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Sample records for beam breast x-ray

  1. Hard X-ray Microscopic Imaging Of Human Breast Tissues

    Science.gov (United States)

    Park, Sung H.; Kim, Hong T.; Kim, Jong K.; Jheon, Sang H.; Youn, Hwa S.

    2007-01-01

    X-ray microscopy with synchrotron radiation will be a useful tool for innovation of x-ray imaging in clinical and laboratory settings. It helps us observe detailed internal structure of material samples non-invasively in air. And, it also has the potential to solve some tough problems of conventional breast imaging if it could evaluate various conditions of breast tissue effectively. A new hard x-ray microscope with a spatial resolution better than 100 nm was installed at Pohang Light Source, a third generation synchrotron radiation facility in Pohang, Korea. The x-ray energy was set at 6.95 keV, and the x-ray beam was monochromatized by W/B4C monochromator. Condenser and objective zone plates were used as x-ray lenses. Zernike phase plate next to condenser zone plate was introduced for improved contrast imaging. The image of a sample was magnified 30 times by objective zone plate and 20 times by microscope objective, respectively. After additional 10 times digital magnification, the total magnifying power was up to 6000 times in the end. Phase contrast synchrotron images of 10-μm-thick female breast tissue of the normal, fibroadenoma, fibrocystic change and carcinoma cases were obtained. By phase contrast imaging, hard x-rays enable us to observe many structures of breast tissue without sample preparations such as staining or fixation.

  2. Hard X-ray Microscopic Imaging Of Human Breast Tissues

    International Nuclear Information System (INIS)

    Park, Sung H.; Kim, Hong T.; Kim, Jong K.; Jheon, Sang H.; Youn, Hwa S.

    2007-01-01

    X-ray microscopy with synchrotron radiation will be a useful tool for innovation of x-ray imaging in clinical and laboratory settings. It helps us observe detailed internal structure of material samples non-invasively in air. And, it also has the potential to solve some tough problems of conventional breast imaging if it could evaluate various conditions of breast tissue effectively. A new hard x-ray microscope with a spatial resolution better than 100 nm was installed at Pohang Light Source, a third generation synchrotron radiation facility in Pohang, Korea. The x-ray energy was set at 6.95 keV, and the x-ray beam was monochromatized by W/B4C monochromator. Condenser and objective zone plates were used as x-ray lenses. Zernike phase plate next to condenser zone plate was introduced for improved contrast imaging. The image of a sample was magnified 30 times by objective zone plate and 20 times by microscope objective, respectively. After additional 10 times digital magnification, the total magnifying power was up to 6000 times in the end. Phase contrast synchrotron images of 10-μm-thick female breast tissue of the normal, fibroadenoma, fibrocystic change and carcinoma cases were obtained. By phase contrast imaging, hard x-rays enable us to observe many structures of breast tissue without sample preparations such as staining or fixation

  3. X-ray beam generator

    International Nuclear Information System (INIS)

    Koller, T.J.; Randmer, J.A.

    1977-01-01

    A method of minimizing the preferential angular absorption of the divergent beam from an X-ray generator is described. The generator consists of an X-ray shielded housing with an X-ray transmissive window symmetrically placed in radial alignment with a focal spot area on a sloped target surface of an X-ray tube in the housing. The X-ray tube may be of the stationary anode type or of the rotating anode type. (U.K.)

  4. Application of small-angle X-ray scattering for differentiation among breast tumors

    International Nuclear Information System (INIS)

    Changizi, V.; Kheradmand, A. Arab; Oghabian, M.A.

    2008-01-01

    Small-angle X-ray scattering (SAXS) is an X-ray diffraction-based technique where a narrow collimated beam of X-rays is focused onto a sample and the scattered X-rays recorded by a detector. The pattern of the scattered X-rays carries information on the molecular structure of the material. As breast cancer is the most widespread cancer in women and differentiation among its tumors is important, this project compared the results of coherent X-ray scattering measurements obtained from benign and malignant breast tissues. The energy-dispersive method with a setup including X-ray tube, primary collimator, sample holder, secondary collimator and high-purity germanium (HpGe) detector was used. One hundred thirty-one breast-tissue samples, including normal, fibrocystic changes and carcinoma, were studied at the 6 deg scattering angle. Diffraction profiles (corrected scattered intensity versus momentum transfer) of normal, fibrocystic changes and carcinoma were obtained. These profiles showed a few peak positions for adipose (1.15 ± 0.06 nm -1 ), mixed normal (1.15 ± 0.06 nm -1 and 1.4 ± 0.04 nm -1 ), fibrocystic changes (1.46 ± 0.05 nm -1 and 1.74 ± 0.04 nm -1 ) and carcinoma (1.55 ± 0.04 nm -1 , 1.73 ± 0.06 nm -1 , 1.85 ± 0.05 nm -1 ). We were able to differentiate between normal, fibrocystic changes (benign) and carcinoma (malignant) breast tissues by SAXS. However, we were unable to differentiate between different types of carcinoma. (author)

  5. Application of small-angle X-ray scattering for differentiation among breast tumors

    Directory of Open Access Journals (Sweden)

    Changizi V

    2008-01-01

    Full Text Available Small-angle X-ray scattering (SAXS is an X-ray diffraction-based technique where a narrow collimated beam of X-rays is focused onto a sample and the scattered X-rays recorded by a detector. The pattern of the scattered X-rays carries information on the molecular structure of the material. As breast cancer is the most widespread cancer in women and differentiation among its tumors is important, this project compared the results of coherent X-ray scattering measurements obtained from benign and malignant breast tissues. The energy-dispersive method with a setup including X-ray tube, primary collimator, sample holder, secondary collimator and high-purity germanium (HpGe detector was used. One hundred thirty-one breast-tissue samples, including normal, fibrocystic changes and carcinoma, were studied at the 6° scattering angle. Diffraction profiles (corrected scattered intensity versus momentum transfer of normal, fibrocystic changes and carcinoma were obtained. These profiles showed a few peak positions for adipose (1.15 ± 0.06 nm -1 , mixed normal (1.15 ± 0.06 nm -1 and 1.4 ± 0.04 nm -1 , fibrocystic changes (1.46 ± 0.05 nm -1 and 1.74 ± 0.04 nm -1 and carcinoma (1.55 ± 0.04 nm -1 , 1.73 ± 0.06 nm -1 , 1.85 ± 0.05 nm -1 . We were able to differentiate between normal, fibrocystic changes (benign and carcinoma (malignant breast tissues by SAXS. However, we were unable to differentiate between different types of carcinoma.

  6. Cone-beam volume CT breast imaging: Feasibility study

    International Nuclear Information System (INIS)

    Chen Biao; Ning Ruola

    2002-01-01

    X-ray projection mammography, using a film/screen combination, or digital techniques, has proven to be the most effective imaging modality currently available for early detection of breast cancer. However, the inherent superimposition of structures makes a small carcinoma (a few millimeters in size) difficult to detect when it is occult or in dense breasts, leading to a high false-positive biopsy rate. Cone-beam x-ray-projection-based volume imaging using flat panel detectors (FPDs) may allow obtaining three-dimensional breast images, resulting in more accurate diagnosis of structures and patterns of lesions while eliminating the hard compression of breasts. This article presents a novel cone-beam volume computed tomographic breast imaging (CBVCTBI) technique based on the above techniques. Through a variety of computer simulations, the key issues of the system and imaging techniques were addressed, including the x-ray imaging geometry and corresponding reconstruction algorithms, x-ray characteristics of breast tissue and lesions, x-ray setting techniques, the absorbed dose estimation, and the quantitative effect of x-ray scattering on image quality. The preliminary simulation results support the proposed CVBCTBI modality for breast imaging in respect to its feasibility and practicability. The absorbed dose level is comparable to that of current mammography and will not be a prominent problem for this imaging technique. Compared to conventional mammography, the proposed imaging technique with isotropic spatial resolution will potentially provide significantly better low-contrast detectability of breast tumors and more accurate location of breast lesions

  7. Determination of x-ray spectra incident on and transmitted through whole excised breast for improved mammographic exposing technique

    International Nuclear Information System (INIS)

    Haus, A.G.; Metz, C.E.; Doi, K.; Bernstein, J.

    1976-01-01

    Measurements were made of x-ray spectra incident on and transmitted through whole excised fresh breast tissue. The spectra and corresponding radiographs show that hardening of the x-ray beam from a molybdenum anode x-ray tube by a 0.5 mm Al filter instead of the conventional 0.03 mm Mo filter allows shorter exposure times and reduces patient radiation exposure. With the Al filter, acceptable image contrast is preserved in mammography of thick or dense breasts

  8. Effect of area x-ray beam equalization on image quality and dose in digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Jerry; Xu Tong; Husain, Adeel; Le, Huy; Molloi, Sabee [Department of Radiological Sciences, University of California, Irvine, CA 92697 (United States)

    2004-08-21

    In mammography, thick or dense breast regions persistently suffer from reduced contrast-to-noise ratio (CNR) because of degraded contrast from large scatter intensities and relatively high noise. Area x-ray beam equalization can improve image quality by increasing the x-ray exposure to under-penetrated regions without increasing the exposure to other breast regions. Optimal equalization parameters with respect to image quality and patient dose were determined through computer simulations and validated with experimental observations on a step phantom and an anthropomorphic breast phantom. Three parameters important in equalization digital mammography were considered: attenuator material (Z = 13-92), beam energy (22-34 kVp) and equalization level. A Mo/Mo digital mammography system was used for image acquisition. A prototype 16 x 16 piston driven equalization system was used for preparing patient-specific equalization masks. Simulation studies showed that a molybdenum attenuator and an equalization level of 20 were optimal for improving contrast, CNR and figure of merit (FOM = CNR{sup 2}/dose). Experimental measurements using these parameters showed significant improvements in contrast, CNR and FOM. Moreover, equalized images of a breast phantom showed improved image quality. These results indicate that area beam equalization can improve image quality in digital mammography.

  9. X-ray examination for breast cancer: Benefit versus risk

    International Nuclear Information System (INIS)

    Dalrymple, G.V.; Baker, M.L.

    1984-01-01

    Cancer of the breast is the most common malignancy afflicting American women. According to the American Cancer Society, one of 11 women (9 percent) born in the United States today, will develop breast cancer in her lifetime. Twenty-seven percent of all cancers in women and 19 percent of all cancer deaths in women are attributable to breast cancer. In 1982, 112,000 women were found to have cancer of the breast, and 37,000 women died from breast cancer. X-ray examinations of the breast are of considerable value in the diagnosis of breast cancer. This may be especially true in the asymptomatic patient who does not have a palpable mass. These x-ray examinations, however, are associated with both a finite though small risk of induction of cancer of the breasts and even smaller risk of death from cancer of the breast. This chapter presents a brief review of cancer of the breast and discusses the value of diagnostic studies, including x-ray mammography; the benefits and risks associated with x-ray examinations; and the future potential of computed tomography (CT) and ultrasound as imaging modalities in the detection of breast cancer

  10. Advances in kilovoltage x-ray beam dosimetry

    Science.gov (United States)

    Hill, Robin; Healy, Brendan; Holloway, Lois; Kuncic, Zdenka; Thwaites, David; Baldock, Clive

    2014-03-01

    This topical review provides an up-to-date overview of the theoretical and practical aspects of therapeutic kilovoltage x-ray beam dosimetry. Kilovoltage x-ray beams have the property that the maximum dose occurs very close to the surface and thus, they are predominantly used in the treatment of skin cancers but also have applications for the treatment of other cancers. In addition, kilovoltage x-ray beams are used in intra operative units, within animal irradiators and in on-board imagers on linear accelerators and kilovoltage dosimetry is important in these applications as well. This review covers both reference and relative dosimetry of kilovoltage x-ray beams and provides recommendations for clinical measurements based on the literature to date. In particular, practical aspects for the selection of dosimeter and phantom material are reviewed to provide suitable advice for medical physicists. An overview is also presented of dosimeters other than ionization chambers which can be used for both relative and in vivo dosimetry. Finally, issues related to the treatment planning and the use of Monte Carlo codes for solving radiation transport problems in kilovoltage x-ray beams are presented.

  11. TU-EF-207-03: Advances in Stationary Breast Tomosynthesis Using Distributed X-Ray Sources

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, O. [The University of North Carolina at Chapel Hill (United States)

    2015-06-15

    mode due to lower photon fluence per projection. This may require fast-frame acquisition and symmetric or asymmetric pixel binning in some systems. Recent studies investigated the performance of increased conversion layer thickness for contrast-enhanced imaging of the breast in dual-energy acquisition mode. In other direct conversion detectors operating in the avalanche mode, sensitivities close to the single photon response are also explored for mammography and breast tomosynthesis. The potential advantages and challenges of this approach are described. Dedicated breast CT brings x-ray imaging of the breast to true tomographic 3D imaging. It can eliminate the tissue superposition problem and does not require physical compression of the breast. Using cone beam geometry and a flat-panel detector, several hundred projections are acquired and reconstructed to near isotropic voxels. Multiplanar reconstruction facilitates viewing the breast volume in any desired orientation. Ongoing clinical studies, the current state-of-the art, and research to advance the technology are described. Learning Objectives: To understand the ongoing developments in x-ray imaging of the breast To understand the approaches and applications of spectral mammography To understand the potential advantages of distributed x-ray source arrays for digital breast tomosynthesis To understand the ongoing developments in detector technology for digital mammography and breast tomosynthesis To understand the current state-of-the-art for dedicated cone-beam breast CT and research to advance the technology. Research collaboration with Koning Corporation.

  12. TU-EF-207-03: Advances in Stationary Breast Tomosynthesis Using Distributed X-Ray Sources

    International Nuclear Information System (INIS)

    Zhou, O.

    2015-01-01

    mode due to lower photon fluence per projection. This may require fast-frame acquisition and symmetric or asymmetric pixel binning in some systems. Recent studies investigated the performance of increased conversion layer thickness for contrast-enhanced imaging of the breast in dual-energy acquisition mode. In other direct conversion detectors operating in the avalanche mode, sensitivities close to the single photon response are also explored for mammography and breast tomosynthesis. The potential advantages and challenges of this approach are described. Dedicated breast CT brings x-ray imaging of the breast to true tomographic 3D imaging. It can eliminate the tissue superposition problem and does not require physical compression of the breast. Using cone beam geometry and a flat-panel detector, several hundred projections are acquired and reconstructed to near isotropic voxels. Multiplanar reconstruction facilitates viewing the breast volume in any desired orientation. Ongoing clinical studies, the current state-of-the art, and research to advance the technology are described. Learning Objectives: To understand the ongoing developments in x-ray imaging of the breast To understand the approaches and applications of spectral mammography To understand the potential advantages of distributed x-ray source arrays for digital breast tomosynthesis To understand the ongoing developments in detector technology for digital mammography and breast tomosynthesis To understand the current state-of-the-art for dedicated cone-beam breast CT and research to advance the technology. Research collaboration with Koning Corporation

  13. Nanoparticle-Assisted Scanning Focusing X-Ray Therapy with Needle Beam X Rays.

    Science.gov (United States)

    Davidson, R Andrew; Guo, Ting

    2016-01-01

    In this work, we show a new therapeutic approach using 40-120 keV X rays to deliver a radiation dose at the isocenter located many centimeters below the skin surface several hundred times greater than at the skin and how this dose enhancement can be augmented with nanomaterials to create several thousand-fold total dose enhancement effect. This novel approach employs a needle X-ray beam directed at the isocenter centimeters deep in the body while continuously scanning the beam to cover a large solid angle without overlapping at the skin. A Monte Carlo method was developed to simulate an X-ray dose delivered to the isocenter filled with X-ray absorbing and catalytic nanoparticles in a water phantom. An experimental apparatus consisting of a moving plastic phantom irradiated with a stationary 1 mm needle X-ray beam was built to test the theoretical predictions. X-ray films were used to characterize the dose profiles of the scanning X-ray apparatus. Through this work, it was determined that the X-ray dose delivered to the isocenter in a treatment voxel (t-voxel) underneath a 5 cm deep high-density polyethylene (HDPE) phantom was 295 ± 48 times greater than the surface dose. This measured value was in good agreement with the theoretical predicted value of 339-fold. Adding X-ray-absorbing nanoparticles, catalytic nanoparticles or both into the t-voxel can further augment the dose enhancement. For example, we predicted that adding 1 weight percentage (wp) of gold into water could increase the effective dose delivered to the target by onefold. Dose enhancement using 1 mm X-ray beam could reach about 1,600-fold in the t-voxel when 7.5 wp of 88 nm diameter silica-covered gold nanoparticles were added, which we showed in a previously published study can create a dose enhancement of 5.5 ± 0.46-fold without scanning focusing enhancement. Based on the experimental data from that study, mixing 0.02 wp 2.5 nm diameter small tetrakis hydroxymethyl phosphonium chloride (THPC

  14. X-ray beam-position feedback system with easy-to-use beam-position monitor.

    Science.gov (United States)

    Park, Jae Yeon; Kim, Yesul; Lee, Sangsul; Lim, Jun

    2018-05-01

    X-ray beam-position stability is indispensable in cutting-edge experiments using synchrotron radiation. Here, for the first time, a beam-position feedback system is presented that utilizes an easy-to-use X-ray beam-position monitor incorporating a diamond-fluorescence screen. The acceptable range of the monitor is above 500 µm and the feedback system maintains the beam position within 3 µm. In addition to being inexpensive, the system has two key advantages: it works without a scale factor for position calibration, and it has no dependence on X-ray energy, X-ray intensity, beam size or beam shape.

  15. Monte Carlo evaluation of glandular dose in cone-beam X-ray computed tomography dedicated to the breast: Homogeneous and heterogeneous breast models.

    Science.gov (United States)

    Sarno, Antonio; Mettivier, Giovanni; Tucciariello, Raffaele M; Bliznakova, Kristina; Boone, John M; Sechopoulos, Ioannis; Di Lillo, Francesca; Russo, Paolo

    2018-06-07

    In cone-beam computed tomography dedicated to the breast (BCT), the mean glandular dose (MGD) is the dose metric of reference, evaluated from the measured air kerma by means of normalized glandular dose coefficients (DgN CT ). This work aimed at computing, for a simple breast model, a set of DgN CT values for monoenergetic and polyenergetic X-ray beams, and at validating the results vs. those for patient specific digital phantoms from BCT scans. We developed a Monte Carlo code for calculation of monoenergetic DgN CT coefficients (energy range 4.25-82.25 keV). The pendant breast was modelled as a cylinder of a homogeneous mixture of adipose and glandular tissue with glandular fractions by mass of 0.1%, 14.3%, 25%, 50% or 100%, enveloped by a 1.45 mm-thick skin layer. The breast diameter ranged between 8 cm and 18 cm. Then, polyenergetic DgN CT coefficients were analytically derived for 49-kVp W-anode spectra (half value layer 1.25-1.50 mm Al), as in a commercial BCT scanner. We compared the homogeneous models to 20 digital phantoms produced from classified 3D breast images. Polyenergetic DgN CT resulted 13% lower than most recent published data. The comparison vs. patient specific breast phantoms showed that the homogeneous cylindrical model leads to a DgN CT percentage difference between -15% and +27%, with an average overestimation of 8%. A dataset of monoenergetic and polyenergetic DgN CT coefficients for BCT was provided. Patient specific breast models showed a different volume distribution of glandular dose and determined a DgN CT 8% lower, on average, than homogeneous breast model. Copyright © 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  16. Quantitative cone beam X-ray luminescence tomography/X-ray computed tomography imaging

    International Nuclear Information System (INIS)

    Chen, Dongmei; Zhu, Shouping; Chen, Xueli; Chao, Tiantian; Cao, Xu; Zhao, Fengjun; Huang, Liyu; Liang, Jimin

    2014-01-01

    X-ray luminescence tomography (XLT) is an imaging technology based on X-ray-excitable materials. The main purpose of this paper is to obtain quantitative luminescence concentration using the structural information of the X-ray computed tomography (XCT) in the hybrid cone beam XLT/XCT system. A multi-wavelength luminescence cone beam XLT method with the structural a priori information is presented to relieve the severe ill-posedness problem in the cone beam XLT. The nanophosphors and phantom experiments were undertaken to access the linear relationship of the system response. Then, an in vivo mouse experiment was conducted. The in vivo experimental results show that the recovered concentration error as low as 6.67% with the location error of 0.85 mm can be achieved. The results demonstrate that the proposed method can accurately recover the nanophosphor inclusion and realize the quantitative imaging

  17. X-ray emission as a diagnostic from pseudospark-sourced electron beams

    Energy Technology Data Exchange (ETDEWEB)

    Bowes, D., E-mail: david.bowes@strath.ac.uk [Department of Physics, SUPA, University of Strathclyde, Glasgow G4 0NG (United Kingdom); Yin, H.; He, W.; Zhang, L.; Cross, A.W.; Ronald, K.; Phelps, A.D.R. [Department of Physics, SUPA, University of Strathclyde, Glasgow G4 0NG (United Kingdom); Chen, D.; Zhang, P. [Computed Tomography Lab, School of Mathematical Sciences, Capital Normal University, Beijing 100048 (China); Chen, X.; Li, D. [Department of Electronic Engineering, Queen Mary University of London, London E1 4NS (United Kingdom)

    2014-09-15

    X-ray emission has been achieved using an electron beam generated by a pseudospark low-pressure discharge and utilised as a diagnostic for beam detection. A 300 A, 34 kV PS-sourced electron beam pulse of 3 mm diameter impacting on a 0.1 mm-thick molybdenum target generated X-rays which were detected via the use of a small, portable X-ray detector. Clear X-ray images of a micro-sized object were captured using an X-ray photodetector. This demonstrates the inducement of proton induced X-ray emission (PIXE) not only as an indicator of beam presence but also as a future X-ray source for small-spot X-ray imaging of materials.

  18. Method for reducing x-ray background signals from insertion device x-ray beam position monitors

    Directory of Open Access Journals (Sweden)

    Glenn Decker

    1999-11-01

    Full Text Available A method is described that provides a solution to the long-standing problem of stray radiation-induced signals on photoemission-based x-ray beam position monitors (BPMs located on insertion device x-ray beam lines. The method involves the introduction of a chicane into the accelerator lattice that directs unwanted x radiation away from the photosensitive x-ray BPM blades. This technique has been implemented at the Advanced Photon Source, and experimental confirmation of the technique is provided.

  19. Development of confocal micro X-ray fluorescence instrument using two X-ray beams

    International Nuclear Information System (INIS)

    Tsuji, Kouichi; Nakano, Kazuhiko; Ding Xunliang

    2007-01-01

    A new confocal micro X-ray fluorescence instrument was developed. This instrument has two independent micro X-ray tubes with Mo targets. A full polycapillary X-ray lens was attached to each X-ray tube. Another half polycapillary lens was attached to a silicon drift X-ray detector (SDD). The focal spots of the three lenses were adjusted to a common position. The effects of the excitation of two X-ray beams were investigated. The instrument enabled highly sensitive three-dimensional X-ray fluorescence analysis. We confirmed that the X-ray fluorescence intensity from the sample increased by applying the two independent X-ray tubes in confocal configuration. Elemental depth profiling of black wheat was demonstrated with the result that each element in the surface coat of a wheat grain showed unique distribution

  20. X-ray scatter signatures for enhanced breast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kidane, Ghirmay; Speller, Robert; Royle, Gary [Medical Physics and Bioengineering Department, University College Landon, 11-20 Capper Street, London WC1E 6JA (United Kingdom)

    1999-12-31

    Conventional mammographic imaging suffers from a low specificity. The main cause is the small difference in the x-ray attenuation properties of healthy and diseased tissue leading to poor contrast in the image. It has been observed that additional information on breast tissue type can be obtained from x-ray diffraction effects. A study of excised normal and neoplastic breast tissue samples using x-ray diffraction apparatus has been observed that significant differences exist in the measured spectra between carcinoma and healthy tissue adjacent to the carcinoma. Such a difference allows tissue type to be characterised according to is diseased state. Furthermore the information can be applied to improve diagnosis. It is proposed that collection and analysis of the scattered x-rays present during a mammographic procedure can supply the additional information and be used to improve the image contrast. The ultimate aim of the project is to improve the specificity of x-ray mammography. (authors) 10 refs., 3 figs.

  1. Measurement of X-ray beam emittance using crystal optics at an X-ray undulator beamline

    CERN Document Server

    Kohmura, Y; Awaji, M; Tanaka, T; Hara, T; Goto, S; Ishikawa, T

    2000-01-01

    We present a method of using crystal optics to measure the emittance of the X-ray source. Two perfect crystals set in (++) configuration work as a high-resolution collimator. The phase-space diagram (i.e. beam cross-section and angular distribution) could be determined without any assumptions on the light source. When the measurement is done at short wavelength radiation from undulator, the electron beam emittance is larger than the diffraction limit of the X-rays. Therefore, the electron beam emittance could be estimated. The measurement was done with the hard X-rays of 18.5 and 55 keV from an undulator beamline, BL 47XU, of SPring-8. The horizontal emittance of the X-ray beam was estimated to be about 7.6 nmrad, close to the designed electron beam emittance of the storage ring (7 nmrad). Some portions of the instrumental functions, such as the scattering by filters and windows along the beamline and the slight bent of the crystal planes of the monochromator, could not be precisely evaluated, but an upper li...

  2. UHV photoelectron x-ray beam position monitor

    International Nuclear Information System (INIS)

    Johnson, E.D.; Oversluizen, T.

    1989-01-01

    As part of our research program to develop viable beam position monitors for both the X-ray and VUV beamlines at the NSLS, we have constructed vertical photon beam position monitors which are presently mounted in two front-ends in the X-ray ring. These area-type detectors are located before the safety shutters and are, therefore, able to monitor the beam position even during injection. The features of this type of monitor which contribute to its long-term stability, position sensitivity, and immunity to horizontal beam motion have been examined and will be discussed. 6 refs., 4 figs

  3. Measurement of X-ray beam emittance using crystal optics at an X-ray undulator beamline

    International Nuclear Information System (INIS)

    Kohmura, Yoshiki; Suzuki, Yoshio; Awaji, Mitsuhiro; Tanaka, Takashi; Hara, Toru; Goto, Shunji; Ishikawa, Tetsuya

    2000-01-01

    We present a method of using crystal optics to measure the emittance of the X-ray source. Two perfect crystals set in (++) configuration work as a high-resolution collimator. The phase-space diagram (i.e. beam cross-section and angular distribution) could be determined without any assumptions on the light source. When the measurement is done at short wavelength radiation from undulator, the electron beam emittance is larger than the diffraction limit of the X-rays. Therefore, the electron beam emittance could be estimated. The measurement was done with the hard X-rays of 18.5 and 55 keV from an undulator beamline, BL 47XU, of SPring-8. The horizontal emittance of the X-ray beam was estimated to be about 7.6 nmrad, close to the designed electron beam emittance of the storage ring (7 nmrad). Some portions of the instrumental functions, such as the scattering by filters and windows along the beamline and the slight bent of the crystal planes of the monochromator, could not be precisely evaluated, but an upper limit for the vertical emittance of the electron beam could be obtained as 0.14 nmrad

  4. An X-Ray computed tomography/positron emission tomography system designed specifically for breast imaging.

    Science.gov (United States)

    Boone, John M; Yang, Kai; Burkett, George W; Packard, Nathan J; Huang, Shih-ying; Bowen, Spencer; Badawi, Ramsey D; Lindfors, Karen K

    2010-02-01

    Mammography has served the population of women who are at-risk for breast cancer well over the past 30 years. While mammography has undergone a number of changes as digital detector technology has advanced, other modalities such as computed tomography have experienced technological sophistication over this same time frame as well. The advent of large field of view flat panel detector systems enable the development of breast CT and several other niche CT applications, which rely on cone beam geometry. The breast, it turns out, is well suited to cone beam CT imaging because the lack of bones reduces artifacts, and the natural tapering of the breast anteriorly reduces the x-ray path lengths through the breast at large cone angle, reducing cone beam artifacts as well. We are in the process of designing a third prototype system which will enable the use of breast CT for image guided interventional procedures. This system will have several copies fabricated so that several breast CT scanners can be used in a multi-institutional clinical trial to better understand the role that this technology can bring to breast imaging.

  5. Stabilization of synchrotron radiation x-ray beam by MOSTAB

    CERN Document Server

    Kudo, T P; Tanida, H; Furukawa, Y; Hirono, T; Ishikawa, T; Nishino, Y

    2003-01-01

    Monochromator stabilization (MOSTAB) is a feedback control system to stabilize an x-ray beam of synchrotron radiation. It applies a feedback voltage to a piezo electric transducer attached to a double-crystal monochromator. We developed MOSTAB modules and examined their performances using SPring-8 beamlines. The x-ray beam position stabilization using MOSTAB was realized simultaneously with the x-ray beam intensity stabilization. As an example of its application, we performed EXAFS measurement with MOSTAB. (author)

  6. WE-EF-207-06: Dedicated Cone-Beam Breast CT with Laterally-Shifted Detector: Monte Carlo Evaluation of X-Ray Scatter Distribution and Scatter-To-Primary Ratio

    International Nuclear Information System (INIS)

    Shi, L; Vedantham, S; Karellas, A

    2015-01-01

    Purpose: To determine the spatial distribution of x-ray scatter and scatter-to-primary ratio (SPR) in projections during cone-beam breast CT (CBBCT) with laterally-shifted detector that results in coronal (fan-angle) truncation. Methods: We hypothesized that CBBCT with coronal truncation would lower SPR due to reduction in irradiated breast volume, and that the location of maximum x-ray scatter fluence (scatter-peak) in the detector plane can be determined from the ratio of irradiated-to-total breast volume, breast dimensions and system geometry. Monte Carlo simulations (GEANT4) reflecting a prototype CBBCT system were used to record the position-dependent primary and scatter x-ray photon fluence incident on the detector without coronal truncation (full fan-angle, 2f=24-degrees) and with coronal truncation (fan-angle, f+ f=12+2.7-degrees). Semi-ellipsoidal breasts (10/14/18-cm diameter, chest-wall to nipple length: 0.75xdiameter, 2%/14%/100% fibroglandular content) aligned with the axis-of-rotation (AOR) were modeled. Mono-energy photons were simulated and weighted for 2 spectra (49kVp, 1.4-mm Al HVL; 60kVp, 3.76-mm Al HVL). In addition to SPR, the scatter maps were analyzed to identify the location of the scatter-peak. Results: For CBBCT without fan-angle truncation, the scatter-peaks were aligned with the projection of the AOR onto the detector for all breasts. With truncated fan-beam, the scatter-peaks were laterally-shifted from the projection of the AOR along the fan-angle direction by 14/38/70-pixels for 10/14/18-cm diameter breasts. The corresponding theoretical shifts were 14.8/39.7/68-pixels (p=0.47, 2-tailed paired-ratio t-test). Along the cone-angle, the shift in scatter-peaks between truncated and full-fan angle CBBCT were 2/2/4 -pixels for 10/14/18-cm diameter breasts. CBBCT with fan-angle truncation reduced SPR by 14/22/28% for 10/14/18-cm diameter breasts. 60kVp reduced SPR by 21–25% compared to 49kVp. Peak SPR for CBBCT with fan-angle truncation

  7. X-ray beam size measurements on the Advanced Test Accelerator

    International Nuclear Information System (INIS)

    Struve, K.W.; Chambers, F.W.; Lauer, E.J.; Slaughter, D.R.

    1986-01-01

    The electron beam size has been determined on the Advanced Test Accelerator (ATA) by intercepting the beam with a target and measuring the resulting x-ray intensity as a function of time as the target is moved through the beam. Several types of targets have been used. One is a tantalum rod which extends completely across the drift chamber. Another is a tungsten powder filled carbon crucible. Both of these probes are moved from shot to shot so that the x-ray signal intensity varies with probe position. A third is a larger tantalum disk which is inserted on beam axis to allow determining beam size on a one shot basis. The x-ray signals are detected with an MCP photomultiplier tube located at 90 0 to the beamline. It is sufficiently shielded to reject background x-rays and neutrons. The signals were digitized, recorded and later unfolded to produce plots of x-ray intensity versus probe position for several times during the pulse. The presumption that the x-ray intensity is proportional to beam current density is checked computationally. Details of the probe construction and PMT shielding, as well as sample measurements are given

  8. X-ray beam qualities for dental radiology purposes

    International Nuclear Information System (INIS)

    Santos, Marcus Aurelio P. dos; Fragoso, Maria da Conceicao de F.; Lima, Ricardo de A.; Hazim, Clovis A.

    2009-01-01

    In order to establish characteristics or properties of equipment for diagnostic radiology, e.g. ion chambers and semiconductor detectors, calibration laboratories offer a set of well-defined radiation conditions, called X-ray qualities, which can be used for many Physics studies and medical purposes. The standardization of radiation qualities has been carried out in several fields of study, but little attention has been given to the area of dental radiology, mainly for medical and physical applications using single-phase units with half-wave rectification. For this reason, a single-phase dental unit with adjustable peak voltage and tube current, called 'variable potential X-ray equipment', was developed aiming to define X-ray beam qualities for test and calibrations purposes. X-ray spectra at 50, 60 and 70 kVp were determined by using a CdTe detector and compared with those obtained for ten commercial X-ray dental units. As a result of this study, a set of X-ray qualities for the variable potential X-ray equipment was determined. The X-ray qualities spectra were utilized as reference for determination of a new set of X-ray qualities characterized for a constant potential X-ray equipment. Thus, sets of X-ray qualities were standardized and implemented in two X-ray laboratories: one with the variable potential X-ray equipment and other with constant potential X-ray equipment. These reference X-ray beam qualities should be used for test and calibration purposes involving scientific studies and services. (author)

  9. Dual resolution cone beam breast CT: A feasibility study

    International Nuclear Information System (INIS)

    Chen Lingyun; Shen Youtao; Lai, Chao-Jen; Han Tao; Zhong Yuncheng; Ge Shuaiping; Liu Xinming; Wang Tianpeng; Yang, Wei T.; Whitman, Gary J.; Shaw, Chris C.

    2009-01-01

    Purpose: In this study, the authors investigated the feasibility of a dual resolution volume-of-interest (VOI) cone beam breast CT technique and compared two implementation approaches in terms of dose saving and scatter reduction. Methods: With this technique, a lead VOI mask with an opening is inserted between the x-ray source and the breast to deliver x-ray exposure to the VOI while blocking x rays outside the VOI. A CCD detector is used to collect the high resolution projection data of the VOI. Low resolution cone beam CT (CBCT) images of the entire breast, acquired with a flat panel (FP) detector, were used to calculate the projection data outside the VOI with the ray-tracing reprojection method. The Feldkamp-Davis-Kress filtered backprojection algorithm was used to reconstruct the dual resolution 3D images. Breast phantoms with 180 μm and smaller microcalcifications (MCs) were imaged with both FP and FP-CCD dual resolution CBCT systems, respectively. Two approaches of implementing the dual resolution technique, breast-centered approach and VOI-centered approach, were investigated and evaluated for dose saving and scatter reduction with Monte Carlo simulation using a GEANT4 package. Results: The results showed that the breast-centered approach saved more breast absorbed dose than did VOI-centered approach with similar scatter reduction. The MCs in fatty breast phantom, which were invisible with FP CBCT scan, became visible with the FP-CCD dual resolution CBCT scan. Conclusions: These results indicate potential improvement of the image quality inside the VOI with reduced breast dose both inside and outside the VOI.

  10. Automated Area Beam Equalization Mammography for Improved Imaging of Dense Breasts

    National Research Council Canada - National Science Library

    Molloi, Sabee

    2005-01-01

    ...) because of degraded contrast from large scatter intensities and relatively high noise. Area x-ray beam equalization can improve image quality by increasing the x-ray exposure to underpenetrated regions without increasing the exposure to the breast regions...

  11. Automated Area Beam Equalization Mammography for Improved Imaging of Dense Breast

    National Research Council Canada - National Science Library

    Molloi, Sabee

    2004-01-01

    ...) because of degraded contrast from large scatter intensities and relatively high noise. Area x-ray beam equalization can improve image quality by increasing the x-ray exposure to under-penetrated regions without increasing the exposure to other breast regions...

  12. Accelerators for E-beam and X-ray processing

    Energy Technology Data Exchange (ETDEWEB)

    Auslender, V.L. E-mail: auslen@inp.nsk.su; Bryazgin, A.A.; Faktorovich, B.L.; Gorbunov, V.A.; Kokin, E.N.; Korobeinikov, M.V.; Krainov, G.S.; Lukin, A.N.; Maximov, S.A.; Nekhaev, V.E.; Panfilov, A.D.; Radchenko, V.N.; Tkachenko, V.O.; Tuvik, A.A.; Voronin, L.A

    2002-03-01

    During last years the demand for pasteurization and desinsection of various food products (meat, chicken, sea products, vegetables, fruits, etc.) had increased. The treatment of these products in industrial scale requires the usage of powerful electron accelerators with energy 5-10 MeV and beam power at least 50 kW or more. The report describes the ILU accelerators with energy range up to 10 MeV and beam power up to 150 kW.The different irradiation schemes in electron beam and X-ray modes for various products are described. The design of the X-ray converter and 90 deg. beam bending system are also given.

  13. A submicron synchrotron X-ray beam generated by capillary optics

    International Nuclear Information System (INIS)

    Engstroem, P.; Larsson, S.; Rindby, A.; Buttkewitz, A.; Garbe, S.; Gaul, G.; Knoechel, A.; Lechtenberg, F.; Deutsches Elektronen-Synchrotron

    1991-01-01

    A novel capillary optics technique for focusing synchrotron X-ray beams has been applied in an experiment performed at the DORIS storage ring at HASYLAB. This new technqiue, which utilizes the total reflection properties of X-rays inside small capillaries, has recently been applied to generate microbeams of X-rays, with a beam size down to about 10 μm using conventional X-ray tubes. The result from our recent experiment shows that capillary optics can also be used to generate a submicron beam of X-rays from a synchrotron light source. A description of the capillary unit, and the alignment procedure is given. The influence of the thermal load on the device caused by the intense flux of synchrotron radiation will be discussed. Future perspectives of the capillary techniques as applied to synchrotron radiation will be discussed. (orig.)

  14. A new beamstop for microfocus X-ray capillary beams

    Energy Technology Data Exchange (ETDEWEB)

    Englich, Ulrich, E-mail: ue22@cornell.edu [Cornell University, Macromolecular Diffraction at CHESS (MacCHESS), Cornell High Energy Synchrotron Source, 200L Wilson Laboratory, Ithaca, NY 14853 (United States); Revesz, Peter [Cornell University, Cornell High Energy Synchrotron Source, Ithaca, NY 14853 (United States); Miller, William [Cornell University, Macromolecular Diffraction at CHESS (MacCHESS), Cornell High Energy Synchrotron Source, 200L Wilson Laboratory, Ithaca, NY 14853 (United States)

    2011-09-01

    In order to accurately measure the photon flux and to assist in aligning the beam, we have designed a modified beamstop device based on a photo diode integrated with the beamstop. The beamstop contains a small CdWO{sub 4} crystal that completely stops the X-rays and at the same time produces photoluminescence proportional to the X-ray flux. The light is then guided to a photosensitive diode using a flexible light pipe to monitor the flux. With this device we achieve the goal of stopping the primary X-ray beam and simultaneously monitoring the X-ray intensity, thus eliminating the need for integrating ion-chambers into the capillary or collimator mount.

  15. Cone beam x-ray luminescence computed tomography: a feasibility study.

    Science.gov (United States)

    Chen, Dongmei; Zhu, Shouping; Yi, Huangjian; Zhang, Xianghan; Chen, Duofang; Liang, Jimin; Tian, Jie

    2013-03-01

    The appearance of x-ray luminescence computed tomography (XLCT) opens new possibilities to perform molecular imaging by x ray. In the previous XLCT system, the sample was irradiated by a sequence of narrow x-ray beams and the x-ray luminescence was measured by a highly sensitive charge coupled device (CCD) camera. This resulted in a relatively long sampling time and relatively low utilization of the x-ray beam. In this paper, a novel cone beam x-ray luminescence computed tomography strategy is proposed, which can fully utilize the x-ray dose and shorten the scanning time. The imaging model and reconstruction method are described. The validity of the imaging strategy has been studied in this paper. In the cone beam XLCT system, the cone beam x ray was adopted to illuminate the sample and a highly sensitive CCD camera was utilized to acquire luminescent photons emitted from the sample. Photons scattering in biological tissues makes it an ill-posed problem to reconstruct the 3D distribution of the x-ray luminescent sample in the cone beam XLCT. In order to overcome this issue, the authors used the diffusion approximation model to describe the photon propagation in tissues, and employed the sparse regularization method for reconstruction. An incomplete variables truncated conjugate gradient method and permissible region strategy were used for reconstruction. Meanwhile, traditional x-ray CT imaging could also be performed in this system. The x-ray attenuation effect has been considered in their imaging model, which is helpful in improving the reconstruction accuracy. First, simulation experiments with cylinder phantoms were carried out to illustrate the validity of the proposed compensated method. The experimental results showed that the location error of the compensated algorithm was smaller than that of the uncompensated method. The permissible region strategy was applied and reduced the reconstruction error to less than 2 mm. The robustness and stability were then

  16. Constancy check of beam quality in conventional diagnostic X-ray equipment

    International Nuclear Information System (INIS)

    Costa, Alessandro M.; Badin, Romulo S.; Leite, Marina S.; Caldas, Linda V.E.

    2008-01-01

    A tandem ionization chamber was developed for quality control programs of X-ray equipment used in conventional radiography and mammography. A methodology for the use of the tandem chamber in the constancy check of diagnostic X-ray beam qualities was established. The application at a medical X-ray imaging facility of this established methodology is presented. The use of the tandem chamber in the constancy check of diagnostic X-ray beam qualities is a useful method to control the performance of the X-ray equipment

  17. Single-shot beam-position monitor for x-ray free electron laser

    Science.gov (United States)

    Tono, Kensuke; Kudo, Togo; Yabashi, Makina; Tachibana, Takeshi; Feng, Yiping; Fritz, David; Hastings, Jerome; Ishikawa, Tetsuya

    2011-02-01

    We have developed an x-ray beam-position monitor for detecting the radiation properties of an x-ray free electron laser (FEL). It is composed of four PIN photodiodes that detect backscattered x-rays from a semitransparent diamond film placed in the beam path. The signal intensities from the photodiodes are used to compute the beam intensity and position. A proof-of-principle experiment at a synchrotron light source revealed that the error in the beam position is reduced to below 7 μm by using a nanocrystal diamond film prepared by plasma-enhanced chemical vapor deposition. Owing to high dose tolerance and transparency of the diamond film, the monitor is suitable for routine diagnostics of extremely intense x-ray pulses from the FEL.

  18. Hard X-ray emission spectroscopy with pink beam

    Energy Technology Data Exchange (ETDEWEB)

    Kvashnina, Kristina O.; Rossberg, Andre; Exner, Joerg; Scheinost, Andreas C. [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Molecular Structures

    2017-06-01

    Valence-band X-ray emission spectroscopy (XES) with a ''pink beam'', i.e. a beam with large energy bandwidth produced by a double-multilayer monochromator, is introduced here to overcome the weak count rate of monochromatic beams produced by conventional double-crystal monochromators. Our results demonstrate that - in spite of the large bandwidth in the order of 100 eV - the high spectral resolution of the Johann-type spectrometer is maintained, while the two orders of magnitude higher flux greatly reduces the required counting time. The short working distance Johann-type X-ray emission spectrometer and multilayer monochromator is available at ROBL.

  19. Beam line for experiments with coherent soft x-rays

    International Nuclear Information System (INIS)

    Howells, M.R.; Kirz, J.; Krinsky, S.

    1982-12-01

    The advantages of coherent soft x-rays for three-dimensional imaging of biological specimens are discussed, the x-ray source requirements are described, and the general design of the beam line and its optical system are given

  20. X-ray topography using the forward transmitted beam under multiple-beam diffraction conditions

    Energy Technology Data Exchange (ETDEWEB)

    Tsusaka, Y., E-mail: tsusaka@sci.u-hyogo.ac.jp; Takano, H. [Graduate School of Material Science, University of Hyogo, 3-2-1, Kouto, Kamigori, Hyogo 678-1297 (Japan); Takeda, S. [SPring-8 Service Co., Ltd., 1-20-5, Kouto, Shingu, Tatsuno, Hyogo 679-5165 (Japan); Yokoyama, K.; Matsui, J. [Synchrotron Radiation Nanotechnology Center, University of Hyogo, 1-490-2, Kouto, Shingu, Tatsuno, Hyogo 679-5165 (Japan); Kagoshima, Y. [Graduate School of Material Science, University of Hyogo, 3-2-1, Kouto, Kamigori, Hyogo 678-1297 (Japan); Synchrotron Radiation Nanotechnology Center, University of Hyogo, 1-490-2, Kouto, Shingu, Tatsuno, Hyogo 679-5165 (Japan)

    2016-02-15

    X-ray topographs are taken for a sapphire wafer with the [0001] surface normal, as an example, by forward transmitted synchrotron x-ray beams combined with two-dimensional electronic arrays in the x-ray detector having a spatial resolution of 1 μm. They exhibit no shape deformation and no position shift of the dislocation lines on the topographs. Since the topography is performed under multiple-beam diffraction conditions, the topographic images of a single diffraction (two-wave approximation condition) or plural diffractions (six-wave approximation condition) can be recorded without large specimen position changes. As usual Lang topographs, it is possible to determine the Burgers vector of each dislocation line. Because of high parallelism of the incoming x-rays and linear sensitivity of the electronic arrays to the incident x-rays, the present technique can be used to visualize individual dislocations in single crystals of the dislocation density as high as 1 × 10{sup 5} cm{sup −2}.

  1. An x-ray technique for precision laser beam synchronization

    International Nuclear Information System (INIS)

    Landen, O.L.; Lerche, R.A.; Hay, R.G.; Hammel, B.A.; Kalantar, D.; Cable, M.D.

    1994-01-01

    A new x-ray technique for recording the relative arrival times of multiple laser beams at a common target with better than ± 10 ps accuracy has been implemented at the Nova laser facility. 100 ps, 3ω Nova beam are focused to separate locations on a gold ribbon target viewed from the side. The measurement consists of using well characterized re-entrant x-ray streak cameras for 1-dimensional streaked imaging of the > 3 keV x-rays emanating from these isolated laser plasmas. After making the necessary correction for the differential laser, x-ray and electron transit times involved, timing offsets as low as ± 7 ps are resolved, and on subsequent shots, corrected for, verified and independently checked. This level of synchronization proved critical in meeting the power balance requirements for indirectly-driven pulse-shaped Nova implosions

  2. A Study on Mono-energetic Beam Source Using Characteristic X-ray for Substance Identification System

    International Nuclear Information System (INIS)

    Lee, Hwan Soo

    2009-02-01

    A new mono-energetic beam source was developed by using characteristic X-ray for improving performance of the substance identification system. Most of inspection systems use X-ray tubes for their source modules. However, the broad energy spectrum of X-ray tube causes an increase of uncertainty. In this study, it was found that mono-energetic beam sources can be generated by using X-ray tube and the designed target filter assembly. In order to investigate the monoenergetic beam source, the sensitivity study was conducted with a series of different X-ray tube potentials, radiator and filter materials using Monte Carlo simulation. The developed beam sources have a mono-energy peak at 69 keV, 78 keV and 99 keV, and they are named as characteristic X-ray beam BEAM69, BEAM78 and BEAM99, respectively. The characteristic X-ray beam intensity was over thirty three times more than that of hardening beam used previous work at Hanyang University. And BEAM69 and BEAM99 were applied to the substance identification system as a source. The relative error between results of characteristic X-ray beams and 69 keV and 99 keV photons was about 2% on the average for five unknown materials. In comparison with experiment results by using hardening beam, characteristic X-ray beam achieves better accuracy which is about 6.46 % on the average. Hence, it is expected that the developed characteristic X-ray beam source helps lower uncertainty of the inspection system, and the inspection time will be reduced considerably due to its high beam intensity

  3. Design of parallel dual-energy X-ray beam and its performance for security radiography

    International Nuclear Information System (INIS)

    Kim, Kwang Hyun; Myoung, Sung Min; Chung, Yong Hyun

    2011-01-01

    A new concept of dual-energy X-ray beam generation and acquisition of dual-energy security radiography is proposed. Erbium (Er) and rhodium (Rh) with a copper filter were positioned in front of X-ray tube to generate low- and high-energy X-ray spectra. Low- and high-energy X-rays were guided to separately enter into two parallel detectors. Monte Carlo code of MCNPX was used to derive an optimum thickness of each filter for improved dual X-ray image quality. It was desired to provide separation ability between organic and inorganic matters for the condition of 140 kVp/0.8 mA as used in the security application. Acquired dual-energy X-ray beams were evaluated by the dual-energy Z-map yielding enhanced performance compared with a commercial dual-energy detector. A collimator for the parallel dual-energy X-ray beam was designed to minimize X-ray beam interference between low- and high-energy parallel beams for 500 mm source-to-detector distance.

  4. Generation of linearly polarized resonant transition radiation X-ray beam

    International Nuclear Information System (INIS)

    Yajima, Kazuaki; Awata, Takaaki; Ikeda, Mitsuharu; Ikeda, Kenichi; Yogo, Akifumi; Itoh, Akio; Imanishi, Nobutsugu

    2000-01-01

    We have proposed a method to generate almost linearly polarized resonant transition radiation X rays by using a rectangular slit placed on an electron beam axis. Our calculation predicted that the linearity is 93.5% for the resonant transition radiation X-ray beam extracted through a slit of 0.5 mrad long and 0.2 mrad wide in case of 1-GeV electron beam irradiating a 7.5-μm thick Kapton foil stack. (author)

  5. Generation of linearly polarized resonant transition radiation X-ray beam

    Energy Technology Data Exchange (ETDEWEB)

    Yajima, Kazuaki; Awata, Takaaki; Ikeda, Mitsuharu; Ikeda, Kenichi; Yogo, Akifumi; Itoh, Akio; Imanishi, Nobutsugu [Kyoto Univ. (Japan). Dept. of Nuclear Engineering

    2000-03-01

    We have proposed a method to generate almost linearly polarized resonant transition radiation X rays by using a rectangular slit placed on an electron beam axis. Our calculation predicted that the linearity is 93.5% for the resonant transition radiation X-ray beam extracted through a slit of 0.5 mrad long and 0.2 mrad wide in case of 1-GeV electron beam irradiating a 7.5-{mu}m thick Kapton foil stack. (author)

  6. Development of a multi-lane X-ray mirror providing variable beam sizes

    Energy Technology Data Exchange (ETDEWEB)

    Laundy, D., E-mail: david.laundy@diamond.ac.uk; Sawhney, K.; Nistea, I.; Alcock, S. G.; Pape, I.; Sutter, J.; Alianelli, L.; Evans, G. [Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot OX11 0DE (United Kingdom)

    2016-05-15

    Grazing incidence mirrors are used on most X-ray synchrotron beamlines to focus, collimate or suppress harmonics. Increasingly beamline users are demanding variable beam shapes and sizes at the sample position. We have now developed a new concept to rapidly vary the beam size and shape of a focused X-ray beam. The surface of an elliptically figured mirror is divided into a number of laterally separated lanes, each of which is given an additional longitudinal height profile calculated to shape the X-ray beam to a top-hat profile in the focal plane. We have now fabricated two prototype mirrors and present the results of metrology tests and measurements made with one of the mirrors focusing the X-rays on a synchrotron beamline. We envisage that such mirrors could be widely applied to rapid beam-size switching on many synchrotron beamlines.

  7. TU-EF-207-05: Dedicated Cone-beam Breast CT

    International Nuclear Information System (INIS)

    Vedantham, S.

    2015-01-01

    mode due to lower photon fluence per projection. This may require fast-frame acquisition and symmetric or asymmetric pixel binning in some systems. Recent studies investigated the performance of increased conversion layer thickness for contrast-enhanced imaging of the breast in dual-energy acquisition mode. In other direct conversion detectors operating in the avalanche mode, sensitivities close to the single photon response are also explored for mammography and breast tomosynthesis. The potential advantages and challenges of this approach are described. Dedicated breast CT brings x-ray imaging of the breast to true tomographic 3D imaging. It can eliminate the tissue superposition problem and does not require physical compression of the breast. Using cone beam geometry and a flat-panel detector, several hundred projections are acquired and reconstructed to near isotropic voxels. Multiplanar reconstruction facilitates viewing the breast volume in any desired orientation. Ongoing clinical studies, the current state-of-the art, and research to advance the technology are described. Learning Objectives: To understand the ongoing developments in x-ray imaging of the breast To understand the approaches and applications of spectral mammography To understand the potential advantages of distributed x-ray source arrays for digital breast tomosynthesis To understand the ongoing developments in detector technology for digital mammography and breast tomosynthesis To understand the current state-of-the-art for dedicated cone-beam breast CT and research to advance the technology. Research collaboration with Koning Corporation

  8. TU-EF-207-05: Dedicated Cone-beam Breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Vedantham, S. [Univ. of Massachusetts Medical School (United States)

    2015-06-15

    mode due to lower photon fluence per projection. This may require fast-frame acquisition and symmetric or asymmetric pixel binning in some systems. Recent studies investigated the performance of increased conversion layer thickness for contrast-enhanced imaging of the breast in dual-energy acquisition mode. In other direct conversion detectors operating in the avalanche mode, sensitivities close to the single photon response are also explored for mammography and breast tomosynthesis. The potential advantages and challenges of this approach are described. Dedicated breast CT brings x-ray imaging of the breast to true tomographic 3D imaging. It can eliminate the tissue superposition problem and does not require physical compression of the breast. Using cone beam geometry and a flat-panel detector, several hundred projections are acquired and reconstructed to near isotropic voxels. Multiplanar reconstruction facilitates viewing the breast volume in any desired orientation. Ongoing clinical studies, the current state-of-the art, and research to advance the technology are described. Learning Objectives: To understand the ongoing developments in x-ray imaging of the breast To understand the approaches and applications of spectral mammography To understand the potential advantages of distributed x-ray source arrays for digital breast tomosynthesis To understand the ongoing developments in detector technology for digital mammography and breast tomosynthesis To understand the current state-of-the-art for dedicated cone-beam breast CT and research to advance the technology. Research collaboration with Koning Corporation.

  9. Anomalous x-ray radiation of beam plasma

    International Nuclear Information System (INIS)

    Dimitrov, S.K.; Zavyalov, M.A.; Mikhin, S.G.; Tarasenkov, V.A.; Telkovskij, V.G.; Khrabrov, V.A.

    1985-01-01

    The properties of non-equilibrium stationary plasma under the conditions of the planned plasma-chemical reactors based on beam-plasma discharge were investigated. The x-ray spectrum of the beam-plasma was measured and anomalous spectral properties were analyzed. Starting with some critical pressure the anomalous radiation was added to the classical bremsstrahlung spectrum. The occurrence of anomalous radiation can be used to diagnose the condition of beam transportation in such systems. (D.Gy.)

  10. Cone-beam x-ray luminescence computed tomography based on x-ray absorption dosage

    Science.gov (United States)

    Liu, Tianshuai; Rong, Junyan; Gao, Peng; Zhang, Wenli; Liu, Wenlei; Zhang, Yuanke; Lu, Hongbing

    2018-02-01

    With the advances of x-ray excitable nanophosphors, x-ray luminescence computed tomography (XLCT) has become a promising hybrid imaging modality. In particular, a cone-beam XLCT (CB-XLCT) system has demonstrated its potential in in vivo imaging with the advantage of fast imaging speed over other XLCT systems. Currently, the imaging models of most XLCT systems assume that nanophosphors emit light based on the intensity distribution of x-ray within the object, not completely reflecting the nature of the x-ray excitation process. To improve the imaging quality of CB-XLCT, an imaging model that adopts an excitation model of nanophosphors based on x-ray absorption dosage is proposed in this study. To solve the ill-posed inverse problem, a reconstruction algorithm that combines the adaptive Tikhonov regularization method with the imaging model is implemented for CB-XLCT reconstruction. Numerical simulations and phantom experiments indicate that compared with the traditional forward model based on x-ray intensity, the proposed dose-based model could improve the image quality of CB-XLCT significantly in terms of target shape, localization accuracy, and image contrast. In addition, the proposed model behaves better in distinguishing closer targets, demonstrating its advantage in improving spatial resolution.

  11. SU-F-I-76: Fluoroscopic X-Ray Beam Profiles for Spectra Incorporating Copper Filtration

    Energy Technology Data Exchange (ETDEWEB)

    Wunderle, K [Cleveland Clinic Foundation, Cleveland, OH (United States); Wayne State University School of Medicine, Detroit, MI (United States); Godley, A; Shen, Z; Dong, F [Cleveland Clinic Foundation, Cleveland, OH (United States); Rakowski, J [Wayne State University School of Medicine, Detroit, MI (United States)

    2016-06-15

    Purpose: The purpose of this investigation is to characterize and quantify X-ray beam profiles for fluoroscopic x-ray beam spectra incorporating spectral (copper) filtration. Methods: A PTW (Freiburg, Germany) type 60016 silicon diode detector and PTW MP3 water tank were used to measure X-ray beam profiles for 60, 80, 100 and 120 kVp x-ray beams at five different copper filtration thicknesses ranging from 0–0.9 mm at 22 and 42 cm fields of view and depths of 1, 5, and 10 cm in both the anode-cathode axis (inplane) and cross-plane directions. All measurements were acquired on a Siemens (Erlangen, Germany) Artis ZeeGo fluoroscope inverted from the typical orientation providing an x-ray beam originating from above the water surface with the water level set at 60 cm from the focal spot. Results: X-ray beam profiles for beam spectra without copper filtration compared well to previously published data by Fetterly et al. [Med Phys, 28, 205 (2001)]. Our data collection benefited from the geometric orientation of the fluoroscope, providing a beam perpendicular to the tank water surface, rather than through a thin side wall as did the previously mentioned study. Profiles for beams with copper filtration were obtained which have not been previously investigated and published. Beam profiles in the anode-cathode axis near the surface and at lower x-ray energy exhibited substantial heel effect, which became less pronounced at greater depth. At higher energy with copper filtration in the beam, the dose falloff out-of-field became less pronounced, as would be anticipated given higher scatter photon energy. Conclusion: The x-ray beam profile data for the fluoroscopic x-ray beams incorporating copper filtration are intended for use as reference data for estimating doses to organs or soft tissue, including fetal dose, involving similar beam qualities or for comparison with mathematical models.

  12. Controlling X-ray beam trajectory with a flexible hollow glass fibre

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Yoshihito, E-mail: yotanaka@riken.jp [RIKEN, 1-1-1 Kouto, Sayo-cho, Hyogo 679-5148 (Japan); Kwansei Gakuin University, Gakuen, Sanda, Hyogo 669-1337 (Japan); Nakatani, Takashi; Onitsuka, Rena [Kwansei Gakuin University, Gakuen, Sanda, Hyogo 669-1337 (Japan); Sawada, Kei [RIKEN, 1-1-1 Kouto, Sayo-cho, Hyogo 679-5148 (Japan); Takahashi, Isao [Kwansei Gakuin University, Gakuen, Sanda, Hyogo 669-1337 (Japan)

    2014-01-01

    X-ray beam trajectory control has been performed by using a 1.5 m-long flexible hollow glass fibre. A two-dimensional scan of a synchrotron radiation beam was demonstrated for X-ray absorption mapping. A metre-length flexible hollow glass fibre with 20 µm-bore and 1.5 mm-cladding diameters for transporting a synchrotron X-ray beam and controlling the trajectory has been examined. The large cladding diameter maintains a moderate curvature to satisfy the shallow glancing angle of total reflection. The observed transmission efficiency was more than 20% at 12.4 keV. As a demonstration, a wide-area scan of a synchrotron radiation beam was performed to identify the elements for a fixed metal film through its absorption spectra.

  13. An MCNP-based model of a medical linear accelerator x-ray photon beam.

    Science.gov (United States)

    Ajaj, F A; Ghassal, N M

    2003-09-01

    The major components in the x-ray photon beam path of the treatment head of the VARIAN Clinac 2300 EX medical linear accelerator were modeled and simulated using the Monte Carlo N-Particle radiation transport computer code (MCNP). Simulated components include x-ray target, primary conical collimator, x-ray beam flattening filter and secondary collimators. X-ray photon energy spectra and angular distributions were calculated using the model. The x-ray beam emerging from the secondary collimators were scored by considering the total x-ray spectra from the target as the source of x-rays at the target position. The depth dose distribution and dose profiles at different depths and field sizes have been calculated at a nominal operating potential of 6 MV and found to be within acceptable limits. It is concluded that accurate specification of the component dimensions, composition and nominal accelerating potential gives a good assessment of the x-ray energy spectra.

  14. X-ray scattering for the characterization of lyophilized breast tissue samples

    International Nuclear Information System (INIS)

    Elshemey, Wael M.; Mohamed, Fayrouz S.; Khater, Ibrahim M.

    2013-01-01

    This work investigates the possibility of characterizing breast cancer by measuring the X-ray scattering profiles of lyophilized excised breast tissue samples. Since X-ray scattering from water-rich tissue is dominated by scattering from water, the removal of water by lyophilization would enhance the characterization process. In the present study, X-ray scattering profiles of 22 normal, 22 malignant and 10 benign breast tissue samples are measured. The cut-offs of scatter diagrams, sensitivity, specificity and diagnostic accuracy of three characterization parameters (full width at half maximum (FWHM) for the peak at 1.1 nm −1 , area under curve (AUC), and ratio of 1st to 2nd scattering peak intensities (I 1 /I 2 %)) are calculated and compared to the data from non-lyophilized samples. Results show increased sensitivity (up to 100%) of the present data on lyophilized breast tissue samples compared to previously reported data for non-lyophilized samples while the specificity (up to 95.4%), diagnostic accuracy (up to 95.4%) and receiver operating characteristic (ROC) curve values (up to 0.9979) for both sets of data are comparable. The present study shows significant differences between normal samples and each of malignant and benign samples. Only subtle differences exist between malignant and benign lyophilized breast tissue samples where FWHM=0.7±0.1 and 0.8±0.3, AUC=1.3±0.2 and 1.4±0.2 and I 1 /I 2 %=44.9±11.0 and 52.4±7.6 for malignant and benign samples respectively. - Highlights: • X-ray scattering profiles of breast tissue samples are acquired. • Three X-ray profile characterization parameters are calculated. • The cut-offs, sensitivity, specificity and diagnostic accuracy are calculated. • They are compared to the data from non-lyophilized samples. • Results show increased sensitivity in case of lyophilized samples

  15. Exposure reduction in general dental practice using digital x-ray imaging system for intraoral radiography with additional x-ray beam filter

    International Nuclear Information System (INIS)

    Shibuya, Hitoshi; Mori, Toshimichi; Hayakawa, Yoshihiko; Kuroyanagi, Kinya; Ota, Yoshiko

    1997-01-01

    To measure exposure reduction in general dental practice using digital x-ray imaging systems for intraoral radiography with additional x-ray beam filter. Two digital x-ray imaging systems, Pana Digital (Pana-Heraus Dental) and CDR (Schick Technologies), were applied for intraoral radiography in general dental practice. Due to the high sensitivity to x-rays, additional x-ray beam filters for output reduction were used for examination. An Orex W II (Osada Electric Industry) x-ray generator was operated at 60 kVp, 7 mA. X-ray output (air-kerma; Gy) necessary for obtaining clinically acceptable images was measured at 0 to 20 cm in 5 cm steps from the cone tip using an ionizing chamber type 660 (Nuclear Associates) and compared with those for Ektaspeed Plus film (Eastman Kodak). The Pana Digital system was used with the optional filter supplied by Pana-Heraus Dental which reduced the output to 38%. The exposure necessary to obtain clinically acceptable images was only 40% of that for the film. The CDR system was used with the Dental X-ray Beam Filter Kit (Eastman Kodak) which reduced the x-ray output to 30%. The exposure necessary to obtain clinically acceptable images was only 20% of that for the film. The two digital x-ray imaging systems, Pana Digital and CDR, provided large dose savings (60-80%) compared with Ektaspeed Plus film when applied for intraoral radiography in general dental practice. (author)

  16. Using x-ray mammograms to assist in microwave breast image interpretation.

    Science.gov (United States)

    Curtis, Charlotte; Frayne, Richard; Fear, Elise

    2012-01-01

    Current clinical breast imaging modalities include ultrasound, magnetic resonance (MR) imaging, and the ubiquitous X-ray mammography. Microwave imaging, which takes advantage of differing electromagnetic properties to obtain image contrast, shows potential as a complementary imaging technique. As an emerging modality, interpretation of 3D microwave images poses a significant challenge. MR images are often used to assist in this task, and X-ray mammograms are readily available. However, X-ray mammograms provide 2D images of a breast under compression, resulting in significant geometric distortion. This paper presents a method to estimate the 3D shape of the breast and locations of regions of interest from standard clinical mammograms. The technique was developed using MR images as the reference 3D shape with the future intention of using microwave images. Twelve breast shapes were estimated and compared to ground truth MR images, resulting in a skin surface estimation accurate to within an average Euclidean distance of 10 mm. The 3D locations of regions of interest were estimated to be within the same clinical area of the breast as corresponding regions seen on MR imaging. These results encourage investigation into the use of mammography as a source of information to assist with microwave image interpretation as well as validation of microwave imaging techniques.

  17. New X-ray beam position monitors with submicron resolution utilizing imaging of scattered X-rays at CHESS

    International Nuclear Information System (INIS)

    Revesz, Peter; Temnykh, Alexander B.; Pauling, Alan K.

    2011-01-01

    At CHESS' A, F and G wiggler beam lines three new video beam position monitors (VBPMs) have been commissioned. These new VBPMs utilize X-rays scattered from the graphite filter (A and F line) or from a beryllium window (G-line) as the white wiggler beam passes through them. As the X-rays scatter in all directions from the scattering medium, a slit camera creates an image of the beam's footprint on a fluorescent screen. This image is then viewed by a CCD camera and analyzed using a computer program to calculate the intensity centroid, the beam profile and integrated intensity. These data are delivered to the CHESS signal archiving system for storage and display. The new systems employ digital cameras. These cameras are free of the noise inherent to the analog systems with long video signal connections. As a result, the beam position data delivered by the new systems are more reliable and accurate as shown by beam position traces using different beam position monitors on the same beam line.

  18. New X-ray beam position monitors with submicron resolution utilizing imaging of scattered X-rays at CHESS

    Energy Technology Data Exchange (ETDEWEB)

    Revesz, Peter, E-mail: pr20@cornell.edu [Cornell University, Cornell High Energy Synchrotron Source, Ithaca 14850, NY (United States); Temnykh, Alexander B. [Cornell University, Laboratory for Elem-Particle Physics, Ithaca 14850, NY (United States); Pauling, Alan K. [Cornell University, Cornell High Energy Synchrotron Source, Ithaca 14850, NY (United States)

    2011-09-01

    At CHESS' A, F and G wiggler beam lines three new video beam position monitors (VBPMs) have been commissioned. These new VBPMs utilize X-rays scattered from the graphite filter (A and F line) or from a beryllium window (G-line) as the white wiggler beam passes through them. As the X-rays scatter in all directions from the scattering medium, a slit camera creates an image of the beam's footprint on a fluorescent screen. This image is then viewed by a CCD camera and analyzed using a computer program to calculate the intensity centroid, the beam profile and integrated intensity. These data are delivered to the CHESS signal archiving system for storage and display. The new systems employ digital cameras. These cameras are free of the noise inherent to the analog systems with long video signal connections. As a result, the beam position data delivered by the new systems are more reliable and accurate as shown by beam position traces using different beam position monitors on the same beam line.

  19. Monochromatic x-rays for low-dose digital mammography: preliminary results.

    Science.gov (United States)

    Yoon, Kwon-Ha; Kwon, Young Man; Choi, Byoung-Jung; Son, Hyun Hwa; Ryu, Cheol Woo; Chon, Kwon Su; Park, Seong Hoon; Juhng, Sun Kwan

    2012-12-01

    The feasibility of using monochromatic x-ray imaging generated from an x-ray tube and a multilayer reflector for digital mammography with a low radiation dose was examined. A multilayer mirror was designed to select the x-ray peak with an energy of 21.5 keV generated from an x-ray tube with a tungsten target and was fabricated by the ion-beam sputtering deposition system. Monochromatic x-ray images were obtained from an experimental digital mammography setup with a scanning stage. The performance of the system was evaluated using a breast phantom, a spectrometer, and a radiation dosimeter. We measured the contrast-to-noise ratio and performed the 10% modulation function test to determine image quality and resolution. The monochromatic beam from the multilayer reflector had a full-width-at-half-maximum of 0.9 keV at 21.5 keV, and the reflectivity was 0.70, which was 90% of the designed value. The polychromatic and monochromatic x-rays showed radiation doses of 0.497 and 0.0415 mGy, respectively. The monochromatic x-ray image shows fibers, calcifications, and masses more clearly than the polychromatic x-ray images do. The image contrast of the monochromatic x-rays was 1.85 times higher than that of the polychromatic x-rays. The experimental mammography setup had a spatial resolution of 7 lp/mm with both x-rays. Monochromatic x-rays generated using a multilayer mirror may be a useful diagnostic tool for breast examination by providing high contrast imaging with a low radiation dose.

  20. Quantification and normalization of x-ray mammograms

    International Nuclear Information System (INIS)

    Tromans, Christopher E; Cocker, Mary R; Brady, Michael

    2012-01-01

    The analysis of (x-ray) mammograms remains qualitative, relying on the judgement of clinicians. We present a novel method to compute a quantitative, normalized measure of tissue radiodensity traversed by the primary beam incident on each pixel of a mammogram, a measure we term the standard attenuation rate (SAR). SAR enables: the estimation of breast density which is linked to cancer risk; direct comparison between images; the full potential of computer aided diagnosis to be utilized; and a basis for digital breast tomosynthesis reconstruction. It does this by removing the effects of the imaging conditions under which the mammogram is acquired. First, the x-ray spectrum incident upon the breast is calculated, and from this, the energy exiting the breast is calculated. The contribution of scattered radiation is calculated and subtracted. The SAR measure is the scaling factor that must be applied to the reference material in order to match the primary attenuation of the breast. Specifically, this is the scaled reference material attenuation which when traversed by an identical beam to that traversing the breast, and when subsequently detected, results in the primary component of the pixel intensity observed in the breast image. We present results using two tissue equivalent phantoms, as well as a sensitivity analysis to detector response changes over time and possible errors in compressed thickness measurement. (paper)

  1. Differential diagnosis of benign and malignant breast tumors by high frequency molybdenum-target X-ray photography

    International Nuclear Information System (INIS)

    Mai Yuanqi; Wang Maosheng; Huang Jian; Cui Guoru; Liang Zhicong; Lu Yingying

    2008-01-01

    Objective: To explore the X-ray Image of benign and malignant breast lesions (tumors) in order to improve their differcatial diagnostic level. Methods: X-ray image changes of 63 malignant breast neoplasms were described by the mammography and in comparision with those of 43 benign masses. Results: The accordance percentages between the X-ray and histological examinations for the benign and malignant neoplasms were shown as 85% and 90.6% respectively. Spiculated mass, calcification granules in clusters and other images were found to be indication of benign or malignant breast lesion. Conclusion: The High Frequency Molybdenum-target X-ray Photography can provide effective imaging data for diagnosis and distinguish between the benign and malignant breast lesions. (authors)

  2. Using a tandem ionization chamber for quality control of X-ray beams

    International Nuclear Information System (INIS)

    Yoshizumi, Maira T.; Caldas, Linda V.E.

