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Sample records for basis relevanter biophysikalischer

  1. Biophysikalische Untersuchungen an bakteriellen Modellmembranen bezüglich ihrer lateralen Organisation und der Interaktion mit humanen β-Defensinen

    OpenAIRE

    Böhling, Arne

    2007-01-01

    Die Zellhülle Gram-negativer Bakterien besteht aus zwei Membranen. Die äußere Membran steht dabei im Fokus dieser Arbeit. Die Lipidmatrix der äußeren Membran besteht aus einer Phospholipidmischung im Fall der inneren Monoschicht und aus Lipopolysacchariden im Fall der äußeren Monoschicht. Die Zellhülle von Mykobakterien, dem Auslöser der Tuberkolose, ist noch nicht vollständig bekannt. Ausgehend von einem in der Zellhülle vorkommenden Lipid, wurden erste biophysikalische Untersuchungen durchg...

  2. Mikroskopische und spektroskopische Charakterisierung biologisch relevanter Oberflächen

    OpenAIRE

    Strehle, Marion A.

    2003-01-01

    In dieser Arbeit werden biologisch relevante Oberflächen untersucht, die in der Medizin bzw. in der Biologie eine wichtige Rolle spielen. Die Proteinadsorption auf Implantat-Oberflächen wurde charakterisiert, um wichtige Informationen über den Adsorptionsprozess zu erhalten. Das Fernziel hierbei ist, durch ein umfassendes Wissen über diesen für die Implantation wichtigen Schritt Biomaterialien mit möglichst hoher Gewebeverträglichkeit zu entwickeln. Die Verteilung von Propolis auf der Wachs-O...

  3. Spektroskopische Bestimmung biophysikalischer Parameter humanen Blutes

    OpenAIRE

    Meinke, Martina

    2010-01-01

    In this work the optical parameters absorption coefficient, scattering coefficient and phase function of blood and its components were investigated, which are useful for optical methods in both diagnostics and therapy. They serve to calculate the dose of light-tissue interaction and permit new optical measuring methods and devices to be developed. So, it was possible to develop new non-invasive blood monitoring procedures of high clinical relevance, including procedures for online determinati...

  4. Características relevantes para el aprendizaje efectivo de una lengua extranjera

    OpenAIRE

    Juan Rubio, Antonio Daniel; García Conesa, Isabel María

    2012-01-01

    [SPA]Este artículo tiene la finalidad de detallar todos los factores o características relevantes a tener en cuenta cuando pretendemos enseñar a los estudiantes, bien a un nivel de primaria, bien a un nivel de secundaria, sobre todo en el aprendizaje de una lengua extranjera, que normalmente suele ser el inglés. Con el fin de esclarecer un tanto los diversos factores que intervienen en el proceso de enseñanza-aprendizaje, uno de los principales objetivos de este estudio era analizar algun...

  5. Análisis comparativo de las variables más relevantes para el desarrollo

    OpenAIRE

    Roberto Jiménez Gómez; Joan Pamela Pan Sanabria

    2012-01-01

    Resumen En este artículo se analiza la evolución histórica de variables que han sido consideradas como relevantes para el desarrollo de Brasil, Chile, Corea del Sur, Finlandia e Irlanda, países donde en las últimas décadas se ha realizado una serie de transformaciones de índole social y económica que son interesantes contrastar con el desarrollo seguido por Costa Rica. A través de un análisis comparativo con estos países, se trata de identificar las lecciones aprendidas y las diferencias entr...

  6. Contabilidade: aspectos relevantes da epopéia de sua evolução

    Directory of Open Access Journals (Sweden)

    Sérgio de Iudícibus

    2005-08-01

    Full Text Available Trata o presente ensaio, como objetivo principal, de aspectos relevantes da epopéia da evolução da Contabilidade, através das várias fases históricas de seu desenvolvimento, desde o estado de simples método de escrituração baseado nas partidas dobradas até sua maturação como ciência social aplicada de forte fundo econômico. Ao longo do trabalho são analisados os vários enfoques, abordagens e teorias, bem como circunstâncias históricas e outras que possam explicar a Contabilidade enquanto ciência genuinamente social. Na interpretação mais atualizada dessa disciplina, a cientificidade contábil deve ser procurada, preferencialmente, numa série de características como, por exemplo: no entendimento e mensuração aplicados aos elementos do patrimônio; na preponderância do valor econômico em lugar de simples custos ou preços; no caráter preditivo das demonstrações contábeis; na introdução do fator risco e do conceito do valor do dinheiro no tempo nas avaliações contábeis, bem como na consideração de custos imputados e de oportunidade etc. A Contabilidade pontifica pela observação das características anteriormente vistas e pela incorporação, em seu arcabouço conceitual, da premissa da prevalência da essência sobre a forma, no campo do conhecimento social aplicado, de natureza econômico-financeira, com ramificações nas áreas de produtividade, ambiental e social e com evidentes conotações quantitativas quanto à sua mecânica patrimonial. É claro que, para efeito de pesquisa e para realçar certas dimensões, a Contabilidade pode ser estudada sob as mais variadas ênfases, como a ética, a macroeconômica, a institucional e social, a comportamental, a sistêmica e a histórica, entre outras, só que a Contabilidade é muito mais que qualquer dessas suas abordagens individualmente tomadas. No fundo, um dos objetivos deste trabalho é, também, subsidiariamente, o de ajudar a responder, pelo menos em

  7. Contabilidade: aspectos relevantes da epopéia de sua evolução

    OpenAIRE

    Sérgio de Iudícibus; Eliseu Martins; L. Nelson Carvalho

    2005-01-01

    Trata o presente ensaio, como objetivo principal, de aspectos relevantes da epopéia da evolução da Contabilidade, através das várias fases históricas de seu desenvolvimento, desde o estado de simples método de escrituração baseado nas partidas dobradas até sua maturação como ciência social aplicada de forte fundo econômico. Ao longo do trabalho são analisados os vários enfoques, abordagens e teorias, bem como circunstâncias históricas e outras que possam explicar a Contabilidade enquanto ciên...

  8. Revisión de algunas variables relevantes en el establecimiento de metas deportivas

    Directory of Open Access Journals (Sweden)

    Jaime Díaz-Ocejo

    2013-01-01

    Full Text Available El propósito del presente trabajo es examinar la influencia de algunas variables relevantes en el proceso de establecimiento de metas, como son la proximidad, la especificidad, la dificultad y la efectividad de las mismas, a través de la revisión de la literatura científica al respecto. Para ello, se siguen las directrices señaladas por autores destacados en este ámbito de estudio. Los resultados de la revisión no revelan posturas concluyentes en relación a la influencia de la proximidad, la especificidad y la dificultad de las metas. Contrariamente, se encuentran evidencias más consistentes a favor de la efectividad del empleo de esta estrategia psicológica como herramienta para la mejora del rendimiento en distintas tareas motoras.

  9. ESTUDIO DE ASPECTOS RELEVANTES DE LOS HABITANTES DE CAZUCÁ (SECTOR 4

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    Gregorio Clavijo Parrado

    2007-01-01

    Full Text Available Esta investigación de tipo descriptivo tuvo como objetivo general el acercamiento a la realidad social, económi - ca y demográfica de un sector de la comunidad de Cazucá, en aspectos considerados relevantes, tales como: vivienda, educación, ocupación, ingresos, gastos, edad y otros. Aunque la observación de campo se realizó en el sector cuatro de Cazucá (Soacha/Cundinamarca, se podría considerar como una muestra representativa de lo que podría estar sucediendo con el total de la comunidad. Dadas las características socioeconómicas de las familias, como unidades de observación, los resultados de - tectaron su vulnerabilidad a través de dimensiones tangibles y no tangibles relacionadas con la pobreza que, posteriormente, podrían ser objeto de indagación más profunda. Los resultados se socializarán con la comunidad y con las entidades y organismos que en Cazucá están o estén adelantando programas culturales, educativos, microempresariales y otros.

  10. Análisis comparativo de las variables más relevantes para el desarrollo

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    Roberto Jiménez Gómez

    2012-07-01

    Full Text Available Resumen En este artículo se analiza la evolución histórica de variables que han sido consideradas como relevantes para el desarrollo de Brasil, Chile, Corea del Sur, Finlandia e Irlanda, países donde en las últimas décadas se ha realizado una serie de transformaciones de índole social y económica que son interesantes contrastar con el desarrollo seguido por Costa Rica. A través de un análisis comparativo con estos países, se trata de identificar las lecciones aprendidas y las diferencias entre los indicadores de las variables estudiadas para inferir algunas conclusiones de su evolución en el largo plazo y su implicación en el desarrollo de los países en cuestión. Palabras Claves: Desarrollo, ingreso nacional bruto, competitividad, educación, desarrollo humano. Abstract This article analyzes the historical evolution of some variables that have been considered as relevant to the development of Brazil, Chile, South Korea, Finland and Ireland, which in recent decades made transformations on social, economic and a combination of both fields that can serve as a guide for other developing countries like Costa Rica. Through a comparative analysis of these countries, will be possible to take a note about the lessons learned and the differences between the selected indicators, and in fact, this scenario reflects the changes made and the position where you will find the country. Keywords: Development, GNI, competitiveness, education, human development.

  11. El concepto de desarrollo: posiciones teóricas más relevantes

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    Norbis Mujica Chirinos

    2010-01-01

    Full Text Available El resurgimiento de la discusión acerca de los modelos de desarrollo se puede ubicar hacia finales de la década de los noventa, cuando se hizo más que evidente que las medidas de ajuste ortodoxas aplicadas en América Latina en particular, no alcanzaron los resultados esperados, lo que generó dudas sobre la concepción y orientación que guiaron estos procesos. Hoy, en el marco de la crisis financiera global y del sistema capitalista en general, el tema vuelve a colocarse en el tapete. En este sentido, el presente artículo tiene como objetivo analizar el concepto de desarrollo desde las posiciones teóricas más relevantes en la segunda mitad del siglo XX y comienzos del XXI. La metodología utilizada para abordar el estudio fue la revisión y análisis teórico, el análisis de contenido y el análisis biblio-hemerográfico, previéndose un horizonte temporal entre 1960 y 2008, centrándose el análisis en los modelos operacionalizados en este periodo, además de incluir otros enfoques alternativos, dada su importancia teórica y epistémica. Los resultados evidencian que ha existido un marcado énfasis economicista alrededor de la idea de crecimiento económico como expresión de desarrollo, lo que ha motivado algunas respuestas desde otros ángulos. Se concluye en la necesidad de concebir el desarrollo como un proceso altamente complejo, que exige la integración de diversos factores que contribuyan a enriquecer el concepto e impacten las políticas y los actores involucrados en el mismo.

  12. Brancheindsats for jern- og metalstøberier: Fase 2.1 Udvælgelse af relevante processer

    DEFF Research Database (Denmark)

    Tiedje, Niels; Frees, Niels; Olsen, Stig Irving

    Dette er en delrapportering af brancheindsatsens fase 2.1, som er udvælgelse af relevante støbeprocesser til UMIP databasen. Processerne er udvalgt og prioriteret ud fra et overblik over processer på danske jern- og metalstøberier, besøg på en række virksomheder, indledende miljøvurdering af 2 st...

  13. ENVEJECIMIENTO COGNITIVO Y PROCESAMIENTO DEL LENGUAJE: CUESTIONES RELEVANTES COGNITIVE AGING AND LANGUAGE PROCESSING: RELEVANT ISSUES

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    MÓNICA VÉLIZ

    2010-01-01

    Full Text Available ¿Qué sucede con el lenguaje cuando se envejece? ¿Se produce una declinación de las habilidades lingüísticas? ¿Cambian los patrones de desempeño de los mayores si se los compara con los jóvenes? ¿Qué variables pueden explicar los cambios que se producen? Para dar respuesta a estas y otras interrogantes se presentan las teorías más revelantes que se han desarrollado para dar cuenta de los efectos del envejecimiento cognitivo en los procesos de comprensión y producción del lenguaje, a saber: enlentecimiento, déficit inhibitorio, déficit de transmisión, reducción de la memoria operativa. Se hace también una revisión de los hallazgos más relevantes de la investigación psicolingüística de orientación gerontológica. El examen abarca todos los niveles de procesamiento y considera los fenómenos de comprensión y de producción vinculados a la palabra, la oración y el discurso. El análisis del problema se completa presentando aportes provenientes de la neuropsicología y discutiendo cuestiones críticas relacionadas con los métodos de investigación que se usan en el área y el papel que juegan los factores culturales y sociales.What happens to language when humans age? Is there a decline in the language abilities in old age? Do performance patterns in the elderly change when compared to those of younger individuals? What variables can explain these changes? In order to answer these and other questions, the authors present the most relevant theories developed to explain age-related cognitive effects in language comprehension and production processes, for instance slowing, inhibitory deficit, transmission deficit, working memory decline. Furthermore the most notable findings of gerontology-based psycholinguistic research are reviewed, covering all language processing levels. It also takes into account the language comprehension and production phenomena regarding word, sentence and discourse levels. The problem analysis is

  14. Factores relevantes de la Calidad de Vida Docente de los profesores de la UASD: Un estudio exploratorio

    OpenAIRE

    Ureña Ramírez, Ana Jacqueline

    2015-01-01

    El objetivo fundamental de esta investigación consistió en identificar los factores relevantes de la calidad de vida docente de los profesores de la Universidad Autónoma de Santo Domingo considerando la personalidad, satisfacción, burnout y valores y con las variables sociodemográficas edad, sexo, los años trabajando en la universidad, la cantidad de grupos a los que da clases, las horas dedicas a la institución, las horas dedicadas fuera a otras actividades laborales y total de horas traba...

  15. Basis Entropy

    OpenAIRE

    Chen, Xing

    2016-01-01

    Projective measurement can increase the entropy of a state $\\rho$, the increased entropy is not only up to the basis of projective measurement, but also has something to do with the properties of the state itself. In this paper we define this increased entropy as basis entropy. And then we discuss the usefulness of this new concept by showing its application in explaining the success probability of Grover's algorithm and the existence of quantum discord. And as shown in the paper, this new co...

  16. Atributos Relevantes de Destinos Turísticos na Percepção de Internautas Brasileiros

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    Iomara Scandelari Lemos

    2010-09-01

    Full Text Available Resumo Este artigo objetiva identificar, na percepção do turista brasileiro, a estrutura subjacente da importância de atributos que caracterizam os destinos turísticos. Trata-se de uma pesquisa do tipo survey disponibilizada em website e respondida por 471 internautas brasileiros. Utilizaram-se procedimentos estatísticos de análise fatorial; validade de construto; construção de escalas e análise fatorial confirmatória com modelagem de equações estruturais. Conclui-se que, tomados isoladamente, os atributos considerados mais relevantes foram: sensação de segurança; qualidade do aspecto visual do destino; sensação de não estar sendo explorado e facilidade de acesso ao destino turístico, totalizando 70,5% das respostas. Contudo, analisados em conjunto, três fatores respondem por 62,2% da variância explicada. Palavras-chave: análise fatorial; modelagem de equação estrutural; atributos relevantes de turismo. Abstract This article aims to identify, in the perception of Brazilian tourists, the subjacent structure of the importance of attributes that characterize the tourist places destinations. This research is a survey available on website and answered by 471 Brazilians internet users. It used statistical procedures such as factorial analysis, construct reliability, construction of scales and structural equation modeling for confirmatory factorial analysis. It was concluded that, taken alone, the attributes considered most important were: sensation of visiting a safety place, visual aspect quality of the tourism destination areas, sensation of not being exploited and facilities concerned to the tourism destination areas. These totalized 70.5% of responses. However, taken together, three factors account for 62.2% of variance explained. Keywords: factorial analysis; structural equation modeling; tourism's relevant attributes.

  17. Estudio de las destrezas expresivas de comunicación oral relevantes para el desempeño profesional: Implicaciones sobre el currículo comunicativo

    OpenAIRE

    Briz Villanueva, Ezequiel; Mendoza Fillola, Antonio; Orejudo Hernández, Santos

    2014-01-01

    Se presenta esta tesis doctoral titulada: Estudio de las destrezas expresivas de comunicación oral relevantes para el desempeño profesional. Implicaciones sobre el currículo comunicativo. El objetivo perseguido es conocer el punto de vista de las organizaciones de trabajo acerca del nivel de competencia de comunicación oral con que acceden los empleados a las mismas, identificar las habilidades y destrezas más relevantes para el empleo, detectar las carencias y necesidades de formación y, fin...

  18. Los cinco sexos, o cómo establecemos fronteras categoriales moralmente relevantes en un mundo difuso y continuo

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    Gomila, Antoni

    2013-08-01

    Full Text Available It is generally assumed that moral realism requires a determined world, so that moral judgments can also be determined. From this point of view, genuine moral dilemmas, where two alternative judgments are equally well-grounded, would be a counter-example for moral realism. In this paper I argue against such a challenge to moral realism. Starting from the continuous and gradualist character of the constitutive criteria of our concepts, I show how indeterminacies and limit cases are to be expected where it can be impossible to determine the truth value of a proposition. The existence of fuzzy conceptual boundaries does not mean they cannot be crossed (that they are not useful, that they do not capture difference or relevant features from the point of view of the causal structure of reality and its intelligibility, quite the opposite: they serve to establish morally relevant differences. The very possibility of a community with common conceptual practices depends upon the existence of paradigmatic, central cases that exemplify a concept meaning or a moral valuation.Generalmente se considera que el realismo moral exige un mundo bien determinado, para que las valoraciones también puedan estarlo. Desde este punto de vista, los dilemas morales genuinos, donde no pueda establecerse la opción moralmente correcta porque haya razones igualmente poderosas para ambas alternativas, constituyen un desafío al realismo moral. En este trabajo argumento en contra de este tipo de ataque al realismo moral. Partiendo del carácter continuo y gradual de los criterios constitutivos de nuestros conceptos, muestro cómo cabe esperar precisamente casos límite, en los que aparentemente está indeterminada la verdad. Que existan fronteras conceptuales borrosas no significa que no puedan ser cruzadas (que no sean útiles, que no capten diferencias o aspectos relevantes desde el punto de vista de la estructura causal de la realidad y su inteligibilidad, al contrario

  19. Factores relevantes de la complejidad en el proceso de remanufactura: caso de la industria metalmecánica

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    Karina Cecilia Arredondo Soto

    2014-06-01

    Full Text Available Este artículo presenta los resultados de un proyecto realizado en el sector de remanufactura, abordando la gestión de la complejidad. El objetivo de la investigación es identificar los factores que crean complejidad en el proceso de producción. El grado de complejidad asociado a los procesos de remanufactura es superior que en la manufactura convencional. El estudio se realiza en la frontera norte de México analizando las prácticas de tres compañías del área metalmecánica y aplica una metodología alemana para la identificación de las características más importantes y efectos de la complejidad. Los resultados permiten seleccionar los factores relevantes de complejidad que intervienen y que pueden ser controlados por tomadores de decisiones para mejorar los indicadores de desempeño en el sector industrial remanufacturero.

  20. Razonamiento e inferencia relevante

    OpenAIRE

    Peña, Lorenzo

    1998-01-01

    Hay dos enfoques principales de una teoría de racionalidad: el positivo y el negativo. Éste se preocupa de rechazar lo que sea irracional. El positivo se propone estudiar el razonamiento y, en la medida de lo posible, mejorar los patrones o las pautas de nuestro razonamiento práctico. Para el enfoque negativo, la inconsistencia es la más común prueba de irracionalidad. Raras veces se dan cuenta sus heraldos de que hay lógicas alternativas a cuyo tenor...

  1. Aspectos relevantes para identificação da claudicação intermitente Aspectos relevantes para la identificación de la claudicación intermitente Aspects relevant to the identification of intermittent claudication

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    Rita de Cassia Gengo e Silva

    2011-01-01

    Full Text Available A claudicação intermitente (CI é uma das características definidoras aprovadas pela North American Nursing Diagnosis Association - International (NANDA-I para o diagnóstico de enfermagem Perfusão Tissular Periférica Ineficaz. Para a correta identificação dessa característica definidora, o enfermeiro deve conhecer suas características clínicas e possuir habilidades propedêuticas específicas. O objetivo deste artigo foi destacar os aspectos relevantes para identificação da CI durante aanamnese e o examw físico realizado pela enfermeira. Com base nas diretrizes específicas e outras publicações sobre o tema, foram descritas as características clínicas da CI e sua diferenciação de outros fenômenos álgicos que acometem os membros inferiores. Foram apresentado questionários para a rastreabilidade da CI, busca de alterações no exame físico, que podem acompanhar o sintoma e a avaliação por meio do índice tornozelo-braquial.La claudicación intermitente (CI es una de las características definidoras aprobadas por la North American Nursing Diagnosis Association - International (NANDA-I para el diagnóstico de enfermería Perfusión Tisular Periférica Ineficaz. Para la correcta identificación de esa característica definidora, el enfermero debe conocer sus características clínicas y poseer habilidades propedéuticas específicas. El objetivo de este artículo fue destacar los aspectos relevantes para la identificación de la CI durante la anamnesis y el examen físico realizado por la enfermera. Con base en las directrices específicas y otras publicaciones sobre el tema, fueron descritas las características clínicas de la CI y su diferenciación de otros fenómenos álgicos que afectan a los miembros inferiores. Fueron presentados cuestionarios para el rastreamiento de la CI, búsqueda de alteraciones en el examen físico, que pueden acompañar al síntoma y la evaluación por medio del índice tobillo

  2. A gerontologia e a interdisciplinaridade: aspectos relevantes para a enfermagem La gerontología e interdisciplinaridade: los aspectos relevantes para la enfermería Gerontology and interdisciplinarity: relevant aspects to nursing

    Directory of Open Access Journals (Sweden)

    Alessandra Conceição Leite Funchal Camacho

    2002-04-01

    Full Text Available Este artigo retrata a Gerontologia como área rica e cheia de lacunas a serem preenchidas pelas disciplinas que a compõem, indo além das abordagens convencionais à clientela idosa, visando a caminhos renovados para a Enfermagem, que, dentre tantas disciplinas, também está no processo construtivo de conhecimento. Tem como objetivo destacar a importância da Gerontologia para a atuação interdisciplinar, principalmente para Enfermagem, ressaltando o cliente idoso no contexto social. A interdisciplinaridade é instrumento condutor para Gerontologia em busca de mudanças que venham a somar conhecimentos e redundar em esforços no processo de desenvolvimento da área da saúde em relação ao cliente idoso e às diversas disciplinas que contemplam uma atuação relevante que, sem dúvida, permitem avanços para a Enfermagem.Este artículo retrata la Gerontología como área rica y llena de lagunas para ser resueltas por las disciplinas que la componen, yendo más allá de los abordajes convencionales a la población anciana, buscando caminos renovados para enfermería, que dentro de tantas disciplinas, también está en el proceso constructivo del conocimiento. Tiene como objetivo destacar la importancia de la gerontología para la actuación interdisciplinaria, principalmente para enfermería, resaltando al paciente anciano en el contexto social. La interdisciplinariedad La interdisciplinariedad es instrumento conductor para la Gerontología en busca de cambios que vengan a agregar conocimientos que redunden en esfuerzos para el proceso de desarrollo del área de la salud en relación con el cliente anciano, y las diversas disciplinas que contemplan una actuación relevante que, sin duda, permitan avances para enfermería.This article shows Gerontology as a rich area and full of gaps to be filled by the disciplines that form it, going beyond the conventional approaches to the elderly client and aiming at finding new Nursing paths as, among

  3. Características relevantes de la simulación energética de viviendas unifamiliares

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    García-Alvarado, R.

    2014-03-01

    Full Text Available Energy simulation systems allow analyzing the environmental quality and demand of buildings, but they must have reliable and proper procedures. This paper identifies relevant conditions of energy simulation systems for the study of single-family homes, based on the analysis of a dozen programs and various experiences in south central Chile. A review of capabilities was conducted, simulating the same case in all systems and making interviews with expert users. Besides it studied the incidence of background data and different strategies for analysis the environmental performance of housing. Revealing significant characteristics in the energy study of detached residential buildings. Finally it suggests reviewing certain conditions to ensure the effectiveness of the environmental analysis and subsequent actions.Los sistemas de simulación energética de edificios permiten analizar la calidad y demanda ambiental de las construcciones, pero deben contar con procedimientos fiables y pertinentes. Este artículo identifica condiciones relevantes de la simulación energética de viviendas unifamiliares, basado en el análisis de una docena de programas y distintas experiencias en el centro sur de Chile. Desarrollando una revisión de capacidades de los sistemas, a través de la simulación de una misma vivienda y entrevistas a usuarios expertos. Además de estudiar incidencias de los antecedentes y distintas estrategias de análisis para el mejoramiento ambiental de viviendas. Revelando características significativas para el estudio energético de construcciones habitacionales aisladas. Finalmente sugiere revisar ciertas condiciones de los sistemas para asegurar la efectividad de los análisis ambientales y de las acciones subsecuentes.

  4. Selection and examination of types of waste relevant to underground disposal. Final report; Auswahl und Untersuchung UTD-relevanter Abfallarten. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Reichelt, C. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Braunschweig (Germany). Inst. fuer Tieflagerung; Brasser, T. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Braunschweig (Germany). Inst. fuer Tieflagerung; Bahadir, M. [Technische Univ. Braunschweig (Germany). Inst. fuer Oekologische Chemie und Abfallanalytik; Fischer, R. [Technische Univ. Braunschweig (Germany). Inst. fuer Oekologische Chemie und Abfallanalytik; Lorenz, W. [Technische Univ. Braunschweig (Germany). Inst. fuer Oekologische Chemie und Abfallanalytik; Petersen, C. [Technische Univ. Braunschweig (Germany). Inst. fuer Oekologische Chemie und Abfallanalytik

    1995-12-31

    In order to do justice to the principle laid down in the Waste Management Technical Code that wastes disposed of underground in salt rock formations should remain clear of the biosphere for an indefinite time and without the need for later remedial measures and in order to realise the concept of so-called pollution-free disposal (mainly in non-saline formations) it is necessary to have verified knowledge on the types of waste concerned, the geological and hydrogeological conditions at the disposal site and in its surroundings, and on the future development of the entire disposal system. The long-term safety of a disposal site (or that of any kind of underground disposal of materials) depends on whether water or aqueous solutions can act on the host rock or on the wastes deposited in it, the extent to which this can result in dissolving processes and/or contaminant mobilisation and, finally, on whether this can conceivably lead to an impairment of the intended barriers and to a disposal of contaminants in the nearer or farther surroundings of the underground disposal site. This means in particular that the wastes themselves and their reactivity with fluid components in geological systems must be well-known or else examined and duly assessed. The following final report therefore is intended as a contribution to creating the requisite database for types of waste relevant to underground disposal. It has been possible here to collect important information on arising waste quantities and critical waste constituents and assess their hazard potential and so provide a basis for further research and development work. (orig./SR) [Deutsch] Der in der TA Abfall formulierte Grundsatz, bei der Ablagerung von Abfaellen in untertaegigen Anlagen im Salzgestein die Abfaelle dauerhaft und nachsorgefrei von der Biosphaere fernzuhalten, wie auch die Realisierung des Konzeptes der sog. immissionsneutralen Ablagerung (vornehmlich in nichtsalinaren Formationen) erfordern gesicherte

  5. ¿Cómo se traduce el curriculum formal en una experiencia escolar relevante para los alumnos de una escuela telesecundaria de México?

    Directory of Open Access Journals (Sweden)

    José de la luz Sánchez Tepatzi

    2011-01-01

    Full Text Available En este artículo se presenta parte de los resultados obtenidos en una investigación realizada entre los años 2009 y 2010 en una comunidad rural en México donde participaron 12 personas que abandonaron la escuela tele-secundaria. El estudio es de tipo cualitativo y las principales herramientas para obtener la información fueron la historia de vida y la entrevista abierta. La pregunta que orienta este artículo analiza las formas en cómo los alumnos traducen el curriculum formal en una experiencia escolar relevante y cómo influye tal significado en la permanencia. Los principales resultados señalan que la relación profesor-alumno, el trato entre pares y el apoyo de la familia, son elementos importantes para mejorar la permanencia y la calidad de los aprendizajes, así como para otorgar significado relevante a esa experiencia. En las conclusiones del estudio se muestra que el valor positivo hacia la escuela y la relevancia de la experiencia escolar, no son elementos suficientes para garantizar la permanencia, pues en esa decisión intervienen otros factores y razonamientos particulares. Es decir, cada alumno, en su mundo de vida construye un sentido de la realidad y este es el que orienta sus decisiones; una de ellas es permanecer o retirarse de la escuela. En este marco de relativa autonomía, los profesores estamos obligados a ofrecer a los alumnos la oportunidad de vivir una experiencia escolar relevante que les permita desenvolverse en un mundo complejo y aprender a lo largo de la vida, más allá de su condición y disposición para permanecer en la escuela.

  6. BASIS RISK FOR RICE

    OpenAIRE

    Lord, Yoshie Saito; Turner, Steven C.

    1998-01-01

    The objective of this paper is to develop a cross hedging model for rice that minimizes basis risk and accounts for the existence of the nonstationary nature of basis. Basis is treated as an endogenous variable and model for basis risk are developed.

  7. REVISIÓN DE ESTÁNDARES RELEVANTES Y LITERATURA DE GESTIÓN DE RIESGOS Y CONTROLES EN SISTEMAS DE INFORMACIÓN

    OpenAIRE

    MARLENE LUCILA GUERRERO JULIO; LUIS CARLOS GÓMEZ FLÓREZ

    2011-01-01

    La gestión de riesgos y controles en sistemas de información (GRCSI) es una actividad importante en los sistemas de gestión. No obstante, aunque en lasorganizaciones parece haber interés en su aplicación, la GRCSI aún no logra el impacto deseado, debido en gran parte a la falta de entendimiento de su sentido o propósito y a la ausencia de los procesos de cambio organizacional necesarios para su implantación. Este artículo presenta una revisión sobre los estándares de GRCSI más relevantes, con...

  8. Classificação do conteúdo de documentos contábeis usando aprendizagem de máquina: o caso dos fatos relevantes

    Directory of Open Access Journals (Sweden)

    Roberto Ternes Arrial

    2010-08-01

    Full Text Available A análise de conteúdo de textos narrativos tem sido estudada, nos últimos anos, com mais frequência. Em diversos trabalhos, verifica-se a pesquisa com relação a sua legibilidade, compreensibilidade e o nível de otimismo, neutralidade e pessimismo. Porém, a análise de classificação quanto a tendências otimistas, pessimistas e neutras tem sido feita de forma muito trabalhosa, pois demanda uma análise humana dos textos, justificando a criação de uma análise de textos de forma mais rápida e objetiva, além da tentativa de eliminação da subjetividade. Diante disso, o objetivo deste trabalho é propor uma classificação automática de fatos relevantes contábeis, fazendo-se uma análise do conteúdo de textos narrativos, com a utilização de ferramentas computacionais de leitura e classificação de textos. A ideia é procurar contribuir com um exemplo de aplicação de aprendizado de máquina à Ciência Contábil. Esta análise utilizou-se de fatos relevantes já analisados anteriormente no trabalho de Pereira e Silva (2008. Os fatos já classificados foram utilizados como conjunto de treinamento para o programa, para que assim ele pudesse classificar outros dados desconhecidos, não classificados.

  9. Identificación de indicadores relevantes del desempeño rse mediante la utilización de técnicas multicriterio

    Directory of Open Access Journals (Sweden)

    Marta de la Cuesta González

    2015-01-01

    Full Text Available Uno de los principios básicos de la gestión e información reportada en materia de Responsabilidad Social Empresarial (RSE es que se centre en los aspectos relevantes para la sociedad. Adicionalmente, la necesidad de realizar comparaciones entre empresas exige un esfuerzo sintetizador en la rendición de cuentas en RSE. Este trabajo se centra en la aplicación de técnicas de decisión multicriterio, concretamente procesos analíticos jerárquicos, para ofrecer una herramienta que permita medir el desempeño de RSE, con base en aquellos aspectos que son relevantes y materiales para empresas y stakeholders conjuntamente, en un contexto y sociedad determinados. El artículo explica cómo se aplicó la metodología de proceso de análisis jerárquico a una muestra de 10 sujetos (6 empresas españolas y 4 organizaciones de la sociedad civil española en la selección de los indicadores materiales en el reporte de RSE y los resultados alcanzados. Se identificaron 60 indicadores distribuidos en cuatro dimensiones: medioambiente, economía, gobierno corporativo y social. Esta última dimensión concentra el mayor número de indicadores y mezcla impactos sobre diferentes grupos de interés, por lo que es dividida en cuatro subdimensiones (recursos humanos, derechos humanos, responsabilidad del producto y sociedad, con el objeto de discernir con mayor detalle su complejidad.

  10. Basis selection in LOBPCG

    Science.gov (United States)

    Hetmaniuk, U.; Lehoucq, R.

    2006-10-01

    The purpose of our paper is to discuss basis selection for Knyazev's locally optimal block preconditioned conjugate gradient (LOBPCG) method. An inappropriate choice of basis can lead to ill-conditioned Gram matrices in the Rayleigh-Ritz analysis that can delay convergence or produce inaccurate eigenpairs. We demonstrate that the choice of basis is not merely related to computing in finite precision arithmetic. We propose a representation that maintains orthogonality of the basis vectors and so has excellent numerical properties.

  11. Aspectos relevantes dos SAD nas organizações: um estudo exploratório Relevant aspects from DSS in organizations: an empirical investigation

    Directory of Open Access Journals (Sweden)

    Adriana Zenaide Clericuzi

    2006-04-01

    Full Text Available A informação vem auxiliando as organizações a alcançarem seus objetivos num ambiente de crescente concorrência, exigindo delas rapidez, flexibilidade e alta percepção. A abrangência cada vez maior do uso dos Sistemas de Apoio à Decisão (SAD como suporte na solução de problemas tem como proposta o processamento de informação para reduzir a incerteza e resolver conflitos. Este artigo tem como objetivo fazer uma investigação sobre os SAD nas organizações brasileiras. Para tal, foi conduzida uma pesquisa exploratória e descritiva, sobre o assunto, foram utilizados questionários que investigaram os SAD nas empresas brasileiras e aspectos relevantes destes sistemas.Information is supporting organizations to reach theirs objectives. Competition is increasing in organizational environment, requiring capability, flexibility and high perception. Decision Support Systems (DSS are becoming greater as a tool for solution of problems, processing information to reduce uncertain in decision problems and deciding conflicts. The objective of this paper is reports a study about DSS in organizations. For such an empirical investigation of literature in DSS and an empirical research were done. Questionnaires had been used to investigate the relevant aspects of SAD in the Brazilian companies.

  12. Un análisis a los atributos relevantes de los mercados de las pulgas para los compradores: Evidencia desde América Latina

    Directory of Open Access Journals (Sweden)

    Sergio Olavarrieta

    2008-01-01

    Full Text Available Los investigadores de marketing constantemente han estudiado los mercados formales (e.g., supermercados, tiendas por departamento. Sin embargo, pocos estudios de marketing han investigado a los mercados informales (e.g., mercados de las pulgas. Adicionalmente, estos pocos estudios han sido efectuados en países desarrollados. El objetivo principal de este artículo es identificar los atributos relevantes de los mercados de las pulgas para los compradores latinoamericanos. En este trabajo el mercado de las pulgas más visitado en Chile es analizado. Los autores concluyen que los compradores intensivos en mercados de las pulgas consideran al mercado de las pulgas como un lugar agradable para comprar (e.g., servicio amigable, que ofrece una amplia variedad de bienes (e.g., gangas, antigüedades, productos discontinuados y bajos precios; mientras que los compradores menos intensivos tienen inquietudes acerca de los productos (baja calidad, de los servicios (informalidad, suciedad, bajas garantías y de los problemas éticos (evasión de impuestos, bienes robados asociados a los mercados de las pulgas. Estos resultados sugieren que los mercados de las pulgas no compiten directamente con los mercados formales.

  13. Safety Basis Report

    International Nuclear Information System (INIS)

    As part of the internal Integrated Safety Management Assessment verification process, it was determined that there was a lack of documentation that summarizes the safety basis of the current Yucca Mountain Project (YMP) site characterization activities. It was noted that a safety basis would make it possible to establish a technically justifiable graded approach to the implementation of the requirements identified in the Standards/Requirements Identification Document. The Standards/Requirements Identification Documents commit a facility to compliance with specific requirements and, together with the hazard baseline documentation, provide a technical basis for ensuring that the public and workers are protected. This Safety Basis Report has been developed to establish and document the safety basis of the current site characterization activities, establish and document the hazard baseline, and provide the technical basis for identifying structures, systems, and components (SSCs) that perform functions necessary to protect the public, the worker, and the environment from hazards unique to the YMP site characterization activities. This technical basis for identifying SSCs serves as a grading process for the implementation of programs such as Conduct of Operations (DOE Order 5480.19) and the Suspect/Counterfeit Items Program. In addition, this report provides a consolidated summary of the hazards analyses processes developed to support the design, construction, and operation of the YMP site characterization facilities and, therefore, provides a tool for evaluating the safety impacts of changes to the design and operation of the YMP site characterization activities

  14. Safety Basis Report

    Energy Technology Data Exchange (ETDEWEB)

    R.J. Garrett

    2002-01-14

    As part of the internal Integrated Safety Management Assessment verification process, it was determined that there was a lack of documentation that summarizes the safety basis of the current Yucca Mountain Project (YMP) site characterization activities. It was noted that a safety basis would make it possible to establish a technically justifiable graded approach to the implementation of the requirements identified in the Standards/Requirements Identification Document. The Standards/Requirements Identification Documents commit a facility to compliance with specific requirements and, together with the hazard baseline documentation, provide a technical basis for ensuring that the public and workers are protected. This Safety Basis Report has been developed to establish and document the safety basis of the current site characterization activities, establish and document the hazard baseline, and provide the technical basis for identifying structures, systems, and components (SSCs) that perform functions necessary to protect the public, the worker, and the environment from hazards unique to the YMP site characterization activities. This technical basis for identifying SSCs serves as a grading process for the implementation of programs such as Conduct of Operations (DOE Order 5480.19) and the Suspect/Counterfeit Items Program. In addition, this report provides a consolidated summary of the hazards analyses processes developed to support the design, construction, and operation of the YMP site characterization facilities and, therefore, provides a tool for evaluating the safety impacts of changes to the design and operation of the YMP site characterization activities.

  15. Assessment of the failure behavior of dangerous goods containers made of high density polyethylene using relevant material parameters; Beurteilung des Versagensverhaltens von Gefahrengutbehaeltern aus Polyethylen hoher Dichte auf Basis relevanter Werkstoffkennwerte

    Energy Technology Data Exchange (ETDEWEB)

    Menrad, Andreas

    2013-09-01

    To obtain approval as dangerous goods packaging, different experimental tests are required to show the eligibility for the transportation of those goods. The data obtained from the material test performed on the pressed plates is not used to get absolute values for the failure time in an internal pressure test or the medium drop height. The goal is to see if there are changes in the behavior because a different HDPE is being used. All the jerrycans and pressed plates were specially made of four different materials to gain knowledge about the material properties. The plates and jerrycans were made of resin from the same batch to prevent variations caused by batch differences. The wall thickness is decisive and, therefore packagings were analyzed using computer tomography and the fringe projection technique. The results were compared to the magnetostatic measurement technique. The deformation under internal pressure was measured by digital image correlation. Deformations in the radial direction and the equivalent strains were determined. These deformations, strains, and their acceleration due to the swelling effect could be reproduced in the finite element analysis by using the temperature in the material model. The resistance against both internal pressure and absorption depend on the density of the material. Conditioning at elevated temperatures causes post crystallization and reduces internal stresses. Differences in the densities of the materials can be determined by using plates manufactured by compression molding. A higher density leads to a better performance under internal pressure. A correlation could be proved between the medium failure drop height (50 % of the packagings fail because of a crack) and the tensile impact strength of notched specimens cut out of the jerrycans side walls and the notched impact strength (NIS) of pressed plates. A higher NIS leads to a higher medium failure drop height. A low resistance against oxidative degradation will reduce the medium failure drop height drastically. However, materials which are highly resistant to oxidative degradation do not have lower medium failure drop heights after conditioning with nitric acid when compared to non-conditioned jerrycans. The resistance against oxidative degradation can be determined with plates manufactured by compression molding and allow conclusions about changes in medium drop heights.

  16. Basis Tensor Gauge Theory

    CERN Document Server

    Chung, Daniel J H

    2016-01-01

    We reformulate gauge theories in analogy with the vierbein formalism of general relativity. More specifically, we reformulate gauge theories such that their gauge dynamical degrees of freedom are local fields that transform linearly under the dual representation of the charged matter field. These local fields, which naively have the interpretation of non-local operators similar to Wilson lines, satisfy constraint equations. A set of basis tensor fields are used to solve these constraint equations, and their field theory is constructed. A new local symmetry in terms of the basis tensor fields is used to make this field theory local and maintain a Hamiltonian that is bounded from below. The field theory of the basis tensor fields is what we call the basis tensor gauge theory.

  17. Symmetry Adapted Basis Sets

    DEFF Research Database (Denmark)

    Avery, John Scales; Rettrup, Sten; Avery, James Emil

    automatically with computer techniques. The method has a wide range of applicability, and can be used to solve difficult eigenvalue problems in a number of fields. The book is of special interest to quantum theorists, computer scientists, computational chemists and applied mathematicians....... eigenfunctions and eigenvalues for the Hamiltonian of a many-particle system is usually so difficult that it requires approximate methods, the most common of which is expansion of the eigenfunctions in terms of basis functions that obey the boundary conditions of the problem. The computational effort needed...... in such problems can be much reduced by making use of symmetry-adapted basis functions. The conventional method for generating symmetry-adapted basis sets is through the application of group theory, but this can be difficult. This book describes an easier method for generating symmetry-adapted basis sets...

  18. Factores relevantes en complicaciones de fracturas mandibulares: Relato de 5 años Factors relevant to mandibular fracture complications: A 5-year experience

    Directory of Open Access Journals (Sweden)

    E. Serena Gómez

    2009-04-01

    Full Text Available Objetivo: Este estudio ayudará a comprender factores relevantes y su relación con complicaciones post-operatorias en pacientes con tratamiento de fracturas mandibulares. Diseño de estudio: Para el estudio fueron obtenidos datos de pacientes atendidos en un periodo de cinco años por el Área de Cirugía y Traumatología Buco-Maxilofacial de la Facultad de Odontología de Piracicaba, UNICAMP, Brasil. Los datos relevantes de los pacientes en esta investigación fueron; edad, género, actividad económica, consumo de sustancias, etiología del trauma, demora de tratamiento de fractura, tipo de fractura mandibular, complicación post-operatoria y tratamiento a la complicación. Resultados: Un total de 472 pacientes presentaron fracturas mandibulares, de los cuales 54 pacientes (11,4% desarrollaron alguna complicación postoperatoria al tratamiento. En el grupo de pacientes con complicaciones postoperatorias, el género masculino predominó con 44 pacientes y la media de edad fue de 29,3 años de edad. En este grupo se presentaron sin actividad económica 35,2% de los pacientes y 33 (61% relataron abuso en sustancias nocivas a la salud. La agresión física fue la causa mas común (35,1%. Fracturas mandibulares múltiples fueron relatadas en 34 pacientes (62,9%. Infección se presento en 32 pacientes (59,2%. Tratamiento hospitalario para las complicaciones fue necesario para 30 pacientes (55,5%. Conclusiones: Actividad económica y demora en el tratamiento de fracturas mandibulares no fueron significantes en el desarrollo de complicaciones post-operatorias. Por otra parte, la severidad del trauma y el tipo de fractura, consideradamente pueden influir, así como el consumo de sustancias, que presentó una fuerte relación en la presencia de complicaciones.Objective: This study was made to determine the factors relevant to postoperative complications in patients treated for mandibular fracture. Study design: The study was based on the medical

  19. Important factors for BPR success in manufacturing firms Fatores relevantes para o êxito de reengenharia de processos em empresas de manufatura

    Directory of Open Access Journals (Sweden)

    Tor Guimaraes

    1998-04-01

    aqui definido em três diferentes aspectos: metas e objetivos do projeto, benefícios obtidos do projeto, e o impacto no desempenho da empresa. A partir dos resultados da pesquisa, são apresentadas recomendações para que os gerentes foquem sua atenção e recursos nos fatores relevantes ao êxito e procedam de forma a minimizar o risco de fracasso. Questionários foram enviados pelo correio a gerentes e diretores de auditoria interna de 586 empresas de manufatura selecionadas aleatoriamente. Obteve-se uma amostra de 135 questionários, representando uma taxa de resposta de 22 por cento. De modo geral, as empresas não estão enfatizando algumas das mais importantes atividades e tarefas recomendadas na literatura de reengenharia, tais como mudança para processos de negócio orientados para o mercado, o elemento que adiciona valor a cada atividade de negócios e aplicação da inovação tecnológica adequada. Baseado nos resultados, recomenda-se à alta administração que não se engaje em projetos de reengenharia antes de ter assegurado a presença dos fatores de êxito considerados relevantes na pesquisa. Embora os resultados sejam baseados em empresas de manufatura, os mesmos podem ser generalizados para outros setores.

  20. Major congenital defects. Relevant risk factors. Cienfuegos. 2000-2005. Malformaciones congénitas mayores. Factores de riesgo relevantes. Cienfuegos. 2000-2005.

    Directory of Open Access Journals (Sweden)

    Gladis Barberis Pérez

    2008-04-01

    Full Text Available

    Background: Major congenital defects have an impact on perinatal mortality and morbidity with economic and social consequences. Objective: To determine the relevant risk factors linked to the occurrence of congenital defects in Cienfuegos between 2000 and 2005. Methods: A case-control study was carried out. Women with fetus or newborns with major congenital defects formed the case group (255 while the control group consisted of a similar number of healthy children selected each year by a randomized simple sample. The variables gathered by the Cuban Congenital Defects Records were studied. Chi-Square method was used with 95% of accuracy and a reliance rate of 95%; logistic regression was used with the Wald test. Results: There was a predominance of Central Nervous System defects (28, 6%. The most relevant risk factors were a history of congenital defects, smoking habits, and acute infection during the first three months, as well as belong to the third birth on. Conclusion: The most clinical relevant risks factors were the congenital defect history and the acute infection during the firs three months.

    Fundamento: Las malformaciones congénitas mayores influyen en la morbimortalidad perinatal, lo que tiene implicaciones sociales y económicas. Objetivo: Determinar los factores de riesgo relevantes, asociados a la aparición de malformaciones congénitas mayores, en la provincia Cienfuegos en el período 2000-2005. Métodos: Se realizó un estudio de casos y controles no pareados. Las mujeres registradas con fetos o recién nacidos con malformaciones congénitas mayores, constituyeron el grupo de casos (255, mientras que el grupo control estuvo conformado por un número similar de niños sanos, seleccionados en cada año, por un muestreo aleatorio simple. Se estudiaron las variables recogidas en el modelo

  1. Aspectos Relevantes Acerca de la Producción de Maíz y Trigo Bajo la Perspectiva de Datos en Painel

    Directory of Open Access Journals (Sweden)

    Dilamar Dallemole

    2014-11-01

    Full Text Available O comércio internacional de commodities tem intensificado um processo de significativas transformações no setor agropecuário, base das principais cadeias agroalimentares, nas mais variadas regiões. Regulamentações supranacionais acabam por ser incorporadas ao processo produtivo que, associadas ao aumento na demanda por alimentos, intensificam as exigências e pressionam a produção no campo. Envolto a tais condicionantes, os mercados de milho e trigo ajustam-se e evoluem de acordo com estes novos paradigmas e, por serem responsáveis por expressivos impactos socioeconômicos, torna-se oportuno identificar aspectos relevantes acerca da produção e compreender a dinâmica de suas relações. Sob essa perspectiva, o horizonte volta-se para a determinação dos condicionantes da produção de milho e trigo, por meio da identificação das categorias de maior influência. Empregou-se o modelo analítico de Dados em Painel, no sentido de mensurar quais categorias são responsáveis pelas alterações na oferta, com as devidas correlações e tendências. Os resultados apontam para a necessidade de políticas moderadas de ajuste de câmbio, incentivo às exportações e ao consumo, pois tratam-se dos fatores mais importantes no que se refere a impactos sobre a produção nestes mercados.

  2. From BASIS to MIRACLES

    DEFF Research Database (Denmark)

    Tsapatsaris, Nikolaos; Willendrup, Peter Kjær; E. Lechner, Ruep;

    2015-01-01

    Results based on virtual instrument models for the first high-flux, high-resolution, spallation based, backscattering spectrometer, BASIS are presented in this paper. These were verified using the Monte Carlo instrument simulation packages McStas and VITESS. Excellent agreement of the neutron cou...... are pivotal to the conceptual design of the next generation backscattering spectrometer, MIRACLES at the European Spallation Source....

  3. PERCEPÇÃO DOS GRADUANDOS EM CIÊNCIAS CONTÁBEIS DE SALVADOR (BA SOBRE OS CONCEITOS RELEVANTES DA TEORIA DA CONTABILIDADE

    Directory of Open Access Journals (Sweden)

    Adriano Leal Bruni

    2012-06-01

    Full Text Available Um domínio apropriado dos conceitos básicos da Contabilidade e uma análise das suas características são essenciais para o desenvolvimento da Teoria Contábil. O processo de tomada de decisões financeiras exige o conhecimento de valores econômicos adequados, o que se torna cada vez mais demandado pelos usuários da Contabilidade. Este trabalho, portanto, buscou aferir a compreensão de alguns termos explorados no contexto da disciplina Teoria da Contabilidade, tais como ativos, passivos, goodwill, receitas, despesas, ganhos e perdas. Examinou-se uma amostra composta por 591 alunos matriculados em cursos de Ciências Contábeis que já haviam frequentado a disciplina Teoria da Contabilidade em instituições de ensino superior localizadas na cidade de Salvador (BA. A análise dos resultados por meio de uma regressão logística indica que a relação desempenho do discente e titulação do docente é mais significativa que a relação desempenho do discente e tipo da IES, contudo, de forma geral, conceitos superficiais sobre os tópicos tratados nesse trabalho foram citados em todos os níveis. Os resultados evidenciaram, em geral, falhas na compreensão de conceitos contábeis relevantes para a formação do aluno, refletindo majoritariamente uma visão superada ou, no mínimo, conservadora. Quando comparados por tipo de instituição de ensino, os resultados indicam que estudantes de instituições públicas possuem melhor domínio dos conceitos considerados neste estudo. A compreensão melhora um pouco mais quando a titulação do docente evolui de especialista para mestre e deste para doutor.

  4. EXPLICAR LA CALIDAD DEMOCRÁTICA: ¿QUÉ TAN RELEVANTES SON LAS TRADICIONES AUTORITARIAS? Explaining Democratic Quality: How Relevant is the Authoritarian Legacy?

