WorldWideScience

Sample records for beam therapy facility

  1. Proton beam therapy facility

    International Nuclear Information System (INIS)

    1984-01-01

    It is proposed to build a regional outpatient medical clinic at the Fermi National Accelerator Laboratory (Fermilab), Batavia, Illinois, to exploit the unique therapeutic characteristics of high energy proton beams. The Fermilab location for a proton therapy facility (PTF) is being chosen for reasons ranging from lower total construction and operating costs and the availability of sophisticated technical support to a location with good access to patients from the Chicago area and from the entire nation. 9 refs., 4 figs., 26 tabs

  2. Proton beam therapy facility

    Energy Technology Data Exchange (ETDEWEB)

    1984-10-09

    It is proposed to build a regional outpatient medical clinic at the Fermi National Accelerator Laboratory (Fermilab), Batavia, Illinois, to exploit the unique therapeutic characteristics of high energy proton beams. The Fermilab location for a proton therapy facility (PTF) is being chosen for reasons ranging from lower total construction and operating costs and the availability of sophisticated technical support to a location with good access to patients from the Chicago area and from the entire nation. 9 refs., 4 figs., 26 tabs.

  3. A beam optics study of the biomedical beam line at a proton therapy facility

    International Nuclear Information System (INIS)

    Yun, Chong Cheoul; Kim, Jong-Won

    2007-01-01

    A biomedical beam line has been designed for the experimental area of a proton therapy facility to deliver mm to sub-mm size beams in the energy range of 20-50 MeV using the TRANSPORT/TURTLE beam optics codes and a newly-written program. The proton therapy facility is equipped with a 230 MeV fixed-energy cyclotron and an energy selection system based on a degrader and slits, so that beam currents available for therapy decrease at lower energies in the therapeutic beam energy range of 70-230 MeV. The new beam line system is composed of an energy-degrader, two slits, and three quadrupole magnets. The minimum beam sizes achievable at the focal point are estimated for the two energies of 50 and 20 MeV. The focused FWHM beam size is approximately 0.3 mm with an expected beam current of 20 pA when the beam energy is reduced to 50 MeV from 100 MeV, and roughly 0.8 mm with a current of 10 pA for a 20 MeV beam

  4. Treatment facilities, human resource development, and future prospect of particle beam therapy

    International Nuclear Information System (INIS)

    Tamaki, Tomoaki; Nakano, Takashi

    2015-01-01

    The number of particle beam therapy facilities is increasing globally. Among the countries practicing particle beam therapy, Japan is one of the leading countries in the field with four operating carbon-ion therapy facilities and ten operating proton therapy facilities. With the increasing number of particle beam therapy facilities, the human resource development is becoming extremely important, and there has been many such efforts including the Gunma University Program for Cultivating Global Leaders in Heavy Ion Therapeutics and Engineering, which aimed to educate and train the radiation oncologists, medical physicists, accelerator engineers, and radiation biologists to become global leaders in the field of particle beam therapy. In the future, the benefit and effectiveness of particle beam therapy should be discussed and elucidated objectively in a framework of comprehensive cancer care. (author)

  5. The accelerator facility of the Heidelberg Ion-Beam Therapy Centre (HIT)

    Science.gov (United States)

    Peters, Andreas

    The following sections are included: * Introduction * Beam parameters * General layout of the HIT facility * The accelerator chain in detail * Operational aspects of a particle therapy facility * 24/7 accelerator operation at 335 days per year * Safety and regulatory aspects * Status and perspectives * References

  6. Neutron Therapy Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Neutron Therapy Facility provides a moderate intensity, broad energy spectrum neutron beam that can be used for short term irradiations for radiobiology (cells)...

  7. Opening and construction of facilities in succession for particle beam therapy of cancer

    International Nuclear Information System (INIS)

    Nakano, Takashi; Yamamoto, Kazutaka; Hishikawa, Yoshio; Totoki, Tadahide; Hoshino, Junichi; Aoki, Takashi; Yoshiyuki, Takeshi; Hirabayashi, Masayuki; Nakamura, Fumito

    2011-01-01

    This feature article describes the current state of practical particle beam therapy of cancer, its future prospect, recent opening/construction of its facilities and manufacturers' view with following 9 topics presented by relevant experts. Gunma University (topic 1) started the carbon ion therapy from Mar., 2010, and has treated more than 100 cancer patients to aim the treatment of about 600 patients/year after several years. Fukui Prefectural Hospital Proton Therapy Center (topic 2) started from this March with proton beams for patients with its therapeutic standard, in cooperation with insurance companies and hotels for patients' convenience. Medipolis Proton Therapy and Research Center (Kagoshima Pref.) (topic 3) started this year with proton beams for 13 patients hitherto with reference protocol of Hyogo Ion Beam Medical Center. A new stereotactic irradiation system of proton beams for breast cancer has been developed. Construction of Saga Heavy Ion Medical Accelerator in Tosu (Saga Pref.) (topic 4) began this year to be completed in 2013. Aizawa Hospital (Nagano Pref.) (topic 5) plans to introduce the small-sized proton accelerator-gantry system (Sumitomo Heavy Ind., Ltd.) aiming the practice in 2013. Association for Nuclear Technology in Medicine (topic 6) reports the trends of current and future construction inside/outside Japan. Manufacturers comment their respective business: high-speed scanning irradiation system, next generation handling system of patient and particle beam therapy information system by Toshiba (topic 7); designation of the whole heavy ion beam therapy system (with NIRS), proton beam (as in topic 5) and system of BNCT (boron neutron-capture therapy) (Kyoto Univ.) by Sumitomo Heavy Ind., Ltd. (topic 8); and small-size proton therapeutic machine with 4D tracing capability for patient's movement (Hokkaido Univ.) and with spot-scanning irradiation technique by Hitachi (topic 9). (author)

  8. Primary study for boron neutron capture therapy uses the RSG-GAS beam tube facility

    International Nuclear Information System (INIS)

    Suroso

    2000-01-01

    The minimum epithermal neutron flux as one of the prerequisite of Boron Neutron Capture Therapy (BNCT) is 1.0 x 10 9 n/(cm 2 s) RSG-GAS have 6 beam tube facilities for neutron source, which is one of the beam tube S-2 has a possibility to utilization for BNCT facility. The totally flux neutron measurement in the front of S-2 beam tube is 1.8 x 10 7 n/(cm 2 s). The neutron flux measurement was less than for BNCT minimum prerequisite. Concerning to the flux neutron production in the reactor, which is reach to 2.5 x 10 14 n/(cm 2 s), there for the S-2 beam tube could be used beside collimator modification

  9. Evolution of a beam dynamics model for the transport line in a proton therapy facility

    Science.gov (United States)

    Rizzoglio, V.; Adelmann, A.; Baumgarten, C.; Frey, M.; Gerbershagen, A.; Meer, D.; Schippers, J. M.

    2017-12-01

    During the conceptual design of an accelerator or beamline, first-order beam dynamics models are essential for studying beam properties. However, they can only produce approximate results. During commissioning, these approximate results are compared to measurements, which will rarely coincide if the model does not include the relevant physics. It is therefore essential that this linear model is extended to include higher-order effects. In this paper, the effects of particle-matter interaction have been included in the model of the transport lines in the proton therapy facility at the Paul Scherrer Institut (PSI) in Switzerland. The first-order models of these beamlines provide an approximated estimation of beam size, energy loss and transmission. To improve the performance of the facility, a more precise model was required and has been developed with opal (Object Oriented Parallel Accelerator Library), a multiparticle open source beam dynamics code. In opal, the Monte Carlo simulations of Coulomb scattering and energy loss are performed seamless with the particle tracking. Beside the linear optics, the influence of the passive elements (e.g., degrader, collimators, scattering foils, and air gaps) on the beam emittance and energy spread can be analyzed in the new model. This allows for a significantly improved precision in the prediction of beam transmission and beam properties. The accuracy of the opal model has been confirmed by numerous measurements.

  10. Proton beam characterization in the experimental room of the Trento Proton Therapy facility

    Science.gov (United States)

    Tommasino, F.; Rovituso, M.; Fabiano, S.; Piffer, S.; Manea, C.; Lorentini, S.; Lanzone, S.; Wang, Z.; Pasini, M.; Burger, W. J.; La Tessa, C.; Scifoni, E.; Schwarz, M.; Durante, M.

    2017-10-01

    As proton therapy is becoming an established treatment methodology for cancer patients, the number of proton centres is gradually growing worldwide. The economical effort for building these facilities is motivated by the clinical aspects, but might be also supported by the potential relevance for the research community. Experiments with high-energy protons are needed not only for medical physics applications, but represent also an essential part of activities dedicated to detector development, space research, radiation hardness tests, as well as of fundamental research in nuclear and particle physics. Here we present the characterization of the beam line installed in the experimental room of the Trento Proton Therapy Centre (Italy). Measurements of beam spot size and envelope, range verification and proton flux were performed in the energy range between 70 and 228 MeV. Methods for reducing the proton flux from typical treatments values of 106-109 particles/s down to 101-105 particles/s were also investigated. These data confirm that a proton beam produced in a clinical centre build by a commercial company can be exploited for a broad spectrum of experimental activities. The results presented here will be used as a reference for future experiments.

  11. Epithermal neutron beam design for neutron capture therapy at the Power Burst Facility and the Brookhaven Medical Research Reactor

    International Nuclear Information System (INIS)

    Wheeler, F.J.; Parsons, D.K.; Rushton, B.L.; Nigg, D.W.

    1990-01-01

    Nuclear design studies have been performed for two reactor-based epithermal neutron beams for cancer treatment by neutron capture therapy (NCT). An intermediate-intensity epithermal beam has been designed and implemented at the Brookhaven Medical Research Reactor (BMRR). Measurements show that the BMRR design predictions for the principal characteristics of this beam are accurate. A canine program for research into the biological effects of NCT is now under way at BMRR. The design for a high-intensity epithermal beam with minimal contamination from undesirable radiation components has been finalized for the Power Burst Facility (PBF) at the Idaho National Engineering Laboratory. This design will be implemented when it is determined that human NCT trials are advisable. The PBF beam will exhibit approximately an order of magnitude improvement in absolute epithermal flux intensity over that available in the BMRR, and its angular distribution and spectral characteristics will be more advantageous for NCT. The combined effects of beam intensity, angular distribution, spectrum, and contaminant level allow the desired tumor radiation dose to be delivered in much shorter times than are possible with the currently available BMRR beam, with a significant reduction (factor of 3 to 5) in collateral dose due to beam contaminants

  12. More than 10 years experience of beam monitoring with the Gantry 1 spot scanning proton therapy facility at PSI

    International Nuclear Information System (INIS)

    Lin Shixiong; Boehringer, Terence; Coray, Adolf; Grossmann, Martin; Pedroni, Eros

    2009-01-01

    Purpose: The beam monitoring equipments developed for the first PSI spot scanning proton therapy facility, Gantry 1, have been successfully used for more than 10 years. The purpose of this article is to summarize the author's experience in the beam monitoring technique for dynamic proton scanning. Methods: The spot dose delivery and verification use two independent beam monitoring and computer systems. In this article, the detector construction, electronic system, dosimetry, and quality assurance results are described in detail. The beam flux monitor is calibrated with a Faraday cup. The beam position monitoring is realized by measuring the magnetic fields of deflection magnets with Hall probes before applying the spot and by checking the beam position and width with an ionization strip chamber after the spot delivery. Results: The results of thimble ionization chamber dosimetry measurements are reproducible (with a mean deviation of less than 1% and a standard deviation of 1%). The resolution in the beam position measurement is of the order of a tenth of a millimeter. The tolerance of the beam position delivery and monitoring during scanning is less than 1.5 mm. Conclusions: The experiences gained with the successful operation of Gantry 1 represent a unique and solid background for the development of a new system, Gantry 2, in order to perform new advanced scanning techniques.

  13. More than 10 years experience of beam monitoring with the Gantry 1 spot scanning proton therapy facility at PSI

    Energy Technology Data Exchange (ETDEWEB)

    Lin Shixiong; Boehringer, Terence; Coray, Adolf; Grossmann, Martin; Pedroni, Eros [Center for Proton Therapy, Paul Scherrer Institute, CH-5232 Villigen PSI (Switzerland)

    2009-11-15

    Purpose: The beam monitoring equipments developed for the first PSI spot scanning proton therapy facility, Gantry 1, have been successfully used for more than 10 years. The purpose of this article is to summarize the author's experience in the beam monitoring technique for dynamic proton scanning. Methods: The spot dose delivery and verification use two independent beam monitoring and computer systems. In this article, the detector construction, electronic system, dosimetry, and quality assurance results are described in detail. The beam flux monitor is calibrated with a Faraday cup. The beam position monitoring is realized by measuring the magnetic fields of deflection magnets with Hall probes before applying the spot and by checking the beam position and width with an ionization strip chamber after the spot delivery. Results: The results of thimble ionization chamber dosimetry measurements are reproducible (with a mean deviation of less than 1% and a standard deviation of 1%). The resolution in the beam position measurement is of the order of a tenth of a millimeter. The tolerance of the beam position delivery and monitoring during scanning is less than 1.5 mm. Conclusions: The experiences gained with the successful operation of Gantry 1 represent a unique and solid background for the development of a new system, Gantry 2, in order to perform new advanced scanning techniques.

  14. Overview of colliding beam facilities

    International Nuclear Information System (INIS)

    Herrera, J.C.; Month, M.

    1979-01-01

    A review is presented of the colliding beam facilities in existence today. The major high energy physics facilities around the world are described, and a view is presented of the beam collisions in which the instruments used to make the beams collide and those used to detect the products of particle interactions in the beam overlap region are described

  15. Maximum dose angle for oblique incidence on primary beam protective barriers in the design of medical radiation therapy facilities

    International Nuclear Information System (INIS)

    Fondevila, Damian; Arbiser, Silvio; Sansogne, Rosana; Brunetto, Monica; Dosoretz, Bernardo

    2008-01-01

    Primary barrier determinations for the shielding of medical radiation therapy facilities are generally made assuming normal beam incidence on the barrier, since this is geometrically the most unfavorable condition for that shielding barrier whenever the occupation line is allowed to run along the barrier. However, when the occupation line (for example, the wall of an adjacent building) runs perpendicular to the barrier (especially roof barrier), then two opposing factors come in to play: increasing obliquity angle with respect to the barrier increases the attenuation, while the distance to the calculation point decreases, hence, increasing the dose. As a result, there exists an angle (α max ) for which the equivalent dose results in a maximum, constituting the most unfavorable geometric condition for that shielding barrier. Based on the usual NCRP Report No. 151 model, this article presents a simple formula for obtaining α max , which is a function of the thickness of the barrier (t E ) and the equilibrium tenth-value layer (TVL e ) of the shielding material for the nominal energy of the beam. It can be seen that α max increases for increasing TVL e (hence, beam energy) and decreases for increasing t E , with a range of variation that goes from 13 to 40 deg for concrete barriers thicknesses in the range of 50-300 cm and most commercially available teletherapy machines. This parameter has not been calculated in the existing literature for radiotherapy facilities design and has practical applications, as in calculating the required unoccupied roof shielding for the protection of a nearby building located in the plane of the primary beam rotation

  16. Maximum dose angle for oblique incidence on primary beam protective barriers in the design of medical radiation therapy facilities.

    Science.gov (United States)

    Fondevila, Damián; Arbiser, Silvio; Sansogne, Rosana; Brunetto, Mónica; Dosoretz, Bernardo

    2008-05-01

    Primary barrier determinations for the shielding of medical radiation therapy facilities are generally made assuming normal beam incidence on the barrier, since this is geometrically the most unfavorable condition for that shielding barrier whenever the occupation line is allowed to run along the barrier. However, when the occupation line (for example, the wall of an adjacent building) runs perpendicular to the barrier (especially roof barrier), then two opposing factors come in to play: increasing obliquity angle with respect to the barrier increases the attenuation, while the distance to the calculation point decreases, hence, increasing the dose. As a result, there exists an angle (alpha(max)) for which the equivalent dose results in a maximum, constituting the most unfavorable geometric condition for that shielding barrier. Based on the usual NCRP Report No. 151 model, this article presents a simple formula for obtaining alpha(max), which is a function of the thickness of the barrier (t(E)) and the equilibrium tenth-value layer (TVL(e)) of the shielding material for the nominal energy of the beam. It can be seen that alpha(max) increases for increasing TVL(e) (hence, beam energy) and decreases for increasing t(E), with a range of variation that goes from 13 to 40 deg for concrete barriers thicknesses in the range of 50-300 cm and most commercially available teletherapy machines. This parameter has not been calculated in the existing literature for radiotherapy facilities design and has practical applications, as in calculating the required unoccupied roof shielding for the protection of a nearby building located in the plane of the primary beam rotation.

  17. Getting Ready for Ion-Beam Therapy Research in Austria - Building-up Research in Parallel with a Facility

    International Nuclear Information System (INIS)

    Georg, Dietmar; Knaeusl; Kuess, Peter; Fuchs, Hermann; Poetter, Richard; Schreiner, Thomas

    2015-01-01

    With participation in ion-beam projects funded nationally or by the European Commission (EC), ion-beam research activities were started at the Medical University of Vienna in parallel with the design and construction of the ion-beam center MedAustron in Wiener Neustadt, 50 km from the Austrian capital. The current medical radiation physics research activities that will be presented comprise: (1) Dose calculation and optimization: ion-beam centers focus mostly on proton and carbon-ion therapy. However, there are other ion species with great potential for clinical applications. Helium ions are currently under investigation from a theoretical physics and biology perspective. (2) Image guided and adaptive ion-beam therapy: organ motion and anatomic changes have a severe influence in ion-beam therapy since variations in heterogeneity along the beam path have a significant impact on the particle range. Ongoing research focuses on possibilities to account for temporal variations of the anatomy during radiotherapy. Both during and between fractions also considering temporal variations in tumor biology. Furthermore, research focuses on particle therapy positron emission tomography (PT-PET) verification and the detection of prompt gammas for on-line verification of ion-beam delivery. (3) Basic and applied dosimetry: an end-to-end procedure was designed and successfully tested in both scanned proton and carbon-ion beams, which may also serve as a dosimetric credentialing procedure for clinical trials in the future. (Author)

  18. Electrostatic design and beam transport for a folded tandem electrostatic quadrupole accelerator facility for accelerator-based boron neutron capture therapy

    International Nuclear Information System (INIS)

    Thatar Vento, V.; Bergueiro, J.; Cartelli, D.; Valda, A.A.; Kreiner, A.J.

    2011-01-01

    Within the frame of an ongoing project to develop a folded Tandem-Electrostatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT), we discuss here the electrostatic design of the machine, including the accelerator tubes with electrostatic quadrupoles and the simulations for the transport and acceleration of a high intensity beam.

  19. Electrostatic design and beam transport for a folded tandem electrostatic quadrupole accelerator facility for accelerator-based boron neutron capture therapy.

    Science.gov (United States)

    Vento, V Thatar; Bergueiro, J; Cartelli, D; Valda, A A; Kreiner, A J

    2011-12-01

    Within the frame of an ongoing project to develop a folded Tandem-Electrostatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT), we discuss here the electrostatic design of the machine, including the accelerator tubes with electrostatic quadrupoles and the simulations for the transport and acceleration of a high intensity beam. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Cluster ion beam facilities

    International Nuclear Information System (INIS)

    Popok, V.N.; Prasalovich, S.V.; Odzhaev, V.B.; Campbell, E.E.B.

    2001-01-01

    A brief state-of-the-art review in the field of cluster-surface interactions is presented. Ionised cluster beams could become a powerful and versatile tool for the modification and processing of surfaces as an alternative to ion implantation and ion assisted deposition. The main effects of cluster-surface collisions and possible applications of cluster ion beams are discussed. The outlooks of the Cluster Implantation and Deposition Apparatus (CIDA) being developed in Guteborg University are shown

  1. Beam Characterizations at Femtosecond Electron Beam Facility

    CERN Document Server

    Rimjaem, Sakhorn; Kangrang, Nopadol; Kusoljariyakul, Keerati; Rhodes, Michael W; Saisut, Jatuporn; Thongbai, Chitrlada; Vilaithong, Thiraphat; Wichaisirimongkol, Pathom; Wiedemann, Helmut

    2005-01-01

    The SURIYA project at the Fast Neutron Research Facility (FNRF) has been established and is being commissioning to generate femtosecond electron pulses. Theses short pulses are produced by a system consisting of an S-band thermionic cathode RF-gun, an alpha magnet as a magnetic bunch compressor, and a linear accelerator. The characteristics of its major components and the beam characterizations as well as the preliminary experimental results will be presented and discussed.

  2. Double beam neutron radiography facility

    International Nuclear Information System (INIS)

    Domanus, J.C.

    1977-09-01

    The DR1 reactor at Risoe is used as a neutron source for neutron radiography. In the double-beam neutron radiography facility a neutron flux of an intensity of 1.4 and 1.8 x 10 6 n. cm -2 . s -1 reaches the object to be radiographed. The transport and exposure container used for neutron radiography of irradiated nuclear fuel rods is described, and the exposure technique and procedure are reviewed. The mode by which single neutron radiographs are assembled and assessed is described. This report will be published in the ''Neutron Radiography Newsletter''. (author)

  3. Electron beams in radiation therapy

    International Nuclear Information System (INIS)

    Bruinvis, I.A.D.

    1987-01-01

    Clinical electron beams in interaction with beam flattening and collimating devices are studied, in order to obtain the means for adequate electron therapy. A treatment planning method for arbitrary field shapes is developed that takes the properties of the collimated electron beams into account. An electron multiple-scattering model is extended to incorporate a model for the loss of electrons with depth, in order to improve electron beam dose planning. A study of ionisation measurements in two different phantom materials yields correction factors for electron beam dosimetry. (Auth.)

  4. Radiation therapy facilities in the United States

    International Nuclear Information System (INIS)

    Ballas, Leslie K.; Elkin, Elena B.; Schrag, Deborah; Minsky, Bruce D.; Bach, Peter B.

    2006-01-01

    Purpose: About half of all cancer patients in the United States receive radiation therapy as a part of their cancer treatment. Little is known, however, about the facilities that currently deliver external beam radiation. Our goal was to construct a comprehensive database of all radiation therapy facilities in the United States that can be used for future health services research in radiation oncology. Methods and Materials: From each state's health department we obtained a list of all facilities that have a linear accelerator or provide radiation therapy. We merged these state lists with information from the American Hospital Association (AHA), as well as 2 organizations that audit the accuracy of radiation machines: the Radiologic Physics Center (RPC) and Radiation Dosimetry Services (RDS). The comprehensive database included all unique facilities listed in 1 or more of the 4 sources. Results: We identified 2,246 radiation therapy facilities operating in the United States as of 2004-2005. Of these, 448 (20%) facilities were identified through state health department records alone and were not listed in any other data source. Conclusions: Determining the location of the 2,246 radiation facilities in the United States is a first step in providing important information to radiation oncologists and policymakers concerned with access to radiation therapy services, the distribution of health care resources, and the quality of cancer care

  5. Development of cancer therapy facility of HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Jun, Byung Jin; Hwang, S. Y.; Kim, M. J. and others

    2000-04-01

    Facilities of the research and clinical treatments of neutron capture therapy using HANARO are developed, and they are ready to install. They are BNCT irradiation facility and prompt gamma neutron activatiion analysis facility. Since every horizontal neutron facility of HANARO is long and narrow tangential beam tube, it is analysed that sufficient epithermal neutrons for the BNCT cannot be obtained but sufficient thermal neutrons can be obtained by a filter composed of silicon and bismuth single crystals. Since the thermal neutron penetaration increases significantly when the crystals are cooled, a filter cooled by liquid nitrogen is developed. So as to avoid interference with the reactor operation, a water shutter is developed. The irradiation room is designed for the temporary surgical operation as well. Handling tools to remove activated beam port plug and to install water shutter and filter are developed. The basic structure of the irradiation room is already installed and most of other parts are ready to install. Since no free beam port is available for the prompt gamma neutron activation analysis, a method obtaining almost pure thermal neutrons by the vertical diffraction of extra beam for the polarized neutron spectrometer is developed. This method is confirmed by analysis and experiments to give high enough neutron beam. Equipment and devices are provided to install this facility.

  6. Development of cancer therapy facility of HANARO

    International Nuclear Information System (INIS)

    Jun, Byung Jin; Hwang, S. Y.; Kim, M. J. and others

    2000-04-01

    Facilities of the research and clinical treatments of neutron capture therapy using HANARO are developed, and they are ready to install. They are BNCT irradiation facility and prompt gamma neutron activatiion analysis facility. Since every horizontal neutron facility of HANARO is long and narrow tangential beam tube, it is analysed that sufficient epithermal neutrons for the BNCT cannot be obtained but sufficient thermal neutrons can be obtained by a filter composed of silicon and bismuth single crystals. Since the thermal neutron penetaration increases significantly when the crystals are cooled, a filter cooled by liquid nitrogen is developed. So as to avoid interference with the reactor operation, a water shutter is developed. The irradiation room is designed for the temporary surgical operation as well. Handling tools to remove activated beam port plug and to install water shutter and filter are developed. The basic structure of the irradiation room is already installed and most of other parts are ready to install. Since no free beam port is available for the prompt gamma neutron activation analysis, a method obtaining almost pure thermal neutrons by the vertical diffraction of extra beam for the polarized neutron spectrometer is developed. This method is confirmed by analysis and experiments to give high enough neutron beam. Equipment and devices are provided to install this facility

  7. Review of ion beam therapy: Present and Future

    International Nuclear Information System (INIS)

    Alonso, Jose R.

    2000-01-01

    First therapy efforts at the Bevalac using neon ions took place in the 70's and 80's. Promising results led to construction of HIMAC in Chiba Japan, and more recently to therapy trials at GSI. Both these facilities are now treating patients with carbon beams. Advances in both accelerator technology and beam delivery have taken place at these two centers. Plans are well along for new facilities in Europe and Japan

  8. External Beam Therapy (EBT)

    Science.gov (United States)

    ... type your comment or suggestion into the following text box: Comment: E-mail: Area code: Phone no: ... Colorectal Cancer Treatment Head and Neck Cancer Treatment Intensity-Modulated Radiation Therapy (IMRT) Brain ...

  9. Facilities for radiotherapy with ion beams status and worldwide developments

    CERN Document Server

    Wolf, B H

    1999-01-01

    Forty-five years after the first ion beam therapy in Berkeley around 25,000 cancer patients worldwide have been treated successfully. Ion accelerators, designed for nuclear research, delivered most of this treatment. The first hospital-based facility started operation in 1998 at Loma Linda California, the first for heavier ions at Chiba, Japan in 1994 and the first commercially delivered facilities started operation in 1998 at Kashiwa, Japan. In 2000, the Harvard Medical Centre, Boston, US, will commence operation and several new facilities are planned or under construction worldwide, although none in Australia. This paper will discuss the physical and biological advantages of ion beams over x-rays and electrons. In the treatment of cancer patients ion beam therapy is especially suited for localised tumours in radiation sensitive areas like skull or spine. Heavier ions are also effective in anoxic tumour cells (found around the normally oxygenated cell population). An additional advantage of the heavier carbo...

  10. Omega: A 24-beam UV irradiation facility

    International Nuclear Information System (INIS)

    Richardson, M.C.; Beich, W.; Delettrez, J.

    1985-01-01

    The authors report on the characterization and performance of the 24-beam Omega laser facility under full third harmonic (351-nm) upconversion. This system provides for the first time a multibeam laser facility for the illumination of spherical targets with UV laser light in symmetric irradiation conditions with energies in the kilojoule range. This facility is capable of providing sufficient irradiation uniformity to test concepts of direct drive laser fusion with UV-driven ablation targets. The results of initial studies of ablatively driven DT-fueled glass microballoon targets will be described. The 24-beam Omega Nd:phosphate glass facility is capable of providing at 1054 nm output powers in excess of 10 TW in short ( 10 4 full system shots to date) irradiation facility with beam synchronism of approx. =3 psec, beam placement accuracy on target of 10 μm, and interbeam energy variance of approx. =2%. From measured target plane intensity distributions, overall illumination uniformity with tangentially focused beams is estimated to be approx. =5%. In 1984, a symmetric set of six beams was upconverted to 351-nm radiation using the polarization-mismatch scheme developed by Craxton. Monolithic cells of 20-cm clear aperture containing both frequency and doubler and tripler type II KDP crystals in index-matching propylene carbonate liquid were incorporated to output of six of the Omega beams with a full set of UV beam diagnostics

  11. Proton-beam radiation therapy dosimetry standardization

    International Nuclear Information System (INIS)

    Gall, K.P.

    1995-01-01

    Beams of protons have been used for radiation therapy applications for over 40 years. In the last decade the number of facilities treating patients and the total number of patients being treated has begun go grow rapidly. Due to the limited and experimental nature of the early programs, dosimetry protocols tended to be locally defined. With the publication of the AAPM Task Group 20 report open-quotes Protocol for Dosimetry of Heavy Charged Particlesclose quotes and the open-quotes European Code of Practice for Proton-Beam Dosimetryclose quotes the practice of determining dose in proton-beam therapy was somewhat unified. The ICRU has also recently commissioned a report on recommendations for proton-beam dosimetry. There have been three main methods of determining proton dose; the Faraday cup technique, the ionization chamber technique, and the calorimeter technique. For practical reasons the ionization chamber technique has become the most widely used. However, due to large errors in basic parameters (e.g., W-value) is also has a large uncertainty for absolute dose. It has been proposed that the development of water calorimeter absorbed dose standards would reduce the uncertainty in absolute proton dose as well as the relative dose between megavoltage X-ray beams and proton beams. The advantages and disadvantages are discussed

  12. General considerations for neutron capture therapy at a reactor facility

    International Nuclear Information System (INIS)

    Binney, S.E.

    2001-01-01

    In addition to neutron beam intensity and quality, there are also a number of other significant criteria related to a nuclear reactor that contribute to a successful neutron capture therapy (NCT) facility. These criteria are classified into four main categories: Nuclear design factors, facility management and operations factors, facility resources, and non-technical factors. Important factors to consider are given for each of these categories. In addition to an adequate neutron beam intensity and quality, key requirements for a successful neutron capture therapy facility include necessary finances to construct or convert a facility for NCT, a capable medical staff to perform the NCT, and the administrative support for the facility. The absence of any one of these four factors seriously jeopardizes the overall probability of success of the facility. Thus nuclear reactor facility management considering becoming involved in neutron capture therapy, should it be proven clinically successful, should take all these factors into consideration. (author)

  13. The Continuous Electron Beam Accelerator Facility

    International Nuclear Information System (INIS)

    Grunder, H.A.; Bisognano, J.J.; Diamond, W.I.; Hartline, B.K.; Leemann, C.W.; Mougey, J.; Sundelin, R.M.; York, R.C.

    1987-01-01

    On February 13, 1987, construction started on the Continuous Electron Beam Accelerator Facility - a 4-GeV, 200-μA, continuous beam, electron accelerator facility designed for nuclear physics research. The machine has a racetrack configuration with two antiparallel, 500-MeV, superconducting linac segments connected by beam lines to allow four passes of recirculation. The accelerating structure consists of 1500-MHz, five-cell niobium cavities developed at Cornell University. A liquid helium cryogenic system cools the cavities to an operating temperature of 2 K. Beam extraction after any three of the four passes allows simultaneous delivery of up to three beams of independently variable currents and different, but correlated, energies to the three experimental areas. Beam breakup thresholds exceed the design current by nearly two orders of magnitude. Project completion and the start of physics operations are scheduled for 1993. The total estimated cost is $255 million

  14. Neutron beams for therapy

    International Nuclear Information System (INIS)

    Kuplenikov, Eh.L.; Dovbnya, A.N.; Telegin, Yu.N.; Tsymbal, V.A.; Kandybej, S.S.

    2011-01-01

    It was given the analysis and generalization of the study results carried out during some decades in many world countries on application of thermal, epithermal and fast neutrons for neutron, gamma-neutron and neutron-capture therapy. The main attention is focused on the practical application possibility of the accumulated experience for the base creation for medical research and the cancer patients effective treatment.

  15. Radioactive ion beam facilities in Europe

    International Nuclear Information System (INIS)

    Blumenfeld, Y.

    2008-01-01

    The past two decades have seen extraordinarily rapid development of radioactive beam physics throughout the world and in particular in Europe. The important scientific advances have stemmed from a large number of facilities. Previously existing stable beam machines have been adapted to produce rare isotope beams and dedicated facilities have come on-line. This talk gives an overview of the present European installations highlighting their complementary nature. The European roadmap calls for the construction of two next generation facilities: FAIR making use of projectile fragmentation and EURISOL based on the ISOL technique. The future FAIR facility will be described and the path towards EURISOL presented in the light of the construction of 'intermediate' generation facilities SPIRAL2, HIE ISOLDE and SPES and results from the ongoing EURISOL Design Study.

  16. World new facilities for radioactive isotope beams

    International Nuclear Information System (INIS)

    Motobayashi, T.

    2014-01-01

    The use of unstable nuclei in the form of energetic beams for nuclear physics studies is now entering into a new era. 'New-generation' facilities are either in operation, under construction or being planned. They are designed to provide radioactive isotope (RI) beams with very high intensities over a wide range of nuclides. These facilities are expected to provide opportunities to study nuclear structure, astrophysical nuclear processes and nuclear matter with large proton-neutron imbalance in grate detail. This article reports on the current status of such new-generation RI-beam facilities around the world. In order to cover different energy domains and to meet various scientific demands, the designs of RI-beam facilities are of a wide variety. For example, RIBF in Japan, FAIR in Germany and FRIB in US are based on the fragmentation scheme for beams with energies of a few hundred MeV/nucleon to GeV/nucleon, whereas Spiral2 in France, SPES in Italy, HIE-ISOLDE in Switzerland/France, and the future facility EURISOL in Europe are based on the ISOL method, and aim at providing lower-energy RI beams. There are a many other projects including upgrades of existing facilities in the three continents, America, Asia and Europe

  17. Radioactive ion beam facilities at INFN LNS

    International Nuclear Information System (INIS)

    Rifuggiato, D; Calabretta, L; Celona, L; Chines, F; Cosentino, L; Cuttone, G; Finocchiaro, P; Pappalardo, A; Re, M; Rovelli, A

    2011-01-01

    Radioactive ion beams are produced at INFN- Laboratori Nazionali del Sud (LNS) by means of the two operating accelerators, the Tandem and the Superconducting Cyclotron (CS), originally designed to accelerate stable beams. Both the ISOL (Isotope Separation On Line) and the IFF (In-Flight Fragmentation) methods are exploited to produce RIBs in two different ways at different energies: in the first case, the Cyclotron is the primary accelerator and the Tandem accelerates the secondary beams, while in the second case radioactive fragments are produced by the Cyclotron beam in a thin target with energies comparable to the primary beam energy. The ISOL facility is named EXCYT (Exotics at the Cyclotron and Tandem) and was commissioned in 2006, when the first radioactive beam ( 8 Li) has been produced. The IFF installation is named FRIBs (in Flight Radioactive Ion Beams), and it has started to produce radioactive beams in 2001, placing a thin target in the extraction beam line of the Cyclotron. The development of both facilities to produce and accelerate radioactive ion beams at LNS, is briefly described, with some details on the future prospects that are presently under consideration or realization.

  18. The ISOLDE Facility: Radioactive beams at CERN

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    The Isope Separation On-Line (ISOL) technique evolved from chemical techniques used to separate radioactive isotopes off-line from irradiated "targets". The ISOL targets of today, used at e.g. ISOLDE, can be of many different types and in different phases but the isotopes are always delivered at very low energies making the technique ideal for study of ground state properties and collections for other applications such as solid state physics and medical physics. The possibility of accelerating these low energy beams for nuclear structure studies, and in the long term future for neutrino physics, is now being explored at first generation radioactive beam facilities. The upgrade towards HIE-ISOLDE aim to consolidate ISOLDE's position as a world leading radioactive nuclear beam facility and it will be a pre-cursor to a future all European ISOL facility, EURISOL, with order of magnitudes higher radioactive beam intensities and energies. Prerequisite knowledge and references: None

  19. A neutron beam facility at Spiral-2

    Energy Technology Data Exchange (ETDEWEB)

    Ledoux, X.; Bauge, E.; Belier, G.; Ethvignot, T.; Taieb, J.; Varignon, C. [CEA Bruyeres-le-Chatel, DIF, 91 (France); Andriamonje, S.; Dore, D.; Dupont, E.; Gunsing, F.; Ridikas, D.; Takibayev, A. [CEA Saclay, DSM/IRFU/SPhN, 91 - Gif-sur-Yvette (France); Blideanu, V. [CEA Saclay, DSM/IRFU/Senac, 91 - Gif-sur-Yvette (France); Aiche, M.; Barreau, G.; Czajkowski, S.; Jurado, B. [Centre d' Etudes Nucleaires de Bordeaux Gradignan, 33 (France); Ban, G.; Lecolley, F.R.; Lecolley, J.F.; Lecouey, J.L.; Marie, N.; Steckmeyer, J.C. [LPC, 14 - Caen (France); Dessagne, P.; Kerveno, M.; Rudolf, G. [IPHC, 57 - Strasbourg (France); Bem, P.; Mrazek, J.; Novak, J. [NPI, Rez (Czech Republic); Blomgren, J.; Pomp, S. [Uppsala Univ., Dept. of Physics and Astronomy (Sweden); Fischer, U.; Herber, S.; Simakov, S.P. [FZK, Karlsruhe (Germany); Jacquot, B.; Rejmund, F. [GANIL, 14 - Caen (France); Avrigeanu, M.; Avrigeanu, V.; Borcea, C.; Negoita, F.; Petrascu, M. [NIPNE, Bucharest (Romania); Oberstedt, S.; Plompen, A.J.M. [JRC/IRMM, Geel (Belgium); Shcherbakov, O. [PNPI, Gatchina (Russian Federation); Fallot, M. [Subatech, 44 - Nantes (France); Smith, A.G.; Tsekhanovich, I. [Manchester Univ., Dept. of Physics and Astronomy (United Kingdom); Serot, O.; Sublet, J.C. [CEA Cadarache, DEN, 13 - Saint-Paul-lez-Durance (France); Perrot, L.; Tassan-Got, L. [IPNO, 91 - Orsay (France); Caillaud, T.; Giot, L.; Landoas, O.; Ramillon, J.M.; Rosse, B.; Thfoin, I. [CIMAP, 14 - Caen (France); Balanzat, E.; Bouffard, S.; Guillous, S.; Oberstedt, A. [Orebro Univ. (Sweden)

    2009-07-01

    The future Spiral-2 facility, dedicated to the production of intense radioactive ion beams, is based on a high-power superconducting driver Linac, delivering high-intensity deuteron, proton and heavy ion beams. These beams are particularly well suited to the production of neutrons in the 100 keV- 40 MeV energy range, a facility called 'Neutrons for Science' (NFS) will be built in the LINAG Experimental Area (LEA). NFS, operational in 2012, will be composed of a pulsed neutron beam for in-flight measurements and irradiation stations for activation measurements and material studies. Thick C and Be converters and a deuteron beam will produce an intense continuous neutron spectrum, while a thin {sup 7}Li target and a proton beam allow to generate quasi-mono-energetic neutrons. In the present work we show how the primary ion beam characteristics (energy, time resolution and intensity) are adequate to create a neutron time-of-flight facility delivering intense neutron fluxes in the 100 keV-40 MeV energy range. Irradiation stations for neutron, proton and deuteron reactions will also allow to perform cross-section measurements by means of the activation technique. Light-ion beams will be used to study radiation damage effects on materials for the nuclear industry. (authors)

  20. Fan-beam intensity modulated proton therapy.

    Science.gov (United States)

    Hill, Patrick; Westerly, David; Mackie, Thomas

    2013-11-01

    This paper presents a concept for a proton therapy system capable of delivering intensity modulated proton therapy using a fan beam of protons. This system would allow present and future gantry-based facilities to deliver state-of-the-art proton therapy with the greater normal tissue sparing made possible by intensity modulation techniques. A method for producing a divergent fan beam of protons using a pair of electromagnetic quadrupoles is described and particle transport through the quadrupole doublet is simulated using a commercially available software package. To manipulate the fan beam of protons, a modulation device is developed. This modulator inserts or retracts acrylic leaves of varying thickness from subsections of the fan beam. Each subsection, or beam channel, creates what effectively becomes a beam spot within the fan area. Each channel is able to provide 0-255 mm of range shift for its associated beam spot, or stop the beam and act as an intensity modulator. Results of particle transport simulations through the quadrupole system are incorporated into the MCNPX Monte Carlo transport code along with a model of the range and intensity modulation device. Several design parameters were investigated and optimized, culminating in the ability to create topotherapy treatment plans using distal-edge tracking on both phantom and patient datasets. Beam transport calculations show that a pair of electromagnetic quadrupoles can be used to create a divergent fan beam of 200 MeV protons over a distance of 2.1 m. The quadrupole lengths were 30 and 48 cm, respectively, with transverse field gradients less than 20 T/m, which is within the range of water-cooled magnets for the quadrupole radii used. MCNPX simulations of topotherapy treatment plans suggest that, when using the distal edge tracking delivery method, many delivery angles are more important than insisting on narrow beam channel widths in order to obtain conformal target coverage. Overall, the sharp distal

  1. A reviewed technique for total body electron therapy using a Varian Clinac 2100C/D high dose rate treatment beam facility

    International Nuclear Information System (INIS)

    Oliver, L.D.; Xuereb, E.M.A.; Last, V.; Hunt, P.B.; Wilfert, A.

    1996-01-01

    Our (Royal North Shore Hospital) most recent linear accelerator acquisition is a Varian Clinac 2100C/D which has a high dose rate (approximately 25Gy per minute at 1 metre) total body electron option. We investigated the physical characteristics of the electron beam to develop a suitable method of treatment for total body electron therapy. The useful electron beam width is defined as 80cm above and below the reference height. Measurements of the electron dose received from the two angled electron beams showed a critical dependence on the gantry angles. The treatment protocol uses ten different patient angles, fractionated into directly opposing fields and treated seuqentially each day. A full cycle of treatment is completed in five days. (author)

  2. The clinical case for proton beam therapy

    Directory of Open Access Journals (Sweden)

    Foote Robert L

    2012-10-01

    Full Text Available Abstract Over the past 20 years, several proton beam treatment programs have been implemented throughout the United States. Increasingly, the number of new programs under development is growing. Proton beam therapy has the potential for improving tumor control and survival through dose escalation. It also has potential for reducing harm to normal organs through dose reduction. However, proton beam therapy is more costly than conventional x-ray therapy. This increased cost may be offset by improved function, improved quality of life, and reduced costs related to treating the late effects of therapy. Clinical research opportunities are abundant to determine which patients will gain the most benefit from proton beam therapy. We review the clinical case for proton beam therapy. Summary sentence Proton beam therapy is a technically advanced and promising form of radiation therapy.

  3. The clinical case for proton beam therapy

    International Nuclear Information System (INIS)

    Foote, Robert L; Haddock, Michael G; Yan, Elizabeth; Laack, Nadia N; Arndt, Carola A S

    2012-01-01

    Over the past 20 years, several proton beam treatment programs have been implemented throughout the United States. Increasingly, the number of new programs under development is growing. Proton beam therapy has the potential for improving tumor control and survival through dose escalation. It also has potential for reducing harm to normal organs through dose reduction. However, proton beam therapy is more costly than conventional x-ray therapy. This increased cost may be offset by improved function, improved quality of life, and reduced costs related to treating the late effects of therapy. Clinical research opportunities are abundant to determine which patients will gain the most benefit from proton beam therapy. We review the clinical case for proton beam therapy. Proton beam therapy is a technically advanced and promising form of radiation therapy

  4. Poster: The EURISOL Beta-beam facility

    CERN Document Server

    The beta-beam concept for the generation of an electron (anti-)neutrino beam was proposed by Piero Zucchelli (CERN) in 2002. A first study of the possibility of using the existing CERN machines for the acceleration for radioactive ions to a relativistic gamma of roughly 100, for later storage in a new decay ring of approximately the size of SPS, was made in 2002. The results from this very first short study were very encouraging.In 2004 it was decided to incorporate a design study for the beta-beam within the EURISOL DS proposal. EURISOL is a project name for a next-generation radioactive beam facility based on the ISOL method for the production of intense radioactive beams for nuclear physics, astrophysics and other applications. The proposal was accepted with the beta-beam task as an integral part. The design study officially started 1 February 2005 and will run for 4 years resulting in a conceptual design report for a beta-beam facility.

  5. Radiation therapy apparatus having retractable beam stopper

    International Nuclear Information System (INIS)

    Coad, G.L.

    1983-01-01

    This invention relates to a radiation therapy apparatus which utilized a linear translation mechanism for positioning a beam stopper. An apparatus is described wherein the beam stopper is pivotally attached to the therapy machine with an associated drive motor in such a way that the beam stopper retracts linearly

  6. Proton-proton colliding beam facility ISABELLE

    International Nuclear Information System (INIS)

    Hahn, H.

    1980-01-01

    This paper attempts to present the status of the ISABELLE construction project, which has the objective of building a 400 + 400 GeV proton colliding beam facility. The major technical features of the superconducting accelerators with their projected performance are described. Progress made so far, difficulties encountered, and the program until completion in 1986 is briefly reviewed

  7. Proton beam therapy control system

    Science.gov (United States)

    Baumann, Michael A [Riverside, CA; Beloussov, Alexandre V [Bernardino, CA; Bakir, Julide [Alta Loma, CA; Armon, Deganit [Redlands, CA; Olsen, Howard B [Colton, CA; Salem, Dana [Riverside, CA

    2008-07-08

    A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

  8. A radioactive ion beam facility using photofission

    CERN Document Server

    Diamond, W T

    1999-01-01

    Use of a high-power electron linac as the driver accelerator for a Radioactive Ion Beam (RIB) facility is proposed. An electron beam of 30 MeV and 100 kW can produce nearly 5x10 sup 1 sup 3 fissions/s from an optimized sup 2 sup 3 sup 5 U target and about 60% of this from a natural uranium target. An electron beam can be readily transmitted through a thin window at the exit of the accelerator vacuum system and transported a short distance through air to a water-cooled Bremsstrahlung-production target. The Bremsstrahlung radiation can, in turn, be transported through air to the isotope-production target. This separates the accelerator vacuum system, the Bremsstrahlung target and the isotope-production target, reducing remote handling problems. The electron beam can be scanned over a large target area to reduce the power density on both the Bremsstrahlung and isotope-production targets. These features address one of the most pressing technological challenges of a high-power RIB facility, namely the production o...

  9. Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

    CERN Document Server

    Shornikov, A.

    2016-01-01

    In this work we analyze how advanced Electron Beam Ion Sources (EBIS) can facilitate the progress of carbon therapy facilities. We will demonstrate that advanced ion sources enable operation of 2-nd generation ion beam therapy (IBT) accelerators. These new accelerator concepts with designs dedicated to IBT provide beams better suited for therapy and, are more cost efficient than contemporary IBT facilities. We will give a sort overview of the existing new IBT concepts and focus on those where ion source technology is the limiting factor. We will analyse whether this limitation can be overcome in the near future thanks to ongoing EBIS development.

  10. External Beam Radiation Therapy for Cancer

    Science.gov (United States)

    External beam radiation therapy is used to treat many types of cancer. it is a local treatment, where a machine aims radiation at your cancer. Learn more about different types of external beam radiation therapy, and what to expect if you're receiving treatment.

  11. ORNL 150 keV neutral beam test facility

    International Nuclear Information System (INIS)

    Gardner, W.L.; Kim, J.; Menon, M.M.; Schilling, G.

    1977-01-01

    The 150 keV neutral beam test facility provides for the testing and development of neutral beam injectors and beam systems of the class that will be needed for the Tokamak Fusion Test Reactor (TFTR) and The Next Step (TNS). The test facility can simulate a complete beam line injection system and can provide a wide range of experimental operating conditions. Herein is offered a general description of the facility's capabilities and a discussion of present system performance

  12. Electron beam facility for divertor target experiments

    International Nuclear Information System (INIS)

    Anisimov, A.; Gagen-Torn, V.; Giniyatulin, R.N.

    1994-01-01

    To test different concepts of divertor targets and bumpers an electron beam facility was assembled in Efremov Institute. It consists of a vacuum chamber (3m 3 ), vacuum pump, electron beam gun, manipulator to place and remove the samples, water loop and liquid metal loop. The following diagnostics of mock-ups is stipulated: (1) temperature distribution on the mock-up working surface (scanning pyrometer and infra-red imager); (2) temperature distribution over mocked-up thickness in 3 typical cross-sections (thermo-couples); (3) cracking dynamics during thermal cycling (acoustic-emission method), (4) defects in the mock-up before and after tests (ultra-sonic diagnostics, electron and optical microscopes). Carbon-based and beryllium mock-ups are made for experimental feasibility study of water and liquid-metal-cooled divertor/bumper concepts

  13. Australian proton therapy facilities - status report

    International Nuclear Information System (INIS)

    Bleasel, S.; Jackson, M.

    2000-01-01

    Full text: Radiotherapy plays an important role in the treatment of cancer; both in the curative treatment of localised disease and in alleviating symptoms in more advanced disease. Radiotherapy is usually given with megavoltage X-rays which give good penetration at depth and a lower dose on the skin. The aim is to give a high dose to the tumour while keeping the dose to normal tissues as low as possible. While X-rays continue beyond the target volume, protons and other charged particles have a finite range in tissue and this allows the high dose region to closely conform to the tumour, thereby giving the best chance of tumour control with minimum side effects. This is particularly important for small tumours adjacent to critical normal structures. The unmodified Bragg peak is too narrow to be useful but can be spread out to cover the tumour. Protons of energy 70 - 250 MeV are required to achieve the optimal depth in the body. Protons have been used for cancer treatment since 1954 but most of these treatments have been given in physics-based facilities which do not provide an ideal environment for the patient and may have only limited beam time available. A dedicated, hospital based facility was built at Loma Linda in California in 1991 and has now treated over 5,000 patients. Several other centres are being built in the USA, Japan and Europe and one is now being considered for Australia. Early 1998 Hitachi Australia Ltd. was asked to research the possibility of building a facility in Australia to serve Oceania. Two major hospitals showed interest, Royal Brisbane Hospital and Royal Prince Alfred Hospital. Both hospitals are undergoing redevelopment and have space for a building 3 stories high with a foot-print of approximately 50 m x 50 m. What is proposed for Australia is a principally clinical research facility with a dedicated area for physics research. A Steering Committee will be established to develop a document for presentation to Government. The facility

  14. A beam monitor using silicon pixel sensors for hadron therapy

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhen, E-mail: zwang@mails.ccnu.edu.cn; Zou, Shuguang; Fan, Yan; Liu, Jun; Sun, Xiangming, E-mail: sphy2007@126.com; Wang, Dong; Kang, Huili; Sun, Daming; Yang, Ping; Pei, Hua; Huang, Guangming; Xu, Nu; Gao, Chaosong; Xiao, Le

    2017-03-21

    We report the design and test results of a beam monitor developed for online monitoring in hadron therapy. The beam monitor uses eight silicon pixel sensors, Topmetal-II{sup -}, as the anode array. Topmetal-II{sup -} is a charge sensor designed in a CMOS 0.35 µm technology. Each Topmetal-II{sup -} sensor has 72×72 pixels and the pixel size is 83×83 µm{sup 2}. In our design, the beam passes through the beam monitor without hitting the electrodes, making the beam monitor especially suitable for monitoring heavy ion beams. This design also reduces radiation damage to the beam monitor itself. The beam monitor is tested with a carbon ion beam at the Heavy Ion Research Facility in Lanzhou (HIRFL). Results indicate that the beam monitor can measure position, incidence angle and intensity of the beam with a position resolution better than 20 µm, angular resolution about 0.5° and intensity statistical accuracy better than 2%.

  15. Beam monitoring in radiotherapy and hadron-therapy

    International Nuclear Information System (INIS)

    Fontbonne, J.M.

    2012-01-01

    Radiotherapy techniques have evolved over the past twenty years. For photon beams, the development of tools such as multi leaf collimators, machines such as Cyberknife or tomo-therapy, have improved the conformation of treatments to the tumor volume and lowered maximum dose to healthy tissue. In another register, the use of proton-therapy is expanding in all countries and the development of carbon ions beams for hadron-therapy is also increasing. If techniques improve, the control requirements for the monitoring of the dose administered to patients are always the same. This document presents, first, the ins and outs of the different techniques of external beam radiotherapy: photon treatments, protons and hadrons. Starting from the basis of clinical requirements, it sets the variables to be measured in order to ensure the quality of treatment for the different considered modalities. It then describes some implementations, based on precise and rigorous specifications, for the monitoring and measurement of beams delivered by external beam radiotherapy equipments. Two instrumental techniques are particularly highlighted, plastic scintillators dosimetry for the control of megavoltage photon beams and ionization chamber dosimetry applied to proton-therapy or radiobiology experiments conducted at the GANIL facility. Analyzes and perspectives, based on the recent developments of treatment techniques, are delivered in conclusion and can serve as guide for future instrumental developments. (author)

  16. Improvements of present radioactive beam facilities and new projects

    International Nuclear Information System (INIS)

    Mueller, A.C.

    1995-01-01

    A short overview is given over scheduled improvements of present radioactive beam facilities and of new projects. In order to put these into a coherent context the paper starts with a general section about the making of radioactive beams. (author)

  17. Health physics considerations at a neutron therapy facility cyclotron

    International Nuclear Information System (INIS)

    Kleck, J.H.; Krueger, D.J.; Mc Laughlin, J.E.; Smathers, J.B.

    1987-01-01

    The U.C.L.A. Neutron Therapy Facility (NTF) is one of four such facilities in the United States currently involved in NCI sponsored trials of neutron therapy and reflects the present interest in the use of high energy neutron beams for treating certain types of human cancers. The NTF houses a CP-45 negative ion cyclotron which accelerates a 46 MeV proton beam for production of neutrons from a beryllium target. In addition to patient treatment, the NTF is involved in the production of positron emitting radioisotopes for diagnostic use in Positron Emission Tomography (PET). The activation of therapy treatment collimators, positron and neutron target systems, and a high and rapidly varying external radiation environment in a clinical setting have contributed to the need for a comprehensive radiation control program in which patient care is balanced with the maintenance of occupational exposures to ALARA levels

  18. Heavy ion facility for radiation therapy

    International Nuclear Information System (INIS)

    Leemann, C.; Alonso, J.; Clark, D.; Grunder, H.; Hoyer, E.; Lou, K.; Staples, J.; Voelker, F.

    1977-03-01

    The accelerator requirements of particle radiation therapy are reviewed and a preliminary design of a heavy ion synchrotron for hospital installation is presented. Beam delivery systems and multi-treatment room arrangements are outlined

  19. Design of an irradiation facility with thermal, epithermal and fast neutron beams

    International Nuclear Information System (INIS)

    Pfister, G.; Bernnat, W.; Seidel, R.; Schatz, A.K.; Wagner, F.M.; Waschkowski, W.; Schraube, H.

    1992-01-01

    The main features of a neutron irradiation facility to be installed at the planned research reactor FRM-II are presented. In addition to the operational possibilities of the existing facility at the reactor FRM-I, the new facility will produce quasi-monoenergetic neutron fields and a neutron beam in the keV region whose spectrum can be modified by application of suitable filters and scatterers. For this beam, which is well suited for boron capture therapy, calculated boron reaction rates inside a phantom and an experimental verification of the calculations at the existing facility are presented. (orig.) [de

  20. TFTR neutral-beam test facility

    International Nuclear Information System (INIS)

    Turitzin, N.M.; Newman, R.A.

    1981-11-01

    TFTR Neutral Beam System will have thirteen discharge ion sources, each with its own power supply. Twelve of these will be utilized for supplemental heating of the TFTR tokamak plasma, while the thirteenth will be dedicated to an off-machine test chamber for source development and/or conditioning. A test installation for one source was set up using prototype equipment to discover and correct possible deficiencies, and to properly coordinate the equipment. This test facility represents the first opportunity for assembling an integrated system of hardware supplied by diverse vendors, each of whom designed and built his equipment to performance specifications. For the installation and coordination of the different portions of the total system, particular attention was given to personnel safety and safe equipment operation. This paper discusses various system components, their characteristics, interconnection and control. Results of the recently initiated test phase will be reported at a later date

  1. The continuous electron beam accelerator facility

    International Nuclear Information System (INIS)

    Grunder, H.A.

    1989-01-01

    Tunnel construction and accelerator component development, assembly, and testing are under way at the Continuous Electron Beam Accelerator Facility. CEBAF's 4-GeV, 200-μA superconducting recirculating accelerator will provide cw beam to simultaneous experiments in three end stations for studies of the nuclear many-body system, its quark substructure, and the strong and electroweak interactions governing this form of matter. Prototype accelerating cavities, assembled in cryostats and tested on site, continue to exceed performance specifications. An on-site liquid helium capability supports cryostat development and cavity testing. Major elements of the accelerator instrumentation and control hardware and software are in use in cryogenics, rf, and injector tests. Prototype rf systems have been operated and prototype klystrons have been ordered. The initial, 100-keV, room-temperature region of the 45-MeV injector is operational and meets specifications. CEBAF's end stations have been conceptually designed; experimental equipment conceptual designs will be completed in 1989. 2 refs., 5 figs., 2 tabs

  2. Development of the Holifield Radioactive Ion Beam Facility

    International Nuclear Information System (INIS)

    Tatum, B.A.

    1997-01-01

    The Holifield Radioactive Ion Beam Facility (HRIBF) construction project has been completed and the first radioactive ion beam has been successfully accelerated. The project, which began in 1992, has involved numerous facility modifications. The Oak Ridge Isochronous Cyclotron has been converted from an energy booster for heavy ion beams to a light ion accelerator with internal ion source. A target-ion source and mass analysis system have been commissioned as key components of the facility's radioactive ion beam injector to the 25MV tandem electrostatic accelerator. Beam transport lines have been completed, and new diagnostics for very low intensity beams have been developed. Work continues on a unified control system. Development of research quality radioactive beams for the nuclear structure and nuclear astrophysics communities continues. This paper details facility development to date

  3. Wire Scanner Beam Profile Measurements: LANSCE Facility Beam Development

    International Nuclear Information System (INIS)

    Gilpatrick, John D.; Batygin, Yuri K.; Gonzales, Fermin; Gruchalla, Michael E.; Kutac, Vincent G.; Martinez, Derwin; Sedillo, James Daniel; Pillai, Chandra; Rodriguez Esparza, Sergio; Smith, Brian G.

    2012-01-01

    The Los Alamos Neutron Science Center (LANSCE) is replacing Wire Scanner (WS) beam profile measurement systems. Three beam development tests have taken place to test the new wire scanners under beam conditions. These beam development tests have integrated the WS actuator, cable plant, electronics processors and associated software and have used H - beams of different beam energy and current conditions. In addition, the WS measurement-system beam tests verified actuator control systems for minimum profile bin repeatability and speed, checked for actuator backlash and positional stability, tested the replacement of simple broadband potentiometers with narrow band resolvers, and tested resolver use with National Instruments Compact Reconfigurable Input and Output (cRIO) Virtual Instrumentation. These beam tests also have verified how trans-impedance amplifiers react with various types of beam line background noise and how noise currents were not generated. This paper will describe these beam development tests and show some resulting data.

  4. Wire Scanner Beam Profile Measurements: LANSCE Facility Beam Development

    Energy Technology Data Exchange (ETDEWEB)

    Gilpatrick, John D. [Los Alamos National Laboratory; Batygin, Yuri K. [Los Alamos National Laboratory; Gonzales, Fermin [Los Alamos National Laboratory; Gruchalla, Michael E. [Los Alamos National Laboratory; Kutac, Vincent G. [Los Alamos National Laboratory; Martinez, Derwin [Los Alamos National Laboratory; Sedillo, James Daniel [Los Alamos National Laboratory; Pillai, Chandra [Los Alamos National Laboratory; Rodriguez Esparza, Sergio [Los Alamos National Laboratory; Smith, Brian G. [Los Alamos National Laboratory

    2012-05-15

    The Los Alamos Neutron Science Center (LANSCE) is replacing Wire Scanner (WS) beam profile measurement systems. Three beam development tests have taken place to test the new wire scanners under beam conditions. These beam development tests have integrated the WS actuator, cable plant, electronics processors and associated software and have used H{sup -} beams of different beam energy and current conditions. In addition, the WS measurement-system beam tests verified actuator control systems for minimum profile bin repeatability and speed, checked for actuator backlash and positional stability, tested the replacement of simple broadband potentiometers with narrow band resolvers, and tested resolver use with National Instruments Compact Reconfigurable Input and Output (cRIO) Virtual Instrumentation. These beam tests also have verified how trans-impedance amplifiers react with various types of beam line background noise and how noise currents were not generated. This paper will describe these beam development tests and show some resulting data.

  5. A pencil beam algorithm for helium ion beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Fuchs, Hermann; Stroebele, Julia; Schreiner, Thomas; Hirtl, Albert; Georg, Dietmar [Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna, 1090 Vienna (Austria); Department of Radiation Oncology, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria) and Comprehensive Cancer Center, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria); Department of Radiation Oncology, Medical University of Vienna/AKH Vienna (Austria) and Comprehensive Cancer Center, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria); PEG MedAustron, 2700 Wiener Neustadt (Austria); Department of Nuclear Medicine, Medical University of Vienna, 1090 Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna, 1090 Vienna (Austria); Department of Radiation Oncology, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria) and Comprehensive Cancer Center, Medical University of Vienna/AKH Vienna, 1090 Vienna (Austria)

    2012-11-15

    Purpose: To develop a flexible pencil beam algorithm for helium ion beam therapy. Dose distributions were calculated using the newly developed pencil beam algorithm and validated using Monte Carlo (MC) methods. Methods: The algorithm was based on the established theory of fluence weighted elemental pencil beam (PB) kernels. Using a new real-time splitting approach, a minimization routine selects the optimal shape for each sub-beam. Dose depositions along the beam path were determined using a look-up table (LUT). Data for LUT generation were derived from MC simulations in water using GATE 6.1. For materials other than water, dose depositions were calculated by the algorithm using water-equivalent depth scaling. Lateral beam spreading caused by multiple scattering has been accounted for by implementing a non-local scattering formula developed by Gottschalk. A new nuclear correction was modelled using a Voigt function and implemented by a LUT approach. Validation simulations have been performed using a phantom filled with homogeneous materials or heterogeneous slabs of up to 3 cm. The beams were incident perpendicular to the phantoms surface with initial particle energies ranging from 50 to 250 MeV/A with a total number of 10{sup 7} ions per beam. For comparison a special evaluation software was developed calculating the gamma indices for dose distributions. Results: In homogeneous phantoms, maximum range deviations between PB and MC of less than 1.1% and differences in the width of the distal energy falloff of the Bragg-Peak from 80% to 20% of less than 0.1 mm were found. Heterogeneous phantoms using layered slabs satisfied a {gamma}-index criterion of 2%/2mm of the local value except for some single voxels. For more complex phantoms using laterally arranged bone-air slabs, the {gamma}-index criterion was exceeded in some areas giving a maximum {gamma}-index of 1.75 and 4.9% of the voxels showed {gamma}-index values larger than one. The calculation precision of the

  6. Synchrotron light beam and a synchrotron light experiment facility

    International Nuclear Information System (INIS)

    Ando, Masami

    1980-01-01

    In the National Laboratory for High Energy Physics, about two years ago, the requirements of synchrotron light beam in respective measuring instruments were discussed. Then, also the arrangement (lattice) of a storage ring, the nature of synchrotron light beam, a synchrotron light experiment facility and the arrangement of the beam lines were studied. During the period of two years since then, due to the changes in the circumstances, the design of the lattice was altered. Accordingly, the arrangement of the beam lines and of measuring instruments were largely changed. At this point, the results of discussions in various meetings are described, though they may still be subject to future changes, with due consideration to beam, environment and beam lines required for the design of the measuring instruments: (1) storage ring and synchrotron light beam, (2) requirements on small beam size and beam stability, (3) a synchrotron light experiment facility. (J.P.N.)

  7. Beam profile monitors for a tagged photon beam facility

    International Nuclear Information System (INIS)

    Arends, J.; Breuer, M.; Dahmen, H.D.; Detemple, P.; Schneider, W.; Urban, D.; Zucht, B.

    1991-01-01

    A beam profile monitor for electron and photon beams is described, which operates at the low intensities encountered in a tagged bremsstrahlung beam environment, typically 10 10 electrons/s and 10 7 photons/s. The method is based on a wire scanner and utilizes the presence of a tagging spectrometer. The accuracy of the measurements can be tuned in a wide range to meet the requirements set by the actual beam parameters. Examples of measured electron and photon beam profiles at the tagged photon beam of the PHOENICS experiment at the electron stretcher ring ELSA in Bonn are given. (orig.)

  8. Fan beam intensity modulated proton therapy

    Science.gov (United States)

    Hill, Patrick M.

    A fan beam proton therapy is developed which delivers intensity modulated proton therapy using distal edge tracking. The system may be retrofit onto existing proton therapy gantries without alterations to infrastructure in order to improve treatments through intensity modulation. A novel range and intensity modulation system is designed using acrylic leaves that are inserted or retracted from subsections of the fan beam. Leaf thicknesses are chosen in a base-2 system and motivated in a binary manner. Dose spots from individual beam channels range between 1 and 5 cm. Integrated collimators attempting to limit crosstalk among beam channels are investigated, but found to be inferior to uncollimated beam channel modulators. A treatment planning system performing data manipulation in MATLAB and dose calculation in MCNPX is developed. Beamlet dose is calculated on patient CT data and a fan beam source is manually defined to produce accurate results. An energy deposition tally follows the CT grid, allowing straightforward registration of dose and image data. Simulations of beam channels assume that a beam channel either delivers dose to a distal edge spot or is intensity modulated. A final calculation is performed separately to determine the deliverable dose accounting for all sources of scatter. Treatment plans investigate the effects that varying system parameters have on dose distributions. Beam channel apertures may be as large as 20 mm because the sharp distal falloff characteristic of proton dose provides sufficient intensity modulation to meet dose objectives, even in the presence of coarse lateral resolution. Dose conformity suffers only when treatments are delivered from less than 10 angles. Jaw widths of 1--2 cm produce comparable dose distributions, but a jaw width of 4 cm produces unacceptable target coverage when maintaining critical structure avoidance. Treatment time for a prostate delivery is estimated to be on the order of 10 minutes. Neutron production

  9. Review of electron beam therapy physics

    International Nuclear Information System (INIS)

    Hogstrom, Kenneth R; Almond, Peter R

    2006-01-01

    For over 50 years, electron beams have been an important modality for providing an accurate dose of radiation to superficial cancers and disease and for limiting the dose to underlying normal tissues and structures. This review looks at many of the important contributions of physics and dosimetry to the development and utilization of electron beam therapy, including electron treatment machines, dose specification and calibration, dose measurement, electron transport calculations, treatment and treatment-planning tools, and clinical utilization, including special procedures. Also, future changes in the practice of electron therapy resulting from challenges to its utilization and from potential future technology are discussed. (review)

  10. Dose reporting in ion beam therapy. Proceedings of a meeting

    International Nuclear Information System (INIS)

    2007-06-01

    Following the pioneering work in Berkeley, USA, ion beam therapy for cancer treatment is at present offered in Chiba and Hyogo in Japan, and Darmstadt in Germany. Other facilities are coming close to completion or are at various stages of planning in Europe and Japan. In all these facilities, carbon ions have been selected as the ions of choice, at least in the first phase. Taking into account this fast development, the complicated technical and radiobiological research issues involved, and the hope it raises for some types of cancer patients, the IAEA and the International Commission on Radiation Units and measurements (ICRU) jointly sponsored a technical meeting held in Vienna, 23-24 June 2004. That first meeting was orientated mainly towards radiobiology: the relative biological effectiveness (RBE) of carbon ions versus photons, and related issues. One of the main differences between ion beam therapy and other modern radiotherapy techniques (such as proton beam therapy or intensity modulated radiation therapy) is related to radiobiology and in particular the increased RBE of carbon ions compared to both protons and photons (i.e., high linear energy transfer (LET) versus low LET radiation). Another important issue for international agencies and commissions, such as the IAEA and the ICRU, is a worldwide agreement and harmonisation for reporting the treatments. In order to evaluate the merits of ion beam therapy, it is essential that the treatments be reported in a similar/comparable way in all centres so that the clinical reports and protocols can be understood and interpreted without ambiguity by the radiation therapy community in general. For the last few decades, the ICRU has published several reports containing recommendations on how to report external photon beam or electron beam therapy, and brachytherapy. A report on proton beam therapy, jointly prepared by the ICRU and the IAEA, is now completed and is being published in the ICRU series. In line with this

  11. BEAM LINE DESIGN FOR THE CERN HIRADMAT TEST FACILITY

    CERN Document Server

    Hessler, C; Goddard, B; Meddahi, M; Weterings, W

    2009-01-01

    The LHC phase II collimation project requires beam shock and impact tests of materials used for beam intercepting devices. Similar tests are also of great interest for other accelerator components such as beam entrance/exit windows and protection devices. For this purpose a dedicated High Radiation Material test facility (HiRadMat) is under study. This facility may be installed at CERN at the location of a former beam line. This paper describes the associated beam line which is foreseen to deliver a 450 GeV proton beam from the SPS with an intensity of up to 3×1013 protons per shot. Different beam line designs will be compared and the choice of the beam steering and diagnostic elements will be discussed, as well as operational issues.

  12. Beam Line Design for the CERN Hiradmat Test Facility

    CERN Document Server

    Hessler, C; Goddard, B; Meddahi, M; Weterings, W

    2010-01-01

    The LHC phase II collimation project requires beam shock and impact tests of materials used for beam intercepting devices. Similar tests are also of great interest for other accelerator components such as beam entrance/exit windows and protection devices. For this purpose a dedicated High Radiation Material test facility (HiRadMat) is under study. This facility may be installed at CERN at the location of a former beam line. This paper describes the associated beam line which is foreseen to deliver a 450 GeV proton beam from the SPS with an intensity of up to 3×10**13 protons per shot. Different beam line designs will be compared and the choice of the beam steering and diagnostic elements will be discussed, as well as operational issues.

  13. ISOL based radioactive nuclear beam facilities

    International Nuclear Information System (INIS)

    Nomura, T.

