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Sample records for behandling ved lokalavanceret

  1. Kirurgisk behandling ved lokalavanceret pancreascancer

    DEFF Research Database (Denmark)

    Fristrup, Claus Wilki; Pless, Torsten; Hovendal, Claus

    2009-01-01

    Treatment of patients with locally advanced pancreatic cancer remains a challenge, and the exact role of surgery with vascular resection remains unclear. Several studies on selected patient populations have addressed the problem, but with varying results. Although venous resection may be performe...

  2. Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Munch, Lene; Røder, Michael E; Hansen, Ida H

    2018-01-01

    Hovedbudskaber • Sundhedsstyrelsen lægger vægt på tværsektorielt samarbejde omkring patienten med type 2-diabetes, men denne tankegang er dog ikke implementeret i det danske sundhedsvæsen • På organisatorisk niveau kan en stratificerings- og forløbsmodel give anvisninger til opgave- og...... udnyttelse af sundhedsvæsenets ressourcer samtidig med, at behandling af høj kvalitet fastholdes og udvikles for patienter med type 2-diabetes...

  3. Behandling ved tidlig Hodgkin's sygdom

    DEFF Research Database (Denmark)

    Specht, L K; Carde, P; Mauch, P

    1993-01-01

    indicate that we still do not definitively know whether or not the early addition of prophylactic chemotherapy improves survival. Arguments in favour of early chemotherapy are: that laparotomy may be avoided, that radiation fields and doses may perhaps be reduced, and that the stress of experiencing...... a relapse is avoided in many patients. The major argument against early chemotherapy is: that by careful staging and selection of patients and by careful radiotherapy techniques the number of patients exposed to potentially toxic chemotherapy may be kept at a minimum. Recently, trials have been carried out...

  4. Behandling ved tidlig Hodgkin's sygdom

    DEFF Research Database (Denmark)

    Specht, L K; Carde, P; Mauch, P

    1993-01-01

    indicate that we still do not definitively know whether or not the early addition of prophylactic chemotherapy improves survival. Arguments in favour of early chemotherapy are: that laparotomy may be avoided, that radiation fields and doses may perhaps be reduced, and that the stress of experiencing...

  5. Receptindløst anti-osteoporotisk behandling i Danmark

    DEFF Research Database (Denmark)

    Hansen, Carrinna; Konradsen, Hanne; Pedersen, Birthe D.

    den farmaceutiske behandling er fortsat uklare. Formål: At opnå en dybere forståelse af patienters liv med osteoporose ved at bestemme omfanget af, samt beskrive faktorer vedrørende receptindløst compliance og vedholdenhed af oral anti-osteoporotisk behandling blandt nye brugere af oral anti......-osteoporotisk medicin i Danmark. Metode: En epidemiologisk registerbaseret national åben kohorte undersøgelse af compliance og vedholdenhed af anti-osteoporotisk behandling. Undersøgelsen omfattede 100.949 mænd og kvinder. Statistiske analyser blev anvendt til at forklare årsager til behandlingssvigt, herunder backward...... præparater, hormon behandling, prednisolon og anti-depressiva, ko-morbiditeter særligt 3 og derover, lunge og reumatologisk lidelser. Konklusion: Studiets fund bidrager med ny viden vedrørende compliance problematikken, ved at beskrive afgørende faktorer for potentielle risikogrupper. Resultaterne peger...

  6. Gruppebaseret behandling af BED - et faseopdelt behandlingstilbud

    DEFF Research Database (Denmark)

    Laust, Jakob; Lau, Marianne Engelbrecht; Waaddegaard, Mette

    2015-01-01

    konsekvenser. BED blev i 2013 optaget i DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) som en selvstændig diagnose og BED forventes medtaget i den forestående revision af det internationale diagnose system, ICD-11. Sundhedsstyrelsen gav på denne baggrund satspuljemidler til erfaringsopsamling...... EDE-Q: 1,7 og ved EDI: 1,5), ligesom de generelle psykiske symptomer blev mindsket i høj grad (effectsize ved WHO-5: 1,0 og ved GSI meanscore: 0,8). I alt 82 % opfyldte før behandlingens start DSM-4’s diagnostiske kriterier for BED mod 11,5 % efter behandling. 52 % fik fuld remission (ingen...... accept af og tilfredshed med behandlingen. Der var stor effekt på antal overspisninger. Før behandling havde patienterne gennemsnitligt 23,7 overspisninger pr. mdr. mod 2,3 efter behandling (effect size: 5,4). Udbyttet i forhold til den samlede spiseforstyrrelsessymptomatologi var høj (effect size ved...

  7. Skattemæssig behandling af virtuelle valutaer

    DEFF Research Database (Denmark)

    Kjærsgaard, Louise Fjord; Weber, Katja Dyppel

    2018-01-01

    Udbredelsen og anvendelsen af virtuelle valutaer er stigende, og der synes derfor behov for en analyse af den skattemæssige kvalifikation og behandling heraf. Skatterådet har ved to lejligheder haft mulighed for at foretage denne analyse; i henholdsvis SKM2014.226.SR om Bitcoins og SKM2017.520.SR...

  8. Behandlingsmuligheder ved xerostomi og hyposalivation

    DEFF Research Database (Denmark)

    Jensen, Siri Beier; Dynesen, Anja Weirsøe; Pedersen, Anne Marie Lynge

    2011-01-01

    Behandlingsmuligheder ved nedsat spytsekretion og xerostomi For at kunne iværksætte adækvat lindring og behandling af nedsat spytsekretion og xerostomi bør det tilstræbes, at den tilgrundliggende årsag i videst muligt omfang er forsøgt diagnosticeret. I en del tilfælde er det dog ikke muligt at u...... infektioner, særlig oral candidose. Hvis det drejer sig om lægemiddelinduceret xerostomi og nedsat spytsekretion, kan en effektiv, lindrende behandlingsstrategi være af stor betydning for at sikre overholdelse af lægemiddelindtagelsen....

  9. Diagnose, behandling og prognose ved fibromyalgi

    DEFF Research Database (Denmark)

    Danneskiold-Samsøe, Bente; Bartels, Else Marie; Amris, Kirstine

    2010-01-01

    It is important to recognize the diagnosis of fibromyalgia (FM) to adequately advise patients with this chronic pain disease. FM coexists with other rheumatic diseases and may therefore serve as a confounder in connection with estimation of disease activity. The aetiology and pathogenesis of FM...... remain unknown, although central sensitisation seems to play a major role. Following exclusion of a number of differential diagnoses, the remaining patients have several treatment options including centrally-acting medication....

  10. Akut kirurgisk behandling ved malignt cerebralt infarkt

    DEFF Research Database (Denmark)

    Lilja-cyron, Alexander; Eskesen, Vagn; Hansen, Klaus

    2016-01-01

    Malignant stroke is an intracranial herniation syndrome caused by cerebral oedema after a large hemispheric or cerebellar stroke. Malignant middle cerebral artery infarction is a devastating disease with a mortality around 80% despite intensive medical treatment. Decompressive craniectomy reduces...

  11. Akut kirurgisk behandling ved malignt cerebralt infarkt

    DEFF Research Database (Denmark)

    Lilja-Cyron, Alexander; Eskesen, Vagn; Hansen, Klaus

    2017-01-01

    Malignant stroke is an intracranial herniation syndrome caused by cerebral oedema after a large hemispheric or cerebellar stroke. Malignant middle cerebral artery infarction is a devastating disease with a mortality around 80% despite intensive medical treatment. Decompressive craniectomy reduces...

  12. Mentaliseringsbaseret behandling og musikterapi

    DEFF Research Database (Denmark)

    Hannibal, Niels

    2013-01-01

    Denne artikel behandler spørgsmålet, om mentaliseringsbaseret terapi er en metode der medfører et skift i terapeutisk forholdemåde for analytisk orienterede musikterapeuter i arbejde med patienter med personlighedsforstyrrelse. Artiklen skal ses om en del af den teoretiske integrationer af MBT i ...

  13. Behandling af epilepsi ved stimulation af nervus vagus

    DEFF Research Database (Denmark)

    Hansen, Christian Pilebaek; Sidenius, Per Christian; Gyllenborg, Jesper

    2010-01-01

    Epilepsy is a common neurological disorder, and between one fourth and one third of the patients do not obtain seizure freedom after treatment with antiepileptic drugs. If the epileptic seizures in such patients have severe consequences, the patients should be assessed for epilepsy surgery. In ca...

  14. Behandling af epilepsi ved stimulation af nervus vagus

    DEFF Research Database (Denmark)

    Hansen, Christian Pilebaek; Sidenius, Per Christian; Gyllenborg, Jesper

    2010-01-01

    epilepsy surgery is not feasible, vagus nerve stimulation (VNS) should be offered. VNS seems to have an effect in all epilepsy syndromes and seizure types. VNS is generally well-tolerated, and may even improve mood and quality of life. Many more epilepsy patients in Denmark should be offered VNS....

  15. Bedre prognose af cystinose ved behandling med cysteamin og nyretransplantation

    DEFF Research Database (Denmark)

    Oczachowska-Kulik, Anna Ewa; Lund, Allan; Skovby, Flemming

    2011-01-01

    Cystinosis is a rare, autosomal recessive disease with cystine deposits in different tissues. First signs come from kidneys and eyes, but during progression of the disease other organs can also be affected. Previously, patients with cystinosis had a very poor prognosis, but it is now considerably...

  16. Forebyggende ambulant behandling ved affektiv lidelse (depression og mani)

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Hansen, Hanne Vibe; Hougaard, Esben

    2007-01-01

    The present article is based on a Health Technology Assessment Report (HTA, available with an English summary at www.cemtv.dk) on preventive out-patient treatment of affective disorders. The article briefly reviews the course of depressive disorder and bipolar affective disorder and reviews...... the best available treatment modalities including shared care models, prophylactic pharmacotherapy and prophylactic combination therapy involving pharmacotherapy and psychological treatment....

  17. Behandling af epilepsi ved stimulation af nervus vagus

    DEFF Research Database (Denmark)

    Hansen, Christian Pilebaek; Sidenius, Per Christian; Gyllenborg, Jesper

    2010-01-01

    Epilepsy is a common neurological disorder, and between one fourth and one third of the patients do not obtain seizure freedom after treatment with antiepileptic drugs. If the epileptic seizures in such patients have severe consequences, the patients should be assessed for epilepsy surgery. In case...

  18. Nyrepåvirkning ved behandling af hjertesvigt

    DEFF Research Database (Denmark)

    Rasmussen, Zhiying Zhang; Barfod, Toke; Klit, Jakob

    2009-01-01

    The case of a 66-year-old male with heart failure and cardiorenal syndrome is presented. The patient had normal renal function before intensive treatment with diuretics and ACE inhibitor. Shortly after the ACE inhibitor was stopped and diuretics were either stopped or reduced in dosage, his renal...

  19. Forekomst og behandling af seksuel dysfunktion ved hjertesygdom

    DEFF Research Database (Denmark)

    Mickley, Hans

    2002-01-01

    Several links have been established between sexual dysfunction and heart disease. Indeed, many risk factors for developing sexual dysfunction are shared by coronary artery disease: age, smoking, diabetes, hypertension, and hypercholesterolaemia. It should also be borne in mind that in men several...... cardiac drugs are responsible for erectile dysfunction (ED). Lastly it should be remembered that treatment of ED may be associated with cardiovascular side-effects. Data from the literature show that men with coronary artery disease, hypertension or diabetes have an up to fourfold higher risk...

  20. Antitrombotisk behandling ved iskaemisk apopleksi og transitorisk cerebral iskaemi

    DEFF Research Database (Denmark)

    Overgaard, Karsten; Poulsen, Tina Svenstrup; Husted, Steen E

    2007-01-01

    In acute ischemic stroke and transient ischemic attack (TIA), aspirin is recommended to all patients (except immediately following thrombolysis). Heparin and anticoagulant therapy using vitamin K antagonists should be avoided in the acute phase. Secondary preventive antithrombotic treatment...... includes anticoagulation in patients with cardioembolic stroke and antiplatelet agents aspirin possibly combined with dipyridamole or clopidogrel alone in patients with non-cardioembolic stroke. Other individual risks may modify this treatment regimen. Udgivelsesdato: 2007-Oct-1...

  1. Omkostningseffektivitet ved behandling af type 1-diabetes med insulinpumpe

    DEFF Research Database (Denmark)

    Nørgaard, Kirsten; Sohlberg, Anna; Goodall, Gordan

    2010-01-01

    This study's aim was to project the long-term clinical and economic outcomes of continuous subcutaneous insulin infusion (CSII) treatment compared to multiple daily injections (MDI) in type 1 diabetes patients in Denmark.......This study's aim was to project the long-term clinical and economic outcomes of continuous subcutaneous insulin infusion (CSII) treatment compared to multiple daily injections (MDI) in type 1 diabetes patients in Denmark....

  2. Bivirkninger ved N-acetylcystein-behandling af paracetamolforgiftede patienter

    DEFF Research Database (Denmark)

    Schmidt, L E; Dalhoff, K P

    1999-01-01

    number of patients will be treated with NAC than with previous regimens based on plasma concentrations of paracetamol. In this retrospective study we evaluated the incidence of side effects of NAC in 310 patients admitted to the Department of Hepatology, Rigshospitalet, Copenhagen, over a four-year...... period (1.1.1994-31.12.1997). Twenty-six (8.4%) patients developed side effects. Side effects were anaphylactoid, mainly from skin (25 rash, pruritus or flushing), in rare cases more serious (four bronchospasm, three angioedema, one hypotension). None were life-threatening and all patients received...

  3. Behandling af elmesyge

    DEFF Research Database (Denmark)

    Thomsen, Iben Margrete; Kristoffersen, Palle

    2004-01-01

    Ingen midler er p.t. godkendt og dermed lovlige til bekæmpelse af elmesyge i Danmark. Lovprisning af nye behandlinger ses f.eks. på internettet, men dokumentation mangler. Økonomien og nytten ved en kemisk bekæmpelse frem for sanering af syge træer skal afvejes nøje....

  4. Mentaliseringsbaseret behandling og musikterapi

    Directory of Open Access Journals (Sweden)

    Niels Hannibal

    2013-06-01

    Full Text Available Denne artikel behandler spørgsmålet, om mentaliseringsbaseret terapi er en metode der medfører et skift i terapeutisk forholdemåde for analytisk orienterede musikterapeuter i arbejde med patienter med personlighedsforstyrrelse. Artiklen skal ses om en del af den teoretiske integrationer af MBT i musikterapi med denne målgruppe. Artiklen ser på de forskrifter til mentaliseringsfremmende tiltag som Allan, Fonagy og Bateman (2010 beskriver. Artiklens konklusion er dels af MBT’s krav til forholdemåde og interventionsfokus er et skift i forhold til traditionel analytisk orienteret terapi, bl.a. i forhold til fokus på her og nu, og øget fokus på implicit relationel læring, men siger samtidig at musikterapi allerede lever op til og i forvejen anvender disse elementer i musikterapi qua ligheden mellem klinisk improvisation (Wigram 2004 og implicit relationel viden (Stern 2010.

  5. Gentaget selvmordsforebyggende behandling

    DEFF Research Database (Denmark)

    Lind, Bertel

    2014-01-01

    ramme er casestudie (Yin 2009; George 2005; Flyvbjerg 1991). Casestudiet består af en række patientforløb, hvor hver patient har haft mere end ét registreret behandlingsforløb i databasen (n = 377). Kvantitativ undersøgelse blev udført ved hjælp af Microsoft SPSS 21 på de 377 patienter på baggrund af...

  6. Evaluering av medisinsk behandling: Hva vet vi, og hvordan bør kunnskapen håndteres?

    Directory of Open Access Journals (Sweden)

    Jan Magnus Bjordal

    2009-09-01

    Full Text Available Kunnskap om effekten av medisinsk behandling fremskaffes i kliniske studier. Godt planlagte og gjennomførte randomiserte, placebokontrollerte studier tillegges størst vekt når data skal vurderes. De datamengdene vi besitter når det gjelder forskjellige behandlinger kan oppsummeres i oversikter eller terapianbefalinger som ofte blir normative for klinisk praksis. Dette stiller store krav til evalueringsprosedyrene. I denne oversiktsartikkelen diskuteres i innledningen noen eksempler på at kunnskapsgrunnlaget er blitt feiltolket. Deretter omtales kvalitetskriterier som legges til grunn i vurderingen av data, og den metodologiske basis for meta-analyser. Usikkerhetsmomenter og potensielle fallgruver ved bruk av meta-analyser omtales. Meta-analysens fortrinn eksemplifiseres ved bruk av data om behandling av korsryggsmerter, hvor det nylig er utarbeidet kliniske retningslinjer som etter vår oppfatning er beheftet med feil eller mangler. Meta-analysen har vesentlige fortrinn fremfor mindre formaliserte metoder for oppsummering av kunnskap om terapi ved sykdom

  7. Computertomografi anvendt ved retsmedicinske obduktioner

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Christoffersen, Søren

    2008-01-01

    Introduktion: Billeddiagnostiske metoder er ved at vinde indpas ved retsmedicinske obduktioner. Her redegøres for vores erfaringer med computertomografi (CT) ved retslægelige dødsfald. Materiale og metoder: Retrospektiv dobbeltblindet undersøgelse af 150 afdøde mennesker som blev CT-scannet og ob...

  8. Pressestivhed ved Verikal Belansning

    DEFF Research Database (Denmark)

    Paludan-Withen, Carsten; Marstrand, Jonas

    Dette projekt er udarbejdet som et polyteknisk midtvejsprojekt på Institut for Produktion og Ledelse. Det indgår som en del af EU-projektet Impress [1.], der drejer sig om at bestemme produktionspressers udbøjning under forskellige belastninger. Grundlaget for dette er, at man ved at kende en...

  9. Etiske betragtninger ved supervision

    DEFF Research Database (Denmark)

    Jacobsen, Claus Haugaard; Agerskov, Kirsten

    2007-01-01

    Kapitlet præsenterer nogle etiske betragtninger ved supervision. Mens der længe har eksisteret etiske retningslinjer for psykoterapeutisk arbejde, har der overraskende nok manglet tilsvarende vejledninger på supervisionsområdet. Det betyder imidlertid ikke, at de ikke er relevante. I kapitlet gøres...

  10. Ideudvikling ved kreativ innovation

    DEFF Research Database (Denmark)

    Sejer Jakobsen, Henning; Rebsdorf, S.O.

    og brugbar forståelse af hele skabelsesprocessen. Idestigen med Tanke - Ide - Løsning er hele grundlaget, og med introduktionen til Creative Idea Solution (CIS) gives læseren en konkret model for, hvordan en proces på grænsen af kaos kan blive til en kontrolleret forandringsproces. Det normative......Med begrebsdefinitioner og en solid videnskabsteoretisk fundering viser "Ideudvikling ved kreativ innovation" både hvorfor kreativitet og innovation er vigtigt, men også hvordan systematisk ideudvikling er muligt. Begreberne perspektiveres ved en historisk og normativ anskuelse, der giver en bred...... udgangspunkt er garant for at bogen aldrig bliver uvedkommende eller kan afskrives som endnu en publikation med overforbrug af buzzwords. Bogen efterlader læseren med en følelse af lige at være vågnet, og det nyopdagede potentiale skal nu udnyttes systematisk....

  11. Bivirkninger ved brintpiller

    DEFF Research Database (Denmark)

    Sørensen, Rasmus Zink; Klerke, Asbjørn; Christensen, Claus H.

    2008-01-01

    Hvad nu? Indrømmer forskerne fra DTU nu selv, at der er bivirkninger ved de brintpiller, som er blevet så berømte? Svaret er Ja. Faktisk er der en væsentlig bivirkning, som på kort sigt kan få større betydning, end brintpillernes evner til at lagre brint. Det forholder sig nemlig så heldigt, at b...

  12. Omkommet ved Brand

    DEFF Research Database (Denmark)

    Leth, Peter Mygind

      Afhandlingen består af tre delundersøgelser. Den første undersøgelse er en hypotesegenererende case-only undersøgelse af branddødsfald i hele landet i 1953-57 og 1988-92. I de to perioder omkom henholdsvis136 og 362 personer ved brandulykker. Mange af de omkomne var alkoholpåvirkede eller...

  13. Halsgreb ved kampsport

    DEFF Research Database (Denmark)

    Leth, Peter Mygind

    2015-01-01

    ”, hvor en person lægger armen rundt om halsen bagfra og presser underarmen vinkelret ind mod halsens forside. ”Carotid sleeper” har sit navn, fordi det medfører bevidstløshed, som indtræder indenfor 10 sekunder. Bevidstheden gen-vindes indenfor 10-20 sekunder. Halspulsårerne kan aflukkes ved et tryk på...

  14. Bør leger ha reservasjonsrett ved assistert befruktning?

    Directory of Open Access Journals (Sweden)

    Morten Magelssen

    2011-10-01

    Full Text Available Omfanget av helsepersonells reservasjonsrett har nylig vært gjenstand for debatt i Norge. Vi spør om leger bør ha reservasjonsrett ved utførelse og henvisning til assistert befruktning, og drøfter argumenter for og imot ved hjelp av et rammeverk med sju kriterier for vurdering av reservasjon. Reservasjonsrettens grunnleggende dilemma er hvordan to viktige hensyn, henholdsvis pasientens rett til behandling og hensynet til helsepersonellets moralske integritet, best kan ivaretas. Det argumenteres for at leger bør ha rett til å reservere seg mot å utføre, assistere ved og henvise til assistert befruktning generelt hvis begrunnelsen er hensynet til befruktede eggs moralske verdi. Videre finner vi at leger også kan ha en moralsk rett til reservasjon mot å utføre, assistere ved og henvise til assistert befruktning for likekjønnede, men da på nærmere spesifiserte vilkår.Nøkkelord: reservasjonsrett, assistert befruktning, samvittighet, moralsk integritetEnglish summary: Should physicians have the right to conscientiously object to assisted reproduction?The extent of the healthcare worker's right to conscientious objection has recently been debated in Norway. This article asks whether physicians should have a right to conscientious objection to the performance of, and referral for, assisted reproduction, and discusses arguments for and against the same, utilizing a framework of seven criteria for the evaluation of conscientious objection. The fundamental dilemma of conscientious objection is how two important considerations can be reconciled: the patient's right to treatment, and the protection of the healthcare worker's moral integrity. It is argued that physicians should have the right to object to performing, assisting with, and referring for assisted reproduction generally when the objection is grounded in the moral value of the embryo. Furthermore, physicians may also have a moral right to object to performing, assisting with, and

  15. Teknologiers mellemkomst i ambulant behandling og egenomsorg

    DEFF Research Database (Denmark)

    Ballegaard, Stinne Aaløkke; Aarhus, Rikke

    2009-01-01

    Vigtige tendenser i den danske sundhedssektor i disse år er centralisering af behandling og øget egenomsorg. Teknologi ses ofte som en del af denne udvikling, omend der eksisterer både dystopiske og utopiske forestillinger om, hvorvidt teknologi fremmedgør eller støtter patienten. I denne artikel...

  16. Manglende evidens for skadelig effekt på knogleheling ved behandling med NSAID

    DEFF Research Database (Denmark)

    Janum, Susanne; Kristensen, Billy Bjarne

    2012-01-01

    The use of NSAIDs for postoperative pain management following orthopaedic surgery or during conservative treatment of fractures is controversial. Experimental animal models suggest NSAIDs inhibit bone healing. In a review of the literature, there was no clinical evidence to support categorical...... discard of NSAID for postoperative pain relief in uncomplicated cases. However, NSAID should be considered a potentiel risk factor of impaired bone healing and avoided in patients with a high risk of pseudoarthrosis. Recommended daily doses should be respected and duration of treatment should be limited....

  17. Irreversibel nyreinsufficiens under behandling med angiotensin I konverterende enzymhaemmer ved bilateral nyrearteriestenose

    DEFF Research Database (Denmark)

    Kamper, A L

    1989-01-01

    A case of irreversible renal failure during treatment with enalapril in bilateral renal artery stenosis is described. In the use of converting enzyme inhibitors, caution and monitoring of renal function during treatment is advised....

  18. Ultralydskanning ved diagnostik og behandling af hoftedysplasi. Vurdering af en selektiv screeningsprocedure

    DEFF Research Database (Denmark)

    Strandberg, C.; Konradsen, L.A.; Ellitsgaard, N.

    2008-01-01

    INTRODUCTION: With the intention of reducing the treatment frequency of Developmental Dysplasia of the Hip (DDH), two hospitals in Copenhagen implemented a screening and treatment procedure based on selective referral to ultrasonography of the hip (US). This paper describes and evaluates...... 0.03%. No relationship was seen between morphological parameters at the first US and the outcome of hips classified as minor dysplastic or not fully developed (NFD). A statistically significant relationship was seen between the degree of dysplasia and the time until US normalization of the hips (p......= 0.02). There was no relapse of dysplasia after treatment. The median duration of treatment was six, eight and nine weeks for mild, moderate and severe dysplasia respectively. CONCLUSION: The procedure resulted in a low rate of treatment and a small number of late diagnosed cases. Prediction...

  19. Ultralydskanning ved diagnostik og behandling af hoftedysplasi. Vurdering af en selektiv screeningsprocedure

    DEFF Research Database (Denmark)

    Strandberg, Charlotte; Konradsen, Lars Aage Glud; Ellitsgaard, Niels

    2008-01-01

    With the intention of reducing the treatment frequency of Developmental Dysplasia of the Hip (DDH), two hospitals in Copenhagen implemented a screening and treatment procedure based on selective referral to ultrasonography of the hip (US). This paper describes and evaluates the procedure....

  20. Ultralydskanning ved diagnostik og behandling af hoftedysplasi. Vurdering af en selektiv screeningsprocedure

    DEFF Research Database (Denmark)

    Strandberg, C.; Konradsen, L.A.; Ellitsgaard, N.

    2008-01-01

    the procedure. MATERIALS AND METHODS: The procedure defines procedures for referral, diagnosis, treatment and follow-up of DDH. From 1998 to 2003 children with risk factors or with positive Ortolanis or Barlows test were referred to US. RESULTS: The treatment rate was 0.47%, and the rate of late diagnosed cases...

  1. Omkostningseffektiv ændring af behandling ved delhudstransplantat på crus

    DEFF Research Database (Denmark)

    Vennegaard Kalialis, Louise; von Sperling, Marie Louise; Hoyer, A.P.

    2012-01-01

    We present a clinical comparison of short stretch bandage versus a two-layer compression bandage and early mobilization after split skin grafting to lower leg defects. A total of 38 patients were included. The first group were immobilized for four days and given a short stretch support bandage. G...

  2. Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer

    DEFF Research Database (Denmark)

    Klein, M.; Gögenür, Ismayil; Rosenberg, J.

    2010-01-01

    strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis...

  3. Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler

    DEFF Research Database (Denmark)

    Schmidt, Morten; Fosbøl, Emil Loldrup; Torp-Pedersen, Christian

    2016-01-01

    cyclooxygenase-2 inhibitors has been associated with a substantial vascular risk but increasing concern also relates to traditional NSAIDs, in particular diclofenac. This review summarizes the current evidence regarding the cardiovascular safety of NSAIDs and presents recommendations for their use....

  4. Terapeutiske vacciner er et nyt behandlings-princip ved kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Djurhuus, Sissal Sigmundsdòttir; Brasso, Klaus; Berg, Kasper Drimer

    2015-01-01

    Therapeutic vaccines is a novel approach in castration-resistant prostate cancer treatment Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemo­therapy and novel...... endocrine agents have been approved for CRPC treatment. The continued need for new effective drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2...... and 3 trials of CRPC vaccines and discusses the impact on future CRPC management....

  5. Betydningen af kroppens stilling for det diuretiske respons ved behandling af dekompenseret cirrose og morbus cordis

    DEFF Research Database (Denmark)

    Wilken-Jensen, C; Ring-Larsen, H; Henriksen, Jens Henrik Sahl

    1989-01-01

    The diuretic effect of the supine position was evaluated in six patients with cirrhosis and ascites and six with congestive cardiac failure. All patients received 1 mg bumethanide intravenously and were randomly assigned to either bed rest in the supine position or normal daily activity in the up...

  6. Lægers tavshedspligt ved behandling af unge kan være et dilemma

    DEFF Research Database (Denmark)

    Adolphsen, Caroline; Boisen, Kirsten; Svensson, Jannet

    2016-01-01

    Confidentiality is paramount in healthcare, yet according to Danish guidelines, health professionals have to inform parents about their child´s situation until the age of 18 years. This is in contrast to Danish legislation regarding informed consent, where adolescents aged 15 years can consent to...

  7. Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer

    DEFF Research Database (Denmark)

    Klein, M.; Gögenür, Ismayil; Rosenberg, J.

    2010-01-01

    Anastomotic leakage is the most serious complication following colorectal resection. Recently, focus has been on possible effects of non-steroidal anti-inflammatory drugs (NSAIDs). Animal studies have found a correlation between treatment with NSAIDs and increased leakage rate, impaired anastomotic...... strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis...

  8. Blødningskomplikationer ved behandling med clopidogrel og acetylsalicylsyre efter akut koronart syndrom

    DEFF Research Database (Denmark)

    Kjær, Janus; Larsen, Christian Hastrup; Poulsen, Tina Svenstrup

    2006-01-01

    INTRODUCTION: The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study showed that patients with unstable angina pectoris (UAP) and non-ST-elevation myocardial infarction (NSTEMI) benefit from combined therapy with acetylsalicylic acid (ASA) and clopidogrel. However, only...... patients entering clinical randomized trials were studied. We sought to assess whether the risk of bleeding increased after the introduction of the CURE criteria in an unselected population of Danish patients with NSTEMI or UAP. MATERIALS AND METHODS: The CURE criteria were implemented in the Department...

  9. Omkostningseffektiv ændring af behandling ved delhudstransplantat på crus

    DEFF Research Database (Denmark)

    Vennegaard Kalialis, Louise; von Sperling, Marie Louise; Høyer, Anette Pernille

    2012-01-01

    We present a clinical comparison of short stretch bandage versus a two-layer compression bandage and early mobilization after split skin grafting to lower leg defects. A total of 38 patients were included. The first group were immobilized for four days and given a short stretch support bandage...

  10. Ventetid og omkostninger ved diagnostik og behandling af stabil angina pectoris

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Sanchez, Ricardo

    Introduction: The objective of this pilot study was to examine possible consequences of a logistically non-optimal regimen, for the diagnosis and treatment of stable angina pectoris, on waiting time and costs to inform whether a larger study is warranted. Material and methods: Retrospective cohort...... study among 104 consecutive patients referred on suspected stable angina pectoris. Data on the diagnostic regimen was systematically collected from patient files and data on other resource use was collected using a questionnaire for self- reporting. Non-parametric bootstrapping was applied. Results...... of stable angina pectoris, which ceteris paribus would be associated with cost savings in the health care sector. However, these potentials should be examined in a larger- scale study....

  11. Omkostningseffektiv ændring af behandling ved delhudstransplantat på crus

    DEFF Research Database (Denmark)

    Vennegaard Kalialis, Louise; von Sperling, Marie Louise; Hoyer, A.P.

    2012-01-01

    We present a clinical comparison of short stretch bandage versus a two-layer compression bandage and early mobilization after split skin grafting to lower leg defects. A total of 38 patients were included. The first group were immobilized for four days and given a short stretch support bandage....... Group 2 were mobilized one day after the operation with a two-layer compression bandage (Pro-Guide). There was no difference in healing or frequency of complications. The patients treated with Pro-Guide had significantly fewer admission days and out-patient consultations. Larger randomized trials...

  12. Manglende evidens for skadelig effekt på knogleheling ved behandling med NSAID

    DEFF Research Database (Denmark)

    Janum, Susanne; Kristensen, Billy Bjarne

    2012-01-01

    discard of NSAID for postoperative pain relief in uncomplicated cases. However, NSAID should be considered a potentiel risk factor of impaired bone healing and avoided in patients with a high risk of pseudoarthrosis. Recommended daily doses should be respected and duration of treatment should be limited....

  13. Tidlig identifikation og behandling af kredsløbssvigt ved svær sepsis

    DEFF Research Database (Denmark)

    Haase, Nicolai; White, Jonathan; Perner, Anders

    2010-01-01

    Severe sepsis is a leading cause of death characterised by infection-induced endothelial and cardiac dysfunction leading to hypovolaemia, maldistribution of flow, tissue ischaemia and organ failure. A clinical approach with focus on cardiovascular diagnostics and rational goal-directed therapy...

  14. Fra mental retardering til målrettet behandling ved fragilt X-syndrom

    DEFF Research Database (Denmark)

    Jønch, Aia Elise; Timshel, Susanne; Carlsen Lunding, Jytte Merete

    2014-01-01

    From intellectual disability to new treatment modalities of fragile X syndrome: Ugeskr Læger 2014;176:V06130350 In 1943 a large family with X-linked mental retardation was described by Martin & Bell. This family had what we know today as fragile X syndrome, the most common inherited form...... of intellectual disability. Current knowledge about the specific gene, the encoded protein and the pathophysiological mechanisms involved has made it possible to develop pharmacological treatment trials. Fragile X syndrome therefore is on its way as model disorder for targeted treatments in genetic medicine...

  15. Fra mental retardering til målrettet behandling ved fragilt X-syndrom

    DEFF Research Database (Denmark)

    Jønch, Aia Elise; Timshel, Susanne; Lunding, Jytte

    2014-01-01

    In 1943 a large family with X-linked mental retardation was described by Martin & Bell. This family had what we know today as fragile X syndrome, the most common inherited form of intellectual disability. Current knowledge about the specific gene, the encoded protein and the pathophysiological...... mechanisms involved has made it possible to develop pharmacological treatment trials. Fragile X syndrome therefore is on its way as model disorder for targeted treatments in genetic medicine, and this article reviews clinical and therapeutic aspects of the syndrome....

  16. Farmakologisk behandling af præmatur ejakulation

    DEFF Research Database (Denmark)

    Kuhlmann, Ida Berglund; Hedegaard, Ulla; Christensen, Mette Marie H

    2017-01-01

    Forfatterne anbefaler lokalanæstesi med lidokain og/eller prilokain som førstevalg. Andet valg til behandling vil være dapoxetin, som er en korttidsvirkende SSRI med indikationen præmatur ejakulation. Som tredje valg kan overvejes SSRI'et sertralin......Forfatterne anbefaler lokalanæstesi med lidokain og/eller prilokain som førstevalg. Andet valg til behandling vil være dapoxetin, som er en korttidsvirkende SSRI med indikationen præmatur ejakulation. Som tredje valg kan overvejes SSRI'et sertralin...

  17. Eksperimentel bakteriofagterapi til behandling af kronisk Pseudomonas aeruginosaotitis hos hund

    DEFF Research Database (Denmark)

    Moodley, Arshnee; Mølgaard, Jesper

    2016-01-01

    Vi beskriver en case med anvendelsen af bakteriofager til behandling af kronisk otitis forårsaget af multiresistente Pseudomonas aeruginosa som en sidste behandlingsmulighed før aflivning. Trods gentagne behandlinger, både topikalt og systemisk, med op til seks forskellige antibiotika over en...

  18. Psykomotorisk behandling og wellness til personer med demens

    DEFF Research Database (Denmark)

    Stamp, Anne Schinkel; Frausing, Kristian Park

    Rapporten evaluerer projektet Psykomotorisk behandling af personer med demens gennem fokusgruppeinterviews med deltagende studerende og personale fra deltagende centre. Samlet peges der på gavnligt udbytte for de demente beboere samt både personligt og fagligt udbytte for de deltagende studerende...

  19. Behandling af digital dermatitis på KFC

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    På Kvægbrugets Forsøgscenter blev de rutinemæssige klovbade i maj 2007 erstattet med månedlige tjek af klove i beskærerboks og behandling af klovlidelser, herunder især Digital Dermatitis. Behandlingseffekten har været høj med 90 % helbredte efter en måned. Udgivelsesdato: april 2008...

  20. Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

    DEFF Research Database (Denmark)

    Olesen, Anne Estrup; Jarvig, Line; Hansen, Ole Bo

    2007-01-01

    . For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment......30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids. Breakthrough pain can be treated with shorter acting non-opioid analgesics or opioids. The aim of this study...... was to describe the medical treatment of pain in cancer patients in connection with six Danish hospital units with special expertise in pain treatment. Differences in the prescription of analgesics were studied. The study was performed as a cross section study of prescribed analgesics. Data was collected...

  1. Behandling med duodenal-jejunal bypass-sleeve ved svær overvægt

    DEFF Research Database (Denmark)

    Rohde, Ulrich; Gylvin, Silas; Vilmann, Peter

    2014-01-01

    Overweight and obesity are risk factors for several co-morbidities reducing life expectancy. Conservative treatment of obesity is generally ineffective in the long-term. Bariatric surgery has proven effective, but is associated with potential complications. Duodenal-jejunal bypass sleeve is a novel...

  2. Præhospital behandling ved større udendørs musikfestival. Økonomiske aspekter

    DEFF Research Database (Denmark)

    Mikkelsen, J B; Larsen, C F

    1994-01-01

    An emergency facility was provided at the Midtfyn Rock Music Festival in 1990 (comprising 7,000 musicians and ancillaries and an overall public attendance of 60,000). A total of 329 patients were treated at the facility during the four and a half days that the festival lasted. The numbers of dise...... to the community was estimated to be about 25,000 DKR. Thus, the provision of an emergency facility was cost-effective, and is recommended at such mass outdoor gatherings as cultural and sports events....

  3. ACE-inhibitorer er fortsat førstevalg ved behandling af hjertesvigt--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Gadsbøll, Niels; Torp-Pedersen, Christian Tobias

    2013-01-01

    A new Cochrane metaanalysis has reviewed the literature on the use of angiotensin receptor blockers (ARB) in patients with heart failure and left ventricular systolic dysfunction. The conclusion supports the present recommendation from the European Society of Cardiology that angiotensin converting...... enzyme inhibitors (ACE-I) are first choice and that ARBs should be reserved to patients who are intolerant to ACE-Is. Neither ACE-Is nor ARBs are effective in the treatment of heart failure patients with normal left ventricular function....

  4. Hvad er fantastisk ved HBO-serien Game of Thrones?

    DEFF Research Database (Denmark)

    Schubart, Rikke

    2013-01-01

    Blogindlæg på videnskab.dk, kaldt "Hvad er fantastisk ved HBO-serien Game of Thrones?" om HBO tv-serien Game of Thrones......Blogindlæg på videnskab.dk, kaldt "Hvad er fantastisk ved HBO-serien Game of Thrones?" om HBO tv-serien Game of Thrones...

  5. Medarbejdernes retsstilling ved grænseoverskridende overtagelse og fusion

    DEFF Research Database (Denmark)

    Hansen, Lone L.

    Bogen, der er en publiceret ph.d.-afhandling, analyserer en række komplekse spørgsmål om medarbejdernes retsstilling, når den virksomhed, de arbejder i, overtages af en udenlandsk virksomhed gennem majoritetsovertagelse, virksomhedsoverdragelse, fusion eller spaltning. Afhandlingen behandler over...

