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Sample records for basin formaciones favorables

  1. Favourable Formations for CO{sub 2} Storage in the Almazan Basin; Formaciones Favorables para el Almacenamiento de CO{sub 2} en la Cuenca de Almazan

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Rivas, C.; Lomba Falcon, L.

    2008-04-10

    Geological storage of carbon dioxide is one of the technological options that have been considered nowadays for global climate change mitigation. Underground CO{sub 2} storage requires the selection and identification of deep geological formations which must meet criteria for health and environmental safety in the middle-term of one thousand years. Deep permeable formations, depleted oil and gas fields, unminable coal seams and saline rocks are possible geological formations for CO{sub 2} storage. Some areas in our country have been selected to search potential CO{sub 2} reservoirs. Among these areas, sedimentary basins are highlighted because of their thick stratigraphic sequences and the availability of extensive geological data which are coming from fossil fuel exploration. In this report, the identification and selection of favourable geological formations in the Almazan basin is presented. A 3D simplified subsurface basin geological model that was based on a Geographic Information System is included as well. The report also includes suitable CO{sub 2} injection areas in the surface for the selected geological formations. Finally, a preliminary CO{sub 2} storage capacity estimation of a potential structural trap has been calculated, considering only physical CO{sub 2} trapping. This work has been undertaken in the framework of the Geological CO{sub 2} Storage Project which is within the Singular Strategic Project of the Ministry of Education and Science Generation, Capture and Storage advanced technologies of CO{sub 2}. (Author) 84 refs.

  2. Underground CO{sub 2} Storage: Approach for Favourable Formations in Ebro Basin; AGP de CO{sub 2}: Seleccion de Formaciones Favorables en la Cuenca del Ebro

    Energy Technology Data Exchange (ETDEWEB)

    Campos, R.; Perucha, A.; Recreo, F.

    2008-04-10

    The study of the possibilities of conducting Deep Geological CO{sub 2} Storage inside Spanish territory is being performed through the Strategic Singular Project PS-120000-2005-2 of the National Program of Energy from the Education and Science Ministry, and called CO{sub 2} generation, sequestration and storage advanced technologies, sub project N3 CO{sub 2} Geological Storage This report studies the possibilities the Ebro basin offers for definitive CO{sub 2} storage as one of the Spanish selected areas from previous studies. The study and reinterpretation of the information obtained from the hydrocarbon exploration accomplished in the area has lead to the selection of a series of geological formations. These formations have been chosen attending certain characteristics such as their disposition, extension, depth and porosity. The study has also been conducted considering the characteristics of the geological formations above the CO{sub 2} storage formations so as to guarantee the sealing of the storage. The study includes the approximate estimation of the storage capacity for each of the formations in Megatons of CO{sub 2}, which can be useful in future decision making. Deep geological storage is one of the more relevant international initiatives in order to eliminate or reduce the anthropogenic CO{sub 2} emissions to the atmosphere. (Author) 68 refs.

  3. Modelling of the Duero Sedimentary Basin and Selection of Deep Favourable Geological Formations for Supercritical CO{sub 2} Storage; Modelizacion del Subsuelo de la Cuenca del Duero y Seleccion de Formaciones Favorables para el Almacenamiento de CO{sub 2} en Estado Supercritico

    Energy Technology Data Exchange (ETDEWEB)

    Prado, A. J.; Perez del Villar, L.; Pelayo, M.; Recreo, F.

    2008-04-10

    Currently, the Deep Geological Storage is the internationally most accepted option to store CO{sub 2}, whose main goal is to reduce the CO{sub 2} emissions to the atmosphere. This work, which has been carried out in the frame of The Strategic Singular Project entitled: CO{sub 2} generation, capture and storage advanced technologies summarizes a general methodology focused on the selection and modelling of favourable formations to store CO{sub 2} and to estimate their storage capacity. To conclude, the Duero basin suitability to allocate a CO{sub 2} storage plant has been quantified by integrating the Multi-criteria Evaluation Methods with the corresponding developed Geographical Information Systems. (Author) 45 refs.

  4. Significance of new breakthrough in and favorable targets of gas exploration in the Middle Permian system, Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Ping Shen

    2015-11-01

    Full Text Available The Middle Permian system in the Sichuan Basin represents favorable conditions for the formation of natural gas reservoirs. However, only fracture-vuggy limestone gas reservoirs were discovered in early exploration, whose scales and results were limited. In 2014, a high-yield industrial gas flow was produced there in Well Shuangtan 1, the major risk-exploration well, which means a great breakthrough in natural gas exploration in the Middle Permian system, Sichuan Basin. This plays a strategically important and guiding role in oil and gas exploration in ultra-deep marine formations. This paper illustrates the deployment background of Well Shuangtan 1, major exploration achievements and its significance in the gas exploration in the Middle Permian system, Sichuan Basin. Moreover, exploration potential and subsequent exploration targets of Middle Permian are analyzed in terms of its hydrocarbon source conditions, sedimentary characteristics, reservoir characteristics and areal extension, resources and favorable exploration zones. It is concluded that the Middle Permian system in the Sichuan Basin is a continent-connected carbonate platform with carbonate deposits being dominant. There are three types of reservoirs, including pore dolomite, karst fracture-vuggy, and fracture, which present considerable natural gas resources and huge exploration potential. Favorable exploration zones classification of Middle Permian in the Sichuan Basin indicates that the most favorable exploration zones are mainly distributed in the central-western Sichuan Basin. In particular, the northwestern Sichuan Basin is the most favorable exploration area which is characterized by the most excellent hydrocarbon source conditions, developed dolomite reservoirs and zonal distribution of structures.

  5. The Genetic Mechanism and Model of Deep-Basin Gas Accumulation and Methods for Predicting the Favorable Areas

    Institute of Scientific and Technical Information of China (English)

    WANG Tao; PANG Xiongqi; MA Xinhua; JIN Zhijun; JIANG Zhenxue

    2003-01-01

    As a kind of abnormal natural gas formed with special mechanism, the deep-basin gas, accumulated in thelower parts of a basin or syncline and trapped by a tight reservoir, has such characteristics as gas-water inversion, abnormalpressure, continuous distribution and tremendous reserves. Being a geological product of the evolution of petroliferousbasins by the end of the middle-late stages, the formation of a deep-basin gas accumulation must meet four conditions, i.e.,continuous and sufficient gas supply, tight reservoirs in continuous distribution, good sealing caps and stable structures.The areas, where the expansion force of natural gas is smaller than the sum of the capillary force and the hydrostaticpressure within tight reservoirs, are favorable for forming deep-basin gas pools. The range delineated by the above twoforces corresponds to that of the deep-basin gas trap. Within the scope of the deep-basin gas trap, the balance relationshipbetween the amounts of ingoing and overflowing gases determines the gas-bearing area of the deep-basin gas pool. The gasvolume in regions with high porosity and high permeability is worth exploring under current technical conditions and it isequivalent to the practical resources (about 10%-20% of the deep-basin gas). Based on studies of deep-basin gasformation conditions, the theory of force balance and the equation of material balance, the favorable areas and gas-containing ranges, as well as possible gas-rich regions are preliminarily predicted in the deep-basin gas pools in the UpperPaleozoic He-8 segment of the Ordos basin.

  6. Development of the Cerro solo deposit and uranium favorability of the San Jorge Gulf Basin, province of Chubut

    International Nuclear Information System (INIS)

    In the future the uranium exploration activities of CNEA would tend to improve the knowledge of geology and uranium favorability; to perform prospection tasks, and research and development in exploration technologies, to contribute to be in a position to meet the requirements of the country in the long term. On the other hand, a strong growth of nuclear capacity is expected in the first two decades of the next century. Based on its promising grade, the Cerro Solo uranium ore deposit was selected in 1990 by the CNEA to carry out an assessment project. The intensive exploration level was accomplished, as follows: definition of general characteristics of the main orebodies; detailed geologic studies; estimation of resources with adequate data; and preliminary selection of mining-milling methods to estimate the potential profitability of the project. The deposit belongs to the sandstone type. The mineralized layers are distributed into the fluvial sandstones and conglomerates of the cretaceous Chubut Group, lying 50 to 130 m deep Resources of the deposit, with an average grade of 0.3% U, in tonnes of recoverable uranium at costs of up to $80/kg U, are: Reasonable Assured Resources (RAR): 800 t U, Estimated Additional Resources, Category I (EAR-I): 2100 t U. Follow-up drilling programmes are being performed at present in some of the target sites defined in the paleochannel that hosts the Cerro Solo deposit, in order to establish the hypothetical resources of the area. The sites were determined as a result of the exploration that CNEA conducted in the Pichinan uranium district. Recently a regional research project was formulated, for the detailed exploration in the San Jorge Gulf Basin, where the Chubut Group is distributed. 17 refs, 4 figs

  7. High resolution heliborne magnetic data - an aid to delineate favorable basement structures for uranium exploration in parts of Palnad and Srisailam sub-basins, Cuddapah Basin, India

    International Nuclear Information System (INIS)

    High resolution heliborne magnetic survey carried out by Atomic Minerals Directorate for Exploration and Research over an area of 2500 sq km covering parts of Srisailam and Palnad Sub-basins along the northern part of the Cuddapah Basin has brought out number of important magnetic domains, structures and basement configuration hitherto unknown. N-S to NNE-SSW and ENE-WSW basement faults/fractures were delineated in parts of Srisailam and Palnad Sub-basins respectively. These fractures are also associated with mafic intrusives and exhibit lithostructural setup similar to Peddagattu, Lambapur and Koppunuru uranium deposits. In central part, N-S trending magnetic anomalies associated with gravity gradient deciphered as a regional fault passing through Damarcherla, Pondugala and Gurajala. Macherla gravity high associated with NW-SE trending intense magnetic anomalies is interpreted as Banded Iron Formation (BIF). Present study led to the delineation of structural features transecting the sediments which may form important locale for unconformity related uranium mineralization. (author)

  8. Integrated interpretation of satellite imagery, aeromagnetic, aeroradiometric and ground exploration data-sets to delineate favorable target zones for unconformity related uranium mineralization, Khariar Basin, Central India

    International Nuclear Information System (INIS)

    margin of Khariar basin are also characterized by presence of paleosol at unconformity, which are favorable factors for unconformity type uranium mineralization. Based on the present study, part of western and southern margin emerge as potential target areas for further exploration of uranium. (author)

  9. Control of Facies and Potential on Jurassic Hydrocarbon Accumulation and Prediction of Favorable Targets in the Hinterland Region of the Junggar Basin

    Institute of Scientific and Technical Information of China (English)

    CHEN Dongxia; PANG Xiongqi; KUANG Jun; KANG Dejiang; LEI Lei; DENG Yougen

    2010-01-01

    Exploration practices show that the Jurassic System in the hinterland region of the Junggar Basin has a low degree of exploration but huge potential,however the oil/gas accumulation rule is very complicated,and it is difficult to predict hydrocarbon-bearing properties.The research indicates that the oil and gas is controlled by structure facies belt and sedimentary system distribution macroscopically,and hydrocarbon-bearing properties of sand bodies are controlled by lithofacies and petrophysicai facies microscopically.Controlled by ancient and current tectonic frameworks,most of the discovered oil and gas are distributed in the delta front sedimentary system of a palaeo-tectonic belt and an ancient slope belt.Subaqueous branch channels and estuary dams mainly with medium and fine sandstone are the main reservoirs and oil production layers,and sand bodies of high porosity and high permeability have good hydrocarbon-bearing properties; the facies controlling effect shows a reservoir controlling geologic model of relatively high porosity and permeability.The hydrocarbon distribution is also controlled by relatively low potential energy at the high points of local structure macroscopically,while most of the successful wells are distributed at the high points of local structure,and the hydrocarbon-bearing property is good at the place of relatively low potential energy; the hydrocarbon distribution is in close connection with faults,and the reservoirs near the fault in the region of relatively low pressure have good oil and gas shows; the distribution of lithologic reservoirs at the depression slope is controlled by the distribution of sand bodies at positions of relatively high porosity and permeability.The formation of the reservoir of the Jurassic in the Junggar Basin shows characteristics of favorable facies and low-potential coupling control,and among the currently discovered reservoirs and industrial hydrocarbon production wells,more than 90% are developed within

  10. Petroleum Geology in the Tarim, Junggar and Turpan-Hami Basins Showing Favorable Conditions for the Occurrence of Large and Medium Oil and Gas Fields

    Institute of Scientific and Technical Information of China (English)

    Tian Zaiyi; Zhang Qingchun

    1994-01-01

    @@ The three main sedimentary basins, Tarim, Junggar and Turpan-Hami in the northwestern part of China are composite basins with different tectonic settings formed in various periods, stacking one on the other through their evolutionary history. Since polycyclic evolution is involved in their development,these basins are characterized by polyphase of hydrocarbon generation, multi-passage for hydrocarbon migration,multi-reservoir for hydrocarbon accumulation and multi-type of oil and gas pools with multi- controlling factors.

  11. Asociaciones palinológicas en las formaciones Los Monos (Devónico e Itacua (Carbonífero Inferior en Balapuca (Cuenca Tarija, sur de Bolivia: Parte 2. Asociaciones de la Formación Itacuae interpretación estratigráfica y cronología de las formaciones Los Monos e Itacua Palynological assemblages present in Los Monos (Devonian and Itacua (Early Carboniferous formations at Balapuca (Tarija basin, southern Bolivia: Part 2. Itacua Formation assemblages and stratigraphical interpretation and chronology of the Los Monos and Itacua formations

    Directory of Open Access Journals (Sweden)

    Mercedes di Pasquo

    2007-07-01

    Full Text Available Se presenta el resultado palinológico de tres muestras fértiles de la Formación Itacua, la cual aflora en la localidad de Balapuca ubicada en la margen boliviana del río Bermejo, en la sierra de San Telmo. La extensión estratigráfica de las especies determinadas en esta asociación permitió identificar dos conjuntos de palinomorfos, uno autóctono compuesto por 61 especies de esporas y escasas colonias de Botryococcus, y otro conjunto de especies retrabajadas conformado por esporas, acritarcas, prasinofitas, algas clorofíceas, criptosporas y quitinozoarios, en su mayoría procedentes de capas del Devónico y subordinadas esporas del Tournaisiano (Carbonífero. Dos especies de esporas autóctonas se proponen como nuevas combinaciones. La distribución estratigráfica de especies autóctonas claves permitió asignar dicha asociación al Viséano temprano (Carbonífero Temprano. Se trata del primer trabajo donde se ¡lustran por primera vez palinomorfos de esta antigüedad (así como una selección de especies retrabajadas obtenidos de un depósito in situ de la Formación Itacua presente en la parte sur de la Cuenca Tarija. Sobre la base de la edad atribuida a las formaciones Los Monos e Itacua en este estudio, queda definido un hiato entre ellas, caracterizado por un lapso erosivo en el Frasniano-Tournaisiano y otro no depositacional durante el Famenniano tardío ('Struniano', basado en la presencia/ausencia en la asociación de la Formación Itacua de especies de palinomorfos retrabajados con extensión estratigráfica restringida. Por otra parte, sobreyacen a esta unidad sedimentitas del Grupo Macharetí datadas con palinología como del Carbonífero Tardío temprano. Entre ambas unidades se registra un nuevo hiato que abarca el Viséano tardío-Serpukhoviano interpretado en parte como no depositacional. Se incluye, además, una discusión sobre las principales causas de ambos hiatusThe palynological result of three fertile samples of

  12. Las formaciones Plio-Cuaternarias de El Abalario, en el litoral de la provincia de Huelva

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    Salvany, J. M.

    2010-12-01

    Full Text Available The study of new and ancient boreholes in El Abalario area (Lower Guadalquivir basin permitted to identify four main plio-quaternary formations above the Miocene marls, namely: Huelva Sands, Bonares Sands, Almonte Sands and Gravels, and El Abalario Sands. Respectively, they are interpreted as shallow marine, deltaic, alluvial and eolian sediments, together forming a marine to continental sequence that reaches a thickness of more than 250 metres. All sediments are arranged as a gentle dipping and thickening structure to the southeast. Only a few boreholes of the western border of El Abalario reach the top of the Miocene marls. In the rest of the Abalario area the Miocene marls are confined to an unknown level bellow the deepest boreholes. Upward, the marls grade to the Huelva sands, without any appreciable break in the sediments. To the north, the upper part of the Huelva formation grades to the Bonares sands, which is mainly developed outside the study area. Both formations are covered by the coarse clastic deposits of the Almonte formation. At the top, El Abalario sands recover all previous deposits and configure the current relief. The study performs the early existing geology profile and the connection with the surrounding areas.

    El estudio de nuevos y antiguos sondeos en El Abalario (Bajo Guadalquivir permite identificar por encima de las margas miocenas, cuatro principales formaciones plio-cuaternarias, denominadas: Fm. Arenas de Huelva, Fm. Arenas de Bonares, Fm. Arenas y Gravas de Almonte, y Fm. Arenas de El Abalario, respectivamente interpretadas como sedimentos marinos someros, deltaicos, aluviales y eólicos. En conjunto forman una potente sucesión de más 250 metros de espesor, de estructura ligeramente inclinada y de espesor creciente hacia el sureste. Sólo algunos sondeos de la parte occidental de El Abalario alcanzan las margas miocenas. En el resto del área de El Abalario, las margas están a una profundidad desconocida

  13. Favorable exploration targets in northern Avat and northern Shuntuoguole areas, Tarim Basin%塔里木盆地阿瓦提北—顺托果勒北地区有利勘探方向分析

    Institute of Scientific and Technical Information of China (English)

    吕海涛; 耿锋; 毛庆言; 伍齐乔; 贺凯

    2012-01-01

    In the past years, few achievements in accordance with the scale of hydrocarbon generation depression have been obtained in petroleum explorations in Avat area of the Tarim Basin and the favorable exploration targets still remain exploring. Based on new exploration data and research progresses, it is discussed in this paper the petroleum geologic conditions in the northern Avat and the northern Shuntuoguole areas. Three petroleum systems have been identified according to petroleum system theory. As to the Cambrian-Ordovician petroleum system ( I) in Avat area, the most favorable exploration target is the middle-lower Ordovician karst-vuggy carbonate reservoir in the east of the study area. The traps formed in or before Yanshan period along big faults are less favorable. For the Triassic -Jurassic petroleum system ( \\) in Kuche area, the most favorable exploration targets include Paleogene-Cretaceous lithologic traps and various traps of unconformity fluctuation of early Himalayan epoch in the east of the area. Delta sandbody and lacustrine turbidite mass are favorable targets in the Triassic petroleum system (?) in Avat area.%塔里木盆地阿瓦提断陷长期以来未能取得与生烃坳陷相对应的油气勘探成果,勘探部署方向正处于探索之中.结合近期勘探取得的资料和新的研究进展,综合分析了阿瓦提北—顺托果勒北地区的石油地质条件,从含油气系统的角度,指出了阿瓦提寒武—奥陶系含油气系统(!)的最有利目标为研究区东部的中下奥陶统碳酸盐岩缝洞型储集体,其次为顺大断裂带分布并在燕山期及以前定型的圈闭;库车三叠—侏罗系含油气系统(!)的有利目标为研究区东部白垩系、古近系岩性圈闭和喜山早期不整合面上下的各类圈闭;阿瓦提三叠系含油气系统(?)有利方向为三叠系近烃源岩三角洲砂体、湖相浊积岩体.

  14. Corales, formaciones arrecifales y blanqueamiento de 1987 en Bahía Portete (Guajira, Colombia)

    OpenAIRE

    Solano-P., Oscar D.

    1994-01-01

    Para el reconocimiento y caracterización de las formaciones arrecifales de Bahía Pórtete se visitaron un total de 22 estaciones entre junio de 1987 y enero de I988. Se registraron por primera vez Acropora cervicomis, Agaricia agaricites, Montastrea cavernosa, Diploría clivosa e Isophyllia sinuosa, elevando a 18 el número de especies de escleractinios de la bahía. El componente principal por su abundancia y diversidad de formas fue el hidrocoral Millepora alcicomis. Las formaciones arrecifales...

  15. Handling Gifts, Gratuities, and Favors.

    Science.gov (United States)

    Eastmond, Nick; Jones, Mark

    1993-01-01

    The twelfth in a series of articles featuring the principles of the AECT (Association for Educational Communications and Technology) Code of Professional Ethics focuses on the acceptance by professors of gratuities, gifts, or favors that might impair or appear to impair professional judgment. (LRW)

  16. "Nuestra lucha recién comienza": Vivencias de Pertenencia y Formaciones Mapuche de Sí Mismo

    Directory of Open Access Journals (Sweden)

    Claudia Briones

    2007-03-01

    Full Text Available Este artículo apunta a mostrar que el concepto de identidad e incluso el de su politización no son más que una punta de iceberg para entender procesos mucho más complejos de individuación y comunalización que tornan diverso y a la vez ensamblan lo que se entiende y siente en torno a "ser mapuche hoy". Para ello se exploran factores que influyen en la diversificación de propuestas y respuestas al momento de fijar o aceptar políticas culturales para visibilizar al Pueblo Mapuche, haciendo foco en reflexiones y posicionamientos de los pu wece o jóvenes y en los diálogos explícitos e implícitos de crítica o apego que mantienen con otras perspectivas. El análisis se apoya en algunos conceptos explicativos anidados (formaciones nacionales y provinciales de alteridad, geografías estatales de exclusión/inclusión, movilidades estructuradas, aboriginalidad que se han desarrollado en trabajos anteriores, e introduce el de formaciones Mapuche de sí, en tanto articulaciones no azarosas de individuación en términos de subjetividad, identidad y agencia.This article aims at showing that the concept of identity, including its politicization, is no more than the tip of the iceberg for understanding much more complicated processes of individuation and communalization that diversify, and at the same time assemble, what is understood and felt as "being Mapuche today". To do so, it explores factors that influence the diverse proposals and responses that arise in Mapuche cultural politics, focusing on pu wece, or young people's, reflections and positionalities. For this analysis, I use some specific concepts (national and provincial formations of alterity, state geographies of inclusion/exclusion, structured mobilities, aboriginality that have been developed in previous works, and introduce the concept of Mapuche formations of self as structured and structuring articulations of individuality in terms of subjectivity, identity and agency.

  17. Geografía ecológica del departamento de antioquia (zonas de vida (formaciones vegetales) del departamento de antioquia)

    OpenAIRE

    Espinal T. Luis Sigifredo

    2012-01-01

    Se presenta en este trabajo un estudio del Departamento de Antioquia, de acuerdo con el sistema Hildridge para la clasificación de las formaciones vegetales. La formación, según Holdridge, es la división más grande de vegetación, está determinada por la interacción de la precipitación y la biotemperatura y se caracteriza por su fisonomía. Las formaciones vegetales que se encuentran en Antioquia se identificaron en el campo por la fisonomía de la vegetación natural. Para esto fue nec...

  18. FAVORED ZODIAC FOR CELEBRITY BIRTHS

    Directory of Open Access Journals (Sweden)

    Miah M. Adel

    2013-01-01

    Full Text Available To find any favored zodiac sign for celebrity births, a sample of 100 celebrities were randomly selected from people of different walks of life. The sample contained politicians, natural scientists, social scientists, Authors of literary works, social workers, humanitarian workers, business personnel, sports icons, singers, actors, actresses, etc. etc. from history and from the current time. The zodiac signs for the celebrities were found from their known dates of births. In the analysis of data, zodiac signs and the number of celebrities were represented as the independent x and the dependent y variables, respectively. For academic interests for the 9th grade high school juniors (at the time of the project performance, the co-authors of this article, as well as for the potentially illustrative uses in high school mathematics textbooks, bar and scatter plots were made, the line of best-fit and the equation of the line were found, probabilities of occurrences of celebrities for each of the zodiac signs were calculated and the correlation coefficients between the variables were determined for the sample. It was found that the zodiac Aquarius has the largest number of celebrities in the sample and that the two variables are moderately correlated. The sample sizes which were increased to 200 and then 300. By including another 100 more celebrities to find if the trend remains unchanged. In all the three cases, Aquarius turned out to be the zodiac when most of the celebrities are born.

  19. El Lenguaje, el Chiste y el Espíritu: Sobre la Estructura de las Formaciones En Jacques Lacan

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    Gianfranco Cattaneo Rodríguez

    2012-01-01

    Full Text Available Desde la definición del inconsciente propuesta por Jacques Lacan, el inconsciente está estructurado como un lenguaje, el presente artículo – que es parte de una investigación titulada “Genealogía del objeto a” en la obra de Jacques Lacan desde el paradigma del caso clínico, del fondo de investigación “Jorge Millas” de la Vicerrectoría de Investigación y Doctorado de la Universidad Andrés Bello – tiene por objetivo analizar la estructura de dicha fórmula y exponer sus consecuencias para una clínica de las formaciones del inconsciente que, por sostenerse en la estructura del lenguaje, sea coherente con la elaboración conceptual del psicoanálisis. Porque, para hablar de forma válida de las funciones creadoras ejercidas por la estructura del significante sobre el significado, como indica Lacan, no hay que hablar simplemente de la palabra, sino hablar siguiendo el hilo mismo de la palabra para evocar sus propias funciones. Este es el modo como la verdad del sujeto se devela en las formaciones del inconsciente, y el chiste cumple un papel fundamental para Lacan, ya que el es la revelación del fondo, del abismo del lenguaje, desde la contingencia del sin-sentido; contingencia que muestra la fuerza de la articulación significante y por la cual el sujeto debe comprometerse al tomar la palabra y ubicarse respecto del sentido, en el ejercicio del sin-sentido.

  20. Estratigrafía Cuantitativa de las Formaciones Tablazo y Simití en las localidades de Sáchica (Boyacá y Barichara - San Gil (Santander, Colombia Estratigrafía Cuantitativa de las Formaciones Tablazo y Simití en las localidades de Sáchica (Boyacá y Barichara - San Gil (Santander, Colombia

    Directory of Open Access Journals (Sweden)

    Moreno Giovanni

    2002-12-01

    Full Text Available This paper will discuss the stratigraphic sections, petrographic and sedimentary environment of Tablazo and Simití formation in sections of Barichara - San Gil (Santander and Sachica (Boyacá, with a review of the stratigraphic nomenclature. The Tablazo Formation is mainly comprised of shallow deposits marked with bioclastic fragments. Proximal offshore deposits characterize Simiti Formation with sporadic formation influenced by the shallow coastal environment  The variation thickness of cycles (parasecuences and accumulated thickness of cycles mark the trans-generational behavior of the accommodation space. The cycles generated in Barichara San Gil (Santander are thirty percent (30% below average when compared to Sachica (Boyaca.  This concludes that the lirst cycles were deposited in a shallower environment. The basin is shown to have a relative slope of  0.067 degrees lacing south. The curves of Accumulated Deviation of Thickness Average or Fisher diagram shown lor Tablazo and Simiti formations in two sections register transgeneration of the accommodation space. The variation of curves registers tendencies of the successions and can constitute a valuable tool for the delimitation of the lithological segments.  The stratigraphic data from the present study and use of the spectral analysis of Fourier demonstrate cycles measured in the observed units.  Results show a periodicity of fifty meters (50m in Sachica and twenty-six meters (26m in Barichara, which can be interpreted as following the orbital parameter of Milankovitch, thus corresponding to its long eccentricity (400ka. Using the orbital indexes, the calculated rate of deposit is 12.7cm/ka in Sachica and 6.5cm/ka in Barichara-San Gil for the Tablazo Formation and Simiti Formation.Se presentan las columnas estratigráficas, petrografía y ambientes de depósito de las Formaciones Tablazo y Simití en las secciones de Barichara - San Gil ( Santander y Sáchica (Boyacá, con una revisi

  1. Magnetic survey for identifying favorable zone

    International Nuclear Information System (INIS)

    This survey describes the ability of magnetic methods in identifying the zone conductor associated with mineral magnetite, pyrite, ilmenite and pyrrhotite. Large magnetic anomalies strongly influenced by the induction of ferromagnetic mineral. From the 2D modeling results can be interpreted that the favorable zone associated with the mineral magnetite, pyrite, ilmenite and pyrrhotite. This model obtained favorable dimensions of the width of between 50 to 75 meters, thickness of between 67 to 75 meters and a depth of 12 meters. (author)

  2. El diacronismo entre las Formaciones Tordillo y Quebrada del Sapo (Kimeridgiano en el sector sur de la cuenca neuquina

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    Carlos Zavala

    2008-12-01

    Full Text Available Las Formaciones Tordillo y Quebrada del Sapo corresponden a unidades clásticas acumuladas en un medio continental dentro de la cuenca Neuquina durante el Kimeridgiano. En el área de estudio, estas unidades se disponen en contacto neto sobre depósitos marinos a continentales del Grupo Lotena (Caloviano Medio - Oxfordiano y son a su vez cubiertas por los depósitos marinos de la Formación Vaca Muerta (Titoniano. De acuerdo a su posición en la secuencia, estas unidades han sido consideradas como equivalentes por diversos autores, aunque las relaciones de contacto entre las mismas no habían sido documentadas hasta el presente. Relevamientos detallados de campo efectuados entre la sierra de Chacaico y la Quebrada del Sapo han permitido identificar por primera vez un afloramiento donde se exponen adecuadamente las relaciones estratigráficas entre estas dos unidades. En el mismo puede observarse que las Formaciones Tordillo y Quebrada del Sapo son diacrónicas, y se encuentran limitadas por una importante discordancia erosiva (superficie de deflación la cual tendría además un significado tectónico. La Formación Tordillo sería más antigua, y habría sido depositada con anterioridad a una importante fase de deformación tectónica con una consecuente inversión del relieve. El pasaje hacia la Formación Quebrada del Sapo ocurre mediante una discordancia de erosión tapizada por ventifactos, la cual hace desaparecer totalmente a la Formación Tordillo hacia el este en poco más de 600 m. Sobre esta discontinuidad se abren progresivamente los depósitos de la Formación Quebrada del Sapo. La depositación de esta unidad habría ocurrido sobre un relieve de bajos de deflación, labrados sobre las pelitas de la Formación Lotena.

  3. Basin Hopping Graph

    DEFF Research Database (Denmark)

    Kucharik, Marcel; Hofacker, Ivo; Stadler, Peter;

    2014-01-01

    folding free energy landscape, however, can provide the relevant information. Results We introduce the basin hopping graph (BHG) as a novel coarse-grained model of folding landscapes. Each vertex of the BHG is a local minimum, which represents the corresponding basin in the landscape. Its edges connect...... basins when the direct transitions between them are “energetically favorable”. Edge weights endcode the corresponding saddle heights and thus measure the difficulties of these favorable transitions. BHGs can be approximated accurately and efficiently for RNA molecules well beyond the length range...

  4. Subsurface stratigraphy and uranium--vanadium favorability of the Morrison Formation, Sage Plain Area, southeastern Utah and southwestern Colorado

    International Nuclear Information System (INIS)

    The four members of the Morrison Formation that are recognizable in the area studied are, in ascending order, the Salt Wash, Recapture, Westwater Canyon, and Brushy Basin. The Salt Wash member has the highest uranium favorability of all the Morrison strata in the area studied. An especially favorable area, in which the Salt Wash interval is thick and contains several thick sandstones, is situated on either side of the Utah-Colorado state line between Monticello, Utah, and Dove Creek, Colorado. The upper Morrison strata (Westwater Canyon and Brushy Basin members) have low uranium favorability. The Westwater Canyon member contains adequate sandstones but lacks known uranium deposits in the project area. The Brushy Basin member, although rated as having low potential, nevertheless does possess some attributes that make it worthy of further attention. The Recapture member does not contain sufficient well-developed sandstones or uranium deposits to merit its being classed as favorable for potential uranium-vanadium resources. (LK)

  5. To Form a Favorable Idea of Chemistry

    Science.gov (United States)

    Heikkinen, Henry W.

    2010-01-01

    "To confess the truth, Mrs. B., I am not disposed to form a very favorable idea of chemistry, nor do I expect to derive much entertainment from it." That 200-year-old statement by Caroline to Mrs. Bryan, her teacher, appeared on the first page of Jane Marcet's pioneering secondary school textbook, "Conversations on Chemistry". It was published 17…

  6. Generation Favorable Institutional Configuration Regional Business Environment

    Directory of Open Access Journals (Sweden)

    Natalia Zinovievna Solodilova

    2014-12-01

    Full Text Available This article discusses the theoretical issues of creating an enabling business environment, which is the base platform for the successful development of entrepreneurship in the regions. Provides A definition of a favorable institutional configuration of the regional business environment, which refers to forms of implementing the basic institutions and other regional institutions, taking into account existing regional system of formal and informal interaction between economic actors. States that despite the measures taken, the landscape of the Russian business community in terms of regions, remains uneven, with different indices of investment and business attractiveness, there is differentiation in business conditions in the regions with similar natural and geographical conditions and resource potential, which is primarily determined by , differences in the institutional configuration of the regional business environment and quality of interaction among the business community of the region. Hypothesis about the impossibility of creating a favorable business environment, institutional configurations at the same time in all regions of the country, as well as its limited duration. Conducted theoretical and probabilistic analysis of the parameters of creating an enabling institutional configuration of the business environment in the Russian regions. Grounded approach whereby institutional configuration of regional business environment, may be subject to management and control actions through targeted by the regional authorities can accept the specified (favorable to the business community parameters. The necessity of planning and effective management of a favorable institutional configuration of the business environment by regional authorities to increase the period of its existence.

  7. Uranium favorability of part of the Raleigh Quadrangle, North Carolina

    International Nuclear Information System (INIS)

    Part of the Raleigh, North Carolina, 10 by 20 quadrangle was evaluated to identify geologic environments favorable for uranium. Tabular sandstone deposits may occur in the Triassic basins where the Cumnock Formation interfingers with the Sanford Formation. The uranium deposits may have formed where humic and fulvic acids were expelled from lacustrine sediments to form tabular humate deposits. Later, uranium could have been concentrated and fixed when uranium-bearing ground water passed through the humate in the sandstone. Uranium may also have been precipitated in reducing environments associated with organic debris in the Pekin and Sanford Formations away from the borders of the Cumnock Formation. Analysis of water collected from wells near Corinth suggests uranium may have concentrated along fractures and faults which may be more permeable than the sediments themselves. No uranium occurrences are known in the Triassic basins, but they may have been leached during saprolitization. Water wells in quartz monzonite south of Lillington contain anomalous amounts of uranium, and the quartz monzonite contains anomalous amounts of U3O8. The quartz monzonite may contain orthomagmatic deposits, and allogenic deposits may have formed in the surrounding area. Further work in the quadrangle must include geochemical and radon analyses and studies of hydrology and paleohydrology

  8. Ensayo sobre psicoanálisis y subjetividad moderna : Discurso y sujeto de Michel Foucault: formaciones discursivas y constitución de la subjetividad moderna

    OpenAIRE

    Fedeli, Cristina Inés

    2009-01-01

    El objetivo de esta presentación es dar cuenta de las condiciones de posibilidad de la producción de un discurso sobre la subjetividad moderna. Para eso se realizó un recorrido por el pensamiento de Michel Foucault con respecto al concepto de discurso y lo que él llama la posibilidad de generación de las formaciones discursivas. El propósito es el de problematizar la cuestión de la eficacia de la palabra en la intervención clínica en nuestra época, comienzos del siglo XXI.