    2011-01-01

    X-ray beam qualities are defined by both the mean energies and by the half-value layers (HVL). Many international protocols use the half-value layer and the beam voltage to characterize the X-ray beam quality. A quality control program for X-ray equipment includes the constancy check of beam qualities, i.e., the periodical verification of the half-value layer, which can be a time consumable procedure. A tandem ionization chamber, developed at Instituto de Pesquisas Energeticas e Nucleares, was used to determine the HVL and its constancy for five radiotherapy standard beam qualities. This ionization chamber is composed by two sensitive volumes with inner electrodes made of different materials: aluminum and graphite. The beam quality constancy check test was performed during two months and the maximum variation obtained was 1.24% for the radiation beam quality T-10. This result is very satisfactory according to national recommendations. (author)

  3. Beam synchronous detection techniques for X-Ray spectroscopy

    International Nuclear Information System (INIS)

    Goujon, Gérard; Rogalev, Andreï; Goulon, José; Feite, Serge; Wilhelm, Fabrice

    2013-01-01

    The Photo diode detectors combine a set of properties that make them most appropriate, in particular, for X-ray Magnetic Circular Dichroism (XMCD) experiments. Under standard operating conditions, the detection bandwidth is primarily limited by the transimpedance preamplifier that converts the very low ac photocurrent into a voltage. On the other hand, when the photodiode is reverse biased, its finite shunt resistance will cause an undesirable, temperature dependent DC dark current. The best strategy to get rid of it is to use synchronous detection techniques. A classical implementation is based on the use of a chopper modulating the X-ray beam intensity at rather low frequencies (typically below 1 kHz). Here we report on the recent development of a fast Xray detection which has the capability to fully exploit the frequency structure of the ESRF X-ray beam (355 KHz and its harmonics). The availability of new wide band preamplifiers allowed us to extend the working frequency range up to a few MHz. A beam synchronous data processing was implemented in large FPGAs. Performances of the new detection system implemented at the ESRF beamline ID12 are illustrated with detection of the Fe K-edge XMCD spectra in garnets, using 4 bunches operation mode with modulation frequency of 1.4 MHz.

  4. Determination of the effective energy in X-rays standard beams, mammography level

    Energy Technology Data Exchange (ETDEWEB)

    Correa, Eduardo de Lima; Vivolo, Vitor; Potiens, Maria da Penha A., E-mail: Vivolo@ipen.b, E-mail: mppalbu@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The X-rays beams used in diagnostic radiology are heterogeneous. This means that, in a radiological beam, it can be found photons with different energies. Because of that is common to work with the concept of effective energy. In this study the effective energy of an X-rays system used in instruments calibration was determined, as part of the mammography radiation qualities establishment. The procedure presented here was developed based on information found in the literature. The X-ray mass attenuation coefficients for aluminum, given by NIST web site, were used and the mathematical adjusts were done using the Origin 8.0 program. The results are part of the mammographic X-rays beams characteristics determination and it is important to keep the quality of this reference system. (author)

  5. X-ray luminescence computed tomography imaging via multiple intensity weighted narrow beam irradiation

    Science.gov (United States)

    Feng, Bo; Gao, Feng; Zhao, Huijuan; Zhang, Limin; Li, Jiao; Zhou, Zhongxing

    2018-02-01

    The purpose of this work is to introduce and study a novel x-ray beam irradiation pattern for X-ray Luminescence Computed Tomography (XLCT), termed multiple intensity-weighted narrow-beam irradiation. The proposed XLCT imaging method is studied through simulations of x-ray and diffuse lights propagation. The emitted optical photons from X-ray excitable nanophosphors were collected by optical fiber bundles from the right-side surface of the phantom. The implementation of image reconstruction is based on the simulated measurements from 6 or 12 angular projections in terms of 3 or 5 x-ray beams scanning mode. The proposed XLCT imaging method is compared against the constant intensity weighted narrow-beam XLCT. From the reconstructed XLCT images, we found that the Dice similarity and quantitative ratio of targets have a certain degree of improvement. The results demonstrated that the proposed method can offer simultaneously high image quality and fast image acquisition.

  6. Dose properties of x-ray beams produced by laser-wakefield-accelerated electrons

    International Nuclear Information System (INIS)

    Kainz, K K; Hogstrom, K R; Antolak, J A; Almond, P R; Bloch, C D

    2005-01-01

    Given that laser wakefield acceleration (LWFA) has been demonstrated experimentally to accelerate electron beams to energies beyond 25 MeV, it is reasonable to assess the ability of existing LWFA technology to compete with conventional radiofrequency linear accelerators in producing electron and x-ray beams for external-beam radiotherapy. We present calculations of the dose distributions (off-axis dose profiles and central-axis depth dose) and dose rates of x-ray beams that can be produced from electron beams that are generated using state-of-the-art LWFA. Subsets of an LWFA electron energy distribution were propagated through the treatment head elements (presuming an existing design for an x-ray production target and flattening filter) implemented within the EGSnrc Monte Carlo code. Three x-ray energy configurations (6 MV, 10 MV and 18 MV) were studied, and the energy width ΔE of the electron-beam subsets varied from 0.5 MeV to 12.5 MeV. As ΔE increased from 0.5 MeV to 4.5 MeV, we found that the off-axis and central-axis dose profiles for x-rays were minimally affected (to within about 3%), a result slightly different from prior calculations of electron beams broadened by scattering foils. For ΔE of the order of 12 MeV, the effect on the off-axis profile was of the order of 10%, but the central-axis depth dose was affected by less than 2% for depths in excess of about 5 cm beyond d max . Although increasing ΔE beyond 6.5 MeV increased the dose rate at d max by more than 10 times, the absolute dose rates were about 3 orders of magnitude below those observed for LWFA-based electron beams at comparable energies. For a practical LWFA-based x-ray device, the beam current must be increased by about 4-5 orders of magnitude. (note)

  7. Using X-Ray Mammograms to Assist in Microwave Breast Image Interpretation

    Directory of Open Access Journals (Sweden)

    Charlotte Curtis

    2012-01-01

    Full Text Available Current clinical breast imaging modalities include ultrasound, magnetic resonance (MR imaging, and the ubiquitous X-ray mammography. Microwave imaging, which takes advantage of differing electromagnetic properties to obtain image contrast, shows potential as a complementary imaging technique. As an emerging modality, interpretation of 3D microwave images poses a significant challenge. MR images are often used to assist in this task, and X-ray mammograms are readily available. However, X-ray mammograms provide 2D images of a breast under compression, resulting in significant geometric distortion. This paper presents a method to estimate the 3D shape of the breast and locations of regions of interest from standard clinical mammograms. The technique was developed using MR images as the reference 3D shape with the future intention of using microwave images. Twelve breast shapes were estimated and compared to ground truth MR images, resulting in a skin surface estimation accurate to within an average Euclidean distance of 10 mm. The 3D locations of regions of interest were estimated to be within the same clinical area of the breast as corresponding regions seen on MR imaging. These results encourage investigation into the use of mammography as a source of information to assist with microwave image interpretation as well as validation of microwave imaging techniques.

  8. Soft X-ray beam induced current technique

    Energy Technology Data Exchange (ETDEWEB)

    Watts, B; Ade, H [Department of Physics, North Carolina State University, Raleigh, NC 27695 (United States); Queen, D; Hellman, F [Department of Physics, University of California, Berkeley, CA 94720 (United States); Kilcoyne, A L D; Tyliszczak, T, E-mail: benjamin.watts@gmail.co [Advanced Light Source, Lawrence Berkeley Nat. Lab., Berkeley, CA 94720 (United States)

    2009-09-01

    Direct mapping of the charge transport efficiency of polymer solar cell devices using a soft X-ray beam induced current (SoXBIC) method is described. By fabricating a polymer solar cell on an x-ray transparent substrate, we demonstrate the ability to map polymer composition and nanoscale structure within an operating solar cell device and to simultaneously measure the local charge transport efficiency via the short-circuit current. A simple model is calculated and compared to experimental SoXBIC data of a PFB:F8BT bulk-heterojunction device in order to gain greater insight into the device operation and physics.

  9. Comparison of neutron and high-energy X-ray dual-beam radiography for air cargo inspection

    International Nuclear Information System (INIS)

    Liu, Y.; Sowerby, B.D.; Tickner, J.R.

    2008-01-01

    Dual-beam radiography techniques utilising various combinations of high-energy X-rays and neutrons are attractive for screening bulk cargo for contraband such as narcotics and explosives. Dual-beam radiography is an important enhancement to conventional single-beam X-ray radiography systems in that it provides additional information on the composition of the object being imaged. By comparing the attenuations of transmitted dual high-energy beams, it is possible to build a 2D image, colour coded to indicate material. Only high-energy X-rays, gamma-rays and neutrons have the required penetration to screen cargo containers. This paper reviews recent developments and applications of dual-beam radiography for air cargo inspection. These developments include dual high-energy X-ray techniques as well as fast neutron and gamma-ray (or X-ray) radiography systems. High-energy X-ray systems have the advantage of generally better penetration than neutron systems, depending on the material being interrogated. However, neutron systems have the advantage of much better sensitivity to material composition compared to dual high-energy X-ray techniques. In particular, fast neutron radiography offers the potential to discriminate between various classes of organic material, unlike dual energy X-ray techniques that realistically only offer the ability to discriminate between organic and metal objects

  10. Highly porous nanoberyllium for X-ray beam speckle suppression

    Energy Technology Data Exchange (ETDEWEB)

    Goikhman, Alexander, E-mail: agoikhman@ymail.com; Lyatun, Ivan; Ershov, Petr [Immanuel Kant Baltic Federal University, Nevskogo str. 14, Kaliningrad 236041 (Russian Federation); Snigireva, Irina [European Synchrotron Radiation Facility, BP 220, 38043 Grenoble (France); Wojda, Pawel [Immanuel Kant Baltic Federal University, Nevskogo str. 14, Kaliningrad 236041 (Russian Federation); Gdańsk University of Technology, 11/12 G. Narutowicza, Gdańsk 80-233 (Poland); Gorlevsky, Vladimir; Semenov, Alexander; Sheverdyaev, Maksim; Koletskiy, Viktor [A. A. Bochvar High-Technology Scientific Research Institute for Inorganic Materials, Rogova str. 5a, Moscow 123098 (Russian Federation); Snigirev, Anatoly [Immanuel Kant Baltic Federal University, Nevskogo str. 14, Kaliningrad 236041 (Russian Federation); European Synchrotron Radiation Facility, BP 220, 38043 Grenoble (France)

    2015-04-09

    A speckle suppression device containing highly porous nanoberyllium is proposed for manipulating the spatial coherence length and removing undesirable speckle structure during imaging experiments. This paper reports a special device called a ‘speckle suppressor’, which contains a highly porous nanoberyllium plate squeezed between two beryllium windows. The insertion of the speckle suppressor in an X-ray beam allows manipulation of the spatial coherence length, thus changing the effective source size and removing the undesirable speckle structure in X-ray imaging experiments almost without beam attenuation. The absorption of the nanoberyllium plate is below 1% for 1 mm thickness at 12 keV. The speckle suppressor was tested on the ID06 ESRF beamline with X-rays in the energy range from 9 to 15 keV. It was applied for the transformation of the phase–amplitude contrast to the pure amplitude contrast in full-field microscopy.

  11. Highly porous nanoberyllium for X-ray beam speckle suppression

    International Nuclear Information System (INIS)

    Goikhman, Alexander; Lyatun, Ivan; Ershov, Petr; Snigireva, Irina; Wojda, Pawel; Gorlevsky, Vladimir; Semenov, Alexander; Sheverdyaev, Maksim; Koletskiy, Viktor; Snigirev, Anatoly

    2015-01-01

    A speckle suppression device containing highly porous nanoberyllium is proposed for manipulating the spatial coherence length and removing undesirable speckle structure during imaging experiments. This paper reports a special device called a ‘speckle suppressor’, which contains a highly porous nanoberyllium plate squeezed between two beryllium windows. The insertion of the speckle suppressor in an X-ray beam allows manipulation of the spatial coherence length, thus changing the effective source size and removing the undesirable speckle structure in X-ray imaging experiments almost without beam attenuation. The absorption of the nanoberyllium plate is below 1% for 1 mm thickness at 12 keV. The speckle suppressor was tested on the ID06 ESRF beamline with X-rays in the energy range from 9 to 15 keV. It was applied for the transformation of the phase–amplitude contrast to the pure amplitude contrast in full-field microscopy

  12. Cone Beam X-Ray Luminescence Tomography Imaging Based on KA-FEM Method for Small Animals.

    Science.gov (United States)

    Chen, Dongmei; Meng, Fanzhen; Zhao, Fengjun; Xu, Cao

    2016-01-01

    Cone beam X-ray luminescence tomography can realize fast X-ray luminescence tomography imaging with relatively low scanning time compared with narrow beam X-ray luminescence tomography. However, cone beam X-ray luminescence tomography suffers from an ill-posed reconstruction problem. First, the feasibility of experiments with different penetration and multispectra in small animal has been tested using nanophosphor material. Then, the hybrid reconstruction algorithm with KA-FEM method has been applied in cone beam X-ray luminescence tomography for small animals to overcome the ill-posed reconstruction problem, whose advantage and property have been demonstrated in fluorescence tomography imaging. The in vivo mouse experiment proved the feasibility of the proposed method.

  13. Thermoluminescence of zirconium oxide nanostructured to mammography X-ray beams

    International Nuclear Information System (INIS)

    Palacios, L.L.; Rivera, T.; Roman, J.; Azorín, J.; Gaona, E.

    2012-01-01

    In the present work thermoluminescent (TL) response of zirconium oxide (ZrO 2 ) nanostructured induced by mammography X-ray radiation was investigated. Measurements were made of the response per unit air kerma of ZrO 2 with mammography equipment parameters (semiautomatic exposure control, 24 kVp and 108 mAs). The calibration curves were obtained by simultaneously irradiating ZrO 2 samples and ion chamber. Samples of ZrO 2 showed a linear response as a function of entrance skin air kerma. The observed results in TL properties suggest that ZrO 2 nanostructured could be considered as an effective material for X-ray beams dosimetry if appropriate calibration procedures are performed. - Highlights: ► X-ray low energy thermoluminescent of ZrO 2 dosimeter is developed. ► Air kerma measurements were made by thermoluminescent dosimeter ZrO 2 using mammography equipment parameters. ► Entrance surface skin doses were made using thermoluminescent dosimeter of ZrO 2 to X-ray beam quality control.

  14. Development and commissioning of an x-ray beam alignment flag for NSLS-II

    Energy Technology Data Exchange (ETDEWEB)

    Kosciuk, B., E-mail: bkosciuk@bnl.gov; Hu, Y.; Keister, J.; Seletskiy, S. [National Synchrotron Light Source-II, Brookhaven National Laboratory, Upton, New York 11973 (United States)

    2016-07-27

    The NSLS-II Synchrotron Light Source is a 3 GeV electron storage ring recently commissioned and is now entering operations at Brookhaven National Laboratory. One of the major tasks was to commission the six project beamline front ends which required a diagnostic to resolve x-ray beam position for the purpose of beam alignment at low current. Since none of the front ends were outfitted with any x-ray diagnostics in the baseline design, an x-ray beam profile monitor or “flag” that could be easily installed into existing front end vacuum chambers was proposed to satisfy this requirement. Here we present the development of this novel device which utilizes a polycrystalline CVD diamond luminescent screen to produce a visible image of the x-ray beam cross-section and is then captured with a CCD camera.

  15. Micro-beam X-ray fluorescence and absorption imaging techniques at the IAEA Laboratories

    International Nuclear Information System (INIS)

    Wegrzynek, Dariusz; Markowicz, A.; Bamford, S.; Chinea-Cano, E.; Bogovac, M.

    2005-01-01

    X-ray tube based, micro-beam X-ray fluorescence scanning spectrometer has been equipped with two energy dispersive X-ray detectors. The two-detector configuration allows for simultaneous collection of X-ray fluorescence (XRF) and transmitted X-ray beam signals with a spatial resolution in the range of 10-50 μm, depending on the X-ray focussing element in use. The XRF signal is collected with a standard, liquid nitrogen cooled Si(Li) detector. The X-ray beam transmitted through the sample is acquired with a thermoelectrically cooled, silicon drift (SD) detector. The data acquisition is carried out in a fully automatic way under control of the SPECTOR-LOCATOR software. The software controls the scanning procedure and X-ray spectra acquisition during the scan. The energy dispersive X-ray spectra collected at every 'pixel' are stored for off-line processing. For selected regions of interest (ROI's), the element maps are constructed and displayed on-line. The spectrometer has been used for mapping elemental distributions and for performing 2D- and 3D-tomograpic imaging of minute objects in X-ray absorption and in X-ray fluorescence mode. A unique feature of the described system is simultaneous utilization of the two detectors, Si(Li) and SD, which adds new options for quantitative analysis and data interpretation. Examples of elemental mapping and 3D tomographic imaging as well as the advanced features of the SPECTOR-LOCATOR measurement control and data acquisition software are presented in this work

  16. Characterization and control of femtosecond electron and X-ray beams at free-electron lasers

    International Nuclear Information System (INIS)

    Behrens, Christopher

    2012-11-01

    X-ray free-electron lasers (FELs) open up new frontiers in photon science, and in order to take full advantage of these unique accelerator-based light sources, the characterization and control of the femtosecond electron and X-ray beams is essential. Within this cumulative thesis, recent results achieved within the active research field of femtosecond electron and X-ray beams at FELs are reported.The basic principles of X-ray FELs are described, and concepts of longitudinal electron beam diagnostics with femtosecond accuracy are covered. Experimental results obtained with a transverse deflecting structure (TDS) and spectroscopy of coherent terahertz radiation are presented, and the suppression of coherent optical radiation effects, required for diagnostics utilizing a TDS, is demonstrated. Control of the longitudinal phase space by using multiple radio frequencies for longitudinal electron beam tailoring is presented, and a new technique of reversible electron beam heating with two TDSs is described. For the characterization of femtosecond X-ray pulses, a novel method based on dedicated longitudinal phase space diagnostics for electron beams is introduced, and recent measurements with a streaking technique using external terahertz fields are presented.

  17. Characterization and control of femtosecond electron and X-ray beams at free-electron lasers

    Energy Technology Data Exchange (ETDEWEB)

    Behrens, Christopher

    2012-11-15

    X-ray free-electron lasers (FELs) open up new frontiers in photon science, and in order to take full advantage of these unique accelerator-based light sources, the characterization and control of the femtosecond electron and X-ray beams is essential. Within this cumulative thesis, recent results achieved within the active research field of femtosecond electron and X-ray beams at FELs are reported.The basic principles of X-ray FELs are described, and concepts of longitudinal electron beam diagnostics with femtosecond accuracy are covered. Experimental results obtained with a transverse deflecting structure (TDS) and spectroscopy of coherent terahertz radiation are presented, and the suppression of coherent optical radiation effects, required for diagnostics utilizing a TDS, is demonstrated. Control of the longitudinal phase space by using multiple radio frequencies for longitudinal electron beam tailoring is presented, and a new technique of reversible electron beam heating with two TDSs is described. For the characterization of femtosecond X-ray pulses, a novel method based on dedicated longitudinal phase space diagnostics for electron beams is introduced, and recent measurements with a streaking technique using external terahertz fields are presented.

  18. A new high-speed X-ray beam chopper

    International Nuclear Information System (INIS)

    McPherson, A.; Wang, J.; Lee, P. L.; Mills, D. M.

    1999-01-01

    A new high-speed x-ray beam chopper using laser scanner technology has been developed and tested on the SRI-CAT sector 1 beamline at the Advanced Photon Source (APS) storage ring (1). As illustrated in figure 1, it is compact in size and has two sets of transmission windows: BK-7 glass for visible light transmission and 0.23-mm-thick Be for the transmission of x-rays. The rotor is made of aluminum and has a diameter of 50.8 mm. A 0.5-mm-wide and 2.29-mm-tall slit is cut through the center of the rotor. The circumference of the rotor has a coating of 1-mm-thick Ni, which gives an attenuation of 10 8 at 30 keV. Turning at nearly 80000 RPM, this beam chopper has an opening time window of 2450 ns, corresponding to 67% of the revolution time of the APS storage ring. The primary feature in selecting laser scanner technology to develop into an x-ray beam chopper was the high level of rotational speed control of the rotor that makes up the beam chopper element (2). By using an optical feedback circuit to sample the rotational speed four times each revolution, the jitter in the position of the transmission open time window is only 3 ns at the 3 standard deviation level. The APS storage ring orbital frequency, supplied by the control room, is divided down to provide the appropriate drive frequency for the beam chopper motor controller. By this means, both the storage ring and the beam chopper are operating off the same master clock. After a turn-on time of about 15 to 20 seconds, the rotational precision of the motor results in immediate phase locking to the temporal structure of the APS storage ring. By inserting a Stanford delay generator between the frequency divider and the beam chopper motor controller, the phase between the storage ring temporal structure and the beam chopper rotation can be adjusted to position the transmission time window of the beam chopper on any desired part of the storage ring fill pattern. If an asymmetric fill pattern is used in the APS storage

  19. Thermoluminescence of zirconium oxide nanostructured to mammography X-ray beams

    Energy Technology Data Exchange (ETDEWEB)

    Palacios, L.L. [Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada-Legaria, IPN. Av. Legaria 694, 11500 Mexico D.F. (Mexico); Rivera, T., E-mail: trivera@ipn.mx [Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada-Legaria, IPN. Av. Legaria 694, 11500 Mexico D.F. (Mexico); Roman, J. [Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada-Legaria, IPN. Av. Legaria 694, 11500 Mexico D.F. (Mexico); Azorin, J. [Universidad Autonoma Metropolitana-Iztapalapa. Av. San Rafael Atlixco 187, 09340 Mexico D.F. (Mexico); Gaona, E. [Universidad Autonoma Metropolitana-Xochimilco. Calz. Del Hueso 1100, 04960 Mexico D.F. (Mexico)

    2012-07-15

    In the present work thermoluminescent (TL) response of zirconium oxide (ZrO{sub 2}) nanostructured induced by mammography X-ray radiation was investigated. Measurements were made of the response per unit air kerma of ZrO{sub 2} with mammography equipment parameters (semiautomatic exposure control, 24 kVp and 108 mAs). The calibration curves were obtained by simultaneously irradiating ZrO{sub 2} samples and ion chamber. Samples of ZrO{sub 2} showed a linear response as a function of entrance skin air kerma. The observed results in TL properties suggest that ZrO{sub 2} nanostructured could be considered as an effective material for X-ray beams dosimetry if appropriate calibration procedures are performed. - Highlights: Black-Right-Pointing-Pointer X-ray low energy thermoluminescent of ZrO{sub 2} dosimeter is developed. Black-Right-Pointing-Pointer Air kerma measurements were made by thermoluminescent dosimeter ZrO{sub 2} using mammography equipment parameters. Black-Right-Pointing-Pointer Entrance surface skin doses were made using thermoluminescent dosimeter of ZrO{sub 2} to X-ray beam quality control.

  20. X-ray pencil beam facility for optics characterization

    Science.gov (United States)

    Krumrey, Michael; Cibik, Levent; Müller, Peter; Bavdaz, Marcos; Wille, Eric; Ackermann, Marcelo; Collon, Maximilien J.

    2010-07-01

    The Physikalisch-Technische Bundesanstalt (PTB) has used synchrotron radiation for the characterization of optics and detectors for astrophysical X-ray telescopes for more than 20 years. At a dedicated beamline at BESSY II, a monochromatic pencil beam is used by ESA and cosine Research since the end of 2005 for the characterization of novel silicon pore optics, currently under development for the International X-ray Observatory (IXO). At this beamline, a photon energy of 2.8 keV is selected by a Si channel-cut monochromator. Two apertures at distances of 12.2 m and 30.5 m from the dipole source form a pencil beam with a typical diameter of 100 μm and a divergence below 1". The optics to be investigated is placed in a vacuum chamber on a hexapod, the angular positioning is controlled by means of autocollimators to below 1". The reflected beam is registered at 5 m distance from the optics with a CCD-based camera system. This contribution presents design and performance of the upgrade of this beamline to cope with the updated design for IXO. The distance between optics and detector can now be 20 m. For double reflection from an X-ray Optical Unit (XOU) and incidence angles up to 1.4°, this corresponds to a vertical translation of the camera by 2 m. To achieve high reflectance at this angle even with uncoated silicon, a lower photon energy of 1 keV is available from a pair of W/B4C multilayers. For coated optics, a high energy option can provide a pencil beam of 7.6 keV radiation.

  1. A water-cooled x-ray monochromator for using off-axis undulator beam

    International Nuclear Information System (INIS)

    Khounsary, A.; Maser, J.

    2000-01-01

    Undulator beamlines at third-generation synchrotrons x-ray sources are designed to use the high-brilliance radiation that is contained in the central cone of the generated x-ray beams. The rest of the x-ray beam is often unused. Moreover, in some cases, such as in the zone-plate-based microfocusing beamlines, only a small part of the central radiation cone around the optical axis is used. In this paper, a side-station branch line at the Advanced Photon Source that takes advantage of some of the unused off-axis photons in a microfocusing x-ray beamline is described. Detailed information on the design and analysis of a high-heat-load water-cooled monochromator developed for this beamline is provided

  2. Investigation of chemical vapour deposition diamond detectors by X-ray micro-beam induced current and X-ray micro-beam induced luminescence techniques

    International Nuclear Information System (INIS)

    Olivero, P.; Manfredotti, C.; Vittone, E.; Fizzotti, F.; Paolini, C.; Lo Giudice, A.; Barrett, R.; Tucoulou, R.

    2004-01-01

    Tracking detectors have become an important ingredient in high-energy physics experiments. In order to survive the harsh detection environment of the large hadron collider (LHC), trackers need to have special properties. They must be radiation hard, provide fast collection of charge, be as thin as possible and remove heat from readout electronics. The unique properties of diamond allow it to fulfill these requirements. In this work we present an investigation of the charge transport and luminescence properties of 'detector grade' artificial chemical vapour deposition (CVD) diamond devices developed within the CERN RD42 collaboration, performed by means of X-ray micro-beam induced current collection (XBICC) and X-ray micro-beam induced luminescence (XBIL) techniques. XBICC technique allows quantitative estimates of the transport parameters of the material to be evaluated and mapped with micrometric spatial resolution. In particular, the high resolution and sensitivity of the technique has allowed a quantitative study of the inhomogeneity of the charge transport parameter defined as the product of mobility and lifetime for both electron and holes. XBIL represents a technique complementary to ion beam induced luminescence (IBIL), which has already been used by our group, since X-ray energy loss profile in the material is different from that of MeV ions. X-ray induced luminescence maps have been performed simultaneously with induced photocurrent maps, to correlate charge transport and induced luminescence properties of diamond. Simultaneous XBICC and XBIL maps exhibit features of partial complementarity that have been interpreted on the basis of considerations on radiative and non-radiative recombination processes which compete with charge transport efficiency

  3. X-ray scatter correction method for dedicated breast computed tomography: improvements and initial patient testing

    International Nuclear Information System (INIS)

    Ramamurthy, Senthil; D’Orsi, Carl J; Sechopoulos, Ioannis

    2016-01-01

    A previously proposed x-ray scatter correction method for dedicated breast computed tomography was further developed and implemented so as to allow for initial patient testing. The method involves the acquisition of a complete second set of breast CT projections covering 360° with a perforated tungsten plate in the path of the x-ray beam. To make patient testing feasible, a wirelessly controlled electronic positioner for the tungsten plate was designed and added to a breast CT system. Other improvements to the algorithm were implemented, including automated exclusion of non-valid primary estimate points and the use of a different approximation method to estimate the full scatter signal. To evaluate the effectiveness of the algorithm, evaluation of the resulting image quality was performed with a breast phantom and with nine patient images. The improvements in the algorithm resulted in the avoidance of introduction of artifacts, especially at the object borders, which was an issue in the previous implementation in some cases. Both contrast, in terms of signal difference and signal difference-to-noise ratio were improved with the proposed method, as opposed to with the correction algorithm incorporated in the system, which does not recover contrast. Patient image evaluation also showed enhanced contrast, better cupping correction, and more consistent voxel values for the different tissues. The algorithm also reduces artifacts present in reconstructions of non-regularly shaped breasts. With the implemented hardware and software improvements, the proposed method can be reliably used during patient breast CT imaging, resulting in improvement of image quality, no introduction of artifacts, and in some cases reduction of artifacts already present. The impact of the algorithm on actual clinical performance for detection, diagnosis and other clinical tasks in breast imaging remains to be evaluated. (paper)

  4. The histories of capillary optics for x-rays and ion beams in Russia, USA, and Japan

    International Nuclear Information System (INIS)

    Umezawa, Kenji

    2009-01-01

    This article introduces the history of X-ray lens and the present situation of ion beam focusing with glass capillaries systems. The basic technology of X-ray lens using glass capillaries was independently developed over 20 years by Prof. Kumakhov in the former Soviet Union and Dr. Soejima in Japan, respectively. In the 1990's, Prof. W.M. Gibson and his coworkers intensively studied X-rays and neutron optics in Albany, NY, USA. X-ray optics with glass capillaries, in these days is well known in the world. This unique technique was fabricated to collimate X-rays. Also, new ion beam analysis technique with glass capillaries systems has been intensively developed by Dr. Nebiki and Prof. Narusawa in Kochi, Japan. These X-rays and ion beams techniques have brought new application for many fields; X-ray detector, X-ray lithography, X-ray astronomy, microdiffraction, medical therapy and biological applications. (author)

  5. Cone Beam X-ray Luminescence Computed Tomography Based on Bayesian Method.

    Science.gov (United States)

    Zhang, Guanglei; Liu, Fei; Liu, Jie; Luo, Jianwen; Xie, Yaoqin; Bai, Jing; Xing, Lei

    2017-01-01

    X-ray luminescence computed tomography (XLCT), which aims to achieve molecular and functional imaging by X-rays, has recently been proposed as a new imaging modality. Combining the principles of X-ray excitation of luminescence-based probes and optical signal detection, XLCT naturally fuses functional and anatomical images and provides complementary information for a wide range of applications in biomedical research. In order to improve the data acquisition efficiency of previously developed narrow-beam XLCT, a cone beam XLCT (CB-XLCT) mode is adopted here to take advantage of the useful geometric features of cone beam excitation. Practically, a major hurdle in using cone beam X-ray for XLCT is that the inverse problem here is seriously ill-conditioned, hindering us to achieve good image quality. In this paper, we propose a novel Bayesian method to tackle the bottleneck in CB-XLCT reconstruction. The method utilizes a local regularization strategy based on Gaussian Markov random field to mitigate the ill-conditioness of CB-XLCT. An alternating optimization scheme is then used to automatically calculate all the unknown hyperparameters while an iterative coordinate descent algorithm is adopted to reconstruct the image with a voxel-based closed-form solution. Results of numerical simulations and mouse experiments show that the self-adaptive Bayesian method significantly improves the CB-XLCT image quality as compared with conventional methods.

  6. Computed tomography for light materials using a monochromatic X-ray beam produced by parametric X-ray radiation

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, Y., E-mail: yahayak@lebra.nihon-u.ac.jp [Laboratory for Electron Beam Research and Application, Nihon University, Narashinodai 7-24-1, Funabashi 274-8501 (Japan); Hayakawa, K.; Inagaki, M. [Laboratory for Electron Beam Research and Application, Nihon University, Narashinodai 7-24-1, Funabashi 274-8501 (Japan); Kaneda, T. [Nihon University School of Dentistry at Matsudo, Sakaecho-Nishi 2-870-1, Matsudo 271-8587 (Japan); Nakao, K.; Nogami, K. [Laboratory for Electron Beam Research and Application, Nihon University, Narashinodai 7-24-1, Funabashi 274-8501 (Japan); Sakae, T. [Nihon University School of Dentistry at Matsudo, Sakaecho-Nishi 2-870-1, Matsudo 271-8587 (Japan); Sakai, T.; Sato, I. [Laboratory for Electron Beam Research and Application, Nihon University, Narashinodai 7-24-1, Funabashi 274-8501 (Japan); Takahashi, Y. [Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Oho, Tsukuba 305-8501 (Japan); Tanaka, T. [Laboratory for Electron Beam Research and Application, Nihon University, Narashinodai 7-24-1, Funabashi 274-8501 (Japan)

    2013-08-15

    Computed tomography (CT) for light materials such as soft biological tissues was performed using a monochromatic X-ray beam provided by a parametric X-ray radiation (PXR) source at the Laboratory for Electron Beam Research and Application (LEBRA) of Nihon University. Using a high-efficiency flat panel detector (FPD), each projection image for CT was taken with exposure times of 5 or 10 s, and 60–360 projection images in each run were obtained with total measurement time of 5 min to 1 h. CT images were obtained from the projection images using the conventional calculation method. The typical tomograms obtained had sharp outlines, which are likely attributable to the propagation-based phase contrast.

  7. Study on Compression Induced Contrast in X-ray Mammograms Using Breast Mimicking Phantoms

    Directory of Open Access Journals (Sweden)

    A. B. M. Aowlad Hossain

    2015-09-01

    Full Text Available X-ray mammography is commonly used to scan cancer or tumors in breast using low dose x-rays. But mammograms suffer from low contrast problem. The breast is compressed in mammography to reduce x-ray scattering effects. As tumors are stiffer than normal tissues, they undergo smaller deformation under compression. Therefore, image intensity at tumor region may change less than the background tissues. In this study, we try to find out compression induced contrast from multiple mammographic images of tumorous breast phantoms taken with different compressions. This is an extended work of our previous simulation study with experiment and more analysis. We have used FEM models for synthetic phantom and constructed a phantom using agar and n-propanol for simulation and experiment. The x-ray images of deformed phantoms have been obtained under three compression steps and a non-rigid registration technique has been applied to register these images. It is noticeably observed that the image intensity changes at tumor are less than those at surrounding which induce a detectable contrast. Addition of this compression induced contrast to the simulated and experimental images has improved their original contrast by a factor of about 1.4

  8. Ion beam induced surface graphitization of CVD diamond for x-ray beam position monitor applications

    International Nuclear Information System (INIS)

    Liu, Chian; Shu, D.; Kuzay, T.M.; Wen, L.; Melendres, C.A.; Argonne National Lab., IL

    1996-01-01

    The Advanced Photon Source at ANL is a third-generation synchrotron facility that generates powerful x-ray beams on its undulator beamlines. It is important to know the position and angle of the x- ray beam during experiments. Due to very high heat flux levels, several patented x-ray beam position monitors (XBPM) exploiting chemical vapor deposition (CVD) diamond have been developed. These XBPMs have a thin layer of low-atomic-mass metallic coating so that photoemission from the x rays generate a minute but measurable current for position determination. Graphitization of the CVD diamond surface creates a very thin, intrinsic and conducting layer that can stand much higher temperatures and minimal x-ray transmission losses compared to the coated metallic layers. In this paper, a laboratory sputter ion source was used to transform selected surfaces of a CVD diamond substrate into graphite. The effect of 1-5 keV argon ion bombardment on CVD diamond surfaces at various target temperatures from 200 to 500 C was studied using Auger electron spectroscopy and in-situ electrical resistivity measurements. Graphitization after the ion bombardment has been confirmed and optimum conditions for graphitization studied. Raman spectroscopy was used to identify the overall diamond structure in the bulk of CVD diamond substrate after the ion bombardments. It was found that target temperature plays an important role in stability and electrical conductivity of the irradiated CVD diamonds

  9. Breast neoplasms in women treated with x-rays for acute postpartum mastitis

    International Nuclear Information System (INIS)

    Shore, R.E.; Hempelmann, L.H.; Kowaluk, E.; Mansur, P.S.; Pasternack, B.S.; Albert, R.E.; Haughie, G.E.

    1977-01-01

    Breast cancer has been studied by mail survey up to 34 years in 571 of 606 women treated with x-rays for acute postpartum mastitis. The incidence of neoplasms was compared with that of three nonirradiated control groups--nonirradiated sisters of the treated women, women with acute postpartum mastitis not treated with X-rays, and their nonirradiated sisters. For the irradiated group, with a mean dose of 247 rads to both breasts, the overall relative risk of breast cancer was 2.2 for years 10 to 34 post irradiation and 3.6 for 20 to 34. The dose response for malignant and benign breast neoplasms was compatible with a linear fit. For comparable total doses, fractionation of exposure did not reduce carcinogenic action. Women over age 30 years at radiation treatment had as great an excess risk of breast cancer as did younger women. The overall excess risk of developing breast cancer was about 8 to 10 cases per million women per rad per year, an increase of about 0.5% per rad

  10. X-ray convergent beam pattern simulation using the Moodie-Wagenfeld equations: 3-beam Laue case

    International Nuclear Information System (INIS)

    Liu, L.; Goodman, P.

    1998-01-01

    Pattern simulations for 3-beam X-ray diffraction are presented, by multi-slice calculations based on Moodie and Wagenfeld's formulation of the X-ray equations, which factorise Maxwell's equations into Dirac format, using circular-polarisation bases. The results are presented in the form of convergent-beam patterns for each diffraction order, using experience gained from CBED (convergent beam electron diffraction) and LACBED (large-angle CBED), since this displays the results in the most compact form. The acronym CBXRAD (convergent-beam X-ray-diffraction) is used for these patterns. Although optics required for the complete patterns is not currently available, capillary focussing is undergoing rapid development, and our simulations define critical angular ranges within reach of current designs. Simulations for light and heavy-atoms structures belonging to the enantiomorphic space-group pair P3 1 21 and P3 2 21, provide clear evidence of chiral interaction between radiation and structure, highlighting divergences from the well studied CBED pattern symmetries. MoKα 1 and TaKα 1 wavelengths were used to minimise absorption for the two structures respectively, although 'anomalous absorption' is always important due to the large thicknesses required (up to 20 mm)

  11. Diamond monochromator for high heat flux synchrotron x-ray beams

    International Nuclear Information System (INIS)

    Khounsary, A.M.; Smither, R.K.; Davey, S.; Purohit, A.

    1992-12-01

    Single crystal silicon has been the material of choice for x-ray monochromators for the past several decades. However, the need for suitable monochromators to handle the high heat load of the next generation synchrotron x-ray beams on the one hand and the rapid and on-going advances in synthetic diamond technology on the other make a compelling case for the consideration of a diamond mollochromator system. In this Paper, we consider various aspects, advantage and disadvantages, and promises and pitfalls of such a system and evaluate the comparative an monochromator subjected to the high heat load of the most powerful x-ray beam that will become available in the next few years. The results of experiments performed to evaluate the diffraction properties of a currently available synthetic single crystal diamond are also presented. Fabrication of diamond-based monochromator is within present technical means

  12. Evaluation of mammographic X-ray beams using a phosphor plate

    Energy Technology Data Exchange (ETDEWEB)

    Bustos F, M.; Prata M, A., E-mail: mbustos@ufmg.br [Universidade Federal de Minas Gerais, Departamento de Engenharia Nuclear, Av. Pte. Antonio Carlos 6627, 31270-901 Pampulha, Belo Horizonte, Minas Gerais (Brazil)

    2016-10-15

    Currently, breast cancer is the second type of cancer more with higher overall incidence recorded in 2015, more than 57,000 new cases according to the National Cancer Institute of Brazil Mammography is now one of the imaging technique most widely used worldwide for the early diagnosis of breast cancer. The computed radiography (Cr) plates are used to obtain digital radiographs, and are widely used for digital mammogram production. This study aims to evaluate the variation response in the exposure of a Cr plate in mammography unit. For this study a mammography device model Graph A F Mammo, made by Vmi and a Cr plate, model Regius, were used for mammography. Experiments were made with two X-ray beams of 20 and 25 kV. Successive exposures of the Cr plate were made in a time range time from 0.5 to 2.5 s., to obtain unprocessed images .raw and subsequently make the measurement of time, air kerma and air kerma rate using a Ray Safe Xi meter. Five measurements for each exposure time were performed and the images were analyzed using the Image J software. A matrix of 21 x 21 pixels was selected in the central region of each image to obtain the intensity value, in grey scale, for each exposure time. From these data, a correlation of the degree of darkening was made with time and the air kerma. The behavior of the curves corresponding to the intensity average values of central pixels in relation to the exposure time and air kerma are similar for both voltages,showing an initially linear behavior and then a plate saturation region, whichever occurs first at the greatest value of the applied voltage. (Author)

  13. Evaluation of mammographic X-ray beams using a phosphor plate

    International Nuclear Information System (INIS)

    Bustos F, M.; Prata M, A.

    2016-10-01

    Currently, breast cancer is the second type of cancer more with higher overall incidence recorded in 2015, more than 57,000 new cases according to the National Cancer Institute of Brazil Mammography is now one of the imaging technique most widely used worldwide for the early diagnosis of breast cancer. The computed radiography (Cr) plates are used to obtain digital radiographs, and are widely used for digital mammogram production. This study aims to evaluate the variation response in the exposure of a Cr plate in mammography unit. For this study a mammography device model Graph A F Mammo, made by Vmi and a Cr plate, model Regius, were used for mammography. Experiments were made with two X-ray beams of 20 and 25 kV. Successive exposures of the Cr plate were made in a time range time from 0.5 to 2.5 s., to obtain unprocessed images .raw and subsequently make the measurement of time, air kerma and air kerma rate using a Ray Safe Xi meter. Five measurements for each exposure time were performed and the images were analyzed using the Image J software. A matrix of 21 x 21 pixels was selected in the central region of each image to obtain the intensity value, in grey scale, for each exposure time. From these data, a correlation of the degree of darkening was made with time and the air kerma. The behavior of the curves corresponding to the intensity average values of central pixels in relation to the exposure time and air kerma are similar for both voltages,showing an initially linear behavior and then a plate saturation region, whichever occurs first at the greatest value of the applied voltage. (Author)

  14. On the response of electronic personal dosimeters in constant potential and pulsed X-ray beams

    Energy Technology Data Exchange (ETDEWEB)

    Guimaraes, Margarete C.; Silva, Teogenes; Silva, Claudete R.E., E-mail: margaretecristinag@gmail.com [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Oliveira, Paulo Marcio C. de [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Anatomia e Imagem

    2015-07-01

    Electronic personal dosimeters (EPDs) based on solid state detectors have widely been used but some deficiencies in their response in pulsed radiation beams have been reported. Nowadays, there is not an international standard for pulsed X-ray beams for calibration or type testing of dosimeters. Irradiation conditions for testing the response of EPDs in both the constant potential and pulsed X-ray beams were established in CDTN. Three different types of EPDs were tested in different conditions in similar ISO and IEC X-ray qualities. Results stressed the need of performing additional checks before using EPDs in constant potential or pulsed X-rays. (author)

  15. Scanning-beam digital x-ray (SBDX) technology for interventional and diagnostic cardiac angiography

    International Nuclear Information System (INIS)

    Speidel, Michael A.; Wilfley, Brian P.; Star-Lack, Josh M.; Heanue, Joseph A.; Van Lysel, Michael S.

    2006-01-01

    The scanning-beam digital x-ray (SBDX) system is designed for x-ray dose reduction in cardiac angiographic applications. Scatter reduction, efficient detection of primary x-rays, and an inverse beam geometry are the main components of the entrance dose reduction strategy. This paper reports the construction of an SBDX prototype, image reconstruction techniques, and measurements of spatial resolution and x-ray output. The x-ray source has a focal spot that is electronically scanned across a large-area transmission target. A multihole collimator beyond the target defines a series of x-ray beams directed at a distant small-area detector array. The prototype has a 23 cmx23 cm target, 100x100 focal spot positions, and a 5 cmx5 cm CdTe detector positioned 150 cm from the target. With this nonmechanical method of beam scanning, patient images with low detected scatter are generated at up to 30 frame/s. SBDX data acquisition is tomosynthetic. The prototype simultaneously reconstructs 16 planes spaced throughout the cardiac volume using shift-and-add backprojection. Image frames analogous to conventional projection images are generated with a multiplane compositing algorithm. Single-plane versus multiplane reconstruction of contrast-filled coronary arteries is demonstrated with images of the porcine heart. Phantom and porcine imaging studies show multiplane reconstruction is practicable under clinically realistic levels of patient attenuation and cardiac motion. The modulation transfer function for an in-plane slit at mechanical isocenter measured 0.41-0.56 at 1 cycle/mm, depending on the detector element to image pixel interpolation technique. Modeling indicates that desired gains in spatial resolution are achievable by halving the detector element width. The x-ray exposure rate 15 cm below isocenter, without table or patient in the beam, measured 11.5 R/min at 120 kVp, 24.3 kWp and 3.42 R/min at 70 kVp, 14.2 kWp

  16. Scattered hard X-ray and γ-ray generation from a chromatic electron beam

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, J. E. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Welch, D. R.; Miller, C. L. [Voss Scientific, Albuquerque, New Mexico 87108 (United States)

    2015-11-14

    An array of photon diagnostics has been deployed on a high power relativistic electron beam diode. Electrons are extracted through a 17.8 cm diode from the surface discharge of a carbon fiber velvet cathode with a nominal diode voltage of 3.8 MV. <10% of the 100 ns electron pulse is composed of off energy electrons (1–3 MeV) accelerated during the rise and fall of the pulse that impact the stainless steel beam pipe and generate a Bremsstrahlung spectrum of 0.1–3 MeV photons with a total count of 10{sup 11}. The principal objective of these experiments is to quantify the electron beam dynamics and spatial dynamics of the hard X-ray and γ-ray flux generated in the diode region. A qualitative comparison of experimental and calculated results are presented, including time and energy resolved electron beam propagation and scattered photon measurements with X-ray PIN diodes and a photomultiplier tube indicating a dose dependence on the diode voltage >V{sup 4} and detected photon counts of nearly 10{sup 6} at a radial distance of 1 m which corresponds to dose ∼40 μrad at 1 m.

  17. Broad beam X-rays attenuation in silicum glass

    International Nuclear Information System (INIS)

    Risticj, Dj.; Vukovicj, S.; Markovicj, P.

    1987-01-01

    Using broad beam geometry the attenuation for domestic silicum glass have been studied for constant X-ray potentials from 50 to 150 kV. The density of the silicium glass was 2,5x10 3 kg/m 3 . From the attenuation curves the half value layers were obtained. The use of this glass as the biological shield is pointed out. (author). 2 refs.; 2 tabs.; 2 figs

  18. A preliminary study of breast cancer diagnosis using laboratory based small angle x-ray scattering

    Science.gov (United States)

    Round, A. R.; Wilkinson, S. J.; Hall, C. J.; Rogers, K. D.; Glatter, O.; Wess, T.; Ellis, I. O.

    2005-09-01

    Breast tissue collected from tumour samples and normal tissue from bi-lateral mastectomy procedures were examined using small angle x-ray scattering. Previous work has indicated that breast tissue disease diagnosis could be performed using small angle x-ray scattering (SAXS) from a synchrotron radiation source. The technique would be more useful to health services if it could be made to work using a conventional x-ray source. Consistent and reliable differences in x-ray scatter distributions were observed between samples from normal and tumour tissue samples using the laboratory based 'SAXSess' system. Albeit from a small number of samples, a sensitivity of 100% was obtained. This result encourages us to pursue the implementation of SAXS as a laboratory based diagnosis technique.

  19. A preliminary study of breast cancer diagnosis using laboratory based small angle x-ray scattering

    Energy Technology Data Exchange (ETDEWEB)

    Round, A R [Daresbury Laboratories, Warrington, WA4 4AD (United Kingdom); Wilkinson, S J [Daresbury Laboratories, Warrington, WA4 4AD (United Kingdom); Hall, C J [Daresbury Laboratories, Warrington, WA4 4AD (United Kingdom); Rogers, K D [Department of Materials and Medical Sciences, Cranfield University, Swindon, SN6 8LA (United Kingdom); Glatter, O [Department of Chemistry, University of Graz (Austria); Wess, T [School of Optometry and Vision Sciences, Cardiff University, Cardiff CF10 3NB, Wales (United Kingdom); Ellis, I O [Nottingham City Hospital, Nottingham (United Kingdom)

    2005-09-07

    Breast tissue collected from tumour samples and normal tissue from bi-lateral mastectomy procedures were examined using small angle x-ray scattering. Previous work has indicated that breast tissue disease diagnosis could be performed using small angle x-ray scattering (SAXS) from a synchrotron radiation source. The technique would be more useful to health services if it could be made to work using a conventional x-ray source. Consistent and reliable differences in x-ray scatter distributions were observed between samples from normal and tumour tissue samples using the laboratory based 'SAXSess' system. Albeit from a small number of samples, a sensitivity of 100% was obtained. This result encourages us to pursue the implementation of SAXS as a laboratory based diagnosis technique.

  20. A preliminary study of breast cancer diagnosis using laboratory based small angle x-ray scattering

    International Nuclear Information System (INIS)

    Round, A R; Wilkinson, S J; Hall, C J; Rogers, K D; Glatter, O; Wess, T; Ellis, I O

    2005-01-01

    Breast tissue collected from tumour samples and normal tissue from bi-lateral mastectomy procedures were examined using small angle x-ray scattering. Previous work has indicated that breast tissue disease diagnosis could be performed using small angle x-ray scattering (SAXS) from a synchrotron radiation source. The technique would be more useful to health services if it could be made to work using a conventional x-ray source. Consistent and reliable differences in x-ray scatter distributions were observed between samples from normal and tumour tissue samples using the laboratory based 'SAXSess' system. Albeit from a small number of samples, a sensitivity of 100% was obtained. This result encourages us to pursue the implementation of SAXS as a laboratory based diagnosis technique

  1. Polychromatic X-ray Micro- and Nano-Beam Science and Instrumentation

    Science.gov (United States)

    Ice, G. E.; Larson, B. C.; Liu, W.; Barabash, R. I.; Specht, E. D.; Pang, J. W. L.; Budai, J. D.; Tischler, J. Z.; Khounsary, A.; Liu, C.; Macrander, A. T.; Assoufid, L.

    2007-01-01

    Polychromatic x-ray micro- and nano-beam diffraction is an emerging nondestructive tool for the study of local crystalline structure and defect distributions. Both long-standing fundamental materials science issues, and technologically important questions about specific materials systems can be uniquely addressed. Spatial resolution is determined by the beam size at the sample and by a knife-edge technique called differential aperture microscopy that decodes the origin of scattering from along the penetrating x-ray beam. First-generation instrumentation on station 34-ID-E at the Advanced Photon Source (APS) allows for nondestructive automated recovery of the three-dimensional (3D) local crystal phase and orientation. Also recovered are the local elastic-strain and the dislocation tensor distributions. New instrumentation now under development will further extend the applications of polychromatic microdiffraction and will revolutionize materials characterization.

  2. Polychromatic X-ray Micro- and Nano-Beam Science and Instrumentation

    International Nuclear Information System (INIS)

    Ice, G.E.; Larson, Ben C.; Liu, Wenjun; Barabash, Rozaliya; Specht, Eliot D; Pang, Judy; Budai, John D.; Tischler, Jonathan Zachary; Khounsary, Ali; Liu, Chian; Macrander, Albert T.; Assoufid, Lahsen

    2007-01-01

    Polychromatic x-ray micro- and nano-beam diffraction is an emerging nondestructive tool for the study of local crystalline structure and defect distributions. Both long-standing fundamental materials science issues, and technologically important questions about specific materials systems can be uniquely addressed. Spatial resolution is determined by the beam size at the sample and by a knife-edge technique called differential aperture microscopy that decodes the origin of scattering from along the penetrating x-ray beam. First-generation instrumentation on station 34-ID-E at the Advanced Photon Source (APS) allows for nondestructive automated recovery of the three-dimensional (3D) local crystal phase and orientation. Also recovered are the local elastic-strain and the dislocation tensor distributions. New instrumentation now under development will further extend the applications of polychromatic microdiffraction and will revolutionize materials characterization

  3. Comparative analysis among X-ray mammographic findings, nuclear and histologic grading, and TNM staging of breast carcinoma

    International Nuclear Information System (INIS)

    Park, Jin Sook; Sung, Ki Joon; Cho, Mee Yon; Hong, In Soo; Kim, Myung Soon; Oh, Ki Keun

    1996-01-01

    The purpose of this study was to evaluate the prognosis of breast carcinoma by comparison with X-ray mammographic findings, nuclear and histologic grade, and TNM staging. We retrospectively reviewed 114 cases (113 patients) of breast carcinoma, analysing X-ray mammographic findings of all cases with regard to mass, calcification, and spiculation. In 80 cases of scirrhous invasive ductal breast carcinoma. Black's nuclear and Bloom-Richardson's histologic grade were also evaluated. Mammographic findings and nuclear and histologic grade were compared with TNM staging which might suggest the prognosis of breast carcinoma. X-ray mammographic findings (mass, calcification and spiculation) did not significantly correlate with T staging, but the clinical staging of the spiculation was advanced. These X-ray findings did not significantly correlate with the nuclear grading and the histologic grading. Nuclear grade did not correlate with T and M staging, but correlated significantly with N staging and clinical stage(p < 0.05). Histologic grade did not significantly correlate with TNM staging. The clinical staging of spiculation was advanced and nuclear grade correlated significantly with N stage and clinical staging. X-ray mammographic findings did not directly correlate with nuclear and histologic grading, but combined studies of the evaluation of mammographic findings and nuclear and histologic grade were useful for prognosing breast carcinoma

  4. Impact of large x-ray beam collimation on image quality

    Science.gov (United States)

    Racine, Damien; Ba, Alexandre; Ott, Julien G.; Bochud, François O.; Verdun, Francis R.

    2016-03-01

    Large X-ray beam collimation in computed tomography (CT) opens the way to new image acquisition techniques and improves patient management for several clinical indications. The systems that offer large X-ray beam collimation enable, in particular, a whole region of interest to be investigated with an excellent temporal resolution. However, one of the potential drawbacks of this option might be a noticeable difference in image quality along the z-axis when compared with the standard helical acquisition mode using more restricted X-ray beam collimations. The aim of this project is to investigate the impact of the use of large X-ray beam collimation and new iterative reconstruction on noise properties, spatial resolution and low contrast detectability (LCD). An anthropomorphic phantom and a custom made phantom were scanned on a GE Revolution CT. The images were reconstructed respectively with ASIR-V at 0% and 50%. Noise power spectra, to evaluate the noise properties, and Target Transfer Functions, to evaluate the spatial resolution, were computed. Then, a Channelized Hotelling Observer with Gabor and Dense Difference of Gaussian channels was used to evaluate the LCD using the Percentage correct as a figure of merit. Noticeable differences of 3D noise power spectra and MTF have been recorded; however no significant difference appeared when dealing with the LCD criteria. As expected the use of iterative reconstruction, for a given CTDIvol level, allowed a significant gain in LCD in comparison to ASIR-V 0%. In addition, the outcomes of the NPS and TTF metrics led to results that would contradict the outcomes of CHO model observers if used for a NPWE model observer (Non- Prewhitening With Eye filter). The unit investigated provides major advantages for cardiac diagnosis without impairing the image quality level of standard chest or abdominal acquisitions.

  5. PBFA II lithium beam characterization from inner-shell x-ray images

    International Nuclear Information System (INIS)

    Moats, A.R.; Derzon, M.S.; Chandler, G.A.; Dukart, R.J.; Haill, T.A.

    1994-01-01

    The Particle Beam Fusion Accelerator (PBFA II) is not driving targets with ICF-relevant lithium ion beams. During the most recent lithium beam target series, time-integrated x-ray pinhole cameras viewed the ion-induced inner-shell x-ray fluorescence from the central gold cone target and a titanium-coated strip. Ion beam profiles at a nominal 10 mm radius and fixed azimuthal direction were obtained from images of the Ti K α , fluorescence of a Ti-coated Al diagnostic wire. The gold cone gave us beam profiles at a nominal 3 mm radius and at all azimuthal angles from the Au L α fluorescence. From these profiles, we obtained the ion beam vertical focus position, full-width-at-half-maximum, and the degree of azimuthal uniformity for the lithium target shots. For these initial results, beam steering problems were evident. Azimuthal uniformity was measured from the ion beam footprint on the outer Au case (predominantly Au L α ) of the hohlraum target and were found to be in the same range (up to 30%) as for previous proton beam target series. We then present plans for Li beam diagnostics for an upcoming target experimental series

  6. X-ray body scanner for computerised tomography

    International Nuclear Information System (INIS)

    1977-01-01

    An X-ray source is described whose source is collimated into a thin fan-shaped beam. The detector means is spaced from the sources and both are mounted for scanning and orbiting jointly about a body in a partial or complete resolution. The X-ray intensities thus obtained provide data for reconstructing an image. The detector and source combination and the body are moved relative to one another in an axial direction to enable scanning of the body layers in sequence. In one embodiment the X-ray source is pulsed as it scans, and in another the fan-shaped beam is on continuously and readout is done sequentially. Thus in either case a large number of intensities for each layer are obtained. A high precision encoder system is used to synchronize X-ray pulses and readouts spatially and with line frequency. Means are provided for storing the cables leading to the rotatable source, the detectors and other moveable components. An embodiment for scanning a body part such as a breast has means for conditioning and controlling the water in which the part is immersed. (C.F.)

  7. X-ray beam monitor made by thin-film CVD single-crystal diamond.

    Science.gov (United States)

    Marinelli, Marco; Milani, E; Prestopino, G; Verona, C; Verona-Rinati, G; Angelone, M; Pillon, M; Kachkanov, V; Tartoni, N; Benetti, M; Cannatà, D; Di Pietrantonio, F

    2012-11-01

    A novel beam position monitor, operated at zero bias voltage, based on high-quality chemical-vapor-deposition single-crystal Schottky diamond for use under intense synchrotron X-ray beams was fabricated and tested. The total thickness of the diamond thin-film beam monitor is about 60 µm. The diamond beam monitor was inserted in the B16 beamline of the Diamond Light Source synchrotron in Harwell (UK). The device was characterized under monochromatic high-flux X-ray beams from 6 to 20 keV and a micro-focused 10 keV beam with a spot size of approximately 2 µm × 3 µm square. Time response, linearity and position sensitivity were investigated. Device response uniformity was measured by a raster scan of the diamond surface with the micro-focused beam. Transmissivity and spectral responsivity versus beam energy were also measured, showing excellent performance of the new thin-film single-crystal diamond beam monitor.

  8. Hard X-ray bremsstrahlung production in solar flares by high-energy proton beams

    Science.gov (United States)

    Emslie, A. G.; Brown, J. C.

    1985-01-01

    The possibility that solar hard X-ray bremsstrahlung is produced by acceleration of stationary electrons by fast-moving protons, rather than vice versa, as commonly assumed, was investigated. It was found that a beam of protons which involves 1836 times fewer particles, each having an energy 1836 times greater than that of the electrons in the equivalent electron beam model, has exactly the same bremsstrahlung yield for a given target, i.e., the mechanism has an energetic efficiency equal to that of conventional bremsstrahlung models. Allowance for the different degrees of target ionization appropriate to the two models (for conventional flare geometries) makes the proton beam model more efficient than the electron beam model, by a factor of order three. The model places less stringent constraints than a conventional electron beam model on the flare energy release mechanism. It is also consistent with observed X-ray burst spectra, intensities, and directivities. The altitude distribution of hard X-rays predicted by the model agrees with observations only if nonvertical injection of the protons is assumed. The model is inconsistent with gamma-ray data in terms of conventional modeling.

  9. Optical and x-ray imaging of electron beams using synchrotron emission

    International Nuclear Information System (INIS)

    Wilke, M.

    1995-01-01

    In the case of very low emittance electron and positron storage ring beams, it is impossible to make intrusive measurements of beam properties without increasing the emittance and possibly disrupting the beam. In cases where electron or positron beams have high average power densities (such as free electron laser linacs), intrusive probes such as wires and optical transition radiation screens or Cherenkov emitting screens can be easily damaged or destroyed. The optical and x-ray emissions from the bends in the storage rings and often from linac bending magnets can be used to image the beam profile to obtain emittance information about the beam. The techniques, advantages and limitations of using both optical and x-ray synchrotron emission to measure beam properties are discussed and the possibility of single bunch imaging is considered. The properties of suitable imagers and converters such as phosphors are described. Examples of previous, existing and planned applications are given where available, including a pinhole imaging system currently being designed for the Advanced Photon Source at Argonne National Laboratory

  10. Optical and x-ray imaging of electron beams using synchrotron emission

    International Nuclear Information System (INIS)

    Wilke, M.D.

    1994-01-01

    In the case of very low eniittance electron and positron storage ring beams, it is impossible to make intrusive measurements of beam properties without increasing the emittance and possibly disrupting the beam. In cases where electron or positron beams have high average power densities (such as free electron laser linacs), intrusive probes such as wires and optical transition radiation screens or Cherenkov emitting screens can be easily damaged or destroyed. The optical and x-ray emissions from the bends in the storage rings and often from linac bending magnets can be used to image the beam profile to obtain emittance information about the beam. The techniques, advantages and limitations of using both optical and x-ray synchrotron emission to measure beam properties are discussed and the possibility of single bunch imaging is considered. The properties of suitable imagers and converters such as phosphors are described. Examples of previous, existing and planned applications are given where available, including a pinhole imaging system currently being designed for the Advanced Photon Source at Argonne National Laboratory

  11. Spectral structure of a polycapillary lens shaped X-ray beam

    Science.gov (United States)

    Gogolev, A. S.; Filatov, N. A.; Uglov, S. R.; Hampai, D.; Dabagov, S. B.

    2018-04-01

    Polycapillary X-ray optics is widely used in X-ray analysis techniques to create a small secondary source, for instance, or to deliver X-rays to the point of interest with minimum intensity losses [1]. The main characteristics of the analytical devices on its base are the size and divergence of the focused or translated beam. In this work, we used the photon-counting pixel detector ModuPIX to study the parameters for polycapillary focused X-ray tube radiation as well as the energy and spatial dependences of radiation at the focus. We have characterized the high-speed spectral camera ModuPIX, which is a single Timepix device with a fast parallel readout allowing up to 850 frames per second with 256 × 256 pixels and a 55 μm pitch defined by the frame frequency. By means of the silicon monochromator the energy response function is measured in clustering mode by the energy scan over total X-ray tube spectrum.

  12. Editorial: Focus on X-ray Beams with High Coherence

    Science.gov (United States)

    Robinson, Ian; Gruebel, Gerhard; Mochrie, Simon

    2010-03-01

    This editorial serves as the preface to a special issue of New Journal of Physics, which collects together solicited papers on a common subject, x-ray beams with high coherence. We summarize the issue's content, and explain why there is so much current interest both in the sources themselves and in the applications to the study of the structure of matter and its fluctuations (both spontaneous and driven). As this collection demonstrates, the field brings together accelerator physics in the design of new sources, particle physics in the design of detectors, and chemical and materials scientists who make use of the coherent beams produced. Focus on X-ray Beams with High Coherence Contents Femtosecond pulse x-ray imaging with a large field of view B Pfau, C M Günther, S Schaffert, R Mitzner, B Siemer, S Roling, H Zacharias, O Kutz, I Rudolph, R Treusch and S Eisebitt The FERMI@Elettra free-electron-laser source for coherent x-ray physics: photon properties, beam transport system and applications E Allaria, C Callegari, D Cocco, W M Fawley, M Kiskinova, C Masciovecchio and F Parmigiani Beyond simple exponential correlation functions and equilibrium dynamics in x-ray photon correlation spectroscopy Anders Madsen, Robert L Leheny, Hongyu Guo, Michael Sprung and Orsolya Czakkel The Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS) Sébastien Boutet and Garth J Williams Dynamics and rheology under continuous shear flow studied by x-ray photon correlation spectroscopy Andrei Fluerasu, Pawel Kwasniewski, Chiara Caronna, Fanny Destremaut, Jean-Baptiste Salmon and Anders Madsen Exploration of crystal strains using coherent x-ray diffraction Wonsuk Cha, Sanghoon Song, Nak Cheon Jeong, Ross Harder, Kyung Byung Yoon, Ian K Robinson and Hyunjung Kim Coherence properties of the European XFEL G Geloni, E Saldin, L Samoylova, E Schneidmiller, H Sinn, Th Tschentscher and M Yurkov Fresnel coherent diffractive imaging: treatment and analysis of data G J

  13. Improving x-ray fluorescence signal for benchtop polychromatic cone-beam x-ray fluorescence computed tomography by incident x-ray spectrum optimization: a Monte Carlo study.

    Science.gov (United States)

    Manohar, Nivedh; Jones, Bernard L; Cho, Sang Hyun

    2014-10-01

    To develop an accurate and comprehensive Monte Carlo (MC) model of an experimental benchtop polychromatic cone-beam x-ray fluorescence computed tomography (XFCT) setup and apply this MC model to optimize incident x-ray spectrum for improving production/detection of x-ray fluorescence photons from gold nanoparticles (GNPs). A detailed MC model, based on an experimental XFCT system, was created using the Monte Carlo N-Particle (MCNP) transport code. The model was validated by comparing MC results including x-ray fluorescence (XRF) and scatter photon spectra with measured data obtained under identical conditions using 105 kVp cone-beam x-rays filtered by either 1 mm of lead (Pb) or 0.9 mm of tin (Sn). After validation, the model was used to investigate the effects of additional filtration of the incident beam with Pb and Sn. Supplementary incident x-ray spectra, representing heavier filtration (Pb: 2 and 3 mm; Sn: 1, 2, and 3 mm) were computationally generated and used with the model to obtain XRF/scatter spectra. Quasimonochromatic incident x-ray spectra (81, 85, 90, 95, and 100 keV with 10 keV full width at half maximum) were also investigated to determine the ideal energy for distinguishing gold XRF signal from the scatter background. Fluorescence signal-to-dose ratio (FSDR) and fluorescence-normalized scan time (FNST) were used as metrics to assess results. Calculated XRF/scatter spectra for 1-mm Pb and 0.9-mm Sn filters matched (r ≥ 0.996) experimental measurements. Calculated spectra representing additional filtration for both filter materials showed that the spectral hardening improved the FSDR at the expense of requiring a much longer FNST. In general, using Sn instead of Pb, at a given filter thickness, allowed an increase of up to 20% in FSDR, more prominent gold XRF peaks, and up to an order of magnitude decrease in FNST. Simulations using quasimonochromatic spectra suggested that increasing source x-ray energy, in the investigated range of 81-100 ke

  14. Electron beam produced in a transient hollow cathode discharge: beam electron distribution function, X-ray emission and solid target ablation

    International Nuclear Information System (INIS)

    Nistor, Magdalena

    2000-01-01

    This research thesis aims at a better knowledge of phenomena occurring during transient hollow cathode discharges. The author first recalls the characteristics of such a discharge which make it different from conventional pseudo-spark discharges. The objective is to characterise the electron beam produced within the discharge, and the phenomena associated with its interaction with a solid or gaseous target, leading to the production of an X ray or visible radiation. Thus, the author reports the measurement (by magnetic deflection) of the whole time-averaged electronic distribution function. Such a knowledge is essential for a better use of the electron beam in applications such as X-ray source or material ablation. As high repetition frequency pulse X ray sources are very interesting tools, he reports the development and characterisation of Bremsstrahlung X rays during a beam-target interaction. He finally addresses the implementation of a spectroscopic diagnosis for the filamentary plasma and the ablation of a solid target by the beam [fr

  15. In situ micro-focused X-ray beam characterization with a lensless camera using a hybrid pixel detector

    International Nuclear Information System (INIS)

    Kachatkou, Anton; Marchal, Julien; Silfhout, Roelof van

    2014-01-01

    Position and size measurements of a micro-focused X-ray beam, using an X-ray beam imaging device based on a lensless camera that collects radiation scattered from a thin foil placed in the path of the beam at an oblique angle, are reported. Results of studies on micro-focused X-ray beam diagnostics using an X-ray beam imaging (XBI) instrument based on the idea of recording radiation scattered from a thin foil of a low-Z material with a lensless camera are reported. The XBI instrument captures magnified images of the scattering region within the foil as illuminated by the incident beam. These images contain information about beam size, beam position and beam intensity that is extracted during dedicated signal processing steps. In this work the use of the device with beams for which the beam size is significantly smaller than that of a single detector pixel is explored. The performance of the XBI device equipped with a state-of-the-art hybrid pixel X-ray imaging sensor is analysed. Compared with traditional methods such as slit edge or wire scanners, the XBI micro-focused beam characterization is significantly faster and does not interfere with on-going experiments. The challenges associated with measuring micrometre-sized beams are described and ways of optimizing the resolution of beam position and size measurements of the XBI instrument are discussed

  16. Clinical implementation of a low energy x-ray therapy device in the treatment of breast cancer

    International Nuclear Information System (INIS)

    Haworth, A.; University of Western Australia, WA; Joseph, D.; Lanzon, P.; Caswell, N.; Ebert, M.; University of Western Asutralia, WA

    2001-01-01

    Full text: A low energy device producing x-rays of maximum operating potential of 50kV is used to treat primary breast tumours intraoperatively. In pathologically favourable cases, the treatment replaces conventional external beam irradiation. For patients at greater risk of local recurrence, the treatment replaces conventional 'boost' therapy. The dosimetry of the device will be described in a companion paper. QA tests prior to irradiation include: output calibration/verification; isotropy verification and external radiation monitor (the secondary beam termination device) functionality. The internal radiation monitor count (similar to setting monitor units on a linac) for a prescribed dose is calculated from tables of measured depth dose and applicator factors. The spherical applicator which best suits the size of the excised tumour is lightly sutured into position maintaining as much distance between the skin surface as possible to minimise skin erythema. Radiation protection is achieved with the use of portable lead shields and tungsten impregnated silicon drapes. Patients entered into a TROG randomised clinical trial comparing intraoperative with conventional postoperative radiotherapy after conservative breast surgery for women with early stage breast cancer will be studied in collaboration with the CRC/University College London, Cancer Trials Centre (UK) to record the effects of local tumour control, cosmesis, patient satisfaction and health economics. QA tests take approximately 15 minutes to perform and a treatment prescription of 5Gy at 1cm depth with a 5cm applicator would take approximately 30 minutes. A low energy x-ray device may be used intraoperatively in selected cases to replace conventional radiotherapy minimising the inconvenience for patients and reducing waiting lists on treatment machines. Copyright (2001) Australasian College of Physical Scientists and Engineers in Medicine

  17. An investigation of dose changes for therapeutic kilovoltage x-ray beams with underlying lead shielding

    International Nuclear Information System (INIS)

    Hill, Robin; Healy, Brendan; Holloway, Lois; Baldock, Clive

    2007-01-01

    Kilovoltage x-ray beams are used to treat cancer on or close to the skin surface. Many clinical cases use high atomic number materials as shielding to reduce dose to underlying healthy tissues. In this work, we have investigated the effect on both the surface dose and depth doses in a water phantom with lead shielding at depth in the phantom. The EGSnrc Monte Carlo code was used to simulate the water phantom and to calculate the surface doses and depth doses using primary x-ray beam spectra derived from an analytical model. The x-ray beams were in the energy range of 75-135 kVp with field sizes of 2, 5 and 8 cm diameter. The lead sheet was located beneath the water surface at depths ranging from 0.5-7.5 cm. The surface dose decreased as the lead was positioned closer to the water surface and as the field size was increased. The variation in surface dose as a function of x-ray beam energy was only small but the maximum reduction occurred for the 100 kVp x-ray beam. For the 8 cm diameter field with the lead at 1 cm depth and using the 100 kVp x-ray beam, the surface dose was reduced to 0.898 of the surface dose in the water phantom only. Measured surface dose changes, using a Farmer-type ionization chamber, agreed with the Monte Carlo calculated doses. Calculated depth doses in water with a lead sheet positioned below the surface showed that the dose fall-off increased as the lead was positioned closer to the water surface as compared to the depth dose in the water phantom only. Monte Carlo calculations of the total x-ray beam spectrum at the water surface showed that the total fluence decreased due to a reduction in backscatter from within the water and very little backscatter from the lead. The mean energy of the x-ray spectrum varied less than 1 keV, with the lead at 1 cm beneath the water phantom surface. As the Monte Carlo calculations showed good agreement with the measured results, this method can be used to verify surface dose changes in clinical situations

  18. Beam dynamics simulation in the X-ray Compton source

    International Nuclear Information System (INIS)

    Gladkikh, P.; Karnaukhov, I.; Telegin, Yu.; Shcherbakov, A.; Zelinsky, A.

    2002-01-01

    At the National Science Center 'Kharkov Institute of Physics and Technology' the X-ray source based on Compton scattering has been developed. The computer code for simulation of electron beam dynamics with taking into account the Compton scattering effect based on Monte Carlo method is described in this report. The first results of computer simulation of beam dynamics with electron-photon interaction, parameters of electron and photon beams are presented. Calculations were carried out with the lattice of synchrotron light source SRS-800 Ukrainian Synchrotron Center

  19. Beam dynamics simulation in the X-ray Compton source

    CERN Document Server

    Gladkikh, P; Telegin, Yu P; Shcherbakov, A; Zelinsky, A

    2002-01-01

    At the National Science Center 'Kharkov Institute of Physics and Technology' the X-ray source based on Compton scattering has been developed. The computer code for simulation of electron beam dynamics with taking into account the Compton scattering effect based on Monte Carlo method is described in this report. The first results of computer simulation of beam dynamics with electron-photon interaction, parameters of electron and photon beams are presented. Calculations were carried out with the lattice of synchrotron light source SRS-800 Ukrainian Synchrotron Center.

