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Sample records for bel82 bel90 res98

  1. Belöning och motivation

    OpenAIRE

    Blomqvist, Johnny

    2015-01-01

    Många företag använder sig av belöningssystem för att hålla kvar den nuvarande personalen och för att motivera personalen till ett bättre resultat i framtiden. För att ett belöningssystem skall fungera måste personalen vara motiverade. Syftet med detta arbete är att utreda vad personalen i några företag på Kimitoön anser om belöning och betydelsen av belöning i arbetet. I undersökningen utreder jag även motivationens betydelse i arbetet och vilken typ av belöning som motiverar på längre si...

  2. The BEL information extraction workflow (BELIEF): evaluation in the BioCreative V BEL and IAT track.

    Science.gov (United States)

    Madan, Sumit; Hodapp, Sven; Senger, Philipp; Ansari, Sam; Szostak, Justyna; Hoeng, Julia; Peitsch, Manuel; Fluck, Juliane

    2016-01-01

    Network-based approaches have become extremely important in systems biology to achieve a better understanding of biological mechanisms. For network representation, the Biological Expression Language (BEL) is well designed to collate findings from the scientific literature into biological network models. To facilitate encoding and biocuration of such findings in BEL, a BEL Information Extraction Workflow (BELIEF) was developed. BELIEF provides a web-based curation interface, the BELIEF Dashboard, that incorporates text mining techniques to support the biocurator in the generation of BEL networks. The underlying UIMA-based text mining pipeline (BELIEF Pipeline) uses several named entity recognition processes and relationship extraction methods to detect concepts and BEL relationships in literature. The BELIEF Dashboard allows easy curation of the automatically generated BEL statements and their context annotations. Resulting BEL statements and their context annotations can be syntactically and semantically verified to ensure consistency in the BEL network. In summary, the workflow supports experts in different stages of systems biology network building. Based on the BioCreative V BEL track evaluation, we show that the BELIEF Pipeline automatically extracts relationships with an F-score of 36.4% and fully correct statements can be obtained with an F-score of 30.8%. Participation in the BioCreative V Interactive task (IAT) track with BELIEF revealed a systems usability scale (SUS) of 67. Considering the complexity of the task for new users-learning BEL, working with a completely new interface, and performing complex curation-a score so close to the overall SUS average highlights the usability of BELIEF.Database URL: BELIEF is available at http://www.scaiview.com/belief/. © The Author(s) 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. 10 Bel 03.pmd

    African Journals Online (AJOL)

    Owner

    2 maart 2009 ... Congo, de missie en de literatuur: Over David van Reybrouck,. J. G. Schoup en Amaat Vyncke. Jacqueline Bel. Jacqueline Bel is als universitair hoofddocent moderne Nederlandse letterkunde verbonden aan de Vrije. Universiteit in Amsterdam. Zij is onder meer gespecialiseerd in Nederlandse en Vlaamse.

  4. The BEL information extraction workflow (BELIEF): evaluation in the BioCreative V BEL and IAT track

    OpenAIRE

    Madan, Sumit; Hodapp, Sven; Senger, Philipp; Ansari, Sam; Szostak, Justyna; Hoeng, Julia; Peitsch, Manuel; Fluck, Juliane

    2016-01-01

    Network-based approaches have become extremely important in systems biology to achieve a better understanding of biological mechanisms. For network representation, the Biological Expression Language (BEL) is well designed to collate findings from the scientific literature into biological network models. To facilitate encoding and biocuration of such findings in BEL, a BEL Information Extraction Workflow (BELIEF) was developed. BELIEF provides a web-based curation interface, the BELIEF Dashboa...

  5. Indoor and outdoor genotoxic load detected by the Comet assay in leaves of Nicotiana tabacum cultivars Bel B and Bel W3.

    Science.gov (United States)

    Restivo, Francesco Maria; Laccone, Maria Concetta; Buschini, Annamaria; Rossi, Carlo; Poli, Paola

    2002-03-01

    Environmental pollution assessment and control are priority issues for both developed and developing countries of the world. The use of plant material for a more complete picture of environmental health appears to be particularly appealing. Here we validate a previous plant-adapted Comet assay on leaf tissues of Nicotiana tabacum cultivars Bel B and Bel W3. The effects of H(2)O(2) on DNA damage in Bel B and Bel W3 agree with the hypothesis that some component of the machinery that protects DNA integrity from oxidative stress may be impaired in cv. Bel W3. Exposure in the field on sunny summer days (peak ozone concentration >80 p.p.b.) showed significantly higher DNA damage in cv. Bel W3 if plants were collected and subjected to the Comet assay when the air ozone concentration was reaching its peak value, but not when plants were sampled early in the morning and hence after a period of low ozone concentration. The different results suggest that Bel W3 possesses a less efficient recovery apparatus that requires a longer period of activity to be effective and/or is less protected against reactive oxygen species production during exposure to ozone. However, it cannot be excluded that the increase in mean DNA damage is the result of the presence of a genotoxic agent(s) other than ozone. Interestingly, Bel W3 also appears to be more responsive, compared with Bel B, when exposed to ambient indoor pollutants. The use of cv. Bel W3 increases the sensitivity of the assay under both indoor and field conditions. However, different classes of mutagens should be tested to define the range of profitable utilization of this tobacco cultivar for environmental genotoxicity detection.

  6. Sexuelle Belästigung aus strafrechtlicher Sicht

    Directory of Open Access Journals (Sweden)

    Maria Eder-Rieder

    2004-07-01

    Full Text Available Der Kern der Arbeit ist die juristische Aufarbeitung der Grenzen und Reichweite der in der Schweiz seit 1. Oktober 1992 in Kraft befindlichen Regelungen zur sexuellen Belästigung durch Vornahme einer sexuellen Handlung vor jemanden (Art. 198 Abs. 1 StGB, der tätlichen sexuellen Belästigung und der verbalen Belästigung (Art. 198 Abs. 2 StGB. Diese Tatbestände werden anhand von Beispielen erläutert, mit weiteren Varianten der sexuellen Belästigung verglichen und zu anderen Tatbeständen abgegrenzt. Ebenso wird auf das Verhältnis zum Zivilrecht und die Problematik des Strafprozesses eingegangen. Abschließend wird der kriminalpolitischen Frage über den Sinn der strafrechtlichen Sanktionierung nachgegangen.

  7. Fugemateriale til belægningssten og fliser

    DEFF Research Database (Denmark)

    Larsen, Kristian

    2004-01-01

    Der anlægges ca. 9 millioner kvadratmeter belægning i betonsten og fliser om året i Danmark. Fugearealet udgør gennemsnitlig 4 %, svarende til et areal på ca. 36 ha.......Der anlægges ca. 9 millioner kvadratmeter belægning i betonsten og fliser om året i Danmark. Fugearealet udgør gennemsnitlig 4 %, svarende til et areal på ca. 36 ha....

  8. Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells

    International Nuclear Information System (INIS)

    Hou, Y.; Chu, M.; Du, F.F.; Lei, J.Y.; Chen, Y.; Zhu, R.Y.; Gong, X.H.; Ma, X.; Jin, J.

    2013-01-01

    Highlights: •rhddADAM15 inhibited the proliferation and migration of Bel-7402 cells. •rhddADAM15 inhibited growth and metastasis of Bel-7402 cells in zebrafish xenograft. •rhddADAM15 induced apoptosis in Bel-7402 cells and somatic cells of zebrafish. •Cell-cycle in Bel-7402 cells showed a partial G 2 /S arrest. •Activity of caspases 8, 9 and 3 was increased in rhddADAM15-treated Bel-7402 cells. -- Abstract: ADAM15 (A Disintegrin And Metalloproteinase 15), a transmembrane protein containing seven domains, interacts with some integrins via its disintegrin domain and overexpresses in many solid tumors. In this study, the effect of the recombinant human disintegrin domain (rhddADAM15) on the proliferation and migration of Bel-7402 cells was evaluated in vitro and in vivo in zebrafish xenografts. rhddADAM15 (4 μM) severely inhibited the proliferation and migration of Bel-7402 cells, inducing a partial G 2 /S arrest and morphological nucleus changes of apoptosis. Moreover, the activity of caspases 8, 9 and 3 in Bel-7402 cells was increased. In addition, the zebrafish was used as a model for apoptosis-induction and tumor-xenograft. rhddADAM15 (1 pM) inhibited the growth and metastasis of Bel-7402 cell xenografts in zebrafish and a lower concentration (0.1 pM) induced severe apoptosis in the somatic cells of zebrafish. In conclusion, our data identified rhddADAM15 as a potent inhibitor of tumor growth and metastasis, making it a promising tool for use in anticancer treatment

  9. Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Y. [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China); Chu, M. [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Medicine, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China); Du, F.F.; Lei, J.Y.; Chen, Y.; Zhu, R.Y.; Gong, X.H.; Ma, X. [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China); Jin, J., E-mail: jinjian31@126.com [Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, 1800 Lihu Rd., Wuxi, Jiangsu 214122 (China)

    2013-06-14

    Highlights: •rhddADAM15 inhibited the proliferation and migration of Bel-7402 cells. •rhddADAM15 inhibited growth and metastasis of Bel-7402 cells in zebrafish xenograft. •rhddADAM15 induced apoptosis in Bel-7402 cells and somatic cells of zebrafish. •Cell-cycle in Bel-7402 cells showed a partial G{sub 2}/S arrest. •Activity of caspases 8, 9 and 3 was increased in rhddADAM15-treated Bel-7402 cells. -- Abstract: ADAM15 (A Disintegrin And Metalloproteinase 15), a transmembrane protein containing seven domains, interacts with some integrins via its disintegrin domain and overexpresses in many solid tumors. In this study, the effect of the recombinant human disintegrin domain (rhddADAM15) on the proliferation and migration of Bel-7402 cells was evaluated in vitro and in vivo in zebrafish xenografts. rhddADAM15 (4 μM) severely inhibited the proliferation and migration of Bel-7402 cells, inducing a partial G{sub 2}/S arrest and morphological nucleus changes of apoptosis. Moreover, the activity of caspases 8, 9 and 3 in Bel-7402 cells was increased. In addition, the zebrafish was used as a model for apoptosis-induction and tumor-xenograft. rhddADAM15 (1 pM) inhibited the growth and metastasis of Bel-7402 cell xenografts in zebrafish and a lower concentration (0.1 pM) induced severe apoptosis in the somatic cells of zebrafish. In conclusion, our data identified rhddADAM15 as a potent inhibitor of tumor growth and metastasis, making it a promising tool for use in anticancer treatment.

  10. Comparison of the multi-drug resistant human hepatocellular carcinoma cell line Bel-7402/ADM model established by three methods

    Directory of Open Access Journals (Sweden)

    Zhong Xingguo

    2010-08-01

    Full Text Available Abstract Background To compare the biological characteristics of three types of human hepatocellular carcinoma multi-drug resistant cell sub-lines Bel-7402/ADM models established by three methods. Methods Established human hepatocellular carcinoma adriamycin (ADM multi-drug resistant cell sub-lines models Bel-7402/ADMV, Bel-7402/ADML and Bel-7402/ADMS by three methods of in vitro concentration gradient increased induction, nude mice liver-implanted induction and subcutaneous-implanted induction respectively. Phase contrast microscopy was used to observe the cells and the MTT (methyl thiazolyl tetrazolium method was used to detect drug resistance of the three different sub-lines of cells. Results The three groups of drug resistant cells, Bel-7402/ADMV, Bel-7402/ADML and Bel-7402/ADMS generated cross-resistance to ADM and CDDP (cis-Diaminedichloroplatinum, but showed a significant difference in resistance to Bel-7402 IC50 value (P V, 46 h (Bel-7402/ADML, and 45 h (Bel-7402/ADMS. The excretion rates of ADM were significantly increased compared with the parent cell (34.14% line and were 81.06% (Bel-7402/ADMV, 66.56% (Bel-7402/ADML and 61.56% (Bel-7402/ADMS. Expression of P-gp and MRP in the three groups of resistant cells was significantly enhanced (P P > 0.05. Conclusions Stable resistance was involved in the resistant cell line model established by the above three methods. Liver implantation was a good simulation of human hepatocellular and proved to be an ideal model with characteristics similar to human hepatocellular biology and the pharmacokinetics of anticancer drugs.

  11. Bel-Robinson energy and the nature of singularities in isotropic cosmologies

    International Nuclear Information System (INIS)

    Klaoudatou, Ifigeneia; Cotsakis, Spiros

    2007-01-01

    We review our recent work on the classification of finite time singularities that arise in isotropic universes. This scheme is based on the exploitation of the Bel Robinson energy in a cosmological setting. We comment on the relation between geodesic completeness and the Bel Robinson energy and present evidence that relates the divergence of the latter to the existence of closed trapped surfaces

  12. Cell suspension culture-mediated incorporation of the rice bel gene into transgenic cotton.

    Directory of Open Access Journals (Sweden)

    Liping Ke

    Full Text Available Cotton plants engineered for resistance to the herbicides, glyphosate or glufosinate have made a considerable impact on the production of the crop worldwide. In this work, embryogenic cell cultures derived from Gossypium hirsutum L. cv Coker 312 hypocotyl callus were transformed via Agrobacterium tumefaciens with the rice cytochrome P450 gene, CYP81A6 (bel. In rice, bel has been shown to confer resistance to both bentazon and sulfanylurea herbicides. Transformed cells were selected on a liquid medium supplemented alternately or simultaneously with kanamycin (50mg/L and bentazon (4.2 µmol. A total of 17 transgenic cotton lines were recovered, based on the initial resistance to bentazon and on PCR detection of the bel transgene. Bel integration into the cotton genome was confirmed by Southern blot and expression of the transgene was verified by RT-PCR. In greenhouse and experimental plot trials, herbicide (bentazon tolerance of up to 1250 mg/L was demonstrated in the transgenic plants. Transgenic lines with a single copy of the bel gene showed normal Mendelian inheritance of the characteristic. Importantly, resistance to bentazon was shown to be stably incorporated in the T1, T2 and T3 generations of self-fertilised descendents and in plants outcrossed to another upland cotton cultivar. Engineering resistance to bentazon in cotton through the heterologous expression of bel opens the possibility of incorporating this trait into elite cultivars, a strategy that would give growers a more flexible alternative to weed management in cotton crops.

  13. OF THE GREAT TEMPLE OF BEL

    Directory of Open Access Journals (Sweden)

    A. Denker

    2017-02-01

    Full Text Available The Great Temple of Bel in Palmyra was a unique edifice which had blended the well established lines of Greco-Roman architecture with the art and taste of the Orient. With the gilded bronze capitals of its 41 Corinthian columns it was the product of enormous effort and budget. It was the gem of a remarkable epoch of wealthy Palmyra and mighty Roma. With its splendidly decorated adyta ceilings it became a source of inspiration and imagination for Western architecture and decorative arts. While continuing to captivate the World, it was leveled and vanished as a grim result of conflict based vandalism. The aim of this work is to piece together this, the most eloquent and stupendous monument of the Roman East, from its ruins and reconstruct it as it was once extant. Its loss is irreplacable, but its photo-realistic reconstruction can offer some solace by waking the memories of the great temple as in the past. The lost reality of the Great Temple of Bel is revived here by digitally constructing its “ghost images".

  14. Early Musical Training in Bel Canto Vocal Technique: A Brief History and Philosophy.

    Science.gov (United States)

    Gerstein, Christine Wondolowski

    This paper offers a brief history and philosophy of the origins of bel canto vocal style and describes the pedagogical methods used to achieve bel canto ideals in singing. The document discusses the adoption and development of this technique and how it developed over long periods of preparation in the foregoing centuries before the Baroque era.…

  15. Daniel Dragonslayer – Bel and the dragon, Verses 23−27 (OG/Th

    Directory of Open Access Journals (Sweden)

    Joseph J. de Bruyn

    2015-04-01

    Full Text Available In this article, aspects of narrative critique, genre, editorial critique, the body and space are uniquely combined into a body-space framework. This spatial framework is used to examine the second episode of ‘Bel and the Dragon’, called ‘Daniel Dragonslayer’. It is postulated that the second episode of ‘Bel and the Dragon’ should be read in a reciprocal relationship with not only ‘Bel and the Dragon’, but also the larger Book of Daniel. Firstly, such an analysis indicates that the smaller episode is part of a larger clash of deities. Secondly, it shows that the editor /author utilises the episode to create a new cosmology. In this new cosmology, the Jewish deity is an almighty one, whilst other deities are seen as false and not real living gods. In his own way, the editor or author contributes to the way in which Jews regarded their God within the reality of the diaspora. Daniel Dragonslayer − Bel en die draak, Verse 23−27 (VAN/Die. In hierdie artikel word aspekte van narratiewe-kritiek, genre, redaksie-kritiek, die liggaam en ruimte op ’n unieke wyse gekombineer om ’n beliggaamde ruimteraamwerk te vorm. Hierdie beliggaamde ruimteraamwerk word gebruik om die tweede episode van ‘Bel en die Draak’, naamlik ‘Daniël, die Draakjagter’, te analiseer. Die artikel stel voor dat hierdie tweede episode van ‘Bel en die Draak’ in ’n resiproke verhouding met ‘Bel en die Draak’, sowel as met die boek Daniël gelees moet word. Indien die teks op hierdie voorgestelde wyse ontleed word, kom verskeie punte na vore. Eerstens word aangedui dat die kleiner episode deel van ’n groter gode-oorlog vorm. Tweedens, die skrywer/redakteur gebruik die kleiner episode as deel van ’n proses om ’n nuwe kosmologie te skep. Volgens hierdie nuwe kosmologie is die Joodse God ’n almagtige God, terwyl ander gode vals en nie ware lewende gode is nie. Op sy eie manier lewer die skrywer/redakteur ’n bydrae tot die

  16. Formation of the City of Belém (PA: Central Area and its Paper Historical and Geographical

    Directory of Open Access Journals (Sweden)

    Antônio Carlos Ribeiro Araújo Júnior

    2012-12-01

    Full Text Available In the 17th Century the urban life of Belém spread out from a promontorylocated at the meeting point of Guajará Bay and Guamá River. These "natural obstacles" (waterways, floodplains and flooded forest presented momentary setbacks to urban expansion. Overcoming these obstacles the city of Belém developed a central area characerized by change and continuity. By identifying and analyzing historical and geographical changes in the central area of Belém a better understanding can be obtained of new functions and features of urban space in Belém today.

  17. BELIEF dashboard - a web-based curation interface to support generation of BEL networks

    OpenAIRE

    Madan, Sumit; Hodapp, Sven; Fluck, Juliane

    2015-01-01

    The relevance of network-based approaches in systems biology to achieve a better understanding of biological mechanisms has increased enormously. The Biological Expression Language (BEL) is well designed to collate findings from scientific literature into biological network models. To facilitate encoding and biocuration of such findings in BEL, a free and user-friendly web-based curation interface called BELIEF Dashboard has been developed. The interface incorporates an information extraction...

  18. Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum β-Lactamase and Its Complexes with Moxalactam and Imipenem.

    Science.gov (United States)

    Pozzi, Cecilia; De Luca, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, Gian Maria; Mangani, Stefano; Docquier, Jean-Denis

    2016-12-01

    BEL-1 is an acquired class A extended-spectrum β-lactamase (ESBL) found in Pseudomonas aeruginosa clinical isolates from Belgium which is divergent from other ESBLs (maximum identity of 54% with GES-type enzymes). This enzyme is efficiently inhibited by clavulanate, imipenem, and moxalactam. Crystals of BEL-1 were obtained at pH 5.6, and the structure of native BEL-1 was determined from orthorhombic and monoclinic crystal forms at 1.60-Å and 1.48-Å resolution, respectively. By soaking native BEL-1 crystals, complexes with imipenem (monoclinic form, 1.79-Å resolution) and moxalactam (orthorhombic form, 1.85-Å resolution) were also obtained. In the acyl-enzyme complexes, imipenem and moxalactam differ by the position of the α-substituent and of the carbonyl oxygen (in or out of the oxyanion hole). More surprisingly, the Ω-loop, which includes the catalytically relevant residue Glu166, was found in different conformations in the various subunits, resulting in the Glu166 side chain being rotated out of the active site or even in displacement of its Cα atom up to approximately 10 Å. A BEL-1 variant showing the single Leu162Phe substitution (BEL-2) confers a higher level of resistance to CAZ, CTX, and FEP and shows significantly lower K m values than BEL-1, especially with oxyiminocephalosporins. BEL-1 Leu162 is located at the beginning of the Ω-loop and is surrounded by Phe72, Leu139, and Leu148 (contact distances, 3.5 to 3.9 Å). This small hydrophobic cavity could not reasonably accommodate the bulkier Phe162 found in BEL-2 without altering neighboring residues or the Ω-loop itself, thus likely causing an important alteration of the enzyme kinetic properties. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  19. Quasilocal energy and the Bel-Robinson tensor

    International Nuclear Information System (INIS)

    Krishnasamy, Ilangkovan

    1985-01-01

    The general-relativistic field equations are examined from the point of view of a local inertial observer and a quasilocal definitions of energy-momentum is thereby obtained. This definition relates to the Bel-Robinson tensor and the approach is shown to be consistent with the result obtained from the definition of energy given by Hawking. (author)

  20. Mööbel suvekodusse / Aili Ermel

    Index Scriptorium Estoniae

    Ermel, Aili

    2008-01-01

    2008. a. Milano messil "Salone Internazionale del Mobile" oli mööblit, mis projekteeritud ekstra õuele, aga oli ka sellist, mis sobib suvel õue ja talvel tuppa. Mööbel firmalt Cappellini, Gervason (disainer Paola Navone), Horm (disainer Mario Bellini), Zanotta (disainerid Gae Aulenti, Prospero Rasulo, Emaf Progetti, Roberto Barbieri), EMU (disainer Patricia Urquiola), Moroso (disainerid Nipa Doshi, Jonhatan Levien, Edward Van Vliet), Cassina (Tokujin Yoshioka) ja RODA. 14 värv. ill

  1. Unique characterization of the Bel-Robinson tensor

    International Nuclear Information System (INIS)

    Bergqvist, G; Lankinen, P

    2004-01-01

    We prove that a completely symmetric and trace-free rank-4 tensor is, up to sign, a Bel-Robinson-type tensor, i.e., the superenergy tensor of a tensor with the same algebraic symmetries as the Weyl tensor, if and only if it satisfies a certain quadratic identity. This may be seen as the first Rainich theory result for rank-4 tensors

  2. Residues R199H200 of prototype foamy virus transactivator Bel1 contribute to its binding with LTR and IP promoters but not its nuclear localization

    International Nuclear Information System (INIS)

    Ma, Qinglin; Tan, Juan; Cui, Xiaoxu; Luo, Di; Yu, Miao; Liang, Chen; Qiao, Wentao

    2014-01-01

    Prototype foamy virus encodes a transactivator called Bel1 that enhances viral gene transcription and is essential for PFV replication. Nuclear localization of Bel1 has been reported to rely on two proximal basic motifs R 199 H 200 and R 221 R 222 R 223 that likely function together as a bipartite nuclear localization signal. In this study, we report that mutating R 221 R 222 R 223 , but not R 199 H 200 , relocates Bel1 from the nucleus to the cytoplasm, suggesting an essential role for R 221 R 222 R 223 in the nuclear localization of Bel1. Although not affecting the nuclear localization of Bel1, mutating R 199 H 200 disables Bel1 from transactivating PFV promoters. Results of EMSA reveal that the R 199 H 200 residues are vital for the binding of Bel1 to viral promoter DNA. Moreover, mutating R 199 H 200 in Bel1 impairs PFV replication to a much greater extent than mutating R 221 R 222 R 223 . Collectively, our findings suggest that R 199 H 200 directly participate in Bel1 binding to viral promoter DNA and are indispensible for Bel1 transactivation activity. - Highlights: • The R 221 R 222 R 223 residues are essential for the nuclear localization of Bel1. • Although not affecting the nuclear localization of Bel1, mutating R 199 H 200 disables Bel1 from transactivating PFV promoters. • The R 199 H 200 residues directly participate in Bel1 binding to viral promoter DNA. • Mutating R 199 H 200 in Bel1 impairs PFV replication to a much greater extent than mutating R 221 R 222 R 223

  3. "Belõje slonõ" gotovõ k razdatshe / Viktor Matizen

    Index Scriptorium Estoniae

    Matizen, Viktor

    2006-01-01

    Venemaa filmikriitikute auhinna "Zolotoi Oven" asemel jagatakse sel aastal esmakordselt Ivan Maksimovi poolt modelleeritud "Valgeid Elevante" ("Belõi slon"). Vene filmikriitikute gildi president selle aasta nominentidest. Lisa : nimekiri "Nominandid preemiale "Valge Elevant" -2005"

  4. Demonstration of site-dependent dynamics of ozone effects in tobacco (Nicotina tabacum L. Bel W3) in Greater Rostock; Nachweis einer standoertlich differenzierten Dynamik der Ozonwirkung an Tabak (Nicotina tabacum L. Bel W3) im Grossraum Rostock

    Energy Technology Data Exchange (ETDEWEB)

    Odya, S.; Stuedemann, O.; Eckert, S. [Rostock Univ. (Germany). Inst. fuer Landschaftsplanung und Landschaftsoekologie

    1999-07-01

    The goal of the present study was to describe the genesis of a geographic pattern of phytotoxic ozone effects in the case of a mesoscale climate sequence. For this purpose the ''Applied Meteorology and Climatology'' working group carried out an active biomonitoring field trial with different bioindicator plants (Nicotina Tabacum L. Bel W3 and Bel B, bush bean, darnel, wheat and common nettle) over 4 vegetation periods. The trial was designed on the basis of existing knowledge on the spatially heterogeneous occurrence of ozone episodes and site-dependent phytotoxic ozone effects. [German] Das Ziel unserer Untersuchungen ist die Beschreibung der Genese des geographischen Musters phytotoxischer Ozonwirkungen im Bereich einer mesoskalen Klimasequenz in Nordost-Deutschland. Dazu wurde in Kenntnis des arealheterogenen Auftretens der Ozonepisoden und der standortabhaengigen phytotoxischen Ozonwirkung von der AG 'Angewandte Meteorologie und Klimatologie' ein aktives Biomonitoring mit verschiedenen Bioindikatorpflanzen (Nicotiana tabacum L. Bel W3 und Bel B, Buschbohne, Weidelgras, Weizen, Grosse Brennessel) ueber 4 Vegetationsperioden (1995-1998) im Freiland durchgefuehrt. (orig.)

  5. Neutralizing Antibodies to Enterovirus 71 in Belém, Brazil

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes C Gomes

    2002-01-01

    Full Text Available Non-polio enteroviruses (Coxsackievirus A, Coxsackievirus B, Echovirus and EV 68-72 which belong to the enterovirus (EV genus, Picornaviridae family, may be responsible for acute flaccid paralysis, aseptic meningitis, myocarditis, hepatitis, pleurodinia, neonatal sepsis, hand, foot and mouth disease (HFMD even though 50-80% of infections are asymptomatic. EV 71 has been responsible for outbreaks and epidemics of HFMD and acute neurologic disease justifying its study in our country. The aim of this study was to detect neutralizing antibodies (NtAb to EV 71 in individuals up to 15 years of age living in Belém, State of Pará, northern Brazil. Serum samples from 238 patients attending the Virology Sector of Evandro Chagas Institute in Belém, Brazil, were analyzed using microneutralization tests that included RD cells and BrCr strain. Overall 40.8% (97/238 of tested samples had NtAb to EV 71. Regarding the distribution per age group, 85.2% (92/108 of patients aged 0-3 years had no NtAb to this virus and 69.2% of those 12 to15 years of age were seropositive. These results confirm that EV 71 infection occurs in the city of Belém; and that a high rate of individuals in this study were infected aged 3 years and over and, when aged 15 years nearly 70% had EV 71 NtAb.

  6. Istemööbel Sheff = Sheff : modular seating furniture

    Index Scriptorium Estoniae

    2008-01-01

    Standardi istemööbel Sheff. Ühe laia käetoega tugitoole saab ühendada diivaniks, moodustada neist gruppe. Tugitoole täiendavad vaheplaadid, mis liidetuna tooli käetoega moodustavad lauakese. Disainer Katrin Soans, tema tähtsamad tööd. 2 värv. vaadet, foto K. Soansist

  7. Effects of alpha fetoprotein on escape of Bel 7402 cells from attack of lymphocytes

    International Nuclear Information System (INIS)

    Li, Mengsen; Liu, Xinhua; Zhou, Sheng; Li, Pingfeng; Li, Gang

    2005-01-01

    Involvement of AFP against apoptosis of tumor cell has been implicated in its evasion of immune surveillance. However, the molecular events of immune escape mechanisms are still unknown. The major observations reported here relate to a possible mechanism by which heptoloma Bel 7402 cells escape immune surveillance in vitro. Western blotting and a well-characterized cofocal scanning image were performed to analyze the expression of Fas/FasL and caspase-3 in co-cultured Bel 7402 and Jurkat cells. After co-culture with Jurkat cells, up-regulated Fas and reduced FasL expression could be observed. Treatment with AFP could remarkably inhibit the elevated Fas and, whereas, induce the FasL expression in co-cultured Bel 7402 cells. Cells co-culture could induce the expression of caspase-3 in both cells line. The elevated caspase-3 in Bel 7402 cells was abolished following the treatment of AFP. The expression of caspase-3 was elevated in co-cultured Jurkat cells treated with AFP. No detectable change on the expression of survivin was examined in both cells line. Monoclonal antibody against AFP treatment alone did not obviously influence the growth of cells, as well as the expression of Fas/FasL and caspase-3. However, the effect of AFP could be blocked by antibody. our results provide evidence that AFP could promote the escape of liver cancer cells from immune surveillance through blocking the caspase signal pathway of tumor cells and triggering the Fas/FasL interaction between tumor cells and lymphocytes

  8. Sexuelle Belästigung aus strafrechtlicher Sicht Sexual Harassment from the Perspective of Criminal Law

    Directory of Open Access Journals (Sweden)

    Maria Eder-Rieder

    2004-07-01

    Full Text Available Der Kern der Arbeit ist die juristische Aufarbeitung der Grenzen und Reichweite der in der Schweiz seit 1. Oktober 1992 in Kraft befindlichen Regelungen zur sexuellen Belästigung durch Vornahme einer sexuellen Handlung vor jemanden (Art. 198 Abs. 1 StGB, der tätlichen sexuellen Belästigung und der verbalen Belästigung (Art. 198 Abs. 2 StGB. Diese Tatbestände werden anhand von Beispielen erläutert, mit weiteren Varianten der sexuellen Belästigung verglichen und zu anderen Tatbeständen abgegrenzt. Ebenso wird auf das Verhältnis zum Zivilrecht und die Problematik des Strafprozesses eingegangen. Abschließend wird der kriminalpolitischen Frage über den Sinn der strafrechtlichen Sanktionierung nachgegangen.The core of this work is the judicial reappraisal of the boundaries and range of Swiss regulations—effective since October 1, 1992—on sexual harassment through carrying out a sexual action in the presence of someone (Art. 198 Paragraph 1 of the penal code or violent sexual harassment and verbal harassment (Art. 198 Paragraph 2 of the penal code. These elements of offences are illustrated on the basis of examples, are compared to further variations of sexual harassment and are distinguished from other offences. The relationship between civil law and the difficulties of criminal procedures are also dealt with. At the end of the book, the criminal-political question of the meaning of penal sanctions is examined.

  9. Nucleation on a stepped surface with an Ehrlich–Schwöbel barrier

    International Nuclear Information System (INIS)

    Chromcova, Z; Chvoj, Z; Tringides, M C

    2013-01-01

    During deposition on a stepped surface the growth mode depends on the conditions such as temperature T, deposition rate F and width of the terraces w. In this work we studied the influence of all the above mentioned characteristics using the kinetic Monte Carlo (kMC) technique. We concentrated on the conditions on the terrace at the moment of the first nucleation. The critical density of monomers for nucleation η m decreases with the width of the terrace and the nucleation starts at surprisingly low densities of monomers. We tested several definitions of the critical width for nucleation w c used in various articles in the past and we compared our results with results of the analytical steady-state mean-field model (Ranguelov and Altman 2007 Phys. Rev. B 75 245419). To check how the simplified assumption about the steady-state regime during deposition influences the resulting dependence of w c ≃ (D/F) κ , we set and also solved a time-dependent analytical model. This analytical model as well as kMC predict that w c ≃ (D/F) 1/5 . kMC simulation also shows that the Ehrlich–Schwöbel barrier has only limited influence on the nucleation on the stepped surface at conditions close to the nucleation regime. For all widths of terraces there is a critical value of the Ehrlich–Schwöbel barrier, and only below this critical value does the Ehrlich–Schwöbel barrier affect the final value of the density of nuclei. The results of the kMC are summarized in a semi-empirical analytical formula which describes the dependence of the step-flow growth and nucleation on the terrace width w, diffusion coefficient D and deposition rate F. In our simulations we tested two models of the stepped surface with different thicknesses of the step, both with an Ehrlich–Schwöbel barrier on the edge of the terrace. (paper)

  10. Photojournalism in the Belém Press: 1900–1950

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    Netília Silva dos Anjos Seixas

    2015-12-01

    Full Text Available This study looks at the course of photojournalism in the first half of the 20th century in the Belém press, in the State of Pará. This is exploratory research based on the iconographic and iconological analysis of images as understood by Panofsky and Kossoy. Bibliographical and documentary research together with an empirical analysis of data was conducted on three important newspapers in Pará: A Província do Pará, Folha do Norte and Estado do Pará, all available in the archives of the Arthur Vianna Public Library in Belém. Analyzing the data made it possible to provide a picture of the course of photojournalism in Pará for the major newspapers in circulation during the established time period, showing that even at the beginning of the century periodicals already recognized the power of images; something evident in publication. The data also showed that problems in the city, wars, politics, police and sports were the main issues for photojournalism in Pará throughout the decades studied in this paper.

  11. Oligocene age of the classic Belén fruit and seed assemblage of north coastal Peru based on diatom biostratigraphy

    Science.gov (United States)

    Manchester, Steven R.; Herrera, Fabiany; Fourtainer, Elisabeth; Barron, John A.; Martinez, Jean-Noël

    2012-01-01

    The Belén flora, in north coastal Peru, is the most diverse fruit and seed assemblage known from the Paleogene of South America. Almost no original paleobotanical work has been done on this assemblage since the pioneering treatments published by E.W. Berry, in the 1920’s and the precise age has not been settled. Nevertheless, the flora has been regarded as an important focal point in understanding the vegetational, orogenic and climatic history of northern South America, and in recent literature has been assumed to be early Eocene. In order to tighten the age assignment, which has varied from early Eocene to early Oligocene in the opinions of different authors, we revisited the Belén site, measured the stratigraphic section, and processed the fruit and seed-containing sediment for age-diagnostic microfossils. Although pollen and foraminifera were not recovered, the sediment is rich in diatoms. The diatom assemblage includes Lisitzinia ornata and Rocella vigilans among others, indicating a latest early Oligocene age (~30-28.5 Ma) for these deeper marine sediments that we infer to have been subsequently reworked into the Belén environment . This association leads us to consider the Belén flora, to be late Oligocene in age as is also consistent with its placement in the Mancora Formation. We also reevaluate the botanical identifications, based on the original museum specimens supplemented by more recently collected specimens. The Belén flora provides a window to extinct forests in South America before the rising of the Andes in western Peru.

  12. The museum as heritage, the republic as memory:art and colleting in Belém do Pará (1890-1940

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    Aldrin Moura de Figueiredo

    2014-12-01

    Full Text Available This article analyze the art collection of Museu de Arte de Belém as historical and cultural heritage of the city of Belém, State of Pará, Brazil. This collection also initiated in the Empire of Brazil, was strengthened during the early Republic as part of a political exercise that took the art and history as formative elements of nationality.

  13. Dining in the lions� den � Bel and the dragon, verses 28�42 (Old Greek/Theodotion

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    Joseph J. de Bruyn

    2015-03-01

    Full Text Available This article is part of a series of articles written on Bel and the dragon. This series of articles is an investigation into the Greek editor/author�s use of body, space, narrative and genre in creating a new reality regarding the Jewish deity. A spatial framework is used to specifically examine the third episode of Bel and the dragon, entitled Dining in the lions� den. It is suggested that the third episode of Bel and the dragon should be read in a reciprocal relationship with not only Bel and the dragon but also the larger book of Daniel. Firstly, such an analysis indicates that the smaller episode is part of a larger clash of deities. Secondly, it shows that the editor/ author utilises the episode to recreate a new cosmology. In this new cosmology, the God of Israel is an almighty deity whilst other deities are revealed as false and not real living gods. In his own way, the editor/author contributes to the way in which Jews regarded their God within the reality of the diaspora.Intradisciplinary and/or interdisciplinary implications: The aim with this article was to analyse Daniel 14 by means of new insights from developments in language studies. Until now, scholars tended to repeat each other in their analysis of Daniel 14. No attention was given to space, body or other aspects of new developments in the field of language. This article challenges the repetitive research previously done on Daniel 14.

  14. Effectiveness of Balancing Everyday Life (BEL) versus standard occupational therapy for activity engagement and functioning among people with mental illness - a cluster RCT study.

    Science.gov (United States)

    Eklund, Mona; Tjörnstrand, Carina; Sandlund, Mikael; Argentzell, Elisabeth

    2017-11-09

    Many with a mental illness have an impoverished everyday life with few meaningful activities and a sedentary lifestyle. The study aim was to evaluate the effectiveness of the 16-week Balancing Everyday Life (BEL) program, compared to care as usual (CAU), for people with mental illness in specialized and community-based psychiatric services. The main outcomes concerned different aspects of subjectively evaluated everyday activities, in terms of the engagement and satisfaction they bring, balance among activities, and activity level. Secondary outcomes pertained to various facets of well-being and functioning. It was hypothesized that those who received the BEL intervention would improve more than the comparison group regarding activity, well-being and functioning outcomes. BEL is a group and activity-based lifestyle intervention. CAU entailed active support, mainly standard occupational therapy. The BEL group included 133 participants and the CAU group 93. They completed self-report questionnaires targeting activity and well-being on three occasions - at baseline, after completed intervention (at 16 weeks) and at a six-month follow-up. A research assistant rated the participants' level of functioning and symptom severity on the same occasions. Non-parametric statistics were used since these instruments produced ordinal data. The BEL group improved more than the CAU group from baseline to 16 weeks on primary outcomes in terms of activity engagement (p life) more than the CAU group from baseline to the follow-up (p = 0.049). No differences were found at that time for activity balance, level of functioning and symptom severity. The BEL program was effective compared to CAU in terms of activity engagement. Their improvements were not, however, greater concerning other subjective perceptions, such as satisfaction with daily activities and self-rated health, and clustering effects lowered the dependability regarding findings of improvements on symptoms and

  15. Climatologia da estrutura vertical da atmosfera em novembro para Belém-PA Climatology of the atmospheric vertical structure over the Belém-PA city during november

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    Daniela dos Santos Ananias

    2010-06-01

    Full Text Available Usando um conjunto de dados para um período de 26 anos (1982 a 2007, este trabalho apresentou um estudo diagnóstico sobre a estrutura vertical da temperatura do ar, temperatura do ponto de orvalho e umidade relativa sobre a região de Belém-PA, durante o mês de novembro. As análises foram conduzidas para duas composições contrastantes no que se refere ao regime de precipitação: a composição dos anos chuvosos e a composição dos anos secos, as quais foram estabelecidas objetivamente pelo método dos percentis. Os resultados apresentados permitiram concluir que a principal diferença observada nos perfis de temperatura e umidade atmosférica, comparando-se os perfis dos anos chuvosos e secos, ocorre na camada atmosférica entre os médios e altos níveis da troposfera (entre os níveis padrões de 700 hPa e 400 hPa. Nesta camada, a diferença entre as temperaturas do ar e do ponto de orvalho é significativamente maior e o contraste de umidade associado à convecção também apresenta os maiores valores. Em geral, as composições demonstraram que os perfis de temperatura anomalamente mais quente (frio e os de umidade anomalamente mais úmido (seco associam-se aos anos com registro de chuva acima (abaixo do normal na região de Belém.The present work reports a diagnostic study on the vertical structure of air temperature, dew point temperature and relative humidity over the region of Belém-PA (eastern Amazon, based on monthly dataset for a period of 26 years (1982 to 2007. The focus is on the transition period from dry to wet season in the eastern Amazon, i.e., the month of November. Two contrasting composites in relation to the rainfall regime were considered: the wet and the dry year's composites, which were established objectively by the percentiles method. The results showed that the main difference observed in the temperature and humidity profiles, comparing dry and wet years, occurs in the atmospheric layer between the middle

  16. Suitability of Nicotiana tabacum 'Bel W3' for biomonitoring ozone in Sao Paulo, Brazil

    International Nuclear Information System (INIS)

    Sant'Anna, Silvia M.R.; Esposito, Marisia P.; Domingos, Marisa; Souza, Silvia R.

    2008-01-01

    Nicotiana tabacum 'Bel W3' is a widely used sensitive bioindicator for ambient ozone, but it is rarely used in tropical countries. Our goal was to determine the suitability of this plant for biomonitoring ozone in the city of Sao Paulo by evaluating the relationships between leaf necroses and ozone under field conditions and measurements of chlorophyll a fluorescence and antioxidants in plants exposed to different concentrations of ozone in closed chambers. While a weak linear relationship between leaf injury and ozone concentrations (R 2 = 0.10) was determined in the field, a strong linear relationship was observed in the chamber experiments. Maximum leaf injury was observed in plants submitted to 40 ppb, which coincided with a significant decrease in fluorescence and total ascorbic acid. The relationship between leaf damage observed in the field and ozone was improved when the concentrations were limited to 40 ppb (R 2 = 0.28). - Nicotiana tabacum 'Bel W3' is suitable for indicating low ozone levels in Brazil

  17. A Triterpenoid from Thalictrum fortunei Induces Apoptosis in BEL-7402 Cells Through the P53-Induced Apoptosis Pathway

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    Lvyi Chen

    2011-11-01

    Full Text Available Thalictrum fortunei S. Moore, a perennial plant distributed in the southeastern part of China, has been used in Traditional Chinese Medicine for thousands of years for its antitumor, antibacterial and immunoregulatory effects. In order to investigate the active components and the mechanism of the anti-tumor effects of Thalictrum fortunei, the growth inhibitory effects of eight triterpenoids isolated from the aerial parts of the plant on tumor cell lines were examined by 3-(4,5-dimethylthiazoy1-3,5-diphenyltetrazolium bromide (MTT assay. The MTT-assay results showed that the inhibitory activity of 3-O-β-D-glucopyranosyl-(1→4-β-D-fucopyranosyl(22S,24Z-cycloart-24-en-3β,22,26-triol 26-O-β-D-glucopyranoside (1 was stronger than that of the other seven tested triterpenoids on human hepatoma Bel-7402 cell line (Bel-7402, human colon lovo cells (LoVo, human non-small cells lung cancer NCIH-460 cells (NCIH-460 and human gastric carcinoma SGC-7901 cells (SGC-7901 after 48 h treatment in vitro, with the IC50 values of 66.4, 84.8, 73.5, 89.6 μM, respectively. Moreover, the antitumor mechanism of compound 1 on Bel-7402 cell was explored through nucleus dyeing, fluorescence assay, flow cytometry and western blot. The flow cytometric analysis results revealed that compound 1 caused apoptosis and mitochondrial membrane potential (MMP loss in Bel-7402 cells. A fluorescence assay indicated that intracellular reactive oxygen species (ROS were markedly provoked by compound 1 treatment compared to control cells. Immunoblot results showed that compound 1 significantly increased the expression levels of cleaved caspase-3, P53 and Bax protein, and decreased the expression level of Bcl-2 protein. These findings indicate that compound 1 inhibits the growth activity of tumor cells, probably through the P53 protein-induced apoptosis pathway.

  18. [Knockdown of DNA-PKcs inhibits cell cycle and its mechanism of drug-resistant Bel7402/5-Fu hepatocellular carcinoma cells].

    Science.gov (United States)

    Li, Dayu; Liu, Yun; Yu, Chunbo; Liu, Xiping; Fan, Fang

    2017-12-01

    Objective To study the effect of the knock-down of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) on the cell cycle of the multidrug-resistant (MDR) Bel7402/5-Fu hepatocellular carcinoma cells and its MDR mechanism. Methods After cationic liposome-mediated siDNA-PKcs oligonucleotide transfection, the drug sensitivity of Bel7402/5-Fu cells to 5-fluorouracil (5-Fu) and adriamycin (ADM) was determined by MTT assay; the cell cycle were detected by flow cytometry; meanwhile, the protein expressions of cell cycle-related proteins P21, cell cycle protein B1 (cyclin B1), cell cycle division protein 2 (CDC2) were tested by Western blotting; the expressions of ataxia telangiectasia mutated (ATM) and p53 at both mRNA and protein levels were detected by real-time PCR and Western blot analysis. Results The MTT results showed siDNA-PKcs increased the chemotherapeutic sensitivity of Bel7402/5-Fu cells to 5-Fu and ADM. The flow cytometric analysis showed siDNA-PKcs decreased the percentage of S-phase cells but increased the percentage of G2/M phase cells. Western blotting showed siDNA-PKcs increased the protein expression of P21 but decreased cyclinB1 and CDC2 proteins. In addition, siDNA-PKcs also increased the expressions of ATM and p53. Conclusion DNA-PKcs silencing increases P21 while decreases cyclin B1 and CDC2 expressions, and finally induces G2/M phase arrest in Bel7402/5-Fu cells, which may be related to ATM-p53 signaling pathway.

  19. Vabariigi Valitsuse istungitesaali mööbel = Furniture for the Estonian Government cabinet's meeting room

    Index Scriptorium Estoniae

    2008-01-01

    Stenbocki Maja istungitesaali (Rahukohtu 3, Tallinn) mööbel. Disainerid: Katrin Vaikla, Argo Vaikla (Vaikla Disain), Liis Tarbe (Torpedo Interior OÜ). Argo ja Katrin Vaiklast, Vaikla Disaini tähtsamad tööd. Liis Tarbest, koostöös Vaikla Disainiga valminud tööd. 6 värv. vaadet, fotod sisearhitektidest

  20. Paracoccidioidomicose em crianças em Belém do Pará

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    Fonseca Eliane R.S.

    1999-01-01

    Full Text Available No período janeiro de 1985 e julho de 1996 foram observados 102 casos de paracoccidioidomicose em hospital de Belém, PA. Treze pacientes eram crianças entre 3 e 13 anos de idade, com predomínio do sexo feminino (8:5. Todos apresentavam a forma disseminada subaguda da micose. É comentada a alta prevalência da micose em crianças em áreas endêmicas da Região Amazônica.

  1. Autoregulatory Feedback Mechanism of P38MAPK/Caspase-8 in Photodynamic Therapy-Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy Phthalocyanine Zinc-Induced Apoptosis of Human Hepatocellular Carcinoma Bel-7402 Cells

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    Yu Wang

    2014-01-01

    Full Text Available Photodynamic therapy (PDT is a novel and promising antitumor treatment. Our previous study showed that hydrophilic/lipophilic tetra-α-(4-carboxyphenoxy phthalocyanine zinc- (TαPcZn- mediated PDT (TαPcZn-PDT inhibits the proliferation of human hepatocellular carcinoma Bel-7402 cells by triggering apoptosis and arresting cell cycle. However, mechanisms of TαPcZn-PDT-induced apoptosis of Bel-7402 cells have not been fully clarified. In the present study, therefore, effect of TαPcZn-PDT on apoptosis, P38MAPK, p-P38MAPK, Caspase-8, Caspase-3, Bcl-2, Bid, Cytochrome c, and mitochondria membrane potential in Bel-7402 cells without or with P38MAPK inhibitor SB203580 or Caspase-8 inhibitor Ac-IEFD-CHO was investigated by haematoxylin and eosin (HE staining assay, flow cytometry analysis of annexin V-FITC/propidium iodide (PI double staining cells and 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide (JC-1, and immunoblot assay. We found that TαPcZn-PDT resulted in apoptosis induction, activation of P38MAPK, Caspase-8, Caspase-3, and Bid, downregulation of Bcl-2, release of Cytochrome c from mitochondria, and disruption of mitochondrial membrane potential in TαPcZn-PDT-treated Bel-7402 cells. In contrast, SB203580 or Ac-IEFD-CHO attenuated induction of apoptosis, activation of P38MAPK, Caspase-8, Caspase-3, and Bid, downregulation of Bcl-2, release of Cytochrome c from mitochondria, and disruption of mitochondrial membrane potential in TαPcZn-PDT-treated Bel-7402 cells. Taken together, we conclude that Caspase-3, Bcl-2, Bid, and mitochondria are involved in autoregulatory feedback of P38MAPK/Caspase-8 during TαPcZn-PDT-induced apoptosis of Bel-7402 cells.

  2. Atypical rotavirus among diarrhoeic children living in Belém, Brazil Rotavírus atípicos detectados em crianças diarréicas, em Belém, Brasil

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    Yvone B. Gabbay

    1989-03-01

    Full Text Available Atypical rotaviruses were detected in faeces from two diarrhoeic children living in Belém, Pará, Brazil. Rotavirus particles were detected by electron microscopy and the RNA electrophoresis showed patterns which were compatible with group C rotaviruses. Tests for the presence of group A antigen by enzyme-linked-immunosorbent assay (ELISA were negative. The two children had three successive rotavirus infection and in both cases the atypical strains were excreted at the time of the third infection, causing a mild and short-lasting disease.Rotavírus atípicos foram detectados nas fezes de duas crianças diarreícas residentes em Belém, Brasil. Partículas de rotavírus foram visualizadas por microscopia eletrônica nos espécimes fecais de ambos os pacientes, tendo a eletroforese do ácido ribonucleico (ARN exibido padrões compatíveis com rotavírus do grupo C. Testes imunoenzimáticos (ELISA foram negativos quanto à presença de antígenos do grupo A. As duas crianças apresentaram três infecções sucessivas por esse agente, sendo que, em ambos os casos, os rotavírus atípicos foram excretados por ocasião da terceira infecção, produzindo sintomas brandos e de pouca duração.

  3. The efficiency of tobacco Bel-W3 and native species for ozone biomonitoring in subtropical climate, as revealed by histo-cytochemical techniques

    International Nuclear Information System (INIS)

    Alves, Edenise S.; Moura, Barbara B.; Pedroso, Andrea N.V.; Tresmondi, Fernanda; Domingos, Marisa

    2011-01-01

    We aimed to verify whether hydrogen peroxide (H 2 O 2 ) accumulation and cell death are detected early in three bioindicators of ozone (O 3 ), Nicotiana tabacum 'Bel-W3', Ipomoea nil 'Scarlet O'Hara' and Psidium guajava 'Paluma', and whether environmental factors also affect those microscopic markers. The three species were exposed to chronic levels of O 3 in a subtropical area and a histo-cytochemical technique that combines 3,3'-diaminobenzidine (DAB) with Evans blue staining was used in the assessments. The three species accumulated H 2 O 2 , but a positive correlation with O 3 concentration was only observed in N. tabacum. A positive correlation between O 3 and cellular death was also observed in N. tabacum. In I. nil and P. guajava, environmental factors were responsible for symptoms at the microscopic level, especially in P. guajava. We conclude that the most appropriate and least appropriate bioindicator plant for O 3 monitoring in the subtropics are N. tabacum 'Bel-W3' and P. guajava 'Paluma', respectively. - Highlights: → H 2 O 2 and cell death occur in response to O 3 and other stressful factors. → H 2 O 2 can be detected by DAB and cell death by Evans blue staining. → These techniques contribute for analysis of susceptible bioindicator species. → H 2 O 2 and cell death were explained by high levels of O 3 in N. tabacum 'Bel-W3'. → N. tabacum is the most appropriate plant for monitoring in subtropics. - Nicotiana tabacum 'Bel-W3' is better than native species for O 3 biomonitoring in the subtropics, as revealed by histo-cytochemical techniques.

  4. A logística como ferramenta eficaz no transporte urbano de passageiros: o caso da empresa de transporte metropolitano Belém Rio

    OpenAIRE

    Espirito Santo, Rodivaldo Brito do

    2010-01-01

    Este estudo trata a questão da Logística na operacionalização do transporte público por ônibus da Região Metropolitana de Belém - RMB, particularmente, da concessionária Empresa Belém Rio, que atua na Capital do Pará. O foco principal foi perceber se existem indicadores de desempenho eficaz na operacionalização mais racional e equilibrada desse modal de transporte. A pesquisa foi conduzida por uma revisão bibliográfica de estudos da Logística e suas operações, como também da...

  5. Suitability of Nicotiana tabacum 'Bel W3' for biomonitoring ozone in Sao Paulo, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Sant' Anna, Silvia M.R.; Esposito, Marisia P.; Domingos, Marisa [Instituto de Botanica, Secao de Ecologia, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Souza, Silvia R. [Instituto de Botanica, Secao de Ecologia, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil)], E-mail: souzasrd@terra.com.br

    2008-01-15

    Nicotiana tabacum 'Bel W3' is a widely used sensitive bioindicator for ambient ozone, but it is rarely used in tropical countries. Our goal was to determine the suitability of this plant for biomonitoring ozone in the city of Sao Paulo by evaluating the relationships between leaf necroses and ozone under field conditions and measurements of chlorophyll a fluorescence and antioxidants in plants exposed to different concentrations of ozone in closed chambers. While a weak linear relationship between leaf injury and ozone concentrations (R{sup 2} = 0.10) was determined in the field, a strong linear relationship was observed in the chamber experiments. Maximum leaf injury was observed in plants submitted to 40 ppb, which coincided with a significant decrease in fluorescence and total ascorbic acid. The relationship between leaf damage observed in the field and ozone was improved when the concentrations were limited to 40 ppb (R{sup 2} = 0.28). - Nicotiana tabacum 'Bel W3' is suitable for indicating low ozone levels in Brazil.

  6. The efficiency of tobacco Bel-W3 and native species for ozone biomonitoring in subtropical climate, as revealed by histo-cytochemical techniques

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Edenise S., E-mail: ealves@ibot.sp.gov.br [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Moura, Barbara B., E-mail: bmourabio@gmail.com [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Pedroso, Andrea N.V., E-mail: andreanvpedroso@gmail.com [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Tresmondi, Fernanda, E-mail: ftresmondi@gmail.com [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Domingos, Marisa, E-mail: mmingos@superig.com.br [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil)

    2011-12-15

    We aimed to verify whether hydrogen peroxide (H{sub 2}O{sub 2}) accumulation and cell death are detected early in three bioindicators of ozone (O{sub 3}), Nicotiana tabacum 'Bel-W3', Ipomoea nil 'Scarlet O'Hara' and Psidium guajava 'Paluma', and whether environmental factors also affect those microscopic markers. The three species were exposed to chronic levels of O{sub 3} in a subtropical area and a histo-cytochemical technique that combines 3,3'-diaminobenzidine (DAB) with Evans blue staining was used in the assessments. The three species accumulated H{sub 2}O{sub 2}, but a positive correlation with O{sub 3} concentration was only observed in N. tabacum. A positive correlation between O{sub 3} and cellular death was also observed in N. tabacum. In I. nil and P. guajava, environmental factors were responsible for symptoms at the microscopic level, especially in P. guajava. We conclude that the most appropriate and least appropriate bioindicator plant for O{sub 3} monitoring in the subtropics are N. tabacum 'Bel-W3' and P. guajava 'Paluma', respectively. - Highlights: > H{sub 2}O{sub 2} and cell death occur in response to O{sub 3} and other stressful factors. > H{sub 2}O{sub 2} can be detected by DAB and cell death by Evans blue staining. > These techniques contribute for analysis of susceptible bioindicator species. > H{sub 2}O{sub 2} and cell death were explained by high levels of O{sub 3} in N. tabacum 'Bel-W3'. > N. tabacum is the most appropriate plant for monitoring in subtropics. - Nicotiana tabacum 'Bel-W3' is better than native species for O{sub 3} biomonitoring in the subtropics, as revealed by histo-cytochemical techniques.

  7. Qualidade da dieta de gestantes em uma unidade básica de saúde em Belém do Pará: um estudo piloto = Diet quality of pregnant women in a basic health unit in Belém, Pará: a pilot study

    Directory of Open Access Journals (Sweden)

    Gomes, Késia Carolinne Ferreira

    2015-01-01

    Full Text Available Objetivo: Avaliar a qualidade da dieta de gestantes cadastradas em uma unidade básica de saúde em Belém do Pará. Materiais e Métodos: Estudo piloto de delineamento transversal, realizado com gestantes em uma unidade básica de saúde em Belém do Pará no ano de 2011. Foram aplicados questionário estruturado e inquérito alimentar recordatório de 24 horas em duplicata. O peso e a altura foram aferidos durante a entrevista para análise do Índice de Massa corporal (IMC. Para a avaliação da qualidade da dieta, foram analisados 10 de seus componentes de acordo com o índice da alimentação saudável (IAS. Resultados: Foram avaliadas 25 gestantes, com média de idade de 24,2±7,2 anos, peso 58,6±6,9 kg e IMC 25,7±3,9. Notou-se que 32% (8 apresentam excesso de peso. Pelo IAS, observou-se que 100% (25 das gestantes avaliadas não possuem uma dieta adequada, sendo que 60% (15 possuem uma dieta que necessita de modificações e 40% (10 apresentam uma dieta inadequada. Conclusão: A qualidade da alimentação de gestantes cadastradas em uma unidade básica de saúde em Belém do Pará se mostrou aquém das recomendações preconizadas, demostrando que 100% das gestantes possuem uma dieta inadequada

  8. [Santa Casa de Misericórdia and hygienist policies in Belém do Pará in the late nineteenth century].

    Science.gov (United States)

    Miranda, Cybelle Salvador; Beltrão, Jane Felipe; Henrique, Márcio Couto; Bessa, Brena Tavares

    2015-01-01

    The article analyzes the relationship between hygienist policies in effect in Belém in the late nineteenth century and the expansion of activities of the Santa Casa de Misericórdia do Pará. Considered one of the first hospital institutions in the former Grão-Pará Province, in addition to its own hospital, the Brotherhood administered several other health facilities in the capital, and the study of its physical displacement made it possible to "map" three health centers in Belém: Pioneer, Expansion and the Santa Casa, which reinforce the growth vectors of the city. The expansion of its activities is configured as the expansion of the Santa Casa de Misericórdia to serve the underprivileged and sick, preceding the establishment of a public health system in Pará.

  9. Ozone biomonitoring in Pakistan using tobacco cultivar Bel-W3

    International Nuclear Information System (INIS)

    Kafiatullah, A.; Shamsi, S.R.A.

    2012-01-01

    The present study depicts a comparison of ozone (O/sub 3/) concentrations over a decade time (1993-94 to 2006) using plant biomonitoring and continuous ozone monitors techniques in Lahore city of Pakistan. The variations in O/sub 3/ levels were assessed at city centre, suburbs and semi-rural/rural locations in and around the city of Lahore by using American O/sub 3/-sensitive tobacco biomonitor plant ( Nicotiana tabaccum L. cv. Bel-W3) for the first time in Pakistan during 1993 and 1994 seasons through weekly assessment of visible damage to leaves. Results for both 1993 and 1994 seasons indicated significant differences between sites in the mean 6-h O/sub 3/ concentrations with a range of over 20 ppb and 15 ppb across the sites in 1993 and 1994, respectively. An inverse relationship between the levels of NO/sub 2/ and O/sub 3/ was found during investigation. The highest O/sub 3/ levels of 75-80 ppb were found at rural areas and the lowest at city centre sites. The extent of O/sub 3/ injury on the tobacco cv. Bel-W3 leaves reflected the trends seen in O/sub 3/ concentrations. The highest and lowest leaf injury indices of 18-27% and 5-7% occurred at the rural and city centre sites, respectively. Results for 2006 season indicated the highest seasonal mean O/sub 3/ concentration of 100 ppb in semi-rural areas compared with city centre sites (68 ppb). The highest 26% and 20% increase in O/sub 3/ levels was observed at rural/semi-rural and city centre sites, respectively when compared with 1993 O/sub 3/ survey. Application of O/sub 3/ biomonitoring technique proved very cost-effective and feasible for the estimation of atmospheric O/sub 3/ levels in South East Asian regions like Pakistan where shortage of electric supply, trained man power and poverty is already playing havoc. (author)

  10. En analyse av prestasjonsbasert belønning og hvilken effekt den har i Flytoget

    OpenAIRE

    Stousland, Kine

    2013-01-01

    Prestasjonsbasert belønning har vært i vinden de siste årene, og stadig flere bedrifter har tatt i bruk denne lønnsmetoden for å motivere ansatte til høyere effektivitet og bedre prestasjoner. Flytoget har kastet seg på denne bølgen og laget en medarbeiderbonus med samme kriterier for hele bedriften. Bonusen blir utbetalt en gang per år, og for å få full bonus må Flytoget oppnå 97% kundetilfredshet og fastsatt budsjett. Flytoget er en relativt liten bedrift med 334 ansatte. Hovedoppgaven t...

  11. Çamlıbel - Ulubey (Uşak) Beyaz Mermerinin Jeolojik ve Fiziko-Mekanik Özelliklerinin Araştırılması

    OpenAIRE

    ÇELİK, Mustafa Yavuz; KIRILIVEREN, Sabri

    2012-01-01

    Menderes Masifinde yer alan Uşak bölgesi önemli bir mermer potansiyeline sahiptir. Bölgede Karahallı, Sivaslı ve Ulubey ilçeleri civarında mermer blok üretimi yapılmaktadır. Bu makalede, Çamlıbel-Ulubey (Uşak) beyaz mermerinin, mermer olarak kullanılabilirliği irdelenmiş ve yöre mermerleriyle karşılaştırılmaları yapılmıştır. Çamlıbel-Ulubey (Uşak) beyaz mermerinin özelliklerini belirlemek amacıyla yapılan deneylerde özgül kütle 2,73 g/cm3, kütlece su emme oranı % 0,06, doluluk oranı % 99,3, b...

  12. Preliminary study of MR diffusion weighted imaging in nude mice models of hepatic Bel7402 tumors after adenovirus-mediated cytosine diaminase-thymidine kinase gene therapy

    International Nuclear Information System (INIS)

    Jiang Xinqing; Chen Liang; Wu Hongzhen; Huang Jingjun; Wei Xinhua; Mo Lei; Yang Ruimeng; Xiao Xiangsheng

    2012-01-01

    Objective: To study the characteristics of DWI in nude mice models of hepatic Bel7402 tumors after treatment with adenovirus-mediated cytosine diaminase-thymidine kinase (Ad. CD-TK) double suicide gene therapy, and then to identify whether DWI can be used for assessing curative effect of postoperative tumors. Methods: Thirty nude mice models of hepatic Bel7402 tumors were successfully created using cell suspension method, after the tumor grew to more than 1 cm in diameter, 20 tumor models were treated by intratumoral administration of Ad. CD-TK for 3 days plus intraperitonea (i.p.) treatment with 5-Fc and GCV for the duration of the study.Then they were randomly divided into three groups during 5-Fc and GCV treatment. The remaining 10 tumor models were used as controls. MR scanning were performed in 10 th day before and after tumor implantation in all models by using EPI-SE series and SENSE technology for treatment group. Tumor volumes and ADC values were calculated pretreatment and posttreatment. Cell apoptosis were determined by using TUNEL method. Analyze the change of ADC and apoptosis index (AI) in different times, t test was used for comparison the difference of AI and ADC values respectively. Results: After 10 days,the tumor volumes of the treatment groups and controls were respectively (724.16 ±57.45) mm 3 , (754.57 ± 66.84) mm 3 , with no significant difference (t=0.488, P >0.05). The ADC values of the treatment groups were (0.98 ±0.11) × 10 -3 mm 2 /s,the ones of the control groups were (0.68 ±0.04) × 10 -3 mm 2 /s; AI of the treatment groups were (23.25 ±6.57)%, the ones of the control groups were (2.57 ± 0.58)%. There were difference in both groups (t=4.473, 5.874; P<0.01). Conclusion: DWI can be effectively to monitor the early pathological changes of hepatic Bel7402 tumors after Ad. CD-TK double suicide gene therapy, and provide experimental evidences for clinical application. (authors)

  13. Os sefarditas de Belém do Pará: história e língua

    Directory of Open Access Journals (Sweden)

    Cássia Scheinbein

    2009-12-01

    Full Text Available Resumo: A contextualização sócio-histórica do hakitia, língua românica e judaica, em avançado processo de extinção, na comunidade sefardita de Belém do Pará, Brasil, é apresentada neste artigo. Descreve-se sua formação a partir do século XV, como consequência da diáspora dos judeus da Hispânia Medieval, até os dias atuais no Brasil. Especial relevância é dada à sua inserção cultural ao longo desse período de tempo. Uma lista de provérbios e frases, com base em dados linguísticos atuais coletados na cidade, está presente no final deste artigo. Palavras-chave: Contato linguístico; judeu-espanhol; sefardita; hakitia; provérbios. Resumen: La contextualización socio-histórica del hakitia, lengua románica y judaica, en avanzado proceso de extinción, en la comunidad sefardita de Belém do Pará, Brasil, es presentada en este artículo. Se describe su formación desde el siglo XV, como consecuencia de la diáspora de los judíos de la Hispania Medieval, hasta hoy en Brasil.  Especial relevancia es dada a su inserción cultural al largo de ese período de tiempo. Una lista de refranes y frases, con base en datos linguísticos actuales coletados en la dicha ciudad, está presente al final de este artículo.Palabras-clave: Contacto linguístico; judeoespañol; sefardita; hakitia; refranes.Abstract: The sociohistorical contextualization of hakitia, a jewish and romance language, in advanced process of extinction in the Sephardic community of Belém in the state of Pará, Brazil, is presented in this article. Its formation is described from the XV century, as consequence of the diaspora of the jews of Medieval Hispania, until the present day in Brazil. Special relevance is given to their cultural insertion along that period of time. A list of proverbs and phrases, on the basis of current linguistic data collected in the city, is presented in the end of this article. Keywords: Linguistic contact; judeo-spanish; sephardi

  14. Breakdown voltage mapping through voltage dependent ReBEL intensity imaging of multi-crystalline Si solar cells

    Science.gov (United States)

    Dix-Peek, RM.; van Dyk, EE.; Vorster, FJ.; Pretorius, CJ.

