WorldWideScience

Sample records for behandling af patienter

  1. Behandling af patienter med Guillan Barré syndrom

    DEFF Research Database (Denmark)

    Oliel, Vibeke S.

    2011-01-01

    Resumè Guillain Barrés syndrom er en autoimmum sygdom karakteriseret ved motorisk, sensorisk og autonom dysfunktion. I Danmark rammes omkring 80 personer i alle aldre årligt af sygdommen. Akut inflammatorisk polyradikoloneuropati rammer de perifere nervers nerveskeder og medfører progredierende...

  2. Palliativ behandling af patienter med terminal kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    von Plessen, Christian; Nielsen, Thyge L; Steffensen, Ida E;

    2011-01-01

    Terminal chronic obstructive pulmonary disease (COPD) and advanced cancer have similar prognosis and symptom burden. However, palliative care of patients with terminal COPD has been neglected in Denmark. We describe the symptoms of terminal COPD and suggest criteria for defining the palliative...... phase of the disease. Furthermore we discuss the prognostic and ethical challenges for patients, their families and their caregivers. Finally, we summarize the current evidence for palliative treatment of dyspnoea and ways to evaluate response to treatment....

  3. Karakteristik, diagnostik og behandling af patienter med autoimmun hepatitis

    DEFF Research Database (Denmark)

    Ytting, Henriette; Larsen, Fin Stolze

    2012-01-01

    Autoimmune hepatitis is a relatively rare disease that may lead to rapidly progressing liver cirrhosis and even fulminant liver failure, if diagnosis and treatment is delayed or ineffective. Diagnosing the disease can be challenging, and one in five patients respond insufficiently to standard tre...... treatment. Patients, who are diagnosed late in the disease course or only respond partly to medical treatment, are at high risk of developing severe liver insufficiency. This article summarizes the present knowledge and evidence regarding diagnostics, therapy and disease course....

  4. Bivirkninger ved N-acetylcystein-behandling af paracetamolforgiftede patienter

    DEFF Research Database (Denmark)

    Schmidt, L E; Dalhoff, K P

    1999-01-01

    Treatment of paracetamol intoxication with N-acetylcysteine (NAC) is standard in Denmark. NAC is considered safe with relatively few side effects. It is recommended that all patients be treated irrespective of paracetamol dose or time from intoxication to treatment start. Consequently a higher nu...

  5. Behandling af lokaliseret prostatacancer

    DEFF Research Database (Denmark)

    Jakobsen, Henrik; Iversen, Peter; Mikines, Kári J;

    2007-01-01

    The incidence of prostate cancer is increasing sharply in Denmark and an increasing proportion of patients have clinically localised disease at diagnosis. The therapeutic strategy encompasses intended curative therapy: radical prostatectomy with complete removal of the prostate gland and seminal...... vesicles performed as an open procedure or laparoscopically, external beam radiation therapy, or implantation of radioactive seeds into the prostate (brachytherapy). In older patients with good prognostic factors, active surveillance should be considered. The various therapeutic modalities are reviewed...

  6. Behandling af lokaliseret prostatacancer

    DEFF Research Database (Denmark)

    Jakobsen, Henrik; Iversen, Peter; Mikines, Kári J;

    2007-01-01

    The incidence of prostate cancer is increasing sharply in Denmark and an increasing proportion of patients have clinically localised disease at diagnosis. The therapeutic strategy encompasses intended curative therapy: radical prostatectomy with complete removal of the prostate gland and seminal...... vesicles performed as an open procedure or laparoscopically, external beam radiation therapy, or implantation of radioactive seeds into the prostate (brachytherapy). In older patients with good prognostic factors, active surveillance should be considered. The various therapeutic modalities are reviewed....

  7. Effekt af trombolytisk behandling på udfaldet af tidlig arbejdstest hos patienter med akut myokardieinfarkt

    DEFF Research Database (Denmark)

    Svendsen, Jesper Hastrup; Madsen, J K; Saunamäki, K I;

    1994-01-01

    Exercise test variables, such as an impaired heart rate response, are known to be related to left ventricular function and patient prognosis following acute myocardial infarction. The present study was performed to compare exercise test variables in acute myocardial infarct patients following eit...

  8. Behandling af angste psykiatriske patienter med MusiCure - et pilotprojekt

    Directory of Open Access Journals (Sweden)

    Torben Egelund Sørensen

    2005-02-01

    Full Text Available I perioden 1.11.2003 til 1.3.2004 blev der på to åbne og en lukket sengeafdeling på psykiatrisk afdeling, Horsens sygehus, gennemført et pilotprojekt, med det formål at undersøge om brugen af speciel designet musik (MusiCure ville have en positiv effekt på angste og urolige patienter. 30 patienter fik MusiCurebehandling en eller flere gange, og af disse fik de 26 en positiv effekt af behandlingen: De blev beroliget; faldt til ro/i søvn. For en patient havde behandlingeningen effekt, og for 3 patienter havde behandlingen en negativ effekt. Interviews med patienter og plejepersonalet viste at brugen af MusiCure havde en angstdæmpende effekt, enten givet aleneeller i kombination med PN medicin og /eller kugledyne. Det konkluderes at undersøgelsens samlede resultat tyder på at MusiCure kan anvendes til såvel psykotiske som ikke-psykotiskepatienter, og at MusiCure, anvendt alene eller sammen med kugledyne, kan være et alternativ til brugen af PN medicin. Artiklen er en revideret udgave af artikel med samme titel bragt på Musica Humanas hjemmeside.

  9. Behandling af hydatidose med albendazol

    DEFF Research Database (Denmark)

    Magnussen, P; Gelletlie, R; Bygbjerg, Ib Christian

    1989-01-01

    Eight patients with hydatidosis treated with albendazol in daily doses of 10 mg/kg daily in courses of 28 days (4-6 courses) were analysed. The patients came from Morocco, Spain, Turkey and Yugoslavia. Seven patients had a cyst (or cysts) in the liver and one had also cysts in the kidneys. One...

  10. Onkologisk behandling af meningeal carcinomatose

    DEFF Research Database (Denmark)

    Sulim, S.; Høyer, Morten

    2005-01-01

    Meningeal carcinomatosis (MC) occurs in 5-8% of cancer patients. In the       majority of cases, MC appears in patients with advanced disease. The       increase in incidence is probably caused by improved survival due to       improvements in systemic therapy and an increased awareness of MC among...

  11. Behandling af insulinom med alkoholsklerosering

    DEFF Research Database (Denmark)

    Schnack, Christina; Hansen, Carina Ørts; Beck-Nielsen, Henning;

    2012-01-01

    The efficacy and safety of endoscopic ultrasound (EUS)-guided alcohol ablation of an insulinoma in a patient not candidate for surgery is being evaluated. A 89 year-old male patient with insulinoma and serious cardiac disease was treated with EUS-guided alcohol ablation. The only complication...

  12. Kirurgisk behandling af cancer pancreatis

    DEFF Research Database (Denmark)

    Bergenfeldt, Magnus; Hansen, Carsten Palnaes; Mortensen, Michael Bau

    2010-01-01

    Surgery remains the only hope for cure in pancreatic cancer. The most common procedures are reviewed. Postoperative morbidity and mortality below 30% and 5%, respectively, are the standard. The benefit of extended lymph node dissection and portal-mesenteric vein resection is dubious. Selected...... patients with locally advanced cancer may be down-staged with chemo-radiotherapy and eventually resected. Endoscopic stent placement is the preferred method to relieve biliary and/or gastrointestinal obstruction. The outcome is better for patients treated at high-volume centres than at smaller hospitals....

  13. Behandling af gener efter whiplash

    DEFF Research Database (Denmark)

    Rittig-Rasmussen, Bjarne; Kongsted, Alice; Carstensen, Tina Birgitte;

    2010-01-01

    Treatment of whiplash-associated disorders starts with a thorough clinical examination, which may be repeated after 1-3 weeks. For optimal results it is essential that the patient receives clear information about the condition and that any pain is treated effectively with analgesics. Risk factors...

  14. Udredning og behandling af reflekssynkoper

    DEFF Research Database (Denmark)

    Mehlsen, Jesper; Mehlsen, Anne-Birgitte

    2008-01-01

    Syncope is associated with considerable costs to society as well as to the patient. Syncope may arise on a neurological, cardiac, or neurovascular background. Cardiac and neurological causes are evaluated by standard methods. Neurovascular syncope is diagnosed by tilt table testing and carotid ma...... massage. The treatment of neurological or cardiac syncope aims at the underlying cause, whereas the treatment of neurovascular syncope consists of information and instruction in reasonable precautions. In persisting cases, medical treatment or pacemaker implantation may be necessary....

  15. Eksperimentel bakteriofagterapi til behandling af kronisk Pseudomonas aeruginosaotitis hos hund

    DEFF Research Database (Denmark)

    Moodley, Arshnee; Mølgaard, Jesper

    2016-01-01

    Vi beskriver en case med anvendelsen af bakteriofager til behandling af kronisk otitis forårsaget af multiresistente Pseudomonas aeruginosa som en sidste behandlingsmulighed før aflivning. Trods gentagne behandlinger, både topikalt og systemisk, med op til seks forskellige antibiotika over en...

  16. Diagnose og behandling af binyrebarkkarcinom

    DEFF Research Database (Denmark)

    Abildgaard, Julie; Pappot, Helle; Petersen, Peter Meidahl;

    2013-01-01

    Adrenocortical carcinomas (ACC) are rare tumours responsible for only 0.02% of the total number of malignant diseases. However the ACC are aggressive with a mean fiveyears survival of 20-50% and are often associated with increased production of adrenocortical hormones. The effect of the treatment...... is controversial and often based on small retrospective series or expert opinions. Centralization, international attention and collaboration in the treatment of ACC are mandatory. Randomized clinical trials are needed to determine the best treatment strategy in order to increase survival in patients with ACC....

  17. Orale senfølger af behandling for hoved-halscancer

    DEFF Research Database (Denmark)

    Assaad, Hala; Dynesen, Anja Weirsøe; Thisted, Lise Bjerrum;

    2014-01-01

    Forebyggelse af orale senfølger af behandling for hoved-hals-cancer er vigtig for orale funktioner og livskvalitet Patienter, der er strålebehandlet for hovedhals-cancer, oplever betydelige senfølger i mundhulen; herunder xerostomi og hyposalivation, oral candidose, ubehag og smerte fra...... orale senfølger....

  18. Udredning og behandling af osteoporose hos patienter med kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Brask-Lindemann, Dorte; Vestbo, Jørgen;

    2012-01-01

    Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease.......Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease....

  19. Behandling af højt blodtryk hos patienter med akut apopleksi

    DEFF Research Database (Denmark)

    Olsen, T S; Jørgensen, H S; Garde, E;

    1995-01-01

    The study was performed to investigate how often reduction of high blood pressure (> or = 220 mmHg systolic and or > or = 120 mmHg diastolic) was attempted in patients with acute stroke or transient ischemic attacks (TIA). Of 1351 consecutive patients with acute stroke or TIA 119 had high blood...

  20. Et Patientperspektivistisk Studie i Brug af Alternativ Behandling hos Danske Patienter med Diabetes

    DEFF Research Database (Denmark)

    Gerbild, Helle Nygaard

    2008-01-01

    theory. The data originate from an explorative study based on semi-structured individual in-depth interviews with ten diabetic using CAM. The selection of patients for the interviews was based on several strategies. Results: In order to understand the patients’ experiences and positions of CAM......Background and objectives: There have not earlier been studies focusing on experiences of Danish diabetic patients using Complementary and Alternative Medicine (CAM) – considered from the patients’ point of view. The existing studies mostly based on quantitative methods of patients with diabetes...... prevalence in use of CAM, which is generally rather low, especially the CAM used specifically for diabetes. The objective of this paper is to develop concepts to understand patients having experiences and positions of diabetes in their use of CAM. Methods: This qualitative study its inspiration from grounded...

  1. Behandling af svær anæmi hos patienter, der afviser blodtransfusion

    DEFF Research Database (Denmark)

    Lorentzen, Kristian; Kjær, Bjarne; Olsen, Karsten Skovgaard

    2014-01-01

    In situations involving serious bleeding and anaemia, a refusal of blood transfusion puts the clinician in an ethical and medical dilemma, as standard treatment is not an option, and the patient risks dying of a potentially reversible cause. This status article describes methods of treatment unde...... the concept of "bloodless medicine", where surgical and supportive techniques are used to manage and treat severe anaemia.......In situations involving serious bleeding and anaemia, a refusal of blood transfusion puts the clinician in an ethical and medical dilemma, as standard treatment is not an option, and the patient risks dying of a potentially reversible cause. This status article describes methods of treatment under...

  2. Udredning og behandling af osteoporose hos patienter med prostatacancer uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Langdahl, Bente Lomholt; Eiken, Frederik L;

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostate cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of non...

  3. Organtransplanterede patienter har behov for intensiv kontrol og behandling af hudcancer

    DEFF Research Database (Denmark)

    Togsverd-Bo, Katrine; Sørensen, Søren Schwartz; Hædersdal, Merete

    2013-01-01

    The risk of non-melanoma skin cancer (NMSC) and in particular squamous cell carcinoma is significantly increased in organ transplant recipients due to long-term treatment with immunosuppressives. Dermatologic management in the form of a multidisciplinary approach, including patient education, skin...

  4. Behandling af digital dermatitis på KFC

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    På Kvægbrugets Forsøgscenter blev de rutinemæssige klovbade i maj 2007 erstattet med månedlige tjek af klove i beskærerboks og behandling af klovlidelser, herunder især Digital Dermatitis. Behandlingseffekten har været høj med 90 % helbredte efter en måned. Udgivelsesdato: april 2008......På Kvægbrugets Forsøgscenter blev de rutinemæssige klovbade i maj 2007 erstattet med månedlige tjek af klove i beskærerboks og behandling af klovlidelser, herunder især Digital Dermatitis. Behandlingseffekten har været høj med 90 % helbredte efter en måned. Udgivelsesdato: april 2008...

  5. Noninvasiv behandling af slid og erosion

    DEFF Research Database (Denmark)

    Pallesen, Ulla; Dijken, Jan van

    2012-01-01

    Slid og erosion af tænder synes i dag at være et voksende problem for mange patienter. I de fleste tilfælde kan tandlægens tidlige diagnostik føre til, at forebyggende tiltag iværksættes i tide, så fortsatte skader ophører, eller progressionen begrænses. Desværre er det ikke altid muligt, og hvis...

  6. Fysisk rehabilitering i forbindelse med behandling af hæmatologiske sygdomme

    DEFF Research Database (Denmark)

    Høgdal, Nina; Bartels, Frederik Reith; Smith, Nicholas Simon;

    2015-01-01

    I denne statusartikel vurderes det, hvorvidt det eksisterende fysioterapeutiske træningstilbud under behandling af maligne sygdomme med højdosis kemoterapi og perifer stamcellestøtte (HD-ASCT) lever op til anbefalingerne i Kræftplan III. Alle seks hospitaler i Danmark, som behandler patienter med...... HDASCT, indgår i undersøgelsen. Resultatet af undersøgelsen peger på, at fysisk aktivitet ikke er højt prioriteret på landets hospitaler. Fysioterapinormeringen er sparsom, så daglig prioritering er nødvendig, og enkelte steder er der under indlæggelse ventetid på opstart af fysioterapi...

  7. Gruppebaseret behandling af BED - et faseopdelt behandlingstilbud

    DEFF Research Database (Denmark)

    Laust, Jakob; Lau, Marianne Engelbrecht; Waaddegaard, Mette

    2015-01-01

    konsekvenser. BED blev i 2013 optaget i DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) som en selvstændig diagnose og BED forventes medtaget i den forestående revision af det internationale diagnose system, ICD-11. Sundhedsstyrelsen gav på denne baggrund satspuljemidler til erfaringsopsamling...

  8. Nationale domstoles behandling af internationale normkonflikter

    DEFF Research Database (Denmark)

    Kjeldgaard-Pedersen, Astrid

    2013-01-01

    Med sin dom af 12. september 2012 i sagen Nada v. Switzerland har Den Europæiske Menneskerettighedsdomstol (EMD) givet ny næring til debatten om, hvordan konflikter mellem staters forpligtelser ifølge Den Europæiske Menneskerettighedskonvention (EMRK) og deres forpligtelser efter bindende...

  9. Udvikling af medicinsk behandling mod bipolar lidelse

    DEFF Research Database (Denmark)

    Ellegaard, Pernille Kempel

    2015-01-01

    Selvom Esbjerg ligger i vandkants Danmark, er det den Psykiatriske Forskningsenhed i denne by, der er primus motor for et stort forsøg blandt mennesker, der lider af bipolar lidelse. Forsøget hedder ”NACOS”, og er et medicinsk forsøg til mennesker, der befinder sig i den depressive fase.......Selvom Esbjerg ligger i vandkants Danmark, er det den Psykiatriske Forskningsenhed i denne by, der er primus motor for et stort forsøg blandt mennesker, der lider af bipolar lidelse. Forsøget hedder ”NACOS”, og er et medicinsk forsøg til mennesker, der befinder sig i den depressive fase....

  10. Traditionel og alternativ behandling af sklerosepatienter

    DEFF Research Database (Denmark)

    Stenager, E N; Stenager, Egon; Knudsen, L;

    1989-01-01

    The medicine consumption and the employment of alternative treatment were investigated in a material of 117 patients with disseminated sclerosis (DS) considered to be a representative sample of the patients with DS in the County of Funen. This investigation revealed that the preparations most...... commonly employed to modify the disease among patients with disseminated sclerosis were: spasmolytics, agents to counteract neurogenic bladder symptoms, benzodiazepine and analgesics. The consumption of medicine increased with increasing handicap. Employment of psychopharmaca was commonest in patients...

  11. Neurointensiv behandling af svaere traumatiske hjerneskader

    DEFF Research Database (Denmark)

    Welling, Karen-Lise Kobberø; Eskesen, Vagn; Romner, Bertil;

    2010-01-01

    We present a Danish algorithm for the neurointensive care of patients with severe traumatic brain injury. The primary goal is to avoid cerebral ischaemia and hypoxia and secondarily brain injury. Patient evaluation by a neurosurgeon is mandatory, and decision-making concerning extended cerebral m...... monitoring should take place immediately. Treatment aiming at diminishing increased intracranial pressure should be initiated early. Early critical care management of patients with severe traumatic brain injury should be performed in a teamwork comprising various specialties....

  12. Lenalidomid til behandling af transfusionskraevende myelodysplastisk syndrom

    DEFF Research Database (Denmark)

    Risum, Malene; Dufva, I.H.

    2010-01-01

    Lenalidomide is the first drug to induce transfusion independence and cytogenetic remission in patients with myelodysplastic syndrome (MDS) with deletion 5q and low or intermediate risk score. Transfusion independence can be obtained within five weeks. Three out of four patients also obtain...

  13. Flumazenil til behandling af hepatisk encefalopati

    DEFF Research Database (Denmark)

    Elkjaer, J M; Jensen, T U; Emborg, J

    2000-01-01

    Hepatic encephalopathy (HE) is the neuropsychiatric syndrome that occurs as a complication to liver failure in patients with acute or chronic liver disease. Mental status in this syndrome can range from subtle deficits to coma, with respiratory insufficiency and aspiration to the lungs. The morta......Hepatic encephalopathy (HE) is the neuropsychiatric syndrome that occurs as a complication to liver failure in patients with acute or chronic liver disease. Mental status in this syndrome can range from subtle deficits to coma, with respiratory insufficiency and aspiration to the lungs....... Transient improvement of the condition is seen in a subgroup of patients after administration of flumazenil, a specific benzodiazepine antagonist. The group of patients with a positive response to flumazenil therapy may have a better prognosis. Flumazenil may be used in patients in the pretransplantation...

  14. Udredning og behandling af osteoporotiske hoftefrakturer

    DEFF Research Database (Denmark)

    Eiken, Pia A; Abrahamsen, Bo

    2010-01-01

    INTRODUCTION: Osteoporosis is a major cause of low-energy hip fractures. Although there are pharmacologic agents available for both prevention and treatment, less than 10% of hip fracture cases initiate anti-osteoporotic treatment. MATERIAL AND METHODS: In 1995 and 2008, questionnaires were sent......% in 2008. In 2008, 48% of the departments informed the GPs that their patient with a low-energy fracture may have osteoporosis and that further evaluation and treatment may be needed. CONCLUSION: Medical treatment after fractures was more widespread in 2008 than in 1995. About half of the Danish...... to all Danish orthopaedic surgery departments treating patients with low-energy hip fractures, asking them to explain a) whether patients with osteoporosis are identified, b) whether the patients identified are treated for osteoporosis, and c) whether physicians need more information about osteoporosis...

  15. Biologisk behandling af psoriasis og psoriasisartritis

    DEFF Research Database (Denmark)

    Kragballe, Knud; Deleuran, Bent

    2008-01-01

    Psoriasis is an immune-mediated inflammatory skin disease which may be associated with psoriatic arthritis. Biological therapy is indicated in patients who do not respond to, or are intolerant to, or have contraindication against traditional therapy. TNFalpha antagonists are used for both skin...... and joint disease, while efalizumab, which targets T lymphocytes, is only indicated for the skin disease. Registration of the treated patients in quality databases is an essential instrument in the surveillance of beneficial and adverse events during biological therapy. Udgivelsesdato: 2008-Jun-9...

  16. Operativ behandling af thoracic outlet syndrome

    DEFF Research Database (Denmark)

    Birkeland, Peter; Stiasny, Jerzy

    2012-01-01

    of the brachial plexus. At surgery, we found and severed a fibrous band that compressed the inferior trunk. Postoperatively, the pain subsided and fine hand movements improved. One patient had no cervical rib, however, in the two other cases we found rudimentary cervical ribs. Magnetic resonance imaging......We present three cases with longstanding true neurogenic thoracic outlet syndrome. All patients had aching pain in the shoulder, arm and ulnar border of the hand. On examination, we found atrophy of the hand muscles. Electromyography revealed signs of compromised function of the inferior trunk...

  17. Behandling af diabetes mellitus med biologiske laegemidler

    DEFF Research Database (Denmark)

    Larsen, Claus Morten; Mandrup-Poulsen, Thomas

    2008-01-01

    Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps of the patho......Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps...... of the pathogenesis of type 1 and type 2 diabetes which are targeted by biologic therapeutics and reviews the treatment results. Udgivelsesdato: 2008-Jun-9...

  18. Behandling af Tourettes syndrom med aripiprazol

    DEFF Research Database (Denmark)

    Stenstrøm, Anne Dorte; Sindø, Ingrid

    2008-01-01

    , due to TS. The initial treatment consisted of pimozide and risperidone, both of which had an unsatisfactorily efficacy on tics and side effects in the form of weight gain and sedation. The patient is now treated with aripiprazole and there is a marked reduction of tics and no side effects...

  19. Kirurgisk behandling af levermetastaser og levercancer

    DEFF Research Database (Denmark)

    Wojdemann, M.; Burcharth, F.; Rokkjaer, M.

    2008-01-01

    Hepatic resection is the golden standard in treatment of tumours from primary liver cancer and colorectal liver metastases, but is appropriate for a variety of other benign and malignant tumours in the liver. The selection of patients and criteria are discussed. Curative liver surgery...

  20. Udredning og behandling af morbus Osler

    DEFF Research Database (Denmark)

    Kjeldsen, Anette Drøhse; Andersen, Poul Erik; Tørring, Pernille Mathiesen

    2011-01-01

    such as pulmonary arteriovenous malformations (PAVM), cerebral arteriovenous malformations (CAVM) and gastrointestinal bleeding. Collaboration between various medical specialties is essential in order to provide an up-to-date treatment and thorough work-up in the individual patient. Disregard of symptoms may result...

  1. Biofarmaka til behandling af reumatoid artritis

    DEFF Research Database (Denmark)

    Baslund, Bo; Bendtzen, Klaus

    2008-01-01

    The current status on the use of biopharmaceuticals in the treatment of rheumatoid arthritis is reviewed. Blocking of TNF-alpha, co-stimulation of CD28+ T-cells and depletion of CD20+ B-cells are all effective ways to diminish inflammation and joint damage. However, not all patients react to thes...

  2. Behandling af ideopatisk hypereosinofilt syndrom med imatinib

    DEFF Research Database (Denmark)

    Sørensen, Anne Louise; Larsen, Herdis

    2008-01-01

    We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded...

  3. Elektrokemoterapi til behandling af kutane metastaser

    DEFF Research Database (Denmark)

    Falk, Hanne; Matthiessen, Louise Wichmann; Dahlstrøm, Karin;

    2015-01-01

    effect by at least 300-fold. Electrochemotherapy is an efficient, once only treatment for cutaneous metastases with an objective response of 62-99%. Electrochemotherapy can reduce discomfort such as ulceration, oozing, bleeding and pain. Adverse events depend on the size of treatment area, but are very......Cutaneous metastases occur in up to 9% of all patients with cancer and may cause discomfort and stigmatization. Electrochemotherapy is a local treatment using electric pulses to permeabilize cell membranes, enabling chemotherapy, such as bleomycin, to enter the cells and increase the cytotoxic...

  4. Behandling af peritonsillær absces

    DEFF Research Database (Denmark)

    Anthonsen, Kristian; Trolle, Waldemar

    2012-01-01

    Peritonsillar abscess (PTA) is associated with high morbidity and can cause serious and life-threatening complications. In Denmark, the most commonly isolated bacteria are Fusobacterium necrophorum and Streptococcus pyogenes gr. A. The incidence of PTA in Denmark is 41/100,000/year, the highest...... incidence ever reported for PTA. There is no definite consensus on the treatment. We recommend most patients treated with puncture and antibiotics as outpatients, and if necessary acute tonsillectomy instead of interval tonsillectomy. Steroids may be of value....

  5. Forebyggelse af infektioner hos patienter, der har kronisk inflammatorisk tarmsygdom og er i behandling med TNF-hæmmere

    DEFF Research Database (Denmark)

    Risager Christensen, Katrine; Steenholdt, Casper

    2014-01-01

    suppression of the immune system. National and international guidelines recommend screening and vaccination for selected infectious agents prior to anti-TNF initiation as well as during ongoing anti-TNF therapy. This review focuses on current available recommendations and discusses physicians’ and patients...

  6. Behov for bedre organisering af udredning og behandling af hoste

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli

    2013-01-01

    Cough is frequently a reason for seeing a doctor. Cough has a wide range of causes and the diagnosis can be difficult to make. Cough is often benign and self-limiting but can also be the first sign of malignancy. Especially chronic cough reduces the patients' quality of life. The purpose of this ......Cough is frequently a reason for seeing a doctor. Cough has a wide range of causes and the diagnosis can be difficult to make. Cough is often benign and self-limiting but can also be the first sign of malignancy. Especially chronic cough reduces the patients' quality of life. The purpose...

  7. Behandling af epilepsi ved stimulation af nervus vagus

    DEFF Research Database (Denmark)

    Hansen, Christian Pilebaek; Sidenius, Per Christian; Gyllenborg, Jesper

    2010-01-01

    epilepsy surgery is not feasible, vagus nerve stimulation (VNS) should be offered. VNS seems to have an effect in all epilepsy syndromes and seizure types. VNS is generally well-tolerated, and may even improve mood and quality of life. Many more epilepsy patients in Denmark should be offered VNS....

  8. Forebyggelse og behandling af osteoporose i forbindelse med behandling af ikke-metastaserende prostatacancer

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Langdahl, Bente Lomholt; Eiken, Frederik L;

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostatae cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of non...

  9. Non-invasiv behandling af slid og erosion

    DEFF Research Database (Denmark)

    Pallesen, Ulla; van Dijken, Jan WV

    2011-01-01

    Slid og erosion af tænder synes i dag at være et voksende problem for mange patienter. I de fleste tilfælde kan tandlægens tidlige diagnostik føre til, at forebyggende tiltag iværksættes i tide, så fortsatte skader ophører eller progressionen begrænses. Desværre er det ikke altid muligt og hvis s...

  10. Mentaliseringsbaseret behandling og musikterapi

    DEFF Research Database (Denmark)

    Hannibal, Niels

    2013-01-01

    Denne artikel behandler spørgsmålet, om mentaliseringsbaseret terapi er en metode der medfører et skift i terapeutisk forholdemåde for analytisk orienterede musikterapeuter i arbejde med patienter med personlighedsforstyrrelse. Artiklen skal ses om en del af den teoretiske integrationer af MBT i...

  11. Dilemmaer i musikterapeutisk behandling af en traumatiseret flygtning med musikerbaggrund

    Directory of Open Access Journals (Sweden)

    Bolette Daniels Beck

    2016-12-01

    Full Text Available Denne artikel præsenterer et single case-studie af et receptivt musikterapiforløb med en 55-årig syrisk flygtning, som har været udsat for fængsling og tortur på grund af sine aktiviteter som protestsanger og musiker. Der beskrives problemstillinger og dilemmaer relateret til at anvende musik, der både kan trigge traumer, men også vække indre ressourcer. Kortlægning af patientens forskellige personlighedsdele og musikkens evne til integration af dem vil blive belyst gennem teorien om strukturel dissociation.

  12. Alternativ behandling og kræft

    DEFF Research Database (Denmark)

    Lunde, Anita; Johannessen, Helle

    2010-01-01

    Baggrund: Interessen for komplementær og alternativ behandling (KAB) er stadig stigende, og der kan dokumenteres et større forbrug af KAB blandt kræftpatienter. Patienter anvender primært KAB som supplement til deres konventionelle behandling, og mange så gerne KAB som en integreret praksis. Fler...

  13. GIM-behandling af en traumatiseret flygtning med PTSD – med fokus på traumebearbejdning

    Directory of Open Access Journals (Sweden)

    Torben Moe

    2016-12-01

    Full Text Available Artiklen omhandler en case med fokus på direkte traumebehandling i traumefokuseret Guided Imagery and Music (GIM. Patienten deltog i et mixed methods feasibility-pilotprojekt vedrørende behandling af traumatiserede flygtninge, som er beskrevet i artiklen Feasibility of trauma-focused Guided Imagery and Music with adult refugees diagnosed with PTSD – a pilot study. Patienten modtog 16 sessioner over en periode på ca. 6 måneder. I artiklen gives eksempler på traumefokuserede interventioner og eksempler på patientens kommentarer, oplevelser, refleksioner og udbytte af behandlingen. Behandlingstilgangen i konteksten med traumatiserede flygtninge er en ny variation inden for spektret af GIM-terapi, og beskrivelsen af behandlingsforløbet understøttes af teoretisk forståelse af processen. Resultater for pilotstudiet viser, at patienten fik signifikant udbytte af terapien. Dette bliver understøttet af patientens egne udtalelser i evalueringen af forløbet samt ud fra data fra de spørgeskemaer, der blev anvendt i undersøgelsen. Patienten har efter GIM-forløbet en score på Harwards Trauma Questionaire (HTQ, som ligger under cut-off for diagnosen PTSD og scorer markant højere på WHO-5 livsstil-skemaet.

  14. Private personers behandling af fortrolige oplysninger fra offentlige myndigheder

    DEFF Research Database (Denmark)

    Bønsing, Sten

    2014-01-01

    Denne artikel undersøger, i hvilket omfang den private borger, der kommer i besiddelse af fortrolige oplysninger fra forvaltningsmyndigheder, er begrænset i anvendelsen og videregivelsen heraf. Der gælder ikke et samlet regelsæt, der afgør spørgsmålet, men en række regler i straffeloven og person...... persondataloven kan bringes i anvendelse. Samlet set vil der ofte gælde en form for tavshedspligt for den private, men den endelige konklusion afhænger af de konkrete oplysningers karakter, og hvordan oplysningerne håndteres af borgeren....

  15. Behandling af peritoneal karcinose med laparoskopisk intraperitoneal kemoterapi under tryk

    DEFF Research Database (Denmark)

    Graversen, Martin; Pfeiffer, Per; Mortensen, Michael Bau

    2016-01-01

    Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment option in patients with peritoneal carcinomatosis (PC). PIPAC has proven efficacious in the treatment of PC from ovarian, colon and gastric cancer. PIPAC has a favourable profile regarding safety for patients and occupati......Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment option in patients with peritoneal carcinomatosis (PC). PIPAC has proven efficacious in the treatment of PC from ovarian, colon and gastric cancer. PIPAC has a favourable profile regarding safety for patients...

  16. Muskuloskeletal behandling af 11-årig med artrogrypose

    DEFF Research Database (Denmark)

    Thomsen, Maria Morandi; Thomsen, Stig Aaberg; Due, Pernille

    2010-01-01

    A two-year-old patient was diagnosed with arthrogryposis because of inflected knees (15-20 degrees) and stiff hamstrings. All joints and reflexes were normal. Activities were described as age-appropriate, but the patient walked with inflected knees and increased lumbal lordosis. Physiotherapy...... and botox did not improve the condition. Because of pain and hampered activities, the patient - now aged 11 years - was treated with musculoskeletal medicine. After treatment the patient could walk normally without pain and stand with stretched knees....

  17. Salmonella typhi--tid til aendring af den empiriske behandling

    DEFF Research Database (Denmark)

    Gade, Christina; Engberg, Jørgen; Weis, Nina

    2008-01-01

    In the present case series report we describe seven recent cases of typhoid fever. All the patients were travellers returning from Pakistan, where typhoid is endemic. Salmonella typhi isolated from the patients by blood culture were reported as intermediary susceptible to fluoroquinolones in six...

  18. At udholde forandringer i hverdagslivet – patienters oplevelse af at være i behandling for endetarmskræft

    DEFF Research Database (Denmark)

    Hansen, Birgitte Knygle; Winther, Bodil; Norlyk, Annelise

    2015-01-01

    treatment for colonic cancer. Ten patients participated in the study. Data were collected through semi-structured interviews and analysed using the guidelines for meaning interpretation given by Kvale and Brinkmann. The analysis led to one dominating theme: endurance and four subthemes: coping with bodily...

  19. Præhospital behandling af svært tilskadekomne patienter med fokus på damage control-kirurgi

    DEFF Research Database (Denmark)

    Sørensen, Anne Marie; Larsen, Claus Falck; Steinmetz, Jacob

    2011-01-01

    The majority of patients undergoing damage control surgery initially receive prehospital treatment. Bleeding causes 40% of trauma deaths, half of which happen in the prehospital setting. Future research and improved treatment before hospital admission should focus on control of the bleeding, avoi...

  20. Farmakologisk behandling af mild ukompliceret hypertension i almen praksis

    DEFF Research Database (Denmark)

    Paulsen, Maja Skov; Christensen, Bo; Søndergaard, Jens

    2013-01-01

    Hypertension is an important risk factor for cardiovascular disease. In Denmark, patients with hypertension are primarily managed in primary care. A recent Cochrane review concluded that pharmacotherapy of patients with mild hypertension (systolic blood pressure 140-159 mmHg; diastolic blood...... pressure 90-99 mmHg; no diabetes or cardiovascular disease) did not reduce mortality or morbidity. The evidence for pharmacotherapy in patients having mild/uncomplicated hypertension is weak. However, current Danish guidelines have taken this into consideration in their recommendations of pharmacotherapy...

  1. Gener efter behandling af almindeligt forekommende akutte øjenlidelser

    DEFF Research Database (Denmark)

    Krogsgaard, M R; Danborg, L; Jensen, P;

    1990-01-01

    and 75% within 48 hours. 10% had symptoms for more than a week. Cases of infectious conjunctivitis and trauma to the eye (without intrabulbar lesion) had the highest risk of developing symptoms after the consultation. The lowest incidence of complaints was seen among patients in whom a foreign body...... was removed from the cornea or conjunctiva. The longest duration of symptoms was seen among patients with infectious conjunctivitis. Cases with a foreign body on the cornea or conjunctiva or trauma to the eye (without intrabulbar lesion) had a slightly longer duration of the symptoms when a corneal tear......The aim of the study was to determine the duration of symptoms in patients treated in the emergency room at Glostrup Hospital for acute eye-trouble. Nine common diagnoses were selected for the study. All patients seen during a 2 1/2 month period were asked to complete a questionnaire one week after...

  2. Trombosering af mekanisk mitralklapprotese under behandling med dabigatran

    DEFF Research Database (Denmark)

    Thomsen, Jakob Hartvig; Kjaergaard, Jesper; Saust, Laura Trolle;

    2014-01-01

    Dabigatran has been approved for prevention of thromboembolic complications in nonvalvular atrial fibrillation. We present a case of thrombosis of a mechanical prosthetic mitral valve during anticoagulation with dabigatran, switched from warfarin. The patient presented with cardiogenic shock...

  3. Behandling af metforminassocieret laktatacidose med hæmodialyse

    DEFF Research Database (Denmark)

    Schousboe, K.; Rasmussen, K.; El Fassi, D.;

    2012-01-01

    Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two...... of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis....

  4. Linezolid som behandling af infektiøs endokarditis

    DEFF Research Database (Denmark)

    Lauridsen, Trine Kiilerich; Arpi, Magnus; Bruun, Niels Eske

    2010-01-01

    In Denmark enterococci causes 15 to 20% of all endocarditis (IE) cases. The development of multi-resistant bacterial strains has increased the need for new antibiotics. Linezolid is an alternative to conventional treatment of infections with gram positive cocci. In this case report linezolid was ...... was used to treat IE in a patient, who was allergic to penicillin and where conventional treatment caused development of acute renal failure. No side effects were observed and the patient responded well to the treatment....

  5. Endoventrikulaer venstre ventrikel-rekonstruktion til behandling af hjerteinsufficiens

    DEFF Research Database (Denmark)

    Funder, Jonas Amstrup; Klaaborg, Kaj-Erik; Egeblad, Henrik;

    2009-01-01

    ventricular restoration was performed in 26 patients (23 males) with a median age of 64 years (47-74 years). Twenty-one of the patients were in New York Heart Association (NYHA) class III-IV. The median preoperative left ventricular ejection fraction was 27% (13-38%). We collected both pre- and postoperative...... had increased to 35% (18-53%) (p class I-II (p

  6. Nyrepåvirkning ved behandling af hjertesvigt

    DEFF Research Database (Denmark)

    Rasmussen, Zhiying Zhang; Barfod, Toke; Klit, Jakob

    2009-01-01

    The case of a 66-year-old male with heart failure and cardiorenal syndrome is presented. The patient had normal renal function before intensive treatment with diuretics and ACE inhibitor. Shortly after the ACE inhibitor was stopped and diuretics were either stopped or reduced in dosage, his renal...

  7. Stor forskel i behandling af depression mellem psykiatriske afdelinger

    DEFF Research Database (Denmark)

    2010-01-01

    A large proportion of patients admitted to psychological departments and wards suffer from depression. Knowledge is limited about the clinical aspects and treatment of depression at admission and discharge, as well as about the differences between psychiatric hospitals. The purpose of this study...

  8. Utilfredsstillende langtidsresultater efter konservativ behandling af patellofemoralt smertesyndrom

    DEFF Research Database (Denmark)

    Rathleff, Michael Skovdal; Rasmussen, Sten; Olesen, Jens Lykkegaard

    2012-01-01

    This review overviews the long-term prognosis of conservatively treated patients with patellofemoral pain syndrome (PFPS). Median values of the 16 included studies show that 29% of soldiers, 27.8% of sports active and 24,7% of the general public will become pain free after they are diagnosed...

  9. Transanal minimally invasive surgery til behandling af lav rectumcancer

    DEFF Research Database (Denmark)

    Levic, Katarina; Bulut, Orhan

    2014-01-01

    Laparoscopic total mesorectal excision (LTME) has become the standard surgical treatment of rectal cancer. There is however technical challenges when operating patients with a narrow pelvis with tumours located in distal or middle part of the rectum. We describe a case of a 71-year-old male...

  10. Transanal minimal invasiv kirurgi til behandling af lav rectumcancer

    DEFF Research Database (Denmark)

    Levic, Katarina; Bulut, Orhan

    2014-01-01

    Laparoscopic total mesorectal excision (LTME) has become the standard surgical treatment of rectal cancer. There is however technical challenges when operating patients with a narrow pelvis with tumours located in distal or middle part of the rectum. We describe a case of a 71-year-old male...

