst the EU countries and the CEECs; and finally, to focus on public benefit and on added European value in Euratom research actions. A brief overview then is given of the European response - in terms of research - offered up to 2002 to contribute to meet some of the above needs, i.e. the Euratom research actions under FP-4 ('94-'98) and FP-5 ('98-'02). As far as the future beyond 2002 is concerned, the challenge to Euratom research is to identify networks of excellence and to reorganize itself in line with the new ERA concept (European research area). Finally conclusions are drawn on the perceived need to improve the fitness-for-purpose of Euratom research actions in the ''changing world'' and to rethink accordingly the organisation of

OF THE GREAT TEMPLE OF BEL

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A. Denker

2017-02-01

Full Text Available The Great Temple of Bel in Palmyra was a unique edifice which had blended the well established lines of Greco-Roman architecture with the art and taste of the Orient. With the gilded bronze capitals of its 41 Corinthian columns it was the product of enormous effort and budget. It was the gem of a remarkable epoch of wealthy Palmyra and mighty Roma. With its splendidly decorated adyta ceilings it became a source of inspiration and imagination for Western architecture and decorative arts. While continuing to captivate the World, it was leveled and vanished as a grim result of conflict based vandalism. The aim of this work is to piece together this, the most eloquent and stupendous monument of the Roman East, from its ruins and reconstruct it as it was once extant. Its loss is irreplacable, but its photo-realistic reconstruction can offer some solace by waking the memories of the great temple as in the past. The lost reality of the Great Temple of Bel is revived here by digitally constructing its “ghost images".

A new organically templated gallium(III)-doped chromium(III) fluorophosphite, (C2H10N2)[Ga0.98Cr0.02(HPO3)F3] hydrothermal synthesis, crystal structure and spectroscopic properties

International Nuclear Information System (INIS)

Fernandez-Armas, Sergio; Mesa, J.L.; Pizarro, J.L.; Lezama, Luis; Arriortua, M.I.; Rojo, T.

2004-01-01

A new organically templated fluoro-phosphite gallium(III)-doped chromium(III) with formula (C 2 H 10 N 2 )[Ga 0.98 Cr 0.02 (HPO 3 )F 3 ] has been synthesized by using mild hydrothermal conditions under autogeneous pressure. The crystal structure has been solved from X-ray single-crystal data. The compound crystallizes in the P2 1 2 1 2 1 orthorhombic space group, with the unit-cell parameters a=12.9417(7) A, b=9.4027(6) A, c=6.3502(4) A and Z=4. The final R factors were R1=0.022 (all data) and wR2=0.050. The crystal structure consists of [Ga 0.98 Cr 0.02 (HPO 3 )F 3 ] 2- anionic chains extended along the c-axis, with the ethylenediammonium cations placed in the cavities of the structure delimited by three different chains. The IR and Raman spectra show the characteristic bands of the phosphite oxoanion. The diffuse reflectance spectroscopy allowed us to calculate the Dq and Racah parameters of the Cr(III) cations in octahedral environment. The values are Dq=1375 cm -1 , B=780 cm -1 and C=3420 cm -1 . The polycrystalline ESR spectra performed at X and Q-bands show the signals belonging to the diluted Cr(III) cation in this phase. From the fit of the X-band ESR spectrum at 4.2 K, the calculated values of the axial (D) and rhombic (E) distortion parameters are 0.075 and 0.042 cm -1 , respectively, the components of the g-tensor being g x =1.98, g y =1.99 and g z =1.90

Calmodulin 2 Mutation N98S Is Associated with Unexplained Cardiac Arrest in Infants Due to Low Clinical Penetrance Electrical Disorders.

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Juan Jiménez-Jáimez

Full Text Available Calmodulin 1, 2 and 3 (CALM mutations have been found to cause cardiac arrest in children at a very early age. The underlying aetiology described is long QT syndrome (LQTS, catecholaminergic polymorphic ventricular tachycardia (CPVT and idiopathic ventricular fibrillation (IVF. Little phenotypical data about CALM2 mutations is available.The aim of this paper is to describe the clinical manifestations of the Asn98Ser mutation in CALM2 in two unrelated children in southern Spain with apparently unexplained cardiac arrest/death.Two unrelated children aged 4 and 7, who were born to healthy parents, were studied. Both presented with sudden cardiac arrest. The first was resuscitated after a VF episode, and the second died suddenly. In both cases the baseline QTc interval was within normal limits. Peripheral blood DNA was available to perform targeted gene sequencing.The surviving 4-year-old girl had a positive epinephrine test for LQTS, and polymorphic ventricular ectopic beats were seen on a previous 24-hour Holter recording from the deceased 7-year-old boy, suggestive of a possible underlying CPVT phenotype. A p.Asn98Ser mutation in CALM2 was detected in both cases. This affected a highly conserved across species residue, and the location in the protein was adjacent to critical calcium binding loops in the calmodulin carboxyl-terminal domain, predicting a high pathogenic effect.Human calmodulin 2 mutation p.Asn98Ser is associated with sudden cardiac death in childhood with a variable clinical penetrance. Our results provide new phenotypical information about clinical behaviour of this mutation.

ENVIRONMENTAL TECHNOLOGY VERIFICATION, TEST REPORT OF CONTROL OF BIOAEROSOLS IN HVAC SYSTEMS, FILTRATION GROUP, AEROSTAR FP-98 MINIPLEAT V-BLANK FILTER

Science.gov (United States)

The Environmental Technology Verification report discusses the technology and performance of the AeroStar FP-98 Minipleat V-Bank Filter air filter for dust and bioaerosol filtration manufactured by Filtration Group. The pressure drop across the filter was 137 Pa clean and 348 Pa ...

Synergistic effect of cisplatin and synchrotron irradiation on F98 gliomas growing in nude mice

Energy Technology Data Exchange (ETDEWEB)

Ricard, Clement; Fernandez, Manuel [Grenoble Institut des Neurosciences, Grenoble (France); Université Joseph Fourier, Grenoble (France); Requardt, Herwig [European Synchrotron Radiation Facility, Grenoble (France); Wion, Didier [Grenoble Institut des Neurosciences, Grenoble (France); Université Joseph Fourier, Grenoble (France); Vial, Jean-Claude [Université Joseph Fourier, Grenoble (France); Laboratoire Interdisciplinaire de Physique, St Martin d’Hères (France); Segebarth, Christoph; Sanden, Boudewijn van der, E-mail: boudewijn.vandersanden@ujf-grenoble.fr [Grenoble Institut des Neurosciences, Grenoble (France); Université Joseph Fourier, Grenoble (France)

2013-09-01

Synchrotron photoactivation therapy of cisplatin relies on a synergistic effect of synchrotron X-rays and platinum and leads to tumor-cell-killing effects and reduction of the tumor blood perfusion. Among brain tumors, glioblastoma multiforme appears as one of the most aggressive forms of cancer with poor prognosis and no curative treatment available. Recently, a new kind of radio-chemotherapy has been developed using synchrotron irradiation for the photoactivation of molecules with high-Z elements such as cisplatin (PAT-Plat). This protocol showed a cure of 33% of rats bearing the F98 glioma but the efficiency of the treatment was only measured in terms of overall survival. Here, characterization of the effects of the PAT-Plat on tumor volume and tumor blood perfusion are proposed. Changes in these parameters may predict the overall survival. Firstly, changes in tumor growth of the F98 glioma implanted in the hindlimb of nude mice after the PAT-Plat treatment and its different modalities have been characterized. Secondly, the effects of the treatment on tumor blood perfusion have been observed by intravital two-photon microscopy. Cisplatin alone had no detectable effect on the tumor volume. A reduction of tumor growth was measured after a 15 Gy synchrotron irradiation, but the whole therapy (15 Gy irradiation + cisplatin) showed the largest decrease in tumor growth, indicating a synergistic effect of both synchrotron irradiation and cisplatin treatment. A high number of unperfused vessels (52%) were observed in the peritumoral area in comparison with untreated controls. In the PAT-Plat protocol the transient tumor growth reduction may be due to synergistic interactions of tumor-cell-killing effects and reduction of the tumor blood perfusion.

Over-expression of CYP78A98, a cytochrome P450 gene from Jatropha curcas L., increases seed size of transgenic tobacco

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Yinshuai Tian

2016-01-01

Conclusions: The results indicated that CYP78A98 played a role in Jatropha seed size control. This may help us to better understand the genetic regulation of Jatropha seed development, and accelerate the breeding progress of Jatropha.

Renal tumors: evaluation of prognostic factors in 98 cases from a reference hospital in Porto Alegre, Brazil

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Alexandra Medeiros Souza de Freitas

2014-02-01

Full Text Available Introduction: Renal cell carcinoma (RCC is an aggressive disease worldwide. Objective: Study traditional prognostic factors associated with pathological reports and the novel markers survivin and B7-H1 by immunohistochemistry. Methods: In a reference hospital of Porto Alegre, Brazil, we conducted a cross-sectional study of RCC in patients who underwent radical nephrectomy between 2006 and 2009. We selected those who were diagnosed with the most common histologic subtypes: clear cell and papillary RCC. We retrospectively reviewed pathological data to determine traditional prognostic factors, like size, presence of coagulative necrosis, Fuhrman grade and tumor-node metastasis (TNM system. Besides, we performed an immunohistochemistry (IHC study with survivin and B7-H1. Results: Our sample had 98 cases, 90% of the cases were composed by clear cell histologic subtype, 73% were tumors classified as T1 and T2 in the TNM system, most were Fuhrman nuclear grade 2 or 3, and 70% were positive for necrosis. In relation to the new prognostic markers, we found 50 cases positive to survivin and 38 to B7-H1. In this investigation of traditional prognostic markers and new markers we observed that only necrosis was associated with positive results of biomarkers. < 0.001. Conclusion: This finding confirms previous studies that necrosis is an important factor to consider in the prognosis of RCC.

Corrosion '98: 53. annual conference and exposition, proceedings

International Nuclear Information System (INIS)

Anon.

1998-01-01

This conference was divided into the following sections: Corrosion in Gas Treating; Problems and Solutions in Commercial Building Water Systems; Green Corrosion/Scale Inhibitors; Atmospheric Corrosion; AIRPOL Update/98; Rubber Lining--Answers to Many Problems; Interference Problems; Environmental Assisted Cracking: Fundamental Research and Industrial Applications; Corrosion in Nuclear Systems; New Developments in Scale and Deposit Control; Corrosion and Corrosion Protection in the Transportation Industries; What's All the Noise About--Electrochemical That Is; Refining Industry Corrosion; Corrosion Problems in Military Hardware: Case Histories, Fixes and Lessons Learned; Cathodic Protection Test Methods and Instrumentation for Underground and On-grade Pipelines and Tanks; Recent Developments in Volatile Corrosion Inhibitors; Corrosion in Supercritical Fluids; Microbiologically Influenced Corrosion; Advances in Understanding and Controlling CO 2 Corrosion; Managing Corrosion with Plastics; Material Developments for Use in Exploration and Production Environments; Corrosion in Cold Regions; The Effect of Downsizing and Outsourcing on Cooling System Monitoring and Control Practices; New Developments in Mechanical and Chemical Industrial Cleaning; Mineral Scale Deposit Control in Oilfield Related Operations; Biocides in Cooling Water; Corrosion and Corrosion Control of Reinforced Concrete Structures; Materials Performance for Fossil Energy Conversion Systems; Marine corrosion; Thermal Spray--Coating and Corrosion Control; Flow Effects on Corrosion in Oil and Gas Production; Corrosion Measurement Technologies; Internal Pipeline Monitoring--Corrosion Monitoring, Intelligent Pigging and Leak Detection; Cathodic Protection in Natural Waters; Corrosion in Radioactive Liquid Waste Systems; On-line Hydrogen Permeation Monitoring Equipment and Techniques, State of the Art; Water Reuse and Recovery; Performance of Materials in High Temperature Environments; Advances in Motor

The relationship between waiting times and 'adherence' to the Scottish Intercollegiate Guidelines Network 98 guideline in autism spectrum disorder diagnostic services in Scotland.

Science.gov (United States)

McKenzie, Karen; Forsyth, Kirsty; O'Hare, Anne; McClure, Iain; Rutherford, Marion; Murray, Aja; Irvine, Linda

2016-05-01

The aim of this study was to explore the extent to which the Scottish Intercollegiate Guidelines Network 98 guidelines on the assessment and diagnosis of autism spectrum disorder were adhered to in child autism spectrum disorder diagnostic services in Scotland and whether there was a significant relationship between routine practice which more closely reflected these recommendations (increased adherence) and increased waiting times. Retrospective, cross-sectional case note analysis was applied to data from 80 case notes. Adherence ranged from a possible 0 (no adherence) to 19 (full adherence). Overall, 17/22 of the recommendations were adhered to in over 50 of the 80 cases and in 70 or more cases for 11/22 of the recommendations, with a mean adherence score of 16 (standard deviation = 1.9). No significant correlation was found between adherence and total wait time for untransformed (r = 0.15, p = 0.32) or transformed data (r = 0.12, p = 0.20). The results indicated that the assessment and diagnostic practices were consistent with the relevant Scottish Intercollegiate Guidelines Network 98 guideline recommendations. Increased adherence to the 19 included recommendations was not significantly related to increased total waiting times, indicating that the Scottish Intercollegiate Guidelines Network 98 recommendations have generally been integrated into practice, without a resultant increase in patient waits. © The Author(s) 2015.

Early Musical Training in Bel Canto Vocal Technique: A Brief History and Philosophy.

Science.gov (United States)

Gerstein, Christine Wondolowski

This paper offers a brief history and philosophy of the origins of bel canto vocal style and describes the pedagogical methods used to achieve bel canto ideals in singing. The document discusses the adoption and development of this technique and how it developed over long periods of preparation in the foregoing centuries before the Baroque era.…

Daniel Dragonslayer – Bel and the dragon, Verses 23−27 (OG/Th

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Joseph J. de Bruyn

2015-04-01

Full Text Available In this article, aspects of narrative critique, genre, editorial critique, the body and space are uniquely combined into a body-space framework. This spatial framework is used to examine the second episode of ‘Bel and the Dragon’, called ‘Daniel Dragonslayer’. It is postulated that the second episode of ‘Bel and the Dragon’ should be read in a reciprocal relationship with not only ‘Bel and the Dragon’, but also the larger Book of Daniel. Firstly, such an analysis indicates that the smaller episode is part of a larger clash of deities. Secondly, it shows that the editor /author utilises the episode to create a new cosmology. In this new cosmology, the Jewish deity is an almighty one, whilst other deities are seen as false and not real living gods. In his own way, the editor or author contributes to the way in which Jews regarded their God within the reality of the diaspora. Daniel Dragonslayer − Bel en die draak, Verse 23−27 (VAN/Die. In hierdie artikel word aspekte van narratiewe-kritiek, genre, redaksie-kritiek, die liggaam en ruimte op ’n unieke wyse gekombineer om ’n beliggaamde ruimteraamwerk te vorm. Hierdie beliggaamde ruimteraamwerk word gebruik om die tweede episode van ‘Bel en die Draak’, naamlik ‘Daniël, die Draakjagter’, te analiseer. Die artikel stel voor dat hierdie tweede episode van ‘Bel en die Draak’ in ’n resiproke verhouding met ‘Bel en die Draak’, sowel as met die boek Daniël gelees moet word. Indien die teks op hierdie voorgestelde wyse ontleed word, kom verskeie punte na vore. Eerstens word aangedui dat die kleiner episode deel van ’n groter gode-oorlog vorm. Tweedens, die skrywer/redakteur gebruik die kleiner episode as deel van ’n proses om ’n nuwe kosmologie te skep. Volgens hierdie nuwe kosmologie is die Joodse God ’n almagtige God, terwyl ander gode vals en nie ware lewende gode is nie. Op sy eie manier lewer die skrywer/redakteur ’n bydrae tot die

DECHEMA annual conference in 1998; DECHEMA-Jahrestagungen `98. Bd. 1. 16. Jahrestagung der Biotechnologen. Kurzfassungen

Energy Technology Data Exchange (ETDEWEB)

Hess, C. [comp.

1998-12-31

In a versatile, often multidisciplinary programme the DECHEMA annual conferences in 1998 present new results from research, the state of the art, and, not least, the persons, companies, and institutions active in various disciplines. This volume contains shortened versions of the lectures and posters presented at the 16th Annual Conference of Biotechnologists. [Deutsch] Die DECHEMA-Jahrestagungen `98 stellen in einem vielseitigen, oft interdisziplinaeren Programm neue Ergebnisse aus der Forschung, den aktuellen Stand der Technik und nicht zuletzt auch die auf den jeweiligen Gebieten aktiven Personen, Firmen und Institutionen vor. In diesem Band sind die Kurzfassungen der Vortraege und Poster der 16. Jahrestagung der Biotechnologen enthalten. (orig.)

DECHEMA annual conference in 1998; DECHEMA-Jahrestagungen `98. Bd. 1. 16. Jahrestagung der Biotechnologen. Kurzfassungen

Energy Technology Data Exchange (ETDEWEB)

Hess, C [comp.

1999-12-31

In a versatile, often multidisciplinary programme the DECHEMA annual conferences in 1998 present new results from research, the state of the art, and, not least, the persons, companies, and institutions active in various disciplines. This volume contains shortened versions of the lectures and posters presented at the 16th Annual Conference of Biotechnologists. [Deutsch] Die DECHEMA-Jahrestagungen `98 stellen in einem vielseitigen, oft interdisziplinaeren Programm neue Ergebnisse aus der Forschung, den aktuellen Stand der Technik und nicht zuletzt auch die auf den jeweiligen Gebieten aktiven Personen, Firmen und Institutionen vor. In diesem Band sind die Kurzfassungen der Vortraege und Poster der 16. Jahrestagung der Biotechnologen enthalten. (orig.)

An Expectation of a backbending for N> 98 of a rare earth nuclei

Energy Technology Data Exchange (ETDEWEB)

Salah, M M [Physics Dept., Faculty of Science, Minia University, (Egypt); El-Elgebaly, H [Physics Dept., Faculty of Science, Cairo University, Cairo (Egypt)

1997-12-31

The backbending of three neighboring earth nuclei [Er-Yb-Hf] with their isotopes has been studied through the cubic polynomial (CP) theoretical model in addition to [Ex vs. I (I+I)] and [0 vs.{sub 2}] plots, at high energy angular momentum in nuclear rotational bands according to the values of R 4. Also the rotational nuclei are divided into soft and hard rotors by studying the softness S. We expected that there may be a backbending for nuclei of N> 98, but with a High angular momentum, which were not expected before by studying the effect of (I+I) at the critical spin of a backbending. The work includes study of the effective moment of inertia 0eff for these nuclei, and the theoretical treatment to reduce the error in energy calculation of (CP) model. 5 figs., 1 tab.

Identification of two new mutations in the GPR98 and the PDE6B genes segregating in a Tunisian family.

Science.gov (United States)

Hmani-Aifa, Mounira; Benzina, Zeineb; Zulfiqar, Fareeha; Dhouib, Houria; Shahzadi, Amber; Ghorbel, Abdelmonem; Rebaï, Ahmed; Söderkvist, Peter; Riazuddin, Sheikh; Kimberling, William J; Ayadi, Hammadi

2009-04-01

Autosomal recessive retinitis pigmentosa (ARRP) is a genetically heterogeneous disorder. ARRP could be associated with extraocular manifestations that define specific syndromes such as Usher syndrome (USH) characterized by retinal degeneration and congenital hearing loss (HL). The USH type II (USH2) associates RP and mild-to-moderate HL with preserved vestibular function. At least three genes USH2A, the very large G-protein-coupled receptor, GPR98, and DFNB31 are responsible for USH2 syndrome. Here, we report on the segregation of non-syndromic ARRP and USH2 syndrome in a consanguineous Tunisian family, which was previously used to define USH2B locus. With regard to the co-occurrence of these two different pathologies, clinical and genetic reanalysis of the extended family showed (i) phenotypic heterogeneity within USH2 patients and (ii) excluded linkage to USH2B locus. Indeed, linkage analysis disclosed the cosegregation of the USH2 phenotype with the USH2C locus markers, D5S428 and D5S618, whereas the ARRP perfectly segregates with PDE6B flanking markers D4S3360 and D4S2930. Molecular analysis revealed two new missense mutations, p.Y6044C and p.W807R, occurring in GPR98 and PDE6B genes, respectively. In conclusion, our results show that the USH2B locus at chromosome 3p23-24.2 does not exist, and we therefore withdraw this locus designation. The combination of molecular findings for GPR98 and PDE6B genes enable us to explain the phenotypic heterogeneity and particularly the severe ocular affection first observed in one USH2 patient. This report presents an illustration of how consanguinity could increase familial clustering of multiple hereditary diseases within the same family.

A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians

DEFF Research Database (Denmark)

Anuradha, Shekher; Radha, Venkatesan; Deepa, Raj

2005-01-01

Among Europeans, mutations in the hepatocyte nuclear factor-1alpha (HNF1alpha) gene are associated with the most common form of maturity-onset diabetes of the young (MODY)3. In Asian Indians, type 2 diabetes occurs earlier and often overlaps with MODY, but the genetics of the latter are unknown....... The aim of this study was to estimate the prevalence of Ala98Val polymorphism of the HNF1alpha gene in different types of diabetes in Asian Indians....