    2018-04-01

    Device material quality affects both the efficiency and the longevity of photovoltaic (PV) cells. Therefore, identifying these defects can be beneficial in the development of more efficient and longer lasting PV cells. In this study, a combination of spatially-resolved, electroluminescence (EL), and light beam induced current (LBIC) measurements, were used to identify specific defects and features of a multi-crystalline Si PV cells. In this study, a novel approach is used to map the breakdown voltage of a PV cell through voltage dependent Reverse Bias EL (ReBEL) intensity imaging.

  15. Belém’s built form and its developments to the formation of a system of open spaces accessible to population

    Directory of Open Access Journals (Sweden)

    Ana Claudia Duarte Cardoso

    2016-07-01

    Full Text Available This paper presents a characterization of the built space of Belém highlighting, its estuarine condition, physical geography and its economic, social and spacial development. It is based on Quapá-SEL Workshop conclusions held in Belém, in May 2015, in which teachers and students from São Paulo and Pará Federal Universities assessed the conditions of urban open spaces of the city. The results highlight a disarticulation between real estate agents strategies and of urban management towards structuring an Open Spaces System (SEL in Portuguese, as well as its limited appropriation by the population. There is a remarkable differentiation between the landscapes of central area in opposition / contraposition to that at the city’s expansion area. This debate showed how much permanent preservation areas on the banks of inland rivers and islands (the main green spaces of the city and main linkage with the Amazonian biome, with its landscape potentials, have been unevenly appropriated in the city, through gentrification.

  16. Perfil dos idosos internados no Hospital Geral em Belém (Pará Perfil de los ancianos internados en el Hospital General en Belém (Pará Brasil Profile of the elderly admited in a General Hospital at Belém (Pará - Brazil

    Directory of Open Access Journals (Sweden)

    Maria Izabel Penha de Oliveira Santos

    2007-03-01

    Full Text Available O estudo objetivou identificar o perfil dos idosos internados em um hospital geral da rede pública de saúde em Belém (Pará. Estudo transversal, retrospectivo, analítico. Foram analisadas variáveis sociodemográficas, causas da internação, tempo de permanência, complicações e dependência para cuidados de enfermagem, em 160 prontuários, em 2001. A análise estatística foi processada pelo programa eletrônico Epi-info 6.04. Os resultados apontam: A idade variou entre 65 e 74 anos (43,1%, e os idosos eram do sexo masculino (53,1%. A maior freqüência das internações foi por doenças respiratórias (53,7%; os sintomas evidentes foram dispnéia, hipertemia e hipertensão; e o tempo médio de permanência foi de 16 dias. O tempo de internação prolongado aparece como um fator de risco no desenvolvimento de incapacidades, pela imobilidade no leito, complicações como úlceras de decúbito e demais iatrogenias. Houve dependência para os cuidados de enfermagem e necessidade de intervenção interdisciplinar.El estudio tiene como objetivo identificar el perfil de ancianos hospitalizados en hospital general de salud pública, en Belém, Estado Pará. Estudio cuantitativo, retrospectivo y analitico. Analizadas variables sócio-demográficas, causas de internación, tiempo de permanencia, complicaciónes y dependencias de la enfermería en muestra de 160 historias en 2001. Analisys estadística fué a través del programa electrónico Epi-info 6.04. Los resultados apuntaran: La edad varió de 64 a 74 años (43, y 85 (53,1% y los ancianos eran del sexo masculino, la major frecuencia de la internaciónes fueron enfermedades respiratorias (53,7%, los síntomas evidentes disnea, hipertermia na hipertensión, tiempo promedio de 16 dias. Los ancianos se internaron en media dos veces al año , tiempo de internación largo aparece como factor de riesgo en el desarrollo de incapacidad, por la inmobilidad en las camas, complicaciónes como úlceras

  17. O bairro Batista Campos e as dinâmicas do tempo na cidade de Belém, Brasil: memórias e paisagens arruinadas

    Directory of Open Access Journals (Sweden)

    Flávio Leonel Abreu da Silveira

    Full Text Available O artigo propõe uma reflexão acerca das memórias de moradores do bairro Batista Campos, situado na cidade de Belém, Pará, de maneira a possibilitar, a partir de suas narrativas, a compreensão dos processos de transformação das paisagens urbanas com as quais possuem vínculos simbólico-afetivos. Em nossa análise, consideramos a emergência do fenômeno das ruínas e a dinâmica de práticas sociais que cercam os moradores do bairro. A pesquisa parte das relações dos interlocutores com as edificações antigas, que hoje constituem paisagens arruinadas, para compreender como estes sujeitos se conectam, por meio do ato criativo de rememorar, a uma Belém de outrora, a outras pessoas e a práticas sociais diversas.

  18. Orphanato Municipal de Belém: acolhimento, educação e instrução a meninas (1893-1911 - Orphanato Municipal de Belém: greeting, education and instruction to girls (1893-1911

    Directory of Open Access Journals (Sweden)

    Antonio Valdir Monteiro Duarte, Brasil

    2014-05-01

    Full Text Available Este artigo analisa as práticas educativas aplicadas a centenas de meninas que viveram em condição asilar durante a administração de Antonio José de Lemos (1897-1911, período marcado por transformações políticas, econômicas e sociais na capital paraense. Com o objetivo entender as práticas educativas no internato, o estudo revelou que, mesmo se tratando de uma instituição de natureza filantrópica, pelo menos no seu início, os regulamentos, programas e compêndios eram semelhantes aos estabelecidos para as demais escolas públicas. Ficou evidenciado que as disciplinas que envolviam as habilidades práticas, como trabalhos manuais, trabalhos de agulha e as prendas domésticas, tinham prioridade e ocupavam grande parte do tempo das educandas órfãs.Palavras-chave: meninas órfãs, práticas educativas, Orphanato Municipal de Belém.ORPHANATO MUNICIPAL DE BELÉM: GREETING, EDUCATION AND INSTRUCTION TO GIRLS (1893-1911AbstractThis article examines the educational practices applied to hundreds of girls who lived in asylum status during the administration of Antonio José de Lemos (1897-1911, in a period marked by major political, economic and social transformations in the capital of Pará. In order to understand, the educational practices at boarding school, the study revealed that, even with a philanthropic nature, at least in its beginning, regulations, programs and textbooks were similar to those established for other public schools. However, it became evident that the subjects involving practical skills like arts and crafts, needlework and household gifts, had priority and occupied much of the time of grassroots orphans. Key-words: orphan girls, educational practices, Orphanato Municipal de Belém.ORPHANATO MUNICIPAL DE BELÉM: SALUDO, EDUCACIÓN E INSTRUCCIÓN A LAS CHICAS (1893-1911ResumenEste artículo examina las prácticas educativas aplicadas a cientos de chicas que vivió en estado de asilo durante la administración de

  19. Impact of Dietary, Socioeconomic, and Physical Factors on Obese and Overweight Schoolchildren Living in Sidi-Bel-Abbes (West of Algeria and Ain Defla (Centre

    Directory of Open Access Journals (Sweden)

    Didaoui Hayat

    2018-03-01

    Full Text Available Background and aims: The aim of the current study was to assess the impact of environmental factors; food, socio-economic, and physical activity, on a group of obese children living in Ain-Defla (Center Algeria and Sidi-Bel-Abbes (West Algeria.

  20. Anti-Toxoplasma gondii antibodies in beef cattle slaughtered in the metropolitan region of Belém, Brazilian Amazon

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    Ediclei Lima do Carmo

    Full Text Available Abstract The relevance of consuming raw or undercooked beef in the transmission of toxoplasmosis is unclear due to the high resistance of cattle to infection. However, this possibility needs to be considered in endemic areas, such as the Amazon, where the consumption of beef is frequent. The objective of this study was to determine the frequency of anti-Toxoplasma gondii IgG antibodies in beef cattle slaughtered in the metropolitan region of Belem, Pará state, Brazil. Blood samples were collected from 500 animals of both genders in a licensed slaughterhouse in Belém. Anti-T. gondii IgG antibodies were detected by an indirect immunofluorescence assay (IFA with a cut-off titer of 1:64. Anti-T. gondii antibodies were found in 203 animals (40.6%, with a titer of 64 in 112 animals (55.2%, 128 in 68 animals (33.5%, 256 in 15 animals (7.4%, 512 in 5 animals (2.5%, and 1,024 in 3 animals (1.4%. No significant difference was observed between males and females (p > 0.05. The high frequency of anti-T. gondii antibodies observed in beef cattle slaughtered in Belém indicates that the meat of these animals may be an important source of infection for humans and carnivorous domestic animals when inadequately cooked beef is consumed.

  1. Arbetsmöbel för ungdomar : Beskrivning av designprocessen i ett samarbete med IKEA

    OpenAIRE

    Leckström, Anna

    2007-01-01

    Rapporten beskriver ett designprojekt, utfört som en del av examensarbetet på 15 HP, jag utfört som avgångsstudent på möbeldesignprogrammet vid Carl Malmsten Centrum för Träteknik & Design. Från Ronnie Runesson, produktutvecklare på IKEA of Sweden, fick jag ett uppdrag, ett reellt projekt att arbeta med. Projektet handlade om att ta fram ett koncept på en ny typ av arbetsmöbel för ungdomar i åldersgruppen 12 – 18 år. Målet med projektet var att, förutom att leverera ett fungerande koncept...

  2. Caridade e saúde pública em tempo de epidemias. Belém 1850-1890

    OpenAIRE

    COSTA, Magda Nazaré Pereira da

    2006-01-01

    Obrigados a enfrentar uma grave crise epidêmica desencadeada ao longo de quase toda a segunda metade do século XIX, os habitantes de Belém assistem, a partir daquele momento, a uma intensa mobilização social em prol da preservação da saúde pública, que há muito deixara de ser objeto de interesse do Governo Provincial e que agora se via ameaçada pela fúria da febre amarela, da cólera e da varíola, que vinham desordenadamente fazendo suas vítimas pela cidade. Diante disso, esta dissertação proc...

  3. The anti-tumor effect and biological activities of the extract JMM6 from the stem-barks of the Chinese Juglans mandshurica Maxim on human hepatoma cell line BEL-7402.

    Science.gov (United States)

    Zhang, Yongli; Cui, Yuqiang; Zhu, Jiayong; Li, Hongzhi; Mao, Jianwen; Jin, Xiaobao; Wang, Xiangsheng; Du, Yifan; Lu, Jiazheng

    2013-01-01

    Juglans mandshurica Maxim is a traditional herbal medicines in China, and its anti-tumor bioactivities are of research interest. Bioassay-guided fractionation method was employed to isolate anti-tumor compounds from the stem barks of the Juglans mandshurica Maxim. The anti-tumor effect and biological activities of the extracted compound JMM6 were studied in BEL-7402 cells by MTT, Cell cycle analysis, Hoechst 33342 staining, Annexin V-FITC/PI assay and Detection of mitochondrial membrane potential (ΔΨm). After treatment with the JMM6, the growth of BEL-7402 cells was inhibited and cells displayed typical morphological apoptotic characteristics. Further investigations revealed that treatment with JMM6 mainly caused G2/M cell cycle arrest and induced apoptosis in BEL-7402 cells. To evaluate the alteration of mitochondria in JMM6 induced apoptosis. The data showed that JMM6 decreased significantly the ΔΨm, causing the depolarization of the mitochondrial membrane. Our results show that the JMM6 will have a potential advantage of anti-tumor, less harmful to normal cells. This paper not only summarized the JMM6 pick-up technology from Juglans mandshurica Maxim and biological characteristic, but also may provide further evidence to exploit the potential medicine compounds from the stem-barks of the Chinese Juglans mandshurica Maxim.

  4. Serological Evidence of HTLV-I and HTLV-II Coinfections in HIV-1 Positive Patients in Belém, State of Pará, Brazil

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    Vallinoto ACR

    1998-01-01

    Full Text Available The occurrence of HTLV-I/II and HIV-1 coinfections have been shown to be frequent, probably in consequence of their similar modes of transmission. This paper presents the prevalence of coinfection of HTLV among HIV-1 infected and AIDS patients in Belém, State of Pará, Brazil. A group of 149 patients attending the AIDS Reference Unit of the State Department of Health was tested for the presence of antibodies to HTLV-I/II using an enzyme immunoassay and the positive reactions were confirmed with a Western blot that discriminates between HTLV-I and HTLV-II infections. Four patients (2.7% were positive to HTLV-I, seven (4.7% to HTLV-II and one (0.7% showed an indeterminate pattern of reaction. The present results show for the first time in Belém not only the occurrence of HTLV-II/HIV-1 coinfections but also a higher prevalence of HTLV-II in relation to HTLV-I. Furthermore, it also enlarges the geographical limits of the endemic area for HTLV-II in the Amazon region of Brazil.

  5. First detection of a human astrovirus type 8 in a child with diarrhea in Belém, Brazil: comparison with other strains worldwide and identification of possible three lineages

    Directory of Open Access Journals (Sweden)

    Yvone B Gabbay

    2007-06-01

    Full Text Available This study describes the genetic relationships of the first human astrovirus type-8 (HAstV-8 detected in Belém-Brazil, during a public hospital-based study. This strain was compared with other HAstV-8 strains identified elsewhere which have sequences available at GeneBank. The regions ORF1a (primers Mon348/Mon340 and ORF2 (primers Mon269/Mon270 were analyzed by nucleotide sequencing and a high similarity rate was observed among the Belém strain and other HAstV-8 strains. In ORF1a, homology values of 93-100% were detected, and in ORF2 96-99%. Considering the sequence variation (7% observed in ORF2 region, it was suggested that HAstV-8 strains could be divided in three different lineages.

  6. Logistics improvements in a cooperative of recyclable waste collectors in Belém-PA: A proposal based on NSWP

    Directory of Open Access Journals (Sweden)

    Emmily Caroline Cabral da Fonseca

    2017-03-01

    Full Text Available The increase in consumption has contributed to the growth in solid waste generation. In 2012, Brazil presented an increase in waste generation rates, which exceeded the rate of population growth. The metropolitan region of Belém-PA reflects this scenario as well. This Brazilian State has taken actions in order to combat this problem, and one of them was the creation of the National Solid Waste Policy (NSWP established by Law No. 12,305 (2010. This Law contains guidelines for handling, decreasing generation, reusing and recycling solid waste. In this sense, the cooperatives of recyclable waste collectors are an important link in this reusing and recycling network. Thus, this paper proposes improvements for the processes performed by a cooperative of waste collectors, located in Belém-PA, in the context of the NSWP by encouraging the sustainable development of this organization. For this purpose, the theoretical background was provided from journals and government sites, especially topics regarding to the said Act and the Reverse Logistics (RL. In addition, data from the cooperative activities were collected and analyzed, which resulted in the following contributions: proposition of improvements in the processes, object of this study, which followed the NSWP considerations. These results proposed actions aligned to the principles of sustainable development expected in the NSWP, as well as to generate new content focused on the area of Production Engineering, especially Logistics.

  7. Inclusão digital de professores nas escolas públicas da região metropolitana de Belém

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    Dayvid Gomes Vital Fares

    2016-02-01

    Full Text Available Este artigo traz algumas contribuições, de cunho teórico, a respeito da inclusão digital de docentes e gestores nas escolas de Belém, e as dificuldades que os mesmo encontram para utilizar a tecnologia da informação e comunicação no ambiente estudantil. Aborda sobre a infraestrutura computacional adquirida por projetos governamentais e faz uma alusão a dificuldade dos professores em relação a formação relacionada ao uso das tecnologias.

  8. "Falsifiability is not optional": Correction to LeBel et al. (2017).

    Science.gov (United States)

    2017-11-01

    Reports an error in "Falsifiability is not optional" by Etienne P. LeBel, Derek Berger, Lorne Campbell and Timothy J. Loving ( Journal of Personality and Social Psychology , 2017[Aug], Vol 113[2], 254-261). In the reply, there were two errors in the References list. The publishing year for the 14th and 21st articles was cited incorrectly as 2016. The in-text acronym associated with these citations should read instead as FER2017 and LCL2017. The correct References list citations should read as follows, respectively: Finkel, E. J., Eastwick, P. W., & Reis, H. T. (2017). Replicability and other features of a high-quality science: Toward a balanced and empirical approach. Journal of Personality and Social Psychology , 113, 244-253. http://dx.doi.org/10.1037/pspi0000075 LeBel, E. P., Campbell, L., & Loving, T. J. (2017). Benefits of open and high-powered research outweigh costs. Journal of Personality and Social Psychology , 113, 230-243. http://dx.doi.org/10 .1037/pspi0000049. The online version of this article has been corrected. (The following abstract of the original article appeared in record 2017-30567-003.) Finkel, Eastwick, and Reis (2016; FER2016) argued the post-2011 methodological reform movement has focused narrowly on replicability, neglecting other essential goals of research. We agree multiple scientific goals are essential, but argue, however, a more fine-grained language, conceptualization, and approach to replication is needed to accomplish these goals. Replication is the general empirical mechanism for testing and falsifying theory. Sufficiently methodologically similar replications, also known as direct replications, test the basic existence of phenomena and ensure cumulative progress is possible a priori. In contrast, increasingly methodologically dissimilar replications, also known as conceptual replications, test the relevance of auxiliary hypotheses (e.g., manipulation and measurement issues, contextual factors) required to productively

  9. USO DO SOLO E DEGRADAÇÃO AMBIENTAL: estudo de caso da bacia do Mata Fome em Belém, Pará

    Directory of Open Access Journals (Sweden)

    Marcos Jonatas Damasceno da Silva

    2016-12-01

    There are several problems present in the spaces of brazilian cities, especially in large urban areas. One such problem is the degradation of the environment due to unplanned interventions in these spaces. In this sense, this work aims to analyze the relationship between the production of urban space that assigns different uses to soil and environmental degradation in the Mata Fome Watershed in Belém, Pará. In addition, we carried out a mapping of the use of soil of the study area where the satellite image Ikonos 2006. The results of this study indicated that the production of urban space in Mata Fome Watershed and various land uses, caused environmental degradation was used to trigger the destruction of vegetation, water pollution and soil changes in the topography of the land, floods, health risks and other damage. Keywords: Environment; Urbanization; Hydrographic watershed; Pollution. USO DEL SUELO Y DEGRADACIÓN AMBIENTAL: estudio del caso de la cuenca del Mata Fome en Belém, Pará RESUMEN Hay varios problemas presentes en los espacios de las ciudades brasileñas, especialmente en las grandes áreas urbanas. Uno de estos problemas es la degradación del medio ambiente debido a las intervenciones no planificadas en estos espacios. En este sentido, este trabajo tiene como objetivo analizar la relación entre la producción del espacio urbano, que asigna a los diferentes usos del suelo y la degradación del medio ambiente en la Cuenca del Mata Fome en Belém, Pará. Además, se realizó un mapeo del uso del suelo de la zona de estudio, donde la imagen de satélite Ikonos 2006. Los resultados de este estudio indicaron que la producción del espacio urbano en la Cuenca del Mata Fome y diversos usos de la tierra causado la degradación ambiental se utilizó para desencadenar la destrucción de la vegetación, la contaminación del agua y los cambios de suelo en la topografía del terreno, inundaciones, riesgos para la salud, y otros daños. Palabras clave: Medio

  10. How the redox state of tobacco 'Bel-W3' is modified in response to ozone and other environmental factors in a sub-tropical area?

    International Nuclear Information System (INIS)

    Dias, Ana P.L.; Dafre, Marcelle; Rinaldi, Mirian C.S.; Domingos, Marisa

    2011-01-01

    This study intended to determine whether the redox state in plants of Nicotiana tabacum 'Bel-W3' fluctuates in response to the environmental factors in a sub-tropical area contaminated by ozone (Sao Paulo, SE - Brazil) and which environmental factors are related to this fluctuation, discussing their biomonitoring efficiency. We comparatively evaluated the indicators of redox state (ascorbic acid, glutathione, superoxide dismutase, ascorbate peroxidase, and glutathione reductase) and leaf injury in 17 field experiments performed in 2008. The redox state was explained by the combined effects of chronic levels of O 3 and meteorological variables 4-6 days prior to the plant sampling. Moderate leaf injury was observed in most cases. The redox state of tobacco decreases few days after their placement in the sub-tropical environment, causing them to become susceptible to oxidative stress imposed by chronic doses of O 3 . Its bioindicator efficiency would not be diminished in such levels of atmospheric contamination. - Research highlights: → Nicotiana tabacum 'Bel-W3' is potentially a bioindicator of O 3 in the sub-tropics. → However, it is unknown if its redox state would affect its bioindicator performance under sub-tropical environmental conditions. → This study revealed that the redox state of tobacco decreases few days after their placement in the sub-tropical environment, causing them to become susceptible to oxidative stress imposed by chronic doses of O 3 . → Therefore, its bioindicator efficiency would not be diminished in such levels of atmospheric contamination. → However, the bioindicator efficiency N. tabacum 'Bel-W3' for biomonitoring O 3 should be regionally modeled in the sub-tropics, based on both its redox state and on the flux of O 3 through stomata, in response to the varying micro-meteorological conditions that govern both physiological processes. - The bioindicator efficiency of tobacco plants is not restrained under chronic doses of O 3 in

  11. Evaluation of four techniques for diagnosis of Giardia lamblia in children's stool from Belém city, Para State, Brazil

    OpenAIRE

    Machado, Ricardo Luiz Dantas; Figueredo, Maria Cristina; Frade, Amanda Farage; Kudó, Mônica Eriko; Silva Filho, Manoel Gomes; Póvoa, Marinete Marins

    2001-01-01

    Relatamos a comparação de quatro metodologias para o diagnóstico da Giardia lamblia em material fecal de crianças, Belém/PA. A Hematoxilina Férrica e o método direto apresentaram menor positividade, enquanto que o Método de Faust continua uma boa escolha para o diagnóstico e o Ensaio imunoenzimático melhora a qualidade da detecção deste parasito.We report the evaluation of four techniques for Giardia lamblia diagnosis in children's stool. The Iron haematoxilin staining and direct examination ...

  12. Unreliable Yet Still Replicable: A Comment on LeBel and Paunonen (2011)

    Science.gov (United States)

    De Schryver, Maarten; Hughes, Sean; Rosseel, Yves; De Houwer, Jan

    2016-01-01

    Lebel and Paunonen (2011) highlight that despite their importance and popularity in both theoretical and applied research, many implicit measures continue to be plagued by a persistent and troublesome issue—low reliability. In their paper, they offer a conceptual analysis of the relationship between reliability, power and replicability, and then provide a series of recommendations for researchers interested in using implicit measures in an experimental setting. At the core of their account is the idea that reliability can be equated with statistical power, such that “lower levels of reliability are associated with decreasing probabilities of detecting a statistically significant effect, given one exists in the population” (p. 573). They also take the additional step of equating reliability and replicability. In our commentary, we draw attention to the fact that there is no direct, fixed or one-to-one relation between reliability and power or replicability. More specifically, we argue that when adopting an experimental (rather than a correlational) approach, researchers strive to minimize inter-individual variation, which has a direct impact on sample based reliability estimates. We evaluate the strengths and weaknesses of the LeBel and Paunonen's recommendations and refine them where appropriate. PMID:26793150

  13. How the redox state of tobacco 'Bel-W3' is modified in response to ozone and other environmental factors in a sub-tropical area?

    Energy Technology Data Exchange (ETDEWEB)

    Dias, Ana P.L.; Dafre, Marcelle; Rinaldi, Mirian C.S. [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil); Domingos, Marisa, E-mail: mmingos@superig.com.b [Instituto de Botanica, Caixa Postal 3005, 01061-970 Sao Paulo, SP (Brazil)

    2011-02-15

    This study intended to determine whether the redox state in plants of Nicotiana tabacum 'Bel-W3' fluctuates in response to the environmental factors in a sub-tropical area contaminated by ozone (Sao Paulo, SE - Brazil) and which environmental factors are related to this fluctuation, discussing their biomonitoring efficiency. We comparatively evaluated the indicators of redox state (ascorbic acid, glutathione, superoxide dismutase, ascorbate peroxidase, and glutathione reductase) and leaf injury in 17 field experiments performed in 2008. The redox state was explained by the combined effects of chronic levels of O{sub 3} and meteorological variables 4-6 days prior to the plant sampling. Moderate leaf injury was observed in most cases. The redox state of tobacco decreases few days after their placement in the sub-tropical environment, causing them to become susceptible to oxidative stress imposed by chronic doses of O{sub 3}. Its bioindicator efficiency would not be diminished in such levels of atmospheric contamination. - Research highlights: Nicotiana tabacum 'Bel-W3' is potentially a bioindicator of O{sub 3} in the sub-tropics. However, it is unknown if its redox state would affect its bioindicator performance under sub-tropical environmental conditions. This study revealed that the redox state of tobacco decreases few days after their placement in the sub-tropical environment, causing them to become susceptible to oxidative stress imposed by chronic doses of O{sub 3}. Therefore, its bioindicator efficiency would not be diminished in such levels of atmospheric contamination. However, the bioindicator efficiency N. tabacum 'Bel-W3' for biomonitoring O{sub 3} should be regionally modeled in the sub-tropics, based on both its redox state and on the flux of O{sub 3} through stomata, in response to the varying micro-meteorological conditions that govern both physiological processes. - The bioindicator efficiency of tobacco plants is not

  14. Determinação da infecção por Entamoeba histolytica em residentes da área metropolitana de Belém, Pará, Brasil, utilizando ensaio imunoenzimático (ELISA para detecção de antígenos Determination of Entamoeba histolytica infection in patients from Greater Metropolitan Belém, Pará, Brazil, by enzyme-linked immunosorbent assay (ELISA for antigen detection

    Directory of Open Access Journals (Sweden)

    Mônica Cristina de Moraes Silva

    2005-06-01

    Full Text Available O status epidemiológico da amebíase está sendo reavaliado desde que a Entamoeba histolytica (patogênica foi considerada espécie distinta de Entamoeba dispar (não patogênica. Em nosso estudo, realizamos pesquisa de antígenos de E. histolytica em amostras fecais de pacientes residentes na cidade de Belém, Pará, Brasil, utilizando ensaio imunoenzimático (E. histolytica Test, TechLab Inc., Blacksburg, Estados Unidos disponível comercialmente. Foram analisadas 845 amostras, com positividade em 248 (29,35%. A infecção por E. histolytica foi maior no grupo etário acima de 14 anos (30,36% que no grupo de 0-14 anos (28,28%, porém sem significância estatística (p The epidemiological status of amebiasis has been reevaluated since Entamoeba histolytica (pathogenic was considered a distinct species from Entamoeba dispar (non-pathogenic. We investigated E. histolytica antigens in stool samples from residents of Belém, Pará State, Brazil, with commercially available enzyme-linked immunosorbent assay (E. histolytica Test, TechLab Inc., Blacksburg, USA. A total of 845 samples were analyzed, of which 248 were positive (29.35%. E. histolytica infection was more frequent in the over-14-year age group (30.36% than in the 0-14-year group (28.28%, but the difference was not statistically significant (p < 0.05. Of all the samples, 334 were also submitted to parasitological methods (direct, Hoffman, and Faust et al.. There were discordant results between ELISA and parasitological methods in 83 samples (24.85%, with more positive results using ELISA. Our results thus suggest that intestinal amebiasis is an important public health problem in Greater Metropolitan Belém.

  15. Teores de nitrato (NO3- e amônio (NH4+ nas águas do aqüífero Barreiras nos bairros do Reduto, Nazaré e Umarizal - Belém/PA Nitrate (NO3- and ammonium (NH4+ contents in the Barreiras aquifer waters in the districts of Reduto, Nazaré and Umarizal - Belém, PA

    Directory of Open Access Journals (Sweden)

    Natalina Maria Tinôco Cabral

    2007-01-01

    Full Text Available This paper evaluates the occurrence of nitrate and ammonium in the Barreiras aquifer in the metropolitan area of Belém, Pará State, Brazil. The results show that some wells display ammonium and nitrate concentrations above or close to the limits of water potability regulations. The main cause of the pollution of these waters is related the local disposal of domestic effluents and/or leakage from pipes of old sewage systems.

  16. Combining Public Domain and Professional Panoramic Imagery for the Accurate and Dense 3d Reconstruction of the Destroyed Bel Temple in Palmyra

    Science.gov (United States)

    Wahbeh, W.; Nebiker, S.; Fangi, G.

    2016-06-01

    This paper exploits the potential of dense multi-image 3d reconstruction of destroyed cultural heritage monuments by either using public domain touristic imagery only or by combining the public domain imagery with professional panoramic imagery. The focus of our work is placed on the reconstruction of the temple of Bel, one of the Syrian heritage monuments, which was destroyed in September 2015 by the so called "Islamic State". The great temple of Bel is considered as one of the most important religious buildings of the 1st century AD in the East with a unique design. The investigations and the reconstruction were carried out using two types of imagery. The first are freely available generic touristic photos collected from the web. The second are panoramic images captured in 2010 for documenting those monuments. In the paper we present a 3d reconstruction workflow for both types of imagery using state-of-the art dense image matching software, addressing the non-trivial challenges of combining uncalibrated public domain imagery with panoramic images with very wide base-lines. We subsequently investigate the aspects of accuracy and completeness obtainable from the public domain touristic images alone and from the combination with spherical panoramas. We furthermore discuss the challenges of co-registering the weakly connected 3d point cloud fragments resulting from the limited coverage of the touristic photos. We then describe an approach using spherical photogrammetry as a virtual topographic survey allowing the co-registration of a detailed and accurate single 3d model of the temple interior and exterior.

  17. Gentrificação e resistência popular nas feiras e portos públicos da Estrada Nova em Belém (PA

    Directory of Open Access Journals (Sweden)

    Jakson Silva da Silva

    Full Text Available Resumo Este artigo considera a resistência popular nas feiras e portos públicos da Estrada Nova, atual av. Bernardo Sayão. Interpreta a ocupação da parte sul da orla de Belém, analisada em termos da produção social do espaço urbano. A resistência popular busca manter os portos públicos da Palha e do Açaí como lugar de trocas econômicas e culturais múltiplas, contra a intenção do poder público municipal de ‘gentrificar’ ou enobrecer essa margem urbana da cidade, removendo os atuais usuários, mediante o projeto denominado Portal da Amazônia. A resistência de feirantes, trabalhadores e moradores contrapõe a metáfora ‘janelas para o rio’, que funciona como uma espécie de pensamento único na cidade, com outra metáfora, a de ‘portas para o rio’, que diz respeito à necessidade de ir e vir dos ribeirinhos, que reivindicam seu direito à cidade. O movimento de pessoas e mercadorias nos portos e redondezas configura um espaço de economia e vida popular em Belém. Esse movimento proporciona identidade aos bairros do Jurunas, Condor e Guamá e condiz com preceitos urbanísticos recomendados por autores como Jane Jacobs e Marshall Berman, que valorizam a vida cotidiana da rua. O projeto avança de forma obscura, sem qualquer critério de diálogo e transparência.

  18. Outbreaks of human-herpes virus 6 (HHV-6 infection in day-care centers in Belém, Pará, Brazil

    Directory of Open Access Journals (Sweden)

    FREITAS Ronaldo B.

    2000-01-01

    Full Text Available A total of 730 children aged less than 7 years, attending 8 day-care centers (DCCs in Belém, Brazil were followed-up from January to December 1997 to investigate the occurrence of human-herpes virus 6 (HHV-6 infection in these institutional settings. Between October and December 1997 there have been outbreaks of a febrile- and -exanthematous disease, affecting at least 15-20% of children in each of the DCCs. Both serum- and- plasma samples were obtained from 401 (55% of the 730 participating children for the detection of HHV-6 antibodies by enzyme-linked immunosorbent assay (ELISA, and viral DNA amplification through the nested-PCR. Recent HHV-6 infection was diagnosed in 63.8% (256/401 of them, as defined by the presence of both IgM and IgG-specific antibodies (IgM+/IgG+; of these, 114 (44.5% were symptomatic and 142 (55.5% had no symptoms (p = 0.03. A subgroup of 123 (30.7% children were found to be IgM-/IgG+, whereas the remaining 22 (5.5% children had neither IgM nor IgG HHV-6- antibodies (IgM-/IgG-. Of the 118 children reacting strongly IgM-positive ( > or = 30 PANBIO units, 26 (22.0% were found to harbour the HHV-6 DNA, as demonstrated by nested-PCR. Taken the ELISA-IgM- and- nested PCR-positive results together, HHV-6 infection was shown to have occurred in 5 of the 8 DCCs under follow-up. Serological evidence of recent infections by Epstein-Barr virus (EBV and parvovirus B19 were identified in 2.0% (8/401 and 1.5% (6/401 of the children, respectively. Our data provide strong evidence that HHV-6 is a common cause of outbreaks of febrile/exanthematous diseases among children attending DCCs in the Belém area.

  19. Análise discriminante múltipla do mercado varejista de açaí em Belém do Pará

    OpenAIRE

    Santana, Antônio Cordeiro de; Santana, Ádamo Lima de; Santana, Ádina Lima de; Santos, Marcos Antônio Souza dos; Oliveira, Cyntia Meireles de

    2014-01-01

    O açaí é um dos principais alimentos da população paraense e de maior consumo per capita em 2010. A venda de açaí em Belém é realizada por diversas unidades que operam no mercado varejista. O objetivo deste trabalho foi identificar os segmentos de mercado: quitandas, microempreendedores e supermercados, a partir da análise de um conjunto de variáveis que definem as decisões dos consumidores de açaí. Utilizou-se do método stepwise da análise discriminante múltipla para estimar as funções discr...

  20. Remediación del derrame de hidrocarburos en el caso Barreal-Belén, Costa Rica

    Directory of Open Access Journals (Sweden)

    Luis Carlos Vargas Fallas

    2009-11-01

    Full Text Available Se presenta el estado de avance en la atención del caso de derrame dehidrocarburos ocurrido en Barreal-Belén, Costa Rica, consistente en la fuga de cerca de 30.000 litros compuestos por gasolina y diesel, que están contenidos en un acuífero colgado ubicado a una profundidad de 20 a 22 metros. A este acuífero le subyace una capa de toba calcinada que ha funcionado como un sello e impedido el flujo hacia los acuíferos colima que le subyacen y que son utilizados para el abastecimiento de poblaciones.Se presenta la estrategia de trabajo para lograr la remediación establecida por la Comisión Interinstitucional en el 2005. A dos meses de iniciados los procesos extractivos, se presenta las medidas adoptadas para separar los hidrocarburos de las aguas y se establece un pronóstico en años de operación, de acuerdo con dos posibles escenarios de limpieza.

  1. As Práticas Turísticas na Orla Oeste da Ilha de Mosqueiro, Região Metropolitana de Belém, PA

    Directory of Open Access Journals (Sweden)

    Willame de Oliveira Ribeiro

    2013-10-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE MicrosoftInternetExplorer4 A Ilha do Mosqueiro pertence ao município de Belém, mas localiza-se a 77 km da sua sede. A Ilha teve seu processo de valorização para o Turismo iniciado no período áureo da economia da borracha e se acelerou com a implantação da ponte ligando-a ao continente, durante a década de 1970. Este artigo objetiva apresentar as práticas turísticas na orla oeste da Ilha de Mosqueiro, identificando o processo de des-re-territorialização de tais práticas e o viés do [eco] turismo como uma possibilidade de nova significação ao uso da orla oeste da ilha.  Tourist Practices in Waterfront West Island Mosqueiro, metropolitan region of Belém, PA, Brazil - The island Mosqueiro belonging to the municipality of Belem and it is located 77 km from the capital. The process for introduction of tourism practice started in the heyday of the rubber economy and it was accelerated during the 1970s with the build of the bridge connecting the island to the mainland. This article presents the tourism practices on the west of the Ilha do Mosqueiro, identifying the its process of de-re- territorialization and the [eco] tourism as a possibility for new meaning to the use of the western edge of the island.  

  2. Mesostructural observations along the Western coast of Bel'kovsky Island: preliminary results (North-Eastern Laptev Sea region, Russian Arctic)

    Science.gov (United States)

    Verzhbitsky, V. E.

    2003-04-01

    This study is based on the field works carried out by the Institute of the Lithosphere of Marginal Seas RAS in the central part of the Bel'kovsky island during 2002 August-September. In the tectonic sense the Bel'kovsky island is located in the eastern part of the Late Cretaceous (?) - Cenozoic Laptev Sea rift system and also is a part of extended Bel’kov horst, dividing Bel’kov Svyatoi Nos (in the east) and Anisin (in the west) rifts (e.g. Drachev et al, 1998). Mesostructural investigations included statistical measurments of kinematic indicators (cleavage planes, extensional veins, slickensides, axes of folds and bedding plains) in Devonian and Carboniferous sedimentary formations and also slickensides in diabase magmatic complex (presumably of Late Paleozoic age). It is supposed, that this studies will allow to characterize the stages of regional tectonic processes: synsedimentary (slump) folds formation (1), NE-SW compression (2), which corresponds to the general (NW-SE trending) structural pattern of the island, E-W compression (3), expressed in N-S trending subvertical cleavage and associated strike-slips and thrust faults, NW-SE (4) and ENE-WSW - NE-SW (5) extension, expressed in strike-slip faults with different strike-slip component, and also, probably to specify the character of the recent tectonic processes near to the area of conjunction between the Eurasian and American plates. It is likely, that synsedimentary (slump) folds, identified in the Carboniferous clastic formation marks the paleoslope setting of New Siberian Islands Chukotka platform (block). Presumably, second of the determined stages corresponds to closing of the South Anyui Lyakhov paleooceanic basin in Neocomian; the last stage, expressed in wide-developed submeridional normal faults with sinistral strike-slip component along the western coast of the island, reflects the modern regional stress-field in area of conjunction between the Eurasian and American plates (e.g. Avetisov, 1999

  3. Actividad hidráulica de un cemento belítico obtenido a partir de cenizas volantes tipo C: influencia del aditivo y tipo de curado

    OpenAIRE

    Goñi Elizalde, Sara; Guerrero Bustos, Ana María

    2006-01-01

    En este trabajo se discute la influencia del tipo de curado y de un aditivo reductor de la demanda de agua en la actividad hidráulica de un cemento belítico de cenizas volantes de alto contenido en cal denominado (CBCV-2-A). Este cemento ha sido sintetizado por una ruta húmeda hidrotermal con posterior calcinación, empleando ceniza volante de alto contenido en cal (ASTM tipo C) como materia prima. La actividad hidráulica se ha estudiado en la pasta de cemento, durante un periodo de 180 ...

  4. Prevalência e fatores associados à deficiência de ferro em lactentes atendidos em um centro de saúde-escola em Belém, Pará, Brasil Prevalence and factors associated with iron deficiency in infants treated at a primary care center in Belém, Pará, Brazil

    Directory of Open Access Journals (Sweden)

    Márcia Bitar Portella Neves

    2005-12-01

    Full Text Available Determinar a prevalência de deficiência de ferro e fatores associados em lactentes. Neste estudo transversal, foram estudados 365 lactentes atendidos em um centro de saúde-escola, em Belém, Pará, Brasil. Anemia ferropriva (hemoglobina 11g/dl e ferritina 11g/dl e ferritina > 12µg/l, em 18,1%. Em 12,5% dos lactentes, não incluídos na avaliação dos fatores associados com a deficiência de ferro, encontraram-se hemoglobina 12µg/l. Os resultados do modelo de regressão logística mostraram associação entre deficiência de ferro (ferritina The objective was to verify the occurrence of iron deficiency and associated factors in infants. This cross-sectional study included 365 infants (defined here as 6-24 months of age treated at a primary care center in Belém, Pará, Brazil. Iron-deficiency anemia (hemoglobin < 11g/dl and ferritin < 12µg/l was diagnosed in 55.1% of the sample, depletion of body iron reserves (hemoglobin < 11g/dl and ferritin < 12µg/l in 15.3%, and iron sufficiency (hemoglobin < 11g/dl and ferritin < 12µg/l in 18.1%. The results of the logistic regression model showed associations between iron deficiency (ferritin < 12µg/l and: 6-12 month age group, OR (odds ratio = 3.67 and 95% CI: 1.93-7.04; non-utilization of iron-fortified formula as the first milk used after interrupting breastfeeding, OR = 1.93 and 95%CI: 1.04-3.60; and per capita income ¾ 1 minimum wage, OR = 2.69 and 95%CI: 1.30-5.59. The occurrence of iron deficiency was high, showing the need to adopt effective measures to prevent this important public health problem.

  5. Diversidade de bromeliáceas epífitas na Área de Proteção Ambiental Ilha do Combu, Belém, Pará, Brasil Diversity of epiphytic bromeliads in the environmental protection area of Combu Island, Belém, Pará, Brazil

    Directory of Open Access Journals (Sweden)

    Adriano Costa Quaresma

    2012-06-01

    Full Text Available Informações sobre a diversidade no nível de espécie oferecem subsídios importantes para o desenvolvimento sustentável e a conservação biológica. Neste contexto, estudos com Bromeliaceae merecem destaque, especialmente porque o grupo é importante ecologicamente, mas ainda pouco conhecido na Região Norte. Neste trabalho, foram demarcadas duas parcelas de 100 m x 100 m em uma floresta de várzea localizada na Área de Proteção Ambiental Ilha do Combu, em Belém, Estado do Pará. Cada parcela foi subdividida em oito parcelas de 50 m x 50 m, tendo todas as espécies e espécimes de bromeliáceas epífitas registradas e quantificadas. A diversidade do grupo foi calculada utilizando o índice de Shannon-Wiener. Foram registrados 1.339 indivíduos pertencentes a oito espécies e quatro gêneros. Tillandsia e Aechmea apresentaram maior riqueza. A diversidade de espécies na área foi de H= 1,10, apresentando dominância acentuada de muitos indivíduos em poucas espécies.Information about diversity at the species level offers data for sustainable development and biological conservation. In this context, studies about Bromeliaceae are noteworthy, especially because this group is ecologically important and poorly known in the North Region of Brazil. In this study, two grids (100 m x 100 m were delineated in a floodplain forest in the environmental protection area of Combu Island, Belém, Pará, Brazil. The grids were subdivided into eight grids of 50 m x 50 m, and all species and individuals of epiphytic Bromeliaceae were recorded and quantified. The diversity was calculated using the Shannon-Wiener index. A total of 1,339 individuals, belonging to eight species and four genera were recorded. Tillandsia and Aechmea presented the greatest richness. The diversity of species was H= 1.10, presenting sharp dominance of many individuals of few species.

  6. Capacidade funcional de idosos atendidos em um programa do SUS em Belém (PA Functional capacity of the elderly attended in a Unified Health System (SUS program in Belém in the State of Pará

    Directory of Open Access Journals (Sweden)

    Maria Izabel Penha de Oliveira Santos

    2013-03-01

    Full Text Available O objetivo deste estudo foi avaliar fatores associados à capacidade funcional em idosos atendidos em um programa de saúde pública em Belém (PA. Realizou-se estudo seccional com 259 idosos atendidos no programa Hiperdia/SUS no período de março a julho de 2010. Os idosos foram avaliados pelo teste de desempenho físico modificado, validado no Brasil. Nas análises foram utilizados o teste do qui-quadrado de Pearson, a análise de variância e a regressão. Os idosos tinham em média 68,3 anos (DP ± 6,2 e 71,0% eram do sexo feminino. Após ajustes por variáveis de confundimento, observaram-se maiores chances de pior desempenho no teste entre as mulheres, os mais velhos e os de menor escolaridade, além de queixa de dor no joelho, diagnóstico anterior de catarata e autoavaliação de saúde regular/ruim. A capacidade funcional é um indicador de saúde importante para se identificar precocemente riscos de incapacidade e requerendo uma avaliação periódica, no intuito de se buscar estratégias cuidativas para a manutenção da independência dos idosos.The objective of this study was to evaluate factors associated with functional capacity among the elderly attended in a public health program in Belém in the State of Pará. A sectional study was conducted with 259 elderly people attended in the Hiperdia/SUS program in the period from March to July 2010. The elderly were assessed using the modified physical performance test duly validated in Brazil. Pearson's Chi-square Test, in addition to variance analysis and logistic regression were used for the analysis. The elderly were 68.3 years on average (SD ± 6.2 and 71% were female. After adjustments for conflicting variables, it was seen that there were greater chances of worse performance on the test among women, the older and less educated individuals, and those complaining of knee pain and prior diagnosis of cataracts and fair/bad self-assessment of health. Functional capacity is an

  7. Pedra do Peixe: redes sociais na circulação do pescado do Ver-o-Peso para a cidade de Belém do Pará

    Directory of Open Access Journals (Sweden)

    Luiz de Jesus Dias da Silva

    Full Text Available Resumo Este artigo tem por objetivo apresentar uma etnografia sobre a rede social envolvida no processo de circulação do pescado que chega diariamente ao mercado do Ver-o-Peso, principal entreposto pesqueiro da região amazônica, e é distribuído por toda a cidade de Belém do Pará. Diariamente, o pescado in natura, capturado e trazido em embarcações pesqueiras, entra na área urbana pela Pedra do Peixe, marco espacial e simbólico do mercado do Ver-o-Peso,no qual é vendido e distribuído na cidade e para outras praças do estado e do país, para chegar aos consumidores finais, que o encontram nas feiras, mercados, supermercados e outros pontos de venda, assim como nos restaurantes diversificados, em forma de pratos regionais preparados para os muitos apreciadores do produto. Essa extensa rede de comercialização do pescado apresenta aspectos econômicos, sociais, culturais, regras, informalidades e conflitos, que fazem com que a circulação do pescado em Belém permaneça, até a atualidade, com muito vigor, tendo a Pedra do Ver-o-Peso como centralidade do seu fluxo cotidiano, através das redes de relações e das práticas socioculturais incorporadas por trabalhadores e fregueses que circulam diariamente por esse espaço central da cidade.

  8. Spiked pepper: selection of clones toward cropping on the edaphoclimatic conditions from Belém, Brazil Pimenta-de-macaco: seleção de clones para plantio nas condições edafoclimáticas de Belém

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    José Maria D Gaia

    2010-12-01

    Full Text Available Spiked pepper presents a high yield of essential oil with useful biological properties for human health and agriculture. In order to evaluate the morphoagronomic variability and, afterwards, to select genotypes for plant breeding and cultivation, thirteen clones were propagated. Thus, spiked pepper cuttings were rooted under greenhouse, transferred to a nursery and, afterwards, planted at the experimental area. The evaluations were carried out in two harvest seasons. The evaluated morphoagronomic traits were number of leaves per branch, leaf length, leaf width, diameter of the oldest branch, plant height, number of orthotropic branches, number of plagiotropic branches, internode length, fresh and dry matter, yield of essential oil and dillapiole content. The analysis of variance and the Scott-Knott test were utilized for data analysis and comparisons among clones and parentals were carried out through genetic and experimental variation coefficients. Fresh matter (first season, number of orthotropic branches and diameter of the the oldest branch (second season presented variability. The Scott-Knott test detected variability for fresh matter, dillapiole content (first season, diameter of the oldest branch and number of orthotropic branches (second season. The yield of essential oil and the dillapiole content were higher for the clones than for the parentals. In conclusion, the clones showed adaptability to the soil and climate conditions of Belém, Pará State, Brazil; the harvest time influenced the oil yield and the dillapiole content; the variance analysis evidenced uniformity and productivity for the evaluated clones, suggesting they can be recommended for cultivation on small-scale production systems in this location.Pimenta-de-macaco é uma espécie com elevado teor de óleo essencial em que se constatam propriedades biológicas utilizáveis na agricultura e saúde humana. Com o objetivo de avaliar a variabilidade morfoagronômica e

  9. Teatro da Paz: histórias invisíveis em Belém do grão-Pará

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    Roseane Silveira de Souza

    2010-01-01

    Full Text Available Teatro da Paz ("Peace Theater", in Belém, capital of State of Pará, is one of the most representative neo-classical opera houses in brazil. Its remarkable history and features resulted of a deep process of architectonic renewal occurred between 1904 and 1905, when it had also a sort of rich elements of decoration incorporated. As a result, the process hidden facts happened from the building (1869-1878, following by the opening and functioning (1878-1887, until the first important renovation (1887-1890, involving improper management of public sources, conflicts between engineers, litigations, the intense public uses for nine years and the participation of two recognized artists, the Italian Domenico de Angelis and the brazilian Chrispim do Amaral, in the first renovation. Uncovering these invisible histories, outsider histories, give to monument back its human, social dimension.

  10. Comparação de quatro métodos laboratoriais para diagnóstico da Giardia lamblia em fezes de crianças residentes em Belém, Pará

    OpenAIRE

    Machado,Ricardo Luiz Dantas; Figueredo,Maria Cristina; Frade,Amanda Farage; Kudó,Mônica Eriko; Silva Filho,Manoel Gomes; Póvoa,Marinete Marins

    2001-01-01

    Relatamos a comparação de quatro metodologias para o diagnóstico da Giardia lamblia em material fecal de crianças, Belém/PA. A Hematoxilina Férrica e o método direto apresentaram menor positividade, enquanto que o Método de Faust continua uma boa escolha para o diagnóstico e o Ensaio imunoenzimático melhora a qualidade da detecção deste parasito.

  11. Actividad hidráulica de un cemento belítico obtenido a partir de cenizas volantes tipo C: influencia del aditivo y tipo de curado

    OpenAIRE

    Goñi, S.; Guerrero, A.

    2006-01-01

    En este trabajo se discute la influencia del tipo de curado y de un aditivo reductor de la demanda de agua en la actividad hidráulica de un cemento belítico de cenizas volantes de alto contenido en cal denominado (CBCV-2-A). Este cemento ha sido sintetizado por una ruta húmeda hidrotermal con posterior calcinación, empleando ceniza volante de alto contenido en cal (ASTM tipo C) como materia prima. La actividad hidráulica se ha estudiado en la pasta de cemento, durante un periodo de 180 días, ...

  12. Numerical model of the catchments of the oziąbel and wołczyński strumień rivers - Wołczyn municipality

    Science.gov (United States)

    Olichwer, Tomasz; Wcisło, Marek; Staśko, Stanisław; Buczyński, Sebastian; Modelska, Magdalena; Tarka, Robert

    2012-10-01

    The article presents a numerical model designed for determining groundwater dynamics and water balance of the catchments of the Oziąbel (Czarna Woda) river and the Wołczyński Strumień river in Wołczyn region. Hydrogeological mapping and modelling research covered the area of 238.9 km2. As a result of measurements performed in 2008-2009, flows were determined in major rivers and water table positions were measured at 26 points. In the major part of the area described, the water table, lying at the depth of 1.5-18.7 m, has unconfined character, and the aquifer is built of Neogene (Quaternary) sands and gravels. In the area under study, groundwaters are drawn from 6 wells with total withdrawal of 6133 m3/d. The numerical modelling was performed with the use of Visual Modflow 3.1.0 software. The area was partitioned by a discretization grid with a step size l = 250 m. The conceptual model of the hydrogeological system is based on hydrological data gathered over a period of one year, data from HYDRO bank database, cross-sections and maps. The boundaries of the modelled hydrogeological system were established on the watersheds of the Wołczyński Strumień river and the Oziąbel river, apart from the areas where they run together. The modelled area was extended (271.5 km2) around the Wołczyński Strumień river catchment to achieve a more effective mapping of the anthropogenic impact on its balance and the hydrodynamic system of the catchment area. The structure is characterised by the occurrence of one or rarely two aquifers separated by a pack of Quaternary clays. The investigation produced a detailed water balance and its components.

  13. Dislipidemia em escolares na rede privada de Belém Dislipidemia en escolares del sistema de educación privada de la ciudad de Belém Dyslipidemia in schoolchildren from private schools in Belém

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    Simone Augusta Ribas

    2009-06-01

    Full Text Available FUNDAMENTO: Atualmente, a dislipidemia infanto-juvenil associada a outros agravos não transmissíveis como diabete, hipertensão e obesidade representam um grave problema de saúde pública no Brasil. OBJETIVO: Investigar a prevalência de dislipidemia em crianças e adolescentes da rede particular de ensino na cidade de Belém. MÉTODOS: Estudo transversal e prospectivo, no qual foram avaliados 437 escolares pareados por sexo. A faixa etária foi delimitada entre 6 a 19 anos, estratificada em quatro subgrupos (6 a 9 anos; 10 a 12 anos; 13 a 15 anos e 16 a 19 anos. Para obtenção das variáveis antropométricas foram mensurados peso e estatura, para o cálculo do índice de massa corporal; e pregas cutâneas para o cálculo do percentual de gordura. O perfil lipoprotéico sérico foi obtido através da dosagem do colesterol total, triglicerídeo, LDL-colesterol e o HDL-colesterol após 12 horas de jejum, determinado por métodos enzimáticos. RESULTADOS: Do total de escolares analisados 126 (28,8% apresentaram excesso de peso e 158 (36,2% índice de adiposidade elevado. As crianças (33,6% apresentaram maior prevalência de obesidade quando comparadas com os adolescentes (10,1% (pFUNDAMENTO: Actualmente, la dislipidemia infanto-juvenil asociada a otros trastornos no transmisibles como diabetes, hipertensión y obesidad representan un grave problema de salud pública en el Brasil. OBJETIVO: Investigar la prevalencia de dislipidemia en niños y adolescentes del sistema privado de enseñanza de la ciudad de Belém. MÉTODOS: Estudio transversal y prospectivo, en el que se evaluaron a 437 escolares pareados por sexo. El grupo de edad se limitó entre 6 y 19 años, estratificado en 4 subgrupos (6 a 9 años; 10 a 12 años; 13 a 15 años y 16 a 19 años. Para obtenerse las variables antropométricas se midieron el peso y la estatura, para el cálculo del índice de masa corporal; y pliegues cutáneos para el cálculo del porcentaje de grasa. El

  14. Urbanization and runoff in the Tucunduba hydrographic basin, Belém, PA, Brazil

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    Nelson Wellausen Dias

    2012-08-01

    Full Text Available The present work investigated the runoff resulting from urban sprawl in the area of Tucunduba basin, in Belem, in the period between 1972 and 2006, which is characterized by a urbanization process started in the 1960s by low income population without adequate infrastructure services. Urbanization modifies the soil surface interfering on the ground phase of the hydrological cycle, inasmuch as it reduces the area of infiltration, increases runoff, and the runoff coefficient. A geographic database with land use and land cover map layers extracted from orthophotos acquired in 1972, 1977, and 1998 and a SPOT satellite image acquired in 2006 were used. Digital maps and analysis of the urbanization processes were supported by tools available in ArcGIS™ software package. To estimate the infiltration potential (S and effective rainfall (Pe, as a function of rainfall duration equal to the maximum time of concentration of the water in the basin, Curve Number methodology proposed by the Natural Resources Conservation Service (NRCS was applied. Rainfall estimates were calculated using the maximum rain equation for the city of Belém, with return times specified at 2, 5, 10, 15, 20, 25, 50, 100, and 200 years. The results showed an increase in areas of high and medium population density (urban and reduced area of low population density (secondary forest growth for the years of 1972, 1977, 1998, and 2006, that generated a higher effective precipitation value and, therefore, a higher effective runoff coefficient value (C.

  15. Dos imaginários sobre a iniciação sexual: intersecções de gênero, raça/cor e sexualidade entre jovens de camadas populares em Belém, Pará

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    Ramon Reis

    Full Text Available Resumo Este texto propõe uma exposição sobre o “roteiro sexual” de mulheres e homens jovens (heterossexuais e homossexuais residentes em regiões “centrais” e “periféricas” da capital paraense, tendo como base material oriundo do projeto “‘Para entrar no mundo que não é meu’: a iniciação sexual a partir de entrevistas com as(os jovens pobres e de camadas médias de Belém do Pará”. Neste sentido, concentramos nossas incursões na Casa do Estudante Universitário do Pará (CEUP, localizada no bairro de classe média/média alta Batista Campos, e no bairro Guamá - “periferia” de Belém. Enfatizamos, assim, o importante papel das famílias de origem na reprodução de práticas de conduta social e sexual, além das distintas maneiras de as(os entrevistadas(os agenciarem suas iniciações sexuais a partir de convenções e imaginários acionados na interseção com gênero, sexualidade e raça/cor.

  16. Um altar romano na baía do Guajará: programa iconológico e reforma católica na Catedral da Sé de Belém do Pará (1867-1892

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    Aldrin Figueiredo

    2016-09-01

    Full Text Available Este artigo analisa o papel da arte sacra e religiosa na Amazônia no contexto do movimento de renovação do catolicismo brasileiro no século XIX, conhecido como reforma católica Para isso, toma, como objeto de análise, a encomenda do altar mor de Nossa Senhora de Belém pelo bispo do Pará D. Antônio de Macedo Costa (1830-1891 para o escultor e arquiteto italiano Luca Carimini (1830-1890. Essa obra, juntamente com outras realizadas no mesmo período do pontificado de Pio IX, perfaz um programa iconológico e um corpus narrativo de fundo artístico e sagrado, que são testemunhos da pedagogia e dos debates políticos na história do catolicismo romano e brasileiro do século XIX. Além disso, movimenta artistas que atuaram sob o mecenato do papa Pio IX para cidades latino-americanas como Santiago, no Chile, e Belém do Pará, no Brasil, evidenciando conexões artísticas, intelectuais e religiosas entre o Vaticano e a América do Sul, como parte do movimento internacional de renovação do catolicismo. 

  17. BEL β-trefoil: a novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms.

    Science.gov (United States)

    Bovi, Michele; Cenci, Lucia; Perduca, Massimiliano; Capaldi, Stefano; Carrizo, Maria E; Civiero, Laura; Chiarelli, Laurent R; Galliano, Monica; Monaco, Hugo L

    2013-05-01

    A novel lectin was purified from the fruiting bodies of king bolete mushrooms (Boletus edulis, also called porcino, cep or penny bun). The lectin was structurally characterized i.e its amino acid sequence and three-dimensional structure were determined. The new protein is a homodimer and each protomer folds as β-trefoil domain and therefore we propose the name Boletus edulis lectin (BEL) β-trefoil to distinguish it from the other lectin that has been described in these mushrooms. The lectin has potent anti-proliferative effects on human cancer cells, which confers to it an interesting therapeutic potential as an antineoplastic agent. Several crystal forms of the apoprotein and of complexes with different carbohydrates were studied by X-ray diffraction. The structure of the apoprotein was solved at 1.12 Å resolution. The interaction of the lectin with lactose, galactose, N-acetylgalactosamine and T-antigen disaccharide, Galβ1-3GalNAc, was examined in detail. All the three potential binding sites present in the β-trefoil fold are occupied in at least one crystal form and are described in detail in this paper. No important conformational changes are observed in the lectin when comparing its co-crystals with carbohydrates with those of the ligand-free protein.

  18. Human T-cell lymphotropic virus types I and II infections in a cohort of patients with neurological disorders in Belém, Pará, Brazil Infecção pelos vírus linfotrópicos humanos de células T tipos I e II entre pacientes com doença neurológica em Belém, Pará, Brasil

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    Olinda Macêdo

    2004-02-01

    Full Text Available Serum- and/or- cerebrospinal fluid (CSF samples obtained from 190 patients suffering from chronic, progressive neurological disease were screened for the presence of human T-cell lymphotropic viruses type I (HTLV-I and type II (HTLV-II antibodies over a six-year period (1996 to 2001 in Belém, Pará, Brazil. Patients were of both sexes (male subjects, 52% with ages ranging from 2 to 79 years (mean, 35.9. Overall, 15 (7.9% subjects - of whom 12 (80% were female adults - reacted HTLV-I/II-seropositive when screened by enzyme-linked immunosorbent assay (ELISA. Serum samples from 14 of these patients were also analyzed using a recombinant Western blot (WB assay that yielded HTLV-I-, HTLV-II-, and HTLV-I/II- reactivities for 10 (71.4%, 3 (21.4% and 1 (7.2% of them, respectively. The yearly rates of HTLV-I/II antibodies ranged from 2.6% (2001 to 21.7% (2000, with progressively increasing seropositivities from 1998 to 2000. Altogether, walking difficulty (n = 5 subjects, spasticity (n = 4 and leg weakness (n = 3 accounted for 80% of symptoms recorded among the 15 patients whose sera had antibodies to HTLV-I/II as detected by ELISA. These findings provide evidence that both HTLV-I and HTLV-II play a role in the development of chronic myelopathy in Belém, Pará, Northern Brazil.Amostras de soro e/ou líquido céfalo-raquidiano (LCR foram obtidas de 190 pacientes com quadro de doença neurológica crônica e progressiva, com vistas à detecção de anticorpos para os vírus linfotrópicos humanos de células T dos tipos I (HTLV-I e II (HTLV-II, durante um período de seis anos (1996 a 2001 em Belém, Pará, Brasil. O grupo compreendia ambos os sexos (homens, 52%, com idades variando de 2 a 79 anos (média, 35,9 anos. Tomando-se os resultados como um todo, 15 (7,9% indivíduos, incluindo 12 (80% mulheres adultas, apresentaram anticorpos para HTLV-I/II a partir da triagem pelo procedimento imunoenzimático (ELISA. Soros de 14 desses pacientes também foram

  19. “Un contexto para una masona, librepensadora, feminista y republicana: Belén de Sárraga (1872-1950”

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    Sylvia Hottinger Craig

    2013-01-01

    Full Text Available Belén de Sárraga (1893-1950 española, masona, republicana, librepensadora y feminista recorrió Latinoaméricade 1907 hasta 1931. Se fue de España llevándose unbagaje político adquirido en un período de republicanismotemprano. A través de las redes masónicas internacionales fue enlazando países donde propagar sus ideas.Implementó los orígenes del feminismo y del panamericanismo en Latinoamérica, el librepensamiento enIberoamérica ya tenía sus adeptos, muchos de ellostambién masones. Pero lo que parece haber pasadodesapercibido es que ella estaba-siguiendo las pautas propuestas por los participantes de sus afiliaciones. Sinembargo, en 1931 regresó a una España polarizada dentro de los marcos establecidos de los partidos políticosdurante su ausencia. Este trabajo pretende contextualizar a este personaje dentro de una época que nosha sidoobstruida por los acontecimientos que le siguieron.

  20. Estudo da conceituação e implementação de vias sanitárias em Belém: o caso da bacia de drenagem Estrada Nova

    OpenAIRE

    LIMA, Henrique Nazareno Santos

    2004-01-01

    Busca aperfeiçoar um conceito utilizado na engenharia sanitária aplicado a princípios de projetos de vias marginais de canais, pequenas vielas de dificil acesso e vias que conduzem coletores troncais do sistema de esgoto sanitário chamado de via sanitária. Utiliza um estudo de caso na cidade de Belém: a bacia da Estrada Nova, caracterizando seu funcionamento e relacionando-os com a situação urbanística dos bairros contidos no território da bacia, a partir da legislação de uso e controle da oc...