  11. Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    DEFF Research Database (Denmark)

    Fassi, Daniel El; Nielsen, Claus Henrik; Bendtzen, Klaus

    2006-01-01

    Rituximab (RTX) is a murine/human monoclonal antibody to CD20, a protein expressed almost exclusively on human B-lymphocytes. RTX induces rapid and marked B-cell depletion with beneficial clinical effects in 1/3 to 1/2 of rheumatoid arthritis patients. Treatment is given as two iv. infusions with...

  12. Bedre prognose af cystinose ved behandling med cysteamin og nyretransplantation

    DEFF Research Database (Denmark)

    Oczachowska-Kulik, Anna Ewa; Lund, Allan; Skovby, Flemming

    2011-01-01

    Cystinosis is a rare, autosomal recessive disease with cystine deposits in different tissues. First signs come from kidneys and eyes, but during progression of the disease other organs can also be affected. Previously, patients with cystinosis had a very poor prognosis, but it is now considerably...

  13. Måling af nyrefunktion under cytostatisk behandling

    DEFF Research Database (Denmark)

    Hartlev, Louise Brøndt; Bøje, Charlotte Rotbøl; Bluhme, Henrik;

    2008-01-01

    INTRODUCTION: Some cytostatics, used in the treatment of cancer, are excreted by the kidneys and may be nephrotoxic. The glomerular filtration rate (GFR) represents a method for reliable assessement of the 51Cr-EDTA plasma clearance before and during treatment with nephrotoxic drugs. The aim...... of this retrospective study was to evaluate whether this method could be replaced by a more simplified GFR estimate calculated from the creatinine plasma concentration. MATERIALS AND METHODS: We included all patients who had had at least four GFR measurements in 2005 as part of their nephrotoxic cytostatic treatment....... The estimated GFR (eGFR) was calculated from sex, age and weight, according to the Cockcroft formula. RESULTS: Forty-eight patients with a mean age of 47 years were included. 51Cr-EDTA plasma clearance and eGFR showed a poor correlation (r(2) = 0,678). On average, GFR decreased from 95 ml/min to 80 ml/min from...

  14. Diagnostik og behandling af paroksystisk supraventrikulær takykardi

    DEFF Research Database (Denmark)

    Rujic, Dragana; Sundbøll, Jens; Tofig, Bawer Jalal;

    2016-01-01

    The paroxysmal supraventricular tachycardias (SVT) are commonly encountered arrhythmias and include atrioventricular nodal re-entrant tachycardia, atrioventricular reciprocating tachycardia, and focal atrial tachycardia. These tachycardias share several clinical features as well as similar...... management strategies. The probable mechanism of paroxysmal SVT can often be diagnosed from the clinical findings and a 12-lead ECG. This review describes the initial evaluation and treatment of patients with paroxysmal SVT, including distinctive features from the most important differential diagnoses....

  15. Biologisk behandling af neuroendokrine tumorer i mave-tarm-kanalen

    DEFF Research Database (Denmark)

    Hansen, Carsten Palnaes; Knigge, Ulrich

    2008-01-01

    Biotherapy of hormonal symptoms and tumour growth is a mainstay in the therapy of metastatic neuroendocrine tumours of the gastrointestinal tract and pancreas. Symptomatic relief can be achieved by somatostatin analogues and interferon, either alone or in combination. The effect on tumour growth...... is less convincing although a stabilization of disease is recorded in almost 50% of patients. Interferon treatment should mainly be considered for tumours with a low proliferation index....

  16. Diagnostik og behandling af næsefraktur hos voksne

    DEFF Research Database (Denmark)

    Sjöstedt, Sannia; Larsen, Christian Grønhøj; Bilde, Anders;

    2016-01-01

    The risk of complications warrants treatment of most dislocated nasal fractures. Other injuries including other facial fractures and septal haematoma must be treated if present at the initial presentation. The usual treatment for a simple nasal fracture is closed reduction in local anaesthesia...... after five to seven days. Complicated cases require open reduction in general anaesthesia. Later revision of the deviated nose may become necessary in patients suffering from complications such as persistent nasal stenosis and/or deformity....

  17. Filetlap til behandling af livstruende tryksår

    DEFF Research Database (Denmark)

    Gunnarsson, Gudjon Leifur; Høimyr, Hilde; Rossi, Paolo Emilio

    2014-01-01

    A 71-year-old multi-morbid, paraplegic male with five pressure ulcers and a left-sided open trochanter fracture with chronic osteomyelitis was admitted to hospital. His condition required exarticulation of the left hip joint. A radical wound revision and a pedicled lower extremity fillet flap...... reconstruction of the defect was performed. The patient made uneventful recovery to normal activity within six weeks and had a stable result after one year follow-up. The case is a reminder of the importance of early intervention and preventive management of pressure ulcers and elaborates the benefits...... of interdisciplinary team efforts in the treatment of advanced ulcers....

  18. Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    DEFF Research Database (Denmark)

    El Fassi, Daniel; Nielsen, Claus Henrik; Bendtzen, Klaus

    2006-01-01

    Rituximab (RTX) is a murine/human monoclonal antibody to CD20, a protein expressed almost exclusively on human B-lymphocytes. RTX induces rapid and marked B-cell depletion with beneficial clinical effects in 1/3 to 1/2 of rheumatoid arthritis patients. Treatment is given as two iv. infusions...... with a two-week interval and in combination with methotrexate. Mild to moderate side-effects are frequent, particularly during the first infusion, but long-term side-effects are generally rare, although pulmonary events and reactivation of viral infections of the liver is of concern....

  19. Er danske sygeplejersker "klædt på" til mødet med patienter, som anvender alternativ behandling

    DEFF Research Database (Denmark)

    Lunde, Anita

    alternativ behandling forekommer af og til, dialogen indgår dog sjældent som et fast punkt i planlagte samtaler, ligesom langt de fleste sygeplejersker aldrig giver konkrete anbefalinger om alternativ behandling. Sygeplejersker anser alternativ behandling som et meget bredt felt, som også afspejler sig i...

  20. Forekomst, kausalitet og behandling af polyneuropati associeret til monoklonal gammopati af ukendt signifikans

    DEFF Research Database (Denmark)

    Moth Henriksen, Marie; Kolmos, Eva Brøsted; Abildgaard, Niels;

    2012-01-01

    The prevalence of polyneuropathy in patients with monoclonal gammopathy of undetermined significance (MGUS) has been reported to be 10-50%. The majority of patients have a chronic, slowly progressive, distal, symmetric and predominantly sensory polyneuropathy. A caused relationship between...

  1. Medikamentel behandling af cancerrelateret traethed--en gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Pedersen, Lise; Palshof, Torben

    2009-01-01

    and multidimensional phenomenon Apart from erythropoietin and to some degree methylphenidate, there is no evidence that pharmacologic intervention may reduce CRF. CRF has major impact on quality of life for most patients suffering from a cancer disease. It is therefore of obvious importance to increase the focus...... on CRF - both in the pharmaceutical industry and in the professional-medical environment. Udgivelsesdato: 2009-Sep...

  2. Prognostiske faktorer af betydning for den recidivfrie overlevelse efter kirurgisk behandling af hoved-hals-melanom

    DEFF Research Database (Denmark)

    Andersson, A P; Gottlieb, J; Søndergaard, K;

    1993-01-01

    The clinico-pathological and therapeutic data of 512 patients with clinical stage I invasive head and neck melanoma of the skin were re-evaluated. There were 287 females and 225 males. The median age at primary surgery was 65 years, range 18 to 96 years. The median observation period was 5 years...

  3. Gentaget selvmordsforebyggende behandling

    DEFF Research Database (Denmark)

    Lind, Bertel

    2014-01-01

    forbedringer i deres behandling, der kunne oplyse os om effekten af behandlingen på patienterne og på at reducere deres på selvmordsforsøgs rate. Metoder Den metodiske tilgang er mixed design ( Creswell 2009) med både kvantitativ og kvalitativ metode i dataindsamlingen og i analysen. Den overliggende metodiske...

  4. Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

    DEFF Research Database (Denmark)

    Olesen, Anne Estrup; Jarvig, Line; Hansen, Ole Bo;

    2007-01-01

    analgesics were prescribed for 40% of the patients while 50% of the patients were treated with paracetamol and/or NSAID. According to the medical records 79% of the patients were prescribed analgesics for breakthrough pain. 73% of the 347 patients had strong opioids prescribed for breakthrough pain....... For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment...

  5. Kirurgisk behandling af renovaskulaer hypertension forårsaget af nyrearteriestenose. En retrospektiv opgørelse

    DEFF Research Database (Denmark)

    Hensler, M K; Forrest, M; Schroeder, T V;

    1994-01-01

    months. At follow-up (median 65 months), 85% of the patients had normal blood pressure or either no, modest or considerably reduced anti-hypertensive medication. It is concluded that surgical treatment of renovascular hypertension is a safe and effective procedure.......During a 10 year period 58 patients with renovascular hypertension due to renal artery stenosis were treated surgically. A retrospective analysis of the results was carried out. No perioperative mortalities occurred. Ten percent of the patients developed hypertension again after an average of 27...

  6. Fedmekirurgi er mere effektiv end medicinsk behandling til opnåelse af remission af type 2-diabetes

    DEFF Research Database (Denmark)

    Klein, Mads; Rosenberg, Jacob; Gögenur, Ismail

    2013-01-01

    Observational studies have shown that bariatric surgery can lead to remission of diabetes mellitus type 2 (DMII), but randomized controlled trials have been lacking. Recently, randomized controlled trials comparing bariatric surgery with optimal medical treatment in patients suffering from poorly...

  7. Behandling af reumatoid artrit med anti-tumornekrosefaktor-alpha-antistof. Individuel monitorering af biotilgaengelighed og immunogenicitet-- sekundaerpublikation

    DEFF Research Database (Denmark)

    Bendtzen, Klaus; Geborek, Pierre; Svenson, Morten

    2007-01-01

    Remicade/infliximab is effective in rheumatoid arthritis (RA), but response failure is frequent. Sera from 106 RA patients were monitored using an RIA for functional infliximab and an RIA for anti-infliximab antibody (Ab). S-infliximab varied considerably, e.g. 0-22 microg/ml before the 3rd...... infusion, and 44% were Ab-positive after 6 months. Low s-infliximab was associated with Ab development and later therapeutic failure, and high Ab levels could be related to dose increases, side-effects and cessation of therapy. Pharmacological monitoring should help optimize anti-TNF therapies....

  8. Behandling af våd aldersrelateret makuladegeneration med vaskulaer endotel vaekstfaktorhaemmer. Gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Bloch, Sara Brandi; Larsen, Michael

    2009-01-01

    a direct comparison or an indirect statistical comparison between the two antiangiogenic agents. In clinical practice ranibizumab compared to pegaptanib is the drug of choice because of cost-utility analysis and the number of patients gaining visual acuity. Udgivelsesdato: 2009-Nov......This evaluation of a Cochrane-review including five clinical trials of good methodological quality indicates that the antiangiogenic therapeutic agents, pegaptanib and ranibizumab, are effective treatment strategies for neovascular Age-Related Macular Degeneration (AMD). The review does not include...

  9. Mulig forbedret behandling af kolorektal cancer med sentinel lymph node-diagnostik

    DEFF Research Database (Denmark)

    Burgdorf, Stefan K; Eriksen, Jens Ravn; Gögenür, Ismail

    2014-01-01

    Possibly improved treatment of colorectal cancer by sentinel lymph node mapping Prognosis for colorectal cancer is dependent on radical surgical intervention. Chemotherapy in patients with advanced disease has improved the survival. A considerable proportion of the patients going through radical...... surgery will subsequently relapse. Adjuvant chemotherapy is reserved for patients with lymph node metastases, why undetected malignant lymph nodes will result in understaging and exclusion from the possible benefit of adjuvant chemotherapy. With sentinel lymph node mapping it may be possible to detect...

  10. Behandling af blødende øsofagusvaricer med selvekspanderende metalstenter

    DEFF Research Database (Denmark)

    Dahlerup, Jens F; Kruse, Aksel; Grønbaek, Henning;

    2007-01-01

    We report that haemostasis was obtained by the use of SEMS in two patients with bleeding oesophageal varices which failed conventional therapy (vasoactive drugs, antibiotics, endoscopy, and Sengstaken balloon tamponade). One patient subsequently died of sepsis; the other was treated with TIPS...

  11. Radium-223 behandling af knoglemetastaser ved kastrationsrefraktær prostatacancer

    DEFF Research Database (Denmark)

    Mortensen, Jann; Højgaard, Liselotte

    2014-01-01

    The alpha emitter Radium-223 ((22)3Ra-Cl2) is a bone-seeking radionuclide studied as a new treatment for patients with bone metastases from hormone refractory prostate cancer. More than 1,000 patients have been included in clinical phase I-III tests showing significant reduction in alkaline...

  12. Behandling af uraemisk osteodystrofi med laegemidler, som påvirker calcium-fosfor-omsaetningen

    DEFF Research Database (Denmark)

    Vestergaard, Peter; Eiken, Pia A

    2012-01-01

    This review discusses the mineral bone disorders in patients with chronic kidney disease. We focus on the management of these conditions by administration of calcium, vitamin D (ergocalciferol and cholecalciferol), vitamin D receptor activators (calcitriol, alphacalcidiol), phosphate binders...

  13. Ny behandling af peritoneal karcinose fra kolorektal cancer. Cytoreduktiv kirurgi og hyperterm intraperitoneal kemoterapi

    DEFF Research Database (Denmark)

    Iversen, Lene Hjerrild; Rasmussen, Peter C; Laurberg, Søren

    2007-01-01

    Peritoneal carcinomatosis (PC) is commonly seen in colorectal cancer and is uniformly fatal. Cytoreductive surgery (CS) combined with hyperthermic intraperitoneal chemotherapy (HIIC) is a new treatment in strictly selected patients with PC. CS includes peritonectomy procedures and resection of in...

  14. Disease-modifying anti-rheumatic drugs til behandling af ankyloserende spondylitis

    DEFF Research Database (Denmark)

    Madsen, Ole Rintek; Egsmose, Charlotte

    2009-01-01

    Ankylosing spondylitis (AS) is an inflammatory disorder affecting the axial skeleton, peripheral joints, entheses and extra-articular sites. Patients with early disease, a higher level of erythrocyte sedimentation rate and/or peripheral arthritis might benefit from sulfasalazine. Otherwise...

  15. Endokrinologisk udredning, behandling og opfølgning af polycystisk ovariesyndrom

    DEFF Research Database (Denmark)

    Glintborg, Dorte; Rungby, Jørgen; Eskildsen, Peter;

    2010-01-01

    Polycystic ovary syndrome (PCOS) has a prevalence of 5-10% and is defined as oligomenorrhoea, hyperandrogenaemia and/or polycystic ovaries and the exclusion of other aetiologies for the patient's symptoms. There is currently no agreement on the initial evaluation programme for women referred...... with PCOS or on how the syndrome should be treated. Women with PCOS have an increased risk of the metabolic syndrome upon diagnosis and increased long-term risk of type 2 diabetes, cardiovascular disease and endometrial cancer. In the present overview, we give recommendations for relevant follow......-up examination of patients with PCOS based on a search of the available literature. Udgivelsesdato: 2010-Jan-18...

  16. Behandling af idiopatisk perifer facialisparese, også kaldet Bells parese

    DEFF Research Database (Denmark)

    Meyer, Martin Willy; Hahn, Christoffer Holst

    2013-01-01

    Bell's palsy is defined as an idiopathic peripheral facial nerve paralysis of sudden onset. It affects 11-40 persons per 100,000 per annum. Many patients recover without intervention; however, up to 30% have poor recovery of facial muscle control and experience facial disfigurement. The aim...

  17. Diagnostik og behandling af kvinder med urin-inkontinens på danske gynaekologiske afdelinger

    DEFF Research Database (Denmark)

    Vejtorp, M; Fischer-Rasmussen, W; Blaabjerg, J

    1990-01-01

    The routine practice in the diagnosis and treatment of urinary incontinence was investigated by means of a questionnaire to which all 32 departments replied. Miction charts were employed routinely in 17 departments and for selected patients in eight departments. Weighing of diapers was employed...

  18. Konservativ behandling af sårinfektioner efter operation for mammacancer

    DEFF Research Database (Denmark)

    Lanng, Charlotte; Hoffmann, Jack

    2002-01-01

    treated conservatively with repeated aspiration or replacement of the drain, 5% had spontaneous perforation of the wound abscess, corresponding to a small area of necrosis, and healed without operation. Five per cent had a major area of necrosis with underlying infections. These patients had their wound...

  19. Udformning af en forskningsprotokol

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Ottesen, Aase Marie

    2008-01-01

    Nogle demenssygdomme rammer især de forreste dele af hjernen, hvilket hos den enkelte person kan medføre svære psykiatriske symptomer. Der findes ingen specifik behandling af grundsygdommene for disse frontotemporaledemenstilstande, og symptomatisk medikamentel behandling af de psykiatriske sympt...

  20. Ventetid og omkostninger ved diagnostik og behandling af stabil angina pectoris

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Sanchez, Ricardo

    Introduction: The objective of this pilot study was to examine possible consequences of a logistically non-optimal regimen, for the diagnosis and treatment of stable angina pectoris, on waiting time and costs to inform whether a larger study is warranted. Material and methods: Retrospective cohort...... study among 104 consecutive patients referred on suspected stable angina pectoris. Data on the diagnostic regimen was systematically collected from patient files and data on other resource use was collected using a questionnaire for self- reporting. Non-parametric bootstrapping was applied. Results...... of stable angina pectoris, which ceteris paribus would be associated with cost savings in the health care sector. However, these potentials should be examined in a larger- scale study....

  1. Endokrinologisk udredning, behandling og opfølgning af polycystisk ovariesyndrom

    DEFF Research Database (Denmark)

    Glintborg, Dorte; Rungby, Jørgen; Eskildsen, Peter;

    2010-01-01

    with PCOS or on how the syndrome should be treated. Women with PCOS have an increased risk of the metabolic syndrome upon diagnosis and increased long-term risk of type 2 diabetes, cardiovascular disease and endometrial cancer. In the present overview, we give recommendations for relevant follow......Polycystic ovary syndrome (PCOS) has a prevalence of 5-10% and is defined as oligomenorrhoea, hyperandrogenaemia and/or polycystic ovaries and the exclusion of other aetiologies for the patient's symptoms. There is currently no agreement on the initial evaluation programme for women referred...

  2. Behandling af brandskader

    DEFF Research Database (Denmark)

    Lang, Christian Lyngsaa; Partoft, Søren; Astrup, Jakob;

    2015-01-01

    This paper aims to clarify the newly revised guidelines regarding burn injuries as to assist medical personnel dealing with burns. The Department of Burns at Rigshospitalet is the main burn centre in Denmark, and thus creates the National Guidelines of burns treatment. The new guidelines have...

  3. Korrekt behandling af forfrysninger

    DEFF Research Database (Denmark)

    El-Charnoubi, Waseem Ghulam; Bonde, Christian; Alsbjørn, Bjarne F

    2011-01-01

    Frostbite is rare in Denmark and is often associated with psychiatric conditions or drug- and alcohol abuse. It is seen regularly in countries with an arctic climate and tradition for outdoor activities such as skiing and climbing. The past winter in Denmark was long and cold, so we may see this ...... this phenomenon more frequently in the future. We report two cases from the winter 2009/2010 and summarize the pathophysiology and briefly present the treatment strategy....

  4. Behandling af infantile spasmer

    DEFF Research Database (Denmark)

    Hansen, Lars Kjaersgård; Rasmussen, Niels Henrik

    2006-01-01

    Infantile spasms (IS) are characterised by neurodevelopmental regression, a unique type of seizures and a hypsarrhythmic EEG pattern. Studies recommend the medical treatment of IS as a positive short-term outcome with respect to the spasms and in the resolution of the hypsarrhythmia. However, the...

  5. Korrekt behandling af forfrysninger

    DEFF Research Database (Denmark)

    El-Charnoubi, Waseem Ghulam; Bonde, Christian; Alsbjørn, Bjarne F

    2011-01-01

    Frostbite is rare in Denmark and is often associated with psychiatric conditions or drug- and alcohol abuse. It is seen regularly in countries with an arctic climate and tradition for outdoor activities such as skiing and climbing. The past winter in Denmark was long and cold, so we may see...

  6. Behandling af Dupuytrens kontraktur

    DEFF Research Database (Denmark)

    Raundrup Kornø, Maj; Søe, Niels Henrik; Dahlin, Lars B

    2015-01-01

    Dupuytren’s disease treatment Dupuytren’s disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Gen­erally, tr......Dupuytren’s disease treatment Dupuytren’s disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Gen...

  7. Segmentel vending af tyndtarmen til behandling af voksne patienter med korttarms syndrom

    DEFF Research Database (Denmark)

    Burgdorf, Stefan K; Qvist, Niels; Gögenur, Ismail

    2014-01-01

    Short bowel syndrome is the result of extensive surgical resection, inherited defects or loss of functional absorbing intestine. Parenteral nutrition is associated with high economical expenses, increased morbidity and decreased quality of life. Intestinal transplantation is associated with high...... morbidity and mortality rates. Segmental reversal of the small bowel can prolong the transit time in the small bowel and in many cases permanently end parenteral nutrition dependency. Segmental reversal of the small bowel should be integrated in the surgical treatment of adults with short bowel syndrome....

  8. Karkirurgisk behandling hos patienter med påvirket nyrefunktion

    DEFF Research Database (Denmark)

    Hensler, M K; Forrest, M; Lorentzen, Jørgen Ewald

    1994-01-01

    and blood pressure status was evaluated preoperatively and at follow-up. The perioperative mortality was 5% (n = 2) and morbidity 21% (n = 9). At discharge from hospital renal function was maintained in 38 patients (90%), including three patients who at the time of operation were without diuresis and had...

  9. Legionella pneumoni hos patienter, der er i behandling med infliximab

    DEFF Research Database (Denmark)

    Vinter, Hanne; Nielsen, Henrik Ib

    2009-01-01

    Therapy with tumour necrosis factor-alfa inhibitors is widely used in various inflammatory disorders, but adverse events from severe infections with intracellular pathogens may occur. We describe two cases of severe pulmonary legionellosis in patients treated with infliximab for Crohn's disease a...... and psoriasis, respectively. We conclude that legionella infections are probably more frequent in patients receiving immunosuppressive therapy with tumour necrosis factor-alfa inhibitors than in the background population. Udgivelsesdato: 2009-Jan-19...

  10. Teknologiers mellemkomst i ambulant behandling og egenomsorg

    DEFF Research Database (Denmark)

    Ballegaard, Stinne Aaløkke; Aarhus, Rikke

    2009-01-01

    Vigtige tendenser i den danske sundhedssektor i disse år er centralisering af behandling og øget egenomsorg. Teknologi ses ofte som en del af denne udvikling, omend der eksisterer både dystopiske og utopiske forestillinger om, hvorvidt teknologi fremmedgør eller støtter patienten. I denne artikel...

  11. En krobjektiv lidelse? Forståelse og behandling af kroniske, diffuse smertelidelser med fibromyalgi som eksempel

    Directory of Open Access Journals (Sweden)

    Rie Lykke Danielsen

    2011-12-01

    Full Text Available The article deals with the disease field chronic diffuse pains, here exemplified by fibromyalgia, where patients are frequently rendered homeless in an objectivity focused medical treatment system, whose specialities (ideally seen are mutually exclusive, and where the absence of a diagnosis therefore poses a fundamental problem. In the treatment field there is, however, also a bio-psycho-social approach, and these two treatment regimes are respectively termed as a chrObjective approach and a holistic subject approach.By empirical examples, from stories by both therapists and patients, the article describes how the actors navigate between the two treatment regimes, to which the patients must necessarily adapt in their wish for acceptance and assistance from both sides. The authors further discuss to which degree the two treatment regimes are actually incompatible. The interviews and observation of participants, which constitute the empirical basis for the article, were carried out among therapists and patients in Denmark in 2010.

  12. Behandling af renovaskulær hypertension med transluminal angioplastik--13 års erfaring--sekundærpublikation

    DEFF Research Database (Denmark)

    Øvrehus, Kristian Altern; Andersen, Poul Erik; Jacobsen, Ib Abildgaard

    2008-01-01

    The result of treatment of renovascular hypertension by renal angioplasty over a period of 13 years was analysed. Patients with a positive diagnostic work-up with renography or renal vein renin measurement had renal angiography performed and in cases of renal artery stenosis, transluminal...... angioplasty. A total of 124 patients were treated; 31% were normotensive immediately after angioplasty, 59% had improved blood pressure control and 10% had unchanged hypertension. The corresponding figures after six months and at the latest follow-up were 13, 72 and 15%. Udgivelsesdato: 2008-Jan-21...

  13. Angiotensin I konverteringshaemmeren enalapril til behandling af progredierende kronisk nefropati. En åben randomiseret kontrolleret undersøgelse

    DEFF Research Database (Denmark)

    Kamper, A L; Strandgaard, S; Leyssac, P P

    1993-01-01

    In order to study the influence of angiotensin converting enzyme (ACE) inhibition on the progression of chronic nephropathy, 70 patients with a median glomerular filtration rate (GFR) of 15 (range, 6 to 54) mL/min/1.73 m2 were randomised in an open study to basic treatment with enalapril...... or conventional antihypertensive treatment. The patients were followed for at least two years or until they needed dialysis. The therapeutic goal, was a blood pressure of 120 ti 140/80 to 90 mmHg. In the enalapril group, the median decline in GFR was -0.20 (range, +0.18 to -7.11) mL/min/1.73 m2/month...

  14. Behandling af defaekationsblokade som følge af dyb fossa recto-genitalis med total baekkenbundsrekonstruktion med Prolene-net

    DEFF Research Database (Denmark)

    Møller, P; Monrad, H; Kehlet, H

    1992-01-01

    of the abdominal pain and dependence on morphine in two of the patients. Rectal compression resulting from an abnormally deep recto-genital fossa should be included in the differential diagnostic deliberations in patients with severe constipation and defaecation blockage. Complete reconstruction of the pelvic......The causes of severe defaecation blockage resulting from compression of the rectum and deep recto-genital fossa are reviewed and are illustrated by three patients who had previously undergone hysterectomy and who had incapacitating defaecation blockage and abdominal pain requiring morphine in two...... of the patients. The condition had not been diagnosed despite previous hospital contact for many years in two of the patients. Complete reconstruction of the pelvic floor with prolene net was performed. Subsequent defaecography showed normalization of defaecation without rectal compression and with relief...

  15. Patienters vurdering af medicinpakningernes indlaegssedler

    DEFF Research Database (Denmark)

    Horwitz, Anna; Reuther, Lene; Andersen, Stig Ejdrup

    2009-01-01

    effects had made them stop taking their medicine. Future studies should bring into focus the reason for medication adherence, how written information can be made easier to read, comprehensive and correct without contributing to anxiety and non-adherence. Udgivelsesdato: 2009-Feb......INTRODUCTION: The objective was to investigate patients' perception of patient information leaflets, including their readability, comprehensibility and their impact on adherence. MATERIAL AND METHODS: A 14-item questionnaire was prepared and answered by unselected patients in a general practice...... in Copenhagen. RESULTS: A total of 111 patients were included. Eighty-eight patients (79%) always or often read the patient information leaflets. Among these, 77% attached importance to adverse effects. A mere 13% attached importance to all leaflet information. In all, 21% never or rarely read patient...

  16. Assisteret hjemmebehandling af eksacerbation i kronisk obstruktiv lungesygdom. Fremskyndet udskrivelse til fortsat behandling, monitorering og pleje i eget hjem varetaget af lungesygeplejerske

    DEFF Research Database (Denmark)

    Ringbaek, Thomas Jørgen; Eriksen, Nanna; Vestbo, Jørgen

    2003-01-01

    of COPD. In order to evaluate various types of assisted home care, the selection of patients, feasibility, effect, safety, and cost-effectiveness, the literature was reviewed. Most information is available on assisted home care following a hospital-based assessment and led by a respiratory nurse......Chronic obstructive pulmonary disease (COPD) is a leading cause of hospitalisation in Danish adults, and admission rates are expected to increase in the future. Assisted home care with disease monitoring and treatment by a pulmonary nurse may reduce time spent at hospital and the economic burden...

  17. Diagnostik og behandling af trigeminusneuralgi

    DEFF Research Database (Denmark)

    Maarbjerg, Stine; Heinskou, Tone Bruvik; Wolfram, Frauke

    2016-01-01

    Trigeminal neuralgia (TN) is characterized by unilateral evoked short-lasting intense pain paroxysms in the face. A concomitant persistent background pain is frequently present. Neurovascular contact causing displacement or atrophy of the trigeminal nerve is important to TN aetiology. TN can also...

  18. Behandling af astma hos gravide

    DEFF Research Database (Denmark)

    Akram, Iram; Ulrik, Charlotte Suppli; Johnsen, Claus Rikard

    2016-01-01

    Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least...... due to suboptimal adherence with controller therapy and pregnant women's concerns about harmful effects of medication on the fetus. This review provides an update on the safety of asthma medication during pregnancy, based on recent clinical studies and international guidelines....

  19. Biologisk behandling af spondylitis ankylopoietica

    DEFF Research Database (Denmark)

    Freiesleben, S.; Schou, M.

    2008-01-01

    All of the three well-known TNF alpha inhibitors (infliximab, adalimumab and etanercept) have a rapidly occurring and long-lasting effect in ankylosing spondylitis (AS). The IL-1 antagonist, anakinra, has been investigated in two open label studies with partially conflicting results. Apart from...

  20. Behandling af neuroendokrine gastrointestinale tumorer

    DEFF Research Database (Denmark)

    Hansen, Carsten Palnaes; Langer, Seppo; Frevert, Susanne;

    2010-01-01

    of cure. Palliative therapy includes surgery and intra-arterial embolization of hepatic metastases, chemotherapy, biotherapy with interferon-alpha and radionuclear treatment. Tumour-targeted therapy with tyrosine kinase inhibitors, mammalian target of rapamycin inhibitors or monoclonal antibodies...

  1. Diagnostik og behandling af fenylketonuri

    DEFF Research Database (Denmark)

    Bayat, Allan; Møller, Lisbeth Birk; Lund, Allan Meldgaard

    2015-01-01

    Primary phenylalanine hydroxylase deficiency, also known as phenylketonuria, results in accumulation of phenylalanine in the blood. Early identification and treatment prevents the majority of clinical sequelae to the disease, but psychological and neurodevelopmental problems can occur in some...

  2. Kirurgisk behandling af cancer pancreatis

    DEFF Research Database (Denmark)

    Bergenfeldt, Magnus; Hansen, Carsten Palnaes; Mortensen, Michael Bau

    2010-01-01

    Surgery remains the only hope for cure in pancreatic cancer. The most common procedures are reviewed. Postoperative morbidity and mortality below 30% and 5%, respectively, are the standard. The benefit of extended lymph node dissection and portal-mesenteric vein resection is dubious. Selected...

  3. Behandlingseffekt af Digital Dermatitis

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    af klovlidelser herunder især Digital Dermatitis. Klovregistreringerne viser, at der er stor dynamik og mange nyinfektioner af Digital Dermatitis svarende til problematikken ved mastitis. Behandlingseffekten ved Digital Dermatitis er høj (omkring 90 %) ved den udførte behandling. Behandlingen bestod...

  4. Implementering af evidensbaseret praksis

    DEFF Research Database (Denmark)

    Scheel, Linda Schumann; Tewes, Marianne; Petersen, Preben Ulrich

    2015-01-01

    Projektet omhandler implementering af den kliniske retningslinje om identifikation, forebyggelse og behandling af delirium – i denne sammenhæng relateret til hjertepatienter. Projektet foregår på to hospitaler i Hjertecentret på Rigshospitalet, et intensivt afsnit og et sengeafsnit, i tæt...

  5. Implementering af evidensbaseret praksis

    DEFF Research Database (Denmark)

    Scheel, Linda Schumann; Hansen, Ida Rode

    2014-01-01

    Projektet omhandler implementering af den kliniske retningslinje om identifikation, forebyggelse og behandling af delirium – i denne sammenhæng relateret til hjertepatienter. Projektet foregår på to hospitaler i Hjertecentret på Rigshospitalet, et intensivt afsnit og et sengeafsnit, i tæt...

  6. Poser af papir og plast

    DEFF Research Database (Denmark)

    Thygesen, Jette

    2007-01-01

    Artiklen behandler de problemstillinger der er i forbindelse med fortolkning af det afgiftspligtige vareområde. I henhold til lov om afgift af visse emballager, poser, engangsservice, og pvc-folier, svares der afgift af poser, såfremt de frembyder bestemte karakteristika, herunder særligt om de er...

  7. Behandling med dopaminagonister og udvikling af hjerteklapsygdom hos patienter med hyperprolaktinæmi

    DEFF Research Database (Denmark)

    Steffensen, Maria Charlotte; Mægbæk, Merete Lund; Laurberg, Peter

    2014-01-01

    Treatment with dopamin agonists, particularly cabergoline, is the primary and preferred therapy for prolactinomas and symptomatic hyperprolactinaemia due to its effectiveness and tolerability. However, an association has been demonstrated between fibrotic heart valve disease and high-dose dopamin...

  8. Toksoplasmose-chorioretinitis: klinisk forløb og behandling af syv patienter

    DEFF Research Database (Denmark)

    Lebech, A M; Lebech, M; Børme, K K

    1996-01-01

    Toxoplasmosis is a major and preventable cause of severe visual loss and blindness in young people. Ocular toxoplasmosis is the leading cause of posterior uveitis and in most cases it represents a late manifestation of a congenital infection. The clinical picture and anti-Toxoplasma therapy...

  9. ARCgame - gamification af undervisning

    DEFF Research Database (Denmark)

    Jensen, Camilla Gyldendahl

    2014-01-01

    Gamification er et begreb, der anvendes til at beskrive brugen af spilelementer i andre miljøer for at forbedre brugernes oplevelse. Følgende tekst har til formål at behandle emnet i forhold til af opnå en forståelse for de elementer der indvirker på en ”gamification af et undervisningsforløb”, her...

  10. Tilfredshedsundersøgelse af Palliativt Team Fyn

    DEFF Research Database (Denmark)

    Paulsen, Maja Skov

    2007-01-01

    Behandling af døende patienter i eget hjem kan være en vanskelig og udfor­ drende opgave. Målet med behand­ lingen skifter fra kurativt til lindrende, hvilket udfordrer selvopfattelsen som be­ handler, og samtidig vil palliativ behand­ ling ofte rumme komplicerede medicinsk faglige problemstillin...... problemstillinger samt eksisten­ tielle spørgsmål. Gennem de senere år er der etableret specialiserede palliative teams med udgående funktioner som støtte til de primære behandlere af dø­ ende mennesker....

  11. Identifying Patients at Risk and Patients in Need

    DEFF Research Database (Denmark)

    Schmidt, Thomas

    2015-01-01

    En væsentlig andel af patienter oplever forværring under indlæggelse på Fælles Akutmodtagelsen (FAM). At identificere disse forværringer før de bliver alvorlige er vanskeligt for klinikere eftersom de behandler meget forskellige patienter under et stort pres for at bevare overblik og årvågenhed. ...

  12. Efterisolering af etageboliger

    DEFF Research Database (Denmark)

    Munch-Andersen, Jørgen

    Denne anvisning behandler efterisolering af etageboliger bygget i perioden 1850-1977. Der gøres rede for de grundlæggende principper for efterisolering og de bygningsfysiske krav til de enkelte bygningsdele. Anvisningen indeholder desuden vejledning i, hvordan efterisolering udføres i henholdsvis...

  13. OPUS: Randomiseret multicenterundersøgelse af integreret behandling sammenlignet med standardbehandling før første psykoseepisode--sekundaerpublikation

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Petersen, Lone; Jeppesen, Pia;

    2006-01-01

    A total of 547 patients with first-episode psychosis were included in a randomised clinical trial comparing integrated treatment with standard treatment. The integrated treatment consisted of assertive community treatment with programmes for family involvement and social skills training. Patients...

  14. Fysisk traening som behandling af nedsat funktionsevne hos svage, hjemmeboende 75+ -årige. Et randomiseret interventionsstudie i almen praksis omfattende elementer til en teknologivurdering

    DEFF Research Database (Denmark)

    Vad, Esther; Worm, Charlotte; Lauritsen, Jens;

    2002-01-01

    The aim of this study was to establish the value of physical training as a treatment of reduced physical ability in frail, elderly patients living at home.......The aim of this study was to establish the value of physical training as a treatment of reduced physical ability in frail, elderly patients living at home....

  15. Træning har positiv effekt på helbredsrelateret livskvalitet hos kræftpatienter i behandling--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Lønkvist, Camilla Kjær; Højman, Pernille; Gehl, Julie;

    2013-01-01

    and reduces risk of recurrence and mortality from breast- and colon cancer. Considerable efforts go to patient care and rehabilitation, both during and after cancer treatment. This new systematic review implies that exercise programmes should be a central part of rehabilitation for all cancer patients.......Cancer and treatment of cancer affects the health-related quality of life (HRQoL) in patients. A recent Cochrane review concludes that exercise may have positive effects on HRQoL and several other domains. Other reviews have shown that physical activity may protect against development of cancer...

  16. Implementering af ny instruks for forebyggelse af Post Operativ Urin Retention (POUR) i forhold til den hoftealloplastik opererede patient

    DEFF Research Database (Denmark)

    Bagger, Bettan; Bech Hansen, Anette; Hørdam, Britta

    2013-01-01

    Pro-hip www.prohip.eu har til formål at evidensbasere den rehabiliterende sygepleje til hoftepatienten i forhold til indsatsområderne; ernæring, urinretention/UVI, delir og tryksår. På baggrund af flere erfaringer med forekomst af POUR hos den hoftealloplastik opererede patient på Næstved Hospital...

  17. Kirurgisk behandling af cancer ventriculi på et universitetshospital. En retrospektiv opgørelse for perioden 1990-1995

    DEFF Research Database (Denmark)

    Hillingsø, Jens; Hviid, Kirsten; Mynster, T;

    2001-01-01

    AIM: A retrospective study of 69 cases of gastric cancer seen during the period from 1/1-1990 to 31/12-1994 treated in a University Hospital. The aim of the study was to describe morbidity, mortality and identify independent prognostic variables for mortality. METHOD: Patient data were recovered.......001) as independent variables. DISCUSSION: The overall five-year survival is low and has not changed over two decades in Denmark, whereas mortality and morbidity rates have improved. It should be recommended that: The treatment of gastric cancer must be centralised in order to develop preoperative examinations...... from the hospital's central database. Mortality was chosen as end-parameter. Univariate log-rank-test identified statistically significant variables which were then analysed by Cox backward stepwise regressional analysis. MATERIAL: Sixty-nine patients were available for analysis, median age 73 years...

  18. Risikostratificering af patienter med diabetes mellitus

    DEFF Research Database (Denmark)

    Qvist, Peter; Glintborg, Dorte; Andries, Alin

    2008-01-01

    with diabetes mellitus. MATERIAL AND METHODS: We included patients with diabetes from the catchment areas of four diabetes out-patient clinics in southern Denmark. Patients were risk-stratified to 3 follow-up levels (level 1 - follow-up only by their GP, level 2 - intensified follow-up by GP and/or shared care...... schemes, level 3 - follow-up only in out-patient clinics). The results were subsequently compared with the patients' actual follow-up status. RESULTS: A total of 647 patients (563 type 2 diabetes and 84 type 1 diabetes) were included from 15 GPs. Among these, 139 were stratified to level 1, 409 to level 2...

  19. Patient med nedsat leverfunktion fik myoklonier under behandling med selektive serotoningenoptagelseshæmmere

    DEFF Research Database (Denmark)

    Forsberg-Gillving, Mimmi; Bode, Matthias; Sindrup, Søren Hein

    2015-01-01

    Side effects such as myoclonus and tremor are rare when treating with selective serotonin reuptake inhibitors (SSRIs). We present a case where a patient with known liver cirrho-sis and in treatment with citalopram developed myoclonus, tremor and gait difficulties. The symptoms were reduced when...