  6. Behandling af patienter med Guillan Barré syndrom

    DEFF Research Database (Denmark)

    Oliel, Vibeke S.

    2011-01-01

    Resumè Guillain Barrés syndrom er en autoimmum sygdom karakteriseret ved motorisk, sensorisk og autonom dysfunktion. I Danmark rammes omkring 80 personer i alle aldre årligt af sygdommen. Akut inflammatorisk polyradikoloneuropati rammer de perifere nervers nerveskeder og medfører progredierende...

  7. Helbredsrelateret livskvalitet ved kræft

    DEFF Research Database (Denmark)

    Grønvold, Mogens

    2008-01-01

    I denne artikel gennemgås metoder, erfaringer og resultater fra livskvalitetsforskningen på kræftområdet, og der opstilles anbefalinger. Forskningen har omfattet deskriptive undersøgelser, endemål i kliniske undersøgelser, prognostiske studier og klinisk anvendelse af livskvalitetsskemaer. Der vu...... vurderes at være behov for yderligere livskvalitetsundersøgelser ved alle kræftformer og -behandlinger, men de bør kun foretages, når de tilstrækkelige resurser er til stede, da kun velgennemførte studier er af værdi. Udgivelsesdato: 2008-Mar-3...

  8. Epidemiologi ved systemisk lupus erythematosus (SLE

    Directory of Open Access Journals (Sweden)

    Inge-Margrethe Gilboe

    2009-10-01

    Full Text Available Det er utført få epidemiologiske studier av SLE i Norge. De studier som er utført viser liknende hyppighet og forekomst av SLE i Norge som i de øvrige nordiske land og forekomst av mild sykdom med en lav andel av alvorlig indre organ manifestasjoner. Insidens og prevalens er kartlagt i Nord-Norge visende en lavere insidens enn i de øvrige nordiske land, mens prevalensen er sammenliknbar. Tall fra Sverige tyder på stabil insidens, men økende prevalens, forenelig med økt overlevelse. Norske og nordiske studier viser høy kvinneandel og sammenliknbar alder ved diagnose. Studiene tyder på en høyere alder ved diagnose i Skandinavia enn i USA og England. Ut fra de nordiske studier er overlevelsen ved SLE god, selv om den er lavere enn i den generelle befolkningen. Overlevelse i de nordiske og europeiske land er sammenliknbare.Selv om overlevelsen ved SLE er betydelig bedret over tid utgjorde aktiv SLE og infeksjoner 50% av dødsårsakene i den danske mortalitetsstudien. Aterosklerotisk hjerte-karsykdom var en hyppig dødsårsak i alle studiene. Kardiovaskulær sykdom som hovedårsak til død ved SLE er påvist i den store internasjonale studien hvor pasienter fra Island og Sverige deltok og i andre europeiske og internasjonale studier. Betydelig økt risiko for hjerteinfarkt hos unge SLE-kvinner i Sverige er også påvist tidligere i internasjonale studier og styrker teorien om at SLE per ce er en selvstendig risikofaktor for aterosklerose. Det er ønskelig med flere epidemiologiske studier av SLE i Norge.There has been few studies on the epidemiology of SLE in Norway. The studies that have been conducted show similar frequency and occurence of SLE in Norway in comparison to the other Nordic countries, and mainly occurence of mild disease with only a low proportion suffering severe internal organ involvement. Studies on incidence and prevalence in the northern part of Norway show a lower incidence than in other Nordic countries, but a

  9. Sundhedsorganisatorisk læreprocesser ved IKT-implementering

    DEFF Research Database (Denmark)

    Wentzer, Helle

    Præsenteret d. 15 november 2005 ved reception for Kroghstræde 1 og E-Learning Lab: Center for brugerdreven Innovation, design and Learning. Institut for Kommunikation, Det humanistiske Fakultet, Aalborg Universitet......Præsenteret d. 15 november 2005 ved reception for Kroghstræde 1 og E-Learning Lab: Center for brugerdreven Innovation, design and Learning. Institut for Kommunikation, Det humanistiske Fakultet, Aalborg Universitet...

  10. Orale senfølger af behandling for hoved-halscancer

    DEFF Research Database (Denmark)

    Assaad, Hala; Dynesen, Anja Weirsøe; Thisted, Lise Bjerrum

    2014-01-01

    Forebyggelse af orale senfølger af behandling for hoved-hals-cancer er vigtig for orale funktioner og livskvalitet Patienter, der er strålebehandlet for hovedhals-cancer, oplever betydelige senfølger i mundhulen; herunder xerostomi og hyposalivation, oral candidose, ubehag og smerte fra mundslimh...

  11. Ansvar for mangler ved salg af nedlagte landbrugsejendomme

    DEFF Research Database (Denmark)

    Edlund, Hans Henrik

    1999-01-01

    I artiklen redegøres for, at loven om forbrugerbeskyttelse ved erhvervelse af fast ejendom m.v. som udgangspunkt ikke gælder for fast ejendom undergivet landbrugspligt, og reglerne for, i hvilke tilfælde og hvornår landbrugspligten bortfalder, gennemgås. Dernæst vurderes muligheden for, at sælger...... af nedlagte landbrugsejendomme alligevel kan aftale med købere, at loven skal gælde, således at sælgerne opnår ansvarsfrihed for faktiske mangler ved bygningerne, selv om landbrugspligten (endnu) ikke er bortfaldet....

  12. Cyberangreb vil blive ved med at koste kassen

    DEFF Research Database (Denmark)

    Ørholst, Henrik

    2018-01-01

    Klumme. Oprydningen kostede næsten to mia. kr., da A.P. Møller-Mærsk sidste år blev udsat for et cyberangreb. En stribe andre virksomheder blev også ramt. Den ikoniske virksomhed klarede sig ved bl.a. at bruge WhatsApp og andre kommunikationskanaler.......Klumme. Oprydningen kostede næsten to mia. kr., da A.P. Møller-Mærsk sidste år blev udsat for et cyberangreb. En stribe andre virksomheder blev også ramt. Den ikoniske virksomhed klarede sig ved bl.a. at bruge WhatsApp og andre kommunikationskanaler....

  13. Svært ved grammatikken - del 2

    DEFF Research Database (Denmark)

    Kristensen, Line Burholt; Boye, Kasper

    2016-01-01

    Denne artikel er anden del af en artikelserie om baggrunden for grammatiske vanskeligheder. Den første artikel (bragt i Logos nr. 75) forklarede hvorfor grammatik er vigtigt for mennesker, og hvorfor det er vigtigt at have en teori om grammatik når man skal afgrænse, undersøge og behandle...... grammatiske vanskeligheder. Artiklen viste også at en klar og praktisk anvendelig definition er nødvendig, men at eksisterende traditionelle teorier giver uklare kriterier for forskellen på grammatik og leksikon. I denne anden del af artikelserien præsenterer vi en ny teori om grammatisk status (Boye & Harder...

  14. Adfærdsændringer og omkostninger ved FFT

    DEFF Research Database (Denmark)

    Scavenius Sonne-Schmidt, Christoffer; Lindberg, Malene Rudolf

    2018-01-01

    Implementering af en ny indsats indebærer en afvejning af gevinster og omkostninger. Denne sammenfatning beskriver unges og voksnes udvikling henover et indsatsforløb med FFT og vurderer omkostningerne ved at implementere og drive et FFT-team. Dette er sammenfatning del I. Her opsummeres resultat...

  15. Fair values ved første indregning i regnskabet?

    DEFF Research Database (Denmark)

    Thinggaard, Frank; Nilsson, Sven-Arne

    2007-01-01

    Denne artikel fortsætter gennemgangen og vurderingen af argumentationen, i  IASBs  diskussions-rapport (DP) om mulige målegrundlag, der kan benyttes ved første indregning. DP'et peger entydigt på, at aktiver og forpligtelser bør måles til fair values, såfremt disse kan opgøres tilstrækkeligt...

  16. Genetablering af skov på stormfaldsarealer ved naturlig foryngelse

    DEFF Research Database (Denmark)

    Brunner, Andreas; Petersen, Flemming Rune

    foryngelse i forsøget blev registreret intensivt de første fire år efter stormfaldet i 1999. Resultaterne er foreløbige på grund af den korte tidshorisont, men viser, at det er muligt at genetablere skov på stormfaldsarealer ved hjælp af naturlig foryngelse. Foryngelsen kan i vid udstrækning bygge på de...

  17. Forældretilstedeværelse ved modtagelse og behandling af tilskadekomne og akut syge børn er formentlig hensigtsmæssig

    DEFF Research Database (Denmark)

    Jensen, Pia Bredahl; Lomholt, Margrethe; Larsen, Claus Falck

    2011-01-01

    This review studies the literature on the effects of parental presence during treatment of injured and acutely ill children. Parents wish to stay with their child, and clinicians increasingly find it beneficial, probably correlated with increased experience. Studies indicate that the treatment...... of the child is not compromised by parental presence but only a few quasi-randomised, quantitative studies have been published, and many circumstances concerning parental presence have not been investigated sufficiently....

  18. Strømmålinger for ny forbindelse over Limfjorden i Lindholmlinien ved Aalborg

    DEFF Research Database (Denmark)

    Burcharth, Hans F.; Larsen, Torben

    På foranledning af "Undersøgelsesgruppen af 1. maj 1975", repræsenteret ved Rambøll og Hannemann A/S, Nørresundby har laboratoriet i november og december udført en række strømmålinger i området mellem Egholm og jernbanebroen i Limfjorden ved Aalborg med henblik på at fremskaffe et grundlag...... for vurderingen af besejlingsforholdene ved en kommende ny forbindelse over limfjorden ved lindholmlinien. Ved undersøgelsens planlægning har medvirket civilingeniør J. C. Schmidt, Rambøll og Hannemann A/S, ingeniørdocent H. F. Burchart og civilingeniør Torben Larsen. Herværende rapport er udarbejdet af Torben...

  19. Miljøundersøgelser ved Maarmorilik 1997

    DEFF Research Database (Denmark)

    Johansen, P.; Riget, F.; Asmund, G.

    Produktionen i bly-zink minevirksomheden i Maarmorilik ophørte i 1990. Miljøtilstanden i området er siden blevet undersøgt årligt ved indsamling og analyse for bly og zink i havvand samt lav og dyr fra området. Denne rapport præsenterer resulta-terne af de undersøgelser, som blev udført i 1997. I...... forhold til tidligere år var undersøgelserne i 1997 af mindre omfang, idet nogle elementer i det undersøgelsesprogram, som er planlagt udført efter minens lukning, ikke udføres hvert år. Spredning af bly og zink med støv fra minevirksomheden er undersøgt ved at indsamle og analysere lavarten Cetraria...... fleste tilfælde tydeligt lavere end i det lav, der naturligt vokser på den pågældende station. Forklaringen herpå er sandsynligvis, at det bly og zink der måles i naturligt voksende lav er akkumuleret i lavet over flere år, mens det der måles i transplanteret lav fortrinsvis repræsenterer det metal, der...

  20. Energi- og miljøvurdering ved renovering

    DEFF Research Database (Denmark)

    Holleris Petersen, E.

    En afprøvning af pc-værktøjet BEAT 2000's viser, at BEAT 2000 er et velegnet værktøj, der umiddelbart kan anvendes til energi- og miljøvurdering af renoveringssager. BEAT 2000 er afprøvet dels på renovering med energibesparende foranstaltninger i form af solfangere, solvægge og ventilationsanlæg...... med varmegenvinding, dels på mere traditionel renovering af små, utidssvarende lejligheder. En udbygning af datagrundlaget, især for alternative energibesparende løsninger og de materialer, der indgår, vil kunne reducere tidsforbruget ved definition af de utraditionelle og usædvanlige bygningsdele...

  1. Fair values ved første indregning i regnskabet?

    DEFF Research Database (Denmark)

    Thinggaard, Frank; Nilsson, Sven-Arne

    2007-01-01

    IASB har publiceret en diskussionsrapport, i hvilken mulige målegrundlag, der kan anvendes ved første indregning i regnskabet, bliver afvejet i forhold til hinanden. Rapporten konkluderer, at fair values så vidt muligt bør anvendes, såfremt disse værdier kan opgøres tilstrækkeligt pålideligt. I...... modsat fald skal virksomhederne vælge et målegrundlag som substitut for fair values, der kan opgøres pålideligt. Substituttet skal være mest mulig konsistent med fair values, og anvendes på en måde, som bedst muligt afspejler det, som en måling til fair value sigter efter (the fair value measurement...

  2. Karpaltunnelsyndrom: Prognostiske og økonomiske forhold ved endoskopisk operation

    DEFF Research Database (Denmark)

    Meldgaard, Anette

    Formål: At identificere prognostiske faktorer for genoptagelse af arbejde og normalisering af funktions¬niveau efter endoskopisk operation for karpaltunnelsyndrom. At vurdere de økonomiske konse¬kvenser i forhold til traditionel åben operation i en cost-effectiveness analyse med sparede syge......-tions¬tilfredshed samt symptom- og funktionsscore blev udfyldt. Udfra en simpel erhvervskorrigeret OR blev de signifikante prognostiske faktorer identificeret ved multipel logistisk regression. Her-udover blev der gennemført en cost-effectiveness analyse af endoskopisk operation i forhold til kon-ventionel åben...... operation. Effekten beregnedes som et vægtet gennemsnit af forskellen i antal post-operative sygedage estimeret i randomiserede kliniske undersøgelser af endoskopisk operation versus åben operation. Resultater: Den gennemsnitlige funktionsscore faldt fra 2,3 til 1,4 postoperativt (SD 0,8) og den gen...

  3. Life and consciousness – The Vedāntic view

    Science.gov (United States)

    Shanta, Bhakti Niskama

    2015-01-01

    In the past, philosophers, scientists, and even the general opinion, had no problem in accepting the existence of consciousness in the same way as the existence of the physical world. After the advent of Newtonian mechanics, science embraced a complete materialistic conception about reality. Scientists started proposing hypotheses like abiogenesis (origin of first life from accumulation of atoms and molecules) and the Big Bang theory (the explosion theory for explaining the origin of universe). How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from Nothing (as proposed by Stephen Hawking, among others), proves to be dissembling, since the quantum vacuum can hardly be considered a void. In modern science, it is generally assumed that matter existed before the universe came to be. Modern science hypothesizes that the manifestation of life on Earth is nothing but a mere increment in the complexity of matter — and hence is an outcome of evolution of matter (chemical evolution) following the Big Bang. After the manifestation of life, modern science believed that chemical evolution transformed itself into biological evolution, which then had caused the entire biodiversity on our planet. The ontological view of the organism as a complex machine presumes life as just a chance occurrence, without any inner purpose. This approach in science leaves no room for the subjective aspect of consciousness in its attempt to know the world as the relationships among forces, atoms, and molecules. On the other hand, the Vedāntic view states that the origin of everything material and nonmaterial is sentient and absolute (unconditioned). Thus, sentient life is primitive and reproductive of itself – omne vivum ex vivo – life comes from life. This is the scientifically verified law of experience. Life is essentially cognitive and conscious. And, consciousness, which is fundamental, manifests itself in the gradational forms of all

  4. Life and consciousness - The Vedāntic view.

    Science.gov (United States)

    Shanta, Bhakti Niskama

    2015-01-01

    In the past, philosophers, scientists, and even the general opinion, had no problem in accepting the existence of consciousness in the same way as the existence of the physical world. After the advent of Newtonian mechanics, science embraced a complete materialistic conception about reality. Scientists started proposing hypotheses like abiogenesis (origin of first life from accumulation of atoms and molecules) and the Big Bang theory (the explosion theory for explaining the origin of universe). How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from Nothing (as proposed by Stephen Hawking, among others), proves to be dissembling, since the quantum vacuum can hardly be considered a void. In modern science, it is generally assumed that matter existed before the universe came to be. Modern science hypothesizes that the manifestation of life on Earth is nothing but a mere increment in the complexity of matter - and hence is an outcome of evolution of matter (chemical evolution) following the Big Bang. After the manifestation of life, modern science believed that chemical evolution transformed itself into biological evolution, which then had caused the entire biodiversity on our planet. The ontological view of the organism as a complex machine presumes life as just a chance occurrence, without any inner purpose. This approach in science leaves no room for the subjective aspect of consciousness in its attempt to know the world as the relationships among forces, atoms, and molecules. On the other hand, the Vedāntic view states that the origin of everything material and nonmaterial is sentient and absolute (unconditioned). Thus, sentient life is primitive and reproductive of itself - omne vivum ex vivo - life comes from life. This is the scientifically verified law of experience. Life is essentially cognitive and conscious. And, consciousness, which is fundamental, manifests itself in the gradational forms of all

  5. Business information literacy: informasjonskompetanse ved Handelshøyskolen BI

    Directory of Open Access Journals (Sweden)

    Sigrid Gimse

    2010-07-01

    Full Text Available For å bli en informasjonskompetent student innenfor en internasjonal akademisk handelshøgskole, er det spesielle ferdigheter man må opparbeide seg. Det er ikke de samme kravene til hva en må kunne ved Odontologisk fakultet som ved BI, så heller ikke i bibliotekets sfære. De ferdighetene vi er på jakt etter å utvikle hos våre studenter er generiske for handelshøyskoler verden over, men allikevel er begrepet ”Business Information Literacy” et ganske nytt begrep, og som så mye annet hentet fra USA. Vi synes det er et spennende begrep, all den tid det definerer hva som er kravene, utover den enkelte handelshøyskoles sfære. Vi tror at det kommer til å etableres en standard for denne kompetansen i USA snart, men før dette er klart har vi sett på hva begrepet betyr for oss. Det har nemlig ledet oss mot en særegen undervisnings- og bibliotekpedagogikk. Tilføyelsen ”Business” til begrepet informasjonskompetanse kommer selvsagt på toppen av den generelle definisjonen, som vi også ”bekjenner” oss til og prøver å utvikle hos våre studenter og faglige. Begrepet springer ut av BIs fagområder der kravene til ”Business Information Literacy” kan innebære: • Kunne innhente emnespesifikk fag- og forskningslitteratur i relevante bibliografiske kilder • Kunne innhente makroøkonomiske data nasjonalt og internasjonalt • Kunne innhente forbrukerdemografiske data • Kunne innhente data typiske for markedsanalyse • Kunne innhente data innen bedrifts- industri- og bransjeanalyse • Kunne innhente finansielle data • Kunne bruke juridiske kilder • Kunne inkorporere funn i egne oppgaver etter akademisk standard Hva gjør vi for å utvikle disse ferdighetene hos våre studenter? Hvilke tiltak setter vi verk? Hva gjør handelshøyskoler verden over? Mange bibliotek utvikler i dag elæringsmateriale for å kunne nå det store antall studenter. Dette er også underveis hos oss.

  6. Oprensning af forureningen på depotet ved Høfde 42 ved hjælp af nul-valent jern

    DEFF Research Database (Denmark)

    Fjordbøge, Annika Sidelmann; Kjeldsen, Peter; Petersen, Peter Alfred

    Rapporten beskriver forsøg med nul-valent jern på forurenet vand og sediment fra depotet ved Høfde 42 på Harboøre Tange. Resultaterner viser, at parathion og malathion hurtigt og fuldstændigt bliver omdannet til langt mindre toksiske forbindelser, og endvidere nedbrydes mange af de tilstedeværende...

  7. Implementering af e-læring ved danske universiteter

    Directory of Open Access Journals (Sweden)

    Birgitte Heiberg

    2005-05-01

    Full Text Available

    Første gang publiceret i UNEV nr. 6: Organisering af e-læring, oktober - december 2005, red. Jørgen Gomme, Birgitte heiberg, Jens Dørup og Ambrosia Hansen. ISSN 1603-5518.

    Lige siden de første computere kom til landet har der været projekter, som tilsigtede at understøtte undervisning og læring ved hjælp af IKT. Understøttelsen har varieret som en bred vifte af forskellige former for medieanvendelse og grader af interaktion. Tilsvarende er diverse former for IKT-støttet undervisning og læring med forskellige betegnelser dukket op: Computer-Based Training (CBT, Computer Assisted Learning (CAL, Computer Supported Collaborative Learning (CSCL, Web-based Learning (WBL, blended learning, online læring, fleksibel læring, fjernundervisning, distribueret og åben uddannelse, m. fl.

  8. Hvilken rolle spiller hybrid shopping i kundereisen ved kjøp av kosmetikk?

    OpenAIRE

    Varem, Andrea; Nervik, Lene

    2017-01-01

    Temaet for denne bacheloroppgaven er hybrid shopping i kundereisen ved kjøp av kosmetikk. Etter en omfattende gjennomgang av eksisterende teori rundt kundereisen fikk vi et inntrykk av at det er et gap i forskningen knyttet til kundereisen ved kjøp av kosmetikk, på tross av størrelsen på dette markedet. Det vi fant av teori på feltet var i stor grad basert på kvantitative undersøkelser, og vi ønsker derfor å belyse kundereisen i denne konteksten gjennom et kvalitativt forskningsdesign. Med ut...

  9. For bestemmelse af drivhusgasudledning ved udtagning/Ekstensivering af landbrugsjorder på kulstofrige lavbundsjorder

    DEFF Research Database (Denmark)

    Gyldenkærne, Steen; Greve, Mogens Humlekrog

    Sammenfatning: Rapporten beskriver hvordan man kan beregne ændringen i drivhusgasemissionen ved omlægning af landbrugsjord til naturarealer. Rapporten er primært rettet mod tilskudsordningen vedr. udtagning af organiske lavbundsjorde, men kan også anvendes i andre sammenhænge. Rapporten anvender de...

  10. Miljøundersøgelser ved Maarmorilik 1999-2000

    DEFF Research Database (Denmark)

    Møller, P.; Asmund, G.; Johansen, P.

    I rapporten dokumenteres og vurderes forureningstilstanden ved den nedlagte blyzinkmine i Maarmorilik på baggrund af prøveindsamling i området i 1999 og 2000. Undersøgelserne viser, at der stadig frigives bly og zink fra kilder i området, men at miljøpåvirkningen efter minens lukning er betydeligt...

  11. Akutte dødsfald ved tvangsfastholdelse af svært hyperaktive personer

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Thomsen, Jørgen Lange

    2012-01-01

    må henføres til et syndrom som betegnes excited delirium syndrome (EDS), en akut indsættende tilstand karakteriseret ved en hyperaktiv og voldelig adfærd, næsten overmenneskelig styrke og immunitet for smerte. Obduktion viser ikke forandringer som kan forklare dødsfaldet. Årsagen til EDS er ukendt...

  12. Miljøoptimering af afvaskning ved tryk med vandfortyndbar flexotrykfarve

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Helweg, Christian; Pedersen, Anne Rathmann

    Rapporten beskriver praksis ved afvaskning af vandfortyndbare flexotrykfarver i emballageindustrien og anviser muligheder for indførelse af renere teknologi til reduktion af spildevandsbelastningen. Anbefalingerne omfatter a) udformning af farveværker med henblik på effektiv tømning af farve og e...

  13. ABC and VED Analysis of the Pharmacy Store of a Tertiary Care Teaching, Research and Referral Healthcare Institute of India.

    Science.gov (United States)

    Devnani, M; Gupta, Ak; Nigah, R

    2010-04-01

    The ABC and VED (vital, essential, desirable) analysis of the pharmacy store of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, was conducted to identify the categories of items needing stringent management control. The annual consumption and expenditure incurred on each item of pharmacy for the year 2007-08 was analyzed and inventory control techniques, i.e. ABC, VED and ABC-VED matrix analysis, were applied. The drug formulary of the pharmacy consisted of 421 items. The total annual drug expenditure (ADE) on items issued in 2007-08 was Rs. 40,012,612. ABC analysis revealed 13.78%, 21.85% and 64.37% items as A, B and C category items, respectively, accounting for 69.97%, 19.95% and 10.08% of ADE of the pharmacy. VED analysis showed 12.11%, 59.38% and 28.51% items as V, E, and D category items, respectively, accounting for 17.14%, 72.38% and 10.48% of ADE of the pharmacy. On ABC-VED matrix analysis, 22.09%, 54.63% and 23.28% items were found to be category I, II and III items, respectively, accounting for 74.21%, 22.23% and 3.56% of ADE of the pharmacy. The ABC and VED techniques need to be adopted as a routine practice for optimal use of resources and elimination of out-of-stock situations in the hospital pharmacy.

  14. Sport og medierettigheder

    DEFF Research Database (Denmark)

    Jakobsen, Søren Sandfeld

    2014-01-01

    Kapitlet behandler en række medie-, immaterial- og konkurrenceretlige aspekter ved overdragelse af tv-rettigheder til store sportsbegivenheder.......Kapitlet behandler en række medie-, immaterial- og konkurrenceretlige aspekter ved overdragelse af tv-rettigheder til store sportsbegivenheder....

  15. Intensiv musik- og psykomotorisk gruppeterapi m. flygtninge

    DEFF Research Database (Denmark)

    Telcs, Cathrine

    2014-01-01

    Evaluering af gruppemusikterapi i kombination med psykomotorisk behandling med 3 traumatiserede flygtninge ved hjælp af spørgeskemaer ( WHOQOL) og interviews.......Evaluering af gruppemusikterapi i kombination med psykomotorisk behandling med 3 traumatiserede flygtninge ved hjælp af spørgeskemaer ( WHOQOL) og interviews....

  16. A.R.T. – Aggression Replacement Training

    DEFF Research Database (Denmark)

    Harbo, Lotte Junker; Domben, Eskil

    2015-01-01

    Artiklen indeholder en kort introduktion, eksemplificeret ved case, af det manualbaserede program til behandling af udadreagerende unge Aggression Replacement Training.......Artiklen indeholder en kort introduktion, eksemplificeret ved case, af det manualbaserede program til behandling af udadreagerende unge Aggression Replacement Training....

  17. Bedre ældrepleje - ved hjælp af Marte Meo metoden

    DEFF Research Database (Denmark)

    Meyer, Helle; Schjoldager, Helle Højbo

    Projektet (forløb efteråret 2008 - foråret 2009) havde til formål at give personalet ved boformer for borgere med demens indsigt i og redskaber til at kommunikere med borgeren på en for begge parter anerkendende måde - ved hjælp af Marte Meo metoden. Det konkluderes at implementering af Marte Meo...... metoden har medført, at personalet har udviklet deres samspil og kommunikation med borgerne på en måde, der synes at fremme borgerens trivsel, værdighed og livsglæde og dermed bidrage til en øget livskvalitet. En række faktorer der henholdsvis fremmer og hæmmer implementeringen af Marte Meo metoden...

  18. ABC-VED analysis of expendable medical stores at a tertiary care hospital.

    Science.gov (United States)

    Kumar, Sushil; Chakravarty, A

    2015-01-01

    The modern system of medicine has evolved into a complex, sophisticated and expensive treatment modality in terms of cost of medicines and consumables. In any hospital, approximately 33% of total annual budget is spent on buying materials and supplies including medicines. ABC (Always, Better Control)-VED (Vital, Essential, Desirable) analysis of medical stores of a large teaching, tertiary care hospital of the Armed Forces was carried out to identify the categories of drugs needing focused managerial control. Annual consumption and expenditure data of expendable medical stores for one year was extracted from the drug expense book, followed by classification on its annual usage value. Subsequently, the factor of criticality was applied to arrive at a decision matrix for understanding the need for selective managerial control. The study revealed that out of 1536 items considered for the study, 6.77% (104), 19.27% (296) and 73.95% (1136) items were found to be A, B and C category items respectively. VED analysis revealed that vital items (V) accounted for 13.14% (201), essential items (E) for 56.37% (866) and desirable accounted for 30.49% items (469). ABC-VED matrix analysis of the inventory reveals that only 322 (21%) items out of an inventory of 1536 drugs belonging to category I will require maximum attention. Scientific inventory management tools need to be applied routinely for efficient management of medical stores, as it contributes to judicious use of limited resources and resultant improvement in patient care.

  19. Consequences of increased NOx emission to air during the treatment of gas from Kvitebjoern and the Haltenbanken Soer at Kaarstoe; Konsekvenser av oekte NOx utslipp til luft ved behandling av gass fra Kvitebjoern og Haltenbanken Soer paa Kollsnes

    Energy Technology Data Exchange (ETDEWEB)

    Guerreiro, Cristina

    1998-11-01

    This report discusses the consequences of increasing the emission to air of nitrogen oxides if landing facilities for North-Sea gas is developed at Kaarstoe, Norway. Three alternatives are considered. The pollution from such a facility comes in addition to the existing plant at Kaarstoe, the Aasgard terminal and the planned gas power station. The report considers concentrations in air, deposition to ground, impact on acidification of surface water and the impact of the natural environment. Concentrations in air have been calculated. The assessment of the deposition of nitrogen oxides to ground, the assessment of acidification of surface water and the assessment of the impact on flora and fauna are based on a consequence analysis for a gas power station at Kaarstoe. The influence of the development of the Kaarstoe plant on the local environment is largely determined by the amount of emissions and the tallness of the chimney. The regional impact is not very dependent on the emission conditions and the global impact is independent of the emission conditions and, to some extent, of the emission site.

  20. Beretning for Bulbrogård 2013 (BU2013), aristokratisk kompleks. NM I journalnr. 7701/94 Store Fuglede sogn, Ars herred, (Holbæk Amt) Region Sjælland. Sted nr. 03.01.06 – sb. nr. 102 Kort nr. 1413 III NØ Beretning for undersøgelse aristokratisk kompleks fra det 6. – 7. årh. ved Bulbrogård ved Tissø

    DEFF Research Database (Denmark)

    Bican, Josefine Franck

    Undersøgelserne er en fortsættelse af de afsluttende undersøgelser ved Bulbrogård fra 2012 og er en del af forskningsprojektet Førkristne Kultpladser ved forskningsprofessor Lars Jørgensen, Nationalmuseet. Lokaliteten blev opdaget i 1995 i forbindelse med forundersøgelsen på bopladsområdet ved Ti...

  1. Consciousness, Cognition and the Cognitive Apparatus in the Vedānta Tradition

    Science.gov (United States)

    Balasubramanian, R.

    2011-01-01

    A human being is a complex entity consisting of the Self (also known as Consciousness), mind, senses and the body. The Vedānta tradition holds that the mind, the senses and the body are essentially different from the Self or Consciousness. It is through consciousness that we are able to know the things of the world, making use of the medium of the mind and the senses. Furthermore, the mind, though material, is able to reveal things, borrowing the light from consciousness. From the phenomenological point of view, we have to answer the following questions: how does one know the mind/the mental operations/the cogitations of the mind? Does the mind know itself? Is it possible? There is, again, the problem of the intentionality of consciousness. Is consciousness intentional? According to Vedānta, consciousness by its very nature is not intentional, but it becomes intentional through the mind. The mind or the ego is not part of the consciousness; on the contrary, it is transcendent to consciousness. It is difficult to spell out the relation between consciousness and the mind. How does consciousness, which is totally different from the mind, get related to the mind in such a way that it makes the latter capable of comprehending the things of the world? The Vedānta tradition provides the answer to this question in terms of the knower-known relation. Consciousness is pure light, self-luminous by its very nature, that is, although it reveals other objects, it is not revealed by anything else. When Sartre describes it as nothingness, bereft of even ego, it is to show that it is pure light revealing objects outside it. PMID:21694962

  2. Hvad ved vi? Hvad vil vi? Hvad gør vi?

    DEFF Research Database (Denmark)

    Frederiksen, Lisbeth Angela Lunde

    2011-01-01

    fokus på professionslæring og kompetenceudvikling i et livslangt læringsperspektiv. DEtte kan gøres ved at man i kommunerne tænker i tre forskellige former for mentoring de første to år.: en til en menoring, supervision og transparen det første år og gruppementoring det andet år efterfulgt af peer......-group mentoring de følgende år som led i dels den kommunale skoleudvikling, dels i lærernes fortsatte professionelle udvikling....

  3. Tilsetningsstoff og tekniske hjelpestoff ved produksjon av filet av hvitfisk. Faglig sluttrapport

    OpenAIRE

    Lorentzen, Grete Elisabeth

    2017-01-01

    Målsettingen med dette prosjektet har vært å øke den generelle kunnskapen om bruk av tilsetningsstoffer og tekniske hjelpestoffer ved produksjon av hvitfiskfilet. I prosjektet er det gjennomført et litteraturstudium på hvilken effekt ulike tilsetningsstoffer har på fiskefilet. Deretter er det laget en veileder hvor målet har vært å gi en lettfattet og oversiktlig informasjon om hvilke tilsetningsstoffer det er lov å bruke, hvilken effekt de har, og eksempler på praktisk bruk av tilsetningssto...

  4. Anvendelse af MIP ved kildekarakterisering og vurdering af nedbrydning af chlorerede opløsningsmidler

    DEFF Research Database (Denmark)

    Broholm, Mette Martina; Janniche, Gry Sander; Damgaard, Ida

    2014-01-01

    Membrane Interface Probing (MIP) er et 'direct push' screeningsværktøj, som kan anvendes ved karakterisering af forurenede grunde. Karakterisering af kildeområder med chlorerede opløsningsmidler (som DNAPL) udgør et vigtigt led i udviklingen af den konceptuelle forståelse, som er essentiel...... for risikovurdering og valg af afværgestrategi. Integreret karakterisering med en række metoder for direkte såvel som indirekte dokumentation af DNAPL i moræneler, herunder MIP, er beskrevet i Kerrn-Jespersen et al. (2013). Det samlede DNAPL-karakteriseringsprojekt er beskrevet i detaljer i Janniche et al. (2013). En...... vurdering af anvendte detektorer for MIP er foretaget af Olsson (2013). Ved karakterisering af forurening med bl.a. chlorerede opløsningsmidler er der behov for en vurdering af forureningssammensætning og nedbrydning. Tilsvarende vurdering er nødvendig, når udviklingen af stimuleret reduktiv dechlorering...

  5. Internationale kommunikationseffekter ved fremsendelse af danske vidensregnskaber på engelsk til kunder i Storbritannien og Tyskland: Forskningsbaggrund og -design

    DEFF Research Database (Denmark)

    Skaates, Maria Anne

    2003-01-01

    Formålet med dette Working Paper er at fastlægge en metodologi for et kommende studium af de internationale kommunikationseffekter ved fremsendelse af danske vidensregnskaber på engelsk til kunder i Storbritannien og Tyskland. I det følgende afsnit vil der derfor blive redegjort generelt for, hvad...

  6. Infiltrationsanæstesi som postoperativ smertebehandling ved hoftenær femurfraktur - et igangværende studie

    DEFF Research Database (Denmark)

    Bech, Rune Dueholm

    2008-01-01

    pertrochantær femurfraktur og collum femoris fraktur inkluderes. 50 patienter indgår i hver af de to diagnose-grupper (to delstudier). Ved randomisering tildeles patienterne hhv. Ropivacain eller placebo (NaCl), der gives som 1 peroperativ og 6 postoperative bolusinstillationer via et kateter, som fjernes efter...

  7. Monitering, modellering og miljøvurdering af fuldskala afværge af TCE fourening ved stimuleret reduktiv deklorering

    DEFF Research Database (Denmark)

    Westergaard, Claus; Lemming, Gitte; Janniche, Gry Sander

    På Sortebrovej 26 i Tommerup blev der i 2006 gennemført afværgeforanstaltninger ved stimuleret reduktiv deklorering (SRD) ved injektion af donor og bakterier i kildeområdet med henblik på at oprense en forurening med TCE. Kildeområdet befinder sig 10-20 m u. t. i sandet og opsprækket moræneler...... gunstige forhold for nedbrydning af de klorerede ethener ved reduktiv deklorering. Der ses da også en klar dominans af nedbrydningsprodukterne DCE og VC samt ethen og ethan i grundvandet. I nogle boringer, ses dog en stagnerende omsætning af TCE og DCE i grundvandet. Årsagen her til kan være, at donoren...... da også fordoblet fra 2008 til 2010. Der er observeret zoner med betydelig omsætning af TCE, hvor cis-DCE dominerer, og der ses generelt VC og ethen centralt i disse zoner. Koncentrationsniveauet af fermenteringsprodukter er aftaget og består ved en sandslire (B370 K1) alene af acetat og methan...

  8. Letbeton 1

    DEFF Research Database (Denmark)

    Meyer, E.V.; Nerenst, P.

    Denne SBI-anvisning giver en orienterende gennemgang af alle de forhold ved letbeton, som det er gavnligt for de fleste af byggeriets folk at have viden om. Den behandler fortrinsvis letbetoner fremstillet ved skumdannelse og ved luftudviklilng. Selve fremstillingsprocessen er kort beskrevet, sål...

  9. Kommunikation ved brug af mobile enheder med digital video i idræt

    DEFF Research Database (Denmark)

    Langagergaard Rødbro, Lise; Elbæk, Lars

    2012-01-01

    I artiklen redegøres kort for et projekt, som førte frem til en videoplatform, der er et bud på et ’lukket YouTube’, hvor video filmet med smartphone direkte kan uploades til, og med funktioner specifikt udviklet til skolens idrætsundervisning. Med afsæt i systemisk kommunikationsteori analyseres...... observations- og interviewda-ta for at belyse den kommunikation, der foregår ved brug af platformen. Senere diskuteres resultaterne ud fra kommunikationstrekanten, og der skitseres en model for videostøttet undervisning i idræt ud fra Batesons kommunikations- og læringsniveauer. Gennem analyser af platformens...

  10. Ved du, hvad der er i dine varer, når du handler?

    DEFF Research Database (Denmark)

    Phillip, Anja; Smith, Viktor

    2016-01-01

    I supermarkedet på vej hjem køber du ind til madpakken. Ved kølemontren med pålæg ser du en pakke Gårdlykke Hønsesalat. ... Måske vælger du den uden at tænke nærmere over hvorfor, eller fordi emballagen og navnet får hønsesalaten til at fremstå lokal, hjemmelavet eller økologisk. ... Alt dette ba...... bakkes op af resultaterne fra årelang forskning på CBS, hvor universitetets forskergruppe Fair-Speak har undersøgt emballagernes måde at påvirke forbrugerne til at købe produktet....

  11. Numerisk modellering af formfyldning ved støbning i selvkompakterende beton

    DEFF Research Database (Denmark)

    Spangenberg, Jon

    dækker over mange emner. I denne afhandling er der fokuseret på tre af dem ved hjælp af Finite Difference Method (FDM) / Finite Volume Method (FVM) baserede Computational Fluid Dynamics (CFD) modeller udviklet i både FLOW-3D og MATLAB. Den første undersøgelse fokuserer på de komplikationer der er knyttet...... til at forudse separation under fyldning i SKB støbninger. De to FDM/FVM baserede CFD modeller afviger fra hinanden via deres tilslags repræsentation, som var en diskret metode (envejs momentum kobling) for den første og en skalar metode for den anden. Det viste sig, at det var mindst omfattende...