    1991-07-01

    High-intensity and high-quality unstable nuclear beams can be realized by coupling an isotope separator on-line and a proper post accelerator in various primary beams. Some technical features and problems in the production of such beams are discussed. A brief description is given on 'Exotic Nuclei Arena' in Japanese Hadron Project. (author)

  14. A new slow positron beam facility using a compact cyclotron

    International Nuclear Information System (INIS)

    Hirose, Masafumi

    1998-01-01

    In 1993, Sumitomo Heavy Industries became the first in the world to successfully produce a slow positron beam using a compact cyclotron. Slow positron beam production using an accelerator had mainly consisted of using an electron linear accelerator (LINAC). However, the newly developed system that uses a compact cyclotron enabled cost reduction, downsizing of equipment, production of a DC slow positron beam, a polarized slow positron beam, and other benefits. After that, a genuine slow positron beam facility was developed with the construction of compact cyclotron No.2, and beam production in the new facility has already been started. The features of this new slow positron beam facility are explained below. 1) It is the world's first compact slow positron beam facility using a compact cyclotron. 2) It is the only genuine slow positron beam facility in the world which incorporates the production and use of a slow positron beam in the design stage of the cyclotron. To use a slow positron beam for non-destructive detection of lattice defects in semiconductor material, it is necessary to convert the beam into ultra-short pulses of several hundreds of pico-seconds. Sumitomo Heavy Industries has devised a new short-pulsing method (i.e. an induction bunching method) that enables the conversion of a slow positron beam into short pulses with an optimum pulsing electric field change, and succeeded in converting a slow positron beam into short pulses using this method for the first time in the world. Non-destructive detection of lattice defects in semiconductor material using this equipment has already been started, and some information about the depth distribution, size, density, etc. of lattice defects has already been obtained. (J.P.N.)

  15. Principles and practice of proton beam therapy

    CERN Document Server

    Das, Indra J

    2015-01-01

    Commissioned by The American Association of Physicists in Medicine (AAPM) for their June 2015 Summer School, this is the first AAPM monograph printed in full color. Proton therapy has been used in radiation therapy for over 70 years, but within the last decade its use in clinics has grown exponentially. This book fills in the proton therapy gap by focusing on the physics of proton therapy, including beam production, proton interactions, biology, dosimetry, treatment planning, quality assurance, commissioning, motion management, and uncertainties. Chapters are written by the world's leading medical physicists who work at the pioneering proton treatment centers around the globe. They share their understandings after years of experience treating thousands of patients. Case studies involving specific cancer treatments show that there is some art to proton therapy as well as state-of-the-art science. Even though the focus lies on proton therapy, the content provided is also valuable to heavy charged particle th...

  16. Proton and heavy ion beam (charged particle therapy)

    International Nuclear Information System (INIS)

    Kanai, Tatsuaki

    2003-01-01

    There are distinguished therapeutic irradiation facilities of proton and heavy ion beam in Japan. The beam, due to its physical properties, is advantageous for focusing on the lesion in the body and for reducing the exposure dose to normal tissues, relative to X-ray. This makes it possible to irradiate the target lesion with the higher dose. The present review describes physical properties of the beam, equipments for the therapeutic irradiation, the respiratory-gated irradiation system, the layer-stacking irradiation system, therapy planning, and future prospect of the therapy. More than 1,400 patients have received the therapy in National Institute of Radiological Sciences (NIRS) and given a good clinical outcome. The targets are cancers of the head and neck, lung, liver, uterine and prostate, and osteosarcoma. The therapy of osteosarcoma is particularly important, which bringing about the high cure rate. Severe adverse effects are not seen with exception for the digestive tract ulcer. Many attempts like the respiratory-gated and layer-stacking systems and to shorten the therapy period to within 1 week are in progress. (N.I.)

  17. Holifield Radioactive Ion Beam Facility Development and Status

    CERN Document Server

    Tatum, Alan

    2005-01-01

    The Holifield Radioactive Ion Beam Facility (HRIBF) is a national user facility dedicated to nuclear structure, reactions, and nuclear astrophysics research with radioactive ion beams (RIBs) using the isotope separator on-line (ISOL) technique. An integrated strategic plan for physics, experimental systems, and RIB production facilities have been developed and implementation of the plan is under way. Specific research objectives are defined for studying the nature of nucleonic matter, the origin of elements, solar physics, and synthesis of heavy elements. Experimental systems upgrade plans include new detector arrays and beam lines, and expansion and upgrade of existing devices. A multifaceted facility expansion plan includes a $4.75M High Power Target Laboratory (HPTL), presently under construction, to provide a facility for testing new target materials, target geometries, ion sources, and beam preparation techniques. Additional planned upgrades include a second RIB production system (IRIS2), an external axi...

  18. Drive beam stabilisation in the CLIC Test Facility 3

    Science.gov (United States)

    Malina, L.; Corsini, R.; Persson, T.; Skowroński, P. K.; Adli, E.

    2018-06-01

    The proposed Compact Linear Collider (CLIC) uses a high intensity, low energy drive beam to produce the RF power needed to accelerate a lower intensity main beam with 100 MV/m gradient. This scheme puts stringent requirements on drive beam stability in terms of phase, energy and current. The consequent experimental work was carried out in CLIC Test Facility CTF3. In this paper, we present a novel analysis technique in accelerator physics to find beam drifts and their sources in the vast amount of the continuously gathered signals. The instability sources are identified and adequately mitigated either by hardware improvements or by implementation and commissioning of various feedbacks, mostly beam-based. The resulting drive beam stability is of 0.2°@ 3 GHz in phase, 0.08% in relative beam energy and about 0.2% beam current. Finally, we propose a stabilisation concept for CLIC to guarantee the main beam stability.

  19. Accelerator development for a radioactive beam facility based on ATLAS

    International Nuclear Information System (INIS)

    Shepard, K. W.

    1998-01-01

    The existing superconducting linac ATLAS is in many respects an ideal secondary beam accelerator for an ISOL (Isotope separator on-line) type radioactive beam facility. Such a facility would require the addition of two major accelerator elements: a low charge state injector for the existing heavy ion linac, and a primary beam accelerator providing 220 MV of acceleration for protons and light ions. Development work for both of these elements, including the option of superconducting cavities for the primary beam accelerator is discussed

  20. Accelerator development for a radioactive beam facility based on ATLAS.

    Energy Technology Data Exchange (ETDEWEB)

    Shepard, K. W.

    1998-01-08

    The existing superconducting linac ATLAS is in many respects an ideal secondary beam accelerator for an ISOL (Isotope separator on-line) type radioactive beam facility. Such a facility would require the addition of two major accelerator elements: a low charge state injector for the existing heavy ion linac, and a primary beam accelerator providing 220 MV of acceleration for protons and light ions. Development work for both of these elements, including the option of superconducting cavities for the primary beam accelerator is discussed.

  1. Ion beam therapy fundamentals, technology, clinical applications

    CERN Document Server

    2012-01-01

    The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public an...

  2. The Swedish facility for boron neutron capture therapy

    Energy Technology Data Exchange (ETDEWEB)

    Skoeld, K.; Capala, J. [Studsvik Medical AB (Sweden); Kierkegaard, J.; Haakansson, R. [Studsvik Nuclear AB (Sweden); Gudowska, I. [Karolinska Institute (Sweden)

    2000-10-01

    A BNCT (Boron Neutron Capture Therapy) facility has been constructed at the R2-0 reactor at Studsvik, Sweden. R2-0 is a 1 MW, open core, pool reactor. The reactor core is suspended on a movable tower and can be positioned anywhere in the pool. The BNCT facility includes two adjacent, parallel filter/moderator configurations and the reactor core is positioned in front of any of them as appropriate. One of the resulting neutron beams has been optimized for clinical irradiations with a filter/moderator system that allows easy variation of the neutron spectrum from the thermal to the epithermal energy range and with an extended collimator for convenient patient positioning. The other beam has been designed for radiobiological research and is equipped with a heavy water moderator and a large irradiation cavity with a uniform field of thermal neutrons. (author)

  3. The Swedish facility for boron neutron capture therapy

    International Nuclear Information System (INIS)

    Skoeld, K.; Capala, J.; Kierkegaard, J.; Haakansson, R.; Gudowska, I.

    2000-01-01

    A BNCT (Boron Neutron Capture Therapy) facility has been constructed at the R2-0 reactor at Studsvik, Sweden. R2-0 is a 1 MW, open core, pool reactor. The reactor core is suspended on a movable tower and can be positioned anywhere in the pool. The BNCT facility includes two adjacent, parallel filter/moderator configurations and the reactor core is positioned in front of any of them as appropriate. One of the resulting neutron beams has been optimized for clinical irradiations with a filter/moderator system that allows easy variation of the neutron spectrum from the thermal to the epithermal energy range and with an extended collimator for convenient patient positioning. The other beam has been designed for radiobiological research and is equipped with a heavy water moderator and a large irradiation cavity with a uniform field of thermal neutrons. (author)

  4. Microdosimetric investigations at the fast neutron therapy facility at Fermilab

    International Nuclear Information System (INIS)

    Langen, K.M.

    1997-01-01

    Microdosimetry was used to investigate three issues at the neutron therapy facility (NTF) at Fermilab. Firstly, the conversion factor from absorbed dose in A-150 tissue equivalent plastic to absorbed dose in ICRU tissue was determined. For this, the effective neutron kerma factor ratios, i.e., oxygen tissue equivalent plastic and carbon to A-150 tissue equivalent plastic, were measured in the neutron beam. An A-150 tissue equivalent plastic to ICRU tissue absorbed dose conversion factor of 0.92 ± 0.04 was determined. Secondly, variations in the radiobiological effectiveness (RBE) in the beam were mapped by determining variations in two related quantities, e * and R, with field size and depth in tissue. Maximal variation in e * and R of 9% and 15% respectively were determined. Lastly, the feasibility of utilizing the boron neutron capture reaction on boron-10 to selectively enhance the tumor dose in the NTF beam was investigated

  5. Extraction and beam transfer for the SHiP facility

    CERN Document Server

    Goddard, Brennan; Borburgh, Jan; Balhan, Bruno; Le Godec, Gilles; Zerlauth, Markus; Tommasini, Davide; Kain, Verena; Cornelis, Karel; Wenninger, Jorg; Jensen, Lars; Todd, Benjamin; Bauche, Jeremie; Puccio, Bruno

    2015-01-01

    This document summarises the key feasibility issues associated with the SPS extraction and beam transfer systems required for the SHiP facility. It describes the expected performance limits of the electrostatic septa, the expected beam losses during extraction and consequences, the design of the new beamline geometry and equipment systems and the expected extracted spill structure.

  6. ECR ion source based low energy ion beam facility

    Indian Academy of Sciences (India)

    Mass analyzed highly charged ion beams of energy ranging from a few keV to a few MeV plays an important role in various aspects of research in modern physics. In this paper a unique low energy ion beam facility (LEIBF) set up at Nuclear Science Centre (NSC) for providing low and medium energy multiply charged ion ...

  7. A standardized method for beam design in neutron capture therapy

    International Nuclear Information System (INIS)

    Storr, G.J.: Harrington, B.V.

    1993-01-01

    A desirable end point for a given beam design for Neutron Capture Therapy (NCT) should be quantitative description of tumour control probability and normal tissue damage. Achieving this goal will ultimately rely on data from NCT human clinical trials. Traditional descriptions of beam designs have used a variety of assessment methods to quantify proposed or installed beam designs. These methods include measurement and calculation of open-quotes free fieldclose quotes parameters, such as neutron and gamma flux intensities and energy spectra, and figures-of-merit in tissue equivalent phantoms. The authors propose here a standardized method for beam design in NCT. This method would allow all proposed and existing NCT beam facilities to be compared equally. The traditional approach to determining a quantitative description of tumour control probability and normal tissue damage in NCT research may be described by the following path: Beam design → dosimetry → macroscopic effects → microscopic effects. Methods exist that allow neutron and gamma fluxes and energy dependence to be calculated and measured to good accuracy. By using this information and intermediate dosimetric quantities such as kerma factors for neutrons and gammas, macroscopic effect (absorbed dose) in geometries of tissue or tissue-equivalent materials can be calculated. After this stage, for NCT the data begins to become more sparse and in some areas ambiguous. Uncertainties in the Relative Biological Effectiveness (RBE) of some NCT dose components means that beam designs based on assumptions considered valid a few years ago may have to be reassessed. A standard method is therefore useful for comparing different NCT facilities

  8. Radionuclide therapy practice and facilities in Europe

    International Nuclear Information System (INIS)

    Hoefnagel, C.A.; Clarke, S.E.M.; Fischer, M.; Chatal, J.F.; Lewington, V.J.; Nilsson, S.; Troncone, L.; Vieira, M.R.

    1999-01-01

    Using a questionnaire the EANM Task Group Radionuclide Therapy in 1993 collected data on the current practice of radionuclide therapy in European countries. Subsequently, at the request of the EANM Executive Committee, the EANM Radionuclide Therapy Committee has made an inventory of the distribution of facilities for radionuclide therapy and undertaken an assessment of the total number of patients treated throughout Europe and of the types of treatment provides, with the aim of supporting the development of policy to adjust the available capacity to the needs by the year 2000. For this purpose, a second, more detailed questionnaire was sent out the members and national advisors of the Committee (see below), who gathered the data for each country that was a member of the EANM at the time. It is concluded that a wide bariation in therapy practice exists across Europe, particularly in the utilisation of radionuclide therapy, the requirement and availability of proper isolation facilities and the background training of those undertaking therapy. More uniform guidelines and legislation are required, although changes in legislation may have a significant impact in some countries. Although there is wide variation in the therapies used in each country, one the whole it appears that there is an underutilisation of nuclear medicine as a therapeutic modality. A rapidly increasing role may be expected, in particular for oncological indications requiring high-dose radionuclide treatment. Therefore there is an urgent need for a greater number of isolation beds in dedicated centers throughout Europe

  9. ISOL science at the Holifield Radioactive Ion Beam Facility

    Energy Technology Data Exchange (ETDEWEB)

    Beene, James R [ORNL; Bardayan, Daniel W [ORNL; Galindo-Uribarri, Alfredo {nmn} [ORNL; Gross, Carl J [ORNL; Jones, K. L. [University of Tennessee, Knoxville (UTK); Liang, J Felix [ORNL; Nazarewicz, Witold [ORNL; Stracener, Daniel W [ORNL; Tatum, B Alan [ORNL; Varner Jr, Robert L [ORNL

    2011-01-01

    The Holi eld Radioactive Ion Beam Facility, located in Oak Ridge, Tennessee, is operated as a National User Facility for the U.S. Department of Energy, producing high quality ISOL beams of short-lived, radioactive nuclei for studies of exotic nuclei, astrophysics research, and various societal applications. The primary driver, the Oak Ridge Isochronous Cyclotron, produces rare isotopes by bombarding highly refractory targets with light ions. The radioactive isotopes are ionized, formed into a beam, mass selected, injected into the 25-MV Tandem, accelerated, and used in experiments. This article reviews HRIBF and its science.

  10. An irradiation facility with a horizontal beam for radiobiological studies

    International Nuclear Information System (INIS)

    Czub, J.; Banas, D.; Braziewicz, J.; Choinski, J.; Jaskola, M.; Korman, A.; Szeflinski, Z.; Wojcik, A.

    2006-01-01

    A facility with a horizontal beam for radiobiological experiments with heavy ions has been designed and constructed at the Heavy Ion Laboratory in Warsaw Univ.. The facility is optimal to investigate the radiobiological effects of charged heavy particles on a cellular or molecular level as in the region of the Bragg peak. (authors)

  11. Synthetic methods for beam to beam power balancing capability of large laser facilities

    International Nuclear Information System (INIS)

    Chen Guangyu; Zhang Xiaomin; Zhao Runchang; Zheng Wanguo; Yang Xiaoyu; You Yong; Wang Chengcheng; Shao Yunfei

    2011-01-01

    To account for output power balancing capability of large laser facilities, a synthetic method with beam to beam root-mean-square is presented. Firstly, a conversion process for the facilities from original data of beam powers to regular data is given. The regular data contribute to the normal distribution approximately, and then a corresponding simple method of root-mean-square for beam to beam power balancing capability is given.Secondly, based on theory of total control charts and cause-selecting control charts, control charts with root-mean-square are established which show short-term variety of power balancing capability of the facilities. Mean rate of failure occurrence is also defined and used to describe long-term trend of global balancing capabilities of the facilities. Finally, advantages of the intuitive and efficient diagnosis for synthetic methods are illustrated by analysis of experimental data. (authors)

  12. Repeated proton beam therapy for hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Hashimoto, Takayuki; Tokuuye, Koichi; Fukumitsu, Nobuyoshi; Igaki, Hiroshi; Hata, Masaharu; Kagei, Kenji; Sugahara, Shinji; Ohara, Kiyoshi; Matsuzaki, Yasushi; Akine, Yasuyuki

    2006-01-01

    Purpose: To retrospectively evaluate the safety and effectiveness of repeated proton beam therapy for newly developed or recurrent hepatocellular carcinoma (HCC). Methods and Materials: From June 1989 through July 2000, 225 patients with HCC underwent their first course of proton beam therapy at University of Tsukuba. Of them, 27 with 68 lesions who had undergone two or more courses were retrospectively reviewed in this study. Median interval between the first and second course was 24.5 months (range 3.3-79.8 months). Median total dose of 72 Gy in 16 fractions and 66 Gy in 16 fractions were given for the first course and the rest of the courses, respectively. Results: The 5-year survival rate and median survival period from the beginning of the first course for the 27 patients were 55.6% and 62.2 months, respectively. Five-year local control rate for the 68 lesions was 87.8%. Of the patients, 1 with Child-Pugh class B and another with class C before the last course suffered from acute hepatic failure. Conclusions: Repeated proton beam therapy for HCC is safe when the patient has a target in the peripheral region of the liver and liver function is Child-Pugh class A

  13. Beam Characterization at the Neutron Radiography Facility

    Energy Technology Data Exchange (ETDEWEB)

    Sarah Morgan; Jeffrey King

    2013-01-01

    The quality of a neutron imaging beam directly impacts the quality of radiographic images produced using that beam. Fully characterizing a neutron beam, including determination of the beam’s effective length-to-diameter ratio, neutron flux profile, energy spectrum, image quality, and beam divergence, is vital for producing quality radiographic images. This project characterized the east neutron imaging beamline at the Idaho National Laboratory Neutron Radiography Reactor (NRAD). The experiments which measured the beam’s effective length-to-diameter ratio and image quality are based on American Society for Testing and Materials (ASTM) standards. An analysis of the image produced by a calibrated phantom measured the beam divergence. The energy spectrum measurements consist of a series of foil irradiations using a selection of activation foils, compared to the results produced by a Monte Carlo n-Particle (MCNP) model of the beamline. Improvement of the existing NRAD MCNP beamline model includes validation of the model’s energy spectrum and the development of enhanced image simulation methods. The image simulation methods predict the radiographic image of an object based on the foil reaction rate data obtained by placing a model of the object in front of the image plane in an MCNP beamline model.

  14. Accelerator complex for a radioactive ion beam facility at ATLAS

    International Nuclear Information System (INIS)

    Nolen, J.A.

    1995-01-01

    Since the superconducting heavy ion linac ATLAS is an ideal post-accelerator for radioactive beams, plans are being developed for expansion of the facility with the addition of a driver accelerator, a production target/ion source combination, and a low q/m pre-accelerator for radioactive ions. A working group including staff from the ANL Physics Division and current ATLAS users are preparing a radioactive beam facility proposal. The present paper reviews the specifications of the accelerators required for the facility

  15. Overview of linac applications at future radioactive beam facilities

    International Nuclear Information System (INIS)

    Nolen, J.A.

    1996-01-01

    There is considerable interest worldwide in the research which could be done at a next generation, advanced radioactive beam facility. To generate high quality, intense beams of accelerated radionuclides via the open-quotes isotope separator on-lineclose quotes (ISOL) method requires two major accelerator components: a high power (100 kW) driver device to produce radionuclides in a production target/ion source complex, and a secondary beam accelerator to produce beams of radioactive ions up to energies on the order of 10 MeV per nucleon over a broad mass range. In reviewing the technological challenges of such a facility, several types of modem linear accelerators appear well suited. This paper reviews the properties of the linacs currently under construction and those proposed for future facilities for use either as the driver device or the radioactive beam post-accelerator. Other choices of accelerators, such as cyclotrons, for either the driver or secondary beam devices of a radioactive beam complex will also be compared. Issues to be addressed for the production accelerator include the choice of ion beam types to be used for cost-effective production of radionuclides. For the post-accelerator the choice of ion source technology is critical and dictates the charge-to-mass requirements at the injection stage

  16. Beam position and phase measurements of microampere beams at the Michigan State University REA3 facility

    CERN Document Server

    Crisp, J; Durickovic, B; Kiupel, G; Krause, S; Leitner, D; Nash, S; Rodriguez, J A; Russo, T; Webber, R; Wittmer, W; Eddy, N; Briegel, C; Fellenz, B; Slimmer, D; Wendt, M

    2013-01-01

    A high power CW, heavy ion linac will be the driver accelerator for the Facility for Rare Isotope Beams (FRIB) being designed at Michigan State University (MSU). The linac requires a Beam Position Monitoring (BPM) system with better than 100 micron resolution at 100 microamperes beam current. A low beam current test of the candidate technology, button pick-ups and direct digital down-conversion signal processing, was conducted in the ReA3 re-accelerated beam facility at Michigan State University. The test is described. Beam position and phase measurement results, demonstrating ~250 micron and ~1.5 degree resolution in a 45 kHz bandwidth for a 1.0 microampere beam current, are reported.

  17. Data acquisition system for medium power neutral beam test facility

    International Nuclear Information System (INIS)

    Stewart, C.R. Jr.; Francis, J.E. Jr.; Hammons, C.E.; Dagenhart, W.K.

    1978-06-01

    The Medium Power Neutral Beam Test Facility at Oak Ridge National Laboratory was constructed in order to develop, test, and condition powerful neutral beam lines for the Princeton Large Torus experiment at Princeton Plasma Physics Laboratory. The data acquisition system for the test stand monitors source performance, beam characteristics, and power deposition profiles to determine if the beam line is operating up to its design specifications. The speed of the computer system is utilized to provide near-real-time analysis of experimental data. Analysis of the data is presented as numerical tabulation and graphic display

  18. Proton therapy detector studies under the experience gained at the CATANA facility

    International Nuclear Information System (INIS)

    Cuttone, G.; Cirrone, G.A.P.; Di Rosa, F.; Lojacono, P.A.; Lo Nigro, S.; Marino, C.; Mongelli, V.; Patti, I.V.; Pittera, S.; Raffaele, L.; Russo, G.; Sabini, M.G.; Salamone, V.; Valastro, L.M.

    2007-01-01

    Proton therapy represents the most promising radiotherapy technique for external tumor treatments. At Laboratori Nazionali del Sud of the Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania (I), a proton therapy facility is active since March 2002 and 140 patients, mainly affected by choroidal and iris melanoma, have been successfully treated. Proton beams are characterized by higher dose gradients and linear energy transfer with respect to the conventional photon and electron beams, commonly used in medical centers for radiotherapy. In this paper, we report the experience gained in the characterization of different dosimetric systems, studied and/or developed during the last ten years in our proton therapy facility

  19. Proton therapy detector studies under the experience gained at the CATANA facility

    Energy Technology Data Exchange (ETDEWEB)

    Cuttone, G.; Cirrone, G.A.P.; Di Rosa, F. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Lojacono, P.A. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Lo Nigro, S.; Marino, C. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Centro Siciliano di Fisica Nucleare e Struttura della Materia, Catania (Italy); Mongelli, V. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Patti, I.V. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Pittera, S. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Centro Siciliano di Fisica Nucleare e Struttura della Materia, Catania (Italy); Raffaele, L. [A.O.U. Policlinico, Universita degli Studi di Catania (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Russo, G. [Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Dipartimento di Fisica ed Astronomia, Universita degli Studi di Catania (Italy); Sabini, M.G. [A.O. Cannizzaro, Catania (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy); Salamone, V.; Valastro, L.M. [A.O.U. Policlinico, Universita degli Studi di Catania (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali dei Sud, Catania (Italy)

    2007-10-15

    Proton therapy represents the most promising radiotherapy technique for external tumor treatments. At Laboratori Nazionali del Sud of the Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania (I), a proton therapy facility is active since March 2002 and 140 patients, mainly affected by choroidal and iris melanoma, have been successfully treated. Proton beams are characterized by higher dose gradients and linear energy transfer with respect to the conventional photon and electron beams, commonly used in medical centers for radiotherapy. In this paper, we report the experience gained in the characterization of different dosimetric systems, studied and/or developed during the last ten years in our proton therapy facility.

  20. Proton therapy detector studies under the experience gained at the CATANA facility

    Science.gov (United States)

    Cuttone, G.; Cirrone, G. A. P.; Di Rosa, F.; Lojacono, P. A.; Lo Nigro, S.; Marino, C.; Mongelli, V.; Patti, I. V.; Pittera, S.; Raffaele, L.; Russo, G.; Sabini, M. G.; Salamone, V.; Valastro, L. M.

    2007-10-01

    Proton therapy represents the most promising radiotherapy technique for external tumor treatments. At Laboratori Nazionali del Sud of the Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania (I), a proton therapy facility is active since March 2002 and 140 patients, mainly affected by choroidal and iris melanoma, have been successfully treated. Proton beams are characterized by higher dose gradients and linear energy transfer with respect to the conventional photon and electron beams, commonly used in medical centers for radiotherapy.In this paper, we report the experience gained in the characterization of different dosimetric systems, studied and/or developed during the last ten years in our proton therapy facility.

  1. CERN AWAKE Facility Readiness for First Beam

    CERN Document Server

    Bracco, Chiara; Butterworth, Andrew; Damerau, Heiko; Döbert, Steffen; Fedosseev, Valentin; Feldbaumer, Eduard; Gschwendtner, Edda; Höfle, Wolfgang; Pardons, Ans; Shaposhnikova, Elena; Vincke, Helmut

    2016-01-01

    The AWAKE project at CERN was approved in August 2013 and since then a big effort was made to be able to probe the acceleration of electrons before the "2019-2020 Long Shutdown". The next steps in this challenging schedule will be a dry run of all the beam line systems, at the end of the HW commissioning in June 2016, and the first proton beam sent to the plasma cell one month later. The current status of the project is presented together with an outlook over the foreseen works for operation with electrons in 2018.

  2. National facility for neutron beam research

    Indian Academy of Sciences (India)

    In this talk, the growth of neutron beam research (NBR) in India over the past five decades is traced beginning with research at Apsara. A range of problems in condensed matter physics could be studied at CIRUS, followed by sophisticated indegenous instrumentation and research at Dhruva. The talk ends with an overview ...

  3. The ISOLDE Facility: Radioactive beams at CERN

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    Some of the experimental techniques used will be introduced; more focus will be put on what physics questions can be answered by using radioactive beams. A brief overview is given of the present and future European developments in this rapidly evolving field. Prerequisite knowledge: none

  4. Neutron field characterization and dosimetry at the TRIUMF proton therapy facility

    International Nuclear Information System (INIS)

    Mukherjee, B.

    2002-01-01

    Full text: In 1972 the 500 MeV H' Cyclotron of the TRIUMF (Tri University Meson Factory) located in Vancouver, Canada became operational. Beside Meson Physics, high-energy protons of various energy and beam current levels from the TRIUMF Cyclotron are used for scientific research and biomedical applications. Recently, a 500 MeV proton beam from the cyclotron was used as the booster beam for the radioactive ion beam facility, ISAC (Isotope Separator Accelerator) and a second beam as primary irradiation source for the Proton Irradiation Facility (PIF). The major commercial applications of the PIF are the provision of high-energy proton beams for radiation hardness testing of electronic components used in space applications (NASA) and proton therapy of ocular tumors (British Columbia Proton Therapy Facility). The PIF vault was constructed within the main accelerator hall of the TRIUMF using stacks of large concrete blocks. An intense field of fast neutrons is produced during the interaction of high-energy proton beam with target materials, such as, beam stops, collimators and beam energy degraders. The leakage of such neutrons due to insufficient radiological shielding or through the shielding discontinuities may constitute a major share of the personnel radiation exposure of the radiation workers. The neutron energy distribution and dose equivalent near a lead beam stopper bombarded with 116 MeV and 65 MeV collimated proton beams at the Ocular Tumor irradiation facility were evaluated using a Bonner-Sphere Spectrometer and a REM counter respectively. The results were utilized to investigate efficacy of the existing radiological shielding of the PIF. This paper highlights experimental methods to analyze the high-energy accelerator produced neutron beam and basic guideline for the radiological shielding designs of irradiation vault of Proton Therapy facilities

  5. Proton-Beam Therapy for Olfactory Neuroblastoma

    International Nuclear Information System (INIS)

    Nishimura, Hideki; Ogino, Takashi; Kawashima, Mitsuhiko; Nihei, Keiji; Arahira, Satoko; Onozawa, Masakatsu; Katsuta, Shoichi; Nishio, Teiji

    2007-01-01

    Purpose: To analyze the feasibility and efficacy of proton-beam therapy (PBT) for olfactory neuroblastoma (ONB) as a definitive treatment, by reviewing our preliminary experience. Olfactory neuroblastoma is a rare disease, and a standard treatment strategy has not been established. Radiation therapy for ONB is challenging because of the proximity of ONBs to critical organs. Proton-beam therapy can provide better dose distribution compared with X-ray irradiation because of its physical characteristics, and is deemed to be a feasible treatment modality. Methods and Materials: A retrospective review was performed on 14 patients who underwent PBT for ONB as definitive treatment at the National Cancer Center Hospital East (Kashiwa, Chiba, Japan) from November 1999 to February 2005. A total dose of PBT was 65 cobalt Gray equivalents (Gy E ), with 2.5-Gy E once-daily fractionations. Results: The median follow-up period for surviving patients was 40 months. One patient died from disseminated disease. There were two persistent diseases, one of which was successfully salvaged with surgery. The 5-year overall survival rate was 93%, the 5-year local progression-free survival rate was 84%, and the 5-year relapse-free survival rate was 71%. Liquorrhea was observed in one patient with Kadish's stage C disease (widely destroying the skull base). Most patients experienced Grade 1 to 2 dermatitis in the acute phase. No other adverse events of Grade 3 or greater were observed according to the RTOG/EORTC acute and late morbidity scoring system. Conclusions: Our preliminary results of PBT for ONB achieved excellent local control and survival outcomes without serious adverse effects. Proton-beam therapy is considered a safe and effective modality that warrants further study

  6. Defocusing beam line design for an irradiation facility at the TAEA SANAEM Proton Accelerator Facility

    Science.gov (United States)

    Gencer, A.; Demirköz, B.; Efthymiopoulos, I.; Yiğitoğlu, M.

    2016-07-01

    Electronic components must be tested to ensure reliable performance in high radiation environments such as Hi-Limu LHC and space. We propose a defocusing beam line to perform proton irradiation tests in Turkey. The Turkish Atomic Energy Authority SANAEM Proton Accelerator Facility was inaugurated in May 2012 for radioisotope production. The facility has also an R&D room for research purposes. The accelerator produces protons with 30 MeV kinetic energy and the beam current is variable between 10 μA and 1.2 mA. The beam kinetic energy is suitable for irradiation tests, however the beam current is high and therefore the flux must be lowered. We plan to build a defocusing beam line (DBL) in order to enlarge the beam size, reduce the flux to match the required specifications for the irradiation tests. Current design includes the beam transport and the final focusing magnets to blow up the beam. Scattering foils and a collimator is placed for the reduction of the beam flux. The DBL is designed to provide fluxes between 107 p /cm2 / s and 109 p /cm2 / s for performing irradiation tests in an area of 15.4 cm × 21.5 cm. The facility will be the first irradiation facility of its kind in Turkey.

  7. The beam diagnostic instruments in Beijing radioactive ion-beam facilities isotope separator on-line

    International Nuclear Information System (INIS)

    Ma, Y.; Cui, B.; Ma, R.; Tang, B.; Chen, L.; Huang, Q.; Jiang, W.

    2014-01-01

    The beam diagnostic instruments for Beijing Radioactive Ion-beam Facilities Isotope Separator On-Line are introduced [B. Q. Cui, Z. H. Peng, Y. J. Ma, R. G. Ma, B. Tang, T. Zhang, and W. S. Jiang, Nucl. Instrum. Methods 266, 4113 (2008); T. J. Zhang, X. L. Guan, and B. Q. Cui, in Proceedings of APAC 2004, Gyeongju, Korea, 2004, http://www.jacow.org , p. 267]. For low intensity ion beam [30–300 keV/1 pA–10 μA], the beam profile monitor, the emittance measurement unit, and the analyzing slit will be installed. For the primary proton beam [100 MeV/200 μA], the beam profile scanner will be installed. For identification of the nuclide, a beam identification unit will be installed. The details of prototype of the beam diagnostic units and some experiment results will be described in this article

  8. Muon Beam Studies in the H4 beam line and the Gamma Irradiation Facility (GIF++)

    CERN Document Server

    Margraf, Rachel; CERN. Geneva. ATS Department

    2018-01-01

    In this note, we present detailed simulation results for the trajectory of a muon beam, traversing beam zones PPE-134 and PPE-154, produced by a 150 GeV positive hadron beam incident on collimators 9 & 10 in the H4 beam line when these collimators are placed off-beam axis to stop all hadrons and electrons. Using G4Beamline, a GEANT-4 based Monte-Carlo program, the trajectory of the muon beam has been studied for several field strengths of the GOLIATH magnet, as well as for different polarities. The position of the beam at the Gamma Irradiation Facility (GIF++), located downstream the PPE-144 area, is also presented. In addition, two configurations of the two XTDV’s present in the line (XTDV.022.520 and XTDV.022.610) have been studied, with the purpose to simulate the pion contamination of the beam both in PPE134 and GIF++.

  9. Muon Beam Studies in the H4 beam line and the Gamma Irradiation Facility (GIF++)

    CERN Document Server

    Margraf, Rachel; CERN. Geneva. EN Department

    2017-01-01

    In this report, I summarize my work of detailed study and optimization of the muon beam configuration of H4 beam line in SPS North Area. Using Monte-Carlo simulations, I studied the properties and behavior of the muon beam in combination with the field of the large, spectrometer “ GOLIATH” magnet at -1.5, -1.0, 0, 1.0 and 1.5 Tesla, which is shown to affect the central x position of the muon beam that is delivered to the Gamma Irradiation Facility (GIF++). I also studied the muon beam for different configurations of the two XTDV beam dumps upstream of GIF++ in the H4 beam line. I will also discuss my role in mapping the magnetic field of the GOLIATH magnet in the H4 beam line.

  10. Dual-beam operation of the Astra Gemini laser facility

    International Nuclear Information System (INIS)

    Bryan Parry; Nicola Booth; Oleg Chekhlov; John Collier; Edwin Divall; Klaus Ertel; Peta Foster; Steve Hawkes; Chris Hooker; Victoria Marshall

    2010-01-01

    Complete text of publication follows. Gemini is a Petawatt class Ti:Sapphire laser system at the Rutherford Appleton Laboratory, UK. It was designed as a dual beam laser, with two independently configurable 800 nm beams delivering 15 J to target in 30 fs pulse duration, giving 0.5 PW peak power per beam. It is capable of reaching intensities over 10 22 W/cm 2 . Gemini can achieve a maximum repetition rate of one shot every 20 seconds, allowing it to deliver hundreds of shots per day; a feature which makes it unique among PW lasers. Already this has proved valuable in experiments involving electron acceleration in gas jets. The first Gemini beamline became operational in 2008. Commissioning of the second beam was deferred to allow earlier access to the facility by experimental scientists, and to develop operational experience. In this mode, Gemini has already produced significant results from a number of advanced plasma physics experiments. The second beam of Gemini is now coming online, with the first dual beam experiment starting in June 2010. The flexibility offered by two short pulse, ultra high intensity beams is another aspect that makes this laser system unique. The dual beams enable versatile configurations and illumination geometries, facilitating a wider range of experiments than is possible with only a single beam. Operationally however, it introduces additional factors which must be monitored and controlled in order to achieve experimental success. The beams must be timed with respect to each other with accuracy less than the pulse duration. The beam foci must also be overlapped spatially, and the stability of both these factors maintained over extended periods. We report on the second beam commissioning process, including the latest results on the characteristics, stability and spatio-temporal overlap of the two beams. We present details of amplifier performance, along with measurements of beam quality, focal spot, pulse duration and contrast, to give a

  11. Spallation RI beam facility and heavy element nuclear chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Nagame, Yuichiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-11-01

    An outline of the spallation RI (Radioactive Ion) beam facility is presented. Neutron-rich nuclides are produced in the reaction of high intensity (10-1000 {mu}A) protons with energy of 1.5 GeV and an uranium carbide target. Produced nuclides are ionized in an isotope separator on-line (ISOL) and accelerated by the JAERI tandem and the booster linac. Current progress and a future project on the development of the RI beam facility are given. Studies of transactinide elements, including the synthesis of superheavy elements, nuclear structure far from stability, and RI-probed material science are planned with RI beams. An outlook of the transactinide nuclear chemistry studies using neutron-rich RI beams is described. (author)

  12. The high-energy dual-beam facility

    International Nuclear Information System (INIS)

    Kaletta, D.

    1984-07-01

    This proposal presents a new experimental facility at the Kernforschungszentrum Karlsruhe (KfK) to study the effects of irradiation on the first wall and blanket materials of a fusion reactor. A special effort is made to demonstrate the advantages of the Dual Beam Technique (DBT) as a future research tool for materials development within the European Fusion Technology Programme. The Dual-Beam-Technique allows the production both of helium and of damage in thick metal and ceramic specimens by simultaneous irradiation with high energy alpha particles and protons produced by the two KfK cyclotrons. The proposal describes the Dual Beam Technique the planned experimental activities and the design features of the Dual Beam Facility presently under construction. (orig.) [de

  13. Microdosimetric investigation at the therapeutic proton beam facility of CATANA.

    Science.gov (United States)

    De Nardo, L; Moro, D; Colautti, P; Conte, V; Tornielli, G; Cuttone, G

    2004-01-01

    Proton beams (62 Mev) are used by the Laboratori Nazionali del Sud of the Italian Institute of Nuclear Physics to treat eye melanoma tumours at the therapeutic facility called CATANA. A cylindrical slim tissue-equivalent proportional counter (TEPC) of 2.7 mm external diameter has been used to compare the radiation quality of two spread-out Bragg peaks (SOBP) at the CATANA proton beam.

  14. Microdosimetric investigation at the therapeutic proton beam facility of Catana

    International Nuclear Information System (INIS)

    De Nardo, L.; Moro, D.; Colautti, P.; Conte, V.; Tornielli, G.; Cuttone, G.

    2004-01-01

    Proton beams (62 Mev) are used by the Laboratori Nazionali del Sud of the Italian Inst. of Nuclear Physics to treat eye melanoma tumours at the therapeutic facility called CATANA. A cylindrical slim tissue-equivalent proportional counter (TEPC) of 2.7 mm external diameter has been used to compare the radiation quality of two spread-out Bragg peaks (SOBP) at the CATANA proton beam. (authors)

  15. Ion beams from high-current PF facilities

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, M [Soltan Inst. for Nuclear Studies, Otwock-Swierk (Poland)

    1997-12-31

    Pulsed beams of fast deuterons and impurity or admixture ions emitted from high-current PF-type facilities operated in different laboratories are dealt with. A short comparative analysis of time-integrated and time-resolved studies is presented. Particular attention is paid to the microstructure of such ion beams, and to the verification of some theoretical models. (author). 5 figs., 19 refs.

  16. Quantitative analysis of beam delivery parameters and treatment process time for proton beam therapy

    International Nuclear Information System (INIS)

    Suzuki, Kazumichi; Gillin, Michael T.; Sahoo, Narayan; Zhu, X. Ronald; Lee, Andrew K.; Lippy, Denise

    2011-01-01

    Purpose: To evaluate patient census, equipment clinical availability, maximum daily treatment capacity, use factor for major beam delivery parameters, and treatment process time for actual treatments delivered by proton therapy systems. Methods: The authors have been recording all beam delivery parameters, including delivered dose, energy, range, spread-out Bragg peak widths, gantry angles, and couch angles for every treatment field in an electronic medical record system. We analyzed delivery system downtimes that had been recorded for every equipment failure and associated incidents. These data were used to evaluate the use factor of beam delivery parameters, the size of the patient census, and the equipment clinical availability of the facility. The duration of each treatment session from patient walk-in and to patient walk-out of the treatment room was measured for 82 patients with cancers at various sites. Results: The yearly average equipment clinical availability in the last 3 yrs (June 2007-August 2010) was 97%, which exceeded the target of 95%. Approximately 2200 patients had been treated as of August 2010. The major disease sites were genitourinary (49%), thoracic (25%), central nervous system (22%), and gastrointestinal (2%). Beams have been delivered in approximately 8300 treatment fields. The use factor for six beam delivery parameters was also evaluated. Analysis of the treatment process times indicated that approximately 80% of this time was spent for patient and equipment setup. The other 20% was spent waiting for beam delivery and beam on. The total treatment process time can be expressed by a quadratic polynomial of the number of fields per session. The maximum daily treatment capacity of our facility using the current treatment processes was estimated to be 133 ± 35 patients. Conclusions: This analysis shows that the facility has operated at a high performance level and has treated a large number of patients with a variety of diseases. The use

  17. The ISOL exotic beam facility at LNS: the EXCYT project

    International Nuclear Information System (INIS)

    Ciavola, G.; Calabretta, L.; Cuttone, G.; Di Bartolo, G.; Finocchiaro, P.; Gammino, S.; Gu, M.; Migneco, E.; Raia, G.; Rifuggiato, D.; Rovelli, A.; Vinciguerra, D.; Qin, J.; Wollnik, H.

    1997-01-01

    The aim of the EXCYT project (exotics with cyclotron and tandem) is the development of a facility for producing and accelerating exotic beams from 0.2 up to 8 MeV/amu. EXCYT is based on the ''two accelerators'' method. A K=800 superconducting cyclotron, axially injected by the ECR ion source SERSE, will deliver the primary beam. Such a beam will produce the required nuclear species in a modified ISOLDE type target-source complex. When required, a 15 MV tandem Van der Graaff will accelerate the secondary beams. Both accelerators are existing and operational at Laboratorio Nazionale del Sud. Concerning the status of the project, progress has been made in most of the key issues of the project, like the construction of SERSE, cyclotron upgrading, modification of the existing building, high resolution mass separator, and diagnostic equipment for low energy, low intensity beams. (orig.)

  18. The ISOL exotic beam facility at LNS: the EXCYT project

    Energy Technology Data Exchange (ETDEWEB)

    Ciavola, G.; Calabretta, L.; Cuttone, G.; Di Bartolo, G.; Finocchiaro, P.; Gammino, S.; Gu, M.; Migneco, E.; Raia, G.; Rifuggiato, D.; Rovelli, A.; Vinciguerra, D. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Qin, J. [Institute of Atomic Energy, Beijing (China); Wollnik, H. [Giessen Univ. (Germany)

    1997-04-01

    The aim of the EXCYT project (exotics with cyclotron and tandem) is the development of a facility for producing and accelerating exotic beams from 0.2 up to 8 MeV/amu. EXCYT is based on the ``two accelerators`` method. A K=800 superconducting cyclotron, axially injected by the ECR ion source SERSE, will deliver the primary beam. Such a beam will produce the required nuclear species in a modified ISOLDE type target-source complex. When required, a 15 MV tandem Van der Graaff will accelerate the secondary beams. Both accelerators are existing and operational at Laboratorio Nazionale del Sud. Concerning the status of the project, progress has been made in most of the key issues of the project, like the construction of SERSE, cyclotron upgrading, modification of the existing building, high resolution mass separator, and diagnostic equipment for low energy, low intensity beams. (orig.). 8 refs.

  19. CERN accelerator school: Antiprotons for colliding beam facilities

    International Nuclear Information System (INIS)

    Bryant, P.; Newman, S.

    1984-01-01

    This is a specialized course which addresses a wide spectrum of theoretical and technological problems confronting the designer of an antiproton facility for high-energy-physics research. A broad and profound basis is provided by the lecturers' substantial experience gained over many years with CERN's unique equipment. Topics include beam optics, special lattices for antiproton accumulation and storage rings, antiproton production, stochastic cooling, acceleration and storage, r.f. noise, r.f. beam manipulations, beam-beam interaction, beam stability due to ion accumulation, and diagnostics. The SPS (Super Proton Synchrotron) panti p collider, LEAR (the Low Energy Antiproton Ring at CERN), antiprotons in the ISR (Intersecting Storage Rings), the new antiproton collector (ACOL) and gas jet targets are also discussed. A table is included listing the parameters of all CERN's accelerators and storage rings. See hints under the relevant topics. (orig./HSI)

  20. Prospects for high-power radioactive beam facilities worldwide

    CERN Document Server

    Nolen, Jerry A

    2003-01-01

    Advances in accelerators, targets, ion sources, and experimental instrumentation are making possible ever more powerful facilities for basic and applied research with short-lived radioactive isotopes. There are several current generation facilities, based on a variety of technologies, operating worldwide. These include, for example, those based on the in-flight method such as the recently upgraded National Superconducting Cyclotron Laboratory at Michigan State University, the facility at RIKEN in Japan, GANIL in Caen, France, and GSI in Darmstadt, Germany. Present facilities based on the Isotope-Separator On-Line method include, for example, the ISOLDE laboratory at CERN, HRIBF at Oak Ridge, and the new high-power facility ISAC at TRIUMF in Vancouver. Next-generation facilities include the Radioactive-Ion Factory upgrade of RIKEN to higher energy and intensity and the upgrade of ISAC to a higher energy secondary beam; both of these projects are in progress. A new project, LINAG, to upgrade the capabilities at...

  1. TU-G-BRCD-01: Will the High Cost of Proton Therapy Facilities Limit the Availability of Proton Therapy Treatment?

    Science.gov (United States)

    Maughan, R

    2012-06-01

    The potential dose distribution advantages associated with proton therapy, and particularly with pencil beam scanning (PBS) techniques, have lead to considerable interest in this modality in recent years. However, the large capital expenditure necessary for such a project requires careful financial consideration and business planning. The complexity of the beam delivery systems impacts the capital expenditure and the PBS only systems presently being advocated can reduce these costs. Also several manufacturers are considering "one-room" facilities as less expensive alternatives to multi-room facilities. This presentation includes a brief introduction to beam delivery options (passive scattering, uniform and modulated scanning) and some of the new technologies proposed for providing less expensive proton therapy systems. Based on current experience, data on proton therapy center start-up costs, running costs and the financial challenges associated with making this highly conformal therapy more widely available will be discussed. Issues associated with proton therapy implementation that are key to project success include strong project management, vendor cooperation and collaboration, staff recruitment and training. Time management during facility start up is a major concern, particularly in multi-room systems, where time must be shared between continuing vendor system validation, verification and acceptance testing, and user commissioning and patient treatments. The challenges associated with facility operation during this period and beyond are discussed, focusing on how standardization of process, downtime and smart scheduling can influence operational efficiency. 1. To understand the available choices for proton therapy facilities, the different beam delivery systems and the financial implications associated with these choices. 2. To understand the key elements necessary for successfully implementing a proton therapy program. 3. To understand the challenges

  2. Upgrading the AGS polarized beam facility

    International Nuclear Information System (INIS)

    Ratner, L.G.

    1991-01-01

    Although present techniques for crossing depolarizing resonances in circular accelerators work, they are very time-consuming to implement and were only able to provide about a 40% polarized beam at 22 GeV in the Alternating Gradient Synchrotron (AGS). We propose to install a partial ''Siberian Snake'' solenoid in the AGS to eliminate the need to correct imperfection resonances and to make other modifications in our intrinsic resonance correctors. This will allow us to reach an energy of 25 GeV with 70% polarization and will enable the AGS to be an efficient injector of polarized protons into the Relativistic Heavy Ion Collider (RHIC), as well as being able to carry on a fixed-target program with minimum set-up time. 3 refs., 5 figs., 1 tab

  3. Neutron beam facilities at the Replacement Research Reactor, ANSTO

    International Nuclear Information System (INIS)

    Kim, S.

    2003-01-01

    The exciting development for Australia is the construction of a modern state-of-the-art 20-MW Replacement Research Reactor which is currently under construction to replace the aging reactor (HIFAR) at ANSTO in 2006. To cater for advanced scientific applications, the replacement reactor will provide not only thermal neutron beams but also a modern cold-neutron source moderated by liquid deuterium at approximately -250 deg C, complete with provision for installation of a hot-neutron source at a later stage. The latest 'supermirror' guides will be used to transport the neutrons to the Reactor Hall and its adjoining Neutron Guide Hall where a suite of neutron beam instruments will be installed. These new facilities will expand and enhance ANSTO's capabilities and performance in neutron beam science compared with what is possible with the existing HIFAR facilities, and will make ANSTO/Australia competitive with the best neutron facilities in the world. Eight 'leading-edge' neutron beam instruments are planned for the Replacement Research Reactor when it goes critical in 2006, followed by more instruments by 2010 and beyond. Up to 18 neutron beam instruments can be accommodated at the Replacement Research Reactor, however, it has the capacity for further expansion, including potential for a second Neutron Guide Hall. The first batch of eight instruments has been carefully selected in conjunction with a user group representing various scientific interests in Australia. A team of scientists, engineers, drafting officers and technicians has been assembled to carry out the Neutron Beam Instrument Project to successful completion. Today, most of the planned instruments have conceptual designs and are now being engineered in detail prior to construction and procurement. A suite of ancillary equipment will also be provided to enable scientific experiments at different temperatures, pressures and magnetic fields. This paper describes the Neutron Beam Instrument Project and gives

  4. A Monte Carlo-based treatment-planning tool for ion beam therapy

    CERN Document Server

    Böhlen, T T; Dosanjh, M; Ferrari, A; Haberer, T; Parodi, K; Patera, V; Mairan, A

    2013-01-01

    Ion beam therapy, as an emerging radiation therapy modality, requires continuous efforts to develop and improve tools for patient treatment planning (TP) and research applications. Dose and fluence computation algorithms using the Monte Carlo (MC) technique have served for decades as reference tools for accurate dose computations for radiotherapy. In this work, a novel MC-based treatment-planning (MCTP) tool for ion beam therapy using the pencil beam scanning technique is presented. It allows single-field and simultaneous multiple-fields optimization for realistic patient treatment conditions and for dosimetric quality assurance for irradiation conditions at state-of-the-art ion beam therapy facilities. It employs iterative procedures that allow for the optimization of absorbed dose and relative biological effectiveness (RBE)-weighted dose using radiobiological input tables generated by external RBE models. Using a re-implementation of the local effect model (LEM), theMCTP tool is able to perform TP studies u...

  5. Overview of Light-Ion Beam Therapy

    International Nuclear Information System (INIS)

    Chu, William T.

    2006-01-01

    compared to those in conventional (photon) treatments. Wilson wrote his personal account of this pioneering work in 1997. In 1954 Cornelius Tobias and John Lawrence at the Radiation Laboratory (former E.O. Lawrence Berkeley National Laboratory) of the University of California, Berkeley performed the first therapeutic exposure of human patients to hadron (deuteron and helium ion) beams at the 184-Inch Synchrocyclotron. By 1984, or 30 years after the first proton treatment at Berkeley, programs of proton radiation treatments had opened at: University of Uppsala, Sweden, 1957; the Massachusetts General Hospital-Harvard Cyclotron Laboratory (MGH/HCL), USA, 1961; Dubna (1967), Moscow (1969) and St Petersburg (1975) in Russia; Chiba (1979) and Tsukuba (1983) in Japan; and Villigen, Switzerland, 1984. These centers used the accelerators originally constructed for nuclear physics research. The experience at these centers has confirmed the efficacy of protons and light ions in increasing the tumor dose relative to normal tissue dose, with significant improvements in local control and patient survival for several tumor sites. M.R. Raju reviewed the early clinical studies. In 1990, the Loma Linda University Medical Center in California heralded in the age of dedicated medical accelerators when it commissioned its proton therapy facility with a 250-MeV synchrotron. Since then there has been a relatively rapid increase in the number of hospital-based proton treatment centers around the world, and by 2006 there are more than a dozen commercially-built facilities in use, five new facilities under construction, and more in planning stages. In the 1950s larger synchrotrons were built in the GeV region at Brookhaven (3-GeV Cosmotron) and at Berkeley (6-GeV Bevatron), and today most of the world's largest accelerators are synchrotrons. With advances in accelerator design in the early 1970s, synchrotrons at Berkeley and Princeton accelerated ions with atomic numbers between 6 and 18, at

  6. Overview of Light-Ion Beam Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Chu, William T.

    2006-03-16

    treatment volume compared to those in conventional (photon) treatments. Wilson wrote his personal account of this pioneering work in 1997. In 1954 Cornelius Tobias and John Lawrence at the Radiation Laboratory (former E.O. Lawrence Berkeley National Laboratory) of the University of California, Berkeley performed the first therapeutic exposure of human patients to hadron (deuteron and helium ion) beams at the 184-Inch Synchrocyclotron. By 1984, or 30 years after the first proton treatment at Berkeley, programs of proton radiation treatments had opened at: University of Uppsala, Sweden, 1957; the Massachusetts General Hospital-Harvard Cyclotron Laboratory (MGH/HCL), USA, 1961; Dubna (1967), Moscow (1969) and St Petersburg (1975) in Russia; Chiba (1979) and Tsukuba (1983) in Japan; and Villigen, Switzerland, 1984. These centers used the accelerators originally constructed for nuclear physics research. The experience at these centers has confirmed the efficacy of protons and light ions in increasing the tumor dose relative to normal tissue dose, with significant improvements in local control and patient survival for several tumor sites. M.R. Raju reviewed the early clinical studies. In 1990, the Loma Linda University Medical Center in California heralded in the age of dedicated medical accelerators when it commissioned its proton therapy facility with a 250-MeV synchrotron. Since then there has been a relatively rapid increase in the number of hospital-based proton treatment centers around the world, and by 2006 there are more than a dozen commercially-built facilities in use, five new facilities under construction, and more in planning stages. In the 1950s larger synchrotrons were built in the GeV region at Brookhaven (3-GeV Cosmotron) and at Berkeley (6-GeV Bevatron), and today most of the world's largest accelerators are synchrotrons. With advances in accelerator design in the early 1970s, synchrotrons at Berkeley and Princeton accelerated ions with atomic numbers

  7. Fermilab Test Beam Facility Annual Report. FY 2014

    Energy Technology Data Exchange (ETDEWEB)

    Brandt, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States). et al.

    2015-01-01

    Fermilab Test Beam Facility (FTBF) operations are summarized for FY 2014. It is one of a series of publications intended to gather information in one place. In this case, the information concerns the individual experiments that ran at FTBF. Each experiment section was prepared by the relevant authors, and was edited for inclusion in this summary.

  8. The neutron beam facility at the Australian replacement research reactor

    International Nuclear Information System (INIS)

    Hunter, B.; Kennedy, S.

    1999-01-01

    Full text: The Australian federal government gave ANSTO final approval to build a research reactor to replace HIFAR on August 25th 1999. The replacement reactor is to be a multipurpose reactor with a thermal neutron flux of 3 x 10 14 n.cm -2 .s -1 and having improved capabilities for neutron beam research and for the production of radioisotopes for pharmaceutical, scientific and industrial use. The replacement reactor will commence operation in 2005 and will cater for Australian scientific, industrial and medical needs well into the 21st century. The scientific capabilities of the neutron beams at the replacement reactor are being developed in consultation with representatives from academia, industry and government research laboratories to provide a facility for condensed matter research in physics, chemistry, materials science, life sciences, engineering and earth sciences. Cold, thermal and hot neutron sources are to be installed, and neutron guides will be used to position most of the neutron beam instruments in a neutron guide hall outside the reactor confinement building. Eight instruments are planned for 2005, with a further three to be developed by 2010. A conceptual layout for the neutron beam facility is presented including the location of the planned suite of neutron beam instruments. The reactor and all the associated infrastructure, with the exception of the neutron beam instruments, is to be built by an accredited reactor builder in a turnkey contract. Tenders have been called for December 1999, with selection of contractor planned by June 2000. The neutron beam instruments will be developed by ANSTO and other contracted organisations in consultation with the user community and interested overseas scientists. The facility will be based, as far as possible, around a neutron guide hall that is be served by three thermal and three cold neutron guides. Efficient transportation of thermal and cold neutrons to the guide hall requires the use of modern super

  9. Developing of the protocol for electron beam food irradiation facility

    International Nuclear Information System (INIS)

    Petreska, Svetlana

    2012-01-01

    By establishing the needs for institution of new technologies in the process of food processing, in this case a randomized choice of electron beam accelerator facility, arises the need for designing a protocol for safe and secure performance of the facility. The protocol encompasses safety and security measures for protection from ionizing radiation of the individuals who work at the facility, as well as, the population and the environment in the immediate neighborhood of the facility. Thus, the adopted approach is the establishment of appropriate systems responding to the protocol. Dosimetry system, which includes appropriate procedures for accurate measure and recording of the absorbed dose values, according to the provisions for protection from ionizing radiation. Ionizing radiation protection system and providing the safety and security of the facility for food processing by means of ionizing radiation. System for providing quality and safety control of the facility for food processing by means of ionizing radiation. Pursuant to the designed a protocol for safe and secure performance of the facility for electron beam food processing, contributes to protection against ionizing radiation as occupationally exposed persons as well the population. (Author)

  10. Defocusing beam line design for an irradiation facility at the TAEA SANAEM Proton Accelerator Facility

    CERN Document Server

    Gencer, A.; Efthymiopoulos, I.; Yiğitoğlu, M.

    2016-01-01

    Electronic components must be tested to ensure reliable performance in high radiation environments such as Hi-Limu LHC and space. We propose a defocusing beam line to perform proton irradiation tests in Turkey. The Turkish Atomic Energy Authority SANAEM Proton Accelerator Facility was inaugurated in May 2012 for radioisotope production. The facility has also an R&D room for research purposes. The accelerator produces protons with 30 MeV kinetic energy and the beam current is variable between View the MathML source10μA and View the MathML source1.2mA. The beam kinetic energy is suitable for irradiation tests, however the beam current is high and therefore the flux must be lowered. We plan to build a defocusing beam line (DBL) in order to enlarge the beam size, reduce the flux to match the required specifications for the irradiation tests. Current design includes the beam transport and the final focusing magnets to blow up the beam. Scattering foils and a collimator is placed for the reduction of the beam ...

  11. Advanced ion beam calorimetry for the test facility ELISE

    International Nuclear Information System (INIS)

    Nocentini, R.; Fantz, U.; Franzen, P.; Fröschle, M.; Heinemann, B.; Riedl, R.; Ruf, B.; Wünderlich, D.; Bonomo, F.; Pimazzoni, A.; Pasqualotto, R.

    2015-01-01

    The negative ion source test facility ELISE (Extraction from a Large Ion Source Experiment) is in operation since beginning of 2013 at the Max-Planck-Institut für Plasmaphysik (IPP) in Garching bei München. The large radio frequency driven ion source of ELISE is about 1×1 m 2 in size (1/2 the ITER source) and can produce a plasma for up to 1 h. Negative ions can be extracted and accelerated by an ITER-like extraction system made of 3 grids with an area of 0.1 m 2 , for 10 s every 3 minutes. A total accelerating voltage of up to 60 kV is available, i.e. a maximum ion beam power of about 1.2 MW can be produced. ELISE is equipped with several beam diagnostic tools for the evaluation of the beam characteristics. In order to evaluate the beam properties with a high level of detail, a sophisticated diagnostic calorimeter has been installed in the test facility at the end of 2013, starting operation in January 2014. The diagnostic calorimeter is split into 4 copper plates with separate water calorimetry for each of the plates. Each calorimeter plate is made of 15×15 copper blocks, which act as many separate inertial calorimeters and are attached to a copper plate with an embedded cooling circuit. The block geometry and the connection with the cooling plate are optimized to accurately measure the time-averaged power of the 10 s ion beam. The surface of the blocks is covered with a black coating that allows infrared (IR) thermography which provides a 2D profile of the beam power density. In order to calibrate the IR thermography, 48 thermocouples are installed in as many blocks, arranged in two vertical and two horizontal rows. The paper describes the beam calorimetry in ELISE, including the methods used for the IR thermography, the water calorimetry and the analytical methods for beam profile evaluation. It is shown how the maximum beam inhomogeneity amounts to 13% in average. The beam divergence derived by IR thermography ranges between 1° and 4° and

  12. Neutron measurements from beam-target reactions at the ELISE neutral beam test facility

    International Nuclear Information System (INIS)

    Xufei, X.; Fan, T.; Nocente, M.; Gorini, G.; Bonomo, F.; Franzen, P.; Fröschle, M.; Grosso, G.; Tardocchi, M.; Grünauer, F.; Pasqualotto, R.

    2014-01-01

    Measurements of 2.5 MeV neutron emission from beam-target reactions performed at the ELISE neutral beam test facility are presented in this paper. The measurements are used to study the penetration of a deuterium beam in a copper dump, based on the observation of the time evolution of the neutron counting rate from beam-target reactions with a liquid scintillation detector. A calculation based on a local mixing model of deuterium deposition in the target up to a concentration of 20% at saturation is used to evaluate the expected neutron yield for comparison with data. The results are of relevance to understand neutron emission associated to beam penetration in a solid target, with applications to diagnostic systems for the SPIDER and MITICA Neutral Beam Injection prototypes

  13. The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy

    CERN Document Server

    Parodi, K; Cerutti, F; Ferrari, A; Mairani, A; Paganetti, H; Sommerer, F

    2010-01-01

    Monte Carlo (MC) methods are increasingly being utilized to support several aspects of commissioning and clinical operation of ion beam therapy facilities. In this contribution two emerging areas of MC applications are outlined. The value of MC modeling to promote accurate treatment planning is addressed via examples of application of the FLUKA code to proton and carbon ion therapy at the Heidelberg Ion Beam Therapy Center in Heidelberg, Germany, and at the Proton Therapy Center of Massachusetts General Hospital (MGH) Boston, USA. These include generation of basic data for input into the treatment planning system (TPS) and validation of the TPS analytical pencil-beam dose computations. Moreover, we review the implementation of PET/CT (Positron-Emission-Tomography / Computed- Tomography) imaging for in-vivo verification of proton therapy at MGH. Here, MC is used to calculate irradiation-induced positron-emitter production in tissue for comparison with the +-activity measurement in order to infer indirect infor...

  14. Nuclear astrophysics at the Holifield Radioactive Ion Beam Facility

    International Nuclear Information System (INIS)

    Smith, M.S.

    1994-01-01

    The potential for understanding spectacular stellar explosions such as novae, supernovae, and X-ray bursts will be greatly enhanced by the availability of the low-energy, high-intensity, accelerated beams of proton-rich radioactive nuclei currently being developed at the Holifield Radioactive Ion Beam Facility (HRIBF) at Oak Ridge National Laboratory. These beams will be utilized in absolute cross section measurements of crucial (p, γ) capture reactions in efforts to resolve the substantial qualitative uncertainties in current models of explosive stellar hydrogen burning outbursts. Details of the nuclear astrophysics research program with the unique HRIBF radioactive beams and a dedicated experimental endstation--centered on the Daresbury Recoil Separator--will be presented

  15. Neutron beam facilities at the replacement research reactor

    International Nuclear Information System (INIS)

    Kennedy, S.

    1999-01-01

    Full text: On September 3rd 1997 the Australian Federal Government announced their decision to replace the HIFAR research reactor by 2005. The proposed reactor will be a multipurpose reactor with improved capabilities for neutron beam research and for the production of radioisotopes for pharmaceutical, scientific and industrial use. The neutron beam facilities are intended to cater for Australian scientific needs well into the 21st century. In the first stage of planning the neutron Beam Facilities at the replacement reactor, a Consultative Group was formed (BFCG) to determine the scientific capabilities of the new facility. Members of the group were drawn from academia, industry and government research laboratories. The BFCG submitted their report in April 1998, outlining the scientific priorities to be addressed. Cold and hot neutron sources are to be included, and cold and thermal neutron guides will be used to position most of the instruments in a neutron guide hall outside the reactor confinement building. In 2005 it is planned to have eight instruments installed with a further three to be developed by 2010, and seven spare instrument positions for development of new instruments over the life of the reactor. A beam facilities technical group (BFTG) was then formed to prepare the engineering specifications for the tendering process. The group consisted of some members of the BFCG, several scientists and engineers from ANSTO, and scientists from leading neutron scattering centres in Europe, USA and Japan. The BFTG looked in detail at the key components of the facility such as the thermal, cold and hot neutron sources, neutron collimators, neutron beam guides and overall requirements for the neutron guide hall. The report of the BFTG, completed in August 1998, was incorporated into the draft specifications for the reactor project, which were distributed to potential reactor vendors. An assessment of the first stage of reactor vendor submissions was completed in

  16. Progress in neutron beam development at the HFR Petten (feasibility study for a BNCT facility)

    International Nuclear Information System (INIS)

    Constantine, G.; Moss, R.L.; Watkins, P.R.D.; Perks, C.A.; Delafield, H.J.; Ross, D.; Voorbraak, W.P.; Paardekooper, A.; Freudenreich, W.E.; Stecher-Rasmussen, F.

    1990-08-01

    Boron Neutron Capture Therapy, using intermediate energy neutrons to achieve the deep penetration essential for treating brain tumours, can be implemented with a filtered reactor neutron beam. This is designed to minimize the mean energy of the neutrons to keep proton recoil damage to the scalp within normal tissue tolerance limits whilst delivering the required thermal neutron fluence to the tumour over a reasonably short period. This can only be realized in conjunction with a high power density reactor. At the Joint Research Centre Petten an optimized neutron filter is currently being built for installation into the HB11 beam tube of the High Flux Reactor HFR. Part of the development leading to this design has been an extensive study of broad spectrum, filtered beam performance on the HB7 beam tube facility. A wide range of calculations was performed using the Monte Carlo code, MCPN, supported by validation experiments in which several filter configuration incorporating aluminium, sulphur, liquid argon, titanium and cadmium were installed for low power measurements of the neutron fluence rate, neutron spectra and beam gamma-ray contamination. The measurements were carried out within a successful European collaboration. Evaluations were made of the reactor core edge and unfiltered beam spectra, for comparison with MCNP calculations. Multi-foil activation methods and also gamma dose determination in the filtered beam using thermo-luminescent detectors were performed by the ECN. The Harwell/ Birmingham University collaborators undertook the neutron spectrum measurements in the filtered beam. proton recoil spectrometry was used above 30 keV, combined with a multi-sphere and BF 3 chamber response modification technique. Subsequent spectrum adjustment was carried out with the SENSAK code. The agreement between the calculated and measured spectra has given confidence in the reactor and filter modelling methods used to design the HB11 therapy facility. (author). 12 refs

  17. Wire Scanner Beam Profile Measurements for the LANSCE Facility

    Energy Technology Data Exchange (ETDEWEB)

    Gilpatrick, John D. [Los Alamos National Laboratory; Gruchalla, Michael E. [Los Alamos National Laboratory; Martinez, Derwin [Los Alamos National Laboratory; Pillai, Chandra [Los Alamos National Laboratory; Rodriguez Esparza, Sergio [Los Alamos National Laboratory; Sedillo, James Daniel [Los Alamos National Laboratory; Smith, Brian G. [Los Alamos National Laboratory

    2012-05-15

    The Los Alamos Neutron Science Center (LANSCE) is replacing beam profile measurement systems, commonly known as Wire Scanners (WS). Using the principal of secondary electron emission, the WS measurement system moves a wire or fiber across an impinging particle beam, sampling a projected transverse-beam distribution. Because existing WS actuators and electronic components are either no longer manufactured or home-built with antiquated parts, a new WS beam profile measurement is being designed, fabricated, and tested. The goals for these new WS's include using off-the-shelf components while eliminating antiquated components, providing quick operation while allowing for easy maintainability, and tolerating external radioactivation. The WS measurement system consists of beam line actuators, a cable plant, an electronics processor chassis, and software located both in the electronics chassis (National Instruments LabVIEW) and in the Central Control Room (EPICS-based client software). This WS measurement system will measure Hand H{sup +} LANSCE-facility beams and will also measure less common beams. This paper describes these WS measurement systems.

  18. Wire Scanner Beam Profile Measurements for the LANSCE Facility

    International Nuclear Information System (INIS)

    Gilpatrick, John D.; Gruchalla, Michael E.; Martinez, Derwin; Pillai, Chandra; Rodriguez Esparza, Sergio; Sedillo, James Daniel; Smith, Brian G.

    2012-01-01

    The Los Alamos Neutron Science Center (LANSCE) is replacing beam profile measurement systems, commonly known as Wire Scanners (WS). Using the principal of secondary electron emission, the WS measurement system moves a wire or fiber across an impinging particle beam, sampling a projected transverse-beam distribution. Because existing WS actuators and electronic components are either no longer manufactured or home-built with antiquated parts, a new WS beam profile measurement is being designed, fabricated, and tested. The goals for these new WS's include using off-the-shelf components while eliminating antiquated components, providing quick operation while allowing for easy maintainability, and tolerating external radioactivation. The WS measurement system consists of beam line actuators, a cable plant, an electronics processor chassis, and software located both in the electronics chassis (National Instruments LabVIEW) and in the Central Control Room (EPICS-based client software). This WS measurement system will measure Hand H + LANSCE-facility beams and will also measure less common beams. This paper describes these WS measurement systems.

  19. Broad-beam, high current, metal ion implantation facility

    International Nuclear Information System (INIS)

    Brown, I.G.; Dickinson, M.R.; Galvin, J.E.; Godechot, X.; MacGill, R.A.

    1990-07-01

    We have developed a high current metal ion implantation facility with which high current beams of virtually all the solid metals of the Periodic Table can be produced. The facility makes use of a metal vapor vacuum arc ion source which is operated in a pulsed mode, with pulse width 0.25 ms and repetition rate up to 100 pps. Beam extraction voltage is up to 100 kV, corresponding to an ion energy of up to several hundred keV because of the ion charge state multiplicity; beam current is up to several Amperes peak and around 10 mA time averaged delivered onto target. Implantation is done in a broad-beam mode, with a direct line-of-sight from ion source to target. Here we describe the facility and some of the implants that have been carried out using it, including the 'seeding' of silicon wafers prior to CVD with titanium, palladium or tungsten, the formation of buried iridium silicide layers, and actinide (uranium and thorium) doping of III-V compounds. 16 refs., 6 figs

  20. Beam tests on a proton linac booster for hadron therapy

    CERN Document Server

    De Martinis, C; Berra, P; Birattari, C; Calabretta, L; Crandall, K; Giove, D; Masullo, M R; Mauri, M; Rosso, E; Rovelli, A; Serafini, L; Szeless, Balázs; Toet, D Z; Vaccaro, Vittorio G; Weiss, M; Zennaro, R

    2002-01-01

    LIBO is a 3 GHz modular side-coupled proton linac booster designed to deliver beam energies up to 200 MeV, as required for the therapy of deep seated tumours. The injected beam of 50 to 70 MeV is produced by a cyclotron like those in several hospitals and research institutes. A full-scale prototype of the first module with an input/output energy of 62/74 MeV, respectively, was designed and built in 1999 and 2000. Full power RF tests were carried out successfully at CERN using a test facility at LIL at the end of the year 2000. In order to prove the feasibility of the acceleration process, an experimental setup with this module was installed at the INFN Laboratorio Nazionale del Sud (LNS) in Catania during 2001. The superconducting cyclotron provided the 62 MeV test beam. A compact solid-state RF modulator with a 4 MW klystron, made available by IBA-Scanditronix, was put into operation to power the linac. In this paper the main features of the accelerator are reviewed and the experimental results obtained duri...