  9. Foraminíferos de las formaciones Jimol y Castilletes (Cuenca de Cocinetas, Alta Guajira): taxonomía y significado paleoambiental

    OpenAIRE

    Delgado Sierra, Daniel

    2015-01-01

    Se determinó la sistemática paleontológica de 39 especies de foraminíferos bentónicos y 12 especies de foraminíferos planctónicos, encontrados en las Formaciones Jimol y Castilletes (Mioceno Temprano-Medio) de la Cuenca de Cocinetas en la Alta Guajira colombiana -- A partir de estas se identificaron, por medio de un análisis de agrupamiento, 14 asociaciones de foraminíferos a través de las unidades geológicas estudiadas. La microfauna planctónica encontrada se usó para datar las unidades en e...

  10. ESTUDIO DE LÍNEA BASE DE LAS FORMACIONES CORALINAS DE YUNDIGUA Y EL MUELLE, ISLA GORGONA, PACÍFICO COLOMBIANO

    OpenAIRE

    D. Galindo-Uribe; Isaacs, P.; Acosta, A.

    2007-01-01

    Los arrecifes del Parque Nacional Natural Isla Gorgona han sido considerados los más importantes del Pacífico Oriental Tropical (POT) dada su complejidad estructural y extensión; debido a ello han sido ampliamente estudiados en Colombia.Sin embargo, la estructura de la comunidad coralina de algunas áreas aun no ha sido descrita, particularmente aquellas formaciones coralinas destinadas al uso recreativo. Sólo estudios de línea base y monitoreos permitirán definir cambios temporales causados p...

  11. Generation Favorable Institutional Configuration Regional Business Environment

    OpenAIRE

    Natalia Zinovievna Solodilova; Rustam Ilkamovich Malikov; Konstantin Yevgenevich Grishin

    2014-01-01

    This article discusses the theoretical issues of creating an enabling business environment, which is the base platform for the successful development of entrepreneurship in the regions. Provides A definition of a favorable institutional configuration of the regional business environment, which refers to forms of implementing the basic institutions and other regional institutions, taking into account existing regional system of formal and informal interaction between economic actors. Sta...

  12. Chemical modeling of formation water of the active Luna, Tabasco; Modelacion quimica de aguas de formacion del activo Luna, Tabasco

    Energy Technology Data Exchange (ETDEWEB)

    Barragan R, Rosa M; Portugal M, Enrique; Arellano G, Victor M. [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Martinez A, Ana E; Ascencio C, Fernando [Petroleos Mexicanos (Mexico)

    2001-07-01

    From the data of chemical composition of the water, the chemical equilibrium at a given temperature can be modeled for, later, obtain the saturation indexes of characteristic minerals with the intention of knowing or predict which phases can form the deposits. The Gerencia de Productividad de Pozos (GPP) of the Subdivision of Technology and Professional Development (STDP) of PEMEX, has among its objectives to promote studies tending to solve problematic that affect the wells productivity, reason why it showed interest in making a study of chemical modeling of formation waters of the Active Luna, in order to know the saturation state of the main mineral phases. This way a joint project was executed in 1997 among the GPP, the Active of Production Luna of PEMEX and the Gerencia de Geotermia of the IIE. The objectives of the project were: (a) sampling and physicochemical characterization of waters pertaining to oil wells of the Actives of Production Luna, and (b) modeling of the chemical equilibrium at well head and deposit conditions to obtain saturation indexes of characteristic minerals of hydrothermal systems, in order to predict the mineral phases that can be found in superficial and deep incrustations. [Spanish] A partir de los datos de composicion quimica del agua, pude modelarse el equilibrio quimico a una temperatura dada para, posteriormente, obtener los indices de saturacion de los minerales caracteristicos con el objeto de conocer o predecir cuales fases pueden formar los depositos. La Gerencia de Productividad de Pozos (GPP) de la Subdireccion de Tecnologia y Desarrollo Profesional (STDP) de Pemex, tiene entre sus objetivos promover estudios tendientes a resolver problematicas que impactan la productividad de los pozos, por lo que mostro interes en realizar un estudio de modelacion quimica de las aguas de formacion del Activo Luna, con el proposito de conocer el estado de saturacion de las principales fases minerales. De esta forma se realizo un proyecto

  13. Presencia de las Formaciones Piramboia y Botucatú (Triásico - Jurásico en el subsuelo oriental de la provincia de Entre Ríos The Piramboia and Botucatú formations (Triassic-Jurassic in the subsurface of eastern Entre Ríos Province

    Directory of Open Access Journals (Sweden)

    Adrián Silva Busso

    2004-03-01

    Full Text Available A partir del análisis de la información ofrecida principalmente por los pozos de prospección hidrotermal Federación 1, Concordia 1, Villa Elisa 1 y Gualeguaychú 1, perforados en el este de Entre Ríos (Mesopotamia y correlaciones con registros aflorantes en la cuenca paranense brasileña, se propone la existencia de acumulaciones representativas de las Formaciones Piramboia (fluvial; Ladiniano - Jurásico y Botucatú (principalmente eólico; Jurásico pre-Neojurásico tardío, en el subsuelo oriental de la nombrada provincia. También se indican posibles analogías y sincronismos de tales secciones del subsuelo oriental entrerriano, con las Formaciones Tacuarembó (fluvial; Ladiniano - Jurásico y Rivera (eólico; Jurásico pre- Neojurásico tardío, expuestas en Uruguay y Formación Misiones (fluvial y eólico; Ladiniano - Neojurásico temprano, asomante en Paraguay. Finalmente, se hacen referencias a posibilidades de explotación hidrotermal y almacenaje subterráneo de gas natural en Entre Ríos, Corrientes y Misiones.Data mainly from hydrothermal prospecting wells Federación 1, Concordia 1, Villa Elisa 1, and Gualeguaychú 1, and correlation with some exposed stratigraphical sections of the Brazilian Paraná Basin indicate that the subsurface succession of eastern Entre Ríos (Mesopotamia would include clastic accumulations representative of the Piramboiá Formation (fluviatile; Ladinian - Jurassic and Botucatú Formation (mainly eolian; Jurassic pre-Late neo-Jurassic. These subsurface clastic sections of eastern Entre Ríos may also represent the Tacuarembó Formation (fluviatile; Ladinian - Jurassic and Rivera Formation (eolian; Jurassic, pre-Late neo-Jurassic of Uruguay, and Misiones Formation (fluviatile and eolian; Ladinian - Early neo-Jurassic of Paraguay. The potential for hydrothermal exploitation and subterranean storage of natural gas in Entre Ríos, Corrientes, and Misiones is discussed.

  14. Preliminary Study of Favourable Formations for CO{sub 2} Subsurface Storage in Spain; Estudio Preliminar de las Formaciones Favorables para el Almacenamiento Subterraneo de CO{sub 2} en Espana

    Energy Technology Data Exchange (ETDEWEB)

    Zapatero, M. A.; Reyes, J. L.; Martinez, R.; Suarez, I.; Arenillas, A.; Perucha, M. A.

    2009-10-12

    This report is a synthesis of the possibilities of CO{sub 2} storage in the Spanish subsurface. Compilation and analysis of geological information has been carried out, looking at surface and subsurface, in order to make a pre-selection of potential favourable units for CO{sub 2} storage, taking in account that each of this storages needs a confining formation to seal the storage. Before the storage selection, a general description of the great geological units of the Iberian Peninsula is done. Afterwards, borehole logging from petroleum exploration is analysed in these units, formations and areas of interest. The aim is to finally obtain a description of selected units and their possibilities of CO{sub 2} storage. (Author) 17 refs.

  15. Uranium favorability of the San Rafael Swell area, east-central Utah

    International Nuclear Information System (INIS)

    The San Rafael Swell project area in east-central Utah is approximately 3,000 sq mi and includes the San Rafael Swell anticline and the northern part of the Waterpocket Fold monocline at Capitol Reef. Rocks in the area are predominantly sedimentary rocks of Pennsylvanian through Cretaceous age. Important deposits of uranium in the project area are restricted to two formations, the Chinle (Triassic) and Morrison (Jurassic) Formations. A third formation, the White Rim Sandstone (Permian), was also studied because of reported exploration activity. The White Rim Sandstone is considered generally unfavorable on the basis of lithologic characteristics, distance from a possible source of uranium, lack of apparent mineralization, and the scarcity of anomalies on gamma-ray logs or in rock, water, and stream-sediment samples. The lower Chinle from the Moss Back Member down to the base of the formation is favorable because it is a known producer. New areas for exploration are all subsurface. Both Salt Wash and Brushy Basin Members of the Morrison Formation are favorable. The Salt Wash Member is favorable because it is a known producer. The Brushy Basin Member is favorable as a low-grade resource

  16. Innovation in the processes of formation and training of nuclear professionals; La innovacion en los procesos de formacion y entranamiento de los profesionales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Martinez, F. J.; Lambistos Agustin, A.

    2015-07-01

    Innovation is the intoduction of new products and services, new processes, new sources of supply and changes in industrial organization, and continuous customer, consumer or user oriented (J. A. Schumpeter). According to this idea, three mental restrictions usually apply to the innovative break: not only are new products, not only are technological developments, not only are revolutionary ideas so also. From the innovative tradition of Tecnatom Formacion Nuclear materailized in examples like the SGI or Human Factors simulators, in recent years has made considerable progress in the function with innovative solutions to improve the results of nuclear power plants, made available to our customers, as significant as the Training Programs for Shift Supervisors, the OJT/TPE processes, seminars Diagnostic Techniques, EDMG Simulator or ROI and ROIF projects. (Author)

  17. ESTUDIO DE LÍNEA BASE DE LAS FORMACIONES CORALINAS DE YUNDIGUA Y EL MUELLE, ISLA GORGONA, PACÍFICO COLOMBIANO

    Directory of Open Access Journals (Sweden)

    D. Galindo-Uribe

    2007-06-01

    Full Text Available Los arrecifes del Parque Nacional Natural Isla Gorgona han sido considerados los más importantes del Pacífico Oriental Tropical (POT dada su complejidad estructural y extensión; debido a ello han sido ampliamente estudiados en Colombia.Sin embargo, la estructura de la comunidad coralina de algunas áreas aun no ha sido descrita, particularmente aquellas formaciones coralinas destinadas al uso recreativo. Sólo estudios de línea base y monitoreos permitirán definir cambios temporales causados por las actividades antrópicas y la capacidad de carga soportada por los corales en Gorgona. Por ello, la estructura de la comunidad de escleractíneos se estimó en términos de composición, cobertura, diversidad (alfa y beta y distribución espacial tanto en Yundigua (bajo uso reciente no extractivo como en El Muelle (altamente disturbada en el pasado-uso extractivo, y ahora bajo protección. Yundigua, descrito aquí por primera vez para Gorgona, presenta un tipo de arrecife denominado comunidad coralina, siendo dominado por especies masivas y ramificadas que colonizan cantos rodados en un fondo predominantemente arenoso, lo que limita su distribución espacial. Esta comunidad es altamente heterogénea en el espacio en términos de composición y cobertura. El Muelle, arrecife zonificado de tipo franjeante, es dominado por especies ramificadas del género Pocillopora, principalmente en la cresta arrecifal. La cobertura relativa de coral vivo no fué significativamente diferente entre las dos formaciones; no obstante, la geomorfología arrecifal si lo fué, por la forma de crecimiento de las especies. La comunidad coralina de Yundigua presentó la mayor riqueza (6 especies, diversidad y uniformidad respecto al arrecife de El Muelle (3 especies y la prueba t de Shannon corroboró este resultado.La baja similaridad estructural entre las dos formaciones coralinas (50%, Bray Curtis, respalda la alta complementariedad taxonómica encontrada (71% entre las

  18. Analysis on the hydrogeological condition and uranium mineralization prospect in Santanghu basin, Xinjiang

    International Nuclear Information System (INIS)

    Santanghu basin is an infiltration depression basin with forward direction hydrogeological and hydrogeochemical zonation. The basin has a well developed aquifer and favorable mud-sand-mud pattern and abundant uranium source. The distribution pattern of uranium in the ground water is favorable for the precipitation and enrichment of uranium in transitional part of redox zone. (authors)

  19. 19 CFR 200.735-105 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Gifts, entertainment, and favors. 200.735-105...-105 Gifts, entertainment, and favors. (a) Except as provided in paragraph (b) of this section, no employee may solicit or accept, directly or indirectly, any gift, gratuity, favor, entertainment, loan,...

  20. 11 CFR 7.20 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-01-01

    ... of Special Commission Employees § 7.20 Gifts, entertainment, and favors. Except as provided at 11 CFR... 11 Federal Elections 1 2010-01-01 2010-01-01 false Gifts, entertainment, and favors. 7.20 Section... a gift, gratuity, loan, entertainment, or favor for himself or herself, or for another...

  1. 25 CFR 700.519 - Gifts, entertainment and favors.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Gifts, entertainment and favors. 700.519 Section 700.519... Employee Responsibility and Conduct § 700.519 Gifts, entertainment and favors. (a) Acceptance of gratuities, including gifts, entertainment and favors, (no matter how innocently tendered or received) from those...

  2. 22 CFR 1203.735-305 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Gifts, entertainment, and favors. 1203.735-305....735-305 Gifts, entertainment, and favors. (a) Except as provided in paragraph (b) of this section, a..., gratuity, loan, entertainment, or favor for the employee or another person, particularly one with whom...

  3. Trace Element Characteristics of Eocene Jijuntun Formation and the Favorable Metallogenic Conditions of Oil Shale in Fushun Basin%抚顺盆地始新统计军屯组微量元素特征及油页岩的有利成矿条件

    Institute of Scientific and Technical Information of China (English)

    胡晓峰; 刘招君; 柳蓉; 刘冬青; 张明明; 许圣传; 孟庆涛

    2012-01-01

    通过剖面上样品的无机地球化学元素分析,对始新统计军屯组微量元素特征进行了研究,并据此探讨了计军屯组油页岩的有利成矿条件.计军屯组贫矿段和富矿段Sr/Cu、Rb/Sr、Sr/Ba、B/Ga的平均值分别为2.30、0.63、0.20、1.07和3.41、0.43、0.34、1.50,结合元素Rb、Sr、Cu、Ba、Ga、B的质量分数,揭示了计军屯组形成于温暖湿润气候和淡水沉积环境:西露天组Sr/Cu、Rb/Sr、Sr/Ba、B/Ga的平均值分别为24.63、0.14、1.25、3.90,结合元素Rb、Sr、Cu、Ba、Ga、B的质量分数,揭示了西露天组形成于干旱炎热气候和半成水一成水环境.古气候和古盐度的元素地球化学参数Sr/Cu、Rb/Sr和Sr/Ba的相关关系以及西露天组碳酸盐岩碳、氧同位素的相关关系,指示了研究区计军屯组富矿段和西露天组沉积时古气候是湖泊古盐度的主要控制因素,并且古湖泊较为封闭.研究区计军屯组高品质油页岩形成于温暖湿润气候和淡水沉积环境.温暖湿润气候和封闭型古湖泊可能是形成研究区高品位油页岩的有利条件.%Based on the field geological profile and inorganic geochemical elemental analysis of samples, trace element characteristics of Eocene Jijuntun Formation have been studied and favorable oil shale metallogenic conditions have been discussed. The average values Sr/Cu, Rb/Sr, Sr/Ba, B/Ga in poor ore and rich ore seg- ments of Jijuntun Formation are 2. 30, 0. 63, 0. 20, 1. 07 and 3.41, 0. 43, 0. 34, 1. 50 separately. The contents of Rb,Sr,Cu,Ba,Ga,B and those ratios indicate that in study aera Jijuntun Formation formed in warm, humid climatic conditions and fresh water environment. The average values of Sr/Cu, Rb/Sr, Sr/Ba and B/G are 24.63, 0. 14, 1.25 and 3.90 respectively, and these ratios and the contents of Rb,Sr,Cu,Ba,Ga,B indicate Xiloutian Formation formed in dry, hot climatic conditions and simisaline-saline water environment. Correlation between Sr/Cu, Rb

  4. News Palynology data of the basal section of Formacion San Gregorio located in Paso de las Bochas (I lower permian north basin, Uruguay

    International Nuclear Information System (INIS)

    Samples from outcrops and concretions of the locality of Paso de las Bochas on the Negro River, provided new palynologycal data to the basal section of the San Gregorio Formation. At least 10 new ta xa are added for San Gregorio concretions, and some of the cited palynomorphs are mentioned for the first time for Uruguay (Rattiganispora minor, Waltzispora pol ita). Moreover, some of the found ta xa have been mentioned for glacial deposits related to the Carboniferous-Permian boundary in other Gondwana regions (p.e. Psomospora detect a, Waltzispora pol ita). The preliminary results reached here allow to admit the hypothesis of the existence of carboniferous dee posits on the Uruguayan territory whose were eroded or not yet recognized. Keywords: San Gregorio Formation, Carboniferous

  5. Educational software tool for protection system engineers: distance relay; Herramienta educativa para la formacion de ingenieros en protecciones electricas: relevador de distancia

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo-Guajardo, L.A.; Conde-Enriquez, A. [Universidad Autonoma de Nuevo Leon, Nuevo Leon (Mexico)]. E-mail: luistrujillo84@gmail.com; con_de@yahoo.com

    2012-04-15

    In this article, a graphical software tool is presented; this tool is based on the education of protection system engineers. The theoretical fundaments used for the design of operation characteristics of distance relays and their algorithms are presented. The software allows the evaluation and analysis of real time events or simulated ones of every stage of design of the distance relay. Some example cases are presented to illustrate the activities that could be done with the graphical software tool developed. [Spanish] En este articulo se presenta una herramienta computacional grafica para apoyar la formacion de ingenieros en protecciones electricas. Los fundamentos teoricos para el diseno de caracteristicas de operacion de relevadores de distancia, asi como las rutinas de programacion de un relevador de distancia son presentados. La herramienta desarrollada permite la evaluacion de las etapas de diseno de relevadores y el analisis de la operacion ante eventos reales o simulados. Se presentan algunos casos de ejemplo para ilustrar las actividades didacticas que son posibles de realizar con la herramienta presentada.

  6. 11 CFR 7.8 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-01-01

    ... Constitution and in section 7342 of title 5, United States Code. (e) Neither this section nor 11 CFR 7.7... 11 Federal Elections 1 2010-01-01 2010-01-01 false Gifts, entertainment, and favors. 7.8 Section 7... Employees or Commissioners § 7.8 Gifts, entertainment, and favors. (a) A Commissioner or employee of...

  7. 36 CFR 905.735-202 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-07-01

    ..., entertainment, and favors. Pursuant to paragraph (b) of 5 CFR 735.202, the following exceptions to the... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Gifts, entertainment, and favors. 905.735-202 Section 905.735-202 Parks, Forests, and Public Property PENNSYLVANIA...

  8. 18 CFR 706.202 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Gifts, entertainment..., entertainment, and favors. (a) Except as provided in paragraphs (b) and (c) of this section, an employee shall not solicit or accept, directly or indirectly, any gift, gratuity, favor, entertainment, loan, or...

  9. 22 CFR 1203.735-202 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Gifts, entertainment, and favors. 1203.735-202..., entertainment, and favors. (a) Acceptance prohibited. Except as provided in paragraphs (b), (c), and (d) of this..., entertainment, loan, or any other thing of monetary value, from a person who: (1) Has, or is seeking to...

  10. 18 CFR 706.303 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Gifts, entertainment....303 Gifts, entertainment, and favors. (a) Except as provided in paragraph (b) of this section a..., entertainment, or favor for himself or another person, particularly one with whom he has family, business,...

  11. Why Koreans are More Likely to Favor "Apology," While Americans are More Likely to Favor "Thank You"

    Science.gov (United States)

    Lee, Hye Eun; Park, Hee Sun

    2011-01-01

    Two studies investigated whether apologies or thanks are preferred in asking favors in the United States and Korea, and how this relates to perceptions of reduction in positive and negative face threats. In the first study (n = 224), participants composed an e-mail message where a favor was asked. In the second (n = 807), participants completed…

  12. Social Capital and Social Quilts: Network Patterns of Favor Exchange

    OpenAIRE

    Jackson, Matthew O.; Tomas Rodriguez-Barraquer; Xu Tan

    2012-01-01

    We examine the informal exchange of favors in societies such that any two individuals interact too infrequently to sustain exchange, but such that the social pressure of the possible loss of multiple relationships can sustain exchange. Patterns of exchange that are locally enforceable and renegotiation-proof necessitate that all links are "supported": any two individuals exchanging favors have a common friend. In symmetric settings, such robust networks are "social quilts": tree-like unions o...

  13. Presencia de las Formaciones Piramboia y Botucatú (Triásico - Jurásico en el subsuelo oriental de la provincia de Entre Ríos

    Directory of Open Access Journals (Sweden)

    Adrián Silva Busso

    2004-03-01

    Full Text Available A partir del análisis de la información ofrecida principalmente por los pozos de prospección hidrotermal Federación 1, Concordia 1, Villa Elisa 1 y Gualeguaychú 1, perforados en el este de Entre Ríos (Mesopotamia y correlaciones con registros aflorantes en la cuenca paranense brasileña, se propone la existencia de acumulaciones representativas de las Formaciones Piramboia (fluvial; Ladiniano - Jurásico y Botucatú (principalmente eólico; Jurásico pre-Neojurásico tardío, en el subsuelo oriental de la nombrada provincia. También se indican posibles analogías y sincronismos de tales secciones del subsuelo oriental entrerriano, con las Formaciones Tacuarembó (fluvial; Ladiniano - Jurásico y Rivera (eólico; Jurásico pre- Neojurásico tardío, expuestas en Uruguay y Formación Misiones (fluvial y eólico; Ladiniano - Neojurásico temprano, asomante en Paraguay. Finalmente, se hacen referencias a posibilidades de explotación hidrotermal y almacenaje subterráneo de gas natural en Entre Ríos, Corrientes y Misiones.

  14. The most-favored nation rule in club enlargement negotiation

    OpenAIRE

    Edwin L.-C. Lai

    2008-01-01

    We study the effects of the Most-Favored Nation rule in an applicant's negotiation to join a club. When the applicant has to carry out a series of bilateral bargains with the existing members, we find that there are two effects of the MFN rule, viz. the hardened bargainer effect and the free-rider effect. The former effect tends to favor the applicant, while the latter effect tends to hurt the applicant. We find that the free-rider effect is stronger the more asymmetric are the members. The h...

  15. Favorable Policy for Foreign Investors in Dagang Oilfield

    Institute of Scientific and Technical Information of China (English)

    Liu Mingfa

    1995-01-01

    @@ Apart from series kinds of good products, advanced techniques, convenient communications and electric power and water supply in Dagand Oilfield, foreign investors who have investment in New Industrial Area of Dagang Oilfield will enjoy the same favourable policies as Tianjin Economic Develoment Zone. Main favorable policies are follows:

  16. Fundación del Centro de Enseñanza de Lenguas Extranjeras de la Universidad Nacional Autónoma de México. Formaciones intermediarias

    Directory of Open Access Journals (Sweden)

    Sonia Bufi Zanon

    2014-01-01

    Full Text Available Este texto expone algunos de los temas nucleares, encontrados en fuentes documentales y a través de entrevistas a profundidad a actores principales de la fundación de un centro de enseñanza de Lenguas Extranjeras en la Universi dad Nacional Autónoma de México a finales de los años 70. Presenta los hallazgos y el análisis de los datos contenidos en uno de los capítulos de la tesis doctoral en Investigaciones Educativas, bajo la dirección del Doctor Eduardo Remedi: “Ecos de Babel. Proceso de institucionalización y construcción identitaria en el Centro de Enseñanza de Lenguas Extranjeras de la UNAM”, sostenida en julio de 2008. La presentación del caso estudiado desde una perspectiva etnográfica, que corresponde al periodo fundacional de • Doctora en Ciencias, en la especialidad de Investigaciones Educativas por parte del Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional de México. Labora en el Centro de Enseñanza de Lenguas Extranjeras de la Universidad Nacional Autónoma de México. soniabufi@gmail.com dicho establecimiento educativo, contempla: una introduc - ción al marco teórico utilizado que se basa en las propuestas psicosocioanalíticas de René Kaës, psicoanalista y profesor de psicología y psicopatología clínica en la Universidad de Lyon 2; los datos más relevantes de la historia fundacional del caso estudiado y algunas reflexiones finales donde se pretende comprender este proceso de institucionalización a la luz de las teorías expuestas. Se centra en particular en lo que René Kaës llamó, en su afán por “comprender la psicología del grupo en sus relaciones con la de los sujetos que lo integran, así como las características de los elementos que se constituyen como los operadores de esas relaciones” (Segoviano, 2010, “formaciones y procesos intermediarios”.

  17. Design integration of favorable geometry, structural support and containment

    International Nuclear Information System (INIS)

    In designs for fissile processes at Savannah River site, different approaches have been used to provide engineered margins of safety for criticality with containment and seismic resistance as additional requirements. These requirements are frequently at odds in engineered systems. This paper proposes a plan to take advantage of vessels with favorable geometry to provide seismic resistance and to support a glovebox for containment. Thin slab tanks, small diameter pencil tanks, annular tanks, and other novel designs have been used for criticality safety. The requirement for DBE seismic resistance and rigid control of dimensions leads the designer to consider annular tanks for meeting these requirements. The high strength of annular tanks may logically be used to support secondary containment. Hands-on access to all instruments, piping etc. within containment can be provided through gloveports, thus a specialized glovebox. This paper examines the advantages of using an annular tank design to provide favorable geometry, structural support and containment

  18. HOW MUCH FAVORABLE SELECTION IS LEFT IN MEDICARE ADVANTAGE?

    OpenAIRE

    Newhouse, Joseph P.; Mary Price; J. Michael McWilliams; John Hsu; Thomas McGuire

    2015-01-01

    The health economics literature contains two models of selection, one with endogenous plan characteristics to attract good risks and one with fixed plan characteristics; neither model contains a regulator. Medicare Advantage, a principal example of selection in the literature, is, however, subject to anti-selection regulations. Because selection causes economic inefficiency and because the historically favorable selection into Medicare Advantage plans increased government cost, the effectiven...

  19. Coevolution of robustness, epistasis, and recombination favors asexual reproduction

    OpenAIRE

    MacCarthy, Thomas; Bergman, Aviv

    2007-01-01

    The prevalence of sexual reproduction remains one of the most perplexing phenomena in evolutionary biology. The deterministic mutation hypothesis postulates that sexual reproduction will be advantageous under synergistic epistasis, a condition in which mutations cause a greater reduction in fitness when combined than would be expected from their individual effects. The inverse condition, antagonistic epistasis, correspondingly is predicted to favor asexual reproduction. To assess this hypothe...

  20. Children in Foster Care and the Development of Favorable Outcomes

    OpenAIRE

    Healey, Cynthia V.; Fisher, Philip A.

    2011-01-01

    Young foster children have invariably faced a variety of risks that are strongly linked to long-term deficits in functioning across multiple developmental domains. Despite these risks, however, some children demonstrate more favorable outcomes and exhibit adaptation and the development of assets. In the present study, the relationship of early childhood factors (e.g., maltreatment history, placement history, parenting practices, environmental stress, developmental status, and attachment behav...

  1. Menor valor: ¿oferta más favorable?

    Directory of Open Access Journals (Sweden)

    Iván Alirio Ramírez Rusinque

    2014-07-01

    Full Text Available La más importante transformación establecida por la Ley 1150 de 2007 en la contratación estatal radicó en la determinación del menor valor como la oferta más favorable para las entidades estatales, cuando se trate de la adquisición o suministro de bienes y servicios de características técnicas uniformes y de común utilización. Por ello, reviste de gran importancia realizar un análisis desde el punto de vista jurídico y normativo, que permita establecer si la mutación sufrida al concepto de oferta más favorable trajo consigo los fines perseguidos por la reforma, o en su defecto fue perjudicial la solución, al afectar el deber de selección objetiva, los principios de la contratación estatal de igualdad, eficacia, transparencia, planeación y equilibrio financiero del contrato y el principio constitucional de la libre competencia. Para de esta forma establecer si el modelo del menor valor como criterio de la oferta más favorable resulta eficiente jurídicamente en el campo de la contratación estatal, y si las reglas establecidas en la actualidad permiten el desarrollo armónico del sistema establecido por la Ley 1150 de 2007.

  2. Vinna Basin

    Czech Academy of Sciences Publication Activity Database

    Honěk, J.; Franců, J.; Mikuláš, Radek; Pešek, J.; Sýkorová, Ivana; Tomanová-Petrová, P.

    Prague: Czech Geological Survey, 2014, s. 223-241 ISBN 978-80-7075-862-5 R&D Projects: GA ČR GA105/06/0653 Institutional support: RVO:67985891 ; RVO:67985831 Keywords : Tertiary basins * Czech Republic * Cenomanian and Tertiary lignite * geology * stratigraphy Subject RIV: DB - Geology ; Mineralogy

  3. Caracterización geoquímica de la esméctica en varias formaciones arcillosas de los flyschs del Campo de Gibraltar (Cádiz, España

    Directory of Open Access Journals (Sweden)

    Esteras Martín, M.

    1993-12-01

    Full Text Available The «Jimena clays», «basal series of Aljibe» and «blocky clays» formations are compared from the mineralogical and geochemical analysis. The mineralogy of clays is very similar in all the sequences analyzed and consists of quartz, smectite, illite and kaolinite. Smaller amounts of feldspar, gypsum and chlorite are locally presento In the 2-20 μm and Se comparan desde un punto de vista mineralógico y geoquímico las formaciones definidas como «arcillas de Jimena», «sucesión basal del Aljibe» y «arcillas con bloques». Su mineralogía resulta muy similar: cuarzo, esmectita, ilita y caolinita, junto con pequeñas proporciones de feldespato, yeso y clorita. En las fracciones 2-20 µm y < 2 μm la esmectita es el mineral más abundante. La semejanza mineralógica se pone también de manifiesto en la composición química de estos materiales. La composición de las esmectitas corresponde a montmorillonita y sugiere un origen detrítico para las mismas. El contenido en diversos elementos traza indica que estos materiales son el producto de la meteorización de rocas magmáticas ácidas junto con rocas sedimentarias antiguas. La homogeneidad de las secuencias analizadas indica, asimismo, una homología de todas las formaciones y una gran uniformidad en los aportes durante el intervalo Cretácico-Eoceno, época a la que se atribuye su depósito.

  4. Comparison between control factors of high quality continental reservoirs in Bohai Bay basin and Ordos basin

    Institute of Scientific and Technical Information of China (English)

    Junmao ZHENG; Jun YOU; Dongbo HE

    2008-01-01

    Bohai Bay basin,a typical extensional rift basin,and Ordos basin,an intra-craton down-warped basin,represent two important basin types in China.Because of their respective features,the main control factors for their high quality reservoirs are different.In Bohai Bay basin,the sandbody shows great variety in types and severely separated distribution and its high quality reservoirs are mostly controlled by the vertical secondary pore and vertical abnormal pressure.On the other hand,the sandbody in Ordos basin features a relative lack of variety,good continuity,indistinct vertical zone,and its reservoirs are mainly controlled bY the diagenetic differentiation caused by different sedimentation inside the sandbody.Therefore,in the Bohai Bay basin,the exploration should be based on the analysis of sedimentary facies and the favorable diagenefic zones and formations.The focus in Ordos basin,however,should be put on the relatively high permeability sandstones in a generally low permeable sandstone background.

  5. High nevus counts confer a favorable prognosis in melanoma patients

    OpenAIRE

    Ribero, Simone; Davies, John R; Requena, Celia; Carrera, Cristina; Glass, Daniel; Rull, Ramon; Vidal-Sicart, Sergi; Vilalta, Antonio; Alos, Lucia; Soriano, Virtudes; Quaglino, Pietro; Traves, Victor; Newton-Bishop, Julia A; Nagore, Eduardo; Malvehy, Josep

    2015-01-01

    A high number of nevi is the most significant phenotypic risk factor for melanoma and is in part genetically determined. The number of nevi decreases from middle age onward but this senescence can be delayed in patients with melanoma. We investigated the effects of nevus number count on sentinel node status and melanoma survival in a large cohort of melanoma cases. Out of 2,184 melanoma cases, 684 (31.3%) had a high nevus count (>50). High nevus counts were associated with favorable progno...

  6. Potato: A Favorable Crop for Plant Molecular Farming

    Institute of Scientific and Technical Information of China (English)

    Sunil Kumar G B; Ganapathi T R; Bapat V A

    2006-01-01

    Potato is one of the important food crops with a high yield potential and nutritional value. It has been used extensively for molecular farming to produce vaccines, antibodies and industrial enzymes. It has several desirable attributes as a favorable crop for the production of recombinant proteins. Potato tubers were employed for bulk production of recombinant antibodies. Vaccine production in potato has progressed to human clinical trials. Human milk proteins were successfully expressed in potato tubers. Potato hairy roots offer as another attractive system for the production of useful recombinant proteins both as intra cellular and secreted forms. This review describes the use of potato as a prospective host for plant molecular farming.

  7. Catalytically favorable surface patterns in Pt-Au nanoclusters

    KAUST Repository

    Mokkath, Junais Habeeb

    2013-01-01

    Motivated by recent experimental demonstrations of novel PtAu nanoparticles with highly enhanced catalytic properties, we present a systematic theoretical study that explores principal catalytic indicators as a function of the particle size and composition. We find that Pt electronic states in the vicinity of the Fermi level combined with a modified electron distribution in the nanoparticle due to Pt-to-Au charge transfer are the origin of the outstanding catalytic properties. From our model we deduce the catalytically favorable surface patterns that induce ensemble and ligand effects. © The Royal Society of Chemistry 2013.