  12. VEDS-Automated system for inspection of vehicles and containers for explosives and other threats

    International Nuclear Information System (INIS)

    Gozani, T.; Liu, F.; Sivakumar, M.

    2004-01-01

    Many parts of national infrastructures around the world are very vulnerable to terrorist threats in the form of large vehicle bombs. The larger bomb, the larger is the damage and its extent. The number of containers and vehicles crossing land or sea ports of entry is huge. Tough the probability is low, any vehicle may contain a threat. Any system addressing these enormous security tasks should obviously be based on excellent human intelligence to focus the attention on a much smaller number of high-risk containers and vehicles. These containers must then be subjected to a thorough and reliable inspection for the threats.Viable security system must incorporate a credible and effective inspection to achieve its purposes. It should have high performance and be operationally acceptable. This means the system must possess high detection capabilities, low false positive rate, fast response and provide automatic decision eliminating the need for human interpretation. Ancore has developed a range of new inspection devices, which are highly suitable for the above tasks. All the systems are automatic, material specific, high performance for a wide range and type of threats. Some of them are also highly modular, and compact. Some of the systems are fixed, other are relocatable, or fully mobile. The presentation will discuss Ancore's VEDS (Vehicle Explosive Detection System) which detects bulk explosives (expandable also to radiological and nuclear threats)) in marine containers, trucks and cars. The compact and rugged nature of the VEDS sensor makes it suitable for many forms of conveyance: mobile (van mounted), portal, forklift mounted, or mounted on container unloading rig. The physics principles of the system and some recent applications and results will be presented

  13. Modulbaserte kurs for PhD-studentar ved Matematisk-naturvitskapleg fakultet, UiB

    Directory of Open Access Journals (Sweden)

    Hege Folkestad

    2010-07-01

    Full Text Available Universitetsbiblioteket i Bergen har utarbeidd eit modulbasert kurs for PhD-studentar ved Matematisk-naturvitskapleg fakultet. Biblioteket har samarbeidd med fakultetet om innhald, tidspunkt og annonsering, for i størst mogeleg grad å nå studentane og tilpasse til deira behov. Kurset er ikkje obligatorisk, men anbefalast sterkt av fakultetet, som vektlegg overførbare ferdigheiter hjå doktorandane. Evalueringane så langt er svært gode, og kurset vidareførast derfor i noverande form. Generell teori er skilt ut, og presentert i tre plenumssesjonar over til saman 5 timar: 1 Strukturelle trekk ved vitskapleg litteratur, generell søketeknikk, reiskapar for søk og gjenfinning, oppdateringstenester og evaluering av skriftleg materiale 2 Siteringsstatistikk 3 Publisering, inklusive opphavsrettslege problemstillingar, Open Access, sjølvarkivering og institusjonelle arkiv. Stoff som knyttast til praktiske ferdigheiter vert presentert i workshop-form for mindre grupper i kursrom med PC-tilgang. Vi tilbyr såleis valfrie, separate, 1-2 t workshops i databasesøking, inndelt etter plattform (i.e. alle Thomson-Reutersbasane samla, alle CSA-basane samla osb.. Vidare tilbyr vi 2 t workshops i referansehandtering (EndNote. For nye brukarar vektleggast innlegging av referansar, val av stil, generering av referanselister og bruk av EndNote med Word, for erfarne brukarar vektleggast fulltekstnedlasting, oppretting av bibliografi frå fleire dokument, samarbeid om EN-bibliotek og oppretting av nye stilar. Med modulbasert kurs står studentane fritt til å stå over kjent stoff, kombinere databasekurs eller EndNote-nivå, eller kome tilbake for modular som er meir relevante seinare i løpet. I denne presentasjonen leggast vekta på plenumssesjon 1 og workshop-modulane.

  14. ANALYSE AV SAMVARIASJON MELLOM MÅLT ARBEIDSBELASTNING (NAS) OG DEN SUBJEKTIVE OPPLEVELSEN AV ARBEIDSBELASTNINGEN (NASA-TLX) VED INTENSIVAVDELINGER

    OpenAIRE

    Graarud, Vibeke

    2015-01-01

    SAMMENDRAG Sykehus generelt og intensivavdelinger spesielt er under økende press for å kunne drive god og riktig ressursforvaltning. Dermed øker også behov for å kunne dokumentere intensiv-avdelingenes aktivitet og ressursbehov. Nursing Activities Score (NAS) blir ved flere av landets intensivavdelinger brukt som scoringsverktøy for arbeidsbelastning. Det er et verktøy som har til hensikt å kartlegge behovet for antall sykepleiere per pasient. Det er i Norge flere sykepleiere per intensivpasi...

  15. Hvordan ser den ost ud, som De ikke ved, De vil elske om to år?

    DEFF Research Database (Denmark)

    Grunert, Klaus G.

    2006-01-01

    Kender de Deres "latente behov"? Det gør De selvfølgelig ikke. Det er jo definitionen af begrebet: Et latent behov er et behov, som man ikke ved, at man har, men som kommer til overfladen, når man møder det rigtige produkt, som opfylder netop dette behov. Latente behov vedrører derfor den ost, vi...

  16. Sammenligning av to blodprøver fra samme person analysert ved to laboratorier

    Directory of Open Access Journals (Sweden)

    Aage Tverdal

    2009-10-01

    Full Text Available  INNLEDNINGEpidemiologiske undersøkelser av lipidnivået hosbefolkningen er helt avhengig av at analysemetodeneholder stabilt nivå over flere år. Dette er lettest å oppnåhvis man hele tiden benytter ett laboratorium, oghjerte-karundersøkelsene til Statens helseundersøkelserhar konsekvent benyttet Klinisk kjemisk avdeling,Ullevål sykehus. Ulike hensyn kan likevel tilsi at andrelaboratorier benyttes. Undersøkelsene til Universiteteti Tromsø som har har vært gjennomført fire ganger iperioden 1973-1995, har vært utført ved Kliniskkjemisk avdeling, Regionsykehuset i Tromsø. Helseundersøkelseni Nord-Trøndelag 1995-1997 harbenyttet Sentrallaboratoriet, Innherred sykehus. I dettearbeidet viser vi hvor store forskjellene blir hvisfeltlagene sender prøver fra samme person til ulikelaboratorier. Vi har undersøkt forskjellene mellomRegionsykehuset i Tromsø og Ullevål sykehus, ogmellom Innherred sykehus og Ullevål sykehus.

  17. Hvis du ikke har plads ved bordet – så tag en stol med dig

    DEFF Research Database (Denmark)

    Evron, Lotte Orr

    2017-01-01

    Sådan lød opfordringen fra sygeplejersker i høje politiske positioner på ministerie- og NGO-niveau til deltagerne på ICN 2017 kongressen i Barcelona. Hovedbudskabet var, at vi som sygeplejersker skal bruge vores faglighed, viden og magt til at skabe mere sundhed for alle verdens borgere. Sygeplej......Sådan lød opfordringen fra sygeplejersker i høje politiske positioner på ministerie- og NGO-niveau til deltagerne på ICN 2017 kongressen i Barcelona. Hovedbudskabet var, at vi som sygeplejersker skal bruge vores faglighed, viden og magt til at skabe mere sundhed for alle verdens borgere....... Sygeplejersker har både viden og faglighed til at skabe forandring og flytte sundhed på det lokale og globale plan. Desværre tager al for få sygeplejersker magten og skaber sig en plads ved det bord, hvor de store sundhedspolitiske beslutninger tages....

  18. Kan nye VHS udbrud i regnbueørred forebygges ved vaccination eller avl?

    DEFF Research Database (Denmark)

    Lorenzen, Niels

    laboratoriet ved forskellige temperaturer med godt resultat. En mindre afprøvning under dambrugsforhold har også givet gode resultater. Før det kan komme på tale bruge vaccinen ude, skal den dog godkendes af sundhedsmyndighederne. Egtvedsyge findes i flere lande i Europa og er kendt som en meget tabsvoldende......Tørlægning og desinfektion har traditionelt været brugt til at bekæmpe virussygdommen Egtvedsyge (VHS) i danske ørred-dambrug og lige nu regnes VHS for udryddet. Det har dog vist sig, at der hos vilde fiskebestande i havet findes VHS virus, som under visse omstændigheder må forventes at kunne...... koder for virusets overfladeprotein. Når plasmidet sprøjtes ind i en fisks rygmuskel, vil det blive optaget af en del af muskelcellerne på injektionsstedet, dog uden at plasmidets gener kommer ind i cellernes egne kromosomer. Fidusen er, at disse muskelceller herefter kan lave virusproteinet på samme...

  19. Grasping at ontological straws: overcoming reductionism in the Advaita Vedānta-Neuroscience dialogue.

    Science.gov (United States)

    Kaplan, Stephen

    2009-01-01

    Contemporary neuropsychology reveals that the parietal lobe contains neurons that are specifically attuned to the act of grasping and this act may be fundamental to the establishment of the phenomenal boundaries between subject and object. Furthermore, alterations to this process, such as the hypoactivation of this region during meditation or the hyperactivation associated with schizophrenia, may eliminate or confuse, respectively, the phenomenal boundaries between subject and object. Traversing disciplines, the Advaita Vedānta school of Hinduism traces some of its key terms for subject and object to the verbal root grah, to grasp. The subject is literally the grasper. Furthermore, the practice of asparśa yoga, the yoga of no-touch, is aimed at stopping, hypoactivating, the grasping process in order to transcend all subject-object boundaries. This paper will argue that while we have not uncovered an identity of thought, we have uncovered a confluence of ideas between these two disciplines. We will see that this confluence of ideas has not pitted the believer against the critic-not forced us into the great reductionism debate that has dominated so much of the interchange between religious studies and the sciences. This case study will illuminate some of the methodological ways around this reductionism battle and also the boundaries of both disciplines for the intellectual benefit of each.

  20. Tilgængelige boliger - indretning

    DEFF Research Database (Denmark)

    Sigbrand, Lone; Jensen, Philip Henrik

    Anvisningen behandler indretning af boliger, så de er tilgængelige for personer med funktionsnedsættelser.Denne anvisning behandler indretning af boliger, så de er tilgængelige for personer med funktionsnedsættelser. Ved at følge anvisningen sikrer man sig, at man lever op til kravene om tilgænge...

  1. Behandling af demenssygdomme--hvem skal behandles?

    DEFF Research Database (Denmark)

    Hasselbalch, Steen; Kampmann, Jens Peter

    2009-01-01

    Recommendations for treatment with specific antidementia drugs in Denmark are given on the basis of recent evidence. Such evidence supports treatment of mild to moderate Alzheimer's Disease (AD) with acetylcholinesterase inhibitors (AchEI), and moderate to severe AD with memantine. Combination...... therapy with these drugs can be considered in moderate AD. Dementia with Lewy bodies and Parkinson's disease with dementia should be treated with rivastigmine. There is not sufficient evidence to recommend treatment with AchEI or memantine in pure vascular dementia or frontotemporal dementia...

  2. Undersøgelse af Magnuseffekten på en cylinder ved brug af dimensionsanalyse og empirisk data

    OpenAIRE

    Lauritzen, Ann Katrine Toft; Clarke, Danijel Charles; Ajslev, Mikkel Zielinski; Victor, David Eklund; Bisgaard, Stefan; Thomsen, Malina Masik Talita Isaksen; Larsen, Emil Ellegaard

    2016-01-01

    Projektet har til formal at undersøge tværkraften, der optærder på en roterende cylinder, sombevæger sig relativt til et fluid. Tværkraften kender man som Magnuskraften, og er oftest beskreveti forhold til en roterende sfære. En mangel på viden om Magnuskraftens opførsel på cylindrehar inspireret os til projektet. Dette emne undersøges gennem dimensionsanalyse og ved brugaf empirisk data. Der indledes med et kapitel om grundlæggende teori indenfor fluiddynamikfor at give en kvalitativ forståe...

  3. Spa-typing av stammer av Staphylococcus aureus fra blodkulturer analysert ved UNN Tromsø 2007-2008

    OpenAIRE

    Midtgard, Anette

    2011-01-01

    Bakgrunn: Staphylococcus aureus er et av de vanligste patogenene som kan skape sykdom hos mennesket. Mange av oss er bærere av bakterien i nese eller hals, og det er vist at persisterende bærere har høyere risiko for å utvikle S. aureus-infeksjoner enn andre. De fleste S. aureus-infeksjonene blant bærere er forårsaket av pasientens egen bakteriestamme. Materiale og metode: 140 blodkulturisolater fra pasienter med S. aureus bakteriemi analysert ved Avdeling for mikrobiologi og smitte...

  4. Måleegenskaper ved den norske versjonen av ADHD Rating Scale IV, Skoleversjon (ADHD-RS-IV Skole)

    OpenAIRE

    Kornør, Hege; Bøe, Tormod

    2011-01-01

    - Beskrivelse. ADHD-RS-IV Skole er et spørreskjema som skal fylles ut av lærere eller førskolelærere for å fange opp ADHD-symptomer hos barn og ungdom. Spørreskjemaet har 18 ledd med fire svaralternativer. Det tar under 20 minutter å fylle ut. Hovedskalaen og de to delskalaene skåres ved å summere enkeltskårer. Kompetansekrav for bruk av ADHD-RS-IV inkluderer generell opplæring i testbruk, samt yrkesstatus som psykolog, lege, annet helsepersonell med utdanning på mastergradsnivå, spesialpe...

  5. Måleegenskaper ved den norske versjonen av ADHD Rating Scale – IV Hjemmeversjon (ADHD-RS-IV Hjemme)

    OpenAIRE

    Kornør, Hege; Bøe, Tormod

    2011-01-01

    - Beskrivelse. ADHD-RS-IV Hjemme er et spørreskjema som skal fylles ut av mor, far, verge eller besteforeldre for å fange opp ADHD-symptomer hos barn og ungdom. Spørreskjemaet har 18 ledd med fire svaralternativer. Det tar under 20 minutter å fylle ut. Hovedskalaen og de to delskalaene skåres ved å summere enkeltskårer. Kompetansekrav for bruk av ADHD-RS-IV inkluderer generell opplæring i testbruk, samt yrkesstatus som psykolog, lege, annet helsepersonell med utdanning på ...

  6. Generelle aspekter ved mediereception? – Et bud på en multidimensional model for analyse af kvalitative receptionsinterviews

    Directory of Open Access Journals (Sweden)

    Kim Schrøder

    2003-09-01

    Full Text Available Findes der generelle aspekter ved receptionen af medieprodukter, som det kan være analytisk frugtbart at orientere sig efter, og som man altid bør belyse, når man analyserer kvalitative receptionsdata – og måske også allerede når man skal planlægge det empiriske feltarbejde i et em- pirisk receptionsprojekt? Denne artikel bygger på, at dette spørgsmål kan besvares bekræftende, og fremlægger et bud på, hvordan en multi- dimensional model for kvalitativ receptionsanalyse kunne se ud.

  7. Elevers produktion af multimodale tekster. Hvad ved vi og hvad mangler vi?

    Directory of Open Access Journals (Sweden)

    Vibeke Christensen

    2016-09-01

    Full Text Available I Danmark er der med de nye Fælles Mål fra 2014 indført et krav om, at eleverne skal kunne lave større multimodale produktioner. Også i de øvrige skandinaviske lande indgår arbejde med multimodale tekster med forskellig betegnelse i læreplanen for modersmålsfaget. Det er således relevant at undersøge, hvad man ved om elevers produktion af multimodale tekster. Denne artikel bidrager med en gennemgang af nordisk forskning inden for området og med udblik til den øvrige vestlige verden. Teoretisk beskrives multimodalitet med udgangspunkt i New London Groups programartikel fra 1996 og den udvikling af multimodalitet, som gruppen omkring Kress og van Leeuwen har bidraget med. Resultaterne af forskningsgennemgangen præsenteres i fem temaer: terminologi, didaktik, undervisning, elevudbytte og vurdering. Diskussion pågår løbende inden for hvert tema, og der peges på didaktiske perspektiver.Nøgleord: multimodale tekster, tekstkompetence, elevpræstation, skrive-pædagogik, produktion, vurderingAbstractIn the new curriculum for the subject Danish from 2014, it is a requirement that students should be able to create major multimodal productions. Working with multimodal texts in the mother tongue subject is included in the curricula for all three Scandinavian countries. Therefore, it is relevant to consider what is already recognized as students’ production of multi-modal texts. This article offers a brief review based on the Nordic research together with a brief look towards the rest of the Western world’s research on multimodality. This paper’s theoretical foundation is based on the New London Group’s article from 1996, “Pedagogy of Multiliteracies: Designing Social Futures”, and the development of multimodality that re-searchers and scholars surrounding Kress and van Leeuwen have contributed with. The results of the research will be presented in the following five themes: terminology, education, teaching, pupil performance

  8. Risici ved ophævelsen af kvotebekendtgørelsen for NOx og SO2 for kraftværkerne

    DEFF Research Database (Denmark)

    Nielsen, Ole-Kenneth; Nielsen, Malene

    Rapporten belyser de mulige konsekvenser ved ophævelse af ”Bekendtgørelse om begrænsning af udledning af svovldioxid og kvælstofoxider fra kraftværker”, nr. 885 af 18. december 1991. (Herefter kvotebekendtgørelsen). Det er foretaget en basisfremskrivning af NOx-emissionen frem til 2025 for de vær...

  9. Growth of the endocrine pancreas

    DEFF Research Database (Denmark)

    Gaarn, Louise Winkel

    Diabetes er karakteriseret ved en enten absolut eller relativ mangel paa insulin producerende ß-celler (henholdsvis type 1 og 2 diabetes). Den mest oplagte behandling ville vaere at genskabe den funktionelle ß-cellemasse ved enten regenerering eller celle terapi og dermed genindfoere normal gluco...

  10. Behandling af brandskader

    DEFF Research Database (Denmark)

    Lang, Christian Lyngsaa; Partoft, Søren; Astrup, Jakob

    2015-01-01

    This paper aims to clarify the newly revised guidelines regarding burn injuries as to assist medical personnel dealing with burns. The Department of Burns at Rigshospitalet is the main burn centre in Denmark, and thus creates the National Guidelines of burns treatment. The new guidelines have...

  11. Korrekt behandling af forfrysninger

    DEFF Research Database (Denmark)

    El-Charnoubi, Waseem Ghulam; Bonde, Christian; Alsbjørn, Bjarne F

    2011-01-01

    Frostbite is rare in Denmark and is often associated with psychiatric conditions or drug- and alcohol abuse. It is seen regularly in countries with an arctic climate and tradition for outdoor activities such as skiing and climbing. The past winter in Denmark was long and cold, so we may see this ...... this phenomenon more frequently in the future. We report two cases from the winter 2009/2010 and summarize the pathophysiology and briefly present the treatment strategy....

  12. Behandling af infantile spasmer

    DEFF Research Database (Denmark)

    Kjærsgård, Lars; Rasmussen, Niels

    2006-01-01

    Infantile spasms (IS) are characterised by neurodevelopmental regression, a unique type of seizures and a hypsarrhythmic EEG pattern. Studies recommend the medical treatment of IS as a positive short-term outcome with respect to the spasms and in the resolution of the hypsarrhythmia. However...

  13. Behandlingsresistent depression kan behandles

    DEFF Research Database (Denmark)

    Vinberg, Maj; Levinsen, Mette Frandsen; Kessing, Lars Vedel

    2011-01-01

    Depression is considered resistant when two treatment attempts with antidepressants from different classes fail to produce significant clinical improvement. In cases of treatment-resistant depression, it is recommended to reevaluate the diagnosis, clarify comorbidity, substance abuse and lack of ...

  14. Samfundserhvervet pneumoni--behandling

    DEFF Research Database (Denmark)

    Andersen, Ljubica; Brock, Birgitte; Jakobsen, Preben

    2008-01-01

    Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S....... pneumoniae requires T>MIC above 40-50%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment...

  15. Behandling af Dupuytrens kontraktur

    DEFF Research Database (Denmark)

    Raundrup Kornø, Maj; Søe, Niels Henrik; Dahlin, Lars B

    2015-01-01

    Dupuytren’s disease treatment Dupuytren’s disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Gen...

  16. Behandling af rolandisk epilepsi

    DEFF Research Database (Denmark)

    Miranda, Maria Jose; Ahmad, Banoo Bakir

    2017-01-01

    Recent literature indicates, that rolandic epilepsy/epilepsy of childhood with centrotemporal spikes may not be as benign as previously assumed. This study investigates the existing evidence, which describes the treatment effects on seizure frequency as well as improvement of cognition in childre...

  17. Behandlingsresistent depression kan behandles

    DEFF Research Database (Denmark)

    Vinberg, Maj; Levinsen, Mette Frandsen; Kessing, Lars Vedel

    2011-01-01

    Depression is considered resistant when two treatment attempts with antidepressants from different classes fail to produce significant clinical improvement. In cases of treatment-resistant depression, it is recommended to reevaluate the diagnosis, clarify comorbidity, substance abuse and lack...... of compliance. Regarding treatment, evidence is sparse, but switching to a different antidepressant, and combination or augmentation with another agent, admission and treatment with ECT are the options. The choice of treatment must be based on the characteristics of the depression, the severity of treatment...

  18. Betydning af centraliseret behandling

    DEFF Research Database (Denmark)

    Højgaard, Liselotte

    2006-01-01

    hospital organizations. Centralization with a focus on efficiency and low cost, as well as decentralization combined with the loss of university hospital functions, will further challenge the conditions of clinical research already seen worldwide and also experienced in Denmark....

  19. Behandling af lokaliseret prostatacancer

    DEFF Research Database (Denmark)

    Jakobsen, Henrik; Iversen, Peter; Mikines, Kári J

    2007-01-01

    vesicles performed as an open procedure or laparoscopically, external beam radiation therapy, or implantation of radioactive seeds into the prostate (brachytherapy). In older patients with good prognostic factors, active surveillance should be considered. The various therapeutic modalities are reviewed...

  20. Behandling af lokaliseret prostatacancer

    DEFF Research Database (Denmark)

    Jakobsen, Henrik; Iversen, Peter; Mikines, Kári J

    2007-01-01

    vesicles performed as an open procedure or laparoscopically, external beam radiation therapy, or implantation of radioactive seeds into the prostate (brachytherapy). In older patients with good prognostic factors, active surveillance should be considered. The various therapeutic modalities are reviewed....

  1. Behandling af hypertermi

    DEFF Research Database (Denmark)

    Mørch, Sofie Søndergaard; Andersen, Johnny Dohn Holmgren; Bestle, Morten Heiberg

    2017-01-01

    syndrome, a few endocrine emergencies as well as numerous intoxications. Rapid diagnosis and prompt cooling are pivotal, since the condition triggers a cascade of metabolic events which may progress to irreversible injury or death. Ice-water immersion and evaporative cooling are the methods of choice....

  2. "Toore puuga kütmine on raiskamine ..." = "Att elda med sur ved är slöseri ..." : [luuletused] / Gunnar D. Hansson ; tlk. Mati Sirkel

    Index Scriptorium Estoniae

    Hansson, Gunnar D.

    2004-01-01

    Sisu: "Toore puuga kütmine on raiskamine ..." = "Att elda med sur ved är slöseri ..."; "Esimest päeva rändab tuul ..." = "Första dagen vandrar vinden ..."; "Päike tuli lähemale ..." = "Solen kom närmare ..."; "Nagu oleks kõik möödas ..." = "Som om allt vore över ..."

  3. En liten høyskole som tenker stort: tiltak mot fusk og plagiat ved Høgskolen i Hedmark

    Directory of Open Access Journals (Sweden)

    Ellen Nierenberg

    2010-07-01

    Full Text Available Høgskolen i Hedmark har satt i gang en del tiltak mot fusk og plagiat, og vi vil gjerne dele våre ressurser og erfaringer med andre undervisningsinstitusjoner. Dette er relevant til to av konferansens temaer: fagreferentens rolle og undervisning i biblioteket. HH's tiltak mot fusk og plagiat inkluderer: • Undervisning i informasjonskompetanse - Høgskolebiblioteket • Kurs i kildebruk og plagiat, "Kilder og kildebruk" • Søkekurs • Synliggjøring av bibliotekressurser/-kurs • Brosjyre til ansatte • Bibliotekets websider om informasjonskompetanse • Nettressurser • Bibliotekets websider • Eksempelsamlingen i APA-standard • "Skriving av faglige tekster - En guide for studenter" • Webside om plagiat og opphavsrett • Fronter • Videoforelesning - "Kilder og kildebruk" • PowerPoint - "Kilder og kildebruk" • Tekstgjenkjenningsprogrammet Ephorus • Vurdering • Elektronisk prøve • Obligatorisk skriveoppgave • Rutinebeskrivelse for tiltak mot fusk og plagiat på Høgskolen • Oppfølging av ikke-møtte studenter på "Kilder og kildebruk" • Vurdering i etterkant av kurset • Bruk av Ephorus • Konsekvenser for fusk Høgskolens tiltak skal forebygge fusk og plagiat ved å gi alle nye studenter tilstrekkelig informasjon om kravene for riktig kildebruk og om konsekvensene for fusk. Høgskolebiblioteket har en sentral rolle i dette arbeidet. Vår Informasjonskompetansegruppe har utarbeidet mange nyttige ressurser, blant annet to-timers kurset "Kilder og kildebruk". Målet med kurset er å lære nye studenter å kritisk vurdere forskjellige typer kilder og bruke dem på korrekt måte i skriftlig arbeid. Kurset blir holdt av bibliotekarer på høgskolens fire campus, og etterfølges av et søkekurs tilpasset det enkelte studium. Antall plagiatsaker på HH har økt de siste årene, men dette kan skyldes bruk av Ephorus. Etter hvert som våre tiltak blir tatt i bruk ved alle studier, håper vi at antall saker blir

  4. Atrial fibrillation in the Danish population

    DEFF Research Database (Denmark)

    Hansen, Morten Lock

    2010-01-01

    . Evidensgrundlaget for at oral antikoagulations behandling (AK – behandling) nedsætter risikoen for tromboemboli er særdeles veldokumenteret. Derfor bør der i en korrekt behandling af patienter med atrieflimren, indgå en vurdering af, om der er indikation for AK – behandling. Flere studier har påvist en langsom og...... vaklende implementeringen af AK - behandlingen i daglig klinisk praksis. Mange atrieflimren patienter med indikation får ikke AK – behandling og mange uden indikation får det! Brug af AK - behandlingen kompliceres også af, at mange patienter med atreiflimren har indikation for trombocythæmmende behandling......, eksempelvis ved iskæmisk hjertesygdom. Hvor stor en blødningsrisiko man påfører patienten ved at kombinere clopidogrel, acetylsalicylsyre eller begge behandlinger med AK - behandling, er usikkert. I denne afhandling fokuseres på faktorer relateret til AK – behandling og de kliniske konsekvenser associeret til...

  5. Consequences of increased NO{sub x} emission to air during the treatment of gas from Kvitebjoern and the Haltenbanken Soer at Kaarstoe; Konsekvenser av oekte NO{sub x} utslipp til luft ved behandling av gass fra Kvitebjoern og Haltenbanken Soer paa Kollsnes

    Energy Technology Data Exchange (ETDEWEB)

    Guerreiro, Cristina

    1998-11-01

    This report discusses the consequences of increasing the emission to air of nitrogen oxides if landing facilities for North-Sea gas is developed at Kaarstoe, Norway. Three alternatives are considered. The pollution from such a facility comes in addition to the existing plant at Kaarstoe, the Aasgard terminal and the planned gas power station. The report considers concentrations in air, deposition to ground, impact on acidification of surface water and the impact of the natural environment. Concentrations in air have been calculated. The assessment of the deposition of nitrogen oxides to ground, the assessment of acidification of surface water and the assessment of the impact on flora and fauna are based on a consequence analysis for a gas power station at Kaarstoe. The influence of the development of the Kaarstoe plant on the local environment is largely determined by the amount of emissions and the tallness of the chimney. The regional impact is not very dependent on the emission conditions and the global impact is independent of the emission conditions and, to some extent, of the emission site.

  6. Anthracycline-induced cardiotoxicity. Changes in left ventricular function evaluated by radionuclide cardiography during and after epirubicin therapy and predictive value of the method for heart failure; Antracyclin-induceret kardiotoxicitet. Aendringer i venstre ventrikels funktion vurderet ved isotopkardiografi under og efter behandling med epirubicin, og metodens evne til at praediktere klinisk hjerteinsufficiens

    Energy Technology Data Exchange (ETDEWEB)

    Schaadt, Bente Krogsgaard

    1998-12-31

    Eighty-nine patients with breast cancer participated in this study of the left ventricular function determined by radionuclide cardiography before, during and after epirubicin treatment. Radiocardiography (MUGA = MUlti Gated Acquisition) was performed on patients in horizontal position after an intravenous injection of {sup 99m}Tc-labelled human serum albumin. Of these patients 67 were treated with at least 850 mg/m{sup 2} of the drug. Eight of the patients developed clinical signs of heart failure, whereas 59 did not. A fall in left ventricular ejection fraction (LVEF) was recorded during the first of the treatment period in both groups. The age was significantly higher and LVEF lower before epirubicin treatment in the group that developed heart failure, but the change in LVEF during treatment was of the same magnitude in the two groups. Whereas internationally recommended criteria for interruption of chemotherapy had low predictive values in these patients, a combination of 3 criteria: age {>=} 50 years, pre-treatment LVEF {<=} 0.60 and a fall in LVEF below 0.50 during epirubicin treatment yielded a high diagnostic value with regard to development of heart failure. The sensitivity and specificity of these criteria were 88% and 95%, respectively, and the predictive value of a positive and a negative test 70% and 98%. (au)

  7. Case report - curved femoral osteotomy for management of medial patellar luxation

    DEFF Research Database (Denmark)

    Allpass, Maja; Miles, James Edward

    2015-01-01

    Medial patellaluxation kan forårsages af femoral varus hos hund. Førhen har patienter med excessiv femoralvarus været korrigeret ved en lateralt placeret femoral kile-ostektomi. Her præsenteres en case, hvor en buet osteotomi blev anvendt til behandling af medial patellaluxation.......Medial patellaluxation kan forårsages af femoral varus hos hund. Førhen har patienter med excessiv femoralvarus været korrigeret ved en lateralt placeret femoral kile-ostektomi. Her præsenteres en case, hvor en buet osteotomi blev anvendt til behandling af medial patellaluxation....

  8. Komorbiditet ved marginal parodontitis

    DEFF Research Database (Denmark)

    Holmstrup, Palle; Damgaard, Christian; Olsen, Ingar

    2017-01-01

    Nærværende artikel præsenterer en oversigt over den foreliggende væsentligste viden om sammenhængen mellem marginal parodontitis og en række medicinske sygdomme, herunder hjerte-kar-sygdomme, diabetes mellitus, reumatoid arthritis, osteoporose, Parkinsons sygdom, Alzheimers sygdom, psoriasis og...

  9. Osteoporose ved Parkinsons sygdom

    DEFF Research Database (Denmark)

    Ezzatian-Ahar, Shabnam; Schwarz, Peter; Pedersen, Stephen Wørlich

    2015-01-01

    The risk of developing osteoporosis, as well as Parkinson's disease (PD) is increased with increasing age, resulting in increased risk of fracture, particularly hip fractures. Each one of these two conditions can be debilitating and affect the individual patient's quality of life negatively. PD...

  10. Cimetidinbehandling ved cancer ventriculi

    DEFF Research Database (Denmark)

    Tønnesen, H; Knigge, U P; Bülow, S

    1989-01-01

    The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo...

  11. Psykologiske aspekter ved overvaegt

    DEFF Research Database (Denmark)

    Madsen, Svend Aage; Grønbaek, Helle; Olsen, Hanne

    2006-01-01

    Although knowledge of the biological aspects of obesity is increasing very rapidly, psychological approaches are increasingly in demand. Psychological theory and research concerning the emotional and cognitive impacts of being obese, the psychological causes involved in obesity, and the psycholog......Although knowledge of the biological aspects of obesity is increasing very rapidly, psychological approaches are increasingly in demand. Psychological theory and research concerning the emotional and cognitive impacts of being obese, the psychological causes involved in obesity......, and the psychological elements of treatment and motivations for treatment are requested. There is no clear separation between the psychological factors that function as causes of obesity and the psychological effects of obesity. Rather, they appear to be related in a circle of interconnectedness. This is important...... to keep in mind when seeking ways to motivate and support obese patients....

  12. Neurologiske aspekter ved stammen

    DEFF Research Database (Denmark)

    Mertz, Line Bie; Østergaard, John R

    2006-01-01

    Stuttering is characterised by repetitions, prolongations and pausing while speaking. Researchers have looked for many explanations. However, the cause of stuttering remains unknown. In recent years, structural abnormalities in the speech-related structures of the central nervous system have been...... brought into focus as a cause of stuttering. Research has shown signs of a lateral hemisphere asymmetry, abnormalities in the basal ganglia, dysfunction in the supplementary motor area and/or a dysfunction in the coordination of the cerebellum. This article is a review of this part of the literature...

  13. Billeddiagnostik ved akut lungeemboli

    DEFF Research Database (Denmark)

    Hess, Søren; Madsen, Poul Henning; Jørgensen, Henrik Boel

    2005-01-01

    and echocardiography in acute pulmonary embolism and identified 562 articles, of which 16 original papers met our inclusion criteria. From these, we concluded that none of the modalities is applicable in every situation. Spiral computed tomography can confirm the diagnosis but cannot rule out subsegmental embolism....... With lung scintigraphy, perfusion imaging alone is probably sufficient and suited to both confirming and ruling out the diagnosis. Echocardiography should be reserved for patients with an emergent need for treatment and cannot rule out the diagnosis. Udgivelsesdato: 2005-Oct-10...

  14. Cancerrisiko ved topikale immunmodulatorer

    DEFF Research Database (Denmark)

    Deleuran, Mette; Zachariae, Claus; Thestrup-Pedersen, Kristian

    2009-01-01

    This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non...

  15. Hypofysefunktion ved haemokromatose

    DEFF Research Database (Denmark)

    Pedersen-Bjergaard, U; Thorsteinsson, B; Kirkegaard, B C

    1996-01-01

    A review of the literature on pituitary function in haemochromatosis is presented. In morphological studies pituitary iron deposition, in particular in gonadotropic cells, has been demonstrated. In a number of case series, insufficiency of pituitary gonadotropic secretion with clinical hypogonadism...

  16. Tryghed ved udskrivelse

    DEFF Research Database (Denmark)

    Gryet, Inger Markussen; Kjærsgaard-Andersen, Anne Marie

    Introduction According to international studies, a feeling of security is important for patients when discharge from the hospital. Feeling secure when discharged has been a national focus area in Denmark and national surveys show that about 12% of patients feel insecure when discharged. The nurses...... from a larger group of patients about factors related to the feeling of security and insecurity when discharged from the hospital. Objectives To gain knowledge about which patients feel insecure when discharged and what the reason is for this feeling of insecurity, to get ideas on how to improve...... the feeling of security at discharge for future patients. Methods An electronic questionnaire survey was developed and filled out via iPad before patients discharge from hospital and followed up by telephone interviews with a number of patients. Results 151 patients participated in the questionnaire survey...

  17. Ekstrakorporal oxygenering ved legionellapneumoni

    DEFF Research Database (Denmark)

    Uslu, Bülent; Steensen, Morten

    2009-01-01

    We present a case report with a 49-year-old woman with legionella pneumonia and fulminant respiratory failure. Despite maximal conventional respirator treatment with positive pressure ventilation, 100% oxygen and pharmacological treatment in an intensive care unit, further deterioration with hypo......We present a case report with a 49-year-old woman with legionella pneumonia and fulminant respiratory failure. Despite maximal conventional respirator treatment with positive pressure ventilation, 100% oxygen and pharmacological treatment in an intensive care unit, further deterioration...

  18. "Fordi man ved aldrig"

    DEFF Research Database (Denmark)

    Borchmann, Simon Uffe

    2015-01-01

    I denne artikel vil syntagmet aktivitetsbestemt sprogbrug blive udlagt fra en pragmatisk, funktionel lingvistisk synsvinkel. Syntagmet er særligt interessant fra denne synsvinkel fordi det synes at indebære et nyt sprogvidenskabeligt forskningsområde. Det er i det mindste det der vil blive argume...

  19. Aortahomograftoperationer ved svaer endokarditis

    DEFF Research Database (Denmark)

    Foghsgaard, S.; Kjaergard, H.K.; Bruun, Niels Eske

    2008-01-01

    INTRODUCTION: Severe endocarditis of the native aortic valve or a prosthetic valve with destruction of the cusps, paravalvular abscess formation and/or fistulas caused by aggressive bacteria has a mortality of almost 100% without surgery. The objective was to evaluate the results of treatment...... in an intravenous drug abuser was registered after 4 years. CONCLUSION: An aortic homograft in combination with intravenous antibiotics is an excellent treatment of severe endocarditis in the aortic valve or an aortic valve prosthesis Udgivelsesdato: 2008/5/5...

  20. Psykose ved affektive lidelser

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel

    2008-01-01

    Psychosis in affective disorder is prevalent as 15-20% of depressive patients and approximately 50% of manic patients present with psychotic features. Psychosis in conjunction with affective disorder has a poor prognosis. It is particularly so for depression where psychosis is associated...... with an increased risk of recurrence, development of bipolar disorder and suicide. It is still being debated whether these conditions reflect independent illness entities and their relationship to schizoaffective disorder and schizophrenia is also unresolved....

  1. Medicineringsfejl ved generisk substitution

    DEFF Research Database (Denmark)

    Rölfing, Jan

    2012-01-01

    Generic substitution is a major cause of medical mistakes in the general population. Danish legislation obligates pharmacies to substitute prescribed medicine with the cheapest equivalent formulation, despite variations in product name, packaging, shape and colour. Consequently, medical mistakes...... occur. Scientific evidence on the consequences of generic substitution is sparse. Call upon fellow health workers to report medical mistakes to the national entities and scientific peers, in order to increase awareness and scientific evidence about the problem....

  2. Mikrokirurgi ved plastikkirurgiske indgreb

    DEFF Research Database (Denmark)

    Bonde, Christian T; Jensen, Lisa Toft; Tos, Tina

    2016-01-01

    The most common indication for free flap surgery is breast reconstruction. Deep inferior epigastric perforator flaps are safe, quick and provide excellent cosmetic results. The reconstruction in head and neck cancer patients is more complex. The aims are preservation of function and appearance. F...

  3. Psykose ved affektive lidelser

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel

    2008-01-01

    Psychosis in affective disorder is prevalent as 15-20% of depressive patients and approximately 50% of manic patients present with psychotic features. Psychosis in conjunction with affective disorder has a poor prognosis. It is particularly so for depression where psychosis is associated with an ...... with an increased risk of recurrence, development of bipolar disorder and suicide. It is still being debated whether these conditions reflect independent illness entities and their relationship to schizoaffective disorder and schizophrenia is also unresolved Udgivelsesdato: 2008/11/10...