  1. A beam monitor based on MPGD detectors for hadron therapy

    Directory of Open Access Journals (Sweden)

    Altieri P. R.

    2018-01-01

    Full Text Available Remarkable scientific and technological progress during the last years has led to the construction of accelerator based facilities dedicated to hadron therapy. This kind of technology requires precise and continuous control of position, intensity and shape of the ions or protons used to irradiate cancers. Patient safety, accelerator operation and dose delivery should be optimized by a real time monitoring of beam intensity and profile during the treatment, by using non-destructive, high spatial resolution detectors. In the framework of AMIDERHA (AMIDERHA - Enhanced Radiotherapy with HAdron project funded by the Ministero dell’Istruzione, dell’Università e della Ricerca (Italian Ministry of Education and Research the authors are studying and developing an innovative beam monitor based on Micro Pattern Gaseous Detectors (MPDGs characterized by a high spatial resolution and rate capability. The Monte Carlo simulation of the beam monitor prototype was carried out to optimize the geometrical set up and to predict the behavior of the detector. A first prototype has been constructed and successfully tested using 55Fe, 90Sr and also an X-ray tube. Preliminary results on both simulations and tests will be presented.

  2. CEBAF [Continuous Electron Beam Accelerator Facility] design report

    International Nuclear Information System (INIS)

    1986-05-01

    This book describes the conceptual design of, and the planning for, the Continuous Electron Beam Accelerator Facility (CEBAF), which will be a high-intensity, continuous-wave electron linear accelerator (linac) for nuclear physics. Its principal scientific goal is to understand the quark structure, behavior, and clustering of individual nucleons in the nuclear medium, and simultaneously to understand the forces governing this behavior. The linac will consist of 1 GeV of accelerating structure, split into two antiparallel 0.5-GeV segments. The segments will be connected by a beam transport system to circulate the electron beams from one segment to the other for up to four complete passes of acceleration. The maximum beam energy will be 4 GeV at a design current of 200 microamperes. The accelerator complex will also include systems to extract three continuous beams from the linac and to deliver them to three experimental halls equipped with detectors and instrumentation for nuclear physics research. The accelerating structure will be kept superconducting within insulated cryostats filled with liquid helium produced at a central helium refrigerator and distributed to the cryostats via insulated transfer lines. An injector, instrumentation and controls for the accelerator, radio-frequency power systems, and several support facilities will also be provided. A cost estimate based on the Work Breakdown Structure has been completed. Assuming a five-year construction schedule starting early in FY 1987, the total estimated cost is $236 million (actual year dollars), including contingency

  3. External beam radiation therapy for prostate cancer

    International Nuclear Information System (INIS)

    Forman, Jeffrey D.

    1996-01-01

    Purpose/Objectives: The intent of this course is to review the issues involved in the management of non-metastatic adenocarcinoma of the prostate. -- The value of pre-treatment prognostic factors including stage, grade and PSA value will be presented, and their value in determining therapeutic strategies will be discussed. -- Controversies involving the simulation process and treatment design will be presented. The value of CT scanning, Beams-Eye View, 3-D planning, intravesicle, intraurethral and rectal contrast will be presented. The significance of prostate and patient movement and strategies for dealing with them will be presented. -- The management of low stage, low to intermediate grade prostate cancer will be discussed. The dose, volume and timing of irradiation will be discussed as will the role of neo-adjuvant hormonal therapy, neutron irradiation and brachytherapy. The current status of radical prostatectomy and cryotherapy will be summarized. Treatment of locally advanced, poorly differentiated prostate cancer will be presented including a discussion of neo-adjuvant and adjuvant hormones, dose-escalation and neutron irradiation. -- Strategies for post-radiation failures will be presented including data on cryotherapy, salvage prostatectomy and hormonal therapy (immediate, delayed and/or intermittent). New areas for investigation will be reviewed. -- The management of patients post prostatectomy will be reviewed. Data on adjuvant radiation and therapeutic radiation for biochemical or clinically relapsed patients will be presented. This course hopes to present a realistic and pragmatic overview for treating patients with non-metastatic prostatic cancer

  4. Development and Commissioning of an External Beam Facility in the Union College Ion Beam Analysis Laboratory

    Science.gov (United States)

    Yoskowitz, Joshua; Clark, Morgan; Labrake, Scott; Vineyard, Michael

    2015-10-01

    We have developed an external beam facility for the 1.1-MV tandem Pelletron accelerator in the Union College Ion Beam Analysis Laboratory. The beam is extracted from an aluminum pipe through a 1 / 4 ' ' diameter window with a 7.5- μm thick Kapton foil. This external beam facility allows us to perform ion beam analysis on samples that cannot be put under vacuum, including wet samples and samples too large to fit into the scattering chamber. We have commissioned the new facility by performing proton induced X-ray emission (PIXE) analysis of several samples of environmental interest. These include samples of artificial turf, running tracks, and a human tooth with an amalgam filling. A 1.7-MeV external proton beam was incident on the samples positioned 2 cm from the window. The resulting X-rays were measured using a silicon drift detector and were analyzed using GUPIX software to determine the concentrations of elements in the samples. The results on the human tooth indicate that while significant concentrations of Hg, Ag, and Sn are present in the amalgam filling, only trace amounts of Hg appear to have leached into the tooth. The artificial turf and running tracks show rather large concentrations of a broad range of elements and trace amounts of Pb in the turf infill.

  5. Proposal for an intense slow positron beam facility at PSI

    International Nuclear Information System (INIS)

    Waeber, W.B.; Taqqu, D.; Zimmermann, U.; Solt, G.

    1990-05-01

    In the domain of condensed matter physics and materials sciences monoenergetic slow positrons in the form of highest intensity beams are demonstrated to be extreamly useful and considered to be highly needed. This conclusion has been reached and the scientific relevance of the positron probe has been highlighted at an international workshop in November 1989 at PSI, where the state of the art and the international situation on slow positron beams, the fields of application of intense beams and the technical possibilities at PSI for installing intense positron sources have been evaluated. The participants agreed that a high intensity beam as a large-scale user facility at PSI would serve fundamental and applied research. The analysis of responses given by numerous members of a widespread positron community has revealed a large research potential in the domain of solid-state physics, atomic physics and surface, thin-film and defect physics, for example. The excellent feature of slow positron beams to be a suitable probe also for lattice defects near surfaces or interfaces has attracted the interest not only of science but also of industry.In this report we propose the installation of an intense slow positron beam facility at PSI including various beam lines of different qualities and based on the Cyclotron production of β + emitting source material and on a highest efficiency moderation scheme which exceeds standard moderation efficiencies by two orders of magnitude. In its proposed form, the project is estimated to be realizable in the nineties and costs will amount to between 15 and 20 MSFr. (author) 10 figs., 6 tabs., 78 refs

  6. Beam Diagnostics for the BNL Energy Recovery Linac Test Facility

    International Nuclear Information System (INIS)

    Cameron, Peter; Ben-Zvi, Ilan; Blaskiewicz, Michael; Brennan, Michael; Connolly, Roger; Dawson, William; Degen, Chris; DellaPenna, Al; Gassner, David; Kesselman, Martin; Kewish, Jorg; Litvinenko, Vladimir; Mead, Joseph; Oerter, Brian; Russo, Tom; Vetter, Kurt; Yakimenko, Vitaly

    2004-01-01

    An Energy Recovery Linac (ERL) test facility is presently under construction at BNL. The goals of this test facility are first to demonstrate stable intense CW electron beam with parameters typical for the RHIC e-cooling project (and potentially for eRHIC), second to test novel elements of the ERL (high current CW photo-cathode, superconducting RF cavity with HOM dampers, and feedback systems), and finally to test lattice dependence of stability criteria. Planned diagnostics include position monitors, loss monitors, transverse profile monitors (both optical and wires), scrapers/halo monitors, a high resolution differential current monitor, phase monitors, an energy spread monitor, and a fast transverse monitor (for beam break-up studies and the energy feedback system). We discuss diagnostics challenges that are unique to this project, and present preliminary system specifications. In addition, we include a brief discussion of the timing system

  7. Beam Position Monitoring in the CSU Accelerator Facility

    Science.gov (United States)

    Einstein, Joshua; Vankeuren, Max; Watras, Stephen

    2014-03-01

    A Beam Position Monitoring (BPM) system is an integral part of an accelerator beamline, and modern accelerators can take advantage of newer technologies and designs when creating a BPM system. The Colorado State University (CSU) Accelerator Facility will include four stripline detectors mounted around the beamline, a low-noise analog front-end, and digitization and interface circuitry. The design will support a sampling rate greater than 10 Hz and sub-100 μm accuracy.

  8. CEBAF [Continuous Electron Beam Accelerator Facility] scientific program

    International Nuclear Information System (INIS)

    Gross, F.

    1986-01-01

    The principal scientific mission of the Continuous Electron Beam Facility (CEBAF) is to study collective phenomena in cold (or normal) nucler matter in order to understand the structure and behavior of macroscopic systems constructed from nuclei. This document discusses in broad popular terms those issues which the CEBAF experimental and theoretical program are designed to address. Specific experimental programs currently planned for CEBAF are also reivewed. 35 refs., 19 figs

  9. Testing optimization sequence for the beam port facility of PSBR

    International Nuclear Information System (INIS)

    Bekar, K.B.; Azmy, Y.Y.; Unlu, K.

    2005-01-01

    We present preliminary testing results of the modular code package prepared for the size and shape optimization of the beam tube device of the beam port facility at the Penn State Breazeale Reactor (PSBR). In the test cases, using the Min-max algorithm as an optimizer and multidimensional, neutral particle transport code TORT as a transport solver in the physics calculation, we optimize the shape of the D 2 O moderator of the beam tube device. We illustrate the modular nature of the optimization package, validation tests of the physics model, and preliminary optimization calculation via the whole code package. Results obtained so far indicate the drum-shaped D 2 O moderator tank is over-designed in size and does not possess the almost hemi-spherical optimal shape computed by our new package. (authors)

  10. Moving strip technique of electron beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Matsushima, Kishio; Wakasa, Hiroyuki; Oguri, Nobuhiro; Kitayama, Takuichi; Nakagiri, Yoshitada; Mikami, Yasutaka; Hashimoto, Keiji; Hiraki, Yoshio; Aono, Kaname

    1984-12-01

    The fieldsize in electron beam therapy is determined by the cone size. In case of skin metastasis of a malignant tumor and so on, which need a large field size and whose area is much larger than the size of the cone, a large field size is usually produced by dividing the portals. However, the dose distribution at the border of the field becomes unequal, and hot and cold dose areas are produced according to the distance between portals. We tried the strip field technique in a large field along the long axis of the body in order to flatten the dose of the border employing the moving strip used for whole abdominal irradiation in ovarian cancer. We set the film in Mix-DP and used the strip field technique with 2.5cm steps. We discussed the relationship between the interval (distance between portals) and the flattening of the dose within the field. Skin movement due to breathing and influences on the flattening of the dose were considered. The proper flatness was obtained at depths of 0,1,2, and 3cm by setting the interval at 0.5cm. When skin movement was produced by breathing in +-1.5mm, the proper flaness was obtained also at a 0.5-cm interval. It seems that smoothing is increased by breathing. An ''electron beam moving strip'' with a 2.5-cm step and 0.5-cm interval was clinically effective in the treatment of patients with skin metastasis of colon cancer. (author).

  11. Beam Diagnostics Systems for the National Ignition Facility

    International Nuclear Information System (INIS)

    Demaret, R D; Boyd, R D; Bliss, E S; Gates, A J; Severyn, J R

    2001-01-01

    The National Ignition Facility (NIF) laser focuses 1.8 megajoules of ultraviolet light (wavelength 351 nanometers) from 192 beams into a 600-micrometer-diameter volume. Effective use of this output in target experiments requires that the power output from all of the beams match within 8% over their entire 20-nanosecond waveform. The scope of NIF beam diagnostics systems necessary to accomplish this task is unprecedented for laser facilities. Each beamline contains 110 major optical components distributed over a 510-meter path, and diagnostic tolerances for beam measurement are demanding. Total laser pulse energy is measured with 2.8% precision, and the interbeam temporal variation of pulse power is measured with 4% precision. These measurement goals are achieved through use of approximately 160 sensor packages that measure the energy at five locations and power at three locations along each beamline using 335 photodiodes, 215 calorimeters, and 36 digitizers. Successful operation of such a system requires a high level of automation of the widely distributed sensors. Computer control systems provide the basis for operating the shot diagnostics with repeatable accuracy, assisted by operators who oversee system activities and setup, respond to performance exceptions, and complete calibration and maintenance tasks

  12. The ITER Neutral Beam Test Facility towards SPIDER operation

    Science.gov (United States)

    Toigo, V.; Dal Bello, S.; Gaio, E.; Luchetta, A.; Pasqualotto, R.; Zaccaria, P.; Bigi, M.; Chitarin, G.; Marcuzzi, D.; Pomaro, N.; Serianni, G.; Agostinetti, P.; Agostini, M.; Antoni, V.; Aprile, D.; Baltador, C.; Barbisan, M.; Battistella, M.; Boldrin, M.; Brombin, M.; Dalla Palma, M.; De Lorenzi, A.; Delogu, R.; De Muri, M.; Fellin, F.; Ferro, A.; Gambetta, G.; Grando, L.; Jain, P.; Maistrello, A.; Manduchi, G.; Marconato, N.; Pavei, M.; Peruzzo, S.; Pilan, N.; Pimazzoni, A.; Piovan, R.; Recchia, M.; Rizzolo, A.; Sartori, E.; Siragusa, M.; Spada, E.; Spagnolo, S.; Spolaore, M.; Taliercio, C.; Valente, M.; Veltri, P.; Zamengo, A.; Zaniol, B.; Zanotto, L.; Zaupa, M.; Boilson, D.; Graceffa, J.; Svensson, L.; Schunke, B.; Decamps, H.; Urbani, M.; Kushwah, M.; Chareyre, J.; Singh, M.; Bonicelli, T.; Agarici, G.; Garbuglia, A.; Masiello, A.; Paolucci, F.; Simon, M.; Bailly-Maitre, L.; Bragulat, E.; Gomez, G.; Gutierrez, D.; Mico, G.; Moreno, J.-F.; Pilard, V.; Chakraborty, A.; Baruah, U.; Rotti, C.; Patel, H.; Nagaraju, M. V.; Singh, N. P.; Patel, A.; Dhola, H.; Raval, B.; Fantz, U.; Fröschle, M.; Heinemann, B.; Kraus, W.; Nocentini, R.; Riedl, R.; Schiesko, L.; Wimmer, C.; Wünderlich, D.; Cavenago, M.; Croci, G.; Gorini, G.; Rebai, M.; Muraro, A.; Tardocchi, M.; Hemsworth, R.

    2017-08-01

    SPIDER is one of two projects of the ITER Neutral Beam Test Facility under construction in Padova, Italy, at the Consorzio RFX premises. It will have a 100 keV beam source with a full-size prototype of the radiofrequency ion source for the ITER neutral beam injector (NBI) and also, similar to the ITER diagnostic neutral beam, it is designed to operate with a pulse length of up to 3600 s, featuring an ITER-like magnetic filter field configuration (for high extraction of negative ions) and caesium oven (for high production of negative ions) layout as well as a wide set of diagnostics. These features will allow a reproduction of the ion source operation in ITER, which cannot be done in any other existing test facility. SPIDER realization is well advanced and the first operation is expected at the beginning of 2018, with the mission of achieving the ITER heating and diagnostic NBI ion source requirements and of improving its performance in terms of reliability and availability. This paper mainly focuses on the preparation of the first SPIDER operations—integration and testing of SPIDER components, completion and implementation of diagnostics and control and formulation of operation and research plan, based on a staged strategy.

  13. An irradiation facility with a horizontal beam for radiobiological studies

    International Nuclear Information System (INIS)

    Czub, J.; Adamus, T.; Banas, D.

    2006-01-01

    A facility with a horizontal beam for radiobiological experiments with heavy ions has been designed and constructed at the Heavy Ion Laboratory in Warsaw University. The facility is optimal to investigate the radiobiological effects of charged heavy particles on a cellular or molecular level as the plateau of the Bragg curve as well as in the Bragg peak. The passive beam spread out by a thin scattering foil provides a homogeneous irradiation field over an area of at least 1 x 1 cm 2 . For in vitro irradiation of biological samples the passive beam spreading combined with the x - y mechanical scanning of the irradiated sample was found to be an optimum solution. Using x - y step motor, the homogenous beam of ions with the energy loss range in the cells varied from 1 MeV/μm to 200 keV/μm is able to cover a 6 cm in diameter Petri dish that holds the biological samples. Moreover on-line fluence monitoring based on single-particle counting is performed to determine the dose absorbed by cells. Data acquisition system for dosimetry and ion monitoring based on a personal computer is described. (author)

  14. Neutron beam facilities at the Australian Replacement Research Reactor

    International Nuclear Information System (INIS)

    Kennedy, Shane; Robinson, Robert; Hunter, Brett

    2001-01-01

    Australia is building a research reactor to replace the HIFAR reactor at Lucas Heights by the end of 2005. Like HIFAR, the Replacement Research Reactor will be multipurpose with capabilities for both neutron beam research and radioisotope production. It will be a pool-type reactor with thermal neutron flux (unperturbed) of 4 x 10 14 n/cm 2 /sec and a liquid D 2 cold neutron source. Cold and thermal neutron beams for neutron beam research will be provided at the reactor face and in a large neutron guide hall. Supermirror neutron guides will transport cold and thermal neutrons to the guide hall. The reactor and the associated infrastructure, with the exception of the neutron beam instruments, is to be built by INVAP S.E. under contract. The neutron beam instruments will be developed by ANSTO, in consultation with the Australian user community. This status report includes a review the planned scientific capabilities, a description of the facility and a summary of progress to date. (author)

  15. Nanoscale insights into ion-beam cancer therapy

    CERN Document Server

    2017-01-01

    This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide. The book describes phenomena occurring on different time and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential ...

  16. Synchrotron accelerator technology for proton beam therapy with high accuracy

    International Nuclear Information System (INIS)

    Hiramoto, Kazuo

    2009-01-01

    Proton beam therapy was applied at the beginning to head and neck cancers, but it is now extended to prostate, lung and liver cancers. Thus the need for a pencil beam scanning method is increasing. With this method radiation dose concentration property of the proton beam will be further intensified. Hitachi group has supplied a pencil beam scanning therapy system as the first one for M. D. Anderson Hospital in United States, and it has been operational since May 2008. Hitachi group has been developing proton therapy system to correspond high-accuracy proton therapy to concentrate the dose in the diseased part which is located with various depths, and which sometimes has complicated shape. The author described here on the synchrotron accelerator technology that is an important element for constituting the proton therapy system. (K.Y.)

  17. Superconducting ring magnets of the PIOTRON Pi-meson therapy facility at SIN

    Energy Technology Data Exchange (ETDEWEB)

    Maix, R K; Meyer, G; Roman, T; Horvath, I; Vecsey, G; Zellweger, J

    1982-01-01

    Negative Pi-mesons seem to be very promising for cancer therapy, because of their well defined penetration depth and their enhanced energy deposition in the absorption region. A prototype Pi-meson therapy facility, called PIOTRON, has been constructed at SIN, where also pion beams of sufficient intensity are available. The central part of this system are two ring magnets, consisting each of 60 superconducting flat coils, with the aid of which 60 pion beams can be guided around a heavy iron shield and focused on the patient. In this paper the fabrication and the initial operation of these magnets is discussed.

  18. EPICS - MDSplus integration in the ITER Neutral Beam Test Facility

    International Nuclear Information System (INIS)

    Luchetta, Adriano; Manduchi, Gabriele; Barbalace, Antonio; Soppelsa, Anton; Taliercio, Cesare

    2011-01-01

    SPIDER, the ITER-size ion-source test bed in the ITER Neutral Beam Test Facility, is a fusion device requiring a complex central system to provide control and data acquisition, referred to as CODAS. The CODAS software architecture will rely on EPICS and MDSplus, two open-source, collaborative software frameworks, targeted at control and data acquisition, respectively. EPICS has been selected as ITER CODAC middleware and, as the final deliverable of the Neutral Beam Test Facility is the procurement of the ITER Heating Neutral Beam Injector, we decided to adopt this ITER technology. MDSplus is a software package for data management, supporting advanced concepts, such as platform and underlying hardware independence, self description data, and data driven model. The combined use of EPICS and MDSplus is not new in fusion, but their level of integration will be new in SPIDER, achieved by a more refined data access layer. The paper presents the integration software to use effectively EPICS and MDSplus, including the definition of appropriate EPICS records to interact with MDSplus. The MDSplus and EPICS archive concepts are also compared on the basis of performance tests and data streaming is investigated by ad-hoc measurements.

  19. Dosimetry auditing procedure with alanine dosimeters for light ion beam therapy

    DEFF Research Database (Denmark)

    Ableitinger, Alexander; Vatnitsky, Stanislav; Herrmann, Rochus

    2013-01-01

    Background and purpose In the next few years the number of facilities providing ion beam therapy with scanning beams will increase. An auditing process based on an end-to-end test (including CT imaging, planning and dose delivery) could help new ion therapy centres to validate their entire logistic...... of the biological dose is out of scope of the current work. Materials and methods The audit procedure was based on a homogeneous phantom that mimics the dimension of a head (20 × 20 × 21 cm3). The phantom can be loaded either with an ionisation chamber or 20 alanine dosimeters plus 2 radiochromic EBT films. Dose...... fluence in the alanine detector. A pilot run was performed with protons and carbon ions at the Heidelberg Ion Therapy facility (HIT). Results The mean difference of the absolute physical dose measured with the alanine dosimeters compared with the expected dose from the treatment planning system was −2...

  20. Measurement of secondary particle production induced by particle therapy ion beams impinging on a PMMA target

    Directory of Open Access Journals (Sweden)

    Toppi M.

    2016-01-01

    Full Text Available Particle therapy is a technique that uses accelerated charged ions for cancer treatment and combines a high irradiation precision with a high biological effectiveness in killing tumor cells [1]. Informations about the secondary particles emitted in the interaction of an ion beam with the patient during a treatment can be of great interest in order to monitor the dose deposition. For this purpose an experiment at the HIT (Heidelberg Ion-Beam Therapy Center beam facility has been performed in order to measure fluxes and emission profiles of secondary particles produced in the interaction of therapeutic beams with a PMMA target. In this contribution some preliminary results about the emission profiles and the energy spectra of the detected secondaries will be presented.

  1. The synchrotron and its related technology for ion beam therapy

    International Nuclear Information System (INIS)

    Hiramoto, Kazuo; Umezawa, Masumi; Saito, Kazuyoshi; Tootake, Satoshi; Nishiuchi, Hideaki; Hara, Shigemistu; Tanaka, Masanobu; Matsuda, Koji; Sakurabata, Hiroaki; Moriyama, Kunio

    2007-01-01

    Hitachi has developed several new technologies for the synchrotron and its related system to realize reliable and flexible operation of a proton therapy system. Especially important among them are a non-resonant RF acceleration cavity using FINEMET core with multiple power feeding and radio frequency driven beam extraction technique (RF-DE) for a synchrotron. Various treatment operations such as variable acceleration energy or respiration gating became possible and simple due to the above technique. For beam transport, a beam steering method for the beam, using transfer matrix realizes quick and precise correction of the beam orbit. A compact microwave ion source has also been developed for the injector to obtain further higher reliability and availability. Most of these technologies are also effective to enhance the reliability and flexibility of other ion beam therapy systems

  2. Beam based alignment at the KEK accelerator test facility

    International Nuclear Information System (INIS)

    Ross, M.; Nelson, J.; Woodley, M.; Wolski, A.

    2002-01-01

    The KEK Accelerator Test Facility (ATF) damping ring is a prototype low emittance source for the NLC/JLC linear collider. To achieve the goal normalized vertical emittance gey = 20 nm-rad, magnet placement accuracy better than 30 mm must be achieved. Accurate beam-based alignment (BBA) is required. The ATF arc optics uses a FOBO cell with two horizontally focusing quadrupoles, two sextupoles and a horizontally defocusing gradient dipole, all of which must be aligned with BBA. BBA at ATF uses the quadrupole and sextupole trim windings to find the trajectory through the center of each magnet. The results can be interpreted to assess the accuracy of the mechanical alignment and the beam position monitor offsets

  3. Radiotherapy for ocular lesions by electron beam therapy

    International Nuclear Information System (INIS)

    Miyaishi, Kazuo

    1981-01-01

    Radiotherapy can be very significant as the treatment for ocular lesions, eyes need to be preserved as properly as possible on their functions and cosmetics. The appliance of conventional X ray therapy has been gradually abandaned as conventional X ray therapy ceased to be accepted as the general treatment for malignant tumors. Consequently the necessity of electron beam therapy has been rising even as the substituted method for conventional X ray therapy. The department of radiology of Gunma University was obliged to establish a new therapy for ocular lesions, and has been trying electron beam therapy since 1973; It is concluded that electron beam therapy is not at all inferior to conventional X ray therapy as reported above. Basic therapeutic methods for ocular lesions are the following: 1) For epidermoid carcinoma, 600 rads at a time, 3600 - 4200 rads in total is applied by 8 MeV electron twice a week method. 2) For malignant melanoma, 1000 rads at a time, 4000 - 5000 rads in total is applied by 8 MeV electron twice a week method. 3) For orbitar lymphoid neoplasm, Cobalt-60 γ ray or Linac X ray is applied together with electron beam. 4) For embryonal rhabdomyosarcoma, adenoid cystic cancer etc., the therapy for whole body is necessary. 5) For benign tumors, a small dose at a time is applied for a long time. (author)

  4. Neutron capture therapy beams at the MIT Research Reactor

    International Nuclear Information System (INIS)

    Choi, J.R.; Clement, S.D.; Harling, O.K.; Zamenhof, R.G.

    1990-01-01

    Several neutron beams that could be used for neutron capture therapy at MITR-II are dosimetrically characterized and their suitability for the treatment of glioblastoma multiforme and other types of tumors are described. The types of neutron beams studied are: (1) those filtered by various thicknesses of cadmium, D2O, 6Li, and bismuth; and (2) epithermal beams achieved by filtration with aluminum, sulfur, cadmium, 6Li, and bismuth. Measured dose vs. depth data are presented in polyethylene phantom with references to what can be expected in brain. The results indicate that both types of neutron beams are useful for neutron capture therapy. The first type of neutron beams have good therapeutic advantage depths (approximately 5 cm) and excellent in-phantom ratios of therapeutic dose to background dose. Such beams would be useful for treating tumors located at relatively shallow depths in the brain. On the other hand, the second type of neutron beams have superior therapeutic advantage depths (greater than 6 cm) and good in-phantom therapeutic advantage ratios. Such beams, when used along with bilateral irradiation schemes, would be able to treat tumors at any depth in the brain. Numerical examples of what could be achieved with these beams, using RBEs, fractionated-dose delivery, unilateral, and bilateral irradiation are presented in the paper. Finally, additional plans for further neutron beam development at MITR-II are discussed

  5. Proton beam therapy and accountable care: the challenges ahead.

    Science.gov (United States)

    Elnahal, Shereef M; Kerstiens, John; Helsper, Richard S; Zietman, Anthony L; Johnstone, Peter A S

    2013-03-15

    Proton beam therapy (PBT) centers have drawn increasing public scrutiny for their high cost. The behavior of such facilities is likely to change under the Affordable Care Act. We modeled how accountable care reform may affect the financial standing of PBT centers and their incentives to treat complex patient cases. We used operational data and publicly listed Medicare rates to model the relationship between financial metrics for PBT center performance and case mix (defined as the percentage of complex cases, such as pediatric central nervous system tumors). Financial metrics included total daily revenues and debt coverage (daily revenues - daily debt payments). Fee-for-service (FFS) and accountable care (ACO) reimbursement scenarios were modeled. Sensitivity analyses were performed around the room time required to treat noncomplex cases: simple (30 minutes), prostate (24 minutes), and short prostate (15 minutes). Sensitivity analyses were also performed for total machine operating time (14, 16, and 18 h/d). Reimbursement under ACOs could reduce daily revenues in PBT centers by up to 32%. The incremental revenue gained by replacing 1 complex case with noncomplex cases was lowest for simple cases and highest for short prostate cases. ACO rates reduced this incremental incentive by 53.2% for simple cases and 41.7% for short prostate cases. To cover daily debt payments after ACO rates were imposed, 26% fewer complex patients were allowable at varying capital costs and interest rates. Only facilities with total machine operating times of 18 hours per day would cover debt payments in all scenarios. Debt-financed PBT centers will face steep challenges to remain financially viable after ACO implementation. Paradoxically, reduced reimbursement for noncomplex cases will require PBT centers to treat more such cases over cases for which PBT has demonstrated superior outcomes. Relative losses will be highest for those facilities focused primarily on treating noncomplex cases

  6. Proton Beam Therapy and Accountable Care: The Challenges Ahead

    International Nuclear Information System (INIS)

    Elnahal, Shereef M.; Kerstiens, John; Helsper, Richard S.; Zietman, Anthony L.; Johnstone, Peter A.S.

    2013-01-01

    Purpose: Proton beam therapy (PBT) centers have drawn increasing public scrutiny for their high cost. The behavior of such facilities is likely to change under the Affordable Care Act. We modeled how accountable care reform may affect the financial standing of PBT centers and their incentives to treat complex patient cases. Methods and Materials: We used operational data and publicly listed Medicare rates to model the relationship between financial metrics for PBT center performance and case mix (defined as the percentage of complex cases, such as pediatric central nervous system tumors). Financial metrics included total daily revenues and debt coverage (daily revenues − daily debt payments). Fee-for-service (FFS) and accountable care (ACO) reimbursement scenarios were modeled. Sensitivity analyses were performed around the room time required to treat noncomplex cases: simple (30 minutes), prostate (24 minutes), and short prostate (15 minutes). Sensitivity analyses were also performed for total machine operating time (14, 16, and 18 h/d). Results: Reimbursement under ACOs could reduce daily revenues in PBT centers by up to 32%. The incremental revenue gained by replacing 1 complex case with noncomplex cases was lowest for simple cases and highest for short prostate cases. ACO rates reduced this incremental incentive by 53.2% for simple cases and 41.7% for short prostate cases. To cover daily debt payments after ACO rates were imposed, 26% fewer complex patients were allowable at varying capital costs and interest rates. Only facilities with total machine operating times of 18 hours per day would cover debt payments in all scenarios. Conclusions: Debt-financed PBT centers will face steep challenges to remain financially viable after ACO implementation. Paradoxically, reduced reimbursement for noncomplex cases will require PBT centers to treat more such cases over cases for which PBT has demonstrated superior outcomes. Relative losses will be highest for those

  7. Proton Beam Therapy and Accountable Care: The Challenges Ahead

    Energy Technology Data Exchange (ETDEWEB)

    Elnahal, Shereef M., E-mail: selnahal@partners.org [Department of Medicine, Brigham and Women' s Hospital, Boston, MA (United States); Kerstiens, John [Proton Therapy Center, Indiana University, Bloomington, IN (United States); Helsper, Richard S. [Genesis HealthCare System, Zanesville, OH (United States); Zietman, Anthony L. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA (United States); Johnstone, Peter A.S. [Proton Therapy Center, Indiana University, Bloomington, IN (United States); Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN (United States)

    2013-03-15

    Purpose: Proton beam therapy (PBT) centers have drawn increasing public scrutiny for their high cost. The behavior of such facilities is likely to change under the Affordable Care Act. We modeled how accountable care reform may affect the financial standing of PBT centers and their incentives to treat complex patient cases. Methods and Materials: We used operational data and publicly listed Medicare rates to model the relationship between financial metrics for PBT center performance and case mix (defined as the percentage of complex cases, such as pediatric central nervous system tumors). Financial metrics included total daily revenues and debt coverage (daily revenues − daily debt payments). Fee-for-service (FFS) and accountable care (ACO) reimbursement scenarios were modeled. Sensitivity analyses were performed around the room time required to treat noncomplex cases: simple (30 minutes), prostate (24 minutes), and short prostate (15 minutes). Sensitivity analyses were also performed for total machine operating time (14, 16, and 18 h/d). Results: Reimbursement under ACOs could reduce daily revenues in PBT centers by up to 32%. The incremental revenue gained by replacing 1 complex case with noncomplex cases was lowest for simple cases and highest for short prostate cases. ACO rates reduced this incremental incentive by 53.2% for simple cases and 41.7% for short prostate cases. To cover daily debt payments after ACO rates were imposed, 26% fewer complex patients were allowable at varying capital costs and interest rates. Only facilities with total machine operating times of 18 hours per day would cover debt payments in all scenarios. Conclusions: Debt-financed PBT centers will face steep challenges to remain financially viable after ACO implementation. Paradoxically, reduced reimbursement for noncomplex cases will require PBT centers to treat more such cases over cases for which PBT has demonstrated superior outcomes. Relative losses will be highest for those

  8. A proton beam delivery system for conformal therapy and intensity modulated therapy

    International Nuclear Information System (INIS)

    Yu Qingchang

    2001-01-01

    A scattering proton beam delivery system for conformal therapy and intensity modulated therapy is described. The beam is laterally spread out by a dual-ring double scattering system and collimated by a program-controlled multileaf collimator and patient specific fixed collimators. The proton range is adjusted and modulated by a program controlled binary filter and ridge filters

  9. Beam Phase Detection for Proton Therapy Accelerators

    CERN Document Server

    Aminov, Bachtior; Getta, Markus; Kolesov, Sergej; Pupeter, Nico; Stephani, Thomas; Timmer, J

    2005-01-01

    The industrial application of proton cyclotrons for medical applications has become one of the important contributions of accelerator physics during the last years. This paper describes an advanced vector demodulating technique used for non-destructive measurements of beam intensity and beam phase over 360°. A computer controlled I/Q-based phase detector with a very large dynamic range of 70 dB permits the monitoring of beam intensity, phase and eventually energy for wide range of beam currents down to -130 dBm. In order to avoid interference from the fundamental cyclotron frequency the phase detection is performed at the second harmonic frequency. A digital low pass filter with adjustable bandwidth and steepness is implemented to improve accuracy. With a sensitivity of the capacitive pickup in the beam line of 30 nV per nA of proton beam current at 250 MeV, accurate phase and intensity measurements can be performed with beam currents down to 3.3 nA.

  10. Anesthesia for pediatric external beam radiation therapy

    International Nuclear Information System (INIS)

    Fortney, Jennifer T.; Halperin, Edward C.; Hertz, Caryn M.; Schulman, Scott R.

    1999-01-01

    Background: For very young patients, anesthesia is often required for radiotherapy. This results in multiple exposures to anesthetic agents over a short period of time. We report a consecutive series of children anesthetized for external beam radiation therapy (EBRT). Methods: Five hundred twelve children ≤ 16 years old received EBRT from January 1983 to February 1996. Patient demographics, diagnosis, anesthesia techniques, monitoring, airway management, complications, and outcome were recorded for the patients requiring anesthesia. Results: One hundred twenty-three of the 512 children (24%) required 141 courses of EBRT with anesthesia. Anesthetized patients ranged in age from 20 days to 11 years (mean 2.6 ± 1.8 ). The frequency of a child receiving EBRT and requiring anesthesia by age cohort was: ≤ 1 year (96%), 1-2 years (93%), 2-3 years (80%), 3-4 years (51%), 4-5 years (36%), 5-6 years (13%), 6-7 years (11%), and 7-16 years (0.7%). Diagnoses included: primary CNS tumor (28%), retinoblastoma (27%), neuroblastoma (20%), acute leukemia (9%), rhabdomyosarcoma (6%), and Wilms' tumor (4%). Sixty-three percent of the patients had been exposed to chemotherapy prior to EBRT. The mean number of anesthesia sessions per patient was 22 ± 16. Seventy-eight percent of the treatment courses were once daily and 22% were twice daily. Anesthesia techniques included: short-acting barbiturate induction + inhalation maintenance (21%), inhalation only (20%), ketamine (19%), propofol only (12%), propofol induction + inhalation maintenance (7%), ketamine induction + inhalation maintenance (6%), ketamine or short-acting barbiturate induction + inhalation maintenance (6%). Monitoring techniques included: EKG (95%), O 2 saturation (93%), fraction of inspired O 2 (57%), and end-tidal CO 2 (55%). Sixty-four percent of patients had central venous access. Eleven of the 74 children with a central line developed sepsis (15%): 6 of the 11 were anesthetized with propofol (55%), 4 with a

  11. Progress report of the innovated KIST ion beam facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Joonkon; Eliades, John A.; Yu, Byung-Yong; Lim, Weon Cheol; Chae, Keun Hwa; Song, Jonghan, E-mail: jonghansong@gmail.com

    2017-01-15

    The Korea Institute of Science and Technology (KIST, Seoul, Republic of (S.) Korea) ion beam facility consists of three electrostatic accelerators: a 400 kV single ended ion implanter, a 2 MV tandem accelerator system and a 6 MV tandem accelerator system. The 400 kV and 6 MV systems were purchased from High Voltage Engineering Europa (HVEE, Netherlands) and commissioned in 2013, while the 2 MV system was purchased from National Electrostatics Corporation (NEC, USA) in 1995. These systems are used to provide traditional ion beam analysis (IBA), isotope ratio analysis (ex. accelerator mass spectrometry, AMS), and ion implantation/irradiation for domestic industrial and academic users. The main facility is the 6 MV HVEE Tandetron system that has an AMS line currently used for {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36} Cl, {sup 41}Ca and {sup 129}I analyses, and three lines for IBA that are under construction. Here, these systems are introduced with their specifications and initial performance results.

  12. Biological basis of heavy ion beams for cancer therapy

    International Nuclear Information System (INIS)

    Sakamoto, Kiyohiko

    1985-01-01

    Fast neutron therapy has started firstly and proton therapy has commenced secondly, fast neutron shows better biological effects compared to conventional radiations but its dose distribution is not good, and proton demonstrates excellent dose distribution but its biological effects are almost the same as that of conventional radiations. On the other hand, negative pi-mesons and heavy ions indicate high radiobiological effect and excellent dose distribution, therefore these particle radiations is considered to be more attractive for radiotherapeutic radiations to enhance cure rate of cancers. The biological strong points of these particles are as follows : 1) cells exposed to these particle radiations shows less recovery after irradiation compared to conventional radiations, 2) these radiations show high biological effects (high value of relative biological effectiveness = RBE) when the same dose is given, 3) big effects on hypoxic cells which exsist in tumor, i.e. the value of oxygen enhancement ratio (OER) is low, 4) the differences in radiosensitivity by stages of cell cycle are not so great (data was not shown in present paper), 5) biological effects at prepeak plateau region in depth dose curve formed by these particle radiations is less than that at peak region (therefore, if beam is modulated to cover tumor at spraed out broad peak, tumors is given more biological effect compared to normal tissues which is to be exposed to radiations at prepaeak region). Clinical trial using heavy ions are being performed at Lawrence Berkeley Laboratory which is only one facility to be able to try clinical trial. The results of clinical trials at Lawrence Berkeley Laboratory suggest to be very prospective to enhance tumor cure rate, however it is too early to estimate the effect of heavy ion therapy. (J.P.N.)

  13. Beam-optics study of the gantry beam delivery system for light-ion cancer therapy

    International Nuclear Information System (INIS)

    Pavlovic, M.

    1995-12-01

    Ion optics considerations on the granty-like beam delivery system for light-ion cancer therapy are presented. A low-angle active beam scanning in two directions is included in the preliminary gantry design. The optical properties of several gantry modifications are discussed. (orig.)

  14. Investigation of plasma–surface interaction at plasma beam facilities

    Energy Technology Data Exchange (ETDEWEB)

    Kurnaev, V., E-mail: kurnaev@plasma.mephi.ru [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Kashirskoe sh. 31, 115409 Moscow (Russian Federation); Vizgalov, I.; Gutorov, K. [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Kashirskoe sh. 31, 115409 Moscow (Russian Federation); Tulenbergenov, T.; Sokolov, I.; Kolodeshnikov, A.; Ignashev, V.; Zuev, V.; Bogomolova, I. [Institute of Atomic Energy, National Nuclear Center the Republic of Kazakhstan, Street Krasnoarmejsky, 10, 071100 Kurchatov (Kazakhstan); Klimov, N. [SRC RF TRINITI, ul. Pushkovykh, vladenie 12, Troitsk, 142190 Moscow (Russian Federation)

    2015-08-15

    The new Plasma Beam Facility (PBF) has been put into operation for assistance in testing of plasma faced components at Material Science Kazakhstan Tokamak (KTM). PBF includes a powerful electron gun (up to 30 kV, 1 A) and a high vacuum chamber with longitudinal magnetic field coils (up to 0.2 T). The regime of high vacuum electron beam transportation is used for thermal tests with power density at the target surface up to 10 GW/m{sup 2}. The beam plasma discharge (BPD) regime with a gas-puff is used for generation of intensive ion fluxes up to 3 ⋅ 10{sup 22} m{sup −2} s{sup −1}. Initial tests of the KTM PBF’s capabilities were carried out: various discharge regimes, carbon deposits cleaning, simultaneous thermal and ion impacts on radiation cooled refractory targets. With a water-cooled target the KTM PBF could be used for high heat flux tests of materials (validated by the experiment with W mock-up at the PR-2 PBF)

  15. Environmental assessment: Continuous Electron Beam Accelerator Facility, Newport News, Virginia

    International Nuclear Information System (INIS)

    1987-01-01

    This Environmental Assessment has been prepared by the US Department of Energy (DOE) to fulfill its obligations pursuant to Sect. 102 of the National Environmental Policy Act (NEPA) of 1969 (Public Law 91-190). The proposed federal action addressed in this document is DOE's funding of a Continuous Electron Beam Accelerator Facility (CEBAF) at Newport News, Virginia. DOE intends to contract with the Southeastern Universities Research Association (SURA) for operation of CEBAF, a continuous wave (CW) linear accelerator system (linac) capable of providing high-duty-factor beams throughout the energy range from 0.5 to 4.0 GeV. CEBAF will be the first of its kind worldwide and will offer a multi-GeV energy, high-intensity, high-duty-factor electron beam for use by the US nuclear physics community in research on the states of nuclear matter and the short-distance behavior of nuclei. The CEBAF project is largely in the conceptual design stage, with some components in the preliminary design stage. Construction is anticipated to begin in 1987 and be completed by 1992

  16. Development of the RRR cold neutron beam facility

    International Nuclear Information System (INIS)

    Lovotti, Osvaldo; Masriera, Nestor; Lecot, Carlos; Hergenreder, Daniel

    2002-01-01

    This paper describes some general design issues on the neutron beam facilities (cold neutron source and neutron beam transport system) of the Replacement Research Reactor (RRR) for the Australian Nuclear Science and Technology Organisation (ANSTO). The description covers different aspect of the design: the requirements that lead to an innovative design, the overall design itself, the definition of a technical approach in order to develop the necessary design solutions, and finally the organizational framework by which international expertise from five different institutions is integrated. From the technical viewpoint, the RRR-CNS is a liquid Deuterium (LD2) moderator, sub-cooled to ensure maximum moderation efficiency, flowing within a closed natural circulation thermosyphon loop. The thermosyphon is surrounded by a zirconium alloy CNS vacuum containment that provides thermal insulation and a multiple barriers scheme to prevent Deuterium from mixing with water or air. Consistent with international practice, this vessel is designed to withstand any hypothetical energy reaction should Deuterium and air mix in its interior. The 'cold' neutrons are then taken by the NBTS and transported by the neutron guide system into the reactor beam hall and neutron guide hall, where neutron scattering instruments are located. From the management viewpoint, the adopted distributed scheme is successful to manage the complex interfacing between highly specialized technologies, allowing a smooth integration within the project. (author)

  17. Maintenance schemes for the ITER neutral beam test facility

    International Nuclear Information System (INIS)

    Zaccaria, P.; Dal Bello, S.; Marcuzzi, D.; Masiello, A.; Coniglio, A.; Antoni, V.; Cordier, J.J.; Hemsworth, R.; Jones, T.; Di Pietro, E.; Mondino, P.L.

    2004-01-01

    The ITER neutral beam test facility (NBTF) is planned to be built, after the approval of the ITER construction and the choice of the ITER site, with the agreement of the ITER International Team and of the JA and RF participant teams. The key purpose is to progressively increase the performance of the first ITER injector and to demonstrate its reliability at the maximum operation parameters: power delivered to the plasma 16.5 MW, beam energy 1 MeV, accelerated D - ion current 40 A, pulse length 3600 s. Several interventions for possible modifications and for maintenance are expected during the early operation of the ITER injector in order to optimize the beam generation, aiming and steering. The maintenance scheme and the related design solutions are therefore a very important aspect to be considered for the NBTF design. The paper describes consistently the many interrelated aspects of the design, such as the optimisation of the vessel and cryopump geometry, in order to get a better maintenance flexibility, an easier man access and a larger access for diagnostic and monitoring. (authors)

  18. Ion spectroscopy for improvement of the physical beam model for therapy planning in ion beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Arico, Giulia

    2016-11-23

    Helium and carbon ions enable a more conformal dose distribution, narrower penumbra and higher relative biological effectiveness than photon and proton radiotherapy. However, they may undergo nuclear fragmentation in the patient tissues and the arising secondary fragments affect the delivered biological dose distributions. Currently there is a lack of data regarding ion nuclear fragmentation. One reason is the large size (up to some meters) of the experimental setups required for the investigations. In this thesis a new method is presented, which makes use of versatile pixelated semiconductor detectors (Timepix). This method is based on tracking of single particles and pattern recognition of their signals in the detectors. Measurements were performed at the HIT facility. The mixed radiation field arising from 430 MeV/u carbon ion beams and 221 MeV/u helium ion beams in water and in PMMA targets was investigated. The amounts of primary (carbon or helium) ions detected behind targets with the same water equivalent thickness (WET) were found to be in agreement within the statistical uncertainties. However, more fragments (differences up to 20% in case of H) and narrower lateral particle distributions were measured behind the PMMA than the water targets. The spectra of ions behind tissue surrogates and corresponding water targets with the same WET were analysed. The results obtained with adipose and inner bone surrogates and with the equivalent water phantoms were found to be consistent within the uncertainties. Significant differences in the results were observed in the case of lung and cortical bone surrogates when compared to the water phantoms. The experimental results were compared to FLUKA Monte Carlo simulations. This comparison could contribute to enhance the ion interaction models currently implemented for {sup 12}C and {sup 4}He ion beams.

  19. Preliminary investigations of Monte Carlo Simulations of neutron energy and LET spectra for fast neutron therapy facilities

    International Nuclear Information System (INIS)

    Kroc, T.K.

    2009-01-01

    No fast neutron therapy facility has been built with optimized beam quality based on a thorough understanding of the neutron spectrum and its resulting biological effectiveness. A study has been initiated to provide the information necessary for such an optimization. Monte Carlo studies will be used to simulate neutron energy spectra and LET spectra. These studies will be bench-marked with data taken at existing fast neutron therapy facilities. Results will also be compared with radiobiological studies to further support beam quality ptimization. These simulations, anchored by this data, will then be used to determine what parameters might be optimized to take full advantage of the unique LET properties of fast neutron beams. This paper will present preliminary work in generating energy and LET spectra for the Fermilab fast neutron therapy facility.

  20. Development of beam instruments at JAERI cyclotron facility

    Energy Technology Data Exchange (ETDEWEB)

    Okumura, Susumu; Fukuda, Mitsuhiro; Ishibori, Ikuo; Agematsu, Takashi; Yokota, Watalu; Nara, Takayuki; Nakamura, Yoshiteru; Arakawa, Kazuo [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    A beam phase monitor and two kinds of fluence distribution monitors have been developed for measuring characteristics of cyclotron beams. The beam phase monitor provides a beam phase signal for tuning a beam chopping system and a beam phase selection system. A two-dimensional fluence distribution on a large area is measured with fluence distribution monitors. (author)

  1. Measurements and simulations of focused beam for orthovoltage therapy

    International Nuclear Information System (INIS)

    Abbas, Hassan; Mahato, Dip N.; Satti, Jahangir; MacDonald, C. A.

    2014-01-01

    Purpose: Megavoltage photon beams are typically used for therapy because of their skin-sparing effect. However, a focused low-energy x-ray beam would also be skin sparing, and would have a higher dose concentration at the focal spot. Such a beam can be produced with polycapillary optics. MCNP5 was used to model dose profiles for a scanned focused beam, using measured beam parameters. The potential of low energy focused x-ray beams for radiation therapy was assessed. Methods: A polycapillary optic was used to focus the x-ray beam from a tungsten source. The optic was characterized and measurements were performed at 50 kV. PMMA blocks of varying thicknesses were placed between optic and the focal spot to observe any variation in the focusing of the beam after passing through the tissue-equivalent material. The measured energy spectrum was used to model the focused beam in MCNP5. A source card (SDEF) in MCNP5 was used to simulate the converging x-ray beam. Dose calculations were performed inside a breast tissue phantom. Results: The measured focal spot size for the polycapillary optic was 0.2 mm with a depth of field of 5 mm. The measured focal spot remained unchanged through 40 mm of phantom thickness. The calculated depth dose curve inside the breast tissue showed a dose peak several centimeters below the skin with a sharp dose fall off around the focus. The percent dose falls below 10% within 5 mm of the focus. It was shown that rotating the optic during scanning would preserve the skin-sparing effect of the focused beam. Conclusions: Low energy focused x-ray beams could be used to irradiate tumors inside soft tissue within 5 cm of the surface

  2. Status of the realization of the neutral beam test facility

    International Nuclear Information System (INIS)

    Toigo, Vanni

    2015-01-01

    The ITER Neutral Beam Injectors (NBI) are required to deliver 16.5 MW of additional heating power to the plasma, accelerating negative ions up to -1 MV with a beam current of 40A lasting up to 1 hour. Since these outstanding requirements were never achieved all together so far, the realization of a Neutral Beam Test Facility (NBTF), called PRIMA, currently under construction in Padova, was launched with the aim to test the operation of the NB injector and to study the relevant physical and technological issues, in advance to the implementation in ITER. Two projects are under development: MITICA and SPIDER. MITICA is a full scale prototype of the ITER NB injector; the design is based on a similar scheme and layout, with the same power supply system and also the control and protection systems are being designed according to the ITER rules and constraints. The HV components are procured by JADA; the low voltage ones and the injector are procured by F4E. SPIDER project is an ion source with the same characteristics of the ITER one, specifically addressed to study the issues related to the RF operation; for this reason, the beam energy is limited to 100keV. It can generate both Hydrogen and Deuterium Ions; the design includes provisions to filter electrons and also to allow the use of cesium to attain the high values of current density required. SPIDER is procured by F4E and INDA. The construction of PRIMA buildings and auxiliaries, started in autumn 2008, was completed in summer 2015. SPIDER plant systems procurement is well advanced and some systems are under installation or site acceptance tests. In 2016 integrated commissioning and power supply integrated tests will be performed followed by the beginning of the first experimental phase. MITICA design was completed; many procurement contracts have been signed or will be launched in the next months. Installation activity will start in December 2015 with the installation of the first HV power supply components provided

  3. Optimization of the irradiation beam in the BNCT research facility at IEA-R1 reactor

    International Nuclear Information System (INIS)

    Castro, Vinicius Alexandre de

    2014-01-01

    Boron Neutron Capture Therapy (BNCT) is a radiotherapeutic technique for the treatment of some types of cancer whose useful energy comes from a nuclear reaction that occurs when thermal neutron impinges upon a Boron-10 atom. In Brazil there is a research facility built along the beam hole number 3 of the IEA-R1 research reactor at IPEN, which was designed to perform BNCT research experiments. For a good performance of the technique, the irradiation beam should be mostly composed of thermal neutrons with a minimum as possible gamma and above thermal neutron components. This work aims to monitor and evaluate the irradiation beam on the sample irradiation position through the use of activation detectors (activation foils) and also to propose, through simulation using the radiation transport code, MCNP, new sets of moderators and filters which shall deliver better irradiation fields at the irradiation sample position In this work, a simulation methodology, based on a MCNP card, known as wwg (weight window generation) was studied, and the neutron energy spectrum has been experimentally discriminated at 5 energy ranges by using a new set o activation foils. It also has been concluded that the BNCT research facility has the required thermal neutron flux to perform studies in the area and it has a great potential for improvement for tailoring the irradiation field. (author)

  4. Study on external beam radiation therapy

    International Nuclear Information System (INIS)

    Kim, Mi Sook; Yoo, Seoung Yul; Yoo, Hyung Jun; Ji, Young Hoon; Lee, Dong Han; Lee, Dong Hoon; Choi, Mun Sik; Yoo, Dae Heon; Lee, Hyo Nam; Kim, Kyeoung Jung

    1999-04-01

    To develop the therapy technique which promote accuracy and convenience in external radiation therapy, to obtain the development of clinical treatment methods for the global competition. The contents of the R and D were 1. structure, process and outcome analysis in radiation therapy department. 2. Development of multimodality treatment in radiation therapy 3. Development of computation using networking techniques 4. Development of quality assurance (QA) system in radiation therapy 5. Development of radiotherapy tools 6. Development of intraoperative radiation therapy (IORT) tools. The results of the R and D were 1. completion of survey and analysis about Korea radiation therapy status 2. Performing QA analysis about ICR on cervix cancer 3. Trial of multicenter randomized study on lung cancers 4. Setting up inter-departmental LAN using MS NT server and Notes program 5. Development of ionization chamber and dose-rate meter for QA in linear accelerator 6. Development on optimized radiation distribution algorithm for multiple slice 7. Implementation on 3 dimensional volume surface algorithm and 8. Implementation on adaptor and cone for IORT

  5. Study on external beam radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mi Sook; Yoo, Seoung Yul; Yoo, Hyung Jun; Ji, Young Hoon; Lee, Dong Han; Lee, Dong Hoon; Choi, Mun Sik; Yoo, Dae Heon; Lee, Hyo Nam; Kim, Kyeoung Jung

    1999-04-01

    To develop the therapy technique which promote accuracy and convenience in external radiation therapy, to obtain the development of clinical treatment methods for the global competition. The contents of the R and D were 1. structure, process and outcome analysis in radiation therapy department. 2. Development of multimodality treatment in radiation therapy 3. Development of computation using networking techniques 4. Development of quality assurance (QA) system in radiation therapy 5. Development of radiotherapy tools 6. Development of intraoperative radiation therapy (IORT) tools. The results of the R and D were 1. completion of survey and analysis about Korea radiation therapy status 2. Performing QA analysis about ICR on cervix cancer 3. Trial of multicenter randomized study on lung cancers 4. Setting up inter-departmental LAN using MS NT server and Notes program 5. Development of ionization chamber and dose-rate meter for QA in linear accelerator 6. Development on optimized radiation distribution algorithm for multiple slice 7. Implementation on 3 dimensional volume surface algorithm and 8. Implementation on adaptor and cone for IORT.

  6. Radiation dermatitis following electron beam therapy

    International Nuclear Information System (INIS)

    Price, N.M.

    1978-01-01

    Ten patients, who had been treated for mycosis fungoides with electron beam radiation ten or more years previously, were examined for signs of radiation dermatitis. Although most patients had had acute radiation dermatitis, only a few manifested signs of mild chronic changes after having received between 1,000 and 2,800 rads

  7. Treatment Planning for Ion Beam Therapy

    Science.gov (United States)

    Jäkel, Oliver

    The special aspects of treatment planning for ion beams are outlined in this chapter, starting with positioning and immobilization of the patient, describing imaging and segmentation, definition of treatment parameters, dose calculation and optimization, and, finally, plan assessment, verification, and quality assurance.

  8. Multi-beam Mossbauer scattering facility. Final technical report

    International Nuclear Information System (INIS)

    1994-01-01

    The Mossbauer instrument construction which was financed by the DOE grant of $74,065 and MU matching funds of $52,000 is essentially completed and awaiting installation at the Missouri University Research Reactor (MURR) facility. All of the DOE funds have been spent and all of the matching funds plus about $4,000 to $5,000 of additional physics department funds have been committed to finishing the first phase of the new instrument, QUEGS--II (for QUAsiElastic Gamma-ray Scattering--generation II). This phase includes computer controls, detectors, and instrumentation for two of the four beam lines afforded by QUEGS-II. Included in this commitment of funds is $8,700 for equipment and machine shop services which have not yet been paid and $19,700 for a Ge detector for which bids are ready to be let

  9. Experimental support at proton--proton colliding beam facilities

    International Nuclear Information System (INIS)

    Potter, K.

    1977-01-01

    Proton--proton colliding beam facilities have a number of special features which increase the importance of support for experiments when compared to fixed target accelerators: (1) the laboratory system is very close to the center-of-mass system; this affects the geometry and general size of the experiments; (2) the primary p--p interaction is inaccessible, that is, it takes place in an ultrahigh vacuum chamber; and (3) the experiment detection system is necessarily inside the machine structure and becomes very closely linked to it in many respects. An overall picture is given of experimental support based on experience at the CERN ISR under the following headings: Experimental Areas, Scheduling, Intersection Vacuum Chambers, Machine Background, and Magnets for Experiments. The first two of these topics concern the requirements in space and time of an experiment, while the last three are all related to the close interaction between experiment and machine

  10. The radioactive ion beams facility project for the legnaro laboratories

    Science.gov (United States)

    Tecchio, Luigi B.

    1999-04-01

    In the frame work of the Italian participation to the project of a high intensity proton facility for the energy amplifier and nuclear waste transmutations, LNL is involving in the design and construction of prototypes of the injection system of the 1 GeV linac that consists of a RFQ (5 MeV, 30 mA) followed by a 100 MeV linac. This program has been already financially supported and the work is actually in progress. In this context, the LNL has been proposed a project for the construction of a second generation facility for the production of radioactive ion beams (RIBs) by using the ISOL method. The final goal consists in the production of neutron rich RIBs with masses ranging from 80 to 160 by using primary beams of protons, deuterons and light ions with energy of 100 MeV and 100 kW power. This project is proposed to be developed in about 10 years from now and intermediate milestones and experiments are foreseen and under consideration for the next INFN five year plan (1999-2003). In such period of time is proposed the construction of a proton/deuteron accelerator of 10 MeV energy and 10 mA current, consisting of a RFQ (5 MeV, 30 mA) and a linac (10 MeV, 10 mA), and of a neutron area dedicated to the RIBs production, to the BNCT applications and to the neutron physics. Some remarks on the production methods will be presented. The possibility of producing radioisotopes by means of the fission induced by neutrons will be investigated and the methods of production of neutrons will be discussed.

  11. High resolution muon computed tomography at neutrino beam facilities

    International Nuclear Information System (INIS)

    Suerfu, B.; Tully, C.G.

    2016-01-01

    X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we show via simulation that muon beams can provide high resolution tomographic images of dense objects and of structures within the interior of dense objects. The effects of resolution broadening from multiple scattering diminish with increasing muon momentum. As the momentum of the muon increases, the contrast of the image goes down and therefore requires higher resolution in the muon spectrometer to resolve the image. The variance of the measured muon momentum reaches a minimum and then increases with increasing muon momentum. The impact of the increase in variance is to require a higher integrated muon flux to reduce fluctuations. The flux requirements and level of contrast needed for high resolution muon computed tomography are well matched to the muons produced in the pion decay pipe at a neutrino beam facility and what can be achieved for momentum resolution in a muon spectrometer. Such an imaging system can be applied in archaeology, art history, engineering, material identification and whenever there is a need to image inside a transportable object constructed of dense materials

  12. A Study on the Ion Beam Extraction using Duo-PiGatron Ion source for Vertical Type Ion Beam Facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bom Sok; Lee, Chan young; Lee, Jae Sang [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    In Korea Multipurpose Accelerator Complex (KOMAC), we have started ion beam service in the new beam utilization building since March this year. For various ion beam irradiation services, we are developed implanters such as metal (150keV/1mA), gaseous (200keV/5mA) and high current ion beam facility (20keV/150mA). One of the new one is a vertical type ion beam facility without acceleration tube (60keV/20mA) which is easy to install the sample. After the installation is complete, it is where you are studying the optimal ion beam extraction process. Detailed experimental results will be presented. Vertical Type Ion Beam Facility without acceleration tube of 60keV 20mA class was installed. We successfully extracted 60keV 20mA using Duo- PiGatron Ion source for Vertical Type Ion Beam Facility. Use the BPM and Faraday-cup, is being studied the optimum conditions of ion beam extraction.

  13. Measurement of the tissue to A-150 tissue equivalent plastic kerma ratio at two p(66)Be neutron therapy facilities

    International Nuclear Information System (INIS)

    Langen, K M; Binns, P J; Schreuder, A N; Lennox, A J; Deluca, P M Jr.

    2003-01-01

    The ICRU tissue to A-150 tissue equivalent plastic kerma ratio is needed for neutron therapy dosimetry. The current ICRU protocol for neutron dosimetry recommends using a common conversion factor of 0.95 at all high-energy neutron therapy facilities. In an effort to determine facility specific ICRU tissue to A-150 plastic kerma ratios, an experimental approach was pursued. Four low pressure proportional counters that differed in wall materials (i.e. A-150, carbon, zirconium and zirconium-oxide) were used as dosimeters and integral kerma ratios were determined directly in the clinical beam. Measurements were performed at two p(66)Be facilities: iThemba LABS near Cape Town and Fermilab near Chicago. At the iThemba facility the clinical neutron beam is routinely filtered by a flattening and hardening filter combination. The influence of beam filtration on the kerma ratio was evaluated. Using two recent gas-to-wall dose conversion factor (r m,g value) evaluations a mean ICRU tissue to A-150 plastic kerma ratio of 0.93 ± 0.05 was determined for the clinical beam at iThemba LABS. The respective value for the Fermilab beam is 0.95 ± 0.05. The experimentally determined ICRU tissue to A-150 plastic kerma ratios for the two clinical beams are in agreement with theoretical evaluations. Beam filtration reduces the kerma ratio by 3 ± 2%

  14. Establishment of nuclear data system - Feasibility study for neutron-beam= facility at pohang accelerator laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Nam Kung, Won; Koh, In Soo; Cho, Moo Hyun; Kim, Kui Nyun; Kwang, Hung Sik; Park, Sung Joo [Pohang Accelerator Laboratory, Pohang (Korea, Republic of)

    1996-12-01

    Nuclear data which have been produced by a few developed countries in the= past are essential elements to many disciplines, especially to nuclear engineering. As we promote our nuclear industry further to the level of advanced countries, we also have to establish the Nuclear Data System to produce and evaluate nuclear data independently. We have studied the possibility to build a neutron-beam facility utilizing accelerator facilities, technologies and man powers at pohang Accelerator Laboratory. We found specific parameters for the PAL 100-MeV electron linac based on the existing klystron, modulator, accelerating tubes and other facilities in the PAL; the beam energy is 60-100 MeV, the beam current for the short pulse (10 ns) is 2 A and for the long pulse is 500 mA and the pulse repetition rate is 60 Hz. We propose a neutron-beam facility using PAL 100-MeV electron linac where we can use a Ta-target for the neutron generation and three different time-of-flight beam lines (10 m, 20 m, and 100 m). One may find that the proposed neutron-beam facility is comparable with other operating neutron facilities in the world. We conclude that the proposed neutron-beam facility utilizing the existing accelerator facility in the PAL would be an excellent facility for neutron data production in combination with the ` Hanaro` facility in KAERI. 8 refs., 11 tabs., 12 figs. (author)

  15. Metrology and quality of radiation therapy dosimetry of electron, photon and epithermal neutron beams

    Energy Technology Data Exchange (ETDEWEB)

    Kosunen, A

    1999-08-01

    In radiation therapy using electron and photon beams the dosimetry chain consists of several sequential phases starting by the realisation of the dose quantity in the Primary Standard Dosimetry Laboratory and ending to the calculation of the dose to a patient. A similar procedure can be described for the dosimetry of epithermal neutron beams in boron neutron capture therapy (BNCT). To achieve the required accuracy of the dose delivered to a patient the quality of all steps in the dosimetry procedure has to be considered. This work is focused on two items in the dosimetry chains: the determination of the dose in the reference conditions and the evaluation of the accuracy of dose calculation methods. The issues investigated and discussed in detail are: a)the calibration methods of plane parallel ionisation chambers used in electron beam dosimetry, (b) the specification of the critical dosimetric parameter i.e. the ratio of stopping powers for water to air, (S I ?){sup water} {sub air}, in photon beams, (c) the feasibility of the twin ionization chamber technique for dosimetry in epithermal neutron beams applied to BNCT and (d) the determination accuracy of the calculated dose distributions in phantoms in electron, photon, and epithermal neutron beams. The results demonstrate that up to a 3% improvement in the consistency of dose determinations in electron beams is achieved by the calibration of plane parallel ionisation chambers in high energy electron beams instead of calibrations in {sup 60}Co gamma beams. In photon beam dosimetry (S I ?){sup water} {sub air} can be determined with an accuracy of 0.2% using the percentage dose at the 10 cm depth, %dd(10), as a beam specifier. The use of %odd(10) requires the elimination of the electron contamination in the photon beam. By a twin ionisation chamber technique the gamma dose can be determined with uncertainty of 6% (1 standard deviation) and the total neutron dose with an uncertainty of 15 to 20% (1 standard deviation

  16. Metrology and quality of radiation therapy dosimetry of electron, photon and epithermal neutron beams

    International Nuclear Information System (INIS)

    Kosunen, A.

    1999-08-01

    In radiation therapy using electron and photon beams the dosimetry chain consists of several sequential phases starting by the realisation of the dose quantity in the Primary Standard Dosimetry Laboratory and ending to the calculation of the dose to a patient. A similar procedure can be described for the dosimetry of epithermal neutron beams in boron neutron capture therapy (BNCT). To achieve the required accuracy of the dose delivered to a patient the quality of all steps in the dosimetry procedure has to be considered. This work is focused on two items in the dosimetry chains: the determination of the dose in the reference conditions and the evaluation of the accuracy of dose calculation methods. The issues investigated and discussed in detail are: a)the calibration methods of plane parallel ionisation chambers used in electron beam dosimetry, (b) the specification of the critical dosimetric parameter i.e. the ratio of stopping powers for water to air, (S I ?) water air , in photon beams, (c) the feasibility of the twin ionization chamber technique for dosimetry in epithermal neutron beams applied to BNCT and (d) the determination accuracy of the calculated dose distributions in phantoms in electron, photon, and epithermal neutron beams. The results demonstrate that up to a 3% improvement in the consistency of dose determinations in electron beams is achieved by the calibration of plane parallel ionisation chambers in high energy electron beams instead of calibrations in 60 Co gamma beams. In photon beam dosimetry (S I ?) water air can be determined with an accuracy of 0.2% using the percentage dose at the 10 cm depth, %dd(10), as a beam specifier. The use of %odd(10) requires the elimination of the electron contamination in the photon beam. By a twin ionisation chamber technique the gamma dose can be determined with uncertainty of 6% (1 standard deviation) and the total neutron dose with an uncertainty of 15 to 20% (1 standard deviation). To improve the accuracy

  17. Therapy tumor with the heavy ions beam

    International Nuclear Information System (INIS)

    Dang Bingrong; Wei Zengquan; Li Wenjian

    2002-01-01

    As physical characteristic of heavy ions Bragg peak, therapy tumor with heavy ions is becoming advanced technology. So, many countries have developed the technology and used to treat tumor, the societal and economic effects are beneficial to people. The authors show the development, present situation and information of research in world of advanced radiotherapy with heavy ions

  18. A neutron beam facility for radioactive ion beams and other applications

    Science.gov (United States)

    Tecchio, L. B.

    1999-06-01

    In the framework of the Italian participation in the project of a high intensity proton facility for the energy amplifier and nuclear waste transmutations, LNL is involved in the design and construction of same prototypes of the injection system of the 1 GeV linac that consists of a RFQ (5 MeV, 30 mA) followed by a 100 MeV linac. This program has already been supported financially and the work is in progress. In this context LNL has proposed a project for the construction of a second generation facility for the production of radioactive ion beams (RIBs) by means of the ISOL method. The final goal is the production of neutron rich RIBs with masses ranging from 30 to 150 by using primary beams of protons, deuterons and light ions with energy of 100 MeV and 100 kW power. This project is expected to be developed in about 10 years from new and intermediate milestones and experiments are foreseen and under consideration for the next INFN five year plan (1999-2003). During that period the construction of a proton/deuteron accelerator of 10 MeV energy and 10 mA current, consisting of a RFQ (5 MeV, 30 mA) and a linac (10 MeV, 10 mA), and of a neutron area dedicated to the RIBs production and to the neutron physics, is proposed. Some remarks on the production methods will be presented. The possibility of producing radioisotopes by means of the fission induced by neutrons will be investigated and the methods of production of neutrons will be discussed. Besides the RIBs production, neutron beams for the BNCT applications and neutron physics are also planned.

  19. A GIF++ Gamma Irradiation Facility at the SPS H4 Beam Line

    CERN Document Server

    Capéans-Garrido, M; Linssen, L; Moll, M; Rembser, C

    2009-01-01

    The current document describes a proposal to implement a new gamma irradiation facility, combined with a high-energy particle beam in the SPS H4 beam line in hall EHN1. This new GIF++ facility is motivated by strong needs from the LHC and sLHC detector and accelerator communities for the tests of LHC components and systems.

  20. Experimental Program for the CLIC test facility 3 test beam line

    CERN Document Server

    Adli, E; Dobert, S; Olvegaard, M; Schulte, D; Syratchev, I; Lillestol, Reidar

    2010-01-01

    The CLIC Test Facility 3 Test Beam Line is the first prototype for the CLIC drive beam decelerator. Stable transport of the drive beam under deceleration is a mandatory component in the CLIC two-beam scheme. In the Test Beam Line more than 50% of the total energy will be extracted from a 150 MeV, 28 A electron drive beam, by the use of 16 power extraction and transfer structures. A number of experiments are foreseen to investigate the drive beam characteristics under deceleration in the Test Beam Line, including beam stability, beam blow up and the efficiency of the power extraction. General benchmarking of decelerator simulation and theory studies will also be performed. Specially designed instrumentation including precision BPMs, loss monitors and a time-resolved spectrometer dump will be used for the experiments. This paper describes the experimental program foreseen for the Test Beam Line, including the relevance of the results for the CLIC decelerator studies.

  1. Magnetically scanned proton therapy beams: rationales and techniques

    International Nuclear Information System (INIS)

    Jones, D.T.L.; Schreuder, A.N.

