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Sample records for bastiene vidmantas gurklys

  1. bastien Lechevalier (editor), The Great Transformation of Japanese Capitalism. London: Routledge, 2014. 240 pp

    DEFF Research Database (Denmark)

    Kravtsova, Victoria

    2015-01-01

    Book review of: Sébastien Lechevalier (editor), The Great Transformation of Japanese Capitalism. London: Routledge, 2014.......Book review of: Sébastien Lechevalier (editor), The Great Transformation of Japanese Capitalism. London: Routledge, 2014....

  2. The McGurk Illusion in the Oddity Task

    DEFF Research Database (Denmark)

    Andersen, Tobias

    2010-01-01

    Despite many studies of audiovisual integration in speech perception very few studies have addressed the issue of cross- modal response bias. Using synthetic acoustic speech, the current study demonstrates the McGurk illusion in the oddity task which is not prone to cross-modal response bias...

  3. An ordinal model of the McGurk illusion

    DEFF Research Database (Denmark)

    Andersen, Tobias

    2011-01-01

    an ordinal model, in which the response categories are ordered cyclically, that can account for the McGurk illusion. We compare this model to the Fuzzy Logical Model of Perception (FLMP), which is not an ordinal model, based on an original data set. While the FLMP fitted the data better than the ordinal...

  4. An ordinal model of the McGurk illusion

    DEFF Research Database (Denmark)

    Andersen, Tobias

    2011-01-01

    Audiovisual information is integrated in speech perception. One manifestation of this is the McGurk illusion in which watching the articulating face alters the auditory phonetic percept. Understanding this phenomenon fully requires a computational model with predictive power. Here, we describe...... model it also employed 30 free parameters where the ordinal model needed only 14. Testing the predictive power of the models using a form of cross-validation we found that, although both models performed rather poorly, the ordinal model performed better than the FLMP. Based on these findings we suggest...

  5. Face configuration affects speech perception: Evidence from a McGurk mismatch negativity study

    DEFF Research Database (Denmark)

    Eskelund, Kasper; MacDonald, Ewen; Andersen, Tobias

    2015-01-01

    We perceive identity, expression and speech from faces. While perception of identity and expression depends crucially on the configuration of facial features it is less clear whether this holds for visual speech perception. Facial configuration is poorly perceived for upside-down faces...... the face is upright indicating that facial configuration can be important for visual speech perception. This effect can propagate to auditory speech perception through audiovisual integration so that Thatcherization disrupts the McGurk illusion in which visual speech perception alters perception...... perception due to the McGurk illusion without any change in the acoustic stimulus. We found that Thatcherization disrupted a strong McGurk illusion and a correspondingly strong McGurk-MMN only for upright faces. This confirms that facial configuration can be important for audiovisual speech perception...

  6. Mouth reversal extinguishes mismatch negativity induced by the McGurk illusion

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Andersen, Tobias

    2013-01-01

    The sight of articulatory mouth movements (visual speech) influences auditory speech perception. This is demonstrated by the McGurk illusion in which incongruent visual speech alters the auditory phonetic percept. In behavioral studies, reversal of the vertical mouth direction has been reported...... cortex. Mismatch Negativity (MMN) is a component in the auditory Event-Related Potential (ERP) that is elicited by a change in the auditory percept. It has been shown that the McGurk illusion can induce a MMN. We conducted an experiment in which the MMN could be elicited by the McGurk illusion induced...... by visual speech with either upright (unaltered) or vertically reversed mouth area. In a preliminary analysis, we found a Mismatch Negativity component induced by the McGurk illusion for 6 of 17 participants at electrode Cz when the mouth area was upright. In comparison, these participants produced...

  7. Early and late beta-band power reflect audiovisual perception in the McGurk illusion.

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    Roa Romero, Yadira; Senkowski, Daniel; Keil, Julian

    2015-04-01

    The McGurk illusion is a prominent example of audiovisual speech perception and the influence that visual stimuli can have on auditory perception. In this illusion, a visual speech stimulus influences the perception of an incongruent auditory stimulus, resulting in a fused novel percept. In this high-density electroencephalography (EEG) study, we were interested in the neural signatures of the subjective percept of the McGurk illusion as a phenomenon of speech-specific multisensory integration. Therefore, we examined the role of cortical oscillations and event-related responses in the perception of congruent and incongruent audiovisual speech. We compared the cortical activity elicited by objectively congruent syllables with incongruent audiovisual stimuli. Importantly, the latter elicited a subjectively congruent percept: the McGurk illusion. We found that early event-related responses (N1) to audiovisual stimuli were reduced during the perception of the McGurk illusion compared with congruent stimuli. Most interestingly, our study showed a stronger poststimulus suppression of beta-band power (13-30 Hz) at short (0-500 ms) and long (500-800 ms) latencies during the perception of the McGurk illusion compared with congruent stimuli. Our study demonstrates that auditory perception is influenced by visual context and that the subsequent formation of a McGurk illusion requires stronger audiovisual integration even at early processing stages. Our results provide evidence that beta-band suppression at early stages reflects stronger stimulus processing in the McGurk illusion. Moreover, stronger late beta-band suppression in McGurk illusion indicates the resolution of incongruent physical audiovisual input and the formation of a coherent, illusory multisensory percept.

  8. Alpha-band oscillations reflect altered multisensory processing of the McGurk illusion in schizophrenia

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    Yadira eRoa Romero

    2016-02-01

    Full Text Available The formation of coherent multisensory percepts requires integration of stimuli across the multiple senses. Patients with schizophrenia (ScZ often experience a loss of coherent perception and hence, they might also show dysfunctional multisensory processing. In this high-density electroencephalography study we investigated the neural signatures of the McGurk illusion, as a phenomenon of speech-specific multisensory processing. In the McGurk illusion lip movements are paired with incongruent auditory syllables, which can induce a fused percept. In ScZ patients and healthy controls we compared neural oscillations and event-related potentials (ERPs to congruent audiovisual speech stimuli and McGurk illusion trials, where a visual /ga/ and an auditory /pa/ was often perceived as /ka/. There were no significant group differences in illusion rates. However, we found larger short latency ERPs to McGurk illusion compared with congruent trials in controls, whereas they were reduced in ScZ patients, indicating an early audiovisual processing deficit. Moreover, we observed stronger suppression of medio-central alpha-band power (8-10 Hz, 550-700 ms in response to McGurk illusion compared with control trials in the control group. The reversed pattern was found in SCZ patients. Within groups, alpha-band suppression was negatively correlated with the McGurk illusion rate in ScZ patients, while the correlation tended to be positive in controls. The topography of alpha-band effects suggests an involvement of auditory and/or frontal structures. Our study suggests that early ERPs and later alpha-band oscillations reflect abnormal multisensory processing of the McGurk illusion in schizophrenia.

  9. Distinct cortical locations for integration of audiovisual speech and the McGurk effect

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    Laura C. Erickson

    2014-06-01

    Full Text Available Audiovisual (AV speech integration is often studied using the McGurk effect, where the combination of specific incongruent auditory and visual speech cues produces the perception of a third illusory speech percept. Recently, several studies have implicated the posterior superior temporal sulcus (pSTS in the McGurk effect; however, the exact roles of the pSTS and other brain areas in correcting differing AV sensory inputs remain unclear. Using functional magnetic resonance imaging (fMRI in ten participants, we aimed to isolate brain areas specifically involved in processing congruent AV speech and the McGurk effect. Speech stimuli were composed of sounds and/or videos of consonant-vowel tokens resulting in four stimulus classes: congruent AV speech (AVCong, incongruent AV speech resulting in the McGurk effect (AVMcGurk, acoustic-only speech (AO, and visual-only speech (VO. In group- and single-subject-analyses, left pSTS exhibited significantly greater fMRI signal for congruent AV speech (i.e., AVCong trials than for both AO and VO trials. Right superior temporal gyrus, medial prefrontal cortex, and cerebellum were also identified. For McGurk speech (i.e., AVMcGurk trials, two clusters in the left posterior superior temporal gyrus (pSTG, just posterior to Heschl’s gyrus or on its border, exhibited greater fMRI signal than both AO and VO trials. We propose that while some brain areas, such as left pSTS, may be more critical for the integration of AV speech, other areas, such as left pSTG, may generate the corrected or merged percept arising from conflicting auditory and visual cues (i.e., as in the McGurk effect. These findings are consistent with the concept that posterior superior temporal areas represent part of a dorsal auditory stream, which is involved in multisensory integration, sensorimotor control, and optimal state estimation (Rauschecker and Scott, 2009.

  10. Psychophysics of the McGurk and Other Audiovisual Speech Integration Effects

    Science.gov (United States)

    Jiang, Jintao; Bernstein, Lynne E.

    2011-01-01

    When the auditory and visual components of spoken audiovisual nonsense syllables are mismatched, perceivers produce four different types of perceptual responses, auditory correct, visual correct, fusion (the so-called "McGurk effect"), and combination (i.e., two consonants are reported). Here, quantitative measures were developed to account for…

  11. Psychophysics of the McGurk and Other Audiovisual Speech Integration Effects

    Science.gov (United States)

    Jiang, Jintao; Bernstein, Lynne E.

    2011-01-01

    When the auditory and visual components of spoken audiovisual nonsense syllables are mismatched, perceivers produce four different types of perceptual responses, auditory correct, visual correct, fusion (the so-called "McGurk effect"), and combination (i.e., two consonants are reported). Here, quantitative measures were developed to account for…

  12. Audiovisual perception in adults with amblyopia: a study using the McGurk effect.

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    Narinesingh, Cindy; Wan, Michael; Goltz, Herbert C; Chandrakumar, Manokaraananthan; Wong, Agnes M F

    2014-04-24

    The effects on multisensory integration have rarely been examined in amblyopia. The McGurk effect is a well-established audiovisual illusion that is manifested when an auditory phoneme is presented concurrently with an incongruent visual phoneme. Visually healthy viewers will hear a phoneme that does not match the actual auditory stimulus, having been perceptually influenced by the visual phoneme. This study examines audiovisual integration in adults with amblyopia. Twenty-two subjects with amblyopia and 25 visually healthy controls participated. Participants viewed videos of combinations of visual and auditory phonemes, and were asked to report what they heard. Some videos had congruent video and audio (control), whereas others had incongruent video and audio (McGurk). The McGurk effect is strongest when the visual phoneme dominates over the audio phoneme, resulting in low auditory accuracy on the task. Adults with amblyopia demonstrated a weaker McGurk effect than visually healthy controls (P = 0.01). The difference was greatest when viewing monocularly with the amblyopic eye, and it was also evident when viewing binocularly or monocularly with the fellow eye. No correlations were found between the strength of the McGurk effect and either visual acuity or stereoacuity in subjects with amblyopia. Subjects with amblyopia and controls showed a similar response pattern to different speakers and syllables, and subjects with amblyopia consistently demonstrated a weaker effect than controls. Abnormal visual experience early in life can have negative consequences for audiovisual integration that persists into adulthood in people with amblyopia. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  13. Developmental Trajectory of McGurk Effect Susceptibility in Children and Adults With Amblyopia.

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    Narinesingh, Cindy; Goltz, Herbert C; Raashid, Rana Arham; Wong, Agnes M F

    2015-03-05

    The McGurk effect is an audiovisual illusion that involves the concurrent presentation of a phoneme (auditory syllable) and an incongruent viseme (visual syllable). Adults with amblyopia show less susceptibility to this illusion than visually normal controls, even when viewing binocularly. The present study investigated the developmental trajectory of McGurk effect susceptibility in adults, older children (10-17 years), and younger children (4-9 years) with amblyopia. A total of 62 participants with amblyopia (22 adults, 12 older children, 28 younger children) and 66 visually normal controls (25 adults, 17 older children, 24 younger children) viewed videos that combined phonemes and visemes, and were asked to report what they heard. Videos with congruent (auditory and visual matching) and incongruent (auditory and visual not matching) stimuli were presented. Incorrect responses on incongruent trials correspond to high McGurk effect susceptibility, indicating that the viseme influenced the phoneme. Participants with amblyopia (28.0% ± 3.3%) demonstrated a less consistent McGurk effect than visually normal controls (15.2% ± 2.3%) across all age groups (P = 0.0024). Effect susceptibility increased with age (P = 0.0003) for amblyopic participants and controls. Both groups showed a similar response pattern to different speakers and syllables, but amblyopic participants invariably demonstrated a less consistent effect. Amblyopia is associated with reduced McGurk effect susceptibility in children and adults. Our findings indicate that the differences do not simply indicate delayed development in children with amblyopia; rather, they represent permanent alterations that persist into adulthood. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.

  14. The relationship between level of autistic traits and local bias in the context of the McGurk effect.

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    Yuta eUjiie

    2015-06-01

    Full Text Available The McGurk effect is a well-known illustration that demonstrates the influence of visual information on hearing in the context of speech perception. Some studies have reported that individuals with autism spectrum disorder (ASD display abnormal processing of audio-visual speech integration, while other studies showed contradictory results. Based on the dimensional model of ASD, we administered two analog studies to examine the link between level of autistic traits, as assessed by the Autism Spectrum Quotient (AQ, and the McGurk effect among a sample of university students. In the first experiment, we found that autistic traits correlated negatively with fused (McGurk responses. Then, we manipulated presentation types of visual stimuli to examine whether the local bias toward visual speech cues modulated individual differences in the McGurk effect. The presentation included four types of visual images, comprising no image, mouth only, mouth and eyes, and full face. The results revealed that global facial information facilitates the influence of visual speech cues on McGurk stimuli. Moreover, individual differences between groups with low and high levels of autistic traits appeared when the full-face visual speech cue with an incongruent voice condition was presented. These results suggest that individual differences in the McGurk effect might be due to a weak ability to process global facial information in individuals with high levels of autistic traits.

  15. bastien Farré, Colis de guerre. Secours alimentaire et organisations humanitaires (1914-1947

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    Yves DENÉCHÈRE

    2014-12-01

    Full Text Available By suggesting a study on the mutual aid actions by means of the war parcel – one of the most symbolic issues of the support actions throughout this period – Sébastien Farré, a scientist in charge of the History House of Geneva University (Maison de l’histoire de l’Université de Genève1 , has a new way of seeing the history of humanitarian organisations. By opening the parcel, by wondering about its route from manufacture to distribution to the beneficiaries, he is rebuilding a humanitarian story crossing the social and cultural history of philanthropic acts. Placing himself into the real world, he departs from the literature written by the humanitarian actors; he is placing again the history of the humanitarian institutions in the field of social policies; he is drawing up a study on the humanitarian economy. In this respect the sources are numerous, issued by ICRC, IUWC, CARE, UNRRA, etc. It’s about looking into the archives by taking advantage of this sojourn as a researcher invited at Columbia University or at Oxford University. The photographical notebook consisting of 32 pages includes 59 quality photos which are not just pictures but constitute a real iconographic corpus. However, it’s a pity that certain photos are not dated and the chronology is manhandled throughout the story.

  16. The McGurk effect in children with autism and Asperger syndrome.

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    Bebko, James M; Schroeder, Jessica H; Weiss, Jonathan A

    2014-02-01

    Children with autism may have difficulties in audiovisual speech perception, which has been linked to speech perception and language development. However, little has been done to examine children with Asperger syndrome as a group on tasks assessing audiovisual speech perception, despite this group's often greater language skills. Samples of children with autism, Asperger syndrome, and Down syndrome, as well as a typically developing sample, were presented with an auditory-only condition, a speech-reading condition, and an audiovisual condition designed to elicit the McGurk effect. Children with autism demonstrated unimodal performance at the same level as the other groups, yet showed a lower rate of the McGurk effect compared with the Asperger, Down and typical samples. These results suggest that children with autism may have unique intermodal speech perception difficulties linked to their representations of speech sounds. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.

  17. Eluding the illusion? Schizophrenia, dopamine and the McGurk effect

    OpenAIRE

    White, Thomas P.; Wigton, Rebekah L.; Joyce, Daniel W.; Tracy eBobin; Christian eFerragamo; Nisha eWasim; Stephen eLisk; Sukhi eShergill

    2014-01-01

    Perceptions are inherently probabilistic; and can be potentially manipulated to induce illusory experience by the presentation of ambiguous or improbable evidence under selective (spatio-temporal) constraints. Accordingly, perception of the McGurk effect, by which individuals misperceive specific incongruent visual and auditory vocal cues, rests upon effective probabilistic inference. Here, we report findings from a behavioral investigation of illusory perception and related metacognitive eva...

  18. Examining the McGurk illusion using high-field 7 Tesla functional MRI.

    Science.gov (United States)

    Szycik, Gregor R; Stadler, Jörg; Tempelmann, Claus; Münte, Thomas F

    2012-01-01

    In natural communication speech perception is profoundly influenced by observable mouth movements. The additional visual information can greatly facilitate intelligibility but incongruent visual information may also lead to novel percepts that neither match the auditory nor the visual information as evidenced by the McGurk effect. Recent models of audiovisual (AV) speech perception accentuate the role of speech motor areas and the integrative brain sites in the vicinity of the superior temporal sulcus (STS) for speech perception. In this event-related 7 Tesla fMRI study we used three naturally spoken syllable pairs with matching AV information and one syllable pair designed to elicit the McGurk illusion. The data analysis focused on brain sites involved in processing and fusing of AV speech and engaged in the analysis of auditory and visual differences within AV presented speech. Successful fusion of AV speech is related to activity within the STS of both hemispheres. Our data supports and extends the audio-visual-motor model of speech perception by dissociating areas involved in perceptual fusion from areas more generally related to the processing of AV incongruence.

  19. Examining the McGurk Illusion Using High-field 7 Tesla Functional MRI

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    Thomas F Münte

    2012-04-01

    Full Text Available In natural communication speech perception is profoundly influenced by observable mouth movements. The additional visual information can greatly facilitate intelligibility but incongruent visual information may also lead to novel percepts that neither match the auditory nor the visual information as evidenced by the McGurk effect. Recent models of AV speech perception accentuate the role of both speech motor areas and the integrative brain sites in the vicinity of the superior temporal sulcus (STS for speech perception. In this event related 7 Tesla fMRI study we used three naturally spoken syllable pairs with matching AV information and one syllable pair designed to elicit the McGurk illusion. The data analysis focused on brain sites involved in processing and fusing of AV speech and engaged in the analysis of auditory and visual differences within AV presented speech. Successful fusion of AV speech is related to activity within the STS of both hemispheres. . Our data supports and extends the audio-visual-motor model of speech perception by dissociating areas involved in perceptual fusion from areas more generally related to the processing of AV incongruence.

  20. Tuning and disrupting the brain – modulating the McGurk illusion with electrical stimulation

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    Lucas M Marques

    2014-08-01

    Full Text Available In the so-called McGurk illusion, when the synchronized presentation of the visual stimulus /ga/ is paired with the auditory stimulus /ba/, people in general hear it as /da/. Multisensory integration processing underlying this illusion seems to occur within the Superior Temporal Sulcus (STS. Herein, we present evidence demonstrating that bilateral cathodal transcranial direct current stimulation (tDCS of this area can decrease the McGurk illusion-type responses. Additionally, we show that the manipulation of this audio-visual integrated output occurs irrespective of the number of eye-fixations on the mouth of the speaker. Bilateral anodal tDCS of the Parietal Cortex also modulates the illusion, but in the opposite manner, inducing more illusion-type responses. This is the first demonstration of using non-invasive brain stimulation to modulate multisensory speech perception in an illusory context (i.e., both increasing and decreasing illusion-type responses to a verbal audio-visual integration task. These findings provide clear evidence that both the superior temporal and parietal areas contribute to multisensory integration processing related to speech perception. Specifically, STS seems fundamental for the temporal synchronization and integration of auditory and visual inputs. For its part, PPC may adjust the arrival of incoming audio and visual information to STS thereby enhancing their interaction in this latter area.

  1. Auditory-visual speech integration by prelinguistic infants: perception of an emergent consonant in the McGurk effect.

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    Burnham, Denis; Dodd, Barbara

    2004-12-01

    The McGurk effect, in which auditory [ba] dubbed onto [ga] lip movements is perceived as "da" or "tha," was employed in a real-time task to investigate auditory-visual speech perception in prelingual infants. Experiments 1A and 1B established the validity of real-time dubbing for producing the effect. In Experiment 2, 4 1/2-month-olds were tested in a habituation-test paradigm, in which an auditory-visual stimulus was presented contingent upon visual fixation of a live face. The experimental group was habituated to a McGurk stimulus (auditory [ba] visual [ga]), and the control group to matching auditory-visual [ba]. Each group was then presented with three auditory-only test trials, [ba], [da], and [(delta)a] (as in then). Visual-fixation durations in test trials showed that the experimental group treated the emergent percept in the McGurk effect, [da] or [(delta)a], as familiar (even though they had not heard these sounds previously) and [ba] as novel. For control group infants [da] and [(delta)a] were no more familiar than [ba]. These results are consistent with infants' perception of the McGurk effect, and support the conclusion that prelinguistic infants integrate auditory and visual speech information.

  2. How is the McGurk effect modulated by Cued Speech in deaf and hearing adults ?

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    Clémence eBayard

    2014-05-01

    Full Text Available Speech perception for both hearing and deaf people involves an integrative process between auditory and lip-reading information. In order to disambiguate information from lips, manual cues from Cued Speech may be added. Cued Speech (CS is a system of manual aids developed to help deaf people to clearly and completely understand speech visually (Cornett, 1967. Within this system, both labial and manual information, as lone input sources, remain ambiguous. Perceivers, therefore, have to combine both types of information in order to get one coherent percept. In this study, we examined how audio-visual (AV integration is affected by the presence of manual cues and on which form of information (auditory, labial or manual the CS receptors primarily rely. To address this issue, we designed a unique experiment that implemented the use of AV McGurk stimuli (audio /pa/ and lip-reading /ka/ which were produced with or without manual cues. The manual cue was congruent with either auditory information, lip information or the expected fusion. Participants were asked to repeat the perceived syllable aloud. Their responses were then classified into four categories: audio (when the response was /pa/, lip-reading (when the response was /ka/, fusion (when the response was /ta/ and other (when the response was something other than /pa/, /ka/ or /ta/. Data were collected from hearing impaired individuals who were experts in CS (all of which had either cochlear implants or binaural hearing aids; N=8, hearing-individuals who were experts in CS (N = 14 and hearing-individuals who were completely naïve of CS (N = 15. Results confirmed that, like hearing-people, deaf people can merge auditory and lip-reading information into a single unified percept. Without manual cues, McGurk stimuli induced the same percentage of fusion responses in both groups. Results also suggest that manual cues can modify the AV integration and that their impact differs between hearing and deaf

  3. How is the McGurk effect modulated by Cued Speech in deaf and hearing adults?

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    Bayard, Clémence; Colin, Cécile; Leybaert, Jacqueline

    2014-01-01

    Speech perception for both hearing and deaf people involves an integrative process between auditory and lip-reading information. In order to disambiguate information from lips, manual cues from Cued Speech may be added. Cued Speech (CS) is a system of manual aids developed to help deaf people to clearly and completely understand speech visually (Cornett, 1967). Within this system, both labial and manual information, as lone input sources, remain ambiguous. Perceivers, therefore, have to combine both types of information in order to get one coherent percept. In this study, we examined how audio-visual (AV) integration is affected by the presence of manual cues and on which form of information (auditory, labial or manual) the CS receptors primarily rely. To address this issue, we designed a unique experiment that implemented the use of AV McGurk stimuli (audio /pa/ and lip-reading /ka/) which were produced with or without manual cues. The manual cue was congruent with either auditory information, lip information or the expected fusion. Participants were asked to repeat the perceived syllable aloud. Their responses were then classified into four categories: audio (when the response was /pa/), lip-reading (when the response was /ka/), fusion (when the response was /ta/) and other (when the response was something other than /pa/, /ka/ or /ta/). Data were collected from hearing impaired individuals who were experts in CS (all of which had either cochlear implants or binaural hearing aids; N = 8), hearing-individuals who were experts in CS (N = 14) and hearing-individuals who were completely naïve of CS (N = 15). Results confirmed that, like hearing-people, deaf people can merge auditory and lip-reading information into a single unified percept. Without manual cues, McGurk stimuli induced the same percentage of fusion responses in both groups. Results also suggest that manual cues can modify the AV integration and that their impact differs between hearing and deaf people.

  4. Cross-modal discrepancies in coarticulation and the integration of speech information: the McGurk effect with mismatched vowels.

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    Green, K P; Gerdeman, A

    1995-12-01

    Two experiments examined the impact of a discrepancy in vowel quality between the auditory and visual modalities on the perception of a syllable-initial consonant. One experiment examined the effect of such a discrepancy on the McGurk effect by cross-dubbing auditory /bi/ tokens onto visual /ga/ articulations (and vice versa). A discrepancy in vowel category significantly reduced the magnitude of the McGurk effect and changed the pattern of responses. A 2nd experiment investigated the effect of such a discrepancy on the speeded classification of the initial consonant. Mean reaction times to classify the tokens increased when the vowel information was discrepant between the 2 modalities but not when the vowel information was consistent. These experiments indicate that the perceptual system is sensitive to cross-modal discrepancies in the coarticulatory information between a consonant and its following vowel during phonetic perception.