  4. Vejledning ved ambulancetransport

    DEFF Research Database (Denmark)

    Berlac, Peter Anthony; Wammen, Susanne; Giebner, Matthias

    2010-01-01

    , 2) minimize the occurrence of adverse events during transport, 3) ensure that accompanying staff are trained for and skilled in transfer and retrieval medicine and 4) encourage optimal utilisation of available competencies without unnecessarily draining hospital resources.......Inter-hospital transportation poses potential risks to staff and patients. The present guidelines recommend competency-based management dictated by the patient's clinical condition and medical requirements during transfer. The guidelines aim to: 1) improve patient and staff safety during transport...

  5. Medicinproblemer ved sektorskifte

    DEFF Research Database (Denmark)

    Christensen, Hanne Rolighed; Krølner, Bjørn K

    2009-01-01

    of responsibilities, lack of communication, frequent exchanges between synonymous and analogous drugs, polypharmacy, compliance issues and insufficient education and training of staff. There is an obvious need for a joint internet-based online prescription system covering all physicians. Udgivelsesdato: 2009-Mar......Prescribing involves careful considerations of outcome, duration of treatment and follow-up, and such considerations should be communicated to everyone involved in the medication process. Hospital admission and discharge involve a high risk of medication errors caused by unclear division...

  6. Operationsteknikker ved section

    DEFF Research Database (Denmark)

    Aabakke, Anna J M; Secher, Niels Jørgen; Krebs, Lone

    2014-01-01

    Caesarean section (CS) is a common surgical procedure, and in Denmark 21% of deliveries is by CS. There is an increasing amount of scientific evidence to support the different surgical techniques used at CS. This article reviews the literature regarding CS techniques. There is still a lack of evi...

  7. Modelling Aṣṭādhyāyī: An Approach Based on the Methodology of Ancillary Disciplines (Vedāṅga)

    Science.gov (United States)

    Mishra, Anand

    This article proposes a general model based on the common methodological approach of the ancillary disciplines (Vedāṅga) associated with the Vedas taking examples from Śikṣā, Chandas, Vyākaraṇa and Prātiśā khya texts. It develops and elaborates this model further to represent the contents and processes of Aṣṭādhyāyī. Certain key features are added to my earlier modelling of Pāṇinian system of Sanskrit grammar. This includes broader coverage of the Pāṇinian meta-language, mechanism for automatic application of rules and positioning the grammatical system within the procedural complexes of ancillary disciplines.

  8. Kan lignin omdannes til flydende brændstof?

    DEFF Research Database (Denmark)

    Nielsen, Joachim Bachmann; Jensen, Anders; Felby, Claus

    2015-01-01

    Ved en solvolytisk omdannelse af plantematerialet lignin til et flydende brændstof behandles det ved høj temperatur og højt tryk i et passende opløsningsmiddel. En sådan proces kan gennemføres ikke-katalytisk og være med til at skabe flydende brændsler baseret på vedvarende energikilder. Her...

  9. Grønne områders betydning for bymiljø og stress

    DEFF Research Database (Denmark)

    Hansen, Karsten B.

    2004-01-01

    Der er mange sundhedsmæssige fordele ved at opholde sig udendørs i grønne områder, især i forhold til at reducere stress. En række lande inkl. Sverige bruger allerede det grønne aktivt i forebyggelse og behandling af sygdomme. I Danmark er den første patienthave på vej til at blive en realitet ved...

  10. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over ...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates....

  11. Onkologisk behandling af meningeal carcinomatose

    DEFF Research Database (Denmark)

    Sulim, S.; Høyer, Morten

    2005-01-01

    Meningeal carcinomatosis (MC) occurs in 5-8% of cancer patients. In the       majority of cases, MC appears in patients with advanced disease. The       increase in incidence is probably caused by improved survival due to       improvements in systemic therapy and an increased awareness of MC among...

  12. Behandling af hydatidose med albendazol

    DEFF Research Database (Denmark)

    Magnussen, P; Gelletlie, R; Bygbjerg, Ib Christian

    1989-01-01

    of the patients had varying degrees of liver involvement which were reversible. Neutropenia did not occur. Various parameters for assessing the therapeutic effect are mentioned. Albendazol appears to be effective in the treatment of non-operable hydatid disease and to prevent recurrence after surgery....

  13. Stress og profylakse samt behandling

    DEFF Research Database (Denmark)

    Netterstrøm, Bo

    2012-01-01

    Prevention of stress should address the stressors and factors which modify the effect of these. At the community level legislation and agreements on the labour market are important tools. At the enterprise level policies to reduce stress and monitoring the psychosocial work environment has...... the first priority in prevention. Treatment of stress is often a long-term process involving diagnostic assessment, psycho-education and counselling. The Danish National Board of Health has published recommendations to both general practitioners and the public in this area....

  14. Farmakologisk behandling af psykotiske tilstande

    DEFF Research Database (Denmark)

    Fink-Jensen, A.; Larsen, J.T.; Nielsen, B.

    2008-01-01

    Antipsychotic medication has been used for more than fifty years and has brought a dramatic improvement in the treatment of psychotic diseases by removing or reducing the psychotic symptoms and thereby also allowing other treatment approaches to be used. However, an urgent need remains for new me...

  15. Den dysplastiske hofte II. Behandling

    DEFF Research Database (Denmark)

    Jacobsen, Steffen; Sonne-Holm, Stig

    2003-01-01

    The possibility of individualized treatment of residual dysplasia of the hip in childhood and adulthood has renewed the interest in this orthopaedic field and new procedures of treatment have been devised. This article reviews current knowledge of the treatment of the dysplastic hip....

  16. Diagnostik og behandling af fenylketonuri

    DEFF Research Database (Denmark)

    Bayat, Allan; Møller, Lisbeth Birk; Lund, Allan Meldgaard

    2015-01-01

    Primary phenylalanine hydroxylase deficiency, also known as phenylketonuria, results in accumulation of phenylalanine in the blood. Early identification and treatment prevents the majority of clinical sequelae to the disease, but psychological and neurodevelopmental problems can occur in some...

  17. Behandling af gener efter whiplash

    DEFF Research Database (Denmark)

    Rittig-Rasmussen, Bjarne; Kongsted, Alice; Carstensen, Tina

    2010-01-01

    Treatment of whiplash-associated disorders starts with a thorough clinical examination, which may be repeated after 1-3 weeks. For optimal results it is essential that the patient receives clear information about the condition and that any pain is treated effectively with analgesics. Risk factors...

  18. Udredning og behandling af papilsekretion

    DEFF Research Database (Denmark)

    Saltvig, Iselin; Perdawood, Frea Ramzi; Matzen, Steen Henrik

    2017-01-01

    Nipple secretion is a common condition; it can occur in men and women, and be uni- or bilateral. It is related to hormonal changes, physical stimulation, intracerebral processes and certain drugs, and it is divided into three types: galactorrhoea, clear/bloody or viscous. Only the clear/bloody type...

  19. stausartikel: behandling af subcutane abscesser

    DEFF Research Database (Denmark)

    Hardgrib, Nina; Petersen, Klaus Kjær

    2017-01-01

    Simple subcutaneous abscesses are common, and we have examined the literature concerning the ideal treatment of subcutaneous abscesses. We recommend radical debridement with removal of all pus, the abscess wall and any necrosis. If primary suture is chosen, preoperative antibiotics should be admi...

  20. Kirurgisk behandling af cancer pancreatis

    DEFF Research Database (Denmark)

    Bergenfeldt, Magnus; Hansen, Carsten Palnaes; Mortensen, Michael Bau

    2010-01-01

    Surgery remains the only hope for cure in pancreatic cancer. The most common procedures are reviewed. Postoperative morbidity and mortality below 30% and 5%, respectively, are the standard. The benefit of extended lymph node dissection and portal-mesenteric vein resection is dubious. Selected pat...

  1. Kongenit hyperinsulinisme - diagnostik og behandling

    DEFF Research Database (Denmark)

    Christesen, Henrik Thybo; Fuglsang Bruun, Maria; Hedegaard Christoffersen, Stine

    2011-01-01

    -fluoro-L-dihydroxyphenylalanine positron emission tomography/computed tomography and peroperative microscopy of frozen section allows surgeons to resect the focal lesion instead of performing subtotal pancreatectomy. Milder CHI, sometimes difficult to diagnose, is treated conservatively. In spite of all improvements, cerebral...

  2. Præhospital behandling

    DEFF Research Database (Denmark)

    Larsen, C F; Jørgensen, H R; Nielsen, J R

    1990-01-01

    by the Danish National Board of Health was also tested. Experience from abroad and recent Danish trial arrangements demonstrate the positive effect of extended professional prehospital treatment. The authors consider, therefore, that an ambulance law is required as this would ensure better and more uniform...

  3. Behandling af den hypoterme patient

    DEFF Research Database (Denmark)

    Kjærgaard, Benedict; Rudolph, Søren Finnemann; Lucas, Alexander

    2008-01-01

    Treatment of the hypothermic patient depends more on the clinical condition than on the core temperature. Unconscious patients need thorough investigation, and they can often be rewarmed with warm water in the pleural cavities. Cardiac arrest requires cardio pulmonary rescue until rewarming can b...

  4. Rekommandation for behandling af paracetamolforgiftning

    DEFF Research Database (Denmark)

    Clemmesen, J O; Ott, P; Dalhoff, K P

    1996-01-01

    Based on recent reports concerning the efficacy of N-acetylcysteine (NAC) in paracetamol (acetaminophen) poisoning, guidelines for treatment and control of these patients are reviewed by a study group under the Danish Association for the Study of the Liver. It is recommended that NAC-treatment...... is initiated immediately after referral and continued for 36 hours in all cases. Further NAC-treatment should not be discontinued before a decrease in INR has been observed....

  5. Diagnose og behandling af binyrebarkkarcinom

    DEFF Research Database (Denmark)

    Abildgaard, Julie; Pappot, Helle; Petersen, Peter Meidahl

    2013-01-01

    Adrenocortical carcinomas (ACC) are rare tumours responsible for only 0.02% of the total number of malignant diseases. However the ACC are aggressive with a mean fiveyears survival of 20-50% and are often associated with increased production of adrenocortical hormones. The effect of the treatment...... is controversial and often based on small retrospective series or expert opinions. Centralization, international attention and collaboration in the treatment of ACC are mandatory. Randomized clinical trials are needed to determine the best treatment strategy in order to increase survival in patients with ACC....

  6. Behandling af astma hos gravide

    DEFF Research Database (Denmark)

    Akram, Iram; Ulrik, Charlotte Suppli; Johnsen, Claus Rikard

    2016-01-01

    Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least ...

  7. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates....

  8. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates. Udgivelsesdato: 2009-Jun-8...

  9. Udredning og behandling af hoste

    DEFF Research Database (Denmark)

    Çolak, Yunus; Laursen, Lars Christian

    2013-01-01

    Cough is frequently a reason for seeing a doctor. Cough has a wide range of causes and the diagnosis can be difficult to make. Cough is often benign and self-limiting but can also be the first sign of malignancy. Especially chronic cough reduces the patients' quality of life. The purpose of this ...

  10. Behandling af insulinom med alkoholsklerosering

    DEFF Research Database (Denmark)

    Schnack, Christina; Christensen, Carina Ørts; Beck-Nielsen, Henning

    2012-01-01

    The efficacy and safety of endoscopic ultrasound (EUS)-guided alcohol ablation of an insulinoma in a patient not candidate for surgery is being evaluated. A 89 year-old male patient with insulinoma and serious cardiac disease was treated with EUS-guided alcohol ablation. The only complication...... was a slight degree of pancreatitis. Two months after the ablation values of plasma glucose and serum pro-insulin were normalized. EUS-guided alcohol ablation is a safe and efficient alternative to surgical resection of insulinomas in poor surgical candidates....

  11. Beretning for Bulbrogård 2012 (BU2012), aristokratisk kompleks. NM I journalnr. 7701/94 Store Fuglede sogn, Ars herred, (Holbæk Amt) Region Sjælland. Sted nr. 03.01.06 – sb. nr. 102 Kort nr. 1413 III NØ Beretning for undersøgelse aristokratisk kompleks fra det 6. – 7. årh. ved Bulbrogård ved Tissø

    DEFF Research Database (Denmark)

    Bican, Josefine Franck

    De afsluttende undersøgelser på Bulbrogård 2012 bød på nye og overraskende resultater: Bulbrogård har fået en ny fase. Som det nogle gange sker, bliver man mere forvirret end oplyst ved at få mere viden – dette er også tilfældet her. Den ny hal (hus 7) kan være det manglende arkitektoniske bindel...

  12. Dødelig venlafaxinforgiftning

    DEFF Research Database (Denmark)

    Pedersen, Julie Steen; Munck, Lars Kristian

    2014-01-01

    Venlafaxin er en serotonin- og noradrenalingenoptagelseshæmmer, der er godkendt til behandling af depressioner og angsttilstande. Symptomer ved forgiftning er serotonergt syndrom, generaliserede krampeanfald, rabdomyolyse samt akut lever-, hjerte- og nyresvigt. Der findes ingen antidot. Med afsæt i...

  13. Industry and the environment-practical applications of environmental management approaches in business proceedings of the 3rd conference of the Nordic Business Environmental Management Network, March 28-30, 1996, Aarhus, Denmark

    DEFF Research Database (Denmark)

    Ulhøi, John Parm; Madsen, Henning

    1996-01-01

    Bogen indeholder refereed papers fra en international miljøledelseskonference ved Scandinavian Center Århus, arrangeret af forfatterne. Konferencen havde delegerede fra ialt 17 lande. Bogen, der indledes med en indledning skrevet af redaktørerne, er inddelt i en række hovedafsnit, der behandler e...

  14. Civil Procedure in Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik; Petersen, Lars Lindencrone

    Værket gennemgår regler og praksis for civilprocessen ved danske domstole, ligesom også voldgift i Danmark behandles. Der skrives ud fra begge forfatteres betydelige teoretiske viden og praktiske erfaring på området. I vidt omfang inddrages og analyseres retspraksis i form af afgørelser fra dansk...

  15. Kontraktetablering i supervision

    DEFF Research Database (Denmark)

    Mortensen, Karen Vibeke; Jacobsen, Claus Haugaard

    2007-01-01

    Kapitlet behandler kontraktetablering i supervision, et element, der ofte er blevet negligeret eller endog helt forbigået ved indledningen af supervisionsforløb. Sikre aftaler om emner som tid, sted, procedurer for fremlæggelse, fortrolighed, ansvarsfordeling og evaluering skaber imidlertid trygh...

  16. Bedre boligplaner

    DEFF Research Database (Denmark)

    Ranten, K.; Vedel-Petersen, F.

    Meddelelsen behandler brugskravene til boligens plan. Først opstilles detaljerede arealkrav ud fra beboernes aktiviteter, dernæst beskrives hvordan aktiviteterne kan tilgodeses og fordeles i planen, og endelig sammenfattes kravene i oversigter og checklister, der tjener som værktøj ved vurdering ...

  17. ”Hospitalet bliver aldrig et godt sted”

    DEFF Research Database (Denmark)

    Haa, Berit Pedersen; Aagaard, Hanne

    2014-01-01

    Ved ankomsten i Skadestuen er børn ofte chokerede, utrygge, angste og har smerter. De træder ind et ukendt sted, hvor der er fremmede lyde og lugte - og hvor de skal undersøges og behandles. Formålet med udviklingsprojektet ”Hospitalsklovne i Skadestuen” er at undersøge, hvorvidt hospitalsklovne ...

  18. Foreløbige retsmidler

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2008-01-01

    Artiklen behandler foreløbige retsmidler ved EF-domstolen, fx mod Danmarks fortsatte byggeri af Storebæltsbroen i strid med fællesskabsretlige udbudsregler eller mod ikrafttrædelsen af en forbundslov om tyske motorvejsafgifter i strid med kravet om ligebehandling af inden- og udenlandske vognmænd...

  19. Fichte

    DEFF Research Database (Denmark)

    Nielsen, Carsten Fogh

    2016-01-01

    af en udefrakommende andethed. Disse tre temaer behandles med udgangspunkt i tre tekster, som Fichte skrev og publicerede umiddelbart før og under sin ansættelse som professor ved universitetet i Jena i perioden 1794- 1799: "Über den Begriff der Wissenschaftslehre oder der sogenannten Philosophie...

  20. Der flammer en ild

    DEFF Research Database (Denmark)

    Nielsen, Kirsten

    2009-01-01

    Artiklen er et foredrag holdt ved Det Teologiske Fakultets tværfaglige symposium, poesiTEOri, 9. november 2007, under fokusområdets tema 2: Bibel og litteratur. Indledningsvis behandles kort salmer som ritual. Derpå følger en drøftelse af salmer som tekst, herunder forfatterrollen. Som eksempler ...

  1. Kunstens Psykologi og Sansningens Primat

    DEFF Research Database (Denmark)

    Levin, Kasper

    2012-01-01

    . Spørgsmålet er imidlertid om ikke kunstpsykologien udelukker sig selv fra væsentlige indsigter ved på denne måde at behandle kunstværker som traditionelt empiriske eller repræsentationelle genstande. Med udgangspunkt i en analyse af Sigmund Freuds tilgang til kunst vil jeg pege på filosoffen Gilles Deleuze...

  2. Noninvasiv ventilationsbehandling i akutafdelinger

    DEFF Research Database (Denmark)

    Sørensen, Dorthe

    2017-01-01

    også gives som continuous positive airway pressure (CPAP), dvs. en ikke-cyklisk ventilation med et konstant tryk og luftflow, der svarer til en eksspiratorisk modstand, og derfor også er uden egentlig inspiratorisk støtte (2,3). NIV-behandling ved akut respirationssvigt anvendes i dag præhospitalt (4...

  3. Boligmarkedet under inflation

    DEFF Research Database (Denmark)

    Lunde, J.

    Rapportens enkelte kapitler behandler prisdannelsen på boligmarkedet, huslejereguleringen, prisudviklingen på bolig-delmarkederne, fremkomsten af kapital- og debitorgevinster ved besiddelse og belåning af boligejendomme, samt de samfundsøkonomiske årsager til denne prisudvikling og disse gevinstd...

  4. Tuberkulose forårsaget af Mycobacterium africanum

    DEFF Research Database (Denmark)

    Bek, Dorte; Kjeldsen, Marianne Kirstine; Hansen, Nikolaj Friis

    2010-01-01

    Tuberkulose (TB) forårsages af patogene arter fra Mycobacterium tuberculosis komplekset (MTBC) og har en incidens på cirka 7/100.000 i Danmark. På mistanke om TB hos en akut indlagt 40 årig afrikansk mand initieredes anti-TB behandling. Efter 13 timers indlæggelse afgik patienten ved døden. Fra...

  5. Valutasikring og insiderhandel : belyst juridisk, finansielt og regnskabsmæssigt

    DEFF Research Database (Denmark)

    Clausen, Nis Jul; Pedersen, Frank; Thinggaard, Frank

    Valutasikring og insiderhandel behandler de tre vigtige emner fra Danmarkshistoriens første dom om insiderhandel med aktier: finansiel valutasikring, sikring i årsregnskabet og reglerne om insiderhandel. Ved eksempler analyseres, om det virkelig er rigtigt, at oplysninger om tab på kommercielle v...

  6. Biodiversitet i dyrket skov

    DEFF Research Database (Denmark)

    Petersen, Flemming Rune

    . Rapportens anden del er en gennemgang af fire væsentlige indgreb, der påføres skovøkosystemerne ved dyrkningspraksis. Rapportens tredje del behandler særlige driftstyper, der fremmer et stort naturindhold i danske skove, med udgangspunkt i Naturskovsstrategiens beskrivelse af "gamle driftsformer"....

  7. Slutrapport for Implementering af energibesparelser ved benyttelse af  højkvalitets LED belysning PSO 339‐025

    DEFF Research Database (Denmark)

    Dam-Hansen, Carsten; Thorseth, Anders; Poulsen, Peter Behrensdorff

    2010-01-01

    Denne rapport indeholder en beskrivelse af forsknings og udviklingsprojektet ”Implementering af energibesparelser ved benyttelse af højkvalitets LED belysning”. Projektet er udført i et samarbejde imellem DTU Fotonik, Teknologisk Institut, De Danske Kongers Kronologiske Samling (DKKS), Lumodan, Osram, Thermex og DONG Energy under ledelse af Carsten Dam-Hansen, DTU Fotonik. Projektet er finansieret af Dansk Energi under Elforsk’s PSO...... program, indsatsområde 3a. LED belysning. Projektet har projekt nr. PSO 339‐025 og blev startet i februar 2007 og er afsluttet i marts 2010.   I...

  8. Norwegian Wood Innovation

    OpenAIRE

    Larsen, Ingrid Marie Hjellset

    2005-01-01

    Terrengmodellering i 3D er i dag en mye brukt måte å fremstille landskap på. Slike modeller kan man se i utallige dataspill, animasjonsfilmer, og geologiske modeller. Den vanligste måten å fremstille et 3D terreng på er ved bruk av kotekart. Mønsteret i en treplate kan minne mye om slike koter, og ved segmentering av mønsteret kan dette resultatet behandles på samme måte som et ordinært kart. Denne rapporten beskriver hvordan en finerplate kan bli ført fra treplate til trelandskap ved hjelp a...

  9. Trofiske skift og fysiske faktorer i væksten hos Færøske torsk (Gadus morhua) undersøgt ved brug af stabile isotoper

    DEFF Research Database (Denmark)

    Munk-Nielsen, Jens; Christensen, Jens Tang; Grønkjær, P.

    Projektets formål er at forstå variationen i vækst hos torsk (Gadus Morhua) ved brug af otolither (øresten), og sammenhængen med fysiske faktorer, såsom havstrømme, hav temperatur, osv på den Færøske shelf. Dette undersøges ved hjælp af, 1) en otolith vækst kronologi som dækker mere end 60 år (1948...... en mindre amplitude i variationen af ringbredde end direkte vækst målinger. Over hele vækstkronologien ses en negativ udvikling i væksten hos torsk, dog afbrudt af kortere perioder med positiv vækst. De stabile isotop prøver udtages fra hele otolitter fra 5 år gamle torsk. Fra protein delen af...... omgivelser torsken har oplevet, især den omgivende temperatur. Karbon signalet fra den uorganiske del af otolitten vil blive sammenlignet med værdierne i protein delen. De stabile isotop-værdier, samt vækst data vil blive analyseret for at se sammenhængen mellem klimaet og væksten hos torsk. Både lokalt, med...

  10. An adherent nerve root – Classification and exercise therapy in a patient diagnosed with lumbar disc prolapse

    DEFF Research Database (Denmark)

    Melbye, Martin

    2010-01-01

    Patienter med diskusprolaps får oftest besked på, at det ikke skal gøre ondt for at gøre godt, i forbindelse med behandling og genoptræning. Der findes dog en ganske lille gruppe patienter som udvikler en restriktiv tilstand, hvor der dannes adhærencer ved nerveroden, i forbindelse med opheling a...... prolapsen. Tilstanden remodelleres med smertefulde hjemmeøvelser som gradvist progredieres over nogle måneder. En ny case-rapport i Manual Therapy dokumenterer fysioterapidiagnostik, klinisk ræsonnering og behandling af en patient med denne lidelse. Udgivelsesdato: 2010...

  11. Kønsforskelle ved autoimmune sygdomme illustreret ved reumatoid artritis

    DEFF Research Database (Denmark)

    Danneskiold-Samsøe, Bente; Bartels, Else Marie; Dreyer, Lene

    2007-01-01

    Many autoimmune diseases like rheumatoid arthritis (RA) show gender differences. RA is triggered by an interaction between genetic, hormonal, environmental and behavioural factors. 75% of cases are women under the age of 60; lover the age 60 the gender ratio is 1:1. Different genotypes predispose...

  12. Kønsforskelle ved autoimmune sygdomme illustreret ved reumatoid artritis

    DEFF Research Database (Denmark)

    Danneskiold-Samsøe, Bente; Bartels, Else Marie; Dreyer, Lene

    2007-01-01

    for RA. Pregnancy often suppresses RA, as does oral contraception. Lactation, smoking (w), BMI > 30, heavy vibrations and certain dust particles (m) may trigger RA, while the effect of male hormones is uncertain. Future prevention should focus on environment, behavioural factors and genetic profiling....

  13. Neurobiologien ved borderline-personlighedsforstyrrelse

    DEFF Research Database (Denmark)

    Simonsen, Erik; Andersen, Rune

    2012-01-01

    Borderline personality disorder (BPD) is a severe psychiatric disorder characterised by instability of affect regulation, impulse control, interpersonal relationships, and self-image. The aim of this status article is to provide a brief overview of the neurobiological underpinnings of the core...

  14. Fagligt Forum ved en skillevej

    DEFF Research Database (Denmark)

    Bjerg, Claus

    2008-01-01

    Med cvu-bibliotekernes overgang til professionshøjskoler ændres det biblioteksfaglige landskab. Det har Fagligt Forum taget konsekvensen af og nedlægger sig selv i løbet af 2000......Med cvu-bibliotekernes overgang til professionshøjskoler ændres det biblioteksfaglige landskab. Det har Fagligt Forum taget konsekvensen af og nedlægger sig selv i løbet af 2000...

  15. Ekstraintestinale manifestationer ved inflammatorisk tarmsygdom

    DEFF Research Database (Denmark)

    Larsen, Signe; Bendtzen, Klaus; Nielsen, Ole Haagen

    2009-01-01

    dermatological manifestations, while episcleritis, iridocyclitis and uveitis are common ophthalmological complications. Conventional drugs and biologicals have proven effective in the treatment of several of the manifestations, including peripheral arthritis, pyoderma gangraenosum and episcleritis...

  16. Dødsulykker ved bygningsbrande

    DEFF Research Database (Denmark)

    Leth, Peter Mygind; Gregersen, Markil Ebbe Gregers; Sabroe, Svend

    1998-01-01

    %) and accidents with candles (9%). The largest risk groups were chronic alcoholics, handicapped and elderly people. In conclusion, warnings should be issued against smoking in bed and use of loose-fitting clothing while cooking on an open fire. Protective aprons and devices for use while smoking, self...

  17. Bag ved skyerne skinner solen

    DEFF Research Database (Denmark)

    Zobbe, Henrik

    2012-01-01

    På langt sigt skinner solen på erhvervet. De globale udfordringer er store, og landbruget og fødevareindustrien står helt centralt placeret på løsningsdagsordenen......På langt sigt skinner solen på erhvervet. De globale udfordringer er store, og landbruget og fødevareindustrien står helt centralt placeret på løsningsdagsordenen...

  18. Perioperativ vaeskebehandling ved perforeret ulcus

    DEFF Research Database (Denmark)

    Bjerre, Catherine Collin; Holte, Kathrine

    2009-01-01

    INTRODUCTION: Surgery for perforated ulcers is one of the most common emergency surgical procedures. Approximately 400 procedures are performed each year in Denmark and mortality is high, reaching close to 30% at 30 days postoperatively. The importance of perioperative fluid administration during...... fluid administration varied extensively, with fluid balance on the day of surgery ranging from -45 to 8,030 ml (median 2688 ml) and a cumulated fluid balance of 7,2 litres (1,875-14,565 ml) three days postoperatively. Generally, patients had no fluid administered prior to surgery (median 0 ml, applying...... to 41 patients (87%) range 0-4,500 ml).CONCLUSION: Both the preoperative fluid management and the postoperative monitoring of the fluid balance are suboptimal and should be optimized. Individualized (goal-directed) fluid administration aiming at optimizing the oxygen supply to the peripheral tissues...

  19. Ekstraintestinale manifestationer ved inflammatorisk tarmsygdom

    DEFF Research Database (Denmark)

    Larsen, Signe; Bendtzen, Klaus; Nielsen, Ole Haagen

    2009-01-01

    Extraintestinal manifestations are relatively common in chronic inflammatory bowel disease and affect joints, skin, eyes and bile ducts. The most frequent rheumatologic manifestations are peripheral arthritis and axial arthropathies. Erythema nodosum and pyoderma gangraenosum are common...

  20. Nye terapeutiske styringsmuligheder ved leukaemi

    DEFF Research Database (Denmark)

    Jensen, A W; Hokland, P; Jørgensen, H

    1992-01-01

    Investigations on the configuration of immunoglobulin (Ig) and T-cell receptor (TCR) genes have become more and more widespread. Through these methods it is possible to identify malignant clones, which by a transforming event have been blocked in further differentiation but continued to proliferate....... Such clonal expansions can be verified by the Southern Blotting procedure as differences in molecular weight between normal and rearranged DNA fragments. In the lymphatic disorders it is possible to assign the malignant clone to B cell lineage by rearrangement in the immunoglobulin light chain gene, while...... heavy chain and T-cell receptor genes do not show consistency in lineage restriction. In a study on AML patients with solitary expression of the T-cell marker CD7 we have identified a similarity in TCR beta and delta gene configurations, indicating a correlation between etiology and genetic pattern...

  1. Ved vejen – I komplekset

    DEFF Research Database (Denmark)

    Raahauge, Kirsten Marie

    2007-01-01

    tendens til større vinduer, færre vægge og større rum, som er både poly-funktionelle og poly-sociale. Desuden har virtuelle strømme en stor betydning i hverdagen, gennem computer, tv og telefon. Artiklen undersøger relationer mellem materialitet og sociale relationer og argumenterer for, at de to er...

  2. Fordele og ulemper ved forbrugergenetik

    DEFF Research Database (Denmark)

    Christiansen, Camilla Worm; Gerdes, Anne-Marie Axø

    2017-01-01

    Direct-to-consumer genetic tests are sold over the internet to consumers all over the world - including Denmark. No regulation of these tests has been introduced neither in Denmark nor in Europe, even though they have been on the market since 2007. Such tests have several advantages, but indeed...

  3. Nye metoder ved gastrointestinal endoskopi

    DEFF Research Database (Denmark)

    Stigaard, Trine; Meisner, Søren

    2010-01-01

    The development of diagnostic and therapeutic flexible endoscopy is vivid. This article describes some of the most recent diagnostic techniques: Narrow Band Imaging, Fujinon Intelligent Color Enhancement, Autofluorescence Imaging, Optical Coherence Tomography, Confocal Laser Endomicroscopy...

  4. Nye metoder ved gastrointestinal endoskopi

    DEFF Research Database (Denmark)

    Stigaard, Trine; Meisner, Søren

    2010-01-01

    The development of diagnostic and therapeutic flexible endoscopy is vivid. This article describes some of the most recent diagnostic techniques: Narrow Band Imaging, Fujinon Intelligent Color Enhancement, Autofluorescence Imaging, Optical Coherence Tomography, Confocal Laser Endomicroscopy. Liter....... Literature was found through searches on PUBMED and written information from Olympus, Fujinon and Pentax. Which techniques will be used in the future? Will optical biopsy soon be possible? We need more controlled studies....

  5. Psykosociale aspekter ved dissemineret sklerose

    DEFF Research Database (Denmark)

    Stenager, E; Stenager, E N; Knudsen, Lone

    1995-01-01

    Using multiple sclerosis as a model, it is demonstrated how a chronic neurological disorder has psychosocial consequences during the period between onset and diagnosis, at the time of diagnosis, and in the post-diagnostic period. The impact of the disorder on self-esteem, civil status, habitation...

  6. Perioperativ vaeskebehandling ved perforeret ulcus

    DEFF Research Database (Denmark)

    Bjerre, Catherine Collin; Holte, Kathrine

    2009-01-01

    : Retrospective survey of 45 consecutive patients operated for perforated ulcers over a 3-year period between 1 January 2003 and 31 December 2005 in the surgical department of a university hospital. RESULTS: Data that would permit rational fluid therapy are not being collected on a regular basis. Fluid balance...

  7. Genetisk udredning ved infantile spasmer

    DEFF Research Database (Denmark)

    Hansen, Lars Kjærsgaard; Ousager, Lilian Bomme; Møller, Rikke Steensbjerre

    2012-01-01

    Infantile spasms are a symptom of a severe epileptic encephalopathy. It is important to determine the aetiology for a child's disease. When a standard programme for evaluating the aetiology of the infantile spasms is unsuccessful genetic causes should be considered. We suggest array CGH as the fi......Infantile spasms are a symptom of a severe epileptic encephalopathy. It is important to determine the aetiology for a child's disease. When a standard programme for evaluating the aetiology of the infantile spasms is unsuccessful genetic causes should be considered. We suggest array CGH...

  8. Det ved vi om Feedback

    DEFF Research Database (Denmark)

    Christensen, Vibeke; Bærenholdt, Jørgen

    Præsentation af forskningsviden om feedback i forskellige personkonstellationer i undervisningen: Feedback fra lærer til elev, fra elever til lærer, fra elev til elev og elevens eget arbejde med feedback til sig selv. De præsenterede forskningsresultater er udvalgt dels inden for en kognitivistisk...

  9. Biologiske behandlingsmuligheder ved Graves' oftalmopati

    DEFF Research Database (Denmark)

    El Fassi, Daniel; Nielsen, Claus Henrik; Hegedüs, Laszlo

    2008-01-01

    The current medical treatment options for Graves' ophthalmopathy (GO) are unsatisfactory. Recent treatment of GO patients with the B-lymphocyte depleting monoclonal antibody rituximab or with the anti-tumor necrosis factor-alpha agents etanercept and infliximab has shown promising results. We...

  10. Critical Components in Microfluidic Systems for Drug Delivery

    DEFF Research Database (Denmark)

    Bitsch, Lennart

    2006-01-01

    Formålet med denne afhandling har været at evaluere mulighederne for at anvende mikrofluide systemer til medicinsk behandling. Vi har især fokuseret på sikkerhed i reciprokerende pumper, med henblik på en kontinuer insulin behandling, og har identificeret mikroventiler som værende kritiske......-mikroventil. Sammenlignet med systemer der benytter passive ventiler opnår vi et markant højere sikkerhedsniveau med en drejeventil. Teknologien bygger på konstruktion med bløde inkompressible gummimaterialer, og hårde overflader. Grundlæggende studier af dynamisk friktion mellem gummi og en hård overflade viser...... dreje-mikroventiler med gode pakninsgsegenskaber. De overvejende fordele ved nedskalering af mekaniske systemer er mere kompakte, lavenergi-apparater. Vi har vist muligheden for at lave dreje-mikroventiler med lavt energiforbrug og gode pakningsegenskaber ved konstruktion og test af en demonstrator med...

  11. Aktiv kontra passiv forvaltning

    DEFF Research Database (Denmark)

    Bechmann, Ken L.; Pedersen, Lasse Heje

    2017-01-01

    Fordele og ulemper ved aktiv og passiv forvaltning har fået fornyet opmærksomhed blandt andet i forbindelse med den forestående implementering af MiFID II. Som bidrag til denne diskussion indeholder dette nummer af Finans/Invest tre artikler, der behandler aktiv og passiv forvaltning fra...... forskellige vinkler. Denne leder forklarer, hvorfor valget mellem aktiv og passiv forvaltning er mere kompliceret, end hvad man kunne tro ved første øjekast, og konkluderer, at der vil være plads til - og behov for - begge typer forvaltning....

  12. Hepatorenalt syndrom: diagnose, behandling og forebyggelse

    DEFF Research Database (Denmark)

    Egerod Israelsen, Mads; Gluud, Lise Lotte; Bendtsen, Flemming

    2013-01-01

    Cirrhosis, ascites and renal impairment are associated with high morbidity and mortality. The hepatorenal syndrome (HRS) is a type of renal failure that affects patients with cirrhosis and ascites. This paper provides an update on evidence-based interventions in HRS. A number of factors can...

  13. Udvikling af medicinsk behandling mod bipolar lidelse

    DEFF Research Database (Denmark)

    Ellegaard, Pernille Kempel

    2015-01-01

    Selvom Esbjerg ligger i vandkants Danmark, er det den Psykiatriske Forskningsenhed i denne by, der er primus motor for et stort forsøg blandt mennesker, der lider af bipolar lidelse. Forsøget hedder ”NACOS”, og er et medicinsk forsøg til mennesker, der befinder sig i den depressive fase.......Selvom Esbjerg ligger i vandkants Danmark, er det den Psykiatriske Forskningsenhed i denne by, der er primus motor for et stort forsøg blandt mennesker, der lider af bipolar lidelse. Forsøget hedder ”NACOS”, og er et medicinsk forsøg til mennesker, der befinder sig i den depressive fase....

  14. Traditionel og alternativ behandling af sklerosepatienter

    DEFF Research Database (Denmark)

    Stenager, E N; Stenager, Egon; Knudsen, L

    1989-01-01

    The medicine consumption and the employment of alternative treatment were investigated in a material of 117 patients with disseminated sclerosis (DS) considered to be a representative sample of the patients with DS in the County of Funen. This investigation revealed that the preparations most com...... in social classes 4 and 5 and in women. In addition, is was found that there was no difference in social class, sex and age among the patients who employ alternative methods of treatment. The patients themselves have not experienced any effect from alternative treatment....

  15. Eosinofili--patogenese, klassifikation og behandling

    DEFF Research Database (Denmark)

    Andersen, Christen Lykkegaard; Vestergaard, Hanne; Nørgaard, Peter

    2009-01-01

    Eosinophilia represents a complex clinical problem, the management of which is based on case history and clinical examination. Allergy, parasitic infection or inflammation may then be identified or malignancy suspected. In some cases, representing a haematologic disorder, clonality is demonstrate...

  16. Neurointensiv behandling af svaere traumatiske hjerneskader

    DEFF Research Database (Denmark)

    Welling, Karen-Lise Kobberø; Eskesen, Vagn; Romner, Bertil

    2010-01-01

    We present a Danish algorithm for the neurointensive care of patients with severe traumatic brain injury. The primary goal is to avoid cerebral ischaemia and hypoxia and secondarily brain injury. Patient evaluation by a neurosurgeon is mandatory, and decision-making concerning extended cerebral...

  17. Knæartrose - diagnostik og behandling

    DEFF Research Database (Denmark)

    Husted, Henrik; Schrøder, Henrik; Odgaard, Anders

    2014-01-01

    The diagnosis of arthrosis of the knee is based on anamnestic, clinical and radiological findings. Epidemiological Danish data are presented with a diagnostic algorithm. Treatment ranges from initially conservative - although with limited evidence of cost-benefit efficiency - towards surgical int...... intervention. As opposed to dogma suggesting a delay of arthroplasty, early surgical intervention results in improved outcomes. Optimal treatment of co-morbidities and control of haemoglobin before referral to surgery optimizes patient outcome....

  18. Målrettet behandling af lymfoproliferativ sygdom

    DEFF Research Database (Denmark)

    Niemann, Carsten Utoft; Geisler, Christian Hartmann

    2014-01-01

    The development of targeted treatment of chronic lymphocytic leukaemia (CLL) is changing the prognostic outlook for CLL patients. The B-cell antigen receptor pathway is identified as pivotal for CLL pathogenesis and CLL cell proliferation. Inhibition of this pathway by ibrutinib (Bruton's tyrosin...