  20. Multi-mounted X-ray cone-beam computed tomography

    Science.gov (United States)

    Fu, Jian; Wang, Jingzheng; Guo, Wei; Peng, Peng

    2018-04-01

    As a powerful nondestructive inspection technique, X-ray computed tomography (X-CT) has been widely applied to clinical diagnosis, industrial production and cutting-edge research. Imaging efficiency is currently one of the major obstacles for the applications of X-CT. In this paper, a multi-mounted three dimensional cone-beam X-CT (MM-CBCT) method is reported. It consists of a novel multi-mounted cone-beam scanning geometry and the corresponding three dimensional statistical iterative reconstruction algorithm. The scanning geometry is the most iconic design and significantly different from the current CBCT systems. Permitting the cone-beam scanning of multiple objects simultaneously, the proposed approach has the potential to achieve an imaging efficiency orders of magnitude greater than the conventional methods. Although multiple objects can be also bundled together and scanned simultaneously by the conventional CBCT methods, it will lead to the increased penetration thickness and signal crosstalk. In contrast, MM-CBCT avoids substantially these problems. This work comprises a numerical study of the method and its experimental verification using a dataset measured with a developed MM-CBCT prototype system. This technique will provide a possible solution for the CT inspection in a large scale.

  1. TU-F-18C-03: X-Ray Scatter Correction in Breast CT: Advances and Patient Testing

    International Nuclear Information System (INIS)

    Ramamurthy, S; Sechopoulos, I

    2014-01-01

    Purpose: To further develop and perform patient testing of an x-ray scatter correction algorithm for dedicated breast computed tomography (BCT). Methods: A previously proposed algorithm for x-ray scatter signal reduction in BCT imaging was modified and tested with a phantom and on patients. A wireless electronic positioner system was designed and added to the BCT system that positions a tungsten plate in and out of the x-ray beam. The interpolation used by the algorithm was replaced with a radial basis function-based algorithm, with automated exclusion of non-valid sampled points due to patient motion or other factors. A 3D adaptive noise reduction filter was also introduced to reduce the impact of scatter quantum noise post-reconstruction. The impact on image quality of the improved algorithm was evaluated using a breast phantom and seven patient breasts, using quantitative metrics such signal difference (SD) and signal difference-to-noise ratios (SDNR) and qualitatively using image profiles. Results: The improvements in the algorithm resulted in a more robust interpolation step, with no introduction of image artifacts, especially at the imaged object boundaries, which was an issue in the previous implementation. Qualitative evaluation of the reconstructed slices and corresponding profiles show excellent homogeneity of both the background and the higher density features throughout the whole imaged object, as well as increased accuracy in the Hounsfield Units (HU) values of the tissues. Profiles also demonstrate substantial increase in both SD and SDNR between glandular and adipose regions compared to both the uncorrected and system-corrected images. Conclusion: The improved scatter correction algorithm can be reliably used during patient BCT acquisitions with no introduction of artifacts, resulting in substantial improvement in image quality. Its impact on actual clinical performance needs to be evaluated in the future. Research Agreement, Koning Corp., Hologic

  2. Energy dispersive detector for white beam synchrotron x-ray fluorescence imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Matthew D., E-mail: Matt.Wilson@stfc.ac.uk; Seller, Paul; Veale, Matthew C. [Science and Technology Facilities Council, Rutherford Appleton Laboratory, Harwell Campus,UK (United Kingdom); Connolley, Thomas [Diamond Light Source, I12 Beamline, Harwell Campus, Didcot, Oxfordshire (United Kingdom); Dolbnya, Igor P.; Malandain, Andrew; Sawhney, Kawal [Diamond Light Source, B16 Beamline, Harwell Campus, Didcot, Oxfordshire (United Kingdom); Grant, Patrick S.; Liotti, Enzo; Lui, Andrew [Department of Materials, University of Oxford Parks Road, Oxford (United Kingdom)

    2016-07-27

    A novel, “single-shot” fluorescence imaging technique has been demonstrated on the B16 beamline at the Diamond Light Source synchrotron using the HEXITEC energy dispersive imaging detector. A custom made furnace with 200µm thick metal alloy samples was positioned in a white X-ray beam with a hole made in the furnace walls to allow the transmitted beam to be imaged with a conventional X-ray imaging camera consisting of a 500 µm thick single crystal LYSO scintillator, mirror and lens coupled to an AVT Manta G125B CCD sensor. The samples were positioned 45° to the incident beam to enable simultaneous transmission and fluorescence imaging. The HEXITEC detector was positioned at 90° to the sample with a 50 µm pinhole 13 cm from the sample and the detector positioned 2.3m from pinhole. The geometric magnification provided a field of view of 1.1×1.1mm{sup 2} with one of the 80×80 pixels imaging an area equivalent to 13µm{sup 2}. Al-Cu alloys doped with Zr, Ag and Mo were imaged in transmission and fluorescence mode. The fluorescence images showed that the dopant metals could be simultaneously imaged with sufficient counts on all 80x80 pixels within 60 s, with the X-ray flux limiting the fluorescence imaging rate. This technique demonstrated that it is possible to simultaneously image and identify multiple elements on a spatial resolution scale ~10µm or higher without the time consuming need to scan monochromatic energies or raster scan a focused beam of X-rays. Moving to high flux beamlines and using an array of detectors could improve the imaging speed of the technique with element specific imaging estimated to be on a 1 s timescale.

  3. Energy dispersive detector for white beam synchrotron x-ray fluorescence imaging

    International Nuclear Information System (INIS)

    Wilson, Matthew D.; Seller, Paul; Veale, Matthew C.; Connolley, Thomas; Dolbnya, Igor P.; Malandain, Andrew; Sawhney, Kawal; Grant, Patrick S.; Liotti, Enzo; Lui, Andrew

    2016-01-01

    A novel, “single-shot” fluorescence imaging technique has been demonstrated on the B16 beamline at the Diamond Light Source synchrotron using the HEXITEC energy dispersive imaging detector. A custom made furnace with 200µm thick metal alloy samples was positioned in a white X-ray beam with a hole made in the furnace walls to allow the transmitted beam to be imaged with a conventional X-ray imaging camera consisting of a 500 µm thick single crystal LYSO scintillator, mirror and lens coupled to an AVT Manta G125B CCD sensor. The samples were positioned 45° to the incident beam to enable simultaneous transmission and fluorescence imaging. The HEXITEC detector was positioned at 90° to the sample with a 50 µm pinhole 13 cm from the sample and the detector positioned 2.3m from pinhole. The geometric magnification provided a field of view of 1.1×1.1mm"2 with one of the 80×80 pixels imaging an area equivalent to 13µm"2. Al-Cu alloys doped with Zr, Ag and Mo were imaged in transmission and fluorescence mode. The fluorescence images showed that the dopant metals could be simultaneously imaged with sufficient counts on all 80x80 pixels within 60 s, with the X-ray flux limiting the fluorescence imaging rate. This technique demonstrated that it is possible to simultaneously image and identify multiple elements on a spatial resolution scale ~10µm or higher without the time consuming need to scan monochromatic energies or raster scan a focused beam of X-rays. Moving to high flux beamlines and using an array of detectors could improve the imaging speed of the technique with element specific imaging estimated to be on a 1 s timescale.

  4. Structure in defocused beams of x-ray mirrors: causes and possible solutions

    Science.gov (United States)

    Sutter, John P.; Alcock, Simon G.; Rust, Fiona; Wang, Hongchang; Sawhney, Kawal

    2014-09-01

    Grazing incidence mirrors are now a standard optic for focusing X-ray beams. Both bimorph and mechanically bendable mirrors are widely used at Diamond Light Source because they permit a wide choice of focal lengths. They can also be deliberately set out of focus to enlarge the X-ray beam, and indeed many beamline teams now wish to generate uniform beam spots of variable size. However, progress has been slowed by the appearance of fine structure in these defocused beams. Measurements showing the relationship between the medium-frequency polishing error and this structure over a variety of beam sizes will be presented. A theoretical model for the simulations of defocused beams from general mirrors will then be developed. Not only the figure error and its first derivative the slope error, but also the second derivative, the curvature error, must be considered. In conclusion, possible ways to reduce the defocused beam structure by varying the actuators' configuration and settings will be discussed.

  5. X-ray trace element analysis with positive ion beams

    International Nuclear Information System (INIS)

    Davis, R.H.

    1973-01-01

    A new trace element analysis having the advantage that many elements may be detected in a single measurement, based on positive charged particle induced X-ray florescence and on the production of X-rays by heavy ions, is described. Because of the large cross-sections for the production of discrete X-ray and the low yield of continuum radiation, positive charged particle X-ray florescence is a competitive, fast, analytic tool. In the experiment a beam of positive charged particles from an accelerator was directed toward a target. X-rays induced by the bombardment were detected by a Si(Li) detector the ouput from which was amplified and sorted in a multichannel analyzer. For rapid data handling and analysis, the multichannel analyzer or ADC unit was connected to an on-line computer. A large variety of targets prepared in collaboration with the oceanographers have been studied and spectra obtained for different particles having the same velocity are presented to show that the yield of discrete X-rays increases at least as rapidly as Z 2 . While protons of several MeV appear to be already competitive further advantage may be gained by heavy ions at lower energies since the continuum is reduced while the peak ''signals'' retain strength due to the Z 2 dependence. (S.B.)

  6. X-ray diagnostic installation for X-ray tomographic images

    International Nuclear Information System (INIS)

    Haendle, J.; Sklebitz, H.

    1984-01-01

    An exemplary embodiment includes at least one x-ray tube for the generation of an x-ray beam, a patient support, an image detector, and a control generator-connected with the x-ray tube and the image detector-for the purpose of moving the x-ray beam, and in opposition thereto, the image field of the image detector. There is connected to the control generator a layer height computer which calculates the enlargement from the geometric data for the tomogram. The image detector has a circuit-connected with the layer height computer-for the purpose of fading-in a marking for the dimensions in the layer plane

  7. Library based x-ray scatter correction for dedicated cone beam breast CT

    International Nuclear Information System (INIS)

    Shi, Linxi; Zhu, Lei; Vedantham, Srinivasan; Karellas, Andrew

    2016-01-01

    Purpose: The image quality of dedicated cone beam breast CT (CBBCT) is limited by substantial scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose a library-based software approach to suppress scatter on CBBCT images with high efficiency, accuracy, and reliability. Methods: The authors precompute a scatter library on simplified breast models with different sizes using the GEANT4-based Monte Carlo (MC) toolkit. The breast is approximated as a semiellipsoid with homogeneous glandular/adipose tissue mixture. For scatter correction on real clinical data, the authors estimate the breast size from a first-pass breast CT reconstruction and then select the corresponding scatter distribution from the library. The selected scatter distribution from simplified breast models is spatially translated to match the projection data from the clinical scan and is subtracted from the measured projection for effective scatter correction. The method performance was evaluated using 15 sets of patient data, with a wide range of breast sizes representing about 95% of general population. Spatial nonuniformity (SNU) and contrast to signal deviation ratio (CDR) were used as metrics for evaluation. Results: Since the time-consuming MC simulation for library generation is precomputed, the authors’ method efficiently corrects for scatter with minimal processing time. Furthermore, the authors find that a scatter library on a simple breast model with only one input parameter, i.e., the breast diameter, sufficiently guarantees improvements in SNU and CDR. For the 15 clinical datasets, the authors’ method reduces the average SNU from 7.14% to 2.47% in coronal views and from 10.14% to 3.02% in sagittal views. On average, the CDR is improved by a factor of 1.49 in coronal views and 2.12 in sagittal

  8. Library based x-ray scatter correction for dedicated cone beam breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Linxi; Zhu, Lei, E-mail: leizhu@gatech.edu [Nuclear and Radiological Engineering and Medical Physics Programs, The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); Vedantham, Srinivasan; Karellas, Andrew [Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655 (United States)

    2016-08-15

    Purpose: The image quality of dedicated cone beam breast CT (CBBCT) is limited by substantial scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose a library-based software approach to suppress scatter on CBBCT images with high efficiency, accuracy, and reliability. Methods: The authors precompute a scatter library on simplified breast models with different sizes using the GEANT4-based Monte Carlo (MC) toolkit. The breast is approximated as a semiellipsoid with homogeneous glandular/adipose tissue mixture. For scatter correction on real clinical data, the authors estimate the breast size from a first-pass breast CT reconstruction and then select the corresponding scatter distribution from the library. The selected scatter distribution from simplified breast models is spatially translated to match the projection data from the clinical scan and is subtracted from the measured projection for effective scatter correction. The method performance was evaluated using 15 sets of patient data, with a wide range of breast sizes representing about 95% of general population. Spatial nonuniformity (SNU) and contrast to signal deviation ratio (CDR) were used as metrics for evaluation. Results: Since the time-consuming MC simulation for library generation is precomputed, the authors’ method efficiently corrects for scatter with minimal processing time. Furthermore, the authors find that a scatter library on a simple breast model with only one input parameter, i.e., the breast diameter, sufficiently guarantees improvements in SNU and CDR. For the 15 clinical datasets, the authors’ method reduces the average SNU from 7.14% to 2.47% in coronal views and from 10.14% to 3.02% in sagittal views. On average, the CDR is improved by a factor of 1.49 in coronal views and 2.12 in sagittal

  9. Characterization of ion-beam mixed multilayers via grazing x-ray reflectometry

    International Nuclear Information System (INIS)

    Le Boite, M.G.; Traverse, A.; Nevot, L.; Pardo, B.; Corno, J.

    1988-01-01

    The grazing x-ray reflectrometry technique was used as a way to study modifications in metallic multilayers induced by ion-beam irradiation. Due to the high sensitivity of the technique, short-range atomic displacements of an atom A in a layer B can be detected so that the first stages of ion-beam mixing can be investigated. The rate of mixing is measured and the compound A/sub 1-//sub x/B/sub x/ formed at the layers' interfaces is characterized

  10. Is low-energy-ion bombardment generated X-ray emission a secondary mutational source to ion-beam-induced genetic mutation?

    Energy Technology Data Exchange (ETDEWEB)

    Thongkumkoon, P. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thailand Center of Excellence in Physics, Commission on Higher Education, 328 Si Ayutthaya Road, Bangkok 10400 (Thailand); Prakrajang, K. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Faculty of Science, Maejo University, Chiang Mai 50290 (Thailand); Thopan, P.; Yaopromsiri, C. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Suwannakachorn, D. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thailand Center of Excellence in Physics, Commission on Higher Education, 328 Si Ayutthaya Road, Bangkok 10400 (Thailand); Yu, L.D., E-mail: yuld@fnrf.science.cmu.ac.th [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thailand Center of Excellence in Physics, Commission on Higher Education, 328 Si Ayutthaya Road, Bangkok 10400 (Thailand)

    2013-07-15

    Highlights: ► Detected X-ray emission from metal, plastic and biological samples. ► Characteristic X-ray emission was detected from metal but not from non-metals. ► Low-energy ion bombarded bacteria held in different sample holders. ► Bacteria held in metal holder had higher mutation rate than in plastic holder. ► Ion-beam-induced X-ray from biological sample is not a basic mutation source. -- Abstract: Low-energy ion beam biotechnology has achieved tremendous successes in inducing crop mutation and gene transfer. However, mechanisms involved in the related processes are not yet well understood. In ion-beam-induced mutation, ion-bombardment-produced X-ray has been proposed to be one of the secondary mutation sources, but the speculation has not yet been experimentally tested. We carried out this investigation to test whether the low-energy ion-beam-produced X-ray was a source of ion-beam-induced mutation. In the investigation, X-ray emission from 29-keV nitrogen- or argon- ion beam bombarded bacterial Escherichia coli (E. coli) cells held in a metal or plastic sample holder was in situ detected using a highly sensitive X-ray detector. The ion beam bombarded bacterial cells held in different material holders were observed for mutation induction. The results led to a conclusion that secondary X-ray emitted from ion-beam-bombarded biological living materials themselves was not a, or at least a negligible, mutational source, but the ion-beam-induced X-ray emission from the metal that made the sample holder could be a source of mutation.

  11. Is low-energy-ion bombardment generated X-ray emission a secondary mutational source to ion-beam-induced genetic mutation?

    International Nuclear Information System (INIS)

    Thongkumkoon, P.; Prakrajang, K.; Thopan, P.; Yaopromsiri, C.; Suwannakachorn, D.; Yu, L.D.

    2013-01-01

    Highlights: ► Detected X-ray emission from metal, plastic and biological samples. ► Characteristic X-ray emission was detected from metal but not from non-metals. ► Low-energy ion bombarded bacteria held in different sample holders. ► Bacteria held in metal holder had higher mutation rate than in plastic holder. ► Ion-beam-induced X-ray from biological sample is not a basic mutation source. -- Abstract: Low-energy ion beam biotechnology has achieved tremendous successes in inducing crop mutation and gene transfer. However, mechanisms involved in the related processes are not yet well understood. In ion-beam-induced mutation, ion-bombardment-produced X-ray has been proposed to be one of the secondary mutation sources, but the speculation has not yet been experimentally tested. We carried out this investigation to test whether the low-energy ion-beam-produced X-ray was a source of ion-beam-induced mutation. In the investigation, X-ray emission from 29-keV nitrogen- or argon- ion beam bombarded bacterial Escherichia coli (E. coli) cells held in a metal or plastic sample holder was in situ detected using a highly sensitive X-ray detector. The ion beam bombarded bacterial cells held in different material holders were observed for mutation induction. The results led to a conclusion that secondary X-ray emitted from ion-beam-bombarded biological living materials themselves was not a, or at least a negligible, mutational source, but the ion-beam-induced X-ray emission from the metal that made the sample holder could be a source of mutation

  12. An X-ray beam position monitor based on the photoluminescence of helium gas

    Science.gov (United States)

    Revesz, Peter; White, Jeffrey A.

    2005-03-01

    A new method for white beam position monitoring for both bend magnet and wiggler synchrotron X-ray radiation has been developed. This method utilizes visible light luminescence generated as a result of ionization by the intense X-ray flux. In video beam position monitors (VBPMs), the luminescence of helium gas at atmospheric pressure is observed through a view port using a CCD camera next to the beam line. The beam position, profile, integrated intensity and FWHM are calculated from the distribution of luminescence intensity in each captured image by custom software. Misalignment of upstream apertures changes the image profile making VBPMs helpful for initial alignment of upstream beam line components. VBPMs can thus provide more information about the X-ray beam than most beam position monitors (BPMs). A beam position calibration procedure, employing a tilted plane-parallel glass plate placed in front of the camera lens, has also been developed. The accuracy of the VBPM system was measured during a bench-top experiment to be better than 1 μm. The He-luminescence-based VBPM system has been operative on three CHESS beam lines (F hard-bend and wiggler, A-line wiggler and G-line wiggler) for about a year. The beam positions are converted to analog voltages and used as feedback signals for beam stabilization. In our paper we discuss details of VBPM construction and describe further results of its performance.

  13. Beam dynamics simulation in the X-ray Compton source

    Energy Technology Data Exchange (ETDEWEB)

    Gladkikh, P.; Karnaukhov, I.; Telegin, Yu.; Shcherbakov, A. E-mail: shcherbakov@kipt.kharkov.ua; Zelinsky, A

    2002-05-01

    At the National Science Center 'Kharkov Institute of Physics and Technology' the X-ray source based on Compton scattering has been developed. The computer code for simulation of electron beam dynamics with taking into account the Compton scattering effect based on Monte Carlo method is described in this report. The first results of computer simulation of beam dynamics with electron-photon interaction, parameters of electron and photon beams are presented. Calculations were carried out with the lattice of synchrotron light source SRS-800 Ukrainian Synchrotron Center.

  14. Perfect-crystal x-ray optics to treat x-ray coherence

    International Nuclear Information System (INIS)

    Yamazaki, Hiroshi; Ishikawa, Tetsuya

    2007-01-01

    X-ray diffraction of perfect crystals, which serve as x-ray monochromator and collimator, modifies coherence properties of x-ray beams. From the time-dependent Takagi-Taupin equations that x-ray wavefields obey in crystals, the reflected wavefield is formulated as an integral transform of a general incident wavefield with temporal and spatial inhomogeneity. A reformulation of rocking-curve profiles from the field solution of the Takagi-Taupin equations allows experimental evaluation of the mutual coherence function of x-ray beam. The rigorous relationship of the coherence functions between before and after reflection clarifies how the coherence is transferred by a crystal. These results will be beneficial to developers of beamline optics for the next generation synchrotron sources. (author)

  15. Device for the collimation of a high-energy beam, in particular a X-ray beam

    International Nuclear Information System (INIS)

    Peyser, L.F.

    1976-01-01

    The design of apertures made of radiation-absorbing material intended for limiting an aperture for a radiation beam of high energy, in particular an X-ray beam is claimed. The apertures are shaped as trapezoids, are held movably, and are adjustable by means of a control device. (UWI) [de

  16. High resolution stationary digital breast tomosynthesis using distributed carbon nanotube x-ray source array.

    Science.gov (United States)

    Qian, Xin; Tucker, Andrew; Gidcumb, Emily; Shan, Jing; Yang, Guang; Calderon-Colon, Xiomara; Sultana, Shabana; Lu, Jianping; Zhou, Otto; Spronk, Derrek; Sprenger, Frank; Zhang, Yiheng; Kennedy, Don; Farbizio, Tom; Jing, Zhenxue

    2012-04-01

    The purpose of this study is to investigate the feasibility of increasing the system spatial resolution and scanning speed of Hologic Selenia Dimensions digital breast tomosynthesis (DBT) scanner by replacing the rotating mammography x-ray tube with a specially designed carbon nanotube (CNT) x-ray source array, which generates all the projection images needed for tomosynthesis reconstruction by electronically activating individual x-ray sources without any mechanical motion. The stationary digital breast tomosynthesis (s-DBT) design aims to (i) increase the system spatial resolution by eliminating image blurring due to x-ray tube motion and (ii) reduce the scanning time. Low spatial resolution and long scanning time are the two main technical limitations of current DBT technology. A CNT x-ray source array was designed and evaluated against a set of targeted system performance parameters. Simulations were performed to determine the maximum anode heat load at the desired focal spot size and to design the electron focusing optics. Field emission current from CNT cathode was measured for an extended period of time to determine the stable life time of CNT cathode for an expected clinical operation scenario. The source array was manufactured, tested, and integrated with a Selenia scanner. An electronic control unit was developed to interface the source array with the detection system and to scan and regulate x-ray beams. The performance of the s-DBT system was evaluated using physical phantoms. The spatially distributed CNT x-ray source array comprised 31 individually addressable x-ray sources covering a 30 angular span with 1 pitch and an isotropic focal spot size of 0.6 mm at full width at half-maximum. Stable operation at 28 kV(peak) anode voltage and 38 mA tube current was demonstrated with extended lifetime and good source-to-source consistency. For the standard imaging protocol of 15 views over 14, 100 mAs dose, and 2 × 2 detector binning, the projection

  17. A new cone-beam X-ray CT system with a reduced size planar detector

    International Nuclear Information System (INIS)

    Li Liang; Chen Zhiqiang; Zhang Li; Xing Yuxiang; Kang Kejun

    2006-01-01

    In a traditional cone-beam CT system, the cost of product and computation is very high. The authors propose a transversely truncated cone-beam X-ray CT system with a reduced size detector positioned off-center, in which X-ray beams only cover half of the object. The reduced detector size cuts the cost and the X-ray dose of the CT system. The existing CT reconstruction algorithms are not directly applicable in this new CT system. Hence, the authors develop a BPF-type direct backprojection algorithm. Different from the traditional rebinding methods, our algorithm directly backprojects the pretreated projection data without rebinding. This makes the algorithm compact and computationally more efficient. Finally, some numerical simulations and practical experiments are done to validate the proposed algorithm. (authors)

  18. Evaluation of the Beam Quality of Intraoral X-ray Equipment using Intraoral Standard Films

    International Nuclear Information System (INIS)

    Lee, Sang Sub; Kwon, Hyok Rak; Sim, Woo Hyoun; Oh, Seung Hyoun; Lee, Ji Youn; Jeon, Kug Jin; Kim, Kee Deog; Park, Chang Seo

    2000-01-01

    This study was to evaluate the beam quality of intraoral X-ray equipment used at Yonsei University Dental Hospital (YUDH) using the half value layer (HVL) and the characteristic curve of intraoral standard X-ray film. The study was done using the intraoral X-ray equipment used at each clinical department at YUDH. Aluminum filter was used to determine the HVL. Intraoral standard film was used to get the characteristic curve of each intraoral X-ray equipment. Most of the HVLs of intraoral X-ray equipment were higher than the least recommended thickness, but the REX 601 model used at the operative dentistry department and the X-707 model used at the pediatric dentistry department had HVLs lower than the recommended thickness. The slopes of the characteristic curves of films taken using the PANPAS 601 model and REX 601 model at operative dentistry department, the X-70S model of prosthodontic dentistry department, and the REX 601 model at the student clinic were relatively low. HVL and the characteristic curve of X-ray film can be used to evaluate the beam quality of intraoral X-ray equipment. In order to get the best X-ray films with the least radiation exposure to patients and best diagnostic information in clinical dentistry, X-ray equipment should be managed in the planned and organized fashion.

  19. Toward optimal X-ray flux utilization in breast CT

    DEFF Research Database (Denmark)

    Jørgensen, Jakob Heide; Hansen, Per Christian; Sidky, Emil Y.

    2011-01-01

    A realistic computer-simulation of a breast computed tomography (CT) system and subject is constructed. The model is used to investigate the optimal number of views for the scan given a fixed total X-ray fluence. The reconstruction algorithm is based on accurate solution to a constrained......, TVminimization problem, which has received much interest recently for sparse-view CT data....

  20. X-ray beam transfer between hollow fibers for long-distance transport

    International Nuclear Information System (INIS)

    Tanaka, Yoshihito; Matsushita, Ryuki; Shiraishi, Ryutaro; Hasegawa, Takayuki; Ishikawa, Kiyoshi; Sawada, Kei; Kohmura, Yoshiki; Takahashi, Isao

    2016-01-01

    Fiber optics for controlling the x-ray beam trajectory has been examined at the synchrotron facility of SPring-8. Up to now, we have achieved beam deflection by several tens of milli-radian and axis shift of around 75 mm with a 1.5 m-long flexible hollow glass capillary. The achievable beam deflecting angle, axis shift, and timing delay are, in principle, proportional to the length, the square of length and the cube of length, respectively. Thus, for further applications, requiring larger beam shift and pulse delay, longer fibers are indispensable. In order to achieve long-distance transport using the fiber, we thus examined the connection transferring x-rays between fibers in an experimental hutch. The acceptance angle at the input end and the throughput efficiency of the second fiber is consistent with the consideration of the output beam divergence of the first fiber. The enhancement of the transfer efficiency is also discussed for the cases of a closer joint and the use of a refractive lens as a coupler.

  1. X-ray beam transfer between hollow fibers for long-distance transport

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Yoshihito, E-mail: tanaka@sci.u-hyogo.ac.jp; Matsushita, Ryuki; Shiraishi, Ryutaro; Hasegawa, Takayuki; Ishikawa, Kiyoshi [Graduate School of Material Science, University of Hyogo, 3-2-1 Kouto, Kamigori-cho, Sayo-gun, Hyogo 678-1297 (Japan); Sawada, Kei; Kohmura, Yoshiki [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); Takahashi, Isao [Department of Physics, School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Hyogo 669-1337 Japan (Japan)

    2016-07-27

    Fiber optics for controlling the x-ray beam trajectory has been examined at the synchrotron facility of SPring-8. Up to now, we have achieved beam deflection by several tens of milli-radian and axis shift of around 75 mm with a 1.5 m-long flexible hollow glass capillary. The achievable beam deflecting angle, axis shift, and timing delay are, in principle, proportional to the length, the square of length and the cube of length, respectively. Thus, for further applications, requiring larger beam shift and pulse delay, longer fibers are indispensable. In order to achieve long-distance transport using the fiber, we thus examined the connection transferring x-rays between fibers in an experimental hutch. The acceptance angle at the input end and the throughput efficiency of the second fiber is consistent with the consideration of the output beam divergence of the first fiber. The enhancement of the transfer efficiency is also discussed for the cases of a closer joint and the use of a refractive lens as a coupler.

  2. Theoretical estimation of proton induced X-ray emission yield of the trace elements present in the lung and breast cancer

    International Nuclear Information System (INIS)

    Manjunatha, H.C.; Sowmya, N.

    2013-01-01

    X-rays may be produced following the excitation of target atoms induced by an energetic incident ion beam of protons. Proton induced X-ray emission (PIXE) analysis has been used for many years for the determination of elemental composition of materials using X-rays. Recent interest in the proton induced X-ray emission cross section has arisen due to their importance in the rapidly expanding field of PIXE analysis. One of the steps in the analysis is to fit the measured X-ray spectrum with theoretical spectrum. The theoretical cross section and yields are essential for the evaluation of spectrum. We have theoretically evaluated the PIXE cross sections for trace elements in the lung and breast cancer tissues such as Cl, K, Ca,Ti, Cr, Mn, Fe, Ni, Cu, Zn, As, Se, Br, Rb, P, S, Sr, Hg and Pb. The estimated cross section is used in the evaluation of Proton induced X-ray emission spectrum for the given trace elements.We have also evaluated the Proton induced X-ray emission yields in the thin and thick target of the given trace elements. The evaluated Proton induced X-ray emission cross-section, spectrum and yields are graphically represented. Some of these values are also tabulated. Proton induced X-ray emission cross sections and a yield for the given trace elements varies with the energy. PIXE yield depends on a real density and does not on thickness of the target. (author)

  3. X-ray diffraction and imaging with a coherent beam: application to X-ray optical elements and to crystals exhibiting phase inhomogeneities

    International Nuclear Information System (INIS)

    Masiello, F.

    2011-05-01

    The exceptional properties of synchrotron light sources have been exploited in very different disciplines, from archaeology to chemistry, from material science to biology, from medicine to physics. Among these properties it is important to mention the high brilliance, continuum spectrum, high degree of polarization, time structure, small source size and divergence of the beam, the last resulting in a high transversal coherence of the produced radiation. This high transversal coherence of the synchrotron sources has permitted the development of new techniques, e.g. phase contrast imaging, X-ray photon correlation spectroscopy and coherent X-ray diffraction imaging (CXDI). This thesis work will consist essentially of three parts. In the first part it will be presented the work done as a member of the X-ray Optics Group of ESRF in the characterization of high quality diamond crystals foreseen as X-ray optical elements. The characterization has been done using different complementary X-ray techniques, such as high resolution diffraction, topography, grazing incidence diffraction, reflectivity and measurements of the coherence preservation using the Talbot effect. In the second part, I will show the result obtained in the study of the temperature behaviours of the domain in periodically poled ferroelectrics crystals. This type of measurements, based on Bragg-Fresnel diffraction, are possible only thanks to the high degree of coherence of the beam. In the third part, I will present the results obtained in the characterization of diamonds foreseen for applications other than X-ray optical elements. (author)

  4. An experimental evaluation of monochromatic x-ray beam position monitors at diamond light source

    Energy Technology Data Exchange (ETDEWEB)

    Bloomer, Chris, E-mail: chris.bloomer@diamond.ac.uk; Rehm, Guenther; Dolbnya, Igor P. [Diamond Light Source Ltd, Oxfordshire (United Kingdom)

    2016-07-27

    Maintaining the stability of the X-ray beam relative to the sample point is of paramount importance for beamlines and users wanting to perform cutting-edge experiments. The ability to detect, and subsequently compensate for, variations in X-ray beam position with effective diagnostics has multiple benefits: a reduction in commissioning and start-up time, less ‘down-time’, and an improvement in the quality of acquired data. At Diamond Light Source a methodical evaluation of a selection of monochromatic X-ray Beam Position Monitors (XBPMs), using a range of position detection techniques, and from a range of suppliers, was carried out. The results of these experiments are presented, showing the measured RMS noise on the position measurement of each device for a given flux, energy, beam size, and bandwidth. A discussion of the benefits and drawbacks of each of the various devices and techniques is also included.

  5. An experimental evaluation of monochromatic x-ray beam position monitors at diamond light source

    International Nuclear Information System (INIS)

    Bloomer, Chris; Rehm, Guenther; Dolbnya, Igor P.

    2016-01-01

    Maintaining the stability of the X-ray beam relative to the sample point is of paramount importance for beamlines and users wanting to perform cutting-edge experiments. The ability to detect, and subsequently compensate for, variations in X-ray beam position with effective diagnostics has multiple benefits: a reduction in commissioning and start-up time, less ‘down-time’, and an improvement in the quality of acquired data. At Diamond Light Source a methodical evaluation of a selection of monochromatic X-ray Beam Position Monitors (XBPMs), using a range of position detection techniques, and from a range of suppliers, was carried out. The results of these experiments are presented, showing the measured RMS noise on the position measurement of each device for a given flux, energy, beam size, and bandwidth. A discussion of the benefits and drawbacks of each of the various devices and techniques is also included.

  6. A framework for breast cancer visualization using augmented reality x-ray vision technique in mobile technology

    Science.gov (United States)

    Rahman, Hameedur; Arshad, Haslina; Mahmud, Rozi; Mahayuddin, Zainal Rasyid

    2017-10-01

    Breast Cancer patients who require breast biopsy has increased over the past years. Augmented Reality guided core biopsy of breast has become the method of choice for researchers. However, this cancer visualization has limitations to the extent of superimposing the 3D imaging data only. In this paper, we are introducing an Augmented Reality visualization framework that enables breast cancer biopsy image guidance by using X-Ray vision technique on a mobile display. This framework consists of 4 phases where it initially acquires the image from CT/MRI and process the medical images into 3D slices, secondly it will purify these 3D grayscale slices into 3D breast tumor model using 3D modeling reconstruction technique. Further, in visualization processing this virtual 3D breast tumor model has been enhanced using X-ray vision technique to see through the skin of the phantom and the final composition of it is displayed on handheld device to optimize the accuracy of the visualization in six degree of freedom. The framework is perceived as an improved visualization experience because the Augmented Reality x-ray vision allowed direct understanding of the breast tumor beyond the visible surface and direct guidance towards accurate biopsy targets.

  7. LabVIEW control software for scanning micro-beam X-ray fluorescence spectrometer.

    Science.gov (United States)

    Wrobel, Pawel; Czyzycki, Mateusz; Furman, Leszek; Kolasinski, Krzysztof; Lankosz, Marek; Mrenca, Alina; Samek, Lucyna; Wegrzynek, Dariusz

    2012-05-15

    Confocal micro-beam X-ray fluorescence microscope was constructed. The system was assembled from commercially available components - a low power X-ray tube source, polycapillary X-ray optics and silicon drift detector - controlled by an in-house developed LabVIEW software. A video camera coupled to optical microscope was utilized to display the area excited by X-ray beam. The camera image calibration and scan area definition software were also based entirely on LabVIEW code. Presently, the main area of application of the newly constructed spectrometer is 2-dimensional mapping of element distribution in environmental, biological and geological samples with micrometer spatial resolution. The hardware and the developed software can already handle volumetric 3-D confocal scans. In this work, a front panel graphical user interface as well as communication protocols between hardware components were described. Two applications of the spectrometer, to homogeneity testing of titanium layers and to imaging of various types of grains in air particulate matter collected on membrane filters, were presented. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. First dedicated in-beam X-ray measurement in heavy-ion fusion reactions

    Energy Technology Data Exchange (ETDEWEB)

    Berner, C. [Technische Universitaet Muenchen, Lehrstuhl E12 (Germany); RIKEN, Research Group for Superheavy Elements (Japan); Henning, W. [Argonne National Laboratory, Physics Division (United States); RIKEN, Research Group for Superheavy Elements (Japan); Muecher, D.; Gernhaeuser, R.; Hellgartner, S.; Maier, L. [Technische Universitaet Muenchen, Lehrstuhl E12 (Germany); Morita, K.; Morimoto, K.; Kaji, D.; Wakabayashi, Y.; Baba, H. [RIKEN, Research Group for Superheavy Elements (Japan); Lutter, R. [Ludwig-Maximilians-Universitaet, Muenchen (Germany)

    2016-07-01

    We report on an experiment aiming at in-beam X-ray spectroscopy of heavy and superheavy elements (SHE). The goal is to establish K-X-ray spectroscopy as a sensitive tool to identify SHE produced in fusion reactions. SHE, formed after cold or hot fusion, are usually identified via the alpha-decay products, which have to be connected to well-known elements. However, various theories predict spontaneous fission as the dominant decay mode for the daughter nuclides. Additionally, half-lives of these elements are expected to increase to values impeding the identification of SHE solely by their decay. The in-beam identification of the characteristic X-rays would precisely allow to identify the charge number of the produced SHE. Experiments were performed at the RIKEN Nishina Centre for Accelerator based Science by using the gas-filled magnet separator GARIS for superheavy element detection. A high-purity, low-energy planar germanium LEGe-detector was adapted to the GARIS system at the target place for the first time in order to measure the element-characteristic, prompt X-ray emission.

  9. A split-beam probe-pump-probe scheme for femtosecond time resolved protein X-ray crystallography

    Directory of Open Access Journals (Sweden)

    Jasper J. van Thor

    2015-01-01

    Full Text Available In order to exploit the femtosecond pulse duration of X-ray Free-Electron Lasers (XFEL operating in the hard X-ray regime for ultrafast time-resolved protein crystallography experiments, critical parameters that determine the crystallographic signal-to-noise (I/σI must be addressed. For single-crystal studies under low absorbed dose conditions, it has been shown that the intrinsic pulse intensity stability as well as mode structure and jitter of this structure, significantly affect the crystallographic signal-to-noise. Here, geometrical parameters are theoretically explored for a three-beam scheme: X-ray probe, optical pump, X-ray probe (or “probe-pump-probe” which will allow experimental determination of the photo-induced structure factor amplitude differences, ΔF, in a ratiometric manner, thereby internally referencing the intensity noise of the XFEL source. In addition to a non-collinear split-beam geometry which separates un-pumped and pumped diffraction patterns on an area detector, applying an additional convergence angle to both beams by focusing leads to integration over mosaic blocks in the case of well-ordered stationary protein crystals. Ray-tracing X-ray diffraction simulations are performed for an example using photoactive yellow protein crystals in order to explore the geometrical design parameters which would be needed. The specifications for an X-ray split and delay instrument that implements both an offset angle and focused beams are discussed, for implementation of a probe-pump-probe scheme at the European XFEL. We discuss possible extension of single crystal studies to serial femtosecond crystallography, particularly in view of the expected X-ray damage and ablation due to the first probe pulse.

  10. X-ray beam splitting design for concurrent imaging at hard X-ray FELs and synchrotron facilities

    Energy Technology Data Exchange (ETDEWEB)

    Oberta, P., E-mail: peter.oberta@rigaku.com [Institute of Physics, Academy of Sciences of the Czech Republic, v.v.i., Na Slovance 2, Praha 8, CZ-18221 (Czech Republic); Rigaku, Novodvorská 994, Praha 4, CZ-14221 (Czech Republic); Mokso, R. [Swiss Light Source, Paul Scherrer Institut, Villigen, CH-5232 Villigen (Switzerland)

    2013-11-21

    A new configuration of diffractive–refractive optics for beam splitting is investigated. The set-up can be applied to perform imaging with two beams simultaneously. It brings advantages toward dynamic studies using image guided diffraction or fluorescence spectroscopy. The optimal energy range of operation for the beam-splitter is between 7 keV and 24 keV, reaching best efficiency at an energy of 10 keV. Due to the long focusing distances (several tens of meters) created by the diffractive–refractive optics and the higher refraction efficiency in the softer energy range, the presented set-ups are ideal for hard X-ray FEL sources.

  11. Geometric calibration of a stationary digital breast tomosynthesis system based on distributed carbon nanotube X-ray source arrays.

    Directory of Open Access Journals (Sweden)

    Changhui Jiang

    Full Text Available Stationary digital breast tomosynthesis (sDBT with distributed X-ray sources based on carbon nanotube (CNT field emission cathodes has been recently proposed as an approach that can prevent motion blur produced by traditional DBT systems. In this paper, we simulate a geometric calibration method based on a proposed multi-source CNT X-ray sDBT system. This method is a projection matrix-based approach with seven geometric parameters, all of which can be obtained from only one projection datum of the phantom. To our knowledge, this study reports the first application of this approach in a CNT-based multi-beam X-ray sDBT system. The simulation results showed that the extracted geometric parameters from the calculated projection matrix are extremely close to the input values and that the proposed method is effective and reliable for a square sDBT system. In addition, a traditional cone-beam computed tomography (CT system was also simulated, and the uncalibrated and calibrated geometric parameters were used in image reconstruction based on the filtered back-projection (FBP method. The results indicated that the images reconstructed with calibrated geometric parameters have fewer artifacts and are closer to the reference image. All the simulation tests showed that this geometric calibration method is optimized for sDBT systems but can also be applied to other application-specific CT imaging systems.

  12. Geometric calibration of a stationary digital breast tomosynthesis system based on distributed carbon nanotube X-ray source arrays.

    Science.gov (United States)

    Jiang, Changhui; Zhang, Na; Gao, Juan; Hu, Zhanli

    2017-01-01

    Stationary digital breast tomosynthesis (sDBT) with distributed X-ray sources based on carbon nanotube (CNT) field emission cathodes has been recently proposed as an approach that can prevent motion blur produced by traditional DBT systems. In this paper, we simulate a geometric calibration method based on a proposed multi-source CNT X-ray sDBT system. This method is a projection matrix-based approach with seven geometric parameters, all of which can be obtained from only one projection datum of the phantom. To our knowledge, this study reports the first application of this approach in a CNT-based multi-beam X-ray sDBT system. The simulation results showed that the extracted geometric parameters from the calculated projection matrix are extremely close to the input values and that the proposed method is effective and reliable for a square sDBT system. In addition, a traditional cone-beam computed tomography (CT) system was also simulated, and the uncalibrated and calibrated geometric parameters were used in image reconstruction based on the filtered back-projection (FBP) method. The results indicated that the images reconstructed with calibrated geometric parameters have fewer artifacts and are closer to the reference image. All the simulation tests showed that this geometric calibration method is optimized for sDBT systems but can also be applied to other application-specific CT imaging systems.

  13. Quantitative breast tissue characterization using grating-based x-ray phase-contrast imaging

    Science.gov (United States)

    Willner, M.; Herzen, J.; Grandl, S.; Auweter, S.; Mayr, D.; Hipp, A.; Chabior, M.; Sarapata, A.; Achterhold, K.; Zanette, I.; Weitkamp, T.; Sztrókay, A.; Hellerhoff, K.; Reiser, M.; Pfeiffer, F.

    2014-04-01

    X-ray phase-contrast imaging has received growing interest in recent years due to its high capability in visualizing soft tissue. Breast imaging became the focus of particular attention as it is considered the most promising candidate for a first clinical application of this contrast modality. In this study, we investigate quantitative breast tissue characterization using grating-based phase-contrast computed tomography (CT) at conventional polychromatic x-ray sources. Different breast specimens have been scanned at a laboratory phase-contrast imaging setup and were correlated to histopathology. Ascertained tumor types include phylloides tumor, fibroadenoma and infiltrating lobular carcinoma. Identified tissue types comprising adipose, fibroglandular and tumor tissue have been analyzed in terms of phase-contrast Hounsfield units and are compared to high-quality, high-resolution data obtained with monochromatic synchrotron radiation, as well as calculated values based on tabulated tissue properties. The results give a good impression of the method’s prospects and limitations for potential tumor detection and the associated demands on such a phase-contrast breast CT system. Furthermore, the evaluated quantitative tissue values serve as a reference for simulations and the design of dedicated phantoms for phase-contrast mammography.

  14. Wavelength dispersive X-ray absorption fine structure imaging by parametric X-ray radiation

    International Nuclear Information System (INIS)

    Inagaki, Manabu; Sakai, Takeshi; Sato, Isamu; Hayakawa, Yasushi; Nogami, Kyoko; Tanaka, Toshinari; Hayakawa, Ken; Nakao, Keisuke

    2008-01-01

    The parametric X-ray radiation (PXR) generator system at Laboratory for Electron Beam Research and Application (LEBRA) in Nihon University is a monochromatic and coherent X-ray source with horizontal wavelength dispersion. The energy definition of the X-rays, which depends on the horizontal size of the incident electron beam on the generator target crystal, has been investigated experimentally by measuring the X-ray absorption near edge structure (XANES) spectra on Cu and CuO associated with conventional X-ray absorption imaging technique. The result demonstrated the controllability of the spectrum resolution of XANES by adjusting of the horizontal electron beam size on the target crystal. The XANES spectra were obtained with energy resolution of several eV at the narrowest case, which is in qualitative agreement with the energy definition of the PXR X-rays evaluated from geometrical consideration. The result also suggested that the wavelength dispersive X-ray absorption fine structure measurement associated with imaging technique is one of the promising applications of PXR. (author)

  15. Short-wavelength soft-x-ray laser pumped in double-pulse single-beam non-normal incidence

    International Nuclear Information System (INIS)

    Zimmer, D.; Ros, D.; Guilbaud, O.; Habib, J.; Kazamias, S.; Zielbauer, B.; Bagnoud, V.; Ecker, B.; Aurand, B.; Kuehl, T.; Hochhaus, D. C.; Neumayer, P.

    2010-01-01

    We demonstrated a 7.36 nm Ni-like samarium soft-x-ray laser, pumped by 36 J of a neodymium:glass chirped-pulse amplification laser. Double-pulse single-beam non-normal-incidence pumping was applied for efficient soft-x-ray laser generation. In this case, the applied technique included a single-optic focusing geometry for large beam diameters, a single-pass grating compressor, traveling-wave tuning capability, and an optimized high-energy laser double pulse. This scheme has the potential for even shorter-wavelength soft-x-ray laser pumping.

  16. X-ray detector array

    International Nuclear Information System (INIS)

    Houston, J.M.

    1980-01-01

    The object of the invention (an ionization chamber X-ray detector array for use with high speed computerised tomographic imaging apparatus) is to reduce the time required to produce a tomographic image. The detector array described determines the distribution of X-ray intensities in one or more flat, coplanar X-ray beams. It comprises three flat anode sheets parallel to the X-ray beam, a plurality of rod-like cathodes between the anodes, a detector gas between the electrodes and a means for applying a potential between the electrodes. Each of the X-ray sources is collimated to give a narrow, planar section of X-ray photons. Sets of X-ray sources in the array are pulsed simultaneously to obtain X-ray transmission data for tomographic image reconstruction. (U.K.)

  17. X- Ray marking of breast cancer in Mongolia

    International Nuclear Information System (INIS)

    Ranish, A.; Tugsjargal, P.; Tuvshinjargal, D.; Nyamdavaa, N.; Gonchigsuren, D.

    2007-01-01

    Full text: Mammography and other breast imaging techniques such as ultrasound are useful in the evaluation of women who have a sign or symptom that may suggest breast cancer. Physical examination evaluates different tissue characteristics than mammography. We have evaluated mammograms of 1286 patients with breast diseases and detected 107 patients with breast cancer. 25 patients underwent surgery and approved all of mammography diagnosis. In all 122 patients with diagnosed breast cancer, the normal breast X-ray markings have been changed; in 107 cases there were single nodular foci, in 15 patients infiltrative cancer was observed. In 9 cases with absence of cancer lesion on mammography, its secondary signs diagnosed the breast cancer. In 50,8% (62) of cases the visible lesion of the breast cancer was star-shaped, 25.4% (31)- lobed, 16,4% (20)- ovoid, 7,4% (9)- round. The lesion contrast varied differently due to its size; in 58,1%- the lesion was intensive, in 11%- poorly intensive, in 4.7% of all cases the cancer lesion was very vague. In mammography, we observed sprinkled-salt like calcification (7,3%), linear calcification (3,2%) and also irregular calcifications (1,6%). Mammography showed its effectiveness in the early diagnosis of breast cancer. In many cases, the radiographic differentiation between benign and malignant circumscribed masses was difficult or sometimes impossible and we have used other diagnostic modalities like mammography guided biopsy. In many cases, the radiographic differentiation between benign and malignant circumscribed masses was difficult or sometimes impossible and we have used other diagnostic modalities like mammography guided biopsy. (author)

  18. X-ray Beam Spectral Reconstruction Using Laplace Transform and Attenuation Curves

    International Nuclear Information System (INIS)

    Maeng, Seongjin; Lee, Sang Hoo; Kwon, Dahye; Seo, Jihye; Seo, Kyung Won

    2015-01-01

    As the use of X-ray tubes is widely spread mainly for medical diagnostic purposes or industrial applications, there is increasing demand for accurate and convenient way getting of X-ray beam spectral information. While measurement methods may provide quite accurate spectral information, these methods still require expensive detectors (example: HPGe, High Purity Germanium detector) and some conversion of measurement information into real spectrum. It is concluded that Laplace transform-based spectral reconstruction technique given in equations (1) and (2) works well for a 50-kV X-ray source. In this paper we obtained the attenuation curve by the use of MCNPX simulations. We were able to rebuild the X-ray spectrum of 50 kV through this research by Monte Carlo simulation (fitting parameters, a: 1.2921, b: 0.2342, ν: 0.6190, R-squared: 0.9930)

  19. In situ surface/interface x-ray diffractometer for oxide molecular beam epitaxy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. H.; Freeland, J. W.; Hong, Hawoong, E-mail: hhong@aps.anl.gov [Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Tung, I. C. [Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208 (United States); Chang, S.-H.; Bhattacharya, A.; Fong, D. D. [Materials Science Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States)

    2016-01-15

    In situ studies of oxide molecular beam epitaxy by synchrotron x-ray scattering has been made possible by upgrading an existing UHV/molecular beam epitaxy (MBE) six-circle diffractometer system. For oxide MBE growth, pure ozone delivery to the chamber has been made available, and several new deposition sources have been made available on a new 12 in. CF (ConFlat, a registered trademark of Varian, Inc.) flange. X-ray diffraction has been used as a major probe for film growth and structures for the system. In the original design, electron diffraction was intended for the secondary diagnostics available without the necessity of the x-ray and located at separate positions. Deposition of films was made possible at the two diagnostic positions. And, the aiming of the evaporation sources is fixed to the point between two locations. Ozone can be supplied through two separate nozzles for each location. Also two separate thickness monitors are installed. Additional features of the equipment are also presented together with the data taken during typical oxide film growth to illustrate the depth of information available via in situ x-ray techniques.

  20. In situ surface/interface x-ray diffractometer for oxide molecular beam epitaxy

    International Nuclear Information System (INIS)

    Lee, J. H.; Freeland, J. W.; Hong, Hawoong; Tung, I. C.; Chang, S.-H.; Bhattacharya, A.; Fong, D. D.

    2016-01-01

    In situ studies of oxide molecular beam epitaxy by synchrotron x-ray scattering has been made possible by upgrading an existing UHV/molecular beam epitaxy (MBE) six-circle diffractometer system. For oxide MBE growth, pure ozone delivery to the chamber has been made available, and several new deposition sources have been made available on a new 12 in. CF (ConFlat, a registered trademark of Varian, Inc.) flange. X-ray diffraction has been used as a major probe for film growth and structures for the system. In the original design, electron diffraction was intended for the secondary diagnostics available without the necessity of the x-ray and located at separate positions. Deposition of films was made possible at the two diagnostic positions. And, the aiming of the evaporation sources is fixed to the point between two locations. Ozone can be supplied through two separate nozzles for each location. Also two separate thickness monitors are installed. Additional features of the equipment are also presented together with the data taken during typical oxide film growth to illustrate the depth of information available via in situ x-ray techniques

  1. Generation of low KV x-ray portal images with mega-voltage electron beams

    International Nuclear Information System (INIS)

    Kenny, J.; Ebert, M.

    2004-01-01

    Full text: The increasing complexity of radiation therapy plans and reduced target margins, have made accurate localization of patients at treatment a crucial quality assurance issue. Mega-voltage portal images, the standard for treatment localization, are inherently low in contrast because x-ray attenuation at these energies is similar for most body tissues. Thus anatomical features are difficult to distinguish and match to features on a reference diagnostic image. This project investigates the possibly of using x-rays created by an external target placed in the path of a clinical mega-voltage electron beam. This target is optimised to produce a higher proportion of useful imaging x-rays in the range of 50-200kV. It is thought that a high efficiency Varian aSi500 amorphous silicon EPID will be sufficient to compensate for the very low efficiency of x-ray production. The project was undertaken with concurrent theoretical and experimental components. The former involved Monte Carlo models of low Z target design while in the later, experimental data was gathered to validate the model and explore the practical issues associated with electron mode image acquisition. A 6 MeV electron beam model for a Varian Clinac 21EX was developed with EGS4/BEAMnrc User Code and compared to measured beam data. Phase space data scored at the secondary collimator then became the input for simulations of a target placed in the accessory tray. Target materials were predominately low atomic number (Z) because a) production of high energy x-rays is minimized and, b) fewer low energy x-rays produced will be absorbed within the target. Photon and electron energy spectrums of the modified beam were evaluated for a range of target geometries. Ultimately, several materials were used in combination to optimise an x-ray yield for energies <200kV while removing electrons and very low energy x-rays, that contribute to patient dose but not to image formation. Low energy images of a PIPs EPID QA

  2. Design and performance of coded aperture optical elements for the CESR-TA x-ray beam size monitor

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, J.P.; Chatterjee, A.; Conolly, C.; Edwards, E.; Ehrlichman, M.P. [Cornell University, Ithaca, NY 14853 (United States); Flanagan, J.W. [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan); Department of Accelerator Science, Graduate University for Advanced Studies (SOKENDAI), Tsukuba (Japan); Fontes, E. [Cornell University, Ithaca, NY 14853 (United States); Heltsley, B.K., E-mail: bkh2@cornell.edu [Cornell University, Ithaca, NY 14853 (United States); Lyndaker, A.; Peterson, D.P.; Rider, N.T.; Rubin, D.L.; Seeley, R.; Shanks, J. [Cornell University, Ithaca, NY 14853 (United States)

    2014-12-11

    We describe the design and performance of optical elements for an x-ray beam size monitor (xBSM), a device measuring e{sup +} and e{sup −} beam sizes in the CESR-TA storage ring. The device can measure vertical beam sizes of 10–100μm on a turn-by-turn, bunch-by-bunch basis at e{sup ±} beam energies of ∼2–5GeV. x-rays produced by a hard-bend magnet pass through a single- or multiple-slit (coded aperture) optical element onto a detector. The coded aperture slit pattern and thickness of masking material forming that pattern can both be tuned for optimal resolving power. We describe several such optical elements and show how well predictions of simple models track measured performances. - Highlights: • We characterize optical element performance of an e{sup ±} x-ray beam size monitor. • We standardize beam size resolving power measurements to reference conditions. • Standardized resolving power measurements compare favorably to model predictions. • Key model features include simulation of photon-counting statistics and image fitting. • Results validate a coded aperture design optimized for the x-ray spectrum encountered.

  3. Design of x-ray diagnostic beam line for a synchrotron radiation source and measurement results

    Energy Technology Data Exchange (ETDEWEB)

    Garg, Akash Deep, E-mail: akash-deep@rrcat.gov.in; Karnewar, A.K.; Ojha, A.; Shrivastava, B.B.; Holikatti, A.C.; Puntambekar, T.A.; Navathe, C.P.

    2014-08-01

    Indus-2 is a 2.5 GeV synchrotron radiation source (SRS) operational at the Raja Ramanna Centre for Advanced Technology (RRCAT) in India. We have designed, developed and commissioned x-ray diagnostic beam line (X-DBL) at the Indus-2. It is based on pinhole array imaging (8–18 keV). We have derived new equations for online measurements of source position and emission angle with pinhole array optics. Measured values are compared with the measurements at an independent x-ray beam position monitor (staggered pair blade monitor) installed in the X-DBL. The measured values are close to the theoretical expected values within ±12 µm (or ±1.5 μrad) for sufficiently wide range of the beam movements. So, beside the beam size and the beam emittance, online information for the vertical position and angle is also used in the orbit steering. In this paper, the various design considerations of the X-DBL and online measurement results are presented.

  4. Cone-beam volume CT mammographic imaging: feasibility study

    Science.gov (United States)

    Chen, Biao; Ning, Ruola

    2001-06-01

    X-ray projection mammography, using a film/screen combination or digital techniques, has proven to be the most effective imaging modality for early detection of breast cancer currently available. However, the inherent superimposition of structures makes small carcinoma (a few millimeters in size) difficult to detect in the occultation case or in dense breasts, resulting in a high false positive biopsy rate. The cone-beam x-ray projection based volume imaging using flat panel detectors (FPDs) makes it possible to obtain three-dimensional breast images. This may benefit diagnosis of the structure and pattern of the lesion while eliminating hard compression of the breast. This paper presents a novel cone-beam volume CT mammographic imaging protocol based on the above techniques. Through computer simulation, the key issues of the system and imaging techniques, including the x-ray imaging geometry and corresponding reconstruction algorithms, x-ray characteristics of breast tissues, x-ray setting techniques, the absorbed dose estimation and the quantitative effect of x-ray scattering on image quality, are addressed. The preliminary simulation results support the proposed cone-beam volume CT mammographic imaging modality in respect to feasibility and practicability for mammography. The absorbed dose level is comparable to that of current two-view mammography and would not be a prominent problem for this imaging protocol. Compared to traditional mammography, the proposed imaging protocol with isotropic spatial resolution will potentially provide significantly better low contrast detectability of breast tumors and more accurate location of breast lesions.

  5. Study of hard braking x-ray radiation on the radiation-beam complex ''TEMP''

    International Nuclear Information System (INIS)

    Batrakov, A.B.; Glushko, E.G.; Egorov, A.M.; Zinchenko, A.A.; Litvinenko, V.V.; Lonin, Yu.F.; Ponomarev, A.G.; Rybka, A.V.; Fedotov, S.I.; Uvarov, V.T.

    2015-01-01

    A calculation over of basic parameters of the hard brake x-rayed radiation for the microsecond accelerating of relativistic electronic beam T EMP . Optimization of converters is conducted for these aims. Maximal doses are experimentally got brake x-rayed radiation on beam-radiation complex T EMP . The diagrams of orientation of the brake x-rayed radiation are taken off depending on energies of bunches and forms of electrodes.

  6. The influence of mammographic X-ray spectra on absorbed energy distribution in breast: Monte Carlo simulation studies

    International Nuclear Information System (INIS)

    Delis, H.; Spyrou, G.; Tzanakos, G.; Panayiotakis, G.

    2005-01-01

    A mathematical model, based on Monte Carlo simulation, is proposed for deriving absorbed energy and dose distribution in mammography utilizing a mathematical water-like phantom. The model was validated for its accuracy against experimental and published data. The main factor discriminating absorbed energy distribution characteristics among different mammographic techniques was considered the X-ray spectrum. The absorbed energy distribution inside the phantom was investigated via percentage depth dose and isodose curves. The influence of the factors affecting X-ray spectrum (tube voltage, anode material, filter material and thickness) on absorbed energy distribution was examined. The hardness of the beam, due to increase of tube voltage or filtration, was found to be the major factor affecting absorbed energy distribution inside the phantom. In general, Mo and W anode systems demonstrated superior dosimetric characteristics against those of W-Mo or Rh. The model presented can be used for estimating absolute and relative breast dose values and their spatial distributions

  7. Optimization of tungsten x-ray spectra for digital mammography: a comparison of model to experiment

    Science.gov (United States)

    Andre, Michael P.; Spivey, Brett A.

    1997-05-01

    Tungsten (W) target x-rays tubes are being studied for use in digital mammography to improve x-ray flux, reduce noise and increase tube heat capacity. A parametric model was developed for digital mammography to evaluate optimization of x-ray spectra for a particular sensor. The model computes spectra and mean glandular doses (MGD) for combinations of W target, beam filters, kVp, breast type and thickness. Two figures of merit were defined: (signal/noise)2/MGD and spectral quantum efficiency; these were computed as a means to approach optimization of object contrast. The model is derived from a combination of classic equations, XCOM from NBS, and published data. X-ray spectra were calculated and measured for filters of Al, Sn, Rh, Mo and Ag on a Eureka tube. (Signal/noise)2/MGD was measured for a filtered W target tube and a digital camera employing CsI scintillator optically coupled to a CCD for which the detective quantum efficiency (DQE) was known. A 3-mm thick acrylic disk was imaged on thickness of 3-8 cm of acrylic and the results were compared to the predictions of the model. The relative error between predicted and measured spectra was +/- 2 percent from 24 to 34 kVp. Calculated MGD as a function of breast thickness, half-value layer and beam filter compares very well to published data. Best performance was found for the following combinations: Mo filter with 30 mm breast, Ag filter with 45 mm, Sn filter for 60 mm, and Al filter for 75 mm thick breast. The parametric model agrees well with measurement and provides a means to explore optimum combinations of kVp and beam filter. For a particular detector, this data may be used with the DQE to estimate total system signal-to-noise ratio for a particular imaging task.

  8. X-ray tube

    International Nuclear Information System (INIS)

    Webley, R.S.

    1975-01-01

    The object of the invention described is to provide an X-ray tube providing a scanned X-ray output which does not require a scanned electron beam. This is obtained by an X-ray tube including an anode which is rotatable about an axis, and a source of a beam of energy, for example an electron beam, arranged to impinge on a surface of the anode to generate X-radiation substantially at the region of incidence on the anode surface. The anode is rotatable about the axis to move the region of incidence over the surface. The anode is so shaped that the rotation causes the region of incidence to move in a predetermined manner relative to fixed parts of the tube so that the generated X-radiation is scanned in a predetermined manner relative to the tube. (UK)

  9. Advanced simulations of x-ray beam propagation through CRL transfocators using ray-tracing and wavefront propagation methods

    DEFF Research Database (Denmark)

    Baltser, Jana; Bergbäck Knudsen, Erik; Vickery, Anette

    2011-01-01

    Compound refractive lenses (CRL) are widely used to manipulate synchrotron radiation beams. Accurate modelling of X-ray beam propagation through individual lenses and through "transfocators" composed of a large number of CRLs is of high importance, since it allows for comprehensive optimization...

  10. X-ray examination apparatus

    NARCIS (Netherlands)

    2000-01-01

    The invention relates to an X-ray apparatus which includes an adjustable X-ray filter. In order to adjust an intensity profile of the X-ray beam, an X-ray absorbing liquid is transported to filter elements of the X-ray filter. Such transport is susceptible to gravitational forces which lead to an

  11. Fabrication of the multilayer beam splitters with large area for soft X-ray laser interferometer

    International Nuclear Information System (INIS)

    Wang Zhanshan; Zhang Zhong; Wang Fengli; Wu Wenjuan; Wang Hongchang; Qin Shuji; Chen Lingyan

    2004-01-01

    The soft X-ray laser Mach-Zehnder interferometer is an important tool to measure the electron densities of a laser-produced plasma near the critical surface. The design of a multilayer beam splitter at 13.9 nm for soft X-ray laser Mach-Zehnder interferometer is completed based on the standard of maximizing product of reflectivity and transmission of the beam splitter. The beam splitters which is Mo/Si multilayers on 10 mm x 10 mm area Si 3 N 4 membrane are fabricated using the magnetron sputtering. The figure error of the beam splitter has reached the deep nanometer magnitude by using optical profiler and the product of reflectivity and transmission measured by synchrotron radiation is up to to 4%. (authors)

  12. Energy dependence evaluation of a ZnO detector for diagnostic X-ray beam

    International Nuclear Information System (INIS)

    Valença, C.P.V.; Silveira, M.A.L.; Macedo, M.A.; Santos, M.A.

    2015-01-01

    In the last decades the international organizations of human health and radiation protection have recommended certain care for using X-ray as a diagnosis tool. The current concern is to avoid any type of radiological accident or overdose to the patient. This can be done assessing the parameters of the X-ray equipment and there are various types of detectors available for that: ionizing chamber, semiconductor devices, etc. These detectors must be calibrated so that they can be used for any energy range and such a procedure is correlated with what is called the energy dependence of the detector. In accordance with the stated requirements of IEC 61267, the standard radiation quality beams and irradiation conditions (RQRs) are the tools and techniques for calibrating diagnostic X-Ray instruments and detectors. The purpose of this work is to evaluate the behavior of the energy dependence of a detector fabricated from a zinc oxide (ZnO) nanofilm. A Pantak industrial X-ray equipment was used to generate the RQR radiation quality beams and test three ZnO detector samples. A 6430 sub-femto-ammeter, Keithley, was used to bias the ZnO detector and simultaneously perform the output readings. The results showed that the ZnO device has some increase in its sensitivity to the ionizing radiation as the X-ray effective energy decreases unlike other types of semiconductor electronic devices typically used as an X-ray detector. We can be concluded that, after calibration, the ZnO device can be used as a diagnostic X-ray detector. (author)

  13. Skin dose from radiotherapy X-ray beams: the influence of energy

    International Nuclear Information System (INIS)

    Butson, M.J.; Metcalfe, P.E.; University of Wollongong, Wollongong, NSW; Mathur, J.N.

    1997-01-01

    Skin-sparing properties of megavoltage photon beams are compromised by electron contamination. Higher energy beams do not necessarily produce lower surface and basal cell layer doses due to this electron contamination. For a 5x5 cm field size the surface doses for 6 MVp and 18 M)p X-ray beams are 10% and 7% of their respective maxima. However, at a field size of 40 x 40cm the percentage surface dose is 42% for both 6 MVp and 18 MVp beams. The introduction of beam modifying devices such as block trays can further reduce the skin-sparing advantages of high energy photon beams. Using a 10 mm perspex block tray, the surface doses for 6 MVp and 18 MVp beams with a 5 x 5 cm field size are 10% and 8%, respectively. At 40 x 40cm, surface doses are 61% and 63% for 6 MVp and 18 MVp beams, respectively. This trend is followed at the basal cell layer depth. At a depth of 1 mm, 18 MVp beam doses are always at least 5% smaller than 6 MVp doses for the same depth at all field sizes when normalized to their respective Dmax values. Results have shown that higher energy photon beams produce a negligible reduction of the delivered dose to the basal cell layer (0.1 mm). Only a small increase in skin sparing is seen at the dermal layer (1 mm), which can be negated by the increased exit dose from an opposing field. (authors)

  14. Nano-fabrication of diffractive optics for soft X-ray and atom beam focusing

    International Nuclear Information System (INIS)

    Rehbein, S.

    2002-01-01

    Nano-structuring processes are described for manufacturing diffractive optics for the condenser-monochromator set-up of the transmission X-ray microscope (TXM) and for the scanning transmission X-ray microscope (STXM) at the BESSY II electron storage ring in Berlin. Furthermore, a process for manufacturing free-standing nickel zone plates for helium atom beam focusing experiments is presented. (author)

  15. High-pressure pair distribution function (PDF) measurement using high-energy focused x-ray beam

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Xinguo, E-mail: xhong@bnl.gov; Weidner, Donald J. [Mineral Physics Institute, Stony Brook University, Stony Brook, NY 11794 (United States); Ehm, Lars [Mineral Physics Institute, Stony Brook University, Stony Brook, NY 11794 (United States); National Synchrotron Light Source II, Brookhaven National Laboratory, Upton, NY 11973 (United States); Zhong, Zhong; Ghose, Sanjit [National Synchrotron Light Source II, Brookhaven National Laboratory, Upton, NY 11973 (United States); Duffy, Thomas S. [Department of Geosciences, Princeton University, Princeton, NJ 08544 (United States)

    2016-07-27

    In this paper, we report recent development of the high-pressure pair distribution function (HP-PDF) measurement technique using a focused high-energy X-ray beam coupled with a diamond anvil cell (DAC). The focusing optics consist of a sagittally bent Laue monochromator and Kirkpatrick-Baez (K–B) mirrors. This combination provides a clean high-energy X-ray beam suitable for HP-PDF research. Demonstration of the HP-PDF technique for nanocrystalline platinum under quasi-hydrostatic condition above 30 GPa is presented.

  16. Power spectrum analysis of the x-ray scatter signal in mammography and breast tomosynthesis projections.

    Science.gov (United States)

    Sechopoulos, Ioannis; Bliznakova, Kristina; Fei, Baowei

    2013-10-01

    To analyze the frequency domain characteristics of the signal in mammography images and breast tomosynthesis projections with patient tissue texture due to detected scattered x-rays. Acquisitions of x-ray projection images of 19 different patient breasts were simulated using previously acquired volumetric patient images. Acquisition of these images was performed with a dedicated breast CT prototype system, and the images were classified into voxels representing skin, adipose, and glandular tissue with a previously validated automated algorithm. The classified three dimensional images then underwent simulated mechanical compression representing that which is performed during acquisition of mammography and breast tomosynthesis images. The acquisition of projection images of each patient breast was simulated using Monte Carlo methods with each simulation resulting in two images: one of the primary (non-scattered) signal and one of the scatter signal. To analyze the scatter signal for both mammography and breast tomosynthesis, two projections images of each patient breast were simulated, one with the x-ray source positioned at 0° (mammography and central tomosynthesis projection) and at 30° (wide tomosynthesis projection). The noise power spectra (NPS) for both the scatter signal alone and the total signal (primary + scatter) for all images were obtained and the combined results of all patients analyzed. The total NPS was fit to the expected power-law relationship NPS(f) = k/f β and the results were compared with those previously published on the power spectrum characteristics of mammographic texture. The scatter signal alone was analyzed qualitatively and a power-law fit was also performed. The mammography and tomosynthesis projections of three patient breasts were too small to analyze, so a total of 16 patient breasts were analyzed. The values of β for the total signal of the 0° projections agreed well with previously published results. As expected, the scatter

  17. Radiation Therapy of Large Intact Breasts Using a Beam Spoiler or Photons with Mixed Energies

    International Nuclear Information System (INIS)

    Lief, Eugene P.; Hunt, Margie A.; Hong, Linda X.; Amols, Howard I.

    2007-01-01

    Radiation treatment of large intact breasts with separations of more than 24 cm is typically performed using x-rays with energies of 10 MV and higher, to eliminate high-dose regions in tissue. The disadvantage of the higher energy beams is the reduced dose to superficial tissue in the buildup region. We evaluated 2 methods of avoiding this underdosage: (1) a beam spoiler: 1.7-cm-thick Lucite plate positioned in the blocking tray 35 cm from the isocenter, with 15-MV x-rays; and (2) combining 6- and 15-MV x-rays through the same portal. For the beam with the spoiler, we measured the dose distribution for normal and oblique incidence using a film and ion chamber in polystyrene, as well as a scanning diode in a water tank. In the mixed-energy approach, we calculated the dose distributions in the buildup region for different proportions of 6- and 15-MV beams. The dose enhancement due to the beam spoiler exhibited significant dependence upon the source-to-skin distance (SSD), field size, and the angle of incidence. In the center of a 20 x 20-cm 2 field at 90-cm SSD, the beam spoiler raises the dose at 5-mm depth from 77% to 87% of the prescription, while maintaining the skin dose below 57%. Comparison of calculated dose with measurements suggested a practical way of treatment planning with the spoiler-usage of 2-mm 'beam' bolus-a special option offered by in-house treatment planning system. A second method of increasing buildup doses is to mix 6- and 15-MV beams. For example, in the case of a parallel-opposed irradiation of a 27-cm-thick phantom, dose to D max for each energy, with respect to midplane, is 114% for pure 6-, 107% for 15-MV beam with the spoiler, and 108% for a 3:1 mixture of 15- and 6-MV beams. Both methods are practical for radiation therapy of large intact breasts

  18. Performance Test of the Next Generation X-Ray Beam Position Monitor System for The APS Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Yang, B.; Lee, S.; Westferro, F.; Jaski, Y.; Lenkszus, F.; Sereno, N.; Ramanathan, M.

    2017-03-25

    The Advanced Photon Source is developing its next major upgrade (APS-U) based on the multi-bend achromat lattice. Improved beam stability is critical for the upgrade and will require keeping short-time beam angle change below 0.25 µrad and long-term angle drift below 0.6 µrad. A reliable white x-ray beam diagnostic system in the front end will be a key part of the planned beam stabilization system. This system includes an x-ray beam position monitor (XBPM) based on x-ray fluorescence (XRF) from two specially designed GlidCop A-15 absorbers, a second XBPM using XRF photons from the Exit Mask, and two white beam intensity monitors using XRF from the photon shutter and Compton-scattered photons from the front end beryllium window or a retractable diamond film in windowless front ends. We present orbit stability data for the first XBPM used in the feedback control during user operations, as well as test data from the second XBPM and the intensity monitors. They demonstrate that the XBPM system meets APS-U beam stability requirements.