  5. Individual Differences on the McGurk Effect: An Examination with the Autism Trait and Schizotypal Personality

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    Yuta Ujiie

    2011-10-01

    Full Text Available The McGurk effect is a perceptual phenomenon that demonstrates interaction between hearing and vision in speech perception. This effect may be experienced when a visual of the production of a phoneme is dubbed with a sound recording of a different phoneme being spoken wherein the perceived phoneme is often the third intermediate phoneme. In the present study we examined the potential individual differences in the McGurk effect among 51 healthy students. The results suggested that people with higher scores for schizophrenic or autistic traits, respectively, might report less /ka/ responses (visually captured responses but more /ta/ responses (vision-audio mixed responses in the McGurk condition (visually /pa/ but auditor/ka/. This indicates that such people might show a preference for auditory information over visual information. Both schizophrenia and autism might have deficits in social functioning. If an individual has a poor level of interpersonal skills this would reflect in the result since he/she might not be able to read others' lips automatically.

  6. Eluding the illusion? Schizophrenia, dopamine and the McGurk effect

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    White, Thomas P.; Wigton, Rebekah L.; Joyce, Dan W.; Bobin, Tracy; Ferragamo, Christian; Wasim, Nisha; Lisk, Stephen; Shergill, Sukhwinder S.

    2014-01-01

    Perceptions are inherently probabilistic; and can be potentially manipulated to induce illusory experience by the presentation of ambiguous or improbable evidence under selective (spatio-temporal) constraints. Accordingly, perception of the McGurk effect, by which individuals misperceive specific incongruent visual and auditory vocal cues, rests upon effective probabilistic inference. Here, we report findings from a behavioral investigation of illusory perception and related metacognitive evaluation during audiovisual integration, conducted in individuals with schizophrenia (n = 30) and control subjects (n = 24) matched in terms of age, sex, handedness and parental occupation. Controls additionally performed the task after an oral dose of amisulpride (400 mg). Individuals with schizophrenia were observed to exhibit illusory perception less frequently than controls, despite non-significant differences in perceptual performance during control conditions. Furthermore, older individuals with schizophrenia exhibited reduced rates of illusory perception. Subsequent analysis revealed a robust inverse relationship between illness chronicity and the illusory perception rate in this group. Controls demonstrated non-significant modulation of perception by amisulpride; amisulpride was, however, found to elicit increases in subjective confidence in perceptual performance. Overall, these findings are consistent with the idea that impairments in probabilistic inference are exhibited in schizophrenia and exacerbated by illness chronicity. The latter suggests that associated processes are a potentially worthwhile target for therapeutic intervention. PMID:25140138

  7. Eluding the illusion? Schizophrenia, dopamine and the McGurk effect

    Directory of Open Access Journals (Sweden)

    Thomas P White

    2014-08-01

    Full Text Available Perceptions are inherently probabilistic; and can be potentially manipulated to induce illusory experience by the presentation of ambiguous or improbable evidence under selective (spatio-temporal constraints. Accordingly, perception of the McGurk effect, by which individuals misperceive specific incongruent auditory and visual vocal cues, rests upon effective probabilistic inference. Here, we report findings from a behavioural investigation of illusory perception and related metacognitive evaluation during audiovisual integration, conducted in individuals with schizophrenia (n=30 and control subjects (n=24 matched in terms of age, sex, handedness and parental occupation. Controls additionally performed the task after an oral dose of amisulpride (400 mg. Individuals with schizophrenia were observed to exhibit illusory perception less frequently than controls, despite non-significant differences in perceptual performance during control conditions. Furthermore, older individuals with schizophrenia exhibited reduced rates of illusory perception. Subsequent analysis revealed a robust inverse relationship between illness chronicity and the illusory perception rate in this group. Controls demonstrated non-significant modulation of perception by amisulpride; amisulpride was, however, found to elicit increases in subjective confidence in perceptual performance. Overall, these findings are consistent with the idea that impairments in probabilistic inference are exhibited in schizophrenia and exacerbated by illness chronicity. The latter suggests that associated processes are a potentially worthwhile target for therapeutic intervention.

  8. The McGurk effect: An investigation of attentional capacity employing response times.

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    Altieri, Nicholas; Lentz, Jennifer J; Townsend, James T; Wenger, Michael J

    2016-08-01

    This paper proposes a novel approach to assess audiovisual integration for both congruent and incongruent speech stimuli using reaction times (RT). The experiments are based on the McGurk effect, in which a listener is presented with incongruent audiovisual speech signals. A typical example involves the auditory consonant/b/combined with a visually articulated/g/, often yielding a perception of/d/. We quantify the amount of integration relative to the predictions of a parallel independent model as a function of attention and congruency between auditory and visual signals. We assessed RT distributions for congruent and incongruent auditory and visual signals in a within-subjects signal detection paradigm under conditions of divided versus focused attention. Results showed that listeners often received only minimal benefit from congruent auditory visual stimuli, even when such information could have improved performance. Incongruent stimuli adversely affected performance in divided and focused attention conditions. Our findings support a parallel model of auditory-visual integration with interactions between auditory and visual channels.

  9. Music in Spain in the 1670s through the eyes of Sébastien Chièze and Constantijn Huygens

    Directory of Open Access Journals (Sweden)

    Rasch, Rudolf A.

    2007-12-01

    Full Text Available In this contribution the various remarks about music in Spain that can be found in the correspondence between Sébastien Chièze (envoy on behalf of the Prince of Orange in Madrid and Constantijn Huygens (The Hague from 1672 to 1679 are discussed. Huygens asked Chièze to find for him a copy of Salinas’s De musica (1577, as well as Spanish airs and pieces for guitar. It took Chièze two years to find a copy of De musica in Spain and have it sent safely to Holland. Huygens did not like the Spanish airs sent by Chièze, by composers such as Juan del Vado, José Marín, Cristóbal Galán, and Juan Hidalgo. He found them too “African”. Nor did he like the guitar tablature, which turned the notation as he was used to seeing it upside down. Chièze also had a guitar made for Huygens in Madrid, but this instrument also met with disapproval. In the end, Chièze asked two Bolognese acquaintances, Giulio and Guido Bovio, to search for a suitable lute for Huygens in Bologna. They found two, but it is unknown whether these ever arrived in Holland. The contribution shows the importance of foreign (diplomatic contacts in the acquisition of musical articles, such as books about music, musical compositions and musical instruments.

    Este artículo trata de las diversas observaciones a propósito de la música en España, que se encuentran en la correspondencia entre Sébastien Chièze (embajador del Príncipe de Orange en Madrid y Constantijn Huygens (La Haya, entre 1672 y 1679. Huygens pidió a Chièze que le encontrara un ejemplar del De musica de Salinas (1577, así como tonadas españolas y piezas para guitarra. A Chièze le llevó dos años hallar una copia del De musica en territorio español y hacer que el libro llegara a Holanda sano y salvo. Las tonadas remitidas por Chièze (de compositores tales como Juan del Vado, José Marín, Cristóbal Galán y Juan Hidalgo, no gustaron nada a Huygens, que las halló demasiado “africanas”. Como

  10. Atypical audio-visual speech perception and McGurk effects in children with specific language impairment.

    Science.gov (United States)

    Leybaert, Jacqueline; Macchi, Lucie; Huyse, Aurélie; Champoux, François; Bayard, Clémence; Colin, Cécile; Berthommier, Frédéric

    2014-01-01

    Audiovisual speech perception of children with specific language impairment (SLI) and children with typical language development (TLD) was compared in two experiments using /aCa/ syllables presented in the context of a masking release paradigm. Children had to repeat syllables presented in auditory alone, visual alone (speechreading), audiovisual congruent and incongruent (McGurk) conditions. Stimuli were masked by either stationary (ST) or amplitude modulated (AM) noise. Although children with SLI were less accurate in auditory and audiovisual speech perception, they showed similar auditory masking release effect than children with TLD. Children with SLI also had less correct responses in speechreading than children with TLD, indicating impairment in phonemic processing of visual speech information. In response to McGurk stimuli, children with TLD showed more fusions in AM noise than in ST noise, a consequence of the auditory masking release effect and of the influence of visual information. Children with SLI did not show this effect systematically, suggesting they were less influenced by visual speech. However, when the visual cues were easily identified, the profile of responses to McGurk stimuli was similar in both groups, suggesting that children with SLI do not suffer from an impairment of audiovisual integration. An analysis of percent of information transmitted revealed a deficit in the children with SLI, particularly for the place of articulation feature. Taken together, the data support the hypothesis of an intact peripheral processing of auditory speech information, coupled with a supra modal deficit of phonemic categorization in children with SLI. Clinical implications are discussed.

  11. Seeing voices: High-density electrical mapping and source-analysis of the multisensory mismatch negativity evoked during the McGurk illusion.

    Science.gov (United States)

    Saint-Amour, Dave; De Sanctis, Pierfilippo; Molholm, Sophie; Ritter, Walter; Foxe, John J

    2007-02-01

    Seeing a speaker's facial articulatory gestures powerfully affects speech perception, helping us overcome noisy acoustical environments. One particularly dramatic illustration of visual influences on speech perception is the "McGurk illusion", where dubbing an auditory phoneme onto video of an incongruent articulatory movement can often lead to illusory auditory percepts. This illusion is so strong that even in the absence of any real change in auditory stimulation, it activates the automatic auditory change-detection system, as indexed by the mismatch negativity (MMN) component of the auditory event-related potential (ERP). We investigated the putative left hemispheric dominance of McGurk-MMN using high-density ERPs in an oddball paradigm. Topographic mapping of the initial McGurk-MMN response showed a highly lateralized left hemisphere distribution, beginning at 175 ms. Subsequently, scalp activity was also observed over bilateral fronto-central scalp with a maximal amplitude at approximately 290 ms, suggesting later recruitment of right temporal cortices. Strong left hemisphere dominance was again observed during the last phase of the McGurk-MMN waveform (350-400 ms). Source analysis indicated bilateral sources in the temporal lobe just posterior to primary auditory cortex. While a single source in the right superior temporal gyrus (STG) accounted for the right hemisphere activity, two separate sources were required, one in the left transverse gyrus and the other in STG, to account for left hemisphere activity. These findings support the notion that visually driven multisensory illusory phonetic percepts produce an auditory-MMN cortical response and that left hemisphere temporal cortex plays a crucial role in this process.

  12. Disentangling unisensory from fusion effects in the attentional modulation of McGurk effects: a Bayesian modeling study suggests that fusion is attention-dependent

    DEFF Research Database (Denmark)

    Schwartz, Jean-Luc; Tiiippana, Kaisa; Andersen, Tobias

    2010-01-01

    The McGurk effect has been shown to be modulated by attention. However, it remains unclear whether attentional effects are due to changes in unisensory processing or in the fusion mechanism. In this paper, we used published experimental data showing that distraction of visual attention weakens th...... Selection criterion. Our findings suggest that distraction of visual attention affects fusion by decreasing the weight of the visual input.......The McGurk effect has been shown to be modulated by attention. However, it remains unclear whether attentional effects are due to changes in unisensory processing or in the fusion mechanism. In this paper, we used published experimental data showing that distraction of visual attention weakens...... the McGurk effect, to fit either the Fuzzy Logical Model of Perception (FLMP) in which the fusion mechanism is fixed, or a variant of it in which the fusion mechanism could be varied depending on attention. The latter model was associated with a larger likelihood when assessed with a Bayesian Model...

  13. Antioxidant Properties of Diospyros Preussi (Ebenaceae Gurke ...

    African Journals Online (AJOL)

    Erah

    2007-02-24

    Feb 24, 2007 ... Several of these plants produce fruits which have been ... neutralised by a battery of antioxidants. Thus, oxidative stress is .... of 20 % lithium sulphate and 0.2 ml of 20 % ... presence of certain transition metal ions (e.g. iron and ...

  14. Analysis of genetic structure in Melia volkensii (Gurke.) populations ...

    African Journals Online (AJOL)

    Administrator

    between populations in the eastern and the coastal regions with 21.1%, (P < 0.0002) of the total variation attributed to differences ... especially in the highly settled areas. ... to rapidly estimate the patterns and distribution of genetic variation for ... Altitude (m) Region .... application to human mitochondrial DNA restriction data.

  15. bastien Broca, Utopie du logiciel libre. Du bricolage informatique à la réinvention sociale

    OpenAIRE

    Goëta, Samuel

    2014-01-01

    Traitant des pratiques et des conceptions du logiciel libre mais aussi, plus largement, du mouvement pour l’ouverture des savoirs, Utopie du logiciel libre ambitionne, premièrement, de nourrir une réflexion critique sur l’ethos du libre au sens d’un « ensemble de valeurs qui constituent un cadre pour l’action et s’actualisent dans des pratiques » (p. 24) et, deuxièmement, d’élaborer une sociologie critique du libre. Reprenant la notion d’utopie concrète chez Ernst Bloch (Le principe Espérance...

  16. Louis Sébastien Tredern de Lézérec (1780-18?), a forgotten pioneer of chick embryology.

    Science.gov (United States)

    Beetschen, J C

    1995-04-01

    Tredern's thesis on chick embryo development was submitted in Jena (Germany) in 1808 and seems to have been completely overlooked by historians of embryology during the 20th century. However, K.E. von Baer and C. Pander were much interested in that thesis in 1816-1817, when they resumed work on the chick embryo. Tredern, who was born in France in 1780, had then left Germany and abandoned his studies, but von Baer tried to find trace of him throughout his life, wanting to pay homage to his pioneer work. Von Baer published a short biographical notice (1874), which was later extended by Stieda (1901). The accuracy of Tredern's observations and the reasons that could have justified von Baer's interest are discussed. Tredern went back to Paris in 1811 to submit a second medical thesis, the value of which is also considered. It is also shown that, in the teaching of embryology, 18th century preformation concepts were still vivid, remaining in French textbooks of the period 1800-1830. This situation strongly contrasts with the new epigenetic views that were developed by the German scientists with whom Tredern had performed his studies.

  17. Hearing Mouth Shapes: Sound Symbolism and the Reverse McGurk Effect

    Directory of Open Access Journals (Sweden)

    Charles Spence

    2012-09-01

    Full Text Available In their recent article, Sweeny, Guzman-Martinez, Ortega, Grabowecky, and Suzuki (2012 demonstrate that heard speech sounds modulate the perceived shape of briefly presented visual stimuli. Ovals, whose aspect ratio (relating width to height varied on a trial-by-trial basis, were rated as looking wider when a /woo/ sound was presented, and as taller when a /wee/ sound was presented instead. On the one hand, these findings add to a growing body of evidence demonstrating that audiovisual correspondences can have perceptual (as well as decisional effects. On the other hand, they prompt a question concerning their origin. Although the currently popular view is that crossmodal correspondences are based on the internalization of the natural multisensory statistics of the environment (see Spence, 2011, these new results suggest instead that certain correspondences may actually be based on the sensorimotor responses associated with human vocalizations. As such, the findings of Sweeny et al. help to breathe new life into Sapir's (1929 once-popular “embodied” explanation of sound symbolism. Furthermore, they pose a challenge for those psychologists wanting to determine which among a number of plausible accounts best explains the available data on crossmodal correspondences.

  18. Hearing mouth shapes: Sound symbolism and the reverse McGurk effect.

    Science.gov (United States)

    Spence, Charles; Deroy, Ophelia

    2012-01-01

    In their recent article, Sweeny, Guzman-Martinez, Ortega, Grabowecky, and Suzuki (2012) demonstrate that heard speech sounds modulate the perceived shape of briefly presented visual stimuli. Ovals, whose aspect ratio (relating width to height) varied on a trial-by-trial basis, were rated as looking wider when a /woo/ sound was presented, and as taller when a /wee/ sound was presented instead. On the one hand, these findings add to a growing body of evidence demonstrating that audiovisual correspondences can have perceptual (as well as decisional) effects. On the other hand, they prompt a question concerning their origin. Although the currently popular view is that crossmodal correspondences are based on the internalization of the natural multisensory statistics of the environment (see Spence, 2011), these new results suggest instead that certain correspondences may actually be based on the sensorimotor responses associated with human vocalizations. As such, the findings of Sweeny et al. help to breathe new life into Sapir's (1929) once-popular "embodied" explanation of sound symbolism. Furthermore, they pose a challenge for those psychologists wanting to determine which among a number of plausible accounts best explains the available data on crossmodal correspondences.

  19. Lecture de Sébastien Farré, La Suisse et l’Espagne de Franco. De la guerre civile à la mort du dictateur (1936-1975

    Directory of Open Access Journals (Sweden)

    Rose Duroux

    2010-01-01

    Full Text Available Se estudian las relaciones entre las autoridades suizas y el gobierno del general Franco en sus diferentes aspectos (económico, social, cultural, político. Abarca del 18 de julio de 1936, inicio de la guerra civil, al 27 de noviembre de 1975, día de la entronización del rey Juan Carlos. Las relaciones económicas entre los dos países ocupan un lugar importante lo cual era primordial al tratarse de un país como Suiza cuyo protagonismo está determinado por la potencia económica y financiera de sus empresas en la economía mundial. Conociendo además la dimensión ideológica de la guerra civil y la evolución del debate público en la sociedad suiza con respecto al régimen franquista, importaba aprehender la representación del otro: cómo es percibido el español/el suizo respectivamente en ambos países; cuál es la evolución de la opinión con respecto al general Franco. Se aborda la cuestión del exilio a raíz de la guerra civil así como la emigración que se inicia a principios de los 60.This book presents the relations betwen the Swiss authorities and the government of general Franco in their different aspects (economic, social, cultural, political. The study covers from July 18th, 1936, beginning of the civil war, to November 27 th, 1975, day of the enthronement of king Juan Carlos. An important place is reserved for economic relations between both countries, which was obvious for a country such as Switzerland whose international role is notably determined by the economic and financial potency of its firms in worldwide economy. Knowing the ideological dimension of the civil war as well as the existence of a public debate in the Swiss society about the Spanish regime, it was essential to grasp the representation of the Other: how the Spanish and the Swiss are perceived respectively; what is the Swiss position but also the evolution of public opinion regarding general Franco. The question of exile during the civil war and world war II is also tackled, as the important migratory movement in the sixties.

  20. Bonnet-Carbonel Jocelyne, Fournier Laurent-Sébastien, Dir., Peurs et risque au cœur de la fête

    Directory of Open Access Journals (Sweden)

    Claude Rivière

    2011-03-01

    Full Text Available Depuis quelque vingt ans que fonctionne le réseau de coopération ethnologique et historiographique sous le couvert du Conseil de l’Europe, il n’a cessé de tenir son ate­lier annuel – par exemple en Bulgarie : Malmorts, revenants et vampires en Europe (L’Harmattan, 2006 ou à Nîmes – pour ces risques et ces peurs de l’Occident mo­derne, soit à table, soit dans les rituels festifs juvéniles. L’éditeur a choisi pour cou­verture des vampires à la couleur de sang caillé. Autour de la table, des je...

  1. Developmental Trajectory of Audiovisual Speech Integration in Early Infancy. A Review of Studies Using the McGurk Paradigm

    Directory of Open Access Journals (Sweden)

    Tomalski Przemysław

    2015-10-01

    Full Text Available Apart from their remarkable phonological skills young infants prior to their first birthday show ability to match the mouth articulation they see with the speech sounds they hear. They are able to detect the audiovisual conflict of speech and to selectively attend to articulating mouth depending on audiovisual congruency. Early audiovisual speech processing is an important aspect of language development, related not only to phonological knowledge, but also to language production during subsequent years. Th is article reviews recent experimental work delineating the complex developmental trajectory of audiovisual mismatch detection. Th e central issue is the role of age-related changes in visual scanning of audiovisual speech and the corresponding changes in neural signatures of audiovisual speech processing in the second half of the first year of life. Th is phenomenon is discussed in the context of recent theories of perceptual development and existing data on the neural organisation of the infant ‘social brain’.

  2. INCIDENCE AND CONTROL OF SEED - BORNE FUNGAL INFECTIONS ASSOCIATED WITH POST - GERMINATION MORTALITY IN SEEDLINGS OF Melia volkensii GURKE

    Directory of Open Access Journals (Sweden)

    Mulanda ES

    2013-09-01

    Full Text Available A laboratory study was carried out at the School of Biological Sciences, Chiromo Campus, University of Nairobi, for identification of seed- borne fungi that emerge during germination of M. volkensii seeds. The study sought to determine the incidence, pathological symptoms and effects of the fungi on post -germination survival of seedlings. Mature seeds collected from wild trees in three agro-climatic zones in semi arid eastern Kenya were scarified by nipping and slitting of the testa and divided into two groups. The treatment group received a single pulse pre-treatment consisting of a 30 minute soak in 1% (m/v Bavistin, while the control group was soaked in tap water. Aspergillus flavus and Rhizopus stolonifer infections emerged in the control group. A Mann - Whitney U test showed the control group as having significantly higher infections with both fungi (range of p values = 0.003 to 0.010 during and after germination than the fungicide-treated group. Post-germination seedling survival was also significantly enhanced by 31.66% in the treated group relative to the control (range of p values = 0.004 to 0.010. A single pre- treatment with the systemic fungicide Bavistin may be recommended for reduction of seedling mortality in M. volkensii during and after germination.

  3. Open your eyes and listen carefully. Auditory and audiovisual speech perception and the McGurk effect in aphasia

    NARCIS (Netherlands)

    Klitsch, Julia Ulrike

    2008-01-01

    This dissertation investigates speech perception in three different groups of native adult speakers of Dutch; an aphasic and two age-varying control groups. By means of two different experiments it is examined if the availability of visual articulatory information is beneficial to the auditory speec

  4. Open your eyes and listen carefully. Auditory and audiovisual speech perception and the McGurk effect in aphasia

    NARCIS (Netherlands)

    Klitsch, Julia Ulrike

    2008-01-01

    This dissertation investigates speech perception in three different groups of native adult speakers of Dutch; an aphasic and two age-varying control groups. By means of two different experiments it is examined if the availability of visual articulatory information is beneficial to the auditory speec

  5. Interaction of various flow systems in small alpine catchments: conceptual model of the upper Gurk Valley aquifer, Carinthia, Austria

    Science.gov (United States)

    Hilberg, Sylke; Riepler, Franz

    2016-08-01

    Small alpine valleys usually show a heterogeneous hydraulic situation. Recurring landslides create temporal barriers for the surface runoff. As a result of these postglacial processes, temporal lakes form, and thus lacustrine fine-grained sedimentation intercalates with alluvial coarse-grained layers. A sequence of alluvial sediments (confined and thus well protected aquifers) and lacustrine sediments (aquitards) is characteristic for such an environment. The hydrogeological situation of fractured hard-rock aquifers in the framing mountain ranges is characterized by superficially high hydraulic conductivities as the result of tectonic processes, deglaciation and postglacial weathering. Fracture permeability and high hydraulic gradients in small-scaled alpine catchments result in the interaction of various flow systems in various kinds of aquifers. Spatial restrictions and conflicts between the current land use and the requirements of drinking-water protection represent a special challenge for water resource management in usually densely populated small alpine valleys. The presented case study describes hydrogeological investigations within the small alpine valley of the upper Gurktal (Upper Carinthia, Austria) and the adjacent Höllenberg Massif (1,772 m above sea level). Hydrogeological mapping, drilling, and hydrochemical and stable isotope analyses of springs and groundwater were conducted to identify a sustainable drinking-water supply for approximately 1,500 inhabitants. The results contribute to a conceptual hydrogeological model with three interacting flow systems. The local and the intermediate flow systems are assigned to the catchment of the Höllenberg Massif, whereas the regional flow system refers to the bordering Gurktal Alps to the north and provides an appropriate drinking water reservoir.