  8. The Uneasy Case for Favoring Long-Term Shareholders

    OpenAIRE

    Jesse M. Fried

    2015-01-01

    This paper challenges a persistent and pervasive view in corporate law and corporate governance: that a firm’s managers should favor long-term shareholders over short-term shareholders, and maximize long-term shareholders’ returns rather than the short-term stock price. Underlying this view is a strongly-held intuition that taking steps to increase long-term shareholder returns will generate a larger economic pie over time. But this intuition, I show, is flawed. Long-term shareholders, like s...

  9. Observations favor the crossing of phantom divide lines

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Using three different parameterized dark energy models, we reconstruct the properties of dark energy from the latest 397 Sne Ia, CMB and BAO with the present matter density, Ωm0, given prior. We find that, when Ωm0 is not small, for example, Ωm0 = 0.28 or 0.32, an evolving dark energy with a crossing of phantom divide line is favored and this conclusion seems to be model independent. We also find that the evolving properties of dark energy become more and more evident with the increase of Ωm0 given prior.

  10. Are priors responsible for cosmology favoring additional neutrino species?

    CERN Document Server

    Gonzalez-Morales, Alma X; Sherwin, Blake D; Verde, Licia

    2011-01-01

    It has been suggested that both recent cosmological data and the results of flavor oscillation experiments (MiniBooNE and LSND) lend support to the existence of low-mass sterile neutrinos. The cosmological data appear to weakly favor additional forms of radiation in the Universe, beyond photons and three standard neutrino families. We reconsider the cosmological evidence by making the resulting confidence intervals on the additional effective neutrino species as prior-independent as possible. We find that, once the prior-dependence is removed, the latest cosmological data show no evidence for deviations from the standard number of neutrino species.

  11. Structural Characteristics and Evolution of Jurassic Basins in the East of Middle Qilian Block

    Institute of Scientific and Technical Information of China (English)

    郑孟林; 李明杰; 曹春潮; 张勇军; 徐世陆

    2003-01-01

    Structural characteristics of the Jurassic basins of Xining, Minhe, and Xiji in the east of middle Qilian were researched based on the data obtained by gravitational, magnetic, and seismic methods. The result shows that each of these three basins is an independent structural unit with a NW strike and being separated by upheavals. Two groups of faults with NW and NE directions are developed in the basin, which controls the formation and evolution of the (Jurassic basins). The NW faults are the main ones while the NE faults are the secondary for controlling the sedimentation. Of the three basins, the Minhe basin is the favorable prospecting area.

  12. Muestreo en transecto de formaciones vegetales de fanerófitos y caméfitos (I: fundamentos metodológicos

    Directory of Open Access Journals (Sweden)

    Cámara Artigas, Rafael

    2013-06-01

    Full Text Available This study presents a quantitative geobotanical method of inventory for homogeneous vegetation formations (phanerophytes and chamaephytes (method MIFC. The technique used is an inventory of vegetation (phanerophytes and chamaephytes in transects of 50x2 m. Resulting in plots of 0.1 ha., the attributes and the relative position of the vegetation along the transect. For the study of vegetation, the analytical basis method considers 10 sample plots. The results provide data on biodiversity (Shannon, Simpson, mesological factors and the ecological Importance Value Index (IVI. Finally, the MIFC method develops a specific structural graph, consisting of the Wealth-Structure-Coverage Ecodynamics Diagram (EDWSC for the vertical structure and a Bubble Diagram (DB for the horizontal structure.Se presenta un Método geobotánico cuantitativo de Inventario de formaciones vegetales homogéneas (Fanerófitos y Caméfitos (método MIFC. La técnica utilizada es un inventario de vegetación (fanerófitos y caméfitos en transectos lineales de 50x2 m, dando lugar a parcelas de 0,1 has, atributos y posición relativa de la vegetación a lo largo del transecto. El método considera como base analítica del estudio de la vegetación, 10 parcelas de muestreo. Los resultados proporcionan datos sobre la biodiversidad (Shannon, Simpson, factores mesológicos e índice de valor de importancia (IVI ecológica. Finalmente el método MIFC desarrolla una representación gráfica estructural específica, consistente en el «Diagrama Ecodinámico de Riqueza-Estructura-Cobertura » (DEREC para la vertical y en un «Diagrama de Burbujas» (DB para la horizontal. [fr] Nous présentons ici une méthode géobotanique quantitative d’Inventaire de formations végétales homogènes (Phanérophytes et Chamaephytes (méthode MIFC. La technique utilisée est un inventaire de la végétation (phanérophytes et chamaephytes des transects linéaires de 50x2 m, donnant lieu à des

  13. Reticulate evolution is favored in influenza niche switching.

    Science.gov (United States)

    Ma, Eric J; Hill, Nichola J; Zabilansky, Justin; Yuan, Kyle; Runstadler, Jonathan A

    2016-05-10

    Reticulate evolution is thought to accelerate the process of evolution beyond simple genetic drift and selection, helping to rapidly generate novel hybrids with combinations of adaptive traits. However, the long-standing dogma that reticulate evolutionary processes are likewise advantageous for switching ecological niches, as in microbial pathogen host switch events, has not been explicitly tested. We use data from the influenza genome sequencing project and a phylogenetic heuristic approach to show that reassortment, a reticulate evolutionary mechanism, predominates over mutational drift in transmission between different host species. Moreover, as host evolutionary distance increases, reassortment is increasingly favored. We conclude that the greater the quantitative difference between ecological niches, the greater the importance of reticulate evolutionary processes in overcoming niche barriers. PMID:27114508

  14. Favorable Outcome in Open Globe Injuries with Low OTS Score

    Institute of Scientific and Technical Information of China (English)

    Cillino Giovanni; Ferraro Lucia; Casuccio Alessandra; Cillino Salvatore

    2014-01-01

    Purpose:.Open globe eye injuries can have profound social and economic consequences. Here, we describe two cases of war and outdoor activity open globe eye injury where, despite a low OTS score,.current microsurgical technology allowed for a favorable outcome.Case report 1: A 33-year-old Libyan soldier had been treated for an open-globe grenade blast trauma to his left eye, which showed light perception and OTS score 2..He had undergone a lensectomy and PPV with silicone oil tamponade. Surgical treatment included scleral buckling,.cornea trephination, tem-porary Eckardt keratoprosthesis, PPV revision, intraocular lens (IOL) implantation, and corneal grafting. Six months later, his VA was improved to 20 / 70.Case report 2:.A 35-year-old man presented with a corneal laceration in his left eye from a meat skewer,.with marked hypotony and LP..After primary corneal wound closure,.B-scan ultrasonography revealed massive vitreous hemorrhage (OTS score 2). The patient underwent open cataract extraction with IOL implantation, 23 gauge PPV, laser photocoagulation of the retinochoroidal laceration, and a gas tamponade. After three weeks,.the patient underwent a 2nd 23G PPV due to a fibrinous reaction. Six month later, the patients exhibited 20 /25 VA.Conclusion:.These cases confirm that even for patients with a low OTS and poor visual prognosis,.an up-to-date surgery protocol may achieve visual results adequate for leading an autonomous daily life. (Eye Science 2014; 29:170-173)

  15. Ecological conditions favoring budding in colonial organisms under environmental disturbance.

    Directory of Open Access Journals (Sweden)

    Mayuko Nakamaru

    Full Text Available Dispersal is a topic of great interest in ecology. Many organisms adopt one of two distinct dispersal tactics at reproduction: the production of small offspring that can disperse over long distances (such as seeds and spawned eggs, or budding. The latter is observed in some colonial organisms, such as clonal plants, corals and ants, in which (superorganisms split their body into components of relatively large size that disperse to a short distance. Contrary to the common dispersal viewpoint, short-dispersal colonial organisms often flourish even in environments with frequent disturbances. In this paper, we investigate the conditions that favor budding over long-distance dispersal of small offspring, focusing on the life history of the colony growth and the colony division ratio. These conditions are the relatively high mortality of very small colonies, logistic growth, the ability of dispersers to peacefully seek and settle unoccupied spaces, and small spatial scale of environmental disturbance. If these conditions hold, budding is advantageous even when environmental disturbance is frequent. These results suggest that the demography or life history of the colony underlies the behaviors of the colonial organisms.

  16. Competition favors elk over beaver in a riparian willow ecosystem

    Science.gov (United States)

    Baker, B.W.; Peinetti, H.R.; Coughenour, M.C.; Johnson, T.L.

    2012-01-01

    Beaver (Castor spp.) conservation requires an understanding of their complex interactions with competing herbivores. Simulation modeling offers a controlled environment to examine long-term dynamics in ecosystems driven by uncontrollable variables. We used a new version of the SAVANNA ecosystem model to investigate beaver (C. Canadensis) and elk (Cervus elapses) competition for willow (Salix spp.). We initialized the model with field data from Rocky Mountain National Park, Colorado, USA, to simulate a 4-ha riparian ecosystem containing beaver, elk, and willow. We found beaver persisted indefinitely when elk density was or = 30 elk km_2. The loss of tall willow preceded rapid beaver declines, thus willow condition may predict beaver population trajectory in natural environments. Beaver were able to persist with slightly higher elk densities if beaver alternated their use of foraging sites in a rest-rotation pattern rather than maintained continuous use. Thus, we found asymmetrical competition for willow strongly favored elk over beaver in a simulated montane ecosystem. Finally, we discuss application of the SAVANNA model and mechanisms of competition relative to beaver persistence as metapopulations, ecological resistance and alternative state models, and ecosystem regulation.

  17. Patients with Spinal Cord Injuries Favor Administration of Methylprednisolone

    Science.gov (United States)

    Bowers, Christian A.; Kundu, Bornali; Rosenbluth, Jeffrey; Hawryluk, Gregory W. J.

    2016-01-01

    Methylprednisolone sodium succinate (MPSS) for treatment of acute spinal cord injury (SCI) has been associated with both benefits and adverse events. MPSS administration was the standard of care for acute SCI until recently when its use has become controversial. Patients with SCI have had little input in the debate, thus we sought to learn their opinions regarding administration of MPSS. A summary of the published literature to date on MPSS use for acute SCI was created and adjudicated by 28 SCI experts. This summary was then emailed to 384 chronic SCI patients along with a survey that interrogated the patients’ neurological deficits, communication with physicians and their views on MPSS administration. 77 out of 384 patients completed the survey. 28 respondents indicated being able to speak early after injury and of these 24 reported arriving at the hospital within 8 hours of injury. One recalled a physician speaking to them about MPSS and one patient reported choosing whether or not to receive MPSS. 59.4% felt that the small neurological benefits associated with MPSS were ‘very important’ to them (p<0.0001). Patients had ‘little concern’ for potential side-effects of MPSS (p = 0.001). Only 1.4% felt that MPSS should not be given to SCI patients regardless of degree of injury (p<0.0001). This is the first study to report SCI patients’ preferences regarding MPSS treatment for acute SCI. Patients favor the administration of MPSS for acute SCI, however few had input into whether or not it was administered. Conscious patients should be given greater opportunity to decide their treatment. These results also provide some guidance regarding MPSS administration in patients unable to communicate. PMID:26789007

  18. Basement faults and volcanic rock distributions in the Ordos Basin

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Volcanic rocks in the Ordos Basin are of mainly two types: one in the basin and the other along the margin of the basin. Besides those along the margin, the marginal volcanic rocks also include the volcanic rocks in the Yinshanian orogenic belt north of the basin. Based on the latest collection of gravitational and aeromagnetic data, here we interpret basement faults in the Ordos Basin and its peripheral region, compare the faults derived from aeromagnetic data with those from seismic data, and identify the geological ages of the fault development. Two aeromagnetic anomaly zones exist in the NE-trending faults of the southern basin, and they are in the volcanic basement formed in pre-Paleozoic. These NE-trending faults are the channel of volcanic material upwelling in the early age (Archean-Neoproterozoic), where igneous rocks and sedimentary rocks stack successively on both sides of the continental nucleus. In the Cambrian, the basin interior is relatively stable, but in the Late Paleozoic and Mesozoic, the basin margin underwent a number of volcanic activities, accompanied by the formation of nearly north-south and east-west basement faults in the basin periphery and resulting in accumulation of great amount of volcanic materials. Volcanic tuff from the basin periphery is discovered in the central basin and volcanic materials are exposed in the margins of the basin. According to the source-reservoir-cap rock configuration, the basin peripheral igneous traps formed in the Indosinian-Early Yanshanian and Late Hercynian are favorable exploration objectives, and the volcanic rocks in the central basin are the future target of exploration.

  19. Charcoal kiln relicts - a favorable site for tree growth?

    Science.gov (United States)

    Buras, Allan; Hirsch, Florian; van der Maaten, Ernst; Takla, Melanie; Räbiger, Christin; Cruz Garcia, Roberto; Schneider, Anna; Raab, Alexandra; Raab, Thomas; Wilmking, Martin

    2015-04-01

    Soils with incompletely combusted organic material (aka 'black carbon') are considered fertile for plant growth. Considerable enrichment of soils with black carbon is known from Chernozems, from anthropogenic induced altering of soils like the 'Terra Preta' in South America (e.g. Glaser, 2001), and from charcoal kiln relicts. Recent studies have reported a high spatial frequency of charcoal kiln relicts in the Northeastern German lowlands (Raab et al., 2015), which today are often overgrown by forest plantations. In this context the question arises whether these sites are favorable for tree growth. Here we compare the performance of 22 Pinus sylvestris individuals - a commonly used tree species in forestry - growing on charcoal kiln relicts with 22 control trees. Growth performance (height growth and diameter growth) of the trees was determined using dendrochronological techniques, i.e. standard ring-width measurements were undertaken on each two cores per tree and tree height was measured in the field. Several other wood properties such as annual wood density, average resin content, as well as wood chemistry were analyzed. Our results indicate that trees growing on charcoal kiln relicts grow significantly less and have a significantly lower wood density in comparison with control trees. Specific chemical components such as Manganese as well as resin contents were significantly higher in kiln trees. These results highlight that tree growth on charcoal kiln relicts is actually hampered instead of enhanced. Possibly this is a combined effect of differing physical soil properties which alter soil water accessibility for plants and differing chemical soil properties which may negatively affect tree growth either if toxic limits are surpassed or if soil nutrient availability is decreased. Additional soil analyses with respect to soil texture and soil chemistry shall reveal further insight into this hypothesis. Given the frequent distribution of charcoal kiln relicts in

  20. Uranium prospecting in the Iguatu and Frade basins (Brazil)

    International Nuclear Information System (INIS)

    The Mineral Exploration Department of CNEN studied the possibilities of uranium occurences in the Iguatu and Frade Basins in the preliminary research program designated 'Small Basins of the Northeast' which contitutes the object of this report. The two basins are located in the State of Ceara. The results of geologic and radiometric researches ahowed that the possibilities for uranium mineralizations were small, since the analyses of samples from the two main anomalies showed the radioactivity came from the remains of monazite. Further analysis of sedimentologic factors indicated favorable confitions for uranium concentration, taking into consideration the large variations of vertical and lateral granulometries, which permit spectulation about the flow of uraniferous solutions. radiometric measurements of surface samples were insignificant and no uranium mineral was found. The result of research of the sedimentary Frade Basin was negative for uranium mineralization. The basin was entirely eroded, remaining as an outcrop described in this report. (F.E.)

  1. 45 CFR 73.735-503 - Criminal provisions relating to gifts, entertainment, and favors.

    Science.gov (United States)

    2010-10-01

    ..., entertainment, and favors. 73.735-503 Section 73.735-503 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION STANDARDS OF CONDUCT Gifts, Entertainment, and Favors § 73.735-503 Criminal provisions relating to gifts, entertainment, and favors. (a) The law provides criminal penalties for...

  2. 49 CFR 805.735-5 - Receipt of gifts, entertainment, and favors by Members or employees.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Receipt of gifts, entertainment, and favors by... Receipt of gifts, entertainment, and favors by Members or employees. (a) Except as provided in paragraphs..., any gift, gratuity, favor, entertainment, loan, or any other thing of monetary value, from a...

  3. Uranium favorability of precambrian rocks in the Badger Flats - Elkhorn Thrust Area, Park and Teller Counties, Colorado

    International Nuclear Information System (INIS)

    The area is approximately 1,800 square miles and extends from Cripple Creek northward to Fairplay and Bailey. The Precambrian rocks include the metamorphic sequences of the Idaho Springs Formation and the Boulder Creek Granodiorite, Silver Plume Granite, Pikes Peak Granite, and Redskin Granite. The known uranium deposits in the area include six vein deposits, three pegmatite occurrences, and one zone of probable secondary enrichment; they have not yielded any significant production. The vein deposits are probably the result of downward percolation of ground water. The zone of secondary uranium enrichment may have formed above a volcanic pipe, vein, or tuffaceous lake bed. Favorability in the area is considered good for both vein and large, disseminated, low-grade uranium deposits. On the bases of known uranium occurrences, favorable structures and host rocks, and a water-sampling program, recommendations are given for exploration. The occurrences in the area have substantial similarities with the Rossing deposit in South-West Africa and the Wheeler Basin uranium occurrence in Grand County, Colorado. 6 figures, 9 tables

  4. Tectonic evolution of chagannuoer basin and its relationship to uranium metallogenetic process

    International Nuclear Information System (INIS)

    Starting from the tectonic evolution of the basin, authors expound the controlling role of the tectonic evolution of the basin upon factors closely associated with uranium metallogenesis in the basing such as the structure of the basin, filling sequence of cover deposit, hydrologic conditions and the mobilization and migration of uranium etc. It is suggested that the basin structure created favorable conditions for uranium ore-formation in Chagannuoer basin, it also controlled the genetic types of uranium mineralization, the distribution area and development intensity of uranium mineralization in the basin. Features of tectonic evolution resulted in the development of two type uranium mineralizations in the basin, i.e. phreatic oxidation and local interlayer oxidation types. (authors)

  5. 45 CFR 73.735-502 - Permissible acceptance of gifts, entertainment, and favors.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Permissible acceptance of gifts, entertainment... GENERAL ADMINISTRATION STANDARDS OF CONDUCT Gifts, Entertainment, and Favors § 73.735-502 Permissible acceptance of gifts, entertainment, and favors. (a) An employee may accept a gift, gratuity,...

  6. 45 CFR 73.735-501 - Prohibited acceptance of gifts, entertainment, and favors.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Prohibited acceptance of gifts, entertainment, and... ADMINISTRATION STANDARDS OF CONDUCT Gifts, Entertainment, and Favors § 73.735-501 Prohibited acceptance of gifts, entertainment, and favors. (a) Except as provided in §§ 73.735-502 and 73.735-506, an employee shall...

  7. Vertical movement in mare basins: relation to mare emplacement, basin tectonics, and lunar thermal history

    International Nuclear Information System (INIS)

    The spatial and temporal relationships of linear rilles and mare ridges in the Serenitatis basin region of the moon are explained by a combination of lithospheric flexure in response to basin loading by basalt fill and a time-dependent global stress due to the thermal evolution of the lunar interior. The pertinent tectonic observations are the radial distance of basin concentric rilles or graben from the mare center; the location and orientation of mare ridges, interpreted as compressive features; and the restriction of graben formation to times older than 3.6 +- 0.2 b.y. ago, while ridge formation continued after emplacement of the youngest mare basalt unit (approx.3 b.y. ago). The locations of the graben are consistent with the geometry of the mare basalt load expected from the dimensions of multiring basins for values of the thickness of the elastic lithosphere beneath Serenitatis in the range 25--50 km at 3.6--3.8 b.y. ago. The locations and orientations of mare ridges are consistent with the load inferred from surface mapping and subsurface radar reflections for values of the elastic lithosphere thickness near 100 km at 3.0--3.4 b.y. ago. The thickening of the lithosphere beneath a major basin during the evolution of mare volcanism is thus clearly evident in the tectonics. The cessation of rille formation and the prolonged period of ridge formation are attributed to a change in the global horizontal thermal stress from extension to compression as the moon shifted from net expansion to overall cooling and contraction. Severe limits as placed on the range of possible lunar thermal histories. The zone of horizontal extensional stresses peripheral to mare loads favors the edge of mare basins as the preferred sites for mare basalt magma eruption in the later stages of mare fill, although subsidence may lead to accumulation of such young lavas in basin centers

  8. Mechanism of Secondary Pore Formation and Prediction of Favorable Reservoir of Paleogene in Jiyang Sag,Eastern China

    Institute of Scientific and Technical Information of China (English)

    Zhu Xiaomin; Chen Huanqing; Zhong Dakang; Zhang Qin; Zhang Shanwen; Lü Xixue

    2008-01-01

    Jiyang (济阳) sag is an oil rich basin,consisting of Huimin (惠民),Dongying (东营),Zhanhua (沾化),and Chezhen (车镇) depressions.The elastic rock of Paleogene has undergone early and middle diagenetic stages and now the main clastic reservoir is in the middle diagenetic stage.Primary and secondary pores are developed in Paleogene sandstone,the latter is generated from the dissolution of feldspar and calcite cement in rocks owing to the organic acid from the maturated source rock,but the materials dissolved are different in different depressions.The reservoir secondary pores of Dongying depression are generated from the dissolution of calcite cement,the ones of Zhanhua and Huimin depressions from the dissolution of feldspar,the secondary pores of Chezhen depression from the dissolution of feldspar in upper section,and the dissolution of calcite cement in the lower section of Paleogene,respectively.The secondary pores are developed in two depths and the depth goes down from west to east,from south to north in Jiyang sag.The major controlling factors for secondary pore development are maturity and location of source rock.Lastly,the favorable reservoirs are evaluated according to reservoir buried depth,sedimentation,and diagenesis.The reservoir with high quality is located in the northern and central parts in Dongying depression; there are some good reservoirs in Gndao (孤岛),Gudong (孤东),and Gunan (孤南) areas in Zhanhua depression,and the favorable reservoirs are located in the north steep slope and the south gentle slope of Chezhen depression and central uplift,south gentle slope of Huimin depression.

  9. Exploration orientation of leachable sandstone type uranium deposit in Erlian basin

    International Nuclear Information System (INIS)

    Erlian basin is a large meso-cenozoic uraniferous basin.Great achievement of leachable sandstone type uranium deposit exploration has been made in the basin in recent years. By systematicaly summarizing and analyzing exploratory results, this article has established the principle for ascertaining target layer and put forward Saihan formation as the main target layer and Erlian formation and Yierdingmanha formation as the secondary target layers for uranium exploration in Erlian basin. The exploratory type in Erlian basin is inter-layered oxidation type(including phreatic-interlayer type). Besides, this article summarizes the criterions for uranium exploration and analyzes the exploratory prospect and orientation. The paper points out that the south edge of Bayinbaolige uplift (northern part of Wulanchabu depression and Manite depression) is the most favorable area for leachable sandstone type uranium deposits exploration in Erlian basin. (authors)

  10. Melo carboniferous basin

    International Nuclear Information System (INIS)

    This report is about of the Melo carboniferous basin which limits are: in the South the large and high Tupambae hill, in the west the Paraiso hill and the river mountains, in the North Yaguaron river basin to Candidata in Rio Grande del Sur in Brazil.

  11. On the formations of the Pampas inthe footsteps of Darwin: south of the Salado Sobre las formaciones de las Pampasen los pasos de Darwin: al sur del Salado

    Directory of Open Access Journals (Sweden)

    Marcelo Zárate

    2009-04-01

    Full Text Available In1833 during his journey across the Buenos Aires Pampas, Charles Darwin madeobservations that reflected his thoughts on two major landscape units, Pampa interserrana and Pampa deprimida, later identified byother authors. Darwin grouped the Pampean sediments into a single unit, the PampeanFormation, based upon the lithological homogeneity and the large extensionof the deposits; the unit was thought to be of estuarine-marine origin andattributed to the Recent Epoch considering the paleontological content(vertebrates and mollusks. At present, the Pampean sedimentary succession,which accumulated approximately during the last 11-12 Ma, is interpreted as a pedosedimentarysequence due to the ubiquity of pedogenetic features throughout the deposits.Four main subcycles of sedimentation are identified related to reactivations ofthe Pampean landscape. At a regional scale, the outcrop distribution of Pampeansediments of different ages suggests the dominance of more stable conditionssince the late Miocene-Pliocene in a vast area of Pampa interserrana, documented by theformation of calcretes. However, sedimentation during the latePliocene-Pleistocene was active within the domain of the Salado tectonic basin andSierras de Tandil. The regional disparity shown by the Pampean stratigraphicrecord reveals the major morphostructural differences of its basement.Durante su viaje por la Pampa bonaerense en 1833 CharlesDarwin efectuó observaciones que reflejaban las dos grandes unidades de paisajeposteriormente reconocidas en la región, la Pampa interserrana y la Pampadeprimida. La homogeneidad litológica y la vasta extensión de los depósitosfueron los criterios básicos empleados para agruparlos en una única unidad, la FormaciónPampeano; basado en criterios paleontológicos le atribuyó origenestuárico-marino y la asignó a la época Reciente. Si bien han existido otraspropuestas estratigráficas, Formación Pampeano o simplemente Pampeano, sondenominaciones

  12. K Basin safety analysis

    International Nuclear Information System (INIS)

    The purpose of this accident safety analysis is to document in detail, analyses whose results were reported in summary form in the K Basins Safety Analysis Report WHC-SD-SNF-SAR-001. The safety analysis addressed the potential for release of radioactive and non-radioactive hazardous material located in the K Basins and their supporting facilities. The safety analysis covers the hazards associated with normal K Basin fuel storage and handling operations, fuel encapsulation, sludge encapsulation, and canister clean-up and disposal. After a review of the Criticality Safety Evaluation of the K Basin activities, the following postulated events were evaluated: Crane failure and casks dropped into loadout pit; Design basis earthquake; Hypothetical loss of basin water accident analysis; Combustion of uranium fuel following dryout; Crane failure and cask dropped onto floor of transfer area; Spent ion exchange shipment for burial; Hydrogen deflagration in ion exchange modules and filters; Release of Chlorine; Power availability and reliability; and Ashfall

  13. K Basin safety analysis

    Energy Technology Data Exchange (ETDEWEB)

    Porten, D.R.; Crowe, R.D.

    1994-12-16

    The purpose of this accident safety analysis is to document in detail, analyses whose results were reported in summary form in the K Basins Safety Analysis Report WHC-SD-SNF-SAR-001. The safety analysis addressed the potential for release of radioactive and non-radioactive hazardous material located in the K Basins and their supporting facilities. The safety analysis covers the hazards associated with normal K Basin fuel storage and handling operations, fuel encapsulation, sludge encapsulation, and canister clean-up and disposal. After a review of the Criticality Safety Evaluation of the K Basin activities, the following postulated events were evaluated: Crane failure and casks dropped into loadout pit; Design basis earthquake; Hypothetical loss of basin water accident analysis; Combustion of uranium fuel following dryout; Crane failure and cask dropped onto floor of transfer area; Spent ion exchange shipment for burial; Hydrogen deflagration in ion exchange modules and filters; Release of Chlorine; Power availability and reliability; and Ashfall.

  14. Distribution of calcretes and gypcretes in southwestern United States and their uranium favorability, based on a study of deposits in Western Australia and South West Africa (Namibia)

    International Nuclear Information System (INIS)

    Calcrete, dolocrete, and gypcrete carnotite are abundant in western Australia and Namib Desert, although only a few are of ore grade. The geology of these deposits are described. A genetic classification of calcretes emphasizing uranium favorability was developed, based on the distinction between pedogenic and nonpedogenic processes. Similarities between western Australia and South West Africa give support for the conclusions that lateral transport of U in groundwater is essential to ore deposition and that bedrock barriers or constrictions which narrow the channel of subsurface flow or force the water close to the land surface, greatly favor the formation of uraniferous calcretes. Criteria for uranium favorability deduced from the Australian and South West African studies were applied in a preliminary way to the southern Basin and Range Province of U.S. The procedure is to search for areas in which nonpedogenic calcrete or gypcrete may have developed. A caliche distribution map was compiled from soil survey and field data. Many areas were visited and some of the more interesting are described briefly, including parts of Clark County, Nevada, with occurrences of carnotite in calcrete

  15. Distribution of calcretes and gypcretes in southwestern United States and their uranium favorability, based on a study of deposits in Western Australia and South West Africa (Namibia)

    Energy Technology Data Exchange (ETDEWEB)

    Carlisle, D.; Merifield, P.M.; Orme, A.R.; Kohl, M.S.; Kolker, O.; Lunt, O.R.

    1978-01-06

    Calcrete, dolocrete, and gypcrete carnotite are abundant in western Australia and Namib Desert, although only a few are of ore grade. The geology of these deposits are described. A genetic classification of calcretes emphasizing uranium favorability was developed, based on the distinction between pedogenic and nonpedogenic processes. Similarities between western Australia and South West Africa give support for the conclusions that lateral transport of U in groundwater is essential to ore deposition and that bedrock barriers or constrictions which narrow the channel of subsurface flow or force the water close to the land surface, greatly favor the formation of uraniferous calcretes. Criteria for uranium favorability deduced from the Australian and South West African studies were applied in a preliminary way to the southern Basin and Range Province of U.S. The procedure is to search for areas in which nonpedogenic calcrete or gypcrete may have developed. A caliche distribution map was compiled from soil survey and field data. Many areas were visited and some of the more interesting are described briefly, including parts of Clark County, Nevada, with occurrences of carnotite in calcrete. (DLC)

  16. Discussion on the basement topography and its relation with the uranium mineralization in Xiangshan basin

    International Nuclear Information System (INIS)

    The depth of the basement and the relation between the basement relief shape and uranium mineralization are discussed by forward and inverse computation for large-scale gravity data in Xiangshan basin. The difference of basement topography result in the inhomogeneous distribution of uranium mineralization. The margin of the basement upheaval section and the variation place of basement topography are the favorable place for uranium mineralization. It's helpful to prospect deep and blind uranium deposit in Xiangshan basin

  17. Geothermal Favorability Map Derived From Logistic Regression Models of the Western United States (favorabilitysurface.zip)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This is a surface showing relative favorability for the presence of geothermal systems in the western United States. It is an average of 12 models that correlates...

  18. Integrated Theoretical Framework for a Homeowner's Decision in Favor of an Innovative Residential Heating System

    OpenAIRE

    Michelsen , Carl Christian; Madlener, Reinhard

    2010-01-01

    Insight into the homeowner’s adoption decisions in favor of a specific innovative residential heating system (RHS) helps us to understand and assess the dynamics of the adoption and diffusion of such technological systems as a “social” phenomenon. This phenomenon emerges from the individual decisions of a set of heterogeneous actors on the market. In our research, we develop an integrated theoretical framework for assessing a homeowner’s adoption decision in favor of a specific innovative RHS...

  19. Uranium favorability of late Eocene through Pliocene rocks of the South Texas Coastal Plain

    Energy Technology Data Exchange (ETDEWEB)

    Quick, J.V.; Thomas, N.G.; Brogdon, L.D.; Jones, C.A.; Martin, T.S.

    1977-02-01

    The results of a subsurface uranium favorability study of Tertiary rocks (late Eocene through Pliocene) in the Coastal Plain of South Texas are given. In ascending order, these rock units include the Yegua Formation, Jackson Group, Frio Clay, Catahoula Tuff, Oakville Sandstone, and Goliad Sand. The Vicksburg Group, Anahuac Formation, and Fleming Formation were not considered because they have unfavorable lithologies. The Yegua Formation, Jackson Group, Frio Clay, Catahoula Tuff, Oakville Sandstone, and Goliad Sand contain sandstones that may be favorable uranium hosts under certain environmental and structural conditions. All except the Yegua are known to contain ore-grade uranium deposits. Yegua and Jackson sandstones are found in strand plain-barrier bar systems that are aligned parallel to depositional and structural strike. These sands grade into shelf muds on the east, and lagoonal sediments updip toward the west. The lagoonal sediments in the Jackson are interrupted by dip-aligned fluvial systems. In both units, favorable areas are found in the lagoonal sands and in sands on the updip side of the strand-plain system. Favorable areas are also found along the margins of fluvial systems in the Jackson. The Frio and Catahoula consist of extensive alluvial-plain deposits. Favorable areas for uranium deposits are found along the margins of the paleo-channels where favorable structural features and numerous optimum sands are present. The Oakville and Goliad Formations consist of extensive continental deposits of fluvial sandstones. In large areas, these fluvial sandstones are multistoried channel sandstones that form very thick sandstone sequences. Favorable areas are found along the margins of the channel sequences. In the Goliad, favorable areas are also found on the updip margin of strand-plain sandstones where there are several sandstones of optimum thickness.

  20. Wada basin boundaries and basin cells

    NARCIS (Netherlands)

    Nusse, H.E.; Yorke, J.A.

    1996-01-01

    In dynamical systems examples are common in which two or more attractors coexist, and in such cases the basin boundary is nonempty. We consider a two-dimensional diffeomorphism F (that is, F is an invertible map and both F and its inverse are differentiable with continuous derivatives), which has at

  1. Reserves in western basins

    Energy Technology Data Exchange (ETDEWEB)

    Caldwell, R.H.; Cotton, B.W. [Scotia Group, Dallas, TX (United States)

    1995-04-01

    The objective of this project is to investigate the reserves potential of tight gas reservoirs in three Rocky Mountain basins: the Greater Green River (GGRB), Uinta and Piceance basins. The basins contain vast gas resources that have been estimated in the thousands of Tcf hosted in low permeability clastic reservoirs. This study documents the productive characteristics of these tight reservoirs, requantifies gas in place resources, and characterizes the reserves potential of each basin. The purpose of this work is to promote understanding of the resource and to encourage its exploitation by private industry. At this point in time, the GGRB work has been completed and a final report published. Work is well underway in the Uinta and Piceance basins which are being handled concurrently, with reports on these basins being scheduled for the middle of this year. Since the GGRB portion of the project has been completed, this presentation win focus upon that basin. A key conclusion of this study was the subdivision of the resource, based upon economic and technological considerations, into groupings that have distinct properties with regard to potential for future producibility, economics and risk profile.

  2. Geological conditions of coal and gas(oil)-bearing basins in China

    Institute of Scientific and Technical Information of China (English)

    WANG; Tingbin

    2005-01-01

    There are various types of coal basins in China. Indosinian movement can be regarded as their evolutionary limit, and the basins can be divided into two developmental stages, three structural patterns and two sedimentary environments. However, only those coal measure strata that have been deeply buried in the earth are possible to be converted into coal and gas (oil)-bearing basins. Among which, only part of the coal measures possess the essential geological conditions to the formation of commercial humic oil. However, humic gas will be the major exploration target for natural gas in China. Among various coal basins, foreland basins have the best prospect for humic gas. Rift (faulted) basins accumulate the most abundance of humic gas, and are most favorable to generate humic oil. Craton basins have relatively low abundance of humic gas, but the evolution is rather great. The three kinds of coal basins mentioned above constitute China's three primary accumulation areas of humic gas: western, central and offshore areas. The major basins for humic gas field exploration include Tarim, Ordos, Sichuan, East China Sea and Yingqiong basins.