  19. A comparison of chemical and ionization dosimetry for high-energy x-ray and electron beams

    International Nuclear Information System (INIS)

    Durocher, J.J.; Boese, H.; Cormack, D.V.; Holloway, A.F.

    1981-01-01

    A comparison was made of ferrous sulfate (Fricke) and ionometric methods for determining the absorbed dose in a phantom irradiated with 4-MV x-rays, 25-MV x-rays, or electron beams having various incident energies between 10 and 32 MeV. Both chemical and ionization instruments were calibrated in a 60 Co beam at a point in water where the absorbed dose had been previously determined. The chemical yield measurements were corrected for spatial variations in dose within the volume of the solution and used to obtain a value of the absorbed dose for each of the x-ray and electron beams. The ratios of G-values required for these determinations were taken from ICRU reports 14 and 21. Ionization instrument readings from three types of commercial ionization chambers were used to obtain alternate values of the absorbed dose for each radiation. C lambda and CE values used in determining these ionization values of dose were also taken from the above ICRU reports. For 4-MV x-rays the values of absorbed dose obtained from chemical measurements agreed to within 0.5% with values obtained from ionization measurements; for 25-MV x-rays the chemical values were about 1% higher than the ionization values; for the electron beams the chemical values were 1%-4% below the ionization values. These discrepancies suggest an inconsistency among the recommended G, C lambda, and CE values similar to that which has been noted by other workers

  20. Heat transfer issues in high-heat-load synchrotron x-ray beams

    International Nuclear Information System (INIS)

    Khounsary, A.M.; Mills, D.M.

    1994-09-01

    In this paper, a short description of the synchrotron radiation x-ray sources and the associated power loads is given, followed by a brief description of typical synchrotron components and their heat load. It is emphasized that the design goals for most of these components is to limit (a) temperature, (b) stresses, or (c) strains in the system. Each design calls for a different geometry, material selection, and cooling scheme. Cooling schemes that have been utilized so far are primarily single phase and include simple macrochannel cooling, microchannel cooling, contact cooling, pin-post cooling, porous-flow cooling, jet cooling, etc. Water, liquid metals, and various cryogenic coolants have been used. Because the trend in x-ray beam development is towards brighter (i.e., more powerful) beams and assuming that no radical changes in the design of x-ray generating machines occurs in the next few years, it is fair to state that the utilization of various effective cooling schemes and, in particular, two-phase flow (e.g., subcooled boiling) warrants further investigation. This, however, requires a thorough examination of stability and reliability of two-phase flows for high-heat-flux components operating in ultrahigh vacuum with stringent reliability requirements

  1. Synchrotron x-ray microbeam characteristics for x-ray fluorescence analysis

    International Nuclear Information System (INIS)

    Iida, Atsuo; Noma, Takashi

    1995-01-01

    X-ray fluorescence analysis using a synchrotron x-ray microprobe has become an indispensable technique for non-destructive micro-analysis. One of the most important parameters that characterize the x-ray microbeam system for x-ray fluorescence analysis is the beam size. For practical analysis, however, the photon flux, the energy resolution and the available energy range are also crucial. Three types of x-ray microbeam systems, including monochromatic and continuum excitation systems, were compared with reference to the sensitivity, the minimum detection limit and the applicability to various types of x-ray spectroscopic analysis. 16 refs., 5 figs

  2. Combined X-ray fluorescence and absorption computed tomography using a synchrotron beam

    International Nuclear Information System (INIS)

    Hall, C

    2013-01-01

    X-ray computed tomography (CT) and fluorescence X-ray computed tomography (FXCT) using synchrotron sources are both useful tools in biomedical imaging research. Synchrotron CT (SRCT) in its various forms is considered an important technique for biomedical imaging since the phase coherence of SR beams can be exploited to obtain images with high contrast resolution. Using a synchrotron as the source for FXCT ensures a fluorescence signal that is optimally detectable by exploiting the beam monochromaticity and polarisation. The ability to combine these techniques so that SRCT and FXCT images are collected simultaneously, would bring distinct benefits to certain biomedical experiments. Simultaneous image acquisition would alleviate some of the registration difficulties which comes from collecting separate data, and it would provide increased information about the sample: functional X-ray images from the FXCT, with the morphological information from the SRCT. A method is presented for generating simultaneous SRCT and FXCT images. Proof of principle modelling has been used to show that it is possible to recover a fluorescence image of a point-like source from an SRCT apparatus by suitably modulating the illuminating planar X-ray beam. The projection image can be successfully used for reconstruction by removing the static modulation from the sinogram in the normal flat and dark field processing. Detection of the modulated fluorescence signal using an energy resolving detector allows the position of a fluorescent marker to be obtained using inverse reconstruction techniques. A discussion is made of particular reconstruction methods which might be applied by utilising both the CT and FXCT data.

  3. Sagittal x-ray beam deviation at asymmetric inclined diffractors

    Czech Academy of Sciences Publication Activity Database

    Korytár, D.; Hrdý, Jaromír; Artemiev, Nikolai; Ferrari, C.; Freund, A.

    2001-01-01

    Roč. 8, - (2001), s. 1136-1139 ISSN 0909-0495 R&D Projects: GA MŠk OK 305; GA MPO PZ-CH/22 Institutional research plan: CEZ:AV0Z1010914 Keywords : x-ray optics * Si(111) W/grooved crystals * inclined diffraction * out-of-diffraction-plane beams * sagittal focusing Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.519, year: 2001

  4. Scintillator materials for x-ray detectors and beam monitors

    Czech Academy of Sciences Publication Activity Database

    Martin, T.; Koch, A.; Nikl, Martin

    2017-01-01

    Roč. 42, č. 6 (2017), s. 451-456 ISSN 0883-7694 R&D Projects: GA ČR GA16-15569S Institutional support: RVO:68378271 Keywords : scintillator * X-ray detector * beam monitor * synchrotron * thin film Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 5.199, year: 2016

  5. Fluctuations on the X-ray intensity beam using a portable X-ray probe based on {sup 6}LiI(Eu) crystal

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Geraldo P.; Oliveira, Arno H. [Universidade Federal de Minas Gerais (PCTN/UFMG), Belo Horizonte, MG (Brazil). Programa de Pos-Graduacao em Ciencias e Tecnicas Nucleares; Carneiro, Andre C.; Carneiro, Clemente J.G.; Milian, Felix M.; Velasco, Fermin G., E-mail: fermin@uesc.b [Universidade Estadual de Santa Cruz (CPqCTR/UESC), Ilheus, BA (Brazil). Centro de Pesquisa em Ciencias e Tecnologias das Radiacoes

    2011-07-01

    X-rays are produced by accelerating electrons with a high voltage and allowing them to collide with a metal target. This high voltage presents fluctuations that define peak, minimum, and average voltages. Different voltages are applied to the X-ray tube depending on the radiographic applications. A rectifier circuit converts the alternating high voltage to unidirectional high voltage to accelerate electrons in this tube. The fluctuations on the energy in the electron beam depend on the mode of rectification. Both energy of the electrons and X rays intensity fluctuates. A portable probe built with a {sup 6}LiI(Eu) detector coupled to a 10 m light guide and a Hamamatsu photon counting head H9319 was used to measuring X ray intensities. This system is designed to collect up to 10000 counts in intervals of 10 ms to 1 s. Counts were accumulated in time intervals of 10 ms during 10 s. The system starts the count before activating the X-ray apparatus, which is on during a time interval of 100ms. During this period, counts may overflow in consequence high voltage was adjusted to be 40kV, in order to avoid such a problem. For each of these points dose was measured using an ionization chamber. The objectives of this work are to study fluctuations on the X-ray beam and to calibrate the portable probe for measuring radiation doses. Counting rates measured for each 10 ms presented strong variations due to high voltages fluctuations. Both dose and counting rate when correlated with distances between source and detector followed the inverse square law and presented values of R2 near of unit. A calibration curve of the portable system for dose measurements showed also R2 value near of unity. (author)

  6. Calibration of screen-type X-ray films for electron beams

    International Nuclear Information System (INIS)

    Kobayashi, T.; Sato, Y.; Yoshida, K.; Tateyama, N.; Komori, Y.; Nakabayashi, T.; Oyamada, M.; Nishimura, J.

    2002-01-01

    In order to extract the maximum performance of the screen-type X-ray film for the detection of cascade showers in emulsion chambers, we examined the effect of the thickness of the phosphor screen by irradiation with 200 MeV electron beams. The observed data is in agreement with our analytical prediction of the radiative transfer of photons in a phosphor screen. If we use a combination of the specially prepared screen, HR16B, with a phosphor layer of 400 μm and a green-sensitive X-ray film, HA30, the detection threshold energy of cascade showers can be considerably lowered down to 140 GeV. (author)

  7. Calibration of screen-type X-ray films for electron beams

    CERN Document Server

    Kobayashi, T; Yoshida, K; Tateyama, N; Komori, Y; Nakabayashi, T; Oyamada, M; Nishimura, J

    2002-01-01

    In order to extract the maximum performance of the screen-type X-ray film for the detection of cascade showers in emulsion chambers, we examined the effect of the thickness of the phosphor screen by irradiation with 200 MeV electron beams. The observed data is in agreement with our analytical prediction of the radiative transfer of photons in a phosphor screen. If we use a combination of the specially prepared screen, HR16B, with a phosphor layer of 400 mu m and a green-sensitive X-ray film, HA30, the detection threshold energy of cascade showers can be considerably lowered down to 140 GeV. (author)

  8. Simulations of x-ray speckle-based dark-field and phase-contrast imaging with a polychromatic beam

    Energy Technology Data Exchange (ETDEWEB)

    Zdora, Marie-Christine, E-mail: marie-christine.zdora@diamond.ac.uk [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, 85748 Garching (Germany); Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE (United Kingdom); Department of Physics & Astronomy, University College London, London WC1E 6BT (United Kingdom); Thibault, Pierre [Department of Physics & Astronomy, University College London, London WC1E 6BT (United Kingdom); Pfeiffer, Franz [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, 85748 Garching (Germany); Zanette, Irene [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, 85748 Garching (Germany); Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE (United Kingdom)

    2015-09-21

    Following the first experimental demonstration of x-ray speckle-based multimodal imaging using a polychromatic beam [I. Zanette et al., Phys. Rev. Lett. 112(25), 253903 (2014)], we present a simulation study on the effects of a polychromatic x-ray spectrum on the performance of this technique. We observe that the contrast of the near-field speckles is only mildly influenced by the bandwidth of the energy spectrum. Moreover, using a homogeneous object with simple geometry, we characterize the beam hardening artifacts in the reconstructed transmission and refraction angle images, and we describe how the beam hardening also affects the dark-field signal provided by speckle tracking. This study is particularly important for further implementations and developments of coherent speckle-based techniques at laboratory x-ray sources.

  9. Carbon-ion beam irradiation kills X-ray-resistant p53-null cancer cells by inducing mitotic catastrophe.

    Directory of Open Access Journals (Sweden)

    Napapat Amornwichet

    Full Text Available BACKGROUND AND PURPOSE: To understand the mechanisms involved in the strong killing effect of carbon-ion beam irradiation on cancer cells with TP53 tumor suppressor gene deficiencies. MATERIALS AND METHODS: DNA damage responses after carbon-ion beam or X-ray irradiation in isogenic HCT116 colorectal cancer cell lines with and without TP53 (p53+/+ and p53-/-, respectively were analyzed as follows: cell survival by clonogenic assay, cell death modes by morphologic observation of DAPI-stained nuclei, DNA double-strand breaks (DSBs by immunostaining of phosphorylated H2AX (γH2AX, and cell cycle by flow cytometry and immunostaining of Ser10-phosphorylated histone H3. RESULTS: The p53-/- cells were more resistant than the p53+/+ cells to X-ray irradiation, while the sensitivities of the p53+/+ and p53-/- cells to carbon-ion beam irradiation were comparable. X-ray and carbon-ion beam irradiations predominantly induced apoptosis of the p53+/+ cells but not the p53-/- cells. In the p53-/- cells, carbon-ion beam irradiation, but not X-ray irradiation, markedly induced mitotic catastrophe that was associated with premature mitotic entry with harboring long-retained DSBs at 24 h post-irradiation. CONCLUSIONS: Efficient induction of mitotic catastrophe in apoptosis-resistant p53-deficient cells implies a strong cancer cell-killing effect of carbon-ion beam irradiation that is independent of the p53 status, suggesting its biological advantage over X-ray treatment.

  10. Estimation of effective dose from limited cone beam X-ray CT examination

    Energy Technology Data Exchange (ETDEWEB)

    Iwai, Kazuo; Arai, Yoshinori; Hashimoto, Koji [Nihon Univ., Tokyo (Japan). School of Dentistry; Nishizawa, Kanae

    2000-12-01

    The limited cone beam X-ray CT (Ortho-CT) was developed on the basis of multi-functional panoramic apparatus, SCANORA (Soredex Co. Helsinki Finland). The imaging intensifier (I.I.) was built in this apparatus as a X-ray detection device instead of X-ray film. The signal provided from I.I. was converted from analog into digital by an analog-digital converter and image reconstitution was done as a three-directional image of the dimensions 3.8 cm of width, 3.0 cm height and 3.8 cm depth with the personal computer. The 3DX Multi image micro CT'' (3DX) was developed along similar lines by MORITA Co., Ltd. (Kyoto, JAPAN). In this study, the stochastic effect on organ and tissue caused by examinations using Ortho-CT and 3DX was measured. The effective dose was estimated according to the recommendation of ICRP60 and was compared with those of panoramic radiography and computed tomography. The irradiation conditions were as follows: 85 kV, 10 mA with the filtration of 3 mmAl and added 1 mmCu for Ortho-CT, and 80 kV, 2 mA and the filtration of 3.1 mmAL for 3DX. The measurement of organ and tissue dose was performed using an anthropomorphic Rando woman phantom (Alderson Research Laboratories Co., Stanfora, CN), as well as by using two different type of thermoluminescent dosimeter (TLD); Panasonic UD-170A (BeO) and UD-110S (CaSO{sub 4}: Tm). The UD-170A was for dose measurement of the inner useful X-ray beams, while the UD-110S was for outer beams. The measured organ and tissue were those recommended with ICRP60 (gonad, breast, bone marrow, lung, thyroid gland, esophagus, stomach, colon, liver, bladder, skin, brain, thymus, adrenal, kidney, spleen, pancrease, upper large intestine, uterus, eyes and major salivary gland). The imaging by Orhto-CT was made in the left maxillary 1st molar, left mandibular 1st molar and temporomandibular joint. 3DX measurement was made in the maxillary incisor region and middle ear regions other than the regions mentioned above. The skin

  11. CRL X-ray tube

    International Nuclear Information System (INIS)

    Kolchevsky, N.N.; Petrov, P.V.

    2015-01-01

    A novel types of X-ray tubes with refractive lenses are proposed. CRL-R X-ray tube consists of Compound Refractive Lens- CRL and Reflection X-ray tube. CRL acts as X-ray window. CRL-T X-ray consists of CRL and Transmission X-ray tube. CRL acts as target for electron beam. CRL refractive lens acts as filter, collimator, waveguide and focusing lens. Properties and construction of the CRL X-ray tube are discussed. (authors)

  12. Dental X-ray apparatus

    International Nuclear Information System (INIS)

    Weiss, M.E.

    1980-01-01

    Intra-oral dental X-ray apparatus for panoramic dental radiography is described in detail. It comprises an electron gun having an elongated tubular target carrier extending into the patient's mouth. The carrier supports an inclined target for direction of an X-ray pattern towards a film positioned externally of the patient's mouth. Image definition is improved by a focusing anode which focuses the electron beam into a sharp spot (0.05 to 0.10 mm diameter) on the target. The potential on the focusing anode is adjustable to vary the size of the spot. An X-ray transmitting ceramic (oxides of Be, Al and Si) window is positioned adjacent to the front face of the target. The electron beam can be magnetically deflected to change the X-ray beam direction. (author)

  13. Application of the entropy concept to describe the quality of a X-ray beam

    International Nuclear Information System (INIS)

    Oliveira, A.D.

    2002-01-01

    In a previous work (Oliveira and Pedroso de Lima, 2000), we introduced the concept of entropy to describe the degradation of the energy of a photon beam incident in a material. We pointed out the relation between both, the entropy of the distribution of the energy deposited in matter and the traditional quality factor of the radiation protection. From the point of view of the entropy, we showed that, in what concerns to the monoenergetic approximation to a polyenergetic beam, we can hardly speak in an approximation (Oliveira 2001). In fact, the behaviour of the entropy is very different for both, an X-ray and a monoenergetic beam. In this work we developed further the study of the degradation of the energy of X-ray photons, from the point of view of the entropy, introducing the concepts of surface entropy, S surf , equilibrium entropy, S eq , and concepts of entropy variation, namely, primary to surface variation, S ps , and total entropy variation, S T . These are characteristic parameters of the X-ray beams describing the degradation of the primary photons while they interact with matter

  14. Electron beam requirements for soft x-ray/XUV free-electron lasers

    International Nuclear Information System (INIS)

    Goldstein, J.C.

    1987-01-01

    A discussion of the electron beam quality (peak current, energy spread, and transverse emittance) required to drive short wavelength free-electron lasers in the XUV (10-100 nm) and soft x-ray (<10 nm) optical wavelength ranges is presented

  15. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... current x-ray images for diagnosis and disease management. top of page How is the procedure performed? ... standards used by radiology professionals. Modern x-ray systems have very controlled x-ray beams and dose ...

  16. Half value layer determination of Al and Cu for different x-ray beams and establishing a relationship between them

    International Nuclear Information System (INIS)

    Kharita, M. H.; Takeyeddin, M.; Wali, K.; Zahili, M.

    2005-03-01

    The Half Value Layer (HVL) of copper and aluminium for special standard x-rays beams (emitted from x-ray machine type Philips MGC30 used in Secondary Standard Dosimetry Laboratory (SSDL) have been determined. The relationship between HVL values of aluminium and copper was established. This relationship can be represented by a non-linear fit. These results are valuable for x-ray workers especially those working in the field of radiation calibration for beam energy determination. Using the results of this study, unavailable thickness of one metal can be replaced by the corresponding thickness of the other metal, for filtration and measurement of x-ray beam. (Authors)

  17. BEAM OPTIMIZATION STUDY FOR AN X-RAY FEL OSCILLATOR AT THE LCLS-II

    Energy Technology Data Exchange (ETDEWEB)

    Qin, Weilun; Huang, S.; Liu, K.X.; Huang, Z; Ding, Y.; Maxwell, T.J.; Kim, K.-J.

    2016-06-01

    The 4 GeV LCLS-II superconducting linac with high repetition beam rate enables the possibility to drive an X-Ray FEL oscillator at harmonic frequencies *. Compared to the regular LCLS-II machine setup, the oscillator mode requires a much longer bunch length with a relatively lower current. Also a flat longitudinal phase space distribution is critical to maintain the FEL gain since the X-ray cavity has extremely narrow bandwidth. In this paper, we study the longitudinal phase space optimization including shaping the initial beam from the injector and optimizing the bunch compressor and dechirper parameters. We obtain a bunch with a flat energy chirp over 400 fs in the core part with current above 100 A. The optimization was based on LiTrack and Elegant simulations using LCLS-II beam parameters.

  18. Glass capillary optics for making x-ray beams of 0.1 to 50 microns diameter

    International Nuclear Information System (INIS)

    Bilderback, Donald H.; Fontes, Ernest

    1997-01-01

    We have fabricated a unique computerized glass puller that can make parabolic or elliptically tapered glass capillaries for microbeam x-ray experiments from hollow glass tubing. We have produced optics that work in a single-bounce imaging mode or in a multi-bounce condensing mode. The imaging-mode capillaries have been used to create 20 to 50 micron diameter x-ray beams at 12 keV that are quite useful for imaging diffraction patterns from tiny bundles of carbon and Kevlar fibers. The condensing-mode capillaries are useful for creating submicron diameter beams and show great promise in x-ray fluorescence applications with femtogram sensitivity for patterned Er and Ti dopants diffused into an optically-active lithium niobate wafer

  19. Photoneutron intensity variation with field size around radiotherapy linear accelerator 18-MeV X-ray beam

    Energy Technology Data Exchange (ETDEWEB)

    Al-Ghamdi, H.; Fazal-ur-Rehman [Physics Department, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia); Al-Jarallah, M.I. [Physics Department, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia)], E-mail: mibrahim@kfupm.edu.sa; Maalej, N. [Physics Department, King Fahd University of Petroleum and Minerals, Dhahran 31261 (Saudi Arabia)

    2008-08-15

    In X-ray radiotherapy accelerators, neutrons are produced mainly by ({gamma},n) reaction when high energy X-rays interact with high Z materials of the linear accelerator head. These materials include the lead (Pb) used as shielding in the collimator, tungsten (W) target used for the production of X-rays and iron (Fe) in the accelerator head. These unwanted neutrons contaminate the therapeutic beam and contribute to the patient dose during the treatment of a cancer patient. Knowing the neutron distribution around the radiotherapy accelerator is therefore desired. CR-39 nuclear track detectors (NTDs) were used to study the variation of fast and thermal neutron relative intensities around an 18 MeV linear accelerator X-ray beam with the field sizes of 0, 10x10, 20x20, 30x30 and 40x40cm{sup 2}. For fast neutron detection, bare NTDs were used. For thermal neutron detection, NTDs were covered with lithium tetra borate (Li{sub 2}B{sub 4}O{sub 7}) converters. The NTDs were placed at different locations in the direction perpendicular to the treatment couch (transversal) and in the direction parallel to the treatment couch (longitudinal) with respect to the isocenter of the accelerator. The fast neutron relative intensity is symmetrical about the beam axis and exhibits an exponential-like drop with distance from the isocenter of the accelerator for all the field sizes. At the primary beam (isocenter), the relative fast neutron intensity is highest for 40x40cm{sup 2} field size and decreases linearly with the decrease in the field size. However, fast neutron intensities do not change significantly with beam size for the measurements outside the primary beam. The fast neutron intensity in the longitudinal direction outside the primary beam decreases linearly with the field size. The thermal neutron intensity, at any location, was found to be almost independent of the field size.

  20. Measurements of fast electron beams and soft X-ray emission from plasma-focus experiments

    Directory of Open Access Journals (Sweden)

    Surała Władysław

    2016-06-01

    Full Text Available The paper reports results of the recent experimental studies of pulsed electron beams and soft X-rays in plasma-focus (PF experiments carried out within a modified PF-360U facility at the NCBJ, Poland. Particular attention was focused on time-resolved measurements of the fast electron beams by means of two different magnetic analyzers, which could record electrons of energy ranging from about 41 keV to about 715 keV in several (6 or 8 measuring channels. For discharges performed with the pure deuterium filling, many strong electron signals were recorded in all the measuring channels. Those signals were well correlated with the first hard X-ray pulse detected by an external scintillation neutron-counter. In some of the analyzer channels, electron spikes (lasting about dozens of nanoseconds and appearing in different instants after the current peculiarity (so-called current dip were also recorded. For several discharges, fast ion beams, which were emitted along the z-axis and recorded with nuclear track detectors, were also investigated. Those measurements confirmed a multibeam character of the ion emission. The time-integrated soft X-ray images, which were taken side-on by means of a pinhole camera and sensitive X-ray films, showed the appearance of some filamentary structures and so-called hot spots. The application of small amounts of admixtures of different heavy noble gases, i.e. of argon (4.8% volumetric, krypton (1.6% volumetric, or xenon (0.8% volumetric, decreased intensity of the recorded electron beams, but increased intensity of the soft X-ray emission and showed more distinct and numerous hot spots. The recorded electron spikes have been explained as signals produced by quasi-mono-energetic microbeams emitted from tiny sources (probably plasma diodes, which can be formed near the observed hot spots.

  1. Compact X-ray sources: X-rays from self-reflection

    Science.gov (United States)

    Mangles, Stuart P. D.

    2012-05-01

    Laser-based particle acceleration offers a way to reduce the size of hard-X-ray sources. Scientists have now developed a simple scheme that produces a bright flash of hard X-rays by using a single laser pulse both to generate and to scatter an electron beam.

  2. Providing Bright-Hard X-ray Beams from a Lower Energy Light Source

    Science.gov (United States)

    Robin, David

    2002-04-01

    At the Advanced Light Source (ALS) there had been an increasing demand for more high brightness harder X-ray sources in the 7 to 40 KeV range. In response to that demand, the ALS storage ring was modified in August 2001. Three 1.3 Tesla normal conducting bending magnets were removed and replaced with three 5 Tesla superconducting magnets (Superbends). The radiation produced by these Superbends is an order of magnitude higher in photon brightness and flux at 12 keV than the 1.3 Tesla bends, making them excellent sources of harder x-rays for protein crystallography and other harder x-ray applications. At the same time the Superbends do not compromise the performance of the facility in the UV and Soft X-ray regions of the spectrum. The Superbends will eventually feed 12 new x-ray beam lines greatly enhancing the facility's capacity in the hard x-ray region. The Superbend project is the biggest upgrade to the ALS storage ring since the ring was commissioned in 1993. In this paper we present, a history of the project, details of the magnet, installation, commissioning, and resulting performance of the ALS with Superbends.

  3. Errors in dual x-ray beam differential absorptiometry

    International Nuclear Information System (INIS)

    Bolin, F.; Preuss, L.; Gilbert, K.; Bugenis, C.

    1977-01-01

    Errors pertinent to the dual beam absorptiometry system have been studied and five areas are given in detail: (1) scattering, in which a computer analysis of multiple scattering shows little error due to this effect; (2) geometrical configuration effects, in which the slope of the sample is shown to influence the accuracy of the measurement; (3) Poisson variations, wherein it is shown that a simultaneous reduction can be obtained in both dosage and statistical error; (4) absorption coefficients, in which the effect of variation in absorption coefficient compilations is shown to have a critical effect on the interpretations of experimental data; and (5) filtering, wherein is shown the need for filters on dual beam systems using a characteristic x-ray output. A zero filter system is outlined

  4. Detection of coherent X-ray transition radiation and its application to beam diagnostics

    International Nuclear Information System (INIS)

    Piestrup, M.A.; Boyers, D.G.; Pincus, C.I.; Li Qiang; Moran, M.J.; Bergstrom, J.C.; Caplan, H.S.; Silzer, R.M.; Skopik, D.M.; Rothbart, G.B.

    1989-01-01

    We investigate the use of coherent X-ray transition radiation to measure the energy of ultra-relativistic charged particles. This can be used for beam diagnostics for both high-repetition-rate and single-pulse, high-current accelerators. The research also has possible applications for the detection and identification of these particles. By selecting foil thickness and spacing, it is possible to design radiators whose angle of emission varies radically over a range of charged particle energies. We have constructed three coherent radiators and tested them at two accelerators using electron beam energies ranging from 50 to 228 MeV. Soft X-ray emission (1-3 keV) was emitted in a circularly symmetrical annulus with half-angle divergence of 2.5-9.0 mrad. The angle of peak emission was found to increase with electron-beam energy, in contrast to the incoherent case for which the angle of emission varies inversely with electron-beam energy. (orig.)

  5. 3D algebraic iterative reconstruction for cone-beam x-ray differential phase-contrast computed tomography.

    Science.gov (United States)

    Fu, Jian; Hu, Xinhua; Velroyen, Astrid; Bech, Martin; Jiang, Ming; Pfeiffer, Franz

    2015-01-01

    Due to the potential of compact imaging systems with magnified spatial resolution and contrast, cone-beam x-ray differential phase-contrast computed tomography (DPC-CT) has attracted significant interest. The current proposed FDK reconstruction algorithm with the Hilbert imaginary filter will induce severe cone-beam artifacts when the cone-beam angle becomes large. In this paper, we propose an algebraic iterative reconstruction (AIR) method for cone-beam DPC-CT and report its experiment results. This approach considers the reconstruction process as the optimization of a discrete representation of the object function to satisfy a system of equations that describes the cone-beam DPC-CT imaging modality. Unlike the conventional iterative algorithms for absorption-based CT, it involves the derivative operation to the forward projections of the reconstructed intermediate image to take into account the differential nature of the DPC projections. This method is based on the algebraic reconstruction technique, reconstructs the image ray by ray, and is expected to provide better derivative estimates in iterations. This work comprises a numerical study of the algorithm and its experimental verification using a dataset measured with a three-grating interferometer and a mini-focus x-ray tube source. It is shown that the proposed method can reduce the cone-beam artifacts and performs better than FDK under large cone-beam angles. This algorithm is of interest for future cone-beam DPC-CT applications.

  6. Detector, collimator and real-time reconstructor for a new scanning-beam digital x-ray (SBDX) prototype.

    Science.gov (United States)

    Speidel, Michael A; Tomkowiak, Michael T; Raval, Amish N; Dunkerley, David A P; Slagowski, Jordan M; Kahn, Paul; Ku, Jamie; Funk, Tobias

    Scanning-beam digital x-ray (SBDX) is an inverse geometry fluoroscopy system for low dose cardiac imaging. The use of a narrow scanned x-ray beam in SBDX reduces detected x-ray scatter and improves dose efficiency, however the tight beam collimation also limits the maximum achievable x-ray fluence. To increase the fluence available for imaging, we have constructed a new SBDX prototype with a wider x-ray beam, larger-area detector, and new real-time image reconstructor. Imaging is performed with a scanning source that generates 40,328 narrow overlapping projections from 71 × 71 focal spot positions for every 1/15 s scan period. A high speed 2-mm thick CdTe photon counting detector was constructed with 320×160 elements and 10.6 cm × 5.3 cm area (full readout every 1.28 μs), providing an 86% increase in area over the previous SBDX prototype. A matching multihole collimator was fabricated from layers of tungsten, brass, and lead, and a multi-GPU reconstructor was assembled to reconstruct the stream of captured detector images into full field-of-view images in real time. Thirty-two tomosynthetic planes spaced by 5 mm plus a multiplane composite image are produced for each scan frame. Noise equivalent quanta on the new SBDX prototype measured 63%-71% higher than the previous prototype. X-ray scatter fraction was 3.9-7.8% when imaging 23.3-32.6 cm acrylic phantoms, versus 2.3-4.2% with the previous prototype. Coronary angiographic imaging at 15 frame/s was successfully performed on the new SBDX prototype, with live display of either a multiplane composite or single plane image.

  7. Development of a Method to Assess the Precision Of the z-axis X-ray Beam Collimation in a CT Scanner

    Science.gov (United States)

    Kim, Yon-Min

    2018-05-01

    Generally X-ray equipment specifies the beam collimator for the accuracy measurement as a quality control item, but the computed tomography (CT) scanner with high dose has no collimator accuracy measurement item. If the radiation dose is to be reduced, an important step is to check if the beam precisely collimates at the body part for CT scan. However, few ways are available to assess how precisely the X-ray beam is collimated. In this regard, this paper provides a way to assess the precision of z-axis X-ray beam collimation in a CT scanner. After the image plate cassette had been exposed to the X-ray beam, the exposed width was automatically detected by using a computer program developed by the research team to calculate the difference between the exposed width and the imaged width (at isocenter). The result for the precision of z-axis X-ray beam collimation showed that the exposed width was 3.8 mm and the overexposure was high at 304% when a narrow beam of a 1.25 mm imaged width was used. In this study, the precision of the beam collimation of the CT scanner, which is frequently used for medical services, was measured in a convenient way by using the image plate (IP) cassette.

  8. Development of isodose curves for A 6 mv x-ray beam

    International Nuclear Information System (INIS)

    Hidaytalla, Lamya Abbas

    1994-08-01

    In this thesis radiation distribution of 6 Mv x-ray beam in a water phantom is developed. The method is based on a simple empirical equation and the assumption that the x-ray source is a point source. This leads to a simple equation for the calculation and plotting of the isodose curves. the charts obtained for two fields, 6*6 and 12*12 cm 2 show good agreement with the previous data used in the isotope and radiation centre, Khartoum hospital. It is suggested that further development should be carried out by writing a computer program for all the fields. (Author)

  9. On beam quality and stopping power ratios for high-energy x-rays

    International Nuclear Information System (INIS)

    Johnsson, S.A.; Ceberg, C.P.; Knoeoes, T.; Nilsson, P.

    2000-01-01

    The aim of this work is to quantitatively compare two commonly used beam quality indices, TPR(20/10) and %dd(10) x , with respect to their ability to predict stopping power ratios (water to air), s w,air , for high-energy x-rays. In particular, effects due to a varied amount of filtration of the photon beam will be studied. A new method for characterizing beam quality is also presented, where the information we strive to obtain is the moments of the spectral distribution. We will show how the moments enter into a general description of the transmission curve and that it is possible to correlate the moments to s w,air with a unique and simple relationship. Comparisons with TPR(20/10) and %dd(10) x show that the moments are well suited for beam quality specification in terms of choosing the correct s w,air . (author)

  10. Simulations of X-ray synchrotron beams using the EGS4 code system in medical applications

    International Nuclear Information System (INIS)

    Orion, I.; Henn, A.; Sagi, I.; Dilmanian, F.A.; Pena, L.; Rosenfeld, A.B.

    2001-01-01

    X-ray synchrotron beams are commonly used in biological and medical research. The availability of intense, polarized low-energy photons from the synchrotron beams provides a high dose transfer to biological materials. The EGS4 code system, which includes the photoelectron angular distribution, electron motion inside a magnetic field, and the LSCAT package, found to be the appropriate Monte Carlo code for synchrotron-produced X-ray simulations. The LSCAT package was developed in 1995 for the EGS4 code to contain the routines to simulate the linear polarization, the bound Compton, and the incoherent scattering functions. Three medical applications were demonstrated using the EGS4 Monte Carlo code as a proficient simulation code system for the synchrotron low-energy X-ray source. (orig.)

  11. Multilayer beam splitter used in a soft X-ray Mach-Zehnder interferometer at working wavelength of 13.9 nm

    International Nuclear Information System (INIS)

    Zhang Zhong; Wang Zhanshan; Wang Hongchang; Wang Fengli; Wu Wenjuan; Zhang Shumin; Qin Shuji; Chen Lingyan

    2006-01-01

    The soft X-ray Mach-Zehnder interferometer is an important tool in measuring the electron densities of laser-produced plasma near the critical surface. The design, fabrication and characterization of multilayer beam splitters at 13.9 nm for soft X-ray Mach-Zehnder interferometer are presented in the paper. The design of beam splitter is completed based on the standard of maximizing product of reflectivity and transmission of the beam splitter at 13.9 nm. The beam splitters, which are Mo/Si multi-layer deposited on 10 mm x 10 mm area, 100 nm thickness Si 3 N 4 membranes, are fabricated using the magnetron sputtering. A method based on extended He-Ne laser beam is developed to analyze the figure error of the beam splitters. The data measured by an optical profiler prove that the method based on visible light is effective to analyze the figure of the beam splitters. The rms figure error of a beam splitter reaches 1.757 nm in the center area 3.82 mm x 3.46 mm and satisfies the need of soft X-ray interference experiment. The product of reflectivity and transmission measured by synchrotron radiation is near to 4%. The Mach-Zehnder interferometer at 13.9 nm based on the multilayer beam splitters is used in 13.9 nm soft X-ray laser interference experiment, in which a clear interferograms of C 8 H 8 laser-produced plasma is got. (authors)

  12. The quality of high-energy X-ray beams

    International Nuclear Information System (INIS)

    LaRiviere, P.D.

    1989-01-01

    Supplement 17 of the British Journal of Radiology is a survey of central-axis depth doses for radiotherapy machines, patterned largely on BJR Supplement 11 (1972). Inspection of high-energy X-ray depth doses for a 10 x 10 cm field at an SSD of 100 cm disclosed large differences between the two sets of data, especially for qualities above 8 MV, e.g. a depth dose of 80% at 10 cm is rated at about 19 MV according to BJR Supplement 11, and 23 MV according to BJR Supplement 17. It was found that Supplement 17 depth-dose data above 8 MV were erratic, but Supplement 11 data could be represented by an analytical expression, providing a unique means of assigning MV quality. It was also found that dose-weighted average energy of the filtered beam plotted smoothly against depth dose. For dosimetric purposes, it is suggested that this parameter be used as a true measure of beam quality, removing discrepancies introduced by the use of nominal MV for this purpose. (author)

  13. DOE/DMS workshop on future synchrotron VUV and x-ray beam Lines

    International Nuclear Information System (INIS)

    Green, P.H.

    1992-03-01

    This document contains an overview of the participating DOE Laboratory beam line interests and the projected science to be addressed on these beam lines, both at new and existing synchrotron facilities. The scientific programs associated with present and planned synchrotron research by DOE Laboratories are discussed in chapters titled ''VUV and Soft X-Ray Research'' and ''Hard X-Ray Research.'' This research encompasses a broad range of the nation's scientific and technical research needs from fundamental to applied, in areas including environmental, biological, and physical sciences; new materials; and energy-related technologies. The projected cost of this proposed construction has been provided in tabular form using a uniform format so that anticipated DOE and outside funding agency contributions for construction and for research and development can be determined. The cost figures are, of course, subject to uncertainties of detailed design requirements and the availability of facility-designed generic components and outside vendors. The report also contains a compendium (as submitted by the beam line proposers) of the design capabilities, the anticipated costs, and the scientific programs of projected beam line construction at the four synchrotron facilities. A summary of the projected cost of these beam lines to be requested of DOE is compiled

  14. Investigation Biological And Medical Specimen Using X-Ray Dark Field Imagine

    International Nuclear Information System (INIS)

    Pattanasiriwisawa, Wanwisa; Sugiyama, Hiroshi; Maksimenko, Anton; Kazuyuki, Hyodo; Ando, Masami

    2005-10-01

    X-ray dark-field imaging (DFI) and bright-field imaging (BFI) in the Laue geometry has been successfully demonstrated. Using a Bragg-case asymmetric monochromator which produces an x-ray beam with a 0.3 μrad divergence incident onto an object and a Laue geometry analyzer that can simultaneously provide DFI and BFI. The imaging technique of DFI is quite novel one that we did not have before in that the central bright line satisfying the Bragg condition is removed by the analyzer crystal and the background radiation obscuring the image of the object does not come to record film. This is not the case in BFI and the strong background radiation obscures the real image of the object. X-ray optics comprising two Laue case diffraction wafers working at 35 keV has been successfully applied to some biological samples such as ivory, tusk, horn, tooth and a phantom of breast cancer. Images of ivory and others have shown very clear and informative inside structure. All pieces of the breast cancer phantom provide us with very fine images to simulate cancer

  15. Long-term stability of beam quality and output of conventional X-ray units.

    Science.gov (United States)

    Fukuda, Atsushi; Matsubara, Kosuke; Miyati, Tosiaki

    2015-01-01

    Conventional diagnostic X-ray units are used for radiographic imaging in many countries. For obtaining entrance surface doses, a numerical dose determination method has been applied in Japan. Although this technique is effective, it has to account for errors, particularly fluctuations, due to the beam quality and output of X-ray tubes. As a part of our quality control procedures, we recorded the entrance surface air kerma, tube voltage, and half-value layer measurements made for four diagnostic X-ray tubes over a 103-week period. The entrance surface air kerma for one of the four X-ray tubes had increased significantly by 11.4 % over 1 year from its initial setting, whereas the tube voltages and half-value layers did not deviate significantly from their initial values. Medical physicists and radiological technologists should be aware of this fluctuation for diagnostic X-ray tubes and take it into consideration when calculating the entrance surface air kerma.

  16. A portable Compton spectrometer for clinical X-ray beams in the energy range 20-150 keV

    International Nuclear Information System (INIS)

    Vieira, A.A.; Linke, A.; Yoshimura, E.M.; Terini, R.A.; Herdade, S.B.

    2011-01-01

    Primary beam spectra were obtained for an X-ray industrial equipment (40-150 kV), and for a clinical mammography apparatus (25-35 kV) from beams scattered at angles close to 90 o , measured with a CdTe Compton spectrometer. Actual scattering angles were determined from the Compton energy shift of characteristic X-rays or spectra end-point energy. Evaluated contribution of coherent scattering amounts to more than 15% of fluence in mammographic beams. This technique can be used in clinical environments.

  17. A beam intensity monitor for the evaluation beamline for soft x-ray optical elements

    International Nuclear Information System (INIS)

    Imazono, Takashi; Moriya, Naoji; Harada, Yoshihisa; Sano, Kazuo; Koike, Masato

    2012-01-01

    Evaluation Beamline for Soft X-Ray Optical Elements (BL-11) at the SR Center of Ritsumeikan University has been operated to measure the wavelength and angular characteristics of soft x-ray optical components in a wavelength range of 0.65-25 nm using a reflecto-diffractometer (RD). The beam intensity monitor that has been equipped in BL-11 has observed the signal of the zero-th order light. For the purpose of more accurate evaluation of the performance of optical components, a new beam intensity monitor to measure the intensity of the first order light from the monochromator in BL-11 has been developed and installed in just front of RD. The strong positive correlation between the signal of the beam monitor and a detector equipped in the RD is shown. It is successful that the beam intensity of the first order light can be monitored in real time.

  18. Matching methods evaluation framework for stereoscopic breast x-ray images.

    Science.gov (United States)

    Rousson, Johanna; Naudin, Mathieu; Marchessoux, Cédric

    2016-01-01

    Three-dimensional (3-D) imaging has been intensively studied in the past few decades. Depth information is an important added value of 3-D systems over two-dimensional systems. Special focuses were devoted to the development of stereo matching methods for the generation of disparity maps (i.e., depth information within a 3-D scene). Dedicated frameworks were designed to evaluate and rank the performance of different stereo matching methods but never considering x-ray medical images. Yet, 3-D x-ray acquisition systems and 3-D medical displays have already been introduced into the diagnostic market. To access the depth information within x-ray stereoscopic images, computing accurate disparity maps is essential. We aimed at developing a framework dedicated to x-ray stereoscopic breast images used to evaluate and rank several stereo matching methods. A multiresolution pyramid optimization approach was integrated to the framework to increase the accuracy and the efficiency of the stereo matching techniques. Finally, a metric was designed to score the results of the stereo matching compared with the ground truth. Eight methods were evaluated and four of them [locally scaled sum of absolute differences (LSAD), zero mean sum of absolute differences, zero mean sum of squared differences, and locally scaled mean sum of squared differences] appeared to perform equally good with an average error score of 0.04 (0 is the perfect matching). LSAD was selected for generating the disparity maps.

  19. Shielding requirements for constant-potential diagnostic x-ray beams determined by a Monte Carlo calculation

    International Nuclear Information System (INIS)

    Simpkin, D.J.

    1989-01-01

    A Monte Carlo calculation has been performed to determine the transmission of broad constant-potential x-ray beams through Pb, concrete, gypsum wallboard, steel and plate glass. The EGS4 code system was used with a simple broad-beam geometric model to generate exposure transmission curves for published 70, 100, 120 and 140-kVcp x-ray spectra. These curves are compared to measured three-phase generated x-ray transmission data in the literature and found to be reasonable. For calculation ease the data are fit to an equation previously shown to describe such curves quite well. These calculated transmission data are then used to create three-phase shielding tables for Pb and concrete, as well as other materials not available in Report No. 49 of the NCRP

  20. Shielding requirements for constant-potential diagnostic x-ray beams determined by a Monte Carlo calculation.

    Science.gov (United States)

    Simpkin, D J

    1989-02-01

    A Monte Carlo calculation has been performed to determine the transmission of broad constant-potential x-ray beams through Pb, concrete, gypsum wallboard, steel and plate glass. The EGS4 code system was used with a simple broad-beam geometric model to generate exposure transmission curves for published 70, 100, 120 and 140-kVcp x-ray spectra. These curves are compared to measured three-phase generated x-ray transmission data in the literature and found to be reasonable. For calculation ease the data are fit to an equation previously shown to describe such curves quite well. These calculated transmission data are then used to create three-phase shielding tables for Pb and concrete, as well as other materials not available in Report No. 49 of the NCRP.

  1. Development of a PIXE (Particle Induced X-ray Emission) analysis device using an extracted proton beam

    International Nuclear Information System (INIS)

    Saidi, A.

    1989-01-01

    The experimental device described allows the extention of the PIXE (Particle Induced X-ray Emission) method to the analysis, by means of proton beams, of solid or liquid samples, which can not be analyzed under vacuum conditions. The homogeneity of the surfaces to be analysed and elements (in the atmosphere) which absorb X-rays must be taken into account. Liquid samples do not need special care. The results show that: at high energies, the extracted beam sensibility is of the same order of magnitude as those obtained under vacuum; at low energies, the performance under vacuum conditions is better. The particles energy losses, at the exit membrane and in the outer atmosphere, decrease the X-rays production efficiency [fr

  2. Soft X-ray radiation damage in EM-CCDs used for Resonant Inelastic X-ray Scattering

    Science.gov (United States)

    Gopinath, D.; Soman, M.; Holland, A.; Keelan, J.; Hall, D.; Holland, K.; Colebrook, D.

    2018-02-01

    Advancement in synchrotron and free electron laser facilities means that X-ray beams with higher intensity than ever before are being created. The high brilliance of the X-ray beam, as well as the ability to use a range of X-ray energies, means that they can be used in a wide range of applications. One such application is Resonant Inelastic X-ray Scattering (RIXS). RIXS uses the intense and tuneable X-ray beams in order to investigate the electronic structure of materials. The photons are focused onto a sample material and the scattered X-ray beam is diffracted off a high resolution grating to disperse the X-ray energies onto a position sensitive detector. Whilst several factors affect the total system energy resolution, the performance of RIXS experiments can be limited by the spatial resolution of the detector used. Electron-Multiplying CCDs (EM-CCDs) at high gain in combination with centroiding of the photon charge cloud across several detector pixels can lead to sub-pixel spatial resolution of 2-3 μm. X-ray radiation can cause damage to CCDs through ionisation damage resulting in increases in dark current and/or a shift in flat band voltage. Understanding the effect of radiation damage on EM-CCDs is important in order to predict lifetime as well as the change in performance over time. Two CCD-97s were taken to PTB at BESSY II and irradiated with large doses of soft X-rays in order to probe the front and back surfaces of the device. The dark current was shown to decay over time with two different exponential components to it. This paper will discuss the use of EM-CCDs for readout of RIXS spectrometers, and limitations on spatial resolution, together with any limitations on instrument use which may arise from X-ray-induced radiation damage.

  3. Reproducibility of temporomandibular joint tomography. Influence of shifted X-ray beam and tomographic focal plane on reproducibility

    International Nuclear Information System (INIS)

    Saito, Masashi

    1999-01-01

    Proper tomographic focal plane and x-ray beam direction are the most important factors to obtain accurate images of the temporomandibular joint (TMJ). In this study, to clarify the magnitude of effect of these two factors on the image quality. We evaluated the reproducibility of tomograms by measuring the distortion when the x-ray beam was shifted from the correct center of the object. The effects of the deviation of the tomographic focal plane on image quality were evaluated by the MTF (Modulation Transfer Function). Two types of tomograms, one the plane type, the other the rotational type were used in this study. A TMJ model was made from Teflon for the purpose of evaluation by shifting the x-ray beam. The x-ray images were obtained by tilting the model from 0 to 10 degrees 2-degree increments. These x-ray images were processed for computer image analysis, and then the distance between condyle and the joint space was measured. To evaluate the influence of the shifted tomographic focal plane on image sharpness, the x-ray images from each setting were analyzed by MTF. To obtain the MTF, ''knife-edge'' made from Pb was used. The images were scanned with a microdensitometer at the central focal plane, and 0, 0.5, 1 mm away respectively. The density curves were analyzed by Fourier analysis and the MTF was calculated. The reproducibility of images became worse by shifting the x-ray beam. This tendency was similar for both tomograms. Object characteristics such as anterior and posterior portion of the joint space affected the deterioration of reproducibility of the tomography. The deviation of the tomographic focal plane also decreased the reproducibility of the x-ray images. The rotational type showed a better MTF, but it became seriously unfavorable with slight changes of the tomographic focal plane. Contrarily, the plane type showed a lower MTF, but the image was stable with shifting of the tomographic focal plane. (author)

  4. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... standards used by radiology professionals. Modern x-ray systems have very controlled x-ray beams and dose control methods to minimize stray (scatter) radiation. This ensures that ...

  5. Stabilized x-ray generator power supply

    International Nuclear Information System (INIS)

    Saha, Subimal; Purushotham, K.V.; Bose, S.K.

    1986-01-01

    X-ray diffraction and X-ray fluorescence analysis are very much adopted in laboratories to determine the type and structure of the constituent compounds in solid materials, chemical composition of materials, stress developed on metals etc. These experiments need X-ray beam of fixed intensity and wave length. This can only be achieved by X-ray generator having highly stabilized tube voltage and tube current. This paper describes how X-ray tube high voltage and electron beam current are stabilized. This paper also highlights generation of X-rays, diffractometry and X-ray fluorescence analysis and their wide applications. Principle of operation for stabilizing the X-ray tube voltage and current, different protection circuits adopted, special features of the mains H.V. transformer and H.T. tank are described in this report. (author)

  6. Acquiring molecular interference functions of X-ray coherent scattering for breast tissues by combination of simulation and experimental methods

    International Nuclear Information System (INIS)

    Chaparian, A.; Oghabian, M. A.; Changizi, V.

    2009-01-01

    Recently, it has been indicated that X-ray coherent scatter from biological tissues can be used to access signature of tissue. Some scientists are interested in studying this effect to get early detection of breast cancer. Since experimental methods for optimization are time consuming and expensive, some scientists suggest using simulation. Monte Carlo codes are the best option for radiation simulation: however, one permanent defect with Monte Carlo codes has been the lack of a sufficient physical model for coherent (Rayleigh) scattering, including molecular interference effects. Materials and Methods: It was decided to obtain molecular interference functions of coherent X-ray scattering for normal breast tissues by combination of modeling and experimental methods. A Monte Carlo simulation program was written to simulate the angular distribution of scattered photons for the normal breast tissue samples. Moreover, experimental diffraction patterns of these tissues were measured by means of energy dispersive X-ray diffraction method. The simulation and experimental data were used to obtain a tabulation of molecular interference functions for breast tissues. Results: With this study a tabulation of molecular interference functions for normal breast tissues Was prepared to facilitate the simulation diffraction patterns of the tissues without any experimental. Conclusion: The method may lead to design new systems for early detection of breast cancer.

  7. Long-term stability of beam quality and output of conventional X-ray units

    OpenAIRE

    Fukuda, Atsushi; Matsubara, Kosuke; Miyati, Toshiaki

    2015-01-01

    Conventional diagnostic X-ray units are used for radiographic imaging in many countries. For obtaining entrance surface doses, a numerical dose determination method has been applied in Japan. Although this technique is effective, it has to account for errors, particularly fluctuations, due to the beam quality and output of X-ray tubes. As a part of our quality control procedures, we recorded the entrance surface air kerma, tube voltage, and half-value layer measurements made for four diagnost...

  8. Effect of X-ray suppression system upon parameters of electrostatic accelerator ion beam

    Directory of Open Access Journals (Sweden)

    I. G. Ignat'ev

    2014-12-01

    Full Text Available Experimental study results are presented for a beam profile and emittance of an electrostatic accelerator “Sokol” before and after being equipped with magnet X-ray suppression system.

  9. Fourier domain image fusion for differential X-ray phase-contrast breast imaging

    International Nuclear Information System (INIS)

    Coello, Eduardo; Sperl, Jonathan I.; Bequé, Dirk; Benz, Tobias; Scherer, Kai; Herzen, Julia; Sztrókay-Gaul, Anikó; Hellerhoff, Karin; Pfeiffer, Franz; Cozzini, Cristina; Grandl, Susanne

    2017-01-01

    X-Ray Phase-Contrast (XPC) imaging is a novel technology with a great potential for applications in clinical practice, with breast imaging being of special interest. This work introduces an intuitive methodology to combine and visualize relevant diagnostic features, present in the X-ray attenuation, phase shift and scattering information retrieved in XPC imaging, using a Fourier domain fusion algorithm. The method allows to present complementary information from the three acquired signals in one single image, minimizing the noise component and maintaining visual similarity to a conventional X-ray image, but with noticeable enhancement in diagnostic features, details and resolution. Radiologists experienced in mammography applied the image fusion method to XPC measurements of mastectomy samples and evaluated the feature content of each input and the fused image. This assessment validated that the combination of all the relevant diagnostic features, contained in the XPC images, was present in the fused image as well.

  10. Fourier domain image fusion for differential X-ray phase-contrast breast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Coello, Eduardo, E-mail: eduardo.coello@tum.de [GE Global Research, Garching (Germany); Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality, Institut für Informatik, Technische Universität München, Garching (Germany); Sperl, Jonathan I.; Bequé, Dirk [GE Global Research, Garching (Germany); Benz, Tobias [Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality, Institut für Informatik, Technische Universität München, Garching (Germany); Scherer, Kai; Herzen, Julia [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Garching (Germany); Sztrókay-Gaul, Anikó; Hellerhoff, Karin [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich (Germany); Pfeiffer, Franz [Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Garching (Germany); Cozzini, Cristina [GE Global Research, Garching (Germany); Grandl, Susanne [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich (Germany)

    2017-04-15

    X-Ray Phase-Contrast (XPC) imaging is a novel technology with a great potential for applications in clinical practice, with breast imaging being of special interest. This work introduces an intuitive methodology to combine and visualize relevant diagnostic features, present in the X-ray attenuation, phase shift and scattering information retrieved in XPC imaging, using a Fourier domain fusion algorithm. The method allows to present complementary information from the three acquired signals in one single image, minimizing the noise component and maintaining visual similarity to a conventional X-ray image, but with noticeable enhancement in diagnostic features, details and resolution. Radiologists experienced in mammography applied the image fusion method to XPC measurements of mastectomy samples and evaluated the feature content of each input and the fused image. This assessment validated that the combination of all the relevant diagnostic features, contained in the XPC images, was present in the fused image as well.

  11. X-ray section topographs under various coherence properties of the primary beam

    International Nuclear Information System (INIS)

    Borowski, J.; Gronkowski, J.

    2001-01-01

    The aim of this work is to study to what extent a typical section-topography setup can supply information about the degree of coherence of the incident x-ray beam. In real experiments, the incident beam is partially coherent, with the degree of coherence described by the shape of the correlation function. In this paper the correlation functions for the outgoing beam are calculated by solving the Takagi-Taupin equations, assuming a truncated Gauss correlation function for the incident beam with the correlation length determined by the van Cittert-Zernike theorem. Its influence on the measured intensity of the diffracted beam in section topography is investigated. (author)

  12. X-ray diffraction imaging of material microstructures

    KAUST Repository

    Varga, Laszlo

    2016-10-20

    Various examples are provided for x-ray imaging of the microstructure of materials. In one example, a system for non-destructive material testing includes an x-ray source configured to generate a beam spot on a test item; a grid detector configured to receive x- rays diffracted from the test object; and a computing device configured to determine a microstructure image based at least in part upon a diffraction pattern of the x-rays diffracted from the test object. In another example, a method for determining a microstructure of a material includes illuminating a beam spot on the material with a beam of incident x-rays; detecting, with a grid detector, x-rays diffracted from the material; and determining, by a computing device, a microstructure image based at least in part upon a diffraction pattern of the x-rays diffracted from the material.

  13. Spectroscopic analysis and dosimetry of diagnostic x-ray beams filtered by rare earth materials

    International Nuclear Information System (INIS)

    Tyndall, D.A.

    1986-01-01

    A laboratory investigation was carried out to assess the effect of various types of rare earth filter materials on the energy spectrum and concomitant reduced exposure values of diagnostic x-ray beams at 70, 80, and 90 kVp. An x-ray spectroscope was constructed and used to generate the energy spectra of beams passing through the various rare earth filter materials. Photographs were made of each spectrum, and live-time gross photon counts were recorded. Following spectral determinations, ionization chamber readings were generated for each filter material. Substantial effects on x-ray spectra and reduction of exposure values were noted. The degree of these effects were dependent on the atomic number, k-edge, and thickness of each filter. Metallic forms of rare earth materials proved to be more effective than the salt forms with erbium offering the greatest potential for reduction in exposures over the range of experimental kilovolt (peak) values

  14. X-Ray Beam Studies of Charge Sharing in Small Pixel, Spectroscopic, CdZnTe Detectors

    Science.gov (United States)

    Allwork, Christopher; Kitou, Dimitris; Chaudhuri, Sandeep; Sellin, Paul J.; Seller, Paul; Veale, Matthew C.; Tartoni, Nicola; Veeramani, Perumal

    2012-08-01

    Recent advances in the growth of CdZnTe material have allowed the development of small pixel, spectroscopic, X-ray imaging detectors. These detectors have applications in a diverse range of fields such as medical, security and industrial sectors. As the size of the pixels decreases relative to the detector thickness, the probability that charge is shared between multiple pixels increases due to the non zero width of the charge clouds drifting through the detector. These charge sharing events will result in a degradation of the spectroscopic performance of detectors and must be considered when analyzing the detector response. In this paper charge sharing and charge loss in a 250 μm pitch CdZnTe pixel detector has been investigated using a mono-chromatic X-ray beam at the Diamond Light Source, U.K. Using a 20 μm beam diameter the detector response has been mapped for X-ray energies both above (40 keV) and below (26 keV) the material K-shell absorption energies to study charge sharing and the role of fluorescence X-rays in these events.

  15. A Monte Carlo approach for simulating the propagation of partially coherent x-ray beams

    DEFF Research Database (Denmark)

    Prodi, A.; Bergbäck Knudsen, Erik; Willendrup, Peter Kjær

    2011-01-01

    Advances at SR sources in the generation of nanofocused beams with a high degree of transverse coherence call for effective techniques to simulate the propagation of partially coherent X-ray beams through complex optical systems in order to characterize how coherence properties such as the mutual...

  16. Ultra-short wavelength x-ray system

    Science.gov (United States)

    Umstadter, Donald [Ann Arbor, MI; He, Fei [Ann Arbor, MI; Lau, Yue-Ying [Potomac, MD

    2008-01-22

    A method and apparatus to generate a beam of coherent light including x-rays or XUV by colliding a high-intensity laser pulse with an electron beam that is accelerated by a synchronized laser pulse. Applications include x-ray and EUV lithography, protein structural analysis, plasma diagnostics, x-ray diffraction, crack analysis, non-destructive testing, surface science and ultrafast science.

  17. Generalized algorithm for X-ray projections generation in cone-beam tomography

    International Nuclear Information System (INIS)

    Qin Zhongyuan; Mu Xuanqin; Wang Ping; Cai Yuanlong; Hou Chuanjian

    2002-01-01

    In order to get rid of random factors in the measurement so as to support proceeding 3D reconstruction, a general approach is presented to obtain the X-ray projections in cone-beam tomography. The phantom is firstly discretized into cubic volume through inverse transformation then a generalized projection procedure is proposed to the digitized result without concerning what the phantom exactly is. In the second step, line integrals are calculated to obtain the projection of each X-ray through accumulation of tri-linear interpolation. Considering projection angles, a rotation matrix is proposed to the X-ray source and the detector plane so projections in arbitrary angles can be got. In this approach the algorithm is easy to be extended and irregular objects can also be processed. The algorithm is implemented in Visual C++ and experiments are done using different models. Satisfactory results are obtained. It makes good preparation for the proceeding reconstruction

  18. Analysis on breast X-ray of chronic schizophrenia and Iiterature review

    International Nuclear Information System (INIS)

    Dang Lianrong; Wang Xuqiang; Xie Junwei; Pei Genxiang

    2008-01-01

    Objective: To research the symptom of breast X-ray of chronic schizophrenia and the influence of its clinical features. Methods: Take 50 patients who have been under treatment in our hospital for over 5 years as sample of psychotic group and same number of healthy people as control group. Analyze their X-ray films, using statistics to deal with their lung area of both before and after 5 years. Evaluation Criteria of X-ray: (1) Double layer rise; (2)Single or double lung base subsegmental atelectasis; (3)Heart drown; (4)Heart turing with the heart apex extending to the left; (5)The double lung bottom have gathering stripes; (6)The upper layer have wider shadow. Results: The lung lobes of the patient group become smaller than they were 5 years ago. Data show great difference between two years (t=6.7099, P<0.01). The lung lobes of psychotic group become bigger than the control group in the first X-ray films (t=2.025, P<0.05), but smaller in the last X-ray films (t=5.512, P<0.01). Among them, 37 cases show double layer rise; 19 cases show single or double lung base subsegmental atelectasis; 24 cases show heart drown; 19 cases show heart turing and heart apex extending to the left; 37 cases show double lung bottom gathering stripes; 17 cases show wider shadow. Conclusion: Morphology and pathology changes of schizophrenia patients are related to the side effect of anti-schizophrenia medicine and endocrine disorders. (authors)

  19. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... evaluation. National and international radiology protection organizations continually review and update the technique standards used by radiology professionals. Modern x-ray systems have very controlled x-ray beams and dose ...

  20. Characterization of a Test for Invasive Breast Cancer Using X-ray Diffraction of Hair - Results of a Clinical Trial

    Directory of Open Access Journals (Sweden)

    Gary L. Corino

    2009-11-01

    Full Text Available Objective: To assess the performance of a test for breast cancer utilizing synchrotron x-ray diffraction analysis of scalp hair from women undergoing diagnostic radiology assessment. Design and Setting: A double-blinded clinical trial of women who attended diagnostic radiology clinics in Australia. Patients: 1796 women referred for diagnostic radiology, with no previous history of cancer. Main Outcome Measures: Sensitivity, specificity and accuracy of the hair test analysis compared to the gold standard of imaging followed by biopsy where indicated. Results: The hair-based assay had an overall accuracy of >77% and a negative predictive value of 99%. For all women, the sensitivity of both mammography and x-ray diffraction alone was 64%, but when used together the sensitivity rose to 86%. The sensitivity of the hair test for women under the age of 70 was 74%. Conclusion: In this large population trial the association between the presence of breast cancer and an altered hair fibre X-ray diffraction pattern previously reported has been confirmed. It appears that mammography and X-ray diffraction of hair detect different populations of breast cancers, and are synergistic when used together.

  1. X-ray beam penetration in TXRF measurement of polycrystalline and amorphous surfaces

    International Nuclear Information System (INIS)

    Ghatak-Roy, A.R.; Hossain, T.Z.

    2000-01-01

    For TXRF measurement on single crystal silicon surface, it is generally agreed that the x-ray beam penetration is of the order of a few hundred Angstroms from the surface. However, for polycrystalline and amorphous surfaces - frequently used in semiconductor manufacturing there are evidences that x-rays penetrate much deeper revealing underlying layers. The evidences come from various measurements done with films such as silicon dioxide, silicon nitride and metal films such as aluminum, titanium and cobalt. A systematic study was carried out to help understand the issue further. Four sets of samples (on 8 inch wafers) were prepared to create layers buried under various deposited metal and non-metal layers. The metal layers created were aluminum, titanium and cobalt and the non-metal layers were silicon dioxide and silicon nitride. These samples were analyzed by TXRF under various angles and energies and the data were analyzed for signals from various buried layers along with their angular dependence. The results indicated deep penetration of x-ray beams. The samples were further analyzed by SIMS (Secondary Ion Mass Spectrometry) and some of them by ICP-MS (Inductively Coupled Plasma - Mass Spectrometry) to obtain information about their depth profiles. This was done in order to rule out the possibility of intermixing of layers during deposition. (author)

  2. Fluorescence detection of white-beam X-ray absorption anisotropy: towards element-sensitive projections of local atomic structure

    International Nuclear Information System (INIS)

    Korecki, P.; Tolkiehn, M.; Dąbrowski, K. M.; Novikov, D. V.

    2011-01-01

    A method for a direct measurement of X-ray projections of the atomic structure is described. Projections of the atomic structure around Nb atoms in a LiNbO 3 single crystal were obtained from a white-beam X-ray absorption anisotropy pattern detected using Nb K fluorescence. Projections of the atomic structure around Nb atoms in a LiNbO 3 single crystal were obtained from a white-beam X-ray absorption anisotropy (XAA) pattern detected using Nb K fluorescence. This kind of anisotropy results from the interference of X-rays inside a sample and, owing to the short coherence length of a white beam, is visible only at small angles around interatomic directions. Consequently, the main features of the recorded XAA corresponded to distorted real-space projections of dense-packed atomic planes and atomic rows. A quantitative analysis of XAA was carried out using a wavelet transform and allowed well resolved projections of Nb atoms to be obtained up to distances of 10 Å. The signal of nearest O atoms was detected indirectly by a comparison with model calculations. The measurement of white-beam XAA using characteristic radiation indicates the possibility of obtaining element-sensitive projections of the local atomic structure in more complex samples

  3. Characterization of low energy X-rays beams with an extrapolation chamber

    International Nuclear Information System (INIS)

    Bastos, Fernanda Martins

    2015-01-01

    In laboratories involving Radiological Protection practices, it is usual to use reference radiations for calibrating dosimeters and to study their response in terms of energy dependence. The International Organization for Standardization (ISO) established four series of reference X-rays beams in the ISO- 4037 standard: the L and H series, as low and high air Kerma rates, respectively, the N series of narrow spectrum and W series of wide spectrum. The X-rays beams with tube potential below 30 kV, called 'low energy beams' are, in most cases, critical as far as the determination of their parameters for characterization purpose, such as half-value layer. Extrapolation chambers are parallel plate ionization chambers that have one mobile electrode that allows variation of the air volume in its interior. These detectors are commonly used to measure the quantity Absorbed Dose, mostly in the medium surface, based on the extrapolation of the linear ionization current as a function of the distance between the electrodes. In this work, a characterization of a model 23392 PTW extrapolation chamber was done in low energy X-rays beams of the ISO- 4037 standard, by determining the polarization voltage range through the saturation curves and the value of the true null electrode spacing. In addition, the metrological reliability of the extrapolation chamber was studied with measurements of the value of leakage current and repeatability tests; limit values were established for the proper use of the chamber. The PTW23392 extrapolation chamber was calibrated in terms of air Kerma in some of the ISO radiation series of low energy; the traceability of the chamber to the National Standard Dosimeter was established. The study of energy dependency of the extrapolation chamber and the assessment of the uncertainties related to the calibration coefficient were also done; it was shown that the energy dependence was reduced to 4% when the extrapolation technique was used. Finally, the first

  4. Influence of beam divergence on form-factor in X-ray diffraction radiation

    International Nuclear Information System (INIS)

    Sergeeva, D.Yu.; Tishchenko, A.A.; Strikhanov, M.N.

    2015-01-01

    Diffraction radiation from divergent beam is considered in terms of radiation in UV and X-ray range. Scedastic form of Gaussian distribution of the particle in the bunch, i.e. Gaussian distribution with changing dispersion has been used, which is more adequate for description of divergent beams than often used Gaussian distribution with constant dispersion. Both coherent and incoherent form-factors are taken into account. The conical diffraction effect in diffraction radiation is proved to make essential contribution in spectral-angular characteristics of radiation from a divergent beam

  5. Pin-photodiode array for the measurement of fan-beam energy and air kerma distributions of X-ray CT scanners.

    Science.gov (United States)

    Haba, Tomonobu; Koyama, Shuji; Aoyama, Takahiko; Kinomura, Yutaka; Ida, Yoshihiro; Kobayashi, Masanao; Kameyama, Hiroshi; Tsutsumi, Yoshinori

    2016-07-01

    Patient dose estimation in X-ray computed tomography (CT) is generally performed by Monte Carlo simulation of photon interactions within anthropomorphic or cylindrical phantoms. An accurate Monte Carlo simulation requires an understanding of the effects of the bow-tie filter equipped in a CT scanner, i.e. the change of X-ray energy and air kerma along the fan-beam arc of the CT scanner. To measure the effective energy and air kerma distributions, we devised a pin-photodiode array utilizing eight channels of X-ray sensors arranged at regular intervals along the fan-beam arc of the CT scanner. Each X-ray sensor consisted of two plate type of pin silicon photodiodes in tandem - front and rear photodiodes - and of a lead collimator, which only allowed X-rays to impinge vertically to the silicon surface of the photodiodes. The effective energy of the X-rays was calculated from the ratio of the output voltages of the photodiodes and the dose was calculated from the output voltage of the front photodiode using the energy and dose calibration curves respectively. The pin-photodiode array allowed the calculation of X-ray effective energies and relative doses, at eight points simultaneously along the fan-beam arc of a CT scanner during a single rotation of the scanner. The fan-beam energy and air kerma distributions of CT scanners can be effectively measured using this pin-photodiode array. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  6. Development of high-resolution x-ray CT system using parallel beam geometry

    Energy Technology Data Exchange (ETDEWEB)

    Yoneyama, Akio, E-mail: akio.yoneyama.bu@hitachi.com; Baba, Rika [Central Research Laboratory, Hitachi Ltd., Hatoyama, Saitama (Japan); Hyodo, Kazuyuki [Institute of Materials Science, High Energy Accelerator Research Organization, Tsukuba, Ibaraki (Japan); Takeda, Tohoru [School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa (Japan); Nakano, Haruhisa; Maki, Koutaro [Department of Orthodontics, School of Dentistry Showa University, Ota-ku, Tokyo (Japan); Sumitani, Kazushi; Hirai, Yasuharu [Kyushu Synchrotron Light Research Center, Tosu, Saga (Japan)

    2016-01-28

    For fine three-dimensional observations of large biomedical and organic material samples, we developed a high-resolution X-ray CT system. The system consists of a sample positioner, a 5-μm scintillator, microscopy lenses, and a water-cooled sCMOS detector. Parallel beam geometry was adopted to attain a field of view of a few mm square. A fine three-dimensional image of birch branch was obtained using a 9-keV X-ray at BL16XU of SPring-8 in Japan. The spatial resolution estimated from the line profile of a sectional image was about 3 μm.

  7. X-ray Radiation Mechanisms and the Beaming Effect of Hot Spots ...

    Indian Academy of Sciences (India)

    Astr. (2011) 32, 193–196 c Indian Academy of Sciences. X-ray Radiation Mechanisms and the Beaming Effect of Hot Spots and Knots in AGN Jets. Jin Zhang1,∗. , Jin-Ming Bai2, Liang Chen2 & Enwei Liang3. 1College of Physics and Electronic Engineering, Guangxi Teachers Education University,. Nanning 530001, China.

  8. Thermometric- and Acoustic-Based Beam Power Monitor for Ultra-Bright X-Rays

    International Nuclear Information System (INIS)

    2010-01-01

    A design for an average beam power monitor for ultra-bright X-ray sources is proposed that makes simultaneous use of calorimetry and radiation acoustics. Radiation incident on a solid target will induce heating and ultrasonic vibrations, both of which may be measured to give a fairly precise value of the beam power. The monitor is intended for measuring ultra-bright Free-Electron Laser (FEL) X-ray beams, for which traditional monitoring technologies such as photo-diodes or scintillators are unsuitable. The monitor consists of a Boron Carbide (B 4 C) target designed to absorb most of the incident beam's energy. Resistance temperature detectors (RTD) and piezoelectric actuators are mounted on the outward faces of the target to measure the temperature changes and ultrasonic vibrations induced by the incident beam. The design was tested using an optical pulsed beam (780 nm, 120 and 360 Hz) from a Ti:sapphire oscillator at several energies between 0.8 and 2.6 mJ. The RTDs measured an increase in temperature of about 10 K over a period of several minutes. The piezoelectric sensors recorded ringing acoustic oscillations at 580 ± 40 kHz. Most importantly, the amplitude of the acoustic signals was observed to scale linearly with beam power up to 2 mJ of pulse energy. Above this pulse energy, the vibrational signals became nonlinear. Several causes for this nonlinearity are discussed, including amplifier saturation and piezoelectric saturation. Despite this nonlinearity, these measurements demonstrate the feasibility of such a beam power measurement device. The advantage of two distinct measurements (acoustic and thermometric) provides a useful method of calibration that is unavailable to current LCLS diagnostics tools.

  9. Synchrotron radiation X-ray microfluorescence techniques

    Indian Academy of Sciences (India)

    Synchrotron X-ray imaging systems with fluorescence techniques was developed for biomedical researches in Brazilian Synchrotron Laboratory. An X-ray fluorescence microtomography system was implemented to analyse human prostate and breast samples and an X-ray microfluorescence system was implemented to ...