  6. New insights into life and death of the self-styled estonian embryologist, Louis Sébastien Marie de Tredern de Lézerec (1780-1818) / Jean-Claude Beetschen, Pierre Baudrier

    Index Scriptorium Estoniae

    Beetschen, Jean-Claude

    2010-01-01

    L. S. M. de Tredern de Lézerec´i teadustööst embrüoloogina (kuni 1809). K. E. Von Beari katsetest leida de Trederni kohta teavet, artikli autorite leitud uusi andmeid tema elukäigust aastatel 1802-1818, sh tegevusest Mazarini raamatukogus (1813-1816)

  7. New insights into life and death of the self-styled estonian embryologist, Louis Sébastien Marie de Tredern de Lézerec (1780-1818) / Jean-Claude Beetschen, Pierre Baudrier

    Index Scriptorium Estoniae

    Beetschen, Jean-Claude

    2010-01-01

    L. S. M. de Tredern de Lézerec´i teadustööst embrüoloogina (kuni 1809). K. E. Von Beari katsetest leida de Trederni kohta teavet, artikli autorite leitud uusi andmeid tema elukäigust aastatel 1802-1818, sh tegevusest Mazarini raamatukogus (1813-1816)

  8. Using a Functional Simulation of Crisis Management to Test the C2 Agility Model Parameters on Key Performance Variables

    Science.gov (United States)

    2013-06-01

    Isabelle Turcotte (Université Laval) Sébastien Tremblay (Université Laval) Philip Farrell (DRDC Toronto) Marie-Eve Jobidon (DRDC Toronto...Using a Functional Simulation of Crisis Management to test the C2 Agility Model Isabelle Turcotte – Université Laval Sébastien Tremblay – Université

  9. Audiovisual Integration of Speech in a Patient with Broca’s Aphasia

    DEFF Research Database (Denmark)

    Andersen, Tobias; Starrfelt, Randi

    2015-01-01

    's area is necessary for audiovisual integration of speech. Here we describe a patient with Broca's aphasia who experienced the McGurk illusion. This indicates that an intact Broca's area is not necessary for audiovisual integration of speech. The McGurk illusions this patient experienced were atypical......, which could be due to Broca's area having a more subtle role in audiovisual integration of speech. The McGurk illusions of a control subject with Wernicke's aphasia were, however, also atypical. This indicates that the atypical McGurk illusions were due to deficits in speech processing...

  10. Multimodal integration in statistical learning

    DEFF Research Database (Denmark)

    Mitchell, Aaron; Christiansen, Morten Hyllekvist; Weiss, Dan

    2014-01-01

    incongruent, which we predicted would produce the McGurk illusion, resulting in the perception of an audiovisual syllable (e.g., /ni/). In this way, we used the McGurk illusion to manipulate the underlying statistical structure of the speech streams, such that perception of these illusory syllables...

  11. Reference: 48 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available opsis. 1 75-86 12943542 2003 Jan The Plant journal Baud S辿bastien|Caboche Michel|Guyon Virginie|Kronenberger Jocelyne|Lepiniec Lo誰c|Miquel Martine|Rochat Christine|Wuill竪me Sylvie

  12. Synthetic Infrared Scene: Improving the KARMA IRSG Module and Signature Modelling Tool SMAT

    Science.gov (United States)

    2011-03-01

    Desmeules Alexandre Bastien Louis Tanguay Informatique inc. Geoffroy Rivet-Sabourin Technologie Intelligence Image inc. Prepared By: Louis Tanguay... Informatique inc. 825 Boulevard Lebourgneuf, Bureau 204 Québec, Canada G2J 0B9 Contractor’s Document Number: LTI-SIS-2011-1 Contract Project Manager...Alexandre Bastien Louis Tanguay Informatique inc. Geoffroy Rivet-Sabourin Technologie Intelligence Image inc. Prepared By: Louis Tanguay

  13. Congratulations to the Class of 2015!

    CERN Multimedia

    Anaïs Schaeffer

    2016-01-01

    Five apprentices who left CERN in June having successfully completed their training were awarded their diplomas during the Fête de l’apprentissage in Geneva.   Bastien Gallay (fifth from right) received the 2015 Union Industrielle Genevoise prize during an official ceremony on 8 December in the presence of Pierre Maudet, Geneva state councillor (right). In September, the five CERN apprentices from the 2011-2015 year group were awarded their Certificat fédéral de capacité (CFC) during the Fête de l’apprentissage, which takes place at the Geneva Arena every year. The apprentices, three electronics technicians, Bastien Gallay, Sébastien Hiltbrunner and Valentino Ranieri, and two physics laboratory technicians, Loïc Baravaglio and Yan Reynard, spent four years in CERN’s workshops and laboratories honing their skills and acquiring the necessary experience for their future careers. We are very please...

  14. Adaptability in Crisis Management: The Role of Organizational Structure

    Science.gov (United States)

    2013-06-01

    DRDC Toronto) Alexandre Labrecque (Université Laval) Isabelle Turcotte (Université Laval) Vincent Rousseau (Université de Montréal) Sébastien...Arlington, VA. Marie-Eve Jobidon – DRDC Toronto Alexandre Labrecque – Université Laval Isabelle Turcotte – Université Laval Vincent Rousseau

  15. Reference: 19 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 19 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u12569131i Lopez-Molina Luis... 410-8 12569131 2003 Feb Genes & development Chua Nam-Hai|Kinoshita Natsuko|Lopez-Molina Luis|Mongrand S辿bastien

  16. Krøyer – i internationalt lys

    DEFF Research Database (Denmark)

    Indhold: Jan Gorm Madsen: Ud i verden. Det moderne udstillingsliv i Tyskland, Østrig-Ungarn & Italien. Marianne Saabye: Det akademiske mesterstykke ; Krøyer & Bastien-Lepage ; Forår i Cernay-la-Ville ; "Banden fra Bretagne" ; På salon og verdensudstilling 1877-81 ; Krøyer & Liebermann ; Krøyer & ......: Krøyer & Sorolla...

  17. Flicker as a tool for characterizing planets though asterodensity profiling

    DEFF Research Database (Denmark)

    Kipping, D. M.; Bastien, F. A.; Stassun, K. G.

    2014-01-01

    Variability in the time series brightness of a star on a timescale of 8 hr, known as "flicker," has been previously demonstrated to serve as a proxy for the surface gravity of a star by Bastien et al. Although surface gravity is crucial for stellar classification, it is the mean stellar density...

  18. 2nd February 2011 - EPFL Vice President, Academic Affairs, P. Gillet signing the guest book with Director-General R. Heuer.

    CERN Multimedia

    Jean-Claude Gadmer

    2011-01-01

    On photograph 16: form left to right: Nicolas Guérin, Willy Zwaenepoel, Bastien Confino, Frédérick Bordry (CERN), Philippe Gillet, Benoît Deveaud-Plédran, Dominique Bonvin, Gérard Escher, Jacques Giovanola, Tatsuya Nakada, Stéphane Decoutère, Ambrogio Fasoli, Demetri Psaltis, Olivier Schneider, Aurelio Bay and Leonid Rivkin.

  19. Designing Composite Structures for Low-Velocity Impact

    Science.gov (United States)

    1990-08-01

    discussions having absolutely nothing to do with composites. Thanks to Laurent Bastien and Caroline Voituriez, my academic "Lafayettes," whose good...651 3.9 Time to acquire test data ++ + + = ++ ++ + 617 3.7 Trainino costs for technicians ++ .+ ++ + + + 553 3.4 Energy rance .+ + + + + + 545

  20. What you see isn't always what you get: Auditory word signals trump consciously perceived words in lexical access.

    Science.gov (United States)

    Ostrand, Rachel; Blumstein, Sheila E; Ferreira, Victor S; Morgan, James L

    2016-06-01

    Human speech perception often includes both an auditory and visual component. A conflict in these signals can result in the McGurk illusion, in which the listener perceives a fusion of the two streams, implying that information from both has been integrated. We report two experiments investigating whether auditory-visual integration of speech occurs before or after lexical access, and whether the visual signal influences lexical access at all. Subjects were presented with McGurk or Congruent primes and performed a lexical decision task on related or unrelated targets. Although subjects perceived the McGurk illusion, McGurk and Congruent primes with matching real-word auditory signals equivalently primed targets that were semantically related to the auditory signal, but not targets related to the McGurk percept. We conclude that the time course of auditory-visual integration is dependent on the lexicality of the auditory and visual input signals, and that listeners can lexically access one word and yet consciously perceive another.

  1. Audiovisual Integration of Speech in a Patient with Broca’s Aphasia

    Directory of Open Access Journals (Sweden)

    Tobias Søren Andersen

    2015-04-01

    Full Text Available Lesions to Broca’s area cause aphasia characterised by a severe impairment of the ability to speak, with comparatively intact speech perception. However, some studies have found effects on speech perception under adverse listening conditions, indicating that Broca’s area is also involved in speech perception. While these studies have focused on auditory speech perception other studies have shown that Broca’s area is activated by visual speech perception. Furthermore, one preliminary report found that a patient with Broca’s aphasia did not experience the McGurk illusion suggesting that an intact Broca’s area is necessary for audiovisual integration of speech. Here we describe a patient with Broca’s aphasia who experienced the McGurk illusion. This indicates that an intact Broca’s area is not necessary for audiovisual integration of speech. The McGurk illusions this patient experienced were atypical, which could be due to Broca’s area having a more subtle role in audiovisual integration of speech. The McGurk illusions of a control subject with Wernicke’s aphasia were, however, also atypical. This indicates that the atypical McGurk illusions were due to deficits in speech processing that are not specific to Broca’s aphasia.

  2. Audiovisual integration of speech in a patient with Broca's Aphasia.

    Science.gov (United States)

    Andersen, Tobias S; Starrfelt, Randi

    2015-01-01

    Lesions to Broca's area cause aphasia characterized by a severe impairment of the ability to speak, with comparatively intact speech perception. However, some studies have found effects on speech perception under adverse listening conditions, indicating that Broca's area is also involved in speech perception. While these studies have focused on auditory speech perception other studies have shown that Broca's area is activated by visual speech perception. Furthermore, one preliminary report found that a patient with Broca's aphasia did not experience the McGurk illusion suggesting that an intact Broca's area is necessary for audiovisual integration of speech. Here we describe a patient with Broca's aphasia who experienced the McGurk illusion. This indicates that an intact Broca's area is not necessary for audiovisual integration of speech. The McGurk illusions this patient experienced were atypical, which could be due to Broca's area having a more subtle role in audiovisual integration of speech. The McGurk illusions of a control subject with Wernicke's aphasia were, however, also atypical. This indicates that the atypical McGurk illusions were due to deficits in speech processing that are not specific to Broca's aphasia.

  3. Specialization in audiovisual speech perception: a replication study

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Andersen, Tobias

    of the speaker. Observers were required to report this after primary target categorization. We found a significant McGurk effect only in the natural speech and speech mode conditions supporting the finding of Tuomainen et al. Performance in the secondary task was similar in all conditions indicating......Speech perception is audiovisual as evidenced by bimodal integration in the McGurk effect. This integration effect may be specific to speech or be applied to all stimuli in general. To investigate this, Tuomainen et al. (2005) used sine-wave speech, which naïve observers may perceive as non-speech......, but hear as speech once informed of the linguistic origin of the signal. Combinations of sine-wave speech and incongruent video of the talker elicited a McGurk effect only for informed observers. This indicates that the audiovisual integration effect is specific to speech perception. However, observers...

  4. Specialization in audiovisual speech perception: a replication study

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Andersen, Tobias

    Speech perception is audiovisual as evidenced by bimodal integration in the McGurk effect. This integration effect may be specific to speech or be applied to all stimuli in general. To investigate this, Tuomainen et al. (2005) used sine-wave speech, which naïve observers may perceive as non-speech......, but hear as speech once informed of the linguistic origin of the signal. Combinations of sine-wave speech and incongruent video of the talker elicited a McGurk effect only for informed observers. This indicates that the audiovisual integration effect is specific to speech perception. However, observers...... of the speaker. Observers were required to report this after primary target categorization. We found a significant McGurk effect only in the natural speech and speech mode conditions supporting the finding of Tuomainen et al. Performance in the secondary task was similar in all conditions indicating...

  5. Audiovisual Integration of Speech in a Patient with Broca’s Aphasia

    DEFF Research Database (Denmark)

    Andersen, Tobias; Starrfelt, Randi

    2015-01-01

    Lesions to Broca's area cause aphasia characterized by a severe impairment of the ability to speak, with comparatively intact speech perception. However, some studies have found effects on speech perception under adverse listening conditions, indicating that Broca's area is also involved in speech...... perception. While these studies have focused on auditory speech perception other studies have shown that Broca's area is activated by visual speech perception. Furthermore, one preliminary report found that a patient with Broca's aphasia did not experience the McGurk illusion suggesting that an intact Broca......'s area is necessary for audiovisual integration of speech. Here we describe a patient with Broca's aphasia who experienced the McGurk illusion. This indicates that an intact Broca's area is not necessary for audiovisual integration of speech. The McGurk illusions this patient experienced were atypical...

  6. Proceedings of the DICE THROW Symposium 21-23 June 1977. Volume 3

    Science.gov (United States)

    1977-07-01

    OK(Z. COL Robert - SR1. GRANT. G. A. - Canada GREEN. Dale W. - WS* GUNBY, MAJ f. Neal - DNA GUPTA, Aaron - BRL GURKE, Gerhard - Germany HAYES, Bernard...Reekearch Corp. %󈨋N: Peter Brandt . EI.-:FX* ATTN: Gary Lang %TrN: Peter K. Pal, RI/.21h) IITS: R.K. Plehuch, RI/20!8 Ph’sics Internalional Com:pan.v...Iherhard Bachaann Ernst-Mach Institute Federal Republic of Germany AITNi Dr, lilvntt RwirIhenhbach ATTN: Gerhard Gurke Office of Test & Development

  7. Language as a Lacework of Layers, Including Visual Ones

    NARCIS (Netherlands)

    Neijt, A.H.; Smits, R.J.C.

    2014-01-01

    The so-called McGurk effect shows that synchronous information from visual and acoustic layers of information contributes to the perception of discrete categories, even where the actual physical auditory input is monotonous or gradual. Accepting a parallel architecture of language systems as propose

  8. Electrophysiological assessment of audiovisual integration in speech perception

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Dau, Torsten

    Speech perception integrates signal from ear and eye. This is witnessed by a wide range of audiovisual integration effects, such as ventriloquism and the McGurk illusion. Some behavioral evidence suggest that audiovisual integration of specific aspects is special for speech perception. However, o...

  9. Impact of Language on Development of Auditory-Visual Speech Perception

    Science.gov (United States)

    Sekiyama, Kaoru; Burnham, Denis

    2008-01-01

    The McGurk effect paradigm was used to examine the developmental onset of inter-language differences between Japanese and English in auditory-visual speech perception. Participants were asked to identify syllables in audiovisual (with congruent or discrepant auditory and visual components), audio-only, and video-only presentations at various…

  10. Audiovisual Speech Perception in Children with Developmental Language Disorder in Degraded Listening Conditions

    Science.gov (United States)

    Meronen, Auli; Tiippana, Kaisa; Westerholm, Jari; Ahonen, Timo

    2013-01-01

    Purpose: The effect of the signal-to-noise ratio (SNR) on the perception of audiovisual speech in children with and without developmental language disorder (DLD) was investigated by varying the noise level and the sound intensity of acoustic speech. The main hypotheses were that the McGurk effect (in which incongruent visual speech alters the…

  11. Auditory-Visual Speech Integration by Adults with and without Language-Learning Disabilities

    Science.gov (United States)

    Norrix, Linda W.; Plante, Elena; Vance, Rebecca

    2006-01-01

    Auditory and auditory-visual (AV) speech perception skills were examined in adults with and without language-learning disabilities (LLD). The AV stimuli consisted of congruent consonant-vowel syllables (auditory and visual syllables matched in terms of syllable being produced) and incongruent McGurk syllables (auditory syllable differed from…

  12. Audiovisual Perception of Congruent and Incongruent Dutch Front Vowels

    Science.gov (United States)

    Valkenier, Bea; Duyne, Jurriaan Y.; Andringa, Tjeerd C.; Baskent, Deniz

    2012-01-01

    Purpose: Auditory perception of vowels in background noise is enhanced when combined with visually perceived speech features. The objective of this study was to investigate whether the influence of visual cues on vowel perception extends to incongruent vowels, in a manner similar to the McGurk effect observed with consonants. Method:…

  13. Multisensory Speech Perception in Children with Autism Spectrum Disorders

    Science.gov (United States)

    Woynaroski, Tiffany G.; Kwakye, Leslie D.; Foss-Feig, Jennifer H.; Stevenson, Ryan A.; Stone, Wendy L.; Wallace, Mark T.

    2013-01-01

    This study examined unisensory and multisensory speech perception in 8-17 year old children with autism spectrum disorders (ASD) and typically developing controls matched on chronological age, sex, and IQ. Consonant-vowel syllables were presented in visual only, auditory only, matched audiovisual, and mismatched audiovisual ("McGurk")…

  14. Language as a Lacework of Layers, Including Visual Ones

    NARCIS (Netherlands)

    Neijt, A.H.; Smits, R.J.C.

    2014-01-01

    The so-called McGurk effect shows that synchronous information from visual and acoustic layers of information contributes to the perception of discrete categories, even where the actual physical auditory input is monotonous or gradual. Accepting a parallel architecture of language systems as

  15. Remote effects in real induction arrows

    Directory of Open Access Journals (Sweden)

    A. Ádám

    2002-06-01

    Full Text Available In August 2001, Annali di Geofisica, 44 (4, pp. 659-669, published the paper: «Anomalous directional behaviour of the real parts of the induction arrows in the Eastern Alps: tectonic and palaeogeographic implications» written by Marcus Gurk and Pierre-André Schnegg. Concerning this paper we have two brief comments.

  16. Perception of the Auditory-Visual Illusion in Speech Perception by Children with Phonological Disorders

    Science.gov (United States)

    Dodd, Barbara; McIntosh, Beth; Erdener, Dogu; Burnham, Denis

    2008-01-01

    An example of the auditory-visual illusion in speech perception, first described by McGurk and MacDonald, is the perception of [ta] when listeners hear [pa] in synchrony with the lip movements for [ka]. One account of the illusion is that lip-read and heard speech are combined in an articulatory code since people who mispronounce words respond…

  17. How prior expectations shape multisensory perception.

    Science.gov (United States)

    Gau, Remi; Noppeney, Uta

    2016-01-01

    The brain generates a representation of our environment by integrating signals from a common source, but segregating signals from different sources. This fMRI study investigated how the brain arbitrates between perceptual integration and segregation based on top-down congruency expectations and bottom-up stimulus-bound congruency cues. Participants were presented audiovisual movies of phonologically congruent, incongruent or McGurk syllables that can be integrated into an illusory percept (e.g. "ti" percept for visual «ki» with auditory /pi/). They reported the syllable they perceived. Critically, we manipulated participants' top-down congruency expectations by presenting McGurk stimuli embedded in blocks of congruent or incongruent syllables. Behaviorally, participants were more likely to fuse audiovisual signals into an illusory McGurk percept in congruent than incongruent contexts. At the neural level, the left inferior frontal sulcus (lIFS) showed increased activations for bottom-up incongruent relative to congruent inputs. Moreover, lIFS activations were increased for physically identical McGurk stimuli, when participants segregated the audiovisual signals and reported their auditory percept. Critically, this activation increase for perceptual segregation was amplified when participants expected audiovisually incongruent signals based on prior sensory experience. Collectively, our results demonstrate that the lIFS combines top-down prior (in)congruency expectations with bottom-up (in)congruency cues to arbitrate between multisensory integration and segregation.

  18. Audiovisual Speech Perception and Eye Gaze Behavior of Adults with Asperger Syndrome

    Science.gov (United States)

    Saalasti, Satu; Katsyri, Jari; Tiippana, Kaisa; Laine-Hernandez, Mari; von Wendt, Lennart; Sams, Mikko

    2012-01-01

    Audiovisual speech perception was studied in adults with Asperger syndrome (AS), by utilizing the McGurk effect, in which conflicting visual articulation alters the perception of heard speech. The AS group perceived the audiovisual stimuli differently from age, sex and IQ matched controls. When a voice saying /p/ was presented with a face…

  19. A Comparison of the Development of Audiovisual Integration in Children with Autism Spectrum Disorders and Typically Developing Children

    Science.gov (United States)

    Taylor, Natalie; Isaac, Claire; Milne, Elizabeth

    2010-01-01

    This study aimed to investigate the development of audiovisual integration in children with Autism Spectrum Disorder (ASD). Audiovisual integration was measured using the McGurk effect in children with ASD aged 7-16 years and typically developing children (control group) matched approximately for age, sex, nonverbal ability and verbal ability.…

  20. Decreased BOLD responses in audiovisual processing

    NARCIS (Netherlands)

    Wiersinga-Post, Esther; Tomaskovic, Sonja; Slabu, Lavinia; Renken, Remco; de Smit, Femke; Duifhuis, Hendrikus

    2010-01-01

    Audiovisual processing was studied in a functional magnetic resonance imaging study using the McGurk effect. Perceptual responses and the brain activity patterns were measured as a function of audiovisual delay. In several cortical and subcortical brain areas, BOLD responses correlated negatively wi

  1. Preference for Audiovisual Speech Congruency in Superior Temporal Cortex.

    Science.gov (United States)

    Lüttke, Claudia S; Ekman, Matthias; van Gerven, Marcel A J; de Lange, Floris P

    2016-01-01

    Auditory speech perception can be altered by concurrent visual information. The superior temporal cortex is an important combining site for this integration process. This area was previously found to be sensitive to audiovisual congruency. However, the direction of this congruency effect (i.e., stronger or weaker activity for congruent compared to incongruent stimulation) has been more equivocal. Here, we used fMRI to look at the neural responses of human participants during the McGurk illusion--in which auditory /aba/ and visual /aga/ inputs are fused to perceived /ada/--in a large homogenous sample of participants who consistently experienced this illusion. This enabled us to compare the neuronal responses during congruent audiovisual stimulation with incongruent audiovisual stimulation leading to the McGurk illusion while avoiding the possible confounding factor of sensory surprise that can occur when McGurk stimuli are only occasionally perceived. We found larger activity for congruent audiovisual stimuli than for incongruent (McGurk) stimuli in bilateral superior temporal cortex, extending into the primary auditory cortex. This finding suggests that superior temporal cortex prefers when auditory and visual input support the same representation.

  2. Audiovisual Perception of Congruent and Incongruent Dutch Front Vowels

    Science.gov (United States)

    Valkenier, Bea; Duyne, Jurriaan Y.; Andringa, Tjeerd C.; Baskent, Deniz

    2012-01-01

    Purpose: Auditory perception of vowels in background noise is enhanced when combined with visually perceived speech features. The objective of this study was to investigate whether the influence of visual cues on vowel perception extends to incongruent vowels, in a manner similar to the McGurk effect observed with consonants. Method:…

  3. Individual Differences in the Multisensory Temporal Binding Window Predict Susceptibility to Audiovisual Illusions

    Science.gov (United States)

    Stevenson, Ryan A.; Zemtsov, Raquel K.; Wallace, Mark T.

    2012-01-01

    Human multisensory systems are known to bind inputs from the different sensory modalities into a unified percept, a process that leads to measurable behavioral benefits. This integrative process can be observed through multisensory illusions, including the McGurk effect and the sound-induced flash illusion, both of which demonstrate the ability of…

  4. Multisensory Speech Perception in Children with Autism Spectrum Disorders

    Science.gov (United States)

    Woynaroski, Tiffany G.; Kwakye, Leslie D.; Foss-Feig, Jennifer H.; Stevenson, Ryan A.; Stone, Wendy L.; Wallace, Mark T.

    2013-01-01

    This study examined unisensory and multisensory speech perception in 8-17 year old children with autism spectrum disorders (ASD) and typically developing controls matched on chronological age, sex, and IQ. Consonant-vowel syllables were presented in visual only, auditory only, matched audiovisual, and mismatched audiovisual ("McGurk")…

  5. Audiovisual Speech Perception in Children with Developmental Language Disorder in Degraded Listening Conditions

    Science.gov (United States)

    Meronen, Auli; Tiippana, Kaisa; Westerholm, Jari; Ahonen, Timo

    2013-01-01

    Purpose: The effect of the signal-to-noise ratio (SNR) on the perception of audiovisual speech in children with and without developmental language disorder (DLD) was investigated by varying the noise level and the sound intensity of acoustic speech. The main hypotheses were that the McGurk effect (in which incongruent visual speech alters the…

  6. Dynamic Control of Light Emission Faster than the Lifetime Limit Using VO2 Phase-Change

    Science.gov (United States)

    2015-10-22

    phase- change Sébastien Cueff1,w, Dongfang Li1, You Zhou2, Franklin J. Wong2, Jonathan A. Kurvits1, Shriram Ramanathan2 & Rashid Zia1 Modulation is a...emission through modifications to the local density of optical states. Here, by leveraging the phase- change of a vanadium dioxide nanolayer, we...excited state lifetime. This proof-of-concept demonstration shows how integration with phase- change materials can transform wide- spread phosphorescent

  7. Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders.

    OpenAIRE

    Neasta, Jérémie; Ben Hamida, Sami; Yowell, Quinn; Carnicella, Sebastien; RON, DORIT

    2010-01-01

    Present adress of Sébastien Carnicella: Grenoble Institute of Neuroscience, Institut National de la Santé et de la Recherche Médicale U836, 38100 Grenoble, France. Equipe 10, Dynamique des réseaux neuronaux du mouvement; International audience; Alcohol addiction is a chronically relapsing disorder that includes certain maladaptive learning and memory. The serine and threonine kinase complex, mammalian target of rapamycin complex 1 (mTORC1), has been implicated in synaptic plasticity, learning...