  3. Evolutionary sequences and hydrocarbon potential of Kenya sedimentary basins

    Energy Technology Data Exchange (ETDEWEB)

    Cregg, A.K. (Western Atlas International, Inc., Carrollton, TX (United States))

    1991-03-01

    Kenya basins have evolved primarily through extension related to episodic continental rifting. In eastern Kenya, thick accumulations of sediments formed within grabens during the prerift phase (Precambrian to Carboniferous) of the Gondwana breakup. Synrift sedimentation (Late Carboniferous to Middle Jurassic) occurred within a north-south rift system, which included the Mandera basin, South Anza basin, and Lamu embayment. During the Early Jurassic, a marine transgression invaded the margins of the eastern Kenya rift basins, resulting in the deposition of platform carbonates and shales. A Callovian-aged salt basin formed in the offshore regions of the Lamu embayment. Intermittent tectonic activity and eustatic sea-level changes controlled sedimentation, which produced marine shales, carbonates or evaporites, and fluvio-deltaic to lacustrine sandstones. From the Early Cretaceous to recent, continental sediments were deposited within the North Anza and Turkana basins. These fluvial-lacustrine sediments are similar to the Lower Cretaceous sequences that have produced oil in the Mesozoic Sudanese Abu Gabra rift. Although exploration activities began in the early 1950s, significant occurrences of potential reservoir, source, and seal lithologies as well as trapping configurations remain in many areas. Favorable structures and sequences of reservoir sandstones and carbonates overlain by potentially sealing lacustrine or marine shales, evaporites, or volcanics have been noted. Potential source beds are believed to be present within shales of the lacustrine or marine depositional environments.

  4. Modeling Nitrogen Losses under Rapid Infiltration Basins

    Science.gov (United States)

    Akhavan, M.; Imhoff, P. T.; Andres, A. S.; Finsterle, S.

    2011-12-01

    pore water and a dimensionless parameter, Fs, is used to represent degree of DNF for different operating conditions. TOUGHREACT is also used for comprehensive modeling of N fate and transport. Flow and transport simulations indicate that discharging wastewater in less permeable soils results in more water spreading over the basin and larger saturated area under the basin, which is more favorable for DNF resulting in higher nitrogen removal than in more permeable basin soils. Moreover, smaller ratios of wetting to drying time, i.e., shorter but more intense flooding periods, result in higher vadose zone water saturations and as a result greater DNF. Using a coupled surface-subsurface model to predict DNF is very important particularly when basin flooding occurs at high rates for short periods.

  5. Permian Basin location recommendation report

    International Nuclear Information System (INIS)

    Candidate study areas are screened from the Palo Duro and Dalhart Basin areas using data obtained from studies to date and criteria and specifications that consider: rock geometry; rock characteristics; human intrusion potential; surface characteristics; and environmental and socioeconomic conditions. Two preferred locations are recommended from among these areas for additional characterization to identify potential National Waste Terminal Storage (NWTS) salt repository sites. One location, in northeastern Deaf Smith County and southeastern Oldham County, is underlain by two salt units that meet the adopted screening specifications. The other location, in northcentral Swisher County, is underlain by one salt unit that meets the adopted screening specifications. Both locations have several favorable features, relative to surrounding areas, and no obviously undesirable characteristics. Both lie wholly on the Southern High Plains surface, are in relatively sparsely populated areas, contain no unique land use conflicts, and comprise large enough geographic areas to provide flexibility in site selection. Data gathered to date indicate that these locations contain salt units sufficient in thickness and in depth for the safe construction and operation of the underground facilities under consideration. 93 references, 34 figures, 6 tables

  6. Lithologic Hydrocarbon Deposits in Rift Lake Basins in Eastern China

    Institute of Scientific and Technical Information of China (English)

    ZHENG Herong; HE Zongquan

    2004-01-01

    The rift lake basins in the eastern China have abundant hydrocarbon resources of lithologic deposits, which resulted from excellent source rocks and multi-type sandbodies developed during strong rifting. Vertically, the lithologic deposits are mainly distributed in the lowstand, lacustrine invasion and early highstand systems of third-order sequence corresponding to a secondary tectonic episode of strong rifting, and laterally they are closely related to various fans and turbidite sandbodies controlled by syn-sedimentary faults. A variety of lithologic traps have been developed in the rift lake basins, and they generally have favorable conditions of source-reservoir-seal assemblage and hydrocarbon accumulation dynamics, indicating that there is a great exploration potential of lithologic deposits in the rift lake basins.In order to obtain satisfactory effects of lithologic deposit exploration, it is required to combine new theories with advanced technical methods.

  7. Early Mesozoic basin aquifers

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set represents the extent of the Early Mesozoic basin aquifers in the states of Massachusettes, Connecticut, New York, New Jersey, Pennsylvania, Maryland,...

  8. Mitigation : Closed Basin Project

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The upcoming meeting on waterfowl mitigation for the Closed Basin Project will have several people talk about possible changes to the waterfowl mitigation program....

  9. Tulare Basin protection plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Tulare Basin Protection Plan has been initiated by The Nature Conservancy to elucidate the problems and opportunities of natural diversity protection....

  10. California Air Basins

    Data.gov (United States)

    California Department of Resources — Air ResourcesCalifornia Air Resources BoardThe following datasets are from the California Air Resources Board: * arb_california_airbasins - California Air BasinsThe...

  11. K Basin Hazard Analysis

    International Nuclear Information System (INIS)

    This report describes the methodology used in conducting the K Basins Hazard Analysis, which provides the foundation for the K Basins Final Safety Analysis Report. This hazard analysis was performed in accordance with guidance provided by DOE-STD-3009-94, Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports and implements the requirements of DOE Order 5480.23, Nuclear Safety Analysis Report

  12. K Basins Hazard Analysis

    International Nuclear Information System (INIS)

    This report describes the methodology used in conducting the K Basins Hazard Analysis, which provides the foundation for the K Basins Safety Analysis Report (HNF-SD-WM-SAR-062/Rev.4). This hazard analysis was performed in accordance with guidance provided by DOE-STD-3009-94, Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports and implements the requirements of DOE Order 5480.23, Nuclear Safety Analysis Report

  13. The Ebro river basin

    OpenAIRE

    Darbra Roman, Rosa Maria

    2011-01-01

    River basins worldwide are under pressure from economic activities. In Europe, the two main factors hindering the achievement of good chemical and ecological status of European river basins are pollution, mainly coming from agriculture, and hydromorphology (e.g. for navigation, hydroelectricity and flood control). The economic activities affect the chemical and ecological status of rivers, lakes and groundwater and deplete available soil, sediments and water resources. The w...

  14. Uranium favorability of tertiary sedimentary rocks of the Pend Oreille River valley, Washington

    International Nuclear Information System (INIS)

    Tertiary sedimentary rocks in the Pend Oreille River valley were investigated in a regional study to determine the favorability for potential uranium resources of northeastern Washington. This project involved measurement and sampling of surface sections, collection of samples from isolated outcrops, chemical and mineralogical analyses of samples, and examination of available water well logs. The Box Canyon Dam area north of Ione is judged to have very high favorability. Thick-bedded conglomerates interbedded with sandstones and silty sandstones compose the Tiger Formation in this area, and high radioactivity levels are found near the base of the formation. Uranophane is found along fracture surfaces or in veins. Carbonaceous material is present throughout the Tiger Formation in the area. Part of the broad Pend Oreille valley surrounding Cusick, Washington, is an area of high favorability. Potential host rocks in the Tiger Formation, consisting of arkosic sandstones interbedded with radioactive shales, probably extend throughout the subsurface part of this area. Carbonaceous material is present and some samples contain high concentrations of uranium. In addition, several other possible chemical indicators were found. The Tiger-Lost Creek area is rated as having medium favorability. The Tiger Formation contains very hard, poorly sorted granite conglomerate with some beds of arkosic sandstone and silty sandstone. The granite conglomerate was apparently derived from source rocks having relatively high uranium content. The lower part of the formation is more favorable than the upper part because of the presence of carbonaceous material, anomalously high concentrations of uranium, and other possible chemical indicators. The area west of Ione is judged to have low favorability, because of the very low permeability of the rocks and the very low uranium content

  15. La Cautela Socini como salvaguarda del patrimonio familiar en favor del cónyuge viudo.

    OpenAIRE

    García Palicio, Eduardo

    2016-01-01

    El presente trabajo se encuentra dividido en cuatro bloques a través el lector podrá ver el funcionamiento de la Cautela Socini respecto al usufructo universal en favor del cónyuge viudo y los derechos de los herederos forzosos del causante. En un primer bloque, encontramos un estudio de los derechos legitimarios que le son reconocidos al cónyuge viudo en el Código Civil, continuando con un segundo bloque en el que se realiza un análisis de la figura del usufructo universal en favor del cónyu...

  16. Predicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored Allele

    Science.gov (United States)

    Zakov, Shay; Rosenberg, Noah A.; Bafna, Vineet

    2015-01-01

    Methods for detecting the genomic signatures of natural selection have been heavily studied, and they have been successful in identifying many selective sweeps. For most of these sweeps, the favored allele remains unknown, making it difficult to distinguish carriers of the sweep from non-carriers. In an ongoing selective sweep, carriers of the favored allele are likely to contain a future most recent common ancestor. Therefore, identifying them may prove useful in predicting the evolutionary trajectory—for example, in contexts involving drug-resistant pathogen strains or cancer subclones. The main contribution of this paper is the development and analysis of a new statistic, the Haplotype Allele Frequency (HAF) score. The HAF score, assigned to individual haplotypes in a sample, naturally captures many of the properties shared by haplotypes carrying a favored allele. We provide a theoretical framework for computing expected HAF scores under different evolutionary scenarios, and we validate the theoretical predictions with simulations. As an application of HAF score computations, we develop an algorithm (PreCIOSS: Predicting Carriers of Ongoing Selective Sweeps) to identify carriers of the favored allele in selective sweeps, and we demonstrate its power on simulations of both hard and soft sweeps, as well as on data from well-known sweeps in human populations. PMID:26402243

  17. The Changing Format of Reference Collections: Are Research Libraries Favoring Electronic Access over Print?

    Science.gov (United States)

    Robbins, Sarah; McCain, Cheryl; Scrivener, Laurie

    2006-01-01

    This study examines the holdings of ARL libraries for core reference titles to see if there is a trend towards canceling the print in favor of electronic, and discusses the implications of duplication of titles in both formats. It also looks at the issue within the context of several areas of study including general reference, arts and humanities,…

  18. Postmating sexual selection favors males that sire offspring with low fitness

    DEFF Research Database (Denmark)

    Bilde, T.; Foged, Anne; Schilling, Nadia;

    2009-01-01

    Despite the costs of mating, females of most taxa mate with multiple males. Polyandrous females are hypothesized to gain genetic benefits for their offspring, but this assumes paternity bias favoring male genotypes that enhance offspring viability. We determined net male genetic effects on female...

  19. Biofilm Mode of Growth of Streptococcus intermedius Favored by a Competence-Stimulating Signaling Peptide

    OpenAIRE

    Petersen, Fernanda C; Pecharki, Daniele; Scheie, Anne A.

    2004-01-01

    Gram-positive and gram-negative bacteria use quorum sensing to coordinate population behavior. In several streptococci, quorum sensing mediated by competence-stimulating peptides (CSP) is associated with development of competence for transformation. We show here that a synthetic CSP favored the biofilm mode of growth of Streptococcus intermedius without affecting the rate of culture growth.

  20. Area geological characterization report for the Palo Duro and Dalhart Basins, Texas

    International Nuclear Information System (INIS)

    The present state of knowledge of the geology, hydrogeology, and seismology of the Palo Duro and Dalhart basins is summarized as a basis for future siting studies for a high-level nuclear waste repository. Large portions of the Texas Panhandle, and especially the Palo Duro basin, have stable geologic conditions and a favorable evaporite stratigraphy that warrant further study. Five salt-bearing formations containing thick salt units are present within the basin. Salt beds appear to be persistent over wide areas, relatively flat lying and structurally undisturbed. Available hydrogeologic data suggest that favorable conditions for waste isolation are widespread. The level and rate of seismic activity are low throughout the Texas Panhandle. 335 references, 83 figures, 17 tables

  1. WiBasin: basin management through an integrated platform

    OpenAIRE

    Llort Pavon, Xavier; Sánchez-Diezma Guijarro, Rafael; Sancho, David; Rodríguez, Álvaro; Berenguer Ferrer, Marc; Sempere Torres, Daniel

    2014-01-01

    In this work we present WiBasin, a cloud platform for basin and dam management. It includes different sources of precipitation (both observed and forecasted), integration over the catchment domain (to provide an aggregated value of potential rainfall accumulated over the basin) , and a complete dissemination environment (web-viewer, capability of issuing hazard warnings with configurable thresholds, SMS, mails, etc.)

  2. Modifed Great Basin Extent (Buffered)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Two different great basin perimeter files were intersected and dissolved using ArcGIS 10.2.2 to create the outer perimeter of the great basin for use modeling...

  3. Uranium deposits: northern Denver Julesburg basin, Colorado

    International Nuclear Information System (INIS)

    The Fox Hills Sandstone and the Laramie Formation (Upper Cretaceous) are the host rocks for uranium deposits in Weld County, northern Denver Julesburg basin, Colorado. The uranium deposits discovered in the Grover and Sand Creek areas occur in well-defined north--south trending channel sandstones of the Laramie Formation whereas the sandstone channel in the upper part of the Fox Hills Sandstone trends east--west. Mineralization was localized where the lithology was favorable for uranium accumulation. Exploration was guided by log interpretation methods similar to those proposed by Bruce Rubin for the Powder River basin, Wyoming, because alteration could not be readily identified in drilling samples. The uranium host rocks consist of medium- to fine-grained carbonaceous, feldspathic fluvial channel sandstones. The uranium deposits consist of simple to stacked roll fronts. Reserve estimates for the deposits are: (1) Grover 1,007,000 lbs with an average grade of 0.14 percent eU3O8,2) Sand Creek 154,000 lbs with an average grade of 0.08 percent eU3O8, and 3) The Pawnee deposit 1,060,000 lbs with an average grade of 0.07 percent eU3O8. The configuration of the geochemical cells in the Grover and Sand Creek sandstones indicate that uraniferous fluids moved northward whereas in the Pawnee sandstone of the Fox Hills uraniferous fluids moved southward. Precipitation of uranium in the frontal zone probably was caused by downdip migration of oxygcnated groundwater high in uranium content moving through a favorable highly carbonaceous and pyritic host sandstone

  4. Reversing the indus basin closure

    OpenAIRE

    2011-01-01

    After independence, a swift and extensive development of Indus river basin has intensified commitment of water resources. During dry period, the indication of over commitment and basin closure are visible. In the beginning 2000s, he river basin water resources were committed to more than 99% without any environmental flows. The paper tries to unfold drivers closing the Indus basin and the scope for change. Defining and implementing water allocation mechanism to ascertain equity, sustainabilit...

  5. Influences of Mental Illness Stigma on Perceptions of and Responses to Requests for Favors.

    Science.gov (United States)

    Imai, Tatsuya; Dailey, René

    2016-07-01

    This article examines mental illness stigma effects on a request for a favor from a mentally ill individual. Four hundred and fourteen participants interacted with a hypothetical target on Facebook who was believed to have schizophrenia, depression, or a tooth cavity (i.e., the control group). Participants were asked to rate the favor request in terms of face threat, in addition to writing a response, which was then coded using message design logics. Results indicated that a request by a schizophrenic target threatened participants' positive face more significantly than that of a target with depression or without any mental illness. Participants' responses to the schizophrenic target were more likely to be conventional messages, whereas responses to the depressed target were more likely to be rhetorical messages. Theoretical and practical contributions are considered. PMID:26642875

  6. Perceived Distributive Fairness of EU Transfer Payments, Outcome Favorability, Identity, and EU-Tax Compliance.

    Science.gov (United States)

    Hartner, Martina; Rechberger, Silvia; Kirchler, Erich; Wenzel, Michael

    2011-01-01

    In a representative UK study (N = 1000) the link between distributive fairness perceptions, outcome favorability, identity, and tax compliance was researched in the context of European transfer payments. Results showed that both forms of tax compliance (i.e., individual and collective EU-tax compliance) were influenced by perceived distributive fairness judgments of EU transfer payments. Fairness itself was related to perceived outcome favorability (i.e., whether their own nation benefits from the EU in financial as well as socio-political terms). Additionally, national identifiers (i.e., people identifying with their own nation, but not with Europe) perceived EU membership as unbeneficial in financial as well as in socio-political terms and thus considered the transfer payments as less fair. Dual identifiers (i.e., people identifying with their own nation and with Europe) perceived the socio-political outcomes from EU membership as more beneficial and thus evaluated the transfer payments as fairer. PMID:21412442

  7. Uranium favorability evaluation of the Mt. Withington cauldron, Socorro County, New Mexico

    International Nuclear Information System (INIS)

    The Mt. Withington cauldron is unfavorable for initial-magmatic pneumatogenic, hydroauthigenic, and hydroallogenic uranium deposits. Despite their favorable major-oxide chemistry, the rocks in the cauldron are relatively poor uranium source rocks; evidence for significant uranium mobilization and transport is lacking; the ash-flow tuffs and the domes and lava flows do not have porous structures adequate to accommodate uranium precipitated by pressure-temperature mechanisms in amounts large enough to constitute uranium deposits; and the lack of reductants signifies that uranium precipitation in adequate amounts by reduction is not probable. It is concluded that no further uranium favorability work in the Mt. Withington cauldron is warranted. 1 figure, 1 table

  8. Detecting Two-Spirit erotics: The fiction of Carole laFavor.

    Science.gov (United States)

    Tatonetti, Lisa

    2016-01-01

    This article examines the life and novels of Carole laFavor, arguing for her importance to and influence in Two-Spirit studies. Along with being a writer, laFavor was a powerful voice for social justice and Indigenous health sovereignty in Minnesota and the nation. Her two novels, Along the Journey River and Evil Dead Center, which both focus on Anishinaabe lesbian detective protagonist Renee LaRoche, are the first lesbian detective fiction published by a Native author. Renee's embrace of a specifically Two-Spirit erotics anchors her to family and brings her tribal community a powerful healing when she employs her skills to protect her people from instances of racism, abuse, and injustice. This article, then, reads these novels as the first of an emerging genre of texts that claim an overtly Two-Spirit erotic as well as vital precursors to the present embrace of sovereign erotics in Indigenous studies. PMID:27254762

  9. Favorable Long-term Prognosis of Cataract Surgery in Herpes Zoster Ophthalmicus

    Science.gov (United States)

    Chaudhary, Kulbhushan Prakash; Mahajan, Deepti; Panwar, Praveen

    2016-01-01

    Purpose: Scleritis is a rare presentation of herpes zoster ophthalmicus, complicated most commonly by iridocyclitis and raised intraocular pressure. These complications can recur in subsequent years, therefore they should be managed well. Case Report: We describe a female patient who developed scleritis, complicated cataract and secondary glaucoma 2 years after being diagnosed by HZO. Secondary glaucoma was managed medically, and the patient underwent extracapsular cataract extraction for the complicated cataract. Final visual acuity was 6/6 and IOP was 22.4 mm Hg. This is a rare report describing favorable long-term (>20 years) prognosis for surgical management of cataract associated with HZO together with scleritis, secondary glaucoma and post-herpetic neuralgia. Conclusion: A favorable outcome may be attained with surgery for complicated cataract associated with HZO if the condition is managed optimally and intraocular inflammation is well controlled. PMID:27413505

  10. Rational selection of structurally diverse natural product scaffolds with favorable ADME properties for drug discovery.

    Science.gov (United States)

    Samiulla, D S; Vaidyanathan, V V; Arun, P C; Balan, G; Blaze, M; Bondre, S; Chandrasekhar, G; Gadakh, A; Kumar, R; Kharvi, G; Kim, H O; Kumar, S; Malikayil, J A; Moger, M; Mone, M K; Nagarjuna, P; Ogbu, C; Pendhalkar, D; Rao, A V S Raja; Rao, G Venkateshwar; Sarma, V K; Shaik, S; Sharma, G V R; Singh, S; Sreedhar, C; Sonawane, R; Timmanna, U; Hardy, L W

    2005-01-01

    Natural product analogs are significant sources for therapeutic agents. To capitalize efficiently on the effective features of naturally occurring substances, a natural product-based library production platform has been devised at Aurigene for drug lead discovery. This approach combines the attractive biological and physicochemical properties of natural product scaffolds, provided by eons of natural selection, with the chemical diversity available from parallel synthetic methods. Virtual property analysis, using computational methods described here, guides the selection of a set of natural product scaffolds that are both structurally diverse and likely to have favorable pharmacokinetic properties. The experimental characterization of several in vitro ADME properties of twenty of these scaffolds, and of a small set of designed congeners based upon one scaffold, is also described. These data confirm that most of the scaffolds and the designed library members have properties favorable to their utilization for creating libraries of lead-like molecules. PMID:15789560

  11. South Bohemian basins

    Czech Academy of Sciences Publication Activity Database

    Spudil, J.; Brož, B.; Dašková, Jiřina; Holcová, K.; Kvaček, Z.; Pešek, J.; Svobodová, Marcela; Sýkorová, Ivana; Teodoridis, V.

    Prague: Czech Geological Survey, 2014, s. 190-206 ISBN 978-80-7075-862-5 R&D Projects: GA ČR GA105/06/0653 Institutional support: RVO:67985891 ; RVO:67985831 Keywords : Tertiary basins * Czech Republic * Cenomanian and Tertiary lignite * geology * stratigraphy Subject RIV: DB - Geology ; Mineralogy

  12. Pasco Basin hydrometeorological study

    International Nuclear Information System (INIS)

    This report provides detailed precipitation and evapotranspiration distributions for the Pasco Basin for use in groundwater recharge calculations. The results are shown on precipitation and evapotranspiration distribution maps. The parameters, calculation methods, sensitivity determinations, and fitting methods used in the development of these maps are also discussed

  13. The Mediterranean basin

    DEFF Research Database (Denmark)

    Tomas, Carmen; Sanchez Sanchez, Juan Jose; Barbaro, A.;

    2008-01-01

    genetically from the rest of the populations in the Mediterranean area. This result supports the hypothesis of a low incidence of the south-north genetic interchange at the western shores of the Mediterranean basin. A low genetic distance was found between populations in the Middle East and the western part...

  14. Restoring the Nile Basin

    OpenAIRE

    World Bank Group

    2015-01-01

    Watershed management has come to be recognized as a critical issue in the Nile Basin. Upstream land use can cause degradation and soil erosion, resulting in lower agricultural yields locally and causing sedimentation downstream. The increased sediment load causes economic problems by reducing water quality, and irrigation and hydropower potential, as well as increasing flooding. This note ...

  15. The Importance of Education to Favor the Development of Students’ Creative Ability

    OpenAIRE

    Daniela FLOARES (STOICA)

    2011-01-01

    This study presents the importance of education to favor the development of students' creative ability. The argument insists on the fact that human evolution is conditioned and stimulated by the creativity of individuals and the actual society requires a more rapid accommodation, continuous information conjugation with the inventive creative attitude. In the first part, creativity is the core of the future education in the light of the new curriculum, the relationship between education and cr...

  16. Climate engineering field research: The favorable setting of international environmental law

    OpenAIRE

    Reynolds, J L

    2014-01-01

    As forecasts for climate change and its impacts have become more dire, climate engineering proposals have come under increasing consideration and are presently moving toward field trials. This article examines the relevant international environmental law, distinguishing between climate engineering research and deployment. It also emphasizes the climate change context of these proposals and the enabling function of law. Extant international environmental law generally favors such field tests, ...

  17. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism.

    Science.gov (United States)

    Pfattheicher, Stefan; Schindler, Simon

    2016-01-01

    The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR) to measure seeing profoundness in bullshit statements. The BSR scale contains statements that have a correct syntactic structure and seem to be sound and meaningful on first reading but are actually vacuous. Participants (N = 196; obtained via Amazon Mechanical Turk) rated the profoundness of bullshit statements (using the BSR) and provided favorability ratings of three Democratic (Hillary Clinton, Martin O'Malley, and Bernie Sanders) and three Republican candidates for US president (Ted Cruz, Marco Rubio, and Donald Trump). Participants also completed a measure of political liberalism/conservatism. Results revealed that favorable views of all three Republican candidates were positively related to judging bullshit statements as profound. The smallest correlation was found for Donald Trump. Although we observe a positive association between bullshit and support for the three Democrat candidates, this relationship is both substantively small and statistically insignificant. The general measure of political liberalism/conservatism was also related to judging bullshit statements as profound in that individuals who were more politically conservative had a higher tendency to see profoundness in bullshit statements. Of note, these results were not due to a general tendency among conservatives to see profoundness in everything: Favorable views of Republican candidates and conservatism were not significantly related to profoundness ratings of mundane statements. In contrast, this was the case for Hillary Clinton and Martin O'Malley. Overall, small

  18. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism.

    Directory of Open Access Journals (Sweden)

    Stefan Pfattheicher

    Full Text Available The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR to measure seeing profoundness in bullshit statements. The BSR scale contains statements that have a correct syntactic structure and seem to be sound and meaningful on first reading but are actually vacuous. Participants (N = 196; obtained via Amazon Mechanical Turk rated the profoundness of bullshit statements (using the BSR and provided favorability ratings of three Democratic (Hillary Clinton, Martin O'Malley, and Bernie Sanders and three Republican candidates for US president (Ted Cruz, Marco Rubio, and Donald Trump. Participants also completed a measure of political liberalism/conservatism. Results revealed that favorable views of all three Republican candidates were positively related to judging bullshit statements as profound. The smallest correlation was found for Donald Trump. Although we observe a positive association between bullshit and support for the three Democrat candidates, this relationship is both substantively small and statistically insignificant. The general measure of political liberalism/conservatism was also related to judging bullshit statements as profound in that individuals who were more politically conservative had a higher tendency to see profoundness in bullshit statements. Of note, these results were not due to a general tendency among conservatives to see profoundness in everything: Favorable views of Republican candidates and conservatism were not significantly related to profoundness ratings of mundane statements. In contrast, this was the case for Hillary Clinton and Martin O

  19. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism

    OpenAIRE

    Stefan Pfattheicher; Simon Schindler

    2016-01-01

    The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR) to measure seeing profoundness in bullshit statements. The BSR s...

  20. The tax credit in favor of the renewable energies and the energy savings bear fruits

    International Nuclear Information System (INIS)

    This document presents in the first part the positive economical results obtained by the implementing in January 2005, of a tax credit majored of 40% in favor of equipments using a renewable energy source. The second part is devoted to other financial incentives in the domain of energy saving and renewable energies uses. Specifications concerning the equipments and legal aspects are presented. (A.L.B.)

  1. Improved DNA Electrophoresis in Conditions Favoring Polyborates and Lewis Acid Complexation

    OpenAIRE

    Singhal, Hari; Ren, Yunzhao R.; Kern, Scott E.

    2010-01-01

    Spatial compression among the longer DNA fragments occurs during DNA electrophoresis in agarose and non-agarose gels when using certain ions in the conductive buffer, impairing the range of fragment sizes resolved well in a single gel. Substitutions using various polyhydroxyl anions supported the underlying phenomenon as the complexation of Lewis acids to DNA. We saw significant improvements using conditions (lithium borate 10 mM cations, pH 6.5) favoring the formation of borate polyanions an...

  2. Verification of predictions from estimators of favorable alleles to improve yield of sweet corn hybrids

    OpenAIRE

    Malvar Pintos, Rosa Ana; Revilla Temiño, Pedro; Ordás Pérez, Amando; Cartea González, María Elena; Soengas Fernández, María del Pilar

    2004-01-01

    Sweet corn (Zea mays L.) breeding has focused on quality, with yield and agronomic performance as secondary traits. Elite American and European field corn inbreds were selected to improve the agronomic value of sweet corn for European conditions. Our objective was to compare realized results and predictions of methods to identify potential donors for improving agronomic performance of sweet corn hybrids. Yield and three agronomic traits were recorded. Estimates of favorable dominant alleles p...

  3. Energetically favorable sites of iodine atoms in zirconium crystal: an ab-initio approach

    International Nuclear Information System (INIS)

    This paper is devoted to the determination of the energetically favorable sites of iodine atoms in zirconium crystal within the density functional framework and using norm-conserving pseudopotentials. We show that the substitutional sites are preferentially occupied compared to the interstitial ones. Our conclusion is that the diffusion process of iodine in site zirconium is of substitutional type in perfect agreement with an experimental study. (authors)

  4. Favored subjects and psychosocial needs in music therapy in terminally ill cancer patients: a content analysis

    OpenAIRE

    Preissler, Pia; Kordovan, Sarah; Ullrich, Anneke; Bokemeyer, Carsten; Oechsle, Karin

    2016-01-01

    Background Research has shown positive effects of music therapy on the physical and mental well-being of terminally ill patients. This study aimed to identify favored subjects and psychosocial needs of terminally ill cancer patients during music therapy and associated factors. Methods Forty-one Patients receiving specialized inpatient palliative care prospectively performed a music therapy intervention consisting of at least two sessions (total number of sessions: 166; per patient average: 4,...

  5. Theory Construction in Second Language Acquisition In Favor of the Rationalism

    OpenAIRE

    Mehdi Shokouhi

    2012-01-01

    One of the most controversial issues in second language acquisition (SLA) seems to be the issue of theory construction. There are mainly two opposing views considering the SLA theory construction namely the Rationalist view and the Relativist view. The former tries to reasons that there should be a few theories of SLA at work while the latter favors as many theories as possible. However, the present paper tries to take a supportive stance with regard to the rationalism reasoning that the rati...

  6. Favorable and Unfavorable Characteristics of EFL Teachers Perceived by University Students of Thailand

    OpenAIRE

    Jun Chen

    2012-01-01

    Teachers play pivotal roles in EFL classrooms. Characteristics of EFL teachers may affect students’ attitudes and motivations to language learning. The effective/good characteristics of the EFL teachers perceived by the students have been extensively investigated by the previous research works. However, the perceptions of the students from different backgrounds to EFL teachers may vary in different learning settings. In addition, the research works on both favorable and unfavorable characteri...

  7. Development of a new β Ti alloy with low modulus and favorable plasticity for implant material.

    Science.gov (United States)

    Liang, S X; Feng, X J; Yin, L X; Liu, X Y; Ma, M Z; Liu, R P

    2016-04-01

    One of the most important development directions of the Ti and its alloys is the applications in medical field. Development of new Ti alloys with low elastic modulus and/or favorable biocompatibility plays an important role for promoting its application in medical field. In this work, a new β Ti alloy (Ti-31Nb-6Zr-5Mo, wt.%) was designed for implant material using d-electron alloy design method. Microstructure and tensile properties of the designed alloy after hot rolling (HR) and solution followed by aging treatments (SA) were investigated. Results show that the designed alloy is composed of single β phase. However, microstructural analysis shows that the β phase in the designed alloy separates into Nb-rich and Nb-poor phase regions. The Nb-rich regions in HR specimen are typical elongated fiber texture, but are equiaxed particles with several micrometers in SA specimen. Tensile results show that the designed alloy has low Young's modulus of 44 GPa for HR specimen and 48 GPa for SA specimen which are very close to the extreme of Young's modulus of bulk titanium alloys. At the same time, the designed alloy has favorable plasticity in term of elongation of 26.7% for HR specimen and 20.6% for SA specimen, and appropriate tensile strength over 700 MPa. In short, the designed alloy has low elastic modulus close to that of bone and favorable plasticity and strength which can be a potential candidate for hard tissue replacements. PMID:26838858

  8. The Study of Relationship Between Work Teams and Favoring Knowledge Management (Case: Bank Keshavarzi

    Directory of Open Access Journals (Sweden)

    Hamze Jamshidi Kohsari

    2011-03-01

    Full Text Available Knowledge management is a process that has been recently generated as an activity which isvery important in the dynamic environment, and in the competitive scene. We believe that KM is aprocess which its organizational knowledge is created from the individual knowledge of themembers of the organization. The relevant studies have indicated that organizing based on workteams could be considered a way to create the appropriate context for KM. However, thisorganizing based on work teams is not enough; it only has the necessary characteristics of the workteams that favor KM. Moreover, based on studies done, we distinguish which characteristics ofwork teams favor the KM process in its different phases (i.e. creation, transfer and integration. Inthis study, we conducted multiple regression and analysis of variance.Complementary skills (H2 and a climate of trust (H3 in work teams were more importantfactors that favor the management of organizational knowledge.This research is based on the Zarraga and Perez studies in 2006.

  9. Bransfield Basin and Cordilleran Orogenesis

    Science.gov (United States)

    Dalziel, I. W.; Austin, J. A.; Barker, D. H.; Christensen, G. L.

    2003-12-01

    Tectonic uplift of the Andean Cordillera was initiated in the mid-Cretaceous with inversion of a composite marginal basin along 7500 km of the continental margin of South America, from Peru to Tierra del Fuego and the North Scotia Ridge. In the southernmost Andes, from 50-56 degrees S, the quasi-oceanic floor of this basin is preserved in the obducted ophiolitic rocks of the Rocas Verdes (Green Rocks) basin. We suggest that the basin beneath Bransfield Strait, 61-64 degrees S, separating the South Shetland Islands from the Antarctic Peninsula, constitutes a modern analog for the Rocas Verdes basin. Marine geophysical studies of Bransfield basin have been undertaken over the past 12 years by the Institute for Geophysics, University of Texas at Austin, under the auspices of the Ocean Sciences Division and United States Antarctic Program, National Science Foundation. These studies have elucidated the structure and evolution of Bransfield basin for comparison with the Rocas Verdes basin, with a view to eventual forward modeling of the evolution of a hypothetical cordilleran orogen by compression and inversion of the basin. These are the processes that can be observed in the tectonic transformation of the Rocas Verdes basin into the southernmost Andean cordillera, as South America moved rapidly westward in an Atlantic-Indian ocean hot-spot reference frame during the mid-Cretaceous. Multi-channel reflection seismic data from the Bransfield basin reveal an asymmetric structural architecture characterized by steeply-dipping normal faults flanking the South Shetlands island arc and gently dipping listric normal faults along the Antarctic Peninsula margin. Normal fault polarity reversals appear to be related to distributed loci of magmatic activity within the basin. This architecture is remarkably similar to that deduced from field structural studies of the Rocas Verdes basin. Notably, the oceanward-dipping, low angle normal faults along the Antarctic Peninsula margin

  10. Petroleum exploration potential of Tamtsag Basin

    Institute of Scientific and Technical Information of China (English)

    SUN Guo-qing; GUO Qing-xia; ZHANG Ya-jin; ZHAO Hong-wen

    2004-01-01

    The Tamtsag Basin is located in the extreme eastern portion of the Mongolia. The Basin and its counterpart in China (the Hailar Basin) are united a whole basin on the structural setting. In recent years, the Tamtsag Basin attracts more and more attention with the important exploration discovered in the 19th block by SOCO and in Hailar Basin of China. This paper discusses the exploration potential of Tamtsag Basin from the viewpoint of petroleum geology.