  19. Behandling med kosmetiske bløddelsfyldere

    DEFF Research Database (Denmark)

    Thyssen, Jacob Pontoppidan; Christensen, Lise H; Zachariae, Claus O C

    2007-01-01

    An increasing number of patients undergo soft-tissue augmentation. The quality depends on the applied filler substance, the compliance of the patient and the physician. Long-term adverse reactions are referred to as nodules or granulomas. Nodules following degradable gels and polyacrylamide...... hydrogel are always caused by bacteria. Nodules following inert, hydrophobic silicone gel and combination gels may emerge years after the injection. They are often caused by a low-grade infection with ensuing enhanced fibrosis and treatment requires a specialist....

  20. MINDFULNESS BEHANDLING AF DANSKE VETERANER - ET PILOTSTUDIE

    DEFF Research Database (Denmark)

    Fjorback, Lone

    2015-01-01

    I foråret 2014 mødtes en gruppe på 12 danske veteraner en gang om ugen i 9 uger for at deltage i programmet Mindfulness Baseret Stress Reduktion (MBSR). Deltagerne havde meldt sig frivilligt, og gruppen var blandet mht. alder, køn, antal udsendelser og diagnoser. Det, de havde til fælles, var...

  1. Moderne behandling af type B-aortadissektion

    DEFF Research Database (Denmark)

    Klitfod, L.; Baekgaard, N.; Just, S.

    2008-01-01

    Rapid classification is essential in the management of aortic dissections, as Type A dissections require surgery, while the optimal treatment of Type B dissections is controversial. Medical treatment with antihypertensive medication and analgesics has so far been the main treatment of uncomplicated...... Type B dissections, while surgery has been reserved for complications and persistent pain in spite of medical treatment. Endovascular techniques are less invasive than open repair and show promising early results Udgivelsesdato: 2008/9/8...

  2. Bilateral akillesseneruptur efter behandling med ciprofloxacin

    DEFF Research Database (Denmark)

    Attarzadeh, Amir Pasha; Ryge, Camilla

    2013-01-01

    We report a case of spontaneous non-traumatic bilateral rupture of the Achilles tendons following ciprofloxacin treatment. A 54-year-old man presented with spontaneous Achilles tendon rupture on the left side, tendinitis and partial tear on the right side following few days of treatment with cipr......We report a case of spontaneous non-traumatic bilateral rupture of the Achilles tendons following ciprofloxacin treatment. A 54-year-old man presented with spontaneous Achilles tendon rupture on the left side, tendinitis and partial tear on the right side following few days of treatment...... with ciprofloxacin 500 mg twice daily and long-term treatment with prednisolon 10 mg once daily. This rare side effect caused by concurrent treatment with steroids and ciprofloxacin should be kept in mind. Any signs of tendinitis following this treatment should arouse the physicians' suspicion towards ciprofloxacin....

  3. Behandling af diabetes mellitus med biologiske laegemidler

    DEFF Research Database (Denmark)

    Larsen, Claus Morten; Mandrup-Poulsen, Thomas

    2008-01-01

    Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps of the patho......Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps...... of the pathogenesis of type 1 and type 2 diabetes which are targeted by biologic therapeutics and reviews the treatment results. Udgivelsesdato: 2008-Jun-9...

  4. Vellykket konservativ behandling efter knivtraume mod hjertet

    DEFF Research Database (Denmark)

    Wærsted, Stian; Schou-Jensen, Katrine; Jensen, Tim

    2012-01-01

    A five year-old girl was admitted to hospital following an accidental stab wound to the chest, inflicted by a knife placed in a dishwasher's cutlery tray. Investigations revealed a traumatic ventricular septum defect of the heart, with a pericardial effusion. Since the patient remained haemodynam......A five year-old girl was admitted to hospital following an accidental stab wound to the chest, inflicted by a knife placed in a dishwasher's cutlery tray. Investigations revealed a traumatic ventricular septum defect of the heart, with a pericardial effusion. Since the patient remained...

  5. Choledocholitiasis. Endoskopisk behandling af 416 konsekutive patienter

    DEFF Research Database (Denmark)

    Pedersen, F M; Brandt, C J; Schaffalitzky de Muckadell, O B

    1998-01-01

    patients who underwent ERC for common bile duct stones between January 1990 and January 1995. The overall success rate of achieving a common bile duct free of stones was 89.0%, and in 94.7% of the patients endoscopic treatment was definitive. The overall complication rate was 9.6% and the 30-day mortality...

  6. Den kardiovaskulaere risikoprofil og antihypertensiv behandling

    DEFF Research Database (Denmark)

    Olsen, Michael Hecht; Sehestedt, Thomas; Prescott, Eva

    2009-01-01

    Estimation of absolute cardiovascular risk is important for choice of primary as well as secondary cardiovascular prevention. In general, physicians are advised to use SCORE in apparently healthy subjects with optimal or normal blood pressure, the ESH risk stratification chart in patients...... with hypertension and either one or even better a combination of the two instruments in apparently healthy subjects with a high normal blood pressure. Udgivelsesdato: 2009-Jun-8...

  7. Den kardiovaskulaere risikoprofil og antihypertensiv behandling

    DEFF Research Database (Denmark)

    Olsen, Michael Hecht; Sehestedt, Thomas; Prescott, Eva

    2009-01-01

    Estimation of absolute cardiovascular risk is important for choice of primary as well as secondary cardiovascular prevention. In general, physicians are advised to use SCORE in apparently healthy subjects with optimal or normal blood pressure, the ESH risk stratification chart in patients...... with hypertension and either one or even better a combination of the two instruments in apparently healthy subjects with a high normal blood pressure. Udgivelsesdato: 2009-Jun...

  8. Biofarmaka til behandling af reumatoid artritis

    DEFF Research Database (Denmark)

    Baslund, Bo; Bendtzen, Klaus

    2008-01-01

    The current status on the use of biopharmaceuticals in the treatment of rheumatoid arthritis is reviewed. Blocking of TNF-alpha, co-stimulation of CD28+ T-cells and depletion of CD20+ B-cells are all effective ways to diminish inflammation and joint damage. However, not all patients react to thes...

  9. Abatacept til behandling af reumatoid artritis

    DEFF Research Database (Denmark)

    Nielsen, Henrik; Hansen, Annette

    2009-01-01

    Abatacept (CTLA4Ig) is a human fusion protein which consists of a cytotoxic lymphocytic-associated type 4 antigen which is bound to the Fc part of the IgG1. Abatacept binds to CD80/CD86 on antigen-presenting cells thus blocking the co-stimulatory signal to the naïve T cells and interfering with a...

  10. Herpes zoster: klinik, diagnostik og behandling

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Rønholt, Finn; Gerstoft, Jan

    2011-01-01

    that early recognition and treatment can reduce acute symptoms, that antiviral therapy and corticosteroids shorten the acute illness period, that opioids and anticonvulsants have effect on acute HZ pain and, finally, that tricyclic antidepressants, opioids and anticonvulsants all have proven efficiency...

  11. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, A.C.; Sørensen, Helle Christina; Sander, Pia

    2010-01-01

    : In total, 94 operating gynaecologists and urologists were identified, 63 responded (71%) of whom 49 (78%) performed UI surgery. UI surgeons were gynaecologists 43 (88%) of these 24 (49%) were urogynecologists (working more than 50% with urogynecology) and five (10%) urologists. Tension-free Vaginal Tape......INTRODUCTION: During the last decade, minimal invasive procedures have been introduced for treatment of urinary incontinence (UI) in women leading to shorter hospitalisation and fewer complications. The aim of this study was to outline clinical practice and attitudes among Danish UI surgeons....... MATERIAL AND METHODS: Surgeons performing UI procedures were identified and mailed a questionnaire in 2007 concerning 2006. Questions included specialisation, number of procedures, type of surgery, complications and attitude towards learning surgery and maintaining a sufficient level of routine. RESULTS...

  12. Diagnostik og behandling af hidrosadenitis suppurativa

    DEFF Research Database (Denmark)

    Ring, Hans Christian; Saunte, Ditte Marie; Riis, Peter Theut

    2017-01-01

    Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease defined by recurrent nodules, tunnels and scarring involving the intertriginous regions. Although patients with HS present a distinct symptomatology with a subsequent impairment of quality of life, an overall diagnostic time...... of seven years has been reported. A better and broader understanding of this disease may potentially reduce the diagnostic delay. This review provides an updated overview of diagnosis, monitoring tools as well as early treatment interventions....

  13. Autoimmun hepatitis. Fremtroedelsesformer, diagnostik og behandling

    DEFF Research Database (Denmark)

    Poulsen, L O; Tage-Jensen, U; Vyberg, M

    1992-01-01

    A retrospective study concerning ten patients with autoimmune hepatitis (AiH), diagnosed during a 2 1/2-year period is presented. The age of the patients ranged from 25 to 82 years and nine of the patients were women. Their symptoms included jaundice, pruritus, fever, anorexia and fatigue during...

  14. Dermatologiske reaktioner hos patienter i antineoplastisk behandling

    DEFF Research Database (Denmark)

    Prasad, Sumangali Chandra; Vestergaard, Hanne; Bygum, Anette

    2014-01-01

    Every year more than 33,000 Danish patients are treated with traditional chemotherapy or targeted therapy against cancer. Cutaneous side effects to these therapies are common and may contribute significantly to the morbidity, but rarely to the mortality of the patients undergoing these treatments....... We present the most classical types of drug rashes associated with antineoplastic therapy. Haematologists, oncologists and dermatologists should be aware of these reactions and early recognition and management is important for providing optimal care....

  15. Ny behandling af kronisk hepatitis B

    DEFF Research Database (Denmark)

    Andersen, Ellen Sloth; Weis, Nina M

    2008-01-01

    Worldwide, 350 million people are infected with chronic hepatitis B. Over the last few years, it has been possible to treat chronic hepatitis B. Treatment very often consists of nucleos(t)ide analogs and in a few cases of pegylated alpha-interferon. In 2007, a new nucleoside analog, Telbivudine...

  16. Kirurgisk behandling af levermetastaser og levercancer

    DEFF Research Database (Denmark)

    Wojdemann, M.; Burcharth, F.; Rokkjaer, M.

    2008-01-01

    Hepatic resection is the golden standard in treatment of tumours from primary liver cancer and colorectal liver metastases, but is appropriate for a variety of other benign and malignant tumours in the liver. The selection of patients and criteria are discussed. Curative liver surgery...

  17. Diagnostik og behandling af neuromyelitis optica

    DEFF Research Database (Denmark)

    Nielsen, Helle Hvilsted; Ravnborg, Mads; Illes, Zsolt

    2014-01-01

    Neuromyelitis optica (NMO) is an inflammatory demyelinating disease characterized by antibodies against aquaporin-4 in up to 80% of the cases and even less in the NMO spectrum disorders, which may be difficult to distinguish from early multiple sclerosis. While immunosuppressive therapy should...

  18. Kirurgisk behandling af midt og lav rectumcancer

    DEFF Research Database (Denmark)

    Bjørn, Maya Xania; Perdawood, Sharaf Karim

    2017-01-01

    Total mesorectal excision (TME) is standard treatment of mid- and low rectal cancer and has evolved with minimally invasive surgery. Laparoscopic TME has proven to be technically challenging, and recent randomized controlled studies fail to prove it oncologically superior to open TME. Robotic......-assisted TME may overcome the technical difficulties and shows comparable oncological results, yet it is associated with significant additional costs. Transanal TME is a promising method which seems to overcome the technical and financial issues of the other techniques, without compromising the short...

  19. Flumazenil til behandling af hepatisk encefalopati

    DEFF Research Database (Denmark)

    Elkjaer, J M; Jensen, T U; Emborg, J

    2000-01-01

    Hepatic encephalopathy (HE) is the neuropsychiatric syndrome that occurs as a complication to liver failure in patients with acute or chronic liver disease. Mental status in this syndrome can range from subtle deficits to coma, with respiratory insufficiency and aspiration to the lungs...

  20. Biologisk behandling af sjaeldne inflammatoriske reumatiske sygdomme

    DEFF Research Database (Denmark)

    Baslund, Bo

    2008-01-01

    The current status of the use of biological medicine in the treatment of adult onset morbus still, Wegeners granulomatosis and systemic lupus erythematosus (SLE) is reviewed. The need for controlled trials is emphasized. Anti-CD20 treatment for SLE patients with kidney involvement and patients...... with Wegeners granulomatosis seems promising. Anti-TNF and IL1 receptor antagonist can control disease activity in most patients with adult morbus still....

  1. Skal alkoholmisbrug overhovedet behandles i almen praksis

    DEFF Research Database (Denmark)

    Barfod, Sverre Malm

    1995-01-01

    Som en del af en international undersøgelse gennemførtes telefon-interviews ud fra et semi-struktureret spørgeskema af 12 tilfældigt udvalgte praktiserende læger samt personlige interviews af seks nøglepersoner i sundhedsvæsenet. Alle de udspurgte praktiserende læger var interesserede i at udføre...

  2. Behandling af Tourettes syndrom med aripiprazol

    DEFF Research Database (Denmark)

    Stenstrøm, Anne Dorte; Sindø, Ingrid

    2008-01-01

    Tourette's syndrome (TS) is a motoric disorder characterised by multiple motor and vocal tics. The treatment for patients with moderate to severe TS includes antipsychotic medication. A case report is described in which a 20 year-old male had taken antipsychotic medication since the age of five......, due to TS. The initial treatment consisted of pimozide and risperidone, both of which had an unsatisfactorily efficacy on tics and side effects in the form of weight gain and sedation. The patient is now treated with aripiprazole and there is a marked reduction of tics and no side effects...

  3. Elektrokemoterapi til behandling af kutane metastaser

    DEFF Research Database (Denmark)

    Falk, Hanne; Matthiessen, Louise Wichmann; Dahlstrøm, Karin

    2015-01-01

    Cutaneous metastases occur in up to 9% of all patients with cancer and may cause discomfort and stigmatization. Electrochemotherapy is a local treatment using electric pulses to permeabilize cell membranes, enabling chemotherapy, such as bleomycin, to enter the cells and increase the cytotoxic...... effect by at least 300-fold. Electrochemotherapy is an efficient, once only treatment for cutaneous metastases with an objective response of 62-99%. Electrochemotherapy can reduce discomfort such as ulceration, oozing, bleeding and pain. Adverse events depend on the size of treatment area, but are very...

  4. Biologisk behandling af psoriasis og psoriasisartritis

    DEFF Research Database (Denmark)

    Kragballe, Knud; Deleuran, Bent

    2008-01-01

    Psoriasis is an immune-mediated inflammatory skin disease which may be associated with psoriatic arthritis. Biological therapy is indicated in patients who do not respond to, or are intolerant to, or have contraindication against traditional therapy. TNFalpha antagonists are used for both skin...

  5. Ipilimumab til behandling af metastaserende melanom

    DEFF Research Database (Denmark)

    Ghasemi, Habib; Schmidt, Henrik; Stolle, Lars Bjørn

    2015-01-01

    Until recently metastatic melanoma was a disease with limited treatment options and a poor prognosis. However, new promising products have been developed. Ipilimumab, a full human anti-cytotoxic T-lymphocyte antigen-4 antibody, has shown improved survival in several clinical trials and is now a p...

  6. Impotens forarsaget af behandling med methotrexat

    DEFF Research Database (Denmark)

    Penninga, Ida Elisabeth Irene; Larsen, H.K.; Andersen, S.E.

    2008-01-01

    impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously Udgivelsesdato: 2008/1/28...

  7. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, Astrid Cecilie; Sørensen, Helle Christina; Sander, Pia

    2010-01-01

    (TVT) was the preferred sling in 2006. A total of 20 (47%) UI surgeons used only TVT, seven (17%) only transobturator slings (TOS) and 15 (36%) both TVT and TOS. Only 11 (24%) performed > 25 TVT per year and 11 (27%) performed > 25 TOS per year. In all, UI surgeons had experience with ten different...

  8. Behandling af peritonsillær absces

    DEFF Research Database (Denmark)

    Anthonsen, Kristian; Trolle, Waldemar

    2012-01-01

    Peritonsillar abscess (PTA) is associated with high morbidity and can cause serious and life-threatening complications. In Denmark, the most commonly isolated bacteria are Fusobacterium necrophorum and Streptococcus pyogenes gr. A. The incidence of PTA in Denmark is 41/100,000/year, the highest...

  9. Vellykket konservativ behandling efter knivtraume mod hjertet

    DEFF Research Database (Denmark)

    Wærsted, Stian; Schou-Jensen, Katrine; Jensen, Tim

    2012-01-01

    A five year-old girl was admitted to hospital following an accidental stab wound to the chest, inflicted by a knife placed in a dishwasher's cutlery tray. Investigations revealed a traumatic ventricular septum defect of the heart, with a pericardial effusion. Since the patient remained haemodynam...

  10. Herpes zoster: klinik, diagnostik og behandling

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Rønholt, Finn; Gerstoft, Jan

    2011-01-01

    Herpes zoster (HZ) is a painful vesicular rash localized to one dermatome. Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show...

  11. Udredning og behandling af morbus Osler

    DEFF Research Database (Denmark)

    Kjeldsen, Anette Drøhse; Andersen, Poul Erik; Tørring, Pernille Mathiesen

    2011-01-01

    Morbus Osler or hereditary haemorrhagic telangiectasia (HHT) is a genetic disorder resulting in development of arteriovenous malformations in the mucosa and in visceral organs. The most common symptom is epistaxis. The disease may, however, cause a variety of other serious manifestations such as ......Morbus Osler or hereditary haemorrhagic telangiectasia (HHT) is a genetic disorder resulting in development of arteriovenous malformations in the mucosa and in visceral organs. The most common symptom is epistaxis. The disease may, however, cause a variety of other serious manifestations...

  12. Farmakologisk behandling af astma under graviditet

    DEFF Research Database (Denmark)

    Akram, Iram; Ulrik, Charlotte Suppli; Johnsen, Claus Rikard

    2016-01-01

    Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least ...

  13. Behandling af ideopatisk hypereosinofilt syndrom med imatinib

    DEFF Research Database (Denmark)

    Sørensen, Anne Louise; Larsen, Herdis

    2008-01-01

    We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded...

  14. Hofteluksation kræver hurtig behandling

    DEFF Research Database (Denmark)

    Demirbas, Bekir

    2012-01-01

    Hip dislocation is an orthopaedic emergency. We report a 79 year-old woman, who was brought to the emergency department after falling on her knee at home. An X-ray confirmed a posterior dislocation of her left hip. A successful prompt reduction was performed in the operation room under general an...... anaesthesia. This uncommon injury represents an orthopaedic emergency and requires immediate reduction to lessen the risk of complications including avascular necrosis of the femoral head....

  15. Hepatorenalt syndrom: diagnose, behandling og forebyggelse

    DEFF Research Database (Denmark)

    Egerod Israelsen, Mads; Gluud, Lise Lotte; Bendtsen, Flemming

    2013-01-01

    Cirrhosis, ascites and renal impairment are associated with high morbidity and mortality. The hepatorenal syndrome (HRS) is a type of renal failure that affects patients with cirrhosis and ascites. This paper provides an update on evidence-based interventions in HRS. A number of factors can...... precipitate HRS. The monitoring, prevention, early detection, and correct treatment of these are essential. Terlipressin combined with albumin is the first-line treatment of type 1 HRS. In type 2 HRS with refractory ascites, liver transplantation and TIPS should be considered....

  16. Medicinsk efterbehandling af brystkraeft. Endokrin behandling

    DEFF Research Database (Denmark)

    Mouridsen, Henning T; Andersen, Jørn

    2007-01-01

    For women with steroid receptor-positive breast cancers, endocrine therapy has proven to be a major component of adjuvant therapy reducing the risk of recurrence and death. The selective estrogen-receptor modulator (SERM) tamoxifen has been well established as safe and effective in the adjuvant...... care of both pre- and postmenopausal women. For premenopausal women, ovarian suppression is an important option to be considered. Additionally, aromatase inhibitors have recently demonstrated further benefits in postmenopausal women. The ideal sequencing of treatment with tamoxifen and/or an aromatase...

  17. Ny behandling af kronisk hepatitis B

    DEFF Research Database (Denmark)

    Andersen, Ellen Sloth; Weis, Nina M; Weis, Nina M

    2008-01-01

    Worldwide, 350 million people are infected with chronic hepatitis B. Over the last few years, it has been possible to treat chronic hepatitis B. Treatment very often consists of nucleos(t)ide analogs and in a few cases of pegylated alpha-interferon. In 2007, a new nucleoside analog, Telbivudine......, was approved to treat chronic hepatitis B. In phase II and ongoing phase III studies, Telbivudine has proven more effective than the nucleoside analog, Lamivudine, which was very often used up until recently. Udgivelsesdato: 2008-Nov-24...

  18. Behandling av akutt hjerteinfarkt : Trombolyse versus PCI

    OpenAIRE

    Grut, Harald

    2007-01-01

    ABSTRACT Title: Treatment of acute myocardial infarction: Trombolysis versus PCI Background: Acute myocardial infarction is a frequent cause of mortality and morbidity in Norway and other Western countries. The main objective was to examine which treatment would give the best result in the case of an acute myocardial infarction, trombolysis or PCI, considering both mortality and morbidity. I also wanted to compare PCI to facilitated PCI and prehospital trombolysis. Methods: This ...

  19. Behandl dig selv med honning"

    DEFF Research Database (Denmark)

    Mejrup, Kristian; Bjerring-Nielsen, Mattias

    2015-01-01

    Abstract: This article has a twofold purpose: to investigate the symbolic richness and abundant sweetness of honey and to employ ‘honey treatment’ as a strategy for reading the honeycombapocalypse comprised in the Jewish legend of Joseph and Aseneth. This text tells of Aseneth’s encounter with a ...... entirely perturbed and paralysed. In fact, her free speech and wits remain as if protected by a honeysweetened agency. The article emphasizes the necessity of a ‘conversion’ by the reader enabling him to grasp the sublime potential of the aesthetics of sweetness....

  20. Behandling af svaer hypovolaemi med hypertont saltvand

    DEFF Research Database (Denmark)

    Rask, H; Nielsen, S L; Crawford, M E

    1996-01-01

    of hypovolaemia HS instantaneously expands plasma volume and improves central haemodynamics through increased filling pressures and direct myocardial stimulation. HS, as compared to isotonic fluids, causes precapillary vasodilation, reduction of cell oedema and decreased haematocrit and hence improves regional...... and capillary perfusion. Furthermore HS-infusion has been shown to attenuate reperfusion injury and restore cell function in cells damaged during hypovolaemic shock. Animal experiments as well as clinical studies on the use of HS are reviewed. A short description of the pathophysiology of acute hypovolaemic...

  1. Operativ behandling af thoracic outlet syndrome

    DEFF Research Database (Denmark)

    Birkeland, Peter; Stiasny, Jerzy

    2012-01-01

    of the brachial plexus. At surgery, we found and severed a fibrous band that compressed the inferior trunk. Postoperatively, the pain subsided and fine hand movements improved. One patient had no cervical rib, however, in the two other cases we found rudimentary cervical ribs. Magnetic resonance imaging......We present three cases with longstanding true neurogenic thoracic outlet syndrome. All patients had aching pain in the shoulder, arm and ulnar border of the hand. On examination, we found atrophy of the hand muscles. Electromyography revealed signs of compromised function of the inferior trunk...

  2. NY KANDIDATUDDANNELSE I LYSDESIGN

    DEFF Research Database (Denmark)

    Hansen, Ellen Kathrine; Mullins, Michael

    2013-01-01

    En kandidatuddannelse på højt internationalt niveau i lysdesign har været drøftet og ønsket gennem mange år blandt branchens aftagere. Der er en bred enighed om, at der i Danmark er behov for en tværfaglig uddannelse i lysdesign. Aalborg Universitet, Institut for Arkitektur og Medieteknologi har ...... Denmark, ved positiv behandling forventes, at de første stude- rende starter i september 2014....

  3. Plast og Brand

    DEFF Research Database (Denmark)

    Jensen, Jens Kristian Jehrbo

    Dette skrift behandler emnet: plast og brand set i relation til anvendelserne i byggeriet. Den udstrakte brug af plastmaterialer gør det nødvendigt at være opmærksom på forhold vedrørende termisk nedbrydning af brand. En analyse af plastmaterialer kan foretages ved hjælp af ret simple prøver , og...

  4. Predicting effects and risk of relapse into depression: The Danish ECT/MRI project

    DEFF Research Database (Denmark)

    Gbyl, Krzysztof; Rosenberg, Raben; Larsson, Henrik Bo Wiberg

    Formål: Vi ønsker at undersøge hjernen hos patienter med svær depression før og efter elektrokonvulsiv terapi (ECT), samt ved en kontrol efter 6 måneder med det formål at: 1. undersøge hjernevævet så en evt. skadelig effekt af ECT-behandling kan udelukkes 2. belyse mekanismerne bag ECT for at fin...

  5. Tilbagebetaling af sociale ydelser

    DEFF Research Database (Denmark)

    Hielmcrone, Nina Elisabeth von

    konstateres, at der foreligger fejl og forsømmelser hos både modtager og myndighed. Dermed stilles der også spørgsmålstegn ved de såkaldt "objektive" tilbagebetalingsbestemmelser som f.x. i boligstøttelovens § 47 stk. 1 og 2.       Bogen behandler desuden de mange og vanskelige fortolkningsproblemer, der...... knytter sig til anvendelsen af tilbagebetalingsbestemmelserne i de sociale love....

  6. Praksis som læringsmetode i ingeniørutdanningen – erfaringer fra ingeniørstudiet i undervannsteknologi - drift og vedlikehold ved Høgskolen i Bergen (HiB

    Directory of Open Access Journals (Sweden)

    Laila Linde Lossius

    2014-05-01

    Full Text Available Norsk ingeniørutdanning har blitt kritisert for å være for teoretisk. Næringslivets hovedorganisasjon (NHO m.fl. startet derfor prosjektet «Lærlingeordning i høyere utdannelse». Høgskolen i Bergen dro nytte av erfaringene derfra, og i 2007 – da bachelorstudiet i undervannsteknologi startet – var forutsetningen at studiet skulle ha stor praksisandel og mye kontakt med lokalt næringsliv. Studiet har blitt Norges mest etterspurte treårige ingeniørstudium. Frafallet har vært lavere enn ved andre ingeniørstudier. Studiet har inneholdt flere praksisformer, hvorav bacheloroppgave i bedrift, ingeniørpraksis og verkstedpraksis ble regnet som de mest utbytterike ut fra svar i spørreundersøkelsene. 72 % av studentene anså praksis som en viktig årsak til at de søkte. Faglig interesse og utsikt til gode jobber var dog viktigst. 71 % av studentene opplevde at praksis underveis ville gjøre dem til bedre ingeniører, mens 55 % mente det hadde innvirkning på at de fullførte studiet. Praksisbedriftene har tjent ved bedret rekruttering, de største opptil 0,7 ansatt per praksisplass. Praksisorganisering er krevende, og kvalitetssikring og oppfølging er viktig for å få et godt resultat. Bedriftsnettverk er gode støttespillere, men skolen må også avsette nok ressurser til arbeidet. Siden skader kan skje i industrien, må forsikringsordninger av studenter i praksis settes på den politiske agendaen slik at regelverket kan endres. Summary Norwegian engineering studies has been criticized of being too theoretical. Bergen University College used experiences from the project “Apprenticeship in higher education” when starting the engineering program in Subsea technology in 2007. Much practice and contact with local industry was requested. The program has become popular and dropout is lower than in comparable programs. Student surveys revealed the most rewarding practice to be a company-based Bachelor thesis, engineer internships and

  7. Effect of intensive multifactorial treatment compared with routine care on aortic stiffness and central blood pressure among individuals with screen-detected type 2 diabetes

    DEFF Research Database (Denmark)

    Johansen, Nanna Borup; Charles, Morten; Vistisen, Dorte

    2012-01-01

    Baggrund: Interventionsstudier med kardiovaskulære endepunkter kræver meget store studie populationer og/eller en lang opfølgningstid. Intermediære endepunkter som ligger i den kausale gangsti mod klinisk relevante endpunkter er derfor brugbare redskaber til at vurdere effekten af behandling i...... studie som mangler tilstrækkelig kardiovaskulære tilfælde. Aorta stivhed er et anerkendt intermediært endemål i kliniske studier. I ADDITION Danmark studiet fik en del af deltagerne ved 6 års opfølgningsundersøgelsen undersøgt aortisk stivhed, målt ved karotid-femoral pulsbølge hastighed. Vi undersøgte...... herigennem effekten af intensiv multifaktoriel behandling sammenlignet med rutine behandling i almen praksis. Resultater: Patienterne in intensiv gruppen havde en 0,51 m/s (95%CI: -0,96; -0,05; p-værdi:0.03) sammenlignet med rutine behandlingsgruppen. Ekstrapolering af disse resultater på basis af en meta...

  8. Blodtryksnedsaettelse kan forvaerre symptomerne ved akut apopleksi

    DEFF Research Database (Denmark)

    Garde, E; Jørgensen, H S; Olsen, T S

    1995-01-01

    Patients with acute stroke often present with high blood pressure (BP) on hospital admission. Because hypertension is a risk factor for stroke, and because severe BP elevation may increase oedema and the risk of haemorrhage, acute antihypertensive therapy might seem reasonable. On the other hand...

  9. Rickettsiose som differentialdiagnostisk overvejelse ved rejserelateret feber

    DEFF Research Database (Denmark)

    Kibsgaard, Line

    2012-01-01

    , rickettsiosis should be considered in the returned traveller with fever, especially when malaria, dengue fever and typhoid fever have been excluded. There is a possibility that doxycycline may have a prophylactic effect on rickettsiosis, but this thesis is only imaginary and needs further investigation.......Rickettsial diseases are increasingly reported in international travellers. Prospective studies have shown that 2-4 % of travellers returning with fever have a rickettsiosis. We discuss epidemiology, clinical findings, diagnostics, treatment and prevention of rickettsiosis. In conclusion...

  10. Katetervejledt trombolyse ved perifer arteriel okklusion

    DEFF Research Database (Denmark)

    Lindholt, J S; Holt, G; Sandermann, J

    2001-01-01

    ), occlusions seems beneficial but long-term results are lacking and recurrences are common. Exclusion of preoperative thrombolysis in late and longer lasting occlusions (> 14 days) is debatable, because of a potential thrombolysis-caused improved run-off. Individual case selection is still needed, because...

  11. Ekstrapulmonale komplikationer ved mycoplasma pneumoniae-infektioner

    DEFF Research Database (Denmark)

    Bjørn, Anne-Mette Bay; Lebech, Anne-Mette K

    2002-01-01

    Mycoplasma pneumoniae is a common cause of atypical pneumonia in children and young adults. The infection is generally mild and only a very few patients are admitted to hospital. However, extrapulmonary complications are well recognised--mostly as manifestations from the central nervous system (CNS)....

  12. Antibiotikavalg ved purulent meningitis uden bakteriologisk diagnose

    DEFF Research Database (Denmark)

    Krarup, H B

    1989-01-01

    A case of meningitis in a 16 month old boy caused by Hemophilus influenzae resistant to ampicillin is presented. The question is raised whether a third generation cephalosporin such as cefotaxime should be the drug of choice in the treatment of bacterial meningitis with unknown etiology...

  13. Biofilm ved kronisk rhinosinuitis og cystisk fibrose

    DEFF Research Database (Denmark)

    Fisker, Jacob; Buchwald, Christian von; Johansen, Helle Krogh

    2011-01-01

    Microbial biofilms are known to cause persistent foreign-body infections and have recently been acknowledged as involved in more than 65% of all human infections. Microbial biofilms have been detected in chronic rhinosinusitis, and chronic rhinosinusitis is mandatory in patients with cystic...

  14. Helbredsrisici ved eksponering for styren i glasfiberplastindustrien

    DEFF Research Database (Denmark)

    Kolstad, Henrik Albert; Ebbehøj, Nielse; Bonde, Jens Peter

    2012-01-01

    system effects with for instance reduced psychological performance, colour discrimination and hearing level following long-term styrene exposure above 10 ppm. There is moderate evidence of a causal association with cancer, but data are not sufficient to allow us to pinpoint specific cancers at risk...

  15. Finnålsaspirationscytologi ved mammografiscreening

    DEFF Research Database (Denmark)

    Engvad, Birte; Laenkholm, Anne-Vibeke; Schwartz, Walter

    2009-01-01

    INTRODUCTION: In the year 2000 a quality assurance programme for the preoperative breast diagnostics was introduced in Denmark. The programme was based on the "European guidelines for quality assurance in breast cancer screening and diagnosis" where - among other measures - five cytological......-choice treatment. MATERIAL AND METHODS: 767 women had FNAC performed from a total of 783 lesions at the Mammography Clinic, University Hospital Odense. All FNACs were compared with the final histology diagnosis. Nine statistical parameters were calculated according to the European guidelines. RESULTS: A total...... of 66% of the 783 FNACs had a malignant cytology diagnosis, which in 99% of the cases turned out to be the correct diagnosis. Four lesions were false positives all of which represented benign proliferative breast diseases. The surgical procedures in these cases were either excisional biopsy...

  16. Beta-2-mikroglobulin ved medicinske sygdomme

    DEFF Research Database (Denmark)

    Hansen, P B; Olsen, Niels Vidiendal

    1989-01-01

    Beta-2-microglobulin (beta 2M) is a low-molecular protein which is filtered freely over the glomeruli. Under normal circumstances, more than 99.9% is resorbed in the proximal tubuli of the kidneys and is metabolized there. In renal disease with damage to this segment of the nephron, eg acute tubulo...

  17. Optisk og videoassisteret laryngoskopi ved vanskelige luftveje

    DEFF Research Database (Denmark)

    Johansen, Mathias; Afshari, Arash; Kristensen, Billy B

    2009-01-01

    over direct laryngoscopy including a better view of the larynx, reduced tracheal intubation time and educational value. We present an overview of the currently most used optical and video-assisted laryngoscopes with a special focus on the McGrath Series 5 videolaryngoscope. Udgivelsesdato: 2009-Nov-23......Airway management is one of the greatest anaesthesiologic challenges. Direct laryngoscopy using a standard McIntosh laryngoscope has been the predominant intubation choice for many years. Videolaryngoscopy is becoming a widely accepted airway management technique owing to its potential advantages...

  18. Optisk og videoassisteret laryngoskopi ved vanskelige luftveje

    DEFF Research Database (Denmark)

    Johansen, Mathias; Afshari, Arash; Kristensen, Billy B

    2009-01-01

    Airway management is one of the greatest anaesthesiologic challenges. Direct laryngoscopy using a standard McIntosh laryngoscope has been the predominant intubation choice for many years. Videolaryngoscopy is becoming a widely accepted airway management technique owing to its potential advantages...... over direct laryngoscopy including a better view of the larynx, reduced tracheal intubation time and educational value. We present an overview of the currently most used optical and video-assisted laryngoscopes with a special focus on the McGrath Series 5 videolaryngoscope.......Airway management is one of the greatest anaesthesiologic challenges. Direct laryngoscopy using a standard McIntosh laryngoscope has been the predominant intubation choice for many years. Videolaryngoscopy is becoming a widely accepted airway management technique owing to its potential advantages...

  19. Hastigt progredierende synstab ved idiopatisk intrakraniel hypertension

    DEFF Research Database (Denmark)

    Skau, Maren; Jensen, Rigmor; Milea, Dan

    2009-01-01

    Idiopathic intracranial hypertension (IIH) is a condition of increased intracranial pressure of unknown aetiology. Slowly progressing visual defects secondary to papilloedema are well-known complications. Rapidly progressing visual loss is rare. A case of acute and rapidly progressing visual loss...... in idiopathic intracranial hypertension is presented. Rapid recognition and treatment of IIH is important, and may occasionally prompt acute surgical treatment....

  20. Hastigt progredierende synstab ved idiopatisk intrakraniel hypertension

    DEFF Research Database (Denmark)

    Skau, Maren; Jensen, Rigmor; Milea, Dan

    2009-01-01

    Idiopathic intracranial hypertension (IIH) is a condition of increased intracranial pressure of unknown aetiology. Slowly progressing visual defects secondary to papilloedema are well-known complications. Rapidly progressing visual loss is rare. A case of acute and rapidly progressing visual loss...... in idiopathic intracranial hypertension is presented. Rapid recognition and treatment of IIH is important, and may occasionally prompt acute surgical treatment. Udgivelsesdato: 2009-Jan...

  1. Forskning ved regionale hospitalsenheder i Vestdanmark

    DEFF Research Database (Denmark)

    Nielsen, Gunnar Lauge; Petersen, Lars Jelstrup; Hornung, Nete

    2009-01-01

    INTRODUCTION: According to recently passed Danish legislation, all Danish hospitals are obliged to take part in scientific research. As data on financial support for research activities are lacking, we assessed the resources allocated to research from the budget of the central hospital management...... on research activities. CONCLUSION: In the majority of regional hospitals in Western Denmark, less than 0.3% of the total budget administered by the central hospital management was allocated specifically for research. These figures, however, may not be accurate as individual departments may allocate...

  2. Osmotisk demyeliniseringssyndrom ved Addisonkrise og svaer hyponatriaemi

    DEFF Research Database (Denmark)

    Andersen, Signe Elisabeth Bødker; Stausbøl-Grøn, Brian; Rasmussen, Torsten Bloch

    2008-01-01

    Acute adrenal insufficiency is a life threatening disease with dehydration, hypotension, cerebral dysfunction and gastrointestinal symptoms accompanied by low plasma sodium and high plasma potassium. Osmotic demyelination syndrome (ODS) can occur rarely following correction of plasma sodium. We d...

  3. Helbredsrisici ved eksponering for styren i glasfiberplastindustrien

    DEFF Research Database (Denmark)

    Kolstad, Henrik Albert; Ebbehøj, Nielse; Bonde, Jens Peter

    2012-01-01

    or relevant exposure levels. We recommend reconsideration of the current Danish threshold limit value of 25 ppm, biological monitoring of styrene exposed workers, and epidemiological analyses of styrene exposure levels and long-term health effects among employees of the Danish reinforced plastics industry....

  4. "Jeg har altid haft nemt ved tingene"

    DEFF Research Database (Denmark)

    Rasmussen, Annette; Rasmussen, Palle

    Rapporten analyserer talentundervisningen på 8. og 9. klassetrin i Hjørring Kommune i skoleåret 2006-2007. Der var tale om ekstraundervisning uden for normal skoletid. Det faglige indhold lå inden for fysik, kemi, biologi, matematik og engelsk, og både folkeskolelærere og gymnasielærere medvirked...

  5. Risiko for affektiv lidelse ved multipel sklerose

    DEFF Research Database (Denmark)

    Stenager, Elsebeth Nylev; Stage, Kurt Bjerregaard; Stenager, Egon

    2011-01-01

    of the relevant literature. The study recommends assessment of all MS patients for depression. Treatment of depression with serotonin reuptake inhibitors and/or cognitive behavioural therapy is recommended, depending on the severity of the illness. Caution is recommended in patients receiving beta interferon...