    Directory of Open Access Journals (Sweden)

    Leonardo Morlino

    2007-01-01

    Full Text Available Esta es una versión revisada de la lectura abierta dada por el autor el año 2004, en la conferencia de la sociedad italiana de Ciencia política en Padua. En la primera sección se discute la principal definición de democracia y calidad democrática, como estado de derecho, accountability electoral, accountability interins titucional, responsiveness, libertad y equidad/solidaridad. En la segunda parte surge una pregunta clave: si nosotros quisiéramos explicar la calidad de la democracia, ¿cuán relevantes son las tradiciones políticas previas? también son sugeridos otros factores explicativos que complementan el rol de los legados autoritarios, proponiendo pequeñas hipótesis clave. En la última sección se analiza el impacto del legado autoritario sobre la calidad de las democracias contemporáneas en países del sur de Europa como Portugal, España e Italia y el Cono Sur de Latinoamérica tal como Chile, Argentina, Uruguay y BrasilThis is the revised draft ofthe opening lecture given by the author atthe 2004 Conference of Italian Society of Political Science in Padua. Inthe first sectionthe main definitions of democracy and democratic qualities rule of law, electoral accountability, inter-ins titutional accountability, responsiveness, freedom and equality/solidarity are discussed. Inthe second a key ques tion is addressed: if we would liketo explainthe qualities of a democracy how much arethe previous politicaltraditions ofthe country relevant? Other explanatory factors, which complementthe role of an authoritarian legacy, are also sugges ted and a few key hypotheses are proposed.the final section does not provide any comprehensive explanation, but analyses ofthe impact of authoritarian legacy in a few countries of Southern Europe, such as Portugal, Spain, and Italy (but not Greece where it is not relevant and inthe Southern Cone as Chile, Argentina, Uruguay, Brazil, wherethe quality of contemporary democracies is ques tioned

  5. ASPECTOS RELEVANTES DA APROXIMAÇÃO ENTRE BRASIL E CHINA: UMA ABORDAGEM ANALÍTICA [doi: 10.5329/RECADM.20050401009

    Directory of Open Access Journals (Sweden)

    Silvio Aparecido Crepaldi

    2005-05-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE MicrosoftInternetExplorer4 RESUMO Nos últimos anos, cresceu notavelmente o interesse mútuo entre o Brasil e a China. Na década de 1990 ambos os países se esforçaram para promover a multi-polarização do poder mundial e fortalecer a cooperação entre países em desenvolvimento. Brasil e China trabalham com vistas à consolidação de uma parceria estratégica, o que tem impulsionado as relações bilaterais; mas há ainda desafios a serem superados. Com esta realidade surge uma lacuna na bibliografia sobre os aspectos relevantes da aproximação Brasil e China. Assim, a carência de bibliografias voltadas ao assunto que incluam o estudo desta aproximação e seus reflexos, motiva à pesquisa visando sanar essas deficiências. Pretende-se analisar as relações comerciais sino-brasileiras de 1984 a 2002 e explorar o significado do conceito de parceria estratégica no relacionamento dos dois países. Antes disso, contudo, são indispensáveis algumas ponderações extraídas da sua análise global, permitindo a melhor reflexão e apontamento de conclusões sobre as relevantes matérias tratadas na referida aproximação Brasil e China. Em conseqüência do cenário exposto, a problemática pode ser sintetizada na seguinte questão: "como Brasil e China deveriam interagir entre si para obter uma inserção mutuamente vantajosa no mundo globalizado?". As informações referentes ao tema aproximação entre Brasil e China foram obtidas mediante pesquisa bibliográfica. O volume das transações comerciais entre Brasil e China vem evoluindo rapidamente e a China tornou-se recentemente o maior parceiro comercial do Brasil na Ásia. Há ainda enormes potencialidades comerciais a serem exploradas. Ao mesmo tempo, a economia chinesa consegue gerar empregos urbanos em escala astronômica. Somente nos primeiros 9 (nove meses deste ano, foram criados cerca de 8 milhões de postos de trabalho nas cidades

  6. Aspectos relevantes no diagnóstico de dort e fibromialgia Important aspects of diagnosing work-related musculoskeletal disorders (WMSD and fibromyalgia

    Directory of Open Access Journals (Sweden)

    JF Alencar

    2009-02-01

    Full Text Available CONTEXTUALIZAÇÃO: A dor crônica e difusa encontra-se presente tanto nas Lesões por Esforços Repetitivos (LER/Distúrbios Osteomusculares Relacionados ao Trabalho (DORT como na Fibromialgia, trazendo dificuldades diagnósticas, preventivas e terapêuticas para profissionais da saúde envolvidos no tratamento de acometidos. OBJETIVOS: Analisar os aspectos relevantes na emissão dos diagnósticos de DORT e Fibromialgia na percepção de médicos assistenciais e peritos. MÉTODOS: Neste estudo, 75 médicos (36 assistenciais e 39 peritos responderam a questões estruturadas e abertas sobre aspectos considerados relevantes na emissão de diagnóstico destas síndromes. RESULTADOS: As respostas dos dois grupos foram correlacionadas pelo teste de Spearman (α=0,05 e submetidos ao método de Discurso do Sujeito Coletivo (DSC. Os médicos assistenciais tenderam a valorizar o fator "quadro clínico e tempo de evolução", enquanto os médicos peritos tenderam a apontar "história ocupacional" na definição do diagnóstico de LER/DORT. Já para o diagnóstico de Fibromialgia, os peritos tenderam a apontar o fator "quantidade de tender points", enquanto os médicos assistenciais indicaram mais frequentemente "característica da dor". Apesar dessas discretas discrepâncias, alta correlação (r=0,85, ρ=0,01 foi identificada entre os grupos quando apontaram aspectos comuns e distintos no estabelecimento do diagnóstico para as duas síndromes. Os relatos também enfatizaram a necessidade da investigação de riscos presentes no trabalho para a definição de um diagnóstico mais preciso. CONCLUSÕES: Nesse sentido, objetivando uniformizar condutas avaliativas, preventivas e terapêuticas para médicos, fisioterapeutas e demais profissionais envolvidos no atendimento dessas síndromes, seria recomendável maior divulgação dos critérios utilizados por entidades internacionais no diagnóstico da Fibromialgia e a inclusão de treinamento para identifica

  7. Design basis 2

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, G.; Soerensen, P. [Risoe National Lab., Roskilde (Denmark)

    1996-09-01

    Design Basis Program 2 (DBP2) is comprehensive fully coupled code which has the capability to operate in the time domain as well as in the frequency domain. The code was developed during the period 1991-93 and succeed Design Basis 1, which is a one-blade model presuming stiff tower, transmission system and hub. The package is designed for use on a personal computer and offers a user-friendly environment based on menu-driven editing and control facilities, and with graphics used extensively for the data presentation. Moreover in-data as well as results are dumped on files in Ascii-format. The input data is organized in a in-data base with a structure that easily allows for arbitrary combinations of defined structural components and load cases. (au)

  8. Competências e habilidades relevantes para um chefe de unidade descentralizada de perícia da polícia federal.

    Directory of Open Access Journals (Sweden)

    Odair de Souza Gloria Junior

    2014-08-01

    Full Text Available Esta pesquisa teve por objetivo descrever as competências técnicas e habilidades necessárias para um perito criminal federal no exercício da função de chefe de unidade de perícia da Polícia Federal, especificamente nos setores técnico-científicos (Setecs e nas unidades técnico-científicas (Utecs, segundo a teoria de competências e habilidades. A releitura desses fundamentos, incluindo habilidades sociais nesse escopo, fortaleceu o embasamento teórico para análise dos resultados da etapa empírica desta pesquisa. Essa postura pode contribuir, na prática, para a construção de uma política de gestão de pessoas, baseada em competências, alinhada com o planejamento estratégico em desenvolvimento na organização, otimizando a designação para os cargos de liderança, sobretudo na área de criminalística, considerando as especificidades da área de atuação. Foi aplicado um questionário com dez questões sobre a atuação profissional e informações sociodemográficas, além de um inventário em que os respondentes indicavam a importância e o grau de domínio de uma série de competências selecionadas por meio de análise da literatura. Após a devida aprovação, o questionário foi enviado para todos os 53 chefes de unidades de perícia da Polícia Federal. Os resultados indicam diferenças no que tange ao domínio de competências entre os chefes da Utec, mais jovens e com menor tempo de experiência, e o grupo de chefes do Setec, com maior tempo de atuação na perícia e também em gestão. Os resultados ainda permitiram destacar algumas competências técnicas e habilidades mais relevantes que deverão ser desenvolvidas para e pelos peritos que exercem a função de chefia em unidade de perícia da Polícia Federal ou aspiram a ela. Os resultados permitiram também uma melhor compreensão das relações entre competências e habilidades, e, na prática, auxiliaram a esclarecer o panorama de avanços e limitações na

  9. Expression, Reinigung und biophysikalische Charakterisierung verschiedener Hydrolasen des Sphingolipid-Stoffwechsels

    OpenAIRE

    Ficht-Redmer, Susanne

    2015-01-01

    Sphingolipide sind eine wichtige Klasse von Lipiden, die nicht nur als Strukturmoleküle von Bedeutung sind sondern auch in Signaltransduktionsprozessen eine wichtige Rolle spielen. Insbesondere die Sphingolipidmetaboliten Ceramid, Sphingosin und Sphingosin-1-phosphat sind an zellulären Prozessen wie Differenzierung, Apoptose, Proliferation und Inflammation beteiligt. Sphingomyelinasen üben daher als katabole Enzyme des Sphingolipidstoffwechsels eine wichtige Funktion aus. Die vorliegende Ar...

  10. Laser therapy of the lung: biophysical background; Lasertherapie in der Lunge: Biophysikalischer Hintergrund

    Energy Technology Data Exchange (ETDEWEB)

    Knappe, V. [Laser- und Medizin-Technologie GmbH Berlin, Berlin (Germany); Mols, A. [Campus Benjamin Franklin, Charite - Universitaetsmedizin Berlin (Germany)

    2004-07-01

    The laser is a well established surgical instrument in lung therapy. This report provides information on the biophysical basics of the laser-induced thermotherapy (LITT) of lung metastases. Optical properties like absorption and scattering determine the penetration depth of laser radiation in tissue. These parameters vary dynamically during the application and define in combination with thermal tissue properties the achievable destruction volume. Parenchyma behaves very differently compared to more dense tissues due to local inhomogenities and the large amount cavaties filled with air. Beside an account of the affecting parameters an overview of therapy options is given. Therapeutic results depend not only on the tissue properties but also on the technical equipment, e.g. the applicator design and the energy applied. Complex dosimetric models allow for a calculation of the lesion's size in advance. (orig.) [German] Der Laser ist in der Lungenchirurgie ein bereits etabliertes Instrument. In diesem Beitrag werden speziell die biophysikalischen Hintergruende der laserinduzierten Thermotherapie (LITT) von Lungenmetastasen beschrieben. In der Gewebeoptik determinieren Absorption und Streuung die Eindringtiefe von Laserlicht. Diese Parameter veraendern sich dynamisch waehrend der Anwendung und bestimmen in Verbindung mit den thermischen Gewebeeigenschaften die maximal erzielbaren Destruktionsvolumina. Lokale Inhomogenitaeten und der hohe Anteil luftgefuellter Hohlraeume unterscheiden das Parenchym in dieser Hinsicht signifikant von dichteren Geweben. Neben einer Darstellung der beeinflussenden Parameter wird ein Ueberblick ueber die Therapieoptionen gegeben. Der Therapieerfolg haengt neben den genannten gewebeseitigen Parametern von Anzahl und Geometrie der Applikatoren und der applizierten Energie ab und kann mit komplexen Dosimetriemodellen im voraus kalkuliert werden. (orig.)

  11. ITER technical basis

    International Nuclear Information System (INIS)

    Following on from the Final Report of the EDA(DS/21), and the summary of the ITER Final Design report(DS/22), the technical basis gives further details of the design of ITER. It is in two parts. The first, the Plant Design specification, summarises the main constraints on the plant design and operation from the viewpoint of engineering and physics assumptions, compliance with safety regulations, and siting requirements and assumptions. The second, the Plant Description Document, describes the physics performance and engineering characteristics of the plant design, illustrates the potential operational consequences foe the locality of a generic site, gives the construction, commissioning, exploitation and decommissioning schedule, and reports the estimated lifetime costing based on data from the industry of the EDA parties

  12. Un método para la educción de requisitos a partir de extracción de información relevante de vídeos documentales

    OpenAIRE

    Maturana González, Grissa Vianney

    2015-01-01

    Resumen : La educción de requisitos comprende, principalmente, la captura y descubrimiento de la información relevante para la conformación de los requisitos del software, por medio de técnicas como entrevistas, cuestionarios y videos, entre otras. Algunos autores plantean el uso de videos para validar los requisitos de un sistema y para visualizar múltiples escenarios de las actividades que realizan los interesados. Otros autores buscan indexar y extraer información automáticamente de los vi...

  13. Características relevantes nos grupos de trabalho - Caso das Equipas de Intervenção Rápida na Polícia de Segurança Pública

    OpenAIRE

    Pedro, Ricardo Pedrosa

    2010-01-01

    Mestrado em Gestão de Recursos Humanos A melhoria do desenvolvimento dos grupos de trabalho assenta na necessidade de se conhecerem as suas principais características. A percepção dos elementos é reflexo do desempenho do grupo na organização. Conhecer a percepção que esses elementos têm das características mais importantes no grupo faculta assim, o diagnóstico para se elevar o desempenho do grupo. O estudo tem por objectivo identificar as características mais relevantes em Equipas de Inter...

  14. Transparent reporting of studies relevant to physical therapy practice Como escrever de forma transparente artigos científicos relevantes para a prática da Fisioterapia

    Directory of Open Access Journals (Sweden)

    Leonardo O. P. Costa

    2011-08-01

    Full Text Available BACKGROUND: There was a clear grow, in the last 2 decades, of up to 6 fold in scientific articles that are directly relevant to physical therapy practice. However, along with this fast grow; little attention has been given to transparency when reporting research methods and results. More recently, groups of researchers around the world have made successful attempts to address this issue by creating guidelines that will help researchers not only on the preparation of manuscripts but also on making sure that important details related to design and methodology are controlled and reported. OBJECTIVE: To present four specific reporting guidelines, which are best known as "statements". DISCUSSION: A network named EQUATOR (Enhancing the Quality and Transparency of Health Research was created with the main mission of providing basic principles for responsible and transparent reporting. The EQUATOR network encompasses, among others, the CONSORT statement which is related to randomized controlled trials; the PRISMA statement, which is related to systematic reviews and meta-analysis; the STROBE Statement, which is related to observational studies; and the STARD statement, which is related to reporting of accuracy of diagnostic tests. Some journals have recommended the use of these statements, while in others their use is mandatory. The goal of the use of these statements by journals is to guarantee fast decisions regarding publication and the best possible quality of reporting. Ultimately, it will help readers, including physical therapists, to make better decisions in clinical practice.CONTEXTUALIZAÇÃO: Nas últimas duas décadas, ocorreu um nítido crescimento, de até seis vezes, do número de artigos científicos que são diretamente relevantes para a prática da Fisioterapia. No entanto, junto com esse rápido crescimento, tem-se dado pouca atenção à transparência de como são descritos os métodos e os resultados desses estudos. Mais

  15. Expert`s discourse: methods and results on resorptional availability of relevant pollutants in contaminated soil and other material; Methoden und Ergebnisse zur Resorptionsverfuegbarkeit relevanter Schadstoffe in kontaminierten Boeden und Materialien

    Energy Technology Data Exchange (ETDEWEB)

    Barkowski, D.; Guenther, P.; Krause, H.; Machtolf, M.

    1999-01-01

    The requirements in the Federal Soil Protection Law (Bundes-Bodenschutzgesetz) ask for more concrete forms of a legal decree on a sub-legal level concerning the judgement of risk evaluation of existing soil alterations. Among other items this would provide for the establishment of trigger and measure values, even if trigger values have already been proposed for priority substances, the discussion on the derivation of measure values - here concerning the direct pathway - has not come to an end yet. Especially it is still being criticized how far methodical basics would be yet available in order to identify the amount of human-toxicological material in the soil. In order to summarize the latest scientific findings, main topics of the experts` discourse on this research project were methods and results on resorptional availability of relevant pollutants in contaminated soil and other material. Preparing this discourse the experts were systematically questioned by a special inquiry form. Additionally to this, a short essay was provided for them, which made the momentary status quo available to the participants in order to be prepared for the experts` discourse. The guided experts` discourse took place on 10th February 1998 and dealed with those procedures methodically established and developed in Germany (Stomach-Intestine-Model of the Ruhr-Universitaet Bochum, Salive-Stomach-Intestine-Model of the Umweltbundesamt as well as the DIN/EN 71,3, which is being in use within the administrational execution in Baden-Wuerttemberg). In addition specifications regarding validation and further development as well as possibilities were discussed by means of how far a standardisation of the procedure for collecting data on the availability of resorption of contaminants would seem promising. Thus it could be outlined that on the basis of research and developmental projects of the recent years a state of methods has already been reached, which - including several detail-works to be

  16. La irrupción del imaginario social, las subjetividades y los sujetos en las ciencias sociales como asunto relevante para la investigación en educación

    Directory of Open Access Journals (Sweden)

    Claudia Patricia Sierra

    2015-12-01

    Full Text Available Distintas disciplinas han cuestionado la dicotomía de la ciencia moderna entre mundo objetivo y mundo subjetivo. Autores como Durand, Bachelard, Cassirer, Castoriadis, Zemelman, Wunenburger, Ibáñez, entre otros, complejizaron el análisis del sujeto “racional” moderno y del sujeto “histórico” marxista, revalorando lo simbólico y la construcción de significaciones sobre la realidad como asuntos relevantes para comprender las dinámicas sociales. Sus cuestionamientos han permitido el surgimiento de miradas más complejas e investigaciones ancladas en otros horizontes. Este artículo hace énfasis en la importancia de lo imaginario para las ciencias sociales, particularmente en su relación con la constitución de subjetividades y sujetos, planteando posibles rastreos del tema en prácticas educativas populares.

  17. Flavor Democracy: On which basis?

    CERN Document Server

    Rador, T

    2003-01-01

    I argue that flavor democracy should not be considered as a "mere" assumption, but rather a fact that is inherent where there is hierarchy of quark masses. Briefly the crux of the argument is the ambiguity of defining a basis when one introduces a mass matrix. That is there is a degree of freedom of also defining a basis other than the weak eigenbasis with respect to which one can write down mass matrices. Since the ultimate aim is to diagonalize to the mass eigenbasis this is physically equivalent. But not necessarily so for the human eye.

  18. An overview of research designs relevant to nursing: Part 3: Mixed and multiple methods Revisión de los diseños de investigación relevantes para la enfermería: Parte 3: Métodos mixtos y múltiples Revisão dos desenhos de pesquisa relevantes para enfermagem: Parte 3: Métodos mistos e múltiplos

    Directory of Open Access Journals (Sweden)

    Driessnack Martha

    2007-10-01

    Full Text Available This third article of the series "An Overview of Research Designs Relevant to Nursing" presents the use of mixed or multiple methods in nursing research. The use of mixed or multiple methods is a growing trend that offers another option for researchers in addressing the complex health problems faced in nursing today. Understanding of all methods and all combinations of methods facilitate the conduction and dissemination of research to serve nursing practice.Este tercero artículo de la serie "Revisión de los Diseños de Investigación Relevantes para la Enfermería" presenta el uso de los métodos mixtos o múltiples en la investigación en enfermería. El uso de métodos mixtos o múltiples es una tendencia creciente que ofrece una alternativa a los investigadores en la aproximación de problemas complejos de la salud enfrentados actualmente en la enfermería. Entender todos los métodos y todas las combinaciones de métodos facilita la conducción y diseminación de la investigación para servir a la práctica de la enfermería.Este terceiro artigo da série "Revisão dos Desenhos de Pesquisa Relevantes para Enfermagem" apresenta o uso dos métodos mistos ou múltiplos na pesquisa em enfermagem. O uso de métodos mistos ou múltiplos é uma tendência crescente que oferece uma alternativa aos pesquisadores na abordagem de problemas complexos da saúde enfrentados atualmente em enfermagem. Entender todos os métodos e todas as combinações de métodos facilita a condução e disseminação da pesquisa para servir a prática da enfermagem.

  19. Temas ambientais relevantes Relevant environmental issues

    Directory of Open Access Journals (Sweden)

    Eneas Salati

    2006-04-01

    Full Text Available NESTE trabalho, são indicados os principais temas ambientais para o Brasil, num futuro próximo (2022. Impactos do aumento da temperatura são estudados através de cenários, que podem modificar o balanço hídrico em algumas regiões, tendo sido observado um aumento da ordem de 0,78ºC no período de 1917 a 2003, na região de Piracicaba. Para a região amazônica, foi observado um aumento de 0,56ºC durante o século XX. Tanto o desmatamento quanto as Mudanças Climáticas Globais atuam na direção de um aumento da temperatura, enquanto o desmatamento influi na direção de uma diminuição das precipitações. O desmatamento provoca, ainda, uma grande perda de biodiversidade, sendo estimadas em uma perda entre 8.000 até 34.000 espécies, considerando-se que o desmatamento aumenta em 1% ao ano.THIS PAPER indicates the environmental issues that must necessarily be approached, in Brazil, in a near future (2022. A study was made on some aspects of the effects of deforestation and Global Climate Change. A temperature rise around 0,78% has been observed during period of 1917 and 2003 in the Piracicaba region. For the Amazon region a rise of 0,56% was observed the 20th Century. The existing information indicates that not only deforestation but also Global Climate Changes act upon temperature rise. Deforestation has direct influence in precipitation decrease. The consequences of Global Climate Change are still unknown, being that some models indicate a precipitation rise and others a decrease. Deforestation also provokes great biodiversity loss, estimated between 8.000 to 34.000 species, considering that deforestation raises 1% per year.

  20. Genetic basis of chronic pancreatitis

    NARCIS (Netherlands)

    Jansen, JBMJ; Morsche, RT; van Goor, Harry; Drenth, JPH

    2002-01-01

    Background: Pancreatitis has a proven genetic basis in a minority of patients. Methods: Review of the literature on genetics of pancreatitis. Results: Ever since the discovery that in most patients with hereditary pancreatitis a mutation in the gene encoding for cationic trypsinogen (R122H) was foun

  1. GASB's Basis of Accounting Project.

    Science.gov (United States)

    Kovlak, Daniel L.

    1986-01-01

    In July 1984, the Governmental Accounting Standards Board began its "Measurement Focus/Basis of Accounting" project, which addresses measurement issues and revenue and expenditure recognition problems involving governmental funds. This article explains the project's background, alternatives discussed by the board, and tentative conclusions and…

  2. Thermodynamic basis for cluster kinetics

    DEFF Research Database (Denmark)

    Hu, Lina; Bian, Xiufang; Qin, Xubo;

    2006-01-01

    Due to the inaccessibility of the supercooled region of marginal metallic glasses (MMGs) within the experimental time window, we study the cluster kinetics above the liquidus temperature, Tl, to acquire information on the fragility of the MMG systems. Thermodynamic basis for the stability...

  3. Authorization basis requirements comparison report

    Energy Technology Data Exchange (ETDEWEB)

    Brantley, W.M.

    1997-08-18

    The TWRS Authorization Basis (AB) consists of a set of documents identified by TWRS management with the concurrence of DOE-RL. Upon implementation of the TWRS Basis for Interim Operation (BIO) and Technical Safety Requirements (TSRs), the AB list will be revised to include the BIO and TSRs. Some documents that currently form part of the AB will be removed from the list. This SD identifies each - requirement from those documents, and recommends a disposition for each to ensure that necessary requirements are retained when the AB is revised to incorporate the BIO and TSRs. This SD also identifies documents that will remain part of the AB after the BIO and TSRs are implemented. This document does not change the AB, but provides guidance for the preparation of change documentation.

  4. Perceptual basis for reactive teleoperation.

    Energy Technology Data Exchange (ETDEWEB)

    Park, Y. S.; Ewing, T. F.; Boyle, J. M.; Yule, T. J.

    2001-08-28

    To enhance task performance in partially structured environment, enhancement of teleoperation was proposed by introducing autonomous behaviors. Such autonomy is implemented based on reactive robotic architecture, where reactive motor agents that directly couples sensory inputs and motor actions become the building blocks. To this end, presented in this paper is a perceptual basis for the motor agents. The perceptual basis consists of perceptual agents that extracts environmental information from a structured light vision system and provide action oriented perception for the corresponding motor agents. Rather than performing general scene reconstruction, a perceptual agent directly provides the motion reference for the motor behavior. Various sensory mechanisms--sensor fission, fusion, and fashion--becomes basic building blocks of the perception process. Since perception is a process deeply intertwined with the motor actions, active perception may also incorporate motor behaviors as an integral perceptual process.

  5. Hanford Generic Interim Safety Basis

    International Nuclear Information System (INIS)

    The purpose of this document is to identify WHC programs and requirements that are an integral part of the authorization basis for nuclear facilities that are generic to all WHC-managed facilities. The purpose of these programs is to implement the DOE Orders, as WHC becomes contractually obligated to implement them. The Hanford Generic ISB focuses on the institutional controls and safety requirements identified in DOE Order 5480.23, Nuclear Safety Analysis Reports

  6. Hanford Generic Interim Safety Basis

    Energy Technology Data Exchange (ETDEWEB)

    Lavender, J.C.

    1994-09-09

    The purpose of this document is to identify WHC programs and requirements that are an integral part of the authorization basis for nuclear facilities that are generic to all WHC-managed facilities. The purpose of these programs is to implement the DOE Orders, as WHC becomes contractually obligated to implement them. The Hanford Generic ISB focuses on the institutional controls and safety requirements identified in DOE Order 5480.23, Nuclear Safety Analysis Reports.

  7. Penentuan Basis bagi Graf Roda

    OpenAIRE

    Ulfah Dwiyanti Obed, Nur

    2015-01-01

    Misalkan G=(V,E) suatu graf terhubung dan S adalah suatu himpunan bagian dari V. Himpunan S disebut himpunan penentu (resolving set) pada G jika untuk setiap titik pada G memiliki representasi jarak yang berbeda terhadap S. Himpunan penentu dengan banyak anggota (kardinalitas) minimum disebut himpunan penentu minimum (resolving set minimum) atau basis dari G dan kardinalitas himpunan tersebut menyatakan dimensi metrik (metric dimension) graf G, dinotasikan dengan dim(G). Pada skripsi ini t...

  8. Theoretical basis of alveolar sampling.

    OpenAIRE

    Kelman, G R

    1982-01-01

    The conditions under which the partial pressure of a solvent in the alveolar gas is likely to provide a valid index of its partial pressure in the mixed venous blood, and thus of whole-body exposure, is explored on a theoretical basis. Under steady-state conditions, providing the solvent's blood/gas partition coefficient exceeds 10, its mixed venous and alveolar pressures will agree within 10% and become virtually identical during the prolonged expiration necessary to obtain an alveolar sampl...

  9. A physical basis for MOND

    OpenAIRE

    Macleod, Alasdair

    2007-01-01

    MOND is a phenomenological theory with no apparent physical justification which seems to undermine some of the basic principles that underpin established theoretical physics. It is nevertheless remarkably successful over its sphere of application and this suggests MOND may have some physical basis. It is shown here that two simple axioms pertaining to fundamental principles will reproduce the characteristic behaviour of MOND, though the axioms are in conflict with general relativistic cosmology.

  10. Common basis for cellular motility

    OpenAIRE

    Zot, Henry G.; Javier E Hasbun; Minh, Nguyen Van

    2015-01-01

    Motility is characteristic of life, but a common basis for movement has remained to be identified. Diverse systems in motion shift between two states depending on interactions that turnover at the rate of an applied cycle of force. Although one phase of the force cycle terminates the decay of the most recent state, continuation of the cycle of force regenerates the original decay process in a recursive cycle. By completing a cycle, kinetic energy is transformed into probability of sustaining ...

  11. Fatores relevantes para aquisição da coda lexical e morfológica no português brasileiro Factors relevant for acquisition of lexical and morphological coda in Brazilian portuguese

    Directory of Open Access Journals (Sweden)

    Carolina Lisbôa Mezzomo

    2010-06-01

    Full Text Available OBJETIVO: analisar as variáveis relevantes na aquisição das codas, morfológica (ex. cadeiras e lexical (ex. lápis, quando preenchidas pela fricativa /S/ em final de palavra. MÉTODOS: verificaram-se os dados de fala de 15 crianças, 10 meninas e 5 meninos, entre 1:7 e 3:7, falantes monolíngues do português brasileiro, gravados quinzenalmente por um período de um ano. Os dados de fala foram obtidos por meio de atividades lúdicas, transcritos e revistos. Estes foram submetidos à análise estatística através do uso do Pacote Computacional VARBRUL. RESULTADOS: o programa selecionou, para ambas as codas as variáveis, classe gramatical e sexo, como relevantes a produção correta. Dentre as classes gramaticais, pronomes e advérbios, foram apontados como favorecedores à produção correta para os dois tipos de coda. Somado a essas, o programa selecionou também para coda lexical a classe dos substantivos, e para coda morfológica a classe dos numerais. As variáveis, tonicidade e contexto precedente mostraram-se favorecedoras da produção das codas lexicais, com maior probabilidade de realização correta quando há uma sílaba tônica e o contexto precedente for composto por vogal dorsal. A idade foi considerada uma variável favorecedora na produção da coda morfológica, com resultado estaticamente significante nas crianças mais velhas. CONCLUSÃO: observou-se que a classe gramatical e o sexo são importantes no domínio de ambos os tipos de coda, no entanto, o processo de domínio de /S/ nos dois casos mostrou variáveis distintas, podendo-se inferir que a criança as trata de maneira singular no seu processo de aquisição.PURPOSE: to analyze the relevant variables in the acquisition of morphological (e.g. cadeiras and lexical (e.g. lápis codas, with the fricative /S/ at the end of the word. METHODS: we examined data from 15 children, 10 girls and 5 boys, aged between 1:7 and 3:7, monolingual speakers of Brazilian Portuguese

  12. Informational Competence: A Relevant Conception to Take into Consideration in Higher Education La competencia informacional: concepción relevante a considerar en la Educación Superior

    Directory of Open Access Journals (Sweden)

    María Elinor Dulzaides Iglesias

    Full Text Available Competence is today a relevant conception to take into consideration. It implies more integration between strategy, study system, work and organizational culture, along with information management and knowledge. It offers potential to people and their development. The management of roles by competences is focused in development; it looks for what people are capable of doing in the future. Present day scenarios demand for a new educative arquitecture following learning for life, what implies: teaching to learn and, overall, to use information in an adequate manner. In this work we lay stress on the topic as an essential element to consider in Higher Medical Education, given the constant changes in medicine and the need for knowledge and skills for an adequate practice.
    La competencia informacional es hoy una concepción relevante a considerar; implica mayor integración entre estrategia, sistema de estudio, trabajo y cultura organizacional; junto al manejo de la información y el conocimiento proporciona potencialidad en las personas y su desarrollo. La gestión del desempeño por competencias se enfoca en esencia hacia el desarrollo, busca lo que las personas sean capaces de hacer en el futuro. Los escenarios actuales demandan una nueva arquitectura educativa que apunte al aprendizaje de por vida, lo que implica: enseñar a aprender y sobre todo utilizar adecuadamente la información. En este trabajo se enfatiza en el tema como elemento indispensable a considerar en la Educación Médica Superior, dado a los cambios constantes de la medicina y la necesidad de conocimientos y habilidades para una adecuada práctica.

  13. PERCEPCIÓN DEL RIESGO EN RELACIÓN CON CAPACIDADES DE AUTOPROTECCIÓN Y AUTOGESTIÓN, COMO ELEMENTOS RELEVANTES EN LA REDUCCIÓN DE LA VULNERABILIDAD EN LA CIUDAD DE LA SERENA

    Directory of Open Access Journals (Sweden)

    Carmen Paz Castro Correa

    2012-01-01

    Full Text Available Así como la concepción del riesgo y su terminología han variado en el tiempo, la perspectiva disciplinar de su abordaje también ha cambiado. Enfoques derivados de las ciencias naturales, aplicadas y sociales no permiten aún generar una teoría consistente y coherente del riesgo, difi cultando una gestión efectiva que facilite su estimación e intervención desde una perspectiva multidisciplinar. Asimismo, el riesgo no puede considerarse solamente de forma objetiva cuando se busca su reducción dada las múltiples interpretaciones y perspectivas de los distintos actores sociales que confl uyen. La percepción social del riesgo se presenta como uno de los factores relevantes en el ámbito de los riesgos naturales, pues permite incorporar estas subjetividades pudiendo encontrar soluciones más realistas a los desastres. El presente trabajo evalúa esta componente para la ciudad de La Serena, IV Región de Coquimbo, mediante su relación con el nivel socioeconómico, factores de autoprotección y capacidad de autogestión, respecto de la amenaza de tsunami propiciada por la sismicidad en un país como Chile, considerado mundialmente el más sísmico del mundo, al ubicarse en la zona de subducción y deslizamiento de las Placas de Nazca y Sudamericana. Se observa una clara segregación de los estratos socioeconómicos, en los distritos La Compañía Alta e Intendencia, encontrando zonas con mayor vulnerabilidad. Los resultados indican que la percepción de riesgo está relacionada con aspectos sociales, corroborando entonces el carácter social que posee el riesgo.

  14. O preparo da equipe cirúrgica: aspecto relevante no controle da contaminação ambiental La preparación del equipo quirúrgico: aspecto relevante en el control de la contaminación ambiental The preparation of the surgical team: significant aspect in the control of environmental contamination

    Directory of Open Access Journals (Sweden)

    Caroline Cataneo

    2004-04-01

    Full Text Available O controle da contaminação ambiental tem sido considerado como medida racional para a prevenção da infecção do sítio cirúrgico. O objetivo deste estudo é apresentar as atuais recomendações relacionadas ao preparo da equipe cirúrgica e tecer considerações sobre o papel do enfermeiro no controle da contaminação ambiental. Baseados na literatura atual, abordamos pontos relacionados à paramentação cirúrgica e a escovação das mãos. Os estudos apontam que o preparo da equipe cirúrgica constitui barreira de proteção importante para a prevenção da infecção do sítio cirúrgico; entretanto salientam a necessidade dos profissionais de saúde realizarem os procedimentos de forma adequada.El control de la contaminación ambiental ha sido considerado como una medida racional para la prevención de la infección en el sitio quirúrgico. El objetivo de este estudio es presentar las recomendaciones actuales con respecto a la preparación del equipo quirúrgico y hacer consideraciones acerca del papel del enfermero en el control de la contaminación ambiental. Basados en la literatura actual, tratamos puntos relacionados con el vestuario quirúrgico y al cepillado de las manos. Estudios indican que la preparación del equipo quirúrgico sirve como una importante barrera de protección en la prevención de la infección en el sitio quirúrgico; sin embargo, destacan que los profesionales de salud necesitan realizar los procedimientos de manera adecuada.The control of environmental contamination has been considered a rational measure for preventing surgical site infection. This study aims to present the current recommendations related to the preparation of the surgical team and to discuss the role of nurses in controlling environmental contamination. On the basis of current literature, we treat issues related to surgical garment and hand brushing. Studies indicate that the preparation of the surgical team constitutes an important

  15. Mixtures of truncated basis functions

    DEFF Research Database (Denmark)

    Langseth, Helge; Nielsen, Thomas Dyhre; Rumí, Rafael;

    2012-01-01

    In this paper we propose a framework, called mixtures of truncated basis functions (MoTBFs), for representing general hybrid Bayesian networks. The proposed framework generalizes both the mixture of truncated exponentials (MTEs) framework and the mixture of polynomials (MoPs) framework. Similar...... for efficiently approximating an arbitrary density function using the MoTBF framework. The transla- tion method is more flexible than existing MTE or MoP-based methods, and it supports an online/anytime tradeoff between the accuracy and the complexity of the approxima- tion. Experimental results show...

  16. Value basis for conservation policy

    Energy Technology Data Exchange (ETDEWEB)

    Leiss, W.

    1981-01-01

    This paper is a case study in attempting to apply a particular value (caring) to the domain of social policy, specifically resource conservation policy. The argument is that our consumer society erodes the social basis for the development by individuals of a sense of well-being and personal identity, and that a conservation ethic based on the concept of caring could provide a foundation in practical morality and public policy for a viable sense of well-being. Conservation, then, goes beyond eliminating wasteful consumption to encompass a public commitment that can further economic and social goals. 11 references.

  17. The physical basis of chemistry

    CERN Document Server

    Warren, Warren S

    2000-01-01

    If the text you're using for general chemistry seems to lack sufficient mathematics and physics in its presentation of classical mechanics, molecular structure, and statistics, this complementary science series title may be just what you're looking for. Written for the advanced lower-division undergraduate chemistry course, The Physical Basis of Chemistry, Second Edition, offers students an opportunity to understand and enrich the understanding of physical chemistry with some quantum mechanics, the Boltzmann distribution, and spectroscopy. Posed and answered are questions concerning eve

  18. Quadratic Hedging of Basis Risk

    Directory of Open Access Journals (Sweden)

    Hardy Hulley

    2015-02-01

    Full Text Available This paper examines a simple basis risk model based on correlated geometric Brownian motions. We apply quadratic criteria to minimize basis risk and hedge in an optimal manner. Initially, we derive the Föllmer–Schweizer decomposition for a European claim. This allows pricing and hedging under the minimal martingale measure, corresponding to the local risk-minimizing strategy. Furthermore, since the mean-variance tradeoff process is deterministic in our setup, the minimal martingale- and variance-optimal martingale measures coincide. Consequently, the mean-variance optimal strategy is easily constructed. Simple pricing and hedging formulae for put and call options are derived in terms of the Black–Scholes formula. Due to market incompleteness, these formulae depend on the drift parameters of the processes. By making a further equilibrium assumption, we derive an approximate hedging formula, which does not require knowledge of these parameters. The hedging strategies are tested using Monte Carlo experiments, and are compared with results achieved using a utility maximization approach.

  19. Internal dosimetry technical basis manual

    International Nuclear Information System (INIS)

    The internal dosimetry program at the Savannah River Site (SRS) consists of radiation protection programs and activities used to detect and evaluate intakes of radioactive material by radiation workers. Examples of such programs are: air monitoring; surface contamination monitoring; personal contamination surveys; radiobioassay; and dose assessment. The objectives of the internal dosimetry program are to demonstrate that the workplace is under control and that workers are not being exposed to radioactive material, and to detect and assess inadvertent intakes in the workplace. The Savannah River Site Internal Dosimetry Technical Basis Manual (TBM) is intended to provide a technical and philosophical discussion of the radiobioassay and dose assessment aspects of the internal dosimetry program. Detailed information on air, surface, and personal contamination surveillance programs is not given in this manual except for how these programs interface with routine and special bioassay programs

  20. Chemical basis for minimal cognition.

    Science.gov (United States)

    Hanczyc, Martin M; Ikegami, Takashi

    2010-01-01

    We have developed a simple chemical system capable of self-movement in order to study the physicochemical origins of movement. We propose how this system may be useful in the study of minimal perception and cognition. The system consists simply of an oil droplet in an aqueous environment. A chemical reaction within the oil droplet induces an instability, the symmetry of the oil droplet breaks, and the droplet begins to move through the aqueous phase. The complement of physical phenomena that is then generated indicates the presence of feedback cycles that, as will be argued, form the basis for self-regulation, homeostasis, and perhaps an extended form of autopoiesis. We discuss the result that simple chemical systems are capable of sensory-motor coupling and possess a homeodynamic state from which cognitive processes may emerge. PMID:20586578

  1. The Genetic Basis of Hydrocephalus.

    Science.gov (United States)

    Kousi, Maria; Katsanis, Nicholas

    2016-07-01

    Studies of syndromic hydrocephalus have led to the identification of >100 causative genes. Even though this work has illuminated numerous pathways associated with hydrocephalus, it has also highlighted the fact that the genetics underlying this phenotype are more complex than anticipated originally. Mendelian forms of hydrocephalus account for a small fraction of the genetic burden, with clear evidence of background-dependent effects of alleles on penetrance and expressivity of driver mutations in key developmental and homeostatic pathways. Here, we synthesize the currently implicated genes and inheritance paradigms underlying hydrocephalus, grouping causal loci into functional modules that affect discrete, albeit partially overlapping, cellular processes. These in turn have the potential to both inform pathomechanism and assist in the rational molecular classification of a clinically heterogeneous phenotype. Finally, we discuss conceptual methods that can lead to enhanced gene identification and dissection of disease basis, knowledge that will potentially form a foundation for the design of future therapeutics. PMID:27145913

  2. Internal dosimetry technical basis manual

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-20

    The internal dosimetry program at the Savannah River Site (SRS) consists of radiation protection programs and activities used to detect and evaluate intakes of radioactive material by radiation workers. Examples of such programs are: air monitoring; surface contamination monitoring; personal contamination surveys; radiobioassay; and dose assessment. The objectives of the internal dosimetry program are to demonstrate that the workplace is under control and that workers are not being exposed to radioactive material, and to detect and assess inadvertent intakes in the workplace. The Savannah River Site Internal Dosimetry Technical Basis Manual (TBM) is intended to provide a technical and philosophical discussion of the radiobioassay and dose assessment aspects of the internal dosimetry program. Detailed information on air, surface, and personal contamination surveillance programs is not given in this manual except for how these programs interface with routine and special bioassay programs.

  3. Nanotechnological Basis for Advanced Sensors

    CERN Document Server

    Reithmaier, Johann Peter; Kulisch, Wilhelm; Popov, Cyril; Petkov, Plamen

    2011-01-01

    Bringing together experts from 15 countries, this book is based on the lectures and contributions of the NATO Advanced Study Institute on “Nanotechnological Basis for Advanced Sensors” held in Sozopol, Bulgaria, 30 May - 11 June, 2010. It gives a broad overview on this topic, and includes articles on: techniques for preparation and characterization of sensor materials; different types of nanoscaled materials for sensor applications, addressing both their structure (nanoparticles, nanocomposites, nanostructured films, etc.) and chemical nature (carbon-based, oxides, glasses, etc.); and on advanced sensors that exploit nanoscience and nanotechnology. In addition, the volume represents an interdisciplinary approach with authors coming from diverse fields such as physics, chemistry, engineering, materials science and biology. A particular strength of the book is its combination of longer papers, introducing the basic knowledge on a certain topic, and brief contributions highlighting special types of sensors a...

  4. Análisis del carbono en los suelos agrícolas de España: aspectos relevantes en relación a la reconversión a la agricultura ecológica en el ámbito mediterráneo

    OpenAIRE

    Romanyà Socoró, Joan; Rovira Castellà, Pere Albert; Vallejo Calzada, Ramón

    2007-01-01

    Los niveles de carbono orgánico en suelos agrícolas son especialmente relevantes en los modelos de gestión que se basan en la reserva orgánica de nutrientes. La disminución de materia orgánica que ocurre en los suelos roturados puede en algunos casos determinar la degradación del suelo. Este hecho puede ser especialmente relevante en condiciones climáticas límite (secas y semiáridas). A partir del análisis de una base de datos de suelos españoles se discute la distribución del C en e...

  5. Vergleichende Permeabilitäts- und Penetrationsstudien in vitro an Schweinekornea und Rindernasenmukosa sowie biophysikalische Untersuchungen an potentiellen Formulierungen (Mikroemulsionen)

    OpenAIRE

    Richter, Telse Erika

    2004-01-01

    In dieser Arbeit wurden die beiden Membranen Schweinekornea und Rindernasenmukosa hinsichtlich ihrer Permeabilität für den lipophilen Arzneistoff Androstendion (AD), der sowohl zur ophthalmologischen Anwendung als auch für die nasale Applikation mit systemischer Wirkung von Interesse ist, verglichen. Zusätzlich wurden identische Versuche mit der synthetischen Membran, Nephrophan(r), durchgeführt. Neben der gepufferten Arzneistofflösung, für die aufgrund des differenzierten Membranaufbaus Pe...

  6. Borreliose de Lyme simile: uma doença emergente e relevante para a dermatologia no Brasil Lyme borreliosis simile: an emergent and relevant disease to dermatology in Brazil

    Directory of Open Access Journals (Sweden)

    Adivaldo Henrique da Fonseca

    2005-04-01

    Full Text Available Neste trabalho de revisão são apresentadas doenças relacionadas com espiroquetas do gênero Borrelia, agentes etiológicos de diferentes enfermidades comuns ao homem e a animais. Enfatizou-se a Borrelia burgdorferi lato sensu, que inclui diferentes espécies causadoras de doenças e com envolvimento sistêmico, com interesse em várias especialidades médicas, como dermatologia, reumatologia, cardiologia e neurologia. Considerando que existem diferenças quanto ao agente etiológico, além dos aspectos clínicos e laboratoriais, quando comparada com a borreliose de Lyme causada pelas Borrelia burgdorferi, B. garinii e B. afzelli, a infecção no Brasil deve ser referida como borreliose de Lyme simile. O eritema migratório recidivante é a principal manifestação clínica da borreliose existente tanto no Brasil como nos demais países. Essa lesão clássica está relacionada com a picada do carrapato vetor e inicia-se como uma mácula ou pápula cutânea avermelhada, de caráter expansivo, eventualmente surgem lesões semelhantes múltiplas a distância. A manifestação clínica da enfermidade, em especial o envolvimento cutâneo, é o parâmetro diagnóstico mais relevante, e os exames complementares sorológicos confirmam a suspeita clínica.This review article presents diseases related to spirochetes of the genus Borrelia, which are the etiological agents of many human and animal diseases. Focus was given to the Borrelia burgdorferi sensu lato complex, including nine different species that cause diseases often with multisystemic involvement and raising interest to many medical specialties, such as Dermatology, Rheumatology, Cardiology and Neurology. Due to differences concerning the etiologic agent, clinical and laboratorial presentations, when comparing with Borrelia burgdorferi, B. garinii and B. afzelli, the infection must be referred as Lyme disease-like illness in Brazil. The recurrent erythema migrans is the main clinical

  7. Identificação dos fatores relevantes na decisão da alocação dos recursos econômicos visando um trânsito seguro

    Directory of Open Access Journals (Sweden)

    Érico Veras Marques

    2010-12-01

    Full Text Available A municipalização do trânsito no Brasil, a partir do final da década de 1990, transformou o município em um importante agente social no cenário contemporâneo da educação no trânsito. A expansão das receitas dos órgãos executivos de trânsito coloca em pauta novos desafios de atuação do município, exigindo maior profissionalismo na aplicação dos recursos arrecadados, num contexto social que espera que os municípios produzam e transpareçam resultados efetivos de suas ações. Diante desta realidade, a possibilidade de se identificarem os fatores capazes de traduzir a complexa problemática de aplicação dos recursos arrecadados dos órgãos executivos de trânsito não é uma tarefa simples. A maioria das iniciativas para isso acaba falhando, principalmente pela multiplicidade de aspectos a serem considerados na abordagem do problema. Muitas vezes são omitidos ou desprezados os aspectos que deveriam ser contemplados, resultando em simplificações que acabam por produzir estruturas de avaliação incapazes de representar a realidade do processo. O presente estudo propõe-se a identificar os fatores relevantes na tomada de decisão para aplicação dos recursos arrecadados com multas de trânsito, a partir das visões dos diversos especialistas de trânsito e dos gestores de órgãos executivos de trânsito das capitais brasileiras. A identificação desses fatores foi possível a partir da utilização da Técnica Delphi, a qual foi realizada através de sete rodadas de entrevistas com 12 especialistas e aplicação de um questionário junto aos gestores de 10 das maiores capitais do pais. O produto final da pesquisa foi a construção da estrutura hierárquica desses fatores e suas respectivas dimensões.

  8. Tank characterization technical sampling basis

    Energy Technology Data Exchange (ETDEWEB)

    Brown, T.M.

    1998-04-28

    Tank Characterization Technical Sampling Basis (this document) is the first step of an in place working process to plan characterization activities in an optimal manner. This document will be used to develop the revision of the Waste Information Requirements Document (WIRD) (Winkelman et al. 1997) and ultimately, to create sampling schedules. The revised WIRD will define all Characterization Project activities over the course of subsequent fiscal years 1999 through 2002. This document establishes priorities for sampling and characterization activities conducted under the Tank Waste Remediation System (TWRS) Tank Waste Characterization Project. The Tank Waste Characterization Project is designed to provide all TWRS programs with information describing the physical, chemical, and radiological properties of the contents of waste storage tanks at the Hanford Site. These tanks contain radioactive waste generated from the production of nuclear weapons materials at the Hanford Site. The waste composition varies from tank to tank because of the large number of chemical processes that were used when producing nuclear weapons materials over the years and because the wastes were mixed during efforts to better use tank storage space. The Tank Waste Characterization Project mission is to provide information and waste sample material necessary for TWRS to define and maintain safe interim storage and to process waste fractions into stable forms for ultimate disposal. This document integrates the information needed to address safety issues, regulatory requirements, and retrieval, treatment, and immobilization requirements. Characterization sampling to support tank farm operational needs is also discussed.

  9. Community treatment orders: Bioethical basis

    Directory of Open Access Journals (Sweden)

    José Manuel Bertolín Guillén

    2011-09-01

    Full Text Available Background and Objectives: Numerous opinions and medico-legal controversies have arisen up to the date from community treatment orders in Western countries, but underlying bioethical questions have not been specifically studied. The aim of this work is to contribute to further clarify the bioethical conflicts arising from community treatment orders. Methods: The bioethical deliberation of the author is principally based on what can be considered the deontologist-principlist dominant paradigm. These principles, as first described by Beauchamp and Childress in 1979, will be applied in this work to the actual situation of involuntary outpatient treatment. Results: The author's deliberation considers that community treatment orders are consistent first with the deontologist-principlist dominant paradigm of practical reason, respecting its four general categories of basic principles. It also respects the principles of the medical ethics of virtue, subsumed in the personalism of ontological matrix, in the same way as its ethos affects the intrinsic purpose which is the dignity of the person; and with the consequentialist utilitarianism because it seeks the proportionality of the common good. A community treatment order prescription must ultimately be based on a bioethical exercise of responsibility by the clinician, judiciously weighing up the classic principal prima facie duties which must necessarily be translated into a real duty referring to a specific patient and context. Conclusions: Community treatment orders are seen as a method of therapeutic intervention with a bioethical basis resistant to criticism.

  10. [Neural basis of procedural memory].

    Science.gov (United States)

    Mochizuki-Kawai, Hiroko

    2008-07-01

    Procedural memory is acquired by trial and error. Our daily life is supported by a number of procedural memories such as those for riding bicycle, typing, reading words, etc. Procedural memory is divided into 3 types; motor, perceptual, and cognitive. Here, the author reviews the cognitive and neural basis of procedural memory according to these 3 types. It is reported that the basal ganglia or cerebellum dysfunction causes deficits in procedural memory. Compared with age-matched healthy participants, patients with Parkinson disease (PD), Huntington disease (HD) or spinocerebellar degeneration (SCD) show deterioration in improvements in motor-type procedural memory tasks. Previous neuroimaging studies have reported that motor-type procedural memory may be supported by multiple brain regions, including the frontal and parietal regions as well as the basal ganglia (cerebellum); this was found with a serial reaction time task (SRT task). Although 2 other types of procedural memory are also maintained by multiple brain regions, the related cerebral areas depend on the type of memory. For example, it was suggested that acquisition of the perceptual type of procedural memory (e.g., ability to read mirror images of words) might be maintained by the bilateral fusiform region, while the acquisition of cognitive procedural memory might be supported by the frontal, parietal, or cerebellar regions as well as the basal ganglia. In the future, we need to cleary understand the neural "network" related to the procedural memory. PMID:18646622

  11. Basis Document for Sludge Stabilization

    CERN Document Server

    Risenmay, H R

    2001-01-01

    DOE-RL recently issued Safety Evaluation Report (SER) amendments to the PFP Final Safety Analysis Report, HNF-SD-CP-SAR-021 Rev. 2. The Justification for Continued Operations for 2736-ZB and plutonium oxides in BTCs Safety Basis change (letter DOE-RL ABD-074) was approved by one of the SERs. Also approved by SER was the revised accident analysis for Magnesium Hydroxide Precipitation Process (MHPP) gloveboxes HC-230C-3 and HC-230C-5 containing increased glovebox inventories and corresponding increases in seismic release consequence. Numerous implementing documents require revision and issuance to implement the SER approvals. The SER plutonium oxides into BTCs specifically limited the SER scope to ''pure or clean oxides, i.e., 85 wt% or grater Pu, in this feed change'' (SER Section 3.0 Base Information paragraph 4 [page 11]). Comprehensive USQ Evaluation PFP-2001-12 addressed the packaging of Pu alloy metals into BTCs, and the packaging of Pu alloy oxides (powders) into food pack cans and determined that the ac...

  12. Basis Document for Sludge Stabilization

    International Nuclear Information System (INIS)

    DOE-RL recently issued Safety Evaluation Report (SER) amendments to the PFP Final Safety Analysis Report, HNF-SD-CP-SAR-021 Rev. 2. The Justification for Continued Operations for 2736-ZB and plutonium oxides in BTCs Safety Basis change (letter DOE-RL ABD-074) was approved by one of the SERs. Also approved by SER was the revised accident analysis for Magnesium Hydroxide Precipitation Process (MHPP) gloveboxes HC-230C-3 and HC-230C-5 containing increased glovebox inventories and corresponding increases in seismic release consequence. Numerous implementing documents require revision and issuance to implement the SER approvals. The SER authorizing plutonium oxides into BTCs specifically limited the SER authorization scope to ''pure or clean oxides, i.e., 85 wt% or grater Pu, in this feed change'' (SER Section 3.0 Base Information paragraph 4 [page 11]). Comprehensive USQ Evaluation PFP-2001-12 addressed the packaging of Pu alloy metals into BTCs, and the packaging of Pu alloy oxides (powders) into food pack cans and determined that the activities did not represent an USQ. The same information used to make the PFP-2001-12 negative USQ determination is applicable to packaging Pu alloy powders (DOES NOT INCLUDE STABILIZED MHPP MATERIALS OR OXIDES OF MOLYBDATES) into BTCs. Information from USQ Evaluation PFP-2001-12 is included in this USQ Evaluation for packaging of relatively pure Pu oxides and Pu alloy oxides into BTCs

  13. Advanced Fuel Cycle Cost Basis

    Energy Technology Data Exchange (ETDEWEB)

    D. E. Shropshire; K. A. Williams; W. B. Boore; J. D. Smith; B. W. Dixon; M. Dunzik-Gougar; R. D. Adams; D. Gombert; E. Schneider

    2009-12-01

    This report, commissioned by the U.S. Department of Energy (DOE), provides a comprehensive set of cost data supporting a cost analysis for the relative economic comparison of options for use in the Advanced Fuel Cycle Initiative (AFCI) Program. The report describes the AFCI cost basis development process, reference information on AFCI cost modules, a procedure for estimating fuel cycle costs, economic evaluation guidelines, and a discussion on the integration of cost data into economic computer models. This report contains reference cost data for 25 cost modules—23 fuel cycle cost modules and 2 reactor modules. The cost modules were developed in the areas of natural uranium mining and milling, conversion, enrichment, depleted uranium disposition, fuel fabrication, interim spent fuel storage, reprocessing, waste conditioning, spent nuclear fuel (SNF) packaging, long-term monitored retrievable storage, near surface disposal of low-level waste (LLW), geologic repository and other disposal concepts, and transportation processes for nuclear fuel, LLW, SNF, transuranic, and high-level waste.

  14. Advanced Fuel Cycle Cost Basis

    Energy Technology Data Exchange (ETDEWEB)

    D. E. Shropshire; K. A. Williams; W. B. Boore; J. D. Smith; B. W. Dixon; M. Dunzik-Gougar; R. D. Adams; D. Gombert; E. Schneider

    2008-03-01

    This report, commissioned by the U.S. Department of Energy (DOE), provides a comprehensive set of cost data supporting a cost analysis for the relative economic comparison of options for use in the Advanced Fuel Cycle Initiative (AFCI) Program. The report describes the AFCI cost basis development process, reference information on AFCI cost modules, a procedure for estimating fuel cycle costs, economic evaluation guidelines, and a discussion on the integration of cost data into economic computer models. This report contains reference cost data for 25 cost modules—23 fuel cycle cost modules and 2 reactor modules. The cost modules were developed in the areas of natural uranium mining and milling, conversion, enrichment, depleted uranium disposition, fuel fabrication, interim spent fuel storage, reprocessing, waste conditioning, spent nuclear fuel (SNF) packaging, long-term monitored retrievable storage, near surface disposal of low-level waste (LLW), geologic repository and other disposal concepts, and transportation processes for nuclear fuel, LLW, SNF, transuranic, and high-level waste.

  15. Advanced Fuel Cycle Cost Basis

    Energy Technology Data Exchange (ETDEWEB)

    D. E. Shropshire; K. A. Williams; W. B. Boore; J. D. Smith; B. W. Dixon; M. Dunzik-Gougar; R. D. Adams; D. Gombert

    2007-04-01

    This report, commissioned by the U.S. Department of Energy (DOE), provides a comprehensive set of cost data supporting a cost analysis for the relative economic comparison of options for use in the Advanced Fuel Cycle Initiative (AFCI) Program. The report describes the AFCI cost basis development process, reference information on AFCI cost modules, a procedure for estimating fuel cycle costs, economic evaluation guidelines, and a discussion on the integration of cost data into economic computer models. This report contains reference cost data for 26 cost modules—24 fuel cycle cost modules and 2 reactor modules. The cost modules were developed in the areas of natural uranium mining and milling, conversion, enrichment, depleted uranium disposition, fuel fabrication, interim spent fuel storage, reprocessing, waste conditioning, spent nuclear fuel (SNF) packaging, long-term monitored retrievable storage, near surface disposal of low-level waste (LLW), geologic repository and other disposal concepts, and transportation processes for nuclear fuel, LLW, SNF, and high-level waste.