  10. Measurement of high energy x-ray beam penumbra with Gafchromic trade mark sign EBT radiochromic film

    International Nuclear Information System (INIS)

    Cheung Tsang; Butson, Martin J.; Yu, Peter K. N.

    2006-01-01

    High energy x-ray beam penumbra are measured using Gafchromic trade mark sign EBT film. Gafchromic trade mark sign EBT, due to its limited energy dependence and high spatial resolution provide a high level of accuracy for dose assessment in penumbral regions. The spatial resolution of film detector systems is normally limited by the scanning resolution of the densitometer. Penumbral widths (80%/20%) measured at D max were found to be 2.8, 3.0, 3.2, and 3.4 mm (±0.2 mm) using 5, 10, 20, and 30 cm square field sizes, respectively, for a 6 MV linear accelerator produced x-ray beam. This is compared to 3.2 mm±0.2 mm (Kodak EDR2) and 3.6 mm±0.2 mm (Kodak X-Omat V) at 10 cmx10 cm measured using radiographic film. Using a zero volume extrapolation technique for ionization chamber measurements, the 10 cmx10 cm field penumbra at D max was measured to be 3.1 mm, a close match to Gafchromic trade mark sign EBT results. Penumbral measurements can also be made at other depths, including the surface, as the film does not suffer significantly from dosimetric variations caused by changing x-ray energy spectra. Gafchromic trade mark sign EBT film provides an adequate measure of penumbral dose for high energy x-ray beams

  11. Spectrometry of X-ray beams using Cadmium and Zinc Teluride detector

    International Nuclear Information System (INIS)

    Becker, Paulo Henriques Bastos

    1997-06-01

    Determination of X-ray spectra to be utilized for medical diagnostics is a complementary process to the development of procedures to be applied to the quality control of radiodiagnostics X-ray equipment. Until some years ago, that was only possible using Germanium or Silicon detectors. Both have an excellent resolution in this energy range, but present also some restrictions as there are high costs and the necessity of operating them at temperature of liquid Nitrogen, which is not always available at the measurement's place. Room temperature detectors like Cadmium Telluride and Mercury Iodine don't have these restrictions. They, however, have a lower resolution and incomplete collection of the charges produced by their interaction with radiation. With technological advance of crystal growth in general and new techniques like cooling the crystal with a Peltier cell and rise time discrimination circuits, today Cadmium Telluride detectors show a resolution very close to that from Germanium detectors. This work relates to the routine use of Cadmium and Zinc Telluride detectors for measuring X-ray spectra in loco of diagnostic X-ray units. It characterizes the properties of a commercially available detector and offers a model for stripping the measured pulse height distribution. It was also developed a collimator to allow the direct measurement of the beam. The model developed and the constructed set-up were applied to two X-ray tubes and the achieved spectra compared with some spectra available from the literature. (author)

  12. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... changes seen in metabolic conditions. assist in the detection and diagnosis of bone cancer . locate foreign objects ... standards used by radiology professionals. Modern x-ray systems have very controlled x-ray beams and dose ...

  13. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... current x-ray images for diagnosis and disease management. top of page How is the procedure performed? ... have very controlled x-ray beams and dose control methods to minimize stray (scatter) radiation. This ensures ...

  14. Polycapillary x-ray optics for macromolecular crystallography

    International Nuclear Information System (INIS)

    Owens, S.M.; Gibson, W.M.; Carter, D.C.; Sisk, R.C.; Ho, J.X.

    1996-01-01

    Polycapillary x-ray optics have found potential application in many different fields, including antiscatter and magnification in mammography, radiography, x-ray fluorescence, x-ray lithography, and x-ray diffraction techniques. In x-ray diffraction, an optic is used to collect divergent x-rays from a point source and redirect them into a quasi-parallel, or slightly focused beam. Monolithic polycapillary optics have been developed recently for macromolecular crystallography and have already shown considerable gains in diffracted beam intensity over pinhole collimation. Development is being pursued through a series of simulations and prototype optics. Many improvements have been made over the stage 1 prototype reported previously, which include better control over the manufacturing process, reducing the diameter of the output beam, and addition of a slight focusing at the output of the optic to further increase x-ray flux at the sample. The authors report the characteristics and performance of the stage 1 and stage 2 optics

  15. Beam hardening: Analytical considerations of the effective attenuation coefficient of x-ray tomography

    International Nuclear Information System (INIS)

    Alles, J.; Mudde, R. F.

    2007-01-01

    Polychromatic x-ray beams traveling though material are prone to beam hardening, i.e., the high energy part of the incident spectrum gets over represented when traveling farther into the material. This study discusses the concept of a mean attenuation coefficient in a formal way. The total energy fluence is one-to-one related to the traveled distance in case of a polychromatic beam moving through a given, inhomogeneous material. On the basis of this one-to-one relation, it is useful to define a mean attenuation coefficient and study its decrease with depth. Our results are based on a novel parametrization of the energy dependence of the attenuation coefficient that allows for closed form evaluation of certain spectral integrals. This approach underpins the ad hoc semianalytical expressions given in the literature. An analytical model for the average attenuation coefficient is proposed that uses a simple fit of the attenuation coefficient as a function of the photon energy as input. It is shown that a simple extension of this model gives a rather good description of beam hardening for x-rays traveling through water

  16. Carbon ion beam is more effective to induce cell death in sphere-type A172 human glioblastoma cells compared with X-rays.

    Science.gov (United States)

    Takahashi, Momoko; Hirakawa, Hirokazu; Yajima, Hirohiko; Izumi-Nakajima, Nakako; Okayasu, Ryuichi; Fujimori, Akira

    2014-12-01

    To obtain human glioblastoma cells A172 expressing stem cell-related protein and comparison of radiosensitivity in these cells with X-rays and carbon beam. Human monolayer-type A172 glioblastoma cells were maintained in normal medium with 10% bovine serum. In order to obtain sphere-type A172 cells the medium was replaced with serum-free medium supplemented with growth factors. Both types of A172 cells were irradiated with either X-rays or carbon ion beams and their radiosensitivity was evaluated. Serum-free medium induced expression of stem cell-related proteins in A172 cells along with the neurosphere-like appearance. These sphere-type cells were found resistant to both X-rays and carbon ion beams. Phosphorylation of histone H2A family member X persisted for a longer period in the cells exposed to carbon ion beams than in those exposed to X-rays and it disappeared quicker in the sphere type than in the monolayer type. Relative radioresistance of the sphere type cells was smaller for carbon ion beams than for X-rays. We demonstrated that glioblastoma A172 cells with induced stem cell-related proteins turned resistant to irradiation. Accelerated heavy ion particles may have advantage over X-rays in overcoming the tumor resistance due to cell stemness.

  17. Pulse-periodic generation of supershort avalanche electron beams and X-ray emission

    Science.gov (United States)

    Baksht, E. Kh.; Burachenko, A. G.; Erofeev, M. V.; Tarasenko, V. F.

    2014-05-01

    Pulse-periodic generation of supershort avalanche electron beams (SAEBs) and X-ray emission in nitrogen, as well as the transition from a single-pulse mode to a pulse-periodic mode with a high repetition frequency, was studied experimentally. It is shown that, in the pulse-periodic mode, the full width at halfmaximum of the SAEB is larger and the decrease rate of the gap voltage is lower than those in the single-pulse mode. It is found that, when the front duration of the voltage pulse at a nitrogen pressure of 90 Torr decreases from 2.5 to 0.3 ns, the X-ray exposure dose in the pulse-periodic mode increases by more than one order of magnitude and the number of SAEB electrons also increases. It is shown that, in the pulse-periodic mode of a diffuse discharge, gas heating in the discharge gap results in a severalfold increase in the SAEB amplitude (the number of electrons in the beam). At a generator voltage of 25 kV, nitrogen pressure of 90 Torr, and pulse repetition frequency of 3.5 kHz, a runaway electron beam was detected behind the anode foil.

  18. X-ray generator

    Energy Technology Data Exchange (ETDEWEB)

    Zucarias, A; Shepherd, J W

    1982-09-08

    An X-ray tube has a tubular envelope with a cathode for directing an electron beam onto a focal spot area of a spaced anode target to generate X-rays. The target is mounted for axial rotation on one end of a rotor disposed in an end portion of the envelope and encircled by a stator of an alternating current induction motor. An annular shield of high permeability magnetic material extends transversely between the electron beam and the stator of the induction motor for shunting stray or fringe electromagnetic fields established by the stator away from the electron beam to avoid consequent lateral deflections of the electron and corresponding lateral movements of the focal spot area.

  19. Dental X-ray apparatus

    International Nuclear Information System (INIS)

    Weiss, M.E.

    1980-01-01

    Intra-oral X-ray apparatus which reduces the number of exposures necessary to obtain panoramic dental radiographs is described in detail. It comprises an electron gun, a tubular target carrier projecting from the gun along the beam axis and carrying at its distal end a target surrounded by a shield of X-ray opaque material. This shield extends forward and laterally of the target and has surfaces which define a wedge or cone-shaped radiation pattern delimited vertically by the root tips of the patient's teeth. A film holder is located externally of the patient's mouth. A disposable member can fit on the target carrier to depress the patient's tongue out of the radiation pattern and to further shield the roof of the mouth. The electron beam can be magnetically deflected to change the X-ray beam direction. (author)

  20. Indications for and comparative diagnostic value of combined ultrasound and X-ray mammography

    International Nuclear Information System (INIS)

    Novak, D.

    1983-01-01

    A standardised method of ultrasound mammography is described. In order to achieve the same position, form, and shape of the breast as during roentgen mammography a Lucite plate in horizontal, and vertical position us used. Ultrasound contact scanning of the whole breast is carried out in cranio-caudal as well as in medio-lateral direction of the ultrasound beam. Ultrasound scanning is performed with the compression of the breast corresponding to the compression during roentgen mammography. It was found that the ultrasound breast examination combined with X-ray mammography optimizes the differentiation between benign and malignant masses and therefore may reduce the incidence of breast biopsy. A combined use of both examination modalities in the evaluation of the breast is advocated. (orig.)

  1. Radiation exposure to foetus and breasts from dental X-ray examinations: effect of lead shields.

    Science.gov (United States)

    Kelaranta, Anna; Ekholm, Marja; Toroi, Paula; Kortesniemi, Mika

    2016-01-01

    Dental radiography may involve situations where the patient is known to be pregnant or the pregnancy is noticed after the X-ray procedure. In such cases, the radiation dose to the foetus, though low, needs to be estimated. Uniform and widely used guidance on dental X-ray procedures during pregnancy are presently lacking, the usefulness of lead shields is unclear and practices vary. Upper estimates of radiation doses to the foetus and breasts of the pregnant patient were estimated with an anthropomorphic female phantom in intraoral, panoramic, cephalometric and CBCT dental modalities with and without lead shields. The upper estimates of foetal doses varied from 0.009 to 6.9 μGy, and doses at the breast level varied from 0.602 to 75.4 μGy. With lead shields, the foetal doses varied from 0.005 to 2.1 μGy, and breast doses varied from 0.002 to 10.4 μGy. The foetal dose levels without lead shielding were dental radiographic examination.

  2. X-ray-ultraviolet beam splitters for the Michelson interferometer

    International Nuclear Information System (INIS)

    Delmotte, Franck; Ravet, Marie-Francoise; Bridou, Francoise; Varniere, Francoise; Zeitoun, Philippe; Hubert, Sebastien; Vanbostal, Laurent; Soullie, Gerard

    2002-01-01

    With the aim of realizing a Michelson interferometer working at 13.9 nm, we have developed a symmetrical beam splitter with multilayers deposited on the front and back sides of a silicon nitride membrane. On the basis of the experimental optical properties of the membrane, simulations have been performed to define the multilayer structure that provides the highest reflectivity-transmission product. Optimized Mo-Si multilayers have been successfully deposited on both sides of the membrane by use of the ion-beam sputtering technique, with a thickness-period reproducibility of 0.1 nm. Measurements by means of synchrotron radiation at 13.9 nm and at an angle of 45 deg. provide a reflectivity of 14.2% and a transmission of 15.2% for a 60% s-polarized light, close to the simulated values. Such a beam splitter has been used for x-ray laser Michelson interferometry at 13.9 nm. The first interferogram is discussed

  3. X-ray-ultraviolet beam splitters for the Michelson interferometer.

    Science.gov (United States)

    Delmotte, Franck; Ravet, Marie-Françoise; Bridou, Françoise; Varnière, Françoise; Zeitoun, Philippe; Hubert, Sébastien; Vanbostal, Laurent; Soullie, Gérard

    2002-10-01

    With the aim of realizing a Michelson interferometer working at 13.9 nm, we have developed a symmetrical beam splitter with multilayers deposited on the front and back sides of a silicon nitride membrane. On the basis of the experimental optical properties of the membrane, simulations have been performed to define the multilayer structure that provides the highest reflectivity-transmission product. Optimized Mo-Si multilayers have been successfully deposited on both sides of t he membrane by use of the ion-beam sputtering technique, with a thickness-period reproducibility of 0.1 nm. Measurements by means of synchrotron radiation at 13.9 nm and at an angle of 45 degrees provide a reflectivity of 14.2% and a transmission of 15.2% for a 60% s-polarized light, close to the simulated values. Such a beam splitter has been used for x-ray laser Michelson interferometry at 13.9 nm. The first interferogram is discussed.

  4. Calibration of the Gamma-RAy Polarimeter Experiment (GRAPE) at a polarized hard X-ray beam

    International Nuclear Information System (INIS)

    Bloser, P.F.; Legere, J.S.; McConnell, M.L.; Macri, J.R.; Bancroft, C.M.; Connor, T.P.; Ryan, J.M.

    2009-01-01

    The Gamma-RAy Polarimeter Experiment (GRAPE) is a concept for an astronomical hard X-ray Compton polarimeter operating in the 50-500 keV energy band. The instrument has been optimized for wide-field polarization measurements of transient outbursts from energetic astrophysical objects such as gamma-ray bursts and solar flares. The GRAPE instrument is composed of identical modules, each of which consists of an array of scintillator elements read out by a multi-anode photomultiplier tube (MAPMT). Incident photons Compton scatter in plastic scintillator elements and are subsequently absorbed in inorganic scintillator elements; a net polarization signal is revealed by a characteristic asymmetry in the azimuthal scattering angles. We have constructed a prototype GRAPE module containing a single CsI(Na) calorimeter element, at the center of the MAPMT, surrounded by 60 plastic elements. The prototype has been combined with custom readout electronics and software to create a complete 'engineering model' of the GRAPE instrument. This engineering model has been calibrated using a nearly 100% polarized hard X-ray beam at the Advanced Photon Source at Argonne National Laboratory. We find modulation factors of 0.46±0.06 and 0.48±0.03 at 69.5 and 129.5 keV, respectively, in good agreement with Monte Carlo simulations. In this paper we present details of the beam test, data analysis, and simulations, and discuss the implications of our results for the further development of the GRAPE concept.

  5. Combined optic system based on polycapillary X-ray optics and single-bounce monocapillary optics for focusing X-rays from a conventional laboratory X-ray source

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Xuepeng; Liu, Zhiguo [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Sun, Tianxi, E-mail: stx@bnu.edu.cn [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Yi, Longtao; Sun, Weiyuan; Li, Fangzuo; Jiang, Bowen [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Ma, Yongzhong [Center for Disease Control and Prevention of Beijing, Beijing 100013 (China); Ding, Xunliang [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2015-12-01

    Two combined optic systems based on polycapillary X-ray optics and single-bounce monocapillary optics (SBMO) were designed for focusing the X-rays from a conventional laboratory X-ray source. One was based on a polycapillary focusing X-ray lens (PFXRL) and a single-bounce ellipsoidal capillary (SBEC), in which the output focal spot with the size of tens of micrometers of the PFXRL was used as the “virtual” X-ray source for the SBEC. The other system was based on a polycapillary parallel X-ray lens (PPXRL) and a single-bounce parabolic capillary (SBPC), in which the PPXRL transformed the divergent X-ray beam from an X-ray source into a quasi-parallel X-ray beam with the divergence of sever milliradians as the incident illumination of the SBPC. The experiment results showed that the combined optic systems based on PFXRL and SBEC with a Mo rotating anode X-ray generator with the focal spot with a diameter of 300 μm could obtain a focal spot with the total gain of 14,300 and focal spot size of 37.4 μm, and the combined optic systems based on PPXRL and SBPC with the same X-ray source mentioned above could acquire a focal spot with the total gain of 580 and focal spot size of 58.3 μm, respectively. The two combined optic systems have potential applications in micro X-ray diffraction, micro X-ray fluorescence, micro X-ray absorption near edge structure, full field X-ray microscopes and so on.

  6. Dynamical x-ray diffraction studies of interfacial strain in superlattices grown by molecular beam epitaxy

    International Nuclear Information System (INIS)

    Vandenberg, J.M.; Chu, S.N.G.; Hamm, R.A.; Panish, M.B.; Ritter, D.; Mancrander, A.T.

    1992-01-01

    This paper reports on dynamical X-ray diffraction studies that have been carried out for lattice-matched InGaAs/InP superlattices grown by modified molecular beam epitaxy (MBE) techniques. The (400) X-ray satellite pattern, which is predominantly affected by the strain modulation, was analyzed. The strain and thickness of the actual layers including the presence of strained interfacial regions were determined

  7. Development of isodose curves for A 6 mv x-ray beam

    Energy Technology Data Exchange (ETDEWEB)

    Hidaytalla, Lamya Abbas [Department of Physics, Faculty of Science, University of Khartoum, Khartoum (Sudan)

    1994-08-01

    In this thesis radiation distribution of 6 Mv x-ray beam in a water phantom is developed. The method is based on a simple empirical equation and the assumption that the x-ray source is a point source. This leads to a simple equation for the calculation and plotting of the isodose curves. the charts obtained for two fields, 6*6 and 12*12 cm{sup 2} show good agreement with the previous data used in the isotope and radiation centre, Khartoum hospital. It is suggested that further development should be carried out by writing a computer program for all the fields. (Author) 14 refs. , 9 tabs. , 34 figs. Also available from the Department of Physics, Faculty of Science, University of Khartoum, Khartoum (SD)

  8. Optimum filter selection for Dual Energy X-ray Applications through Analytical Modeling

    International Nuclear Information System (INIS)

    Koukou, V; Martini, N; Sotiropoulou, P; Nikiforidis, G; Michail, C; Kalyvas, N; Kandarakis, I; Fountos, G

    2015-01-01

    In this simulation study, an analytical model was used in order to determine the optimal acquisition parameters for a dual energy breast imaging system. The modeled detector system, consisted of a 33.91mg/cm 2 Gd 2 O 2 S:Tb scintillator screen, placed in direct contact with a high resolution CMOS sensor. Tungsten anode X-ray spectra, filtered with various filter materials and filter thicknesses were examined for both the low- and high-energy beams, resulting in 3375 combinations. The selection of these filters was based on their K absorption edge (K-edge filtering). The calcification signal-to-noise ratio (SNR tc ) and the mean glandular dose (MGD) were calculated. The total mean glandular dose was constrained to be within acceptable levels. Optimization was based on the maximization of the SNR tc /MGD ratio. The results showed that the optimum spectral combination was 40kVp with added beam filtration of 100 μm Ag and 70kVp Cu filtered spectrum of 1000 μm for the low- and high-energy, respectively. The minimum detectable calcification size was 150 μm. Simulations demonstrate that this dual energy X-ray technique could enhance breast calcification detection. (paper)

  9. Measurement of conversion coefficients between air Kerma and personal dose equivalent and backscatter factors for diagnostic X-ray beams

    International Nuclear Information System (INIS)

    Rosado, Paulo Henrique Goncalves

    2008-01-01

    Two sets of quantities are import in radiological protection: the protection and operational quantities. Both sets can be related to basic physical quantities such as kerma through conversion coefficients. For diagnostic x-ray beams the conversion coefficients and backscatter factors have not been determined yet, those parameters are need for calibrating dosimeters that will be used to determine the personal dose equivalent or the entrance skin dose. Conversion coefficients between air kerma and personal dose equivalent and backscatter factors were experimentally determined for the diagnostic x-ray qualities RQR and RQA recommended by the International Electrotechnical Commission (IEC). The air kerma in the phantom and the mean energy of the spectrum were measured for such purpose. Harshaw LiF-100H thermoluminescent dosemeters (TLD) were used for measurements after being calibrated against an 180 cm 3 Radcal Corporation ionization chamber traceable to a reference laboratory. A 300 mm x 300 mm x 150 mm polymethylmethacrylate (PMMA) slab phantom was used for deep-dose measurements. Tl dosemeters were placed in the central axis of the x-ray beam at 5, 10, 15, 25 and 35 mm depth in the phantom upstream the beam direction Another required parameter for determining the conversion coefficients from was the mean energy of the x-ray spectrum. The spectroscopy of x-ray beams was done with a CdTe semiconductor detector that was calibrated with 133 Ba, 241 Am and 57 Co radiation sources. Measurements of the x-ray spectra were carried out for all RQR and RQA IEC qualities. Corrections due to the detector intrinsic efficiency, total energy absorption, escape fraction of the characteristic x-rays, Compton effect and attenuation in the detector were done aiming an the accurate determination of the mean energy. Measured x-ray spectra were corrected with the stripping method by using these response functions. The typical combined standard uncertainties of conversion coefficients and

  10. Smart x-ray beam position monitor system for the Advanced Photon Source

    International Nuclear Information System (INIS)

    Shu, D.; Kuzay, T.

    1996-01-01

    In third-generation synchrotron radiation sources, such as the Advanced Photon Source (APS), the sensitivity and reliability requirements for the x-ray beam position monitors (XBPMs) are much higher than for earlier systems. Noise and contamination signals caused by radiation emitted from the bending magnet become a major problem. The regular XBPM calibration process can only provide signal correction for one set of conditions for the insertion devices (ID). During normal operation, parameters affecting the ID-emitted beam, such as the gap of the ID magnets and the beam current, are the variables. A new smart x-ray beam position monitor system (SBPM) has been conceived and designed for the APS. It has a built in self-learning structure with EEPROM memory that is large enough to open-quote open-quote remember close-quote close-quote a complete set of calibration data covering all the possible operating conditions. During the self-learning mode, the monitor system initializes a series of automatic scan motions with information for different ID setups and records them into the database array. During normal operation, the SBPM corrects the normalized output according to the ID setup information and the calibration database. So that, with this novel system, the SBPM is always calibrating itself with the changing ID set up conditions. copyright 1996 American Institute of Physics

  11. Investigation of the applicability of a special parallel-plate ionization chamber for x-ray beam dosimetry

    International Nuclear Information System (INIS)

    Perini, Ana P.; Neves, Lucio P.; Caldas, Linda V.E.

    2014-01-01

    Diagnostic x-rays are the greatest source of exposition to ionizing radiation of the population worldwide. In order to obtain accurate and lower-cost dosimeters for quality control assurance of medical x-ray facilities, a special ionization chamber was designed at the Calibration Laboratory of the IPEN, for dosimetry in diagnostic radiology beams. For the chamber characterization some tests were undertaken. Monte Carlo simulations were proposed to evaluate the distribution of the deposited energy in the sensitive volume of the ionization chamber and the collecting electrode effect on the chamber response. According to the obtained results, this special ionization chamber presents potential use for dosimetry of conventional diagnostic radiology beams. - Highlights: • An ionization chamber with a novel design was characterized for x-ray beam dosimetry. • This ionization chamber was evaluated in diagnostic radiology qualities. • The characterization tests results were within the recommended limits. • Monte Carlo simulations were employed to evaluate the design of the dosimeter. • The developed prototype is a good alternative for calibration laboratories and clinics

  12. Soft X-ray generation in gases by means of a pulsed electron beam produced in a high-voltage barier discharge

    NARCIS (Netherlands)

    Azarov, A.V.; Peters, P.J.M.; Boller, Klaus J.

    2007-01-01

    A large area pulsed electron beam is produced by a high-voltage barrier discharge. We compare the properties of the x-rays generated by stopping this beam of electrons in a thin metal foil with those generated by stopping the electrons directly in various gases. The generation of x-rays was

  13. Performance and beam characteristics of the PANTAK THERAPAX HF225 X-ray therapy machine

    Energy Technology Data Exchange (ETDEWEB)

    Yiannakkaras, C; Papadopoulos, N; Christodoulides, G [Department of Medical Physics, Nicosia General Hospital, 1450 Nicosia (Cyprus)

    1999-12-31

    The performance and beam characteristics of the new PANTAK THERAPAX HF225 X-ray therapy machine have been measured, evaluated and discussed. Eight beam qualities within the working range of generating potentials between 50 and 225 kVp are used in our department. These beam qualities have been investigated in order to provide a data base specific to our machine. Beam Quality, Central Axis Depth Dose, Output, Relative Field Uniformity and Timer Error were investigated. (authors) 11 refs., 4 figs., 9 tabs.

  14. Development and applications of grazing exit micro X-ray fluorescence instrument using a polycapillary X-ray lens

    International Nuclear Information System (INIS)

    Emoto, T.; Sato, Y.; Konishi, Y.; Ding, X.; Tsuji, K.

    2004-01-01

    A polycapillary X-ray lens is an effective optics to obtain a μm-size X-ray beam for micro-X-ray fluorescence spectrometry (μ-XRF). We developed a μ-XRF instrument using a polycapillary X-ray lens, which also enabled us to perform Grazing Exit μ-XRF (GE-μ-XRF). The evaluated diameter of the primary X-ray beam was 48 μm at the focal distance of the X-ray lens. Use of this instrument enabled two-dimensional mapping of the elemental distributions during growth of the plant 'Quinoa'. The results of the mapping revealed elemental transition during growth. In addition, a small region of thin film was analyzed by GE-μ-XRF. We expect that GE-μ-XRF will become an effective method of estimating the film thickness of a small region

  15. X-ray tubes

    International Nuclear Information System (INIS)

    Young, R.W.

    1979-01-01

    A form of x-ray tube is described which provides satisfactory focussing of the electron beam when the beam extends for several feet from gun to target. Such a tube can be used for computerised tomographic scanning. (UK)

  16. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... standards used by radiology professionals. Modern x-ray systems have very controlled x-ray beams and dose control methods to minimize stray (scatter) radiation. This ensures that those parts of a patient's body not being imaged receive minimal radiation exposure. ...

  17. Frequency filter of seed x-ray by use of x-ray laser medium. Toward the generation of the temporally coherent x-ray laser

    International Nuclear Information System (INIS)

    Hasegawa, Noboru; Kawachi, Tetsuya; Kishimoto, Maki; Sukegawa, Kouta; Tanaka, Momoko; Ochi, Yoshihiro; Nishikino, Masaharu; Nagashima, Keisuke; Kato, Yoshiaki; Renzhong, Tai

    2009-01-01

    We evaluate the characteristics of a higher-order harmonics light as a seed X-ray amplified through a laser-produced X-ray amplifier. The narrow spectral bandwidth of the X-ray amplifier works as the frequency filter of the seed X-ray, resulting in that only the temporally coherent X-ray is amplified. Experimental investigation using the 29th-order harmonic light of the Ti:sapphire laser at a wavelength of 26.9 nm together with a neon-like manganese X-ray laser medium shows evident spectral narrowing of the seed X-ray and amplification without serious diffraction effects on the propagation of the amplified X-ray beam. This implies that the present combination is potential to realize temporally coherent X-ray lasers, with an expected duration of approximately 400 fs. (author)

  18. Application of focused-beam flat-sample method to synchrotron powder X-ray diffraction with anomalous scattering effect

    International Nuclear Information System (INIS)

    Tanaka, M; Katsuya, Y; Matsushita, Y

    2013-01-01

    The focused-beam flat-sample method (FFM), which is a method for high-resolution and rapid synchrotron X-ray powder diffraction measurements by combination of beam focusing optics, a flat shape sample and an area detector, was applied for diffraction experiments with anomalous scattering effect. The advantages of FFM for anomalous diffraction were absorption correction without approximation, rapid data collection by an area detector and good signal-to-noise ratio data by focusing optics. In the X-ray diffraction experiments of CoFe 2 O 4 and Fe 3 O 4 (By FFM) using X-rays near the Fe K absorption edge, the anomalous scattering effect between Fe/Co or Fe 2+ /Fe 3+ can be clearly detected, due to the change of diffraction intensity. The change of observed diffraction intensity as the incident X-ray energy was consistent with the calculation. The FFM is expected to be a method for anomalous powder diffraction.

  19. Excitation-resolved cone-beam x-ray luminescence tomography.

    Science.gov (United States)

    Liu, Xin; Liao, Qimei; Wang, Hongkai; Yan, Zhuangzhi

    2015-07-01

    Cone-beam x-ray luminescence computed tomography (CB-XLCT), as an emerging imaging technique, plays an important role in in vivo small animal imaging studies. However, CB-XLCT suffers from low-spatial resolution due to the ill-posed nature of reconstruction. We improve the imaging performance of CB-XLCT by using a multiband excitation-resolved imaging scheme combined with principal component analysis. To evaluate the performance of the proposed method, the physical phantom experiment is performed with a custom-made XLCT/XCT imaging system. The experimental results validate the feasibility of the method, where two adjacent nanophosphors (with an edge-to-edge distance of 2.4 mm) can be located.

  20. Kharkov X-ray Generator Based On Compton Scattering

    International Nuclear Information System (INIS)

    Shcherbakov, A.; Zelinsky, A.; Mytsykov, A.; Gladkikh, P.; Karnaukhov, I.; Lapshin, V.; Telegin, Y.; Androsov, V.; Bulyak, E.; Botman, J.I.M.; Tatchyn, R.; Lebedev, A.

    2004-01-01

    Nowadays X-ray sources based on storage rings with low beam energy and Compton scattering of intense laser beams are under development in several laboratories. An international cooperative project of an advanced X-ray source of this type at the Kharkov Institute of Physics and Technology (KIPT) is described. The status of the project is reviewed. The design lattice of the storage ring and calculated X-ray beam parameters are presented. The results of numerical simulation carried out for proposed facility show a peak spectral X-ray intensity of about 1014 can be produced

  1. X-ray facility for the ground calibration of the X-ray monitor JEM-X on board INTEGRAL

    DEFF Research Database (Denmark)

    Loffredo, G.; Pelliciari, C.; Frontera, F.

    2003-01-01

    We describe the X-ray facility developed for the calibration of the X-ray monitor JEM-X on board the INTEGRAL satellite. The apparatus allowed the scanning of the detector geometric area with a pencil beam of desired energy over the major part of the passband of the instrument. The monochromatic...

  2. Spot size characterization of focused non-Gaussian X-ray laser beams.

    Science.gov (United States)

    Chalupský, J; Krzywinski, J; Juha, L; Hájková, V; Cihelka, J; Burian, T; Vysín, L; Gaudin, J; Gleeson, A; Jurek, M; Khorsand, A R; Klinger, D; Wabnitz, H; Sobierajski, R; Störmer, M; Tiedtke, K; Toleikis, S

    2010-12-20

    We present a new technique for the characterization of non-Gaussian laser beams which cannot be described by an analytical formula. As a generalization of the beam spot area we apply and refine the definition of so called effective area (A(eff)) [1] in order to avoid using the full-width at half maximum (FWHM) parameter which is inappropriate for non-Gaussian beams. Furthermore, we demonstrate a practical utilization of our technique for a femtosecond soft X-ray free-electron laser. The ablative imprints in poly(methyl methacrylate) - PMMA and amorphous carbon (a-C) are used to characterize the spatial beam profile and to determine the effective area. Two procedures of the effective area determination are presented in this work. An F-scan method, newly developed in this paper, appears to be a good candidate for the spatial beam diagnostics applicable to lasers of various kinds.

  3. SU-F-I-75: Half-Value Layer Thicknesses and Homogeneity Coefficients for Fluoroscopic X-Ray Beam Spectra Incorporating Spectral Filtration

    Energy Technology Data Exchange (ETDEWEB)

    Wunderle, K [Cleveland Clinic Foundation, Cleveland, OH (United States); Wayne State University School of Medicine, Detroit, MI (United States); Godley, A; Shen, Z; Dong, F [Cleveland Clinic Foundation, Cleveland, OH (United States); Rakowski, J [Wayne State University School of Medicine, Detroit, MI (United States)

    2016-06-15

    Purpose: The purpose of this investigation is to quantify various first half-value-layers (HVLs), second HVLs and homogeneity coefficients (HCs) for a state-of-the-art fluoroscope utilizing spectral (copper) filtration. Methods: A Radcal (Monrovia, Ca) AccuPro dosimeter with a 10×6-6 calibrated ionization chamber was used to measure air kerma for radiographic x-ray exposures made on a Siemens (Erlangen, Germany) Artis ZeeGo fluoroscope operated in the service mode. The ionization chamber was centered in the x-ray beam at 72 cm from the focal spot with a source-to-image-distance of 120 cm. The collimators were introduced to limit the x-ray field to approximately 5 cm × 5 cm at the ionization chamber plane. Type-1100 aluminum filters, in 0.5 mm increments, were used to determine the HVL. Two HVL calculation methods were used, log-linear interpolation and Lambert-W interpolation as described by Mathieu [Med Phys, 38(8), 4546 (2011)]. Multiple measurements were made at 60, 80, 100, 120 kVp at spectral filtration thicknesses of 0, 0.1, 0.3, 0.6 and 0.9 mm. Results: First HVL, second HVL, and HCs are presented for the fluoroscopic x-ray beam spectra indicated above, with nearly identical results from the two interpolation methods. Accuracy of the set kVp was also determined and deviated less than 2%. First HVLs for fluoroscopic x-ray beam spectra without spectral filtration determined in our study were 7%–16% greater than previously published data by Fetterly et al. [Med Phys, 28, 205 (2001)]. However, the FDA minimum HVL requirements changed since that publication, requiring larger HVLs as of 2006. Additionally, x-ray tube and generator architecture have substantially changed over the last 15 years providing different beam spectra. Conclusion: X-ray beam quality characteristics for state-of-the-art fluoroscopes with spectral filtration have not been published. This study provides reference data which will be useful for defining beam qualities encountered on

  4. Design studies for ITER x-ray diagnostics

    International Nuclear Information System (INIS)

    Hill, K.W.; Bitter, M.; von Goeler, S.; Hsuan, H.

    1995-01-01

    Concepts for adapting conventional tokamak x-ray diagnostics to the harsh radiation environment of ITER include use of grazing-incidence (GI) x-ray mirrors or man-made Bragg multilayer (ML) elements to remove the x-ray beam from the neutron beam, or use of bundles of glass-capillary x-ray ''light pipes'' embedded in radiation shields to reduce the neutron/gamma-ray fluxes onto the detectors while maintaining usable x-ray throughput. The x-ray optical element with the broadest bandwidth and highest throughput, the GI mirror, can provide adequate lateral deflection (10 cm for a deflected-path length of 8 m) at x-ray energies up to 12, 22, or 30 keV for one, two, or three deflections, respectively. This element can be used with the broad band, high intensity x-ray imaging system (XIS), the pulseheight analysis (PHA) survey spectrometer, or the high resolution Johann x-ray crystal spectrometer (XCS), which is used for ion-temperature measurement. The ML mirrors can isolate the detector from the neutron beam with a single deflection for energies up to 50 keV, but have much narrower bandwidth and lower x-ray power throughput than do the GI mirrors; they are unsuitable for use with the XIS or PHA, but they could be used with the XCS; in particular, these deflectors could be used between ITER and the biological shield to avoid direct plasma neutron streaming through the biological shield. Graded-d ML mirrors have good reflectivity from 20 to 70 keV, but still at grazing angles (<3 mrad). The efficiency at 70 keV for double reflection (10 percent), as required for adequate separation of the x-ray and neutron beams, is high enough for PHA requirements, but not for the XIS. Further optimization may be possible

  5. Development and applications of grazing exit micro X-ray fluorescence instrument using a polycapillary X-ray lens

    Energy Technology Data Exchange (ETDEWEB)

    Emoto, T.; Sato, Y.; Konishi, Y.; Ding, X.; Tsuji, K. E-mail: tsuji@a-chem.eng.osaka-cu.ac.jp

    2004-08-31

    A polycapillary X-ray lens is an effective optics to obtain a {mu}m-size X-ray beam for micro-X-ray fluorescence spectrometry ({mu}-XRF). We developed a {mu}-XRF instrument using a polycapillary X-ray lens, which also enabled us to perform Grazing Exit {mu}-XRF (GE-{mu}-XRF). The evaluated diameter of the primary X-ray beam was 48 {mu}m at the focal distance of the X-ray lens. Use of this instrument enabled two-dimensional mapping of the elemental distributions during growth of the plant 'Quinoa'. The results of the mapping revealed elemental transition during growth. In addition, a small region of thin film was analyzed by GE-{mu}-XRF. We expect that GE-{mu}-XRF will become an effective method of estimating the film thickness of a small region.

  6. X-ray spectra from the Cornell Electron-Beam Ion Source (CEBIS I)

    International Nuclear Information System (INIS)

    Johnson, B.M.; Jones, K.W.; Kostroun, V.O.; Ghanbari, E.; Janson, S.W.

    1985-01-01

    Radiation emitted from the Cornell electron beam ion source (CEBIS I) has been surveyed with a Si(Li) x-ray detector. These spectra can be used to estimate backgrounds from electron bremsstrahlung and to evaluate the feasibility of atomic physics experiments using the CEBIS I source in this configuration. 1 ref., 2 figs

  7. Evaluation of secondary electron filter for removing contaminant electrons from high-energy 6 MV x-ray beam

    International Nuclear Information System (INIS)

    Kumagai, Kozo

    1988-01-01

    When using high energy X-rays, the dose increases at the skin surface and build-up region of beam contamination of secondary electrons coming out from the inner surface of the lineac head. At our radiotherapy department, many cases of external otitis from severe skin reactions, particularly resulting from whole brain irradiation of primary and metastatic brain tumors with a 6 MV X-ray lineac, have been encountered. An investigation was made of the physical aspects of a 6 MV X-ray beam using three electron filters, lead lucite, lead glass and lucite to remove secondary electrons. Transparent materials for filters should be preferable for locating the light field. The following results were obtained: 1) For removing secondary electrons, a lead lucite filter was found best. 2) The lead lucite filter proved most effective for removing secondary electrons from the area of treatment. It reduced the dose of irradiation to the skin surface and build-up region, and furthermore improved the depth dose relative to that without filters. 3) From a clinical standpoint, skin reactions such as external otitis remarkably decreased using a lead lucite filter. 4) It thus appears necessary to use a high energy X-ray with newly designed filters to reduce beam contamination of secondary electrons. (author)

  8. Analysis of a Novel Diffractive Scanning-Wire Beam Position Monitor (BPM) for Discriminative Profiling of Electron Vs. X Ray Beams

    International Nuclear Information System (INIS)

    Tatchyn, R.

    2011-01-01

    Recent numerical studies of Free Electron Lasers (FELs) operating in the Self Amplified Spontaneous Emission (SASE) regime indicate a large sensitivity of the gain to the degree of transverse overlap (and associated phase coherence) between the electron and photon beams traveling down the insertion device. Simulations of actual systems imply that accurate detection and correction for this relative loss of overlap, rather than correction for the absolute departure of the electron beam from a fixed axis, is the preferred function of an FEL amplifier's Beam Position Monitor (BPM) and corrector systems. In this note we propose a novel diffractive BPM with the capability of simultaneously detecting and resolving the absolute (and relative) transverse positions and profiles of electron and x-ray beams co-propagating through an undulator. We derive the equations governing the performance of the BPM and examine its predicted performance for the SLAC Linac Coherent Light Source (LCLS), viz., for profiling multi-GeV electron bunches co-propagating with one-to-several-hundred keV x-ray beams. Selected research and development (r and d) tasks for fabricating and testing the proposed BPM are discussed.

  9. Bone X-Ray (Radiography)

    Medline Plus

    Full Text Available ... have very controlled x-ray beams and dose control methods to minimize stray (scatter) radiation. This ensures that those parts of a patient's body not being imaged receive minimal radiation exposure. top of page What are the limitations of Bone X-ray (Radiography)? ...

  10. Control console for the X-ray room

    International Nuclear Information System (INIS)

    Garcia H, J.M.; Aguilar B, M.A.; Torres B, M.A.

    1998-01-01

    It is presented the design and construction of Control console for the X-ray room of Metrology Center for ionizing radiations at National Institute of Nuclear Research (ININ). This system controls the positioning of 6 different filters for an X-ray beam. Also it controls a shutter which blockades the beam during periods established by user, these periods can be fixed from hours until tenth of second. The shutter opening periods, as well as the X-ray beam filter are establish and monitoring from a Personal computer outside of room. (Author)

  11. X-ray radiotherapy

    International Nuclear Information System (INIS)

    Tronc, D.

    1995-01-01

    Full text: The most common form of radio therapy is X-ray therapy, where a beam of photons or their parent electrons break down hydrogen bonds within the body's cells and remove certain DNA information necessary for cell multiplication. This process can eradicate malignant cells leading to complete recovery, to the remission of some cancers, or at least to a degree of pain relief. The radiotherapy instrument is usually an electron linac, and the electrons are used either directly in 'electrotherapy' for some 10% of patients, or the electrons bombard a conversion target creating a broad beam of high energy photons or 'penetration X-rays'. The simplest machine consists of several accelerating sections at around 3 GHz, accelerating electrons to 6 MeV; a cooled tungsten target is used to produce a 4 Gray/min X-ray field which can be collimated into a rectangular shape at the patient position. This tiny linac is mounted inside a rotating isocentric gantry above the patient who must remain perfectly still. Several convergent beams can also be used to increase the delivered dose. More sophisticated accelerators operate at up to 18 MeV to increase penetration depths and decrease skin exposure. Alternatively, electrotherapy can be used with different energies for lower and variable penetration depths - approximately 0.5 cm per MeV. In this way surface tissue may be treated without affecting deeper and more critical anatomical regions. This type of linac, 1 to 2 metres long, is mounted parallel to the patient with a bending magnet to direct the beam to the radiotherapy system, which includes the target, thick movable collimator jaws, a beam field equalizer, dose rate and optical field simulation and energy controls. There are over 2000 acceleratorbased X-ray treatment units worldwide. Western countries have up to two units per million population, whereas in developing countries such as Bangladesh, the density is only one per 100 million. Several

  12. Characteristics of kilovoltage x-ray beams used for cone-beam computed tomography in radiation therapy

    International Nuclear Information System (INIS)

    Ding, George X; Duggan, Dennis M; Coffey, Charles W

    2007-01-01

    The purpose of this investigation is to characterize the beams produced by a kilovoltage (kV) imager integrated into a linear accelerator (Varian on-board imager integrated into the Trilogy accelerator) for acquiring high resolution volumetric cone-beam computed tomography (CBCT) images of the patient on the treatment table. The x-ray tube is capable of generating photon spectra with kVp values between 40 and 125 kV. The Monte Carlo simulations were used to study the characteristics of kV beams and the properties of imaged target scatters. The Monte Carlo results were benchmarked against measurements, and excellent agreements were obtained. We also studied the effect of including the electron impact ionization (EII), and the simulation showed that the characteristic radiation is increased significantly in the energy spectra when EII is included. Although only slight beam hardening is observed in the spectra of all photons after passing through the phantom target, there is a significant difference in the spectra and angular distributions between scattered and primary photons. The results also show that the photon fluence distributions are significantly altered by adding bow tie filters. The results indicate that a combination of large cone-beam field size and large imaged target significantly increases scatter-to-primary ratios for photons that reach the detector panel. For phantoms 10 cm, 20 cm and 30 cm thick of water placed at the isocentre, the scatter-to-primary ratios are 0.94, 3.0 and 7.6 respectively for an open 125 kVp CBCT beam. The Monte Carlo simulations show that the increase of the scatter is proportional to the increase of the imaged volume, and this also applies to scatter-to-primary ratios. This study shows both the magnitude and the characteristics of scattered x-rays. The knowledge obtained from this investigation may be useful in the future design of the image detector to improve the image quality

  13. Multilayer X-ray mirrors for formation of sub-nanometer wavelength range beams

    International Nuclear Information System (INIS)

    Akhsakhalyan, A.A.; Akhsakhalyan, A.D.; Klyuenkov, E.B.; Murav'ev, V.A.; Salashchenko, N.N.; Kharitonov, A.I.

    2005-01-01

    Paper reviews the efforts undertaken in the RF Academy of Sciences IPM within recent 5 years to design multilayer mirror systems to produce X-ray wavelength subnanometer range beams. Paper describes a process to fabricate the mentioned systems covering the procedures to obtain supersmooth surfaces of the specified shape, to deposit gradient multilayer structures on the mentioned surfaces and describes the rules to calculate the optimal parameters of mirrors. Paper presents characteristics of mirror system two types: a mirror in the shape of a parabolic cylinder to collimate radiation in the DRON-4, DRON-6 production-type X-ray diffractometers and in the shape of a quadraelliptic reflector - a new wide-aperture four-corner focusing system [ru

  14. Electron beam production and characterization for the PLEIADES Thomson X-ray source

    International Nuclear Information System (INIS)

    Brown, W.J.; Hartemann, F.V.; Tremaine, A.M.; Springer, P.T.; Le Sage, G.P.; Barty, C.P.J.; Crane, J.K.; Cross, R.R.; Fittinghoff, D.N.; Slaughter, D.R.; Rosenzweig, J.B.; Anderson, S.; Gibson, D.J.

    2002-01-01

    We report on the performance of an S-band RF photocathode electron gun and accelerator for operation with the PLEIADES Thomson x-ray source at LLNL. Simulations of beam production, transport, and focus are presented. It is shown that a 1 ps, 500 pC electron bunch with a normalized emittance of less than 5 πmm-mrad can be delivered to the interaction point. Initial electron measurements are presented. Calculations of expected x-ray flux are also performed, demonstrating an expected peak spectral brightness of 1020 photons/s/mm2/mrad2/0.1% bandwidth. Effects of RF phase jitter are also presented, and planned phase measurements and control methods are discussed

  15. Experimental investigation for determination of optimal X-ray beam tube voltages in a newly developed digital breast tomosynthesis system

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hye-Suk, E-mail: radiosugar@yonsei.ac.kr [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of); Kim, Ye-Seul, E-mail: radiohesugar@gmail.com [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of); Choi, Young-Wook, E-mail: ywchoi@keri.re.kr [Korea Electrotechnology Research Institute (KERI), Ansan, Geongki 426-170 (Korea, Republic of); Choi, JaeGu, E-mail: jgchoi88@paran.com [Korea Electrotechnology Research Institute (KERI), Ansan, Geongki 426-170 (Korea, Republic of); Rhee, Yong-Chun, E-mail: ycrhee@yonsei.ac.kr [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of); Kim, Hee-Joung, E-mail: hjk1@yonsei.ac.kr [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of)

    2014-11-01

    Our purpose was to investigate optimal tube voltages (kVp) for a newly developed digital breast tomosynthesis (DBT) process and to determine tube current–exposure time products (mA s) for the average glandular dose (AGD), which is similar to that of the two views in conventional mammography (CM). In addition, the optimal acquisition parameters for this system were compared with those of CM. The analysis was based on the contrast-to-noise ratio (CNR) from the simulated micro-calcifications on homogeneous phantoms, and the figure of merit (FOM) was retrieved from the CNR and AGD at X-ray tube voltages ranging from 24 to 40 kVp at intervals of 2 kV. The optimal kVp increased more than 2 kV with increasing glandularity for thicker (≥50 mm) breast phantoms. The optimal kVp for DBT was found to be 4–7 kV higher than that calculated for CM with breast phantoms thicker than 50 mm. This is likely due to the greater effect of noise and dose reduction by kVp increment when using the lower dose per projection in DBT. It is important to determine optimum acquisition conditions for a maximally effective DBT system. The results of our study provide useful information to further improve DBT for high quality imaging.

  16. Present status of research and development on X-ray microprobe

    International Nuclear Information System (INIS)

    Koike, Masaki; Suzuki, I.H.

    1991-01-01

    X-ray beam micro-analysis has advanced rapidly in these years in conjunction with the development of powerful X-ray sources. Among a variety of methods being attempted, the method using a collimated narrow beam has been important because of high brightness, and of usability in both regions of soft and hard X-rays. In the soft X-ray region, the focused beam is formed by a fresnel zone plate or a Schwaltzschild mirror assembly, and can be used for scanning transmission microscope or scanning photoelectron microscope. In the hard X-ray region, the beam is formed by grazing incidence mirrors, and can be used for X-ray fluorescence micro-analysis for obtaining elemental mapping. In this report, the recent progress on the soft X-ray scanning microscopy and the X-ray microprobe has been surveyed, together with the improvement on the related optical elements. (author) 84 refs

  17. Time resolved, 2-D hard X-ray imaging of relativistic electron-beam target interactions on ETA-II

    International Nuclear Information System (INIS)

    Crist, C.E.; Sampayan, S.; Westenskow, G.; Caporaso, G.; Houck, T.; Weir, J.; Trimble, D.; Krogh, M.

    1998-01-01

    Advanced radiographic applications require a constant source size less than 1 mm. To study the time history of a relativistic electron beam as it interacts with a bremsstrahlung converter, one of the diagnostics they use is a multi-frame time-resolved hard x-ray camera. They are performing experiments on the ETA-II accelerator at Lawrence Livermore National Laboratory to investigate details of the electron beam/converter interactions. The camera they are using contains 6 time-resolved images, each image is a 5 ns frame. By starting each successive frame 10 ns after the previous frame, they create a 6-frame movie from the hard x-rays produced from the interaction of the 50-ns electron beam pulse

  18. Flat Field Anomalies in an X-Ray CCD Camera Measured Using a Manson X-Ray Source

    International Nuclear Information System (INIS)

    Michael Haugh

    2008-01-01

    The Static X-ray Imager (SXI) is a diagnostic used at the National Ignition Facility (NIF) to measure the position of the X-rays produced by lasers hitting a gold foil target. It determines how accurately NIF can point the laser beams and is critical to proper NIF operation. Imagers are located at the top and the bottom of the NIF target chamber. The CCD chip is an X-ray sensitive silicon sensor, with a large format array (2k x 2k), 24 (micro)m square pixels, and 15 (micro)m thick. A multi-anode Manson X-ray source, operating up to 10kV and 2mA, was used to characterize and calibrate the imagers. The output beam is heavily filtered to narrow the spectral beam width, giving a typical resolution E/ΔE ∼ 12. The X-ray beam intensity was measured using an absolute photodiode that has accuracy better than 1% up to the Si K edge and better than 5% at higher energies. The X-ray beam provides full CCD illumination and is flat, within ±1.5% maximum to minimum. The spectral efficiency was measured at 10 energy bands ranging from 930 eV to 8470 eV. The efficiency pattern follows the properties of Si. The maximum quantum efficiency is 0.71. We observed an energy dependent pixel sensitivity variation that showed continuous change over a large portion of the CCD. The maximum sensitivity variation was >8% at 8470 eV. The geometric pattern did not change at lower energies, but the maximum contrast decreased and was less than the measurement uncertainty below 4 keV. We were also able to observe debris on the CCD chip. The debris showed maximum contrast at the lowest energy used, 930 eV, and disappeared by 4 keV. The Manson source is a powerful tool for characterizing the imaging errors of an X-ray CCD imager. These errors are quite different from those found in a visible CCD imager

  19. Confocal total reflection X-ray fluorescence technology based on an elliptical monocapillary and a parallel polycapillary X-ray optics.

    Science.gov (United States)

    Zhu, Yu; Wang, Yabing; Sun, Tianxi; Sun, Xuepeng; Zhang, Xiaoyun; Liu, Zhiguo; Li, Yufei; Zhang, Fengshou

    2018-07-01

    A total reflection X-ray fluorescence (TXRF) spectrometer based on an elliptical monocapillary X-ray lens (MXRL) and a parallel polycapillary X-ray lens (PPXRL) was designed. This TXRF instrument has micro focal spot, low divergence and high intensity of incident X-ray beam. The diameter of the focal spot of MXRL was 16.5 µm, and the divergence of the incident X-ray beam was 3.4 mrad. We applied this TXRF instrument to the micro analysis of a single-layer film containing Ni deposited on a Si substrate by metal vapor vacuum arc ion source. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Synchrotron X-ray micro-beam studies of ancient Egyptian make-up

    International Nuclear Information System (INIS)

    Martinetto, P.; Anne, M.; Dooryhee, E.; Drakopoulos, M.; Dubus, M.; Salomon, J.; Simionovici, A.; Walter, Ph.

    2001-01-01

    Vases full of make-up are most often present in the burial furniture of Egyptian tombs dated from the pharaonic period. The powdered cosmetics made of isolated grains are analysed to identify their trace element signature. From this signature we identify the provenance of the mineral ingredients in the make-up and we observe different impurities in products, which have been demonstrated as synthetic substances by previous works. Focused X-ray micro-beam (2x5 μm 2 ) is successively tuned at 11 keV, below the L III absorption edge of Pb, and 31.8 keV for global characterisation of the metal impurities. The fluorescence signal integrated over each single grain is detected against the X-ray micro-diffraction pattern collected in transmission with a bi-dimensional detector. Furthermore, for galena grains rich in Zn, the XANES signal at the K-absorption edge of Zn shows its immediate nearest-neighbour environment

  1. Synchrotron X-ray micro-beam studies of ancient Egyptian make-up

    Energy Technology Data Exchange (ETDEWEB)

    Martinetto, P; Anne, M; Dooryhee, E; Drakopoulos, M; Dubus, M; Salomon, J; Simionovici, A; Walter, Ph

    2001-07-01

    Vases full of make-up are most often present in the burial furniture of Egyptian tombs dated from the pharaonic period. The powdered cosmetics made of isolated grains are analysed to identify their trace element signature. From this signature we identify the provenance of the mineral ingredients in the make-up and we observe different impurities in products, which have been demonstrated as synthetic substances by previous works. Focused X-ray micro-beam (2x5 {mu}m{sup 2}) is successively tuned at 11 keV, below the L{sub III} absorption edge of Pb, and 31.8 keV for global characterisation of the metal impurities. The fluorescence signal integrated over each single grain is detected against the X-ray micro-diffraction pattern collected in transmission with a bi-dimensional detector. Furthermore, for galena grains rich in Zn, the XANES signal at the K-absorption edge of Zn shows its immediate nearest-neighbour environment.

  2. Installation And Test Of Electron Beam Generation System To Produce Far-Infrared Radiation And X-Ray Pulses

    International Nuclear Information System (INIS)

    Wichaisirimongkol, Pathom; Jinamoon, Witoon; Khangrang, Nopadon; Kusoljariyakul, Keerati; Rhodes, Michael W.; Rimjaem, Sakhorn; Saisut, Jatuporn; Chitrlada, Thongbai; Vilaithong, Thiraphat; Wiedemann, Helmut

    2005-10-01

    SURIYA project at the Fast Neutron Research Facility, Chiang Mai University, aims to establish a facility to generate femtosecond electron beams. This electron beam can be used to generate high intensity far-infrared radiation and ultra-short X-ray pulses. The main components of the system are a 3 MeV RF electron gun with a thermionic cathode, an a-magnet as a bunch compressor, and post acceleration 15-20 MeV by a linear accelerator (linac). Between the main components, there are focusing quadrupole magnets and steering magnets to maintain the electron beam within a high vacuum tube. At the end of the beam transport line, a dipole magnet has been installed to function as a beam dump and an energy spectrometer. After the installation and testing of individual major components were completed, we have been investigating the generation of the electron beam, intense far- infrared radiation and ultra short X-ray pulses

  3. Collimating device for x-rays

    International Nuclear Information System (INIS)

    Schroeder, C.H.

    1978-01-01

    A position indicating device which attaches to an X-ray machine is provided with a collar onto which a lead lined cylinder may be threaded. The cylinder has an end plate through which a rectangular opening is formed in order to provide a rectangular X-ray beam for use in cephalometric radiography. When the cylinder is removed, a circular beam is emitted for use in intra-oral radiography

  4. Identification of human breast pathologies by X-ray elastic scattering; Identificacao de patologias mamarias atraves do espalhamento elastico de raios X

    Energy Technology Data Exchange (ETDEWEB)

    Conceicao, Andre L.C.; Antoniassi, Marcelo; Poletti, Martin E., E-mail: andre_conceicao@yahoo.com.b [Universidade de Sao Paulo (FFCLRP/USP), Ribeirao Preto, SP (Brazil). Faculdade de Filosofia, Ciencias e Letras. Dept. de Fisica e Matematica

    2011-07-01

    In this paper we determine the scattering profiles of normal, benign and malignant human breast samples in a momentum transfer range of 0.07nm{sup -1} {<=}q{<=}70.55nm{sup -1}, resulted from combining WAXS (wide angle x-ray scattering) and SAXS (small angle x-ray scattering) data. The results showed considerable differences between the scattering profiles of each tissue type. Based on this fact, some parameters, representing structural features, were extracted from these scattering profiles and submitted to a discriminant analysis. From statistical analysis, the ratio between the peak intensities at q=19.8nm{sup -1} and q=13.9nm{sup -1} and the intensity of third order axial collagen peak arose as two potentials breast tissue classifiers and, from combining them it was possible differentiate among normal, benign and malignant lesions. (author)

  5. Time-resolved x-ray line emission studies of thermal transport in multiple beam uv-irradiated targets

    International Nuclear Information System (INIS)

    Jaanimagi, P.A.; Henke, B.L.; Delettrez, J.; Richardson, M.C.

    1984-01-01

    Thermal transport in spherical targets irradiated with multiple, nanosecond duration laser beams, has been a topic of much discussion recently. Different inferences on the level of thermal flux inhibition have been drawn from plasma velocity and x-ray spectroscopic diagnostics. We present new measurements of thermal transport on spherical targets made through time-resolved x-ray spectroscopic measurements of the progress of the ablation surface through thin layers of material on the surface of the target. These measurements, made with 6 and 12 uv (351 nm) nanosecond beams from OMEGA, will be compared to previous thermal transport measurements. Transparencies of the conference presentation are given

  6. Output Beam Polarisation of X-ray Lasers with Transient Inversion

    Science.gov (United States)

    Janulewicz, K. A.; Kim, C. M.; Matouš, B.; Stiel, H.; Nishikino, M.; Hasegawa, N.; Kawachi, T.

    It is commonly accepted that X-ray lasers, as the devices based on amplified spontaneous emission (ASE), did not show any specific polarization in the output beam. The theoretical analysis within the uniform (single-mode) approximation suggested that the output radiation should show some defined polarization feature, but randomly changing from shot-to-shot. This hypothesis has been verified by experiment using traditional double-pulse scheme of transient inversion. Membrane beam-splitter was used as a polarization selector. It was found that the output radiation has a significant component of p-polarisation in each shot. To explain the effect and place it in the line with available, but scarce data, propagation and kinetic effects in the non-uniform plasma have been analysed.

  7. Comparison of the efficacy of preoperative X-ray and thermoradiotherapy used for the treatment of breast cancer

    International Nuclear Information System (INIS)

    Muravskaya, G.V.; Pantyushenko, T.A.; Fradkin, S.Z.; Zhavrid, Eh.A.; Moiseenko, V.V.

    1984-01-01

    An experience of the first randomatized clinical investigation on the usage of different variants of preoperative X-ray (with simultaneous local UHF hyperthepmia and without it) action in the case of combined treatment of patients with breast cancer has been summarized. It has been shown that conventional values of preoperative X-ray therapy (about 30-45 G.) are optimum ones. An increase of complex thermoradiotherapy efficacy in the case of considered cancer forms may be achieved at the expense of a stre gthening of preoperative X-ray action by means of dose increase up to the cancerogenic level or preoperative irradiation under the conditions of local UHF-hyperthermia

  8. Parabolic refractive X-ray lenses: a breakthrough in X-ray optics

    CERN Document Server

    Lengeler, B; Benner, B; Guenzler, T F; Kuhlmann, M; Tümmler, J; Simionovici, A S; Drakopoulos, M; Snigirev, A; Snigireva, I

    2001-01-01

    Refractive X-ray lenses, considered for a long time as unfeasible, have been realized with a rotational parabolic profile at our institute: The main features of the new lenses are: they focus in two directions and are free of spherical aberration. By varying the number of individual lenses in the stack the focal length can be chosen in a typical range from 0.5 to 2 m for photon energies between about 6 and 60 keV. The aperture of the lens is about 1 mm matching the angular divergence of undulator beams at 3d generation synchrotron radiation sources. They cope without problems with the heat load from the white beam of an undulator. Finally, they are easy to align and to operate. Refractive X-ray lenses can be used with hard X-rays in the same way as glass lenses can be used for visible light, if it is take into account that the numerical aperture is small (of the order 10 sup - sup 4). Being high-quality optical elements, the refractive X-ray lenses can be used for generating a focal spot in the mu m range wit...

  9. Dental X-ray apparatus

    International Nuclear Information System (INIS)

    Weiss, M.E.

    1980-01-01

    Intra-oral dental X-ray apparatus for panoramic radiography is described in detail. It comprises a tubular target carrier supporting at its distal end a target with an inclined forward face. Image definition is improved by positioning in the path of the X-rays a window of X-ray transmitting ceramic material, e.g. 90% oxide of Be, or Al, 7% Si0 2 . The target carrier forms a probe which can be positioned in the patient's mouth. X-rays are directed forwardly and laterally of the target to an X-ray film positioned externally. The probe is provided with a detachable sleeve having V-form arms of X-ray opaque material which serve to depress the tongue out of the radiation path and also shield the roof of the mouth and other regions of the head from the X-ray pattern. A cylindrical lead shield defines the X-ray beam angle. (author)

  10. Feasibility of X-ray analysis of multi-layer thin films at a single beam voltage

    International Nuclear Information System (INIS)

    Statham, P J

    2010-01-01

    Multi-layer analysis using electron beam excitation and X-ray spectrometry is a powerful tool for characterising layers down to 1 nm thickness and with typically 1 μm lateral resolution but does not always work. Most published applications have used WDS with many measurements at different beam voltages and considerable experience has been needed to choose lines and voltages particularly for complex multi-layer problems. A new objective mathematical approach is described which demonstrates whether X-ray analysis can obtain reliable results for an arbitrary multi-layer problem. A new algorithm embodied in 'ThinFilmID' software produces a single plot that shows feasibility of achieving results with a single EDS spectrum and suggests the optimal beam voltage. Synthesis of EDS spectra allows the precision in results to be estimated and acquisition conditions modified before wasting valuable instrument time. Thus, practicality of multi-layer thin film analysis at a single beam voltage can now be established without the extensive experimentation that was previously required by a microanalysis expert. Examples are shown where the algorithm discovers viable single-voltage conditions for applications that experts previously thought could only be addressed using measurements at more than one beam voltage.

  11. Sampling conditions of the three dimensional (3D) fan beam X ray transform

    International Nuclear Information System (INIS)

    Desbat, L.; Roux, S.; Grangeat, P.; Koenig, A.

    2003-01-01

    We give the sampling conditions of the 3 D fan beam X ray transform (3.D.F.B.X.R.T.). The motivation of this work lie in the fact that helical tomography with a single detector line is simply a sampling of this transform under the helical constraint. we give a precise description of the geometry of the essential support of Fourier transform of the 3.D.F.B.X.R.T. and we show how to derive efficient sampling. (N.C.)

  12. Compton backscattered collmated X-ray source

    Science.gov (United States)

    Ruth, Ronald D.; Huang, Zhirong

    2000-01-01

    A high-intensity, inexpensive and collimated x-ray source for applications such as x-ray lithography is disclosed. An intense pulse from a high power laser, stored in a high-finesse resonator, repetitively collides nearly head-on with and Compton backscatters off a bunched electron beam, having relatively low energy and circulating in a compact storage ring. Both the laser and the electron beams are tightly focused and matched at the interaction region inside the optical resonator. The laser-electron interaction not only gives rise to x-rays at the desired wavelength, but also cools and stabilizes the electrons against intrabeam scattering and Coulomb repulsion with each other in the storage ring. This cooling provides a compact, intense bunch of electrons suitable for many applications. In particular, a sufficient amount of x-rays can be generated by this device to make it an excellent and flexible Compton backscattered x-ray (CBX) source for high throughput x-ray lithography and many other applications.

  13. Compton backscattered collimated x-ray source

    Science.gov (United States)

    Ruth, R.D.; Huang, Z.

    1998-10-20

    A high-intensity, inexpensive and collimated x-ray source is disclosed for applications such as x-ray lithography is disclosed. An intense pulse from a high power laser, stored in a high-finesse resonator, repetitively collides nearly head-on with and Compton backscatters off a bunched electron beam, having relatively low energy and circulating in a compact storage ring. Both the laser and the electron beams are tightly focused and matched at the interaction region inside the optical resonator. The laser-electron interaction not only gives rise to x-rays at the desired wavelength, but also cools and stabilizes the electrons against intrabeam scattering and Coulomb repulsion with each other in the storage ring. This cooling provides a compact, intense bunch of electrons suitable for many applications. In particular, a sufficient amount of x-rays can be generated by this device to make it an excellent and flexible Compton backscattered x-ray (CBX) source for high throughput x-ray lithography and many other applications. 4 figs.

  14. Correlation analysis between expression of PCNA, Ki-67 and COX-2 and X-ray features in mammography in breast cancer.

    Science.gov (United States)

    Qiu, Xiaoming; Mei, Jixin; Yin, Jianjun; Wang, Hong; Wang, Jinqi; Xie, Ming

    2017-09-01

    This study investigated expression of proliferating cell nuclear antigen (PCNA), proliferation-associated nuclear antigen (Ki-67) and cyclooxygenase-2 (COX-2) in tissues of breast invasive ductal carcinoma, and analyzed the correlations between these indexes and X-ray features in mammography. A total of 90 patients who were admitted to Huangshi Central Hospital and diagnosed as breast invasive ductal carcinoma from January 2014 to January 2016 were selected. The expression of PCNA, Ki-67 and COX-2 in cancer tissues and cancer-adjacent normal tissues of patients were detected by immunohistochemical staining, and X-ray features in mammography of patients were observed. By using Spearman correlation analysis, the correlations between expression of PCNA, Ki-67 and COX-2 and X-ray features in mammography in breast cancer were investigated. As a result, the positive expression rates of PCNA, Ki-67 and COX-2 in cancer tissues of the patient groups were respectively 42.2, 45.6 and 51.1%, which were significantly higher than those in cancer-adjacent normal tissues of the control group (pcorrelation with age and tumor size (p>0.05). PCNA, Ki-67 and COX-2 expression in cancer tissues of the patient group had no correlation with the existence of lumps and localized density-increased shadows (p>0.05), but were associated with manifestations of architectural distortion, calcification as well as skin and nipple depression (pcorrelation analysis revealed that there was a significantly positive correlation between the expression of PCNA and COX-2 in cancer tissues of the patient group (r=0.676, pcorrelation between the expression of Ki-67 and COX-2 (r=0.724, pcorrelation with the expression of Ki-67 (p>0.05). In conclusion, PCNA, Ki-67 and COX-2 expression is of great significance in the occurrence, invasion and metastasis of breast invasive ductal carcinoma. There is a strong correlation between PCNA, Ki-67 and COX-2 expression levels and X-ray features in mammography in breast

  15. Establishing the standard X-ray beam qualities for calibration of dosimeters used in diagnostic radiology following IAEA-TRS457

    International Nuclear Information System (INIS)

    Duong Van Trieu; Ho Quang Tuan; Bui Duc Ky

    2014-01-01

    The determination of the patient dose needs to provide a reference dose for the patient that reference dose levels to assess the relative risk during X- ray diagnostic. This mission, We had established a number of standard beam qualities to perform calibrations of diagnostic dosimeters and methods of measuring patient dose in X-ray diagnostic. At radiation dosimetry room, we had establish RQR2, RQR3, RQR4, RQR5, RQR6 beam qualities based on IAEA-TRS457 documentation with homogeneity coefficient (h) for each beam quality in the range 0.7 - 0.8, and haft-value layers HVL1, HVL2 of experimental and IAEA is different about 10%. Established calibration method for diagnostic dosimeters as KAP meters, UNFORS dosimeters, and the TLD dosimeters, practical measurements of entrance surface air kerma on Shimadzu X-ray machines used phantom. (author)

  16. National Synchrotron Light Source users manual: Guide to the VUV and x-ray beam lines

    International Nuclear Information System (INIS)

    Gmuer, N.F.; White-DePace, S.M.

    1987-08-01

    The success of the National Synchrotron Light Source in the years to come will be based, in large part, on the size of the users community and the diversity of the scientific disciplines represented by these users. In order to promote this philosophy, this National Synchrotron Light Source (NSLS) Users Manual: Guide to the VUV and X-Ray Beam Lines, has been published. This manual serves a number of purposes. In an effort to attract new research, it will present to the scientific community-at-large the current and projected architecture and capabilities of the various VUV and x-ray beam lines and storage rings. We anticipate that this publication will be updated periodically in order to keep pace with the constant changes at the NSLS

  17. Experimental characterization of X-ray transverse coherence in the presence of beam transport optics

    DEFF Research Database (Denmark)

    Chubar, O.; Fluerasu, A.; Chu, Y.S.

    2013-01-01

    A simple Boron fiber based interference scheme [1] and other similar schemes are currently routinely used for X-ray coherence estimation at 3rd generation synchrotron radiation sources. If such a scheme is applied after a perfect monochromator and without any focusing / transport optics...... in the optical path, the interpretation of the measured interference pattern is relatively straightforward and can be done in terms of the basic parameters of the source [2]. However, if the interference scheme is used after some focusing optics, e.g. close to the X-ray beam waist, the visibility of fringes can...... be significantly affected by the new shape of the focused beam phase-space. At the same time, optical element imperfections still have a negative impact on the transverse coherence. In such situations, which are frequently encountered in experiments at beamlines, the quantitative interpretation of a measured...

  18. An empirical model of diagnostic x-ray attenuation under narrow-beam geometry

    International Nuclear Information System (INIS)

    Mathieu, Kelsey B.; Kappadath, S. Cheenu; White, R. Allen; Atkinson, E. Neely; Cody, Dianna D.

    2011-01-01

    Purpose: The purpose of this study was to develop and validate a mathematical model to describe narrow-beam attenuation of kilovoltage x-ray beams for the intended applications of half-value layer (HVL) and quarter-value layer (QVL) estimations, patient organ shielding, and computer modeling. Methods: An empirical model, which uses the Lambert W function and represents a generalized Lambert-Beer law, was developed. To validate this model, transmission of diagnostic energy x-ray beams was measured over a wide range of attenuator thicknesses [0.49-33.03 mm Al on a computed tomography (CT) scanner, 0.09-1.93 mm Al on two mammography systems, and 0.1-0.45 mm Cu and 0.49-14.87 mm Al using general radiography]. Exposure measurements were acquired under narrow-beam geometry using standard methods, including the appropriate ionization chamber, for each radiographic system. Nonlinear regression was used to find the best-fit curve of the proposed Lambert W model to each measured transmission versus attenuator thickness data set. In addition to validating the Lambert W model, we also assessed the performance of two-point Lambert W interpolation compared to traditional methods for estimating the HVL and QVL [i.e., semilogarithmic (exponential) and linear interpolation]. Results: The Lambert W model was validated for modeling attenuation versus attenuator thickness with respect to the data collected in this study (R 2 > 0.99). Furthermore, Lambert W interpolation was more accurate and less sensitive to the choice of interpolation points used to estimate the HVL and/or QVL than the traditional methods of semilogarithmic and linear interpolation. Conclusions: The proposed Lambert W model accurately describes attenuation of both monoenergetic radiation and (kilovoltage) polyenergetic beams (under narrow-beam geometry).

  19. An empirical model of diagnostic x-ray attenuation under narrow-beam geometry.

    Science.gov (United States)

    Mathieu, Kelsey B; Kappadath, S Cheenu; White, R Allen; Atkinson, E Neely; Cody, Dianna D

    2011-08-01

    The purpose of this study was to develop and validate a mathematical model to describe narrow-beam attenuation of kilovoltage x-ray beams for the intended applications of half-value layer (HVL) and quarter-value layer (QVL) estimations, patient organ shielding, and computer modeling. An empirical model, which uses the Lambert W function and represents a generalized Lambert-Beer law, was developed. To validate this model, transmission of diagnostic energy x-ray beams was measured over a wide range of attenuator thicknesses [0.49-33.03 mm Al on a computed tomography (CT) scanner, 0.09-1.93 mm Al on two mammography systems, and 0.1-0.45 mm Cu and 0.49-14.87 mm Al using general radiography]. Exposure measurements were acquired under narrow-beam geometry using standard methods, including the appropriate ionization chamber, for each radiographic system. Nonlinear regression was used to find the best-fit curve of the proposed Lambert W model to each measured transmission versus attenuator thickness data set. In addition to validating the Lambert W model, we also assessed the performance of two-point Lambert W interpolation compared to traditional methods for estimating the HVL and QVL [i.e., semi-logarithmic (exponential) and linear interpolation]. The Lambert W model was validated for modeling attenuation versus attenuator thickness with respect to the data collected in this study (R2 > 0.99). Furthermore, Lambert W interpolation was more accurate and less sensitive to the choice of interpolation points used to estimate the HVL and/or QVL than the traditional methods of semilogarithmic and linear interpolation. The proposed Lambert W model accurately describes attenuation of both monoenergetic radiation and (kilovoltage) polyenergetic beams (under narrow-beam geometry).