  1. Caratateua Island (Belém-PA: the occupation model nucleous and production forms of the space

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    Maria de Jesus Benjamin da Silva

    1998-12-01

    Full Text Available Este trabalho aborda a diversidade do processo de produção e reprodução do espaço urbano. A realidade analisada é a Ilha de Caratateua, que é parte integrante da Região Metropolitana de Belém. Nesta perspectiva, o processo de produção do espaço fundado nas relações de trabalho e através destas, nas relações entre o homem e a natureza, coloca-se com o urna relação que deve ser entendida em várias determinações: econômicas, políticas, ideológicas, sociais, culturais, jurídicas e filosóficas, que o integram . Em que medida estes fatores produzem na llha de Caratateua um espaço urbano com o condição e meio de reprodução da força do trabalho, é nossa preocupação fundamental de análise, a relação capital versus trabalho e também as relações sociais neste espaço urbano, verificando a complexidade existente através do crescimento urbano desordenado que produziu e reproduz o desequilíbrio no uso do solo urbano da Ilha

  2. Validação de indicadores do consumo de alimentos e bebidas obtidos por inquérito telefônico em Belém, Pará, Brasil Validation of food and beverage indicators obtained by telephone survey in Belém, Pará State, Brazil

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    Alice Cristina Medeiros das Neves

    2010-12-01

    Full Text Available O objetivo deste trabalho foi avaliar a validade relativa dos indicadores de consumo de alimentos e bebidas obtidos pelo sistema de vigilância por entrevista telefônica (VIGITEL. Foi avaliada uma amostra aleatória (n = 100 da amostra total de aproximadamente dois mil adultos, estudada pelo sistema, em 2009, em Belém, Pará, Brasil. Os indicadores avaliados foram fatores de proteção (consumo adequado de frutas, legumes e verduras e de risco (consumo de gordura saturada, refrigerante e bebidas alcoólicas para doenças crônicas não transmissíveis. Compararam-se os resultados obtidos a partir de entrevista telefônica e de três recordatórios de 24 horas (padrão de referência. O padrão de referência evidenciou subestimação na frequência dos indicadores, à exceção de refrigerantes e bebidas alcoólicas. As médias das frequências do consumo foram, em geral, maiores no grupo exposto (entrevistados pelo VIGITEL. Não se pode concluir que o VIGITEL não seja um bom indicador de consumo, pois o padrão de referência também apresenta limitações, portanto o uso daquele como instrumento de monitoramento é justificável.The aim of this study was to evaluate the relative validity of indicators of food and beverage intake obtained from the telephone interview surveillance system (VIGITEL. A random sample (n = 100 was evaluated from the total sample of approximately two thousand adults studied by the system in 2009 in Belém, Pará State, Brazil. The indicators were protective factors (adequate consumption of fruit, vegetables, and leafy vegetables and risk factors (consumption of saturated fat, soft drinks, and alcoholic beverages for chronic non-communicable diseases. The telephone interview results were compared with those of three 24-hour recalls (reference standard. The reference standard showed underestimation in the indicators' frequency, except for soft drinks and alcoholic beverages. The mean consumption frequencies were

  3. Formação pedagógica dos docentes do ensino superior: o ponto de vista de professores de uma universidade de Belém-Pará

    OpenAIRE

    Castro, Lilian Ruth Dias de

    2013-01-01

    A Formação Pedagógica dos Docentes do Ensino Superior: o ponto de vista dos professores de uma Universidade de Belém-Pará. O presente estudo aborda a Formação Pedagógica dos Docentes do Ensino Superior de uma universidade brasileira. Procuramos saber com dez professores, das 1.ª e 2.ª séries do curso de Licenciatura em Dança, as implicações que podem ocorrer no exercício da docência, com a falta da formação pedagógica necessária. As evidências que geraram as análises apresentadas nesta dis...

  4. RT-PCR for confirmation of echovirus 30 isolated in Belém, Brazil

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    Maria de Lourdes C. Gomes

    Full Text Available Echovirus (Echo 30 or human enterovirus B is the most frequent enterovirus associated with meningitis cases. Epidemics and outbreaks of this disease caused by Echo 30 have occurred in several countries. In Brazil, Echo 30 has been isolated from sporadic cases and outbreaks that occurred mainly in the south and southeast regions. We used RT-PCR to examine Echo 30 isolates from meningitis cases detected from March 2002 to December 2003 in Belém, state of Pará, in northern Brazil. The patients were attended in a Basic Health Unit (State Health Secretary of Pará, where cerebrospinal fluid (CSF was collected and stored in liquid nitrogen. Weekly visits were made by technicians from Evandro Chagas Institute to the health unit and samples were stored at -70ºC in the laboratory until use. HEp-2 and RD cell lines were used for viral isolation and neutralization with specific antisera for viral identification. RNA extraction was made using Trizol reagent. The RT-PCR was made in one step, and the total mixture (50 µL was composed of: RNA, reaction buffer, dNTP, primers, Rnase inhibitor, reverse transcriptase, Taq polymerase and water. The products were visualized in agarose gel stained with ethidium bromide, visualized under UV light. Among the 279 CSF samples examined, 30 (10.7% were EV positive, 29 being Echo 30 and one was Cox B. Nineteen Echo 30 were examined with RT-PCR; 18 tested positive (762 and 494 base pairs. The use of this technique permitted viral identification in less time than usual, which benefits the patient and is of importance for public-health interventions.

  5. Condições de saúde bucal de diabéticos acompanhados pelo Programa Saúde da Família em Belém - Pará

    OpenAIRE

    PINHEIRO, Helder Henrique Costa

    2006-01-01

    Neste estudo foram avaliadas as condições de saúde bucal de diabéticos acompanhados pelo Programa Saúde da Família no município de Belém-Pará. As condições analisadas foram: cárie dentária, doença periodontal, uso e necessidade de prótese dentária e lesões de mucosa. A amostra foi composta de 268 diabéticos e 270 indivíduos não diabéticos compondo o grupo controle. Para a coleta dos dados, foram utilizados os índices recomendados pela Organização Mundial de Saúde. Os exames foram realizados n...

  6. Festa de santo na cidade: notas sobre uma pesquisa etnográfica na periferia de Belém, Pará, Brasil

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    Antonio Maurício Dias da Costa

    Full Text Available O artigo faz alguns paralelos entre estudos que tratam da dimensão lúdica da religiosidade popular na Amazônia e os resultados de uma pesquisa etnográfica sobre uma festa de santo padroeiro em uma feira de bairro na Belém contemporânea. São observados elementos externos ao ritual religioso, como divulgação propagandística, trocas econômicas e usos políticos, que atuam como transformadores do sentido da devoção religiosa. Demonstra-se, com isso, a dinamicidade da reprodução da religiosidade popular, considerando a diversidade de manifestações festivas em diferentes realidades socioespaciais amazônicas. Devoção religiosa e 'razão prática' estão imbricadas no processo de modificação do evento pesquisado. Isto se revela pela complexidade das trocas sociais exercidas em uma festa de santo padroeiro na escala de uma grande cidade.

  7. Occurrence of strongyloidiasis among patients with HTLV-1/2 seen at the outpatient clinic of the Núcleo de Medicina Tropical, Belém, State of Pará, Brazil.

    Science.gov (United States)

    Furtado, Karen Cristini Yumi Ogawa; Costa, Carlos Araújo da; Ferreira, Louise de Souza Canto; Martins, Luisa Carício; Linhares, Alexandre da Costa; Ishikawa, Edna Aoba Yassui; Batista, Evander de Jesus Oliveira; Sousa, Maisa Silva de

    2013-01-01

    This study investigated the occurrence of Strongyloides stercoralis infestation and coinfection with HTLV-1/2 in Belém, Brazil. S. stercoralis was investigated in stool samples obtained from individuals infected with HTLV-1/2 and their uninfected relatives. The frequency of S. stercoralis was 9% (9/100), including six patients infected with HTLV-1 (14.3%), two patients infected with HTLV-2 (11.1%), and one uninfected relative. Two cases of hyperinfestation by S. stercoralis were characterized as HTLV-1. These results support the need for the routine investigation of S. stercoralis in patients with HTLV-1, in an attempt to prevent the development of severe forms of strongyloidiasis.

  8. Assessment of DDT and Metabolites in Soil and Sediment of Potentially Contaminated Areas of Belém, Amazon Region, Brazil.

    Science.gov (United States)

    Rodrigues, Andreia Oliveira; de Souza, Larissa Costa; da Silva Rocha, Cássia Christina; da Costa, Amilton Cesar Gomes; de Alcântara Mendes, Rosivaldo

    2017-07-01

    The aim of this study was to evaluate the distribution of DDT and metabolites in surface soils and soil profiles from two areas containing deposits of obsolete pesticides in Belém, Amazon Region, Brazil. DDT and metabolites were extracted by microwave assisted extraction and analyzed by gas chromatography with electron capture detection. Concentrations of total DDT in surface soil samples ranged from 64.22 mg kg -1 in area 1 (A1) to 447.84 mg kg -1 in area 2 (A2). Lower levels were found in soil profiles than at the surface (6.21-21.17 mg kg -1 in A1 and 36.13-113.66 mg kg -1 in A2). pp'-DDT, pp'-DDE and pp'-DDD were detected in sediments at levels of 2.01, 0.96 and 0.35 mg kg -1 , respectively. The ratio (DDE + DDD)/ΣDDT was low indicating the recent introduction of DDT to the environment in the two study areas, through the volatilization and atmospheric deposition of the obsolete pesticides.

  9. Vinte Anos da Convenção de Belém do Pará e a Lei Maria Da Penha

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    Lourdes Maria Bandeira

    2015-05-01

    Full Text Available Em 2014, completaram-se duas décadas da Convenção Interamericana para Prevenir, Punir e Erradicar a Violência Contra a Mulher (Convenção de Belém do Pará, que é a base original da Lei no 11.340 (Lei Maria da Penha e que continua a ser a referência para seu entendimento sociojurídico e a dimensionar sua eficácia. Nas comemorações destes 20 anos, vê-se maior precisão das compreensões e do desdobramento da Convenção, alcançados a partir das iniciativas tomadas pelos Estados signatários. Em um processo de retroalimentação, o refinamento de seus termos e princípios vem impactando legislações e medidas, adotados individualmente, dentro das soberanias nacionais. O presente artigo desenvolve uma reflexão sobre a Convenção e sua atual importância para o enfrentamento da violência contra as mulheres no Brasil, indicando perspectivas futuras ao escopo da Lei Maria da Penha.

  10. Interpretação dos Efeitos de Tempo Nublado e Chuvoso Sobre a Radiação Solar em Belém/PA Para Uso em Sistemas Fotovoltaicos

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    Mayara Soares Campos

    Full Text Available Resumo Neste trabalho foi desenvolvido um software que prediz a variação de direção de incidência dos raios solares ao longo do ano e dos horários do dia, o qual é utilizado para estimar a melhor orientação na instalação de painéis fotovoltaicos na cidade de Belém/PA. A utilização do potencial de radiação solar em Belém poderá ser transformada em energia útil. Todavia, a eficiência de conversão solar no local também depende das condições atmosféricas que interferem nesse aproveitamento. Portanto, também foram avaliados os efeitos de tempo nublado e chuvoso através da precipitação e da comparação entre a radiação simulada (para céu limpo e a radiação medida disponibilizada pelo INMET, que estima a radiação real, o que leva em conta efeitos que afetam a radiação, como céu nublado. Portanto, a partir da análise conjunta da radiação solar incidente na superfície com o índice pluviométrico, foi avaliada a potencialidade energética solar do local durante o ano, onde foi possível perceber uma correlação do período de menor precipitação com a elevação no índice de radiação medido, favorecendo nesse período um melhor rendimento energético para o painel fotovoltaico.

  11. Effect of Cement and Compaction on the Physicochemical Behavior of a Material in the Region of Sidi Bel Abbes

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    N. S. Ikhlef

    2014-08-01

    Full Text Available Soil treatment describes the procedure under which a soil acquires certain characteristics that did not originally have. This paper is focused in the field of road earthworks and the treatment of a material found in the region of Sidi Bel Abbes, Algeria. This material has poor characteristics that do not meet the standards used in road geotechnics. To remedy this, firstly, the Proctor Standard characteristics of this material were improved using mechanical treatment that increased the compaction energy. Then a chemical treatment was employed, adding some cement dosages, and results show that the material classified in the A1h class, for an increased maximum dry density and a reduction in water content. A comparative study is made on the optimal properties of the material between the two modes of treatment. On the other hand, after treatment, one finds a decrease in the plasticity index and the methylene blue value. This material exhibits a change of class. Therefore, soil class CL turned into a soil class CL-ML (silt of low plasticity. This observation allows the material to be used as backfill or subgrade.

  12. Associação entre hipertensão arterial e excesso de peso em adultos, Belém, Pará, 2005 Association between hyertension and overweight in adults in Belém, state of Pará (Brazil, 2005

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    Hilma Paixão Borges

    2008-08-01

    Full Text Available FUNDAMENTO: A hipertensão arterial constitui um grave problema de saúde pública, atingindo 20% a 25% da população adulta mundial e 12% a 35% da população brasileira. OBJETIVO: Avaliar associação entre hipertensão arterial e excesso de peso. MÉTODOS: Estudo transversal desenvolvido em 2005, com uma amostra probabilística da população >18 anos de Belém (PA, pelo SIMTEL (monitoramento de doenças crônicas por telefone. Considerou-se como variável desfecho: hipertensão; como variável explanatória: excesso de peso; como variáveis de confusão: idade, escolaridade e características de estilo de vida. As variáveis associadas com hipertensão arterial foram analisadas por regressão logística para cálculo de risco. RESULTADOS: A hipertensão arterial atingiu 16,2% dos homens e 18,3% das mulheres, e o excesso de peso, 49,3% e 34,0%, respectivamente. A prevalência de hipertensão arterial se associou diretamente com idade e com excesso de peso em ambos os sexos. Para os homens, se associou com consumo de frutas e hortaliças e baixo consumo de feijão; para as mulheres, com estado civil viúva ou separada e, inversamente, com escolaridade. O risco de hipertensão arterial aumentou com o peso em ambos os sexos (pBACKGROUND: Hypertension is a major public health issue affecting 20 to 25% of the global population of adults, and 12 to 35 % of Brazilians. OBJECTIVE: To evaluate the association between hypertension and overweight. METHODS: A cross-sectional study was conducted in 2005 with a probabilistic sampling of the population >18 years of age in Belém, capital of the state of Pará, in the Northern region of Brazil, using the telephone surveillance system for chronic diseases (SIMTEL. The dependent variable was hypertension, the explanatory variable was overweight and the confounding variables were age, level of education and lifestyle characteristics. The variables associated with hypertension were run through the regression

  13. Dentistry and food safety – the oral health of food handlers at a public hospital in the city of Belém, Pará

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    Elaine Beatriz Teixeira Ramalho

    2008-01-01

    Full Text Available Objective: This research evaluated the oral health of 40 food handlers in the Nutrition and Diet Unit of a public hospital in Belém-Pará. Methods: Interview and intra-oral examination of the subjects.Results: The results showed a high prevalence of tooth decay and periodontal disease, in addition to a low level of education and motivation as regards oral health care in the studied sample.Conclusion: The authors concluded that oral health care and education should be included in publications for and training of food handlers,since oral health promotion would benefit these workers directly, by increasing their quality of life, and indirectly benefit the entirecommunity that consumes the food prepared by them. The results and conclusions of this work should encourage the development of oralhealth care promotion programmers as regards this particular group of employees, the food handlers.

  14. Preliminary assessment of Miramar Petrochemical Harbor as PAH source to Guajará bay (Belém-PA-Brazil surface sediments

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    Silvana do Socorro Veloso Sodré

    Full Text Available Abstract A preliminary study on a petrochemical harbor as a potential source of polycyclic aromatic hydrocarbons (PAH to surface sediments of Guajará bay, located in Belém City, Pará State, Brazil, over the last 10 years is presented here. The 16 priority USEPA PAH were identified and quantified. Surface sediment samples, collected at 5 sites in the bay, near Miramar Petrochemical Harbor (TEMIR, were extracted and analyzed by high performance liquid chromatography with a diode array detector. Total PAH concentration ranged from 533.0 to 3123.3 ng g-1 dry weight with a mean concentration of 1091.9 ng g-1. The most contaminated places were those where muddy sediments were found with highest concentrations of organic matter. The priority PAH with low molecular weight represented 54.4% of the total abundance and indicate that the main source of contamination of the sediments was petrogenic, indicative of the relevant contribution of the petrochemical harbor activity to the input of PAH to Guajará bay. However, pyrolytic PAH coming from fuel combustion, household waste combustion and untreated sewage discharge are also potential contamination sources to this environment.

  15. Frequency of acute myeloid leukemia in children attended in Belém, Pará from August 2005 to May 2009

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    Lacy C. B. Junior

    2015-04-01

    Full Text Available Introduction: Acute myeloid leukemia (AML has variable incidence in different regions of Brazil. Objective: To determine the frequency of AML subtypes in children aged 0-17 years attended at Belém, Pará, from August 2005 to May 2009. Patients and methods: A retrospective study was performed with 278 patients diagnosed with acute or chronic leukemia based on clinical and morphological criteria (French-American-British [FAB]/World Health Organization classification [WHO] and immunophenotyping profile by flow cytometry, to determine the frequency of the subtypes in AML. Results: We found 70 (25.18% cases of AML, 37 of these (52.9% were children aged 0-17 years (median age of 7 years and 8 months. There was no statistical difference in relation to gender. We observed a higher frequency of AML subtype M2 (18/37 - 48.6% and M0/M1 (10/37 - 27%, especially in the first decade of life (16/28 [57.1%] AML M2 and 9/28 [32.1%] AML M0/M1. Conclusion: In the pediatric population, the types of AML M2, M0/M1 and M3 were respectively the most frequent.

  16. 45 CFR 98.90 - Monitoring.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Monitoring. 98.90 Section 98.90 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Monitoring, Non-compliance and Complaints § 98.90 Monitoring. (a) The Secretary will monitor programs funded under...

  17. Pintura rupestre esquemática sobre granito en la provincia de cáceres: los ejemplos de la Cueva Larga del Pradillo y Los Canchalejos de Belén (Trujillo

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    Hipólito COLLADO GIRALDO

    2010-08-01

    Full Text Available El análisis de las representaciones pertenecientes a dos estaciones con pinturas rupestres esquemáticas localizadas en el berrocal del término municipal de Trujillo (Cáceres, la Cueva Larga del Pradillo y Los Canchalejos de Belén, ambas conocidas de antiguo pero parcialmente publicadas –y una de ellas desaparecida en la actualidad–, dan pie a unas reflexiones sobre las características genéricas de este tipo de yacimientos rupestres en soporte granítico y sus representaciones pictóricas, sobre el estado de la investigación en torno al mismo en la Alta Extremadura, y sobre su encuadre cronológico y contexto sociocultural.

  18. Condições termodinâmicas de eventos de precipitação extrema em Belém-PA durante a estação chuvosa Thermodynamic conditions of extreme rainfall events in Belém-PA, Brazil, during the rainy season

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    João Paulo Nardin Tavares

    2012-07-01

    Full Text Available As condições termodinâmicas de uma região são muito importantes para o desenvolvimento da convecção úmida profunda, principalmente nas regiões tropicais. Portanto, o objetivo deste trabalho foi o de entender e caracterizar o papel das condições termodinâmicas da atmosfera durante os eventos de precipitações extremas na estação chuvosa, no período de 1987 a 2007, em Belém (PA. Os resultados mostram que as precipitações extremas, em sua maioria (56% apresentam um ambiente precursor com forte instabilidade, indicada pelos altos valores de CAPE (acima de 1000 J/kg e valores significativos dos índices de instabilidade. Houve, contudo, eventos com baixos valores de CAPE na sondagem das 1200 UTC do dia do evento, mas valores maiores na véspera, o que indica que a chuva em questão pode ter começado na madrugada e ter perdurado por várias horas, atravessando a hora da sondagem, explicando a queda deste parâmetro. Os índices de instabilidade K, TT e LI apresentaram uma boa representação do ambiente, prognosticando as tempestades com chuvas fortes com índice de acerto de até 74%, se levados em conta os eventos em que todos os índices apontavam os mesmos resultados e indicavam forte instabilidade. As condições termodinâmicas de forte instabilidade ajudam a promover, mas não são as únicas responsáveis pelas tempestades convectivas com precipitações extremas.The thermodynamic conditions from any region are very important to the development of the deep, moist convection, mainly in the tropical region. Therefore, the aim of this work was to understand and characterize the role of atmospheric thermodynamic conditions during extreme rainfall events in the rainy season, in Belém (PA, Brazil. The results show that the extreme rainfall, in their majority (56% present a pre-storm environment with strong instability, indicated by the CAPE high values (above 1000 J/kg and meaningful values of the instability indexes. There was

  19. Festa e espaço urbano: meios de sonorização e bailes dançantes na Belém dos anos 1950

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    Antonio Maurício Dias da Costa

    2012-01-01

    Full Text Available O artigo discute o uso de referências simbólicas de origem memorialística e jornalística atribuídas ao contexto socioespacial dos bailes dançantes de orquestras e sonoros em Belém, nos assim chamados 'clubes sociais' e 'clubes suburbanos'. As formas variadas de organização de festas dançantes na cidade estiveram associadas à difusão musical radiofônica nos anos 1950, mas também se ligaram à atuação dos sonoros comerciais ou daqueles especializados em bailes dançantes. Formas diferentes de uso e acesso aos meios de comunicação/sonorização pela população urbana foram acompanhadas pela ênfase da imprensa local na distinção social. Referências simbólicas e valorativas do espaço urbano emergem nos registros de jornal e memorialístico acerca do panorama festivo da cidade.

  20. Biologia da polinização da palmeira tucumã (Astrocaryum vulgare Mart. em Belém, Pará, Brasil Pollination biology of fiber palm (Astrocaryum vulgare Mart. in Belém, Pará, Brazil

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    Maria do Socorro Padilha de Oliveira

    2003-09-01

    Full Text Available Estudaram-se alguns aspectos da biologia da polinização da palmeira tucumã em uma área experimental da Embrapa Amazônia Oriental, em Belém, PA. Foram coletados dados de fenologia, morfologia floral, duração da floração, viabilidade polínica e visitantes florais em dez plantas, no período de janeiro a dezembro/1997. Trata-se de uma palmeira arbórea, multicaule, monóica, que possui inflorescência envolvida por uma bráctea lenhosa coberta por espinhos e centenas de flores unissexuais, sésseis. A flor feminina é ladeada por duas masculinas formando a tríade, localizando-se na base das ráquilas; creme e medindo de 5 a 10mm compr.; do tipo campanular, com pétalas aderidas ao estigma. As flores masculinas ocorrem em maior quantidade e medem de 2 a 4mm compr. Eventos de floração e de frutificação foram registrados em todo o período, com picos de março a julho e de dezembro a março, respectivamente. A abertura da bráctea e exposição da inflorescência ocorreu, principalmente, no início da manhã e da noite, períodos em que todas as flores femininas iniciam a antese, com o estigma apresentando secreção pegajosa, permanecendo receptivas por 24 a 36h. As flores masculinas também apresentaram antese simultânea e noturna, ficando viáveis por 24 a 36h, permanecendo aderidas às ráquilas por vários dias. A viabilidade polínica foi alta, tanto em botões em pré-antese como em flores abertas. As recompensas florais foram o pólen em abundância e a secreção estigmática. Várias partes da inflorescência, principalmente as flores, emitiram forte odor. Os visitantes florais foram insetos, com predominância de besouros e abelhas. Portanto, a palmeira tucumã é uma espécie protogínica, com pólen e forte odor como atrativos primários e polinização predominantemente cantarófila.It was studied some aspects of the pollination biology of fiber palm in experimental station of Embrapa, Eastern Amazon at Belém, PA

  1. Ocorrência de Campylobacter spp. em carne e miúdos de frango expostos ao consumo em Belém, Pará Occurence of Campylobacter spp. in chicken meat and giblets exposed to consumption in Northern Brazil

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    J.A. Freitas

    2007-06-01

    Full Text Available In order to study Campylobacter in chicken meat exposed to consumption in the city of Belém, state of Pará, Brazil, 16 samples (four of liver, four of gizzard, two of heart, two of skin, one of neck, two of carcass and a mixture of neck skin and fragments of the abdominal cavity, collected in clandestine butcher shops, fair-free and supermarkets were submitted to isolation and identification according to the recommended methods. In high percentage, the foods exposed to consumption were contaminated by this agent, meaning a potential risk to the human health.

  2. Usos e apropriações de multimídias na educação para a biodiversidade em escolas de Belém/PA

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    Lúcia das Graças Santana da Silva

    2016-07-01

    Full Text Available This research, carried out under the Capacity Institutional program through the Paraense Emilio Goeldi Museum/MCTI, identified perceptions about the concept of biodiversity in two school communities of elementary and high school in the city of Belém do Pará - Brazil, linked to municipal systems and state education, namely: Reference Center for Environmental Education Foundation Teacher Eidorfe Moreira and State Elementary School and Middle Vilhena Alves. Also identified as the Information and Communication Technologies and multimedia, act as mediators of the processes of teaching and learning about biodiversity in these communities. The methodology used is action research with participant observation (PERUZZO, 2003 and in-depth interviews of semi-open type with semi-structured questions (Duarte, 2009. It was concluded that the concept of biodiversity should be better worked in the school environment, in a structured way and with the pedagogical assistance of ICTs, whose educational use should be favored with the best investments in public education, especially in training and teachers' awareness of the pedagogical use ICT and multimedia.

  3. Branchial histopathological study of Brachyplatystoma rousseauxii (Castelnau, 1855 in the Guajará bay, Belém, Pará State, Brazil = Estudo histopatológico da brânquia de Brachyplatystoma rousseauxii na baía do Guajará, Belém, Estado do Pará, Brasil

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    Caroline da Silva Montes

    2010-01-01

    Full Text Available This work analyzes the morphological alterations in Brachyplatystoma rousseauxii gills and evaluates whether this species can be considered an environmental monitoring biomarker of Guajará Bay. Sampling was carried out in four areas around Belém, Brazil, in four annual periods: dry/wet season, wet season, wet/dry season and dry season. Water pH, temperature and suspended material were evaluated. A total of 36 specimens were collected. The second right gill arch of each animal was removed and immediately fixed and processed for histopathology analysis with light microscopy. The physicochemical analysis of the water during the study period showed slight acidity, temperature and material in suspension within normal levels. Histopathological analysis of the gills from 14 individuals from area I presented no alterations, and only 2 individuals from this area presented some significant type of alteration. In contrast, all individuals captured in areas II, III, and IV presented at least one of the following alterations: aneurism-like alterations, epithelial elevation, infiltration, cell proliferation and cell hypertrophy. Based on the gill histopathological analysis, this organ is considered a good biomarker and the native species B. rousseauxii could be used as a bioindicator for environmental monitoring.O objetivo deste trabalho foi analisar as alterações morfológicas branquiais em Brachyplatystoma rousseauxii e verificar se esta espécie pode ser considerada como indicador biológico para o monitoramento ambiental da baía do Guajará. As coletas aconteceram em quatro áreas ao redor da cidade de Belém: I (controle, II, III e IV (forte influência antrópica, nos quatro períodos anuais: estação seco/chuvoso, estação chuvoso, estação chuvoso/seco e estação seco. Nesses períodos foram medidos pH, temperatura e material em suspensão. Foram capturados 36 exemplares. O segundo arco branquial direito de cada animal foi retirado

  4. Restriction enzyme analysis of the human cytomegalovirus genome in specimens collected from immunodeficient patients in Belém, State of Pará, Brazil Análise de restrição enzimática do genoma viral do citomegalovírus humano em espécimes clínicos de pacientes imunodeficientes, Belém, Estado do Pará

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    Dorotéa Lobato da Silva

    2011-10-01

    Full Text Available INTRODUCTION: Human cytomegalovirus is an opportunistic betaherpesvirus that causes persistent and serious infections in immunodeficient patients. Recurrent infections occur due to the presence of the virus in a latent state in some cell types. It is possible to examine the virus using molecular methods to aid in the immunological diagnosis and to generate a molecular viral profile in immunodeficient patients. The objective of this study was to characterize cytomegalovirus genotypes and to generate the epidemiological and molecular viral profile in immunodeficient patients. METHODS: A total of 105 samples were collected from immunodeficient patients from the City of Belém, including newborns, hemodialysis patients, transplant recipients and HIV+ patients. An IgG and IgM antibody study was completed using ELISA, and enzymatic analysis by restriction fragment length polymorphism (RFLP was performed to characterize viral genotypes. RESULTS: It was observed that 100% of the patients had IgG antibodies, 87% of which were IgG+/IgM-, consistent with a prior infection profile, 13% were IgG+/IgM+, suggestive of recent infection. The newborn group had the highest frequency (27% of the IgG+/IgM+ profile. By RFLP analysis, only one genotype was observed, gB2, which corresponded to the standard AD169 strain. CONCLUSIONS: The presence of IgM antibodies in new borns indicates that HCMV continues to be an important cause of congenital infection. The low observed genotypic diversity could be attributed to the small sample size because newborns were excluded from the RFLP analysis. This study will be continued including samples from newborns to extend the knowledge of the general and molecular epidemiology of HCMV in immunodeficient patients.INTRODUÇÃO: O citomegalovírus é um betaherpesvírus oportunista, causador de infecções persistentes e graves em pacientes imunodeficientes. As infecções recorrentes ocorrem devido à presença do vírus em estado de

  5. "Brilham estrelas de São João!": notas sobre os concursos de "Miss Caipira Gay" e "Miss Caipira Mix" em Belém (PA

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    Rafael da Silva Noleto

    Full Text Available Este artigo é uma reflexão acerca dos concursos "Miss Caipira Gay" e "Miss Caipira Mix", promovidos, respectivamente, pela Prefeitura Municipal de Belém e pelo Governo do Estado do Pará por ocasião da realização dos festejos juninos na capital do estado do Pará. Com base em trabalho de campo realizado em 2012 e 2013, o texto busca problematizar aspectos relativos às ações dos poderes públicos locais no que diz respeito ao destaque dado ao protagonismo gay, travesti e transexual no contexto da programação das festas juninas realizadas por fundações culturais vinculadas aos poderes municipal e estadual. Assim, as reflexões aqui colocadas visam à compreensão da lógica própria utilizada nesses concursos de dança e beleza que opera a partir de uma articulação de conceitos vinculados aos marcadores sociais da diferença, tais como gênero, sexualidade, raça, classe, geração e etnicidade.

  6. O Secretário Executivo e a Tecnologia da Informação: Um Estudo Sobre A Utilização de Recursos Tecnológicos pelos Profissionais da Cidade de Belém/PA

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    Marco Antonio Lima

    2014-06-01

    Full Text Available Este estudo tem como objetivo analisar o grau de intensidade de utilização de aplicativos de Tecnologia da Informação (TI porprofissionais de Secretariado Executivo em organizações estabelecidas na cidadede Belém, no estado do Pará. Com a finalidade de sistematização da pesquisa, osaplicativos foram classificados em quatro diferentes categorias (Automação deEscritório, Comunicação, Gestão de Processos e Softwares Empresariais,baseados em uma adaptação do modelo de Turban, Mclean e Wetherbe (2004. Foirealizada aplicação de questionários a uma amostra não probabilística acidentalcomposta por 35 profissionais graduados do curso de Bacharelado em SecretariadoBilíngue e Trilíngue, residentes na cidade de Belém/PA. O modelo analítico foibaseado na análise estatística descritiva e análise cluster, obtendo comoprincipais resultados a identificação dos índices de utilização dos recursostecnológicos em escala coletiva e individual; e a classificação dos indivíduosem três agrupamentos com diferentes perfis de utilização dos recursos.Concluiu-se que os profissionais pesquisados utilizam os recursos tecnológicosdisponibilizados de forma desproporcional, concentrando-se na utilização deaplicativos para processamento de textos e para comunicação eletrônica,desperdiçando o potencial de ferramentas importantes como os aplicativos paragerenciamento de bancos de dados e gestão de projetos, que registrarambaixíssimos índices de utilização nesta pesquisa.

  7. Análise temporal da incidência da hepatite A no município de Belém-Pa, Brasil, nos anos de 2008 e 2009 e disseminação da informação na ilha de Cotijuba

    OpenAIRE

    Lena P. S. Rodrigues; Douglas Gasparetto; João J. B. Monteiro; Nelson F.L. Soffiatti; Nelson Veiga

    2015-01-01

    A análise de dados epidemiológicos, ambientais e sócio-econômicos foi modelada para reconhecer os fatores temáticos da Hepatite A e seus mecanismos de disseminação, na ilha de Cotijuba, onde os casos ocorridos em 2008 e 2009 foram indistintamente notificados em Belém - PA. Para reconhecer a existência desses fatores foram utilizadas geotecnologias emergentes associadas a estruturas de dados relacionais e não relacionais com o método de análise temporal da relação entre os fatores e a incidênc...

  8. Detection of HTLV-IIa in blood donors in an urban area of the Amazon Region of Brazil (Belém, PA

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    Ishak R.

    1998-01-01

    Full Text Available The human lymphotropic viruses type I (HTLV-I and type II (HTLV-II are members of a group of mammalian retroviruses with similar biological properties, and blood transfusion is an important route of transmission. HTLV-I is endemic in a number of different geographical areas and is associated with several clinical disorders. HTLV-II is endemic in several Indian groups of the Americas and intravenous drug abusers in North and South America, Europe and Southeast Asia. During the year of 1995, all blood donors tested positive to HTLV-I/II in the State Blood Bank (HEMOPA, were directed to a physician and to the Virus Laboratory at the Universidade Federal do Pará for counselling and laboratory diagnosis confirmation. Thirty-five sera were tested by an enzyme immune assay, and a Western blot that discriminates HTLV-I and HTLV-II infection. Two HTLV-II positive samples were submitted to PCR analysis of pX and env genomic region, and confirmed to be of subtype IIa. This is the first detection in Belém of the presence of HTLV-IIa infection among blood donors. This result emphasizes that HTLV-II is also present in urban areas of the Amazon region of Brazil and highlights the need to include screening tests that are capable to detect antibodies for both types of HTLV.

  9. El liderazgo del adulto mayor en la transformación de la subcultura de un grupo de adultos mayores del Centro Diurno para el Adulto Mayor de Belén por medio de la actividad física

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    Murillo Campos, Edgar

    2011-01-01

    Tesis texto completo Se analiza el impacto que tiene la participación de líderes adultos mayores en la modificación de la subcultura del Centro Diurno para el Adulto Mayor de Belén en relación con los estilos de vida saludable por medio de la actividad física. Participaron en el estudio 7 hombres entre los 65 y 91 años de edad y 29 mujeres entre los 65 y los 100 años de edad. Entre los instrumentos están: una entrevista en el campo del liderazgo aplicada a los dirigentes del Centro Diurno ...

  10. Res Dec 07 Final 05-12-07

    Indian Academy of Sciences (India)

    client1

    A tiyah (w inner of A bel prize for 2004, jointly w ith Isador Singer) says1 \\ A n y g o o d th eo rem should have severalproofs,m ore the better. For tw o reason s: u su ally, d i® eren t p ro ofs h ave d i® er- ent strengths and w eaknesses,and they general- ize in di® erent directions { they are not just rep- etitions ofeach other".

  11. Effects of atmospheric pressure cold plasma on human hepatocarcinoma cell and its 5-fluorouracil resistant cell line

    Energy Technology Data Exchange (ETDEWEB)

    Yang, H.; Gan, L.; Yang, X., E-mail: luxinpei@hotmail.com, E-mail: yangxl@mail.hust.edu.cn [College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074 (China); Lu, R. [School Hospital of Huazhong University of Science and Technology, Wuhan, Hubei 430074 (China); Xian, Y.; Lu, X., E-mail: luxinpei@hotmail.com, E-mail: yangxl@mail.hust.edu.cn [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074 (China)

    2015-12-15

    Atmospheric pressure cold plasma showed selective killing efficiency on cancer cells in vitro and in vivo, which makes plasma a potential option for cancer therapy. However, the plasma effects on chemotherapeutic drugs-resistant cells are rarely to be found. In this paper, the effects of plasma on human hepatocellular carcinoma Bel7402 cells and 5-fluorouracil (5-FU) resistant Bel7402/5FU cells were intensively investigated. The results showed that plasma induced superior toxicity to Bel7402 cells compared with Bel7402/5FU cells. Incubation with plasma-treated medium for 20 s induced more than 85% death rate in Bel7402 cells, while the same death ratio was achieved when Bel7402/5FU cells were treated for as long as 300 s. The hydrogen peroxide in the medium played a leading role in the cytotoxicity effects. Further studies implicated that when the treatment time was shorter than 60 s, the depolarization of mitochondrial membrane potential and apoptosis occurred through the intracellular reactive oxygen species accumulation in Bel7402 cells. Molecular analysis showed an increase in the transcription factor activity for AP-1, NF-kB, and p53 in Bel7402 cells. No obvious damage could be detected in plasma-treated Bel7402/5FU cells due to the strong intracellular reactive oxygen stress scavenger system.

  12. Effects of atmospheric pressure cold plasma on human hepatocarcinoma cell and its 5-fluorouracil resistant cell line

    Science.gov (United States)

    Yang, H.; Lu, R.; Xian, Y.; Gan, L.; Lu, X.; Yang, X.

    2015-12-01

    Atmospheric pressure cold plasma showed selective killing efficiency on cancer cells in vitro and in vivo, which makes plasma a potential option for cancer therapy. However, the plasma effects on chemotherapeutic drugs-resistant cells are rarely to be found. In this paper, the effects of plasma on human hepatocellular carcinoma Bel7402 cells and 5-fluorouracil (5-FU) resistant Bel7402/5FU cells were intensively investigated. The results showed that plasma induced superior toxicity to Bel7402 cells compared with Bel7402/5FU cells. Incubation with plasma-treated medium for 20 s induced more than 85% death rate in Bel7402 cells, while the same death ratio was achieved when Bel7402/5FU cells were treated for as long as 300 s. The hydrogen peroxide in the medium played a leading role in the cytotoxicity effects. Further studies implicated that when the treatment time was shorter than 60 s, the depolarization of mitochondrial membrane potential and apoptosis occurred through the intracellular reactive oxygen species accumulation in Bel7402 cells. Molecular analysis showed an increase in the transcription factor activity for AP-1, NF-кB, and p53 in Bel7402 cells. No obvious damage could be detected in plasma-treated Bel7402/5FU cells due to the strong intracellular reactive oxygen stress scavenger system.

  13. Evidence-Based Marketing for Academic Librarians

    OpenAIRE

    Yoo-Seong Song

    2006-01-01

    Objective - In developing marketing strategies for the Business & Economics Library (BEL) at the University of Illinois at Urbana-Champaign (UIUC), a survey was designed to answer the following questions: - Should BEL develop marketing strategies differently for East Asian business students? - What services do graduate business students want to receive from BEL? - With whom should BEL partner to increase visibility at the College of Business? Marketing research techniques were used to g...

  14. Perfil do desenvolvimento da linguagem de crianças no município de Belém, segundo o Teste de Triagem de Denver II

    Directory of Open Access Journals (Sweden)

    Elson Ferreira Costa

    2015-08-01

    Full Text Available Resumo:OBJETIVO:avaliar o desenvolvimento da linguagem, segundo o Teste de Triagem de Denver II, de crianças que frequentavam a educação infantil em Belém e verificar fatores associados do desfecho com as características familiares, ambientais e pessoais.MÉTODOS:trata-se de uma pesquisa transversal e de caráter descritivo exploratório. Foi aplicado um questionário aos genitores para coletar os dados pessoais, contextuais e familiares e um instrumento para medição do nível de pobreza familiar.RESULTADOS:das 319 crianças avaliadas, 59,2% apresentaram resultado suspeito de atraso na linguagem. As variáveis que mostraram associação estatisticamente significante com o nível de desenvolvimento da linguagem foram escolaridade paterna (p=0,003, idade materna (p=0,03 e o nível de pobreza urbana (p=0,003.CONCLUSÃO:destaca-se a importância de implementar programas de estimulação e monitoramento sistemático, além de alertar para a interferência negativa dos fatores de risco nesse processo.

  15. An Evaluation on Transfection Efficiency of pHRE-Egr1-EGFP in Hepatocellular Carcinoma Cells Bel-7402 Mediated by PEI-MZF-NPs

    Directory of Open Access Journals (Sweden)

    Mei Lin

    2011-01-01

    Full Text Available To improve transfection and expression efficiency of target gene, especially under cancer anoxic microenvironment, we have developed pHRE-Egr1-EGFP/PEI-MZF-NPs nanosystem, in which pHRE-Egr1-EGFP, eukaryotic gene expression plasmid, is constructed by combining radiation promoter Egr1 with anoxia induction components (HRE, forming anoxic radiation double sensitive HRE/Egr1 promoter to activate reporter gene EGFP expression. MZF-NPs (Mn0.5 Zn0.5 Fe2O4 magnetic nanoparticles, obtained by coprecipitation method, are coated with cation poly(ethylenimine (PEI. We transferred pHRE-Egr1-EGFP into hepatocellular carcinoma Bel-7402 cells, using PEI-MZF-NPs as the carrier and tested some relevant efficacy. The results show that PEI-MZF-NPs have good DNA-binding ability, protection ability, release ability, little toxicity, and high transfection efficiency, obviously superior to those of the liposome method and electricity perforation method. Moreover, the expression level of EGFP gene induced by anoxia and radiation was significantly higher than that of single radiation activation. It is therefore concluded that HRE/Egr1 can induce and improve target gene expression efficiency in cancer anoxic microenvironment, and that PEI-MZF-NPs can be used as a novel nonviral gene vector which offers a viable approach to the mediated radiation gene therapy of cancer.

  16. An Improved Brain-Inspired Emotional Learning Algorithm for Fast Classification

    Directory of Open Access Journals (Sweden)

    Ying Mei

    2017-06-01

    Full Text Available Classification is an important task of machine intelligence in the field of information. The artificial neural network (ANN is widely used for classification. However, the traditional ANN shows slow training speed, and it is hard to meet the real-time requirement for large-scale applications. In this paper, an improved brain-inspired emotional learning (BEL algorithm is proposed for fast classification. The BEL algorithm was put forward to mimic the high speed of the emotional learning mechanism in mammalian brain, which has the superior features of fast learning and low computational complexity. To improve the accuracy of BEL in classification, the genetic algorithm (GA is adopted for optimally tuning the weights and biases of amygdala and orbitofrontal cortex in the BEL neural network. The combinational algorithm named as GA-BEL has been tested on eight University of California at Irvine (UCI datasets and two well-known databases (Japanese Female Facial Expression, Cohn–Kanade. The comparisons of experiments indicate that the proposed GA-BEL is more accurate than the original BEL algorithm, and it is much faster than the traditional algorithm.

  17. Molecular analysis reveals the diversity of Hepatozoon species naturally infecting domestic dogs in a northern region of Brazil.

    Science.gov (United States)

    Gomes, Laise de Azevedo; Moraes, Pablo Henrique Gonçalves; do Nascimento, Luciana de Cássia Silva; O'Dwyer, Lucia Helena; Nunes, Márcio Roberto Teixeira; Rossi, Adriana Dos Reis Ponce; Aguiar, Délia Cristina Figueira; Gonçalves, Evonnildo Costa

    2016-10-01

    This study aimed to optimize molecular methods for detecting DNA of Hepatozoon spp. as well as identify the phylogenetic relationships of Hepatozoon strains naturally infecting domestic dogs in Belém, Pará, northern Brazil. Blood samples were collected from 138 dogs, and screened for Hepatozoon spp. using a new nested PCR assay. Positive samples were subjected to genetic characterization based on amplification and sequencing of approximately 670bp of the Hepatozoon spp. 18S rRNA. Of the positive dogs, four shared the haplotype Belém 01, one dog presented the haplotype Belém 02 and two dogs shared the haplotype Belém 03. A Bayesian inference indicates that haplotypes Belém 01 and Belém 02 are phylogenetically related to H. canis, while Belém 03 is related to H. americanum. Overall, based on the first molecular evidence of H. americanum in Brazilian domestic dogs, the proposed protocol may improve the epidemiological investigation of canine hepatozoonosis. Copyright © 2016 Elsevier GmbH. All rights reserved.

  18. Molecular cloning and genomic organization of a second probable allatostatin receptor from Drosophila melanogaster

    DEFF Research Database (Denmark)

    Lenz, C; Williamson, M; Grimmelikhuijzen, C J

    2000-01-01

    We (C. Lenz et al. (2000) Biochem. Biophys. Res. Commun. 269, 91-96) and others (N. Birgül et al. (1999) EMBO J. 18, 5892-5900) have recently cloned a Drosophila receptor that was structurally related to the mammalian galanin receptors, but turned out to be a receptor for a Drosophila peptide bel...

  19. Current structure and kinetic energy of the abyssal waters in the Central Indian Ocean Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Murty, V.S.N.; RameshBabu, V.; Suryanarayana, A.; Beena, B.S.

    of Bottom Ekman Layer (BEL) below 50 mab. Above BEL the total KE at each depth was dominated by eddy KE resulted from synoptic scale (12-15 day period) motions. In the BEL, the intertial and tidal oscillations contributed to the eddy KE. It is found...

  20. Bancroftian filariasis in Belém, Pará State: possibilities for eradication by introducing modern methods of control for Culex quinquefasciatus A filariose bancroftiana em Belém, Pará: possibilidades atuais de erradicação mediante a integração à campanha de novos métodos de controle da população de Culex quinquefasciatus

    Directory of Open Access Journals (Sweden)

    Habib Fraiha Neto

    1993-12-01

    Full Text Available For the past four decades, Belém has been considered to be the largest focus of Bancroftian filariasis in the Amazon region and one of the most important ones in Brazil. In 1952, practically one-fifth of the population was infected and it was estimated that there were 2,500 cases of Bancroftian elephantiasis. The major factor considered to be responsible for this situation was the high density of the main vector species: it was calculated that in April 1943 there was a mean of 67 infected mosquitoes per house. A control campaign was initiated in 1952, involving treatment of patients with diethylcarbamazine, as well as control of the vector. In 1956, vector control was discontinued because of a lack of efficient insecticides and financial limitations. Even so, the campaign was very successful and the incidence was reduced from 19.9% to 0.03%. Total eradication could be achieved if new methods of vector control were introduced, such as the use of Reiter's expanded polystyrene balls in cesspits and pit latrines, biological control using pathogenic bacteria, and improvement of basic sanitation.Há mais de quatro décadas Belém é considerada o maior foco de bancroftose da região amazônica e um dos mais importantes do Brasil. Em 1952, praticamente um quinto de sua população apresentava microfilárias no sangue, estimando-se em 2.500 os casos de elefantíase. O fator considerado o maior condicionante de tão extraordinária freqüência era a alta densidade local do principal vetor, Culex quinquefasciatus. Em abril de 1943 calculava-se uma média de 67 fêmeas da espécie infectadas por domicílio. Uma campanha de controle foi deflagrada em 1952, incluindo busca ativa e tratamento dos casos com dietilcarbamazina, além medidas de combate ao vetor. Estas foram abandonadas em 1956, por força da ineficácia ou do alto custo dos inseticidas. Ainda assim, a campanha foi muito bem sucedida, reduzindo a incidência de 19,9 para 0,03%. Hoje, a erradica

  1. Association between human parvovirus B19 and arthropathy in Belém, Pará, north Brazil Associação entre parvovírus B19 e artropatias em Belém, Pará, norte do Brasil

    Directory of Open Access Journals (Sweden)

    Ronaldo B. FREITAS

    2002-02-01

    Full Text Available A total of 220 patients with arthropathy were selected in Belém, Pará between January 1994 and December 2000, and screened for the presence of human parvovirus B19 IgM and IgG antibodies by enzyme-linked immunosorbent assay (ELISA. A subgroup (n = 132 of patients with high levels of antibodies (either IgM+/IgG+ or IgM-/IgG+ were examined for the presence of DNA by polymerase chain reaction/nested PCR. Recent/active infection (detection of IgM and/or IgG-specific antibodies and presence of viral DNA was identified in 47.7% of the 132 individuals with arthropathy. In our study, women were significantly more affected (59.7% than men (35.4% (P = 0.0006. The age group of 11-20 years (84.6%, among female patients, and 21-30 years (42.1%, among male, were those with the highest incidence rates. The analysis of the temporal distribution of B19-associated arthropaties showed a cyclic pattern, with peak incidence rates occuring at 3-5 year intervals. Significant diference (P = 0.01 was observed when comparing both the highest (39.0% and the lowest (11.0% seropositivity rates for the years of 1995 and 2000, respectively. The interfalangial joints of hands and feet were mostly affected, with 50.0% and 48.0% of cases among both women and men, respectively. In a smaller proportion, other joints such as those of knee, ankle, pulse and shoulder were affected. As for the duration, symptoms lasted 1 to 5 days in 54.0% of the individuals, whereas in 46.0% of them the disease lasted 6-10 days, if considered the subgroup (n = 63 of patients with recent/active infection by parvovirus B19. In our study, joint clinical manifestations occurred symmetrically. Our results indicate that B19 may be an important agent of arthropathies in our region, and this underscores the need for specific laboratory diagnosis when treating patients suffering from acute arthropathy, mainly pregnant women.Um total de 220 indivíduos portadores de artropatias foi selecionado em Belém, Par

  2. Norovirus diversity in diarrheic children from an African-descendant settlement in Belém, Northern Brazil.

    Directory of Open Access Journals (Sweden)

    Glicélia Cruz Aragão

    Full Text Available Norovirus (NoV, sapovirus (SaV and human astrovirus (HAstV are viral pathogens that are associated with outbreaks and sporadic cases of gastroenteritis. However, little is known about the occurrence of these pathogens in relatively isolated communities, such as the remnants of African-descendant villages ("Quilombola". The objective of this study was the frequency determination of these viruses in children under 10 years, with and without gastroenteritis, from a "Quilombola" Community, Northern Brazil. A total of 159 stool samples were obtained from April/2008 to July/2010 and tested by an enzyme immunoassay (EIA and reverse transcription-polymerase chain reaction (RT-PCR to detect NoV, SaV and HAstV, and further molecular characterization was performed. These viruses were detected only in the diarrheic group. NoV was the most frequent viral agent detected (19.7%-16/81, followed by SaV (2.5%-2/81 and HAstV (1.2%-1/81. Of the 16 NoV-positive samples, 14 were sequenced with primers targeting the B region of the polymerase (ORF1 and the D region of the capsid (ORF2. The results showed a broad genetic diversity of NoV, with 12 strains being classified as GII-4 (5-41.7%, GII-6 (3-25%, GII-7 (2-16.7%, GII-17 (1-8.3% and GI-2 (1-8.3%, as based on the polymerase region; 12 samples were classified, based on the capsid region, as GII-4 (6-50%, being 3-2006b variant and 3-2010 variant, GII-6 (3-25%, GII-17 (2-16.7% and GII-20 (1-8.3%. One NoV-strain showed dual genotype specificity, based on the polymerase and capsid region (GII-7/GII-20. This study provides, for the first time, epidemiological and molecular information on the circulation of NoV, SaV and HAstV in African-descendant communities in Northern Brazil and identifies NoV genotypes that were different from those detected previously in studies conducted in the urban area of Belém. It remains to be determined why a broader NoV diversity was observed in such a semi-isolated community.

  3. Klaasist kodu / Ivi Piho

    Index Scriptorium Estoniae

    Piho, Ivi, 1959-

    2003-01-01

    Klaasikunstniku Agnes Tormi ja Mati Tormi perekonna uus kodu. 145 mø eramu projekteeris arhitekt Heiki Teras. Mööbel valiti IKEA kataloogidest, köögimööbel telliti Eesti firmalt Loo Mööbel, klaasist detailid on valmistatud Disainklaasis. Klaasist on kappide uksed, lauaplaadid, dushikabiin, vannitoa uks jm. 13 ill

  4. Branchial histopathological study of Brachyplatystoma rousseauxii (Castelnau, 1855 in the Guajará bay, Belém, Pará State, Brazil - DOI: 10.4025/actascibiolsci.v32i1.4800

    Directory of Open Access Journals (Sweden)

    Rossineide Martins Rocha

    2009-12-01

    Full Text Available This work analyzes the morphological alterations in Brachyplatystoma rousseauxii gills and evaluates whether this species can be considered an environmental monitoring biomarker of Guajará Bay. Sampling was carried out in four areas around Belém, Brazil, in four annual periods: dry/wet season, wet season, wet/dry season and dry season. Water pH, temperature and suspended material were evaluated. A total of 36 specimens were collected. The second right gill arch of each animal was removed and immediately fixed and processed for histopathology analysis with light microscopy. The physicochemical analysis of the water during the study period showed slight acidity, temperature and material in suspension within normal levels. Histopathological analysis of the gills from 14 individuals from area I presented no alterations, and only 2 individuals from this area presented some significant type of alteration. In contrast, all individuals captured in areas II, III, and IV presented at least one of the following alterations: aneurism-like alterations, epithelial elevation, infiltration, cell proliferation and cell hypertrophy. Based on the gill histopathological analysis, this organ is considered a good biomarker and the native species B. rousseauxii could be used as a bioindicator for environmental monitoring.

  5. An optical laser device for mapping 3D geometry of underwater karst structures: first tests in the Ox BelHa system, Yucatan, Mexico; Un dispositivo laser optico para la cartografia 3D de la geometria de estructuras karsticas submarinas: primeros resultados en el sistema de Ox BelHa, Yucatan, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Schiller, A.; Renard, P.

    2016-07-01

    In the course of extended hydrological studies in the coastal Karst plain of Yucatan, near the town of Tulum amongst others, a novel laser scanning device was developed and applied for the acquisition of the 3d-geometry of ground water conduits. The method is derived from similar industrial systems and for the first time adapted to the specific measurement conditions in underwater cave systems. The device projects a laser line over the whole perimeter at a certain position. This line represents the intersection of a plane with the cave walls. The line is imaged with a wide angle camera system. Through proper design and calibration of the device it is possible to derive the true scale geometry of the perimeter via special image processing techniques. By acquiring regularly spaced images it is possible to reconstruct the true scale and 3 d-shape of a tunnel through the incorporation of location and attitude data. In a first test in the Ox Bel Ha under-water cave system, about 800 metres of tunnels have been scanned down to water depths of 20 metres. The raw data is further interpolated using the ODSIM-algorithm in order to delineate the 3D geometry of the cave system. The method provides easy, operable acquisition of the 3-D geometry of caves in clear water with superior resolution and speed and significantly facilitates the measurement in underwater tunnels as well as in dry tunnels. The data gathered represents crucial input to the study of the state, dynamics and genesis of the complex karst water regime. (Author)

  6. Usos e apropriações de multimídias na educação para a biodiversidade em escolas de Belém/PA

    Directory of Open Access Journals (Sweden)

    Mayara Santos Maciel

    2016-01-01

    Full Text Available Esta pesquisa, realizada no âmbito do Programa de Capacitação Institucional através do Museu Paraense Emilio Goeldi/MCTI, identificou as percepções sobre o conceito de biodiversidade em duas comunidades escolares de Ensino Fundamental e Médio da cidade de Belém do Pará - Brasil, vinculadas aos sistemas municipal e estadual de ensino, a saber: Fundação Centro de Referência em Educação Ambiental Professor Eidorfe Moreira e Escola Estadual de Ensino Fundamental e Médio Vilhena Alves. Também identificou como as Tecnologias da Informação e da Comunicação e multimídias atuam como mediadoras dos processos de ensino e aprendizado sobre biodiversidade nestas comunidades. Como metodologia foi utilizada a pesquisa-ação com observação participante (PERUZZO, 2003 e entrevistas em profundidade do tipo semi-abertas com questões semi-estruturadas (Duarte, 2009. Concluiu-se que o conceito de biodiversidade deve ser melhor trabalhado em âmbito escolar, de uma forma estruturada e com o auxílio pedagógico das TICs, cujo uso educativo deve ser favorecido com melhores investimentos na educação pública, principalmente na formação e sensibilização de professores para o uso pedagógico das TICs e multimídias.

  7. Variáveis relacionadas à iniciação do tabagismo entre estudantes do ensino médio de escola pública e particular na cidade de Belém - PA Variables related to smoking initiation among students in public and private high schools in the city of Belém, Brazil

    Directory of Open Access Journals (Sweden)

    Denise da Silva Pinto

    2007-10-01

    Full Text Available OBJETIVO: Analisar as variáveis relacionadas à iniciação do tabagismo entre adolescentes estudantes de nível médio de uma escola particular e outra pública, na cidade de Belém-PA, em 2005. MÉTODOS: Para a coleta de dados, foi utilizado um questionário não identificado, de autopreenchimento, com 27 questões fechadas, sobre experimentação de cigarro, fumo habitual, acesso à compra de cigarros, motivo para a experimentação do fumo, autopercepção sobre o seu rendimento escolar, diálogo sobre tabagismo no ambiente familiar e nível sócio-econômico. Participaram do estudo 1520 estudantes, sendo 724 (47,6% da rede particular e 796 (52,4% da rede pública. RESULTADOS: A média de idade dos estudantes foi de 16,5 anos. Dos 1520 estudantes, 669 (44% referiram ter experimentado cigarro e 11% faziam uso habitual de cigarros. A proporção de experimentadores na escola pública foi de 51,2% e na particular foi de 36,7% (p = 0; a de fumantes habituais foi 14,6% na escola pública e de 7% na particular (p = 0. As associações encontradas para iniciação e uso atual de cigarro em ambas as escolas foram: curiosidade, presença de pessoas fumantes no convívio social do adolescente, não ter sido elogiado por não fumar, e se considerar um aluno regular ou ruim. Não houve associação entre experimentação e fumo atual com classes sociais nas duas escolas, exceto para experimentadores das classes A e B na escola particular. CONCLUSÕES: A variável mais importante para fumo entre os estudantes foi a curiosidade. A experimentação e uso habitual de cigarro foram mais freqüentes na escola pública que na particular.OBJETIVE: To analyze the variables related to smoking initiation among adolescent students in two high schools (one public and one private in the city of Belém, Brazil, in 2005. METHODS: An anonymous self-report questionnaire - comprising 27 closed questions regarding smoking experimentation, smoking habit, access to buying

  8. UNOBSCURED TYPE 2 ACTIVE GALACTIC NUCLEI

    International Nuclear Information System (INIS)

    Shi, Yong; Rieke, George H.; Smith, Paul; Donley, Jennifer; Schmidt, Gary; Diamond-Stanic, Aleksandar M.; Rigby, Jane; Hines, Dean

    2010-01-01

    Type 2 active galactic nuclei (AGNs) with intrinsically weak broad emission lines (BELs) would be exceptions to the unified model. After examining a number of proposed candidates critically, we find that the sample is contaminated significantly by objects with BELs of strengths indicating that they actually contain intermediate-type AGNs, plus a few Compton-thick sources as revealed by extremely low ratios of X-ray to nuclear IR luminosities. We develop quantitative metrics that show two (NGC 3147 and NGC 4594) of the remaining candidates to have BELs 2-3 orders of magnitude weaker than those of typical type 1 AGNs. Several more galaxies remain as candidates to have anomalously weak BELs, but this status cannot be confirmed with the existing information. Although the parent sample is poorly defined, the two confirmed objects are well under 1% of its total number of members, showing that the absence of a BEL is possible, but very uncommon in AGN. We evaluate these two objects in detail using multi-wavelength measurements including new IR data obtained with Spitzer and ground-based optical spectropolarimeteric observations. They have little X-ray extinction with N H 21 cm -2 . Their IR spectra show strong silicate emission (NGC 4594) or weak aromatic features on a generally power-law continuum with a suggestion of silicates in emission (NGC 3147). No polarized BEL is detected in NGC 3147. These results indicate that the two unobscured type 2 objects have circumnuclear tori that are approximately face-on. Combined with their X-ray and optical/UV properties, this behavior implies that we have an unobscured view of the nuclei and thus that they have intrinsically weak BELs. We compare their properties with those of the other less-extreme candidates. We then compare the distributions of bolometric luminosities and accretion rates of these objects with theoretical models that predict weak BELs.

  9. BioCreative V track 4: a shared task for the extraction of causal network information using the Biological Expression Language.

    Science.gov (United States)

    Rinaldi, Fabio; Ellendorff, Tilia Renate; Madan, Sumit; Clematide, Simon; van der Lek, Adrian; Mevissen, Theo; Fluck, Juliane

    2016-01-01

    Automatic extraction of biological network information is one of the most desired and most complex tasks in biological and medical text mining. Track 4 at BioCreative V attempts to approach this complexity using fragments of large-scale manually curated biological networks, represented in Biological Expression Language (BEL), as training and test data. BEL is an advanced knowledge representation format which has been designed to be both human readable and machine processable. The specific goal of track 4 was to evaluate text mining systems capable of automatically constructing BEL statements from given evidence text, and of retrieving evidence text for given BEL statements. Given the complexity of the task, we designed an evaluation methodology which gives credit to partially correct statements. We identified various levels of information expressed by BEL statements, such as entities, functions, relations, and introduced an evaluation framework which rewards systems capable of delivering useful BEL fragments at each of these levels. The aim of this evaluation method is to help identify the characteristics of the systems which, if combined, would be most useful for achieving the overall goal of automatically constructing causal biological networks from text. © The Author(s) 2016. Published by Oxford University Press.

  10. Sorafenib modulates the radio sensitivity of hepatocellular carcinoma cells in vitro in a schedule-dependent manner

    International Nuclear Information System (INIS)

    Li, Qiaoqiao; Hu, Yonghong; Xi, Mian; He, Liru; Zhao, Lei; Liu, Mengzhong

    2012-01-01

    Hepatocellular carcinoma (HCC) has a high incidence and mortality. Radiotherapy and sorafenib have proven effective for HCC. Here, we investigated whether sorafenib modulated the response of HCC cells to irradiation in vitro, effect of timing of sorafenib, and the underlying mechanisms. Cell viability of the HCC cell lines, SMMC-7721 and Bel-7402, was examined by the 3-(4,5-dimethylthiazol-2-yl)-5(3-carboxymethoxyphenyl)-2(4-sulfophenyl)-2 H-terazolium (MTT) assays. Clonogenic growth assays of SMMC-7721 and Bel-7402 were determined by colony formation assays. DNA damage was assessed by monitoring γ-HAX foci in irradiated cells with immunofluorescence microscopy, and cell cycle distribution changes were examined by flow cytometry. Effects of sorafenib (15 μM) added 30 min prior to radiation (pre-irradiation sorafenib) of SMMC-7721 and BEL-7402 or 24 h post-irradiation (post-irradiation sorafenib) on irradiated SMMC-7721 and BEL-7402 cells were compared to those of radiation alone or no treatment. The effect of sorafenib was dependent on its time of addition in relationship to irradiation of cells. Pre-irradiation sorafenib did not significantly affect the viability of SMMC-7221 and BEL-7402 cells compared with irradiation treatment alone. In contrast, post-irradiation sorafenib increased the sensitivity of irradiated SMMC-7221 and BEL-7402 cells significantly in a time-dependent manner. Pre-irradiation sorafenib significantly increased the surviving fraction of SMMC-7221 and BEL-7402 cells in clonogenic assays whereas post-irradiation sorafenib significantly reduced the surviving fractions of SMMC-7221 and BEL-7402 cells. SMMC-7721 cells treated with sorafenib 30 min before irradiation had significantly fewer cells with γ-H2AX foci (23.8 ± 2.9%) than SMMC-7721 cells receiving radiation alone (59.9 ± 2.4; P < 0.001). Similarly, BEL-7402 cells receiving sorafenib prior to irradiation had significantly fewer cells with γ-H2AX foci (46.4 ± 3.8%) than those

  11. Cosmology with equivalence principle breaking in the dark sector

    International Nuclear Information System (INIS)

    Keselman, Jose Ariel; Nusser, Adi; Peebles, P. J. E.

    2010-01-01

    A long-range force acting only between nonbaryonic particles would be associated with a large violation of the weak equivalence principle. We explore cosmological consequences of this idea, which we label ReBEL (daRk Breaking Equivalence principLe). A high resolution hydrodynamical simulation of the distributions of baryons and dark matter confirms our previous findings that a ReBEL force of comparable strength to gravity on comoving scales of about 1 h -1 Mpc causes voids between the concentrations of large galaxies to be more nearly empty, suppresses accretion of intergalactic matter onto galaxies at low redshift, and produces an early generation of dense dark-matter halos. A preliminary analysis indicates the ReBEL scenario is consistent with the one-dimensional power spectrum of the Lyman-Alpha forest and the three-dimensional galaxy autocorrelation function. Segregation of baryons and DM in galaxies and systems of galaxies is a strong prediction of ReBEL. ReBEL naturally correlates the baryon mass fraction in groups and clusters of galaxies with the system mass, in agreement with recent measurements.

  12. Restriction enzyme analysis of the human cytomegalovirus genome in specimens collected from immunodeficient patients in Belém, State of Pará, Brazil

    Directory of Open Access Journals (Sweden)

    Dorotéa Lobato da Silva

    2011-10-01

    Full Text Available INTRODUCTION: Human cytomegalovirus is an opportunistic betaherpesvirus that causes persistent and serious infections in immunodeficient patients. Recurrent infections occur due to the presence of the virus in a latent state in some cell types. It is possible to examine the virus using molecular methods to aid in the immunological diagnosis and to generate a molecular viral profile in immunodeficient patients. The objective of this study was to characterize cytomegalovirus genotypes and to generate the epidemiological and molecular viral profile in immunodeficient patients. METHODS: A total of 105 samples were collected from immunodeficient patients from the City of Belém, including newborns, hemodialysis patients, transplant recipients and HIV+ patients. An IgG and IgM antibody study was completed using ELISA, and enzymatic analysis by restriction fragment length polymorphism (RFLP was performed to characterize viral genotypes. RESULTS: It was observed that 100% of the patients had IgG antibodies, 87% of which were IgG+/IgM-, consistent with a prior infection profile, 13% were IgG+/IgM+, suggestive of recent infection. The newborn group had the highest frequency (27% of the IgG+/IgM+ profile. By RFLP analysis, only one genotype was observed, gB2, which corresponded to the standard AD169 strain. CONCLUSIONS: The presence of IgM antibodies in new borns indicates that HCMV continues to be an important cause of congenital infection. The low observed genotypic diversity could be attributed to the small sample size because newborns were excluded from the RFLP analysis. This study will be continued including samples from newborns to extend the knowledge of the general and molecular epidemiology of HCMV in immunodeficient patients.