  16. Leerteoretiese basis van die andragogie

    Directory of Open Access Journals (Sweden)

    C. J. A. Simpson

    1991-06-01

    Full Text Available Learning theory basis of andragogy. A cursory glance at andragogy creates the impression that humanistic learning theory plays an all encompassing role in the learner centered approach andragogy espouses. A closer look, however, reveals that Knowles (1973, after having made an intensive study of learning theory, created an extensive framework within which human resource development can take place. The fact that Knowles attracted critique from different areas, led to a need to ascertain the role different learning theories, if any, played in the emergence of andragogy. Having looked at the assumptions displayed by the andragogical approach, as well as a comparison of different learning theories and their connection with andragogy, it became clear that andragogy contains elements of various learning theories in an adapted way. These adaptations resulted in an approach to adult education in which learners are given the opportunity to be part of the learning process in such a way that they themselves contribute to the development which takes place. Opsomming Met 'n eerste oogopslag wil dit voorkom asof humanistiese leerteorie 'n oorheersende rol in die leerdergesentreerde benadering van andragogie speel. By nadere ondersoek blyk dit egter dat Knowles (1973, na 'n deeglike studie van verskillende leerteoretiese beginsels, 'n omvangryke raamwerk geskep het waarbinne, aan die hand van verskeie aangepaste leerteoretiese beginsels, menslike hulpbronontwikkeling kan plaasvind. As gevolg van die feit dat Knowles vanuit verskillende oorde kritiek op die lyf geloop het, is besluit om die rol wat verskillende leerteorieë in andragogie speel, te bestudeer. Dit blyk dat andragogie nie net elemente van verskillende leerteorieë bevat nie, maar dat toepaslike aspekte van die teoriee wat ondersoek is, benut en aangepas is om 'n geintegreerde benadering te bewerkstellig waarin veral volwassene-leerders by leergeleenthede en hulle selfontwikkeling betrek word.

  17. Transferable basis sets of numerical atomic orbitals

    NARCIS (Netherlands)

    M.J. Louwerse; G. Rothenberg

    2012-01-01

    We show that numerical atomic orbital basis sets that are variationally optimized for specific compounds are biased and not fully transferable to other compounds. The situation improves when the basis sets are optimized for several compounds and a compromise is made. We demonstrate this for basis se

  18. Constructing a quasi-Legendre basis based on the C-Bézier basis

    Institute of Scientific and Technical Information of China (English)

    HUANG Yu; WANG Guozhao

    2005-01-01

    In the spaceГn = span{sint, cost, 1, t, t2, …, tn- 2[, a C-Bezier basis is constructed by an integral approach. However, the C-Bezier basis is not orthogonal. For some applications, we construct an orthogonal basis based on the C-Bezier basis, which has remarkable properties similar to that of the Legendre basis. Then we derive the transformation matrices that convert the C-Bezier basis and the orthogonal basis into each other. As an example of application, we apply this orthogonal basis to the degree reduction approximation of the C-Bezier curves.

  19. Estimating the CCSD basis-set limit energy from small basis sets: basis-set extrapolations vs additivity schemes

    Energy Technology Data Exchange (ETDEWEB)

    Spackman, Peter R.; Karton, Amir, E-mail: amir.karton@uwa.edu.au [School of Chemistry and Biochemistry, The University of Western Australia, Perth, WA 6009 (Australia)

    2015-05-15

    Coupled cluster calculations with all single and double excitations (CCSD) converge exceedingly slowly with the size of the one-particle basis set. We assess the performance of a number of approaches for obtaining CCSD correlation energies close to the complete basis-set limit in conjunction with relatively small DZ and TZ basis sets. These include global and system-dependent extrapolations based on the A + B/L{sup α} two-point extrapolation formula, and the well-known additivity approach that uses an MP2-based basis-set-correction term. We show that the basis set convergence rate can change dramatically between different systems(e.g.it is slower for molecules with polar bonds and/or second-row elements). The system-dependent basis-set extrapolation scheme, in which unique basis-set extrapolation exponents for each system are obtained from lower-cost MP2 calculations, significantly accelerates the basis-set convergence relative to the global extrapolations. Nevertheless, we find that the simple MP2-based basis-set additivity scheme outperforms the extrapolation approaches. For example, the following root-mean-squared deviations are obtained for the 140 basis-set limit CCSD atomization energies in the W4-11 database: 9.1 (global extrapolation), 3.7 (system-dependent extrapolation), and 2.4 (additivity scheme) kJ mol{sup –1}. The CCSD energy in these approximations is obtained from basis sets of up to TZ quality and the latter two approaches require additional MP2 calculations with basis sets of up to QZ quality. We also assess the performance of the basis-set extrapolations and additivity schemes for a set of 20 basis-set limit CCSD atomization energies of larger molecules including amino acids, DNA/RNA bases, aromatic compounds, and platonic hydrocarbon cages. We obtain the following RMSDs for the above methods: 10.2 (global extrapolation), 5.7 (system-dependent extrapolation), and 2.9 (additivity scheme) kJ mol{sup –1}.

  20. Determination of Design Basis Earthquake ground motion

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Muneaki [Japan Atomic Power Co., Tokyo (Japan)

    1997-03-01

    This paper describes principle of determining of Design Basis Earthquake following the Examination Guide, some examples on actual sites including earthquake sources to be considered, earthquake response spectrum and simulated seismic waves. In sppendix of this paper, furthermore, seismic safety review for N.P.P designed before publication of the Examination Guide was summarized with Check Basis Earthquake. (J.P.N.)

  1. 14 CFR 1203.100 - Legal basis.

    Science.gov (United States)

    2010-01-01

    ...”), and the standards for such classification, are established by the “the Order” (E.O. 12958, 3 CFR, 1996... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Legal basis. 1203.100 Section 1203.100....100 Legal basis. (a) Executive Order 12958 (hereinafter referred to as “the Order”)....

  2. Advanced Test Reactor Safety Basis Upgrade Lessons Learned Relative to Design Basis Verification and Safety Basis Management

    International Nuclear Information System (INIS)

    The Advanced Test Reactor (ATR) is a pressurized light-water reactor with a design thermal power of 250 MW. The principal function of the ATR is to provide a high neutron flux for testing reactor fuels and other materials. The reactor also provides other irradiation services such as radioisotope production. The ATR and its support facilities are located at the Test Reactor Area of the Idaho National Engineering and Environmental Laboratory (INEEL). An audit conducted by the Department of Energy's Office of Independent Oversight and Performance Assurance (DOE OA) raised concerns that design conditions at the ATR were not adequately analyzed in the safety analysis and that legacy design basis management practices had the potential to further impact safe operation of the facility.1 The concerns identified by the audit team, and issues raised during additional reviews performed by ATR safety analysts, were evaluated through the unreviewed safety question process resulting in shutdown of the ATR for more than three months while these concerns were resolved. Past management of the ATR safety basis, relative to facility design basis management and change control, led to concerns that discrepancies in the safety basis may have developed. Although not required by DOE orders or regulations, not performing design basis verification in conjunction with development of the 10 CFR 830 Subpart B upgraded safety basis allowed these potential weaknesses to be carried forward. Configuration management and a clear definition of the existing facility design basis have a direct relation to developing and maintaining a high quality safety basis which properly identifies and mitigates all hazards and postulated accident conditions. These relations and the impact of past safety basis management practices have been reviewed in order to identify lessons learned from the safety basis upgrade process and appropriate actions to resolve possible concerns with respect to the current ATR safety

  3. Brazilian industry of natural gas: criteria for definition of relevant markets concerning the defense of competition; Industria brasileira do gas natural: criterios de definicao dos mercados relevantes para efeito de defesa da concorrencia

    Energy Technology Data Exchange (ETDEWEB)

    Mano, Gustavo; Tiryaki, Gisele Ferreira [Universidade de Salvador (UNIFACS), BA (Brazil)

    2008-07-01

    A key point in the examination of the legality of antitrust practices is the delimitation of the relevant markets where the economic relations object of the analysis take place. This is the basis for the evaluation of the market power of the agents involved and the possible harm to competition they may cause. This work offers a study of the criteria for the determination of the relevant market in the scope of the natural gas industry in Brazil. It aims at identifying the performance of the agencies taking part in the Brazilian Antitrust System (SBDC) with regards to the examination of the related antitrust practices. These agencies work in connection with the National Petroleum, Natural Gas and Biofuels Regulatory Agency (ANP), which is responsible for issuing technical reports on the subjects related to its area of competence. The analysis presented here has the main goal of verifying if the most important technical, operational and legal aspects are being adequately considered by the SBDC and ANP in the definition of the relevant markets as a basis for the judgment of the antitrust practices, and if they are coherent with the principles for fostering economic competition. The results points out that, despite the successful cooperation between the SBDC and the ANP, there are the used definition of the relevant markets for the natural gas industry still needs refinement. (author)

  4. Relative integral basis for algebraic number fields

    OpenAIRE

    Mohmood Haghighi

    1986-01-01

    At first conditions are given for existence of a relative integral basis for OK≅Okn−1⊕I with [K;k]=n. Then the constrtiction of the ideal I in OK≅Okn−1⊕I is given for proof of existence of a relative integral basis for OK4(m1,m2)/Ok(​m3). Finally existence and construction of the relative integral basis for OK6(n3,−3)/Ok3(n3),OK6(n3,−3)/Ok2(−3) for some values of n are given.

  5. The Pattern Basis Approach to Circuit Complexity

    OpenAIRE

    Smith, Bruce K.

    2016-01-01

    We describe and motivate a proposed new approach to lowerbounding the circuit complexity of boolean functions, based on a new formalization of "patterns" as elements of a special basis of the vector space of all truth table properties. We prove that a "pattern basis" with certain properties would lead to a useful complexity formula of a specific form, and speculate on how to find such a basis. This formula might take as long to compute on arbitrary functions as a brute-force search among circ...

  6. Generalized multiscale radial basis function networks.

    Science.gov (United States)

    Billings, Stephen A; Wei, Hua-Liang; Balikhin, Michael A

    2007-12-01

    A novel modelling framework is proposed for constructing parsimonious and flexible multiscale radial basis function networks (RBF). Unlike a conventional standard single scale RBF network, where all the basis functions have a common kernel width, the new network structure adopts multiscale Gaussian functions as the bases, where each selected centre has multiple kernel widths, to provide more flexible representations with better generalization properties for general nonlinear dynamical systems. As a direct extension of the traditional single scale Gaussian networks, the new multiscale network is easy to implement and is quick to learn using standard learning algorithms. A k-means clustering algorithm and an improved orthogonal least squares (OLS) algorithm are used to determine the unknown parameters in the network model including the centres and widths of the basis functions, and the weights between the basis functions. It is demonstrated that the new network can lead to a parsimonious model with much better generalization property compared with the traditional single width RBF networks.

  7. The Teleological Resocialization: theoretical-praxeological basis

    OpenAIRE

    Sławomir Sobczak

    2011-01-01

    Resocialization and Social Prevention is a theoretical and a praxeological subject, thus teleology of resocialization as its building block should relate both to its theoretical and practical aspects, i.e. to goals and postulates formed on the basis of paradigms and diagnosis. In the article are pointed out the reasons for forming teleology of resocialization due to the foundation of fundamental thinking, i.e. monistic basis (idealism, materialism) and pluralism (realism) and also the outcome...

  8. Nanoplasmonics simulations at the basis set limit through completeness-optimized, local numerical basis sets

    Energy Technology Data Exchange (ETDEWEB)

    Rossi, Tuomas P., E-mail: tuomas.rossi@alumni.aalto.fi; Sakko, Arto; Puska, Martti J. [COMP Centre of Excellence, Department of Applied Physics, Aalto University School of Science, P.O. Box 11100, FI-00076 Aalto (Finland); Lehtola, Susi, E-mail: susi.lehtola@alumni.helsinki.fi [COMP Centre of Excellence, Department of Applied Physics, Aalto University School of Science, P.O. Box 11100, FI-00076 Aalto (Finland); Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Nieminen, Risto M. [COMP Centre of Excellence, Department of Applied Physics, Aalto University School of Science, P.O. Box 11100, FI-00076 Aalto (Finland); Dean’s Office, Aalto University School of Science, P.O. Box 11000, FI-00076 Aalto (Finland)

    2015-03-07

    We present an approach for generating local numerical basis sets of improving accuracy for first-principles nanoplasmonics simulations within time-dependent density functional theory. The method is demonstrated for copper, silver, and gold nanoparticles that are of experimental interest but computationally demanding due to the semi-core d-electrons that affect their plasmonic response. The basis sets are constructed by augmenting numerical atomic orbital basis sets by truncated Gaussian-type orbitals generated by the completeness-optimization scheme, which is applied to the photoabsorption spectra of homoatomic metal atom dimers. We obtain basis sets of improving accuracy up to the complete basis set limit and demonstrate that the performance of the basis sets transfers to simulations of larger nanoparticles and nanoalloys as well as to calculations with various exchange-correlation functionals. This work promotes the use of the local basis set approach of controllable accuracy in first-principles nanoplasmonics simulations and beyond.

  9. Ecological valuation of mechanic-biological waste treatment and waste combustion on the basis of energy balances and air pollutant balances; Oekologische Bewertung der mechanisch-biologischen Restabfallbehandlung und der Muellverbrennung auf Basis von Energie- und Schadgasbilanzen

    Energy Technology Data Exchange (ETDEWEB)

    Wallmann, R.

    1999-04-01

    The work aims at an ecological valuation of air pollutant emissions and energy consumption as particularly relevant aspects of waste treatment and waste combustion plants, based on new scientific results, in order to draw up ecological budgets and make system comparisons in waste treatment. The target set is particularly effectively achieved by the following: documentation and scientific derivation of relevant boundary conditions, careful surveying and data processing for the purpose of making up an ecological budget, and objective valuation and interpretation of results. The high transparency of the methodics should be emphasized. They make the results obtained conclusive and verifiable. (orig.) [Deutsch] Ziel der vorliegenden Arbeit ist die oekologische Bewertung der besonders relevanten Aspekte Abluftemissionen und Energieverbrauch von MBA und MVA auf Basis aktueller Forschungsergebnisse als Grundlage fuer Oekobilanzen und Systemvergleiche zur Restabfallbehandlung. Diese Zielvorgabe wird durch die Dokumentation und wissenschaftliche Herleitung relevanter Rahmenbedingungen, sorgfaeltige Erhebung und Aufbereitung der Daten unter Gesichtspunkten der Erstellung einer Oekobilanz und letztendlich aufgrund der objektiven Bewertung und Interpretation der Ergebnisse im besonderen Masse erreicht. Besonders hervorzuheben hierbei ist die hohe Transparenz bei der methodischen Vorgehensweise. Die ermittelten Ergebnisse sind somit nachvollziehbar und ueberpruefbar. (orig.)

  10. Heavy quarkonium in a holographic basis

    Science.gov (United States)

    Li, Yang; Maris, Pieter; Zhao, Xingbo; Vary, James P.

    2016-07-01

    We study the heavy quarkonium within the basis light-front quantization approach. We implement the one-gluon exchange interaction and a confining potential inspired by light-front holography. We adopt the holographic light-front wavefunction (LFWF) as our basis function and solve the non-perturbative dynamics by diagonalizing the Hamiltonian matrix. We obtain the mass spectrum for charmonium and bottomonium. With the obtained LFWFs, we also compute the decay constants and the charge form factors for selected eigenstates. The results are compared with the experimental measurements and with other established methods.

  11. Heavy quarkonium in a holographic basis

    Directory of Open Access Journals (Sweden)

    Yang Li

    2016-07-01

    Full Text Available We study the heavy quarkonium within the basis light-front quantization approach. We implement the one-gluon exchange interaction and a confining potential inspired by light-front holography. We adopt the holographic light-front wavefunction (LFWF as our basis function and solve the non-perturbative dynamics by diagonalizing the Hamiltonian matrix. We obtain the mass spectrum for charmonium and bottomonium. With the obtained LFWFs, we also compute the decay constants and the charge form factors for selected eigenstates. The results are compared with the experimental measurements and with other established methods.

  12. Leptogenesis, Yukawa Textures and Weak Basis Invariants

    CERN Document Server

    Branco, Gustavo Castello; Silva-Marcos, J I; Branco, Gustavo C.

    2006-01-01

    We show that a large class of sets of leptonic texture zeros considered in the literature imply the vanishing of certain CP-odd weak-basis invariants. These invariant conditions enable one to recognize a flavour model corresponding to a set of texture zeros, when written in an arbitrary weak-basis where the zeros are not manifest. We also analyse the r\\^ ole of texture zeros in allowing for a connection between leptogenesis and low-energy leptonic masses, mixing and CP violation. For some of the textures the variables relevant for leptogenesis can be fully determined in terms of low energy parameters and heavy neutrino masses.

  13. Five Lectures on Radial Basis Functions

    DEFF Research Database (Denmark)

    Powell, Mike J.D.

    2005-01-01

    Professor Mike J. D. Powell spent three weeks at IMM in November - December 2004. During the visit he gave five lectures on radial basis functions. These notes are a TeXified version of his hand-outs, made by Hans Bruun Nielsen, IMM.......Professor Mike J. D. Powell spent three weeks at IMM in November - December 2004. During the visit he gave five lectures on radial basis functions. These notes are a TeXified version of his hand-outs, made by Hans Bruun Nielsen, IMM....

  14. 42 CFR 409.1 - Statutory basis.

    Science.gov (United States)

    2010-10-01

    ...) Sections 1812 and 1813 establish the scope of benefits of the hospital insurance program under Medicare... CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM HOSPITAL INSURANCE BENEFITS Hospital Insurance Benefits: General Provisions § 409.1 Statutory basis....

  15. Wideband Characteristic Basis Functions in Radiation Problems

    Directory of Open Access Journals (Sweden)

    A. A. Kucharski

    2012-06-01

    Full Text Available In this paper, the use of characteristic basis function (CBF method, augmented by the application of asymptotic waveform evaluation (AWE technique is analyzed in the context of the application to radiation problems. Both conventional and wideband CBFs are applied to the analysis of wire and planar antennas.

  16. 42 CFR 436.2 - Basis.

    Science.gov (United States)

    2010-10-01

    ... Definitions § 436.2 Basis. This part implements the following sections of the Act and public laws that state.... 1902(a)(17)Standards for determining eligibility; flexibility in the application of income eligibility...)Definition f essential person. 1905(d)(2)Definition of resident of an intermediate care facility for...

  17. The Neuropsychological Basis of Childhood Psychopathology

    Science.gov (United States)

    Davis, Andrew S.

    2006-01-01

    A clear link exists between neurological dysfunction and psychopathology in children, as evidenced by research on the sequelae of developmental childhood brain impairment, the neuropsychological investigation of children with psychiatric disorders, and neuroimaging research. Understanding the neuropsychological basis of a disorder helps teachers,…

  18. Analysis of radial basis function interpolation approach

    Institute of Scientific and Technical Information of China (English)

    Zou You-Long; Hu Fa-Long; Zhou Can-Can; Li Chao-Liu; Dunn Keh-Jim

    2013-01-01

    The radial basis function (RBF) interpolation approach proposed by Freedman is used to solve inverse problems encountered in well-logging and other petrophysical issues. The approach is to predict petrophysical properties in the laboratory on the basis of physical rock datasets, which include the formation factor, viscosity, permeability, and molecular composition. However, this approach does not consider the effect of spatial distribution of the calibration data on the interpolation result. This study proposes a new RBF interpolation approach based on the Freedman's RBF interpolation approach, by which the unit basis functions are uniformly populated in the space domain. The inverse results of the two approaches are comparatively analyzed by using our datasets. We determine that although the interpolation effects of the two approaches are equivalent, the new approach is more flexible and beneficial for reducing the number of basis functions when the database is large, resulting in simplification of the interpolation function expression. However, the predicted results of the central data are not sufficiently satisfied when the data clusters are far apart.

  19. 340 waste handling facility interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    VAIL, T.S.

    1999-04-01

    This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people.

  20. An evolutionary basis for pollination ecology

    NARCIS (Netherlands)

    Willemstein, S.C.

    1987-01-01

    In the introduction and chapter 2 the incentives and way of reasoning are given for the description of an evolutionary basis of pollination ecology. Starting from the until recently rather anecdotical character of the study of pollination ecology as a whole, and in the absence of large-scale correla

  1. A Physical Basis for Color Constancy

    NARCIS (Netherlands)

    J.M. Geusebroek; R. van den Boomgaard; A.W.M. Smeulders; Th. Gevers

    2002-01-01

    A fundamental problem in psycophysical experiments is that significant conclusions are hard to draw due to the complex experimental environment necessary to examine color constancy. An alternative approach to reveal the mechanisms involved in color constancy is by modeling the physical basis for col

  2. Dynamic programming using radial basis functions

    OpenAIRE

    Junge, Oliver; Schreiber, Alex

    2014-01-01

    We propose a discretization of the optimality principle in dynamic programming based on radial basis functions and Shepard's moving least squares approximation method. We prove convergence of the approximate optimal value function to the true one and present several numerical experiments.

  3. The Contextualist Basis of Scientific Explanation

    Science.gov (United States)

    Guo, Guichun

    2014-03-01

    From perspectives of contextual structure, elements and features, this paper analyses the contextualist basis of scientific explanation. It is articulated that contextual analysis specifies the boundary conditions of syntactics, semantics, and pragmatics, clarifies the essence and value-orientation, constructs a conversational platform, and unveils the progress condition and historical continuity of scientific explanation.

  4. 340 waste handling facility interim safety basis

    International Nuclear Information System (INIS)

    This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people

  5. On Sociolinguistic Theoretical Basis of Brand Name

    Institute of Scientific and Technical Information of China (English)

    曹海洋; 司宇婷

    2015-01-01

    Brand names are the offspring of highly development of market economics, and play a crucial role in modern society. This paper discusses the soci-olinguistic theoretical basis of brand name. Attention should be paid to the cultural factors of brand naming, including customs and manners, religious beliefs, ethics, regional culture and so on.

  6. 75 FR 75896 - Basis Reporting by Securities Brokers and Basis Determination for Stock

    Science.gov (United States)

    2010-12-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR 1 RIN 1545-BI66 Basis Reporting by Securities Brokers and Basis Determination for Stock Correction In rule document 2010-25504 beginning on page 64072 in the issue of...

  7. 75 FR 6166 - Basis Reporting by Securities Brokers and Basis Determination for Stock

    Science.gov (United States)

    2010-02-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Parts, 1, 31, and 301 RIN 1545-Bl66 Basis Reporting by Securities Brokers and Basis Determination for Stock Correction In proposed rule document E9-29855 beginning on...

  8. Compilation and evaluation of published and unpublished data of relevant mineral oil additives and their combustion products; Zusammenstellung und Bewertung der bekannten Daten ueber relevante Mineraloel-Additive und ihre Verbrennungsprodukte

    Energy Technology Data Exchange (ETDEWEB)

    Keller, D.; Boehncke, A.; Mangelsdorf, I. [Fraunhofer-Institut fuer Toxikologie und Aerosolforschung (ITA), Hannover (Germany)

    1999-06-01

    The objective of this study is to collect and evaluate environmentally relevant data on mineral oil additives and their combustion products. In addition, their concentration ranges, chemistry and functions in the mineral oils are described. Lubricant and fuel additives belong to the quantitatively most important chemicals with a total quantity of 84600 tons estimated for Germany 1997/98 (57400 tons of lubricant additives, 27200 tons of fuel additives). They determine substantially the characteristic profile of engine oils, gasoline and diesel. Main lubricant additive families are detergents, dispersants, antioxidant / antiwear agents (ZDTP), inhibitors, and viscosity modifiers. Examples for fuel additives are detergents, antioxidants, corrosion inhibitors, cetane improvers (diesel), and wax crystal modifiers (diesel). Based on the information available in the literature and provided by the manufacturers the environmental fate of the additives is explored, and inventories (calculations of the input and output) are presented. Data for emission volumes were calculated on this basis and additional 'reasonable worst case' assumptions. But as measurement data in this area is very limited, the calculated emissions are uncertain. Comparison of the emitted additive combustion products (CO{sub 2}, CO, NO{sub 2}, NMVOC, particulate matter) with exhaust limit values for tail pipe emissions and total traffic emissions in Germany showed that the contribution of additive combustion products to particles is more significant than to other fractions. The results of the calculations indicate that the portion of mineral oil additives of the traffic-dependent particle emissions in Germany is approximately 7% (ca. 3/5 from lubricant additives and ca. 2/5 from fuel additives). (orig.) [German] Ziel dieser Studie ist es, umweltrelevante Daten zu Mineraloel-Additiven und ihren Verbrennungsprodukten zusammenzustellen und zu bewerten. Hierzu werden u.a. auch die Additiv

  9. Radioactive Waste Management BasisApril 2006

    Energy Technology Data Exchange (ETDEWEB)

    Perkins, B K

    2011-08-31

    This Radioactive Waste Management Basis (RWMB) documents radioactive waste management practices adopted at Lawrence Livermore National Laboratory (LLNL) pursuant to Department of Energy (DOE) Order 435.1, Radioactive Waste Management. The purpose of this Radioactive Waste Management Basis is to describe the systematic approach for planning, executing, and evaluating the management of radioactive waste at LLNL. The implementation of this document will ensure that waste management activities at LLNL are conducted in compliance with the requirements of DOE Order 435.1, Radioactive Waste Management, and the Implementation Guide for DOE Manual 435.1-1, Radioactive Waste Management Manual. Technical justification is provided where methods for meeting the requirements of DOE Order 435.1 deviate from the DOE Manual 435.1-1 and Implementation Guide.

  10. RATIONAL BASIS FOR SUSPENDED SEDIMENT MODELING

    Institute of Scientific and Technical Information of China (English)

    Jianjun ZHOU; Binliang LIN; Bingnan LIN

    2003-01-01

    This paper presents a rational basis to model the transport of suspended sediment. The looseboundary condition for 3D models and the adjustment coefficients for both the depth-integrated 2D and laterally integrated 1D models are treated comprehensively. A combination of Dirichlet and Neumann conditions is proposed as the loose-boundary condition. The adjustment coefficient for 2D models is obtained on the basis of the proposed boundary condition and analytical solutions developed for some simple cases of non-equilibrium transport of sediment in uniform flows. The adjustment coefficient for 1D models for natural rivers is further obtained from lateral integration. Comparisons with analytical solutions and a considerable amount of laboratory and prototype data show that mathematical models developed along the proposed line of attack would well simulate the transport of suspended sediment in practical problems.

  11. The biochemical basis of hereditary fructose intolerance.

    Science.gov (United States)

    Bouteldja, Nadia; Timson, David J

    2010-04-01

    Hereditary fructose intolerance is a rare, but potentially lethal, inherited disorder of fructose metabolism, caused by mutation of the aldolase B gene. Treatment currently relies solely on dietary restriction of problematic sugars. Biochemical study of defective aldolase B enzymes is key to revealing the molecular basis of the disease and providing a stronger basis for improved treatment and diagnosis. Such studies have revealed changes in enzyme activity, stability and oligomerisation. However, linking these changes to disease phenotypes has not always been straightforward. This review gives a general overview of the features of hereditary fructose intolerance, then concentrates on the biochemistry of the AP variant (Ala149Pro variant of aldolase B) and molecular pathological consequences of mutation of the aldolase B gene.

  12. Basis of valve operator selection for SMART

    International Nuclear Information System (INIS)

    SMART, an integral reactor with enhanced safety and operability, is under development for use of the nuclear energy. The valve operator of SMART system were selected through the data survey and technical review of potential valve fabrication vendors, and it will provide the establishment and optimization of the basic system design of SMART. In order to establish and optimize the basic system design of SMART, the basis of selection for the valve operator type were provided based on the basic design requirements. The basis of valve operator selection for SMART will be used as a basic technical data for the SMART basic and detail design and a fundamental material for the new reactor development in the future

  13. Basis of valve operator selection for SMART

    Energy Technology Data Exchange (ETDEWEB)

    Kang, H. S.; Lee, D. J.; See, J. K.; Park, C. K.; Choi, B. S

    2000-05-01

    SMART, an integral reactor with enhanced safety and operability, is under development for use of the nuclear energy. The valve operator of SMART system were selected through the data survey and technical review of potential valve fabrication vendors, and it will provide the establishment and optimization of the basic system design of SMART. In order to establish and optimize the basic system design of SMART, the basis of selection for the valve operator type were provided based on the basic design requirements. The basis of valve operator selection for SMART will be used as a basic technical data for the SMART basic and detail design and a fundamental material for the new reactor development in the future.

  14. Orthogonal Basis Spreading Sequence for Optimal CDMA

    OpenAIRE

    Tsuda, Hirofumi; Umeno, Ken

    2016-01-01

    Recently, new spreading sequences have been proposed to multiplex the capacity of users. In particular, Weyl spreading sequences have the larger capacity of users than Gold code. This paper shows that Weyl spreading sequences appear in bit restoring model and they are orthogonal basis in the particular situation. This result shows the reason why they have the large capacity and that any spreading sequence are expressed as the sum of Weyl spreading sequences.

  15. The neural basis of tactile motion perception

    OpenAIRE

    Pei, Yu-Cheng; Sliman J Bensmaia

    2014-01-01

    The manipulation of objects commonly involves motion between object and skin. In this review, we discuss the neural basis of tactile motion perception and its similarities with its visual counterpart. First, much like in vision, the perception of tactile motion relies on the processing of spatiotemporal patterns of activation across populations of sensory receptors. Second, many neurons in primary somatosensory cortex are highly sensitive to motion direction, and the response properties of th...

  16. Conceptual basis for the european sustainability footprint

    OpenAIRE

    PELLETIER NATHANIEL; Maas, Rob; GORALCZYK MALGORZATA; WOLF Marc-Andree

    2012-01-01

    Sustainability is central to the policy objectives of the European Commission (EC), but a widely accepted integrated sustainability assessment framework in support of policy analysis and development is currently lacking. Here, we describe the conceptual basis for the proposed European Sustainability Footprint (ESF) - an integrated sustainability assessment framework for establishing a baseline and tracking trends with respect to the sustainability of European production and consumption. This ...

  17. Neurons with radial basis like rate functions.

    Science.gov (United States)

    Kovács, Zsolt László

    2005-01-01

    Artificial neural networks constructed with "locally tuned processing units" and more generally referred to as "radial basis function networks" have been proposed by a number of workers. In this communication, I submit a conjecture, based on indirect experimental and direct computational evidence of the Hodgkin-Huxley model, that there may be biological neurons in nervous systems for which the rate function is locally tuned. If proved to be valid, this conjecture may simplify neurodynamic models of some functions of nervous systems.

  18. Texture Zeros and Weak Basis Transformations

    CERN Document Server

    Branco, Gustavo Castello; Felipe, R G

    2000-01-01

    We investigate the physical meaning of some of the "texture zeros" which appear in most of the Ansatze on quark masses and mixings. It is shown that starting from arbitrary quark mass matrices and making a suitable weak basis transformation one can obtain some of these sets of zeros which therefore have no physical content. We then analyse the physical implications of a four-texture zero Ansatz which is in agreement with all present experimental data.

  19. A Genetic Basis for Motivated Exercise.

    Science.gov (United States)

    Good, Deborah J; Li, Mengjiao; Deater-Deckard, Kirby

    2015-10-01

    Prior research has demonstrated a genetic basis for motivated exercise, with evidence of a role for nescient helix-loop-helix-2 (NHLH2/Nhlh2). Nhlh2 transcriptionally regulates the monoamine oxidase A (MAO-A) gene. This article examines the evidence for the hypothesis that polymorphisms in NHLH2 or MAO-A contribute to differences in the human motivation for exercise and physical activity. The genetic pathways that link exercise and motivation are discussed.

  20. The neural basis of bounded rational behavior

    OpenAIRE

    Coricelli, Giorgio; Nagel, Rosemarie

    2010-01-01

    Bounded rational behaviour is commonly observed in experimental games and in real life situations. Neuroeconomics can help to understand the mental processing underlying bounded rationality and out-of-equilibrium behaviour. Here we report results from recent studies on the neural basis of limited steps of reasoning in a competitive setting —the beauty contest game. We use functional magnetic resonance imaging (fMRI) to study the neural correlates of human mental processes in strategic games. ...

  1. PROPRIOCEPTION AS A BASIS FOR INDIVIDUAL DIFFERENCES

    OpenAIRE

    Liutsko, Liudmila

    2013-01-01

    In this chapter the author summarises the descriptions of proprioceptive sense from different perspectives. The importance of proprioceptive sense has been shown in developmental psychology, in both the earlier and later stages of individuum formation. The author emphasises in this chapter the role of proprioception as a basis of personality and the individual differences construct. The importance of assessing behaviour at multiple levels has been pointed out by experiments of classic and mod...

  2. PEDAGOGICAL AND PSYHOLOGICAL BASIS OF MORAL EDUCATION

    OpenAIRE

    Aneta Barakoska; Aneta Jovkovska

    2013-01-01

    Analyses of pedagogical and psychological literature show that education and upbringing are oriented to nursing moral values. In pedagogy’s historical context, the most important goals are education, development, and self-development of life experience and student’s perception of efforts to build values in their own life.In different historical periods, different moral values appear in the society. They are united by being directed towards humanism and on the basis of personal experience they...

  3. Optical implementations of radial basis classifiers

    OpenAIRE

    Neifeld, Mark A.; Psaltis, Demetri

    1993-01-01

    We describe two optical systems based on the radial basis function approach to pattern classification. An optical-disk-based system for handwritten character recognition is demonstrated. The optical system computes the Euclidean distance between an unknown input and 650 stored patterns at a demonstrated rate of 26,000 pattern comparisons/s. The ultimate performance of this system is limited by optical-disk resolution to 10^11 binary operations/s. An adaptive system is also presented that faci...

  4. Nearest lattice point algorithms on semi k-reduced basis

    Institute of Scientific and Technical Information of China (English)

    阚海斌; 沈鸿

    2003-01-01

    In this paper, we firstly generalize the relations among the basis vectors of LLL reduced basis to semi k-reduced basis. Then we analyze the complexities of the nearest plane algorithm and round-off algorithm on semi k-reduced basis, which, compared with L. Babai's results on LLL reduced basis, have better approximate ratios and contain almost the same time complexities.

  5. Calibration of options on a reduced basis

    Science.gov (United States)

    Pironneau, Olivier

    2009-10-01

    Calibration of models is an important step in financial engineering. However it can be costly, especially in view of the increasing complexity of the models. In this paper we explore the use of reduced basis as is done in fluid mechanics for the Navier-Stokes equations or as proposed by Maday, Patera and Turinici [Y. Maday et al., A priori convergence theory for reduced-basis approximations of single-parameter elliptic partial differential equations, J. Sci. Comput. 17 (1-4) (2002) 437-446]. It is shown that the method works well if we use convex combination of the basis functions instead of the more general linear combination; however, while this idea makes sense in view of the properties of the Black-Scholes equation, we have no proof to general linear combination; however, while this idea makes sense in view of the properties of the Black-Scholes equation, we have no proof to justify it mathematically. The paper presents a numerical investigation of the problem posed.

  6. The Teleological Resocialization: theoretical-praxeological basis

    Directory of Open Access Journals (Sweden)

    Sławomir Sobczak

    2011-12-01

    Full Text Available Resocialization and Social Prevention is a theoretical and a praxeological subject, thus teleology of resocialization as its building block should relate both to its theoretical and practical aspects, i.e. to goals and postulates formed on the basis of paradigms and diagnosis. In the article are pointed out the reasons for forming teleology of resocialization due to the foundation of fundamental thinking, i.e. monistic basis (idealism, materialism and pluralism (realism and also the outcomes of making presumptions in aspects of the process of planning deliberate actions. On one hand the modern praxeology points to forming the goals of the treatment in the phase of equifinality on the basis of the diagnosis as an information on the system, on the other hand the theoretical aspect of resocialization teleology is described imprecisely, from only one angle. In resocialization teleology there is a narrowing to idealistic or material thinking, which considers axiology as the foundation of forming goals, according to their way of thinking. Having a particular way of thinking is not a mistake. It is, however, a mistake to inform the reader in books that this way of thinking is the only way, though not too suitable, but having no alternative. In the available literature on the subject both the axiological and anthropological bases of teleology are formed. Therefore, neither the axiology nor anthropology should be mentioned as an equivalent to teleology, instead the teleology as a knowledge can only be based on either the axiology or anthropology.

  7. Accurate basis set truncation for wavefunction embedding

    Science.gov (United States)

    Barnes, Taylor A.; Goodpaster, Jason D.; Manby, Frederick R.; Miller, Thomas F.

    2013-07-01

    Density functional theory (DFT) provides a formally exact framework for performing embedded subsystem electronic structure calculations, including DFT-in-DFT and wavefunction theory-in-DFT descriptions. In the interest of efficiency, it is desirable to truncate the atomic orbital basis set in which the subsystem calculation is performed, thus avoiding high-order scaling with respect to the size of the MO virtual space. In this study, we extend a recently introduced projection-based embedding method [F. R. Manby, M. Stella, J. D. Goodpaster, and T. F. Miller III, J. Chem. Theory Comput. 8, 2564 (2012)], 10.1021/ct300544e to allow for the systematic and accurate truncation of the embedded subsystem basis set. The approach is applied to both covalently and non-covalently bound test cases, including water clusters and polypeptide chains, and it is demonstrated that errors associated with basis set truncation are controllable to well within chemical accuracy. Furthermore, we show that this approach allows for switching between accurate projection-based embedding and DFT embedding with approximate kinetic energy (KE) functionals; in this sense, the approach provides a means of systematically improving upon the use of approximate KE functionals in DFT embedding.

  8. ¿CÓMO SE TRADUCE EL CURRICULUM FORMAL EN UNA EXPERIENCIA ESCOLAR RELEVANTE PARA LOS ALUMNOS DE UNA ESCUELA TELESECUNDARIA DE MÉXICO? (HOW DO THE STUDENTS OF A TELESECONDARY SCHOOL IN MEXICO TRANSLATE THE FORMAL CURRICULUM IN A RELEVANT SCHOOL EXPERIENCE?

    Directory of Open Access Journals (Sweden)

    Sánchez Tepatzi José de la luz

    2011-08-01

    Full Text Available Resumen:En este artículo se presenta parte de los resultados obtenidos en una investigación realizada entre los años 2009 y 2010 en una comunidad rural en México donde participaron 12 personas que abandonaron la escuela tele-secundaria. El estudio es de tipo cualitativo y las principales herramientas para obtener la información fueron la historia de vida y la entrevista abierta. La pregunta que orienta este artículo analiza las formas en cómo los alumnos traducen el curriculum formal en una experiencia escolar relevante y cómo influye tal significado en la permanencia. Los principales resultados señalan que la relación profesor-alumno, el trato entre pares y el apoyo de la familia, son elementos importantes para mejorar la permanencia y la calidad de los aprendizajes, así como para otorgar significado relevante a esa experiencia. En las conclusiones del estudio se muestra que el valor positivo hacia la escuela y la relevancia de la experiencia escolar, no son elementos suficientes para garantizar la permanencia, pues en esa decisión intervienen otros factores y razonamientos particulares. Es decir, cada alumno, en su mundo de vida construye un sentido de la realidad y este es el que orienta sus decisiones; una de ellas es permanecer o retirarse de la escuela. En este marco de relativa autonomía, los profesores estamos obligados a ofrecer a los alumnos la oportunidad de vivir una experiencia escolar relevante que les permita desenvolverse en un mundo complejo y aprender a lo largo de la vida, más allá de su condición y disposición para permanecer en la escuela.Abstract: This article I share part of the results of an investigation developed during the 2009 and 2010 year in a rural community in Mexico. In this study participated 12 persons who left school tele-secondary. The study is qualitative and the main methodological tools were the history of life and the open interview. The question that guides this research, it examines the

  9. An orthogonal basis for the hyperbolic hybrid polynomial space

    Institute of Scientific and Technical Information of China (English)

    HUANG Yu; WANG GuoZhao

    2007-01-01

    Motivated by the wide usage of the Tchebyshev basis and Legendre basis in the algebra polynomial space, we construct an orthogonal basis with the properties of the H-Bézier basis in the hyperbolic hybrid polynomial space, which is similar to the Legendre basis and holds remarkable properties. Moreover, we derive the transformation matrices that map the H-Bézier basis and the orthogonal basis forms into each other. An example for approximating the degree reduction of the H- Bézier curves is sketched to illustrate the utility of the orthogonal basis.

  10. Technical basis for internal dosimetry at Hanford

    Energy Technology Data Exchange (ETDEWEB)

    Sula, M.J.; Carbaugh, E.H.; Bihl, D.E.

    1989-04-01

    The Hanford Internal Dosimetry Program, administered by Pacific Northwest Laboratory for the US Department of Energy, provides routine bioassay monitoring for employees who are potentially exposed to radionuclides in the workplace. This report presents the technical basis for routine bioassay monitoring and the assessment of internal dose at Hanford. The radionuclides of concern include tritium, corrosion products (/sup 58/Co, /sup 60/Co, /sup 54/Mn, and /sup 59/Fe), strontium, cesium, iodine, europium, uranium, plutonium, and americium. Sections on each of these radionuclides discuss the sources and characteristics; dosimetry; bioassay measurements and monitoring; dose measurement, assessment, and mitigation; and bioassay follow-up treatment. 64 refs., 42 figs., 118 tabs.

  11. Technical basis for internal dosimetry at Hanford

    Energy Technology Data Exchange (ETDEWEB)

    Sula, M.J.; Carbaugh, E.H.; Bihl, D.E.

    1991-07-01

    The Hanford Internal Dosimetry Program, administered by Pacific Northwest Laboratory for the US Department of Energy, provides routine bioassay monitoring for employees who are potentially exposed to radionuclides in the workplace. This report presents the technical basis for routine bioassay monitoring and the assessment of internal dose at Hanford. The radionuclides of concern include tritium, corrosion products ({sup 58}Co, {sup 60}Co, {sup 54}Mn, and {sup 59}Fe), strontium, cesium, iodine, europium, uranium, plutonium, and americium,. Sections on each of these radionuclides discuss the sources and characteristics; dosimetry; bioassay measurements and monitoring; dose measurement, assessment, and mitigation and bioassay follow-up treatment. 78 refs., 35 figs., 115 tabs.

  12. Conductance calculations with a wavelet basis set

    DEFF Research Database (Denmark)

    Thygesen, Kristian Sommer; Bollinger, Mikkel; Jacobsen, Karsten Wedel

    2003-01-01

    We present a method based on density functional theory (DFT) for calculating the conductance of a phase-coherent system. The metallic contacts and the central region where the electron scattering occurs, are treated on the same footing taking their full atomic and electronic structure into account....... The linear-response conductance is calculated from the Green's function which is represented in terms of a system-independent basis set containing wavelets with compact support. This allows us to rigorously separate the central region from the contacts and to test for convergence in a systematic way...

  13. Central waste complex interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    Cain, F.G.

    1995-05-15

    This interim safety basis provides the necessary information to conclude that hazards at the Central Waste Complex are controlled and that current and planned activities at the CWC can be conducted safely. CWC is a multi-facility complex within the Solid Waste Management Complex that receives and stores most of the solid wastes generated and received at the Hanford Site. The solid wastes that will be handled at CWC include both currently stored and newly generated low-level waste, low-level mixed waste, contact-handled transuranic, and contact-handled TRU mixed waste.

  14. Tests for Wavelets as a Basis Set

    Science.gov (United States)

    Baker, Thomas; Evenbly, Glen; White, Steven

    A wavelet transformation is a special type of filter usually reserved for image processing and other applications. We develop metrics to evaluate wavelets for general problems on test one-dimensional systems. The goal is to eventually use a wavelet basis in electronic structure calculations. We compare a variety of orthogonal wavelets such as coiflets, symlets, and daubechies wavelets. We also evaluate a new type of orthogonal wavelet with dilation factor three which is both symmetric and compact in real space. This work was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under Award #DE-SC008696.

  15. Beyond design basis issues in China

    International Nuclear Information System (INIS)

    In China, SSCs covered by the AMP for LTO are screened based on the principles spelled out in an IAEA publication (see Ref. [9]). Only key SSCs are selected and included in the scope of the AMP for LTO. The vast majority of the SSCs beyond those included in the scope of the AMP are managed by the general maintenance plan. Although lessons learned from the Fukushima Daiichi accident may have a limited impact on the AMP for LTO, there are some challenges originating from the analysis of events beyond design basis, especially external events, that will dictate some specific ageing programmes not previously included in the AMP

  16. Reduced Basis Method for Nanodevices Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Pau, George Shu Heng

    2008-05-23

    Ballistic transport simulation in nanodevices, which involves self-consistently solving a coupled Schrodinger-Poisson system of equations, is usually computationally intensive. Here, we propose coupling the reduced basis method with the subband decomposition method to improve the overall efficiency of the simulation. By exploiting a posteriori error estimation procedure and greedy sampling algorithm, we are able to design an algorithm where the computational cost is reduced significantly. In addition, the computational cost only grows marginally with the number of grid points in the confined direction.

  17. Study on Physical Basis of Cold Fusion

    Institute of Scientific and Technical Information of China (English)

    李家全; 沈丽如; 李国盛; 李炯

    2002-01-01

    In order to understand questions about the study on cold fusion in these years, we have studied physical basis of cold fusion. Results show that even though the cold fusion is feasible theoretically in the view of physics, but its reaction ratio is too small to be detected, so that it has no prospect for practical usage at present. However, in order to tackle urgent problem of being poor in energy resources, we have no choice but to pay more attention to controlled thermal nuclear fusion in a considerably long period of time.

  18. Technical basis for internal dosimetry at Hanford

    International Nuclear Information System (INIS)

    The Hanford Internal Dosimetry Program, administered by Pacific Northwest Laboratory for the US Department of Energy, provides routine bioassay monitoring for employees who are potentially exposed to radionuclides in the workplace. This report presents the technical basis for routine bioassay monitoring and the assessment of internal dose at Hanford. The radionuclides of concern include tritium, corrosion products (58Co, 60Co, 54Mn, and 59Fe), strontium, cesium, iodine, europium, uranium, plutonium, and americium. Sections on each of these radionuclides discuss the sources and characteristics; dosimetry; bioassay measurements and monitoring; dose measurement, assessment, and mitigation; and bioassay follow-up treatment. 64 refs., 42 figs., 118 tabs

  19. Scientific basis of investing agrarian sphere

    Directory of Open Access Journals (Sweden)

    Novak I. M.

    2015-05-01

    Full Text Available The article deals with the scientific basis of investing agrarian economy of Ukraine. The emphasis is on the nature of the investment, the investment climate and the attractiveness of the agricultural sector. It is specified on the relevance of developing effective investment strategies for agricultural sector. It is proved that the creation of favorable conditions for investors improves the work of the financial system in the country. The factors that form and affect the investment climate are studied. Measures, aimed at disclosing and strengthening of investment potential of country are proposed.

  20. Neurobiological Basis of Language Learning Difficulties.

    Science.gov (United States)

    Krishnan, Saloni; Watkins, Kate E; Bishop, Dorothy V M

    2016-09-01

    In this paper we highlight why there is a need to examine subcortical learning systems in children with language impairment and dyslexia, rather than focusing solely on cortical areas relevant for language. First, behavioural studies find that children with these neurodevelopmental disorders perform less well than peers on procedural learning tasks that depend on corticostriatal learning circuits. Second, fMRI studies in neurotypical adults implicate corticostriatal and hippocampal systems in language learning. Finally, structural and functional abnormalities are seen in the striatum in children with language disorders. Studying corticostriatal networks in developmental language disorders could offer us insights into their neurobiological basis and elucidate possible modes of compensation for intervention. PMID:27422443

  1. Thermodynamic basis of site-specific cooperativity.

    Science.gov (United States)

    Di Cera, E

    1994-08-01

    Cooperative phenomena in biological macromolecules arise from the interaction of many distinct subsystems, such as structural domains or binding sites. Cooperative properties of the system as a whole, like protein folding or allosteric transitions, are subject to the restrictions imposed by thermodynamic stability. These restrictions, however, do not apply in the case of individual subsystems open to interactions with the rest of the macromolecule. The site-specific properties of such subsystems can be understood in general thermodynamic terms from those of a multicomponent system under particular conditions. The analogy provides a thermodynamic basis for site-specific cooperativity. PMID:8075382

  2. Anatomical basis for Wilms tumor surgery

    Directory of Open Access Journals (Sweden)

    Trobs R

    2009-01-01

    Full Text Available Wilms tumor surgery requires meticulous planning and sophisticated surgical technique. Detailed anatomical knowledge can facilitate the uneventful performance of tumor nephrectomy and cannot be replaced by advanced and sophisticated imaging techniques. We can define two main goals for surgery: (1 exact staging as well as (2 safe and complete resection of tumor without spillage. This review aims to review the anatomical basis for Wilms tumor surgery. It focuses on the surgical anatomy of retroperitoneal space, aorta, vena cava and their large branches with lymphatics. Types and management of vascular injuries are discussed.

  3. The Cellular Basis of a Corollary Discharge

    Science.gov (United States)

    Poulet, James F. A.; Hedwig, Berthold

    2006-01-01

    How do animals discriminate self-generated from external stimuli during behavior and prevent desensitization of their sensory pathways? A fundamental concept in neuroscience states that neural signals, termed corollary discharges or efference copies, are forwarded from motor to sensory areas. Neurons mediating these signals have proved difficult to identify. We show that a single, multisegmental interneuron is responsible for the pre- and postsynaptic inhibition of auditory neurons in singing crickets (Gryllus bimaculatus). Therefore, this neuron represents a corollary discharge interneuron that provides a neuronal basis for the central control of sensory responses.

  4. Scientific basis for nuclear waste management XVII

    International Nuclear Information System (INIS)

    The 17th Materials Research Society Symposium on the Scientific Basis for Nuclear Waste Management included 17 sessions, during which 120 papers were presented by scientists from 16 countries. The nuclear waste glass overview surveyed achievements to date and identified issues requiring further research. The objectives and limitations session noted the progress that has been made in developing a scientific basis for nuclear waste management, but questioned whether regulations calling for detailed predictions over a period of 10,000 years are either necessary or capable of being satisfied. The other papers presented at the Symposium described the progress of studies in a broad array of areas of nuclear waste science and technology. These areas included radiation effects and gas generation, ceramic materials, cementitious materials, actinides spent fuel, glass processing and properties, glass leaching, dissolution and alteration, natural and ancient analogues, transuranic wastes and special topics, sorption mechanisms, repository studies, geochemistry and hydrology, containers, and backfill materials. Several novel experimental techniques were described, as well as advances in modeling. An encouraging feature of the progress in modeling is that the agreement between calculated results based on models developed, refined and tested in the US and in other countries on one hand, and experimental data on the other, shows considerable improvement. This reflects greater understanding of the mechanisms involved in the release of radionuclides from the various components of the waste repository system, including the wasteforms themselves. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database

  5. Spherical radial basis functions, theory and applications

    CERN Document Server

    Hubbert, Simon; Morton, Tanya M

    2015-01-01

    This book is the first to be devoted to the theory and applications of spherical (radial) basis functions (SBFs), which is rapidly emerging as one of the most promising techniques for solving problems where approximations are needed on the surface of a sphere. The aim of the book is to provide enough theoretical and practical details for the reader to be able to implement the SBF methods to solve real world problems. The authors stress the close connection between the theory of SBFs and that of the more well-known family of radial basis functions (RBFs), which are well-established tools for solving approximation theory problems on more general domains. The unique solvability of the SBF interpolation method for data fitting problems is established and an in-depth investigation of its accuracy is provided. Two chapters are devoted to partial differential equations (PDEs). One deals with the practical implementation of an SBF-based solution to an elliptic PDE and another which describes an SBF approach for solvi...

  6. Technical Basis for PNNL Beryllium Inventory

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Michelle Lynn

    2014-07-09

    The Department of Energy (DOE) issued Title 10 of the Code of Federal Regulations Part 850, “Chronic Beryllium Disease Prevention Program” (the Beryllium Rule) in 1999 and required full compliance by no later than January 7, 2002. The Beryllium Rule requires the development of a baseline beryllium inventory of the locations of beryllium operations and other locations of potential beryllium contamination at DOE facilities. The baseline beryllium inventory is also required to identify workers exposed or potentially exposed to beryllium at those locations. Prior to DOE issuing 10 CFR 850, Pacific Northwest Nuclear Laboratory (PNNL) had documented the beryllium characterization and worker exposure potential for multiple facilities in compliance with DOE’s 1997 Notice 440.1, “Interim Chronic Beryllium Disease.” After DOE’s issuance of 10 CFR 850, PNNL developed an implementation plan to be compliant by 2002. In 2014, an internal self-assessment (ITS #E-00748) of PNNL’s Chronic Beryllium Disease Prevention Program (CBDPP) identified several deficiencies. One deficiency is that the technical basis for establishing the baseline beryllium inventory when the Beryllium Rule was implemented was either not documented or not retrievable. In addition, the beryllium inventory itself had not been adequately documented and maintained since PNNL established its own CBDPP, separate from Hanford Site’s program. This document reconstructs PNNL’s baseline beryllium inventory as it would have existed when it achieved compliance with the Beryllium Rule in 2001 and provides the technical basis for the baseline beryllium inventory.

  7. Basis for calculations in the topological expansion

    International Nuclear Information System (INIS)

    Investigations aimed at putting the topological theory of particles on a more quantitative basis are described. First, the incorporation of spin into the topological structure is discussed and shown to successfully reproduce the observed lowest mass hadron spectrum. The absence of parity-doubled states represents a significant improvement over previous efforts in similar directions. This theory is applied to the lowest order calculation of elementary hadron coupling constant ratios. SU(6)/sub W/ symmetry is maintained and extended via the notions of topological supersymmetry and universality. Finally, efforts to discover a perturbative basis for the topological expansion are described. This has led to the formulation of off-shell Feynman-like rules which provide a calculational scheme for the strong interaction components of the topological expansion once the zero-entropy connected parts are known. These rules are shown to imply a topological asymptotic freedom. Even though the nonlinear zero-entropy problem cannot itself be treated perturbatively, plausible general assumptions about zero-entropy amplitudes allow immediate qualitative inferences concerning physical hadrons. In particular, scenarios for mass splittings beyond the supersymmetric level are described

  8. Modelling erosion on a daily basis

    Science.gov (United States)

    Pikha Shrestha, Dhruba; Jetten, Victor

    2016-04-01

    Effect of soil erosion causing negative impact on ecosystem services and food security is well known. To assess annual erosion rates various empirical models have been extensively used in all the climatic regions. While these models are simple to operate and do not require lot of input data, the effect of extreme rain is not taken into account in the annual estimations. For analysing the effects of extreme rain the event- based models become handy. These models can simulate detail erosional processes including particle detachment, transportation and deposition of sediments during a storm. But they are not applicable for estimating annual erosion rates. Moreover storm event data may not be available everywhere which prohibits their extensive use. In this paper we describe a method by adapting the revised MMF model to assess erosion on daily basis so that the effects of extreme rains are taken into account. We couple it to a simple surface soil moisture balance on a daily basis and include estimation of daily vegetation cover changes. Annual soil loss is calculated by adding daily erosion rates. We compare the obtained results with that obtained from applying the revised MMF model in a case study in the Mamora plateau in northwest Morocco which is affected by severe gully formation. The results show clearly the effects of exceptional rain in erosional processes which cannot be captured in an annual model.