  20. Rehabilitering af patienter med Cerebral Parese

    DEFF Research Database (Denmark)

    Smærup, Michael; Grode, Jesper Nicolai Riis; Væggemose, Poul Erik;

    2015-01-01

    . Studier har dog vist at exergames (øvelser + spil) kan virke motiverende på patienter og har vist sig at kunne forbedre outcome efter en given træningsperiode. I nærværende projekt var målet derfor at afdække, udvikle og afprøve en mulig sundhedsteknologisk løsning for at træne meningsfulde dagligdags...

  1. Ny behandling af kronisk hepatitis B

    DEFF Research Database (Denmark)

    Andersen, Ellen Sloth; Weis, Nina M

    2008-01-01

    Worldwide, 350 million people are infected with chronic hepatitis B. Over the last few years, it has been possible to treat chronic hepatitis B. Treatment very often consists of nucleos(t)ide analogs and in a few cases of pegylated alpha-interferon. In 2007, a new nucleoside analog, Telbivudine......, was approved to treat chronic hepatitis B. In phase II and ongoing phase III studies, Telbivudine has proven more effective than the nucleoside analog, Lamivudine, which was very often used up until recently. Udgivelsesdato: 2008-Nov-24...

  2. Kirurgisk behandling af aldersrelateret makuladegeneration (AMD)?

    DEFF Research Database (Denmark)

    Kiilgaard, Jens Folke

    2001-01-01

    oftalmologi, aldersrelateret makuladegeneration, transplantation, grise, øjne, kirurgisk udvikling......oftalmologi, aldersrelateret makuladegeneration, transplantation, grise, øjne, kirurgisk udvikling...

  3. Fysisk aktivitet - en behandling af erektil dysfunktion

    DEFF Research Database (Denmark)

    Gerbild, Helle Nygaard

    2016-01-01

    Erectile dysfunction (ED) is typically linked to the risk factors: Physical inactivity, obesity, hypertension, metabolic syndrome, diabetes mellitus or cardiovascular diseases. This thesis results in novel knowledge showing that physiotherapists with guidance on physical activity may contribute...

  4. Impotens forarsaget af behandling med methotrexat

    DEFF Research Database (Denmark)

    Penninga, Ida Elisabeth Irene; Larsen, H.K.; Andersen, S.E.

    2008-01-01

    Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective...... impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously Udgivelsesdato: 2008/1/28...

  5. Diagnostik og behandling af øsofagusperforationer

    DEFF Research Database (Denmark)

    Novrup, Hans Gram; Mortensen, Michael Bau; Jungersen, Dorte

    2011-01-01

    The treatment of oesophageal perforations (EP) has primarily been a surgical issue and despite significant advances in surgery and intensive care medicine EP is continuously associated with high morbidity and mortality. Implementation of an effective treatment algorithm which steps away from...... and the establishment of a controlled fistula....

  6. Smitteopsporing og profylaktisk behandling af tuberkulose

    DEFF Research Database (Denmark)

    Seersholm, Niels; Wilcke, Torgny

    2011-01-01

    Contact tracing is an integrated part on tuberculosis management and is conducted by the medical officer in collaboration with the local chest clinics. The principle of contact tracing is to begin with the household contacts and expanding to more peripheral contacts depending of the number...

  7. Diagnostik og behandling af akut colonpseudoobstruktion

    DEFF Research Database (Denmark)

    Ertberg, Pia; Vilandt, Jesper; Bødker, Birgit

    2013-01-01

    Acute colonic pseudo-obstruction (ACPO), also known as Ogilvie's syndrome, is a clinical condition with acute dilatation of the colon without a provable mechanical cause. Early recognition and treatment of the condition is important in order to improve the outcome. The diagnosis is based on clini...

  8. Kirurgisk behandling af type 2-diabetes

    DEFF Research Database (Denmark)

    Olesen, Stine Chabert; Hansen, Dorte Lindqvist; Almdal, Thomas;

    2009-01-01

    on appetite-regulating gut hormone, particularly peptide YY and glucagon-like peptide-1. Nevertheless, other unknown hormones or mechanisms may be involved in the dramatic changes in the glucose metabolism. Development of new drugs and treatments based on the endocrine changes observed after bariatric surgery...

  9. Diagnostik og behandling af neuromyelitis optica

    DEFF Research Database (Denmark)

    Nielsen, Helle Hvilsted; Ravnborg, Mads; Illes, Zsolt

    2014-01-01

    Neuromyelitis optica (NMO) is an inflammatory demyelinating disease characterized by antibodies against aquaporin-4 in up to 80% of the cases and even less in the NMO spectrum disorders, which may be difficult to distinguish from early multiple sclerosis. While immunosuppressive therapy should...

  10. Moderne behandling af type B-aortadissektion

    DEFF Research Database (Denmark)

    Klitfod, L.; Baekgaard, N.; Just, S.

    2008-01-01

    Rapid classification is essential in the management of aortic dissections, as Type A dissections require surgery, while the optimal treatment of Type B dissections is controversial. Medical treatment with antihypertensive medication and analgesics has so far been the main treatment of uncomplicated...... Type B dissections, while surgery has been reserved for complications and persistent pain in spite of medical treatment. Endovascular techniques are less invasive than open repair and show promising early results Udgivelsesdato: 2008/9/8...

  11. Udredning og behandling af osteoporotiske hoftefrakturer

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Abrahamsen, Bo

    2010-01-01

    Osteoporosis is a major cause of low-energy hip fractures. Although there are pharmacologic agents available for both prevention and treatment, less than 10% of hip fracture cases initiate anti-osteoporotic treatment.......Osteoporosis is a major cause of low-energy hip fractures. Although there are pharmacologic agents available for both prevention and treatment, less than 10% of hip fracture cases initiate anti-osteoporotic treatment....

  12. MINDFULNESS BEHANDLING AF DANSKE VETERANER - ET PILOTSTUDIE

    DEFF Research Database (Denmark)

    Fjorback, Lone

    2015-01-01

    I foråret 2014 mødtes en gruppe på 12 danske veteraner en gang om ugen i 9 uger for at deltage i programmet Mindfulness Baseret Stress Reduktion (MBSR). Deltagerne havde meldt sig frivilligt, og gruppen var blandet mht. alder, køn, antal udsendelser og diagnoser. Det, de havde til fælles, var...

  13. Udredning og behandling af autoimmun encefalitis

    DEFF Research Database (Denmark)

    Blaabjerg, Morten; Mærsk-Møller, Camilla C; Kondziella, Daniel;

    2015-01-01

    Autoimmune encephalitis with antibodies against neuronal surface antigens is diagnosed with increasing frequency in recent years. If treated early and aggressively, these conditions often respond favourably to immunotherapy. We describe the clinical features, diagnosis and treatment of the two mo...

  14. Ipilimumab til behandling af metastaserende melanoma

    DEFF Research Database (Denmark)

    Ghasemi, Habib; Schmidt, Henrik; Stolle, Lars Bjørn

    2015-01-01

    Until recently metastatic melanoma was a disease with limited treatment options and a poor prognosis. However, new promising products have been developed. Ipilimumab, a full human anti-cytotoxic T-lymphocyte antigen-4 antibody, has shown improved survival in several clinical trials and is now...... a part of the standard treatment options for this disease in Denmark. In this case report we present a 78-year-old man with metastatic melanoma who had complete remission after treatment with ipilimumab....

  15. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, A.C.; Sørensen, Helle Christina; Sander, Pia;

    2010-01-01

    INTRODUCTION: During the last decade, minimal invasive procedures have been introduced for treatment of urinary incontinence (UI) in women leading to shorter hospitalisation and fewer complications. The aim of this study was to outline clinical practice and attitudes among Danish UI surgeons. MAT...

  16. Momsmæssig behandling af vouchere

    DEFF Research Database (Denmark)

    Christiansen, Randi; Elgaard, Karina Kim Egholm

    2012-01-01

    and a-hydroxysalmeterol during visits one and two were 12.6 and 21.8%, respectively. The intra-individual variability of salmeterol and a-hydroxysalmeterol in the urine concentrations were significantly higher when uncorrected for USG with 43.0 and 43.7% versus 20.4% (p

  17. Psykoterapeutisk behandling af emotionelt ustabile personlighedsforstyrrelser

    DEFF Research Database (Denmark)

    Sørensen, Per; Kjølbye, Morten

    2015-01-01

    "Måske er vi samme person. Måske har vi ingen grænser. Måske strømmer vi gennem hinanden ubegrænset og storartet" (Ingmar Bergman, Fanny og Alexander, 1980)......."Måske er vi samme person. Måske har vi ingen grænser. Måske strømmer vi gennem hinanden ubegrænset og storartet" (Ingmar Bergman, Fanny og Alexander, 1980)....

  18. Abatacept til behandling af reumatoid artritis

    DEFF Research Database (Denmark)

    Nielsen, Henrik; Hansen, Annette

    2009-01-01

    Abatacept (CTLA4Ig) is a human fusion protein which consists of a cytotoxic lymphocytic-associated type 4 antigen which is bound to the Fc part of the IgG1. Abatacept binds to CD80/CD86 on antigen-presenting cells thus blocking the co-stimulatory signal to the naïve T cells and interfering with a...

  19. Kan forskellige velfærdsregimer betjenes af harmoniserede uddannelser?

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    2009-01-01

    Artiklen behandler dels Bologna-processen, dels etableringen af et marked for serviceydelser. Begge dele berører hidtidige sammenhæng mellem national uddannelse til et nationalt arbejdsmarked. Dog understreges, at den fortsatte nationale akkreditering af uddannelser modificerer virkningerne af...

  20. Evidens for akupunktur til patienter med kvalme og opkastning i forbindelse med kemoterapi? Et litteraturstudie

    DEFF Research Database (Denmark)

    Pedersen, Birgith; Bundgaard Sørensen, Lene; Stricker, Lisbeth;

    2008-01-01

    Patienter, der får kemoterapi med højemetogene stoffer lider stadig af kvalme og opkastning trods understøttende behandling med moderne antieemtika som 5HT3-antagonister eksempelvis ondansetron. Akupunkturstimulation anvendes for flere lidelser i sundhedsvæsenet og det undersøges om der er evidens...

  1. Does {sup 131}I-treatment of goitre result in an acute increase in the volume a function of the thyroid gland?; Medfoerer {sup 131}I-behandling af strufma en akut foroegelse af glandula thyreoideas volumen og funktion?

    Energy Technology Data Exchange (ETDEWEB)

    Nygaard, B.; Faber, J.O.; Hegedues, L.

    1995-12-01

    Many textbooks claim that radioiodine ({sup 131}I) treatment should be avoided in treatment of a goitre with substernal extension, due to fear of acute swelling of the gland with resulting respiratory problems. We examined patients with multinodular goitre, either nontoxic (n=20) or toxic (n=10) after treatment with {sup 131}I. An ultrasonically determined thyroid volume and thyroid function variables were investigated before and two, seven, 14, 21, 28 and 35 days after treatment. In nontoxic goitres the thyroid volume did not increase significantly, the maximum increase in the median volume being 4% on day 7. Serum levels of free T{sub 3} and free T{sub 4} indices increased by 20% (day 7) and 13% (day 14) (p=0.002), respectively. Likewise thyroid volume in toxic nodular goitre did not change significantly after {sup 131}I treatment. None of the patients presented symptoms of tracheal compression. We conclude that {sup 131}I treatment of nontoxic as well as toxic multinodular goitre does not seem to increase thyroid volume. (au) 18 refs.

  2. Skandinaviske kliniske retningslinjer for præhospital behandling af patienter med svære hovedtraumer

    DEFF Research Database (Denmark)

    Juul, Niels; Sollid, Snorre; Sundstrøm, Terje;

    2008-01-01

    Head trauma causes the death of many young persons. The number of fatalities can be reduced through systematic management. Preventing secondary brain injury together with the fastest possible transport to a neurosurgical unit has been shown to be effective in reducing mortality and morbidity...

  3. Blødningsforstyrrelser hos kvinder. Undersøgelse og behandling i almen praksis

    DEFF Research Database (Denmark)

    Astrup, Karen

    1994-01-01

    Artiklen omfatter resultaterne af en spørgeskemaundersøgelse til 200 praktiserende læger efteråret 1992 om lægernes undersøgelse og behandling af forskellige former for blødningsforstyrrelser hos kvinder i almen praksis. Undersøgelsen blev udført mhp. Karen Astrup's deltagelse i expertpanelet til...... konsensuskonferencen "Blødningsforstyrrelser hos kvinder" febr. 1993. Udgivelsesdato: 1994......Artiklen omfatter resultaterne af en spørgeskemaundersøgelse til 200 praktiserende læger efteråret 1992 om lægernes undersøgelse og behandling af forskellige former for blødningsforstyrrelser hos kvinder i almen praksis. Undersøgelsen blev udført mhp. Karen Astrup's deltagelse i expertpanelet til...

  4. Valg af behandling af akut, purulent divertikulitis er uafklaret

    DEFF Research Database (Denmark)

    Hupfeld, Line; Burcharth, Jakob; Pommergaard, Hans-Christian;

    2015-01-01

    Inflammation in colonic diverticula can develop into acute diverticulitis. Treatment varies depending on illness severity. Perforated diverticulitis with faecal peritonitis is treated surgically and Hartmann's procedure is the preferred operation. Peritoneal lavage might be an alternative...

  5. Evaluering af ordning med psykologbehandling af personer med let til moderat depression

    DEFF Research Database (Denmark)

    Fjeldsted, Rita; Christensen, Kaj Sparle

    tidligere evaluering af forsøgsordning af psykologbehandling af depression i perioden 2005-06. 18.419 personer i alderen 18-37 år blev henvist til psykolog i den undersøgte ordning i perioden 1.2.2009 – 31.1.2010, svarende til en henvisningshyppighed på 1,6 % af baggrundsbefolkningen i samme aldersgruppe...... samme niveau som fandtes i evalueringen fra 2007. Remissionsraten for personer med depression ved behandlingsstart er 87 % målt med MDI. Patienters selvrapporterede effekt er 95 %. I opfølgningsgruppen har 89 % ingen depression 3 år efter afsluttet behandling, 56 % har oplevet mindst én ny...... for begge køn, og der ses et fald på 40 % for kvinder og 70 % for mænd over de givne 3 år. Tidsperspektivet er for denne gruppe mere relevant for overordnet vurdering, men der savnes en sammenligningsgruppe. Ifølge spørgeskemadata øges andelen af personer, der er i arbejde, selvforsørgelse eller på SU fra...

  6. Effekten af geriatrisk intervention på rehabilitering af ældre patienter med hoftefraktur

    DEFF Research Database (Denmark)

    Gregersen, Merete; Mørch, Marianne Metz; Jensen, Niels Christian;

    2009-01-01

    Introduktion: Antallet af hoftefrakturer er stigende hos de 85+- årige, og det medfører et stort sengedagsforbrug. Årsagen er multifaktorielt betinget og skyldes oftest faldulykker og osteoporose. Materiale og metoder: Geriatrisk Teamfunktion på Ortopædkirurgisk Afdeling, geriatrisk rehabiliterin...

  7. Udvikling af virksomhedens transformationssystem (produktions- og distributionssystemet)

    DEFF Research Database (Denmark)

    Pagh, Janus Dore

    Denne ph.d.-afhandling behandler emnet udvikling af den industrielle produktionsvirksomheds transformationssystem, der omfatter virksomhedens samlede produktions- og distributionssystem. Der er i de senere år komet stigende fokus på virksomhedernes evne til at skabe differentieret og kundetilpass...

  8. Vurdering af omfang og konsekvenser af sprøjtning og gødskning af § 3-beskyttede naturarealer

    DEFF Research Database (Denmark)

    Strandberg, Morten Tune; Bak, Jesper Leth; Bladt, Jesper Stentoft;

    2012-01-01

    Det er overvejende de ferske enge, der gødskes og sprøjtes, hvorimod dette kun undtagelsesvist er konstateret på andre naturtyper som overdrev og heder m.m. De ferske enge er samtidig den mest udbredte § 3-naturtype. Behandling i form af gødskning og sprøjtning foregår anslået på op til 20 % af a...

  9. Forskning i ergoterapeutisk behandling indenfor neurorehabilitering - en stor udfordring og nødvendighed!

    DEFF Research Database (Denmark)

    Schow, Trine

    2011-01-01

    Der sker i disse år meget indenfor både forskning og behandling i neurorehabilitering. Både grundforskning og kliniske studier bidrager til viden om neuroplasticitet og til udvikling og dokumentation af forskellige behandlingsformer og det er vigtigt at det ergoterapeutiske felt følger med. Denne...

  10. Hospitalizations in patients with atrial fibrillation: an analysis from ROCKET AF

    Science.gov (United States)

    DeVore, Adam D.; Hellkamp, Anne S.; Becker, Richard C.; Berkowitz, Scott D.; Breithardt, Guenter; Hacke, Werner; Halperin, Jonathan L.; Hankey, Graeme J.; Mahaffey, Kenneth W.; Nessel, Christopher C.; Singer, Daniel E.; Fox, Keith A. A.; Patel, Manesh R.; Piccini, Jonathan P.

    2016-01-01

    Aims The high costs associated with treatment for atrial fibrillation (AF) are primarily due to hospital care, but there are limited data to understand the reasons for and predictors of hospitalization in patients with AF. Methods and results The ROCKET AF trial compared rivaroxaban with warfarin for stroke prophylaxis in AF. We described the frequency of and reasons for hospitalization during study follow-up and utilized Cox proportional hazards models to assess for baseline characteristics associated with all-cause hospitalization. Of 14 171 patients, 14% were hospitalized at least once. Of 2614 total hospitalizations, 41% were cardiovascular including 4% for AF; of the remaining, 12% were for bleeding. Compared with patients not hospitalized, hospitalized patients were older (74 vs. 72 years), and more frequently had diabetes (46 vs. 39%), prior MI (23 vs. 16%), and paroxysmal AF (19 vs. 17%), but less frequently had prior transient ischaemic attack/stroke (49 vs. 56%). After multivariable adjustment, lung disease [hazard ratio (HR) 1.46, 95% confidence interval (CI) 1.29–1.66], diabetes [1.22, (1.11–1.34)], prior MI [1.27, (1.13–1.42)], and renal dysfunction [HR 1.07 per 5 unit GFR < 65 mL/min, (1.04–1.10)] were associated with increased hospitalization risk. Treatment assignment was not associated with differential rates of hospitalization. Conclusion Nearly 1 in 7 of the moderate-to-high-risk patients with AF enrolled in this trial was hospitalized within 2 years, and both AF and bleeding were rare causes of hospitalization. Further research is needed to determine whether care pathways directed at comorbid conditions among AF patients could reduce the need for and costs associated with hospitalization. PMID:27174904

  11. Forebyggelse af dyb venetrombose (DVT) i underekstremiteter hos voksne hospitalsindlagte patienter gennem mobilisering

    DEFF Research Database (Denmark)

    Jensen, Jonna Gintberg

    2011-01-01

    Titel: Forebyggelse af dyb ventrombose (DVT) i underekstremiteterne hos voksne hospitalsindlagte patienter gennem mobilisering. Konklusion eller hovedbudskabet: Der foreligger ikke evidens for hvor meget, hvor længe og hvordan indlagte patienter skal mobiliseres for at forebygge dyb venetrombose(DVT......) Sideløbende med kursus i udvikling af kliniske retningslinjer har kursus deltagere og baggrundsgruppe - haft det mål, at undersøge hvilken evidens der foreligger i forhold til mobilisering af indlagte voksne patienter. Vores udgangspunkt tog afsæt i daglig klinisk praksis og en viden om, at DVT rammer en stor...... del af de indlagte patienter. Venøs trombose (VT) er den tredje største kardiovaskulære sygdom efter akut myokardieinfarkt og apopleksi (1). I et større norsk studie fandt man en incidensrate af VT på 1.43 per 1.000 personår, hvoraf dyb venetrombose (DVT) udgjorde 0.93 per 1.000 personår af de...

  12. U2AF1 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

    Directory of Open Access Journals (Sweden)

    Jun Qian

    Full Text Available Somatic mutations of U2AF1 gene have recently been identified in myelodysplastic syndrome (MDS and acute myeloid leukemia (AML. In this study, we analyzed the frequency and clinical impact of U2AF1 mutations in a cohort of 452 Chinese patients with myeloid neoplasms. Mutations in U2AF1 were found in 2.5% (7/275 of AML and 6.3% (6/96 of MDS patients, but in none of 81 CML. All mutations were heterozygous missense mutations affecting codon S34 or Q157. There was no significant association of U2AF1 mutation with blood parameters, FAB subtypes, karyotypes and other gene mutations in AML. The overall survival (OS of AML patients with U2AF1 mutation (median 3 months was shorter than those without mutation (median 7 months (P = 0.035. No difference in the OS was observed between MDS patients with and without U2AF1 mutations. Our data show that U2AF1 mutation is a recurrent event at a low frequency in AML and MDS.

  13. Fatal blødning ved operation for hoftenær fraktur hos en patient i behandling med dabigatran

    DEFF Research Database (Denmark)

    Rasmussen, Lasse Enkebølle; Viberg, Bjarke L; Pottegård, Anton

    2015-01-01

    An 82-year-old woman in treatment with the thrombin inhibitor dabigatran etexilate (a new oral anticoagulant (NOAC)) was admitted with a subtrochanteric femoral fracture and surgery was initiated 15 hours after admittance. She had a blood loss of 6,000 ml and died the next morning from multi......-organ failure. In 2013 1.8% of hip fracture patients in Funen received NOACs. Surgery is recommended within 24 hours for hip fracture patients to reduce mortality, but patients in treatment with NOACs should wait at least 48 hours before major surgery. Care should be taken when prescribing NOACs to patients...

  14. Brug af nervestimulator ved anlaeggelse af nervus ischiadicus-blokade hos en crusamputeret patient

    DEFF Research Database (Denmark)

    Heiring, Christian; Kristensen, Billy B

    2008-01-01

    We present a case of a sciatic nerve block performed with the nerve stimulation technique. This technique is normally not used in amputees because detection of a motor response to an electrical stimulation is impossible. In our patient the stimulation provoked a phantom sensation of movement...

  15. Håndtering af illikviditet i APV modellen

    DEFF Research Database (Denmark)

    Brandt, Mads; Dalgaard, Rune; Plenborg, Thomas

    2014-01-01

    Denne artikel behandler illikviditetspræmien i forbindelse med værdiansættelser. Mere præcist udledes den korrektion af illikviditetspræmien, der skal foretages, for at sikre konsistens i værdiansættelsen med henholdsvis Discounted Cash Flow (DCF) og Adjusted Present Value (APV) modellen. Artiklen...

  16. Review af Business Process Reengineering litteraturen fra 1990-98

    DEFF Research Database (Denmark)

    Wit, Camilla Kølsen de

    1998-01-01

    Formålet med papiret er dels at biddrage med et overblik over centrale kilder om BPR, og dels at kommentere udviklingen i litteraturens behandling af hhv. BPR begrebet og BPR projektet. Reviewet er bygget op om en kronologisk tabel, der opsummerer kildernes hovedsynspunkter....

  17. Tuberkulose forårsaget af Mycobacterium africanum

    DEFF Research Database (Denmark)

    Bek, Dorte; Kjeldsen, Marianne Kirstine; Hansen, Nikolaj Friis;

    2010-01-01

    Tuberkulose (TB) forårsages af patogene arter fra Mycobacterium tuberculosis komplekset (MTBC) og har en incidens på cirka 7/100.000 i Danmark. På mistanke om TB hos en akut indlagt 40 årig afrikansk mand initieredes anti-TB behandling. Efter 13 timers indlæggelse afgik patienten ved døden. Fra l...

  18. Relationship of plasma level of NT- ProBNP with development of AF in CABG patients

    Directory of Open Access Journals (Sweden)

    Tanaray B

    2010-10-01

    Full Text Available "nBackground: Studies of the association between post operative AF and Plasma level of NT- Pro BNP have reported conflicting findings. The aim of the present study was evaluation of the association between post coronary bypass graft- Atrial Fibrillation (AF and Plasma level of NT- ProBNP as an independent risk factor of AF development in patients undergoing coronary artery bypass graft."n "nMethods: In a cohort study, 79 patients with sinus rhythm who admitted in Imam Khomeini Hospital in Tehran, Iran, during February 2009 and February 2010 for CABG are included the study and followed for developing post operative AF rhythm."n "nResults: Post operative AF was found in 17.7% of patients. The peak time from the operation to the first AF episode was in second post op day in ten patients (71.4%. The serum level of ProBNP in patients with AF was significantly higher (1624± 647 versus 221± 238 pg/ml, p< 0/0001. Increased age, Increased LA size and high plasma level of ProBNP were associated with increased risk for post op AF. After adjustment of risk factors, plasma level of ProBNP was the most important risk factor with odds ratio of 15.34 with CI 95% 1.77-132.95 and then LA diameter with odds ratio of 6.11 with CI 95% 0.99-37.42 was independently correlated with post op AF. Correlation between plasma level of ProBNP with age and LA size was seen too (LA size r = 0.0281, p= 0.012. Between age and ProBNP (r= 0.337, p= 0.002. The best cut off point for plasma ProBNP as a predictor of post op AF was 854 pg/ml."n "nConclusion: Increased level of preoperative ProBNP levels could be an independent predictor of post operative Atrial Fibrillation.

  19. How do Patients Experience Consultations in an Outpatient AF-clinic?

    DEFF Research Database (Denmark)

    Thrysøe, Lars

    at Odense University Hospital, Denmark, was established marts 2012, and has in order to qualify patient treatment and care. The aim of the current project is to evaluate the clinic. Purpose / research questions How do patient and relatives experience consultations in AF-clinic? (Phase I) How do QoL develop......, but they did not talk about their fear during the consultations - neither by physician nor by nurse. In the following consultations with nurses, focus was on living with and consequences of AF. For some patients, it was a surprise that the following consultations were by nurses. Relatives, when present, were...

  20. Fremlæggelse af projekt med Epworth søvnighedsskema, opgørelse af data fra 2009-2014: "Prevalence of excessive daytime sleepiness in patients treated with orthognathic surgery"

    DEFF Research Database (Denmark)

    Linderup, Mette Werner

    Fremlæggelse af projekt med Epworth søvnighedsskema, opgørelse af data fra 2009-2014: "Prevalence of excessive daytime sleepiness in patients treated with orthognathic surgery"......Fremlæggelse af projekt med Epworth søvnighedsskema, opgørelse af data fra 2009-2014: "Prevalence of excessive daytime sleepiness in patients treated with orthognathic surgery"...

  1. The RecordAF study: design, baseline data, and profile of patients according to chosen treatment strategy for atrial fibrillation

    DEFF Research Database (Denmark)

    Le Heuzey, Jean-Yves; Breithardt, Günter; Camm, John

    2010-01-01

    to patients receiving a rate-control strategy. A rate-control strategy was more common in patients with a history of heart failure or valvular heart disease and persistent AF. Rate-control patients more often had previous electrocardiographic evidence of AF and were not in sinus rhythm at inclusion (p...

  2. Meningsfuld telemedicinsk hjemmemonitorering for både klinikere og patienter skabes gennem forhandling og involvering

    DEFF Research Database (Denmark)

    Petersen, Olav Bjørn; Rasch, Sarah Maria; Bach, Katrine

    Baggrund og motivation Behandling og monitorering af patienter og borgere gennem telemedicin struktureres som udgangspunkt efter klinisk viden, organisatoriske arbejdsgange, vagtplaner, eksisterende ambulant praksis samt tekniske muligheder. I tillæg overføres størstedelen af patienters målinger...... patienter på. Og vi peger på betydningen af samarbejde/forhandling i udvikling og implementering af telemedicin. Beskrivelse I tilknytning til projektet Klinisk Integreret Hjemmemonitorering (KIH) er der gennemført en kvalitativ evaluering, hvor delprojektet om komplicerede graviditeter omfattede 100......, meningsfulde systemer for klinikere og patienter bør baseres på såvel borgernes dagligdag som klinisk viden og organisatorisk optimering. Baseret på evaluering af vores case argumenterer vi for, at den sikreste løsning på nuværende tidspunkt er, at tilpasse løsninger til patienternes dagsrytme, så de gravide...

  3. Ud af Napoli:I en flodstrøm af kvindelig skrift beretter Elena Ferrante om to veninders kamp med fattigdom, mænd, børn, skrift og hinanden.

    OpenAIRE

    Lausten, Pia Schwarz

    2016-01-01

    Artiklen præsenterer Elena Ferrantes romankvartet "Min geniale veninde" (2011-14). Indledningen behandler problemstillingen vedrørende forfatterens fortsatte ønske om at være anonym, hvorefter artiklen analyserer værket ud fra genremæssige, sproglige og tematiske kriterier. Artiklen er bygget op om analyser af den sociale tematik, af venindeforholdet og det kvindelige, af romanernes metanarrative lag, og endelig af den poetik, værket giver udtryk for.

  4. Selvstyring af peroral antikoagulationsbehandling hos patienter med kunstige hjerteklapper

    DEFF Research Database (Denmark)

    Hasenkam, J. Michael; Kimose, H H; Grønnesby, H;

    1998-01-01

    Twenty-one heart valve operated patients (age 19-70 years) were trained in self-managed oral anticoagulant therapy using a home coagulometer (CoaguChek). Twenty patients accomplished between eight and 29 (median 24) months of self management and were fully capable of self management after 30 weeks....... All self-managing patients had their median INR-value within the therapeutic range, versus only 14 in the control group. Self-management of oral anticoagulant therapy seems feasible for selected patients. Udgivelsesdato: 1998-Nov-16...... of training. No patients experienced major bleeds or thrombo-embolic events. A control group of 20 patients from our department was matched, retrospectively, to the study group. The self-managing patients were within the therapeutic INR range 78% of the study period compared to 54% for the control patients...

  5. Relevansen af nyere psykodynamisk teori for det klinisk musikterapeutiske arbejde med psykiatriske patienter med personlighedsforstyrrelser

    DEFF Research Database (Denmark)

    Hannibal, Niels

    2007-01-01

    Denne artikel beskriver et rationale for anvendelse af musik i en psykoterapeutisk kontekst. Det eksplicitte og implicitte forandringsniveau i psykoterapi med patienter med borderline-personlighedsforstyrrelse (BPF) diskuteres herpå med henvisning til to forskellige syn på terapeutisk forandring...

  6. Kliniske retningslinjer for træning af aerob kapacitet og muskelstyrke til patienter med reumatoid artrit

    DEFF Research Database (Denmark)

    Larsen, Birgit Tine; Læssøe, Uffe; Kjær, Thomas;

    reumatoid artrit. Kortvarig landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes itræningen af patienter med reumatoid artrit. Længerevarende landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes itræningen af patienter med reumatoid artrit......-intensitets træning af patienter med reumatoid artrit. Evidensen forsikkerhed og effekt af høj-intensitetstræning af patienter med reumatoid artrit i funktionsklasse III er CENTER FOR KLINISKE RETNINGSLINJER- CLEARINGHOUSESide 2uklar. Der bør derfor tages ekstra forholdsregler i forbindelse med træningen af disse...... forstærker denne risiko. Formål: Gennem effektiv og sikker træning at øge RA patienters aerob kapacitet og muskel styrke for dermed atlette patienternes daglige aktiviteter. Patienter: Voksne patienter (> 18 år) med diagnosen reumatoid artrit ifølge ARA eller ACR/EULAR kriterierne,funktionsklasserne I, II og...

  7. Ultralydsskanning af lungerne hos den kritisk syge patient

    DEFF Research Database (Denmark)

    Jepsen, Søren Vad; Christiansen, Aage; Sloth, Erik

    2009-01-01

    Lung sonography is an old technique applied in a new fashion. Applying lung sonography in the examination of an acute patient with pulmonary problems is a novelty in Denmark. Applications, limitations, techniques, equipment and general principles for lung sonography are reviewed. We introduce...... the "typical signs" such as lung sliding and artefacts. The rationale for lung ultrasonography in the treatment of acute patients seems obvious when comparing this technique with conventional diagnostic tools for the diagnosis of pulmonary status. Udgivelsesdato: 2009-Aug-31...

  8. Implantable loop recorder monitoring after concomitant surgical ablation for atrial fibrillation (AF): insights from more than 200 continuously monitored patients.

    Science.gov (United States)

    Pecha, Simon; Aydin, Muhammet Ali; Ahmadzade, Teymour; Hartel, Friederike; Hoffmann, Boris; Steven, Daniel; Willems, Stephan; Reichenspurner, Hermann; Wagner, Florian Mathias

    2016-08-01

    Different follow-up methods have been used to report success rates after AF ablation. Recent studies have shown that intermittent rhythm monitoring underestimates the actual AF recurrence rate. We therefore report our experience with continuous rhythm monitoring by implantable loop recorder (ILR) in a large patient cohort. Between 09/2008 and 12/2012, 343 cardiac surgical patients underwent concomitant surgical AF ablation. ILR implantation was performed in 206 patients. ILR interrogation was accomplished at 3, 6 and 12 months postoperatively. Successful ablation was defined as AF Burden <0.5 %. Primary outcome of the study was freedom from AF at 12-month follow-up. Mean patient's age was 70.5 ± 7.4 years. No major ablation- or ILR-related complications occurred. In 4 patients (1.9 %) ILR had to be explanted due to ILR-related wound infection (n = 2) or chronic pain (n = 2). Survival rate at 1-year follow-up was 96.6 %. Freedom from AF rate after 1-year follow-up was 68.5 and 63.6 % off antiarrhythmic drugs, respectively. Statistically significant predictors for successful ablation at 1-year follow-up were smaller LA diameter, shorter duration of AF and preoperative paroxysmal AF. Demographic data, indication for surgery, lesion set and used energy source had no impact on freedom from AF after 1 year. Continuous ILR monitoring after concomitant surgical AF ablation was safe and feasible, with registered freedom from AF rate of 68.5 % at 1-year follow-up. Thus continuous rhythm monitoring provides reliable outcome data and helps to guide antiarrhythmic therapy.

  9. Lektorkvalificering ved lærerseminarier i faget Musik 1992 – 2004
- samt en diskussion af professionsbegrebet. (2005)

    DEFF Research Database (Denmark)

    Lembcke, Steen

    2005-01-01

    Undersøgelsen tegner et billede af den faglig pædagogiske profil hos den musiklærergruppe der i dag varetager professionsbacheloruddannelsen af musiklærere til folkeskolen.Gennem analyse af 6 fokusområder behandles lærergruppens rekrutteringsveje, erfaringshorisont inden for musikundervisning af...... børn og unge, graden af specialisering og efteruddannelse m.m.Samtidig giver undersøgelsen anledning til en analyse af udviklingen inden for de mellemlange videregående uddannelser i retning af professionsbacheloruddannelser samt diskuterer professionsbegrebet....

  10. Præoperativ vurdering af patienter med hypertension

    DEFF Research Database (Denmark)

    Smitt, Margit; Lind, Morten Nikolaj

    2012-01-01

    Almost one out of four patients referred for non cardiac surgery presents preoperatively with hypertensio arterialis (HA). The risk of perioperative cardiovascular complication increases with the grade of HA and the coexistence of end organ damage. This paper is a review of the current knowledge...

  11. Laparoskopi af 100 konsekutive patienter med 128 ikkepalpable testes

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lenz, K

    1996-01-01

    . No intratubular germ cell neoplasia (carcinoma in situ) was proved. Germ cell hypoplasia or aplasia was demonstrated in 95% of cases with testicular parenchyma. We recommend laparoscopy as a safe procedure which leads to a diagnosis in patients with impalpable testes; the advent of laparoscopic procedure makes...

  12. Udvikling af sklerodermisk krise hos patient med uerkendt sklerodermi

    DEFF Research Database (Denmark)

    Madsen, Kristine Lindhard; Hansen, Alastair; Halberg, Poul;

    2014-01-01

    Less than 10% of the patients with systemic scleroderma develop renal crisis, i.e. acute renal failure and severe hypertension in most cases. Kidney biopsy shows hypertensive arteriolar changes. This complication was lethal until treatment with captopril was introduced in 1976. Since that time...

  13. Hurtig identifikation af patienter med neutropeni og feber bedrer prognosen

    DEFF Research Database (Denmark)

    Johansson, Sofia; Jensen, Lars Henrik

    2015-01-01

    The purpose of this article is to describe the management of febrile neutropenia in the medical emergency room. Symptoms and signs of inflammation in patients receiving chemotherapy may be blunted or absent and fever may be the only sign of severe infection. Early initiation of empirical...

  14. The RecordAF study: design, baseline data, and profile of patients according to chosen treatment strategy for atrial fibrillation

    DEFF Research Database (Denmark)

    Le Heuzey, Jean-Yves; Breithardt, Günter; Camm, John;

    2010-01-01

    The REgistry on Cardiac rhythm disORDers assessing the control of Atrial Fibrillation (RecordAF) is the first worldwide, 1-year observational, longitudinal study of the management of paroxysmal/persistent atrial fibrillation (AF) in recently diagnosed patients. The study was conducted at 532 site...

  15. Medicinsk behandling af vandladningsproblemer hos mænd

    DEFF Research Database (Denmark)

    Andersen, Jens Thorup; Nordling, Jørgen; Walter, Steen

    2007-01-01

    Lower Urinary Tract Symptoms (LUTS) e.g. in prostatic infravesical obstruction and symptoms of overactive bladder (OAB) in men can be treated effectively with drugs. The current evidence for use of alpha-adrenergic blocking agents, 5-alpha-reductase inhibitors, combination therapy and antimuscari...... by the administration of a loop-diuretic in the late afternoon. Udgivelsesdato: 2007-May-14...

  16. Tiotropium. Nyt antikolinergikum til behandling af kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Pedersen, Steffen Thirstrup; Lange, Peter

    2003-01-01

    Tiotropium is a new anti-cholinergic drug with a long duration of action designed for maintenance treatment of chronic obstructive pulmonary disease (COPD). Tiotropium is the first drug specifically developed for the treatment of COPD, but it is also amongst the most expensive drugs used for this......Tiotropium is a new anti-cholinergic drug with a long duration of action designed for maintenance treatment of chronic obstructive pulmonary disease (COPD). Tiotropium is the first drug specifically developed for the treatment of COPD, but it is also amongst the most expensive drugs used...

  17. Antibiotika som primær behandling af appendicitis

    DEFF Research Database (Denmark)

    Hupfeld, Line; Pommergaard, Hans-Christian; Burcharth, Jakob;

    2014-01-01

    Acute appendicitis has traditionally been treated surgically. Conservative approach with antibiotic treatment has been suggested as an alternative to the surgical procedure. The available studies on surgery versus antibiotics may indicate the safe use of conservative treatment for uncomplicated...... appendicitis, but the available studies are typically of low quality. Thus, further studies are needed to clarify the role of conservative treatment, and in the meantime appendectomy remains the standard treatment for acute appendicitis....

  18. Laktatacidose ved behandling af type 2-diabetes med metformin

    DEFF Research Database (Denmark)

    Holst, Helle; Eldrup, Ebbe; Guldstad, Nana Harriet;

    2012-01-01

    Metformin (MET) is the first-line agent in treatment of type 2 diabetes. However, MET has been associated with lactic acidosis (MALA), a potential but rare complication which has influenced treatment strategies in decades. Recently, guidelines have been changed in regards of age and heart failure...

  19. Behandling af pilonidalcyster med neodynium-yttriumaluminiumgranat-laser

    DEFF Research Database (Denmark)

    Lindholt, Christine S; Lindholt, Jes Sanddal; Lindholt, Jan

    2008-01-01

    A 23 year-old woman with a nonsupporative pilonidal cyst was successfully treated causally with Nd-YAG laser, and without any recidivate after 9 months follow-up. The mechanism is presumed to be that YAG-laser has a wave-length of 1064 nm. Consequently, the wave penetration through the skin is de...... is deeper than most other lasers before the energy is absorbed in melanin and oxyhaemoglobin, so the contents of the cyst can be reached and destroyed. The treatment could be a very attractive alternative to open surgery....