  6. Osteoporose er hyppig ved Parkinsons sygdom

    DEFF Research Database (Denmark)

    Ezzatian-Ahar, Shabnam; Schwarz, Peter; Pedersen, Stephen Wørlich

    2015-01-01

    patients have higher risk of developing osteoporosis and hip fracture compared to those without PD because of lower bone mineral density (BMD) and lack of vitamin D. Prevention of fracture in PD patients should include fall-risk screening, BMD measurements by DXA scan and screening for risk factors......The risk of developing osteoporosis, as well as Parkinson's disease (PD) is increased with increasing age, resulting in increased risk of fracture, particularly hip fractures. Each one of these two conditions can be debilitating and affect the individual patient's quality of life negatively. PD...

  7. Fund af lymfeknuder ved kolorektal cancer

    DEFF Research Database (Denmark)

    Schmidt, Mads Bo; Engel, Ulla; Mogensen, Anne Mellon

    2009-01-01

    that may influence the detection of LNs, including patient- as well as surgeon- and pathologist-related issues. The pathologist-related variable most probably shapes the yield the most. Introduction of guidelines focusing on the most appropriate technique may secure better and more consistent results...

  8. Diagnosticering af choledochussten ved symptomgivende galdestenssygdom

    DEFF Research Database (Denmark)

    Kristiansen, V B; Rosenberg, J; Kehlet, H

    2000-01-01

    as such in the future. Patients with cholangitis, jaundice and common bile duct stones visualised by transabdominal ultrasound have a high risk of common bile duct stones, and these patients can therefore undergo endoscopic retrograde cholangiography directly. Other patients should have a magnetic resonance...

  9. Traditionsbestemt sygepleje ved næseblod

    DEFF Research Database (Denmark)

    Nielsen, Annette Lønsmann; Kristensen, Vibeke G.; Boll, Birgitte

    2005-01-01

    A nation-wide poll was carried out in 2003 of ear, nose and throat departments in Denmark, with a view to reviewing the treatment of patients admitted with nosebleeds. In 2001, 1836 patients were admitted to hospital in Denmark with nosebleeds. The majority of admissions are to ear, nose and throat...... departments, although one also comes across patients with no speeds in other clinical departments and in the primary health service. The purpose of the article is to pass on knowledge about nursing to patients who suffer from nosebleeds. It is evident that nursing in Denmark varies considerably as regards...... diet and the extent to which patients are mobilised. Other aspects of nursing harmonise substantially. Applicable to all fields of nursing pertaining to patients with nosebleeds is the fact that evidence is wanting. Finding recent literature on the subject has been difficult. The assembled expertise...

  10. Radiofrekvensablation reducerer risikoen ved dysplastisk Barretts oesophagus

    DEFF Research Database (Denmark)

    Achiam, Michael; Holm, Jakob; Svendsen, Lars Bo

    2014-01-01

    Barrett's esophagus (BE) with dysplasia is generally accepted as the precursor to oesophageal cancer. Thus, methods to eradicate BE and dysplasia have been evaluated. Recently, radiofrequency ablation (RFA) has shown promising results with few adverse effects. The studies concerning RFA are...

  11. Radiofrekvensablation reducerer risikoen ved dysplastisk Barrett oesophagus

    DEFF Research Database (Denmark)

    Achiam, Michael; Holm, Jakob; Svendsen, Lars Bo

    2014-01-01

    Barrett's esophagus (BE) with dysplasia is generally accepted as the precursor to oesophageal cancer. Thus, methods to eradicate BE and dysplasia have been evaluated. Recently, radiofrequency ablation (RFA) has shown promising results with few adverse effects. The studies concerning RFA are...

  12. Om sprog og kultur ved jobsamtaler

    DEFF Research Database (Denmark)

    Kirilova, Marta

    2017-01-01

    -made job interviews, and later on through workplace mentoring, language courses and professional upgrades. At first sight, the ‘IO-stillinger’ job project was an example of an affirmative action towards the integration of immigrants in the workplace. In practice, however, the recruitment process...

  13. Regulering af cytokindannelse ved inflammatoriske tarmsygdomme

    DEFF Research Database (Denmark)

    Ferrero-Miliani, Laura; Seidelin, Jakob Benecidt; Nielsen, Ole Haagen

    2006-01-01

    Interleukin-1beta (IL-1beta) is a pivotal mediator in the inflammatory immune response that is characteristic of a number of chronic disorders. The etiology and pathophysiology of inflammatory bowel disease (IBD) have for many years been an enigma. The recent identification of the inflammasome, a......, a multiprotein complex responsible for interleukin-1beta converting enzyme (ICE, caspase-1) activation, has generated new possibilities for the elucidation of the etiology and pathophysiology of IBD and as a consequence also for the identification of new treatment targets....

  14. Tidsforbrug ved monitorering af postoperativ oxygenstatus

    DEFF Research Database (Denmark)

    Lavrsen, M J; Tuxøe, J I; Koch, J S

    1997-01-01

    The purpose of the study was to compare use of time with pulse oximetry versus arterial blood gas measurement on the general surgical ward. Eighty patients who had just had major orthopaedic or abdominal surgery were included in the study at two hospitals in Copenhagen. Success rate for pulse...... were delayed median 58 minutes compared with 32 minutes at Sundby Hospital (p porter. No patient had hypercapnia or acid-base disturbances....... We recommend that all general surgical wards should have a portable pulse oximeter for monitoring arterial oxygenation after major surgery....

  15. Kognitive forstyrrelser ved svaer traumatisk hjerneskade

    DEFF Research Database (Denmark)

    Engelmann, Christina Malling; Siert, Lars

    2007-01-01

    Traumatic brain injury (TBI) very often has extensive effects of cognitive character such as changes in recognition, thought, memory, language and perception. The purpose of this paper is to give a short status of cognitive impairment after severe traumatic brain injury and to illustrate that cog...

  16. Leverfibrose kan vurderes ved ikkeinvasiv ultralydelastografi

    DEFF Research Database (Denmark)

    Thielsen, Peter; Wilkens, Rune; Rafaelsen, Søren Rafael

    2015-01-01

    Diagnosis and assessment of liver fibrosis is of great importance for initiating treatment and starting hepatocellular carcinoma surveillance in patients with established cirrhosis. Liver biopsy is still considered the gold standard for liver fibrosis staging, however; it is far from perfect. Non...

  17. Urinretention ved postoperativ smertebehandling med epidurale opioider

    DEFF Research Database (Denmark)

    Hansen, B J; Rosenberg, J; Andersen, J T

    1990-01-01

    . Inhibition of per- and postoperatively increased sympathetic activity may possibly prevent PU. Carbacholine is not effective in the treatment of postoperative retention of urine. In animal experimental studies, kappa-receptor agonists have an analgesic effect without urodynamic side-effects but no clinical...

  18. Molekylaer patogenese ved monogen og polygen fedme

    DEFF Research Database (Denmark)

    Larsen, Philip J; Echwald, Søren Morgenthaler; Sørensen, Thorkild I A

    2006-01-01

    During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us c...... closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns....

  19. Fremstilling af dias ved hjaelp af mikrodatamaten

    DEFF Research Database (Denmark)

    Moesgaard, F A; Schmidt, A E; Hammer, J H

    1990-01-01

    For production of dias for presentation of scientific data, a personal computer, a dias programme and a camera are necessary. A microdatamat with a 80286 precessor, 20 MB hard disc and an EGA colour screen are the minimum configurations which can be recommended. A hard disc between 40 and 85 MB a...... with Harvard Graphics.(ABSTRACT TRUNCATED AT 250 WORDS)...

  20. Neuroradiologiske forandringer ved undertrykkelse af tics

    DEFF Research Database (Denmark)

    Larsen, Sara Bohn; Sørensen, Camilla Birgitte; Skov, Liselotte

    2017-01-01

    Neuroradiological changes by suppression of tics Tourette’s syndrome is characterized by involuntary tics. First choice of treatment has been pharmacological, but recently, behavioural therapy teaching patients to suppress their tics has been introduced. Neuroimaging studies have shown an increased...... activity in the prefrontal cortex, temporal lobes and caudate nucleus, and a decreased activity in globus pallidus and putamen during inhibition of tics. The activity in the frontal lobes changes with age, probably caused by a lack of compensatory hypertrophy. In order to fully understand the mechanism...

  1. Svaer hyperkaliaemi ved gastroenteritis hos kolektomeret patient

    DEFF Research Database (Denmark)

    Hansen, Lasse Bremholm; Winkel, Rasmus; Hansen, Erik Feldager

    2010-01-01

    Severe hyperkalemia is a life-threatening condition that causes primarily cardiac and muscular dysfunction with potentially fatal consequences. This case report describes a case of severe hyperkalemia (9,1 mmol/l) caused by acute prerenal failure due to dehydration. The severe dehydration was cau...... was caused by a combination of reduced fluid intake due to gastroenteritis and a hampered capacity for intestinal fluid absorption, due to previous colectomy. The patient developed classic signs of hyperkalemia with electrocardiogram changes and muscular dysfunction....

  2. Definition, klassifikation og epidemiologi ved whiplash

    DEFF Research Database (Denmark)

    Jensen, Troels Staehelin; Kasch, Helge; Bach, Flemming Winther

    2010-01-01

    A whiplash trauma is caused by an acceleration-deceleration force transferring its energy to the cervical spine. Whiplash-associated disorder (WAD) refers to the symptoms that develop after a whiplash injury. The prognosis is favorable with recovery in over 90% of the injured subjects...

  3. Arbejdsmiljø ved udbud af busdrift

    DEFF Research Database (Denmark)

    Wiegmann, Inger-Marie; Mathiesen, Karin; Hasle, Peter

    En undersøgelse af sammenhængen mellem arbejdsmiljø og udbud af busdrift i tre trafikselskabet. Resultaterne peger på at arbejdsmiljøet går fra udelukkende til at være et anliggende mellem arbejdsgiver og arbejdstager til et trepartsforhold hvor også udbyder (trafikselskabet) får et ansvar og har...

  4. Rapport om digitale oplysninger ved Aalborg Universitet

    DEFF Research Database (Denmark)

    Bønsing, Sten

    Rapport til Aalborg Universitets ledelse vedr. brug af digitale oplysninger i forbindelse med e-mailing, databaser, hjemmesider mv.......Rapport til Aalborg Universitets ledelse vedr. brug af digitale oplysninger i forbindelse med e-mailing, databaser, hjemmesider mv....

  5. Udfordringer og strategier ved produktion af biodiesel

    DEFF Research Database (Denmark)

    Madsen, Anders Theilgaard; Riisager, Anders; Fehrmann, Rasmus

    2009-01-01

    I takt med at verdens olieressourcer forbruges, øges fokus på fornybare brændsler, der ikke medfører stigning i CO2-udledningen. Der er især opmærksomhed på biobrændstoffer som mulige alternativer eller additiver til petrobrændstof...

  6. Lav risiko for komplikationer ved screeningskoloskopi

    DEFF Research Database (Denmark)

    Thamsborg, Lise Laurberg Holst; Andersen, Ole; Fischer, Thea Kølsen

    2013-01-01

    In 2014, screening for colorectal cancer is scheduled to be introduced in Denmark using immunochemical test for blood in faeces (iFOBT). Positive tests are followed by colonoscopy. This review evaluates the risk of perforation, haemorrhage and death associated with screening colonoscopy based...... on selected recent publications. The risk of perforation and haemorrhage was reported to be 0.01% and 0.02% respectively. No deaths were reported. The studies vary in design and demographic characteristics why the findings are relevant regarding the planned national screening programme....

  7. Genetik og stressende livsbegivenheder interagerer ved depression

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel; Bukh, Jens Otto Drachmann

    2013-01-01

    The aim of the present review was to present clinical aspects of recent research in genes, the experience of stressful life events and depression. 60-70% experience a moderate to severe stressful life event half a year prior to the first onset of depression, whereas later depressive episodes...... to a lesser extent are preceded by stressful life events. Clinical features do not differ between depressions with or without prior stressful life events. Certain genetic variations in the serotonin receptor system seem to increase the risk of developing depression in relation to experiencing stressful life...

  8. Generaliserede kramper som debutsymptom ved Gitelmans syndrom

    DEFF Research Database (Denmark)

    Hvelplund, Carolina; Jeppesen, Eva Mosfeldt; Mortensen, Henrik B

    2009-01-01

    Gitelman's syndrome is a rare autosomal recessive syndrome presenting with hypocalciuria, hypomagnesiemia and hypokalemic metabolic alkalosis. This case reports a patient admitted with generalized seizures with the above-mentioned biochemical abnormalities, thus representing a rare onset of Gitel...

  9. Smerte og smertemestring ved juvenil idiopatisk artritis

    DEFF Research Database (Denmark)

    Herlin, Troels; Thastum, Mikael

    2008-01-01

    Pain is one of the primary symptoms of juvenile idiopathic arthritis (JIA). JIA patients have reduced pain tolerance and pain threshold compared to healthy controls. In children with JIA the greater use of coping strategies such as problem-solving, positive self-statements and distraction consist...

  10. Biologisk terapi ved juvenil idiopatisk artritis

    DEFF Research Database (Denmark)

    Herlin, Troels

    2008-01-01

    In recent years the treatment of juvenile idiopathic arthritis (JIA) has undergone marked changes. There is substantial evidence that inhibitors of tumor necrosis factor alpha (TNFalpha) like etanercept, infliximab and adalimumab show significant efficacy when standard therapy fails, and long-ter...

  11. Helbredsrisici ved eksponering for styren i glasfiberplastindustrien

    DEFF Research Database (Denmark)

    Kolstad, Henrik Albert; Ebbehøj, Nielse; Bonde, Jens Peter

    2012-01-01

    or relevant exposure levels. We recommend reconsideration of the current Danish threshold limit value of 25 ppm, biological monitoring of styrene exposed workers, and epidemiological analyses of styrene exposure levels and long-term health effects among employees of the Danish reinforced plastics industry.......This is a summary of the health risks of occupational styrene exposure based on recent reviews. We conclude about the exposure levels that there is strong evidence that styrene causes acute irritation of eyes and respiratory tract above 25 ppm, genotoxic effects above 10 ppm, and persistent nervous...... system effects with for instance reduced psychological performance, colour discrimination and hearing level following long-term styrene exposure above 10 ppm. There is moderate evidence of a causal association with cancer, but data are not sufficient to allow us to pinpoint specific cancers at risk...

  12. Hospitalsomkostninger ved operation for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, Jes Sanddal; Sørensen, Jan

    2010-01-01

    The aim of the study was to estimate the direct cost of an abdominal aortic aneurysm (AAA) repair and to validate it against the national Diagnostic Related Group (DRG) costs.......The aim of the study was to estimate the direct cost of an abdominal aortic aneurysm (AAA) repair and to validate it against the national Diagnostic Related Group (DRG) costs....

  13. Epidemiologi ved juvenil systemisk lupus erythematosus

    Directory of Open Access Journals (Sweden)

    Odd Vinje

    2009-10-01

    Full Text Available We have previously described the impact of Apgar scores on later major and minor disabilities. According to these and other studies, children with low Apgar scores have to show symptoms of neonatal encephalopathy in the first week of life to be at risk of developing later disabilities. Information on neonatal encephalopathy has traditionally been less accessible than Apgar scores in The Medical Birth Registry of Norway (MBRN. In the present study the possibility of extracting information on neonatal encephalopathy from the new notification form to the MBRN, which was introduced in late 1998, was investigated. The introduction of specific and generally accepted definitions of neonatal diagnoses combined with more comprehensive reports to MBRN from the neonatal departments may render registry based studies on neonatal encephalopathy possible in the future

  14. Assisteret reproduktion ved HIV-infektion

    DEFF Research Database (Denmark)

    Kazlauskaite, Ramune; Østergaard, Lars; Laursen, Tinne

    2009-01-01

    horizontal nor vertical infection occurred. CONCLUSION: Our study confirms that insemination is a good first-choice treatment in respect to chance of pregnancy and risk for virus transmission in HIV-seropositive couples in cases without indication for IVF. Udgivelsesdato: 2009-Apr-27......INTRODUCTION: In Denmark assisted reproductive treatment to HIV discordant couples is offered in order to minimize risk of horizontal transmission of virus. MATERIAL AND METHODS: The outcome of 24 HIV-seropositive couples referred with a wish for parenthood to Aarhus University Hospital, Skejby......, between September 1999 and December 2007 was reviewed on the basis of prospectively collected data. A total of 18 couples were offered treatment. RESULTS: In all, eight couples achieved 17 pregnancies, six by home-insemination, ten by homologous intrauterine insemination, and one spontaneously. Neither...

  15. Resultater efter primaer stapedotomi ved otosklerose

    DEFF Research Database (Denmark)

    Wanscher, Jens; Grøntved, Aksel; Faber, Christian

    2009-01-01

    performed using small-fenester-technique in the period 1996-2005. Five experienced ear surgeons performed the operations. The surgeons were still in the learning phase with regard to otosclerosis surgery. RESULTS: A significant improvement was found regarding the air-conduction pure tone average (PTA) (52.......8 dB to 31.4 dB), the bone conduction PTA (25.2 dB to 23,1 dB), air-bone gap (27.6 dB to 8.3 dB), and the speech reception threshold (44.8 dB to 22.5 dB). One operation (0.6%) resulted in severe sensory-neural hearing loss, while other types of complications were seen after 7,2% of the operations...

  16. VEDs for charged particle accelerators: Indian scenario

    International Nuclear Information System (INIS)

    Bhandari, R.K.

    2012-01-01

    In the initial times after their invention, the charged particle accelerators have, primarily, been used for fundamental studies on nuclei and atoms. From the first modern accelerator, the cathode ray tube, used by J.J. Thomson for the discovery of electron, very recently the gigantic 27 km circumference Large Hadron Collider (LHC) is operational in the search of Higg's boson and related physics issues. Particle accelerators have emerged as powerful microscopes for investigating the finest details of cells, genes, molecules, atoms, protons, neutrons, muons, electrons, quarks and, possibly, still undiscovered even more fundamental constituents of the universe, such as dark matter and dark energy. Several noble prize winning discoveries have been made using accelerators. Accelerators are now being used in a wide area of industrial and medical applications. They are used for the production of radioisotopes for medical imaging, cancer therapy, food sterilization, treatment of waste water, sterilization of medical equipment, material modification, mass spectroscopy, cargo scanning, fabrication of semiconductors etc. Ongoing effort towards the development of accelerators with megawatt beam power is showing hope for a cleaner source of nuclear energy and treatment of nuclear waste. Several tens of thousands of accelerators are presently operational in the world for basic research and applications. Development of new accelerators has several times been driven by new technologies and materials and sometimes they have driven the technological developments towards cutting edge. Some examples are ultra-high vacuum in large volumes, superfluid helium in cryogenics, cryocoolers, superconducting magnets and RF cavities, high power vacuum electronic devices, global control systems, superfast computing and communication networks, giant data storage/processing systems etc. India has been pursuing a fairly robust programme of accelerator development at various institutions. It started, primarily, with accelerator construction for basic and applied research, Some accelerators have also been operating for medical purposes

  17. Definition, klassifikation og epidemiologi ved whiplash

    DEFF Research Database (Denmark)

    Jensen, Troels Staehelin; Kasch, Helge; Bach, Flemming Winther

    2010-01-01

    . In a fraction of patients, long-term symptoms with pain and cognitive and emotional symptoms may occur, causing long-term disability. The pathophysiology is unclear. Most research groups favor a multifactorial pathophysiology similar to that observed for other chronic pain conditions without a clear nociceptive...

  18. Besøgscenter ved fregatten Jylland

    DEFF Research Database (Denmark)

    Lund, Nils-Ole

    2005-01-01

    Det maritime besøgscenter består af riggerværksted, et værfts- og bådbyggeri og en værkstedsbygning til smed, tømrer, snedker og maler - mens museumsafsnittet består af udstilling, auditorium, cafe og administration i en lang bygning, der markerer indgangen til udstillingsområdet.......Det maritime besøgscenter består af riggerværksted, et værfts- og bådbyggeri og en værkstedsbygning til smed, tømrer, snedker og maler - mens museumsafsnittet består af udstilling, auditorium, cafe og administration i en lang bygning, der markerer indgangen til udstillingsområdet....

  19. Bæredygtige systemleverancer ved renovering

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2014-01-01

    System (PSS). This thesis presents the hypothesis that system deliveries may be cast as Product-Service Systems, creating the pre-conditions for sustainable integrated product deliveries. Case Studies Renovation case studies have evinced partial use of system deliveries in recent years; however......-of-sales er dermed relevant for bæredygtige leverancer, der disse kræver at ansvaret forbliver hos systemejeren over leverancens hele livscyklus, fra produktion til bortskaffelsen. Denne type produkt kendes fra andre områder under navnet Product-Service-System (PSS). I afhandlingen opstilles derfor hypotesen...... om at systemleverancer kan udformes som Product-Service-Systems og at dermed skabes forudsætningerne for bæredygtige systemleverancer. Casestudier Casestudier om renovering har desuden vist, at der til dels anvendes systemleverancer til renovering i de sidste år, men at disse leverancer sjældent er...

  20. Bio-Matematik ved Roskilde Universitet

    DEFF Research Database (Denmark)

    Ottesen, Johnny T.

    2010-01-01

    findes i monografierne "Applied Mathematical Models in Human Physiology", "Mathematical Modeling in Medicine", og i "The Biomedical Engineering Handbook".   Arbejdet med at udvikle anæstesisimulatorerne satte gang i en mængde "sundhedsmatematik" på instituttet og i dag huser instituttet desuden phd......-programmet "Mathematical modeling and its mathematical prerequisites" ledet af undertegnet. Programmet er associeret med den nationale phd-skole "Research School for Mathematics and Applications".   BioMath-gruppens fokusområder er bl.a. 1) Kardiovaskulær fysiologi og dets kontrolmekanismer; 2) Fluiddynamik og klapløse......-trivielle eksperimenter, kan tjekke om tanker og hypoteser holder og er konsistente samt kan benyttes til at konstruere nye diagnosticerings- og behandlingstilbud, gør at de nævnte metaaspekter er ikke-trivielle aspekter og illustrerer samtidig modelleringslandskabets komplekse moras.   I artiklen forsøger vi...

  1. Vellykket konservativt behandlet caecumperforation ved Ogilvies syndrom

    DEFF Research Database (Denmark)

    Lang, Christian Lyngsaa; Haveman, Maria Cecilie; Achiam, Michael

    2013-01-01

    The case report describes a 37-year-old woman who was diagnosed with Ogilvie's syndrome after caesarean section. Conservative treatment was initiated with minimal effect, and the patient was subsequently treated with IV neostigmine. A computed tomography of the abdomen revealed enlarged peritonea...

  2. Definition, klassifikation og epidemiologi ved whiplash

    DEFF Research Database (Denmark)

    Jensen, Troels Staehelin; Kasch, Helge; Bach, Flemming Winther

    2010-01-01

    A whiplash trauma is caused by an acceleration-deceleration force transferring its energy to the cervical spine. Whiplash-associated disorder (WAD) refers to the symptoms that develop after a whiplash injury. The prognosis is favorable with recovery in over 90% of the injured subjects. In a fract......A whiplash trauma is caused by an acceleration-deceleration force transferring its energy to the cervical spine. Whiplash-associated disorder (WAD) refers to the symptoms that develop after a whiplash injury. The prognosis is favorable with recovery in over 90% of the injured subjects....... In a fraction of patients, long-term symptoms with pain and cognitive and emotional symptoms may occur, causing long-term disability. The pathophysiology is unclear. Most research groups favor a multifactorial pathophysiology similar to that observed for other chronic pain conditions without a clear nociceptive...

  3. Randomiseret klinisk undersøgelse af effekten af kognitiv adaptationstræning: design og metodediskussion

    DEFF Research Database (Denmark)

    Hansen, Jens Peter; Østergaard, Birte; Nordentoft, Merete

    2009-01-01

      Kognitiv adaptations træning er afprøvet gennem randomiserede studier i udlandet, men er ikke afprøvet på nydebuterede patienter, som modtager intensiv pleje og behandling. I denne artikel præsenteres et forskningsprojekt, som skal afgøre om kognitiv adaptations træning er velegnet i en dansk...... kontekst som supplement til nuværende tilbud til patienter med debuterende skizofreni. Studiet gennemføres som et randomiseret multicenter forsøg, hvor 164 konsekutivt inkluderede patienter fordeles til henholdsvis kognitiv adaptations træning og standardbehandling. Effekten af interventionen evalueres med......, fordelingsprocedure, bortfald, udvælgelse af patienter og sammenlignelighed mellem tilknyttede centre. Dette studie er det første studie, hvor kognitiv adaptations træning sammenlignes med et ambulant tilbud bestående af psykiatrisk behandling kombineret med hyppige hjemmebesøg ved distriktssygeplejersker. Studiet...

  4. Vulvær intraepitelial neoplasi

    DEFF Research Database (Denmark)

    Hansen, Signe Østergaard; Vorbeck, Christina Steen; Meinert, Mette

    2018-01-01

    Vulva dysplasi skal anses for en præmalign tilstand. Ny histologisk inddeling af vulva dysplasi fra januar 2018: HSIL (High grade Squamous Intraepithelial Lesion) i vulva og Vulvær intraepitelial neoplasi, differentieret VIN (dVIN) Vi anbefaler medicinsk behandling med imiquimod som 1. valg. Dog ...... der stor recidivrate både ved medicinsk og kirurgisk behandling. English summary: Vulva intraepithelial neoplasia (VIN) is a rare but premalignant condition. VIN has two etiological pathways: a human papillomavirus (HPV)-dependent pathway, vulvar HSIL, affecting young women, and an HPV......-independent pathway, differentiated VIN (d-VIN), associated with lichen sclerosus, affecting older women. D-VIN is more aggressive than vulvar HSIL. In case of symptoms, a biopsy should be performed. The recurrence risk is high at 25-50% regardless treatment type. We recommend treatment with imiquimod as first choice...

  5. Træ og Stål i Havvand

    DEFF Research Database (Denmark)

    Jensen, Jens Kristian Jehrbo

    Dette kompendium behandler træ- og stålkonstruktioners holdbarhed i marint miljø. Materialerne bliver udsat for kraftige påvirkninget· i form af bølgeslag, strø ninger, slid, nedbrydning og korrosion. Relevante mekanismer og beskyttelsessysleaer behandles . J~ftet tænkes anvendt ved undervisninge...... , spec ielt på anlægssektorens 6. semester, men andre interesserede er velkomne til at benytte det. Renskrivningen er foretaget af Tove Jensen, og Ingrid Christensen og Poul Skørbæk Sørensen har udført tegnearbejdet. Tak for veludført arbejde! Jens Kr . Jehcbo Jensen...

  6. Evaluering af 'Tankerne på plads og hverdagen tilbage' - et kursusforløb for modermærkekræftramte

    DEFF Research Database (Denmark)

    Haslam, Trine Lolk

    af modermærkekræft til at genvinde trygheden og kontrollen i deres liv, ved at gøre dem bedre i stand til at forstå, acceptere og håndtere deres sygdom og behandling, samt at reducere de modermærkekræftramtes brug af sundhedsvæsenet til det nødvendige. Således ønskes det at påvirke adfærd på kort og...... behandlingen samt give en tilbagemelding på operationsforløbet. På kurset underviser desuden en psykolog, der behandler de psykologiske aspekter ved det at få en livstruende sygdom, hvilket ligeledes er af stor betydning for kursisterne. Desk study underbygger dette ved at pointere, at patientskole med...... formidling af viden via forskellige metoder, giver positiv effekt. Analysen i forbindelse med programteori 2 underbygger at kurset er tilrettelagt og gennemført som gruppebaseret undervisning, hvilket jf. desk study bidrager til øget egenomsorg. Den procesorienterede dialogiske tilrettelæggelse og...

  7. Naturlig ventilation i enfamiliehuse

    DEFF Research Database (Denmark)

    Bergsøe, N.C.

    Meddelelsen beskriver resultaterne af en række beregninger foretaget ved anvendelse af et computerprogram. Beregningerne har til formål at belyse forskellige parametres indvirkning på funktionen af et naturligt ventilationssystem. Blandt andet belyses systemets afhængighed af aftrækskanalernes di...... dimension, udeluftventilarealet og placeringen af aftrækskanalernes udmunding i tagfladen. Derudover gengives i kortfattet form de væsentligste konklusioner af udvalgte publikationer, som behandler særlige forhold vedrørende naturlig ventilation i praksis....

  8. Mindfulness som smertehåndteringsredskab for kvinder med endometriose

    DEFF Research Database (Denmark)

    Jensen, Mette Kold; Vedsted-Hansen, Hanne; Hansen, Tia G. B.

    2011-01-01

    Endometriose er en kronisk underlivssygdom med smerter og en række afledte problemer, som ikke nødvendigvis kan behandles med lægelige tiltag. Artiklen argumenterer for, at en mindfulness-baseret tilgang med fokus på smertehåndtering kan anvendes til denne klientgruppe. I vestlig terapeutisk...... sammenhæng kan mindfulness karakteriseres som nærvær, observation og beskrivelse af sansninger uden vurdering eller reaktion. Mindfulness-træning har effekt mod andre typer stress og kroniske smerter, og artiklen opridser et koncept til anvendelse ved endometriose. Konceptet belyses med en case, hvor...

  9. Nyd det! Nyd det!

    DEFF Research Database (Denmark)

    Jantzen, Christian; Østergaard, Per

    2007-01-01

    utilsigtet konsekvens af en række faktorer, der i fællesskab bibringer det indtryk, at det er godt at nyde. Vekselvirkningen mellem modernitetens strukturelle vilkår og oplevelsesorienteringen er, at der er frembragt en teknik, et sprog og en ideologi for den ønskværdige måde at nyde på.......Artiklen behandler de mentalitetshistoriske forudsætninger for den moderne hedonisme, som er kendetegnet ved forbrugere, der kyndigt manipulerer med deres sanser, fantasier og behovstilfredsstillelse for at opnå maksimal nydelse. Den moderne oplevelsesorientering skal ses som en dybest set...

  10. Websiteanalyse

    DEFF Research Database (Denmark)

    Thorlacius, Lisbeth

    2014-01-01

    Studier i design og analyse af æstetiske aspekter i planlægning og brug af websites har kun i et begrænset omfang været under reflektorisk behandling. Det er baggrunden for dette kapitel, som indleder med en gennemgang af æstetikkens rolle i webdesign for derefter at se på genrer og stilarter i...... webdesign. Efterfølgende opstilles en model til analyse af visuel kommunikation på websites. Modellens teoretiske grundlag vil blive introduceret, og dens praktiske anvendelse vil blive demonstreret ved en sammenlignende analyse af Københavns Kommunes og multikunstner Henrik Vibskovs hjemmesider og Facebook-sider....

  11. Tegn på læring ved bruk av interaktive matematikkutstillinger ved vitensenter

    Directory of Open Access Journals (Sweden)

    Nils Kr. Rossing

    2016-04-01

    Full Text Available Interactive exhibits at science centres are believed to have a learning effect on visitors. This study investigates two interactive exhibits concerning mathematics at the Science centre in Trondheim, Norway, to what extent they appeal to the audience, and contributes to constructive thought processes that provide for learning. I was also looking for characteristics of the exhibits that might obstruct such thought processes. During the study we observed more than 170 visitors while they used the two exhibits. In addition I observed and interviewed seven teenagers hired specifically to work with the exhibits. Since the audience are completely free to use the exhibits as they like, it is assumed that there is a high correlation between time spent at the exhibits and public involvement. By measuring the average time for every age group, it was found that the exhibits engaged teenagers and adults to a high degree. Also children below 13 years of age used the exhibits diligently, but then in other ways than intended. Some major obstacles that the design of the exhibits let in the way of creating constructive thought processes among the audience were identified. For example, it was found that removing the time limitation of solving tasks and giving the audience the greatest possible transparency and control over the exhibits, a better basis for discussions and reflections was laid. This is an important premise for learning. Furthermore, changes in conditions were made in order to encourage the audience to try out new strategies.

  12. Rusmidler og mundhulen

    DEFF Research Database (Denmark)

    Pedersen, Anne Marie Lynge

    2016-01-01

    millioner af dødsfald, især alkoholmisbrug. Cannabis er det mest almindeligt anvendte illegale stof i hele verden, men der produceres til stadighed nye stoffer på verdensmarkedet. Litteraturen om virkningerne af illegale stoffer på den orale sundhed er relativ sparsom på grund af vanskeligheder med...... bruksisme. Desuden er det velkendt, at overdreven indtagelse af alkohol øger risikoen for oral cancer betydeligt. Det er vigtigt, at tandlæger har et indgående kendskab til de kliniske manifestationer ved misbrug og de medicinske risici, der kan være ved behandling af patienter med misbrug, men også...

  13. TV-Hybridgenrer mellem fakta og fiktion

    Directory of Open Access Journals (Sweden)

    Jørgen Stigel

    1986-08-01

    Full Text Available I denne artikel behandler Jørgen Stigel de seneste års ud- vikling i nogle af fjernsynets genrer. Hans synsvinkel er den, at TV-mediet først nu er ved at etablere sine "egne" genrer, f.eks. faktion og docu-drama - der ved første øje- kast tager sig ud som blandinger af de genrer, vi kender fra andre medier. Efter en indledende diskussion af de vil- kår, der gælder for faktaformidling i et stadig mere under- holdningspræget TV-univers, analyserer Jørgen Stigel nogle nyere danske eksempler på dybdeborende research-journali- stik, med hovedvægten på Sten Baadsgaard og Jørgen Peder- sens udsendelse om Tvind.

  14. Salmonella typhi--tid til aendring af den empiriske behandling

    DEFF Research Database (Denmark)

    Gade, Christina; Engberg, Jørgen; Weis, Nina

    2008-01-01

    In the present case series report we describe seven recent cases of typhoid fever. All the patients were travellers returning from Pakistan, where typhoid is endemic. Salmonella typhi isolated from the patients by blood culture were reported as intermediary susceptible to fluoroquinolones in six...... out of seven cases. We recommend that empiric treatment of suspected cases of typhoid fever includes a third generation cephalosporin such as ceftriaxon. Furthermore, the present report stresses the importance of typhoid vaccination of travellers to areas where typhoid is endemic. Udgivelsesdato: 2008...

  15. Der er store barrierer for psykiatrisk behandling i lavindkomstlande

    DEFF Research Database (Denmark)

    Sørensen, Carina Winkler; Bæk, Ole; Carlsson, Jessica

    2015-01-01

    Huge barriers to the treatment of mental disorders in low-income countries In low-income countries 76-85% of people living with mental disorders do not receive treatment. To reduce the treatment gap many challenges need to be addressed. On a health political level this includes limited financial...... resources and ineffective health organization. Human resources are inadequate, and often drugs are not available. Individuals face long distances to psychiatric hospitals, out-of-pocket payment and stigma. There is a great need for research in how to enhance prevention and treatment of mental disorders...

  16. Sammenlimning af begge øjne skal ikke behandles konservativt

    DEFF Research Database (Denmark)

    Øgard, Carsten; Kjaerbo, Hadi; Sørensen, Torben Lykke

    2010-01-01

    We describe a case of a 4-year-old boy who accidentally had both eyes glued together. The eyelashes were cut and the boy's eyelids were separated in general anaesthesia. When both eyes are glued together, we do not recommend expectancy, especially not in paediatric cases. For psychological reason......, the lids should be separated surgically. Furthermore, we suggest that similarities between ophthalmic bottles and superglue bottles are avoided so that future incidences may be avoided....

  17. Ikkekirurgisk behandling af lumbal nerverodspåvirkning

    DEFF Research Database (Denmark)

    Andersen, Mikkel Østerheden; Andresen, Andreas K; Lorenzen, Marianne Dyrby

    2017-01-01

    evidence is found regarding non-surgical treatment of patients with lumbar radiculopathy. Physiotherapy, in the form of group sessions, seems to have the best level of evidence. However, evidence is still very limited and of poor quality. No evidence has been found with regards to acupuncture...

  18. Medicinsk behandling af osteoporose hos mænd

    DEFF Research Database (Denmark)

    Eiken, Pia A; Vestergaard, Peter

    2016-01-01

    One in five men over the age of 50 years will suffer an osteoporotic fracture during their lifetime, and men who sustain fractures have an increased mortality risk compared to women. Three bisphosphonates (alendronate, risedronate and zolendronic acid), denosumab, strontium ranelate...

  19. Medicinsk behandling af osteoporose hos mænd

    DEFF Research Database (Denmark)

    Eiken, Pia A; Vestergaard, Peter

    2015-01-01

    One in five men over the age of 50 years will suffer an osteoporotic fracture during their lifetime, and men who sustain fractures have an increased mortality risk compared to women. Three bisphosphonates (alendronate, risedronate and zolendronic acid), denosumab, strontium ranelate...

  20. Karkirurgisk behandling hos patienter med påvirket nyrefunktion

    DEFF Research Database (Denmark)

    Hensler, M K; Forrest, M; Lorentzen, Jørgen Ewald

    1994-01-01

    The purpose of the study was to evaluate the effect of surgery for renal artery stenosis in patients with impaired renal function. The design was a retrospective investigation with follow-up. The material consisted of 42 such patients operated at Rigshospitalet between 1980 and 1990. Renal functi...

  1. Behandling af postoperative, kolorektale anastomosestenoser med selvekspanderende plastikstent

    DEFF Research Database (Denmark)

    Lykke, Jakob; Meisner, S.

    2008-01-01

    We report two cases of a benign post-operative stricture of the recto-sigmoid colon managed by insertion of a self-expanding coated plastic stent (SEPS). Both patients presented symptoms of stenosis which dilatation did not relieve. Both patients refused surgical intervention. Instead...... the strictures were managed by insertion of a SEPS. The clinical symptoms disappeared after SEPS insertion. We conclude that SEPS may represent a possible therapeutic tool in selected cases with benign post-operative stenosis of the recto-sigmoid colon Udgivelsesdato: 2008/4/7...

  2. Palliativ behandling af patienter med terminal kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    von Plessen, Christian; Nielsen, Thyge L; Steffensen, Ida E

    2011-01-01

    Terminal chronic obstructive pulmonary disease (COPD) and advanced cancer have similar prognosis and symptom burden. However, palliative care of patients with terminal COPD has been neglected in Denmark. We describe the symptoms of terminal COPD and suggest criteria for defining the palliative...... phase of the disease. Furthermore we discuss the prognostic and ethical challenges for patients, their families and their caregivers. Finally, we summarize the current evidence for palliative treatment of dyspnoea and ways to evaluate response to treatment....

  3. Myopati hos en patient i behandling med simvastatin og fluconazol

    DEFF Research Database (Denmark)

    Pedersen, Jens Kristian; Lydolph, Magnus Christian; Somnier, Finn

    2016-01-01

    A 69-year-old female was admitted due to progressive loss of muscle strength following addition of fluconazole to long-term simvastatin treatment. Rhabdomyolysis was suspected and both drugs were discontinued. Forced diuresis was initiated together with a short course of prednisolone. After 21...