  9. A Scientific Basis for Climate Policy

    International Nuclear Information System (INIS)

    The Scientific Council on Climate Issues has been commissioned by the Swedish Government to provide a scientific assessment as a basis for the work of the Climate Committee, the all-party committee for the review of climate policy. An important part of this task is to provide a basis and recommendations for Swedish climate policy targets at national, EU and international level. In the opening chapters, the Council looks at climate change, its reasons and its consequences for ecosystems and society. The Council then makes recommendations concerning Swedish climate policy targets at global, EU and national levels, aimed at averting dangerous impact on the climate. In the concluding chapters, the Council presents a number of possible measures and policy instruments, and outlines the likely costs involved if the goals are to be achieved. Taken as a whole, the document represents a comprehensive basis for policy decisions that consider what needs to be achieved to reduce the risks of climate impact and what is actually achievable, i.e. decisions involving trade-offs between economic benefits and costs. The Council considers: that the EU's GHG emissions compared to the 1990 level should be reduced by 30-40 % by 2020 and by 75-90 % by 2050 if the Union is to take its share of the global responsibility for achievement of the two-degree target; that Sweden's GHG emissions compared to the 1990 level should be reduced by 20-25 % by 2020 and by 70-85 % by 2050 if Sweden is to take its share of the global responsibility for achievement of the two-degree target; that a national emission target for Sweden should be formulated as a target with deductible emissions allowances, i.e., that assessment of target achievement is based on the amount of emission allowances allocated or auctioned by Sweden to activities covered by the EU emissions trading scheme rather than the actual volume of emissions from these activities. The Council has provided an overview of possible measures for

  10. 14 CFR 152.315 - Reporting on accrual basis.

    Science.gov (United States)

    2010-01-01

    ...) AIRPORTS AIRPORT AID PROGRAM Accounting and Reporting Requirements § 152.315 Reporting on accrual basis. (a... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Reporting on accrual basis. 152.315 Section... financial reports on an accrual basis. (b) If records are not maintained on an accrual basis by a sponsor...

  11. Nuclear energy - basis for hydrogen economy

    International Nuclear Information System (INIS)

    The development of human civilization in general as well as that of every country in particular is in direct relation to the assurance of a cost effective energy balance encompassing all industrial spheres and everyday activities. Unfortunately, the uncontrolled utilization of Earth's energy resources is already causing irreversible damage to various components of the eco-system of the Earth. Nuclear energy used for electricity and hydrogen production has the biggest technological potential for solving of the main energy outstanding issues of the new century: increasing of energy dependence; global warming. Because of good market position the political basis is assured for fast development of new generation nuclear reactors and fuel cycles which can satisfy vigorously increasing needs of affordable and clean energy. Political conditions are created for adequate participation of nuclear energy in the future global energy mix. They must give chance to the nuclear industry to take adequate part in the new energy generation capacity.(author)

  12. Mentoring as the basis for social business

    Directory of Open Access Journals (Sweden)

    Artcer Tatiana

    2016-01-01

    Full Text Available In this article the concept of mentoring as a basis for social business is considered. Besides, the ways of increase of efficiency of labor use through the institute of mentoring of young workers are considered by elderly people. Features of employment, work and dismissal of aging employees are also considered. Possibilities of application of mentoring, attraction of experience of pensioners taking into account the high level of their qualification are reflected. Tasks which the institute of mentoring will help to solve are formulated. The article examines the possibility of using mentoring and engaging retired employees with their experience, a high level of their education and professional qualification in the training of young inexperienced workers. Mentoring is presented as an element of social entrepreneurship.

  13. Technical basis document for internal dosimetry

    CERN Document Server

    Hickman, D P

    1991-01-01

    This document provides the technical basis for the Chem-Nuclear Geotech (Geotech) internal dosimetry program. Geotech policy describes the intentions of the company in complying with radiation protection standards and the as low as reasonably achievable (ALARA) program. It uses this policy and applicable protection standards to derive acceptable methods and levels of bioassay to assure compliance. The models and computational methods used are described in detail within this document. FR-om these models, dose- conversion factors and derived limits are computed. These computations are then verified using existing documentation and verification information or by demonstration of the calculations used to obtain the dose-conversion factors and derived limits. Recommendations for methods of optimizing the internal dosimetry program to provide effective monitoring and dose assessment for workers are provided in the last section of this document. This document is intended to be used in establishing an accredited dosi...

  14. Prototype Hanford Surface Barrier: Design basis document

    International Nuclear Information System (INIS)

    The Hanford Site Surface Barrier Development Program (BDP) was organized in 1985 to develop the technology needed to provide a long-term surface barrier capability for the Hanford Site and other arid sites. This document provides the basis of the prototype barrier. Engineers and scientists have momentarily frozen evolving barrier designs and incorporated the latest findings from BDP tasks. The design and construction of the prototype barrier has required that all of the various components of the barrier be brought together into an integrated system. This integration is particularly important because some of the components of the protective barreir have been developed independently of other barreir components. This document serves as the baseline by which future modifications or other barrier designs can be compared. Also, this document contains the minutes of meeting convened during the definitive design process in which critical decisions affecting the prototype barrier's design were made and the construction drawings

  15. Generalization performance of radial basis function networks.

    Science.gov (United States)

    Lei, Yunwen; Ding, Lixin; Zhang, Wensheng

    2015-03-01

    This paper studies the generalization performance of radial basis function (RBF) networks using local Rademacher complexities. We propose a general result on controlling local Rademacher complexities with the L1 -metric capacity. We then apply this result to estimate the RBF networks' complexities, based on which a novel estimation error bound is obtained. An effective approximation error bound is also derived by carefully investigating the Hölder continuity of the lp loss function's derivative. Furthermore, it is demonstrated that the RBF network minimizing an appropriately constructed structural risk admits a significantly better learning rate when compared with the existing results. An empirical study is also performed to justify the application of our structural risk in model selection.

  16. Basis Function Sampling for Material Property Computations

    Science.gov (United States)

    Whitmer, Jonathan K.; Chiu, Chi-Cheng; Joshi, Abhijeet A.; de Pablo, Juan J.

    2014-03-01

    Wang-Landau sampling, and the associated class of flat histogram simulation methods, have been particularly successful for free energy calculations in a wide array of physical systems. Practically, the convergence of these calculations to a target free energy surface is hampered by reliance on parameters which are unknown a priori. We derive and implement a method based on orthogonal (basis) functions which is fast, parameter-free, and geometrically robust. An important feature of this method is its ability to achieve arbitrary levels of description for the free energy. It is thus ideally suited to in silico measurement of elastic moduli and other quantities related to free energy perturbations. We demonstrate the utility of such applications by applying our method to calculation of the Frank elastic constants of the Lebwohl-Lasher model.

  17. A logical basis for constructive systems

    CERN Document Server

    Japaridze, Giorgi

    2010-01-01

    The work is devoted to Computability Logic (CoL) -- the philosophical/mathematical platform and long-term project for redeveloping classical logic after replacing truth} by computability in its underlying semantics (see http://www.cis.upenn.edu/~giorgi/cl.html). This article elaborates some basic complexity theory for the CoL framework. Then it proves soundness and completeness for the deductive system CL12 with respect to the semantics of CoL, including the version of the latter based on polynomial time computability instead of computability-in-principle. CL12 is a sequent calculus system, where the meaning of a sequent intuitively can be characterized as "the succedent is algorithmically reducible to the antecedent", and where formulas are built from predicate letters, function letters, variables, constants, identity, negation, parallel and choice connectives, and blind and choice quantifiers. A case is made that CL12 is an adequate logical basis for constructive applied theories, including complexity-orien...

  18. Flexible Bit Preservation on a National Basis

    DEFF Research Database (Denmark)

    Jurik, Bolette; Nielsen, Anders Bo; Zierau, Eld

    2012-01-01

    In this paper we present the results from The Danish National Bit Repository project. The project aim was establishment of a system that can offer flexible and sustainable bit preservation solutions to Danish cultural heritage institutions. Here the bit preservation solutions must include support...... of bit safety as well as other requirements like e.g. confidentiality and availability. The Danish National Bit Repository is motivated by the need to investigate and handle bit preservation for digital cultural heritage. Digital preservation relies on the integrity of the bits which digital material...... consists of, and it is with this focus that the project was initiated. This paper summarizes the requirements for a general system to offer bit preservation to cultural heritage institutions. On this basis the paper describes the resulting flexible system which can support such requirements. The paper...

  19. Physiologic basis for understanding quantitative dehydration assessment.

    Science.gov (United States)

    Cheuvront, Samuel N; Kenefick, Robert W; Charkoudian, Nisha; Sawka, Michael N

    2013-03-01

    Dehydration (body water deficit) is a physiologic state that can have profound implications for human health and performance. Unfortunately, dehydration can be difficult to assess, and there is no single, universal gold standard for decision making. In this article, we review the physiologic basis for understanding quantitative dehydration assessment. We highlight how phenomenologic interpretations of dehydration depend critically on the type (dehydration compared with volume depletion) and magnitude (moderate compared with severe) of dehydration, which in turn influence the osmotic (plasma osmolality) and blood volume-dependent compensatory thresholds for antidiuretic and thirst responses. In particular, we review new findings regarding the biological variation in osmotic responses to dehydration and discuss how this variation can help provide a quantitative and clinically relevant link between the physiology and phenomenology of dehydration. Practical measures with empirical thresholds are provided as a starting point for improving the practice of dehydration assessment.

  20. The molecular basis of hypertrophic scars.

    Science.gov (United States)

    Zhu, Zhensen; Ding, Jie; Tredget, Edward E

    2016-01-01

    Hypertrophic scars (HTS) are caused by dermal injuries such as trauma and burns to the deep dermis, which are red, raised, itchy and painful. They can cause cosmetic disfigurement or contractures if craniofacial areas or mobile region of the skin are affected. Abnormal wound healing with more extracellular matrix deposition than degradation will result in HTS formation. This review will introduce the physiology of wound healing, dermal HTS formation, treatment and difference with keloids in the skin, and it also review the current advance of molecular basis of HTS including the involvement of cytokines, growth factors, and macrophages via chemokine pathway, to bring insights for future prevention and treatment of HTS. PMID:27574672

  1. PEDAGOGICAL AND PSYHOLOGICAL BASIS OF MORAL EDUCATION

    Directory of Open Access Journals (Sweden)

    Aneta Barakoska

    2013-12-01

    Full Text Available Analyses of pedagogical and psychological literature show that education and upbringing are oriented to nursing moral values. In pedagogy’s historical context, the most important goals are education, development, and self-development of life experience and student’s perception of efforts to build values in their own life.In different historical periods, different moral values appear in the society. They are united by being directed towards humanism and on the basis of personal experience they represent completeness of general principles and norms of student’s behavior towards other people, nature, society and towards student’s themselves in the name of the common good. The already formed moral values have regulatory function in student’s life.The research problem is connected with humanization of the educational process.

  2. Attachment theory: a biological basis for psychotherapy?

    Science.gov (United States)

    Holmes, J

    1993-10-01

    John Bowlby bemoaned the separation between the biological and psychological approaches in psychiatry, and hoped that attachment theory, which brings together psychoanalysis and the science of ethology, would help bridge the rift between them. Recent findings in developmental psychology have delineated features of parent-infant interaction, especially responsiveness, attunement, and modulation of affect, which lead to either secure or insecure attachment. Similar principles can be applied to the relationship between psychotherapist and patient--the provision of a secure base, the emergence of a shared narrative ('autobiographical competence'), the processing of affect, coping with loss--these are common to most effective psychotherapies and provide the basis for a new interpersonal paradigm within psychotherapy. Attachment theory suggests they rest on a sound ethological and hence biological foundation.

  3. Measurement of photooxidants relevant to human biometeorology in an urban agglomeration (PHOTOX). Measurement of various hydrocarbons as precursors of photooxidants relevant to human biometeorology (KOVOX). Final report of Part 2; Erfassung von human-biometeorologisch relevanten Photooxidantien in einem Ballungsraum (PHOTOX). Erfassung verschiedener Kohlenwasserstoffe als Vorlaeufersubstanzen fuer human-biometeorologisch relevante Photooxidantien (KOVOX). Abschlussbericht zum Teil 2

    Energy Technology Data Exchange (ETDEWEB)

    Jakobi, G.; Fabian, P. [eds.

    1997-04-01

    The air-chemical components ozone and PAN (peroxy acetyl nitrate), their precursors NO and NO{sub 2} and the meteorological parameters air temperature, humidity, global radiation, wind direction and wind velocity were measured in the framework of a research project (PHOTOX - Measurement of photooxidants relevant to human biometeorology in an urban agglomeration) carried out by the Department of Bioclimatology and Pollution Research. Further, a wide range of anthropogenic and biogenic hydrocarbons, which are important groups of precursors of photooxidants and potential pollution factors, were measured in the framework of another research project (KOVOX - Measurement of various hydrocarbons as precursors of photooxidants relevant to human biometeorology). (orig/SR) [Deutsch] Die Messung der luftchemischen Komponenten Ozon und PAN (Peroxiacetylnitrat), deren Vorlaeufersubstanzen Stickstoffmonoxid (NO) und Stickstoffdioxid (NO{sub 2}) sowie deren meteorologischen Parameter Lufttemperatur, Luftfeuchtigkeit, Globalstrahlung, Windrichtung und Windgeschwindigkeit wurde im Rahmen des am Lehrstuhl fuer Bioklimatologie und Immisionsforschung laufenden Forschungsvorhabens ``Erfassung von human-biometeorologisch relevanten Photooxidantien in einem Ballungsraum (PHOTOX)`` durchgefuehrt. Des weiteren erfolgte die Messung einer breiten Palette anthropogener und biogener Kohlenwasserstoffe als wichtige Gruppen der Vorlaeufersubstanzen zur Photooxidantienbildung und moeglicher Wirkfaktoren, im Rahmen des Projektes ``Erfassung verschiedener Kohlenwasserstoffe als Vorlaeufersubstanzen fuer human-biometeorologisch relevante Photooxidantien (KOVOX)``. (orig./BW)

  4. The neural basis of human tool use.

    Science.gov (United States)

    Orban, Guy A; Caruana, Fausto

    2014-01-01

    In this review, we propose that the neural basis for the spontaneous, diversified human tool use is an area devoted to the execution and observation of tool actions, located in the left anterior supramarginal gyrus (aSMG). The aSMG activation elicited by observing tool use is typical of human subjects, as macaques show no similar activation, even after an extensive training to use tools. The execution of tool actions, as well as their observation, requires the convergence upon aSMG of inputs from different parts of the dorsal and ventral visual streams. Non-semantic features of the target object may be provided by the posterior parietal cortex (PPC) for tool-object interaction, paralleling the well-known PPC input to anterior intraparietal (AIP) for hand-object interaction. Semantic information regarding tool identity, and knowledge of the typical manner of handling the tool, could be provided by inferior and middle regions of the temporal lobe. Somatosensory feedback and technical reasoning, as well as motor and intentional constraints also play roles during the planning of tool actions and consequently their signals likewise converge upon aSMG. We further propose that aSMG may have arisen though duplication of monkey AIP and invasion of the duplicate area by afferents from PPC providing distinct signals depending on the kinematics of the manipulative action. This duplication may have occurred when Homo Habilis or Homo Erectus emerged, generating the Oldowan or Acheulean Industrial complexes respectively. Hence tool use may have emerged during hominid evolution between bipedalism and language. We conclude that humans have two parietal systems involved in tool behavior: a biological circuit for grasping objects, including tools, and an artifactual system devoted specifically to tool use. Only the latter allows humans to understand the causal relationship between tool use and obtaining the goal, and is likely to be the basis of all technological developments. PMID

  5. The neural basis of human tool use

    Directory of Open Access Journals (Sweden)

    Guy A Orban

    2014-04-01

    Full Text Available In this review, we propose that the neural basis for the spontaneous, diversified human tool use is an area devoted to the execution and observation of tool actions, located in the left anterior supramarginal gyrus (aSMG. The aSMG activation elicited by observing tool use is typical of human subjects, as macaques show no similar activation, even after an extensive training to use tools. The execution of tool actions, as well as their observation, requires the convergence upon aSMG of inputs from different parts of the dorsal and ventral visual streams. Non semantic features of the target object may be provided by the posterior parietal cortex (PPC for tool-object interaction, paralleling the well-known PPC input to AIP for hand-object interaction. Semantic information regarding tool identity, and knowledge of the typical manner of handling the tool, could be provided by inferior and middle regions of the temporal lobe. Somatosensory feedback and technical reasoning, as well as motor and intentional constraints also play roles during the planning of tool actions and consequently their signals likewise converge upon aSMG.We further propose that aSMG may have arisen though duplication of monkey AIP and invasion of the duplicate area by afferents from PPC providing distinct signals depending on the kinematics of the manipulative action. This duplication may have occurred when Homo Habilis or Homo Erectus emerged, generating the Oldowan or Acheulean Industrial complexes respectively. Hence tool use may have emerged during hominid evolution between bipedalism and language.We conclude that humans have two parietal systems involved in tool behavior: a biological circuit for grasping objects, including tools, and an artifactual system devoted specifically to tool use. Only the latter allows humans to understand the causal relationship between tool use and obtaining the goal, and is likely to be the basis of all technological developments.

  6. Many-Body Basis Set Superposition Effect.

    Science.gov (United States)

    Ouyang, John F; Bettens, Ryan P A

    2015-11-10

    The basis set superposition effect (BSSE) arises in electronic structure calculations of molecular clusters when questions relating to interactions between monomers within the larger cluster are asked. The binding energy, or total energy, of the cluster may be broken down into many smaller subcluster calculations and the energies of these subsystems linearly combined to, hopefully, produce the desired quantity of interest. Unfortunately, BSSE can plague these smaller fragment calculations. In this work, we carefully examine the major sources of error associated with reproducing the binding energy and total energy of a molecular cluster. In order to do so, we decompose these energies in terms of a many-body expansion (MBE), where a "body" here refers to the monomers that make up the cluster. In our analysis, we found it necessary to introduce something we designate here as a many-ghost many-body expansion (MGMBE). The work presented here produces some surprising results, but perhaps the most significant of all is that BSSE effects up to the order of truncation in a MBE of the total energy cancel exactly. In the case of the binding energy, the only BSSE correction terms remaining arise from the removal of the one-body monomer total energies. Nevertheless, our earlier work indicated that BSSE effects continued to remain in the total energy of the cluster up to very high truncation order in the MBE. We show in this work that the vast majority of these high-order many-body effects arise from BSSE associated with the one-body monomer total energies. Also, we found that, remarkably, the complete basis set limit values for the three-body and four-body interactions differed very little from that at the MP2/aug-cc-pVDZ level for the respective subclusters embedded within a larger cluster. PMID:26574311

  7. PREFACE: Progress in the ITER Physics Basis

    Science.gov (United States)

    Ikeda, K.

    2007-06-01

    I would firstly like to congratulate all who have contributed to the preparation of the `Progress in the ITER Physics Basis' (PIPB) on its publication and express my deep appreciation of the hard work and commitment of the many scientists involved. With the signing of the ITER Joint Implementing Agreement in November 2006, the ITER Members have now established the framework for construction of the project, and the ITER Organization has begun work at Cadarache. The review of recent progress in the physics basis for burning plasma experiments encompassed by the PIPB will be a valuable resource for the project and, in particular, for the current Design Review. The ITER design has been derived from a physics basis developed through experimental, modelling and theoretical work on the properties of tokamak plasmas and, in particular, on studies of burning plasma physics. The `ITER Physics Basis' (IPB), published in 1999, has been the reference for the projection methodologies for the design of ITER, but the IPB also highlighted several key issues which needed to be resolved to provide a robust basis for ITER operation. In the intervening period scientists of the ITER Participant Teams have addressed these issues intensively. The International Tokamak Physics Activity (ITPA) has provided an excellent forum for scientists involved in these studies, focusing their work on the high priority physics issues for ITER. Significant progress has been made in many of the issues identified in the IPB and this progress is discussed in depth in the PIPB. In this respect, the publication of the PIPB symbolizes the strong interest and enthusiasm of the plasma physics community for the success of the ITER project, which we all recognize as one of the great scientific challenges of the 21st century. I wish to emphasize my appreciation of the work of the ITPA Coordinating Committee members, who are listed below. Their support and encouragement for the preparation of the PIPB were

  8. Darstellung pathophysiologisch und therapeutisch relevanter Hirnareale psychiatrischer Erkrankungen

    OpenAIRE

    Shababi-Klein, Julia

    2013-01-01

    The aetiology and pathophysiology of psychiatric illnesses like depression or obsessive compulsive disorders are not fully understood, therapy often is insufficient and limited by side effects. Preliminary experimental findings point to a different pathogeny of these illnesses in which genetic, neuroendokrinologische, neuro-biological, neuro-physiological and psychosocial factors play a role. It has been assumed that dysfunctional neuronal circuits , as for example in the area of the cortiko-...

  9. Aspectos relevantes sobre tuberculose para profissionais de saúde

    Directory of Open Access Journals (Sweden)

    Alexandre Daronco

    2012-01-01

    Full Text Available A Tuberculose (TB é uma patologia infectocontagiosa com clínica ampla cujo agentecausador é o Mycobacterium tuberculosis (Bacilo de Koch, uma micobactéria aeróbia estrita. Apesar de tratar-se dedoença antiga, que acomete seres humanos há séculos, sendo uma importante causa de morte no mundo inteiro,diferentes pesquisas do Ministério da Saúde apontam números preocupantes no tocante a novos casos. Materiais eMétodos: O presente artigo de revisão procura, de forma objetiva e clara, explicitar os principais aspectos de interessepara profissionais de saúde no tocante a Tuberculose doença. O artigo divide-se em tópicos: Defi nição, Sintomatologia,Diagnóstico, Tratamento, Multirresistência, Profi laxia, Formas de Contágio e Formas de Prevenção. Foram utilizadasreferências atuais sobre o tema, incluindo Manuais, Guidelines e Artigos científicos diversos de bases de dados comoUp to Date e Science Direct. Discussão: Sinais e sintomas da doença aumentam o grau de suspeição da mesma, oque torna o pedido de exames para confirmação da infecção dentro de tempo hábil para instituição da terapêuticaadequada. Assim como diagnóstico e tratamento, medidas para evitar o contágio, em serviços de saúde, locaiscom aglomerações humanas e em residências, são de fundamental importância no combate a tuberculose. Osprofissionais de saúde devem atentar para possíveis casos de resistência aos fármacos e as indicações de profilaxia,pois tais variáveis são de extrema relevância no controle da disseminação da doença. Conclusão: Por tratar-se dedoença infecciosa que pode acometer todas as classes sociais, além de possuir formas diferentes de acometimento,o conhecimento básico acerca da Tuberculose é deveras imprescindível em serviços de saúde, desde a atençãoprimária até os centros de saúde com alta tecnologia.

  10. Aspectos relevantes do instituto da reeleição

    OpenAIRE

    Zica, Carlos de Oliveira

    2013-01-01

    O Brasil Republicano historicamente adotou o princípio da "não reeleição", o qual foi revogado pela Emenda Constitucional n° 16 de 04 de junho de 1997, aprovada em circunstâncias políticas controvertidas. A essência da reeleição é a de permitir que os políticos que atuem bem continuem sua trajetória, e aqueles que desagradem o eleitorado em seus governos não sejam reeleitos. Contudo, a avaliação de bom e mau governo é uma tarefa para a qual nem todos os eleitores brasileiros estão preparados,...

  11. ASPECTOS RELEVANTES DA EMPRESA INDIVIDUAL DE RESPONSABILIDADE LIMITADA

    Directory of Open Access Journals (Sweden)

    Cezar Verbicaro Moreira PAIS

    2014-02-01

    Full Text Available This paper aims the analysis of the main aspects ofthe law 12.441/2011, which introduced the Individual Limited Liability Company to the Brazilian legislation, through the Civil Code of 2002. Inspired by the foreign law, the EIRELI created a new legal entity that enables the creation of a LLC by an individual entrepreneur. However, the dimness of the law 12.441/2011 brought differing interpretations to the practical application of the institution. Considering the challenges imposed by the new law, by the bills that aim its reform, by the Constitutional Suit that questions the validity of its requirements and by the imminence of a new business law codification, it’s considered necessary to analyze the practical feasibility of this new institution in Corporate Law.

  12. On the theoretical basis for plea bargaining system

    Institute of Scientific and Technical Information of China (English)

    WANG Jiancheng

    2006-01-01

    Before discussing the introduction of the plea bargaining system to China's criminal justice system,it is necessary to study its theoretical basis.Among which,the following aspects should be focused on: the philosophical viewpoint of pragmatism is its thinking basis;the concept of contract is its cultural basis;the structure form of adversary procedure is its systematic basis;and the system of fight to silence and discovery of evidence are its symbiotic basis.

  13. The Role of the Basis Set: Assessing Density Functional Theory

    CERN Document Server

    Boese, A D; Handy, N C; Martin, Jan M. L.; Handy, Nicholas C.

    2003-01-01

    When developing and assessing density functional theory methods, a finite basis set is usually employed. In most cases, however, the issue of basis set dependency is neglected. Here, we assess several basis sets and functionals. In addition, the dependency of the semiempirical fits to a given basis set for a generalised gradient approximation and a hybrid functional is investigated. The resulting functionals are then tested for other basis sets, evaluating their errors and transferability.

  14. Reduced Order Model Basis Vector Generation: Generates Basis Vectors fro ROMs

    Energy Technology Data Exchange (ETDEWEB)

    2016-03-03

    libROM is a library that implements order reduction via singular value decomposition (SVD) of sampled state vectors. It implements 2 parallel, incremental SVD algorithms and one serial, non-incremental algorithm. It also provides a mechanism for adaptive sampling of basis vectors.

  15. Technical basis document for internal dosimetry

    International Nuclear Information System (INIS)

    This document provides the technical basis for the Chem-Nuclear Geotech (Geotech) internal dosimetry program. Geotech policy describes the intentions of the company in complying with radiation protection standards and the as low as reasonably achievable (ALARA) program. It uses this policy and applicable protection standards to derive acceptable methods and levels of bioassay to assure compliance. The models and computational methods used are described in detail within this document. FR-om these models, dose- conversion factors and derived limits are computed. These computations are then verified using existing documentation and verification information or by demonstration of the calculations used to obtain the dose-conversion factors and derived limits. Recommendations for methods of optimizing the internal dosimetry program to provide effective monitoring and dose assessment for workers are provided in the last section of this document. This document is intended to be used in establishing an accredited dosimetry program in accordance with expected Department of Energy Laboratory Accreditation Program (DOELAP) requirements for the selected radionuclides provided in this document, including uranium mill tailing mixtures. Additions and modifications to this document and procedures derived FR-om this document are expected in the future according to changes in standards and changes in programmatic mission

  16. The genetic basis of myeloproliferative disorders.

    Science.gov (United States)

    Skoda, Radek

    2007-01-01

    For many decades, myeloproliferative disorders (MPD) were largely neglected orphan diseases. The conceptual work of William Dameshek in 1951 provided the basis for understanding MPD as a continuum of related syndromes, possibly with a common pathogenetic cause. Recognition of the clonal origin of peripheral blood cells in MPD in 1976 and the ability to grow erythroid colonies in vitro in the absence of added growth factors in 1974 initiated the search for genetic alterations that might be responsible for myeloproliferation. Mutations in the genes for the erythropoietin receptor, thrombopoietin and the von Hippel-Lindau protein were found to cause familial syndromes resembling MPD, but despite their phenotypic similarities, none of these mutations were later found in patients with the sporadic form of MPD. The discovery of activating mutations in the Janus kinase 2 (JAK2) in most patients with MPD has fully transformed and energized the MPD field. Sensitive assays for detecting the JAK2-V617F mutation have become an essential part of the diagnostic work-up, and JAK2 now constitutes a prime target for developing specific inhibitors for the treatment of patients with MPD. Despite this progress, many questions remain unsolved, including how a single JAK2 mutation causes three different MPD phenotypes, what other genes might be involved in the pathogenesis, and what are the factors determining the progression to acute leukemia.

  17. Biological Basis For Computer Vision: Some Perspectives

    Science.gov (United States)

    Gupta, Madan M.

    1990-03-01

    Using biology as a basis for the development of sensors, devices and computer vision systems is a challenge to systems and vision scientists. It is also a field of promising research for engineering applications. Biological sensory systems, such as vision, touch and hearing, sense different physical phenomena from our environment, yet they possess some common mathematical functions. These mathematical functions are cast into the neural layers which are distributed throughout our sensory regions, sensory information transmission channels and in the cortex, the centre of perception. In this paper, we are concerned with the study of the biological vision system and the emulation of some of its mathematical functions, both retinal and visual cortex, for the development of a robust computer vision system. This field of research is not only intriguing, but offers a great challenge to systems scientists in the development of functional algorithms. These functional algorithms can be generalized for further studies in such fields as signal processing, control systems and image processing. Our studies are heavily dependent on the the use of fuzzy - neural layers and generalized receptive fields. Building blocks of such neural layers and receptive fields may lead to the design of better sensors and better computer vision systems. It is hoped that these studies will lead to the development of better artificial vision systems with various applications to vision prosthesis for the blind, robotic vision, medical imaging, medical sensors, industrial automation, remote sensing, space stations and ocean exploration.

  18. Structural basis for spectrin recognition by ankyrin

    Energy Technology Data Exchange (ETDEWEB)

    Ipsaro, Jonathan J.; Mondragón, Alfonso (NWU)

    2010-10-19

    Maintenance of membrane integrity and organization in the metazoan cell is accomplished through intracellular tethering of membrane proteins to an extensive, flexible protein network. Spectrin, the principal component of this network, is anchored to membrane proteins through the adaptor protein ankyrin. To elucidate the atomic basis for this interaction, we determined a crystal structure of human {beta}I-spectrin repeats 13 to 15 in complex with the ZU5-ANK domain of human ankyrin R. The structure reveals the role of repeats 14 to 15 in binding, the electrostatic and hydrophobic contributions along the interface, and the necessity for a particular orientation of the spectrin repeats. Using structural and biochemical data as a guide, we characterized the individual proteins and their interactions by binding and thermal stability analyses. In addition to validating the structural model, these data provide insight into the nature of some mutations associated with cell morphology defects, including those found in human diseases such as hereditary spherocytosis and elliptocytosis. Finally, analysis of the ZU5 domain suggests it is a versatile protein-protein interaction module with distinct interaction surfaces. The structure represents not only the first of a spectrin fragment in complex with its binding partner, but also that of an intermolecular complex involving a ZU5 domain.

  19. Conceptual basis of the master directed diagram

    International Nuclear Information System (INIS)

    This document forms part of a suite of documents describing the Nirex model development programme. The programme is designed to provide a clear audit trail from the identification of significant features, events and processes (FEPs) to the models and modelling processes employed within a detailed safety assessment. A five stage approach has been adopted, which provides a systematic framework for addressing uncertainty and for the documentation of all modelling decisions and assumptions. The five stages are as follows: Stage 1: EP analysis - compilation and structuring of a FEP database; Stage 2: Scenario and conceptual model development; Stage 3: mathematical model development; Stage 4: Software development; Stage 5: confidence building. This report describes the work involved in Stage 1 of the Nirex model development programme, FEP analysis. The aim of FEP analysis is to produce a set of FEPs and FEP interactions that form the basis for the scenario and conceptual model development in Stage 2. There are two requirements for the set of FEPs and FEP interactions; first, all aspects material to the performance of the disposal system should be covered, i.e. the set should be comprehensive, and secondly a clear audit trail of decisions, consensus and analysis should be maintained

  20. Physicochemical and physiological basis of dichromatic colour

    Science.gov (United States)

    Kreft, Samo; Kreft, Marko

    2007-11-01

    Out of three perceptual characteristics of the colour of any substance, the hue depends mostly on the spectral properties of a substance, while the brightness and saturation depend also on the concentration of a substance and its thickness. Here, we report that evident change of the hue of the colour (i.e., from green to red) is due to a change in concentration or the thickness of a layer in some exceptional substances such as pumpkin seed oil or an aqueous solution of bromophenol blue. In some regions of Central Europe, salad dressing is made preferably with the pumpkin seed oil, which has a strong characteristic nut-like taste and remarkable properties of the colour: it appears red in a bottle, but green when served as a salad dressing. The colour of the pumpkin seed oil was previously described as brownish yellow, dark green, dark green to red ochre or dark reddish brown to light yellow green. We elucidated the physicochemical and physiological basis of such dichromatism by Beer-Lambert law and by the characteristics of human colour perception. Our concept was corroborated by the outcome of calculations of colour from spectral properties using colour matching functions. We found that dichromatism is observed if the absorption spectrum of any substance has at least two local minima: one wide but shallow and one narrow but deep local minimum.

  1. Medical basis for radiation accident preparedness

    International Nuclear Information System (INIS)

    The International Conference on The Medical Basis for Radiation Accident Preparedness was organized by the staff of the Radiation Emergency Assistance Center/Training Site (REAC/TS) of the Medical and Health Sciences Division of Oak Ridge Associated Universities (ORAU). The philosophical importance of relating, through investigation and education, the intellectual resources of higher education to the important social problems associated with energy, health, and the environment was the foundation of the meeting. The symposium, held under the auspices of the US Department of Energy, was the ninth since 1960 of a series of international conferences addressing the various aspects of radiation accidents. The approach of this most recent conference differed somewhat from that of those preceding it, in that it sought an international review of the gamut of the medical aspects of radiation injury, not only for the experts in the field, but also for other physicians and scientists who, in view of current events, have had the need to know thrust upon them. Individual entries were made for the separate papers

  2. Electromagnetic Basis of Metabolism and Heredity

    Science.gov (United States)

    Freund, Friedemann; Stolc, Viktor

    2016-01-01

    Living organisms control their cellular biological clocks to maintain functional oscillation of the redox cycle, also called the "metabolic cycle" or "respiratory cycle". Organization of cellular processes requires parallel processing on a synchronized time-base. These clocks coordinate the timing of all biochemical processes in the cell, including energy production, DNA replication, and RNA transcription. When this universal time keeping function is perturbed by exogenous induction of reactive oxygen species (ROS), the rate of metabolism changes. This causes oxidative stress, aging and mutations. Therefore, good temporal coordination of the redox cycle not only actively prevents chemical conflict between the reductive and oxidative partial reactions; it also maintains genome integrity and lifespan. Moreover, this universal biochemical rhythm can be disrupted by ROS induction in vivo. This in turn can be achieved by blocking the electron transport chain either endogenously or exogenously by various metabolites, e.g. hydrogen sulfide (H2S), highly diffusible drugs, and carbon monoxide (CO). Alternatively, the electron transport in vivo can be attenuated via a coherent or interfering transfer of energy from exogenous ultralow frequency (ULF) and extremely low frequency (ELF) electromagnetic (EM) fields, suggesting that-on Earth-such ambient fields are an omnipresent (and probably crucially important) factor for the time-setting basis of universal biochemical reactions in living cells. Our work demonstrated previously un-described evidence for quantum effects in biology by electromagnetic coupling below thermal noise at the universal electron transport chain (ETC) in vivo.

  3. The basis for the strengthening of safeguards

    International Nuclear Information System (INIS)

    For the past 30 years, the International Atomic Energy Agency's safeguards system has contributed to the international non-proliferation regime, by providing, inter alia, assurances regarding the peaceful uses of declared nuclear material. However, the discovery of a clandestine nuclear weapons programme in Iraq in 1991 drew world-wide attention to the need to strengthen the system to address the absence of undeclared nuclear material and activities. Efforts to strengthen the IAEA's safeguards system began in 1991 and culminated in 1997 when the IAEA's Board of Governors approved a Model Protocol Additional to IAEA Safeguards Agreements which greatly expands the legal basis and scope of IAEA safeguards. Within this strengthened system it is expected that the IAEA be able to provide assurance not only of the absence of diversion of declared nuclear material but also on the absence of undeclared nuclear material and activities. This is to be done within a safeguards system that uses an optimal combination of all safeguards measures available, thereby achieving maximum effectiveness and efficiency within the available resources. This paper will summarize the evolution of the safeguards system, describe strengthened safeguards, report on the status of implementing the strengthening measures, and outline plans for integrating all available safeguards measures. (author)

  4. Neuronal basis of amblyopia: A review

    Directory of Open Access Journals (Sweden)

    Grigg John

    1996-01-01

    Full Text Available Amblyopia is an acquired defect in vision due to an abnormal visual experience during a sensitive period of visual development. The neuronal basis of amblyopia is the study of the effects of "abnormal" environmental influences on the genetically programmed development of the visual processing system. Visual pathway development commences with ganglion cells forming the optic nerve. The process that guides these neurones initially to the lateral geniculate nucleus (LGN and then onto the visual cortex is genetically programmed. Initially this process is influenced by spontaneously generated impulses and neurotrophic factors. Following birth, visual stimuli modify and refine the genetically programmed process. Exposure to the visual environment includes the risk of abnormal inputs. Abnormal stimuli disrupt the formation of patterned inputs allowing alteration of visual cortical wiring with reduction in ocular dominance columns driven by the abnormal eye. Correction of the abnormal visual input and penalisation of the "normal" input is the mainstay of therapy for amblyopia. Further understanding of the mechanisms involved in the development of a normal visual processing system will allow trialing therapies for amblyopia not responding to occlusion therapy. Levodopa is one agent providing insights into recovery of visual function for short periods in apparently mature visual systems.

  5. Structural basis for retroviral integration into nucleosomes.

    Science.gov (United States)

    Maskell, Daniel P; Renault, Ludovic; Serrao, Erik; Lesbats, Paul; Matadeen, Rishi; Hare, Stephen; Lindemann, Dirk; Engelman, Alan N; Costa, Alessandro; Cherepanov, Peter

    2015-07-16

    Retroviral integration is catalysed by a tetramer of integrase (IN) assembled on viral DNA ends in a stable complex, known as the intasome. How the intasome interfaces with chromosomal DNA, which exists in the form of nucleosomal arrays, is currently unknown. Here we show that the prototype foamy virus (PFV) intasome is proficient at stable capture of nucleosomes as targets for integration. Single-particle cryo-electron microscopy reveals a multivalent intasome-nucleosome interface involving both gyres of nucleosomal DNA and one H2A-H2B heterodimer. While the histone octamer remains intact, the DNA is lifted from the surface of the H2A-H2B heterodimer to allow integration at strongly preferred superhelix location ±3.5 positions. Amino acid substitutions disrupting these contacts impinge on the ability of the intasome to engage nucleosomes in vitro and redistribute viral integration sites on the genomic scale. Our findings elucidate the molecular basis for nucleosome capture by the viral DNA recombination machinery and the underlying nucleosome plasticity that allows integration.

  6. Theoretical Basis Of The Company Competitiveness Assessment

    Directory of Open Access Journals (Sweden)

    Vladimir Nikiforovich Belkin

    2015-03-01

    Full Text Available The article deals with the basic theoretical questions of the company competitiveness assessment. The state of modern economic thought on this issue is shown. The main factors of the company competitiveness are specified. A specific role of staff of an enterprise is revealed: on the one hand, it is a resource, on the other is a subject, resulting in productive movement all factors of competitiveness, i.e. the staff is a critical factor in the company competitiveness. The criterion of company competitiveness is proposed, on its basis, the concept of “competitive enterprise” is defined. The most well-known approaches for assessing the company competitiveness are analyzed. The author’s method of the company competitiveness assessment based on the dynamics of the integral index of competitiveness is provided. For those cases, when it is impossible to determine the proportion of products on the market, it is proposed to evaluate the company competitiveness on the profitability of its production. The article shows the experience in calculating of the company competitiveness on the proposed author’s methods.

  7. Cellular basis of memory for addiction.

    Science.gov (United States)

    Nestler, Eric J

    2013-12-01

    DESPITE THE IMPORTANCE OF NUMEROUS PSYCHOSOCIAL FACTORS, AT ITS CORE, DRUG ADDICTION INVOLVES A BIOLOGICAL PROCESS: the ability of repeated exposure to a drug of abuse to induce changes in a vulnerable brain that drive the compulsive seeking and taking of drugs, and loss of control over drug use, that define a state of addiction. Here, we review the types of molecular and cellular adaptations that occur in specific brain regions to mediate addiction-associated behavioral abnormalities. These include alterations in gene expression achieved in part via epigenetic mechanisms, plasticity in the neurophysiological functioning of neurons and synapses, and associated plasticity in neuronal and synaptic morphology mediated in part by altered neurotrophic factor signaling. Each of these types of drug-induced modifications can be viewed as a form of "cellular or molecular memory." Moreover, it is striking that most addiction-related forms of plasticity are very similar to the types of plasticity that have been associated with more classic forms of "behavioral memory," perhaps reflecting the finite repertoire of adaptive mechanisms available to neurons when faced with environmental challenges. Finally, addiction-related molecular and cellular adaptations involve most of the same brain regions that mediate more classic forms of memory, consistent with the view that abnormal memories are important drivers of addiction syndromes. The goal of these studies which aim to explicate the molecular and cellular basis of drug addiction is to eventually develop biologically based diagnostic tests, as well as more effective treatments for addiction disorders. PMID:24459410

  8. PARFUME Theory and Model basis Report

    Energy Technology Data Exchange (ETDEWEB)

    Darrell L. Knudson; Gregory K Miller; G.K. Miller; D.A. Petti; J.T. Maki; D.L. Knudson

    2009-09-01

    The success of gas reactors depends upon the safety and quality of the coated particle fuel. The fuel performance modeling code PARFUME simulates the mechanical, thermal and physico-chemical behavior of fuel particles during irradiation. This report documents the theory and material properties behind vari¬ous capabilities of the code, which include: 1) various options for calculating CO production and fission product gas release, 2) an analytical solution for stresses in the coating layers that accounts for irradiation-induced creep and swelling of the pyrocarbon layers, 3) a thermal model that calculates a time-dependent temperature profile through a pebble bed sphere or a prismatic block core, as well as through the layers of each analyzed particle, 4) simulation of multi-dimensional particle behavior associated with cracking in the IPyC layer, partial debonding of the IPyC from the SiC, particle asphericity, and kernel migration (or amoeba effect), 5) two independent methods for determining particle failure probabilities, 6) a model for calculating release-to-birth (R/B) ratios of gaseous fission products that accounts for particle failures and uranium contamination in the fuel matrix, and 7) the evaluation of an accident condition, where a particle experiences a sudden change in temperature following a period of normal irradiation. The accident condi¬tion entails diffusion of fission products through the particle coating layers and through the fuel matrix to the coolant boundary. This document represents the initial version of the PARFUME Theory and Model Basis Report. More detailed descriptions will be provided in future revisions.

  9. Entanglement patterns in mutually unbiased basis sets

    International Nuclear Information System (INIS)

    A few simply stated rules govern the entanglement patterns that can occur in mutually unbiased basis sets (MUBs) and constrain the combinations of such patterns that can coexist in full complements of MUBs. We consider Hilbert spaces of prime power dimensions (D=pN), as realized by systems of N prime-state particles, where full complements of D+1 MUBs are known to exist, and we assume only that MUBs are eigenbases of generalized Pauli operators, without using any particular construction. The general rules include the following: (1) In any MUB, a given particle appears either in a pure state or totally entangled and (2) in any full MUB complement, each particle is pure in (p+1) bases (not necessarily the same ones) and totally entangled in the remaining (pN-p). It follows that the maximum number of product bases is p+1 and, when this number is realized, all remaining (pN-p) bases in the complement are characterized by the total entanglement of every particle. This ''standard distribution'' is inescapable for two-particle systems (of any p), where only product and generalized Bell bases are admissible MUB types. This and the following results generalize previous results for qubits [Phys. Rev. A 65. 032320 (2002); Phys. Rev. A 72, 062310 (2005)] and qutrits [Phys. Rev. A 70, 012302 (2004)], drawing particularly upon [Phys. Rev. A 72, 062310 (2005)]. With three particles there are three MUB types, and these may be combined in (p+2) different ways to form full complements. With N=4, there are 6 MUB types for p=2, but new MUB types become possible with larger p, and these are essential to realizing full complements. With this example, we argue that new MUB types that show new entanglement patterns should enter with every step in N and, also, when N is a prime plus 1, at a critical p value, p=N-1. Such MUBs should play critical roles in filling complements.

  10. JET and the Physics Basis of ITER

    Institute of Scientific and Technical Information of China (English)

    Martin Keilhacker

    2004-01-01

    JET has made unique contributions to the physics basis of ITER by virtue of its ITER-like geometry, large plasma size and D-T capability. The paper discusses recent JET results and their implications for ITER in the areas of standard ELMy H-mode, D-T operation and advanced tokamak modes. In ELMy H-mode the separation of plasma energy into core and pedestal contributions shows that core confinement scales like gyroBohm transport. High triangularity has a beneficial effect on confinement and leads to an integrated plasma performance exceeding the ITER Q =10 reference case. A revised type I ELM scaling predicts acceptable ELM energy losses for ITER, while progress in physics understanding of NTMs shows how to control them in ITER. The D-T experiments of 1997 have validated ICRF scenarios for heating ITER/a reactor and identified ion minority schemes (e.g. (3He)DT) with strong ion heating. They also show that the slowing down of alpha particles is classical so that the self-heating by fusion alphas should cause no unexpected problems. With the Pellet Enhanced Performance mode of 1988, JET has produced the first advanced tokamak mode, with peaked pressure profiles sustained by reversed magnetic shear and strongly reduced transport. More recently, LHCD has provided easy tuning of reversed shear and reliable access to ITBs. Improved physics understanding shows that rational q-surfaces play a key role in the formation and development of ITBs. The demonstration of real time feedback control of plasma current and pressure profiles opens the path towards fully controlled steady-state tokamak plasmas.

  11. The genetic basis of music ability.

    Science.gov (United States)

    Tan, Yi Ting; McPherson, Gary E; Peretz, Isabelle; Berkovic, Samuel F; Wilson, Sarah J

    2014-01-01

    Music is an integral part of the cultural heritage of all known human societies, with the capacity for music perception and production present in most people. Researchers generally agree that both genetic and environmental factors contribute to the broader realization of music ability, with the degree of music aptitude varying, not only from individual to individual, but across various components of music ability within the same individual. While environmental factors influencing music development and expertise have been well investigated in the psychological and music literature, the interrogation of possible genetic influences has not progressed at the same rate. Recent advances in genetic research offer fertile ground for exploring the genetic basis of music ability. This paper begins with a brief overview of behavioral and molecular genetic approaches commonly used in human genetic analyses, and then critically reviews the key findings of genetic investigations of the components of music ability. Some promising and converging findings have emerged, with several loci on chromosome 4 implicated in singing and music perception, and certain loci on chromosome 8q implicated in absolute pitch and music perception. The gene AVPR1A on chromosome 12q has also been implicated in music perception, music memory, and music listening, whereas SLC6A4 on chromosome 17q has been associated with music memory and choir participation. Replication of these results in alternate populations and with larger samples is warranted to confirm the findings. Through increased research efforts, a clearer picture of the genetic mechanisms underpinning music ability will hopefully emerge. PMID:25018744

  12. Authorization basis status report (miscellaneous TWRS facilities, tanks and components)

    International Nuclear Information System (INIS)

    This report presents the results of a systematic evaluation conducted to identify miscellaneous TWRS facilities, tanks and components with potential needed authorization basis upgrades. It provides the Authorization Basis upgrade plan for those miscellaneous TWRS facilities, tanks and components identified

  13. Authorization basis status report (miscellaneous TWRS facilities, tanks and components)

    Energy Technology Data Exchange (ETDEWEB)

    Stickney, R.G.

    1998-04-29

    This report presents the results of a systematic evaluation conducted to identify miscellaneous TWRS facilities, tanks and components with potential needed authorization basis upgrades. It provides the Authorization Basis upgrade plan for those miscellaneous TWRS facilities, tanks and components identified.

  14. The neural basis of bounded rational behavior

    Directory of Open Access Journals (Sweden)

    Coricelli, Giorgio

    2012-03-01

    Full Text Available Bounded rational behaviour is commonly observed in experimental games and in real life situations. Neuroeconomics can help to understand the mental processing underlying bounded rationality and out-of-equilibrium behaviour. Here we report results from recent studies on the neural basis of limited steps of reasoning in a competitive setting —the beauty contest game. We use functional magnetic resonance imaging (fMRI to study the neural correlates of human mental processes in strategic games. We apply a cognitive hierarchy model to classify subject’s choices in the experimental game according to the degree of strategic reasoning so that we can identify the neural substrates of different levels of strategizing. We found a correlation between levels of strategic reasoning and activity in a neural network related to mentalizing, i.e. the ability to think about other’s thoughts and mental states. Moreover, brain data showed how complex cognitive processes subserve the higher level of reasoning about others. We describe how a cognitive hierarchy model fits both behavioural and brain data.

    La racionalidad limitada es un fenómeno observado de manera frecuente tanto en juegos experimentales como en situaciones cotidianas. La Neuroeconomía puede mejorar la comprensión de los procesos mentales que caracterizan la racionalidad limitada; en paralelo nos puede ayudar a comprender comportamientos que violan el equilibrio. Nuestro trabajo presenta resultados recientes sobre la bases neuronales del razonamiento estratégico (y sus límite en juegos competitivos —como el juego del “beauty contest”. Estudiamos las bases neuronales del comportamiento estratégico en juegos con interacción entre sujetos usando resonancia magnética funcional (fMRI. Las decisiones de los participantes se clasifican acorde al grado de razonamiento estratégico: el llamado modelo de Jerarquías Cognitivas. Los resultados muestran una correlación entre niveles de

  15. The neural circuit basis of learning

    Science.gov (United States)

    Patrick, Kaifosh William John

    The astounding capacity for learning ranks among the nervous system's most impressive features. This thesis comprises studies employing varied approaches to improve understanding, at the level of neural circuits, of the brain's capacity for learning. The first part of the thesis contains investigations of hippocampal circuitry -- both theoretical work and experimental work in the mouse Mus musculus -- as a model system for declarative memory. To begin, Chapter 2 presents a theory of hippocampal memory storage and retrieval that reflects nonlinear dendritic processing within hippocampal pyramidal neurons. As a prelude to the experimental work that comprises the remainder of this part, Chapter 3 describes an open source software platform that we have developed for analysis of data acquired with in vivo Ca2+ imaging, the main experimental technique used throughout the remainder of this part of the thesis. As a first application of this technique, Chapter 4 characterizes the content of signaling at synapses between GABAergic neurons of the medial septum and interneurons in stratum oriens of hippocampal area CA1. Chapter 5 then combines these techniques with optogenetic, pharmacogenetic, and pharmacological manipulations to uncover inhibitory circuit mechanisms underlying fear learning. The second part of this thesis focuses on the cerebellum-like electrosensory lobe in the weakly electric mormyrid fish Gnathonemus petersii, as a model system for non-declarative memory. In Chapter 6, we study how short-duration EOD motor commands are recoded into a complex temporal basis in the granule cell layer, which can be used to cancel Purkinje-like cell firing to the longer duration and temporally varying EOD-driven sensory responses. In Chapter 7, we consider not only the temporal aspects of the granule cell code, but also the encoding of body position provided from proprioceptive and efference copy sources. Together these studies clarify how the cerebellum-like circuitry of the

  16. 9 CFR 590.130 - Basis of billing plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Basis of billing plants. 590.130... of Service § 590.130 Basis of billing plants. Overtime and/or holiday services shall be billed to the official plant on the basis of each 15 minutes of overtime and/or holiday service performed by...

  17. Basis Invariants in Non--Abelian Gauge Theories

    OpenAIRE

    Müller, Uwe

    1997-01-01

    A basis of Lorentz and gauge-invariant monomials in non--Abelian gauge theories with matter is described, applicable for the inverse mass expansion of effective actions. An algorithm to convert an arbitrarily given invariant expression into a linear combination of the basis elements is presented. The linear independence of the basis invariants is proven.

  18. 26 CFR 1.167(g)-1 - Basis for depreciation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Basis for depreciation. 1.167(g)-1 Section 1.167... for depreciation. The basis upon which the allowance for depreciation is to be computed with respect... property at that time, is the basis for computing depreciation....

  19. Property-optimized Gaussian basis sets for molecular response calculations

    Science.gov (United States)

    Rappoport, Dmitrij; Furche, Filipp

    2010-10-01

    With recent advances in electronic structure methods, first-principles calculations of electronic response properties, such as linear and nonlinear polarizabilities, have become possible for molecules with more than 100 atoms. Basis set incompleteness is typically the main source of error in such calculations since traditional diffuse augmented basis sets are too costly to use or suffer from near linear dependence. To address this problem, we construct the first comprehensive set of property-optimized augmented basis sets for elements H-Rn except lanthanides. The new basis sets build on the Karlsruhe segmented contracted basis sets of split-valence to quadruple-zeta valence quality and add a small number of moderately diffuse basis functions. The exponents are determined variationally by maximization of atomic Hartree-Fock polarizabilities using analytical derivative methods. The performance of the resulting basis sets is assessed using a set of 313 molecular static Hartree-Fock polarizabilities. The mean absolute basis set errors are 3.6%, 1.1%, and 0.3% for property-optimized basis sets of split-valence, triple-zeta, and quadruple-zeta valence quality, respectively. Density functional and second-order Møller-Plesset polarizabilities show similar basis set convergence. We demonstrate the efficiency of our basis sets by computing static polarizabilities of icosahedral fullerenes up to C720 using hybrid density functional theory.