  20. Behandling af pilonidalcyster med neodynium-yttriumaluminiumgranat-laser

    DEFF Research Database (Denmark)

    Lindholt, Christine S; Lindholt, Jes S; Lindholt, Jan

    2008-01-01

    A 23 year-old woman with a nonsupporative pilonidal cyst was successfully treated causally with Nd-YAG laser, and without any recidivate after 9 months follow-up. The mechanism is presumed to be that YAG-laser has a wave-length of 1064 nm. Consequently, the wave penetration through the skin is de...... is deeper than most other lasers before the energy is absorbed in melanin and oxyhaemoglobin, so the contents of the cyst can be reached and destroyed. The treatment could be a very attractive alternative to open surgery. Udgivelsesdato: 2008-Jun-23...

  1. Kirurgisk behandling af fedme hos børn

    DEFF Research Database (Denmark)

    Hansen, Ann Berit; Gögenur, Ismail; Støckel, Mikael

    2014-01-01

    Morbid obesity in teenagers has become an increasing problem. Conventional diet has not yet shown effective long-term weight loss. Alternatively, bariatric surgery on adolescents has resulted in substantial weight loss, recovery from diabetes, improvement of cardiovascular risk factors...... and improvement in psychosocial status. Still, surgery performed on adolescents provides ethical challenges such as the unknown long-term prognosis after surgery. Despite these challenges, in cases of severe intractable obesity or development of life-threatening complications due to obesity, surgery should...

  2. Diagnose og behandling af cerebral venøs sinustrombose

    DEFF Research Database (Denmark)

    Birkeland, Peter; Stilling, Margit Vejen; Høgedal, Lisbeth

    2015-01-01

    antagonists for three months or more. In fulminant cases local thrombolysis is administered, while symptomatic treatment for increased intracranial pressure is given. In retrospective analyses this approach has been associated with a good outcome – even in cases treated by decompressive craniectomy....

  3. Tyndtarmstransplantation som behandling af tarmsvigt hos børn

    DEFF Research Database (Denmark)

    Thøstesen, Lisbeth Marianne; Qvist, Niels; Rasmussen, Allan

    2010-01-01

    Parenteral nutrition is the main treatment of intestinal failure. In cases with irreversible intestinal failure and life-threatening complications to parenteral nutritional treatment, transplantation of the intestine may be considered. Post-transplantation survival has increased markedly during...

  4. Ranolazin--ny behandling af kronisk stabil angina pectoris

    DEFF Research Database (Denmark)

    Ahlehoff, Ole; Hansen, Peter Riis

    2009-01-01

    Ranolazine sustained-release tablets were recently approved in the EU for chronic stable angina as add-on therapy when symptoms are not controlled with first-line agents. The mechanism of action is thought to involve inhibition of late sodium influx in the heart, which can reduce abnormalities...... of contractility and repolarisation associated with ischaemia. Ranolazine increases the exercise capacity, reduces angina, and diminishes the use of nitroglycerine. The drug has an excellent safety profile and may be a valuable addition to the treatment of chronic stable angina....

  5. Medicinsk behandling af små abdominale aortaaneurismer

    DEFF Research Database (Denmark)

    Høgh, Annette Langager; Sandermann, Jes; Lindholt, Jes S

    2008-01-01

    such as prevention for cardiovascular disease has a spin-off benefit by suppressing the expansion rate of AAAs. According to these studies ACE inhibitors, statins and nonsteroidal anti-inflammatory drugs may have effect, macrolides may have some effect while beta-blockers and calcium-channel blockers have no effect...

  6. Udredning og behandling af osteoporose ved cancer mammae uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Kristensen, Bent; Langdahl, Bente Lomholt;

    2011-01-01

    The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer....

  7. Osteoporosens betydning for behandling af frakturer og ortopaediske muligheder

    DEFF Research Database (Denmark)

    Lauritzen, J B

    2001-01-01

    The treatment of osteoporosis-related fractures can be difficult, when secure fixation and stable osteosynthesis is obtained in frail trabecular and cortical bone. In the case of defects, bone grafting and substitutes may be needed to reinforce osteosynthesis and promote fracture healing, which may......, intramedullary nails with neck screw, retrograde intramedullary nails, external fixation, cannulated screws, various plates, tension band wiring, threaded K-pins, and to some extent arthroplasties and reconstructive spine instrumentation. The goal in the treatment of osteoporosis-related fractures is to restore...... be delayed. The structural grafts may be biologically inert or osteoconductive, but also osteoinductive, and various osteoinductive growth factors and hormones could be a supplement to treatment. Several types of osteosyntheses have improved the clinical outcome, among them: sliding hip screw, neck screws...

  8. Vellykket konservativ behandling af chylopericardium efter koronar bypassoperation

    DEFF Research Database (Denmark)

    Clausen, Jesper Holmbæck; Veien, Karsten Tange

    2012-01-01

    Chylopericardium after thoracic duct injury is a rare but serious complication of thoracic surgery with mortality rates above 50% without intervention. Complications of chylopericardium are malnutrition, immunosuppression, electrolyte derangement and tamponade. This case describes a 67-year...

  9. Medicinsk behandling af små abdominale aortaaneurismer

    DEFF Research Database (Denmark)

    Høgh, Annette Langager; Sandermann, Jes; Lindholt, Jes Sanddal

    2008-01-01

    Our expectation is that the numbers of diagnosed small abdominal aortic aneurysms (AAA) will increase in the future. Slowing down the progression of AAAs is of great interest as this could prevent cost-intensive and potential lethal operations. Recent studies indicate that modern medical treatment...

  10. Intranasal glukagon til behandling af hypoglykaemi. En fremtidig behandlingsmulighed

    DEFF Research Database (Denmark)

    Carstens, S; Andersen, I; Gustafsson, Ida

    1994-01-01

    or glucose administered intravenously by a physician. These are however not optimal treatments. Obtaining intravenous access requires a medical doctor and glucagon injection is not always properly done by family members. Glucagon administered intranasally has been proven to raise blood glucose levels...... in volunteers. The effect of intranasal glucagon on blood glucose is similar to that seen after intramuscular administration for the first 15 minutes following administration. However, intranasal glucagon seems more physiological in that is stabilizes blood glucose concentrations at nearfasting levels, whereas...... glucagon given intramuscularly tends to give hyperglycaemia. Intranasal glucagon is easy to administer, and can thus prevent serious hypoglycaemic crises and thereby make diabetics and their families more secure....

  11. Udredning og behandling af osteoporose ved cancer mammae uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia A; Hansen, Mogens; Kristensen, Bent;

    2011-01-01

    The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer.......The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer....

  12. Narrativ og evidensbaseret behandling af komplekst traumatiserede mennesker

    DEFF Research Database (Denmark)

    Riber, Karin; Lindvig, Ditte

    2011-01-01

    Many survivors of potentially traumatizing events develop serious psychological problems. This article aims to critically examine two fundamentally different treatment paradigms. The article presents and discusses Michael White's narrative therapy, Metin Basoglu's modified behaviour therapy...... and Frank Neuners narrative exposure therapy in the hope that a resource focused exchange between these different theoretical and practical fields can enrich the psychological treatment of complex traumatized individuals. By comparing the respective perspectives, they are brought into a dialogue...... that results in building a bridge between narrative and evidence based theories and their practices....

  13. Kirurgisk behandling af anale fistler ved Crohns sygdom

    DEFF Research Database (Denmark)

    Heyckendorff-Diebold, Tina; Maeda, Yasuko; Buntzen, Steen;

    2012-01-01

    The treatment of transsphincteric anal fistulas in Crohn's disease is a balance between the elimination of the sepsis and the functional outcome. Loose setons can be used as a preoperative drainage or chronic treatment. Fibrin glue and the anal fistula plug are methods with excellent functional...... outcomes, but the success rate varies. The endorectal advancement flap is considered to be the gold standard. Ligation of the intersphincteric fistula tract is promising. Proctectomy or proctocolectomy in combination with transposition flaps may be necessary. A success rate of 66-70% has been reported....

  14. Fotodynamisk behandling af kolangiokarcinom hos 80-årig

    DEFF Research Database (Denmark)

    Ulstrup, Thomas; Pedersen, Finn Møller

    2013-01-01

    70% of cholangiocarcinomas (CC) are perihilar lesions. At the time of diagnosis few are candidates for complete resection, and the standard palliative therapy has been biliary stenting. Studies have shown that photodynamic therapy (PDT) improves survival time. In this case report we describe an 8...

  15. Årsager, udredning og behandling af abortus habitualis

    DEFF Research Database (Denmark)

    Larsen, Elisabeth Clare; Christiansen, Ole Bjarne

    2012-01-01

    Recurrent miscarriage (RM) is defined as three or more consecutive early pregnancy losses and affects 1% of couples. RM is probably a multifactorial disease and evaluation includes parental karyotyping, testing for uterine anomalies, thyroid dysfunction, thrombophilia and immune factors. Couples...

  16. Endovenøs termisk behandling af varicer i underekstremiteterne

    DEFF Research Database (Denmark)

    Bækgaard, Niels; Schroeder, Torben V

    2011-01-01

    Using a systematic review process, we identified 15 randomised controlled trials comparing either of the two endovenous thermal techniques, radiofrequency or laser ablation, with conventional open surgery for great saphenous varicose veins. The majority of trials were small and had short-term fol...

  17. Behandling af mani hos voksne (Treatment of mania in adults)

    DEFF Research Database (Denmark)

    Licht, Rasmus Wentzer; Straszek, Sune Puggaard Vogt

    2014-01-01

    Around 1% of the population will experience at least one episode of mania. Mania has negative social consequences, may lead to cognitive impairment and may even be lethal. Therefore, prompt and efficient medical action needs to be taken, not only addressing the acute symptoms but also the high ri...... of recurrence. Many well-documented antimanic drugs are at hand, and the database has been carefully outlined in recent guidelines, also addressing factors of importance in choosing among the options. The real challenge is dealing with non-response, where the database is extremely poor....

  18. Edoxaban versus enoxaparin-warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF)

    DEFF Research Database (Denmark)

    Goette, Andreas; Merino, Jose L; Ezekowitz, Michael D;

    2016-01-01

    ·48, 95% CI 0·64-3·55). The results were independent of the TEE-guided strategy and anticoagulation status. INTERPRETATION: ENSURE-AF is the largest prospective randomised clinical trial of anticoagulation for cardioversion of patients with non-valvular atrial fibrillation. Rates of major and CRNM...... bleeding and thromboembolism were low in the two treatment groups. FUNDING: Daiichi Sankyo provided financial support for the study....

  19. Kliniske retningslinjer for træning af aerob kapacitet og muskelstyrke til patienter med reumatoid artrit

    DEFF Research Database (Denmark)

    Larsen, Birgit Tine; Læssøe, Uffe; Kjær, Thomas;

    2016-01-01

    Titel Kliniske retningslinjer for træning af aerob kapacitet og muskelstyrke til patienter med reumatoid artrit Baggrund Patienter med reumatoid artrit har en forhøjet risiko for udviklingen af cardio-vaskulære lidelser (CVD) og tidlig død. Inflammation, smerter og generel træthed resulterer i...... patienter (> 18 år) med diagnosen reumatoid artrit ifølge ARA eller ACR/EULAR kriterierne, funktionsklasserne I, II og III, i primær eller sekundær sektoren. Intervention/er Kortvarig land- eller vandbaseret højintensitets træning af aerob kapacitet, kortvarig eller længerevarende land-baseret høj...... ↑ Kortvarig land-og vandbaseret højintensitets træning af aerob kapacitet bør overvejes i træningen af patienter med reumatoid artrit. ↑ Kortvarig landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes i træningen af patienter med reumatoid artrit. ↑ Længerevarende landbaseret...

  20. ROCKET AF adds more concerns about Digoxin safety in patients with atrial fibrillation.

    Science.gov (United States)

    ElMaghawry, Mohamed

    2015-01-01

    In a recent article in the Journal, we have reviewed the adverse cardiovascular outcomes observed with digoxin use in the PALLAS study.(1) The PALLAS study was designed to determine if dronedarone would reduce major vascular events in patients with permanent atrial fibrillation (AF).(2) However the study was stopped early because of safety reasons, as a significant number of patients on the dronedarone arm reached the co-primary end point composite of stroke, myocardial infarction, systemic embolism, or cardiovascular death. Data sub-analyses suggested that digoxin-dronedarone interaction was responsible for the higher arrhythmic death rate observed in the trial. These observations are consistent with several other studies that demonstrate the potential hazard of the use of digoxin in heart failure and/or atrial fibrillation. A more recent article published in the Lancet studied the use and outcomes of digoxin in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism in Atrial Fibrillation (ROCKET AF) trial.(3) The investigators concluded that digoxin treatment was associated with a significant increase in all-cause mortality, vascular death, and sudden death in patients with AF.

  1. Implementering af ny standard for forebyggelse af delir i forhold til ældre svagelige patienter > 65 år med hoftefraktur

    DEFF Research Database (Denmark)

    Bagger, Bettan; Rehder, Bente; Pedersen, Niels

    2013-01-01

    at identificere best evidence i forhold til brug af screeningsredskaber. På baggrund af det systematiske review er der udviklet en ny evidensbaseret instruks. Der er planlagt og afholdt undervisningssessioner af afdelingens personale i forhold til dokumentation samt vigtigheden af nasal ilt og inddragelse af de...

  2. Natriuretic peptides for the detection of paroxysmal atrial fibrillation in patients with cerebral ischemia--the Find-AF study.

    Directory of Open Access Journals (Sweden)

    Rolf Wachter

    Full Text Available BACKGROUND AND PURPOSE: Diagnosis of paroxysmal atrial fibrillation (AF can be challenging, but it is highly relevant in patients presenting with sinus rhythm and acute cerebral ischemia. We aimed to evaluate prospectively whether natriuretic peptide levels and kinetics identify patients with paroxysmal AF. METHODS: Patients with acute cerebral ischemia were included into the prospective observational Find-AF study. N-terminal pro brain-type natriuretic peptide (NT-proBNP, brain-type natriuretic peptide (BNP and N-terminal pro atrial-type natriuretic peptide (NT-proANP plasma levels were measured on admission, after 6 and 24 hours. Patients free from AF at presentation received 7 day Holter monitoring. We prospectively hypothesized that patients presenting in sinus rhythm with NT-proBNP>median were more likely to have paroxysmal AF than patients with NT-proBNPmedian (239 pg/ml, 17.9% had paroxysmal AF in contrast to 7.4% with NT-proBNP<239 pg/ml (p = 0.025. The ratio of early (0 h to late (24 h plasma levels of NT-proBNP showed no difference between both groups. For the detection of paroxysmal atrial fibrillation, BNP, NT-proBNP and NT-proANP at admission had an area under the curve in ROC analysis of 0.747 (0.663-0.831, 0.638 (0.531-0.744 and 0.663 (0.566-0.761, respectively. In multivariate analysis, BNP was the only biomarker to be independently predictive for paroxysmal atrial fibrillation. CONCLUSIONS: BNP is independently predictive of paroxysmal AF detected by prolonged ECG monitoring in patients with cerebral ischemia and may be used to effectively select patients for prolonged Holter monitoring.

  3. Forekomst af afvigende isbjørne i Østgrønland

    DEFF Research Database (Denmark)

    Dietz, R.; Sonne, Christian; Born, E. W.

    I de seneste år har der været øget fokus på de mulige miljømæssige virkninger af de såkaldte persistente organisk forurenende stoffer i Arktis som f.eks DDT og PCB. Denne rapport behandler indsamlede oplysninger fra de østgrønlandske isbjørnejægere om forekomsten af isbjørne, her især forekomsten...

  4. Medicinsk teknologivurdering af akupunktur til gravide

    DEFF Research Database (Denmark)

    Feenstra, Maria Monberg; Johansen, Marianne; Sørensen, Lisbeth Falborg;

    -, organisatorisk- og økonomisk perspektiv. Metode: Der blev udarbejdet en medicinsk teknologivurdering (MTV). En alsidig og systematisk litteraturgennemgang af akupunkturbehandling til gravide med emesis/hyperemesis gravidarum, bækkenrelaterede smerter eller depression/angst blev udført. Den udvalgte litteratur...... behandlingen udføres korrekt af TCM-uddannet sundhedspersonale. Undersøgelser har vist høj patienttilfredshed blandt gravide ved akupunkturbehandling. Økonomiske beregninger dokumenterer, at akupunktur er et billigt behandlingstilbud. Konsekvenser for praksis: Det anbefales, at tilbyde gravide med emesis/hyperemesis...... gravidarum akupunkturbehandling. Udvalgt sundhedspersonale skal uddannes til at give behandlingen, og der bør tilstræbes kontinuitet i behandlingsforløbet. Yderligere studier, der undersøger evidensen for behandling af bækkenrelaterede smerter og depression/angst med akupunktur, anbefales....

  5. Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial

    Science.gov (United States)

    Steinberg, Benjamin A.; Hellkamp, Anne S.; Lokhnygina, Yuliya; Patel, Manesh R.; Breithardt, Günter; Hankey, Graeme J.; Becker, Richard C.; Singer, Daniel E.; Halperin, Jonathan L.; Hacke, Werner; Nessel, Christopher C.; Berkowitz, Scott D.; Mahaffey, Kenneth W.; Fox, Keith A.A.; Califf, Robert M.; Piccini, Jonathan P.

    2015-01-01

    Aim Anticoagulation prophylaxis for stroke is recommended for at-risk patients with either persistent or paroxysmal atrial fibrillation (AF). We compared outcomes in patients with persistent vs. paroxysmal AF receiving oral anticoagulation. Methods and results Patients randomized in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET-AF) trial (n = 14 264) were grouped by baseline AF category: paroxysmal or persistent. Multivariable adjustment was performed to compare thrombo-embolic events, bleeding, and death between groups, in high-risk subgroups, and across treatment assignment (rivaroxaban or warfarin). Of 14 062 patients, 11 548 (82%) had persistent AF and 2514 (18%) had paroxysmal AF. Patients with persistent AF were marginally older (73 vs. 72, P = 0.03), less likely female (39 vs. 45%, P < 0.0001), and more likely to have previously used vitamin K antagonists (64 vs. 56%, P < 0.0001) compared with patients with paroxysmal AF. In patients randomized to warfarin, time in therapeutic range was similar (58 vs. 57%, P = 0.94). Patients with persistent AF had higher adjusted rates of stroke or systemic embolism (2.18 vs. 1.73 events per 100-patient-years, P = 0.048) and all-cause mortality (4.78 vs. 3.52, P = 0.006). Rates of major bleeding were similar (3.55 vs. 3.31, P = 0.77). Rates of stroke or systemic embolism in both types of AF did not differ by treatment assignment (rivaroxaban vs. warfarin, Pinteraction = 0.6). Conclusion In patients with AF at moderate-to-high risk of stroke receiving anticoagulation, those with persistent AF have a higher risk of thrombo-embolic events and worse survival compared with paroxysmal AF. PMID:25209598

  6. New-onset atrial fibrillation after acute myocardial infarction in patients with left ventricular systolic dysfunction recorded by an Implantable Cardiac Monitor - Incidence, prediction and prognosis

    DEFF Research Database (Denmark)

    Jøns, Christian

    2010-01-01

    , med høj præcision, identificeres tidligt after AMI vha. metoder, der er følsomme for abnorm kardiel autonomon funktion. Fremtidige studier bør afklare om tidlig identificering af højrisiko-behandling samt præventiv behandling kan nedsætte den kardiovaskulære morbiditet og mortalitet i denne gruppe...

  7. Optimering af behandlingseffekten i akvakultur. Minimering af forbrug og udledning af hjælpestoffer

    DEFF Research Database (Denmark)

    Sortkjær, Ole; Henriksen, Niels Henrik; Demuth Heinecke, Rasmus;

    er 1/5 af, hvad der normalt anvendes. Brintoverilte omsættes hurtigt, så det er nødvendigt at supplere med brintoverilte under behandlingen i damme. Forsøg med biofilter viser, at formalin omsættes hurtigere, hvis det i forvejen har været eksponeret med formalin, og det skader ikke den mikrobielle...... behandlingstiden samtidig bliver forlænget, sådan som toksicitetstestene viser. For at bekæmpe fiskedræberen skal der behandles flere gange med nogle dages mellemrum, når dambruget er hårdt inficeret. I recirkulerende anlæg med biofilter er det nødvendigt at supplere med formalin for at holde koncentrationen under...

  8. Use and Outcomes of Antiarrhythmic Therapy in Patients with Atrial Fibrillation Receiving Oral Anticoagulation: Results from the ROCKET AF Trial

    Science.gov (United States)

    Steinberg, Benjamin A.; Hellkamp, Anne S.; Lokhnygina, Yuliya; Halperin, Jonathan L.; Breithardt, Günter; Passman, Rod; Hankey, Graeme J.; Patel, Manesh R.; Becker, Richard C.; Singer, Daniel E.; Hacke, Werner; Berkowitz, Scott D.; Nessel, Christopher C.; Mahaffey, Kenneth W.; Fox, Keith A.A.; Califf, Robert M.; Piccini, Jonathan P.

    2014-01-01

    Background Antiarrhythmic drugs (AAD) and anticoagulation are mainstays of atrial fibrillation (AF) treatment. Objective We aimed to study the use and outcomes of AAD therapy in anticoagulated AF patients. Methods Patients in the ROCKET AF trial (n=14,264) were grouped by AAD use at baseline: amiodarone, other AAD, or no AAD. Multivariable adjustment was performed to compare stroke, bleeding, and death across groups, as well as across treatment assignment (rivaroxaban or warfarin). Results Of 14,264 patients randomized, 1681 (11.8%) were treated with an AAD (1144 [8%] with amiodarone, 537 [3.8%] with other AADs). Amiodarone-treated patients were less-often female (38% vs. 48%), had more persistent AF (64% vs. 40%), and more concomitant heart failure (71% vs. 41%) than patients receiving other AADs. Patients receiving no AAD more closely-resembled amiodarone-treated patients. Time in therapeutic range was significantly lower in warfarin-treated patients receiving amiodarone versus no AAD (50% vs. 58%, p<0.0001). Compared with no AAD, neither amiodarone (adjusted HR 0.98, 95% CI 0.74–1.31, p=0.9) nor other AADs (adjusted HR 0.66, 95% CI 0.37–1.17, p=0.15) were associated with increased mortality. Similar results were observed for embolic and bleeding outcomes. Rivaroxaban treatment effects in patients not on an AAD were consistent with the overall trial (primary endpoint adjusted HR 0.82, 95% CI 0.68–0.98, pinteraction=0.06; safety endpoint adjusted HR 1.12, 95% CI 0.90–1.24, pinteraction=0.33). Conclusion Treatment with AADs was not associated with increased morbidity or mortality in anticoagulated patients with AF. The influence of amiodarone on outcomes in patients receiving rivaroxaban requires further study. PMID:24833235

  9. Two-year outcomes of patients with newly diagnosed atrial fibrillation: results from GARFIELD-AF

    Science.gov (United States)

    Bassand, Jean-Pierre; Accetta, Gabriele; Camm, Alan John; Cools, Frank; Fitzmaurice, David A.; Fox, Keith A.A.; Goldhaber, Samuel Z.; Goto, Shinya; Haas, Sylvia; Hacke, Werner; Kayani, Gloria; Mantovani, Lorenzo G.; Misselwitz, Frank; ten Cate, Hugo; Turpie, Alexander G.G.; Verheugt, Freek W.A.; Kakkar, Ajay K.

    2016-01-01

    Aims The relationship between outcomes and time after diagnosis for patients with non-valvular atrial fibrillation (NVAF) is poorly defined, especially beyond the first year. Methods and results GARFIELD-AF is an ongoing, global observational study of adults with newly diagnosed NVAF. Two-year outcomes of 17 162 patients prospectively enrolled in GARFIELD-AF were analysed in light of baseline characteristics, risk profiles for stroke/systemic embolism (SE), and antithrombotic therapy. The mean (standard deviation) age was 69.8 (11.4) years, 43.8% were women, and the mean CHA2DS2-VASc score was 3.3 (1.6); 60.8% of patients were prescribed anticoagulant therapy with/without antiplatelet (AP) therapy, 27.4% AP monotherapy, and 11.8% no antithrombotic therapy. At 2-year follow-up, all-cause mortality, stroke/SE, and major bleeding had occurred at a rate (95% confidence interval) of 3.83 (3.62; 4.05), 1.25 (1.13; 1.38), and 0.70 (0.62; 0.81) per 100 person-years, respectively. Rates for all three major events were highest during the first 4 months. Congestive heart failure, acute coronary syndromes, sudden/unwitnessed death, malignancy, respiratory failure, and infection/sepsis accounted for 65% of all known causes of death and strokes for <10%. Anticoagulant treatment was associated with a 35% lower risk of death. Conclusion The most frequent of the three major outcome measures was death, whose most common causes are not known to be significantly influenced by anticoagulation. This suggests that a more comprehensive approach to the management of NVAF may be needed to improve outcome. This could include, in addition to anticoagulation, interventions targeting modifiable, cause-specific risk factors for death. Clinical Trial Registration http://www.clinicaltrials.gov. Unique identifier: NCT01090362. PMID:27357359

  10. Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Qayyum, Abbas Ali; Kastrup, Jens

    2015-01-01

    The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic isch...

  11. Patients' Obligation, Embodiment, Motives, and Self in Hypertension - a Qualitative Study from General Practice (PhD thesis)

    DEFF Research Database (Denmark)

    Sångren, Henrik

    Resume: Afhandlingen besk‘ftiger sig med hvordan patienter oplever at blive diagnosticeret med forh›jet blodtryk (hypertension). Unders›gelsen unders›ger hvilke motiver der bev‘ger patienter til at acceptere medicinsk behandling af deres forh›jede blodtryk, og hvorledes de oplever livet med...... hypertension efter diagnosen. Studiet anl‘gger et patient-centret sociokulturelt syn p† risiko hvorved forskellige vinkler p† hverdagslivet med en medicinsk risikofaktor bliver synligt. Patienternes kropslige fornemmelser og biografiske erfaringer med forh›jet blodtryk bliver i afhandlingen koblet sammen med...

  12. Der mangler undersøgelser af effekten af psykologbehandling til patienter med kræft og depression

    DEFF Research Database (Denmark)

    Johnsen, Anna Thit; Ross, Lone; Guldin, Mai-Britt

    2016-01-01

    Depression is a well-known co-morbidity of cancer. A possible intervention for depression is psychological treatment defined as psychotherapy provided by a psychologist. In this narrative review we investigated the effect of psychological treatment on depression for patients with cancer. Six...... Cochrane reviews of 38 studies investigating psychological or psychosocial interventions were reviewed. One of the 38 studies could not be assessed. None of the included studies investigated psychological treatment for patients who were diagnosed with depression or included because of depression symptoms....

  13. Population pharmacokinetics and pharmacodynamics of rivaroxaban in patients with non-valvular atrial fibrillation: results from ROCKET AF.

    Science.gov (United States)

    Girgis, I G; Patel, M R; Peters, G R; Moore, K T; Mahaffey, K W; Nessel, C C; Halperin, J L; Califf, R M; Fox, K A A; Becker, R C

    2014-08-01

    Two once-daily rivaroxaban dosing regimens were compared with warfarin for stroke prevention in patients with non-valvular atrial fibrillation in ROCKET AF: 20 mg for patients with normal/mildly impaired renal function and 15 mg for patients with moderate renal impairment. Rivaroxaban population pharmacokinetic (PK)/pharmacodynamic (PD) modeling data from ROCKET AF patients (n = 161) are reported and are used to confirm established rivaroxaban PK and PK/PD models and to re-estimate values of the models' parameters for the current AF population. An oral one-compartment model with first-order absorption adequately described rivaroxaban PK. Age, renal function, and lean body mass influenced the PK model. Prothrombin time and prothrombinase-induced clotting time exhibited a near-linear relationship with rivaroxaban plasma concentration; inhibitory effects were observed through to 24 hours post-dose. Rivaroxaban plasma concentration and factor Xa activity had an inhibitory maximum-effect (Emax ) relationship. Renal function (on prothrombin time; prothrombinase-induced clotting time) and age (on factor Xa activity) had moderate effects on PK/PD models. PK and PK/PD models were shown to be adequate for describing the current dataset. These findings confirm the modeling and empirical results that led to the selection of doses tested against warfarin in ROCKET AF.

  14. U.2010 B.1; Fagforeningers kontrol af virksomheders løn- og arbejdsvilkår

    DEFF Research Database (Denmark)

    Lind, Martin Gräs

    2010-01-01

    Artiklen behandler spørgsmålet, om og i hvilket omfang fagforeninger har ret til at kontrollere især overenskomstforpligtede arbejdsgivere. Det stigende antal udenlandske arbejdstagere på det danske arbejdsmarked har medført øget fokus på og behov for kontrolførelse af overenskomstens bestemmelse......, bl.a. for at sikre mod illegal beskæftigelse, omgåelse af overenskomsterne og social dumping....

  15. Behandling af placenta percreta kræver involvering af flere specialer

    DEFF Research Database (Denmark)

    Clausen, Caroline; Lönn, Lars; Albrechtsen, Charlotte Krebs;

    2011-01-01

    Placenta percreta is a rare life-threatening obstetrical condition, often resulting in severe haemorrhage and hysterectomy. The incidence seems to be increasing, probably secondary to the increase in caesarean section rates. We present a protocol for an elective multidisciplinary approach...

  16. Systemisk prokinetisk behandling af postoperativ ileus efter abdominalkirurgi. Gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Holte, Kathrine

    2010-01-01

    Based on the evidence presented in the Cochrane review "Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults", routine administration of systemic prokinetics for the prevention of postoperative ileus is not recommendable. The potential...

  17. Behandling med dopaminagonister i den tidlige fase af Parkinsons sygdom: gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Bode, Matthias

    2009-01-01

    The Cochrane analysis confirms some well-known facts: initial therapy with dopamine agonists (DA) delays the incidence of motor complications, but is associated with inferior motor control and a higher frequency of non-motor adverse events (AE) compared with levodopa. Some serious AE are missing...

  18. Ukarakteristiske symptomer hos patienter med debut af kolorektal cancer i almen praksis

    DEFF Research Database (Denmark)

    Juul, Jakob Søgaard; Vedsted, Peter

    2012-01-01

    symptomer, og disse omfatter fx lav blodprocent, vekslende afføring, maveproblemer, træthed og vægttab. En kommende screeningskampagne vil identificere en række af disse tumorer tidligere i forløbet, men stadig skal 75 % af alle tyktarmscancere skulle diagnosticeres vha. symptomer og den praktiserende læge...

  19. Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists.

    Science.gov (United States)

    Fitzmaurice, David A; Accetta, Gabriele; Haas, Sylvia; Kayani, Gloria; Lucas Luciardi, Hector; Misselwitz, Frank; Pieper, Karen; Ten Cate, Hugo; Turpie, Alexander G G; Kakkar, Ajay K

    2016-08-01

    Vitamin K antagonist (VKA) therapy for stroke prevention in atrial fibrillation (AF) requires monitoring of the international normalized ratio (INR). We evaluated the agreement between two INR audit parameters, frequency in range (FIR) and proportion of time in the therapeutic range (TTR), using data from a global population of patients with newly diagnosed non-valvular AF, the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF). Among 17 168 patients with 1-year follow-up data available at the time of the analysis, 8445 received VKA therapy (±antiplatelet therapy) at enrolment, and of these patients, 5066 with ≥3 INR readings and for whom both FIR and TTR could be calculated were included in the analysis. In total, 70 905 INRs were analysed. At the patient level, TTR showed higher values than FIR (mean, 56·0% vs 49·8%; median, 59·7% vs 50·0%). Although patient-level FIR and TTR values were highly correlated (Pearson correlation coefficient [95% confidence interval; CI], 0·860 [0·852-0·867]), estimates from individuals showed widespread disagreement and variability (Lin's concordance coefficient [95% CI], 0·829 [0·821-0·837]). The difference between FIR and TTR explained 17·4% of the total variability of measurements. These results suggest that FIR and TTR are not equivalent and cannot be used interchangeably.

  20. Udpegning af risikolokaliteter på det tosporede vejnet i åbent land baseret på data om vejens karakteristika

    DEFF Research Database (Denmark)

    Andersen, Camilla Sloth

    registreringsgraden er siden 2001 faldet fra, at 18,5 % af de tilskadekomne, der behandles på skadestue, også blev registreret i den officielle ulykkesstatstik, til at andelen, der blev registreret i 2011, er nede på 10 %. De danske vejmyndigheder, heraf særligt kommunerne, har derfor vanskeligt ved at udpege sorte...

  1. Symptomscreening af patienter med KOL kan identificere patienter med behov for palliativ indsats

    DEFF Research Database (Denmark)

    Durakovic, Amal; Rasmussen, Dorte Lander; Kjærsgaard-Andersen, Anne Marie

    2014-01-01

    This study developed and tested a collaboration model to improve the quality of palliative care for all patients with life-threatening illness who require palliation. Journal audit was performed on 79 in-hospital patients. European Organisation for Research and Treatment of Cancer, Quality of Life...

  2. Gastropleural fistel kan behandles torakoskopisk

    DEFF Research Database (Denmark)

    Laugesen, Sofie; Nekrasas, Vytautas; Haahr, Poul Erik

    2014-01-01

    Gastropleural fistula (GPF) is although uncommon a severe and sometimes fatal complication after prior thoracic surgery, trauma or malignancy. Standard therapy has often included major surgery such as laparotomia with gastrectomi. In this case report we present a patient with GPF who underwent...

  3. Pneumocystepneumoni ved behandling med infliximab

    DEFF Research Database (Denmark)

    Josephson, Maria Eklund; Kristensen, Lena Hagelskjaer; Andersen, Vibeke

    2008-01-01

    The treatment of ulcerative colitis has improved since the appearance of Tumor Necrosis Factor (TNF)-alpha inhibitors. However, the use of TNF-alpha inhibitors increases the risk of opportunistic infections. We describe two cases of Pneumocystis jiroveci pneumonia during infliximab therapy...... for active ulcerative colitis. They were successfully treated with sulfametoxazole/trimetroprim. High awareness of P. jiroveci pneumonia in patients who develop pulmonary symptoms with hypoxia during TNF-alpha modulator therapy is recommended....

  4. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B;

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over ...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates....

  5. Behandling af akut myeloid leukæmi uden transfusion af blodprodukter hos et medlem af Jehovas Vidner

    DEFF Research Database (Denmark)

    Larsen, Christian; Jensen, Morten Krogh

    2011-01-01

    We present a case in which a young woman was diagnosed with acute myeloid leukaemia, FAB-classification type M2. As a member of Jehovah's Witnesses she refused to accept any treatment involving blood transfusions. A modified induction and consolidation chemotherapy regimen was applied, tailored...

  6. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B;

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over ...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates. Udgivelsesdato: 2009-Jun-8...

  7. Revmatoid artritt i Norge – demografi, sykdomskarakteristika og behandling. En sammenligning med andre europeiske land og USA

    Directory of Open Access Journals (Sweden)

    Glenn Haugeberg

    2012-11-01

    Full Text Available Bakgrunn: Revmatoid artritt (RA er en kronisk inflammatorisk leddsykdom som gir økt sykelighet og dødelighet. Nye biologiske legemidler har de siste 10 årene bedret prognosen betydelig. I 2005 ble QUEST-RA (Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis prosjektet etablert for å sammenligne sykdomsstatus og behandling hos RA-pasienter i forskjellige land. I denne artikkelen presenteres status for RA-pasienter i Norge sammenlignet med andre europeiske land og USA.Materiale og metode: Tilfeldig utvalgte RA-pasienter fulgt opp ved revmatologisk poliklinikk ved Sørlandet sykehus i Kristiansand (n=100 og St. Olavs Hospital i Trondheim (n=100 ble inkludert. I henhold til protokoll ble demografiske, sykdoms- og behandlingsdata registrert.Resultater: Norske RA-pasienter skilte seg lite fra gjennomsnittet i andre land med hensyn til alder, utdannelse og sykdomsvarighet. Sykdomsalvorlighet og sykdomsstatus til norske RA-pasienter er sammenlignbare med pasienter fra land som har lavest sykdomsaktivitet og best helsestatus. I Norge er andelen som behandles med biologiske legemidler ca 30%, og Norge er blant de land med størst andel pasienter som behandles med denne legemiddelgruppen. Fortolkning: RA-pasienter i Norge er blant de i Europa som har lavest sykdomsaktivitet. En årsak antas å være den relativt utbredte bruken av biologiske legemidler i Norge.

  8. LCA af genbrug af mursten

    DEFF Research Database (Denmark)

    Møller, Jacob; Damgaard, Anders; Astrup, Thomas Fruergaard

    Der er gennemført en livscyklusbaseret miljøvurdering af genbrug af mursten. Modelleringen er baseret på, hvordan Virksomheden ”Gamle Mursten” forbereder de gamle mursten med henblik på, at de kan genbruges i nybyggeri. Som alternativ til direkte genbrug nedknuses murstensaffaldet og anvendes som...

  9. Alternative Calculations of Individual Patient Time in Therapeutic Range While Taking Warfarin: Results From the ROCKET AF Trial

    Science.gov (United States)

    Singer, Daniel E.; Hellkamp, Anne S.; Yuan, Zhong; Lokhnygina, Yuliya; Patel, Manesh R.; Piccini, Jonathan P.; Hankey, Graeme J.; Breithardt, Günter; Halperin, Jonathan L.; Becker, Richard C.; Hacke, Werner; Nessel, Christopher C.; Mahaffey, Kenneth W.; Fox, Keith A. A.; Califf, Robert M.

    2015-01-01

    Background In the ROCKET AF (Rivaroxaban–Once‐daily, oral, direct Factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) trial, marked regional differences in control of warfarin anticoagulation, measured as the average individual patient time in the therapeutic range (iTTR) of the international normalized ratio (INR), were associated with longer inter‐INR test intervals. The standard Rosendaal approach can produce biased low estimates of TTR after an appropriate dose change if the follow‐up INR test interval is prolonged. We explored the effect of alternative calculations of TTR that more immediately account for dose changes on regional differences in mean iTTR in the ROCKET AF trial. Methods and Results We used an INR imputation method that accounts for dose change. We compared group mean iTTR values between our dose change–based method with the standard Rosendaal method and determined that the differences between approaches depended on the balance of dose changes that produced in‐range INRs (“corrections”) versus INRs that were out of range in the opposite direction (“overshoots”). In ROCKET AF, the overall mean iTTR of 55.2% (Rosendaal) increased up to 3.1% by using the dose change–based approach, depending on assumptions. However, large inter‐regional differences in anticoagulation control persisted. Conclusions TTR, the standard measure of control of warfarin anticoagulation, depends on imputing daily INR values for the vast majority of follow‐up days. Our TTR calculation method may better reflect the impact of warfarin dose changes than the Rosendaal approach. In the ROCKET AF trial, this dose change–based approach led to a modest increase in overall mean iTTR but did not materially affect the large inter‐regional differences previously reported. Clinical Trial Registration URL: ClinicalTrials.gov. Unique identifier: NCT00403767. PMID:25736441

  10. Rivaroxaban in the Prevention of Stroke and Systemic Embolism in Patients with Non-Valvular Atrial Fibrillation: Clinical Implications of the ROCKET AF Trial and Its Subanalyses.

    Science.gov (United States)

    Spencer, Ryan J; Amerena, John V

    2015-12-01

    Atrial fibrillation (AF) is an increasingly common cause of stroke and systemic embolism. While warfarin has been the mainstay of stroke prevention in patients with AF, newer novel oral anticoagulant medications are now available. Rivaroxaban, a direct factor Xa inhibitor with a rapid onset and offset after oral administration, offers potential advantages over warfarin, predominantly due to its predictable pharmacokinetics across wide patient populations. It requires no coagulation monitoring, and only two different doses are needed (20 mg daily for patients with normal renal function and 15 mg daily in those with reduced renal function). A large randomized trial (ROCKET AF) has shown non-inferiority to warfarin for preventing stroke or systemic embolism in the per-protocol population and superiority to warfarin in the on-treatment safety population. Several subanalyses confirm that the treatment effect of rivaroxaban is consistent across different patient subgroups, including those with reduced renal function. The tolerability of rivaroxaban appears similar to that of warfarin, with comparable overall bleeding rates in clinical trials. In ROCKET AF, significantly lower rates of fatal and intracranial bleeding were seen with rivaroxaban, while lower rates of gastrointestinal bleeding were seen with warfarin. Important contraindications to rivaroxaban include valvular AF, the presence of a prosthetic valve (mechanical or bioprosthetic) or valve repair, the need for concurrent dual antiplatelet therapy, and creatinine clearance <30 ml/min. Once-daily dosing and the lack of coagulation monitoring may increase utilization and adherence compared with warfarin, potentially decreasing the large burden of care associated with stroke secondary to AF. Overall, rivaroxaban offers a useful alternative to warfarin for stroke prevention in patients with AF.