  8. Marketingový mix luxusních značek v aplikaci na značku Moser

    OpenAIRE

    Křemenáková, Hana

    2015-01-01

    Subject of this bachelor thesis is marketing mix of glass manufactory Moser, a.s. Theoretical part deals with brand; STP; concept of marketing; marketing mix incl. marketing mix recommended by French authors J. N. Kapferer and V. Bastien for luxury brands; and SWOT analysis. Practical part introduces company Moser, a.s., incl. its applied marketing mix which is compared to marketing mix of luxury brands. Based on made comparison conclusions and recommendations are drawn.

  9. Two Nobel Prizes for five scientists – how superfluidity was discovered in a period of political upheaval

    CERN Multimedia

    Globe Info

    2011-01-01

    A public lecture by Sébastien Balibar, Director of Research at the CNRS and a member of the French Academy of Science. He directs the Laboratoire de Physique Statistique at the ENS in Paris. Thursday 13 October from 8:30 p.m. to 10:00 p.m. Globe de la science et de l’innovation Suitable for all – Admission free Number of places limited For further information: : +41 22 767 76 76  

  10. Optimal management of hemophilic arthropathy and hematomas

    OpenAIRE

    Lobet S; Hermans C; Lambert C.

    2014-01-01

    bastien Lobet,1,2 Cedric Hermans,1 Catherine Lambert1 1Hemostasis-Thrombosis Unit, Division of Hematology, 2Division of Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Brussels, Belgium Abstract: Hemophilia is a hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX. Its bleeding complications primarily affect the musculoskeletal system. Hemarthrosis is a major hemophilia-related complication, responsible ...

  11. EXECUTIVE COMMITTEE

    CERN Multimedia

    Association du personnel

    2010-01-01

    Composition 2010 Président :  Gianni DEROMA Vice-président :  Marcel AYMON Vice-président :  Sébastien EVRARD Secrétaire :  Michel GOOSSENS Trésorier :  Céline GROBON Membres :  Philippe DEFFERT  Roger GIRARDOT  Serge GRILLOT  Catherine LAVERRIERE  Michael LUDWIG  Sonia MALLON AMERIGO  Isabelle MARDIROSSIAN

  12. High Resolution Melting Analysis for fast and cheap polymorphism screening of marine populations

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Anne-Leila Meistertzheim, Isabelle Calves, Sébastien Artigaud, Carolyn S. Friedman, Christine Paillard, Jean Laroche & Claude Ferec ### Abstract This protocol permits the mutation scanning of PCR products by high-resolution DNA melting analysis requiring the inclusion of a saturating intercalating dye in the PCR mix without labelled probe. During a scanning process, fluorescent melting curves of PCR amplicons are analyzed. Mutations modifying melting curve shapes, are all...

  13. High Resolution Melting Analysis for fast and cheap polymorphism screening of marine populations

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Anne-Leila Meistertzheim, Isabelle Calves, Sébastien Artigaud, Carolyn S. Friedman, Christine Paillard, Jean Laroche & Claude Ferec ### Abstract This protocol permits the mutation scanning of PCR products by high-resolution DNA melting analysis requiring the inclusion of a saturating intercalating dye in the PCR mix without labelled probe. During a scanning process, fluorescent melting curves of PCR amplicons are analyzed. Mutations modifying melting curve shapes, are all...

  14. Atlas du Liban

    Directory of Open Access Journals (Sweden)

    Ramez Philippe Maalouf

    2008-11-01

    Full Text Available Compte-rendu de l’ouvrage Atlas du Liban: territoires et société, sous la direction d’Éric Verdeil, Ghaleb Faour et Sébastien Velut, édition franco-libanaise de l’IFPO (Institut Français du Proche-Orient et du CNRS Liban (Conseil National de la Recherche Scientifique – Liban, Beyrouth 2007.Resenha do livro Atlas du Liban: territoires et société, sob a direção de Éric Verdeil, Ghaleb Faour e Sébastien Velut, editado por iniciativa franco-libanesa do IFPO (Institut Français du Proche-Orient e pelo CNRS Liban (Conseil National de la Recherche Scientifique – Liban, Beirute, 2007.Review of Atlas du Liban: territoires et société, edited by Éric Verdeil, Ghaleb Faour and Sébastien Velut, french-lebanese edition by IFPO (Institut Français du Proche-Orient and CNRS Liban (Conseil National de la Recherche Scientifique – Liban Beirut, 2007.

  15. Multistage audiovisual integration of speech: dissociating identification and detection

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Tuomainen, Jyrki; Andersen, Tobias

    2011-01-01

    Speech perception integrates auditory and visual information. This is evidenced by the McGurk illusion where seeing the talking face influences the auditory phonetic percept and by the audiovisual detection advantage where seeing the talking face influences the detectability of the acoustic speech...... signal. Here we show that identification of phonetic content and detection can be dissociated as speech-specific and non-specific audiovisual integration effects. To this end, we employed synthetically modified stimuli, sine wave speech (SWS), which is an impoverished speech signal that only observers...... informed of its speech-like nature recognize as speech. While the McGurk illusion only occurred for informed observers the audiovisual detection advantage occurred for naïve observers as well. This finding supports a multi-stage account of audiovisual integration of speech in which the many attributes...

  16. The role of visual spatial attention in audiovisual speech perception

    DEFF Research Database (Denmark)

    Andersen, Tobias; Tiippana, K.; Laarni, J.

    2009-01-01

    integration did not change. Visual spatial attention was also able to select between the faces when lip reading. This suggests that visual spatial attention acts at the level of visual speech perception prior to audiovisual integration and that the effect propagates through audiovisual integration......Auditory and visual information is integrated when perceiving speech, as evidenced by the McGurk effect in which viewing an incongruent talking face categorically alters auditory speech perception. Audiovisual integration in speech perception has long been considered automatic and pre-attentive...... but recent reports have challenged this view. Here we study the effect of visual spatial attention on the McGurk effect. By presenting a movie of two faces symmetrically displaced to each side of a central fixation point and dubbed with a single auditory speech track, we were able to discern the influences...

  17. Multimodal integration in statistical learning

    DEFF Research Database (Denmark)

    Mitchell, Aaron; Christiansen, Morten Hyllekvist; Weiss, Dan

    2014-01-01

    Recent advances in the field of statistical learning have established that learners are able to track regularities of multimodal stimuli, yet it is unknown whether the statistical computations are performed on integrated representations or on separate, unimodal representations. In the present study......, we investigated the ability of adults to integrate audio and visual input during statistical learning. We presented learners with a speech stream synchronized with a video of a speaker’s face. In the critical condition, the visual (e.g., /gi/) and auditory (e.g., /mi/) signals were occasionally...... incongruent, which we predicted would produce the McGurk illusion, resulting in the perception of an audiovisual syllable (e.g., /ni/). In this way, we used the McGurk illusion to manipulate the underlying statistical structure of the speech streams, such that perception of these illusory syllables...

  18. Ordinal models of audiovisual speech perception

    DEFF Research Database (Denmark)

    Andersen, Tobias

    2011-01-01

    Audiovisual information is integrated in speech perception. One manifestation of this is the McGurk illusion in which watching the articulating face alters the auditory phonetic percept. Understanding this phenomenon fully requires a computational model with predictive power. Here, we describe...... ordinal models that can account for the McGurk illusion. We compare this type of models to the Fuzzy Logical Model of Perception (FLMP) in which the response categories are not ordered. While the FLMP generally fit the data better than the ordinal model it also employs more free parameters in complex...... experiments when the number of response categories are high as it is for speech perception in general. Testing the predictive power of the models using a form of cross-validation we found that ordinal models perform better than the FLMP. Based on these findings we suggest that ordinal models generally have...

  19. Proceedings of the DICE THROW Symposium 21-23 June 1977. Volume 1

    Science.gov (United States)

    1977-07-01

    Major Gerhard Zahlmann, and Robert A. Cole, U.S. Army Engineer Waterways Experiment Station. 15. AIRCRAFT SHELTER TESTS IN THE DICE TIHROW EVENT...BRL GURKE, Gerhard - Germany HAYES, Bernard - LLL HEGGIE, R. M. - Canada HEINTZEL, COL Hans-H. - Germany HUFF, William L. - WES HUGHES, Peter - NWEF...ATTN: Peter Brandt , L -2006 ATTN: Gar lang ATTN: Peter K. I-, 111/2170 ATTIN: R.k. Plebuch, R1/2078 Phsics International Compan> A[TN: Thomas G. Williams

  20. Individual Differences in the Multisensory Temporal Binding Window Predict Susceptibility to Audiovisual Illusions

    OpenAIRE

    Stevenson, Ryan A.; Raquel K Zemtsov; Wallace, Mark T.

    2012-01-01

    Human multisensory systems are known to bind inputs from the different sensory modalities into a unified percept, a process that leads to measurable behavioral benefits. This integrative process can be observed through multisensory illusions, including the McGurk effect and the sound-induced flash illusion, both of which demonstrate the ability of one sensory modality to modulate perception in a second modality. Such multisensory integration is highly dependent upon the temporal relationship ...

  1. Retrospective Study: Sleep, Mental Disorders, and TBI in Deployed Military Members

    Science.gov (United States)

    2014-12-06

    Wilk, J. E., Thomas, J. L., McGurk, D. M., Riviere, L. A., Castro, C. A., & Hoge, C. W. (2010). Mild traumatic brain injury ( concussion ) during...multiple cells . Comorbid substance use and adjustment disorders occurred the most frequently (18.2%), followed by substance use and mood disorders (16.3...sleep disorders had more comorbid anxiety disorders. Traumatic Brain Injury The first identified TBI diagnosis for each participant was used

  2. The function of consciousness in multisensory integration.

    Science.gov (United States)

    Palmer, Terry D; Ramsey, Ashley K

    2012-12-01

    The function of consciousness was explored in two contexts of audio-visual speech, cross-modal visual attention guidance and McGurk cross-modal integration. Experiments 1, 2, and 3 utilized a novel cueing paradigm in which two different flash suppressed lip-streams cooccured with speech sounds matching one of these streams. A visual target was then presented at either the audio-visually congruent or incongruent location. Target recognition differed for the congruent versus incongruent trials, and the nature of this difference depended on the probabilities of a target appearing at these respective locations. Thus, even though the lip-streams were never consciously perceived, they were nevertheless meaningfully integrated with the consciously perceived sounds, and participants learned to guide their attention according to statistical regularities between targets and these unconsciously perceived cross-modal cues. In Experiment 4, McGurk stimuli were presented in which the lip-streams were either flash suppressed (4a) or unsuppressed (4b), and the McGurk effect was found to vanish under conditions of flash suppression. Overall, these results suggest a simple yet fundamental principle regarding the function of consciousness in multisensory integration - cross-modal effects can occur in the absence of consciousness, but the influencing modality must be consciously perceived for its information to cross modalities.

  3. Modeling and analysis of real-time and embedded systems with UML and MARTE developing cyber-physical systems

    CERN Document Server

    Selic, Bran

    2013-01-01

    Modeling and Analysis of Real-Time and Embedded Systems with UML and MARTE explains how to apply the complex MARTE standard in practical situations. This approachable reference provides a handy user guide, illustrating with numerous examples how you can use MARTE to design and develop real-time and embedded systems and software. Expert co-authors Bran Selic and Sébastien Gérard lead the team that drafted and maintain the standard and give you the tools you need apply MARTE to overcome the limitations of cyber-physical systems. The functional sophistication required of modern cyber-physical

  4. Européanisation ou otanisation ?

    DEFF Research Database (Denmark)

    Schmitt, Olivier

    2015-01-01

    and the UK looked for doctrinal or technical answers to the challenges they were facing on the ground within NATO (the structure and/or the member states). However, the importation of such solutions depends on each national political-military context, in particular the proximity with the United States......, the existence of a strong local defense industry or a specific strategic culture. After the “Europeanisation without the EU” of the French defence policy in the 90’s identified by Bastien Irondelle, we now observe a “NATO-isation with NATO” of the three major European military powers’ defence policies, because...

  5. Editorial

    CERN Multimedia

    Staff Association

    2010-01-01

    New President and Executive Committee   In accordance with the Rules of the Staff Association, in December each year the Staff Council delegates elect a President who proposes a list of members of the Executive Committee. At its meeting on 7th December 2010, Staff Council elected by an overwhelming majority Michel Goossens and his Executive Committee for 2011, made up of eleven members and five permanently invited members.   Michel GOOSSENS IT Président Marcel AYMON HR Vice-président Sébastien ÉVRARD EN Vide-président Céline GROBON PH Trésorier Isabelle MARDIROSSIAN GS Secré...

  6. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

    OpenAIRE

    Valour F; Sénéchal A; Dupieux C; Karsenty J; Lustig S; Breton P; Gleizal A; Boussel L; Laurent F; Braun E; Chidiac C; Ader F; Ferry T

    2014-01-01

    Florent Valour,1–3 Agathe Sénéchal,1,2 Céline Dupieux,2–4 Judith Karsenty,1,2 Sébastien Lustig,2,5 Pierre Breton,2,6 Arnaud Gleizal,2,7 Loïc Boussel,2,8,9 Frédéric Laurent,2–4 Evelyne Braun,1 Christian Chidiac,1–3 Florence Ader,1–3 Tristan Ferry1–3 1Service des Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, Fra...

  7. Le corps à l'époque moderne

    Directory of Open Access Journals (Sweden)

    Ulrike Krampl

    2008-06-01

    Full Text Available GénéralitésAriès Philippe, Bejin André (dir., Sexualités occidentales, Paris, Seuil, 1982.Coenen Marie-Thérèse (dir., Corps de femmes, sexualité et contrôle social, Bruxelles, 2002.Comar Philippe, Les images du corps, Paris, Gallimard, « Découvertes », 1993.Cordier Pierre, Jahan Sébastien (dir., La blessure corporelle. Violences, souffrances, symboles et représentations, Poitiers, GERHICO, 2003.Le corps en morceaux, n° thématique de la revue Terrain, 18, mars 1992.Dauphin Cécile, Farge Arl...

  8. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

    OpenAIRE

    Valour F; Sénéchal A; Dupieux C; Karsenty J; Lustig S; Breton P; Gleizal A; Boussel L; Laurent F; Braun E; Chidiac C; Ader F; Ferry T

    2014-01-01

    Florent Valour,1–3 Agathe Sénéchal,1,2 Céline Dupieux,2–4 Judith Karsenty,1,2 Sébastien Lustig,2,5 Pierre Breton,2,6 Arnaud Gleizal,2,7 Loïc Boussel,2,8,9 Frédéric Laurent,2–4 Evelyne Braun,1 Christian Chidiac,1–3 Florence Ader,1–3 Tristan Ferry1–3 1Service des Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, Fra...

  9. Impact de la violence politique sur la santé mentale des jeunes adolescents en Colombie. Analyse des facteurs de risque et de protection

    OpenAIRE

    Sabatier, Colette; PALACIO SAÑUDO, JORGE ENRIQUE; Tousignant, Michel

    2011-01-01

    El objetivo de esta investigación es examinar desde una perspectiva ecológica la salud mental de los adolescentes desplazados por la violencia política en Colombia. Se tomó como base el modelo ecológico integrado del impacto del trauma de Elbedour, ten Bensel y Bastien (1993), que estipula la influencia combinada de diferentes niveles de factores unidos a la experiencia traumática, factores individuales y factores proximales que vienen de la familia, y de los factores sociales de la red socia...

  10. Nous remercions

    OpenAIRE

    2014-01-01

    Ruth Amossy Violaine Appel Aurélie Aubert Gloria Awad Julien Bertrand Aimé-Jules Bizimana Stephan Bratosin Philippe Braud Stéphane Cabrolié Dominique Cotte Alexandre Coutant Sébastien Couvrette Pierre De Senarciens Françoise Denoyelle Jean-Claude Deroubaix Guillaume Devin Jean-Pierre Esquenazi Patrick Eveno Sylvia Faure Jairo Ferreira François Foret Fanny Georges Laurent Gille Corinne Gobin Valérie Gorin Benoît Grevisse Jean Noël Kapferer Roselyne Koren Yves Krief Lylette Lacôte-Gabrysiak Pau...

  11. A Granulation "Flicker"-based Measure of Stellar Surface Gravity

    CERN Document Server

    Bastien, Fabienne A; Basri, Gibor; Pepper, Joshua

    2015-01-01

    In Bastien et al. (2013) we found that high quality light curves, such as those obtained by Kepler, may be used to measure stellar surface gravity via granulation-driven light curve "flicker". Here, we update and extend the relation originally presented in Bastien et al. (2013) after calibrating flicker against a more robust set of asteroseismically derived surface gravities. We describe in detail how we extract the flicker signal from the light curves, including how we treat phenomena, such as exoplanet transits and shot noise, that adversely affect the measurement of flicker. We examine the limitations of the technique, and, as a result, we now provide an updated treatment of the flicker-based logg error. We briefly highlight further applications of the technique, such as astrodensity profiling or its use in other types of stars with convective outer layers. We discuss potential uses in current and upcoming space-based photometric missions. Finally, we supply flicker-based logg values, and their uncertainti...

  12. CERN among the honours in the Geneva inter-company cross-country race

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    On 12 October, members of the CERN Running Club were yet again among the medals at the 33rd Cross Inter-Entreprises de Genève.   From left to right: Clément, Bastien, Olivier, Cédric, Erik and Mika. (Photo: Clément Bovet.) Teams comprising 3 to 4 runners from companies in the Geneva Canton competed in the 6-km race through the Parc des Evaux in Onex. Two of CERN’s teams made it into the medals in the Men’s category* -  Cédric, Mika, Guillaume and Clément came second, closely followed by their colleagues Olivier, Erik and Bastien, in third.  The next and last event of the year for the members of the Running Club will be the Escalade race, on 6-7 December. * The other categories are “Women” and “Mixed”. The full race results are available here and more photos from the event are available here.

  13. Sight and sound out of synch: fragmentation and renormalisation of audiovisual integration and subjective timing.

    Science.gov (United States)

    Freeman, Elliot D; Ipser, Alberta; Palmbaha, Austra; Paunoiu, Diana; Brown, Peter; Lambert, Christian; Leff, Alex; Driver, Jon

    2013-01-01

    The sight and sound of a person speaking or a ball bouncing may seem simultaneous, but their corresponding neural signals are spread out over time as they arrive at different multisensory brain sites. How subjective timing relates to such neural timing remains a fundamental neuroscientific and philosophical puzzle. A dominant assumption is that temporal coherence is achieved by sensory resynchronisation or recalibration across asynchronous brain events. This assumption is easily confirmed by estimating subjective audiovisual timing for groups of subjects, which is on average similar across different measures and stimuli, and approximately veridical. But few studies have examined normal and pathological individual differences in such measures. Case PH, with lesions in pons and basal ganglia, hears people speak before seeing their lips move. Temporal order judgements (TOJs) confirmed this: voices had to lag lip-movements (by ∼200 msec) to seem synchronous to PH. Curiously, voices had to lead lips (also by ∼200 msec) to maximise the McGurk illusion (a measure of audiovisual speech integration). On average across these measures, PH's timing was therefore still veridical. Age-matched control participants showed similar discrepancies. Indeed, normal individual differences in TOJ and McGurk timing correlated negatively: subjects needing an auditory lag for subjective simultaneity needed an auditory lead for maximal McGurk, and vice versa. This generalised to the Stream-Bounce illusion. Such surprising antagonism seems opposed to good sensory resynchronisation, yet average timing across tasks was still near-veridical. Our findings reveal remarkable disunity of audiovisual timing within and between subjects. To explain this we propose that the timing of audiovisual signals within different brain mechanisms is perceived relative to the average timing across mechanisms. Such renormalisation fully explains the curious antagonistic relationship between disparate timing

  14. Visual Distractors Disrupt Audiovisual Integration Regardless of Stimulus Complexity

    Science.gov (United States)

    Gibney, Kyla D.; Aligbe, Enimielen; Eggleston, Brady A.; Nunes, Sarah R.; Kerkhoff, Willa G.; Dean, Cassandra L.; Kwakye, Leslie D.

    2017-01-01

    The intricate relationship between multisensory integration and attention has been extensively researched in the multisensory field; however, the necessity of attention for the binding of multisensory stimuli remains contested. In the current study, we investigated whether diverting attention from well-known multisensory tasks would disrupt integration and whether the complexity of the stimulus and task modulated this interaction. A secondary objective of this study was to investigate individual differences in the interaction of attention and multisensory integration. Participants completed a simple audiovisual speeded detection task and McGurk task under various perceptual load conditions: no load (multisensory task while visual distractors present), low load (multisensory task while detecting the presence of a yellow letter in the visual distractors), and high load (multisensory task while detecting the presence of a number in the visual distractors). Consistent with prior studies, we found that increased perceptual load led to decreased reports of the McGurk illusion, thus confirming the necessity of attention for the integration of speech stimuli. Although increased perceptual load led to longer response times for all stimuli in the speeded detection task, participants responded faster on multisensory trials than unisensory trials. However, the increase in multisensory response times violated the race model for no and low perceptual load conditions only. Additionally, a geometric measure of Miller’s inequality showed a decrease in multisensory integration for the speeded detection task with increasing perceptual load. Surprisingly, we found diverging changes in multisensory integration with increasing load for participants who did not show integration for the no load condition: no changes in integration for the McGurk task with increasing load but increases in integration for the detection task. The results of this study indicate that attention plays a

  15. The effect of amblyopia on visual-auditory speech perception: why mothers may say "Look at me when I'm talking to you".

    Science.gov (United States)

    Burgmeier, Robert; Desai, Rajen U; Farner, Katherine C; Tiano, Benjamin; Lacey, Ryan; Volpe, Nicholas J; Mets, Marilyn B

    2015-01-01

    Children with a history of amblyopia, even if resolved, exhibit impaired visual-auditory integration and perceive speech differently. To determine whether a history of amblyopia is associated with abnormal visual-auditory speech integration. Retrospective observational study at an academic pediatric ophthalmologic clinic with an average of 4 years of follow-up. Participants were at least 3 years of age and without any history of neurologic or hearing disorders. Of 39 children originally in our study, 6 refused to participate. The remaining 33 participants completed the study. Twenty-four participants (mean [SD] age, 7.0 [1.5] years) had a history of amblyopia in 1 eye, with a visual acuity of at least 20/20 in the nonamblyopic eye. Nine controls (mean [SD] age, 8.0 [3.4] years) were recruited from referrals for visually insignificant etiologies or through preschool-screening eye examinations; all had 20/20 in both eyes. Participants were presented with a video demonstrating the McGurk effect (ie, a stimulus presenting an audio track playing the sound /pa/ and a separate video track of a person articulating /ka/). Normal visual-auditory integration produces the perception of hearing a fusion sound /ta/. Participants were asked to report which sound was perceived, /ka/, /pa/, or /ta/. Prevalence of perception of the fusion /ta/ sound. Prior to the study, amblyopic children were hypothesized to less frequently perceive /ta/. The McGurk effect was perceived by 11 of the 24 participants with amblyopia (45.8%) and all 9 controls (100%) (adjusted odds ratio, 22.3 [95% CI, 1.2-426.0]; P = .005). The McGurk effect was perceived by 100% of participants with amblyopia that was resolved by 5 years of age and by 100% of participants whose onset at amblyopia developed at or after 5 years of age. However, only 18.8% of participants with amblyopia that was unresolved by 5 years of age (n = 16) perceived the McGurk effect (adjusted odds ratio, 27.0 [95% CI, 1.1-654.0]; P = .02

  16. Multistage audiovisual integration of speech: dissociating identification and detection

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Tuomainen, Jyrki; Andersen, Tobias

    2011-01-01

    Speech perception integrates auditory and visual information. This is evidenced by the McGurk illusion where seeing the talking face influences the auditory phonetic percept and by the audiovisual detection advantage where seeing the talking face influences the detectability of the acoustic speech...... signal. Here we show that identification of phonetic content and detection can be dissociated as speech-specific and non-specific audiovisual integration effects. To this end, we employed synthetically modified stimuli, sine wave speech (SWS), which is an impoverished speech signal that only observers...

  17. Audiovisual integration in speech perception: a multi-stage process

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Tuomainen, Jyrki; Andersen, Tobias

    2011-01-01

    investigate whether the integration of auditory and visual speech observed in these two audiovisual integration effects are specific traits of speech perception. We further ask whether audiovisual integration is undertaken in a single processing stage or multiple processing stages.......Integration of speech signals from ear and eye is a well-known feature of speech perception. This is evidenced by the McGurk illusion in which visual speech alters auditory speech perception and by the advantage observed in auditory speech detection when a visual signal is present. Here we...