  13. Dynamical laws of superenergy in general relativity

    International Nuclear Information System (INIS)

    Gomez-Lobo, Alfonso GarcIa-Parrado

    2008-01-01

    The Bel and Bel-Robinson tensors were introduced nearly 50 years ago in an attempt to generalize to gravitation the energy-momentum tensor of electromagnetism. This generalization was successful from the mathematical point of view because these tensors share mathematical properties which are remarkably similar to those of the energy-momentum tensor of electromagnetism. However, the physical role of these tensors in general relativity has remained obscure and no interpretation has achieved wide acceptance. In principle, they cannot represent energy and the term superenergy has been coined for the hypothetical physical magnitude lying behind them. In this work, we try to shed light on the true physical meaning of superenergy by following the same procedure which enables us to give an interpretation of the electromagnetic energy. This procedure consists in performing an orthogonal splitting of the Bel and Bel-Robinson tensors and analyzing the different parts resulting from the splitting. In the electromagnetic case such splitting gives rise to the electromagnetic energy density, the Poynting vector and the electromagnetic stress tensor, each of them having a precise physical interpretation which is deduced from the dynamical laws of electromagnetism (Poynting theorem). The full orthogonal splitting of the Bel and Bel-Robinson tensors is more complex but, as expected, similarities with electromagnetism are present. Also the covariant divergence of the Bel tensor is analogous to the covariant divergence of the electromagnetic energy-momentum tensor and the orthogonal splitting of the former is found. The ensuing equations are to the superenergy what the Poynting theorem is to electromagnetism. Some consequences of these dynamical laws of superenergy are explored, among them the possibility of defining superenergy radiative states for the gravitational field

  14. Karyopathological traits of thyrocytes and exposure to radioiodines in Belarusian children and adolescents following the accident at the Chernobyl nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Nadyrov, Eldar; Rozhko, Alexander; Nikonovich, Sergey [Republican Research Center for Radiation Medicine and Human Ecology, Gomel (Belarus); Kravtsov, Viacheslav; Aleksanin, Sergey [EMERCOM of Russia, Nikiforov Russian Centre of Emergency and Radiation Medicine, St. Petersburg (Russian Federation); Mabuchi, Kiyohiko; Hatch, Maureen [National Cancer Institute, Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Rockville, MD (United States); Nakamura, Nori [Radiation Effects Research Foundation, Hiroshima (Japan)

    2012-05-15

    The Belarus-American (BelAm) thyroid study cohort consists of persons who were 0-18 years of age at the time of exposure to radioactive iodine fallout from the 1986 Chernobyl nuclear power plant accident and who have undergone serial thyroid screenings with referral for fine-needle aspiration biopsy (FNAB) using standardized criteria. We investigated thyrocyte nuclear abnormalities in cytological samples from FNABs in 75 BelAm subjects with single and multiple thyroid nodules and 47 nodular goiter patients from Leningrad, Russia, unexposed to Chernobyl fallout. Nuclear abnormalities examined included internuclear chromosome bridges and derivative nuclei with broken bridges (i.e., ''tailed'' nuclei), which are formed from dicentric and ring chromosomes and thus may be cellular markers of radiation exposure. Among subjects with single-nodular goiter, thyrocytes with bridges were present in 86.8% of the exposed BelAm cohort compared with 27.0% of unexposed controls. The average frequency of thyrocytes with bridges and with tailed nuclei was also significantly higher in the BelAm subjects than in controls. Among subjects with multinodular goiters, thyrocytes with bridges were present in 75.7% of exposed BelAm patients compared with 16.7% of unexposed controls; thyrocytes with tailed nuclei were observed in all of the BelAm subjects but in only 40% of controls, and the mean frequencies of bridges and tailed nuclei were significantly higher in the exposed group. Unusually, long bridges were detected in 29% of BelAm patients with single-nodular goiters and 35% of those with multinodular goiters, while no such abnormalities were observed among patients from the Leningrad region. In the exposed subjects from BelAm, we also found positive correlations between their estimated dose of Iodine-131 from Chernobyl fallout and the frequency of tailed nuclei (p = 0.008) and bridges (p = 0.09). Further study is needed to confirm that these phenomena represent

  15. Karyopathological traits of thyrocytes and exposure to radioiodines in Belarusian children and adolescents following the accident at the Chernobyl nuclear power plant

    International Nuclear Information System (INIS)

    Nadyrov, Eldar; Rozhko, Alexander; Nikonovich, Sergey; Kravtsov, Viacheslav; Aleksanin, Sergey; Mabuchi, Kiyohiko; Hatch, Maureen; Nakamura, Nori

    2012-01-01

    The Belarus-American (BelAm) thyroid study cohort consists of persons who were 0-18 years of age at the time of exposure to radioactive iodine fallout from the 1986 Chernobyl nuclear power plant accident and who have undergone serial thyroid screenings with referral for fine-needle aspiration biopsy (FNAB) using standardized criteria. We investigated thyrocyte nuclear abnormalities in cytological samples from FNABs in 75 BelAm subjects with single and multiple thyroid nodules and 47 nodular goiter patients from Leningrad, Russia, unexposed to Chernobyl fallout. Nuclear abnormalities examined included internuclear chromosome bridges and derivative nuclei with broken bridges (i.e., ''tailed'' nuclei), which are formed from dicentric and ring chromosomes and thus may be cellular markers of radiation exposure. Among subjects with single-nodular goiter, thyrocytes with bridges were present in 86.8% of the exposed BelAm cohort compared with 27.0% of unexposed controls. The average frequency of thyrocytes with bridges and with tailed nuclei was also significantly higher in the BelAm subjects than in controls. Among subjects with multinodular goiters, thyrocytes with bridges were present in 75.7% of exposed BelAm patients compared with 16.7% of unexposed controls; thyrocytes with tailed nuclei were observed in all of the BelAm subjects but in only 40% of controls, and the mean frequencies of bridges and tailed nuclei were significantly higher in the exposed group. Unusually, long bridges were detected in 29% of BelAm patients with single-nodular goiters and 35% of those with multinodular goiters, while no such abnormalities were observed among patients from the Leningrad region. In the exposed subjects from BelAm, we also found positive correlations between their estimated dose of Iodine-131 from Chernobyl fallout and the frequency of tailed nuclei (p = 0.008) and bridges (p = 0.09). Further study is needed to confirm that these phenomena represent consequences of

  16. Sorafenib modulates the radio sensitivity of hepatocellular carcinoma cells in vitro in a schedule-dependent manner

    Directory of Open Access Journals (Sweden)

    Li Qiaoqiao

    2012-10-01

    Full Text Available Abstract Background Hepatocellular carcinoma (HCC has a high incidence and mortality. Radiotherapy and sorafenib have proven effective for HCC. Here, we investigated whether sorafenib modulated the response of HCC cells to irradiation in vitro, effect of timing of sorafenib, and the underlying mechanisms. Methods Cell viability of the HCC cell lines, SMMC-7721 and Bel-7402, was examined by the 3-(4,5-dimethylthiazol-2-yl-5(3-carboxymethoxyphenyl-2(4-sulfophenyl-2 H-terazolium (MTT assays. Clonogenic growth assays of SMMC-7721 and Bel-7402 were determined by colony formation assays. DNA damage was assessed by monitoring γ-HAX foci in irradiated cells with immunofluorescence microscopy, and cell cycle distribution changes were examined by flow cytometry. Effects of sorafenib (15 μM added 30 min prior to radiation (pre-irradiation sorafenib of SMMC-7721 and BEL-7402 or 24 h post-irradiation (post-irradiation sorafenib on irradiated SMMC-7721 and BEL-7402 cells were compared to those of radiation alone or no treatment. Results The effect of sorafenib was dependent on its time of addition in relationship to irradiation of cells. Pre-irradiation sorafenib did not significantly affect the viability of SMMC-7221 and BEL-7402 cells compared with irradiation treatment alone. In contrast, post-irradiation sorafenib increased the sensitivity of irradiated SMMC-7221 and BEL-7402 cells significantly in a time-dependent manner. Pre-irradiation sorafenib significantly increased the surviving fraction of SMMC-7221 and BEL-7402 cells in clonogenic assays whereas post-irradiation sorafenib significantly reduced the surviving fractions of SMMC-7221 and BEL-7402 cells. SMMC-7721 cells treated with sorafenib 30 min before irradiation had significantly fewer cells with γ-H2AX foci (23.8 ± 2.9% than SMMC-7721 cells receiving radiation alone (59.9 ± 2.4; P  Conclusions Sorafenib combined with irradiation exerted a schedule-dependent effect in

  17. A Non-standard Empirical Likelihood for Time Series

    DEFF Research Database (Denmark)

    Nordman, Daniel J.; Bunzel, Helle; Lahiri, Soumendra N.

    Standard blockwise empirical likelihood (BEL) for stationary, weakly dependent time series requires specifying a fixed block length as a tuning parameter for setting confidence regions. This aspect can be difficult and impacts coverage accuracy. As an alternative, this paper proposes a new version...... of BEL based on a simple, though non-standard, data-blocking rule which uses a data block of every possible length. Consequently, the method involves no block selection and is also anticipated to exhibit better coverage performance. Its non-standard blocking scheme, however, induces non......-standard asymptotics and requires a significantly different development compared to standard BEL. We establish the large-sample distribution of log-ratio statistics from the new BEL method for calibrating confidence regions for mean or smooth function parameters of time series. This limit law is not the usual chi...

  18. Hepatite C: prevalência e fatores de risco entre portadores do VIH/SIDA em Belém, Pará, na Amazônia brasileira

    Directory of Open Access Journals (Sweden)

    Maria Rita de Cassia Costa Monteiro

    2004-01-01

    Full Text Available Este trabalho objetivou investigar a prevalência de infecção pelo vírus da hepatite C e identificar possíveis fatores de risco para sua transmissão, em 406 indivíduos portadores do vírus da imunodeficiência humana, maiores de dezoito anos de idade, atendidos na rede pública de saúde da cidade de Belém, Pará, situada na Amazônia brasileira. Os exames referentes ao anti-VHC foram realizados pelo método de Elisa e a pesquisa do VHC RNA através da reação de polimerase em cadeia. A prevalência de infecção, atual ou pregressa, pelo vírus da hepatite C foi de 16% (IC: 12,4 - 19,6. A análise multivariada mostrou associação do vírus C com as variáveis idade, cujo risco significante recaiu no grupo com cinqüenta ou mais anos (OR=9,75, antecedente de transfusão de sangue (OR=4,74 e uso de droga ilícita injetável (OR=149,28. A prevalência do vírus da hepatite C entre os usuários de drogas injetáveis foi de 83,7% e de 22,1% na população de transfundidos. Estes resultados indicam a efetiva transmissão do vírus C através da exposição percutânea e reafirmam o grande potencial de risco para hepatite C contido no uso injetável de drogas ilícitas.

  19. Kaks kohvikut

    Index Scriptorium Estoniae

    1998-01-01

    Tallinnas Narva mnt. 7a asuva baar-kohviku "Comet" põhiliseks kujunduselemendiks on valgusinstallatsioon ümber kahe metallposti. Sisekujundus: AS Grünberg. Sisearhitekt Maile Grünberg. Ehitas AS Tonerek. Mööbel: T & T Mang, ETK mööbel. Tallinnas Narva mnt. 6 asuva kohvik-kaupluse "Ebell" kujunduses on kasutatud 1960.-70. aastate andy-warholi-stiilis popkunsti motiive. Sisekujundus: AS Grünberg. Sisearhitekt M. Grünberg. Ehitas Estkompexim Toitlustus Ehitus. Mööbel ja dekoratiivmaalingud: AS Posteral. Toolid: AS Saloni. Kohvikute projektid ja valmimine 1997

  20. Características sobre la tipología y la conformación de las familias de los estratos cero, uno, dos y tres del Barrio Belén Rincón de Medellín

    Directory of Open Access Journals (Sweden)

    José Wilmar Pino Montoya

    2012-01-01

    Full Text Available El siguiente artículo presenta los resultados de la investigación “Características de las familias del barrio Belén Rincón de la ciudad de Medellín”. Se utiliza la metodología cuantitativa, con el tipo de estudio descriptivo, con una encuesta como técnica privilegiada para recoger la información. Los resultados se centran en la tipología familiar por estratos, los ingresos familiares, la distribución por sexo, la distribución por grupos de edad y el tipo de parentesco, además se hizo un balance general de las familias encuestadas y tomadas como muestra. Como conclusiones se puede apreciar que la familia nuclear es superada en este barrio por la familia extensa; en las familias se presentan factores de riesgo como la agresión y la violencia intrafamiliar, es común la familia mono parental. Es pertinente indagar más sobre otros tipos de familia.

  1. Territorialidad y reproducción social: Los tinogasta en Belén, Catamarca, durante el siglo XVIII Territoriality and social reproduction: The tinogasta in Belen, Catamarca. 18th century

    Directory of Open Access Journals (Sweden)

    Federico Ignacio Vázquez

    2011-01-01

    Full Text Available Este trabajo se propone analizar las prácticas de territorialización desplegadas por los Tinogasta en Belén durante el siglo XVIII. Se analizaran los mecanismos jurídicos coloniales a partir de los cuales los Tinogasta buscaron "reterritorializar" su espacio, para recomponer sus condiciones de reproducción social. En este sentido, se observará cómo, frente a diversas prácticas de dominación, algunas poblaciones indígenas implementaron estrategias de resistencia, negociación y/o alianza para reinterpretar la realidad colonial y operar sobre ella. Así, lejos de ser meros espectadores pasivos de su dominio se transformaron en agentes de su reproducción social en un contexto de asimetría.This paper analyzes the practices of territorialization deployed by the Tinogasta in Belen through the 18th century. It will analyze how, through colonial legal mechanisms, the Tinogasta looked for "re-territorialize" their space in order to rebuild their conditions of social reproduction. We intend to observe how some Indian populations implemented multiple resistance, negotiation and/or alliance strategies against diverse domination practices in order to reinterpret -and operate on- the colonial reality. Then, far from being mere passive spectators of their dominance they became agents of their own social reproduction in an asymmetrical context.

  2. TIMP-1 mediates the inhibitory effect of interleukin-6 on the proliferation of a hepatocarcinoma cell line in a STAT3-dependent manner

    Directory of Open Access Journals (Sweden)

    S.-Y. Guo

    2007-05-01

    Full Text Available The tissue inhibitor of metalloproteinases (TIMP-1 is a multifunctional protein which is not only an inhibitor of matrix metalloproteinases (MMPs but also to have a possible "cytokine-like" action. Here, we first compared mRNA expression of TIMP-1 and MMP-9 in BEL-7402 (a hepatocellular carcinoma cell line, L-02 (a normal liver cell line and QSG-7701 (a cell line derived from peripheral tissue of liver carcinoma using real-time quantitative RT-PCR. By evaluating the variation of the MMP-9/TIMP-1 ratio as an index of reciprocal changes of the expression of the two genes, we observed that the MMP-9/TIMP-1 ratio was about 13- and 5-fold higher in BEL-7402 than in L-02 and QSG-7701, respectively. Significantly, overexpression of TIMP-1 decreased the MMP-9/TIMP-1 ratio in BEL-7402 and then inhibited the cell growth to 60% and reduced the migration to about 30%. Meanwhile, our data showed that interleukin-6 (IL-6 (100 ng/mL could also inhibited the cell growth of BEL-7402. Further studies indicated that TIMP-1 mediated the inhibitory effect of IL-6 on BEL-7402 cell proliferation in a STAT3-dependent manner, which could further accelerate the expression of the cyclin-dependent kinase inhibitor p21. A dominant negative STAT3 mutant totally abolished IL-6-induced TIMP-1 expression and its biological functions. The present results demonstrate that TIMP-1 may be one of the mediators that regulate the inhibitory effect of IL-6 on BEL-7402 proliferation in which STAT3 signal transduction and p21 up-regulation also play important roles.

  3. Taso Mähar : maali ümber ehitatud maja / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    220-ruutmeetrise ühekorde eramu sisekujundus. Arhitekt Emil Urbel. Sisearhitekt Taso Mähar, tema kommentaarid. Köögimööbel on T. Mähari projekteeritud. Elutoas mööblifirma T&T Mang pehme mööbel, seinal Lemming Nageli maal "Punane joon all - Burn Out". Ill.: plaan, 17 värv. vaadet

  4. Vaskvilla seinasuuruste akendega / Jana Rand

    Index Scriptorium Estoniae

    Rand, Jana, 1963-

    2008-01-01

    Ehitusettevõtja Indrek Klampe perekonna ebasümmeetriline väljavenitatud viilkatusega villa Võrus. Hoone katus läheb sujuvalt üle seinteks. Arhitekt Karmo Tõra. Sisearhitekt Hillar Mänd. Mööbel tehti eritellimusel firmas Mipla, pehme mööbel firmas Mang. I ja II korruse plaan, 5 värv. välis- ja 7 sisevaadet

  5. Demokratiske møbler

    DEFF Research Database (Denmark)

    Hansen, Per H.

    2014-01-01

    Moderne dansk møbeldesign var totalt dominerende i efterkrigstidens forestillinger om skandinavisk design - alligevel var det IKEA, der blev verdens største møbel- og livsstilsforretning.......Moderne dansk møbeldesign var totalt dominerende i efterkrigstidens forestillinger om skandinavisk design - alligevel var det IKEA, der blev verdens største møbel- og livsstilsforretning....

  6. Full-length genomic and molecular characterization of Canine parvovirus in dogs from North of Brazil.

    Science.gov (United States)

    Silva, S P; Silva, L N P P; Rodrigues, E D L; Cardoso, J F; Tavares, F N; Souza, W M; Santos, C M P; Martins, F M S; Jesus, I S; Brito, T C; Moura, T P C; Nunes, M R T; Casseb, L M N; Silva Filho, E; Casseb, A R

    2017-09-21

    With the objective of characterizing Canine parvovirus (CPV) from some suspected fecal samples of dogs collected from the Veterinarian Hospital in Belém city, five positive samples were found by PCR assay and an update molecular characterization was provided of the CPV-2 circulation in Belém. Through sequencing of the complete DNA sequences (NS1, NS2, VP1, and VP2 genes), the CPV-2 strain was identified as CPV-2b (Asn426Asp) circulating in Belém. The CPV-2b strain with a different change at the position Tyr324Leu was detected in all samples assessed and thus reported for the first time for the scientific community. Phylogenetic analysis indicated that Belém CPV-2b and CPV-2a strains would be related to a cluster with samples after the 1990s, suggesting that CPV-2b in Belém originated from CPV-2a circulating in Brazil after the 1990s. Potential recombination events were analyzed using RDP4 and SplitsTree4; therefore, results suggest that CPV-2 sequences here described were not potentially recombination events. Continuous monitoring and molecular characterization of CPV-2 samples are needed not only to identify possible genetic and antigenic changes that may interfere with the effectiveness of vaccines but also to bring a better understanding of the mechanisms that drive the evolution of CPV-2 in Brazil.

  7. Analysis of the genetic ancestry of patients with oral clefts from South American admixed populations.

    Science.gov (United States)

    Vieira-Machado, Camilla D; de Carvalho, Flavia M; Santana da Silva, Luiz C; Dos Santos, Sidney E; Martins, Claudia; Poletta, Fernando A; Mereb, Juan C; Vieira, Alexandre R; Castilla, Eduardo E; Orioli, Iêda M

    2016-08-01

    Increased susceptibility to cleft lip, with or without cleft palate (CL±P) has been observed in South America, as related to Amerindian ancestry, using epidemiological data, uniparental markers, and blood groups. In this study, it was evaluated whether this increased risk remains when Amerindian ancestry is estimated using autosomal markers and considered in the predictive model. Ancestry was estimated through genotyping 62 insertion and deletion (INDEL) markers in sample sets of patients with CL±P, patients with cleft palate (CP), and controls, from Patagonia in southern Argentina and Belém in northern Brazil. The Amerindian ancestry in patients from Patagonia with CL±P was greater than in controls although it did not reach statistical significance. The European ancestry in patients with CL±P from Belém and in patients with CP from Belém and Patagonia was higher than in controls and statistically significant for patients with CP who were from Belém. This high contribution of European genetic ancestry among patients with CP who were from Belém has not been previously observed in American populations. Our results do not corroborate the currently accepted risks for CL±P and CP estimated by epidemiological studies in the North American populations and probably reflect the higher admixture found in South American ethnic groups when compared with the same ethnic groups from the North American populations. © 2016 Eur J Oral Sci.

  8. The effects of beryllium metal particles on the viability and function of cultured rat alveolar macrophages

    International Nuclear Information System (INIS)

    Finch, G.L.; Lowther, W.T.; Hoover, M.D.; Brooks, A.L.

    1988-01-01

    Rat pulmonary alveolar macrophages (PAM) were exposed in vitro to beryllium metal particles. The particles used were relatively large (Be-II) and small (Be-V) size fractions of beryllium metal obtained from an aerosol cyclone, and a beryllium metal aerosol generated by laser vaporization of beryllium metal in an argon atmosphere (Be-L). Glass beads (GB) were used as a negative control particle. The endpoints examined included cell killing (trypan blue dye exclusion) and phagocytic ability (sheep red blood cell uptake). Phagocytic ability was inhibited by beryllium particles at concentrations that did not cause appreciable cell killing. Results based on the mass concentration of particles in culture medium were transformed by the amount of specific surface area of the particles to permit expression of toxicity on the basis of amount of surface area of particles per unit volume of culture medium. On a mass concentration basis, the order of cytotoxicity was Be-L > Be-V ∼ Be-II > GB; for inhibition of phagacytosis, the cytotoxicity order was Be-L ∼ Be-V > Be-II > GB. On a surface area concentration basis, the order of toxicity for viability was altered to Be-II > Be-L ∼ Be-V (with GB indeterminant) and to Be-V > Be-II ∼ Be-L > GB for inhibition of phagocytosis. We conclude that there are factors in addition to specific surface area that influence the expression of toxic effects in cultured PAM. (author)

  9. Les protéines laitières bouillonnent de propriétés fonctionnelles

    OpenAIRE

    2017-01-01

    Le projet Profil,porté par l'Association Bba, regroupe Bel, CR & R, Isigny StMère, Eurial, Lactalis, Laiterie de Montaigu, Laïta, Savencia, Sill, Entremont-Sodiaal, l’Inra, Oniris, l’Université du Maine, l’Université de Bretagne Occidentale et l’Université de Rennes 1 Le consortium Profil, qui regroupe 80 % de la filière laitière, a présenté mi-septembre les résultats intermédiaires de son méta-projet.[br/] Le but de notre consortium est de monter des projets de recherche pré-...

  10. Classificação climatológica da energia potencial disponível para a convecção na cidade de Belém-PA

    Directory of Open Access Journals (Sweden)

    Josiane Sarmento dos Santos

    2014-12-01

    Full Text Available A classificação climatológica da Energia Potencial Disponível para a Convecção (CAPE foi estudada para verificar a possibilidade de ocorrer convecção e tipo de organização em Belém-PA, Brasil, associando-a com eventos extremos de precipitação (EEPRP. Para a análise da CAPE, utilizou-se dados de radiossondagens do DTCEA e de precipitação da estação do INMET, no período de 1987 a 2011. Observou-se que a atmosfera local apresenta condições favoráveis ao desenvolvimento de convecção profunda, pois a CAPE com valores maiores que 1000 J/kg foi a mais frequente, representando 61% de todas radiossondagens. O valor de 1000 J/kg, segundo alguns autores, é o limite para convecção profunda. As classificações CAPE 2 e 3 apresentaram tendências significativas de aumento ao longo dos anos, enquanto a CAPE 1 diminuição. Essa situação provavelmente é resultado do aumento da temperatura do ar ocorrido na cidade, impactando o valor da CAPE. Os resultados também mostraram que as correlações entre a CAPE e EEPRP, a CAPE e os Índices Oceânico do Pacífico e Gradiente Inter-Hemisférico do Atlântico foram baixas. Então, a CAPE não é condição suficiente para formação de nuvens e precipitação, pois forçantes dinâmicas de meso e grande escala contribuem decisivamente para modular o clima da cidade.

  11. Stratigraphy, geochronology, and paleoenvironments of Miocene - Pliocene boundary of San Fernando, Belén (Catamarca, northwest of Argentina)

    Science.gov (United States)

    Bonini, Ricardo A.; Georgieff, Sergio M.; Candela, Adriana M.

    2017-11-01

    The Santa María-Hualfín Basin was proposed as a regional synchronous lithostratigraphic depocenter in the geological province of Northwestern Pampean Ranges, Northwestern Argentina. However, new 40Ar-39Ar dating indicates that deposits toward the east, in Santa María Valley (Santa María Department), are younger than the western depocenter in San Fernando (Belén Department). Therefore, it would be more appropriate to study these valleys as separate basins, each one with its own tecto-sedimentary features. The east basin, named in this paper Villavil-Quillay, constitutes an elongated independent basin that developed along the front of the eastern Puna bordering with Papachacra and Durazno Ranges. This basin is composed of more than 3000 m of mudstone, sandstone, conglomerates, volcaniclastic and pyroclastic deposits. Villavil-Quillay basin develops onto a peneplain of Precambrian and lower Cambrian rocks, most of which are metamorphic and granites rocks. The sedimentary fill consists of Cretaceous? and Cenozoic continental deposits. The Cenozoic record is composed of a) the Santa María Group (Miocene-Pliocene), formed by Las Arcas, Chiquimil, Andalhuala and Corral Quemado Formations, and b) the Punaschotter unit (Puna's Gravels in German, Pleistocene). This study involves the Andalhuala, Corral Quemado and Punaschotter deposits cropping out in San Fernando area. The set of identified facies assemblage corresponding to the Andalhuala Formation shows a vertical variation of fluvial sub-environments, varying from permanent sandy braided rivers to gravel rivers and aeolian dunes culminating in an alluvial dry cycle. While facies assemblages of the Corral Quemado Formation allow inferring the development of ephemeral water bodies from secondary channels on the floodplain, the Punaschotter conglomerates indicate the development of gravel channels and bars. Three samples of tuffs interbedded in the sedimentary levels of Andalhuala Formation were dated indicating that

  12. Gestão ambiental de parques urbanos: o caso do Parque Ecológico do Município de Belém Gunnar Vingren

    Directory of Open Access Journals (Sweden)

    Silvia Laura Costa Cardoso

    2014-01-01

    Full Text Available O artigo debate fatores que facilitam e dificultam a implementação de um parque urbano. Discutem-se as facilidades e dificuldades inerentes à implementação de parques urbanos face aos múltiplos interesses que envolvem os atores sociais. Analisa-se o caso do Parque Ecológico do Município de Belém Gunnar Vingren (PEGV e enfocam-se os conceitos de participação, governança urbana e gestão ambiental. Utiliza-se da teoria dos stakeholders para identificação dos atores sociais e interpretação de seus comportamentos no processo de implementação do parque. Metodologicamente, o trabalho assume a abordagem qualitativa e se utiliza da observação direta e entrevistas semiestruturadas. O estudo mostra a importância dos movimentos sociais urbanos para a preservação das áreas verdes da cidade e melhoria da qualidade de vida urbana. Aponta que a gestão ambiental dos parques urbanos depende fundamentalmente do ordenamento do seu próprio território e entorno. Em áreas com território desordenado é elevada a possibilidade de pressão sobre parque e depredação dos seus recursos naturais. A pesquisa mostra que os modelos de gestão urbana da cidade influenciam no nível de participação dos atores sociais nos conselhos gestores de parques. Empiricamente, o artigo mostra que a capacidade institucional para a gestão do PEGV avançou bastante; todavia, paradoxalmente, a capacidade organizacional do governo municipal é limitada para a gestão de todo o sistema. Dentre todos os desafios na gestão de parques urbanos, o mais proeminente é o de construção de uma aliança de governança participativa entre os stakeholders.

  13. Effects of sodium phenylbutyrate on differentiation and induction of the P21WAF1/CIP1 anti-oncogene in human liver carcinoma cell lines.

    Science.gov (United States)

    Meng, Mei; Jiang, Jun Mei; Liu, Hui; In, Cheng Yong; Zhu, Ju Ren

    2005-01-01

    To explore the effects of sodium phenylbutyrate on the proliferation, differentiation, cell cycle arrest and induction of the P(21WAF1/CIP1) anti-oncogene in human liver carcinoma cell lines Bel-7402 and HepG2. Bel-7402 and HepG2 human liver carcinoma cells were treated with sodium phenylbutyrate at different concentrations. Light microscopy was used to observe morphological changes in the carcinoma cells. Effects on the cell cycle were detected by using flow cytometry. P(21WAF1/CIP1) expression was determined by both reverse transcription-polymerase chain reaction and western blotting. Statistical analysis was performed by using one-way anova and Student's t-test. Sodium phenylbutyrate treatment caused time- and dose-dependent growth inhibition of Bel-7402 and HepG2 cells. This treatment also caused a decline in the proportion of S-phase cells and an increase in the proportion of G(0)/G(1) cells. Sodium phenylbutyrate increased the expression of P(21WAF1/CIP1). Sodium phenylbutyrate inhibits the proliferation of human liver carcinoma cells Bel-7402 and HepG2, induces partial differentiation, and increases the expression of P(21WAF1/CIP1).

  14. Structure of a lectin with antitumoral properties in king bolete (Boletus edulis) mushrooms.

    Science.gov (United States)

    Bovi, Michele; Carrizo, Maria E; Capaldi, Stefano; Perduca, Massimiliano; Chiarelli, Laurent R; Galliano, Monica; Monaco, Hugo L

    2011-08-01

    A novel lectin has been isolated from the fruiting bodies of the common edible mushroom Boletus edulis (king bolete, penny bun, porcino or cep) by affinity chromatography on a chitin column. We propose for the lectin the name BEL (B. edulis lectin). BEL inhibits selectively the proliferation of several malignant cell lines and binds the neoplastic cell-specific T-antigen disaccharide, Galβ1-3GalNAc. The lectin was structurally characterized: the molecule is a homotetramer and the 142-amino acid sequence of the chains was determined. The protein belongs to the saline-soluble family of mushroom fruiting body-specific lectins. BEL was also crystallized and its three-dimensional structure was determined by X-ray diffraction to 1.15 Å resolution. The structure is similar to that of Agaricus bisporus lectin. Using the appropriate co-crystals, the interactions of BEL with specific mono- and disaccharides were also studied by X-ray diffraction. The six structures of carbohydrate complexes reported here provide details of the interactions of the ligands with the lectin and shed light on the selectivity of the two distinct binding sites present in each protomer.

  15. Qualidade de vida de pacientes em hemodiálise em um hospital público de Belém - Pará Quality of life of hemodialysis patients in a Brazilian Public Hospital in Belém - Pará

    Directory of Open Access Journals (Sweden)

    Cíntia Botelho Silveira

    2010-03-01

    Full Text Available INTRODUÇÃO: A doença renal crônica (DRC dialítica afeta a qualidade de vida do paciente, por vezes de maneira mais intensa que outras doenças crônicas, como artrite reumatóide, insuficiência cardíaca, doença arterial coronariana e doença pulmonar obstrutiva crônica, exercendo efeito negativo sobre os níveis de energia e vitalidade, limitando as interações sociais e prejudicando a saúde psíquica. OBJETIVO: Avaliar a qualidade de vida de pacientes com IRC em programa de hemodiálise ambulatorial em um hospital público de Belém - Pará. MÉTODO: O estudo baseou-se em dados coletados em entrevista, utilizando a versão brasileira do questionário SF-36. Foram avaliados 50 pacientes, com idade média de 48 ± 16 anos e tempo médio em hemodiálise de 3 ± 2,9 anos, 62% do sexo masculino. RESULTADOS: A dimensão mais afetada foi relativa aos aspectos físicos, com pontuação média de 36 ± 36 e 58% dos pacientes no quartil mais baixo, enquanto saúde mental e aspectos sociais demonstraram relativa preservação, com a maioria dos pacientes alocados no quartil mais elevado. A população masculina apresentou piores escores que a feminina quanto a aspectos físicos e vitalidade. A idade correlacionou-se negativamente com a capacidade funcional. Os pacientes em hemodiálise há mais de um ano apresentaram melhores níveis no domínio aspectos sociais e houve correlação positiva entre o tempo em diálise e a capacidade funcional. CONCLUSÃO: Os domínios analisados estiveram globalmente comprometidos na população estudada, em especial com relação aos aspectos físicos, sugerindo a influência negativa da presença de doença crônica, com tratamento prolongado, sobre esses âmbitos.INTRODUCTION: End-stage chronic kidney disease (CKD requiring dialysis affects the quality of life sometimes more severely than other chronic diseases, such as rheumatoid arthritis, heart failure, coronary artery disease, and chronic obstructive

  16. Nutritional status in relation to the efficacy of the rhesus-human reassortant, tetravalent rotavirus vaccine (RRV-TV in infants from Belém, Pará State, Brazil Relação entre o estado nutricional e a eficácia da vacina tetravalente contra rotavírus de origem símio-humana, geneticamente rearranjada (RRV-TV, em crianças de Belém, Pará, Brasil

    Directory of Open Access Journals (Sweden)

    Alexandre C. LINHARES

    2002-02-01

    Full Text Available The rhesus-human reassortant, tetravalent rotavirus vaccine (RRV-TV was licensed for routine use in the United States of America but it was recently withdrawn from the market because of its possible association with intussusception as an adverse event. The protective efficacy of 3 doses of RRV-TV, in its lower-titer (4 x 10(4 pfu/dose formulation, was evaluated according to the nutritional status of infants who participated in a phase III trial in Belém, Northern Brazil. A moderate protection conferred by RRV-TV was related to weight-for-age Z-scores (WAZ greater than -1 only, with rates of 38% (p = 0.04 and 40% (p = 0.04 for all- and- pure rotavirus diarrhoeal cases, respectively. In addition, there was a trend for greater efficacy (43%, p = 0.05 among infants reaching an height-for-age Z-score (HAZ of > -1. Taking WAZ, HAZ and weight-for-height Z-score (WHZ indices 0.05 if both placebo and vaccine groups are compared. There was no significant difference if rates of mixed and pure rotavirus diarrhoeal cases are compared in relation to HAZ, WAZ and weight-for-height Z-score (WHZ indices. Although a low number of malnourished infants could be identified in the present study, our data show some evidence that malnutrition may interfere with the efficacy of rotavirus vaccines in developing countries.A vacina tetravalente contra rotavírus de origem símio-humana, geneticamente rearranjada (RRV-TV, foi licenciada para uso rotineiro nos Estados Unidos da América do Norte; entretanto, tal imunizante foi removido do mercado, uma vez que a intussuscepção emergiu como possível evento adverso vacinal. A eficácia da RRV-TV - em sua formulação menos concentrada (10 x 10(4 pfu/dose - foi avaliada no tocante ao estado nutricional das crianças que integraram estudo caracterizado como de fase III, levado a efeito em Belém, região norte do Brasil. Observou-se proteção (moderada apenas entre os indivíduos com escore "Z" (peso-por-idade, WAZ superior

  17. O espaço para crianças produzido pelo Programa Minha Casa, Minha Vida: estudo de caso na região metropolitana de Belém, PA

    Directory of Open Access Journals (Sweden)

    Shirley Coelho Müller

    Full Text Available Resumo A atual política de habitação de interesse social no Brasil determina que o lazer infantil seja atendido por espaços construídos especificamente para esse fim. Este artigo traz os resultados de pesquisa de espaços projetados para o lazer infantil em dois conjuntos habitacionais de interesse social produzidos pelo Programa Minha Casa, Minha Vida, Jardim Campo Grande e Jardim dos Pardais, ambos na Região Metropolitana de Belém, no Pará. Indaga-se que espaços de fato têm sido produzidos, partindo-se do princípio de que o corpo em movimento no espaço e as interações sociais possibilitadas pelo lazer são fundamentais para que o desenvolvimento sócio-cognitivo e psicomotor das crianças aconteça de forma satisfatória. Investiga-se também a efetiva utilização desses espaços pelas crianças. O método de estudo de caso combina técnicas de análise do projeto arquitetônico e do espaço físico com a observação comportamental das crianças em seu lazer. Observou-se que os espaços de lazer infantil dos conjuntos estudados carecem de elementos que atendam de forma adequada à necessidade de lazer das crianças, que seu uso independe da quantidade de área destinada a esse fim, e que fatores como sensação de segurança ou insegurança e tipologia habitacional podem limitar ou estimular o uso desses espaços e a apropriação dos espaços comuns.

  18. Introducing the Guard-Stage-Milestone Approach for Specifying Business Entity Lifecycles

    Science.gov (United States)

    Hull, Richard; Damaggio, Elio; Fournier, Fabiana; Gupta, Manmohan; Heath, Fenno (Terry); Hobson, Stacy; Linehan, Mark; Maradugu, Sridhar; Nigam, Anil; Sukaviriya, Piyawadee; Vaculin, Roman

    A promising approach to managing business operations is based on business entities with lifecycles (BEL's) (a.k.a. business artifacts), i.e., key conceptual entities that are central to guiding the operations of a business, and whose content changes as they move through those operations. A BEL type includes both an information model that captures, in either materialized or virtual form, all of the business-relevant data about entities of that type, and a lifecycle model, that specifies the possible ways an entity of that type might progress through the business by responding to events and invoking services, including human activities. Most previous work on BEL's has focused on the use of lifecycle models based on variants of finite state machines. This paper introduces the Guard-Stage-Milestone (GSM) meta-model for lifecycles, which is an evolution of the previous work on BEL's. GSM lifecycles are substantially more declarative than the finite state machine variants, and support hierarchy and parallelism within a single entity instance. The GSM operational semantics are based on a form of Event-Condition-Action (ECA) rules, and provide a basis for formal verification and reasoning. This paper provides an informal, preliminary introduction to the GSM approach, and briefly overviews selected research directions.

  19. BELÉM E A BELLE ÉPOQUE DA BORRACHA

    Directory of Open Access Journals (Sweden)

    Geraldo Mártires Coelho

    2016-12-01

    Full Text Available O artigo discute a história e a vida de Belém na passagem do século XIX para o século XX, marcada por um conjunto de elementos sociais, intelectuais e artísticos que refletiam as influências da cultura e da sociedade europeia, principalmente francesa, do período. Em termos de Brasil, esse processo se verificou em Belém e no Rio de Janeiro: era a chamada Belle Époque. Cultivou-se o gosto pelo que vinha da Europa, o que podia ser visto na maneira de se vestir das elites locais e na vida social que levavam em Belém. A literatura, a pintura e a música, cultuadas por essas mesmas elites, faziam da cidade um grande centro de vida intelectual e artística. É preciso, no entanto, observar que a Belle Époque faz parte de um processo maior, o da mundialização da cultura.   PALAVRAS-CHAVE: Belém; Belle Époque; Mundialização da cultura.     ABSTRACT This article treats the history and life of Belem (capital city of Para State/Brazil during the passage from XIX to XX century that was marked by a set of social, intellectual and artistic elements, which reflected the influences from European culture and society, especially the French one in such period. In terms of Brazil, that process was seen in Belem and Rio de Janeiro; it was called Belle Époque. It was cultivated a taste to whatever came from Europe, what could be seen on the dressing fashion of the local elites and the social live they had in Belem. Literature, painting and music, idolised by the same elite made the city a huge centre of intellectual and artistic life. However, it is needed to consider that Belle Époque is part of a bigger process, the globalization one.   KEY WORDS: Belém; Belle Époque; Culture globalization.   RESUMEN  El artículo discute la historia de la vida de Belém en la pasaje del siglo XIX para el siglo XX, marcada por un conjunto de elementos sociales, intelectuales y artísticos que reflejaban las influencias de la cultura y de la sociedad

  20. Haljalas valmistatud pehme mööbel vallutab Skandinaavia kodusid / Signe Kalberg

    Index Scriptorium Estoniae

    Kalberg, Signe, 1959-

    2009-01-01

    Edukast pehme mööbli firmast Bellus Furniture. Ajakohased tootmisliinid võimaldavad valmistada 160 mööblimudelit. 98 % firma toodangust läheb ekspordiks Rootsi, Soome, Norrasse, Taani ja Beneluxi maadesse. Omanikud: Rolf ja Rikard Mikael Relander. Disainerid: Heikki Toripainen ja Kaie Veissbach

  1. Importância das condições termodinâmicas nos eventos extremos de precipitação na cidade de Belém e região metropolitana

    Directory of Open Access Journals (Sweden)

    Felipe do Souto de Sá Gille

    2014-12-01

    Full Text Available O objetivo desta pesquisa foi verificar a importância dos fatores termodinâmicos na ocorrência de eventos extremos de precipitação em Belém (PA e região metropolitana, no período de agosto de 2008 a dezembro de 2009. O estudo da termodinâmica da atmosfera foi realizado a luz das teorias da Energia Potencial Disponível para a Convecção (CAPE e, da Energia de Inibição da Convecção (CINE. Para classificar os eventos extremos de precipitação foi utilizado o método dos decis, a fim de associá-los aos valores da CAPE e da CINE. Observou-se que a região estudada possui forte atividade convectiva durante todo o ano, e que nem sempre CAPE alta e CINE baixa produz precipitação. Esta situação determina convecção profunda, mas para haver precipitação existe a necessidade da forçante dinâmica, inclusive para a ocorrência de eventos extremos de precipitação no período chuvoso a forçante dinâmica é a ITCZ, e no período seco o que contribui é a Linha de Instabilidade (LI. Então quando o processo de precipitação dependeu, exclusivamente, da CAPE, foi necessário um valor alto para gerar convecção profunda e por consequência precipitação, enquanto, que no processo de precipitação com contribuição dinâmica não foi necessário um valor tão significativo da CAPE.

  2. Inhibition of heat-shock protein 90 sensitizes liver cancer stem-like cells to magnetic hyperthermia and enhances anti-tumor effect on hepatocellular carcinoma-burdened nude mice

    Science.gov (United States)

    Yang, Rui; Tang, Qiusha; Miao, Fengqin; An, Yanli; Li, Mengfei; Han, Yong; Wang, Xihui; Wang, Juan; Liu, Peidang; Chen, Rong

    2015-01-01

    Purpose To explore the thermoresistance and expression of heat-shock protein 90 (HSP90) in magnetic hyperthermia-treated human liver cancer stem-like cells (LCSCs) and the effects of a heat-shock protein HSP90 inhibitor 17-allylamino-17-demethoxgeldanamycin (17-AAG) on hepatocellular carcinoma-burdened nude mice. Methods CD90+ LCSCs were isolated by magnetic-activated cell sorting from BEL-7404. Spheroid formation, proliferation, differentiation, drug resistance, and tumor formation assays were performed to identify stem cell characteristics. CD90-targeted thermosensitive magnetoliposomes (TMs)-encapsulated 17-AAG (CD90@17-AAG/TMs) was prepared by reverse-phase evaporation and its characteristics were studied. Heat tolerance in CD90+ LCSCs and the effect of CD90@17-AAG/TMs-mediated heat sensitivity were examined in vitro and in vivo. Results CD90+ LCSCs showed significant stem cell-like properties. The 17-AAG/TMs were successfully prepared and were spherical in shape with an average size of 128.9±7.7 nm. When exposed to magnetic hyperthermia, HSP90 was up-regulated in CD90+ LCSCs. CD90@17-AAG/TMs inhibited the activity of HSP90 and increased the sensitivity of CD90+ LCSCs to magnetic hyperthermia. Conclusion The inhibition of HSP90 could sensitize CD90+ LCSCs to magnetic hyperthermia and enhance its anti-tumor effects in vitro and in vivo. PMID:26677324

  3. Multifractal analysis of vertical total electron content (VTEC at equatorial region and low latitude, during low solar activity

    Directory of Open Access Journals (Sweden)

    M. J. A. Bolzan

    2013-01-01

    Full Text Available This paper analyses the multifractal aspects of the GPS data (measured during a period of low solar activity obtained from two Brazilian stations: Belém (01.3° S, 48.3° W and São José dos Campos (SJC (23.2° S, 45.9° W. The results show that the respective geographic sites show important scaling differences as well as similarities when their multifractal signatures for vertical total electron content (VTEC are compared. The f(α spectra have a narrow shape for great scales, which indicates the predominance of deterministic phenomena, such as solar rotation (27 days over intermittent phenomena. Furthermore, the f(α spectra for both sites have a strong multifractality degree at small scales. This strong multifractality degree observed at small scales (1 to 12 h at both sites is because the ionosphere over Brazil is a non-equilibrium system. The differences found were that Belém presented a stronger multifractality at small scales (1 h to 12 h compared with SJC, particularly in 2006. The reason for this behaviour may be associated with the location of Belém, near the geomagnetic equator, where at this location the actions of X-rays, ultraviolet, and another wavelength from the Sun are more direct, strong, and constant throughout the whole year. Although the SJC site is near ionospheric equatorial anomaly (IEA peaks, this interpretation could explain the higher values found for the intermittent parameter μ for Belém compared with SJC. Belém also showed the presence of one or two flattening regions for f(α spectra at the same scales mentioned before. These differences and similarities also were interpreted in terms of the IEA content, where this phenomenon is an important source of intermittence due the presence of the VTEC peaks at ±20° geomagnetic latitudes.

  4. Marine Bromophenol Bis (2,3-Dibromo-4,5-dihydroxy-phenyl-methane Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Modulating β1-Integrin/FAK Signaling

    Directory of Open Access Journals (Sweden)

    Ning Wu

    2015-02-01

    Full Text Available Bis (2,3-dibromo-4,5-dihydroxy-phenyl-methane (BDDPM is a natural bromophenol compound derived from marine algae. Previous reports have shown that BDDPM possesses antimicrobial activity. In the present study, we found that BDDPM has cytotoxic activity on a wide range of tumor cells, including BEL-7402 cells (IC50 = 8.7 μg/mL. Further studies have shown that prior to the onset of apoptosis, the BDDPM induces BEL-7402 cell detachment by decreasing the adherence of cells to the extracellular matrix (ECM. Detachment experiments have shown that the treatment of BEL-7402 cells with low concentrations of BDDPM (5.0 μg/mL significantly inhibits cell adhesion to fibronectin and collagen IV as well as cell migration and invasion. High doses of BDDPM (10.0 μg/mL completely inhibit the migration of BEL-7402 cells, and the expression level of MMPs (MMP-2 and MMP-9 is significantly decreased. Moreover, the expression of β1-integrin and focal adhesion kinase (FAK is found to be down-regulated by BDDPM. This study suggests that BDDPM has a potential to be developed as a novel anticancer therapeutic agent due to its anti-metastatic activity and also indicates that BDDPM, which has a unique chemical structure, could serve as a lead compound for rational drug design and for future development of anticancer agents.

  5. Kujundusideid

    Index Scriptorium Estoniae

    2005-01-01

    Aet Pieli projekteeritud minimalistlik ja eestiaegses majas asuv köök. Vana muljega köök, mille mööbel on valmistatud firmas Moons. Kadri Pärtelpoja projekteeritud ehitusfirma NCC kinnisvaraosakonna paekiviseintega näidisköök. Köök Ivi-Els Schneideri kujundatud elamus. Hansperdis disainitud ja valmistatud noore perekonna erksates toonides köögimööbel. Arensis disainitud ja valmistatud seriaali "Kodu keset linna" köök. 22 värv. ill

  6. Projeto BaBel: uma proposta de desenvolvimento comunitário sustentável em Baselstrasse (Lucerna –Suíça (The BaBeL Project, Sustainable Neighbourhood Development in Lucerne’s Baselstrasse/Bernstrasse Neighbourhood

    Directory of Open Access Journals (Sweden)

    Alex Willener

    2008-01-01

    Full Text Available Resumo: A comunidade de Baselstrasse/Bernstrasse em Lucerna, Suíça, é caracterizada por conter uma população multinacional formada por mais de 70 nações, todas mantendo seus específicos estilos de vida. O aumento da população economicamente pobre refletiu na reputação da comunidade de forma negativa. A dinâmica social dessa comunidade repercutiu, também, nos aspectos educacionais e sócio-culturais da região, levando professores e outros profissionais a enfrentarem grandes desafios. Uma equipe interdisciplinar formada por professores da Universidade de Ciências Sociais Aplicadas de Lucerna aceitou o desafio de trabalhar com a comunidade e desenvolveu um projeto denominado BaBel. O principal objetivo do Projeto BaBel era desenvolver um trabalho que trouxesse benefícios para os diferentes grupos que vivem na comunidade, para as instituições presentes no local, bem como criar espaços para os futuros stakeholders. Todos esses atores foram envolvidos no desenvolvimento do projeto. Diferentes metodologias foram utilizadas para fomentar a participação progressiva da população, tais como: ‘desenvolvimento de cenários’, grupos de intervenção, análise da comunidade realizada pelas crianças e pelos jovens. A implementação do projeto envolveu 16 diferentes campos de ação, os quais abarcaram temas como economia de energia e poluição sonora (projetos pilotos, projetos na área da infância (curricular e extracurricular, melhoria das áreas de proteção ambiental das margens do rio que corta a comunidade, melhoria dos espaços de lazer, saúde e prevenção, estabelecimento de pontos de encontro na área, melhoria nas estruturas comerciais e otimização do tráfego local.Abstract: The Baselstrasse/Bernstrasse neighbourhood is characterized by its multinational population hailing from 70 nations, all maintaining their specific lifestyles. The increase in the number of economically weak people to a level above average

  7. Bel Paese or Spaghetti noir?

    DEFF Research Database (Denmark)

    Jansen, Hanne

    2016-01-01

    ’ Italian in the eyes of Danes? I will look at translations of contemporary Italian narrative, relying primarily on the website of the Danish public libraries, bibliotek.dk, that contains keyword categorizations and evaluations produced by the librarians in order to “mediate” between the foreign texts...

  8. Tshorno-belõje kartinki istorii

    Index Scriptorium Estoniae

    2008-01-01

    Ekskursioon "Seenioride reede" Kumus 29. veebruaril tutvustab Liina Siibi koostatud näitust "Reis maale. Etnograafilised tüübid fotos". Näha etnograafilised fotod Eestist, põhirõhuga Johannes Pääsukese Setumaa ja Saaremaa piltidel. Kadrioru Kunstimuuseumis avatud näitusest "Igatsedes mägesid. Šveitsi maastikud Balti kunstis". Vahendatakse Balti kunstnike joonistusi Šveitsi-reisidelt ja Šveitsi maastikumaalijate loomingut. Kuraator Kadri Polli

  9. L’heure du tacacá.

    Directory of Open Access Journals (Sweden)

    Lucia van Velthem

    2008-05-01

    Full Text Available En fin d’après-midi, de nombreux citadins viennent déguster un tacacá dans les kiosques installés sur les trottoirs de Belém et autres grandes villes amazoniennes. À base de manioc, exigeant une préparation élaborée réservée à des spécialistes locaux et associé à une commensalité urbaine, le tacacá constitue un exemple paradigmatique des nourritures de rue auxquelles se rapportent des valeurs identitaires. L’article décrit les continuités et les innovations dans les mani��res de fabriquer, de consommer et de percevoir le plat alors qu’il s’impose comme « spécialité régionale ».Tacacá time. Consumption and valorization of traditional Amazonian foods in urban areas (Brazil In Belém and other large cities of the Amazon, in the late afternoon, many people can be seen eating tacacá in the street food stalls. The tacacá, made from cassava products, requires elaborate processing known only by local specialists. Associated to urban commensality, the tacacá, as a street food, also carries identity values. Since this dish is emerging as a “regional speciality”, the article describes changes and continuity in the ways it is prepared, consumed and perceived.

  10. Conservation of polypyrimidine tract binding proteins and their putative target RNAs in several storage root crops.

    Science.gov (United States)

    Kondhare, Kirtikumar R; Kumar, Amit; Hannapel, David J; Banerjee, Anjan K

    2018-02-07

    Polypyrimidine-tract binding proteins (PTBs) are ubiquitous RNA-binding proteins in plants and animals that play diverse role in RNA metabolic processes. PTB proteins bind to target RNAs through motifs rich in cytosine/uracil residues to fine-tune transcript metabolism. Among tuber and root crops, potato has been widely studied to understand the mobile signals that activate tuber development. Potato PTBs, designated as StPTB1 and StPTB6, function in a long-distance transport system by binding to specific mRNAs (StBEL5 and POTH1) to stabilize them and facilitate their movement from leaf to stolon, the site of tuber induction, where they activate tuber and root growth. Storage tubers and root crops are important sustenance food crops grown throughout the world. Despite the availability of genome sequence for sweet potato, cassava, carrot and sugar beet, the molecular mechanism of root-derived storage organ development remains completely unexplored. Considering the pivotal role of PTBs and their target RNAs in potato storage organ development, we propose that a similar mechanism may be prevalent in storage root crops as well. Through a bioinformatics survey utilizing available genome databases, we identify the orthologues of potato PTB proteins and two phloem-mobile RNAs, StBEL5 and POTH1, in five storage root crops - sweet potato, cassava, carrot, radish and sugar beet. Like potato, PTB1/6 type proteins from these storage root crops contain four conserved RNA Recognition Motifs (characteristic of RNA-binding PTBs) in their protein sequences. Further, 3´ UTR (untranslated region) analysis of BEL5 and POTH1 orthologues revealed the presence of several cytosine/uracil motifs, similar to those present in potato StBEL5 and POTH1 RNAs. Using RT-qPCR assays, we verified the presence of these related transcripts in leaf and root tissues of these five storage root crops. Similar to potato, BEL5-, PTB1/6- and POTH1-like orthologue RNAs from the aforementioned storage root

  11. Algúns conceptos básicos de radiometría e fotometría

    OpenAIRE

    Flores Seijas, José Ramón

    2013-01-01

    Licenciatura de Física Os optoelectrónicos son dispositivos de base electrónica que emiten, modulan ou detectan radiación óptica, i.e. radiación electromagnética ultravioleta, visíbel ou infravermella. A maior parte deste tipo de dispositivos están baseados en semicondutores inorgánicos, se ben é posíbel que nun futuro os semicondutores orgánicos pasen a desempeñar un papel máis importante. Nesta unidade introdúcense unha serie de conceptos relacionados coa radiación electromagn...

  12. Tuntud tegijatelt tuntud headuses / Ado Eigi

    Index Scriptorium Estoniae

    Eigi, Ado, 1938-2008

    1998-01-01

    Neljatoalise korteri ümberehitus, mille tulemusena sai esik juurde seinakapi, tekkis majapidamisruum, sauna eesruum, kujunes otseühendus sauna ning dushiruumi vahel. Endine söögituba poolitati kaheks lastetoaks. Voolava ruumi põhimõttel lahendatud korteris markeerib ruumifunktsiooni üleminekut vaid põrandamaterjali muutus köögi ja elutoa vahel, esiku allalastud lagi. Köögi- ja lastetoa mööbel ning esikukapi uksed Perfetto Stuudiost, elutoa- ja magamistoa mööbel Inspirast. Tualettlaud valmistati ASs Disket korteri kujundajate Argo ja Katrin Vaikla jooniste järgi

  13. Novel bio-inspired smart control for hazard mitigation of civil structures

    International Nuclear Information System (INIS)

    Kim, Yeesock; Kim, Changwon; Langari, Reza

    2010-01-01

    In this paper, a new bio-inspired controller is proposed for vibration mitigation of smart structures subjected to ground disturbances (i.e. earthquakes). The control system is developed through the integration of a brain emotional learning (BEL) algorithm with a proportional–integral–derivative (PID) controller and a semiactive inversion (Inv) algorithm. The BEL algorithm is based on the neurologically inspired computational model of the amygdala and the orbitofrontal cortex. To demonstrate the effectiveness of the proposed hybrid BEL–PID–Inv control algorithm, a seismically excited building structure equipped with a magnetorheological (MR) damper is investigated. The performance of the proposed hybrid BEL–PID–Inv control algorithm is compared with that of passive, PID, linear quadratic Gaussian (LQG), and BEL control systems. In the simulation, the robustness of the hybrid BEL–PID–Inv control algorithm in the presence of modeling uncertainties as well as external disturbances is investigated. It is shown that the proposed hybrid BEL–PID–Inv control algorithm is effective in improving the dynamic responses of seismically excited building structure–MR damper systems

  14. Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts

    DEFF Research Database (Denmark)

    Pedersen, Stine Helene Falsig; Poulsen, Kristian Arild; Lambert, Ian H.

    2006-01-01

    Osmotic swelling of NIH3T3 mouse fibroblasts activates a bromoenol lactone (BEL)-sensitive taurine efflux, pointing to the involvement of a Ca2+-independent phospholipase A2 (iPLA2) (Lambert IH. J Membr Biol 192: 19-32, 2003). We report that taurine efflux from NIH3T3 cells was not only increased...... by cell swelling but also decreased by cell shrinkage. Arachidonic acid release to the cell exterior was similarly decreased by shrinkage yet not detectably increased by swelling. NIH3T3 cells were found to express cytosolic calcium-dependent cPLA2-IVA, cPLA2-IVB, cPLA2-IVC, iPLA2-VIA, iPLA2-VIB......, and secretory sPLA2-V. Arachidonic acid release from swollen cells was partially inhibited by BEL and by the sPLA2-inhibitor manoalide. Cell swelling elicited BEL-sensitive arachidonic acid release from the nucleus, to which iPLA2-VIA localized. Exposure to the bee venom peptide melittin, to increase PLA2...

  15. A Comparative Study on Turpentine Oils of Oleoresins of Pinus sylvestris L. from Three Districts of Denizli

    Directory of Open Access Journals (Sweden)

    İbrahim Tümen

    2010-10-01

    Full Text Available Oleoresin samples collected from Pinus sylvestris L. trees from Acıpayam, Çal and Çamlıbel, three different locations in Denizli-Turkey. The constituents of the turpentine oil, obtained by hydrodistillation of oleoresin of Pinus sylvestris L., were identified by GC-MS. Fifty four constituents were detected from the turpentine oil, which constituted about between 96.2% and 98.2% of the total amount. Major constituents of the oil were a-pinene, b-pinene, camphene, longifolene, D3-carene, limonene and b-caryophyllene

  16. Nidificação de aves em duas localidades amazonicas : sucesso e adaptações

    OpenAIRE

    Yoshika Oniki Willis

    1986-01-01

    Resumo: As taxas de sucesso em ninhos de aves bera como as características de ninhos e ovos relacionados com o ambiente foram estudadas em duas localidades brasileiras tropicais, Belém e Manaus. As taxas de mortalidade em ninhos de aves, de Belém e Manaus, medidas pela fórmula N/(P + S + N), sugerida por Mayfield (1975) variaram entre 1,5 e 6,8 % por dia para diferentes tipos de ninhos e habitats. Sendo que estas figuras às vezes não são significantemente mais altas que taxas constatadas em z...

  17. The Sinbad retrotransposon from the genome of the human blood fluke, Schistosoma mansoni, and the distribution of related Pao-like elements

    Directory of Open Access Journals (Sweden)

    Morales Maria E

    2005-02-01

    Full Text Available Abstract Background Of the major families of long terminal repeat (LTR retrotransposons, the Pao/BEL family is probably the least well studied. It is becoming apparent that numerous LTR retrotransposons and other mobile genetic elements have colonized the genome of the human blood fluke, Schistosoma mansoni. Results A proviral form of Sinbad, a new LTR retrotransposon, was identified in the genome of S. mansoni. Phylogenetic analysis indicated that Sinbad belongs to one of five discreet subfamilies of Pao/BEL like elements. BLAST searches of whole genomes and EST databases indicated that members of this clade occurred in species of the Insecta, Nematoda, Echinodermata and Chordata, as well as Platyhelminthes, but were absent from all plants, fungi and lower eukaryotes examined. Among the deuterostomes examined, only aquatic species harbored these types of elements. All four species of nematode examined were positive for Sinbad sequences, although among insect and vertebrate genomes, some were positive and some negative. The full length, consensus Sinbad retrotransposon was 6,287 bp long and was flanked at its 5'- and 3'-ends by identical LTRs of 386 bp. Sinbad displayed a triple Cys-His RNA binding motif characteristic of Gag of Pao/BEL-like elements, followed by the enzymatic domains of protease, reverse transcriptase (RT, RNAseH, and integrase, in that order. A phylogenetic tree of deduced RT sequences from 26 elements revealed that Sinbad was most closely related to an unnamed element from the zebrafish Danio rerio and to Saci-1, also from S. mansoni. It was also closely related to Pao from Bombyx mori and to Ninja of Drosophila simulans. Sinbad was only distantly related to the other schistosome LTR retrotransposons Boudicca, Gulliver, Saci-2, Saci-3, and Fugitive, which are gypsy-like. Southern hybridization and bioinformatics analyses indicated that there were about 50 copies of Sinbad in the S. mansoni genome. The presence of ESTs

  18. Trois palmiers pour trois capitales amazoniennes

    Directory of Open Access Journals (Sweden)

    1997-01-01

    Full Text Available Les trois grandes capitales amazoniennes ont leur palmier préféré : Euterpe oleracea à Belém, Astrocaryum aculeatum à Manaus, Mauritia flexuosa à Iquitos. Le premier cas trouve une explication simple : Euterpe oleracea est abondant dans la région de Belém et absent des deux autres régions. Les deux autres cas sont plus complexes, car Astrocaryum aculeatum a été propagé, sous l’effet des activités anthropiques, dans la région de Manaus et Mauritia flexuosa, dont l’aire de répartition couvre toute l’Amazonie, ne connaît un réel succès que dans la région occidentale, au Pérou. Ces trois exemples soulignent l’importance des cultures régionales qui conduisent à des utilisations différentes, parfois restrictives, des ressources naturelles et peuvent ainsi constituer une entrave à la mise en valeur du milieu forestier. TRES PALMERAS PARA TRES CAPITALES AMAZÓNICAS. Cada una de las tres grandes capitales amazónicas tiene su palma preferida: Euterpe oleracea es preciada en Belén, Astrocaryum aculeatum en Manaos, y Mauritia flexuosa en Iquitos. El primer caso tiene una explicación simple: Euterpe oleracea abunda en la región de Belén y es ausente en las dos otras regiones. Los dos otros casos se deben a razones más complejas, pues Astrocaryum aculeatum se ha propagado con el efecto de las actividades antrópicas en la región de Manaos, y Mauritia flexuosa, cuya área de distribución cubre toda Amazonía, es afamado únicamente en la región occidental, en el Perú. Estos tres ejemplos ponen de manifiesto la importancia de las culturas regionales que acarrean utilizaciones diferentes, a veces restrictivas, de los recursos naturales y pueden así constituir una traba al manejo del medio selvático. THREE PALMS FOR THREE AMAZONIAN CAPITAL CITIES. Each of the three Amazonian capital cities has its favorite palm: Euterpe oleracea for Belém, Astrocaryum aculeatum for Manaus, and Mauritia flexuosa for Iquitos. While the

  19. Análise microbiológica e bromatológica da água em bebedouros de escolas públicas em Belém do Brejo do Cruz-PB

    Directory of Open Access Journals (Sweden)

    Franklis B. F. Santana

    2015-08-01

    Full Text Available A água é um recurso essencial à sobrevivência de todos os seres vivos e o seu fornecimento em quantidade e qualidade é fundamental para a perfeita manutenção da vida humana. O presente trabalho teve como objetivo realizar a análise microbiológica e bromatológica da água em bebedouros de escolas públicas na cidade de Belém do Brejo do Cruz – PB. Para as análises físico-químicas foram coletadas 100 ml de cada amostra e distribuídas entre as seguintes análises: cor, turbidez e pH, enquanto para a análise microbiológica foi utilizada kit Colilert® (técnica de substrato cromogênio. Foi constatado que para a análise microbiológica as amostra E1, E3, E4 e E5 os resultados foram insatisfatório, pois a portaria vigente estabelece que para a água tratada não se admite a presença de coliformes totais e Escherichia coli em amostra de 100 ml. Para a amostra E2 foi observado resultado satisfatório, fator importante para o ambiente escolar. A amostra E6, não se aplica a análise em virtude da água não ser tratada, ou seja, trata-se de água de poço, caracterizando a mesma como imprópria. Quanto a análise físico-química, de amostras coletadas de bebedouros e caixa d’água pode-se observar que a conclusão dos resultados estão todos satisfatória de acordo com as normas estabelecidas pela Portaria 2.914/11 do Ministério da Saúde. Para que a água chegue às residências em boas condições, é necessário que a Estação de Tratamento da Água mantenha os reservatórios em boas condições para que não ocorram alterações na qualidade da água.