  20. Espacio literario relevante sobre el problema del vendedor viajero (TSP: contenido, clasificación, métodos y campos de inspiración Relevant literary space on travelling salesman problem (TSP: contents, classification, methods and fields of inspiration

    Directory of Open Access Journals (Sweden)

    Jorge Ivan Pérez Rave

    2013-01-01

    Full Text Available Se describe y se analiza un espacio literario relevante sobre el Problema del Vendedor Viajero (TSP en términos de contenido, clases de TSP, métodos y campos de inspiración. Los datos empleados provinieron de los trabajos más citados en Scopus sobre el TSP, tanto a través de la historia como en el período 2006-2010. Se encontró que el TSP prevalece en las investigaciones, con enfoques tanto en el problema original como en sus variantes, entre las cuales se identificaron el TSP Múltiple y el TSP Probabilístico. Entre los principales campos de inspiración para resolver el TSP están la evolución biológica y su base genético-molecular, el comportamiento de hormigas reales, la termodinámica, las estrategias sistemáticas para combinar reglas de decisión y la búsqueda de vecindades. Hoy día se tiende a desarrollar métodos híbridos, especialmente integrando enfoques globales con búsquedas locales, y se identifica la necesidad de introducir nuevos campos de inspiración.This paper describes and analyzes, in terms of content, the types of TSP, methods and fields of inspiration - the most relevant "literary space" on TSP. It is built based on the top most cited on the TSP history and the Top 10 cited from 2006 to 2010. The study of TSP still prevails in Research, focusing on the original problem and its variants: Multiple TSP (m-TSP and Probabilistic TSP (PTSP. Evidence shows that there has been progress in the development of TSP solving methods, highlighted by various inspiration fields: biological evolution, behavior of real ants, thermodynamics, systematic strategies for combining decision rules, and neighborhood search. There is a tendency to develop hybrid methods, in particular by integrating global approaches to local search. There is need to introduce new fields of inspiration.

  1. Ocorrência de bactérias clinicamente relevantes nos resíduos de serviços de saúde em um aterro sanitário brasileiro e perfil de susceptibilidade a antimicrobianos Occurrence of clinically relevant bacteria in health service waste in a Brazilian sanitary landfill and antimicrobial susceptibility profile

    Directory of Open Access Journals (Sweden)

    Thiago César Nascimento

    2009-08-01

    Full Text Available Os resíduos de serviços de saúde suscitam polêmica quanto a importância para a saúde humana, animal e ambiental. Avaliou-se a ocorrência de bactérias clinicamente relevantes na pilha de resíduos de serviços de saúde em um aterro sanitário e seu perfil de susceptibilidade aos antimicrobianos. Alíquotas de chorume foram processadas para isolamento seletivo de Staphylococcus sp, bastonetes Gram negativos da família Enterobacteriaceae e não fermentadores. Resistência bacteriana a todos os antimicrobianos testados foi observada em todos os grupos microbianos, além de resistência a mais de uma droga. Os resultados permitem sugerir que bactérias viáveis nos resíduos de serviços de saúde representam riscos à saúde humana e animal. Além disso, a ocorrência de linhagens multirresistentes sustenta a hipótese dos resíduos de serviços de saúde atuarem como reservatórios de marcadores de resistência, com impacto ambiental. A falta de legislação regional de segregação, tratamento e destino de resíduos podem expor diferentes populações a riscos de transmissão de doenças infecciosas associadas a microrganismos multirresistentes.Health service waste gives rise to controversy regarding its importance for human, animal and environmental health. Occurrences of clinically relevant bacteria in piles of health service waste in a sanitary landfill and their antimicrobial susceptibility profile were evaluated. Aliquots of leachate were processed for selective isolation of Staphylococcus sp, Gram-negative rods of the Enterobacteriaceae family and non-fermenters. Bacterial resistance to all the antimicrobials tested was observed in all microbial groups, including resistance to more than one drug. The results make it possible to suggest that viable bacteria in health service waste represent risks to human and animal health. Furthermore, occurrences of multiresistant strains support the hypothesis that health service waste acts as a

  2. Design basis reconstitution for an effective design control program

    International Nuclear Information System (INIS)

    Configuration management is a new buzz word in the nuclear power industry. Whatever its definition, everyone agrees that the configuration of a nuclear power plant must be managed effectively. In layman's terms, configuration management means that a plant must be built, operated, and maintained in a manner consistent with its design basis. Thus, control of the design basis is the most important element in any configuration management program. Until recently, the US Nuclear Regulatory Commission's (NRC's) review of design basis focused on the plants that were about to get operating licenses. However, incidents at a few operating nuclear plants and NRC inspections (Safety System Functional Inspection and Safety System Outage Modification Inspection) have indicated weaknesses in older operating plant design basis documentation and design change control programs. Thus, reconstitution of plant design basis has become an important issue. This paper presents the major element of a design basis reconstitution program, which can be an immense undertaking for some of the older operating plants

  3. Differential Forms Basis Functions for Better Conditioned Integral Equations

    Energy Technology Data Exchange (ETDEWEB)

    Fasenfest, B; White, D; Stowell, M; Rieben, R; Sharpe, R; Madsen, N; Rockway, J D; Champagne, N J; Jandhyala, V; Pingenot, J

    2005-01-13

    Differential forms offer a convenient way to classify physical quantities and set up computational problems. By observing the dimensionality and type of derivatives (divergence,curl,gradient) applied to a quantity, an appropriate differential form can be chosen for that quantity. To use these differential forms in a simulation, the forms must be discretized using basis functions. The 0-form through 2-form basis functions are formed for surfaces. Twisted 1-form and 2-form bases will be presented in this paper. Twisted 1-form (1-forms) basis functions ({Lambda}) are divergence-conforming edge basis functions with units m{sup -1}. They are appropriate for representing vector quantities with continuous normal components, and they belong to the same function space as the commonly used RWG bases [1]. They are used here to formulate the frequency-domain EFIE with Galerkin testing. The 2-form basis functions (f) are scalar basis functions with units m{sup -2} and with no enforced continuity between elements. At lowest order, the 2-form basis functions are similar to pulse basis functions. They are used here to formulate an electrostatic integral equation. It should be noted that the derivative of an n-form differential form basis function is an (n+1)-form, i.e. the derivative of a 1-form basis function is a 2-form. Because the basis functions are constructed such that they have spatial units, the spatial units are removed from the degrees of freedom, leading to a better-conditioned system matrix. In this conference paper, we look at the performance of these differential forms and bases by examining the conditioning of matrix systems for electrostatics and the EFIE. The meshes used were refined across the object to consider the behavior of these basis transforms for elements of different sizes.

  4. Knowledge basis in safety culture for researchers and practitioners

    International Nuclear Information System (INIS)

    This paper presents the main characteristics of the knowledge basis in safety culture which is being developed at the IPEN-CNEN/SP, one of the Brazilian nuclear institutes of research. The main objective of this basis is to organize the information about safety culture found in the literature and to make it available to researchers and practitioners. The first stage of the development of this basis is already finished being the subject of this work. (author)

  5. Birman—Wenzl—Murakami Algebra and Topological Basis

    Science.gov (United States)

    Zhou, Cheng-Cheng; Xue, Kang; Wang, Gang-Cheng; Sun, Chun-Fang; Du, Gui-Jiao

    2012-02-01

    In this paper, we use entangled states to construct 9 × 9-matrix representations of Temperley—Lieb algebra (TLA), then a family of 9 × 9-matrix representations of Birman—Wenzl—Murakami algebra (BWMA) have been presented. Based on which, three topological basis states have been found. And we apply topological basis states to recast nine-dimensional BWMA into its three-dimensional counterpart. Finally, we find the topological basis states are spin singlet states in special case.

  6. Side effects of normalising radial basis function networks.

    Science.gov (United States)

    Shorten, R; Murray-Smith, R

    1996-05-01

    Normalisation of the basis function activations in a Radial Basis Function (RBF) network is a common way of achieving the partition of unity often desired for modelling applications. It results in the basis functions covering the whole of the input space to the same degree. However, normalisation of the basis functions can lead to other effects which are sometimes less desirable for modelling applications. This paper describes some side effects of normalisation which fundamentally alter properties of the basis functions, e.g. the shape is no longer uniform, maxima of basis functions can be shifted from their centres, and the basis functions are no longer guaranteed to decrease monotonically as distance from their centre increases--in many cases basis functions can 'reactivate', i.e. re-appear far from the basis function centre. This paper examines how these phenomena occur, discusses their relevance for non-linear function approximation and examines the effect of normalisation on the network condition number and weights.

  7. Correct quantum chemistry in a minimal basis from effective Hamiltonians

    CERN Document Server

    Watson, Thomas J

    2015-01-01

    We describe how to create ab-initio effective Hamiltonians that qualitatively describe correct chemistry even when used with a minimal basis. The Hamiltonians are obtained by folding correlation down from a large parent basis into a small, or minimal, target basis, using the machinery of canonical transformations. We demonstrate the quality of these effective Hamiltonians to correctly capture a wide range of excited states in water, nitrogen, and ethylene, and to describe ground and excited state bond-breaking in nitrogen and the chromium dimer, all in small or minimal basis sets.

  8. Extension of the basis set of linearized augmented plane wave (LAPW) method by using supplemented tight binding basis functions

    Science.gov (United States)

    Nikolaev, A. V.; Lamoen, D.; Partoens, B.

    2016-07-01

    In order to increase the accuracy of the linearized augmented plane wave (LAPW) method, we present a new approach where the plane wave basis function is augmented by two different atomic radial components constructed at two different linearization energies corresponding to two different electron bands (or energy windows). We demonstrate that this case can be reduced to the standard treatment within the LAPW paradigm where the usual basis set is enriched by the basis functions of the tight binding type, which go to zero with zero derivative at the sphere boundary. We show that the task is closely related with the problem of extended core states which is currently solved by applying the LAPW method with local orbitals (LAPW+LO). In comparison with LAPW+LO, the number of supplemented basis functions in our approach is doubled, which opens up a new channel for the extension of the LAPW and LAPW+LO basis sets. The appearance of new supplemented basis functions absent in the LAPW+LO treatment is closely related with the existence of the u ˙ l -component in the canonical LAPW method. We discuss properties of additional tight binding basis functions and apply the extended basis set for computation of electron energy bands of lanthanum (face and body centered structures) and hexagonal close packed lattice of cadmium. We demonstrate that the new treatment gives lower total energies in comparison with both canonical LAPW and LAPW+LO, with the energy difference more pronounced for intermediate and poor LAPW basis sets.

  9. 42 CFR 422.1 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... PROGRAM MEDICARE ADVANTAGE PROGRAM General Provisions § 422.1 Basis and scope. (a) Basis. This part is... enrollment. 1852—Benefits and beneficiary protections. 1853—Payments to Medicare Advantage (MA) organizations..., limitations, and procedures for Medicare services furnished, or paid for, by Medicare Advantage...

  10. 42 CFR 410.1 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... SUPPLEMENTARY MEDICAL INSURANCE (SMI) BENEFITS General Provisions § 410.1 Basis and scope. (a) Statutory basis...—Scope of benefits furnished under the Medicare Part B supplementary medical insurance (SMI) program. (2) Section 1833 through 1835 and 1862—Amounts of payment for SMI services, the conditions for payment,...

  11. 42 CFR 407.1 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... SUPPLEMENTARY MEDICAL INSURANCE (SMI) ENROLLMENT AND ENTITLEMENT General Provisions § 407.1 Basis and scope. (a) Statutory basis. The supplementary medical insurance (SMI) program is authorized by Part B of title XVIII of... pay the SMI premiums for, eligible individuals who are also eligible for cash assistance or...

  12. 7 CFR 58.132 - Basis for classification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Basis for classification. 58.132 Section 58.132 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Milk § 58.132 Basis for classification. The quality classification of raw milk for...

  13. Personal Data Processing for Behavioural Targeting: Which Legal Basis?

    NARCIS (Netherlands)

    F.J. Zuiderveen Borgesius

    2015-01-01

    Key Points •The European Union Charter of Fundamental Rights only allows personal data processing if a data controller has a legal basis for the processing. •This paper argues that, in most circumstances, the only available legal basis for the processing of personal data for behavioural targeting is

  14. Higher-Order Hierarchical Legendre Basis Functions in Applications

    DEFF Research Database (Denmark)

    Kim, Oleksiy S.; Jørgensen, Erik; Meincke, Peter;

    2007-01-01

    degree of orthogonality. The basis functions are well-suited for solution of complex electromagnetic problems involving multiple homogeneous or inhomogeneous dielectric regions, metallic surfaces, layered media, etc. This paper presents real-life complex antenna radiation problems modeled...... with electromagnetic simulation tools based on the higher-order hierarchical Legendre basis functions....

  15. Fuzzy State Comprehensive Evaluation of Living Basis for Small Businesses

    Institute of Scientific and Technical Information of China (English)

    CHEN Ya-rong; TANG Bing-yong; LI Ling X.

    2002-01-01

    The problem of comprehensive evaluation of liying basis for small businesses is discussed, based on fuzziness of index, a corresponding fuzzy state comprehensive evaluation method is presented; the good results that is,the evaluation of living basis for small business are illustrated by a simulated example.

  16. EEG Source Reconstruction using Sparse Basis Function Representations

    DEFF Research Database (Denmark)

    Hansen, Sofie Therese; Hansen, Lars Kai

    2014-01-01

    State of the art performance of 3D EEG imaging is based on reconstruction using spatial basis function representations. In this work we augment the Variational Garrote (VG) approach for sparse approximation to incorporate spatial basis functions. As VG handles the bias variance trade-off with cross...

  17. TECHNICAL BASIS FOR A CANDIDATE BUILDING MATERIALS RADIUM STANDARD

    Science.gov (United States)

    The report summarizes the technical basis for a candidate building materials radium standard. It contains the standard and a summary of the technical basis for the standard. (NOTE: The Florida Radon Research Program (FRRP), sponsored by the Environmental Protection Agency and the...

  18. 47 CFR 95.1400 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Basis and purpose. 95.1400 Section 95.1400 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Personal Locator Beacons (PLB). § 95.1400 Basis and purpose. The rules in this subpart...

  19. Localized atomic basis set in the projector augmented wave method

    DEFF Research Database (Denmark)

    Larsen, Ask Hjorth; Vanin, Marco; Mortensen, Jens Jørgen;

    2009-01-01

    We present an implementation of localized atomic-orbital basis sets in the projector augmented wave (PAW) formalism within the density-functional theory. The implementation in the real-space GPAW code provides a complementary basis set to the accurate but computationally more demanding grid...

  20. 40 CFR 35.162 - Basis for allotment.

    Science.gov (United States)

    2010-07-01

    ... made on the basis of the cumulative change in the Consumer Price Index (CPI), published by the U.S... fiscal year. These adjustments will be made on the basis of the cumulative change in the Consumer Price... Pollution Control State grant allotment formula are: Surface Water Area; Ground Water Use; Water...

  1. Higher Order Hierarchical Legendre Basis Functions for Electromagnetic Modeling

    DEFF Research Database (Denmark)

    Jørgensen, Erik; Volakis, John L.; Meincke, Peter;

    2004-01-01

    This paper presents a new hierarchical basis of arbitrary order for integral equations solved with the Method of Moments (MoM). The basis is derived from orthogonal Legendre polynomials which are modified to impose continuity of vector quantities between neighboring elements while maintaining most....... In addition, all higher-order terms in the expansion have two vanishing moments.In contrast to existing formulations, these properties allow the use of very high-order basis functions without introducing ill-conditioning of the resulting MoM matrix. Numerical results confirm that the condition number...... of the MoM matrix obtained with this new basis is much lower than existing higher-order interpolatory and hierarchical basis functions. As a consequence of the excellent condition numbers, we demonstrate that even very high-order MoM systems, e.g. 10th order, can be solved efficiently with an iterative...

  2. Radial basis function network design for chaotic time series prediction

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Chang Yong; Kim, Taek Soo; Park, Sang Hui [Yonsei University, Seoul (Korea, Republic of); Choi, Yoon Ho [Kyonggi University, Suwon (Korea, Republic of)

    1996-04-01

    In this paper, radial basis function networks with two hidden layers, which employ the K-means clustering method and the hierarchical training, are proposed for improving the short-term predictability of chaotic time series. Furthermore the recursive training method of radial basis function network using the recursive modified Gram-Schmidt algorithm is proposed for the purpose. In addition, the radial basis function networks trained by the proposed training methods are compared with the X.D. He A Lapedes`s model and the radial basis function network by non-recursive training method. Through this comparison, an improved radial basis function network for predicting chaotic time series is presented. (author). 17 refs., 8 figs., 3 tabs.

  3. BASIS FOR DETERMINATION OF CHEMICAL STABILITY and COMPATIBILITY OF SOLID WASTE CHEMICAL COMPATIBILITY TECHNICAL BASIS

    International Nuclear Information System (INIS)

    Solid wastes must be managed to prevent inadvertent reactions, explosion and degradation of waste containers per the ''Washington State Department of Ecology Dangerous Waste Regulations'' (WAC 173-303). An understanding of chemical compatibility principles and a consistent approach for implementing compatibility requirements is essential for complying with the regulations. This document explains the technical basis for ensuring chemical compatibility for solid wastes that are stored on site at on-site TSD facilities and for solid waste that will go to off-site TSD facilities. The document applies directly to the following aspects of chemical compatibility: (1) Ensuring that hazardous waste is not chemically reactive or unstable such that it cannot be safely transported or stored; (2) Ensuring that lab packs (i.e., drums containing multiple inner containers of differing types of hazardous waste) are packaged such that incompatible chemicals are not placed into the same drum; (3) Selecting containers and liners that are compatible with the waste they contain. This document does not cover individual TSD requirements, or specific offsite TSD requirements. This document does not cover chemical compatibility and segregation requirements for shipping wastes on-site or off-site. This document does not cover radiological hazards associated with radioactive waste or mixed wastes. Evaluation of compatibility for comingling and treating solid waste is beyond the scope of this document. In addition, heat generation and gas generation as they apply to the Hanford waste acceptance criteria are not covered in this document

  4. The Dual Functionals for the Generalized Ball Basis of Wang-Said Type and Basis Transformation Formulas

    Institute of Scientific and Technical Information of China (English)

    Ping Jiang; Hongyi Wu; Jieqing Tan

    2006-01-01

    The generalized Ball curves of Wang-Said type with a position parameter L not only unify the Wang-Ball curves and the Said-Ball curves, but also include several useful intermediate curves. This paper presents the dual functionals for the generalized Ball basis of Wang-Said type. The relevant basis transformation formulae are also worked out.

  5. Las tecnologías médicas más relevantes de los últimos 25 años según la opinión de médicos generalistas The opinion of practitioners and internists on the impact of health technologies introduced in the last 25 years

    Directory of Open Access Journals (Sweden)

    Mireia Espallargues

    2008-02-01

    Full Text Available Objetivos: Identificar las innovaciones médicas más relevantes de los últimos 25 años y conocer su impacto sobre la salud de los pacientes según la opinión de los médicos generalistas. Métodos: Estudio descriptivo transversal. Se seleccionaron las 30 tecnologías que habían recibido más citas bibliométricas en los últimos 25 años (1977-2002 en revistas médicas generalistas y de atención primaria. Para la evaluación de su impacto se encuestó por correo a los responsables médicos de 46 hospitales (entre 100 y 400 camas y a una muestra aleatoria igual de directores de centros de atención primaria de Cataluña. Se pidió que valoraran las tecnologías cuya ausencia comportaría los mayores o menores efectos negativos sobre la salud de los pacientes. Se recogieron características profesionales y de los centros de los participantes. Resultados: Se obtuvo respuesta de 49 médicos (53%. Las tecnologías diagnósticas y las instrumentales han tenido un mayor impacto sobre la salud, y la ecografía fue la mejor valorada. En el otro extremo, se consideran diversos tratamientos farmacológicos, y los hipoglucemiantes orales fueron los menos valorados. Las valoraciones no fueron muy distintas según las características de los encuestados (r ≥ 0,7, aunque aparecieron algunas diferencias en las tecnologías diagnósticas y se observó cierta variabilidad en las respuestas. Conclusiones: La valoración del impacto de 30 tecnologías por médicos generalistas es variable, pero parece que las tecnologías diagnósticas e instrumentales a través de la imagen se valoran mejor que las farmacológicas. Esta variabilidad parece más relacionada con características individuales de los profesionales que con diferencias en sus ámbitos de práctica.Objectives: To identify the most important health technologies (HT introduced in the last 25 years and their impact on patients' health according to hospital internists and generalist physicians

  6. Integration of macromolecular diffraction data using radial basis function networks.

    Science.gov (United States)

    Pokrić, B; Allinson, N M; Helliwell, J R

    2000-11-01

    This paper presents a novel approach for intensity calculation of X-ray diffraction spots based on a two-stage radial basis function (RBF) network. The first stage uses pre-determined reference profiles from a database as basis functions in order to locate the diffraction spots and identify any overlapping regions. The second-stage RBF network employs narrow basis functions capable of local modifications of the reference profiles leading to a more accurate observed diffraction spot approximation and therefore accurate determination of spot positions and integrated intensities.

  7. Wavelet basis construction method based on separation blast vibration signal

    Institute of Scientific and Technical Information of China (English)

    凌同华; 张胜; 陈倩倩; 李洁

    2015-01-01

    As wavelet basis in wavelet analysis is neither arbitrary nor unique, the same signal dealing with different wavelet bases will generate different results. Therefore, how to construct a wavelet basis suitable for the characteristics of the analyzed signal and solve its algorithm and realization is a fundamental problem which perplexed many researchers. To solve these problems, in accordance with the basic features of the measured millisecond blast vibration signal, a new wavelet basis construction method based on the separation blast vibration signal is proposed, and the feasibility of this method is verified by comparing the practical effect of the newly constructed wavelet with other known wavelets in signal processing.

  8. 45 CFR 170.400 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION... FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.400 Basis and scope... and procedures related to the temporary certification program for health information...

  9. Molecular Basis of Microbial One-Carbon Metabolism

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-07-12

    The Gordon Research Conference (GRC) on Molecular Basis of Microbial One-Carbon Metabolism was held at Connecticut College, New London, Connecticut. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

  10. 42 CFR 441.100 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... Individuals Age 65 or Over in Institutions for Mental Diseases § 441.100 Basis and purpose. This subpart... in an institution for mental diseases, and sections 1902(a)(20)(B) and (C) and 1902(a)(21),...

  11. Radial basis function neural networks applied to NASA SSME data

    Science.gov (United States)

    Wheeler, Kevin R.; Dhawan, Atam P.

    1993-01-01

    This paper presents a brief report on the application of Radial Basis Function Neural Networks (RBFNN) to the prediction of sensor values for fault detection and diagnosis of the Space Shuttle's Main Engines (SSME). The location of the Radial Basis Function (RBF) node centers was determined with a K-means clustering algorithm. A neighborhood operation about these center points was used to determine the variances of the individual processing notes.

  12. The finite element method its basis and fundamentals

    CERN Document Server

    Zienkiewicz, Olek C; Zhu, JZ

    2013-01-01

    The Finite Element Method: Its Basis and Fundamentals offers a complete introduction to the basis of the finite element method, covering fundamental theory and worked examples in the detail required for readers to apply the knowledge to their own engineering problems and understand more advanced applications. This edition sees a significant rearrangement of the book's content to enable clearer development of the finite element method, with major new chapters and sections added to cover: Weak forms Variational forms Multi-dimensional field prob

  13. Dynamic Analysis of Wind Turbine Blades Using Radial Basis Functions

    OpenAIRE

    Ming-Hung Hsu

    2011-01-01

    Wind turbine blades play important roles in wind energy generation. The dynamic problems associated with wind turbine blades are formulated using radial basis functions. The radial basis function procedure is used to transform partial differential equations, which represent the dynamic behavior of wind turbine blades, into a discrete eigenvalue problem. Numerical results demonstrate that rotational speed significantly impacts the first frequency of a wind turbine blade. Moreover, the...

  14. Technical Basis Document for PFP Area Monitoring Dosimetry Program

    CERN Document Server

    Cooper, J R

    2000-01-01

    This document describes the phantom dosimetry used for the PFP Area Monitoring program and establishes the basis for the Plutonium Finishing Plant's (PFP) area monitoring dosimetry program in accordance with the following requirements: Title 10, Code of Federal Regulations (CFR), part 835, ''Occupational Radiation Protection'' Part 835.403; Hanford Site Radiological Control Manual (HSRCM-1), Part 514; HNF-PRO-382, Area Dosimetry Program; and PNL-MA-842, Hanford External Dosimetry Technical Basis Manual.

  15. Orthogonal least squares learning algorithm for radial basis function networks

    Energy Technology Data Exchange (ETDEWEB)

    Chen, S.; Cowan, C.F.N.; Grant, P.M. (Dept. of Electrical Engineering, Univ. of Edinburgh, Mayfield Road, Edinburgh EH9 3JL, Scotland (GB))

    1991-03-01

    The radial basis function network offers a viable alternative to the two-layer neural network in many applications of signal processing. A common learning algorithm for radial basis function networks is based on first choosing randomly some data points as radial basis function centers and then using singular value decomposition to solve for the weights of the network. Such a procedure has several drawbacks and, in particular, an arbitrary selection of centers is clearly unsatisfactory. The paper proposes an alternative learning procedure based on the orthogonal least squares method. The procedure choose radial basis function centers one by one in a rational way until an adequate network has been constructed. The algorithm has the property that each selected center maximizes the increment to the explained variance or energy of the desired output and does not suffer numerical ill-conditioning problems. The orthogonal least squares learning strategy provides a simple and efficient means for fitting radial basis function networks, and this is illustrated using examples taken from two different signal processing applications.

  16. Orthogonal least squares learning algorithm for radial basis function networks.

    Science.gov (United States)

    Chen, S; Cowan, C N; Grant, P M

    1991-01-01

    The radial basis function network offers a viable alternative to the two-layer neural network in many applications of signal processing. A common learning algorithm for radial basis function networks is based on first choosing randomly some data points as radial basis function centers and then using singular-value decomposition to solve for the weights of the network. Such a procedure has several drawbacks, and, in particular, an arbitrary selection of centers is clearly unsatisfactory. The authors propose an alternative learning procedure based on the orthogonal least-squares method. The procedure chooses radial basis function centers one by one in a rational way until an adequate network has been constructed. In the algorithm, each selected center maximizes the increment to the explained variance or energy of the desired output and does not suffer numerical ill-conditioning problems. The orthogonal least-squares learning strategy provides a simple and efficient means for fitting radial basis function networks. This is illustrated using examples taken from two different signal processing applications.

  17. Efficient computation of smoothing splines via adaptive basis sampling

    KAUST Repository

    Ma, Ping

    2015-06-24

    © 2015 Biometrika Trust. Smoothing splines provide flexible nonparametric regression estimators. However, the high computational cost of smoothing splines for large datasets has hindered their wide application. In this article, we develop a new method, named adaptive basis sampling, for efficient computation of smoothing splines in super-large samples. Except for the univariate case where the Reinsch algorithm is applicable, a smoothing spline for a regression problem with sample size n can be expressed as a linear combination of n basis functions and its computational complexity is generally O(n3). We achieve a more scalable computation in the multivariate case by evaluating the smoothing spline using a smaller set of basis functions, obtained by an adaptive sampling scheme that uses values of the response variable. Our asymptotic analysis shows that smoothing splines computed via adaptive basis sampling converge to the true function at the same rate as full basis smoothing splines. Using simulation studies and a large-scale deep earth core-mantle boundary imaging study, we show that the proposed method outperforms a sampling method that does not use the values of response variables.

  18. Análise qualitativa de variáveis relevantes para a aplicação do programa de terapia psicológica integrada em pacientes com esquizofrenia de três centros do Sul do Brasil Qualitative analysis of relevant variables for the application of the integrated psychological therapy program in patients with schizophrenia in three Southern Brazilian centers

    Directory of Open Access Journals (Sweden)

    Marilene Zimmer

    2006-12-01

    Full Text Available OBJETIVOS: São dois os propósitos deste estudo: apresentar as principais dificuldades que temos encontrado com a aplicação do programa de terapia psicológica integrada para esquizofrenia Integrated Psychological Therapy (IPT, desenvolvido na Alemanha, e fundamentar as estratégias que temos utilizado para adaptar essa técnica à nossa realidade brasileira. MÉTODO: Abordagem qualitativa, com análise de dados, através do conteúdo das verbalizações dos pacientes, em grupos de discussão realizados após sessões terapêuticas da técnica, com três grupos de pacientes diagnosticados de esquizofrenia ou transtorno esquizoafetivo, de acordo com o Manual de Diagnóstico e Estatística das Perturbações Mentais, provenientes de três instituições diferentes, que trabalham com a aplicação do IPT - Instituto de Capacitação e Reorientação Ocupacional, Centro de Atenção Psicossocial do Hospital de Clínicas de Porto Alegre e Centro de Atenção Psicossocial de Tubarão (SC -, totalizando 22 pacientes. RESULTADOS: Foram levantadas as seguintes categorias: repetição e monotonia; dificuldades de execução de alguns exercícios; falta de utilidade prática de alguns exercícios; e necessidade de saber mais sobre a doença. Também foram encontrados aspectos positivos da técnica relatados pelos pacientes. DISCUSSÃO: Os resultados evidenciam aspectos muito relevantes para entender a motivação dos pacientes para a adesão ao tratamento com essa abordagem desenvolvida em um país europeu. Nossos achados sugerem que as diferenças culturais podem interferir na aplicação do IPT quanto à sua estruturação; entretanto, a melhora de funcionamento, como relatado pelos próprios pacientes, motiva-nos a continuar buscando a adaptação dessa técnica para as características de nossos pacientes. Contudo, são necessários outros estudos no futuro, como ensaio clínico controlado, para avaliar mais especificamente a efetividade da adapta

  19. Point Set Denoising Using Bootstrap-Based Radial Basis Function

    Science.gov (United States)

    Ramli, Ahmad; Abd. Majid, Ahmad

    2016-01-01

    This paper examines the application of a bootstrap test error estimation of radial basis functions, specifically thin-plate spline fitting, in surface smoothing. The presence of noisy data is a common issue of the point set model that is generated from 3D scanning devices, and hence, point set denoising is one of the main concerns in point set modelling. Bootstrap test error estimation, which is applied when searching for the smoothing parameters of radial basis functions, is revisited. The main contribution of this paper is a smoothing algorithm that relies on a bootstrap-based radial basis function. The proposed method incorporates a k-nearest neighbour search and then projects the point set to the approximated thin-plate spline surface. Therefore, the denoising process is achieved, and the features are well preserved. A comparison of the proposed method with other smoothing methods is also carried out in this study. PMID:27315105

  20. Minimal Basis in Four Dimensions and Scalar Blocks

    CERN Document Server

    Cachazo, Freddy

    2016-01-01

    We find a construction that expresses any tree-level $n$-particle ${\\rm N^{k-2}MHV}$ color-ordered partial amplitude in gauge theory as a linear combination of a basis of dimension $\\eulerian{n-3}{k-2}$. Here $\\eulerian{p}{q}$ denotes the $(p,q)$ Eulerian number. The coefficients of the expansion are independent of the helicities of the particles. This basis is a four-dimensional refinement of the $(n-3)!$-element BCJ basis which is valid in any number of dimensions. The construction uses a new kind of objects which we call {\\it scalar blocks}. Here we initiate the study of these objects. Scalar blocks provide an "${\\rm N^{k-2}MHV}$ sector" decomposition of a bi-adjoint scalar amplitude in four dimensions. As byproducts of the construction, we also find an intrinsically four-dimensional version of KLT relations for gravity amplitudes.

  1. The Functional Requirements and Design Basis for Information Barriers

    Energy Technology Data Exchange (ETDEWEB)

    Fuller, James L.

    2012-05-01

    This report summarizes the results of the Information Barrier Working Group workshop held at Sandia National Laboratory in Albuquerque, NM, February 2-4, 1999. This workshop was convened to establish the functional requirements associated with warhead radiation signature information barriers, to identify the major design elements of any such system or approach, and to identify a design basis for each of these major elements. Such information forms the general design basis to be used in designing, fabricating, and evaluating the complete integrated systems developed for specific purposes.

  2. Weak Basis Transformations and Texture Zeros in the Leptonic Sector

    CERN Document Server

    Branco, G C; Felipe, R Gonzalez; Serodio, H

    2007-01-01

    We investigate the physical meaning of some of the texture zeros which appear in most of the Ansatze on leptonic masses and their mixing. It is shown that starting from arbitrary lepton mass matrices and making suitable weak basis transformations one can obtain some of these sets of zeros, which therefore have no physical content. We then analyse four-zero texture Ansatze where the charged lepton and neutrino mass matrices have the same structure. The four texture zeros cannot be obtained simultaneously through weak basis transformations, so these Ansatze do have physical content. We show that they can be separated into four classes and study the physical implications of each class.

  3. EEG Source Reconstruction using Sparse Basis Function Representations

    DEFF Research Database (Denmark)

    Hansen, Sofie Therese; Hansen, Lars Kai

    2014-01-01

    State of the art performance of 3D EEG imaging is based on reconstruction using spatial basis function representations. In this work we augment the Variational Garrote (VG) approach for sparse approximation to incorporate spatial basis functions. As VG handles the bias variance trade-off with cross......-validation this approach is more automated than competing approaches such as Multiple Sparse Priors (Friston et al., 2008) or Champagne (Wipf et al., 2010) that require manual selection of noise level and auxiliary signal free data, respectively. Finally, we propose an unbiased estimator of the reproducibility...

  4. Fusion basis for lattice gauge theory and loop quantum gravity

    CERN Document Server

    Delcamp, Clement; Riello, Aldo

    2016-01-01

    We introduce a new basis for the gauge--invariant Hilbert space of lattice gauge theory and loop quantum gravity in $(2+1)$ dimensions, the fusion basis. In doing so, we shift the focus from the original lattice (or spin--network) structure directly to that of the magnetic (curvature) and electric (torsion) excitations themselves. These excitations are classified by the irreducible representations of the Drinfel'd double of the gauge group, and can be readily "fused" together by studying the tensor product of such representations. We will also describe in detail the ribbon operators that create and measure these excitations and make the quasi--local structure of the observable algebra explicit. Since the fusion basis allows for both magnetic and electric excitations from the onset, it turns out to be a precious tool for studying the large scale structure and coarse--graining flow of lattice gauge theories and loop quantum gravity. This is in neat contrast with the widely used spin--network basis, in which it ...

  5. 46 CFR 12.13-3 - Basis of documentary evidence.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Basis of documentary evidence. 12.13-3 Section 12.13-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN REQUIREMENTS FOR... documentary evidence. The Officer in Charge, Marine Inspection will issue such documentary evidence to...

  6. Gezondheidsclaims voor kruidenpreparaten op basis van Ginkgo biloba

    NARCIS (Netherlands)

    Pelgrom SMGJ; Fransen HP; Rompelberg CJM; de Rooij EK; Pronk MEJ; Baars AJ; de Kaste D; Verhagen H; SIR; CVG; KCF

    2007-01-01

    Er is onvoldoende bewijs voor drie geclaimde gezondheidseffecten bij het gebruik van kruidenpreparaten op basis van de Japanse notenboom Ginkgo biloba. Ook toont een analyse van 29 Ginkgo-preparaten aan dat het merendeel niet bevat wat op het etiket vermeld staat. Daarnaast kan bij de aanbevolen d

  7. The molecular basis of familial chronic lymphocytic leukemia

    OpenAIRE

    Crowther-Swanepoel, Dalemari; Houlston, Richard S.

    2009-01-01

    Our understanding of the genetic basis of chronic lymphocytic leukemia is only just starting to be recognized. This perspective article by Drs. Crowther-Swanepoel and Houlston provides an up-to-date review the molecular epidemiology of chronic lymphocytic leukemia, with emphasis on the integration of biology and genomics. See related paper on page 647.

  8. 42 CFR 422.300 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM MEDICARE ADVANTAGE PROGRAM Payments to Medicare Advantage Organizations § 422.300 Basis... for making payments to Medicare Advantage (MA) organizations offering local and regional MA...

  9. 42 CFR 409.40 - Basis, purpose, and scope.

    Science.gov (United States)

    2010-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM HOSPITAL INSURANCE BENEFITS Home Health Services Under Hospital Insurance § 409.40 Basis, purpose... respect to the requirements that must be met for Medicare payment to be made for home health...

  10. Identifying Psychopathy Subtypes on the Basis of Personality Structure

    Science.gov (United States)

    Hicks, Brian M.; Markon, Kristian E.; Patrick, Christopher J.; Krueger, Robert F.; Newman, Joseph P.

    2004-01-01

    The authors used model-based cluster analysis to identify subtypes of criminal psychopaths on the basis of differences in personality structure. Participants included 96 male prisoners diagnosed as psychopathic, using the Psychopathy Checklist Revised (PCL-R; R. D. Hare, 1991). Personality was assessed using the brief form of the Multidimensional…

  11. COMPOSITION BUILDING MATERIALS ON THE BASIS OF MODIFIED LIQUID OLIGODIENES

    OpenAIRE

    D. E. Barabash

    2010-01-01

    The results of elaboration of efficient building composites on the basis of modified oligodienes are presented. The basic propositions on design of ma-terial formulations for different purposes with consideration for the particu-larities of their use are given. The ways of improvement of technology of composites preparation subject to proposed operation conditions are sug-gested.

  12. 26 CFR 1.737-3 - Basis adjustments; Recovery rules.

    Science.gov (United States)

    2010-04-01

    ... depreciation (or other cost recovery) method (including first-year conventions) available to the partnership... distribution subject to section 737. (3) Method of adjustment. For the purpose of allocating the basis increase... effect under section 754. Any adjustments to the bases of partnership property (including...

  13. On the classification enhancement of radial basis function networks

    NARCIS (Netherlands)

    Ciftcioglu, O.; Durmisevic, S.; Sariyildiz, I.S.

    2001-01-01

    Artificial neural networks are powerfultools for analysing information expressed as data sets, which contain complex nonlinear relationships to be identified and classified. In particular radial basis function (RBF) neural networks have outstanding features for this. However, due to far reaching imp

  14. Direction-dependent learning approach for radial basis function networks.

    Science.gov (United States)

    Singla, Puneet; Subbarao, Kamesh; Junkins, John L

    2007-01-01

    Direction-dependent scaling, shaping, and rotation of Gaussian basis functions are introduced for maximal trend sensing with minimal parameter representations for input output approximation. It is shown that shaping and rotation of the radial basis functions helps in reducing the total number of function units required to approximate any given input-output data, while improving accuracy. Several alternate formulations that enforce minimal parameterization of the most general radial basis functions are presented. A novel "directed graph" based algorithm is introduced to facilitate intelligent direction based learning and adaptation of the parameters appearing in the radial basis function network. Further, a parameter estimation algorithm is incorporated to establish starting estimates for the model parameters using multiple windows of the input-output data. The efficacy of direction-dependent shaping and rotation in function approximation is evaluated by modifying the minimal resource allocating network and considering different test examples. The examples are drawn from recent literature to benchmark the new algorithm versus existing methods.

  15. Universal approximation by radial basis function networks of Delsarte translates.

    Science.gov (United States)

    Arteaga, Cristian; Marrero, Isabel

    2013-10-01

    We prove that, under certain mild conditions on the kernel function (or activation function), the family of radial basis function neural networks obtained by replacing the usual translation with the Delsarte one, and taking the same smoothing factor in all kernel nodes, has the universal approximation property.

  16. Creamod. Een infrastructuur voor smogmodellen op statistische basis

    NARCIS (Netherlands)

    Noordijk H; NLB

    2003-01-01

    The report describes software which has been developed in 1991 to construct smogmodels on a statistical basis. These smogmodels are in daily use for the smog outlook by RIVM. The software, Creamod, consists of a number of modules which are able to define, construct and evaluate statistical air quali

  17. Structural basis of cell-cell adhesion by NCAM

    DEFF Research Database (Denmark)

    Kasper, C; Rasmussen, H; Kastrup, Jette Sandholm Jensen;

    2000-01-01

    and learning. The 1.85 A crystal structure of the two N-terminal extracellular domains of NCAM reported here provides a structural basis for the homophilic interaction. The molecular packing of the two-domain structure reveals a cross shaped antiparallel dimer, and provides fundamental insight into trans...

  18. 7 CFR 70.10 - Basis of grading service.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) VOLUNTARY GRADING OF POULTRY PRODUCTS AND RABBIT PRODUCTS Grading of Poultry Products and Rabbit Products General § 70.10 Basis of... Poultry and Rabbits. However, grading service may be rendered with respect to products which are...

  19. The Legal Basis for the Regulation of Intercollegiate Sports.

    Science.gov (United States)

    Gerber, Ellen W.

    1979-01-01

    Through the requirements of Title IX and of various sports organizations, enforced by the Department of Health, Education, and Welfare and the courts, the external regulation of intercollegiate sports is a salient fact of college and university existence. The legal basis for regulation and some examples of enforcement are examined. (JMD)

  20. Cold Vacuum Drying (CVD) Facility Design Basis Accident Analysis Documentation

    Energy Technology Data Exchange (ETDEWEB)

    PIEPHO, M.G.

    1999-10-20

    This document provides the detailed accident analysis to support HNF-3553, Annex B, Spent Nuclear Fuel Project Final Safety Analysis Report, ''Cold Vacuum Drying Facility Final Safety Analysis Report (FSAR).'' All assumptions, parameters and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the FSAR.

  1. Canister storage building design basis accident analysis documentation

    Energy Technology Data Exchange (ETDEWEB)

    KOPELIC, S.D.

    1999-02-25

    This document provides the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report.

  2. Technical basis for the ITER-FEAT outline design

    International Nuclear Information System (INIS)

    This ITER EDA Documentation Series issue summarizes the results of the ITER Engineering Design Activities on the technical basis for the ITER-FEAT outline design. This issue also comprises some physical analysis activities as well as structure and goals of the Physics Expert Group activities

  3. Indicators as a Basis for Robust and Acceptable Fisheries Management

    OpenAIRE

    Nielsen, J.R.; Degnbol, P.; Reeves, S.; Hovgaard, H.

    2001-01-01

    Fisheries management is an activity that is implemented to achieve some objectives for fisheries as well as society. These objectives are not always clearly stated, but will generally emphasise the sustainability of the fish stocks, in some cases supplemented with insurance of food security and an economic basis for coastal communities.

  4. History and ecological basis for areawide pest management

    Science.gov (United States)

    The traditional approach to pest management is to treat the crop or commodity in a particular management unit before an economically significant infestation of the pest has developed. Determining the need to take corrective action is based on the economic threshold concept, which forms the basis of...

  5. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    International Nuclear Information System (INIS)

    This document provided the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report''. All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report

  6. THEORETICAL AND METHODOLOGICAL BASIS OF "DEVELOPING SURROUNDING" DEFINITION

    Directory of Open Access Journals (Sweden)

    Shalenkova M. K.

    2014-09-01

    Full Text Available The basis definition of "developing surrounding" is presented. The most important qualities, components and conditions of creation of the developing surrounding, such as material and technical, social and hygienic, ergonomic, psychological and pedagogical is considered. A great value of the developing surrounding in the educational institutions is revealed

  7. Entrepreneurial Creativity as a Convergent Basis for Teaching Business Communication

    Science.gov (United States)

    Grenci, Richard T.

    2012-01-01

    Of the "21st Century" business skills of communication, collaboration, creativity, and critical thinking, creativity arguably receives among the least explicit attention in traditional business core curricula. With that in mind, the context of entrepreneurial creativity is put forth as a basis for teaching business communication. By…

  8. THORETICAL AND ORGANIZATION BASIS OF ECO-CONTROLLING

    Directory of Open Access Journals (Sweden)

    N. Goncharenko

    2013-05-01

    Full Text Available Reviewed and improved theoretical and organizational basis for environmental controlling. The essence of eco-controlling was revealed and improved its definition, taking into account characteristics of the environmental management system. Objects, functions and tasks eco-controlling were defined, justified its principles and consistency of implementation.

  9. 42 CFR 426.100 - Basis and scope.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Basis and scope. 426.100 Section 426.100 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM REVIEW OF NATIONAL COVERAGE DETERMINATIONS AND LOCAL COVERAGE DETERMINATIONS...

  10. 44 CFR 67.6 - Basis of appeal.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Basis of appeal. 67.6 Section 67.6 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND... technically incorrect. Because scientific and technical correctness is often a matter of degree rather...

  11. 42 CFR 433.110 - Basis, purpose, and applicability.

    Science.gov (United States)

    2010-10-01

    ... and Information Retrieval Systems § 433.110 Basis, purpose, and applicability. (a) This subpart... information retrieval systems and for the operation of certain systems. Additional HHS regulations and CMS... mechanized claims processing and information retrieval system or if the system fails to meet...

  12. Solar Power Tower Design Basis Document, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    ZAVOICO,ALEXIS B.

    2001-07-01

    This report contains the design basis for a generic molten-salt solar power tower. A solar power tower uses a field of tracking mirrors (heliostats) that redirect sunlight on to a centrally located receiver mounted on top a tower, which absorbs the concentrated sunlight. Molten nitrate salt, pumped from a tank at ground level, absorbs the sunlight, heating it up to 565 C. The heated salt flows back to ground level into another tank where it is stored, then pumped through a steam generator to produce steam and make electricity. This report establishes a set of criteria upon which the next generation of solar power towers will be designed. The report contains detailed criteria for each of the major systems: Collector System, Receiver System, Thermal Storage System, Steam Generator System, Master Control System, and Electric Heat Tracing System. The Electric Power Generation System and Balance of Plant discussions are limited to interface requirements. This design basis builds on the extensive experience gained from the Solar Two project and includes potential design innovations that will improve reliability and lower technical risk. This design basis document is a living document and contains several areas that require trade-studies and design analysis to fully complete the design basis. Project- and site-specific conditions and requirements will also resolve open To Be Determined issues.

  13. The Neural Basis for Learning of Simple Motor Skills.

    Science.gov (United States)

    Lisberger, Stephen G.

    1988-01-01

    Discusses the vestibulo-ocular reflex (VOR) which is used to investigate the neural basis for motor learning in monkeys. Suggests organizing principles that may apply in forms of motor learning as a result of similarities among VOR and other motor systems. (Author/RT)

  14. Upwind design basis (WP4: offshore foundations and support structures)

    NARCIS (Netherlands)

    Fischer, T.; De Vries, W.E.; Schmidt, B.

    2010-01-01

    The presented design basis gives a summarized overview of relevant design properties for a later offshore wind turbine design procedures within work package 4. The described offshore site is located in the Dutch North Sea and has a water depth of 21m. Therefore it will be chosen as shallow site with

  15. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    International Nuclear Information System (INIS)

    This document provides the detailed accident analysis to support ''HNF-3553, Spent Nuclear Fuel Project Final Safety, Analysis Report, Annex A,'' ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report

  16. 42 CFR 411.32 - Basis for Medicare secondary payments.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Basis for Medicare secondary payments. 411.32 Section 411.32 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM EXCLUSIONS FROM MEDICARE AND LIMITATIONS ON MEDICARE PAYMENT Insurance...

  17. 42 CFR 411.110 - Basis for determination of nonconformance.

    Science.gov (United States)

    2010-10-01

    ... Section 411.110 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM EXCLUSIONS FROM MEDICARE AND LIMITATIONS ON MEDICARE PAYMENT Limitations on Payment for Services Covered Under Group Health Plans: General Provisions § 411.110 Basis...

  18. 7 CFR 54.1005 - Basis of service.

    Science.gov (United States)

    2010-01-01

    ... Sanitary Design and Fabrication of Equipment Used in the Slaughter, Processing, and Packaging of Livestock... of Equipment Used in the Slaughter, Processing, and Packaging of Livestock and Poultry Products... without discrimination on the basis of race, color, national origin, gender, religion, age,...

  19. The Prosodic Basis of the Tiberian Hebrew System of Accents.

    Science.gov (United States)

    Dresher, Bezalel Elan

    1994-01-01

    It is argued that the Tiberian system of accents that annotate the text of the Hebrew Bible has a prosodic basis. Tiberian representation can best be understood by integrating results of phonological, phonetic, and psycholinguistic research on prosodic structure. (93 references) (Author/LB)

  20. Optimized basis functions for slot antennas excited by coplanar waveguides

    NARCIS (Netherlands)

    Neto, A.; Maagt, P.de; Maci, S.

    2003-01-01

    A method is proposed for the analysis of slot antennas excited by coplanar waveguides. First, a standard integral equation for the continuity of the magnetic field is formulated. Then the appropriate equivalent magnetic currents of the method of moments are represented in terms of entire-domain basi

  1. A Basis for Powers of the Augmentation Ideal

    Institute of Scientific and Technical Information of China (English)

    M.M. Parmenter

    2001-01-01

    In this paper, an inductive method is given for constructing a Z-basis of the abelian group Δn(G) whenever G is a finite elementary abelian p-group,where Δ(G) is the augmentation ideal of the integral group ring ZG. This result is then applied to the problem of finding a presentation for Δn(G).

  2. Construction of `Wachspress Type' Rational Basis Functions over Rectangles

    Indian Academy of Sciences (India)

    P L Powar; S S Rana

    2000-02-01

    In the present paper, we have constructed rational basis functions of 0 class over rectangular elements with wider choice of denominator function. This construction yields additional number of interior nodes. Hence, extra nodal points and the flexibility of denominator function suggest better approximation.

  3. 7 CFR 42.105 - Basis for selection of sample.

    Science.gov (United States)

    2010-01-01

    ... contractor requests that corresponding single sampling plans be used. (2) Select the appropriate sample size... 7 Agriculture 2 2010-01-01 2010-01-01 false Basis for selection of sample. 42.105 Section 42.105 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE...

  4. 48 CFR 1426.7103-1 - Statutory basis.

    Science.gov (United States)

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS OTHER SOCIOECONOMIC PROGRAMS Minority Business Reports 1426.7103-1 Statutory basis... qualified minority business enterprises in awarding contracts under the Act and report annually to Congress... in programs carried out under the act. The Environmental Protection Agency has...

  5. 42 CFR 456.610 - Basis for determinations.

    Science.gov (United States)

    2010-10-01

    ... Facilities and Institutions for Mental Diseases § 456.610 Basis for determinations. In making the... psychiatric facilities, and mental hospitals; and (2) At least quarterly in ICFs; (c) Tests or observations of... malnutrition or dehydration; and (4) Apparent maintenance of maximum physical, mental, and psychosocial...

  6. 42 CFR 447.200 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis and purpose. 447.200 Section 447.200 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED..., economy, and quality of care....

  7. 42 CFR 447.300 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis and purpose. 447.300 Section 447.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED..., economy and quality of care. Section 447.371 implements section 1902(a)(15) of the Act, which...

  8. 42 CFR 447.250 - Basis and purpose.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis and purpose. 447.250 Section 447.250 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... requires that payments be consistent with efficiency, economy, and quality of care; (c) Sections 447.253...

  9. Solar Power Tower Design Basis Document, Revision 0; TOPICAL

    International Nuclear Information System (INIS)

    This report contains the design basis for a generic molten-salt solar power tower. A solar power tower uses a field of tracking mirrors (heliostats) that redirect sunlight on to a centrally located receiver mounted on top a tower, which absorbs the concentrated sunlight. Molten nitrate salt, pumped from a tank at ground level, absorbs the sunlight, heating it up to 565 C. The heated salt flows back to ground level into another tank where it is stored, then pumped through a steam generator to produce steam and make electricity. This report establishes a set of criteria upon which the next generation of solar power towers will be designed. The report contains detailed criteria for each of the major systems: Collector System, Receiver System, Thermal Storage System, Steam Generator System, Master Control System, and Electric Heat Tracing System. The Electric Power Generation System and Balance of Plant discussions are limited to interface requirements. This design basis builds on the extensive experience gained from the Solar Two project and includes potential design innovations that will improve reliability and lower technical risk. This design basis document is a living document and contains several areas that require trade-studies and design analysis to fully complete the design basis. Project- and site-specific conditions and requirements will also resolve open To Be Determined issues

  10. Role of Institutional Theory in Management Accounting Methodological Basis Formation

    OpenAIRE

    Iryna Sadovska

    2012-01-01

    The methodological basis of management accounting has been studied. In order to determine the management accounting methodologies the author has examined the classical approaches to understanding of its essence. The role of the new institutional economics in the process of its formation is revealed. A parallel between traditional and institutional approaches to the establishment and development of the management accounting methodology is drawn

  11. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    Energy Technology Data Exchange (ETDEWEB)

    CROWE, R.D.; PIEPHO, M.G.

    2000-03-23

    This document provided the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report''. All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report.

  12. Optimal Piecewise Linear Basis Functions in Two Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Brooks III, E D; Szoke, A

    2009-01-26

    We use a variational approach to optimize the center point coefficients associated with the piecewise linear basis functions introduced by Stone and Adams [1], for polygonal zones in two Cartesian dimensions. Our strategy provides optimal center point coefficients, as a function of the location of the center point, by minimizing the error induced when the basis function interpolation is used for the solution of the time independent diffusion equation within the polygonal zone. By using optimal center point coefficients, one expects to minimize the errors that occur when these basis functions are used to discretize diffusion equations, or transport equations in optically thick zones (where they approach the solution of the diffusion equation). Our optimal center point coefficients satisfy the requirements placed upon the basis functions for any location of the center point. We also find that the location of the center point can be optimized, but this requires numerical calculations. Curiously, the optimum center point location is independent of the values of the dependent variable on the corners only for quadrilaterals.

  13. Erosion Behavior of the Materials on Basis of Tungsten

    International Nuclear Information System (INIS)

    It is presented in this work the results of the erosion behavior examination of the materials on the basis of tungsten which have been produced with the use of different technologies (vacuum-arc coating deposition, chemical vapor deposition, hot pressing in a vacuum) under steady state Penning discharge plasma irradiation

  14. Canister storage building design basis accident analysis documentation

    International Nuclear Information System (INIS)

    This document provides the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report

  15. 49 CFR 525.7 - Basis for petition.

    Science.gov (United States)

    2010-10-01

    ... comply with that average fuel economy standard; and (4) Anticipated consumer demand in the United States... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EXEMPTIONS FROM AVERAGE FUEL ECONOMY STANDARDS § 525.7 Basis for... territory of the United States) by the petitioner in the second model year immediately preceding...