  18. Speech-specific audiovisual perception affects identification but not detection of speech

    DEFF Research Database (Denmark)

    Eskelund, Kasper; Andersen, Tobias

    -like nature of the signal. The sine-wave speech was dubbed onto congruent and incongruent video of a talking face. Tuomainen et al. found that the McGurk effect did not occur for naïve observers, but did occur when observers were informed. This indicates that the McGurk illusion is due to a mechanism...... of audiovisual integration specific to speech perception. However, the results of Tuomainen et al. might have been influenced by another effect. When observers were naïve, they had little motivation to look at the face. When informed, they knew that the face was relevant for the task and this could increase...... their motivation for looking at the face. Since Tuomainen et al. did not monitor eye-movements in their experiments the magnitude of the effect of motivation is unknown. The purpose of our first experiment was to replicate Tuomainen et al.’s findings while controlling observers’ eye movements using a secondary...

  19. Effect of attentional load on audiovisual speech perception: Evidence from ERPs

    Directory of Open Access Journals (Sweden)

    Agnès eAlsius

    2014-07-01

    Full Text Available Seeing articulatory movements influences perception of auditory speech. This is often reflected in a shortened latency of auditory event-related potentials (ERPs generated in the auditory cortex. The present study addressed whether this early neural correlate of audiovisual interaction is modulated by attention. We recorded ERPs in 15 subjects while they were presented with auditory, visual and audiovisual spoken syllables. Audiovisual stimuli consisted of incongruent auditory and visual components known to elicit a McGurk effect, i.e. a visually driven alteration in the auditory speech percept. In a Dual task condition, participants were asked to identify spoken syllables whilst monitoring a rapid visual stream of pictures for targets, i.e., they had to divide their attention. In a Single task condition, participants identified the syllables without any other tasks, i.e., they were asked to ignore the pictures and focus their attention fully on the spoken syllables. The McGurk effect was weaker in the Dual task than in the Single task condition, indicating an effect of attentional load on audiovisual speech perception. Early auditory ERP components, N1 and P2, peaked earlier to audiovisual stimuli than to auditory stimuli when attention was fully focused on syllables, indicating neurophysiological audiovisual interaction. This latency decrement was reduced when attention was loaded, suggesting that attention influences early neural processing of audiovisual speech. We conclude that reduced attention weakens the interaction between vision and audition in speech.

  20. Audiovisual Temporal Recalibration for Speech in Synchrony Perception and Speech Identification

    Science.gov (United States)

    Asakawa, Kaori; Tanaka, Akihiro; Imai, Hisato

    We investigated whether audiovisual synchrony perception for speech could change after observation of the audiovisual temporal mismatch. Previous studies have revealed that audiovisual synchrony perception is re-calibrated after exposure to a constant timing difference between auditory and visual signals in non-speech. In the present study, we examined whether this audiovisual temporal recalibration occurs at the perceptual level even for speech (monosyllables). In Experiment 1, participants performed an audiovisual simultaneity judgment task (i.e., a direct measurement of the audiovisual synchrony perception) in terms of the speech signal after observation of the speech stimuli which had a constant audiovisual lag. The results showed that the “simultaneous” responses (i.e., proportion of responses for which participants judged the auditory and visual stimuli to be synchronous) at least partly depended on exposure lag. In Experiment 2, we adopted the McGurk identification task (i.e., an indirect measurement of the audiovisual synchrony perception) to exclude the possibility that this modulation of synchrony perception was solely attributable to the response strategy using stimuli identical to those of Experiment 1. The characteristics of the McGurk effect reported by participants depended on exposure lag. Thus, it was shown that audiovisual synchrony perception for speech could be modulated following exposure to constant lag both in direct and indirect measurement. Our results suggest that temporal recalibration occurs not only in non-speech signals but also in monosyllabic speech at the perceptual level.

  1. Reduced audiovisual integration in synesthesia--evidence from bimodal speech perception.

    Science.gov (United States)

    Sinke, Christopher; Neufeld, Janina; Zedler, Markus; Emrich, Hinderk M; Bleich, Stefan; Münte, Thomas F; Szycik, Gregor R

    2014-03-01

    Recent research suggests synesthesia as a result of a hypersensitive multimodal binding mechanism. To address the question whether multimodal integration is altered in synesthetes in general, grapheme-colour and auditory-visual synesthetes were investigated using speech-related stimulation in two behavioural experiments. First, we used the McGurk illusion to test the strength and number of illusory perceptions in synesthesia. In a second step, we analysed the gain in speech perception coming from seen articulatory movements under acoustically noisy conditions. We used disyllabic nouns as stimulation and varied signal-to-noise ratio of the auditory stream presented concurrently to a matching video of the speaker. We hypothesized that if synesthesia is due to a general hyperbinding mechanism this group of subjects should be more susceptible to McGurk illusions and profit more from the visual information during audiovisual speech perception. The results indicate that there are differences between synesthetes and controls concerning multisensory integration--but in the opposite direction as hypothesized. Synesthetes showed a reduced number of illusions and had a reduced gain in comprehension by viewing matching articulatory movements in comparison to control subjects. Our results indicate that rather than having a hypersensitive binding mechanism, synesthetes show weaker integration of vision and audition. © 2012 The British Psychological Society.

  2. Effect of attentional load on audiovisual speech perception: evidence from ERPs.

    Science.gov (United States)

    Alsius, Agnès; Möttönen, Riikka; Sams, Mikko E; Soto-Faraco, Salvador; Tiippana, Kaisa

    2014-01-01

    Seeing articulatory movements influences perception of auditory speech. This is often reflected in a shortened latency of auditory event-related potentials (ERPs) generated in the auditory cortex. The present study addressed whether this early neural correlate of audiovisual interaction is modulated by attention. We recorded ERPs in 15 subjects while they were presented with auditory, visual, and audiovisual spoken syllables. Audiovisual stimuli consisted of incongruent auditory and visual components known to elicit a McGurk effect, i.e., a visually driven alteration in the auditory speech percept. In a Dual task condition, participants were asked to identify spoken syllables whilst monitoring a rapid visual stream of pictures for targets, i.e., they had to divide their attention. In a Single task condition, participants identified the syllables without any other tasks, i.e., they were asked to ignore the pictures and focus their attention fully on the spoken syllables. The McGurk effect was weaker in the Dual task than in the Single task condition, indicating an effect of attentional load on audiovisual speech perception. Early auditory ERP components, N1 and P2, peaked earlier to audiovisual stimuli than to auditory stimuli when attention was fully focused on syllables, indicating neurophysiological audiovisual interaction. This latency decrement was reduced when attention was loaded, suggesting that attention influences early neural processing of audiovisual speech. We conclude that reduced attention weakens the interaction between vision and audition in speech.

  3. Hearing (Rivaling Lips and Seeing Voices: How Audiovisual Interactions Modulate Perceptual Stabilization in Binocular Rivalry

    Directory of Open Access Journals (Sweden)

    Manuel eVidal

    2014-09-01

    Full Text Available In binocular rivalry (BR, sensory input remains the same yet subjective experience fluctuates irremediably between two mutually exclusive representations. We investigated the perceptual stabilization effect of an additional sound on the BR dynamics using speech stimuli known to involve robust audiovisual (AV interactions at several cortical levels. Subjects sensitive to the McGurk effect were presented looping videos of rivaling faces uttering /aba/ and /aga/ respectively, while synchronously hearing the voice /aba/. They reported continuously the dominant percept, either observing passively or trying actively to promote one of the faces. The few studies that investigated the influence of information from an external modality on perceptual competition reported results that seem at first sight inconsistent. Since these differences could stem from how well the modalities matched, we addressed this by comparing two levels of AV congruence: real (/aba/ viseme vs. illusory (/aga/ viseme producing the /ada/ McGurk fusion. First, adding the voice /aba/ stabilized both real and illusory congruent lips percept. Second, real congruence of the added voice improved volitional control whereas illusory congruence did not, suggesting a graded contribution to the top-down sensitivity control of selective attention. In conclusion, a congruent sound enhanced considerably attentional control over the perceptual outcome selection; however, differences between passive stabilization and active control according to AV congruency suggest these are governed by two distinct mechanisms. Based on existing theoretical models of BR, selective attention and AV interaction in speech perception, we provide a general interpretation of our findings.

  4. Arrested Development of Audiovisual Speech Perception in Autism Spectrum Disorders

    Science.gov (United States)

    Stevenson, Ryan A.; Siemann, Justin K.; Woynaroski, Tiffany G.; Schneider, Brittany C.; Eberly, Haley E.; Camarata, Stephen M.; Wallace, Mark T.

    2013-01-01

    Atypical communicative abilities are a core marker of Autism Spectrum Disorders (ASD). A number of studies have shown that, in addition to auditory comprehension differences, individuals with autism frequently show atypical responses to audiovisual speech, suggesting a multisensory contribution to these communicative differences from their typically developing peers. To shed light on possible differences in the maturation of audiovisual speech integration, we tested younger (ages 6-12) and older (ages 13-18) children with and without ASD on a task indexing such multisensory integration. To do this, we used the McGurk effect, in which the pairing of incongruent auditory and visual speech tokens typically results in the perception of a fused percept distinct from the auditory and visual signals, indicative of active integration of the two channels conveying speech information. Whereas little difference was seen in audiovisual speech processing (i.e., reports of McGurk fusion) between the younger ASD and TD groups, there was a significant difference at the older ages. While TD controls exhibited an increased rate of fusion (i.e., integration) with age, children with ASD failed to show this increase. These data suggest arrested development of audiovisual speech integration in ASD. The results are discussed in light of the extant literature and necessary next steps in research. PMID:24218241

  5. Multisensory Illusions and the Temporal Binding Window

    Directory of Open Access Journals (Sweden)

    Ryan A Stevenson

    2011-10-01

    Full Text Available The ability of our sensory systems to merge sensory information from distinct modalities is remarkable. One stimulus characteristic utilized in this operation is temporal coincidence. Auditory and visual information are integrated within a narrow range of temporal offsets, known as the temporal binding window (TBW, which varies between individuals, stimulus type, and task. In this series of experiments, we assessed the relationship within individuals between the width of their TBW and their ability to integrate audiovisual information. The TBW was measured through a perceived subjective simultaneity task. In conjunction with this, we measured each individual's ability to integrate auditory and visual information with two multisensory illusions, the McGurk effect and Flashbeep illusion. The results from these studies demonstrate that the TBW is highly correlated with the individual's ability to integrate. These relationships were seen in only the right TBW, in which visual presentations preceded auditory presentations, a finding that is ecologically logical. However, differences were seen between the two illusory conditions, where the McGurk effect was stronger in individuals with narrow TBWs, again, an ecologically logical finding. The opposite relationship was seen with flashbeep illusion, possibly due to inherent asynchronies in the illusion.

  6. The Multisensory Temporal Binding Window: Perceptual Fusion, Training, and Autism

    Directory of Open Access Journals (Sweden)

    Ryan A Stevenson

    2011-10-01

    Full Text Available The process of integrating information across sensory modalities is highly dependent upon the temporal coincidence of the inputs. Audiovisual information is integrated within a range of temporal offsets, known as the temporal binding window (TBW, which varies between individuals. Three particular findings relating to TBW have led us to a novel approach to address sensory integration impairments in children with autism. The first is that autistic children have an atypically wide TBW, as measured through manipulations of audiovisual illusions. Second, an individual's TBW is related to their ability to perceptually fuse audiovisual inputs, particularly as seen in the McGurk effect; the narrower the right TBW, the stronger the McGurk effect. The third finding is that the TBW is plastic. Through perceptual feedback training, our lab showed that individuals' right TBW can be narrowed. These three findings, which we will present, lead to a study of perceptual feedback training in autistic children, who may have the ability to narrow their TBW, with a possible positive impact on their ability to integrate multisensory information, specifically speech. We will conclude with the presentation of behavioral and electrophysiological data illustrating an atypical relationship between the TBW and perceptual fusion in ASD.

  7. Une archéologie responsable

    Directory of Open Access Journals (Sweden)

    Christian Sapin

    2010-02-01

    Full Text Available À la suite de plusieurs découvertes en milieu urbain, ces vingt dernières années, de nouveaux sites religieux connus par les sources, comme celui de Luxeuil ou ignorés de celles-ci comme la basilique funéraire de la Rue Maraval à Marseille, nous avons souhaité avec Sébastien Bully, réfléchir à partir d’études de cas, sur les choix qui ont pu être faits ou qui peuvent être faits pour conserver in situ des témoignages souvent rares si ce n’est exceptionnels.  Nous sommes loin de l’époque où l’a...

  8. Aspects de la domestication sociale de la beauté

    Directory of Open Access Journals (Sweden)

    Pierre-Joseph Laurent

    2011-03-01

    Full Text Available Je voudrais remercier Danielle Bastien pour nos nombreux échanges sur les hypothèses présentées dans ce texte, ainsi que Jacinthe Mazzocchetti et Mike Singleton pour leurs relectures critiques. Je remercie également les membres du LAAP de m’avoir encouragé à poursuivre ce travail difficile et parsemé d’embuches.S’intéresser à l’inégale répartition de la beauté humaine équivaut à valoriser les singularités, mais aussi les disparités existant entre les individus alors que les militants antiraci...

  9. A new batch of CERN apprentices

    CERN Multimedia

    Anaïs Schaeffer

    2011-01-01

    This year CERN is once again hosting six electronics and physics lab apprentices. Over the coming four years they will learn the fundamentals of their trade under the expert eye of experienced CERN professionals.   From left to right: Eugénie Gallay, Adrien Tambasco, Bastien Ray, Frederika De Jaegere, Luca Fazzone and Loïc Garcia, the six apprentices who have just left CERN, having passed their diplomas. Jean-Marc Bouché is pictured behind them. The selection process is long and arduous. Every year, up to 150 candidates between the ages of 15 and 21 apply for the specialised sandwich courses in mechatronics offered by Geneva's Office pour l’orientation, la formation professionnelle et continue in partnership with the Geneva Industrial Union. Only a handful of those specialising in electronics and physics laboratory techniques – with strong applications and even stronger motivation – will be fortunate enough to work...

  10. Entretien avec Linda Boukhris

    Directory of Open Access Journals (Sweden)

    Sébastien Jacquot

    2012-02-01

    Full Text Available Linda Boukhris est Doctorante en géographie, EIREST - Université Paris 1 Panthéon - Sorbonne et consultante dans un cabinet de conseil en management. - Maria Gravari-Barbas (MGB, Sébastien Jacquot (SJ. Quel a été votre parcours de géographe, avant le début de votre thèse ?- Linda Boukhris (LB. Après un baccalauréat littéraire, j’ai réalisé trois années de classe préparatoire littéraire au Lycée Lakanal à Sceaux (hypokhâgne, khâgne, cube dans le but de préparer le concours de l’École Norma...

  11. And now, for the winners.

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The Computer Security Day held on 10 June was a success. There were eight presentations, with some forty people attending each session.     The presentation videos can be viewed on Indico. The computer security team’s new website is now up and running, with a wealth of useful information and advice. Go to http://cern.ch/Computer.Security.     The quiz attracted 130 participants, and the answers have now been posted on line! The quiz winners are: Lars Aprin, Richard Baud, Thibaut Bernard, Brice Copy, Daniele de Ruschi, Sébastien Gadrat, Amanda Garcia Munoz, Stephen Gowdy, Joni Hahkala, Joseph Izen, Ryszard Erazm Jurga, Jukka Klem, Danila Oleynik, Ian Pong, Pascal Serge Roguet, Jani Tapani Taskinen, Jan Therhaag, Yves Thurel, Adrian Vogel, Thomas White. Well done to all! If you haven’t done so already, you should soon be getting your prize (i.e. a book, a T-shirt or a bag, etc.).  

  12. Examining the Flicker-Jitter Relation of K2 stars: the Dependence on Chromospheric Activity

    Science.gov (United States)

    Luhn, Jacob K.; Bastien, Fabienne A.; Wright, Jason

    2017-01-01

    Recently, Bastien et al. (2014) have shown that short timescale photometric variations from high-precision Kepler light curves, coined "flicker", can be linked to radial velocity (RV) noise, or "jitter", in chromospherically inactive stars. Observations of the sun show invariance in flicker over its 11-year activity cycle. Therefore, we seek to examine how well the relation holds for more active stars. Here we explore the relation between photometric flicker and RV jitter by extending the sample to stars observed by the recent K2 mission for which data have been released (Campaigns 0-8). The initial Kepler sample included 12 stars with surface gravities 3 TESS and other future telescopes which will produce high-precision light curves.

  13. Processing of audiovisually congruent and incongruent speech in school-age children with a history of specific language impairment: a behavioral and event-related potentials study.

    Science.gov (United States)

    Kaganovich, Natalya; Schumaker, Jennifer; Macias, Danielle; Gustafson, Dana

    2015-09-01

    Previous studies indicate that at least some aspects of audiovisual speech perception are impaired in children with specific language impairment (SLI). However, whether audiovisual processing difficulties are also present in older children with a history of this disorder is unknown. By combining electrophysiological and behavioral measures, we examined perception of both audiovisually congruent and audiovisually incongruent speech in school-age children with a history of SLI (H-SLI), their typically developing (TD) peers, and adults. In the first experiment, all participants watched videos of a talker articulating syllables 'ba', 'da', and 'ga' under three conditions - audiovisual (AV), auditory only (A), and visual only (V). The amplitude of the N1 (but not of the P2) event-related component elicited in the AV condition was significantly reduced compared to the N1 amplitude measured from the sum of the A and V conditions in all groups of participants. Because N1 attenuation to AV speech is thought to index the degree to which facial movements predict the onset of the auditory signal, our findings suggest that this aspect of audiovisual speech perception is mature by mid-childhood and is normal in the H-SLI children. In the second experiment, participants watched videos of audivisually incongruent syllables created to elicit the so-called McGurk illusion (with an auditory 'pa' dubbed onto a visual articulation of 'ka', and the expectant perception being that of 'ta' if audiovisual integration took place). As a group, H-SLI children were significantly more likely than either TD children or adults to hear the McGurk syllable as 'pa' (in agreement with its auditory component) than as 'ka' (in agreement with its visual component), suggesting that susceptibility to the McGurk illusion is reduced in at least some children with a history of SLI. Taken together, the results of the two experiments argue against global audiovisual integration impairment in children with a

  14. Can expectation enhance response to suggestion? De-automatization illuminates a conundrum.

    Science.gov (United States)

    Lifshitz, Michael; Howells, Catherine; Raz, Amir

    2012-06-01

    Disparate theoretical viewpoints construe hypnotic suggestibility either as a stable trait, largely determined by underlying cognitive aptitude, or as a flexible skill amenable to attitudinal factors including beliefs and expectations. Circumscribed findings support both views. The present study attempted to consolidate these orthogonal perspectives through the lens of expectancy modification. We surreptitiously controlled light and sound stimuli to convince participants that they were responding strongly to hypnotic suggestions for visual and auditory hallucinations. Extending our previous findings, we indexed hypnotic suggestibility by de-automatizing an involuntary audiovisual phenomenon-the McGurk effect. Here we show that, regardless of expectancy modification, the experimental procedure led to heightened expectations concerning future hypnotic response. We found little effect of expectation, however, on actual response to suggestion. Our findings intimate that, at least in the present experimental context, expectation hardly correlates with--and is unlikely to be a primary determinant of--high hypnotic suggestibility.

  15. A sex difference in visual influence on heard speech.

    Science.gov (United States)

    Irwin, Julia R; Whalen, D H; Fowler, Carol A

    2006-05-01

    Reports of sex differences in language processing are inconsistent and are thought to vary by task type and difficulty. In two experiments, we investigated a sex difference in visual influence onheard speech (the McGurk effect). First, incongruent consonant-vowel stimuli were presented where the visual portion of the signal was brief (100 msec) or full (temporally equivalent to the auditory). Second, to determine whether men and women differed in their ability to extract visual speech information from these brief stimuli, the same stimuli were presented to new participants with an additional visual-only (lipread) condition. In both experiments, women showed a significantly greater visual influence on heard speech than did men for the brief visual stimuli. No sex differences for the full stimuli or in the ability to lipread were found. These findings indicate that the more challenging brief visual stimuli elicit sex differences in the processing of audiovisual speech.

  16. Children use visual speech to compensate for non-intact auditory speech.

    Science.gov (United States)

    Jerger, Susan; Damian, Markus F; Tye-Murray, Nancy; Abdi, Hervé

    2014-10-01

    We investigated whether visual speech fills in non-intact auditory speech (excised consonant onsets) in typically developing children from 4 to 14 years of age. Stimuli with the excised auditory onsets were presented in the audiovisual (AV) and auditory-only (AO) modes. A visual speech fill-in effect occurs when listeners experience hearing the same non-intact auditory stimulus (e.g., /-b/ag) as different depending on the presence/absence of visual speech such as hearing /bag/ in the AV mode but hearing /ag/ in the AO mode. We quantified the visual speech fill-in effect by the difference in the number of correct consonant onset responses between the modes. We found that easy visual speech cues /b/ provided greater filling in than difficult cues /g/. Only older children benefited from difficult visual speech cues, whereas all children benefited from easy visual speech cues, although 4- and 5-year-olds did not benefit as much as older children. To explore task demands, we compared results on our new task with those on the McGurk task. The influence of visual speech was uniquely associated with age and vocabulary abilities for the visual speech fill--in effect but was uniquely associated with speechreading skills for the McGurk effect. This dissociation implies that visual speech--as processed by children-is a complicated and multifaceted phenomenon underpinned by heterogeneous abilities. These results emphasize that children perceive a speaker's utterance rather than the auditory stimulus per se. In children, as in adults, there is more to speech perception than meets the ear. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Timing in audiovisual speech perception: A mini review and new psychophysical data.

    Science.gov (United States)

    Venezia, Jonathan H; Thurman, Steven M; Matchin, William; George, Sahara E; Hickok, Gregory

    2016-02-01

    Recent influential models of audiovisual speech perception suggest that visual speech aids perception by generating predictions about the identity of upcoming speech sounds. These models place stock in the assumption that visual speech leads auditory speech in time. However, it is unclear whether and to what extent temporally-leading visual speech information contributes to perception. Previous studies exploring audiovisual-speech timing have relied upon psychophysical procedures that require artificial manipulation of cross-modal alignment or stimulus duration. We introduce a classification procedure that tracks perceptually relevant visual speech information in time without requiring such manipulations. Participants were shown videos of a McGurk syllable (auditory /apa/ + visual /aka/ = perceptual /ata/) and asked to perform phoneme identification (/apa/ yes-no). The mouth region of the visual stimulus was overlaid with a dynamic transparency mask that obscured visual speech in some frames but not others randomly across trials. Variability in participants' responses (~35 % identification of /apa/ compared to ~5 % in the absence of the masker) served as the basis for classification analysis. The outcome was a high resolution spatiotemporal map of perceptually relevant visual features. We produced these maps for McGurk stimuli at different audiovisual temporal offsets (natural timing, 50-ms visual lead, and 100-ms visual lead). Briefly, temporally-leading (~130 ms) visual information did influence auditory perception. Moreover, several visual features influenced perception of a single speech sound, with the relative influence of each feature depending on both its temporal relation to the auditory signal and its informational content.

  18. Subdural porous and notched mini-grid electrodes for wireless intracranial electroencephalographic recordings

    Directory of Open Access Journals (Sweden)

    Salam MT

    2014-12-01

    Full Text Available Muhammad Tariqus Salam,1 Sébastien Gélinas,1 Sébastien Desgent,2 Sandra Duss,2 Félix Bernier Turmel,1,3 Lionel Carmant,2 Mohamad Sawan,1 Dang Khoa Nguyen3 1Polystim Neurotechnologies Laboratory, Polytechnique Montréal, QC, Canada; 2Research Center, Sainte-Justine University Hospital Center (CHU Sainte-Justine, Université de Montréal, QC, Canada; 3Neurology Service, Department of Medicine, Notre-Dame Hospital, Centre Hospitalier de l'Université de Montréal (CHUM, QC, Canada Background: Intracranial electroencephalography (EEG studies are widely used in the presurgical evaluation of drug-refractory patients with partial epilepsy. Because chronic implantation of intracranial electrodes carries a risk of infection, hemorrhage, and edema, it is best to limit the number of electrodes used without compromising the ability to localize the epileptogenic zone (EZ. There is always a risk that an intracranial study may fail to identify the EZ because of suboptimal coverage. We present a new subdural electrode design that will allow better sampling of suspected areas of epileptogenicity with lower risk to patients. Method: Impedance of the proposed electrodes was characterized in vitro using electrochemical impedance spectroscopy. The appearance of the novel electrodes on magnetic resonance imaging (MRI was tested by placing the electrodes into a gel solution (0.9% NaCl with 14 g gelatin. In vivo neural recordings were performed in male Sprague Dawley rats. Performance comparisons were made using microelectrode recordings from rat cortex and subdural/depth recordings from epileptic patients. Histological examinations of rat brain after 3-week icEEG intracerebral electroencephalography (icEEG recordings were performed. Results: The in vitro results showed minimum impedances for optimum choice of pure gold materials for electrode contacts and wire. Different attributes of the new electrodes were identified on MRI. The results of in vivo recordings

  19. Larger Planet Radii Inferred from Stellar "Flicker" Brightness Variations of Bright Planet Host Stars

    CERN Document Server

    Bastien, Fabienne A; Pepper, Joshua

    2014-01-01

    Most extrasolar planets have been detected by their influence on their parent star, typically either gravitationally (the Doppler method) or by the small dip in brightness as the planet blocks a portion of the star (the transit method). Therefore, the accuracy with which we know the masses and radii of extrasolar planets depends directly on how well we know those of the stars, the latter usually determined from the measured stellar surface gravity, logg. Recent work has demonstrated that the short-timescale brightness variations ("flicker") of stars can be used to measure logg to a high accuracy of ~0.1-0.2 dex (Bastien et al. 2013). Here, we use flicker measurements of 289 bright (Kepmag<13) candidate planet-hosting stars with Teff=4500-6650 K to re-assess the stellar parameters and determine the resulting impact on derived planet properties. This re-assessment reveals that for the brightest planet-host stars, an astrophysical bias exists that contaminates the stellar sample with evolved stars: nearly 50%...