  20. Estudo soroepidemiológico da infecção pelo vírus da hepatite B entre portadores do vírus da imunodeficiência humana/sida na cidade de Belém, Pará - Brasil

    Directory of Open Access Journals (Sweden)

    Maria Rita de Cassia Costa Monteiro

    2004-01-01

    Full Text Available O objetivo desta pesquisa foi estudar a prevalência de infecção pelo virus da hepatite B em 406 portadores do virus da imunodeficiência humana, maiores de dezoito anos de idade, atendidos na rede pública de saúde da cidade de Belém, Pará, assim como analisar possíveis fatores de risco para a infecção. A prevalência global de infecção pelo virus da hepatite B foi de 51% (IC: 46,1 - 55,8, com 7,9% (IC: 5,3 - 10,5 para o HBsAg, 45,1% (IC: 40,3 - 49,9 para o anti-HBc e 32,3% (IC: 27,5 - 36,8 para o anti-HBs. Após ajuste por regressão logística, os marcadores sorológicos de infecção pelo vírus da hepatite B apresentaram associação com as seguintes variáveis: idade, situação conjugal e preferência sexual. A prevalência dos marcadores do vírus B nos heterossexuais foi 28,7% e 68,8% nos homossexuais/bissexuais (IC: 3,50 - 9,08; OR: 5,63; p=0,000. Quanto à situação conjugal, a categoria com companheiro fixo/casado apresentou freqüência de 31%, e foi de 58,7% a observada no grupo sem companheiro fixo (IC: 1,29 - 3,63; OR: 2,16; p=0,003. A análise multivariada não mostrou associação do vírus B com o uso de drogas ilícitas injetáveis.

  1. Expansion Formulation of General Relativity: the Gauge Functions for Energy-Momentum Tensor

    Science.gov (United States)

    Beloushko, Konstantin; Karbanovski, Valeri

    At present the one of the GR (General Relativity) basic problem remains a definition of the gravitation field (GF) energy. We shall analyze this content. As well known, the energy-momentum ``tensor'' (EMT) of GF was introduced by Einstein [1] with purpose of the SRT (Special Relativity Theory) generalization. It supposed also, that EMT of matter satisfy to the condition begin{equation} ⪉bel{GrindEQ__1_1_} T^{ik} _{;i} =0 (a semicolon denotes a covariant differentiation with respect to coordinates). In absence of GF the equation (ref{GrindEQ__1_1_}) reduces to a corresponding SRT expression begin{equation} ⪉bel{GrindEQ__1_2_} T^{ik} _{,i} =0 (a comma denotes a differentiation with respect to coordinates of space-time). Obviously, the ``conservation law'' (ref{GrindEQ__1_2_}) is not broken by transformation begin{equation} ⪉bel{GrindEQ__1_3_} T^{ik} to tilde{T}^{ik} =T^{ik} +h^{ikl} _{,l} , where for h(ikl) takes place a constrain begin{equation} ⪉bel{GrindEQ__1_4_} h^{ikl} =-h^{ilk} Later the given property has been used for a construction ``pseudo-tensor'' tau (ik) of ``pure'' GF [2, S 96] begin{equation} ⪉bel{GrindEQ__1_5_} -gleft(frac{c^{4} }{8pi G} left(R^{ik} -frac{1}{2} g^{ik} Rright)+tau ^{ik} right)=h^{ikl} _{,l} However such definition was a consequence of non-covariant transition from a reference system with condition g(ik) _{,l} =0 to an arbitrary frame. Therefore the Landau-Lifshitz pseudo-tensor has no physical contents and considered problem remains actual. ``The non-covariant character'' of GF energy was the reason for criticism of GR as Einstein's contemporaries [3, 4], as and during the subsequent period (see, for example, [5]). In [6] were analyzed the grounds of given problem, which are connected with a formulation indefiniteness of ``the conservation law'' in curved space-time. In [7] contends, that the gravitational energy in EMT can be separated only ``artificially'' by a choice of the certain coordinate system. In [8] is concluded

  2. The interRAI Acute Care instrument incorporated in an eHealth system for standardized and web-based geriatric assessment: strengths, weaknesses, opportunities and threats in the acute hospital setting

    Science.gov (United States)

    2013-01-01

    Background The interRAI Acute Care instrument is a multidimensional geriatric assessment system intended to determine a hospitalized older persons’ medical, psychosocial and functional capacity and needs. Its objective is to develop an overall plan for treatment and long-term follow-up based on a common set of standardized items that can be used in various care settings. A Belgian web-based software system (BelRAI-software) was developed to enable clinicians to interpret the output and to communicate the patients’ data across wards and care organizations. The purpose of the study is to evaluate the (dis)advantages of the implementation of the interRAI Acute Care instrument as a comprehensive geriatric assessment instrument in an acute hospital context. Methods In a cross-sectional multicenter study on four geriatric wards in three acute hospitals, trained clinical staff (nurses, occupational therapists, social workers, and geriatricians) assessed 410 inpatients in routine clinical practice. The BelRAI-system was evaluated by focus groups, observations, and questionnaires. The Strengths, Weaknesses, Opportunities and Threats were mapped (SWOT-analysis) and validated by the participants. Results The primary strengths of the BelRAI-system were a structured overview of the patients’ condition early after admission and the promotion of multidisciplinary assessment. Our study was a first attempt to transfer standardized data between home care organizations, nursing homes and hospitals and a way to centralize medical, allied health professionals and nursing data. With the BelRAI-software, privacy of data is guaranteed. Weaknesses are the time-consuming character of the process and the overlap with other assessment instruments or (electronic) registration forms. There is room for improving the user-friendliness and the efficiency of the software, which needs hospital-specific adaptations. Opportunities are a timely and systematic problem detection and continuity of

  3. ANTROPOGEOMORFOLOGIA DA BACIA HIDROGRÁFICA DO MURUTUCU: ABASTECIMENTO HÍDRICO, USO E OCUPAÇÃO EM BELÉM-PA

    Directory of Open Access Journals (Sweden)

    Antônio Carlos Ribeiro Araújo Júnior

    2015-09-01

    Full Text Available As Unidades de Proteção Integral estão divididasem Estação Ecológica, Reserva Biológica, Parque Nacional (ou Estadual ou Municipal, Monumento Natural e Refúgio de Vida Silvestre. A Área de Proteção Ambiental de Belém (APA Belém enquadra-se na categoria Parque Nacional e se deve, sobremaneira, ao fato desta abrigar a fonte de abastecimento de água de toda a Região Metropolitana de Belém (RMB, os lagos Bolonha e Água Preta, além de guardar um ambiente ameno e contemplativo com atrativos turísticos. Apesar de estar inserida na região amazônica, abundante em recursos hídricos, a cidade de Belém e sua região metropolitana, historicamente enfrentam dificuldades de captação, armazenamento e distribuição de água. A antropogeomorfologia considerando as consequências positivas e negativas da ação humana sobre o relevo ajuda a compreender como as formas e processos da Bacia Hidrográfica do Murutucu (BHM são condicionados para se entender holisticamente quais alterações foram empreendidas nos mananciais do Utinga na BHM tornando mais eficiente o abastecimento hídrico na RMB. As alterações processadas na forma dos lagos mostraram ser necessárias para aumentar seu volume de água e assim atender a demanda crescente da população da RMB denotando que a antropogeomorfologia é um importante instrumento de gestão ambiental.

  4. Adolescent Black Holes May be Hard to Find

    Science.gov (United States)

    Elvis, Martin; Chakravorty, Susmita

    2017-08-01

    Finding adolescent black holes that are growing rapidly from their seed masses is a major goal of the next generation of large observatories. We have examined how these early quasars may appear in terms of their broad emission lines (BELs) in the optical and ultraviolet. We find that below 10**6 Msol, the equivalent widths of the BELs drop precipitously. Moreover, if the BELs originate in clouds that form as the cool phase of a multi-phase medium, then for metallicities Z/Zsol ~> 3, so quasars are preferentially found in special environments, perhaps with deep potential wells. The population that we see though could be biased by the Z/Zsol > 3 requirement. A stronger argument is that the thermal instability leading to cool clouds is predominantly due to line emission by iron. Iron comes primarily from type 1a supernovae, which take of order 1 billion years to ignite. Hence iron should be under-abundant relative to other elements until z ~ 6 - 7. That the highest redshift quasar is at z = 7.1 may be a consequence of this requirement. Quasars above z ~ 7 could still be found by their rest-frame ultraviolet or X-ray continuum.

  5. NO-Releasing Enmein-Type Diterpenoid Derivatives with Selective Antiproliferative Activity and Effects on Apoptosis-Related Proteins

    Directory of Open Access Journals (Sweden)

    Dahong Li

    2016-09-01

    Full Text Available A series of nine enmein-type ent-kaurane diterpenoid and furoxan-based nitric oxide (NO donor hybrids (10a–i were designed and synthesized from commercially available oridonin (1. These hybrids were evaluated for their antiproliferative activity against Bel-7402, K562, MGC-803, and CaEs-17 human cancer cell lines and L-02 normal liver cells. The antiproliferative activity against tumor cells was stronger than the lead compound 1 and parent molecule 9 in most cases. Especially, compound 10f showed the strongest activity against human hepatocarcinoma Bel-7402 cell line with an IC50 of 0.81 μM and could also release 33.7 μmol/L NO at the time point of 60 min. Compounds 10a–i also showed cytotoxic selectivity between tumor and normal liver cells with IC50 ranging from 22.1 to 33.9 μM. Furthermore, the apoptotic properties on Bel-7402 cells revealed that 10f could induce S phase cell cycle arrest and apoptosis at low micromolar concentrations. The effects of 10f on apoptosis-related proteins were also investigated. The potent antiproliferative activities and mechanistic studies warrant further preclinical investigations.

  6. S pritselom na Belõi dom

    Index Scriptorium Estoniae

    2006-01-01

    USA vahevalimised andsid stardi presidendikandidaatide ülesseadmise kampaaniaks. Hillary Clinton kogus valimistel oma osariigis 70% häältest, mis teeb temast demokraatide kandidaatide hulgas liidri. Vabariiklaste kandidaadid presidendi kohale

  7. Seroprevalence of HIV, HTLV, CMV, HBV and rubella virus infections in pregnant adolescents who received care in the city of Belém, Pará, Northern Brazil.

    Science.gov (United States)

    Guerra, Aubaneide Batista; Siravenha, Leonardo Quintão; Laurentino, Rogério Valois; Feitosa, Rosimar Neris Martins; Azevedo, Vânia Nakauth; Vallinoto, Antonio Carlos Rosário; Ishak, Ricardo; Machado, Luiz Fernando Almeida

    2018-05-16

    Prenatal tests are important for prevention of vertical transmission of various infectious agents. The objective of this study was to describe the prevalence of human immunodeficiency virus (HIV), human T-lymphotropic virus (HTLV), hepatitis B virus (HBV), cytomegalovirus (CMV), rubella virus and vaccination coverage against HBV in pregnant adolescents who received care in the city of Belém, Pará, Brazil. A cross-sectional study was performed with 324 pregnant adolescents from 2009 to 2010. After the interview and blood collection, the patients were screened for antibodies and/or antigens against HIV-1/2, HTLV-1/2, CMV, rubella virus and HBV. The epidemiological variables were demonstrated using descriptive statistics with the G, χ 2 and Fisher exact tests. The mean age of the participants was 15.8 years, and the majority (65.4%) had less than 6 years of education. The mean age at first intercourse was 14.4 years, and 60.8% reported having a partner aged between 12 and 14 years. The prevalence of HIV infection was 0.3%, and of HTLV infection was 0.6%. Regarding HBV, 0.6% of the participants had acute infection, 9.9% had a previous infection, 16.7% had vaccine immunity and 72.8% were susceptible to infection. The presence of anti-HBs was greater in adolescent between 12 and 14 years old (28.8%) while the anti-HBc was greater in adolescent between 15 and 18 years old (10.3%). Most of the adolescents presented the IgG antibody to CMV (96.3%) and rubella (92.3%). None of the participants had acute rubella infection, and 2.2% had anti-CMV IgM. This study is the first report of the seroepidemiology of infectious agents in a population of pregnant adolescents in the Northern region of Brazil. Most of the adolescents had low levels of education, were susceptible to HBV infection and had IgG antibodies to CMV and rubella virus. The prevalence of HBV, HIV and HTLV was similar to that reported in other regions of Brazil. However, the presence of these agents in this

  8. Le règne de Louis XIV, ou la rupture définitive entre la société française et la monarchie

    OpenAIRE

    Bouveresse, Jacques

    2018-01-01

    Le règne de Louis XIV, comme Janus, présente deux faces. La première de ces faces qui correspond au vingt-cinq premières années du règne est brillante et lumineuse. Tout s’ordonne autour du roi dans un bel ordonnancement classique. Louis XIV est le maître de la guerre et de la paix. Il est entouré d’une cour brillante où il n’y a pas que des courtisans mais aussi beaucoup d’hommes capables et compétents. À partir des années 1680 – et à cet égard la révocation de l’Édit de Nantes en 1685 est u...

  9. Síndrome de Gianotti-Crosti: aspectos clínicos, laboratoriais e perfis sorológicos observados em 10 casos procedentes de Belém-PA (Brasil Gianotti-Crosti syndrome: clinical, laboratorial features, and serologic profiles of 10 cases from Belém, State of Para, Brazil

    Directory of Open Access Journals (Sweden)

    Daniela A. Lima

    2004-12-01

    Full Text Available FUNDAMENTOS: A síndrome de Gianotti-Crosti (SGC é uma doença rara e autolimitada caracterizada por erupção eritematopapulosa acrolocalizada e simétrica. Relaciona-se, na maioria das vezes, com infecção pelos vírus da hepatite B e Epstein-Barr, porém há poucas publicações relacionando a SGC com herpesvírus humano tipo 6 (HHV6. OBJETIVO: Estudar aspectos clínicos e laboratoriais e investigar a participação de patógenos virais na etiologia de casos de SGC procedentes de Belém-PA. PACIENTES E MÉTODOS: Dez crianças com diagnóstico clínico de SGC foram investigadas no período de agosto de 1996 a dezembro de 2002, utilizando-se provas laboratoriais de rotina e pesquisa de anticorpos séricos específicos para determinados vírus. O diagnóstico de SGC estabeleceu-se quando, além de aspectos clínicos considerados compatíveis, um ou mais dos seguintes critérios estavam presentes: elevação das enzimas hepáticas, linfocitose, positividade sorológica para um ou mais agentes virais ou história de vacinação prévia. RESULTADOS: Seis pacientes (60% apresentaram evidência de infecção primária pelo HHV6 demonstrada pela presença de anticorpos específicos da classe IgM. CONCLUSÃO: A detecção de anticorpos anti-HHV6 da classe IgM em seis dos pacientes apresentados sugere um possível papel etiológico desse vírus na doença, recomendando-se que seja acrescentado ao painel sorológico rotineiramente pesquisado em processos exantemáticos com morfologia sugestiva de SGC.BACKGROUND: Gianotti-Crosti syndrome (GCS is a rare, self-limited disease characterized by a symmetrical erythematopapulous, acral-based eruption. In most cases a definite relationship with a viral infection can be established, especially when hepatitis B or Epstein-Barr viruses are involved. However, few case reports on associations between GCS and human herpesvirus 6 (HHV6 have been published to date. OBJECTIVE: To study clinical and laboratorial aspects

  10. Observações sôbre a produtividade de seringueiras (Hevea brasiliensis muell.-arg. Plantadas de sementes: IV - Produtividade de 29 plantas existentes na travessa Itororó, Belém, Pá Observations on the latex production of seedlings of rubber trees (Hevea brasiliensis muell.-arg.: IV - Study of 29 rubber trees of the travessa Itororó, Belém, Pará

    Directory of Open Access Journals (Sweden)

    Luiz O. T. Mendes

    1960-01-01

    Full Text Available Neste trabalho são apresentados os resultados do estudo da produtividade de 29 seringueiras plantadas de sementes, existentes na Travessa Itororó, Belém, quando tinham a idade de 25 anos aproximadamente. Os resultados se referem à produção obtida de sangrias feitas a meia espiral, em dois regimes de trabalho: a em dias alternados, de 16 de setembro de 1943 a 31 de março de 1944; b todos os dias úteis, de 1.° de abril a 30 de setembro de 1944. Do conjunto de seringueiras estudadas os resultados mostram que a melhor planta logo após as primeiras sangrias já se classificara em primeiro lugar, quanto à produção. Os dados revelam também que houve pequena diminuição na produção média da população, ao passar para o regime de sangria diária; observou-se no entanto, que o decréscimo de produção foi mois pronunciado e freqüente entre as plantas de maior produtividade médio no regime de sangria em dias alternados. O estudo da população como um todo mostra que uma pequena parcela das plantas contribuiu com grande parte da produção; em ambos os regimes de trabalho, cerca de 25% da população de plantas foram responsáveis por aproximadamente 50% do produção de látex, e mais ou menos 50% da população de plantas produziram cerca de 75% da produção de látex. Tais resultados mostram a importância que se deve dar à eliminação precoce de plantas pouco produtivas, no caso de se fazerem plantações a partir de sementes não selecionadas.The results of 13 month tappings (half-spiral cut of 29 seedlings of rubber trees, approximately 25 years old, ore presented. From September 16, 1943 to March 31, 1944, the trees were tapped every other day; from Abril 1st, to September 30, 1944, every day. The change of the tapping system, from every other day to daily, caused a small decrease in the mean yield of the group, per tapping; this yield decrease was more pronounced and frequent in the high production plants. It must be

  11. COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

    International Nuclear Information System (INIS)

    Skliarov, V.; Rottger, A.; Honig, A.; Korostin, S.; Kuznetsov, S.; Lapenas, A.; Milevsky, V.; Ivaniukovich, A.; Kharitonov, I.; Sepman, S.

    2009-01-01

    According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5. meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. (authors)

  12. COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

    Energy Technology Data Exchange (ETDEWEB)

    Skliarov, V. [National Scientific Centre, Institute of Metrology (NSC IM), Kharkiv (Ukraine); Rottger, A.; Honig, A. [Physikalisch-Technische Bundesanstalt (PTB), Braunschweig (Germany); Korostin, S.; Kuznetsov, S. [All-Russian Scientific Research Institute of Physical, Technical and Radio Measurements (VNIIFTRI), Moscow Region, Mendeleyevo (Russian Federation); Lapenas, A. [Latvian National Metrology Centre Ltd, Radiation Metrology and Testing Centre (RMTC), Salaspils (Latvia); Milevsky, V.; Ivaniukovich, A. [Belarussian State Institute of Metrology (BelGIM), Minsk (Belarus); Kharitonov, I.; Sepman, S. [D I Mendeleyev Institute of metrology (VNIIM), Saint Petersburg (Russian Federation)

    2009-06-15

    According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5. meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. (authors)

  13. Bio Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry and biology laboratoriesThe Bio Engineering Laboratory (BeL) is theonly full spectrum biotechnology capability within the Department...

  14. REVISÃO HISTÓRICO-GEOGRÁFICA DA GESTÃO PÚBLICA SOBRE O SISTEMA DE ABASTECIMENTO HÍDRICO DE BELÉM-PA

    Directory of Open Access Journals (Sweden)

    Renata Tabosa

    2016-08-01

    En este artículo se presenta una revisión histórica-geográfica de la red de suministro de agua integrada del Municipio de Belém, comentando, en segundo lugar, sobre la situación en los otros municipios de la región metropolitana de Belém. A partir de la investigación bibliográfica y documental, acompañado de la investigación de campo con más elaboración cartográfica si objetiva un análisis comparativo de las diferentes formas de instituciones de gestión pública del agua en forma de visión histórica y geográfica. Al principio se discute la gestión de recursos y el servicio de suministro desde el punto de vista institucional presentando el territorio oficial de COSANPA y SAAEB en la capital del estado. Posteriormente, se centra específicamente en la oferta integrada de COSANPA, que, en el municipio de Belén, se reúne un territorio más pequeño, en términos de superficie, y mucho más densa en términos de población. Por último, en un tercer momento, se discute los problemas en el suministro de los recursos hídricos y revisar las posibilidades que se ofrecen desde el mapeo de este fenómeno. Se llega a la conclusión, sin embargo, que la fuerza impulsora y explicativa de los procesos institucionales está no sólo en el interés público, pero en la selectividad de espacio para actividades económicas. Palabras clave: Abastecimiento del Agua; Espacio Geográfico; Belém-PA.

  15. Design, Synthesis and Biological Evaluation of C(6-Modified Celastrol Derivatives as Potential Antitumor Agents

    Directory of Open Access Journals (Sweden)

    Kaiyong Tang

    2014-07-01

    Full Text Available New six C6-celastrol derivatives were designed, synthesized, and evaluated for their in vitro cytotoxic activities against nine human cancer cell lines (BGC-823, H4, Bel7402, H522, Colo 205, HepG2 and MDA-MB-468. The results showed that most of the compounds displayed potent inhibition against BGC823, H4, and Bel7402, with IC50s of 1.84–0.39 μM. The best compound NST001A was tested in an in vivo antitumor assay on nude mice bearing Colo 205 xenografts, and showed significant inhibition of tumor growth at low concentrations. Therefore, celastrol C-6 derivatives are potential drug candidates for treating cancer.

  16. Inhibitory effects of α-pinene on hepatoma carcinoma cell proliferation.

    Science.gov (United States)

    Chen, Wei-Qiang; Xu, Bin; Mao, Jian-Wen; Wei, Feng-Xiang; Li, Ming; Liu, Tao; Jin, Xiao-Bao; Zhang, Li-Rong

    2014-01-01

    Pine needle oil from crude extract of pine needles has anti-tumor effects, but the effective component is not known. In the present study, compounds from a steam distillation extract of pine needles were isolated and characterized. Alpha-pinene was identified as an active anti-proliferative compound on hepatoma carcinoma BEL-7402 cells using the MTT assay. Further experiments showed that α-pinene inhibited BEL-7402 cells by arresting cell growth in the G2/M phase of the cell cycle, downregulating Cdc25C mRNA and protein expression, and reducing cycle dependence on kinase 1(CDK1) activity. Taken together, these findings indicate that α-pinene may be useful as a potential anti-tumor drug.

  17. Avrupa Bilimetri Yaz Okulundan İzlenimler

    Directory of Open Access Journals (Sweden)

    Güleda Doğan

    2012-09-01

    Full Text Available Bu yazıda, 1-7 Temmuz 2012 tarihlerinde Belçika’nın Leuven şehrinde düzenlenen Avrupa Bilimetri Yaz Okulu’nda (ESSS - European Summer School for Scientometrics edinilen izlenimler aktarılmıştır. Avrupa Bilimetri Yaz Okulu, 2010 yılından beri Almanya, Belçika ve Avusturya ortaklığında, özellikle bibliyometri ve bilimetri alanında tanınmış kişilerin katkılarıyla sürdürülmektedir. Yaz Okulu’nun 2013 yılı eğitimi, 8-13 Eylül tarihlerinde Berlin’de yapılacaktır.

  18. Avrupa Bilimetri Yaz Okulundan İzlenimler

    OpenAIRE

    Güleda Doğan; Zehra Taşkın

    2012-01-01

    Bu yazıda, 1-7 Temmuz 2012 tarihlerinde Belçika’nın Leuven şehrinde düzenlenen Avrupa Bilimetri Yaz Okulu’nda (ESSS - European Summer School for Scientometrics) edinilen izlenimler aktarılmıştır. Avrupa Bilimetri Yaz Okulu, 2010 yılından beri Almanya, Belçika ve Avusturya ortaklığında, özellikle bibliyometri ve bilimetri alanında tanınmış kişilerin katkılarıyla sürdürülmektedir. Yaz Okulu’nun 2013 yılı eğitimi, 8-13 Eylül tarihlerinde Berlin’de yapılacaktır....

  19. “Tomar” e “Zona Monumental de Ajuda Belem”. Dois projectos de salvaguardia, dois casos de estudo

    Directory of Open Access Journals (Sweden)

    Isabel Maria Augusto de Sousa Rosa

    2008-12-01

    Full Text Available Prosseguindo os propósitos deste Il Seminário internacional “Conservazione del Património Arquitectónico e Urbano”, onde irão ser confrontadas as experiências realizadas em Itália e Portugal no âmbito da conservação do património arquitectónico e urbano, são apresentados dois casos de estudo, objectivando a salvaguarda dos centros históricos, realizados em duas cidades portuguesas - Tomar (Centro Histórico e Lisboa (Zona Monumental Ajuda-Belém. Os dois Planos então realizados – Tomar, em 1996, e zona monumental Ajuda-Belém, em 2004 – ambos recorrendo a suporte informático, evidenciam na “decalage” de 8 anos, a importância dos avanços tecnológicos e informáticos, patente no projecto mais recente (Zona Monumental Ajuda - Belém, quer na aquisição e processamento de dados, quer ainda na consulta dos mesmos, processos que se têm revelado valiosíssimos para a conservação e salvaguarda do património arquitectónico, urbano e ambiental desta zona da cidade de Lisboa.

  20. Domik Petra / Jüri Kuuskemaa

    Index Scriptorium Estoniae

    Kuuskemaa, Jüri, 1942-

    2006-01-01

    Kunstiajaloolane Jüri Kuuskemaa tutvustab Peeter I majamuuseumi Kadriorus. Maja ajaloost, sisustusest (mööbel, kunstiesemed). Keldriruumis eksponeeritud Salomon Zeltrechti ja tema abiliste poolt tehtud kivibüstidest

  1. Impact of health legislation on the sale of anorectics in a city in the Amazon region Impacto da legislação sanitária na comercialização de anorexígenos em uma cidade da Amazônia

    Directory of Open Access Journals (Sweden)

    Luana Valéria da Silva Castro

    2012-06-01

    Full Text Available OBJECTIVES: The International Narcotics Control Board released its 2005 annual report, highlighting the Brazil population as one of the largest consumers of anorectics. In Brazil, the National Health Surveillance Agency issued the resolution RDC 58/2007 in order to control the prescription and sale of such drugs. In Belém, the biggest city in the Brazilian Amazon region, this resolution came into force in 2008, leading to inspections of drugstores and magistral pharmacies. The aim of this work was to evaluate the consumption of psychotropic anorectic drugs and the impact of RDC 58/2007 on the prescription and dispensing of anorectics in drugstores and magistral pharmacies in Belém. METHODOLOGY: A retrospective quantitative and descriptive study was conducted of records from the Municipal Department of Health Surveillance of Belém, for 2005 to 2008. The differences in findings were regarded significant when p OBJETIVOS: O International Narcotics Control Board publicou em 2005 sua pesquisa anual que demonstrou que a população brasileira são um dos maiores consumidores de anorexígenos. No Brasil, a Agência Nacional de Vigilância Sanitária publicou a resolução RDC 58/2007 com o objetivo de controlar a prescrição e comercialização deste tipo de medicamento. Em Belém, a maior cidade da Amazônia brasileira, esta resolução entrou em vigor em 2008, levando à inspeções em drogarias e farmácias. Este trabalho propõe avaliar o consumo de psicotrópicos anorexígenos e o impacto da RDC 58/2007 na prescrição e dispensação de anorexígenos nas drogarias e farmácias magistrais de Belém. METODOLOGIA: foi realizado um estudo retrospectivo, quantitativo e descritivo, com dados coletados do Departamento de Vigilância Sanitária de Belém, de 2005 a 2008. Os dados foram considerados quando p < 0,05. RESULTADOS: Um total de 1.641 balanços foram analisados oriundos de drogarias e farmácias magistrais. Anfepramona foi o medicamento

  2. Märt Agu käib isa Mait Agu jälgedes / Heili Sibrits

    Index Scriptorium Estoniae

    Sibrits, Heili, 1977-

    2001-01-01

    Koreograafi ja tantsupedagoogi Mait Agu poeg Märt Agu on Eesti Tantsuagentuuri tantsija ja Pedagoogilise Instituudi tantsujuhtimise viimase kursuse üliõpilane, kes esineb revüüteatris "Bel-⁹tage"

  3. Eduard Tubina muuseum = The Eduard Tubin Museum

    Index Scriptorium Estoniae

    2012-01-01

    Eduard Tubina muuseumi ja ekspositsiooni kujundusest. Kogu mööbel ja vitriinkapid projekteeriti spetsiaalselt muuseumisse. Sisearhitektid Kärt Loopalu, Krista Thomson (OÜ Superellips), Liina Langemets, loetletud nende tehtud töid

  4. Side effects of rational dose iodine-131 therapy for metastatic well-differentiated thyroid carcinoma

    International Nuclear Information System (INIS)

    Van Nostrand, D.; Neutze, J.; Atkins, F.

    1986-01-01

    Benua, Leeper, and others (BEL) have advocated the estimation of radiation exposure to the blood to select a more rational maximum safe dose of radioiodine (dosimetry) to treat metastatic functioning well-differentiated thyroid carcinoma. After adopting the BEL dosimetry approach, we reviewed the immediate (during hospitalization) and intermediate (from discharge up to 3 mo) side effects after our initial 15 therapies in ten patients. The doses ranged from 51 mCi (1887 MBq) to 450 mCi (16.65 GBq). Immediate side effects were observed in 12/15 (80%), are described in detail, and were as follows: gastrointestinal 10/15, salivary 9/15, nonsalivary neck pain, swelling, etc. 2/15, pulmonary 0/15. Intermediate side effects were observed in 10/15 (67%), are described in detail, and were as follows: gastrointestinal 0/15, salivary 3/15, nonsalivary neck pain, swelling, etc. 3/15, nasal complaints 2/15, transient bone marrow suppression 9/10, pulmonary 0/15. No patient required blood transfusions or had complications secondary to reduced blood counts. All patient complaints resolved; however, several patients may have reduced baseline blood counts one year after therapy. No other long-term side effect has been noted but the mean follow-up has been only 15 mo. In our opinion, we have not observed any side effect to date which would contraindicate the continued use and evaluation of the BEL dosimetry approach

  5. Side effects of rational dose iodine-131 therapy for metastatic well-differentiated thyroid carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Van Nostrand, D.; Neutze, J.; Atkins, F.

    1986-10-01

    Benua, Leeper, and others (BEL) have advocated the estimation of radiation exposure to the blood to select a more rational maximum safe dose of radioiodine (dosimetry) to treat metastatic functioning well-differentiated thyroid carcinoma. After adopting the BEL dosimetry approach, we reviewed the immediate (during hospitalization) and intermediate (from discharge up to 3 mo) side effects after our initial 15 therapies in ten patients. The doses ranged from 51 mCi (1887 MBq) to 450 mCi (16.65 GBq). Immediate side effects were observed in 12/15 (80%), are described in detail, and were as follows: gastrointestinal 10/15, salivary 9/15, nonsalivary neck pain, swelling, etc. 2/15, pulmonary 0/15. Intermediate side effects were observed in 10/15 (67%), are described in detail, and were as follows: gastrointestinal 0/15, salivary 3/15, nonsalivary neck pain, swelling, etc. 3/15, nasal complaints 2/15, transient bone marrow suppression 9/10, pulmonary 0/15. No patient required blood transfusions or had complications secondary to reduced blood counts. All patient complaints resolved; however, several patients may have reduced baseline blood counts one year after therapy. No other long-term side effect has been noted but the mean follow-up has been only 15 mo. In our opinion, we have not observed any side effect to date which would contraindicate the continued use and evaluation of the BEL dosimetry approach.

  6. A 30 KW RF power amplifier for the RFQ accelerator (Paper No. CP 27)

    International Nuclear Information System (INIS)

    Luktuke, R.D.; Garud, A.N.; Murthy, P.N.K.; Sethi, R.C.

    1990-01-01

    A radio frequency quadrupole (RFQ) accelerator, to accelerate deuterons to an energy of 150 keV with beam current of 20 mA, has been designed and is under construction. This accelerator needs approximately 30 kW of RF power to generate the desired voltage of 55 kV on the electrodes, at a frequency of 45 MHz. The power amplifier is designed with four stages of RF amplification using vacuum tubes. The first two stages are built with the tubes 6146 and BEL 250 CX, to deliver about 100 watts power to the grid circuit of the pre driver. The pre driver (EIMAC 5 CX 1500 A) and the driver (BEL 4000 CX) give an output power of about 5kW, at the grid of the high power amplifier. All the four tubes operate in class A/AB mode. The high power amplifier has been designed and is being built around the BEL power tetrode tube CQK-50-2. The output from the high power amplifier is fed to the RFQ, via a matching network to tranform the plate impedance to 50 ohm loop impedeance at the RFQ. The paper presents the design aspects of the high power amplifier, matching network and the results obtained for the earlier stages. (author). 3 refs., 3 tabs., 2 figs

  7. Oral live attenuated human rotavirus vaccine (RotarixTM offers sustained high protection against severe G9P[8] rotavirus gastroenteritis during the first two years of life in Brazilian children

    Directory of Open Access Journals (Sweden)

    Maria Cleonice A Justino

    2012-11-01

    Full Text Available In a large Phase III trial conducted in 10 Latin American countries, the safety and efficacy of the live attenuated monovalent rotavirus vaccine RIX4414 was evaluated in 15,183 healthy infants followed up during the first two years of life. Belém was the only site in Brazil included in this multicentre trial. The study in Belém included a subset of 653 infants who were followed up until 24 months of age for protection against severe rotavirus gastroenteritis. These subjects were randomly assigned in a 1:1 ratio to receive two doses of vaccine (n = 328 or two doses of placebo (n = 325 at approximately two and four months of age. Of the 653 enrolled infants, 23 dropped out during the study period. For the combined two-year period, the efficacy of RIX4414 was 72.3% [95% confidence interval (CI 37.5-89.1%] against severe rotavirus-related gastroenteritis, reaching a protection rate of 81.8% (95% CI 36.4-96.6% against circulating wild-type G9 rotavirus strains. It is concluded that two doses of RIX4414 are highly efficacious against severe rotavirus gastroenteritis in Belém during the first two years of life and provide high protection against the worldwide emergence and spread of G9P[8] strains.

  8. Kordumatu ja eksklusiivne antiikmööbel

    Index Scriptorium Estoniae

    2008-01-01

    Tallinnas Pronksi t. 6 asuv salong Antique Exclusive pakub restaureeritud kujul antiikmööblit ning maale, lühtreid, lauahõbedat, vaase, pronksist skulptuure ja muud. Enamik mööblist on pärit Lääne-Euroopast, restaureerimine toimub Pärnus

  9. Effect of Gabapentin/Memantine on the Infantile Nystagmus Syndrome in the Zebrafish Model: Implications for the Therapy of Ocular Motor Diseases.

    Science.gov (United States)

    Bögli, Stefan Yu; Afthinos, Maresa; Huang, Melody Ying-Yu

    2017-06-01

    Infantile nystagmus syndrome (INS) is a disorder characterized by typical horizontal eye oscillations. Due to the uncertain etiology of INS, developing specific treatments remains difficult. Single reports demonstrated, on limited measures, alleviating effects of gabapentin and memantine. In the current study, we employed the zebrafish INS model belladonna (bel) to conduct an in-depth study of how gabapentin and memantine interventions alleviate INS signs, which may further restore visual conditions in affected subjects. Moreover, we described the influence of both medications on ocular motor functions in healthy zebrafish, evaluating possible iatrogenic effects. Ocular motor function and INS characteristics were assessed by eliciting optokinetic response, spontaneous nystagmus, and spontaneous saccades in light and in dark, in 5- to 6-day postfertilization bel larvae and heterozygous siblings. Single larvae were recorded before and after a 1-hour drug treatment (200 mM gabapentin/0.2 mM memantine). Both interventions significantly reduced nystagmus intensity (gabapentin: 59.98%, memantine: 39.59%). However, while the application of gabapentin affected all tested ocular motor functions, memantine specifically reduced nystagmus amplitude and intensity, and thus left controls completely unaffected. Finally, both drug treatments resulted in specific changes in nystagmus waveform and velocity. Our study provides deeper insight into gabapentin and memantine treatment effect in the zebrafish INS model. Moreover, this study should establish zebrafish as a pharmacologic animal model for treating nystagmus and ocular motor disease, serving as a basis for future large-scale drug screenings.

  10. An experimental study on the antitumor effect of 131I-17-AAG in vitro and in vivo.

    Science.gov (United States)

    Wenyong, Tu; Lu, Liu; Daozhen, Chen; Weidong, Yin; Ying, Huang

    2009-02-01

    To observe the antitumor effect of (131)I-17-allylamino-17-demethoxygeldanamycin ((131)I-17-AAG) in vitro/in vivo and explore its antitumor mechanism with a view to its potential therapeutic application. (131)I-17-AAG was prepared by the reaction of 17-AAG with Na [(131)I] in the presence of hydrogen peroxide. The effects of (131)17-AAG on cell growth inhibition and cell cycle distribution in vitro were studied in BEL-7402 cells lines. Following BEL-7402 tumor implantation by subcutaneous xenografts into nude mice, the reagents were injected through the tail vein, and the tumor volume was measured and analyzed. At the end of the experiment, tumor specimens were processed for histopathological analysis. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) was used to investigate apoptosis. The expression change of Akt2 was tested by Western-blot analysis. Methyl-thiazolyl-tetrazolium assay showed inhibition rates of 27.7 +/- 5.3%, 57.3 +/- 4.3%, and 63.7 +/- 3.1%, in Na(131)I group, 17-AAG group, and (131)I-17-AAG group, respectively. The inhibition rate in the (131)I-17-AAG group differed significantly between N(a131)I group and 17-AAG group (F = 229.49, P AAG group, and (131)I-17-AAG group, respectively. Following infusion for 32 days, the tumor volumes in the (131)I-17-AAG group were significantly smaller than those in the DMSO group (F = 24.18, P AAG inhibited the proliferation of tumor cells and induced apoptosis. The expression of Akt2 in (131)I-17-AAG was significantly lower than that in the DMSO group or (131)I group. (131)I-17-AAG can effectively inhibit the growth of BEL-7402 tumor cells in vitro and in vivo. (131)I-17-AAG is a promising agent for the treatment of BEL-7402 cell tumor.

  11. An experimental study on the antitumor effect of 131I-17-AAG in vitro and in vivo

    International Nuclear Information System (INIS)

    Tu Wenyong; Liu Lu; Chen Daozhen; Huang Ying; Yin Weidong

    2009-01-01

    The objective of this study was to observe the antitumor effect of 131 I-17-allylamino-17-demethoxygeldanamycin ( 131 I-17-AAG) in vitro/in vivo and explore its antitumor mechanism with a view to its potential therapeutic application. 131 I-17-AAG was prepared by the reaction of 17-AAG with Na [ 131 I] in the presence of hydrogen peroxide. The effects of 131 17-AAG on cell growth inhibition and cell cycle distribution in vitro were studied in BEL-7402 cells lines. Following BEL-7402 tumor implantation by subcutaneous xenografts into nude mice, the reagents were injected through the tail vein, and the tumor volume was measured and analyzed. At the end of the experiment, tumor specimens were processed for histopathological analysis. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) was used to investigate apoptosis. The expression change of Akt2 was tested by Western-blot analysis. Methyl-thiazolyl-tetrazolium assay showed inhibition rates of 27.7±5.3%, 57.3±4.3%, and 63.7±3.1%, in Na 131 I group, 17-AAG group, and 131 I-17-AAG group, respectively. The inhibition rate in the 131 I-17-AAG group differed significantly between Na 131 I group and 17-AAG group (F=229.49, P 131 I group, 17-AAG group, and 131 I-17-AAG group, respectively. Following infusion for 32 days, the tumor volumes in the 131 I-17-AAG group were significantly smaller than those in the DMSO group (F=24.18, P 131 I group (F=20.68, P 131 I-17-AAG inhibited the proliferation of tumor cells and induced apoptosis. The expression of Akt2 in 131 I-17-AAG was significantly lower than that in the DMSO group or 131 I group. 131 I-17-AAG can effectively inhibit the growth of BEL-7402 tumor cells in vitro and in vivo. 131 I-17-AAG is a promising agent for the treatment of BEL-7402 cell tumor. (author)

  12. Thermal wind model for the broad emission line region of quasars

    International Nuclear Information System (INIS)

    Weymann, R.J.; Scott, J.S.; Schiano, A.V.R.; Christiansen, W.A.

    1982-01-01

    Arguments are summarized for supposing that the clouds giving rise to the broad emission lines of QSOs are confined by the pressure of an expanding thermal gas and that a flux of relativistic particles with luminosity comparable to the photon luminosity streams through this gas. The resulting heating and momentum deposition produces a transonic thermal wind whose dynamical properties are calculated in detail. This wind accelerates and confines the emission line clouds, thereby producing the broad emission line (BEL) profiles. In a companion paper, the properties of the wind at much larger distances (approx.kpc) than the BEL region are used to explain the production of the broad absorption lines (BAL) observed in some QSOs. The same set of wind parameters can account for the properties of both the BEL and BAL regions, and this unification in the physical description of the BEL and BAL regions is one of the most important advantages of this model. A characteristic size of approx.1 pc for the QSO emission line region is one consequence of the model. This characteristic size is shown to depend upon luminosity in such a way that the ionization parameter is roughly constant over a wide range of luminosities. An X-ray luminosity due to thermal bremsstrahlung of approx.1%--10% of the optical luminosity is another consequence of the model. The trajectories of clouds under the combined influence of ram pressure acceleration and radiative acceleration are calculated. From these trajectories emission line profiles are also calculated, as well as the wind and cloud parameters yielding profiles in fair agreement with observed profiles explored. Opacity in the wind due to electron scattering displaces the line cores of optically thin lines to the blue. This is roughly compensated for by the redward skewing of optically thick lines due to preferential emission of photons from the back side of the clouds.void rapid depletion due to Compton losses are discussed

  13. Restoran Cha Dao = Restaurant Cha Dao

    Index Scriptorium Estoniae

    2012-01-01

    Tallinnas Suur-Patarei 2 asuva Hiina restorani Cha Dao sisekujundusest. Restorani mööbel, v.a toolid, projekteeriti eritellimusena. Sisearhitekt Dmitri Pisarenko (DM3 OÜ), loetletud tema töid. Arhitekt Meeli Truu

  14. Eesti Põlevkivi ajab taga hiigelrehve oma kalluritele / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2008-01-01

    Ilmunud ka: Põhjarannik 18. apr. 2008, lk. 1, Severnoje Poberezhje 18. apr. 2008, lk. 1. Eesti Põlevkivi kuulutas välja riigihanke 174 rehvi ostmiseks suurtele karjäärikalluritele Euclid ja BelAZ

  15. Modeling heat stress under different environmental conditions.

    Science.gov (United States)

    Carabaño, M J; Logar, B; Bormann, J; Minet, J; Vanrobays, M-L; Díaz, C; Tychon, B; Gengler, N; Hammami, H

    2016-05-01

    Renewed interest in heat stress effects on livestock productivity derives from climate change, which is expected to increase temperatures and the frequency of extreme weather events. This study aimed at evaluating the effect of temperature and humidity on milk production in highly selected dairy cattle populations across 3 European regions differing in climate and production systems to detect differences and similarities that can be used to optimize heat stress (HS) effect modeling. Milk, fat, and protein test day data from official milk recording for 1999 to 2010 in 4 Holstein populations located in the Walloon Region of Belgium (BEL), Luxembourg (LUX), Slovenia (SLO), and southern Spain (SPA) were merged with temperature and humidity data provided by the state meteorological agencies. After merging, the number of test day records/cows per trait ranged from 686,726/49,655 in SLO to 1,982,047/136,746 in BEL. Values for the daily average and maximum temperature-humidity index (THIavg and THImax) ranges for THIavg/THImax were largest in SLO (22-74/28-84) and shortest in SPA (39-76/46-83). Change point techniques were used to determine comfort thresholds, which differed across traits and climatic regions. Milk yield showed an inverted U-shaped pattern of response across the THI scale with a HS threshold around 73 THImax units. For fat and protein, thresholds were lower than for milk yield and were shifted around 6 THI units toward larger values in SPA compared with the other countries. Fat showed lower HS thresholds than protein traits in all countries. The traditional broken line model was compared with quadratic and cubic fits of the pattern of response in production to increasing heat loads. A cubic polynomial model allowing for individual variation in patterns of response and THIavg as heat load measure showed the best statistical features. Higher/lower producing animals showed less/more persistent production (quantity and quality) across the THI scale. The

  16. How global polity works: mobilizing political actors towards a joint agenda

    DEFF Research Database (Denmark)

    Milana, Marcella

    Conferences on Adult Education, organized every 12 years, since 1949. These conferences, funded by member states, gather representatives from governments, the academia, and other national and international entities, including non-governmental organizations, and represent a second level of political decision......Since World Word II the work by inter-states organizations created a shift in social imaginaries on the relation between education, work and the socio-economic development of nation-states (Milana 2012). These imaginaries materialized in a ‘global polity’ (Corry 2010), namely the mobilization...... International Conference on Adult Education, held in 2009 in Belèm (Brazil), under the auspicious of Unesco (hereafter Confintea VI). The Belèm Framework for Action lays out prescriptive activities to be implemented at either national or international levels, within five areas: adult literacy, learners...

  17. Utilization of whey

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    Compositions of wheys from cheesemaking and ultrafiltration are tabulated and some indications of the pollution potential and the cost of disposal of whey are given. The following treatments are described: ion exchange and electrodialysis for demineralization and deacidification; concentration by reverse osmosis, evaporation, spray drying, ''Hatmaker'' (roller) drying, and a drying technique using small Teflon balls; separation of proteins by ''Centri-Whey'' (Alfa-Laval) and ''Bel-Industrie'' heat/acid coagulation, ultrafiltration and other methods; purification and enzymic hydrolysis of lactose, and use of lactose as a substrate for protein biosynthesis by ''Bel'' (lactic acid yeast), ''Devos'' (Saccharomyces yeast) and ''Caliqua-Sireb'' (using fungi) processes. The use of whey for producing ethanol, lactic acid, vinegar, vitamins, antibiotics, enzymes and fats; and development of industrial whey processing in France are reviewed.

  18. Restoration of Gottseelige Schluess und Fuersaetz der Seele, an eighteenth century vellum bound book

    Directory of Open Access Journals (Sweden)

    Margit J. Smith

    2008-08-01

    Full Text Available L'article concerne la restauration d'un livre du XVIIIe siècle imprimé à Würzburg. Le travail a été réalisé dans le cadre d'un workshop au Centro del bel libro, à Ascona, en Suisse, sous la direction de Renate Mesmer. Pour préserver autant que possible le livre original, les techniques les moins invasives ont été appliquées afin de réparer le papier et la couverture, mais le livre a dû être recousu en totalité.The article concerns the complete restoration of an 18th century vellum bound book printed in Würzburg. All work was done during a workshop at the Centro del bel libro in Ascona, Switzerland, under the direction of Ms Renate Mesmer. To preserve as much as possible of the original book, the least invasive techniques were applied in repairing paper, vellum, and the endbands, but the bookblock had to be disbound and re-sewn completely. In a new method, the vacuum table was used to force the Yapp edges back to their original 90-degree. To repair a circular hole in the cover, the replacement vellum was skived on the hair-side in contrast to usually skiving on the flesh-side, using a glass shard in addition to the skiving knife.

  19. Sada ruutmeetrit luksust / Maris Kerge

    Index Scriptorium Estoniae

    Kerge, Maris

    2013-01-01

    Korter Kadriorus Weizenbergi tänaval arhitekt Karl Burmani 1928. a. projekteeritud korterelamus. Sisearhitektid Hanna Karits ja Annes Arro (Arro Projekt OÜ). Korteri kese on spaavannituba. Erimööbel on sisearhitektide kavandatud. Ehitusaeg: 2012

  20. Поступ слона и полёт орла сошлись на "Диком поле" / Борис Тух

    Index Scriptorium Estoniae

    Тух, Борис, 1946-

    2009-01-01

    Moskvas anti taas välja teineteisega konkureerivaid filmiauhindu "Kuldne Kotkas" ("Zolotoi Orjol") ja "Valge Elevant" ("Belõi Slon"). Seekord võitis mõlemad parima filmina Mihhail Kalatozišvili film "Metsik põld" ("Dikoje polje")

  1. Kööktuba Kadriorus / Ele Praks

    Index Scriptorium Estoniae

    Praks, Ele

    1999-01-01

    Kõigi mugavustega kööktoa (dolomiidist kamin, siin-seal katmata jäetud tellistest sein, sepistatud kardinapuud, nahkmööbel ning sinine köök) sisekujundus. Voodriga kardinad kavandas Ele Praks. 5 illustratsiooni

  2. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ASSOCIAZIONE MEDICI ENDOCRINOLOGI MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES - 2016 UPDATE

    DEFF Research Database (Denmark)

    Gharib, Hossein; Papini, Enrico; Garber, Jeffrey R

    2016-01-01

    by the American Association of Clinical Endocrinologists (AACE), American College of Endocrinology (ACE) and Associazione Medici Endocrinologi (AME). ABBREVIATIONS: AACE = American Association of Clinical Endocrinologists ACE = American College of Endocrinology AME = Associazione Medici Endocrinologi BEL = best...

  3. Elamise tornist fantaasiamaastikuni

    Index Scriptorium Estoniae

    2001-01-01

    Vitra Disainimuuseumi avanäitus taani disainer Verner Pantoni loomingust: ühes tükis täisplastist tooli looja, mööbel-skulptuurid, elukeskkonna mõtestamine, kolmemõõtmelise ruumi täielik ekspluateerimine

  4. A clash of gods – Conceptualising space in Daniel 1

    African Journals Online (AJOL)

    2014-02-25

    Feb 25, 2014 ... as an apocalyptical work that is filled with symbolic .... represents the cosmological balance that was created by. Yahweh when he ... Daniel, and his friends are given Babylonian names. ... Belshazzar: 'may Bel protect his life.'.

  5. Beyond Intellectual Property: Toward Traditional Resource Rights ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    That voice belongs to the world's indigenous peoples, and it is voice that has ... how indigenous peoples and local communities worldwide should approach ... National Council for Science and Technology at the Goeldi Museum, Belém, Brazil.

  6. Vannisalong Coral pakub kvaliteeti soodsa hinna eest

    Index Scriptorium Estoniae

    2007-01-01

    Tallinnas A. H. Tammsaare tee 116 ja Tartus Teguri 45 asuvas vannisalongis Coral pakutakse põhiliselt vanne ja saunu, kuid müügil on ka dušikabiinid, segistid, valamud, vannitoamööbel, basseinid jm

  7. Ocorrências da família Sarcophagidae (Insecta, Díptera em carcaças de Sus scrofa Linnaeus (Suidae em Belém-PA, colonização da carcaça e sua relação com o tempo de morte do animal

    Directory of Open Access Journals (Sweden)

    Paula Daniela Raiol Bitar de Araujo

    2013-10-01

    Full Text Available O presente trabalho visa verificar a ocorrência de Dípteros de interesse forense em uma carcaça de suíno, sua colonização e relação com o tempo de morte do animal, dando maior ênfase na família Sarcophagidae, por constituírem fauna constante e obrigatória de carcaça e por utilizarem esse substrato como sítio de procriação. O experimento foi realizado em uma área de mata, localizada nas dependências do Instituto de Pesquisa Museu Emílio Goeldi, em Belém-Pa. Foi utilizado como isca um suíno (Sus scrofa L. inteiro (com vísceras, de 14,5 Kg, recém abatido. Este foi exposto sob uma armadilha do tipo suspensa modificada, adequada à coletas de insetos adultos, sendo que também foram coletadas larvas e pupas, diretamente na carcaça. A ocorrência dos insetos adultos e de seus estágios larvais foi correlacionada com o tempo de morte do animal, a fim de possibilitar futuras inferências de tempo de morte com base na presença e dispersão destes insetos. O tempo de decomposição e a duração de cada estágio de decomposição foram registrados, tendo sido afetados provavelmente pelo tamanho da carcaça e pela estação do ano. Diferenças quanto ao padrão de sucessão não foram observadas

  8. Stratégies pour un vol virtuel : exemple de paysages brésiliens Estratégias para o voo virtual: exemplo de paisagens brasileiras Strategies for a virtual flight: the example of Brazilian landscapes

    Directory of Open Access Journals (Sweden)

    Alfredo Pereira de Queiroz Filho

    2011-03-01

    Full Text Available Ce travail aborde les deux principaux problèmes posés par le vol virtuel, l’orientation spatiale et la surcharge cognitive, et propose des stratégies qui facilitent la pratique de la navigation. Pour illustrer cette recherche, sont utilisés des exemples de paysages reconnus du territoire brésiliens, tels que Foz de Iguaçu (Paraná, Rio de Janeiro (État de Rio de Janeiro, Pantanal – (Mato Grosso du Sud, Salvador (Bahia, Belém (Pará, Manaus (Amazonas, et São Paulo (État de São Paulo.Este trabalho aborda os dois principais problemas do vôo virtual, a orientação espacial e a sobrecarga cognitiva, e propõe estratégias para auxiliar na sua navegação. Para ilustrar a pesquisa, são usados exemplos de consagradas paisagens do território brasileiro, como Foz do Iguaçu - PR, Rio de Janeiro - RJ, Pantanal - MS, Salvador - BA, Belém - PA, Manaus – MA e São Paulo – SP.This paper approaches the two main problems of the virtual flight, spatial orientation and cognitive overload, and proposes strategies to assist in its navigation. To illustrate the research, examples are used to dealing landscapes of the Brazilian territory, as Foz do Iguaçu - PR, Rio de Janeiro - RJ, Pantanal - MS, Salvador - BA, Belém - PA, Manaus - AM and São Paulo - SP

  9. Kumu Kunstimuuseum / Pekka Vapaavuori, Pia Sabelström, Pille Lausmäe

    Index Scriptorium Estoniae

    Vapaavuori, Pekka, 1962-

    2006-01-01

    II ja V korruse plaan, 2 välis- ja 5 sisevaadet; fotod: Kaido Haagen; projekteerija: Arkkitehtitoimisto Vapaavuori OY, 7 kaasautorit loetletud; sisekujundus: P. Sabelström; mööbel: P. Lausmäe, maastik: DIA Arhitektuur

  10. Põnevalt omalaadne salong igale maitsele

    Index Scriptorium Estoniae

    2008-01-01

    Sisustussalongis Antique & Repro pakutavast. Müügil on antiikmööbel (ka uusantiik), kaasaegsed õlimaalid, mis kopeerivad endisaegseid stiile ja originaalteoseid, sisustusesemed, Veneetsia lühtrid ja ehted. Salongist saab küsida nõu kodukujunduse osas

  11. Mart Sander ei tea oma saate tulevikku / Heili Sibrits

    Index Scriptorium Estoniae

    Sibrits, Heili, 1977-

    2002-01-01

    Muusikasaatest "Tähed muusikas". Mart Sanderi juhitav MTÜ Bel-Etage suurprojektidest 2002. aasta maist augustini: Sir Arthur Sullivani koomilisest ooperist "Trial by Jury" ("Vandekohus") ja Lionel Moncktoni muusikalist "The Arcadians" ("Arkaadlased"). Sander juhib BBC Eurovisioni-eelset saadet eesti muusikast

  12. THE PRODUCTION ORGANIZATION OF THE SAND SLUGS OF COLD-HARDENING MIXTURES AT ОАО “AZOVMASH”

    Directory of Open Access Journals (Sweden)

    A. P. Melnikov

    2005-01-01

    Full Text Available The experience of work of NP RUP “Institute BelNIIlit” with ОАО *'Azovmash” on assimilation of production of bars of the large steel castings founding for freight railway cars and cisterns is considered.

  13. Virmaliste valge kuma / Piret Veigel

    Index Scriptorium Estoniae

    Veigel, Piret, 1961-

    2004-01-01

    Kirsi ja Marko Ekströmi valge modernne ridaelamukorter (73 mø) Helsingis. Köögimööbel valmistati Eesti firmas Idema, projekti autor Peep Savason. Idemas tehti ka tualettruumi sisustus. K. Ekströmi kommentaarid. 13 ill

  14. Tekstiilikunstniku korter Kadrioru kohal / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2005-01-01

    Tekstiilikunstnik Elna Kaasiku korterist (88 mø) Kadrioru veerel asuva uue kortermaja viimasel korrusel. Parkettmööbel on tehtud E. Kaasiku jooniste järgi firmas Lahepuu. Projekt 2003, valmis 2005. Ill: korteri plaan, 11 värv. vaadet

  15. Seitse maailma parimat valitud / Nina Due ; interv. Urve Eslas

    Index Scriptorium Estoniae

    Due, Nina

    2008-01-01

    Londoni disainimuuseumi korraldatud maailma parima disainiobjekti võistlusest. Eestit esindas Fahle maja (KOKO Arhitektid). Loetletud võitjad seitsmes kategoorias: arhitektuur, graafika, transport, toode, mood, mööbel, interaktiivne. Näitus 2007. aasta sajast paremast disainiobjektist Londoni disainimuuseumis. 13 ill

  16. Netiportaal teadmata kadunud kunstiteoste leidmiseks / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2003-01-01

    Ameerika Muuseumide Assotsiatsiooni loodud veebileht The Nazi-Era Provenance Internet Portal (www.nenip.org) pakub ülevaadet Euroopast 1932.-1946. a. natside tegevuse tulemusena kaduma läinud kunstiteostest (maalid, margi- ja mündikollektsioonid, mööbel jm.)

  17. Juugendit armastav 21. sajandi kodu / Ene Vool

    Index Scriptorium Estoniae

    Vool, Ene, 1948-

    2006-01-01

    Kaunisse ümbrusse ehitatud stiilne maja, mille projekteeris Margit Kõrts. Sisustus, valgustid ja mööbel on juugendstiilis ja Kadri Tarbe-Pärtelpoeg projekteeris sobiva trepivõre ning trafarettmaalingu tegi Ruth Tuvike, kopeerides Alphonse Maria Mucha seinamaalingut. Mirjam Peili kommentaar

  18. Boligmarkedet under inflation

    DEFF Research Database (Denmark)

    Lunde, J.

    Rapportens enkelte kapitler behandler prisdannelsen på boligmarkedet, huslejereguleringen, prisudviklingen på bolig-delmarkederne, fremkomsten af kapital- og debitorgevinster ved besiddelse og belåning af boligejendomme, samt de samfundsøkonomiske årsager til denne prisudvikling og disse gevinstd...

  19. On the robust nonparametric regression estimation for a functional regressor

    OpenAIRE

    Azzedine , Nadjia; Laksaci , Ali; Ould-Saïd , Elias

    2009-01-01

    On the robust nonparametric regression estimation for a functional regressor correspondance: Corresponding author. (Ould-Said, Elias) (Azzedine, Nadjia) (Laksaci, Ali) (Ould-Said, Elias) Departement de Mathematiques--> , Univ. Djillali Liabes--> , BP 89--> , 22000 Sidi Bel Abbes--> - ALGERIA (Azzedine, Nadjia) Departement de Mathema...

  20. Restoran-apteek Londonis

    Index Scriptorium Estoniae

    1999-01-01

    Damien Hirsti kujundatud restoran Pharmacy Londonis, trendiinimeste lemmikkohti. Kahekorruselist maja täitev söögikoht on täis meditsiinilisi vihjeid. Haiglameeleolu hajutavad interjööris ja mööblikujunduses (mööbel Jasper Morrison) kasutatud soojad materjalid.

  1. Ausad asjad. Salong ZIZI

    Index Scriptorium Estoniae

    1998-01-01

    Sisustussalongist 'ZIZI' Vene t. 12 Tallinnas. Omanikud Viive Küttner, Priit Joala. Tekstiil ja puidust mööbel on salongiomanike oma firma toodang. Puidust eksponeerimismööbli on projekteerinud Priit Joala. Pakutava hulgas on disainer Tarmo Luisu (firma DAK) toodang

  2. On the inexplicability of the implicit: differences in the information provided by implicit and explicit tests

    NARCIS (Netherlands)

    DeCoster, J.; Banner, M.J.; Smith, E.R.; Semin, G.R.

    2006-01-01

    Implicit measures are often preferred to overt questioning in many areas of psychology. Their covert nature allows them to circumvent conscious expectations and biases, theoretically providing more objective indicators of people's true attitudes and bel iefs. However, we argue that implicit and

  3. Elementos doi: 10.5007/1807-9288.2011v7n1p167

    Directory of Open Access Journals (Sweden)

    Francisco Carlos de Carvalho Marinho

    2011-01-01

    Full Text Available Encerrando a presente edição da revista Texto Digital, apresentamos a belíssima criação "Elementos" do prof. Dr. Chico Marinho, da Universidade Federal de Minas Gerais (UFMG. Para ter acesso ao arquivo, clique aqui.

  4. Vineer & betoon / Henna Mäkiaho

    Index Scriptorium Estoniae

    Mäkiaho, Henna

    2007-01-01

    Taina Ketamo ja Ville Witka loft-stiilis kodu 1969. a. ehitatud lamekatusega majas (200 m2) Teijos. Mööbel on valmistatud oma kavandite järgi. Seinad ja laed on betoonist või kaetud vineeriga. Plaan, 9 värv. vaadet

  5. Fruit Flies of the Genus Anastrepha (Diptera: Tephritidae) From Some Localities of Paraguay: New Records, Checklist, and Illustrated Key

    Science.gov (United States)

    Arias, Osmar René; Fariña, Nelson Librado; Lopes, Gleidyane Novaes; Uramoto, Keiko; Zucchi, Roberto Antonio

    2014-01-01

    Abstract This study deals with fruit flies of the genus Anastrepha Schiner (Diptera: Tephritidae) collected in McPhail traps in the municipalities of Concepción, Belén, Horqueta, Loreto (state of Concepción) and Santa Rosa (state of Misiones), Paraguay. In total, 17 species were captured, 9 of which are new records for Paraguay. All morphological characters used for species identification are illustrated. RESUMEN. Se estudió las especies de moscas de las frutas del género Anastrepha Schiner (Diptera: Tephritidae), colectadas en trampas tipo McPhail en las localidades de Concepción, Belén, Horqueta (Departamento de Concepción) y Santa Rosa (Departamento de Misiones). En total fueron capturadas 17 especies, de las cuales nueve especies corresponden a nuevos registros para el Paraguay. Todos los caracteres morfológicos para la identificación de las especies fueron ilustrados. PMID:25525098

  6. Tallinna uus linnamööbel / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2007-01-01

    Tallinna uue linnamööbli saamise loost (ülevaade samas). Ebaõnnestunud "Tallinna Mooduli" konkursist. Linnadisainer Aavo Ermeli kavandatud linnamööblist, mille prototüübid tegi valmis Soome Firma Lassila & Tikanoja OYJ. A. Ermeli kommentaarid. 23 ill

  7. Estuarine and offshore fishing yield statistics and fishery policies in the state of Pará

    Directory of Open Access Journals (Sweden)

    Ivan Furtado Júnior

    2006-08-01

    Full Text Available The coast of Pará State extends for 562 km and it counts on 123 artisan-fishing communities, distributed along 17 coastal municipal districts. In this area of the State, it highlights the presence of growth of mangroves, streams, rivers and estuaries. All those factors that favor the fishing productivity hinder the systematic control of the landings a lot and with consequence in obtaining fishing production statistics. This work objective is to present the statistics of fishing production for species in landing volume, in the estuarine and marine areas of Pará Estate and to analyze the fishing police for the systems of industrial and artisan production in the period from 1997 to 2003. To esteem the fishing productions of the estuarine and marine areas in Pará State. There was monthly control on the boat in activity for type of fishing gear used and accomplished samples of the landings of each one of those combinations of boat fishing gear. In the studied area, the municipal districts that concentrate the largest landings are Belém, Bragança and Vigia. The tuna and billfish captures started having some importance from 2000 in Belém City and from 2002 in Belém city and municipal district of Curuçá. The species or groups of more important species in capture volume are yellow weakfish, Thomas sea catfish, Spanish mackerel, sharks, Caribbean red snapper, king weakfish, crab, marine catfish and shrimp and, in economic, value lobsters, shrimp and Caribbean red snapper.

  8. Effect of atomoxetine on quality of life and family burden: results from a randomized, placebo-controlled, double-blind study in children and adolescents with ADHD and comorbid oppositional defiant or conduct disorder.

    Science.gov (United States)

    Wehmeier, Peter M; Schacht, Alexander; Dittmann, Ralf W; Helsberg, Karin; Schneider-Fresenius, Christian; Lehmann, Martin; Bullinger, Monika; Ravens-Sieberer, Ulrike

    2011-06-01

    To evaluate the effect of atomoxetine on quality of life (QoL) and family burden in children and adolescents with attention deficit/hyperactivity disorder (ADHD) and comorbid oppositional defiant (ODD) or conduct disorder (CD). This secondary analysis was based on a randomized, double-blind, 9-week study of atomoxetine (target dose 1.2 mg/kg body weight) versus placebo. The study included 180 patients (atomoxetine 121, placebo 59), aged 6-17 years. QoL was measured using the KINDL-R questionnaire. The total score encompasses six dimensions (or subscales) measuring QoL in terms of "physical well-being", "emotional well-being", "self-esteem", "friends", "family", and "school". Family burden of illness was measured using the FaBel questionnaire. With atomoxetine, the KINDL-R total score improved significantly (P = 0.021) more than with placebo. This improvement also applied to the subscales except for "physical well-being" (opposite effect) and "school" (no effect). No significant treatment group differences were seen on the FaBel questionnaire. No differences were found between the fast and slow titration groups in terms of ADHD, ODD, and disruptive behavior severity. Furthermore, no such differences were observed for QoL and family burden. This study suggests positive effects of atomoxetine on quality of life, as measured by the KINDL-R scores on emotional well-being, self-esteem, friends and family, in children and adolescents with ADHD and comorbid ODD/CD. No significant treatment effects were seen on family burden, as measured by FaBel total score.