  11. Anmeldelse af Ulrik Rammeskow Bang-Pedersen, Lasse Højlund Christensen, Kim Sommer Jensen, Christian Jul Madsen & Andreas Kærsgaard Mylin: Rekonstruktion – teori og praksis (2011)

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2011-01-01

    Artiklen anmelder det nævnte værk, som i detaljer behandler lov nr. 718 af 25. juni 2010, der indførte regler i konkursloven, som muliggør rekonstruktion af både fysiske og juridiske personer med henblik på virksomhedsoverdragelse og tvangsakkord, og således at skyldneren ikke selv kan standse re...

  12. Survival of patients with small cell lung cancer undergoing lung resection in England, 1998-2009

    DEFF Research Database (Denmark)

    Lüchtenborg, Margreet; Riaz, Sharma P; Lim, Eric

    2014-01-01

    Småcellet lungekræft behandles oftest med kemoterapi eller strålebehandling, bortset fra sygdomstilfælde på stadie et, hvor de kliniske retningslinjer anbefaler kirurgiske indgreb. Man kender dog ikke effekten af at tilbyde flere kirurgisk fjernelse af lungekræft. Ved at udnytte variationen i de ...

  13. Coaching patients to self-care: a primary responsibility of nursing

    DEFF Research Database (Denmark)

    Hørdam, Britta

    2010-01-01

    Anmelselse af international forskning:Formål: En australsk undersøgelse har fokus på aktivt at støtte og guide ældre til en rehabiliterende egenomsorg efter udskrivelse fra behandling på sygehus. Metode: Med afsæt i grounded theory udvikles en model for rehabiliterende sygepleje, hvor sygeplejers...

  14. Paclitaxels farmakogenomik hos patienter med kræft i æggestokken

    DEFF Research Database (Denmark)

    Bergmann, Troels Korshøj; Mirza, Mansoor Raza; Andersen, Charlotte Brasch;

    Formål og baggrund: Paclitaxel (Taxol®) er et kemoterapeutikum der bruges til behandling af bl.a æggestokkræft. Paclitaxel doseres individuelt (175mg/m2) men alligevel er der klinisk betydende variation i forekomsten af bivirkninger (neurotoksicitet, kvalme/opkast, knoglemarvspåvirkning m...

  15. Ud af Napoli

    DEFF Research Database (Denmark)

    Lausten, Pia Schwarz

    2016-01-01

    Artiklen præsenterer Elena Ferrantes romankvartet "Min geniale veninde" (2011-14). Indledningen behandler problemstillingen vedrørende forfatterens fortsatte ønske om at være anonym, hvorefter artiklen analyserer værket ud fra genremæssige, sproglige og tematiske kriterier. Artiklen er bygget op om...

  16. Præsentation af symptomer i almen praksis hos patienter med cancer

    DEFF Research Database (Denmark)

    Nielsen, Tine Nørgaard; Hansen, Rikke Pilegaard; Vedsted, Peter

    2010-01-01

    was 3,208 corresponding to 1.7 reported symptoms per patient. The majority (57.6%) of patients presented only one symptom. Symptoms varied with the type of cancer. Patients with breast cancer and malignant melanoma mainly presented with diagnosis-specific symptoms. Patients with colorectal, lung......INTRODUCTION: For the majority of cancer patients, the diagnostic investigations begin in general practice. The aim of the study was to investigate for which symptoms cancer patients consulted their general practitioner (GP). MATERIAL AND METHODS: All newly diagnosed cancer patients and their GPs...... in the County of Aarhus, Denmark, participated in a 1-year questionnaire survey. The GPs answered questions about the patients' first presentation of cancer symptoms and the GPs' interpretation of these symptoms. RESULTS: A total of 2,212 (83%) questionnaires were answered. The total number of reported symptoms...

  17. Hvordan påvirker brugen af trådløse telefoner kommunikationen og relationen mellem patient og sygeplejerske?

    DEFF Research Database (Denmark)

    Paasch, Bettina Sletten

    2013-01-01

    bevidst om, hvad kollegaen er i færd med, og hvorvidt man afbryder denne i en væsentlig samtale med en patient. Når telefonen ringer, skal besvarelse af opkaldet vejes op imod den konkrete situation sygeplejersken befinder sig i. Denne balance mestres generelt ikke, og opkaldet prioriteres. Når opkaldet...

  18. The Effect of Medicinal Education on Adherence Taking Warfarin in Acute Coronary Syndrome (ACS and Atrial Fibrilation (AF Patients at PKU Muhammadiyah Yogyakarta Hospital

    Directory of Open Access Journals (Sweden)

    Jastria Pusmarani

    2015-12-01

    Full Text Available In order to improve warfarin medication adherence in patient with Acute Coronary Syndrome (ACS and Atrial Fibrillation (AF, giving education with leaflet administration is one of the solutions. This study was aim to know the impact of pharmacist education with using prepared leaflet on the adherence to warfarin in ACS and AF patients. This study used pre test and post test with control group design. Data were collected prospectively during 8 weeks in June–July 2014 at the ambulatory ACS and AF patients at PKU Muhammadiyah Yogyakarta hospital, Indonesia. Data were collected by medical record and the questionnaire using Morisky Medication Adherence Scale (MMAS. Wilcoxon test was used for statistical analysis. The results shows pre test and post test value in the control group was p=0.194 and pre and post test value in the test group was p=0.058. There was no significant difference (p>0.05 after giving education with leaflet. The education with leaflet had no effect to adherence in warfarin in ACS and AF patients at PKU Muhammadiyah Yogyakarta hospital.

  19. Ambulant neuropsykologisk opfølgning af patienter indlagt med aseptisk meningitis

    DEFF Research Database (Denmark)

    Damsgaard Gunst, Jesper; Klostergaard, Kirsten Rose; Leutscher, Peter Derek Christian

    2014-01-01

    Aseptic meningitis is considered to be a benign illness with mild symptoms, and the prognosis is usually good. However, retrospective studies have demonstrated that these patients may experience cognitive sequelae. A neuropsychologist was affiliated to the Department of Infectious Diseases......, and neuropsychological findings in patients with aseptic meningitis were assessed. In conclusion, at twelve months of follow-up cognitive dysfunction persist among the majority of patients; 75% had mental fatigue and 45% had changed their work status....

  20. Interleukin-1 receptorantagonistbehandling af patienter med type 2-diabetes--sekundaerpublikation

    DEFF Research Database (Denmark)

    Larsen, Claus Morten; Faulenbach, Mirjam; Vaag, Allan

    2007-01-01

    Interleukin-1 receptor antagonist (IL-1Ra) expression is reduced in islets of patients with type 2 diabetes. 70 patients with type 2 diabetes were randomized to treatment with anakinra (IL-1Ra) or placebo for 13 weeks. Following treatment glycated hemoglobin was 0.46 percent lower, C-peptide secr......Interleukin-1 receptor antagonist (IL-1Ra) expression is reduced in islets of patients with type 2 diabetes. 70 patients with type 2 diabetes were randomized to treatment with anakinra (IL-1Ra) or placebo for 13 weeks. Following treatment glycated hemoglobin was 0.46 percent lower, C......: 2007-Nov-5...

  1. Udredning af xerostomi og hyposalivation

    DEFF Research Database (Denmark)

    Pedersen, Anne Marie Lynge; Dynesen, Anja Weirsøe; Jensen, Siri Beier

    2011-01-01

    Mundtørhed kræver grundig undersøgelse Xerostomi er ofte associeret til betydelig nedsat spytsekretion, men kan forekomme, uden at der objektivt kan påvises nedsat spytsekretion. Udredning af patienter, som klager over mundtørhed, bør således altid inkludere en omhyggelig anamnese, en detaljeret ...... adækvate behandlingsstrategier for den patient, som lider af xerostomi og nedsat spytsekretion....

  2. Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Qayyum, Abbas Ali; Kastrup, Jens

    2015-01-01

    The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic isch...

  3. Håndtering af patienter med alvorlige kroniske smerter efter lyskebrokkirurgi

    DEFF Research Database (Denmark)

    Werner, Mads U; Kehlet, Henrik

    2014-01-01

    and electrophysiological methods. Published data on 54 patients, treated with mesh removal and selective neurectomy, demonstrated that 65% patients experienced long-term reduction of pain. The PPHG unit is actively engaged in surgical and pharmacological research in order to improve treatment strategies....

  4. Visitation af patienter, som indlægges akut på mistanke om hjertesygdom

    DEFF Research Database (Denmark)

    Okkels Jensen, Lisette; Holmvang, Lene; Forberg, Jakob Lundager;

    2013-01-01

    Overall, the future emergency departments in Denmark serve as a single portal of entry for all acute patients. At the same time an expansion of prehospital diagnosing and triage will take place. In patients suspected of life-threatening cardiac conditions with specialized treatment requirements...

  5. Kombination af aliskiren og losartan hos patienter med type 2-diabetes og nefropati - Sekundaerpublikation

    DEFF Research Database (Denmark)

    Parving, Hans-Henrik; Persson, Frederik; Lewis, Julia B

    2009-01-01

    We evaluated the renoprotective effects of adding aliskiren to treatment with losartan in hypertensive patients with type 2 diabetes and nephropathy. A total of 599 patients were randomized to six months of treatment with placebo or aliskiren in addition to losartan 100 mg and optimal...

  6. 50-års-registerefterundersøgelse af 112 patienter med klassisk neurosediagnose

    DEFF Research Database (Denmark)

    Jepsen, Peter Winning; Juel, Knud; Bech, Per

    2007-01-01

    AND METHODS: The cohort consists of 112 patients (30 males (26.8%) and 82 females (73.2%)) hospitalized in the years 1952 to 1957. These patients were suffering from anxiety neuroses, obsessive-compulsive states or hysterical neuroses. In an early phase of the study, a systematic review of all records...... was made in order to re-diagnose the patients according to DSM-III. The results presented in the study are therefore mainly based on the DSM-III categories. RESULTS: The original categorization of patients into anxiety neurosis, obsessive-compulsive states or hysterical neurosis did not have any prognostic...... significance as to readmission or death. DSM-III diagnoses result in a similar picture. During follow-up a total of 67 patients died. There was a weak but insignificant excess mortality of 1.16 for men and 1.14 for women. Death by suicide was significantly increased for both sexes. Most suicides occurred...

  7. Opbygning af alliance

    DEFF Research Database (Denmark)

    Pedersen, Inge Nygaard

    2002-01-01

    Denne artikel er et forsøg på at bringe læseren med ind i atmosfæren, i oplevelsen og overvejelserne i forbindelse med opstart på et musikterapiforløb med en patient, som er meget svær at få kontakt med. Den er skrevet i et detaljerigt praksisnært sprog og har på én gang til for mål at starte på...... dokumentation af musikterapeutisk arbejde i børnepsykiatrien på musikterapiklinikken, APS og at formidle de mange facetter i et allianceopbyggende arbejde med en meget kontaktsvag patient. Artiklen beskriver prøveforløb og første del af et behandlingsforløb og er bygget op, således at praksisbeskrivelser fra...

  8. Psykoterapeutisk dagbehandling af svaert personlighedsforstyrrede patienter. En toårsopgørelse

    DEFF Research Database (Denmark)

    Christensen, Nils Balle; Toft, John; Petersen, Brian

    2007-01-01

    mutilation, suicide attempts, earlier hospitalisations and substance abuse. The most frequent diagnosis was borderline disorder 63%. There were co-morbidity with anxiety disorder 48% and depression 22%. Most importantly, we found a significant reduction in symptoms, significant increase in the level......INTRODUCTION: A psychotherapeutic day treatment (DT) for patients with severe personality disorders (PD) was established in January 2003, consisting of five months of intensive psychodynamic based integrated therapy for 14 patients. This paper presents results from the first two years. MATERIAL...... before and after therapy. The design was naturalistic. RESULTS: 40 patients (34 women) completed the DT. Eight dropped out and five received another treatment. Before treatment: Average age 27(SD 6,5), mean GAF= 43 corresponding with unemployment, singles and social dysfunctions, high degree of self...

  9. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2015-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences...... between the different types of BP no major differences were observed between BP in preventing SRE or in adverse events. Treatment with DS has in three randomised trials showed a greater effect than BP in preventing SRE. The optimal choice of bone-anti-resorptive agent should depend on the patient...

  10. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2014-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences...... between the different types of BP no major differences were observed between BP in preventing SRE or in adverse events. Treatment with DS has in three randomised trials showed a greater effect than BP in preventing SRE. The optimal choice of bone-anti-resorptive agent should depend on the patient...

  11. Øget forekomst af depression hos patienter med hepatitis C-infektion

    DEFF Research Database (Denmark)

    Hjerrild, Simon; Renvillard, Signe Groth; Leutscher, Peter Derek Christian;

    2010-01-01

    The prevalence of depression is increased in patients with chronic hepatitis C virus (HCV) infection. Several aetiological mechanisms are thought to be involved, e.g. premorbid psychiatric disease, genetic disposition to affective disorders, socio-economic factors, stigmatization and possibly HCV...... neuroinfection. Evidence to support that former intravenous drug abuse increases the risk of depression is lacking. It is particularly important to diagnose and treat depression in HCV patients as it constitutes a relative contraindication to antiviral treatment and may jeopardize therapeutic outcome....

  12. Immunmodulerende effekt af LongoVital hos patienter med recidiverende aftøs stomatit. 2

    DEFF Research Database (Denmark)

    Pedersen, A; Klausen, B; Hougen, H P

    1991-01-01

    LongoVital (LV) (DK. reg. no. 5178/75) is a herbal-based tablet enriched with recommended doses of vitamins. Peripheral lymphocyte subsets: T-helper/CD4 (OKT4+) and T-suppressor/cytotoxic/CD8 (OKT8+) were studied quantitatively in 31 otherwise healthy patients with minor recurrent aphthous...

  13. Patient med myelomatose med infiltrat på røntgen af thorax

    DEFF Research Database (Denmark)

    Schoos, Ann-Marie Malby; Steentoft, Johnna; Petersen, Michael Mørk;

    2010-01-01

    A 71-year-old man was referred to the lung department with pain in the right side of the chest through three months, especially when physically active. The patient presented with a tendency to shortness of breath, fatigue, low energy level and night sweats. The tentative diagnosis of pleural tumour...

  14. Sikkerhed af magnetisk resonans-skanning hos patienter med pacemaker og implanterbar defibrillator

    DEFF Research Database (Denmark)

    Al-Sabagh, Kifah Hekmat; Christensen, Britta Ege; Thøgersen, Anna Margrethe;

    2010-01-01

    INTRODUCTION: The presence of a cardiac implantable device is ICD considered an absolute contraindication to magnetic resonance imaging (MRI). The purpose of this study was to evaluate the safety of performing MRI in patients with cardiac pacemakers and ICDs that had a compelling clinical need...

  15. Kredsløbsmonitorering af kritisk syge patienter med "pulse contour cardiac output"-systemet

    DEFF Research Database (Denmark)

    Afshari, Arash; Perner, Anders; Bonde, Jan

    2006-01-01

    The Pulse Contour Cardiac Output (PiCCO) monitoring system measures cardiac output with high precision and accuracy. The system may replace the pulmonary artery catheter in most critically ill patients because the rate of serious complications may be lower. Whether the use of dynamic or static...

  16. Intrauterin insemination med donorsaed. Behandling af ufrivillig barnløshed på grund af mandlig infertilitet

    DEFF Research Database (Denmark)

    Vilsbøll, Tina; Helmsøe-Zinck, Lise; Andersen, A N

    1994-01-01

    of conception and expected delivery was respectively 96% and 86%. The results show that intrauterine insemination with donor semen is a good treatment for couples with male infertility. Ultrasonic measurement of the follicles and timing of hCG injection were used for optimal timing of intrauterine donor...

  17. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    Eighteen patients with stable intermittent claudication were randomized in a double blind cross-over study comparing the effects of the Ginkgo biloba extract GB-8 at a dose of 120 mg o.d. with placebo. All patients were treated for three months with the active extract and three months with placebo....... The effects of treatment on arterial insufficiency were quantified by measurements of systemic and peripheral systolic blood pressures, and pain-free and maximal walking distances on a tread-mill. Questionnaires based on visual analogue scales were used to quantify the severity of leg pain, impairment...... of concentration, and inability to remember. Short-term memory was objectively assessed. We did not find any significant changes in either peripheral blood pressures, walking distances or the severity of leg pain. Systemic blood pressure was reduced both by placebo and GB-8. The impairment of concentration...

  18. Forudsaetninger for udenlandske laegers kliniske arbejde--vurderet af dansk sundhedspersonale, patienter og udenlandske laeger

    DEFF Research Database (Denmark)

    Mitchell, A.U.; Tabaei, F.H.; Ostergaard, D.;

    2008-01-01

    INTRODUCTION: Many foreign doctors work in Danish hospitals. This study concerns the opportunities available to and difficulties encountered by these doctors. MATERIALS AND METHODS: A questionnaire concerning guidance available to foreign doctors, their linguistic and professional competence and ...... for foreign doctors, and can influence the evaluation of their professional competence. Cultural differences may influence foreign doctors' cooperation with Danish personnel. Patients are satisfied with treatment given by foreign doctors Udgivelsesdato: 2008/5/19...

  19. Restaurering af Skjern Å

    DEFF Research Database (Denmark)

    Jessen, K.; Boysen Larsen, B.; Bundgaard, P.;

    Denne rapport indeholder resultaterne af den natur- og miljøovervågning, der blev iværksat som en del af naturgenopretningen af Skjern Å 1999-2002. Ved projektet ophørte den kunstige afvanding af den vestlige del af Skjern Å dalen. Størstedelen af de dyrkede arealer ændredes til ekstensive græsni...

  20. Evalueringsrapport af projektet Musik, Sprog og Integration Søndermarkskolen, Sønderbro, Horsens 2008 til 2011

    DEFF Research Database (Denmark)

    Holst, Finn

    Den foreliggende evaluering af projektet Musik, sprog og integration, behandler et udviklingsprojekt med udvidet musikundervisning i et samarbejde mellem folkeskole og musikskole i perioden 2008 til 2011. Det er i gennem et treårigt longitudionalt studie muliggjort at udvikle viden om, hvad det er...... for kompetencer og arbejdsformer hos musiklærere og musikpædagoger, der har haft særlig betydning. Denne undersøgelse har tilknytning til, og tager afsæt i en tidligere undersøgelse af samarbejdende musikundervisning i projektet Musik til Alle, som Søndermarkskolen også har været del af. Projektet indgår som...

  1. Internationalisering af servicedesign

    DEFF Research Database (Denmark)

    Henten, Anders

    Rapporten omhandler internationaliseringen af designvirksomhede med special fokus på servicedesign.......Rapporten omhandler internationaliseringen af designvirksomhede med special fokus på servicedesign....

  2. Adjuverende kemoterapi til patienter med rectumcancer--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Qvortrup, Camilla; Mortensen, John Pløen; Pfeiffer, Per

    2013-01-01

    A new Cochrane meta-analysis evaluated adjuvant chemotherapy (5-fluorouracil (5FU)-based, not modern combination chemotherapy) in almost 10,000 patients with rectal cancer and showed a 17% reduction in mortality corresponding well to the efficacy observed in recent studies, which reported...... a reduction in mortality just about 20%. The authors recommend adjuvant chemotherapy which is in accordance with the Danish national guidelines where 5-FU-based chemotherapy is recommended for stage III and high-risk stage II rectal cancer....

  3. God behandlingseffekt af botulinum toxin A hos systemisk sklerodermi patienter med digitale sår

    DEFF Research Database (Denmark)

    Nielsen, Jane Baumgartner; Hvid, Lone; Olesen, Anne Braae

    2014-01-01

    In this case we describe a successful combined treatment with local anaesthetics and botulinum toxin A. A 61-year-old man with systemic sclerosis of limited type presented treatment refractory digital ulcers on his toes with a poor response to conventional treatment. A combined treatment as above......-mentioned prevented a threatening amputation and improved quality of life, reduction of pain and healing of wounds. Using botulinum toxin A combined with local anaesthetics to severe toe digital ulcers in patients with systemic sclerosis may be a solution, when other treatments have been ineffective and amputation...

  4. Telemedicinsk praehospital diagnostik og visitation af en patient med akut lungeemboli

    DEFF Research Database (Denmark)

    Terkelsen, Astrid J.; Nielsen-Kudsk, Jens Erik; Andersen, Henning Rud

    2008-01-01

    pulmonary embolism. The ambulance was referred directly to the nearest department of cardiology where acute CT and echocardiography confirmed the diagnosis. Acute trombolysis was successful. Telemedicine may be beneficial in other medical emergencies than acute myocardial infarction. Udgivelsesdato: 2008......Mortality in untreated pulmonary embolism is high and short-term outcome depends on a timely diagnosis. In this case telemedicine involving 12-lead ECG and GSM-based communication between the patient in the ambulance and the telemedical staff resulted in remote pre-hospital suspicion of acute...

  5. Midler til lindring af mundtørhed og stimulation af spytsekretion

    DEFF Research Database (Denmark)

    Dynesen, Anja Weirsøe; Pedersen, Anne Marie Lynge; Jensen, Allan Bardow;

    2013-01-01

    effekt. I relation til risikoen for at udvikle caries, der er forhøjet hos den mundtørre patient, er det dog væsentligt at anbefale produkter uden sukker. Ligesom produktets indhold af syre og dermed det erosive potentiale er af betydning i forhold til udviklingen af dentale erosioner. Systemisk...

  6. Monitorering og komplikationer ved konservativ behandling af svær, akut pankreatitis

    DEFF Research Database (Denmark)

    Novovic, Srdan; Malmstrøm, Marie Louise; Andersen, Anders Møller

    2013-01-01

    Severe acute pancreatitis (SAP) is associated with a high morbidity and a mortality risk of up to 20%. Although much progress has occurred during the latest couple of years, there are still some major controversies on important issues such as monitoring, fluid therapy, antibiotic treatment...

  7. Behandling og håndtering af kongenitte melanocytære naevi

    DEFF Research Database (Denmark)

    Bahn, Kamille-Amalie; Hædersdal, Merete; Schmidt, Grethe

    2016-01-01

    Congenital melanocytic naevi (CMN) appear in approximately 2.6% of Caucasians. There is a major demand for treatment but no vital indication. Laser therapy, curettage and excision are available treatment modalities, but there is no ideal treatment with documented long-term effect and without side...

  8. Behandling med valproat under graviditet: beskrivelse af fire cases med føtalt valproatsyndrom

    DEFF Research Database (Denmark)

    Sabers, Anne; Larsen, Katja; Blichfeldt, Susanne;

    2009-01-01

    INTRODUCTION: Treatment with valproate is associated with an increased risk of teratogenicity compared to other antiepileptic drugs and can cause a complex of serious symptoms usually referred to as "foetal valproate symdrome" which is characterised by major and minor malformations in association...

  9. Acquisition and management of energy data. Opsamling og behandling af energi-data

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, K.E.

    1989-07-15

    Three computer programmes have been developed for the collection and management of measurement data in connection with a small dual-purpose power plant in a rural area. One of these is a modem program which enables readings of operational measurements to be taken and transferred over a geographical distance. Another program generates a daily report on the system's operation in a way which is determined by the user. An independent copying program is an extension of the graphic program which makes it possible to copy parts of data files over shorter periods of time and through individual data channels. Measuring data can form the basis of a control system. These types of program are presented in detail. (AB).

  10. Overlevelse efter lynnedslag og behandling af tilstødende komplikationer

    DEFF Research Database (Denmark)

    Pedersen, Malene Lægdsgaard; Uslu, Bülent; Lind, Morten Nikolaj;

    2011-01-01

    Lightning strike is an unpredictable weather phenomenon which can cause a variety of injuries to the human body. We present a case report with a 24-year-old male football player, who survived prolonged cardiac arrest after a lighting strike and then presented with multiple organ dysfunction due...

  11. Behandling af kardiogent shock med perkutan mekanisk cirkulationsstøtte

    DEFF Research Database (Denmark)

    Junker, Anders; Kaltoft, Anne; Hassager, Christian

    2013-01-01

    Despite rapid revascularisation with circulatory support using inotropes and intra-aortic balloon counterpulsation, the mortality of cardiogenic shock complicating acute myocardial infarction still exceeds 50%. An alternative treatment strategy is restoration of cardiac output by using a ventricu......Despite rapid revascularisation with circulatory support using inotropes and intra-aortic balloon counterpulsation, the mortality of cardiogenic shock complicating acute myocardial infarction still exceeds 50%. An alternative treatment strategy is restoration of cardiac output by using...... a ventricular assist device which can be inserted in the acute setting using the Impella device, a catheter-based flow pump. DanShock is a Danish multicentre study that will assess whether circulatory support using the Impella device will improve the outcome of cardiogenic shock compared to conventional...

  12. Danske anbefalinger for behandling af ankyloserende spondylitis og spondylartritis udarbejdet i et internationalt projektsamarbejde

    DEFF Research Database (Denmark)

    Pedersen, Susanne Juhl; Madsen, Ole Rintek; Erlendsson, Jon

    2008-01-01

    INTRODUCTION: The multinational initiative "3e Initiative in Rheumatology - Multi-national Recommendations for the Management of Ankylosing Spondylitis 2006-7" served the primary purpose of providing specific recommendations for the management of ankylosing spondylitis and spondyloarthritis...

  13. Forebyggelse og behandling af fedme hos børn og unge

    DEFF Research Database (Denmark)

    Michaelsen, Kim Fleischer; Mølgaard, Christian; Richelsen, Bjørn

    2006-01-01

    In the last 10 years, there has been a marked increase in the prevalence of obesity in children beginning at 3-4 years of age. The only realistic solution to the problem is prevention. Although there is limited evidence for the effectiveness of preventive programmes, there is a consensus...... that multisectorial action is urgently needed. This should include intervention at the family, school, municipal, regional and national levels, including the commercial sector and food companies. Treating childhood obesity has not been very successful, but some comprehensive community-based treatment programmes have...

  14. Konsensus for behandling og kontrol af borderline-tumor i ovariet i Danmark

    DEFF Research Database (Denmark)

    Lundvall, L; Lund, B A; Hansen, M

    1990-01-01

    In order to obtain an impression of the consensus in Denmark of the treatment and control of border-line tumours of the ovary (BTO), a questionnaire was sent to all 43 departments of gynaecology/obstetrics and of surgery with gynaecology/obstetrics. Thirty-seven (86%) departments replied. The res...... for radiotherapy. Treatment and control of BTO in Denmark are in agreement with current international principles....

  15. Medicinsk behandling af hypofosfatæmisk rakitis hos børn

    DEFF Research Database (Denmark)

    Rahbek, Elise Torp; Nielsen, Line Hougaard; Beck-Nielsen, Signe Sparre;

    2014-01-01

    regimen often fails to prevent bone deformity and reduced final height. The rarity and complexity of these diseases call for centralised specialist care and international collaboration. Future medical treatment may be improved by addition of new promising experimental treatments.......Hypophosphataemic rickets is a rare, genetic disorder resulting in defect bone mineralisation and rickets. The current medical treatment consists of phosphate supplementation and alfacalcidol, but side effects such as secondary hyperparat-hyroidism and nephrocalcinosis are common. This treatment...

  16. Tumornekrosefaktor alpha-haemning som led i behandling af uveitis hos børn

    DEFF Research Database (Denmark)

    Fledelius, Hans Callø; Nielsen, Susan M; Nissen, Kamilla Rothe

    2007-01-01

    To present our experience with anti-TNFalpha treatment of juvenile idiopatic arthritis (JIA) associated uveitis.......To present our experience with anti-TNFalpha treatment of juvenile idiopatic arthritis (JIA) associated uveitis....

  17. Behandling og diagnostik af tuberkulose: fremad med små skridt

    DEFF Research Database (Denmark)

    Bengård Andersen, Åse; Lillebæk, Troels; Bang, Didi;

    2011-01-01

    Development of new drugs for the treatment of drug sensitive and drug resistent tuberculosis is badly needed. Substantial progress has been made in the field and presently six new drug components are in clinical phase I and II trials. Drugs approved for other indications e.g. newer fluoroquinolones...

  18. Sekundær prævention af apopleksi med effektiv antihypertensiv behandling

    DEFF Research Database (Denmark)

    Knudsen, Signe Boye; Strandgaard, Svend; Paulson, Olaf B.

    2013-01-01

    In this meta-analysis, four of five placebo-controlled studies showed that antihypertensive treatment prevented stroke recurrence, most markedly in a study with a combination of an angiotensin-converting enzyme inhibitor and a diuretic. Studies with beta-blockers were not included. Two head...

  19. Fæcestransplantation som behandling af Clostridium difficile-infektion, colitis ulcerosa og metabolisk syndrom

    DEFF Research Database (Denmark)

    Carstensen, Jeppe West; Hansen, Axel Kornerup

    2014-01-01

    Faecal transplantation as a treatment for Clostridium difficile infection, ulcerative colitis and the metabolic syndrome Faecal transplantation as a therapeutic tool is increasingly reported in the scientific literature. Faecal transplantation is currently becoming a treatment for nosocomial......, refractory infections with C. difficile. Furthermore, faecal transplantation has been suggested as a treatment for ulcerative colitis as well as for the metabolic syndrome. In the accumulated literature faecal transplantations appear to be safe, effective and superior to current treatments. Faecal...

  20. Diagnose og behandling af osteoporose ved ikke-metastaserende cancer mammae

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Hansen, Mogens; Kristensen, Bent;

    2011-01-01

    The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer....

  1. Triage medfører hurtigere behandling af de mest syge

    DEFF Research Database (Denmark)

    Skriver, Claus; Lauritzen, Marlene Mauson Pankoke; Forberg, Jakob Lundager;

    2011-01-01

    Systematic process triage is a relatively unknown concept in Denmark. Currently there are no national recommendations regarding triage models for use in the emergency department (ED). Four medium-sized EDs from different regions across the country cooperated in a joint venture to develop a new...

  2. Vellykket behandling af supraventrikulær takykardi med modificeret Valsalvas manøvre

    DEFF Research Database (Denmark)

    Wallentin, Johan; Sjøl, Anette

    2016-01-01

    Supraventricular tachycardia (SVT) is a frequent challenge in medical emergency units. Adenosine, the drug of choice, may cause severe discomfort. The Danish Society of Cardiology's National Treatment Guidelines for SVT recommend first aid treatment with ''vagus stimulation such as carotid massage...

  3. Lægers tavshedspligt ved behandling af unge kan være et dilemma

    DEFF Research Database (Denmark)

    Boisen, Kirsten; Adolphsen, Caroline; Svensson, Jannet;

    2016-01-01

    to treatment. Young people value confidentiality, although they are unaware of the current guidelines. International guidelines on youth-friendly health services recommend split visits and confidential care while at the same time acknowledging parents' caretaking role, especially in adolescents with chronic...

  4. Danske anbefalinger for behandling af ankyloserende spondylitis og spondylartritis udarbejdet i et internationalt projektsamarbejde

    DEFF Research Database (Denmark)

    Pedersen, Susanne Juhl; Madsen, Ole Rintek; Erlendsson, J.

    2008-01-01

    INTRODUCTION: The multinational initiative "3e Initiative in Rheumatology - Multi-national Recommendations for the Management of Ankylosing Spondylitis 2006-7" served the primary purpose of providing specific recommendations for the management of ankylosing spondylitis and spondyloarthritis....... Systematic literature searches were performed in Medline by 3 international and a Danish bibliographic fellow. Outcome data were extracted and processed by use of routine methods from clinical epidemiology and statistics. The evidence was presented to the Danish rheumatologists. The participants were divided...... of these in the analysis. All 186 Danish rheumatologists were invited, and 26 (14,0%) participated in the meeting held in Copenhagen, December 2006. The individual recommendations were endorsed by 68-100% of the participants. CONCLUSION: Within the framework of the multinational 3e project, it was possible to develop...

  5. Laparoskopisk versus åben højresidig hemikolektomi til behandling af koloncancer

    DEFF Research Database (Denmark)

    Pommergaard, H C; Olsen, J.A.; Burgdorf, S.K.;

    2010-01-01

    , blood loss, surgical complications and mortality. RESULTS: The length of hospital stay was significantly shorter in the LRH group than in the ORH group (five vs. six, p = 0.023). Furthermore, the number of lymph nodes harvested was significantly larger in the LRH group than in the ORH group (23 vs. 15......, p complications including anastomotic leaks (eight vs. 14) and lower operation-related mortality (zero vs. three). None of these differences were statistically significant. CONCLUSION: LRH is comparable...... to ORH with regards to morbidity, mortality and blood loss. Furthermore, LRH is associated with a shorter hospital stay and a higher radical lymph node harvest than ORH. The results and the thesis that LRH will result in fewer hernias and better cosmetic outcomes makes LRH a promising surgical procedure...

  6. Begrænset evidens for bedste behandling af ukompliceret galdestenssygdom

    DEFF Research Database (Denmark)

    Rasmussen, Martin; Schulze, Svend; Bisgaard, Thue

    2016-01-01

    be cholecystectomy or watchful waiting is weak. This narrative-condensed review critically analyses current evidence with special focus on epidemiological risk factors of developing symptoms or complications related to gallbladder stones. The evidence for treatment is discussed.......Gallbladder stones will rarely lead to colic pain attacks and even more seldom to complications. A conservative watchful waiting strategy may be an alternative to cholecystectomy for uncomplicated symptomatic gallbladder stone disease. Evidence for whether the optimal treatment should...

  7. Glucagon-like peptide 1-baseret behandling af type 2-diabetes mellitus

    DEFF Research Database (Denmark)

    Knop, Filip Krag; Vilsbøll, Tina

    2007-01-01

    GLP-1 is secreted from the small intestine in response to ingestion of nutrients. It has a powerful insulinotropic effect and stimulates beta-cell growth and is therefore being developed for treatment of type 2 diabetes. The GLP-1 analogue, exenatide, is on the market in the USA as an add......-on therapy. Another strategy to increase circulating GLP-1 is to inhibit the enzyme DPP-IV which degrades endogenous GLP-1. GLP-1-based therapy results in HbA1c reductions of approximately 1 percent point, and the lack of serious side effects and the low risk of hypoglycaemic episodes are unique traits....

  8. Nonoperativ behandling af alvorlige stumpe pancreaslæsioner hos børn

    DEFF Research Database (Denmark)

    Penninga, Luit; Hillingsø, Jens

    2011-01-01

    Diagnosis and treatment of pancreatic trauma in children is challenging. Grade I and II lesions of the pancreas (Organ Injury Scale of the American Association of Trauma) are generally treated non-operatively. However, the optimal treatment of pancreatic lesions with involvement of the pancreatic...

  9. Udvikling og behandling af delirium hos kritisk syge børn

    DEFF Research Database (Denmark)

    Winther-Olesen, Marie; Afshari, Arash

    2012-01-01

    Delirium is a common and often under-recognised neuropsychiatric disorder in paediatric critical care, secondary to a general medical condition. Paediatric delirium (PD) is associated with high morbidity and mortality and prolonged stay at the intensive care unit. This review introduces the reader...

  10. Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

    OpenAIRE

    Pokorney, Sean D; Piccini, Jonathan P.; Stevens, Susanna R.; Patel, Manesh R.; Pieper, Karen S.; Halperin, Jonathan L.; Breithardt, Günter; Singer, Daniel E.; Hankey, Graeme J.; Hacke, Werner; Becker, Richard C.; Berkowitz, Scott D.; Nessel, Christopher C.; Mahaffey, Kenneth W.; Fox, Keith A A

    2016-01-01

    Background Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all‐cause mortality may guide interventions. Methods and Results In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose‐adjusted warfarin. Cox prop...

  11. Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

    OpenAIRE

    Pokorney, Sean D; Piccini, Jonathan P.; Stevens, Susanna R.; Patel, Manesh R.; Pieper, Karen S.; Halperin, Jonathan L.; Breithardt, Günter; Singer, Daniel E.; Hankey, Graeme J.; Hacke, Werner; Becker, Richard C.; Berkowitz, Scott D.; Nessel, Christopher C.; Mahaffey, Kenneth W.; Fox, Keith A A

    2016-01-01

    Background: Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all‐cause mortality may guide interventions. Methods and Results: In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose‐adjusted warfarin. Cox pr...

  12. Ischaemic cardiac outcomes in patients with atrial fibrillation treated with vitamin K antagonism or factor Xa inhibition: results from the ROCKET AF trial

    Science.gov (United States)

    Mahaffey, Kenneth W.; Stevens, Susanna R.; White, Harvey D.; Nessel, Christopher C.; Goodman, Shaun G.; Piccini, Jonathan P.; Patel, Manesh R.; Becker, Richard C.; Halperin, Jonathan L.; Hacke, Werner; Singer, Daniel E.; Hankey, Graeme J.; Califf, Robert M.; Fox, Keith A.A.; Breithardt, Günter

    2014-01-01

    Aims We investigated the prevalence of prior myocardial infarction (MI) and incidence of ischaemic cardiovascular (CV) events among atrial fibrillation (AF) patients. Methods and results In ROCKET AF, 14 264 patients with nonvalvular AF were randomized to rivaroxaban or warfarin. The key efficacy outcome for these analyses was CV death, MI, and unstable angina (UA). This pre-specified analysis was performed on patients while on treatment. Rates are per 100 patient-years. Overall, 2468 (17%) patients had prior MI at enrollment. Compared with patients without prior MI, these patients were more likely to be male (75 vs. 57%), on aspirin at baseline (47 vs. 34%), have prior congestive heart failure (78 vs. 59%), diabetes (47 vs. 39%), hypertension (94 vs. 90%), higher mean CHADS2 score (3.64 vs. 3.43), and fewer prior strokes or transient ischaemic attacks (46 vs. 54%). CV death, MI, or UA rates tended to be lower in patients assigned rivaroxaban compared with warfarin [2.70 vs. 3.15; hazard ratio (HR) 0.86, 95% confidence interval (CI) 0.73–1.00; P = 0.0509]. CV death, MI, or UA rates were higher in those with prior MI compared with no prior MI (6.68 vs. 2.19; HR 3.04, 95% CI 2.59–3.56) with consistent results for CV death, MI, or UA for rivaroxaban compared with warfarin in prior MI compared with no prior MI (P interaction = 0.10). Conclusion Prior MI was common and associated with substantial risk for subsequent cardiac events. Patients with prior MI assigned rivaroxaban compared with warfarin had a non-significant 14% reduction of ischaemic cardiac events. PMID:24132190

  13. Undervisning af tosprogede elever

    DEFF Research Database (Denmark)

    Horst, Christian

    2003-01-01

    Artiklen fremdrager hovedresultaterne fra Virginia P. Collier's og Wayne P. Thomas's længdeundersøgelser af tosprogede elever i USA, som formentlig er de mest omfattende undersøgelser af undervisningen af tosprogede elever overhovedet. Resultaterne diskuteres i relation til udviklingen af en...

  14. Lyden-af-Leg

    DEFF Research Database (Denmark)

    Toft, Herdis

    Præsentation af seniorforsker-projekt Lyden-af-Leg i et traderingsperspektiv og med indledende fokus på YouTube som traderings-platform.......Præsentation af seniorforsker-projekt Lyden-af-Leg i et traderingsperspektiv og med indledende fokus på YouTube som traderings-platform....

  15. Om distributionen af hvidhed

    DEFF Research Database (Denmark)

    Frello, Birgitta

    2007-01-01

    Med udgangspunkt i John Fords Western, Forfølgeren fra 1956, præsenteres en analyse af repræsentationer af race og overskridelse af raceskel, særligt i relation til konstitueringen af subjektpositioner, hvorfra spørgsmål om hvidhed og ikke-hvidhed kan afgøres....