Development of NRESP98 Monte Carlo codes for the calculation of neutron response functions of neutron detectors. Calculation of the response function of spherical BF{sub 3} proportional counter

Energy Technology Data Exchange (ETDEWEB)

Hashimoto, M.; Saito, K.; Ando, H. [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center

1998-05-01

The method to calculate the response function of spherical BF{sub 3} proportional counter, which is commonly used as neutron dose rate meter and neutron spectrometer with multi moderator system, is developed. As the calculation code for evaluating the response function, the existing code series NRESP, the Monte Carlo code for the calculation of response function of neutron detectors, is selected. However, the application scope of the existing NRESP is restricted, the NRESP98 is tuned as generally applicable code, with expansion of the geometrical condition, the applicable element, etc. The NRESP98 is tested with the response function of the spherical BF{sub 3} proportional counter. Including the effect of the distribution of amplification factor, the detailed evaluation of the charged particle transportation and the effect of the statistical distribution, the result of NRESP98 calculation fit the experience within {+-}10%. (author)

DEWEK '98: 4. German wind power conference; DEWEK '98: 4. Deutsche Windenergie-Konferenz. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

Gerdes, B [ed.

1999-07-01

The conference report comprises 90 papers and posters on the following subjects: 1. Technological developments (e.g. use of adaptive structures systems, active stalle wind power systems, systems for early detection of errors); 2. Design and optimisation; 3. Wind forecasts; 4. Operation analyses (e.g. active and passive stall, collective loads, wind power systems in cold climates); 5. Wind power systems and the environment; 6. Offshore wind power generation; 7. Electric characteristics (e.g. modelling of flicker, energy conditioning in distribution systems with a high wind power share); 8. Economic efficiency (e.g. economic efficiency of offshore wind parks on the North Sea coast); 9. Network quality; 10. Rotor development (e.g. noise reduction); 11. Certification and methods of measurement. [German] Der Tagungsband enhaelt 90 Fach- und Posterbeitraege, die sich mit den folgenden Schwerpunkten befassen: 1. Technologische Entwicklungen (z.B. Einsatz von adaptiven Struktursystemen; Active-Stall-WKA; Fehlerfrueherkennungssystemen). 2. Auslegung und Optimierung. 3. Windprognosen. 4. Betriebsanalysen (z.B. Aktive Stall/Passive Stall im Vergleich; Lastkollektive von WKA; WKA in kaltem Klima). 5. Windenergieanlagen und Umwelt. 6. Offshore-Windenergienutzung. 7. Elektrische Eigenschaften (z.B. Modellierung des 'Flickerverhaltens' von WKA; Energiekonditionierung in Verteilnetzen mit hohem Windenergieanteil). 8. Wirtschaftlichkeit (z.B. Wirtschaftlichkeit von Offshore-Windparks der Norddeutschen Kuestenlinie). 9. Netzqualitaet. 10. Rotorentwicklung (z.B. Reduzierung der Schallabstrahlung von WKAs). 11. Zertifizierung von Messmethoden. (AKF)

Formation of the City of Belém (PA: Central Area and its Paper Historical and Geographical

Directory of Open Access Journals (Sweden)

Antônio Carlos Ribeiro Araújo Júnior

2012-12-01

Full Text Available In the 17th Century the urban life of Belém spread out from a promontorylocated at the meeting point of Guajará Bay and Guamá River. These "natural obstacles" (waterways, floodplains and flooded forest presented momentary setbacks to urban expansion. Overcoming these obstacles the city of Belém developed a central area characerized by change and continuity. By identifying and analyzing historical and geographical changes in the central area of Belém a better understanding can be obtained of new functions and features of urban space in Belém today.

5kW phase-shifted full-bridge converter with current doubler using normally-off SiC JFETs designed for 98% efficiency

DEFF Research Database (Denmark)

Török, Lajos; Beczkowski, Szymon; Munk-Nielsen, Stig

2013-01-01

In this paper a 5kW step-down converter for low-voltage high-current application is presented using normally-off SiC JFETs as high voltage power switches, operating with efficiency close to 98%. Different low voltage side rectification solutions and loss estimations are also presented. As results...

Impacto de "El Niño 1997-98" sobre el ecosistema marino somero de la costa central del Perú

Directory of Open Access Journals (Sweden)

Juan Tarazona B.

2014-06-01

Full Text Available Se analizó las características de intensidad y precocidad de las respuestas a "El Niño 1997-98" manifestada por el fitoplancton superficial, macroalgas de la orilla rocosa y macrobentos de fondo blando en la Bahía de Ancón (11º46' LS y 77211' LW, entre diciembre de 1996 y agosto de 1998. Este evento se caracterizó por un incremento significativo de la temperatura desde abril (17,4ºC y del oxígeno (2,46 mi x l" a partir de mayo de 1997, en los fondos del área de estudio. En el fitoplancton superficial se registró la presencia de especies indicadoras de aguas oceánicas cálidas desde enero y un inusual aumento en la densidad de dinoflagelados y microflagelados a inicios de abril de 1997. La densidad de la población de la macroalga Chondracanthus chamissoi alcanzó 2 684 indo x 32 m' de línea de orilla en octubre de 1997, y la proporción de gametofitos se incrementó durante 1998. La densidad y el número de especies del macrobentos de fondo blando alcanzaron los valores máximos de 90 indo x 0,04 m•2 y 20 especies en junio y noviembre de 1997, respectivamente; estas variaciones correlacionaron bien con los cambios en la intensidad de "El Niño". La biomasa llegó a su máximo valor de 0,55 g pssc x 0,04 m•2 recién en enero de 1998. Finalmente, se demuestra que el impacto biológico de "El Niño 1997-98" fue menor al del evento de 1982-83, no obstante la similitud en la intensidad de ambos eventos; y que las aguas someras presentaron indicadores tempranos y confiables de "El Niño", tanto en el fitoplancton como en el bentos. Además, la presencia de un período post-Niño demuestra que el impacto de "El Niño" sobre las poblaciones y comunidades puede ser complejo.

ENC'98 world nuclear congress and exhibition, RECOD 98 the fifth international conference on recycling, conditioning and disposal. Transactions. Volume 1. Opening session

International Nuclear Information System (INIS)

1998-01-01

ENC'98, this four yearly conference - held alongside the world's largest nuclear exhibition - is one of a small number of major international meetings to attract delegates from right across the nuclear energy spectrum. As such, the event provides an invaluable opportunity to take stock of the industry's position in the energy market, measure its technological progress, devise strategies that will help secure its long-term future, and assess its standing with the general public - a factor which we all know will have a bearing on its very survival. Looking back over the four years that have gone by since the last ENC, it is easy to conclude from figures on power station construction, electricity output and market share, that nuclear has, at best, stood still. But, as we all know, statistics can mislead or fail to convey the full picture. In many countries the privatisation of power utilities and liberalization of the energy market is throwing down the commercial gauntlet. The industry, I am happy to say, is responding with vigour. Up-rating programmes, improvement in fuel performance and equipment upgrades are among the many measures successfully being taken to reduce costs and improve competitiveness while maintaining the highest standards of safety. Add to this the advances being made in new reactor technology, improvements in cross border collaboration, joint venture arrangements and progress on the harmonization of regulatory standards, and we have a sound basis for believing a more outward looking industry, far from marking time, is in a state of healthy transition. (author)

Emission Scenario Document for Biocides Emission scenarios for all 23 product types of the Biocidal Products Directive (EU Directive 98/8/EC)

NARCIS (Netherlands)

Poel P van der; Bakker J; CSR

2002-01-01

Dit rapport geeft een overzicht van de beschikbare emissiescenario's voor niet-landbouwbestrijdingsmiddelen voor alle 23 productgroepen uit de biocide richtlijn (EU Richtlijn 98/8/EC). Het betreft scenario's die reeds in USES 3.0 zijn opgenomen, alsmede scenario's die

Sambandet mellan Theory of Mind, språkliga förmågor och exekutiva funktioner hos barn i treårsåldern

OpenAIRE

Nilsson, Anna; Sirén, Ellen

2015-01-01

Barns fem första levnadsår präglas av en omfattande utveckling av språkliga förmågor och exekutiva funktioner, vilka är färdigheter som visat sig ha en stor påverkan på hur barn utvecklar förståelse för sina egna och andras tankar, det vill säga deras Theory of Mind. En central aspekt inom forskning har varit att undersöka hur förmågorna samvarierar vid olika åldrar. Syftet i föreliggande studie var att undersöka sambandet mellan Theory of Mind, språkliga förmågor och exekutiva funktioner hos...

Noorte uimastikäitumise perekondlikest tagamaadest : [küsitlusuuringu ESPAD ja elanikkonnaküsitluse "Eesti 98" andmetel] / Kati Hammer-Pratka

Index Scriptorium Estoniae

Hammer-Pratka, Kati

2001-01-01

Artiklis uuritakse noorte uimastikäitumise võimalikke perekondlikke mõjutegureid. Analüüsitakse teismeliste laste vanemate seotust alkoholi, suitsetamise ja narkootikumidega ning nende riskitunnetust uimastite tarbimise suhtes. Kasutatud on kahe küsitluse - 1999.a. Euroopa Kooliõpilaste Alkoholi ja Narkootikumide Kasutamise Küsitlusuuringu (ESPAD, viidi läbi 20 riigis) ja elanikkonnaküsitluse "Eesti '98" materjale

AUS98 - The 1998 version of the AUS modular neutronic code system

Energy Technology Data Exchange (ETDEWEB)

Robinson, G.S.; Harrington, B.V

1998-07-01

AUS is a neutronics code system which may be used for calculations of a wide range of fission reactors, fusion blankets and other neutron applications. The present version, AUS98, has a nuclear cross section library based on ENDF/B-VI and includes modules which provide for reactor lattice calculations, one-dimensional transport calculations, multi-dimensional diffusion calculations, cell and whole reactor burnup calculations, and flexible editing of results. Calculations of multi-region resonance shielding, coupled neutron and photon transport, energy deposition, fission product inventory and neutron diffusion are combined within the one code system. The major changes from the previous AUS publications are the inclusion of a cross-section library based on ENDF/B-VI, the addition of the MICBURN module for controlling whole reactor burnup calculations, and changes to the system as a consequence of moving from IBM main-frame computers to UNIX workstations This report gives details of all system aspects of AUS and all modules except the POW3D multi-dimensional diffusion module refs., tabs.

AUS98 - The 1998 version of the AUS modular neutronic code system

International Nuclear Information System (INIS)

Robinson, G.S.; Harrington, B.V.

1998-07-01

AUS is a neutronics code system which may be used for calculations of a wide range of fission reactors, fusion blankets and other neutron applications. The present version, AUS98, has a nuclear cross section library based on ENDF/B-VI and includes modules which provide for reactor lattice calculations, one-dimensional transport calculations, multi-dimensional diffusion calculations, cell and whole reactor burnup calculations, and flexible editing of results. Calculations of multi-region resonance shielding, coupled neutron and photon transport, energy deposition, fission product inventory and neutron diffusion are combined within the one code system. The major changes from the previous AUS publications are the inclusion of a cross-section library based on ENDF/B-VI, the addition of the MICBURN module for controlling whole reactor burnup calculations, and changes to the system as a consequence of moving from IBM main-frame computers to UNIX workstations This report gives details of all system aspects of AUS and all modules except the POW3D multi-dimensional diffusion module

BELIEF dashboard - a web-based curation interface to support generation of BEL networks

OpenAIRE

Madan, Sumit; Hodapp, Sven; Fluck, Juliane

2015-01-01

The relevance of network-based approaches in systems biology to achieve a better understanding of biological mechanisms has increased enormously. The Biological Expression Language (BEL) is well designed to collate findings from scientific literature into biological network models. To facilitate encoding and biocuration of such findings in BEL, a free and user-friendly web-based curation interface called BELIEF Dashboard has been developed. The interface incorporates an information extraction...

The effects of taking snacks on the learning ability and educational achievement of elementary school children, 1997-98

OpenAIRE

Alavi Naeini SM; Jazayeri SA; Moghaddam Banaem N; Afrooz Gh.A; Behboodi

2000-01-01

The effects of taking snacks on the learning ability and educational achievement of elementary school children in district 18 of Tehran educational organization were examined in the school year 1997-98. Other factors such as grade, nutritional status, breakfast eating habits and snack eating habits in the school were also studied. For this purpose 236 boys were selected by random sampling in 4 different schools. The children were randomly assigned to a group, with a low calorie snack (119 sub...

Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum β-Lactamase and Its Complexes with Moxalactam and Imipenem.

Science.gov (United States)

Pozzi, Cecilia; De Luca, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, Gian Maria; Mangani, Stefano; Docquier, Jean-Denis

2016-12-01

BEL-1 is an acquired class A extended-spectrum β-lactamase (ESBL) found in Pseudomonas aeruginosa clinical isolates from Belgium which is divergent from other ESBLs (maximum identity of 54% with GES-type enzymes). This enzyme is efficiently inhibited by clavulanate, imipenem, and moxalactam. Crystals of BEL-1 were obtained at pH 5.6, and the structure of native BEL-1 was determined from orthorhombic and monoclinic crystal forms at 1.60-Å and 1.48-Å resolution, respectively. By soaking native BEL-1 crystals, complexes with imipenem (monoclinic form, 1.79-Å resolution) and moxalactam (orthorhombic form, 1.85-Å resolution) were also obtained. In the acyl-enzyme complexes, imipenem and moxalactam differ by the position of the α-substituent and of the carbonyl oxygen (in or out of the oxyanion hole). More surprisingly, the Ω-loop, which includes the catalytically relevant residue Glu166, was found in different conformations in the various subunits, resulting in the Glu166 side chain being rotated out of the active site or even in displacement of its Cα atom up to approximately 10 Å. A BEL-1 variant showing the single Leu162Phe substitution (BEL-2) confers a higher level of resistance to CAZ, CTX, and FEP and shows significantly lower K m values than BEL-1, especially with oxyiminocephalosporins. BEL-1 Leu162 is located at the beginning of the Ω-loop and is surrounded by Phe72, Leu139, and Leu148 (contact distances, 3.5 to 3.9 Å). This small hydrophobic cavity could not reasonably accommodate the bulkier Phe162 found in BEL-2 without altering neighboring residues or the Ω-loop itself, thus likely causing an important alteration of the enzyme kinetic properties. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Quasilocal energy and the Bel-Robinson tensor

International Nuclear Information System (INIS)

Krishnasamy, Ilangkovan

1985-01-01

The general-relativistic field equations are examined from the point of view of a local inertial observer and a quasilocal definitions of energy-momentum is thereby obtained. This definition relates to the Bel-Robinson tensor and the approach is shown to be consistent with the result obtained from the definition of energy given by Hawking. (author)

Mööbel suvekodusse / Aili Ermel

Index Scriptorium Estoniae

Ermel, Aili

2008-01-01

2008. a. Milano messil "Salone Internazionale del Mobile" oli mööblit, mis projekteeritud ekstra õuele, aga oli ka sellist, mis sobib suvel õue ja talvel tuppa. Mööbel firmalt Cappellini, Gervason (disainer Paola Navone), Horm (disainer Mario Bellini), Zanotta (disainerid Gae Aulenti, Prospero Rasulo, Emaf Progetti, Roberto Barbieri), EMU (disainer Patricia Urquiola), Moroso (disainerid Nipa Doshi, Jonhatan Levien, Edward Van Vliet), Cassina (Tokujin Yoshioka) ja RODA. 14 värv. ill

International co-operation and the future of nuclear power. European Nuclear Congress '98, Nice, 26 October 1998

International Nuclear Information System (INIS)

ElBaradei, M.

1998-01-01

The document reproduces the text of the conference given by the Director General of the IAEA at the joint Opening Session of the European Nuclear Congress'98 (ENC) and RECOD in Nice, France, on 26 october 1998. The conference emphasized the importance of strengthened international co-operation in all areas relevant to the safe and peaceful use of nuclear energy, especially for power generation. As the only intergovernmental global organization dedicated to nuclear science and technology, the role of the IAEA is to serve as the international focal point for standard setting, independent analysis, technology transfer and oversight and verification

Unique characterization of the Bel-Robinson tensor

International Nuclear Information System (INIS)

Bergqvist, G; Lankinen, P

2004-01-01

We prove that a completely symmetric and trace-free rank-4 tensor is, up to sign, a Bel-Robinson-type tensor, i.e., the superenergy tensor of a tensor with the same algebraic symmetries as the Weyl tensor, if and only if it satisfies a certain quadratic identity. This may be seen as the first Rainich theory result for rank-4 tensors

Electric response of Pb0.99[(Zr0.90Sn0.10)0.968Ti0.032]0.98Nb0.02O3 ceramics to the shock-wave-induced ferroelectric-to-antiferroelectric phase transition

International Nuclear Information System (INIS)

Jiang Dongdong; Zhang Na; Feng Yujun; Du Jinmei; Gu Yan

2012-01-01

Highlights: ► Shock wave induces the FE-to-AFE phase transition in PbNb(Zr,Sn,Ti)O 3 . ► Depoling current due to phase transition depends on shock pressure and load resistance. ► Shock pressure promotes the phase transition in short-circuit case. ► Increasing load resistance decreases the released charge. - Abstract: Shock-wave-enforced ferroelectric (FE)-to-antiferroelectric (AFE) phase transition releases a large electrical polarization, having application in pulse power technology. In the present work, the depoling currents under shock wave compression were investigated in Pb 0.99 [(Zr 0.90 Sn 0.10 ) 0.968 Ti 0.032 ] 0.98 Nb 0.02 O 3 (PZST) ceramics with composition close to the FE/AFE phase boundary. Shock wave was generated by gas-gun and propagated in a direction perpendicular to the remanent polarization. It was found that the shock pressure promoted the phase transition under the short-circuit condition. The shock pressure dependence of the released charge was associated with the evolution of FE-to-AFE phase transition. The onset of phase transition was about 0.40 GPa and complete transformation occurred at 1.23 GPa. However, the released charge decreased with increasing load resistance. The reason may be that the electric field suppresses the phase transition in uncompressed zone and/or shock induces conductivity in compressed zone. Results lay the foundation for application of PZST ceramics in shock-activated power supply.

Las derechas españolas ante la crisis del 98

Directory of Open Access Journals (Sweden)

Pedro Carlos GONZÁLEZ CUEVAS

2010-02-01

Full Text Available RESUMEN: El "Desastre" español del 98 no puede considerarse como un hecho castizo de la historia nacional. Es un fenómeno europeo, que afectó a naciones como Francia, Italia y Portugal. Estos desastres de carácter militar coinciden, además, con un período de crisis intelectual —"revuelta contra el positivismo"— y con los inicios de procesos de transformación social y política. Todo lo cual generó, en la mayoría de los países europeos, una profunda crisis de legitimación de los sistemas políticos liberales y la decadencia de las ideologías políticas tradicionales, dando lugar al desarrollo, en el campo de la derecha, de un conservadurismo radical, cuyos máximos teorizantes fueron Charles Maurras y Maurice Barrés. En España, el avance hacia formas de conservadurismo radical o "nacionalismo integral" fue mucho más lento, debido a la emergencia de los nacionalismos periféricos catalán y vasco, a la debilidad del sentimiento nacional español, a la ausencia de reivindicaciones territoriales y de enemigos externos. No obstante, el conjunto de la derecha española de la época reaccionó ante el "Desastre" y ante los nuevos retos ideológicos y políticos con una sensación de interrogación, que les llevó a un replanteamiento de sus posiciones; a lo que hay que sumar las reflexiones de los regeneracionistas y de los representantes intelectuales del "espíritu del 98", cuyas reflexiones críticas sobre el "problema de España" introdujeron nuevas perspectivas en el desarrollo del nacionalismo español. Todo lo cual incidió decisivamente en la génesis posterior de la derecha radical española. Palabras Clave: Crisis finisecular, nacionalismo español, derechas políticas, regeneracionismos, intelectuales. ABSTRACT: The Spanish disaster of 1898 cannot be considered as a uniquely Spanish event in the history of the nation. It was a European phenomenon, which affected nations such as France, Italy and Portugal. These disasters

Emission Scenario Document for Biocides Emission scenarios for all 23 product types of the Biocidal Products Directive (EU Directive 98/8/EC)

NARCIS (Netherlands)

Poel P van der; Bakker J; CSR

2002-01-01

This report presents an overview of all available emission scenarios for all 23 product types of biocides according to EU Directive 98/8/EC. The scenarios presented are already present in USES 3.0 or have been reported by RIVM or within the scope of the project "Gathering, review and development of

España y los sefardíes. El desastre del 98 en El Avenir [continuación

Directory of Open Access Journals (Sweden)

Asenjo, Rosa

2005-12-01

Full Text Available The typical image of Spain created after 1492 would be kept by the modernising Ottoman Sephardic Jews on the eve of the 20th century, as shown by new literary genres such as journalism. Indeed, in newspapers dealing with historical and cultural aspects of contemporary Spain, the Sephardim seem unable to tranform the old stereotypes, fearing the consequences this change could have in the perception of their own identity. A series of articles about the «disaster of '98» published in the Salonican newspaper El Avenir, are an example of this situation.La visión tópica que se había ido creando sobre España después de 1492 se mantendrá entre los judíos sefardíes otomanos de finales del siglo XIX, a pesar de la llegada de la modernidad. Los sefardíes finiseculares parecen incapaces de cambiar esta imagen tópica porque su desaparición tendría repercusiones en la percepción de su propia identidad. El periodismo, uno de los nuevos géneros literarios adoptados por los sefardíes, refleja esos tópicos en las noticias de contenido histórico-cultural que se refieren a la España del momento. Un ejemplo de esta situación lo presentan las noticias publicadas con motivo del «desastre del 98» en el periódico salonicense El Avenir.