  9. Peidetud köögid / Ketlin Priilinn

    Index Scriptorium Estoniae

    Priilinn, Ketlin, 1982-

    2006-01-01

    Kabinetti suletud köök Tivali (Dante Bonuccelli), köök K11 (Norbert Wangen), köögimööbel Modus (Paola Nava, Fabio Casiraghi), köök Pantos Chef (Antonia Astor), köök Single (AlbertoColonello)

  10. Kargelt kosmilised vineerivõnked / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2011-01-01

    Näitus ""Veneer MG" - Maile Grünbergi poolt kujundatud mööbel painutatud kasevineerist" Tallinnas Arhitektuuri- ja Didainigaleriis. Kaubamärk "Veneer MG" sündis ettevõtte Aja Nägu OÜ ja didainer Maile Grünbergi koostöös

  11. Ergonomics SA - Vol 25, No 1 (2013)

    African Journals Online (AJOL)

    The effects of different types of cognitive tasks in conjunction with circadian regulation on heart rate variability and performance parameters · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. KC Huysamen, M Göbel, J Davy, 52-67 ...

  12. Koduse köögiga ridamaja / Shanti Broeng, Pernille Vest

    Index Scriptorium Estoniae

    Broeng, Shanti

    2004-01-01

    Kujundusgraafik Kathy Hertzi ja tema neljaliikmelise pere kodu Taanis Lundtofte linnas ridaelamus. Remondi käigus koliti köök elutuppa, endise köögi asemel on ateljee. Mööbel on segu kaasaegsest disainist, vanadest esemetest ja Kathy omaloomingust. 10 ill

  13. Mental health trajectories from childhood to young adulthood affect the educational and employment status of young adults : results from the TRAILS study

    NARCIS (Netherlands)

    Veldman, Karin; Reijneveld, Sijmen A.; Almansa, Josue; Verhulst, Frank C.; Bultmann, Ute

    Background Young adults at work without basic educational level (BEL), and young adults in Neither Employment, Education nor Training (NEET) are at high risk of adverse employment outcomes. Evidence lacks on the impact of mental health problems during childhood, adolescence and young adulthood on

  14. HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange

    DEFF Research Database (Denmark)

    Andersen, Ann-Dorit; Poulsen, Kristian Arild; Lambert, Ian H

    2009-01-01

    activation were reduced after acidic compared with neutral SI, whereas necrotic death, estimated as glucose-6-phosphate dehydrogenase release, was similar in the two conditions. Inhibition of iPLA(2)-VI activity by bromoenol lactone (BEL) elicited cardiomyocyte necrosis during normoxia and after acidic, yet...

  15. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    https://www.ias.ac.in/article/fulltext/reso/012/05/0021-0030. Keywords. van 't Hoff – biography; chemistry in space; stereochemistry; chemical dynamics; Stassfurt salt deposits; osmotic pressure–theory; Le Bel. Author Affiliations. G Nagendrappa1. # 13, Basappa Layout, Gavipuram Extension, Bangalore 560 019, India.

  16. Megakorter metropolis / Lara Sargent

    Index Scriptorium Estoniae

    Sargent, Lara

    2008-01-01

    Miljonärist kunstikollektsionääri viiel korrusel paiknev kodu New Yorgis. Juurde ehitati kümnes korrus. Katusekorter on mõeldud kaasaegse kunsti kollektsiooni eksponeerimiseks. Korteri kavandas itaalia arhitekt Andrea Ballerini. Köögimööbel tehti eritellimusel. 12 värv. vaadet

  17. Aet Piel : oluline sisekujunduselement on viltune sein / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Poolkaares ehitatud korterelamus on Aet Pieli kujundatud korteris üks sein viltu. Esmapilgul häirivana mõjunud sein sai oluliseks sisekujunduselemendiks. Eritellimusel valmistatud mööbel on tammepuidust. A. Pieli kommentaarid. Ill.: plaan enne ja nüüd, 9 värv. vaadet

  18. TLÜ Balti Filmi- ja Meediakool = University of Tallinn Baltic Film and Media School / Ville Lausmäe

    Index Scriptorium Estoniae

    Lausmäe, Ville, 1981-

    2013-01-01

    Eesti Sisearhitektide Liidu 2012. aasta parima avaliku ruumi preemia pälvinud Balti Filmi- ja Meediakooli hoone sisearhitektuursest lahendusest ja ruumikujundusest. Autorid: Kadi Karmann, Ville Lausmäe. Mööbel: Ville Lausmäe, Tõnis Kalve. Arhitektuur: Salto Arhitektid. Disaineri ja TLÜ dotsendi Krista Areni arvamus

  19. Novel 5-Fluorouracil Derivatives: Synthesis and Cytotoxic Activity of 2-Butoxy-4-Substituted 5-Fluoropyrimidines

    International Nuclear Information System (INIS)

    Sun, Jian; Zhou, Wei; Hu, Weixiao; Shan, Shang; Zhang, Shijie; Li, Haibo

    2013-01-01

    Twenty two new 5-fluorouracil (5-FU) derivatives, 2-butoxy-4-substituted 5-fluoropyrimidines, were synthesized and characterized by IR, 1 H NMR, MS, HRMS. All compounds were preliminarily evaluated by MTT assay on human liver BEL-7402 cancer cell line in vitro. Ten compounds were selected to test their cytotoxic activity against A549, HL-60 and MCF-7 cancer cell lines in vitro. These compounds were more sensitive to BEL-7402 than other cell lines, particularly, cytotoxic activity of compounds 6b, 6d-f, 6p, 6s-u were in sub-micromolar scale. The highest cytotoxic potency against A549, HL-60 and MCF-7 was shown by 2-butoxy-4-chloro-5-fluoropyrimidine (5) with IC 50 values of 0.10, 1.66 and 0.59 μM, respectively. Compounds 6d and 6e were effective against MCF-7 with IC 50 9.73 μM and HL-60 with IC 50 8.83 μM, respectively

  20. Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis

    Directory of Open Access Journals (Sweden)

    Afroza Khanam Irin

    2015-01-01

    Full Text Available Neurodegenerative as well as autoimmune diseases have unclear aetiologies, but an increasing number of evidences report for a combination of genetic and epigenetic alterations that predispose for the development of disease. This review examines the major milestones in epigenetics research in the context of diseases and various computational approaches developed in the last decades to unravel new epigenetic modifications. However, there are limited studies that systematically link genetic and epigenetic alterations of DNA to the aetiology of diseases. In this work, we demonstrate how disease-related epigenetic knowledge can be systematically captured and integrated with heterogeneous information into a functional context using Biological Expression Language (BEL. This novel methodology, based on BEL, enables us to integrate epigenetic modifications such as DNA methylation or acetylation of histones into a specific disease network. As an example, we depict the integration of epigenetic and genetic factors in a functional context specific to Parkinson’s disease (PD and Multiple Sclerosis (MS.

  1. Rastros de um rio urbano: cidade comunicada, cidade percebida Traces of an urban river: communicated city, perceived city

    Directory of Open Access Journals (Sweden)

    Fábio Duarte

    2006-12-01

    Full Text Available A análise do modo como as pessoas vivenciam a cidade e como regiões fazem parte do imagin��rio urbano é uma das questões mais importantes para o sucesso de um projeto de intervenção urbana. Neste artigo, apresentamos uma metodologia para a análise de como um ambiente está presente e é construído no imaginário urbano, tomando como estudo de caso o rio Belém, na cidade de Curitiba.The analysis of how people live in the city and how some regions are integrated into the urban imagination is one of the most important issues to the success of any project of urban intervention. In this article we propose a methodology to analyze how a specific environment is perceived and built in the urban imagination, taking the Belém river in Curitiba, as a case study.

  2. Structural Composition of Protozooplankton Communities in Relation to Environmental Factors in Shallow Lakes and Reservoirs of Rīga, Latvia

    Directory of Open Access Journals (Sweden)

    Buholce Linda

    2015-08-01

    Full Text Available Protozooplankton are dominant grazers of phytoplankton and an important component of the microbial food web, as a link between pico and nanoplankton to higher trophic levels. Their fast growing rate, relative abundance, biomass and diversity are used as indicators of organic and toxic pollution. The impact of urbanisation on ecosystems and their sustainability and biodiversity have recently been much studied. We studied the protozooplankton ciliate communities during the vegetation period from April to October in two small lakes (Bābelītis, Gaiļezers and two reservoirs (Bolderāja, Saurieši. The largest peak of biomass (15.7 × 102 mg/l was found in Gaiļezers Lake in August and of abundance (60.2 × 103 org/l in Bābelītis Lake in July. The lowest biomass (0.006 mg/l and abundance (0.12 × 103 org/l were found in the Saurieši Reservoir station. The most abundant ciliates were from the order Oligotrichida.

  3. A natureza da urbanizacão na Amazonia e sua expressão metropolitana

    Directory of Open Access Journals (Sweden)

    Saint-Clair Cordeiro da Trindade Junior

    2000-01-01

    Full Text Available Este artigo analisa a organização interna do espaçometropolitano de Belém (PA como uma expressãodas condições de desenvolvimento impostas à Amazônia e ao seu processo interno de regionalização.Diferentemente de outras regiões, em que a desconcentração metropolitana acompanha de perto ummovimento ligado a um certo dinamismo econômico, o processo de metropolização de Belém reflete,acima de tudo, as condições de pobreza que caracterizam a mão-de-obra disponível no espaço amazô-nico. Com base nessa reflexão, discute-se, então, deque maneira o processo de produção do espaço regional traz implicações decisivas para a organizaçãointra-urbana da metrópole belenense.

  4. Utilization of whey

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    Compositions of wheys from cheesemaking and ultrafiltration are tabulated and some indications of the pollution potential and the cost of disposal of whey are given. The following treatments are described: ion exchange and electrodialysis for demineralization and deacidification; concentration by reverse osmosis, evaporation, spray drying, ''Hatmaker'' (roller) drying, and a drying technique using small Teflon balls; separation of proteins by ''Centri-Whey'' (Alfa-Laval) and ''Bel-Industrie'' heat/acid coagulation, ultrafiltration and other methods; purification and enzymic hydrolysis of lactose, and use of lactose as a substrate for protein biosynthesis by ''Bel'' (lactic acid yeast), ''Devos'' (Saccharomyces yeast) and ''Caliqua-Sireb'' (using fungi) processes. The use of whey for producing ethanol, lactic acid, vinegar, vitamins, antibiotics, enzymes and fats; and development of industrial whey processing in France are reviewed.

  5. Mental health from a life-course perspective : The transition from school to work

    NARCIS (Netherlands)

    Veldman, Karin

    2016-01-01

    Adolescents suffering from mental health problems are at risk of dropping out from high school without a basic educational level (BEL) or to be in NEET (Neither in Education, Employment nor Training), and when having entered the labor market in adulthood, to be unemployed and earn lower wages. This

  6. Alvar Aalto - 100 / Leila Pärtelpoeg

    Index Scriptorium Estoniae

    Pärtelpoeg, Leila, 1927-

    1998-01-01

    Villa Mairea'st, mis valmis 1939. a. ja mille A. Aalto projekteeris oma mõttekaaslastele ja sõpradele Harry ja Maire Gullichsenidele. Loetletud A. Aalto juubelit tähistavad rahvusvahelised näitused. Tallinna Kunstihoone galeriis 10.-11. 03 1998 näitus "Aalto mööbel"

  7. The Responses of Tenth-Grade Students to Four Novels.

    Science.gov (United States)

    Grindstaff, Faye Louise

    To compare structural analysis with experiential reflective analysis as teaching techniques for literature, a study was made of the written responses of three groups of typical 10th-graders after reading four modern novels--Paul Annixter's "Swiftwater," Ray Bradbury's "Fahrenheit 451," Bel Kaufman's "Up the Down Staircase," and John…

  8. Smartphone en sikkel

    NARCIS (Netherlands)

    Popma, J.

    2013-01-01

    Zoals het in de negentiende eeuw vakbondsonderzoeken waren die de schrijnende arbeidsomstandigheden in fabrieken aan het licht brachten en de bonden halverwege de vorige eeuw als eersten aan de bel trokken over de gevaren van asbest, zo is het de vakbeweging die anno nu als eerste aandacht vraagt

  9. Etnicitet og udsathed

    DEFF Research Database (Denmark)

    Tireli, Üzeyir

    2015-01-01

    Kapitlet beskæftiger sig med relationen mellem udsathed og etnicitet og bearbejder spørgsmålet om, hvorfor nogle grupper defineres som udsatte, uden et egentligt empirisk belæg for kausalitetsforhold mellem etnicitet og udsathed. Desuden gives en forklaring på forskellighed i udsathed grupperne i...

  10. Loch Ness, Yeti og læringsstile

    DEFF Research Database (Denmark)

    Johansen, Martin Blok; Oksbjerg, Marianne

    2013-01-01

    Analyse og diskussion af læringsstilsbegrebet, som det fremstilles af Dunn og Dunn. I artiklen argumenteres der for, at der ikke er noget videnskabeligt belæg for at bringe læringsstile ind i klasseværelset. Det er alene en tros- og følelsessag....

  11. Economic Well-Being and Poverty Among the Elderly : An Analysis Based on a Collective Consumption Model

    NARCIS (Netherlands)

    Cherchye, L.J.H.; de Rock, B.; Vermeulen, F.M.P.

    2008-01-01

    We apply the collective consumption model of Browning, Chiappori and Lew- bel (2006) to analyse economic well-being and poverty among the elderly. The model focuses on individual preferences, a consumption technology that captures the economies of scale of living in a couple, and a sharing rule that

  12. Multicultural Choral Music Pedagogy Based on the Facets Model

    Science.gov (United States)

    Yoo, Hyesoo

    2017-01-01

    Multicultural choral music has distinct characteristics in that indigenous folk elements are frequently incorporated into a Western European tonal system. Because of this, multicultural choral music is often taught using Western styles (e.g., "bel canto") rather than through traditional singing techniques from their cultures of origin.…

  13. PRÁTICAS ESPACIAIS E USOS NOS ESPAÇOS PÚBLICOS DAS PRAÇAS EM CAPITAIS DA AMAZÔNIA ORIENTAL BRASILEIRA: OS CASOS DE BELÉM E MACAPÁ

    Directory of Open Access Journals (Sweden)

    Olavo Fagundes da Silva

    2016-12-01

    Full Text Available As cidades da Amazônia brasileira e mais especificamente duas capitais de sua porção oriental, Belém e Macapá, compartilham das mesmas águas da grande foz do Amazonas, mas também de novas dinâmicas espaciais urbanas. Este trabalho teve como objetivo analisar, avaliar e caracterizar as práticas espaciais em três praças na cidade de Belém e três praças na cidade de Macapá. Objetivou ainda, apontar elementos de estudo que pudessem servir como suporte à decisão no planejamento e desenvolvimento de políticas voltadas para a melhoria desses espaços públicos. A partir do estudo de três praças na cidade de Belém-PA e três na cidade de Macapá-AP, este trabalho avaliou a frequência de visitação e os usos desses espaços públicos no cotidiano. A coleta de dados e informações foi realizada a partir da abordagem de 102 frequentadores e através de registro fotográfico e de informações que denotassem os usos das praças. O trabalho resultou numa avaliação da frequência de visitação e tipificação dos usos dos lugares pesquisados, apontando práticas espaciais preponderantemente dominadas por atividades e grupos específicos. Esses grupos organizados reúnem-se quase sempre em determinados horários e dias da semana e ratificam forte comprometimento com os espaços públicos nas cidades alvo do estudo

  14. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 4. A Rebel in the Ranks: A Phosphonium Cation with a Planar Tetracoordinate Phosphorus Atom – An Anti van't Hoff-Le Bel ... Author Affiliations. V Chandrasekhar1. Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India.

  15. Cryogenic Research and Development

    Science.gov (United States)

    1960-09-30

    of right angle illumination (with respect to the camera ) may be illustrated from the fact that the scattering of light from a hydrogen bubble is 10...und Kondensierter Gase bel tiefen Temperaturen, A. Eucken, Verb. deut. Phys. Gesells . 18, 4 (1916) 27. Resonance method of measuring the ratio of the

  16. IDRC in Brazil

    International Development Research Centre (IDRC) Digital Library (Canada)

    Subscribe to the IDRC Bulletin: www.idrc.ca/idrcbulletin. BRAZIL. Macapá. Manaus. São Paulo. Belém. Fortaleza. Recife. Salvador. Rio de Janeiro. Porto. Alegre. Brasilia. ✪. ○. ○. ○. ○. ○. ○. ○. ○. ○. BOLIVIA. PERU. ECUADOR. COLOMBIA. VENEZUELA. CHILE. PARAGUAY. Atlantic Ocean. Pacific Ocean.

  17. Intellectual Capital

    DEFF Research Database (Denmark)

    Krebs, Anne

    2017-01-01

    Økonomistyring er ledelse udført på grundlag af økonomistyringssystemers billeder af forretningsenhedens omkostninger og udgifter set i relation til de budgetterede beløb. Billederne er et udtryk for økonomisk tænkning omsat til operationelle systemværktøjer. Mange fagprofessionelle indenfor lede...

  18. Disain kõrvuti Pärdi ja Oksasega Eestit esindamas / Monika Järg

    Index Scriptorium Estoniae

    Järg, Monika, 1975-

    2010-01-01

    Normandias festivalil "Les Boréales" 12.11.-31.12.2010 avatud eesti disaini näitusest "design_estonia", kus on eksponeeritud mööbel, valgustid ja tekstiilikunst. Projekti kuraatorid Marko Ala ja Ilona Gurjanova. Loetletud osalejaid. Põhja- ja Baltimaade kultuuri tutvustaval festivalil on veel esindatud muusika, kino ja kirjandus

  19. Response of Gliricidia sepium tree to phosphorus application and ...

    African Journals Online (AJOL)

    A pot experiment was carried out in a green house at Bel Air station to determine effect of phosphorus on the growth of Gliricidia sepium in presence of rhizobial strains and an arbuscular mycorrhiza fungus. A factorial 3 factors block was designed with arbuscular mycorrhizal fungus Glomus aggregatum, phophorus ...

  20. Eesti disainipreemiad 2009

    Index Scriptorium Estoniae

    2009-01-01

    Eesti Disainerite Liidu algatatud konkursil "Eesti disain ja elukeskond 2009" laekus disaini rubriigis 22 tööd, I preemia sai Margus Triibmanni, Tarmo Luisu ja Ville Jehe loodud moodulrattahoidja "Rohi", II preemia Jaanus Orgusaare vurr-tool "Kiirendi", III preemia Pavel Sidorenko ja Heiki Musta mitmeotstarbeline lastemööbel "Smart kid"

  1. Bad management

    DEFF Research Database (Denmark)

    Mac, Anita

    Burn Out (udbrændthed) beskrives i organisationslitteraturen som et individuelt fænomen, der viser sig som følge af ubalance mellem indsats og belønning i arbejdsmæssige relationer. Burn out er karakteriseret ved reaktionsformer, der indebærer depersonalisering og tilbagetrækning fra sociale rela...

  2. The Decibel Report: Acoustic Sound Measurement Modeling and the Effects of Sonar on Marine Mammals

    Science.gov (United States)

    2010-06-21

    sponsored by the U.S. Navy. The first of these was an intergovernmental conference hosted by the National Undersea Research Center (NURC) in La Specia...1989). 33. I. M. Mills, B. N. Taylor, and A. J. Thor, "Definitions of Units: Radian, Neper, Bel, and Decibel, Metrologia , vol. 38, pp. 353 - 361, 2001

  3. Investigating the Effect of Learning Styles in a Blended E-Learning System: An Extension of the Technology Acceptance Model (TAM)

    Science.gov (United States)

    Al-Azawei, Ahmed; Parslow, Patrick; Lundqvist, Karsten

    2017-01-01

    This study assesses learner perceptions of a blended e-learning system (BELS) and the feasibility of accommodating educational hypermedia systems (EHSs) according to learning styles using a modified version of the technology acceptance model (TAM). Recently, Moodle has been adopted by an Iraqi university alongside face-to-face (F2F) classrooms to…

  4. First record of Anastrepha serpentina (Wiedemann) (Diptera: Tephritidae) in citrus in Brazil.

    Science.gov (United States)

    Lemos, W P; da Silva, R A; Araújo, S C A; Oliveira, E L A; da Silva, W R

    2011-01-01

    Anastrepha serpentina (Wiedemann) is recorded for the first time in citrus (Rutaceae) in Brazil. Specimens were obtained from sweet orange (Citrus sinensis) sampled in the municipalities of Belém and Capitão Poço, and from mandarin orange (Citrus reticulata) from Tomé-Açu, state of Pará, Brazil.

  5. First record of Anastrepha serpentina (Wiedemann) (Diptera: Tephritidae) in citrus in Brazil

    OpenAIRE

    Lemos, WP; Silva, RA da; Araújo, SCA; Oliveira, ELA; Silva, WR da

    2011-01-01

    Anastrepha serpentina (Wiedemann) is recorded for the first time in citrus (Rutaceae) in Brazil. Specimens were obtained from sweet orange (Citrus sinensis) sampled in the municipalities of Belém and Capitão Poço, and from mandarin orange (Citrus reticulata) from Tomé-Açu, state of Pará, Brazil.

  6. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    U R Rao1. Chairman, PRl Council, Department of Space, Government of India, Antariksh Bhavan, New BEL Road, Bangalore 560 094, India. Resonance – Journal of Science Education. Current Issue : Vol. 23, Issue 4. Current Issue Volume 23 | Issue 4. April 2018. Home · Volumes & Issues · Categories · Special Issues ...

  7. Die Rolle des Gerichtsdolmetschers - Experte oder notwendiges Übel?

    DEFF Research Database (Denmark)

    Christensen, Tina Paulsen

    2012-01-01

    Die Zahl der gedolmetschten Gerichtsverhandlungen steigt weiterhin in vielen Rechtssystemen, weshalb es immer wichtiger wird, dass Rechtssysteme über qualifizierte Dolmetscher verfügen. In Dänemark begegnen Richter, die Rezipienten von Gerichtsdolmetschleistungen sind, sowohl professionellen als...... auch nicht- oder semi-professionellen Gerichtsdolmetschern. Dies lässt vermuten, dass die Richter in der Praxis Dolmetschleistungen von sehr unterschiedlicher Qualität erleben und vermutlich kein einheitliches Bild von der Rolle des Gerichtsdolmetschers haben. Ziel der Studie, die ich in diesem Beitrag...

  8. Päästke mööbel! / Marko Rillo

    Index Scriptorium Estoniae

    Rillo, Marko

    2006-01-01

    Näide üle-eestilise juhtimiskonkursi "Juhtimisaju 2006" ühest ülesandest ning võistkonna "Mõistuse hääl" probleemilahendus. Lisa: Ülesanne; Vt. samas: Kas tankis põlenud poiste aeg pole mitte läbi? Lisa: Teinto Furniture'i SWOT analüüs

  9. Human Resources Management in the Belgian TSO Bel V

    International Nuclear Information System (INIS)

    Roobaert, Marika; Bernard, Benoît; Mignot, Pierre

    2014-01-01

    Conclusions: → 2013: Reorganisation of HRM process to include SARCoN: → Role descriptions (+ associated tasks) X 2; → CGA using SARCoN methodology included. → PILOT application of CGA with SARCoN launched & completed: → 2 competence profiles (for 2 technical key roles) by 10 test persons; → Self-assessment validated with coach/supervisor; → Training Manager has performed CGA. → Significant differences identified in interpretation of KSA content & level; → Next steps: → Thorough evaluation of pilot application; → Define more detailed guidance!! → Future challenge: Larger scale use of SARCoN

  10. Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for iPLA2beta.

    Science.gov (United States)

    Ma, Z; Ramanadham, S; Wohltmann, M; Bohrer, A; Hsu, F F; Turk, J

    2001-04-20

    A cytosolic 84-kDa group VIA phospholipase A(2) (iPLA(2)beta) that does not require Ca(2+) for catalysis has been cloned from several sources, including rat and human pancreatic islet beta-cells and murine P388D1 cells. Many potential iPLA(2)beta functions have been proposed, including a signaling role in beta-cell insulin secretion and a role in generating lysophosphatidylcholine acceptors for arachidonic acid incorporation into P388D1 cell phosphatidylcholine (PC). Proposals for iPLA(2)beta function rest in part on effects of inhibiting iPLA(2)beta activity with a bromoenol lactone (BEL) suicide substrate, but BEL also inhibits phosphatidate phosphohydrolase-1 and a group VIB phospholipase A(2). Manipulation of iPLA(2)beta expression by molecular biologic means is an alternative approach to study iPLA(2)beta functions, and we have used a retroviral construct containing iPLA(2)beta cDNA to prepare two INS-1 insulinoma cell clonal lines that stably overexpress iPLA(2)beta. Compared with parental INS-1 cells or cells transfected with empty vector, both iPLA(2)beta-overexpressing lines exhibit amplified insulin secretory responses to glucose and cAMP-elevating agents, and BEL substantially attenuates stimulated secretion. Electrospray ionization mass spectrometric analyses of arachidonic acid incorporation into INS-1 cell PC indicate that neither overexpression nor inhibition of iPLA(2)beta affects the rate or extent of this process in INS-1 cells. Immunocytofluorescence studies with antibodies directed against iPLA(2)beta indicate that cAMP-elevating agents increase perinuclear fluorescence in INS-1 cells, suggesting that iPLA(2)beta associates with nuclei. These studies are more consistent with a signaling than with a housekeeping role for iPLA(2)beta in insulin-secreting beta-cells.

  11. MicroRNA-214-5p Inhibits the Invasion and Migration of Hepatocellular Carcinoma Cells by Targeting Wiskott-Aldrich Syndrome Like.

    Science.gov (United States)

    Li, Hongdan; Wang, Haoqi; Ren, Zhen

    2018-01-01

    This study aims to explore the effects of microRNA-214-5p (miR-214-5p) on the invasion and migration of Hepatocellular Carcinoma cells (HCC). Hepatocellular Carcinoma tissues and adjacent normal tissues from 44 hepatocellular carcinoma patients were prepared for this study. The HepG2 and BEL-7402 cells were transfected with miR-214-5p mimic and inhibitor. qRT-PCR was performed to detect the expressions of miR-214-5p. Transwell assays were used to detect the invasion and migration assays in HepG2 and BEL-7402 cells. A dual-luciferase reporter assay was conducted to examine the effect of miR-214-5p on Wiskott-Aldrich Syndrome Like (WASL/ N-WASP). Western blot and qRT-PCR were used to measure the expressions of the E-cadherin, N-cadherin and Vimentin proteins. Transwell chamber assays were performed to detect cell invasion and migration. Compared with normal tissues, HCC tissues demonstrated significantly lower expression of miR-214-5p. Overexpression of miR-214-5p significantly inhibited the migration and invasion of HCC cells and inhibition of miR-214-5p promoted the migration and invasion. Additionally, miR-214-5p suppressed the epithelial-mesenchymal transition (EMT). Further study showed WASL was a putative target gene of miR-214-5p. Up-regulating the expression of WASL could reverse the inhibition effect of miR-214-5p on invasion and migration. Our data suggested that miR-214-5p inhibited the invasion and migration of HepG2 and BEL-7402 by targeting WASL in Hepatocellular carcinoma. © 2018 The Author(s). Published by S. Karger AG, Basel.

  12. Tropospheric Ozone: a Menace for Crops and Natural Vegetation in Greece

    Directory of Open Access Journals (Sweden)

    Costas Saitanis

    Full Text Available Based on instrumental monitoring (AOT40s and phytodetection (with Bel-W3 and KK6/5 tobacco cultivars data we evaluated ambient ozone phytotoxicity in Greece. In the greater region of Mesogia-Attica, during the summer of 2000, the year before the new airport Eleftherios Venizelos (March 2001 began operating in this region, the AOT40s (ppb*h were 16,325 over 110 days at Spata; 18,646 over 113 days at Markopoulo; 8,093 over 22 days at Artemis and 16,679 over 121 days in Athens. The Bel- W3 and KK6/5 plants were extensively injured at all places with the greatest injury occurring at Artemis. During the same summer, ozone was also monitored in three rural areas of Corinth, at the Astronomical Observatory of Krionerion, Bogdani Hill and Kiato; The highest average daily AOT40 (192 ppb*h was observed in Krionerio, and it was almost equal to that occurred in Athens (193 ppb*h. Bel-W3 and KK6/5 plants placed at 11 rural areas in Corinth showed extended injury. The following year (2001, high injury was observed on other sets of bioindicator plants exposed in a network of 28 locations throughout the greater area of Volos and Pelion Mountain. Symptoms were more severe at Mortias, Xinovrisi, Tsagarada, Makrinitsa and Chania. The AOT40 (May-July was 11,391 and 10,351 ppb*hours for 2001 and 2002 respectively. Severe ozone-like symptoms have also been observed on field-cultivated grape vines, onion and watermelon plants. Synoptically, our investigations suggest that ozone occurs in the Greek mainland at levels that are potentially phytotoxic for sensitive crop species and for sensitive natural vegetation species including forest trees.

  13. [Synthesis of a supermolecular nanoparticle γ-hy-PC/Ada-Dox and its antitumor activity].

    Science.gov (United States)

    Li, Yong-bin; Wang, Kai; Hu, Tian-nan; Wang, Qi-wen; Hu, Qi-da; Zhou, Jun; Hu, Xiu-rong; Tang, Gu-ping

    2012-11-01

    To synthesize a (2-Hydroxypropyl)-γ-cyclodextrin-polyethylenimine/adamantane-conjugated doxorubicin (γ-hy-PC/Ada-Dox) based supramolecular nanoparticle with host-guest interaction and to identify its physicochemical characterizations and antitumor effect. A novel non-viral gene delivery vector γ-hy-PC/Ada-Dox was synthesized based on host-guest interaction. 1H-NMR, NOESY, UV-Vis, XRD and TGA were used to confirm the structure of the vector. The DNA condensing ability of complexes was investigated by particle size, zeta potential and gel retardation assay. Cytotoxicity of complexes was determined by MTT assay in BEL-7402 and SMMC-7721 cells. Cell wound healing assay was performed in HEK293 and BEL-7404 cells. The transfection efficiency was investigated in HEK293 cells. H/E staining and cell uptake assay was performed in BEL-7402 cells. The structure of γ-hy-PC/Ada-Dox was characterized by 1H-NMR, NOESY, UV-Vis, XRD, TGA. The drug loading was 0.5% and 5.5%. Gel retardation assay showed that γ-hy-PC was able to completely condense DNA at N/P ratio of 2; 0.5% and 5.5% γ-hy-PC/Ada-Dox was able to completely condense DNA at N/P ratio of 3 and 4,respectively. The cytotoxicity of polymers was lower than that of PEI25KDa. The transfection efficiency of γ-hy-PC was higher than that of γ-hy-PC/Ada-Dox at N/P ratio of 30 in HEK293 cells; and the transfection efficiency was decreasing when Ada-Dox loading was increasing. Cell uptake assay showed that γ-hy-PC/Ada-Dox was able to carry drug and FAM-siRNA into cells. The novel vector γ-hy-PC/Ada-Dox has been developed successfully, which has certain transfection efficiency and antitumor activity.

  14. Primer Certamen Frenopático Español (1883: estructura asistencial y aspectos administrativos

    Directory of Open Access Journals (Sweden)

    Villasante Armas, Olga

    1997-06-01

    Full Text Available In the latter part of the XIX century, an important group of physicians worked in Nueva Belén, a Mental Hospital located near Barcelona. Juan Giné y Partagás, the Director of Nueva Belén and his colleagues undertook investigation, clinical and academic work. This group organized the most important scientific meeting on Psychiatry in the last century in Spain, although Psychiatry had not yet been recognized as an independent science. The present article describes the organization and contents of the "Primer Certamen Frenopático Español" using the original records. It is mainly focused on the Congress communications which deal with administrative and asistencial aspects of that time.

    En el último tercio del siglo XIX un grupo de profesionales de la Medicina trabajaba en Nueva-Belén, hospital psiquiátrico localizado en las proximidades de Barcelona. Juan Giné y Partagás, director de este manicomio, y sus colaboradores, realizaban una labor clínica, académica y de investigación. Fue este grupo el que organizó la reunión más importante sobre Psiquiatría que tuvo lugar en el pasado siglo en España, en un momento en el que la especialidad no era, aún, reconocida como una disciplina científica independiente del resto de la Medicina. El presente artículo describe la organización y contenidos del "Primer Certamen Frenopático Español" utilizando como material las actas originales del Congreso. Se centra en el análisis de las comunicaciones presentadas, cuyos contenidos temáticos son los aspectos administrativos y asistenciales de la frenopatología de la época.

  15. Mental health trajectories from childhood to young adulthood affect the educational and employment status of young adults: results from the TRAILS study.

    Science.gov (United States)

    Veldman, Karin; Reijneveld, Sijmen A; Ortiz, Josue Almansa; Verhulst, Frank C; Bültmann, Ute

    2015-06-01

    Young adults at work without basic educational level (BEL), and young adults in Neither Employment, Education nor Training (NEET) are at high risk of adverse employment outcomes. Evidence lacks on the impact of mental health problems during childhood, adolescence and young adulthood on employment outcomes of young adults. Therefore, the aims of this study were to (1) identify trajectories of mental health problems from childhood to young adulthood and (2) investigate the relation between these trajectories and the educational or employment status of young adults. Data were used from the Tracking Adolescents' Individual Lives Survey (TRAILS), a Dutch prospective cohort study with 9-year follow-up. Trajectories of mental health problems measured at ages 11, 13.5, 16 and 19 years were identified in 1711 young adults with latent class growth models. Young adults with high-stable trajectories of total problems, from childhood to young adulthood, were more likely to work without BEL or be in NEET at age 19, than to be at school or to work with BEL (28.0% vs 16.0%, p=0.01). The same was found for externalising problems (35.3% vs 23.2%, p=0.02). For internalising and attention problems, no statistically significant differences were found. Young adults with high-stable trajectories of mental health problems from age 11 to 19, were at risk of adverse employment outcomes. Interventions reducing mental health problems in childhood may improve the educational or employment status of young adults and their chances for successfully entering the labour market. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  16. MarkIT büroo = Offices of MarkIT

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Pärnu mnt. 102C asuvas büroohoones paikneva MarkIT büroo sisekujundusest. Sisearhitektid Kard Männil (SAB Miu Miu Miu) ja Loreida Hein (Studio La), nende tähtsamate tööde loetelu. Valge büroomööbel on sisearhitektide projekteeritud. Graafika on sisearhitektid ise joonistanud

  17. Alfred Nobel og hans priser

    DEFF Research Database (Denmark)

    Nielsen, Henry

    2017-01-01

    Siden 1901er der næsten hvert år blevet uddelt nobelpriser for fysik, kemi, fysiologi eller medicin, litteratur og fredsarbejde. Men hvad var det, der fik prisernes ophavsmand til at belønne netop disse fem felter? Og hvordan finder de ansvarlige i Stockholm og Oslo frem til årets prisvindere. De...

  18. Kaubamaja "Lemon" - Arco Ärikeskus : Estonia pst. 1, Tallinn

    Index Scriptorium Estoniae

    2002-01-01

    1958. a. valminud hoone rekonstrueerimine. Projekteerija: EA Reng. Arhitekt Martin Aunin. Ehituskonstruktsioonid: Riho Märtson. Insenertehnilised osad: Karmo Pajo, Maarika Kurvits, Eha Treial. Valgusinstallatsioon: Meeli Kõiva. Kaupluste mööbel, kohtvalgustus: Priit Põldme, Ants Tolli, Ruth-Helene Kaasik, Hugo Mitt, Mart Vesker, Tarmo Piirmets. Projekt 2001, valmis 2002. I korruse põhiplaan, 4 vaadet

  19. Restoran Chedi = Chedi Restaurant

    Index Scriptorium Estoniae

    2009-01-01

    Eesti Sisearhitektide Liidu 2008. a. söögikoha preemia pälvinud Tallinnas Sulevimägi 1 asuva restorani Chedi sisekujundusest. Sisearhitekt Toomas Korb, tema tähtsamate tööde loetelu. Tammest mööbel on valminud eritellimusel. Aasiapärased stiilivõtted on keskaegse ruumi miljööga dialoogis

  20. Author Details

    African Journals Online (AJOL)

    Cui, Y. Vol 10, No 2 (2013) - Articles The anti-tumor effect and biological activities of the extract JMM6 from the stem-barks of the Chinese Juglans Mandshurica maxim on human hepatoma cell line bel-7402. Abstract PDF. ISSN: 0189-6016. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for ...

  1. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    BARC has developed large-area silicon detectors in collaboration with BEL to be used in the pre-shower detector of the CMS experiment at CERN. The use of floating guard rings (FGR) in improving breakdown voltage and reducing leakage current of silicon detectors is well-known. In the present work, it has been ...

  2. Role of c-Src inhibitor in the regulation of hepatocarcinoma cell ...

    African Journals Online (AJOL)

    SAM

    2014-03-19

    Mar 19, 2014 ... BEL-7402 cell line was used as HCC cell model for investigating the regulation of cell migration upon c-. Src inhibitors (PP2 and .... PDGF-BB were purchased from Enzo Life Sciences International,. USA; SU6656 Sigma (USA). .... Statistical analysis was done with Student's t-test for comparison of two ...

  3. Raamat / Matis Rodin

    Index Scriptorium Estoniae

    Rodin, Matis

    2012-01-01

    Raamatututvustus: Paulus, Karin. Tootedisain : asjad minu elus. Tallinn : Eesti Kunstiakadeemia, 2011; Vainküla, Tõnu, Pere, René. Vana mööbel korda oma kätega. [Tallinn] : Ajakirjade Kirjastus, 2012; Ruumipilt 2011 : Eesti parimad interjöörid ja disain / Eesti Sisearhitektide Liit ; toimetaja ja vastutav väljaandja Priit Põldme. Tallinn, 2012

  4. Fulltext PDF

    Indian Academy of Sciences (India)

    Feronia limonia (L.) S~villg/e (B. Koet Bel) (English: Elephant- or Wood-apple; Hindi: Kaithbel, Kaitha,. Kavitha) of Rutaceae is a medium-sized deciduous tree with thorny branches and compound leaves. Flowers are small and white. Fruits are large, globose, of the size of tennis balls with a hard and woody shell enclosing ...

  5. DISEÑO DE UNA PROPUESTA DE MARKETING ECOTURÍSTICO PARA EL MUNICIPIO DE LA PLAYA DE BELÉN COMO DESTINO TURÍSTICO

    Directory of Open Access Journals (Sweden)

    Luis Alfonso Sánchez Borja

    2014-06-01

    Full Text Available El proyecto tiene como objetivo diseñar una propuesta de Marketing Ecoturístico para el Municipio de la Playa de Belén en el departamento de Norte de Santander, Colombia; se presentan los aspectos generales del Municipio, tales como; ubicación geográfica, topografía, aspectos étnicos y culturales. Seguidamente describe el análisis DOFA, la metodología y conceptos utilizados de mayor interés que aportan al desarrollo de la investigación con el fin de realizar un diagnóstico turístico sobre los componentes de intangibilidad turística, superestructura, infraestructura, planta turística, atractivos y descripción cultural de la comunidad de la Playa de Belén. Los resultados obtenidos se reflejan a través del análisis de mercado mediante encuesta aplicada a la comunidad, operadores y turistas, se analiza la situación actual, se diseña el plan de marketing creando unos objetivos, estrategias y recomendaciones de proyección para el municipio.

  6. Cartas de imigrantes como fonte para o historiador: Rio de Janeiro ­ Turíngia (1852-1853

    Directory of Open Access Journals (Sweden)

    Débora Bendocchi Alves

    2003-07-01

    Full Text Available O artigo apresenta nove cartas de imigrantes alemães residentes nas fazendas de café do Rio de Janeiro. Foram publicadas em 1852/53 nos jornais de Günther Fröbel, em Rudolstadt, com o intuito de incentivar a emigração para as fazendas de café fluminenses que haviam adotado o sistema de parceria em substituição ao sistema de trabalho escravo. Além de desempenharem a função de incentivo à emigração, construíram uma imagem do Brasil especificamente para imigrantes.This article presents nine letters of German immigrants living in coffee-plantations in the state of Rio de Janeiro. They were published in 1852/53 in Günther Fröbel's newspapers in Rudolstadt. The intention was to encourage an emigration to the fluminense coffee-plantation, which had adopted a "parceria system" instead of slavery. Besides playing a part in the promotion of the emigration they built specific images of Brazil for immigrants.

  7. New Pathways between Group Theory and Model Theory

    CERN Document Server

    Fuchs, László; Goldsmith, Brendan; Strüngmann, Lutz

    2017-01-01

    This volume focuses on group theory and model theory with a particular emphasis on the interplay of the two areas. The survey papers provide an overview of the developments across group, module, and model theory while the research papers present the most recent study in those same areas. With introductory sections that make the topics easily accessible to students, the papers in this volume will appeal to beginning graduate students and experienced researchers alike. As a whole, this book offers a cross-section view of the areas in group, module, and model theory, covering topics such as DP-minimal groups, Abelian groups, countable 1-transitive trees, and module approximations. The papers in this book are the proceedings of the conference “New Pathways between Group Theory and Model Theory,” which took place February 1-4, 2016, in Mülheim an der Ruhr, Germany, in honor of the editors’ colleague Rüdiger Göbel. This publication is dedicated to Professor Göbel, who passed away in 2014. He was one of th...

  8. Diverse regulation of retinal pigment epithelium phagocytosis of photoreceptor outer segments by calcium-independent phospholipase A₂, group VIA and secretory phospholipase A₂, group IB

    DEFF Research Database (Denmark)

    Zhan, Chen; Wang, Jinmei; Kolko, Miriam

    2012-01-01

    PURPOSE: To investigate the roles of the phospholipases A(2) (PLA(2)) subtypes, iPLA(2)-VIA and sPLA(2)-IB in retinal pigment epithelium (RPE) phagocytosis of photoreceptor outer segments (POS) and to explore a possible interaction between sPLA(2)-IB and iPLA(2)-VIA in the RPE. METHODS: To explore...... the role of iPLA(2)-VIA in RPE phagocytosis of POS, experiments with iPLA(2)-VIA vector transfection, iPLA(2)-VIA(-/-) knockout (KO) mice, and iPLA(2)-VIA inhibition by bromoenol lactone (BEL) were done. Exogenous addition of sPLA(2)-IB was used to investigate the role of sPLA(2)-IB in RPE phagocytosis....... A Luciferase Reporter Vector containing the iPLA(2)-VIA promoter was used to study the effects of sPLA(2)-IB on the iPLA(2)-VIA promoter. RESULTS: ARPE-19 and primary mouse RPE cells transfected with iPLA(2)-VIA showed increased phagocytosis. Phagocytosis was reduced in primary mouse RPE inhibited with BEL...

  9. Manufacturing ceramic bricks with polyaluminum chloride (PAC) sludge from a water treatment plant.

    Science.gov (United States)

    da Silva, E M; Morita, D M; Lima, A C M; Teixeira, L Girard

    2015-01-01

    The objective of this research work is to assess the viability of manufacturing ceramic bricks with sludge from a water treatment plant (WTP) for use in real-world applications. Sludge was collected from settling tanks at the Bolonha WTP, which is located in Belém, capital of the state of Pará, Brazil. After dewatering in drainage beds, sludge was added to the clay at a local brickworks at different mass percentages (7.6, 9.0, 11.7, 13.9 and 23.5%). Laboratory tests were performed on the bricks to assess their resistance to compression, water absorption, dimensions and visual aspects. Percentages of 7.6, 9.0, 11.7 and 13.9% (w/w) of WTP sludge presented good results in terms of resistance, which indicates that technically, ceramic bricks can be produced by incorporating up to 13.9% of WTP sludge.

  10. Uus eesti disain / Ene Läkk

    Index Scriptorium Estoniae

    Läkk, Ene, 1957-

    2009-01-01

    2009. a. disainiöö raames toimunud Eesti Disainerite Liidu algatatud konkursi "Eesti disain ja elukeskond 2009" disainikategooria kümne finalisti tööde tutvustus. 1. koha sai moodulrattahoidja "Rohi" (disain: Keha3), 2. koha vurr-tool "Kiirendi" (disain: Jaanus Orgusaar), 3. koha lastemööbel "Smart kid" (disain: Pavel Sidorenko, Heiki Must)

  11. An integrative taxonomy approach unveils unknown and threatened moth species in Amazonian rainforest fragments

    Czech Academy of Sciences Publication Activity Database

    Lamarre, Greg P. A.; Decaëns, T.; Rougerie, R.; Barbut, J.; Dewaard, J. R.; Hebert, P. D. N.; Herbin, D.; Laguerre, M.; Thiaucourt, P.; Martins, M. B.

    2016-01-01

    Roč. 9, č. 5 (2016), s. 475-479 ISSN 1752-458X EU Projects: European Commission(XE) 669609 - Diversity6continents Institutional support: RVO:60077344 Keywords : Amazonian forest * Belém center of endemism * centinelan extinction Subject RIV: EG - Zoology Impact factor: 1.840, year: 2016 http://onlinelibrary.wiley.com/doi/10.1111/icad.12187/full

  12. 1172-IJBCS-Article-Kadidia Sanon

    African Journals Online (AJOL)

    DR GATSING

    2 Laboratoire de Biologie et Physiologie Végétales, Université Antilles-Guyane, BP. 592, 97159 Pointe-à-. Pitre, Guadeloupe, France. E-mail : Amadou.Ba@ird.fr . 3 Laboratoire Commun de Microbiologie (UCAD-IRD-ISRA), BP 1386 Bel Air, Dakar, Sénégal. *Auteur correspondant, E-mail : sbkady@gmail.com; Tél : 226 50 ...

  13. Disainikaart : Šveits

    Index Scriptorium Estoniae

    2008-01-01

    Šveitsi praktilist, atraktiivset ja nutikat disaini esindavad Le Corbusier ja Mario Botta arhitektuur, Adrien Rovero installatsioon, Bernard Tschumi uued vormid arhitektuuris, Herzog & de Meuroni Pekingi olümpiastaadion, disainibüroode Big Game, Fulguro, It Desing mööbel ja valgustid, D'Esposito ja Gaillardi tootedisain kandiku näol ja Nicolas Le Moigne nutikas kastekann

  14. Il significato della relatività

    CERN Document Server

    Einstein, Albert

    1955-01-01

    La prima edizione di questo libro, pubblicata bel 1922, comprendeva il testo delle Stafford Little Lectures tenute da Einstein nel maggio 1921 alla Università di Princeton. Nel 1945 Einstein aggiunse un'appendice sulla sua teoria generalizzata della gravitazione. Nel 1953 Einstein rifece del tutto, ampliandola, la seconda appendice, a cui aggiunse un Supplemento nel 1954.

  15. Phase II activity of belinostat (PXD-101), carboplatin, and paclitaxel in women with previously treated ovarian cancer

    DEFF Research Database (Denmark)

    Dizon, Don S; Damstrup, Lars; Finkler, Neil J

    2012-01-01

    specifically for women with recurrent epithelial ovarian cancer (EOC). METHODS: Thirty-five women were treated on the phase 2 expansion cohort. BelCap was given as follows: belinostat, 1000 mg/m² daily for 5 days with carboplatin, AUC 5; and paclitaxel, 175 mg/m² given on day 3 of a 21-day cycle. The primary...

  16. Author Details

    African Journals Online (AJOL)

    Wang, X. Vol 10, No 2 (2013) - Articles The anti-tumor effect and biological activities of the extract JMM6 from the stem-barks of the Chinese Juglans Mandshurica maxim on human hepatoma cell line bel-7402. Abstract PDF · Vol 10, No 3 (2013) - Articles Experimental study on inhibition of s180 tumor cells by Agrimonia ...

  17. Tallinna Ülikooli Balti Filmi- ja Meediakooli õppehoone Nova = Tallinn University Baltic Film and Media School "Nova"

    Index Scriptorium Estoniae

    2015-01-01

    Tallinna Ülikooli Balti Filmi- ja Meediakooli õppehoone "Nova" Narva maantee 27, valminud 2012. Arhitektuuri sihtkapitali arhitektuuripreemia 2012 ja Arhitektuuri sihtkapitali sisearhitektuuripreemia 2013. Arhitektid Maarja Kask, Karli Luik, Ralf Lõoke, Pelle-Sten Viiburg (Salto Arhitektid). Sisearhitektid Ville Lausmäe, Kadi Karmann (VLS). Mööbel Ville Lausmäe, Tõnis Kalve. Konstruktor Jaanus Natka (EA Reng)

  18. SUPPLEMENTARY COMPARISON: COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

    Science.gov (United States)

    Skliarov, V.; Röttger, A.; Honig, A.; Korostin, S.; Kuznetsov, S.; Lapenas, A.; Milevsky, V.; Ivaniukovich, A.; Kharitonov, I.; Sepman, S.

    2009-01-01

    According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5th meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by COOMET, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  19. LA ALFARERÍA DEL TARDÍO PREHISPÁNICO DEL VALLE DEL BOLSÓN (CATAMARCA, ARGENTINA: ¿PRODUCCIÓN LOCAL O ALÓCTONA? / The Late Prehispanic pottery of the Bolsón Valley (Catamarca, Argentine: local or allochthonous production?

    Directory of Open Access Journals (Sweden)

    Verónica Puente

    2014-11-01

    Full Text Available En este trabajo se presentan los resultados obtenidos en los estudios de procedencia de conjuntos cerámicos recuperados en dos asentamientos conglomerados del valle del Bolsón (Belén, Catamarca, Argentina vinculados a ocupaciones del tardío prehispánico (ca. 900-1600 DC. Las muestras estudiadas corresponden principalmente a cerámica pintada en negro sobre rojo reconocida como de estilo Belén, en menor medida ordinaria y excepcionalmente negro sobre crema y ante. Se complementaron análisis petrológicos y análisis por activación neutrónica instrumental realizados a la alfarería y a materias primas adecuadas para la producción alfarera muestreadas en la región. Se concluye que un grupo mayoritario de piezas fueron elaboradas con arcillas y arenas procedentes de la región bajo estudio. Asimismo, se destacan similitudes composicionales entre la vajilla recuperada en ambos asentamientos a pesar de las diferencias logísticas y estratégicas de emplazamiento. Los resultados generados son un importante aporte al tema de la producción alfarera a escala suprarregional dado que evidencian la coexistencia de distintos locus de producción cerámica en el oeste catamarqueño durante el lapso temporal estudiado.   Palabras clave: cerámica, tardío prehispánico, procedencia, análisis de activación neutrónica, petrografía.   Abstract The results obtained in the study of the provenance of ceramic recovered in two conglomerates settlements of the valley of El Bolsón (Belén, Catamarca, Argentina linked to prehispanic late occupations (ca. 900-1600 AD are given. The samples analyzed correspond mainly to Belén style ceramic, in lesser frequency to ordinary, and exceptionally to black over cream and beige. This study combined petrological and neutron instrumental activation analysis made in both kind of samples, archaeological pottery and local raw materials. It is concluded that a majority of archaeological pottery were made with clay and

  20. Características qualitativas de genótipos de cebola Qualitative characteristics of onion genotypes

    Directory of Open Access Journals (Sweden)

    Leilson Costa Grangeiro

    2008-08-01

    Full Text Available Objetivou-se, com o trabalho, avaliar alguns atributos de qualidade de diferentes genótipos de cebola (Allium cepa L., cultivados em Mossoró-RN. O experimento foi realizado na horta experimental no Departamento de Ciências Vegetais da Universidade Federal Rural do Semi-Árido, em delineamento de blocos casualizados completos e quatro repetições. Os tratamentos foram constituídos pelos genótipos de cebola CNPH 6415, CNPH 6047, CNPH 6244, CNPH 6400 Chata, CNPH 6400 Redonda, CPACT 1, CPACT 2, CPACT 3, Granex 429, Belém IPA 9, BRS Cascata, Crioula Alto Vale, Bola Precoce, Primavera, Régia, Valeouro IPA-11, Brisa e Alfa São Francisco. As características avaliadas foram teor de sólidos solúveis totais, acidez total titulável, teor de vitamina C e teor de ácido pirúvico (pungência. Foram observadas diferenças significativas entre os genótipos para todas as características avaliadas. Os genótipos apresentaram uma variação significativa para todas as características avaliadas, confirmando dessa forma que o fator genético é determinante na caracterização de cada material. O teor de sólidos solúveis totais variou de 6,67 a 11,63 (º Brix, vitamina C de 22,7 a 46,81 (mg ácido ascórbico/100 ml de suco e a acidez total titulável de 0,19 a 0,45 (% de ácido pirúvico. Os genótipos apresentaram pungência intermediária com variação de 5,0 a 12,73 (µmol/g, sendo os menos pungentes Granex 429, CNPH 6047, Régia, Primavera e Belém IPA 9.The aim of this work was to evaluate some attributes of quality of different genotypes of onion (Allium cepa L., cultivated in Mossoró-RN. The experiment was carried out in the vegetable garden of Plant Science Department at Universidade Federal Rural do Semi-Árido. The experimental outline was of randomized complete blocks with four replications. The treatments were constituted by the genotypes of onion CNPH 6415, CNPH 6047, CNPH 6244, CNPH 6400 Chata, CNPH 6400 Redonda, CPACT 1, CPACT 2

  1. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... José Manuel Cozar José Francisco Suárez-Novo Manel Castells-Esteve Pablo Fernández-Gonzalo Belén De-Paula-Carranza Montse Ferrer Ferrán Guedea Gemma Sancho-Pardo Jordi Craven-Bartle María José Ortiz-Gordillo Patricia Cabrera-Roldán Estefanía Herrera-Ramos Carlos Rodríguez-Gallego Pedro C. Lara.

  2. Betaler det sig? Fleksibilitet og løn i den danske flexicurity-model

    DEFF Research Database (Denmark)

    Ibsen, Flemming

    2007-01-01

    Indkomstsikkerhed er at bevæge sig fra et job til at andet og få en højere løn, men er det tilfældet i dan danske flexicurity-model, betaler det sig at være fleksibel? Belønnes numerisk ekstern fleksibiblitet højrere end intern funktionel fleksibilbitet? Artiklen viser, at det bedst kan betale si...

  3. Eesti Disaini muna BRUNO said Martin Pärn ja Annike Laigo / Urve Eslas

    Index Scriptorium Estoniae

    Eslas, Urve

    2006-01-01

    Eesti Disainerite Liidu auhinnad parima tootedisaini ja parima disainiprojekti eest pälvisid Martin Pärn büroomööbli seeria "Krog" eest ning Annike Laigo isehelenduva vaiba "Jaaniuss" eest. Samal teemal ka lk. 1 "Büroomööbel ja helendav vaip võitsid disaini-BRUNO". Eesti Disaini auhinna nominentide näitus on avatud Disaini- ja Arhitektuurigaleriis

  4. Copépodes, Cladocères et Rotifères du lac Sidi M'hamed Benali (Algérie Nord-Occidentale

    Directory of Open Access Journals (Sweden)

    Mohamed Ali Bouzidi

    2010-03-01

    Full Text Available En 2008, 33 espèces de Cladocères, Copépodes et Rotifères ont été observées dans le lac Sidi M'hamed Benali (contre 12 seulement en 1992.Les Copépodes dominent en mars, avril, juillet, août et septembre, avec respectivement des dominances (Do égales à : 56,6 %, 55,0 %, 55,0 %, 46,4 % et 90,0 %. Les Cladocères dominent en février (Do = 37,2 %, mai (Do = 47,4 % et décembre (Do = 48,6 %. Les Rotifères sont extrêmement abondants et présentent une large dominance en janvier (Do = 95,3 %. La population zooplanctonique est très faible en juillet et en août. Au cours de l'année le peuplement varie en fonction de la température, des conditions hydrologiques, de l'abondance de la nourriture et de la prédation par les poissons.In 2008, 33 species of Cladocers, Copepods and Rotifers have been observed in Sidi M’hamed Benali Lake (against only 12 species in 1992. The Copepods dominate in March, April, July, August and September, respectively with dominance (Do equal to 56.6 %, 55.0 %, 55.0 %, 46.4 % and 90.0 %. Cladocers dominated in February (Do = 37.2 %, May (Do = 47.4 % and December (Do = 48.6 %. The rotifers are extremely abundant and have a wide dominance in January (Do = 95.3%. The zooplankton population is very low in July and August. During the year, the population varies with temperature, water conditions, abundance of food and predation by fishes.

  5. In situ monitoring of mutagenicity of air pollutants in São Paulo City using Tradescantia-SHM bioassay

    Directory of Open Access Journals (Sweden)

    Ferreira Maria Izildinha

    2003-01-01

    Full Text Available The Tradescantia stamen hair mutation assay (Trad-SHM was employed for assessing the environmental mutagenesis in two areas of São Paulo City. The study sites were defined as follows: 1 Celso Garcia Avenue, an industrial area on the outskirts of the urban center (Belém neighborhood, with an average daily traffic volume of 8,750 vehicles; 2 Doutor Arnaldo Avenue, in downtown area (Pinheiros neighborhood, with a mostly residential and business offices occupation, with an average daily traffic volume of 46,125 vehicles. The negative control (background site is located in the city of Jaguariúna, 138 km from São Paulo, in an area of low atmospheric pollution. The mutation frequency observed for Belém was similar to the background for clone 4430, whereas plants exposed in Pinheiros showed significant increases in mutation rate. Positive correlation was observed between mutation frequency and the levels of particulate matter in the atmosphere. This indicated a relationship between mutation frequency and the amount of atmospheric pollution present at the exposure sites in São Paulo City, with special reference to vehicular emissions.

  6. MAPEAMENTO GEOLITERÁRIO: UMA PROPOSTA METODOLÓGICA PARA OS ESTUDOS GEOGRÁFICOS

    Directory of Open Access Journals (Sweden)

    Walter Luiz Jardim Rodrigues

    2016-06-01

    Full Text Available Os romances são produções literárias que abrigam em suas páginas, variadas possibilidades de estudos. Embora pouco explorados neste sentido, seus estudos podem ser muito úteis não somente para linha de pesquisa da Geografia e Literatura, mas para diversos ramos do conhecimento como a percepção ambiental, urbanismo, história, economia e entre outros. Neste sentido, procura-se contribuir com uma abordagem metodológica para apreensão do espaço geográfico através de obras literárias, e nesse estudo, a análise do espaço geográfico da cidade de Belém do Pará da década de 1920, descrita no romance “Belém do Grão-Pará” de Dalcídio Jurandir. E assim comparar com a atual organização espacial da cidade a partir do uso das geotecnologias para espacializar, identificar, analisar e representar o espaço através de mapas temáticos gerados a partir do mapeamento geoliterário.

  7. Caso incomum de filariose linfática mediastinal com estenose da artéria pulmonar

    Directory of Open Access Journals (Sweden)

    Moacir Boreli Tormes

    1988-03-01

    Full Text Available E descrito um caso incomum de filariose linfática, devido a Wuchereria Bancrofti, com localização dos vermes nos linfonodos e linfáticos do mediastino. A intensa reação do conjuntivo mediastinal, provavelmente desencadeada por macrofilárias mortas, determinou no paciente - de 9 anos, residente em Belém, Estado do Pará - estreitamento do tronco e dos ramos principais da artéria pulmonar, defeito tido, inicialmente, como de natureza congênita. O exame histopatológico de duas dentre várias formações nodulares encontradas no mediastino, durante o ato operatório,permitiu, no entanto, estabelecer-se a verdadeira causa da alteração exibida pelo paciente. O achado representa uma formà curiosa de infecção por W. bancrofti, completamente inesperada, quando se considera que a prevalência da bancroftose é, hoje, muito baixa na cidade de Belém. Segundo dados oficiais, o índice de microfilaremia atingiu, em 1985, nessa cidade, cerca de 0,1% apenas, enquanto que, há algumas décadas, era ele estimado em mais de 10%.

  8. Hidden Broad-line Regions in Seyfert 2 Galaxies: From the Spectropolarimetric Perspective

    International Nuclear Information System (INIS)

    Du, Pu; Wang, Jian-Min; Zhang, Zhi-Xiang

    2017-01-01

    The hidden broad-line regions (BLRs) in Seyfert 2 galaxies, which display broad emission lines (BELs) in their polarized spectra, are a key piece of evidence in support of the unified model for active galactic nuclei (AGNs). However, the detailed kinematics and geometry of hidden BLRs are still not fully understood. The virial factor obtained from reverberation mapping of type 1 AGNs may be a useful diagnostic of the nature of hidden BLRs in type 2 objects. In order to understand the hidden BLRs, we compile six type 2 objects from the literature with polarized BELs and dynamical measurements of black hole masses. All of them contain pseudobulges. We estimate their virial factors, and find the average value is 0.60 and the standard deviation is 0.69, which agree well with the value of type 1 AGNs with pseudobulges. This study demonstrates that (1) the geometry and kinematics of BLR are similar in type 1 and type 2 AGNs of the same bulge type (pseudobulges), and (2) the small values of virial factors in Seyfert 2 galaxies suggest that, similar to type 1 AGNs, BLRs tend to be very thick disks in type 2 objects.

  9. Combination of U.V.-B and ozone reduces pollen tube growth more than either stress alone

    International Nuclear Information System (INIS)

    Feder, W.A.; Shrier, R.

    1990-01-01

    The rate of in vitro Nicotiana tabacum L. “Bel-W3” pollen tube growth was reduced 62 and 44%, respectively, when pollen tubes were exposed to 120 ppb ozone (O 3 ) for 3 hr or 300 μW/cm 2 ultraviolet-B (u.v.-B) radiation for 30 min. Petunia hybrida Vilm. “White Cascade” pollen tube growth was reduced 34 and 59%, respectively, upon exposure to O 3 or u.v.-B at the above doses. The combination of u.v.-B at 300 μW/cm 2 for 30 min, followed by O 3 at 120 ppb for 3 hr, reduced pollen tube growth by 79% for “Bel-W3” and 75% for “White Cascade”. The effect appeared to be additive, implying that different target areas may be affected by the two stressors. In the Northeast, plants are exposed to both u.v.-B and O 3 during the normal growing season. This may result in an unexpectedly higher stress on the reproductive system than had been previously suspected based on these two stressors acting individually. (author)

  10. Vorinostat enhances the anticancer effect of oxaliplatin on hepatocellular carcinoma cells.

    Science.gov (United States)

    Liao, Bo; Zhang, Yingying; Sun, Quan; Jiang, Ping

    2018-01-01

    Oxaliplatin-based systemic chemotherapy has been proposed to have efficacy in hepatocellular carcinoma (HCC). We investigated the combination of vorinostat and oxaliplatin for possible synergism in HCC cells. SMMC7721, BEL7402, and HepG2 cells were treated with vorinostat and oxaliplatin. Cytotoxicity assay, tumorigenicity assay in vitro, cell cycle analysis, apoptosis analysis, western blot analysis, animal model study, immunohistochemistry, and quantitative PCR were performed. We found that vorinostat and oxaliplatin inhibited the proliferation of SMMC7721, BEL7402, and HepG2 cells. The combination index (CI) values were all vorinostat and oxaliplatin induced G2/M phase arrest, triggered caspase-dependent apoptosis, and decreased tumorigenicity both in vitro and in vivo. Vorinostat suppressed the expression of BRCA1 induced by oxaliplatin. In conclusion, cotreatment with vorinostat and oxaliplatin exhibited synergism in HCC cells. The combination inhibited cell proliferation and tumorigenicity both in vitro and in vivo through induction of cell cycle arrest and apoptosis. Our results predict that a combination of vorinostat and oxaliplatin may be useful in the treatment of advanced HCC. © 2017 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  11. Pärnu hotell-veekeskus Tervise Paradiis / Tüüne-Kristin Vaikla

    Index Scriptorium Estoniae

    Vaikla, Tüüne-Kristin, 1961-

    2005-01-01

    Pärnus Side t. 14 asuva hotelli-veekeskuse arhitekt on Raivo Puusepp. Sisekujundus, logo, infograafika: Tüüne-Kristin ja Urmo Vaikla, OÜ Vaikla Stuudio. Ehitaja: AS Merko Ehitus. Hotellitubade mööbel ja valamud, retseptsioonide letid, restorani-baaride lauad, sohvad, lobby vaibad on kavandatud spetsiaalselt sellele objektile. T.-K. ja U. Vaiklast, Vaikla Stuudio sisearhitektuurseid töid. Ill.: plaan, 28 värv. vaadet

  12. Sakubü bürooruumid = Sakubü bureau

    Index Scriptorium Estoniae

    2008-01-01

    Sakubü bürooruumide sisekujundus, mis pälvis Eesti Sisearhitektide Liidu 2007. a. büroointerjööri preemia. Sisearhitektid Tüüne-Kristin Vaikla ja Urmo Vaikla (Vaikla Stuudio). Kogu mööbel on projekteeritud selle ruumi eripärasid ja töötajate vajadusi arvestades. Sisearhitektidest, valik nende töid. Plaan, 5 värv. vaadet, foto sisearhitektidest

  13. Eesti disain / Silvia Pärmann

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2014-01-01

    Ahti Grünbergi ja Tõnis Kalve mööbliseeria Derelict. Maile Grünbergi disainitud toolid ja laud Madis. Taniel Kolpakovi kaubamärgile Rough Bloom disainitud köögimööbel. Kaubamärgi Varm Country uus kollektsioon Basic no 2. Kersti Laanmaa keraamilised teekannud Kiviaeg ja Jänes kapsas. Tiina Mangi kavandatud diivan Sik-Sak. Tõnis Vellama valgustimudel AET27

  14. Puit linnas - väikevormid / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2005-01-01

    Tartu Rüütli t. uus kujundus (Rene Valner, Margus Maiste, Ott Kadarik), Vallimäe trepp Rakveres (Siiri Vallner, Heidi Urb, AB Kavakava), Helsingi Tehnikakõrgkooli üliõpilaste Antti Lehto ja Teemu Seppäneni töö Helsindi disaininädala infopaviljoni konkursil, park ja aiamööbel (Nathalie Dubois, Mustapha Sanaoui) kortermajade hoovis Prantsusmaal. 8 värv. ill

  15. Effects of Uptake of Hydroxyapatite Nanoparticles into Hepatoma Cells on Cell Adhesion and Proliferation

    OpenAIRE

    Meizhen Yin; Yixia Yin; Yingchao Han; Honglian Dai; Shipu Li

    2014-01-01

    Hydroxyapatite nanoparticles (nano-HAPs) were prepared by homogeneous precipitation, and size distribution and morphology of these nanoparticles were determined by laser particle analysis and transmission electron microscopy, respectively. Nano-HAPs were uniformly distributed, with rod-like shapes sizes ranging from 44.6 to 86.8 nm. Attached overnight, suspended, and proliferating Bel-7402 cells were repeatedly incubated with nano-HAPs. Inverted microscopy, transmission electron microscopy, a...