  16. Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry

    Science.gov (United States)

    Haas, Sylvia; ten Cate, Hugo; Accetta, Gabriele; Angchaisuksiri, Pantep; Bassand, Jean-Pierre; Camm, A. John; Corbalan, Ramon; Darius, Harald; Fitzmaurice, David A.; Goldhaber, Samuel Z.; Goto, Shinya; Jacobson, Barry; Kayani, Gloria; Mantovani, Lorenzo G.; Misselwitz, Frank; Pieper, Karen; Schellong, Sebastian M.; Stepinska, Janina; Turpie, Alexander G. G.; van Eickels, Martin; Kakkar, Ajay K.

    2016-01-01

    Aims Vitamin K antagonists (VKAs) need to be individually dosed. International guidelines recommend a target range of international normalised ratio (INR) of 2.0–3.0 for stroke prevention in atrial fibrillation (AF). We analysed the time in this therapeutic range (TTR) of VKA-treated patients with newly diagnosed AF in the ongoing, global, observational registry GARFIELD-AF. Taking TTR as a measure of the quality of patient management, we analysed its relationship with 1-year outcomes, including stroke/systemic embolism (SE), major bleeding, and all-cause mortality. Methods and Results TTR was calculated for 9934 patients using 136,082 INR measurements during 1-year follow-up. The mean TTR was 55.0%; values were similar for different VKAs. 5851 (58.9%) patients had TTR<65%; 4083 (41.1%) TTR≥65%. The proportion of patients with TTR≥65% varied from 16.7% in Asia to 49.4% in Europe. There was a 2.6-fold increase in the risk of stroke/SE, 1.5-fold increase in the risk of major bleeding, and 2.4-fold increase in the risk of all-cause mortality with TTR<65% versus ≥65% after adjusting for potential confounders. The population attributable fraction, i.e. the proportion of events attributable to suboptimal anticoagulation among VKA users, was 47.7% for stroke/SE, 16.7% for major bleeding, and 45.4% for all-cause mortality. In patients with TTR<65%, the risk of first stroke/SE was highest in the first 4 months and decreased thereafter (test for trend, p = 0.021). In these patients, the risk of first major bleed declined during follow-up (p = 0.005), whereas in patients with TTR≥65%, the risk increased over time (p = 0.027). Conclusion A large proportion of patients with AF had poor VKA control and these patients had higher risks of stroke/SE, major bleeding, and all-cause mortality. Our data suggest that there is room for improvement of VKA control in routine clinical practice and that this could substantially reduce adverse outcomes. Trial Registration Clinical

  17. Identitetskonstruktioner af patienter

    DEFF Research Database (Denmark)

    Ottesen, Aase Marie; Strunck, Jeanne; Lassen, Inger Marie

    2015-01-01

    , however, that the implementation of New Public Management influences the welfare model in a neo-liberal direction. The study focuses on how such underlying ideologies may influence the dominant discourses present in the Health Act and how these discourses may construct different subject positions...

  18. Implementering af ny standard for kateterisering i forhold til ældre svagelige patienter > 65 år med hoftefraktur

    DEFF Research Database (Denmark)

    Bagger, Bettan; Varmarken, Tine; Pedersen, Niels

    2013-01-01

    klinisk standard. Metode: Der er udarbejdet et systematisk review med henblik på at identificere best evidence i forhold til brug af intermitterende versus permanent kateterisation. Der er implementeret en ny evidensbaseret standard i afdelingen, som evaluereres gennem en efterfølgende audit og...

  19. Lyden af musik - er lyden af idealisme

    DEFF Research Database (Denmark)

    Eigtved, Michael

    2015-01-01

    Programartiklen til Det Ny Teaters opsætning af Rodgers & Hammersteins The Sound of Music, undersøger musicalgenrens - og især de konkrete ophavsmænds- affinitet til fremstillingen af såvel idealistiske som ideologiske universer.......Programartiklen til Det Ny Teaters opsætning af Rodgers & Hammersteins The Sound of Music, undersøger musicalgenrens - og især de konkrete ophavsmænds- affinitet til fremstillingen af såvel idealistiske som ideologiske universer....

  20. Skal tavs iskaemi diagnosticeres og behandles?

    DEFF Research Database (Denmark)

    Bech, J; Egstrup, K; Mickley, H;

    1995-01-01

    Silent ischaemia (objective signs of myocardial ischaemia without symptoms) can be diagnosed using a conventional exercise-test or ambulatory Holter monitoring. Silent ischaemia is a frequent phenomenon in patients with ischaemic heart disease, i.e. patients with angina pectoris or previous...

  1. Autoimmun hepatitis. Fremtroedelsesformer, diagnostik og behandling

    DEFF Research Database (Denmark)

    Poulsen, L O; Tage-Jensen, U; Vyberg, M

    1992-01-01

    a few weeks to years. Seven patients had increased serum aspartate aminotransferase (ASAT) levels. The three patients with normal ASAT levels had hypoalbuminaemia, decreased level of prothrombin or high levels of serum immunoglobulin G. Moderate or high levels of smooth muscle antibody titer were...

  2. Behandling med kosmetiske bløddelsfyldere

    DEFF Research Database (Denmark)

    Thyssen, Jacob Pontoppidan; Christensen, Lise H; Zachariae, Claus O C

    2007-01-01

    An increasing number of patients undergo soft-tissue augmentation. The quality depends on the applied filler substance, the compliance of the patient and the physician. Long-term adverse reactions are referred to as nodules or granulomas. Nodules following degradable gels and polyacrylamide hydro...

  3. Diagnose, behandling og prognose ved fibromyalgi

    DEFF Research Database (Denmark)

    Danneskiold-Samsøe, Bente; Bartels, Else Marie; Amris, Kirstine

    2010-01-01

    It is important to recognize the diagnosis of fibromyalgia (FM) to adequately advise patients with this chronic pain disease. FM coexists with other rheumatic diseases and may therefore serve as a confounder in connection with estimation of disease activity. The aetiology and pathogenesis of FM...

  4. Vellykket konservativ behandling efter knivtraume mod hjertet

    DEFF Research Database (Denmark)

    Wærsted, Stian; Schou-Jensen, Katrine; Jensen, Tim;

    2012-01-01

    A five year-old girl was admitted to hospital following an accidental stab wound to the chest, inflicted by a knife placed in a dishwasher's cutlery tray. Investigations revealed a traumatic ventricular septum defect of the heart, with a pericardial effusion. Since the patient remained haemodynam...

  5. Skoling af lyst

    DEFF Research Database (Denmark)

    Bjerg, Helle

    2011-01-01

    På baggrund af interview med tre elevgenerationer fremanalyseres skolens virkningsfuldhed i skoling af lyst i et historisk perspektiv. I afhandlingen udvikles to teoretisk-analytiske optikker: Skolen som ideologisk rum - med inspiration fra Slavoj Zizeks ideologikritik, samt Skolen som affektivt...

  6. Bliv fan af AUB

    DEFF Research Database (Denmark)

    Hansen, Karsten Kryger

    2010-01-01

    Kort gennemgang af hvad det har betydet for Aalborg Universitetsbibliotek (AUB) at gå på Facebook.......Kort gennemgang af hvad det har betydet for Aalborg Universitetsbibliotek (AUB) at gå på Facebook....

  7. Sociale konsekvenser af byfornyelsen

    DEFF Research Database (Denmark)

    Andersen, Hans Skifter; Ærø, Thorkild

    byfornyede boliger. Kun meget få flytter dog som følge af byfornyelsen, men af andre grunde. I perioden efter byfornyelsen er der imidlertid en del beboere som vælger at flytte på grund af stigende huslejer. Byfornyelsen betyder, at beboersammensætningen ændres i retning af flere i beskæftigelse med høj...

  8. En verden af medier

    DEFF Research Database (Denmark)

    Tække, Jesper

    2009-01-01

    Bogen: 'En verden af medier – Medialiseringen af politik, sprog, religion og leg' anmeldes. Anmeldelsen kan læses på: http://ojs.statsbiblioteket.dk/index.php/mediekultur/article/view/1370/1499 Udgivelsesdato: 2009......Bogen: 'En verden af medier – Medialiseringen af politik, sprog, religion og leg' anmeldes. Anmeldelsen kan læses på: http://ojs.statsbiblioteket.dk/index.php/mediekultur/article/view/1370/1499 Udgivelsesdato: 2009...

  9. Den kardiovaskulaere risikoprofil og antihypertensiv behandling

    DEFF Research Database (Denmark)

    Zittel, S; Moll, C K E; Hamel, W

    2009-01-01

    Estimation of absolute cardiovascular risk is important for choice of primary as well as secondary cardiovascular prevention. In general, physicians are advised to use SCORE in apparently healthy subjects with optimal or normal blood pressure, the ESH risk stratification chart in patients...... with hypertension and either one or even better a combination of the two instruments in apparently healthy subjects with a high normal blood pressure. Udgivelsesdato: 2009-Jun...

  10. Nyrefunktionen under behandling med angiotensinkonverterende enzymhaemmere

    DEFF Research Database (Denmark)

    Rasmussen, K; Heitmann, M; Nielsen, J I;

    1995-01-01

    The use of ACE-inhibitors has increased greatly during the last years. They were first used in treating hypertension, but nowadays cardiac diseases, mainly cardiac failure, are common indications. This means that the drugs are used in the treatment of more elderly patients who often have generali......The use of ACE-inhibitors has increased greatly during the last years. They were first used in treating hypertension, but nowadays cardiac diseases, mainly cardiac failure, are common indications. This means that the drugs are used in the treatment of more elderly patients who often have...... generalised atherosclerosis. This means that the patients must be controlled more often after initiation of treatment, especially concerning kidney function, since treatment with ACE-inhibitors can cause pronounced changes in renal haemodynamics and kidney function. This review focuses on the effects of ACE......-inhibitors on renal haemodynamics and kidney function, which may be positive, with preservation of kidney function in diabetic and other chronic nephropathy, or negative, for example in cases with atherosclerotic stenosis of large or small renal arteries. It is concluded, that in cases of diabetic nephropathy an ACE...

  11. Billeder af verdens svovl

    DEFF Research Database (Denmark)

    Samson, Kristine

    2014-01-01

    Film- og billedmediet har en særlig plads i skildringen af vores samfund og økonomi. Produktionen i de vestlige samfund består i dag primært af tegn, symboler, billeder og begær, mens de forgangne tiders maskinelle og, ikke mindst, manuelle bearbejdning af materialer – det vi stadigvæk umiddelbar...

  12. Ensretning af historieundervisningen

    DEFF Research Database (Denmark)

    Rønhede, Søren

    2008-01-01

    "Det er ikke kun i Putins Rusland, at statsmagten vil dirigere historieundervisningen." (Politiken havde fokuseret på "ensretning af historieundervisningen" i Rusland) "Kanonen fra 2006 er undfanget af Udvalget til Styrkelse af Historie i Folkeskolen. Dette udvalg havde regeringen nedsat; men...

  13. Forankring af skolemadsordninger

    DEFF Research Database (Denmark)

    Brinck, Nenna Maria; Kristensen, Niels Heine; Hansen, Mette Weinreich

    Denne rapport præsenterer resultaterne af de undersøgelser, der er gennemført i delprojekt 4 i EVIUS evalueringen. Fokus i dette delprojekt er forankringen af skolemadsordningerne. Af undersøgelsen fremgår det, at støtteordningen har virket bedst på skoler, hvor skolelederen har inddraget elever,...

  14. Digital formidling af kulturarv

    DEFF Research Database (Denmark)

    En af tidens store kulturelle dagsordner drejer sig om digital tilgængeliggørelse af kulturarv. Fortidens spor dukker op i nye former på nettet - næsten alle kulturinstitutioner arbejder med, og befolkningen har fået helt nye muligheder for at se med og deltage. Digital formidling af kulturarv...

  15. Udredning af xerostomi og hyposalivation

    DEFF Research Database (Denmark)

    Pedersen, Anne Marie Lynge; Dynesen, Anja Weirsøe; Jensen, Siri Beier

    2011-01-01

    Mundtørhed kræver grundig undersøgelse Xerostomi er ofte associeret til betydelig nedsat spytsekretion, men kan forekomme, uden at der objektivt kan påvises nedsat spytsekretion. Udredning af patienter, som klager over mundtørhed, bør således altid inkludere en omhyggelig anamnese, en detaljeret ...

  16. Der er begrænset effekt af interferonbeta til behandling af sekundær progressiv multipel sklerose--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Schreiber, Karen; Voldsgaard, Ana; Sørensen, Per Soelberg

    2013-01-01

    Interferon (IFN)-beta 1b is approved for the treatment of secondary progressive multiple sclerosis (SPMS) with relapses in the EU. This Cochrane review analysed all double- or single-blinded randomised placebo controlled studies that had evaluated the efficacy of IFN-beta versus placebo in SPMS...

  17. AFS Monitoring The CERN AFS Console

    CERN Document Server

    CERN. Geneva

    2008-01-01

    CERN's AFS installation serves between 1 and 2 billion accesses per day to its around 20'000 users. Keeping track of the system's overall status and trying to find problems before the users do is not a trivial task, esp. as the installation is growing in almost all aspects. This talk will present CERN's AFS Console, a Lemon- and web-based monitoring tool used by the AFS administrators at CERN to quickly identify problematic entities (servers, partitions, volumes etc.) and to assist them in solving the issues found.

  18. Prekarisering af arbejdsmarkedet

    OpenAIRE

    Sebelin, Randa; Søndergaard Krogh, Niels; Olesen Dørup, Marie; Nielsen, Emil; Westerbye, Nanna

    2005-01-01

    Rapporten redegør for konsekvenserne af fleksibiliseringen af arbejdslivet for den enkelte ansatte. Med et fokus på prekære/løse ansættelser gennemgås først sociologisk teori af bl.a. Ulrich Beck, Oskar Negt og Richard Sennett, som alle fremhæver de negative sider af en løs tilknytning til arbejdsmarkedet. Den danske arbejdsmarkedsmodel og flexicurity-modellen drages ind som baggrundsviden for en vigtig forståelse af den høje tillid til forhandlingsproces frem for lovgivning vi...

  19. Tovholder og forløbskoordinator

    DEFF Research Database (Denmark)

    Wulff, Christian; Vedsted, Peter

    2011-01-01

    KOL - sygdom, behandling og organisation giver en omfattende gennemgang af alle aspekter omkring KOL patienter fra tidlig opsporing og diagnose til forebyggelse, behandling og sundhedsvæsenets organisation. Vinklen er tværfaglig og alle kapitler er skrevet af specialister på deres felt. Bogen er ...

  20. Installation af opvaskemaskine

    DEFF Research Database (Denmark)

    Christiansen, J.; Skibstrup Eriksen, S.; Nielsen, F.

    Denne SBI-anvisning er et led i en serie om modernisering af installationerne i den ældre boligmasse. Den henvender sig til både beboere, husejere, VVS-installatører og andre interesserede. Anvisningen indeholder almene afsnit om valg og placering af opvaskemaskine, sagsforløb ved installation......, forhold til myndigheder, priser, finansieringsmuligheder m.m. Anvisningen indeholder endvidere tekniske afsnit om vandinstallation, afløb og elinstallation i forbindelse med installation af opvaskemaskine....

  1. Analytiske beregninger af induktionsvarme

    DEFF Research Database (Denmark)

    Henningsen, Poul

    Ved opvarmning af et emne ved hjælp af induktion, placeres emnet i en spole. Spolen påføres en vekselstrøm og der induceres en sekundær strøm langs emnets overflade. Dybden af det strømførende lag i emnet afhænger af den på spolens påtrykte strømfrekvens. Ved høje frekvenser løber strømmen i et t...

  2. Bestyrer af egen ro

    DEFF Research Database (Denmark)

    Søndergård, Birger; L. Friis, Klaus

    2000-01-01

    Evnen til at håndtere en indre uro synes at være blevet en væsentlig egenskab i forhold til udviklingen af vort samfund og de hastige brud i kontinuiteten af et liv, der leves. arbejdsforhold. stress. arbejdsmiljø. arbejdsliv......Evnen til at håndtere en indre uro synes at være blevet en væsentlig egenskab i forhold til udviklingen af vort samfund og de hastige brud i kontinuiteten af et liv, der leves. arbejdsforhold. stress. arbejdsmiljø. arbejdsliv...

  3. Ledelse af Organisationens Kreativitet

    DEFF Research Database (Denmark)

    Hedemann, Lars

    2008-01-01

    forskel, så er man som leder nødt til at arbejde mere målrettet med de medarbejdere som forventes at præstere et kreativt udbytte. Inspireret af analyseværktøjet "KEYS, Assessing the Work Environment for Creativity" udviklet af den amerikanske psykolog og ledelsesforsker ved Harvard University, Teresa...... Amabile, blev en undersøgelse derfor gennemført i udviklingsafdelingerne, Idéland og Idélab hos Bang og Olufsen, for at få et indblik i anvendeligheden af KEYS som inspirationskilde for succesfuld ledelse af organisationens kreativitet....

  4. Konstruktion af transducer

    DEFF Research Database (Denmark)

    Henriksen, Lars; Nielsen, Martin Pram

    Formålet med dette midtvejsprojekt er at udarbejde en transducer til måling af pressers stivhed. Dette er gjort på baggrund af en gennemgang af både presse- og stativ-typer samtidig med at udbøjningssituationen beskrives. Der introduceres en ide, der udgør grundkonceptet for opmålingsproceduren o...... færdige transducer – Load cellen. Strain gauge sørger for dataopsamlingen fra load cellen. Disse kalibreres således at transduceren er klar til de videre målinger der ligger i forlængelse af dette projekt....

  5. The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) : Exploring the changes in anticoagulant practice in patients with non-valvular atrial fibrillation in the Netherlands.

    Science.gov (United States)

    Ten Cate, V; Ten Cate, H; Verheugt, F W A

    2016-10-01

    There are over 385,000 cases of atrial fibrillation (AF) in the Netherlands, with over 45,000 new cases each year. Among other things, AF patients are at high risk of stroke. Patients are often prescribed oral anticoagulation, such as vitamin K antagonists (VKA), to mitigate these risks. A recently introduced class of oral anticoagulants, non-vitamin K antagonists (NOAC), is quickly gaining currency in global clinical practice. This study provides insight into the changes these new drugs will bring about in Dutch clinical practice.GARFIELD-AF is a large-scale observational AF patient registry initiated in 2009 to track the evolution of global anticoagulation practice, and to study the impact of NOAC therapy in AF in particular. The registry includes a wide array of baseline characteristics and has a particular focus on: (1) bleeding and thromboembolic events; (2) international normalised ratio fluctuations; and (3) therapy compliance and persistence patterns. The results in this paper provide the baseline characteristics of the first cohorts of Dutch participants in this registry and discuss some of the consequences of the changes in anticoagulation practice.Although VKA therapy remains overwhelmingly favoured by Dutch practitioners, NOACs are clearly gaining in popularity. Between 2011 and 2014, NOACs constituted an increasingly large proportion of prescriptions for oral anticoagulants.The insights provided by the GARFIELD-AF registry can be used by healthcare systems to inform better budgetary strategies, by practitioners to better tailor treatment pathways to patients, and finally to promote awareness of the various available treatment options and their associated risks and benefits for patients.

  6. Compreensão de fala em situação de mensagem competitiva em afásicos Comprehension of competitive messages in aphasic patients

    Directory of Open Access Journals (Sweden)

    Karin Zazo Ortiz

    2008-01-01

    Full Text Available OBJETIVO: verificar o desempenho de pacientes afásicos com distúrbios leves de compreensão em tarefas de figura-fundo e atenção seletiva para sons verbais em escuta de mensagem competitiva. MÉTODOS: foram incluídos neste estudo pacientes afásicos com distúrbio de compreensão leve, identificados através da aplicação do teste M1-Alpha. Além disso, deveriam apresentar audiometria tonal nas freqüências de 500Hz, 1KHZ, 2KHZ, compatível com a realização de testes auditivos centrais, medidas de imitância acústica normais e reflexos contralateral presentes bilateralmente. Foi utilizado o teste de identificação de sentenças PSI (Pediatric Speech Inteligibility - versão em português. Inicialmente, todos os pacientes identificaram as frases que compõem o PSI à viva voz. Em seguida, foram submetidos ao Teste de Escuta Monótica e Dicótica. RESULTADOS: os pacientes apresentaram dificuldades de compreensão estatisticamente significantes na situação de mensagem competitiva ipsilateral, nas situações 0dB e -10dB, além de dificuldades de compreensão também na situação de mensagem competitiva contralateral MCC (- 40 dB. CONCLUSÕES: os pacientes afásicos apresentaram dificuldade na compreensão de estímulos verbais em tarefas de figura-fundo e atenção seletiva, perdendo parte da informação nestas condições. Os achados dessa pesquisa puderam contribuir de forma a elucidar em como a lesão cerebral e, conseqüentemente, o prejuízo de habilidades perceptuais auditivas pode interferir na compreensão de pacientes afásicos no dia-a-dia, em que várias mensagens concorrem de forma competitiva.PURPOSE: to analyze the performance of aphasic patients with mild comprehension disorders in tasks of back-image and selective attention to verbal sounds in listening tasks with competitive message. METHODS: the patients were submitted to an audiological assessment; acoustic immitance measures and measurements of acoustic reflex. An

  7. Antitrombotisk behandling ved iskæmisk apopleksi og transitorisk cerebral iskæmi

    DEFF Research Database (Denmark)

    Overgaard, Karsten; Poulsen, Tina Svenstrup; Husted, Steen

    2007-01-01

    Nærværende statusartikel omhandler antitrombotisk behandling ved transitorisk cerebral iskæmi (TCI) og iskæmisk apopleksi, dog omtales trombolyse ikke. Behandlingen bør individualiseres efter evidensbaserede principper som anbefalet i nationale og internationale kliniske retningslinjer. Ofte er der...

  8. Myopati hos en patient i behandling med simvastatin og fluconazol

    DEFF Research Database (Denmark)

    Pedersen, Jens Kristian; Lydolph, Magnus Christian; Somnier, Finn

    2016-01-01

    A 69-year-old female was admitted due to progressive loss of muscle strength following addition of fluconazole to long-term simvastatin treatment. Rhabdomyolysis was suspected and both drugs were discontinued. Forced diuresis was initiated together with a short course of prednisolone. After 21...

  9. Midtvejsevaluering af EGA handlingsplanen

    DEFF Research Database (Denmark)

    Møller, Niels; Hasle, Peter; Christiansen, Jørgen Møller

    Center for Alternativ Samfundsanalyse (CASA) og Institut for Teknologi og Samfund ved Danmarks Tekniske Universitet har gennemført denne midtvejsevaluering af arbejdsmarkedets parters handlingsplan mod reduktion af ensidigt gentaget arbejde. Undersøgelsen viser, at der er sket en betydelig...

  10. Kvalitetsvurdering af sundhedsoplysende materiale

    DEFF Research Database (Denmark)

    Osler, Merete; Bech, Lars; Sybille, Bojlén;

    1990-01-01

    Lægeforeningens Hygiejnekomités arbejdsgruppe vedrørende sundhedsoplysning har udarbejdet en "huskeliste" til brug for en kvalitetsvurdering af skriftligt sundhedsoplysende materiale......Lægeforeningens Hygiejnekomités arbejdsgruppe vedrørende sundhedsoplysning har udarbejdet en "huskeliste" til brug for en kvalitetsvurdering af skriftligt sundhedsoplysende materiale...

  11. Coaching af dit studieliv

    DEFF Research Database (Denmark)

    Hansen, Rasmus Thorning

    2008-01-01

    En generel beskrivelse af de problemer specialestuderende sidder med og hvorledes coaching kan hjælpe med at (gen)skabe motivation og fokus......En generel beskrivelse af de problemer specialestuderende sidder med og hvorledes coaching kan hjælpe med at (gen)skabe motivation og fokus...

  12. Hvordan integration af it?

    DEFF Research Database (Denmark)

    Toft, Herdis

    2008-01-01

    Bourdieu-perspektiv og en analyse af data fra museums- og skoleprojektet Din egen historie på nettet vises det, hvordan børnene opbygger en legehabitus, det vil sige aktivt tilegner sig og anvender færdigheder i brug af æstetiske teknikker, som er formler, de kan improvisere frit over. Kendskab til formler...

  13. Kvalitetssikring af pressvejseprocessen

    DEFF Research Database (Denmark)

    Rasmussen, Mogens H.

    Det oprindelige formål med dette arbejde var udvikling af procesovervågning til pressvejsning ved en udvalgt hovedgeometri. Hovedgeometrien, ring/rør geometrien i materialekombinationerne stålring til tinbronzerør, blev valgt efter en forundersøgelse. På baggrund af et litteraturstudie samt indle...

  14. Administration af informationsmodeller

    DEFF Research Database (Denmark)

    Hundebøl, Jesper

    2013-01-01

    En informationsmodel er i denne sammenhæng en digital repræsentation af et givent byggeri. Både offentlige og private bygherrer anvender informationsmodeller, når der 'bygges digitalt'. I denne artikel undersøges det, hvilke konkrete udfordringer der følger af digitaliseringen, hvor gennemgribend...

  15. Evaluering af VIFT

    DEFF Research Database (Denmark)

    Pedersen, Michael Svendsen

    Denne rapport indeholder en ekstern evaluering af aktiviteter i VIFT, Videncenter for bedre undervisning af tosprogede elever, der er etableret som et samarbejde mellem Videncenter for tosprogethed & interkulturalitet (UC2) ved Professionshøjskolen København (UCC), tidligere CVU København & Nords...

  16. Raman af hvide pigmenter

    DEFF Research Database (Denmark)

    Reeler, Nini Elisabeth Abildgaard; Nielsen, Ole Faurskov; Sauer, Stephan P. A.;

    2013-01-01

    Et samspil mellem kunst og kemi. I et samarbejde mellem Statens Museum for Kunst og Kemisk Institut på KU er Ramanspek-troskopi brugt til at definere sammensætningen af blandinger af blyhvidt og calcit i maleriers hvide pigmenter....

  17. Kuratering af Samtidskunst

    DEFF Research Database (Denmark)

    Kuratering af Samtidskunst er den første bogudgivelse i Danmark, der fokuserer på kuratering som fag og praksis. Kuratering spiller en stadig større rolle i samtidskunsten. Bogen er en introduktion til skiftende forståelser af udstillings- og kuratorpraksisser og deres udfordringer, indkredset ge...

  18. Ud af guldrammerne

    DEFF Research Database (Denmark)

    Munch, Anders V.

    2006-01-01

    Diskussion af den internationale indflydelse på dansk symbolisme og skønvirke med udgangspunkt i Johan Rohdes rejsejournaler og Emil Hannovers anmeldelser af internationale udstillinger og udgivelser. Særligt fokus er Gesamtkunstwerk-tanken som baggrund for at koble kunst og kunsthåndværk....

  19. Anvendelse af genmodificerede planter

    DEFF Research Database (Denmark)

    Møller, F.

    I rapporten vurderes mulighederne for at gennemføre velfærdsøkonomiske analyser af anvendelsen af genmodificerede planter. Der gøres rede for kravene til konse-kvensbeskrivelsen og for mulighederne for at prissætte såvel de markedsrelaterede som de ikke-markedsrelaterede konsekvenser. Mulighederne...

  20. Dialektisk billede af Benjamin

    DEFF Research Database (Denmark)

    Bøggild, Jacob

    2004-01-01

    Anmeldelse af Lars Brückner: "Løse blade. Læseren, kritikeren og fortælleren Walter Benjamin"......Anmeldelse af Lars Brückner: "Løse blade. Læseren, kritikeren og fortælleren Walter Benjamin"...

  1. Indsattes organisering af selvforplejning

    DEFF Research Database (Denmark)

    Kjær Minke, Linda

    2012-01-01

    organiserer sig i madgrupper. Dette dels af økonomiske og praktiske hensyn, men madgrupperne fungerer også som mulighedsrum til fremvisning af forskellige former for kapital, positionering og magt. Madgrupperne har derfor både økonomiske og sociale formål og har betydning for indsattes strategier i...

  2. Rivaroxaban versus warfarin in Japanese patients with non-valvular atrial fibrillation in relation to hypertension: a subgroup analysis of the J-ROCKET AF trial.

    Science.gov (United States)

    Matsumoto, Masayasu; Hori, Masatsugu; Tanahashi, Norio; Momomura, Shin-Ichi; Uchiyama, Shinichiro; Goto, Shinya; Izumi, Tohru; Koretsune, Yukihiro; Kajikawa, Mariko; Kato, Masaharu; Ueda, Hitoshi; Iekushi, Kazuma; Yamanaka, Satoshi; Tajiri, Masahiro

    2014-05-01

    The majority of the patients enrolled in the rivaroxaban vs. warfarin in Japanese patients with atrial fibrillation (J-ROCKET AF) trial had hypertension. In this subgroup analysis, we investigated differences in the safety and efficacy of rivaroxaban and warfarin in subjects with and without hypertension. The baseline blood pressure (BP) measurements of patients with hypertension in the rivaroxaban and warfarin groups were 130/77 mm Hg and 131/77 mm Hg, respectively, whereas those of patients without hypertension were 123/74 mm Hg and 124/73 mm Hg, respectively. The incidence rates of the principal safety outcomes in the rivaroxaban and warfarin groups were 18.39% per year and 16.81% per year, respectively, among patients with baseline hypertension (hazard ratio (HR): 1.10; 95% confidence interval (CI): 0.84-1.45) and 16.71% per year and 15.00% per year, respectively, among patients without hypertension at baseline (HR: 1.14; 95% CI: 0.66-1.97), indicating no significant interaction (P=0.933). The incidence rates of the primary efficacy endpoints in the rivaroxaban group and the warfarin group were 0.54% per year and 2.24% per year, respectively, in patients without baseline hypertension (HR: 0.25; 95% CI: 0.03-2.25), and 1.45% per year and 2.71% per year, respectively, in patients with baseline hypertension (HR: 0.54; 95% CI: 0.25-1.16), indicating no significant interaction (P=0.509). In conclusion, the safety and efficacy profile of rivaroxaban was similar to that of warfarin, independent of baseline hypertensive status.

  3. Radiojodbehandling af recidiverende hypertyreose hos patienter som tidligere er behandlet for diffus toksisk struma med subtotal strumektomi

    DEFF Research Database (Denmark)

    Vestergaard, H; Laurberg, P

    1993-01-01

    Radioiodine therapy is often employed for treatment of patients with relapse of hyperthyroidism due to Graves' disease, after previous thyroid surgery. Little is known about the outcome of this treatment compared to patients with no previous surgery. A total of 20 patients, who had received...... surgical treatment for Graves' hyperthyroidism 1-46 years previously and with relapse of hyperthyroidism, and 25 patients with hyperthyroidism due to Graves' disease and no previous thyroid surgery were treated with radioiodine, following the same protocol. Early after treatment the previously operated...... patients showed a higher sensitivity to radioiodine, with more cases of early hypothyroidism than non-operated patients. However, after 50 months of follow-up the outcome was identical. The results indicate that frequent assessment is necessary after radioiodine treatment of patients with previous thyroid...

  4. Smagen af svovl

    DEFF Research Database (Denmark)

    Madsen, P. V.; Sørensen, B. T.

    2007-01-01

    Et af Sydafrikas største industriområder ligger i landets tredje største by, Durban. Industriområdet kaldes for "South Durban Industrial Basin" (SDIB), hvor der er cirka 120.000 beboere. Boligerne ligger side om side med en bred variation af tung industri. Området er et sørgeligt eksempel på den ...... tidligere Apartheid styret byplanlægning, hvor regeringen i 1940'erne valgte at placere industri i et område hovedsageligt beboet af farvede og sorte mennesker....

  5. Hukommelsesproblemer blandt ældre patienter i almen praksis: betydning af pårørendeoplysninger

    DEFF Research Database (Denmark)

    Waldorff, Frans Boch; Haugbølle, Nils Wolff; Møller, Hans Christian;

    2006-01-01

    practices in Copenhagen inner city. The patients who agreed to participate were asked to complete a questionnaire regarding memory, quality of life, etc. Their GP completed a questionnaire independently, and a MMSE was subsequently given to the patient. Where consent was obtained from a patient, a postal......-24 (OR 4.5) and a low quality of life (OR 3.1). Furthermore, if the patient was male, caregivers were more likely to report memory problems. CONCLUSION: Memory impairment is commonly observed by caregivers, but is rarely discussed with a GP. The results indicate that more focus on the possibility......INTRODUCTION: The aim was to describe and analyse signs that make caregivers suspect memory problems among elderly patients in general practice. METHODS: This prospective study was conducted in October and November 2002 among all patients aged 65 or older who consulted a GP in a total of 17...

  6. Termisk forgasning af biomasse

    DEFF Research Database (Denmark)

    Indlæggene i referatet er gengivet efter båndoptagelser. Der er dog foretaget nogle enklte omskrivninger af hensyn til læseligheden. Foredragsholdernes overheads er endvidere blevet lagt ind i referatet....

  7. Supervision af psykoterapi

    DEFF Research Database (Denmark)

    SUPERVISION AF PSYKOTERAPI indtager en central position i uddannelsen og udviklingen af psykoterapeuter. Trods flere lighedspunkter med psykoterapi, undervisning og konsultation er psykoterapisupervision et selvstændigt virksomhedsområde. Supervisor må foruden at være en trænet psykoterapeut kende...... supervisionens rammer og indplacering i forhold til organisation og samfund. En række kapitler drejer sig om supervisors opgaver, roller og kontrolfunktion, supervision set fra supervisandens perspektiv samt betragtninger over relationer og processer i supervision. Der drøftes fordele og ulemper ved de...... forskellige måder, hvorpå en sag kan fremlægges. Bogens første del afsluttes med refleksioner over de etiske aspekter ved psykoterapisupervision. Bogens anden del handler om de særlige forhold, der gør sig gældende ved supervision af en række specialiserede behandlingsformer eller af psykoterapi med bestemte...

  8. Test af Software

    DEFF Research Database (Denmark)

    Dette dokument udgør slutrapporten for netværkssamarbejdet ”Testnet”, som er udført i perioden 1.4.2006 til 31.12.2008. Netværket beskæftiger sig navnlig med emner inden for test af indlejret og teknisk software, men et antal eksempler på problemstillinger og løsninger forbundet med test af...... administrativ software indgår også. Rapporten er opdelt i følgende 3 dele: Overblik. Her giver vi et resumé af netværkets formål, aktiviteter og resultater. State of the art af software test ridses op. Vi omtaler, at CISS og netværket tager nye tiltag. Netværket. Formål, deltagere og behandlede emner på ti...... række danske software-, elektronik- og IT-virksomheder....

  9. Sikker brug af bedside_UL-vejledt pleuracentese og ascitesdrændge hos patienter med maligne sygdomme

    DEFF Research Database (Denmark)

    Damstrup, Camilla Vantore

    2014-01-01

    and investigated the patients' medical files with regard to complications. In 29 pleuracentesises and 43 laparocentesises only one pneumothorax was registered (3.4%). This is comparable to previous studies and may suggest that it is safe to perform these procedures bedside in cancer patients with no complications....

  10. UL-vejledt anlæggelse af fødeepidural hos patient med torakolumbal skoliose

    DEFF Research Database (Denmark)

    Piosik, Zofia Maria; Helbo-Hansen, Søren; Sprehn, Michael

    2015-01-01

    Providing epidural analgesia in patients with scoliosis may be challenging. We describe ultrasound-guided insertion of an epidural catheter for labour analgesia and a following caesarean section in a patient with a thoracolumbar scoliosis. A well-functioning epidural catheter was easily inserted...

  11. Af Upraktiske Grunde

    DEFF Research Database (Denmark)

    Vaaben, Nana Katrine

    2001-01-01

    Artiklen baseres på studier af danske musikfans og handler om de objekter, de indsamler i forbindelse med at være fans. Der er to hovedargumenter, der løber gennem hele analysen. For det første at det indsamling af objekter handler om, er begær efter at kategorisere, ordne og systematisere, såled...

  12. Forebyggelse af kriminalitet

    DEFF Research Database (Denmark)

    Christiansen, U.; Jantzen, E.B.; Kirkegaard, O.

    Forebyggelse af kriminalitet i boligområder har længe stået på dagsordenen i alle vestlige samfund. Dansk Ingeniørforening og Ingeniørsammenslutningen har udviklet normer for kriminalpræventiv planlægning i boligområder siden midten af 1980'erne. To bebyggelser i Københavnsegnen er blevet planlag...

  13. Vitalisering af rettetheder

    DEFF Research Database (Denmark)

    Kristensen, René

    2012-01-01

    Kapitlet handler om at anvende det selvpsykologiske teorigrundlag i samspil med de systemisk konstruktionistiske ideer i arbejdet med at udvikle organisationer og samtidig kvalificere anvendelsen af PUMA -pædagogisk udredning i inklusionssammenhænge.......Kapitlet handler om at anvende det selvpsykologiske teorigrundlag i samspil med de systemisk konstruktionistiske ideer i arbejdet med at udvikle organisationer og samtidig kvalificere anvendelsen af PUMA -pædagogisk udredning i inklusionssammenhænge....

  14. Bearbejdning af Luhmanns organisationsteori

    DEFF Research Database (Denmark)

    Mortensen, Nils

    Som titlen siger, er det en gennemgang/præsertation af Luhmanns organisationsteori. Der er lagt særlig vægt på emnerne beslutning, ledelse opg forandring......Som titlen siger, er det en gennemgang/præsertation af Luhmanns organisationsteori. Der er lagt særlig vægt på emnerne beslutning, ledelse opg forandring...

  15. Selvmonitorering af blodglukose og sygdomsforståelse hos patienter med insulinbehandlet diabetes. Sammenhaeng med metabolisk regulation

    DEFF Research Database (Denmark)

    Wengler, K; Matzen, L E; Sindrup, S;

    1989-01-01

    A questionnaire investigation was undertaken to register the extent to which 212 insulin-treated diabetic patients undertook home measurements of blood glucose and the consequences which they drew from these measurements. This was compared with the metabolic regulation estimated by HbA1c. The ave...

  16. Anvendeligheden af GIS

    DEFF Research Database (Denmark)

    Winstrup, Mie; Levin, Gregor

    2011-01-01

    Fragmentering af naturen er en trussel mod biodiversiteten, og etablering af økologiske forbindelser/korridorer mellem naturområderne er én måde hvorved nedgangen i biodiversitet kan stoppes. Med Næstved Kommune som case-område har jeg undersøgt, hvordan analyser i GIS kan bruges til at udvælge...... omdannet til reelle korridorer, hvor bredden afhænger af arealdækket som forbindelserne krydser. I implementerings øjemed er det anvendeligt at vide om nogle forbindelser er særlig vigtige for at skabe mere sammenhængende natur. GIS er anvendeligt hertil, idet GIS kan bruges til at bestemme den enkelte...

  17. Realisering af Vision 2020

    DEFF Research Database (Denmark)

    Bertelsen, Niels Haldor; Hansen, Ernst Jan de Place

    Repræsentanter for byggesektoren har på 11 dialogmøder drøftet Erhvervs- og Byggestyrelsens "Vision 2020 - Byggeri med mening". Drøftelserne førte til formulering af en lang række initiativforslag til realisering af visionen. Den mest centrale udfordring bliver at reducere fejl og mangler i...... byggeriet. Branchen lægger også vægt på, at styringen af Vision 2020s reaisering sker i byggesektoren. Initiativforslagene er i rapporten samlet under 3 hovedområder. Det første hovedområde lægger vægt på bygningerne, brugerbehov og det globale samfund. Det andet omhandler processen og leverancesystemet...

  18. Ledelse af sociale institutioner

    DEFF Research Database (Denmark)

    Kofod, Kasper

    Ledelse af sociale institutioner giver et overblik over den enorme forandring, der er sket indenfor det sociale område i de sidste 25-30 år. Moderniseringen af den offentlige sektor har været gennemgribende, og udviklingen på det sociale område er gået mod større instirutioner og mod, at stadig...... flere beslutninger træffes lokalt. det betyder også,a t der kommeret øget fokus på ledelse af de enkelte sociale institutioner. Forandringer i omverdenedn som globalisering, individualisering, mangel på arbejdskraft og ændringer i omgangsformer påvirker også ledelsesvilkårene i de sociale institutioner...