  20. High-resolution accelerator alignment using x-ray optics

    Directory of Open Access Journals (Sweden)

    Bingxin Yang

    2006-03-01

    Full Text Available We propose a novel alignment technique utilizing the x-ray beam of an undulator in conjunction with pinholes and position-sensitive detectors for positioning components of the accelerator, undulator, and beam line in an x-ray free-electron laser. Two retractable pinholes at each end of the undulator define a stable and reproducible x-ray beam axis (XBA. Targets are precisely positioned on the XBA using a pinhole camera technique. Position-sensitive detectors responding to both x-ray and electron beams enable direct transfer of the position setting from the XBA to the electron beam. This system has the potential to deliver superior alignment accuracy (1–3   μm for target pinholes in the transverse directions over a long distance (200 m or longer. It can be used to define the beam axis of the electron-beam–based alignment, enabling high reproducibility of the latter. This x-ray–based concept should complement the electron-beam–based alignment and the existing survey methods to raise the alignment accuracy of long accelerators to an unprecedented level. Further improvement of the transverse accuracy using x-ray zone plates will be discussed. We also propose a concurrent measurement scheme during accelerator operation to allow real-time feedback for transverse position correction.

  1. Ultrashort X-ray pulse science

    Energy Technology Data Exchange (ETDEWEB)

    Chin, Alan Hap [Univ. of California, Berkeley, CA (US). Dept. of Physics; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    1998-05-01

    A variety of phenomena involves atomic motion on the femtosecond time-scale. These phenomena have been studied using ultrashort optical pulses, which indirectly probe atomic positions through changes in optical properties. Because x-rays can more directly probe atomic positions, ultrashort x-ray pulses are better suited for the study of ultrafast structural dynamics. One approach towards generating ultrashort x-ray pulses is by 90° Thomson scattering between terawatt laser pulses and relativistic electrons. Using this technique, the author generated ~ 300 fs, 30 keV (0.4 Å) x-ray pulses. These x-ray pulses are absolutely synchronized with ultrashort laser pulses, allowing femtosecond optical pump/x-ray probe experiments to be performed. Using the right-angle Thomson scattering x-ray source, the author performed time-resolved x-ray diffraction studies of laser-perturbated InSb. These experiments revealed a delayed onset of lattice expansion. This delay is due to the energy relaxation from a dense electron-hole plasma to the lattice. The dense electron-hole plasma first undergoes Auger recombination, which reduces the carrier concentration while maintaining energy content. Longitudinal-optic (LO) phonon emission then couples energy to the lattice. LO phonon decay into acoustic phonons, and acoustic phonon propagation then causes the growth of a thermally expanded layer. Source characterization is instrumental in utilizing ultrashort x-ray pulses in time-resolved x-ray spectroscopies. By measurement of the electron beam diameter at the generation point, the pulse duration of the Thomson scattered x-rays is determined. Analysis of the Thomson scattered x-ray beam properties also provides a novel means of electron bunch characterization. Although the pulse duration is inferred for the Thomson scattering x-ray source, direct measurement is required for other x-ray pulse sources. A method based on the laser-assisted photoelectric effect (LAPE) has been demonstrated as a

  2. Ultrashort X-ray pulse science

    International Nuclear Information System (INIS)

    Chin, A.H.; Lawrence Berkeley National Lab., CA

    1998-01-01

    A variety of phenomena involves atomic motion on the femtosecond time-scale. These phenomena have been studied using ultrashort optical pulses, which indirectly probe atomic positions through changes in optical properties. Because x-rays can more directly probe atomic positions, ultrashort x-ray pulses are better suited for the study of ultrafast structural dynamics. One approach towards generating ultrashort x-ray pulses is by 90 o Thomson scattering between terawatt laser pulses and relativistic electrons. Using this technique, the author generated ∼ 300 fs, 30 keV (0.4 (angstrom)) x-ray pulses. These x-ray pulses are absolutely synchronized with ultrashort laser pulses, allowing femtosecond optical pump/x-ray probe experiments to be performed. Using the right-angle Thomson scattering x-ray source, the author performed time-resolved x-ray diffraction studies of laser-perturbated InSb. These experiments revealed a delayed onset of lattice expansion. This delay is due to the energy relaxation from a dense electron-hole plasma to the lattice. The dense electron-hole plasma first undergoes Auger recombination, which reduces the carrier concentration while maintaining energy content. Longitudinal-optic (LO) phonon emission then couples energy to the lattice. LO phonon decay into acoustic phonons, and acoustic phonon propagation then causes the growth of a thermally expanded layer. Source characterization is instrumental in utilizing ultrashort x-ray pulses in time-resolved x-ray spectroscopies. By measurement of the electron beam diameter at the generation point, the pulse duration of the Thomson scattered x-rays is determined. Analysis of the Thomson scattered x-ray beam properties also provides a novel means of electron bunch characterization. Although the pulse duration is inferred for the Thomson scattering x-ray source, direct measurement is required for other x-ray pulse sources. A method based on the laser-assisted photoelectric effect (LAPE) has been

  3. Development of a Reference System for the determination of the personal dose equivalent and the constancy of X- Ray beams

    International Nuclear Information System (INIS)

    Vivolo, Vitor

    2006-01-01

    A reference system for the determination of the personal dose equivalent, Hp (10), and a quality control program of X-ray equipment used In radioprotection require the periodic verification of the X-ray beams constancy. In this work, two parallel-plate ionization chambers were developed with inner electrodes of different materials, and inserted into PMMA slab phantoms. One ionization chamber was developed with inner carbon electrodes and the other with inner aluminium electrodes. The two ionization chambers can be used as a Tandem system. The different energy response of the two ionization chambers allowed the development of the Tandem system that is very useful for the checking of the constancy of beam qualities. Standard intermediary energy X-ray beams (from 48 keV to 118 keV), radioprotection level, were established through the development of a dosimetric methodology and the analysis of their physical parameters. The ionization chambers were studied in relation to their operational characteristics, and they were calibrated in X-ray beams (radioprotection, diagnostic radiology, mammography and radiotherapy levels) in accordance to international recommendations. They presented good performance. The determination procedure of personal dose equivalent, Hp (10), was established. (author)

  4. A one-dimensional ion beam figuring system for x-ray mirror fabrication

    International Nuclear Information System (INIS)

    Idir, Mourad; Huang, Lei; Bouet, Nathalie; Kaznatcheev, Konstantine; Vescovi, Matthew; Lauer, Ken; Conley, Ray; Rennie, Kent; Kahn, Jim; Nethery, Richard; Zhou, Lin

    2015-01-01

    We report on the development of a one-dimensional Ion Beam Figuring (IBF) system for x-ray mirror polishing. Ion beam figuring provides a highly deterministic method for the final precision figuring of optical components with advantages over conventional methods. The system is based on a state of the art sputtering deposition system outfitted with a gridded radio frequency inductive coupled plasma ion beam source equipped with ion optics and dedicated slit developed specifically for this application. The production of an IBF system able to produce an elongated removal function rather than circular is presented in this paper, where we describe in detail the technical aspect and present the first obtained results

  5. A one-dimensional ion beam figuring system for x-ray mirror fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Idir, Mourad, E-mail: midir@bnl.gov; Huang, Lei; Bouet, Nathalie; Kaznatcheev, Konstantine; Vescovi, Matthew; Lauer, Ken [NSLS-II, Brookhaven National Laboratory, P.O. Box 5000, Upton, New York 11973 (United States); Conley, Ray [Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Rennie, Kent; Kahn, Jim; Nethery, Richard [Kaufman & Robinson, Inc., 1330 Blue Spruce Drive, Fort Collins, Colorado 80524 (United States); Zhou, Lin [College of Mechatronics and Automation, National University of Defense Technology, 109 Deya Road, Changsha, Hunan 410073 (China); Hu’nan Key Laboratory of Ultra-precision Machining Technology, Changsha, Hunan 410073 (China)

    2015-10-15

    We report on the development of a one-dimensional Ion Beam Figuring (IBF) system for x-ray mirror polishing. Ion beam figuring provides a highly deterministic method for the final precision figuring of optical components with advantages over conventional methods. The system is based on a state of the art sputtering deposition system outfitted with a gridded radio frequency inductive coupled plasma ion beam source equipped with ion optics and dedicated slit developed specifically for this application. The production of an IBF system able to produce an elongated removal function rather than circular is presented in this paper, where we describe in detail the technical aspect and present the first obtained results.

  6. Vertical beam size measurement in the CESR-TA e{sup +}e{sup −} storage ring using x-rays from synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, J.P.; Chatterjee, A.; Conolly, C.; Edwards, E.; Ehrlichman, M.P.; Fontes, E. [Cornell University, Ithaca, NY 14853 (United States); Heltsley, B.K., E-mail: bkh2@cornell.edu [Cornell University, Ithaca, NY 14853 (United States); Hopkins, W.; Lyndaker, A.; Peterson, D.P.; Rider, N.T.; Rubin, D.L.; Savino, J.; Seeley, R.; Shanks, J. [Cornell University, Ithaca, NY 14853 (United States); Flanagan, J.W. [High Energy Accelerator Research Organization (KEK), Tsukuba (Japan)

    2014-06-01

    We describe the construction and operation of an X-ray beam size monitor (xBSM), a device measuring e{sup +} and e{sup −} beam sizes in the CESR-TA storage ring using synchrotron radiation. The device can measure vertical beam sizes of 10–100μm on a turn-by-turn, bunch-by-bunch basis at e{sup ±} beam energies of ∼2GeV. At such beam energies the xBSM images X-rays of ϵ≈1–10keV (λ≈0.1–1nm) that emerge from a hard-bend magnet through a single- or multiple-slit (coded aperture) optical element onto an array of 32 InGaAs photodiodes with 50μm pitch. Beamlines and detectors are entirely in-vacuum, enabling single-shot beam size measurement down to below 0.1 mA (2.5×10{sup 9} particles) per bunch and inter-bunch spacing of as little as 4 ns. At E{sub b}=2.1GeV, systematic precision of ∼1μm is achieved for a beam size of ∼12μm; this is expected to scale as ∝1/σ{sub b} and ∝1/E{sub b}. Achieving this precision requires comprehensive alignment and calibration of the detector, optical elements, and X-ray beam. Data from the xBSM have been used to extract characteristics of beam oscillations on long and short timescales, and to make detailed studies of low-emittance tuning, intra-beam scattering, electron cloud effects, and multi-bunch instabilities.

  7. Tissue Equivalent Phantom Design for Characterization of a Coherent Scatter X-ray Imaging System

    Science.gov (United States)

    Albanese, Kathryn Elizabeth

    Scatter in medical imaging is typically cast off as image-related noise that detracts from meaningful diagnosis. It is therefore typically rejected or removed from medical images. However, it has been found that every material, including cancerous tissue, has a unique X-ray coherent scatter signature that can be used to identify the material or tissue. Such scatter-based tissue-identification provides the advantage of locating and identifying particular materials over conventional anatomical imaging through X-ray radiography. A coded aperture X-ray coherent scatter spectral imaging system has been developed in our group to classify different tissue types based on their unique scatter signatures. Previous experiments using our prototype have demonstrated that the depth-resolved coherent scatter spectral imaging system (CACSSI) can discriminate healthy and cancerous tissue present in the path of a non-destructive x-ray beam. A key to the successful optimization of CACSSI as a clinical imaging method is to obtain anatomically accurate phantoms of the human body. This thesis describes the development and fabrication of 3D printed anatomical scatter phantoms of the breast and lung. The purpose of this work is to accurately model different breast geometries using a tissue equivalent phantom, and to classify these tissues in a coherent x-ray scatter imaging system. Tissue-equivalent anatomical phantoms were designed to assess the capability of the CACSSI system to classify different types of breast tissue (adipose, fibroglandular, malignant). These phantoms were 3D printed based on DICOM data obtained from CT scans of prone breasts. The phantoms were tested through comparison of measured scatter signatures with those of adipose and fibroglandular tissue from literature. Tumors in the phantom were modeled using a variety of biological tissue including actual surgically excised benign and malignant tissue specimens. Lung based phantoms have also been printed for future

  8. Coherent scattering X-ray imaging at the Brazilian National Synchrotron Laboratory: Preliminary breast images

    Energy Technology Data Exchange (ETDEWEB)

    Castro, C.R.F. [Nuclear Instrumentation Laboratory-COPPE/UFRJ, P.O. Box 68509, Rio de Janeiro 21945-970 (Brazil); Barroso, R.C. [Physics Institute-University of Rio de Janeiro State, Rio de Janeiro 20559-900 (Brazil)]. E-mail: cely@uerij.br; Oliveira, L.F. de [Physics Institute-University of Rio de Janeiro State, Rio de Janeiro 20559-900 (Brazil); Lopes, R.T. [Nuclear Instrumentation Laboratory-COPPE/UFRJ, P.O. Box 68509, Rio de Janeiro 21945-970 (Brazil)

    2005-08-11

    The angular distribution of coherent scatter (low-momentum transfer) carries information about atomic structures, resulting in a pattern, which can be used to reconstruct a series of images. Coherent-scatter computed tomography is a novel imaging method developed to produce cross-sectional images based on the X-ray diffraction properties of an object. A different approach to coherent X-ray imaging is possible by fixing the detector at a given scatter angle {theta}, which produces an interference peak and then, carried out a tomography in the standard way. The cross-sectional images obtained allow determining the spatial dependence of coherent scatter cross-section of selected volume elements of inhomogeneous, extend objects for a single predetermined value of {theta} of interest, leading to a simplification of the data processing and the complexity of the apparatus. This work presents preliminary coherent scattering images carried out at the X-ray Diffraction beamline of the National Synchrotron Light Laboratory in Campinas, Brazil. The specimens were excised human breast tissues fixed in formaline. No frozen procedure was used in order to minimize preferred orientation during sample preparation. About 1mm thick slices cut from each of the fresh samples were mounted in frames without windows and placed on a translator to allow acquisition of scattering spectra. Cylinders containing healthy and cancerous (infiltrating ductal carcinoma) breast tissues were imagined at the characteristic angle for adipose tissue. Transmission and coherent scatter images are compared.

  9. Characterization of breast tissue using energy-dispersive X-ray diffraction computed tomography

    International Nuclear Information System (INIS)

    Pani, S.; Cook, E.J.; Horrocks, J.A.; Jones, J.L.; Speller, R.D.

    2010-01-01

    A method for sample characterization using energy-dispersive X-ray diffraction computed tomography (EDXRDCT) is presented. The procedures for extracting diffraction patterns from the data and the corrections applied are discussed. The procedures were applied to the characterization of breast tissue samples, 6 mm in diameter. Comparison with histological sections of the samples confirmed the possibility of grouping the patterns into five families, corresponding to adipose tissue, fibrosis, poorly differentiated cancer, well differentiated cancer and benign tumour.

  10. X-ray pulse wavefront metrology using speckle tracking

    International Nuclear Information System (INIS)

    Berujon, Sebastien; Ziegler, Eric; Cloetens, Peter

    2015-01-01

    The theoretical description and experimental implementation of a speckle-tracking-based instrument which permits the characterisation of X-ray pulse wavefronts. An instrument allowing the quantitative analysis of X-ray pulsed wavefronts is presented and its processing method explained. The system relies on the X-ray speckle tracking principle to accurately measure the phase gradient of the X-ray beam from which beam optical aberrations can be deduced. The key component of this instrument, a semi-transparent scintillator emitting visible light while transmitting X-rays, allows simultaneous recording of two speckle images at two different propagation distances from the X-ray source. The speckle tracking procedure for a reference-less metrology mode is described with a detailed account on the advanced processing schemes used. A method to characterize and compensate for the imaging detector distortion, whose principle is also based on speckle, is included. The presented instrument is expected to find interest at synchrotrons and at the new X-ray free-electron laser sources under development worldwide where successful exploitation of beams relies on the availability of an accurate wavefront metrology

  11. Micronuclei in human peripheral blood lymphocytes exposed to mixed beams of X-rays and alpha particles

    Czech Academy of Sciences Publication Activity Database

    Staaf, E.; Brehwens, K.; Haghdoost, S.; Nievaart, S.; Pachnerová Brabcová, Kateřina; Czub, J.; Braziewicz, J.; Wojcik, A.

    2012-01-01

    Roč. 51, č. 3 (2012), s. 283-293 ISSN 0301-634X Institutional research plan: CEZ:AV0Z10480505 Keywords : Micronuclei * LET * Combined exposure * Mixed beams * Alpha particles * X-rays Subject RIV: BO - Biophysics Impact factor: 1.754, year: 2012

  12. Toward a fourth-generation X-ray source

    International Nuclear Information System (INIS)

    Monction, D. E.

    1999-01-01

    The field of synchrotron radiation research has grown rapidly over the last 25 years due to both the push of the accelerator and magnet technology that produces the x-ray beams and the pull of the extraordinary scientific research that is possible with them. Three successive generations of synchrotrons radiation facilities have resulted in beam brilliances 11 to 12 orders of magnitude greater than the standard laboratory x-ray tube. However, greater advances can be easily imagined given the fact that x-ray beams from present-day facilities do not exhibit the coherence or time structure so familiar with the optical laser. Theoretical work over the last ten years or so has pointed to the possibility of generating hard x-ray beams with laser-like characteristics. The concept is based on self-amplified spontaneous emission (SASE) in flee-electron lasers. A major facility of this type based upon a superconducting linac could produce a cost-effective facility that spans wave-lengths from the ultraviolet to the hard x-ray regime, simultaneously servicing large numbers experimenters from a wide range of disciplines. As with each past generation of synchrotrons facilities, immense new scientific opportunities would result from fourth-generation sources.

  13. X-ray spectroscopy of hydrogen-like ions in an electron beam ion trap

    Energy Technology Data Exchange (ETDEWEB)

    Tarbutt, M.R.; Crosby, D.; Silver, J.D. [Univ. of Oxford, Clarendon Lab. (United Kingdom); Myers, E.G. [Dept. of Physics, Florida State Univ., Tallahassee, FL (United States); Nakamura, N.; Ohtani, S. [ICORP, JST, Chofu, Tokyo (Japan)

    2001-07-01

    The X-ray emission from highly charged hydrogen-like ions in an electron beam ion trap is free from the problems of satellite contamination and Doppler shifts inherent in fast-beam sources. This is a favourable situation for the measurement of ground-state Lamb shifts in these ions. We present recent progress toward this goal, and discuss a method whereby wavelength comparison between transitions in hydrogenlike ions of different nuclear charge Z, enable the measurement of QED effects without requiring an absolute calibration.

  14. Synchrotron x-ray fluorescence and extended x-ray absorption fine structure analysis

    International Nuclear Information System (INIS)

    Chen, J.R.; Gordon, B.M.; Hanson, A.L.; Jones, K.W.; Kraner, H.W.; Chao, E.C.T.; Minkin, J.A.

    1984-01-01

    The advent of dedicated synchrotron radiation sources has led to a significant increase in activity in many areas of science dealing with the interaction of x-rays with matter. Synchrotron radiation provides intense, linearly polarized, naturally collimated, continuously tunable photon beams, which are used to determine not only the elemental composition of a complex, polyatomic, dilute material but also the chemical form of the elements with improved accuracy. Examples of the application of synchrotron radiation include experiments in synchrotron x-ray fluorescence (SXRF) analysis and extended x-ray absorption fine structure (EXAFS) analysis. New synchrotron radiation x-ray microprobes for elemental analysis in the parts per billion range are under construction at several laboratories. 76 references, 24 figures

  15. Absorbed dose determination in water in medium energy x-ray beam

    International Nuclear Information System (INIS)

    Nisevic, G.; Spasic-Jokic, V.

    1998-01-01

    Absorbed dose determination in water phantom in medium energy X-ray beam, according to IAEA recommendations is given. This method is applied on Radiotherapy department of Military Academy Hospital in Belgrade. Reference points of measurements are on depth of 5 cm and 2 cm as it recommended in ref. Experimental results are shown in aim to introduce new dosimetric concept based on air kerma calibration factor recommended for application in our radiotherapy centers (author)

  16. SU-E-I-52: Effect of Various X-Ray Beam Qualities On the Exposure Index

    International Nuclear Information System (INIS)

    Yasumatsu, S; Iwase, K; Shimizu, Y; Tanaka, N; Morishita, J

    2015-01-01

    Purpose: The exposure index (EI) proposed by the International Electrotechnical Commission (IEC) 62494-1 is expected to be utilized as a standard dose index by every manufacturer. The IEC recommended the usage of RQA5 for the EI. However, X-ray beam qualities, particularly in clinical practices, vary depending on the examination objects and exposure conditions, including usage of anti-scatter grids. We investigated the effects of the X-ray beam qualities other than RQA5 on the EI. Methods: The Xray beam qualities of RQA3, 5, 7, and 9 in IEC 61267 Ed. 1.0 were adopted in a computed radiography system. A uniform exposure without objects was performed to measure the exposure indicators (S values) and air kerma (K). The relational equations between the S values and K were derived for the determination of the EI values. The EI values for RQA3, 7, and 9 were compared to those for RQA5 at the fixed S values of 100, 200, 400, and 600. Finally, the half-value layers (HVLs) using four grids (ratio 6:1, 8:1, 10:1, and 12:1) for the RQA5 X-ray were compared to those with RQA3–9. Results: The EI values for RQA3, 7, and 9 were up to 35.3%, 11.8%, and 38.7% higher, respectively, than that for RQA5 at the S value of 600. The HVLs without grids and with various grids for RQA5 were 6.85 mm Al. and in the range of 6.94–7.29 mm Al. (ΔHVL: up to 0.44 mm Al.), respectively. This variation in the HVLs with grids was smaller than that observed for RQA3–9 (ΔHVL: 2.0–7.5 mm Al.). Conclusion: Although the usage of grids may not greatly affect the EI, the X-ray beam quality for the determination of the EI cannot be ignored in the clinical evaluation of the dose index

  17. Relativistic self-focusing of ultra-high intensity X-ray laser beams in warm quantum plasma with upward density profile

    International Nuclear Information System (INIS)

    Habibi, M.; Ghamari, F.

    2014-01-01

    The results of a numerical study of high-intensity X-ray laser beam interaction with warm quantum plasma (WQP) are presented. By means of an upward ramp density profile combined with quantum factors specially the Fermi velocity, we have demonstrated significant relativistic self-focusing (RSF) of a Gaussian electromagnetic beam in the WQP where the Fermi temperature term in the dielectric function is important. For this purpose, we have considered the quantum hydrodynamics model that modifies refractive index of inhomogeneous WQPs with the inclusion of quantum correction through the quantum statistical and diffraction effects in the relativistic regime. Also, to better illustration of the physical difference between warm and cold quantum plasmas and their effect on the RSF, we have derived the envelope equation governing the spot size of X-ray laser beam in Q-plasmas. In addition to the upward ramp density profile, we have found that the quantum effects would be caused much higher oscillation and better focusing of X-ray laser beam in the WQP compared to that of cold quantum case. Our computational results reveal the importance of the use of electrons density profile and Fermi speed in enhancing self-focusing of laser beam

  18. Flash X-Ray (FXR) Accelerator Optimization Electronic Time-Resolved Measurement of X-Ray Source Size

    International Nuclear Information System (INIS)

    Jacob, J; Ong, M; Wargo, P

    2005-01-01

    Lawrence Livermore National Laboratory (LLNL) is currently investigating various approaches to minimize the x-ray source size on the Flash X-Ray (FXR) linear induction accelerator in order to improve x-ray flux and increase resolution for hydrodynamic radiography experiments. In order to effectively gauge improvements to final x-ray source size, a fast, robust, and accurate system for measuring the spot size is required. Timely feedback on x-ray source size allows new and improved accelerator tunes to be deployed and optimized within the limited run-time constraints of a production facility with a busy experimental schedule; in addition, time-resolved measurement capability allows the investigation of not only the time-averaged source size, but also the evolution of the source size, centroid position, and x-ray dose throughout the 70 ns beam pulse. Combined with time-resolved measurements of electron beam parameters such as emittance, energy, and current, key limiting factors can be identified, modeled, and optimized for the best possible spot size. Roll-bar techniques are a widely used method for x-ray source size measurement, and have been the method of choice at FXR for many years. A thick bar of tungsten or other dense metal with a sharp edge is inserted into the path of the x-ray beam so as to heavily attenuate the lower half of the beam, resulting in a half-light, half-dark image as seen downstream of the roll-bar; by measuring the width of the transition from light to dark across the edge of the roll-bar, the source size can be deduced. For many years, film has been the imaging medium of choice for roll-bar measurements thanks to its high resolution, linear response, and excellent contrast ratio. Film measurements, however, are fairly cumbersome and require considerable setup and analysis time; moreover, with the continuing trend towards all-electronic measurement systems, film is becoming increasingly difficult and expensive to procure. Here, we shall

  19. Providing x-rays

    International Nuclear Information System (INIS)

    Mallozzi, P.J.; Epstein, H.M.

    1985-01-01

    This invention provides an apparatus for providing x-rays to an object that may be in an ordinary environment such as air at approximately atmospheric pressure. The apparatus comprises: means (typically a laser beam) for directing energy onto a target to produce x-rays of a selected spectrum and intensity at the target; a fluid-tight enclosure around the target; means for maintaining the pressure in the first enclosure substantially below atmospheric pressure; a fluid-tight second enclosure adjoining the first enclosure, the common wall portion having an opening large enough to permit x-rays to pass through but small enough to allow the pressure reducing means to evacuate gas from the first enclosure at least as fast as it enters through the opening; the second enclosure filled with a gas that is highly transparent to x-rays; the wall of the second enclosure to which the x-rays travel having a portion that is highly transparent to x-rays (usually a beryllium or plastic foil), so that the object to which the x-rays are to be provided may be located outside the second enclosure and adjacent thereto and thus receive the x-rays substantially unimpeded by air or other intervening matter. The apparatus is particularly suited to obtaining EXAFS (extended x-ray fine structure spectroscopy) data on a material

  20. 50 μm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis

    International Nuclear Information System (INIS)

    Zhao, C; Kanicki, J; Konstantinidis, A C; Zheng, Y; Speller, R D; Anaxagoras, T

    2015-01-01

    Wafer-scale CMOS active pixel sensors (APSs) have been developed recently for x-ray imaging applications. The small pixel pitch and low noise are very promising properties for medical imaging applications such as digital breast tomosynthesis (DBT). In this work, we evaluated experimentally and through modeling the imaging properties of a 50 μm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). A modified cascaded system model was developed for CMOS APS x-ray detectors by taking into account the device nonlinear signal and noise properties. The imaging properties such as modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE) were extracted from both measurements and the nonlinear cascaded system analysis. The results show that the DynAMITe x-ray detector achieves a high spatial resolution of 10 mm −1 and a DQE of around 0.5 at spatial frequencies  <1 mm −1 . In addition, the modeling results were used to calculate the image signal-to-noise ratio (SNR i ) of microcalcifications at various mean glandular dose (MGD). For an average breast (5 cm thickness, 50% glandular fraction), 165 μm microcalcifications can be distinguished at a MGD of 27% lower than the clinical value (∼1.3 mGy). To detect 100 μm microcalcifications, further optimizations of the CMOS APS x-ray detector, image aquisition geometry and image reconstruction techniques should be considered. (paper)

  1. An extended range soft X-ray beam line for the 1 GeV storage ring Aladdin

    International Nuclear Information System (INIS)

    Hulbert, S.L.; Stott, J.P.; Brown, F.C.

    1983-01-01

    The design and implementation of a soft X-ray beam line on the new 1 GeV storage ring Aladdin in Stoughton, Wisconsin is discussed. The beam line consists of a long horizontally focussing collection mirror, an extended range (50-1500 eV) grasshopper monochromator, an ellipsoidal refocussing mirror, and a photoemission chamber. Also discussed are the factors considered in matching the monochromator to the storage ring, flux and performance expectations, and the results of a ray tracing analysis. (orig.)

  2. Evaluation of the BreastSimulator software platform for breast tomography

    Science.gov (United States)

    Mettivier, G.; Bliznakova, K.; Sechopoulos, I.; Boone, J. M.; Di Lillo, F.; Sarno, A.; Castriconi, R.; Russo, P.

    2017-08-01

    The aim of this work was the evaluation of the software BreastSimulator, a breast x-ray imaging simulation software, as a tool for the creation of 3D uncompressed breast digital models and for the simulation and the optimization of computed tomography (CT) scanners dedicated to the breast. Eight 3D digital breast phantoms were created with glandular fractions in the range 10%-35%. The models are characterised by different sizes and modelled realistic anatomical features. X-ray CT projections were simulated for a dedicated cone-beam CT scanner and reconstructed with the FDK algorithm. X-ray projection images were simulated for 5 mono-energetic (27, 32, 35, 43 and 51 keV) and 3 poly-energetic x-ray spectra typically employed in current CT scanners dedicated to the breast (49, 60, or 80 kVp). Clinical CT images acquired from two different clinical breast CT scanners were used for comparison purposes. The quantitative evaluation included calculation of the power-law exponent, β, from simulated and real breast tomograms, based on the power spectrum fitted with a function of the spatial frequency, f, of the form S(f)  =  α/f   β . The breast models were validated by comparison against clinical breast CT and published data. We found that the calculated β coefficients were close to that of clinical CT data from a dedicated breast CT scanner and reported data in the literature. In evaluating the software package BreastSimulator to generate breast models suitable for use with breast CT imaging, we found that the breast phantoms produced with the software tool can reproduce the anatomical structure of real breasts, as evaluated by calculating the β exponent from the power spectral analysis of simulated images. As such, this research tool might contribute considerably to the further development, testing and optimisation of breast CT imaging techniques.

  3. X-ray generator based on Compton scattering

    NARCIS (Netherlands)

    Androsov, V.P.; Agafonov, A.V.; Botman, J.I.M.; Bulyak, E.V.; Drebot, I.; Gladkikh, P.I.; Grevtsev, V.; Ivashchenko, V.; Karnaukhov, I.M.; Lapshin, V.I.

    2005-01-01

    Nowadays, the sources of the X-rays based on a storage ring with low beam energy and Compton scattering of intense laser beam are under development in several laboratories. In the paper the state-of-art in development and construction of cooperative project of a Kharkov advanced X-ray source NESTOR

  4. Scattered X-ray beam nondestructive testing

    International Nuclear Information System (INIS)

    Harding, G.; Kosanetzky, J.

    1988-01-01

    X-ray scatter interactions generally dominate the linear attenuation coefficient at the photon energies typical of medical and industrial radiography. Specific advantages of X-ray scatter imaging, including a flexible choice of measurement geometry, direct 3D-imaging capability (tomography) and improved information for material characterization, are illustrated with results from Compton and coherent scatter devices. Applications of a Compton backscatter scanner (ComScan) in the aerospace industry and coherent scatter imaging in security screening are briefly considered [pt

  5. Development of a Hard X-ray Beam Position Monitor for Insertion Device Beams at the APS

    Science.gov (United States)

    Decker, Glenn; Rosenbaum, Gerd; Singh, Om

    2006-11-01

    Long-term pointing stability requirements at the Advanced Photon Source (APS) are very stringent, at the level of 500 nanoradians peak-to-peak or better over a one-week time frame. Conventional rf beam position monitors (BPMs) close to the insertion device source points are incapable of assuring this level of stability, owing to mechanical, thermal, and electronic stability limitations. Insertion device gap-dependent systematic errors associated with the present ultraviolet photon beam position monitors similarly limit their ability to control long-term pointing stability. We report on the development of a new BPM design sensitive only to hard x-rays. Early experimental results will be presented.

  6. Spatial resolution in depth-controlled surface sensitive x-ray techniques

    International Nuclear Information System (INIS)

    Yun, W.B.; Viccaro, P.J.

    1992-01-01

    The spatial resolution along the surface normal and the total depth probed are two important parameters in depth-controlled surface sensitive X-ray techniques employing grazing incidence geometry. The two parameters are analyzed in terms of optical properties (refractive indices) of the media involved and parameters of the incident X-ray beam: beam divergence, X-ray energy, and spectral bandwidth. We derive analytical expressions of the required beam divergence and spectral bandwidth of the incident beam as a function of the two parameters. Sample calculations are made for X-ray energies between 0.1 and 100 keV and for solid Be, Cu, and Au, representing material matrices consisting of low, medium, and high atomic number elements. A brief discussion on obtaining the required beam divergence and spectral bandwidth from present X-ray sources and optics is given

  7. SU-D-209-02: Percent Depth Dose Curves for Fluoroscopic X-Ray Beam Qualities Incorporating Copper Filtration

    Energy Technology Data Exchange (ETDEWEB)

    Wunderle, K [Cleveland Clinic Foundation, Cleveland, OH (United States); Wayne State University School of Medicine, Detroit, MI (United States); Godley, A; Shen, Z; Dong, F [Cleveland Clinic Foundation, Cleveland, OH (United States); Rakowski, J [Wayne State University School of Medicine, Detroit, MI (United States)

    2016-06-15

    Purpose: The purpose of this investigation was to quantify percent depth dose (PDD) curves for fluoroscopic x-ray beam qualities incorporating added copper filtration. Methods: A PTW (Freiburg, Germany) MP3 water tank was used with a Standard Imaging (Middleton, WI) Exradin Model 11 Spokas Chamber to measure PDD curves for 60, 80, 100 and 120 kVp x-ray beams with copper filtration ranging from 0.0–0.9 mm at 22cm and 42cm fields of view from 0 to 150 mm of water. A free-in-air monitor chamber was used to normalize the water tank data to fluctuations in output from the fluoroscope. The measurements were acquired on a Siemens (Erlangen, Germany) Artis ZeeGo fluoroscope. The fluoroscope was inverted from the typical orientation providing an x-ray beam originating from above the water tank. The water tank was positioned so that the water level was located at 60cm from the focal spot; which also represents the focal spot to interventional reference plane distance for that fluoroscope. Results: PDDs for 60, 80, 100, and 120 kVp with 0 mm of copper filtration compared well to previously published data by Fetterly et al. [Med Phys, 28, 205 (2001)] for those beam qualities given differences in fluoroscopes, geometric orientation, type of ionization chamber, and the water tank used for data collection. PDDs for 60, 80, 100, and 120 kVp with copper filtration were obtained and are presented, which have not been previously investigated and published. Conclusion: The equipment and processes used to acquire the reported data were sound and compared well with previously published data for PDDs without copper filtration. PDD data for the fluoroscopic x-ray beams incorporating copper filtration can be used as reference data for estimating organ or soft tissue dose at depth involving similar beam qualities or for comparison with mathematical models.

  8. Radiation processing with high-energy X-rays

    International Nuclear Information System (INIS)

    Cleland, Marshall R.; Stichelbaut, Frederic

    2009-01-01

    The physical, chemical or biological characteristics of selected commercial products and materials can be improved by radiation processing. The ionizing energy can be provided by accelerated electrons with energies between 75 keV and 10 MeV, gamma rays from cobalt-60 with average energies of 1.25 MeV or X-rays with maximum energies up to 7.5 MeV. Electron beams are preferred for thin products, which are processed at high speeds. Gamma rays are used for products that are too thick for treatment with electron beams. High-energy X-rays can also be used for these purposes because their penetration in solid materials is similar to or even slightly greater than that of gamma rays. Previously, the use of X-rays had been inhibited by their slower processing rates and higher costs when compared with gamma rays. Since then, the price of cobalt-60 sources has been increased and the radiation intensity from high-energy, high-power X-ray generators has also increased. For facilities requiring at least 2 MCi of cobalt-60, the capital and operating costs of X-ray facilities with equivalent processing rates can be less than that of gamma-ray irradiators. Several high-energy electron beam facilities have been equipped with removable X-ray targets so that irradiation processes can be done with either type of ionizing energy. A new facility is now being built which will be used exclusively in the X-ray mode to sterilize medical products. Operation of this facility will show that high-energy, high-power X-ray generators are practical alternatives to large gamma-ray sources. (author)

  9. White beam synchrotron x-ray topography of gallium arsenide

    International Nuclear Information System (INIS)

    Winter, J.M. Jr.; Green, R.E. Jr.; Corak, W.S.

    1988-01-01

    The defect structure of gallium arsenide was investigated using white beam transmission topography. The samples were cut and polished monocrystal substrates from different suppliers. The goal of the work was to determine the viability of the method for documenting various crystallographic defect structures and establishing their effect on the performance of integrated microwave circuits fabricated on the wafers. The principles of the technique, essentially identical to classical Laue x-ray diffraction, are outlined. Two distinct defect structures were determined in the topographs. Reasons for the defect structures were postulated and the application of the method for quality control assessments of manufacturer-supplied gallium arsenide substrates was assessed

  10. Electron cyclotron resonance ion source plasma characterization by X-ray spectroscopy and X-ray imaging

    Energy Technology Data Exchange (ETDEWEB)

    Mascali, David, E-mail: davidmascali@lns.infn.it; Castro, Giuseppe; Celona, Luigi; Neri, Lorenzo; Gammino, Santo [INFN–Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); Biri, Sándor; Rácz, Richárd; Pálinkás, József [Institute for Nuclear Research (Atomki), Hungarian Academy of Sciences, Bem tér 18/c, H-4026 Debrecen (Hungary); Caliri, Claudia [INFN–Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); Università degli Studi di Catania, Dip.to di Fisica e Astronomia, via Santa Sofia 64, 95123 Catania (Italy); Romano, Francesco Paolo [INFN–Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); CNR, Istituto per i Beni Archeologici e Monumentali, Via Biblioteca 4, 95124 Catania (Italy); Torrisi, Giuseppe [INFN–Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy); Università Mediterranea di Reggio Calabria, DIIES, Via Graziella, I-89100 Reggio Calabria (Italy)

    2016-02-15

    An experimental campaign aiming to investigate electron cyclotron resonance (ECR) plasma X-ray emission has been recently carried out at the ECRISs—Electron Cyclotron Resonance Ion Sources laboratory of Atomki based on a collaboration between the Debrecen and Catania ECR teams. In a first series, the X-ray spectroscopy was performed through silicon drift detectors and high purity germanium detectors, characterizing the volumetric plasma emission. The on-purpose developed collimation system was suitable for direct plasma density evaluation, performed “on-line” during beam extraction and charge state distribution characterization. A campaign for correlating the plasma density and temperature with the output charge states and the beam intensity for different pumping wave frequencies, different magnetic field profiles, and single-gas/gas-mixing configurations was carried out. The results reveal a surprisingly very good agreement between warm-electron density fluctuations, output beam currents, and the calculated electromagnetic modal density of the plasma chamber. A charge-coupled device camera coupled to a small pin-hole allowing X-ray imaging was installed and numerous X-ray photos were taken in order to study the peculiarities of the ECRIS plasma structure.

  11. EFFECTS OF X-RAY BEAM ANGLE AND GEOMETRIC DISTORTION ON WIDTH OF EQUINE THORACOLUMBAR INTERSPINOUS SPACES USING RADIOGRAPHY AND COMPUTED TOMOGRAPHY

    DEFF Research Database (Denmark)

    Djernaes, Julie D.; Nielsen, Jon V.; Berg, Lise C.

    2017-01-01

    The widths of spaces between the thoracolumbar processi spinosi (interspinous spaces) are frequently assessed using radiography in sports horses; however effects of varying X-ray beam angles and geometric distortion have not been previously described. The aim of this prospective, observational...... study was to determine whether X-ray beam angle has an effect on apparent widths of interspinous spaces. Thoracolumbar spine specimens were collected from six equine cadavers and left-right lateral radiographs and sagittal and dorsal reconstructed computed tomographic (CT) images were acquired...... measurements. Effect of geometric distortion was evaluated by comparing the interspinous space in radiographs with sagittal and dorsal reconstructed CT images. A total of 49 interspinous spaces were sampled, yielding 274 measurements. X-ray beam angle significantly affected measured width of interspinous...

  12. Characteristic parameters analysis on diagnostic X-ray beams for dosemeter calibration

    International Nuclear Information System (INIS)

    Oliveira, Paulo Marcio Campos de

    2008-01-01

    Ionizing radiation metrology is the base to achieve reliable dose measurements in ali areas; it is also part of the framework that is established to assure radiation protection procedures in order to avoid or minimize the harmful biological effect that may be caused by ionizing radiation. A well done metrology means the use of reliable instruments that comply with standard performance requirements worldwide accepted. Those instruments are expected to be calibrated by Metrology Laboratories under well defined conditions. The International Electrotechnical Commission (IEC) in Standard 61267 established the reference radiations for medical diagnostic x-ray equipment that are recommended to be used for calibrating dosimetric systems for diagnostic dosimetry. In this work, X-ray beam qualities were established in a Calibration Laboratory and their characteristics were analyzed through the measurement of beam parameters like inherent tube filtration, beam uniformity and field size, energy spectra and peak voltage for additional filtration with 94.425 por cent and 99.999 por cent purity filters. Also, the first half-value layer and the homogeneity coefficient were measured for the three RQR 2, RQR 6 and RQR 10 IEC beam qualities and they were analyzed according to the IEC standard. Air-kerma measurements were carried out with an ionization chamber that had its reliability confirmed through repetition and reproducibility reading tests. In 50 sets of measurements the maximum standard deviation found of 10 successive readings was 0.19 %; the maximum shift of the reading mean value at a fixed geometry condition was 0.80 % with an overall standard deviation of 0.23 %. Results showed that the use of different purity filters did not cause a relevant influence on the beam energy spectra. An ionization chamber was also calibrated against a standard dosimeter in ali implemented reference radiations and the relevant sources of uncertainties were estimated. Calibration could be done

  13. Scintillating ribbon x-ray detector

    International Nuclear Information System (INIS)

    Kinchen, B.E.; Rogers, A.

    1995-01-01

    A patent in the early 1970's by Aerojet Corporation in Sacramento, CA put forth the idea of using an array of scintillating fibers for x-ray detection and imaging. In about 1975, Pratt and Whitney Aircraft in East Hartford, CT designed and manufactured an imaging system based on the patent. The device was 1.75 in thick in the direction of the x-ray beam and about 4 in. by 4 in. square. The device was used with a 8 MeV x-ray source to image and measure internal clearances within operating aircraft, gas turbines engines. There are significant advantages of fiber optic detectors in x-ray detection. However, the advantages are often outweighed by the disadvantages. Two of the advantages of scintillating fiber optic x-ray detectors are: (1) high limiting spatial frequency -- between 20 and 25 lp/mm; and (2) excellent x-ray stopping power -- they can be made thick and retain spatial resolution. In traditional fiber optic detectors the x-rays are oriented parallel to the long axis of the fiber. For the scintillating ribbon x-ray sensor, the x-rays are oriented normal to the fiber long axis. This ribbon sensor technique has a number of advantages over the two current radiographic techniques digital x-radiography and x-ray film: The main advantage the ribbon has is size and shape. It can be as thin as 0.05 in., virtually any width or length, and flexible. Once positioned in a given location, 20 to 100 square inches of the object being inspected can be imaged with a single x-ray beam sweep. It is clear that conventional digital cameras do not lend themselves to placement between walls of aircraft structures or similar items requiring x-ray inspections. A prototype scintillating ribbon x-ray sensor has been fabricated and tested by Synergistic Detector Designs. Images were acquired on corrosion test panels of aluminum fabricated by Iowa State University

  14. Fabrication techniques of X-ray spiral zone plates

    International Nuclear Information System (INIS)

    Gao Nan; Zhu Xiaoli; Li Hailiang; Xie Changqing

    2010-01-01

    The techniques to make X-ray spiral zone plates using electron beam and X-ray lithography were studied. A master mask was fabricated on polyimide membrane by E-beam lithography and micro-electroplating. Spiral zone plates were efficiently replicated by X-ray lithography and micro-electroplating. By combining the techniques, spiral zone plates at 1 keV were successfully fabricate. With an outermost zone width of the 200 nm, and the gold absorbers thickness of 700 nm, the high quality zone plates can be used for X-ray phase contrast microscopy.(authors)

  15. Guides for intraoral x-rays

    International Nuclear Information System (INIS)

    Ogunsunlade, O.A.

    1988-01-01

    An h-shaped exterior guide for use in combination with a SNAP-A-RAY film holder for accurately aligning a beam from an X-ray cone with an X-ray film during the process of taking intraoral periapical dental X-rays of the maxillary and mandibular teeth is described comprising: a first guide arm laterally and detachably connectable through a housing means; a traverse arm extending from the midpoint of the first guide arm and parallel to the X-ray film; and a second guide arm extending perpendicularly from an end of the traverse arm toward a plane of the X-ray film and in parallel relation up to an end point of the first guide arm

  16. Impact of polychromatic x-ray sources on helical, cone-beam computed tomography and dual-energy methods

    International Nuclear Information System (INIS)

    Sidky, Emil Y; Zou Yu; Pan Xiaochuan

    2004-01-01

    Recently, there has been much work devoted to developing accurate and efficient algorithms for image reconstruction in helical, cone-beam computed tomography (CT). Little attention, however, has been directed to the effect of physical factors on helical, cone-beam CT image reconstruction. This work investigates the effect of polychromatic x-rays on image reconstruction in helical, cone-beam computed tomography. A pre-reconstruction dual-energy technique is developed to reduce beam-hardening artefacts and enhance contrast in soft tissue

  17. X-ray phase contrast imaging at MAMI

    International Nuclear Information System (INIS)

    El-Ghazaly, M.; Backe, H.; Lauth, W.; Kube, G.; Kunz, P.; Sharafutdinov, A.; Weber, T.

    2006-01-01

    Experiments have been performed to explore the potential of the low emittance 855 MeV electron beam of the Mainz Microtron MAMI for imaging with coherent X-rays. Transition radiation from a micro-focused electron beam traversing a foil stack served as X-ray source with good transverse coherence. Refraction contrast radiographs of low absorbing materials, in particular polymer strings with diameters between 30 and 450 μm, were taken with a polychromatic transition radiation X-ray source with a spectral distribution in the energy range between 8 and about 40 keV. The electron beam spot size had standard deviation σ h =(8.6±0.1) μm in the horizontal and σ v =(7.5±0.1) μm in the vertical direction. X-ray films were used as detectors. The source-to-detector distance amounted to 11.4 m. The objects were placed in a distance of up to 6m from the X-ray film. Holograms of strings were taken with a beam spot size σ v =(0.50±0.05) μm in vertical direction, and a monochromatic X-ray beam of 6keV energy. A good longitudinal coherence has been obtained by the (111) reflection of a flat silicon single crystal in Bragg geometry. It has been demonstrated that a direct exposure CCD chip with a pixel size of 13 x 13 μm 2 provides a highly efficient on-line detector. Contrast images can easily be generated with a complete elimination of all parasitic background. The on-line capability allows a minimization of the beam spot size by observing the smallest visible interference fringe spacings or the number of visible fringes. It has been demonstrated that X-ray films are also very useful detectors. The main advantage in comparison with the direct exposure CCD chip is the resolution. For the Structurix D3 (Agfa) X-ray film the standard deviation of the resolution was measured to be σ f =(1.2±0.4) μm, which is about a factor of 6 better than for the direct exposure CCD chip. With the small effective X-ray spot size in vertical direction of σ v =(1.2±0.3)μm and a

  18. X-ray phase contrast imaging at MAMI

    Energy Technology Data Exchange (ETDEWEB)

    El-Ghazaly, M.; Backe, H.; Lauth, W.; Kube, G.; Kunz, P.; Sharafutdinov, A.; Weber, T. [Universitaet Mainz, Institut fuer Kernphysik, Mainz (Germany)

    2006-05-15

    Experiments have been performed to explore the potential of the low emittance 855 MeV electron beam of the Mainz Microtron MAMI for imaging with coherent X-rays. Transition radiation from a micro-focused electron beam traversing a foil stack served as X-ray source with good transverse coherence. Refraction contrast radiographs of low absorbing materials, in particular polymer strings with diameters between 30 and 450 {mu}m, were taken with a polychromatic transition radiation X-ray source with a spectral distribution in the energy range between 8 and about 40 keV. The electron beam spot size had standard deviation {sigma}{sub h}=(8.6{+-}0.1) {mu}m in the horizontal and {sigma}{sub v}=(7.5{+-}0.1) {mu}m in the vertical direction. X-ray films were used as detectors. The source-to-detector distance amounted to 11.4 m. The objects were placed in a distance of up to 6m from the X-ray film. Holograms of strings were taken with a beam spot size {sigma}{sub v}=(0.50{+-}0.05) {mu}m in vertical direction, and a monochromatic X-ray beam of 6keV energy. A good longitudinal coherence has been obtained by the (111) reflection of a flat silicon single crystal in Bragg geometry. It has been demonstrated that a direct exposure CCD chip with a pixel size of 13 x 13 {mu}m{sup 2} provides a highly efficient on-line detector. Contrast images can easily be generated with a complete elimination of all parasitic background. The on-line capability allows a minimization of the beam spot size by observing the smallest visible interference fringe spacings or the number of visible fringes. It has been demonstrated that X-ray films are also very useful detectors. The main advantage in comparison with the direct exposure CCD chip is the resolution. For the Structurix D3 (Agfa) X-ray film the standard deviation of the resolution was measured to be {sigma}{sub f}=(1.2{+-}0.4) {mu}m, which is about a factor of 6 better than for the direct exposure CCD chip. With the small effective X-ray spot size

  19. X-ray induced formation of γ-H2AX foci after full-field digital mammography and digital breast-tomosynthesis.

    Directory of Open Access Journals (Sweden)

    Siegfried A Schwab

    Full Text Available PURPOSE: To determine in-vivo formation of x-ray induced γ-H2AX foci in systemic blood lymphocytes of patients undergoing full-field digital mammography (FFDM and to estimate foci after FFDM and digital breast-tomosynthesis (DBT using a biological phantom model. MATERIALS AND METHODS: The study complies with the Declaration of Helsinki and was performed following approval by the ethic committee of the University of Erlangen-Nuremberg. Written informed consent was obtained from every patient. For in-vivo tests, systemic blood lymphocytes were obtained from 20 patients before and after FFDM. In order to compare in-vivo post-exposure with pre-exposure foci levels, the Wilcoxon matched pairs test was used. For in-vitro experiments, isolated blood lymphocytes from healthy volunteers were irradiated at skin and glandular level of a porcine breast using FFDM and DBT. Cells were stained against the phosphorylated histone variant γ-H2AX, and foci representing distinct DNA damages were quantified. RESULTS: Median in-vivo foci level/cell was 0.086 (range 0.067-0.116 before and 0.094 (0.076-0.126 after FFDM (p = 0.0004. In the in-vitro model, the median x-ray induced foci level/cell after FFDM was 0.120 (range 0.086-0.140 at skin level and 0.035 (range 0.030-0.050 at glandular level. After DBT, the median x-ray induced foci level/cell was 0.061 (range 0.040-0.081 at skin level and 0.015 (range 0.006-0.020 at glandular level. CONCLUSION: In patients, mammography induces a slight but significant increase of γ-H2AX foci in systemic blood lymphocytes. The introduced biological phantom model is suitable for the estimation of x-ray induced DNA damages in breast tissue in different breast imaging techniques.

  20. X-ray diffraction imaging with the Multiple Inverse Fan Beam topology: Principles, performance and potential for security screening

    Energy Technology Data Exchange (ETDEWEB)

    Harding, G., E-mail: Geoffrey.Harding@Morphodetection.com [Morpho Detection Germany GmbH, Heselstuecken 3, 22453 Hamburg (Germany); Fleckenstein, H.; Kosciesza, D.; Olesinski, S.; Strecker, H.; Theedt, T.; Zienert, G. [Morpho Detection Germany GmbH, Heselstuecken 3, 22453 Hamburg (Germany)

    2012-07-15

    The steadily increasing number of explosive threat classes, including home-made explosives (HMEs), liquids, amorphous and gels (LAGs), is forcing up the false-alarm rates of security screening equipment. This development can best be countered by increasing the number of features available for classification. X-ray diffraction intrinsically offers multiple features for both solid and LAGs explosive detection, and is thus becoming increasingly important for false-alarm and cost reduction in both carry-on and checked baggage security screening. Following a brief introduction to X-ray diffraction imaging (XDI), which synthesizes in a single modality the image-forming and material-analysis capabilities of X-rays, the Multiple Inverse Fan Beam (MIFB) XDI topology is described. Physical relationships obtaining in such MIFB XDI components as the radiation source, collimators and room-temperature detectors are presented with experimental performances that have been achieved. Representative X-ray diffraction profiles of threat substances measured with a laboratory MIFB XDI system are displayed. The performance of Next-Generation (MIFB) XDI relative to that of the 2nd Generation XRD 3500{sup TM} screener (Morpho Detection Germany GmbH) is assessed. The potential of MIFB XDI, both for reducing the exorbitant cost of false alarms in hold baggage screening (HBS), as well as for combining 'in situ' liquid and solid explosive detection in carry-on luggage screening is outlined. - Highlights: Black-Right-Pointing-Pointer X-ray diffraction imaging (XDI) synthesizes analysis and imaging in one x-ray modality. Black-Right-Pointing-Pointer A novel XDI beam topology comprising multiple inverse fan-beams (MIFB) is described. Black-Right-Pointing-Pointer The MIFB topology is technically easy to realize and has high photon collection efficiency. Black-Right-Pointing-Pointer Applications are envisaged in checkpoint, hold baggage and cargo screening.

  1. New imaging technique based on diffraction of a focused x-ray beam

    Energy Technology Data Exchange (ETDEWEB)

    Kazimirov, A [Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, NY 14853 (United States); Kohn, V G [Russian Research Center ' Kurchatov Institute, 123182 Moscow (Russian Federation); Cai, Z-H [Advanced Photon Source, 9700 S. Cass Avenue, Argonne, IL 60439 (United States)], E-mail: ayk7@cornell.edu

    2009-01-07

    We present first experimental results from a new diffraction depth-sensitive imaging technique. It is based on the diffraction of a focused x-ray beam from a crystalline sample and recording the intensity pattern on a high-resolution CCD detector positioned at a focal plane. Structural non-uniformity inside the sample results in a region of enhanced intensity in the diffraction pattern. The technique was applied to study silicon-on-insulator thin layers of various thicknesses which revealed a complex strain profile within the layers. A circular Fresnel zone plate was used as a focusing optic. Incoherent diffuse scattering spreads out of the diffraction plane and results in intensity recorded outside of the focal spot providing a new approach to separately register x-rays scattered coherently and incoherently from the sample. (fast track communication)

  2. Evaluation of the spectral distribution of X-ray beams from measurements on the scattered radiation

    International Nuclear Information System (INIS)

    Casnati, E.; Baraldi, C.

    1980-01-01

    Most of the phenomena activated by photons with energies below 100 keV show an apparent or real dependence on the quantum energy. Therefore, knowledge of the beam energy characteristics is of primary importance for interpretation of the irradiation results. The greatest difficulty arises from the high flux density of the beams usually employed which does not allow direct measurements of the beam. A method was developed which permits evaluation of the spectral distribution of the X-ray beam from a spectrometric measurement of the radiation scattered by a thin foil of a suitable metal. This makes possible a new and more rational approach to the measurement of X-rays in the energy range where the interaction parameters show a large photon energy dependence. The corrections required by the presence of some collateral effects, among which the most important is the coexistence of the coherent and incoherent scattering, must be evaluated. The knowledge of the spectral distribution is of immediate usefulness for studies of radiation damage in biological and other materials, for the calibration of radiation measuring instruments and for the improvement of the radiological instrumentation response which contributes to reducing the patient's dose. (H.K.)

  3. Dose reduction by x-ray beam filtration in screen-film radiography

    International Nuclear Information System (INIS)

    Koedooder, C.

    1986-01-01

    This thesis describes experimental and theoretical aspects of dose reduction by x-ray beam filtration in screen-film radiography. The thesis deals mainly with dose reduction under the constraint of constant image quality; an analytical approach is chosen. Therefore, part of the thesis deals with the development of an algorithm to calculate patient dose and exposure for different filter materials and different tube load conditions, under the constraint of constant contrast and constant optical density. (Auth.)

  4. Measure of the attenuation curve of a beam of X-rays with TLD-100 dosimeters of LiF

    International Nuclear Information System (INIS)

    Bonzi, E. V.; Mainardi, R. T.; Germanier, A.; Delgado, V.

    2011-10-01

    The attenuation curve of a beam of X-rays represents the beam intensity in function of the attenuator thickness interposed between the source and the detector. To know with the major possible precision the attenuation curve is indispensable in procedures of spectral reconstruction. Their periodic measuring also offers valuable information on the correct operation of a tube of X-rays, diagnostic or therapy, when not have a specific detector for that activity. In this work was measured the attenuation curve of a tube of X-rays operated to 50 kV and 0.5 ma, using existent elements in any diagnostic or therapy laboratory with radiations. In the measures commercial aluminum foil was used, bent until 24 times and thermoluminescent dosimeters TLD 100 - LiF. Also, for comparison, was measured this attenuation curve with an ionization chamber brand Capintec model 192. Was determined by X-rays fluorescence the composition of the aluminium foil, since the present elements in the alloy can to affect the form of the attenuation curve. It is interesting to observe that these elements are in very low proportion (ppm) that they do not alter the attenuation capacity of the pure aluminium. Finally in a precision balance we weigh a big piece (30 cm x 100 cm) of aluminium foil and we obtained the thickness in g/c m2. It is possible to obtain attenuation curves of a beam of X-rays, with a high precision procedure and reproducibility. The use of TLD-100 dosimeters of LiF or similar makes that this activity was also quick and simple. (Author)

  5. The development and operation of a method for the remote determination of X-ray beam parameters used in dental radiography

    International Nuclear Information System (INIS)

    Hewitt, J.M.

    1984-07-01

    The method described is a part of the Dental Monitoring Service operated by the Board in the UK for the assessment of radiation protection in dental practice. This postal service, which provides a comprehensive survey of dental X-ray sets and radiographic procedures, is undertaken by means of a questionnaire, film cassettes for exposure to the X-ray set and a personal monitoring component to check operator doses. The film cassettes and the methods by which the X-ray beam parameters are obtained are described in detail. The cassettes use radiation monitoring film to realise, by means of measurements of relative transmission through selected copper filters, the extended dynamic range of exposure necessary for accurate indication of the operating kilovoltage and total beam filtration. The standard of the X-ray unit with regard to the relevant regulations and code of practice can then be assessed, and, from the values of radiation dose determined for chosen exposure times, exposure settings for optimum quality radiographs can be recommended where appropriate. Although designed primarily for dental X-ray units, use of the film cassette package may be extended, with suitable calibration, to general diagnostic X-ray survey measurements. (author)

  6. X-ray study of a test quadrant of the SODART telescopes using the expanded beam x-ray optics facility at the Daresbury synchrotron

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Hornstrup, Allan; Frederiksen, P.

    1994-01-01

    The imaging properties of a test model of the SODART telescopes have been studied using an expanded beam X-ray facility at the Daresbury synchrotron. The encircled power and the point spread function at three energies 6.627 keV, 8.837 keV and 11.046 keV have been measured using 1D and 2D position...

  7. New x-ray parallel beam facility XPBF 2.0 for the characterization of silicon pore optics

    Science.gov (United States)

    Krumrey, Michael; Müller, Peter; Cibik, Levent; Collon, Max; Barrière, Nicolas; Vacanti, Giuseppe; Bavdaz, Marcos; Wille, Eric

    2016-07-01

    A new X-ray parallel beam facility (XPBF 2.0) has been installed in the laboratory of the Physikalisch-Technische Bundesanstalt at the synchrotron radiation facility BESSY II in Berlin to characterize silicon pore optics (SPOs) for the future X-ray observatory ATHENA. As the existing XPBF which is operated since 2005, the new beamline provides a pencil beam of very low divergence, a vacuum chamber with a hexapod system for accurate positioning of the SPO to be investigated, and a vertically movable CCD-based camera system to register the direct and the reflected beam. In contrast to the existing beamline, a multilayer-coated toroidal mirror is used for beam monochromatization at 1.6 keV and collimation, enabling the use of beam sizes between about 100 μm and at least 5 mm. Thus the quality of individual pores as well as the focusing properties of large groups of pores can be investigated. The new beamline also features increased travel ranges for the hexapod to cope with larger SPOs and a sample to detector distance of 12 m corresponding to the envisaged focal length of ATHENA.

  8. Blade-type X-ray beam position monitors for SPring-8 undulator beamlines

    CERN Document Server

    Aoyagi, H; Kitamura, H

    2001-01-01

    The X-ray beam position monitors had been designed and installed for SPring-8 insertion device beamlines. These monitors are being utilized for photon beam diagnostics. The beam from the standard undulator in SPring-8 has the total power of 11 kW and the power density of 470 kW/mrad sup 2 , typically. Each monitor has four CVD diamond blades coated with metal for detector heads. We have already introduced three styles of monitors to match various insertion devices in SPring-8. A standard style, or a fixed-blade style, is used mainly for a standard in-vacuum undulator beamlines. A horizontal-blade-drive style and a four-blade-drive style are used for beamlines of a wiggler and a twin helical undulator that have wide power distributions, and for figure-8 undulators that have asymmetric power distributions, respectively. This report describes the design and the structure of these monitors and the beam-tests for the photon beam diagnostics in detail.

  9. A method for measuring the time structure of synchrotron x-ray beams

    International Nuclear Information System (INIS)

    Moses, W.W.; Derenzo, S.E.

    1989-08-01

    We describe a method employing a plastic scintillator coupled to a fast photomultiplier tube to generate a timing pulse from the x-ray bursts emitted from a synchrotron radiation source. This technique is useful for performing synchrotron experiments where detailed knowledge of the timing distribution is necessary, such as time resolved spectroscopy or fluorescence lifetime experiments. By digitizing the time difference between the timing signal generated on one beam crossing with the timing signal generated on the next beam crossing, the time structure of a synchrotron beam can be analyzed. Using this technique, we have investigated the single bunch time structure at the National Synchrotron Light Source (NSLS) during pilot runs in January, 1989, and found that the majority of the beam (96%) is contained in one rf bucket, while the remainder of the beam (4%) is contained in satellite rf buckets preceeding and following the main rf bucket by 19 ns. 1 ref., 4 figs

  10. TH-AB-209-11: Breast Microcalcification Classification Using Spectral X-Ray Coherent Scatter Computed Tomography

    Energy Technology Data Exchange (ETDEWEB)

    Ghammraoui, B; M Popescu, L; Badano, A [Food & Drug Administration, Silver Spring, MD (United States)

    2016-06-15

    Purpose: To investigate the ability of Coherent Scatter Computed Tomography (CSCT) to distinguish non-invasively between type I calcifications, consisting of calcium oxalate dihydrate (CO) compounds which are more often associated with benign lesions, and type II calcifications containing hydroxyapatite (HA) which are predominantly associated with malignant tumors. Methods: The coherent scatter cross sections of HA and CO were measured using an energy dispersive x-ray diffractometer. The measured cross sections were introduced into MC-GPU Monte Carlo simulation code for studying the applicability of CSCT to discriminate between the two types of microcalcifications within the whole breast. Simulations were performed on a virtual phantom with inserted HA and CO spots of different sizes and placed in regions of interest having different background compositions. We considered a polychromatic x-ray source and an energy resolving photon counting detector. We applied an algorithm that estimates scatter components in projection space in order to obtain material-specific images of the breast. As material components adipose, glandular, HA and CO were used. The relative contrast of HA and CO components were used for type I and type II microcalcification discrimination. Results: The reconstructed CSCT images showed material-specific component-contrast values, with the highest CO or HA component contrast corresponding generally to the actual CO or HA feature, respectively. The discrimination performance varies with the x-ray intensity, calcification size, and background composition. The results were summarized using receiver operating characteristic (ROC) analysis with the area under the curve (AUC) taken as an overall indicator of discrimination performance and showing high AUC values up to unity. Conclusion: The simulation results obtained for a uniform breast imaging phantom indicate that CSCT has potential to be used as a non-invasive method for discrimination between type

  11. High-intensity laser synchrotron x-ray source

    International Nuclear Information System (INIS)

    Pogorelsky, I.V.

    1995-10-01

    A laser interacting with a relativistic electron beam behaves like a virtual wiggler of an extremely short period equal to half of the laser wavelength. This approach opens a route to relatively compact, high-brightness x-ray sources alternative or complementary to conventional synchrotron light sources. Although not new, the Laser Synchrotron Light Source (LSLS) concept is still waiting for a convincing demonstration. Available at the BNL's Accelerator Test Facility (ATF), a high-brightness electron beam and the high-power C0 2 laser may be used as prototype LSLS brick stones. In a feasible demonstration experiment, 10-GW, 100-ps C0 2 laser beam will be brought to a head-on collision with a 10-ps, 0.5-nC, 70 MeV electron bunch. Flashes of well-collimated, up to 9.36-keV (∼ Angstrom) x-rays of 10-ps pulse duration, with a flux of ∼10 19 photons/sec will be produced via linear Compton backscattering. The x-ray spectrum is tunable proportionally to a variable e-beam energy. A natural short-term extension of the proposed experiment would be further enhancement of the x-ray flux to a 10 21 -10 22 photons/sec level, after the ongoing ATF CO 2 laser upgrade to 1 TW peak power and electron bunch shortening to 3 ps. The ATF LSLS x-ray beamline, exceeding by orders of magnitude the peak fluxes attained at the National Synchrotron Light Source (NSLS) x-ray storage ring, may become attractive for certain users, e.g., for biological x-ray microscopy. In addition, a terawatt CO 2 laser will enable harmonic multiplication of the x-ray spectrum via nonlinear Compton scattering

  12. X-ray phase contrast imaging at MAMI

    Science.gov (United States)

    El-Ghazaly, M.; Backe, H.; Lauth, W.; Kube, G.; Kunz, P.; Sharafutdinov, A.; Weber, T.

    2006-05-01

    Experiments have been performed to explore the potential of the low emittance 855MeV electron beam of the Mainz Microtron MAMI for imaging with coherent X-rays. Transition radiation from a micro-focused electron beam traversing a foil stack served as X-ray source with good transverse coherence. Refraction contrast radiographs of low absorbing materials, in particular polymer strings with diameters between 30 and 450μm, were taken with a polychromatic transition radiation X-ray source with a spectral distribution in the energy range between 8 and about 40keV. The electron beam spot size had standard deviation σh = (8.6±0.1)μm in the horizontal and σv = (7.5±0.1)μm in the vertical direction. X-ray films were used as detectors. The source-to-detector distance amounted to 11.4m. The objects were placed in a distance of up to 6m from the X-ray film. Holograms of strings were taken with a beam spot size σv = (0.50±0.05)μm in vertical direction, and a monochromatic X-ray beam of 6keV energy. A good longitudinal coherence has been obtained by the (111) reflection of a flat silicon single crystal in Bragg geometry. It has been demonstrated that a direct exposure CCD chip with a pixel size of 13×13μm^2 provides a highly efficient on-line detector. Contrast images can easily be generated with a complete elimination of all parasitic background. The on-line capability allows a minimization of the beam spot size by observing the smallest visible interference fringe spacings or the number of visible fringes. It has been demonstrated that X-ray films are also very useful detectors. The main advantage in comparison with the direct exposure CCD chip is the resolution. For the Structurix D3 (Agfa) X-ray film the standard deviation of the resolution was measured to be σf = (1.2±0.4)μm, which is about a factor of 6 better than for the direct exposure CCD chip. With the small effective X-ray spot size in vertical direction of σv = (1.2±0.3)μm and a geometrical

  13. Compact X-ray source based on Compton backscattering

    CERN Document Server

    Bulyak, E V; Zelinsky, A; Karnaukhov, I; Kononenko, S; Lapshin, V G; Mytsykov, A; Telegin, Yu P; Khodyachikh, A; Shcherbakov, A; Molodkin, V; Nemoshkalenko, V; Shpak, A

    2002-01-01

    The feasibility study of an intense X-ray source based on the interaction between the electron beam in a compact storage ring and the laser pulse accumulated in an optical resonator is carried out. We propose to reconstruct the 160 MeV electron storage ring N-100, which was shutdown several years ago. A new magnetic lattice will provide a transverse of electron beam size of approx 35 mu m at the point of electron beam-laser beam interaction. The proposed facility is to generate X-ray beams of intensity approx 2.6x10 sup 1 sup 4 s sup - sup 1 and spectral brightness approx 10 sup 1 sup 2 phot/0.1%bw/s/mm sup 2 /mrad sup 2 in the energy range from 10 keV up to 0.5 MeV. These X-ray beam parameters meet the requirements for most of technological and scientific applications. Besides, we plan to use the new facility for studying the laser cooling effect.

  14. Compact X-ray source based on Compton backscattering

    Energy Technology Data Exchange (ETDEWEB)

    Bulyak, E.; Gladkikh, P.; Zelinsky, A. E-mail: zelinsky@kipt.kharkov.ua; Karnaukhov, I.; Kononenko, S.; Lapshin, V.; Mytsykov, A.; Telegin, Yu.; Khodyachikh, A.; Shcherbakov, A.; Molodkin, V.; Nemoshkalenko, V.; Shpak, A

    2002-07-21

    The feasibility study of an intense X-ray source based on the interaction between the electron beam in a compact storage ring and the laser pulse accumulated in an optical resonator is carried out. We propose to reconstruct the 160 MeV electron storage ring N-100, which was shutdown several years ago. A new magnetic lattice will provide a transverse of electron beam size of {approx}35 {mu}m at the point of electron beam-laser beam interaction. The proposed facility is to generate X-ray beams of intensity {approx}2.6x10{sup 14} s{sup -1} and spectral brightness {approx}10{sup 12} phot/0.1%bw/s/mm{sup 2}/mrad{sup 2} in the energy range from 10 keV up to 0.5 MeV. These X-ray beam parameters meet the requirements for most of technological and scientific applications. Besides, we plan to use the new facility for studying the laser cooling effect.

  15. The effect of target thickness on x-ray production by FXR [Flash X-Ray Machine

    International Nuclear Information System (INIS)

    Back, N.L.

    1986-01-01

    The electron-photon transport code SANDYL has been used to calculate the x-ray flux for a simplified Flash X-Ray Machine (FXR) bullnose geometry. Four different thicknesses (24.5, 36.75, 49, and 61.25 mils) were used for the tantalum bremsstrahlung target in order to study the effect of target thickness on the FXR output. The calculations were performed for a parallel 17 MeV electron beam, and the resulting angular distributions were then used to compute the forward flux for the more realistic case of a converging beam. Over the range of thicknesses studied, the x-ray energy content per steradian on axis was essentially independent of target thickness. The main reason for this is that, while the total x-ray flux coming out of the target increases with increasing target thickness, the angular width of that flux also increases. The implications for target wheel design are discussed. 3 refs., 7 figs

  16. Automated three-dimensional X-ray analysis using a dual-beam FIB

    International Nuclear Information System (INIS)

    Schaffer, Miroslava; Wagner, Julian; Schaffer, Bernhard; Schmied, Mario; Mulders, Hans

    2007-01-01

    We present a fully automated method for three-dimensional (3D) elemental analysis demonstrated using a ceramic sample of chemistry (Ca)MgTiO x . The specimen is serially sectioned by a focused ion beam (FIB) microscope, and energy-dispersive X-ray spectrometry (EDXS) is used for elemental analysis of each cross-section created. A 3D elemental model is reconstructed from the stack of two-dimensional (2D) data. This work concentrates on issues arising from process automation, the large sample volume of approximately 17x17x10 μm 3 , and the insulating nature of the specimen. A new routine for post-acquisition data correction of different drift effects is demonstrated. Furthermore, it is shown that EDXS data may be erroneous for specimens containing voids, and that back-scattered electron images have to be used to correct for these errors

  17. ADVANCED X-BAND TEST ACCELERATOR FOR HIGH BRIGHTNESS ELECTRON AND GAMMA RAY BEAMS

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, R A; Anderson, S G; Barty, C P; Chu, T S; Ebbers, C A; Gibson, D J; Hartemann, F V; Adolphsen, C; Jongewaard, E N; Raubenheimer, T; Tantawi, S G; Vlieks, A E; Wang, J W

    2010-05-12

    In support of Compton scattering gamma-ray source efforts at LLNL, a multi-bunch test stand is being developed to investigate accelerator optimization for future upgrades. This test stand will enable work to explore the science and technology paths required to boost the current 10 Hz monoenergetic gamma-ray (MEGa-Ray) technology to an effective repetition rate exceeding 1 kHz, potentially increasing the average gamma-ray brightness by two orders of magnitude. Multiple bunches must be of exceedingly high quality to produce narrow-bandwidth gamma-rays. Modeling efforts will be presented, along with plans for a multi-bunch test stand at LLNL. The test stand will consist of a 5.5 cell X-band rf photoinjector, single accelerator section, and beam diagnostics. The photoinjector will be a high gradient standing wave structure, featuring a dual feed racetrack coupler. The accelerator will increase the electron energy so that the emittance can be measured using quadrupole scanning techniques. Multi-bunch diagnostics will be developed so that the beam quality can be measured and compared with theory. Design will be presented with modeling simulations, and layout plans.