  11. The HII Galaxy Hubble Diagram Strongly Favors Rh = ct over ΛCDM

    Science.gov (United States)

    Wei, Jun-Jie; Wu, Xue-Feng; Melia, Fulvio

    2016-08-01

    We continue to build support for the proposal to use HII galaxies (HIIGx) and giant extragalactic HII regions (GEHR) as standard candles to construct the Hubble diagram at redshifts beyond the current reach of Type Ia supernovae. Using a sample of 25 high-redshift HIIGx, 107 local HIIGx, and 24 GEHR, we confirm that the correlation between the emission-line luminosity and ionized-gas velocity dispersion is a viable luminosity indicator, and use it to test and compare the standard model ΛCDM and the Rh = ct Universe by optimizing the parameters in each cosmology using a maximization of the likelihood function. For the flat ΛCDM model, the best fit is obtained with Ω _m= 0.40_{-0.09}^{+0.09}. However, statistical tools, such as the Akaike (AIC), Kullback (KIC) and Bayes (BIC) Information Criteria favor Rh = ct over the standard model with a likelihood of ≈94.8% - 98.8% versus only ≈1.2% - 5.2%. For wCDM (the version of ΛCDM with a dark-energy equation of state wde ≡ pde/ρde rather than wde = wΛ = -1), a statistically acceptable fit is realized with Ω _m=0.22_{-0.14}^{+0.16} and w_de= -0.51_{-0.25}^{+0.15} which, however, are not fully consistent with their concordance values. In this case, wCDM has two more free parameters than Rh = ct, and is penalized more heavily by these criteria. We find that Rh = ct is strongly favored over wCDM with a likelihood of ≈92.9% - 99.6% versus only 0.4% - 7.1%. The current HIIGx sample is already large enough for the BIC to rule out ΛCDM/wCDM in favor of Rh = ct at a confidence level approaching 3σ.

  12. Sedimentary characteristics of cretaceous in northwestern Ordos basin

    International Nuclear Information System (INIS)

    Based on the integration of previous research achievements and combined with results of field geological investigation, and analysis and determination of samples, as well as the indoor comprehensive study, the paleoclimate characteristics, indications of sedimentary facies, the direction of paleocurrent and the provenance, as well as sedimentary facies and depositional systems of Zhidan Group, Lower Cretaceous in northwestern Ordos basin are systematically analyzed in the framework of the basin evolution. Authors come to a conclusion that sediments of Zhidan Group are mainly of lacustrine and fluvial facies. On the above basis types and features of sand bodies developed in Zhidan Group, Lower Cretaceous are summarized and the potential of uranium ore-formation in different types of sand bodies is discussed.Finally, deltasand bodies of Huachi-Huanhe Formation are thought to be favorable for the formation of sandstone type uranihm deposits. (authors)

  13. Canterbury Basin Sea Level

    OpenAIRE

    Fulthorpe, C. S.; Institute for Geophysics John A. and Katherine G. Jackson School of Geosciences The University of Texas at Austin J.J. Pickle Research Campus, Building 196 (ROC) 10100 Burnet Road (R2200) Austin TX 78758-4445 USA; Hoyanagi, K.; Department of Geology Faculty of Science Shinshu University 3-1-1 Asahi, Matsumoto 390-8621 Japan; Blum, P.; United States Implementing Organization Integrated Ocean Drilling Program Texas A&M University 1000 Discovery Drive College Station TX 77845 USA; Guèrin, G.; Borehole Research Group Lamont-Doherty Earth Observatory of Columbia University PO Box 1000, 61 Route 9W Palisades NY 10964 USA; Slagle, A. L.; Borehole Research Group Lamont-Doherty Earth Observatory of Columbia University PO Box 1000, 61 Route 9W Palisades NY 10964 USA; Blair, S. A.; Department of Geological Sciences Florida State University 006 Carraway Building Tallahassee FL 32306 USA; Browne, G. H.; Hydrocarbon Section GNS Science PO Box 30368 Lower Hutt New Zealand; Carter, R. M.; Marine Geophysical Laboratory James Cook University of North Queensland Townsville QLD 4811 Australia; Ciobanu, M.; Laboratoire de Microbiologie des Environnements Extrêmes CNRS UMR-6197 Institut Universitaire Européen de la Mer Technopole Brest-Iroise Plouzane 29280 France; Claypool, G. E.; Organic Geochemist 8910 West 2nd Avenue Lakewood CO 80226 USA; Crundwell, M. P.; New Zealand Observer/Paleontologist (foraminifers) Paleontology and Environmental Change Section GNS Science PO Box 30368 Lower Hutt New Zealand; Dinarès-Turell, J.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione Roma2, Roma, Italia; Ding, X.; School of Marine Sciences China University of Geosciences (Beijing) 29 XueYuan Road, Haidian District Beijing P.R. China; George, S. C.; Department of Earth and Planetary Sciences Macquarie University Sydney NSW 2109 Australia; Hepp, D. A.; MARUM – Center for Marine Environmental Sciences and Department of Geosciences University of Bremen Leobener Strasse MARUM Building, Room 2230 28359 Bremen Germany

    2010-01-01

    Integrated Ocean Drilling Program (IODP) Expedition 317 was devoted to understanding the relative importance of global sea level (eustasy) versus local tectonic and sedimentary processes in controlling continental margin sedimentary cycles. The expedition recovered sediments from the Eocene to recent period, with a particular focus on the sequence stratigraphy of the late Miocene to recent, when global sea level change was dominated by glacioeustasy. Drilling in the Canterbury Basin,...

  14. Growth and Mycotoxin Production by Chaetomium globosum Is Favored in a Neutral pH

    Directory of Open Access Journals (Sweden)

    Matthew R. Fogle

    2008-11-01

    Full Text Available Chaetomium globosum is frequently isolated in water-damaged buildings and produces two mycotoxins called chaetoglobosins A and C when cultured on building material. In this study, the influence of ambient pH on the growth of C. globosum was examined on an artificial medium. This fungus was capable of growth on potato dextrose agar ranging in pH from 4.3 to 9.4 with optimal growth and chaetoglobosin C production occurring at a neutral pH. In addition, our results show that sporulation is favored in an acidic environment.

  15. Favorable outcome of patients affected by rhabdoid tumors due to rhabdoid tumor predisposition syndrome (RTPS).

    Science.gov (United States)

    Kordes, Uwe; Bartelheim, Kerstin; Modena, Piergiorgio; Massimino, Maura; Biassoni, Veronica; Reinhard, Harald; Hasselblatt, Martin; Schneppenheim, Reinhard; Frühwald, Michael C

    2014-05-01

    Rhabdoid tumor predisposition syndrome is usually associated with shorter survival in patients with malignant rhabdoid tumors regardless of anatomical origin. Here we present four children harboring truncating heterozygous SMARCB1/INI1 germline mutations with favorable outcome. All four patients received multi-modality treatment, three according to therapeutic recommendations by the EU-RHAB registry, two without radiotherapy, and mean event-free survival accounts for 7 years. In conclusion, intensive treatment with curative intent is justified for children with rhabdoid tumors even if an underlying rhabdoid predisposition syndrome is demonstrated. PMID:24123847

  16. Some concepts of favorability for world-class-type uranium deposits in the northeastern United States

    Energy Technology Data Exchange (ETDEWEB)

    Adler, H.H.

    1981-03-01

    An account is given of concepts of favorability of geologic environments in the eastern United States for uranium deposits of several major types existing elsewhere in the world. The purpose is to convey some initial ideas about the interrelationships of the geology of the eastern United States and the geologic settings of certain of these world-class deposits. The study and report include consideration of uranium deposits other than those generally manifesting the geologic, geochemical and genetic characteristics associated with the conventional sandstone-type ores of the western United States.

  17. 2005 winter meeting - pleading in favor of a sensible energy mix

    International Nuclear Information System (INIS)

    The year's Winter Meeting of Deutsches Atomforum, which was held under the general heading of 'Pleading in Favor of a Sensible Energy Mix', dealt with the large variety of aspects and perspectives of this important key topic, also with respect to the sustainability factors, environment, economy, and social aspects. Twelve contributions, or statements, by representatives from politics, industry, society, and research covered different aspects of a 'sensible energy mix'. A round of politicians debated the subject controversially. The meeting, which was attended by more than 250 participants, thus opened 2005 with an interesting presentation of present and future topics of the power supply debate. (orig.)

  18. 2005 DAtF winter meeting - pleading in favor of a sensible energy mix

    International Nuclear Information System (INIS)

    The year's Winter Meeting of Deutsches Atomforum, which was held under the general heading of 'Pleading in Favor of a Sensible Energy Mix', dealt with the large variety of aspects and perspectives of this important key topic, also with respect to the sustainability factors, environment, economy, and social aspects. Twelve contributions, or statements, by representatives from politics, industry, society, and research covered different aspects of a 'sensible energy mix'. A round of politicians debated the subject controversially. The meeting, which was attended by more than 250 participants, thus opened 2005 with an interesting presentation of present and future topics of the power supply debate. (orig.)

  19. Some concepts of favorability for world-class-type uranium deposits in the northeastern United States

    International Nuclear Information System (INIS)

    An account is given of concepts of favorability of geologic environments in the eastern United States for uranium deposits of several major types existing elsewhere in the world. The purpose is to convey some initial ideas about the interrelationships of the geology of the eastern United States and the geologic settings of certain of these world-class deposits. The study and report include consideration of uranium deposits other than those generally manifesting the geologic, geochemical and genetic characteristics associated with the conventional sandstone-type ores of the western United States

  20. Educar a favor d'una nova cultura ambiental de l'aigua

    OpenAIRE

    Castelltort Valls, Alba

    2015-01-01

    Aquesta tesi doctoral és un estudi de casos que té per objectiu identificar i analitzar les condicions i les activitats que contribueixen a la formació d'una nova cultura ambiental de l'aigua en l'alumnat de l'Educació Primària (EP) i en els estudiants del Grau d'Educació Primària (GEP). Entenent per nova cultura ambiental de l'aigua el conjunt de coneixements -tant conceptuals com actitudinals- que han d'afavorir una competència per actuar a favor de la conservació dels recursos hídrics. En ...

  1. IMPACT OF ISLAMIC RELIGIOUS SYMBOL IN PRODUCING FAVORABLE ATTITUDE TOWARD ADVERTISEMENT

    Directory of Open Access Journals (Sweden)

    Abbas NASERI

    2012-06-01

    Full Text Available A review of the literature on religion and advertisement led to the identification of three lines of studies examining the influence of religion on advertising. These three lines of studies focused on attitude toward advertising of controversial products, presence of religious values in advertisements executions, and the consumers’ reactions to advertisement containing religious cues or symbols. The latter line has been followed modestly in Christian context but not in Islamic context of advertising. Hijab as a significant religious cue might peripherally generates a favorable attitude toward advertisement among Muslims. It is suggested that information processing theories like Elaboration Likelihood Model provides a pertinent theoretical framework to examine this effect empirically.

  2. Geochemistry and genesis of heavy oil in the Erlian Basin

    Institute of Scientific and Technical Information of China (English)

    FANG Jie; GU Lianxing

    2005-01-01

    Heavy oil is commonly distributed in the Erlian Basin, North China. It can be divided into two genetic types: the primary and the secondary. Primary heavy oil is generated directly by Cretaceous immature or low-mature hydrocarbon sources, or is derived from differentiation of crude oil during migration. Oil of this type has viscosity vagrees, is resultant from a combination of biodegradation, water-leaching and oxidation of primary heavy oil. Based upon a large number of determinations on the physical properties of crude oil, GC analyses of saturated and aromatic hydrocarbons, and GC-MS analyses of steranes and terpanes, the characteristics of heavy oil of various types have been described. Differences in inspissation degree have made it possible the grouping of heavy oil of the Erlian Basin inspissation, the products vary from common heavy to over-heavy oil. Slope and uplifted areas inside a reservoir basin are most favorable to the inspissation and formation of heavy oil. Interaction of several mechanisms of inspissation has resulted in a widespread distribution of heavy oil within the Erlian Basin.

  3. Control of facies/potential on hydrocarbon accumulation:a geological model for Iacustrine rift basins

    Institute of Scientific and Technical Information of China (English)

    Chen Dongxia; Pang Xiongqi; Zhang Shanwen; Wang Yongshi; Zhang Jun

    2008-01-01

    The formation and distribution of hydrocarbon accumulations are jointly controlled by"stratigraphic facies"and"fluid potential",which can be abbreviated in"control of facies/potential on hydrocarbon accumulation".Facies and potential control the time-space distribution of hydrocarbon accumulation macroscopically and the petroliferous characteristics of hydrocarbon accumulation microscopically.Tectonic facies and sedimentary facies control the time-space distribution.Lithofacies and petrophysical facies control the petroliferous characteristics.Favorable facies and high porosity and permeability control hydrocarbon accumulation in the lacustrine rift basins in China.Fluid potential is represented by the work required,which comprises the work against gravity,pressure,interfacial energy and kinetic energy.Hydrocarbon migration and accumulation are controlled by the joint action of multiple driving forces,and are characterized by accumulation in the area of low potential.At the structural high,low geopotential energy caused by buoyancy control anticlinal reservoir.The formation of lithological oil pool is controlled by low interfacial energy caused by capillary force.Low compressive energy caused by overpressure and faulting activity control the formation of the faulted block reservoir.Low geopotential energy of the basin margin caused by buoyancy control stratigraphic reservoir.The statistics of a large number of oil reservoirs show that favorable facies and low potential control hydrocarbon accumulation in the rift basin.where over 85% of the discovered hydrocarbon accumulations are distributed in the trap with favorable facies and lOW potentials.The case study showed that the prediction of favorable areas by application of the near source-favorable facies-low potential accumulation model correlated well with over 90% of the discovered oil pools' distribution of the middle section of the third member of the Shahejie Formation in the Dongying Depression,Bohai Bay

  4. FAVOR: A new fracture mechanics code for reactor pressure vessels subjected to pressurized thermal shock

    International Nuclear Information System (INIS)

    This report discusses probabilistic fracture mechanics (PFM) analysis which is a major element of the comprehensive probabilistic methodology endorsed by the NRC for evaluation of the integrity of Pressurized Water Reactor (PWR) pressure vessels subjected to pressurized-thermal-shock (PTS) transients. It is anticipated that there will be an increasing need for an improved and validated PTS PFM code which is accepted by the NRC and utilities, as more plants approach the PTS screening criteria and are required to perform plant-specific analyses. The NRC funded Heavy Section Steel Technology (HSST) Program at Oak Ridge National Laboratories is currently developing the FAVOR (Fracture Analysis of Vessels: Oak Ridge) PTS PFM code, which is intended to meet this need. The FAVOR code incorporates the most important features of both OCA-P and VISA-II and contains some new capabilities such as PFM global modeling methodology, the capability to approximate the effects of thermal streaming on circumferential flaws located inside a plume region created by fluid and thermal stratification, a library of stress intensity factor influence coefficients, generated by the NQA-1 certified ABAQUS computer code, for an adequate range of two and three dimensional inside surface flaws, the flexibility to generate a variety of output reports, and user friendliness

  5. Description of electromagnetic and favored $\\alpha$-transitions in heavy odd-mass nuclei

    CERN Document Server

    Dumitrescu, A

    2016-01-01

    We describe electromagnetic and favored \\alpha-transitions to rotational bands in odd-mass nuclei built upon a single particle state with angular momentum projection $\\Omega=\\frac{1}{2}$ in the region $88 \\le Z \\le 98$. We use the particle coupled to an even-even core approach described by the Coherent State Model (CSM) and the coupled channels method to estimate partial $\\alpha$-decay widths. We reproduce the energy levels of the rotational band where favored $\\alpha$-transitions occur for 26 nuclei and predict B (E2) values for electromagnetic transitions to the bandhead using a deformation parameter and a Hamiltonian strength parameter for each nucleus, together with an effective collective charge depending linearly on the deformation parameter. Where experimental data is available, the contribution of the single particle effective charge to the total B (E2) value is calculated. The Hamiltonian describing the $\\alpha$- nucleus interaction contains two terms, a spherically symmetric potential given by the d...

  6. Bond population analysis on combination of favorable growth unit of Al(OH)3 crystals

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The quantum chemical calculation on four representative combination modes of the favorable growth unit Al6(OH)18(H2O)6of Al(OH)3 crystals and the single unit were calculated. On the base of the prior investigation, and from the point of view of bond population and net atomic charge, the relationships between the combination mode of the favorable growth unit and the relative intensity of chemical bond of the systems were discussed. The quantum chemistry calculations were performed at RB3LYP/6-31G and RHF/6-31G levels by ab initio and DFT methods respectively. From the point of view of bond population, it can be preliminarily presumed that the interatomic bond force of the system with side-face-combination-B mode is weaker to a certain extent. From the point of view of the net charge, when the combination mode is obverse-face-combination-D, the interatomic bond force will be enhanced.

  7. Bound on the Slope of Steady Water Waves with Favorable Vorticity

    Science.gov (United States)

    Strauss, Walter A.; Wheeler, Miles H.

    2016-07-01

    We consider the angle {θ} of inclination (with respect to the horizontal) of the profile of a steady two dimensional inviscid symmetric periodic or solitary water wave subject to gravity. Although {θ} may surpass 30° for some irrotational waves close to the extreme wave, Amick (Arch Ration Mech Anal 99(2):91-114, 1987) proved that for any irrotational wave the angle must be less than 31.15°. Is the situation similar for periodic or solitary waves that are not irrotational? The extreme Gerstner wave has infinite depth, adverse vorticity and vertical cusps (θ = 90°). Moreover, numerical calculations show that even waves of finite depth can overturn if the vorticity is adverse. In this paper, on the other hand, we prove an upper bound of 45° on {θ} for a large class of waves with favorable vorticity and finite depth. In particular, the vorticity can be any constant with the favorable sign. We also prove a series of general inequalities on the pressure within the fluid, including the fact that any overturning wave must have a pressure sink.

  8. 8 CFR 316.11 - Attachment to the Constitution; favorable disposition towards the good order and happiness.

    Science.gov (United States)

    2010-01-01

    ... disposition towards the good order and happiness. 316.11 Section 316.11 Aliens and Nationality DEPARTMENT OF... the Constitution; favorable disposition towards the good order and happiness. (a) General. An... favorably disposed toward the good order and happiness of the United States. Attachment implies a depth...

  9. Gas hydrate formation and accumulation potential in the Qiangtang Basin, northern Tibet, China

    International Nuclear Information System (INIS)

    Highlights: • Qiangtang Basin is the biggest residual petroleum-bearing basin in Tibet Plateau. • The Late Triassic Tumen Gela Formation is the most important gas source rock. • Seventy-one potential anticline structural traps have been found. • A favorable geothermal condition for gas hydrate formation. • A large number of mud volcanoes were discovered in the basin. - Abstract: The Qiangtang Basin is the biggest residual petroleum-bearing basin in the Qinghai–Tibet Plateau, and is also an area of continuous permafrost in southwest China with strong similarities to other known gas-hydrate-bearing regions. Permafrost thickness is typically 60–180 m; average surface temperature ranges from −0.2 to −4.0 °C, and the geothermal gradient is about 2.64 °C/100 m. In the basin, the Late Triassic Tumen Gela Formation is the most important gas source rock for gas, and there are 34.3 × 108 t of gas resources in the Tumen Gela Formation hydrocarbon system. Seventy-one potential anticline structural traps have been found nowadays covering an area of more than 30 km2 for each individual one, five of them are connected with the gas source by faults. Recently, a large number of mud volcanoes were discovered in the central Qiangtang Basin, which could be indicative of the formation of potential gas hydrate. The North Qiangtang depression should be delineated as the main targets for the purpose of gas hydrate exploration

  10. Effects of basin bottom slope on jet hydrodynamics and river mouth bar formation

    Science.gov (United States)

    Jiménez-Robles, A. M.; Ortega-Sánchez, M.; Losada, M. A.

    2016-06-01

    River mouth bars are strategic morphological units primarily responsible for the development of entire deltaic systems. This paper addresses the role of receiving basin slope in the hydrodynamics of an exiting sediment-laden turbulent jet and in resulting mouth bar morphodynamics. We use Delft3D, a coupled hydrodynamic and morphodynamic numerical model, along with a theoretical formulation to reproduce the physics of the problem, characterized by a fluvially dominated inlet free of waves and tides. We propose an updated theoretical model with a slope-dependent entrainment coefficient, showing that the rate at which ambient fluid is incorporated into a jet increases with higher basin slopes. Transient results reveal that the magnitude of a basin slope can alter the stability of a jet, favoring the formation of an unstable meandering jet. While a stable jet gives rise to "middle-ground" bars accompanied by diverging channels, a "lunate" mouth bar results from unstable jets. Additional morphodynamic simulations demonstrate that the time required for mouth bar stagnation in its final position increases linearly with the basin slope. In contrast, the distance at which the mouth bar eventually forms decreases until reaching an asymptotic value for slopes higher than 2%. Moreover, the basin slope highly influences sedimentary processes responsible for bar formation: for milder slopes, progradation processes prevail, while in steeper basins aggradation is more relevant. Finally, the minimum relative water depth over a bar crest that forces the flow to bifurcate around a fully developed bar decreases with the basin slope.

  11. Intracontinental basins and strong earthquakes

    Institute of Scientific and Technical Information of China (English)

    邓起东; 高孟潭; 赵新平; 吴建春

    2004-01-01

    The September 17, 1303 Hongtong M=8 earthquake occurred in Linfen basin of Shanxi down-faulted basin zone. It is the first recorded M=8 earthquake since the Chinese historical seismic records had started and is a great earthquake occurring in the active intracontinental basin. We had held a Meeting of the 700th Anniversary of the 1303 Hongtong M=8 Earthquake in Shanxi and a Symposium on Intracontinental Basins and Strong Earthquakes in Taiyuan City of Shanxi Province on September 17~18, 2003. The articles presented on the symposium discussed the relationships between active intracontinental basins of different properties, developed in different regions, including tensional graben and semi-graben basins in tensile tectonic regions, compression-depression basins and foreland basins in compressive tectonic regions and pull-apart basins in strike-slip tectonic zones, and strong earthquakes in China. In this article we make a brief summary of some problems. The articles published in this special issue are a part of the articles presented on the symposium.

  12. Multiple oscillatory modes of the Argentine Basin. Part II. The spectral origin of the basin modes

    NARCIS (Netherlands)

    Weijer, W.; Vevier, F.; Gille, S.T.; Dijkstra, H.A.

    2007-01-01

    In this paper the spectrum of barotropic basin modes of the Argentine Basin is shown to be connected to the classical Rossby basin modes of a flat-bottom (constant depth), rectangular basin. First, the spectrum of basin modes is calculated for the Argentine Basin, by performing a normal-mode analysi

  13. Some effects of favorable and adverse electric fields on pool boiling in dielectric fluids

    International Nuclear Information System (INIS)

    The effects of the application of an electric field on pool boiling in dielectric fluids were studied in this work.Two different geometries were used: one which is favorable to the bubble detachment (favorable electric field) and other which attract the bubbles toward the heater (adverse electric field).In the favorable electric field experiments, the void fraction and impact rate were calculated from the measured indicator function.Those parameters were obtained varying the probe-heater distance and the power to the heater.The results show a reduction of the void fraction with increasing applied voltage, probably caused by the combination of the dielectrophoretic force and a smaller bubble size due to the electric field application. Also, the impact rate decreases when a voltage is applied and the heat fluxes are close to the critical heat flux (CHF).On the other hand, the impact rate increases with voltage for moderate heat fluxes.Another interesting result is the approximately exponential decay of the void fraction and impact rate with the distance to the heater. Both the void fraction and the impact rate grow with heat flux if the heat fluxes are moderate, with or without applied voltage.For highest heat fluxes the void fraction still grows with heat flux if there are no applied electric fields while decreases with heat flux when there is an applied voltage. Similar behavior is observed in the impact rate.The boiling regimes was measured with adverse electric fields using two techniques.The heat transfer in the nucleate boiling regime was measured on an electrically powered heater.The results in these experiments show a reduction in the CHF of 10 % for saturation conditions and 10 kV of applied voltage, and a reduction of up to 40 % for 20 oC of liquid subcooling.The boiling curve corresponding to the transition and film boiling was performed with quenching experiments.An increase in the heat flux was achieved when an electric field was applied in spite of the

  14. Meso-Cenozoic tectonic evolution and uranium potential evaluations of basins in Beishan-Gansu corridor region

    International Nuclear Information System (INIS)

    Beishan-Gansu Corridor region is located at the intersection of the plates of Tarim, North China, Kazakhstan, Siberia and Qaidam. During the Meso-Cenozoic, the region experienced movements of Indo-sinian, Yanshanian, Sichuanian, North China, Himalayan and Neotectonic, and over 20 medium-small size superimposed continental basins were formed. On the basis of analyzing the tectonic stress field, sediment-filling and structure-deformation; the general trending of tectonic evolution in the Meso-Cenozoic is summarized as three-time compressional uplifting and two-time extensional down-faulting. The different evolution of basins under the above mentioned setting can be divided into six stages according to characteristics of filled sediment. The sand bodies developed in down-faulted basins are favorable for uranium ore-formation as they are formed under humid paleoclimates, and rich in reducing matter. Therefore, the Lower-Middle Jurassic is selected as the main target horizon for sandstone-hosted uranium deposit, and the Lower Cretaceous as the minor one. Although the tectonic reactivation of the target horizon after its deposition was generally strong, the slopes formed in some basins could be favorable for the infiltration of uranium-and oxygen-bearing groundwater into sand bodies and form uranium deposits. According to the favorable sand bodies and tectonic reactivation, the northern parts of Chaoshui and Bayingobi basins are regarded as potential regions which are worthy of further exploration. (authors)

  15. Teaching accreditation exams reveal grading biases favor women in male-dominated disciplines in France.

    Science.gov (United States)

    Breda, Thomas; Hillion, Mélina

    2016-07-29

    Discrimination against women is seen as one of the possible causes behind their underrepresentation in certain STEM (science, technology, engineering, and mathematics) subjects. We show that this is not the case for the competitive exams used to recruit almost all French secondary and postsecondary teachers and professors. Comparisons of oral non-gender-blind tests with written gender-blind tests for about 100,000 individuals observed in 11 different fields over the period 2006-2013 reveal a bias in favor of women that is strongly increasing with the extent of a field's male-domination. This bias turns from 3 to 5 percentile ranks for men in literature and foreign languages to about 10 percentile ranks for women in math, physics, or philosophy. These findings have implications for the debate over what interventions are appropriate to increase the representation of women in fields in which they are currently underrepresented. PMID:27471301

  16. Cosmology Favoring Extra Radiation and Sub-eV Mass Sterile Neutrinos as an Option

    International Nuclear Information System (INIS)

    Precision cosmology and big-bang nucleosynthesis mildly favor extra radiation in the Universe beyond photons and ordinary neutrinos, lending support to the existence of low-mass sterile neutrinos. We use the WMAP 7-year data, small-scale cosmic microwave background observations from ACBAR, BICEP, and QuAD, the SDSS 7th data release, and measurement of the Hubble parameter from HST observations to derive credible regions for the assumed common mass scale ms and effective number Ns of thermally excited sterile neutrino states. Our results are compatible with the existence of one or perhaps two sterile neutrinos, as suggested by LSND and MiniBooNE, if ms is in the sub-eV range.

  17. How to Ask for a Favor: A Case Study on the Success of Altruistic Requests

    CERN Document Server

    Althoff, Tim; Jurafsky, Dan

    2014-01-01

    Requests are at the core of many social media systems such as question & answer sites and online philanthropy communities. While the success of such requests is critical to the success of the community, the factors that lead community members to satisfy a request are largely unknown. Success of a request depends on factors like who is asking, how they are asking, when are they asking, and most critically what is being requested, ranging from small favors to substantial monetary donations. We present a case study of altruistic requests in an online community where all requests ask for the very same contribution and do not offer anything tangible in return, allowing us to disentangle what is requested from textual and social factors. Drawing from social psychology literature, we extract high-level social features from text that operationalize social relations between recipient and donor and demonstrate that these extracted relations are predictive of success. More specifically, we find that clearly communic...

  18. Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres.

    Science.gov (United States)

    Schnerch, D; Nigg, E A

    2016-05-01

    Structural centrosome aberrations are frequently observed in early stage carcinomas, but their role in malignant transformation is poorly understood. Here, we examined the impact of overexpression of Ninein-like protein (Nlp) on the architecture of polarized epithelia in three-dimensional mammospheres. When Nlp was overexpressed to levels resembling those seen in human tumors, it formed striking centrosome-related bodies (CRBs), which sequestered Ninein and affected the kinetics of microtubule (MT) nucleation and release. In turn, the profound reorganization of the MT cytoskeleton resulted in mislocalization of several adhesion and junction proteins as well as the tumor suppressor Scribble, resulting in the disruption of epithelial polarity, cell-cell interactions and mammosphere architecture. Remarkably, cells harboring Nlp-CRBs displayed an enhanced proliferative response to epidermal growth factor. These results demonstrate that structural centrosome aberrations cause not only the disruption of epithelial polarity but also favor overproliferation, two phenotypes typically associated with human carcinomas. PMID:26364601

  19. Maternal Acceptance: Its Contribution to Children's Favorable Perceptions of Discipline and Moral Identity.

    Science.gov (United States)

    Patrick, Renee B; Gibbs, John C

    2016-01-01

    The authors examined the contribution of maternal acceptance or warmth to children's and adolescents' perceptions of discipline and formation of moral identity. The sample consisted of 93 male and female students from Grades 5, 8, and 10 and their mothers. Students completed measures pertaining to perceived maternal discipline practices and acceptance-rejection, as well as moral identity. A subsample of mothers reported on their accepting or rejecting actions toward their children. Children were more likely to feel accepted, if their mothers used inductive discipline (vs. power assertion and love withdrawal). Perceived acceptance was also related to more favorable discipline evaluations in certain respects. Specifically, inductive discipline recipients who felt accepted also evaluated induction as appropriate and responded to it with positive and guilt-related emotions. Power assertion was evaluated as appropriate among those children who did feel accepted. Finally, among inductive discipline recipients, those who felt accepted also reported higher moral identity. PMID:27177121

  20. Intramolecular Crystal Nucleation Favored by Polymer Crystallization: Monte Carlo Simulation Evidence.

    Science.gov (United States)

    Zhang, Rong; Zha, Liyun; Hu, Wenbing

    2016-07-14

    We performed dynamic Monte Carlo simulations of half-half binary blends of symmetric (double and mutual) crystallizable polymers. We separately enhanced the driving forces for polymer-uniform and polymer-staggered crystals. Under parallel enhancements, polymer-uniform crystals exhibit faster nucleation and growth, with more chain folding and less lamellar thickening, than those in polymer-staggered crystals. We attributed the results to intramolecular crystal nucleation, ruined by enhanced polymer-staggered crystallization. Our observations provide direct molecular-level evidence to support the fact that intramolecular crystal nucleation is favored by polymer crystallization in quiescent solutions and melt, which yields chain folding for the characteristic β-sheet or lamellar morphology of macromolecular crystals. PMID:27300471

  1. Balanced bilinguals favor lexical processing in their opaque language and conversion system in their shallow language.

    Science.gov (United States)

    Buetler, Karin A; de León Rodríguez, Diego; Laganaro, Marina; Müri, René; Nyffeler, Thomas; Spierer, Lucas; Annoni, Jean-Marie

    2015-11-01

    Referred to as orthographic depth, the degree of consistency of grapheme/phoneme correspondences varies across languages from high in shallow orthographies to low in deep orthographies. The present study investigates the impact of orthographic depth on reading route by analyzing evoked potentials to words in a deep (French) and shallow (German) language presented to highly proficient bilinguals. ERP analyses to German and French words revealed significant topographic modulations 240-280 ms post-stimulus onset, indicative of distinct brain networks engaged in reading over this time window. Source estimations revealed that these effects stemmed from modulations of left insular, inferior frontal and dorsolateral regions (German>French) previously associated to phonological processing. Our results show that reading in a shallow language was associated to a stronger engagement of phonological pathways than reading in a deep language. Thus, the lexical pathways favored in word reading are reinforced by phonological networks more strongly in the shallow than deep orthography. PMID:26545236

  2. Evaluating Environmental Favorability for Tropical Cyclone Development with the Method of Point-Downscaling

    Directory of Open Access Journals (Sweden)

    David S Nolan

    2011-08-01

    Full Text Available A new method is presented to determine the favorability for tropical cyclone development of an atmospheric environment, as represented by a mean sounding of temperature, humidity, and wind as a function of height. A mesoscale model with nested, moving grids is used to simulate the evolution of a weak, precursor vortex in a large domain with doubly periodic boundary conditions. The equations of motion are modified to maintain arbitrary profiles of both zonal and meridional wind as a function of height, without the necessary large-scale temperature gradients that cannot be consistent with doubly periodic boundary conditions. Comparisons between simulations using the point-downscaling method and simulations using wind shear balanced by temperature gradients illustrate both the advantages and the limitations of the technique. Further examples of what can be learned with this method are presented using both idealized and observed soundings and wind profiles.

  3. Apollo Basin, Moon: Estimation of Impact Conditions

    Science.gov (United States)

    Echaurren, J. C.