Obesity and risk of recurrence or death after adjuvant endocrine therapy with letrozole or tamoxifen in the breast international group 1-98 trial

DEFF Research Database (Denmark)

Ewertz, Marianne; Gray, Kathryn P; Regan, Meredith M

2012-01-01

To examine the association of baseline body mass index (BMI) with the risk of recurrence or death in postmenopausal women with early-stage breast cancer receiving adjuvant tamoxifen or letrozole in the Breast International Group (BIG) 1-98 trial at 8.7 years of median follow-up....

Breaking of nucleon Cooper pairs at finite temperature in 93-98Mo

International Nuclear Information System (INIS)

Kaneko, K.; Hasegawa, M.; Agvaanluvsan, U.; Algin, E.; Chankova, R.; Guttormsen, M.; Larsen, A. C.; Rekstad, J.; Siem, S.; Mitchell, G. E.; Schiller, A.; Voinov, A.

2006-01-01

The S shape of the canonical heat-capacity curve is known as a signature of the pairing transition, and along an isotopic chain it is significantly more pronounced for nuclei with an even number of neutrons than for those with an odd number. Although the heat capacities extracted from experimental level densities in 93-98 Mo exhibit a clear S shape, they do not show such an odd-even staggering. To understand the underlying physics, we analyze thermal quantities evaluated from the partition function calculated using the static-path plus random-phase approximation (SPA+RPA) in a monopole pairing model with number-parity projection. The calculated level densities reproduce very well the experimental data, and they also agree with estimates made using the back-shifted Fermi-gas model. We clarify the reason why the heat capacities for Mo isotopes do not show odd-even staggering of the S shape. We also discuss thermal odd-even mass differences in 94-97 Mo that were calculated using the three-, four-, and five-point formulas. These thermal mass differences are regarded as indicators of pairing correlations at finite temperature

Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial

DEFF Research Database (Denmark)

Metzger Filho, Otto; Giobbie-Hurder, Anita; Mallon, Elizabeth

2015-01-01

assigned onto the Breast International Group (BIG) 1-98 trial and who had centrally reviewed pathology data were included (N = 2,923). HER2-negative IDC and ILC were additionally classified as hormone receptor-positive with high (luminal B [LB] -like) or low (luminal A [LA] -like) proliferative activity......PURPOSE: To evaluate the relative effectiveness of letrozole compared with tamoxifen for patients with invasive ductal or lobular carcinoma. PATIENTS AND METHODS: Patients diagnosed with early-stage invasive ductal carcinoma (IDC) or classic invasive lobular carcinoma (ILC) who were randomly...

Investigation of various synthetic conditions for large-scale synthesis and electrochemical properties of Li{sub 3.98}Al{sub 0.06}Ti{sub 4.96}O{sub 12}/C as anode material

Energy Technology Data Exchange (ETDEWEB)

Dong, Guo-Hui, E-mail: dgh1516@gmail.com [Shanghai Shanshan Tech Co., Ltd., 3158 Jinhai Road, Shanghai 201209 (China); Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240 (China); Liu, Hua-Jing; Zhou, Liang [Shanghai Shanshan Tech Co., Ltd., 3158 Jinhai Road, Shanghai 201209 (China); Shanghai Second Polytechnic University, 2360 Jinhai Road, Shanghai 201209 (China); Chong, Lina; Yang, Jun [Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240 (China); Qiao, Yong-Min; Zhang, Dian-Hao [Shanghai Shanshan Tech Co., Ltd., 3158 Jinhai Road, Shanghai 201209 (China)

2014-12-05

Graphical abstract: A gel and spray-drying method is demonstrated for large-scale preparation of Li{sub 3.98}Al{sub 0.06}Ti{sub 4.96}O{sub 12}/C secondary microspheres via optimizing various synthetic conditions. The electrochemical performances of the Li{sub 3.98}Al{sub 0.06}Ti{sub 4.96}O{sub 12}/C microspheres are investigated. - Highlights: • Various synthetic conditions are investigated. • Materials can be produced at ∼1 kg scale by using our demonstrated synthesis method. • Li{sub 3.98}Al{sub 0.06}Ti{sub 4.96}O{sub 12}/C sample possesses high electronic conductivity and rate property, and excellent cycling performance. • Secondary micro-spherical Li{sub 3.98}Al{sub 0.06}Ti{sub 4.96}O{sub 12}/C sample has high tap density et al. - Abstract: Poor electronic conductivity is one of the biggest obstacles for practical application of lithium titanate as lithium-ion battery anode material. Utilizing the advantages of coating and doping techniques to optimize the conductive and rate performances of lithium titanate was reported in this work. Herein, the effects of various synthetic conditions including calcination temperatures and holding times, lithium overdoses, carbon contents, doping contents and doping elements on phase, primary particles’ size and electrochemical performance were comprehensively investigated. The optimal Li{sub 3.98}Al{sub 0.06}Ti{sub 4.96}O{sub 12}/C secondary microspheres were synthesized, which possessed high electronic conductivity, tap density, reversible capacity and first columbic efficiency, and excellent rate performances. Furthermore, the synthesized samples were characterized by various techniques.

Residues R199H200 of prototype foamy virus transactivator Bel1 contribute to its binding with LTR and IP promoters but not its nuclear localization

International Nuclear Information System (INIS)

Ma, Qinglin; Tan, Juan; Cui, Xiaoxu; Luo, Di; Yu, Miao; Liang, Chen; Qiao, Wentao

2014-01-01

Prototype foamy virus encodes a transactivator called Bel1 that enhances viral gene transcription and is essential for PFV replication. Nuclear localization of Bel1 has been reported to rely on two proximal basic motifs R 199 H 200 and R 221 R 222 R 223 that likely function together as a bipartite nuclear localization signal. In this study, we report that mutating R 221 R 222 R 223 , but not R 199 H 200 , relocates Bel1 from the nucleus to the cytoplasm, suggesting an essential role for R 221 R 222 R 223 in the nuclear localization of Bel1. Although not affecting the nuclear localization of Bel1, mutating R 199 H 200 disables Bel1 from transactivating PFV promoters. Results of EMSA reveal that the R 199 H 200 residues are vital for the binding of Bel1 to viral promoter DNA. Moreover, mutating R 199 H 200 in Bel1 impairs PFV replication to a much greater extent than mutating R 221 R 222 R 223 . Collectively, our findings suggest that R 199 H 200 directly participate in Bel1 binding to viral promoter DNA and are indispensible for Bel1 transactivation activity. - Highlights: • The R 221 R 222 R 223 residues are essential for the nuclear localization of Bel1. • Although not affecting the nuclear localization of Bel1, mutating R 199 H 200 disables Bel1 from transactivating PFV promoters. • The R 199 H 200 residues directly participate in Bel1 binding to viral promoter DNA. • Mutating R 199 H 200 in Bel1 impairs PFV replication to a much greater extent than mutating R 221 R 222 R 223

Characterization of biological features of a rat F98 GBM model: A PET-MRI study with [18F]FAZA and [18F]FDG

International Nuclear Information System (INIS)

Belloli, Sara; Brioschi, Andrea; Politi, Letterio Salvatore; Ronchetti, Francesca; Calderoni, Sara; Raccagni, Isabella; Pagani, Antonella; Monterisi, Cristina; Zenga, Francesco; Zara, Gianpaolo; Fazio, Ferruccio; Mauro, Alessandro

2013-01-01

Introduction: The prognosis of malignant gliomas remains largely unsatisfactory for the intrinsic characteristics of the pathology and for the delayed diagnosis. Multimodal imaging based on PET and MRI may assess the dynamics of disease onset and progression allowing the validation of preclinical models of glioblastoma multiforme (GBM). The aim of this study was the characterization of a syngeneic rat model of GBM using combined in vivo imaging and immunohistochemistry. Methods: Four groups of Fischer rats were implanted in a subcortical region with increasing concentration of rat glioma F98 cells and weekly monitored with Gd-MR, [ 18 F]FDG- and [ 18 F]FAZA-PET starting one week after surgery. Different targets were evaluated on post mortem brain specimens using immunohistochemistry: VEGF, GFAP, HIF-1α, Ki-67 and nestin. Results: Imaging results indicated that tumor onset but not progression was related to the number of F98 cells. Hypoxic regions identified with [ 18 F]FAZA and high-glucose metabolism regions recognized with [ 18 F]FDG were located respectively in the core and in external areas of the tumor, with partial overlap and remodeling during disease progression. Histological and immunohistochemical analysis confirmed PET/MRI results and revealed that our model resumes biological characteristics of human GBM. IHC and PET studies showed that necrotic regions, defined on the basis of [ 18 F]FDG uptake reduction, may include hypoxic clusters of vital tumor tissue identified with [ 18 F]FAZA. This last information is particularly relevant for the identification of the target volume during image-guided radiotherapy. Conclusions: In conclusion, the combined use of PET and MRI allows in vivo monitoring of the biological modification of F98 lesions during tumor progression

"Belõje slonõ" gotovõ k razdatshe / Viktor Matizen

Index Scriptorium Estoniae

Matizen, Viktor

2006-01-01

Venemaa filmikriitikute auhinna "Zolotoi Oven" asemel jagatakse sel aastal esmakordselt Ivan Maksimovi poolt modelleeritud "Valgeid Elevante" ("Belõi slon"). Vene filmikriitikute gildi president selle aasta nominentidest. Lisa : nimekiri "Nominandid preemiale "Valge Elevant" -2005"

Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial

DEFF Research Database (Denmark)

Rabaglio, M; Sun, Z; Price, K N

2009-01-01

of letrozole or tamoxifen in the BIG 1-98 trial who received at least some study medication (median follow-up 60.3 months). Bone fracture information (grade, cause, site) was collected every 6 months during trial treatment. RESULTS: The incidence of bone fractures was higher among patients treated......BACKGROUND: To compare the incidence and timing of bone fractures in postmenopausal women treated with 5 years of adjuvant tamoxifen or letrozole for endocrine-responsive early breast cancer in the Breast International Group (BIG) 1-98 trial. METHODS: We evaluated 4895 patients allocated to 5 years...... with letrozole [228 of 2448 women (9.3%)] versus tamoxifen [160 of 2447 women (6.5%)]. The wrist was the most common site of fracture in both treatment groups. Statistically significant risk factors for bone fractures during treatment included age, smoking history, osteoporosis at baseline, previous bone...

Coal -98

International Nuclear Information System (INIS)

Sparre, C.

1998-01-01

Energi, Haesselbyverket, has now invested in equipment for burning pellets instead of coal. In Linkoeping wastes of rubber are mixed with coal. Also Soederenergi AB has rebuilt their three coal boilers and replaced 100 % of the coal by peat and wood fuels. Coal is a reserve fuel. Several co-generation plants like Linkoeping, Norrkoeping, Uppsala and Oerebro use both coal and forest fuels. The use of coal is then concentrated to the electricity production. The average price of steam coal imported in Sweden in 1997 was 370 SEK/ton or 10 per cent higher than in 1996. For the world, the average import price fell to 46 USD/ton. The price fall was concentrated to the 4th quarter. The prices have continued to fall during 1998 as a result of the crisis in Asia. All Swedish plants meet their emission limits of dust, SO 2 and NO x given by county administrations or concession boards. The co-generation plants have all some sort of SO 2 -removal system. Mostly used is the wet-dry method. The biggest co-generation plant, Vaesteraas, has newly invested in a ca talytic NO x -cleaning system type SCR, which is reducing the emission level 80-90 %. Most other plants are using low NO x -burners or injection systems type SNCR, based on ammonium or urea, which are reducing the emissions 50-70 %. A positive effect of the recently introduced NO x -duties is a 60 % reduction compared to some years ago, when the duties were introduced. World hard coal production was about 3 800 tons in 1997, a minor increase compared to 1996. The coal demand in the OECD-countries has increased about 1.7 % yearly during the last ten years. The coal share of the energy supply is about 20% in the OECD-countries and 27% in the whole world. Several sources estimate a continuing growth during the next 20 years in spite of an increasing use of natural gas and nuclear power. The reason is a strong demand for electrical power in the Asian countries and the developing countries. However, greater efforts to minimize the

High performance zero-bleed CLSM/grout mixes for high-level waste tank closures strategic research and development - FY98

International Nuclear Information System (INIS)

Langton, C.A.

2000-01-01

The overall objective of this program, SRD-98-08, is to design and test suitable materials, which can be used to close high-level waste tanks at the Savannah River Site. Fill materials can be designed to perform several functions. They can be designed to chemically stabilize and/or physically encapsulate incidental waste so that the potential for transport of contaminants into the environment is reduced. Also they are needed to physically stabilize the void volume in the tanks to prevent/minimize future subsidence and inadvertent intrusion

High performance zero-bleed CLSM/grout mixes for high-level waste tank closures strategic research and development - FY98

Energy Technology Data Exchange (ETDEWEB)

Langton, C.A.

2000-02-17

The overall objective of this program, SRD-98-08, is to design and test suitable materials, which can be used to close high-level waste tanks at the Savannah River Site. Fill materials can be designed to perform several functions. They can be designed to chemically stabilize and/or physically encapsulate incidental waste so that the potential for transport of contaminants into the environment is reduced. Also they are needed to physically stabilize the void volume in the tanks to prevent/minimize future subsidence and inadvertent intrusion.

The Relationship between Waiting Times and "Adherence" to the Scottish Intercollegiate Guidelines Network 98 Guideline in Autism Spectrum Disorder Diagnostic Services in Scotland

Science.gov (United States)

McKenzie, Karen; Forsyth, Kirsty; O'Hare, Anne; McClure, Iain; Rutherford, Marion; Murray, Aja; Irvine, Linda

2016-01-01

The aim of this study was to explore the extent to which the Scottish Intercollegiate Guidelines Network 98 guidelines on the assessment and diagnosis of autism spectrum disorder were adhered to in child autism spectrum disorder diagnostic services in Scotland and whether there was a significant relationship between routine practice which more…

Demonstration of site-dependent dynamics of ozone effects in tobacco (Nicotina tabacum L. Bel W3) in Greater Rostock; Nachweis einer standoertlich differenzierten Dynamik der Ozonwirkung an Tabak (Nicotina tabacum L. Bel W3) im Grossraum Rostock

Energy Technology Data Exchange (ETDEWEB)

Odya, S.; Stuedemann, O.; Eckert, S. [Rostock Univ. (Germany). Inst. fuer Landschaftsplanung und Landschaftsoekologie

1999-07-01

The goal of the present study was to describe the genesis of a geographic pattern of phytotoxic ozone effects in the case of a mesoscale climate sequence. For this purpose the ''Applied Meteorology and Climatology'' working group carried out an active biomonitoring field trial with different bioindicator plants (Nicotina Tabacum L. Bel W3 and Bel B, bush bean, darnel, wheat and common nettle) over 4 vegetation periods. The trial was designed on the basis of existing knowledge on the spatially heterogeneous occurrence of ozone episodes and site-dependent phytotoxic ozone effects. [German] Das Ziel unserer Untersuchungen ist die Beschreibung der Genese des geographischen Musters phytotoxischer Ozonwirkungen im Bereich einer mesoskalen Klimasequenz in Nordost-Deutschland. Dazu wurde in Kenntnis des arealheterogenen Auftretens der Ozonepisoden und der standortabhaengigen phytotoxischen Ozonwirkung von der AG 'Angewandte Meteorologie und Klimatologie' ein aktives Biomonitoring mit verschiedenen Bioindikatorpflanzen (Nicotiana tabacum L. Bel W3 und Bel B, Buschbohne, Weidelgras, Weizen, Grosse Brennessel) ueber 4 Vegetationsperioden (1995-1998) im Freiland durchgefuehrt. (orig.)

DEWEK '98: 4. German wind power conference; DEWEK '98: 4. Deutsche Windenergie-Konferenz. Tagungsband

Energy Technology Data Exchange (ETDEWEB)

Gerdes, B. [ed.

1999-07-01

The conference report comprises 90 papers and posters on the following subjects: 1. Technological developments (e.g. use of adaptive structures systems, active stalle wind power systems, systems for early detection of errors); 2. Design and optimisation; 3. Wind forecasts; 4. Operation analyses (e.g. active and passive stall, collective loads, wind power systems in cold climates); 5. Wind power systems and the environment; 6. Offshore wind power generation; 7. Electric characteristics (e.g. modelling of flicker, energy conditioning in distribution systems with a high wind power share); 8. Economic efficiency (e.g. economic efficiency of offshore wind parks on the North Sea coast); 9. Network quality; 10. Rotor development (e.g. noise reduction); 11. Certification and methods of measurement. [German] Der Tagungsband enhaelt 90 Fach- und Posterbeitraege, die sich mit den folgenden Schwerpunkten befassen: 1. Technologische Entwicklungen (z.B. Einsatz von adaptiven Struktursystemen; Active-Stall-WKA; Fehlerfrueherkennungssystemen). 2. Auslegung und Optimierung. 3. Windprognosen. 4. Betriebsanalysen (z.B. Aktive Stall/Passive Stall im Vergleich; Lastkollektive von WKA; WKA in kaltem Klima). 5. Windenergieanlagen und Umwelt. 6. Offshore-Windenergienutzung. 7. Elektrische Eigenschaften (z.B. Modellierung des 'Flickerverhaltens' von WKA; Energiekonditionierung in Verteilnetzen mit hohem Windenergieanteil). 8. Wirtschaftlichkeit (z.B. Wirtschaftlichkeit von Offshore-Windparks der Norddeutschen Kuestenlinie). 9. Netzqualitaet. 10. Rotorentwicklung (z.B. Reduzierung der Schallabstrahlung von WKAs). 11. Zertifizierung von Messmethoden. (AKF)

Mutagenic and antimutagenic activities of Artemisia absinthium volatile oil by the bacterial reverse mutation assay in Salmonella typhimurium strains TA98 and TA100

Directory of Open Access Journals (Sweden)

Mahboubeh Taherkhani

2014-09-01

Full Text Available Objective: To investigate the mutagenic and antimutagenic activities of Artemisia absinthium L. (A. absinthium essential oil by the bacterial reverse mutation assay in Salmonella typhimurium (S. typhimurium strains. Methods: Water-distilled essential oil of A. absinthium collected from Ardabil, NorthWestern Iran, was investigated for mutagenic and antimutagenic activities. In present study, the mutagenic and antimutagenic activities of A. absinthium oil were investigated by the bacterial revere mutation assay in S. typhimurium TA98 and TA100 strains with and without S9 (microsomal mutagenesis assay. Results: The comparative mutagenicity effect was seen in 1.5 mg/plate by the bacterial reverse mutation assay in S. typhimurium TA98 strains, without S9 and the excellent antimutagenicity effect was seen in 1.5 mg/plate against S. typhimurium TA100, without S9. Conclusions: The mutagenicity and antimutagenicity effects of the volatile oil of A. absinthium were seen without the presence of metabolic activation.

The tropospheric aerosol at mid-latitudes - microphysics, optics, and climate forcing illustrated by the LACE 98 field study; Das troposphaerische Aerosol in mittleren Breiten - Mikrophysik, Optik und Klimaantrieb am Beispiel der Feldstudie LACE 98

Energy Technology Data Exchange (ETDEWEB)

Fiebig, M.

2001-07-01

This study investigates the column closure of optical aerosol parameters as part of the Lindenberg Aerosol Characterisation Experiment (LACE 98). The optical aerosol parameters were calculated from microphysical aerosol parameters which were measured height resolved from tropopause to boundary layer and compared with the direct measurement of the respective property (closure). The closure allows the validation of the measured aerosol properties and the inversion of aerosol properties which are not measurable directly. The radiative forcings of the measured aerosol columns are estimated. The measured, quality assured microphysical aerosol properties are parameterized and tabulated as input data for models. The successful closure of the aerosol column's optical depth validates the measured particle size distributions, whereas the successful closure of the backscatter coefficient validates the assumptions made on the aerosol chemical composition and serves to deduce its state of mixture, the latter point exemplified using a 7 day old forest fire aerosol. The local, instantaneous radiative forcing of the measured continental particle columns are estimated to lie between -33 W/m{sup 2} for continental and -6 W/m{sup 2} for marine air masses for a solar zenith angle of 56 . (orig.) [German] Als Teil des Lindenberger Aerosol Charakterisierungsexperimentes (LACE 98) behandelt diese Arbeit die Saeulenschliessung optischer Aerosolparameter. Diese wurden aus den von Tropopause bis Grenzschicht hoehenaufgeloest gemessenen mikrophysikalischen Aerosoleigenschaften berechnet, um sie mit den am gleichen Ort direkt gemessenen optischen Aerosolparametern zu vergleichen (Schliessung). Es wird gezeigt, dass die Schliessung die Qualitaetssicherung der gemessenen Aerosoleigenschaften und die Invertierung direkt nicht messbarer Aerosoleigenschaften ermoeglicht. Die Strahlungsantriebe der vermessenen Aerosolsaeulen werden abgeschaetzt. Die qualitaetsgesicherten gemessenen

Neutralizing Antibodies to Enterovirus 71 in Belém, Brazil

Directory of Open Access Journals (Sweden)

Maria de Lourdes C Gomes

2002-01-01

Full Text Available Non-polio enteroviruses (Coxsackievirus A, Coxsackievirus B, Echovirus and EV 68-72 which belong to the enterovirus (EV genus, Picornaviridae family, may be responsible for acute flaccid paralysis, aseptic meningitis, myocarditis, hepatitis, pleurodinia, neonatal sepsis, hand, foot and mouth disease (HFMD even though 50-80% of infections are asymptomatic. EV 71 has been responsible for outbreaks and epidemics of HFMD and acute neurologic disease justifying its study in our country. The aim of this study was to detect neutralizing antibodies (NtAb to EV 71 in individuals up to 15 years of age living in Belém, State of Pará, northern Brazil. Serum samples from 238 patients attending the Virology Sector of Evandro Chagas Institute in Belém, Brazil, were analyzed using microneutralization tests that included RD cells and BrCr strain. Overall 40.8% (97/238 of tested samples had NtAb to EV 71. Regarding the distribution per age group, 85.2% (92/108 of patients aged 0-3 years had no NtAb to this virus and 69.2% of those 12 to15 years of age were seropositive. These results confirm that EV 71 infection occurs in the city of Belém; and that a high rate of individuals in this study were infected aged 3 years and over and, when aged 15 years nearly 70% had EV 71 NtAb.