    2000-01-01

    Perhaps the most important advantages of beam scanning systems for proton therapy in comparison with conventional passive beam spreading systems are: (1) Intensity modulation and inverse planning are possible. (2) There is negligible reduction in the range of the beam. (3) Integral dose is reduced as dose conformation to the proximal edge of the lesion is possible. (4) In principle no field-specific modifying devices are required. (5) There is less activation of the surroundings. (6) Scanning systems axe almost infinitely flexible. The main disadvantages include: (1) Scanning systems are more complicated and therefore potentially less reliable and more dangerous. (2) The development of such systems is more demanding in terms of cost, time and manpower. (3) More stable beams are required. (4) Dose and beam position monitoring are more difficult. (5) The problems associated with patient and organ movement axe more severe. There are several techniques which can be used for scanning. For lateral beam spreading, circular scanning (wobbling) or linear scanning can be done. In the latter case the beam can be scanned continuously or in a discrete fashion (spot scanning). Another possibility is to undertake the fastest scan in one dimension (strip scanning) and translate the patient or the scanning magnet in the other dimension. Depth variation is achieved by interposing degraders in the beam (cyclotrons) or by changing the beam energy (synchrotrons). The aim of beam scanning is to deliver a predetermined dose at any point in the body. Special safety precautions must be taken because of the high instantaneous dose rates. The beam position and the dose delivered at each point must be accurately and redundantly determined. (author)

  2. Dosimetry of beams for negative pi-meson radiation therapy

    International Nuclear Information System (INIS)

    Dicello, J.F.

    1976-01-01

    Several new facilities have been built in the last few years which can produce high intensity beams of pions. As a result, a significant amount of new data related to pion dosimetry is available. Results of beam composition, beam shaping, and collimation are given along with depth dose curves and isodose contours. Experimental data which describe the radiation quality of pion beams and the change in radiation quality with position are presented. Experimental data determining the fraction of the dose resulting from neutrons are discussed. The present techniques used in pion dosimetry are summarized, and those areas of pion dosimetry which require additional effort in order to achieve routine treatment planning for patients are reviewed

  3. The GEANT4 toolkit capability in the hadron therapy field: simulation of a transport beam line

    International Nuclear Information System (INIS)

    Cirrone, G.A.P.; Cuttone, G.; Di Rosa, F.; Raffaele, L.; Russo, G.; Guatelli, S.; Pia, M.G.

    2006-01-01

    At Laboratori Nazionali del Sud of the Instituto Nazionale di Fisica Nucleare of Catania (Sicily, Italy), the first Italian hadron therapy facility named CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been realized. Inside CATANA 62 MeV proton beams, accelerated by a superconducting cyclotron, are used for the radiotherapeutic treatments of some types of ocular tumours. Therapy with hadron beams still represents a pioneer technique, and only a few centers worldwide can provide this advanced specialized cancer treatment. On the basis of the experience so far gained, and considering the future hadron-therapy facilities to be developed (Rinecker, Munich Germany, Heidelberg/GSI, Darmstadt, Germany, PSI Villigen, Switzerland, CNAO, Pavia, Italy, Centro di Adroterapia, Catania, Italy) we decided to develop a Monte Carlo application based on the GEANT4 toolkit, for the design, the realization and the optimization of a proton-therapy beam line. Another feature of our project is to provide a general tool able to study the interactions of hadrons with the human tissue and to test the analytical-based treatment planning systems actually used in the routine practice. All the typical elements of a hadron-therapy line, such as diffusers, range shifters, collimators and detectors were modelled. In particular, we simulated the Markus type ionization chamber and a Gaf Chromic film as dosimeters to reconstruct the depth (Bragg peak and Spread Out Bragg Peak) and lateral dose distributions, respectively. We validated our simulated detectors comparing the results with the experimental data available in our facility

  4. The GEANT4 toolkit capability in the hadron therapy field: simulation of a transport beam line

    Science.gov (United States)

    Cirrone, G. A. P.; Cuttone, G.; Di Rosa, F.; Raffaele, L.; Russo, G.; Guatelli, S.; Pia, M. G.

    2006-01-01

    At Laboratori Nazionali del Sud of the Instituto Nazionale di Fisica Nucleare of Catania (Sicily, Italy), the first Italian hadron therapy facility named CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been realized. Inside CATANA 62 MeV proton beams, accelerated by a superconducting cyclotron, are used for the radiotherapeutic treatments of some types of ocular tumours. Therapy with hadron beams still represents a pioneer technique, and only a few centers worldwide can provide this advanced specialized cancer treatment. On the basis of the experience so far gained, and considering the future hadron-therapy facilities to be developed (Rinecker, Munich Germany, Heidelberg/GSI, Darmstadt, Germany, PSI Villigen, Switzerland, CNAO, Pavia, Italy, Centro di Adroterapia, Catania, Italy) we decided to develop a Monte Carlo application based on the GEANT4 toolkit, for the design, the realization and the optimization of a proton-therapy beam line. Another feature of our project is to provide a general tool able to study the interactions of hadrons with the human tissue and to test the analytical-based treatment planning systems actually used in the routine practice. All the typical elements of a hadron-therapy line, such as diffusers, range shifters, collimators and detectors were modelled. In particular, we simulated the Markus type ionization chamber and a Gaf Chromic film as dosimeters to reconstruct the depth (Bragg peak and Spread Out Bragg Peak) and lateral dose distributions, respectively. We validated our simulated detectors comparing the results with the experimental data available in our facility.

  5. The GEANT4 toolkit capability in the hadron therapy field: simulation of a transport beam line

    Energy Technology Data Exchange (ETDEWEB)

    Cirrone, G.A.P. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Cuttone, G. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Di Rosa, F. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Raffaele, L. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Russo, G. [Laboratori Nazionali del Sud, Istituto Nazionale di Fisica Nucleare, Via S. Sofia 62, Catania (Italy); Guatelli, S. [Istituto Nazionale di Fisica Nucleare, Sezione di Genova, Via Dodecaneso 33, Genova (Italy); Pia, M.G. [Istituto Nazionale di Fisica Nucleare, Sezione di Genova, Via Dodecaneso 33, Genova (Italy)

    2006-01-15

    At Laboratori Nazionali del Sud of the Instituto Nazionale di Fisica Nucleare of Catania (Sicily, Italy), the first Italian hadron therapy facility named CATANA (Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been realized. Inside CATANA 62 MeV proton beams, accelerated by a superconducting cyclotron, are used for the radiotherapeutic treatments of some types of ocular tumours. Therapy with hadron beams still represents a pioneer technique, and only a few centers worldwide can provide this advanced specialized cancer treatment. On the basis of the experience so far gained, and considering the future hadron-therapy facilities to be developed (Rinecker, Munich Germany, Heidelberg/GSI, Darmstadt, Germany, PSI Villigen, Switzerland, CNAO, Pavia, Italy, Centro di Adroterapia, Catania, Italy) we decided to develop a Monte Carlo application based on the GEANT4 toolkit, for the design, the realization and the optimization of a proton-therapy beam line. Another feature of our project is to provide a general tool able to study the interactions of hadrons with the human tissue and to test the analytical-based treatment planning systems actually used in the routine practice. All the typical elements of a hadron-therapy line, such as diffusers, range shifters, collimators and detectors were modelled. In particular, we simulated the Markus type ionization chamber and a Gaf Chromic film as dosimeters to reconstruct the depth (Bragg peak and Spread Out Bragg Peak) and lateral dose distributions, respectively. We validated our simulated detectors comparing the results with the experimental data available in our facility.

  6. CEBAF [Continuous Electron Beam Accelerator Facility] design overview and project status

    International Nuclear Information System (INIS)

    Leemann, C.

    1988-01-01

    This paper discusses the design and specifications of the Continuous Electron Beam Accelerator Facility. Beam performance objectives are discussed, as well as the recirculating linac concept, the injector, cavities, cryogenic system, beam transport and optics, rf system and construction progress. 19 refs., 10 figs

  7. Clinical application of dosimetry in electron beam therapy

    International Nuclear Information System (INIS)

    Yoshiura, Takao

    1995-01-01

    In everyday radiotherapy we must carry out the determination of absorbed dose measurement according to JARP's protocol. We explained an outline of JARP's 1974 and 1986 protocol in electron beam therapy, and mentioned it about the matter that should examined. To use it easily in clinic, a simplified procedure based on precisely to JARP's 1986 protocol is practical, the character of this procedure settles briefly the determination of mean incident energy of electron beams and get ready to table of ionization to absorbed dose conversion factor for various ionization chamber. Also, this procedure almost not influence on the accuracy of determination. We described systematically practical procedure for requisite absorbed dose calculation in a patient in electron beam therapy. (author)

  8. A Monte Carlo code for ion beam therapy

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    Initially developed for applications in detector and accelerator physics, the modern Fluka Monte Carlo code is now used in many different areas of nuclear science. Over the last 25 years, the code has evolved to include new features, such as ion beam simulations. Given the growing use of these beams in cancer treatment, Fluka simulations are being used to design treatment plans in several hadron-therapy centres in Europe.   Fluka calculates the dose distribution for a patient treated at CNAO with proton beams. The colour-bar displays the normalized dose values. Fluka is a Monte Carlo code that very accurately simulates electromagnetic and nuclear interactions in matter. In the 1990s, in collaboration with NASA, the code was developed to predict potential radiation hazards received by space crews during possible future trips to Mars. Over the years, it has become the standard tool to investigate beam-machine interactions, radiation damage and radioprotection issues in the CERN accelerator com...

  9. The 50 MeV Beam Test Facility at LBL

    International Nuclear Information System (INIS)

    Leemans, W.; Behrsing, G.; Kim, K.J.; Krupnick, J.; Matuk, C.; Selph, F.; Chattopadhyay, S.

    1993-05-01

    A new beam line, expected to be built by September 1993, will transport the 50 MeV electron beam from the ALS LINAC into an experimental area to support various R ampersand D activities in the Center for Beam Physics at LBL. A variety of experiments are planned involving the interaction of such a relativistic electron beam with plasmas (plasma focusing), laser beams (generation of femtosecond X-ray pulses) and electromagnetic cavities (Crab cavities etc....). The beam line is designed using the measured emittance and Twiss parameters of the ALS linac. It accommodates the different requirements of the various experiments on the electron beam properties (charge, energy, pulse length) and on the handling of the beam before and after the interaction point. Special attention has also been given to incorporate diagnostics for measuring the beam properties (such as the electron energy, bunch length and charge) needed in the interpretation of the experiments

  10. Optimal Neutron Source and Beam Shaping Assembly for Boron Neutron Capture Therapy

    International Nuclear Information System (INIS)

    Vujic, J.; Greenspan, E.; Kastenber, W.E.; Karni, Y.; Regev, D.; Verbeke, J.M.; Leung, K.N.; Chivers, D.; Guess, S.; Kim, L.; Waldron, W.; Zhu, Y.

    2003-01-01

    There were three objectives to this project: (1) The development of the 2-D Swan code for the optimization of the nuclear design of facilities for medical applications of radiation, radiation shields, blankets of accelerator-driven systems, fusion facilities, etc. (2) Identification of the maximum beam quality that can be obtained for Boron Neutron Capture Therapy (BNCT) from different reactor-, and accelerator-based neutron sources. The optimal beam-shaping assembly (BSA) design for each neutron source was also to e obtained. (3) Feasibility assessment of a new neutron source for NCT and other medical and industrial applications. This source consists of a state-of-the-art proton or deuteron accelerator driving and inherently safe, proliferation resistant, small subcritical fission assembly

  11. Preparation of pediatric patients for treatment with proton beam therapy

    International Nuclear Information System (INIS)

    Mizumoto, Masashi; Oshiro, Yoshiko; Ayuzawa, Kaoru; Miyamoto, Toshio; Okumura, Toshiyuki; Fukushima, Takashi; Fukushima, Hiroko; Ishikawa, Hitoshi; Tsuboi, Koji; Sakurai, Hideyuki

    2015-01-01

    Purpose: Anesthesia is often used in proton beam therapy (PBT) for pediatric patients and this may prolong the treatment time. The aim of the study was to examine preparation of pediatric patients to allow smooth performance of PBT. Material and methods: Preparation was initiated 1–2 days before treatment planning CT and continued for 10 days. The patient first visited the facility to become familiar with the treatment room and staff. As the second step, the patient stayed in the treatment bed for a certain time with their mother, and then stayed on the treatment bed alone. Special fixtures painted with characters, music, and gifts were also prepared. Results: From 2010 to 2014, 111 pediatric patients underwent PBT. These patients were divided into 3 groups: 40 who could follow instructions well (group A, median age: 13.6 years old), 60 who could communicate, but found it difficult to stay alone for a long time (group B, median age: 4.6 years old), and 11 who could not follow instructions (group C, median age: 1.6 years old). Preparation was used for patients in group B. The mean treatment times in groups A, B and C were 13.6, 17.1, and 15.6 min, respectively, on PBT treatment days 2–6, and 11.8, 13.0, and 16.9 min, respectively, for the last 5 days of PBT treatment. The time reduction was significant in group B (p = 0.003). Conclusion: Preparation is useful for pediatric patients who can communicate. This approach allows PBT to be conducted more smoothly over a shorter treatment time

  12. SU-E-T-323: The FLUKA Monte Carlo Code in Ion Beam Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, I [Heidelberg University Hospital (Germany); Ludwig-Maximilian University Munich (Germany)

    2014-06-01

    Purpose: Monte Carlo (MC) codes are increasingly used in the ion beam therapy community due to their detailed description of radiation transport and interaction with matter. The suitability of a MC code demands accurate and reliable physical models for the transport and the interaction of all components of the mixed radiation field. This contribution will address an overview of the recent developments in the FLUKA code oriented to its application in ion beam therapy. Methods: FLUKA is a general purpose MC code which allows the calculations of particle transport and interactions with matter, covering an extended range of applications. The user can manage the code through a graphic interface (FLAIR) developed using the Python programming language. Results: This contribution will present recent refinements in the description of the ionization processes and comparisons between FLUKA results and experimental data of ion beam therapy facilities. Moreover, several validations of the largely improved FLUKA nuclear models for imaging application to treatment monitoring will be shown. The complex calculation of prompt gamma ray emission compares favorably with experimental data and can be considered adequate for the intended applications. New features in the modeling of proton induced nuclear interactions also provide reliable cross section predictions for the production of radionuclides. Of great interest for the community are the developments introduced in FLAIR. The most recent efforts concern the capability of importing computed-tomography images in order to build automatically patient geometries and the implementation of different types of existing positron-emission-tomography scanner devices for imaging applications. Conclusion: The FLUA code has been already chosen as reference MC code in many ion beam therapy centers, and is being continuously improved in order to match the needs of ion beam therapy applications. Parts of this work have been supported by the European

  13. WE-A-207-02: Electron Beam Therapy - Current Status and Future Directions

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Q. [Duke University Medical Center (United States)

    2015-06-15

    In memory of the significant contribution of Dr. Jacques Ovadia to electron beam techniques, this session will review recent, advanced techniques which are reinvigorating the science of electron beam radiation therapy. Recent research efforts in improving both the applicability and quality of the electron beam therapy will be discussed, including modulated electron beam radiotherapy (MERT) and dynamic electron arc radiotherapy (DEAR). Learning Objectives: To learn about recent advances in electron beam therapy, including modulated electron beam therapy and dynamic electron arc therapy (DEAR). Put recent advances in the context of work that Dr. Ovadia pursued during his career in medical physics.

  14. WE-A-207-02: Electron Beam Therapy - Current Status and Future Directions

    International Nuclear Information System (INIS)

    Wu, Q.

    2015-01-01

    In memory of the significant contribution of Dr. Jacques Ovadia to electron beam techniques, this session will review recent, advanced techniques which are reinvigorating the science of electron beam radiation therapy. Recent research efforts in improving both the applicability and quality of the electron beam therapy will be discussed, including modulated electron beam radiotherapy (MERT) and dynamic electron arc radiotherapy (DEAR). Learning Objectives: To learn about recent advances in electron beam therapy, including modulated electron beam therapy and dynamic electron arc therapy (DEAR). Put recent advances in the context of work that Dr. Ovadia pursued during his career in medical physics

  15. Secondary beam monitors for the NuMI facility at FNAL

    International Nuclear Information System (INIS)

    Kopp, S.; Bishai, M.; Dierckxsens, M.; Diwan, M.; Erwin, A.R.; Harris, D.A.; Indurthy, D.; Keisler, R.; Kostin, M.; Lang, M.; MacDonald, J.; Marchionni, A.; Mendoza, S.; Morfin, J.; Naples, D.; Northacker, D.; Pavlovic, Z.; Phelps, L.; Ping, H.; Proga, M.; Vellissaris, C.; Viren, B.; Zwaska, R.

    2006-01-01

    The Neutrinos at the Main Injector (NuMI) facility is a conventional neutrino beam which produces muon neutrinos by focusing a beam of mesons into a long evacuated decay volume. We have built four arrays of ionization chambers to monitor the position and intensity of the hadron and muon beams associated with neutrino production at locations downstream of the decay volume. This article describes the chambers' construction, calibration, and commissioning in the beam

  16. Proton beam therapy how protons are revolutionizing cancer treatment

    CERN Document Server

    Yajnik, Santosh

    2013-01-01

    Proton beam therapy is an emerging technology with promise of revolutionizing the treatment of cancer. While nearly half of all patients diagnosed with cancer in the US receive radiation therapy, the majority is delivered via electron accelerators, where photons are used to irradiate cancerous tissue. Because of the physical properties of photon beams, photons may deposit energy along their entire path length through the body. On the other hand, a proton beam directed at a tumor travels in a straight trajectory towards its target, gives off most of its energy at a defined depth called the Bragg peak, and then stops. While photons often deposit more energy within the healthy tissues of the body than within the cancer itself, protons can deposit most of their cancer-killing energy within the area of the tumor. As a result, in the properly selected patients, proton beam therapy has the ability to improve cure rates by increasing the dose delivered to the tumor and simultaneously reduce side-effects by decreasing...

  17. Clinical results of proton beam therapy for skull base chordoma

    International Nuclear Information System (INIS)

    Igaki, Hiroshi; Tokuuye, Koichi; Okumura, Toshiyuki; Sugahara, Shinji; Kagei, Kenji; Hata, Masaharu; Ohara, Kiyoshi; Hashimoto, Takayuki; Tsuboi, Koji; Takano, Shingo; Matsumura, Akira; Akine, Yasuyuki

    2004-01-01

    Purpose: To evaluate clinical results of proton beam therapy for patients with skull base chordoma. Methods and materials: Thirteen patients with skull base chordoma who were treated with proton beams with or without X-rays at the University of Tsukuba between 1989 and 2000 were retrospectively reviewed. A median total tumor dose of 72.0 Gy (range, 63.0-95.0 Gy) was delivered. The patients were followed for a median period of 69.3 months (range, 14.6-123.4 months). Results: The 5-year local control rate was 46.0%. Cause-specific, overall, and disease-free survival rates at 5 years were 72.2%, 66.7%, and 42.2%, respectively. The local control rate was higher, without statistical significance, for those with preoperative tumors <30 mL. Partial or subtotal tumor removal did not yield better local control rates than for patients who underwent biopsy only as the latest surgery. Conclusion: Proton beam therapy is effective for patients with skull base chordoma, especially for those with small tumors. For a patient with a tumor of <30 mL with no prior treatment, biopsy without tumor removal seems to be appropriate before proton beam therapy

  18. Characterization of a 5-eV neutral atomic oxygen beam facility

    Science.gov (United States)

    Vaughn, J. A.; Linton, R. C.; Carruth, M. R., Jr.; Whitaker, A. F.; Cuthbertson, J. W.; Langer, W. D.; Motley, R. W.

    1991-01-01

    An experimental effort to characterize an existing 5-eV neutral atomic oxygen beam facility being developed at Princeton Plasma Physics Laboratory is described. This characterization effort includes atomic oxygen flux and flux distribution measurements using a catalytic probe, energy determination using a commercially designed quadrupole mass spectrometer (QMS), and the exposure of oxygen-sensitive materials in this beam facility. Also, comparisons were drawn between the reaction efficiencies of materials exposed in plasma ashers, and the reaction efficiencies previously estimated from space flight experiments. The results of this study show that the beam facility is capable of producing a directional beam of neutral atomic oxygen atoms with the needed flux and energy to simulate low Earth orbit (LEO) conditions for real time accelerated testing. The flux distribution in this facility is uniform to +/- 6 percent of the peak flux over a beam diameter of 6 cm.

  19. Reliability analysis of minimum energy on target for laser facilities with more beam lines

    International Nuclear Information System (INIS)

    Chen Guangyu

    2008-01-01

    Shot reliability performance measures of laser facilities with more beam lines pertain to three categories: minimum-energy-on-target, power balance, and shot diagnostics. Accounting for symmetry of NIF beam line design and similarity of subset reliability in a same partition, a fault tree of meeting minimum-energy-on-target for the large laser facility shot of type K and a simplified method are presented, which are used to analyze hypothetic reliability of partition subsets in order to get trends of influences increasing number of beam lines and diverse shot types of large laser facilities on their shot reliability. Finally, it finds that improving component reliability is more crucial for laser facilities with more beam lines in comparison with those with beam lines and functional diversity from design flexibility is greatly helpful for improving shot reliability. (authors)

  20. Examination of Beryllium Under Intense High Energy Proton Beam at CERN's HiRadMat Facility

    CERN Document Server

    Ammigan, K.; Hurh, P.; Zwaska, R.; Atherton, A.; Caretta, O.; Davenne,T.; Densham, C.; Fitton, M.; Loveridge, P.; O'Dell, J.; Roberts, S.; Kuksenko, V.; Butcher, M.; Calviani, M.; Guinchard, M.; Losito, R.

    2017-01-01

    Beryllium is extensively used in various accelerator beam lines and target facilities as material for beam win- dows, and to a lesser extent, as secondary particle produc- tion targets. With increasing beam intensities of future ac- celerator facilities, it is critical to understand the response of beryllium under extreme conditions to avoid compro- mising particle production efficiency by limiting beam pa- rameters. As a result, the planned experiment at CERN’s HiRadMat facility will take advantage of the test facility’s tunable high intensity proton beam to probe and investigate the damage mechanisms of several grades of beryllium. The test matrix will consist of multiple arrays of thin discs of varying thicknesses as well as cylinders, each exposed to increasing beam intensities. Online instrumentations will acquire real time temperature, strain, and vibration data of the cylinders, while Post-Irradiation-Examination (PIE) of the discs will exploit advanced microstructural characteri- zation and imagin...

  1. Examination of Beryllium Under Intense High Energy Proton Beam at CERN's HiRadMat Facility

    CERN Document Server

    Ammigan, K; Hurh, P; Zwaska, R; Atherton, A; Caretta, O; Davenne, t; Densham, C; Fitton, M; Loveridge, P; O'Dell, J; Roberts, S; Kuksenko, v; Butcher, M; Calviani, M; Guinchard, M; Losito, R

    2015-01-01

    Beryllium is extensively used in various accelerator beam lines and target facilities as material for beam win- dows, and to a lesser extent, as secondary particle produc- tion targets. With increasing beam intensities of future ac- celerator facilities, it is critical to understand the response of beryllium under extreme conditions to avoid compro- mising particle production efficiency by limiting beam pa- rameters. As a result, the planned experiment at CERN’s HiRadMat facility will take advantage of the test facility’s tunable high intensity proton beam to probe and investigate the damage mechanisms of several grades of beryllium. The test matrix will consist of multiple arrays of thin discs of varying thicknesses as well as cylinders, each exposed to increasing beam intensities. Online instrumentations will acquire real time temperature, strain, and vibration data of the cylinders, while Post-Irradiation-Examination (PIE) of the discs will exploit advanced microstructural characteri- zation and imagin...

  2. Nano-scale processes behind ion-beam cancer therapy

    Science.gov (United States)

    Surdutovich, Eugene; Garcia, Gustavo; Mason, Nigel; Solov'yov, Andrey V.

    2016-04-01

    This topical issue collates a series of papers based on new data reported at the third Nano-IBCT Conference of the COST Action MP1002: Nanoscale Insights into Ion Beam Cancer Therapy, held in Boppard, Germany, from October 27th to October 31st, 2014. The Nano-IBCT COST Action was launched in December 2010 and brought together more than 300 experts from different disciplines (physics, chemistry, biology) with specialists in radiation damage of biological matter from hadron-therapy centres, and medical institutions. This meeting followed the first and the second conferences of the Action held in October 2011 in Caen, France and in May 2013 in Sopot, Poland respectively. This conference series provided a focus for the European research community and has highlighted the pioneering research into the fundamental processes underpinning ion beam cancer therapy. Contribution to the Topical Issue "COST Action Nano-IBCT: Nano-scale Processes Behind Ion-Beam Cancer Therapy", edited by Andrey V. Solov'yov, Nigel Mason, Gustavo Garcia and Eugene Surdutovich.

  3. Heavy charged particle radiobiology: using enhanced biological effectiveness and improved beam focusing to advance cancer therapy.

    Science.gov (United States)

    Allen, Christopher; Borak, Thomas B; Tsujii, Hirohiko; Nickoloff, Jac A

    2011-06-03

    Ionizing radiation causes many types of DNA damage, including base damage and single- and double-strand breaks. Photons, including X-rays and γ-rays, are the most widely used type of ionizing radiation in radiobiology experiments, and in radiation cancer therapy. Charged particles, including protons and carbon ions, are seeing increased use as an alternative therapeutic modality. Although the facilities needed to produce high energy charged particle beams are more costly than photon facilities, particle therapy has shown improved cancer survival rates, reflecting more highly focused dose distributions and more severe DNA damage to tumor cells. Despite early successes of charged particle radiotherapy, there is room for further improvement, and much remains to be learned about normal and cancer cell responses to charged particle radiation. 2011 Elsevier B.V. All rights reserved.

  4. Controls and Beam Diagnostics for Therapy-Accelerators

    CERN Document Server

    Eickhoff, H

    2000-01-01

    During the last four years GSI has developed a new procedure for cancer treatment by means of the intensity controlled rasterscan-method. This method includes active variations of beam parameters during the treatment session and the integration of 'on-line' PET monitoring. Starting in 1997 several patients have been successfully treated within this GSI experimental cancer treatment program; within this program about 350 patients shall be treated in the next 5 years. The developments and experiences of this program accompanied by intensive discussions with the medical community led to a proposal for a hospital based light ion accelerator facility for the clinic in Heidelberg. An essential part for patients treatments is the measurement of the beam properties within acceptance and constancy tests and especially for the rasterscan method during the treatment sessions. The presented description of the accelerator controls and beam diagnostic devices mainly covers the requests for the active scanning method, which...

  5. HiRadMat: A high‐energy, pulsed beam, material irradiation facility

    CERN Multimedia

    Charitonidis, Nikolaos

    2016-01-01

    HiRadMat is a facility constructed in 2011, designed to provide high-intensity pulsed beams to an irradiation area where different material samples or accelerator components can be tested. The facility, located at the CERN SPS accelerator complex, uses a 440 GeV proton beam with a pulse length up to 7.2 μs and a maximum intensity up to 1E13 protons / pulse. The facility, a unique place for performing state-of-the art beam-to-material experiments, operates under transnational access and welcomes and financially supports, under certain conditions, experimental teams to perform their experiments.

  6. Experiments and FLUKA simulations of $^{12}C$ and $^{16}O$ beams for therapy monitoring by means of in-beam Positron Emission Tomography

    CERN Document Server

    Sommerer,; Ferrari, A

    2007-01-01

    Since 1997 at the experimental C-12 ion therapy facility at Gesellschaft fuer Schwerionenforschung (GSI), Darmstadt, Germany, more than 350 patients have been treated. The therapy is monitored with a dedicated positron emission tomograph, fully integrated into the treatment site. The measured beta+-activity arises from inelastic nuclear interactions between the beam particles an the nuclei of the patients tissue. Because the monitoring is done during the irradiation the method is called in-beam PET. The underlying principle of this monitoring is a comparison between the measured activity and a simulated one. The simulations are presently done by the PETSIM code which is dedicated to C-12 beams. In future ion therapy centers like the Heidelberger Ionenstrahl Therapiezentrum (HIT), Heidelberg, Germany, besides C-12 also proton, $^3$He and O-16 beams will be used for treatment and the therapy will be monitored by means of in-beam PET. Because PETSIM is not extendable to other ions in an easy way, a code capable ...

  7. Radioactive nuclear beam facilities based on projectile fragmentation

    International Nuclear Information System (INIS)

    Sherrill, B.M.

    1992-01-01

    The production of radioactive beams using direct separation techniques is discussed. The reaction mechanisms which can be used to produce radioactive beams with these techniques can be broadly divided into three groups, projectile fragmentation, nucleon transfer, and Coulomb disassociation. Radioactive nuclei produced in these ways have large forward momenta with relatively sharp angular distributions peaked near zero degrees which are suitable for collection with magnetic devices. Secondary beam intensities of up to a few percent of the primary beam intensity are possible, although depending on the production mechanism the beam emittance may be poor. Further beam purification can be achieved using atomic processes with profiled energy degraders. The features of the production reaction mechanism, separation techniques, and a review of world wide efforts are presented. The advantages and disadvantages of the method are presented, with discussion of techniques to overcome some of the disadvantages. (Author)

  8. Skin protection by sucralfate cream during electron beam therapy

    International Nuclear Information System (INIS)

    Maiche, A.

    1994-01-01

    We performed a double-blind randomized study to compare the efficacy of sucralfate cream to a base cream in 50 breast cancer patients receiving postoperative electron beam therapy to their chest wall. The acute radiation reaction of the skin was statistically significantly prevented by the sucralfate cream. The recovery of the skin was also significantly faster in the sucralfate cream group. Side-effects due to the cream were rare. (orig./MG)

  9. Skin protection by sucralfate cream during electron beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Maiche, A. (Helsinki Univ. Central Hospital (Finland). Dept. of Radiotherapy and Oncology); Isokangas, O.P. (Helsinki Univ. Central Hospital (Finland). Dept. of Radiotherapy and Oncology); Groehn, P. (Deaconess Hospital, Helsinki (Finland))

    1994-01-01

    We performed a double-blind randomized study to compare the efficacy of sucralfate cream to a base cream in 50 breast cancer patients receiving postoperative electron beam therapy to their chest wall. The acute radiation reaction of the skin was statistically significantly prevented by the sucralfate cream. The recovery of the skin was also significantly faster in the sucralfate cream group. Side-effects due to the cream were rare. (orig./MG).

  10. Design of the radioactive ion beam facility at the LNS

    International Nuclear Information System (INIS)

    Migneco, E.; Alba, R.; Calabretta, L.; Ciavola, G.; Cuttone, G.; Di Giacomo, M.; Gammino, S.; Gmaj, P.; Moscatello, M.H.; Raia, G.

    1992-01-01

    At the Laboratorio Nazionale del Sud the existing 15 MV Tandem will be coupled to the Superconducting Cyclotron booster, which will provide light and heavy ion beams in the energy range 100-20 MeV/n. Using these beams, secondary radioactive beams can be produced by projectile fragmentation. A fragment separator will collect the secondary beam produced at energies near that of the projectile and deliver it into the experimental areas. The possibility of using an ECRIS source for the axial injection into the Cyclotron and producing radioactive ions on a thick source placed inside the Tandem preinjector is also discussed. (author) 7 refs.; 2 figs.; 1 tab

  11. Fault detection and protection system for neutral beam generators on the Neutral Beam Engineering Test Facility (NBETF)

    International Nuclear Information System (INIS)

    deVries, G.J.; Chesley, K.L.; Owren, H.M.

    1983-12-01

    Neutral beam sources, their power supplies and instrumentation can be damaged from high voltage sparkdown or from overheating due to excessive currents. The Neutral Beam Engineering Test Facility (NBETF) in Berkeley has protective electronic hardware that senses a condition outside a safe operating range and generates a response to terminate such a fault condition. A description of this system is presented in this paper. 8 references, 2 figures, 2 tables

  12. Beam brilliance investigation of high current ion beams at GSI heavy ion accelerator facility.

    Science.gov (United States)

    Adonin, A A; Hollinger, R

    2014-02-01

    In this work the emittance measurements of high current Ta-beam provided by VARIS (Vacuum Arc Ion Source) ion source are presented. Beam brilliance as a function of beam aperture at various extraction conditions is investigated. Influence of electrostatic ion beam compression in post acceleration gap on the beam quality is discussed. Use of different extraction systems (single aperture, 7 holes, and 13 holes) in order to achieve more peaked beam core is considered. The possible ways to increase the beam brilliance are discussed.

  13. Accelerator Based Neutron Beams for Neutron Capture Therapy

    International Nuclear Information System (INIS)

    Yanch, Jacquelyn C.

    2003-01-01

    The DOE-funded accelerator BNCT program at the Massachusetts Institute of Technology has resulted in the only operating accelerator-based epithermal neutron beam facility capable of generating significant dose rates in the world. With five separate beamlines and two different epithermal neutron beam assemblies installed, we are currently capable of treating patients with rheumatoid arthritis in less than 15 minutes (knee joints) or 4 minutes (finger joints) or irradiating patients with shallow brain tumors to a healthy tissue dose of 12.6 Gy in 3.6 hours. The accelerator, designed by Newton scientific Incorporated, is located in dedicated laboratory space that MIT renovated specifically for this project. The Laboratory for Accelerator Beam Applications consists of an accelerator room, a control room, a shielded radiation vault, and additional laboratory space nearby. In addition to the design, construction and characterization of the tandem electrostatic accelerator, this program also resulted in other significant accomplishments. Assemblies for generating epithermal neutron beams were designed, constructed and experimentally evaluated using mixed-field dosimetry techniques. Strategies for target construction and target cooling were implemented and tested. We demonstrated that the method of submerged jet impingement using water as the coolant is capable of handling power densities of up to 6 x 10(sup 7) W/m(sup 2) with heat transfer coefficients of 10(sup 6)W/m(sup 2)-K. Experiments with the liquid metal gallium demonstrated its superiority compared with water with little effect on the neutronic properties of the epithermal beam. Monoenergetic proton beams generated using the accelerator were used to evaluate proton RBE as a function of LET and demonstrated a maximum RBE at approximately 30-40 keV/um, a finding consistent with results published by other researchers. We also developed an experimental approach to biological intercomparison of epithermal beams and

  14. Beta Beams: an accelerator based facility to explore Neutrino oscillation physics

    CERN Document Server

    Wildner, E; Hansen, C; De Melo Mendonca, T; Stora, T; Payet, J; Chance, A; Zorin, V; Izotov, I; Rasin, S; Sidorov, A; Skalyga, V; De Angelis, G; Prete, G; Cinausero, M; Kravchuk, VL; Gramegna, F; Marchi, T; Collazuol, G; De Rosa, G; Delbar, T; Loiselet, M; Keutgen, T; Mitrofanov, S; Lamy, T; Latrasse, L; Marie-Jeanne, M; Sortais, P; Thuillier, T; Debray, F; Trophime, C; Hass, M; Hirsh, T; Berkovits, D; Stahl, A

    2011-01-01

    The discovery that the neutrino changes flavor as it travels through space has implications for the Standard Model of particle physics (SM)[1]. To know the contribution of neutrinos to the SM, needs precise measurements of the parameters governing the neutrino oscillations. This will require a high intensity beam-based neutrino oscillation facility. The EURONu Design Study will review three currently accepted methods of realizing this facility (the so-called Super-Beams, Beta Beams and Neutrino Factories) and perform a cost assessment that, coupled with the physics performance, will give means to the European research authorities to make a decision on the layout and construction of the future European neutrino oscillation facility. ”Beta Beams” produce collimated pure electron neutrino and antineutrino beams by accelerating beta active ions to high energies and letting them decay in a race-track shaped storage ring. EURONu Beta Beams are based on CERNs infrastructure and the fact that some of the already ...

  15. Electron beam accelerator facilities at IPEN-CNEN/SP

    Energy Technology Data Exchange (ETDEWEB)

    Somessari, Samir L.; Silveira, Carlos G. da; Paes, Helio; Somessari, Elizabeth S.R. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)], E-mail: somessar@ipen.br

    2007-07-01

    Electron beam processing is a manufacturing technique, which applies a focused beam of high-energy electrons produced by an electron accelerator to promote chemical changes within a product. At IPEN-CNEN/SP there are two electron beam accelerators Type Dynamitron{sup R} (manufactured by RDI- Radiation Dynamics Inc.) Job 188 and Job 307 models. The technical specifications for the Job 188 energy 1.5 MeV, beam current 25 mA, scan 1.20 m, beam power 37.5 kW and for the Job 307 energy 1.5 MeV, beam current 65 mA, Scan 1.20 m, beam power 97.5 kW. Some applications of the electron beam accelerator for radiation processing are wire and cable insulation crosslinking, rubber vulcanization, sterilization and disinfection of medical products, food preservation, heat shrinkable products, polymer degradation, aseptic packaging, semiconductors and pollution control. For irradiating these materials at IPEN-CNEN/SP, there are some equipment such as, underbeam capstan with speed control from 10 to 700 m/min; a track; a system to roll up and unroll wires and electric cables, polyethylene blankets and other systems to improve the quality of the products. (author)

  16. The ITER neutral beam test facility: Designs of the general infrastructure, cryosystem and cooling plant

    International Nuclear Information System (INIS)

    Cordier, J.J.; Hemsworth, R.; Chantant, M.; Gravil, B.; Henry, D.; Sabathier, F.; Doceul, L.; Thomas, E.; Houtte, D. van; Zaccaria, P.; Antoni, V.; Bello, S. Dal; Marcuzzi, D.; Antipenkov, A.; Day, C.; Dremel, M.; Mondino, P.L.

    2005-01-01

    The CEA Association is involved, in close collaboration with ENEA, FZK, IPP and UKAEA European Associations, in the first ITER neutral beam (NB) injector and the ITER neutral beam test facility design (EFDA task ref. TW3-THHN-IITF1). A total power of about 50 MW will have to be removed in steady state on the neutral beam test facility (NBTF). The main purpose of this task is to make progress with the detailed design of the first ITER NB injector and to start the conceptual design of the ITER NBTF. The general infrastructure layout of a generic site for the NBTF includes the test facility itself equipped with a dedicated beamline vessel [P.L. Zaccaria, et al., Maintenance schemes for the ITER neutral beam test facility, this conference] and integration studies of associated auxiliaries such as cooling plant, cryoplant and forepumping system

  17. Radioactive beam diagnostics status and development at the Spiral facility

    International Nuclear Information System (INIS)

    Chautard, F.; Baelde, J.L.; Bucaille, F.; Duneau, P.; Galard, C.; Le Blay, J.P.; Loyant, J.M.; Martina, L.; Ulrich, M.; Laune, B.

    2001-01-01

    In 2001 the first radioactive beam will be accelerated in the CIME cyclotron of the SPIRAL project at GANIL. In order to be able to tune such low intensity beams in the cyclotron (down to few particles per second), a silicon and a scintillator detectors are mounted on probes. They measure the beam energy and the beam phase/RF in the cyclotron as a function of the radius. Such fragile diagnostics are meant to be used routinely from the control room by non-specialists in instrumentation and in presence of various beam intensities. Therefore, a program is developed to control and secure the acquisition procedure, the measurements and the isochronism correction. Additional detectors are installed at a fixed position in the ejection line before the experimental areas. Additionally, a diamond detector is foreseen to be installed in the machine to be tested in order to ease the CIME operation. (authors)

  18. Unbunched beam electron-proton instability in the PSR and advanced hadron facilities

    International Nuclear Information System (INIS)

    Wang, Tai-Sen; Pisent, A.; Neuffer, D.V.

    1989-01-01

    We studied the possibility of the occurrence of transverse instability induced by trapped electrons in unbunched beams in the Proton Storage Ring and the proposed Advance Hadron Facility (AHF) at Los Alamos, as well as in the proposed Kaon Factory at TRIUMF. We found that the e-p instability may be possible for unbunched beams in the PSR but is unlikely to occur in the advanced hadron facilities. 8 refs., 4 figs

  19. The GSI plans for an international accelerator facility for beams of ions and antiprotons

    International Nuclear Information System (INIS)

    Suemmerer, K.

    2003-01-01

    GSI proposes to build a next-generation facility for research with relativistic beams of ions and antiprotons. This facility allows a broad range of topics in nuclear and astrophysics, plasma and atomic physics to be addressed. The topic most interesting in the context of this conference is physics with high-intensity beams of exotic nuclei. In addition, a short overview of the opportunities in the other fields of nuclear physics is given

  20. Simulation of Particle Fluxes at the DESY-II Test Beam Facility

    International Nuclear Information System (INIS)

    Schuetz, Anne

    2015-05-01

    In the course of this Master's thesis ''Simulation of Particle Fluxes at the DESY-II Test Beam Facility'' the test beam generation for the DESY test beam line was studied in detail and simulated with the simulation software SLIC. SLIC uses the Geant4 toolkit for realistic Monte Carlo simulations of particles passing through detector material.After discussing the physics processes relevant for the test beam generation and the principles of the beam generation itself, the software used is introduced together with a description of the functionality of the Geant4 Monte Carlo simulation. The simulation of the test beam line follows the sequence of the test beam generation. Therefore, it starts with the simulation of the beam bunch of the synchrotron accelerator DESY-II, and proceeds step by step with the single test beam line components. An additional benefit of this thesis is the provision of particle flux and trajectory maps, which make fluxes directly visible by following the particle tracks through the simulated beam line. These maps allow us to see each of the test beam line components, because flux rates and directions change rapidly at these points. They will also guide the decision for placements of future test beam line components and measurement equipment.In the end, the beam energy and its spread, and the beam rate of the final test beam in the test beam area were studied in the simulation, so that the results can be compared to the measured beam parameters. The test beam simulation of this Master's thesis will serve as a key input for future test beam line improvements.

  1. Design of radiation shielding for the proton therapy facility at the National Cancer Center in Korea

    International Nuclear Information System (INIS)

    Kim, J. W.; Kwon, J. W.; Lee, J.

    2005-01-01

    The design of radiation shielding was evaluated for a proton therapy facility being established at the National Cancer Center in Korea. The proton beam energy from a 230 MeV cyclotron is varied for therapy using a graphite target. This energy variation process produces high radiation and thus thick shielding walls surround the region. The evaluation was first carried out using analytical expressions at selected locations. Further detailed evaluations have been performed using the Monte Carlo method. Dose equivalent values were calculated to be compared with analytical results. The analytical method generally yielded more conservative values. With consideration of adequate occupancy factors annual dose equivalent rates are kept -1 in all areas. Construction of the building is expected to be completed near the end of 2004 and the installation of therapy equipments will begin a few months later. (authors)

  2. Power Burst Reactor Facility as an epithermal neutron source for brain cancer therapy

    International Nuclear Information System (INIS)

    Wheeler, F.J.

    1986-01-01

    The Power Burst Facility (PBF) reactor is considered for modification to provide an intense, clean source of intermediate-energy (epithermal) neutrons desirable for clinical studies of neutron capture therapy (NCT) for malignant tumors. The modifications include partial replacement of the reflector, installation of a neutron-moderating, shifting region, additional shielding, and penetration of the present concrete shield with a collimating (and optionally) filtering region. The studies have indicated that the reactor, after these modifications, will be safely operable at full power (28 MW) within the acceptable limits of the plant protection systems. The neutron beam exiting from the collimator port is predicted to be of sufficient intensity (approx.10 10 neutrons/cm 2 -s) to provide therapeutic doses in very short irradiation times. The beam would be relatively free of undesirable fast neutrons, thermal neutrons and gamma rays. The calculated neutron energy spectrum and associated gamma rays in the beam were provided as input in simulation studies that used a computer model of a patient with a brain tumor to determine predicted dose rates to the tumor and healthy tissue. The results of this conceptual study indicate an intense, clean beam of epithermal neutrons for NCT clinical trials is attainable in the PBF facility with properly engineered design modifications. 9 refs., 11 figs., 3 tabs

  3. New electron beam facility for irradiated plasma facing materials testing in hot cell

    International Nuclear Information System (INIS)

    Sakamoto, N.; Kawamura, H.; Akiba, M.

    1995-01-01

    Since plasma facing components such as the first wall and the divertor for the next step fusion reactors are exposed to high heat loads and high energy neutron flux generated by the plasma, it is urgent to develop of plasma facing components which can resist these. Then, we have established electron beam heat facility (open-quotes OHBISclose quotes, Oarai Hot-cell electron Beam Irradiating System) at a hot cell in JMTR (Japan Materials Testing Reactor) hot laboratory in order to estimate thermal shock resistivity of plasma facing materials and heat removal capabilities of divertor elements under steady state heating. In this facility, irradiated plasma facing materials (beryllium, carbon based materials and so on) and divertor elements can be treated. This facility consists of an electron beam unit with the maximum beam power of 50kW and the vacuum vessel. The acceleration voltage and the maximum beam current are 30kV (constant) and 1.7A, respectively. The loading time of electron beam is more than 0.1ms. The shape of vacuum vessel is cylindrical, and the mainly dimensions are 500mm in inner diameter, 1000mm in height. The ultimate vacuum of this vessel is 1 x 10 -4 Pa. At present, the facility for thermal shock test has been established in a hot cell. And performance estimation on the electron beam is being conducted. Presently, the devices for heat loading tests under steady state will be added to this facility

  4. New electron beam facility for irradiated plasma facing materials testing in hot cell

    International Nuclear Information System (INIS)

    Shimakawa, S.; Akiba, M.; Kawamura, H.

    1996-01-01

    Since plasma facing components such as the first wall and the divertor for the next step fusion reactors are exposed to high heat loads and high energy neutron flux generated by the plasma, it is urgent to develop plasma facing components which can resist these. We have established electron beam heat facility ('OHBIS', Oarai hot-cell electron beam irradiating system) at a hot cell in JMTR (Japan materials testing reactor) hot laboratory in order to estimate thermal shock resistivity of plasma facing materials and heat removal capabilities of divertor elements under steady state heating. In this facility, irradiated plasma facing materials (beryllium, carbon based materials and so on) and divertor elements can be treated. This facility consists of an electron beam unit with the maximum beam power of 50 kW and the vacuum vessel. The acceleration voltage and the maximum beam current are 30 kV (constant) and 1.7 A, respectively. The loading time of the electron beam is more than 0.1 ms. The shape of vacuum vessel is cylindrical, and the main dimensions are 500 mm in inside diameter, 1000 mm in height. The ultimate vacuum of this vessel is 1 x 10 -4 Pa. At present, the facility for the thermal shock test has been established in a hot cell. The performance of the electron beam is being evaluated at this time. In the future, the equipment for conducting static heat loadings will be incorporated into the facility. (orig.)

  5. SPES: A new cyclotron-based facility for research and applications with high-intensity beams

    Science.gov (United States)

    Maggiore, M.; Campo, D.; Antonini, P.; Lombardi, A.; Manzolaro, M.; Andrighetto, A.; Monetti, A.; Scarpa, D.; Esposito, J.; Silvestrin, L.

    2017-06-01

    In 2016, Laboratori Nazionali di Legnaro (Italy) started the commissioning of a new accelerator facility based on a high-power cyclotron able to deliver proton beams up to 70 MeV of energy and 700 μA current. Such a machine is the core of the Selective Production of Exotic Species (SPES) project whose main goal is to provide exotics beam for nuclear and astrophysics research and to deliver high-intensity proton beams for medical applications and neutrons generator.

  6. Beamlines of the biomedical imaging and therapy facility at the Canadian light source-Part 1

    International Nuclear Information System (INIS)

    Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka; Thomlinson, William

    2007-01-01

    The BioMedical Imaging and Therapy (BMIT) Facility will provide synchrotron-specific imaging and therapy capabilities. This paper describes one of the BMIT beamlines: the bend magnet (BM) beamline 05B1-1. It plays a complementary role to the insertion device (ID) beamline 051D-2 and allows either monochromatic or filtered white beam to be used in the experimental hutch. The monochromatic spectral range will span 8-40 keV, and the beam is more than 200 mm wide in the experimental hutch for imaging studies of small and medium-size animals (up to sheep size). The experimental hutch will have a positioning system that will allow imaging (computed tomography and planar imaging) as well as radiation therapy applications with both filtered white and monochromatic X-ray beams and will handle subjects up to 120 kg. Several different focal plane detectors (cameras) will be available with resolutions ranging from 10 to 150 μm

  7. The Monte Carlo simulation of the Ladon photon beam facility

    International Nuclear Information System (INIS)

    Strangio, C.

    1976-01-01

    The backward compton scattering of laser light against high energy electrons has been simulated with a Monte Carlo method. The main features of the produced photon beam are reported as well as a careful description of the numerical calculation

  8. Pitfalls of tungsten multileaf collimator in proton beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Moskvin, Vadim; Cheng, Chee-Wai; Das, Indra J. [Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana 46202 (United States) and Indiana University Health Proton Therapy Center (Formerly Midwest Proton Radiotherapy Institute), Bloomington, Indiana 47408 (United States)

    2011-12-15

    Purpose: Particle beam therapy is associated with significant startup and operational cost. Multileaf collimator (MLC) provides an attractive option to improve the efficiency and reduce the treatment cost. A direct transfer of the MLC technology from external beam radiation therapy is intuitively straightforward to proton therapy. However, activation, neutron production, and the associated secondary cancer risk in proton beam should be an important consideration which is evaluated. Methods: Monte Carlo simulation with FLUKA particle transport code was applied in this study for a number of treatment models. The authors have performed a detailed study of the neutron generation, ambient dose equivalent [H*(10)], and activation of a typical tungsten MLC and compared with those obtained from a brass aperture used in a typical proton therapy system. Brass aperture and tungsten MLC were modeled by absorber blocks in this study, representing worst-case scenario of a fully closed collimator. Results: With a tungsten MLC, the secondary neutron dose to the patient is at least 1.5 times higher than that from a brass aperture. The H*(10) from a tungsten MLC at 10 cm downstream is about 22.3 mSv/Gy delivered to water phantom by noncollimated 200 MeV beam of 20 cm diameter compared to 14 mSv/Gy for the brass aperture. For a 30-fraction treatment course, the activity per unit volume in brass aperture reaches 5.3 x 10{sup 4} Bq cm{sup -3} at the end of the last treatment. The activity in brass decreases by a factor of 380 after 24 h, additional 6.2 times after 40 days of cooling, and is reduced to background level after 1 yr. Initial activity in tungsten after 30 days of treating 30 patients per day is about 3.4 times higher than in brass that decreases only by a factor of 2 after 40 days and accumulates to 1.2 x 10{sup 6} Bq cm{sup -3} after a full year of operation. The daily utilization of the MLC leads to buildup of activity with time. The overall activity continues to increase

  9. Dosimetric consequences of pencil beam width variations in scanned beam particle therapy

    International Nuclear Information System (INIS)

    Chanrion, M A; Ammazzalorso, F; Wittig, A; Engenhart-Cabillic, R; Jelen, U

    2013-01-01

    Scanned ion beam delivery enables the highest degree of target dose conformation attainable in external beam radiotherapy. Nominal pencil beam widths (spot sizes) are recorded during treatment planning system commissioning. Due to changes in the beam-line optics, the actual spot sizes may differ from these commissioning values, leading to differences between planned and delivered dose. The purpose of this study was to analyse the dosimetric consequences of spot size variations in particle therapy treatment plans. For 12 patients with skull base tumours and 12 patients with prostate carcinoma, scanned-beam carbon ion and proton treatment plans were prepared and recomputed simulating spot size changes of (1) ±10% to simulate the typical magnitude of fluctuations, (2) ±25% representing the worst-case scenario and (3) ±50% as a part of a risk analysis in case of fault conditions. The primary effect of the spot size variation was a dose deterioration affecting the target edge: loss of target coverage and broadening of the lateral penumbra (increased spot size) or overdosage and contraction of the lateral penumbra (reduced spot size). For changes ⩽25%, the resulting planning target volume mean 95%-isodose line coverage (CI-95%) deterioration was ranging from negligible to moderate. In some cases changes in the dose to adjoining critical structures were observed. (paper)

  10. Demonstration of the importance of a dedicated neutron beam monitoring system for BNCT facility

    International Nuclear Information System (INIS)

    Chao, Der-Sheng; Liu, Yuan-Hao; Jiang, Shiang-Huei

    2016-01-01

    The neutron beam monitoring system is indispensable to BNCT facility in order to achieve an accurate patient dose delivery. The neutron beam monitoring of a reactor-based BNCT (RB-BNCT) facility can be implemented through the instrumentation and control system of a reactor provided that the reactor power level remains constant during reactor operation. However, since the neutron flux in reactor core is highly correlative to complicated reactor kinetics resulting from such as fuel depletion, poison production, and control blade movement, some extent of variation may occur in the spatial distribution of neutron flux in reactor core. Therefore, a dedicated neutron beam monitoring system is needed to be installed in the vicinity of the beam path close to the beam exit of the RB-BNCT facility, where it can measure the BNCT beam intensity as closely as possible and be free from the influence of the objects present around the beam exit. In this study, in order to demonstrate the importance of a dedicated BNCT neutron beam monitoring system, the signals originating from the two in-core neutron detectors installed at THOR were extracted and compared with the three dedicated neutron beam monitors of the THOR BNCT facility. The correlation of the readings between the in-core neutron detectors and the BNCT neutron beam monitors was established to evaluate the improvable quality of the beam intensity measurement inferred by the in-core neutron detectors. In 29 sampled intervals within 16 days of measurement, the fluctuations in the mean value of the normalized ratios between readings of the three BNCT neutron beam monitors lay within 0.2%. However, the normalized ratios of readings of the two in-core neutron detectors to one of the BNCT neutron beam monitors show great fluctuations of 5.9% and 17.5%, respectively. - Highlights: • Two in-core neutron detectors and three BNCT neutron beam monitors were compared. • BNCT neutron beam monitors improve the stability in neutron

  11. Beam-envelope calculations of space-charge loaded beams in MeV dc ion-implantation facilities

    International Nuclear Information System (INIS)

    Urbanus, W.H.; Bannenberg, J.G.; Doorn, S.; Saris, F.W.; Koudijs, R.; Dubbelman, P.; Koelewijn, W.

    1989-01-01

    MeV dc ion accelerators are being developed that can deliver a beam current up to several hundred micro-amperes. At the low-energy part of the accelerator, the beam transport is space-charge dominated rather than emittance dominated. A system of differential equations has been derived, based on the Kapchinski-Vladimirski equations, which describe the envelope of a space-charge loaded ion beam, taking a longitudinal electrical field in an accelerating tube into account. The equations have been used to design the accelerator of a high-current 1 MV heavy-ion implantation facility. Furthermore, the design of a 2 MV accelerator is presented, which is used for analyzing techniques such as RBS and PIXE. Both facilities are based on single-ended Van de Graaff accelerators. (orig.)

  12. Study on beam geometry and image reconstruction algorithm in fast neutron computerized tomography at NECTAR facility

    Science.gov (United States)

    Guo, J.; Bücherl, T.; Zou, Y.; Guo, Z.

    2011-09-01

    Investigations on the fast neutron beam geometry for the NECTAR facility are presented. The results of MCNP simulations and experimental measurements of the beam distributions at NECTAR are compared. Boltzmann functions are used to describe the beam profile in the detection plane assuming the area source to be set up of large number of single neutron point sources. An iterative algebraic reconstruction algorithm is developed, realized and verified by both simulated and measured projection data. The feasibility for improved reconstruction in fast neutron computerized tomography at the NECTAR facility is demonstrated.

  13. Study on beam geometry and image reconstruction algorithm in fast neutron computerized tomography at NECTAR facility

    International Nuclear Information System (INIS)

    Guo, J.; Buecherl, T.; Zou, Y.; Guo, Z.

    2011-01-01

    Investigations on the fast neutron beam geometry for the NECTAR facility are presented. The results of MCNP simulations and experimental measurements of the beam distributions at NECTAR are compared. Boltzmann functions are used to describe the beam profile in the detection plane assuming the area source to be set up of large number of single neutron point sources. An iterative algebraic reconstruction algorithm is developed, realized and verified by both simulated and measured projection data. The feasibility for improved reconstruction in fast neutron computerized tomography at the NECTAR facility is demonstrated.

  14. Study on beam geometry and image reconstruction algorithm in fast neutron computerized tomography at NECTAR facility

    Energy Technology Data Exchange (ETDEWEB)

    Guo, J. [State Key Laboratory of Nuclear Physics and Technology and School of Physics, Peking University, 5 Yiheyuan Lu, Beijing 100871 (China); Lehrstuhl fuer Radiochemie, Technische Universitaet Muenchen, Garching 80748 (Germany); Buecherl, T. [Lehrstuhl fuer Radiochemie, Technische Universitaet Muenchen, Garching 80748 (Germany); Zou, Y., E-mail: zouyubin@pku.edu.cn [State Key Laboratory of Nuclear Physics and Technology and School of Physics, Peking University, 5 Yiheyuan Lu, Beijing 100871 (China); Guo, Z. [State Key Laboratory of Nuclear Physics and Technology and School of Physics, Peking University, 5 Yiheyuan Lu, Beijing 100871 (China)

    2011-09-21

    Investigations on the fast neutron beam geometry for the NECTAR facility are presented. The results of MCNP simulations and experimental measurements of the beam distributions at NECTAR are compared. Boltzmann functions are used to describe the beam profile in the detection plane assuming the area source to be set up of large number of single neutron point sources. An iterative algebraic reconstruction algorithm is developed, realized and verified by both simulated and measured projection data. The feasibility for improved reconstruction in fast neutron computerized tomography at the NECTAR facility is demonstrated.

  15. Lawrence Berkeley laboratory neutral-beam engineering test facility power-supply system

    International Nuclear Information System (INIS)

    Lutz, I.C.; Arthur, C.A.; deVries, G.J.; Owren, H.M.

    1981-10-01

    The Lawrence Berkeley Laboratory is upgrading the neutral beam source test facility (NBSTF) into a neutral beam engineering test facility (NBETF) with increased capabilities for the development of neutral beam systems. The NBETF will have an accel power supply capable of 170 kV, 70 A, 30 sec pulse length, 10% duty cycle; and the auxiliary power supplies required for the sources. This paper describes the major components, their ratings and capabilities, and the flexibility designed to accomodate the needs of source development

  16. The Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Garrett, J.D. [Oak Ridge National Lab., TN (United States)

    1996-12-31

    The status of the new Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory (ORNL), which is slated to start its scientific program late this year is discussed, as is the new experimental equipment which is being constructed at this facility. Information on the early scientific program also is given.

  17. The Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Garrett, J.D.

    1996-01-01

    The status of the new Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory (ORNL), which is slated to start its scientific program late this year is discussed, as is the new experimental equipment which is being constructed at this facility. Information on the early scientific program also is given

  18. Overview of the KoRIA Facility for Rare Isotope Beams

    International Nuclear Information System (INIS)

    Hong, S.W.; Bak, S.I.; Chai, J.S.; Ahn, J.K.; Blumenfeld, Y.; Cheon, B.-G.; Choi, C.I.; Cheoun, M.-K.; Cho, D.; Cho, Y.S.; Choi, B.H.; Choi, E.M.; And others

    2013-01-01

    The Korea Rare Isotope Accelerator, currently referred to as KoRIA, is briefly presented. The KoRIA facility is aimed to enable cutting-edge sciences in a wide range of fields. It consists of a 70 kW isotope separator on-line (ISOL) facility driven by a 70 MeV, 1 mA proton cyclotron and a 400 kW in-flight fragmentation (IFF) facility. The ISOL facility uses a superconducting (SC) linac for post-acceleration of rare isotopes up to about 18 MeV/u, while the SC linac of IFF facility is capable of accelerating uranium beams up to 200 MeV/u, 8 pμA and proton beams up to 600 MeV, 660 μA. Overall features of the KoRIA facility are presented with a focus on the accelerator design. (author)

  19. A large area diamond-based beam tagging hodoscope for ion therapy monitoring

    Science.gov (United States)

    Gallin-Martel, M.-L.; Abbassi, L.; Bes, A.; Bosson, G.; Collot, J.; Crozes, T.; Curtoni, S.; Dauvergne, D.; De Nolf, W.; Fontana, M.; Gallin-Martel, L.; Hostachy, J.-Y.; Krimmer, J.; Lacoste, A.; Marcatili, S.; Morse, J.; Motte, J.-F.; Muraz, J.-F.; Rarbi, F. E.; Rossetto, O.; Salomé, M.; Testa, É.; Vuiart, R.; Yamouni, M.

    2018-01-01

    The MoniDiam project is part of the French national collaboration CLaRyS (Contrôle en Ligne de l'hAdronthérapie par RaYonnements Secondaires) for on-line monitoring of hadron therapy. It relies on the imaging of nuclear reaction products that is related to the ion range. The goal here is to provide large area beam detectors with a high detection efficiency for carbon or proton beams giving time and position measurement at 100 MHz count rates (beam tagging hodoscope). High radiation hardness and intrinsic electronic properties make diamonds reliable and very fast detectors with a good signal to noise ratio. Commercial Chemical Vapor Deposited (CVD) poly-crystalline, heteroepitaxial and monocrystalline diamonds were studied. Their applicability as a particle detector was investigated using α and β radioactive sources, 95 MeV/u carbon ion beams at GANIL and 8.5 keV X-ray photon bunches from ESRF. This facility offers the unique capability of providing a focused ( 1 μm) beam in bunches of 100 ps duration, with an almost uniform energy deposition in the irradiated detector volume, therefore mimicking the interaction of single ions. A signal rise time resolution ranging from 20 to 90 ps rms and an energy resolution of 7 to 9% were measured using diamonds with aluminum disk shaped surface metallization. This enabled us to conclude that polycrystalline CVD diamond detectors are good candidates for our beam tagging hodoscope development. Recently, double-side stripped metallized diamonds were tested using the XBIC (X Rays Beam Induced Current) set-up of the ID21 beamline at ESRF which permits us to evaluate the capability of diamond to be used as position sensitive detector. The final detector will consist in a mosaic arrangement of double-side stripped diamond sensors read out by a dedicated fast-integrated electronics of several hundreds of channels.

  20. Optics of beam recirculation in the CEBAF [Continuous Electron Beam Accelerator Facility] cw linac

    International Nuclear Information System (INIS)

    Douglas, D.R.

    1986-01-01

    The use of recirculation in linear accelerator designs requires beam transport systems that will not degrade beam quality. We present a design for the transport lines to be used during recirculation in the CEBAF accelerator. These beam lines are designed to avoid beam degradation through synchrotron radiation excitation or betatron motion mismatch, are insensitive to errors commonly encountered during beam transport, and are optimized for electron beams with energies of 0.5 to 6.0 GeV. Optically, they are linearly isochronous second order achromats based on a ''missing magnet'' FODO structure. We give lattice specifications for, and results of analytic estimates and numerical simulations of the performance of, the beam transport system

  1. Beam diagnostic tools for the negative hydrogen ion source test facility ELISE

    International Nuclear Information System (INIS)

    Nocentini, Riccardo; Fantz, Ursel; Franzen, Peter; Froeschle, Markus; Heinemann, Bernd; Riedl, Rudolf; Ruf, Benjamin; Wuenderlich, Dirk

    2013-01-01

    Highlights: ► We present an overview of beam diagnostic tools foreseen for the new testbed ELISE. ► A sophisticated diagnostic calorimeter allows beam profile measurement. ► A tungsten wire mesh in the beam path provides a qualitative picture of the beam. ► Stripping losses and beam divergence are measured by H α Doppler shift spectroscopy. -- Abstract: The test facility ELISE, presently being commissioned at IPP, is a first step in the R and D roadmap for the RF driven ion source and extraction system of the ITER NBI system. The “half-size” ITER-like test facility includes a negative hydrogen ion source that can be operated for 1 h. ELISE is expected to extract an ion beam of 20 A at 60 kV for 10 s every 3 min, therefore delivering a total power of 1.2 MW. The extraction area has a geometry that closely reproduces the ITER design, with the same width and half the height, i.e. 1 m × 1 m. This paper presents an overview of beam diagnostic tools foreseen for ELISE. For the commissioning phase, a simple beam dump with basic diagnostic capabilities has been installed. In the second phase, the beam dump will be substituted by a more sophisticated diagnostic calorimeter to allow beam profile measurement. Additionally, a tungsten wire mesh will be introduced in the beam path to provide a qualitative picture of beam size and position. Stripping losses and beam divergence will be measured by means of H α Doppler shift spectroscopy. An absolute calibration is foreseen in order to measure beam intensity

  2. Dosimetry auditing procedure with alanine dosimeters for light ion beam therapy

    International Nuclear Information System (INIS)

    Ableitinger, Alexander; Vatnitsky, Stanislav; Herrmann, Rochus; Bassler, Niels; Palmans, Hugo; Sharpe, Peter; Ecker, Swantje; Chaudhri, Naved; Jäkel, Oliver; Georg, Dietmar

    2013-01-01

    Background and purpose: In the next few years the number of facilities providing ion beam therapy with scanning beams will increase. An auditing process based on an end-to-end test (including CT imaging, planning and dose delivery) could help new ion therapy centres to validate their entire logistic chain of radiation delivery. An end-to-end procedure was designed and tested in both scanned proton and carbon ion beams, which may also serve as a dosimetric credentialing procedure for clinical trials in the future. The developed procedure is focused only on physical dose delivery and the validation of the biological dose is out of scope of the current work. Materials and methods: The audit procedure was based on a homogeneous phantom that mimics the dimension of a head (20 × 20 × 21 cm 3 ). The phantom can be loaded either with an ionisation chamber or 20 alanine dosimeters plus 2 radiochromic EBT films. Dose verification aimed at measuring a dose of 10 Gy homogeneously delivered to a virtual-target volume of 8 × 8 × 12 cm 3 . In order to interpret the readout of the irradiated alanine dosimeters additional Monte Carlo simulations were performed to calculate the energy dependent detector response of the particle fluence in the alanine detector. A pilot run was performed with protons and carbon ions at the Heidelberg Ion Therapy facility (HIT). Results: The mean difference of the absolute physical dose measured with the alanine dosimeters compared with the expected dose from the treatment planning system was −2.4 ± 0.9% (1σ) for protons and −2.2 ± 1.1% (1σ) for carbon ions. The measurements performed with the ionisation chamber indicate this slight underdosage with a dose difference of −1.7% for protons and −1.0% for carbon ions. The profiles measured by radiochromic films showed an acceptable homogeneity of about 3%. Conclusions: Alanine dosimeters are suitable detectors for dosimetry audits in ion beam therapy and the presented end-to-end test is

  3. Dosimetry auditing procedure with alanine dosimeters for light ion beam therapy.

    Science.gov (United States)

    Ableitinger, Alexander; Vatnitsky, Stanislav; Herrmann, Rochus; Bassler, Niels; Palmans, Hugo; Sharpe, Peter; Ecker, Swantje; Chaudhri, Naved; Jäkel, Oliver; Georg, Dietmar

    2013-07-01

    In the next few years the number of facilities providing ion beam therapy with scanning beams will increase. An auditing process based on an end-to-end test (including CT imaging, planning and dose delivery) could help new ion therapy centres to validate their entire logistic chain of radiation delivery. An end-to-end procedure was designed and tested in both scanned proton and carbon ion beams, which may also serve as a dosimetric credentialing procedure for clinical trials in the future. The developed procedure is focused only on physical dose delivery and the validation of the biological dose is out of scope of the current work. The audit procedure was based on a homogeneous phantom that mimics the dimension of a head (20 × 20 × 21 cm(3)). The phantom can be loaded either with an ionisation chamber or 20 alanine dosimeters plus 2 radiochromic EBT films. Dose verification aimed at measuring a dose of 10Gy homogeneously delivered to a virtual-target volume of 8 × 8 × 12 cm(3). In order to interpret the readout of the irradiated alanine dosimeters additional Monte Carlo simulations were performed to calculate the energy dependent detector response of the particle fluence in the alanine detector. A pilot run was performed with protons and carbon ions at the Heidelberg Ion Therapy facility (HIT). The mean difference of the absolute physical dose measured with the alanine dosimeters compared with the expected dose from the treatment planning system was -2.4 ± 0.9% (1σ) for protons and -2.2 ± 1.1% (1σ) for carbon ions. The measurements performed with the ionisation chamber indicate this slight underdosage with a dose difference of -1.7% for protons and -1.0% for carbon ions. The profiles measured by radiochromic films showed an acceptable homogeneity of about 3%. Alanine dosimeters are suitable detectors for dosimetry audits in ion beam therapy and the presented end-to-end test is feasible. If further studies show similar results, this dosimetric audit could be

  4. Experimental program with beam in TESLA test facility

    International Nuclear Information System (INIS)

    Mosnier, A.; Aune, B.

    1994-09-01

    In order to establish a technical basis for a high energy e + e - collider using the superconducting RF technology, the test of a string of 32 cavities with beam at an accelerating gradient of 15 MV/m is planned in an installation at DESY. Several experiments with beam in the TTF linac will be performed. The dissipated HOM power at helium temperature is a key issue for TESLA, its estimation requires careful calorimetric measurements and the full charge injector. Bunch wake potentials can be estimated with bunch charges of at least 1 to 2 nC. Multibunch measurements require a beam of a few hundreds of these bunches. The beam will be injected either on axis or off axis. RF steering due to couplers will be estimated by measuring the beam displacement for different RF phase settings. The expected resolution is well below the TESLA specification. The acceleration of dark currents will be observed for different settings of the focusing elements. 7 figs., 1 tab., 3 refs

  5. Test facility of proton beam utilization of the PEFP at the SNU-AMS tandem accelerator

    International Nuclear Information System (INIS)

    Kim, K. R.; Park, B. S.; Lee, H. R.

    2004-01-01

    The PEFP (Proton Engineering Frontier Project) will supply users with a 20-MeV proton beam by the middle of 2007. A survey on users' demand was performed to draw the concept for the 20-MeV user facilities and to investigate users' requirements. In the mean time, a 6-MeV test facility has been developed to give users opportunities to experiment with proton beams. That facility will be attached to the 3-MV tandem accelerator at Seoul National University.

  6. Commissioning experience and beam physics measurements at the SwissFEL Injector Test Facility

    Directory of Open Access Journals (Sweden)

    T. Schietinger

    2016-10-01

    Full Text Available The SwissFEL Injector Test Facility operated at the Paul Scherrer Institute between 2010 and 2014, serving as a pilot plant and test bed for the development and realization of SwissFEL, the x-ray Free-Electron Laser facility under construction at the same institute. The test facility consisted of a laser-driven rf electron gun followed by an S-band booster linac, a magnetic bunch compression chicane and a diagnostic section including a transverse deflecting rf cavity. It delivered electron bunches of up to 200 pC charge and up to 250 MeV beam energy at a repetition rate of 10 Hz. The measurements performed at the test facility not only demonstrated the beam parameters required to drive the first stage of an FEL facility, but also led to significant advances in instrumentation technologies, beam characterization methods and the generation, transport and compression of ultralow-emittance beams. We give a comprehensive overview of the commissioning experience of the principal subsystems and the beam physics measurements performed during the operation of the test facility, including the results of the test of an in-vacuum undulator prototype generating radiation in the vacuum ultraviolet and optical range.