  16. Sparse approximation based on a random overcomplete basis

    Science.gov (United States)

    Nakanishi-Ohno, Yoshinori; Obuchi, Tomoyuki; Okada, Masato; Kabashima, Yoshiyuki

    2016-06-01

    We discuss a strategy of sparse approximation that is based on the use of an overcomplete basis, and evaluate its performance when a random matrix is used as this basis. A small combination of basis vectors is chosen from a given overcomplete basis, according to a given compression rate, such that they compactly represent the target data with as small a distortion as possible. As a selection method, we study the {{\\ell}0} - and {{\\ell}1} -based methods, which employ the exhaustive search and {{\\ell}1} -norm regularization techniques, respectively. The performance is assessed in terms of the trade-off relation between the distortion and the compression rate. First, we evaluate the performance analytically in the case that the methods are carried out ideally, using methods of statistical mechanics. The analytical result is then confirmed by performing numerical experiments on finite size systems, and extrapolating the results to the infinite-size limit. Our result clarifies the fact that the {{\\ell}0} -based method greatly outperforms the {{\\ell}1} -based one. An interesting outcome of our analysis is that any small value of distortion is achievable for any fixed compression rate r in the large-size limit of the overcomplete basis, for both the {{\\ell}0} - and {{\\ell}1} -based methods. The difference between these two methods is manifested in the size of the overcomplete basis that is required in order to achieve the desired value for the distortion. As the desired distortion decreases, the required size grows in a polynomial and an exponential manners for the {{\\ell}0} - and {{\\ell}1} -based methods, respectively. Second, we examine the practical performances of two well-known algorithms, orthogonal matching pursuit and approximate message passing, when they are used to execute the {{\\ell}0} - and {{\\ell}1} -based methods, respectively. Our examination shows that orthogonal matching pursuit achieves a much better performance than the exact execution of

  17. Resilient Control Systems Practical Metrics Basis for Defining Mission Impact

    Energy Technology Data Exchange (ETDEWEB)

    Craig G. Rieger

    2014-08-01

    "Resilience” describes how systems operate at an acceptable level of normalcy despite disturbances or threats. In this paper we first consider the cognitive, cyber-physical interdependencies inherent in critical infrastructure systems and how resilience differs from reliability to mitigate these risks. Terminology and metrics basis are provided to integrate the cognitive, cyber-physical aspects that should be considered when defining solutions for resilience. A practical approach is taken to roll this metrics basis up to system integrity and business case metrics that establish “proper operation” and “impact.” A notional chemical processing plant is the use case for demonstrating how the system integrity metrics can be applied to establish performance, and

  18. Rationalization of foundry processes on the basis of simulation experiment

    Directory of Open Access Journals (Sweden)

    S. Kukla

    2008-10-01

    Full Text Available The paper presents results of research obtained on the basis of simulation experiment, whose aim was to analyze the performance of cast iron foundry. A simulation model of automobile industry foundry was made. The course of the following processes was analyzedin a computer model: preparation of liquid cast iron, forming and filling the moulds, cooling and stamping the castings, cleaning andfinishing treatment. The sheets of multi-criterion evaluation were prepared, where criteria and variants were assessed by meansof subjective point evaluation and fuzzy character evaluation. The paper presents an analysis example of finishing activities of castings realized in foundry on traditional machines and efficient presses and in cooperation. On the basis of reports from a simulation experiment information was achieved related to activities’ duration, load of accessible resources, the problems of storage and transport, bottle necks in the system and appearing queues in from of workplaces. The research used a universal modelling and simulation packet for productionsystems - ARENA.

  19. AN IMPROVED RADIAL BASIS FUNCTION BASED METHOD FOR IMAGE WARPING

    Institute of Scientific and Technical Information of China (English)

    Nie Xuan; Zhao Rongchun; Zhang Cheng; Zhang Xiaoyan

    2005-01-01

    A new image warping method is proposed in this letter, which can warp a given image by some manual defined features. Based on the radial basis interpolation function algorithm, the proposed method can transform the original optimized problem into nonsingular linear problem by adding one-order term and affine differentiable condition. This linear system can get the steady unique solution by choosing suitable kernel function. Furthermore, the proposed method demonstrates how to set up the radial basis function in the target image so as to achieve supports to adopt the backward re-sampling technology accordingly which could gain the very slippery warping image. Theexperimental result shows that the proposed method can implement smooth and gradual image warping with multi-anchor points' accurate interpolation.

  20. Learning and generalization in radial basis function networks.

    Science.gov (United States)

    Freeman, J A; Saad, D

    1995-09-01

    The two-layer radial basis function network, with fixed centers of the basis functions, is analyzed within a stochastic training paradigm. Various definitions of generalization error are considered, and two such definitions are employed in deriving generic learning curves and generalization properties, both with and without a weight decay term. The generalization error is shown analytically to be related to the evidence and, via the evidence, to the prediction error and free energy. The generalization behavior is explored; the generic learning curve is found to be inversely proportional to the number of training pairs presented. Optimization of training is considered by minimizing the generalization error with respect to the free parameters of the training algorithms. Finally, the effect of the joint activations between hidden-layer units is examined and shown to speed training.

  1. Relevant Assumptions at the basis of the UMAE uncertainty methodology

    International Nuclear Information System (INIS)

    This paper deals with preliminary results of the application of UMAE (Uncertainty Methodology based upon Accuracy Extrapolation) uncertainty procedure to the Uncertainty Methods Study (UMS) proposed by OECD/CSNI. The UMAE allows the evaluation of the error made by a system thermalhydraulic code when predicting a nuclear power plant transient scenario. The UMS is an international activity proposed with the aim of comparing the basic assumptions and the results produced by five uncertainty methodologies. The transient adopted as the object of the analysis is a small break LOCA performed in the Japanese Large Scale Test Facility (LSTF) previously adopted for International Standard Problem 26. The analysis of ten experiments performed in differently scaled facilities have been used as a basis for extrapolation of the accuracy. The hypothesis at the basis of the methodology and the main steps are discussed. (author)

  2. Coulomb Sturmians as a basis for molecular calculations

    DEFF Research Database (Denmark)

    Avery, John Scales; Avery, James Emil

    2012-01-01

    Almost all modern quantum chemistry programs use Gaussian basis sets even though Gaussians cannot accurately represent the cusp at atomic nuclei, nor can they represent the slow decay of the wave function at large distances. The reason that Gaussians dominate quantum chemistry today is the great ...... of hyperspherical harmonics. For the remaining many-centre integrals, Coulomb Sturmians are shown to have advantages over other ETOs. Pilot calculations are performed on N-electron molecules using the Generalized Sturmian Method....... mathematical difficulty of evaluating interelectron repulsion integrals when exponential-type orbitals (ETOs) are used. In this paper we show that when many-centre Coulomb Sturmian ETOs are used as a basis, the most important integrals can be evaluated rapidly and accurately by means of the theory...

  3. Two Normal Basis Multiplication Algorithms for GF(2n)

    Institute of Scientific and Technical Information of China (English)

    FAN Haining; LIU Duo; DAI Yiqi

    2006-01-01

    For software implementations, word-level normal basis multiplication algorithms utilize the full data-path of the processor, and hence are more efficient than the bit-level multiplication algorithm presented in the IEEE standard P1363-2000. In this paper, two word-level normal basis multiplication algorithms are proposed for GF(2n). The first algorithm is suitable for high complexity normal bases, while the second algorithm is fast for type-Ⅰ optimal normal bases and low complexity normal bases. Theoretical analyses and experimental results both indicate that the presented algorithms are efficient in GF(2233), GF(2283), GF(2409),and GF(2571), which are four of the five binary fields recommended by the National Institute of Standards and Technology (NIST) for the elliptic curve digital signature algorithm (ECDSA) applications.

  4. Basis for NGNP Reactor Design Down-Selection

    Energy Technology Data Exchange (ETDEWEB)

    L.E. Demick

    2011-11-01

    The purpose of this paper is to identify the extent of technology development, design and licensing maturity anticipated to be required to credibly identify differences that could make a technical choice practical between the prismatic and pebble bed reactor designs. This paper does not address a business decision based on the economics, business model and resulting business case since these will vary based on the reactor application. The selection of the type of reactor, the module ratings, the number of modules, the configuration of the balance of plant and other design selections will be made on the basis of optimizing the Business Case for the application. These are not decisions that can be made on a generic basis.

  5. Basis for NGNP Reactor Design Down-Selection

    Energy Technology Data Exchange (ETDEWEB)

    L.E. Demick

    2010-08-01

    The purpose of this paper is to identify the extent of technology development, design and licensing maturity anticipated to be required to credibly identify differences that could make a technical choice practical between the prismatic and pebble bed reactor designs. This paper does not address a business decision based on the economics, business model and resulting business case since these will vary based on the reactor application. The selection of the type of reactor, the module ratings, the number of modules, the configuration of the balance of plant and other design selections will be made on the basis of optimizing the Business Case for the application. These are not decisions that can be made on a generic basis.

  6. [Physiological Basis of Pain Mechanisms for Pain Management].

    Science.gov (United States)

    Kawamata, Mikito

    2016-05-01

    Physician anesthesiologists should ensure a future leadership position in perioperative medicine and pain medicine. In order to establish the missions, anesthesiologists need to know how to relieve pain in surgical patients, critically ill patients and patients with cancer and non-cancer chronic pain. Thus, anesthesiologists should realize physiology of pain representation from pain management I will review physiological basis of pain mechanisms in this manuscript which includes 1) evolutional aspect of pain perception, 2) transduction of noxious stimuli, 3) the types of nociceptors and conduction of noxious stimuli, 4) the ascending pathway of pain and central modulation of pain, 5) the descending inhibitory pain system, and 6) various types of pain. Finally, anesthesiologists should manage pain from physiological basis of pain mechanisms. PMID:27319092

  7. Libcint: An efficient general integral library for Gaussian basis functions

    CERN Document Server

    Sun, Qiming

    2014-01-01

    An efficient integral library Libcint was designed to automatically implement general integrals for Gaussian-type scalar and spinor basis functions. The library can handle arbitrary integral expressions on top of $\\mathbf{p}$, $\\mathbf{r}$ and $\\sigma$ operators with one-electron overlap and nuclear attraction, two-electron Coulomb and Gaunt operators. Using a symbolic algebra tool, new integrals are derived and translated to C code programmatically. The generated integrals can be used in various types of molecular properties. In the present work, we computed the analytical gradients and NMR shielding constants at both non-relativistic and four-component relativistic Hartree-Fock level to demonstrate the capability of the integral library. Due to the use of kinetically balanced basis and gauge including atomic orbitals, the relativistic analytical gradients and shielding constants requires the integral library to handle the fifth-order electron repulsion integral derivatives. The generality of the integral li...

  8. Design-Load Basis for LANL Structures, Systems, and Components

    Energy Technology Data Exchange (ETDEWEB)

    I. Cuesta

    2004-09-01

    This document supports the recommendations in the Los Alamos National Laboratory (LANL) Engineering Standard Manual (ESM), Chapter 5--Structural providing the basis for the loads, analysis procedures, and codes to be used in the ESM. It also provides the justification for eliminating the loads to be considered in design, and evidence that the design basis loads are appropriate and consistent with the graded approach required by the Department of Energy (DOE) Code of Federal Regulation Nuclear Safety Management, 10, Part 830. This document focuses on (1) the primary and secondary natural phenomena hazards listed in DOE-G-420.1-2, Appendix C, (2) additional loads not related to natural phenomena hazards, and (3) the design loads on structures during construction.

  9. Epidemiologic measures of risk as a basis for legal compensation

    International Nuclear Information System (INIS)

    The scientific basis for compensation of persons developing cancer who have a documented history of exposure to radiation or other carcinogens is an important legal issue. The measure Relative Attributable Risk (RAR) has been proposed as a basis for determining eligibility for compensation. The purpose of this report is to present results of an analysis of the magnitude and sources of uncertainty in the RAR measure. The range of 1/106/rad-year to 6/106/rad-year was chosen as a reasonable range of excess-risk estimates for thyroid cancer based on published estimates. The use of such a range in risk estimates produces very wide variability in RAR estimates. Uncertainty in underlying incidence levels and in dosimetry are other major factors contributing to large variability in estimated RAR levels

  10. Applications of Basis Light-Front Quantization to QED

    CERN Document Server

    Vary, James P; Ilderton, Anton; Honkanen, Heli; Maris, Pieter; Brodsky, Stanley J

    2014-01-01

    Hamiltonian light-front quantum field theory provides a framework for calculating both static and dynamic properties of strongly interacting relativistic systems. Invariant masses, correlated parton amplitudes and time-dependent scattering amplitudes, possibly with strong external time-dependent fields, represent a few of the important applications. By choosing the light-front gauge and adopting an orthonormal basis function representation, we obtain a large, sparse, Hamiltonian matrix eigenvalue problem for mass eigenstates that we solve by adapting ab initio no-core methods of nuclear many-body theory. In the continuum limit, the infinite matrix limit, we recover full covariance. Guided by the symmetries of light-front quantized theory, we adopt a two-dimensional harmonic oscillator basis for transverse modes that corresponds with eigensolutions of the soft-wall anti-de Sitter/quantum chromodynamics (AdS/QCD) model obtained from light-front holography. We outline our approach and present results for non-lin...

  11. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    Energy Technology Data Exchange (ETDEWEB)

    CROWE, R.D.

    1999-09-09

    This document provides the detailed accident analysis to support ''HNF-3553, Spent Nuclear Fuel Project Final Safety, Analysis Report, Annex A,'' ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report.

  12. MANAGEMENT OF PHARMACY CHAIN ON THE BASIS OF OUTSOURCING

    OpenAIRE

    I. A. Dzhuparova

    2015-01-01

    The article studies the problems of development of methods of the outsourcing reasoning of a certain business process of pharmacy chains considering the risk on the basis of the system analysis, expert survey, theory of probability, mathematical statistics. Business processes of the pharmacy chain for outsourcing have been indicated. We have offered an “index of outsourcing reasonability” for qualitative evaluation of business processes implementation.

  13. Application of discrete basis set methods to the Dirac equation

    International Nuclear Information System (INIS)

    The basis sets described provide a convenient method for the direct relativistic calculation of a wide variety of atomic properties. Results have been obtained for the ground state polarizability, and the 2s/sub 1/2/-1s/sub 1/2/ two-photon transition rate of hydrogenic ions. The latter calculation includes all retardation effects and contributions from higher photon multipoles

  14. Feynman-Goldstone diagrams in a time-dependent basis

    Energy Technology Data Exchange (ETDEWEB)

    Baranger, M.; Zahed, I.

    1984-03-01

    A generalization of many-fermion Feynman-Goldstone diagrams is derived based on a time-dependent unperturbed Hamiltonian along with a time-dependent reference state. In lowest order, the time-dependent Hartree-Fock equations follow immediately from the same arguments which lead to static Hartree-Fock when the basis is time independent. Systematic corrections to the time-dependent Hartree-Fock mean-field approximation are obtained through higher order diagrams.

  15. Correlated basis theory of nucleon optical potential in nuclear matter

    Energy Technology Data Exchange (ETDEWEB)

    Fantoni, S.; Friman, B.L.; Pandharipande, V.R.

    1983-01-01

    A brief, simple outline is given of correlated basis perturbation theory and the criterion is discussed for choosing the correlation operator. Next the choice of the nuclear Hamiltonian is discussed and results obtained for nuclear binding energies, and the real and imaginary parts of the nucleon optical potential in nuclear matter are given. The effect of the nonlocality of the real part of the optical potential on the imaginary part is also discussed. 19 references, 7 figures, 1 table.

  16. Certified reduced basis methods for parametrized partial differential equations

    CERN Document Server

    Hesthaven, Jan S; Stamm, Benjamin

    2016-01-01

    This book provides a thorough introduction to the mathematical and algorithmic aspects of certified reduced basis methods for parametrized partial differential equations. Central aspects ranging from model construction, error estimation and computational efficiency to empirical interpolation methods are discussed in detail for coercive problems. More advanced aspects associated with time-dependent problems, non-compliant and non-coercive problems and applications with geometric variation are also discussed as examples.

  17. Conventional modeling of the multilayer perceptron using polynomial basis functions

    Science.gov (United States)

    Chen, Mu-Song; Manry, Michael T.

    1993-01-01

    A technique for modeling the multilayer perceptron (MLP) neural network, in which input and hidden units are represented by polynomial basis functions (PBFs), is presented. The MLP output is expressed as a linear combination of the PBFs and can therefore be expressed as a polynomial function of its inputs. Thus, the MLP is isomorphic to conventional polynomial discriminant classifiers or Volterra filters. The modeling technique was successfully applied to several trained MLP networks.

  18. Organisms modeling: The question of radial basis function networks

    Directory of Open Access Journals (Sweden)

    Muzy Alexandre

    2014-01-01

    Full Text Available There exists usually a gap between bio-inspired computational techniques and what biologists can do with these techniques in their current researches. Although biology is the root of system-theory and artifical neural networks, computer scientists are tempted to build their own systems independently of biological issues. This publication is a first-step re-evalution of an usual machine learning technique (radial basis funtion(RBF networks in the context of systems and biological reactive organisms.

  19. Combining regression trees and radial basis function networks.

    Science.gov (United States)

    Orr, M; Hallam, J; Takezawa, K; Murra, A; Ninomiya, S; Oide, M; Leonard, T

    2000-12-01

    We describe a method for non-parametric regression which combines regression trees with radial basis function networks. The method is similar to that of Kubat, who was first to suggest such a combination, but has some significant improvements. We demonstrate the features of the new method, compare its performance with other methods on DELVE data sets and apply it to a real world problem involving the classification of soybean plants from digital images.

  20. DEVELOPMENT OF COMPOSITION OF INFUSION MEDICATION ON BASIS OF MOXIFLOXACIN

    OpenAIRE

    Almakaeva L.G.; Begunova N.V.; Naumenok L.G.; Dolya V.G.; Almakaev М.S.

    2015-01-01

    Application of fluoroquinolones covers by experience of treatment more than 800 million patients, and presently they are one of basic classes in the antimicrobial arsenal of practical medicine. Such achievements became possible after the clear understanding of intercommunication of structure and activity of molecules of this class of antibiotics. This knowledge became the basis for the synthesis of new derivatives with a wide range, powerful activity and improved pharm...

  1. Country Segmentation On The Basis Of Global Purchasing Patterns

    OpenAIRE

    Frear, C R; Alguire, M S; Metcalf, L E

    1994-01-01

    Companies that successfully incorporate global sourcing into their global marketing strategies enhance their abilities to provide their customers with quality products at acceptable prices. To a large extent, an effective global marketing strategy depends on a firm's ability to segment its global markets. Previous studies addressed country segmentation on the basis of clustering a group of countries by an array of macroeconomic factors. These studies focused their attention on segmenting coun...

  2. Social parasitism and the molecular basis of phenotypic evolution

    Directory of Open Access Journals (Sweden)

    Alessandro eCini

    2015-02-01

    Full Text Available Contrasting phenotypes arise from similar genomes through a combination of losses, gains, co-option and modifications of inherited genomic material. Understanding the molecular basis of this phenotypic diversity is a fundamental challenge in modern evolutionary biology. Comparisons of the genes and their expression patterns underlying traits in pairs of closely related species offer an unrivalled opportunity to evaluate the extent to which genomic material is reorganised to produce novel traits. Advances in molecular methods now allow us to dissect the molecular machinery underlying phenotypic diversity in almost any organism, from single-celled organisms to the most complex vertebrates. Here we discuss how comparisons of social parasites and their free-living hosts may provide unique insights into the molecular basis of phenotypic evolution. Social parasites evolve from a social ancestor and are specialised to exploit the socially acquired resources of their closely-related, free-living social host. Molecular comparisons of such species pairs can reveal how genomic material is re-organised in the loss of ancestral traits (i.e. of free-living traits in the parasites and the gain of new ones (i.e. specialist traits required for a parasitic lifestyle. We define hypotheses on the molecular basis of phenotypes in the evolution of social parasitism and discuss their wider application in understanding the molecular basis of phenotypic diversity within the theoretical framework of phenotypic plasticity and shifting reaction norms. Currently there are no data available to test these hypotheses, and so we also provide some proof of concept data for our conceptual model using the paper wasp social parasite-host system (Polistes sulcifer - Polistes dominula. This conceptual framework and first empirical data provide a spring-board for directing future genomic analyses on exploiting social parasites as a route to understanding the evolution of phenotypic

  3. Implementation of Radial Basis Function Neural Network for Image Steganalysis

    OpenAIRE

    Sambasiva Rao Baragada; S. Ramakrishna; M.S. Rao; S. Purushothaman

    2008-01-01

    Steganographic tools and techniques are becoming more potential and widespread. Illegal use of steganography poses serious challenges to the law enforcement agencies. Limited work has been carried out on supervised steganalysis using neural network as a classifier. We present a combined method of identifying the presence of covert information in a carrier image using fisher’s linear discriminant (FLD) function followed by the radial basis function (RBF). Experiments show promising resu...

  4. Strategies of transformation of libraries informational technological basis

    OpenAIRE

    Tavalbekh A.

    2010-01-01

    Questions of evolution of informational technologies in library sphere are considered. They are providing necessary level of satisfaction of society needs in information and knowledge. Substantial sights of technological progression are becoming changes of ways of influence on information in any form and its complex unification. Development staging of technological basis of library from learning of computer, information communicational technologies to multimedia technologies is observing. Vec...

  5. Essence of Personnel Motivation as the Basis of Enterprise Development

    OpenAIRE

    Vynogradova Olena V.; Piligrim Kateryna I.

    2013-01-01

    The article reveals essence of the “motivation” notion from the point of view of management theories on the basis of the informal theory and procedural theory, as the content and process; studies scientific approaches with respect to identification of the goal of development of motivation with specification of harmonious and non-harmonious with the enterprise development; reveals the essence of personnel motivation with specification of its role in the process of enterprise development, provi...

  6. Advances in the physics basis for the European DEMO design

    Science.gov (United States)

    Wenninger, R.; Arbeiter, F.; Aubert, J.; Aho-Mantila, L.; Albanese, R.; Ambrosino, R.; Angioni, C.; Artaud, J.-F.; Bernert, M.; Fable, E.; Fasoli, A.; Federici, G.; Garcia, J.; Giruzzi, G.; Jenko, F.; Maget, P.; Mattei, M.; Maviglia, F.; Poli, E.; Ramogida, G.; Reux, C.; Schneider, M.; Sieglin, B.; Villone, F.; Wischmeier, M.; Zohm, H.

    2015-06-01

    In the European fusion roadmap, ITER is followed by a demonstration fusion power reactor (DEMO), for which a conceptual design is under development. This paper reports the first results of a coherent effort to develop the relevant physics knowledge for that (DEMO Physics Basis), carried out by European experts. The program currently includes investigations in the areas of scenario modeling, transport, MHD, heating & current drive, fast particles, plasma wall interaction and disruptions.

  7. Quadrupole collective variables in the natural Cartan-Weyl basis

    OpenAIRE

    De Baerdemacker, S.; Heyde, K.; Hellemans, V.

    2007-01-01

    The matrix elements of the quadrupole collective variables, emerging from collective nuclear models, are calculated in the natural Cartan-Weyl basis of O(5) which is a subgroup of a covering $SU(1,1)\\times O(5)$ structure. Making use of an intermediate set method, explicit expressions of the matrix elements are obtained in a pure algebraic way, fixing the $\\gamma$-rotational structure of collective quadrupole models.

  8. Experimental investigations on the basis for intellectual property rights.

    Science.gov (United States)

    Fast, Anne A; Olson, Kristina R; Mandel, Gregory N

    2016-08-01

    Lay people routinely misunderstand or do not obey laws protecting intellectual property (IP), leading to a variety of (largely unsuccessful) efforts by policymakers, IP owners, and researchers to change those beliefs and behaviors. The current work tests a new approach, inquiring whether lay people's views about IP protection can be modified by arguments concerning the basis for IP rights. Across 2 experiments, 572 adults (recruited through Amazon Mechanical Turk) read 1 of 6 arguments about the basis for IP protection (incentives, natural rights, expressive rights, plagiarism, commons, or no argument). Participants then reported their general support for IP protection. Participants also reported their evaluations of 2 scenarios that involved infringement of IP rights, including cases in which there were mitigating experiences (e.g., the copier acknowledged the original source), and completed several demographic questions. Three primary findings emerged: (a) exposure to the importance of the public commons (and to a lesser extent, exposure to the argument that plagiarism is the basis of IP protection) led participants to become less supportive of IP protection than the incentives, natural rights, expressive rights, and control conditions; (b) people believed that infringement was more acceptable if the infringer acknowledged the original creator of the work; and (c) older adults and women were especially likely to see infringement as problematic. These findings illustrate several ways in which lay beliefs are at odds with legal doctrine, and suggest that people's views about IP protection can be shaped in certain ways by learning the basis for IP rights. (PsycINFO Database Record PMID:27149291

  9. Application of the Characteristic Basis Function Method Using CUDA

    Directory of Open Access Journals (Sweden)

    Juan Ignacio Pérez

    2014-01-01

    Full Text Available The characteristic basis function method (CBFM is a popular technique for efficiently solving the method of moments (MoM matrix equations. In this work, we address the adaptation of this method to a relatively new computing infrastructure provided by NVIDIA, the Compute Unified Device Architecture (CUDA, and take into account some of the limitations which appear when the geometry under analysis becomes too big to fit into the Graphics Processing Unit’s (GPU’s memory.

  10. Selection of the design basis leak for LMFBR steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, R A; Pfefferlen, H C; Roberts, J M; Sane, J O

    1977-11-01

    Steam generator tube failure mechanisms that have been observed in experiments or that have been postulated are discussed. The DBL for CRBRP and a proposed DBL for future large LMFBR steam generators are described. Safety considerations and philosophy in selection of Design Basis Leaks (DBL) are presented. A discussion of the Large Leak Test Rig (LLTR) Series II program support of the DBL selection for future large LMFBR steam generators is included.

  11. Genetic influences on the neural basis of social cognition

    OpenAIRE

    Skuse, David

    2006-01-01

    The neural basis of social cognition has been the subject of intensive research in both human and non-human primates. Exciting, provocative and yet consistent findings are emerging. A major focus of interest is the role of efferent and afferent connectivity between the amygdala and the neocortical brain regions, now believed to be critical for the processing of social and emotional perceptions. One possible component is a subcortical neural pathway, which permits rapid and preconscious proces...

  12. MANAGER PRINCIPLES AS BASIS OF MANAGEMENT STYLE TRANSFORMATION

    OpenAIRE

    R. A. Kopytov

    2011-01-01

    The paper considers an approach which is based on non-conventional mechanisms of management style formation. The preset level of sustainable management is maintained by self-organized environment created in the process of management style transformation in efficient management principles. Their efficiency is checked within an adaptive algorithm. The algorithm is developed on the basis of combination of evaluative tools  and base of operational  proves. The operating algorithm capability is te...

  13. Experimental investigations on the basis for intellectual property rights.

    Science.gov (United States)

    Fast, Anne A; Olson, Kristina R; Mandel, Gregory N

    2016-08-01

    Lay people routinely misunderstand or do not obey laws protecting intellectual property (IP), leading to a variety of (largely unsuccessful) efforts by policymakers, IP owners, and researchers to change those beliefs and behaviors. The current work tests a new approach, inquiring whether lay people's views about IP protection can be modified by arguments concerning the basis for IP rights. Across 2 experiments, 572 adults (recruited through Amazon Mechanical Turk) read 1 of 6 arguments about the basis for IP protection (incentives, natural rights, expressive rights, plagiarism, commons, or no argument). Participants then reported their general support for IP protection. Participants also reported their evaluations of 2 scenarios that involved infringement of IP rights, including cases in which there were mitigating experiences (e.g., the copier acknowledged the original source), and completed several demographic questions. Three primary findings emerged: (a) exposure to the importance of the public commons (and to a lesser extent, exposure to the argument that plagiarism is the basis of IP protection) led participants to become less supportive of IP protection than the incentives, natural rights, expressive rights, and control conditions; (b) people believed that infringement was more acceptable if the infringer acknowledged the original creator of the work; and (c) older adults and women were especially likely to see infringement as problematic. These findings illustrate several ways in which lay beliefs are at odds with legal doctrine, and suggest that people's views about IP protection can be shaped in certain ways by learning the basis for IP rights. (PsycINFO Database Record

  14. Attitude toward death and the basie structure of personality.

    OpenAIRE

    Piotrowski, Jarosław; Żemojtel-Piotrowska, Magdalena

    2004-01-01

    In the present study, two attitudes toward death are concerned: the Anxiety and the Fascination. The Death Anxiety referred to the fear of death in the generał meaning. The Death Fascination contained the cognitive interest in death and dying and the acceptance of committing suicide by examined persons. Among 149 subjects were tested the relation between attitudes toward death, the Big Five model by Costa and McCrae and the basie components of temperament postulated by Strelau. The regression...

  15. Operators of the scattering theory in discrete basis

    International Nuclear Information System (INIS)

    In the work the convenient finite-dimensional approximations for basic operators of the scattering theory (Green operator and out-mass T-matrix) on the basis of general idea about continuum discretization with help of limited in the space own Eigen differentials of accurate scattering wave functions (stationary wave packages) were constructed. Obtained presentations for scattering operators could found a wide application in diverse fields of quantum collision theory

  16. Electronic structure basis for the titanic magnetoresistance in WTe$_2$

    OpenAIRE

    Pletikosić, I.; Ali, Mazhar N.; Fedorov, A; Cava, R. J.; Valla, T.

    2014-01-01

    The electronic structure basis of the extremely large magnetoresistance in layered non-magnetic tungsten ditelluride has been investigated by angle-resolved photoelectron spectroscopy. Hole and electron pockets of approximately the same size were found at the Fermi level, suggesting that carrier compensation should be considered the primary source of the effect. The material exhibits a highly anisotropic, quasi one-dimensional Fermi surface from which the pronounced anisotropy of the magnetor...

  17. A Reduced Basis Method for the Simulation of American Options

    CERN Document Server

    Haasdonk, Bernard; Wohlmuth, Barbara

    2012-01-01

    We present a reduced basis method for the simulation of American option pricing. To tackle this model numerically, we formulate the problem in terms of a time dependent variational inequality. Characteristic ingredients are a POD-greedy and an angle-greedy procedure for the construction of the primal and dual reduced spaces. Numerical examples are provided, illustrating the approximation quality and convergence of our approach.

  18. Basis properties of eigenfunctions of nonlinear Sturm-Liouville problems

    Directory of Open Access Journals (Sweden)

    Peter E. Zhidkov

    2000-04-01

    Full Text Available We consider three nonlinear eigenvalue problems that consist of $$-y''+f(y^2y=lambda y$$ with one of the following boundary conditions: $$displaylines{ y(0=y(1=0 quad y'(0=p ,,cr y'(0=y(1=0 quad y(0=p,, cr y'(0=y'(1=0 quad y(0=p,, }$$ where $p$ is a positive constant. Under smoothness and monotonicity conditions on $f$, we show the existence and uniqueness of a sequence of eigenvalues ${lambda _n}$ and corresponding eigenfunctions ${y_n}$ such that $y_n(x$ has precisely $n$ roots in the interval $(0,1$, where $n=0,1,2,dots$. For the first boundary condition, we show that ${y_n}$ is a basis and that ${y_n/|y_n|}$ is a Riesz basis in the space $L_2(0,1$. For the second and third boundary conditions, we show that ${y_n}$ is a Riesz basis.

  19. Design basis tropical cyclone for nuclear power plants

    International Nuclear Information System (INIS)

    The general characteristics of tropical cyclones are discussed in this Safety Guide, with particular emphasis on their pressure and wind structures in the light of available data. General methods are given for the evaluation of the relevant parameters of a Probable Maximum Tropical Cyclone (PMTC), which can be used as the Design Basis Tropical Cyclone (DBTC); these parameters then serve as inputs for the derivation of a design basis surge and a design basis wind. A possible method is also given for the evaluation of the PMTC pressure and wind field based on an approach valid primarily for a particular region. This method depends on the results of a theoretical study on the tropical cyclone structure and makes use of a large amount of data, including aircraft reconnaissance observations for 170 most intense tropical cyclones near the coast of Japan, Taiwan and the Philippines for the period 1960-1974, as well as detailed analyses of all the extreme storms along the Gulf of Mexico and the east coast of the USA during 1900-1978, for the determination of the necessary parameters

  20. Neural basis of interpersonal traits in neurodegenerative diseases.

    Science.gov (United States)

    Sollberger, Marc; Stanley, Christine M; Wilson, Stephen M; Gyurak, Anett; Beckman, Victoria; Growdon, Matthew; Jang, Jung; Weiner, Michael W; Miller, Bruce L; Rankin, Katherine P

    2009-11-01

    Several functional and structural imaging studies have investigated the neural basis of personality in healthy adults, but human lesions studies are scarce. Personality changes are a common symptom in patients with neurodegenerative diseases like frontotemporal dementia (FTD) and semantic dementia (SD), allowing a unique window into the neural basis of personality. In this study, we used the Interpersonal Adjective Scales to investigate the structural basis of eight interpersonal traits (dominance, arrogance, coldness, introversion, submissiveness, ingenuousness, warmth, and extraversion) in 257 subjects: 214 patients with neurodegenerative diseases such as FTD, SD, progressive nonfluent aphasia, Alzheimer's disease, amnestic mild cognitive impairment, corticobasal degeneration, and progressive supranuclear palsy and 43 healthy elderly people. Measures of interpersonal traits were correlated with regional atrophy pattern using voxel-based morphometry (VBM) analysis of structural MR images. Interpersonal traits mapped onto distinct brain regions depending on the degree to which they involved agency and affiliation. Interpersonal traits high in agency related to left dorsolateral prefrontal and left lateral frontopolar regions, whereas interpersonal traits high in affiliation related to right ventromedial prefrontal and right anteromedial temporal regions. Consistent with the existing literature on neural networks underlying social cognition, these results indicate that brain regions related to externally focused, executive control-related processes underlie agentic interpersonal traits such as dominance, whereas brain regions related to internally focused, emotion- and reward-related processes underlie affiliative interpersonal traits such as warmth. In addition, these findings indicate that interpersonal traits are subserved by complex neural networks rather than discrete anatomic areas.

  1. Broadening soybean genetic basis in the northeast of China

    Institute of Scientific and Technical Information of China (English)

    WangJinling

    1994-01-01

    The bottle neek of advancement of soybean breeding inthe Northeast of China is the lack of genetic diversity of the parents used in cross breeding.In order to overcome this constrained condition,under the sponsorship of China National Committe of Natural Science Fundation,a network project with the topic"Broadening and Improving of the Genetic Basis of the Northeast Soybeans" was established in 1990,and the Northeast agricultural University was apointed to take charge of the project.The project included the following four items:I.Breeding high yield and improved quality Northeast Soybeans,directed by Hcilongjiang Academy of Agricultural Sciencee .II.Development of new soybean gerplasms highly resistant to diseases epidemic in Northeast China directed by Northeast Agricultural University.Ⅲ.Exploitation of the potential of wild and semicultivated soybeans for broadening and improving the genetic basis of Northeast soybeans,directed by Jilin Academy of Agricultural Science.Ⅳ.Improving methods and technique for development of new soybean genetic resources.directed by Nanjing Agricultural University .Each item contained several research subjects conducted by research workers of different institutes of agricultural sicences.During the period 1991-1992.considerable promising new germplasms had been discovered or developed.The new germplasms not only possessed specific improved characters but also behaved with appropriate ecological types adapted to different conditions of Northeast.Among the numerous new germplasms developed.Gong Jio 8757-3 had a protein content of 49.41%,100 seed weight 16-17g,and acceptable agronomic characters,which was considered a very valuable new high protein content germplasm.Such developed new germplasma with enforced and imprved genetic basis will be used primarily as parents in soybean cross breeding.

  2. Photopigment basis for dichromatic color vision in the horse.

    Science.gov (United States)

    Carroll, J; Murphy, C J; Neitz, M; Hoeve, J N; Neitz, J

    2001-01-01

    Horses, like other ungulates, are active in the day, at dusk, dawn, and night; and, they have eyes designed to have both high sensitivity for vision in dim light and good visual acuity under higher light levels (Walls, 1942). Typically, daytime activity is associated with the presence of multiple cone classes and color-vision capacity (Jacobs, 1993). Previous studies in other ungulates, such as pigs, goats, cows, sheep and deer, have shown that they have two spectrally different cone types, and hence, at least the photopigment basis for dichromatic color vision (Neitz & Jacobs, 1989; Jacobs, Deegan II, Neitz, Murphy, Miller, & Marchinton, 1994; Jacobs, Deegan II, & Neitz, 1998). Here, electroretinogram flicker photometry was used to measure the spectral sensitivities of the cones in the domestic horse (Equus caballus). Two distinct spectral mechanisms were identified and are consistent with the presence of a short-wavelength-sensitive (S) and a middle-to-long-wavelength-sensitive (M/L) cone. The spectral sensitivity of the S cone was estimated to have a peak of 428 nm, while the M/L cone had a peak of 539 nm. These two cone types would provide the basis for dichromatic color vision consistent with recent results from behavioral testing of horses (Macuda & Timney, 1999; Macuda & Timney, 2000; Timney & Macuda, 2001). The spectral peak of the M/L cone photopigment measured here, in vivo, is similar to that obtained when the gene was sequenced, cloned, and expressed in vitro (Yokoyama & Radlwimmer, 1999). Of the ungulates that have been studied to date, all have the photopigment basis for dichromatic color vision; however, they differ considerably from one another in the spectral tuning of their cone pigments. These differences may represent adaptations to the different visual requirements of different species. PMID:12678603

  3. A Reduced Basis Approach for Some Weakly Stochastic Multiscale Problems

    Institute of Scientific and Technical Information of China (English)

    Claude LE BRIS; Florian THOMINES

    2012-01-01

    In this paper,a multiscale problem arising in material science is considered.The problem involves a random coefficient which is assumed to be a perturbation of a deterministic coefficient,in a sense made precisely in the body of the text.The homogenized limit is then computed by using a perturbation approach.This computation requires repeatedly solving a corrector-like equation for various configurations of the material.For this purpose,the reduced basis approach is employed and adapted to the specific context.The authors perform numerical tests that demonstrate the efficiency of the approach.

  4. The molecular basis of alpha-thalassaemia in Thailand.

    OpenAIRE

    Winichagoon, P.; Higgs, D R; Goodbourn, S E; Clegg, J B; Weatherall, D. J.; Wasi, P

    1984-01-01

    The molecular basis of alpha-thalassaemia has been established in 48 Thai subjects with Hb H disease and 15 with the Hb Bart's hydrops fetalis syndrome. This study has shown that in this population there are at least 18 different types of chromosome carrying seven independent alpha-thalassaemia mutations one of which is a novel deletion removing the entire alpha-globin gene complex. Although there are a limited number of alpha-thalassaemia determinants in the Thai population, there is a remar...

  5. Technical Basis for Electromagnetic Compatibility Regulatory Guidance Update

    Energy Technology Data Exchange (ETDEWEB)

    Ewing, Paul D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Korsah, Kofi [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Harrison, Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wood, Richard Thomas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Mays, Gary T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-03-01

    The objective of this report is to serve as the technical basis document for the next, planned revision of this RG that highlights and provides the rationale for the recommended changes. The structure of this document follows and summarizes the several assessment activities undertaken during the course of this project to evaluate new and updated electromagnetic compatibility (EMC) standards, testing methods and limits, and relevant technology developments being incorporated into plant activities that may have EMI/RFI implications, as well as other specific issues, including impacts of electrostatic discharge (ESD) on safety equipment and impacts on increased usage of wireless devices in nuclear power plants.

  6. The biofield hypothesis: its biophysical basis and role in medicine.

    Science.gov (United States)

    Rubik, Beverly

    2002-12-01

    This paper provides a scientific foundation for the biofield: the complex, extremely weak electromagnetic field of the organism hypothesized to involve electromagnetic bioinformation for regulating homeodynamics. The biofield is a useful construct consistent with bioelectromagnetics and the physics of nonlinear, dynamical, nonequilibrium living systems. It offers a unifying hypothesis to explain the interaction of objects or fields with the organism, and is especially useful toward understanding the scientific basis of energy medicine, including acupuncture, biofield therapies, bioelectromagnetic therapies, and homeopathy. The rapid signal propagation of electromagnetic fields comprising the biofield as well as its holistic properties may account for the rapid, holistic effects of certain alternative and complementary medical interventions.

  7. Structural Basis of Cooperative Ligand Binding by the Glycine Riboswitch

    Energy Technology Data Exchange (ETDEWEB)

    E Butler; J Wang; Y Xiong; S Strobel

    2011-12-31

    The glycine riboswitch regulates gene expression through the cooperative recognition of its amino acid ligand by a tandem pair of aptamers. A 3.6 {angstrom} crystal structure of the tandem riboswitch from the glycine permease operon of Fusobacterium nucleatum reveals the glycine binding sites and an extensive network of interactions, largely mediated by asymmetric A-minor contacts, that serve to communicate ligand binding status between the aptamers. These interactions provide a structural basis for how the glycine riboswitch cooperatively regulates gene expression.

  8. Analysis of Theoretical Basis of Direct Subsidies for Grain Production

    Institute of Scientific and Technical Information of China (English)

    Shengping; SHI; Xiaorong; LUO; Hongjing; LI

    2014-01-01

    Financial distribution to compensate grain production reflects governmental macro-control on grain production and supply. With the reference of agricultural basic theory,agricultural multi-function theory,economic externality theory,public finance and other theories,this article points out that direct subsidies for grain production is reasonable and necessary with six main theoretical basis,namely fundamentality,multi-function,positive externality of grain production,particularity of grain supply and demand,grain safety being closely linked with national security and basic function of service-oriented government.

  9. Molecular basis of complement C3 deficiency in guinea pigs.

    OpenAIRE

    Auerbach, H S; de Burger, R; Dodds, A.; Colten, H R

    1990-01-01

    In experiments to ascertain the biochemical basis of a genetically determined deficiency of the third component of complement (C3) in guinea pigs, we found that C3-deficient liver and peritoneal macrophages contain C3 messenger RNA of normal size (approximately 5 kb) and amounts, that this mRNA programs synthesis of pro-C3 in oocytes primed with liver RNA and in primary macrophage cultures. In each instance, heterodimeric native C3 protein was secreted with normal kinetics but the C3 protein ...

  10. The physical basis of electronics an introductory course

    CERN Document Server

    Harris, D J; Hammond, P

    1975-01-01

    The Physical Basis of Electronics: An Introductory Course, Second Edition is an 11-chapter text that discusses the physical concepts of electronic devices. This edition deals with the considerable advances in electronic techniques, from the introduction of field effect transistors to the development of integrated circuits. The opening chapters discuss the fundamentals of vacuum electronics and solid-state electronics. The subsequent chapters deal with the other components of electronic devices and their functions, including semiconductor diode and transistor as an amplifier and a switch. The d

  11. Using Radial-basis Function Network for CLV

    Institute of Scientific and Technical Information of China (English)

    李纯青; 郑建国

    2002-01-01

    Analysis and comparing with three existing and popularly used forcasting customer lifetime value (CLV) methods, which are the Dwyer method, customer event-method and fitting method, and using performances of the existent artificial neural network, we apply the Radial-basis Function(RBF) network to forecast the CLV, the RBF network can approach the objective function partially. To every input/output pairs, it only needs adjust the weight a little and learn quickly which is very important to the forecast precision. Simulation and experimental results on the customers' data of a company in Shaanxi Province reveal the effectiveness and feasibility of the RBF network.

  12. Snow cover thickness estimation by using radial basis function networks

    Directory of Open Access Journals (Sweden)

    A. Guidali

    2012-07-01

    Full Text Available This work investigates learning and generalisation capabilities of radial basis function networks (RBFN used to solve snow cover thickness estimation model as regression and classification. The model is based on a minimal set of climatic and topographic data collected from a limited number of stations located in the Italian Central Alps. Several experiments have been conceived and conducted adopting different evaluation indexes in both regression and classification tasks. The snow cover thickness estimation by RBFN has been proved a valuable tool able to deal with several critical aspects arising from the specific experimental context.

  13. Nonlinear Time Series Forecast Using Radial Basis Function Neural Networks

    Institute of Scientific and Technical Information of China (English)

    ZHENGXin; CHENTian-Lun

    2003-01-01

    In the research of using Radial Basis Function Neural Network (RBF NN) forecasting nonlinear time series, we investigate how the different clusterings affect the process of learning and forecasting. We find that k-means clustering is very suitable. In order to increase the precision we introduce a nonlinear feedback term to escape from the local minima of energy, then we use the model to forecast the nonlinear time series which are produced by Mackey-Glass equation and stocks. By selecting the k-means clustering and the suitable feedback term, much better forecasting results are obtained.

  14. Nonlinear Time Series Forecast Using Radial Basis Function Neural Networks

    Institute of Scientific and Technical Information of China (English)

    ZHENG Xin; CHEN Tian-Lun

    2003-01-01

    In the research of using Radial Basis Function Neural Network (RBF NN) forecasting nonlinear timeseries, we investigate how the different clusterings affect the process of learning and forecasting. We find that k-meansclustering is very suitable. In order to increase the precision we introduce a nonlinear feedback term to escape from thelocal minima of energy, then we use the model to forecast the nonlinear time series which are produced by Mackey-Glassequation and stocks. By selecting the k-means clustering and the suitable feedback term, much better forecasting resultsare obtained.

  15. Design basis event consequence analyses for the Yucca Mountain project

    International Nuclear Information System (INIS)

    Design basis event (DBE) definition and analysis is an ongoing and integrated activity among the design and analysis groups of the Yucca Mountain Project (YMP). DBE's are those that potentially lead to breach of the waste package and waste form (e.g., spent fuel rods) with consequent release of radionuclides to the environment. A Preliminary Hazards Analysis (PHA) provided a systematic screening of external and internal events that were candidate DBE's that will be subjected to analyses for radiological consequences. As preparation, pilot consequence analyses for the repository subsurface and surface facilities have been performed to define the methodology, data requirements, and applicable regulatory limits

  16. Speculation on a theory of creativity: a physiological basis.

    Science.gov (United States)

    Bachtold, L M

    1980-06-01

    A physiological basis for creative behavior is presented in the hypothesis that creativity is a problem-solving response by intelligent, very active, highly emotional, and extremely introverted persons. Introverts, habitually in a state of high cortical arousal, have low sensory thresholds and stronger than average reactions to sensory stimulation. Highly emotional people have autonomic nervous systems which react quickly and long to stimuli. Subjected to a vast array of disorganized perceptual data and strongly feeling the inconsistencies the active and intelligent individual forms new perceptual relationships to develop feelings of consistency and harmony.

  17. Implementation of Radial Basis Function Neural Network for Image Steganalysis

    Directory of Open Access Journals (Sweden)

    Sambasiva Rao Baragada

    2008-09-01

    Full Text Available Steganographic tools and techniques are becoming more potential and widespread. Illegal use of steganography poses serious challenges to the law enforcement agencies. Limited work has been carried out on supervised steganalysis using neural network as a classifier. We present a combined method of identifying the presence of covert information in a carrier image using fisher’s linear discriminant (FLD function followed by the radial basis function (RBF. Experiments show promising results when compared to the existing supervised steganalysis methods, but arranging the retrieved information is still a challenging problem.

  18. EXPORT BASIS AND FORMATION OF AZERBAIJAN ENERGY POLICY

    Directory of Open Access Journals (Sweden)

    F. I. Iousoubov

    2010-01-01

    Full Text Available The paper analyzes a current situation in national economy and export  of Azerbaijan, budget policy in oil production countries and reveals that nowadays an increase of export potential and diversification of export basis must be one of the main purposes of foreign economy strategy of any state.The paper also shows the necessity to form a State system for encouraging export and national economy in Azerbaijan and prospects of its development and considers an influence of world financial crisis on energy policy of the country.

  19. Solving exponential diophantine equations using lattice basis reduction algorithms

    OpenAIRE

    Weger, de, B.M.M.

    1987-01-01

    Let S be the set of all positive integers with prime divisors from a fixed finite set of primes. Algorithms are given for solving the diophantine inequality 0< x − y < yδ in x, y S for fixed δ (0, 1), and for the diophantine equation x + Y = z in x, y, z S. The method is based on multi-dimensional diophantine approximation, in the real and p-adic case, respectively. The main computational tool is the L3-Basis Reduction Algorithm. Elaborate examples are presented.

  20. Synchronization of chaos using radial basis functions neural networks

    Institute of Scientific and Technical Information of China (English)

    Ren Haipeng; Liu Ding

    2007-01-01

    The Radial Basis Functions Neural Network (RBFNN) is used to establish the model of a response system through the input and output data of the system. The synchronization between a drive system and the response system can be implemented by employing the RBFNN model and state feedback control. In this case, the exact mathematical model, which is the precondition for the conventional method, is unnecessary for implementing synchronization. The effect of the model error is investigated and a corresponding theorem is developed. The effect of the parameter perturbations and the measurement noise is investigated through simulations. The simulation results under different conditions show the effectiveness of the method.

  1. Interim safety basis for fuel supply shutdown facility

    International Nuclear Information System (INIS)

    This ISB in conjunction with the new TSRs, will provide the required basis for interim operation or restrictions on interim operations and administrative controls for the Facility until a SAR is prepared in accordance with the new requirements. It is concluded that the risk associated with the current operational mode of the Facility, uranium closure, clean up, and transition activities required for permanent closure, are within Risk Acceptance Guidelines. The Facility is classified as a Moderate Hazard Facility because of the potential for an unmitigated fire associated with the uranium storage buildings

  2. Molecular basis for the CAT-2 null phenotype in maize

    International Nuclear Information System (INIS)

    Previous reports have described several maize lines whose developmental patterns of catalase gene expression vary from the typical maize line, W64A. Among these variants are the lines A16 and A338, both found to be null for the CAT-2 protein. Identification of a third CAT-2 null line, designated A340, is described. RNA blots and S1 nuclease protection analysis, using [32P]-labeled dCTP, indicate that all three CAT-2 null lines produce a similarly shortened Cat2 transcript. The molecular basis for this aberrant Cat2 transcript is discussed

  3. Molecular Basis and Current Treatment for Alcoholic Liver Disease

    Directory of Open Access Journals (Sweden)

    Juan Armendariz-Borunda

    2010-04-01

    Full Text Available Alcohol use disorders and alcohol dependency affect millions of individuals worldwide. The impact of these facts lies in the elevated social and economic costs. Alcoholic liver disease is caused by acute and chronic exposure to ethanol which promotes oxidative stress and inflammatory response. Chronic consumption of ethanol implies liver steatosis, which is the first morphological change in the liver, followed by liver fibrosis and cirrhosis. This review comprises a broad approach of alcohol use disorders, and a more specific assessment of the pathophysiologic molecular basis, and genetics, as well as clinical presentation and current modalities of treatment for alcoholic liver disease.

  4. Capacitors on the basis of intercalate GaSe

    Directory of Open Access Journals (Sweden)

    Kovalyuk Z. D.

    2010-06-01

    Full Text Available The compound GaSe is obtained by the technique of intercalation of a GaSe single crystal in a melt of the ferroelectric salt KNO3. The x-ray analysis of its crystal structure has been carried out and dielectric frequency characteristics of samples has been measured. It is estab-lished, that accumulation of electric charges occurs in the examined examples in frequency area 100—1000 Hz. A sample of filter capacitor has been created on the basis of the re-ceived compounds.

  5. F[x]-lattice basis reduction algorithm and multisequence synthesis

    Institute of Scientific and Technical Information of China (English)

    王丽萍; 祝跃飞

    2001-01-01

    By means of F[x]-lattice basis reduction algorithm, a new algorithm is presented for synthesizing minimum length linear feedback shift registers (or minimal polynomials) for the given multiple sequences over a field F. Its computational complexity is O( N 2) operations in F where N is the length of each sequence. A necessary and sufficient condition for the uniqueness of minimal polynomials is given. The set and exact number of all minimal polynomials are also described when F is a finite field.

  6. The Theoretical Basis of Task Based Language Teaching

    Institute of Scientific and Technical Information of China (English)

    田雯

    2015-01-01

    The emergence of TBLT(Task Based Language Teaching) is not incidental since PPP(Presentation-PracticeProduction) cannot sufficiently prepare language learners for attaining communication abilities.TBLT,centering on tasks,takes different route to achieve communicative outcome,which is an extension of CLT(Communicative Language Teaching),whose goal is the realization of communicative competence.Hence,to discuss definitions of a task and TBLT will be presented.This paper will further aim to explain the theoretical basis of TBLT highlighting its relationship with CLT.

  7. The Theoretical Basis of Task Based Language Teaching

    Institute of Scientific and Technical Information of China (English)

    田雯

    2015-01-01

    The emergence of TBLT(Task Based Language Teaching) is not incidental since PPP (Presentation-Practice-Production) cannot sufficiently prepare language learners for attaining communication abilities.TBLT,centering on tasks,takes different route to achieve communicative outcome,which is an extension of CLT (Communicative Language Teaching),whose goal is the realization of communicativecompetence.Hence,to discuss definitions of a task and TBLT will be presented.This paper will further aim to explain the theoretical basis of TBLT highlighting its relationship with CLT.

  8. The biofield hypothesis: its biophysical basis and role in medicine.

    Science.gov (United States)

    Rubik, Beverly

    2002-12-01

    This paper provides a scientific foundation for the biofield: the complex, extremely weak electromagnetic field of the organism hypothesized to involve electromagnetic bioinformation for regulating homeodynamics. The biofield is a useful construct consistent with bioelectromagnetics and the physics of nonlinear, dynamical, nonequilibrium living systems. It offers a unifying hypothesis to explain the interaction of objects or fields with the organism, and is especially useful toward understanding the scientific basis of energy medicine, including acupuncture, biofield therapies, bioelectromagnetic therapies, and homeopathy. The rapid signal propagation of electromagnetic fields comprising the biofield as well as its holistic properties may account for the rapid, holistic effects of certain alternative and complementary medical interventions. PMID:12614524

  9. Effective field theory in the harmonic-oscillator basis

    CERN Document Server

    Binder, S; Hagen, G; Papenbrock, T; Wendt, K A

    2015-01-01

    We develop interactions from chiral effective field theory (EFT) that are tailored to the harmonic oscillator basis. As a consequence, ultraviolet convergence with respect to the model space is implemented by construction and infrared convergence can be achieved by enlarging the model space for the kinetic energy. We derive useful analytical expressions for an exact and efficient calculation of matrix elements. By fitting to realistic phase shifts and deuteron data we construct an effective interaction from chiral EFT at next-to-leading order. Many-body coupled-cluster calculations of nuclei up to 132Sn exhibit a fast convergence of ground-state energies and radii in feasible model spaces.

  10. Design of Robots Monitoring System on the Basis of Kingview

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>This paper introduces Robots Monitoring System on the Basis of Kingview.By using the device driver, Kingview acquires real-time data from on-site hardware device,whose results will be shown on the host computer’s screen in the way of animation.Meanwhile,according to configuration requirements and order of operators, Kingview will make Robots run by designed action and produce forms of the on-site data.This system is good at automatically controlling and managing of Robots.