Tratamento de resíduo líquido de laticínios utilizando Caixas de Gordura e Reator Anaeróbio Compartimentado seguido de Leitos Cultivados

Directory of Open Access Journals (Sweden)

Ana Cristina Ferreira Moreira da Silva

2014-10-01

Full Text Available Neste trabalho foram avaliados o desempenho e a eficiência de um sistema de tratamento de resíduos líquidos de laticínios na remoção da carga orgânica do resíduo em uma indústria de laticínios, utilizando um sistema composto por caixas de gordura, reator anaeróbio compartimentado e leitos cultivados de fluxo subsuperficial vegetado com Typha sp. e utilizando como meio suporte brita #1, sob diferentes tempos de detenção hidráulica (3 e 5 dias nos leitos cultivados. Como média geral na remoção de DBO e de DQO, o tratamento utilizando tempo de detenção de 3 dias conseguiu remover 98,87% de DBO e  99,77% de DQO, enquanto o tratamento utilizando 5 dias de detenção hidráulica removeu, em média, 99,51% de DBO e 99,56% de DQO. Os resultados indicam que o sistema foi eficiente no tratamento de resíduos líquidos de laticínios.

Dapnia 97-98; Dapnia 97-98

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

Fundamental research is by essence without limits and should not be thwarted by interdisciplinary barriers. DAPNIA, Department of Astrophysics, Particle physics, Nuclear Physics and Associated Instrumentation, was created in 1991, as part of the Directorate of Matter Science (DSM), to encourage symbiosis between astrophysics, particle physics and nuclear physics and to pool the resources of technical support groups. DAPNIA has a unique multidisciplinary structure which has promoted the development of experiments at the borderlines between different fields of research and which favours necessary new directions in research and selection of the most promising programmes. Research in DAPNIA is always performed within national or international collaborations while taking advantage of other CEA department's expertise. Research teams of DAPNIA, IN{sub 2}P{sub 3} (Institut National de Physique Nucleaire et de Physique des Particules) and INSU (Institut National des Sciences de l'Univers), working together within large international collaborations, reinforce their contributions through their specific competencies. The CERN laboratory is a privileged partner in particle physics and hadronic physics. All our space experiments are co-financed by the CNES (Centre National d'Etudes Spatiales). This booklet presents the organisation of DAPNIA in ten services and lists all the experiments and instrumental developments for 1977 and 1998 in the form of summary sheets. The list of projects in pictured on the inner cover of the booklet and shows smooth transitions between all fields of research, from the study of the most elementary components of matter to the largest structures in the Universe. (authors)

Dapnia 97-98; Dapnia 97-98

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

Fundamental research is by essence without limits and should not be thwarted by interdisciplinary barriers. DAPNIA, Department of Astrophysics, Particle physics, Nuclear Physics and Associated Instrumentation, was created in 1991, as part of the Directorate of Matter Science (DSM), to encourage symbiosis between astrophysics, particle physics and nuclear physics and to pool the resources of technical support groups. DAPNIA has a unique multidisciplinary structure which has promoted the development of experiments at the borderlines between different fields of research and which favours necessary new directions in research and selection of the most promising programmes. Research in DAPNIA is always performed within national or international collaborations while taking advantage of other CEA department's expertise. Research teams of DAPNIA, IN{sub 2}P{sub 3} (Institut National de Physique Nucleaire et de Physique des Particules) and INSU (Institut National des Sciences de l'Univers), working together within large international collaborations, reinforce their contributions through their specific competencies. The CERN laboratory is a privileged partner in particle physics and hadronic physics. All our space experiments are co-financed by the CNES (Centre National d'Etudes Spatiales). This booklet presents the organisation of DAPNIA in ten services and lists all the experiments and instrumental developments for 1977 and 1998 in the form of summary sheets. The list of projects in pictured on the inner cover of the booklet and shows smooth transitions between all fields of research, from the study of the most elementary components of matter to the largest structures in the Universe. (authors)

Treatment Adherence and Its Impact on Disease-Free Survival in the Breast International Group 1-98 Trial of Tamoxifen and Letrozole, Alone and in Sequence

DEFF Research Database (Denmark)

Chirgwin, Jacquie H; Giobbie-Hurder, Anita; Coates, Alan S

2016-01-01

PURPOSE: To investigate adherence to endocrine treatment and its relationship with disease-free survival (DFS) in the Breast International Group (BIG) 1-98 clinical trial. METHODS: The BIG 1-98 trial is a double-blind trial that randomly assigned 6,193 postmenopausal women with hormone receptor......-positive early breast cancer in the four-arm option to 5 years of tamoxifen (Tam), letrozole (Let), or the agents in sequence (Let-Tam, Tam-Let). This analysis included 6,144 women who received at least one dose of study treatment. Conditional landmark analyses and marginal structural Cox proportional hazards......). Sequential treatments were associated with higher rates of nonpersistence (Tam-Let, 20.8%; Let-Tam, 20.3%; Tam 16.9%; Let 17.6%). Adverse events were the reason for most trial treatment early discontinuations (82.7%). Apart from sequential treatment assignment, reduced adherence was associated with older age...

"El Niño 1997-98": su efecto sobre el ambiente y los recursos pesqueros en el Perú

Directory of Open Access Journals (Sweden)

Marco Espino

2014-06-01

Full Text Available Se presenta una reseña de los efectos del fenómeno "El Niño 1997-98" en los recursos pesqueros del ecosistema de afloramiento peruano, dando especial énfasis a los cambios en los patrones de distribución y abundancia de los recursos anchoveta, sardina y merluza; ya los cambios en la autoecología de los mismos recursos. Finalmente, se comenta sobre las similitudes y diferencias de los efectos de este fenómeno con otros eventos de la misma naturaleza.

Wright-Patterson AFB, Ohio Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

Science.gov (United States)

1985-09-01

LSTI: ISO -1700 ............. [..........................................NO" ........". OT5...................................................... I WIND...90.3 91.1 91.3 91.4 91.6 92.6 91.b 9i.T 91.7 91.7 91.7 E iso 51.i8 - 76.9 82.1 8b. 90.7 90.7 92.s 92.7 92.8 93.0 93.0 93.0 93.1 93.1 93.1 93.1 FE 2000...97.4 91.4 97.% 91.4 97.4 GE 27003 55.1 79.4 84.4 90.1 95.7 96.8 97.1 98.0 88.1 98.1 98.1 98.1 91.3 98.1 98.1 98.1 UE 18001 55.1 79.5 84.5 90.? 95.8 96.9

The Swedish Nuclear Power Inspectorate's evaluation of SKB's RD and D Program 98. Review report

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-04-01

According to the Act (1984:3) on Nuclear Activities, the full responsibility for the safe management and final disposal of spent nuclear fuel and nuclear waste rests with the owners of the Swedish nuclear power reactors. In accordance with the Act (1992:1537) on the Financing of Future Expenses for Spent Nuclear Fuel etc., the owners are also responsible for ensuring that funds are set aside to cover the future expenses of the management and final disposal of spent nuclear fuel and nuclear waste. Furthermore, nuclear reactor owners must conduct, and every three years, submit a research and development programme for the management of the spent nuclear fuel and nuclear waste. The programme must also cover the measures which are necessary for the decommissioning and dismantling of the nuclear installations. SKI must submit the programme documents to the Government, along with its own statement. The owners of the nuclear power reactors have formed a joint company, SKB which, on behalf of the owners, fulfils the owners' statutory obligations with respect to the management and final disposal of spent nuclear fuel and nuclear waste and conducts related research and development. The programme now submitted by SKB is the latest in the series which started with RandD Programme 86. The current programme was submitted in September 1998 and is called RDandD Programme 98 (programme for Research, Development and Demonstration). In RDandD Programme 98, SKB has stated that it particularly welcomes viewpoints concerning: Whether deep disposal according to the KBS-3 method will continue to be the preferred method. The body of material that SKB is compiling in preparation for the selection of sites for site investigation. What is to be included in future Environmental Impact Statements (EIS). Compared to previous programmes, RDandD Programme 98 is focused to a greater extent on method and site selection and on issues relating to the decision-making process. In order to emphasise

Survival Analysis of F98 Glioma Rat Cells Following Minibeam or Broad-Beam Synchrotron Radiation Therapy

International Nuclear Information System (INIS)

Gil, Silvia; Sarun, Sukhéna; Biete, Albert; Prezado, Yolanda; Sabés, Manel

2011-01-01

In the quest of a curative radiotherapy treatment for gliomas new delivery modes are being explored. At the Biomedical Beamline of the European Synchrotron Radiation Facility (ESRF), a new spatially-fractionated technique, called Minibeam Radiation Therapy (MBRT) is under development. The aim of this work is to compare the effectiveness of MBRT and broad-beam (BB) synchrotron radiation to treat F98 glioma rat cells. A dose escalation study was performed in order to delimit the range of doses where a therapeutic effect could be expected. These results will help in the design and optimization of the forthcoming in vivo studies at the ESRF. Two hundred thousand F98 cells were seeded per well in 24-well plates, and incubated for 48 hours before being irradiated with spatially fractionated and seamless synchrotron x-rays at several doses. The percentage of each cell population (alive, early apoptotic and dead cells, where either late apoptotic as necrotic cells are included) was assessed by flow cytometry 48 hours after irradiation, whereas the metabolic activity of surviving cells was analyzed on days 3, 4, and 9 post-irradiation by using QBlue test. The endpoint (or threshold dose from which an important enhancement in the effectiveness of both radiation treatments is achieved) obtained by flow cytometry could be established just before 12 Gy in the two irradiation schemes, whilst the endpoints assessed by the QBlue reagent, taking into account the cell recovery, were set around 18 Gy in both cases. In addition, flow cytometric analysis pointed at a larger effectiveness for minibeams, due to the higher proportion of early apoptotic cells. When the valley doses in MBRT equal the dose deposited in the BB scheme, similar cell survival ratio and cell recovery were observed. However, a significant increase in the number of early apoptotic cells were found 48 hours after the minibeam radiation in comparison with the seamless mode

Law no 2006/18 of June 21, 2006 modifying the law no 98-011 of May 7, 1998 providing for the creation of a Public Establishment of the executive power named the National Radioprotection Center (CNRP)

International Nuclear Information System (INIS)

2006-01-01

This law provides for the modification of articles 2 and 5 of the law 98-011 of 07 May 98 providing for the creation of National Radiation Protection Centre (CNRP). CNRP is the National Regulatory Authority in Nuclear Security Safety and Safeguards and in Radiation protection. It is member of the Technical consultative committee for radioprotection and nuclear technics [fr

COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

International Nuclear Information System (INIS)

Skliarov, V.; Rottger, A.; Honig, A.; Korostin, S.; Kuznetsov, S.; Lapenas, A.; Milevsky, V.; Ivaniukovich, A.; Kharitonov, I.; Sepman, S.

2009-01-01

According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5. meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. (authors)

COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

Energy Technology Data Exchange (ETDEWEB)

Skliarov, V. [National Scientific Centre, Institute of Metrology (NSC IM), Kharkiv (Ukraine); Rottger, A.; Honig, A. [Physikalisch-Technische Bundesanstalt (PTB), Braunschweig (Germany); Korostin, S.; Kuznetsov, S. [All-Russian Scientific Research Institute of Physical, Technical and Radio Measurements (VNIIFTRI), Moscow Region, Mendeleyevo (Russian Federation); Lapenas, A. [Latvian National Metrology Centre Ltd, Radiation Metrology and Testing Centre (RMTC), Salaspils (Latvia); Milevsky, V.; Ivaniukovich, A. [Belarussian State Institute of Metrology (BelGIM), Minsk (Belarus); Kharitonov, I.; Sepman, S. [D I Mendeleyev Institute of metrology (VNIIM), Saint Petersburg (Russian Federation)

2009-06-15

According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5. meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. (authors)

Annual International Conference of the German Operations Research Society (GOR) University of Augsburg

CERN Document Server

Borgwardt, Karl-Heinz; Klein, Robert; Tuma, Axel

2009-01-01

This book contains 93 selected papers from the symposium "Operations Research 2008" which was held from September 3-5, 2008 at the University of Augsburg, Germany. The international conference, which also serves as the annual meeting of the German Operations Research Society (GOR), attracted 580 participants from more than thirty countries. The general theme "Operations Research and Global Business" stresses the important role of Operations Research in improving decisions in the increasingly complex global business environment. Operations Research represents one of the most successful instruments for organizing business processes, as many applications in areas like supply chain management or financial management show. The book gives a broad overview of the various facets of Operations Research: mathematical methods such as optimization, forecasting, data analysis or game theory and their applications in business, economics and social life.

Istemööbel Sheff = Sheff : modular seating furniture

Index Scriptorium Estoniae

2008-01-01

Standardi istemööbel Sheff. Ühe laia käetoega tugitoole saab ühendada diivaniks, moodustada neist gruppe. Tugitoole täiendavad vaheplaadid, mis liidetuna tooli käetoega moodustavad lauakese. Disainer Katrin Soans, tema tähtsamad tööd. 2 värv. vaadet, foto K. Soansist

The year-wise nodulation behavior and biological nitrogen fixation parameters of chickpea (cicer aritinum, L) at some selected sites in the southern zone of Pakistan during 1995-98

International Nuclear Information System (INIS)

Idris, M.

2000-01-01

Study was carried out during 1995-98 to know the location and year-wise nodulation response (number and weight of nodules/plant) and the related biological nitrogen fixation parameters (dry matter yield, n concentration and yield/plant) of the crop at some selected sites ( Peshawar, Kohat, Krak, Bannu and D. I. Khan ) under the agro climatic conditions prevailing in the southern zones of NWFP-Pakistan. The crop was found to be profusely nodulating under the agro climatic conditions prevailing at all sites except at Barani-Agricultural Research station (bars) Kohat, where the nodulation of the crop almost remained inclined to be nil. The nodulation behavior and biological nitrogen fixation parameters of chickpea during 1995-98 in the southern zone of NWFP- Pakistan has been described. (author)

Single hole spectroscopic strength in 98Ru through the 99Ru(d,t) reaction

International Nuclear Information System (INIS)

Rodrigues, M.R.D.; Borello-Lewin, T.; Horodynski-Matsushigue, L.B.; Duarte, J.L.M.; Rodrigues, C.L.; Barbosa, M.D.L.; Silva, G.B. da; Ukita, G.M.

2002-01-01

The 99 Ru(d,t) 98 Ru reaction was measured for the first time at 16 MeV incident energy with the Sao Paulo Pelletron-Enge-spectrograph facility employing the nuclear emulsion technique. In all, up to 3.5 MeV, 23 levels were detected, eight of them new; angular distributions are presented for all of them. Least squares fits of distorted wave Born approximation one-neutron pickup predictions to the rather well structured experimental angular distributions enabled the determination of l transfers and of the corresponding spectroscopic factors for 19 of these states, some being tentative attributions. Only transfers of l=0, 2, and 4 were observed. Several states were populated through single l transfers. A pure l=2 transfer is associated with the 2 1 + level and with several other states which are considered collective, as well as with the (4 + ) state at 2.277 MeV, which presents the highest spectroscopic strength. Considering five valence neutrons above the N=50 core, only 41% of the spectroscopic strength expected for 99 Ru was detected

Sr{sub 1.98}Eu{sub 0.02}SiO{sub 4} luminescence whisker based on vapor-phase deposition: Facile synthesis, uniform morphology and enhanced luminescence properties

Energy Technology Data Exchange (ETDEWEB)

Xu, Jian, E-mail: xujian@stu.xmu.edu.cn [Department of Materials Science and Engineering, Xiamen University, Xiamen 361005 (China); Hassan, Dhia A. [Department of Materials Science and Engineering, Xiamen University, Xiamen 361005 (China); Department of Chemistry, College of Education for Pure Science, University of Basrah, 61004 (Iraq); Zeng, Renjie; Peng, Dongliang [Department of Materials Science and Engineering, Xiamen University, Xiamen 361005 (China); Fujian Key Lab of Advanced Special Material, Xiamen University, Xiamen 361005 (China); Key Laboratory of High Performance Ceramic Fibers, Ministry of Education, Xiamen 361005 (China)

2015-11-15

Highlights: • For the first time, it is possible to obtain Sr{sub 1.98}Eu{sub 0.02}SiO{sub 4} whisker. • The whiskers are smooth and uniform with L/D ratio over 50. • Durability and thermal stability of the whisker are enhanced. - Abstract: A high performance strontium silicate phosphor has been successfully synthesized though a facile vapor-phase deposition method. The product consists of single crystal whiskers which are smooth and uniform, and with a sectional equivalent diameter of around 5 μm; the aspect ratio is over 50 and no agglomeration can be observed. X-ray diffraction result confirmed that the crystal structure of the whisker was α’-Sr{sub 2}SiO{sub 4}. The exact chemical composition was Sr{sub 1.98}Eu{sub 0.02}SiO{sub 4} which was analyzed by energy dispersive spectrometer and inductively coupled plasma-mass spectrometer. The whisker shows broad green emission with peak at 523 nm ranging from 470 to 600 nm (excited at 370 nm). Compared with traditional Sr{sub 2}SiO{sub 4}:Eu phosphor, durability (at 85% humidity and 85 °C) and thermal stability of the whisker are obviously improved. Moreover, growth mechanism of the Sr{sub 1.98}Eu{sub 0.02}SiO{sub 4} whiskers is Vapor–Liquid–Solid. On a macro-scale, the product is still powder which makes it suitable for the current packaging process of WLEDs.

Condiciones meteorológicas a nivel global y local, cambio climático y "El Niño 1997-98"

Directory of Open Access Journals (Sweden)

Ena Jaimes

2014-06-01

Full Text Available El evento "El Niño 1997-98" mostró una evolución rápida y de gran intensidad, resultando uno de los más fuertes ocurridos sobre el Pacífico Ecuatorial Central y Oriental en los últimos 150 años. En la costa peruana el calentamiento del agua de mar inducido por "El Niño 1997-98" empezó en marzo de 1997, con la incursión de aguas subtropicales y ecuatoriales. Las condiciones atmosféricas y oceánicas a macroescala se mantuvieron y alcanzaron su máxima intensidad en noviembre y diciembre de 1997. La Zona de Convergencia Intertropical estuvo desplazada al sur de su posición normal, en gran parte del año 1997. "El Niño" afectó el clima del país desde inicios del otoño de 1997. El invierno resultó uno de los más cálidos de la historia peruana, con anomalías que alcanzaron hasta los 6°C en la costa central. Asimismo, se registraron caídas de presión atmosférica en el Pacífico Oriental; lluvias que superaron significativamente sus promedios en la parte media y alta de la costa norte del Perú; y lluvias normales o ligeramente deficientes en la sierra, particularmente en el sur del país.

Transcriptomic Profiling Reveals Complex Molecular Regulation in Cotton Genic Male Sterile Mutant Yu98-8A.

Directory of Open Access Journals (Sweden)

Weiping Fang

Full Text Available Although cotton genic male sterility (GMS plays an important role in the utilization of hybrid vigor, its precise molecular mechanism remains unclear. To characterize the molecular events of pollen abortion, transcriptome analysis, combined with histological observations, was conducted in the cotton GMS line, Yu98-8A. A total of 2,412 genes were identified as significant differentially expressed genes (DEGs before and during the critical pollen abortion stages. Bioinformatics and biochemical analysis showed that the DEGs mainly associated with sugars and starch metabolism, oxidative phosphorylation, and plant endogenous hormones play a critical and complicated role in pollen abortion. These findings extend a better understanding of the molecular events involved in the regulation of pollen abortion in genic male sterile cotton, which may provide a foundation for further research studies on cotton heterosis breeding.

Controle de mosca doméstica em área de disposição de resíduos sólidos no Brasil House fly control in solid waste disposal area in Brazil

Directory of Open Access Journals (Sweden)

Adair Ferreira Motta Teixeira

2008-12-01

Full Text Available Desenvolveu-se uma metodologia de controle de Musca domestica (L. em áreas de disposição de resíduos sólidos. Dois mosquicidas à base de azametifós foram aplicados em diferentes superfícies: nas verticais, a formulação pó molhável foi aplicada com rolos de pintura e, através de pulverização, na superfície de leiras; nas horizontais, foi empregado o mosquicida na formulação granulada. O nível de infestação de moscas foi avaliado por meio do monitoramento em placas (Scudder Fly Grill. Nas áreas das leiras, reduções de 98,5% e 100% foram atingidas em 18 e 30 dias, respectivamente, após a aplicação do produto. Na estação de transferência do lixo, observaram-se reduções de 85,6% e 98,7% no mesmo período de tempo. A aplicação de azametifós em diferentes formulações mostrou ser eficiente no controle da Musca domestica por um período de 30 dias.A Musca domestica (L. control method in solid waste disposal areas was developed. Two fly control products based on azamethiphos were applied to different surfaces: on vertical surfaces, the wettable powder was used as spray or paint-on and on windrows, as spray; on horizontal surfaces granular bait was used. Fly infestation was evaluated by Scudder Fly Grills. In the windrows areas, reductions of 98,5% and 100 % were achieved 18 and 30 days respectively after application. In the waste transfer station 85,6% and 98,7 % reductions were achieved over the same period of time. Application of azamethiphos in different formulations was effective against M. domestica for 30 days.