  4. Hvorfor og hvornår behandles aktiniske keratoser

    DEFF Research Database (Denmark)

    Wulf, Hans Christian Olsen

    2014-01-01

    in the hyperkeratotic AK. Visible AK and neighbouring invisible AK should be treated. As AK are provoked by UV radiation, protection against UV is essential. This paper comments on a Cochrane review: "Interventions for actinic keratosis" and treatments avaliable in Denmark...

  5. Linezolid som behandling af infektiøs endokarditis

    DEFF Research Database (Denmark)

    Lauridsen, Trine Kiilerich; Arpi, Magnus; Bruun, Niels Eske

    2010-01-01

    In Denmark enterococci causes 15 to 20% of all endocarditis (IE) cases. The development of multi-resistant bacterial strains has increased the need for new antibiotics. Linezolid is an alternative to conventional treatment of infections with gram positive cocci. In this case report linezolid...

  6. Gener efter behandling af almindeligt forekommende akutte øjenlidelser

    DEFF Research Database (Denmark)

    Krogsgaard, M R; Danborg, L; Jensen, P

    1990-01-01

    The aim of the study was to determine the duration of symptoms in patients treated in the emergency room at Glostrup Hospital for acute eye-trouble. Nine common diagnoses were selected for the study. All patients seen during a 2 1/2 month period were asked to complete a questionnaire one week aft...

  7. Kirurgisk behandling af fedme hos børn

    DEFF Research Database (Denmark)

    Hansen, Ann Berit; Gögenur, Ismail; Støckel, Mikael

    2014-01-01

    Morbid obesity in teenagers has become an increasing problem. Conventional diet has not yet shown effective long-term weight loss. Alternatively, bariatric surgery on adolescents has resulted in substantial weight loss, recovery from diabetes, improvement of cardiovascular risk factors and improv......Morbid obesity in teenagers has become an increasing problem. Conventional diet has not yet shown effective long-term weight loss. Alternatively, bariatric surgery on adolescents has resulted in substantial weight loss, recovery from diabetes, improvement of cardiovascular risk factors...... and improvement in psychosocial status. Still, surgery performed on adolescents provides ethical challenges such as the unknown long-term prognosis after surgery. Despite these challenges, in cases of severe intractable obesity or development of life-threatening complications due to obesity, surgery should...

  8. Behandling af centralnervesystemlymfom efter transplantation med monoklonalt antistof og ganciclovir

    DEFF Research Database (Denmark)

    Hansen, P.B.; Al-Farra, G.

    2010-01-01

    A 35-year-old female was diagnosed with a primary central nervous system posttransplant Epstein-Barr-virus-associated lymphoproliferative disorder three years after a renal transplantation. The histological diagnosis of the brain tumour was a diffuse large B-cell lymphoma. The patient had had...... diabetes mellitus for 28 years and was treated with four weekly doses of the monoclonal antibody rituximab, the antiviral drug ganciclovir and high-dose prednisolone, and the immune suppression was reduced. After four weeks of treatment, a control magnetic resonance image showed complete regression...

  9. Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    DEFF Research Database (Denmark)

    El Fassi, Daniel; Nielsen, Claus Henrik; Bendtzen, Klaus

    2006-01-01

    Rituximab (RTX) is a murine/human monoclonal antibody to CD20, a protein expressed almost exclusively on human B-lymphocytes. RTX induces rapid and marked B-cell depletion with beneficial clinical effects in 1/3 to 1/2 of rheumatoid arthritis patients. Treatment is given as two iv. infusions with...

  10. Den haemostatiske balance under behandling med nyere p-pillepraeparater

    DEFF Research Database (Denmark)

    Petersen, K R; Skouby, S O; Sidelmann, Johannes Jakobsen

    1994-01-01

    and concentration of tissue plasminogen activator inhibitor. The ratio between thrombin-antithrombin-III-complexes and fibrin degradation products were unchanged signifying no effect of hormonal intake on the balance between thrombin formation and fibrin resolution. In conclusion, the dynamic balance between...... generation and resolution of fibrin was undisturbed during treatment with both hormonal compounds and our findings do not provide evidence for increased risk of thrombosis in normal women....

  11. Trombosering af mekanisk mitralklapprotese under behandling med dabigatran

    DEFF Research Database (Denmark)

    Thomsen, Jakob Hartvig; Kjaergaard, Jesper; Saust, Laura Trolle

    2014-01-01

    Dabigatran has been approved for prevention of thromboembolic complications in nonvalvular atrial fibrillation. We present a case of thrombosis of a mechanical prosthetic mitral valve during anticoagulation with dabigatran, switched from warfarin. The patient presented with cardiogenic shock, was...

  12. Legionella pneumoni hos patienter, der er i behandling med infliximab

    DEFF Research Database (Denmark)

    Vinter, Hanne; Nielsen, Henrik Ib

    2009-01-01

    Therapy with tumour necrosis factor-alfa inhibitors is widely used in various inflammatory disorders, but adverse events from severe infections with intracellular pathogens may occur. We describe two cases of severe pulmonary legionellosis in patients treated with infliximab for Crohn's disease a...... and psoriasis, respectively. We conclude that legionella infections are probably more frequent in patients receiving immunosuppressive therapy with tumour necrosis factor-alfa inhibitors than in the background population. Udgivelsesdato: 2009-Jan-19...

  13. Muskuloskeletal behandling af 11-årig med artrogrypose

    DEFF Research Database (Denmark)

    Thomsen, Maria Morandi; Thomsen, Stig Aaberg; Due, Pernille

    2010-01-01

    A two-year-old patient was diagnosed with arthrogryposis because of inflected knees (15-20 degrees) and stiff hamstrings. All joints and reflexes were normal. Activities were described as age-appropriate, but the patient walked with inflected knees and increased lumbal lordosis. Physiotherapy...

  14. Evidensbaseret behandling af psykisk syge hjemløse

    DEFF Research Database (Denmark)

    Larsen, Maja; Nordentoft, Merete

    2010-01-01

    A systematic review of the literature shows that it is possible to reduce homelessness among mentally ill homeless persons, partly by offering access to housing and partly by providing intensive care through Assertive Community Treatment. Assertive Community Treatment can, to some extent, decrease...

  15. Diagnostik og behandling af paroksystisk supraventrikulær takykardi

    DEFF Research Database (Denmark)

    Rujic, Dragana; Sundbøll, Jens; Tofig, Bawer Jalal

    2016-01-01

    management strategies. The probable mechanism of paroxysmal SVT can often be diagnosed from the clinical findings and a 12-lead ECG. This review describes the initial evaluation and treatment of patients with paroxysmal SVT, including distinctive features from the most important differential diagnoses....

  16. Behandling af invert papillom med endonasal endoskopisk sinuskirurgi

    DEFF Research Database (Denmark)

    Andersen, Pia Juul; Kjeldsen, Anette Drøhse; Pedersen, Arne Toft

    2002-01-01

    INTRODUCTION: Inverted papilloma is a benign sinonasal tumour and has a marked tendency to recur after surgical excision. The tumour may be associated with malignancy and during growth it may destroy surrounding tissue. The treatment is either lateral rhinotomy or endoscopic sinus surgery. The aim...... of the study was to describe the course of all patients treated with endoscopic sinus surgery at the ENT Department at Vejle County Hospital during the period 1 January to 31 December 1999. MATERIAL AND METHODS: Twenty-eight journals of patients diagnosed with inverted nasal papillomas were reviewed...... with carcinoma. We did not see any serious side effects to the treatment. DISCUSSION: Endoscopic sinus surgery in combination with Caldwell-Luc can be recommended as an alternative treatment to lateral rhinotomy in patients with inverted papillomas. Preoperative staging with CT or MR-scanning, experienced...

  17. Kombineret kirurgisk og onkologisk behandling af kolorektale levermetastaser

    DEFF Research Database (Denmark)

    Bergenfeldt, M.; Jensen, B.V.

    2008-01-01

    Isolated colorectal liver metastases should be referred for multispecialist management at a liver centre. Long-time survival is possible after resection and adjuvant therapy. If unresectable, newer chemotherapy with oxaliplatin, irinitecan, bevacizumab and cetuximab may result in a median survival...

  18. Status og perspektiver for behandling af de kroniske myeloproliferative neoplasier

    DEFF Research Database (Denmark)

    Ocias, Lukas Frans; Holmström, Morten Orebo; Riley, Caroline Hasselbalch

    2015-01-01

    of these malignancies has focused on lowering their inherent thromboembolic risk but with the discovery of the JAK2-V617F mutation and most recently the calreticulin mutations new therapeutic options such as interferon-alpha, JAK2-inhibitors and statins are being contemplated. This article reviews these new treatment...

  19. Flibanserin som farmakologisk behandling af nedsat lyst hos kvinder

    DEFF Research Database (Denmark)

    Eldon, Anne Sofie; Giraldi, Annamaria

    2017-01-01

    Flibanserin was approved by the Food and Drug Administration in the USA in August 2015 as the first drug for the treatment of American women with the dysfunction hypoactive sexual desire disorder (HSDD) and is a 5-HT1A agonist and 5-HT2A antagonist. The neurophysiological effects of flibanserin...... on these receptors are consistent with the clinical effects, i.e. significantly increasing sexual desire and frequency of satisfying sexual experiences. As such, shifting the balance between inhibitory and excitatory neurotransmitters of importance to sexual desire, flibanserin pharmacologically broaches a possible...... new approach to the treatment of HSDD....

  20. Intranasal glukagon til behandling af hypoglykaemi. En fremtidig behandlingsmulighed

    DEFF Research Database (Denmark)

    Carstens, S; Andersen, I; Gustafsson, Ida

    1994-01-01

    Nearly 10% of IDDM patients receiving conventional insulin treatment and about three times as many in intensive insulin therapy yearly experience severe hypoglycaemia (requiring external assistance) The conventional treatment of severe hypoglycaemia is glucagon given intramuscularly by a relative...

  1. Utilfredsstillende langtidsresultater efter konservativ behandling af patellofemoralt smertesyndrom

    DEFF Research Database (Denmark)

    Rathleff, Michael Skovdal; Rasmussen, Sten; Olesen, Jens Lykkegaard

    2012-01-01

    This review overviews the long-term prognosis of conservatively treated patients with patellofemoral pain syndrome (PFPS). Median values of the 16 included studies show that 29% of soldiers, 27.8% of sports active and 24,7% of the general public will become pain free after they are diagnosed...

  2. Ticsundertrykkelse er en ny evidensbaseret nonfarmakologisk behandling af ticslidelse

    DEFF Research Database (Denmark)

    Sørensen, Camilla Birgitte; Debes, Nanette Mol; Skov, Liselotte

    2017-01-01

    Chronic tic disorder and Tourette syndrome are both chronic and impairing neurobiological disorders starting in childhood with a prevalence between 0.4 and 1.6%. Traditionally, pharmacological therapies have been first-line treatment but are often associated with adverse effects. Recently...... behavioural therapy has shown to be effective in treating tics and today both habit reversal (HR) and exposure and response prevention (ERP) are recommended as first-line treatments. HR and ERP are now available for Danish patients. This article describes the evidence and recommendations for both therapies....

  3. Gastroskopisk behandling af penetrerende gastrisk bånd

    DEFF Research Database (Denmark)

    Fonnest, G F; Jess, Per

    1999-01-01

    Gastric wall penetration of a gastric band after operation for morbid obesity is a well known late complication. The treatment is usually reoperation. In this case report we show that a band penetrating the gastric wall can be successfully treated by gastroscopic operation. This technique is more...

  4. Medicinsk behandling af vandladningsproblemer hos mænd

    DEFF Research Database (Denmark)

    Andersen, Jens Thorup; Nordling, Jørgen; Walter, Steen

    2007-01-01

    and antimuscarinic agents is reviewed with suggestions for follow-up. The increasing use of alpha-blockers, 5-alpha-reductase inhibitors, or both for symptomatic BPH has led to a significant decrease in the number of operations for BPH in the last decade. Bothersome nocturia due to nocturnal polyuria may be resolved...

  5. Pancreastraumer hos børn--operativ versus nonoperativ behandling

    DEFF Research Database (Denmark)

    Haugaard, Michael Valentin; Penninga, Luit; Ifaoui, Inge Bøtker-Rasmussen

    2012-01-01

    Pancreatic trauma is more frequent in children than in adults and is often caused by trauma to the upper part of the abdomen. Mortality is low, but morbidity is high. Pancreatic trauma can be treated operatively or non-operatively, but there is disagreement about the optimal treatment strategy fo...

  6. Behandling af pilonidalcyster med neodynium-yttriumaluminiumgranat-laser

    DEFF Research Database (Denmark)

    Lindholt, Christine S; Lindholt, Jes S; Lindholt, Jan

    2008-01-01

    A 23 year-old woman with a nonsupporative pilonidal cyst was successfully treated causally with Nd-YAG laser, and without any recidivate after 9 months follow-up. The mechanism is presumed to be that YAG-laser has a wave-length of 1064 nm. Consequently, the wave penetration through the skin is de...... is deeper than most other lasers before the energy is absorbed in melanin and oxyhaemoglobin, so the contents of the cyst can be reached and destroyed. The treatment could be a very attractive alternative to open surgery. Udgivelsesdato: 2008-Jun-23...

  7. Behandling af pilonidalcyster med neodynium-yttriumaluminiumgranat-laser

    DEFF Research Database (Denmark)

    Lindholt, Christine S; Lindholt, Jes Sanddal; Lindholt, Jan

    2008-01-01

    A 23 year-old woman with a nonsupporative pilonidal cyst was successfully treated causally with Nd-YAG laser, and without any recidivate after 9 months follow-up. The mechanism is presumed to be that YAG-laser has a wave-length of 1064 nm. Consequently, the wave penetration through the skin is de...... is deeper than most other lasers before the energy is absorbed in melanin and oxyhaemoglobin, so the contents of the cyst can be reached and destroyed. The treatment could be a very attractive alternative to open surgery....

  8. Vellykket konservativ behandling af chylopericardium efter koronar bypassoperation

    DEFF Research Database (Denmark)

    Clausen, Jesper Holmbæck; Veien, Karsten Tange

    2012-01-01

    Chylopericardium after thoracic duct injury is a rare but serious complication of thoracic surgery with mortality rates above 50% without intervention. Complications of chylopericardium are malnutrition, immunosuppression, electrolyte derangement and tamponade. This case describes a 67-year...

  9. Behandling af primær og recidiverende ovariecancer

    DEFF Research Database (Denmark)

    Rosendahl, Mikkel; Mosgaard, Berit Jul; Steffensen, Karina Dahl

    2018-01-01

    to centralized, specialized units. The primary treatment comprises surgical total cytoreduction followed by platinum-based chemotherapy. Newer biological agents are added when randomized trials have shown a benefit. Recurrence is managed by chemotherapy alone or repeated radical surgery followed by chemotherapy....

  10. Ranolazin--ny behandling af kronisk stabil angina pectoris

    DEFF Research Database (Denmark)

    Ahlehoff, Ole; Hansen, Peter Riis

    2009-01-01

    Ranolazine sustained-release tablets were recently approved in the EU for chronic stable angina as add-on therapy when symptoms are not controlled with first-line agents. The mechanism of action is thought to involve inhibition of late sodium influx in the heart, which can reduce abnormalities...... of contractility and repolarisation associated with ischaemia. Ranolazine increases the exercise capacity, reduces angina, and diminishes the use of nitroglycerine. The drug has an excellent safety profile and may be a valuable addition to the treatment of chronic stable angina....

  11. Behandling af juvenile angiofibromer med partikelembolisering og endoskopisk kirurgi

    DEFF Research Database (Denmark)

    Thuesen, Anne Daugaard; Jakobsen, John; Nepper-Rasmussen, Jørgen

    2005-01-01

    INTRODUCTION: Juvenile angiofibroma is a benign, rich vascular nasal tumor, and the biggest complication in surgery is the great loss of blood. Since 1997, Odense University Hospital (OUH) has used preoperative particle embolization and endoscopic surgery to combat this problem. MATERIALS...... and may be considered to be satisfactory. DISCUSSION: Endovascular embolization of juvenile angiofibromas followed by endoscopic surgery is considered to be the preferred treatment method today....

  12. Behandling af peritoneal karcinose med laparoskopisk intraperitoneal kemoterapi under tryk

    DEFF Research Database (Denmark)

    Graversen, Martin; Pfeiffer, Per; Mortensen, Michael Bau

    2016-01-01

    Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment option in patients with peritoneal carcinomatosis (PC). PIPAC has proven efficacious in the treatment of PC from ovarian, colon and gastric cancer. PIPAC has a favourable profile regarding safety for patients and occupati......Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment option in patients with peritoneal carcinomatosis (PC). PIPAC has proven efficacious in the treatment of PC from ovarian, colon and gastric cancer. PIPAC has a favourable profile regarding safety for patients...

  13. Klinik, diagnostik og behandling af Lyme-borreliose

    DEFF Research Database (Denmark)

    Ocias, Lukas Frans; Jensen, Bo Bødker; Knudtzen, Fredrikke Christie

    2017-01-01

    Lyme borreliosis is an infection caused by the Borrelia burgdorferi sensu lato complex and transmitted by Ixodes ricinus ticks in Denmark. It can manifest itself in several different forms of which erythema migrans is the most common and is diagnosed by clinical assessment of the characteristic...

  14. Fækal mikrobiota-transplantation til behandling af tarmlidelser

    DEFF Research Database (Denmark)

    Rode, Anne A; Chehri, Mahtab; Petersen, Andreas Munk

    2017-01-01

    Faecal microbiota transplantation (FMT) is the transferral of faeces from a healthy donor to a patient with a disease linked to disturbances in the gut microbiota. The treatment has been implemented at several hospitals in Denmark, and banks with frozen donor stool material have been established........ The effect of FMT for recurrent Clostridium difficile infection is well-documented. FMT cannot be recommended for routine clinical use for inflammatory bowel disease and irritable bowel syndrome because of lack of data from clinical trials....

  15. Evidensbaseret behandling af psykisk syge hjemløse

    DEFF Research Database (Denmark)

    Larsen, Maja; Nordentoft, Merete

    2010-01-01

    A systematic review of the literature shows that it is possible to reduce homelessness among mentally ill homeless persons, partly by offering access to housing and partly by providing intensive care through Assertive Community Treatment. Assertive Community Treatment can, to some extent, decrease...... psychiatric symptoms and increase quality of life. It is evident that by offering housing, homelessness may be reduced, but the comparison of independent housing and group living did not reveal big differences....

  16. Dilemmaer i musikterapeutisk behandling af en traumatiseret flygtning med musikerbaggrund

    Directory of Open Access Journals (Sweden)

    Bolette Daniels Beck

    2016-12-01

    Full Text Available Denne artikel præsenterer et single case-studie af et receptivt musikterapiforløb med en 55-årig syrisk flygtning, som har været udsat for fængsling og tortur på grund af sine aktiviteter som protestsanger og musiker. Der beskrives problemstillinger og dilemmaer relateret til at anvende musik, der både kan trigge traumer, men også vække indre ressourcer. Kortlægning af patientens forskellige personlighedsdele og musikkens evne til integration af dem vil blive belyst gennem teorien om strukturel dissociation.

  17. Årsager, udredning og behandling af abortus habitualis

    DEFF Research Database (Denmark)

    Larsen, Elisabeth Clare; Christiansen, Ole Bjarne

    2012-01-01

    Recurrent miscarriage (RM) is defined as three or more consecutive early pregnancy losses and affects 1% of couples. RM is probably a multifactorial disease and evaluation includes parental karyotyping, testing for uterine anomalies, thyroid dysfunction, thrombophilia and immune factors. Couples...... facing RM should be offered tender loving care; i.e. repeated measurements of hCG and ultrasound scans. Further treatments are directed against the underlying cause: surgery, hormone supplementation, anticoagulation and immunomodulation. However, the effect of these treatments needs further documentation....

  18. Kirurgisk behandling af levertumorer hos børn

    DEFF Research Database (Denmark)

    Rasmussen, Allan; Kvist, Nina; Kirkegaard, Preben

    2008-01-01

    INTRODUCTION: In this paper we review the results of surgical treatment of children with hepatic tumours. MATERIALS AND METHODS: The study comprises 33 children who have undergone lever resection or liver transplantation since 1990. 26 patients had hepatoblastoma, 3 had hepatocellular carcinoma, 2...... had rhabdomyosarcoma, 1 had a mesenchymal tumour, and 1 had a giant haemangioma. RESULTS: Because of the number of patients, we only analyzed the results of the treatment in the hepatoblastoma group. The survival was the same after resection (77.3%) and liver transplantation (75...

  19. Farmakologisk behandling af mild ukompliceret hypertension i almen praksis

    DEFF Research Database (Denmark)

    Paulsen, Maja Skov; Christensen, Bo; Søndergaard, Jens

    2013-01-01

    pressure 90-99 mmHg; no diabetes or cardiovascular disease) did not reduce mortality or morbidity. The evidence for pharmacotherapy in patients having mild/uncomplicated hypertension is weak. However, current Danish guidelines have taken this into consideration in their recommendations of pharmacotherapy......Hypertension is an important risk factor for cardiovascular disease. In Denmark, patients with hypertension are primarily managed in primary care. A recent Cochrane review concluded that pharmacotherapy of patients with mild hypertension (systolic blood pressure 140-159 mmHg; diastolic blood...... to patients with mild/uncomplicated hypertension....

  20. Palliativ behandling af patienter med terminal kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    von Plessen, Christian; Nielsen, Thyge L; Steffensen, Ida E

    2011-01-01

    Terminal chronic obstructive pulmonary disease (COPD) and advanced cancer have similar prognosis and symptom burden. However, palliative care of patients with terminal COPD has been neglected in Denmark. We describe the symptoms of terminal COPD and suggest criteria for defining the palliative...

  1. Palliativ behandling af patienter med terminal kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    von Plessen, Christian; Nielsen, Thyge L; Steffensen, Ida E

    2011-01-01

    Terminal chronic obstructive pulmonary disease (COPD) and advanced cancer have similar prognosis and symptom burden. However, palliative care of patients with terminal COPD has been neglected in Denmark. We describe the symptoms of terminal COPD and suggest criteria for defining the palliative ph...... phase of the disease. Furthermore we discuss the prognostic and ethical challenges for patients, their families and their caregivers. Finally, we summarize the current evidence for palliative treatment of dyspnoea and ways to evaluate response to treatment....

  2. Behandling af kroniske sygdomme hos patienter med demens

    DEFF Research Database (Denmark)

    Pedersen, Hanne; Klinkby, Kristian Skikkild; Waldorff, Frans Borch

    2017-01-01

    , polypharmacy and chronic pain. Ongoing goal setting is important, and advance care planning is recommended. In general, comorbidity must be carefully and holistic assessed and managed according to each patient's general status of health and stage of dementia. As the dementia develops, focus should primarily...

  3. Gastrisk aspirationsbehandling er et muligt alternativ til behandling af fedme

    DEFF Research Database (Denmark)

    Christensen, Marie Møller; Jorsal, Tina; Naver, Lars Peter Skat

    2017-01-01

    Aspiration therapy with AspireAssist is a novel endoscopic obesity treatment. Patients aspirate approximately 30% of an ingested meal through a draining system connected to a percutanous endoscopic gastrostomy tube. AspireAssist was recently approved by the US Food and Drug Administration...

  4. Filetlap til behandling af livstruende tryksår

    DEFF Research Database (Denmark)

    Gunnarsson, Gudjon Leifur; Høimyr, Hilde; Rossi, Paolo Emilio

    2014-01-01

    reconstruction of the defect was performed. The patient made uneventful recovery to normal activity within six weeks and had a stable result after one year follow-up. The case is a reminder of the importance of early intervention and preventive management of pressure ulcers and elaborates the benefits......A 71-year-old multi-morbid, paraplegic male with five pressure ulcers and a left-sided open trochanter fracture with chronic osteomyelitis was admitted to hospital. His condition required exarticulation of the left hip joint. A radical wound revision and a pedicled lower extremity fillet flap...... of interdisciplinary team efforts in the treatment of advanced ulcers....

  5. Graviditet i livmoderhalsen kan behandles konservativt med methotrexat

    DEFF Research Database (Denmark)

    Sørensen, Marie; Clausen, Helle Vibeke

    2011-01-01

    with systemic methotrexate. The patient with the living cervical ectopic pregnancy had stable vital signs during the period of treatment. The patient with the fetal pole was admitted with heavy vaginal bleeding and anaemia and was stabilised before treatment was initiated. She was stable throughout......Two cases of cervical ectopic pregnancy after in vitro fertilization embryo transfer were managed conservatively. One living cervical ectopic pregnancy was treated with intra-amniotic and systemic injection of methotrexate, and the other cervical ectopic pregnancy with a fetal pole was treated...

  6. Antibiotika som primær behandling af appendicitis

    DEFF Research Database (Denmark)

    Hupfeld, Line; Pommergaard, Hans-Christian; Burcharth, Jakob

    2014-01-01

    Acute appendicitis has traditionally been treated surgically. Conservative approach with antibiotic treatment has been suggested as an alternative to the surgical procedure. The available studies on surgery versus antibiotics may indicate the safe use of conservative treatment for uncomplicated...... appendicitis, but the available studies are typically of low quality. Thus, further studies are needed to clarify the role of conservative treatment, and in the meantime appendectomy remains the standard treatment for acute appendicitis....

  7. Tiotropium. Nyt antikolinergikum til behandling af kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Pedersen, Steffen Thirstrup; Lange, Peter

    2003-01-01

    Tiotropium is a new anti-cholinergic drug with a long duration of action designed for maintenance treatment of chronic obstructive pulmonary disease (COPD). Tiotropium is the first drug specifically developed for the treatment of COPD, but it is also amongst the most expensive drugs used for this......Tiotropium is a new anti-cholinergic drug with a long duration of action designed for maintenance treatment of chronic obstructive pulmonary disease (COPD). Tiotropium is the first drug specifically developed for the treatment of COPD, but it is also amongst the most expensive drugs used...... for this condition. The clinical pharmacology of tiotropium and results from published controlled clinical trials are reviewed. It is concluded that tiotropium seems suitable as a symptomatic treatment for patients with moderate to severe COPD (typically a forced expiratorical volume FEV1 predicted...

  8. Behandling af metforminassocieret laktatacidose med hæmodialyse

    DEFF Research Database (Denmark)

    Schousboe, Karin; El Fassi, Daniel; Secher, Erik Lilja

    2012-01-01

    Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two o...... of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis....

  9. Narrativ og evidensbaseret behandling af komplekst traumatiserede mennesker

    DEFF Research Database (Denmark)

    Riber, Karin; Lindvig, Ditte

    2011-01-01

    Many survivors of potentially traumatizing events develop serious psychological problems. This article aims to critically examine two fundamentally different treatment paradigms. The article presents and discusses Michael White's narrative therapy, Metin Basoglu's modified behaviour therapy and F...

  10. Praediktorer for kroniske følger ved whiplashtraume

    DEFF Research Database (Denmark)

    Kasch, Helge; Kongsted, Alice; Carstensen, Tina Birgitte

    2010-01-01

    Prognostic factors for chronic whiplash-associated disorder (WAD) are identified. In WAD grade I-III, 50% report neck pain after one year (30% in background population). There is a female preponderance among WAD cases. 10% develop a work disability, but no gender differences are found. Age, crash......-injury distress was associated with a 2.1 OR for pain after one year and a 2.8 OR for work disability. Intense headache/neck pain and a multitude of non-painful complaints were both associated with a 3.5 to 4.0 times raised risk of work disability after a year....

  11. Neuroendokrine forstyrrelser ved anorexia nervosa - primoere eller sekundoere?

    DEFF Research Database (Denmark)

    Støving, R K; Hansen-Nord, M; Hangaard, J

    1996-01-01

    Anorexia nervosa is associated with multiple endocrine abnormalities. Hypothalamic neuropeptides and monoamines are involved in the regulation of human appetite, and they are changed in several ways in anorexia nervosa. But it remains to be clarified whether these alterations are secondary...... or etiologic. Feeding behaviour in anorexia nervosa is characterised by a strong ambivalence and not by loss of appetite. Hypothalamic amenorrhea is a diagnostic criterion, and is not only secondary as it often precedes the weight loss and persists for a long time after weight and motor activity have returned...... to normal. Hypersecretion of corticotropin releasing hormone seems to be secondary to starvation, but at the same time it may keep up and intensify the anorexia, physical hyperactivity and amenorrhea. Low production of insulinlike growth factor-I and high growth hormone secretion reflects the nutritional...

  12. Atypisk manifestation ved infektiøs endokarditis

    DEFF Research Database (Denmark)

    Pareek, Manan; Hansen, Lars Koch; Rujic, Dragana

    2013-01-01

    Infective endocarditis is a serious disease associated with a high mortality. The initial presentation may be non-specific and misleading, thus delaying correct diagnosis. In this case report, we describe a 46-year-old woman, who presented with symptoms suggestive of systemic lupus erythematosus......, including malar rash, arthritis, acute renal failure and thrombocytopenia, but she was subsequently proven to have infective endocarditis involving the mitral valve. Her rheumatological symptoms diminished after antibiotic therapy and mitral valve surgery....

  13. Nye behandlingsmuligheder ved primær immun trombocytopeni

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Birgens, Henrik Sverre

    2011-01-01

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathog......Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved...

  14. Patofysiologien ved primær immun trombocytopeni

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Birgens, Henrik Sverre

    2011-01-01

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune-mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathog......Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune-mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved...

  15. Ny markør ved trombotisk trombocytopenisk purpura

    DEFF Research Database (Denmark)

    Gøtze, Jens Peter; Hillarp, Andreas; Lindblom, Anders

    2008-01-01

    Thrombotic microangiopathy can be caused by several conditions which are difficult to diagnose from the clinical presentation alone. Deficient enzyme activity of a newly-discovered enzyme, ADAMTS-13, can lead to thrombotic thrombocytopenic purpura (TTP). Lack of ADAMTS-13 activity causes increased...

  16. Hyperfibrinolytisk dissemineret intravaskulær koagulation ved drukneulykker

    DEFF Research Database (Denmark)

    Hattesen, Andreas Lund; Berg, Henrik Karsten; Folkersen, Lars

    2017-01-01

    This article summarizes the current knowledge of drowning-induced hyperfibrinolytic disseminated intravascular coagulation. Drowning induces respiratory failure with ensuing cardiac arrest, hypoxaemia and ischaemia. A coagulopathy is induced by ischaemia, acidosis and hypothermia, and clinically...

  17. Mikrobiologiske forhold ved aggressive former for marginal parodontitis

    DEFF Research Database (Denmark)

    Belstrøm, Daniel

    2016-01-01

    Aggressiv parodontitis er en alvorlig sygdom, der kan manifestere sig klinisk i en lokal og generaliseret form, og som ubehandlet ultimativt kan medføre tandtab i en tidlig alder. Nekrotiserede parodontale sygdomme, herunder nekrotiserende gingivitis, parodontitis og stomatitis, er kliniske tilst...

  18. Ingeniørens rolle ved skabelse af innovative koncepter

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2007-01-01

    sågar også konkurrencer for skolebørn. En af årsagerne til konkurrencerne, er, at mange virksomheder anser konceptudviklingsaktiviteten for værende af stigende vigtighed. Det er interessant at bemærke, når man studerer disse forskellige konkurrencers rammer, regler og mål, at fællesnævneren for alle...... "innovative koncepter"? Først vedrørende en forståelse af "innovation" i den industrielle kontekst. Udover den relativt sikre og simplistiske definition af: innovation = opfindelse + markedsmæssig succes, er der kun ganske få forsøg i den danske industrikontekst på at definere målene for, eller aktiviteterne...... skabt (kerne produktindhold). Indtil videre er der ikke blevet leveret nogle af disse pc?er, så den kan stadig betragtes som et koncept. Men man har i hvert fald gjort sit bedste for at overveje alle teknologiske, sociale og design-aspekter af konceptet. Moralen her er, at vi ingeniører skal skærpe...

  19. Manglende effekt af substitutionsbehandling ved alfa 1-antitrypsin-mangel

    DEFF Research Database (Denmark)

    Dahl, Ronald; Hilberg, Ole; Ottesen, Anders Løkke

    2011-01-01

    Persons with alpha1-antitrypsin (A1AT) deficiency and chronic obstructive pulmonary disease (COPD) have been tested for the clinical value of regular intravenous infusion with A1AT in two small double-blind randomised controlled trials. The trials found a statistical significant reduction...

  20. Færre indikationer for sedation ved respiratorbehandling

    DEFF Research Database (Denmark)

    Strøm, Thomas; Rian, Omar; Toft, Palle

    2012-01-01

    Critically ill patients undergoing mechanical ventilation have traditionally been deeply sedated. In the latest decade growing evidence supports less sedation as being beneficial for the patients. A daily interruption of sedation has been shown to reduce the length of mechanical ventilation and t...

  1. De mest effektive avlsplaner kan findes ved simuleringer

    DEFF Research Database (Denmark)

    Meier, Kristian; Sørensen, Anders Christian; Thirstrup, Janne Pia

    2014-01-01

    Selektion for høj pelskvalitet og store skind foregår i praksis på levende dyr, mens prisen for skindet vurderes efter pelsning. Vores analyser viste positiv men lav korrelation mellem pelskvalitetsegenskaber vurderet på henholdsvis levende dyr og skind. Ydermere fandt vi en negativ korrelation...

  2. Prognostiske markører for vaegttab ved adipositasbehandling

    DEFF Research Database (Denmark)

    Astrup, A V; Buemann, B; Gluud, C N

    1996-01-01

    cessation of treatment. The maximum weight loss (mean 16.2 kg. 95% CI 14.2-18.2) was positively associated to pre-treatment 24-h energy expenditure (EE) (p DHT) (p ... these factors could explain 41% of the variation in maximum weight loss. After 36 weeks only 24-h EE and DHT had predictive power on weight loss. Weight losses in upper and lower tertiles of DHT concentrations were 17.7 kg (14.1-21.4) and 9.8 kg (6.2-13.3) (p ... kg in the upper compared to the lower DHT tertile was 12% (4-32%). At two and a half years follow-up 21 patients had maintained some of the weight loss (54%), while 14 patients had maintained > 5 kg weight loss (36%). High levels of pre-treatment DHT were also associated with better weight loss...

  3. Potentielle skadelige virkninger ved brug af strømpistol

    DEFF Research Database (Denmark)

    Thomsen, Jakob Hartvig; Kjærgaard, Jesper; Hassager, Christian

    2014-01-01

    Conducted electrical weapons (CEW) were invented in the 1970s and are now widely used by more than 16,000 military and law enforcement agencies worldwide. Recent studies have sug-gested that a causal relation of cardiac arrest in humans and utilization of CEW may exist and cardiac capture and fatal...

  4. Validitet af kodning og indberetning ved vaginal prolapskirurgi

    DEFF Research Database (Denmark)

    Ottesen, Marianne

    2009-01-01

    INTRODUCTION: To validate the coding and local registration of vaginal prolapse surgery in 1996-1998, and reporting of such data to the Danish National Patient registry (LPR). MATERIAL AND METHODS: Comparison of different sets of data from the local data base (GS) and LPR, and retrospective study...... as a vaginal prolapse procedure the validity of this being true was 93.6%. 18 non-prolapse procedures were registered as vaginal procedures. The registration was incomplete in 12.5% due to typing or hearing errors or missing codes. The coding was misleading in 11.8%, due to lack of consensus on coding. 86.......6% of errors were passed through from the patient file to GS and LPR. Through simple guidelines misleading use of combination of codes was reduced from 7% to 0.5%. CONCLUSION: The validity of the two sets of GS data, and the reporting from GS to LPR of vaginal surgical procedures is satisfactory on the cpr...

  5. Brug af foetocidium ved sene provokerede aborter i Danmark

    DEFF Research Database (Denmark)

    Christensen, Anne Vinggaard; Petersson, Birgit

    2012-01-01

    As a result of prenatal screening, the number of late terminations of pregnancy is increasing in Denmark. The fact that the foetus sometimes shows signs of life after the termination is a large concern for health-care staff and parents. In other countries feticide is performed intrauterinely to e...... to ensure that the foetus is dead before the delivery. In Denmark this method is legally used in foetal reduction, but not in late termination of pregnancy. In the light of international literature on the subject, perspectives on feticide in late termination of pregnancy are explored....

  6. Columbus' navn hang ved, da Colombia rev sig fri

    DEFF Research Database (Denmark)

    Østergaard, Uffe

    2016-01-01

    I 52 år har Colombia været skueplads for en særdeles blodig guerillakrig, som har kostet flere end 220.000 mennesker livet. Når den colombianske præsident, Juan Manuel Santos, i morgen på Oslos rådhus modtager Nobels fredspris, er det ikke bare, fordi Nobelkomitéen håber, at den vil give ham styrke...

  7. Sociale, økonomiske og kulturelle aspekter ved whiplash

    DEFF Research Database (Denmark)

    Rasmussen, Claus; Stenager, Elsebeth; Nielsen, Claus Vinther

    2010-01-01

    The sequelae following whiplash injuries (WL) entail considerable human costs and expenses for both treatment and social services, especially public income benefits. Frequently, many players are involved after WL and good intersectional collaboration is therefore essential to counter the WL...

  8. Uventet fund af endobronkial lungetumor ved bronkoskopi hos en storryger

    DEFF Research Database (Denmark)

    Gottlieb, Magnus; Clementsen, Paul Frost; Håkansson, Kåre

    2014-01-01

    A 60-year-old male heavy smoker surprisingly presented with a squamous cell carcinoma in the right upper lobe at bronchoscopy. Combined PET-CT classified the lung cancer as T1aN0M0. However, the endoscopic classification was T2a, which radically reversed the treatment schedule. Conclusions: 1......) A careful bronchoscopy is important even in cases where lung cancer is not expected. 2) Accurate endobronchial classification can be crucial. 3) There is need for training requirements to obtain a satisfactory level of competence in bronchoscopy....

  9. Formidling af uheldsrisikoen ved spirituskørsel

    DEFF Research Database (Denmark)

    Kærup, Simon

    2012-01-01

    Selvom flere forskningsprojekter har påvist unges særlige risiko i Europa, når det kommer til alkohol, så har det vist sig svært at formidle denne risiko til unge bilister. I 2006 påbegyndtes et stort europæisk forskningsprojekt, DRUID (Driving under the Influence of Drugs, Alcohol and Medicines...

  10. Uventet fund af endobronkial lungetumor ved bronkoskopi hos en storryger

    DEFF Research Database (Denmark)

    Gottlieb, Magnus; Clementsen, Paul Frost; Håkansson, Kåre

    2014-01-01

    A 60-year-old male heavy smoker surprisingly presented with a squamous cell carcinoma in the right upper lobe at bronchoscopy. Combined PET-CT classified the lung cancer as T1aN0M0. However, the endoscopic classification was T2a, which radically reversed the treatment schedule. Conclusions: 1) A ......) A careful bronchoscopy is important even in cases where lung cancer is not expected. 2) Accurate endobronchial classification can be crucial. 3) There is need for training requirements to obtain a satisfactory level of competence in bronchoscopy....