    2015-07-01

    The Apollo Basin is a, pre-Nectarian, multi-ring basin located within the large South Pole-Aitken Basin (SPA). Multispectral data from both Galileo and Clementine showed that the composition of materials in Apollo is distinct…

  4. FAVOR: A new fracture mechanics code for reactor pressure vessels subjected to pressurized thermal shock

    International Nuclear Information System (INIS)

    Probabilistic fracture mechanics (PFM) analysis is a major element of the comprehensive probabilistic methodology endorsed by the Nuclear Regulatory Commission (NRC) for evaluation of the integrity of pressurized water reactor pressure vessels subjected to pressurized-thermal-shock (PTS) transients. OCA-P and VISA-II are PTS PFM computer codes that are currently referenced in Regulatory Guide 1.154 as acceptable codes for performing plant-specific analyses. These codes perform PFM analyses to estimate the increase in vessel failure probability as the vessel accumulates radiation damage over the operating life of the vessel. Experience with the application of these codes in the last few years has provided insights into areas where they could be improved. As more plants approach the PTS screening criteria and are required to perform plant-specific analyses, there will be an increasing need for an improved and validated PTS PFM code that is accepted by the NRC and utilities. The NRC funded Heavy Section Steel Technology Program (HSST) at the Oak Ridge National Laboratory is currently developing the FAVOR (Fracture Analysis of Vessels: Oak Ridge) code, which is expected to meet this need. The FAVOR code incorporates the most important features of both OCA-P and VISA-II and contains some new capabilities such as (1) a PFM global modeling methodology; (2) the calculation of the axial stress component associated with coolant streaming beneath an inlet nozzle; (3) a library of stress intensity factor influence coefficients, generated by the NQA-1 certified ABAQUS computer code, for an appropriate range of two and three dimensional inner-surface flaws; (4) the flexibility to generate a variety of output reports; and (5) enhanced user friendliness

  5. Orai1 Expression Is Closely Related with Favorable Prognostic Factors in Clear Cell Renal Cell Carcinoma.

    Science.gov (United States)

    Lkhagvadorj, Sayamaa; Kim, Ji-Hee; Oh, Sung-Soo; Lee, Mi-Ra; Jung, Jae Hung; Chung, Hyun Chul; Cha, Seung-Kuy; Eom, Minseob

    2016-06-01

    Store-operated calcium (Ca(2+)) entry (SOCE) is the principal Ca(2+) entry route in non-excitable cells, including cancer cells. We previously demonstrated that Orai1 and STIM1, the molecular components of SOCE, are involved in tumorigenesis of clear cell renal cell carcinoma (CCRCC). However, a clinical relevance of Orai1 and STIM1 expression in CCRCC has been ill-defined. Here, we investigated the expression of Orai1 and STIM1 in CCRCC, and compared their expression with clinico-pathological parameters of CCRCC and the patients' outcome. Immunohistochemical staining for Orai1 and STIM1 was performed on 126 formalin fixed paraffin embedded tissue of CCRCC and western blot analysis for Orai1 was performed on the available fresh tissue. The results were compared with generally well-established clinicopathologic prognostic factors in CCRCC and patient survival. Membrane protein Orai1 is expressed in the nuclei in CCRCC, whereas STIM1 shows the cytosolic expression pattern in immunohistochemical staining. Orai1 expression level is inversely correlated with CCRCC tumor grade, whereas STIM1 expression level is not associated with tumor grade. The higher Orai1 expression is significantly associated with lower Fuhrman nuclear grade, pathologic T stage, and TNM stage and with favorable prognosis. The expression level of STIM1 is not correlated with CCRCC grade and clinical outcomes. Orai1 expression in CCRCC is associated with tumor progression and with favorable prognostic factors. These results suggest that Orai1 is an attractive prognostic marker and therapeutic target for CCRCC. PMID:27247496

  6. Does community-based conservation shape favorable attitudes among locals? an empirical study from nepal.

    Science.gov (United States)

    Mehta, J N; Heinen, J T

    2001-08-01

    Like many developing countries, Nepal has adopted a community-based conservation (CBC) approach in recent years to manage its protected areas mainly in response to poor park-people relations. Among other things, under this approach the government has created new "people-oriented" conservation areas, formed and devolved legal authority to grassroots-level institutions to manage local resources, fostered infrastructure development, promoted tourism, and provided income-generating trainings to local people. Of interest to policy-makers and resource managers in Nepal and worldwide is whether this approach to conservation leads to improved attitudes on the part of local people. It is also important to know if personal costs and benefits associated with various intervention programs, and socioeconomic and demographic characteristics influence these attitudes. We explore these questions by looking at the experiences in Annapurna and Makalu-Barun Conservation Areas, Nepal, which have largely adopted a CBC approach in policy formulation, planning, and management. The research was conducted during 1996 and 1997; the data collection methods included random household questionnaire surveys, informal interviews, and review of official records and published literature. The results indicated that the majority of local people held favorable attitudes toward these conservation areas. Logistic regression results revealed that participation in training, benefit from tourism, wildlife depredation issue, ethnicity, gender, and education level were the significant predictors of local attitudes in one or the other conservation area. We conclude that the CBC approach has potential to shape favorable local attitudes and that these attitudes will be mediated by some personal attributes. PMID:11443381

  7. High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor.

    Directory of Open Access Journals (Sweden)

    Raoul A Droeser

    Full Text Available BACKGROUND: Colorectal cancer (CRC infiltration by adaptive immune system cells correlates with favorable prognosis. The role of the innate immune system is still debated. Here we addressed the prognostic impact of CRC infiltration by neutrophil granulocytes (NG. METHODS: A TMA including healthy mucosa and clinically annotated CRC specimens (n = 1491 was stained with MPO and CD15 specific antibodies. MPO+ and CD15+ positive immune cells were counted by three independent observers. Phenotypic profiles of CRC infiltrating MPO+ and CD15+ cells were validated by flow cytometry on cell suspensions derived from enzymatically digested surgical specimens. Survival analysis was performed by splitting randomized data in training and validation subsets. RESULTS: MPO+ and CD15+ cell infiltration were significantly correlated (p<0.0001; r = 0.76. However, only high density of MPO+ cell infiltration was associated with significantly improved survival in training (P = 0.038 and validation (P = 0.002 sets. In multivariate analysis including T and N stage, vascular invasion, tumor border configuration and microsatellite instability status, MPO+ cell infiltration proved an independent prognostic marker overall (P = 0.004; HR = 0.65; CI:±0.15 and in both training (P = 0.048 and validation (P = 0.036 sets. Flow-cytometry analysis of CRC cell suspensions derived from clinical specimens showed that while MPO+ cells were largely CD15+/CD66b+, sizeable percentages of CD15+ and CD66b+ cells were MPO-. CONCLUSIONS: High density MPO+ cell infiltration is a novel independent favorable prognostic factor in CRC.

  8. Advanced Chemistry Basins Model

    Energy Technology Data Exchange (ETDEWEB)

    Blanco, Mario; Cathles, Lawrence; Manhardt, Paul; Meulbroek, Peter; Tang, Yongchun

    2003-02-13

    The objective of this project is to: (1) Develop a database of additional and better maturity indicators for paleo-heat flow calibration; (2) Develop maturation models capable of predicting the chemical composition of hydrocarbons produced by a specific kerogen as a function of maturity, heating rate, etc.; assemble a compositional kinetic database of representative kerogens; (3) Develop a 4 phase equation of state-flash model that can define the physical properties (viscosity, density, etc.) of the products of kerogen maturation, and phase transitions that occur along secondary migration pathways; (4) Build a conventional basin model and incorporate new maturity indicators and data bases in a user-friendly way; (5) Develop an algorithm which combines the volume change and viscosities of the compositional maturation model to predict the chemistry of the hydrocarbons that will be expelled from the kerogen to the secondary migration pathways; (6) Develop an algorithm that predicts the flow of hydrocarbons along secondary migration pathways, accounts for mixing of miscible hydrocarbon components along the pathway, and calculates the phase fractionation that will occur as the hydrocarbons move upward down the geothermal and fluid pressure gradients in the basin; and (7) Integrate the above components into a functional model implemented on a PC or low cost workstation.

  9. Atlantic Basin refining profitability

    International Nuclear Information System (INIS)

    A review of the profitability margins of oil refining in the Atlantic Basin was presented. Petroleum refiners face the continuous challenge of balancing supply with demand. It would appear that the profitability margins in the Atlantic Basin will increase significantly in the near future because of shrinking supply surpluses. Refinery capacity utilization has reached higher levels than ever before. The American Petroleum Institute reported that in August 1997, U.S. refineries used 99 per cent of their capacity for several weeks in a row. U.S. gasoline inventories have also declined as the industry has focused on reducing capital costs. This is further evidence that supply and demand are tightly balanced. Some of the reasons for tightening supplies were reviewed. It was predicted that U.S. gasoline demand will continue to grow in the near future. Gasoline demand has not declined as expected because new vehicles are not any more fuel efficient today than they were a decade ago. Although federally-mandated fuel efficiency standards were designed to lower gasoline consumption, they may actually have prevented consumption from falling. Atlantic margins were predicted to continue moving up because of the supply and demand evidence: high capacity utilization rates, low operating inventories, limited capacity addition resulting from lower capital spending, continued U.S. gasoline demand growth, and steady total oil demand growth. 11 figs

  10. Favorable prognostic value of SOCS2 and IGF-I in breast cancer

    International Nuclear Information System (INIS)

    Suppressor of cytokine signaling (SOCS) proteins comprise a protein family, which has initially been described as STAT induced inhibitors of the Jak/Stat pathway. Recent in vivo and in vitro studies suggest that SOCS proteins are also implicated in cancer. The STAT5 induced IGF-I acts as an endocrine and para/autocrine growth and differentiation factor in mammary gland development. Whereas high levels of circulating IGF-I have been associated with increased cancer risk, the role of autocrine acting IGF-I is less clear. The present study is aimed to elucidate the clinicopathological features associated with SOCS1, SOCS2, SOCS3, CIS and IGF-I expression in breast cancer. We determined the mRNA expression levels of SOCS1, SOCS2, SOCS3, CIS and IGF-I in 89 primary breast cancers by reverse transcriptase PCR. SOCS2 protein expression was further evaluated by immuno-blot and immunohistochemistry. SOCS2 expression inversely correlated with histopathological grade and ER positive tumors exhibited higher SOCS2 levels. Patients with high SOCS2 expression lived significantly longer (108.7 vs. 77.7 months; P = 0.015) and high SOCS2 expression proved to be an independent predictor for good prognosis (HR = 0.45, 95% CI 0.23 – 0.91, P = 0.026). In analogy to SOCS2, high IGF-I expression was an independent predictor for good prognosis in the entire patient cohort. In the subgroup of patients with lymph-node negative disease, high IGF-I was a strong predictor for favorable outcome in terms of overall survival and relapse free survival (HR = 0.075, 95% CI 0.014 – 0.388, P = 0.002). This is the first report on the favorable prognostic value of high SOCS2 expression in primary mammary carcinomas. Furthermore a strong association of high IGF-I expression levels with good prognosis was observed especially in lymph-node negative patients. Our results suggest that high expression of the STAT5 target genes SOCS2 and IGF-I is a feature of differentiated and less malignant tumors

  11. Favorable prognostic value of SOCS2 and IGF-I in breast cancer

    Directory of Open Access Journals (Sweden)

    Daxenbichler Günter

    2007-07-01

    Full Text Available Abstract Background Suppressor of cytokine signaling (SOCS proteins comprise a protein family, which has initially been described as STAT induced inhibitors of the Jak/Stat pathway. Recent in vivo and in vitro studies suggest that SOCS proteins are also implicated in cancer. The STAT5 induced IGF-I acts as an endocrine and para/autocrine growth and differentiation factor in mammary gland development. Whereas high levels of circulating IGF-I have been associated with increased cancer risk, the role of autocrine acting IGF-I is less clear. The present study is aimed to elucidate the clinicopathological features associated with SOCS1, SOCS2, SOCS3, CIS and IGF-I expression in breast cancer. Methods We determined the mRNA expression levels of SOCS1, SOCS2, SOCS3, CIS and IGF-I in 89 primary breast cancers by reverse transcriptase PCR. SOCS2 protein expression was further evaluated by immuno-blot and immunohistochemistry. Results SOCS2 expression inversely correlated with histopathological grade and ER positive tumors exhibited higher SOCS2 levels. Patients with high SOCS2 expression lived significantly longer (108.7 vs. 77.7 months; P = 0.015 and high SOCS2 expression proved to be an independent predictor for good prognosis (HR = 0.45, 95% CI 0.23 – 0.91, P = 0.026. In analogy to SOCS2, high IGF-I expression was an independent predictor for good prognosis in the entire patient cohort. In the subgroup of patients with lymph-node negative disease, high IGF-I was a strong predictor for favorable outcome in terms of overall survival and relapse free survival (HR = 0.075, 95% CI 0.014 – 0.388, P = 0.002. Conclusion This is the first report on the favorable prognostic value of high SOCS2 expression in primary mammary carcinomas. Furthermore a strong association of high IGF-I expression levels with good prognosis was observed especially in lymph-node negative patients. Our results suggest that high expression of the STAT5 target genes SOCS2 and IGF

  12. Typical synoptic situations and their impacts on the wintertime air pollution in the Guanzhong basin, China

    Science.gov (United States)

    Bei, Naifang; Li, Guohui; Huang, Ru-Jin; Cao, Junji; Meng, Ning; Feng, Tian; Liu, Suixin; Zhang, Ting; Zhang, Qiang; Molina, Luisa T.

    2016-06-01

    Rapid industrialization and urbanization have caused severe air pollution in the Guanzhong basin, northwestern China, with heavy haze events occurring frequently in recent winters. Using the NCEP reanalysis data, the large-scale synoptic situations influencing the Guanzhong basin during wintertime of 2013 are categorized into six types to evaluate the contribution of synoptic situations to the air pollution, including "north-low", "southwest-trough", "southeast-high", "transition", "southeast-trough", and "inland-high". The FLEXPART model has been utilized to demonstrate the corresponding pollutant transport patterns for the typical synoptic situations in the basin. Except for "southwest-trough" and "southeast-high" (defined as favorable synoptic situations), the other four synoptic conditions (defined as unfavorable synoptic situations) generally facilitate the accumulation of air pollutants, causing heavy air pollution in the basin. In association with the measurement of PM2.5 (particulate matter with aerodynamic diameter less than 2.5 µm) in the basin, the unfavorable synoptic situations correspond to high PM2.5 mass concentrations or poor air quality and vice versa. The same analysis has also been applied to winters of 2008-2012, which shows that the basin was mainly influenced by the unfavorable synoptic situations during wintertime leading to poor air quality. The WRF-CHEM model has further been applied to simulate the selected 6 days representing the typical synoptic situations during the wintertime of 2013, and the results generally show a good agreement between the modeled distributions and variations of PM2.5 and the corresponding synoptic situations, demonstrating reasonable classification for the synoptic situations in the basin. Detailed meteorological conditions, such as temperature inversion, low-level horizontal wind speed, and planetary boundary layer, all contribute to heavy air pollution events in the basin under unfavorable synoptic conditions

  13. [Gitelman syndrome in pregnancy--a severe hypokalemia with favorable perinatal prognosis].

    Science.gov (United States)

    Rušavý, Z; Hudec, A; Karbanová, J; Korečko, V; Janů, R; Kališ, V

    2012-10-01

    Gitelman syndrom is a rare congenital tubulopathy characterized by hypokalemia, hypomagnesemia, metabolic alkalosis and hypocalciuria. We report a case of a 32-year-old patient admitted for asymptomatic hypokalemia and hypomagnesemia in the 30th week of gestation. A diagnosis of Gitelman syndrom was made and intravenous administration of potassium chloride in high doses combined with spironolactone was started. Despite intensive potassium supplementation (8 g/day), the serum potassium levels remained at the lower limit of normality throughout the pregnancy. The patient delivered a healthy female 2670 g/48 cm after labor induction in the 39th week of gestation. A summary of 22 so far published cases of Gitelman syndrome in pregnancy is presented. The analysis of published case studies suggests a need for ion supplementation, reduction of urinary potassium wasting, monitoring of fetal well-being and amniotic fluid levels. Pregnancy has a very favorable perinatal prognosis despite critical serum levels of potassium and magnesium throughout the pregnancy. PMID:23116347

  14. Superstition predicts favorable weight change in an open-placebo trial: a prospective study.

    Science.gov (United States)

    Rekhviashvili, Nino; Gupta, Sumati

    2015-09-01

    Given the difficulty of losing weight via adhering to healthy lifestyle choices, this study sought to understand how a placebo may elicit favorable weight change. Specifically, we examined if superstition may be related to increased responsiveness to an open-placebo. In this pilot study of 25 undergraduate participants, it was hypothesized that individuals with higher levels of superstition may be more responsive to a 3-week open-placebo weight change trial. Participants were given once-daily saltine crackers to use as open-placebos for weight change in their preferred direction (gain or loss). The weight of each participant was measured before and after the 3-week open-placebo period. A Pearson's r correlation showed a significant positive relationship between superstition and placebo responsiveness, determined by weight gain or loss in the preferred direction, r (25) = 0.493, p < 0.05. We hope these preliminary results engender future research on open-placebo uses for weight management. PMID:25416546

  15. Natural History of Untreated Prostate Specific Antigen Radiorecurrent Prostate Cancer in Men with Favorable Prognostic Indicators

    Directory of Open Access Journals (Sweden)

    Neil E. Martin

    2014-01-01

    Full Text Available Background and Purpose. Life expectancy data could identify men with favorable post-radiation prostate-specific antigen (PSA failure kinetics unlikely to require androgen deprivation therapy (ADT. Materials and Methods. Of 206 men with unfavorable-risk prostate cancer in a randomized trial of radiation versus radiation and ADT, 53 experienced a PSA failure and were followed without salvage ADT. Comorbidity, age and established prognostic factors were assessed for relationship to death using Cox regression analyses. Results. The median age at failure, interval to PSA failure, and PSA doubling time were 76.6 years (interquartile range [IQR]: 71.8–79.3, 49.1 months (IQR: 37.7–87.4, and 25 months (IQR: 13.1–42.8, respectively. After a median follow up of 4.0 years following PSA failure, 45% of men had died, none from prostate cancer and no one had developed metastases. Both increasing age at PSA failure (HR: 1.14; 95% CI: 1.03–1.25; P=0.008 and the presence of moderate to severe comorbidity (HR: 12.5; 95% CI: 3.81–41.0; P2 years following post-radiation PSA failure appear to be good candidates for observation without ADT intervention.

  16. Favorable Impact of Growth Hormone Treatment on Cholesterol Levels in Turner Syndrome

    Science.gov (United States)

    Kohno, Hitoshi; Igarashi, Yutaka; Ozono, Keiichi; Ohyama, Kenji; Ogawa, Masamichi; Osada, Hisao; Onigata, Kazumichi; Kanzaki, Susumu; Seino, Yoshiki; Takahashi, Hiroaki; Tajima, Toshihiro; Tachibana, Katsuhiko; Tanaka, Hiroyuki; Nishi, Yoshikazu; Hasegawa, Tomonobu; Fujieda, Kenji; Fujita, Keinosuke; Horikawa, Reiko; Yokoya, Susumu; Yorifuji, Toru; Tanaka, Toshiaki

    2012-01-01

    Background: Patients with Turner syndrome (TS) are prone to having metabolic abnormalities, such as obesity, dyslipidemia, hypertension, hyperinsulinemia and type 2 diabetes mellitus, resulting in increased risks of developing atherosclerotic diseases. Objective: To determine the effect of growth hormone (GH) therapy on serum cholesterol levels in prepubertal girls with TS enrolled in the Turner syndrome Research Collaboration (TRC) in Japan. Patients and methods: Eighty-one girls with TS were enrolled in the TRC, and their total cholesterol (TC) levels before GH therapy were compared with reported levels of healthy school-aged Japanese girls. TC levels after 1, 2 and 3 yr of GH treatment were available for 28 of the 81 patients with TS. GH was administered by daily subcutaneous injections, 6 or 7 times/wk, with a weekly dose of 0.35 mg/kg body weight. Results: Baseline TC levels revealed an age-related increase in TS that was in contrast to healthy girls showing unchanged levels. During GH therapy, TC decreased significantly after 1 yr of GH treatment and remained low thereafter. Conclusions: Girls with untreated TS showed an age-related increase in TC that was a striking contrast to healthy girls, who showed unchanged levels. GH therapy in girls with TS brought about a favorable change in TC that indicates the beneficial impact of GH on atherogenic risk. PMID:23926408

  17. Aerosol deposition favors red tide phytoplankton in the East China Sea

    Science.gov (United States)

    Mackey, K. R.; Chien, C.; Chen, Y.; Glover, D. M.; Paytan, A.

    2013-12-01

    Chinese marginal seas support vast fisheries and vital economies, but their productivity is threatened by eutrophication from runoff and atmospheric deposition. The East China Sea is inundated with nitrogen from the Yangtze River and anthropogenic emissions, leading to elevated N:P ratios. We show that aerosol additions approximating one week of moderate deposition to offshore waters favor the growth of red tide phytoplankton, such as Skeletonema costatum, by providing nutrients and trace metals (iron and zinc) needed for growth. In contrast toxin-producing Pseudonitzchia does not benefit from aerosols in this region, possibly due to its preference for lower N:P ratios. A dose-dependent toxic response was observed in Synechococcus at high aerosol loads approximating a week of heavy deposition in the region. In contrast, phytoplankton growth at an onshore station was light limited, and aerosol additions did not have an appreciable effect on phytoplankton growth. Aerosol and chlorophyll observations from the Moderate Resolution Imaging Spectroradiometer (MODIS) satellite have the potential to explore the effect of aerosols on phytoplankton blooms over longer time scales and seasons. This study shows the potential for aerosols to control N:P ratios in offshore waters and to shape the phytoplankton community through fertilization and toxicity, contributing to the occurrence of red tides.

  18. TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration.

    Directory of Open Access Journals (Sweden)

    Adrien Rousseau

    2013-12-01

    Full Text Available Tumor necrosis factor (TNF receptor-associated factor 4 (TRAF4 is frequently overexpressed in carcinomas, suggesting a specific role in cancer. Although TRAF4 protein is predominantly found at tight junctions (TJs in normal mammary epithelial cells (MECs, it accumulates in the cytoplasm of malignant MECs. How TRAF4 is recruited and functions at TJs is unclear. Here we show that TRAF4 possesses a novel phosphoinositide (PIP-binding domain crucial for its recruitment to TJs. Of interest, this property is shared by the other members of the TRAF protein family. Indeed, the TRAF domain of all TRAF proteins (TRAF1 to TRAF6 is a bona fide PIP-binding domain. Molecular and structural analyses revealed that the TRAF domain of TRAF4 exists as a trimer that binds up to three lipids using basic residues exposed at its surface. Cellular studies indicated that TRAF4 acts as a negative regulator of TJ and increases cell migration. These functions are dependent from its ability to interact with PIPs. Our results suggest that TRAF4 overexpression might contribute to breast cancer progression by destabilizing TJs and favoring cell migration.

  19. Exploring the favorable ion-exchange ability of phthalylated cellulose biopolymer using thermodynamic data.

    Science.gov (United States)

    de Melo, Júlio C P; da Silva Filho, Edson C; Santana, Sirlane A A; Airoldi, Claudio

    2010-09-01

    A phthalylated ion-exchange biopolymer was obtained by adding cellulose to molten phthalic anhydride in a quasi solvent-free procedure. Through this route 2.99+/-0.07 mmolg(-1) of pendant groups containing ester and carboxylic acid moieties were incorporated into the polymeric structure that was characterized by elemental analysis, solid-state carbon nuclear magnetic resonance (CP/MAS), infrared spectroscopy, X-ray diffraction, and thermogravimetry. The chemically modified polysaccharide is able to exchange cations from aqueous solution as demonstrated by batchwise methodology. The data were adjusted to a modified Langmuir equation to give 2.43+/-0.12 and 2.26+/-0.11 mmolg(-1) for divalent cobalt and nickel cations, respectively. The net thermal effects obtained from calorimetric titration measurements were also adjusted to a modified Langmuir equation, and the enthalpy of the interaction was calculated to give endothermic values of 2.11+/-0.28 and 2.50+/-0.31kJmol(-1) for these cations, respectively. The spontaneity of this ion-exchange process is reflected in negative Gibbs energy and with a contribution of positive entropic values. This set of thermodynamic data at the solid-liquid interface suggests a favorable ion-exchange process for this anchored biopolymer for cation exchange from the environment. PMID:20673881

  20. Do Code of Points in men artistic gymnastics and women artistic gymnastics favor asymmetric elements?

    Directory of Open Access Journals (Sweden)

    Ivan ČUK

    2016-03-01

    Full Text Available Abstract The purpose of research was to determine whether Code of Point (COP in Men Artistic Gymnastics (MAG and Women Artistic Gymnastics (WAG favor asymmetric elements in order to build gymnast’s competition exercise. All elements which are described in MAG (N = 993 and WAG (N = 713 COP were included and defined if they are symmetric at start position, during movement and at final position. Element is symmetric by arms and trunk with legs activity when all left and right body side performs simultaneously same activity. Results show in MAG COP as a whole is significantly more asymmetric elements with asymmetric trunk and legs activity. In WAG COP as a whole is significantly more asymmetric elements with asymmetric activity of arms, trunk and legs. Hypothetical most difficulty exercises on each apparatus revealed that in general for all around gymnast proportion between asymmetric and symmetric elements is close to 70% to 30%, what suggests that difficulty relates to increased asymmetry. COP in MAG and WAG enforces asymmetric movements for achieving high results, however, coaches’ task is to be aware of COP influence on gymnasts’ health and minimize asymmetries in load and to work on symmetric conditioning.

  1. An electron-accepting molecular unit exhibiting an orientational preference favorable for organic photovoltaic applications

    International Nuclear Information System (INIS)

    Control of molecular orientation of organic semiconductor is essential for efficient light absorption and charge-carrier transport in organic optoelectronic devices. We synthesized compound 1 as a fundamental electron-accepting building block for the design of n-type semiconductors and conducting polymers. We found that this molecule, upon evaporation onto a substrate such as SiO2 and electron-donor films, spontaneously assembles with a face-on orientation relative to the substrate surface. This orientation is favorable for thin-film organic photovoltaics. Despite relatively small π-conjugation, 1 showed strong absorption in visible-light region and an appropriate lowest unoccupied molecular orbital energy for electron transfer with electron donors including copper phthalocyanine and poly(3-hexylthiophene). Accordingly, thin-film devices, fabricated using 1 and electron donors, exhibited a clear photovoltaic response. This suggests that compound 1 provides a promising building block for the development of active materials in organic photovoltaics. - Highlights: • An electron acceptor (1) featuring an indacenetetraone core was designed. • Acceptor 1 exhibits strong electronic absorption in visible-light region. • Acceptor 1 spontaneously adopts face-on orientation on SiO2 and organic substrates. • Thin film of 1 shows an n-type semiconducting property. • Electron donor/1 bilayer films display a clear photovoltaic response

  2. Social heuristics and social roles: Intuition favors altruism for women but not for men.

    Science.gov (United States)

    Rand, David G; Brescoll, Victoria L; Everett, Jim A C; Capraro, Valerio; Barcelo, Hélène

    2016-04-01

    Are humans intuitively altruistic, or does altruism require self-control? A theory of social heuristics, whereby intuitive responses favor typically successful behaviors, suggests that the answer may depend on who you are. In particular, evidence suggests that women are expected to behave altruistically, and are punished for failing to be altruistic, to a much greater extent than men. Thus, women (but not men) may internalize altruism as their intuitive response. Indeed, a meta-analysis of 13 new experiments and 9 experiments from other groups found that promoting intuition relative to deliberation increased giving in a Dictator Game among women, but not among men (Study 1, N = 4,366). Furthermore, this effect was shown to be moderated by explicit sex role identification (Study 2, N = 1,831): the more women described themselves using traditionally masculine attributes (e.g., dominance, independence) relative to traditionally feminine attributes (e.g., warmth, tenderness), the more deliberation reduced their altruism. Our findings shed light on the connection between gender and altruism, and highlight the importance of social heuristics in human prosociality. PMID:26913619

  3. Anthropogenic N deposition slows decay by favoring bacterial metabolism: Insights from metagenomic analyses

    Directory of Open Access Journals (Sweden)

    Zachary B. Freedman

    2016-03-01

    Full Text Available Litter decomposition is an enzymatically-complex process that is mediated by a diverse assemblage of saprophytic microorganisms. It is a globally important biogeochemical process that can be suppressed by anthropogenic N deposition. In a northern hardwood forest ecosystem located in Michigan, USA, 20 years of experimentally increased atmospheric N deposition has reduced forest floor decay and increased soil C storage. Here, we paired extracellular enzyme assays with shotgun metagenomics to assess if anthropogenic N deposition has altered the functional potential of microbial communities inhabiting decaying forest floor. Experimental N deposition significantly reduced the activity of extracellular enzymes mediating plant cell wall decay, which occurred concurrently with changes in the relative abundance of metagenomic functional gene pathways mediating the metabolism of carbohydrates, aromatic compounds, as well as microbial respiration. Moreover, experimental N deposition increased the relative abundance of 50 of the 60 gene pathways, the majority of which were associated with saprotrophic bacteria. Conversely, the relative abundance and composition of fungal genes mediating the metabolism of plant litter was not affected by experimental N deposition. Future rates of atmospheric N deposition have favored saprotrophic soil bacteria, whereas the metabolic potential of saprotrophic fungi appears resilient to this agent of environmental change. Results presented here provide evidence that changes in the functional capacity of saprotrophic soil microorganisms mediate how anthropogenic N deposition increases C storage in soil.

  4. Soluble OX40L favors tumor rejection in CT26 colon carcinoma model.

    Science.gov (United States)

    Serebrovskaya, Ekaterina O; Yuzhakova, Diana V; Ryumina, Alina P; Druzhkova, Irina N; Sharonov, George V; Kotlobay, Alexey A; Zagaynova, Elena V; Lukyanov, Sergey A; Shirmanova, Marina V

    2016-08-01

    OX40 receptor-expressing regulatory T cells (Tregs) populate tumors and suppress a variety of immune cells, posing a major obstacle for cancer immunotherapy. Different ways to functionally inactivate Tregs by triggering OX40 receptor have been suggested, including anti-OX40 antibodies and Fc:OX40L fusion proteins. To investigate whether the soluble extracellular domain of OX40L (OX40Lexo) is sufficient to enhance antitumor immune response, we generated an OX40Lexo-expressing CT26 colon carcinoma cell line and studied its tumorigenicity in immunocompetent BALB/c and T cell deficient nu/nu mice. We found that soluble OX40L expressed in CT26 colon carcinoma favors the induction of an antitumor response which is not limited just to cells co-expressing EGFP as an antigenic determinant, but also eliminates CT26 cells expressing another fluorescent protein, KillerRed. Tumor rejection required the presence of T lymphocytes, as indicated by the unhampered tumor growth in nu/nu mice. Subsequent re-challenge of tumor-free BALB/c mice with CT26 EGFP cells resulted in no tumor growth, which is indicative of the formation of immunological memory. Adoptive transfer of splenocytes from mice that successfully rejected CT26 OX40Lexo EGFP tumors to naïve mice conferred 100% resistance to subsequent challenge with the CT26 EGFP tumor. PMID:27203665

  5. An electron-accepting molecular unit exhibiting an orientational preference favorable for organic photovoltaic applications

    Energy Technology Data Exchange (ETDEWEB)

    Akaike, Kouki, E-mail: kakaike@physik.hu-berlin.de [RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Ando, Shinji; Enozawa, Hideo [RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Kosaka, Atsuko; Kajitani, Takashi [RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Kanagawa 226-8503 (Japan); Fukushima, Takanori, E-mail: fukushima@res.titech.ac.jp [RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Kanagawa 226-8503 (Japan)

    2015-05-29

    Control of molecular orientation of organic semiconductor is essential for efficient light absorption and charge-carrier transport in organic optoelectronic devices. We synthesized compound 1 as a fundamental electron-accepting building block for the design of n-type semiconductors and conducting polymers. We found that this molecule, upon evaporation onto a substrate such as SiO{sub 2} and electron-donor films, spontaneously assembles with a face-on orientation relative to the substrate surface. This orientation is favorable for thin-film organic photovoltaics. Despite relatively small π-conjugation, 1 showed strong absorption in visible-light region and an appropriate lowest unoccupied molecular orbital energy for electron transfer with electron donors including copper phthalocyanine and poly(3-hexylthiophene). Accordingly, thin-film devices, fabricated using 1 and electron donors, exhibited a clear photovoltaic response. This suggests that compound 1 provides a promising building block for the development of active materials in organic photovoltaics. - Highlights: • An electron acceptor (1) featuring an indacenetetraone core was designed. • Acceptor 1 exhibits strong electronic absorption in visible-light region. • Acceptor 1 spontaneously adopts face-on orientation on SiO{sub 2} and organic substrates. • Thin film of 1 shows an n-type semiconducting property. • Electron donor/1 bilayer films display a clear photovoltaic response.

  6. The ecological conditions that favor tool use and innovation in wild bottlenose dolphins (Tursiops sp.).

    Science.gov (United States)

    Patterson, Eric M; Mann, Janet

    2011-01-01

    Dolphins are well known for their exquisite echolocation abilities, which enable them to detect and discriminate prey species and even locate buried prey. While these skills are widely used during foraging, some dolphins use tools to locate and extract prey. In the only known case of tool use in free-ranging cetaceans, a subset of bottlenose dolphins (Tursiops sp.) in Shark Bay, Western Australia habitually employs marine basket sponge tools to locate and ferret prey from the seafloor. While it is clear that sponges protect dolphins' rostra while searching for prey, it is still not known why dolphins probe the substrate at all instead of merely echolocating for buried prey as documented at other sites. By 'sponge foraging' ourselves, we show that these dolphins target prey that both lack swimbladders and burrow in a rubble-littered substrate. Delphinid echolocation and vision are critical for hunting but less effective on such prey. Consequently, if dolphins are to access this burrowing, swimbladderless prey, they must probe the seafloor and in turn benefit from using protective sponges. We suggest that these tools have allowed sponge foraging dolphins to exploit an empty niche inaccessible to their non-tool-using counterparts. Our study identifies the underlying ecological basis of dolphin tool use and strengthens our understanding of the conditions that favor tool use and innovation in the wild. PMID:21799801

  7. The ecological conditions that favor tool use and innovation in wild bottlenose dolphins (Tursiops sp..

    Directory of Open Access Journals (Sweden)

    Eric M Patterson

    Full Text Available Dolphins are well known for their exquisite echolocation abilities, which enable them to detect and discriminate prey species and even locate buried prey. While these skills are widely used during foraging, some dolphins use tools to locate and extract prey. In the only known case of tool use in free-ranging cetaceans, a subset of bottlenose dolphins (Tursiops sp. in Shark Bay, Western Australia habitually employs marine basket sponge tools to locate and ferret prey from the seafloor. While it is clear that sponges protect dolphins' rostra while searching for prey, it is still not known why dolphins probe the substrate at all instead of merely echolocating for buried prey as documented at other sites. By 'sponge foraging' ourselves, we show that these dolphins target prey that both lack swimbladders and burrow in a rubble-littered substrate. Delphinid echolocation and vision are critical for hunting but less effective on such prey. Consequently, if dolphins are to access this burrowing, swimbladderless prey, they must probe the seafloor and in turn benefit from using protective sponges. We suggest that these tools have allowed sponge foraging dolphins to exploit an empty niche inaccessible to their non-tool-using counterparts. Our study identifies the underlying ecological basis of dolphin tool use and strengthens our understanding of the conditions that favor tool use and innovation in the wild.