  20. Design de sistemas de informação centrado no usuário e a abordagem do sense-making

    Directory of Open Access Journals (Sweden)

    Edmeire Cristina Pereira

    Full Text Available Esta pesquisa analisa alguns aspectos da interação ser humano-computador e da abordagem do Sense-Making (Dervin e outros, também reconhecida na literatura como "abordagem centrada no usuário" ou, ainda, "abordagem da percepção do usuário". Examina um site de uma empresa carioca (Rio de Janeiro, Brasil do setor de farmácia, cosméticos e perfumaria, levando-se em consideração o lay-out das sucessivas telas com janelas, menus, botões, ícones e todos os componentes do sistema visíveis para o usuário. Como resultado das análises do conteúdo das páginas, da comunicação visual e de sua interatividade com os usuários potenciais, evidencia-se que o site não atende a todos os critérios de qualidade sugeridos pela literatura e, nem tampouco, a todas as diretrizes básicas para o design de sistemas de informação centrado no usuário, por Schneiderman e Bastien & Scapin.

  1. L.J. van der Veen et S. Bodinga-bwa-Bodinga. Gedandedi sa Geviya/ Dictionnaire Geviya?Fran?ais

    Directory of Open Access Journals (Sweden)

    P.A. Mavoungou

    2011-10-01

    Full Text Available La parution aux ?ditions Peeters de l'ouvrage de r?f?rence lexicographique intitul? Gedandedi sa Geviya/Dictionnaire Geviya?Fran?ais (en abr?g? DGF dans les reste de l'article a ?t? accueilli avec joie et fiert? aussi bien par les locuteurs geviya1 en particulier que par les Gabonais en g?n?ral. Ce dictionnaire, r?sultat d'une longue et fructueuse collaboration scientifique entre Lolke van der Veen et S?bastien Bodinga-bwa-Bodinga, marque le d?but d'une nouvelle ?re dans la r?daction des dictionnaires au Gabon. En effet, la majorit? des ouvrages de r?f?rence lexicographique disponibles dans les langues gabonaises sont des dictionnaires bilingues r?dig?s par les missionnaires catholiques et protestants ou par les administrateurs coloniaux dans la p?riode allant de 1800 ? 1960, date de l'accession du Gabon ? la souverainet? internationale (Nyangone Assam et Mavoungou 2000, Mavoungou 2001.

  2. Optimal management of hemophilic arthropathy and hematomas

    Directory of Open Access Journals (Sweden)

    Lobet S

    2014-10-01

    Full Text Available Sébastien Lobet,1,2 Cedric Hermans,1 Catherine Lambert1 1Hemostasis-Thrombosis Unit, Division of Hematology, 2Division of Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Brussels, Belgium Abstract: Hemophilia is a hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX. Its bleeding complications primarily affect the musculoskeletal system. Hemarthrosis is a major hemophilia-related complication, responsible for a particularly debilitating chronic arthropathy, in the long term. In addition to clotting factor concentrates, usually prescribed by the hematologist, managing acute hemarthrosis and chronic arthropathy requires a close collaboration between the orthopedic surgeon and physiotherapist. This collaboration, comprising a coagulation and musculoskeletal specialist, is key to effectively preventing hemarthrosis, managing acute joint bleeding episodes, assessing joint function, and actively treating chronic arthropathy. This paper reviews, from a practical point of view, the pathophysiology, clinical manifestations, and treatment of hemarthrosis and chronic hemophilia-induced arthropathy for hematologists, orthopedic surgeons, and physiotherapists. Keywords: hemophilia, arthropathy, hemarthrosis, hematoma, physiotherapy, target joint

  3. Tomographic reconstruction of structures using a novel GPR system

    Science.gov (United States)

    Fedeli, Alessandro; Ježová, Jana; Lambot, Sébastien; Pastorino, Matteo; Randazzo, Andrea; Pajewski, Lara

    2017-04-01

    The ever growing range of applications of ground penetrating radar (GPR) motivates the need of developing efficient measurement systems combined with effective data processing methods. On the one hand, advanced GPR measurement systems require to accurately model the physical effects occurring between the antenna structure and the medium. On the other hand, the GPR device should provide a reliable reconstruction of the properties of the targets under an inspection to a common user. In this work, a novel GPR system was tested for the imaging of buried structures. First of all, the acquired experimental data were pre-processed with a proper calibration technique for removing antenna effects. After that, a reconstruction of a hidden structure was obtained by means of both qualitative and quantitative electromagnetic inverse scattering methods. In particular, while the qualitative techniques aim at reconstructing only specific features of the targets (e.g., location, shape), the proposed quantitative method has the challenging goal of the complete electromagnetic characterization of the buried structures. The performance of the new system was evaluated in different operating conditions with promising results. Acknowledgment This work benefited from the networking activities within the EU funded COST Action TU1208, "Civil Engineering Applications of Ground Penetrating Radar". Part of this work was carried out during the Short-Term Scientific Mission STSM-TU1208-34990 "Testing of a new lightweight radar system for tomographical reconstruction of circular structures" (Alessandro Fedeli, Italy, visiting Prof. Sébastien Lambot, Belgium).

  4. Plastic is fantastic!

    CERN Multimedia

    2006-01-01

    The CERN TS/MME Group's polymer workshop assists the accelerators and experiments in drawing up specifications, producing prototypes and making limited or special series of polymer parts. Jean-François Ecarnot and Sébastien Clément, the CERN polymer laboratory's two technicians. Making polymer components is a bit like making bread. Just add a hardening agent and other processing agents to the resin, mix well, de-gas to remove the air, then cook in ovens bearing a striking resemblance to bread ovens and they're ready! The recipe is somewhat more complicated in practice. CERN's polymer experts have special knowledge and skills enabling them to find and adapt polymers and glues in order to resolve the toughest problems the components of the accelerators and experiments can throw at them. The CERN polymer workshop (TS Department, MME Group) responds to highly specific requests. It provides advice, makes prototypes and draws up specifications for items that are subsequently produced by industry or partner in...

  5. Utilização de frutos de cactos (Cactaceae como recurso alimentar por vespas sociais (Hymenoptera, Vespidae, Polistinae em uma área de caatinga (Ipirá, Bahia, Brasil The use of cactus fruit food resources by social wasp (Hymenoptera, Vespidae, Polistinae in an area of Caatinga (lpirá, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Gilberto M. M. Santos

    2007-12-01

    Full Text Available Este estudo teve por objetivo identificar as espécies utilizadas como recurso alimentar e descrever os padrões locais de utilização de frutos de cactos como recurso alimentar por vespas sociais em uma área de Caatinga. Novecentos e oito indivíduos de nove espécies de vespas foram capturados visitando seis espécies de cactáceas. Cereus jamacaru DC. e Pilosocereus catingicola (Gurke Byles & G.D foram as cactáceas mais utilizadas por vespas sociais, tanto em número de espécies quanto de indivíduos. Polybia paulista von Ihering, 1896, Polybia ignobilis (Haliday, 1836, Polistes versicolor (Olivier, 1791, Polistes simillimus Zikán, 1951, Polistes billardieri Fabricius, 1804, Polistes canadensis (Linnaeus, 1758, Polybia occidentalis (Olivier, 1791 e Polybia sericea (Olivier, 1705 apresentaram as maiores amplitudes de nicho trófico. As maiores sobreposições no nicho trófico foram observadas entre Mischocyttarus lanei Zikán, 1949 e Polistes simillimus Zikán, 1951 (0,83. Os altos níveis de sobreposição de nichos observados são explicados em função do comportamento generalista das vespas sociais, bem como da exploração intensiva de poucas espécies de cactáceas.This study aims to identify food resource plants used by social wasp species in a Caatinga area, as well as describe the local patterns of cactus fruit resources used by wasps. Nine hundreds and eight foraging wasps, belonging to nine species, were captured while visiting six cactus species. Cereus jamacaru DC. and Pilosocereus catingicola (Gurke Byles & G.D. were the most frequently visited plants. Several wasp species and a great number of individuals visited them. Polybia paulista von Ihering, 1896, Polybia ignobilis (Haliday, 1836, Polistes versicolor (Olivier, 1791, Polistes simillimus Zikán, 1951, Polistes billardieri Fabricius, 1804, Polistes canadensis (Linnaeus, 1758, Polybia occidentalis (Olivier, 1791 and Polybia sericea (Olivier, 1705 had the larger trophic

  6. Elementos traqueais de cinco táxons de Cactaceae da caatinga pernambucana, Brasil Traqueary elements of five taxons of Cactaceae of the caatinga from Pernambuco State, Brazil

    Directory of Open Access Journals (Sweden)

    Emília Cristina Pereira de Arruda

    2004-12-01

    Full Text Available Este trabalho traz a caracterização morfológica de elementos de vaso e WBT ("traqueíde com espessamento largo" de raiz e cladódio de cinco táxons de Cactaceae (Harrisia adscendens (Gurke Britton & Rose, Melocactus × horridus Wedermann Notizbl., M. zehntneri (Britton & Rose Luetzelb., Tacinga inamoena (Schumann N.P. Taylor & Stuppy e T. palmadora (Britton & Rose N.P. Taylor & Stuppy ocorrentes em um trecho de caatinga do Estado de Pernambuco, Brasil. Os elementos de vaso observados tanto nas raízes quanto nos cladódios apresentam-se praticamente idênticos entre os táxons estudados, sendo observadas pontoações alternas, opostas e escalariformes, além de placas de perfuração simples transversal e obliqua. As traqueídes (WBT foram registradas apenas nos cladódios de quatro dos táxons estudados, exceto em Harrisia adscendens. As WBTs apresentam espessamento anelar ou helicoidal e o espessamento misto ocorre apenas em Melocactus. Os elementos traqueais foram medidos, mostrando que em Melocactus tanto a raiz como o cladódio, apresentam elementos de vaso longos e quanto as WBT essas são maiores no cladódio de Melocactus.This work brings a morphological characterization of traqueary elements (vessels and tracheids in root and cladode of five taxons of Cactaceae (Harrisia adscendens (Gurke Britton & Rose, Melocactus × horridus Wedermann Notizbl., M. zehntneri (Britton & Rose Luetzelb., Tacinga inamoena (Schumann N.P. Taylor & Stuppy and T. palmadora (Britton & Rose N.P. Taylor & Stuppy occurent in the caatinga of Pernambuco State, Brazil. The vessels elements observed in the roots and cladodes seem almost same among the studied taxons, were observed alternate, opposite and scalariform pitting, and simple perforation plate transversal or oblique. The tracheids (WBT were exclusively noted in the cladodes of four studied taxons, except Harrisia adscendens. The WBTs with annular and helical thickening are present in all taxons and the

  7. How Auditory Information Influences Volitional Control in Binocular Rivalry: Modulation of a Top-Down Attentional Effect

    Directory of Open Access Journals (Sweden)

    Manuel Vidal

    2011-10-01

    Full Text Available Although multistable perception has long been studied, in recent years, paradigms involving ambiguous visual stimuli have been used to assess phenomenal awareness. Indeed, for such stimuli, although the sensory input is invariant, a perceptual decision occurs bringing to awareness only one of the possible interpretations. Moreover, the observer experiences inevitable oscillations between these percepts. Only few studies have tackled bistability for multimodal percepts. Conrad et al. [1] presented dot fields going in opposite direction to each eye, they found that lateral sound motion prolongs the dominance duration of the coherent visual motion percept and not the other. In this study, the volitional control—the capacity to promote a given percept—was not assessed. Van Ee et al. [2] tested how sensory congruency influences volitional control using looming motion stimuli that could be seen, heard or sensed on the hand. They found that attention to the additional modality (sound or touch has to be engaged to promote visual dominance and that only temporal congruency is required in the end. In both studies such low-level stimuli could have reduced the possibility of finding passive interactions and limited the congruency to temporal features, which motivated the use of higher-level audio-visual speech processing in our experiments. Accordingly, we used the McGurk effect [4] involving robust audio-visual integration to investigate multimodal rivalry. After measuring the perceptual oscillation dynamics of rivaling videos (lips pronouncing /aba/ vs. /aga/, we added the sound /aba/ in order to assess the influence of audio-visual integration on the perceptual dynamics. Adding the sound /aba/ increased the dominance durations of both percepts when viewed passively. For McGurk sensitive participants, it also increased the capacity to promote lips uttering /aba/ percept as compared to the same situation without sound; but not for lips uttering /aga

  8. Visual speech acts differently than lexical context in supporting speech perception.

    Science.gov (United States)

    Samuel, Arthur G; Lieblich, Jerrold

    2014-08-01

    The speech signal is often badly articulated, and heard under difficult listening conditions. To deal with these problems, listeners make use of various types of context. In the current study, we examine a type of context that in previous work has been shown to affect how listeners report what they hear: visual speech (i.e., the visible movements of the speaker's articulators). Despite the clear utility of this type of context under certain conditions, prior studies have shown that visually driven phonetic percepts (via the "McGurk" effect) are not "real" enough to affect perception of later-occurring speech; such percepts have not produced selective adaptation effects. This failure contrasts with successful adaptation by sounds that are generated by lexical context-the word that a sound occurs within. We demonstrate here that this dissociation is robust, leading to the conclusion that visual and lexical contexts operate differently. We suggest that the dissociation reflects the dual nature of speech as both a perceptual object and a linguistic object. Visual speech seems to contribute directly to the computations of the perceptual object but not the linguistic one, while lexical context is used in both types of computations.

  9. No need to talk, I know you: familiarity influences early multisensory integration in a songbird's brain

    Directory of Open Access Journals (Sweden)

    Isabelle GEORGE

    2011-01-01

    Full Text Available It is well known that visual information can affect auditory perception, as in the famous McGurk effect, but little is known concerning the processes involved. To address this issue, we used the best-developed animal model to study language-related processes in the brain: songbirds. European starlings were exposed to audiovisual compared to auditory-only playback of conspecific songs, while electrophysiological recordings were made in their primary auditory area (Field L. The results show that the audiovisual condition modulated the auditory responses. Enhancement and suppression were both observed, depending on the stimulus familiarity. Seeing a familiar bird led to suppressed auditory responses while seeing an unfamiliar bird led to response enhancement, suggesting that unisensory perception may be enough if the stimulus is familiar while redundancy may be required for unfamiliar items. This is to our knowledge the first evidence that multisensory integration may occur in a low-level, putatively unisensory area of a non-mammalian vertebrate brain, and also that familiarity of the stimuli may influence modulation of auditory responses by vision.

  10. Visual recalibration and selective adaptation in auditory-visual speech perception: Contrasting build-up courses.

    Science.gov (United States)

    Vroomen, Jean; van Linden, Sabine; de Gelder, Béatrice; Bertelson, Paul

    2007-02-01

    Exposure to incongruent auditory and visual speech produces both visual recalibration and selective adaptation of auditory speech identification. In an earlier study, exposure to an ambiguous auditory utterance (intermediate between /aba/ and /ada/) dubbed onto the video of a face articulating either /aba/ or /ada/, recalibrated the perceived identity of auditory targets in the direction of the visual component, while exposure to congruent non-ambiguous /aba/ or /ada/ pairs created selective adaptation, i.e. a shift of perceived identity in the opposite direction [Bertelson, P., Vroomen, J., & de Gelder, B. (2003). Visual recalibration of auditory speech identification: a McGurk aftereffect. Psychological Science, 14, 592-597]. Here, we examined the build-up course of the after-effects produced by the same two types of bimodal adapters, over a 1-256 range of presentations. The (negative) after-effects of non-ambiguous congruent adapters increased monotonically across that range, while those of ambiguous incongruent adapters followed a curvilinear course, going up and then down with increasing exposure. This pattern is discussed in terms of an asynchronous interaction between recalibration and selective adaptation processes.

  11. The influence of selective attention to auditory and visual speech on the integration of audiovisual speech information.

    Science.gov (United States)

    Buchan, Julie N; Munhall, Kevin G

    2011-01-01

    Conflicting visual speech information can influence the perception of acoustic speech, causing an illusory percept of a sound not present in the actual acoustic speech (the McGurk effect). We examined whether participants can voluntarily selectively attend to either the auditory or visual modality by instructing participants to pay attention to the information in one modality and to ignore competing information from the other modality. We also examined how performance under these instructions was affected by weakening the influence of the visual information by manipulating the temporal offset between the audio and video channels (experiment 1), and the spatial frequency information present in the video (experiment 2). Gaze behaviour was also monitored to examine whether attentional instructions influenced the gathering of visual information. While task instructions did have an influence on the observed integration of auditory and visual speech information, participants were unable to completely ignore conflicting information, particularly information from the visual stream. Manipulating temporal offset had a more pronounced interaction with task instructions than manipulating the amount of visual information. Participants' gaze behaviour suggests that the attended modality influences the gathering of visual information in audiovisual speech perception.

  12. Vision of tongue movements bias auditory speech perception.

    Science.gov (United States)

    D'Ausilio, Alessandro; Bartoli, Eleonora; Maffongelli, Laura; Berry, Jeffrey James; Fadiga, Luciano

    2014-10-01

    Audiovisual speech perception is likely based on the association between auditory and visual information into stable audiovisual maps. Conflicting audiovisual inputs generate perceptual illusions such as the McGurk effect. Audiovisual mismatch effects could be either driven by the detection of violations in the standard audiovisual statistics or via the sensorimotor reconstruction of the distal articulatory event that generated the audiovisual ambiguity. In order to disambiguate between the two hypotheses we exploit the fact that the tongue is hidden to vision. For this reason, tongue movement encoding can solely be learned via speech production but not via others׳ speech perception alone. Here we asked participants to identify speech sounds while matching or mismatching visual representations of tongue movements which were shown. Vision of congruent tongue movements facilitated auditory speech identification with respect to incongruent trials. This result suggests that direct visual experience of an articulator movement is not necessary for the generation of audiovisual mismatch effects. Furthermore, we suggest that audiovisual integration in speech may benefit from speech production learning. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Speech and non-speech audio-visual illusions: a developmental study.

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    Corinne Tremblay

    Full Text Available It is well known that simultaneous presentation of incongruent audio and visual stimuli can lead to illusory percepts. Recent data suggest that distinct processes underlie non-specific intersensory speech as opposed to non-speech perception. However, the development of both speech and non-speech intersensory perception across childhood and adolescence remains poorly defined. Thirty-eight observers aged 5 to 19 were tested on the McGurk effect (an audio-visual illusion involving speech, the Illusory Flash effect and the Fusion effect (two audio-visual illusions not involving speech to investigate the development of audio-visual interactions and contrast speech vs. non-speech developmental patterns. Whereas the strength of audio-visual speech illusions varied as a direct function of maturational level, performance on non-speech illusory tasks appeared to be homogeneous across all ages. These data support the existence of independent maturational processes underlying speech and non-speech audio-visual illusory effects.

  14. Visual-tactile integration in speech perception: Evidence for modality neutral speech primitives.

    Science.gov (United States)

    Bicevskis, Katie; Derrick, Donald; Gick, Bryan

    2016-11-01

    Audio-visual [McGurk and MacDonald (1976). Nature 264, 746-748] and audio-tactile [Gick and Derrick (2009). Nature 462(7272), 502-504] speech stimuli enhance speech perception over audio stimuli alone. In addition, multimodal speech stimuli form an asymmetric window of integration that is consistent with the relative speeds of the various signals [Munhall, Gribble, Sacco, and Ward (1996). Percept. Psychophys. 58(3), 351-362; Gick, Ikegami, and Derrick (2010). J. Acoust. Soc. Am. 128(5), EL342-EL346]. In this experiment, participants were presented video of faces producing /pa/ and /ba/ syllables, both alone and with air puffs occurring synchronously and at different timings up to 300 ms before and after the stop release. Perceivers were asked to identify the syllable they perceived, and were more likely to respond that they perceived /pa/ when air puffs were present, with asymmetrical preference for puffs following the video signal-consistent with the relative speeds of visual and air puff signals. The results demonstrate that visual-tactile integration of speech perception occurs much as it does with audio-visual and audio-tactile stimuli. This finding contributes to the understanding of multimodal speech perception, lending support to the idea that speech is not perceived as an audio signal that is supplemented by information from other modes, but rather that primitives of speech perception are, in principle, modality neutral.

  15. Frame rate of motion picture and its influence on speech perception

    Science.gov (United States)

    Nakazono, Kaoru

    1996-03-01

    The preservation of QoS for multimedia traffic through a data network is a difficult problem. We focus our attention on video frame rate and study its influence on speech perception. When sound and picture are discrepant (e.g., acoustic `ba' combined with visual `ga'), subjects perceive a different sound (such as `da'). This phenomenon is known as the McGurk effect. In this paper, the influence of degraded video frame rate on speech perception was studied. It was shown that when frame rate decreases, correct hearing is improved for discrepant stimuli and is degraded for congruent (voice and picture are the same) stimuli. Furthermore, we studied the case where lip closure was always captured by the synchronization of sampling time and lip position. In this case, frame rate has little effect on mishearing for congruent stimuli. For discrepant stimuli, mishearing is decreased with degraded frame rate. These results indicate that stiff motion of lips resulting from low frame rate cannot give enough labial information for speech perception. In addition, the effect of delaying the picture to correct for low frame rate was studied. The results, however, were not as definitive as expected because of compound effects related to the synchronization of sound and picture.

  16. Audiovisual bimodal mutual compensation of Chinese

    Institute of Scientific and Technical Information of China (English)

    ZHOU; Zhi

    2001-01-01

    [1]Richard, P., Schumeyer, Kenneth E. B., The effect of visual information on word initial consonant perception of dysarthric speech, in Proc. ICSLP'96 October 3-6 1996, Philadephia, Pennsylvania, USA.[2]Goff, B. L., Marigny, T. G., Benoit, C., Read my lips...and my jaw! How intelligible are the components of a speaker's face? Eurospeech'95, 4th European Conference on Speech Communication and Technology, Madrid, September 1995.[3]McGurk, H., MacDonald, J. Hearing lips and seeing voices, Nature, 1976, 264: 746.[4]Duran A. F., Mcgurk effect in Spanish and German listeners: Influences of visual cues in the perception of Spanish and German confliction audio-visual stimuli, Eurospeech'95. 4th European Conference on Speech Communication and Technology, Madrid, September 1995.[5]Luettin, J., Visual speech and speaker recognition, Ph.D thesis, University of Sheffield, 1997.[6]Xu Yanjun, Du Limin, Chinese audiovisual bimodal speech database CAVSR1.0, Chinese Journal of Acoustics, to appear.[7]Zhang Jialu, Speech corpora and language input/output methods' evaluation, Chinese Applied Acoustics, 1994, 13(3): 5.

  17. Absence of cue-recruitment for extrinsic signals: sounds, spots, and swirling dots fail to influence perceived 3D rotation direction after training.

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    Anshul Jain

    Full Text Available The visual system can learn to use information in new ways to construct appearance. Thus, signals such as the location or translation direction of an ambiguously rotating wire frame cube, which are normally uninformative, can be learned as cues to determine the rotation direction. This perceptual learning occurs when the formerly uninformative signal is statistically associated with long-trusted visual cues (such as binocular disparity that disambiguate appearance during training. In previous demonstrations, the newly learned cue was intrinsic to the perceived object, in that the signal was conveyed by the same image elements as the object itself. Here we used extrinsic new signals and observed no learning. We correlated three new signals with long-trusted cues in the rotating cube paradigm: one crossmodal (an auditory signal and two within modality (visual. Cue recruitment did not occur in any of these conditions, either in single sessions or in ten sessions across as many days. These results suggest that the intrinsic/extrinsic distinction is important for the perceptual system in determining whether it can learn and use new information from the environment to construct appearance. Extrinsic cues do have perceptual effects (e.g. the "bounce-pass" illusion and McGurk effect, so we speculate that extrinsic signals must be recruited for perception, but only if certain conditions are met. These conditions might specify the age of the observer, the strength of the long-trusted cues, or the amount of exposure to the correlation.