Post-Closure Monitoring Report for Corrective Action Unit 98, Frenchman Flat, Underground Test Area, Nevada National Security Site, Nevada for Calendar Year 2016 (January 2016–December 2016), Revision 0

Energy Technology Data Exchange (ETDEWEB)

Farnham, Irene [Navarro, Las Vegas, NV (United States)

2017-06-01

Corrective Action Unit (CAU) 98: Frenchman Flat on the Nevada National Security Site was the location of 10 underground nuclear tests. CAU 98 underwent a series of investigations and actions in accordance with the Federal Facility Agreement and Consent Order to assess contamination of groundwater by radionuclides from the tests. A Closure Report completed that process in 2016 and called for long-term monitoring, use restrictions (URs), and institutional controls to protect the public and environment from potential exposure to contaminated groundwater. Three types of monitoring are performed for CAU 98: water quality, water level, and institutional control. These are evaluated to determine whether the UR boundaries remain protective of human health and the environment, and to ensure that the regulatory boundary objectives are being met. Additionally, monitoring data are used to evaluate consistency with the groundwater flow and contaminant transport models because the contaminant boundaries (CBs) calculated with the models are the primary basis of the UR boundaries. In summary, the monitoring results from 2016 indicate the regulatory controls on the closure of CAU 98 remain effective in protection of human health and the environment. Recommendations resulting from this first year of monitoring activities include formally incorporating wells UE-5 PW-1, UE-5 PW-2, and UE-5 PW-3 into the groundwater-level monitoring network given their strategic location in the basin; and early development of a basis for trigger levels for the groundwater-level monitoring given the observed trends. Additionally, it is recommended to improve the Real Estate/Operations Permit process for capturing information important for evaluating the impact of activities on groundwater resources, and to shift the reporting requirement for this annual report from the second quarter of the federal fiscal year (end of March) to the second quarter of the calendar year (end of June).

Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial

DEFF Research Database (Denmark)

Regan, M.M.; Lykkesfeldt, A.E.; Dell'Orto, P.

2008-01-01

Background The Breast International Group (BIG) 1-98 trial (a randomised double-blind phase III trial) has shown that letrozole significantly improves disease-free survival (DFS) compared with tamoxifen in postmenopausal women with endocrine-responsive early breast cancer. Our aim was to establish...... whether the benefit of letrozole versus tamoxifen differs according to the ERBB2 status of tumours. Methods The BIG 1-98 trial consists of four treatment groups that compare 5 years of monotherapy with letrozole or tamoxifen, and sequential administration of one drug for 2 years followed by the other drug...... for 3 years. Our study includes data from the 4922 patients randomly assigned to the two monotherapy treatment groups (letrozole or tamoxifen for 5 years; 51 months median follow-up [range

Effects of alpha fetoprotein on escape of Bel 7402 cells from attack of lymphocytes

International Nuclear Information System (INIS)

Li, Mengsen; Liu, Xinhua; Zhou, Sheng; Li, Pingfeng; Li, Gang

2005-01-01

Involvement of AFP against apoptosis of tumor cell has been implicated in its evasion of immune surveillance. However, the molecular events of immune escape mechanisms are still unknown. The major observations reported here relate to a possible mechanism by which heptoloma Bel 7402 cells escape immune surveillance in vitro. Western blotting and a well-characterized cofocal scanning image were performed to analyze the expression of Fas/FasL and caspase-3 in co-cultured Bel 7402 and Jurkat cells. After co-culture with Jurkat cells, up-regulated Fas and reduced FasL expression could be observed. Treatment with AFP could remarkably inhibit the elevated Fas and, whereas, induce the FasL expression in co-cultured Bel 7402 cells. Cells co-culture could induce the expression of caspase-3 in both cells line. The elevated caspase-3 in Bel 7402 cells was abolished following the treatment of AFP. The expression of caspase-3 was elevated in co-cultured Jurkat cells treated with AFP. No detectable change on the expression of survivin was examined in both cells line. Monoclonal antibody against AFP treatment alone did not obviously influence the growth of cells, as well as the expression of Fas/FasL and caspase-3. However, the effect of AFP could be blocked by antibody. our results provide evidence that AFP could promote the escape of liver cancer cells from immune surveillance through blocking the caspase signal pathway of tumor cells and triggering the Fas/FasL interaction between tumor cells and lymphocytes

RD and D Programme 98. Treatment and final disposal of nuclear waste. Programme for research, development and demonstration of encapsulation and geological disposal

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

RD and D-Programme 98 is intended to provide an overview of SKBs activities and plans. The detailed research programme is presented in a separate background report. In parallel with RDD-Programme 98, SKB is publishing a number of reports that provide a more thorough background and a more detailed account, particularly on those issues that the Government mentioned in its decision regarding RD and D-Programme 95. The programme is divided into two parts: Background and Execution. The background part begins with a chapter on the basic premises. It deals with general principles, laws and the properties of the waste. The facilities that exist today for dealing with the nuclear waste are also described in the introductory chapter. The two following chapters have to do with the choice between different methods for disposing of nuclear waste and with the KBS-3 method, which SKB has chosen as its main alternative. These two chapters provide a broader account of both the KBS-3 method and different alternative methods than previous RD and D-programmes. The background part concludes with a chapter about the long-term safety of the deep repository. The second part, Execution, begins with an overview of SKBs strategy and the main features of the programme, both for the next few years and further in the future. The plans for siting, technology and safety assessment are then presented in greater detail. This is followed by an overview of our plans for supportive research and development, including continued R and D on other methods than the KBS-3 method. The programme concludes with a chapter on decommissioning of nuclear facilities. An important part of the ongoing and planned work is consultation on environmental impact assessments. A first draft of the contents of future environmental impact statements is therefore provided. By attaching it to RD and D-Programme 98, SKB wishes to give all reviewing bodies an opportunity to offer their viewpoints at an early stage on what future

RD and D Programme 98. Treatment and final disposal of nuclear waste. Programme for research, development and demonstration of encapsulation and geological disposal

International Nuclear Information System (INIS)

1998-09-01

RD and D-Programme 98 is intended to provide an overview of SKBs activities and plans. The detailed research programme is presented in a separate background report. In parallel with RDD-Programme 98, SKB is publishing a number of reports that provide a more thorough background and a more detailed account, particularly on those issues that the Government mentioned in its decision regarding RD and D-Programme 95. The programme is divided into two parts: Background and Execution. The background part begins with a chapter on the basic premises. It deals with general principles, laws and the properties of the waste. The facilities that exist today for dealing with the nuclear waste are also described in the introductory chapter. The two following chapters have to do with the choice between different methods for disposing of nuclear waste and with the KBS-3 method, which SKB has chosen as its main alternative. These two chapters provide a broader account of both the KBS-3 method and different alternative methods than previous RD and D-programmes. The background part concludes with a chapter about the long-term safety of the deep repository. The second part, Execution, begins with an overview of SKBs strategy and the main features of the programme, both for the next few years and further in the future. The plans for siting, technology and safety assessment are then presented in greater detail. This is followed by an overview of our plans for supportive research and development, including continued R and D on other methods than the KBS-3 method. The programme concludes with a chapter on decommissioning of nuclear facilities. An important part of the ongoing and planned work is consultation on environmental impact assessments. A first draft of the contents of future environmental impact statements is therefore provided. By attaching it to RD and D-Programme 98, SKB wishes to give all reviewing bodies an opportunity to offer their viewpoints at an early stage on what future

RES hyperphagocytosis by rats with streptozotocin-induced diabetes mellitus.

Science.gov (United States)

Cornell, R P

1981-03-01

In contrast to previous studies of neutrophils from diabetic animals and humans in vitro and of macrophages from diabetic humans in vivo, which reported phagocytic depression, reticuloendothelial system (RES) hyperphagocytosis of colloidal carbon was observed in rats at 14 and 28 days after diabetes induction with streptozotocin (STZ). Carbon clearance half times were significantly enhanced to 6.3 +/- 0.79 and 8.1 +/- 1.04 min at 14 and 28 days post-STZ, respectively, compared with the nondiabetic value (12.7 +/- 0.98 min). The severity of uncontrolled STZ-induced diabetes in rats was confirmed by significant hypoinsulinemia, hyperglucagonemia, hyperglycemia, and hyperlipidemia. Although body weights of STZ-diabetic animals declined progressively, liver weights as a percent of body weight increased above the control value at 14 and 28 days post-STZ. In fact, expression of carbon phagocytosis as the corrected phagocytic index, which accounts for changes in liver and spleen weights relative to body weight, eliminated the significant difference between STZ-diabetic and nondiabetic animals. Antibiotic treatment of diabetic rats failed to alter the hyperphagocytosis, implying that a chronic bacterial infection was not the cause of phagocytic stimulation. Daily insulin replacements, but not a single large insulin dose to 14-day post-STZ rats, reversed the enhanced phagocytosis of colloidal carbon.

Influences of MCrAlY coatings on oxidation resistance of single crystal superalloy DD98M and their inter-diffusion behaviors

Energy Technology Data Exchange (ETDEWEB)

Shi, Long [School of Materials and Metallurgy, Northeastern University, Shenyang 110819 (China); Laboratory for Corrosion and Protection, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China); Xin, Li, E-mail: xli@imr.ac.cn [Laboratory for Corrosion and Protection, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China); Wang, Xinyue; Wang, Xiaolan; Wei, Hua; Zhu, Shenglong; Wang, Fuhui [Laboratory for Corrosion and Protection, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China)

2015-11-15

Oxidation and interdiffusion behaviors of Ni-based single crystal superalloy DD98M with nominal compositions Ni–5.0Co–6.0Cr–6.3Al–6.0W–2.0Mo–6.0Ta–1.0Ti (in wt.%) and two types of MCrAlY coatings at 1000 °C and 1050 °C were investigated. Complex oxides formed on the surface of DD98M alloy when oxidized at 1000 °C and 1050 °C, which stratified, cracked and spalled. The faceted-like AlN and the particle-like and strip-like TiN formed in the alloy. The application of the NiCrAlY and NiCoCrAlYHfSi coatings greatly improved the oxidation resistance of DD98M alloy. After 500 h oxidation, α-Al{sub 2}O{sub 3} was still the dominate phase in the oxide scales formed on the coated specimens. The adhesion of the oxide scale on the NiCoCrAlYHfSi coating was much better than that on the NiCrAlY coating. Interdiffusion occurred between the coatings and the substrate, which led to the formation of the IDZ and SRZ. The IDZ of the NiCrAlY coated specimen was composed of γ phase and Al- and Ta-rich γ′ phase. The γ′ phase in the IDZ accommodated most of the inward diffusing aluminum, so the SRZ formation was suppressed when oxidized at 1050 °C. However the formation of SRZ with μ-TCP still occurred when oxidized at 1000 °C probably due to the low solubility and slow diffusion rate of the alloying elements at lower temperature. The IDZ of the NiCoCrAlYHfSi coated specimen was a single γ phase. A large amount of μ-TCP precipitated in the SRZ of the NiCoCrAlYHfSi coated specimen when oxidized at 1000 °C and 1050 °C. It can be concluded coating composition has a significant effect on the development of the IDZ and SRZ. Thermal exposure temperature also has influences on the formation of the SRZ. The mechanism of SRZ formation and TCP precipitation are discussed. - Graphical abstract: The TEM micrograph of the IDZ and SRZ of the NiCoCrAlYHfSi-coated specimen oxidized at 1050 °C for 100 h and the respective diffraction patterns of the needle-like and the

Haljalas valmistatud pehme mööbel vallutab Skandinaavia kodusid / Signe Kalberg

Index Scriptorium Estoniae

Kalberg, Signe, 1959-

2009-01-01

Edukast pehme mööbli firmast Bellus Furniture. Ajakohased tootmisliinid võimaldavad valmistada 160 mööblimudelit. 98 % firma toodangust läheb ekspordiks Rootsi, Soome, Norrasse, Taani ja Beneluxi maadesse. Omanikud: Rolf ja Rikard Mikael Relander. Disainerid: Heikki Toripainen ja Kaie Veissbach

Kritisk självreflektion i komplexa frågor: Att hjälpa studenterna att ta makten över sitt tänkande

Directory of Open Access Journals (Sweden)

Maria Wolrath Söderberg

2017-12-01

Full Text Available Den här artikeln handlar om studenters kritiska självreflektion. Utgångspunkten är att de former av kritiskt tänkande som vi traditionellt odlar inom högskolan är otillräckliga när det gäller vår tids kritiska frågor, som exempelvis klimatfrågan. När det rör sig om komplexa och värdeladdade frågor där många perspektiv kan vara giltiga har vi att förhålla oss till olika mänskliga mekanismer som på olika vis hindrar oss från att tänka och agera klokt, exempelvis polarisering, bekräftelsebias, glapp mellan tanke och handling och olika former av legitimeringsstrategier för att låta blir att ta ansvar. Här diskuteras sådana hinder och hur vi kan förhålla oss till dem i högre utbildning.

Effect of Hyperoxygenation on Tissue pO2 and Its Effect on Radiotherapeutic Efficacy of Orthotopic F98 Gliomas

International Nuclear Information System (INIS)

Khan, Nadeem; Mupparaju, Sriram M.S.; Hekmatyar, Shahryar K.; Hou Huagang; Lariviere, Jean P.; Demidenko, Eugene; Gladstone, David J.; Kauppinen, Risto A.; Swartz, Harold M.

2010-01-01

Purpose: Lack of methods for repeated assessment of tumor pO 2 limits the ability to test and optimize hypoxia-modifying procedures being developed for clinical applications. We report repeated measurements of orthotopic F98 tumor pO 2 and relate this to the effect of carbogen inhalation on tumor growth when combined with hypofractionated radiotherapy. Methods and Materials: Electron paramagnetic resonance (EPR) oximetry was used for repeated measurements of tumor and contralateral brain pO 2 in rats during 30% O 2 and carbogen inhalation for 5 consecutive days. The T 1 -enhanced volumes and diffusion coefficients of the tumors were assessed by magnetic resonance imaging (MRI). The tumors were irradiated with 9.3 Gy x 4 fractions in rats breathing 30% O 2 or carbogen to determine the effect on tumor growth. Results: The pretreatment F98 tumor pO 2 varied between 8 and 16 mmHg, while the contralateral brain had 41 to 45 mmHg pO 2 during repeated measurements. Carbogen breathing led to a significant increase in tumor and contralateral brain pO 2 ; however, this effect declined over days. Irradiation of the tumors in rats breathing carbogen resulted in a significant decrease in tumor growth and an increase in the diffusion coefficient measured by MRI. Conclusions: The results provide quantitative measurements of the effect of carbogen inhalation on intracerebral tumor pO 2 and its effect on therapeutic outcome. Such direct repeated pO 2 measurements by EPR oximetry can provide temporal information that could be used to improve therapeutic outcome by scheduling doses at times of improved tumor oxygenation. EPR oximetry is currently being tested for clinical applications.

Sexuelle Belästigung aus strafrechtlicher Sicht Sexual Harassment from the Perspective of Criminal Law

Directory of Open Access Journals (Sweden)

Maria Eder-Rieder

2004-07-01

Full Text Available Der Kern der Arbeit ist die juristische Aufarbeitung der Grenzen und Reichweite der in der Schweiz seit 1. Oktober 1992 in Kraft befindlichen Regelungen zur sexuellen Belästigung durch Vornahme einer sexuellen Handlung vor jemanden (Art. 198 Abs. 1 StGB, der tätlichen sexuellen Belästigung und der verbalen Belästigung (Art. 198 Abs. 2 StGB. Diese Tatbestände werden anhand von Beispielen erläutert, mit weiteren Varianten der sexuellen Belästigung verglichen und zu anderen Tatbeständen abgegrenzt. Ebenso wird auf das Verhältnis zum Zivilrecht und die Problematik des Strafprozesses eingegangen. Abschließend wird der kriminalpolitischen Frage über den Sinn der strafrechtlichen Sanktionierung nachgegangen.The core of this work is the judicial reappraisal of the boundaries and range of Swiss regulations—effective since October 1, 1992—on sexual harassment through carrying out a sexual action in the presence of someone (Art. 198 Paragraph 1 of the penal code or violent sexual harassment and verbal harassment (Art. 198 Paragraph 2 of the penal code. These elements of offences are illustrated on the basis of examples, are compared to further variations of sexual harassment and are distinguished from other offences. The relationship between civil law and the difficulties of criminal procedures are also dealt with. At the end of the book, the criminal-political question of the meaning of penal sanctions is examined.

Nucleation on a stepped surface with an Ehrlich–Schwöbel barrier

International Nuclear Information System (INIS)

Chromcova, Z; Chvoj, Z; Tringides, M C

2013-01-01

During deposition on a stepped surface the growth mode depends on the conditions such as temperature T, deposition rate F and width of the terraces w. In this work we studied the influence of all the above mentioned characteristics using the kinetic Monte Carlo (kMC) technique. We concentrated on the conditions on the terrace at the moment of the first nucleation. The critical density of monomers for nucleation η m decreases with the width of the terrace and the nucleation starts at surprisingly low densities of monomers. We tested several definitions of the critical width for nucleation w c used in various articles in the past and we compared our results with results of the analytical steady-state mean-field model (Ranguelov and Altman 2007 Phys. Rev. B 75 245419). To check how the simplified assumption about the steady-state regime during deposition influences the resulting dependence of w c ≃ (D/F) κ , we set and also solved a time-dependent analytical model. This analytical model as well as kMC predict that w c ≃ (D/F) 1/5 . kMC simulation also shows that the Ehrlich–Schwöbel barrier has only limited influence on the nucleation on the stepped surface at conditions close to the nucleation regime. For all widths of terraces there is a critical value of the Ehrlich–Schwöbel barrier, and only below this critical value does the Ehrlich–Schwöbel barrier affect the final value of the density of nuclei. The results of the kMC are summarized in a semi-empirical analytical formula which describes the dependence of the step-flow growth and nucleation on the terrace width w, diffusion coefficient D and deposition rate F. In our simulations we tested two models of the stepped surface with different thicknesses of the step, both with an Ehrlich–Schwöbel barrier on the edge of the terrace. (paper)

Hållbarhetsredovisning : Identifiering och prioritering av hållbarhetsfrågor i en verksamhet som Sweco Environment

OpenAIRE

Söderström, Anna-Karin

2017-01-01

I en hållbarhetsredovisning redovisar en organisation information om sin påverkan inom ekonomisk, miljömässig och social hållbar utveckling. Några av de inledande stegen i en redovisningsprocess är att identifiera organisationens hållbarhetsfrågor, och att bestämma frågornas prioriteringsordning för att på så sätt kunna bestämma ett väsentligt innehåll till redovisningen. De här stegen av redovisningsprocessen har varit i fokus under arbetet. En identifiering och prioritering av konsultbolage...

Proceedings of the 2nd NUCEF international symposium NUCEF`98. Safety research and development of base technology on nuclear fuel cycle

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

This volume contains 68 papers presented at the 2nd NUCEF International Symposium NUCEF`98 held on 16-17 November 1998, in Hitachinaka, Japan, following the 1st symposium NUCEF`95 (Proceeding: JAERI-Conf 96-003). The theme of this symposium was `Safety Research and Development of Base Technology on Nuclear Fuel Cycle`. The papers were presented in oral and poster sessions on following research fields: (1) Criticality Safety, (2) Reprocessing and Partitioning, (3) Radioactive Waste Management. The 68 papers are indexed individually. (J.P.N.)

Proceedings of the 2nd NUCEF international symposium NUCEF'98. Safety research and development of base technology on nuclear fuel cycle

International Nuclear Information System (INIS)

1999-03-01

This volume contains 68 papers presented at the 2nd NUCEF International Symposium NUCEF'98 held on 16-17 November 1998, in Hitachinaka, Japan, following the 1st symposium NUCEF'95 (Proceeding: JAERI-Conf 96-003). The theme of this symposium was 'Safety Research and Development of Base Technology on Nuclear Fuel Cycle'. The papers were presented in oral and poster sessions on following research fields: (1) Criticality Safety, (2) Reprocessing and Partitioning, (3) Radioactive Waste Management. The 68 papers are indexed individually. (J.P.N.)

Comments on 'SKB RD and D-Programme 98'. Focused on canister integrity and corrosion

International Nuclear Information System (INIS)

Bowyer, W.H.; Hermansson, H.P.