  7. Beam studies and experimental facility for the AWAKE experiment at CERN

    International Nuclear Information System (INIS)

    Bracco, Chiara; Gschwendtner, Edda; Petrenko, Alexey; Timko, Helga; Argyropoulos, Theodoros; Bartosik, Hannes; Bohl, Thomas; Esteban Müller, Juan; Goddard, Brennan; Meddahi, Malika; Pardons, Ans; Shaposhnikova, Elena; Velotti, Francesco M.; Vincke, Helmut

    2014-01-01

    A Proton Driven Plasma Wakefield Acceleration Experiment has been proposed as an approach to eventually accelerate an electron beam to the TeV energy range in a single plasma section. To verify this novel technique, a proof of principle R and D experiment, AWAKE, is planned at CERN using 400 GeV proton bunches from the SPS. An electron beam will be injected into the plasma cell to probe the accelerating wakefield. The AWAKE experiment will be installed in the CNGS facility profiting from existing infrastructure where only minor modifications need to be foreseen. The design of the experimental area and the proton and electron beam lines are shown. The achievable SPS proton bunch properties and their reproducibility have been measured and are presented. - Highlights: • A proton driven plasma wakefield experiment using the first time protons as drive beam is proposed. • The integration of AWAKE experiment, the proton, laser and electron beam line in an existing CERN facility is demonstrated. • The necessary modifications in the experimental facility are presented. • Proton beam optics and a new electron beam line are adapted to match with the required beam parameters. • Short high-intensity bunches were studied in the SPS to guide the design parameters of the AWAKE project

  8. ISAC and ARIEL the TRIUMF radioactive beam facilities and the scientific program

    CERN Document Server

    Krücken, Reiner; Merminga, Lia

    2014-01-01

    The TRIUMF Isotope Separator and Accelerator (ISAC) facility uses the isotope separation on-line (ISOL) technique to produce rare-isotope beams (RIB). The ISOL system consists of a primary production beam, a target/ion source, a mass separator, and beam transport system. The rare isotopes produced during the interaction of the proton beam with the target nucleus are stopped in the bulk of the target material. They diffuse inside the target material matrix to the surface of the grain and then effuse to the ion source where they are ionized to form an ion beam that can be separated by mass and then guided to the experimental facilities. Previously published in the journal Hyperfine Interactions.

  9. Status of the Medaustron Ion Beam Therapy centre

    CERN Document Server

    Dorda, U; Osmic, F; Benedikt, M

    2012-01-01

    MedAustron is a synchrotron based light-ion beam therapy centre for cancer treatment as well as for clinical and non-clinical research currently in its construction phase. The accelerator design is based on the CERN-PIMMS study and its technical implementation by CNAO. This paper presents a status overview over the whole project detailing the achieved progress of the building construction & technical infrastructure installation in Wiener Neustadt, Austria, as well as of the accelerator development, performed at CERN and partially at PSI. The design and procurement status and future planning of the various accelerator components is elaborated.

  10. Alanine EPR dosimeter response in proton therapy beams

    International Nuclear Information System (INIS)

    Gall, K.; Serago, C.; Desrosiers, M.; Bensen, D.

    1997-01-01

    We report a series of measurements directed to assess the suitability of alanine as a mailable dosimeter for dosimetry quality assurance of proton radiation therapy beams. These measurements include dose-response of alanine at 140 MeV, and comparison of response vs energy with a parallel plate ionization chamber. All irradiations were made at the Harvard Cyclotron Laboratory, and the dosimeters were read at NIST. The results encourage us that alanine could be expected to serve as a mailable dosimeter with systematic error due to differential energy response no greater than 3% when doses of 25 Gy are used. (Author)

  11. Two years of operating experience with the Seattle clinical neutron therapy facility

    International Nuclear Information System (INIS)

    Risler, R.; Brossard, S.; Eenmaa, J.; Kalet, I.; Wootton, P.

    1987-01-01

    After five years of planning, equipment acquisition, facility construction and beam testing the Seattle Clinical Neutron Therapy facility became operational in October 1984. In the past two years nearly 300 people have been treated in clinical trials. During this time 82 % of the planned treatment sessions were performed on schedule, 3 % had to be rescheduled for patient related reasons and 15 % because of equipment problems. The facility is at present running on a 5 days/week schedule: Three ten-hour treatment days, one maintenance day and one research day (radiobiology, therapy related physics). Short runs for short lived isotopes are done between patient treatments. The isocentric gantry, capable of 360 rotation is equipped with a variable collimator with 40 independent leaves. This collimation system allows the use of complex field shapes without the necessity of handling radioactive components like collimator inserts or blocks. It has turned out to be a very essential part for the efficient operation of the facility. Major causes for equipment downtime were associated with the control system, the beryllium target system, RF and magnet systems and the treatment gantry. (author)

  12. Present status of high quality beam facility at Waseda University

    International Nuclear Information System (INIS)

    Washio, M.; Kawai, H.; Hama, Y.; Kudo, N.; Kobayashi, M.; Kuribayasi, T.; Kawaguchi, M.; Kuroda, R.; Maeda, K.; Nagasawa, F.; Ueyama, D.; Hizume, K.; Wang, X.J.; Hayano, H.; Urakawa, J.; Kashiwagi, S.

    2004-01-01

    A research project named High-Tech Research Center Project has been conducted at Waseda University. In this project, an RF gun system has been used for production of low emittance and short bunched electron beam. The experiments for the electron beam quality measurement have been carried out by slit scan techniques, etc. Short pulsed x-ray with the energy range of so-called water window has been generation by the inverse compton scattering. Further, the pulse radiolysis system has been constructed, and the stroboscopic pulse radiolysis has been applied for the detection of hydrated electron in picosecond time region. (author)

  13. Two frequency beam-loading compensation in the drive-beam accelerator of the CLIC Test Facility

    CERN Document Server

    Braun, Hans Heinrich

    1999-01-01

    The CLIC Test Facility (CTF) is a prototype two-beam accelerator, in which a high-current "drive beam" is used to generate the RF power for the main-beam accelerator. The drive-beam accelerator consists of two S-band structures which accelerate a bunch train with a total charge of 500 nC. The substantial beam loading is compensated by operating the two accelerating structures at 7.81 MHz above and below the bunch repetition frequency, respectively. This introduces a change of RF phase from bunch to bunch, which leads, together with off-crest injection into the accelerator, to an approximate compensation of the beam loading. Due to the sinusoidal time-dependency of the RF field, an energy spread of about 7% remains in the bunch train. A set of idler cavities has been installed to reduce this residual energy spread further. In this paper, the considerations that motivated the choice of the parameters of the beam-loading compensation system, together with the experimental results, are presented.

  14. Fast pencil beam dose calculation for proton therapy using a double-Gaussian beam model

    Directory of Open Access Journals (Sweden)

    Joakim eda Silva

    2015-12-01

    Full Text Available The highly conformal dose distributions produced by scanned proton pencil beams are more sensitive to motion and anatomical changes than those produced by conventional radiotherapy. The ability to calculate the dose in real time as it is being delivered would enable, for example, online dose monitoring, and is therefore highly desirable. We have previously described an implementation of a pencil beam algorithm running on graphics processing units (GPUs intended specifically for online dose calculation. Here we present an extension to the dose calculation engine employing a double-Gaussian beam model to better account for the low-dose halo. To the best of our knowledge, it is the first such pencil beam algorithm for proton therapy running on a GPU. We employ two different parametrizations for the halo dose, one describing the distribution of secondary particles from nuclear interactions found in the literature and one relying on directly fitting the model to Monte Carlo simulations of pencil beams in water. Despite the large width of the halo contribution, we show how in either case the second Gaussian can be included whilst prolonging the calculation of the investigated plans by no more than 16%, or the calculation of the most time-consuming energy layers by about 25%. Further, the calculation time is relatively unaffected by the parametrization used, which suggests that these results should hold also for different systems. Finally, since the implementation is based on an algorithm employed by a commercial treatment planning system, it is expected that with adequate tuning, it should be able to reproduce the halo dose from a general beam line with sufficient accuracy.

  15. Expanding options in radiation oncology: neutron beam therapy

    International Nuclear Information System (INIS)

    Cohen, L.

    1982-01-01

    Twelve years experience with neutron beam therapy in Britain, the USA, Europe and Japan shows that local control is achievable in late-stage epidermoid cancer somewhat more frequently than with conventional radiotherapy. Tumours reputed to be radioresistant (salivary gland, bladder, rectosigmoid, melanoma, bone and soft-tissue sarcomas) have proved to be particularly responsive to neutrons. Pilot studies in brain and pancreatic tumours suggest promising new approaches to management of cancer in these sites. The availability of neutron therapy in the clinical environment opens new prospects for irradiation of 'radioresistant' tumours, permits more conservative cancer surgery, expands the use of elective chemotherapy and provides a wider range of options for cancer patients. (author)

  16. Improving Outcomes for Esophageal Cancer using Proton Beam Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Chuong, Michael D. [Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Maryland (United States); Hallemeier, Christopher L. [Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota (United States); Jabbour, Salma K. [Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey (United States); Yu, Jen; Badiyan, Shahed [Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Maryland (United States); Merrell, Kenneth W. [Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota (United States); Mishra, Mark V. [Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Maryland (United States); Li, Heng [Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas (United States); Verma, Vivek [Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, Nebraska (United States); Lin, Steven H., E-mail: shlin@mdanderson.org [Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas (United States)

    2016-05-01

    Radiation therapy (RT) plays an essential role in the management of esophageal cancer. Because the esophagus is a centrally located thoracic structure there is a need to balance the delivery of appropriately high dose to the target while minimizing dose to nearby critical structures. Radiation dose received by these critical structures, especially the heart and lungs, may lead to clinically significant toxicities, including pneumonitis, pericarditis, and myocardial infarction. Although technological advancements in photon RT delivery like intensity modulated RT have decreased the risk of such toxicities, a growing body of evidence indicates that further risk reductions are achieved with proton beam therapy (PBT). Herein we review the published dosimetric and clinical PBT literature for esophageal cancer, including motion management considerations, the potential for reirradiation, radiation dose escalation, and ongoing esophageal PBT clinical trials. We also consider the potential cost-effectiveness of PBT relative to photon RT.

  17. OPTIMIZATION OF THE EPITHERMAL NEUTRON BEAM FOR BORON NEUTRON CAPTURE THERAPY AT THE BROOKHAVEN MEDICAL RESEARCH REACTOR.

    Energy Technology Data Exchange (ETDEWEB)

    HU,J.P.; RORER,D.C.; RECINIELLO,R.N.; HOLDEN,N.E.

    2002-08-18

    Clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumor had been carried out for half a decade, using an epithermal neutron beam at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new protocols. Details of the conceptual design to produce a higher intensity, more forward-directed neutron beam with less contamination from gamma rays, fast and thermal neutrons are presented here for their potential applicability to other reactor facilities. Monte Carlo calculations were used to predict the flux and absorbed dose produced by the proposed design. The results were benchmarked by the dose rate and flux measurements taken at the facility then in use.

  18. Optimization study for an epithermal neutron beam for boron neutron capture therapy at the University of Virginia Research Reactor

    International Nuclear Information System (INIS)

    Burns, T.D. Jr.

    1995-05-01

    The non-surgical brain cancer treatment modality, Boron Neutron Capture Therapy (BNCT), requires the use of an epithermal neutron beam. This purpose of this thesis was to design an epithermal neutron beam at the University of Virginia Research Reactor (UVAR) suitable for BNCT applications. A suitable epithermal neutron beam for BNCT must have minimal fast neutron and gamma radiation contamination, and yet retain an appreciable intensity. The low power of the UVAR core makes reaching a balance between beam quality and intensity a very challenging design endeavor. The MCNP monte carlo neutron transport code was used to develop an equivalent core radiation source, and to perform the subsequent neutron transport calculations necessary for beam model analysis and development. The code accuracy was validated by benchmarking output against experimental criticality measurements. An epithermal beam was designed for the UVAR, with performance characteristics comparable to beams at facilities with cores of higher power. The epithermal neutron intensity of this beam is 2.2 x 10 8 n/cm 2 · s. The fast neutron and gamma radiation KERMA factors are 10 x 10 -11 cGy·cm 2 /n epi and 20 x 10 -11 cGy·cm 2 /n epi , respectively, and the current-to-flux ratio is 0.85. This thesis has shown that the UVAR has the capability to provide BNCT treatments, however the performance characteristics of the final beam of this study were limited by the low core power

  19. Cutaneous complication after electron beam therapy in breast cancer

    Directory of Open Access Journals (Sweden)

    M Jalilian

    2005-11-01

    Full Text Available Background: Breast cancer is the most common cancer in women and the second cause of death among them. There are several treatment methods for breast cancer, one of which is radiation therapy. There are two important methods of radiation therapy: tangential field and single oppositional field. Main goal of this study is evaluation of factors that have a role in producing acute side effects such as skin burning in breast cancer patients treated by electron beam,in order to decrease these side effects. Methods: From 1/2003 through 7/2004, 200 consecutive patients were evaluated during 18 months in seid-al-shohad hospital, whose mean age was 49 years old. In this study a questionnaire was used including some questions about personal profile such as patient's name, address, registration number, age and some other factors. All patients who were candidated to enter in this investigation filled out the questionnaire at the end of radiation therapy. The patients were examined and their skin burning grades were evaluated by RTOG scale. Data were analyzed by chi-square test using SPSS 11 software. Results: None of patients showed grades O or 4 of burning. 31.5 % of Patients showed grade 1, 64.5 % showed grade 2, 4 % showed grade 3 of burning. There was statistically significant correlation between posterior axillary field and skin burning and there wasnot any meaning between the other factors. Conclusion: It is necessary to pay more attention to posterior axillary field planning including field size, location, photon energy, depth and dose of treatment. Keywords: breast cancer, electron beam radiation therapy, skin burning

  20. Optics calculations and beam line design for the JANNuS facility in Orsay

    International Nuclear Information System (INIS)

    Chauvin, N.; Henry, S.; Flocard, H.; Fortuna, F.; Kaitasov, O.; Pariset, P.; Pellegrino, S.; Ruault, M.O.; Serruys, Y.; Trocelier, P.

    2007-01-01

    JANNuS (Joint Accelerators for Nano-Science and Nuclear Simulation) will be a unique user facility in Europe dedicated to material modification by ion beam implantation and irradiation. The main originality of the project is that it will be possible to perform implantation and irradiation with simultaneous multiple ions beams and in situ characterization by transmission electron microscopy (TEM) observation or ion beam analysis. This facility will be composed of two experimental platforms located in two sites: the CEA-SRMP in Saclay and the CNRS-CSNSM in Orsay. This paper will focus on the design of two new transport beam lines for the Orsay site. One of the most challenging parts of the JANNuS project (Orsay site) is to design two new beam lines in order to inject, into a 200 kV TEM, two different ion beams (low and medium energy) coming from two existing pieces of equipment: a 2 MV Tandem accelerator and a 190 kV ion implanter. For these new beam lines, first order beam calculations have been done using transfer matrix formalism. A genetic algorithm has been written and adapted to perform the optimization of the beam line parameters. Then, using the SIMION code, field maps of the electrostatic elements (quadrupoles, spherical sectors) have been calculated and ion trajectories have been simulated. We studied specifically the optical aberrations induced by the electrostatic spherical deflectors. Finally, the results of the first order calculations and the field map simulations show a good agreement

  1. Construction of the Neutron Beam Facility at Australia's OPAL Research Reactor

    International Nuclear Information System (INIS)

    Kennedy, J.S.

    2005-01-01

    Full text: Australia's new research reactor, OPAL, has been designed for high quality neutron beam science and radioisotope production. It has a capacity for eighteen neutron beam instruments to be located at the reactor face and in a neutron guide hall. The new neutron beam facility features a 20 litre liquid deuterium cold neutron source and supermirror neutron reflecting guides for intense cold and thermal neutron beams. Nine neutron beam instruments are under development, of which seven are scheduled for completion in early 2007. The project is approaching the hot-commissioning stage, where criticality will be demonstrated. Installation of the neutron beam transport system and neutron beam instruments in the neutron guide hall and at the reactor face is underway, and the path to completion of this project is relatively clear. The lecture will outline Australia's aspirations for neutron science at the OPAL reactor, and describe the neutron beam facility under construction. The status of this project and a forecast of the program to completion, including commissioning and commencement of routine operation in 2007 will also be discussed. This project is the culmination of almost a decade of effort. We now eagerly anticipate catapulting Australia's neutron beam science capability to meet the best in the world today. (author)

  2. ISABELLE: a 200 + 200 GeV colliding beam facility

    International Nuclear Information System (INIS)

    Courant, E.D.

    1977-01-01

    Plans are under way for the construction of a pair of intersecting storage rings providing for colliding beams of protons of energy at least 200 GeV. The rings (circumference 2.62 km) will contain superconducting magnets constructed with braided Nb--Ti filamentary wire, with a peak field of 4.0 T corresponding to an energy of 200 GeV. A current of 10 A of protons will be injected at 29 GeV from the existing AGS accelerator at Brookhaven, using the energy stacking technique similar to that employed at the CERN ISR; subsequently the stored beam will be accelerated gradually in the storage rings. Six intersection areas will be provided for experiments. They are designed to provide flexibility in beam characteristics for different experiments. The maximum luminosity at full energy is expected to be 1.0 x 10 33 cm -2 s -1 , at 29 GeV it will be approximately 10 32 cm -2 s -1 . Recent work with prototype magnets indicates that fields of 5.0 T can be produced. This has led to an alternative design of somewhat larger rings (circumference 3.77 km) that should be capable of providing colliding beams at 400 + 400 GeV

  3. Improvements for extending the time between maintenance periods for the Heidelberg ion beam therapy center (HIT) ion sources

    Energy Technology Data Exchange (ETDEWEB)

    Winkelmann, Tim, E-mail: tim.winkelmann@med.uni-heidelberg.de; Cee, Rainer; Haberer, Thomas; Naas, Bernd; Peters, Andreas; Schreiner, Jochen [Heidelberger Ionenstrahl-Therapie Centrum (HIT), D -69120 Heidelberg (Germany)

    2014-02-15

    The clinical operation at the Heidelberg Ion Beam Therapy Center (HIT) started in November 2009; since then more than 1600 patients have been treated. In a 24/7 operation scheme two 14.5 GHz electron cyclotron resonance ion sources are routinely used to produce protons and carbon ions. The modification of the low energy beam transport line and the integration of a third ion source into the therapy facility will be shown. In the last year we implemented a new extraction system at all three sources to enhance the lifetime of extraction parts and reduce preventive and corrective maintenance. The new four-electrode-design provides electron suppression as well as lower beam emittance. Unwanted beam sputtering effects which typically lead to contamination of the insulator ceramics and subsequent high-voltage break-downs are minimized by the beam guidance of the new extraction system. By this measure the service interval can be increased significantly. As a side effect, the beam emittance can be reduced allowing a less challenging working point for the ion sources without reducing the effective beam performance. This paper gives also an outlook to further enhancements at the HIT ion source testbench.

  4. Commissioning experience and beam physics measurements at the SwissFEL Injector test Facility

    CERN Document Server

    Schietinger, T.; Aiba, M.; Arsov, V.; Bettoni, S.; Beutner, B.; Calvi, M.; Craievich, P.; Dehler, M.; Frei, F.; Ganter, R.; Hauri, C. P.; Ischebeck, R.; Ivanisenko, Y.; Janousch, M.; Kaiser, M.; Keil, B.; Löhl, F.; Orlandi, G. L.; Ozkan Loch, C.; Peier, P.; Prat, E.; Raguin, J.-Y.; Reiche, S.; Schilcher, T.; Wiegand, P.; Zimoch, E.; Anicic, D.; Armstrong, D.; Baldinger, M.; Baldinger, R.; Bertrand, A.; Bitterli, K.; Bopp, M.; Brands, H.; Braun, H. H.; Brönnimann, M.; Brunnenkant, I.; Chevtsov, P.; Chrin, J.; Citterio, A.; Csatari Divall, M.; Dach, M.; Dax, A.; Ditter, R.; Divall, E.; Falone, A.; Fitze, H.; Geiselhart, C.; Guetg, M. W.; Hämmerli, F.; Hauff, A.; Heiniger, M.; Higgs, C.; Hugentobler, W.; Hunziker, S.; Janser, G.; Kalantari, B.; Kalt, R.; Kim, Y.; Koprek, W.; Korhonen, T.; Krempaska, R.; Laznovsky, M.; Lehner, S.; Le Pimpec, F.; Lippuner, T.; Lutz, H.; Mair, S.; Marcellini, F.; Marinkovic, G.; Menzel, R.; Milas, N.; Pal, T.; Pollet, P.; Portmann, W.; Rezaeizadeh, A.; Ritt, S.; Rohrer, M.; Schär, M.; Schebacher, L.; Scherrer, St.; Schlott, V.; Schmidt, T.; Schulz, L.; Smit, B.; Stadler, M.; Steffen, Bernd; Stingelin, L.; Sturzenegger, W.; Treyer, D. M.; Trisorio, A.; Tron, W.; Vicario, C.; Zennaro, R.; Zimoch, D.

    2016-10-26

    The SwissFEL Injector Test Facility operated at the Paul Scherrer Institute between 2010 and 2014, serving as a pilot plant and test bed for the development and realization of SwissFEL, the x-ray Free Electron Laser facility under construction at the same institute. The test facility consisted of a laser-driven rf electron gun followed by an S-band booster linac, a magnetic bunch compression chicane and a diagnostic section including atransverse deflecting rf cavity. It delivered electron bunchesof up to200 pC chargeand up to 250 MeV beam energy at a repetition rate of 10 Hz. The measurements performed at the test facility not only demonstrated the beam parameters required to drive the first stage of a FEL facility, but also led to significant advances in instrumentation technologies, beam characterization methods and the generation, transport and compression of ultralow-emittance beams. We give a comprehensive overview of the commissioning experience of the principal subsystems and the beam physics measureme...

  5. Feasibility of the utilization of BNCT in the fast neutron therapy beam at Fermilab

    International Nuclear Information System (INIS)

    Langen, Katja; Lennox, Arlene J.; Kroc, Thomas K.; DeLuca, Paul M. Jr.

    2000-01-01

    The Neutron Therapy Facility at Fermilab has treated cancer patients since 1976. Since then more than 2,300 patients have been treated and a wealth of clinical information accumulated. The therapeutic neutron beam at Fermilab is produced by bombarding a beryllium target with 66 MeV protons. The resulting continuous neutron spectrum ranges from thermal to 66 MeV in neutron energy. It is clear that this spectrum is not well suited for the treatment of tumors with boron neutron capture therapy (BNCT) only However, since this spectrum contains thermal and epithermal components the authors are investigating whether BNCT can be used in this beam to boost the tumor dose. There are clinical scenarios in which a selective tumor dose boost of 10 - 15% could be clinically significant. For these cases the principal treatment would still be fast neutron therapy but a tumor boost could be used either to deliver a higher dose to the tumor tissue or to reduce the dose to the normal healthy tissue while maintaining the absorbed dose level in the tumor tissue

  6. Report on proton therapy according to good clinical practice at Hyogo Ion Beam Medical Center

    International Nuclear Information System (INIS)

    Murakami, Masao; Kagawa, Kazufumi; Hishikawa, Yoshio; Abe, Mitsuyuki

    2002-01-01

    The Hyogo Ion Beam Medical Center (HIBMC) is a hospital-based charged particle treatment facility. Having two treatment ion beams (proton and carbon) and five treatment rooms, it is a pioneer among particle institutes worldwide. In May 2001, proton therapy was started as a clinical study for patients with localized cancer originating in the head and neck, lung, liver, and prostate. The aim of this study was to investigate the safety, effectiveness, and stability of the treatment units and systems based on the evaluation of acute toxicity, tumor response, and working ratio of the machine, respectively. Six patients, including liver cancer in three, prostate cancer in two, and lung cancer in one, were treated. There was no cessation of therapy owing to machine malfunction. Full courses of proton therapy consisting of 154 portals in all six patients were given exactly as scheduled. None of the patients experienced severe acute reactions of more than grade 3 according to NCI-CTC criteria. Tumor response one month post-treatment was evaluable in five of the six patients, and was CR in 1 (prostate cancer), PR in 2 (lung cancer: 1, liver cancer: 1), and NC in 2 (liver cancer: 2). These results indicate that our treatment units and systems are safe and reliable enough for proton irradiation to be used for several malignant tumors localized in the body. (author)

  7. Nuclear Astrophysics Data from Radioactive Beam Facilities. Final report

    International Nuclear Information System (INIS)

    Chen, Alan A.

    2008-01-01

    The scientific aims of this project have been the evaluation and dissemination of key nuclear reactions in nuclear astrophysics, with a focus on ones to be studied at new radioactive beam facilities worldwide. These aims were maintained during the entire funding period from 2003 - 2006. In the following, a summary of the reactions evaluated during this period is provided. Year 1 (2003-04): 21 Na(p,γ) 22 Mg and 18 Ne(α,p) 21 Na - The importance of the 21 Na(p,γ) 22 Mg and the 18 Ne(α,p) 21 Na reactions in models of exploding stars has been well documented: the first is connected to the production of the radioisotope 22 Na in nova nucleosynthesis, while the second is a key bridge between the Hot-CNO cycles and the rp-process in X-ray bursts. By the end of Summer 2004, our group had updated these reaction rates to include all published data up to September 2004, and cast the reaction rates into standard analytical and tabular formats with the assistance of Oak Ridge National Laboratory's computational infrastructure for reaction rates. Since September 2004, ongoing experiments on these two reactions have been completed, with our group's participation in both: 21 Na(p,γ) 22 Mg at the TRIUMF-ISAC laboratory (DRAGON collaboration), and 18Ne(α,p) 21 Na at Argonne National Laboratory (collaboration with Ernst Rehm, Argonne). The data from the former was subsequently published and included in our evaluation. Publication from the latter still awaits independent confirmation of the experimental results. Year 2 (2004-05): The 25Al(p,γ) 26 Si and 13 N(p,γ)14O reactions - For Year 2, we worked on evaluations of the 25 Al(p,γ) 26 Si and 13 N(p,γ) 14 O reactions, in accordance with our proposed deliverables and following similar standard procedures to those used in Year 1. The 25 Al(p,γ) 26 Si reaction is a key uncertainty in the understanding the origin of galactic 26 Al, a target radioisotope for gamma ray astronomy; the 13 N(p,γ) 14 O reaction in turn is the trigger

  8. Ion sources for initial use at the Holifield radioactive ion beam facility

    International Nuclear Information System (INIS)

    Alton, G.D.

    1994-01-01

    The Holifield Radioactive Ion Beam Facility (HRIBF) now under construction at the Oak Ridge National Laboratory will use the 25-MV tandem accelerator for the acceleration of radioactive ion beams to energies appropriate for research in nuclear physics; negative ion beams are, therefore, required for injection into the tandem accelerator. Because charge exchange is an efficient means for converting initially positive ion beams to negative ion beams, both positive and negative ion sources are viable options for use at the facility; the choice of the type of ion source will depend on the overall efficiency for generating the radioactive species of interest. A high-temperature version of the CERN-ISOLDE positive ion source has been selected and a modified version of the source designed and fabricated for initial use at the HRIBF because of its low emittance, relatively high ionization efficiencies and species versatility, and because it has been engineered for remote installation, removal and servicing as required for safe handling in a high-radiation-level ISOL facility. Prototype plasma-sputter negative ion sources and negative surfaceionization sources are also under design consideration for generating negative radioactive ion beams from high electron-affinity elements. A brief review of the HRIBF will be presented, followed by a detailed description of the design features, operational characteristics, ionization efficiencies, and beam qualities (emittances) of these sources

  9. Investigation on the neutron beam characteristics for boron neutron capture therapy with 3D and 2D transport calculations

    International Nuclear Information System (INIS)

    Kodeli, I.; Diop, C.M.; Nimal, J.C.

    1994-01-01

    In the framework of future Boron Neutron Capture Therapy (BNCT) experiments, where cells and animals irradiations are planned at the research reactor of Strasbourg University, the feasibility to obtain a suitable epithermal neutron beam is investigated. The neutron fluence and spectra calculations in the reactor are performed using the 3D Monte Carlo code TRIPOLI-3 and the 2D SN code TWODANT. The preliminary analysis of Al 2 O 3 and Al-Al 2 O 3 filters configurations are carried out in an attempt to optimize the flux characteristics in the beam tube facility. 7 figs., 7 refs

  10. Formation of a uniform ion beam using octupole magnets for BioLEIR facility at CERN

    Science.gov (United States)

    Amin, T.; Barlow, R.; Ghithan, S.; Roy, G.; Schuh, S.

    2018-04-01

    The possibility to transform the Low Energy Ion Ring (LEIR) accelerator at CERN into a multidisciplinary, biomedical research facility (BioLEIR) was investigated based on a request from the biomedical community. BioLEIR aims to provide a unique facility with a range of fully stripped ion beams (e.g. He, Li, Be, B, C, N, O) and energies suitable for multidisciplinary biomedical, clinically-oriented research. Two horizontal and one vertical beam transport lines have been designed for transporting the extracted beam from LEIR to three experimental end-stations. The vertical beamline was designed for a maximum energy of 75 MeV/u, while the two horizontal beamlines shall deliver up to a maximum energy of 440 MeV/u. A pencil beam of 4.3 mm FWHM (Full Width Half Maximum) as well as a homogeneous broad beam of 40 × 40 mm2, with a beam homogeneity better than ±4%, are available at the first horizontal (H1) irradiation point, while only a pencil beam is available at the second horizontal (H2) and vertical (V) irradiation points. The H1 irradiation point shall be used to conduct systematic studies of the radiation effect from different ion species on cell-lines. The H1 beamline was designed to utilize two octupole magnets which transform the Gaussian beam distribution at the target location into an approximately uniformly distributed rectangular beam. In this paper, we report on the multi-particle tracking calculations performed using MAD-X software suite for the H1 beam optics to arrive at a homogeneous broad beam on target using nonlinear focusing techniques, and on those to create a Gaussian pencil beam on target by adjusting quadrupoles strengths and positions.

  11. Experimental and Simulated Characterization of a Beam Shaping Assembly for Accelerator- Based Boron Neutron Capture Therapy (AB-BNCT)

    International Nuclear Information System (INIS)

    Burlon, Alejandro A.; Valda, Alejandro A.; Girola, Santiago; Minsky, Daniel M.; Kreiner, Andres J.

    2010-01-01

    In the frame of the construction of a Tandem Electrostatic Quadrupole Accelerator facility devoted to the Accelerator-Based Boron Neutron Capture Therapy, a Beam Shaping Assembly has been characterized by means of Monte-Carlo simulations and measurements. The neutrons were generated via the 7 Li(p, n) 7 Be reaction by irradiating a thick LiF target with a 2.3 MeV proton beam delivered by the TANDAR accelerator at CNEA. The emerging neutron flux was measured by means of activation foils while the beam quality and directionality was evaluated by means of Monte Carlo simulations. The parameters show compliance with those suggested by IAEA. Finally, an improvement adding a beam collimator has been evaluated.

  12. X-ray pencil beam facility for optics characterization

    Science.gov (United States)

    Krumrey, Michael; Cibik, Levent; Müller, Peter; Bavdaz, Marcos; Wille, Eric; Ackermann, Marcelo; Collon, Maximilien J.

    2010-07-01

    The Physikalisch-Technische Bundesanstalt (PTB) has used synchrotron radiation for the characterization of optics and detectors for astrophysical X-ray telescopes for more than 20 years. At a dedicated beamline at BESSY II, a monochromatic pencil beam is used by ESA and cosine Research since the end of 2005 for the characterization of novel silicon pore optics, currently under development for the International X-ray Observatory (IXO). At this beamline, a photon energy of 2.8 keV is selected by a Si channel-cut monochromator. Two apertures at distances of 12.2 m and 30.5 m from the dipole source form a pencil beam with a typical diameter of 100 μm and a divergence below 1". The optics to be investigated is placed in a vacuum chamber on a hexapod, the angular positioning is controlled by means of autocollimators to below 1". The reflected beam is registered at 5 m distance from the optics with a CCD-based camera system. This contribution presents design and performance of the upgrade of this beamline to cope with the updated design for IXO. The distance between optics and detector can now be 20 m. For double reflection from an X-ray Optical Unit (XOU) and incidence angles up to 1.4°, this corresponds to a vertical translation of the camera by 2 m. To achieve high reflectance at this angle even with uncoated silicon, a lower photon energy of 1 keV is available from a pair of W/B4C multilayers. For coated optics, a high energy option can provide a pencil beam of 7.6 keV radiation.

  13. Fermilab Test Beam Facility Annual Report FY17

    Energy Technology Data Exchange (ETDEWEB)

    Rominsky, M. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Schmidt, E. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Rivera, R. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Uplegger, L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Asaadi, J. [Univ. of Texas, Arlington, TX (United States); Raaf, J. L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Freeman, J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Price, J. [Univ. of Liverpool (United Kingdom); Casey, B. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Ehrlich, R. [Univ. of Virginia, Charlottesville, VA (United States); Belmont, R. [Univ. of Colorado, Boulder, CO (United States); Boose, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Conners, M. [Georgia State Univ., Atlanta, GA (United States); Haggerty, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hill, K. [Univ. of Colorado, Boulder, CO (United States); Hodges, A. [Georgia State Univ., Atlanta, GA (United States); Huang, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Kistenev, E. [Brookhaven National Lab. (BNL), Upton, NY (United States); Lajoie, J. [Iowa State Univ., Ames, IA (United States); Mannel, E. [Brookhaven National Lab. (BNL), Upton, NY (United States); Osborn, J. [Univ. of Michigan, Ann Arbor, MI (United States); Pontieri, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Purschke, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Sarsour, M. [Georgia State Univ., Atlanta, GA (United States); Sen, A. [Iowa State Univ., Ames, IA (United States); Skoby, M. [Univ. of Michigan, Ann Arbor, MI (United States); Stoll, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Toldo, F. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ujvari, B. [Debrecen Univ., Debrecen (Hungary); Woody, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ronzhin, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Hanagaki, K. [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Apresyan, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Bose, T. [Boston Univ., MA (United States); Canepa, A. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Demina, R. [Univ. of Rochester, NY (United States); Gershtein, Y. [Rutgers Univ., Piscataway, NJ (United States); Halkiadakis, E. [Rutgers Univ., Piscataway, NJ (United States); Haytmyradov, M. [Univ. of Iowa, Iowa City, IA (United States); Hazen, E. [Boston Univ., MA (United States); Hindrichs, O. [Univ. of Rochester, NY (United States); Korjenevski, S. [Univ. of Rochester, NY (United States); Nachtman, J. [Univ. of Iowa, Iowa City, IA (United States); Narain, M. [Brown Univ., Providence, RI (United States); Nash, K. [Rutgers Univ., Piscataway, NJ (United States); Onel, Y. [Univ. of Iowa, Iowa City, IA (United States); Osherson, M. [Rutgers Univ., Piscataway, NJ (United States); Rankin, D. [Boston Univ., MA (United States); Schneider, B. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Stone, B. [Rutgers Univ., Piscataway, NJ (United States); Metcalfe, J. [Argonne National Lab. (ANL), Argonne, IL (United States); Benoit, M. [Univ. of Geneva (Switzerland); Vicente, M. [Univ. of Geneva (Switzerland); di Bello, F. [Univ. of Geneva (Switzerland); Cavallaro, E. [Univ. Autonoma de Barcelona (Spain); Chakanov, S. [Argonne National Lab. (ANL), Argonne, IL (United States); Frizzell, D. [Univ. of Oklahoma, Norman, OK (United States); Kiehn, M. [Univ. of Geneva (Switzerland); Meng, L. [Univ. of Geneva (Switzerland); Miucci, A. [Univ. of Bern, Bern (Switzerland); Nodulman, L. [Argonne National Lab. (ANL), Argonne, IL (United States); Terzo, S. [Univ. Autonoma de Barcelona (Spain); Wang, Rui [Argonne National Lab. (ANL), Argonne, IL (United States); Weston, T. [Univ. of Oklahoma, Norman, OK (United States); Xie, Junqie [Argonne National Lab. (ANL), Argonne, IL (United States); Xu, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Zaffaroni, E. [Univ. of Geneva (Switzerland); Zhang, M. [Univ. of Illinois, Urbana, IL (United States); Argelles, C. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Axani, S. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Conrad, J. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Katori, T. [Queen Mary Univ. of London (United Kingdom); Noulai, M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Mandalia, S. [Queen Mary Univ. of London (United Kingdom); Sandstrom, P. [Univ. of Wisconsin, Madison, WI (United States); Kryemadhi, A. [Messiah College, Mechanicsburg, PA (United States); Barner, L. [Messiah College, Mechanicsburg, PA (United States); Grove, A. [Messiah College, Mechanicsburg, PA (United States); Mohler, J. [Messiah College, Mechanicsburg, PA (United States); Roth, A. [Messiah College, Mechanicsburg, PA (United States); Beuzekom, M. van [Nikhef National Inst. for Subatomic Physics, Amsterdam (Netherlands); Dall' Occo, E. [Nikhef National Inst. for Subatomic Physics, Amsterdam (Netherlands); Schindler, H. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Paley, J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Badgett, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Denisov, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Lukic, S. [Vinca Inst. of Nuclear Sciences, Belgrade (Serbia); Ujic, P. [Vinca Inst. of Nuclear Sciences, Belgrade (Serbia); Lebrun, P. L.G. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Fields, L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Christian, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Zaki, R. [Radboud Univ., Nijmegen (Netherlands)

    2018-01-23

    This Technical Memorandum (TM) summarizes the Fermilab Test Beam operations for FY2017. It is one of a series of annual publications intended to gather information in one place. In this case, the information concerns the individual experiments that ran at FTBF and are listed in Table 1. Each experiment section was prepared by the relevant authors, and was edited for inclusion in this summary.

  14. Design of multi-megawatt actively cooled beam dumps for the Neutral-Beam Engineering Test Facility

    International Nuclear Information System (INIS)

    Paterson, J.A.; Koehler, G.; Wells, R.P.

    1981-10-01

    The Neutral Beam Engineering Test Facility will test Neutral Beam Sources up to 170 keV, 65 Amps, with 30 second beam-on times. For this application actively cooled beam dumps for both the neutral and ionized particles will be required. The dumps will be able to dissipate a wide range of power density profiles by utilizing a standard modular panel design which is incorporated into a moveable support structure. The thermal hydraulic design of the panels permit the dissipation of 2 kW/cm 2 anywhere on the panel surface. The water requirements of the dumps are optimized by restricting the flow to panel sections where the heat flux falls short of the design value. The mechanical design of the beam-dump structures is described along with tests performed on a prototype panel. The prototype tests were performed on two different panel designs, one manufactured by Mc Donnell Douglas (MDAC) the other by United Technologies (UT). The dissipation capabilities of the panels were tested at the critical regions to verify their use in the beam dump assemblies

  15. Impact of Spot Size and Beam-Shaping Devices on the Treatment Plan Quality for Pencil Beam Scanning Proton Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Moteabbed, Maryam, E-mail: mmoteabbed@partners.org; Yock, Torunn I.; Depauw, Nicolas; Madden, Thomas M.; Kooy, Hanne M.; Paganetti, Harald

    2016-05-01

    Purpose: This study aimed to assess the clinical impact of spot size and the addition of apertures and range compensators on the treatment quality of pencil beam scanning (PBS) proton therapy and to define when PBS could improve on passive scattering proton therapy (PSPT). Methods and Materials: The patient cohort included 14 pediatric patients treated with PSPT. Six PBS plans were created and optimized for each patient using 3 spot sizes (∼12-, 5.4-, and 2.5-mm median sigma at isocenter for 90- to 230-MeV range) and adding apertures and compensators to plans with the 2 larger spots. Conformity and homogeneity indices, dose-volume histogram parameters, equivalent uniform dose (EUD), normal tissue complication probability (NTCP), and integral dose were quantified and compared with the respective PSPT plans. Results: The results clearly indicated that PBS with the largest spots does not necessarily offer a dosimetric or clinical advantage over PSPT. With comparable target coverage, the mean dose (D{sub mean}) to healthy organs was on average 6.3% larger than PSPT when using this spot size. However, adding apertures to plans with large spots improved the treatment quality by decreasing the average D{sub mean} and EUD by up to 8.6% and 3.2% of the prescribed dose, respectively. Decreasing the spot size further improved all plans, lowering the average D{sub mean} and EUD by up to 11.6% and 10.9% compared with PSPT, respectively, and eliminated the need for beam-shaping devices. The NTCP decreased with spot size and addition of apertures, with maximum reduction of 5.4% relative to PSPT. Conclusions: The added benefit of using PBS strongly depends on the delivery configurations. Facilities limited to large spot sizes (>∼8 mm median sigma at isocenter) are recommended to use apertures to reduce treatment-related toxicities, at least for complex and/or small tumors.

  16. Fast optimization and dose calculation in scanned ion beam therapy

    International Nuclear Information System (INIS)

    Hild, S.; Graeff, C.; Trautmann, J.; Kraemer, M.; Zink, K.; Durante, M.; Bert, C.

    2014-01-01

    Purpose: Particle therapy (PT) has advantages over photon irradiation on static tumors. An increased biological effectiveness and active target conformal dose shaping are strong arguments for PT. However, the sensitivity to changes of internal geometry complicates the use of PT for moving organs. In case of interfractionally moving objects adaptive radiotherapy (ART) concepts known from intensity modulated radiotherapy (IMRT) can be adopted for PT treatments. One ART strategy is to optimize a new treatment plan based on daily image data directly before a radiation fraction is delivered [treatment replanning (TRP)]. Optimizing treatment plans for PT using a scanned beam is a time consuming problem especially for particles other than protons where the biological effective dose has to be calculated. For the purpose of TRP, fast optimization and fast dose calculation have been implemented into the GSI in-house treatment planning system (TPS) TRiP98. Methods: This work reports about the outcome of a code analysis that resulted in optimization of the calculation processes as well as implementation of routines supporting parallel execution of the code. To benchmark the new features, the calculation time for therapy treatment planning has been studied. Results: Compared to the original version of the TPS, calculation times for treatment planning (optimization and dose calculation) have been improved by a factor of 10 with code optimization. The parallelization of the TPS resulted in a speedup factor of 12 and 5.5 for the original version and the code optimized version, respectively. Hence the total speedup of the new implementation of the authors' TPS yielded speedup factors up to 55. Conclusions: The improved TPS is capable of completing treatment planning for ion beam therapy of a prostate irradiation considering organs at risk in this has been overseen in the review process. Also see below 6 min

  17. Selection of carbon beam therapy: biophysical models of carbon beam therapy.

    Science.gov (United States)

    Matsufuji, Naruhiro

    2018-03-01

    Variation in the relative biological effectiveness (RBE) within the irradiation field of a carbon beam makes carbon-ion radiotherapy unique and advantageous in delivering the therapeutic dose to a deep-seated tumor, while sparing surrounding normal tissues. However, it is crucial to consider the RBE, not only in designing the dose distribution during treatment planning, but also in analyzing the clinical response retrospectively. At the National Institute of Radiological Sciences, the RBE model was established based on the response of human salivary gland cells. The response was originally handled with a linear-quadratic model, and later with a microdosimetric kinetic model. Retrospective analysis with a tumor-control probability model of non-small cell cancer treatment revealed a steep dose response in the tumor, and that the RBE of the tumor was adequately estimated using the model. A commonly used normal tissue complication probability model has not yet fully been accountable for the variable RBE of carbon ions; however, analysis of rectum injury after prostate cancer treatment suggested a highly serial-organ structure for the rectum, and a steep dose response similar to that observed for tumors.

  18. Impact of beam angle choice on pencil beam scanning breath-hold proton therapy for lung lesions

    DEFF Research Database (Denmark)

    Gorgisyan, Jenny; Perrin, Rosalind; Lomax, Antony J

    2017-01-01

    INTRODUCTION: The breath-hold technique inter alia has been suggested to mitigate the detrimental effect of motion on pencil beam scanned (PBS) proton therapy dose distributions. The aim of this study was to evaluate the robustness of incident proton beam angles to day-to-day anatomical variation...

  19. Commissioning and first results of the ITER-relevant negative ion beam test facility ELISE

    International Nuclear Information System (INIS)

    Franzen, P.; Heinemann, B.; Fantz, U.; Wünderlich, D.; Kraus, W.; Fröschle, M.; Martens, C.; Riedl, R.; Nocentini, R.; Masiello, A.; Ruf, B.; Schiesko, L.; Wimmer, C.

    2013-01-01

    The test facility ELISE which was constructed in the last three years at the Max-Planck-Institut für Plasmaphysik (IPP), Garching, is an important intermediate step of the development of the neutral beam system for ITER. ELISE allows gaining an early experience of the performance and operation of large RF driven sources for negative hydrogen ions and will give an important input for the commissioning and the design of the SPIDER and MITICA test facilities at Padua and the ITER neutral beam system. ELISE has gone recently into operation with first plasma and beam pulses. The experiments aim at the demonstration of an ion beam at the required parameters within 2 years of operation until end of 2014, the end of the service contract with F4E for the establishment and exploitation of ELISE

  20. A Micromegas Detector for Neutron Beam Imaging at the n_TOF Facility at CERN

    CERN Document Server

    Belloni, F; Berthoumieux, E; Calviani, M; Chiaveri, E; Colonna, N; Giomataris, Y; Guerrero, C; Gunsing, F; Iguaz, F J; Kebbiri, M; Pancin, J; Papaevangelou, T; Tsinganis, A; Vlachoudis, V; Altstadt, S; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Bečvář, F; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviño, F; Cano-Ott, D; Carrapiço, C; Cerutti, F; Chiaveri, E; Chin, M; Cortés, G; Corté-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Gurusamy, P; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Koehler, P; Kokkoris, M; Krtička, M; Kroll, J; Langer, C; Lederer, C; Leeb, H; Leong, L S; Losito, R; Manousos, A; Marganiec, J; Marítnez, T; Massimi, C; Mastinu, P F; Mastromarco, M; Meaze, M; Mendoza, E; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondalaers, W; Paradela, C; Pavlik, A; Perkowski, J; Plompen, A J M; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Roman, F; Rubbia, C; Sarmento, R; Schillebeeckx, P; Schmidt, S; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiss, C; Wright, T J; Žugec, P

    2014-01-01

    Micromegas (Micro-MEsh Gaseous Structure) detectors are gas detectors consisting of a stack of one ionization and one proportional chamber. A micromesh separates the two communicating regions, where two different electric fields establish respectively a charge drift and a charge multiplication regime. The n\\_TOF facility at CERN provides a white neutron beam (from thermal up to GeV neutrons) for neutron induced cross section measurements. These measurements need a perfect knowlodge of the incident neutron beam, in particular regarding its spatial profile. A position sensitive micromegas detector equipped with a B-10 based neutron/charged particle converter has been extensively used at the n\\_TOF facility for characterizing the neutron beam profile and extracting the beam interception factor for samples of different size. The boron converter allowed to scan the energy region of interest for neutron induced capture reactions as a function of the neutron energy, determined by the time of flight. Experimental ...

  1. First radioactive beams at ACCULINNA-2 facility and first proposed experiment

    Science.gov (United States)

    Bezbakh, A. A.; Beekman, W.; Chudoba, V.; Fomichev, A. S.; Golovkov, M. S.; Gorshkov, A. V.; Grigorenko, L. V.; Kaminski, G.; Krupko, S. A.; Mentel, M.; Nikolskii, E. Yu.; Parfenova, Yu. L.; Plucinski, P.; Sidorchuk, S. I.; Slepnev, R. S.; Sharov, P. G.; Ter-Akopian, G. M.; Zalewski, B.

    2018-04-01

    New fragment separator ACCULINNA-2 was installed at the primary beam line of the U-400M cyclotron in 2016. Recently, first radioactive ion beams were obtained. The design parameters of new facility were experimentally confirmed. Intensity, purity and transverse profile of several secondary beams at the final focal plane were studied. The intensities obtained for the secondary beams of 14B, 12Be, 9;11Li, 6;8He in the fragmentation reaction 15N (49.7 AMeV) + Be (2 mm) are in average 15 times higher in comparison to the ones produced at its forerunner ACCULINNA separator. The ACCULINNA-2 separator will become a backbone facility at the FLNR for the research in the field of light exotic nuclei in the vicinity of the nuclear drip lines. The planned first experiment, aimed for the observation of the 7H nucleus at ACCULINNA-2, is outlined.

  2. Physics and Technology for the Next Generation of Radioactive Ion Beam Facilities: EURISOL

    CERN Document Server

    Kadi, Y; Catherall, R; Giles, T; Stora, T; Wenander, F K

    2012-01-01

    Since the discovery of artificial radioactivity in 1935, nuclear scientists have developed tools to study nuclei far from stability. A major breakthrough came in the eighties when the first high energy radioactive beams were produced at Berkeley, leading to the discovery of neutron halos. The field of nuclear structure received a new impetus, and the major accelerator facilities worldwide rivalled in ingenuity to produce more intense, purer and higher resolution rare isotope beams, leading to our much improved knowledge and understanding of the general evolution of nuclear properties throughout the nuclear chart. However, today, further progress is hampered by the weak beam intensities of current installations which correlate with the difficulty to reach the confines of nuclear binding where new phenomena are predicted, and where the r-process path for nuclear synthesis is expected to be located. The advancement of Radioactive Ion Beam (RIB) science calls for the development of so-called next-generation facil...

  3. The proposed INEL intense slow positron source, beam line, and positron microscope facility

    International Nuclear Information System (INIS)

    Makowitz, H.; Denison, A.B.; Brown, B.

    1993-01-01

    A program is currently underway at the Idaho National Engineering Laboratory (INEL) to design and construct an Intense Slow Positron Beam Facility with an associated Positron Microscope. Positron beams have been shown to be valuable research tools and have potential application in industrial processing and nondestructive evaluation (microelectronics, etc.). The limit of resolution or overall usefulness of the technique has been limited because of lack of sufficient intensity. The goal of the INEL positron beam is ≥ 10 12 slow e+/s over a 0.03 cm diameter which represents a 10 3 to 10 4 advancement in beam current over existing beam facilities. The INEL is an ideal site for such a facility because of the nuclear reactors capable of producing intense positron sources and the personnel and facilities capable of handling high levels of radioactivity. A design using 58 Co with moderators and remoderators in conjunction with electrostatic positron beam optics has been reached after numerous computer code studies. Proof-of-principle electron tests have demonstrated the feasibility of the large area source focusing optics. The positron microscope development is occurring in conjunction with the University of Michigan positron microscope group. Such a Beam Facility and associated Intense Slow Positron Source (ISPS) can also be utilized for the generation and study of positron, and positron electron plasmas at ≤ 10 14 particles/cm 3 with plasma temperatures ranging from an eV to many keV, as well as an intense x-ray source via positron channeling radiation. The possibility of a tunable x-ray laser based on channeling positron radiation also exists. In this discussion the authors will present a progress report on various activities associated with the INEL ISPS

  4. Electron beam irradiation facility for low to high dose irradiation applications

    International Nuclear Information System (INIS)

    Petwal, V.C.; Wanmode, Yashwant; Verma, Vijay Pal; Bhisikar, Abhay; Dwivedi, Jishnu; Shrivastava, P.; Gupta, P.D.

    2013-01-01

    Electron beam based irradiation facilities are becoming more and more popular over the conventional irradiator facilities due to many inherent advantages such as tunability of beam energy, availability of radiation both in electron mode and X-ray mode, wide range of the dose rate, control of radiation from a ON-OFF switch and other safety related merits. A prototype experimental facility based on electron accelerator has been set-up at RRCAT to meet the low-dose, medium dose and high-dose requirements for radiation processing of food, agricultural and medical products. The facility can be operated in the energy range from 7-10 MeV at variable power level from 0.05-3 kW to meet the dose rate requirement of 100 Gy to kGy. The facility is also equipped with a Bremsstrahlung converter optimized for X-ray irradiation at 7.5 MV. Availability of dose delivery in wide range with precision control and measurement has made the facility an excellent tool for researchers interested in electron/X-ray beam irradiation. A precision dosimetry lab based on alanine EPR and radiochromic film dosimetry system have been established to characterize the radiation field and precise dose measurements. Electron beam scattering technique has been developed to achieve low dose requirement for EB irradiation of various seeds such as groundnut, wheat, soybeans, moong beans, black gram etc. for mutation related studies. This paper describes various features of the facility together with the dosimetric measurements carried out for qualification of the facility and recent irradiation experiments carried out using this facility. (author)

  5. External beam radiotherapy facilities in Ukraine. Trends and challenges

    International Nuclear Information System (INIS)

    Starenkiy, V.P.; Petrichenko, O.O.; Averyanova, L.O.

    2017-01-01

    The most important aspects of technological support of the radiation therapy of Ukraine are considered in accordance with the requirements of the IAEA. The reasons that influence the availability of radiotherapy for cancer patients in Ukraine are analyzed taking into account the experience of Grigoriev Institute for Medical Radiology of the National Academy of Medical Sciences of Ukraine.

  6. CYCLONE. Neutron therapy facility at Louvain-la-Neuve

    International Nuclear Information System (INIS)

    Meulders, J.P.; Saedeleer, G. de; Winant, M.; Wambersie, A.

    1979-01-01

    The neutrontherapy program at Louvain-la-Neuve is carried out with the cyclotron CYCLONE of the Catholic University. This isochronous variable energy cyclotron, produced by CSF (Corbeville, France), accelerates different types of charged particles; in particular, deuterons can be accelerated at energies ranging from 13 to 50 MeV. Neutrons used for therapeutic applications are produced by bombarding a thick (10 mm) water cooled, Beryllium target with 50 MeV deuterons. A beam current of about 5 μA is used for patient treatments, which produces dose rates of about 0,5 Gy/min at a target-skin-distance (TSD) of 157 cm. The treatment room, and related medical facilities, are located one level below the main level of the cyclotron. This permits the use of a vertical therapeutic neutron beam by bending the deuteron beam at 90 0 . This vertical beam appears to be more adequate for positioning the majority of the patients. The collimation system consists of a fixed shielding and of a series of interchangeable inserts. The inserts are cylindrical in shape; their height is 80 cm and their external diameter 40 cm. The proximal part (50 cm) is a mixture of iron (equivalent thickness 22 cm) and epoxy, and the distal part (30 cm) is a mixture (50%) of borax and epoxy. The emphasis is made on the radioprotection conditions. A series of measurements made in the treatment room and in the entry maze have shown that their special configuration provides a satisfactory protection of the staff. (author)

  7. SU-F-T-137: Out-Of-Beam Dose for a Compact Double-Scattering Proton Beam Therapy System

    Energy Technology Data Exchange (ETDEWEB)

    Islam, M; Ahmad, S; Jin, H [University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)

    2016-06-15

    Purpose: The out-of-beam dose is important for understanding the peripheral dose in radiation therapy. In proton radiotherapy, the study of out-of-beam dose is scarce and the treatment planning system (TPS) based on pencil beam algorithm cannot accurately predict the out-of-beam dose. This study investigates the out-of-beam dose for the single-room Mevion S250 double scattering proton therapy system using experimentally measured and treatment planning software generated data. The results are compared with those reported for conventional photon beam therapy. However, this study does not incorporate the neutron contribution in the scattered dose. Methods: A total of seven proton treatment plans were generated using Varian Eclipse TPS for three different sites (brain, lung, and pelvis) in an anthropomorphic phantom. Three field sizes of 5×5, 10×10, and 20×20 cm{sup 2} (lung only) with typical clinical range (13.3–22.8 g/cm{sup 2}) and modulation widths (5.3–14.0 g/cm{sup 2}) were used. A single beam was employed in each treatment plan to deliver a dose of 181.8 cGy (200.0 cGy (RBE)) to the selected target. The out-of-beam dose was measured at 2.0, 5.0, 10.0, and 15.0 cm from the beam edge in the phantom using a thimble chamber (PTW TN31010). Results: The out-of-beam dose generally increased with field size, range, and volume irradiated. For all the plans, the scattered dose sharply fell off with distance. At 2.0 cm, the out-of-beam dose ranged from 0.35% to 2.16% of the delivered dose; however, the dose was clinically negligible (<0.3%) at a distance of 5.0 cm and greater. In photon therapy, the slightly greater out-of-beam dose was reported (TG36; 4%, 2%, and 1% for 2.0, 5.0, and 10.0 cm, respectively, using 6 MV beam). Conclusion: The measured out-of-beam dose in proton therapy excluding neutron contribution was observed higher than the TPS calculated dose and comparable to that of photon beam therapy.

  8. Selection and design of ion sources for use at the Holifield radioactive ion beam facility

    International Nuclear Information System (INIS)

    Alton, G.D.; Haynes, D.L.; Mills, G.D.; Olsen, D.K.

    1994-01-01

    The Holifield Radioactive Ion Beam Facility now under construction at the Oak Ridge National Laboratory will use the 25 MV tandem accelerator for the acceleration of radioactive ion beams to energies appropriate for research in nuclear physics; negative ion beams are, therefore, required for injection into the tandem accelerator. Because charge exchange is an efficient means for converting initially positive ion beams to negative ion beams, both positive and negative ion sources are viable options for use at the facility. The choice of the type of ion source will depend on the overall efficiency for generating the radioactive species of interest. Although direct-extraction negative ion sources are clearly desirable, the ion formation efficiencies are often too low for practical consideration; for this situation, positive ion sources, in combination with charge exchange, are the logical choice. The high-temperature version of the CERN-ISOLDE positive ion source has been selected and a modified version of the source designed and fabricated for initial use at the facility because of its low emittance, relatively high ionization efficiencies, and species versatility, and because it has been engineered for remote installation, removal, and servicing as required for safe handling in a high-radiation-level ISOL facility. The source will be primarily used to generate ion beams from elements with intermediate to low electron affinities. Prototype plasma-sputter negative ion sources and negative surface-ionization sources are under design consideration for generating radioactive ion beams from high-electron-affinity elements. The design features of these sources and expected efficiencies and beam qualities (emittances) will be described in this report

  9. A facility for liquid-phase radiation experiments on heavy ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Stuglik, Z; Zvara, I; Yakushev, A B; Timokhin, S N [Flerov Lab. of Nuclear Reactions, Dubna (Russian Federation). Joint Inst. for Nuclear Research

    1994-05-01

    The facility for liquid-phase radiation experiments installed on the beam line of the U-400 cyclotron in the Flerov Laboratory of Nuclear Reactions, JINR, Dubna, is described. The accelerator provides intermediate energy (some 10 MeV/nucleon) beams of ions ranging from Li to Xe. Preliminary results on the radiolysis of the Fricke solution and malachite green in ethanol by {sup 11}B, {sup 24}Mg and {sup 40}Ca ions are presented. (author).

  10. Study of electron beam energy conversion at gyrocon-linear accelerator facility

    International Nuclear Information System (INIS)

    Karliner, M.M.; Makarov, I.G.; Ostreiko, G.N.

    2004-01-01

    A gyrocon together with the high-voltage 1.5 MeV accelerator ELIT-3A represents a power generator at 430 MHz serving for linear electron accelerator pulse driving. The facility description and results of calorimetric measurements of ELIT-3A electron beam power and accelerated beam at the end of accelerator are presented in the paper. The achieved energy conversion efficiency is about 55%

  11. Automatic beam position control at Los Alamos Spallation Radiation Effects Facility (LASREF)

    International Nuclear Information System (INIS)

    Oothoudt, M.; Pillai, C.; Zumbro, M.

    1997-01-01

    Historically the Los Alamos Spallation Radiation Effects Facility (LASREF) has used manual methods to control the position of the 800 kW, 800 MeV proton beam on targets. New experiments, however, require more stringent position control more frequently than can be done manually for long periods of time. Data from an existing harp is used to automatically adjust steering magnets to maintain beam position to required tolerances

  12. Research advances in proton beam therapy for hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    DAI Shuyang

    2013-10-01

    Full Text Available Hepatocellular carcinoma (HCC, one of the most common malignancies with high prevalence and mortality rate, usually results in poor prognosis and limited survival. A comprehensive analysis on the number and location of tumors, Child-Pugh grade, and Barcelona Clinic Liver Cancer stage will help the development of suitable treatment programs and improve prediction of prognosis. A majority of patients are complicated by cirrhosis, enlarged tumor, multiple lesions, vascular invasion, and even cancer embolus in the portal vein. With the growth of knowledge about the radiation tolerance of normal tissue and the advances in radiotherapy techniques, radiotherapy has become an important tool for step-down therapy and adjuvant therapy for liver cancer. Proton beam therapy (PBT is emerging as a novel radiotherapy for the management of HCC, which, benefiting from the effect of Bragg Peak from PBT, effectively decreases the toxicity of traditional radiotherapies to the liver and does little harm to the uninvolved liver tissue or the surrounding structures while intensifying the destruction in targeted malignant lesions. Furthermore, several previous studies on the treatment of HCC with PBT revealed excellent local control. The distinctive biophysical attributes of PBT in the treatment of HCC, as well as the available literature regarding clinical outcomes and toxicity of using PBT for HCC, are reviewed. Current evidence provides limited indications for PBT, which suggests that further study on the relationship between liver function and PBT is required to gain further insight into its indication and standardization.

  13. The Holifield Radioactive Ion Beams Facility (HRIBF) - getting ready to do experiments

    International Nuclear Information System (INIS)

    Shapira, D.; Lewis, T.A.

    1998-01-01

    The conversion of the HHIRF facility to a Radioactive Ion Beam facility started in 1994. In this ISOL type facility the Cyclotron has been re-fitted as a driver providing high intensity proton beams which react with the target from which the radioactive products are extracted and then accelerated in the Tandem Electrostatic Accelerator to the desired energy for nuclear science studies. Facilities for nuclear physics experiments are at different stages of development: A Recoil Mass Spectrometer (RMS) with a complement of detectors at the focal plane and around the target is used primarily for nuclear structure studies. A large recoil separator combining velocity and momentum selection, with its complement of focal plane detectors, will be dedicated to measurements relevant to nuclear astrophysics. The Enge Split Pole spectrograph is being re-fitted for operation in a gas filled mode, making it a more versatile tool for nuclear reaction studies. With the new experimental equipment being commissioned and the prospects of running experiments with low intensity radioactive beams a significant effort to develop equipment for beam diagnostics is underway. Some of the efforts and results in developing beam diagnostic tools will be described

  14. Charged particle therapy with mini-segmented beams

    Directory of Open Access Journals (Sweden)

    F. Avraham eDilmanian

    2015-12-01

    Full Text Available One of the fundamental attributes of proton therapy and carbon ion therapy is the ability of these charged particles to spare tissue distal to the targeted tumor. This significantly reduces normal tissue toxicity and has the potential to translate to a wider therapeutic index. Although, in general, particle therapy also reduces dose to the proximal tissues, particularly in the vicinity of the target, dose to the skin and to other very superficial tissues tends to be higher than that of megavoltage x-rays. The methods presented here, namely Interleaved carbon minibeams and Radiosurgery with arrays of proton and light ion minibeams, both utilize beams segmented into arrays of parallel minibeams of about 0.3 mm incident beam size. These minibeam arrays spare tissues, as demonstrated by synchrotron x-ray experiments. An additional feature of particle minibeams is their gradual broadening due to multiple Coulomb scattering as they penetrate tissues. In the case of interleaved carbon minibeams, which do not broaden much, two arrays of planar carbon minibeams that remain parallel at target depth, are aimed at the target from 90º angles and made to interleave at the target to produce a solid radiation field within the target. As a result the surrounding tissues are exposed only to individual carbon minibeam arrays and are therefore spared. The method was used in four-directional geometry at the NASA Space Radiation Laboratory to ablate a 6.5-mm target in a rabbit brain at a single exposure with 40 Gy physical absorbed dose. Contrast-enhanced magnetic resonance imaging and histology six month later showed very focal target necrosis with nearly no damage to the surrounding brain. As for minibeams of protons and light ions, for which the minibeam broadening is substantial, measurements at MD Anderson Cancer Center in Houston, Texas, and Monte Carlo simulations showed that the broadening minibeams will merge with their neighbors at a certain tissue depth

  15. Characterization of Dosimetry of the BMRR Horizontal Thimble Tubes and Broad Beam Facility.

    Energy Technology Data Exchange (ETDEWEB)

    Hu,J.P.; Reciniello, R.N.; Holden, N.E.

    2008-05-05

    The Brookhaven Medical Research Reactor was a 5 mega-watt, light-water cooled and heavy-graphite moderated research facility. It has two shutter-equipped treatment rooms, three horizontally extended thimble tubes, and an ex-core broad beam facility. The three experimental thimbles, or activation ports, external to the reactor tank were designed for several uses, including the investigations on diagnostic and therapeutic methods using radioactive isotopes of very short half-life, the analysis of radiation exposure on tissue-equivalent materials using a collimated neutron beam, and the evaluation of dose effects on biological cells to improve medical treatment. At the broad beam facility where the distribution of thermal neutrons was essential uniform, a wide variety of mammalian whole-body exposures were studied using animals such as burros or mice. Also studied at the broad beam were whole-body phantom experiments, involving the use of a neutron or photon beam streaming through a screen to obtain the flux spectrum suitable for dose analysis on the sugar-urea-water mixture, a tissue-equivalent material. Calculations of the flux and the dose at beam ports based on Monte Carlo particle-transport code were performed, and measurements conducted at the same tally locations were made using bare or cadmium-covered gold foils. Analytical results, which show good agreement with measurement data, are presented in the paper.

  16. Target irradiation facility and targetry development at 160 MeV proton beam of Moscow linac

    CERN Document Server

    Zhuikov, B L; Konyakhin, N A; Vincent, J

    1999-01-01

    A facility has been built and successfully operated with the 160 MeV proton beam of Moscow Meson factory LINAC, Institute for Nuclear Research (INR) of Russian Academy of Science, Troitsk. The facility was created for various isotope production goals as well as for fundamental nuclear investigations at high intensity beam (100 mu A and more). An important part of the facility targetry system is a high-intensity beam monitoring collimator device. Measurements of the temperature distribution between collimator sectors, cooling water flow and temperature, and the beam current, provide an opportunity to compute beam losses and beam position. The target holder design allows easy insertion by manipulator and simultaneous bombardment of several different targets of various types and forms, and variation of proton energy on each target over a wide range below 160 MeV. The main target utilized for commercial sup 8 sup 2 Sr isotope production is metallic rubidium in a stainless-steel container. A regular wet chemistry ...

  17. Preliminary shielding estimates for the proposed Oak Ridge National Laboratory (ORNL) Radioactive Ion Beam Facility (RIBF)

    International Nuclear Information System (INIS)

    Johnson, J.O.; Gabriel, T.A.; Lillie, R.A.

    1996-01-01

    The Oak Ridge National Laboratory (ORNL) has proposed designing and implementing a new target-ion source for production and injection of negative radioactive ion beams into the Hollifield tandem accelerator. This new facility, referred to as the Radioactive Ion Beam Facility (RIBF), will primarily be used to advance the scientific communities' capabilities for performing state-of-the-art cross-section measurements. Beams of protons or other light, stable ions from the Oak Ridge Isochronous Cyclotron (ORIC) will be stopped in the RIBF target ion source and the resulting radioactive atoms will be ionized, charge exchanged, accelerated, and injected into the tandem accelerator. The ORIC currently operates with proton energies up to 60 MeV and beam currents up to 100 microamps with a maximum beam power less than 2.0 kW. The proposed RIBF will require upgrading the ORIC to generate proton energies up to 200 MeV and beam currents up to 200 microamps for optimum performance. This report summarizes the results of a preliminary one-dimensional shielding analysis of the proposed upgrade to the ORIC and design of the RIBF. The principal objective of the shielding analysis was to determine the feasibility of such an upgrade with respect to existing shielding from the facility structure, and additional shielding requirements for the 200 MeV ORIC machine and RIBF target room

  18. Physics at a future Neutrino Factory and super-beam facility

    International Nuclear Information System (INIS)

    Bandyopadhyay, A; Choubey, S; Gandhi, R; Goswami, S; Roberts, B L; Bouchez, J; Antoniadis, I; Ellis, J; Giudice, G F; Schwetz, T; Umasankar, S; Karagiorgi, G; Aguilar-Arevalo, A; Conrad, J M; Shaevitz, M H; Pascoli, S; Geer, S; Campagne, J E; Rolinec, M; Blondel, A

    2009-01-01

    The conclusions of the Physics Working Group of the International Scoping Study of a future Neutrino Factory and super-beam facility (the ISS) are presented. The ISS was carried out by the international community between NuFact05, (the 7th International Workshop on Neutrino Factories and Super-beams, Laboratori Nazionali di Frascati, Rome, 21-26 June 2005) and NuFact06 (Ivine, CA, 24-30 August 2006). The physics case for an extensive experimental programme to understand the properties of the neutrino is presented and the role of high-precision measurements of neutrino oscillations within this programme is discussed in detail. The performance of second-generation super-beam experiments, beta-beam facilities and the Neutrino Factory are evaluated and a quantitative comparison of the discovery potential of the three classes of facility is presented. High-precision studies of the properties of the muon are complementary to the study of neutrino oscillations. The Neutrino Factory has the potential to provide extremely intense muon beams and the physics potential of such beams is discussed in the final section of the report.

  19. Initial electron-beam characterizations for the Los Alamos APEX Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lumpkin, A.H.; Feldman, R.B.; Apgar, S.A.; Feldman, D.W.; O' Shea, P.G. (Los Alamos National Lab., NM (United States)); Fiorito, R.B.; Rule, D.W. (Naval Surface Warfare Center, Silver Spring, MD (United States))

    1991-01-01

    The ongoing upgrade of the Los Alamos Free-Electron Laser (FEL) Facility involves the addition of a photoelectric injector (PEI) and acceleration capability to about 40 MeV. The electron-beam and high-speed diagnostics provide key measurements of charge, beam position and profile, divergence emittance, energy (centroid, spread, slew, and extraction efficiency), micropulse duration, and phase stability. Preliminary results on the facility include optical transition radiation interferometer measurements of divergence (1 to 2 mrad), FEL extraction efficiency (0.6 {plus minus} 0.2%), and drive laser phase stability (< 2 ps (rms)). 10 refs.