  11. Marin recipientundersøgelse ved Thule Air Base 2002

    DEFF Research Database (Denmark)

    Glahder, C. M.; Asmund, G.; Mayer, P.

    I 2002 gennemførte Danmarks Miljøundersøgelser en recipientundersøgelse ud for Thule Air Base (TAB) for at vurdere, om aktiviteterne og specielt de efterladte dumpe på TAB har belastet det marine miljø med forurenende stoffer. Undersøgelsen viser, at der findes flere forurenings-kilder som f. eks...... findes i Wolstenholme Fjord og Bylot Sund området og regionen som helhed. Det væsentligste forureningsproblem i forbindelse med akti-viteterne på Thule Air Base synes at være PCBerne, idet denne kontaminantgruppe viser forhøjede koncentrationer på 2-30 gange både lokalt og regionalt. PCB...

  12. Melæna som debutsymptom ved amyloidose

    DEFF Research Database (Denmark)

    Jessen, Ester M B; Nielsen, Liv Bjerre Juul; Bønnelycke, Marie Kamper

    2015-01-01

    Amyloidosis is a disease characterized by abnormal extracellular deposits of protein. The disease may affect the stomach, however, symptoms are rare in this case. Furthermore, the rare symptoms are diffuse and unspecific and the diagnosis relies on biopsy. We report the case of a 79-year-old fema...... presenting with melaena and no history of amyloidosis. Gastroscopy raised suspicion of a malignant process in the stomach, but biopsy revealed gastric amyloidosis. The treatment of gastric involvement is primarily symptomatic, and causal treatment is reserved for the few....

  13. Cerebral sinustrombose ved Behçets sygdom

    DEFF Research Database (Denmark)

    Schytz, Henrik Winther; Wegener, Marianne; Lassen, Lisbeth Landschoff

    2012-01-01

    ). We present a case of a 32 year-old Lebanese woman with severe headache and papilloedema due to a cerebral venous thrombosis and secondary intracranial hypertension. During follow-up she was diagnosed with bilateral uveitis and a history of recidivating oral and genital ulcerations was disclosed. BD...

  14. Kliniske konsekvenser af intranasal insulinbehandling ved insulinkraevende diabetes mellitus

    DEFF Research Database (Denmark)

    Hilsted, J C; Madsbad, S; Rasmussen, M H

    1996-01-01

    Metabolic control, hypoglycaemia frequency and nasal mucosal physiology were evaluated in 31 insulin-dependent diabetics treated with intranasal insulin at mealtimes for one month and with subcutaneous fast-acting insulin for another month in a randomized crossover trial. During both periods...... subcutaneous doses. The frequency of hypoglycemia was similar during intranasal and subcutaneous insulin therapy, and nasal mucosal physiology was unaffected after intranasal insulin. We conclude that due to low bioavailability and to a high rate of therapeutic failure, intranasal insulin treatment...

  15. Mulighetsstudie for urbant jordbruk ved Gaustadjordet i Oslo

    OpenAIRE

    Espeli, Marthe Bævre

    2017-01-01

    Thesis exploring possibilities for urban agriculture activities at Gaustadjordet, Oslo Gaustadjordet is located in Oslo Kommune, which holds 658 390 inhabitants. (https://www.oslo.kommune.no/politikk-og-administrasjon/statistikk/ befolkning/folkemengde-og-endringer/, 01.01.16) The area is located south of preserved forest areas surrounding the city, and the recreational area of of Sognsvann, northwest of Majorstua, between Blindern and Vinderen metro stations. The area has traditionally be...

  16. Manglende effekt af substitutionsbehandling ved alfa 1-antitrypsin-mangel

    DEFF Research Database (Denmark)

    Dahl, Ronald; Hilberg, Ole; Ottesen, Anders Løkke

    2011-01-01

    in the decrease of lung density measured by computed tomographies, but found no clinical nor statistical significant difference in respiratory symptoms, quality of life, lung function, use of medication, exacerbations, respiratory infections or survival. Based on the present evidence A1AT substitution therapy...

  17. Falsk positivt fund ved screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Høgh, Annette; Grøndal, Nikolaj; Lindholt, Jes Sanddal

    2009-01-01

    The incidence of false-positive screening results in connection with ultrasound scans (US) for abdominal aortic aneurysms (AAA) is unknown, but it is presumably a rare occurrence. The estimated predictive values of both false and true screening results are high because abdominal US describes...

  18. Hvad forstår vi ved pragmatiske sprogvanskeligheder?

    DEFF Research Database (Denmark)

    Hansen, Helle Hallenberg; Christensen, Rikke Vang

    2017-01-01

    I artiklen formidles nogle af de opmærksomhedsområder, vi anser for vigtige i det logopædiske arbejde med børn med pragmatiske sprogvanskeligheder, blandt andet det store spænd i karakteristika og mulige problemer med anvendeligheden af en ny diagnostisk kategori, ”Developmental language disorder...... with impairment of mainly pragmatic language”, i ICD-1.1...

  19. Ureterlaesion ved radikal hysterektomi for cancer colli uteri

    DEFF Research Database (Denmark)

    Rolff, M; Bang, T; Bostofte, E

    1996-01-01

    Eight ureter lesions of the ureter occurred among 100 consecutive patients undergoing radical hysterectomy for cancer of the uterine cervix. The management of this problem is discussed, and treatment guidelines for the most commonly seen lesions are proposed. It is concluded that a more liberal use...

  20. Ultralydundersøgelse ved diagnostik og kontrol af pneumoni

    DEFF Research Database (Denmark)

    Skaarup, Søren Helbo; Graumann, Ole; Zhang, Chen

    2015-01-01

    Fast and accurate diagnostic of community-acquired pneumonia (CAP) is of vital importance. Chest X-ray is currently the most used image modality for the diagnosis of CAP. Lung ultrasound (LUS) is an image modality that seems superior to conventional chest X-ray for diagnosing CAP. LUS is better...

  1. Arbejdsmiljøet ved udbud af renovationsarbejde

    DEFF Research Database (Denmark)

    Busck, Ole Gunni

    Forfatteren gennemførte 2003-2005 en undersøgelse for Branchearbejdsmiljådet for transport af danske kommuners praksis i forbindelse med udbud og udlicitering af renovationsopgaver. Formålet var at kortlægge og analysere erfaringerne med varetagelse af arbejdsmiljøhensyn i kommunernes udbud og dr...

  2. Iltbehandling ved akut eksacerbation af kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Ringbaek, Thomas; Lange, Peter; Mogensen, Torben

    2008-01-01

    Acute exacerbation of COPD is a major cause of hospitalisation in Denmark. Most of the patients require supplemental oxygen in the acute phase and some patients continue oxygen therapy at home after discharge. In this paper we discuss the physiological mechanisms of respiratory failure seen...... in acute exacerbations of COPD. The principles for oxygen therapy in the acute phase are described and recommendations for oxygen therapy are suggested....

  3. Helbredsrelateret livskvalitet ved reumatoid artritis. Hvilke faktorer spiller ind?

    DEFF Research Database (Denmark)

    Linde, L.; Sørensen, J.; Østergaard, Morten

    2008-01-01

    Rheumatoid arthritis (RA) is a chronic inflammatory disease causing joint pain, loss of function and decreased health-related quality of life (HRQoL). HRQoL in RA patients is associated with several risk factors; in this paper the evidence relating to the most important risk factors is reviewed. ...

  4. Sammenligning af QuantiFERON og hudtest ved mulig tuberkuloseinfektion

    DEFF Research Database (Denmark)

    Jepsen, Micha; Krause, Tyra Grove; Moryl, Dorte

    2009-01-01

    positive students were found in relation to the index case. Positive TST results and BCG vaccination (p ... to the desired level of safety and the cost for society and for the patients. Udgivelsesdato: 2009-Sep...

  5. Neisseria meningitidis. Lipopolysakkariders patofysiologiske rolle ved meningokoksygdom og septisk shock

    DEFF Research Database (Denmark)

    Pedersen, Mie Østergaard; Pedersen, Dan Sonne; Pedersen, Michael

    2008-01-01

    increased the likelihood of developing an anti-meningococcal immunization strategy based upon the virulence of LPS which may lead to a vaccination against this important pathogen including serogroup B disease. This review summarizes recent findings that may provide a safe, effective prophylaxis and therapy...

  6. Minimal restsygdom ved maligne blodsygdomme I. Baggrund og praeklinisk validering

    DEFF Research Database (Denmark)

    Hokland, Peter; Nyvold, Charlotte Guldborg; Stentoft, Jesper

    2009-01-01

    In haematological malignancies, molecular markers like fusion DNA from balanced translocations, point mutations, or over-expressed genes can now be used not only for diagnosis, but also for determination of the minimal residual disease (MRD) after cytoreduction with a sensitivity by far exceeding...

  7. Cancer kan være differentialdiagnose ved psykiatriske symptomer

    DEFF Research Database (Denmark)

    Eibye, Simone; Speyer, Helene; Benros, Michael Eriksen

    2015-01-01

    We present a patient with psychiatric symptoms as the first manifestation from an undetected brain tumor. The patient had symptoms of psychosis and a prior history with depression. A slight alteration in consciousness was found but no neurological deficits. Blood tests showed increased infection...

  8. Postoperativ strålebehandling ved cancer mammae

    DEFF Research Database (Denmark)

    Overgaard, Marie; Kvistgaard, Marianne Ewertz; Thomsen, Mette Skovhus

    2007-01-01

    with 5%. The effect is most pronounced in patients with a high risk of local recurrence, but is independent of adjuvant systemic treatment. Late radiation effects, in particular cardiac mortality can now be avoided using modern treatment technique. However, there is a continuous need to find the overall...... balance between the risk and benefit of RT based on individual prognostic parameters and technical possibilities. Udgivelsesdato: 2007-Sep-3...

  9. Alvorlige bivirkninger ved P-pillebrug hos teenagere

    DEFF Research Database (Denmark)

    Nylander, Malin Chatarina; Clausen, Helle V

    2014-01-01

    PubMed-search found studies investigating adverse effects of combined oral contraceptive pills (COC) among teenagers. Four studies found a small negative impact of COC on acquisition of bone mineral density. COC is associated with elevated risk of venous thrombotic events (VTE), especially during...

  10. Alvorlige bivirkninger ved p-pillebrug hos teenagere

    DEFF Research Database (Denmark)

    Nylander, Malin Chatarina; Clausen, Helle V

    2014-01-01

    PubMed-search found studies investigating adverse effects of combined oral contraceptive pills (COC) among teenagers. Four studies found a small negative impact of COC on acquisition of bone mineral density. COC is associated with elevated risk of venous thrombotic events (VTE), especially during...

  11. Bronkodilaterende inhalationsanaestetika ved asthma bronchiale og status asthmaticus

    DEFF Research Database (Denmark)

    Pedersen, C M; Stjernholm, P H; Hansen, T G

    1994-01-01

    On the basis of a review of the literature, a survey is presented concerning the use of halogenated inhalational anaesthetics (halothane, enflurane, isoflurane) in anaesthesia of asthmatic patients and in intensive care units in the treatment of status asthmaticus refractory to maximal standard t...

  12. Potentielle skadelige virkninger ved brug af strømpistol

    DEFF Research Database (Denmark)

    Thomsen, Jakob Hartvig; Kjærgaard, Jesper; Hassager, Christian

    2014-01-01

    Conducted electrical weapons (CEW) were invented in the 1970s and are now widely used by more than 16,000 military and law enforcement agencies worldwide. Recent studies have sug-gested that a causal relation of cardiac arrest in humans and utilization of CEW may exist and cardiac capture and fat...... arrhythmia have been documented in animal studies. We believe, based on current knowledge, that CEW use may have caused human fatalities. Users should be aware of potential serious side effects and be able to provide basic life support....

  13. Otoneurologisk udredning ved akut opstået svimmelhed

    DEFF Research Database (Denmark)

    Hansen, Søren; Ninn-Pedersen, Mirjana; Thomasen, Per Caye

    2011-01-01

    Benign paroxysmal positional vertigo, vestibular neuronitis and Menière's disease cause most cases of acute vertigo. However, doctors must consider central neurological reasons to vertigo. If it is determined that a patient has oto-neurological vertigo, the next task is to determine whether...... the patient has a peripheral or a central cause of vertigo, if the condition is potentially lethal and if there is a need for acute radiological imaging and/or medical intervention. This review highlights the oto-neurological approach to the dizzy patient with particular focus on the patient's history...

  14. Intensiv versus standardbehandling ved debuterende psykose--sekundaerpublikation

    DEFF Research Database (Denmark)

    Bertelsen, Mette; Jeppesen, Pia; Petersen, Lone

    2009-01-01

    A total of 547 patients with a first episode of psychosis were randomised to two years of intensive early intervention programme (OPUS) versus standard treatment. OPUS treatment consisted of Assertive Community Treatment (ACT) with manuals for family involvement and social skills training. Standard...

  15. Danger-signaler og inflammasomer ved autoinflammatoriske og autoimmune sygdomme

    DEFF Research Database (Denmark)

    Bendtzen, Klaus

    2011-01-01

    NOD-like receptor protein (NLRP)3 inflammasomes. These inflammasomes govern the induction of proinflammatory cytokines such as IL-1ß, IL-18 and IL-33. PRR and inflammasome dysfunctions may underly immunoinflammatory diseases such as gout and other arthritides, type 1 diabetes and arteriosclerosis....

  16. Utilstraekkelig dokumentation af dødelighed ved krig

    DEFF Research Database (Denmark)

    Buhmann, Caecilie Böck; Nielsen, Karoline Kragelund

    2010-01-01

    Mortality estimates can be used for research, to inform or influence policy, for reconciliation processes, to plan health delivery and relief operations and for legal purposes. Many different methods have been applied and each has strengths and weaknesses. Recent years have seen an international...

  17. Terapeutiske vacciner er et nyt behandlingsprincip ved kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Djurhuus, Sissal Sigmundsdóttir; Brasso, Klaus; Berg, Kasper Drimer

    2015-01-01

    Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemotherapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective...... drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management....

  18. Nye diagnostiske tiltag ved akantamøbekeratitis

    DEFF Research Database (Denmark)

    Nielsen, Esben Tranholm; Heegaard, Steffen; Hjortdal, Jesper Østergaard

    2011-01-01

    Acanthamoeba keratitis is a rare but sight threatening condition. A major problem is that the disease is difficult to diagnose and often mistaken for herpes infection in its early stages. We present an update in diagnostics with the presentation of five recent cases of Acanthamoeba keratitis wher...... the use of confocal microscopy and PCR based DNA analysis of epithelial scrapings played a pivotal role. An early diagnose is crucial for achieving a successful outcome....

  19. Nye sygdomsmarkører ved de kroniske myeloproliferative neoplasier

    DEFF Research Database (Denmark)

    Holmström, Morten Orebo; Ocias, Lukas Frans; Kallenbach, Klaus

    2015-01-01

    The chaperone and calcium storing protein calreticulin is coded by CALR, and newly identified mutations in CALR are found in respectively 49-70% and 56-88% of JAK2- and MPL-negative patients with essential thrombocytaemia (ET) and primary myelofibrosis (PMF). A total of 41 mutations have been...

  20. Myokardieskintigrafi. Praecis og omkostningseffektiv billeddiagnostik ved koronarsygdom--sekundaerpublikation

    DEFF Research Database (Denmark)

    Hesse, B.; Petersen, C.L.; Marcassa, C.

    2008-01-01

    Mortality rates due to coronary arterial disease (CAD) have declined as result of improved prevention, diagnosis and management, but CAD remains the leading cause of death. Myocardial perfusion scintigraphy (MPS) provides a cost-effective tool for early detection of CAD in symptomatic individuals...

  1. Forstørret nakkefold kan ses ved osteogenesis imperfecta

    DEFF Research Database (Denmark)

    Schönewolf-Greulich, Bitten; Skibsted, Lillian; Maroun, Lisa Leth

    2011-01-01

    A limited number of reports published since 2001 have described an association between increased nuchal translucency (NT) and osteogenesis imperfecta (OI). We report a new case which underlines the frequency of this association as well as the importance of follow-up and genetic evaluation...

  2. Anvendelse af monoaminooksidasehæmmeren isocarboxazid ved behandlingsresistent depression

    DEFF Research Database (Denmark)

    Larsen, Jens Knud; Krogh-Nielsen, Lene; Brøsen, Kim

    2015-01-01

    The antidepressant efficacy of isocarboxazide is well established; however, the clinical use early became restricted and today the use of isocarboxazide in Denmark is very limited. Isocarboxazide is safe when keeping a low tyramine-containing diet and avoiding concomitant treatment with certain d...... in the official treatment algorithms for patients who are resistant to conventional antidepressant therapy and electroconvulsive therapy....

  3. Også gravide skal rektaleksploreres ved anale symptomer

    DEFF Research Database (Denmark)

    Højgaard, Helle Manfeld; Rahr, Hans

    2012-01-01

    A case of disseminated rectal cancer in a 32-year-old pregnant woman is described. Pain was her main complaint, but this had been ascribed to haemorrhoids and treated with topical agents. She was diagnosed with rectal cancer late in the third trimester when her midwife referred her for surgical a...

  4. Kaffe kan være gavnlig ved leversygdom

    DEFF Research Database (Denmark)

    Kjærgaard, Maria; Thiele, Maja; Krag, Aleksander

    2014-01-01

    Coffee is one of the most commonly consumed beverages in the world. Consequently, it is important to consider the impact of coffee on health and disease. A daily intake of at least three cups of coffee is likely to have beneficial health effects, especially in patients at risk of liver diseases....... Coffee has been associated with decreased liver inflammation, prevention of cirrhosis, reduced steatosis and lower incidence of hepatocellular carcinoma. It is not yet possible to make clear recommendations, but coffee can likely be included as part of a healthy diet for patients with liver diseases....

  5. Rutinemaessig endoskopisk retrograd kolangiopankreatikografi kan ikke anbefales ved galdestenspankreatitis

    DEFF Research Database (Denmark)

    Ainsworth, Alan Patrick; Svendsen, Lars Bo

    2009-01-01

    Danish guidelines recommend that patients with presumed severe gallstone-induced acute pancreatitis (GAP) should receive endoscopic retrograde cholangiopancreatography (ERCP) within 72 hours. The results of a newly performed meta-analysis show that acute ERCP in patients with GAP does not reduce...

  6. Endoskopisk ultralydvejledt rendezvouskolangiografi ved mislykket endoskopisk retrograd kolangiopankreatikografi

    DEFF Research Database (Denmark)

    Boman, Pia Snedker; Perdawid, Sharafaden Karim; Lykkegaard, John

    2012-01-01

    In this case report we describe an alternative method of cholangiography. Endoscopic retrograde cholangiopancreatography (ERCP) was not successful in a patient with choledocolithiasis. A combined endoscopic ultrasound (EUS) and ERCP procedure was performed and a stent was inserted in the common...

  7. Fatalt forløb ved in vitro-fertilisation

    DEFF Research Database (Denmark)

    Sørensen, Martin Kryspin; Møller-Sørensen, Hasse; Svane, Christian

    2010-01-01

    and developed chylomicronaemia syndrome with severe hypertriglyceridaemia, hypertriglyceridaemia-induced acute pancreatitis and septic shock. Appropriate treatment including close monitoring, severe restriction of dietary fat intake and early plasmapheresis is emphasized - especially during pregnancy....

  8. Minimal restsygdom ved maligne blodsygdomme II. Translation og terapeutiske konsekvenser

    DEFF Research Database (Denmark)

    Hokland, Peter; Ommen, Hans Beier; Nyvold, Charlotte Guldborg

    2009-01-01

    in following patients with chronic myeloid leukaemia treated with the tyrosine kinase inhibitor imatinib. Moreover, the methodology is being integrated in an increasing number of clinical trials, where it is expected to result in more rational and individualized clinical decision-making. A special point...

  9. Hungry bone-syndrom ved vitamin D-mangel

    DEFF Research Database (Denmark)

    Chehaiber, Mohamad M; Jensen, Jens-Erik Beck

    2009-01-01

    An 85-year-old woman was admitted after being bedridden for six months with muscular weakness and diarrhoea. Vitamin 25-OH-D, serum calcium, magnesium and phosphate were low, and parathyroid hormone as well as alkaline phosphatase were increased. Dual x-ray absorption scan showed reduced bone...

  10. Anvendelse af præhospital tourniquet ved livstruende ekstremitetstraumer

    DEFF Research Database (Denmark)

    Lyngsaa Lang, Christian; Lauridsen, Trine; Boel, Thomas

    2015-01-01

    Tourniquets have been used for centuries. They have been called lifesavers and "an invention of the evil one". 90.9% of deaths on the battlefields result from haemorrhage. Lessons learned du­ring the wars in Iraq and Afghanistan have developed the treat­ment given to hypovolaemic patients...

  11. Strategier ved udredning af malassimilation. En kritisk status

    DEFF Research Database (Denmark)

    Rumessen, J J

    1997-01-01

    malassimilation. The frequency and clinical importance of this condition is in all probability underestimated. Screening for coeliac disease may be achieved by several serological tests (reticulin-, gliadin-, endomysial antibodies), of which IgA-endomysial antibodies seem superior. Comparative studies are often...

  12. Aflastning af tumorbetinget obstruerede øvre urinveje ved prostatacancer

    DEFF Research Database (Denmark)

    Kraemer, Pia Charlotte; Borre, Michael

    2009-01-01

    INTRODUCTION: Hydronephrosis in patients with prostate cancer can be relieved by nephrostomia or internal urinary diversion by a double-J ureteral stent. The latter can be placed either retrograde or antegrade by means of an already established nephrostomy. The purpose of the present study...

  13. Intra- og interobservatøroverensstemmelse ved gennemsyn af kapselendoskopifilm

    DEFF Research Database (Denmark)

    Laursen, Emilie Lund; Ersbøll, Annette Kjaer; Rasmussen, Anne Mette Odgaard

    2009-01-01

    INTRODUCTION: It is unclear which professional groups can and should perform reviews of capsule endoscopy (CE) exams of the GI tract. We investigate whether a junior doctor or an endoscopy nurse can review CE films with the same diagnostic results as a specialist. MATERIAL AND METHODS: An endoscopy...... nurse and a junior doctor, both with no CE experience, reviewed 30 CE films twice and noted their findings. A distinction was made between clinically important and non-important findings. An endoscopy specialist and the Given Imaging Review Service reviewed the films once each, and their findings were...

  14. HELLP kan ses i andet trimester ved antifosfolipidsyndrom

    DEFF Research Database (Denmark)

    Madsen, Bjørn Stæhr; Havelund, Troels

    2011-01-01

    The syndrome of haemolysis, elevated liver enzymes and low platelets (HELLP) is estimated to occur in 0.01-0.2% of pregnancies and is considered a severe form of preeclampsia. It is associated with considerable risk of maternal and foetal mortality. HELLP syndrome associated with antiphospholipid...... syndrome is known to occur early in the pregnancy. We report a case of severe HELLP syndrome complicated by multiple hepatic infarctions and portal vein thrombosis in the second trimester in a patient with antiphospholipid syndrome....

  15. Laparoskopiassisteret ileocøkal resektion ved Crohns sygdom

    DEFF Research Database (Denmark)

    Laursen, Stig Borbjerg; Knudsen, Torben; Poornoroozy, Peiman

    2010-01-01

    Laparoscopic surgery has become more widely used in the treatment of patients with inflammatory bowel disease. The aim of this study is retrospectively to describe the results of laparoscopy-assisted ileocolic resection of nineteen patients with Crohn's disease.......Laparoscopic surgery has become more widely used in the treatment of patients with inflammatory bowel disease. The aim of this study is retrospectively to describe the results of laparoscopy-assisted ileocolic resection of nineteen patients with Crohn's disease....

  16. Anvendelse af monoaminooksidasehæmmeren isocarboxazid ved behandlingsresistent depression

    DEFF Research Database (Denmark)

    Larsen, Jens Knud; Krogh-Nielsen, Lene; Brøsen, Kim

    2015-01-01

    The antidepressant efficacy of isocarboxazide is well established; however, the clinical use early became restricted and today the use of isocarboxazide in Denmark is very limited. Isocarboxazide is safe when keeping a low tyramine-containing diet and avoiding concomitant treatment with certain d...

  17. Iatrogene duralæsioner ved dekompressionskirurgi i lumbalcolumna

    DEFF Research Database (Denmark)

    Thomsen, Frederik; Amtoft, Ole; Andersen, Mikkel

    2010-01-01

    at the Private Hospital Hamlet. The study covers cases from the 10-month period from September 1, 2007 to June 30, 2008. Data was collected after this period and consists of surgeon-documented dural tears. At the time of surgery, the surgeon was unaware that there would be a subsequent registration. A total...

  18. Noninvasiv vurdering af fibrose ved kronisk viral hepatitis

    DEFF Research Database (Denmark)

    Risum, Malene; Barfod, Toke Seierøe; Lindhardt, Bjarne Orskov

    2013-01-01

    In chronic viral hepatitis the liver biopsy helps the clinician to decide when to start treatment and plan follow-up. However, the execution of a liver biopsy is associated with discomfort, and sampling error can lead to misinterpretation. Serum markers and transient elastography (TE) are being...

  19. Danskernes seksualliv belyst ved befolkningsundersøgelser

    DEFF Research Database (Denmark)

    Eplov, Lene Falgaard; Garde, Karin; Køster, Anne

    2002-01-01

    populations. A total of 34 studies based on a representative material were identified. However, only three studies were nationwide, including both genders and several age groups. The studies elucidate sex education, sexual activity, and sexual practices in regard to risk behavior related to AIDS, whereas...

  20. Ansatte hentede inspiration ved Burning Man-festival

    DEFF Research Database (Denmark)

    Rosenstand, Claus Andreas Foss

    2012-01-01

    Hvert år i den sidste uge af august omdasse en ørken dybt inde i Nevada til mekka for kunst,kreativ innovation og menneskelig udfoldelse......Hvert år i den sidste uge af august omdasse en ørken dybt inde i Nevada til mekka for kunst,kreativ innovation og menneskelig udfoldelse...

  1. Skader ved brug af løbehjul

    DEFF Research Database (Denmark)

    Larsen, Michael Hareskov; Nielsen, Henrik Toft; Larsen, Søren Erik

    2002-01-01

    Since the beginning of the nineties, skate-boards, in-liners, roller skates, and during the past years non-powered scooters have gained increasing popularity. This surge of enthusiasm has resulted in an increasing number of injuries involving scooters.......Since the beginning of the nineties, skate-boards, in-liners, roller skates, and during the past years non-powered scooters have gained increasing popularity. This surge of enthusiasm has resulted in an increasing number of injuries involving scooters....

  2. Overvej cannabinoid hyperemesis-syndrom ved recidiverende opkastninger

    DEFF Research Database (Denmark)

    Nordholm-Carstensen, Andreas

    2014-01-01

    Cannabinoid hyperemesis syndrome (CHS) is characterised by unrelenting nausea, recurrent vomiting, abdominal pain and compulsive, hot bathing behaviour. The symptoms contrast the traditional effects associated with cannabis use. We report a "textbook example" of a 26-year-old man with CHS. CHS...... is an important differential diagnosis to consider in patients with similar symptoms and the distinctive symptom relief in hot water. Early recognition may prevent extensive, unnecessary medical examinations and frequent hospital admissions....

  3. Meningokoksepsis diagnosticeret ved realtids-polymerasekædereaktion

    DEFF Research Database (Denmark)

    Harboe, Zitta B; Howitz, Michael F; Nørgaard, Christina

    2008-01-01

    Approximately 100 cases of meningococcal disease are reported annually in Denmark; 90% of these cases are confirmed by culture and serological methods. Real-time PCR was introduced in Denmark in 2005 as a diagnostic tool for meningococcal disease. We hereby report the first notified case of menin...

  4. Behov for national database ved operation for lumbal spondylodese

    DEFF Research Database (Denmark)

    Rasmussen, Sten; Iversen, Maria Gerding; Kehlet, Henrik

    2010-01-01

    in 2006 was used. RESULTS: There was no difference in patient demographics and diagnosis between public and private clinics. In 62% of the patient files, information was lacking. Considerations on indication and surgery did not differ from public to private clinics. A standard preoperative rehabilitation...... program was performed in 59% of the cases. Combined anterior and posterior fusion was performed in 37 cases, posterior instrumented fusion in 77 cases and posterior uninstrumented fusion in 105 cases, interspinous spacer was used in six cases and disc arthroplasty in 13 cases. CONCLUSION: Adequate...... evaluation of indication and choice of surgical technique in lumbar fusion based on patient files was not possible. We found no qualitative differences between public and private clinics. A national database is needed to monitor indication and choice of operative procedure. Udgivelsesdato: 2010-Nov-22...

  5. Bulkister og Bådgrav ved Bulbrogård

    DEFF Research Database (Denmark)

    Bican, Josefine Franck

    2012-01-01

    oldsager. I seks af gravene var der bevaret kistespor, i fem tilfælde efter bulkister og i ét tilfælde efter en stammebåd anvendt som kiste. Fire af gravene indeholdt gravgods. Gravens konstruktion, udformning og indhold diskuteres med særlig fokus på bådgraven, og der sammenlignes med andre fladmarksgrave...

  6. Overførsel af viden ved flytning af produktion

    DEFF Research Database (Denmark)

    Madsen, Erik Skov; Riis, Jens Ove; Wæhrens, Brian Vejrum

    2010-01-01

    Empiriske studier i tre industrielle virksomheder har afsløret, at selv virksomheder med mange års erfaring i at overføre produktion til andre lande hovedsagelig fokuserer på planlægning af den fysiske overflytning af produktionsudstyr og fokuserer på den eksplicitte viden, der er tilknyttet prod...

  7. Terapeutiske konsekvenser ved lungeskintigrafi med intermediaer sandsynlighed for lungeemboli

    DEFF Research Database (Denmark)

    Marmolin, Ea Sofie; Møller, Louise; Johansen, Allan

    2009-01-01

    INTRODUCTION: Pulmonary embolism has a high mortality and is difficult to diagnose. Lung scintigraphy is widely used. However, a significant number of patients receive an inconclusive result. The aim of this study was to determine how patients with an intermediate result were handled. MATERIAL AN...

  8. Nye prognostiske markører ved kolorektal cancer

    DEFF Research Database (Denmark)

    Nielsen, Hans Jørgen; Brünner, N A; Thorlacius-Ussing, O

    1998-01-01

    The majority of patients diagnosed as having colorectal cancer do not survive five years, although 70%-80% undergo curative surgery. Only a minority of the patients receive additional adjuvant chemo-, radio- and/or immunotherapy, which has proven its efficiency in a minor part of patients...... with Dukes C disease. Therefore, adjuvant therapy has only an insignificant impact on overall survival improvement. The present treatment of patients with colorectal cancer is far from sufficient, and this has led to considerations of how to optimize both surgical and adjuvant medical treatment strategy...... biological markers of development, growth and dissemination of colorectal cancer can be used to predict prognosis either alone or in various combinations, and as selection markers to discriminate between patients who only need surgery and patients who may need adjuvant treatment. Udgivelsesdato: 1998-Aug-3...

  9. Miljøundersøgelser ved Kvanefjeldet 2001

    DEFF Research Database (Denmark)

    Asmund, G.

    jordarter' (La Ce Pr Nd Sm Eu Gd Tb Dy Ho Er Tm Yb Lu) Af de mange grundstoffer, der er undersøgt er det kun 'Sjældne jordarter', zirkonium, niobium og thorium, der viser forhøjelser i forhold til baggrundsværdier og samtidigt er stærkt forhøjede i det vand, der siver ud fra minen. Imidlertid fandtes denne...

  10. Erythropoietin--en ny terapi ved cerebral iskaemi?

    DEFF Research Database (Denmark)

    Kalialis, Louise Vennegaard; Olsen, Niels Vidiendal

    2003-01-01

    as an anti-inflammatory and neuroprotective drug. EPO and its receptor are expressed in neurons, glial cells and brain capillary endothelial cells, and the system is upregulated in conditions of cerebral ischaemia and hypoxia. Animal studies have now established that intracerebroventricular administration...... of recombinant EPO exerts neuroprotection in models of stroke. The mechanisms appear to involve an upregulation of specific anti-apoptotic and anti-inflammatory pathways. In addition, neurotrophic and angiogenetic effects of EPO may contribute in a long latency protection. Interestingly, also systemic...... administration of recombinant EPO ameliorates neuronal damage after brain ischaemia, and prevents the loss of autoregulation of cerebral blood flow following experimental subarachnoid haemorrhage. Recombinant human EPO is a safe and non-toxic drug, and clinical studies are currently investigating...

  11. Nye behandlingsmuligheder ved primær immun trombocytopeni

    DEFF Research Database (Denmark)

    Gudbrandsdottir, Sif; Frederiksen, Henrik; Birgens, Henrik Sverre

    2011-01-01

    Primary immune thrombocytopenia (ITP)--formerly known as idiopathic thrombocytopenic purpura--is an autoimmune disorder characterized by immune mediated thrombocytopenia. The aetiology of ITP remains unknown, but studies have shown that multiple immunological mechanisms are involved in the pathog...

  12. Kloakering i landbruget og ved mindre beboelser i landzone

    DEFF Research Database (Denmark)

    Petersen, H.W.

    Publikationen er beregnet til at bruges sammen med DIF's "Norm for afløbsinstallationer", DS 432, og "Norm for mindre afløbsanlæg med nedsivning", DS 440. Den giver vejledning i planlægning og udførelse af afløbsanlæg med rørledninger i jord for ajle og spildevand ført til opbevaringstank eller v...

  13. Rutinemaessig endoskopisk retrograd kolangiopankreatikografi kan ikke anbefales ved galdestenspankreatitis

    DEFF Research Database (Denmark)

    Ainsworth, Alan Patrick; Svendsen, Lars Bo

    2009-01-01

    Danish guidelines recommend that patients with presumed severe gallstone-induced acute pancreatitis (GAP) should receive endoscopic retrograde cholangiopancreatography (ERCP) within 72 hours. The results of a newly performed meta-analysis show that acute ERCP in patients with GAP does not reduce...... the risk of complications, and ERCP is therefore not to be used routinely in GAP patients. The possible benefits of replacing ERCP with either endoscopic ultrasonography or magnetic resonance cholangiopancreatograhy have yet to be demonstrated. Udgivelsesdato: 2009-Aug-31...

  14. Cyklister undtaget signal ved undertavle i T-kryds

    DEFF Research Database (Denmark)

    Jensen, Morten Lind; Lahrmann, Harry Spaabæk

    2016-01-01

    Som led i fremme af cykeltrafik er der generelt et ønske om at fremme cyklisters fremkommelighed. En af mulighederne er at undtage cyklisterne for signalet i overliggeren i signalregulerede T-kryds. Men hvad betyder det for trafiksikkerheden? I samarbejde med Aalborg Kommune gennem projektet ’Aal...

  15. Støtte til egenomsorg ved kronisk sygdom?

    DEFF Research Database (Denmark)

    Vedsted, Peter; Jørgensen, Bjarne Søgaard; Rytter, Lars

    2010-01-01

    Self-management is part of chronic care to ensure an informed and activated patient. We scrutinised systematic literature reviews about self-care in general practice. There were effects on clinical and patient related measures and health services utilisation. Most effect was seen in interventions...... using health care professionals to provide education about action plans and medical treatment. Patient led education did not show effect on clinical outcome but on patient-related measures. We conclude that general practice should implement self-management as part of chronic care. Udgivelsesdato: 2010...

  16. Ingeniørenes rolle ved skabelse af innovative koncepter

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2007-01-01

    første bølge af miljøhensyn kom med energikrisen i 1970'erne og ebbede ud, da oliepriserne faldt igen. Miljøbølge nummer to udvidede vore horisonter til begrebet bæredygtighed, hvor den treenige overvejelse ”people-profit-planet” forplantede sig i strategiovervejelserne og årsrapporter verden over. Men...

  17. Tastris - så Plinius lyset ved Skagen?

    DEFF Research Database (Denmark)

    Knudsen, Bo Nissen

    2017-01-01

    Vores forfædre begyndte først at skrive meget sent i forhold til de gamle kulturer i Mellemøsten og omkring Middelhavet, og før vikingetiden skal man helt tilbage til de romerske kilder for at finde nedskrevne stednavne fra det område som skulle blive til Danmark. Heriblandt det gådefulde navn Ta...

  18. Sygeplejestuderendes omsorgsforudsætninger ved studiestart i 2002

    DEFF Research Database (Denmark)

    Vedsegaard, Helle Wendner; Rask Eriksen, Tine; Pedersen, Marianne Krogsgaard

    2008-01-01

    The object of the article is to describe the life-history-related care prerequisites of student nurses. The social-scientific study looks at students starting their professional bachelor training in 2002. The methods are based on mapping the population by means of a questionnaire which provides......, certain general and gender-specific care experiences were observed, which were not related to social class. At the same time, the material shows that the girls' social background leaves its mark on the care experiences. The finds are presented in the form of three constructed cases: Middleclass Lone...... nurses. The social-scientific study looks at students starting their professional bachelor training in 2002. The methods are based on mapping the population by means of a questionnaire which provides data about students' life histories. Additionally, nine selected students were interviewed to provide...

  19. Afståelsesbeskatning ved flytning af DEMPE-funktioner

    DEFF Research Database (Denmark)

    Kjærsgaard, Louise Fjord; Bundgaard, Jakob

    2017-01-01

    OECD har i den senest opdaterede version af Transfer Pricing Guidelines fastsat en definition af immaterielle aktiver og har samtidig indført konceptet DEMPE-funktioner, der omfatter visse vigtige funktioner relateret til immaterielle aktiver. SKAT synes at være af den opfattelse, at DEMPE...

  20. Hyperbaric oxygen treatment in radiation reactions; Hyperbar oksygenbehandling ved straalereaksjoner

    Energy Technology Data Exchange (ETDEWEB)

    Aanderud, Leif; Thorsen, Einar; Bratteboe, Guttorm; Forland, Martha; Kristensen, Gunnar

    2000-07-01

    Background: A national hyperbaric centre was established in 1994 at Haukeland Hospital with responsibility of all hyperbaric oxygen (HBO) treatment in Norway. In hypoxic tissues with symptomatic radiation reactions, hyperbaric oxygen induces the formation of collagen and angiogenesis resulting in permanently improved local microcirculation. Material and method: 234 patients received elective HBO treatment at Haukeland Hospital in 12997 with total of 4048 treatments. All 47 patients treated for radiation reactions in the pelvic area in 1997 received a questionnaire 3-15 months after HBO therapy, 81% reported. Results: Rectal bleeding and haematuria were reported as much improved in 61% and 55% respectively, while bladder incontinence was much improved in 46%. Interpretation: this treatment modality may be an alternative in symptomatic radiation reactions at the urinary bladder and the bowel when conventional treatment has given unsatisfactory results.