1999-04-01

According to the Act on Nuclear Activities the nuclear utilities are requested to submit a comprehensive programme for research and development every third year, aiming at the safe storage of radioactive waste produced by the nuclear power plants. The latest was published by SKB in September 1998 and is called the 'RDandD Programme 98'. The work presented in the present report was commissioned by SKI and is a result of reading the 'RDandD Programme 98' and related reports with focus on canister production, integrity and corrosion. We find that those parts of the programme often are difficult to follow owing to the lack of detail in the Programme and in one of the supporting reports. In our opinion this will make the work difficult to monitor by SKI and SKB. We also feel that the interpretation of information already available often is overoptimistic. As a consequence the difficulties ahead are understated and the programme is allowed to converge too quickly. We agree that the materials choices for both the inner and outer canisters are appropriate providing they both can be produced commercially and in a satisfactory metallurgical condition, that they can be quality assured and that no further unforeseen difficulties arise. We also agree that alternative technologies merit consideration for production of the outer canister and that alternative joining processes should be studied. We are actually concerned that greater prominence is not given to the alternatives in the programme. We believe that it should be possible to develop a satisfactory canister for disposal of high level nuclear waste according to the general method proposed by SKB and with the proposed capacity within the time-scale of the overall programme. We do not believe, however, that all the difficulties have been recognised. As a consequence of this the results to date are interpreted optimistically. We believe that progress should be subjected to more professional review within SKB and that a higher

Phase II Hydrologic Data for the Groundwater Flow and Contaminant Transport Model of Corrective Action Unit 98: Frenchman Flat, Nye County, Nevada, Rev. No.: 0

Energy Technology Data Exchange (ETDEWEB)

John McCord

2004-12-01

This report documents pertinent hydrologic data and data analyses as part of the Phase II Corrective Action Investigation (CAI) for Frenchman Flat (FF) Corrective Action Unit (CAU): CAU 98. The purpose of this data compilation and related analyses is to provide the primary reference to support the development of the Phase II FF CAU groundwater flow model.

Integrated HLW Conceptual Process Flowsheet(s) for the Crystalline Silicotitanate Process SRDF-98-04

International Nuclear Information System (INIS)

Jacobs, R.A.

1998-01-01

The Strategic Research and Development Fund (SRDF) provided funds to develop integrated conceptual flowsheets and material balances for a CST process as a potential replacement for, or second generation to, the ITP process. This task directly supports another SRDF task: Glass Form for HLW Sludge with CST, SRDF-98-01, by M. K. Andrews which seeks to further develop sludge/CST glasses that could be used if the ITP process were replaced by CST ion exchange. The objective of the proposal was to provide flowsheet support for development and evaluation of a High Level Waste Division process to replace ITP. The flowsheets would provide a conceptual integrated material balance showing the impact on the HLW division. The evaluation would incorporate information to be developed by Andrews and Harbour on CST/DWPF glass formulations and provide the bases for evaluating the economic impact of the proposed replacement process. Coincident with this study, the Salt Disposition Team began its evaluation of alternatives for disposition of the HLW salts in the SRS waste tanks. During that time, the CST IX process was selected as one of four alternatives (of eighteen Phase II alternatives) for further evaluation during Phase III

Characteristics of the Gamow-Teller Force in the β- Decay of 40Zr98

International Nuclear Information System (INIS)

Raden Oktova

2002-01-01

The characteristics of the β - decay force for the Gamow-Teller transition in the p-h and the p-p channels in the heavy neutron-rich nucleus 40 Zr 98 have been studied. The ground state single-particle levels in the parent nucleus were calculated self-consistently using the Fayans energy-density functional, and from them the quasi-particle basis was obtained using the BCS model. The residual charge-changing force responsible for the β - transition was taken as having a zero-range (a delta function); in the p-h channel the spin-isospin exchange → σ 1 . → σ 2 → τ 1 . → τ 2 term in the Migdal-Larkin force was used, and that in the p-p channel was a constant. The method employed was the proton-neutron QRPA (pnQRPA). The results show that the proton-neutron pairing p-p force in the Gamow-Teller decay is negligible for the nucleus considered. The value of the p-h force obtained is g ' = 0.735, slightly larger than the standard value of g ' = 0.7 commonly used for stable nuclei. (author)

Hurlburt Field, Valparaiso, Florida. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

Science.gov (United States)

1972-05-25

I__o0_,_o 1 , , -, IV~I~ I , t ~ , I V ! , , __ 00_ , _- _ z I SooI S1000 I I S700 600 I.,, _ . o I. Io o 2: 300I 2: 200 _ _1.........__ _ 0___ 9...2 i0195# 95# 95@ 95*8 96 s 10 9-6"i 0 S700 781 13..? ,90.1 9Z.7 94:, 19091b 60 964 694 96,7 96v9 96 ,9791 97.11 97, 1 97,! 6 120.o10,00 90.8 7.5 94.b...90., 983,S 94# 989, 98,7 98,7 8,7 98,7 S700 474 ?), 96@4 97#o 97.6 979’ 9Uf? 98,b 980$ 91.,8 980a 98.11 90,9 91109 98.9 98,9 - 600 7,4 935 9qI 97.1

p-STAT3 in luminal breast cancer: Integrated RNA-protein pooled analysis and results from the BIG 2-98 phase III trial.

Science.gov (United States)

Sonnenblick, Amir; Salgado, Roberto; Brohée, Sylvain; Zahavi, Tamar; Peretz, Tamar; Van den Eynden, Gert; Rouas, Ghizlane; Salmon, Asher; Francis, Prudence A; Di Leo, Angelo; Crown, John P A; Viale, Giuseppe; Daly, Laura; Javdan, Bahar; Fujisawa, Sho; De Azambuja, Evandro; Lieveke, Ameye; Piccart, Martine J; Bromberg, Jacqueline F; Sotiriou, Christos

2018-02-01

In the present study, in order to investigate the role of signal transducer and activator of transcription 3 (STAT3) in estrogen receptor (ER)-positive breast cancer prognosis, we evaluated the phosphorylated STAT3 (p-STAT3) status and investigated its effect on the outcome in a pooled analysis and in a large prospective adjuvant trial. By using the TCGA repository, we developed gene signatures that reflected the level of p-STAT3. Using pooled analysis of the expression data from luminal breast cancer patients, we assessed the effects of the p-STAT3 expression signature on prognosis. We further validated the p-STAT3 prognostic effect using immunohistochemistry (IHC) and immunofluorescence staining of p-STAT3 tissue microarrays from a large randomised prospective trial. Our analysis demonstrated that p-STAT3 expression was elevated in luminal A-type breast cancer (Kruskal-Wallis test, PBIG 2-98 randomised trial. With a median follow-up of 10.1 years, p-STAT3 was associated with a reduced risk of recurrence in ER-positive/HER2-negative breast cancer (Cox univariate HR, 0.66; 95% CI, 0.44-0.98; P=0.04). On the whole, our data indicate that p-STAT3 is associated with an improved outcome in ER-positive breast cancer.

Utilization of a novel electrochemical {sup 90}Sr/{sup 90}Y generator for the preparation of {sup 90}Y-labeled RGD peptide dimer in clinically relevant dose

Energy Technology Data Exchange (ETDEWEB)

Chakraborty, Sudipta; Chakravarty, Rubel; Pillai, Maroor Raghavan Ambikalmajan; Dash, Ashutosh [Bhabha Atomic Research Centre, Mumbai (India). Radiopharmaceuticals Div.; Sarma, Haladhar Dev [Bhabha Atomic Research Centre, Mumbai (India). Radiation Biology and Health Sciences Div.

2014-09-01

The work reported in this paper provides a systematic study towards the development of an optimized strategy for preparation of a clinically relevant dose of {sup 90}Y-labeled dimeric RGD peptide derivative, DOTA-E[c(RGDfK)]{sub 2} [DOTA-(RGD){sub 2}] for in vivo targeted therapy utilizing {sup 90}Y obtained from a novel electrochemical {sup 90}Sr/{sup 90}Y generator. The performance of the generator was evaluated to ensure its suitability for providing {sup 90}Y in adequate quantity and purity required for formulation of clinically relevant dose for PRRT. {sup 90}Y-DOTA-(RGD){sub 2} was synthesized in high yield (86.2 ± 2.5%) and radiochemical purity (98.4 ± 0.5%) using clinically relevant dose (∝ 3.8 GBq) of {sup 90}Y. In vitro stability studies revealed that the radiolabeled conjugate retained its radiochemical purity in normal saline and human serum. Preliminary biodistribution studies carried out in C57/BL6 mice bearing melanoma tumors showed that the preparation exhibited significant tumor uptake (5.30 ± 0.78% of injected activity at 30 min post-injection) with good tumor to background ratio. The optimized radiolabeling protocol seems to be an attractive strategy which is largely viewed as a springboard to realize scope of developing {sup 90}Y labeled cyclic RGD peptides for targeted therapy of tumors over-expressing integrin-α{sub ν}β{sub 3} receptors. (orig.)

ETRAN '98: Society for Electronics,Telecommunications, Computers, Automation and Nuclear Engineering. Section for Nuclear Techniques and Technology. Proceedings of the XLII Conference. Vol IV

International Nuclear Information System (INIS)

Matausek, M.

1998-01-01

This volume 4, includes 29 papers presented at the Sessions on Nuclear science and technology of the ETRAN '98 conference. The topics covered were related to solving the problems of the spent fuels storage at the RA reactor, fuel management calculations, computation of neutron and photon spectra at the RA and RB reactors, applications of radiation sources in medicine and industry, radiation protection issues

A Revised Velocity for the Globular Cluster GC-98 in the Ultra Diffuse Galaxy NGC 1052-DF2

Science.gov (United States)

van Dokkum, Pieter; Cohen, Yotam; Danieli, Shany; Romanowsky, Aaron; Abraham, Roberto; Brodie, Jean; Conroy, Charlie; Kruijssen, J. M. Diederik; Lokhorst, Deborah; Merritt, Allison; Mowla, Lamiya; Zhang, Jielai

2018-06-01

We recently published velocity measurements of luminous globular clusters in the galaxy NGC1052-DF2, concluding that it lies far off the canonical stellar mass - halo mass relation. Here we present a revised velocity for one of the globular clusters, GC-98, and a revised velocity dispersion measurement for the galaxy. We find that the intrinsic dispersion $\\sigma=5.6^{+5.2}_{-3.8}$ km/s using Approximate Bayesian Computation, or $\\sigma=7.8^{+5.2}_{-2.2}$ km/s using the likelihood. The expected dispersion from the stars alone is ~7 km/s. Responding to a request from the Editors of ApJ Letters and RNAAS, we also briefly comment on the recent analysis of our measurements by Martin et al. (2018).

Quantitative Interpretation of X-ray Absorption Near Structure Continuation Progress Report for 1st year 9/15/98-9/14/99

International Nuclear Information System (INIS)

Rehr, John J.; Bare, Simon; Stocht, Joachim

1999-01-01

OAK-B135 Quantitative Interpretation of X-ray Absorption Near Structure Continuation Progress Report for 1st year 9/15/98-9/14/99. This paper proposes to develop two industrial research collaborations to further develop the FEFF8 x-ray spectroscopy code to achieve a quantitative interpretation of x-ray absorption near edge structure (XANES) in materials of interest in energy research: (a) Quantitative interpretation of XANES for heterogeneous catalysts and disordered materials; and (b) quantitative interpretation of white-lines in XANES. The paper also outlines significant results achieved during the first Grant year

Photojournalism in the Belém Press: 1900–1950

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Netília Silva dos Anjos Seixas

2015-12-01

Full Text Available This study looks at the course of photojournalism in the first half of the 20th century in the Belém press, in the State of Pará. This is exploratory research based on the iconographic and iconological analysis of images as understood by Panofsky and Kossoy. Bibliographical and documentary research together with an empirical analysis of data was conducted on three important newspapers in Pará: A Província do Pará, Folha do Norte and Estado do Pará, all available in the archives of the Arthur Vianna Public Library in Belém. Analyzing the data made it possible to provide a picture of the course of photojournalism in Pará for the major newspapers in circulation during the established time period, showing that even at the beginning of the century periodicals already recognized the power of images; something evident in publication. The data also showed that problems in the city, wars, politics, police and sports were the main issues for photojournalism in Pará throughout the decades studied in this paper.

Avaliação de risco crônico da ingestão de resíduos de pesticidas na dieta brasileira Chronic dietary risk assessment for pesticide residues in Brazilian food

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Eloisa Dutra Caldas

2000-10-01

Full Text Available OBJETIVO: Avaliar o risco crônico da ingestão de pesticidas pela dieta, em compostos registrados no Brasil para uso agrícola até 1999. MÉTODOS: Foi calculada a Ingestão Diária Máxima Teórica (IDMT para cada pesticida, utilizando limites máximos de resíduos estabelecidos pela legislação brasileira e dados de consumo alimentar. A caracterização do risco foi feita comparando-se a IDMT com as doses diárias aceitáveis (IDA de vários países e do Codex Alimentarius. RESULTADOS: A IDTM ultrapassou a IDA (%IDA>100 em pelo menos uma região metropolitana brasileira para 23 pesticidas. Dezesseis compostos com maior %IDA são inseticidas organofosforados, sendo o paration metílico o composto cuja ingestão mais excedeu o parâmetro toxicológico (%IDA N=9.300. O arroz, o feijão, as frutas cítricas e o tomate foram os alimentos que mais contribuíram para a ingestão. Dos compostos que apresentaram maior risco, apenas 6 foram registrados de acordo com o Decreto 98.816/90, que dispõe sobre o uso de pesticidas no País. CONCLUSÕES: Os compostos identificados como sendo de potencial risco de exposição crônica para a população brasileira, e os alimentos que mais contribuíram para a sua ingestão, devem ser priorizados pelos órgãos de saúde em programas de monitoramento de resíduos de pesticidas. Adicionalmente, dados sobre resíduos em alimentos prontos para o consumo, fatores de processamento e dados sobre consumo alimentar devem ser gerados para possibilitar o refinamento do estudo.OBJECTIVE: To conduct a chronic dietary risk assessment of the pesticides registered in Brazil up until 1999. METHODS: The Theoretical Maximum Daily Intake (TMDI for each pesticide was calculated using the Brazilian maximum residue limits and food consumption data from IBGE, the Brazilian Statistical Institute. The risk characterization was done comparing the TMDI with the acceptable daily intakes (ADI from other countries and from the Codex

Optimization of Subcritical Water Extraction of Resveratrol from Grape Seeds by Response Surface Methodology

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Yajie Tian

2017-03-01

Full Text Available The subcritical water extraction (SWE is a high-efficiency and environment-friendly extraction method. The extraction of resveratrol (RES of grape seeds obtained from the wine production process was proposed using subcritical water extraction (SWE. The effects of different extraction process parameters on RES yield were investigated by single factors. Extraction optimization was conducted using response surface methodology (RSM. Extraction temperature was proven to be the most significant factor influencing RES yield. The optimal conditions was as follows: extraction pressure of 1.02 MPa, temperature of 152.32 °C, time of 24.89 min, and a solid/solvent ratio of 1:15 g/mL. Under these optimal conditions, the predicted extraction RES yield was 6.90 μg/g and the recoveries was up to 91.98%. Compared to other previous studies, this method required less pollution and less treatment time to extract RES from grape seeds. From these results, added economic value to this agroindustrial residue is proposed using environmentally friendly extraction techniques.

McConnell AFB, Witchita, Kansas. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

Science.gov (United States)

1981-12-14

96. 96. 97. 97.3 979; 97.8 97.9 97.9 97.9 97.9 97.9 97.9 97.9~~v 78q9o 5q90 7 90 8u 98.380 6� 98*7 98, �,7 98,7 S700 95:1 9b:’ 08’ 0 * 98o77 6...69o9 7301 70.2 70.2 70.3 7003 70.3 70.3 70o3 70.4 70o4 73.4 7o.4 : 8000 50 71, 71T6 71o 72 701 T71 -72 F2 7 o3 72.3 -.1 72,3 72 o 3 72.3 M7 2 ,3. S700 ...97.5 97.5 97o5 97o5 97,5 Roo 80. 95. 96. 97. 97s 97. 97. 98.1 98.1 98.1 98.1 98.1 98.1 98.1 98.1 Q81 S700 8 8 98 8 98. 98. 98. . 98. 9811117 17 17 .8

In situ X-ray and neutron diffraction of the Ruddlesden-Popper compounds (RE2-xSrx)0.98(Fe0.8Co0.2)1-yMgyO4-δ (RE=La, Pr): Structure and CO2 stability

DEFF Research Database (Denmark)

Chatzichristodoulou, Christodoulos; Hauback, B.C.; Hendriksen, Peter Vang

2013-01-01

The crystal structure of the Ruddlesden-Popper compounds (La 1.0Sr1.0)0.98Fe0.8Co 0.2O4-δ and (La1.2Sr0.8) 0.98(Fe0.8Co0.2)0.8Mg 0.2O4-δ was investigated at 1000 °C in N 2 (aO2=1×10-4) by in-situ powder neutron diffraction. In-situ powder X-ray diffraction (PXD) was also employed to investigate....... The equivalent pseudo-cubic thermal and chemical expansion coefficients are in agreement with values determined by dilatometry. The chemical stability in CO2 containing environments of various Ruddlesden-Popper compounds with chemical formula (RE2-xSr x)0.98(Fe0.8Co0.2) 1-yMgyO4-δ (RE=La, Pr), as well...

Q fever in the Greek Island of Crete: epidemiologic, clinical, and therapeutic data from 98 cases.

Science.gov (United States)

Tselentis, Y; Gikas, A; Kofteridis, D; Kyriakakis, E; Lydataki, N; Bouros, D; Tsaparas, N

1995-05-01

A retrospective study was undertaken in Crete, Greece, to investigate the epidemiologic, clinical, and therapeutic aspects of Q fever. Over a period of 5 years (1989-1993), 1,298 patients were examined and 98 cases were identified. Individuals who were aged 20-29 years and 30-39 years appeared to have an increased risk of infection. Contact with animals was found to be a major risk factor for acquisition of Q fever. The predominant clinical manifestations of the infection were fever (91.7% of patients) and respiratory disease (88.5%), whereas hepatitis was the dominant feature in only a minority (7.1%) of patients. Chest radiographs frequently revealed pulmonary interstitial changes (36.4% of patients) and alveolar changes (34.4%). Abnormal echocardiographic findings were also observed. There was no difference in the duration of fever whether the patient received therapy with tetracycline or erythromycin, a finding that may be explained by the delay in initiating tetracycline therapy.

Directly transport of suspended matter from the Yangtze River to the Okinawa trough post-major flood '98: evidence from stable isotopes and C/N ratios

International Nuclear Information System (INIS)

Cai Deling; Shi Xuefa; Song Xiaohong

2007-01-01

Water column concentrations of total suspended matter (TSM), particulate organic carbon (POC), particulate nitrogen (PN) and their stable isotopic compositions (δ 13 C and δ 15 N) are measured at two to five different depths in the Yellow Sea and East China Seas and Yangtze Estuary to clarify the effect of '98 Yangtze great flood on the transport of suspended matter in the Yellow Sea and East China Sea. Suspended matters are collected to analyze the distributions of TSM, POC, PN and salinity throughout the Yellow Sea and East China Sea in the autumn of 1998. There are marked positive correlations (r=0.89-0.98) among TSM, POC and PN, but negative relationships (r=-0.29 - -0.59) between TSM and salinity. These results conclude that the POC and PN were controlled primarily by the concentrations of TSM. The C/N ratios of particulate organic matter have a negative linear correlation with PN% (r=-0.44 - -0.71), but no correlation with POC%, which suggests C/N ratios are mainly controlled by PN%. There are distinct positive correlations between δ 15 N and POC% or PN% in surface water (r=0.36 and 0.24, p<0.01, respectively), however, the correlation do not exist in more deeper depths. In indicates that δ 15 N PN could be changed by a lot of factors, such as nutrient availability, nitrification, denitrification, different material sources and so on, except decomposition of organic matter. The distributions of C/N ratios and δ 13 C values of the particulate organic matter suggest that suspended matters from Yangtze River could be transported directly into the Okinawa Trough under the condition of '98 Yangtze major flood, which break through the foregone knowledge obtained under the normal hydrological condition. (authors)

Phase II Contaminant Transport Parameters for the Groundwater Flow and Contaminant Transport Model of Corrective Action Unit 98: Frenchman Flat, Nye County, Nevada, Rev. No.: 0

Energy Technology Data Exchange (ETDEWEB)

DeNovio, Nicole M.; Bryant, Nathan; King, Chrissi B.; Bhark, Eric; Drellack, Sigmund L.; Pickens, John F.; Farnham, Irene; Brooks, Keely M.; Reimus, Paul; Aly, Alaa

2005-04-01

This report documents pertinent transport data and data analyses as part of the Phase II Corrective Action Investigation (CAI) for Frenchman Flat (FF) Corrective Action Unit (CAU) 98. The purpose of this data compilation and related analyses is to provide the primary reference to support parameterization of the Phase II FF CAU transport model.

Spectroscopic Quadrupole Moments in {96,98}Sr: Evidence for Shape Coexistence in Neutron-Rich Strontium Isotopes at N=60.

Science.gov (United States)

Clément, E; Zielińska, M; Görgen, A; Korten, W; Péru, S; Libert, J; Goutte, H; Hilaire, S; Bastin, B; Bauer, C; Blazhev, A; Bree, N; Bruyneel, B; Butler, P A; Butterworth, J; Delahaye, P; Dijon, A; Doherty, D T; Ekström, A; Fitzpatrick, C; Fransen, C; Georgiev, G; Gernhäuser, R; Hess, H; Iwanicki, J; Jenkins, D G; Larsen, A C; Ljungvall, J; Lutter, R; Marley, P; Moschner, K; Napiorkowski, P J; Pakarinen, J; Petts, A; Reiter, P; Renstrøm, T; Seidlitz, M; Siebeck, B; Siem, S; Sotty, C; Srebrny, J; Stefanescu, I; Tveten, G M; Van de Walle, J; Vermeulen, M; Voulot, D; Warr, N; Wenander, F; Wiens, A; De Witte, H; Wrzosek-Lipska, K

2016-01-15

Neutron-rich {96,98}Sr isotopes have been investigated by safe Coulomb excitation of radioactive beams at the REX-ISOLDE facility. Reduced transition probabilities and spectroscopic quadrupole moments have been extracted from the differential Coulomb excitation cross sections. These results allow, for the first time, the drawing of definite conclusions about the shape coexistence of highly deformed prolate and spherical configurations. In particular, a very small mixing between the coexisting states is observed, contrary to other mass regions where strong mixing is present. Experimental results have been compared to beyond-mean-field calculations using the Gogny D1S interaction in a five-dimensional collective Hamiltonian formalism, which reproduce the shape change at N=60.