  18. Sight and sound persistently out of synch: stable individual differences in audiovisual synchronisation revealed by implicit measures of lip-voice integration.

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    Ipser, Alberta; Agolli, Vlera; Bajraktari, Anisa; Al-Alawi, Fatimah; Djaafara, Nurfitriani; Freeman, Elliot D

    2017-04-21

    Are sight and sound out of synch? Signs that they are have been dismissed for over two centuries as an artefact of attentional and response bias, to which traditional subjective methods are prone. To avoid such biases, we measured performance on objective tasks that depend implicitly on achieving good lip-synch. We measured the McGurk effect (in which incongruent lip-voice pairs evoke illusory phonemes), and also identification of degraded speech, while manipulating audiovisual asynchrony. Peak performance was found at an average auditory lag of ~100 ms, but this varied widely between individuals. Participants' individual optimal asynchronies showed trait-like stability when the same task was re-tested one week later, but measures based on different tasks did not correlate. This discounts the possible influence of common biasing factors, suggesting instead that our different tasks probe different brain networks, each subject to their own intrinsic auditory and visual processing latencies. Our findings call for renewed interest in the biological causes and cognitive consequences of individual sensory asynchronies, leading potentially to fresh insights into the neural representation of sensory timing. A concrete implication is that speech comprehension might be enhanced, by first measuring each individual's optimal asynchrony and then applying a compensatory auditory delay.

  19. Susceptibility to a multisensory speech illusion in older persons is driven by perceptual processes

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    Annalisa eSetti

    2013-09-01

    Full Text Available Recent studies suggest that multisensory integration is enhanced in older adults but it is not known whether this enhancement is solely driven by perceptual processes or affected by cognitive processes. Using the ‘McGurk illusion’, in Experiment 1 we found that audio-visual integration of incongruent audio-visual words was higher in older adults than in younger adults, although the recognition of either audio- or visual-only presented words was the same across groups. In Experiment 2 we tested recall of sentences within which an incongruent audio-visual speech word was embedded. The overall semantic meaning of the sentence was compatible with either one of the unisensory components of the target word and/or with the illusory percept. Older participants recalled more illusory audio-visual words in sentences than younger adults, however, there was no differential effect of word compatibility on recall for the two groups. Our findings suggest that the relatively high susceptibility to the audio-visual speech illusion in older participants is due more to perceptual than cognitive processing.

  20. Read My Lips: Brain Dynamics Associated with Audiovisual Integration and Deviance Detection.

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    Tse, Chun-Yu; Gratton, Gabriele; Garnsey, Susan M; Novak, Michael A; Fabiani, Monica

    2015-09-01

    Information from different modalities is initially processed in different brain areas, yet real-world perception often requires the integration of multisensory signals into a single percept. An example is the McGurk effect, in which people viewing a speaker whose lip movements do not match the utterance perceive the spoken sounds incorrectly, hearing them as more similar to those signaled by the visual rather than the auditory input. This indicates that audiovisual integration is important for generating the phoneme percept. Here we asked when and where the audiovisual integration process occurs, providing spatial and temporal boundaries for the processes generating phoneme perception. Specifically, we wanted to separate audiovisual integration from other processes, such as simple deviance detection. Building on previous work employing ERPs, we used an oddball paradigm in which task-irrelevant audiovisually deviant stimuli were embedded in strings of non-deviant stimuli. We also recorded the event-related optical signal, an imaging method combining spatial and temporal resolution, to investigate the time course and neuroanatomical substrate of audiovisual integration. We found that audiovisual deviants elicit a short duration response in the middle/superior temporal gyrus, whereas audiovisual integration elicits a more extended response involving also inferior frontal and occipital regions. Interactions between audiovisual integration and deviance detection processes were observed in the posterior/superior temporal gyrus. These data suggest that dynamic interactions between inferior frontal cortex and sensory regions play a significant role in multimodal integration.

  1. Cross-Modal Perception in the Framework of Non-Riemannian Sensory Space

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    Masaru Shimbo

    2011-10-01

    Full Text Available Though human sensations, such as the senses of hearing, sight, etc., are independent each other, the interference between two of them is sometimes observed, and is called cross-modal perception[1]. Hitherto we studied unimodal perception of visual sensation[2] and auditory sensation[3] respectively by differential geometry[4]. We interpreted the parallel alley and the distance alley as two geodesics under different conditions in a visual space, and depicted the trace of continuous vowel speech as the geodesics through phonemes on a vowel plane. In this work, cross-modal perception is similarly treated from the standpoint of non-Riemannian geometry, where each axis of a cross-modal sensory space represents unimodal sensation. The geometry allows us to treat asymmetric metric tensor and hence a non-Euclidean concept of anholonomic objects, representing unidirectional property of cross-modal perception. The McGurk effect in audiovisual perception[5] and ‘rubber hand’ illusion in visual tactile perception[6] can afford experimental evidence of torsion tensor. The origin of ‘bouncing balls’ illusion[7] is discussed from the standpoint of an audiovisual cross-modal sensory space in a qualitative manner.

  2. Long-term impact after fulminant Guillain-Barré syndrome, case report and literature review

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    Rougé A

    2016-11-01

    Full Text Available Alain Rougé,1,2 Jérémie Lemarié,1,2 Sébastien Gibot,1,2 Pierre Edouard Bollaert1,2 1Medical Intensive Care Unit, Hôpital Central, University Hospital of Nancy, Nancy, France; 2INSERM UMRS-1116, Faculty of Medicine, University of Lorraine, Nancy, France Abstract: A 47-year-old man was admitted to the intensive care unit a few hours after ­presenting to emergency department with acute diplopia and dysphonia. Swallowing disorders and respiratory muscular weakness quickly required invasive ventilation. On day 3, the patient was in a “brain-death”-like state with deep coma and absent brainstem reflexes. Electroencephalogram ruled out brain death diagnosis as a paradoxical sleep trace was recorded. Cerebrospinal fluid analysis, electrophysiologic studies, and a recent history of diarrhea led to the diagnosis of Campylobacter jejuni-related fulminant Guillain-Barré syndrome (GBS mimicking brain death. The outcome was favorable after long Intensive Care Unit and inpatient rehabilitation stays, despite persistent disability at 9 years follow-up. This case and the associated literature review of 34 previously reported fulminant GBS patients emphasize the importance of electrophysiological investigations during clinical brain-death states with no definite cause. Fulminant GBS has a worse outcome than “standard” GBS with higher rates of severe disability (about 50%. Long-term physiotherapy and specific rehabilitation programs appear essential to improve recovery. Keywords: fulminant Guillain-Barré syndrome, brain death, electroencephalogram, C. jejuni, long-term follow 

  3. A universal bias in adult vowel perception - By ear or by eye.

    Science.gov (United States)

    Masapollo, Matthew; Polka, Linda; Ménard, Lucie

    2017-09-01

    Speech perceivers are universally biased toward "focal" vowels (i.e., vowels whose adjacent formants are close in frequency, which concentrates acoustic energy into a narrower spectral region). This bias is demonstrated in phonetic discrimination tasks as a directional asymmetry: a change from a relatively less to a relatively more focal vowel results in significantly better performance than a change in the reverse direction. We investigated whether the critical information for this directional effect is limited to the auditory modality, or whether visible articulatory information provided by the speaker's face also plays a role. Unimodal auditory and visual as well as bimodal (auditory-visual) vowel stimuli were created from video recordings of a speaker producing variants of /u/, differing in both their degree of focalization and visible lip rounding (i.e., lip compression and protrusion). In Experiment 1, we confirmed that subjects showed an asymmetry while discriminating the auditory vowel stimuli. We then found, in Experiment 2, a similar asymmetry when subjects lip-read those same vowels. In Experiment 3, we found asymmetries, comparable to those found for unimodal vowels, for bimodal vowels when the audio and visual channels were phonetically-congruent. In contrast, when the audio and visual channels were phonetically-incongruent (as in the "McGurk effect"), this asymmetry was disrupted. These findings collectively suggest that the perceptual processes underlying the "focal" vowel bias are sensitive to articulatory information available across sensory modalities, and raise foundational issues concerning the extent to which vowel perception derives from general-auditory or speech-gesture-specific processes. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Chronotropic incompetence can limit exercise tolerance in COPD patients with lung hyperinflation

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    Hulo S

    2016-10-01

    Full Text Available Sébastien Hulo,1 Jocelyn Inamo,2 Aurélie Dehon,3 Olivier Le Rouzic,4 Jean-Louis Edme,1 Remi Neviere51Université Lille, CHU Lille, EA 4483, IMPact de l’Environnement Chimique sur la Santé humaine, Lille, France; 2Département de Cardiologie – CHU Fort de France, Martinique – Faculté de Médecine – Université des Antilles, France; 3Pôle d’Anesthésie Réanimation ADRU, CHU Nîmes, Nîmes, France; 4Université Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France; 5Université Lille, Inserm, CHU Lille, Lille Inflammation Research International Center, Lille, FrancePurpose: Metabolic-chronotropic relationship is the only concept that assesses the entire chronotropic function during exercise, as it takes into account individual fitness. To better understand interrelationships between chronotropic incompetence (CI, dynamic hyperinflation (DH and exercise limitation among Global initiative for chronic Obstructive Lung Disease (GOLD stages of chronic obstructive pulmonary disease (COPD disease severity, we evaluated cardiopulmonary responses to symptom-limited cycle exercise in stable patients.Patients and methods: We prospectively studied 47 COPD patients classified by GOLD stage severity. Pulmonary function tests and cardiopulmonary responses to symptom-limited incremental exercise were studied. CI was defined by regression line between percent heart rate (HR reserve and percent oxygen uptake (V’O2 reserve, ie, chronotropic-metabolic index (CMI. DH was defined from the knot resulting from the nonlinear regressions of inspiratory capacity changes from rest to peak (dynamic inspiratory capacity (ICdyn with percentage of maximal HR and CMI.Results: Aerobic capacity (median interquartile ranges peak V’O2, 24.3 (23.6; 25.2, 18.5 (15.5; 21.8, 17.5 (15.4; 19.1 mL·kg-1·min-1 and CMI worsened according to GOLD severity. The optimal knot of ICdyn was equal to −0.34 L. The

  5. Age-related hearing loss in individuals and their caregivers: effects of coping on the quality of life among the dyads

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    Lazzarotto S

    2016-11-01

    Full Text Available Sébastien Lazzarotto,1,2 Karine Baumstarck,1 Anderson Loundou,1 Zeinab Hamidou,1,3 Valérie Aghababian,1 Tanguy Leroy,1,4 Pascal Auquier1 1EA 3279, Self-Perceived Health Assessment Research Unit, School of Medicine, Aix Marseille Université, 2French Regional Institute for Prevention of Aging, Marseille, 3National Clinical Research Quality of Life in Oncology Platform, Marseille, 4Social Psychology Research Group (GRePS EA 4163, Université Lumière Lyon 2, Bron, France Objectives: Age-related hearing loss (ARHL impacts the daily living and quality of life (QoL of affected individuals and the functioning of family caregivers. In the specific context of voluntary medical checkups, we examined sample dyads (ARHL individual and the caregiver to determine whether QoL of patients and caregivers is influenced by coping strategies implemented either by themselves or their relatives.Methods: This was a cross-sectional study with a descriptive/correlative design performed in a French preventive health center (Regional Institute for Prevention of Aging, Marseille, France for the beneficiaries of pension funds of private sector employees. The samples included beneficiary–caregiver dyads. The beneficiaries had bilateral (mild to moderately severe ARHL. Self-reported data were collected as follows: QoL using the World Health Organization Quality of Life questionnaire, coping strategies using the Brief Coping Orientation to Problems Experienced Scale, and anxiety and mood using visual analog scales.Results: The final sample comprised 44 beneficiaries and 44 caregivers. The caregiver was the partner of the beneficiary in 73% of cases. The QoL scores of the social dimension were significantly lower for beneficiaries and caregivers compared with French age- and sex-matched controls. Among beneficiaries and caregivers, coping strategies based on problem solving were the most commonly used strategies. The use of positive thinking strategies was associated with

  6. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

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    Valour F

    2014-07-01

    Full Text Available Florent Valour,1–3 Agathe Sénéchal,1,2 Céline Dupieux,2–4 Judith Karsenty,1,2 Sébastien Lustig,2,5 Pierre Breton,2,6 Arnaud Gleizal,2,7 Loïc Boussel,2,8,9 Frédéric Laurent,2–4 Evelyne Braun,1 Christian Chidiac,1–3 Florence Ader,1–3 Tristan Ferry1–3 1Service des Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 2Université Claude Bernard Lyon 1, Lyon, France; 3Centre International de Recherche en Infectiologie, CIRI, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France; 4Laboratoire de Bactériologie, Centre de Biologie du Nord, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 5Chirurgie Orthopédique, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 6Stomatologie et Chirurgie Maxillo-faciale, Hospices Civils de Lyon, Groupement Hospitalier Sud, Lyon, France; 7Chirurgie Maxillo-faciale, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 8Radiologie, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 9Creatis, CNRS UMR 5220, INSERM U1044, Université Lyon 1, INSA Lyon, Lyon, France Abstract: Actinomycosis is a rare chronic disease caused by Actinomyces spp., anaerobic Gram-positive bacteria that normally colonize the human mouth and digestive and genital tracts. Physicians must be aware of typical clinical presentations (such as cervicofacial actinomycosis following dental focus of infection, pelvic actinomycosis in women with an intrauterine device, and pulmonary actinomycosis in smokers with poor dental hygiene, but also that actinomycosis may mimic the malignancy process in various anatomical sites. Bacterial cultures and pathology are the cornerstone of diagnosis, but particular conditions are required in order to get the correct diagnosis. Prolonged bacterial cultures in anaerobic conditions are necessary to identify the bacterium and typical microscopic findings include necrosis with

  7. Detection of label-free cancer biomarkers using nickel nanoislands and quartz crystal microbalance

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    Adrián Martínez-Rivas

    2010-09-01

    Full Text Available Adrián Martínez-Rivas1,2, Patrick Chinestra3,4, Gilles Favre3,4, Sébastien Pinaud1, Childérick Séverac1,2, Jean-Charles Faye3,4, Christophe Vieu1,21LAAS-CNRS; Université de Toulouse, Toulouse, France; 2Université de Toulouse, UPS, INSA, INP, ISAE; LAAS; Toulouse, France; 3INSERM U563, Université de Toulouse, CPTP, “Signalisation Cellulaire, GTPase Rho et cancers”, Toulouse, France; 4Institut Claudius Regaud, Biology Department, Toulouse, FranceAbstract: We present a technique for the label-free detection and recognition of cancer biomarkers using metal nanoislands intended to be integrated in a novel type of nanobiosensor. His-tagged (scFv-F7N1N2 is the antibody fragment which is directly immobilized, by coordinative bonds, onto ~5 nm nickel islands, then deposited on the surface of a quartz crystal of a quartz crystal microbalance (QCM to validate the technique. Biomarker GTPase RhoA was investigated because it has been found to be overexpressed in various tumors and because we have recently isolated and characterized a new conformational scFv which selectively recognizes the active form of RhoA. We implemented a surface chemistry involving an antibiofouling coating of polyethylene glycol silane (PEG-silane (<2 nm thick and Ni nanoislands to reach a label-free detection of the active antigen conformation of RhoA, at various concentrations. The methodology proposed here proves the viability of the concept by using Ni nanoislands as an anchoring surface layer enabling the detection of a specific conformation of a protein, identified as a potential cancer biomarker. Hence, this novel methodology can be transferred to a nanobiosensor to detect, at lower time consumption and with high sensitivity, specific biomolecules.Keywords: nickel nanoislands, cancer biomarkers, quartz crystal microbalance, PEG-silane, RhoA protein, nanobiosensor

  8. Disposition and metabolism of [14C]-levomilnacipran, a serotonin and norepinephrine reuptake inhibitor, in humans, monkeys, and rats

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    Brunner V

    2015-06-01

    Full Text Available Valérie Brunner,1 Bernadette Maynadier,2 Laishun Chen,3 Louise Roques,2 Isabelle Hude,2 Sébastien Séguier,2 Laurence Barthe,1 Philippe Hermann11Pierre Fabre Médicament, Centre de R&D, Toulouse, 2Centre Experimental PreClinque, Campans, France; 3Forest Research Institute Inc., an affiliate of Actavis Inc., Jersey City, NJ, USAAbstract: Levomilnacipran is approved in the US for the treatment of major depressive disorder in adults. We characterized the metabolic profile of levomilnacipran in humans, monkeys, and rats after oral administration of [14C]-levomilnacipran. In vitro binding of levomilnacipran to human plasma proteins was also studied. Unchanged levomilnacipran was the major circulating compound after dosing in all species. Within 12 hours of dosing in humans, levomilnacipran accounted for 52.9% of total plasma radioactivity; the circulating metabolites N-desethyl levomilnacipran N-carbamoyl glucuronide, N-desethyl levomilnacipran, and levomilnacipran N-carbamoyl glucuronide accounted for 11.3%, 7.5%, and 5.6%, respectively. Similar results were seen in monkeys. N-Desethyl levomilnacipran and p-hydroxy levomilnacipran were the main circulating metabolites in rats. Mass balance results indicated that renal excretion was the major route of elimination with 58.4%, 35.5%, and 40.2% of total radioactivity being excreted as unchanged levomilnacipran in humans, monkeys, and rats, respectively. N-Desethyl levomilnacipran was detected in human, monkey, and rat urine (18.2%, 12.4%, and 7.9% of administered dose, respectively. Human and monkey urine contained measurable quantities of levomilnacipran glucuronide (3.8% and 4.1% of administered dose, respectively and N-desethyl levomilnacipran glucuronide (3.2% and 2.3% of administered dose, respectively; these metabolites were not detected in rat urine. The metabolites p-hydroxy levomilnacipran and p-hydroxy levomilnacipran glucuronide were detected in human urine (≤1.2% of administered dose

  9. Transfert radiatif numerique pour un code SPH

    Science.gov (United States)

    Viau, Joseph Edmour Serge

    2001-03-01

    & Bastien (1993) qui tentait d'expliquer le phenomene FU Orionis. Bien que ces deux situations ne furent pas totalement approfondies dans notre cas, nous reussissons tout de meme a obtenir des resultats interessants. Tout ceci nous ouvre la porte a de nombreuses possibilites de projets qui pourront certainement etre effectues dans les annees a venir.

  10. Large Scale Functional Brain Networks Underlying Temporal Integration of Audio-Visual Speech Perception: An EEG Study

    Science.gov (United States)

    Kumar, G. Vinodh; Halder, Tamesh; Jaiswal, Amit K.; Mukherjee, Abhishek; Roy, Dipanjan; Banerjee, Arpan

    2016-01-01

    Observable lip movements of the speaker influence perception of auditory speech. A classical example of this influence is reported by listeners who perceive an illusory (cross-modal) speech sound (McGurk-effect) when presented with incongruent audio-visual (AV) speech stimuli. Recent neuroimaging studies of AV speech perception accentuate the role of frontal, parietal, and the integrative brain sites in the vicinity of the superior temporal sulcus (STS) for multisensory speech perception. However, if and how does the network across the whole brain participates during multisensory perception processing remains an open question. We posit that a large-scale functional connectivity among the neural population situated in distributed brain sites may provide valuable insights involved in processing and fusing of AV speech. Varying the psychophysical parameters in tandem with electroencephalogram (EEG) recordings, we exploited the trial-by-trial perceptual variability of incongruent audio-visual (AV) speech stimuli to identify the characteristics of the large-scale cortical network that facilitates multisensory perception during synchronous and asynchronous AV speech. We evaluated the spectral landscape of EEG signals during multisensory speech perception at varying AV lags. Functional connectivity dynamics for all sensor pairs was computed using the time-frequency global coherence, the vector sum of pairwise coherence changes over time. During synchronous AV speech, we observed enhanced global gamma-band coherence and decreased alpha and beta-band coherence underlying cross-modal (illusory) perception compared to unisensory perception around a temporal window of 300–600 ms following onset of stimuli. During asynchronous speech stimuli, a global broadband coherence was observed during cross-modal perception at earlier times along with pre-stimulus decreases of lower frequency power, e.g., alpha rhythms for positive AV lags and theta rhythms for negative AV lags. Thus

  11. Large Scale Functional Brain Networks Underlying Temporal Integration of Audio-Visual Speech Perception: An EEG Study.

    Science.gov (United States)

    Kumar, G Vinodh; Halder, Tamesh; Jaiswal, Amit K; Mukherjee, Abhishek; Roy, Dipanjan; Banerjee, Arpan

    2016-01-01

    Observable lip movements of the speaker influence perception of auditory speech. A classical example of this influence is reported by listeners who perceive an illusory (cross-modal) speech sound (McGurk-effect) when presented with incongruent audio-visual (AV) speech stimuli. Recent neuroimaging studies of AV speech perception accentuate the role of frontal, parietal, and the integrative brain sites in the vicinity of the superior temporal sulcus (STS) for multisensory speech perception. However, if and how does the network across the whole brain participates during multisensory perception processing remains an open question. We posit that a large-scale functional connectivity among the neural population situated in distributed brain sites may provide valuable insights involved in processing and fusing of AV speech. Varying the psychophysical parameters in tandem with electroencephalogram (EEG) recordings, we exploited the trial-by-trial perceptual variability of incongruent audio-visual (AV) speech stimuli to identify the characteristics of the large-scale cortical network that facilitates multisensory perception during synchronous and asynchronous AV speech. We evaluated the spectral landscape of EEG signals during multisensory speech perception at varying AV lags. Functional connectivity dynamics for all sensor pairs was computed using the time-frequency global coherence, the vector sum of pairwise coherence changes over time. During synchronous AV speech, we observed enhanced global gamma-band coherence and decreased alpha and beta-band coherence underlying cross-modal (illusory) perception compared to unisensory perception around a temporal window of 300-600 ms following onset of stimuli. During asynchronous speech stimuli, a global broadband coherence was observed during cross-modal perception at earlier times along with pre-stimulus decreases of lower frequency power, e.g., alpha rhythms for positive AV lags and theta rhythms for negative AV lags. Thus, our

  12. Atypical audiovisual speech integration in infants at risk for autism.

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    Jeanne A Guiraud

    Full Text Available The language difficulties often seen in individuals with autism might stem from an inability to integrate audiovisual information, a skill important for language development. We investigated whether 9-month-old siblings of older children with autism, who are at an increased risk of developing autism, are able to integrate audiovisual speech cues. We used an eye-tracker to record where infants looked when shown a screen displaying two faces of the same model, where one face is articulating/ba/and the other/ga/, with one face congruent with the syllable sound being presented simultaneously, the other face incongruent. This method was successful in showing that infants at low risk can integrate audiovisual speech: they looked for the same amount of time at the mouths in both the fusible visual/ga/- audio/ba/and the congruent visual/ba/- audio/ba/displays, indicating that the auditory and visual streams fuse into a McGurk-type of syllabic percept in the incongruent condition. It also showed that low-risk infants could perceive a mismatch between auditory and visual cues: they looked longer at the mouth in the mismatched, non-fusible visual/ba/- audio/ga/display compared with the congruent visual/ga/- audio/ga/display, demonstrating that they perceive an uncommon, and therefore interesting, speech-like percept when looking at the incongruent mouth (repeated ANOVA: displays x fusion/mismatch conditions interaction: F(1,16 = 17.153, p = 0.001. The looking behaviour of high-risk infants did not differ according to the type of display, suggesting difficulties in matching auditory and visual information (repeated ANOVA, displays x conditions interaction: F(1,25 = 0.09, p = 0.767, in contrast to low-risk infants (repeated ANOVA: displays x conditions x low/high-risk groups interaction: F(1,41 = 4.466, p = 0.041. In some cases this reduced ability might lead to the poor communication skills characteristic of autism.