  19. Reformen af erhvervsuddannelserne

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    2016-01-01

    Artiklen anlægger et politisk-historisk perspektiv på reformen af erhvervsuddannelserne (EUD) i 2014. Reformen markerede på nogle områder et markant brud med den hidtidige politik. Det gælder for ek-sempel indførelsen af adgangskrav og satsningen på talent og elite, som afløser de krav om social ...... ’blinde plet-ter’ og om den ureflekterede resultatstyring, som fortsætter med den aktuelle reform....

  20. Konstruktion af sandheden

    DEFF Research Database (Denmark)

    Nørreklit, Lennart

    2009-01-01

    Artiklen fremstiller sandhedsbegrebet som et læringsideal, som erstatter absolutisme og relativisme med læring. Indledningen bestemmer en problemorienteret ramme, som teorien indgår i: Mennesket er aktør, der danner virkelighed i form af relationer til sin omverden. Sandhedsbegrebet er forudsætni...... for en løbende sandhedsbestemmende læringsproces. Artiklen slutter med en diskussion af performative problemer, hvorigennem udsagn kan påvirke deres egen sandhedsværdi....

  1. Reduktion af stress og sygefravær blandt patienter med arbejdsrelaterede belastnings- og tilpasningsreaktioner henvist til Arbejdsmedicinsk klinik

    DEFF Research Database (Denmark)

    Glasscock, David John; Carstensen, Ole; Dalgaard, Vita Ligaya Ponce

    The literature contains many empirical studies of interventions aimed at reducing work-related stress. These include randomized controlled trials (RCT). In general it has been found that cognitive behavioural interventions are more effective than other forms of intervention. However, the research...... inclusion, patients were randomly assigned to either an intervention group or a control group. Participants in the control group were subsequently only followed via questionnaires. The intervention contains both individual cognitive behavioural therapy, conducted by a psychologist, and the offer...... functioning. Four months after baseline we found a significant treatment effect on two measures, - 3 - perceived stress and mental health. The intervention group experienced less stress and fewer symptoms compared to the control group. There was also a non-significant trend in the same direction concerning...

  2. Opbygning af laboratoriefaciliteter til induktionsopvarmning

    DEFF Research Database (Denmark)

    Henningsen, Poul

    Denne rapport beskriver de faciliteter, der er opbygget til induktionsopvarmning i IPL’s svejselaboratorium. Beskrivelsen omfatter: • Indkøb og installation af frekvensgenerator • Fabrikation af spoler • Positionering og fastholdelse af emner og spole • Måling og registrering.......Denne rapport beskriver de faciliteter, der er opbygget til induktionsopvarmning i IPL’s svejselaboratorium. Beskrivelsen omfatter: • Indkøb og installation af frekvensgenerator • Fabrikation af spoler • Positionering og fastholdelse af emner og spole • Måling og registrering....

  3. Monitorering af fysisk aktivitetsniveau (MOAN) hos indlagte patienter på geriatrisk afdeling - forsøgsprotokol

    DEFF Research Database (Denmark)

    Villumsen, Morten; Jørgensen, Martin Grønbech; Andreasen, Jane;

    (4):451-8. (2) Potter R, Ellard D, Rees K, Thorogood M. A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia. Int J Geriatr Psychiatry 2011 Oct;26(10):1000-11. (3) Årsrapport 2010 - DEN LANDSDÆKKENDE KVALITETSDATABASE...... and Go (TUG), rejse-sætte sig testen og Barthel score registreres for alle patienter ved indlæggelse og udskrivelse. Øvrige oplysninger vedrørende alder, køn, vægt, højde, demens, depression, årsag til indlæggelse, boligform, og pårørende indhentes fra journalen. Primær outcome for undersøgelsen er den...... som et kvalitetssikrringsprojekt. Reference List (1) Covinsky KE, Palmer RM, Fortinsky RH, Counsell SR, Stewart AL, Kresevic D, et al. Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with age. J Am Geriatr Soc 2003 Apr;51...

  4. Heterotop graviditet efter IVF-behandling med excision af rumperet interstitiel graviditet og senere kejsersnit nær termin

    DEFF Research Database (Denmark)

    Elers, Jimmi; Zingenberg, Helle; Bing, Mette H;

    2016-01-01

    We describe a rare case of heterotopic pregnancy following in vitro fertilization with transferring of two embryos in a 39-year-old woman with previous bilateral salpingectomy. An ultrasound examination was performed on the day before admission showing a vital intrauterine pregnancy and no ectopic...... pregnancy. The woman was admitted with a ruptured cornual pregnancy at ten weeks of gestation. Laparotomy was performed on vital indication with excision of the ruptured haemorrhagic cornual pregnancy. The intrauterine pregnancy continued uneventfully with obstetric and fetal medicine specialist monitoring...

  5. Indacaterol er en én gang dagligt inhaleret β 2-agonist til behandling af kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli

    2010-01-01

    The aim of pharmacological treatment of COPD is best possible disease control. Bronchodilators are accepted as the mainstay of COPD therapy. This short review focuses on the available data on indacaterol - a new once-daily beta2-agonist. The analysed studies show that indacaterol has clinically i...

  6. Udvikling af cerebrale infarkter hos en 17-årig mand i behandling med sertralin og lisdexamfetamin

    DEFF Research Database (Denmark)

    Martinussen, Malene; Debes, Nanette Mol; Christensen, Catrine;

    2016-01-01

    A 17-year-old male with ADHD who was treated with sertraline and lisdexamfetamine presented with transient episodes of speech impairment and right-sided hemiparesis preceded by headaches. Magnetic resonance imaging revealed three cerebral ischaemic lesions. Treatment was initiated with aspirin an...... be ruled out as risk factors.......A 17-year-old male with ADHD who was treated with sertraline and lisdexamfetamine presented with transient episodes of speech impairment and right-sided hemiparesis preceded by headaches. Magnetic resonance imaging revealed three cerebral ischaemic lesions. Treatment was initiated with aspirin...

  7. Nibe Bredning, klapning af oprensningsmaterialer og vurdering af sedimentspredning

    DEFF Research Database (Denmark)

    Larsen, Torben; Bentzen, Thomas Ruby

    Formålet med undersøgelsen er at beregne spredningen af klapmateriale oprenset fra sejlrenden til Nibe samt Draget. Klappladsen for begge lokaliteter er umiddelbart nordvest for Klitgaard Hage. Beregningen er foretaget vha. af numerisk modellering af strømforhold samt sedimenttransport. Til formå...

  8. Inklusion af utilpassede unge

    DEFF Research Database (Denmark)

    2015-01-01

    Anholt-projektet repræsenterer en alternativ pædagogisk interventionsform for utilpassede og sårbare unge. Projektet, der i en årrække har været afprøvet af ungdomsskoler og ungdomsorganisationer i Danmark, Tyskland, Østrig, Spanien, Portugal og Italien, bygger på tanker om erfaringsbaseret, ufor...

  9. Benchmark af erhvervsuddannelserne

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Wittrup, Jesper

    I dette arbejdspapir diskuterer vi, hvorledes de danske erhvervsskoler kan benchmarkes, og vi præsenterer resultaterne af en række beregningsmodeller. Det er begrebsmæssigt kompliceret at benchmarke erhvervsskolerne. Skolerne udbyder en lang række forskellige uddannelser. Det gør det vanskeligt...

  10. Benchmarking af kommunernes sagsbehandling

    DEFF Research Database (Denmark)

    Amilon, Anna

    Fra 2007 skal Ankestyrelsen gennemføre benchmarking af kommuernes sagsbehandlingskvalitet. Formålet med benchmarkingen er at udvikle praksisundersøgelsernes design med henblik på en bedre opfølgning og at forbedre kommunernes sagsbehandling. Dette arbejdspapir diskuterer metoder for benchmarking...

  11. Anmeldelse af: Gruppepsykologi

    DEFF Research Database (Denmark)

    Christensen, Bodil

    2009-01-01

    , kreativitet og nytænkning. Det er her, videnskabens virkelige fremskridt sker.” Sådan lyder et citat af Albert Einstein, som Lars Svedberg bruger for at sætte sin faglige fremstilling om gruppepsykologi i perspektiv. Gruppeorganisationen er nemlig ofte rum for/ eller kan være rum for denne synergieffekt, der...

  12. En skygge af modernitet

    DEFF Research Database (Denmark)

    2015-01-01

    Artiklen vil kort skitsere forskellige, samtidige konservative reaktioner på teknikken, hvis destruktive potentiale var blevet åbenbart i og med Første Verdenskrig, og derefter gennem en læsning af Drachmanns politiske og skønlitterære forfatterskab identificere nøgleelementer og begreber i Drach...

  13. Forplumring af historien

    DEFF Research Database (Denmark)

    Winther, Gorm

    2006-01-01

    Umiddelbart efer invasionen og samme år i 1956 fik Larsenfløjen udvirket en udtalelse fra DKPs forretningsudvalg, hvor det knæsattes at ethvert folk selvstændigt skulle kunne bestemme sin udviklingsvej, ligesom man fordømte påkaldelsen af hjælp fra broderpartierne udefra....

  14. Innovationen lider af teknologifetichisme

    DEFF Research Database (Denmark)

    Pedersen, Peder Holm

    2011-01-01

    Teknologisk innovation er udråbt som vejen til fremtiden for den danske velfærdsstat. Men vi risikerer at miste innovationens fulde potentiale, hvis vi tror, at innovation nødvendigvis skal lugte af teknologi. Nogle gange kan en sort affaldssæk også gøre det....

  15. Forankring af skolemadsordninger

    DEFF Research Database (Denmark)

    Brinck, Nenna Maria; Kristensen, Niels Heine; Hansen, Mette Weinreich

    I rapporten beskrives tre forældrebetalte skolemadsordninger, der blev etableret med støtte fra FødevareErhverv i 2008. Rapporten indeholder også resultater fra en spørgeskemaundersøgelse foretaget blandt elever og forældre i en 4. og 8. klasse på de tre caseskoler. Rapporten er en del af evaluer...

  16. Definition af et landdistrikt

    DEFF Research Database (Denmark)

    Søgaard, Villy

    2008-01-01

    Forskellige lande arbejder med meget forskellige definitioner af begrebet landdistrikt. Arbejdspapiret diskuterer først en række generelle krav til definitioner og anbefaler på den baggrund konkrete justeringer i forhold til den hidtidige danske praksis på området. Arbejdspapiret er blevet til i...

  17. Udlejers godkendelse af ny erhvervslejer

    DEFF Research Database (Denmark)

    Munk-Hansen, Carsten

    2009-01-01

    I artiklen er taget udgangspunkt i den »klassiske« afståelsessituation, hvor en lejer vil afhænde den i de lejede lokaler drevne virksomhed, og lejeren har afståelsesret til en af udlejer godkendt lejer, uden at kravene til den ny lejer er specificeret. På baggrund af Vestre Landsrets dom af 9/2 ...

  18. Monitering af korrosion i fjernvarmesystemer

    DEFF Research Database (Denmark)

    Hilbert, Lisbeth Rischel; Nielsen, Lars Vendelbo; Thorarinsdottir, R.I.

    2004-01-01

    Kontrol af korrosion i fjernvarmesystemer foregår primært ved kontrol af vandkvaliteten. Generel korrosion af kulstofstål undgås således normalt ved at holde iltkoncentration og ledningsevne lav og pH høj. Lokaliseret korrosion forekommer dog i systemerne og disse korrosionsangreb detekteres i fo...

  19. Anmeldelse af Evolution, Literature and Film

    DEFF Research Database (Denmark)

    Grodal, Torben Kragh

    2011-01-01

    Diskussion af basisproblemer i evolutionær fiktionsteori med udgangspunkt i en anmeldelse af Evolution, Literature and Film......Diskussion af basisproblemer i evolutionær fiktionsteori med udgangspunkt i en anmeldelse af Evolution, Literature and Film...

  20. Hætten af for Robin Hood

    DEFF Research Database (Denmark)

    Oxenbøll, Morten

    2010-01-01

    En historisk gennemgang af Robin Hood myten i anledning af den kommende Hood film med Russell Crowe i hovedrollen.......En historisk gennemgang af Robin Hood myten i anledning af den kommende Hood film med Russell Crowe i hovedrollen....

  1. En genlæsning af John Rawls i lyset af hans diskussion af forholdet til fremtidige generationer

    DEFF Research Database (Denmark)

    Lübcke, Poul

    2009-01-01

    På grundlag af en konsekventialistisk rekonstruktion af Rawls' politiske position gøres der rede for Rawls eksplicitte og implicitte vurdering af vores ansvar over for fremtidige generationer......På grundlag af en konsekventialistisk rekonstruktion af Rawls' politiske position gøres der rede for Rawls eksplicitte og implicitte vurdering af vores ansvar over for fremtidige generationer...

  2. Nye endokrine behandlinger forlænger overlevelsen ved kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Brasso, Klaus; Thomsen, Frederik Birkebæk; Berg, Kasper Drimer;

    2013-01-01

    Endokrin behandling af prostatacancer (PCa) har været anvendt i mere end 60 år og har stadig en væsentlig plads i behandlingen af patienter med avanceret PCa. Hos en voksen mand opretholder androgener celleantallet i prostata og undertrykker apoptose. Ophæves den androgene stimulation opnås en...... dobbeltvirkning: hæmning af DNA syntese og proliferation samt aktivering af apoptose. Kastrationsbehandling i form af orkiektomi eller behandling med LHRH agonister/antagonister er standard hos patienter med avanceret PCa, men effekten er tidsbegrænset og såkaldt kastrationsresistent progression af PCa optræder...

  3. Kontrol af patienter med levertraumer

    DEFF Research Database (Denmark)

    Osterballe, Lene; Helgstrand, Frederik; Hillingsø, Jens;

    2014-01-01

    Development of a hepatic pseudoaneurysm (HPA) is a well-known, yet rare complication after liver trauma. We found 135 cases reported in the literature since 1965. Ruptured HPAs may have severe consequences with sudden massive haemorrhage and death. A clear strategy towards diagnosis and management...... of HPA post liver trauma is needed and outlined in this paper. We recommend early detection and definitive treatment before enlargement and rupture....

  4. Patienters oplevelse af medicinsk brystkraeftbehandling

    DEFF Research Database (Denmark)

    Grønvold, Mogens; Jensen, Anders Bonde

    2007-01-01

    hair loss, nausea, hot flushes, mucositis, fatigue, and cognitive side effects. Overall quality of life, social relations, and sexuality may also be affected. Endocrine therapies are characterised by hot flushes, vaginal dryness, arthralgias, and reduced libido. Udgivelsesdato: 2007-Sep-10...

  5. Aflivning af heste

    DEFF Research Database (Denmark)

    Karlshøj, Merete; Fredsbo, Louise; Buhl, Rikke

    2007-01-01

    Det er efterhånden sjældent at heste dør af alderdøm. Ofte må ejer træffe den vanskelige beslutning om at lade hesten aflive. Da der tit er tale om en kær ven, er hesteejeren følelsesmæssigt påvirket. Det er derfor afgørende, at aflivningen foretages fagligt korrekt og professionelt.......Det er efterhånden sjældent at heste dør af alderdøm. Ofte må ejer træffe den vanskelige beslutning om at lade hesten aflive. Da der tit er tale om en kær ven, er hesteejeren følelsesmæssigt påvirket. Det er derfor afgørende, at aflivningen foretages fagligt korrekt og professionelt....

  6. Nedtrykt af negative nyheder

    DEFF Research Database (Denmark)

    Skovsgaard, Morten; Søberg, Pernille Frantz

    2016-01-01

    I adskillige år er det blevet debatteret, hvorvidt nyhedernes negative fokus har konsekvenser for borgerne, og om det i sid-ste ende får flere til at vende ryggen til nyhederne. Vores viden om effekterne af positive og negative nyheder er dog begrænset, og derfor undersøges det i denne artikel......, hvordan henholdsvis positive og negative tv-nyheder påvirker seernes humør, hukom-melse af information fra indslaget og lyst til at se yderligere tv-nyheder. Det gør vi i et survey-eksperiment (N=204), hvor tre grupper så enten et originalt indslag eller det samme indslag klippet med henholdsvis et...

  7. Relationel skabelse af ledelsesidentitet

    DEFF Research Database (Denmark)

    Hersted, Lone; Madsen, Charlotte Øland; Michelsen, Randi Riis

    2014-01-01

    forestillinger om, hvad det vil sige at være leder. Disse forestillinger er alle relationelt og kulturelt skabte og præger ofte ledere i deres daglige beslutningstagen og disponering i en sådan grad, at det får betydelige følgevirkninger for resten af organisationen og dens brugere/kunder og øvrige interessenter....

  8. Optisk kvantificering af gopler

    DEFF Research Database (Denmark)

    Christensen, Jens Tang

    efterfølgende med specielt udviklet software, med henblik på arts-, størrelses- og antalsfordeling. Indledende tests har vist, at mens Aurelia og Cyanea nemt registreres i lysgardinet, idet de lyser kraftigt op, er brydningsindekset for små individer af Mnemiopsis så tæt på vand, at der kræves stor kontrast på...

  9. Anvendelser af Pervasive Communication

    DEFF Research Database (Denmark)

    Brønsted, Jeppe

    I øjeblikket er den måde, vi kommunikerer på, ved at ændre sig drastisk. Fra at vi for få år siden var nødt til at nøjes med Internetkommunikation mellem stationære computere, forbindes en masse nye typer af enheder i dag på nye måder. Da vi nu ikke længere er bundet til en computer, der ikke kan...... flytte sig, bliver en masse nye ting mulige, fordi vi er forbundet med omverdenen i enhver kontekst. Da vi traditionelt ikke tænker i at være forbundet altid overalt er det ikke let at se, hvordan dette nye paradigme påvirker os i vores hverdag og hvordan vi kan udnytte det til nye forretnings- og...... forskningsmuligheder. For at gøre det hele lidt mere konkret, præsenteres i dette dokument en række eksempler på brug af Pervasive Communication. Udvalget af eksempler skal ikke ses som værende udtømmende, men snarere som håndplukkede eksempler der hver repræsenterer en genre. I dokumentet er både valgt...

  10. Innovation af innovation

    DEFF Research Database (Denmark)

    Harste, Gorm

    2009-01-01

    , at innovation af innovationen forsøges gennemført på en måde, hvor tiden kræves at forholde sig til sin egen tidslighed i form af fremtid, nutid, fortid og ikke mindst i form af samtidighed. I tiden skal vi iagttage, hvordan vi iagttager tiden. Vi dobbelt-koder tiden på samme måde, som forskning forsker i...... organisationssystemerne. De to typer systemer kan noget helt bestemt med fænomenet tid. De kan synkronisere. Analyseres organisationssystemer ser vi, imidlertid at innovation kræver ro. Stærkt innovative systemer er militærsystemet og kunstsystemet, der også inddrages, og hvor vi ser paradokset mellem innovation og...... involution. Tid er med et medium og ikke et lufttomt rum. Tid er end ikke en gasart, men udgør et solidt fluidum, som samfundet bader i og flyder i, konstant i bevægelse. Reformer forudsætter former, og innovation forudsætter involution. Kun sådan muliggøres evolution....

  11. Sammenhængende forløb for patienter med KOL, med særlig fokus på teknologi

    DEFF Research Database (Denmark)

    Vestergaard*, Kitt; Bagger, Bettan; Bech, Lone

    2014-01-01

    /e-health-implementation Case study: UK Department of Health: Whole System Demonstrator program http://www.kpmg.com/Global/en/IssuesAndInsights/ArticlesPublications/accelerating-innovation/Documents/ehealth-implementation.pdf 2. Danske Regioner, Kommunernes Landsforening, Ministeriet for Sundhed og Forebyggelse, Social- og...... Integrationsministeriet, Erhvervs- og Vækstministeriet, Økonomi- og Indenrigsministeriet & Finansministeriet (2012): National handlingsplan for udbredelse af telemedicin, Fonden for Velfærdsteknologi 3. Sundhedsstyrelsen (2007), Resume af anbefalinger for KOL. Tidlig opsporing, opfølgning, behandling og rehabilitering af...

  12. Prospective surveillance study of haemophilia A patients switching from moroctocog alfa or other factor VIII products to moroctocog alfa albumin-free cell culture (AF-CC) in usual care settings.

    Science.gov (United States)

    Parra Lopez, Rafael; Nemes, Laszlo; Jimenez-Yuste, Victor; Rusen, Luminita; Cid, Ana R; Charnigo, Robert J; Baumann, James A; Smith, Lynne; Korth-Bradley, Joan M; Rendo, Pablo

    2015-10-01

    This prospective, open-label, postauthorisation safety surveillance study assessed clinically significant inhibitor development in patients with severe haemophilia A transitioning from moroctocog alfa or other factor VIII (FVIII) replacement products to reformulated moroctocog alfa (AF-CC). Males aged ≥ 12 years with severe haemophilia A (FVIII:C) 150 exposure days (EDs) to recombinant or plasma-derived FVIII products, and no detectable inhibitor at screening were enrolled. Primary end point was the incidence of clinically significant FVIII inhibitor development. Secondary end points included annualised bleeding rate (ABR), less-than-expected therapeutic effect (LETE), and FVIII recovery. Patients were assigned to one of two cohorts based on whether they were transitioning to moroctocog alfa (AF-CC) from moroctocog alfa (cohort 1; n=146) or from another recombinant or plasma-derived FVIII product (cohort 2; n=62). Mean number of EDs on study was 94 (range, 1-139). Six positive FVIII inhibitor results, as determined by local laboratories, were reported in four patients; none were confirmed by a central laboratory, no inhibitor-related clinical manifestations were reported, and all anti-FVIII antibody assays were negative. Median ABRs were 23.4 and 3.4 in patients categorised at baseline as following on-demand and prophylactic regimens, respectively; 86.5% of bleeding episodes resolved after one infusion. LETE incidence was 0.06% and 0.19% in the on-demand and prophylaxis settings, respectively. FVIII recovery remained constant throughout the study. No new safety concerns were identified. This study found no increased risk of clinically significant FVIII inhibitor development in patients transitioning from moroctocog alfa or other FVIII replacement products to moroctocog alfa (AF-CC).

  13. EMDR-behandling  : Barns och ungdomars upplevelser en kvalitetssäkringsstudie 

    OpenAIRE

    Fredin, Ingela

    2005-01-01

    Föreliggande studie är dels ett led i att kvalitetssäkra EMDR (Eye Movement Desensitization and Reprocessing) som behandlingsmetod för barn och ungdomar och dels att utröna om behandlingen bidragit till ett förbättrat mående. EMDR som behandlingsmetod för barn och ungdomar har stöd i kontrollerade studier, men ytterligare forskning behövs. I den här studien deltog åtta barn och ungdomar med varierande diagnoser, vilka fått EMDR-behandling i barn- och ungdomspsykiatrisk öppenvård. Behandlingen...

  14. Lektier Online - didaktisk design af et uformelt online læringsrum?

    Directory of Open Access Journals (Sweden)

    Nina Bonderup Dohn

    2016-06-01

    Full Text Available I denne artikel undersøger vi det didaktiske design i Lektier Online; et online lektiehjælpstilbud for folkeskole- og gymnasieelever baseret på frivillige universitetsstuderende som lektiehjælpere. Vi identificerer fire betydninger af ’didaktisk design’, som alle behandles for Lektier Online. Vi opstiller en hypotese om Lektier Online-konceptet som frembydende et forholdsvis uformelt læringsrum samt tre eksplorative forskningsspørgsmål, der adresserer brugen af Lektier Online-platformens forskellige medier, deres virkemåde i læringskommunikationen mellem lektiehjælper og elev, samt muligheder for at kvalificere denne læringskommunikation didaktisk. Hypotese og forskningsspørgsmål undersøges gennem et eksplorativt observationsstudie, hvor lektiehjælpssessioner analyseres vha. positionerings- og affordanceteori. Vi konkluderer, at lektiehjælper og elev i samarbejde forhandler læringskommunikationen med anknytning til et lærer-elev narrativ og peger på, hvordan de primære kommunikationsmedier, tale og chat, samt de primære arbejdsmedier, digital tavle og Google Docs, bidrager i denne forhandling.

  15. Korrosionshastigheder af rene zinkcoatings

    DEFF Research Database (Denmark)

    Bech-Nielsen, G.; Tang, Peter Torben; Ulrich, Dan

    1991-01-01

    Det har længe været den fremherskende opfattelse i galvanobranchen, at et zinkbad var et zinkbad og at der, tiltrods for de forskellige leverandørers gyldne løfter, ikke var den store forskel på de bade der kan købes på markedet idag. Det har ydermere været den almindelige opfattelse, at zinkbade......-bestandighed og udseende. Badenes alder har også vist sig at have endog meget stor betydning for kvaliteten af belægningerne....

  16. Kulturelle spejlinger af Profeten Muhammed

    DEFF Research Database (Denmark)

    Høgsbro Lading, Åse

    2008-01-01

    Artiklen er en analyse af to forløb i den såkaldte Muhammedkrise, der udspringer af Jyllandspostens offentliggørelse af karrikaturer af profeten Muhammed. Den første i 2006 ses som et  udspil, der først og frememst er styret  af markedsmæssige interesser, og hvor de globale reaktioner kom bag på ...... forsvar opleves  af avisen i splitting-kategorier: enten kan man sige alt, eller også har man ikke ytringsfrihed. Artiklen slutter med et ønske om, at mere komplekse syn på de globale relationer kan etableres...

  17. Anvendelse af MIP ved kildekarakterisering og vurdering af nedbrydning af chlorerede opløsningsmidler

    DEFF Research Database (Denmark)

    Broholm, Mette Martina; Janniche, Gry Sander; Damgaard, Ida;

    2014-01-01

    Membrane Interface Probing (MIP) er et 'direct push' screeningsværktøj, som kan anvendes ved karakterisering af forurenede grunde. Karakterisering af kildeområder med chlorerede opløsningsmidler (som DNAPL) udgør et vigtigt led i udviklingen af den konceptuelle forståelse, som er essentiel...... for risikovurdering og valg af afværgestrategi. Integreret karakterisering med en række metoder for direkte såvel som indirekte dokumentation af DNAPL i moræneler, herunder MIP, er beskrevet i Kerrn-Jespersen et al. (2013). Det samlede DNAPL-karakteriseringsprojekt er beskrevet i detaljer i Janniche et al. (2013). En...... vurdering af anvendte detektorer for MIP er foretaget af Olsson (2013). Ved karakterisering af forurening med bl.a. chlorerede opløsningsmidler er der behov for en vurdering af forureningssammensætning og nedbrydning. Tilsvarende vurdering er nødvendig, når udviklingen af stimuleret reduktiv dechlorering...

  18. En verden drevet af vindkraft

    DEFF Research Database (Denmark)

    Aukdal, Kenneth Martin

    2000-01-01

    For over 100 år siden opstillede Poul la Cour og et hold videnskabsmænd den første testvindmølle i Danmark. Det var den spæde start til en udvikling, der har gjort Danmark til verdens førende eksportør af vindkraftteknologi. Over 60% af den elektricitet,der produceres af vindmøller i verden i dag...

  19. Slaver af Væksten

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen

    2004-01-01

    Artiklen rejser spørgsmålet om der, foruden den miljømæssige nødvendighed af at bremse væksten i Brutto National Produktet, også er direkte meneskelige fordele ved et sådant skridt. Dette aspekt er illustreret med de stigende negative følger af velstanden i USA og andre overflodslande, i form af ...

  20. Sammenligning af energiforbrug i supermarkeder

    DEFF Research Database (Denmark)

    Knudsen, Hans Jørgen Høgaard

    2005-01-01

    Formålet med det her omtalte projekt har været at sammenligne energiforbruget til køling i fire supermarkeder af sammenlignelig størrelse men med forskellig opbygning af køleanlægget. To af supermarkederne har nyudviklede kaskadeanlæg med CO2 i lavtemperaturkredsen og R404A i højtemperaturkredsen...

  1. Centralisering overfor decentralisering af varelagre

    DEFF Research Database (Denmark)

    Graungaard Pedersen, Søren; Zachariassen, Frederik

    2010-01-01

    store virksomheder. I Danmark går langt størstedelen af virksomheder under betegnelsen små og mellemstore virksomheder (SMV) og for en stor andel af disse, er udfordringen med effektiv styring af varelagre også relevant. Denne artikel beskæftiger sig med udfordringen mellem centralisering overfor...... decentralisering af varelagre i SMV. Det viser sig, at der er betydelige forskelle i, hvilke argumenter der er for og imod, når udfordringen ses fra et SMV-perspektiv....

  2. Coaching af sygedagpengemodtagere

    DEFF Research Database (Denmark)

    Coop Henriksen, Annemette

    SFI gennemførte i foråret 2008 til foråret 2009 en pilotundersøgelse om coaching. Undersøgelsen var designet som et lodtrækningsforsøg og omfattede 42 kvindelige sygedagpengemodtagere fra Rødovre Jobcenter, der var sygemeldt med psykiske lidelser i form af stress, depression eller udbrændthed eller...... med lidelser i bevægeapparatet. Undersøgelsen er bestilt og finansieret af Rødovre Jobcenter. I rapporten undersøges, om coaching kan bidrage til at bringe sygedagpengemodtagere i arbejde eller tættere på arbejdsmarkedet målt ved, om deltagerne får fx øget motivation, mere selvtillid, øget afklaring...... og færre symptomer på sygdom. Undersøgelsen viser, at gruppen, der har modtaget coaching, oplever en positiv udvikling i forhold til stress, depression og udbrændthed. Gruppen, der modtog coaching, har den tydeligste positive udvikling, men begge grupper har oplevet en helbredsmæssig fremgang i...

  3. Relevansen af Aristoteles' etik for konceptionen af eksistentiel terapi

    DEFF Research Database (Denmark)

    Dræby, Anders

    Siden sin undfangelse i begyndelsen af det 20. århundrede har den eksistentielle terapi repræsenteret et filosofisk funderet alternativ til de former for terapeutisk praksis, der er funderet i den funktionalistiske medicinske metafysik. Anvendelse af elementer fra Aristoteles' etik muliggør en...

  4. En systemteoretisk analyse af underviseres medlemskab af uddannelsessteder

    DEFF Research Database (Denmark)

    Kaspersen, Steffen Warming

    2014-01-01

    Afhandlingen undersøger ved hjælp af Niklas Luhmanns systemteori, hvordan undervisere på to uddannelsessteder der skal fusionere, er med til at bidrage til det nye uddannelsesstedets selvbeskrivelse. Der konkluderes, at undervisernes egen iagttagelse af uddannelsesstedet afgør hvilke faktorer der...

  5. Politisk brug af historien og legitimering af nutiden i Jugoslavien

    DEFF Research Database (Denmark)

    Humlebæk, Carsten

    2014-01-01

    Anmeldelse af: Tea Sindbæk: Usable History? Representations of Yugoslavia’s difϔicult past from 1945 to 2002, Aarhus University Press 2013.......Anmeldelse af: Tea Sindbæk: Usable History? Representations of Yugoslavia’s difϔicult past from 1945 to 2002, Aarhus University Press 2013....

  6. Skal vi synge den originale eller folkelige version af vores danske sange?

    DEFF Research Database (Denmark)

    Olsen, Jens Stig

    2015-01-01

    Artiklen behandler problemet med, at sange har en tendens til at ændre sig over tid og flittig brug, og via nogle kendte eksempler behandler den spørgsmålet om, hvordan vi kan forholde os til denne problematik.......Artiklen behandler problemet med, at sange har en tendens til at ændre sig over tid og flittig brug, og via nogle kendte eksempler behandler den spørgsmålet om, hvordan vi kan forholde os til denne problematik....

  7. Simulering af dagslys i digitale modeller

    DEFF Research Database (Denmark)

    Villaume, René Domine; Ørstrup, Finn Rude

    2004-01-01

    Projektet undersøger via forskellige simuleringer af dagslys, kvaliteten af visualiseringer af komplekse lysforhold i digitale modeller i forbindelse med formidling af arkitektur via nettet. I en digital 3D model af Utzon Associates Paustians hus, simulers naturligt dagslysindfald med  forskellig...... Renderingsmetoder som: "shaded render" /  ”raytraceing” /  "Final Gather /  ”Global Illumination”...

  8. The Role of U2AF1 Mutations in the Pathogenesis of Myelodysplastic Syndromes

    Science.gov (United States)

    2014-10-01

    effect has been previously reported in acute myeloid leukemia (AML) patient samples with U2AF1 mutations . To prioritize altered junctions for...hematopoiesis and pre-mRNA splicing observed in patients with U2AF1 mutations . This study also identifies changes in gene isoform expression unique to U2AF1...making it one of the most commonly mutated genes in MDS. Overall, mutations in spliceosome genes occur in up to 57% of patients with MDS, further

  9. Anbefalinger til organisering af uddannelserne

    DEFF Research Database (Denmark)

    Andersen, Lars; Andersen, Lars Døvling; Hornemann, Birte C.;

    2009-01-01

    Notatet sammenfatter de diskussioner, som det af fakulteterne nedsatte udvalg vedrørende nye undervisnings- og eksamensformer har haft, og de anbefalinger til en omlægning af vores uddannelsessystem, som udvalget har valgt at give. Notatet er samtidig en begyndelse på en erfaringsudveksling om ny...

  10. Kvalifikation af den optiske aftastning

    DEFF Research Database (Denmark)

    Sobiecki, René

    Hvor koordinatmålemaskinen i årtier har indtaget en nøgleposition i en virksomhed til fremskaffelse af måledata, ser vi nu en udvikling i retning af mere og mere optisk måleudstyr. Profilprojektoren er vendt tilbage i en ny avanceret form. Fordele og ulemper ved mekanisk kontra optisk måling er v...

  11. Virkelighedsflugt og masser af sex

    DEFF Research Database (Denmark)

    Lorentzen, Rasmus Fink

    2011-01-01

    I artiklen laves en læsning af ungdomsromanen "6" (2010) af Ronni Andersen. Dernæst udfoldes en række litteraturpædagogiske forslag tilen undervisning i romanen i skolens ældste klasser. Arbejdsforslagene er baseret på en kompetencetilgang til danskfaget og rummer fire værksteder hvor eleverne sk...

  12. Midtvejsevaluering af Pulje til Landsbyfornyelse

    DEFF Research Database (Denmark)

    Jensen, Jesper Ole; Blach, Vigdis E. Magnusdatter

    og bidrage til en helhedsorienteret og fremadrettet indsats i en række kommuner i de danske yderområder. Midtvejsevalueringen belyser effekten af puljen og kommunernes erfaringer med administrationen af puljen. Evalueringen er gennemført som en internet-baseret spørgeskemaundersøgelse (survey) blandt...

  13. Evaluering af den fleksible barselsorlov

    DEFF Research Database (Denmark)

    Marianne Olsen, Bente

    forældreorloven. Undersøgelsen viser også, at der er en række områder, hvor kommunerne mener, at orlovsreglerne udgør en administrativ byrde. Det bliver ekstra tungt, fordi det IT-system, der understøtter administrationen af barselsreglerne, ikke fungerer optimalt. Omring to tredjedel af de adspurgte...

  14. Evalueringen af den fleksible barselorlov

    DEFF Research Database (Denmark)

    Marianne Olsen, Bente

    forældreorloven. Undersøgelsen viser også, at der er en række områder, hvor kommunerne mener, at orlovsreglerne udgør en administrativ byrde. Det bliver ekstra tungt, fordi det IT-system, der understøtter administrationen af barselsreglerne, ikke fungerer optimalt. Omring to tredjedel af de adspurgte...

  15. Dental Assistant Specialty, AFS 981X0.

    Science.gov (United States)

    1982-12-01

    Preventive Dentistry) career ladder emerged as a lateral specialty in 1965. In 1972, the 983X0 AFS (Dental Assistant), another lateral career field...GRP588, N=37) E. Prosthodontic Assistants (GRP453, N=35) F. Preventive Dentistry-Operative Assistants (GRP486, N=15) G. Orthodontic Assistants (GRP477, N...signs other than blood pressure Assist in emergency procedures, such as managing syncope or providing oxygen to patient Perform surgical evacuation

  16. Antitrombotisk behandling ved iskaemisk apopleksi og transitorisk cerebral iskaemi

    DEFF Research Database (Denmark)

    Overgaard, Karsten; Poulsen, Tina Svenstrup; Husted, Steen E

    2007-01-01

    includes anticoagulation in patients with cardioembolic stroke and antiplatelet agents aspirin possibly combined with dipyridamole or clopidogrel alone in patients with non-cardioembolic stroke. Other individual risks may modify this treatment regimen. Udgivelsesdato: 2007-Oct-1......In acute ischemic stroke and transient ischemic attack (TIA), aspirin is recommended to all patients (except immediately following thrombolysis). Heparin and anticoagulant therapy using vitamin K antagonists should be avoided in the acute phase. Secondary preventive antithrombotic treatment...

  17. HIV kan og skal behandles samtidig med tuberkulose

    DEFF Research Database (Denmark)

    von der Maase, Sarah; Gerstoft, Jan; Wejse, Christian

    2014-01-01

    The proper timing of antiretroviral therapy (ART) to HIV-patients co-infected with tuberculosis has been debated. We review three studies on this matter. One study found a significant reduced mortality for patients with CD4+ T-cell counts (CD4+) ≤ 200 per mm3 who received ART early, whereas...... the other two studies found this difference for patients with CD4+ HIV after the initiation of ART....

  18. Kognitive forstyrrelser ved depression - betydning for behandling og prognose

    DEFF Research Database (Denmark)

    Ravnkilde, Barbara; Bruun, Louise Meldgaard; Videbech, Poul

    2007-01-01

    Depression is often accompanied by cognitive disturbances, and by focusing on these deficits practitioners can obtain important information about the status of the disease and the prognosis of the patient. From this perspective, patients may also gain useful insight into their own condition. Medi....... Medical and psychological treatment interventions can be applied on different levels particularly in relation to the cognitive symptoms of depression. Udgivelsesdato: 2007-Apr-16......Depression is often accompanied by cognitive disturbances, and by focusing on these deficits practitioners can obtain important information about the status of the disease and the prognosis of the patient. From this perspective, patients may also gain useful insight into their own condition...

  19. Udvikling af CO2 neutralt byrumsarmatur

    DEFF Research Database (Denmark)

    Poulsen, Peter Behrensdorff; Dam-Hansen, Carsten; Corell, Dennis Dan

    Denne rapport indeholder en beskrivelse af arbejdet udført i og resultaterne af forsknings- og udviklingsprojektet ” Udvikling af CO2 neutralt byrumsarmatur” og udgør slutrapportering for dette projekt.......Denne rapport indeholder en beskrivelse af arbejdet udført i og resultaterne af forsknings- og udviklingsprojektet ” Udvikling af CO2 neutralt byrumsarmatur” og udgør slutrapportering for dette projekt....

  20. Anmeldelse af World Drug Report 2005

    DEFF Research Database (Denmark)

    Møller, Kim

    2005-01-01

    Internationale udfordringer i spændingsfeltet mellem organiseret kriminalitet og narkotika. Værdien af det illegale narkotikamarked. Skabelsen af et Illicit Drug Index. Ny organisationsstruktur bag udgivelsen af denne WDR. Udgivelsesdato: December......Internationale udfordringer i spændingsfeltet mellem organiseret kriminalitet og narkotika. Værdien af det illegale narkotikamarked. Skabelsen af et Illicit Drug Index. Ny organisationsstruktur bag udgivelsen af denne WDR. Udgivelsesdato: December...

  1. Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial

    Science.gov (United States)

    Breithardt, Günter; Baumgartner, Helmut; Berkowitz, Scott D.; Hellkamp, Anne S.; Piccini, Jonathan P.; Stevens, Susanna R.; Lokhnygina, Yuliya; Patel, Manesh R.; Halperin, Jonathan L.; Singer, Daniel E.; Hankey, Graeme J.; Hacke, Werner; Becker, Richard C.; Nessel, Christopher C.; Mahaffey, Kenneth W.; Fox, Keith A. A.; Califf, Robert M.