  16. Aasta parimad interjöörid muutsid vana trendikaks / Piret Tali

    Index Scriptorium Estoniae

    Tali, Piret, 1972-

    2001-01-01

    Eesti Sisearhitektide Liidu aastapreemiad: eramu sisekujunduse preemia - Tüüne-Kristin Vaikla ja Urmas Vaikla, meelelahutusliku interjööri preemia - kohvik "Pegasus" (Gert Sarv, Margus Tammik, Tarvo H. Varres osaühisusest Front Arhitektid), ajaloolise interjööri preemia - Tallinna Reaalkooli renoveerimisprojekt Tiina Lõhmuse juhtimisel, unikaaleseme preemia - Leila Pärtelpoja kujundatud riigikogu esimehe puhkeruumi mööbel Toompeal. Nimetatud žürii koosseis

  17. Genetic and morphological variability in South American rodent ...

    Indian Academy of Sciences (India)

    Laboratório de Citogenética, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66.075-900, Brazil; Laboratório de Genética e Biologia Molecular, Universidade Federal do Pará, Campus Universitário de Bragança, Pará 68.370-000, Brazil; Departamento de Biologia e Zoologia, Instituto de Biociências, ...

  18. strong>Hvad skal vi med en hjerne?strong>

    DEFF Research Database (Denmark)

    Hermansen, Judy

    2009-01-01

    neurologen Antonio Damasio, at sikre vores overlevelse og velbefindende (i nævnte rækkefølge). Vi ved, at der findes såkaldte belønningsstrukturer i hjernen på både dyr og mennesker, som aktiverer følelser af velbehag, når vi gør "det rigtige", dvs. noget der er godt for os. Men hvordan de mere konkret...

  19. Ray & Charles Eames : aatomid, toolid ja universumi äär / Tõnu Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tõnu, 1966-2018

    1998-01-01

    Californias elanud disainiklassikutest Ray (1912-1988) ja Charles (1907-1978) Eamesist. Kasutasid oma mööbliloomingus lisaks painutatud vineerile alumiiniumi, fiiberklaasi, plastmassi, terastraati. Uuendasid vormikäsitlust, tehnoloogiat. Nende mööbel oli moodsa ja seninägematu väljanägemisega, kerge, lihtsalt töödeldav. Tegelesid ka fotograafia ja filmiga. Näitus Eamesite loomingust on avatud Londoni Disainimuuseumis. Artikli juures illustratsioonid.

  20. CRDI foire aux questions | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1. Quels sont les éléments importants à mentionner dans ma demande d'emploi ? Il importe de démontrer, au moyen d'exemples concrets, de quelle façon vos qualifications correspondent aux exigences du poste en ce qui concerne les études, l'expérience et la langue. 2. Comment saurai-je si ma demande d'emploi a bel ...

  1. Laser System Usage in the Marine Environment: Applications and Environmental Considerations

    Science.gov (United States)

    2010-12-01

    publications/pubs/index.html. Released by Bart Chadwick, Head Environmental Sciences Branch Under authority of Martin Machniak, Head Research...Nilsson and Lindstrom , 1983; Shelton, Gaten, and Chapman, 1985). Data on the effects of laser energy to corals also are lacking, although it can be...L. and M. Lindstrom . 1983. “Retinal Damage and Sensitivity Loss of a Light- Sensitive Crustacean Compound Eye (Cirolana borealis): Electron

  2. The Effects of Two Study Methods on Memory

    Science.gov (United States)

    1987-07-01

    hypothesis that optimal processing of individual words, qua individual words is sufficient to support good recall" (Craik & Tulving , 1975, p. 27...Likewise, mnemonic strategies, such as creating a story (Bel- lezza, Cheesman, & Reddy, 19/7) or categories (Mandler, Pearlstone , & Koopmans, 1969) for...that optimal retrieval per- formance is produced by extensive semantic processing for the individual item (Craik & Tulving , 1975; Hyde & Jenkins, 1973

  3. Helsingi saab eestlaste disainitud pingid / Raivo Murde

    Index Scriptorium Estoniae

    Murde, Raivo

    2010-01-01

    Eesti ettevõtte Frog Industrial Designi kaubamärgi Extery pingid "Klaar" võitsid Helsingi avaliku ruumi mööblikonkursi. Tooteseeria autoriteks on Martin Pärn, Edina Dufala-Pärn, Sven Sõrmus ja Pent Talvet disainibüroost Iseasi. Žürii valis Exteri toodangust välja ka teisi linnaruumis kasutatavaid elemente. Eestlaste disainitud linnamööbel on eksponeeritud Helsingi sisustusmessil Habitare

  4. Eurosafe-2008 - Papers and slides

    International Nuclear Information System (INIS)

    2013-01-01

    The EUROSAFE Forum 2008 focuses on 'The role of TSOs (Technical Safety Organizations) in the context of increasing demand for safety expertise' from the point of view of the authorities, TSOs and industry and presents the latest work in nuclear installation safety and research, radiation safety carried out by the founding members of ETSON - European Technical Safety Organizations Network - (GRS, IRSN, Bel V) and their partners worldwide

  5. A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas

    DEFF Research Database (Denmark)

    Vitfell-Rasmussen, Joanna; Judson, Ian; Safwat, Akmal Ahmed

    2016-01-01

    ) and 75 mg/m(2) Dox. Results. 41 patients were included (25 in phase I, 16 in phase II). Adverse events were fatigue (95%), nausea (76%), and alopecia (63%). There was one DLT, grade 3 rash/hand and foot syndrome. MTD was Bel 1000 mg/m(2)/d and Dox 75 mg/m(2). Four responses were seen: 2 PR in phase I, RR...

  6. Askeetlik ja põhjamaine mööbel / Aivo Vahemets

    Index Scriptorium Estoniae

    Vahemets, Aivo

    2005-01-01

    Eesti täispuidust disainmööbli sarjast Incognito. Toodab Pear Välile ja vendadele Jan J. Grapsile ning Ken K. Ruudule kuuluv Hea Ruum OÜ. Disainerid on Jan J. Graps ja Pear Väli, aksessuaaride disainiga töötab Kristi Jalakas

  7. Mööbel, mis äratab meis lapse / Ele Praks

    Index Scriptorium Estoniae

    Praks, Ele

    2004-01-01

    Leidlikke mööbliesemeid maailmast lastetuppa, mille autoriteks Ieva Araja ja Rihards Funts Lätist, Samantha Parsons Austraaliast, Peter Murdoch jt. Artiklis ka kodulehekülgede aadresse, kust leida toredaid istmeid ja laudu

  8. Multiple (Two) Met Bel 601 In Series Ultimate Vacuum Testing

    Energy Technology Data Exchange (ETDEWEB)

    Restivo, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-30

    SRNL Environmental and Chemical Process Technology (E&CPT) was requested to perform testing of vacuum pumps per a verbal request from the Customer, SRNL Hydrogen Processing Technology. Tritium Operations is currently having difficulties procuring the Normetex™® Model 15 m3/hr (9 CFM) vacuum pump (formerly Normetex Pompes, now EumecaSARL). One possible solution proposed by Hydrogen Processing Technology personnel is to use two Senior Aerospace Metal Bellows MB-601 vacuum pumps piped with the heads in series, and the pumps in series (Figure 1 below). This memorandum documents the ultimate vacuum testing that was performed to determine if this concept was a viable alternate vacuum pump strategy. This testing dovetails with previous pump evaluations documented in references 1 and 2.

  9. Distantiae transmission of Trypanosoma cruzi: a new epidemiological feature of acute Chagas disease in Brazil.

    Directory of Open Access Journals (Sweden)

    Samanta Cristina das Chagas Xavier

    2014-05-01

    Full Text Available BACKGROUND: The new epidemiological scenario of orally transmitted Chagas disease that has emerged in Brazil, and mainly in the Amazon region, needs to be addressed with a new and systematic focus. Belém, the capital of Pará state, reports the highest number of acute Chagas disease (ACD cases associated with the consumption of açaí juice. METHODOLOGY/PRINCIPAL FINDINGS: The wild and domestic enzootic transmission cycles of Trypanosoma cruzi were evaluated in the two locations (Jurunas and Val-de Cães that report the majority of the autochthonous cases of ACD in Belém city. Moreover, we evaluated the enzootic cycle on the three islands that provide most of the açaí fruit that is consumed in these localities. We employed parasitological and serological tests throughout to evaluate infectivity competence and exposure to T. cruzi. In Val-de-Cães, no wild mammal presented positive parasitological tests, and 56% seroprevalence was observed, with low serological titers. Three of 14 triatomines were found to be infected (TcI. This unexpected epidemiological picture does not explain the high number of autochthonous ACD cases. In Jurunas, the cases of ACD could not be autochthonous because of the absence of any enzootic cycle of T. cruzi. In contrast, in the 3 island areas from which the açaí fruit originates, 66.7% of wild mammals and two dogs displayed positive hemocultures, and 15.6% of triatomines were found to be infected by T. cruzi. Genotyping by mini-exon gene and PCR-RFLP (1f8/Akw21I targeting revealed that the mammals and triatomines from the islands harbored TcI and Trypanosoma rangeli in single and mixed infections. CONCLUSION/SIGNIFICANCE: These findings show that cases of Chagas disease in the urban area of Belém may be derived from infected triatomines coming together with the açaí fruits from distant islands. We term this new epidemiological feature of Chagas disease as "Distantiae transmission".

  10. Phenotypic distance among assai palm’s mother plants (Euterpe oleracea Mart. from Eastern Amazon

    Directory of Open Access Journals (Sweden)

    Rosemiro Santos Galate

    2014-09-01

    Full Text Available The açai palm tree (Euterpe oleracea Mart. is native to the Amazonian estuary. Media revelation of the nutraceutical properties of açai palm has resulted in its introduction in the national and international markets, consequently increasing the açai palm crop area in the Amazon. Nevertheless, açai palm cultivation is performed in a rational manner, because of limited product extraction from the native açai palm varieties. The study aimed to conduct a preliminary estimate of genetic variability, parameters, and phenotypic divergence of parent açai palms. Data from 129 parent plants from northeast Pará was collected. Analysis of variance (ANOVA of 22 morphoagronomic traits was performed to estimate the genetic parameters. Divergence was estimated using standardized average euclidean distance by using unweighted pair group method with arithmetic mean (UPGMA and Tocher clustering methods. Significant variance was noted in 77.3% traits (ANOVA, p<0.01 and p<0.05; CVg/CVe ratio indicated that 72.3% traits may present genetic variability for use in breeding programs. The euclidean distance showed EO-070 and EO-072 parent plants (Combu Island as the least divergent, and EO-010 (Belém and EO-018 (Salinópolis as the most divergent. The clustering methods determined ten (Tocher and nine (UPGMA similar groups. The most dissimilar parent plants were EO-035 (Capitão Poço, EO- 109 (Combu Island, EO-019 (Salinópolis, and EO-010 (Belém (Tocher method, whereas even the EO-010 (Belém; EO-011 (São João de Pirabas; EO-017, EO-018, and EO-019 (Salinópolis; EO-062 and EO-109 (Combu Island plants showed dissimilarity. We concluded that the 129 mother plants have high phenotypic variability, indicating the possibility of their use in genetic breeding programs. Further, the divergent parent plants can be used in the production of genotypes with favorable characteristics.

  11. Synergistic inhibitory effect of hyperbaric oxygen combined with sorafenib on hepatoma cells.

    Directory of Open Access Journals (Sweden)

    Hai-Shan Peng

    Full Text Available OBJECTIVES: Hypoxia is a common phenomenon in solid tumors, associated with chemotherapy and radiotherapy resistance, recurrence and metastasis. Hyperbaric oxygen (HBO therapy can increase tissue oxygen pressure and content to prevent the resistance, recurrence and metastasis of cancer. Presently, Sorafenib is a first-line drug, targeted for hepatocellular carcinoma (HCC but effective in only a small portion of patients and can induce hypoxia. The purpose of this study is to investigate the effect of HBO in combination with sorafenib on hepatoma cells. METHODS: Hepatoma cell lines (BEL-7402 and SK-Hep1 were treated with HBO at 2 atmosphere absolute pressure for 80 min per day or combined with sorafenib or cisplatin. At different time points, cells were tested for cell growth, colony formation, apoptosis, cell cycle and migration. Finally, miRNA from the hepatoma cells was detected by microRNA array and validated by qRT-PCR. RESULTS: Although HBO, sorafenib or cisplatin alone could inhibit growth of hepatoma cells, HBO combined with sorafenib or cisplatin resulted in much greater synergistic growth inhibition (cell proliferation and colony formation in hepatoma cells. Similarly, the synergistic effect of HBO and sorafenib on induction of apoptosis was also observed in hepatoma cells. HBO induced G1 arrest in SK-Hep1 not in BEL-7402 cells, but enhanced cell cycle arrest induced by sorafenib in BEL-7402 treated cells. However, HBO had no obvious effect on the migration of hepatoma cells, and microRNA array analysis showed that hepatoma cells with HBO treatment had significantly different microRNA expression profiles from those with blank control. CONCLUSIONS: We show for the first time that HBO combined with sorafenib results in synergistic growth inhibition and apoptosis in hepatoma cells, suggesting a potential application of HBO combined with sorafenib in HCC patients. Additionally, we also show that HBO significantly altered microRNA expression

  12. Impact of target volume coverage with Radiation Therapy Oncology Group (RTOG) 98-05 guidelines for transrectal ultrasound guided permanent Iodine-125 prostate implants

    International Nuclear Information System (INIS)

    Horwitz, Eric M.; Mitra, Raj K.; Uzzo, Robert G.; Das, Indra J.; Pinover, Wayne H.; Hanlon, Alexandra L.; McNeeley, Shawn W.; Hanks, Gerald E.

    2003-01-01

    Purpose: Despite the wide use of permanent prostate implants for the treatment of early stage prostate cancer, there is no consensus for optimal pre-implant planning guidelines that results in maximal post-implant target coverage. The purpose of this study was to compare post-implant target volume coverage and dosimetry between patients treated before and after Radiation Therapy Oncology Group (RTOG) 98-05 guidelines were adopted using several dosimetric endpoints. Materials and methods: Ten consecutively treated patients before the adoption of the RTOG 98-05 planning guidelines were compared with ten consecutively treated patients after implementation of the guidelines. Pre-implant planning for patients treated pre-RTOG was based on the clinical target volume (CTV) defined by the pre-implant TRUS definition of the prostate. The CTV was expanded in each dimension according to RTOG 98-05 and defined as the planning target volume. The evaluation target volume was defined as the post-implant computed tomography definition of the prostate based on RTOG 98-05 protocol recommendations. Implant quality indicators included V 100 , V 90 , V 100 , and Coverage Index (CI). Results: The pre-RTOG median V 100 , V 90 , D 90 , and CI values were 82.8, 88.9%, 126.5 Gy, and 17.1, respectively. The median post-RTOG V 100 , V 90 , D 90 , and CI values were 96.0, 97.8%, 169.2 Gy, and 4.0, respectively. These differences were all statistically significant. Conclusions: Implementation of the RTOG 98-05 implant planning guidelines has increased coverage of the prostate by the prescription isodose lines compared with our previous technique, as indicated by post-implant dosimetry indices such as V 100 , V 90 , D 90 . The CI was also improved significantly with the protocol guidelines. Our data confirms the validity of the RTOG 98-05 implant guidelines for pre-implant planning as it relates to enlargement of the CTV to ensure adequate margin between the CTV and the prescription isodose

  13. Preliminary study of molecular imaging of human hepatocellular carcinoma xenograft with Gd-based MR probe containing arginine-glycine-aspartic acid chelate

    International Nuclear Information System (INIS)

    Huo Tianlong; Du Xiangke; Zhang Sen; Li Xubin; Liu Xia

    2008-01-01

    Objective: To develop a Gd-based MR probe containing arginine-glycine-aspartic acid (RGD) motif to reveal integrin αvβ3 receptor-expressed tumor. Methods: Commercially available HYNIC- RGD conjugate with co-ligand EDDA was labeled with GdCl 3 , and the mixture was isolated and purified by solid phase extract (SPE) to get the entire probe Gd-EDDA-HYNIC-RGD. Human HCC cell line BEL-7402 was cultured and the cells harvested and suspended then subcutaneously inoculated into athymic nude mice for tumor growth. In vitro cell binding assay to integrin αcβ3 receptor and cell viability experiments were conducted. Then in vivo, imaging of the three arms of xenografts were performed by MR scan with a dedicated animal coil at baseline and time points of 0, 30, 60, 90 minutes and 24 hour post-intravenous injection (p. i.) via the tail vein. Three arms of nude mice then were sacrificed for histological examination to confirm the imaging results. Results: Gd-EDDA-HYNIC-RGD was successfully isolated by SPE and validity was verified on signal enhancement through in vitro and in vivo experiments. The T 1 relaxation rate of the probe is 3.31 mmol/s; It is well tolerated to living cells when the concentration of the probe is below 0.1 μmol/ml; both BEL-7402 Human Hepatocellular Carcinoma cell line and the tumor expressed αvβ3 receptor; The RGD-ligand was observed specifically binding with αvβ3 receptor in vitro; The nude mice model bearing HHCC was well established. The signal intensity (SI) at the tumor site were 2247.6±39.0 at baseline and 2820.9±35.2 at 90 min p.i. respectively, the SI at 90 min increased less than 25% of baseline, which is statistically different (t=-38.031, P 0.05); The signal to time curve for probe-administrated group is straightforward over time in the span of 0 to 90 minute p.i. while the control arms do not show such tendency. Conclusion: Gd-EDDA-HYNIC-RGD has the potential to used as an MR probe detecting integrin αvβ3 receptor-expressed tumor

  14. Leishmania (Leishmania mexicana en el corregimiento de San Matías, municipio de Gómez Plata, Antioquia, Colombia

    Directory of Open Access Journals (Sweden)

    Diana Sierra

    2006-10-01

    Full Text Available Introducción. La leishmaniaisis es una enfermedad encontrada en focos naturales de infección donde están presentes insectos vectores y mamíferos reservorios deLeishmania. Objetivo. Registrar por primera vez la presencia de Leishmania (Leishmania mexicana Biagi, 1953, en el corregimiento de San Matías, municipio de Gómez Plata, departamento de Antioquia. Materiales y métodos. La especie fue aislada de un paciente con leishmaniasis cutánea localizada e identificada por la técnica de Inmunofluorescencia utilizando anticuerpos monoclonales específicos de especie y electroforesis de enzimas . Resultados y conclusión. Su perfil isoenzimático similar al de las cepas de referencia L. (L. mexicana (MNCY/BZ/62/M379 y L. (L. mexicana (MHOM/BE/82/BEL21, permitió concluír que la especie aislada del paciente es L. (L. mexicana.

  15. Synthesis and Biological Evaluation of Novel Furozan-Based Nitric Oxide-Releasing Derivatives of Oridonin as Potential Anti-Tumor Agents

    Directory of Open Access Journals (Sweden)

    Hao Cai

    2012-06-01

    Full Text Available To search for novel nitric oxide (NO releasing anti-tumor agents, a series of novel furoxan/oridonin hybrids were designed and synthesized. Firstly, the nitrate/nitrite levels in the cell lysates were tested by a Griess assay and the results showed that these furoxan-based NO-releasing derivatives could produce high levels of NO in vitro. Then the anti-proliferative activity of these hybrids against four human cancer cell lines was also determined, among which, 9h exhibited the most potential anti-tumor activity with IC50 values of 1.82 µM against K562, 1.81 µM against MGC-803 and 0.86 µM against Bel-7402, respectively. Preliminary structure-activity relationship was concluded based on the experimental data obtained. These results suggested that NO-donor/natural product hybrids may provide a promising approach for the discovery of novel anti-tumor agents.

  16. Traditional and silvipastoral system on Eastern Amazon - production and carcass and meat quality from buffaloSistemas silvipastoril e tradicional na Amazônia Oriental – produção e qualidade da carcaça e carne de búfalos

    Directory of Open Access Journals (Sweden)

    Maria Regina Sarkis Peixoto Joele

    2013-10-01

    Full Text Available The objective was to comparatively evaluate the physical and physico-chemical properties of buffaloes carcasses (Bubalus bubalis, Murrah/Mediterranean finished in Traditional System, with pasture and mineral supplements, with buffalo, from same race, finished in a Silvopastoral System, with mineral supplementation and diet composed of organic residues, in research unit of Embrapa Eastern Amazon, Belém, Para State, Brazil. The slaughter occurred in commercial slaughterhouse, following its normal flow, with quantitative and qualitative evaluations of the carcasses. The experimental design was randomized, with the data submitted to ANOVA and means compared using the ‘t’ test at 5% significance. Animals from Silvopastoral System slaughtered at weights similar to those of Traditional System in different ages, showed better carcass conformation and fat distribution, with significant differences (P Objetivou-se avaliar comparativamente as características físicas e físico-químicas das carcaças de búfalos (Bubalus bubalis, Murrah/Mediterrâneo, terminados em Sistema Tradicional, com pastagem cultivada e suplementação mineral, com animais terminados em Sistema Silvipastoril, com suplementação mineral e ração composta por resíduos agroindustriais, em Unidades de Pesquisa da Embrapa Amazônia Oriental, em Belém, Pará. Os abates ocorreram em abatedouro comercial, com posteriores avaliações quantitativas e qualitativas das carcaças. O delineamento experimental foi inteiramente casualizado, submetidos à análise de variância e médias comparadas pelo teste ‘t’, a 5% de significância. Os animais do Sistema Silvipastoril, abatidos com pesos similares aos do Sistema Tradicional, apresentaram melhor conformação de carcaça e acabamento de gordura, com diferenças significativas (P < 0,05 no marmoreio do músculo Longissimus dorsi e nos pesos de quartos traseiros, com aumento na produção de carnes nobres. Embora as carcaças tenham

  17. Half-life evaluations for 3H, 90Sr, and 90Y

    International Nuclear Information System (INIS)

    MacMahon, Desmond

    2006-01-01

    A recent paper has reviewed methods for the evaluation of discrepant sets of data and demonstrated the results of applying these methods to the published half-life data of 90 Sr and 137 Cs [MacMahon, T.D., Pearce, A., Harris, P., 2004. Convergence of techniques for the evaluation of discrepant data. Appl. Radiat. Isot. 60, 275-281]. The half-life data for 3 H has been subject to a comprehensive review and critical evaluation by Lucas and Unterweger [2000. Comprehensive review and critical evaluation of the half-life of tritium. J. Res. Natl. Inst. Stand. Technol. 105, 541-549]. The current paper reports the results of applying the various evaluation procedures of MacMahon et al. Convergence of techniques for the evaluation of discrepant data. Appl. Radiat. Isot. 60, 275-281] to the data of Lucas and Unterweger [Comprehensive review and critical evaluation of the half-life of tritium. J. Res. Natl. Inst. Stand. Technol. 105, 541-549], resulting in a recommended half-life of 4497(4) days. MacMahon et al. [Convergence of techniques for the evaluation of discrepant data. Appl. Radiat. Isot. 60, 275-281] highlighted problems in the evaluation of the discrepant half-life data of 90 Sr, in particular the worrying upward trend in the data, where the weighted mean of all the measurements increases, on average, by 35 days each time a new measurement result is added. The current paper reports on further analyses of these data. New measurements of the half-life of 90 Y have been reported by Kossert and Schrader [2004. Standardization by liquid scintillation counting and half-life measurements of 90 Y. Appl. Radiat. Isot. 60, 741]. This has prompted a new evaluation of all available published 90 Y half-life data. The data are fairly consistent, and a value of 64.063(16) h is recommended

  18. Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing

    OpenAIRE

    Romero-Hidalgo, Sandra; Ochoa-Leyva, Adrián; Garcíarrubio, Alejandro; Acuña-Alonzo, Victor; Antúnez-Argüelles, Erika; Balcazar-Quintero, Martha; Barquera-Lozano, Rodrigo; Carnevale, Alessandra; Cornejo-Granados, Fernanda; Fernández-López, Juan Carlos; García-Herrera, Rodrigo; García-Ortíz, Humberto; Granados-Silvestre, Ángeles; Granados, Julio; Guerrero-Romero, Fernando

    2017-01-01

    Understanding the genetic structure of Native American populations is important to clarify their diversity, demographic history, and to identify genetic factors relevant for biomedical traits. Here, we show a demographic history reconstruction from 12 Native American whole genomes belonging to six distinct ethnic groups representing the three main described genetic clusters of Mexico (Northern, Southern, and Maya). Effective population size estimates of all Native American groups remained bel...

  19. Nitrogen oxide suppression by using a new design of pulverized-coal burners

    Energy Technology Data Exchange (ETDEWEB)

    Kotler, V.R.; Cameron, S.D.; Grekhov, L.L. [All-Russian Thermal Engineering Institute, Moscow (Russian Federation)

    1996-07-01

    The results of testing a low-NO{sub x} swirl burner are presented. This burner was developed by Babcock Energy Ltd., for reducing nitrogen oxide emissions when burning Ekibastuz and Kuznetsk low-caking coals in power boilers. The tests conducted at a large plant of the BEL Technological Center showed that the new burner reduces NO{sub x} emissions by approximately two times. 6 refs., 6 figs., 1 tab.

  20. Understanding the Formation of the Rural in the Amazon Region

    Directory of Open Access Journals (Sweden)

    Cláudia de Souza

    2013-12-01

    Full Text Available COSTA, FRANCISCO DE ASSIS. Formação rural extrativista na Amazônia: os desafios do desenvolvimento capitalista - 1720-1970. Belém: NAEA, 2012. 154 páginas. (Coleção Economia Política da Amazônia. Série III – Formação Histórica; v.1. ISBN: 978-85-7143-102-7. Inclui bibliografias, fotos e gráficos.

  1. Area Handbook Series: Bolivia: A Country Study

    Science.gov (United States)

    1989-12-01

    sightseeing on the national railroad, and the Indian cultures. The government’s Boliv- ian Institute of Tourism (Instituto Boliviano de Turismo ...Colegio de Mexico, 1979. Zavaleta Mercado, Ren6 (ed.). Bolivia, hoy. Mexico City: Siglo Veintiuno Editores, 1983. -. Las masas en Novienbre. La Paz...123 Bel6im (Brazil), 148 Bolivian Institute of Tourism (Instituto Brz6 Hum~ez, Manuel Isidoro, xxviis, Boliviano de Turismo ), 149 20, 164 Bolivian

  2. Epistaksis

    OpenAIRE

    Munir, Delfitri; Haryono, Yuritna; Rambe, Andrina Y.M.

    2010-01-01

    Epistaxis is bleeding that comes out from nostril, nasal cavity and nasopharynx. Etiologies of epistaxis are local and systemic disorder. The most common sources of bleeding is Kiessel-bach’s plexus. Diagnostic is made by anamnesis, clinical examination, radiographs and laboratory. Management principles of epistaxis are stop bleeding, prevent complication and recurrent. Anterior epistaxis is stopped by cauterization and anterior packing while posterior epistaxis by posterior packing (Bel...

  3. Disainikaart : Brasiilia

    Index Scriptorium Estoniae

    2008-01-01

    Oscar Niemeyeri loodud ebamaiste skulpturaalsete vormidega hooned. Isay Weinfeldi, Sergio Rodrigues'e, Paulo Mendes da Rocha, Lucio Costa arhitektuurialane looming. Tootedisaini iseloomustab ehe materjalikasutus ja loodusressursse säästev disain, mida esindab Carlos Motta, Jose Zanine Caldas'e ja Joaquim Tenreiro disainitud mööbel.Modernistlik maastikuarhitekt Roberto Burle Marxi kujundatud park Ibirapuera, kunstnike Gilberto & Elisabethi puhas ja valge keraamika ning helilooja Caetano Veloso mitmekülgne kunstilooming

  4. An Investigation into the Social Context of Low-income, Urban Black and Latina Women: Implications for Adherence to Recommended Health Behaviors

    OpenAIRE

    2011-01-01

    Understanding factors that promote or prevent adherence to recommended health behaviors is essential for developing effective health programs, particularly among lower-income populations who carry a disproportionate burden of disease. We conducted in-depth qualitative interviews (n=64) with low-income Black and Latina women who shared the experience of requiring diagnostic follow-up after having an abnormal screening mammogram. In addition to holding negative and fatalistic cancer-related bel...

  5. An Investigation Into the Social Context of Low-Income, Urban Black and Latina Women

    OpenAIRE

    Shelton, Rachel C.; Goldman, Roberta E.; Emmons, Karen M.; Sorensen, Glorian; Allen, Jennifer D.

    2011-01-01

    Understanding factors that promote or prevent adherence to recommended health behaviors is essential for developing effective health programs, particularly among lower-income populations who carry a disproportionate burden of disease. We conducted in-depth qualitative interviews (n=64) with low-income Black and Latina women who shared the experience of requiring diagnostic follow-up after having an abnormal screening mammogram. In addition to holding negative and fatalistic cancer-related bel...

  6. IMPACTOS AMBIENTAIS DECORRENTES DO ATERRO SANITÁRIO DA REGIÃO METROPOLITANA DE BELÉM-PA: APLICAÇÃO DE FERRAMENTAS DE MELHORIA AMBIENTAL

    Directory of Open Access Journals (Sweden)

    Francinaldo Oliveira Matos

    2011-10-01

    Full Text Available A geração indiscriminada de Resíduos Sólidos (RS causa riscos ao equilíbrio ambiental e à saúde pública ao passo que é considerado como um dos problemas ambientais mais preponderantes na atualidade. Neste trabalho foi utilizado o método de Listagem de Controle (CHECK-LIST para identificar os principais impactos ambientais presentes no aterro sanitário do município de Belém-PA. Os resultados da pesquisa indicam deficiências no processo de gestão dos RS do município, principalmente no que tange à disposição final destes no aterro do Aurá onde foi constatado um alto potencial de contaminação do solo, do ar e dos recursos hídricos. Diante da inviabilidade de realocação da área propõem-se as seguintes medidas mitigadoras: ações de monitoramento da qualidade dos recursos ambientais, operação e manutenção de uma rede de drenagem de gás e a criação de um sistema de compostagem

  7. HCV INFECTION THROUGH PERFORATING AND CUTTING MATERIAL AMONG CANDIDATES FOR BLOOD DONATION IN BELÉM, BRAZILIAN AMAZON

    Directory of Open Access Journals (Sweden)

    Rubenilson Caldas Valois

    2014-12-01

    Full Text Available This study evaluated epidemiological factors for HCV infection associated with sharing perforating and cutting instruments among candidates for blood donation (CBD in the city of Belém, Pará, Brazilian Amazon. Two definitions of HCV infection cases were used: anti-HCV positivity shown by EIA, and HCV-RNA detection by PCR. Infected and uninfected CBD completed a questionnaire about possible risk factors associated with sharing perforating and cutting instruments. The information was evaluated using simple and multiple logistic regressions. Between May and November 2010, 146 (1.1% persons with anti-HCV antibodies and 106 (0.8% with HCV-RNA were detected among 13,772 CBD in Belém. Risk factors associated with HCV infection based on the EIA (model 1 and PCR (model 2 results were: use of needles and syringes sterilized at home; shared use of razors at home, sharing of disposable razors in barbershops, beauty salons etc.; and sharing manicure and pedicure material. The models of HCV infection associated with sharing perforating and cutting instruments should be taken into account by local and regional health authorities and by those of other countries with similar cultural practices, in order to provide useful information to guide political and public strategies to control HCV transmission.

  8. Latex of amapa (Parahancornia fasciculata (Poir Benoist, Apocynaceae: remedy and income in the forest and in the town

    Directory of Open Access Journals (Sweden)

    Murilo da Serra Silva

    2011-08-01

    Full Text Available The study investigated the production and trade chain as well as aspects of the consumption of the medicinal latex from amapa tree (Parahancornia fasciculata in the municipalities of Belém and Ponta de Pedras, State of Pará, Brazil. Our goal was to shed light upon several aspects related to the management and use of the product, revealing its importance to the life of producers and consumers. The approach used was the 'production to consumption chain' through qualitative and quantitative research methods, including market survey, interviews with extractivists, traders and consumers, workshops, guided visits and forest inventories. The eight thousand litters of milk sold annually in the Belém markets benefit especially the poor people, to whom the use of the 'amapa milk' is secular. The revenue from the latex represents 42% of the total income from non timber forest products for the tappers. The large number of individuals and the J-shaped diameter distribution of trees suggest the possibility of its natural regeneration. The improvement of the tapping technique reveals that the extractivists have knowledge on the tree anatomy. The tradition in the use and management of amapa milk as well as the ecological characteristics of the species indicates a good potential for programs on its sustainable production.

  9. Técnica dramática y retórica de las pasiones en el Tratado completo del arte del canto de Manuel García

    Directory of Open Access Journals (Sweden)

    Díaz Marroquín, Lucía

    2007-12-01

    Full Text Available The history of European singing technique, from the Italian origins of the stile rappresentativo and the early Seicento musical drama to the heights of bel canto, seems inextricably related to the classical rhetorical and philosophical theories, later re-interpreted by the humanist and rationalist authors. Manuel García’s Tratado completo del arte del canto inherits this tradition and contributes to it with every single observation or musical example included in this eminently practical work.

    Desde los orígenes italianos del stile rappresentativo y del drama musical, en los últimos años del siglo XVI y primeros del XVII, hasta el esplendor del bel canto, la historia de los tratados de canto europeos se encuentra inseparablemente asociada a las teorías retóricas y filosóficas clásicas, más tarde reinterpretadas por los autores humanistas y preenciclopedistas. Al escribir su Tratado completo del arte del canto, una obra eminentemente práctica, Manuel García hereda esta tradición y contribuye a ella con cada una de las observaciones y ejemplos musicales que propone.

  10. Eestis toodetud ilu / Kristel Kirss

    Index Scriptorium Estoniae

    Kirss, Kristel, 1967-

    2008-01-01

    Valik Eesti väljapanekutest mais 2008 Eesti Näituste Pirita messikeskuses toimunud messilt "Interjöör 2008": OÜ Valley lammastega vaip ja mängumuruga tumbad (disainerid Ruth Vassel, Luule Aasma), istumispadjad (tekstiilikunstnikud Liisa Tomasberg, Liisa Kallam), kõlarid (disainer Aleksandr Gorodenkov, nahatükkidest tumba ja lastemööbel (disainer Ingeborg Ahlberg), iste "Põder" (disainer Sirli Ehari), OÜ Seos jonnipunn-tool (disainer Merike Rehepapp), OÜ Resvok lesimisase "Lazy" (disainer Tõnis Krik)

  11. The broad line region of AGN: Kinematics and physics

    Directory of Open Access Journals (Sweden)

    Popović L.Č.

    2006-01-01

    Full Text Available In this paper a discussion of kinematics and physics of the Broad Line Region (BLR is given. The possible physical conditions in the BLR and problems in determination of the physical parameters (electron temperature and density are considered. Moreover, one analyses the geometry of the BLR and the probability that (at least a fraction of the radiation in the Broad Emission Lines (BELs originates from a relativistic accretion disk.

  12. CALS Test Network Handbook

    Science.gov (United States)

    1993-03-01

    Ltd Gillette Company Dorset, England Boston MA Foreign Broadcast Information Set. Giordano Associates Inc Frederick MD Long Branch NJ Formtek Inc...Associates Orem UT College Park MD InfoDesign Corp Johns Hopkins University Toronto, Ontario Laurel MD Information Spectrum Inc Joint Committee on Printing...Inc Washington DC Bel Air MD Navy Naval Research Laboratory OutSource Inc Washington DC Los Angeles CA 22 i +’ . S.. . -- -,•w• -- w,,Wmwmm mm -- m mmm

  13. Improving Bone Formation in a Rat Femur Segmental Defect by Controlling Bone Morphogenetic Protein-2 Release

    Science.gov (United States)

    2011-04-01

    of rhBMP-2 in patients.8 Both the physical properties and pharmacokinetics of the FR +BMP scaffold are believed to contribute to its superior...scaffolds investigated in this study exhibit these key physical properties.28 Further, the observation of re- generated bone grown in direct contact with...Amit, Y., Arbel, R., Aro, H., Atar , D., Bishay, M., Borner, M.G., Chiron, P., Choong, P., Cinats, J., Courtenay, B., Fei- bel, R., Geulette, B., Gravel

  14. A BRIEF STUDY ABOUT THE LEGAL NATURE OF PRECAUTIONA RY PRISONS (? IN BRAZILIAN CRIMINAL PROCESS

    Directory of Open Access Journals (Sweden)

    Tatiana Paula Cruz de Siqueira

    2015-12-01

    Full Text Available This article analyzes, even if soon, the legal nature of prison said as precautionary, that occur during the police investigation or criminal process. Over this study, prison in the act, preventive prison, according to each of its assumptions and, lastly, temporary prison will bel analyzed. At the end, will be presented the measures, which are effectively considered precautionary, serving to the utility of the final provision, like security measures

  15. Legendaarsed toolid Eesti Rahva Muuseumis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2005-01-01

    Tartu Kõrgema Kunstikooli mööbliosakonna loodud ja ennistatud mööbli näitus "Mööbel. Uksed. Pööning. Vanad tehnikad ja uus elu" Eesti Rahva Muuseumi näitusemajas. Näha saab Kölni messil auhinnatud Priit Verlini kujundatud istet "Allegro", esemeid Leonhard Vene ajaloolise mööbli kogust, Viini mööblikujundaja Koloman Moseri "dr Z-le" loodud ja Tartu ekspertide poolt restaureeritud tooli

  16. Report to the CCT on COOMET comparison COOMET.T-K3.1 (previously COOMET.T-S1): Key regional comparison of the national standards of temperature in the range from the triple point of water to the freezing point of zinc

    Science.gov (United States)

    Pokhodun, A. I.

    2010-01-01

    In the framework of the CIPM MRA, a first COOMET comparison "Comparison of the ITS-90 realizations in the range from 0.01 °C to 429.7485 °C (from the triple point of water to the freezing point of zinc)", registered in the KCDB under the identifier "COOMET.T-K3", was carried out in 2005-2007. Four national metrology institutes took part in this comparison: VNIIM (Russian Federation), SMU (Slovakia), BelGIM (Republic of Belarus) and NSC IM (Ukraine), and two of them (VNIIM and SMU) ensured the linkage with key comparisons CCT-K3 and CCT-K4, in order to disseminate the metrological equivalence to the measurement standards of NSC IM and BelGIM. NSC IM, however, had to withdraw its results, and at the meeting of Technical Committee T-10 of COOMET it was decided to carry out a supplementary bilateral comparison between VNIIM and the NSC IM for realization of the ITS-90 in the same range of temperature. This was registered in the KCDB under the identifier COOMET.T-S1 and measurements were performed in 2008-2009. From the results presented in this report, it is possible to draw the conclusion that the COOMET supplementary comparison COOMET.T-S1 demonstrates the CMC uncertainties claimed by the NSC IM for the melting point of gallium 0.236 mK (k = 2), and the freezing points of indium 1.040 mK (k = 2), tin 0.858 mK (k = 2) and zinc 0.944 mK (k = 2). In September 2012 the Working Group on key Comparisons (WG 7) of the CCT upgraded this comparison to a COOMET key comparison of the 'CCT-K3' type. It is now identified as COOMET.T-K3.1. In April 2013 this report was superseded by item 03006 in the Technical Supplement of 2013. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  17. Incidência de insetos e doenças em cultivares e populações de cebola Incidence of insects and diseases in onion cultivars and populations

    Directory of Open Access Journals (Sweden)

    Germano LD Leite

    2007-03-01

    Full Text Available A cebola é uma das hortaliças mais importantes no Brasil. Contudo, é atacada por insetos e doenças, tais como Thrips tabaci Lindeman, Botrytis squamosa, Alternaria porri e Colletotrichum gloeosporioides f.sp. cepae. Este trabalho teve como objetivo avaliar a incidência de tripes, queima-das-pontas, mancha-de-alternaria e mal-de-sete-voltas em oito populações elite do programa de melhoramento genético de cebola da Embrapa ("CNPH 6415", "CNPH 6074", "CNPH 6244", "CNPH 6400 Chata", "CNPH 6400 Redonda", "Valencianita" x "Aurora", "Primavera" x "Pera Norte" e "Pera Norte" x "Primavera" e oito variedades comerciais (Granex 429, BRS Cascata, Belém IPA 9, Crioula Alto Vale, Bola Precoce, Primavera, Régia e 1015 Y. Em regiões de alta incidência de C. gloeosporioides, os materiais recomendados são "CNPH 6415", "CNPH 6074" e "CNPH 6244"; de A. porri são "CNPH 6415", "CNPH 6074", "CNPH 6244", "BRS Cascata", "Valencianita" x "Aurora", "Primavera" x "Pera Norte", "Belém IPA 9", "Bola Precoce", "Primavera" e "Régia"; e de T. tabaci são "CNPH 6415", "CNPH 6074", "Granex 429", "Bola Precoce", "Primavera" e "Régia". As populações "CNPH 6415" e "CNPH 6074" apresentam resistência a esses três agentes etiológicos. Por outro lado, "CNPH 6400 Chata", "CNPH 6400 Redonda" e "1015 Y" são suscetíveis a C. gloeosporioides, A. porri e T. tabaci. Todos os materiais estudados sofrem ataque considerável de B. squamosa.Onion (Allium cepa L. is one of the most important vegetable crops in Brazil. It is attacked by insects and diseases, such as Thrips tabaci Lindeman (Thysanoptera: Thripidae, Botrytis squamosa (J.C. Walker, Alternaria porri (Ellis and Colletotrichum gloeosporioides f.sp. cepae Penz. This work evaluated the incidence of thrips, onion leaf blight, purple blotch, and smudge in eight elite populations of the Embrapa's onion breeding program ("CNPH 6415", "CNPH 6074", "CNPH 6244", "CNPH 6400 Chata", "CNPH 6400 Redonda", "Valencianita" x

  18. Mytedrab: Intet belæg for stigning i brug af steroider

    DEFF Research Database (Denmark)

    Vinther, Anders Schmidt; Vest Christiansen, Ask

    2017-01-01

    Ifølge medierne og nogle eksperter er steroidforbruget et stigende problem, som gerne skal tackles hurtigst muligt. Men når man gransker tallene, er det svært at finde evidens, der understøtter den påstand, skriver to forskere......Ifølge medierne og nogle eksperter er steroidforbruget et stigende problem, som gerne skal tackles hurtigst muligt. Men når man gransker tallene, er det svært at finde evidens, der understøtter den påstand, skriver to forskere...

  19. Zlo igrajet belõmi figurami i võigrõvajet / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2008-01-01

    Austria režissööri Michael Haneke 1997. aastal valminud psühhodraama "Jõhkrad mängud" ("Funny Games") Ameerikas sama lavastaja käe all valminud uusversioon ("Funny Games U.S") : Ameerika Ühendriigid 2007

  20. Farm Shop : Augmenter l'accès aux matières premières agricoles au ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Farm Shop est un modèle de franchise social novateur qui permet d'obtenir des matières premières d'excellente qualité à des prix abordables grâce à des économies d'échelle. Il forme également des franchisés et des agriculteurs sur la façon d'utiliser les matières premières. Au cours de ses trois premières années ...

  1. A contribuição de Henri Lefebvre para reflexão do espaço urbano da Amazônia

    Directory of Open Access Journals (Sweden)

    Charles Benedito Gemaque Souza

    2009-03-01

    Full Text Available L'espace considéré comme historiquement produit par l'homme dans le fait d'organiser tant politique qu'économiquement sa société; c'est l'afirmation qui distingue les oeuvres de Henri Lefebvre. Il s'occupe d'un essai concret de retourner à dialetique de Marx, mais sans le dogmatisme et les oppressions qui sont caractéristique d'autres interprétations de matérialiste. Pourtant, le présent de la réflexion de cet auteur inhérente à l' urbanisation de l'espace amazonique et dans l'attribution avec son espace social présent dans le quotidien de Belém permet l'exercice de la reconnaissance de validité d'une telle pensée avec l’appehension de la complexité de la ville dans l’Amazonie.The space considered as historically produced by man in organizing both political and economical his society; this is the affirmation that distinguishes Henri Lefebvre masterpieces. It deals with a concrete attempt in returning to the Marx dialectic, but without the dogmatism the characteristic oppressions concerning other materialist interpretations. However, the present time of the actor reflection inherent to the Amazon urban space and in assignment with its socio-spatial presented in Belém day-to-day allows the exercise of the validity acknowledgment of such thought along with apprehension of the Amazon city complexity.O espaço considerado como historicamente produzido pelo homem à medida que organiza política e economicamente a sua sociedade, esta é a afirmação que distingue o conjunto das obras de Henri Lefebvre. Trata-se de uma tentativa concreta de retornar à dialética de Marx, contudo sem os dogmatismos e as opressões características de outras interpretações marxistas. Nessa acepção, a atualidade das reflexões do autor em relação à realidade do contexto urbano na Amazônia e, designadamente, com as contradições espaciais presentes no cotidiano de Belém permite um exercício de reconhecimento da validade deste pensamento

  2. Cardiotonic agent milrinone stimulates resorption in rodent bone organ culture.

    OpenAIRE

    Krieger, N S; Stappenbeck, T S; Stern, P H

    1987-01-01

    The cardiotonic agent amrinone inhibits bone resorption in vitro. Milrinone, an amrinone analog, is a more potent cardiotonic agent with lower toxicity. In contrast to amrinone, milrinone stimulated resorption in cultures of neonatal mouse calvaria and fetal rat limb bones. Threshold doses were 0.1 microM in calvaria and 0.1 mM in limb bones; maximal stimulation occurred in calvaria at 0.1 mM. Maximal responses to milrinone and parathyroid hormone were comparable. Milrinone concentrations bel...

  3. People having global patent with a novel idea

    International Nuclear Information System (INIS)

    Wang, Yeon Jung

    1991-04-01

    This book introduces the people gotten global patent with a brilliant idea, the contents of this book are coca cola bottles of Lud, barbed-wire fence of Joseph, cross head of Phillip, a pencil attached a eraser of Heimann, blue jeans of Strauss, refining process of Martin whole, automobile of Daimler, artificial silk of Chardonnay, phone of Bel, a telegraphic instrument of Mos, streptomycin of Waksman, cement of Smitten, permanent machine of Haris and mickey mouse.

  4. Impact of health legislation on the sale of anorectics in a city in the Amazon region

    OpenAIRE

    Castro,Luana Valéria da Silva; Farias Junior,Gilvo; Teixeira,Francisco Martins; Vieira,José Ricardo dos Santos; Maia,Cristiane do Socorro Ferraz

    2012-01-01

    OBJECTIVES: The International Narcotics Control Board released its 2005 annual report, highlighting the Brazil population as one of the largest consumers of anorectics. In Brazil, the National Health Surveillance Agency issued the resolution RDC 58/2007 in order to control the prescription and sale of such drugs. In Belém, the biggest city in the Brazilian Amazon region, this resolution came into force in 2008, leading to inspections of drugstores and magistral pharmacies. The aim of this wor...

  5. People having global patent with a novel idea

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yeon Jung

    1991-04-15

    This book introduces the people gotten global patent with a brilliant idea, the contents of this book are coca cola bottles of Lud, barbed-wire fence of Joseph, cross head of Phillip, a pencil attached a eraser of Heimann, blue jeans of Strauss, refining process of Martin whole, automobile of Daimler, artificial silk of Chardonnay, phone of Bel, a telegraphic instrument of Mos, streptomycin of Waksman, cement of Smitten, permanent machine of Haris and mickey mouse.

  6. Sexuality through the eyes of the elderly.

    OpenAIRE

    Uchôa,Yasmim da Silva; Costa,Dayara Carla Amaral da; Silva Junior,Ivan Arnaldo Pamplona da; Silva,Saulo de Tarso Saldanha Eremita de; Freitas,Wiviane Maria Torres de Matos; Soares,Soanne Chyara da Silva

    2016-01-01

    Abstract Objective: to identify the perception of elderly persons about sexuality. Methods: a quantitative, observational and analytical cross-sectional study was performed in an institution specializing in elderly care in Belém, in the state of Pará. A questionnaire, produced by the authors, was applied to 200 elderly persons, aiming to identify issues related to sexuality both in their youth and today, as well as stimulant strategies and sexuality inhibiting factors among the elderly, amo...

  7. Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives

    Directory of Open Access Journals (Sweden)

    Wen-Xi Cai

    2016-01-01

    Full Text Available A series of novel 2-phenyl-4-trifluoromethyl thiazole-5-carboxamide derivatives have been synthesized and evaluated for their anticancer activity against A-549, Bel7402, and HCT-8 cell lines. Among the tested compounds, highest activity (48% was achieved with the 4-chloro-2-methylphenyl amido substituted thiazole containing the 2-chlorophenyl group on the two position of the heterocyclic ring. Other structurally similar compounds displayed moderate activity. The key intermediates have been fully characterized.

  8. Véhicules autonomes et environnement semi-statiques

    OpenAIRE

    Bellicot , Iker

    2006-01-01

    voir basilic : http://emotion.inrialpes.fr/bibemotion/2006/Bel06/ school: Universite Joseph Fourier; Les robots autonomes utilisent des balises (murs, coins en interieur ; arbres, batiments a l'exterieur) pour se localiser. Cependant cette localisation peut echouer si le robot confond les balises entre eux, ce qui peut arriver lorsque l'environnement change (dont l'exemple typique est le parking, pour lequel les voitures ne sont plus stationnees au meme endroit) ; l'imprecision du capteur peu...

  9. Record of Edessa scabriventris Stål (Hemiptera: Pentatomidae) associated to Eugenia uniflora (Brazilian-Cherry) and Psidium guajava (Guava) (Myrtaceae), in north-northeastern Brazil.

    Science.gov (United States)

    Lima, Mauricio S; Fernandes, José A M; Lima, Iracilda M M

    2010-01-01

    This study reports for the first time Edessa scabriventris Stål on Eugenia uniflora (Brazilian-cherry) and on Psidium guajava (guava) (Myrtaceae), fruit trees with economic value. Its geographic distribution is extended with records for the states of Alagoas (Maceió Municipality 35°45'11.16''W; 9°40'18.52''S) and Pará (Belém Municipality 48°28'14.65''W; 1°26'14.83''S), north-northeastern Brazil.

  10. Soliidne korter 'heas' majas / Anneliis Aunapuu

    Index Scriptorium Estoniae

    Aunapuu, Anneliis

    1998-01-01

    Kaks korterit on üheks liidetud. Sisearhitekt Taisi Kadarik on loonud kaasaegse interjööri, milles on tunda kolmekümnendate hõngu. Elu- ja söögituba eraldavad lükanduksed. Pehme mööbli valmistas T. Kadariku jooniste järgi PIN-Disain. Vaibad Peeter Kuutmalt. vitraaž Valev Seinalt. Köögis 'Snaidero' komplekt. Kappide liuguksed firmalt 'Rait Mööbel'. Magamis- ja vannitoast. Remondi eest vastutas firma 'Koger ja Sumberg'

  11. Combat Service Support Model Development: BRASS - TRANSLOG - Army 21

    Science.gov (United States)

    1984-07-01

    throughout’the system. Transitional problems may address specific hardware and related software , such as the Standard Army Ammunition System ( SAAS ...FILE. 00 Cabat Service Support Model Development .,PASS TRANSLOG -- ARMY 21 0 Contract Number DAAK11-84-D-0004 Task Order #1 DRAFT REPOkT July 1984 D...Armament Systems, Inc. 211 West Bel Air Avenue P.O. Box 158 Aberdeen, MD 21001 8 8 8 2 1 S CORMIT SERVICE SUPPORT MODEL DEVELOPMENT BRASS -- TRANSLOG

  12. The value of Growth Hacking. Business development manual for Emi-Rent Properties

    OpenAIRE

    Elezovic, Velimir

    2017-01-01

    This thesis was commissioned by Emi-Rent Properties, a real estate company based in Bel-grade, Serbia. The main objective of this thesis is to help determine the value of growth hack-er marketing for the case company’s newly commissioned marketing campaign. Secondary objective of this thesis is to present practical advice on the implementation of a successful marketing campaign with strong international aspects. The thesis will cover major marketing concepts and provide an alternative view by...

  13. The NATO Warsaw Summit: How to Strengthen Alliance Cohesion (Strategic Forum, Number 296)

    Science.gov (United States)

    2016-06-01

    notion of European disintegration—if it were to take hold—cannot have but the most profound im- plications for Alliance management. The rise of political...BEL SVN CAN DEU HRV NOR FRA ESP HUN GBR USA TUR DNK NLD CZE ROU PRT EST GRC LVA SVK LUX POL LTU Figure. NATO Defense Expenditure Data Source: Defence ...Danish Institute for International Studies, August 2015); Rainer L. Glatz and Martin Zapfe, NATO Defence Planning between Wales and Warsaw: Politico

  14. Evaluation in the Extreme : Research, Impact and Politics in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    17 sept. 2015 ... ​Depuis quelques décennies, on observe une augmentation du financement de la recherche dans les sociétés divisées par la violence et de la recherche menée sur ces sociétés. Mais comment savoir si la recherche a bel et bien une incidence sur ces sociétés ? Et, le cas échéant, cette incidence est-elle ...

  15. Res Publica v respublike / Roman Gornev

    Index Scriptorium Estoniae

    Gornev, Roman

    2002-01-01

    Järg 29. november nr. 48 lk. 7. Res Publica - uue poliitika partei. Res Publica Ida-Virumaal, partei juhtfiguurid, Res Publica Kohtla-Järvel. Koalitsioonileping Keskerakonnaga viis konfliktini partei juhtkonnaga. Kohtla-Järve Res Publica kohaliku organisatsiooni konflikti partei juhtkonnaga kommenteerib Hants Hint

  16. Preparation of 90Sr-90Y generator

    International Nuclear Information System (INIS)

    Jin Xiaohai; Yu Haibin; Zhang Jinming; Zhang Peixin; Lin Qiongfang

    1990-01-01

    In recent years, 90 Y has been considered as one of the best radionuclides for tumor radioimmunotherapy when chelated to tumor-associated antibodies. This evaluation is based on the superior properties of this radionuclide (suitable half-life, pure β-ray emitter of intermediate energy, stable daughters, and suitable chemical properties) and because it is available as a radionuclide generator product by decay of its 28a parent 90 Sr. The experimental conditions of 90 Sr- 90 Y generator are described. The elution efficiency of 90 Sr- 90 Y generator reaches 98%. One of the most important problems is the 90 Sr contamination breakthrough from the generator. The level of 90 Sr contamination must be controlled to the clinical standard. The cation exchange resin 732 (100-150 mesh) was successfully used for the separation of 90 Y from 90 Sr. The method used by the authors provides a 90 Y-HAc solution which is very simple and safe for administration to the patients. 90 Y was separated from 90 Sr almost completely, the level of the 90 Sr contamination per 740 MBq 90 Y product was only 0.74 kBq. However the toxicity of 90 Sr is extremely high, the human life-time permissible dose is 74 kBq, then 740 MBq of 90 Y is allowed to be administrated to a patient for 50-100 times

  17. Tripeptide tyroserleutide plus doxorubicin: therapeutic synergy and side effect attenuation

    International Nuclear Information System (INIS)

    Zhu, Zhi-feng; Yao, Zhi; Chen, Li-juan; Lu, Rong; Jia, Jing; Liang, Yu; Xu, Qiong; Zhou, Chun-lei; Wang, Li; Wang, Song

    2008-01-01

    Tripeptide tyroserleutide (YSL) is a novel small molecule anti-tumor polypeptide that has been shown to inhibit the growth of human liver cancer cells. In this study, we investigated the effects of YSL plus doxorubicin on the growth of human hepatocellular carcinoma BEL-7402 cells that had been transplanted into nude mice. Nude mice bearing human hepatocellular carcinoma BEL-7402 tumors were treated with successive intraperitoneal injections of saline; low-, mid-, or high-dose doxorubicin; or low-, mid-, or high-dose doxorubicin plus YSL. Effects on the weight and volume of the tumors were evaluated. Co-administration of YSL and high-dose doxorubicin (6 mg/kg every other day) prolonged the survival time of tumor-bearing mice as compared to high-dose doxorubicin alone. As well, the anti-tumor effects of mid- and low-dose doxorubicin (2 and 0.7 mg/kg every other day, respectively) were enhanced when supplemented with YSL; the tumor growth inhibition rates for YSL plus doxorubicin were greater than the inhibition rates for the same dosages of doxorubicin alone. The combination of YSL and doxorubicin decreased chemotherapy-associated weight loss, leukocyte depression, and heart, liver, and kidney damage as compared to doxorubicin alone. The combination of YSL plus doxorubicin enhances the anti-tumor effect and reduces the side effects associated with doxorubicin chemotherapy

  18. USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt.

    Science.gov (United States)

    Zhang, Jing; Luo, Nan; Tian, Yu; Li, Jiazhi; Yang, Xiaozhou; Yin, Huimin; Xiao, Congshu; Sheng, Jie; Li, Yang; Tang, Bo; Li, Rongkuan

    2017-04-11

    USP22, a member of the deubiquitinases (DUBs) family, is known to be a key subunit of the human Spt-Ada-Gcn5 acetyltransferase (hSAGA) transcriptional cofactor complex. Within hSAGA, USP22 removes ubiquitin from histone proteins, thus regulating the transcription and expression of downstream genes. USP22 plays important roles in many cancers; however, its effect and the mechanism underlying HCC chemoresistance remain unclear. In the present study, we found that USP22 was highly expressed in chemoresistant HCC tissues and cells and was correlated with the prognosis of HCC patients who received chemotherapy. Silencing USP22 in chemoresistant HCC Bel/Fu cells dramatically inhibited proliferation, migration, invasion and epithelial-mesenchymal transition in vitro; suppressed tumorigenic and metastatic capacities in vivo; and inhibited drug resistance-related proteins (MDR1, LRP, MRP1). Mechanistically, we found that USP22 knockdown exerts its function through down-regulating PI3K and activating Smad4, which inhibited phosphorylation of Akt. Silencing Smad4 blocked USP22 knockdown-induced Akt inhibition in Bel/Fu cells. Our results, for the first time, provide evidence that USP22 plays a critical role in the development of chemoresistant HCC cells and that high USP22 expression serves as a molecular marker for the prognosis of HCC patients who undergo chemotherapy.

  19. Effects of Uptake of Hydroxyapatite Nanoparticles into Hepatoma Cells on Cell Adhesion and Proliferation

    Directory of Open Access Journals (Sweden)

    Meizhen Yin

    2014-01-01

    Full Text Available Hydroxyapatite nanoparticles (nano-HAPs were prepared by homogeneous precipitation, and size distribution and morphology of these nanoparticles were determined by laser particle analysis and transmission electron microscopy, respectively. Nano-HAPs were uniformly distributed, with rod-like shapes sizes ranging from 44.6 to 86.8 nm. Attached overnight, suspended, and proliferating Bel-7402 cells were repeatedly incubated with nano-HAPs. Inverted microscopy, transmission electron microscopy, and fluorescence microscopy were used to observe the cell adhesion and growth, the culture medium containing nano-HAPs, the cell ultrastructure, and intracellular Ca2+ labeled with a fluo-3 calcium fluorescent probe. The results showed that nano-HAPs inhibited proliferation of Bel-7402 cells and, caused an obvious increase in the concentration of intracellular Ca2+, along with significant changes in the cell ultrastructure. Moreover, nano-HAPs led suspended cells and proliferating cells after trypsinized that did not attach to the bottom of the culture bottle died. Nano-HAPs continuously entered these cells. Attached, suspended, and proliferating cells endocytosed nano-HAPs, and nanoparticle-filled vesicles were in the cytoplasm. Therefore, hepatoma cellular uptake of nano-HAPs through endocytosis was very active and occurred continuously. Nano-HAPs affected proliferation and adhesion of hepatoma cells probably because uptake of nano-HAPs blocked integrin-mediated cell adhesion, which may have potential significance in inhibiting metastatic cancer cells to their target organ.

  20. Exceso de costos por sepsis intrahospitalaria en dos servicios de neonatología de Trujilo, Perú 2003-2005

    Directory of Open Access Journals (Sweden)

    Ruth A. Vargas-Gonzales

    2008-04-01

    Full Text Available Objetivos. Cuantificar el exceso de costos de la sepsis intrahospitalaria en los servicios de neonatología de dos hospitales del norte del Perú. Materiales y métodos. Se realizó un estudio de costos en el Hospital Belén y Regional Docente del Ministerio de Salud en Trujillo utilizando una metodología propuesta por la OPS. Se seleccionaron 141 casos con sepsis intrahospitalaria a partir de los registros del sistema de vigilancia de infecciones intrahospitalarias, contrastándose con neonatos hospitalizados sin sepsis durante el periodo 2003 - 2005. Los indicadores de costo utilizados fueron días-cama, uso de antimicrobianos traducido a dosis diarias definidas (DDD y número de hemocultivos. Resultados. El exceso de costos en tarifas subsidiadas por sepsis intrahospitalaria en neonatos del Hospital Regional Docente de Trujillo (n = 53 ascendió a US$ 7 580 por hospitalización, 408 por fármacos antimicrobianos y 144 por hemocultivos. En el Hospital Belén de Trujillo (n = 88 de US$ 15 997 por hospitalización, 733 en antibióticos y 914 en hemocultivos. Conclusiones. La sepsis intrahospitalaria neonatal genera un mayor costo al sistema, principalmente por días-cama. Se deben implementar adecuadamente programas de prevención para reducir los costos asociados y la morbimortalidad que producen.

  1. Planejamento de cardápios para escolas públicas municipais: reflexão e ilustração desse processo em duas capitais brasileiras

    Directory of Open Access Journals (Sweden)

    Cristine Garcia Gabriel

    2012-06-01

    Full Text Available Objetivos Refletir sobre o planejamento dos cardápios do Programa Nacional de Alimentação Escolar, e apresentar o procedimento em Florianópolis (SC e Belém (PA. MÉTODOS: Estudo transversal realizado por entrevistas com nutricionistas do Programa Nacional de Alimentação Escolar e análise de cardápios de 2010 da rede municipal de ensino fundamental. Utilizou-se como referência a Resolução nº38/2009, expedida pelo gestor federal do programa. RESULTADOS: Em Belém, encontraram-se cardápios padronizados para as escolas e baixa oferta de frutas/hortaliças; em Florianópolis, cardápios elaborados segundo critérios da gestão, conforme as particularidades das escolas, com maior oferta de frutas/hortaliças. Nas duas capitais, a utilização de alimentos regionais mostrou-se pequena, com ausência de compra direta de agricultores familiares. CONCLUSÃO: Observaram-se muitas peculiaridades nas capitais, refletindo a diversidade na execução do programa após a municipalização. Apontam-se a necessidade de maior inclusão de alimentos regionais nos cardápios e a efetivação de instrumentos legais que viabilizem a entrada dos pequenos produtores locais no mercado.

  2. DNA interaction, antioxidant activity, and bioactivity studies of two ruthenium(II) complexes

    Science.gov (United States)

    Han, Bing-Jie; Jiang, Guang-Bin; Yao, Jun-Hua; Li, Wei; Wang, Ji; Huang, Hong-Liang; Liu, Yun-Jun

    2015-01-01

    Two new ruthenium(II) polypyridyl complexes [Ru(dmb)2(dcdppz)](ClO4)2 (1) and [Ru(bpy)2(dcdppz)](ClO4)2 (2) were prepared and characterized. The crystal structure of the complex 2 was solved by single crystal X-ray diffraction. The complex crystallizes in the monoclinic system, space group P21/n with a = 12.9622(14) Å, b = 17.1619(19) Å, c = 22.7210(3) Å, β = 100.930(2)°, R = 0.0536, Rω = 0.1111. The DNA-binding constants for complexes 1 and 2 were determined to be 1.92 × 105 (s = 1.72) and 2.24 × 105 (s = 1.86) M-1, respectively. The DNA-binding behaviors showed that complexes 1 and 2 interact with DNA by intercalative mode. The antioxidant activities of the ligand and the complexes were performed. Ligand, dcdppz, has no cytotoxicity against the selected cell lines. Complex 1 shows higher cytotoxicity than complex 2, but lower than cisplatin toward selected cell lines. The apoptosis and cell cycle arrest were investigated, and the apoptotic mechanism of BEL-7402 cells was studied by reactive oxygen species (ROS), mitochondrial membrane potential and western blot analysis. Complex 1 induces apoptosis in BEL-7402 cells through ROS-mediated mitochondrial dysfunction pathway and by regulating the expression of Bcl-2 family proteins.