  8. Type II ligands as chemical auxiliaries to favor enzymatic transformations by P450 2E1.

    Science.gov (United States)

    Ménard, Amélie; Fabra, Camilo; Huang, Yue; Auclair, Karine

    2012-11-26

    The remarkable ability of P450 enzymes to oxidize inactivated C-H bonds and the high substrate promiscuity of many P450 isoforms have inspired us and others to investigate their use as biocatalysts. Our lab has pioneered a chemical-auxiliary approach to control the promiscuity of P450 3A4 and provide product predictability. The recent realization that type II ligands are sometimes also P450 substrates has prompted the design of a new generation of chemical auxiliaries with type II binding properties. This approach takes advantage of the high affinity of type II ligands for the active site of these enzymes. Although type II ligands typically block P450 activity, we report here that type II ligation can be harnessed to achieve just the opposite, that is, to favor biocatalysis and afford predictable oxidation of small hydrocarbon substrates with P450 2E1. Moreover, the observed predictability was rationalized by molecular docking. We hope that this approach might find future use with other P450 isoforms and yield complimentary products. PMID:23129539

  9. Music, clicks, and their imaginations favor differently the event-based timing component for rhythmic movements.

    Science.gov (United States)

    Bravi, Riccardo; Quarta, Eros; Del Tongo, Claudia; Carbonaro, Nicola; Tognetti, Alessandro; Minciacchi, Diego

    2015-06-01

    The involvement or noninvolvement of a clock-like neural process, an effector-independent representation of the time intervals to produce, is described as the essential difference between event-based and emergent timing. In a previous work (Bravi et al. in Exp Brain Res 232:1663-1675, 2014a. doi: 10.1007/s00221-014-3845-9 ), we studied repetitive isochronous wrist's flexion-extensions (IWFEs), performed while minimizing visual and tactile information, to clarify whether non-temporal and temporal characteristics of paced auditory stimuli affect the precision and accuracy of the rhythmic motor performance. Here, with the inclusion of new recordings, we expand the examination of the dataset described in our previous study to investigate whether simple and complex paced auditory stimuli (clicks and music) and their imaginations influence in a different way the timing mechanisms for repetitive IWFEs. Sets of IWFEs were analyzed by the windowed (lag one) autocorrelation-wγ(1), a statistical method recently introduced for the distinction between event-based and emergent timing. Our findings provide evidence that paced auditory information and its imagination favor the engagement of a clock-like neural process, and specifically that music, unlike clicks, lacks the power to elicit event-based timing, not counteracting the natural shift of wγ(1) toward positive values as frequency of movements increase. PMID:25837726

  10. Anticipated detection of favorable periods for wind energy production by means of information theory

    Science.gov (United States)

    Vogel, Eugenio; Saravia, Gonzalo; Kobe, Sigismund; Schumann, Rolf; Schuster, Rolf

    Managing the electric power produced by different sources requires mixing the different response times they present. Thus, for instance, coal burning presents large time lags until operational conditions are reached while hydroelectric generation can react in a matter of some seconds or few minutes to reach the desired productivity. Wind energy production (WEP) can be instantaneously fed to the network to save fuels with low thermal inertia (gas burning for instance), but this source presents sudden variations within few hours. We report here for the first time a method based on information theory to handle WEP. This method has been successful in detecting dynamical changes in magnetic transitions and variations of stock markets. An algorithm called wlzip based on information recognition is used to recognize the information content of a time series. We make use of publically available energy data in Germany to simulate real applications. After a calibration process the system can recognize directly on the WEP data the onset of favorable periods of a desired strength. Optimization can lead to a few hours of anticipation which is enough to control the mixture of WEP with other energy sources, thus saving fuels.

  11. Favorable climate change response explains non-native species' success in Thoreau's woods.

    Directory of Open Access Journals (Sweden)

    Charles G Willis

    Full Text Available Invasive species have tremendous detrimental ecological and economic impacts. Climate change may exacerbate species invasions across communities if non-native species are better able to respond to climate changes than native species. Recent evidence indicates that species that respond to climate change by adjusting their phenology (i.e., the timing of seasonal activities, such as flowering have historically increased in abundance. The extent to which non-native species success is similarly linked to a favorable climate change response, however, remains untested. We analyzed a dataset initiated by the conservationist Henry David Thoreau that documents the long-term phenological response of native and non-native plant species over the last 150 years from Concord, Massachusetts (USA. Our results demonstrate that non-native species, and invasive species in particular, have been far better able to respond to recent climate change by adjusting their flowering time. This demonstrates that climate change has likely played, and may continue to play, an important role in facilitating non-native species naturalization and invasion at the community level.

  12. Favorable climate change response explains non-native species' success in Thoreau's woods.

    Science.gov (United States)

    Willis, Charles G; Ruhfel, Brad R; Primack, Richard B; Miller-Rushing, Abraham J; Losos, Jonathan B; Davis, Charles C

    2010-01-01

    Invasive species have tremendous detrimental ecological and economic impacts. Climate change may exacerbate species invasions across communities if non-native species are better able to respond to climate changes than native species. Recent evidence indicates that species that respond to climate change by adjusting their phenology (i.e., the timing of seasonal activities, such as flowering) have historically increased in abundance. The extent to which non-native species success is similarly linked to a favorable climate change response, however, remains untested. We analyzed a dataset initiated by the conservationist Henry David Thoreau that documents the long-term phenological response of native and non-native plant species over the last 150 years from Concord, Massachusetts (USA). Our results demonstrate that non-native species, and invasive species in particular, have been far better able to respond to recent climate change by adjusting their flowering time. This demonstrates that climate change has likely played, and may continue to play, an important role in facilitating non-native species naturalization and invasion at the community level. PMID:20126652

  13. Stereotactic ablative radiotherapy for small lung tumors with a moderate dose. Favorable results and low toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Duncker-Rohr, V.; Nestle, U. [Universitaetsklinikum Freiburg (Germany); Momm, F. [Ortenau Klinikum Offenburg (Germany)] [and others

    2013-01-15

    Background: Stereotactic ablative body radiotherapy (SBRT, SABR) is being increasingly applied because of its high local efficacy, e.g., for small lung tumors. However, the optimum dosage is still under discussion. Here, we report data on 45 lung lesions [non-small cell lung cancer (NSCLC) or metastases] in 39 patients treated between 2009 and 2010 by SABR. Patients and methods: SABR was performed with total doses of 35 Gy (5 fractions) or 37.5 Gy (3 fractions) prescribed to the 60% isodose line encompassing the planning target volume. Three-monthly follow-up CT scans were supplemented by FDG-PET/CT if clinically indicated. Results: The median follow-up was 17 months. Local progression-free survival rates were 90.5% (all patients), 95.0% (NSCLC), and 81.8% (metastases) at 1 year. At 2 years, the respective local progression-free survival rates were 80.5%, 95.0%, and 59.7%. Overall survival rates were 71.1% (all patients), 65.4% (NSCLC), and 83.3% (metastases) at 1 year. Overall survival rates at 2 years were 52.7%, 45.9%, and 66.7%, respectively. Acute side effects were mild. Conclusion: With the moderate dose schedule used, well-tolerated SABR led to favorable local tumor control as in other published series. Standardization in reporting the dose prescription for SABR is needed to allow comparison of different series in order to determine optimum dosage. (orig.)

  14. Geología de la quebrada Honda, cuenca del lago La Plata, Chubut Geology of the Quebrada Honda, basin of Lago La Plata, Chubut

    Directory of Open Access Journals (Sweden)

    G.V. Depine

    2004-12-01

    Full Text Available La quebrada Honda, situada en el sur de la cuenca de los lagos La Plata y Fontana, en la provincia de Chubut, presenta una columna estratigráfica que comienza en el Jurásico superior con rocas calcoalcalinas de arco volcánico intermedias a ácidas de la Formación Lago La Plata. Las rocas sedimentarias que rellenan la cuenca de intraarco neocomiana corresponden al Grupo Coyhaique, dentro del cual se encuentran las Formaciones Tres Lagunas y Katterfeld, que se ubican dentro de un modelo paleoambiental como cortejo sedimentario de borde de plataforma, sucedido por un cortejo transgresivo, cuya edad es acotada al Hauteriviano inferior, debido al hallazgo de restos de Favrella americana en pelitas de la Formación Katterfeld. Vinculados con la extensión que da lugar a la cuenca se registran los cuerpos hipabisales calcoalcalinos básicos del Gabro Quebrada Honda y se los relaciona con un volcanismo de características más evolucionadas de la Formación Don Rueda, de edad neocomiana tardía. Si bien este magmatismo de arco volcánico es subaéreo, presenta indicios de interacción con cuerpos de agua por lo que corrobora la concomitancia de este evento con la sedimentación póstuma de Grupo Coyhaique. Se registra un evento de inversión tectónica que tendría una edad máxima de 80 Ma.The quebrada Honda is situated in the Lago La Plata-Fontana basin in Chubut. The stratigraphy of the area begins in the Upper Jurassic with the calc-alkaline intermediate to acidic Lago La Plata Formation rocks. The Neocomian Coyhaique Group, which includes the Tres Lagunas and Katterfeld Formations, is the sedimentary filling of the intraarc basin that was developed by that time. These units are included in a paleoenviromental model as a shelf-margin system tract followed by a transgressive system tract. The discovery of Favrella americana in the Katterfeld Formation constrains to the Early Hauterivian the age of these sequences. The hypabissal calc

  15. K-Basins design guidelines

    Energy Technology Data Exchange (ETDEWEB)

    Roe, N.R.; Mills, W.C.

    1995-06-01

    The purpose of the design guidelines is to enable SNF and K Basin personnel to complete fuel and sludge removal, and basin water mitigation by providing engineering guidance for equipment design for the fuel basin, facility modifications (upgrades), remote tools, and new processes. It is not intended to be a purchase order reference for vendors. The document identifies materials, methods, and components that work at K Basins; it also Provides design input and a technical review process to facilitate project interfaces with operations in K Basins. This document is intended to compliment other engineering documentation used at K Basins and throughout the Spent Nuclear Fuel Project. Significant provisions, which are incorporated, include portions of the following: General Design Criteria (DOE 1989), Standard Engineering Practices (WHC-CM-6-1), Engineering Practices Guidelines (WHC 1994b), Hanford Plant Standards (DOE-RL 1989), Safety Analysis Manual (WHC-CM-4-46), and Radiological Design Guide (WHC 1994f). Documents (requirements) essential to the engineering design projects at K Basins are referenced in the guidelines.

  16. K-Basins design guidelines

    International Nuclear Information System (INIS)

    The purpose of the design guidelines is to enable SNF and K Basin personnel to complete fuel and sludge removal, and basin water mitigation by providing engineering guidance for equipment design for the fuel basin, facility modifications (upgrades), remote tools, and new processes. It is not intended to be a purchase order reference for vendors. The document identifies materials, methods, and components that work at K Basins; it also Provides design input and a technical review process to facilitate project interfaces with operations in K Basins. This document is intended to compliment other engineering documentation used at K Basins and throughout the Spent Nuclear Fuel Project. Significant provisions, which are incorporated, include portions of the following: General Design Criteria (DOE 1989), Standard Engineering Practices (WHC-CM-6-1), Engineering Practices Guidelines (WHC 1994b), Hanford Plant Standards (DOE-RL 1989), Safety Analysis Manual (WHC-CM-4-46), and Radiological Design Guide (WHC 1994f). Documents (requirements) essential to the engineering design projects at K Basins are referenced in the guidelines

  17. On the contribution of groundwater storage to interannual streamflow anomalies in the Colorado River basin

    Directory of Open Access Journals (Sweden)

    E. A. Rosenberg

    2013-04-01

    Full Text Available We assess the significance of groundwater storage for seasonal streamflow forecasts by evaluating its contribution to interannual streamflow anomalies in the 29 tributary sub-basins of the Colorado River. Monthly and annual changes in total basin storage are simulated by two implementations of the Variable Infiltration Capacity (VIC macroscale hydrology model – the standard release of the model, and an alternate version that has been modified to include the SIMple Groundwater Model (SIMGM, which represents an unconfined aquifer underlying the soil column. These estimates are compared to those resulting from basin-scale water balances derived exclusively from observational data and changes in terrestrial water storage from the Gravity Recovery and Climate Experiment (GRACE satellites. Changes in simulated groundwater storage are then compared to those derived via baseflow recession analysis for 72 reference-quality watersheds. Finally, estimates are statistically analyzed for relationships to interannual streamflow anomalies, and predictive capacities are compared across storage terms. We find that both model simulations result in similar estimates of total basin storage change, that these estimates compare favorably with those obtained from basin-scale water balances and GRACE data, and that baseflow recession analyses are consistent with simulated changes in groundwater storage. Statistical analyses reveal essentially no relationship between groundwater storage and interannual streamflow anomalies, suggesting that operational seasonal streamflow forecasts, which do not account for groundwater conditions implicitly or explicitly, are likely not detrimentally affected by this omission in the Colorado River basin.

  18. Implications of Texture and Erodibility for Sediment Retention in Receiving Basins of Coastal Louisiana Diversions

    Directory of Open Access Journals (Sweden)

    Kehui Xu

    2016-01-01

    Full Text Available Although the Mississippi River deltaic plain has been the subject of abundant research over recent decades, there is a paucity of data concerning field measurement of sediment erodibility in Louisiana estuaries. Two contrasting receiving basins for active diversions were studied: West Bay on the western part of Mississippi River Delta and Big Mar, which is the receiving basin for the Caernarvon freshwater diversion. Push cores and water samples were collected at six stations in West Bay and six stations in Big Mar. The average erodibility of Big Mar sediment was similar to that of Louisiana shelf sediment, but was higher than that of West Bay. Critical shear stress to suspend sediment in both West Bay and Big Mar receiving basins was around 0.2 Pa. A synthesis of 1191 laser grain size data from surficial and down-core sediment reveals that silt (4–63 μm is the largest fraction of retained sediment in receiving basins, larger than the total of sand (>63 μm and clay (<4 μm. It is suggested that preferential delivery of fine grained sediment to more landward and protected receiving basins would enhance mud retention. In addition, small fetch sizes and fragmentation of large receiving basins are favorable for sediment retention.

  19. Division of coalbed methane-enriched units in the Qinshui Basin

    Institute of Scientific and Technical Information of China (English)

    ZHAO Jingzhou; SHI Baohong

    2005-01-01

    Division of CBM (coalbed methane)-enriched units is an important precondition and basic work for formulation of scientific CBM exploration procedure and improvement of CBM exploration success rate. In consideration of the CBM particularity and complexity as well as its distribution in China, the CBM-enriched units are divided into 5 levels, i.e. CBM-bearing region, CBM-bearing basin, CBMenriched area, CBM-enriched zone, and CBM reservoir (field). The Qinshui Basin is one of the China's richest CBM basins with higher exploration degree. However, division and study of CBM-enriched units are relatively weak for the basin. Based on geological conditions of CBM reservoirs formarion and current distribution of CBM reservoirs in the Qinshui Basin, this paper divides the basin into 5 CBM-enriched areas, that is, the South Qinshui, Eastern Slope,Western Slope, Xishan, and Gaoping-Jincheng CBM-enriched areas. Of those 5 areas, the South Qinshui is most favorable for CBM exploration.

  20. On the contribution of groundwater storage to interannual streamflow anomalies in the Colorado River basin

    Directory of Open Access Journals (Sweden)

    E. A. Rosenberg

    2012-11-01

    Full Text Available We assess the significance of groundwater storage for seasonal streamflow forecasts by evaluating its contribution to interannual streamflow anomalies in the 29 tributary sub-basins of the Colorado River. Monthly and annual changes in total basin storage are simulated by two implementations of the Variable Infiltration Capacity (VIC macroscale hydrology model – the standard release of the model, and an alternate version that has been modified to include the SIMple Groundwater Model (SIMGM, which represents an unconfined aquifer underlying the soil column. These estimates are compared to those resulting from basin-scale water balances derived exclusively from observational data and changes in terrestrial water storage from the Gravity Recovery and Climate Experiment (GRACE satellites. Changes in simulated groundwater storage are then compared to those derived via baseflow recession analysis for 72 reference-quality watersheds. Finally, estimates are statistically analyzed for relationships to interannual streamflow anomalies, and predictive capacities are compared across storage terms. We find that both model simulations result in similar estimates of total basin storage change, that these estimates compare favorably with those obtained from basin-scale water balances and GRACE data, and that baseflow recession analyses are consistent with simulated changes in groundwater storage. Statistical analyses reveal essentially no relationship between groundwater storage and interannual streamflow anomalies, suggesting that operational seasonal streamflow forecasts, which do not account for groundwater conditions implicitly or explicitly, are likely not detrimentally affected by this omission in the Colorado River basin.

  1. Marketing San Juan Basin gas

    International Nuclear Information System (INIS)

    Marketing natural gas produced in the San Juan Basin of New Mexico and Colorado principally involves four gas pipeline companies with significant facilities in the basin. The system capacity, transportation rates, regulatory status, and market access of each of these companies is evaluated. Because of excess gas supplies available to these pipeline companies, producers can expect improved take levels and prices by selling gas directly to end users and utilities as opposed to selling gas to the pipelines for system supply. The complexities of transporting gas today suggest that the services of an independent gas marketing company may be beneficial to smaller producers with gas supplies in the San Juan Basin

  2. Western Canada Sedimentary Basin competitiveness

    International Nuclear Information System (INIS)

    Recent dramatic expansion of the natural gas industry in the Western Canada Sedimentary Basin provided ample proof of the potential of this area for further development of natural gas supply. However, the inherent competitive advantages provided by the Western Canada Sedimentary Basin were said to have been offset by low netback prices resulting in poor producer economics when competitiveness is measured by availability of opportunities to find and develop gas supply at costs low enough to ensure attractive returns. Technology was identified as one of the key elements in improving basin competitiveness, but the greatest potential lies in reduced transportation costs and increased access to North American market centres. 8 figs

  3. Does the combination of radiotherapy and debulking surgery favor survival in paranasal sinus carcinoma?

    International Nuclear Information System (INIS)

    an unfavorable outcome. In 19 of 73 patients, 26 serious (mainly ophthalmological) complications were reported; in the majority of these, the visual tract was (partly) included in the treatment fields because of tumor extension. To analyze on which basis patients were selected for the combination therapy, a logistic regression was performed, concluding that clinical T4 classification (p = 0.05), radiological evidence of skull base invasion (p = 0.005), age of greater than 65 years (p = 0.026), radiological evidence of nasopharynx invasion (p = 0.02), clinical suspicion of palate invasion (p = 0.02), and radiological evidence of skin invasion (p = 0.009) were associated with choosing radiotherapy alone. Conclusion: Debulking surgery of paranasal sinus malignancies followed by high-dose radiotherapy to the involved sites was associated with better survival and (although not statistically significant) local control. Patient selection, based on clinical and radiological impression of tumor extension, was the main factor explaining these favorable results. We favor this combination regimen because the surgery gives quick relief of complaints and, at the same time, offers an excellent histologically proven staging method, enabling radiotherapy to be adjusted to the involved sites, thereby decreasing the risk of complications. This can all be achieved with a very low orbital exenteration rate

  4. Inversion structure and its contribution to sandstone uranium metallogenesis in southeast uplifted domain of Songliao basin

    International Nuclear Information System (INIS)

    Many positive inversion structures were developed during the end of Nenjiang period in southeast Songliao basin Main styles of inversion structures are inversion anticline in downfaulted and depression sequence, positive footwall and negative upthrown block in downfaulted sequence, negative footwall and upthrown block in downfaulted sequence, negative footwall and upthrown block in depression sequence. Structure inversions may contribute to sandstone uranium ore-formation because they changed the structure shape, physical properties, circulating way of groundwater, geochemical property of rocks in shallow depression layer of the basin and lead to the ascending migration of oil-gas, CO2. Thus, denudation window areas are favorable for sandstone uranium ore-formation and attention must be paid to denudation window areas in Southeast uplifted domain of Songliao basin. (authors)

  5. Design of a novel chimeric tissue plasminogen activator with favorable Vampire bat plasminogen activator properties.

    Science.gov (United States)

    Kazemali, MohammadReza; Majidzadeh-A, Keivan; Sardari, Soroush; Saadatirad, Amir Hossein; Khalaj, Vahid; Zarei, Najmeh; Barkhordari, Farzaneh; Adeli, Ahmad; Mahboudi, Fereidoun

    2014-12-01

    Fibrinolytic agents are widely used in treatment of the thromboembolic disorders. The new generations like recombinant tissue plasminogen activator (t-PA, alteplase) are not showing promising results in clinical practice in spite of displaying specific binding to fibrin in vitro. Vampire bat plasminogen activator (b-PA) is a plasminogen activator with higher fibrin affinity and specificity in comparison to t-PA resulting in reduced probability of hemorrhage. b-PA is also resistant to plasminogen activator inhibitor-1 (PAI-1) showing higher half-life compared to other variants of t-PA. However, its non-human origin was a driving force to design a human t-PA with favorable properties of b-PA. In the present study, we designed a chimeric t-PA with desirable b-PA properties and this new molecule was called as CT-b. The construct was prepared through kringle 2 domain removal and replacement of t-PA finger domain with b-PA one. In addition, the KHRR sequence at the initial part of protease domain was replaced by four alanine residues. The novel construct was integrated in Pichia pastoris genome by electroporation. Catalytic activity was investigated in the presence and absence of fibrin. The purified protein was analyzed by western blot. Fibrin binding and PAI resistance assays were also conducted. The activity of the recombinant protein in the presence of fibrin was 1560 times more than its activity in the absence of fibrin, showing its higher specificity to fibrin. The fibrin binding of CT-b was 1.2 fold more than t-PA. In addition, it was inhibited by PAI enzyme 44% less than t-PA. Although the presented data demonstrate a promising in vitro activity, more in vivo studies are needed to confirm the therapeutic advantage of this novel plasminogen activator. PMID:25442953

  6. Chronic Voluntary Ethanol Consumption Induces Favorable Ceramide Profiles in Selectively Bred Alcohol-Preferring (P Rats.

    Directory of Open Access Journals (Sweden)

    Jessica Godfrey

    achieved by alcohol-preferring P rats as a result of chronic voluntary exposure may have favorable vs. detrimental effects on lipid profiles in this genetic line, consistent with data supporting beneficial cardioprotective and neuroprotective effects of moderate ethanol consumption.

  7. Aquatic pollution may favor the success of the invasive species A. franciscana

    International Nuclear Information System (INIS)

    Highlights: • Artemia species display an elevated tolerance to high ranges of chlorpyrifos. • A. franciscana survived better and its fecundity was less affected by chlorpyrifos. • The higher fecundity of A. franciscana is a selective advantage in colonization processes. • Higher survival and biological fitness in A. franciscana indicate out-competitive advantages. - Abstract: The genus Artemia consists of several bisexual and parthenogenetic sibling species. One of them, A. franciscana, originally restricted to the New World, becomes invasive when introduced into ecosystems out of its natural range of distribution. Invasiveness is anthropically favored by the use of cryptobiotic eggs in the aquaculture and pet trade. The mechanisms of out-competition of the autochthonous Artemia by the invader are still poorly understood. Ecological fitness may play a pivotal role, but other underlying biotic and abiotic factors may contribute. Since the presence of toxicants in hypersaline aquatic ecosystems has been documented, our aim here is to study the potential role of an organophosphate pesticide, chlorpyrifos, in a congeneric mechanism of competition between the bisexual A. franciscana (AF), and one of the Old World parthenogenetic siblings, A. parthenogenetica (PD). For this purpose we carried out life table experiments with both species, under different concentrations of the toxicant (0.1, 1 and 5 μg/l), and analyzed the cholinesterase inhibition at different developmental stages. The results evidence that both, AF and PD, showed an elevated tolerance to high ranges of chlorpyrifos, but AF survived better and its fecundity was less affected by the exposure to the pesticide than that of PD. The higher fecundity of AF is a selective advantage in colonization processes leading to its establishment as NIS. Besides, under the potential selective pressure of abiotic factors, such as the presence of toxicants, its higher resistance in terms of survival and biological

  8. Translocation t(11;14) in newly diagnosed patients with multiple myeloma: Is it always favorable?

    Science.gov (United States)

    Leiba, Merav; Duek, Adrian; Amariglio, Ninette; Avigdor, Abraham; Benyamini, Noam; Hardan, Izhar; Zilbershats, Itay; Ganzel, Chezi; Shevetz, Olga; Novikov, Ilya; Cohen, Yossi; Ishoev, Galina; Rozic, Gabriela; Nagler, Arnon; Trakhtenbrot, Luba

    2016-09-01

    The most common translocation in multiple myeloma (MM) is t(11;14)(q13;q32). According to several studies, this translocation represents a unique subset of patients with relatively favorable outcomes. Using combined analyses of morphology and fluorescence in situ hybridization (I-FISH), we examined the co-occurrence rates of t(11;14) with seven chromosomal aberrations (CAs), del(13q), del(17p), del(1p), gain(1q), multiple gains(1q), del(16q), and del(IGH), and assessed the effect of the different combinations on patient outcomes, with overall survival (OS) as the main outcome measure. Bone marrow samples and clinical data from 212 patients with MM with t(11;14) were analyzed. At least two additional CAs were found in 35% (75/205) of patients and a strong correlation between specific CAs. The occurrence of three CAs [multiple gains of (1q) (HR = 6.94, P = 0.001), del(1p) (HR = 4.47, P = 0.008), and del(IGH) (HR = 2.38, P = 0.002)] exerted a profoundly deleterious effect on median OS when compared with patients with t(11;14) only. Del(17p) and del(13q) have also exerted a deleterious effect albeit to a lesser extent (HR = 2.05, P = 0.07 and HR = 1.81, P = 0.03, respectively). When compared with t(11;14) alone, the addition of certain CAs lead to worse outcomes. These findings may have important clinical and biological implications. Patients with coexisting adverse lesions and t(11;14) may be considered at high risk and managed accordingly. © 2016 Wiley Periodicals, Inc. PMID:27152944

  9. Geology and uranium favorability of the Sonora Pass region, Alpine and Tuolumne Counties, California

    International Nuclear Information System (INIS)

    Uranium mineralization at the Juniper Mine is restricted to host rocks of the Relief Peak Formation and is most common in coarse-grained lithic sandstone, conglomerate, and lithic wacke. The richest beds contain as much as 0.5% U3O8. Uranium is present as coffinite, uraninite, and unidentified minerals. Thorium/uranium ratios are generally low and erratic. Equivalent uranium determinations are low in comparison with chemical uranium values, indicating that uranium mineralization of the Juniper Mine is geologically young. Core drilling at 16 localities shows that widely separated exposures of the Relief Peak Formation have very similar lithology, geochemistry, and stratigraphy. Some sections are similar to the Juniper Mine section. Core from the bottom of drill hole SP-1 contains 83 ppM uranium, the greatest known concentration outside the mine area. Significant uranium deposits may be concealed beneath the thick Tertiary volcanic cover of the region. The quartz latitic Eureka Valley Tuff is fairly widespread in east-central California and western Nevada. It contains 12 to 14 ppM uranium and stratigraphically overlies the Relief Peak Formation. It is permeable and contains abundant alkali metals and volcanic glass. Because of its petrology, geochemistry, and position, this formation is the most likely source for uranium mineralization of the Sonora Pass region. It should be examined as a potential source rock in other areas with special regard to its relationship to carbonaceous sedimentary formations. The uraniferous granite pegmatitite dike that crops out in the Niagara Creek area appears too small to be a significant source rock. The most favorable rocks in the Sonora Pass region occur near the Juniper Mine and west of it, in the Dardanelles, the Whittakers Dardanelles, and the area of the Big Meadow Quadrangle. Potential uranium host rocks crop out in areas along the crest of the Sierra Nevada from Lake Tahoe to Yosemite

  10. UVB radiation as a potential selective factor favoring microcystin producing bloom forming Cyanobacteria.

    Directory of Open Access Journals (Sweden)

    Yi Ding

    Full Text Available Due to the stratospheric ozone depletion, several organisms will become exposed to increased biologically active UVB (280-320 nm radiation, not only at polar but also at temperate and tropical latitudes. Bloom forming cyanobacteria are exposed to UVB radiation on a mass scale, particularly during the surface bloom and scum formation that can persist for long periods of time. All buoyant species of cyanobacteria are at least periodically exposed to higher irradiation during their vertical migration to the surface that usually occurs several times a day. The aim of this study is to assess the influence on cyanobacteria of UVB radiation at realistic environmental intensities. The effects of two UVB intensities of 0.5 and 0.99 W/m(2 in up to 0.5 cm water depth were studied in vitro on Microcystis aeruginosa strains, two microcystin producing and one non-producing. After UVB exposure their ability to proliferate was estimated by cell counting, while cell fitness and integrity were evaluated using light microscopy, autofluorescence and immunofluorescence. Gene damage was assessed by TUNEL assay and SYBR Green staining of the nucleoide area. We conclude that UVB exposure causes damage to the genetic material, cytoskeletal elements, higher sedimentation rates and consequent cell death. In contrast to microcystin producers (PCC7806 and FACHB905, the microcystin non-producing strain PCC7005 is more susceptible to the deleterious effects of radiation, with weak recovery ability. The ecological relevance of the results is discussed using data from eleven years' continuous UVB radiation measurements within the area of Ljubljana city (Slovenia, Central Europe. Our results suggest that increased solar radiation in temperate latitudes can have its strongest effect during cyanobacterial bloom formation in spring and early summer. UVB radiation in this period may significantly influence strain composition of cyanobacterial blooms in favor of microcystin producers.

  11. Aquatic pollution may favor the success of the invasive species A. franciscana

    Energy Technology Data Exchange (ETDEWEB)

    Varó, I., E-mail: inma@iats.csic.es [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain); Redón, S. [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain); Garcia-Roger, E.M. [Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Burjassot (Spain); Amat, F.; Guinot, D. [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain); Serrano, R. [Research Institute for Pesticides and Water (IUPA), Avda. Sos Baynat, s/n. University Jaume I, Castellón 12071 (Spain); Navarro, J.C. [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain)

    2015-04-15

    Highlights: • Artemia species display an elevated tolerance to high ranges of chlorpyrifos. • A. franciscana survived better and its fecundity was less affected by chlorpyrifos. • The higher fecundity of A. franciscana is a selective advantage in colonization processes. • Higher survival and biological fitness in A. franciscana indicate out-competitive advantages. - Abstract: The genus Artemia consists of several bisexual and parthenogenetic sibling species. One of them, A. franciscana, originally restricted to the New World, becomes invasive when introduced into ecosystems out of its natural range of distribution. Invasiveness is anthropically favored by the use of cryptobiotic eggs in the aquaculture and pet trade. The mechanisms of out-competition of the autochthonous Artemia by the invader are still poorly understood. Ecological fitness may play a pivotal role, but other underlying biotic and abiotic factors may contribute. Since the presence of toxicants in hypersaline aquatic ecosystems has been documented, our aim here is to study the potential role of an organophosphate pesticide, chlorpyrifos, in a congeneric mechanism of competition between the bisexual A. franciscana (AF), and one of the Old World parthenogenetic siblings, A. parthenogenetica (PD). For this purpose we carried out life table experiments with both species, under different concentrations of the toxicant (0.1, 1 and 5 μg/l), and analyzed the cholinesterase inhibition at different developmental stages. The results evidence that both, AF and PD, showed an elevated tolerance to high ranges of chlorpyrifos, but AF survived better and its fecundity was less affected by the exposure to the pesticide than that of PD. The higher fecundity of AF is a selective advantage in colonization processes leading to its establishment as NIS. Besides, under the potential selective pressure of abiotic factors, such as the presence of toxicants, its higher resistance in terms of survival and biological

  12. Consenting options for posthumous organ donation: presumed consent and incentives are not favored

    Directory of Open Access Journals (Sweden)

    Hammami Muhammad M

    2012-11-01

    Full Text Available Abstract Background Posthumous organ procurement is hindered by the consenting process. Several consenting systems have been proposed. There is limited information on public relative attitudes towards various consenting systems, especially in Middle Eastern/Islamic countries. Methods We surveyed 698 Saudi Adults attending outpatient clinics at a tertiary care hospital. Preference and perception of norm regarding consenting options for posthumous organ donation were explored. Participants ranked (1, most agreeable the following, randomly-presented, options from 1 to 11: no-organ-donation, presumed consent, informed consent by donor-only, informed consent by donor-or-surrogate, and mandatory choice; the last three options ± medical or financial incentive. Results Mean(SD age was 32(9 year, 27% were males, 50% were patients’ companions, 60% had ≥ college education, and 20% and 32%, respectively, knew an organ donor or recipient. Mandated choice was among the top three choices for preference of 54% of respondents, with an overall median[25%,75%] ranking score of 3[2,6], and was preferred over donor-or-surrogate informed consent (4[2,7], p vs. 11[6,11], respectively, p = 0.002. Compared to females, males more perceived donor-or-surrogate informed consent as the norm (3[1,6] vs. 5[3,7], p vs. 8[4,9], p vs. 5[2,7], p  Conclusions We conclude that: 1 most respondents were in favor of posthumous organ donation, 2 mandated choice system was the most preferred and presumed consent system was the least preferred, 3 there was no difference between preference and perception of norm in consenting systems ranking, and 4 financial (especially in females and medical (especially in males incentives reduced preference.