    2014-01-01

    Aims We investigated clinical characteristics and outcomes of patients with significant valvular disease (SVD) in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial. Methods and results ROCKET AF excluded patients with mitral stenosis or artificial valve prostheses. We used Cox regression to adjust comparisons for potential confounders. Among 14 171 patients, 2003 (14.1%) had SVD; they were older and had more comorbidities than patients without SVD. The rate of stroke or systemic embolism with rivaroxaban vs. warfarin was consistent among patients with SVD [2.01 vs. 2.43%; hazard ratio (HR) 0.83, 95% confidence interval (CI) 0.55–1.27] and without SVD (1.96 vs. 2.22%; HR 0.89, 95% CI 0.75–1.07; interaction P = 0.76). However, rates of major and non-major clinically relevant bleeding with rivaroxaban vs. warfarin were higher in patients with SVD (19.8% rivaroxaban vs. 16.8% warfarin; HR 1.25, 95% CI 1.05–1.49) vs. those without (14.2% rivaroxaban vs. 14.1% warfarin; HR 1.01, 95% CI 0.94–1.10; interaction P = 0.034), even when controlling for risk factors and potential confounders. In intracranial haemorrhage, there was no interaction between patients with and without SVD where the overall rate was lower among those randomized to rivaroxaban. Conclusions Many patients with ‘non-valvular atrial fibrillation’ have significant valve lesions. Their risk of stroke is similar to that of patients without SVD after controlling for stroke risk factors. Efficacy of rivaroxaban vs. warfarin was similar in patients with and without SVD; however, the observed risk of bleeding was higher with rivaroxaban in patients with SVD but was the same among those without SVD. Atrial fibrillation patients with and without SVD experience the same stroke-preventive benefit of oral anticoagulants. PMID:25148838

  2. 非瓣膜性房颤患者支架植入术后的抗栓策略%Antithrombotic Strategies of the Patients with Non-Valvular AF after PCI

    Institute of Scientific and Technical Information of China (English)

    冯莹

    2014-01-01

    目的:观察房颤患者经皮冠状动脉介入术( post-percutaneous coronary intervention ,PCI)后使用三联疗法( triple therapy ,TT)即华法林+双联抗血小板疗法( dual antiplatelet therapy ,DAPT)的安全性及有效性。方法:这是一项单中心、回顾性研究。主要复合事件包括死亡、缺血性卒中或短暂性脑缺血发作;胃肠道出血、颅内出血。结果:房颤PCI术后患者中,22例接受TT,13例接受DAPT。随访6个月。 TT组CHADS2评分较高,较年长,男性较多。 CHADS2评分值>2分,TT显著减少缺血事件。但TT组复合出血事件增多。 CHADS2评分值>2分的净临床获益(net clinical benefit,NCB)为正值。结论:NCB表明CHADS2评分值>2分的患者使用TT有明显获益。 CHADS2评分可作为房颤PCI术后患者抗栓策略的评估工具。%Objective:To determine the safety and efficacy of triple therapy ( TT): warfarin with dual antiplatelet therapy ( DAPT) for treating patients with atrial fibrillation ( AF) in post -percutaneous coronary intervention (PCI).Methods:This was a single -centre,retrospective study.Primary composite destination event were death , ischemic stroke , or transient ischemic attack; gastrointestinal bleeds , intracerebral hemorrhage.Results:In post-PCI patients with AF,22 received TT,13 received DAPT.Mean follow-up was 6 months.The TT group had a higher CHADS2 score,and older,much more male.CHADS2 score >2, TT decreased ischemic events significantly , but with composite bleeding events were increasing .When CHADS 2 score >2 , Net clinical benefit ( NCB ) was in positive value .Conclusion:NCB declares that patient with CHADS2 score >2 is beneficial to receive TT .CHADS2 score may be used to determine optimal antithrombotic therapy for patients with Af after PCI .

  3. Digitalisering af det eksisterende byggeri

    DEFF Research Database (Denmark)

    Sørensen, Nils Lykke; Øien, Turid Borgestrand

    2010-01-01

    Digitalisering af det eksisterende byggeri er en vanskelig og uendelig opgave. Det giver kun mening at digitalisere eksisterende byggeri, når man har et konkret behov, og da kun at indhente og lagre de informationer, som man strategisk eller konkret har behov for. Erhvervs og Byggestyrelsen har...... iværksat en analyse af strategier for digitalisering af det eksisterende byggeri. I forbindelse hermed vil denne rapport undersøge problemerne og potentialerne ved at digitalisere den eksisterende bygningsmasse, både hvad angår hvilke dele heraf der er relevant at digitalisere, til hvilket niveau, samt de...

  4. Modellering af elforbrug til netanalyse

    DEFF Research Database (Denmark)

    Østergaard, Jacob

    I denne rapport undersøges mulighederne for at etablere en model for elforbruget, der kan anvendes ved analyser af det østdanske transmissionsnet. Rapporten henvender sig til ingeniører og beslutningstagere, der ønsker viden om betydningen af en nøjagtig elforbrugsmodel og om mulighederne for i p...... simuleringsresultater med mindre usikkerhed, og der opnås en integration mellem eksisterende systemer, idet data fra en række systemer bl.a. Panda, elforbrugsprognoser, elforbrugspaneler og stationsprognoser kan udnyttes til etableringen af en model....

  5. Graviditet i livmoderhalsen kan behandles konservativt med methotrexat

    DEFF Research Database (Denmark)

    Sørensen, Marie; Clausen, Helle Vibeke

    2011-01-01

    Two cases of cervical ectopic pregnancy after in vitro fertilization embryo transfer were managed conservatively. One living cervical ectopic pregnancy was treated with intra-amniotic and systemic injection of methotrexate, and the other cervical ectopic pregnancy with a fetal pole was treated...... with systemic methotrexate. The patient with the living cervical ectopic pregnancy had stable vital signs during the period of treatment. The patient with the fetal pole was admitted with heavy vaginal bleeding and anaemia and was stabilised before treatment was initiated. She was stable throughout...

  6. En beskrivelse af tidligere stofmisbrugere

    DEFF Research Database (Denmark)

    Hecksher, Dorte

    2004-01-01

    Artiklen fokuserer på en del af et sample fra en større opfølgningsundersøgelse af døgnbehandlingsindsatsen overfor stofmisbrugere i Danmark. Formålet med artiklen er at beskrive den stoffri gruppe forud for indskrivning i døgnbehandling og i de første to år efter udskrivning fra døgnbehandling. ...

  7. Implementering af MultifunC

    DEFF Research Database (Denmark)

    Henze-Pedersen, Sofie; Kohl, Katrine Syppli; Oldrup, Helene

    (MultifunC), som allerede havde vist lovende resultater i Norge og Sverige. I 2011 og 2012 åbnede to danske MultifunC-institutioner derfor i henholdsvis København og Aarhus. Denne rapport undersøger, hvordan implementeringen af MultifunC-programmet er forløbet i Danmark. Undersøgelsen viser, at ingen af de...... to danske institutioner lykkedes med at implementere MultifunC tilfredsstillende i løbet af implementeringsperioden. Det har fx været vanskeligt at implementere det tætte tværfaglige samarbejde mellem medarbejdere med forskellige fagprofessionelle baggrunde, som behandlingsprogrammet indebærer. Det har...... desuden været særdeles vanskeligt for de danske MultifunC-institutioner at få etableret det eksterne samarbejde med de sociale myndigheder i kommunerne, politiet, skoler og praktiksteder samt fritidstilbud i nærområdet, som også er en væsentlig del af behandlingsprogrammet. Undersøgelsen af finansieret af...

  8. På sporet af de gyldne opskrifter?

    DEFF Research Database (Denmark)

    Poulfelt, Flemming

    2015-01-01

    Børsen Ledelse. Markedet for kogebøger er stort. For der produceres hvert år et hav nye af slagsen. Nogle udgives af kendte kokke, nogle af særlige eksperter inden for kost og motion, og andre af personer, der har en ægte interesse inden for gastronomi og mad. På ledelsesområdet findes en...

  9. Demokratiseringen af den politiske diskurs i Polen

    DEFF Research Database (Denmark)

    Arnfast, Juni Søderberg

    1999-01-01

    Gennem en analyse af brugen af personlige pronominer i politiske tekster fra udvalgte, polske medier diskuteres forandringerne i den polske, politiske diskurs gennem 1980'erne. Det påvises at det kommunistiske styres anvendelse af pronominet 'vi' skifter konnotationer i retning af en mindre ideol...

  10. Kants Kritik af dømmekraften

    DEFF Research Database (Denmark)

    Introduktion til Kants Kritik af dømmekraften bestående af otte artikler, der følger værkets egen tematiske opbygning......Introduktion til Kants Kritik af dømmekraften bestående af otte artikler, der følger værkets egen tematiske opbygning...

  11. Dimensionering af rørisolering

    DEFF Research Database (Denmark)

    Olufsen, P.

    Meddelelsen gennemgår metoderne til dimensionering af termisk isolering af tekniske installationer i bygninger med hovedvægten på isolering af rør og beholdere i varme- og brugsvandsanlæg. Grundlaget for opstilling af mindstekrav til rørisolering diskuteres og der sammenlignes med tilsvarende...

  12. Overvejelser vedr. effektvurdering af det Digitale Sygehus

    DEFF Research Database (Denmark)

    Andersen, Povl Erik Rostgård; Wit, Camilla Kølsen de

    2001-01-01

    Nærværende skrift indeholder en beskrivelse af de overvejelser og planer, der er lavet på projektet 'Effektvurdering af Det Digitale Sygehus' medio dec. 2001.......Nærværende skrift indeholder en beskrivelse af de overvejelser og planer, der er lavet på projektet 'Effektvurdering af Det Digitale Sygehus' medio dec. 2001....

  13. Betydningen af pesticider for forekomsten af vilde bier

    DEFF Research Database (Denmark)

    Bruus, Marianne; Dupont, Yoko Luise; Grant, Ruth;

    Både i Danmark og andre steder er der observeret en nedgang i de insekter, der bestøver landmandens afgrøder og de vilde planter. Tilbagegangen falder sammen med, at landbrugsdriften er blevet mere intensiv, og anvendelsen af pesticider er øget. Vi ved imidlertid ikke, hvilken rolle pesticiderne...... vigtige for bestøvningen af fx kløver og mange vilde planter. Da humlebier og andre vilde bier har en anden adfærd og placerer deres reder andre steder end honningbierne, er det ikke givet, at de er beskyttet mod pesticideksponering, selv om honningbierne er. I pilotprojektet ”Betydningen af pesticider...... for forekomsten af vilde bier og honningbier” har Aarhus Universitet på to landbrugsbedrifter gennemført en indledende undersøgelse af, om humlebier udsættes for pesticider i danske landbrugsområder. Humlebistader blev sat ud i to værkstedsområder (ved Fensten og Rodstenseje syd for Odder), hvor driftsformen...

  14. Effekter ved udlicitering af offentlige opgaver

    DEFF Research Database (Denmark)

    Petersen, Ole Helby; Hjelmar, Ulf; Vrangbæk, Karsten;

    2014-01-01

    Denne rapport præsenterer resultaterne af en systematisk forskningsoversigt over studier af effekter af udlicitering publiceret i perioden 2011-2014. Forskningsoversigten opdaterer en AKF-rapport fra 2011, som gennemgik publicerede undersøgelser af effekter ved udlicitering i perioden 2000-2011 (......-2014. Indsamlingen og vurderingen af studier er afsluttet d. 27. oktober 2014, hvilket betyder, at studier udgivet efter denne dato ikke indgår i forskningsoversigten....

  15. VOIAS – et stemme-assessmentredskab til vurdering af klientens psykiske tilstand og terapeutiske proces, – en undersøgelse af dens kliniske relevans fra et case-perspektiv

    Directory of Open Access Journals (Sweden)

    Sanne Storm

    2016-12-01

    Full Text Available VOIAS er et stemme-assessmentredskab udviklet i forskningsprojektet “Research into the development of voice assessment in music therapy” (Storm 2013. Motivationen til at udvikle et stemmeassessmentredskab til musikterapi udspringer fra mine erfaringer i klinisk praksis og som medlem af et tværfagligt behandler- og udredningsteam. Igennem mange år har jeg anvendt “Psykodynamisk stemmeterapi” som en metode og tilgang til at imødekomme klientens behov for blandt andet at håndtere angst, lindre depression eller støtte en indre oplevelse af centrering for klienter med bipolare lidelser. Psykodynamisk stemmeterapi er en metode og tilgang, som over mange år er blevet mere og mere specifik og konkret, og som i dag anvendes meget struktureret og analytisk i klinisk praksis. Det ontologiske og epistemologiske fundament, som Psykodynamisk stemmeterapi hviler på, er en meget betydningsfuld del af den psykologiske og teoretiske forståelse af det terapirettede krop- og stemmearbejde (Storm, 2007, 2013. En af grundstenene i metoden og tilgangen er musikterapeutens lytteperspektiver (Pedersen, 2000; Storm, 2007, 2013. Lytteperspektiverne omhandler at lytte og orientere sig ud fra klientens stemmeudtryk alene. Ved at lytte til den menneskelige stemme ud fra et udvidet sansemæssigt og kropsligt baseret lytteperspektiv er det muligt for terapeuten og for forskeren at indhente informationer om klienten og dennes aktuelle psykiske tilstand – informationer, der både har relevans for klienten selv og musikterapeuten i den aktuelle terapisituation, samt relevans for hele teamet involveret i behandlingen af klienten. Det er min erfaring gennem mange års klinisk praksis, at det kan være utrolig vanskeligt at videregive informationer indsamlet i musikterapien, så de kan forstås og anvendes af et tværfagligt team. Samtidig er der et behov for at kunne formidle informationerne fra musikterapien letforståeligt, kort og præcist, at kunne dokumentere

  16. Thalidomidbehandling af gastrointestinal angiodysplasi

    DEFF Research Database (Denmark)

    Bélard, Erika; Foss, Catherine H; Christensen, Lisbeth Ambrosius;

    2009-01-01

    Patients with obscure recurrent intestinal bleeding refractory to standard treatment are a major clinical challenge. The bleeding is often a result of angiodysplasia. Most patients undergo numerous diagnostic and therapeutic procedures. In this article we present two cases with no response to sta...... to standard treatment, but who were successfully treated with Thalidomide. Udgivelsesdato: 2009-Nov...

  17. Domesticeringen af Ford i Danmark

    DEFF Research Database (Denmark)

    Wagner, Michael

    Det amerikanske automobilfirma Ford Motor Company med hovedkvarter i Detroit begyndte at drive forretning i Danmark omkring 1906. De første aktiviteter blev konsolideret samme år ved udnævnelsen af motorforhandleren F. Bülow & Co. til salgsagent i Danmark og importør af Ford automobiler til det...... skandinaviske marked. Dermed havde Ford tidligt fået et stærkt fodfæste i Nordeuropa, som udviklingen i salget af Ford autobiler de næste årtier til fulde skulle demonstrere. Ford Motor Company er i dag den fjerde største bilproducent på verdensmarkedet, men går man tilbage til 1920'rne var selskabet førende...... med en markedsandel på mere end 50%. En position som Ford måtte afgive til General Motors i løbet af årtiet. I Danmark var mere end hvert andet indregistreret automobil i 1930 antageligt af mærket Ford, og helt frem til verdenskrigens udbrud var Ford Motor Company et brand, som spillede en meget...

  18. Brug af alternativ isolering i forbindelse med renovering af ældre etageejendomme

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2003-01-01

    Resume af rapport om praktiske erfaringer med brug af alternative isoleringsmaterialer i en renoveringsopgave, udarbejdet af Byfornyelse København m.fl. under Energistyrelsens udviklingsprogram "Miljø- og arbejdsmiljøvenlig isolering"...

  19. Reduktionen af satsen for selskabsskat gør en ændring af creditreglerne aktuel

    DEFF Research Database (Denmark)

    Rønfeldt, Thomas; Werlauff, Erik

    2013-01-01

    Artiklen analyserer sammenhængen mellem satsen for selskabsskatten og maksimeringen af creditlempelsen ved aktivitet i udlandet. Der argumenteres for, at en nedsættelse af selskabsskatten aktualoiserer behovet for en gfennemgribende reform af reglerne om maksimeret credit.......Artiklen analyserer sammenhængen mellem satsen for selskabsskatten og maksimeringen af creditlempelsen ved aktivitet i udlandet. Der argumenteres for, at en nedsættelse af selskabsskatten aktualoiserer behovet for en gfennemgribende reform af reglerne om maksimeret credit....

  20. Implementering af drift i byggeri

    DEFF Research Database (Denmark)

    Damgaard, Torben; Erichsen, Pia Bruun

    På trods af, at der løbende er udgivet materiale der argumenterer for at tænke drift ind i byggeprocesser, er der problemer med, at det faktisk sker. Undersøgelser viser, at forskellige barrierer kan være årsag til problemerne. Disse barrierer kan opstilles inden for følgende kategorier: Projekt...... med i byggeriet. Som følge af dette skal der løbende skabes nye relationer mellem parterne, og der skal arbejdes sammen på nye måder. De forskellige barrierer syntes at være mest fremtrædende ved offentlige byggerier, men også private innovative byggerier er præget af barriererne. Der er flere...

  1. Styring af international transfer pricing

    DEFF Research Database (Denmark)

    Reuther, Peter; Rossing, Christian Plesner

    2011-01-01

    Nærværende artikel introducerer international transfer pricing, dels som et skatteretligt fænomen og dels som et værktøj til planlægning og økonomisk styring af koncernforbundne selskaber i en multinational virksomhed (MNV). Med udgangspunkt i en case-analyse af MNV’en gives der et konkret eksempel...... international transfer pricing i betragtning, når økonomiske styringssystemer i en MNV skal anvendes til planlægning og opfølgning....

  2. På sporet af den tabte sans

    DEFF Research Database (Denmark)

    Nielsen, Thomas Rosendal

    2014-01-01

    Analyse af en workshop om interaktive strategier i børneteater for børn. Workshoppen fandt sted på Dramatikkens hus i Oslo og blev ledet af Sara Topsøe-Jensen, kunstneriske leder af teatret Carte Blanche.......Analyse af en workshop om interaktive strategier i børneteater for børn. Workshoppen fandt sted på Dramatikkens hus i Oslo og blev ledet af Sara Topsøe-Jensen, kunstneriske leder af teatret Carte Blanche....

  3. Fiktionen, der var ude af sig selv

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    2007-01-01

    På baggrund af en analyse af Lars Frosts roman Smukke biler efter krigen (2004) reflekterer jeg over fiktionen som på én gang selvberoende og selvnedbrydende størrelse, og der henvises til Adornos æstetik som en mulig teoretisk ramme for begribelsen af dette tilsyneladende paradoks.......På baggrund af en analyse af Lars Frosts roman Smukke biler efter krigen (2004) reflekterer jeg over fiktionen som på én gang selvberoende og selvnedbrydende størrelse, og der henvises til Adornos æstetik som en mulig teoretisk ramme for begribelsen af dette tilsyneladende paradoks....

  4. En sammenligning af selvstændighedsbegrebet for Assessment of Motor and Process Skills (AMPS) og Barthel Index (BI-100) – for patienter indlagt på apopleksi afsnit

    DEFF Research Database (Denmark)

    Lauridsen, Sussi

    2008-01-01

    Ergoterapeuter arbejder ud fra en overbevisning om, at menneskelig livskvalitet betinges af muligheden for at deltage i daglige aktiviteter, den enkelte selv finder betydningsfulde. Aktivitetsudførelsen afhænger af muligheder og begrænsninger i omgivelserne, i personens evner, rutiner og vaner samt...

  5. Forebyggelse af proteseinfektioner

    DEFF Research Database (Denmark)

    Jørgensen, Peter Holmberg; Gromov, Kirill; Søballe, Kjeld

    2007-01-01

    Prosthetic infection is a feared complication to surgery with alloplastics and has a high degree of comorbidity. Prophylaxis is concentrated on commonly-accepted hygienic behaviour, optimization of the patient's general health status, peri-operative antibiotics (one dose before surgery and three ...... doses during the first 24 hours postoperatively) and antibiotic loaded cement. Laminary flow reduces the risk of prosthesis infection but there is no clear evidence of any effect to concomitant antibiotic prophylaxis. Udgivelsesdato: 2007-Nov-26...

  6. Af materialitet er du kommet

    DEFF Research Database (Denmark)

    Skiveren, Tobias; Gregersen, Martin

    2015-01-01

    På baggrund af bogen "Den materielle drejning. En (ny) optik i og på aktuel dansk litteratur", der udkommer i 2016, skitserer artiklen, hvordan en filosofisk-teoretisk nyorientering under overskriften "den materielle drejning" i øjeblikket udkrystalliserer sig på en henholdsvis økokritisk, posthu......, posthuman og kropsmaterialistisk strømning i dansk samtidslitteratur....

  7. Udvikling af ledelse via ledelseskoncepter

    DEFF Research Database (Denmark)

    Frimann, Søren; Thomassen, Anja Overgaard; Keller, Hanne Dauer

    I denne artikel beskæftiger vi os med, hvordan ledelse kan udvikles i spændingsfeltet mellem udefrakommende krav om mere fælles fodslag i ledelsen og den enkelte leders behov for at tilpasse sin ledelsesstil til den aktuelle kontekst. Konkret ser vi nærmere på, hvordan der blandt en gruppe af led...

  8. Virksomhedernes opfattelse af arbejdsmarkedets "restgrupper"

    DEFF Research Database (Denmark)

    Larsen, Christian Albrekt

    2010-01-01

    Artiklen beskriver, hvorledes danske arbejdsgivere opfatter ældre ledige, ledige indvandrere og ledige med lang forudgående ledighed. Det teoretiske udgangspunkt er, at arbejdsmarkedets fundamentale informationsproblemer fører til brug af statistisk diskrimination og frygt for «lemons». Analyserne...

  9. Signalement af en tabers temperament

    DEFF Research Database (Denmark)

    Holm, Claus

    2009-01-01

    En moderne taber tager ting for tungt, benytter sig ikke nok af glemslens nådegave og har vanskeligt ved at finde en lykkelig fortælling om fortiden. Derfor siger vi i dag: Tag en slapper, tag en pille og tag nogle samtaler....

  10. Forskningsoversigt - Effekterne af Cooperative Learning

    DEFF Research Database (Denmark)

    Larsen, Lea Lund

    Kan Cooperative Learning - en undervisningsform hvor lærerens tid ved tavlen mindskes og hvor de lærende samarbejder om stoffet - maksimere de lærendes indlæring og medvirke til en forbedring af deres interpersonelle og kommunikative kompetencer, samt øge deres motivation for læring? Den megen...

  11. Patentering af det humane genom

    DEFF Research Database (Denmark)

    Sommer, Tine

    2004-01-01

    Direktiv 98/44/EF om retlig beskyttelse af bioteknologiske opfindelser blev gennemført i dansk ret med ikrafttrædelse den 30. juli 2000. Direktivet indeholder i artikel 5 en central bestemmelse som giver adgang til patent på humane gener. I artikel 5, stk. 3, er indføjet et skærpet krav til...

  12. Bliver seksualitetsforskningen lykkelig af moralismeanklager?

    DEFF Research Database (Denmark)

    Frederiksen, Maja Bissenbakker

    2010-01-01

    Anmeldelse: ‘Piger bliver ikke lykkelige af analsex’ er underholdende og sine steder forstemmende læsning om de problematiske måder, hvorpå offentlige debatter de seneste år har gjort seksualitet til genstand for en overvældende bekymring og deraf følgende krav om regulering og kontrol"...

  13. Domesticeringen af Ford i Danmark

    DEFF Research Database (Denmark)

    Wagner, Michael

    2011-01-01

    Det amerikanske automobilfirma Ford Motor Company (1903) med hovedkvarter i Detroit begyndte at drive forretning i Danmark omkring 1906. Dermed havde Ford tidligt fået et stærkt fodfæste i Nordeuropa, som udviklingen i salget af Ford automobiler de næste årtier til fulde skulle demonstrere...

  14. Reformering af vejforvaltning i Afrika

    DEFF Research Database (Denmark)

    Kristiansen, Jørgen

    2004-01-01

    I 1980´erne skete der et hurtigt forfald af vejnettet i mange lande i Afrika syd for Sahara. Både Verdensbanken, EU og de bilaterale donorer blev klar over, at nye institutionelle løsninger var nødvendige, hvis udviklingen skulle vendes. I 1995 blev der under det såkaldte "Road Management...

  15. Fluoridering af drikkevandet i Danmark?

    DEFF Research Database (Denmark)

    Arvin, Erik; Spliid, Henrik; Bruvo, M.;

    2010-01-01

    Første gang sammenhængen mellem caries (huller i tænderne) og fluoridindholdet i drikkevand blev diskuteret i vandværkskredse i Danmark var ved årsmødet i 1958. Her blev det oplyst, at fluorid i drikkevand beskytter mod caries, men man konstaterede også, at der nok ikke var stemning for fluorid......-tilsætning til drikkevandet (fluoridering). Siden da er emnet ikke taget op. Formålet med dette indlæg er at besvare spørgsmålene: 1. Er der behov for fluoridering af drikkevandet i Danmark? 2. Er der alternativer? Hvordan påvirker blødgøring af vand og andre vandbehandlingsmetoder dental caries hos børn og unge......? Som baggrund herfor vil vi redegøre for resultaterne af et netop afsluttet studium af sammenhængen mellem caries og drikkevandets sammensætning, specielt m.h.t. luoridindholdet og vandets calciumindhold (hårdhed). Undersøgelsen bekræfter, at fluorid i drikkevand i væsentlig grad beskytter mod caries...

  16. På sporet af fremtidens konkurrenceevne

    DEFF Research Database (Denmark)

    Boje Rasmussen, Martin Møller

    2013-01-01

    Michael Porter og Harvard Business School står bag nyt banebrydende initiativ, Social Progress Index, som måler et samfunds evne til at skabe livskvalitet for borgerne. Dette aktualiserer debatten om udviklingen af helt nye konkurrencemodeller. Der er tale om et valg mellem tre forskellige typer...

  17. Case-Studie af Fredericia Battle 1849

    DEFF Research Database (Denmark)

    Konzack, Lars

    2015-01-01

    En gennemgang af hvordan oplevelsesøkomien fungerer diskursivt - med Fredericia Battle 1849 som case.......En gennemgang af hvordan oplevelsesøkomien fungerer diskursivt - med Fredericia Battle 1849 som case....

  18. Udvikling af systemleverancer, parametri og BIM

    DEFF Research Database (Denmark)

    Kortegaard, Per

    2016-01-01

    Seminaret rummede indlæg fra både nogle af projektets tidligere ph.d.-studerende og forskellige kompetente professionelle personer fra forskellige grene af praksis. Seminaret gav samlet et fint billede af status indenfor udviklingen af systemleverancer og deres anvendelse i relation til BIM (Buil...... (Building Information Modeling) nationalt som internationalt. Nærværende publikation og dens PDF-udgave rummer seminarets indlæg og illustrationer.......Seminaret rummede indlæg fra både nogle af projektets tidligere ph.d.-studerende og forskellige kompetente professionelle personer fra forskellige grene af praksis. Seminaret gav samlet et fint billede af status indenfor udviklingen af systemleverancer og deres anvendelse i relation til BIM...

  19. Politisk afmagt og udhuling af frihed

    DEFF Research Database (Denmark)

    Thomsen, Steen

    2015-01-01

    Vi oplever lige nu en politisk handlingslammelse som forudset af den liberale økonom von Hayek.......Vi oplever lige nu en politisk handlingslammelse som forudset af den liberale økonom von Hayek....

  20. Æstetisk tolkning af moderne landbrugslandskaber?

    DEFF Research Database (Denmark)

    Krarup, Jonna Majgaard

    2001-01-01

    Præsentation af del af igangværende ph.d.projekt, titel: landbrugeren som kulturlandskabsforvalter - AAA, DK. I projektet arbejdes der udfra en tese om naturopfattelse som af instrumentiel og formdannende karakter. Det moderne landbrugslandskabs ses således som fysisk og æstetisk udtryk for abstr......Præsentation af del af igangværende ph.d.projekt, titel: landbrugeren som kulturlandskabsforvalter - AAA, DK. I projektet arbejdes der udfra en tese om naturopfattelse som af instrumentiel og formdannende karakter. Det moderne landbrugslandskabs ses således som fysisk og æstetisk udtryk...... for abstrakte og kulturelt definerede holdninger af forholdet mellem menneske og natur - forvaltet af den moderne landbruger. I artiklen fokuseres der på et enkelt landskabselement og dets iboende muligheder for æstetisk erfaring og fortolkning....

  1. Lokal trombolyse af sinustrombose

    DEFF Research Database (Denmark)

    Soll, Nicolai Højmose; Vestergård, Karsten; Nepper-Rasmussen, Jørgen

    2009-01-01

    A 16-year-old girl was diagnosed with widely distributed dural sinus thrombosis (DST) and a haemorrhagic infarct in the left parietal lobe. Despite of heparin treatment, pronounced aggravation of symptoms was observed. Through a femoral vein approach a micro-catheter was advanced into the superior...... sagittal sinus and rt-PA was infused slowly, directly into the thrombus over 24 hours. A follow up angiogram showed recanalisation of sinus. The patient recovered almost completely, with only few remaining cognitive symptoms. This treatment remains experimental, but should be kept in mind for DST...

  2. Pulmonale konsekvenser af hashrygning

    DEFF Research Database (Denmark)

    Pfeifer, Andreas Klaus; Lange, Peter

    2006-01-01

    Based on previously published studies, this review describes the pulmonary consequences of marijuana smoking. Smoking of marijuana is significantly associated with chronic bronchitis (cough and phlegm), but it has not been firmly established whether it also leads to a reduction in lung function....... Both epidemiological studies and case reports suggest that regular smokers of marijuana have a higher risk of developing malignancies in both the upper and lower airways. Smoking of marijuana contaminated with fungus spores has been reported to lead to pulmonary aspergillus infections...... in immunocompromised patients, and sharing of marijuana water pipes has been associated with transmission of tuberculosis....

  3. Sygeplejestuderendes brug af portfolio i klinisk undervisning

    DEFF Research Database (Denmark)

    Hjorth, Anne Charlotte Overgaard; Bruhn, Helle

    2014-01-01

    Brugen af portfolio var mangelfuld, men et udviklingsprojekt i samarbejde med den kommunale sygepleje motiverede både sygeplejestuderende og kliniske vejledere til at anvende læringsdelen af portfolio aktivt.......Brugen af portfolio var mangelfuld, men et udviklingsprojekt i samarbejde med den kommunale sygepleje motiverede både sygeplejestuderende og kliniske vejledere til at anvende læringsdelen af portfolio aktivt....

  4. Kortlægning af unge

    DEFF Research Database (Denmark)

    Skou, Carl Verner

    2009-01-01

    Computerprogram til Windows XP/Vista platformen til indberetning af unge under 18 år til registering af stofmisbrug og sociale data. Udgave: 1.0.1.1 Udgivelsesdato: 01-01-2009......Computerprogram til Windows XP/Vista platformen til indberetning af unge under 18 år til registering af stofmisbrug og sociale data. Udgave: 1.0.1.1 Udgivelsesdato: 01-01-2009...

  5. Udviklingen af rumopfattelsen 1600-2000

    DEFF Research Database (Denmark)

    Brock, Steen

    2010-01-01

    Hovedtræk af rumopfattelsens idehistorie fra Descartes til Wittgenstein med speciel vægt på Kant, værkbegrebet, modelbegrebet og den fænomenologiske opfattelse af rummet som handlingens sted......Hovedtræk af rumopfattelsens idehistorie fra Descartes til Wittgenstein med speciel vægt på Kant, værkbegrebet, modelbegrebet og den fænomenologiske opfattelse af rummet som handlingens sted...

  6. Måling af mineraluldsfibre i indeklimaet

    DEFF Research Database (Denmark)

    Nielsen, O.; Andersen, N.E.; Bredsdorff, P.;

    Rapporten beskriver resultaterne af målinger af luftbårne mineraluldsfibre, luftbårne ikke-mineraluldsfibre, luftbårent støv samt sedimenterede mineraluldsfibre i 105 lokaler med forskellige loftstyper. Resultaterne vil bl.a. kunne anvendes i forbindelse med vurdering af mulighederne for reduceri...

  7. Registrering af biometriske og biologiske personoplysninger

    DEFF Research Database (Denmark)

    Blume, Peter Erik; Herrmann, Janne Rothmar

    2009-01-01

    Med udgangspunkt i menneskeretsdomstolens Marper dom drøftes i artiklen indretningen af dansk rets regler om registrering af fingeraftryk og dna-profil med tilhørende biologisk materiale, og om dommen nødvendiggør ændringer af disse regler....

  8. Forskningsbibliotekernes bidrag til produktion af evidensbaseret viden

    DEFF Research Database (Denmark)

    Johannsen, Carl Gustav

    2012-01-01

    Artiklen indeholder en karakteristik af evidensbevægelsens metodemæssige grundlag, hvor det pointeres, at evidensbevægelsen er et forgrenet, internationalt samrabejde om produktion og formidling af systematiske reviews vedr. effektiviteten af offentlige indsatser, interventioner, som hovedformål....

  9. Regulering af jødiske kroppe

    DEFF Research Database (Denmark)

    Schleicher, Marianne

    2014-01-01

    på teori dels af Michel Foucault om, hvordan kultur sikrer sin egen overlevelse ved at indsamle viden om bl.a. kroppe med henblik på at regulere brugen af dem, dels af Judith Butler, der bl.a. forklarer, hvordan kultur trods alt er åben for såkaldt subversion, idet det bidrager til at udvide og...

  10. Registrering og Benchmarking af Modus 2 Forskning

    DEFF Research Database (Denmark)

    Duus, Henrik Johannsen; Jørgensen, Jens E.

    2004-01-01

    Fremvæksten af modus 2 forskning stiller krav om en revurdering af højere læreanstalters evaluerings- og meriteringspraksis. Den endimensionale prioritering af modus 1 forskning såvel som dennes ligeså endimensionale evaluering via publikationer må afvises som utidssvarende. Som en konsekvens her...

  11. Energioptimering af bæredygtighedscertificeringsprocesserne

    DEFF Research Database (Denmark)

    Christensen, Dorthe Holmberg; Carlsen, Mads; Alon, Shlomo Nevo

    2014-01-01

    Større fokus på bæredygtighedscertificeringer som DGNB har yderligere øget kompleksiteten af designet af bygninger. Introduktionen af teknologier som building information modelling (BIM) og proces metoder som integreret design proces (IDP) kan hjælpe med at reducere kompleksiteten og bedre...

  12. Modelanalyser af mobilitet og miljø

    DEFF Research Database (Denmark)

    Christensen, Linda; Gudmundsson, Henrik

    Begrebet bæredygtig transport diskuteres og ved hjælp af persontrafikmodellen ALTRANS belyses mulighederne for at fremme bæredygtig udvikling gennem en række scenarier. Desuden præsenteres en mere detaljeret analyse af ændringer i CO2-belastningen ved forbedring af den kollektive trafiks servicen...

  13. Dimensionering af indblæsning

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    1974-01-01

    Dimensionering af indblæsningsarmaturer og bestemmelse af luftfordeling i lokaler bygger traditionelt på kendskabet til isotermiske fristråler og vægstråler. Som det fremgår af skitserne i indholdsfortegnelsen, indleder vi også med dette emne. Derefter udsætter vi - skridt for skridt - de ideele...

  14. Fermentering af korn øger fordøjeligheden af næringsstoffer

    DEFF Research Database (Denmark)

    Pedersen, Anni Øyan; Jørgensen, Henry Johs. Høgh; Knudsen, Knud Erik Bach;

    2010-01-01

    Et fordøjelighedsforsøg har vist, at energiværdien af byg og hvede steg ved fermentering. Effekten var størst ved fermentering af byg, hvor fordøjeligheden af organisk stof for enden af tyndtarmen steg statistisk sikkert med 9 %. Ved fermentering af hvede steg fordøjeligheden af organisk stof...... statistisk sikkert med 3 %. Stigningen i energiværdien ved fermentering af korn kunne ikke vises ved foderanalyser (FEsv), hvilket viser, at in vitro-analyserne EFOS og EFOSi ikke kan anvendes til vurdering af effekten af fermentering. Fordøjeligheden af fosfor i foderblandinger baseret på byg eller hvede og...... tilskudsfoder steg statistisk sikkert ved fermentering af kornet. Der blev ikke tilsat mikrobiel fytase. Ved fermentering af byg steg fordøjeligheden af fosfor i foderblandingen fra 32 til 47 %, og ved fermentering af hvede steg fordøjeligheden af fosfor i blandingen fra 43 til 57 %. Fordøjeligheden af fosfor i...

  15. Undersøgelse af kommunernes administration af bygningsreglementets elevatorkrav

    DEFF Research Database (Denmark)

    Grangaard, Sidse

    få dispensationsansøgninger for elevator ved nybyggeri. Undersøgelsen tyder dog på, at nogle bygherrer og rådgivere er opmærksomme på kravet og i nogle tilfælde vælger at disponere bygningen, så der ikke stilles krav om elevator. Ved ombygning og tilbygning oplever langt over halvdelen af kommunerne...

  16. Trafikanalyser af et net af letbaner og BRT i Hovedstaden

    DEFF Research Database (Denmark)

    Nielsen, Otto Anker; Ingvardson, Jesper Bláfoss; Andersen, Jonas Lohmann Elkjær

    Denne rapport gennemgår et projekt for Region Hovedstaden, hvor letbanenet fra forårets opgave for Region Hovedstaden (Nielsen, Ingvardson & Andersen, 2013) blev detaljeret, viderebearbejdet og forbedret, hvorefter der er gennemført beregninger af forskellige varianter med OTM Trafikmodellen. Arb...... og sammenlignes med tidligere net og beregninger, der er blevet gennemført i Trængselskommissionens regi....

  17. Fra Person til Patient

    DEFF Research Database (Denmark)

    Worsøe, Line Brink; Tordsson, Emma Mathilde

    2008-01-01

    I efteråret 2007 gennemførte forfatterne af denne artikel en undersøgelse af fertilitetspatienters kommunikation på nettet. Undersøgelsen var en del af kandidatspecialet i Sprogpsykologi "Fra Person til Patient - en narrativ undersøgelse af fertilitetspatienters kommunikation". Sigtet med special...

  18. Patienters oplevelse af deltagelse i et accelereret operationsforløb efter en kolonoperation. En fænomenologisk undersøgelse

    DEFF Research Database (Denmark)

    Norlyk, Annelise

    2010-01-01

    Lifeworld Research. Participating in the programme involved facing several dilemmas. It was not always easy for the patients to find the strength, courage, and will to comply with the daily regimen because discomfort and vulnerability could undermine their abilities to follow the recommendations...

  19. Måling af diskrimination på baggrund af etnisk oprindelse

    DEFF Research Database (Denmark)

    Jensen, Tina Gudrun; Weibel, Kristina; Tørslev, Mette Kirstine

    Denne rapport sætter fokus på, hvordan man kan måle diskrimination på baggrund af etnisk oprindelse. På baggrund af et studie af tidligere undersøgelser på området og relevant metodelitteratur, søger rapporten at udvikle metoder til valide målinger af diskrimination på baggrund af etnisk oprindel...

  20. Halvering af dagpengeperioden og akutpakken

    DEFF Research Database (Denmark)

    Nilsson, Klara; Holt, Helle

    Formålet med denne undersøgelse er at give et øjebliksbillede af jobcentrenes og a-kassernes beskæftigelsesindsats her og nu. Gennem en række kvalitative interview med medarbejdere fra jobcentre og a-kasser belyses det, hvordan henholdsvis jobcentre og a-kasser har håndteret halveringen af...... at finde et job, hvilket blandt andet har betydet en tidligere og intensiveret indsats overfor de ledige. Den særlige indsats har derfor bidraget med et større fokus og sammenhæng i indsatsen for den enkelte borger gennem blandt andet en personlig jobformidler og fællessamtaler mellem den ledige, a...