  3. LEPREL1 Expression in Human Hepatocellular Carcinoma and Its Suppressor Role on Cell Proliferation

    Directory of Open Access Journals (Sweden)

    Jianguo Wang

    2013-01-01

    Full Text Available Background. Hepatocellular carcinoma (HCC is one of the most aggressive malignancies worldwide. It is characterized by its high invasive and metastatic potential. Leprecan-like 1 (LEPREL1 has been demonstrated to be downregulated in the HCC tissues in previous proteomics studies. The present study is aimed at a new understanding of LEPREL1 function in HCC. Methods. Quantitative RT-PCR, immunohistochemical analysis, and western blot analysis were used to evaluate the expression of LEPREL1 between the paired HCC tumor and nontumorous tissues. The biology function of LEPREL1 was investigated by Cell Counting Kit-8 (CCK8 assay and colony formation assay in HepG2 and Bel-7402 cells. Results. The levels of LEPREL1 mRNA and protein were significantly lower in the HCC tissues as compared to those of the nontumorous tissues. Reduced LEPREL1 expression was not associated with conventional clinical parameters of HCC. Overexpression of LEPREL1 in HepG2 and Bel-7402 cells inhibited cell proliferation (P<0.01 and colony formation (P<0.05. LEPREL1 suppressed tumor cell proliferation through regulation of the cell cycle by downregulation of cyclins. Conclusions. Clinical parameters analysis suggested that LEPREL1 was an independent factor in the development of HCC. The biology function experiments showed that LEPREL1 might serve as a potential tumor suppressor gene by inhibiting the HCC cell proliferation.

  4. Detection of enteroviruses in cases of neurological disorders in the State of Pará, Brazil

    Directory of Open Access Journals (Sweden)

    GOMES Maria de Lourdes Contente

    2001-01-01

    Full Text Available Eighty-one cerebrospinal fluid (CSF samples mainly from cases of aseptic meningitis and motor deficiency syndrome were sent to the Virology Section of Evandro Chagas Institute, Belém Pará, in the period of January 1995 to January 1996 in order to isolate viruses. All samples were inoculated onto HEp-2 cell culture and newborn mice, with negative results. The probability of isolating viruses by these methods is reduced because of the low concentration of viral particles in these specimens. In order to obtain more information about the etiology of these cases, a group of 23 samples were selected to be tested by a more sensitive technique than the virus isolation - the reverse transcription polymerase chain reaction (RT-PCR. Specific primers directed to conserved regions in the enterovirus genome were used, considering that this group of viruses is frequently associated with these neurological disorder. The age of the patients ranged from 1 to 55 years and nearly all of them lived in Belém, State of Pará, North of Brazil. Of 15 samples analyzed by RT PCR nine (60% were positive; of these, 6 (66.6% had motor deficiency and 3 (33.3% developed aseptic meningitis. These results show that it is important to investigate enterovirus as cause of these syndromes.

  5. Res Publica objedinjajetsja s Sojuzom Otetshestva

    Index Scriptorium Estoniae

    2006-01-01

    Res Publica ja Isamaaliidu liitumisel tekib uus erakond - Eesti Eest!. Ida-Viru Isamaaliidu ja Res Publica esimeeste Hans Pindre, Vladislav Ponjatovski ning Narva Res Publica endise liidri Nikolai Golubevi arvamused

  6. Neurological manifestations in individuals with HTLV-1-associated myelopathy/tropical spastic paraparesis in the Amazon.

    Science.gov (United States)

    Dias, G A S; Yoshikawa, G T; Koyama, R V L; Fujihara, S; Martins, L C S; Medeiros, R; Quaresma, J A S; Fuzii, H T

    2016-02-01

    A cross-sectional observational study was conducted. The aim was to analyze the clinical-functional profile of patients diagnosed with HTLV-1 (human T-lymphotropic virus type 1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in the Amazon region. Reference center for HTLV in the city of Belém, state of Pará, Brazil. Muscle strength, muscle tone, balance and the need for gait assistance among patients with HAM/TSP were evaluated. Among the 82 patients infected with HTLV-1, 27 (10 men and 17 women) were diagnosed with HAM/TSP. No statistically significant difference in muscle tone or strength was found between the lower limbs. Muscle weakness and spasticity were predominant in the proximal lower limbs. Patients with HAM/TSP are at a high risk of falls (P=0.03), and predominantly use either a cane or a crutch on one side as a gait-assistance device (P=0.02). Patients with HAM/TSP exhibit a similar clinical pattern of muscle weakness and spasticity, with a high risk of falls, requiring gait-assistance devices.

  7. Organization of the Topical Meeting on Tunable Solid State Lasers Held in North Falmouth, Massachusetts on 1-3 May 1989

    Science.gov (United States)

    1989-08-30

    p. 163) under 647 and 780-nm pumping. (p. 183) WB6 Growth and Characterization of Nd Doped Alumi- 2:15 PM nates and Gallates with the Melilite...Various phosphate glasses 14.5-15.1 Lithium- lanthanum phosphate glass 15.45 Lithium aluminium borate glass 16.4 118 TuB6-2 Alexandrite AI2.-. Cr.BeO...Salisbury SA 5108, Australia Summary The fluorescence spectrum of neodymium in BeL ( lanthanum beryllate) shows ?L reasonably strong line in the R-X

  8. Teachers’ beliefs about reading and use of reading strategies

    OpenAIRE

    VASILIKA RRAKU

    2014-01-01

    The aim of this article is to place the focus on teachers’ beliefs about reading and reading strategies to the purpose of emphasizing the im portance of reading strategies in the reading process. The method of study is analytic analysis of teachers’ beliefs obtained through ques tionnaires delivered to 18 English language teachers of elementary, secondary and high level education in the region of Saranda in lbania. The results of the study pointed to a great concordance between teach ers’ bel...

  9. La confección de pigmentos en la producción de cerámica arqueológica (La Aguada, Catamarca, Argentina)

    OpenAIRE

    Zalba, Patricia Eugenia; Zagorodny, Nora; Balesta, Bárbara; Morosi, Martín Eduardo

    2002-01-01

    En este trabajo se analizan muestras minerales clasificadas como "pigmentos" (Wolters F. m.s.) halladas en contextos funerarios en el cementerio de La Aguada (Depto. de Belén, Prov. de Catamarca). Este materialforma parte de la Colección Benjamín Muniz Barreto del Museo de La Plata. Las tumbas excavadas totalizan doscientas. En doce unidades de entierro se registraron diecisiete muestras de "pigmentos" presentando algunos de ellos, evidencias de haber sido amasados en forma de panes. Se reali...

  10. CARACTERIZACIÓN BROMATOLÓGICA Y MICROBIOLÓGICA DE CARNES PROCEDENTES DE ESPECIES DE ANIMALES REGIONALES DE LA AMAZONIA PERUANA PARA CONSUMO HUMANO

    OpenAIRE

    Lozano, Ronald; Pinedo, Weninger; Inga, Lylyams

    2012-01-01

    La investigación consistió en la caracterización bromatológica y determinación microbiológica de muestras de carnes procedentes de ocho especies de animales silvestres: huangana (Tayassu pecari), majaz o picuro (Agouti paca), sajino (Tayassu tajacu), venado colorado (Mazama americana), tapir (Tapirus terrestris), añuje (Dasyprota fuliginosa), ronsoco (Hydrochaeris hydrochaeris) y armadillo (Dasypus novemcinctus); en las localidades de Puerto Belén-Roya-Utucuro, Santa Rosa de Aguaytía, Santa L...

  11. Gregório Ronca and Ermanno Stradelli: navy officer and anthropologist in the Amazon

    OpenAIRE

    Cappelli, Vittorio; Universita’ Della Calabria

    2013-01-01

    The intervention is intended to describe, comment and compare the experiences of two Italian travellers in Amazonas between the Eighteenth and the Nineteenth Centuries. The explorations and acts of Ermanno Stradelli, ethnologist who was been living and working in Amazonas since 1879 to 1926, and the explorative mission of Gregorio Ronca, Italian Navy’s officer, who in 1904 travelled from the Antilles to the Guyanas and Amazonas, going up the Amazon from Belém to Manaus and Iquitos, in order t...

  12. Gregório Ronca and Ermanno Stradelli: navy officer and anthropologist in the Amazon

    OpenAIRE

    Cappelli, Vittorio

    2012-01-01

    The intervention is intended to describe, comment and compare the experiences of two Italian travellers in Amazonas between the Eighteenth and the Nineteenth Centuries. The explorations and acts of Ermanno Stradelli, ethnologist who was been living and working in Amazonas since 1879 to 1926, and the explorative mission of Gregorio Ronca, Italian Navy’s officer, who in 1904 travelled from the Antilles to the Guyanas and Amazonas, going up the Amazon from Belém to Manaus and Iquitos, in order t...

  13. Avaliação psicológica na DEAM: um estudo de caso de violência sexual infantil

    OpenAIRE

    Adelma Pimentel

    2010-01-01

    The article approaches the importance of the psychological evaluation and the restricted use of the resulted got with the use of the technical projective and the prisoners' interviews in the several unities of the penal system. The material was got during the collect for the research of the manliness and domestic violence in DEAM/Belém. The method is the study case in practice medicine. The procedures were accomplished at the police station in an appropriate room for the attendance, however u...

  14. Malmö Konsthögskola

    OpenAIRE

    Madsen, Agnes

    2018-01-01

    Projektet syftar till att ta itu med behovet av en ny konsthögskola i Malmö. Centralt beläget i det gamla men lovande industriområdet Nyhamnen står skolan en spännande framtid till mötes. This project aims to address the need for a new art school in Malmö. Centrally located in the old, overlooked industrial area of Malmö, I hope the building will add new life to the future urban district.

  15. ifo Konjunkturprognose 2016/2017: Aufschwung in Deutschland geht in die zweite Halbzeit

    OpenAIRE

    Wollmershäuser, Timo; Nierhaus, Wolfgang; Hristov, Nikolay; Berg, Tim Oliver; Breuer, Christian; Garnitz, Johanna; Grimme, Christian; Hristov, Atanas; Lehmann, Robert; Meister, Wolfgang; Reif, Magnus; Schröter, Felix; Steiner, Andreas; Wohlrabe, Klaus; Wolf, Anna

    2016-01-01

    Der robuste Aufschwung, in dem sich die deutsche Wirtschaft seit dem Jahr 2014 befindet, wird sich fortsetzen. Das ifo Institut rechnet mit einem Zuwachs des realen Bruttoinlandsprodukts von 1,8% im laufenden Jahr. Im Jahr 2017 beläuft sich der Anstieg voraussichtlich auf 1,6%. Damit wird sich die Produktionslücke weiter verringern und im nächsten Jahr wohl nahezu geschlossen sein. Da diese Gangart der Konjunktur insgesamt eher verhalten ist, zeichnen sich keine Überhitzungserscheinungen auf ...

  16. A VIVÊNCIA DO ESTRESSE PROFISSIONAL NA UNIDADE DE TERAPIA INTENSIVA: VOZES DE PROFISSIONAIS DE SAÚDE NO PARÁ.

    OpenAIRE

    Tyll, Milene de Andrade Gouvea

    2014-01-01

    O objetivo deste estudo foi compreender a vivência do estresse profissional nas Unidades de Terapia Intensiva de um Hospital de referência, para identificar os principais fatores que contribuem ao estresse ocupacional e identificar o impacto subjetivo das fontes de estresse sobre o profissional e seu trabalho. Trata-se de uma pesquisa qualitativa, cujo referencial metodológico foi a Teoria Fundamentada em Dados, desenvolvida em um hospital de referência na cidade de Belém, Pará...

  17. Structure of the secondary xylem of Aniba Aubl. species from the Brazilian Amazon

    Directory of Open Access Journals (Sweden)

    Cláudia Viana Urbinati

    2014-09-01

    Full Text Available The aim of this study was to characterize the wood of Aniba species from the Brazilian Amazon, on the basis of specimens in the wood collection of the Herbarium of the Museu Paraense Emílio Goeldi, in the city of Belém, Brazil. The species were found to present a homogeneous structure in the secondary xylem, as defined by the location of oil cells; the presence of tyloses and crystals; and singularities of the radial and axial parenchyma.

  18. Konstruktion av vertikaltransportör för materialhantering

    OpenAIRE

    Furu, Micke

    2012-01-01

    Rotab Rostfria Transportörer AB tillverkar och utvecklar material- och godshanteringsutrustning. Företaget levererar även kompletta materialhanteringslösningar i form av godshanteringsanläggningar som ofta består av transportband och paketeringsutrustning. Examensarbetets mål är att utveckla en vertikaltransportör som ska transportera gods mellan två transportband belägna på olika höjder, transporten ska kunna varieras mellan 1000 - 3000 mm. Transportören ska undvika de två stora nackdelarna ...

  19. Application of the RES methodology for identifying features, events and processes (FEPs) for near-field analysis of copper-steel canister

    International Nuclear Information System (INIS)

    Vieno, T.; Hautojaervi, A.; Raiko, H.; Ahonen, L.; Salo, J.P.

    1994-12-01

    Rock Engineering Systems (RES) is an approach to discover the important characteristics and interactions of a complex problem. Recently RES has been applied to identify features, events and processes (FEPs) for performance analysis of nuclear waste repositories. The RES methodology was applied to identify FEPs for the near-field analysis of the copper-steel canister for spent fuel disposal. The aims of the exercise were to learn and test the RES methodology and, secondly, to find out how much the results differ when RES is applied by two different groups on the same problem. A similar exercise was previously carried out by a SKB group. A total of 90 potentially significant FEPs were identified. The exercise showed that the RES methodology is a practicable tool to get a comprehensive and transparent picture of a complex problem. The approach is easy to learn and use. It reveals the important characteristics and interactions and organizes them in a format easy to understand. (9 refs., 5 figs., 3 tabs.)

  20. Hypoglycemic depression of RES function.

    Science.gov (United States)

    Buchanan, B J; Filkins, J P

    1976-07-01

    The intravascular removal rates of colloidal carbon and of biologically active endotoxin by the reticuloendothelial system (RES) were evaluated as a function of blood-glucose levels. There was a significant negative correlation of carbon clearance half time on blood glucose in both saline-treated and insulin-treated rats. Insulin hypoglycemia depressed RES carbon clearance with the maximal effect occurring at blood glucose values below 30 mg/dl. Insulin hypoglycemia also severely impaired the intravascular removal of endotoxin as evaluated by lethality bioassay in lead-sensitized rats. It is concluded that blood glucose may modulate RES phagocytic function and that the hypoglycemia of endotoxin shock may augment the shock state due to impairment of RES host defense clearance functions.

  1. Res Publica kogub uut hoogu / Andres Jalak

    Index Scriptorium Estoniae

    Jalak, Andres, 1953-

    2005-01-01

    Kommenteerides Res Publica senise esimehe ja endise peaministri Juhan Partsi ning uueks esimeheks valitud Taavi Veskimäe kõnet Res Publica üldkogul, väljendab Res Publica fraktsiooni aseesimees usku, et Res Publica juhtimisel suudetakse 2007. aasta parlamendivalimistel taastada tulevikku suunatud mõtlemisega valitsus

  2. Muotiblogien luksus

    OpenAIRE

    Hara, Maiju

    2012-01-01

    Fashion and luxury go well together in fashion blogs. Quality outfits and polished appearances play a significant role in popular Finnish blogs. Luxury products have become more accessible to the average consumer since blogs have become more and more popular. Blogs provide an image that anyone can consume and wear luxury brands and products. The aim of the study was to examine what kind of luxury can be found in fashion blogs. Is it superfluous materialism? Or is it a need and a desire to bel...

  3. Jaani kirik Peterburis = St. John's Church in St. Petersburg / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2011-01-01

    1860. a. Peterburis avatud Jaani kirikust (arhitekt Harald Julius von Bosse) ja neoromaani stiilis kirikuhoone taastamisest. Maja taastati väliselt oma ajaloolisel kujul, kuid interjöör loodi kaasaegseid vajadusi arvestades. Sisearhitekt Juta Lember, tema selgitused. Tellija: Eesti Kontsert. Projekteerijad: НИИ Спецпроектреставрация, E. J. Merkurjevi Arhitektuuribüroo. Eestis valmistati eritellimusel mööbel,saali valgustid, kirikuinventar. Projekt: 2005-2010, valmis: 2011

  4. Accessibility evaluation model to support decision-making in urban investments : the case of Santarém-Brazil

    OpenAIRE

    Ramos, Rui A. R.; Rodrigues, Daniel Souto; Tobias, Maisa

    2011-01-01

    The main goal of the paper is to present an accessibility evaluation model for the urban area of Santarém, in Brazil. Located midway between the larger cities of Belém and Manaus, Santarém plays a crucial role in the region of Lower Amazonia. The paper describes the research instruments, sampling method and data analysis proposed for mapping urban accessibility. Basic activities (education, health, services, leisure and commerce) provided by the city were used to identify the main key-destina...

  5. The TimBel synchronization board for time resolved experiments at synchrotron SOLEIL

    International Nuclear Information System (INIS)

    Ricaud, J.P.; Betinelli-Deck, P.; Bisou, J.; Elattaoui, X.; Laulhe, C.; Monteiro, P.; Nadolski, L.S.; Renaud, G.; Ravy, S.; Silly, M.; Sirotti, F.

    2012-01-01

    Time resolved experiments are one of the major services that synchrotrons can provide to scientists. The short, high frequency and regular flashes of synchrotron light are a fantastic tool to study the evolution of phenomena over time. To carry out time resolved experiments, beamlines need to synchronize their devices with these flashes of light with a jitter shorter than the pulse duration. For that purpose, Synchrotron SOLEIL has developed the TimBeL (Timing Beamlines) board fully interfaced to TANGO framework. The TimBeL system is a compact PCI board. It is made of a mother with one daughter board. All functions are performed inside a FPGA (Field Programmable Gate Array) implemented on the mother board. A PLX Technology chip is used to communicate with the compact PCI crate. To enable experiments to remain always synchronous with the same bunch of electrons, the storage ring clock (CLK-SR) and the radio frequency clock (CLK-RF) are provided by the machine to beamlines. These clocks are used inside the FPGA as main clocks for state machines. Because the jitter is too large on the FPGA outputs, a daughter board with a jitter cleaner has been added to the system. This board also provides delay lines for compensating time offsets by 10 ps steps. This paper presents the main features required by time resolved experiments and how we achieved our goals with the TimBeL board

  6. Disainmööbel Roche Bobois, kokteil sarmist ja romantikast / Reet Krause

    Index Scriptorium Estoniae

    Krause, Reet, 1967-

    2004-01-01

    Luksuslikku kodumööblit tootvast prantsuse firmast. Firma disainerid itaallased Paola Navone ja Massimo Iosa Ghini, Vladimir Kagan, Hans Hopper ja prantslased Jean Claude Magirard ja Sylvain Joly. Philippe Roche ja disainer Hans Hopperi kommentaar

  7. Arithmetical unit, interrupt hardware and input-output channel for the computer Bel

    International Nuclear Information System (INIS)

    Fyroe, Karl-Johan

    1969-01-01

    This thesis contains a description of a small general purpose computer using characters, variable word-length and two-address instructions and which is working in decimal (NBCD). We have realized three interruption lines with a fixed priority. The channel is selective and has generally access to the entire memory. Using slow IO-devices, time sharing is possible between the channel and the processor in the central memory buffer area. (author) [fr

  8. Beggar-thy-neighbor in Art Consumption: Evidence from the “Bel Paese”

    OpenAIRE

    Nadia Campaniello; Matteo Richiardi

    2011-01-01

    This paper contributes to the relatively underdeveloped empirical literature on the demand for culture, testing whether the existence of cultural goods located in one region increases the demand for cultural goods in other regions. The measurement of such spillovers is important to determine the efficient allocation of cultural resources. We develop an empirical test based on aggregate data on the demand and supply of tourism in twenty Italian regions, that we complement with survey data coll...

  9. Investigação de surto de sarampo no Estado do Pará na era da eliminação da doença no Brasil

    Directory of Open Access Journals (Sweden)

    Hiane Santos de Jesus

    2015-10-01

    Full Text Available Resumo Em 27 de julho de 2010, houve a notificação tardia de um resultado de IgM reagente para sarampo em Belém, Pará, Brasil, que gerou uma investigação epidemiológica e medidas de controle e prevenção. Foram encontrados mais dois casos confirmados, irmãos do primeiro caso, com clínica e período de incubação compatível com sarampo. Realizamos busca retrospectiva em hospitais e laboratórios, cujo caso suspeito fora o residente ou visitante do Pará, que entre 1o de maio de 2010 e 4 de agosto de 2010, tenha apresentado febre e exantema acompanhado de tosse e/ou coriza e/ou conjuntivite. Todos os casos identificados foram investigados via contato telefônico e/ou visitas domiciliares. Revisamos 183.854 fichas de atendimento, sendo identificados 56 (0,03% casos suspeitos. Aplicamos 2.535 doses de vacina tríplice viral distribuídas entre bloqueios e intensificações vacinais. Ocorreu um surto intradomiciliar de sarampo em Belém com detecção e isolamento de genótipo viral importado da Europa. Recomenda-se uma vigilância epidemiológica oportuna e sensível à detecção de casos suspeitos de sarampo e manutenção de coberturas vacinais altas.

  10. Polarization sensitive behaviour of the band-edge transitions in ReS2 and ReSe2 layered semiconductors

    International Nuclear Information System (INIS)

    Ho, C H; Lee, H W; Wu, C C

    2004-01-01

    The polarization sensitive behaviour of the band-edge transitions in ReS 2 and ReSe 2 layered compounds was studied using polarized-transmission and polarized-thermoreflectance (PTR) measurements with polarization angles from θ = 0 deg. (Evector parallel b-axis) to θ = 90 deg. (Evector perpendicular b-axis) at 300 K. The polarization dependence of the polarized energy gaps of ReS 2 and ReSe 2 shows a sinusoidal-like variation with respect to the angular change of the linearly polarized light. The angular dependences of the polarized energy gaps of ReS 2 and ReSe 2 were evaluated. The polarization sensitive behaviour of the band-edge excitons in rhenium disulfide and diselenide was characterized using angular dependent PTR measurements from θ = 0 deg. to 90 deg. The polarized transition intensities of the band-edge excitons (E 1 ex and E 2 ex ) of ReX 2 (X = S, Se) demonstrate a sinusoidal variation with respect to the angular change of the linearly polarized light. The angular dependence of the polarized transition probabilities of E 1 ex and E 2 ex is analysed. The polarization sensitive behaviours of ReX 2 (X = S, Se) layers are discussed

  11. Atomic-scale friction on stepped surfaces of ionic crystals.

    Science.gov (United States)

    Steiner, Pascal; Gnecco, Enrico; Krok, Franciszek; Budzioch, Janusz; Walczak, Lukasz; Konior, Jerzy; Szymonski, Marek; Meyer, Ernst

    2011-05-06

    We report on high-resolution friction force microscopy on a stepped NaCl(001) surface in ultrahigh vacuum. The measurements were performed on single cleavage step edges. When blunt tips are used, friction is found to increase while scanning both up and down a step edge. With atomically sharp tips, friction still increases upwards, but it decreases and even changes sign downwards. Our observations extend previous results obtained without resolving atomic features and are associated with the competition between the Schwöbel barrier and the asymmetric potential well accompanying the step edges.

  12. Commander manipulator scoops prestigious mulit-million pound BNFL contract

    International Nuclear Information System (INIS)

    Bailey, Andrew.

    1997-01-01

    Twenty-one Commander robotic arms are on order from INBIS (formerly Ricardo Hitec) and BNFL Engineering Limited (''BEL'', the engineering arm of parent company BNFL). The multi-million pound contract was won amid fierce competition from other well-known names in robotic engineering. The specially designed Commander manipulators will be engaged in remotely handling Intermediate Level Waste (ILW) in a suite of four BNFL ILW plants, which are currently either under construction or planned at Sellafield. The first Commander will delivered to BNFL's Sellafield Silo Emptying Project in January 1998. (Author)

  13. On the energy-momentum density of gravitational plane waves

    International Nuclear Information System (INIS)

    Dereli, T; Tucker, R W

    2004-01-01

    By embedding Einstein's original formulation of general relativity into a broader context, we show that a dynamic covariant description of gravitational stress-energy emerges naturally from a variational principle. A tensor T G is constructed from a contraction of the Bel tensor with a symmetric covariant second degree tensor field Φ and has a form analogous to the stress-energy tensor of the Maxwell field in an arbitrary spacetime. For plane-fronted gravitational waves helicity-2 polarized (graviton) states can be identified carrying non-zero energy and momentum

  14. Eesti Kindlustuse peahoone V korruse renoveerimine esindusruumideks / Aivar Habakukk

    Index Scriptorium Estoniae

    Habakukk, Aivar

    1998-01-01

    Lahendus on valminud vastavalt ajaloolaste Leo Gensi ja Toivo Tinti poolt koostatud eritingimustele. 1925. a. valminud hoones oli juba algselt V korrus kavandatud kõige esinduslikumana. Projekt nägi ette esinduslikkuse taastamise. Korrusele olid ette nähtud direktsiooni kabinetid ja esindusruumid koos abiruumidega. Projekt : Stuudio Habakukk & Kivi, 1997. Autorid Aivar Habakukk, Enn Kivi. Ehituse peatöövõtt : AS Gustaf. Restaureerimine : AS KAR Grupp. Mööbel : esindusruumides Kinnarps, Bengt Olof (AS Santor), tööruumides A & A.S.A.. Valgustid : Steel Line AS. Valmis 1998.

  15. Cytotoxic Metabolites from the Soil-Derived Fungus Exophiala Pisciphila

    Directory of Open Access Journals (Sweden)

    Xiu-Kun Lin

    2011-03-01

    Full Text Available A new polyketide compound 1 and a new naturally occurring chromone derivative 2, along with two known indole alkaloids 3–4 were characterized from the ethyl acetate extract of a soil-derived fungal strain, Exophiala pisciphila PHF-9. The structures of compounds 1–4 were established by detailed spectroscopic analysis and comparison with literature data. The absolute configuration of 1 was determined by a modified Mosher’s method. Compound 1 exhibited moderate cytotoxicity against A-549, Hela, PANC-28 and BEL-7402 cell lines.

  16. Surgery in World War II. Ophthalmology and Otolaryngology

    Science.gov (United States)

    1957-01-01

    l)liysicialus who had1( hadl less formIal t raimiig inl 01)11 t IlIanolo!g"y but who had liaad ext emisive exp~erience ill thle slpecialltY ill...otolarviigologic patitenit", examiniled. Basil -Jones lb rep~or’ted 7cases at a Royal Aust raliant Air Fomi’e field hospital. Not 01’ as thle d imseis...bel~ieved that. 25 percent of all nasal comphaitits could he explained Onl tilie basils of allergy. The reactions to dhust , plants, grasses, weteds

  17. Caracterização geoelétrica de área de curtume localizada no distrito industrial de Icoaraci, Bélem-Pará

    OpenAIRE

    Nunes, Lana Patrícia Martins; Luiz, José Gouvêa

    2006-01-01

    Foi desenvolvido um estudo da subsuperfície rasa para investigar a possibilidade de contaminação do subsolo por líquidos usados no tratamento de couros. O estudo foi realizado na área da indústria Couro do Norte, Bairro de Maracacuera, no Distrito Industrial de Icoaraci em Belém-PA. As metodologias geofísicas utilizadas foram: eletrorresistividade (na forma de imageamento e através de sondagens verticais), potencial espontâneo, eletromagnético (slingram) e radar de penetração no solo (GPR). A...

  18. Det halvt dolda

    OpenAIRE

    Åberg, Elina

    2015-01-01

    I projektet utformas ett hotell med 34 rum i utkanten av den lilla historiska staden Mariefred, som ligger vid Mälaren 65 km från Stockholm. Hotellet utgörs av en kvadratisk volym med tegelfasad och avfasat hörn, belägen på en platt tomt intill museijärnvägen. Staden domineras i fonden av Gripsholms slott, och hotellets placering underordnar sig slottet och bevarar viktiga siktlinjer. Programmet innehåller utöver centrala funktioner som hotellrum, lobby  och restaurang även en biosalong i bot...

  19. Costa Brava, los retos urbanísticos del turismo de masas: la huella de la ciudad jardín y algunos principios racionalistas en el tejido turístico de masas

    OpenAIRE

    Ramos Caravaca, Carolina

    2013-01-01

    Director: Joaquin Sabaté Bel El turismo de masas plantea un nuevo reto urbanístico a mitad del siglo XX. La Costa Brava adopta el modelo de ciudad jardín, utilizado durante el turismo de élite, e introduce aportaciones del Movimiento Moderno. La costa es un territorio de experimentación donde la ciudad jardín y el urbanismo moderno convergen. Pese a las dificultades de los primeros años de ensayo, los nuevos tejidos muestran parámetros propios, y la relación de los edificios con e...

  20. "Hvem er som jeg blandt Guder?"

    DEFF Research Database (Denmark)

    Holst, Søren

    2004-01-01

    En hymne fra Dødehavsrullerne beskriver en persons opstigning til himlen, hvor den pågældende får tildelt overmenneskelig indsigt, som giver ham autoritet til at belære sine tilhængere på jorden. Hymnen analyseres, og der foretages en kritisk gennemgang af Israel Knohls bog "The Messiah Before Je...... Jesus", som hævder at teksten skulle handle om et medlem af Qumran-menigheden, som blev dræbt i Jerusalem og senere hævdedes at være opstået fra de døde....

  1. RELIGIÓN E IMPERIALISMO: REPRESENTACIONES DEL MARXISMO EN LA REVISTA LIÇÕES BÍBLICAS DE LA IGLESIA ASAMBLEA DE DIOS DE BRASIL (1980-1990

    Directory of Open Access Journals (Sweden)

    André Dioney Fonseca

    2010-04-01

    Full Text Available Pocos estudios en la historia han intentado analizar las consideraciones de los liderazgos pentecostales sobre las teorías marxistas, o el socialismo y el comunismo. Así, el objetivo de este artículo es analizar a través de la revista Lições Bíblicas la preocupación de la Asamblea de Dios Ministerio Misión de Belén con el marxismo, en un momento en el que muchos países aún estaban ligados al bloque comunista del Este Europeo

  2. Kunsti salakäik : Kumu Kunstimuuseum = A secret art passage / Panu Lehtovuori

    Index Scriptorium Estoniae

    Lehtovuori, Panu, 1968-

    2006-01-01

    Kumu hoonest, selle suhtest linnaga, hilismodernistlikust muuseumist, kunsti ja muuseumihoone suhtest. Projekteerija: Arkkitehtitoimisto Vapaavuori OY. Arhitekt Pekka Vapaavuori. Kaasautorid: Johan Roman, Miikka Hirsimäki, Pia Sabelström, Marcus Uppmeier, Elina Juureva, Mika Väisänen, Sauli Luttinen (3D). Sisekujundus: Pia Sabelström. Mööbel: Pille Lausmäe, Sisustusarkkitehdit Gullsten-Inkinen. Maastik: DIA Arhitektuur OÜ. Konstruktor: Neoprojekt OÜ. Ehitusfirmad: AS Merko Ehitus, AS Eesti Ehitus. Võistlus 1994, valmis 2005. Kommentaar Pekka Vapaavuorilt. Ill.: II ja V korruse plaan, 2 värv. välis- ja 5 sisevaadet

  3. Memorias en conflicto alrededor del Museo arqueológico Gustavo Le Paige, en San Pedro de Atacama, Chile

    OpenAIRE

    Finola, Hugo Alberto

    2016-01-01

    Los conflictos sociales y étnicos que se produjeron durante las últimas tres décadas en el norte chileno erigen como uno de sus escenarios el museo construido por el sacerdote belga y las actividades que en él se realizan. La figura misma del P. Gustavo Le Paige muestra las diversas caras del conflictivo trabajo de la memoria de la comunidad. The social and ethnic conflicts that occurred during the last three decades in north of Chile stand as one of their scene the museum built by the Bel...

  4. Res Publica aps / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2003-01-01

    Autori sõnul tekitavad tänavatel ülesseatud postrid, kus peaminister Juhan Parts kutsub üles ütlema "jah" Euroopa Liidule, kummastust, sest ehkki on tegemist Res Publica kampaaniaga, on tavainimesel raske vahet teha valitsuse justkui neutraalse referendumikampaania ja Res Publica "jah"-kampaania vahel

  5. Strontium-82/rubidium-82 generator

    International Nuclear Information System (INIS)

    Gennaro, G.P.; Haney, P.S.

    1986-01-01

    Hydroxylapatite, a compound having the formula: M 10 (PO 4 ) 6 (OH) 2 wherein M is calcium, strontium, barium, lead, iron, sodium, potassium, zinc, cadmium, magnesium, aluminium or a rare earth metal, is provided as a support medium for strontium-82 in a strontium-82/rubidium-82 parent-daughter radionuclide generator

  6. Padenije Res Publica / Viktoria Jürmann

    Index Scriptorium Estoniae

    Jürmann, Viktoria

    2005-01-01

    Res Publica üks rajajatest, Rein Taagepera, lahkus parteist, süüdistades erakonda paremtsentristlikust maailmavaatest loobumises. Res Publica Riigikogu fraktsioon tahab avaldada umbusaldust haridus- ja teadusminister Mailis Repsile

  7. Lõhe Res Publicas / Eve Heinla

    Index Scriptorium Estoniae

    Heinla, Eve, 1966-

    2005-01-01

    Tallinna linnapea Tõnis Palts on vastu Tallinna volikogu Res Publica fraktsiooni esimehe Toomas Tautsi abikaasa Kristina Tautsi tööleasumisele Lääne-Tallinna keskhaigla haldusjuhina. T. Paltsi kirjast Res Publica Tallinna piirkonna juhatusele. Lisa: Kuidas lahvatas pealinna võimutüli. Kommenteerivad: Maret Maripuu, Tõnis Palts, Vladimir Maslov

  8. 10 teesi Res Publica valitsemisprogrammist aastani 2007

    Index Scriptorium Estoniae

    2004-01-01

    Ilmunud ka: Ottshjot narodu Estonii. Res Publica 2003, 2004, lk. 4-5, 8-9. Res Publica valitsemisprogrammi lubadustest ja täitmisest. Vt. lk. 8-9 Res Publica ministrite olulisemad tegevused 2004. aastal - lühiülevaate teevad Ken-Marti Vaher, Taavi Veskimägi, Marko Pomerants, Toivo Maimets

  9. Isamaaliidu ühinemisjutt ajas Res Publica keema / Toomas Sildam

    Index Scriptorium Estoniae

    Sildam, Toomas, 1961-

    2005-01-01

    Ilmunud ka: Postimees : na russkom jazõke 14. nov., lk 3. Isamaaliidu esimehe Tõnis Lukase ettepanekut Isamaaliidu ja Res Publica ühinemiseks pooldavad ka Res Publica eestseisuse liikmed Juhan Parts ja Tõnis Palts, kuid Res Publica esimehe Taavi Veskimäe kinnitusel läheb Res Publica 2007. aasta parlamendivalimistele vastu iseseisvalt. Lisa: Isamaaliit ja Res Publica

  10. Miks Res Publica kaotas / Juhan Parts

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 29. juuni 2004, lk. 2; Koit, 29. juuni 2004, lk. 6. Europarlamendi valimiste tulemused erakonnale Res Publica. Juhan Partsi kõne 26. juunil Pärnus toimunud Res Publica volikogul. Lühendatult

  11. Res Publica otsib kandepinda / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2004-01-01

    Res Publica peasekretäri Ott Lumi sõnul on erakond teinud tõsised järeldused Euroopa Parlamendi valimiste tulemusest. Res Publica parlamendifraktsiooni väljasõidul pidas kriitilise kõne erakonna esimees Juhan Parts

  12. In medias res

    DEFF Research Database (Denmark)

    Foote, Jonathan

    2017-01-01

    nor does he begin the Trojan War ab ovo (with the egg) but always he hurries to the action and snatches the listener in medias res (into the middle of things)      Horace, Ars Poetica 145–147 Good epic poets do not commence their tale from the beginning—ab ovo (with the egg)—as Horace states......, but rather descend in medias res (into the middle of things), a reference to the Illiad opening already many years into the Trojan War. Perhaps this sentiment of plunging into the middle of action was felt by researchers in 1976 when, upon the walls of the San Lorenzo New Sacristy in Florence, they uncovered...

  13. Screening agrochemicals as potential protectants of plants against ozone phytotoxicity

    International Nuclear Information System (INIS)

    Saitanis, Costas J.; Lekkas, Dimitrios V.; Agathokleous, Evgenios; Flouri, Fotini

    2015-01-01

    We tested seven contemporary agrochemicals as potential plant protectants against ozone phytotoxicity. In nine experiments, Bel-W3 tobacco plants were experienced weekly exposures to a) 80 nmol mol −1 of ozone-enriched or ozone-free air in controlled environment chambers, b) an urban air polluted area, and c) an agricultural-remote area. Ozone caused severe leaf injury, reduced chlorophylls' and total carotenoids' content, and negatively affected photosynthesis and stomatal conductance. Penconazole, (35% ± 8) hexaconazole (28% ± 5) and kresoxim-methyl (28% ± 15) showed higher plants’ protection (expressed as percentage; mean ± s.e.) against ozone, although the latter exhibited a high variability. Azoxystrobin (21% ± 15) showed lower protection efficacy and Benomyl (15% ± 9) even lower. Trifloxystrobin (7% ± 11) did not protect the plants at all. Acibenzolar-S-methyl + metalaxyl-M (Bion MX) (−6% ± 17) exhibited the higher variability and contrasting results: in some experiments it showed some protection while in others it intensified the ozone injury by causing phytotoxic symptoms on leaves, even in control plants. - Highlights: • Penconazole and hexaconazole offered some protection to plants against ozone. • Bion MX fungicide caused phytotoxic symptoms to Bel-W3 tobacco plants. • Stomatal conductance was reduced in ozone-fumigated plants. - Seven agrochemicals were assessed as potential protectants against ozone phytotoxicity – triazoles fungicides were the most effective

  14. The fishery of tamoatá Hoplosternum littorale (Hancock, 1828 (Siluriformes: Callichthyidae in the Marajó Island

    Directory of Open Access Journals (Sweden)

    Adna Almeida de Albuquerque

    2008-12-01

    Full Text Available Hoplosternum littorale (Hancock, 1828 (Siluriformes, Callichthyidae is a middle size catfish, known in the Brazilian Amazon as ‘tamoatá’. It uses an accessory air-breathing organ to live in the poor oxygen swamps of the mouth of Amazon and Orinoco rivers. The tamoatá is the main fishery resource of the Marajó Island and it is caught in the flooded savanna of the Arari River basin, near the Santa Cruz do Arari city, Pará State. The tamoatá landing in the port of Ver-o-Peso, in Belém, represents about 6% of the total fish landing. The tamoatá fishery is seasonal, occurring mainly in the dry season. The fishery occurs in the river and lake environments, during July and August, and moves to the pools in the farms, which are the last to be dried in the region, during October and November. People that live in the region also do the fishery, and they sell production to fishing boats sellers, called locally as ‘geleiras’. Those boats are made of wood and carry the fish in iceboxes. The fishes are sold at the ports of important cities, in special the Ver-o-Peso port. The fishery activity is here described based on the interviews with fishermen and local inhabitants. Along the period of this study, were registered 415 boats carrying the tamoatá to Belém. The icebox capacities in the boats were until to 27 tons. The fishery gears used were gillnet and seine net.

  15. Patterns of Bacterial and Archaeal Gene Expression through the Lower Amazon River

    Directory of Open Access Journals (Sweden)

    Brandon M. Satinsky

    2017-08-01

    Full Text Available Analysis of metatranscriptomic and metagenomic datasets from the lower reaches of the Amazon River between Óbidos and the river mouth revealed microbial transcript and gene pools dominated by Actinobacteria, Thaumarchaeota, Bacteroidetes, Acidobacteria, Betaproteobacteria, and Planctomycetes. Three mainstem stations spanning a 625 km reach had similar gene expression patterns (transcripts gene copy−1 across a diverse suite of element cycling genes, but two tributary-influenced stations at the mouth of the Tapajós River and near the Tocantins River at Belém had distinct transcriptome composition and expression ratios, particularly for genes encoding light-related energy capture (higher and iron acquisition and ammonia oxidation (lower. Environmental parameters that were useful predictors of gene expression ratios included concentrations of lignin phenols, suspended sediments, nitrate, phosphate, and particulate organic carbon and nitrogen. Similar to the gene expression data, these chemical properties reflected highly homogeneous mainstem stations punctuated by distinct tributary-influenced stations at Tapajós and Belém. Although heterotrophic processes were expected to dominate in the lower Amazon, transcripts from photosynthetic bacteria were abundant in tributary-influenced regions, and transcripts from Thaumarcheota taxa genetically capable of chemosynthetic ammonia oxidation accounted for up to 21% of the transcriptome at others. Based on regressions of transcript numbers against gene numbers, expression ratios of Thaumarchaeota populations were largely unchanged within the mainstem, suggesting a relatively minor role for gene regulation. These quantitative gene and transcript inventories detail a diverse array of energy acquisition strategies and metabolic capabilities for bacteria and archaea populations of the world's largest river system.

  16. Modos de apropriação do gênero debate regrado na escola: uma abordagem aplicada The production process of the genre debate in the mother language teaching and learning context: an applied approach

    Directory of Open Access Journals (Sweden)

    Sandoval Nonato Gomes-Santos

    2009-01-01

    Full Text Available Este estudo propõe descrever e analisar o processo de produção do gênero debate regrado, no contexto de práticas de ensino-aprendizagem de língua materna, em turmas de Ensino Médio de uma escola pública de Belém (PA. Trata-se de compreender os modos com que o gênero mencionado, instituído objeto de ensino, se disciplinariza, ou seja, o estatuto que adquire quando inscrito na ordem da disciplina escolar Língua Portuguesa. Para tanto, optamos por focalizar a atividade do aluno, mais especificamente os dispositivos pelos quais ele se inscreve no gênero ensinado, o que implica em considerar não apenas os modos com que se apropria do mesmo, mas suas percepções sobre a própria tarefa com que se acha envolvido.The genre debate has its own particular rules. This study describes and analyses the production process of the genre debate in the mother language teaching and learning context, in High School juniors groups of a public school in Belém (PA. The aim of the study is to understand how this genre, as a teaching object, assumes the role of discipline content, that is, its status in the Portuguese language class. Students' productions, specifically the roles they assume to perform in this genre, are focused on. This focus implies considering not only the ways in which students learn the genre, but also their perceptions about the tasks they are involved in achieving.

  17. Mucorales from the semiarid of Pernambuco, Brazil.

    Science.gov (United States)

    de Azevedo Santiago, André Luiz Cabral Monteiro; Dos Santos, Paulo Jorge Parreira; Maia, Leonor Costa

    2013-01-01

    Nineteen taxa of Mucorales, belonging to Absidia, Apophysomyces, Cunninghamella, Fennellomyces, Lichtheimia, Mucor, Mycotypha, Rhizopus and Syncephalastrum were isolated from 36 composite soil samples in three semiarid areas in the State of Pernambuco (Triunfo, Cabrobó and Belém de São Francisco), Northeast Brazil, which are characterized by Caatinga vegetation. Triunfo is preserved, whereas Cabroró and Belém de São Francisco are experiencing low and severe desertification processes, respectively. Mucorales were isolated in Petri dishes in triplicate from 5 mg samples of soil placed on the surface of wheat germ agar plus chloramphenicol and Cercobin [Dimethyl 4,49-(103 phenylene) bis (3-thioallophanate)] medium. The plates were left on a bench at room temperature (28 ± 2 °C) for 72 h of alternating dark and light periods. Absidia cylindrospora presented the highest amount of CFU/g of soil, followed by L. hyalospora, C. phaeospora and C. echinulata var. echinulata. The latter, and R. microsporus var. microsporus, presented the highest frequencies of occurrence. Soils from Triunfo showed higher diversity of Mucorales than the samples from the other areas, although without differing statistically in relation to species richness. The communities of Mucorales from the degraded areas were more similar, while that from the preserved area was quite different. Most of the identified specimens have been commonly isolated from soil in other Brazilian regions, which indicates that they are not endemic of the semiarid. Eleven taxa are registered for the first time in this ecosystem, while F. heterothallicus is reported for the first time in Brazil.

  18. Mucorales from the semiarid of Pernambuco, Brazil

    Directory of Open Access Journals (Sweden)

    André Luiz Cabral Monteiro de Azevedo Santiago

    2013-01-01

    Full Text Available Nineteen taxa of Mucorales, belonging to Absidi, Apophysomyces, Cunninghamella, Fennellomyces, Lichtheimi, Mucor, Mycotypha, Rhizopus and Syncephalastrum were isolated from 36 composite soil samples in three semiarid areas in the State of Pernambuco (Triunfo, Cabrobó and Belém de São Francisco, Northeast Brazil, which are characterized by Caatinga vegetation. Triunfo is preserved, whereas Cabroró and Belém de São Francisco are experiencing low and severe desertification processes, respectively. Mucorales were isolated in Petri dishes in triplicate from 5 mg samples of soil placed on the surface of wheat germ agar plus chloramphenicol and Cercobin [Dimethyl 4,49-(103 phenylene bis (3-thioallophanate] medium. The plates were left on a bench at room temperature (28 ± 2 ºC for 72 h of alternating dark and light periods. Absidia cylindrospora presented the highest amount of CFU/g of soil, followed by L. hyalospor, C. phaeospora and C. echinulata var. echinulata. The latter, and R. microsporus var. microsporus, presented the highest frequencies of occurrence. Soils from Triunfo showed higher diversity of Mucorales than the samples from the other areas, although without differing statistically in relation to species richness. The communities of Mucorales from the degraded areas were more similar, while that from the preserved area was quite different. Most of the identified specimens have been commonly isolated from soil in other Brazilian regions, which indicates that they are not endemic of the semiarid. Eleven taxa are registered for the first time in this ecosystem, while F. heterothallicus is reported for the first time in Brazil.

  19. Das Abordagens de Desenvolvimento aos Instrumentos de Planejamento e Gestão Urbanos: A Influência de Idéias Exógenas nos Planos Diretores Amazônicos

    Directory of Open Access Journals (Sweden)

    Tiago Veloso

    2012-06-01

    Full Text Available Na atualidade das políticas públicas para o espaço urbano no Brasil, tem sido criada uma normatização geral acerca da construção de instrumentos de planejamento e gestão urbana, constituídos especialmente no período pós-Constituição de 1988. A normatização dispõe acerca da obrigatoriedade de boa parte dos municípios brasileiros em construir seus instrumentos de planejamento e desenvolvimento urbano, notadamente o plano diretor. Nesse sentido, trata-se de compreender o processo de difusão das principais abordagens de desenvolvimento urbano, no contexto de estruturação de planos diretores municipais urbanos, analisando as cidades amazônicas pelo estudo de caso da conformação metropolitana de Belém a partir de suas duas principais cidades, Belém e Ananindeua. O estudo busca elucidar como a difusão dessas abordagens de desenvolvimento acontece na escala local, especialmente na construção de instrumentos de planejamento e gestão, como os planos diretores. Este estudo foi fundamentado teoricamente a partir da contribuição acerca das abordagens de desenvolvimento urbano de Souza (1998; 2000; 2002 e, do ponto de vista metodológico, adotou uma abordagem de pesquisa qualitativa, utilizando análise documental e dados primários provenientes de instituições de planejamento envolvidas no processo de difusão da agenda urbana na Amazônia.

  20. RES: Regularized Stochastic BFGS Algorithm

    Science.gov (United States)

    Mokhtari, Aryan; Ribeiro, Alejandro

    2014-12-01

    RES, a regularized stochastic version of the Broyden-Fletcher-Goldfarb-Shanno (BFGS) quasi-Newton method is proposed to solve convex optimization problems with stochastic objectives. The use of stochastic gradient descent algorithms is widespread, but the number of iterations required to approximate optimal arguments can be prohibitive in high dimensional problems. Application of second order methods, on the other hand, is impracticable because computation of objective function Hessian inverses incurs excessive computational cost. BFGS modifies gradient descent by introducing a Hessian approximation matrix computed from finite gradient differences. RES utilizes stochastic gradients in lieu of deterministic gradients for both, the determination of descent directions and the approximation of the objective function's curvature. Since stochastic gradients can be computed at manageable computational cost RES is realizable and retains the convergence rate advantages of its deterministic counterparts. Convergence results show that lower and upper bounds on the Hessian egeinvalues of the sample functions are sufficient to guarantee convergence to optimal arguments. Numerical experiments showcase reductions in convergence time relative to stochastic gradient descent algorithms and non-regularized stochastic versions of BFGS. An application of RES to the implementation of support vector machines is developed.

  1. Kes tegelikult lõid Res Publica? / Valeri Kalabugin

    Index Scriptorium Estoniae

    Kalabugin, Valeri

    2005-01-01

    Enne erakonnaks kuulutamist oli Res Publica Eesti iseseisvust ja demokraatiat taotlev ühendus, kuhu on kuulunud mitmed poliitika- ning ühiskonnategelased. Vt. samas: Ühendus Res Publica avaldus. Küsimustele vastavad Res Publica avalike suhete juht Riina Vändre, Riigikogu liige Mart Nutt, ajakirjanik Toomas Kümmel

  2. As endemias rurais na Folha SA.22 Belém, do projeto RADAM

    Directory of Open Access Journals (Sweden)

    Mario B. Aragão

    1987-12-01

    Full Text Available Utilizando dados sobre as endemias rurais ou seus vetores e os mapas geológico, geomorfológico e de vegetação, foi possível separar áreas onde essas endemias podem ou não ocorrer. A malária não ocorre num tipo de chapada e noutro de várzea. Só estará livre de leishmaniose muco-cutânea a floresta da placínie aluvial. Já a cutânea difusa é restrita a algumas matas de várzea. Os caramujos hospedeiros intermediários da esquitossomose poderão aparecer, depois do desmatamento, em todas as áreas não sujeitas a inundação. A febre amarela tem ocorrido em todas as florestas e até nas matas ciliares das zonas campestres.Using data from endemic diseases from rural areas and their vectors and geologic, geomorphological and vegetation maps it was possible to plot areas where these diseases are possible to occur. Malaria is not found in one type of plateau and in another type of floodplain. Only the floodplains are free of muco-cutaneous leishmaniasis and the diffuse cutaneous form is restricted to some floodplains forest. Snail intermediate host of schistosomiasis can appear, after deforestation, in all areas presently not periodically flooded. Yellow fever has been found in all forest types, including the gallery forest of grasland zones.

  3. Acute diarrhoea associated with Cryptosporidium sp in Belém, Brazil (preliminary report)

    OpenAIRE

    Loureiro, Edvaldo Carlos Brito; Linhares, Alexandre da Costa; Mata, Leonardo

    1986-01-01

    Cryptosporidium sp was detected in faeces from three children suffering from acute diarrhoea. In two cases no other concomitant agents were detected and in a 3rd. this agent was associated with Entamoeba histolytic, Entamoeba coli, Endolimax nana, Chilomastix mesnili and Pentatricbomonas hominis. Amostras de Cryptosporidium sp foram detectadas das fezes de três crianças com diarréia aguda. Em dois casos nenhum outro agente foi registrado, concomitantemente, e no terceiro caso, esse coccidi...

  4. Acute diarrhoea associated with Cryptosporidium sp in Belém, Brazil (preliminary report

    Directory of Open Access Journals (Sweden)

    Edvaldo Carlos Brito Loureiro

    1986-04-01

    Full Text Available Cryptosporidium sp was detected in faeces from three children suffering from acute diarrhoea. In two cases no other concomitant agents were detected and in a 3rd. this agent was associated with Entamoeba histolytic, Entamoeba coli, Endolimax nana, Chilomastix mesnili and Pentatricbomonas hominis.

  5. Political anomalies and web-based civil antibodies in Silvio Berlusconi’s Bel Paese

    Directory of Open Access Journals (Sweden)

    Giovanni Navarria

    2012-02-01

    Full Text Available Italy’s complex history has produced some remarkable path-breaking experiences and quite a few dangerous anomalies (such as Silvio Berlusconi’s media driven political regime,but it has also made the country the perfect ground for testing experimental antibodies that can contrast such anomalies. One of these antibodies is the web-based civil society orbitingaround the blog Beppegrillo.it. This article argues that the story of such community shows the path to follow for the Italian civil society. Grillo and his fellow bloggers in fact have so far demonstrated that new communication media have the potential to free citizens’ from control and at the same time increase their capacity to keep a close watch on power.La compleja historia de Italia presenta algunas experiencias innovadoras así como bastantes anomalías peligrosas (por ejemplo el régimen mediáticamente controlado de SilvioBerlusconi, pero ha convertido también el país en el territorio perfecto para el surgimiento de anticuerpos que pueden contrastar dichas anomalías. Uno de estos anticuerpos es la sociedad civil basada en la web que gira en torno al blog Beppegrillo.it. Este artículo argumenta que la historia de dicha comunidad muestra el camino a seguir para la sociedad civil italiana. Grillo y el conjunto de sus seguidores blogeros han demostrado de hecho que nuevos medios de comunicación tienen el potencial de liberar a los ciudadanos del control y a su vez aumentar su capacidad para mantener estrechamente vigilado al poder.

  6. Design av oppbevaringsprodukt: Utvikling av et entrémøbel for IKEA

    OpenAIRE

    Bosvik, Helene

    2010-01-01

    Et av IKEAs store satsingsområder er oppbevaring. IKEA ønsker å nå ut til så mange mennesker som mulig med sine produkter. Deres visjon om å skape en bedre hverdag for de mange menneskene er et bevis på dette. Temaet for dette masterprosjektet har vært oppbevaring. En del av oppgaven har også vært å finne fokusområde innenfor temaet oppbevaring. Valget falt på entreen og utviklingen av entrémøbelet RÅDE. Oppgaven er gjort i samarbeid med IKEA Leangen i Trondheim. RÅDE er utviklet blant an...

  7. Jesuits' Contribution to Meteorology.

    Science.gov (United States)

    Udías, Agustín

    1996-10-01

    Starting in the middle of the nineteenth century, as part of their scientific tradition, Jesuits founded a considerable number of meteorological observatories throughout the world. In many countries, Jesuits established and maintained the first meteorological stations during the period from 1860 to 1950. The Jesuits' most important contribution to atmospheric science was their pioneer work related to the study and forecast of tropical hurricanes. That research was carried out at observatories of Belén (Cuba), Manila (Philippines), and Zikawei (China). B. Viñes, M. Decheyrens, J. Aigué, and C.E. Deppermann stood out in this movement.

  8. Lugar de mulher é em casa?: cotidiano, espaço e tempo entre mulheres de famílias de pescadores

    OpenAIRE

    ANDERSON, Kirla Korina dos Santos

    2007-01-01

    Trata da compreensão da participação de homens e mulheres na manutenção doméstica de famílias de pescadores no Distrito de Icoaraci, município de Belém/PA. Para isso, observei, analisei e interpretei como organizam as atividades em casa e na pesca, partindo das expectativas que influenciam suas práticas cotidianas por gênero e dando atenção, especialmente, para os espaços freqüentados e organização do tempo pelas mulheres. Como procedimento metodológico, utilizei dados do Anuário ...

  9. Synthesis and cytotoxic evaluation of novel C-10 nitrate derivatives of colchicine

    International Nuclear Information System (INIS)

    Shen, L.H.; Wang, B.; Liu, S.M.

    2016-01-01

    In our continuing search for more potent anticancer agent, eight novel nitrates couple with C-10 colchicine nitric oxide-releasing derivatives (5a-f and 7a-b) were prepared. These target compounds were assayed for their anti-tumor activity in vitro against four cancer cell lines, including human hepatocellular carcinoma cells (BEL7402), human ovary carcinoma cells (A2780), human lung adenocarcinoma cells (A549) and human breast carcinoma cells (MCF7). Preliminary results indicated that most of them exhibited significant cytotoxic effect toward cancer cells. Compound 7a was investigated further for its more potent cytotoxicity than colchicine. (author)

  10. Propuesta de modelo de planeación estratégica para la empresa Multimodal Operador Logístico S. A.

    OpenAIRE

    Zamora Ureña, Luis Felipe

    2015-01-01

    Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Administración y Dirección de Empresas con énfasis en Gerencia, 2015 Multimodal Operador Logístico S.A. es una empresa de capital costarricense, con sede en el cantón de Belén de la provincia de Heredia, dedicada a proveer servicios logísticos a sus clientes, tales como: correduría aduanera, transporte internacional de carga, tanto de importación como de exportación bajo cualquie...

  11. Acanthocephala Larvae parasitizing Ameiva ameiva ameiva (Linnaeus, 1758) (Squamata: Teiidae).

    Science.gov (United States)

    Macedo, Lilian Cristina; Melo, Francisco Tiago de Vasconcelos; Ávila-Pires, Teresa Cristina Sauer; Giese, Elane Guerreiro; dos Santos, Jeannie Nascimento

    2016-01-01

    Knowledge concerning the taxonomy and biology of species of Acanthocephala, helminth parasites of the helminth species of the phylum Acanthocephala, parasites of lizards in Brazilian Amazonia, is still insufficient, but reports of Acanthocephala in reptiles are becoming increasingly common in the literature. Cystacanth-stage Acanthocephalan larvae have been found in the visceral peritoneum during necropsy of Ameiva ameiva ameivalizards from the "Osvaldo Rodrigues da Cunha" Herpetology Collection of the Emílio Goeldi Museum, Belém, Pará, Brazil. The aim of this study was to present the morphological study of the Acanthocephala larvae found in A. ameiva ameiva lizard.

  12. Acción

    OpenAIRE

    Aranegui, Mónica; Cámara, Chari; Atrapados en el Acto, (Colectivo); Gagaliot, Azahara; García Vázquez, Alejandro; González Longino, Teresa; Osset, Blanca; Ríos, Alexander; Sáez de Asteasu, Estibalez; Sumatorio de vacíos, (Colectivo); Valls, Pierre; Ortega, Cristina; Bocanegra, Juan José; Sánchez, Ana Rosa; Cueto, Belén

    2012-01-01

    Coordinación, Belén Cueto y Nieves Correa. Acción es el compendio de tres actividades relacionadas con el arte de acción que se realizaron dentro del programa SIN CRÉDITOS del Vicedecanato de Extensión Universitaria en La Trasera de la Facultad de Bellas Artes durante 2012: Atrapados en el Acto propone un viaje teórico-práctico por la historia de la performance, seguido de un entramado de ejercicios que exploraban cuatro pilares del arte de acción: tiempo, espacio, cuerpo e interacción. Al...

  13. Isolation, Characterization, and Bioactivity Evaluation of 3-((6-Methylpyrazin-2-ylmethyl-1H-indole, a New Alkaloid from a Deep-Sea-Derived Actinomycete Serinicoccus profundi sp. nov.

    Directory of Open Access Journals (Sweden)

    Yong-Hong Liu

    2012-12-01

    Full Text Available One new alkaloid, 3-((6-methylpyrazin-2-ylmethyl-1H-indole (1 was obtained from the deep-sea actinomycete Serinicoccus profundi sp. nov., along with five known compounds (2–6. Their structures were determined on the basis of detailed analysis of the 1D and 2D NMR as well as MS data. The new indole alkaloid displayed weak antimicrobial activity against Staphylococcus aureus ATCC 25923 with an MIC value of 96 μg/mL. It showed no cytotoxicity on a normal human liver cell line (BEL7402 and a human liver tumor cell line (HL-7702.

  14. Genre et jeunesse à l'époque contemporaine

    Directory of Open Access Journals (Sweden)

    Véronique Blanchard

    2009-08-01

    Full Text Available Adams Mary Louise. The Trouble with Normal: Postwar Youth and the Making of Heterosexuality. Toronto, University of Toronto Press, 1997, 256 p.Bantigny Ludivine, Le plus bel âge ? - Jeunes et jeunesse en France de l'aube des « Trente Glorieuses » à la guerre d'Algérie, Paris, Fayard, 2007, 498 p.Bard Christine, « Jeunesse de la garçonne », in Ludivine Bantigny, Ivan Jablonka (dir., Jeunesse oblige. Une histoire des jeunes en France (XIXe-XXIe siècles, Paris, PUF, 2009, pp. 111-126.Blanchard...

  15. SOLOS GERADOS A PARTIR DO INTEMPERISMO DE CROSTAS LATERÍTICAS SÍLICO-FERRUGINOSAS

    OpenAIRE

    HORBE, Adriana Maria Coimbra; COSTA, Marcondes Lima da

    1997-01-01

    A porção superior de dois perfis lateriticos localizados nos balneáreos de Outeiro e Mosqueiro, no município de Belém (Pará-Brasil), é constituída pela crosta sílico-ferruginosa e seus fragmentos de crosta, com material areno-argiloso sobreposto formando o solo. A estrutura colunar preservada, o grau de arredondamento crescente dos fragmentos e a composição mineralógica e química demonstram que há uma passagem gradacional entre a crosta, fragmentos e o solo dos dois perfis. Assim, é possível ...

  16. Escenario de la presencia italiana en La Plata : El edificio del Banco de la provincia de Buenos Aires como objeto de análisis

    OpenAIRE

    Carbonari, Fabiana Andrea; Grandis, María Belén de

    2015-01-01

    El presente artículo se inscribe en el plan de trabajo de la Beca Interna de Entrenamiento en Investigación de la FAU denominada Italianos en la ciudad de La Plata. El caso del Banco Provincia de la ciudad de La Plata que, durante el ciclo lectivo 2015 desarrolla la Arq. María Belén de Grandis con dirección de la Esp. Arq. Fabiana Carbonari. La misma tiene por objetivo realizar el estudio histórico sistemático del Banco de la Provincia de Buenos Aires. En ese sentido, propone analizar las tra...

  17. Permanecer en el tiempo: el caso del Banco Provincia Casa Matriz 1885-2015

    OpenAIRE

    Carbonari, Fabiana Andrea; Bonicatto, Virginia; Grandis, María Belén de

    2015-01-01

    El presente artículo se inscribe en el plan de trabajo de la Beca Interna de Entrenamiento en Investigación de la FAU denominada Italianos en la ciudad de La Plata. El caso del Banco Provincia de la ciudad de La Plata que, durante el ciclo lectivo 2015 desarrolla la Arq. María Belén de Grandis con dirección de la Esp. Arq. Fabiana Carbonari y Codirección de la Dra. Arq. Virginia Bonicatto. La misma tiene por objetivo realizar el estudio histórico sistemático del Banco de la Provincia de Bueno...

  18. William Butcher, Jules Verne inédit, les manuscrits déchiffrés

    OpenAIRE

    Merello, Ida

    2016-01-01

    Les textes de Jules Verne sont des palimpsestes. Ils le sont au sens figuré, nous le savions déjà. Mais ils le sont également au sens propre, comme le montre le bel ouvrage de William Butcher. Ce dernier s’est donné pour objectif d’analyser les manuscrits de Verne parvenus jusqu’à nous. La ressource semble inépuisable : des milliers et des milliers de pages autographes à déchiffrer, à défricher. William Butcher s’est plongé dans ce labeur avec enthousiasme et il en tire de nombreuses informat...

  19. "First" and "Third" World Feminism(s: Does Paul Ricoeur’s Philosophy Offer a Way to Bridge the Gap?

    Directory of Open Access Journals (Sweden)

    Stephanie Riley

    2013-06-01

    Full Text Available This essay considers how Paul Ricoeur’s philosophy, including his philosophical hermeneutics and narrative theory, could be employed to facilitate dialogue and understanding between feminists from different contexts. Authors such as bel hooks and Hélène Cixous frame feminist tenets of liberation from sexual oppression and validation of the body as a source of knowledge. Weaving together Ricoeur’s writing and theories with the work of two feminist scholars, Trinh T. Minh-ha and Grace M. Cho, illuminates the potential Ricoeur’s work has to play a part in feminist discourse. 

  20. Transferring knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Rotondo, A. [Bedeschi SpA (Italy)

    2003-10-01

    The paper illustrates how to overcome the problem recently posed to Bedeschi SpA by Holcim SA, the owner of the Ciment Alesd installation in Romania, of how to store coal and petcoke without mixing them. The solution involved a longitudinal ditch park 180 mm x 22 mm which included two STKP 22/800 stacking bridges, an NGMR 78/800 reversible conveyor belt for the deposit system, and a BEL C 20/20 reclaimer to recover the material. Bedeschi machines together with advanced electronic units have made it possible to satisfy the plant's needs. 2 figs., 1 photo.