  13. Factors associated with failure to achieve remission and with relapse after remission in patients with major depressive disorder in the PERFORM study

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    Saragoussi D

    2017-08-01

    Full Text Available Delphine Saragoussi,1 Maëlys Touya,2 Josep Maria Haro,3 Bengt Jönsson,4 Martin Knapp,5 Bastien Botrel,6 Ioana Florea,7 Henrik Loft,8 Benoît Rive9 1Real-World Evidence and Epidemiology, Lundbeck SAS, Issy-les-Moulineaux, France; 2Health Economics and Outcomes Research, Lundbeck, Deerfield, IL, US; 3Research and Teaching Unit, Parc Sanitari Sant Joan de Deu, CIBERSAM, University of Barcelona, Sant Boi de Llobregat, Barcelona, Spain; 4Department of Economics, Stockholm School of Economics, Stockholm, Sweden; 5Department of Health Policy, London School of Economics and Political Science, London, UK; 6Biostatistics, Inferential, Paris, France; 7Clinical Research Paediatrics, H. Lundbeck A/S, Valby, Denmark; 8Biometrics, H. Lundbeck A/S, Valby, Denmark; 9Global Analytics, Lundbeck SAS, Issy-les-Moulineaux, France Background: The Prospective Epidemiological Research on Functioning Outcomes Related to Major Depressive Disorder (PERFORM study has been initiated to better understand the course of a depressive episode and its impact on patient functioning. This analysis aimed to identify sociodemographic and clinical factors associated with failure to achieve remission at month 2 after initiating or switching antidepressant monotherapy and with subsequent relapse at month 6 for patients in remission at month 2. Materials and methods: This was a 2-year observational cohort study in 1,159 outpatients aged 18–65 years with major depressive disorder initiating or undergoing the first switch of antidepressant monotherapy. Factors with P<0.20 in univariate logistic regression analyses were combined in a multiple logistic regression model to which backward variable selection was applied (ie, sequential removal of the least significant variable from the model and recomputation of the model until all remaining variables have P<0.05. Results: Baseline factors significantly associated with lower odds of remission at month 2 were body-mass index ≥30 kg/m2 (OR 0

  14. Watching How Planets Form

    Science.gov (United States)

    2006-09-01

    explained if the disc contains a large amount of gas, in this case, at least as much as 10 times the mass of Jupiter. It should also contain more than 50 Earth masses in dust. The dust mass derived here is more than thousand times larger than what is observed in debris discs and Kuiper belt-like structures found around older, 'Vega-like' stars, such as Beta Pictoris, Vega, Fomalhaut and HR 4796. The dust around these stars is thought to be produced by collisions of larger bodies. The dust mass observed around HD 97048 is similar to the mass invoked for the (undetected) parent bodies in the more evolved systems. HD 97048's disc is thus most likely a precursor of debris discs observed around older stars. "From the structure of the disc, we infer that planetary embryos may be present in the inner part of the disc," said Lagage. "We are planning follow-up observations at higher angular resolution with ESO's VLT interferometer in order to probe these regions." A video, made by the CEA, is also available. More Information The scientists report their discovery in the 28 September issue of Science Express, the rapid online publication service of the journal Science: "Anatomy of a flaring proto-planetary disc around a young intermediate-mass star", by P.-O. Lagage et al. The team is composed of Pierre-Olivier Lagage, Coralie Doucet, and Eric Pantin, (CEA Saclay, France), Sébastien Charnoz (Paris 7 Denis Diderot University), Emilie Habart (Institut d'Astrophysique Spatiale, Orsay, France), Gaspard Duchêne, François Ménard, and Christophe Pinte (Laboratoire d'Astrophysique de Grenoble, France), and Jan-Willem Pel (Groningen University, The Netherlands).

  15. ESTEC/Geovusie/ILEWG planetary student design workshop: a teacher training perspective

    Science.gov (United States)

    Preusterink, Jolanda; Foing, Bernard H.; Kaskes, Pim

    An important role for education is to inform and create the right skills for people to develop their own vision, using their talents to the utmost and inspire others to learn to explore in the future. Great effort has been taken to prepare this interactive design workshop thoroughly. Three days in a row, starting with presentations of Artscience The Hague to ESA colleagues, followed by a Planetary research Symposium in Amsterdam and a student design workshop at the end complemented a rich environment with the focus on Planetary exploration. The design workshop was organised by GeoVUsie students, with ESTEC and ILEWG support for tutors and inviting regional and international students to participate in an interactive workshop to design 5 Planetary Missions, with experts sharing their expertise and knowhow on specific challenging items: 1. Mercury - Post BepiColombo (with Sébastien Besse, ESA) 2. Moon South Pole Mission (with Bernard Foing, ESA) 3. Post-ExoMars - In search for Life on Mars (with Jorge Vago, ESA) 4. Humans in Space - Mars One investigated(with Arno Wielders, Space Horizon) 5. Europa - life on the icy moon of Jupiter? (with Bert Vermeersen, TU Delft) Lectures were given for more than 150 geology students at the symposium “Moon, Mars and More” at VU university, Amsterdam (organized by GeoVUsie earth science students). All students were provided with information before and at start for designing their mission. After the morning session there was a visit to the exhibition at The Erasmus Facility - ESTEC to inspire them even more with real artifacts of earlier and future missions into space. After this visit they prepared their final presentations, with original results, with innovative ideas and a good start to work out further in the future. A telescope session for geology students had been organized indoor due to rain. A follow-up visit to the nearby public Copernicus observatory was planned for another clear sky occasion. The interactive character

  16. Sharpening Up Jupiter

    Science.gov (United States)

    2008-10-01

    , MAD project manager Enrico Marchetti and Sébastien Tordo from the MAD team tracked two of Jupiter's largest moons, Europa and Io - one on each side of the planet - to provide a good correction across the full disc of the planet. "It was the most challenging observation we performed with MAD, because we had to track with high accuracy two moons moving at different speeds, while simultaneously chasing Jupiter," says Marchetti. With this unique series of images, the team found a major alteration in the brightness of the equatorial haze, which lies in a 16 000-kilometre wide belt over Jupiter's equator [2]. More sunlight reflecting off upper atmospheric haze means that the amount of haze has increased, or that it has moved up to higher altitudes. "The brightest portion had shifted south by more than 6000 kilometres," explains team member Mike Wong. This conclusion came after comparison with images taken in 2005 by Wong and colleague Imke de Pater using the Hubble Space Telescope. The Hubble images, taken at infrared wavelengths very close to those used for the VLT study, show more haze in the northern half of the bright Equatorial Zone, while the 2008 VLT images show a clear shift to the south. "The change we see in the haze could be related to big changes in cloud patterns associated with last year's planet-wide upheaval, but we need to look at more data to narrow down precisely when the changes occurred," declares Wong.

  17. PREFACE: International Conference on Strongly Correlated Electron Systems 2014 (SCES2014)

    Science.gov (United States)

    2015-03-01

    accommodation, the balance between senior and junior physicists was excellent. The weather also collaborated in a sense that the conference week was cooler than usually in July, although participants without umbrellas were often seen crossing the campus at speed! The two SCES prizes sponsored by the Philosophical Magazine to bright young physicists were respectively awarded to Max A. Metlitski (Santa Barbara) for the Mott Prize, and David Leboeuf (Grenoble) for the Coles Prize. The Coqblin Prize for developing SCES physics in emerging countries was given to Andre Strydom (Johannesburg). Of course we would like to thank all the members of the organizing committee of SCES managed by Klaus Hasselbach. During the SCES Conference two of us (JF and GL) remembered that 27 years ago, the late Jean Rossat-Mignod organized the conference ICAREA (1987) before the start of the SCES series. His enthusiasm is still with us. Topics presented at SCES2014 covered the wide area of strong correlations in Condensed Matter Physics. This proceedings volume contains papers reported at the conference, which are structured in 10 sections: S01 Heavy fermions S02 Mott insulators, correlated metals and intermetallics S03 Unconventional superconductors S04 Quantum criticality S05 Exotic ordering S06 Frustrated and quantum magnets S07 Multiferroics S08 Topological aspects S09 Low-dimensional systems and heterostructures S10 Instrumentation and methods The Proceedings of SCES2014 were edited by Mike Zhitomirsky and Pierre Dalmas de Réotier with the assistance of Dai Aoki, Kamran Behnia, Sébastien Burdin, William Knafo, Georg Knebel, Marie-Aude Méasson, Vladimir Mineev, Alexandre Pourret, Virginie Simonet, and Pierre Toulemonde. We are grateful for financial support from CEA, ESRF, ILL, Grenoble Université, and from the city council of Grenoble and the Rhône-Alpes region. Jacques Flouquet and Gerry Lander (Chairmen) Georg Knebel (General Secretary), Daniel Braithwaite (Treasurer)

  18. Anaphylaxis across two Canadian pediatric centers: evaluating management disparities

    Directory of Open Access Journals (Sweden)

    Lee AYM

    2016-12-01

    Full Text Available Alison YM Lee,1 Paul Enarson,2 Ann E Clarke,3 Sébastien La Vieille,4 Harley Eisman,5,6 Edmond S Chan,7 Christopher Mill,7 Lawrence Joseph,8 Moshe Ben-Shoshan9 1Pediatric Residency Program, Department of Pediatrics, University of British Columbia, BC Children’s Hospital, 2Division of Emergency Medicine, Department of Pediatrics, University of British Columbia, Vancouver, BC, 3Division of Rheumatology, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, 4Food Directorate, Health Canada, Ottawa, ON, 5Emergency Department, 6Department of Pediatrics, Montreal Children’s Hospital, Montreal, QC, 7Division of Allergy and Immunology, Department of Pediatrics, BC Children’s Hospital, University of British Columbia, Vancouver, BC, 8Department of Epidemiology and Biostatistics, McGill University, 9Division of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children’s Hospital, Montreal, QC, Canada Background: There are no data on the percentage of visits due to anaphylaxis in the emergency department (ED, triggers, and management of anaphylaxis across different provinces in Canada. Objective: To compare the percentage of anaphylaxis cases among all ED visits, as well as the triggers and management of anaphylaxis between two Canadian pediatric EDs (PEDs. Methods: As part of the Cross-Canada Anaphylaxis Registry (C-CARE, children presenting to the British Columbia Children’s Hospital (BCCH and Montreal Children’s Hospital (MCH EDs with anaphylaxis were recruited. Characteristics, triggers, and management of anaphylaxis were documented using a standardized data entry form. Differences in demographics, triggers, and management were determined by comparing the difference of proportions and 95% confidence interval. Results: Between June 2014 and June 2016, there were 346 visits due to anaphylaxis among 93,730 PED visits at the BCCH ED and 631 anaphylaxis visits among 164,669 pediatric visits at

  19. Raw materials exploitation in Prehistory of Georgia: sourcing, processing and distribution

    Science.gov (United States)

    Tushabramishvili, Nikoloz; Oqrostsvaridze, Avthandil

    2016-04-01

    geomorphology of different regions of Georgia. References: 1. 2015. Tushabramishvili N. Ziari. Online Archaeology 8. Tbilisi, Georgia. Pp. 41-43 2. 2012. M François-Xavier Le Bourdonnec, Sébastien Nomade, Gérard Poupeau, Hervé Guillou, Nikolos Tushabramishvili, Marie-Hélène Moncel, David Pleurdeau, Tamar Agapishvili, Pierre Voinchet, Ana Mgeladze, David Lordkipanidze). Multiple origins of Bondi Cave and Ortvale Klde (NW Georgia) obsidians and human mobility in Transcaucasia during the Middle and Upper Palaeolithic. Journal of Archaeological Science xxx (2012) 1-14 3. 2011. Mercier N., Valladas H., Meignen L., Joron J. L., Tushabramishvili N., Adler D.S., Bar Yosef O. Dating the early Middle Palaeolithic Laminar Industry from Djruchula cave, Republic of Georgia. Paléorient Volume 36. Issue 36-2, pp. 163-173 4. 2010. L. Meignen&Nicholas Tushabramishvili. Djruchula Cave, on the Southern Slopes of the Great Caucasus: An Extension of the Near Eastern Middle Paleolithic Blady Phenomenon to the North. Journal of The Israel Prehistoric Society 40 (2010), 35-61 5. 2007. Tushabramishvili N.,Pleurdeau D., Moncel M.-H., Mgeladze A. Le complexe Djruchula-Koudaro au sud Caucase (Géorgie). Remarques sur les assemblages lithiques pléistocenes de Koudaro I, Tsona et Djruchula . Anthropologie • 45/1 • pp. 1-18 6. Tushabramishvili, D., 1984. Paleolit Gruzii. (Palaeolithic of Georgia). Newsletter of the Georgian State Museum 37B, 5e27

  20. L’Immaculée Conception après le concile de Bâle dans les provinces dominicaines et franciscaines de Teutonie et de Saxe : débats et iconographie

    Directory of Open Access Journals (Sweden)

    Martina Wehrli-Johns

    2012-04-01

    la polémique et où l’imprimerie permet d’atteindre un public en dehors du cloître et de l’université. Ainsi les gravures en bois de la Vierge Immaculée trouvent-elles leur place aussi bien dans la campagne des humanistes strasbourgeois autour de Sébastien Brand que dans les illustrations du récit satirique du franciscain Thomas Murner, relatant les différents épisodes de l’affaire Jetzer à Berne.This essay proposes to follow the thread of arguments around the Immaculate Conception in Germany from the end of the Council of Basel till the early 16th century. The decision of the Council of Basel in favour of this doctrine (1439 had the effect to stir up the old dispute among the mendicant orders and especially among Dominicans and Franciscans on behalf of the Immaculate Conception. The two treaties of Otto of Hachberg, former bishop of Constance, defending the Virgin Immaculate (1444/1445, are a first testimony of this conflict in Germany. Starting with the pontificate of the Franciscan pope Sixtus IV (1471-1484 the amount of disputes and literary controversies multiplied. They came to a peak in 1512, when the Dominican Wigand Wirt was on trial in Rome for his defamatory statements and forced to revoke his utterances. The fact that the Dominican Order became increasingly isolated in this matter seems also to be a consequence of the strength of Thomism among the observant friars in Italy and Germany. Although the papal bull Grave nimis (1482 had forbidden both parts of this debate to denounce each other as heretics, the German Dominicans made often use of this weapon, thus provoking an dangerous alliance of defenders of the Immaculate Conception bringing together the observant Franciscans, the Carmelites, the Carthusians, the Augustinians and Benedictines with different circles of humanists. The analysis of the treaties and contexts of this controversy throw a sharp light upon the tensions and intellectual constellations of the religious discourse

  1. Editorial: Focus on X-ray Beams with High Coherence

    Science.gov (United States)

    Robinson, Ian; Gruebel, Gerhard; Mochrie, Simon

    2010-03-01

    This editorial serves as the preface to a special issue of New Journal of Physics, which collects together solicited papers on a common subject, x-ray beams with high coherence. We summarize the issue's content, and explain why there is so much current interest both in the sources themselves and in the applications to the study of the structure of matter and its fluctuations (both spontaneous and driven). As this collection demonstrates, the field brings together accelerator physics in the design of new sources, particle physics in the design of detectors, and chemical and materials scientists who make use of the coherent beams produced. Focus on X-ray Beams with High Coherence Contents Femtosecond pulse x-ray imaging with a large field of view B Pfau, C M Günther, S Schaffert, R Mitzner, B Siemer, S Roling, H Zacharias, O Kutz, I Rudolph, R Treusch and S Eisebitt The FERMI@Elettra free-electron-laser source for coherent x-ray physics: photon properties, beam transport system and applications E Allaria, C Callegari, D Cocco, W M Fawley, M Kiskinova, C Masciovecchio and F Parmigiani Beyond simple exponential correlation functions and equilibrium dynamics in x-ray photon correlation spectroscopy Anders Madsen, Robert L Leheny, Hongyu Guo, Michael Sprung and Orsolya Czakkel The Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS) Sébastien Boutet and Garth J Williams Dynamics and rheology under continuous shear flow studied by x-ray photon correlation spectroscopy Andrei Fluerasu, Pawel Kwasniewski, Chiara Caronna, Fanny Destremaut, Jean-Baptiste Salmon and Anders Madsen Exploration of crystal strains using coherent x-ray diffraction Wonsuk Cha, Sanghoon Song, Nak Cheon Jeong, Ross Harder, Kyung Byung Yoon, Ian K Robinson and Hyunjung Kim Coherence properties of the European XFEL G Geloni, E Saldin, L Samoylova, E Schneidmiller, H Sinn, Th Tschentscher and M Yurkov Fresnel coherent diffractive imaging: treatment and analysis of data G J

  2. Editorial: Focus on Dynamics and Thermalization in Isolated Quantum Many-Body Systems

    Science.gov (United States)

    Cazalilla, M. A.; Rigol, M.

    2010-05-01

    understand many-body quantum systems. This focus issue of New Journal Physics brings together both experimentalists and theoreticians working on these problems to provide a comprehensive picture of the state of the field. Focus on Dynamics and Thermalization in Isolated Quantum Many-Body Systems Contents Spin squeezing of high-spin, spatially extended quantum fields Jay D Sau, Sabrina R Leslie, Marvin L Cohen and Dan M Stamper-Kurn Thermodynamic entropy of a many-body energy eigenstate J M Deutsch Ground states and dynamics of population-imbalanced Fermi condensates in one dimension Masaki Tezuka and Masahito Ueda Relaxation dynamics in the gapped XXZ spin-1/2 chain Jorn Mossel and Jean-Sébastien Caux Canonical thermalization Peter Reimann Minimally entangled typical thermal state algorithms E M Stoudenmire and Steven R White Manipulation of the dynamics of many-body systems via quantum control methods Julie Dinerman and Lea F Santos Multimode analysis of non-classical correlations in double-well Bose-Einstein condensates Andrew J Ferris and Matthew J Davis Thermalization in a quasi-one-dimensional ultracold bosonic gas I E Mazets and J Schmiedmayer Two simple systems with cold atoms: quantum chaos tests and non-equilibrium dynamics Cavan Stone, Yassine Ait El Aoud, Vladimir A Yurovsky and Maxim Olshanii On the speed of fluctuations around thermodynamic equilibrium Noah Linden, Sandu Popescu, Anthony J Short and Andreas Winter A quantum central limit theorem for non-equilibrium systems: exact local relaxation of correlated states M Cramer and J Eisert Quantum quench dynamics of the sine-Gordon model in some solvable limits A Iucci and M A Cazalilla Nonequilibrium quantum dynamics of atomic dark solitons A D Martin and J Ruostekoski Quantum quenches in the anisotropic spin-1⁄2 Heisenberg chain: different approaches to many-body dynamics far from equilibrium Peter Barmettler, Matthias Punk, Vladimir Gritsev, Eugene Demler and Ehud Altman Crossover from adiabatic to sudden

  3. Hubble and ESO's VLT provide unique 3D views of remote galaxies

    Science.gov (United States)

    2009-03-01

    one or several electrons. This is normally due to the presence of very hot, young stars. However, even after staring at the region for more than 11 days, Hubble did not detect any stars! "Clearly this unusual galaxy has some hidden secrets," says Mathieu Puech, lead author of one of the papers reporting this study. Comparisons with computer simulations suggest that the explanation lies in the collision of two very gas-rich spiral galaxies. The heat produced by the collision would ionise the gas, making it too hot for stars to form. Another galaxy that the astronomers studied showed the opposite effect. There they discovered a bluish central region enshrouded in a reddish disc, almost completely hidden by dust. "The models indicate that gas and stars could be spiralling inwards rapidly," says Hammer. This might be the first example of a disc rebuilt after a major merger (ESO 01/05). Finally, in a third galaxy, the astronomers identified a very unusual, extremely blue, elongated structure -- a bar -- composed of young, massive stars, rarely observed in nearby galaxies. Comparisons with computer simulations showed the astronomers that the properties of this object are well reproduced by a collision between two galaxies of unequal mass. "The unique combination of Hubble and FLAMES/GIRAFFE at the VLT makes it possible to model distant galaxies in great detail, and reach a consensus on the crucial role of galaxy collisions for the formation of stars in a remote past," says Puech. "It is because we can now see how the gas is moving that we can trace back the mass and the orbits of the ancestral galaxies relatively accurately. Hubble and the VLT are real ‘time machines' for probing the Universe's history", adds Sébastien Peirani, lead author of another paper reporting on this study. The astronomers are now extending their analysis to the whole sample of galaxies observed. "The next step will then be to compare this with closer galaxies, and so, piece together a picture of

  4. PREFACE: Ultrathin layers of graphene, h-BN and other honeycomb structures Ultrathin layers of graphene, h-BN and other honeycomb structures

    Science.gov (United States)

    Geber, Thomas; Oshima, Chuhei

    2012-08-01

    Kusunoki Mechanical exfoliation of epitaxial graphene on Ir(111) enabled by Br2 intercalationCharlotte Herbig, Markus Kaiser, Nedjma Bendiab, Stefan Schumacher, Daniel F Förster, Johann Coraux, Klaus Meerholz, Thomas Michely and Carsten Busse Low energy electron microscopy and photoemission electron microscopy investigation of grapheneK L Man and M S Altman Periodic overlayers and moiré patterns: theoretical studies of geometric propertiesKlaus Hermann Silicene structures on silver surfacesHanna Enriquez, Sébastien Vizzini, Abdelkader Kara, Boubekeur Lalmi and Hamid Oughaddou Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopyS Koch, M Langer, S Kawai, E Meyer and Th Glatzel Probing the electronic structure and optical response of a graphene quantum disk supported on monolayer grapheneWu Zhou, Stephen J Pennycook and Juan-Carlos Idrobo Multi-oriented moiré superstructures of graphene on Ir(111): experimental observations and theoretical modelsLei Meng, Rongting Wu, Lizhi Zhang, Linfei Li, Shixuan Du, Yeliang Wang and H-J Gao The physics of epitaxial graphene on SiC(0001)H Kageshima, H Hibino and S Tanabe

  5. New Quasar Studies Keep Fundamental Physical Constant Constant

    Science.gov (United States)

    2004-03-01

    from the Oklo natural reactor. Nevertheless, further progress in this field is expected with the new very-high-accuracy radial velocity spectrometer HARPS on ESO's 3.6-m telescope at the La Silla Observatory (Chile). This spectrograph works at the limit of modern technology and is mostly used to detect new planets around stars other than the Sun - it may provide an order of magnitude improvement on the determination of the variation of alpha. Other fundamental constants can be probed using quasars. In particular, by studying the wavelengths of molecular hydrogen in the remote Universe, one can probe the variations of the ratio between the masses of the proton and the electron. The same team is now engaged in such a large survey with the Very Large Telescope that should lead to unprecedented constraints on this ratio. More Information The research presented in this Press Release is based on papers published in Physical Review Letters ("Limits on the time variation of the electromagnetic fine-structure constant in the low energy limit from absorption lines in the spectra of distant quasars" by Raghunathan Srianand, Hum Chand, Patrick Petitjean, and Bastien Aracil) and in the leading European astronomy journal Astronomy & Astrophysics ("Probing the cosmological variation of the fine-structure constant: Results based on VLT-UVES sample" by Hum Chand, Raghunathan Srianand, Patrick Petitjean, and Bastien Aracil).

  6. 6th International Symposium on Molecular Allergology (ISMA

    Directory of Open Access Journals (Sweden)

    Christiane Hilger

    2016-10-01

    diagnostic sensitivity of recombinant Api m 1 and Ves v 5 in diagnosis of Hymenoptera venom allergy Mira Silar, Julij Selb, Rok Kogovsek, Mitja Kosnik, Peter Korosec P45 Added value of biomarkers of primary sensitization and cross-reactivity in patients with hymenoptera venom allergy Leticia Pestana, Alcinda Campos Melo, Ana Mendes, Maria Elisa Pedro, Manuel Pereira Barbosa, Maria Conceição Pereira Santos P46 Cosensitization to Alt a 1 and Act d 2: more than a fortuitous association? Françoise Bienvenu, Claire Goursaud, Lorna Garnier, Sandrine Jacquenet, Michaël Degaud, Sébastien Viel, Annick Barre, Pierre Rougé, Jacques Bienvenu, Joana Vitte P47 Molecular diagnosis for peanut allergy: ALFA method performs as well as established methods for Ara h 1, Ara h 2, Ara h 6, Ara h 9 and CCD Amel Bensalah, Isabelle Cleach, Laurent Mousseau, Chantal Agabriel, Valérie Liabeuf, Joëlle Birnbaum, Jean-Louis Mège, Joana Vitte P48 Evaluation of a food challenge service in relation to specific IgE to molecular components in children with suspected peanut allergy James Gardner, Minal Gandhi, Harsha Kariyawasam, Giuseppina Rotiroti P49 Component resolved diagnosis in cereal allergy Isabel Carrapatoso, Celso Pereira, Frederico Regateiro, Emília Faria, Ana Todo-Bom Poster Session 6: Molecular diagnosis in prevention and therapy P50 Pretreatment molecular sensitizations determine the sIgG4 induction during the updosing of SCIT and may be useful to identify clinically relevant additional sensitizations Johannes Martin Schmid, Ronald Dahl, Hans Juergen Hoffmann P51 Usefulness of recombinant latex allergens in immunotherapy’s decision and follow-up Inês Mota, Filipe Benito Garcia, Angela Gaspar, Mário Morais-Almeida P52 Omega-5-gliadin in the diagnosis of wheat-dependent anaphylaxis induced by ibuprofen but not by exercise Joana Cosme, Letícia Pestana, Amélia Spínola Santos, Manuel Pereira Barbosa P53 Food dependent exercise-induced anaphylaxis: a component-resolved and in vitro