  20. Initial electron-beam characterizations for the Los Alamos APEX Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lumpkin, A.H.; Feldman, R.B.; Apgar, S.A.; Feldman, D.W.; O`Shea, P.G. [Los Alamos National Lab., NM (United States); Fiorito, R.B.; Rule, D.W. [Naval Surface Warfare Center, Silver Spring, MD (United States)

    1991-12-31

    The ongoing upgrade of the Los Alamos Free-Electron Laser (FEL) Facility involves the addition of a photoelectric injector (PEI) and acceleration capability to about 40 MeV. The electron-beam and high-speed diagnostics provide key measurements of charge, beam position and profile, divergence emittance, energy (centroid, spread, slew, and extraction efficiency), micropulse duration, and phase stability. Preliminary results on the facility include optical transition radiation interferometer measurements of divergence (1 to 2 mrad), FEL extraction efficiency (0.6 {plus_minus} 0.2%), and drive laser phase stability (< 2 ps [rms]). 10 refs.

  1. Measuring Dirac CP-violating phase with intermediate energy beta beam facility

    Science.gov (United States)

    Bakhti, P.; Farzan, Y.

    2014-02-01

    Taking the established nonzero value of , we study the possibility of extracting the Dirac CP-violating phase by a beta beam facility with a boost factor . We compare the performance of different setups with different baselines, boost factors, and detector technologies. We find that an antineutrino beam from He decay with a baseline of km has a very promising CP-discovery potential using a 500 kton water Cherenkov detector. Fortunately this baseline corresponds to the distance between FermiLAB to Sanford underground research facility in South Dakota.

  2. Prospects for exotic beam facilities in North America

    CERN Document Server

    Nolen, J A

    2002-01-01

    There are several nuclear physics laboratories in North America that have on-going research using energetic and stopped radioactive beams. These include the large ISOL-type programs ISAC at TRIUMF and HRIBF at Oak Ridge and the in-flight fragmentation program at the NSCL of Michigan State University. There are also smaller, more specialized, programs using a variety of techniques at the 88-inch cyclotron of Berkeley, ATLAS at Argonne, the Cyclotron Institute of Texas A&M University, the Nuclear Structure Laboratory at Notre Dame University, and the Nuclear Structure Laboratory at SUNY/Stony Brook. There are also three projects on the horizon in North America for new capabilities in both the near term and more distant future. The intensities of the in-flight fragment beams at the NSCL will be increased dramatically very soon as the Coupled Cyclotron Project will be completed and commissioned for research by mid-2001. A new project, ISAC-II, has been approved in Canada. For the longer term, the United State...

  3. Present and future colliding beam facilities at SLAC

    International Nuclear Information System (INIS)

    Wiedemann, H.

    1977-07-01

    In April 1972, the 3-GeV electron positron storage ring, SPEAR, was put into operation at the end of the linear accelerator at Stanford. By the recent discoveries in high energy physics the value of electron-positron storage rings for high energy physics has been clearly demonstrated. This development certainly encouraged the relatively early funding of the new electron-positron storage ring, PEP, at SLAC. In addition to its role as a particle physics research tool, SPEAR has been and remains a priceless model or prototype for larger storage rings like PEP. A few of the recent observations in SPEAR which have important implications to the design of PEP are described. Although the PEP design follows closely the SPEAR concept in many respects, it has its own distinctive and important features which are discussed in detail. Topics discussed include synchrotron-betatron resonances, beam losses, beam bunching, PEP design luminosity and energy, chromaticity correction in PEP, and the high energy cabability of PEP

  4. Ion chambers compliance results of Brazilian radiation therapy facilities.

    Science.gov (United States)

    Joana, G; Salata, C; Leal, P; Vasconcelos, R; Couto, N do; Teixeira, F C; Soares, A D; Santini, E S; Gonçalves, M

    2018-03-01

    The Brazilian Nuclear Energy Commission (cnen) has been making a constant effort to keep up to date with international standards and national needs to strengthen the status of radiological protection of the country. The guidelines related to radiation therapy facilities have been revised in the last five years in order to take into consideration the most relevant aspects of the growing technology as well as to mitigate the accidents or incidents observed in practice. Hence, clinical dosimeters have gained special importance in this matter. In the present work, we discuss the effectiveness of regulation and inspections to the enforcement of instrument calibration accuracy for the improvement of patient dosimetry and quality control. As a result, we observed that the number of calibrated instruments, mainly well chambers, is increasing each year. The same behavior is observed for instruments employed in technologically advanced radiation treatments such as intensity modulated radiotherapy, volumetric therapy and stereotatic radiosurgery. We ascribe this behavior to the new regulation.

  5. New developments of 11C post-accelerated beams for hadron therapy and imaging

    Science.gov (United States)

    Augusto, R. S.; Mendonca, T. M.; Wenander, F.; Penescu, L.; Orecchia, R.; Parodi, K.; Ferrari, A.; Stora, T.

    2016-06-01

    Hadron therapy was first proposed in 1946 and is by now widespread throughout the world, as witnessed with the design and construction of the CNAO, HIT, PROSCAN and MedAustron treatment centres, among others. The clinical interest in hadron therapy lies in the fact that it delivers precision treatment of tumours, exploiting the characteristic shape (the Bragg peak) of the energy deposition in the tissues for charged hadrons. In particular, carbon ion therapy is found to be biologically more effective, with respect to protons, on certain types of tumours. Following an approach tested at NIRS in Japan [1], carbon ion therapy treatments based on 12C could be combined or fully replaced with 11C PET radioactive ions post-accelerated to the same energy. This approach allows providing a beam for treatment and, at the same time, to collect information on the 3D distributions of the implanted ions by PET imaging. The production of 11C ion beams can be performed using two methods. A first one is based on the production using compact PET cyclotrons with 10-20 MeV protons via 14N(p,α)11C reactions following an approach developed at the Lawrence Berkeley National Laboratory [2]. A second route exploits spallation reactions 19F(p,X)11C and 23Na(p,X)11C on a molten fluoride salt target using the ISOL (isotope separation on-line) technique [3]. This approach can be seriously envisaged at CERN-ISOLDE following recent progresses made on 11C+ production [4] and proven post-acceleration of pure 10C3/6+ beams in the REX-ISOLDE linac [5]. Part of the required components is operational in radioactive ion beam facilities or commercial medical PET cyclotrons. The driver could be a 70 MeV, 1.2 mA proton commercial cyclotron, which would lead to 8.1 × 10711C6+ per spill. This intensity is appropriate using 11C ions alone for both imaging and treatment. Here we report on the ongoing feasibility studies of such approach, using the Monte Carlo particle transport code FLUKA [6,7] to simulate

  6. New developments of {sup 11}C post-accelerated beams for hadron therapy and imaging

    Energy Technology Data Exchange (ETDEWEB)

    Augusto, R.S., E-mail: r.s.augusto@cern.ch [European Organization for Nuclear Research – CERN, 1211 Geneva 23 (Switzerland); Ludwig Maximilians – University of Munich, Munich (Germany); Mendonca, T.M.; Wenander, F. [European Organization for Nuclear Research – CERN, 1211 Geneva 23 (Switzerland); Penescu, L. [MedAustron GmbH, Wiener Neustadt (Austria); Orecchia, R. [CNAO – Centro Nazionale di Adroterapia Oncologica per il trattamento dei tumori, Pavia (Italy); Parodi, K. [Ludwig Maximilians – University of Munich, Munich (Germany); Ferrari, A.; Stora, T. [European Organization for Nuclear Research – CERN, 1211 Geneva 23 (Switzerland)

    2016-06-01

    Hadron therapy was first proposed in 1946 and is by now widespread throughout the world, as witnessed with the design and construction of the CNAO, HIT, PROSCAN and MedAustron treatment centres, among others. The clinical interest in hadron therapy lies in the fact that it delivers precision treatment of tumours, exploiting the characteristic shape (the Bragg peak) of the energy deposition in the tissues for charged hadrons. In particular, carbon ion therapy is found to be biologically more effective, with respect to protons, on certain types of tumours. Following an approach tested at NIRS in Japan [1], carbon ion therapy treatments based on {sup 12}C could be combined or fully replaced with {sup 11}C PET radioactive ions post-accelerated to the same energy. This approach allows providing a beam for treatment and, at the same time, to collect information on the 3D distributions of the implanted ions by PET imaging. The production of {sup 11}C ion beams can be performed using two methods. A first one is based on the production using compact PET cyclotrons with 10–20 MeV protons via {sup 14}N(p,α){sup 11}C reactions following an approach developed at the Lawrence Berkeley National Laboratory [2]. A second route exploits spallation reactions {sup 19}F(p,X){sup 11}C and {sup 23}Na(p,X){sup 11}C on a molten fluoride salt target using the ISOL (isotope separation on-line) technique [3]. This approach can be seriously envisaged at CERN-ISOLDE following recent progresses made on {sup 11}C{sup +} production [4] and proven post-acceleration of pure {sup 10}C{sup 3/6+} beams in the REX-ISOLDE linac [5]. Part of the required components is operational in radioactive ion beam facilities or commercial medical PET cyclotrons. The driver could be a 70 MeV, 1.2 mA proton commercial cyclotron, which would lead to 8.1 × 10{sup 711}C{sup 6+} per spill. This intensity is appropriate using {sup 11}C ions alone for both imaging and treatment. Here we report on the ongoing feasibility

  7. Developing an expert system to control a beam line at the Los Alamos Meson Physics Facility

    International Nuclear Information System (INIS)

    Clearwater, S.H.; Papcun, G.; Clark, D.A.

    1985-01-01

    High energy particle experiments require an accelerator as a source of high energy particles. To increase the productivity of an accelerator facility, we wish to develop an expert system to control beam lines. Expert Systems are a branch of Artificial Intelligence where a computer program performs tasks requiring human expertise. Unlike most expert systems we have a physical model underlying our beam line and this model can be used with the expert system to improve performance. The development of the expert system will lead to an increased understanding of the beam line as well as the possibility of state-of-the-art expert system building

  8. Proton-beam window design for a transmutation facility operating with a liquid lead target

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, C.; Lypsch, F.; Lizana, P. [Institute for Safety Research and Reactor Technology, Juelich (Germany)] [and others

    1995-10-01

    The proton beam target of an accelerator-driven transmutation facility can be designed as a vertical liquid lead column. To prevent lead vapor from entering the accelerator vacuum, a proton-beam window has to separate the area above the lead surface from the accelerator tube. Two radiation-cooled design alternatives have been investigated which should withstand a proton beam of 1.6 GeV and 25 mA. Temperature calculations based on energy deposition calculations with the Monte Carlo code HETC, stability analysis and spallation-induced damage calculations have been performed showing the applicability of both designs.

  9. Concepts for the magnetic design of the MITICA neutral beam test facility ion accelerator.

    Science.gov (United States)

    Chitarin, G; Agostinetti, P; Marconato, N; Marcuzzi, D; Sartori, E; Serianni, G; Sonato, P

    2012-02-01

    The megavolt ITER injector concept advancement neutral injector test facility will be constituted by a RF-driven negative ion source and by an electrostatic Accelerator, designed to produce a negative Ion with a specific energy up to 1 MeV. The beam is then neutralized in order to obtain a focused 17 MW neutral beam. The magnetic configuration inside the accelerator is of crucial importance for the achievement of a good beam efficiency, with the early deflection of the co-extracted and stripped electrons, and also of the required beam optic quality, with the correction of undesired ion beamlet deflections. Several alternative magnetic design concepts have been considered, comparing in detail the magnetic and beam optics simulation results, evidencing the advantages and drawbacks of each solution both from the physics and engineering point of view.

  10. The JANNUS Saclay facility: A new platform for materials irradiation, implantation and ion beam analysis

    Energy Technology Data Exchange (ETDEWEB)

    Pellegrino, S., E-mail: stephanie.pellegrino@cea.fr [CEA, INSTN, UEPTN, Laboratoire JANNUS, F-91191 Gif-sur-Yvette (France); Trocellier, P.; Miro, S.; Serruys, Y.; Bordas, E.; Martin, H. [CEA, DEN, Service de Recherches de Metallurgie Physique, Laboratoire JANNUS, F-91191 Gif-sur-Yvette (France); Chaabane, N.; Vaubaillon, S. [CEA, INSTN, UEPTN, Laboratoire JANNUS, F-91191 Gif-sur-Yvette (France); Gallien, J.P.; Beck, L. [CEA, DEN, Service de Recherches de Metallurgie Physique, Laboratoire JANNUS, F-91191 Gif-sur-Yvette (France)

    2012-02-15

    The third accelerator of the multi-ion irradiation platform JANNUS (Joint Accelerators for Nanosciences and NUclear Simulation), a 6SDH-2 Pelletron from National Electrostatic Corporation, Middleton was installed at Saclay in October 2009. The first triple beam irradiation combining Fe, He and H ion beams has been performed in March 2010. In the first part of this paper, we give a technical description of the triple beam facility, its performances and experimental capabilities. Typically, damage dose up to 100 dpa can be reached in 10 h irradiation with heavy ion beams, with or without simultaneous bombardment by protons, helium-4 ions or any other heavy ion beam. In the second part of this paper, we illustrate some IBA results obtained after irradiation and implantation experiments.

  11. The rapid cycling synchrotron of the Eurisol / Beta-Beam facility

    International Nuclear Information System (INIS)

    Lachaize, A.

    2008-09-01

    In order to ask for physicians requests, some neutrinos facilities are under studies to produce pure, intense, well collimated neutrinos beams with a well determined energy spectrum. One of them, the Beta-Beam project, is based on neutrinos production by radioactive ion beams decay after acceleration. The thesis is focused on one step of the complex, namely the low energy ring required for accumulation and injection of ion beams between the post-acceleration linac of the EURISOL complex (dedicated complex for radioactive ion beam production) and the CERN PS. After the description of the EURISOL complex and the Beta-Beam complex, a description of charged particles beams transport formalism is given. Then, in the second part, studies on the definition and the optimisation of the ring are given, starting by optical structure then different simulations concerning beam dynamics, i.e. multiturn injection, synchronous acceleration with beam losses localization and intensity, fast extraction, chromaticity with eddy currents correction and space charge effects. Finally, a preliminary technical design of the RCS main magnets is proposed. (author)

  12. Construction of the neutron beam facility at Australia's OPAL research reactor

    International Nuclear Information System (INIS)

    Kennedy, Shane J.

    2006-01-01

    Australia's new research reactor, OPAL, has been designed principally for neutron beam science and radioisotope production. It has a capacity for 18 neutron beam instruments, located at the reactor face and in a neutron guide hall. The neutron beam facility features a 20 l liquid deuterium cold neutron source and cold and thermal supermirror neutron guides. Nine neutron beam instruments are under development, of which seven are scheduled for completion in early 2007. The project is approaching the hot-commissioning stage, when criticality will be demonstrated. Installation of the neutron beam transport system and neutron beam instruments in the neutron guide hall and at the reactor face is underway, and the path to completion of this project is relatively clear. This paper will outline the key features of the OPAL reactor, and will describe the neutron beam facility in particular. The status of the construction and a forecast of the program to completion, including commissioning and commencement of routine operation in 2007 will also be discussed

  13. A new ion beam facility based on a 3 MV Tandetron™ at IFIN-HH, Romania

    Science.gov (United States)

    Burducea, I.; Straticiuc, M.; Ghiță, D. G.; Moșu, D. V.; Călinescu, C. I.; Podaru, N. C.; Mous, D. J. W.; Ursu, I.; Zamfir, N. V.

    2015-09-01

    A 3 MV Tandetron™ accelerator system has been installed and commissioned at the "Horia Hulubei" National Institute for Physics and Nuclear Engineering - IFIN-HH, Măgurele, Romania. The main purpose of this machine is to strengthen applied nuclear physics research ongoing in our institute for more than four decades. The accelerator system was developed by High Voltage Engineering Europa B.V. (HVE) and comprises three high energy beam lines. The first beam line is dedicated to ion beam analysis (IBA) techniques: Rutherford Backscattering Spectrometry - RBS, Nuclear Reaction Analysis - NRA, Particle Induced X-ray and γ-ray Emission - PIXE and PIGE and micro-beam experiments - μ-PIXE. The second beam line is dedicated to high energy ion implantation experiments and the third beam line was designed mainly for nuclear cross-sections measurements used in nuclear astrophysics. A unique feature, the first time in operation at an accelerator facility is the Na charge exchange canal (CEC), which is used to obtain high intensity beams of He- of at least 3 μA. The results of the acceptance tests demonstrate the huge potential of this new facility in various fields, from IBA to radiation hardness studies and from medical or environmental applications to astrophysics. The main features of the accelerator are presented in this paper.

  14. Present and future colliding beam facilities at SLAC

    International Nuclear Information System (INIS)

    Wiedemann, H.

    1977-01-01

    Present state of the 4.1 GeV electron-positron storage ring SPEAR is described. The most important limitations on performance in SPEAR, such as synchrotron-betatron resonances, higher-order mode losses are outlined. Active bunch lengthener was outstalled in SPEAR to reduce the losses. Experiments on the bunch lengthening observed in SPEAR showed that the lengthening mechanism results from bunch instabilities due to the bunch interaction with the environment. SPEAR performance experience provided with effective prototype for directing the design of PEP-the 18 GeV positron-electron storage ring with designed luminosity of 10 32 cm -2 s -1 . Procurements and construction of PEP components are in full swing. The first beam is expeted to go around in the storage ring by October 1979

  15. MedAustron - Ion-Beam Therapy and Research Center

    International Nuclear Information System (INIS)

    Schreiner, Thomas; Seemann, Rolf

    2015-01-01

    MedAustron is a synchrotron-based light-ion beam therapy center for cancer treatment as well as for clinical and non-clinical research, currently in the commissioning phase in Wiener Neustadt, Austria. Recently, the first proton beam was transported successfully to one of the four irradiation rooms. Whilst the choice of basic machine parameters was driven by medical requirements, i.e. 60 MeV protons and 120 MeV/A to 400 MeV/A carbon ions, the accelerator complex design was also optimized to offer flexibility for research operation. The potential of the synchrotron is being exploited to increase the maximum proton energy far beyond the medical needs to up to 800 MeV, for experimental physics applications, mainly in the areas of proton scattering and detector research. The accelerator layout allows for the installation of up to four ion source-spectrometer units, to provide various ion types besides the clinical used protons and carbon ions. Besides experimental physics, the two main non-clinical research disciplines are medical radiation physics and radiation biology. To decouple research and medical operation, a dedicated irradiation room for non-clinical research was included providing the installation of different experiments. In addition, several labs have been equipped with appropriate devices for preparing and analyzing radio-biological samples. This presentation gives a status overview over the whole project and highlights the non-clinical research opportunities at MedAustron. (Author)

  16. Accuracy of robotic patient positioners used in ion beam therapy

    International Nuclear Information System (INIS)

    Nairz, Olaf; Winter, Marcus; Heeg, Peter; Jäkel, Oliver

    2013-01-01

    In this study we investigate the accuracy of industrial six axes robots employed for patient positioning at the Heidelberg Ion Beam Therapy Center. In total 1018 patient setups were monitored with a laser tracker and subsequently analyzed. The measurements were performed in the two rooms with a fixed horizontal beam line. Both, the 3d translational errors and the rotational errors around the three table axes were determined. For the first room the 3d error was smaller than 0.72 mm in 95 percent of all setups. The standard deviation of the rotational errors was at most 0.026° for all axes. For the second room Siemens implemented an improved approach strategy to the final couch positions. The 95 percent quantile of the 3d error could in this room be reduced to 0.53 mm; the standard deviation of the rotational errors was also at most 0.026°. Robots are very flexible tools for patient positioning in six degrees of freedom. This study proved that the robots are able to achieve clinically acceptable accuracy in real patient setups, too

  17. Beam calorimetry at the large negative ion source test facility ELISE: Experimental setup and latest results

    International Nuclear Information System (INIS)

    Nocentini, Riccardo; Bonomo, Federica; Ricci, Marina; Pimazzoni, Antonio; Fantz, Ursel; Heinemann, Bernd; Riedl, Rudolf; Wünderlich, Dirk

    2016-01-01

    Highlights: • ELISE is the first step in the European roadmap for the development of the ITER NBI. • Several beam diagnostic tools have been installed, the latest results are presented. • A gaussian fit procedure has been implemented to characterize the large ion beam. • Average beamlet group inhomogeneity is maximum 13%, close to the ITER target of 10%. • Beam divergence measured by calorimeter agrees with the BES measurements within 30%. - Abstract: The test facility ELISE is the first step within the European roadmap for the development of the ITER NBI system. ELISE is equipped with a 1 × 0.9 m"2 radio frequency negative ion source (half the ITER source size) and an ITER-like 3-grid extraction system which can extract an H"− or D"− beam for 10 s every 3 min (limited by available power supplies) with a total acceleration voltage of up to 60 kV. In the beam line of ELISE several beam diagnostic tools have been installed with the aim to evaluate beam intensity, divergence and uniformity. A copper diagnostic calorimeter gives the possibility to measure the beam power density profile with high resolution. The measurements are performed by an IR micro-bolometer camera and 48 thermocouples embedded in the calorimeter. A gaussian fit procedure has been implemented in order to characterize the large negative ion beam produced by ELISE. The latest results obtained from the beam calorimetry at ELISE show that the average beamlet group inhomogeneity is maximum 13%. The measured beam divergence agrees with the one measured by beam emission spectroscopy within 30%.

  18. Control system specification for a cyclotron and neutron therapy facility

    International Nuclear Information System (INIS)

    Jacky, J.; Risler, R.; Kalet, I.; Wootton, P.; Barke, A.; Brossard, S.; Jackson, R.

    1991-01-01

    It is usually considered an essential element of good practice in engineering to produce a specification for a system before building it. However, it has been found to be quite difficult to produce useful specifications of large software systems. The authors have nearly completed a comprehensive specification for the computer control system of a cyclotron and treatment facility that provides particle beams for cancer treatments with fast neutrons, production of medical isotopes, and physics experiments. They describe the control system as thoroughly as is practical using standard technical English, supplemented by tables, diagrams, and some algebraic equations. This specification comprises over 300 single-spaced pages. A more precise and compact specification might be achieved by making greater use of formal mathematical notations instead of English. They have begun work on a formal specification of the system, using the Z and Petri net notations

  19. The design, fabrication and operation of the mechanical systems for the Neutral Beam Engineering Test Facility

    International Nuclear Information System (INIS)

    Patterson, J.A.; Fong, M.; Koehler, G.W.; Low, W.; Purgalis, P.; Wells, R.P.

    1983-01-01

    The Neutral Beam Engineering Test Facility (NBETF) at the Lawrence Berkeley Laboratory (LBL) is a National Test Facility used to develop long pulse Neutral Beam Sources. The Facility will test sources up to 120 keV, 50 A, with 30 s beam-on times with a 10% duty factor. For this application, an actively cooled beam dump is required and one has been constructed capable of dissipating a wide range of power density profiles. The flexibility of the design is achieved by utilizing a standard modular panel design which is incorporated into a moveable support structure comprised of eight separately controllable manipulator assemblies. The thermal hydraulic design of the panels permits the dissipation of 2 kW/cm 2 anywhere on the panel surface. The cooling water requirements of the actively cooled dump system are provided by the closed loop Primary High Pressure Cooling Water System. To minimize the operating costs of continuously running this high power system, a variable speed hydraulic drive is used for the main pump. During beam pulses, the pump rotates at high speed, then cycles to low speed upon completion of the beam shot. A unique neutralizer design has been installed into the NBETF beamline. This is a gun-drilled moveable brazed assembly which provides continuous armoring of the beamline near the source. The unit penetrates the source mounting valve during operation and retracts to permit the valve to close as needed. The beamline also has an inertially cooled duct calorimeter assembly. This assembly is a moveable hinged matrix of copper plates that can be used as a beam stop up to pulse lengths of 50 ms. The beamline is also equipped with many beam scraper plates of differing detail design and dissipation capabilities

  20. The intensity feedback system at Heidelberg Ion-Beam Therapy Centre

    Energy Technology Data Exchange (ETDEWEB)

    Schoemers, Christian, E-mail: christian.schoemers@med.uni-heidelberg.de; Feldmeier, Eike; Naumann, Jakob; Panse, Ralf; Peters, Andreas; Haberer, Thomas

    2015-09-21

    At Heidelberg Ion-Beam Therapy Centre (HIT), more than 2500 tumour patients have been treated with charged particle beams since 2009 using the raster scanning method. The tumour is irradiated slice-by-slice, each slice corresponding to a different beam energy. For the particle dose of each raster point the pre-irradiation by more distal slices has to be considered. This leads to highly inhomogeneous dose distributions within one iso-energy slice. The particles are extracted from the synchrotron via transverse RF knock-out. A pure feed forward control cannot take into account fluence inhomogeneities or deal with intensity fluctuations. So far, fluctuations have been counteracted by a reduced scanning velocity. We now added a feedback loop to the extraction system. The dose monitoring ionisation chambers in front of the patient have been coupled to the extraction device in the synchrotron. Characterization and implementation of the intensity feedback system into the HIT facility is described here. By its implementation the treatment time has been reduced by 10% in average.

  1. 21 CFR 892.5710 - Radiation therapy beam-shaping block.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Radiation therapy beam-shaping block. 892.5710 Section 892.5710 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... block. (a) Identification. A radiation therapy beam-shaping block is a device made of a highly...

  2. MOSFET dosimetry of the radiation therapy microbeams at the European synchrotron radiation facility

    International Nuclear Information System (INIS)

    Rozenfeld, A.; Lerch, M.

    2002-01-01

    Full text: We have developed an innovative on-line MOSFET readout system for use in the quality assurance of radiation treatment beams. Recently the system has found application in areas where excellent spatial resolution is also a requirement in the quality assurance process, for example IMRT, and microbeam radiation therapy. The excellent spatial resolution is achieved by using a quadruple RADFET TM chip in 'edge on' mode. In developing this approach we have found that the system can be utilised to determine any error in the beam profile measurements due to misalignment of RADFET with respect to the radiation beam or microbeam. Using this approach will ensure that the excellent spatial resolution of the RADFET used in 'edge-on' mode is fully utilised. In this work we report on dosimetry measurements performed at the microbeam radiation therapy beamline located at the European Synchrotron Radiation Facility. The synchrotron planar array microbeam with size 10-30 μm and pitch ∼200 μm has found an important application in microbeam radiation therapy (MRT) of brain tumours in infants for whom other kinds of radiotherapy are inadequate and/or unsafe. The radiation damage from an array of parallel microbeams correlates strongly with the range of peak-valley dose ratios (PVDR), ie, the range of the ratio of the absorbed dose to tissue directly in line with the mid-plane of the microbeam to that in the mid-plane between adjacent microbeams. Novel physical dosimetry of the microbeams using the online MOSFET reader system will be presented. Comparison of the experimental results with both GaF film measurements and Monte Carlo computer-simulated dosimetry are described here for selected points in the peak and valley regions of a microbeam-irradiated tissue phantom

  3. Definitive proton beam radiation therapy for inoperable gastric cancer

    International Nuclear Information System (INIS)

    Shibuya, Susumu; Takase, Yasuhiro; Aoyagi, Hiroyuki; Orii, Kazuo; Sharma, N.; Iwasaki, Yoji; Tsujii, Hirohiko; Tsujii, Hiroshi.

    1991-01-01

    Proton beam radiation therapy using 250 MeV protons was carried out on two patients with early gastric cancer (T1, N0, M0). One patient was an 85-year-old man with early gastric cancer of type IIa + IIc. The other one was a 70-year-old man with early gastric cancer of type IIc. In both cases histological examination of biopsy specimens showed differential adenocarcinoma; distant metastasis was not found by other examinations. Both patients were considered inoperable due to their poor cardiac and/or respiratory functions. Therefore, it was decided to treat them by definitive proton irradiation, delivering total doses of 86 Gy and 83 Gy, respectively. In both patients, skin erythema that did not require any special treatment was found in the irradiation field. Hematobiological examinations did not show any abnormality. Although endoscopic examination at two years after irradiation in the former case and at seven months in the latter case showed persistent gastric ulcer at the site of the cancerous lesions, cancer cells were not found histologically. Therefore, we concluded that proton irradiation therapy was useful for inoperable early gastric cancers. (author)

  4. Lessons from shielding retrofits at the LAMPF/LANSCE/PSR accelerator, beam lines and target facilities

    International Nuclear Information System (INIS)

    Macek, R.J.

    1994-01-01

    The experience in the past 7 years to improve the shielding and radiation control systems at the Los Alamos Meson Physics Facility (LAMPF) and the Manuel Lujan Jr. Neutron Scattering Center (LANSCE) provides important lessons for the design of radiation control systems at future, high beam power proton accelerator facilities. Major issues confronted and insight gained in developing shielding criteria and in the use of radiation interlocks are discussed. For accelerators and beam lines requiring hands-on-maintenance, our experience suggests that shielding criteria based on accident scenarios will be more demanding than criteria based on routinely encountered beam losses. Specification and analysis of the appropriate design basis accident become all important. Mitigation by active protection systems of the consequences of potential, but severe, prompt radiation accidents has been advocated as an alternate choice to shielding retrofits for risk management at both facilities. Acceptance of active protection systems has proven elusive primarily because of the difficulty in providing convincing proof that failure of active systems (to mitigate the accident) is incredible. Results from extensive shielding assessment studies are presented including data from experimental beam spill tests, comparisons with model estimates, and evidence bearing on the limitations of line-of-sight attenuation models in complex geometries. The scope and significant characteristics of major shielding retrofit projects at the LAMPF site are illustrated by the project to improve the shielding beneath a road over a multiuse, high-intensity beam line (Line D)

  5. Design, fabrication and operation of the mechanical systems for the Neutral Beam Engineering Test Facility

    International Nuclear Information System (INIS)

    Paterson, J.A.; Biagi, L.A.; Fong, M.; Koehler, G.W.; Low, W.; Purgalis, P.; Wells, R.P.

    1983-12-01

    The Neutral Beam Engineering Test Facility (NBETF) at Lawrence Berkeley Laboratory (LBL) is a National Test Facility used to develop long pulse Neutral Beam Sources. The Facility will test sources up to 120 keV, 50 A, with 30 s beam-on times with a 10% duty factor. For this application, an actively cooled beam dump is required and one has been constructed capable of dissipating a wide range of power density profiles. The flexibility of the design is achieved by utilizing a standard modular panel design which is incorporated into a moveable support structure comprised of eight separately controllable manipulator assemblies. A unique neutralizer design has been installed into the NBETF beamline. This is a gun-drilled moveable brazed assembly which provides continuous armoring of the beamline near the source. The unit penetrates the source mounting valve during operation and retracts to permit the valve to close as needed. The beamline is also equpped with many beam scraper plates of differing detail design and dissipation capabilities

  6. Producing National Ignition Facility (NIF)-quality beams on the Nova and Beamlet lasers

    International Nuclear Information System (INIS)

    Widmayer, C.C.; Auerbach, J.M.; Ehrlich, R.B.

    1996-08-01

    The Nova and Beamlet lasers were used to simulate the beam propagation conditions that will be encountered during the National Ignition Facility operation. Perturbation theory predicts that there is a 5mm scale length propagation mode that experiences large nonlinear power growth. This mode was observed in the tests. Further tests have confirmed that this mode can be suppressed with improved spatial filtering

  7. Facility for the testing of the TFTR prototype neutral beam injector

    Energy Technology Data Exchange (ETDEWEB)

    Haughian, J.M.

    1977-07-01

    The design of the prototype neutral beam injection system for TFTR is nearing completion at the Lawrence Livermore Laboratory. This paper describes some of the features of the facility at the Lawrence Berkeley Laboratory where this prototype will be assembled and tested.

  8. Facility for the testing of the TFTR prototype neutral beam injector

    International Nuclear Information System (INIS)

    Haughian, J.M.

    1977-07-01

    The design of the prototype neutral beam injection system for TFTR is nearing completion at the Lawrence Livermore Laboratory. This paper describes some of the features of the facility at the Lawrence Berkeley Laboratory where this prototype will be assembled and tested

  9. Physics at a future Neutrino Factory and super-beam facility

    NARCIS (Netherlands)

    Bandyopadhyay, A.; Choubey, S.; Gandhi, R.; Goswami, S.; Roberts, B. L.; Bouchez, J.; Antoniadis, I.; Ellis, J.; Giudice, G. F.; Schwetz, T.; Umasankar, S.; Karagiorgi, G.; Aguilar-Arevalo, A.; Conrad, J. M.; Shaevitz, M. H.; Pascoli, S.; Geer, S.; Campagne, J. E.; Rolinec, M.; Blondel, A.; Campanelli, M.; Kopp, J.; Lindner, M.; Peltoniemi, J.; Dornan, P. J.; Long, K.; Matsushita, T.; Rogers, C.; Uchida, Y.; Dracos, M.; Whisnant, K.; Casper, D.; Chen, Mu-Chun; Popov, B.; Aysto, J.; Marfatia, D.; Okada, Y.; Sugiyama, H.; Jungmann, K.; Lesgourgues, J.; Zisman, M.; Tortola, M. A.; Friedland, A.; Davidson, S.; Antusch, S.; Biggio, C.; Donini, A.; Fernandez-Martinez, E.; Gavela, B.; Maltoni, M.

    2009-01-01

    The conclusions of the Physics Working Group of the International Scoping Study of a future Neutrino Factory and super-beam facility (the ISS) are presented. The ISS was carried out by the international community between NuFact05, (the 7th International Workshop on Neutrino Factories and

  10. Intraoperative electron beam radiation therapy (IOEBRT) for carcinoma of the exocrine pancreas

    International Nuclear Information System (INIS)

    Dobelbower, R.R. Jr.; Konski, A.A.; Merrick, H.W. III; Bronn, D.G.; Schifeling, D.; Kamen, C.

    1991-01-01

    The abdominal cavities of 50 patients were explored in a specially constructed intraoperative radiotherapy operating amphitheater at the Medical College of Ohio. Twenty-six patients were treated with intraoperative and postoperative precision high dose external beam therapy, 12 with intraoperative irradiation but no external beam therapy, and 12 with palliative surgery alone. All but two patients completed the postoperative external beam radiation therapy as initially prescribed. The median survival time for patients treated with palliative surgery alone was 4 months, and that for patients treated with intraoperative radiotherapy without external beam therapy was 3.5 months. Patients undergoing intraoperative irradiation and external beam radiation therapy had a median survival time of 10.5 months. Four patients died within 30 days of surgery and two patients died of gastrointestinal hemorrhage 5 months posttreatment

  11. Phase space measurements at non-accessible point on the beam path of an accelerator facility

    International Nuclear Information System (INIS)

    Hassan, A.

    2004-01-01

    The optimization of beam lines for particles extracted from accelerator facilities requires the knowledge of beam parameters. A method for the measurement of phase space and beam intensity distribution is represented. This method depends on the setting of quadrupole lenses that allows the imaging of beam profiles at arbitrary positions along the beam path on the same multi-wire proportional chamber, where the intensity distribution can be evaluated. The necessary focusing powers for a certain imaging task are calculated in a thin lens approximation. The corresponding focusing power for thick quadrupole lenses are calculated using the PC transport program. A comparison of the calculated focusing powers for thin and thick lenses reveals deviations at the highest field strengths, due to saturation effect. The position of the beam waist in normal and angular space is directly calculated and visualized. The horizontal and vertical waist positions are found to be rather independent of the beam energy. Extensive calculation was done to study the effect of a reduced aperture on the maximum beam emittances aa x and aa y of the extracted particles. The main result shows that the maximum emittance passing through depends on the waist distant and the diameter of the reduced aperture. (orig.)

  12. Monitoring the electron beam position at the TESLA test facility free electron laser

    Energy Technology Data Exchange (ETDEWEB)

    Kamps, T

    2000-06-14

    The operation of a free electron laser working in the Self Amplified Spontaneous Emission mode (SASE FEL) requires the electron trajectory to be aligned with very high precision in overlap with the photon beam. In order to ensure this overlap, one module of the SASE FEL undulator at the TESLA Test Facility (TTF) is equipped with a new type of waveguide beam position monitor (BPM). Four waveguides are arranged symmetrically around the beam pipe, each channel couples through a small slot to the electromagnetic beam field. The induced signal depends on the beam intensity and on the transverse beam position in terms of beam-to-slot distance. With four slot--waveguide combinations a linear position sensitive signal can be achieved, which is independent of the beam intensity. The signals transduced by the slots are transferred by ridged waveguides through an impedance matching stage into a narrowband receiver tuned to 12 GHz. The present thesis describes design, tests, and implementation of this new type of BPM. (orig.)

  13. Profile of European proton and carbon ion therapy centers assessed by the EORTC facility questionnaire.

    Science.gov (United States)

    Weber, Damien C; Abrunhosa-Branquinho, André; Bolsi, Alessandra; Kacperek, Andrzej; Dendale, Rémi; Geismar, Dirk; Bachtiary, Barbara; Hall, Annika; Heufelder, Jens; Herfarth, Klaus; Debus, Jürgen; Amichetti, Maurizio; Krause, Mechthild; Orecchia, Roberto; Vondracek, Vladimir; Thariat, Juliette; Kajdrowicz, Tomasz; Nilsson, Kristina; Grau, Cai

    2017-08-01

    We performed a survey using the modified EORTC Facility questionnaire (pFQ) to evaluate the human, technical and organizational resources of particle centers in Europe. The modified pFQ consisted of 235 questions distributed in 11 sections accessible on line on an EORTC server. Fifteen centers from 8 countries completed the pFQ between May 2015 and December 2015. The average number of patients treated per year and per particle center was 221 (range, 40-557). The majority (66.7%) of centers had pencil beam or raster scanning capability. Four (27%) centers were dedicated to eye treatment only. An increase in the patients-health professional FTE ratio was observed for eye tumor only centers when compared to other centers. All centers treated routinely chordomas/chondrosarcomas, brain tumors and sarcomas but rarely breast cancer. The majority of centers treated pediatric cases with particles. Only a minority of the queried institutions treated non-static targets. As the number of particle centers coming online will increase, the experience with this treatment modality will rise in Europe. Children can currently be treated in these facilities in a majority of cases. The majority of these centers provide state of the art particle beam therapy. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Investigating proton emitters at the limits of stability with radioactive beams from the Oak Ridge facility

    Energy Technology Data Exchange (ETDEWEB)

    Toth, K.S. [Oak Ridge National Lab., TN (United States); Batchelder, J.C.; Zganjar, E.F. [Louisiana State Univ., Baton Rouge, LA (United States); Bingham, C.R.; Wauters, J. [Tennessee Univ., Knoxville, TN (United States); Davinson, T.; MacKenzie, J.A.; Woods, P.J. [Edinburgh Univ. (United Kingdom)

    1996-10-01

    By using beams from the Holifield Radioactive Ion Beam Facility at ORNL, it should be possible to identify many new ground-state proton emitters in the mass region from Sn to Pb. In these investigations nuclei produced in fusion-evaporation reactions will be separated from incident ions and dispersed in mass/charge with a recoil mass separator and then implanted into a double-sided Si strip detector for study of proton (and {alpha}-particle) radioactivity. This paper summarizes data presently extant on proton emitters and then focuses on tests and initial experiments that will be carried out with stable beams and with radioactive ions as they are developed at the Oak Ridge facility.

  15. Hadron-therapy beam monitoring: Towards a new generation of ultra-thin p-type silicon strip detectors

    International Nuclear Information System (INIS)

    Bouterfa, M.; Aouadi, K.; Bertrand, D.; Olbrechts, B.; Delamare, R.; Raskin, J. P.; Gil, E. C.; Flandre, D.

    2011-01-01

    Hadron-therapy has gained increasing interest for cancer treatment especially within the last decade. System commissioning and quality assurance procedures impose to monitor the particle beam using 2D dose measurements. Nowadays, several monitoring systems exist for hadron-therapy but all show a relatively high influence on the beam properties: indeed, most devices consist of several layers of materials that degrade the beam through scattering and energy losses. For precise treatment purposes, ultra-thin silicon strip detectors are investigated in order to reduce this beam scattering. We assess the beam size increase provoked by the Multiple Coulomb Scattering when passing through Si, to derive a target thickness. Monte-Carlo based simulations show a characteristic scattering opening angle lower than 1 mrad for thicknesses below 20 μm. We then evaluated the fabrication process feasibility. We successfully thinned down silicon wafers to thicknesses lower than 10 μm over areas of several cm 2 . Strip detectors are presently being processed and they will tentatively be thinned down to 20 μm. Moreover, two-dimensional TCAD simulations were carried out to investigate the beam detector performances on p-type Si substrates. Additionally, thick and thin substrates have been compared thanks to electrical simulations. Reducing the pitch between the strips increases breakdown voltage, whereas leakage current is quite insensitive to strips geometrical configuration. The samples are to be characterized as soon as possible in one of the IBA hadron-therapy facilities. For hadron-therapy, this would represent a considerable step forward in terms of treatment precision. (authors)

  16. The Clatterbridge high-energy neutron therapy facility: specification and performance

    International Nuclear Information System (INIS)

    Bonnett, D.E.; Blake, S.W.; Shaw, J.E.; Bewley, D.K.

    1988-01-01

    A high energy neutron therapy facility has been installed at the Douglas Cyclotron Centre, Clatterbridge Hospital Merseyside, to extend M.R.C. clinical trials of fast neutrons. The neutron beam is produced by bombarding a beryllium target with 62 MeV protons. The target is isocentrically mounted with potential for 360 0 rotation, with a fully variable collimator, giving a range of rectilinear field sizes from 5 cm x 5 cm to 30 cm x 30 cm. Basic neutron beam data including output, field flatness, penumbra and depth-dose data have been measured. For a 10 cm x 10 cm field, 50% depth dose occurs at 16.2 cm in water and output is 1.63 cGy μ A -1 min -1 at maximum dose depth. Effectiveness of the target shielding and neutron-induced radioactivity in the treatment head were also measured. It is concluded that the equipment meets design specifications and fully satisfies criticisms of earlier neutron therapy equipment. A full radiation survey showed that radiation levels present no significant staff hazard. (UK)

  17. Preliminary design of safety and interlock system for indian test facility of diagnostic neutral beam

    International Nuclear Information System (INIS)

    Tyagi, Himanshu; Soni, Jignesh; Yadav, Ratnakar; Bandyopadhyay, Mainak; Rotti, Chandramouli; Gahlaut, Agrajit; Joshi, Jaydeep; Parmar, Deepak; Bansal, Gourab; Pandya, Kaushal; Chakraborty, Arun

    2016-01-01

    Highlights: • Indian Test Facility being built to characterize DNB for ITER delivery. • Interlock system required to safeguard the investment incurred in building the facility and protecting ITER deliverable components. • Interlock levels upto 3IL-3 identified. • Safety instrumented system for occupational safety being designed. Safety I&C functions of SIL-2 identified. • The systems are based on ITER PIS and PSS design guidelines. - Abstract: Indian Test Facility (INTF) is being built in Institute For Plasma Research to characterize Diagnostic Neutral Beam in co-operation with ITER Organization. INTF is a complex system which consists of several plant systems like beam source, gas feed, vacuum, cryogenics, high voltage power supplies, high power RF generators, mechanical systems and diagnostics systems. Out of these, several INTF components are ITER deliverable, that is, beam source, beam line components and power supplies. To ensure successful operation of INTF involving integrated operation of all the constituent plant systems a matured Data Acquisition and Control System (DACS) is required. The INTF DACS is based on CODAC platform following on PCDH (Plant Control Design Handbook) guidelines. The experimental phases involve application of HV power supplies (100 KV) and High RF power (∼800 KW) which will produce energetic beam of maximum power 6MW within the facility for longer durations. Hence the entire facility will be exposed tohigh heat fluxes and RF radiations. To ensure investment protection and to provide occupational safety for working personnel a matured Safety and Interlock system is required for INTF. The Safety and Interlock systems are high-reliability I&C systems devoted completely to the specific functions. These systems will be separate from the conventional DACS of INTF which will handle the conventional control and acquisition functions. Both, the Safety and Interlock systems are based on IEC 61511 and IEC 61508 standards as

  18. Preliminary design of safety and interlock system for indian test facility of diagnostic neutral beam

    Energy Technology Data Exchange (ETDEWEB)

    Tyagi, Himanshu, E-mail: htyagi@iter-india.org [ITER-India, Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Soni, Jignesh [Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Yadav, Ratnakar; Bandyopadhyay, Mainak; Rotti, Chandramouli [ITER-India, Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Gahlaut, Agrajit [Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Joshi, Jaydeep; Parmar, Deepak [ITER-India, Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India); Bansal, Gourab; Pandya, Kaushal; Chakraborty, Arun [Institute For Plasma Research, Bhat, Gandhinagar, Gujarat (India)

    2016-11-15

    Highlights: • Indian Test Facility being built to characterize DNB for ITER delivery. • Interlock system required to safeguard the investment incurred in building the facility and protecting ITER deliverable components. • Interlock levels upto 3IL-3 identified. • Safety instrumented system for occupational safety being designed. Safety I&C functions of SIL-2 identified. • The systems are based on ITER PIS and PSS design guidelines. - Abstract: Indian Test Facility (INTF) is being built in Institute For Plasma Research to characterize Diagnostic Neutral Beam in co-operation with ITER Organization. INTF is a complex system which consists of several plant systems like beam source, gas feed, vacuum, cryogenics, high voltage power supplies, high power RF generators, mechanical systems and diagnostics systems. Out of these, several INTF components are ITER deliverable, that is, beam source, beam line components and power supplies. To ensure successful operation of INTF involving integrated operation of all the constituent plant systems a matured Data Acquisition and Control System (DACS) is required. The INTF DACS is based on CODAC platform following on PCDH (Plant Control Design Handbook) guidelines. The experimental phases involve application of HV power supplies (100 KV) and High RF power (∼800 KW) which will produce energetic beam of maximum power 6MW within the facility for longer durations. Hence the entire facility will be exposed tohigh heat fluxes and RF radiations. To ensure investment protection and to provide occupational safety for working personnel a matured Safety and Interlock system is required for INTF. The Safety and Interlock systems are high-reliability I&C systems devoted completely to the specific functions. These systems will be separate from the conventional DACS of INTF which will handle the conventional control and acquisition functions. Both, the Safety and Interlock systems are based on IEC 61511 and IEC 61508 standards as

  19. SU-E-T-400: Evaluation of Shielding and Activation at Two Pencil Beam Scanning Proton Facilities

    International Nuclear Information System (INIS)

    Remmes, N; Mundy, D; Classic, K; Beltran, C; Kruse, J; Herman, M; Stoker, J; Nelson, K; Bues, M

    2015-01-01

    Purpose: To verify acceptably low dose levels around two newly constructed identical pencil beam scanning proton therapy facilities and to evaluate accuracy of pre-construction shielding calculations. Methods: Dose measurements were taken at select points of interest using a WENDI-2 style wide-energy neutron detector. Measurements were compared to pre-construction shielding calculations. Radiation badges with neutron dose measurement capabilities were worn by personnel and also placed at points throughout the facilities. Seven neutron and gamma detectors were permanently installed throughout the facility, continuously logging data. Potential activation hazards have also been investigated. Dose rates near water tanks immediately after prolonged irradiation have been measured. Equipment inside the treatment room and accelerator vault has been surveyed and/or wipe tested. Air filters from air handling units, sticky mats placed outside of the accelerator vault, and water samples from the magnet cooling water loops have also been tested. Results: All radiation badges have been returned with readings below the reporting minimum. Measurements of mats, air filters, cooling water, wipe tests and surveys of equipment that has not been placed in the beam have all come back at background levels. All survey measurements show the analytical shielding calculations to be conservative by at least a factor of 2. No anomalous events have been identified by the building radiation monitoring system. Measurements of dose rates close to scanning water tanks have shown dose rates of approximately 10 mrem/hr with a half-life less than 5 minutes. Measurements around the accelerator show some areas with dose rates slightly higher than 10 mrem/hr. Conclusion: The shielding design is shown to be adequate. Measured dose rates are below those predicted by shielding calculations. Activation hazards are minimal except in certain very well defined areas within the accelerator vault and for objects

  20. The CBS-The Most Cost Effective and High Performance Carbon Beam Source Dedicated for a New Generation Cancer Therapy

    CERN Document Server

    Kumada, Masayuki; Leivichev, E B; Parkhomchuk, Vasily; Podgorny, Fedor; Rastigeev, Sergey; Reva, Vladimir B; Skrinsky, Aleksander Nikolayevich; Vostrikov, Vladimir

    2005-01-01

    A Carbon ion beam is a superior tool to x-rays or a proton beam in both physical and biological doses in treating a cancer. A Carbon beam has an advantage in treating radiation resistant and deep-seated tumors. Its radiological effect is of a mitotic independent nature. These features improve hypofractionation, typically reducing the number of irradiations per patient from 35 to a few. It has been shown that a superior QOL(Quality Of Life) therapy is possible by a carbon beam.The only drawback is its high cost. Nevertheless, tens of Prefectures and organizations are eagerly considering the possibility of having a carbon ion therapy facility in Japan. Germany, Austria, Italy, China, Taiwan and Korea also desire to have one.A carbon beam accelerator of moderate cost is about 100 Million USD. With the "CBS" design philosophy, which will be described in this paper, the cost could be factor of 2 or 3 less, while improving its performance more than standard designs. Novel extraction techniques, a new approach to a ...

  1. Compendium of Neutron Beam Facilities for High Precision Nuclear Data Measurements

    International Nuclear Information System (INIS)

    2014-07-01

    The recent advances in the development of nuclear science and technology, demonstrating the globally growing economy, require highly accurate, powerful simulations and precise analysis of the experimental results. Confidence in these results is still determined by the accuracy of the atomic and nuclear input data. For studying material response, neutron beams produced from accelerators and research reactors in broad energy spectra are reliable and indispensable tools to obtain high accuracy experimental results for neutron induced reactions. The IAEA supports the accomplishment of high precision nuclear data using nuclear facilities in particular, based on particle accelerators and research reactors around the world. Such data are essential for numerous applications in various industries and research institutions, including the safety and economical operation of nuclear power plants, future fusion reactors, nuclear medicine and non-destructive testing technologies. The IAEA organized and coordinated the technical meeting Use of Neutron Beams for High Precision Nuclear Data Measurements, in Budapest, Hungary, 10–14 December 2012. The meeting was attended by participants from 25 Member States and three international organizations — the European Organization for Nuclear Research (CERN), the Joint Research Centre (JRC) and the Organisation for Economic Co-operation and Development (OECD) Nuclear Energy Agency (OECD/NEA). The objectives of the meeting were to provide a forum to exchange existing know-how and to share the practical experiences of neutron beam facilities and associated instrumentation, with regard to the measurement of high precision nuclear data using both accelerators and research reactors. Furthermore, the present status and future developments of worldwide accelerator and research reactor based neutron beam facilities were discussed. This publication is a summary of the technical meeting and additional materials supplied by the international

  2. Compendium of Neutron Beam Facilities for High Precision Nuclear Data Measurements. Annex: Individual Reports

    International Nuclear Information System (INIS)

    2014-07-01

    The recent advances in the development of nuclear science and technology, demonstrating the globally growing economy, require highly accurate, powerful simulations and precise analysis of the experimental results. Confidence in these results is still determined by the accuracy of the atomic and nuclear input data. For studying material response, neutron beams produced from accelerators and research reactors in broad energy spectra are reliable and indispensable tools to obtain high accuracy experimental results for neutron induced reactions. The IAEA supports the accomplishment of high precision nuclear data using nuclear facilities in particular, based on particle accelerators and research reactors around the world. Such data are essential for numerous applications in various industries and research institutions, including the safety and economical operation of nuclear power plants, future fusion reactors, nuclear medicine and non-destructive testing technologies. The IAEA organized and coordinated the technical meeting Use of Neutron Beams for High Precision Nuclear Data Measurements, in Budapest, Hungary, 10–14 December 2012. The meeting was attended by participants from 25 Member States and three international organizations — the European Organization for Nuclear Research (CERN), the Joint Research Centre (JRC) and the Organisation for Economic Co-operation and Development (OECD) Nuclear Energy Agency (OECD/NEA). The objectives of the meeting were to provide a forum to exchange existing know-how and to share the practical experiences of neutron beam facilities and associated instrumentation, with regard to the measurement of high precision nuclear data using both accelerators and research reactors. Furthermore, the present status and future developments of worldwide accelerator and research reactor based neutron beam facilities were discussed. This publication is a summary of the technical meeting and additional materials supplied by the international

  3. Radiation protection metrology at a high-energy neutron therapy facility

    International Nuclear Information System (INIS)

    Bonnett, D.E.; Sherwin, A.G.; More, B.R.

    1991-01-01

    A radiation protection survey has been carried out at a high-energy neutron therapy facility using a combination of different detectors and counters. Included in the survey were measurements with a tissue equivalent proportional counter (TEPC), a rem meter, a large volume ionisation chamber (LVI) and a Geiger counter. Dose equivalent rates, normalised to a proton beam current of 25 μA, of between 1 μSv.h -1 and 0.7 Sv.h -1 were recorded depending on the location. In general the results confirm the tendency of the rem meter to over-read in fields consisting mainly of low energy neutrons and illustrate the advantages of the diagnostic and gamma discriminating properties of the TEPC. The LVI-Geiger system was found to be the least favourable combination of dosemeters, substantially under-reading and being unable to estimate the neutron dose rate at levels below about 32 μGy.h -1 . (author)

  4. Comparison Between In-Beam and Offline Positron Emission Tomography Imaging of Proton and Carbon Ion Therapeutic Irradiation at Synchrotron- and Cyclotron-Based Facilities

    International Nuclear Information System (INIS)

    Parodi, Katia; Bortfeld, Thomas; Haberer, Thomas

    2008-01-01

    Purpose: The benefit of using dedicated in-beam positron emission tomography (PET) detectors in the treatment room instead of commercial tomographs nearby is an open question. This work quantitatively compares the measurable signal for in-beam and offline PET imaging, taking into account realistic acquisition strategies at different ion beam facilities. Both scenarios of pulsed and continuous irradiation from synchrotron and cyclotron accelerators are considered, because of their widespread use in most carbon ion and proton therapy centers. Methods and Materials: A mathematical framework is introduced to compare the time-dependent amount and spatial distribution of decays from irradiation-induced isotope production. The latter is calculated with Monte Carlo techniques for real proton treatments of head-and-neck and paraspinal tumors. Extrapolation to carbon ion irradiation is based on results of previous phantom experiments. Biologic clearance is modeled taking into account available data from previous animal and clinical studies. Results: Ratios between the amount of physical decays available for in-beam and offline detection range from 40% to 60% for cyclotron-based facilities, to 65% to 110% (carbon ions) and 94% to 166% (protons) at synchrotron-based facilities, and increase when including biologic clearance. Spatial distributions of decays during irradiation exhibit better correlation with the dose delivery and reduced influence of biologic processes. Conclusions: In-beam imaging can be advantageous for synchrotron-based facilities, provided that efficient PET systems enabling detection of isotope decays during beam extraction are implemented. For very short (<2 min) irradiation times at cyclotron-based facilities, a few minutes of acquisition time after the end of irradiation are needed for counting statistics, thus affecting patient throughput

  5. Deuteron beam interaction with lithium jet in a neutron source test facility

    International Nuclear Information System (INIS)

    Hassanein, A.

    1996-01-01

    Testing and evaluating candidate fusion reactor materials in a high-flux, high-energy neutron environment are critical to the success and economic feasibility of a fusion device. The current understanding of materials behavior in fission-like environments and existing fusion facilities is insufficient to ensure the necessary performance of future fusion reactor components. An accelerator-based deuterium-lithium system to generate the required high neutron flux for material testing is considered to be the most promising approach in the near future. In this system, a high-energy (30-40 MeV) deuteron beam impinges on a high-speed (10-20 m/s) lithium jet to produce the high-energy (≥14 MeV) neutrons required to simulate a fusion environment via the Li (d,n) nuclear stripping reaction. Interaction of the high-energy deuteron beam and the subsequent response of the high-speed lithium jet are evaluated in detail. Deposition of the deuteron beam, jet-thermal hydraulic response, lithium-surface vaporization rate, and dynamic stability of the jet are modeled. It is found that lower beam kinetic energies produce higher surface temperature and consequently higher Li vaporization rates. Larger beam sizes significantly reduce both bulk and surface temperatures. Thermal expansion and dynamic velocities (normal to jet direction) due to beam energy deposition and momentum transfer are much lower than jet flow velocity and decrease substantially at lower beam current densities. (orig.)

  6. Deuteron beam interaction with Li jet for a neutron source test facility

    International Nuclear Information System (INIS)

    Hassanein, A.

    1995-09-01

    Testing and evaluating candidate fusion reactor materials in a high-flux, high-energy neutron environment are critical to the success and economic feasibility of a fusion device. The current understanding of materials behavior in fission-like environments and existing fusion facilities is insufficient to ensure the necessary performance of future fusion reactor components. An accelerator-based deuterium-lithium system to generate the required high neutron flux for material testing is considered to be the most promising approach in the near future. In this system, a high-energy (30-40 MeV) deuteron beam impinges on a high-speed (10-20 m/s) lithium jet to produce the high-energy (>14 MeV) neutrons required to simulate a fusion environment via the Li (d,n) nuclear stripping reaction. Interaction of the high-energy deuteron beam and the subsequent response of the high-speed lithium jet are evaluated in detail. Deposition of the deuteron beam, jet-thermal hydraulic response, lithium-surface vaporization rate, and dynamic stability of the jet are modeled. It is found that lower beam kinetic energies produce higher surface temperature and consequently higher Li vaporization rates. Larger beam sizes significantly reduce both bulk and surface temperatures. Thermal expansion and dynamic velocities (normal to jet direction) due to beam energy deposition and momentum transfer are much lower than jet flow velocity and decrease substantially at lower beam current densities

  7. An Indian test facility to characterise diagnostic neutral beam for ITER

    International Nuclear Information System (INIS)

    Singh, M.J.; Bandyopadhyay, M.; Rotti, C.; Singh, N.P.; Shah, Sejal; Bansal, G.; Gahlaut, A.; Soni, J.; Lakdawala, H.; Waghela, Harshad; Ahmed, I.; Roopesh, G.; Baruah, U.K.; Chakraborty, A.K.

    2011-01-01

    The diagnostic neutral beam (DNB) line shall be used to diagnose the He ash content in the D-T phase of the ITER machine using the charge exchange recombination spectroscopy (CXRS). Implementation of a successful DNB at ITER requires several challenges related to the production, neutralization and transport of the neutral beam over path lengths of 20.665 m, to be overcome. The delivery is aided if the above effects are tested prior to onsite commissioning. As DNB is a procurement package for INDIA, an ITER approved Indian test facility, INTF, is under construction at Institute for Plasma Research (IPR), India and is envisaged to be operational in 2015. The timeline for this facility is synchronized with the RADI, ELISE (IPP, Garching), SPIDER (RFX, Padova) in a manner that best utilization of configurational inputs available from them are incorporated in the design. This paper describes the facility in detail and discusses the experiments planned to optimise the beam transmission and testing of the beam line components using various diagnostics.

  8. Detailed design of the RF source for the 1 MV neutral beam test facility

    International Nuclear Information System (INIS)

    Marcuzzi, D.; Palma, M. Dalla; Pavei, M.; Heinemann, B.; Kraus, W.; Riedl, R.

    2009-01-01

    In the framework of the EU activities for the development of the Neutral Beam Injector for ITER, the detailed design of the Radio Frequency (RF) driven negative ion source to be installed in the 1 MV ITER Neutral Beam Test Facility (NBTF) has been carried out. Results coming from ongoing R and D on IPP test beds [A. Staebler et al., Development of a RF-Driven Ion Source for the ITER NBI System, this conference] and the design of the new ELISE facility [B. Heinemann et al., Design of the Half-Size ITER Neutral Beam Source Test Facility ELISE, this conference] brought several modifications to the solution based on the previous design. An assessment was carried out regarding the Back-Streaming positive Ions (BSI+) that impinge on the back plates of the ion source and cause high and localized heat loads. This led to the redesign of most heated components to increase cooling, and to different choices for the plasma facing materials to reduce the effects of sputtering. The design of the electric circuit, gas supply and the other auxiliary systems has been optimized. Integration with other components of the beam source has been revised, with regards to the interfaces with the supporting structure, the plasma grid and the flexible connections. In the paper the design will be presented in detail, as well as the results of the analyses performed for the thermo-mechanical verification of the components.

  9. The Proton Beams for the New Time-of-Flight Neutron Facility at the CERN-PS

    CERN Document Server

    Cappi, R; Métral, G

    2000-01-01

    The experimental determination of neutron cross sections in fission and capture reactions as a function of the neutron energy is of primary importance in nuclear physics. Recent developments at CERN and elsewhere have shown that many fields of research and development, such as the design of Accelerator-Driven Systems (ADS) for nuclear waste incineration, nuclear astrophysics, fundamental nuclear physics, dosimetry for radiological protection and therapy, would benefit from a better knowledge of neutron cross sections. A neutron facility at the CERN-PS has been proposed with the aim of carrying out a systematic and high resolution study of neutron cross sections through Time-Of-Flight (n-TOF) measurement. The facility requires a high intensity proton beam (about 0.7x1013 particles/bunch) distributed in a short bunch (about 25 ns total length) to produce the neutrons by means of a spallation process in a lead target. To achieve these characteristics, a number of complex beam gymnastics have to be performed. All...

  10. NA61/SHINE facility at the CERN SPS: beams and detector system

    CERN Document Server

    Abgrall, N.; Aduszkiewicz, A.; Ali, Y.; Anticic, T.; Antoniou, N.; Baatar, B.; Bay, F.; Blondel, A.; Blumer, J.; Bogomilov, M.; Bogusz, M.; Bravar, A.; Brzychczyk, J.; Bunyatov, S.A.; Christakoglou, P.; Czopowicz, T.; Davis, N.; Debieux, S.; Dembinski, H.; Diakonos, F.; Di Luise, S.; Dominik, W.; Drozhzhova, T.; Dumarchez, J.; Dynowski, K.; Engel, R.; Efthymiopoulos, I.; Ereditato, A.; Fabich, A.; Feofilov, G.A.; Fodor, Z.; Fulop, A.; Gazdzicki, M.; Golubeva, M.; Grebieszkow, K.; Grzeszczuk, A.; Guber, F.; Haesler, A.; Hasegawa, T.; Hierholzer, M.; Idczak, R.; Igolkin, S.; Ivashkin, A.; Jokovic, D.; Kadija, K.; Kapoyannis, A.; Kaptur, E.; Kielczewska, D.; Kirejczyk, M.; Kisiel, J.; Kiss, T.; Kleinfelder, S.; Kobayashi, T.; Kolesnikov, V.I.; Kolev, D.; Kondratiev, V.P.; Korzenev, A.; Koversarski, P.; Kowalski, S.; Krasnoperov, A.; Kurepin, A.; Larsen, D.; Laszlo, A.; Lyubushkin, V.V.; Maćkowiak-Pawlowska, M.; Majka, Z.; Maksiak, B.; Malakhov, A.I.; Maletic, D.; Manglunki, D.; Manic, D.; Marchionni, A.; Marcinek, A.; Marin, V.; Marton, K.; Mathes, H.J; Matulewicz, T.; Matveev, V.; Melkumov, G.L.; Messina, M.; Mrówczyński, St.; Murphy, S.; Nakadaira, T.; Nirkko, M.; Nishikawa, K.; Palczewski, T.; Palla, G.; Panagiotou, A.D.; Paul, T.; Peryt, W.; Petukhov, O.; Pistillo, C.; Planeta, R.; Pluta, J.; Popov, B.A.; Posiadala, M.; Puławski, S.; Puzovic, J.; Rauch, W.; Ravonel, M.; Redij, A.; Renfordt, R.; Richter-Was, E.; Robert, A.; Röhrich, D.; Rondio, E.; Rossi, B.; Roth, M.; Rubbia, A.; Rustamov, A.; Rybczyński, M.; Sadovsky, A.; Sakashita, K.; Savic, M.; Schmidt, K.; Sekiguchi, T.; Seyboth, P.; Sgalaberna, D.; Shibata, M.; Sipos, R.; Skrzypczak, E.; Słodkowski, M.; Sosin, Z.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Stroebele, H.; Susa, T.; Szuba, M.; Tada, M.; Tereshchenko, V.; Tolyhi, T.; Tsenov, R.; Turko, L.; Ulrich, R.; Unger, M.; Vassiliou, M.; Veberic, D.; Vechernin, V.V.; Vesztergombi, G.; Vinogradov, L.; Wilczek, A.; Włodarczyk, Z.; Wojtaszek-Szwarz, A.; Wyszyński, O.; Zambelli, L.; Zipper, W.

    2014-01-01

    NA61/SHINE (SPS Heavy Ion and Neutrino Experiment) is a multi-purpose experimental facility to study hadron production in hadron-proton, hadron-nucleus and nucleus-nucleus collisions at the CERN Super Proton Synchrotron. It recorded the first physics data with hadron beams in 2009 and with ion beams (secondary 7Be beams) in 2011. NA61/SHINE has greatly profited from the long development of the CERN proton and ion sources and the accelerator chain as well as the H2 beamline of the CERN North Area. The latter has recently been modified to also serve as a fragment separator as needed to produce the Be beams for NA61/SHINE. Numerous components of the NA61/SHINE set-up were inherited from its predecessors, in particular, the last one, the NA49 experiment. Important new detectors and upgrades of the legacy equipment were introduced by the NA61/SHINE Collaboration. This paper describes the state of the NA61/SHINE facility - the beams and the detector system - before the CERN Long Shutdown I, which started in March ...

  11. Transcript of the workshop to discuss plans for a National High Intensity Radioactive Nuclear Beam Facility

    International Nuclear Information System (INIS)

    Nitschke, J.M.

    1989-01-01

    Following the ''First International Conference on Radioactive Nuclear Beams'' in Berkeley, a workshop was held on October 19, 1989 at the Lawrence Berkeley Laboratory to discuss plans for a National High Intensity Radioactive Nuclear Beam (RNB) Facility. The purpose of the workshop was -- after having discussed during the conference the physics question that can be addressed with RNBs -- to evaluate more concretely the possibilities for actually constructing such a facility in this country. It is becoming increasingly apparent that facility producing beams of radioactive nuclei with extreme neutron-to-proton ratios is of high scientific interest and technically feasible. It would allow the study of nuclear structure and astrophysical reactions very far from the line of stable nuclei, and could provide new possibilities of reaching the long-sought island of stability of superheavy nuclei. Such facilities are under advanced consideration in Japan and at CERN in Europe. This paper contains a slightly edited transcript of the tape recording that was made of the workshop

  12. Impact of Spot Size and Beam-Shaping Devices on the Treatment Plan Quality for Pencil Beam Scanning Proton Therapy

    International Nuclear Information System (INIS)

    Moteabbed, Maryam; Yock, Torunn I.; Depauw, Nicolas; Madden, Thomas M.; Kooy, Hanne M.; Paganetti, Harald

    2016-01-01

    Purpose: This study aimed to assess the clinical impact of spot size and the addition of apertures and range compensators on the treatment quality of pencil beam scanning (PBS) proton therapy and to define when PBS could improve on passive scattering proton therapy (PSPT). Methods and Materials: The patient cohort included 14 pediatric patients treated with PSPT. Six PBS plans were created and optimized for each patient using 3 spot sizes (∼12-, 5.4-, and 2.5-mm median sigma at isocenter for 90- to 230-MeV range) and adding apertures and compensators to plans with the 2 larger spots. Conformity and homogeneity indices, dose-volume histogram parameters, equivalent uniform dose (EUD), normal tissue complication probability (NTCP), and integral dose were quantified and compared with the respective PSPT plans. Results: The results clearly indicated that PBS with the largest spots does not necessarily offer a dosimetric or clinical advantage over PSPT. With comparable target coverage, the mean dose (D_m_e_a_n) to healthy organs was on average 6.3% larger than PSPT when using this spot size. However, adding apertures to plans with large spots improved the treatment quality by decreasing the average D_m_e_a_n and EUD by up to 8.6% and 3.2% of the prescribed dose, respectively. Decreasing the spot size further improved all plans, lowering the average D_m_e_a_n and EUD by up to 11.6% and 10.9% compared with PSPT, respectively, and eliminated the need for beam-shaping devices. The NTCP decreased with spot size and addition of apertures, with maximum reduction of 5.4% relative to PSPT. Conclusions: The added benefit of using PBS strongly depends on the delivery configurations. Facilities limited to large spot sizes (>∼8 mm median sigma at isocenter) are recommended to use apertures to reduce treatment-related toxicities, at least for complex and/or small tumors.

  13. LHCB: A LHCb-VELO module as beam quality monitor for proton therapy beam at the Clatterbridge Centre for Oncology

    CERN Multimedia

    Casse, G; Patel, G D; Smith, N A; Kacperek, A; Marsland, B

    2010-01-01

    The progress in detector technology, driven by the needs of particle tracking and vertexing in the present LHC and its upgrade (sLHC), has led to the design of silicon sensors with low mass, high granularity, high speed and unprecedented radiation hardness. The sensors designed for such a harsh environment can be profitably used for instrumenting the control systems of therapeutic hadron beams. The high granularity and readout clock speed are well suited for monitoring continuous beam currents. The low mass allows reduced interference with the beam whilst monitoring its profile with high precision. The high resolution and sensitivity to minimum ionising particles allows monitoring of the beam spot position by measurement of the halo in real time, without any interference with the beam spot used in therapy.

  14. Early experience of proton beam therapy combined with chemotherapy for locally advanced oropharyngeal cancer

    International Nuclear Information System (INIS)

    Ishikawa, Youjirou; Nakamura, Tatsuya; Takada, Akinori; Takayama, Kanako; Makita, Chiyoko; Suzuki, Motohisa; Azami, Yusuke; Kikuchi, Yasuhiro; Fuwa, Nobukazu

    2013-01-01

    Between 2009 and 2012, 10 patients with advanced oropharyngeal cancer underwent proton therapy combined with chemotherapy. The initial results of this therapy were 8 complete response (CR) and 2 partial response (PR), local recurrence was detected 1 patient. Proton beam therapy combined with chemotherapy is thought to be an effective treatment for locally advanced oropharyngeal cancer. (author)

  15. 3D printed plastics for beam modulation in proton therapy

    International Nuclear Information System (INIS)

    Lindsay, C; Hoehr, C; Kumlin, J; Schaffer, P; Jirasek, A; Lee, R; Martinez, D M

    2015-01-01

    Two 3D printing methods, fused filament fabrication (FFF) and PolyJet™ (PJ) were investigated for suitability in clinical proton therapy (PT) energy modulation. Measurements of printing precision, printed density and mean stopping power are presented. FFF is found to be accurate to 0.1 mm, to contain a void fraction of 13% due to air pockets and to have a mean stopping power dependent on geometry. PJ was found to print accurate to 0.05 mm, with a material density and mean stopping power consistent with solid poly(methyl methacrylate) (PMMA). Both FFF and PJ were found to print significant, sporadic defects associated with sharp edges on the order of 0.2 mm. Site standard PT modulator wheels were printed using both methods. Measured depth-dose profiles with a 74 MeV beam show poor agreement between PMMA and printed FFF wheels. PJ printed wheel depth-dose agreed with PMMA within 1% of treatment dose except for a distal falloff discrepancy of 0.5 mm. (note)

  16. Proton Beam Therapy Interference With Implanted Cardiac Pacemakers

    International Nuclear Information System (INIS)

    Oshiro, Yoshiko; Sugahara, Shinji; Noma, Mio; Sato, Masato; Sakakibara, Yuzuru; Sakae, Takeji; Hayashi, Yasutaka; Nakayama, Hidetsugu; Tsuboi, Koji; Fukumitsu, Nobuyoshi; Kanemoto, Ayae; Hashimoto, Takayuki; Tokuuye, Koichi

    2008-01-01

    Purpose: To investigate the effect of proton beam therapy (PBT) on implanted cardiac pacemaker function. Methods and Materials: After a phantom study confirmed the safety of PBT in patients with cardiac pacemakers, we treated 8 patients with implanted pacemakers using PBT to a total tumor dose of 33-77 gray equivalents (GyE) in dose fractions of 2.2-6.6 GyE. The combined total number of PBT sessions was 127. Although all pulse generators remained outside the treatment field, 4 patients had pacing leads in the radiation field. All patients were monitored by means of electrocardiogram during treatment, and pacemakers were routinely examined before and after PBT. Results: The phantom study showed no effect of neutron scatter on pacemaker generators. In the study, changes in heart rate occurred three times (2.4%) in 2 patients. However, these patients remained completely asymptomatic throughout the PBT course. Conclusions: PBT can result in pacemaker malfunctions that manifest as changes in pulse rate and pulse patterns. Therefore, patients with cardiac pacemakers should be monitored by means of electrocardiogram during PBT

  17. Test facility for the development of 150-keV, multi-megawatt neutral beam systems

    International Nuclear Information System (INIS)

    Haughian, W.; Baker, W.R.; Biagi, L.A.; Hopkins, D.B.