Characteristics of the surface water basins of the Ukrainian Danube region toxicity with the use of microbial test–system Salmonella typhimurium ТА 98

Directory of Open Access Journals (Sweden)

L. I. Kovalchuk

2015-04-01

  The results of  the surface water basins of the Ukrainian Danube region  toxicity with the use of microbial test –system Salmonella typhimurium ТА 98.  The samples investigated testify about a majority of pollutants which are in the water. It has been shown that the most part of the samples under analysis had a powerful toxic effect. The percentage of the water samples with test – system toxicity equal to 90.0% was 13,3 %; with toxicity equal to 80,0 %  – 13,3 %;  with toxicity  > 50,0%  – 53,0 %; with toxicity 50,0%  – 53,0 %; на рівні 50,0%  – 53,0 %; на уровне < 20,0%  – 13,3 %. Процент нетоксичных образцов воды   составлял 6,6 %. Посколько тест-система Salmonella typhimurium ТА 98 более чувствительна к загрязнителям органического происхождения, высказана мысль, что загрязнение образцов воды связано именно с присутствием некоторых органических соединений, которые имеют большой негативный биологический потенциал. Принимая во внимание персистирующий характер загрязнения поверхностных водоемов Украинского Придунавья, признано необходимым продолжение исследований токсичности  воды этих водных объектов на бактериальной тест-системе Salmonella typhimurium ТА 98.   Ключевые слова: вода, водные объекты, токсичность,  тест-система Salmonella typhimurium TA 98, Украинское Придунавье.

Copépodes, Cladocères et Rotifères du lac Sidi M'hamed Benali (Algérie Nord-Occidentale

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Mohamed Ali Bouzidi

2010-03-01

Full Text Available En 2008, 33 espèces de Cladocères, Copépodes et Rotifères ont été observées dans le lac Sidi M'hamed Benali (contre 12 seulement en 1992.Les Copépodes dominent en mars, avril, juillet, août et septembre, avec respectivement des dominances (Do égales à : 56,6 %, 55,0 %, 55,0 %, 46,4 % et 90,0 %. Les Cladocères dominent en février (Do = 37,2 %, mai (Do = 47,4 % et décembre (Do = 48,6 %. Les Rotifères sont extrêmement abondants et présentent une large dominance en janvier (Do = 95,3 %. La population zooplanctonique est très faible en juillet et en août. Au cours de l'année le peuplement varie en fonction de la température, des conditions hydrologiques, de l'abondance de la nourriture et de la prédation par les poissons.In 2008, 33 species of Cladocers, Copepods and Rotifers have been observed in Sidi M’hamed Benali Lake (against only 12 species in 1992. The Copepods dominate in March, April, July, August and September, respectively with dominance (Do equal to 56.6 %, 55.0 %, 55.0 %, 46.4 % and 90.0 %. Cladocers dominated in February (Do = 37.2 %, May (Do = 47.4 % and December (Do = 48.6 %. The rotifers are extremely abundant and have a wide dominance in January (Do = 95.3%. The zooplankton population is very low in July and August. During the year, the population varies with temperature, water conditions, abundance of food and predation by fishes.

Factors that Influence the Use of Climate Forecasts: Evidence from the 1997/98 El Niño Event in Peru.

Science.gov (United States)

Orlove, Benjamin S.; Broad, Kenneth; Petty, Aaron M.

2004-11-01

This article analyzes the use of climate forecasts among members of the Peruvian fishing sector during the 1997/98 El Niño event. It focuses on the effect of the time of hearing a forecast on the socioeconomic responses to the forecast. Findings are based on data collected from a survey of 596 persons in five ports spanning the length of the Peruvian coast. Respondents include commercial and artisanal fishers, plant workers, managers, and firm owners.These data fill an important gap in the literature on the use of forecasts. Though modelers have discussed the effects of the timing of the dissemination and reception of forecasts, along with other factors, on acting on a forecast once it has been heard, few researchers have gathered empirical evidence on these topics.The 1997/98 El Niño event was covered extensively by the media throughout Peru, affording the opportunity to study the effect of hearing forecasts on actions taken by members of a population directly impacted by ENSO events. Findings of this study examine the relationships among 1) socioeconomic variables, including geographic factors, age, education, income level, organizational ties, and media access; 2) time of hearing the forecast; and 3) actions taken in response to the forecast. Socioeconomic variables have a strong effect on the time of hearing the forecast and the actions taken in response to the forecast; however, time of hearing does not have an independent effect on taking action. The article discusses the implications of these findings for the application of forecasts.A supplement to this article is available online (dx.doi.org/10.1175/BAMS-85-11-Orlove)

Analysis of waste hierarchy in the European waste directive 2008/98/EC.

Science.gov (United States)

Gharfalkar, Mangesh; Court, Richard; Campbell, Callum; Ali, Zulfiqur; Hillier, Graham

2015-05-01

Loss of recoverable resources in linear resource flow systems is likely to contribute to the depletion of natural resources and environmental degradation. The 'waste hierarchy' in the European Commission's latest Waste Framework Directive 2008/98/EC (WFD2008) makes recommendations on how to address this issue. The WFD2008 is analysed in this work for its adequacy in ensuring return of 'recoverable waste' as a 'resource' into the productive system. Despite the release of guidance documents by the DG Environment, DEFRA and WRAP UK on the interpretation of key provisions of the WFD2008, lack of clarity still exists around the WFD2008 'waste hierarchy'. There is also an overlap between measures such as 'prevention' and 'reduction', 'preparing for reuse' and 'reuse' and lack of clarity on why the measure of 'reuse' is included in the WFD2008 definition of 'prevention'. Finally, absence of the measures of 'recovery' and 'reuse' from the WFD2008 'waste hierarchy' reduces its effectiveness as a resource efficiency tool. Without clarity on the WFD2008 'waste hierarchy', it is challenging for decision makers to take direct action to address inefficiencies existing within their operations or supply chains. This paper proposes the development of an alternative 'hierarchy of resource use' and alternative 'definitions' that attempt to fill identified gaps in the WFD2008 and bring clarity to the key measures of waste prevention, reduction and recovery. This would help the key stakeholders in driving resource effectiveness, which in turn would assist in conservation of natural resources and prevention of environmental degradation. Copyright © 2015 Elsevier Ltd. All rights reserved.

(La1-xSrx)0.98MnO3 perovskite with A-site deficiencies toward oxygen reduction reaction in aluminum-air batteries

Science.gov (United States)

Xue, Yejian; Miao, He; Sun, Shanshan; Wang, Qin; Li, Shihua; Liu, Zhaoping

2017-02-01

The strontium doped Mn-based perovskites have been proposed as one of the best oxygen reduction reaction catalysts (ORRCs) to substitute the noble metal. However, few studies have investigated the catalytic activities of LSM with the A-site deficiencies. Here, the (La1-xSrx)0.98MnO3 (LSM) perovskites with A-site deficiencies are prepared by a modified solid-liquid method. The structure, morphology, valence state and oxygen adsorption behaviors of these LSM samples are characterized, and their catalytic activities toward ORR are studied by the rotating ring-disk electrode (RRDE) and aluminum-air battery technologies. The results show that the appropriate doping with Sr and introducing A-site stoichiometry can effectively tailor the Mn valence and increase the oxygen adsorption capacity of LSM. Among all the LSM samples in this work, the (La0.7Sr0.3)0.98MnO3 perovskite composited with 50% carbon (50%LSM30) exhibits the best ORR catalytic activity due to the excellent oxygen adsorption capacity. Also, this catalyst has much higher durability than that of commercial 20%Pt/C. Moreover, the maximum power density of the aluminum-air battery using 50%LSM30 as the ORRC can reach 191.3 mW cm-2. Our work indicates that the LSM/C composite catalysts with A-site deficiencies can be used as a promising ORRC in the metal-air batteries.

Os grandes eventos e a cultura em Portugal: sobre os Impactos culturais da Expo’98 e os Públicos do Porto 2001

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Claudino Ferreira

2012-10-01

Full Text Available Os livros em discussão sintetizam os resultados de duas investigações conduzidas pelo Observatório das Actividades Culturais, instituição que tem vindo a desempenhar um papel decisivo na produção de informação e no desenvolvimento da pesquisa sociológica sobre a cultura em Portugal. Os dois trabalhos representam um importante contributo para a compreensão do significado e das implicações culturais dos dois grandes eventos recentemente realizados no nosso país: a Expo’98 e a Porto 2001. Em amb...

Expression, purification, crystallization and preliminary X-ray analysis of maleylacetate reductase from Burkholderia sp. strain SJ98

International Nuclear Information System (INIS)

Chauhan, Archana; Islam, Zeyaul; Jain, Rakesh Kumar; Karthikeyan, Subramanian

2009-01-01

Purification and preliminary X-ray crystallographic analysis of maleylacetate reductase encoded by the pnpD gene is reported. Maleylacetate reductase (EC 1.3.1.32) is an important enzyme that is involved in the degradation pathway of aromatic compounds and catalyzes the reduction of maleylacetate to 3-oxoadipate. The gene pnpD encoding maleylacetate reductase in Burkholderia sp. strain SJ98 was cloned, expressed in Escherichia coli and purified by affinity chromatography. The enzyme was crystallized in both native and SeMet-derivative forms by the sitting-drop vapour-diffusion method using PEG 3350 as a precipitant at 293 K. The crystals belonged to space group P2 1 2 1 2, with unit-cell parameters a = 72.91, b = 85.94, c = 53.07 Å. X-ray diffraction data for the native and SeMet-derivative crystal were collected to 2.7 and 2.9 Å resolution, respectively

Leping kinnisvaraarendaja ja kinnisasja omandaja vahel : kas müügileping või segatüüpi leping? Kommentaar Riigikohtu otsusele tsiviilasjas 3-2-1-98-09 / Karin Sein

Index Scriptorium Estoniae

Sein, Karin, 1974-

2010-01-01

Riigikohtu lahendist 3-2-1-98-09: A & M Invest OÜ kassatsioonkaebus Tallinna Ringkonnakohtu 30.03.2009. a otsusele A & M Invest OÜ hagis K. Radiku ja M. Radiku vastu hüvitise 1 950 946,70 krooni väljamõistmiseks

Wavelet analysis of interannual LOD, AAM, and ENSO: 1997-98 El Niño and 1998-99 La Niña signals

Science.gov (United States)

Zhou, Y. H.; Zheng, D. W.; Liao, X. H.

2001-05-01

On the basis of the data series of the length of day (LOD), the atmospheric angular momentum (AAM) and the Southern Oscillation Index (SOI) for January 1970-June 1999, the relationship among Interannual LOD, AAM, and the EL Niño/Southern Oscillation (ENSO) is analyzed by the wavelet transform method. The results suggest that they have similar time-varying spectral structures. The signals of 1997-98 El Niño and 1998-99 La Niña events can be detected from the LOD or AAM data.

Diagnostiek en behandeling van 39 patiënten met halskliermetastasen van plaveiselcelcarcinoom van onbekende primaire origine, verwezen naar het Nederlands Kanker Instituut/Antoni van Leeuwenhoek Ziekenhuis, 1979/'98

NARCIS (Netherlands)

Klop, W. M.; Balm, A. J.; Keus, R. B.; Hilgers, F. J.; Tan, I. B.

2000-01-01

Evaluation of diagnostic procedures and treatment results in patients with lymph node metastases of squamous cell carcinoma in the head and neck region with an unknown primary. Retrospective, descriptive. In 1979-98, 39 patients (30 male, 9 female; mean age 59 years; range: 39-88) were treated for

Impacto de "El Niño 1997-98" sobre el asentamiento larval de algunos invertebrados marinos bentónicos de bahía Independencia, Pisco -Perú

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Elmer Ramos

2014-06-01

Full Text Available Se evaluó mensualmente los cambios y la magnitud del impacto de "El Niño" (EN, sobre el mecanismo del asentamiento larval de algunos invertebrados marinos bentónicos, en sustratos artificiales filamentosos (fibra nylon, entre enero 1996 y julio 1998, en una estación fija, a 10m de profundidad, situada en el lado oriental de la Isla Independencia, en Bahía Independencia, Durante 1996, en la fase fría "La Niña" (LN, el número de especies presentó un pico en abril y la densidad en junio. En la fase cálida EN 199798, la densidad total y el número de especies, presentaron un primer pico en marzo de 1997, luego, un segundo pico, en febrero y julio de 1998, respectivamente. Un primer grupo de especies que intensificó su asentamiento durante la fase fría LN 1996, estuvo constituido por el bivalvo Hiatella solida, el turbelario Notoplana sp. y el gastrópodo Caecum chilense. El segundo grupo intensificó su asentamiento en la etapa temprana de la fase cálida EN 1997-98, Y lo formaron el braquiópodo Discinisca lamel/osa, el equinodermo Ophíactís kr6yerí y bivalvos de la Familia Mytllidae, Un tercer grupo, mostró una intensificación del asentamiento larval, en la etapa tardía de la fase cálida EN 1997-98, a inicios de 1998, y fue formado por el bivalvo Argopecten purpuratus y un gastrópodo turriforme. La aparición de larvas recién asentadas de especies tropicales, como el bivalvo Ptería stema y el gastrópodo Epitoníum sp., tuvo lugar en la etapa tardía de la fase cálida EN 1997-98.

Valores de aminoácidos digestíveis verdadeiros e equações de predição dos aminoácidos digestíveis do grão e de subprodutos do trigo para aves Values of true digestible amino acids and prediction equations of digestible amino acids of wheat grain and wheat by-products for poultry

Directory of Open Access Journals (Sweden)

Ricardo Vianna Nunes

2001-06-01

Full Text Available Foram determinados os coeficientes de digestibilidade verdadeira dos aminoácidos e elaboradas equações de predição dos valores de aminoácidos digestíveis utilizando a composição química de 11 alimentos. Os alimento avaliados foram: farinha morena, farinha de trigo, trigo-grão, triguilho, gérmen de trigo, resíduo de biscoito, resíduo de macarrão e quatro farelos de trigo. Foi utilizado o método de "alimentação forçada" com galos cecectomizados. O delineamento experimental utilizado foi o inteiramente casualizado, com 11 alimentos e um tratamento-jejum, seis repetições e um galo por unidade experimental. Os coeficientes médios de digestibilidade verdadeira dos aminoácidos para farelo de trigo 1, farelo de trigo 2, farelo de trigo 3, farelo de trigo 4, farinha morena, farinha de trigo, resíduo de biscoito, resíduo de macarrão, trigo-grão, triguilho e gérmen de trigo foram 80,1; 76,7; 71,8; 74,5; 84,1; 94,1; 77,9; 90,1; 86,0; 90,3; e 93,1%, respectivamente. As equações de predição que melhor estimaram os valores de aminoácidos digestíveis verdadeiros foram aquelas que continham os conteúdos de proteína bruta (PB e, ou, extrato etéreo (EE, para o aminoácido lisina, e proteína bruta (PB e, ou, fibra em detergente neutro (FDN, para os aminoácidos metionina, metionina + cistina e treonina e a média dos aminoácidos essenciais, sendo as equações: Lis = -0,8805 + 0,0755*PB + 0,0268*EE (R² = 98%, Met = -0,0377 + 0,0183*PB - 0,0020*FDN (R² = 99%, M+C = 0,0982 + 0,0273*PB - 0,0021*FDN (R² = 92%, Treo = -0,2107 + 0,0401PB - 0,0020*FDN (R² = 96%, Essen = -0,1530 + 0,0451*PB - 0,0024*FDN (R² = 98%.The true digestibility coefficients of amino acids (TDCaa were determined and digestible amino acids prediction equations obtained, using the chemical composition of 11 feedstuffs. The feedstuffs evaluated were: brown flour meal, wheat flour, wheat grain, wheat grain residue, wheat germ, cookies residue, macaroni residue

Using Cherenkov Counting For Fast Determination of 90Sr/90Y Activity in Milk

International Nuclear Information System (INIS)

Tsroya, S.; Dolgin, B.; German, U.; Pelled, O.; Alfassi, Z. B.

2014-01-01

90Sr is one of the main long-lived fission products, and it is transferred into human body primarily by food, with milk being a substantial contributor. Due to its biochemical similarity to calcium, most strontium is efficiently incorporated into bone tissues. 90Sr is characterized by a long physical half life (28.8 y) and decays by beta particles with an Emax of 0.546 MeV to 90Y. This daughter isotope has a half life of 64 h and decays into 90Zr by beta particles with an Emax of 2.284 MeV. The milk components produce a high turbidity and light attenuation, causing a significant decrease of the counting efficiency in liquid scintillation counting (LSC) systems, mostly used for beta emitters detection. Most methods proposed in the past are time-consuming, as they are based on several stages of chemical and physical treatments, including precipitation, ashing, ion exchange and extraction (Wikins et al., 1984, Porter et al, 1961, Kimura et al., 1979). When measuring 90Sr/90Y activity by Cherenkov counting, most of the Cherenkov radiation is produced by 90Y (about 98.6%), due to the much higher energy of its beta particles relative to these from 90Sr. The counting efficiency varies strongly with color quenching, at a greater extent than in standard liquid scintillation counting (L'Annunziata, 2012), and therefore the quench correction is critical. The ‘‘external source area ratio’’ (ESAR) quench correction method was applied to measure 90Sr/90Y activities in aqueous samples with a wide range of quenching levels (Tsroya et al., 2009). This method was proved to be superior to all other quench correction methods (Tsroya et al., 2012) and is applicable also for determination of 90Sr/90Y in human urine (Tsroya et al., 2013). In the present work the applicability of the ESAR method to measurement of 90Sr/90Y activities in milk and some of its products was investigated

Mutagenic activity of 2-(2',4'-diaminophenoxy)ethanol in strains TA1538 and TA98 of Salmonella typhimurium.

Science.gov (United States)

Mohn, G; Bouter, S; de Knijff, P

1982-12-01

The mutagenicity of 2-(2',4'-diaminophenoxy)ethanol (2,4-DAPE) was compared with that of 2,4-diaminoanisole (2,4-DAA), a chemically related compound previously used in hair-dye formulations. Both chemicals were tested in standard procedures with the Salmonella/microsome mutagenicity test as described by Ames and colleagues. In several experiments, which extended over a total period of 2 years, 2,4-DAA exhibited definite, but variable mutagenicity toward strain TA1538 when S9 preparations of rat liver induced with Aroclor 1254 were present in the incubation mixtures. The compound 2,4-DAPE did not exhibit detectable mutagenic activity when tested concomitantly under the same experimental conditions. We conclude that 2,4-DAPE is not mutagenic for Salmonella under conditions of the standard mammalian microsome assay with strain TA1538 and TA98 as indicators.

VALIDACIÓN DE PCR PARA DETECCIÓN DE Listeria monocytogenes EN CARNES CRUDAS DE RES Y POLLO

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Kirvis Torres

2004-12-01

Full Text Available Listeria monocytogenes es un microorganismo zoonótico emergente en la industria de alimentos, resultando degran interés para la salud pública. El objetivo de este trabajo fue validar la técnica de PCR para la detecciónde este microorganismo en carnes crudas de res y pollo. El procedimiento de extracción de ADN fue realizadocon lisozima, proteinasa K y fenol-cloroformo a partir de muestras contaminadas artificialmente. La especificidadde los cebadores LI1 y U1 fue comprobada por la amplificación de una banda de 938pb correspondiente a unfragmento del ADNr 16S; de igual manera los cebadores LF y LR amplificaron una banda del gen hlyA de750pb; lo que permitió la identificación de género (banda 938pb y especie (banda de 750pb respectivamente.Las cepas de los otros géneros bacterianos ensayados no amplificaron ninguna de las bandas específicas. Ellímite de detección para la PCR fue de 102 y 104 UFC/gr para carnes de res y pollo respectivamente; el «GoldStandard» reportó 102 UFC/ml para ambos alimentos. La comparación de la PCR vs., el método «Gold Standard»reportó en carne de pollo una concordancia observada de 98.43%, una sensibilidad del 96.9%, una especificidadde 100%, un valor predictivo positivo del 100% y un valor predictivo negativo del 97%; para la carne de restodos los parámetros anteriores fueron del 100%. Estos resultados demostraron la factibilidad de la PCR parael control de calidad de carnes crudas de res y pollo.

Incidence, prevalence, and mortality of insulin-dependent (type 1) diabetes mellitus in Lithuanian children during 1983-98

DEFF Research Database (Denmark)

Urbonaite, Brone; Zalinkevicius, Rimas; Green, Anders

2002-01-01

-based linear trends of the increase in incidence in various age groups and the annual percentage change for both genders was 2.05 (p = 0.0039) and the greatest regression slope is observed for both genders in the 10-14 yr age group. Regression-based linear trends in type 1 diabetes prevalence indicate an even......AIMS/HYPOTHESIS: Our purpose is to analyze interrelations of the incidence, prevalence and mortality of childhood-onset insulin-dependent diabetes mellitus (type 1) in Lithuania. METHODS: Incidence and prevalence rates were based on the national type 1 diabetes register during 1983-98. The cohort...... study was performed to evaluate the standardized mortality ratios. RESULTS: The average incidence of type 1 diabetes during the 16-yr study period was 7.36 per 100,000/yr. For both males and females the highest incidence of type 1 diabetes was recorded in the 10-14 yr age group. The regression...