  18. Soft x-ray lasers

    International Nuclear Information System (INIS)

    Matthews, D.L.; Rosen, M.D.

    1988-01-01

    One of the elusive dreams of laser physicists has been the development of an x-ray laser. After 25 years of waiting, the x-ray laser has at last entered the scientific scene, although those now in operation are still laboratory prototypes. They produce soft x rays down to about five nanometers. X-ray lasers retain the usual characteristics of their optical counterparts: a very tight beam, spatial and temporal coherence, and extreme brightness. Present x-ray lasers are nearly 100 times brighter that the next most powerful x-ray source in the world: the electron synchrotron. Although Lawrence Livermore National Laboratory (LLNL) is widely known for its hard-x-ray laser program which has potential applications in the Strategic Defense Initiative, the soft x-ray lasers have no direct military applications. These lasers, and the scientific tools that result from their development, may one day have a place in the design and diagnosis of both laser fusion and hard x-ray lasers. The soft x-ray lasers now in operation at the LLNL have shown great promise but are still in the primitive state. Once x-ray lasers become reliable, efficient, and economical, they will have several important applications. Chief among them might be the creation of holograms of microscopic biological structures too small to be investigated with visible light. 5 figs

  19. Measurements and simulations of focused beam for orthovoltage therapy

    International Nuclear Information System (INIS)

    Abbas, Hassan; Mahato, Dip N.; Satti, Jahangir; MacDonald, C. A.

    2014-01-01

    Purpose: Megavoltage photon beams are typically used for therapy because of their skin-sparing effect. However, a focused low-energy x-ray beam would also be skin sparing, and would have a higher dose concentration at the focal spot. Such a beam can be produced with polycapillary optics. MCNP5 was used to model dose profiles for a scanned focused beam, using measured beam parameters. The potential of low energy focused x-ray beams for radiation therapy was assessed. Methods: A polycapillary optic was used to focus the x-ray beam from a tungsten source. The optic was characterized and measurements were performed at 50 kV. PMMA blocks of varying thicknesses were placed between optic and the focal spot to observe any variation in the focusing of the beam after passing through the tissue-equivalent material. The measured energy spectrum was used to model the focused beam in MCNP5. A source card (SDEF) in MCNP5 was used to simulate the converging x-ray beam. Dose calculations were performed inside a breast tissue phantom. Results: The measured focal spot size for the polycapillary optic was 0.2 mm with a depth of field of 5 mm. The measured focal spot remained unchanged through 40 mm of phantom thickness. The calculated depth dose curve inside the breast tissue showed a dose peak several centimeters below the skin with a sharp dose fall off around the focus. The percent dose falls below 10% within 5 mm of the focus. It was shown that rotating the optic during scanning would preserve the skin-sparing effect of the focused beam. Conclusions: Low energy focused x-ray beams could be used to irradiate tumors inside soft tissue within 5 cm of the surface

  20. Synchrotron X-ray micro-beam studies of ancient Egyptian make-up

    Science.gov (United States)

    Martinetto, P.; Anne, M.; Dooryhée, E.; Drakopoulos, M.; Dubus, M.; Salomon, J.; Simionovici, A.; Walter, Ph.

    2001-07-01

    Vases full of make-up are most often present in the burial furniture of Egyptian tombs dated from the pharaonic period. The powdered cosmetics made of isolated grains are analysed to identify their trace element signature. From this signature we identify the provenance of the mineral ingredients in the make-up and we observe different impurities in products, which have been demonstrated as synthetic substances by previous works. Focused X-ray micro-beam ( 2×5 μm2) is successively tuned at 11 keV, below the L III absorption edge of Pb, and 31.8 keV for global characterisation of the metal impurities. The fluorescence signal integrated over each single grain is detected against the X-ray micro-diffraction pattern collected in transmission with a bi-dimensional detector. Furthermore, for galena grains rich in Zn, the XANES signal at the K-absorption edge of Zn shows its immediate nearest-neighbour environment.

  1. Human soft tissue analysis using x-ray or gamma-ray techniques

    International Nuclear Information System (INIS)

    Theodorakou, C; Farquharson, M J

    2008-01-01

    This topical review is intended to describe the x-ray techniques used for human soft tissue analysis. X-ray techniques have been applied to human soft tissue characterization and interesting results have been presented over the last few decades. The motivation behind such studies is to provide improved patient outcome by using the data obtained to better understand a disease process and improve diagnosis. An overview of theoretical background as well as a complete set of references is presented. For each study, a brief summary of the methodology and results is given. The x-ray techniques include x-ray diffraction, x-ray fluorescence, Compton scattering, Compton to coherent scattering ratio and attenuation measurements. The soft tissues that have been classified using x-rays or gamma rays include brain, breast, colon, fat, kidney, liver, lung, muscle, prostate, skin, thyroid and uterus. (topical review)

  2. Characterisation of microfocused beam for synchrotron powder diffraction using a new X-ray camera

    International Nuclear Information System (INIS)

    Thomas, C; Potter, J; Tang, C C; Lennie, A R

    2012-01-01

    The powder diffraction beamline I11, Diamond Light Source, is being continually upgraded as requirements of the user community evolve. Intensities of X-rays from the I11 in-vacuum electron undulator in the 3 GeV synchrotron fall off at higher energies. By focusing higher energy X-rays, we can overcome flux limitations, and open up new diffraction experiments. Here, we describe characterisation of microfocusing using compound refractive lenses (CRL). For a relatively modest outlay, we have developed an experimental setup and a novel X-ray camera with good sensitivity and a resolution specification suitable for characterising these focusing optics. We show that vertical oscillations in the focused beam compromise resolution of the source imaged by the CRL. Nevertheless, we have measured CRL focusing properties, and demonstrate the use of energy scanning to determine lens alignment. Real benefits of the intensity gain are illustrated.

  3. Precise material identification method based on a photon counting technique with correction of the beam hardening effect in X-ray spectra

    International Nuclear Information System (INIS)

    Kimoto, Natsumi; Hayashi, Hiroaki; Asahara, Takashi; Mihara, Yoshiki; Kanazawa, Yuki; Yamakawa, Tsutomu; Yamamoto, Shuichiro; Yamasaki, Masashi; Okada, Masahiro

    2017-01-01

    The aim of our study is to develop a novel material identification method based on a photon counting technique, in which the incident and penetrating X-ray spectra are analyzed. Dividing a 40 kV X-ray spectra into two energy regions, the corresponding linear attenuation coefficients are derived. We can identify the materials precisely using the relationship between atomic number and linear attenuation coefficient through the correction of the beam hardening effect of the X-ray spectra. - Highlights: • We propose a precise material identification method to be used as a photon counting system. • Beam hardening correction is important, even when the analysis is applied to the short energy regions in the X-ray spectrum. • Experiments using a single probe-type CdTe detector were performed, and Monte Carlo simulation was also carried out. • We described the applicability of our method for clinical diagnostic X-ray imaging in the near future.

  4. X-ray backscatter imaging with a spiral scanner

    International Nuclear Information System (INIS)

    Bossi, R.H.; Cline, J.L.; Friddell, K.D.

    1989-01-01

    X-ray backscatter imaging allows radiographic inspections to be performed with access to only one side of the object. A collimated beam of radiation striking an object will scatter x-rays by Compton scatter and x-ray fluorescence. A detector located on the source side of the part will measure the backscatter signal. By plotting signal strength as gray scale intensity vs. beam position on the object, an image of the object can be constructed. A novel approach to the motion of the collimated incident beam is a spiral scanner. The spiral scanner approach, described in this paper, can image an area of an object without the synchronized motion of the object or detector, required by other backscatter imaging techniques. X-ray backscatter is particularly useful for flaw detection in light element materials such as composites. The ease of operation and the ability to operate non-contact from one side of an object make x-ray backscatter imaging of increasing interest to industrial inspection problems

  5. X-ray spectroscopy of highly-ionized atoms in an electron beam ion trap (EBIT)

    International Nuclear Information System (INIS)

    Marrs, R.E.; Bennett, C.; Chen, M.H.

    1988-01-01

    An Electron Beam Ion Trap at Lawrence Livermore National Laboratory is being used to produce and trap very-highly-charged-ions (q /le/ 70+) for x-ray spectroscopy measurements. Recent measurements of dielectronic recombination, electron impact excitation and transition energies are presented. 15 refs., 12 figs., 1 tab

  6. Optimization of breast cancer detection in Dual Energy X-ray Mammography using a CMOS imaging detector

    International Nuclear Information System (INIS)

    Koukou, V; Martini, N; Sotiropoulou, P; Nikiforidis, G; Fountos, G; Michail, C; Kalyvas, N; Valais, I; Kandarakis, I; Bakas, A; Kounadi, E

    2015-01-01

    Dual energy mammography has the ability to improve the detection of microcalcifications leading to early diagnosis of breast cancer. In this simulation study, a prototype dual energy mammography system, using a CMOS based imaging detector with different X-ray spectra, was modeled. The device consists of a 33.91 mg/cm 2 Gd 2 O 2 S:Tb scintillator screen, placed in direct contact with the sensor, with a pixel size of 22.5 μm. Various filter materials and tube voltages of a Tungsten (W) anode for both the low and high energy were examined. The selection of the filters applied to W spectra was based on their K- edges (K-edge filtering). Hydroxyapatite (HAp) was used to simulate microcalcifications. Calcification signal-to-noise ratio (SNR tc ) was calculated for entrance surface dose within the acceptable levels of conventional mammography. Optimization was based on the maximization of SNR tc while minimizing the entrance dose. The best compromise between SNR tc value and dose was provided by a 35kVp X-ray spectrum with added beam filtration of 100μm Pd and a 70kVp Yb filtered spectrum of 800 μm for the low and high energy, respectively. Computer simulation results show that a SNR tc value of 3.6 can be achieved for a calcification size of 200 μm. Compared with previous studies, this method can improve detectability of microcalcifications

  7. Optical and mechanical design of the extended x-ray absorption fine structure (EXAFS) beam-line at Indus-II synchrotron source

    International Nuclear Information System (INIS)

    Das, N.C.; Jha, S.N.; Bhattacharyya, D.; Sinha, A.K.; Mishra, V.K.; Verma, Vishnu; Ghosh, A.K.

    2002-11-01

    An extended x-ray absorption fine structure (EXAFS) beam line for x-ray absorption studies using energy dispersive geometry and position sensitive detector is being designed for the INDUS-II Synchrotron source. The beam line would be used for doing x-ray absorption experiments involving measurements of fme structures above the absorption edge of different species of atoms in a material The results of the above experiments would lead to the determination of different important structural parameters of materials viz.. inter-atomic distance. co-ordination number, degree of disorder and radial distribution function etc. The optical design of the beam line has been completed based on the working principle that a single crystal bent in the shape of an ellipse by a crystal bender would act as a dispersing as well as focusing element. The mechanical design of the beam line including the crystal bender has also been completed and discussed here. Calculations have been done to detennine the temperature profile on the different components of the beam line under exposure to synchrotron radiation and proper cooling channels have been designed to bring down the heat load on the components. (author)

  8. Gamma-ray detectors for breast imaging

    Science.gov (United States)

    Williams, Mark B.; Goode, Allen R.; Majewski, Stan; Steinbach, Daniela; Weisenberger, Andrew G.; Wojcik, Randolph F.; Farzanpay, Farzin

    1997-07-01

    Breast cancer is the most common cancer of American women and is the leading cause of cancer-related death among women aged 15 - 54; however recent years have shown that early detection using x-ray mammography can lead to a high probability of cure. However, because of mammography's low positive predictive value, surgical or core biopsy is typically required for diagnosis. In addition, the low radiographic contrast of many nonpalpable breast masses, particularly among women with radiographically dense breasts, results in an overall rate of 10% to 25% for missed tumors. Nuclear imaging of the breast using single gamma emitters (scintimammography) such as (superscript 99m)Tc, or positron emitters such as F-18- fluorodeoxyglucose (FDG) for positron emission tomography (PET), can provide information on functional or metabolic tumor activity that is complementary to the structural information of x-ray mammography, thereby potentially reducing the number of unnecessary biopsies and missed cancers. This paper summarizes recent data on the efficacy of scintimammography using conventional gamma cameras, and describes the development of dedicated detectors for gamma emission breast imaging. The detectors use new, high density crystal scintillators and large area position sensitive photomultiplier tubes (PSPMTs). Detector design, imaging requirements, and preliminary measured imaging performance are discussed.

  9. Monte Carlo simulation of x-ray buildup factors of lead and its applications in shielding of diagnostic x-ray facilities

    International Nuclear Information System (INIS)

    Kharrati, Hedi; Agrebi, Amel; Karaoui, Mohamed-Karim

    2007-01-01

    X-ray buildup factors of lead in broad beam geometry for energies from 15 to 150 keV are determined using the general purpose Monte Carlo N-particle radiation transport computer code (MCNP4C). The obtained buildup factors data are fitted to a modified three parameter Archer et al. model for ease in calculating the broad beam transmission with computer at any tube potentials/filters combinations in diagnostic energies range. An example for their use to compute the broad beam transmission at 70, 100, 120, and 140 kVp is given. The calculated broad beam transmission is compared to data derived from literature, presenting good agreement. Therefore, the combination of the buildup factors data as determined and a mathematical model to generate x-ray spectra provide a computationally based solution to broad beam transmission for lead barriers in shielding x-ray facilities

  10. Optimizing contrast agents with respect to reducing beam hardening in nonmedical X-ray computed tomography experiments.

    Science.gov (United States)

    Nakashima, Yoshito; Nakano, Tsukasa

    2014-01-01

    Iodine is commonly used as a contrast agent in nonmedical science and engineering, for example, to visualize Darcy flow in porous geological media using X-ray computed tomography (CT). Undesirable beam hardening artifacts occur when a polychromatic X-ray source is used, which makes the quantitative analysis of CT images difficult. To optimize the chemistry of a contrast agent in terms of the beam hardening reduction, we performed computer simulations and generated synthetic CT images of a homogeneous cylindrical sand-pack (diameter, 28 or 56 mm; porosity, 39 vol.% saturated with aqueous suspensions of heavy elements assuming the use of a polychromatic medical CT scanner. The degree of cupping derived from the beam hardening was assessed using the reconstructed CT images to find the chemistry of the suspension that induced the least cupping. The results showed that (i) the degree of cupping depended on the position of the K absorption edge of the heavy element relative to peak of the polychromatic incident X-ray spectrum, (ii) (53)I was not an ideal contrast agent because it causes marked cupping, and (iii) a single element much heavier than (53)I ((64)Gd to (79)Au) reduced the cupping artifact significantly, and a four-heavy-element mixture of elements from (64)Gd to (79)Au reduced the artifact most significantly.

  11. Supershort avalanche electron beams and x-ray in high-pressure nanosecond discharges

    International Nuclear Information System (INIS)

    Tarasenko, V F; Baksht, E H; Kostyrya, I D; Lomaev, M I; Rybka, D V

    2008-01-01

    The properties of a supershort avalanche electron beam (S AEB) and X-ray radiation produced using a nanosecond volume discharge are examined. An electron beam of the runaway electrons with amplitude of ∼ 50 A has been obtained in air atmospheric pressure. It is reported that S AEB is formed in the angle above 2π sr. Three groups of the runaway electrons are formed in a gas diode under atmospheric air pressure, when nanosecond voltage pulses with amplitude of hundreds of kilovolts are applied. The electron beam has been generated behind a 45 μm thick AlBe foil in SF 6 and Xe under the pressure of 2 arm, and in He under the pressure of about 12 atm. The paper gives the analysis of a generation mechanism of SAEB.

  12. A multiple CCD X-ray detector and its first operation with synchrotron radiation X-ray beam

    CERN Document Server

    Suzuki, M; Kumasaka, T; Sato, K; Toyokawa, H; Aries, I F; Jerram, P A; Ueki, T

    1999-01-01

    A 4x4 array structure of 16 identical CCD X-ray detector modules, called the multiple CCD X-ray detector system (MCCDX), was submitted to its first synchrotron radiation experiment at the protein crystallography station of the RIKEN beamline (BL45XU) at the SPring-8 facility. An X-ray diffraction pattern of cholesterol powder was specifically taken in order to investigate the overall system performance.

  13. X-ray spectroscopy with EBIT

    International Nuclear Information System (INIS)

    Beiersdorfer, P.; Cauble, R.; Chen, M.; DelGrande, N.; Knapp, D.; Marrs, R.; Osterheld, A.; Reed, K.; Schneider, M.; Scofield, J.; Wong, K.; Vogel, D.; Zasadzinski, R.; Chantrenne, S.; Wargelin, B.

    1992-04-01

    X-ray spectroscopy with the Livermore electron beam ion traps provides data on a wide range of atomic physics issues including ionization, recombination, and excitation cross sections, identification of forbidden transitions, and contributions from relatively and quantum electrodynamics to the transition energies. Here we briefly discuss the source characteristics and x-ray instrumentation, and report measurements of the excitation cross sections of the Kα transitions in heliumlike Ti 20+ as a function of beam energy. The measurements allow detailed comparisons with theoretical predictions of the direct electron-impact excitation cross sections, resonance-excitation contributions, and the electron temperature dependence of the ratio of triplet and singlet lines. The results demonstrate the importance of such measurements for increasing the reliability of x-ray diagnostics of laboratory and astrophysical plasmas

  14. SU-G-201-08: Energy Response of Thermoluminescent Microcube Dosimeters in Water for Kilovoltage X-Ray Beams

    Energy Technology Data Exchange (ETDEWEB)

    Di Maso, L; Lawless, M; Culberson, W; DeWerd, L [University of Wisconsin- Madison, Madison, WI (United States)

    2016-06-15

    Purpose: To characterize the energy dependence for TLD-100 microcubes in water at kilovoltage energies. Methods: TLD-100 microcubes with dimensions of (1 × 1 × 1) mm{sup 3} were irradiated with kilovoltage x-rays in a custom-built thin-window liquid water phantom. The TLD-100 microcubes were held in Virtual Water™ probes and aligned at a 2 cm depth in water. Irradiations were performed using the M-series x-ray beams of energies ranging from 50-250 kVp and normalized to a {sup 60}Co beam located at the UWADCL. Simulations using the EGSnrc Monte Carlo Code System were performed to model the x-ray beams, the {sup 60}Co beam, the water phantom and the dosimeters in the phantom. The egs-chamber user code was used to tally the dose to the TLDs and the dose to water. The measurements and calculations were used to determine the intrinsic energy dependence, absorbed-dose energy dependence, and absorbed-dose sensitivity. These values were compared to TLD-100 chips with dimensions of (3.2 × 0.9 × 0.9) mm{sup 3}. Results: The measured TLD-100 microcube response per dose to water among all investigated x-ray energies had a maximum percent difference of 61% relative to {sup 60}Co. The simulated ratio of dose to water to the dose to TLD had a maximum percent difference of 29% relative to {sup 60}Co. The ratio of dose to TLD to the TLD output had a maximum percent difference of 13% relative to {sup 60}Co. The maximum percent difference for the absorbed-dose sensitivity was 15% more than the used value of 1.41. Conclusion: These results confirm that differences in beam quality have a significant effect on TLD response when irradiated in water. These results also indicated a difference in TLD-100 response between microcube and chip geometries. The intrinsic energy dependence and the absorbed-dose energy dependence deviated up to 10% between TLD-100 microcubes and chips.

  15. Sterilization of Bacillus spores by converted X-rays

    International Nuclear Information System (INIS)

    Ito, Hitoshi; Ohki, Yumi; Watanabe, Yuhei; Sunaga, Hiromi; Ishigaki, Isao

    1991-01-01

    Relative sensitivities of endospores of Bacillus pumilus E601, B. subtilis IAM1069, B. megaterium S31 and B. brevis S5 to gamma-rays, converted X-rays (Bremsstrahlung), and electron beams were examined in order to estimate the conditions in which converted X-rays kill Bacillus spores. The radiation sensitivities to gamma-rays, X-rays and electron beams of each strain dried on glass fiber filter without additives were found to be almost equivalent, and D 10 values were obtained as follows: 1.5-1.6 kGy for B. pumilus, 1.4-1.5 kGy for B. subtilis, 1.9-2.0 kGy for B. megaterium, and 1.6-2.0 kGy for B. brevis. The radiation sensitivities of endospores of each strain to electron beams were slightly lower than those to gamma-rays in the dry condition with additives of 2% peptone + 1% glycerin on glass fiber filter. The increase of radiation resistance in the presence of additives was also observed with X-rays, and it was on an intermediate level between those with gamma-rays and electron beams. In the dry condition using cellulose filter paper, only the radiation resistances of B. megaterium and B. brevis in the presence of additives were increased. (author)

  16. U-shape rotating anti-cathode compact X-ray generator: 20 times stronger than the commercially available X-ray source

    Energy Technology Data Exchange (ETDEWEB)

    Sakabe, N., E-mail: sakabe-dsb@sbsp.jp; Sakabe, K. [High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba 305-0801 (Japan); Foundation for Advancement of International Science (FAIS), Kasuga 3-chome, Tsukuba, Ibaraki 305-0821 (Japan); Ohsawa, S.; Sakai, T.; Kobayakawa, H.; Sugimura, T.; Ikeda, M.; Tawada, M. [High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Watanabe, N.; Sasaki, K. [Nagoya University, Chikusa, Nagoya, Aichi 464-8603 (Japan); Wakatsuki, M. [National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8568 (Japan)

    2013-11-01

    A new type of U-shape anti-cathode X-ray generator in which the inner surface of a cylindrical target is irradiated by an electron beam has been made by modifying a conventional rotating anti-cathode X-ray generator whose brightness in the catalog is 12 kW mm{sup −2}. A brightness of 129 kW mm{sup −2} was thereby obtained with this new U-shape-type X-ray generator. This new X-ray generator is expected to be of keen interest for applications in academia, industry and in hospitals. A new type of U-shape anti-cathode X-ray generator in which the inner surface of a cylindrical target is irradiated by an electron beam has been made by modifying a conventional rotating anti-cathode X-ray generator whose brightness in the catalog is 12 kW mm{sup −2}. The target material (Cu), target radius (50 mm) and rotating speed (6000 r.p.m.) were not changed in this modification. A brightness of 52 kW mm{sup −2} was obtained by this U-shape-type X-ray generator. This means that the brightness of the new type is 4.3 times greater than that of the old unmodified one. Furthermore, the new-type X-ray generator yielded a brightness of 129 kW mm{sup −2} by adding a carbon coating on the Cu target. This means an overall increase of brightness of ten times. The original generator has the highest brightness in the generators of the same class (having a radius of 50 mm and rotation speed of 6000 r.p.m.). Observations showed that Cu Kα counts at vertical incidence of the electron beam onto the surface of the new target, which is initially optically smooth, decrease as the surface is roughened by a severe thermal stress caused by strong electron beam exposure. Further observation reveals, however, that oblique incidence of the electron beam onto the roughened surface drastically increased the X-ray output and amounts to twice as much as that from a smooth surface at vertical incidence. Thus, at the present stage, an overall increase of brightness has been realised at a level 20 times

  17. X-ray backscatter radiography. Intrusive instead of penetrating, X-ray shadow phenomenon

    International Nuclear Information System (INIS)

    Wrobel, Norma; Kolkoori, Sanjeevareddy; Osterloh, Kurt; European Federation for Non-Destructive Testing

    2013-01-01

    Generally, the primary practical advantage of X-ray backscattering radiography is that there is no need to place a detector on the side of the specimen opposite to the source. Such a situation usually is encountered whenever the specimen is not only standing right in front of a wall or even inside a wall but also if the specimen is such big that radiography is not possible because of the layer thickness to be penetrated. The method used here differs fundamentally from the conventional method to interrogate the object with a scanning beam ('pencil beam') and to collect the whole backscattered radiation from the area. The object is fully illuminated by a (uncollimated) cone beam. Here, the image is recorded with a camera of absorbent material (tungsten, lead), which contains a matrix detector as the image receiver. The optical effect is generated by a special twisted slit collimator which operates according to an extended pinhole camera. The independent positioning of source and camera allows a variable irradiation geometry which causes different images as a result. As a consequence, a complex object in front of a backscattering wall appears completely different than standing alone. So X-ray backscatter images have to be interpreted according to their illumination with X-rays and their surroundings. (orig.)

  18. Modelling properties of hard x-rays generated by the interaction between relativistic electrons and very intense laser beams

    International Nuclear Information System (INIS)

    Popa, Alexandru

    2009-01-01

    In a previous paper we presented a calculation model for high harmonic generation by relativistic Thomson scattering of the electromagnetic radiation by free electrons. In this paper we present a similar model for the calculation of the energies of hard x-rays (20- 200 keV) resulted from the interaction between relativistic electrons (20-100 MeV) and very intense laser beams. Starting from the relativistic equations of motion of an electron in the electromagnetic field we show that the Lienard-Wiechert equation leads to electromagnetic waves whose frequencies are in the domain of hard x-rays. When the relativistic parameter of the laser beam is greater than unity, the model predicts the existence of harmonics of the above frequencies. Our theoretical values are in good agreement with experimental values of the x-ray energies from the literature and predict accurately their angular distribution.

  19. Flat Field Anomalies in an X-ray CCD Camera Measured Using a Manson X-ray Source (HTPD 08 paper)

    International Nuclear Information System (INIS)

    Haugh, M; Schneider, M B

    2008-01-01

    The Static X-ray Imager (SXI) is a diagnostic used at the National Ignition Facility (NIF) to measure the position of the X-rays produced by lasers hitting a gold foil target. The intensity distribution taken by the SXI camera during a NIF shot is used to determine how accurately NIF can aim laser beams. This is critical to proper NIF operation. Imagers are located at the top and the bottom of the NIF target chamber. The CCD chip is an X-ray sensitive silicon sensor, with a large format array (2k x 2k), 24 (micro)m square pixels, and 15 (micro)m thick. A multi-anode Manson X-ray source, operating up to 10kV and 10W, was used to characterize and calibrate the imagers. The output beam is heavily filtered to narrow the spectral beam width, giving a typical resolution E/ΔE ∼ 10. The X-ray beam intensity was measured using an absolute photodiode that has accuracy better than 1% up to the Si K edge and better than 5% at higher energies. The X-ray beam provides full CCD illumination and is flat, within ±1% maximum to minimum. The spectral efficiency was measured at 10 energy bands ranging from 930 eV to 8470 eV. We observed an energy dependent pixel sensitivity variation that showed continuous change over a large portion of the CCD. The maximum sensitivity variation occurred at 8470 eV. The geometric pattern did not change at lower energies, but the maximum contrast decreased and was not observable below 4 keV. We were also able to observe debris, damage, and surface defects on the CCD chip. The Manson source is a powerful tool for characterizing the imaging errors of an X-ray CCD imager. These errors are quite different from those found in a visible CCD imager

  20. X-ray examination equipment for heart diagnostics

    International Nuclear Information System (INIS)

    Kok, P.W.

    1979-01-01

    For heart catheterization the X-ray tube and the image intensifier can be shifted parallel to the scanning plane. Without moving the patient it is also possible to displace the system X-ray tube/image intensifier arbitrarily in space, while keeping up the direction of the X-ray beam. (RW) [de

  1. A simulation-based study on the influence of beam hardening in X-ray computed tomography for dimensional metrology.

    Science.gov (United States)

    Lifton, Joseph J; Malcolm, Andrew A; McBride, John W

    2015-01-01

    X-ray computed tomography (CT) is a radiographic scanning technique for visualising cross-sectional images of an object non-destructively. From these cross-sectional images it is possible to evaluate internal dimensional features of a workpiece which may otherwise be inaccessible to tactile and optical instruments. Beam hardening is a physical process that degrades the quality of CT images and has previously been suggested to influence dimensional measurements. Using a validated simulation tool, the influence of spectrum pre-filtration and beam hardening correction are evaluated for internal and external dimensional measurements. Beam hardening is shown to influence internal and external dimensions in opposition, and to have a greater influence on outer dimensions compared to inner dimensions. The results suggest the combination of spectrum pre-filtration and a local gradient-based surface determination method are able to greatly reduce the influence of beam hardening in X-ray CT for dimensional metrology.

  2. Exploring vacuum birefringence based on a 100 PW laser and an x-ray free electron laser beam

    Science.gov (United States)

    Shen, Baifei; Bu, Zhigang; Xu, Jiancai; Xu, Tongjun; Ji, Liangliang; Li, Ruxin; Xu, Zhizhan

    2018-04-01

    Exploring vacuum birefringence with the station of extreme light at Shanghai Coherent Light Facility is considered. Laser pulses of intensity beyond 1023 W cm-2 are capable of polarizing the vacuum due to the ultra-strong electro-magnetic fields. The subtle difference of the vacuum refractive indexes along electric and magnetic fields leads to a birefringence effect for lights propagating through. The vacuum birefringence effect can now be captured by colliding a hard x-ray free electron laser (XFEL) beam with a high-power laser. The initial XFEL beam of pure linear polarization is predicated to gain a very small ellipticity after passing through the laser stimulated vacuum. Various interaction geometries are considered, showing that the estimated ellipticity lies between 1.8 × 10-10 and 10-9 for a 100 PW laser interacting with a 12.9 keV XFEL beam, approaching the threshold for todays’ polarity detection technique. The detailed experimental set-up is designed, including the polarimeter, the focusing compound refractive lens and the optical path. When taking into account the efficiencies of the x-ray instruments, it is found that about 10 polarization-flipped x-ray photons can be detected for a single shot for our design. Considering the background noise level, accumulating runs are necessary to obtain high confident measurement.

  3. Tc-99m Methoxy Isobutyl Isonitrile (MIBI) scintimammography for detection of loco-regional recurrence of breast cancer: A comparative study of scintimammography, X-ray mammography and breast ultrasound imaging

    International Nuclear Information System (INIS)

    Usmani, S.; Niaz, K.; Ahmed, N.; Niyaz, K.; Khan, H.A.; Javed, A.; Mohannadi, S.A.; Huda, F.A.

    2007-01-01

    Breast cancer is the most common cancer among women and the second leading cause of death in women after lung cancer. Local recurrence rate is about 1-2% per year. It is important to find a sensitive and accurate diagnostic method for early detection of recurrent tumor for planning subsequent management. The principal aim of the present study was to assess the utility of Tc-99m MIBI scintimammography in the detection of loco-regional recurrence of breast cancer in comparison with the conventionally used methods like x-ray mammography and ultrasonography. A total number of 42 patients (Age: mean= 45.55 yrs; median = 43.5; range, 22-77 yrs) suspected to have loco-regional recurrence of breast cancer on the basis of clinical examination and/or conventional imaging procedures were included in this study. All patients were subjected to planar scintimammography (SMM), SPECT imaging of the breast, x-ray mammography and Ultrasound scanning. The results were correlated with the final diagnosis arrived at by fine needle aspiration cytology (FNAC), core biopsy or definite wide local excision. Sensitivity (SEN), specificity (SPE), positive predictive value (PPV), negative predictive value (NPV) and accuracy (ACC) of scintimammography in the diagnosis of recurrent disease were found to be 82.75, 92.3, 96.0, 70.58 and 85.71% respectively; compared to 45.83, 66.6, 78.57, 31.57, 51.51 for x-ray mammography and 65.51, 69.23, 82.6, 47.36, 66.66 for Ultrasonography. Scintimammography results were correlated with x-ray mammography and ultrasonography by applying Pearson correlation. No significant correlation was found between SMM and XMM (r=0.27) or SMM and US (r=0.23). Based on the results of this study it is concluded that SMM has better diagnostic accuracy than mammography and ultrasonography in the detection of loco-regional recurrence of breast cancer. (author)

  4. Development, Beam characterization and chromosomal effectiveness of X-rays of RBC characteristic X-ray generator

    International Nuclear Information System (INIS)

    Endo, Satoru; Hoshi, Masaharu; Takada, Jun; Takatsuji, Toshihiro; Ejima, Yosuke; Saigusa, Shin; Tachibana, Akira; Sasaki, Masao S.

    2006-01-01

    A characteristic hot-filament type X-ray generator was constructed for irradiation of cultured cells. The source provides copper K, iron K, chromium K, molybdenum L, aluminium K and carbon K shell characteristic X-rays. When cultured mouse m5S cells were irradiated and frequencies of dicentrics were fitted to a linear-quadratic model, Y=αD+βD 2 , the chromosomal effectiveness was not a simple function of photon energy. The α-terms increased with the decrease of the photon energy and then decreased with further decrease of the energy with an inflection point at around 10 keV. The β-terms stayed constant for the photon energy down to 10 keV and then increased with further decrease of energy. Below 10 keV, the relative biological effectiveness (RBE) at low doses was proportional to the photon energy, which contrasted to that for high energy X- or γ-rays where the RBE was inversely related with the photon energy. The reversion of the energy dependency occurred at around 1-2 Gy, where the RBE of soft X-rays was insensitive to X-ray energy. The reversion of energy-RBE relation at a moderate dose may shed light on the controversy on energy dependency of RBE of ultrasoft X-rays in cell survival experiments. (author)

  5. Bremsstrahlung X rays from Jovian auroral electrons

    International Nuclear Information System (INIS)

    Barbosa, D.D.

    1990-01-01

    The spectrum of X rays from the planet Jupiter is calculated according to an auroral electron beam model. The electrons are assumed to be accelerated by a field-aligned potential drop and penetrate into the atmosphere as a Maxwellian beam of primaries which are scattered, degraded in energy, and merged with a population of ionization secondaries having a power law energy distribution. The soft X rays observed by the Einstein Observatory satelltie are due to bremsstrahlung from the sedondary electrons in the H 2 atmosphere. A good match to the X ray data is obtained if the power law spectral index of the secondary electrons, γ e , is ≅ 2, yielding a power law slope for the photon flux γ X = γ e + 1 ≅ 3. The X ray intensity is best reconciled with a beam of primaries having a characteristic energy 30-100 keV and penetrating the homopause with an auroral energy flux typically of 10-20 ergs cm -2 s -1 but no greater than 50 ergs cm -2 s -1

  6. A free-electron laser fourth-generation X-ray source

    International Nuclear Information System (INIS)

    Moncton, D. E.

    1999-01-01

    The field of synchrotrons radiation research has grown rapidly over the last 25 years due to both the push of the accelerator and magnet technology that produces the x-ray beams and the pull of the extraordinary scientific research those beams make possible. Three successive generations of synchrotrons radiation facilities have resulted in beam brilliances 11 to 12 orders of magnitude greater than the standard laboratory x-ray tube. However, greater advances can be easily imagined given the fact that x-ray beams from present-day facilities do not exhibit the coherence or time structure so familiar with the.optical laser. Theoretical work over the last ten years or so has pointed to the possibility of generating hard x-ray beams with laser-like characteristics. The concept is based on self-amplified spontaneous emission in free electron lasers. The use of a superconducting linac could produce a major, cost-effective facility that spans wavelengths from the ultraviolet to the hard x-ray regime, simultaneously servicing large numbers experimenters from a wide range of disciplines. As with each past generation of synchrotron facilities, immense new scientific opportunities from fourth-generation sources

  7. The toroidicity-induced Alfven eigenmode structure in DIII-D: Implications of soft x-ray and beam-ion loss data

    International Nuclear Information System (INIS)

    Carolipio, E. M.; Heidbrink, W. W.; Cheng, C. Z.; Chu, M. S.; Fu, G. Y.; Jaun, A.; Spong, D. A.; Turnbull, A. D.; White, R. B.

    2001-01-01

    The internal structure of the toroidicity-induced Alfven eigenmode (TAE) is studied by comparing soft x-ray profile and beam ion loss data taken during TAE activity in the DIII-D tokamak [W. W. Heidbrink , Nucl. Fusion 37, 1411 (1997)] with predictions from theories based on ideal magnetohydrodynamic (MHD), gyrofluid, and gyrokinetic models. The soft x-ray measurements indicate a centrally peaked eigenfunction, a feature which is closest to the gyrokinetic model's prediction. The beam ion losses are simulated using a guiding center code. In the simulations, the TAE eigenfunction calculated using the ideal MHD model acts as a perturbation to the equilibrium field. The predicted beam ion losses are an order of magnitude less than the observed ∼6%--8% losses at the peak experimental amplitude of {delta}B r /B 0 ≅2--5 x 10 -4

  8. Moving-Article X-Ray Imaging System and Method for 3-D Image Generation

    Science.gov (United States)

    Fernandez, Kenneth R. (Inventor)

    2012-01-01

    An x-ray imaging system and method for a moving article are provided for an article moved along a linear direction of travel while the article is exposed to non-overlapping x-ray beams. A plurality of parallel linear sensor arrays are disposed in the x-ray beams after they pass through the article. More specifically, a first half of the plurality are disposed in a first of the x-ray beams while a second half of the plurality are disposed in a second of the x-ray beams. Each of the parallel linear sensor arrays is oriented perpendicular to the linear direction of travel. Each of the parallel linear sensor arrays in the first half is matched to a corresponding one of the parallel linear sensor arrays in the second half in terms of an angular position in the first of the x-ray beams and the second of the x-ray beams, respectively.

  9. Spot size characterization of focused non-Gaussian X-ray laser beams

    Czech Academy of Sciences Publication Activity Database

    Chalupský, Jaromír; Krzywinski, J.; Juha, Libor; Hájková, Věra; Cihelka, Jaroslav; Burian, Tomáš; Vyšín, Luděk; Gaudin, J.; Gleeson, A.; Jurek, M.; Khorsand, A.R.; Klinger, D.; Wabnitz, H.; Sobierajski, R.; Störmer, M.; Tiedtke, K.; Toleikis, S.

    2010-01-01

    Roč. 18, č. 26 (2010), s. 27836-27845 ISSN 1094-4087 R&D Projects: GA AV ČR KAN300100702; GA MŠk LC510; GA MŠk(CZ) LC528; GA ČR GAP208/10/2302; GA MŠk LA08024; GA AV ČR IAAX00100903; GA MŠk(CZ) ME10046 Institutional research plan: CEZ:AV0Z10100523 Keywords : X-ray laser * free-electron laser * beam characterization * ablation Subject RIV: BH - Optics, Masers, Lasers Impact factor: 3.749, year: 2010

  10. Higher coherent x-ray laser

    International Nuclear Information System (INIS)

    Hasegawa, Noboru; Nagashima, Keisuke; Kawachi, Tetsuya

    2001-01-01

    X-ray lasers generated by an ultra short pulse laser have advantages such as monochromatic, short pulse duration, small beam divergence, high intensity, and coherence. Spatial coherence is most important for applications, we have investigated the transient collisional excitation (TCE) scheme x-ray laser lasing from Ne-like titanium (31.6 nm), Ne-like silver (13.9 nm) and tin (11.9 nm). However, the spatial coherence was not so good with this scheme. We have been studying to improve the spatial coherence of the x-ray laser and have proposed to use coherent seed light tuned to the x-ray laser wavelength generated from higher harmonics generation (HHG), which is introduced to the x-ray laser medium (Ne-like titanium, Ni-like silver plasmas). We present about the theoretical study of the coupling efficiency HHG light with x-ray laser medium. (author)

  11. X-ray microscopy using collimated and focussed synchrotron radiation

    International Nuclear Information System (INIS)

    Jones, K.W.; Kwiatek, W.M.; Gordon, B.M.

    1987-01-01

    X-ray microscopy is a field that has developed rapidly in recent years. Two different approaches have been used. Zone plates have been employed to produce focused beams with sizes as low as 0.07 μm for x-ray energies below 1 keV. Images of biological materials and elemental maps for major and minor low Z have been produced using above and below absorption edge differences. At higher energies collimators and focusing mirrors have been used to make small diameter beams for excitation of characteristic K- or L-x rays of all elements in the periodic table. The practicality of a single instrument combining all the features of these two approaches is unclear. The use of high-energy x rays for x-ray microscopy has intrinsic value for characterization of thick samples and determination of trace amounts of most elements. A summary of work done on the X-26 beam line at the National Synchrotron Light Source (NSLS) with collimated and focused x rays with energies above 4 keV is given here. 6 refs., 5 figs., 1 tab

  12. Transmission of broad W/Rh and W/Al (target/filter) x-ray beams operated at 25-49 kVp through common shielding materials.

    Science.gov (United States)

    Li, Xinhua; Zhang, Da; Liu, Bob

    2012-07-01

    To provide transmission data for broad 25-39 kVp (kilovolt peak) W/Rh and 25-49 kVp W/Al (target/filter, W-tungsten, Rh-rhodium, and Al-aluminum) x-ray beams through common shielding materials, such as lead, concrete, gypsum wallboard, wood, steel, and plate glass. The unfiltered W-target x-ray spectra measured on a Selenia Dimensions system (Hologic Inc., Bedford, MA) set at 20-49 kVp were, respectively, filtered using 50-μm Rh and 700-μm Al, and were subsequently used for Monte Carlo calculations. The transmission of broad x-ray beams through shielding materials was simulated using Geant4 low energy electromagnetic physics package with photon- and electron-processes above 250 eV, including photoelectric effect, Compton scattering, and Rayleigh scattering. The calculated transmission data were fitted using Archer equation with a robust fitting algorithm. The transmission of broad x-ray beams through the above-mentioned shielding materials was calculated down to about 10(-5) for 25-39 kVp W/Rh and 25-49 kVp W/Al. The fitted results of α, β, and γ in Archer equation were provided. The α values of kVp ≥ 40 were approximately consistent with those of NCRP Report No. 147. These data provide inputs for the shielding designs of x-ray imaging facilities with W-anode x-ray beams, such as from Selenia Dimensions.

  13. Technique charts for Kodak EC-L film screen system for portal localization in a 6MV X-ray beam.

    Science.gov (United States)

    Sandilos, P; Antypas, C; Paraskevopoulou, C; Kouvaris, J; Vlachos, L

    2006-01-01

    Port films are used in radiotherapy for visual evaluation of the radiation fields and subsequent quantitative analysis. Common port films suffer from poor image quality compared to the simulator-diagnostic films and is desirable to determine the appropriate exposure required for the best image contrast. The aim of this work is to generate technique charts for the Kodak EC-L film screen system for use in a 6MV x-ray beam. Three homogeneous water phantoms were used to simulate head-neck, thorax and abdomen dimensions of adult human, correspondingly. The film screen system was calibrated in a 6MV x-ray beam and under various irradiation conditions. The film screen system behavior was studied as a function of phantom thickness, field size and air gap between the phantom and the film screen system. In each case the optimum film exposure which produces the maximum image contrast was determined. The generated technique charts for the EC-L film screen system and for a 6 MV x-ray beam are used in our radiotherapy department for daily quality assurance of the radiotherapy procedure.

  14. Multiple station beamline at an undulator x-ray source

    DEFF Research Database (Denmark)

    Als-Nielsen, J.; Freund, A.K.; Grübel, G.

    1994-01-01

    The undulator X-ray source is an ideal source for many applications: the beam is brilliant, highly collimated in all directions, quasi-monochromatic, pulsed and linearly polarized. Such a precious source can feed several independently operated instruments by utilizing a downstream series of X......-ray transparent monochromator crystals. Diamond in particular is an attractive monochromator as it is rather X-ray transparent and can be fabricated to a high degree of crystal perfection. Moreover, it has a very high heat conductivity and a rather small thermal expansion so the beam X-ray heat load problem...

  15. Fluorescence-type Monochromatic X-ray Beam-position Monitor with High-spatial Resolution for the NSLS-II Beamlines

    International Nuclear Information System (INIS)

    Yoon, Phil S.; Siddons, D. Peter

    2010-01-01

    We developed a fluorescence-type monochromatic X-ray beam-position monitor (X-BPM) with high-spatial resolution for end-station experiments at the initial project beamlines of the NSLS-II. We designed a ring array of multi-segmented Si PIN-junction photodiodes to use as a position sensor. Further, we integrated a low-noise charge-preamplification HERMES4 ASIC chip into an electronic readout system for photon-counting application. A series of precision measurements to characterize electronically the Si-photodiode sensor and the ASIC chip demonstrated that the inherent noise from the detector system is sufficiently low to meet our stringent requirements. Using a Gaussian beam, we parametrically modeled the optimum working distance to ensure the detector's best performance. Based upon the results from the parametric modeling, prototypes of the next versions of the X-BPM are being developed. In this paper, we describe the methodology for developing the new compact monochromatic X-ray BPM, including its instrumentation, detector modeling, and future plan.

  16. An experimental and Monte Carlo investigation of the energy dependence of alanine/EPR dosimetry: I. Clinical x-ray beams

    International Nuclear Information System (INIS)

    Zeng, G G; McEwen, M R; Rogers, D W O; Klassen, N V

    2004-01-01

    The energy dependence of alanine/EPR dosimetry, in terms of absorbed dose-to-water for clinical 6, 10, 25 MV x-rays and 60 Co rays was investigated by measurements and Monte Carlo (MC) calculations. The dose rates were traceable to the NRC primary standard for absorbed dose, a sealed water calorimetry. The electron paramagnetic resonance (EPR) spectra of irradiated pellets were measured using a Bruker EMX 081 EPR spectrometer. The DOSRZnrc Monte Carlo code of the EGSnrc system was used to simulate the experimental conditions with BEAM code calculated input spectra of x-rays and γ-rays. Within the experimental uncertainty of 0.5%, the alanine EPR response to absorbed dose-to-water for x-rays was not dependent on beam quality from 6 MV to 25 MV, but on average, it was about 0.6% lower than its response to 60 Co gamma rays. Combining experimental data with Monte Carlo calculations, it is found that the alanine/EPR response per unit absorbed dose-to-alanine is the same for clinical x-rays and 60 Co gamma rays within the uncertainty of 0.6%. Monte Carlo simulations showed that neither the presence of PMMA holder nor varying the dosimeter thickness between 1 mm and 5 mm has significant effect on the energy dependence of alanine/EPR dosimetry within the calculation uncertainty of 0.3%

  17. X-ray face mask and chest shield device

    International Nuclear Information System (INIS)

    Moti, S.

    1981-01-01

    A protective face mask is designed to shield an x-ray technician or machine operator primarily from random secondary or scatter x-rays deflected towards his face, head and neck by the table, walls, equipment and other reflecting elements in an x-ray room or chamber. The face mask and chest shield device can be mounted on a patient's shoulders in reverse attitude to protect the back of a patient's head and neck from the x-ray beam. The face mask is relatively or substantially transparent and contains lead in combination with a plastic ionomer or comonomer, which to a degree absorbs or resists penetration of the random deflected secondary or scatter x-rays or the x-ray beam through the mask. The face mask is removably attachable to the chest shield for easy application of the device to and support upon the shoulders of the technician or the patient. (author)

  18. 50 μm pixel pitch wafer-scale CMOS active pixel sensor x-ray detector for digital breast tomosynthesis.

    Science.gov (United States)

    Zhao, C; Konstantinidis, A C; Zheng, Y; Anaxagoras, T; Speller, R D; Kanicki, J

    2015-12-07

    Wafer-scale CMOS active pixel sensors (APSs) have been developed recently for x-ray imaging applications. The small pixel pitch and low noise are very promising properties for medical imaging applications such as digital breast tomosynthesis (DBT). In this work, we evaluated experimentally and through modeling the imaging properties of a 50 μm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). A modified cascaded system model was developed for CMOS APS x-ray detectors by taking into account the device nonlinear signal and noise properties. The imaging properties such as modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE) were extracted from both measurements and the nonlinear cascaded system analysis. The results show that the DynAMITe x-ray detector achieves a high spatial resolution of 10 mm(-1) and a DQE of around 0.5 at spatial frequencies  CMOS APS x-ray detector, image aquisition geometry and image reconstruction techniques should be considered.

  19. X-ray simulation development

    International Nuclear Information System (INIS)

    Posey, L.D.; Tollefsrud, P.B.; Woodall, H.W.; McDaniel, D.H.; Allred, R.E.

    1975-01-01

    Design modifications are discussed for an electron beam accelerator used as a Bremsstrahlung x-ray source. The primary goal of the program, to obtain a reliable 5 cal/gm exposure capability, can be accomplished with beam compression by an external magnetic guide field. Initial operating characteristics and performance improvements are presented

  20. Refractive optics to compensate x-ray mirror shape-errors

    Science.gov (United States)

    Laundy, David; Sawhney, Kawal; Dhamgaye, Vishal; Pape, Ian

    2017-08-01

    Elliptically profiled mirrors operating at glancing angle are frequently used at X-ray synchrotron sources to focus X-rays into sub-micrometer sized spots. Mirror figure error, defined as the height difference function between the actual mirror surface and the ideal elliptical profile, causes a perturbation of the X-ray wavefront for X- rays reflecting from the mirror. This perturbation, when propagated to the focal plane results in an increase in the size of the focused beam. At Diamond Light Source we are developing refractive optics that can be used to locally cancel out the wavefront distortion caused by figure error from nano-focusing elliptical mirrors. These optics could be used to correct existing optical components on synchrotron radiation beamlines in order to give focused X-ray beam sizes approaching the theoretical diffraction limit. We present our latest results showing measurement of the X-ray wavefront error after reflection from X-ray mirrors and the translation of the measured wavefront into a design for refractive optical elements for correction of the X-ray wavefront. We show measurement of the focused beam with and without the corrective optics inserted showing reduction in the size of the focus resulting from the correction to the wavefront.

  1. Nanoscale radiation transport and clinical beam modeling for gold nanoparticle dose enhanced radiotherapy (GNPT) using X-rays.

    Science.gov (United States)

    Zygmanski, Piotr; Sajo, Erno

    2016-01-01

    We review radiation transport and clinical beam modelling for gold nanoparticle dose-enhanced radiotherapy using X-rays. We focus on the nanoscale radiation transport and its relation to macroscopic dosimetry for monoenergetic and clinical beams. Among other aspects, we discuss Monte Carlo and deterministic methods and their applications to predicting dose enhancement using various metrics.

  2. Gamma-H2AX foci in cells exposed to a mixed beam of X-rays and alpha particles

    Science.gov (United States)

    2012-01-01

    Background Little is known about the cellular effects of exposure to mixed beams of high and low linear energy transfer radiation. So far, the effects of combined exposures have mainly been assessed with clonogenic survival or cytogenetic methods, and the results are contradictory. The gamma-H2AX assay has up to now not been applied in this context, and it is a promising tool for investigating the early cellular response to mixed beam irradiation. Purpose To determine the dose response and repair kinetics of gamma-H2AX ionizing radiation-induced foci in VH10 human fibroblasts exposed to mixed beams of 241Am alpha particles and X-rays. Results VH10 human fibroblasts were irradiated with each radiation type individually or both in combination at 37°C. Foci were scored for repair kinetics 0.5, 1, 3 and 24 h after irradiation (one dose per irradiation type), and for dose response at the 1 h time point. The dose response effect of mixed beam was additive, and the relative biological effectiveness for alpha particles (as compared to X-rays) was of 0.76 ± 0.52 for the total number of foci, and 2.54 ± 1.11 for large foci. The repair kinetics for total number of foci in cells exposed to mixed beam irradiation was intermediate to that of cells exposed to alpha particles and X-rays. However, for mixed beam-irradiated cells the frequency and area of large foci were initially lower than predicted and increased during the first 3 hours of repair (while the predicted number and area did not). Conclusions The repair kinetics of large foci after mixed beam exposure was significantly different from predicted based on the effect of the single dose components. The formation of large foci was delayed and they did not reach their maximum area until 1 h after irradiation. We hypothesize that the presence of low X-ray-induced damage engages the DNA repair machinery leading to a delayed DNA damage response to the more complex DNA damage induced by alpha particles. PMID:23121736

  3. Intercomparison of ionization chambers in standard X-ray beams, at radiotherapy, diagnostic radiology and radioprotection levels

    International Nuclear Information System (INIS)

    Bessa, Ana Carolina Moreira de

    2007-01-01

    Since the calibration of radiation measurement instruments and the knowledge of their major characteristics are very important subjects, several different types of ionization chambers were inter compared in terms of their calibration coefficients and their energy dependence, in radiotherapy, diagnostic radiology and radioprotection standard beams. An intercomparison of radionuclide calibrators for nuclear medicine was performed, using three radionuclides: 67 Ga, 201 Tl and 99m Tc; the results obtained were all within the requirements of the national standard CNEN-NE-3.05. In order to complete the range of radiation qualities of the Calibration Laboratory of IPEN, standard radiation beam qualities, radiation protection and low energy radiation therapy levels, were established, according international recommendations. Three methodologies for the calibration of unsealed ionization chambers in X-ray beams were studied and compared. A set of Victoreen ionization chambers, specially designed for use in laboratorial intercomparisons, was submitted to characterization tests. The performance of these Victoreen ionization chambers showed that they are suitable for use in radioprotection beams, because the results obtained agree with international recommendations. However, these Victoreen ionization chambers can be used in radiotherapy and diagnostic radiology beams only with some considerations, since their performance in these beams, especially in relation to the energy dependence and stabilization time tests, did not agree with the international recommendations for dosimeters used in radiotherapy and diagnostic radiology beams. This work presents data on the performance of several types of ionization chambers in different X-ray beams, that may be useful for choosing the appropriate instrument for measurements in ionizing radiation beams. (author)

  4. Intercomparison of ionization chambers in standard X-ray beams, at radiotherapy, diagnostic radiology and radioprotection levels

    International Nuclear Information System (INIS)

    Bessa, Ana Carolina Moreira de

    2006-01-01

    Since the calibration of radiation measurement instruments and the knowledge of their major characteristics are very important subjects, several different types of ionization chambers were intercompared in terms of their calibration coefficients and their energy dependence, in radiotherapy, diagnostic radiology and radioprotection standard beams. An intercomparison of radionuclide calibrators for nuclear medicine was performed, using three radionuclides: 67 Ga, 201 Tl and 99m Tc; the results obtained were all within the requirements of the national standard CNEN-NE-3.05. In order to complete the range of radiation qualities of the Calibration Laboratory of IPEN, standard radiation beam qualities, radiation protection and low energy radiation therapy levels, were established, according international recommendations. Three methodologies for the calibration of unsealed ionization chambers in X-ray beams were studied and compared. A set of Victoreen ionization chambers, specially designed for use in laboratorial intercomparisons, was submitted to characterization tests. The performance of these Victoreen ionization chambers showed that they are suitable for use in radioprotection beams, because the results obtained agree with international recommendations. However, these Victoreen ionization chambers can be used in radiotherapy and diagnostic radiology beams only with some considerations, since their performance in these beams, especially in relation to the energy dependence and stabilization time tests, did not agree with the international recommendations for dosimeters used in radiotherapy and diagnostic radiology beams. This work presents data on the performance of several types of ionization chambers in different X-ray beams, that may be useful for choosing the appropriate instrument for measurements in ionizing radiation beams. (author)

  5. Development of improved x-ray optics for analytical x-ray microbeams. CRADA final report for CRADA Number Y-1294-0283

    International Nuclear Information System (INIS)

    Carpenter, D.A.; Gao, N.; Xiao, Q.F.; Ponomarev, I.

    1996-01-01

    The purpose of this CRADA was to develop improved glass capillary, x-ray optics for analytical x-ray microbeam applications. X-Ray Optical Systems, Inc. (XOS) designed and fabricated capillary optics and LMES tested those optics for x-ray microanalytical applications using its unique X-Ray Microprobe. Tapered capillaries with 3-microm and 8-microm output openings were fabricated and tested. The tapered capillaries had better spectral quality for x-ray microfluorescence (XRMF) analysis, than non-tapered, straight capillaries that are currently used in the system. X-ray beam count-rates for the tapered capillaries were also greater than the straight capillaries. Two monolithic, polycapillary optics were fabricated and tested. The polycapillary optics produced focal spots of 40 and 100 microm. Beam intensities for the polycapillaries were, respective, 44 and 18 times the intensities found in straight 50-microm and 100-microm capillaries. High-sensitivity scanning will be possible because of the enhanced intensity of the polycapillary optic. LMES and the DP program will benefit from improved capabilities for nondestructive x-ray microanalysis, while XOS will benefit from test results that will enhance the marketability of their products

  6. Is there any advantage of CT based 3-dimensional conformal planning over conventional orthogonal x-ray based planning in HDR brachytherapy in breast cancer

    International Nuclear Information System (INIS)

    Biswal, B.M.; Idris, N.R.; Zakaria, A.B.; Khairul, N.

    2003-01-01

    The conventional brachytherapy dose calculation is based on a particular brachytherapy rule or individual dosimetry based on the reconstruction of the sources from the orthogonal films. In the recent years many centers are using CT based 3D conformal brachytherapy in order to improve the dosimetric outcome of a given plan. Here we would like to present our experience on the use of both techniques to deliver HDR interstitial brachytherapy as boost in early breast cancer. From January 2001 to January 2003, we treated 4 breast cancer patients using conventional orthogonal x-rays and CT scan in 3 cases for the treatment plan. All patients received an external beam radiotherapy dose of 46 Gy in 23 fractions over 4.5 weeks to the whole breast using 6 MV photon beam. Subsequently the primary lesion was supplimented with HDR brachytherapy to a dose of 2.5 Gy BID for 3 consecutive days using a (192)Ir microSelectronHDR. The dose prescription was individualized to encompass the tumor volume with a 10 mm margin. The differences of the dosimetric outcome were compared. All patients completed above schedule of radiotherapy. The primary was implanted with single plane in 3 patients and multiplane implant in 4 patients. Orthogonal x-ray based localization was performed in 4 patients and CT scan based localization in 3 cases. Three patients were implanted single plane and 4 patients with multiplane implants with a median catheter number of 9 (range 6-14). The 3D conformal dose optimization was performed using Nucletron planning system (Plato). The mean 100% and 150% isodose volume was 67.3 cm 3 and 31.25cm 3 respectively. The identification of primary tumor volume, organ at risk, and identification of afterloading catheters were superior in CT based plan than conventional planning. CT scan based 3D conformal brachytherapy planning give better identification of tumor volume and its curvature, decrease the time to identify the sources and evaluate the radiation dose to organs at

  7. Bremsstrahlung hard x-ray source driven by an electron beam from a self-modulated laser wakefield accelerator

    Science.gov (United States)

    Lemos, N.; Albert, F.; Shaw, J. L.; Papp, D.; Polanek, R.; King, P.; Milder, A. L.; Marsh, K. A.; Pak, A.; Pollock, B. B.; Hegelich, B. M.; Moody, J. D.; Park, J.; Tommasini, R.; Williams, G. J.; Chen, Hui; Joshi, C.

    2018-05-01

    An x-ray source generated by an electron beam produced using a Self-Modulated Laser Wakefield Accelerator (SM-LWFA) is explored for use in high energy density science facilities. By colliding the electron beam, with a maximum energy of 380 MeV, total charge of >10 nC and a divergence of 64 × 100 mrad, from a SM-LWFA driven by a 1 ps 120 J laser, into a high-Z foil, an x/gamma-ray source was generated. A broadband bremsstrahlung energy spectrum with temperatures ranging from 0.8 to 2 MeV was measured with an almost 2 orders of magnitude flux increase when compared with other schemes using LWFA. GEANT4 simulations were done to calculate the source size and divergence.

  8. Cone-beam micro computed tomography dedicated to the breast.

    Science.gov (United States)

    Sarno, Antonio; Mettivier, Giovanni; Di Lillo, Francesca; Cesarelli, Mario; Bifulco, Paolo; Russo, Paolo

    2016-12-01

    We developed a scanner for micro computed tomography dedicated to the breast (BµCT) with a high resolution flat-panel detector and a microfocus X-ray tube. We evaluated the system spatial resolution via the 3D modulation transfer function (MTF). In addition to conventional absorption-based X-ray imaging, such a prototype showed capabilities for propagation-based phase-contrast and related edge enhancement effects in 3D imaging. The system limiting spatial resolution is 6.2mm -1 (MTF at 10%) in the vertical direction and 3.8mm -1 in the radial direction, values which compare favorably with the spatial resolution reached by mini focus breast CT scanners of other groups. The BµCT scanner was able to detect both microcalcification clusters and masses in an anthropomorphic breast phantom at a dose comparable to that of two-view mammography. The use of a breast holder is proposed in order to have 1-2min long scan times without breast motion artifacts. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  9. Performances for confocal X-ray diffraction technology based on polycapillary slightly focusing X-ray optics

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hehe; Liu, Zhiguo [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Sun, Tianxi, E-mail: stxbeijing@163.com [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Peng, Song [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Ma, Yongzhong [Center for Disease Control and Prevention of Beijing, Beijing 100013 (China); Sun, Weiyuan; Li, Yude; Lin, Xiaoyan; Zhao, Weigang; Zhao, Guangcui; Luo, Ping; Pan, Qiuli; Ding, Xunliang [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2013-09-21

    The confocal X-ray diffraction (XRD) technology based on a polycapillary slightly focusing X-ray lens (PSFXRL) in excitation channel and a polycapillary parallel X-ray lens (PPXRL) with a long input focal distance in detection channel was developed. The output focal spot of the PSFXRL and the input focal spot of the PPXRL were adjusted in confocal configuration, and only the X-rays from the volume overlapped by these foci could be accordingly detected. This confocal configuration was helpful in decreasing background. The convergence of the beam focused by the PSFXRL and divergence of the beam which could be collected by the PPXRL with a long input focal distance were both about 9 mrad at 8 keV. This was helpful in improving the resolution of lattice spacing of this confocal XRD technology. The gain in power density of such PSFXRL and PPXRL was about 120 and 7 at 11 keV, respectively, which was helpful in using the low power source to perform XRD analysis efficiently. The performances of this confocal XRD technology were provided, and some common plastics were analyzed. The experimental results demonstrated that the confocal diffraction technology base on polycapillary slightly focusing X-ray optics had wide potential applications.

  10. Propagation of modulated electron and X-ray beams through matter and interactions with radio-frequency structures

    Science.gov (United States)

    Harris, J. R.; Miller, R. B.

    2018-02-01

    The generation and evolution of modulated particle beams and their interactions with resonant radiofrequency (RF) structures are of fundamental interest for both particle accelerator and vacuum electronic systems. When the constraint of propagation in a vacuum is removed, the evolution of such beams can be greatly affected by interactions with matter including scattering, absorption, generation of atmospheric plasma, and the production of multiple generations of secondary particles. Here, we study the propagation of 21 MeV and 25 MeV electron beams produced in S-band and L-band linear accelerators, and their interaction with resonant RF structures, under a number of combinations of geometry, including transmission through both air and metal. Both resonant and nonresonant interactions were observed, with the resonant interactions indicating that the RF modulation on the electron beam is at least partially preserved as the beam propagates through air and metal. When significant thicknesses of metal are placed upstream of a resonant structure, preventing any primary beam electrons from reaching the structure, RF signals could still be induced in the structures. This indicated that the RF modulation present on the electron beam was also impressed onto the x-rays generated when the primary electrons were stopped in the metal, and that this RF modulation was also present on the secondary electrons generated when the x-rays struck the resonant structures. The nature of these interactions and their sensitivities to changes in system configurations will be discussed.

  11. Multiple x-ray diffraction simulation and applications

    International Nuclear Information System (INIS)

    Costa, C.A.B.S. da.

    1989-09-01

    A computer program (MULTX) was implemented for simulation X-ray multiple diffraction diagrams in Renninger geometries. The program uses the X-ray multiple diffraction theory for imperfect crystals. The iterative calculation of the intensities is based on the Taylor series general term, and the primary beam power expansion is given as function of the beam x penetration in the crystal surface. This development allows to consider the simultaneous interaction of the beams involved in the multiple diffraction phenomenon. The simulated diagrams are calculated point-to-point and the tests for the Si and GaAs presented good reproduction of the experimental diagrams for different primary reflections. (L.C.J.A.)

  12. TAILORING X-RAY BEAM ENERGY SPECTRUM TO ENHANCE IMAGE QUALITY OF NEW RADIOGRAPHY CONTRAST AGENTS BASED ON GD OR OTHER LANTHANIDES.

    Energy Technology Data Exchange (ETDEWEB)

    DILMANIAN,F.A.; WEINMANN,H.J.; ZHONG,Z.; BACARIAN,T.; RIGON,L.; BUTTON,T.M.; REN,B.; WU,X.Y.; ZHONG,N.; ATKINS,H.L.

    2001-02-17

    Gadovist, a 1.0-molar Gd contrast agent from Schering AG, Berlin Germany, in use in clinical MPI in Europe, was evaluated as a radiography contrast agent. In a collaboration with Brookhaven National Laboratory (BNL), Schering AG is developing several such lanthanide-based contrast agents, while BNL evaluates them using different x-my beam energy spectra. These energy spectra include a ''truly'' monochromatic beam (0.2 keV energy bandwidth) from the National Synchrotron Light Source (NSLS), BNL, tuned above the Gd K-edge, and x-ray-tube beams from different kVp settings and beam filtrations. Radiographs of rabbits' kidneys were obtained with Gadovist at the NSLS. Furthermore, a clinical radiography system was used for imaging rabbits' kidneys comparing Gadovist and Conray, an iodinated contrast agent. The study, using 74 kVp and standard Al beam filter for Conray and 66 kVp and an additional 1.5 mm Cu beam filter for Gadovist, produced comparable images for Gadovist and Conray; the injection volumes were the same, while the radiation absorbed dose for Gadovist was slightly smaller. A bent-crystal silicon monochromator operating in the Laue diffraction mode was developed and tested with a conventional x-ray tube beam; it narrows the energy spectrum to about 4 keV around the anode tungsten's Ku line. Preliminary beam-flux results indicate that the method could be implemented in clinical CT if x-ray tubes with {approximately} twice higher output become available.

  13. A reconstruction method for cone-beam differential x-ray phase-contrast computed tomography.

    Science.gov (United States)

    Fu, Jian; Velroyen, Astrid; Tan, Renbo; Zhang, Junwei; Chen, Liyuan; Tapfer, Arne; Bech, Martin; Pfeiffer, Franz

    2012-09-10

    Most existing differential phase-contrast computed tomography (DPC-CT) approaches are based on three kinds of scanning geometries, described by parallel-beam, fan-beam and cone-beam. Due to the potential of compact imaging systems with magnified spatial resolution, cone-beam DPC-CT has attracted significant interest. In this paper, we report a reconstruction method based on a back-projection filtration (BPF) algorithm for cone-beam DPC-CT. Due to the differential nature of phase contrast projections, the algorithm restrains from differentiation of the projection data prior to back-projection, unlike BPF algorithms commonly used for absorption-based CT data. This work comprises a numerical study of the algorithm and its experimental verification using a dataset measured with a three-grating interferometer and a micro-focus x-ray tube source. Moreover, the numerical simulation and experimental results demonstrate that the proposed method can deal with several classes of truncated cone-beam datasets. We believe that this feature is of particular interest for future medical cone-beam phase-contrast CT imaging applications.

  14. A feasibility study of dynamic stress analysis inside a running internal combustion engine using synchrotron X-ray beams.

    Science.gov (United States)

    Baimpas, Nikolaos; Drakopoulos, Michael; Connolley, Thomas; Song, Xu; Pandazaras, Costas; Korsunsky, Alexander M

    2013-03-01

    The present investigation establishes the feasibility of using synchrotron-generated X-ray beams for time-resolved in situ imaging and diffraction of the interior components of an internal combustion engine during its operation. The demonstration experiment was carried out on beamline I12 (JEEP) at Diamond Light Source, UK. The external hutch of the JEEP instrument is a large-scale engineering test bed for complex in situ processing and simulation experiments. The hutch incorporates a large capacity translation and rotation table and a selection of detectors for monochromatic and white-beam diffraction and imaging. These capabilities were used to record X-ray movies of a motorcycle internal combustion engine running at 1850 r.p.m. and to measure strain inside the connecting rod via stroboscopic X-ray diffraction measurement. The high penetrating ability and high flux of the X-ray beam at JEEP allowed the observation of inlet and outlet valve motion, as well as that of the piston, connecting rod and the timing chain within the engine. Finally, the dynamic internal strain within the moving connecting rod was evaluated with an accuracy of ~50 × 10(-6).

  15. Simulation of enhanced characteristic x rays from a 40-MeV electron beam laser accelerated in plasma

    Directory of Open Access Journals (Sweden)

    L. Nikzad

    2012-02-01

    Full Text Available Simulation of x-ray generation from bombardment of various solid targets by quasimonoenergetic electrons is considered. The electron bunches are accelerated in a plasma produced by interaction of 500 mJ, 30 femtosecond laser pulses with a helium gas jet. These relativistic electrons propagate in the ion channel generated in the wake of the laser pulse. A beam of MeV electrons can interact with targets to generate x-ray radiation with keV energy. The MCNP-4C code based on Monte Carlo simulation is employed to compare the production of bremsstrahlung and characteristic x rays between 10 and 100 keV by using two quasi-Maxwellian and quasimonoenergetic energy distributions of electrons. For a specific electron spectrum and a definite sample, the maximum x-ray flux varies with the target thickness. Besides, by increasing the target atomic number, the maximum x-ray flux is increased and shifted towards a higher energy level. It is shown that by using the quasimonoenergetic electron profile, a more intense x ray can be produced relative to the quasi-Maxwellian profile (with the same total energy, representing up to 77% flux enhancement at K_{α} energy.

  16. Breast density quantification with cone-beam CT: a post-mortem study

    International Nuclear Information System (INIS)

    Johnson, Travis; Ding, Huanjun; Le, Huy Q; Ducote, Justin L; Molloi, Sabee

    2013-01-01

    Forty post-mortem breasts were imaged with a flat-panel based cone-beam x-ray CT system at 50 kVp. The feasibility of breast density quantification has been investigated using standard histogram thresholding and an automatic segmentation method based on the fuzzy c-means algorithm (FCM). The breasts were chemically decomposed into water, lipid, and protein immediately after image acquisition was completed. The per cent fibroglandular volume (%FGV) from chemical analysis was used as the gold standard for breast density comparison. Both image-based segmentation techniques showed good precision in breast density quantification with high linear coefficients between the right and left breast of each pair. When comparing with the gold standard using %FGV from chemical analysis, Pearson's r-values were estimated to be 0.983 and 0.968 for the FCM clustering and the histogram thresholding techniques, respectively. The standard error of the estimate was also reduced from 3.92% to 2.45% by applying the automatic clustering technique. The results of the postmortem study suggested that breast tissue can be characterized in terms of water, lipid and protein contents with high accuracy by using chemical analysis, which offers a gold standard for breast density studies comparing different techniques. In the investigated image segmentation techniques, the FCM algorithm had high precision and accuracy in breast density quantification. In comparison to conventional histogram thresholding, it was more efficient and reduced inter-observer variation. (paper)

  17. Fluorescence detection of white-beam X-ray absorption anisotropy: towards element-sensitive projections of local atomic structure

    Science.gov (United States)

    Korecki, P.; Tolkiehn, M.; Dąbrowski, K. M.; Novikov, D. V.