    1975-11-01

    The next generation of CTR experiments, such as the Tokamak Fusion Test Reactor (TFTR), will require neutral-beam injection systems that produce multi-megawatt, 120-keV deuterium-beam pulses of 0.5-second duration. Since present injection systems are operating in the 10- to 40-keV range, an intensive development effort is in progress to meet a 150-keV requirement. The vacuum system and power supplies that make up a test facility to be used in the development of these injectors are described

  18. The CERN n_TOF Facility: Neutron Beams Performances for Cross Section Measurements

    CERN Document Server

    Chiaveri, E; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Bečvář, F; Belloni, F; Berthoumieux, E; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviani, M; Calviño, F; Cano-Ott, D; Carrapiço, C; Cerutti, F; Chin, M; Colonna, N; Cortés, G; Cortés-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Guerrero, C; Gunsing, F; Gurusamy, P; Hernández-Prieto, A; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Kivel, N; Koehler, P; Kokkoris, M; Krtička, M; Kroll, J; Lampoudis, C; Langer, C; Leal-Cidoncha, E; Lederer, C; Leeb, H; Leong, L S; Losito, R; Mallick, A; Manousos, A; Marganiec, J; Martínez, T; Massimi, C; Mastinu, P F; Mastromarco, M; Meaze, M; Mendoza, E; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondalaers, W; Paradela, C; Pavlik, A; Perkowski, J; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Robles, M S; Roman, F; Rubbia, C; Sabaté-Gilarte, M; Sarmento, R; Saxena, A; Schillebeeckx, P; Schmidt, S; Schumann, D; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Tsinganis, A; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Vlachoudis, V; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiss, C; Wright, T; Žugec, P

    2014-01-01

    This paper presents the characteristics of the existing CERN n\\_TOF neutron beam facility (n\\_TOF-EAR1 with a flight path of 185 meters) and the future one (n\\_TOF EAR-2 with a flight path of 19 meters), which will operate in parallel from Summer 2014. The new neutron beam will provide a 25 times higher neutron flux delivered in 10 times shorter neutron pulses, thus offering more powerful capabilities for measuring small mass, low cross section and/or high activity samples.

  19. A facility for liquid-phase radiation experiments on heavy ion beams

    International Nuclear Information System (INIS)

    Stuglik, Z.; Zvara, I.; Yakushev, A.B.; Timokhin, S.N.

    1992-01-01

    The title facility is described, installed on a beam line of the 4-meter U-400 cyclotron in the Flerov Laboratory of Nuclear Reactions, JINR, Dubna. The accelerator provides intermediate energy (some 10 MeV/nucleon) beams of ions from Li to Xe. Preliminary results on the radiolysis of two liquid systems -Fricke solution and malachite green in ethanol - by 11 B, 24 Mg, and 40 Ca ions are presented. Some experimental problems and uncertainities faced at the quantitative evaluation of the data are discussed. 62 refs.; 5 figs.; 2 tabs

  20. A facility for liquid-phase radiation experiments on heavy ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Stuglik, Z; Zvara, I; Yakushev, A B; Timokhin, S N

    1993-12-31

    The title facility is described, installed on a beam line of the 4-meter U-400 cyclotron in the Flerov Laboratory of Nuclear Reactions, JINR, Dubna. The accelerator provides intermediate energy (some 10 MeV/nucleon) beams of ions from Li to Xe. Preliminary results on the radiolysis of two liquid systems -Fricke solution and malachite green in ethanol - by {sup 11}B, {sup 24}Mg, and {sup 40}Ca ions are presented. Some experimental problems and uncertainities faced at the quantitative evaluation of the data are discussed. 62 refs.; 5 figs.; 2 tabs.

  1. Laser beam smoothing and backscatter saturation processes in plasmas relevant to national ignition facility hohlraums

    International Nuclear Information System (INIS)

    MacGowan, B.J.; Berger, R.L.; Cohen, B.I.

    2001-01-01

    We have used gas-filled targets irradiated by the Nova laser to simulate National Ignition Facility (NIF) hohlraum plasmas and to study the dependence of Stimulated Raman (SRS) and Brillouin (SBS) Scattering on beam smoothing at a range of laser intensities (3ω, 2-410 15 Wcm -2 ) and plasma conditions. We have demonstrated the effectiveness of polarization smoothing as a potential upgrade to the NIF. Experiments with higher intensities and higher densities characteristic of 350eV hohlraum designs indicate that with appropriate beam smoothing the backscatter from such hohlraums may be tolerable. (author)

  2. Rhabdomyosarcoma of the trachea: first reported case treated with proton beam therapy.

    Science.gov (United States)

    Exley, R; Bernstein, J M; Brennan, B; Rothera, M P

    2012-09-01

    We report a case of rhabdomyosarcoma of the trachea in a 14-month-old child, and we present the first reported use of proton beam therapy for this tumour. A 14-month-old girl presented acutely with a seven-day history of biphasic stridor. Emergency endoscopic debulking of a posterior tracheal mass was undertaken. Histological examination revealed an embryonal rhabdomyosarcoma with anaplasia. Multimodality therapy with surgery and chemotherapy was administered in the UK, and proton beam therapy in the USA. Only three cases of rhabdomyosarcoma of the trachea have previously been reported in the world literature. This is the first reported case of treatment of this tumour with proton beam therapy. Compared with conventional radiotherapy, proton beam therapy may confer improved long-term outcome in children, with benefits including reduced irradiation of the spinal cord.

  3. Future carbon beams at SPIRAL1 facility: Which method is the most efficient?

    Science.gov (United States)

    Maunoury, L.; Delahaye, P.; Angot, J.; Dubois, M.; Dupuis, M.; Frigot, R.; Grinyer, J.; Jardin, P.; Leboucher, C.; Lamy, T.

    2014-02-01

    Compared to in-flight facilities, Isotope Separator On-Line ones can in principle produce significantly higher radioactive ion beam intensities. On the other hand, they have to cope with delays for the release and ionization which make the production of short-lived isotopes ion beams of reactive and refractory elements particularly difficult. Many efforts are focused on extending the capabilities of ISOL facilities to those challenging beams. In this context, the development of carbon beams is triggering interest [H. Frånberg, M. Ammann, H. W. Gäggeler, and U. Köster, Rev. Sci. Instrum. 77, 03A708 (2006); M. Kronberger, A. Gottberg, T. M. Mendonca, J. P. Ramos, C. Seiffert, P. Suominen, and T. Stora, in Proceedings of the EMIS 2012 [Nucl. Instrum. Methods Phys. Res. B Production of molecular sideband radioisotope beams at CERN-ISOLDE using a Helicon-type plasma ion source (to be published)]: despite its refractory nature, radioactive carbon beams can be produced from molecules (CO or CO2), which can subsequently be broken up and multi-ionized to the required charge state in charge breeders or ECR sources. This contribution will present results of experiments conducted at LPSC with the Phoenix charge breeder and at GANIL with the Nanogan ECR ion source for the ionization of carbon beams in the frame of the ENSAR and EMILIE projects. Carbon is to date the lightest condensable element charge bred with an ECR ion source. Charge breeding efficiencies will be compared with those obtained using Nanogan ECRIS and charge breeding times will be presented as well.

  4. Development of a Tandem-ElectroStatic-Quadrupole accelerator facility for Boron Neutron Capture Therapy (BNCT)

    International Nuclear Information System (INIS)

    Kreiner, A.J.; Thatar Vento, V.; Levinas, P.; Bergueiro, J.; Burlon, A.A.; Di Paolo, H.; Kesque, J.M.; Valda, A.A.; Debray, M.E.; Somacal, H.R.; Minsky, D.M.; Estrada, L.; Hazarabedian, A.; Johann, F.; Suarez Sandin, J.C.; Castell, W.; Davidson, J.; Davidson, M.; Repetto, M.; Obligado, M.; Nery, J.P.; Huck, H.; Igarzabal, M.; Fernandez Salares, A.

    2008-01-01

    There is a generalized perception that the availability of suitable particle accelerators installed in hospitals, as neutron sources, may be crucial for the advancement of Boron Neutron Capture Therapy (BNCT). An ongoing project to develop a Tandem-ElectroStatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based (AB)-BNCT is described here. The project goal is a machine capable of delivering 30 mA of 2.4-2.5 MeV protons to be used in conjunction with a neutron production target based on the 7 Li(p,n) 7 Be reaction slightly beyond its resonance at 2.25 MeV. A folded tandem, with 1.20-1.25 MV terminal voltage, combined with an ESQ chain is being designed and constructed. This machine is conceptually shown to be capable of accelerating a 30 mA proton beam to 2.5 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the 7 Li(p,n) 7 Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. This electrostatic machine is one of the technologically simplest and cheapest solutions for optimized AB-BNCT. At present there is no BNCT facility in the world with the characteristics presented in this work. For the accelerator, results on its design, construction and beam transport calculations are discussed. Taking into account the peculiarities of the expected irradiation field, the project also considers a specific study of the treatment room. This study aims at the design of the treatment room emphasizing aspects related to patient, personnel and public radiation protection; dose monitoring; patient positioning and room construction. The design considers both thermal (for the treatment of shallow tumors) and epithermal (for deep-seated tumors) neutron beams entering the room through a port connected to the accelerator via a moderation and neutron beam shaping assembly. Preliminary results of dose calculations for the treatment room design, using the MCNP program, are presented

  5. Beam-Beam Effects

    International Nuclear Information System (INIS)

    Herr, W; Pieloni, T

    2014-01-01

    One of the most severe limitations in high-intensity particle colliders is the beam-beam interaction, i.e. the perturbation of the beams as they cross the opposing beams. This introduction to beam-beam effects concentrates on a description of the phenomena that are present in modern colliding beam facilities

  6. Design Optimisation of a High Intensity Beam Facility and Feasibility Experiment of a Solid Fragmented Target

    CERN Document Server

    Charitonidis, Nikolaos; Rivkin, Leonid

    2014-06-13

    The present PhD thesis describes the design, execution and results of the HRMT-10 experiment performed at the HiRadMat facility of the CERN/SPS complex. The first part of the thesis covers the design optimization studies of the HiRadMat facility, focusing in particular on the radiation protection issues. A detailed Monte-Carlo model of the facility has been developed and validated through comparison with measurements. A very satisfactory agreement between the simulation and the experimental data is observed. In the second part of this thesis, a novel feasibility experiment of a fragmented solid target for a future Neutrino Factory or a Super Beam facility, able to support high beam powers ( 1 MW) is presented in detail. A solid granular target has been proposed as an interesting alternative to an open Hg jet target, presently considered as the baseline for such facilities, but posing considerable technical challenges. The HRMT-10 experiment seeks to address the lack of experimental data of the feasibility of...

  7. Thermal shock tests with beryllium coupons in the electron beam facility JUDITH

    International Nuclear Information System (INIS)

    Roedig, M.; Duwe, R.; Schuster, J.L.A.

    1995-01-01

    Several grades of American and Russian beryllium have been tested in high heat flux tests by means of an electron beam facility. For safety reasons, major modifications of the facility had to be fulfilled in advance to the tests. The influence of energy densities has been investigated in the range between 1 and 7 MJ/m 2 . In addition the influence of an increasing number of shots at constant energy density has been studied. For all samples, surface profiles have been measured before and after the experiments. Additional information has been gained from scanning electron microscopy, and from metallography

  8. Economic and education impact of building the Continuous Electron Beam Accelerator Facility

    International Nuclear Information System (INIS)

    Hartline, B.

    1996-01-01

    The Continuous Electron Beam Accelerator Facility (CEBAF) was built in Newport News, Virginia, between 1987 and 1995 and is a new basic research laboratory christened the Thomas Jefferson National Accelerator Facility (Jefferson Lab). Jefferson Lab's science and technology mission has major economic and educational benefits: basic research discoveries, improvement and application of key technologies associated with the accelerator and the experiments, extensive subcontracting with industry, and diverse employment and educational opportunities. The $600 million invested by federal, state, local and international partners to build Jefferson Lab has had substantial economic and educational benefits locally, as well as significant benefits distributed among industries and universities throughout the United States

  9. Design and use of an MITR-II beam port facility for undergraduate education

    International Nuclear Information System (INIS)

    Kwok, K.S.; Fecych, W.; Shull, C.G.; Bernard, J.A.

    1985-01-01

    This summary describes the design and use of a one-axis flight-time neutron spectrometer that has been installed on one of the beam ports of the 5-MW(t) Massachusetts Institute of Technology Research Reactor (MITR). The objective of this facility is to further undergraduate education by making a quality experimental facility available for student use. This spectrometer, which has now been in use for two years, has received excellent evaluations from the more than 100 undergraduates who have made measurements with it

  10. Proton Beam Therapy and Concurrent Chemotherapy for Esophageal Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Steven H., E-mail: shlin@mdanderson.org [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Komaki, Ritsuko; Liao Zhongxing [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Wei, Caimiao [Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Myles, Bevan [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Guo Xiaomao [Department of Radiation Oncology, Fudan University Cancer Hospital, Shanghai (China); Palmer, Matthew [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe [Department of Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Swisher, Stephen G.; Hofstetter, Wayne L. [Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Ajani, Jaffer A. [Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Cox, James D. [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2012-07-01

    Purpose: Proton beam therapy (PBT) is a promising modality for the management of thoracic malignancies. We report our preliminary experience of treating esophageal cancer patients with concurrent chemotherapy (CChT) and PBT (CChT/PBT) at MD Anderson Cancer Center. Methods and Materials: This is an analysis of 62 esophageal cancer patients enrolled on a prospective study evaluating normal tissue toxicity from CChT/PBT from 2006 to 2010. Patients were treated with passive scattering PBT with two- or three-field beam arrangement using 180 to 250 MV protons. We used the Kaplan-Meier method to assess time-to-event outcomes and compared the distributions between groups using the log-rank test. Results: The median follow-up time was 20.1 months for survivors. The median age was 68 years (range, 38-86). Most patients were males (82%) who had adenocarcinomas (76%) and Stage II-III disease (84%). The median radiation dose was 50.4 Gy (RBE [relative biologic equivalence]) (range, 36-57.6). The most common grade 2 to 3 acute toxicities from CChT/PBT were esophagitis (46.8%), fatigue (43.6%), nausea (33.9%), anorexia (30.1%), and radiation dermatitis (16.1%). There were two cases of grade 2 and 3 radiation pneumonitis and two cases of grade 5 toxicities. A total of 29 patients (46.8%) received preoperative CChT/PBT, with one postoperative death. The pathologic complete response (pCR) rate for the surgical cohort was 28%, and the pCR and near CR rates (0%-1% residual cells) were 50%. While there were significantly fewer local-regional recurrences in the preoperative group (3/29) than in the definitive CChT/PBT group (16/33) (log-rank test, p = 0.005), there were no differences in distant metastatic (DM)-free interval or overall survival (OS) between the two groups. Conclusions: This is the first report of patients treated with PBT/CChT for esophageal cancer. Our data suggest that this modality is associated with a few severe toxicities, but the pathologic response and clinical

  11. Proton Beam Therapy and Concurrent Chemotherapy for Esophageal Cancer

    International Nuclear Information System (INIS)

    Lin, Steven H.; Komaki, Ritsuko; Liao Zhongxing; Wei, Caimiao; Myles, Bevan; Guo Xiaomao; Palmer, Matthew; Mohan, Radhe; Swisher, Stephen G.; Hofstetter, Wayne L.; Ajani, Jaffer A.; Cox, James D.

    2012-01-01

    Purpose: Proton beam therapy (PBT) is a promising modality for the management of thoracic malignancies. We report our preliminary experience of treating esophageal cancer patients with concurrent chemotherapy (CChT) and PBT (CChT/PBT) at MD Anderson Cancer Center. Methods and Materials: This is an analysis of 62 esophageal cancer patients enrolled on a prospective study evaluating normal tissue toxicity from CChT/PBT from 2006 to 2010. Patients were treated with passive scattering PBT with two- or three-field beam arrangement using 180 to 250 MV protons. We used the Kaplan-Meier method to assess time-to-event outcomes and compared the distributions between groups using the log–rank test. Results: The median follow-up time was 20.1 months for survivors. The median age was 68 years (range, 38–86). Most patients were males (82%) who had adenocarcinomas (76%) and Stage II-III disease (84%). The median radiation dose was 50.4 Gy (RBE [relative biologic equivalence]) (range, 36–57.6). The most common grade 2 to 3 acute toxicities from CChT/PBT were esophagitis (46.8%), fatigue (43.6%), nausea (33.9%), anorexia (30.1%), and radiation dermatitis (16.1%). There were two cases of grade 2 and 3 radiation pneumonitis and two cases of grade 5 toxicities. A total of 29 patients (46.8%) received preoperative CChT/PBT, with one postoperative death. The pathologic complete response (pCR) rate for the surgical cohort was 28%, and the pCR and near CR rates (0%–1% residual cells) were 50%. While there were significantly fewer local-regional recurrences in the preoperative group (3/29) than in the definitive CChT/PBT group (16/33) (log–rank test, p = 0.005), there were no differences in distant metastatic (DM)-free interval or overall survival (OS) between the two groups. Conclusions: This is the first report of patients treated with PBT/CChT for esophageal cancer. Our data suggest that this modality is associated with a few severe toxicities, but the pathologic response and

  12. ISABELLE: a 400 x 400 GeV proton--proton colliding beam facility

    International Nuclear Information System (INIS)

    1978-01-01

    A conceptual design report is presented for the construction of an Intersecting Storage Accelerator, ISABELLE, to be located at Brookhaven National Laboratory. At this major research facility beams of protons with energies up to 400 GeV will be collided in six experimental areas. At each area particle physicists will install detector apparatus to study the interaction and reaction products for such very high energy collisions. The proposal results from several years of study and development work on such a facility. Topics discussed include: (1) introduction and summary of the proposal; (2) physics at ISABELLE (including physics objectives and typical experiments and detectors); description of ISABELLE (overview; magnetic ring structure and lattice characteristics; performance; beam transfer, stacking, and acceleration; magnet system; refrigeration system; vacuum system; power supplies, instrumentation, and control system; physical plant and experimental halls; and operation and safety); and (3) cost estimate and schedule

  13. ISABELLE: a 400 x 400 GeV proton--proton colliding beam facility

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-01

    A conceptual design report is presented for the construction of an Intersecting Storage Accelerator, ISABELLE, to be located at Brookhaven National Laboratory. At this major research facility beams of protons with energies up to 400 GeV will be collided in six experimental areas. At each area particle physicists will install detector apparatus to study the interaction and reaction products for such very high energy collisions. The proposal results from several years of study and development work on such a facility. Topics discussed include: (1) introduction and summary of the proposal; (2) physics at ISABELLE (including physics objectives and typical experiments and detectors); description of ISABELLE (overview; magnetic ring structure and lattice characteristics; performance; beam transfer, stacking, and acceleration; magnet system; refrigeration system; vacuum system; power supplies, instrumentation, and control system; physical plant and experimental halls; and operation and safety); and (3) cost estimate and schedule.

  14. Prospects for studies of ground-state proton decays with the Holifield Radioactive Ion Beam Facility

    International Nuclear Information System (INIS)

    Toth, K.S.

    1994-01-01

    By using radioactive ions from the Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory it should be possible to identify many new ground-state proton emitters in the mass region from Sn to Pb. During this production and search process the limits of stability on the proton-rich side of the nuclidic chart will be delineated for a significant fraction of medium-weight elements and our understanding of the proton-emission process will be expanded and improved

  15. IOTA (Integrable Optics Test Accelerator): facility and experimental beam physics program

    Science.gov (United States)

    Antipov, S.; Broemmelsiek, D.; Bruhwiler, D.; Edstrom, D.; Harms, E.; Lebedev, V.; Leibfritz, J.; Nagaitsev, S.; Park, C. S.; Piekarz, H.; Piot, P.; Prebys, E.; Romanov, A.; Ruan, J.; Sen, T.; Stancari, G.; Thangaraj, C.; Thurman-Keup, R.; Valishev, A.; Shiltsev, V.

    2017-03-01

    The Integrable Optics Test Accelerator (IOTA) is a storage ring for advanced beam physics research currently being built and commissioned at Fermilab. It will operate with protons and electrons using injectors with momenta of 70 and 150 MeV/c, respectively. The research program includes the study of nonlinear focusing integrable optical beam lattices based on special magnets and electron lenses, beam dynamics of space-charge effects and their compensation, optical stochastic cooling, and several other experiments. In this article, we present the design and main parameters of the facility, outline progress to date and provide the timeline of the construction, commissioning and research. The physical principles, design, and hardware implementation plans for the major IOTA experiments are also discussed.

  16. IOTA (Integrable Optics Test Accelerator): Facility and experimental beam physics program

    International Nuclear Information System (INIS)

    Antipov, Sergei; Broemmelsiek, Daniel; Bruhwiler, David; Edstrom, Dean; Harms, Elvin

    2017-01-01

    The Integrable Optics Test Accelerator (IOTA) is a storage ring for advanced beam physics research currently being built and commissioned at Fermilab. It will operate with protons and electrons using injectors with momenta of 70 and 150 MeV/c, respectively. The research program includes the study of nonlinear focusing integrable optical beam lattices based on special magnets and electron lenses, beam dynamics of space-charge effects and their compensation, optical stochastic cooling, and several other experiments. In this article, we present the design and main parameters of the facility, outline progress to date and provide the timeline of the construction, commissioning and research. Finally, the physical principles, design, and hardware implementation plans for the major IOTA experiments are also discussed.

  17. Cavity beam position monitor system for the Accelerator Test Facility 2

    Directory of Open Access Journals (Sweden)

    Y. I. Kim

    2012-04-01

    Full Text Available The Accelerator Test Facility 2 (ATF2 is a scaled demonstrator system for final focus beam lines of linear high energy colliders. This paper describes the high resolution cavity beam position monitor (BPM system, which is a part of the ATF2 diagnostics. Two types of cavity BPMs are used, C-band operating at 6.423 GHz, and S-band at 2.888 GHz with an increased beam aperture. The cavities, electronics, and digital processing are described. The resolution of the C-band system with attenuators was determined to be approximately 250 nm and 1  μm for the S-band system. Without attenuation the best recorded C-band cavity resolution was 27 nm.

  18. 2 MeV, 60 kW dual-beam type electron accelerator irradiation facility

    International Nuclear Information System (INIS)

    Yotsumoto, Keiichi; Kanazawa, Takao; Haruyama, Yasuyuki; Agematsu, Takashi; Mizuhashi, Kiyoshi; Sunaga, Hiromi; Washino, Masamitsu; Tamura, Naoyuki

    1984-02-01

    The specification of new irradiation facility which has been constructed from 1978 through 1981 as the replacement of 1st Accelerator of JAERI, TRCRE are described. The accelerator is the Cockcroft-Walton type and both vertical and horizontal accelerating tubes are arranged on a single high voltage generator. Transferring of the high voltage to the horizontal accelerating tube is performed with the high voltage changing system in the pressure vessel. The output ratings of the accelerator are 2 MV of acceleration voltage and 30 mA of beam current. By providing the dual beam system, two irradiation rooms, one for vertical and the other for horizontal beam, are independently operationable. Persons can enter the horizontal irradiation room for experimental setting even when the vertical irradiation room is in operation. The specification of the buildings, the exhaust air treatment system, the irradiation conveyor and the safety observation system are also described. (author)

  19. Beam studies and experimental facility for the AWAKE experiment at CERN

    CERN Document Server

    Bracco, Chiara; Petrenko, Alexey; Timko, Helga; Argyropoulos, Theodoros; Bartosik, Hannes; Bohl, Thomas; Esteban Müller, Juan; Goddard, Brennan; Meddahi, Malika; Pardons, Ans; Shaposhnikova, Elena; Velotti, Francesco M; Vincke, Helmut

    2014-01-01

    A Proton Driven Plasma Wakefield Acceleration Experiment has been proposed as an approach to eventually accelerate an electron beam to the TeV energy range in a single plasma section. To verify this novel technique, a proof of principle R&D experiment, AWAKE, is planned at CERN using 400 GeV proton bunches from the SPS. An electron beam will be injected into the plasma cell to probe the accelerating wakefield. The AWAKE experiment will be installed in the CNGS facility profiting from existing infrastructure where only minor modifications need to be foreseen. The design of the experimental area and the proton and electron beam lines are shown. The achievable SPS proton bunch properties and their reproducibility have been measured and are presented.

  20. A beam-profile monitor for the BNL Accelerator Test Facility (ATF)

    International Nuclear Information System (INIS)

    Russell, D.P.; McDonald, K.T.

    1989-01-01

    A beam-profile monitor has been designed to diagnose the 5-MeV high-brightness electron beam from the rf gun of the BNL Accelerator Test Facility (ATF). The monitor consists of a phosphor screen viewed by a CCD camera. The video images are digitized and stored by a framegrabber and analyzed by an IBM PC-AT to extract the emittance. Details of the hardware configuration are presented, along with the spatial resolution of the system measured as a function of phosphor-screen thickness. The strategies which will be used to measure the transverse and longitudinal emittances are briefly mentioned. The system should be capable of measuring a transverse geometric emittance of around 1 mm-mrad, as will be typical of the ATF beam. 6 refs., 2 figs

  1. Beam Position Monitor and Energy Analysis at the Fermilab Accelerator Science and Technology Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, David Juarez [Univ. of Guanajuato (Mexico)

    2015-08-01

    Fermilab Accelerator Science and Technology Facility has produced its first beam with an energy of 20 MeV. This energy is obtained by the acceleration at the Electron Gun and the Capture Cavity 2 (CC2). When fully completed, the accelerator will consist of a photoinjector, one International Liner Collider (ILC)-type cryomodule, multiple accelerator R&D beamlines, and a downstream beamline to inject 300 MeV electrons into the Integrable Optics Test Accelerator (IOTA). We calculated the total energy of the beam and the corresponding energy to the Electron Gun and CC2. Subsequently, a Beam Position Monitors (BPM) error analysis was done, to calculate the device actual resolution.

  2. Sustaining neutral beam power supply system for the Mirror Fusion Test Facility

    International Nuclear Information System (INIS)

    Eckard, R.D.; Wilson, J.H.; Van Ness, H.W.

    1980-01-01

    In late August 1978, a fixed price procurement contract for $25,000,000 was awarded to Aydin Energy Division, Palo Alto, California, for the design, manufacture, installation and acceptance testing of the Lawrence Livermore National Laboratory Mirror Fusion Test Facility (MFTF) Sustaining Neutral Beam Power Supply System (SNBPSS). This system of 24 power supply sets will provide the conditioned power for the 24 neutral beam source modules. Each set will provide the accel potential the arc power, the filament power, and the suppressor power for its associated neutral beam source module. The design and development of the SNBPSS has progressed through the final design phase and is now in production. Testing of the major sub-assembly power supply is proceeding at Aydin and the final acceptance testing of the first two power supplies at LLNL is expected to be completed this year

  3. Cavity beam position monitor system for the Accelerator Test Facility 2

    Science.gov (United States)

    Kim, Y. I.; Ainsworth, R.; Aryshev, A.; Boogert, S. T.; Boorman, G.; Frisch, J.; Heo, A.; Honda, Y.; Hwang, W. H.; Huang, J. Y.; Kim, E.-S.; Kim, S. H.; Lyapin, A.; Naito, T.; May, J.; McCormick, D.; Mellor, R. E.; Molloy, S.; Nelson, J.; Park, S. J.; Park, Y. J.; Ross, M.; Shin, S.; Swinson, C.; Smith, T.; Terunuma, N.; Tauchi, T.; Urakawa, J.; White, G. R.

    2012-04-01

    The Accelerator Test Facility 2 (ATF2) is a scaled demonstrator system for final focus beam lines of linear high energy colliders. This paper describes the high resolution cavity beam position monitor (BPM) system, which is a part of the ATF2 diagnostics. Two types of cavity BPMs are used, C-band operating at 6.423 GHz, and S-band at 2.888 GHz with an increased beam aperture. The cavities, electronics, and digital processing are described. The resolution of the C-band system with attenuators was determined to be approximately 250 nm and 1μm for the S-band system. Without attenuation the best recorded C-band cavity resolution was 27 nm.

  4. The Radioactive Ion Beams in Brazil (RIBRAS) facility. Description, program, main results, future plans

    Energy Technology Data Exchange (ETDEWEB)

    Lepine-Szily, A.; Lichtenthaeler, R.; Guimaraes, V. [Instituto de Fisica, Universidade de Sao Paulo (Brazil)

    2014-08-15

    RIBRAS (Radioactive Ion Beams in Brazil) is a facility installed at the Institute of Physics of the University of Sao Paulo (IFUSP), Brazil. The RIBRAS system consists of two superconducting solenoids and uses the ''in-flight method'' to produce radioactive ion beams using the primary beam provided by the 8UD Pelletron Tandem of IFUSP. The ion beams produced so far by RIBRAS are {sup 6}He, {sup 8}Li, {sup 7}Be, {sup 10}Be, {sup 8}B, {sup 12}B with intensities that can vary from 10{sup 4} to 10{sup 6} pps. Initially the experimental program covered the study of elastic and inelastic scattering with the objective to study the interaction potential and the reaction mechanisms between weakly bound (RIB) and halo ({sup 6}He and {sup 8}B) projectiles on light, medium and heavy mass targets. With highly purified beams, the study of resonant elastic scattering and resonant transfer reactions, using inverse kinematics and thick targets, has also been included in our experimental program. Also, transfer reactions of astrophysical interest and fusion reactions induced by halo nuclei are part of the near-future research program. Our recent results on elastic scattering, alpha-particle production and total reaction cross sections, as well as the resonant elastic and transfer reactions, are presented. Our plans for the near future are related to the installation of a new beam line and a cave for gamma-ray detection. We intend to place in operation a large area neutron detector available in our laboratory. The long-range plans could be the move of the RIBRAS system to the more energetic beam line of the LINAC post-accelerator (10MeV/nucleon primary beams) still in construction in our laboratory. (orig.)

  5. The Radioactive Ion Beams in Brazil (RIBRAS) facility. Description, program, main results, future plans

    Science.gov (United States)

    Lépine-Szily, A.; Lichtenthäler, R.; Guimarães, V.

    2014-08-01

    RIBRAS (Radioactive Ion Beams in Brazil) is a facility installed at the Institute of Physics of the University of São Paulo (IFUSP), Brazil. The RIBRAS system consists of two superconducting solenoids and uses the "in-flight method" to produce radioactive ion beams using the primary beam provided by the 8UD Pelletron Tandem of IFUSP. The ion beams produced so far by RIBRAS are 6He, 8Li, 7Be, 10Be, 8B, 12B with intensities that can vary from 104 to 106 pps. Initially the experimental program covered the study of elastic and inelastic scattering with the objective to study the interaction potential and the reaction mechanisms between weakly bound (RIB) and halo (6He and 8B projectiles on light, medium and heavy mass targets. With highly purified beams, the study of resonant elastic scattering and resonant transfer reactions, using inverse kinematics and thick targets, has also been included in our experimental program. Also, transfer reactions of astrophysical interest and fusion reactions induced by halo nuclei are part of the near-future research program. Our recent results on elastic scattering, alpha-particle production and total reaction cross sections, as well as the resonant elastic and transfer reactions, are presented. Our plans for the near future are related to the installation of a new beam line and a cave for gamma-ray detection. We intend to place in operation a large area neutron detector available in our laboratory. The long-range plans could be the move of the RIBRAS system to the more energetic beam line of the LINAC post-accelerator (10MeV/nucleon primary beams) still in construction in our laboratory.

  6. The H line: a brand new beam line for fundamental physics at the J-PARC muon facility

    International Nuclear Information System (INIS)

    Kawamura, N; Shimomura, K; Miyake, Y; Toyoda, A; Saito, N; Mihara, S; Aoki, M

    2013-01-01

    The muon facility, J-PARC (Muon Science Establishment; MUSE), has been operated since first beam in 2008. Starting with a 200 kW proton beam, the beam intensity has reached 3×10 6 / muons/s, the most intense pulsed muon beam in the world. A 2 cm thick graphite target permits the extraction of four secondary muon beams. A brand new beam line, the H line, is planned to be constructed. The new beam line is designed to have a large acceptance, will provide the ability to tune the momentum, and use a kicker magnet and/or Wien filter. This beam line will provide an intense beam for experiments that require high statistics and must occupy the experimental areas for a relatively long period.

  7. Facility to disinfect medical wastes by 10 MeV electron beam

    International Nuclear Information System (INIS)

    Kerluke, D.R.

    1998-01-01

    As regulations related to the disposal of infectious hospital and other medical waste are become increasingly stringent, hospitals and governments worldwide are looking to develop more effective and economical means to disinfect such waste materials prior to them being ultimately landfilled, incinerated or recycled. With the advent of reliable high-energy, high-power industrial electron accelerators, the prospect now exists to centralize collection of much of the infectious medical waste for major metropolitan areas at a single facility, and render it harmless using irradiation. Using much of the same or similar methodologies already developed for single-use medical device sterilization and for bioburden reduction in other goods, high energy electron beam treatment offers unique process advantages which become increasingly attractive with the economies of scale available at higher power. This paper will explore some of the key issues related to the safe disposition of infectious hospital and other medical waste, related irradiation research projects, and the design and economic factors related to an electron beam facility dedicated to this application. This will be presented in the context of the Rhodotron family of electron beam accelerators manufactured by Ion Beam Applications s.a. (author)

  8. Physics at a future Neutrino Factory and super-beam facility

    CERN Document Server

    Bandyopadhyay, A; Gandhi, R; Goswami, S; Roberts, B L; Bouchez, J; Antoniadis, I; Ellis, J; Giudice, G F; Schwetz, T; Umansankar, S; Karagiorgi, G; Aguilar-Arevalo, A; Conrad, J M; Shaevitz, M H; Pascoli, Silvia; Geer, S; Rolinec, M; Blondel, A; Campanelli, M; Kopp, J; Lindner, M; Peltoniemi, J; Dornan, P J; Long, K; Matsushita, T; Rogers, C; Uchida, Y; Dracos, M; Whisnant, K; Casper, D; Chen, Mu-Chun; Popov, B; Aysto, J; Marfatia, D; Okada, Y; Sugiyama, H; Jungmann, K; Lesgourgues, J; Murayama, France H; Zisman, M; Tortola, M A; Friedland, A; Antusch, S; Biggio, C; Donini, A; Fernandez-Martinez, E; Gavela, B; Maltoni, M; Lopez-Pavon, J; Rigolin, S; Mondal, N; Palladino, V; Filthaut, F; Albright, C; de Gouvea, A; Kuno, Y; Nagashima, Y; Mezzetoo, M; Lola, S; Langacker, P; Baldini, A; Nunokawa, H; Meloni, D; Diaz, M; King, S F; Zuber, K; Akeroyd, A G; Grossman, Y; Farzan, Y; Tobe, K; Aoki, Mayumi; Kitazawa, N; Yasuda, O; Petcov, S; Romanino, A; Chimenti, P; Vacchi, A; Smirnov, A Yu; Couce, Italy E; Gomez-Cadenas, J J; Hernandez, P; Sorel, M; Valle, J W F; Harrison, P F; Lundardini, C; Nelson, J K; Barger, V; Everett, L; Huber, P; Winter, W; Fetscher, W; van der Schaaf, A

    2009-01-01

    The conclusions of the Physics Working Group of the international scoping study of a future Neutrino Factory and super-beam facility (the ISS) are presented. The ISS was carried by the international community between NuFact05, (the 7th International Workshop on Neutrino Factories and Superbeams, Laboratori Nazionali di Frascati, Rome, June 21-26, 2005) and NuFact06 (Ivine, California, 24{30 August 2006). The physics case for an extensive experimental programme to understand the properties of the neutrino is presented and the role of high-precision measurements of neutrino oscillations within this programme is discussed in detail. The performance of second generation super-beam experiments, beta-beam facilities, and the Neutrino Factory are evaluated and a quantitative comparison of the discovery potential of the three classes of facility is presented. High-precision studies of the properties of the muon are complementary to the study of neutrino oscillations. The Neutrino Factory has the potential to provide ...

  9. Upgrade of the facility EXOTIC for the in-flight production of light Radioactive Ion Beams

    Energy Technology Data Exchange (ETDEWEB)

    Mazzocco, M., E-mail: marco.mazzocco@pd.infn.it [Dipartimento di Fisica e Astronomia, Universitá di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); INFN-Sezione di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); Torresi, D.; Strano, E. [Dipartimento di Fisica e Astronomia, Universitá di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); INFN-Sezione di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); Boiano, A. [INFN-Sezione di Napoli, Via Cinthia, I-80126 Napoli (Italy); Boiano, C. [INFN-Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy); Costa, L. [INFN-LNL, Viale dell’Università 2, I-35020 Legnaro, PD (Italy); Glodariu, T. [NIPNE, 407 Atomistilor Street, 077125 Magurele (Romania); Guglielmetti, A. [INFN-Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy); Dipartimento di Fisica,Università di Milano, Via Celoria 16, I-20133 Milano (Italy); La Commara, M. [INFN-Sezione di Napoli, Via Cinthia, I-80126 Napoli (Italy); Dipartimento di Scienze Fisiche, Università di Napoli, Via Cinthia, I-80126 Napoli (Italy); Parascandolo, C. [Dipartimento di Fisica e Astronomia, Universitá di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); INFN-Sezione di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); Pierroutsakou, D. [INFN-Sezione di Napoli, Via Cinthia, I-80126 Napoli (Italy); Signorini, C.; Soramel, F. [Dipartimento di Fisica e Astronomia, Universitá di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); INFN-Sezione di Padova, Via F. Marzolo 8, I-35131 Padova (Italy); Stroe, L. [NIPNE, 407 Atomistilor Street, 077125 Magurele (Romania)

    2013-12-15

    Highlights: • Production of in-flight Radioactive Ion Beams via two-body reactions. • Development of a cryogenic gas target. • Event-by-event tracking via Parallel Plate Avalanche Counters (PPACs). -- Abstract: The facility EXOTIC for the in-flight production of light weakly-bound Radioactive Ion Beams (RIBs) has been operating at INFN-LNL since 2004. RIBs are produced via two-body reactions induced by high intensity heavy-ion beams impinging on light gas targets and selected by means of a 30°-dipole bending magnet and a 1-m long Wien filter. The facility has been recently upgraded (i) by developing a cryogenic gas target, (ii) by replacing the power supplies of the middle lenses of the two quadrupole triplets, (iii) by installing two y-steerers and (iv) by placing two Parallel Plate Avalanche Counters upstream the secondary target to provide an event-by-event reconstruction of the position hit on the target. So far, RIBs of {sup 7}Be, {sup 8}B and {sup 17}F in the energy range 3–5 MeV/u have been produced with intensities about 3 × 10{sup 5}, 1.6 × 10{sup 3} and 10{sup 5} pps, respectively. Possible light RIBs (up to Z = 10) deliverable by the facility EXOTIC are also reviewed.

  10. Capability verification of the beam delivery system in the superficially-placed tumor therapy terminal at HIRFL

    International Nuclear Information System (INIS)

    Dai Zhongying; Li Qiang; Xiao Guoqing; Jin Xiaodong; Yan Zheng; Chinese Academy of Sciences, Beijing

    2007-01-01

    The passive beam delivery system in the superficially-placed tumor therapy terminal at Heavy Ion Research Facility in Lanzhou (HIRFL), which includes two orthogonal dipole magnets as scanning system, a motor-driven energy degrader as range-shifter, series of ridge filters as range modulator and a multileaf collimator, is introduced in detail. The capacities of its important components and the whole system have been verified experimentally. The tests of the ridge filter for extending Bragg peak and the range shifter for energy adjustment show both work well. To examine the passive beam delivery system, a beam shaping experiment were carried out, simulating a three-dimensional (3D) conformal irradiation to a tumor. The encouraging experimental result confirms that 3D layer-stacking conformal irradiation can be performed by means of the passive system. The validation of the beam delivery system establishes a substantial basis for upcoming clinical trial for superficially-placed tumors with heavy ions in the therapy terminal at HIRFL. (authors)

  11. Radiological and the other safety aspects in the operation of electron beam facility

    International Nuclear Information System (INIS)

    Loterina, Roel Alamares

    2003-01-01

    The radiological safety aspects of the operation of an electron beam facility in general and the 3 MeV ALURTRON electron beam facility of the Malaysian Institute of Nuclear Technology Research (MINT) in particular were reviewed and evaluated. Evaluation was made based on existing records as well as actual monitoring around facility. Area monitoring results using TLDs are within permissible levels. The maximum reading of 7.29 mSv measured in year 2000 is very low as compared to the annual dose limit of 50 mSv/year. In general, the shielding for the installation is adequate and no significant radiation leakage were detected based on radiation survey results. However, measured radiation levels with a maximum of 1.9 mSv/h at the sampling ports easily exceed the limit of 25μSv/h. The facility is equipped with safety features, such as interlocked system, adequate shielding, engineered safety design of irradiation and accelerator rooms, and accessories such as conveyor system and product handling system. Warning lights and signals are adequately installed around the facility. Other identified hazards that may affect the operator, workers, and personnel were also evaluated based on previous records of monitoring. The ozone concentration levels with a maximum reading of 0.05 ppm measured in the environment of the facility are within the threshold limit value of 0.1 ppm. The measured noise levels at all locations around facility are generally below the maximum permissible level of 80dB. The ALURTRON has achieved a minimum safety requirement to warrant its full operation without relying on administrative controls and procedures to ensure safety in operation. (Auth.)

  12. A conceptual design of neutron tumor therapy reactor facility with a YAYOI based fast neutron source reactor

    International Nuclear Information System (INIS)

    Wakabayashi, Hiroaki; An, Shigehiro.

    1983-01-01

    Fast neutron is known as one of useful radiations for radiation therapy of tumors. Boron neutron capture therapy (BNCT) of tumors which makes use of 10 B(n, α) 7 Li reaction of 10 B compounds selectively attached to tumor cells with thermal and intermediate neutrons is another way of neutron based radiation therapy which is, above all, attractive enough to kill tumor cells selectively sparing normal tissue. In Japan, BNCT has already been applied and leaned to be effective. After more than a decade operational experiences and the specific experiments designed for therapeutical purposes, in this paper, a conceptual design of a special neutron therapy reactor facility based on YAYOI - fast neutron source reactor of Nuclear Engineering Research Laboratory, Faculty of Engineering, the University of Tokyo - modified to provide an upward beam of fast and intermediate neutrons is presented. Emphasis is placed on the in-house nature of facility and on the coordinating capability of biological and physical researches as well as maintenances of the facility. (author)

  13. Faraday cup dosimetry in a proton therapy beam without collimation

    International Nuclear Information System (INIS)

    Grusell, Erik; Isacsson, Ulf; Montelius, Anders; Medin, Joakim

    1995-01-01

    A Faraday cup in a proton beam can give an accurate measurement of the number of protons collected by the cup. It is shown that the collection efficiency with a proper design can be close to unity. To be able to calibrate an ionization chamber from such a measurement, as is recommended in some dosimetry protocols, the energy spectrum of the proton beam must be accurately known. This is normally not the case when the lateral beam extension is defined by collimators. Therefore a method for relating an ionization chamber measurement in an uncollimated beam to the total number of protons in the beam has been developed and is described together with experimental results from calibrating an ionization chamber using this method in the therapeutic beam in Uppsala. This method is applicable to ionization chambers of any shape and the accuracy is estimated to be 1.6% (1 SD). (Author)

  14. Beam dynamics study in the C235 cyclotron for proton therapy

    International Nuclear Information System (INIS)

    Karamysheva, G.A.; Kostromin, S.A.

    2008-01-01

    Study of the beam dynamics in the C235 cyclotron dedicated to the proton therapy is presented. Results of the computer simulations of the particle motion in the measured magnetic field are given. Study of the resonance influence on the acceleration process was carried out. The corresponding tolerances on the magnetic field imperfections and transverse beam parameters were defined using these simulations

  15. Development of a Beam-based Phase Feedforward Demonstration at the CLIC Test Facility (CTF3)

    CERN Document Server

    AUTHOR|(CDS)2083344; Christian, Glenn

    The Compact Linear Collider (CLIC) is a proposal for a future linear electron--positron collider that could achieve collision energies of up to 3~TeV. In the CLIC concept the main high energy beam is accelerated using RF power extracted from a high intensity drive beam, achieving an accelerating gradient of 100~MV/m. This scheme places strict tolerances on the drive beam phase stability, which must be better than $0.2^\\circ$ at 12~GHz. To achieve the required phase stability CLIC proposes a high bandwidth (${>}17.5$~MHz), low latency drive beam ``phase feedforward'' (PFF) system. In this system electromagnetic kickers, powered by 500~kW amplifiers, are installed in a chicane and used to correct the phase by deflecting the beam on to longer or shorter trajectories. A prototype PFF system has been installed at the CLIC Test Facility, CTF3; the design, operation and commissioning of which is the focus of this work. Two kickers have been installed in the pre-existing chicane in the TL2 transfer line at CTF3 for t...

  16. Improvements in electron beam monitoring and heat flux flatness at the JUDITH 2-facility

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Thomas, E-mail: weber.th@gmx.de [Forschungszentrum Jülich, Institute of Energy and Climate Research, Jülich (Germany); Bürger, Andreas; Dominiczak, Karsten; Pintsuk, Gerald [Forschungszentrum Jülich, Institute of Energy and Climate Research, Jülich (Germany); Banetta, Stefano; Bellin, Boris [Fusion for Energy, Josep Pla, 2, Torres Diagonal Litoral B3, 08019 Barcelona (Spain); Mitteau, Raphael; Eaton, Russell [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France)

    2015-10-15

    Highlights: • Monitoring of the much faster electron beam motion by IR camera through a synchronized frame triggering. • Estimation of the heat flux generated by electron beam guns based on calorimetry and FEM simulations. • Consideration of the inclined electron beam loading of rectangular-shaped objects. - Abstract: Three beryllium-armoured small-scale mock-ups and one semi-prototype for the ITER first wall were tested by the electron beam facility JUDITH 2 at Forschungszentrum Jülich. Both testing campaigns with cyclic loads up to 2.5 MW/m{sup 2} are carried out in compliance with the extensive quality and management specifications of ITER Organization (IO) and Fusion for Energy (F4E). Several dedicated calibration experiments were performed before the actual testing in order to fulfil the testing requirements and tolerances. These quality requests have been the motivation for several experimental setup improvements. The most relevant results of these activities, being the electron beam monitoring and the heat flux flatness verification, will be presented.

  17. Development of an external beam nuclear microprobe on the Aglae facility of the Louvre museum

    Energy Technology Data Exchange (ETDEWEB)

    Calligaro, T.; Dran, J.-C. E-mail: dran@culture.fr; Ioannidou, E.; Moignard, B.; Pichon, L.; Salomon, J

    2000-03-01

    The external beam line of our facility has been recently equipped with the focusing system previously mounted on a classical nuclear microprobe. When using a 0.1 {mu}m thick Si{sub 3}N{sub 4} foil for the exit window and flowing helium on the sample under analysis, a beam spot as small as 10 {mu}m is attainable at a distance of 3 mm from the window. Elemental micromapping is performed by mechanical scanning. An electronic device has been designed which allows XY scanning by moving the sample under the beam by steps down to 0.1 {mu}m. Beam monitoring is carried out by means of the weak X-ray signal emitted by the exit foil and detected by a specially designed Si(Li) detector cooled by Peltier effect. The characteristics of external beams of protons and alpha particles are evaluated by means of resonance scanning and elemental mapping of a grid. An example of application is presented, dealing with elemental micro-mapping of inclusions in gemstones.

  18. Improvements in electron beam monitoring and heat flux flatness at the JUDITH 2-facility

    International Nuclear Information System (INIS)

    Weber, Thomas; Bürger, Andreas; Dominiczak, Karsten; Pintsuk, Gerald; Banetta, Stefano; Bellin, Boris; Mitteau, Raphael; Eaton, Russell

    2015-01-01

    Highlights: • Monitoring of the much faster electron beam motion by IR camera through a synchronized frame triggering. • Estimation of the heat flux generated by electron beam guns based on calorimetry and FEM simulations. • Consideration of the inclined electron beam loading of rectangular-shaped objects. - Abstract: Three beryllium-armoured small-scale mock-ups and one semi-prototype for the ITER first wall were tested by the electron beam facility JUDITH 2 at Forschungszentrum Jülich. Both testing campaigns with cyclic loads up to 2.5 MW/m"2 are carried out in compliance with the extensive quality and management specifications of ITER Organization (IO) and Fusion for Energy (F4E). Several dedicated calibration experiments were performed before the actual testing in order to fulfil the testing requirements and tolerances. These quality requests have been the motivation for several experimental setup improvements. The most relevant results of these activities, being the electron beam monitoring and the heat flux flatness verification, will be presented.

  19. Trajectory measurements and correlations in the final focus beam line at the KEK Accelerator Test Facility

    Science.gov (United States)

    Renier, Y.; Bambade, P.; Tauchi, T.; White, G. R.; Boogert, S.

    2013-06-01

    The Accelerator Test Facility 2 (ATF2) commissioning group aims to demonstrate the feasibility of the beam delivery system of the next linear colliders (ILC and CLIC) as well as to define and to test the tuning methods. As the design vertical beam sizes of the linear colliders are about few nanometers, the stability of the trajectory as well as the control of the aberrations are very critical. ATF2 commissioning started in December 2008, and thanks to submicron resolution beam position monitors (BPMs), it has been possible to measure the beam position fluctuation along the final focus of ATF2 during the 2009 runs. The optics was not the nominal one yet, with a lower focusing to make the tuning easier. In this paper, a method to measure the noise of each BPM every pulse, in a model-independent way, will be presented. A method to reconstruct the trajectory’s fluctuations is developed which uses the previously determined BPM resolution. As this reconstruction provides a measurement of the beam energy fluctuations, it was also possible to measure the horizontal and vertical dispersion function at each BPMs parasitically. The spatial and angular dispersions can be fitted from these measurements with uncertainties comparable with usual measurements.

  20. Trajectory measurements and correlations in the final focus beam line at the KEK Accelerator Test Facility

    Directory of Open Access Journals (Sweden)

    Y. Renier

    2013-06-01

    Full Text Available The Accelerator Test Facility 2 (ATF2 commissioning group aims to demonstrate the feasibility of the beam delivery system of the next linear colliders (ILC and CLIC as well as to define and to test the tuning methods. As the design vertical beam sizes of the linear colliders are about few nanometers, the stability of the trajectory as well as the control of the aberrations are very critical. ATF2 commissioning started in December 2008, and thanks to submicron resolution beam position monitors (BPMs, it has been possible to measure the beam position fluctuation along the final focus of ATF2 during the 2009 runs. The optics was not the nominal one yet, with a lower focusing to make the tuning easier. In this paper, a method to measure the noise of each BPM every pulse, in a model-independent way, will be presented. A method to reconstruct the trajectory’s fluctuations is developed which uses the previously determined BPM resolution. As this reconstruction provides a measurement of the beam energy fluctuations, it was also possible to measure the horizontal and vertical dispersion function at each BPMs parasitically. The spatial and angular dispersions can be fitted from these measurements with uncertainties comparable with usual measurements.

  1. Development of a low-energy radioactive ion beam facility for the MARA separator

    Energy Technology Data Exchange (ETDEWEB)

    Papadakis, Philippos, E-mail: philippos.papadakis@jyu.fi; Moore, Iain; Pohjalainen, Ilkka; Sarén, Jan; Uusitalo, Juha [University of Jyväskylä, Department of Physics (Finland)

    2016-12-15

    A low-energy radioactive ion beam facility for the production and study of nuclei produced close to the proton drip line is under development at the Accelerator Laboratory of the University of Jyväskylä, Finland. The facility will take advantage of the mass selectivity of the recently commissioned MARA vacuum-mode mass separator. The ions selected by MARA will be stopped and thermalised in a small-volume gas cell prior to extraction and further mass separation. The gas cell design allows for resonance laser ionisation/spectroscopy both in-gas-cell and in-gas-jet. The facility will include experimental setups allowing ion counting, mass measurement and decay spectroscopy.

  2. Structural integrity assessment based on the HFR Petten neutron beam facilities

    CERN Document Server

    Ohms, C; Idsert, P V D

    2002-01-01

    Neutrons are becoming recognized as a valuable tool for structural-integrity assessment of industrial components and advanced materials development. Microstructure, texture and residual stress analyses are commonly performed by neutron diffraction and a joint CEN/ISO Pre-Standard for residual stress analysis is under development. Furthermore neutrons provide for defects analyses, i.e. precipitations, voids, pores and cracks, through small-angle neutron scattering (SANS) or radiography. At the High Flux Reactor, 12 beam tubes have been installed for the extraction of thermal neutrons for such applications. Two of them are equipped with neutron diffractometers for residual stress and structure determination and have been extensively used in the past. Several other facilities are currently being reactivated and upgraded. These include the SANS and radiography facilities as well as a powder diffractometer. This paper summarizes the main characteristics and current status of these facilities as well as recently in...

  3. Neutron dose equivalent next to the target shield of a neutron therapy facility using an LET counter

    International Nuclear Information System (INIS)

    Stinchcomb, T.G.; Kuchnir, F.T.

    1981-01-01

    The use of a spherical tissue-equivalent proportional counter for measurements of the lineal energy (y) and derivations of the linear energy transfer (LET) for fast neutrons has the advantage of giving distributions of dose and dose equivalent as functions of either LET or y. A measurement next to the target shielding of the neutron therapy facility at the University of Chicago Hospitals and Clinics (UCHC) is described, and the data processing is outlined. The distributions are presented and compared to those from measurements in the neutron beam. The average quality factors are presented

  4. Performance specifications for proton medical facility

    Energy Technology Data Exchange (ETDEWEB)

    Chu, W.T.; Staples, J.W.; Ludewigt, B.A.; Renner, T.R.; Singh, R.P.; Nyman, M.A.; Collier, J.M.; Daftari, I.K.; Petti, P.L.; Alonso, J.R. [Lawrence Berkeley Lab., CA (United States); Kubo, H.; Verhey, L.J. [University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center]|[California Univ., San Francisco, CA (United States). School of Medicine; Castro, J.R. [Lawrence Berkeley Lab., CA (United States)]|[University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center]|[California Univ., San Francisco, CA (United States). School of Medicine

    1993-03-01

    Performance specifications of technical components of a modern proton radiotherapy facility are presented. The technical items specified include: the accelerator; the beam transport system including rotating gantry; the treatment beamline systems including beam scattering, beam scanning, and dosimetric instrumentation; and an integrated treatment and accelerator control system. Also included are treatment ancillary facilities such as diagnostic tools, patient positioning and alignment devices, and treatment planning systems. The facility specified will accommodate beam scanning enabling the three-dimensional conformal therapy deliver .

  5. Establishment of the Neutron Beam Research Facility at the OPAL Reactor

    International Nuclear Information System (INIS)

    Kennedy, S.J.; Robinson, R.A.

    2012-01-01

    Full text: Australia's first research reactor, HIFAR, reached criticality in January 1958. At that time Australia's main agenda was establishment of a nuclear power program. HIFAR operated for nearly 50 years, providing a firm foundation for the establishment of Australia's second generation research Reactor OPAL, which reached criticality in August 006. In HIFAR's early years a neutron beam facility was established for materials characterization, partly in aid of the nuclear energy agenda and partly in response to interest from Australia's scientific community. By the time Australia's nuclear energy program ceased (in the 1970s), radioisotope production and research had also been established at Lucas Heights. Also, by this time the neutron beam facility for scientific research had evolved into a major utilization programme, warranting establishment of an independent body to facilitate scientific access (the Australian Institute for Nuclear Science and Engineering). In HIFAR's lifetime, ANSTO established a radiopharmaceuticals service for the Australian medical community and NDT silicon production was also established and grew to maturity. So when time came to determine the strategy for nuclear research in Australia into the 21st century, it was clear that the replacement for HIFAR should be multipurpose, with major emphases on scientific applications of neutron beams and medical isotope production. With this strategy in mind, ANSTO set about to design and build OPAL with a world-class neutron beam facility, capable of supporting a large and diverse scientific research community. The establishment of the neutron beam facility became the mission of the Bragg Institute management team. This journey began in 1997 with establishment of a working budget, and reached its first major objective when OPAL reached 20 MW thermal power nearly one decade later (in 2006). The first neutron beam instruments began operation soon after (in 2007), and quickly proved themselves to be

  6. Radioactive ion beam production challenges at the Holifield Heavy Ion Research Facility

    International Nuclear Information System (INIS)

    Meigs, M.J.; Alton, G.D.; Dowling, D.T.; Haynes, D.L.; Jones, C.M.; Juras, R.C.; Lane, S.N.; Mills, G.D.; Mosko, S.W.; Olsen, D.K.; Tatum, B.A.

    1992-01-01

    The radioactive ion beam (RIB) project at the Holifield Heavy Ion Research Facility (HHIRF) will provide for reconfiguration of the HHIRF accelerator system to enable provision of low-intensity RIBs for nuclear and astrophysics research. As we have progressed with the design of the reconfiguration, we have encountered several challenges that were not immediately obvious when first contemplating the project. The challenges do not seem insurmountable but should keep life interesting for those of us doing the work. A brief review of the project will allow a better understanding of the challenges in RIB production. Radioactive ion beams will be produced with the Isotope Separator On-Line (ISOL) postacceleration technique. In particular, radioactive atoms will be produced by reactions in the thick stopping target of an ISOL-type target-ion source assembly using intense beams from the Oak Ridge Isochronous Cyclotron equipped with a light-ion internal source. This ISOL target-ion source assembly will be mounted on a high-voltage platform with a mass separator. The target ion source will operate at potentials up to 50 kV with respect to the high voltage platform. The radioactive atoms produced by nuclear reactions in the target diffuse to the surface of the heated target material, desorb from this surface, and effuse through a heated transfer tube into an ion source where ionization and extraction take place. Two types of ion sources will be initially considered. A Forced Electron Beam Induced Arc Discharge source, similar to those used by the ISOLDE facility at CERN and by the UNISOR facility at ORNL, will be built to produce positive ions. These positive ions will be focused through an alkali vapor charge-exchange canal to produce negative ions for tandem injection. In addition, a direct negative surface ionization addition or modification to the above source will be built and investigated

  7. Role of beam orientation optimization in intensity-modulated radiation therapy

    International Nuclear Information System (INIS)

    Pugachev, Andrei; Li, Jonathan G.; Boyer, Arthur L.; Hancock, Steven L.; Le, Quynh-Thu; Donaldson, Sarah S.; Lei Xing

    2001-01-01

    Purpose: To investigate the role of beam orientation optimization in intensity-modulated radiation therapy (IMRT) and to examine the potential benefits of noncoplanar intensity-modulated beams. Methods and Materials: A beam orientation optimization algorithm was implemented. For this purpose, system variables were divided into two groups: beam position (gantry and table angles) and beam profile (beamlet weights). Simulated annealing was used for beam orientation optimization and the simultaneous iterative inverse treatment planning algorithm (SIITP) for beam intensity profile optimization. Three clinical cases were studied: a localized prostate cancer, a nasopharyngeal cancer, and a paraspinal tumor. Nine fields were used for all treatments. For each case, 3 types of treatment plan optimization were performed: (1) beam intensity profiles were optimized for 9 equiangular spaced coplanar beams; (2) orientations and intensity profiles were optimized for 9 coplanar beams; (3) orientations and intensity profiles were optimized for 9 noncoplanar beams. Results: For the localized prostate case, all 3 types of optimization described above resulted in dose distributions of a similar quality. For the nasopharynx case, optimized noncoplanar beams provided a significant gain in the gross tumor volume coverage. For the paraspinal case, orientation optimization using noncoplanar beams resulted in better kidney sparing and improved gross tumor volume coverage. Conclusion: The sensitivity of an IMRT treatment plan with respect to the selection of beam orientations varies from site to site. For some cases, the choice of beam orientations is important even when the number of beams is as large as 9. Noncoplanar beams provide an additional degree of freedom for IMRT treatment optimization and may allow for notable improvement in the quality of some complicated plans

  8. SU-E-T-577: Obliquity Factor and Surface Dose in Proton Beam Therapy

    International Nuclear Information System (INIS)

    Das, I; Andersen, A; Coutinho, L

    2015-01-01

    Purpose: The advantage of lower skin dose in proton beam may be diminished creating radiation related sequalae usually seen with photon and electron beams. This study evaluates the surface dose as a complex function of beam parameters but more importantly the effect of beam angle. Methods: Surface dose in proton beam depends on the beam energy, source to surface distance, the air gap between snout and surface, field size, material thickness in front of surface, atomic number of the medium, beam angle and type of nozzle (ie double scattering, (DS), uniform scanning (US) or pencil beam scanning (PBS). Obliquity factor (OF) is defined as ratio of surface dose in 0° to beam angle Θ. Measurements were made in water phantom at various beam angles using very small microdiamond that has shown favorable beam characteristics for high, medium and low proton energy. Depth dose measurements were performed in the central axis of the beam in each respective gantry angle. Results: It is observed that surface dose is energy dependent but more predominantly on the SOBP. It is found that as SSD increases, surface dose decreases. In general, SSD, and air gap has limited impact in clinical proton range. High energy has higher surface dose and so the beam angle. The OF rises with beam angle. Compared to OF of 1.0 at 0° beam angle, the value is 1.5, 1.6, 1,7 for small, medium and large range respectively for 60 degree angle. Conclusion: It is advised that just like range and SOBP, surface dose should be clearly understood and a method to reduce the surface dose should be employed. Obliquity factor is a critical parameter that should be accounted in proton beam therapy and a perpendicular beam should be used to reduce surface dose

  9. A nuclear physics program at the Rare Isotope Beams Accelerator Facility in Korea

    Directory of Open Access Journals (Sweden)

    Chang-Bum Moon

    2014-02-01

    Full Text Available This paper outlines the new physics possibilities that fall within the field of nuclear structure and astrophysics based on experiments with radioactive ion beams at the future Rare Isotope Beams Accelerator facility in Korea. This ambitious multi-beam facility has both an Isotope Separation On Line (ISOL and fragmentation capability to produce rare isotopes beams (RIBs and will be capable of producing and accelerating beams of wide range mass of nuclides with energies of a few to hundreds MeV per nucleon. The large dynamic range of reaccelerated RIBs will allow the optimization in each nuclear reaction case with respect to cross section and channel opening. The low energy RIBs around Coulomb barrier offer nuclear reactions such as elastic resonance scatterings, one or two particle transfers, Coulomb multiple-excitations, fusion-evaporations, and direct capture reactions for the study of the very neutron-rich and proton-rich nuclides. In contrast, the high energy RIBs produced by in-flight fragmentation with reaccelerated ions from the ISOL enable to explore the study of neutron drip lines in intermediate mass regions. The proposed studies aim at investigating the exotic nuclei near and beyond the nucleon drip lines, and to explore how nuclear many-body systems change in such extreme regions by addressing the following topics: the evolution of shell structure in areas of extreme proton to neutron imbalance; the study of the weak interaction in exotic decay schemes such as beta-delayed two-neutron or two-proton emission; the change of isospin symmetry in isobaric mirror nuclei at the drip lines; two protons or two neutrons radioactivity beyond the drip lines; the role of the continuum states including resonant states above the particle-decay threshold in exotic nuclei; and the effects of nuclear reaction rates triggered by the unbound proton-rich nuclei on nuclear astrophysical processes.

  10. Use of the Power Burst Facility for boron neutron capture therapy

    International Nuclear Information System (INIS)

    Crocker, J.G.; Griebenow, M.L.; Leatham, J.

    1990-01-01

    A program is under development at the Idaho National Engineering Laboratory (INEL) that involves using the Power Burst Facility (PBF) for research into boron neutron capture therapy (BNCT). BNCT utilizes the ionizing energy from boron-neutron capture to stop reproduction of or destroy cells in cancerous tissue in a two-step process. The first step is to selectively concentrate a boron isotope within the tumor cell, that when activated by neutron capture emits highly ionizing, short range particles. The second step involves activation of the isotope only in the vicinity of the tumor with a narrow neutron beam. The ( 10 B[n, 4 He] 7 Li) reaction with thermal neutrons produces fission products with track lengths approximately equal to a cell diameter. The INEL program includes the modification of the PBF by the addition of a filter and treatment area. The filter will down-scatter high energy neutrons into the epithermal range and remove thermal neutrons and excessively damaging gamma components. The intense source of epithermal neutrons from PBF is considered necessary to achieve optimum therapy for deep-seated tumors with minimum damage to surface tissue. THe neutron filter conceptualized for PBF utilizes aluminum and heavy water to down-scatter neutrons into the proper energy range. Bismuth will be used for gamma shielding and cadmium will remove the thermal neutron contaminant from the beam. The INEL program leads to human clinical trials at PBF which are intended to prove that brain tumors can be successfully treated through noninvasive techniques. Further research into BNCT at PBF for other cancer types is also anticipated

  11. Potential applications of fusion neutral beam facilities for advanced material processing

    International Nuclear Information System (INIS)

    Williams, J.M.; Tsai, C.C.; Stirling, W.L.; Whealton, J.H.

    1994-01-01

    Surface processing techniques involving high energy ion implantation have achieved commercial success for semiconductors and biomaterials. However, wider use has been limited in good part by economic factors, some of which are related to the line-of-sight nature of the beam implantation process. Plasma source ion implantation is intended to remove some of the limitations imposed by directionality of beam systems and also to help provide economies of scale. The present paper will outline relevant technologies and areas of expertise that exist at Oak Ridge National Laboratory in relation to possible future needs in materials processing. Experience in generation of plasmas, control of ionization states, pulsed extraction, and sheath physics exists. Contributions to future technology can be made either for the immersion mode or for the extracted beam mode. Existing facilities include the High Power Test Facility, which could conservatively operate at 1 A of continuous current at 100 kV delivered to areas of about 1 m 2 . Higher instantaneous voltages and currents are available with a reduced duty cycle. Another facility, the High Heat Flux Facility can supply a maximum of 60 kV and currents of up to 60 A for 2 s on a 10% duty cycle. Plasmas may be generated by use of microwaves, radio-frequency induction or other methods and plasma properties may be tailored to suit specific needs. In addition to ion implantation of large steel components, foreseeable applications include ion implantation of polymers, ion implantation of Ti alloys, Al alloys, or other reactive surfaces

  12. Imaging and characterization of primary and secondary radiation in ion beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Granja, Carlos, E-mail: carlos.granja@utef.cvut.cz; Opalka, Lukas [Institute of Experimental and Applied Physics, Czech Technical University in Prague (Czech Republic); Martisikova, Maria; Gwosch, Klaus [German Cancer Research Center, Heidelberg (Germany); Jakubek, Jan [Advacam, Prague (Czech Republic)

    2016-07-07

    Imaging in ion beam therapy is an essential and increasingly significant tool for treatment planning and radiation and dose deposition verification. Efforts aim at providing precise radiation field characterization and online monitoring of radiation dose distribution. A review is given of the research and methodology of quantum-imaging, composition, spectral and directional characterization of the mixed-radiation fields in proton and light ion beam therapy developed by the IEAP CTU Prague and HIT Heidelberg group. Results include non-invasive imaging of dose deposition and primary beam online monitoring.

  13. Imaging and characterization of primary and secondary radiation in ion beam therapy

    International Nuclear Information System (INIS)

    Granja, Carlos; Opalka, Lukas; Martisikova, Maria; Gwosch, Klaus; Jakubek, Jan

    2016-01-01

    Imaging in ion beam therapy is an essential and increasingly significant tool for treatment planning and radiation and dose deposition verification. Efforts aim at providing precise radiation field characterization and online monitoring of radiation dose distribution. A review is given of the research and methodology of quantum-imaging, composition, spectral and directional characterization of the mixed-radiation fields in proton and light ion beam therapy developed by the IEAP CTU Prague and HIT Heidelberg group. Results include non-invasive imaging of dose deposition and primary beam online monitoring.

  14. Improving the beam quality of the neutron radiography facility using the SLOWPOKE-2 at the Royal Military College of Canada

    International Nuclear Information System (INIS)

    Lewis, W.J.; Bennett, L.G.I.; Teshima, P.

    1996-01-01

    At the SLOWPOKE-2 Facility at the Royal Military College of Canada, a neutron radiography facility has been designed and installed, and the beam quality has been improved by performing a series of radiographs using American standard for testing and materials (ASTM) E 545 indicators. Other means of determining the progress such as bubble detectors and activation foils were used. Modifications to the nosepiece of the beam tube including shielding and linings for fast neutron and gamma radiation were made. (orig.)