Oligocene age of the classic Belén fruit and seed assemblage of north coastal Peru based on diatom biostratigraphy

Science.gov (United States)

Manchester, Steven R.; Herrera, Fabiany; Fourtainer, Elisabeth; Barron, John A.; Martinez, Jean-Noël

2012-01-01

The Belén flora, in north coastal Peru, is the most diverse fruit and seed assemblage known from the Paleogene of South America. Almost no original paleobotanical work has been done on this assemblage since the pioneering treatments published by E.W. Berry, in the 1920’s and the precise age has not been settled. Nevertheless, the flora has been regarded as an important focal point in understanding the vegetational, orogenic and climatic history of northern South America, and in recent literature has been assumed to be early Eocene. In order to tighten the age assignment, which has varied from early Eocene to early Oligocene in the opinions of different authors, we revisited the Belén site, measured the stratigraphic section, and processed the fruit and seed-containing sediment for age-diagnostic microfossils. Although pollen and foraminifera were not recovered, the sediment is rich in diatoms. The diatom assemblage includes Lisitzinia ornata and Rocella vigilans among others, indicating a latest early Oligocene age (~30-28.5 Ma) for these deeper marine sediments that we infer to have been subsequently reworked into the Belén environment . This association leads us to consider the Belén flora, to be late Oligocene in age as is also consistent with its placement in the Mancora Formation. We also reevaluate the botanical identifications, based on the original museum specimens supplemented by more recently collected specimens. The Belén flora provides a window to extinct forests in South America before the rising of the Andes in western Peru.

The museum as heritage, the republic as memory:art and colleting in Belém do Pará (1890-1940

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Aldrin Moura de Figueiredo

2014-12-01

Full Text Available This article analyze the art collection of Museu de Arte de Belém as historical and cultural heritage of the city of Belém, State of Pará, Brazil. This collection also initiated in the Empire of Brazil, was strengthened during the early Republic as part of a political exercise that took the art and history as formative elements of nationality.

Framework for a Risk-Informed Groundwater Compliance Strategy for Corrective Action Unit 98: Frenchman Flat, Nevada National Security Site, Nye County, Nevada, Revision 1

Energy Technology Data Exchange (ETDEWEB)

Marutzky, Sam

2010-09-01

Note: This document was prepared before the NTS was renamed the Nevada National Security Site (August 23, 2010); thus, all references to the site herein remain NTS. Corrective Action Unit (CAU) 98, Frenchman Flat, at the Nevada Test Site (NTS) was the location of ten underground nuclear tests between 1965 and 1971. As a result, radionuclides were released in the subsurface in the vicinity of the test cavities. Corrective Action Unit 98 and other CAUs at the NTS and offsite locations are being investigated. The Frenchman Flat CAU is one of five Underground Test Area (UGTA) CAUs at the NTS that are being evaluated as potential sources of local or regional impact to groundwater resources. For UGTA sites, including Frenchman Flat, contamination in and around the test cavities will not be remediated because it is technologically infeasible due to the depth of the test cavities (150 to 2,000 feet [ft] below ground surface) and the volume of contaminated groundwater at widely dispersed locations on the NTS. Instead, the compliance strategy for these sites is to model contaminant flow and transport, estimate the maximum spatial extent and volume of contaminated groundwater (over a period of 1,000 years), maintain institutional controls, and restrict access to potentially contaminated groundwater at areas where contaminants could migrate beyond the NTS boundaries.

Underground Test Area (UGTA) Closure Report for Corrective Action Unit 98: Frenchman Flat Nevada National Security Site, Nevada, Revision 1 ROTC-1

International Nuclear Information System (INIS)

Farnham, Irene

2016-01-01

This Closure Report (CR) has been prepared for Corrective Action Unit (CAU) 98, Frenchman Flat, Nevada National Security Site (NNSS), Nevada. The Frenchman Flat CAU was the site of 10 underground nuclear tests, some of which have impacted groundwater near the tests. This work was performed as part of the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) Underground Test Area (UGTA) Activity in accordance with the Federal Facility Agreement and Consent Order (FFACO). This CR describes the selected corrective action to be implemented during closure to protect human health and the environment from the impacted groundwater

Underground Test Area (UGTA) Closure Report for Corrective Action Unit 98: Frenchman Flat Nevada National Security Site, Nevada, Revision 1 ROTC-1

Energy Technology Data Exchange (ETDEWEB)

Farnham, Irene [Navarro-Intera, LLC (N-I), Las Vegas, NV (United States)

2016-08-01

This Closure Report (CR) has been prepared for Corrective Action Unit (CAU) 98, Frenchman Flat, Nevada National Security Site (NNSS), Nevada. The Frenchman Flat CAU was the site of 10 underground nuclear tests, some of which have impacted groundwater near the tests. This work was performed as part of the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) Underground Test Area (UGTA) Activity in accordance with the Federal Facility Agreement and Consent Order (FFACO). This CR describes the selected corrective action to be implemented during closure to protect human health and the environment from the impacted groundwater

On interrelations of Sr90 contents in the soil-forage plants-milk chain under natural conditions

International Nuclear Information System (INIS)

Chupka, Sh.

1975-01-01

Observations were made on 150 soil damples, 58 plant root samples, and 98 milk samples. Four types of soil from western Slovakia (chernozem, brown, sandy, and carbonate) and two types of plant roots (alfalfa and mixed grasses) were studied. A relation was shown between the type of soil, its physico-chemical properties, the Sr 90 accumulation in the plant roots, and the degree of contamination of milk by this radionuclide. (V.A.P.)

Dining in the lions� den � Bel and the dragon, verses 28�42 (Old Greek/Theodotion

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Joseph J. de Bruyn

2015-03-01

Full Text Available This article is part of a series of articles written on Bel and the dragon. This series of articles is an investigation into the Greek editor/author�s use of body, space, narrative and genre in creating a new reality regarding the Jewish deity. A spatial framework is used to specifically examine the third episode of Bel and the dragon, entitled Dining in the lions� den. It is suggested that the third episode of Bel and the dragon should be read in a reciprocal relationship with not only Bel and the dragon but also the larger book of Daniel. Firstly, such an analysis indicates that the smaller episode is part of a larger clash of deities. Secondly, it shows that the editor/ author utilises the episode to recreate a new cosmology. In this new cosmology, the God of Israel is an almighty deity whilst other deities are revealed as false and not real living gods. In his own way, the editor/author contributes to the way in which Jews regarded their God within the reality of the diaspora.Intradisciplinary and/or interdisciplinary implications: The aim with this article was to analyse Daniel 14 by means of new insights from developments in language studies. Until now, scholars tended to repeat each other in their analysis of Daniel 14. No attention was given to space, body or other aspects of new developments in the field of language. This article challenges the repetitive research previously done on Daniel 14.

El Niño 1997-98 en los medios de comunicación: realidades, deformaciones y exageraciones de un evento climático

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Óscar Marcos Valiente

2000-01-01

Full Text Available El fenómeno El Niño de 1997-98 ha sobrepasado su dimensión climática y ha adquirido una repercusión mediática sin precedentes, tomando temporalmente el relevo a otras preocupaciones medioambientales como el cambio climático o el agujero de la capa de ozono. Este artículo revisa el tratamiento informativo del evento, y ofrece una recopilación de curiosidades y equívocos relacionados con El Niño aparecidos en medios de comunicación

スウェーデンの就学前学校のLäroplan för förskolan 98における音楽の意義 : 生涯学習を中心に

OpenAIRE

松本, 進乃助

2016-01-01

This study examines music education in Swedish preschools. Swedish preschool education is based on the concept of life-long learning. In Sweden, the pattern for life-long learning in preschool takes the form of inculcating the desire to learn among young children. The Läroplan för förskolan 98 (Lpfö98) makes the following statements with respect to music: “Creating and communicating by means of different forms of expression, such as pictures, song and music, drama, rhythm, dance and movement,...

Physical activity patterns and socioeconomic position: the German National Health Interview and Examination Survey 1998 (GNHIES98).

Science.gov (United States)

Finger, Jonas D; Tylleskär, Thorkild; Lampert, Thomas; Mensink, Gert B M

2012-12-15

We investigated the associations between education and leisure-time, occupational, sedentary and total physical-activity levels based on data from the German National Health Interview and Examination Survey 1998 (GNHIES98). The roles of income level, occupational status and other mediating variables for these associations were also examined. The total study sample of the GNHIES98 comprised 7,124 participants between the ages of 18 and 79. Complete information was available for 6,800 persons on leisure-time, sedentary and total physical-activity outcomes and for 3,809 persons in regular employment on occupational activity outcomes. The associations between educational level and physical activity (occupational, sedentary, leisure-time and total physical activity) were analysed separately for men and women using multivariate logistic regression analysis. Odds ratios (OR) of educational level on physical-activity outcomes were calculated and adjusted for age, region, occupation, income and other mediating variables. After adjusting for age and region, a higher education level was associated with more leisure-time activity - with an OR of 1.6 (95% CI, 1.3-2.0) for men with secondary education and 2.1 (1.7-2.7) for men with tertiary education compared to men with primary education. The corresponding ORs for women were 1.3 (1.1-1.6) and 1.7 (1.2-2.4), respectively. Higher education was associated with a lower level of vigorous work activity: an OR of 6.9 (4.6-10.3) for men with secondary education and 18.6 (12.0-27.3) for men with primary education compared to men with tertiary education. The corresponding ORs for women were 2.8 (2.0-4.0) and 5.8 (4.0-8.5), respectively. Higher education was also associated with a lower level of total activity: an OR of 2.9 (2.2-3.8) for men with secondary education and 4.3 (3.3-5.6) for men with tertiary education compared to men with primary education. The corresponding ORs for women were 1.6 (1.2-2.0) and 1.6 (1.2-2.1), respectively

Effectiveness of Balancing Everyday Life (BEL) versus standard occupational therapy for activity engagement and functioning among people with mental illness - a cluster RCT study.

Science.gov (United States)

Eklund, Mona; Tjörnstrand, Carina; Sandlund, Mikael; Argentzell, Elisabeth

2017-11-09

Many with a mental illness have an impoverished everyday life with few meaningful activities and a sedentary lifestyle. The study aim was to evaluate the effectiveness of the 16-week Balancing Everyday Life (BEL) program, compared to care as usual (CAU), for people with mental illness in specialized and community-based psychiatric services. The main outcomes concerned different aspects of subjectively evaluated everyday activities, in terms of the engagement and satisfaction they bring, balance among activities, and activity level. Secondary outcomes pertained to various facets of well-being and functioning. It was hypothesized that those who received the BEL intervention would improve more than the comparison group regarding activity, well-being and functioning outcomes. BEL is a group and activity-based lifestyle intervention. CAU entailed active support, mainly standard occupational therapy. The BEL group included 133 participants and the CAU group 93. They completed self-report questionnaires targeting activity and well-being on three occasions - at baseline, after completed intervention (at 16 weeks) and at a six-month follow-up. A research assistant rated the participants' level of functioning and symptom severity on the same occasions. Non-parametric statistics were used since these instruments produced ordinal data. The BEL group improved more than the CAU group from baseline to 16 weeks on primary outcomes in terms of activity engagement (p life) more than the CAU group from baseline to the follow-up (p = 0.049). No differences were found at that time for activity balance, level of functioning and symptom severity. The BEL program was effective compared to CAU in terms of activity engagement. Their improvements were not, however, greater concerning other subjective perceptions, such as satisfaction with daily activities and self-rated health, and clustering effects lowered the dependability regarding findings of improvements on symptoms and

Symptoms of endocrine treatment and outcome in the BIG 1-98 study.

Science.gov (United States)

Huober, J; Cole, B F; Rabaglio, M; Giobbie-Hurder, A; Wu, J; Ejlertsen, B; Bonnefoi, H; Forbes, J F; Neven, P; Láng, I; Smith, I; Wardley, A; Price, K N; Goldhirsch, A; Coates, A S; Colleoni, M; Gelber, R D; Thürlimann, B

2014-01-01

There may be a relationship between the incidence of vasomotor and arthralgia/myalgia symptoms and treatment outcomes for postmenopausal breast cancer patients with endocrine-responsive disease who received adjuvant letrozole or tamoxifen. Data on patients randomized into the monotherapy arms of the BIG 1-98 clinical trial who did not have either vasomotor or arthralgia/myalgia/carpal tunnel (AMC) symptoms reported at baseline, started protocol treatment and were alive and disease-free at the 3-month landmark (n = 4,798) and at the 12-month landmark (n = 4,682) were used for this report. Cohorts of patients with vasomotor symptoms, AMC symptoms, neither, or both were defined at both 3 and 12 months from randomization. Landmark analyses were performed for disease-free survival (DFS) and for breast cancer free interval (BCFI), using regression analysis to estimate hazard ratios (HR) and 95 % confidence intervals (CI). Median follow-up was 7.0 years. Reporting of AMC symptoms was associated with better outcome for both the 3- and 12-month landmark analyses [e.g., 12-month landmark, HR (95 % CI) for DFS = 0.65 (0.49-0.87), and for BCFI = 0.70 (0.49-0.99)]. By contrast, reporting of vasomotor symptoms was less clearly associated with DFS [12-month DFS HR (95 % CI) = 0.82 (0.70-0.96)] and BCFI (12-month DFS HR (95 % CI) = 0.97 (0.80-1.18). Interaction tests indicated no effect of treatment group on associations between symptoms and outcomes. While reporting of AMC symptoms was clearly associated with better DFS and BCFI, the association between vasomotor symptoms and outcome was less clear, especially with respect to breast cancer-related events.

Caracterização química do resíduo do processamento agroindustrial da manga (Mangifera indica L. var. Ubá
Chemical characterization of agroindustrial residue of mango (Mangifera indica L. variety Ubá

Directory of Open Access Journals (Sweden)

P. A. F. VIEIRA

2010-05-01

Full Text Available

Após o processamento industrial da manga, suas sementes e cascas são descartadas, representando até 60% do peso total da fruta e gerando grande quantidade de resíduos. O objetivo do presente trabalho foi caracterizar os resíduos industriais provenientes do processo de esmagamento da manga (Mangifera indica L. var. Ubá para a obtenção do suco. As sementes e cascas obtidas foram submetidas à secagem a 60ºC/72 horas e trituradas. As amêndoas retiradas das sementes secas também foramtrituradas. Os farelos da amêndoa, da semente e do resíduo total (cascas e sementes foram analisados para determinação dos teores de matéria seca, proteína bruta, fi bra detergente neutro, fi bra detergente ácido, fi bra bruta, lignina (somente do farelo da amêndoa, extrato etéreo, matéria mineral, cálcio, fósforo e carboidratos totais por diferença. Os resultados obtidos para o farelo da amêndoa foram: 88,36%, 4,39%, 29,65%, 2,20%, 1,90%, 0,72%, 12,18%, 1,81%, 0,10%, 0,05% e 69,98%. Para o resíduo total os resultados foram: 92,23%, 3,87%, 37,25%, 21,84%, 14,60%, 4,36%, 2,08%, 0,18%, 0,11% e 81,92%, respectivamente. O óleo da amêndoa da semente apresentou elevado teor dos ácidos oléico (43,71%, linoléico (9% e esteárico (39,79%, com índice de saponifi cação de 176,6. Sendo assim, este resíduo foi caracterizado como um ingrediente com potencial para ser aproveitado tanto na alimentação animal como humana.

Half-life evaluations for 3H, 90Sr, and 90Y

International Nuclear Information System (INIS)

MacMahon, Desmond

2006-01-01

A recent paper has reviewed methods for the evaluation of discrepant sets of data and demonstrated the results of applying these methods to the published half-life data of 90 Sr and 137 Cs [MacMahon, T.D., Pearce, A., Harris, P., 2004. Convergence of techniques for the evaluation of discrepant data. Appl. Radiat. Isot. 60, 275-281]. The half-life data for 3 H has been subject to a comprehensive review and critical evaluation by Lucas and Unterweger [2000. Comprehensive review and critical evaluation of the half-life of tritium. J. Res. Natl. Inst. Stand. Technol. 105, 541-549]. The current paper reports the results of applying the various evaluation procedures of MacMahon et al. Convergence of techniques for the evaluation of discrepant data. Appl. Radiat. Isot. 60, 275-281] to the data of Lucas and Unterweger [Comprehensive review and critical evaluation of the half-life of tritium. J. Res. Natl. Inst. Stand. Technol. 105, 541-549], resulting in a recommended half-life of 4497(4) days. MacMahon et al. [Convergence of techniques for the evaluation of discrepant data. Appl. Radiat. Isot. 60, 275-281] highlighted problems in the evaluation of the discrepant half-life data of 90 Sr, in particular the worrying upward trend in the data, where the weighted mean of all the measurements increases, on average, by 35 days each time a new measurement result is added. The current paper reports on further analyses of these data. New measurements of the half-life of 90 Y have been reported by Kossert and Schrader [2004. Standardization by liquid scintillation counting and half-life measurements of 90 Y. Appl. Radiat. Isot. 60, 741]. This has prompted a new evaluation of all available published 90 Y half-life data. The data are fairly consistent, and a value of 64.063(16) h is recommended

Non-homologous end joining mediated DNA repair is impaired in the NUP98-HOXD13 mouse model for myelodysplastic syndrome.

Science.gov (United States)

Puthiyaveetil, Abdul Gafoor; Reilly, Christopher M; Pardee, Timothy S; Caudell, David L

2013-01-01

Chromosomal translocations typically impair cell differentiation and often require secondary mutations for malignant transformation. However, the role of a primary translocation in the development of collaborating mutations is debatable. To delineate the role of leukemic translocation NUP98-HOXD13 (NHD13) in secondary mutagenesis, DNA break and repair mechanisms in stimulated mouse B lymphocytes expressing NHD13 were analyzed. Our results showed significantly reduced expression of non-homologous end joining (NHEJ)-mediated DNA repair genes, DNA Pkcs, DNA ligase4, and Xrcc4 leading to cell cycle arrest at G2/M phase. Our results showed that expression of NHD13 fusion gene resulted in impaired NHEJ-mediated DNA break repair. Copyright © 2012 Elsevier Ltd. All rights reserved.

School-based study found that physical activity and aerobic fitness predicted increases in total body fat and abdominal fat at a mean age of 9.8 years.

Science.gov (United States)

Danielson, Anton; Thorsson, Ola; Karlsson, Magnus K; Wollmer, Per; Andersen, Lars B; Dencker, Magnus

2018-02-22

We assessed whether baseline measurements of physical activity, aerobic fitness, body fat and abdominal fat were predictors of changes in body fat measurements over a two-year period. The study comprised of 204 children aged 9.8 ± 0.6 years with a normal body mass distribution, who recruited from four schools in middle-class areas of Malmö, Sweden, from 2001 to 2004. Peak oxygen uptake and physical activity were measured at baseline. Body fat was measured by dual-energy X-ray absorptiometry at baseline and two years later. Physical activity, aerobic fitness and total body fat or abdominal fat were predictors of change in total body fat or abdominal fat over a period of two years. Changes in the percentage of body fat were not related to any of the baseline measurements. Our two-year follow-up of children with a mean age of 9.8 years at baseline showed that physical activity, aerobic fitness and body fat or abdominal fat predicted changes in total body fat or abdominal fat, but not the percentage of body fat. ©2018 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Overall survival benefit for sequential doxorubicin-docetaxel compared with concurrent doxorubicin and docetaxel in node-positive breast cancer--8-year results of the Breast International Group 02-98 phase III trial

DEFF Research Database (Denmark)

Oakman, C; Francis, P A; Crown, J

2013-01-01

Background In women with node-positive breast cancer, the Breast International Group (BIG) 02-98 tested the incorporation of docetaxel (Taxotere) into doxorubicin (Adriamycin)-based chemotherapy, and compared sequential and concurrent docetaxel. At 5 years, there was a trend for improved disease...

Radiolabeling Of Albumin Particles With Yttrium-90

International Nuclear Information System (INIS)

Nguyen Thi Thu; Nguyen Thi Khanh Giang; Bui Van Cuong, Vo Thi Cam Hoa

2011-01-01

This paper presents the process of the radiolabeling of microaggregated albumin particles with radionuclide Yttrium-90 using the directed method. The albumin microsphere kit was prepared in sodium phosphate buffer. The original solution includes 2 mg albumin particle and 0.5 mg stannous chloride dihydrate. The albumin particles size was ranged from 5 ?m to 30 ?m. The mixture was washed three times with phosphate buffer saline, pH 7.2 by centrifugation and suspended in 0.5 M sodium acetate buffer, pH 6. Yttrium - 90 in 1.0 M acetic acid was collected from 90 Sr/ 90 Y generator. The labeling of the particles with Y-90 (185 MBq) was performed at pH 5.5 in acetate buffer with agitating for 60 min at room temperature. The labeled albumin suspensions were centrifuged at 3000 rpm for 15 min. Labeling yields was calculated using centrifugation, filtration and compared with paper chromatography, which is developed in the Tris Acetic EDTA. In this system, the unbound of Y-90 migrates to an R f of 0.9-1.0 and the radiolabeled albumin particles remains at the point of origin (R f = 0). The size of 90 Y-albumin particles was compared with the albumin particles in the original solution to be sure that they did not change during the labeling treatment. The radiolabeling yields were more than 80%. The labeled compound was dialysis in phosphate buffer. The radiochemical purity was 98%. The 90 Y- albumin is an ideal radiopharmaceutical for potential use in malignant cancer treatment as brachytherapy. (author)