  11. MANAGER PRINCIPLES AS BASIS OF MANAGEMENT STYLE TRANSFORMATION

    Directory of Open Access Journals (Sweden)

    R. A. Kopytov

    2011-01-01

    Full Text Available The paper considers an approach which is based on non-conventional mechanisms of management style formation. The preset level of sustainable management is maintained by self-organized environment created in the process of management style transformation in efficient management principles. Their efficiency is checked within an adaptive algorithm. The algorithm is developed on the basis of combination of evaluative tools  and base of operational  proves. The operating algorithm capability is tested within the framework of an operating enterprise. The obtained results testify about  formation of sustainable business.

  12. Electronic Structure Basis for the Extraordinary Magnetoresistance in WTe2

    Science.gov (United States)

    Pletikosić, I.; Ali, Mazhar N.; Fedorov, A. V.; Cava, R. J.; Valla, T.

    2014-11-01

    The electronic structure basis of the extremely large magnetoresistance in layered nonmagnetic tungsten ditelluride has been investigated by angle-resolved photoelectron spectroscopy. Hole and electron pockets of approximately the same size were found at low temperatures, suggesting that carrier compensation should be considered the primary source of the effect. The material exhibits a highly anisotropic Fermi surface from which the pronounced anisotropy of the magnetoresistance follows. A change in the Fermi surface with temperature was found and a high-density-of-states band that may take over conduction at higher temperatures and cause the observed turn-on behavior of the magnetoresistance in WTe2 was identified.

  13. Toward a scientifically rigorous basis for developing mapped ecological regions.

    Science.gov (United States)

    McMahon, G.; Wiken, E.B.; Gauthier, D.A.

    2004-01-01

    Despite the wide use of ecological regions in conservation and resource-management evaluations and assessments, a commonly accepted theoretical basis for ecological regionalization does not exist. This fact, along with the paucity of focus on ecological regionalization by professional associations, journals, and faculties, has inhibited the advancement of a broadly acceptable scientific basis for the development, use, and verification of ecological regions. The central contention of this article is that ecological regions should improve our understanding of geographic and ecological phenomena associated with biotic and abiotic processes occurring in individual regions and also of processes characteristic of interactions and dependencies among multiple regions. Research associated with any ecoregional framework should facilitate development of hypotheses about ecological phenomena and dominant landscape elements associated with these phenomena, how these phenomena are structured in space, and how they function in a hierarchy. Success in addressing the research recommendations outlined in this article cannot occur within an ad hoc, largely uncoordinated research environment. Successful implementation of this plan will require activities--coordination, funding, and education--that are both scientific and administrative in nature. Perhaps the most important element of an infrastructure to support the scientific work of ecoregionalization would be a national or international authority similar to the Water and Science Technology Board of the National Academy of Sciences.

  14. Hereditary cancer predisposition in children: genetic basis and clinical implications.

    Science.gov (United States)

    Strahm, Brigitte; Malkin, David

    2006-11-01

    Although cancer predisposition syndromes are rare and malignancies arising in this context account for only 1-10% of childhood tumors, studies performed in affected patients and their families have been of unique value for the understanding of cancer development. Three classes of genes (tumor suppressor genes, oncogenes and stability genes) have been identified and shown to be involved in the pathogenesis of familial, as well as sporadic tumors. Cancer has long been recognized as a genetic disease of somatic cells. Despite improved understanding of the molecular basis of predisposition to cancer and better diagnostic tools, the care of these patients and their families remains a major challenge for the clinician. Medical, psychological, ethical and legal issues have to be considered. This review focuses on examples of each class of inherited cancer predisposition syndromes with special implications for patients in the pediatric age group, including retinoblastoma predisposition, Li-Fraumeni syndrome, multiple endocrine neoplasia disorders and Fanconi anemia. The genetic basis of cancer predisposition is discussed as well as the major concepts and controversies in the clinical management of these patients and their families. PMID:16642469

  15. Silicon carbide as a basis for spaceflight optical systems

    Science.gov (United States)

    Curcio, Michael E.

    1994-09-01

    New advances in the areas of microelectronics and micro-mechanical devices have created a momentum in the development of lightweight, miniaturized, electro-optical space subsystems. The performance improvements achieved and new observational techniques developed as a result, have provided a basis for a new range of Small Explorer, Discovery-class and other low-cost mission concepts for space exploration. However, the ultimate objective of low-mass, inexpensive space science missions will only be achieved with a companion development in the areas of flight optical systems and sensor instrument benches. Silicon carbide (SiC) is currently emerging as an attractive technology to fill this need. As a material basis for reflective, flight telescopes and optical benches, SiC offers: the lightweight and stiffness characteristics of beryllium; glass-like inherent stability consistent with performance to levels of diffraction-limited visible resolution; superior thermal properties down to cryogenic temperatures; and an existing, commercially-based material and processing infrastructure like aluminum. This paper will describe the current status and results of on-going technology developments to utilize these material properties in the creation of lightweight, high- performing, thermally robust, flight optical assemblies. System concepts to be discussed range from an 18 cm aperture, 4-mirror, off-axis system weighing less than 2 kg to a 0.5 m, 15 kg reimager. In addition, results in the development of a thermally-stable, `GOES-like' scan mirror will be presented.

  16. Dynamics of learning near singularities in radial basis function networks.

    Science.gov (United States)

    Wei, Haikun; Amari, Shun-Ichi

    2008-09-01

    The radial basis function (RBF) networks are one of the most widely used models for function approximation in the regression problem. In the learning paradigm, the best approximation is recursively or iteratively searched for based on observed data (teacher signals). One encounters difficulties in such a process when two component basis functions become identical, or when the magnitude of one component becomes null. In this case, the number of the components reduces by one, and then the reduced component recovers as the learning process proceeds further, provided such a component is necessary for the best approximation. Strange behaviors, especially the plateau phenomena, have been observed in dynamics of learning when such reduction occurs. There exist singularities in the space of parameters, and the above reduction takes place at the singular regions. This paper focuses on a detailed analysis of the dynamical behaviors of learning near the overlap and elimination singularities in RBF networks, based on the averaged learning equation that is applicable to both on-line and batch mode learning. We analyze the stability on the overlap singularity by solving the eigenvalues of the Hessian explicitly. Based on the stability analysis, we plot the analytical dynamic vector fields near the singularity, which are then compared to those real trajectories obtained by a numeric method. We also confirm the existence of the plateaus in both batch and on-line learning by simulation.

  17. Modeling Marine Electromagnetic Survey with Radial Basis Function Networks

    Directory of Open Access Journals (Sweden)

    Agus Arif

    2011-08-01

    Full Text Available A marine electromagnetic survey is an engineering endeavour to discover the location and dimension of a hydrocarbon layer under an ocean floor. In this kind of survey, an array of electric and magnetic receivers are located on the sea floor and record the scattered, refracted and reflected electromagnetic wave, which has been transmitted by an electric dipole antenna towed by a vessel. The data recorded in receivers must be processed and further analysed to estimate the hydrocarbon location and dimension. To conduct those analyses successfuly, a radial basis function (RBF network could be employed to become a forward model of the input-output relationship of the data from a marine electromagnetic survey. This type of neural networks is working based on distances between its inputs and predetermined centres of some basis functions. A previous research had been conducted to model the same marine electromagnetic survey using another type of neural networks, which is a multi layer perceptron (MLP network. By comparing their validation and training performances (mean-squared errors and correlation coefficients, it is concluded that, in this case, the MLP network is comparatively better than the RBF network

  18. Toward a Scientifically Rigorous Basis for Developing Mapped Ecological Regions

    Science.gov (United States)

    McMahon, Gerard; Wiken, Ed B.; Gauthier, David A.

    2004-04-01

    Despite the wide use of ecological regions in conservation and resource-management evaluations and assessments, a commonly accepted theoretical basis for ecological regionalization does not exist. This fact, along with the paucity of focus on ecological regionalization by professional associations, journals, and faculties, has inhibited the advancement of a broadly acceptable scientific basis for the development, use, and verification of ecological regions. The central contention of this article is that ecological regions should improve our understanding of geographic and ecological phenomena associated with biotic and abiotic processes occurring in individual regions and also of processes characteristic of interactions and dependencies among multiple regions. Research associated with any ecoregional framework should facilitate development of hypotheses about ecological phenomena and dominant landscape elements associated with these phenomena, how these phenomena are structured in space, and how they function in a hierarchy. Success in addressing the research recommendations outlined in this article cannot occur within an ad hoc, largely uncoordinated research environment. Successful implementation of this plan will require activities—coordination, funding, and education—that are both scientific and administrative in nature. Perhaps the most important element of an infrastructure to support the scientific work of ecoregionalization would be a national or international authority similar to the Water and Science Technology Board of the National Academy of Sciences.

  19. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2005-02-25

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. Rev. 0 marks the first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database.

  20. Algebraic evaluation of matrix elements in the Laguerre function basis

    Science.gov (United States)

    McCoy, A. E.; Caprio, M. A.

    2016-02-01

    The Laguerre functions constitute one of the fundamental basis sets for calculations in atomic and molecular electron-structure theory, with applications in hadronic and nuclear theory as well. While similar in form to the Coulomb bound-state eigenfunctions (from the Schrödinger eigenproblem) or the Coulomb-Sturmian functions (from a related Sturm-Liouville problem), the Laguerre functions, unlike these former functions, constitute a complete, discrete, orthonormal set for square-integrable functions in three dimensions. We construct the SU(1, 1) × SO(3) dynamical algebra for the Laguerre functions and apply the ideas of factorization (or supersymmetric quantum mechanics) to derive shift operators for these functions. We use the resulting algebraic framework to derive analytic expressions for matrix elements of several basic radial operators (involving powers of the radial coordinate and radial derivative) in the Laguerre function basis. We illustrate how matrix elements for more general spherical tensor operators in three dimensional space, such as the gradient, may then be constructed from these radial matrix elements.

  1. Prohibition as ontological basis of the Russian legal reality

    Directory of Open Access Journals (Sweden)

    Andrey V. Skorobogatov

    2016-09-01

    Full Text Available Objective to identify characteristics of the nature content and functioning of prohibition in the legal reality of Russia. nbsp Methods the methodological basis of research is the dialectical approach to cognition of social phenomena allowing to analyze them in historical development and functioning in the context of the totality of objective and subjective factors as well as a postmodern paradigm giving the opportunity to explore the legal reality at different levels. Dialectical approach and postmodern paradigm determined the choice of specific research methods comparative hermeneutic discursive. Results the paper proposes a definition of prohibition as a state socio volitional constraining limiting means that under the threat of legal liability is intended to prevent the wrongful act of the subject physical or legal entity and ensure the maintenance of law and order. Prohibition is a necessary means of ensuring the discipline of public relations and the consolidation of legal values designed to assure the effectiveness of legal regulation. Scientific novelty for the first time the article shows that prohibition as a legal category is the ontological basis of legal reality and acts as a determining factor in the content and focus not only of lawmaking and law enforcement but legal behavior as well. Practical significance the main provisions and conclusions of the article can be used in research and teaching when considering questions about the nature content and functioning of prohibitions.

  2. An efficient basis set representation for calculating electrons in molecules

    CERN Document Server

    Jones, Jeremiah R; Lawler, Keith V; Vecharynski, Eugene; Ibrahim, Khaled Z; Williams, Samuel; Abeln, Brant; Yang, Chao; Haxton, Daniel J; McCurdy, C William; Li, Xiaoye S; Rescigno, Thomas N

    2015-01-01

    The method of McCurdy, Baertschy, and Rescigno, J. Phys. B, 37, R137 (2004) is generalized to obtain a straightforward, surprisingly accurate, and scalable numerical representation for calculating the electronic wave functions of molecules. It uses a basis set of product sinc functions arrayed on a Cartesian grid, and yields 1 kcal/mol precision for valence transition energies with a grid resolution of approximately 0.1 bohr. The Coulomb matrix elements are replaced with matrix elements obtained from the kinetic energy operator. A resolution-of-the-identity approximation renders the primitive one- and two-electron matrix elements diagonal; in other words, the Coulomb operator is local with respect to the grid indices. The calculation of contracted two-electron matrix elements among orbitals requires only O(N log(N)) multiplication operations, not O(N^4), where N is the number of basis functions; N = n^3 on cubic grids. The representation not only is numerically expedient, but also produces energies and proper...

  3. Coupled-cluster based basis sets for valence correlation calculations

    Science.gov (United States)

    Claudino, Daniel; Gargano, Ricardo; Bartlett, Rodney J.

    2016-03-01

    Novel basis sets are generated that target the description of valence correlation in atoms H through Ar. The new contraction coefficients are obtained according to the Atomic Natural Orbital (ANO) procedure from CCSD(T) (coupled-cluster singles and doubles with perturbative triples correction) density matrices starting from the primitive functions of Dunning et al. [J. Chem. Phys. 90, 1007 (1989); ibid. 98, 1358 (1993); ibid. 100, 2975 (1993)] (correlation consistent polarized valence X-tuple zeta, cc-pVXZ). The exponents of the primitive Gaussian functions are subject to uniform scaling in order to ensure satisfaction of the virial theorem for the corresponding atoms. These new sets, named ANO-VT-XZ (Atomic Natural Orbital Virial Theorem X-tuple Zeta), have the same number of contracted functions as their cc-pVXZ counterparts in each subshell. The performance of these basis sets is assessed by the evaluation of the contraction errors in four distinct computations: correlation energies in atoms, probing the density in different regions of space via (-3 ≤ n ≤ 3) in atoms, correlation energies in diatomic molecules, and the quality of fitting potential energy curves as measured by spectroscopic constants. All energy calculations with ANO-VT-QZ have contraction errors within "chemical accuracy" of 1 kcal/mol, which is not true for cc-pVQZ, suggesting some improvement compared to the correlation consistent series of Dunning and co-workers.

  4. Mitisiteit as basis vir vergelykende literatuurstudie, met verwysing na waterslangsimboliek

    Directory of Open Access Journals (Sweden)

    J. Lombard

    2004-07-01

    Full Text Available Mythicity as basis for comparative literature, with reference to water snake symbolism Mythicity can be defined as the deliberate intention of probing the numinous dimensions of human existence by means of literature, i.e. mainly narrative forms. In this article the water snake is chosen as prominent archetypal symbol in order to investigate the functioning of mythicity. The water snake is an important symbol in the Southern African context, with its origins in Khoesan ritual and mythology. Recently several stories about water snakes and related mythological creatures have been published in Afrikaans novels and short stories. The water snake has also assimilated influences, inter alia from European, Asian and other African cultures. In this article the potential of mythicity is specifically investigated insofar as it can be utilised as basis for comparative literature. For this purpose the numinous dimensions of a mythic story are treated as equally important as the narrative dimensions. This dialectical balance is therefore used as the main criterion for the comparison of mythic texts. Other related aspects are discussed, namely the importance of the historical context, Jung’s theory of archetypes and the unconscious, and the role of interpretational devices such as metaphor, metonymy, symbolism and allegory. If the balance between numinosity and narrativity is not maintained, the mythic potential of a text is usually reduced. When writers succeed in utilising mythicity as an “open”, dynamic interpretational process, mythic relevance can still be guaranteed within a present-day, postmodern context.

  5. Basis, evidences and consequences of the inherent stellar encocooning

    CERN Document Server

    Celis, L

    2002-01-01

    Based on 7093 observations with photoelectrical photometrical measurements of 191 Mira stars, the following equations (from the papers [1] to [18]) give the basis to establish the Inherent Stellar Encocooning with the spectro-photometric characteristics of the red giant variable stars, especially the Miras, which have large amplitudes (approx 50% of giant variables). The specific basis that justifies a progressive covering with ionized molecules, cold gases, dust and grains are: The relation of the visual amplitudes A sub v =A sub r +E sub A whose real luminosity separate the intrinsic pulsation and amplitude excess effects due to the presence of molecules [145] and an opaque envelope of cool gases; The relation of the visual absolute magnitudes M sub v =M sub v sub r (P)+M sub a (delta sub T sub i sub O V) which is affected by an inherent absorption and/or occultation, and; The relation that defines the probable absolute luminosity and depends on the period and the (Sa) spectral type at maximum M sub v =-2.2...

  6. Anatomicopathological basis and clinical diagnostic significance of Kerley's A line

    International Nuclear Information System (INIS)

    Objective: To study anatomic and pathological basis of Kerley's A line, and to evaluate the role of Kerley's A line in differential diagnosis of diffuse lung diseases (DLD). Methods: HRCT scans, gross specimen section(50-100 μm thickness) and histologic section(5-8 μm thickness) were performed and analyzed comparatively on 28 dry lung specimens from the patients with coal worker's pneumoconiosis and occupational exposure history to coal dusts. At the same time, HRCT images of 176 patients with DLD were retrospectively reviewed for the detection of Kerley's A line. Results: Kerley's A lines were seen in 17 of 28 lung specimens on coronal HRCT images. The anatomic basis of Kerley's A line represented the continuity of two or more thickened interlobular septa (14 eases) and incomplete fibrotic septa between segments or subsegments (3 cases). Histologically, the linear opacities represented the deposits of coal dust, fibrosis, edema, inflammation, thickened vessel wall within interlobular septa. Kerley's A lines were present in 11 of 176 patients (6.3%) including interstitial pulmonary edema (5 cases), viral pneumonia (2 cases), lymphangitic carcinomatosis (2 cases), sarcoidosis (1 cases) and pulmonary alveolar proteinosis (1 cases). Conclusion: Kerley's A line has a limited usefulness in the differential diagnosis of DLD because it is seen infrequently and not discermable. (authors)

  7. Field-Line Resonances in the Current Basis

    Science.gov (United States)

    Ostaszewski, Katharina; Glassmeier, Karl-Heinz; Nabert, Christian

    2016-04-01

    The MHD theory of the field-line resonance is of great importance for the understanding of ultra low-frequency waves in the magnetosphere. Most theoretical works concerning field-line resonance use the electric field as the basis set. In an ideal MHD plasma the field-aligned component of the electrical field vanishes because of the frozen-in theorem. However, a field-aligned current flows to maintain quasi-neutrality. This field-aligned current can only be carried by the transverse MHD Alfvèn wave and is therefore a characteristic feature of these types of waves. In this study we investigate the field-line resonance phenomenon using a three dimensional current vector space as the basis set. Using the model of the box magnetosphere of Southwood (1974) we derive an equation for the field-aligned current. This equation provides a simpler and more detailed insight into the coupling process between the fast mode and the Alfvèn mode. Furthermore we investigate the effect of the Hall current on the field-aligned current by including the Hall term in Ohm's law. It is shown that in some situations the Hall current can nullify the filed-aligned current and therefore prevent the resonance.

  8. Cold Vacuum Drying facility design basis accident analysis documentation

    Energy Technology Data Exchange (ETDEWEB)

    CROWE, R.D.

    2000-08-08

    This document provides the detailed accident analysis to support HNF-3553, Annex B, Spent Nuclear Fuel Project Final Safety Analysis Report (FSAR), ''Cold Vacuum Drying Facility Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the FSAR. The calculations in this document address the design basis accidents (DBAs) selected for analysis in HNF-3553, ''Spent Nuclear Fuel Project Final Safety Analysis Report'', Annex B, ''Cold Vacuum Drying Facility Final Safety Analysis Report.'' The objective is to determine the quantity of radioactive particulate available for release at any point during processing at the Cold Vacuum Drying Facility (CVDF) and to use that quantity to determine the amount of radioactive material released during the DBAs. The radioactive material released is used to determine dose consequences to receptors at four locations, and the dose consequences are compared with the appropriate evaluation guidelines and release limits to ascertain the need for preventive and mitigative controls.

  9. Minimization of Basis Risk in Parametric Earthquake Cat Bonds

    Science.gov (United States)

    Franco, G.

    2009-12-01

    A catastrophe -cat- bond is an instrument used by insurance and reinsurance companies, by governments or by groups of nations to cede catastrophic risk to the financial markets, which are capable of supplying cover for highly destructive events, surpassing the typical capacity of traditional reinsurance contracts. Parametric cat bonds, a specific type of cat bonds, use trigger mechanisms or indices that depend on physical event parameters published by respected third parties in order to determine whether a part or the entire bond principal is to be paid for a certain event. First generation cat bonds, or cat-in-a-box bonds, display a trigger mechanism that consists of a set of geographic zones in which certain conditions need to be met by an earthquake’s magnitude and depth in order to trigger payment of the bond principal. Second generation cat bonds use an index formulation that typically consists of a sum of products of a set of weights by a polynomial function of the ground motion variables reported by a geographically distributed seismic network. These instruments are especially appealing to developing countries with incipient insurance industries wishing to cede catastrophic losses to the financial markets because the payment trigger mechanism is transparent and does not involve the parties ceding or accepting the risk, significantly reducing moral hazard. In order to be successful in the market, however, parametric cat bonds have typically been required to specify relatively simple trigger conditions. The consequence of such simplifications is the increase of basis risk. This risk represents the possibility that the trigger mechanism fails to accurately capture the actual losses of a catastrophic event, namely that it does not trigger for a highly destructive event or vice versa, that a payment of the bond principal is caused by an event that produced insignificant losses. The first case disfavors the sponsor who was seeking cover for its losses while the

  10. DEVELOPMENT OF COMPOSITION OF INFUSION MEDICATION ON BASIS OF MOXIFLOXACIN

    Directory of Open Access Journals (Sweden)

    Almakaeva L.G.

    2015-05-01

    Full Text Available Application of fluoroquinolones covers by experience of treatment more than 800 million patients, and presently they are one of basic classes in the antimicrobial arsenal of practical medicine. Such achievements became possible after the clear understanding of intercommunication of structure and activity of molecules of this class of antibiotics. This knowledge became the basis for the synthesis of new derivatives with a wide range, powerful activity and improved pharmacokinetic profile for the best clinical outcome. Moxifloxacin is 8-methoxyfluoroquinolon of wide spectrum which interacts mainly with DNA gyrase of gram-negative and with topoisomerase of IV type of gram-positive bacteria. He has the extended activity against gram-positive cocci, however keeps activity against gram-negative bacteria. Moxifloxacin also has good activity against atypical respiratory pathogens (Legionella of pneumophila, Chlamydia of pneumoniae and Mycoplasma of pneumoniae. Another his feature is high anti-anaerobic activity. Therefore development of domestic medication with Moxifloxacin - a fluoroquinolone 4 generations - is actual. Materials and methods Research material was a substance of Moxifloxacin hydrochloride, produced by firm «Sansh Biotech Pvt. Ltd.», India, a dosage form on the basis of Moxifloxacin - solution for infusion. Qqualitative and quantitative control of samples of the drug were conducted on parameters which characterize stability: рН, content of active substance, transparency, colour, related impurities, mechanical inclusions on methods, which are described in SPhU. Results and Discussion Proposed the drug is antibiotic of wide spectrum of action of fluoroquinolone. Moxifloxacin hydrochloride is powder pale yellow with slightly hygroscopic nature. He moderately dissolve in water and methanol, poorly will dissolve in hydrochloric acid and ethanol, and practically will not dissolve in an acetone and toluene. рН 0,2 % solution is in a range

  11. On sets of vectors of a finite vector space in which every subset of basis size is a basis II

    CERN Document Server

    Ball, Simeon

    2012-01-01

    This article contains a proof of the MDS conjecture for $k \\leq 2p-2$. That is, that if $S$ is a set of vectors of ${\\mathbb F}_q^k$ in which every subset of $S$ of size $k$ is a basis, where $q=p^h$, $p$ is prime and $q$ is not and $k \\leq 2p-2$, then $|S| \\leq q+1$. It also contains a short proof of the same fact for $k\\leq p$, for all $q$.

  12. Meta-Data Objects as the Basis for System Evolution

    CERN Document Server

    Estrella, Florida; Tóth, N; Kovács, Z; Le Goff, J M; Clatchey, Richard Mc; Toth, Norbert; Kovacs, Zsolt; Goff, Jean-Marie Le

    2001-01-01

    One of the main factors driving object-oriented software development in the Web- age is the need for systems to evolve as user requirements change. A crucial factor in the creation of adaptable systems dealing with changing requirements is the suitability of the underlying technology in allowing the evolution of the system. A reflective system utilizes an open architecture where implicit system aspects are reified to become explicit first-class (meta-data) objects. These implicit system aspects are often fundamental structures which are inaccessible and immutable, and their reification as meta-data objects can serve as the basis for changes and extensions to the system, making it self- describing. To address the evolvability issue, this paper proposes a reflective architecture based on two orthogonal abstractions - model abstraction and information abstraction. In this architecture the modeling abstractions allow for the separation of the description meta-data from the system aspects they represent so that th...

  13. Dynamics Model Abstraction Scheme Using Radial Basis Functions

    Directory of Open Access Journals (Sweden)

    Silvia Tolu

    2012-01-01

    Full Text Available This paper presents a control model for object manipulation. Properties of objects and environmental conditions influence the motor control and learning. System dynamics depend on an unobserved external context, for example, work load of a robot manipulator. The dynamics of a robot arm change as it manipulates objects with different physical properties, for example, the mass, shape, or mass distribution. We address active sensing strategies to acquire object dynamical models with a radial basis function neural network (RBF. Experiments are done using a real robot’s arm, and trajectory data are gathered during various trials manipulating different objects. Biped robots do not have high force joint servos and the control system hardly compensates all the inertia variation of the adjacent joints and disturbance torque on dynamic gait control. In order to achieve smoother control and lead to more reliable sensorimotor complexes, we evaluate and compare a sparse velocity-driven versus a dense position-driven control scheme.

  14. Product design on the basis of fuzzy quality function deployment

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In the implementation of quality function deployment (QFD), the determination of the target values of engineering characteristics is a complex decision process with multiple variables and multiple objectives that should trade off, and optimize all kinds of conflicts and constraints. A fuzzy linear programming model (FLP) is proposed. On the basis of the inherent fuzziness of QFD system, triangular fuzzy numbers are used to represent all the relationships and correlations, and then, the functional relationships between the customer needs and engineering characteristics and the functional correlations among the engineering characteristics are determined with the information in the house of quality (HoQ) fully used. The fuzzy linear programming (FLP) model aims to find the optimal target values of the engineering characteristics to maximize the customer satisfaction. Finally, the proposed method is illustrated by a numerical example.

  15. Biochemical and physiological basis of medical near-infrared spectroscopy

    Science.gov (United States)

    Joebsis-vander Vliet, Frans F.; Joebsis, Paul

    1999-10-01

    Near infrared spectroscopy (NIRS) can monitor both the redox status of Cytochrome c oxidase located in the mitochondria within the cell and the oxygenation of the blood in the tissue being monitored. Since the enzyme catalyzes more than 90% of oxygen utilization, it is the sink for the oxygen while the hemoglobin in the capillaries is the oxygen source. In order to evaluate the oxidative metabolic status of a tissue the optical data obtained from both molecules are commonly interpreted in the basis of test tube experiments with purified preparations. We are concerned that the validity of this practice may not have been tested sufficiently and raise four basic questions that have not yet been answered. Citing some examples of in vitro versus in vivo differences we conclude that more effort should be expended on the in vivo testing of the range of the signals, their natural variability, and the physiological and pathological meaning of their deviations from norm.

  16. Risk informed decision-making and its ethical basis

    International Nuclear Information System (INIS)

    In decision-making under uncertainty there are two main questions that need to be evaluated: (i) What are the future consequences and associated uncertainties of an action, and (ii) what is a good (or right) decision or action. Philosophically these issues are categorized as epistemic questions (i.e. questions of knowledge) and ethical questions (i.e. questions of moral and norms). This paper discusses the second issue, and evaluates different risk management approaches for establishing good decisions, using different ethical theories as a basis. These theories include the utilitarian ethics of Bentley and Mills, and deontological ethics of Kant, Rawls and Habermas. The risk management approaches include cost-benefit analysis (CBA), minimum safety criterion, the ALARP principle and the precautionary principle

  17. Learning Mixtures of Truncated Basis Functions from Data

    DEFF Research Database (Denmark)

    Langseth, Helge; Nielsen, Thomas Dyhre; Pérez-Bernabé, Inmaculada;

    2014-01-01

    -likelihood), they are significantly faster, and therefore indicate that the MoTBF framework can be used for inference and learning in reasonably sized domains. Furthermore, we show how a particular sub- class of MoTBF potentials (learnable by the proposed methods) can be exploited to significantly reduce complexity during inference.......In this paper we investigate methods for learning hybrid Bayesian networks from data. First we utilize a kernel density estimate of the data in order to translate the data into a mixture of truncated basis functions (MoTBF) representation using a convex optimization technique. When utilizing...... propose an alternative learning method that relies on the cumulative distribution function of the data. Empirical results demonstrate the usefulness of the approaches: Even though the methods produce estimators that are slightly poorer than the state of the art (in terms of log...

  18. The Genetic and Molecular Basis of Plant Resistance to Pathogens

    Institute of Scientific and Technical Information of China (English)

    Yan Zhang; Thomas Lubberstedt; Mingliang Xu

    2013-01-01

    Plant pathogens have evolved numerous strategies to obtain nutritive materials from their host,and plants in turn have evolved the preformed physical and chemical barriers as well as sophisticated two-tiered immune system to combat pathogen attacks.Genetically,plant resistance to pathogens can be divided into qualitative and quantitative disease resistance,conditioned by major gene(s) and multiple genes with minor effects,respectively.Qualitative disease resistance has been mostly detected in plant defense against biotrophic pathogens,whereas quantitative disease resistance is involved in defense response to all plant pathogens,from biotrophs,hemibiotrophs to necrotrophs.Plant resistance is achieved through interception of pathogen-derived effectors and elicitation of defense response.In recent years,great progress has been made related to the molecular basis underlying host-pathogen interactions.In this review,we would like to provide an update on genetic and molecular aspects of plant resistance to pathogens.

  19. PERENCANAAN PEMELIHARAAN MESIN BALLMILL DENGAN BASIS RCM (RELIABILITY CENTERED MAINTENANCE

    Directory of Open Access Journals (Sweden)

    Ahmad Kholid Alghofari

    2006-12-01

    Full Text Available Aktifitas produksi sering mengalami hambatan dikarenakan tidak berfungsinya mesin-mesin produksi yang dalam industri manufaktur merupakan komponen utama. Kegagalan beroperasi mesin mengakibatkan downtime yang ujung-ujungnya menurunkan produktifitas perusahaan. Oleh karenanya diperlukan sebuah sistem perencanaan pemeliharaan agar menghasilkan availability (ketersediaan mesin yang optimal. Perusahaan yang dijadikan proyek penelitian adalah PT. Sici Multi IndoMarmer yang merupakan perusahaan yang bergerak dalam bidang produksi keramik (kloset jongkok, kloset duduk, washtafel, tempat sabun dimana sistem pemeliharaan mesin, khususnya mesin ballmill yang telah dilakukan masih bersifat corrective maintenance. Tujuan dari penelitian ini adalah implementasi RCM (reliability centered maintenance untuk dapat menentukan pemeliharan yang optimal serta dapat memprediksikan langkah untuk mengatasi kerusakan yang mungkin terjadi pada periode berikutnya berdasarkan data-data yang ada. Dari pengolahan data dan analisa diperoleh komponen-komponen yang paling sering mengalami kerusakan pada mesin ballmill , penyebab kegagalan, keputusan seleksi dan rekomendasi yang dianjurkan untuk sistem pemeliharaan dengan basis RCM.

  20. Molecular basis for DNA strand displacement by NHEJ repair polymerases.

    Science.gov (United States)

    Bartlett, Edward J; Brissett, Nigel C; Plocinski, Przemyslaw; Carlberg, Tom; Doherty, Aidan J

    2016-03-18

    The non-homologous end-joining (NHEJ) pathway repairs DNA double-strand breaks (DSBs) in all domains of life. Archaea and bacteria utilize a conserved set of multifunctional proteins in a pathway termed Archaeo-Prokaryotic (AP) NHEJ that facilitates DSB repair. Archaeal NHEJ polymerases (Pol) are capable of strand displacement synthesis, whilst filling DNA gaps or partially annealed DNA ends, which can give rise to unligatable intermediates. However, an associated NHEJ phosphoesterase (PE) resects these products to ensure that efficient ligation occurs. Here, we describe the crystal structures of these archaeal (Methanocella paludicola) NHEJ nuclease and polymerase enzymes, demonstrating their strict structural conservation with their bacterial NHEJ counterparts. Structural analysis, in conjunction with biochemical studies, has uncovered the molecular basis for DNA strand displacement synthesis in AP-NHEJ, revealing the mechanisms that enable Pol and PE to displace annealed bases to facilitate their respective roles in DSB repair. PMID:26405198

  1. The genetic basis of laboratory adaptation in Caulobacter crescentus.

    Science.gov (United States)

    Marks, Melissa E; Castro-Rojas, Cyd Marie; Teiling, Clotilde; Du, Lei; Kapatral, Vinayak; Walunas, Theresa L; Crosson, Sean

    2010-07-01

    The dimorphic bacterium Caulobacter crescentus has evolved marked phenotypic changes during its 50-year history of culture in the laboratory environment, providing an excellent system for the study of natural selection and phenotypic microevolution in prokaryotes. Combining whole-genome sequencing with classical molecular genetic tools, we have comprehensively mapped a set of polymorphisms underlying multiple derived phenotypes, several of which arose independently in separate strain lineages. The genetic basis of phenotypic differences in growth rate, mucoidy, adhesion, sedimentation, phage susceptibility, and stationary-phase survival between C. crescentus strain CB15 and its derivative NA1000 is determined by coding, regulatory, and insertion/deletion polymorphisms at five chromosomal loci. This study evidences multiple genetic mechanisms of bacterial evolution as driven by selection for growth and survival in a new selective environment and identifies a common polymorphic locus, zwf, between lab-adapted C. crescentus and clinical isolates of Pseudomonas aeruginosa that have adapted to a human host during chronic infection.

  2. Basis set approach in the constrained interpolation profile method

    International Nuclear Information System (INIS)

    We propose a simple polynomial basis-set that is easily extendable to any desired higher-order accuracy. This method is based on the Constrained Interpolation Profile (CIP) method and the profile is chosen so that the subgrid scale solution approaches the real solution by the constraints from the spatial derivative of the original equation. Thus the solution even on the subgrid scale becomes consistent with the master equation. By increasing the order of the polynomial, this solution quickly converges. 3rd and 5th order polynomials are tested on the one-dimensional Schroedinger equation and are proved to give solutions a few orders of magnitude higher in accuracy than conventional methods for lower-lying eigenstates. (author)

  3. CT diagnosis and pathological basis of localized malignant peritoneal mesothelioma

    International Nuclear Information System (INIS)

    Objective: To study the value of CT diagnosis in localized malignant peritoneal mesothelioma. Methods: CT features of 4 cases with localized malignant peritoneal mesothelioma and the pathological basis were analyzed. Results: All 4 cases showed a large localized mass with an average size of 13 cm. 3 of 4 cases were cystic-solid predominantly multi-cystic; another case was solid accompanied by necrosis. Contrast CT demonstrated marked enhancement in the solid portion of tumor in all 4 cases, the highest CT density was 106 HU(average 76 HU). There was no distant metastasis and ascites. Conclusion: Multi-cysts, remarkable enhancement of the solid area and no distant metastasis may be the main characteristic CT features of localized malignant peritoneal mesothelioma

  4. Condensation within small compartments during design basis accidents

    Energy Technology Data Exchange (ETDEWEB)

    Grgic, D.; Cavlina, N. [Faculty of Electrical Engineering and Computing, University of Zagreb, Unska 3, 10000 Zagreb (Croatia); ANTOLOVIc, A. [NPP Krsko, Engineering Department, Vrbina 12, 8270 Krsko (Slovenia)

    2010-07-01

    During design basis events (LOCA, MSLB) in containment exists possibility for additional condensation within compartments and enclosures with different electrical equipment that can result in submergence of its parts and possible malfunction. The condensation within limit switch compartments (valve actuators) and attached electrical conduits during limiting LOCA and MSLB accidents in containment was analyzed using Gothic computer code with the assumptions corresponding to the ones used to generate containment EQ profiles for thermalhydraulic EQ parameters. The outcome of the analysis is volume of the liquid within the compartment and corresponding liquid level before and after additions of bottom openings (T-drains) required to drain condensed liquid. Different compartment sizes were analyzed during different LOCA and MSLB scenarios. After addition of bottom openings maximum possible condensed liquid level can not cause actuator malfunction. (authors)

  5. Climate Change: The Physical Basis and Latest Results

    CERN Document Server

    CERN. Geneva

    2009-01-01

    The 2007 Assessment Report of the Intergovernmental Panel on Climate Change (IPCC) concludes: "Warming in the climate system is unequivocal." Without the contribution of Physics to climate science over many decades, such a statement would not have been possible. Experimental physics enables us to read climate archives such as polar ice cores and so provides the context for the current changes. For example, today the concentration of CO2 in the atmosphere, the second most important greenhouse gas, is 28% higher than any time during the last 800,000 years. Classical fluid mechanics and numerical mathematics are the basis of climate models from which estimates of future climate change are obtained. But major instabilities and surprises in the Earth System are still unknown. These are also to be considered when the climatic consequences of proposals for geo-engineering are estimated. Only Physics will permit us to further improve our understanding in order to provide the foundation for policy decisions facing the...

  6. Snow cover thickness estimation using radial basis function networks

    Directory of Open Access Journals (Sweden)

    E. Binaghi

    2013-05-01

    Full Text Available This paper reports an experimental study designed for the in-depth investigation of how the radial basis function network (RBFN estimates snow cover thickness as a function of climate and topographic parameters. The estimation problem is modeled in terms of both function regression and classification, obtaining continuous and discrete thickness values, respectively. The model is based on a minimal set of climatic and topographic data collected from a limited number of stations located in the Italian Central Alps. Several experiments have been conceived and conducted adopting different evaluation indexes. A comparison analysis was also developed for a quantitative evaluation of the advantages of the RBFN method over to conventional widely used spatial interpolation techniques when dealing with critical situations originated by lack of data and limited n-homogeneously distributed instrumented sites. The RBFN model proved competitive behavior and a valuable tool in critical situations in which conventional techniques suffer from a lack of representative data.

  7. An incremental design of radial basis function networks.

    Science.gov (United States)

    Yu, Hao; Reiner, Philip D; Xie, Tiantian; Bartczak, Tomasz; Wilamowski, Bogdan M

    2014-10-01

    This paper proposes an offline algorithm for incrementally constructing and training radial basis function (RBF) networks. In each iteration of the error correction (ErrCor) algorithm, one RBF unit is added to fit and then eliminate the highest peak (or lowest valley) in the error surface. This process is repeated until a desired error level is reached. Experimental results on real world data sets show that the ErrCor algorithm designs very compact RBF networks compared with the other investigated algorithms. Several benchmark tests such as the duplicate patterns test and the two spiral problem were applied to show the robustness of the ErrCor algorithm. The proposed ErrCor algorithm generates very compact networks. This compactness leads to greatly reduced computation times of trained networks.

  8. Radial basis function networks and complexity regularization in function learning.

    Science.gov (United States)

    Krzyzak, A; Linder, T

    1998-01-01

    In this paper we apply the method of complexity regularization to derive estimation bounds for nonlinear function estimation using a single hidden layer radial basis function network. Our approach differs from previous complexity regularization neural-network function learning schemes in that we operate with random covering numbers and l(1) metric entropy, making it possible to consider much broader families of activation functions, namely functions of bounded variation. Some constraints previously imposed on the network parameters are also eliminated this way. The network is trained by means of complexity regularization involving empirical risk minimization. Bounds on the expected risk in terms of the sample size are obtained for a large class of loss functions. Rates of convergence to the optimal loss are also derived.

  9. Radial basis function networks for fast contingency ranking

    Energy Technology Data Exchange (ETDEWEB)

    Devaraj, D.; Ramar, K. [Indian Inst. of Technology, Madras (India). Dept. of Electrical Engineering; Yegnanarayana, B. [Indian Inst. of Technology, Madras (India). Dept. of Computer Science and Engineering

    2002-06-01

    This paper presents an artificial neural network-based approach for static-security assessment. The proposed approach uses radial basis function (RBF) networks to predict the system severity level following a given list of contingencies. The RBF networks are trained off-line to capture the nonlinear relationship between the pre-contingency line flows and the post-contingency severity index. A method based on mutual information is proposed for selecting the input features of the networks. Mutual information has the advantage of measuring the general relationship between the independent variables and the dependent variables as against the linear relationship measured by the correlation-based methods. The performance of the proposed approach is demonstrated through contingency ranking in IEEE 30-bus test system. (author)

  10. Efficient VLSI Architecture for Training Radial Basis Function Networks

    Directory of Open Access Journals (Sweden)

    Wen-Jyi Hwang

    2013-03-01

    Full Text Available This paper presents a novel VLSI architecture for the training of radial basis function (RBF networks. The architecture contains the circuits for fuzzy C-means (FCM and the recursive Least Mean Square (LMS operations. The FCM circuit is designed for the training of centers in the hidden layer of the RBF network. The recursive LMS circuit is adopted for the training of connecting weights in the output layer. The architecture is implemented by the field programmable gate array (FPGA. It is used as a hardware accelerator in a system on programmable chip (SOPC for real-time training and classification. Experimental results reveal that the proposed RBF architecture is an effective alternative for applications where fast and efficient RBF training is desired.

  11. Radial Basis Function Networks for Conversion of Sound Spectra

    Directory of Open Access Journals (Sweden)

    Carlo Drioli

    2001-03-01

    Full Text Available In many advanced signal processing tasks, such as pitch shifting, voice conversion or sound synthesis, accurate spectral processing is required. Here, the use of Radial Basis Function Networks (RBFN is proposed for the modeling of the spectral changes (or conversions related to the control of important sound parameters, such as pitch or intensity. The identification of such conversion functions is based on a procedure which learns the shape of the conversion from few couples of target spectra from a data set. The generalization properties of RBFNs provides for interpolation with respect to the pitch range. In the construction of the training set, mel-cepstral encoding of the spectrum is used to catch the perceptually most relevant spectral changes. Moreover, a singular value decomposition (SVD approach is used to reduce the dimension of conversion functions. The RBFN conversion functions introduced are characterized by a perceptually-based fast training procedure, desirable interpolation properties and computational efficiency.

  12. Efficient VLSI architecture for training radial basis function networks.

    Science.gov (United States)

    Fan, Zhe-Cheng; Hwang, Wen-Jyi

    2013-03-19

    This paper presents a novel VLSI architecture for the training of radial basis function (RBF) networks. The architecture contains the circuits for fuzzy C-means (FCM) and the recursive Least Mean Square (LMS) operations. The FCM circuit is designed for the training of centers in the hidden layer of the RBF network. The recursive LMS circuit is adopted for the training of connecting weights in the output layer. The architecture is implemented by the field programmable gate array (FPGA). It is used as a hardware accelerator in a system on programmable chip (SOPC) for real-time training and classification. Experimental results reveal that the proposed RBF architecture is an effective alternative for applications where fast and efficient RBF training is desired.

  13. Learning without local minima in radial basis function networks.

    Science.gov (United States)

    Bianchini, M; Frasconi, P; Gori, M

    1995-01-01

    Learning from examples plays a central role in artificial neural networks. The success of many learning schemes is not guaranteed, however, since algorithms like backpropagation may get stuck in local minima, thus providing suboptimal solutions. For feedforward networks, optimal learning can be achieved provided that certain conditions on the network and the learning environment are met. This principle is investigated for the case of networks using radial basis functions (RBF). It is assumed that the patterns of the learning environment are separable by hyperspheres. In that case, we prove that the attached cost function is local minima free with respect to all the weights. This provides us with some theoretical foundations for a massive application of RBF in pattern recognition.

  14. Relativistic Kinetic-Balance Condition for Explicitly Correlated Basis Functions

    CERN Document Server

    Simmen, Benjamin; Reiher, Markus

    2015-01-01

    This paper presents the derivation of a kinetic-balance condition for explicitly correlated basis functions employed in semi-classical relativistic calculations. Such a condition is important to ensure variational stability in algorithms based on the first-quantized Dirac theory of 1/2-fermions. We demonstrate that the kinetic-balance condition can be obtained from the row reduction process commonly applied to solve systems of linear equations. The resulting form of kinetic balance establishes a relation for the $4^N$ components of the spinor of an $N$-fermion system to the non-relativistic limit, which is in accordance with recent developments in the field of exact decoupling in relativistic orbital-based many-electron theory.

  15. Genetic basis of triatomine behavior: lessons from available insect genomes

    Directory of Open Access Journals (Sweden)

    Jose Manuel Latorre-Estivalis

    2013-01-01

    Full Text Available Triatomines have been important model organisms for behavioural research. Diverse reports about triatomine host search, pheromone communication in the sexual, shelter and alarm contexts, daily cycles of activity, refuge choice and behavioural plasticity have been published in the last two decades. In recent times, a variety of molecular genetics techniques has allowed researchers to investigate elaborate and complex questions about the genetic bases of the physiology of insects. This, together with the current characterisation of the genome sequence of Rhodnius prolixus allows the resurgence of this excellent insect physiology model in the omics era. In the present revision, we suggest that studying the molecular basis of behaviour and sensory ecology in triatomines will promote a deeper understanding of fundamental aspects of insect and, particularly, vector biology. This will allow uncovering unknown features of essential insect physiology questions for a hemimetabolous model organism, promoting more robust comparative studies of insect sensory function and cognition.

  16. Narrow Band Imaging: Technology Basis and Research and Development History.

    Science.gov (United States)

    Gono, Kazuhiro

    2015-11-01

    The first launch of narrow band imaging (NBI) was in 2005. Since then, in most countries where gastrointestinal endoscopies are performed, NBI is the most commonly used optical digital method of performing image-enhanced endoscopy. Thanks to the outstanding efforts of many endoscopists, many clinical studies have been performed and clinical evidence has been gathered. In Japan, since 2010, NBI has been reimbursed under the Japanese national health insurance system. This is owing to the establishment of clinical evidence by physicians. However, even though endoscope systems with NBI function have been widely used outside of Japan, dissemination of knowledge on how to use NBI is insufficient. In this review paper, the technology basis of NBI and its research and development history are described. I hope this information will be helpful for updating physicians' knowledge of NBI.

  17. Design Load Basis for onshore turbines - Revision 00

    DEFF Research Database (Denmark)

    Hansen, Morten Hartvig; Thomsen, Kenneth; Natarajan, Anand;

    DTU Wind Energy is not designing and manufacturing wind turbines and do therefore not need a Design Load Basis (DLB) that is accepted by a certification body. However, to assess the load consequences of innovative features and devices added to existing turbine concepts or new turbine concept...... developed in our research, it is useful to have a full DLB that follows the current design standard and is representative of a general DLB used by the industry. It will set a standard for the design load evaluations performed at DTU Wind Energy, which is aligned with the challenges faced by the industry...... and therefore ensures that our research continues to have a strong foundation in this interaction. Furthermore, the use of a full DLB that follows the current standard can improve and increase the feedback from the research at DTU Wind Energy to the international standardization of design load calculations....

  18. Optimized Radial Basis Function Classifier for Multi Modal Biometrics

    Directory of Open Access Journals (Sweden)

    Anand Viswanathan

    2014-07-01

    Full Text Available Biometric systems can be used for the identification or verification of humans based on their physiological or behavioral features. In these systems the biometric characteristics such as fingerprints, palm-print, iris or speech can be recorded and are compared with the samples for the identification or verification. Multimodal biometrics is more accurate and solves spoof attacks than the single modal bio metrics systems. In this study, a multimodal biometric system using fingerprint images and finger-vein patterns is proposed and also an optimized Radial Basis Function (RBF kernel classifier is proposed to identify the authorized users. The extracted features from these modalities are selected by PCA and kernel PCA and combined to classify by RBF classifier. The parameters of RBF classifier is optimized by using BAT algorithm with local search. The performance of the proposed classifier is compared with the KNN classifier, Naïve Bayesian classifier and non-optimized RBF classifier.

  19. Recent advances in radial basis function collocation methods

    CERN Document Server

    Chen, Wen; Chen, C S

    2014-01-01

    This book surveys the latest advances in radial basis function (RBF) meshless collocation methods which emphasis on recent novel kernel RBFs and new numerical schemes for solving partial differential equations. The RBF collocation methods are inherently free of integration and mesh, and avoid tedious mesh generation involved in standard finite element and boundary element methods. This book focuses primarily on the numerical algorithms, engineering applications, and highlights a large class of novel boundary-type RBF meshless collocation methods. These methods have shown a clear edge over the traditional numerical techniques especially for problems involving infinite domain, moving boundary, thin-walled structures, and inverse problems. Due to the rapid development in RBF meshless collocation methods, there is a need to summarize all these new materials so that they are available to scientists, engineers, and graduate students who are interest to apply these newly developed methods for solving real world’s ...

  20. PRELIMINARY DESIGN BASIS EVENT ANALYSIS OF DOE SNF

    International Nuclear Information System (INIS)

    The purpose of this document is to perform a preliminary design basis event (DBE) analysis of the DOE Spent Nuclear Fuel (SNF) waste form. The objective of the analysis is to determine any preclosure safety impacts of the waste form on the Monitored Geologic Repository (MGR). The scope of this analysis is to determine the offsite dose consequences and associated frequencies of selected DBEs for systems handling disposable canisters that bound all surface and subsurface off-normal events, and to compare these results against regulatory limits. The results of this work are preliminary and are intended to be used to establish a set of preliminary MGR and waste form requirements, to identify mitigation or prevention features that may be required to meet regulatory limits, and to provide input to the Site Recommendation (SR) report. This document is prepared in accordance with the associated development plan (Civilian Radioactive Waste Management System Management and Operating Contractor [CRWMS M andO] 1999g)

  1. Physics Basis for a Spherical Torus Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    C.E. Kessel; J. Menard; S.C. Jardin; T.K. Mau; et al

    1999-11-01

    The spherical torus, or low-aspect-ratio tokamak, is considered as the basis for a fusion power plant. A special class of wall-stabilized high-beta high-bootstrap fraction low-aspect-ratio tokamak equilibrium are analyzed with respect to MHD stability, bootstrap current and external current drive, poloidal field system requirements, power and particle exhaust and plasma operating regime. Overall systems optimization leads to a choice of aspect ratio A = 1:6, plasma elongation kappa = 3:4, and triangularity delta = 0:64. The design value for the plasma toroidal beta is 50%, corresponding to beta N = 7:4, which is 10% below the ideal stability limit. The bootstrap fraction of 99% greatly alleviates the current drive requirements, which are met by tangential neutral beam injection. The design is such that 45% of the thermal power is radiated in the plasma by Bremsstrahlung and trace Krypton, with Neon in the scrapeoff layer radiating the remainder.

  2. Best-basis analysis of broadband tremor signals

    Directory of Open Access Journals (Sweden)

    P. Steffen

    1999-06-01

    Full Text Available Active volcanoes usually generate highly non-stationary broadband tremor signals. Short-time shock events with a frequency content of several decades are superimposed on a stationary narrow band continuous tremor. Tremor signals of this type can be observed in the near field of many active volcanoes. In this paper we will demonstrate the analysis of such signals using a specific tremor signal of Mt. Stromboli (Sicily. We used the Best-Basis Algorithm (BBA in order to compute a spectrogram which is adapted to signal properties on highly different scales. It turns out that the BBA can reveal better fitting properties of the tremor in the time-frequency plane compared to standard methods like Short-Time Fourier Transformation (STFT. Moreover, this very effective algorithm can be used for real time monitoring in the time-frequency plane, for data compression or for de-noising of the tremor signals.

  3. Location and foraging as basis for classification of biotic interactions.

    Science.gov (United States)

    Khabibullin, Viner F

    2016-06-01

    Ecologists face an overwhelming diversity of ecological relationships in natural communities. In this paper, I propose to differentiate various types of the interspecific relations on the basis of two factors: relative localization and foraging activity of interacting partners. I advocate recognition of four types of environments: internal, surface, proximate external and distant external. Then I distinguish four types of synoikia-one partner lives in different degree of proximity to another; and four types of synmensalism: one partner forages in different degree of proximity to another. Intersection of localization-based (four subtypes of synoikia) and foraging-based (four subtypes of synmensalism) rows results in 16 types of interactions. This scheme can serve as a framework that manages diverse biotic interactions in a standardized way. I have made the first step to set up nomenclature standards for terms describing interspecific interactions and hope that this will facilitate research and communication. PMID:27160993

  4. [Genetic basis of head and neck cancers and gene therapy].

    Science.gov (United States)

    Özel, Halil Erdem; Özkırış, Mahmut; Gencer, Zeliha Kapusuz; Saydam, Levent

    2013-01-01

    Surgery and combinations of traditional treatments are not successful enough particularly for advanced stage head and neck cancer. The major disadvantages of chemotherapy and radiation therapy are the lack of specificity for the target tissue and toxicity to the patient. As a result, gene therapy may offer a more specific approach. The aim of gene therapy is to present therapeutic genes into cancer cells which selectively eliminate malignant cells with no systemic toxicity to the patient. This article reviews the genetic basis of head and neck cancers and important concepts in cancer gene therapy: (i) inhibition of oncogenes; (ii) tumor suppressor gene replacement; (iii) regulation of immune response against malignant cells; (iv) genetic prodrug activation; and (v) antiangiogenic gene therapy. Currently, gene therapy is not sufficient to replace the traditional treatments of head and neck cancers, however there is no doubt that it will have an important role in the near future.

  5. Structural basis for simvastatin competitive antagonism of complement receptor 3

    DEFF Research Database (Denmark)

    Jensen, Maria Risager; Bajic, Goran; Zhang, Xianwei;

    2016-01-01

    The complement system is an important part of the innate immune response to infection, but may also cause severe complications during inflammation. Small molecule antagonists to complement receptor (CR)3 have been widely sought, but a structural basis for their mode of action is not available. We...... report here on the structure of the human CR3 ligand-binding I domain in complex with simvastatin. Simvastatin targets the metal ion-dependent adhesion site of the open, ligand-binding conformation of the CR3 I domain by direct contact with the chelated Mg2+ ion. Simvastatin antagonizes I domain binding...... to the complement fragments iC3b and C3d, but not to intercellular adhesion molecule-1. By virtue of the I domain's wide distribution in binding kinetics to ligands, it was possible to identify ligand binding kinetics as discriminator for simvastatin antagonism. In static cellular experiments, 15-25 μM simvastatin...

  6. Confidence intervals for sensitivity indices using reduced-basis metamodels

    CERN Document Server

    Janon, Alexandre; Prieur, Clémentine

    2011-01-01

    Global sensitivity analysis is often impracticable for complex and time demanding numerical models, as it requires a large number of runs. The reduced-basis approach provides a way to replace the original model by a much faster to run code. In this paper, we are interested in the information loss induced by the approximation on the estimation of sensitivity indices. We present a method to provide a robust error assessment, hence enabling significant time savings without sacrifice on precision and rigourousness. We illustrate our method with an experiment where computation time is divided by a factor of nearly 6. We also give directions on tuning some of the parameters used in our estimation algorithms.