    2011-01-01

    Projections of the atomic structure around Nb atoms in a LiNbO3 single crystal were obtained from a white-beam X-ray absorption anisotropy (XAA) pattern detected using Nb K fluorescence. This kind of anisotropy results from the interference of X-rays inside a sample and, owing to the short coherence length of a white beam, is visible only at small angles around interatomic directions. Consequently, the main features of the recorded XAA corresponded to distorted real-space projections of dense-packed atomic planes and atomic rows. A quantitative analysis of XAA was carried out using a wavelet transform and allowed well resolved projections of Nb atoms to be obtained up to distances of 10 Å. The signal of nearest O atoms was detected indirectly by a comparison with model calculations. The measurement of white-beam XAA using characteristic radiation indicates the possibility of obtaining element-sensitive projections of the local atomic structure in more complex samples. PMID:21997909

  18. X-ray absorption anisotropy for polychromatic illumination-Crystal views from inside

    International Nuclear Information System (INIS)

    Korecki, P.; Tolkiehn, M.; Novikov, D.V.

    2009-01-01

    We review an atomic resolution imaging method based on the analysis of the fine structure in X-ray absorption anisotropy, which results from incident beam diffraction. For a polychromatic X-ray beam, due to the suppression of higher order diffraction fringes, X-ray absorption anisotropy patterns can be interpreted as distorted real-space projections of the atomic structure around absorbing atoms. A qualitative method for analysis of X-ray absorption anisotropy patterns is presented, based on modeling of X-ray patterns with ray-traced images calculated for clusters around absorbing atoms.

  19. X-ray radiography with highly charged ions

    Science.gov (United States)

    Marrs, Roscoe E.

    2000-01-01

    An extremely small (1-250 micron FWHM) beam of slow highly charged ions deexciting on an x-ray production target generates x-ray monochromatic radiation that is passed through a specimen and detected for imaging. The resolution of the x-ray radiograms is improved and such detection is achieved with relatively low dosages of radiation passing through the specimen. An apparatus containing an electron beam ion trap (and modifications thereof) equipped with a focusing column serves as a source of ions that generate radiation projected onto an image detector. Electronic and other detectors are able to detect an increased amount of radiation per pixel than achieved by previous methods and apparati.

  20. Bi-directional x-ray phase-contrast mammography.

    Directory of Open Access Journals (Sweden)

    Kai Scherer

    Full Text Available Phase-contrast x-ray imaging is a promising improvement of conventional absorption-based mammography for early tumor detection. This potential has been demonstrated recently, utilizing structured gratings to obtain differential phase and dark-field scattering images. However, the inherently anisotropic imaging sensitivity of the proposed mono-directional approach yields only insufficient diagnostic information, and has low diagnostic sensitivity to highly oriented structures. To overcome these limitations, we present a two-directional x-ray phase-contrast mammography approach and demonstrate its advantages by applying it to a freshly dissected, cancerous mastectomy breast specimen. We illustrate that the two-directional scanning procedure overcomes the insufficient diagnostic value of a single scan, and reliably detects tumor structures, independently from their orientation within the breast. Our results indicate the indispensable diagnostic necessity and benefit of a multi-directional approach for x-ray phase-contrast mammography.

  1. A beam optics study of a modular multi-source X-ray tube for novel computed tomography applications

    Science.gov (United States)

    Walker, Brandon J.; Radtke, Jeff; Chen, Guang-Hong; Eliceiri, Kevin W.; Mackie, Thomas R.

    2017-10-01

    A modular implementation of a scanning multi-source X-ray tube is designed for the increasing number of multi-source imaging applications in computed tomography (CT). An electron beam array coupled with an oscillating magnetic deflector is proposed as a means for producing an X-ray focal spot at any position along a line. The preliminary multi-source model includes three thermionic electron guns that are deflected in tandem by a slowly varying magnetic field and pulsed according to a scanning sequence that is dependent on the intended imaging application. Particle tracking simulations with particle dynamics analysis software demonstrate that three 100 keV electron beams are laterally swept a combined distance of 15 cm over a stationary target with an oscillating magnetic field of 102 G perpendicular to the beam axis. Beam modulation is accomplished using 25 μs pulse widths to a grid electrode with a reverse gate bias of -500 V and an extraction voltage of +1000 V. Projected focal spot diameters are approximately 1 mm for 138 mA electron beams and the stationary target stays within thermal limits for the 14 kW module. This concept could be used as a research platform for investigating high-speed stationary CT scanners, for lowering dose with virtual fan beam formation, for reducing scatter radiation in cone-beam CT, or for other industrial applications.

  2. Dosimetry and narrow X-ray beams, produced by particle linear accelerator for use in radiosurgery

    International Nuclear Information System (INIS)

    Campos, J.C.F.; Vizeu, D.M.

    1987-01-01

    The principal characteristics of dosimetry and narrow X-ray beams(4Mv) monitoring are investigated for use in estereotatic radiosurgery. An additional collimator system and a estereotatic system (Leksell type) are presented. Dosimetric parameters like tissue-air ratio, peak scatter factor, isodose curves are studied. (M.A.C.) [pt

  3. The APS x-ray undulator photon beam position monitor and tests at CHESS and NSLS

    International Nuclear Information System (INIS)

    Shu, D.; Rodricks, B.; Barraza, J.; Sanchez, T.; Kuzay, T.M.

    1992-01-01

    The advent of third generation synchrotron radiation sources, like the Advanced Photon Source (APS), will provide significant increases in brilliance over existing synchrotron sources. The APS x-ray undulators will increase the brilliance in the 3-40 KeV range by several orders of magnitude. Thus, the design of the photon beam position monitor is a challenging engineering task. The beam position monitors must withstand the high thermal load, be able to achieve sub-micron spatial resolution while maintaining their stability, and be compatible with both undulators and wigglers. A preliminary APS prototype photon beam position monitor consisting of a CVD-diamond-based, tungsten-coated blade was tested on the APS/CHESS undulator at the Cornell High Energy Synchrotron Radiation Source (CHESS) and on the NSLS X-13 undulator beamline. Results from these tests, as well as the design of this prototype APS photon beam position monitor, will be discussed in this paper

  4. The APS X-ray undulator photon beam position monitor and tests at CHESS and NSLS

    International Nuclear Information System (INIS)

    Shu, D.; Rodricks, B.; Barraza, J.; Sanchez, T.; Kuzay, T.M.

    1992-01-01

    The advent of thirs generation synchrotron sources, like the Advanced Photon Source (APS), will provide significant increases in brilliance over existing synchrotron sources. The APS X-ray undulators will increase the brilliance in the 3-40 keV range by several orders of magnitude. Thus, the design of the photon beam position monitor is a challenging engineering task. The beam position monitors must withstand the high thermal load, be able to achieve submicron spatial resolution while maintaining their stability, and be compatible with both undulators and wigglers. A preliminary APS prototype photon beam position monitor consisting of a CVD-diamond-based, tungsten-coated blade was tested on the APS/CHESS undulator at the Cornell High Energy Synchrotron Radiation Source (CHESS) and on the NSLS X-13 undulator beamline. Results from these tests, as well as the design of this prototype APS photon beam position monitor, will be discussed in this paper. (orig.)

  5. Submicron X-ray diffraction

    International Nuclear Information System (INIS)

    MacDowell, Alastair; Celestre, Richard; Tamura, Nobumichi; Spolenak, Ralph; Valek, Bryan; Brown, Walter; Bravman, John; Padmore, Howard; Batterman, Boris; Patel, Jamshed

    2000-01-01

    At the Advanced Light Source in Berkeley the authors have instrumented a beam line that is devoted exclusively to x-ray micro diffraction problems. By micro diffraction they mean those classes of problems in Physics and Materials Science that require x-ray beam sizes in the sub-micron range. The instrument is for instance, capable of probing a sub-micron size volume inside micron sized aluminum metal grains buried under a silicon dioxide insulating layer. The resulting Laue pattern is collected on a large area CCD detector and automatically indexed to yield the grain orientation and deviatoric (distortional) strain tensor of this sub-micron volume. A four-crystal monochromator is then inserted into the beam, which allows monochromatic light to illuminate the same part of the sample. Measurement of diffracted photon energy allows for the determination of d spacings. The combination of white and monochromatic beam measurements allow for the determination of the total strain/stress tensor (6 components) inside each sub-micron sized illuminated volume of the sample

  6. Accelerator X-ray sources

    International Nuclear Information System (INIS)

    Talman, R.

    2006-01-01

    This is the first monograph to cover in-depth the production of brilliant x-ray beams in accelerators, with emphasis on fourth generation designs, such as energy recovery linacs (ERL), fast cycling storage rings, and free electron lasers (FEL). Going beyond existing treatments of the influence of synchroton radiation on accelerator operation, special emphasis is placed on the design of undulator-based beam lines, and the physics of undulator radiation. Starting from the unified treatment of electron and photon beams both as bunches of particles and as waves, the author proceeds to analyse the main components, from electron gun, through linac and arc lattice, to the x-ray beam line. Designs are given for both an ERL and a more conventional storage ring complex, and their anticipated properties are compared in detail. Space charge effects are analysed with emphasis on coherent synchrotron radiation and emittance dilution. Beam diagnostics using synchrotron radiation or laser wire (Compton scattering) are also analysed in detail. Written primarily for general, particle, and radiation physicists, the systematic treatment adopted by the work makes it equally suitable as an advanced textbook for young researchers. (orig.)

  7. Correlation of photon beam motion with vacuum chamber cooling on the NSLS x-ray ring

    International Nuclear Information System (INIS)

    Johnson, E.D.; Fauchet, A.M.; Zhang, Xiaohao.

    1991-01-01

    The NSLS X-ray ring exhibits a direct correlation between photon beam motion, and distortion of the ring vacuum chamber induced by fluctuations in the cooling system. We have made long term measurements of photon beam vertical position, accelerator vacuum chamber motion, process water temperatures, and angular motions of the magnets around one superperiod of the NSLS x-ray ring. Short term transients in water temperature cause deflection of the ring vacuum chamber which have in turn been shown to induce very small angular rotations of the magnets, on the order of 10 micro-radians. A larger and more difficult to correct effect is the drift in beam position over the course of a fill. This problem has been shown to be related to the thermal gradients that develop across the vacuum chamber which, as a consequence of the configuration of the chamber cooling, depend upon stored current. Orbit simulations based upon the measured rotations are in agreement with the observed beam motions, and reveal that certain patterns of correlated motions of the magnets can produce much larger errors than random motion or concerted motion of all the magnets. During the course of these measurements global orbit feedback was installed, and found to significantly reduce the orbit errors which could not be corrected at their source

  8. X-raying with low dose irradiation

    International Nuclear Information System (INIS)

    Malevich, E.E.; Kisel, E.M.; Shpita, I.D.; Lazovsky, A.S.

    2001-01-01

    With the purpose of the improvement of diagnostics quality and reduction of beam load on a patient in modern x-ray devices pulse x-raying is applied. It is based on the using of radiation pulses with various frequencies of intervals between them instead of continuous radiation. At pulse x-raying with the net control the principle of filling of an interval is used, when the information about the image, received with the last pulse, get into memory and is displayed before occurrence of other pulse. It creates impression of the continuous image even at low frequency of pulses. Due to the unique concept of the simultaneous (double) control, all of 3 parameters, which define the quality of the image (pressure(voltage), force of a current and length of a pulse), are adjusted automatically at each pulse, thus optimum adaptation to varied thickness of object during dynamic researches occurs. At x-raying pulse the presence of a free interval from x-ray radiation between two pulses results in the decrease of a radiation dose. Pulsing occurs some times per one second with equal intervals between pulses. Thus, the degree of decrease irradiation dose depends on duration of a pause between pulses. On the screen the image of last pulse before occurrence of the following is kept and repeats. The principle of x-raying pulse was realized in system Grid Controlled Fluoroscopy by the firm 'Philips Medi zin Systeme'. In the x-ray tube of this system inclusion and de energizing of radiation occurs directly on a source. Electron cloud is broken off by the special grid, which is located between the cathode and the anode and operates as a barrier. Thus the tube continues to be energized. In usual devices for pulses formation is used generator pulsation system, which at increase and attenuation of a x-ray pulse results in occurrence of the increasing and fading radiation which are not participating in the formation of the image, but creating beam load on the patient and the personnel. Thus

  9. Phase-contrast tomographic imaging using an X-ray interferometer

    Energy Technology Data Exchange (ETDEWEB)

    Momose, A. [Hitachi Ltd, Advanced Research Lab., Saitama (Japan); Takeda, T.; Itai, Y. [Univ. of Tsukuba, Inst. of Clinical Medicine, Ibaraki (Japan); Yoneyama, A. [Hitachi Ltd, Central Resarch Lab., Tokyo (Japan); Hirano, K. [High Energy Accelerator Research Organization, Inst. of Materials Structure Science, Ibaraki (Japan)

    1998-05-01

    Apparatus for phase-contrast X-ray computed tomography using a monolithic X-ray interferometer is presented with some observational results for human breast tissues. Structures characteristic of the tissues were revealed in the phase-contrast tomograms. The procedure of image analysis consists of phase retrieval from X-ray interference patterns and tomographic image reconstruction from the retrieved phase shift. Next, feasibility of phase-contrast imaging using a two-crystal X-ray interferometer was studied aiming at in vivo observation in the future. In a preliminary study, the two-crystal X-ray interferometer was capable of generating fringes of 70% visibility using synchrotron X-rays. 35 refs.

  10. Phase-contrast tomographic imaging using an X-ray interferometer

    International Nuclear Information System (INIS)

    Momose, A.; Takeda, T.; Itai, Y.; Yoneyama, A.; Hirano, K.

    1998-01-01

    Apparatus for phase-contrast X-ray computed tomography using a monolithic X-ray interferometer is presented with some observational results for human breast tissues. Structures characteristic of the tissues were revealed in the phase-contrast tomograms. The procedure of image analysis consists of phase retrieval from X-ray interference patterns and tomographic image reconstruction from the retrieved phase shift. Next, feasibility of phase-contrast imaging using a two-crystal X-ray interferometer was studied aiming at in vivo observation in the future. In a preliminary study, the two-crystal X-ray interferometer was capable of generating fringes of 70% visibility using synchrotron X-rays

  11. Accelerator x-ray sources

    CERN Document Server

    Talman, Richard

    2007-01-01

    This first book to cover in-depth the generation of x-rays in particle accelerators focuses on electron beams produced by means of the novel Energy Recovery Linac (ERL) technology. The resulting highly brilliant x-rays are at the centre of this monograph, which continues where other books on the market stop. Written primarily for general, high energy and radiation physicists, the systematic treatment adopted by the work makes it equally suitable as an advanced textbook for young researchers.

  12. Simulating systematic errors in X-ray absorption spectroscopy experiments: Sample and beam effects

    Energy Technology Data Exchange (ETDEWEB)

    Curis, Emmanuel [Laboratoire de Biomathematiques, Faculte de Pharmacie, Universite Rene, Descartes (Paris V)-4, Avenue de l' Observatoire, 75006 Paris (France)]. E-mail: emmanuel.curis@univ-paris5.fr; Osan, Janos [KFKI Atomic Energy Research Institute (AEKI)-P.O. Box 49, H-1525 Budapest (Hungary); Falkenberg, Gerald [Hamburger Synchrotronstrahlungslabor (HASYLAB), Deutsches Elektronen-Synchrotron (DESY)-Notkestrasse 85, 22607 Hamburg (Germany); Benazeth, Simone [Laboratoire de Biomathematiques, Faculte de Pharmacie, Universite Rene, Descartes (Paris V)-4, Avenue de l' Observatoire, 75006 Paris (France); Laboratoire d' Utilisation du Rayonnement Electromagnetique (LURE)-Ba-hat timent 209D, Campus d' Orsay, 91406 Orsay (France); Toeroek, Szabina [KFKI Atomic Energy Research Institute (AEKI)-P.O. Box 49, H-1525 Budapest (Hungary)

    2005-07-15

    The article presents an analytical model to simulate experimental imperfections in the realization of an X-ray absorption spectroscopy experiment, performed in transmission or fluorescence mode. Distinction is made between sources of systematic errors on a time-scale basis, to select the more appropriate model for their handling. For short time-scale, statistical models are the most suited. For large time-scale, the model is developed for sample and beam imperfections: mainly sample inhomogeneity, sample self-absorption, beam achromaticity. The ability of this model to reproduce the effects of these imperfections is exemplified, and the model is validated on real samples. Various potential application fields of the model are then presented.

  13. Simulating systematic errors in X-ray absorption spectroscopy experiments: Sample and beam effects

    International Nuclear Information System (INIS)

    Curis, Emmanuel; Osan, Janos; Falkenberg, Gerald; Benazeth, Simone; Toeroek, Szabina

    2005-01-01

    The article presents an analytical model to simulate experimental imperfections in the realization of an X-ray absorption spectroscopy experiment, performed in transmission or fluorescence mode. Distinction is made between sources of systematic errors on a time-scale basis, to select the more appropriate model for their handling. For short time-scale, statistical models are the most suited. For large time-scale, the model is developed for sample and beam imperfections: mainly sample inhomogeneity, sample self-absorption, beam achromaticity. The ability of this model to reproduce the effects of these imperfections is exemplified, and the model is validated on real samples. Various potential application fields of the model are then presented

  14. Dual energy scanning beam laminographic x-radiography

    Science.gov (United States)

    Majewski, S.; Wojcik, R.F.

    1998-04-21

    A multiple x-ray energy level imaging system includes a scanning x-ray beam and two detector design having a first low x-ray energy sensitive detector and a second high x-ray energy sensitive detector. The low x-ray energy detector is placed next to or in front of the high x-ray energy detector. The low energy sensitive detector has small stopping power for x-rays. The lower energy x-rays are absorbed and converted into electrical signals while the majority of the higher energy x-rays pass through undetected. The high energy sensitive detector has a large stopping power for x-rays as well as it having a filter placed between it and the object to absorb the lower energy x-rays. In a second embodiment; a single energy sensitive detector is provided which provides an output signal proportional to the amount of energy in each individual x-ray it absorbed. It can then have an electronic threshold or thresholds set to select two or more energy ranges for the images. By having multiple detectors located at different positions, a dual energy laminography system is possible. 6 figs.

  15. Precision X-ray spectroscopy on 8.5 MeV/amu heavy ions

    International Nuclear Information System (INIS)

    Dietrich, D.D.; Chandler, G.A.; Fortner, R.J.; Hailey, C.J.; Stewart, R.E.

    1985-01-01

    A new experimental capability has been developed at the Lawrence Berkeley Laboratory Super-HILAC to investigate questions relating to high resolution atomic spectroscopy. A key element of these measurements is a dual arm Johann spectrometer. The ion beam passes inside the Rowland circle of two curved crystals which are mounted such that diffracted X-rays have equal and opposite linear Doppler shifts. The X-ray lines are detected with high speed X-ray film mounted on the Rowland circle. The beam-crystal geometry is arranged so a spectral range thetasub(B)proportional30 0 -70 0 is detected. The spectrometer efficiency is high with useful exposures obtained with only 10 mC of beam. A wavelength calibration is obtained by simultaneously exposing the film with diffracted K and L X-rays from an X-ray tube. X-ray lines from the beam are slanted, with respect to the calibration lines, due to Doppler shifts arising from X-rays incident on the crystal at angles other than perpendicular to the diffraction plane. The slope of these lines provides an independent determination of the beam velocity, which is used to correct for the transverse Doppler shift. Typical results are presented. (orig.)

  16. Laue lens for radiotherapy applications through a focused hard x-ray beam: a feasibility study on requirements and tolerances

    Science.gov (United States)

    Camattari, Riccardo

    2017-09-01

    Focusing a hard x-ray beam would represent an innovative technique for tumour treatment, since such a beam may deliver a dose to a tumour located at a given depth under the skin, sparing the surrounding healthy cells. A detailed study of a focusing system for hard x-ray aimed at radiotherapy is presented here. Such a focusing system, named Laue lens, exploits x-ray diffraction and consists of a series of crystals disposed as concentric rings capable of concentrating a flux of x-rays towards a focusing point. A feasibility study regarding the positioning tolerances of the crystalline optical elements has been carried out. It is shown that a Laue lens can effectively be used in the context of radiotherapy for tumour treatments provided that the mounting errors are below certain values, which are reachable in the modern micromechanics. An extended survey based on an analytical approach and on simulations is presented for precisely estimating all the contributions of each mounting error, analysing their effect on the focal spot of the Laue lens. Finally, a simulation for evaluating the released dose in a water phantom is shown.

  17. Talbot Carpet Simulation for X-ray grating interferometer

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Youngju; Oh, Ohsung; Jeong, Hanseong; Kim, Jeongho; Lee, Seung Wook [Pusan National University, Busan (Korea, Republic of); Kim, Jongyul; Moon, Myungkook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    In this study, Talbot carpet simulator has been developed to visualize the X-ray grating interference patterns in grating interferometer. We have simulated X-ray interference for a variety of simulations and demonstrated a few examples in this summary. Grating interferometer produces interference of X-ray called Talbot pattern with gratings manufactured in micro scale. Talbot pattern is self-images of phase grating which develops interference as beam splitter that is one of gratings consisted of interferometer. As the other gratings, there are source grating makes coherence and analyze grating is used to analyze interference onto detector. Talbot carpet has been studied as the beam behavior which is distinguished with common X-ray imaging systems. It is helpful to understand grating interferometer and possible to expect beams' oscillation for designing theoretically. We confirm pattern has periodicity produced by interference after pi and pi/2 phase grating and changes in the perpendicular direction to entrance face according to phase objects.

  18. X-ray streak camera for observation of tightly pinched relativistic electron beams

    International Nuclear Information System (INIS)

    Johnson, D.J.

    1977-01-01

    A pinhole camera is coupled with a Pilot-B scintillator and image-intensified TRW streak camera to study pinched electron beam profiles via observation of anode target bremsstrahlung. Streak intensification is achieved with an EMI image intensifier operated at a gain of up to 10 6 which allows optimizing the pinhole configuration so that resolution is simultaneously limited by photon-counting statistics and pinhole geometry. The pinhole used is one-dimensional and is fabricated by inserting uranium shims with hyperbolic curved edges between two 5-cm-thick lead blocks. The loss of spatial resolution due to the x-ray transmission through the perimeter of the pinhole is calculated and a streak photograph of a Gamble I pinched beam interacting with a brass anode is presented

  19. X-ray Free-electron Lasers

    Energy Technology Data Exchange (ETDEWEB)

    Feldhaus, J.; /DESY; Arthur, J.; Hastings, J.B.; /SLAC

    2007-02-23

    In a free-electron laser (FEL) the lasing medium is a high-energy beam of electrons flying with relativistic speed through a periodic magnetic field. The interaction between the synchrotron radiation that is produced and the electrons in the beam induces a periodic bunching of the electrons, greatly increasing the intensity of radiation produced at a particular wavelength. Depending only on a phase match between the electron energy and the magnetic period, the wavelength of the FEL radiation can be continuously tuned within a wide spectral range. The FEL concept can be adapted to produce radiation wavelengths from millimeters to Angstroms, and can in principle produce hard x-ray beams with unprecedented peak brightness, exceeding that of the brightest synchrotron source by ten orders of magnitude or more. This paper focuses on short-wavelength FELs. It reviews the physics and characteristic properties of single-pass FELs, as well as current technical developments aiming for fully coherent x-ray radiation pulses with pulse durations in the 100 fs to 100 as range. First experimental results at wavelengths around 100 nm and examples of scientific applications planned on the new, emerging x-ray FEL facilities are presented.

  20. Compensating the electron beam energy spread by the natural transverse gradient of laser undulator in all-optical x-ray light sources.

    Science.gov (United States)

    Zhang, Tong; Feng, Chao; Deng, Haixiao; Wang, Dong; Dai, Zhimin; Zhao, Zhentang

    2014-06-02

    All-optical ideas provide a potential to dramatically cut off the size and cost of x-ray light sources to the university-laboratory scale, with the combination of the laser-plasma accelerator and the laser undulator. However, the large longitudinal energy spread of the electron beam from laser-plasma accelerator may hinder the way to high brightness of these all-optical light sources. In this paper, the beam energy spread effect is proposed to be significantly compensated by the natural transverse gradient of a laser undulator when properly transverse-dispersing the electron beam. Theoretical analysis and numerical simulations on conventional laser-Compton scattering sources and high-gain all-optical x-ray free-electron lasers with the electron beams from laser-plasma accelerators are presented.

  1. Effective x-ray attenuation measurements with full field digital mammography

    International Nuclear Information System (INIS)

    Heine, John J.; Behera, Madhusmita

    2006-01-01

    This work shows that effective x-ray attenuation coefficients may be estimated by applying Beer's Law to phantom image data acquired with the General Electric Senographe 2000D full field digital mammography system. Theoretical developments are provided indicating that an approximate form of the Beer's relation holds for polychromatic x-ray beams. The theoretical values were compared with experimentally determined measured values, which were estimated at various detector locations. The measured effective attenuation coefficients are in agreement with those estimated with theoretical developments and numerical integration. The work shows that the measured quantities show little spatial variation. The main ideas are demonstrated with polymethylmethacrylate and breast tissue equivalent phantom imaging experiments. The work suggests that the effective attenuation coefficients may be used as known values for radiometric standardization applications that compensate for the image acquisition influences. The work indicates that it is possible to make quantitative attenuation coefficient measurements from a system designed for clinical purposes

  2. X-ray micro-beam characterization of a small pixel spectroscopic CdTe detector

    Science.gov (United States)

    Veale, M. C.; Bell, S. J.; Seller, P.; Wilson, M. D.; Kachkanov, V.

    2012-07-01

    A small pixel, spectroscopic, CdTe detector has been developed at the Rutherford Appleton Laboratory (RAL) for X-ray imaging applications. The detector consists of 80 × 80 pixels on a 250 μm pitch with 50 μm inter-pixel spacing. Measurements with an 241Am γ-source demonstrated that 96% of all pixels have a FWHM of better than 1 keV while the majority of the remaining pixels have FWHM of less than 4 keV. Using the Diamond Light Source synchrotron, a 10 μm collimated beam of monochromatic 20 keV X-rays has been used to map the spatial variation in the detector response and the effects of charge sharing corrections on detector efficiency and resolution. The mapping measurements revealed the presence of inclusions in the detector and quantified their effect on the spectroscopic resolution of pixels.

  3. Building a graphite calorimetry system for the dosimetry of therapeutic x-ray beams

    Energy Technology Data Exchange (ETDEWEB)

    Kim, In Jung; Kim, Byoung Chul; Kim, Joong Hyun; Chung, Jae Pil; Kim, Hyun Moon; Yi, Chul Young [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2017-06-15

    A graphite calorimetry system was built and tested under irradiation. The noise level of the temperature measurement system was approximately 0.08 mK (peak to peak). The temperature of the core part rose by approximately 8.6 mK at 800 MU (monitor unit) for 6-MV X-ray beams, and it increased as X-ray energy increased. The temperature rise showed less spread when it was normalized to the accumulated charge, as measured by an external monitoring chamber. The radiation energy absorbed by the core part was determined to have values of 0.798 J/μC, 0.389 J/μC, and 0.352 J/μC at 6 MV, 10 MV, and 18 MV, respectively. These values were so consistent among repeated runs that their coefficient of variance was less than 0.15%.

  4. A CMOS active pixel sensor system for laboratory- based x-ray diffraction studies of biological tissue

    International Nuclear Information System (INIS)

    Bohndiek, Sarah E; Cook, Emily J; Arvanitis, Costas D; Olivo, Alessandro; Royle, Gary J; Clark, Andy T; Prydderch, Mark L; Turchetta, Renato; Speller, Robert D

    2008-01-01

    X-ray diffraction studies give material-specific information about biological tissue. Ideally, a large area, low noise, wide dynamic range digital x-ray detector is required for laboratory-based x-ray diffraction studies. The goal of this work is to introduce a novel imaging technology, the CMOS active pixel sensor (APS) that has the potential to fulfil all these requirements, and demonstrate its feasibility for coherent scatter imaging. A prototype CMOS APS has been included in an x-ray diffraction demonstration system. An industrial x-ray source with appropriate beam filtration is used to perform angle dispersive x-ray diffraction (ADXRD). Optimization of the experimental set-up is detailed including collimator options and detector operating parameters. Scatter signatures are measured for 11 different materials, covering three medical applications: breast cancer diagnosis, kidney stone identification and bone mineral density calculations. Scatter signatures are also recorded for three mixed samples of known composition. Results are verified using two independent models for predicting the APS scatter signature: (1) a linear systems model of the APS and (2) a linear superposition integral combining known monochromatic scatter signatures with the input polychromatic spectrum used in this case. Cross validation of experimental, modelled and literature results proves that APS are able to record biologically relevant scatter signatures. Coherent scatter signatures are sensitive to multiple materials present in a sample and provide a means to quantify composition. In the future, production of a bespoke APS imager for x-ray diffraction studies could enable simultaneous collection of the transmitted beam and scattered radiation in a laboratory-based coherent scatter system, making clinical transfer of the technique attainable

  5. Compact energy dispersive X-ray microdiffractometer for diagnosis of neoplastic tissues

    Science.gov (United States)

    Sosa, C.; Malezan, A.; Poletti, M. E.; Perez, R. D.

    2017-08-01

    An energy dispersive X-ray microdiffractometer with capillary optics has been developed for characterizing breast cancer. The employment of low divergence capillary optics helps to reduce the setup size to a few centimeters, while providing a lateral spatial resolution of 100 μm. The system angular calibration and momentum transfer resolution were assessed by a detailed study of a polycrystalline reference material. The performance of the system was tested by means of the analysis of tissue-equivalent samples previously characterized by conventional X-ray diffraction. In addition, a simplified correction model for an appropriate comparison of the diffraction spectra was developed and validated. Finally, the system was employed to evaluate normal and neoplastic human breast samples, in order to determine their X-ray scatter signatures. The initial results indicate that the use of this compact energy dispersive X-ray microdiffractometer combined with a simplified correction procedure is able to provide additional information to breast cancer diagnosis.

  6. Thermal management of next-generation contact-cooled synchrotron x-ray mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Khounsary, A.

    1999-10-29

    In the past decade, several third-generation synchrotrons x-ray sources have been constructed and commissioned around the world. Many of the major problems in the development and design of the optical components capable of handling the extremely high heat loads of the generated x-ray beams have been resolved. It is expected, however, that in the next few years even more powerful x-ray beams will be produced at these facilities, for example, by increasing the particle beam current. In this paper, the design of a next generation of synchrotron x-ray mirrors is discussed. The author shows that the design of contact-cooled mirrors capable of handing x-ray beam heat fluxes in excess of 500 W/mm{sup 2} - or more than three times the present level - is well within reach, and the limiting factor is the thermal stress rather then thermally induced slope error.

  7. Material Discriminated X-Ray CT System by Using New X-Ray Imager with Energy Discriminate Function

    Directory of Open Access Journals (Sweden)

    Toru Aoki

    2008-04-01

    Full Text Available Material discriminated X-ray CT system has been constructed by using conventional X-ray tube (white X-ray source and photon-counting X-ray imager as an application with energy band detection. We have already reported material identify X-ray CT using K-shell edge method elsewhere. In this report the principle of material discrimination was adapted the separation of electron-density and atomic number from attenuation coefficient mapping in X-ray CT reconstructed image in two wavelength X-ray CT method using white X-ray source and energy discriminated X-ray imager by using two monochrome X-ray source method. The measurement phantom was prepared as four kinds material rods (Carbon(C, Iron(Fe, Copper(Cu, Titanium(Ti rods of 3mm-diameter inside an aluminum(Al rod of 20mm-diameter. We could observed material discriminated X-ray CT reconstructed image, however, the discrimination properties were not good than two monochrome X-ray CT method. This results was could be explained because X-ray scattering, beam-hardening and so on based on white X-ray source, which could not observe in two monochrome X-ray CT method. However, since our developed CdTe imager can be detect five energy-bands at the same time, we can use multi-band analysis to decrease the least square error margin. We will be able to obtain more high separation in atomic number mapping in X-ray CT reconstructed image by using this system.

  8. Do we need X-rays?

    International Nuclear Information System (INIS)

    Sadat, Theo

    2004-01-01

    Do we need X-rays? The answer depends on the cost for 25 kGy sterilization, and the cost for 10 kGy decontamination, compared with the costs of other technologies. In the past, the cost of X-ray was compared with that of Cobalt 60, because treatment by pallet was virtually obsessional. It was considered easier to treat in a Contract Service Center even though several Contract Service Centers equipped with 10 MeV high-power accelerators are in operation, and are profitable. Currently small and reliable accelerators are available, which can be inserted into a production line, i.e. instead of treating a product in its shipment carton or on a pallet, the product can be treated as a unit on the production line. In this case there is no need for extra transport, or intermediate storage facilities, and the product is 'just in time'. So we should compare the cost of treatment, taking all these parameters into account (transport, storage, time lapse, etc.) to find out if X-ray treatment could be competitive. The few studies carried out in the past compared X-ray with Cobalt 60, and the economic result was always in favour of Cobalt due to the poor conversion output. This is still valid today, even if we consider very high-power electron beam accelerators. The performance and cost of e-beam in-line, gamma ray and X-ray will be compared

  9. Effects of X-rays spectrum on the dose

    International Nuclear Information System (INIS)

    Rodriguez I, J. L.; Hernandez A, P. L.; Vega C, H. R.; Rivera M, T.

    2015-10-01

    The X-ray equipment for diagnosis comes in different sizes and shapes depending on the scan type to perform. The X-ray spectrum is the energy distribution of the beam photons and consists of a continuous spectrum of photons braking and discrete spectrum due to the characteristic photons. The knowledge of the X-rays spectrum is important to understand like they affect the voltage changes (k Vp), current (m A), time (s) and the type of filter in the interaction mechanisms between X-rays and patient's body, the image receptor or other material that gets in the beam. Across the spectrum can be estimated the absorbed dose in any point of the patient, the quality of the image and the scattered radiation (which is related to the dose received by the equipment operator). The Monte Carlo method was used by MCNP5 code to calculate the spectrum of X-rays that occurs when a monoenergetic electron beam of 250 keV interact with targets of Mo, Rh and W. The spectra were calculated with and without filter, and the values of ambient dose equivalent were estimated, as well as the air kerma. (Author)

  10. Sources of the X-rays Based on Compton Scattering

    International Nuclear Information System (INIS)

    Androsov, V.; Bulyak, E.; Gladkikh, P.; Karnaukhov, I.; Mytsykov, A.; Telegin, Yu.; Shcherbakov, A.; Zelinsky, A.

    2007-01-01

    The principles of the intense X-rays generation by laser beam scattering on a relativistic electron beam are described and description of facilities assigned to produce the X-rays based on Compton scattering is presented. The possibilities of various types of such facilities are estimated and discussed. The source of the X-rays based on a storage ring with low beam energy is described in details and advantages of the sources of such type are discussed.The results of calculation and numerical simulation carried out for laser electron storage ring NESTOR that is under development in NSC KIPT show wide prospects of the accelerator facility of such type

  11. Progress in Development of Kharkov X-Ray Generator Nestor

    CERN Document Server

    Androsov, V; Botman, J I M; Bulyak, V; Dovbnya, A; Drebot, I; Gladkikh, P; Grevtsev, V; Grigorev, Yu; Gvozd, A; Ivashchenko, V; Karnaukhov, I; Kovalyova, N; Kozin, V; Lapshin, V; Lebedev, A; Lyashchenko, V; Markov, V; Mocheshnikov, N; Molodkin, V; Mytsykov, A; Neklyudov, I; Peev, F; Rezaev, A; Shcherbakov, A; Shpak, A; Skirda, V; Skomorovsky, V I; Tatchyn, R; Telegin, Yu P; Trotsenko, V; Zelinsky, A; Zvonarova, O

    2005-01-01

    The sources of the X-rays based on Compton scattering of intense Nd:YAG laser beam on electron beam circulating in a storage ring with beam energy 43 - 225 MeV is under construction in NSC KIPT. In the paper the progress in development and construction of Kharkov X-ray generator NESTOR is presented. The current status of the main facility system design and development are described. New scheme and main parameters of injection system are presented. The facility is going to be in operation in the middle of 2007 and generated X-rays flux is expected to be of about 10(13) phot/s.

  12. Control console for the X-ray room; Consola de control para la sala de rayos X

    Energy Technology Data Exchange (ETDEWEB)

    Garcia H, J.M.; Aguilar B, M.A.; Torres B, M.A

    1998-07-01

    It is presented the design and construction of Control console for the X-ray room of Metrology Center for ionizing radiations at National Institute of Nuclear Research (ININ). This system controls the positioning of 6 different filters for an X-ray beam. Also it controls a shutter which blockades the beam during periods established by user, these periods can be fixed from hours until tenth of second. The shutter opening periods, as well as the X-ray beam filter are establish and monitoring from a Personal computer outside of room. (Author)

  13. Experimental investigations of the dosimetric features of x-ray radiation used in x-ray diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Prostyakova, M A

    1975-10-01

    For radiation hygiene estimates of the extent of the irradiation of various organs and tissues in roentgenological investigations, the quality and quantity of the primary radiation beam and its behaviour in the irradiated medium are assessed. It is shown that the effective energy of x-rays generated at 50-100 kV and with different radiation field dimensions at different depths in a tissue-equivalent irradiated medium is more or less constant, varying within the range 25 to 32 keV. The constancy of effective x-ray energies in a tissue-equivalent medium enables one to use, for different x-ray tube regimes, constant values of the roentgen-rad conversion factor for soft tissue and bone tissue. The investigations confirm the desirability of using high voltages across the x-ray tube in practical x-ray work.

  14. Hard alpha-keratin degradation inside a tissue under high flux X-ray synchrotron micro-beam: a multi-scale time-resolved study.

    Science.gov (United States)

    Leccia, Emilie; Gourrier, Aurélien; Doucet, Jean; Briki, Fatma

    2010-04-01

    X-rays interact strongly with biological organisms. Synchrotron radiation sources deliver very intense X-ray photon fluxes within micro- or submicro cross-section beams, resulting in doses larger than the MGy. The relevance of synchrotron radiation analyses of biological materials is therefore questionable since such doses, million times higher than the ones used in radiotherapy, can cause huge damages in tissues, with regard to not only DNA, but also proteic and lipid organizations. Very few data concerning the effect of very high X-ray doses in tissues are available in the literature. We present here an analysis of the structural phenomena which occur when the model tissue of human hair is irradiated by a synchrotron X-ray micro-beam. The choice of hair is supported by its hierarchical and partially ordered keratin structure which can be analysed inside the tissue by X-ray diffraction. To assess the damages caused by hard X-ray micro-beams (1 microm(2) cross-section), short exposure time scattering SAXS/WAXS patterns have been recorded at beamline ID13 (ESRF) after various irradiation times. Various modifications of the scattering patterns are observed, they provide fine insight of the radiation damages at various hierarchical levels and also unexpectedly provide information about the stability of the various hierarchical structural levels. It appears that the molecular level, i.e. the alpha helices which are stabilized by hydrogen bonds and the alpha-helical coiled coils which are stabilized by hydrophobic interactions, is more sensitive to radiation than the supramolecular architecture of the keratin filament and the filament packing within the keratin associated proteins matrix, which is stabilized by disulphide bonds. (c) 2009 Elsevier Inc. All rights reserved.

  15. Rib necrosis after postoperative irradiation with 6MeV x-ray to breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Asakawa, H; Watarai, J; Otawa, H [Miyagi Prefectural Adult Disease Center, Natori (Japan)

    1975-04-01

    In order to examine quality of rays in radiation injury in the rib by high energy x-ray, radiation injury in the rib was roentgenologically followed up in the subjects that received postoperative irradiation only with 6 MeV x-ray to breast cancer. The subjects consisted of 79 patients with the age of 30 to 78 and were irradiated with 200 rads of 6 MeV x-ray 5 times a week delivered in 5 to 6 weeks postoperatively. Two fields were irradiated in a day and the total dose reached more than 5,000 rads. Roentgenologic follow up for more than 12 months revealed that rib necrosis occurred in 9 (11%) of 79 patients and that there was no relation to the age of patient. The necrosis was most likely to develop in the right second rib 10 to 23 months after the irradiation and the mean was 16 months. To the rib region where necrosis occurred, 1,880 to 2,230 ret were irradiated and the mean was 2,014 ret. There found no relation between the irradiation dose and occurrence of rib necrosis in the extent of 4,000 to 6,000 rads for tumor doses. Radiation injury in the lung was complicated in 8 (89%) of 9 patients with rib necrosis, indicating high incidence.

  16. Breast tissue classification using x-ray scattering measurements and multivariate data analysis

    Science.gov (United States)

    Ryan, Elaine A.; Farquharson, Michael J.

    2007-11-01

    This study utilized two radiation scatter interactions in order to differentiate malignant from non-malignant breast tissue. These two interactions were Compton scatter, used to measure the electron density of the tissues, and coherent scatter to obtain a measure of structure. Measurements of these parameters were made using a laboratory experimental set-up comprising an x-ray tube and HPGe detector. The breast tissue samples investigated comprise five different tissue classifications: adipose, malignancy, fibroadenoma, normal fibrous tissue and tissue that had undergone fibrocystic change. The coherent scatter spectra were analysed using a peak fitting routine, and a technique involving multivariate analysis was used to combine the peak fitted scatter profile spectra and the electron density values into a tissue classification model. The number of variables used in the model was refined by finding the sensitivity and specificity of each model and concentrating on differentiating between two tissues at a time. The best model that was formulated had a sensitivity of 54% and a specificity of 100%.

  17. Breast tissue classification using x-ray scattering measurements and multivariate data analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ryan, Elaine A; Farquharson, Michael J [School of Allied Health Sciences, City University, Charterhouse Square, London EC1M 6PA (United Kingdom)

    2007-11-21

    This study utilized two radiation scatter interactions in order to differentiate malignant from non-malignant breast tissue. These two interactions were Compton scatter, used to measure the electron density of the tissues, and coherent scatter to obtain a measure of structure. Measurements of these parameters were made using a laboratory experimental set-up comprising an x-ray tube and HPGe detector. The breast tissue samples investigated comprise five different tissue classifications: adipose, malignancy, fibroadenoma, normal fibrous tissue and tissue that had undergone fibrocystic change. The coherent scatter spectra were analysed using a peak fitting routine, and a technique involving multivariate analysis was used to combine the peak fitted scatter profile spectra and the electron density values into a tissue classification model. The number of variables used in the model was refined by finding the sensitivity and specificity of each model and concentrating on differentiating between two tissues at a time. The best model that was formulated had a sensitivity of 54% and a specificity of 100%.

  18. Line focus x-ray tubes-a new concept to produce high brilliance x-rays.

    Science.gov (United States)

    Bartzsch, Stefan; Oelfke, Uwe

    2017-10-27

    Currently hard coherent x-ray radiation at high photon fluxes can only be produced with large and expensive radiation sources, such as 3[Formula: see text] generation synchrotrons. Especially in medicine, this limitation prevents various promising developments in imaging and therapy from being translated into clinical practice. Here we present a new concept of highly brilliant x-ray sources, line focus x-ray tubes (LFXTs), which may serve as a powerful and cheap alternative to synchrotrons and a range of other existing technologies. LFXTs employ an extremely thin focal spot and a rapidly rotating target for the electron beam which causes a change in the physical mechanism of target heating, allowing higher electron beam intensities at the focal spot. Monte Carlo simulations and numeric solutions of the heat equation are used to predict the characteristics of the LFXT. In terms of photon flux and coherence length, the performance of the line focus x-ray tube compares with inverse Compton scattering sources. Dose rates of up to 180 Gy [Formula: see text] can be reached in 50 cm distance from the focal spot. The results demonstrate that the line focus tube can serve as a powerful compact source for phase contrast imaging and microbeam radiation therapy. The production of a prototype seems technically feasible.

  19. Dosimetry of x-ray beams: The measure of the problem

    International Nuclear Information System (INIS)

    de Castro, T.M.

    1986-08-01

    This document contains the text of an oral presentation on dosimetry of analytical x-ray equipment presented at the Denver X-Ray Conference. Included are discussions of sources of background radiation, exposure limits from occupational sources, and the relationship of these sources to the high dose source of x-rays found in analytical machines. The mathematical basis of x-ray dosimetry is reviewed in preparation for more detailed notes on personnel dosimetry and the selection of the most appropriate dosimeter for a specific application. The presentation concludes with a discussion common to previous x-ray equipment accidents. 2 refs

  20. Semi-empirical procedures for correcting detector size effect on clinical MV x-ray beam profiles

    International Nuclear Information System (INIS)

    Sahoo, Narayan; Kazi, Abdul M.; Hoffman, Mark

    2008-01-01

    The measured radiation beam profiles need to be corrected for the detector size effect to derive the real profiles. This paper describes two new semi-empirical procedures to determine the real profiles of high-energy x-ray beams by removing the detector size effect from the measured profiles. Measured profiles are corrected by shifting the position of each measurement point by a specific amount determined from available theoretical and experimental knowledge in the literature. The authors developed two procedures to determine the amount of shift. In the first procedure, which employs the published analytical deconvolution procedure of other investigators, the shift is determined from the comparison of the analytical fit of the measured profile and the corresponding analytical real profile derived from the deconvolution of the fitted measured profile and the Gaussian detector response function. In the second procedure, the amount of shift at any measurement point is considered to be proportional to the value of an analytical function related to the second derivative of the real profile at that point. The constant of proportionality and a parameter in the function are obtained from the values of the shifts at the 90%, 80%, 20%, and 10% dose levels, which are experimentally known from the published results of other investigators to be approximately equal to half of the radius of the detector. These procedures were tested by correcting the profiles of 6 and 18 MV x-ray beams measured by three different ionization chambers and a stereotactic field diode detector with 2.75, 2, 1, and 0.3 mm radii of their respective active cylindrical volumes. The corrected profiles measured by different detectors are found to be in close agreement. The detector size corrected penumbra widths also agree with the expected values based on the results of an earlier investigation. Thus, the authors concluded that the proposed procedures are accurate and can be used to derive the real

  1. Simple, compact, high brightness source for x-ray lithography and x-ray radiography

    International Nuclear Information System (INIS)

    Hawryluk, A.M.

    1986-01-01

    A simple, compact, high brightness x-ray source has recently been built. This source utilizes a commercially available, cylindrical geometry electron beam evaporator, which has been modified to enhance the thermal cooling to the anode. Cooling is accomplished by using standard, low-conductivity laboratory water, with an inlet pressure of less than 50 psi, and a flow rate of approx.0.3 gal/min. The anode is an inverted cone geometry for efficient cooling. The x-ray source has a measured sub-millimeter spot size (FWHM). The anode has been operated at 1 KW e-beam power (10 KV, 100 ma). Higher operating levels will be investigated. A variety of different x-ray lines can be obtained by the simple interchange of anodes of different materials. Typical anodes are made from easily machined metals, or materials which are vacuum deposited onto a copper anode. Typically, a few microns of material is sufficient to stop 10 KV electrons without significantly decreasing the thermal conductivity through the anode. The small size and high brightness of this source make it useful for step and repeat exposures over several square centimeter areas, especially in a research laboratory environment. For an aluminum anode, the estimated Al-K x-ray flux at 10 cms from the source is 70 μW/cm 2

  2. X-ray diffraction imaging of material microstructures

    KAUST Repository

    Varga, Laszlo; Varga, Bonbien; Calo, Victor

    2016-01-01

    Various examples are provided for x-ray imaging of the microstructure of materials. In one example, a system for non-destructive material testing includes an x-ray source configured to generate a beam spot on a test item; a grid detector configured

  3. Handbook on simultaneous x-ray and γ-ray ion beam methods for fine particle analysis

    International Nuclear Information System (INIS)

    Cohen, D.D.

    2000-01-01

    Sampling, measurement, characterisation and source appointment of fine atmospheric particles has become increasingly important in recent times. This is due in part to the realisation that the fine particle pollution caused by anthropogenic activities plays a key role in certain aspects of human health, pollution transport and global climate change. This publication discusses accelerator based ion beam analysis (IBA) methods of particle induced X-ray emission (PIXE) and particle induced γ-ray emission (PIGE) as applied to aerosol analysis. These techniques are sensitive, multielemental, mainly non-destructive, require no sample preparation, have short analysis times and can be used to analyse hundreds of filter samples a day in batch processing with minimum operator interaction. The aspects discussed in the publication include: the basics of the techniques; spectrum analysis; system calibration and blank subtraction; quantification; sensitivity; measurement errors

  4. Development on the muonic X-ray analysis for planetary materials

    International Nuclear Information System (INIS)

    Terada, Kentaro

    2017-01-01

    Three-dimensional nondestructive element analysis using muons artificially generated by bombarding carbon nuclei with high-energy protons has become realistic. This paper explained the principle of characteristic X-ray element analysis by means of negative muon beams. Next, as the experiments demonstrating the advantages of negative muon characteristic X-rays using the high-intensity proton accelerator facility (J-PARC MUSE), it explained the following experiments: (1) measurement of the depth profile of negative muon characteristic X-ray intensity of B, C, N, O using four-layer simulated samples, (2) negative muon characteristic X-ray analysis of carbonaceous chondrites meteorite (Murchison and Allende meteorite) samples, and (3) negative muon characteristic X-ray measurement of Murchison meteorite enclosed in a glass tube. It also introduced the negative muon characteristic X-ray analysis of carbonaceous chondrite meteorite sample, Jbilet Winselwan, at MuSIC (Muon Science Innovative muon beam channel) of the Research Center for Nuclear Physics of Osaka University. MuSIC increased the negative muon beam intensity by 50 times and introduced a double strip CdTe detector capable of X-ray imaging, aiming at the practical application of three-dimensional nondestructive element analysis. (A.O.)

  5. Coherent hard x-ray focusing optics and applications

    Energy Technology Data Exchange (ETDEWEB)

    Yun, W.B.; Viccaro, P.J.; Chrzas, J.; Lai, B.

    1991-01-01

    Coherent hard x-ray beams with a flux exceeding 10{sup 9} photons/second with a bandwidth of 0.1% will be provided by the undulator at the third generation synchrotron radiation sources such as APS, ESRF, and Spring-8. The availability of such high flux coherent x-ray beams offers excellent opportunities for extending the coherence-based techniques developed in the visible and soft x-ray part of the electromagnetic spectrum to the hard x-rays. These x-ray techniques (e.g., diffraction limited microfocusing, holography, interferometry, phase contrast imaging and signal enhancement), may offer substantial advantages over non-coherence-based x-ray techniques currently used. For example, the signal enhancement technique may be used to enhance an anomalous x-ray or magnetic x-ray scattering signal by several orders of magnitude. Coherent x-rays can be focused to a very small (diffraction-limited) spot size, thus allowing high spatial resolution microprobes to be constructed. The paper will discuss the feasibility of the extension of some coherence-based techniques to the hard x-ray range and the significant progress that has been made in the development of diffraction-limited focusing optics. Specific experimental results for a transmission Fresnel phase zone plate that can focus 8.2 keV x-rays to a spot size of about 2 microns will be briefly discussed. The comparison of measured focusing efficiency of the zone plate with that calculated will be made. Some specific applications of zone plates as coherent x-ray optics will be discussed. 17 refs., 4 figs.

  6. Nondestructive mapping of chemical composition and structural qualities of group III-nitride nanowires using submicron beam synchrotron-based X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Bonanno, P.L., E-mail: plb2@njit.edu [Georgia Institute of Technology/GTL, UMI 2958 Georgia Tech-CNRS, 57070 Metz (France); Gautier, S. [LMOPS + UMI: Laboratoire Matériaux Optiques, Photonique et micro-nano Systèmes, UMR CNRS 7132, Université de Metz et SUPELEC, 2 rue E. Belin, 57070 Metz, France, UMI 2958 Georgia Tech-CNRS, 57070 Metz (France); Gmili, Y.El.; Moudakir, T. [UMI 2958 Georgia Tech-CNRS, 57070 Metz (France); Sirenko, A.A. [Department of Physics, New Jersey Institute of Technology, Newark, NJ 07102 (United States); Kazimirov, A. [Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, NY 14853 (United States); Cai, Z.-H. [Advanced Photon Source, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Martin, J. [LMOPS + UMI: Laboratoire Matériaux Optiques, Photonique et micro-nano Systèmes, UMR CNRS 7132, Université de Metz et SUPELEC, 2 rue E. Belin, 57070 Metz, France, UMI 2958 Georgia Tech-CNRS, 57070 Metz (France); Goh, W.H. [Georgia Institute of Technology/GTL, UMI 2958 Georgia Tech-CNRS, 57070 Metz (France); Martinez, A.; Ramdane, A.; Le Gratiet, L. [Laboratoire de Photonique et de Nanostructures, UPR CNRS 20, Route de Nozay, 91460 Marcoussis (France); Maloufi, N. [Laboratoire d' Etude des Textures et Application aux Matériaux UMR CNRS 7078 Ile du Saulcy 57045 METZ cedex 1 (France); Assouar, M.B. [Laboratoire de Physique des Milieux Ionisés et Applications, Nancy University, CNRS, BP 239, F-54506 Vandoeuvre-lès-Nancy Cédex (France); Ougazzaden, A. [Georgia Institute of Technology/GTL, UMI 2958 Georgia Tech-CNRS, 57070 Metz (France)

    2013-08-31

    Submicron beam synchrotron-based X-ray diffraction (XRD) techniques have been developed and used to accurately and nondestructively map chemical composition and material quality of selectively grown group III-nitride nanowires. GaN, AlGaN, and InGaN multi-quantum-well nanowires have been selectively grown on lattice matched and mismatched substrates, and the challenges associated with obtaining and interpreting submicron beam XRD results are addressed and solved. Nanoscale cathodoluminescence is used to examine exciton behavior, and energy-dispersive X-ray spectroscopy is used to verify chemical composition. Scanning transmission electron microscopy is later used to paint a more complete picture. The advantages of submicron beam XRD over other techniques are discussed in the context of this challenging material system. - Highlights: ► We used nano selective area growth to create nanowires of GaN, AlGaN and InGaN/GaN. ► We characterized them by synchrotron-based submicron beam X-ray diffraction (XRD). ► This technique accurately determined chemical and crystallographic properties. ► Challenges of XRD are addressed in the context of this challenging material system. ► Advantages of XRD over other characterization methods are discussed.

  7. MeV single-ion beam irradiation of mammalian cells using the Surrey vertical nanobeam, compared with broad proton beam and X-ray irradiations

    Energy Technology Data Exchange (ETDEWEB)

    Prakrajang, K. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Faculty of Science, Maejo University, Chiang Mai 50290 (Thailand); Jeynes, J.C.G.; Merchant, M.J.; Kirkby, K.; Kirkby, N. [Surrey Ion Beam Center, Faculty of Engineering and Physical Science, University of Surrey, Guildford Surrey, GU2 7XH (United Kingdom); Thopan, P. [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Yu, L.D., E-mail: yuld@fnrf.science.cmu.ac.th [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thailand Center of Excellence in Physics, Commission on Higher Education, 328 Si Ayutthaya Road, Bangkok 10400 (Thailand)

    2013-07-15

    Highlights: •Recently completed nanobeam at the Surrey Ion Beam Centre was used. •3.8-MeV single and broad proton beams irradiated Chinese hamster cells. •Cell survival curves were measured and compared with 300-kV X-ray irradiation. •Single ion irradiation had a lower survival part at ultra-low dose. •It implies hypersensitivity, bystander effect and cell cycle phase of cell death. -- Abstract: As a part of a systematic study on mechanisms involved in physical cancer therapies, this work investigated response of mammalian cells to ultra-low-dose ion beam irradiation. The ion beam irradiation was performed using the recently completed nanobeam facility at the Surrey Ion Beam Centre. A scanning focused vertical ion nano-beam was applied to irradiate Chinese hamster V79 cells. The V79 cells were irradiated in two different beam modes, namely, focused single ion beam and defocused scanning broad ion beam of 3.8-MeV protons. The single ion beam was capable of irradiating a single cell with a precisely controlled number of the ions to extremely low doses. After irradiation and cell incubation, the number of surviving colonies as a function of the number of the irradiating ions was measured for the cell survival fraction curve. A lower survival for the single ion beam irradiation than that of the broad beam case implied the hypersensitivity and bystander effect. The ion-beam-induced cell survival curves were compared with that from 300-kV X-ray irradiation. Theoretical studies indicated that the cell death in single ion irradiation mainly occurred in the cell cycle phases of cell division and intervals between the cell division and the DNA replication. The success in the experiment demonstrated the Surrey vertical nanobeam successfully completed.

  8. Production of X-rays by inverse Compton effect

    International Nuclear Information System (INIS)

    Mainardi, R.T.

    2005-01-01

    X-rays and gamma rays of high energy values can be produced by the scattering of low energy photons with high energy electrons, being this a process controlled by the Compton scattering. If a laser beam is used, the x-ray beam inherits the properties of intensity, monochromaticity and collimation from the laser. In this work we analyze the generation of intense x-ray beams of energies between 10 and 100 KeV to be used in a wide range of applications where a high intensity and high degrees of monochromaticity and polarization are important properties to improve image reduce doses and improve radiation treatments. To this purpose we evaluated, using relativistic kinematics the scattered beam properties in terms of the scattering angle. This arrangement is being considered in several worldwide laboratories as an alternative to synchrotron radiation and is referred to as 'table top synchrotron radiation', since it cost of installation is orders of magnitude smaller than a 'synchrotron radiation source'. The radiation beam might exhibit non-linear properties in its interaction with matter, in a similar way as a laser beam and we will investigate how to calibrate and evaluate TLD dosemeters properties, both in low and high intensity fields either mono or polyenergetic in wide spectral energy ranges. (Author)

  9. Limited-angle x-ray luminescence tomography: methodology and feasibility study

    International Nuclear Information System (INIS)

    Carpenter, C M; Pratx, G; Sun, C; Xing, L

    2011-01-01

    X-ray luminescence tomography (XLT) has recently been proposed as a new imaging modality for biological imaging applications. This modality utilizes phosphor nanoparticles which luminesce near-infrared light when excited by x-ray photons. The advantages of this modality are that it uniquely combines the high sensitivity of radioluminescent nanoparticles and the high spatial localization of collimated x-ray beams. Currently, XLT has been demonstrated using x-ray spatial encoding to resolve the imaging volume. However, there are applications where the x-ray excitation may be limited by geometry, where increased temporal resolution is desired, or where a lower dose is mandatory. This paper extends the utility of XLT to meet these requirements by incorporating a photon propagation model into the reconstruction algorithm in an x-ray limited-angle (LA) geometry. This enables such applications as image-guided surgery, where the ability to resolve lesions at depths of several centimeters can be the key to successful resection. The hybrid x-ray/diffuse optical model is first formulated and then demonstrated in a breast-sized phantom, simulating a breast lumpectomy geometry. Both numerical and experimental phantoms are tested, with lesion-simulating objects of various sizes and depths. Results show localization accuracy with median error of 2.2 mm, or 4% of object depth, for small 2-14 mm diameter lesions positioned from 1 to 4.5 cm in depth. This compares favorably with fluorescence optical imaging, which is not able to resolve such small objects at this depth. The recovered lesion size has lower size bias in the x-ray excitation direction than the optical direction, which is expected due to the increased optical scatter. However, the technique is shown to be quite invariant in recovered size with respect to depth, as the standard deviation is less than 2.5 mm. Sensitivity is a function of dose; radiological doses are found to provide sufficient recovery for μg ml -1

  10. Automated marker tracking using noisy X-ray images degraded by the treatment beam

    Energy Technology Data Exchange (ETDEWEB)

    Wisotzky, E. [Fraunhofer Institute for Production Systems and Design Technology (IPK), Berlin (Germany); German Cancer Research Center (DKFZ), Heidelberg (Germany); Fast, M.F.; Nill, S. [The Royal Marsden NHS Foundation Trust, London (United Kingdom). Joint Dept. of Physics; Oelfke, U. [The Royal Marsden NHS Foundation Trust, London (United Kingdom). Joint Dept. of Physics; German Cancer Research Center (DKFZ), Heidelberg (Germany)

    2015-09-01

    This study demonstrates the feasibility of automated marker tracking for the real-time detection of intrafractional target motion using noisy kilovoltage (kV) X-ray images degraded by the megavoltage (MV) treatment beam. The authors previously introduced the in-line imaging geometry, in which the flat-panel detector (FPD) is mounted directly underneath the treatment head of the linear accelerator. They found that the 121 kVp image quality was severely compromised by the 6 MV beam passing through the FPD at the same time. Specific MV-induced artefacts present a considerable challenge for automated marker detection algorithms. For this study, the authors developed a new imaging geometry by re-positioning the FPD and the X-ray tube. This improved the contrast-to-noise-ratio between 40% and 72% at the 1.2 mAs/image exposure setting. The increase in image quality clearly facilitates the quick and stable detection of motion with the aid of a template matching algorithm. The setup was tested with an anthropomorphic lung phantom (including an artificial lung tumour). In the tumour one or three Calypso {sup registered} beacons were embedded to achieve better contrast during MV radiation. For a single beacon, image acquisition and automated marker detection typically took around 76±6 ms. The success rate was found to be highly dependent on imaging dose and gantry angle. To eliminate possible false detections, the authors implemented a training phase prior to treatment beam irradiation and also introduced speed limits for motion between subsequent images.

  11. Automated marker tracking using noisy X-ray images degraded by the treatment beam

    International Nuclear Information System (INIS)

    Wisotzky, E.; Fast, M.F.; Nill, S.

    2015-01-01

    This study demonstrates the feasibility of automated marker tracking for the real-time detection of intrafractional target motion using noisy kilovoltage (kV) X-ray images degraded by the megavoltage (MV) treatment beam. The authors previously introduced the in-line imaging geometry, in which the flat-panel detector (FPD) is mounted directly underneath the treatment head of the linear accelerator. They found that the 121 kVp image quality was severely compromised by the 6 MV beam passing through the FPD at the same time. Specific MV-induced artefacts present a considerable challenge for automated marker detection algorithms. For this study, the authors developed a new imaging geometry by re-positioning the FPD and the X-ray tube. This improved the contrast-to-noise-ratio between 40% and 72% at the 1.2 mAs/image exposure setting. The increase in image quality clearly facilitates the quick and stable detection of motion with the aid of a template matching algorithm. The setup was tested with an anthropomorphic lung phantom (including an artificial lung tumour). In the tumour one or three Calypso registered beacons were embedded to achieve better contrast during MV radiation. For a single beacon, image acquisition and automated marker detection typically took around 76±6 ms. The success rate was found to be highly dependent on imaging dose and gantry angle. To eliminate possible false detections, the authors implemented a training phase prior to treatment beam irradiation and also introduced speed limits for motion between subsequent images.

  12. Evaluation device of diagnostic X-ray beam

    International Nuclear Information System (INIS)

    Pela, Carlos Alberto; Paula, Eldereis de; Bruco, Jose Luiz; Ghilardi Netto, Thomaz

    1996-01-01

    A device developed to determine the physical parameters useful to the evaluation of both dental and medical X-ray equipment is presented. Nine detectors connected each one to a signal amplifier are used. The amplifiers output has being connected to an analog to digital interface plugged in a PC-AT microcomputer. The X-ray pass through filters before reaching the detectors. The data collected by microcomputer are used to calculate the kVp and other factors as total tube filtration, waveform, half-value layer, exposure rate and exposure time

  13. Dedicated breast CT: radiation dose for circle-plus-line trajectory

    International Nuclear Information System (INIS)

    Vedantham, Srinivasan; Shi, Linxi; Karellas, Andrew; Noo, Frederic

    2012-01-01

    Purpose: Dedicated breast CT prototypes used in clinical investigations utilize single circular source trajectory and cone-beam geometry with flat-panel detectors that do not satisfy data-sufficiency conditions and could lead to cone beam artifacts. Hence, this work investigated the glandular dose characteristics of a circle-plus-line trajectory that fulfills data-sufficiency conditions for image reconstruction in dedicated breast CT. Methods: Monte Carlo-based computer simulations were performed using the GEANT4 toolkit and was validated with previously reported normalized glandular dose coefficients for one prototype breast CT system. Upon validation, Monte Carlo simulations were performed to determine the normalized glandular dose coefficients as a function of x-ray source position along the line scan. The source-to-axis of rotation distance and the source-to-detector distance were maintained constant at 65 and 100 cm, respectively, in all simulations. The ratio of the normalized glandular dose coefficient at each source position along the line scan to that for the circular scan, defined as relative normalized glandular dose coefficient (RD g N), was studied by varying the diameter of the breast at the chest wall, chest-wall to nipple distance, skin thickness, x-ray beam energy, and glandular fraction of the breast. Results: The RD g N metric when stated as a function of source position along the line scan, relative to the maximum length of line scan needed for data sufficiency, was found to be minimally dependent on breast diameter, chest-wall to nipple distance, skin thickness, glandular fraction, and x-ray photon energy. This observation facilitates easy estimation of the average glandular dose of the line scan. Polynomial fit equations for computing the RD g N and hence the average glandular dose are provided. Conclusions: For a breast CT system that acquires 300-500 projections over 2π for the circular scan, the addition of a line trajectory with equal

  14. Epoxy replication for Wolter x-ray microscope fabrication

    International Nuclear Information System (INIS)

    Priedhorsky, W.

    1981-01-01

    An epoxy replica of a test piece designed to simulate a Wolter x-ray microscope geometry showed no loss of x-ray reflectivity or resolution, compared to the original. The test piece was a diamond-turned cone with 1.5 0 half angle. A flat was fly-cut on one side, then super- and conventionally polished. The replica was separated at the 1.5 0 -draft angle, simulating a shallow angle Wolter microscope geometry. A test with 8.34 A x rays at 0.9 0 grazing angle showed a reflectivity of 67% for the replica flat surface, and 70% for the original. No spread of the reflected beam was observed with a 20-arc second wide test beam. This test verifies the epoxy replication technique for production of Wolter x-ray microscopes

  15. Building a Graphite Calorimetry System for the Dosimetry of Therapeutic X-ray Beams

    Directory of Open Access Journals (Sweden)

    In Jung Kim

    2017-06-01

    Full Text Available A graphite calorimetry system was built and tested under irradiation. The noise level of the temperature measurement system was approximately 0.08 mK (peak to peak. The temperature of the core part rose by approximately 8.6 mK at 800 MU (monitor unit for 6-MV X-ray beams, and it increased as X-ray energy increased. The temperature rise showed less spread when it was normalized to the accumulated charge, as measured by an external monitoring chamber. The radiation energy absorbed by the core part was determined to have values of 0.798 J/μC, 0.389 J/μC, and 0.352 J/μC at 6 MV, 10 MV, and 18 MV, respectively. These values were so consistent among repeated runs that their coefficient of variance was less than 0.15%.

  16. Advances in thin film diffraction instrumentation by X-ray optics

    International Nuclear Information System (INIS)

    Haase, A.

    1996-01-01

    The structural characterisation of thin films requires a parallel X-ray beam of high intensity. Parallel beam geometry is commonly used in high resolution and single crystal experiments, but also in the field of X-ray diffraction for polycrystalline material (e.g. in phase, texture and stress analysis). For grazing incidence diffraction (GID), the use of small slits on the primary side and of long soller slits with a flat monochromator on the secondary side is standard. New optical elements have been introduced with polychromatic or monochromatic radiation. By means of different applications the results are compared with those of classical beam optics. X-ray fiber optics utilize total external reflection of X-rays on smooth surfaces. Effects of monochromatization are presented. In many fields of application, fiber optics may replace conventional collimators. The use of primary and secondary channel cut crystals can also produce a high parallel monochromatic X-ray beam. A parabolically bent graded multilayer produces a monochromatic parallel beam of high intensity. Compared with classical Bragg-Brentano (focussing) geometry, excellent results have been obtained, especially for samples with an irregular shape. In combination with a channel cut monochromator there is a substantial gain in intensity leading to an increase of the dynamic intensity range of rocking curves

  17. Advances in thin film diffraction instrumentation by X-ray optics

    Energy Technology Data Exchange (ETDEWEB)

    Haase, A [Rich. Seifert and Co., Analytical X-ray Systems, Ahrensburg (Germany)

    1996-09-01

    The structural characterisation of thin films requires a parallel X-ray beam of high intensity. Parallel beam geometry is commonly used in high resolution and single crystal experiments, but also in the field of X-ray diffraction for polycrystalline material (e.g. in phase, texture and stress analysis). For grazing incidence diffraction (GID), the use of small slits on the primary side and of long soller slits with a flat monochromator on the secondary side is standard. New optical elements have been introduced with polychromatic or monochromatic radiation. By means of different applications the results are compared with those of classical beam optics. X-ray fiber optics utilize total external reflection of X-rays on smooth surfaces. Effects of monochromatization are presented. In many fields of application, fiber optics may replace conventional collimators. The use of primary and secondary channel cut crystals can also produce a high parallel monochromatic X-ray beam. A parabolically bent graded multilayer produces a monochromatic parallel beam of high intensity. Compared with classical Bragg-Brentano (focussing) geometry, excellent results have been obtained, especially for samples with an irregular shape. In combination with a channel cut monochromator there is a substantial gain in intensity leading to an increase of the dynamic intensity range of rocking curves.

  18. Progress in Development of Kharkov X-Ray Generator Nestor

    Energy Technology Data Exchange (ETDEWEB)

    Androsov, V.; Bulyak, V.; Dovbnya, A.; Drebot, I.; Gladkikh, P.; Grevtsev, V.; Grigorev, Yu.; Gvozd, A.; Ivashchenko, V.; Karnaukhov, I.; Kovalyova, N.; Kozin, V.; Lapshin, V.; Lyashchenko, V.; Markov, V.; Mocheshnikov, N.; Mytsykov, A.; Neklyudov, I.; Peev, F.; Rezaev, A.; Shcherbakov, A.; /Kharkov, KIPT /SLAC, SSRL /Eindhoven, Tech. U.

    2005-09-14

    The sources of the X-rays based on Compton scattering of intense Nd:YAG laser beam on electron beam circulating in a storage ring with beam energy 43-225 MeV is under construction in NSC KIPT. In the paper the progress in development and construction of Kharkov X-ray generator NESTOR is presented. The current status of the main facility system design and development are described. New scheme and main parameters of injection system are presented. The status of power supply system and control system is described. The facility is going to be in operation in the middle of 2007 and generated X-rays flux is expected to be of about 10{sup 13} phot/s.

  19. Soft x-ray streak cameras

    International Nuclear Information System (INIS)

    Stradling, G.L.

    1988-01-01

    This paper is a discussion of the development and of the current state of the art in picosecond soft x-ray streak camera technology. Accomplishments from a number of institutions are discussed. X-ray streak cameras vary from standard visible streak camera designs in the use of an x-ray transmitting window and an x-ray sensitive photocathode. The spectral sensitivity range of these instruments includes portions of the near UV and extends from the subkilovolt x- ray region to several tens of kilovolts. Attendant challenges encountered in the design and use of x-ray streak cameras include the accommodation of high-voltage and vacuum requirements, as well as manipulation of a photocathode structure which is often fragile. The x-ray transmitting window is generally too fragile to withstand atmospheric pressure, necessitating active vacuum pumping and a vacuum line of sight to the x-ray signal source. Because of the difficulty of manipulating x-ray beams with conventional optics, as is done with visible light, the size of the photocathode sensing area, access to the front of the tube, the ability to insert the streak tube into a vacuum chamber and the capability to trigger the sweep with very short internal delay times are issues uniquely relevant to x-ray streak camera use. The physics of electron imaging may place more stringent limitations on the temporal and spatial resolution obtainable with x-ray photocathodes than with the visible counterpart. Other issues which are common to the entire streak camera community also concern the x-ray streak camera users and manufacturers

  20. Adaptive x-ray threat detection using sequential hypotheses testing with fan-beam experimental data (Conference Presentation)

    Science.gov (United States)

    Thamvichai, Ratchaneekorn; Huang, Liang-Chih; Ashok, Amit; Gong, Qian; Coccarelli, David; Greenberg, Joel A.; Gehm, Michael E.; Neifeld, Mark A.

    2017-05-01

    We employ an adaptive measurement system, based on sequential hypotheses testing (SHT) framework, for detecting material-based threats using experimental data acquired on an X-ray experimental testbed system. This testbed employs 45-degree fan-beam geometry and 15 views over a 180-degree span to generate energy sensitive X-ray projection data. Using this testbed system, we acquire multiple view projection data for 200 bags. We consider an adaptive measurement design where the X-ray projection measurements are acquired in a sequential manner and the adaptation occurs through the choice of the optimal "next" source/view system parameter. Our analysis of such an adaptive measurement design using the experimental data demonstrates a 3x-7x reduction in the probability of error relative to a static measurement design. Here the static measurement design refers to the operational system baseline that corresponds to a sequential measurement using all the available sources/views. We also show that by using adaptive measurements it is possible to reduce the number of sources/views by nearly 50% compared a system that relies on static measurements.