  15. The new vertical neutron beam line at the CERN n-TOF facility design and outlook on the performance

    Energy Technology Data Exchange (ETDEWEB)

    Weiß, C., E-mail: christina.weiss@cern.ch [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Chiaveri, E.; Girod, S.; Vlachoudis, V.; Aberle, O. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Barros, S. [Instituto Tecnológico e Nuclear, Instituto Superior Técnico, Universidade Técnica de Lisboa, Lisboa (Portugal); Bergström, I. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Berthoumieux, E. [Commissariat à l’Énergie Atomique (CEA) Saclay – Irfu, Gif-sur-Yvette (France); Calviani, M. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Guerrero, C.; Sabaté-Gilarte, M. [Universidad de Sevilla (Spain); European Organization for Nuclear Research (CERN), Geneva (Switzerland); Tsinganis, A. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); National Technical University of Athens (NTUA) (Greece); Andrzejewski, J. [Uniwersytet Łódzki, Lodz (Poland); Audouin, L. [Centre National de la Recherche Scientifique/IN2P3 – IPN, Orsay (France); Bacak, M. [Atominstitut, Technische Universität Wien (Austria); Balibrea-Correa, J. [Centro de Investigaciones Energeticas Medioambientales y Tecnológicas (CIEMAT), Madrid (Spain); Barbagallo, M. [Istituto Nazionale di Fisica Nucleare, Bari (Italy); Bécares, V. [Centro de Investigaciones Energeticas Medioambientales y Tecnológicas (CIEMAT), Madrid (Spain); and others

    2015-11-01

    At the neutron time-of-flight facility n-TOF at CERN a new vertical beam line was constructed in 2014, in order to extend the experimental possibilities at this facility to an even wider range of challenging cross-section measurements of interest in astrophysics, nuclear technology and medical physics. The design of the beam line and the experimental hall was based on FLUKA Monte Carlo simulations, aiming at maximizing the neutron flux, reducing the beam halo and minimizing the background from neutrons interacting with the collimator or back-scattered in the beam dump. The present paper gives an overview on the design of the beam line and the relevant elements and provides an outlook on the expected performance regarding the neutron beam intensity, shape and energy resolution, as well as the neutron and photon backgrounds.

  16. Ion-optical studies for a range adaptation method in ion beam therapy using a static wedge degrader combined with magnetic beam deflection

    International Nuclear Information System (INIS)

    Chaudhri, Naved; Saito, Nami; Bert, Christoph; Franczak, Bernhard; Steidl, Peter; Durante, Marco; Schardt, Dieter; Rietzel, Eike

    2010-01-01

    Fast radiological range adaptation of the ion beam is essential when target motion is mitigated by beam tracking using scanned ion beams for dose delivery. Electromagnetically controlled deflection of a well-focused ion beam on a small static wedge degrader positioned between two dipole magnets, inside the beam delivery system, has been considered as a fast range adaptation method. The principle of the range adaptation method was tested in experiments and Monte Carlo simulations for the therapy beam line at the GSI Helmholtz Centre for Heavy Ions Research. Based on the simulations, ion optical settings of beam deflection and realignment of the adapted beam were experimentally applied to the beam line, and additional tuning was manually performed. Different degrader shapes were employed for the energy adaptation. Measured and simulated beam profiles, i.e. lateral distribution and range in water at isocentre, were analysed and compared with the therapy beam values for beam scanning. Deflected beam positions of up to ±28 mm on degrader were performed which resulted in a range adaptation of up to ±15 mm water equivalence (WE). The maximum deviation between the measured adapted range from the nominal range adaptation was below 0.4 mm WE. In experiments, the width of the adapted beam at the isocentre was adjustable between 5 and 11 mm full width at half maximum. The results demonstrate the feasibility/proof of the proposed range adaptation method for beam tracking from the beam quality point of view.

  17. In-beam test of Neutron detector array facility at IUAC

    International Nuclear Information System (INIS)

    Sugathan, P.; Jhingan, A.; Saneesh, S.

    2014-01-01

    A new experimental facility dedicated for the study of fission dynamics has been installed and commissioned recently at Inter University Accelerator Centre (IUAC), New Delhi. The facility, National Array of Neutron Detectors (NAND) is used for the systematic studies on fission dynamics around Coulomb barrier energies using heavy ion beams from the Tandem plus LINAC accelerator facilities. The detector array consists 100 neutron detectors mounted on a geodesic dome structure at a radial distance of 175 cm from the target and multi wire proportional counters (MWPC) for detection of fission fragments. Each neutron detector is made of 5'' x 5'' cylindrical cell filled with BC501A organic liquid scintillator and coupled to a 5'' photo multiplier tube. A 100 cm diameter spherical vacuum chamber has been installed at the center of the array to house the targets, fission fragment detectors and other ancillary charged particle detectors. The vacuum chamber is made of 4mm thick steel and has target ladder with linear and rotary movements. The detector array is installed on a dedicated beam line of LINAC accelerator facilities at beam hall II. The neutrons are discriminated from gamma rays using pulse shape discrimination (PSD) technique based on conventional analog electronics and the energies of neutrons are measured by the time of flight (TOF) method. For this purpose, custom made electronics modules have been built to process signal from each detector. This module contains the integrated electronics for n - γ discrimination, time of flight (TOF) and light output. The fission fragments are detected in low pressure MWPCs mounted inside the spherical vacuum chamber. The MWPC has been built based on the conventional design using three electrodes, having a central cathode foil electrode sandwiched between two position sensing anode wire/strip frames. In order to acquire data from detector array, the data acquisition system has been implemented using VME based hardware systems

  18. Proposal of cancer therapy system without rotating gantry

    International Nuclear Information System (INIS)

    Kodaira, Masanobu

    2002-01-01

    Beam therapy is one of useful methods for cancer therapy. Many results in National Institute of Radiological Sciences (NIRS) show many abilities of beam therapy for cancer therapy. In Japan, several beam therapy facilities are constructed or under construction. If its construction budget becomes to be smaller, beam therapy may be used as the general cancer therapy. But in the present beam therapy facilities, the budget of its construction is very large. One of the reasons of big budget is the construction of the big buildings equipped with thick shielding walls. Most of space of the facilities with thick shielding walls is devoted to the treatment equipments such as rotating gantries and beam transport lines. This proposal is that using oblique beam line and rotating treatment bed, multi-portal irradiation is realized without rotating gantry. At the same time, we designed adequate beam lines to minimize the total facilities. (author)

  19. Proton beam therapy: reliability of the synchrocyclotron at the Harvard Cyclotron Laboratory

    International Nuclear Information System (INIS)

    Sisterson, J.M.; Cascio, E.; Koehler, A.M.; Johnson, K.N.

    1991-01-01

    The reliability of the synchrocyclotron at Harvard Cyclotron Laboratory has been studied over the period 1980-1989 to see if proton beam therapy can compare in reliability to linear accelerators used in radiation therapy departments. Breakdowns in relation to patient load are reviewed in outline. (U.K.)

  20. Novel imaging and quality assurance techniques for ion beam therapy a Monte Carlo study

    CERN Document Server

    Rinaldi, I; Jäkel, O; Mairani, A; Parodi, K

    2010-01-01

    Ion beams exhibit a finite and well defined range in matter together with an “inverted” depth-dose profile, the so-called Bragg peak. These favourable physical properties may enable superior tumour-dose conformality for high precision radiation therapy. On the other hand, they introduce the issue of sensitivity to range uncertainties in ion beam therapy. Although these uncertainties are typically taken into account when planning the treatment, correct delivery of the intended ion beam range has to be assured to prevent undesired underdosage of the tumour or overdosage of critical structures outside the target volume. Therefore, it is necessary to define dedicated Quality Assurance procedures to enable in-vivo range verification before or during therapeutic irradiation. For these purposes, Monte Carlo transport codes are very useful tools to support the development of novel imaging modalities for ion beam therapy. In the present work, we present calculations performed with the FLUKA Monte Carlo code and pr...

  1. Performance and beam characteristics of the PANTAK THERAPAX HF225 X-ray therapy machine

    Energy Technology Data Exchange (ETDEWEB)

    Yiannakkaras, C; Papadopoulos, N; Christodoulides, G [Department of Medical Physics, Nicosia General Hospital, 1450 Nicosia (Cyprus)

    1999-12-31

    The performance and beam characteristics of the new PANTAK THERAPAX HF225 X-ray therapy machine have been measured, evaluated and discussed. Eight beam qualities within the working range of generating potentials between 50 and 225 kVp are used in our department. These beam qualities have been investigated in order to provide a data base specific to our machine. Beam Quality, Central Axis Depth Dose, Output, Relative Field Uniformity and Timer Error were investigated. (authors) 11 refs., 4 figs., 9 tabs.

  2. Potential clinical impact of laser-accelerated beams in cancer ion therapy

    Energy Technology Data Exchange (ETDEWEB)

    Obcemea, Ceferino

    2016-09-01

    In this article, I present three advantages of plasma-accelerated ion beams for cancer therapy. I discuss how: 1. low-emittance and well-collimated beams are advantageous in proximal normal tissue-sparing; 2. highly-peaked quasi-monoenergetic beams are ideal for fast energy selection and switching in Pencil Beam Scanning (PBS) as a treatment delivery; 3. high fluence and ultra-short pulse delivery produce collective excitations in the medium and enhance the stopping power. This in turn produces denser ionization track signatures (spurs, blobs, etc.) in target tumors, higher linear energy transfer, higher Bragg peak, and higher radiobiological effectiveness at the micro-level.

  3. Thin and thick targets for radioactive ion beam production at SPIRAL1 facility

    Science.gov (United States)

    Jardin, P.; Bajeat, O.; Delahaye, P.; Dubois, M.; Kuchi, V.; Maunoury, L.

    2018-05-01

    The upgrade of the Système de Production d'Ions Radioactifs Accélérés en Ligne (SPIRAL1) facility will deliver its new Radioactive Ion Beams (RIB) by summer 2017. The goal of the upgrade is an improvement of the performances of the installation in terms of isotopes species and ion charge states [1]. Ion beams are produced using the Isotope Separator On Line Method, consisting in an association of a primary beam of stable ions, a hot target and an ion source. The primary beam impinges on the material of the target. Radioactive isotopes are produced by nuclear reactions and propagate up to the source, where they are ionized and accelerated to create a RIB. One advantage of SPIRAL1 driver is the variety of its available primary beams, from carbon to uranium with energies up to 95 MeV/A. Within the SPIRAL1 upgrade, they will be combined with targets made of a large choice of materials, extending in this way the number of possible nuclear reactions (fusion-evaporation, transfer, fragmentation) for producing a wider range of isotopes, up to regions of the nuclide chart still scarcely explored. Depending on the reaction process, on the collision energy and on the primary beam power, thin and thick targets are used. As their functions can be different, their design must cope with specific constraints which will be described. After a presentation of the goals of present and future SPIRAL1 Target Ion Source System, the main target features, studies and designs under progress are presented.

  4. Beamlines of the biomedical imaging and therapy facility at the Canadian light source - part 3

    Science.gov (United States)

    Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka; Thomlinson, William

    2015-03-01

    The BioMedical Imaging and Therapy (BMIT) facility provides synchrotron-specific imaging and radiation therapy capabilities [1-4]. We describe here the Insertion Device (ID) beamline 05ID-2 with the beam terminated in the SOE-1 (Secondary Optical Enclosure) experimental hutch. This endstation is designed for imaging and therapy research primarily in animals ranging in size from mice to humans to horses, as well as tissue specimens including plants. Core research programs include human and animal reproduction, cancer imaging and therapy, spinal cord injury and repair, cardiovascular and lung imaging and disease, bone and cartilage growth and deterioration, mammography, developmental biology, gene expression research as well as the introduction of new imaging methods. The source for the ID beamline is a multi-pole superconducting 4.3 T wiggler [5]. The high field gives a critical energy over 20 keV. The high critical energy presents shielding challenges and great care must be taken to assess shielding requirements [6-9]. The optics in the POE-1 and POE-3 hutches [4,10] prepare a monochromatic beam that is 22 cm wide in the last experimental hutch SOE-1. The double crystal bent-Laue or Bragg monochromator, or the single-crystal K-edge subtraction (KES) monochromator provide an energy range appropriate for imaging studies in animals (20-100+ keV). SOE-1 (excluding the basement structure 4 m below the experimental floor) is 6 m wide, 5 m tall and 10 m long with a removable back wall to accommodate installation and removal of the Large Animal Positioning System (LAPS) capable of positioning and manipulating animals as large as a horse [11]. This end-station also includes a unique detector positioner with a vertical travel range of 4.9 m which is required for the KES imaging angle range of +12.3° to -7.3°. The detector positioner also includes moveable shielding integrated with the safety shutters. An update on the status of the other two end-stations at BMIT, described

  5. Beamlines of the biomedical imaging and therapy facility at the Canadian light source – part 3

    International Nuclear Information System (INIS)

    Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka; Thomlinson, William

    2015-01-01

    The BioMedical Imaging and Therapy (BMIT) facility provides synchrotron-specific imaging and radiation therapy capabilities [1–4]. We describe here the Insertion Device (ID) beamline 05ID-2 with the beam terminated in the SOE-1 (Secondary Optical Enclosure) experimental hutch. This endstation is designed for imaging and therapy research primarily in animals ranging in size from mice to humans to horses, as well as tissue specimens including plants. Core research programs include human and animal reproduction, cancer imaging and therapy, spinal cord injury and repair, cardiovascular and lung imaging and disease, bone and cartilage growth and deterioration, mammography, developmental biology, gene expression research as well as the introduction of new imaging methods. The source for the ID beamline is a multi-pole superconducting 4.3 T wiggler [5]. The high field gives a critical energy over 20 keV. The high critical energy presents shielding challenges and great care must be taken to assess shielding requirements [6–9]. The optics in the POE-1 and POE-3 hutches [4,10] prepare a monochromatic beam that is 22 cm wide in the last experimental hutch SOE-1. The double crystal bent-Laue or Bragg monochromator, or the single-crystal K-edge subtraction (KES) monochromator provide an energy range appropriate for imaging studies in animals (20–100+ keV). SOE-1 (excluding the basement structure 4 m below the experimental floor) is 6 m wide, 5 m tall and 10 m long with a removable back wall to accommodate installation and removal of the Large Animal Positioning System (LAPS) capable of positioning and manipulating animals as large as a horse [11]. This end-station also includes a unique detector positioner with a vertical travel range of 4.9 m which is required for the KES imaging angle range of +12.3° to –7.3°. The detector positioner also includes moveable shielding integrated with the safety shutters. An update on the status of the other two end-stations at BMIT

  6. Beamlines of the biomedical imaging and therapy facility at the Canadian light source – part 3

    Energy Technology Data Exchange (ETDEWEB)

    Wysokinski, Tomasz W., E-mail: bmit@lightsource.ca [Canadian Light Source, Saskatoon, SK (Canada); Chapman, Dean [Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK (Canada); Adams, Gregg [Western College of Veterinary Medicine, Saskatoon, SK (Canada); Renier, Michel [European Synchrotron Radiation Facility, Grenoble (France); Suortti, Pekka [Department of Physics, University of Helsinki (Finland); Thomlinson, William [Department of Physics, University of Saskatchewan, Saskatoon, SK (Canada)

    2015-03-01

    The BioMedical Imaging and Therapy (BMIT) facility provides synchrotron-specific imaging and radiation therapy capabilities [1–4]. We describe here the Insertion Device (ID) beamline 05ID-2 with the beam terminated in the SOE-1 (Secondary Optical Enclosure) experimental hutch. This endstation is designed for imaging and therapy research primarily in animals ranging in size from mice to humans to horses, as well as tissue specimens including plants. Core research programs include human and animal reproduction, cancer imaging and therapy, spinal cord injury and repair, cardiovascular and lung imaging and disease, bone and cartilage growth and deterioration, mammography, developmental biology, gene expression research as well as the introduction of new imaging methods. The source for the ID beamline is a multi-pole superconducting 4.3 T wiggler [5]. The high field gives a critical energy over 20 keV. The high critical energy presents shielding challenges and great care must be taken to assess shielding requirements [6–9]. The optics in the POE-1 and POE-3 hutches [4,10] prepare a monochromatic beam that is 22 cm wide in the last experimental hutch SOE-1. The double crystal bent-Laue or Bragg monochromator, or the single-crystal K-edge subtraction (KES) monochromator provide an energy range appropriate for imaging studies in animals (20–100+ keV). SOE-1 (excluding the basement structure 4 m below the experimental floor) is 6 m wide, 5 m tall and 10 m long with a removable back wall to accommodate installation and removal of the Large Animal Positioning System (LAPS) capable of positioning and manipulating animals as large as a horse [11]. This end-station also includes a unique detector positioner with a vertical travel range of 4.9 m which is required for the KES imaging angle range of +12.3° to –7.3°. The detector positioner also includes moveable shielding integrated with the safety shutters. An update on the status of the other two end-stations at BMIT

  7. The neutral beam test facility cryopumping operation: preliminary analysis and design of the cryogenic system

    International Nuclear Information System (INIS)

    Gravil, B.; Henry, D.; Cordier, J.J.; Hemsworth, R.; Van Houtte, D.

    2004-01-01

    The ITER neutral beam heating and current drive system is to be equipped with a cryosorption cryopump made up of 12 panels connected in parallel, refrigerated by 4.5 K 0.4 MPa supercritical helium. The pump is submitted to a non homogeneous flux of H 2 or D 2 molecules, and the absorbed flux varies from 3 Pa.m -3 .s -1 to 35 Pa.m -3 .s -1 . In the frame of the 'ITER first injector and test facility CSU-EFDA task' (TW3-THHN-IITF1), the ITER reference cryo-system and cryo-plant designs have been assessed and compared to optimised designs devoted to the Neutral Beam Test Facility (NBTF). The 4.5 K cryo-panel, which has a mass of about 1000 kg, must be periodically regenerated up to 90 K and occasionally to 470 K. The cool-down time after regeneration depends strongly on the refrigeration capacity. Fast regeneration and cool-down of the cryo-panels are not considered a priority for the test facility operation, and an analysis of the consequences of a limited cold power refrigerator on the cooling down time has been carried out and will be discussed. This paper presents a preliminary evaluation of the NBTF cryo-plant and the associated process flow diagram. (authors)

  8. Progress in the realization of the PRIMA neutral beam test facility

    Science.gov (United States)

    Toigo, V.; Boilson, D.; Bonicelli, T.; Piovan, R.; Hanada, M.; Chakraborty, A.; Agarici, G.; Antoni, V.; Baruah, U.; Bigi, M.; Chitarin, G.; Dal Bello, S.; Decamps, H.; Graceffa, J.; Kashiwagi, M.; Hemsworth, R.; Luchetta, A.; Marcuzzi, D.; Masiello, A.; Paolucci, F.; Pasqualotto, R.; Patel, H.; Pomaro, N.; Rotti, C.; Serianni, G.; Simon, M.; Singh, M.; Singh, N. P.; Svensson, L.; Tobari, H.; Watanabe, K.; Zaccaria, P.; Agostinetti, P.; Agostini, M.; Andreani, R.; Aprile, D.; Bandyopadhyay, M.; Barbisan, M.; Battistella, M.; Bettini, P.; Blatchford, P.; Boldrin, M.; Bonomo, F.; Bragulat, E.; Brombin, M.; Cavenago, M.; Chuilon, B.; Coniglio, A.; Croci, G.; Dalla Palma, M.; D'Arienzo, M.; Dave, R.; De Esch, H. P. L.; De Lorenzi, A.; De Muri, M.; Delogu, R.; Dhola, H.; Fantz, U.; Fellin, F.; Fellin, L.; Ferro, A.; Fiorentin, A.; Fonnesu, N.; Franzen, P.; Fröschle, M.; Gaio, E.; Gambetta, G.; Gomez, G.; Gnesotto, F.; Gorini, G.; Grando, L.; Gupta, V.; Gutierrez, D.; Hanke, S.; Hardie, C.; Heinemann, B.; Kojima, A.; Kraus, W.; Maeshima, T.; Maistrello, A.; Manduchi, G.; Marconato, N.; Mico, G.; Moreno, J. F.; Moresco, M.; Muraro, A.; Muvvala, V.; Nocentini, R.; Ocello, E.; Ochoa, S.; Parmar, D.; Patel, A.; Pavei, M.; Peruzzo, S.; Pilan, N.; Pilard, V.; Recchia, M.; Riedl, R.; Rizzolo, A.; Roopesh, G.; Rostagni, G.; Sandri, S.; Sartori, E.; Sonato, P.; Sottocornola, A.; Spagnolo, S.; Spolaore, M.; Taliercio, C.; Tardocchi, M.; Thakkar, A.; Umeda, N.; Valente, M.; Veltri, P.; Yadav, A.; Yamanaka, H.; Zamengo, A.; Zaniol, B.; Zanotto, L.; Zaupa, M.

    2015-08-01

    The ITER project requires additional heating by two neutral beam injectors, each accelerating to 1 MV a 40 A beam of negative deuterium ions, to deliver to the plasma a power of about 17 MW for one hour. As these requirements have never been experimentally met, it was recognized as necessary to setup a test facility, PRIMA (Padova Research on ITER Megavolt Accelerator), in Italy, including a full-size negative ion source, SPIDER, and a prototype of the whole ITER injector, MITICA, aiming to develop the heating injectors to be installed in ITER. This realization is made with the main contribution of the European Union, through the Joint Undertaking for ITER (F4E), the ITER Organization and Consorzio RFX which hosts the Test Facility. The Japanese and the Indian ITER Domestic Agencies (JADA and INDA) participate in the PRIMA enterprise; European laboratories, such as IPP-Garching, KIT-Karlsruhe, CCFE-Culham, CEA-Cadarache and others are also cooperating. Presently, the assembly of SPIDER is on-going and the MITICA design is being completed. The paper gives a general overview of the test facility and of the status of development of the MITICA and SPIDER main components at this important stage of the overall development; then it focuses on the latest and most critical issues, regarding both physics and technology, describing the identified solutions.

  9. The KAERI laser facility with temporal laser beam shaping for application's user

    International Nuclear Information System (INIS)

    Hong, Sung Ki; Kim, Min Suk; Kim, Young Won; Ko, Kwanghoon; Lim, Changhwan; Seo, Young Seok

    2008-01-01

    The Korea Atomic Energy Research Institute(KAERI)has been developed a high energy Nd:Glass laser facility(KLF)for fast ignition research and high energy physics applications at early 2008. Now, we are researching the temporal laser beam shaping for application's user. The temporal laser beam shaping has been applied to a number of industrial applications. The KLF beam shaping system with fiber based consists of two electro optic modulator with DC bias using a Mach Zehnder interferometer, an arbitrary electronic waveform generator, a continuous wavelength fiber laser source, a fiber based pulse amplification system and DC bias source to generate temporally shaped pulses with a high extinction ratio and high resolution. RF signal waveform user defined by an arbitrary electronic waveform generator is only connected to one electro optic modulator. DC bias source with auto feed back or manual controller is connected both two electro optic modulators. Emitting laser light from a continuous wavelength fiber laser source is modulated to meet a user defined laser pulse with a high extinction ratio by two electro optic modulators. Experimental results are shown in Fig.1. Figure 1(a)shows two programmed waveforms with the signal width 10ns in an arbitrary electronic waveform generator. Figure 1(b)shows output laser pulses with sub mJ energy from amplification results of the KLF beam shaping system which can control the pulse width ranges from 400ps to sub us

  10. The beam slow extraction from a magnetic ring of Moscow meson facility

    International Nuclear Information System (INIS)

    Gusev, O.A.; Malitsky, N.D.; Severgin, Yu.P.; Titov, V.A.; Shukeilo, I.A.; Aseev, V.N.; Grachev, M.I.; Lobashev, V.M.; Ostroumov, P.N.; Ponomaryov, O.V.

    1990-01-01

    The beam slow extraction from the circular accelerators or stretcher rings is generally realized by the resonant excitation of betratron oscillations. A precise betatron frequency control is proved to be quite necessary for high-efficient slow ejection. The Coulomb field turns out to have a significant influence upon the slow extraction from the high-current medium energy proton storage rings. It prevents resonant excitation at a reasonable rate and reduces the ejection efficiency. The proton storage ring of Moscow meson facility is an example of a stretcher with a noticeable beam space charge. The detailed investigation of the resonant ejection, having been performed for our stretcher, resulted in the conclusion that extracted beam average current should be limited by the value of 50 mA, which is only 10% of the linac design current. The search for the alternative version to the resonant ejection made us to analyze in details and to develop an old-fashioned method, based on the radial betatron oscillation excitation while the beam is being gradually shifted onto the thin target. (author) 5 refs., 4 figs

  11. The measurement, control, and validation of critical parameters in an electron beam sterilization facility

    International Nuclear Information System (INIS)

    Burns, P.; Drewell, N.H.; McKeown, J.

    1996-01-01

    The delivery and validation of a specified dose to a medical device are key concerns of operators of electron beam irradiation facilities. In an IMPELA-based irradiator, four of the parameters that directly influence the absorbed dose distribution in the product are controllable in real time - the electron energy, average beam current, scanned area, and the product exposure time. The 10 MeV accelerator operates at 50 kW with a stream of 200 μs wide, 100 mA pulses at a repetition rate of 250 Hz. The combination of short-term intra-pulse regulation with long-term pulse-to-pulse stability makes the IMPELA output attractive for the sterilization of medical products. The measurement and closed-loop control techniques used in the IMPELA design will be described with reference to facilitating compliance with medical sterilization standards. (orig.)

  12. Beam line 4: A dedicated surface science facility at Daresbury Laboratory

    International Nuclear Information System (INIS)

    Dhanak, V.R.; Robinson, A.W.; van der Laan, G.; Thornton, G.

    1992-01-01

    We describe a beam line currently under construction at the Daresbury Laboratory which forms part of a surface science research facility for the Interdisciplinary Research Centre in Surface Science. The beam line has three branches, two of which are described here. The first branch covers the high-energy range 640 eV≤hν≤10 keV, being equipped with a double-crystal monochromator and a novel multicoated premirror system. The second branch line is optimized for the energy range 15≤hν≤250 eV, using cylindrical focusing mirrors, a spherical diffraction grating and an ellipsoidal refocusing mirror to achieve high resolution with a small spot size

  13. Numerical analysis of the beam position monitor pickup for the Iranian light source facility

    Energy Technology Data Exchange (ETDEWEB)

    Shafiee, M., E-mail: mehdish@ipm.ir [Radiation Applications Department, Shahid Beheshti University, G. C., Tehran (Iran, Islamic Republic of); Feghhi, S.A.H. [Radiation Applications Department, Shahid Beheshti University, G. C., Tehran (Iran, Islamic Republic of); Rahighi, J. [Iranian Light Source Facility (ILSF), Institute for Research in Fundamental Sciences (IPM), Tehran (Iran, Islamic Republic of)

    2017-03-01

    In this paper, we describe the design of a button type Beam Position Monitor (BPM) for the low emittance storage ring of the Iranian Light Source Facility (ILSF). First, we calculate sensitivities, induced power and intrinsic resolution based on solving Laplace equation numerically by finite element method (FEM), in order to find the potential at each point of BPM's electrode surface. After the optimization of the designed BPM, trapped high order modes (HOM), wakefield and thermal loss effects are calculated. Finally, after fabrication of BPM, it is experimentally tested by using a test-stand. The results depict that the designed BPM has a linear response in the area of 2×4 mm{sup 2} inside the beam pipe and the sensitivity of 0.080 and 0.087 mm{sup −1} in horizontal and vertical directions. Experimental results also depict that they are in a good agreement with numerical analysis.

  14. Radioactive ion beam facility at Louvain-La-Neuve, Belgium and its features

    International Nuclear Information System (INIS)

    Chintalapudi, S.N.

    1991-01-01

    Use of radioactive ion beams for the study of nuclear structure as well as the astrophysical reaction cross sections become the current interest in physics. A full-fledged facility based on two coupled cyclotrons comprising a compact high current cyclotron and a medium energy cyclotron with an intermediate target and ion source system has been recently commissioned at the Louvain-La-Neuve University in Belgium by its accelerator group and has been successfully used for the measurement of cross sections for the primordial nucleosynthesis reactions of astrophysical interest, directly. A brief description of the system, its operational features together with some details of the target and the ion source arrangement for the production of the radioactive ion beams and their acceleration to energies required for the proposed studies is presented. Description of the reactions studied by the Louvain La Neuve group for astrophysical interest is also given. (author). 20 refs., 6 figs., 4 tabs

  15. Measurements of electron beam emittance in the Accelerator Test Facility damping ring operated in multibunch modes

    Directory of Open Access Journals (Sweden)

    Yosuke Honda

    2003-09-01

    Full Text Available We present the measurement results of electron beam emittance in the Accelerator Test Facility damping ring operated in multibunch modes. The measurements were carried out with an upgraded laser wire beam profile monitor. The monitor has now a vertical wire as well as a horizontal one and is able to make much faster measurements thanks to an increased effective laser power inside the cavity. The measured emittance shows no large bunch-to-bunch dependence in either the horizontal or vertical directions. The values of the vertical emittance are similar to those obtained in the single-bunch operation. The present results are an important step toward the realization of a high-energy linear collider.

  16. Longitudinal beam instability due to the ring impedance at KEK's accelerator test facility damping ring

    International Nuclear Information System (INIS)

    Kim, Eun-San

    2003-01-01

    This paper shows the results of a numerical study of the impedance in the Accelerator Test Facility damping ring. The longitudinal impedance in the damping ring is shown to be inductive. It is shown that the total impedance |Z || /n| is 0.23 Ω and the inductance is L = 14 nH. In the extremely low emittance beam of the damping ring, bunch lengthening is caused by both the effects of potential-well distortion and intra-beam scattering. In this paper, the bunch-lengthening due to the ring impedance is numerically investigated, and the result shows qualitative agreement with the result of an analysis performed using the bunch-length measurement. With the calculated longitudinal impedance, the instability threshold in the damping ring is estimated to be a bunch population of 3.3 x 10 10 by using both a Vlasov equation approach and a multi-particle tracking method.

  17. Fast control and data acquisition in the neutral beam test facility

    International Nuclear Information System (INIS)

    Luchetta, A.; Manduchi, G.; Taliercio, C.

    2014-01-01

    Highlights: • The paper describes the fast control and data acquisition in the ITER neutral beam test facility. • The usage of real time control in ion beam generation and extraction is proposed. • Real time management of breakdowns is described. • The implementation of event-driven data acquisition is reported. - Abstract: Fast control and data acquisition are required in the ion source test bed of the ITER neutral beam test facility, referred to as SPIDER. Fast control will drive the operation of the power supply systems with particular reference to special asynchronous events, such as the breakdowns. These are short-circuits among grids or between grids and vessel that can occur repeatedly during beam operation. They are normal events and, as such, they will be managed by the fast control system. Cycle time associated to such fast control is down to hundreds of microseconds. Fast data acquisition is required when breakdowns occur. Event-driven data acquisition is triggered in real time by fast control at the occurrence of each breakdown. Pre- and post-event samples are acquired, allowing capturing information on transient phenomena in a whole time-window centered on the event. Sampling rate of event-driven data acquisition is up to 5 MS/s. Fast data acquisition may also be independent of breakdowns as in the case of the cavity ring-down spectroscopy where data chunks are acquired at 100 MS/s in bursts of 1.5 ms every 100 ms and are processed in real time to produce derived measurements. The paper after the description of the SPIDER fast control and data acquisition application will report the system design based on commercially available hardware and the MARTe and MDSplus software frameworks. The results obtained by running a full prototype of the fast control and data acquisition system are also reported and discussed. They demonstrate that all SPIDER fast control and data acquisition requirements can be met in the prototype solution

  18. Fast control and data acquisition in the neutral beam test facility

    Energy Technology Data Exchange (ETDEWEB)

    Luchetta, A., E-mail: adriano.luchetta@igi.cnr.it; Manduchi, G.; Taliercio, C.

    2014-05-15

    Highlights: • The paper describes the fast control and data acquisition in the ITER neutral beam test facility. • The usage of real time control in ion beam generation and extraction is proposed. • Real time management of breakdowns is described. • The implementation of event-driven data acquisition is reported. - Abstract: Fast control and data acquisition are required in the ion source test bed of the ITER neutral beam test facility, referred to as SPIDER. Fast control will drive the operation of the power supply systems with particular reference to special asynchronous events, such as the breakdowns. These are short-circuits among grids or between grids and vessel that can occur repeatedly during beam operation. They are normal events and, as such, they will be managed by the fast control system. Cycle time associated to such fast control is down to hundreds of microseconds. Fast data acquisition is required when breakdowns occur. Event-driven data acquisition is triggered in real time by fast control at the occurrence of each breakdown. Pre- and post-event samples are acquired, allowing capturing information on transient phenomena in a whole time-window centered on the event. Sampling rate of event-driven data acquisition is up to 5 MS/s. Fast data acquisition may also be independent of breakdowns as in the case of the cavity ring-down spectroscopy where data chunks are acquired at 100 MS/s in bursts of 1.5 ms every 100 ms and are processed in real time to produce derived measurements. The paper after the description of the SPIDER fast control and data acquisition application will report the system design based on commercially available hardware and the MARTe and MDSplus software frameworks. The results obtained by running a full prototype of the fast control and data acquisition system are also reported and discussed. They demonstrate that all SPIDER fast control and data acquisition requirements can be met in the prototype solution.

  19. Gas delivery system and beamline studies for the test beam facility of the Collider Detector at Fermilab

    International Nuclear Information System (INIS)

    Franke, H.G. III.

    1987-12-01

    A fixed-target test beam facility has been designed and constructed at the Meson Test (MT) site to support studies of components of the Collider Detector at Fermi National Accelerator Laboratory (CDF). I assisted in the design and constuction of the test beam facility gas delivery system, and I conducted the initial studies to document the ability of the MT beamline to meet the needs of CDF. Analysis of the preliminary performance data on MT beamline components and beam tunes at required particle energies is presented. Preliminary studies show that the MT beamline has the necessary flexibility to satisfy most CDF requirements now

  20. An assessment of the secondary neutron dose in the passive scattering proton beam facility of the national cancer center

    Energy Technology Data Exchange (ETDEWEB)

    Han, Sang Eun [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Cho, Gyuseong [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Lee, Se Byeong [Proton Therapy Center, National Cancer Center, Goyang (Korea, Republic of)

    2017-06-15

    The purpose of this study is to assess the additional neutron effective dose during passive scattering proton therapy. Monte Carlo code (Monte Carlo N-Particle 6) simulation was conducted based on a precise modeling of the National Cancer Center's proton therapy facility. A three-dimensional neutron effective dose profile of the interior of the treatment room was acquired via a computer simulation of the 217.8-MeV proton beam. Measurements were taken with a 3He neutron detector to support the simulation results, which were lower than the simulation results by 16% on average. The secondary photon dose was about 0.8% of the neutron dose. The dominant neutron source was deduced based on flux calculation. The secondary neutron effective dose per proton absorbed dose ranged from 4.942 ± 0.031 mSv/Gy at the end of the field to 0.324 ± 0.006 mSv/Gy at 150 cm in axial distance.

  1. Designing a range modulator wheel to spread-out the Bragg peak for a passive proton therapy facility

    International Nuclear Information System (INIS)

    Jia, S. Bijan; Romano, F.; Cirrone, Giuseppe A.P.; Cuttone, G.; Hadizadeh, M.H.; Mowlavi, A.A.; Raffaele, L.

    2016-01-01

    In proton beam therapy, a Spread-Out Bragg peak (SOBP) is used to establish a uniform dose distribution in the target volume. In order to create a SOBP, several Bragg peaks of different ranges, corresponding to different entrance energies, with certain intensities (weights) should be combined each other. In a passive beam scattering system, the beam is usually extracted from a cyclotron at a constant energy throughout a treatment. Therefore, a SOBP is produced by a range modulator wheel, which is basically a rotating wheel with steps of variable thicknesses, or by using the ridge filters. In this study, we used the Geant4 toolkit to simulate a typical passive scattering beam line. In particular, the CATANA transport beam line of INFN Laboratori Nazionali del Sud (LNS) in Catania has been reproduced in this work. Some initial properties of the entrance beam have been checked by benchmarking simulations with experimental data. A class dedicated to the simulation of the wheel modulators has been implemented. It has been designed in order to be easily modified for simulating any desired modulator wheel and, hence, any suitable beam modulation. By using some auxiliary range-shifters, a set of pristine Bragg peaks was obtained from the simulations. A mathematical algorithm was developed, using the simulated pristine dose profiles as its input, to calculate the weight of each pristine peak, reproduce the SOBP, and finally generate a flat dose distribution. Therefore, once the designed modulator has been realized, it has been tested at CATANA facility, comparing the experimental data with the simulation results.

  2. Designing a range modulator wheel to spread-out the Bragg peak for a passive proton therapy facility

    Energy Technology Data Exchange (ETDEWEB)

    Jia, S. Bijan [Physics Department, University of Bojnord, Bojnord (Iran, Islamic Republic of); Romano, F. [INFN, Laboratori Nazionali del Sud, Catania (Italy); Cirrone, Giuseppe A.P. [INFN, Laboratori Nazionali del Sud, Catania (Italy); Institute of Physics of the ASCR, ELI-Beamlines Project, Prague (Czech Republic); Cuttone, G. [INFN, Laboratori Nazionali del Sud, Catania (Italy); Hadizadeh, M.H. [Physics Department, Ferdowsi University of Mashhad, Mashhad (Iran, Islamic Republic of); Mowlavi, A.A. [Physics Department, Hakim Sabzevari University, Sabzevar (Iran, Islamic Republic of); ICTP, Associate Federation Scheme, Medical Physics Field, Trieste (Italy); Raffaele, L. [Azienda Ospedaliero-Universitaria “Policlinico – Vittorio Emanuele”, Catania (Italy)

    2016-01-11

    In proton beam therapy, a Spread-Out Bragg peak (SOBP) is used to establish a uniform dose distribution in the target volume. In order to create a SOBP, several Bragg peaks of different ranges, corresponding to different entrance energies, with certain intensities (weights) should be combined each other. In a passive beam scattering system, the beam is usually extracted from a cyclotron at a constant energy throughout a treatment. Therefore, a SOBP is produced by a range modulator wheel, which is basically a rotating wheel with steps of variable thicknesses, or by using the ridge filters. In this study, we used the Geant4 toolkit to simulate a typical passive scattering beam line. In particular, the CATANA transport beam line of INFN Laboratori Nazionali del Sud (LNS) in Catania has been reproduced in this work. Some initial properties of the entrance beam have been checked by benchmarking simulations with experimental data. A class dedicated to the simulation of the wheel modulators has been implemented. It has been designed in order to be easily modified for simulating any desired modulator wheel and, hence, any suitable beam modulation. By using some auxiliary range-shifters, a set of pristine Bragg peaks was obtained from the simulations. A mathematical algorithm was developed, using the simulated pristine dose profiles as its input, to calculate the weight of each pristine peak, reproduce the SOBP, and finally generate a flat dose distribution. Therefore, once the designed modulator has been realized, it has been tested at CATANA facility, comparing the experimental data with the simulation results.

  3. Beam plug replacement and alignment under high radiation conditions for cold neutron facilities at Hanaro

    International Nuclear Information System (INIS)

    Yeong-Garp, Cho; Jin-Won, Shin; Jung-Hee, Lee; Jeong-Soo, Ryu

    2010-01-01

    Full text : The HANARO, an open-tank-in-pool type research reactor of a 30 MWth power in Korea, has been operating for 15 years since its initial criticality in February 1995. The beam port assigned for the cold neutron at HANARO had been used for an 8-m SANS without neutron guides until it was replaced by a cold neutron guide system in 2008. It was developed a cold neutron guide system for the delivery of cold neutrons from the cold neutron source in the reactor to the neutron scattering instruments in the guide hall. Since the HANARO has been operated from 1995, it was a big challenge to replace the existing plug and shutter with the new facilities under high radiation conditions. When the old plug was removed from the beam port in 2008, the radiation level was 230 mSv/hr at the end of beam port. In addition to that, there were more difficult situations such as the poor as-built dimensions of the beam port, limited work space and time constraint due to other constructions in parallel in the reactor hall. Before the removal of the old plug the level of the radiation was measured coming out through a small hole of the plug to estimate the radiation level during the removal of the old plug and installation of a new plug. Based on the measurement and analysis results, special tools and various shielding facilities were developed for the removal of old in-pile plug and the installation of the new in-pile plug assembly safely. In 2008, the old plug and shutter were successfully replaced by the new plug and shutter as shown in this article with a minimum exposure to the workers. A laser tracker system was also one of the main factors in our successful installation and alignment under high radiation conditions and limited work space. The laser tracker was used to measure and align all the mechanical facilities and the neutron guides with a minimum radiation exposure to workers. The alignment of all the guides and accessories were possible during reactor operation because

  4. Beam dynamics simulations in the photo-cathode RF gun for the CLIC test facility

    International Nuclear Information System (INIS)

    Marchand, P.; Rinolfi, L.

    1992-01-01

    The CERN CLIC Test Facility (CTF) uses an RF gun with a laser driven photo-cathode in order to generate electron pulses of high charge (≥10 nC) and short duration (≤20 ps). The RF gun consists of a 3 GHz 1 + 1/2 cell cavity based on the design originally proposed at BNL which minimizes the non-linearities in the transverse field. The beam dynamics in the cavity is simulated by means of the multiparticle tracking code PARMELA. The results are compared to previous simulations as well as to the first experimental data. (author). 4 refs., 4 tabs., 4 figs

  5. The case for exotic beams at the Holifield Heavy Ion Research Facility

    International Nuclear Information System (INIS)

    Garrett, J.D.

    1991-01-01

    The case is presented for modifying the Holifield Heavy Ion Research Facility at Oak Ridge National Laboratory to provide beams of proton-rich exotic isotopes, that do not occur terrestrially. A program of nuclear structure studies for light- and medium-mass, nearly self-conjugate nuclei and for heavy, proton-rich, quasibound nuclei is outlined, as are studies of hydrogen-burning reactions that occur in nucleosynthetic processes. Such a scientific program will provide a unique future for nuclear physics research at ORNL consistent with the long standing tradition of this laboratory

  6. Selection of targets and ion sources for RIB generation at the Holifield Radioactive Ion Beam Facility

    International Nuclear Information System (INIS)

    Alton, G.D.

    1995-01-01

    In this report, the authors describe the performance characteristics for a selected number of target ion sources that will be employed for initial use at the Holifield Radioactive Ion Beam Facility (HRIBF) as well as prototype ion sources that show promise for future use for RIB applications. A brief review of present efforts to select target materials and to design composite target matrix/heat-sink systems that simultaneously incorporate the short diffusion lengths, high permeabilities, and controllable temperatures required to effect fast and efficient diffusion release of the short-lived species is also given

  7. CEBAF/SURA [Continuous Electron Beam Accelerator Facility]/[Southeastern Universities Research Association] 1988 summer workshop

    International Nuclear Information System (INIS)

    Gross, F.; Lightbody, J.

    1989-01-01

    This report contains papers from a summer workshop of the continuous electron beam accelerator facility. Some topics of these papers are: spectrometers; electron scattering from deuterons; relativistic correlations in nuclear matter; pion production on 3 He and 3 H; quantum electrodynamic processes in crystals; 12 C(e,e'p) x reaction; deuteron polarization tensor and relativistic spin rotation; electromagnetic excitation of nuclei; electron distortion and structure functions in (e,e'p) reactions; and reaction mechanism of 4 He(e,e'p) 3 H

  8. The n_TOF facility: Neutron beams for challenging future measurements at CERN

    Science.gov (United States)

    Chiaveri, E.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bacak, M.; Balibrea, J.; Barbagallo, M.; Bečvář, F.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brown, A.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Cerutti, F.; Chen, Y. H.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Cosentino, L.; Damone, L. A.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Göbel, K.; García, A. R.; Gawlik, A.; Gilardoni, S.; Glodariu, T.; Gonçalves, I. F.; González, E.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Harada, H.; Heinitz, S.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Kalamara, A.; Kavrigin, P.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Kurtulgil, D.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui-Marco, J.; Meo, S. Lo; Lonsdale, S. J.; Macina, D.; Marganiec, J.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Musumarra, A.; Negret, A.; Nolte, R.; Oprea, A.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, I.; Praena, J.; Quesada, J. M.; Radeck, D.; Rauscher, T.; Reifarth, R.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schumann, D.; Smith, A. G.; Sosnin, N. V.; Stamatopoulos, A.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Woods, P. J.; Wright, T.; Žugec, P.

    2017-09-01

    The CERN n_TOF neutron beam facility is characterized by a very high instantaneous neutron flux, excellent TOF resolution at the 185 m long flight path (EAR-1), low intrinsic background and coverage of a wide range of neutron energies, from thermal to a few GeV. These characteristics provide a unique possibility to perform high-accuracy measurements of neutron-induced reaction cross-sections and angular distributions of interest for fundamental and applied Nuclear Physics. Since 2001, the n_TOF Collaboration has collected a wealth of high quality nuclear data relevant for nuclear astrophysics, nuclear reactor technology, nuclear medicine, etc. The overall efficiency of the experimental program and the range of possible measurements has been expanded with the construction of a second experimental area (EAR-2), located 20 m on the vertical of the n_TOF spallation target. This upgrade, which benefits from a neutron flux 30 times higher than in EAR-1, provides a substantial extension in measurement capabilities, opening the possibility to collect data on neutron cross-section of isotopes with short half-lives or available in very small amounts. This contribution will outline the main characteristics of the n_TOF facility, with special emphasis on the new experimental area. In particular, we will discuss the innovative features of the EAR-2 neutron beam that make possible to perform very challenging measurements on short-lived radioisotopes or sub-mg samples, out of reach up to now at other neutron facilities around the world. Finally, the future perspectives of the facility will be presented.

  9. Dosimetric properties of the fast neutron therapy beams at TAMVEC

    International Nuclear Information System (INIS)

    Almond, P.R.; Smith, A.R.; Smathers, J.R.; Otte, V.A.

    1975-01-01

    In October 1972, M.D. Anderson Hospital and Tumor Institute of the University of Texas System Cancer Center initiated a clinical trial of fast neutron radiotherapy using the cyclotron at Texas A and M University. Initially, the study used neutrons produced by bombarding beryllium with 16 MeV deuterons, but since March, 1973, neutrons from 50 MeV deuterons have been used. The dosimetric properties of the 30 MeV beams have also been measured for comparison with the neutron beams from D-T generators. The three beams are compared in terms of dose rate, skin sparing, depth dose and field flatness. Isodose curves for treatment planning were generated using the decrement line method and compared to curves measured by a computer controlled isodose plotter. This system was also used to measure the isodose curves for wedge fields. Dosimetry checks on various patients were made using silicon diodes as in vivo fast neutron dosimeters

  10. Generating AN Optimum Treatment Plan for External Beam Radiation Therapy.

    Science.gov (United States)

    Kabus, Irwin

    1990-01-01

    The application of linear programming to the generation of an optimum external beam radiation treatment plan is investigated. MPSX, an IBM linear programming software package was used. All data originated from the CAT scan of an actual patient who was treated for a pancreatic malignant tumor before this study began. An examination of several alternatives for representing the cross section of the patient showed that it was sufficient to use a set of strategically placed points in the vital organs and tumor and a grid of points spaced about one half inch apart for the healthy tissue. Optimum treatment plans were generated from objective functions representing various treatment philosophies. The optimum plans were based on allowing for 216 external radiation beams which accounted for wedges of any size. A beam reduction scheme then reduced the number of beams in the optimum plan to a number of beams small enough for implementation. Regardless of the objective function, the linear programming treatment plan preserved about 95% of the patient's right kidney vs. 59% for the plan the hospital actually administered to the patient. The clinician, on the case, found most of the linear programming treatment plans to be superior to the hospital plan. An investigation was made, using parametric linear programming, concerning any possible benefits derived from generating treatment plans based on objective functions made up of convex combinations of two objective functions, however, this proved to have only limited value. This study also found, through dual variable analysis, that there was no benefit gained from relaxing some of the constraints on the healthy regions of the anatomy. This conclusion was supported by the clinician. Finally several schemes were found that, under certain conditions, can further reduce the number of beams in the final linear programming treatment plan.

  11. Beam Test for Evaluating Applicabillity of High - Strength Reinforcement in Structure of Nuclear Facility

    International Nuclear Information System (INIS)

    Yim, Sangjun; Lee, Byungsoo; Bang, Changjoon

    2014-01-01

    The high-strength rebar which has high yield strength can reduce the amount of rebar in concrete and widen its spacing so that it has better workability and higher economic benefits for the structure. However, the maximum yield strength of rebar is limited to 420MPa in the design criteria for structure of nuclear facility in Korea and USA. Korea Hydro and Nuclear Power is progressing research to revise the limitation in the yield strength of rebar, which is suggested in the criteria of KEPIC and ACI, in order to apply 550 MPa high-strength rebar for the construction of a nuclear facility. This study is to review the applicability of high strength rebar in structure of a nuclear facility through a model beam test. After reviewing the shear capacity and reinforcement yield to assess the applicability of high-strength reinforcement in the structure of a nuclear facility, we make the following conclusions. When using high shear reinforcement with wider spacing, it has a similar shear capacity to normal reinforcement with narrower spacing. This means better workability and economic benefits can be achieved by widening the rebar spacing without brittle fracture in the elements. For future plans, the results of this test and supplementary test will be submitted to ACI349 committee as backup data to revise the standard for yield strength of high-strength rebar

  12. Beam Test for Evaluating Applicabillity of High - Strength Reinforcement in Structure of Nuclear Facility

    Energy Technology Data Exchange (ETDEWEB)

    Yim, Sangjun; Lee, Byungsoo; Bang, Changjoon [Korea Hydro and Nuclear Power Co., Ltd., Daejeon (Korea, Republic of)

    2014-05-15

    The high-strength rebar which has high yield strength can reduce the amount of rebar in concrete and widen its spacing so that it has better workability and higher economic benefits for the structure. However, the maximum yield strength of rebar is limited to 420MPa in the design criteria for structure of nuclear facility in Korea and USA. Korea Hydro and Nuclear Power is progressing research to revise the limitation in the yield strength of rebar, which is suggested in the criteria of KEPIC and ACI, in order to apply 550 MPa high-strength rebar for the construction of a nuclear facility. This study is to review the applicability of high strength rebar in structure of a nuclear facility through a model beam test. After reviewing the shear capacity and reinforcement yield to assess the applicability of high-strength reinforcement in the structure of a nuclear facility, we make the following conclusions. When using high shear reinforcement with wider spacing, it has a similar shear capacity to normal reinforcement with narrower spacing. This means better workability and economic benefits can be achieved by widening the rebar spacing without brittle fracture in the elements. For future plans, the results of this test and supplementary test will be submitted to ACI349 committee as backup data to revise the standard for yield strength of high-strength rebar.

  13. International Scoping Study (ISS) for a future neutrino factory and Super-Beam facility. Detectors and flux instrumentation for future neutrino facilities

    International Nuclear Information System (INIS)

    Abe, T; Aihara, H; Andreopoulos, C; Ankowski, A; Badertscher, A; Battistoni, G; Blondel, A; Bouchez, J; Bross, A; Ellis, M; Bueno, A; Camilleri, L; Campagne, J E; Cazes, A; Cervera-Villanueva, A; De Lellis, G; Di Capua, F; Ereditato, A; Esposito, L S

    2009-01-01

    This report summarises the conclusions from the detector group of the International Scoping Study of a future Neutrino Factory and Super-Beam neutrino facility. The baseline detector options for each possible neutrino beam are defined as follows: 1. A very massive (Megaton) water Cherenkov detector is the baseline option for a sub-GeV Beta Beam and Super Beam facility. 2. There are a number of possibilities for either a Beta Beam or Super Beam (SB) medium energy facility between 1-5 GeV. These include a totally active scintillating detector (TASD), a liquid argon TPC or a water Cherenkov detector. 3. A 100 kton magnetized iron neutrino detector (MIND) is the baseline to detect the wrong sign muon final states (golden channel) at a high energy (20-50 GeV) neutrino factory from muon decay. A 10 kton hybrid neutrino magnetic emulsion cloud chamber detector for wrong sign tau detection (silver channel) is a possible complement to MIND, if one needs to resolve degeneracies that appear in the δ-θ 13 parameter space.

  14. The Holifield Radioactive Ion Beam Facility at the Oak Ridge National Laboratory: Present status and future plans

    International Nuclear Information System (INIS)

    Alton, G.D.; Beene, J.R.

    1998-01-01

    The Holifield Radioactive Ion Beam Facility (HRIBF) is a first generation national user facility for nuclear physics and nuclear astrophysics research with radioactive ion beams (RIBs). The reconfiguration, construction, and equipment commissioning phases have been completed and the beam development program is in progress. In this article, descriptions of the facility and newly implemented experimental equipment for use in the nuclear and astrophysics programs will be given and an outline of the initial experimental program will be presented. Special target ion source related problems, endemic to the production of specific short lived RIBs will be discussed. In addition, plans, which involve either a 200 MeV or a 1 GeV proton linac driver for a second generation ISOL facility, will be presented

  15. SU-D-BRC-01: An Automatic Beam Model Commissioning Method for Monte Carlo Simulations in Pencil-Beam Scanning Proton Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Qin, N; Shen, C; Tian, Z; Jiang, S; Jia, X [UT Southwestern Medical Ctr, Dallas, TX (United States)

    2016-06-15

    Purpose: Monte Carlo (MC) simulation is typically regarded as the most accurate dose calculation method for proton therapy. Yet for real clinical cases, the overall accuracy also depends on that of the MC beam model. Commissioning a beam model to faithfully represent a real beam requires finely tuning a set of model parameters, which could be tedious given the large number of pencil beams to commmission. This abstract reports an automatic beam-model commissioning method for pencil-beam scanning proton therapy via an optimization approach. Methods: We modeled a real pencil beam with energy and spatial spread following Gaussian distributions. Mean energy, and energy and spatial spread are model parameters. To commission against a real beam, we first performed MC simulations to calculate dose distributions of a set of ideal (monoenergetic, zero-size) pencil beams. Dose distribution for a real pencil beam is hence linear superposition of doses for those ideal pencil beams with weights in the Gaussian form. We formulated the commissioning task as an optimization problem, such that the calculated central axis depth dose and lateral profiles at several depths match corresponding measurements. An iterative algorithm combining conjugate gradient method and parameter fitting was employed to solve the optimization problem. We validated our method in simulation studies. Results: We calculated dose distributions for three real pencil beams with nominal energies 83, 147 and 199 MeV using realistic beam parameters. These data were regarded as measurements and used for commission. After commissioning, average difference in energy and beam spread between determined values and ground truth were 4.6% and 0.2%. With the commissioned model, we recomputed dose. Mean dose differences from measurements were 0.64%, 0.20% and 0.25%. Conclusion: The developed automatic MC beam-model commissioning method for pencil-beam scanning proton therapy can determine beam model parameters with

  16. Quantitative evaluation of potential irradiation geometries for carbon-ion beam grid therapy.

    Science.gov (United States)

    Tsubouchi, Toshiro; Henry, Thomas; Ureba, Ana; Valdman, Alexander; Bassler, Niels; Siegbahn, Albert

    2018-03-01

    Radiotherapy using grids containing cm-wide beam elements has been carried out sporadically for more than a century. During the past two decades, preclinical research on radiotherapy with grids containing small beam elements, 25 μm-0.7 mm wide, has been performed. Grid therapy with larger beam elements is technically easier to implement, but the normal tissue tolerance to the treatment is decreasing. In this work, a new approach in grid therapy, based on irradiations with grids containing narrow carbon-ion beam elements was evaluated dosimetrically. The aim formulated for the suggested treatment was to obtain a uniform target dose combined with well-defined grids in the irradiated normal tissue. The gain, obtained by crossfiring the carbon-ion beam grids over a simulated target volume, was quantitatively evaluated. The dose distributions produced by narrow rectangular carbon-ion beams in a water phantom were simulated with the PHITS Monte Carlo code. The beam-element height was set to 2.0 cm in the simulations, while the widths varied from 0.5 to 10.0 mm. A spread-out Bragg peak (SOBP) was then created for each beam element in the grid, to cover the target volume with dose in the depth direction. The dose distributions produced by the beam-grid irradiations were thereafter constructed by adding the dose profiles simulated for single beam elements. The variation of the valley-to-peak dose ratio (VPDR) with depth in water was thereafter evaluated. The separation of the beam elements inside the grids were determined for different irradiation geometries with a selection criterion. The simulated carbon-ion beams remained narrow down to the depths of the Bragg peaks. With the formulated selection criterion, a beam-element separation which was close to the beam-element width was found optimal for grids containing 3.0-mm-wide beam elements, while a separation which was considerably larger than the beam-element width was found advantageous for grids containing 0.5-mm

  17. Real-time beam monitoring in scanned proton therapy

    Science.gov (United States)

    Klimpki, G.; Eichin, M.; Bula, C.; Rechsteiner, U.; Psoroulas, S.; Weber, D. C.; Lomax, A.; Meer, D.

    2018-05-01

    When treating cancerous tissues with protons beams, many centers make use of a step-and-shoot irradiation technique, in which the beam is steered to discrete grid points in the tumor volume. For safety reasons, the irradiation is supervised by an independent monitoring system validating cyclically that the correct amount of protons has been delivered to the correct position in the patient. Whenever unacceptable inaccuracies are detected, the irradiation can be interrupted to reinforce a high degree of radiation protection. At the Paul Scherrer Institute, we plan to irradiate tumors continuously. By giving up the idea of discrete grid points, we aim to be faster and more flexible in the irradiation. But the increase in speed and dynamics necessitates a highly responsive monitoring system to guarantee the same level of patient safety as for conventional step-and-shoot irradiations. Hence, we developed and implemented real-time monitoring of the proton beam current and position. As such, we read out diagnostic devices with 100 kHz and compare their signals against safety tolerances in an FPGA. In this paper, we report on necessary software and firmware enhancements of our control system and test their functionality based on three exemplary error scenarios. We demonstrate successful implementation of real-time beam monitoring and, consequently, compliance with international patient safety regulations.

  18. Moving beam irradiation in combined therapy of cervix uteri cancer

    Energy Technology Data Exchange (ETDEWEB)

    Kim, O M; Zholkiver, K I

    1976-07-01

    Postoperative moving beam irradiation in a dose of 3900 to 365 rad was conducted in 98 patients with the I--II stages of cervix uteri cancer. Skin reactions to irradiation were absent, marked leukopenia developed in 4 patients. Of 39 patients followed up for more than 5 years 35 have lived without relapses and metastases.

  19. T2-weighted endorectal magnetic resonance imaging of prostate cancer after external beam radiation therapy

    International Nuclear Information System (INIS)

    Westphalen, Antonio C.; Kurhanewicz, John; Cunha, Rui M.G.; Hsu, I-Chow; Kornak, John; Zhao, Shoujun; Coakley, Fergus V.

    2009-01-01

    Purpose: To retrospectively determine the accuracy of T2-weighted endorectal MR imaging in the detection of prostate cancer after external beam radiation therapy and to investigate the relationship between imaging accuracy and time since therapy. Materials and Methods: Institutional review board approval was obtained and the study was HIPPA compliant. We identified 59 patients who underwent 1.5 Tesla endorectal MR imaging of the prostate between 1999 and 2006 after definitive external beam radiation therapy for biopsy-proven prostate cancer. Two readers recorded the presence or absence of tumor on T2-weighted images. Logistic regression and Fisher's exact tests for 2x2 tables were used to determine the accuracy of imaging and investigate if accuracy differed between those imaged within 3 years of therapy (n = 25) and those imaged more than 3 years after therapy (n = 34). Transrectal biopsy was used as the standard of reference for the presence or absence of recurrent cancer. Results: Thirty-four of 59 patients (58%) had recurrent prostate cancer detected on biopsy. The overall accuracy of T2-weighted MR imaging in the detection cancer after external beam radiation therapy was 63% (37/59) for reader 1 and 71% for reader 2 (42/59). For both readers, logistic regression showed no difference in accuracy between those imaged within 3 years of therapy and those imaged more than 3 years after therapy (p = 0.86 for reader 1 and 0.44 for reader 2). Conclusion: T2-weighted endorectal MR imaging has low accuracy in the detection of prostate cancer after external beam radiation therapy, irrespective of the time since therapy. (author)

  20. IEEE 1394 CAMERA IMAGING SYSTEM FOR BROOKHAVENS BOOSTER APPLICATION FACILITY BEAM DIAGNOSTICS

    International Nuclear Information System (INIS)

    BROWN, K.A.; FRAK, B.; GASSNER, D.; HOFF, L.; OLSEN, R.H.; SATOGATA, T.; TEPIKIAN, S.

    2002-01-01

    Brookhaven's Booster Applications Facility (BAF) will deliver resonant extracted heavy ion beams from the AGS Booster to short-exposure fixed-target experiments located at the end of the BAF beam line. The facility is designed to deliver a wide range of heavy ion species over a range of intensities from 10 3 to over 10 8 ions/pulse, and over a range of energies from 0.1 to 3.0 GeV/nucleon. With these constraints we have designed instrumentation packages which can deliver the maximum amount of dynamic range at a reasonable cost. Through the use of high quality optics systems and neutral density light filters we will achieve 4 to 5 orders of magnitude in light collection. By using digital IEEE1394 camera systems we are able to eliminate the frame-grabber stage in processing and directly transfer data at maximum rates of 400 Mb/set. In this note we give a detailed description of the system design and discuss the parameters used to develop the system specifications. We will also discuss the IEEE1394 camera software interface and the high-level user interface

  1. Proton therapy posterior beam approach with pencil beam scanning for esophageal cancer. Clinical outcome, dosimetry, and feasibility

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Yue-Can [Shengjing Hospital of China Medical University, Department of Medical Oncology, Cancer Center, Shenyang (China); University of Washington Medical Center, Department of Radiation Oncology, 1959 NE Pacific Street, Campus Box 356043, Seattle, WA (United States); Vyas, Shilpa; Apisarnthanarax, Smith; Zeng, Jing [University of Washington Medical Center, Department of Radiation Oncology, 1959 NE Pacific Street, Campus Box 356043, Seattle, WA (United States); Dang, Quang; Schultz, Lindsay [Seattle Cancer Care Alliance Proton Therapy Center, Seattle, WA (United States); Bowen, Stephen R. [University of Washington Medical Center, Department of Radiation Oncology, 1959 NE Pacific Street, Campus Box 356043, Seattle, WA (United States); University of Washington Medical Center, Department of Radiology, Seattle, WA (United States); Shankaran, Veena [University of Washington Medical Center, Department of Medical Oncology, Seattle, WA (United States); Farjah, Farhood [University of Washington Medical Center, Department of Surgery, Division of Cardiothoracic Surgery, Seattle, WA (United States); University of Washington Medical Center, Department of Surgery, Surgical Outcomes Research Center, Seattle, WA (United States); Oelschlager, Brant K. [University of Washington Medical Center, Department of Surgery, Seattle, WA (United States)

    2016-12-15

    The aim of this study is to present the dosimetry, feasibility, and preliminary clinical results of a novel pencil beam scanning (PBS) posterior beam technique of proton treatment for esophageal cancer in the setting of trimodality therapy. From February 2014 to June 2015, 13 patients with locally advanced esophageal cancer (T3-4N0-2M0; 11 adenocarcinoma, 2 squamous cell carcinoma) were treated with trimodality therapy (neoadjuvant chemoradiation followed by esophagectomy). Eight patients were treated with uniform scanning (US) and 5 patients were treated with a single posterior-anterior (PA) beam PBS technique with volumetric rescanning for motion mitigation. Comparison planning with PBS was performed using three plans: AP/PA beam arrangement; PA plus left posterior oblique (LPO) beams, and a single PA beam. Patient outcomes, including pathologic response and toxicity, were evaluated. All 13 patients completed chemoradiation to 50.4 Gy (relative biological effectiveness, RBE) and 12 patients underwent surgery. All 12 surgical patients had an R0 resection and pathologic complete response was seen in 25 %. Compared with AP/PA plans, PA plans have a lower mean heart (14.10 vs. 24.49 Gy, P < 0.01), mean stomach (22.95 vs. 31.33 Gy, P = 0.038), and mean liver dose (3.79 vs. 5.75 Gy, P = 0.004). Compared to the PA/LPO plan, the PA plan reduced the lung dose: mean lung dose (4.96 vs. 7.15 Gy, P = 0.020) and percentage volume of lung receiving 20 Gy (V{sub 20}; 10 vs. 17 %, P < 0.01). Proton therapy with a single PA beam PBS technique for preoperative treatment of esophageal cancer appears safe and feasible. (orig.) [German] Wir stellen die Vergleichsdosimetrie, Realisierbarkeit und die vorlaeufigen klinischen Ergebnisse einer neuen Pencil-Beam-Scanning(-PBS)/Posterior-Beam-Methode innerhalb der Protonentherapie fuer Speiseroehrenkrebs im Setting einer trimodalen Therapie vor. Von Februar 2014 bis Juni 2015 erhielten 13 Patienten mit lokal fortgeschrittenem

  2. A 4 MV flattening filter-free beam: commissioning and application to conformal therapy and volumetric modulated arc therapy

    International Nuclear Information System (INIS)

    Stevens, S W; Rosser, K E; Bedford, J L

    2011-01-01

    Recent studies have indicated that radiotherapy treatments undertaken on a flattening filter-free (FFF) linear accelerator have a number of advantages over treatments undertaken on a conventional linear accelerator. In addition, 4 MV photon beams may give improved isodose coverage for some treatment volumes at air/tissue interfaces, compared to when utilizing the clinical standard of 6 MV photons. In order to investigate these benefits, FFF beams were established on an Elekta Beam Modulator linear accelerator for 4 MV photons. Commissioning beam data were obtained for open and wedged fields. The measured data were then imported into a treatment planning system and a beam model was commissioned. The beam model was optimized to improve dose calculations at shallow, clinically relevant depths. Following verification, the beam model was utilized in a treatment planning study, including volumetric modulated arc therapy, for a selection of lung, breast/chest wall and larynx patients. Increased dose rates of around 800 MU min -1 were recorded for open fields (relative to 320 MU min -1 for filtered open fields) and reduced head scatter was inferred from output factor measurements. Good agreement between planned and delivered dose was observed in verification of treatment plans. The planning study indicated that with a FFF beam, equivalent (and in some cases improved) isodose profiles could be achieved for small lung and larynx treatment volumes relative to 4 MV filtered treatments. Furthermore, FFF treatments with wedges could be replicated using open fields together with an 'effective wedge' technique and isocentre shift. Clinical feasibility of a FFF beam was therefore demonstrated, with beam modelling, treatment planning and verification being successfully accomplished.

  3. Targets for ion sources for RIB generation at the Holifield Radioactive Ion Beam Facility

    International Nuclear Information System (INIS)

    Alton, G.D.

    1995-01-01

    The Holifield Radioactive Ion Beam Facility (HRIBF), now under construction at the Oak Ridge National Laboratory, is based on the use of the well-known on-line isotope separator (ISOL) technique in which radioactive nuclei are produced by fusion type reactions in selectively chosen target materials by high-energy proton, deuteron, or He ion beams from the Oak Ridge Isochronous Cyclotron (ORIC). Among several major challenges posed by generating and accelerating adequate intensities of radioactive ion beams (RIBs), selection of the most appropriate target material for production of the species of interest is, perhaps, the most difficult. In this report, we briefly review present efforts to select target materials and to design composite target matrix/heat-sink systems that simultaneously incorporate the short diffusion lengths, high permeabilities, and controllable temperatures required to effect maximum diffusion release rates of the short-lived species that can be realized at the temperature limits of specific target materials. We also describe the performance characteristics for a selected number of target ion sources that will be employed for initial use at the HRIBF as well as prototype ion sources that show promise for future use for RIB applications

  4. THE PRIMARY TARGET FACILITY FOR A NEUTRINO FACTORY BASED ON MUON BEAMS

    International Nuclear Information System (INIS)

    HASSENEIN, A.; KAHN, S.A.; KING, B.J.; KIRK, H.G.; LUDEWIG, H.; PALMER, R.B.; PEARSON, C.E.; SAMULYAK, R.; SIMOS, N.; STUMER, I.; THIEBERGER, P.; WEGGEL, R.J.

    2001-01-01

    Neutrino beams from the decay of muons in a storage ring offer the prospect of very high flux, well-understood spectra, and equal numbers of electron and muon neutrinos, as desirable for detailed exploration of neutrino oscillations via long baseline detectors [1]. Such beams require. large numbers of muons, and hence a high performance target station at which a 1-4 MW proton beam of 16-24 GeV impinges on a compact target, all inside a high field solenoid channel to capture as much of the phase volume of soft pions as possible. A first concept was based on a carbon target, as reported in 2000 the Neutrino Factory Study-I [2]. A higher performance option based on a free mercury jet has been studied in 2001 as part of the Neutrino Factory Feasibility Study-II [3,4]. An overview of a mercury jet target facility is presented here, including requirements, design concept and summaries of simulated performance. Further details are presented in related papers at this conference

  5. The PRIMA Test Facility: SPIDER and MITICA test-beds for ITER neutral beam injectors

    Science.gov (United States)

    Toigo, V.; Piovan, R.; Dal Bello, S.; Gaio, E.; Luchetta, A.; Pasqualotto, R.; Zaccaria, P.; Bigi, M.; Chitarin, G.; Marcuzzi, D.; Pomaro, N.; Serianni, G.; Agostinetti, P.; Agostini, M.; Antoni, V.; Aprile, D.; Baltador, C.; Barbisan, M.; Battistella, M.; Boldrin, M.; Brombin, M.; Dalla Palma, M.; De Lorenzi, A.; Delogu, R.; De Muri, M.; Fellin, F.; Ferro, A.; Fiorentin, A.; Gambetta, G.; Gnesotto, F.; Grando, L.; Jain, P.; Maistrello, A.; Manduchi, G.; Marconato, N.; Moresco, M.; Ocello, E.; Pavei, M.; Peruzzo, S.; Pilan, N.; Pimazzoni, A.; Recchia, M.; Rizzolo, A.; Rostagni, G.; Sartori, E.; Siragusa, M.; Sonato, P.; Sottocornola, A.; Spada, E.; Spagnolo, S.; Spolaore, M.; Taliercio, C.; Valente, M.; Veltri, P.; Zamengo, A.; Zaniol, B.; Zanotto, L.; Zaupa, M.; Boilson, D.; Graceffa, J.; Svensson, L.; Schunke, B.; Decamps, H.; Urbani, M.; Kushwah, M.; Chareyre, J.; Singh, M.; Bonicelli, T.; Agarici, G.; Garbuglia, A.; Masiello, A.; Paolucci, F.; Simon, M.; Bailly-Maitre, L.; Bragulat, E.; Gomez, G.; Gutierrez, D.; Mico, G.; Moreno, J.-F.; Pilard, V.; Kashiwagi, M.; Hanada, M.; Tobari, H.; Watanabe, K.; Maejima, T.; Kojima, A.; Umeda, N.; Yamanaka, H.; Chakraborty, A.; Baruah, U.; Rotti, C.; Patel, H.; Nagaraju, M. V.; Singh, N. P.; Patel, A.; Dhola, H.; Raval, B.; Fantz, U.; Heinemann, B.; Kraus, W.; Hanke, S.; Hauer, V.; Ochoa, S.; Blatchford, P.; Chuilon, B.; Xue, Y.; De Esch, H. P. L.; Hemsworth, R.; Croci, G.; Gorini, G.; Rebai, M.; Muraro, A.; Tardocchi