  7. Draft Geologic Disposal Requirements Basis for STAD Specification

    Energy Technology Data Exchange (ETDEWEB)

    Ilgen, Anastasia G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bryan, Charles R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hardin, Ernest [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-25

    This document provides the basis for requirements in the current version of Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems, (FCRD-NFST-2014-0000579) that are driven by storage and geologic disposal considerations. Performance requirements for the Standardized Transportation, Aging, and Disposal (STAD) canister are given in Section 3.1 of that report. Here, the requirements are reviewed and the rationale for each provided. Note that, while FCRD-NFST-2014-0000579 provides performance specifications for other components of the STAD storage system (e.g. storage overpack, transfer and transportation casks, and others), these have no impact on the canister performance during disposal, and are not discussed here.

  8. Finite-basis-set expansion methods for scattering problems

    Energy Technology Data Exchange (ETDEWEB)

    Ladanyi, K.; Levay, P.; Apagyi, B.

    1988-10-01

    A wide variety of finite-basis-set expansion methods is applied to electron--hydrogen-atom scattering in the static-exchange approximation. All these methods are based on the Lippmann-Schwinger formalism. A careful analysis of the numerical results is presented with the aim of selecting efficient approaches to the solution of realistic electron-atom (and electron-molecule) scattering problems. The results show that the efficiency of the expansion methods may depend sensitively on the characteristics of the interaction terms. Some difficulties of the simple method of moments are pointed out. A particular least-squares method is proposed to avoid the spurious singularities encountered in applications of the Schwinger variational method to singlet scattering processes.

  9. Macro-modelling via radial basis functionen nets

    Directory of Open Access Journals (Sweden)

    C. Wiegand

    2008-05-01

    Full Text Available By the rising complexity and miniaturisation of the device's dimensions, the density of the conductors increases considerably. Referring to this, locally transient interactions between single physical values become apparent. Therefore, for the investigation and optimisation of integrated circuits it is essential to develop suitable models and simulation surroundings which allow for memory and time-efficient calculation of the behaviour. By means of the dynamic reconstruction theory and the radial basis functions nets the so-called black box models are provided. The description of black box models is derived from the input and output behaviour or so-called time series of a dynamic system. Concerning the time series, the black box model adapts its parameters via the extended Kalman filter. This paper provides a modelling approach that enables fast and efficient simulations.

  10. A New Basis of Geoscience: Whole-Earth Decompression Dynamics

    CERN Document Server

    Herndon, J Marvin

    2013-01-01

    Neither plate tectonics nor Earth expansion theory is sufficient to provide a basis for understanding geoscience. Each theory is incomplete and possesses problematic elements, but both have served as stepping stones to a more fundamental and inclusive geoscience theory that I call Whole-Earth Decompression Dynamics (WEDD). WEDD begins with and is the consequence of our planet's early formation as a Jupiter-like gas giant and permits deduction of:(1) Earth's internal composition, structure, and highly-reduced oxidation state; (2) Core formation without whole-planet melting; (3) Powerful new internal energy sources - proto-planetary energy of compression and georeactor nuclear fission energy; (4) Georeactor geomagnetic field generation; (5) Mechanism for heat emplacement at the base of the crust resulting in the crustal geothermal gradient; (6) Decompression driven geodynamics that accounts for the myriad of observations attributed to plate tectonics without requiring physically-impossible mantle convection, an...

  11. FBIH financial market segmentation on the basis of image factors

    Directory of Open Access Journals (Sweden)

    Arnela Bevanda

    2008-12-01

    Full Text Available The aim of the study is to recognize, single out and define market segments useful for future marketing strategies, using certain statistical techniques on the basis of influence of various image factors of financial institutions. The survey included a total of 500 interviewees: 250 bank clients and 250 clients of insurance companies. Starting from the problem area and research goal, the following hypothesis has been formulated: Basic preferences of clients in regard of image factors while selecting financial institutions are different enough to be used as such for differentiating significant market segments of clients. Two segments have been singled out by cluster analysis and named, respectively, traditionalists and visualists. Results of the research confirmed the established hypothesis and pointed to the fact that managers in the financial institutions of the Federation of Bosnia and Herzegovina (FBIH must undertake certain corrective actions, especially when planning and implementing communication strategies, if they wish to maintain their competitiveness in serving both selected segments.

  12. Risk informed decision-making and its ethical basis

    Energy Technology Data Exchange (ETDEWEB)

    Ersdal, Gerhard [University of Stavanger (Norway)], E-mail: gerhard.ersdal@ptil.no; Aven, Terje [University of Stavanger (Norway)

    2008-02-15

    In decision-making under uncertainty there are two main questions that need to be evaluated: (i) What are the future consequences and associated uncertainties of an action, and (ii) what is a good (or right) decision or action. Philosophically these issues are categorized as epistemic questions (i.e. questions of knowledge) and ethical questions (i.e. questions of moral and norms). This paper discusses the second issue, and evaluates different risk management approaches for establishing good decisions, using different ethical theories as a basis. These theories include the utilitarian ethics of Bentley and Mills, and deontological ethics of Kant, Rawls and Habermas. The risk management approaches include cost-benefit analysis (CBA), minimum safety criterion, the ALARP principle and the precautionary principle.

  13. Reduced basis methods for partial differential equations an introduction

    CERN Document Server

    Quarteroni, Alfio; Negri, Federico

    2016-01-01

    This book provides a basic introduction to reduced basis (RB) methods for problems involving the repeated solution of partial differential equations (PDEs) arising from engineering and applied sciences, such as PDEs depending on several parameters and PDE-constrained optimization.  The book presents a general mathematical formulation of RB methods, analyzes their fundamental theoretical properties, discusses the related algorithmic and implementation aspects, and highlights their built-in algebraic and geometric structures.  More specifically, the authors discuss alternative strategies for constructing accurate RB spaces using greedy algorithms and proper orthogonal decomposition techniques, investigate their approximation properties and analyze offline-online decomposition strategies aimed at the reduction of computational complexity. Furthermore, they carry out both a priori and a posteriori error analysis.  The whole mathematical presentation is made more stimulating by the use of representative examp...

  14. The Gaussian Radial Basis Function Method for Plasma Kinetic Theory

    CERN Document Server

    Hirvijoki, Eero; Belli, Emily; Embréus, Ola

    2015-01-01

    A fundamental macroscopic description of a magnetized plasma is the Vlasov equation supplemented by the nonlinear inverse-square force Fokker-Planck collision operator [Rosenbluth et al., Phys. Rev., 107, 1957]. The Vlasov part describes advection in a six-dimensional phase space whereas the collision operator involves friction and diffusion coefficients that are weighted velocity-space integrals of the particle distribution function. The Fokker-Planck collision operator is an integro-differential, bilinear operator, and numerical discretization of the operator is far from trivial. In this letter, we describe a new approach to discretize the entire kinetic system based on an expansion in Gaussian Radial Basis functions (RBFs). This approach is particularly well-suited to treat the collision operator because the friction and diffusion coefficients can be analytically calculated. Although the RBF method is known to be a powerful scheme for the interpolation of scattered multidimensional data, Gaussian RBFs also...

  15. Spices form the basis of food pairing in Indian cuisine

    CERN Document Server

    Jain, Anupam; Bagler, Ganesh

    2015-01-01

    Culinary practices are influenced by climate, culture, history and geography. Molecular composition of recipes in a cuisine reveals patterns in food preferences. Indian cuisine encompasses a number of diverse sub-cuisines separated by geographies, climates and cultures. Its culinary system has a long history of health-centric dietary practices focused on disease prevention and promotion of health. We study food pairing in recipes of Indian cuisine to show that, in contrast to positive food pairing reported in some Western cuisines, Indian cuisine has a strong signature of negative food pairing; more the extent of flavor sharing between any two ingredients, lesser their co-occurrence. This feature is independent of recipe size and is not explained by ingredient category-based recipe constitution alone. Ingredient frequency emerged as the dominant factor specifying the characteristic flavor sharing pattern of the cuisine. Spices, individually and as a category, form the basis of ingredient composition in Indian...

  16. CONCEPT OF VISHA AND ITS PHARMACOLOGICAL BASIS IN AYURVEDA

    Directory of Open Access Journals (Sweden)

    Bhide Bhargav

    2012-04-01

    Full Text Available Visha dravyas (poisonous drugs are used in various Ayurvedic formulations, in spite of their reported side effects due to their quick effectiveness and in relatively smaller dose. Ayurveda describes many visha dravyas of herbomineral or animal origin. A vivid but scattered description of this can be traced in different texts of Ayurveda and particularly Agadatantra. Visha has been described in terms of its utpatti (origin, types, gunas (properties and pharmacological actions, its effects and management. Guna is the basis to understand the various actions of any dravya. Ten gunas attributed to Visha are just opposite to that of oja. Hence, visha dravya produces its effect by its action on oja. Various shodhana (purification procedures for the safe internal use of these poisonous drugs are also mentioned. In the present article, an attempt has been made to understand visha, its history, types and properties in Ayurvedic parlance by presenting them in a single place.

  17. Neutrino spin-flavor oscillations derived from the mass basis

    CERN Document Server

    Fabbricatore, Riccardo; Studenikin, Alexander

    2016-01-01

    We consider neutrino mixing and oscillations in presence of an arbitrary constant magnetic field with nonzero transversal $B_{\\perp}$ and longitudinal $B_{\\parallel}$ components with respect to the direction of neutrino propagation. The electromagnetic interaction of neutrinos is determined by diagonal and transition neutrino magnetic moments that are introduced for the neutrino mass states. Explicit expressions for the effective neutrino diagonal and transition magnetic moments for the flavor basis in terms of these values for the mass states are obtained. The effective evolution Hamiltonian for the flavor neutrino and the corresponding oscillation probability are derived. The role of the longitudinal magnetic field component is examined. In particular, it is shown that: 1) $B_{\\parallel}$ coupled to the corresponding magnetic moments shifts the neutrino energy, and 2) in case of nonvanishing neutrino transition magnetic moments $B_{\\parallel}$ produces an additional mixing between neutrino states, both in t...

  18. [Induced abortions in the Third Reich. Legal basis and provision].

    Science.gov (United States)

    Link, G

    2000-01-01

    This article analyses, after introductory comments on the legal situation in the German Empire and the Weimar Republic, the legal basis for induced abortions during National Socialist rule in Germany. During this period the first legal definition for eugenically and medically indicated abortions was established. At the same time the prohibition of induced abortions outside these criteria was controlled more strictly and violations were punished more severely. This concerned abortions mainly for social reasons. The intention was to legalize abortion for those deemed "less worthy" while, at the same time, to minimise the number of abortions of those considered as "more valuable" to society. The main thrust of this policy was to increase the birth rate of "valuable" citizens. The second part of this paper focuses on eugenic and medical abortions at the University of Freiburg's Maternity Hospital. PMID:11050762

  19. Propagators and Matrix Basis on Noncommutative Minkowski Space

    CERN Document Server

    Fischer, Andre

    2011-01-01

    We describe an analytic continuation of the Euclidean Grosse-Wulkenhaar and LSZ models which defines a one-parameter family of duality covariant noncommutative field theories interpolating between Euclidean and Minkowski space versions of these models, and provides an alternative regularization to the usual Feynman prescription. This regularization allows for a matrix model representation of the field theories in terms of a complex generalization of the usual basis of Landau wavefunctions. The corresponding propagators are calculated and identified with the Feynman propagators of the field theories. The regulated quantum field theories are shown to be UV/IR-duality covariant. We study the asymptotics of the regularized propagators in position and matrix space representations, and confirm that they generically possess a comparably good decay behaviour as in the Euclidean case.

  20. Archaeological data as a basis for repository marker design

    Energy Technology Data Exchange (ETDEWEB)

    Kaplan, M.F.

    1982-10-01

    This report concerns the development of a marking system for a nuclear waste repository which is very likely to survive for 10,000 years. In order to provide a background on the subject, and for the preliminary design presented in this report, a discussion is presented about the issues involved in human interference with the repository system and the communication of information. A separate chapter summarizes six ancient man-made monuments including: materials, effects of associated textual information on our understanding of the monument, and other features of the ancient monument relevant to marking a repository site. The information presented in the two chapters is used to provide the basis and rationale for a preliminary marker system design presented in a final chapter. 86 refs., 22 figs., 1 tab.

  1. [Induced abortions in the Third Reich. Legal basis and provision].

    Science.gov (United States)

    Link, G

    2000-01-01

    This article analyses, after introductory comments on the legal situation in the German Empire and the Weimar Republic, the legal basis for induced abortions during National Socialist rule in Germany. During this period the first legal definition for eugenically and medically indicated abortions was established. At the same time the prohibition of induced abortions outside these criteria was controlled more strictly and violations were punished more severely. This concerned abortions mainly for social reasons. The intention was to legalize abortion for those deemed "less worthy" while, at the same time, to minimise the number of abortions of those considered as "more valuable" to society. The main thrust of this policy was to increase the birth rate of "valuable" citizens. The second part of this paper focuses on eugenic and medical abortions at the University of Freiburg's Maternity Hospital.

  2. Effective field theory in the harmonic oscillator basis

    Science.gov (United States)

    Binder, S.; Ekström, A.; Hagen, G.; Papenbrock, T.; Wendt, K. A.

    2016-04-01

    We develop interactions from chiral effective field theory (EFT) that are tailored to the harmonic oscillator basis. As a consequence, ultraviolet convergence with respect to the model space is implemented by construction and infrared convergence can be achieved by enlarging the model space for the kinetic energy. In oscillator EFT, matrix elements of EFTs formulated for continuous momenta are evaluated at the discrete momenta that stem from the diagonalization of the kinetic energy in the finite oscillator space. By fitting to realistic phase shifts and deuteron data we construct an effective interaction from chiral EFT at next-to-leading order. Many-body coupled-cluster calculations of nuclei up to 132Sn converge fast for the ground-state energies and radii in feasible model spaces.

  3. Reference Data as a Basis for National Spatial Data Infrastructure

    Directory of Open Access Journals (Sweden)

    Tomáš Mildorf

    2012-12-01

    Full Text Available Spatial data are increasingly being used for a range of applications beyond their, traditional uses. Collection of such data and their update constitute a substantial part of the total costs for their maintenance. In order to ensure sustainable development in the area of geographic information systems, efficient data custody and coordination mechanisms for data sharing must be put in place. This paper shows the importance of reference data as a basis for national spatial data infrastructure that serves as a platform for decision making processes in society. There are several European initiatives supporting the wider use of spatial data. An example is the INSPIRE Directive. Its principles and the main world trends in data integration pave the way to successful SDI driven by stakeholders and coordinated by national mapping agencies.

  4. Aqidah as a Basis of Social Tolerance: The Malaysian Experience

    Directory of Open Access Journals (Sweden)

    Ahmad Munawar Ismail

    2012-06-01

    Full Text Available The purpose of Islam is to develop exceptional human beings based on aqidah. Those with faith will have good life and will, in turn, have a positive influence on people around them. In Malaysia, aqidah forms the basis of Islamic education. Its main objective is to produce students who have God-consciousness in all aspects of life. This survey was carried out by way of questionnaire among secondary school students. The interview method was also used with selected students, teachers and officers from the Ministry of Education. The paper will discuss the influence of aqidah on students in three parts. First is the extent of knowledge of aqidah among the students, second is the relationship between the knowledge of aqidah and students’ social life, and finally, the impact of aqidah on students’ behaviour. This paper concludes that aqidah has a great impact upon students’ social activities.

  5. Developing effective tumor vaccines:basis,challenges and perspectives

    Institute of Scientific and Technical Information of China (English)

    XU Qingwen; CHEN Weifeng

    2007-01-01

    A remarkable advance in tumor immunology during the last decade is the elucidation of the antigenic basis of tumor recognition and destruction.A variety of tumor antigens have been identified using several strategies including conventional experiments and newly developed bioinformatics.Among these antigens,cancer/testis antigen (CT antigen) is considered to be the most promising target for immunotherapy by vaccination.Successful immunotherapy of tumors requires understanding of the natural relationship between the immune system and tumor in the status of differentiation,invasion and maturation.Continued progress in development of effective cancer vaccines depends on the identification of appropriate target antigens,the establishment of optimal immunization strategies without harmful autoimmune responses and the ability of manipulating tumor microenvironment to circumvent immune suppression and to augment the anti-tumor immune response.

  6. Investigation of the physiological basis of the BOLD effect

    CERN Document Server

    Pears, J A

    2001-01-01

    The work described in this thesis is that undertaken by the carried out in the Magnetic Resonance Centre, School of Physics and Astronomy at the University of Nottingham, between October 1997 and September 2001. This thesis describes work performed with the aim of yielding further understanding of the physiological basis behind the BOLD effect. Chapter 1 introduces techniques for monitoring brain function and describes the physiology behind the BOLD effect. Chapter 2 then describes NMR, imaging and the hardware used in the experiments performed in this thesis. A method of measuring cerebral blood volume changes during a visual activation paradigm with high temporal resolution is described in Chapter 3, and the timecourse compared to that of the BOLD response. The slow return to baseline of CBV is discussed. Chapter 4 shows a method of simultaneously measuring blood oxygenation measurements and blood volume changes. The results are shown to be in agreement with published data. The controversial phenomenon know...

  7. Structural basis for molecular recognition at serotonin receptors.

    Science.gov (United States)

    Wang, Chong; Jiang, Yi; Ma, Jinming; Wu, Huixian; Wacker, Daniel; Katritch, Vsevolod; Han, Gye Won; Liu, Wei; Huang, Xi-Ping; Vardy, Eyal; McCorvy, John D; Gao, Xiang; Zhou, X Edward; Melcher, Karsten; Zhang, Chenghai; Bai, Fang; Yang, Huaiyu; Yang, Linlin; Jiang, Hualiang; Roth, Bryan L; Cherezov, Vadim; Stevens, Raymond C; Xu, H Eric

    2013-05-01

    Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology through the 5-HT receptor family. We report the crystal structures of the human 5-HT1B G protein-coupled receptor bound to the agonist antimigraine medications ergotamine and dihydroergotamine. The structures reveal similar binding modes for these ligands, which occupy the orthosteric pocket and an extended binding pocket close to the extracellular loops. The orthosteric pocket is formed by residues conserved in the 5-HT receptor family, clarifying the family-wide agonist activity of 5-HT. Compared with the structure of the 5-HT2B receptor, the 5-HT1B receptor displays a 3 angstrom outward shift at the extracellular end of helix V, resulting in a more open extended pocket that explains subtype selectivity. Together with docking and mutagenesis studies, these structures provide a comprehensive structural basis for understanding receptor-ligand interactions and designing subtype-selective serotonergic drugs. PMID:23519210

  8. After-sales service to manufactured goods on technological basis

    Directory of Open Access Journals (Sweden)

    Miriam Borchardt

    2008-07-01

    Full Text Available This theoretical and exploratory paper aims to build a critical analysis on after-sales services, mainly regarded to manufactured goods on technological basis. The purpose of the research is to achieve some better understanding about the essential elements that are to be taken into account in conceiving such a service, after different approaches. After-sales service is a member of the service package and it can influence customer satisfaction. The studied issues can integrate policies to guiding firms in designing after-sales services. They are: definition of the service itself; strategic issues; the facilities and premises; and the operation management. We aim this theoretical research to be a pre-requisite to launch further empirical researches, mainly in the field of inter-organizational relationships. Key-words: service management; after-sales service; service operations; goods associated to services; inter-organizational relationships.

  9. Approaching the basis set limit for DFT calculations using an environment-adapted minimal basis with perturbation theory: Formulation, proof of concept, and a pilot implementation.

    Science.gov (United States)

    Mao, Yuezhi; Horn, Paul R; Mardirossian, Narbe; Head-Gordon, Teresa; Skylaris, Chris-Kriton; Head-Gordon, Martin

    2016-07-28

    Recently developed density functionals have good accuracy for both thermochemistry (TC) and non-covalent interactions (NC) if very large atomic orbital basis sets are used. To approach the basis set limit with potentially lower computational cost, a new self-consistent field (SCF) scheme is presented that employs minimal adaptive basis (MAB) functions. The MAB functions are optimized on each atomic site by minimizing a surrogate function. High accuracy is obtained by applying a perturbative correction (PC) to the MAB calculation, similar to dual basis approaches. Compared to exact SCF results, using this MAB-SCF (PC) approach with the same large target basis set produces set limit can be even better reproduced. With further improvement to its implementation, MAB-SCF (PC) is a promising lower-cost substitute for conventional large-basis calculations as a method to approach the basis set limit of modern density functionals.

  10. SCHEMA CONGRUITY – A BASIS FOR EVALUATING AMBIENT ADVERTISING EFFECTIVENESS

    Directory of Open Access Journals (Sweden)

    Jurca Maria Alina

    2013-07-01

    Full Text Available The purpose of this paper is to develop a theoretical basis for evaluating ambient advertising in relation to the schema. Ambient advertising, a creative form of out-of-home advertising that conveys direct and contextual messages by using and often altering existing elements of the environment in a way that surprises the target audience, appears to be a solution to the increasing clutter from the media. This study draws on the schema congruity theory to offer a better understanding of how consumers are processing information received from advertisements. Schemas are organized structures of knowledge and expectations that consumers develop in order to categorize the incoming information, and that they access every time they are experiencing a new situation. The schema-based approach is important in understanding consumer behavior because consumers are facing an environment filled with similar brands and products promoted by ads that sound and look alike. According to schema congruity theory information perceived as schema congruent offers a confortable feeling of familiarity and generates limited cognitive processing, whereas schema incongruent information generates surprise and triggers extensive cognitive processing in order to help individual make sense of the unusual situation. Taking into consideration the combination of the different levels of expectancy and relevancy there have been identified three congruency situations: extreme congruity, moderate incongruity and extreme incongruity. Existing research shows that moderate incongruent information offers the best results in recall and recognition and also the highest affect levels compared to extreme congruity and extreme incongruity. Based on evidence from literature this study attempts to position ambient advertising in the moderate incongruity category, thus theoretically proving the assumed effectiveness of this promotional tool. Therefore, this paper is a starting point in bringing the

  11. Neuronal spike sorting based on radial basis function neural networks

    Directory of Open Access Journals (Sweden)

    Taghavi Kani M

    2011-02-01

    Full Text Available "nBackground: Studying the behavior of a society of neurons, extracting the communication mechanisms of brain with other tissues, finding treatment for some nervous system diseases and designing neuroprosthetic devices, require an algorithm to sort neuralspikes automatically. However, sorting neural spikes is a challenging task because of the low signal to noise ratio (SNR of the spikes. The main purpose of this study was to design an automatic algorithm for classifying neuronal spikes that are emitted from a specific region of the nervous system."n "nMethods: The spike sorting process usually consists of three stages: detection, feature extraction and sorting. We initially used signal statistics to detect neural spikes. Then, we chose a limited number of typical spikes as features and finally used them to train a radial basis function (RBF neural network to sort the spikes. In most spike sorting devices, these signals are not linearly discriminative. In order to solve this problem, the aforesaid RBF neural network was used."n "nResults: After the learning process, our proposed algorithm classified any arbitrary spike. The obtained results showed that even though the proposed Radial Basis Spike Sorter (RBSS reached to the same error as the previous methods, however, the computational costs were much lower compared to other algorithms. Moreover, the competitive points of the proposed algorithm were its good speed and low computational complexity."n "nConclusion: Regarding the results of this study, the proposed algorithm seems to serve the purpose of procedures that require real-time processing and spike sorting.

  12. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2009-08-28

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document.

  13. Einflüsse von Pimecrolimus und Triamcinolonacetonid auf die epidermale Hautbarriere bei atopischer Dermatitis

    OpenAIRE

    Weppner, Merle

    2016-01-01

    Untersuchung der epidermalen Hautbarriere durch Bestimmung klinischer Parameter, biophysikalischer Parameter (Transepidermaler Wasserverlust, Hauthydratation, Integrität des St. corneum), lichtmikroskopischer Analysen (Immunhistochemie auf epidermale Proliferations- und Differenzierungsmarker) sowie elektronenmikroskopischer Analysen (Lamellenkörperchen/ lamellar bodies).

  14. The Polynomial Form of the Scattering Equations is an H-Basis

    CERN Document Server

    Bosma, Jorrit; Zhang, Yang

    2016-01-01

    We prove that the polynomial form of the scattering equations is a Macaulay H-basis. We demonstrate that this H-basis facilitates integrand reduction and global residue computations in a way very similar to using a Gr\\"obner basis, but circumvents the heavy computation of the latter. As an example, we apply the H-basis to prove the conjecture that the dual basis of the polynomial scattering equations must contain one constant term.

  15. Capital investment as a basis for innovative enterprises’ capacity development

    Directory of Open Access Journals (Sweden)

    V.V. Shekman

    2013-03-01

    Full Text Available The aim of the article. The purpose of the article is to study the matter of investment in fixed capital of Ukraines enterprises as a basis of country innovation development and to determine the role of fixed capital investments in innovative development providing.The results of the analysis. In the article the structure and the volume of foreign investments attracting to the national economy of Ukraine during 2003-2012 are analyzed. It is determined that in spite of annual positive foreign investments volume growth in compare to the previous year the dynamic shows the investment climate deterioration because of the investment runoff. The determined trends show the problem in providing a countrys sunstainable economic development in the innovative aspect. The basis of the countrys innovative development is the investment activation into the enterprises fixed capital. The economic activity of the subjects of economy and the level of their competitiveness in domestic and foreign markets are determined by the essential level of fixed capital funds. They are the basis of the enterprise productive process. According to the analysis Ukrainian enterprises have a high level of fixed capital consumption. The rate of investments aimed to renovate fixed capital is too small. The volumes of fixed capital funds renovation and reproduction financing at the domestic enterprises reduced according to the reduction production volume and joint profits. The main source of fixed capital funds reproduction at the industrial enterprises of Ukraine is the main financial assets of the enterprise. The catastrophic lack of internal and external funds was the reason why heads of enterprises refused to implement new innovative projects and carry out all required actions on calling in accumulated credit obligations to the counteragents.Investment increasing will make it possible to renew enterprises fixed capital funds, to reorganize the coproduction and to balance the

  16. Toward a physical basis of attention and self-regulation

    Science.gov (United States)

    Posner, Michael I.; Rothbart, Mary K.

    2009-06-01

    The concept of self-regulation is central to the understanding of human development. Self-regulation allows effective socialization and predicts both psychological pathologies and levels of achievement in schools. What has been missing are neural mechanisms to provide understanding of the cellular and molecular basis for self-regulation. We show that self-regulation can be measured during childhood by parental reports and by self-reports of adolescents and adults. These reports are summarized by a higher order factor called effortful control, which reflects perceptions about the ability of a given person to regulate their behavior in accord with cultural norms. Throughout childhood effortful control is related to children's performance in computerized conflict related tasks. Conflict tasks have been shown in neuroimaging studies to activate specific brain networks of executive attention. Several brain areas work together at rest and during cognitive tasks to regulate competing brain activity and thus control resulting behavior. The cellular structure of the anterior cingulate and insula contain cells, unique to humans and higher primates that provide strong links to remote brain areas. During conflict tasks, anterior cingulate activity is correlated with activity in remote sensory and emotional systems, depending upon the information selected for the task. During adolescence the structure and activity of the anterior cingulate has been found to be correlated with self-reports of effortful control. Studies have provided a perspective on how genes and environment act to shape the executive attention network, providing a physical basis for self-regulation. The anterior cingulate is regulated by dopamine. Genes that influence dopamine levels in the CNS have been shown to influence the efficiency of self-regulation. For example, alleles of the COMT gene that influence the efficiency of dopamine transmission are related to the ability to resolve conflict. Humans with

  17. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2007-03-12

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. Rev. 0 marks the first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database. Revision numbers that are whole numbers reflect major revisions typically involving changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document. Revision Log: Rev. 0 (2/25/2005) Major revision and expansion. Rev. 0.1 (3/12/2007) Minor

  18. Adaptive radial basis function mesh deformation using data reduction

    Science.gov (United States)

    Gillebaart, T.; Blom, D. S.; van Zuijlen, A. H.; Bijl, H.

    2016-09-01

    Radial Basis Function (RBF) mesh deformation is one of the most robust mesh deformation methods available. Using the greedy (data reduction) method in combination with an explicit boundary correction, results in an efficient method as shown in literature. However, to ensure the method remains robust, two issues are addressed: 1) how to ensure that the set of control points remains an accurate representation of the geometry in time and 2) how to use/automate the explicit boundary correction, while ensuring a high mesh quality. In this paper, we propose an adaptive RBF mesh deformation method, which ensures the set of control points always represents the geometry/displacement up to a certain (user-specified) criteria, by keeping track of the boundary error throughout the simulation and re-selecting when needed. Opposed to the unit displacement and prescribed displacement selection methods, the adaptive method is more robust, user-independent and efficient, for the cases considered. Secondly, the analysis of a single high aspect ratio cell is used to formulate an equation for the correction radius needed, depending on the characteristics of the correction function used, maximum aspect ratio, minimum first cell height and boundary error. Based on the analysis two new radial basis correction functions are derived and proposed. This proposed automated procedure is verified while varying the correction function, Reynolds number (and thus first cell height and aspect ratio) and boundary error. Finally, the parallel efficiency is studied for the two adaptive methods, unit displacement and prescribed displacement for both the CPU as well as the memory formulation with a 2D oscillating and translating airfoil with oscillating flap, a 3D flexible locally deforming tube and deforming wind turbine blade. Generally, the memory formulation requires less work (due to the large amount of work required for evaluating RBF's), but the parallel efficiency reduces due to the limited

  19. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2010-04-01

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

  20. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2011-04-04

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

  1. Analysis of technological process on the basis of efficiency criterion

    Directory of Open Access Journals (Sweden)

    B. Krupińska

    2006-04-01

    Full Text Available Purpose: Technological process is a basic determinant of correctness of industrial company’s functioning on the market. In this connection they should treat with the priority all activities connected with technology, technology management and controlling, that is with their continuous improvement.Design/methodology/approach: The created model made it possible to analyze the chosen technological processes for the sake of efficiency criteria, which describe the relationships: operation – material, operation – machine, operation – man, operation – technological parameters.Findings The in this thesis conducted analysis includes hypothetical technological processes of producing typical machine pieces. Within their scope also the nonmaterial parameters of technological process have been taken into account, which resulted from arts of applied samples and projecting of the technological process. Practical implications: One has worked out an application that allows to analyze the efficiency of technological process in aspect of nonmaterial values and has used neuronal nets to verify particle indicators of quality of a process operation. Indicators appointment makes it possible to evaluate the process efficiency, which can constitute an optimization basis of particular operation.Originality/value: As a result of this analysis gained data enabled to optimize the technological process by estimating influence of the analyzed parameters on the whole of process and optimization conducting of any process.

  2. Structural basis of substrate discrimination and integrin binding by autotaxin

    Energy Technology Data Exchange (ETDEWEB)

    Hausmann, Jens; Kamtekar, Satwik; Christodoulou, Evangelos; Day, Jacqueline E.; Wu, Tao; Fulkerson, Zachary; Albers, Harald M.H.G.; van Meeteren, Laurens A.; Houben, Anna J.S.; van Zeijl, Leonie; Jansen, Silvia; Andries, Maria; Hall, Troii; Pegg, Lyle E.; Benson, Timothy E.; Kasiem, Mobien; Harlos, Karl; Vander Kooi, Craig W.; Smyth, Susan S.; Ovaa, Huib; Bollen, Mathieu; Morris, Andrew J.; Moolenaar, Wouter H.; Perrakis, Anastassis (Pfizer); (Leuven); (Oxford); (NCI-Netherlands); (Kentucky)

    2013-09-25

    Autotaxin (ATX, also known as ectonucleotide pyrophosphatase/phosphodiesterase-2, ENPP2) is a secreted lysophospholipase D that generates the lipid mediator lysophosphatidic acid (LPA), a mitogen and chemoattractant for many cell types. ATX-LPA signaling is involved in various pathologies including tumor progression and inflammation. However, the molecular basis of substrate recognition and catalysis by ATX and the mechanism by which it interacts with target cells are unclear. Here, we present the crystal structure of ATX, alone and in complex with a small-molecule inhibitor. We have identified a hydrophobic lipid-binding pocket and mapped key residues for catalysis and selection between nucleotide and phospholipid substrates. We have shown that ATX interacts with cell-surface integrins through its N-terminal somatomedin B-like domains, using an atypical mechanism. Our results define determinants of substrate discrimination by the ENPP family, suggest how ATX promotes localized LPA signaling and suggest new approaches for targeting ATX with small-molecule therapeutic agents.

  3. Assessment of the basis of mercury tolerance in Dunaliella tertiolecta

    Energy Technology Data Exchange (ETDEWEB)

    Davies, A.G.

    1976-01-01

    The specific growth rate of Dunaliella tertiolecta was unaffected by mercury II concentrations of at least 2.03 ..mu..g at/l. At 10 ..mu..g at/l, it was eventually reduced by 84 percent but growth continued, giving a final level of cell material only 13 percent below that in a mercury-free control. At this concentration, however, growth was largely uncoupled from division and giant cells were produced, probably due to the effect of mercury upon the production of methionine which is known to be implicated in the process of cell division. The basis of the mercury tolerance was investigated in terms of (1) mercury detoxication in the culture medium by complex or compound formation between the metal and metabolites produced by the cells, (2) the concentration of sulfhydryl groups both within the cells as possible sequestration sites and in the cell membrane where any molecular disruption and permeability changes produced by the metal first occur, (3) the absence of cellular potassium leakage and (4) the resistance of the cell membrane to the uptake of mercury II ions. Where possible, the results were compared with those from determinations of the same properties of the mercury-sensitive species Isochrysis galbana. The experiments indicated that the mercury tolerance of D. tertiolecta is partly related to the slower rate of mercury accumulation by this species, but is largely due to the detoxication of the mercury within the cell possibly by the precipitation of a highly insoluble mercury compound.

  4. The Pharmacological Basis of Cannabis Therapy for Epilepsy.

    Science.gov (United States)

    Reddy, Doodipala Samba; Golub, Victoria M

    2016-04-01

    Recently, cannabis has been suggested as a potential alternative therapy for refractory epilepsy, which affects 30% of epilepsy, both adults and children, who do not respond to current medications. There is a large unmet medical need for new antiepileptics that would not interfere with normal function in patients with refractory epilepsy and conditions associated with refractory seizures. The two chief cannabinoids are Δ-9-tetrahyrdrocannabinol, the major psychoactive component of marijuana, and cannabidiol (CBD), the major nonpsychoactive component of marijuana. Claims of clinical efficacy in epilepsy of CBD-predominant cannabis or medical marijuana come mostly from limited studies, surveys, or case reports. However, the mechanisms underlying the antiepileptic efficacy of cannabis remain unclear. This article highlights the pharmacological basis of cannabis therapy, with an emphasis on the endocannabinoid mechanisms underlying the emerging neurotherapeutics of CBD in epilepsy. CBD is anticonvulsant, but it has a low affinity for the cannabinoid receptors CB1 and CB2; therefore the exact mechanism by which it affects seizures remains poorly understood. A rigorous clinical evaluation of pharmaceutical CBD products is needed to establish the safety and efficacy of their use in the treatment of epilepsy. Identification of mechanisms underlying the anticonvulsant efficacy of CBD is also critical for identifying other potential treatment options.

  5. Immune evasion in cancer: Mechanistic basis and therapeutic strategies.

    Science.gov (United States)

    Vinay, Dass S; Ryan, Elizabeth P; Pawelec, Graham; Talib, Wamidh H; Stagg, John; Elkord, Eyad; Lichtor, Terry; Decker, William K; Whelan, Richard L; Kumara, H M C Shantha; Signori, Emanuela; Honoki, Kanya; Georgakilas, Alexandros G; Amin, Amr; Helferich, William G; Boosani, Chandra S; Guha, Gunjan; Ciriolo, Maria Rosa; Chen, Sophie; Mohammed, Sulma I; Azmi, Asfar S; Keith, W Nicol; Bilsland, Alan; Bhakta, Dipita; Halicka, Dorota; Fujii, Hiromasa; Aquilano, Katia; Ashraf, S Salman; Nowsheen, Somaira; Yang, Xujuan; Choi, Beom K; Kwon, Byoung S

    2015-12-01

    Cancer immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Although considerable progress has been made in understanding how cancers evade destructive immunity, measures to counteract tumor escape have not kept pace. There are a number of factors that contribute to tumor persistence despite having a normal host immune system. Immune editing is one of the key aspects why tumors evade surveillance causing the tumors to lie dormant in patients for years through "equilibrium" and "senescence" before re-emerging. In addition, tumors exploit several immunological processes such as targeting the regulatory T cell function or their secretions, antigen presentation, modifying the production of immune suppressive mediators, tolerance and immune deviation. Besides these, tumor heterogeneity and metastasis also play a critical role in tumor growth. A number of potential targets like promoting Th1, NK cell, γδ T cell responses, inhibiting Treg functionality, induction of IL-12, use of drugs including phytochemicals have been designed to counter tumor progression with much success. Some natural agents and phytochemicals merit further study. For example, use of certain key polysaccharide components from mushrooms and plants have shown to possess therapeutic impact on tumor-imposed genetic instability, anti-growth signaling, replicative immortality, dysregulated metabolism etc. In this review, we will discuss the advances made toward understanding the basis of cancer immune evasion and summarize the efficacy of various therapeutic measures and targets that have been developed or are being investigated to enhance tumor rejection. PMID:25818339

  6. Development of engineering technology basis for industrialization of pyrometallurgical reprocessing

    International Nuclear Information System (INIS)

    Development of the engineering technology basis of pyrometallurgical reprocessing is a key issue for industrialization. For development of the transport technologies of molten salt and liquid cadmium at around 500 deg. C, a salt transport test rig and a metal transport test rig were installed in Ar glove box. Function of centrifugal pump and 1/2'' declined tubing were confirmed with LiCl- KCl molten salt. The transport behavior of molten salt was found to follow that of water. Function of centrifugal pump, vacuum sucking and 1/2'' declined tubing were confirmed with liquid Cd. With employing the transport technologies, industrialization applicable electro-refiner was newly designed and engineering-scale model was fabricated in Ar glove box. The electro-refiner has semi-continuous liquid Cd cathode instead of conventional one used in small-scale tests. With using actinide-simulating elements, demonstration of industrial-scale throughput will be carried out in this electro-refiner for more precise evaluation of industrialization potential of pyrometallurgical reprocessing. (authors)

  7. The neural basis of responsibility attribution in decision-making.

    Directory of Open Access Journals (Sweden)

    Peng Li

    Full Text Available Social responsibility links personal behavior with societal expectations and plays a key role in affecting an agent's emotional state following a decision. However, the neural basis of responsibility attribution remains unclear. In two previous event-related brain potential (ERP studies we found that personal responsibility modulated outcome evaluation in gambling tasks. Here we conducted a functional magnetic resonance imaging (fMRI study to identify particular brain regions that mediate responsibility attribution. In a context involving team cooperation, participants completed a task with their teammates and on each trial received feedback about team success and individual success sequentially. We found that brain activity differed between conditions involving team success vs. team failure. Further, different brain regions were associated with reinforcement of behavior by social praise vs. monetary reward. Specifically, right temporoparietal junction (RTPJ was associated with social pride whereas dorsal striatum and dorsal anterior cingulate cortex (ACC were related to reinforcement of behaviors leading to personal gain. The present study provides evidence that the RTPJ is an important region for determining whether self-generated behaviors are deserving of praise in a social context.

  8. Entangled quantum key distribution with a biased basis choice

    Energy Technology Data Exchange (ETDEWEB)

    Erven, Chris; Ma Xiongfeng; Laflamme, Raymond; Weihs, Gregor [Institute for Quantum Computing and Department of Physics and Astronomy, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1 (Canada)], E-mail: cerven@iqc.ca

    2009-04-15

    We investigate a quantum key distribution (QKD) scheme that utilizes a biased basis choice in order to increase the efficiency of the scheme. The optimal bias between the two measurement bases, a more refined error analysis and finite key size effects are all studied in order to assure the security of the final key generated with the system. We then implement the scheme in a local entangled QKD system that uses polarization entangled photon pairs to securely distribute the key. A 50/50 non-polarizing beamsplitter (BS) with different optical attenuators is used to simulate a variable BS in order to allow us to study the operation of the system for different biases. Over 6 h of continuous operation with a total bias of 0.9837/0.0163 (Z/X), we were able to generate 0.4567 secure key bits per raw key bit as compared to 0.2550 secure key bits per raw key bit for the unbiased case. This represents an increase in the efficiency of the key generation rate by 79%.

  9. [Molecular basis of stress-evoked psychiatric disturbances].

    Science.gov (United States)

    Beszczyńska, Beata

    2007-11-20

    Stress, defined as coping with environmental challenges, involves the activation of the neuronal and neurohormonal systems. Central monoaminergic (noradrenergic, dopaminergic, serotonergic) neural networks, limbic structures, the sympathoadrenal system, the hypothalamo-pituitary-adrenal axis, and the immune system are considered the most important stress pathways. Their activation determines stress reactivity and pathological consequences on exposure to situations of distress. Both trauma and long-term stress can cause alterations in the activities of neuroanatomical structures and neural networks within the central nervous system. These neurohormonal changes are associated with post-traumatic stress disorder (PTSD), a disturbance thought to be one of the most serious psychiatric illnesses. PTSD may develop in individuals after exposure to a traumatic event (war, violence, accident) and is manifested by various symptoms, such as re-experiencing, flashbacks, intrusive thoughts, impaired memory of the event, sleep disorders, nightmares, panic attacks, and depression. In this review the neurohormonal changes associated with experiencing stress are presented to highlight the molecular and hormonal basis of PTSD.

  10. New insights into the genetic basis of infertility

    Directory of Open Access Journals (Sweden)

    Venkatesh T

    2014-12-01

    Full Text Available Thejaswini Venkatesh,1 Padmanaban S Suresh,2 Rie Tsutsumi3 1Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences, Bangalore, 2Centre for Biomedical Research, VIT University, Vellore, India; 3University of Tokushima, Institute of Health Bioscience, Department of Public Health and Nutrition, Tokushima, Japan Abstract: Infertility is a disease of the reproductive system characterized by inability to achieve pregnancy after 12 or more months of regular unprotected sexual intercourse. A variety of factors, including ovulation defects, spermatogenic failure, parental age, obesity, and infections have been linked with infertility, in addition to specific karyotypes and genotypes. The study of genes associated with infertility in rodent models has expanded the field of translational genetics in identifying the underlying cause of human infertility problems. Many intriguing aspects of the molecular basis of infertility in humans remain poorly understood; however, application of genetic knowledge in this field looks promising. The growing literature on the genetics of human infertility disorders deserves attention and a critical concise summary is required. This paper provides information obtained from a systematic analysis of the literature related to current research into the genetics of infertility affecting both sexes. Keywords: infertility, genetics, polycystic ovary syndrome, premature ovarian failure, spermatogenic failure, cystic fibrosis

  11. Partially repeatable genetic basis of benthic adaptation in threespine sticklebacks.

    Science.gov (United States)

    Erickson, Priscilla A; Glazer, Andrew M; Killingbeck, Emily E; Agoglia, Rachel M; Baek, Jiyeon; Carsanaro, Sara M; Lee, Anthony M; Cleves, Phillip A; Schluter, Dolph; Miller, Craig T

    2016-04-01

    The extent to which convergent adaptation to similar ecological niches occurs by a predictable genetic basis remains a fundamental question in biology. Threespine stickleback fish have undergone an adaptive radiation in which ancestral oceanic populations repeatedly colonized and adapted to freshwater habitats. In multiple lakes in British Columbia, two different freshwater ecotypes have evolved: a deep-bodied benthic form adapted to forage near the lake substrate, and a narrow-bodied limnetic form adapted to forage in open water. Here, we use genome-wide linkage mapping in marine × benthic F2 genetic crosses to test the extent of shared genomic regions underlying benthic adaptation in three benthic populations. We identify at least 100 Quantitative Trait Loci (QTL) harboring genes influencing skeletal morphology. The majority of QTL (57%) are unique to one cross. However, four genomic regions affecting eight craniofacial and armor phenotypes are found in all three benthic populations. We find that QTL are clustered in the genome and overlapping QTL regions are enriched for genomic signatures of natural selection. These findings suggest that benthic adaptation has occurred via both parallel and nonparallel genetic changes. PMID:26947264

  12. Structural basis of transcobalamin recognition by human CD320 receptor

    Science.gov (United States)

    Alam, Amer; Woo, Jae-Sung; Schmitz, Jennifer; Prinz, Bernadette; Root, Katharina; Chen, Fan; Bloch, Joël S.; Zenobi, Renato; Locher, Kaspar P.

    2016-07-01

    Cellular uptake of vitamin B12 (cobalamin) requires capture of transcobalamin (TC) from the plasma by CD320, a ubiquitous cell surface receptor of the LDLR family. Here we present the crystal structure of human holo-TC in complex with the extracellular domain of CD320, visualizing the structural basis of the TC-CD320 interaction. The observed interaction chemistry can rationalize the high affinity of CD320 for TC and lack of haptocorrin binding. The in vitro affinity and complex stability of TC-CD320 were quantitated using a solid-phase binding assay and thermostability analysis. Stable complexes with TC were also observed for the disease-causing CD320ΔE88 mutant and for the isolated LDLR-A2 domain. We also determined the structure of the TC-CD320ΔE88 complex, which revealed only minor changes compared with the wild-type complex. Finally, we demonstrate significantly reduced in vitro affinity of TC for CD320 at low pH, recapitulating the proposed ligand release during the endocytic pathway.

  13. Neural Basis of Brain Dysfunction Produced by Early Sleep Problems.

    Science.gov (United States)

    Kohyama, Jun

    2016-01-01

    There is a wealth of evidence that disrupted sleep and circadian rhythms, which are common in modern society even during the early stages of life, have unfavorable effects on brain function. Altered brain function can cause problem behaviors later in life, such as truancy from or dropping out of school, quitting employment, and committing suicide. In this review, we discuss findings from several large cohort studies together with recent results of a cohort study using the marshmallow test, which was first introduced in the 1960s. This test assessed the ability of four-year-olds to delay gratification and showed how this ability correlated with success later in life. The role of the serotonergic system in sleep and how this role changes with age are also discussed. The serotonergic system is involved in reward processing and interactions with the dorsal striatum, ventral striatum, and the prefrontal cortex are thought to comprise the neural basis for behavioral patterns that are affected by the quantity, quality, and timing of sleep early in life. PMID:26840337

  14. Ultrasonic flaw detection using radial basis function networks (RBFNs).

    Science.gov (United States)

    Gil Pita, R; Vicen, R; Rosa, M; Jarabo, M P; Vera, P; Curpian, J

    2004-04-01

    Ultrasonic flaw detection has been studied many times in the literature. Schemes based on thresholding after a previous matched filter use to be the best solution, but results obtained with this method are only satisfactory when scattering and attenuation are not considered. In this paper, we propose an alternative solution to thresholding detection method. We deal with the usage of different flaw detection methods comparing them with the proposed one. The experiment tries to determinate whether a given ultrasonic signal contains a flaw echo or not. Starting with a set of 24,000 patterns with 750 samples each one, two subsets are defined for the experiments. The first one, the training set, is used to obtain the detection parameters of the different methods, and the second one is used to test the performance of them. The proposed method is based on radial basis functions networks, one of the most powerful neural network techniques. This signal processing technique tries to find the optimal decision criterion. Comparing this method with thresholding based ones, an improvement over 25-30% is obtained, depending on the probability of false alarm. So our new method is a good alternative to flaw detection problem.

  15. Radial basis function networks GPU-based implementation.

    Science.gov (United States)

    Brandstetter, Andreas; Artusi, Alessandro

    2008-12-01

    Neural networks (NNs) have been used in several areas, showing their potential but also their limitations. One of the main limitations is the long time required for the training process; this is not useful in the case of a fast training process being required to respond to changes in the application domain. A possible way to accelerate the learning process of an NN is to implement it in hardware, but due to the high cost and the reduced flexibility of the original central processing unit (CPU) implementation, this solution is often not chosen. Recently, the power of the graphic processing unit (GPU), on the market, has increased and it has started to be used in many applications. In particular, a kind of NN named radial basis function network (RBFN) has been used extensively, proving its power. However, their limiting time performances reduce their application in many areas. In this brief paper, we describe a GPU implementation of the entire learning process of an RBFN showing the ability to reduce the computational cost by about two orders of magnitude with respect to its CPU implementation.

  16. A growing and pruning method for radial basis function networks.

    Science.gov (United States)

    Bortman, M; Aladjem, M

    2009-06-01

    A recently published generalized growing and pruning (GGAP) training algorithm for radial basis function (RBF) neural networks is studied and modified. GGAP is a resource-allocating network (RAN) algorithm, which means that a created network unit that consistently makes little contribution to the network's performance can be removed during the training. GGAP states a formula for computing the significance of the network units, which requires a d-fold numerical integration for arbitrary probability density function p(x) of the input data x (x in R(d)) . In this work, the GGAP formula is approximated using a Gaussian mixture model (GMM) for p(x) and an analytical solution of the approximated unit significance is derived. This makes it possible to employ the modified GGAP for input data having complex and high-dimensional p(x), which was not possible in the original GGAP. The results of an extensive experimental study show that the modified algorithm outperforms the original GGAP achieving both a lower prediction error and reduced complexity of the trained network.

  17. ESTIMATION OF INFLATION ON THE BASIS OF INDEPENDENT INFORMATION

    Directory of Open Access Journals (Sweden)

    Orlov A. I.

    2015-04-01

    Full Text Available This article is devoted to the investigations of our research team built for independent collection and examination the information about prices, ie to study the real inflation. The approach to measuring the rise in prices is based on selecting and fixing tool of economists and managers - the consumer basket which does not change during the time. On the basis of physiological consumption norms of the Institute of Nutrition (Russian Academy of medical Sciences we made up the minimum consumer basket, ie we set annual consumption on food staples required to maintain normal functioning of the human body. In 1993-2015 we carried out an independent price collection. We obtained values of the consumer basket and inflation indices. We give the comparison with the data of official statistics. Our work is aimed at the elimination of Rosstat's monopoly in calculating the index of inflation, the minimum subsistence level and the real disposable income of the population. Using the same consumer basket makes it possible to compare the results of calculations for different time periods. That is why our works compare favorably to the approach of the official statistics. We have given a more detailed analysis of inflation in the XXI century. We have also briefly reviewed the use of inflation indices in the analysis of problems of households, organizations and production firms, as well as the country as a whole

  18. Genetic basis for glandular trichome formation in cotton.

    Science.gov (United States)

    Ma, Dan; Hu, Yan; Yang, Changqing; Liu, Bingliang; Fang, Lei; Wan, Qun; Liang, Wenhua; Mei, Gaofu; Wang, Lingjian; Wang, Haiping; Ding, Linyun; Dong, Chenguang; Pan, Mengqiao; Chen, Jiedan; Wang, Sen; Chen, Shuqi; Cai, Caiping; Zhu, Xiefei; Guan, Xueying; Zhou, Baoliang; Zhu, Shuijin; Wang, Jiawei; Guo, Wangzhen; Chen, Xiaoya; Zhang, Tianzhen

    2016-01-01

    Trichomes originate from epidermal cells and can be classified as either glandular or non-glandular. Gossypium species are characterized by the presence of small and darkly pigmented lysigenous glands that contain large amounts of gossypol. Here, using a dominant glandless mutant, we characterize GoPGF, which encodes a basic helix-loop-helix domain-containing transcription factor, that we propose is a positive regulator of gland formation. Silencing GoPGF leads to a completely glandless phenotype. A single nucleotide insertion in GoPGF, introducing a premature stop codon is found in the duplicate recessive glandless mutant (gl2gl3). The characterization of GoPGF helps to unravel the regulatory network of glandular structure biogenesis, and has implications for understanding the production of secondary metabolites in glands. It also provides a potential molecular basis to generate glandless seed and glanded cotton to not only supply fibre and oil but also provide a source of protein for human consumption. PMID:26795254

  19. Neural Basis of Brain Dysfunction Produced by Early Sleep Problems

    Directory of Open Access Journals (Sweden)

    Jun Kohyama

    2016-01-01

    Full Text Available There is a wealth of evidence that disrupted sleep and circadian rhythms, which are common in modern society even during the early stages of life, have unfavorable effects on brain function. Altered brain function can cause problem behaviors later in life, such as truancy from or dropping out of school, quitting employment, and committing suicide. In this review, we discuss findings from several large cohort studies together with recent results of a cohort study using the marshmallow test, which was first introduced in the 1960s. This test assessed the ability of four-year-olds to delay gratification and showed how this ability correlated with success later in life. The role of the serotonergic system in sleep and how this role changes with age are also discussed. The serotonergic system is involved in reward processing and interactions with the dorsal striatum, ventral striatum, and the prefrontal cortex are thought to comprise the neural basis for behavioral patterns that are affected by the quantity, quality, and timing of sleep early in life.

  20. The physicochemical basis of QSARs for baseline toxicity.

    Science.gov (United States)

    Mackay, D; Arnot, J A; Petkova, E P; Wallace, K B; Call, D J; Brooke, L T; Veith, G D

    2009-01-01

    The physico-chemical properties relevant to the equilibrium partitioning (bioconcentration) of chemicals between organisms and their respired media of water and air are reviewed and illustrated for chemicals that range in hydrophobicity. Relationships are then explored between freely dissolved external concentrations such as LC50s and chemical properties for one important toxicity mechanism, namely baseline toxicity or narcosis. The 'activity hypothesis' proposed by Ferguson in 1939 provides a coherent and compelling explanation for baseline toxicity of chemicals in both water- and air-respiring organisms, as well as a reference point for identifying more specific toxicity pathways. From inhalation studies with fish and rodents, narcosis is shown to occur at a chemical activity exceeding approximately 0.01 and there is no evidence of narcosis at activities less than 0.001. The activity hypothesis provides a framework for directly comparing the toxic potency of chemicals in both air- and water-breathing animals. The activity hypothesis is shown to be consistent with the critical body residue concept, but it has the advantage of avoiding the confounding effect of lipid content of the test organism. It also provides a theoretically sound basis for assessing the baseline toxicity of mixtures. It is suggested that since activity is readily calculated from fugacity, observed or predicted environmental abiotic and biotic fugacities can be used to evaluate the potential for baseline toxicity. Further, models employing fugacity or activity can be used to improve the experimental design of bioassays, thus possibly reducing unnecessary animal testing. PMID:19544198