  13. Vaccination Against Human Papilloma Viruses Leads to a Favorable Cytokine Profile of Specific T Cells.

    Science.gov (United States)

    Luckau, Stefanie; Wehrs, Tim P; Brandau, Sven; Horn, Peter A; Lindemann, Monika

    2016-10-01

    Several human papilloma viruses (HPV) are known to cause malignant transformation. The high-risk type HPV 16 is associated with cervical carcinoma and head and neck squamous cell carcinoma. HPV 16-positive tumor cells exclusively carry the HPV 16 oncogenes E6 and E7. These oncogenes appear as excellent targets for an adoptive immunotherapy. We here addressed the question whether specific T cells from HPV-vaccinated healthy volunteers could be especially suitable for an HPV-specific cellular immunotherapy. Of note, vaccines contain HPV 16. To quantify HPV 16 E6-specific and E7-specific cells, enzyme-linked immunospot assays to measure interferon-γ (IFN-γ) and interleukin-10 (Th1-Th2 balance) and the secretion of the cytotoxic molecules granzyme B and perforin have been optimized. The frequency of peripheral blood mononuclear cells secreting IFN-γ and perforin was significantly (P<0.05) increased in HPV-vaccinated versus nonvaccinated volunteers. Overall, however, the median frequency of HPV 16-specific cells with a favorable secretion profile (Th1 balanced and cytotoxic) was low even in vaccinated volunteers (IFN-γ: 0.0018% and 0.0023%, perforin: 0.01% and 0.0087% for E6-specific and E7-specific cells, respectively). But some vaccinated volunteers showed up to 0.1% HPV-specific, IFN-γ or perforin-secreting cells. In conclusion, our data suggest that vaccinated volunteers are superior to nonvaccinated donors for HPV-specific cellular cancer immunotherapy. PMID:27548034

  14. Fate of pharmaceuticals in rivers: Deriving a benchmark dataset at favorable attenuation conditions.

    Science.gov (United States)

    Kunkel, Uwe; Radke, Michael

    2012-11-01

    Pharmaceutical residues are commonly detected organic micropollutants in the aquatic environment. Their actual fate in rivers is still incompletely understood as their elimination is highly substance specific and studies often report contradictory results. To elucidate the ceiling of attenuation rates of pharmaceuticals in rivers we carried out a study at a river with favorable conditions for the elimination of organic micropollutants. Experiments were carried out at a small stream in Germany. Composite samples were taken at both ends of a 12.5 km long river stretch located downstream of a sewage treatment plant and analyzed for 10 pharmaceuticals. Moreover, pore water samples were taken and in situ photolysis experiments at several sites within the river stretch were performed to assess the importance of these individual elimination mechanisms. Pharmaceutical concentration in the surface water at the first sampling site ranged from 3.5 ng L(-1) for propranolol to 1400 ng L(-1) for diclofenac. In comparison to carbamazepine which was used as persistent tracer, all other pharmaceuticals were attenuated along the river stretch. Their elimination was higher in a sunny, dry weather period (period I) compared to a period with elevated discharge after a heavy rainfall (period II). Overall, the measured elimination rates ranged from 25% for sulfamethoxazole (period II) to 70% for propranolol (period I). Photolysis was only a relevant elimination process for diclofenac and potentially also for sotalol; for these compounds phototransformation half-life times of some hours were determined in the unshaded parts of the river. Biotransformation in the sediments was also an important attenuation process since the concentrations of the other pharmaceuticals in the sediments decreased relative to carbamazepine with depth. For the chiral betablocker metoprolol this biotransformation was also confirmed by a decrease in the enantiomer fractionation from 0.49 at site A to 0.43 at

  15. TIMP-3 expression associates with malignant behaviors and predicts favorable survival in HCC.

    Directory of Open Access Journals (Sweden)

    Xuefeng Gu

    Full Text Available The tissue inhibitors of metalloproteinases (TIMPs are proteins that specifically inhibit the proteolytic activity of the matrix metalloproteinases (MMPs. TIMP-3, the only member of the TIMPs that can tightly bind to the extracellular matrix, has been identified as a unique tumor suppressor that demonstrates the ability to inhibit tumor angiogenesis, invasion, and metastasis. This study aimed to detect the expression of TIMP-3 in hepatocellular carcinoma (HCC and investigate the association between TIMP-3 expression and its clinicopathological significance in HCC patients. In the current study, reverse transcription-polymerase chain reaction (RT-PCR and Western blotting of HCC cell lines and one-step quantitative reverse transcription PCR (qPCR and immunohistochemistry (IHC analyses in HCC tissues were performed, to characterize the TIMP-3 expression. Kaplan-Meier survival and Cox regression analyses were utilized to evaluate the prognosis of 101 HCC patients. The results showed that the expression of TIMP-3 in HCC was significantly decreased relative to that of non-cancerous cells and tissues. Furthermore, the TIMP-3 expression was statistically associated with malignant behaviors of HCC, including portal vein invasion (p = 0.036 and lymph node metastasis (p = 0.030. Cox regression analysis revealed that TIMP-3 expression was an independent prognostic factor for disease-free survival (p = 0.039 and overall survival (p = 0.049. These data indicate that TIMP-3 expression is a valuable prognostic biomarker for HCC and that TIMP-3 expression suggests a favorable prognosis for HCC patients.

  16. Summary geologic report on the Missoula/Bitterroot Drilling Project, Missoula/Bitterroot Basins, Montana

    International Nuclear Information System (INIS)

    The objective of the drilling project was to obtain information to assess the favorability of the Tertiary sedimentary units in the Missoula and Bitterroot Valleys for uranium potential. The group of Montana Tertiary basins, including the Missoula and Bitterroot Basins, has been assigned a speculative uranium potential of 46,557 tons of U3O8 at $100/lb by the 1980 National Uranium Resource Evaluation report. The seven drill holes, two in the Missoula Valley and five in the Bitterroot Valley, verified observations made during surface studies and provided additional information about the subsurface that was previously unknown. No uranium was found, although of the two localities the Bitterroot Valley is the more favorable. Three stratigraphic units were tentatively identified on the basis of lithology: pre-Renova clastic units, Renova Formation equivalents, and Sixmile Creek Formation equivalents. Of the three, the Renova Formation equivalents in the Bitterroot Valley appear to be the most favorable for possible uranium occurrences and the pre-Renova clastic units the least favorable

  17. Trip report Rainwater Basin Nebraska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is a summary a trip to Rainwater Basin Wetland Management District in 1991, and focuses on the hydrology and soil habitat types. It is part of the...

  18. Allegheny County Basin Outlines Map

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This basins dataset was created to initiate regional watershed approaches with respect to sewer rehabilitation. If viewing this description on the Western...

  19. Sedimentary features and exploration targets of Middle Permian reservoirs in the SW Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Guoming Xu

    2015-11-01

    Full Text Available The exploration direction and targets for the large-scale Middle Permian gas reservoirs in the Sichuan Basin are hot spots and challenges in current exploration researches. The exploration successes of large gas field of Cambrian Longwangmiao Formation in Gaoshiti-Moxi region, Central Sichuan Basin, indicated that prospective sedimentary facies belt was the basis for the formation of large gas fields. In this paper, based on seismic data, outcrop data and drilling data, the tectonic framework and sedimentary features of the Middle Permian in the SW Sichuan Basin were comprehensively studied. The following conclusions were reached from the perspective of sedimentary facies control: (1 during the Middle Permian, this region was in shallow water gentle slope belts with high energy, where thick reef flat facies were deposited; (2 the basement was uplifted during Middle Permian, resulting in the unconformity weathering crust at the top of Maokou Formation due to erosion; the SW Sichuan Basin was located in the karst slope belt, where epigenic karstification was intense; and (3 reef flat deposits superimposed by karst weathering crust was favorable for the formation of large-scale reef flat karst reservoirs. Based on the combination of the resources conditions and hydrocarbon accumulation conditions in this region, it was pointed out that the Middle Permian has great potential of large-scale reef flat karst gas reservoir due to its advantageous geological conditions; the Middle Permian traps with good hydrocarbon accumulation conditions were developed in the Longmen Mountain front closed structural belt in the SW Sichuan Basin and Western Sichuan Basin depression slope belt, which are favorable targets for large-scale reef flat karst reservoirs.

  20. The multi-factor recombination and processes superimposition model for hydrocarbon accumulation: application to the Silurian in the Tarim Basin

    Institute of Scientific and Technical Information of China (English)

    Meng Qingyang; Pang Xiongqi; Gao Jianbo

    2008-01-01

    The multi-factor recombination and processes superimposition model for hydrocarbon accumulation is put forward in view of the hydrocarbon geological characteristics of multiple episodes of structural evolution, multiple sets of source-reservoir-seal assemblage, multiple cycles of hydrocarbon accumulation and multiple episodes of readjustment and reconstruction in the complex superimposed basins in China. It is a system including theories and methods that can help to predict favorable exploration regions. According to this model, the basic discipline for hydrocarbon generation, evolution and distribution in the superimposed basins can be summarized in multi-factor recombination, processes superimposition, multiple stages of oil filling and latest stage preservation. With the Silurian of the Tarim basin as an example, based on the reconstruction of the evolution history of the four factors (paleo-anticline,source rock, regional cap rock and kinematic equilibrium belt) controlling hydrocarbon accumulation,this model was adopted to predict favorable hydrocarbon accumulation areas and favorable exploration regions following structural destruction in three stages of oil filling, to provide guidance for further exploration of oil and gas in the Silurian of the Tarim basin.

  1. Sustaining Exploration in Mature Basins

    International Nuclear Information System (INIS)

    Exploration is a business like any other business driven by opportunity, resources and expectation of profit. Therefore, exploration will thrive anywhere the opportunities are significant, the resources are available and the outlook for profit (or value creation) is good. To sustain exploration activities anywhere, irrespective of the environment, there must be good understanding of the drivers of these key investment criteria. This paper will examine these investment criteria as they relate to exploration business and address the peculiarity of exploration in mature basin. Mature basins are unique environment that lends themselves a mix of fears, paradigms and realities, particularly with respect to the perception of value. To sustain exploration activities in a mature basin, we need to understand these perceptions relative to the true drivers of profitability. Exploration in the mature basins can be as profitable as exploration in emerging basins if the dynamics of value definition-strategic and fiscal values are understood by operators, regulators and co ventures alike. Some suggestions are made in this presentation on what needs to be done in addressing these dynamic investment parameters and sustaining exploration activities in mature basins

  2. «En favor de las víctimas de la guerra»

    Directory of Open Access Journals (Sweden)

    Robles Muñoz, Cristóbal

    2009-12-01

    Full Text Available Informal representation given to Cardinal Gomá in December 1936, sending Ildebrando Antoniutti as apostolic delegate in humanitarian mission in July, remained at its lowest level relations between the Holy See with the government of Franco. The situation changed in 1937. The nuncio Gaetano Cicognani did not arrive until June 1938. Discrete steps of a secret diplomacy advised in September 1937 to formalize the relationship, at its lowest. Antoniutti and Pablo de Churruca were named Responsible of Affairs, in Burgos, and to the Holy See, in a respective way. The collective letter of the bishops helped to improve the image of «national» Spain before the Catholics in other countries. The doctrinal position in which these facts were inserted was fixed at three encyclicals published in March 1937. They condemned the religious persecution of communism, nazism and the fear of a desire to runaway of the persecution forgiving people and fighting for justice for the working classesLa representación oficiosa dada al cardenal Gomá en diciembre de 1936, el envío Ildebrando Antoniutti como delegado apostólico en julio en misión humanitaria, mantuvieron bajo mínimos las relaciones de la Santa Sede con el Gobierno de Franco. La situación no cambió en 1937. El nuncio Gaetano Cicognani no llegó hasta junio de 1938. Los pasos discretos de una diplomacia secreta aconsejaron en septiembre de 1937 formalizar las relaciones, en su nivel más bajo. Antoniutti y Pablo de Churruca fueron nombrados encargados de negocios, en Burgos y ante la Santa Sede. La carta colectiva de los obispos ayudó a mejorar la imagen los nacionales ante los católicos de otros países. La posición doctrinal en que se insertan estos hechos quedó fijada en las tres encíclicas publicadas en marzo de 1937. En ella se denuncia la persecución religiosa del comunismo, el temor al nazismo y el deseo de salir de la persecución personando y luchando por la justicia a favor de las clases

  3. Favorable anatomic and visual outcomes with 25-gauge vitrectomy for myopic foveoschisis

    Directory of Open Access Journals (Sweden)

    Mii M

    2014-09-01

    Full Text Available Mei Mii, Masato Matsuoka, Kayako Matsuyama, Yayoi Otsu, Tetsuya Nishimura Department of Ophthalmology, Kansai Medical University, Takii Hospital, Osaka, Japan Purpose: To report the surgical outcomes of 25-gauge vitrectomy in eyes with myopic foveoschisis (MF. Methods: The medical records of 40 eyes of 36 patients that had undergone 25-gauge vitrectomy with internal limiting membrane peeling for MF were studied. The main outcome measures were the best-corrected visual acuity (BCVA and the optical coherence tomography (OCT findings. The eyes were divided into two groups: 1 those with a foveal detachment (FD; FD group; and 2 those without a FD (no-FD group. Results: The postoperative OCT images showed a resolution of the MF with a significant reduction in the central foveal thickness from the preoperative values in both the FD group (479±150 µm to 196±56 µm; P=0.002, mean ± standard deviation and in the no-FD group (369±116 µm to 245±50 µm; P=0.001. The final mean BCVA significantly improved from the preoperative values in the FD group (0.96±0.53 logarithm of the minimum angle of resolution [logMAR] units to 0.70±0.56 logMAR units; P=0.009 and in the no-FD group (0.46±0.38 logMAR units to 0.34±0.36 logMAR units; P=0.007. The final BCVA in the FD group improved in 63%, remained unchanged in 31%, and worsened in 6%. In the no-FD group, the final BCVA improved in 21%, remained unchanged in 71%, and worsened in 8% of the eyes. A better final BCVA was significantly correlated with a better preoperative BCVA in both groups (P<0.001. Conclusion: Twenty five-gauge vitrectomy results in favorable visual and anatomic outcomes for MF. We recommend that 25-gauge vitrectomy be used to treat eyes with MF. Keywords: myopic foveoschisis, 25-gauge vitrectomy, high myopia, internal limiting membrane, gas tamponade

  4. Aceleración de la enseñanza para alumnos superdotados: argumentos favorables y contrarios

    Directory of Open Access Journals (Sweden)

    Renata Rodrigues Maia-Pinto

    2012-06-01

    Full Text Available Learning acceleration for gifted students: Favorable and unfavorable argumentsThis paper analyzes acceleration in education as a practice for meeting the educational needs of gifted students, and points out favorable and unfavorable arguments on the use of this practice. Acceleration is an educational practice consisting of several teaching strategies designed to encourage academically gifted students and reduce their time spent in school. It promotes faster learning by matching the curriculum to the student’s level of knowledge, interest and motivation. There are several arguments in favor of acceleration, such as the improvement of academic performance, self-esteem and student’s social adjustment. However, educators are reluctant to implement this practice, arguing that students may be immature or lose part of the content of the regular curriculum.

  5. The Pliocene and Quaternary formations of El Abalario, in the Huelva province littoral (Spain); Las formaciones Plio-Cuaternarias de El Abalario, en el litoral de la provincia de Huelva (Espana)

    Energy Technology Data Exchange (ETDEWEB)

    Salvany, J.M.; Mediavilla, C.; Rebollo, A.

    2010-07-01

    The study of new and ancient boreholes in El Abalario area (Lower Guadalquivir basin) permitted to identify four main plio-quaternary formations above the Miocene marls, namely: Huelva Sands, Bonares Sands, Almonte Sands and Gravels, and El Abalario Sands. Respectively, they are interpreted as shallow marine, deltaic, alluvial and eolian sediments, together forming a marine to continental sequence that reaches a thickness of more than 250 metres. All sediments are arranged as a gentle dipping and thickening structure to the southeast. Only a few boreholes of the western border of El Abalario reach the top of the Miocene marls. In the rest of the Abalario area the Miocene marls are confined to an unknown level bellow the deepest boreholes. Upward, the marls grade to the Huelva sands, without any appreciable break in the sediments. To the north, the upper part of the Huelva formation grades to the Bonares sands, which is mainly developed outside the study area. Both formations are covered by the coarse clastic deposits of the Almonte formation. At the top, El Abalario sands recover all previous deposits and configure the current relief. This study improves the early existing geology profile and the connection with the surrounding areas (Author).

  6. Logging as a means of characterising the water in rock formations in groundwater collection borings; Utilizacion de diagrafias para la caracterizacion del agua de la formaciones en sondeos de captacion de aguas subterranea

    Energy Technology Data Exchange (ETDEWEB)

    Diaz Curiel, J.M.; Miguel, M.J.; Dominguez, S.; Caparrini, N

    1998-12-01

    We present an improvement of the S.P. application to obtain water conductivity and total of dissolved solids in the permeable layers passed through open hole, supposing said levels completely water saturated (under phreatic level). The optimization consists of a methodology for the treatment and interpretation of S.P. logs as well as the development of computer codes to execute the following processes. Laboratory measurements to acquire a set of key values in the interpretation processes (R{sub w}e/R{sub w} and TDS/R{sub w}). Conversion of the obtained data and selected charts, with continuous application range, to analytical curves for their automatic procedure. Algorithms development in order to carry out the automatic determination of base line and the elimination of its displacements. This system have been applied over a set of 27 logs performed by the author in the south area of the Duero basin (Spain) as an example of multi-layered detrital. We show the conductivity and TDS results in comparison with the water analysis obtained through pumping. (Author) 30 refs.

  7. Criteria for uranium occurrences in Saskatchewan and Australia as guides to favorability for similar deposits in the United States

    International Nuclear Information System (INIS)

    The objective of this study was to explain the occurrence of the large uranium deposits that have been found in northern Saskatchewan and the Northern Territory of Australia, to provide criteria to evaluate the favorability of Proterozoic rocks in the United States for similar deposits. All of these deposits belong to the class known as the Proterozoic unconformity-type pitchblende deposits. Chapters are devoted to: uranium deposits in Saskatchewan; uranium deposits of the Darwin and Arnhem Land area, Northern Territory of Australia; model for the Proterozoic unconformity-type pitchblende deposits; and evaluation of the geology of selected states for its favorability for Proterozoic unconformity-type pitchblende deposits

  8. Sustained favorable long-term outcome in the treatment of schizophrenia: a 3-year prospective observational study

    Directory of Open Access Journals (Sweden)

    Ascher-Svanum Haya

    2011-08-01

    Full Text Available Abstract Background This study of chronically ill patients with schizophrenia aimed to identify patients who achieve sustained favorable long-term outcome - when the outcome incorporates severity of symptoms, level of functioning, and use of acute care services - and to identify the best baseline predictors of achieving this sustained favorable long-term outcome. Methods Using data from the United States Schizophrenia Care and Assessment Program (US-SCAP (N = 2327, a large 3-year prospective, multisite, observational study of individuals treated for schizophrenia in the US, a hierarchical cluster analysis was performed to group patients based upon baseline symptom severity. Symptom severity was assessed using the Positive and Negative Syndrome Scale (PANSS scores, level of functioning, and use of acute care services. Level of functioning reflected patient-reported productivity and clinician-rated occupational role functioning. Use of acute care services reflected self-reported psychiatric hospitalization and emergency service use. Change of health state was determined over the 3-year period. A patient was classified as having a sustained favorable long-term outcome if their health state values had the closest distance to the defined "best baseline cluster" at each point over the length of the study. Stepwise logistic regression was used to determine baseline predictors of sustained favorable long-term outcome. Results At baseline, 5 distinct health state clusters were identified, ranging from "best" to "worst." Of 1635 patients with sufficient data, only 157 (10% experienced sustained favorable long-term outcome during the 2-years postbaseline. The baseline predictors associated with sustained favorable long-term outcome included better quality of life, more daily activities, patient-reported clearer thinking from medication, better global functioning, being employed, not being a victim of a crime, not having received individual therapy, and not

  9. Preferential uptake of ribose by primitive cells might explain why RNA was favored over its analogs

    Science.gov (United States)

    Pohorille, Andrew; Wei, Chenyu

    perme-ation, even though it is non-negligibly populated in aqueous solution. The differences in free energy barrier between ribose and arabinose or xylose are due to stronger, highly cooperative, intramolecular interactions between consecutive exocyclic hydroxyl groups, which are stable in non-polar media, but rare in water. Most recently, we extended calculations of permeations to ribonucleosides and their anomers. We determined that, in contrast to sugars, permeation of membranes to these species is nearly identical. This is because sugars of nucleotides exist in the furanose rather than pyranose form. In this form intermolecular interactions between hydroxyl groups are not nearly as efficient for sterical reasons. Our results contribute to the discussion about autotrophic vs. heterotrophic origins of life. Chemical reactions inside protobiological vesicle required supply of organic material from the environment. What was the inventory of organics that must have been delivered to primitive cells is still being debated. According to the autotrophic hypothesis, ancestors of cells pro-duced complex organic molecules from simple substrates. In contrast, the heterotrophic model implies that protocells were able to utilize complex organics delivered from external sources. A possibility of sufficiently efficient uptake of molecules needed to build biopolymers provides an important argument supporting the heterotrophic hypothesis [3]. Viewed in the context of the "RNA world" hypothesis [4], which states that RNA molecules were the first biological poly-mers and acted as both catalysts of biochemical reactions and information storage systems, our results demonstrate that, in the absence of sophisticated mechanisms available to contemporary organisms for achieving selectivity during synthesis and transmembrane transport, preferential uptake of ribose by primitive cells might have provided a kinetic mechanism that favored its selective incorporation into nucleic acids and

  10. Tax Breaks for Parents of Private School Students: Who Favors Them and Who Would Take Advantage of Them?

    Science.gov (United States)

    Bezdek, Robert; Cross, Ray

    1983-01-01

    A sample of Corpus Christi, Texas, citizens were interviewed for their views on granting income tax breaks to parents of private school students. Results indicate that, while low-income Hispanics are most in favor of the tax breaks, upper income Anglos are most likely to take advantage of them. (KH)

  11. Asymmetric C-C Bond-Formation Reaction with Pd: How to Favor Heterogeneous or Homogeneous Catalysis?

    DEFF Research Database (Denmark)

    Reimann, S.; Grunwaldt, Jan-Dierk; Mallat, T.;

    2010-01-01

    clear deviation from the behavior of the corresponding homogeneous system. In contrast, halogenated solvents are easily dehalogenated on Pd/Al2O3 and thus they favor leaching of the metal and formation of soluble compounds, analogous to classical metal corrosion in the presence of halide ions. The...

  12. Development of intelligent model to determine favorable wheelchair tilt and recline angles for people with spinal cord injury.

    Science.gov (United States)

    Fu, Jicheng; Jan, Yih-Kuen; Jones, Maria

    2011-01-01

    Machine-learning techniques have found widespread applications in bioinformatics. Such techniques provide invaluable insight on understanding the complex biomedical mechanisms and predicting the optimal individualized intervention for patients. In our case, we are particularly interested in developing an individualized clinical guideline on wheelchair tilt and recline usage for people with spinal cord injury (SCI). The current clinical practice suggests uniform settings to all patients. However, our previous study revealed that the response of skin blood flow to wheelchair tilt and recline settings varied largely among patients. Our finding suggests that an individualized setting is needed for people with SCI to maximally utilize the residual neurological function to reduce pressure ulcer risk. In order to achieve this goal, we intend to develop an intelligent model to determine the favorable wheelchair usage to reduce pressure ulcers risk for wheelchair users with SCI. In this study, we use artificial neural networks (ANNs) to construct an intelligent model that can predict whether a given tilt and recline setting will be favorable to people with SCI based on neurological functions and SCI injury history. Our results indicate that the intelligent model significantly outperforms the traditional statistical approach in accurately classifying favorable wheelchair tilt and recline settings. To the best of our knowledge, this is the first study using intelligent models to predict the favorable wheelchair tilt and recline angles. Our methods demonstrate the feasibility of using ANN to develop individualized wheelchair tilt and recline guidance for people with SCI. PMID:22254738

  13. The Bias in Favor of Venture Capital Finance in U.S. Entrepreneurial Education: At the Expense of Trade Credit

    Science.gov (United States)

    Clement, Thomas; LeMire, Steven; Silvernagel, Craig

    2015-01-01

    The authors examine whether U.S. college-level entrepreneurship education demonstrates a bias favoring venture capital (VC) financing while marginalizing trade credit financing, and the resulting impact on entrepreneurship students. A sample of U.S. business textbooks and survey data from entrepreneurship students reveals a significant bias toward…

  14. Hydrocarbon habitat in rifted basins

    Energy Technology Data Exchange (ETDEWEB)

    Ziegler, P.A. [Basel Univ. (Switzerland)

    1996-12-01

    Tectonically active rifts, palaeo-rifts and passive margin basins contain major hydrocarbon provinces. Their hydrocarbon charge can rely exclusively on pre-rift, syn-rift sedimentary sequences or a combination thereof. Maturation of source-rocks can be achieved during the syn-and/or post-rift stage of basin evolution. During rifting, conductive and convective heat transfer accounts for elevated geothermal gradients; these play an important role in the maturation of pre- and syn-rift source-rocks; as geothermal gradients decrease asymptotically during the post-rift stage, maturation of late syn- and post-rift source-rocks depends on massif overburden thicknesses. In most rift structuration and trap-formation predate or are contemporaneous with peak oil and gas generation. Post-rift subsidence and stress-induced basin tilting or inversion can cause modification of trap configurations, causing loss of hydrocarbons. (author). 58 refs., 1 fig., 1 tab.

  15. Effect of edaravone on favorable outcome in patients with acute cerebral large vessel occlusion: subanalysis of RESCUE-Japan Registry.

    Science.gov (United States)

    Miyaji, Yuki; Yoshimura, Shinichi; Sakai, Nobuyuki; Yamagami, Hiroshi; Egashira, Yusuke; Shirakawa, Manabu; Uchida, Kazutaka; Kageyama, Hirohito; Tomogane, Yusuke

    2015-01-01

    The data of the nationwide prospective registry of acute cerebral large vessel occlusion (LVO; RESCUE-Japan Registry) were analyzed to know the effect of edaravone, a free radical scavenger, on clinical outcome at 90 days after onset. In this registry, patients with acute cerebral LVO admitted within 24 h after onset were prospectively registered. The effect of various factors including endovascular treatment (EVT), intravenous recombinant tissue plasminogen activator (IV rt-PA), and other medication including edaravone on favorable outcome (modified Rankin scale 0-1) was analyzed. Of the 1,454 registered patients, 1,442 patients (99.2%) had the information of edaravone were analyzed. In total, edaravone group had more patients with favorable outcome compared to non-edaravone group (22.9% vs. 13.8%, p = 0.0006). Edaravone increased favorable outcome in patients treated with IV rt-PA (29.4% vs. 11.1%, p = 0.0107), but not with EVT (21.2% vs. 13.9%, p = 0.309). Logistic regression analysis revealed that higher National Institutes of Health Stroke Scale (NIHSS) score on admission [odds ratio (OR) 0.875, 95% confidence interval (CI) 0.858-0.894] and advanced age (OR 0.963, 95%CI 0.952-0.975) were significantly related to unfavorable outcome. In contrast, IV rt-PA (OR 2.489, 95%CI 1.867-3.319), EVT (OR 1.375, 95%CI 1.013-1.865), and edaravone (OR 1.483, 95%CI 1.027-2.143) were significantly associated with favorable outcome. This analysis indicated that IV rt-PA, EVT, and edaravone were effective to obtain favorable outcome in patients with acute LVO. Combination IV rt-PA with edaravone was more effective. PMID:25739433

  16. Geology, exploration status of Uruguay's sedimentary basins

    Energy Technology Data Exchange (ETDEWEB)

    Goso, C.; Santa Ana, H. de (Administracion Nacional de Combustibles, Alcohol y Portland (Uruguay))

    1994-02-07

    This article attempts to present the geological characteristics and tectonic and sedimentary evolution of Uruguayan basins and the extent to which they have been explored. Uruguay is on the Atlantic coast of South America. The country covers about 318,000 sq km, including offshore and onshore territories corresponding to more than 65% of the various sedimentary basins. Four basins underlie the country: the Norte basin, the Santa Lucia basin, the offshore Punta del Este basin, and the offshore-onshore Pelotas-Merin basin. The Norte basin is a Paleozoic basin while the others are Mesozoic basins. Each basin has been explored to a different extent, as this paper explains.

  17. WATSTORE Stream Flow Basin Characteristics File

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Stream Flow Basin Characteristics file contains information about the drainage basins of selected USGS gaging stations. Data elements of this file were...

  18. Origin of the earth's ocean basins

    Science.gov (United States)

    Frey, H.

    1977-01-01

    The earth's original ocean basins are proposed to be mare-type basins produced 4 billion y.a. by the flux of asteroid-sized objects responsible for the lunar mare basins. Scaling upward from the observed number of lunar basins for the greater capture cross-section and impact velocity of the earth indicates that at least 50% of an original global crust would have been converted to basin topography. These basins were flooded by basaltic liquids in times short compared to the isostatic adjustment time for the basin. The modern crustal dichotomy (60% oceanic, 40% continental crust) was established early in the history of the earth, making possible the later onset of plate tectonic processes. These later processes have subsequently reworked, in several cycles, principally the oceanic parts of the earth's crust, changing the configuration of the continents in the process. Ocean basins (and oceans themselves) may be rare occurrences on planets in other star systems.

  19. Local Wave Propagation in the Kachchh Basin, India: Synergy With the New Madrid Seismic Zone

    Science.gov (United States)

    Langston, C. A.; Kang, D.; Bodin, P.; Horton, S.

    2002-12-01

    Aftershocks of the Mw7.6 Bhuj earthquake are used to infer velocity structure and the nature of wave propagation within the Kachchh Basin, India. The data were collected from a joint MAEC/ISTAR deployment of seismographs within 3 weeks of the main event and from existing broadband stations in the region under the India Meteorological Department. Waveforms are available from events that span the entire thickness of the crust and display a variety of wave propagation effects due to low-velocity near-surface site structure and larger structure of the Mesozoic Kachchh basin. These effects include near-site, high frequency reverberations in P and S waves, Sp and Ps mode conversions, PL waves within the Mesozoic basin, basin S multiples, and surface waves. Surface wave group velocity dispersion yields estimates of basin shear wave velocity, and when coupled to analysis of large observed Sp conversions, give a migrated image of stratigraphy within the Banni plains that agrees favorably with published stratigraphy. Identification of basin structure effects allows constraints to be placed on aftershock source depths that are needed in evaluating standard earthquake locations. Structure models are used to construct Green's functions for determining source parameters through waveform modeling. Although stations of the aftershock network were situated on a variety of sites that varied from consolidated Mesozoic bedrock to unconsolidated recent sediments, all stations show major wave propagation effects due to basin fill that must be included in source parameter estimation. These effects seen in India have many similarities to wave propagation effects observed within the Mississippi embayment from microearthquakes in the New Madrid Seismic Zone (NMSZ) of the central U.S. Joint waveform studies are motivating new ways of understanding wave propagation and source processes within both areas.

  20. Krušné hory Piedmont basins. Sokolov Basin

    Czech Academy of Sciences Publication Activity Database

    Rojík, P.; Dašková, Jiřina; Kvaček, Z.; Pešek, J.; Sýkorová, Ivana; Teodoridis, V.

    Prague: Czech Geological Survey, 2014, s. 90-142 ISBN 978-80-7075-862-5 R&D Projects: GA ČR GA105/06/0653 Institutional support: RVO:67985891 ; RVO:67985831 Keywords : Tertiary basins * Czech Republic * Cenomanian and Tertiary lignite * geology * stratigraphy Subject RIV: DB - Geology ; Mineralogy

  1. Supplementary information on K-Basin sludges

    Energy Technology Data Exchange (ETDEWEB)

    MAKENAS, B.J.

    1999-03-15

    Three previous documents in this series have been published covering the analysis of: K East Basin Floor and Pit Sludge, K East Basin Canister Sludge, and K West Basin Canister Sludge. Since their publication, additional data have been acquired and analyses performed. It is the purpose of this volume to summarize the additional insights gained in the interim time period.

  2. Supplementary information on K-Basin sludges

    International Nuclear Information System (INIS)

    Three previous documents in this series have been published covering the analysis of: K East Basin Floor and Pit Sludge, K East Basin Canister Sludge, and K West Basin Canister Sludge. Since their publication, additional data have been acquired and analyses performed. It is the purpose of this volume to summarize the additional insights gained in the interim time period

  3. New bifurcations of basin boundaries involving Wada and a smooth Wada basin boundary

    Institute of Scientific and Technical Information of China (English)

    Zou Hai-Lin; Xu Jian-Xue; Jiang Jun

    2008-01-01

    This paper demonstrates and analyses double heteroclinic tangency in a three-well potential model,which can produce three new types of bifurcations of basin boundaries including from smooth to Wada basin boundaries,from fractal to Wada basin boundaries in which no changes of accessible periodic orbits happen,and from Wada to Wada basin boundaries.In a model of mechanical oscillator,it shows that a Wada basin boundary can be smooth.

  4. Prospect analysis for sandstone-type uranium mineralization in the northern margin of Qaidam basin

    International Nuclear Information System (INIS)

    Affected by the regional geological structural evolution, a set of sedimentary structure, i.e. the construction of coal-bearing classic rocks which is in favor of the sandstone-type uranium mineralization has deposited in the northern margin of Qaidam Basin since Meso-Cenozoic. A NWW thrust nappe tectonic belt, i.e. the ancient tectonic belt which is the basis for the development of ancient interlayer oxidation zone formed by the tectonic reverse in late Jurassic and Cretaceous. The Mid and late Jurassic layer was buried by the weak extension in Paleogene and the depression in early Neogene. The extrusion reversal from late Neogene to Quaternary made the basin into the development era of the modern interlayer oxidation zone. It can be concluded that the layer of the northern margin of Qaidam Basin has the premise for the formation of sandstone-type uranium ore. Based on the analysis of the characteristics of the thrust belt, the structure of the purpose layer, the sand body, the hydrogeology, the interlayer oxidation zone and uranium mineralization, the results indicated that the ancient interlayer oxidation zone is the prospecting type of sandstone-type uranium ore. Beidatan and the east of Yuqia are the favorable prospective area of sandstone-type uranium mineralization. (authors)

  5. The Mackenzie Basin impacts study

    International Nuclear Information System (INIS)

    In 1989, a commitment was made to begin development of a framework for an integrated regional impact assessment of global warming scenarios in the Mackenzie Basin, the most populated region of Canada's north. The project, called Mackenzie Basin Impact Study (MBIS), is led by a multidisciplinary working group from government and non-governmental organizations with interests in the Basin. Objectives of MBIS include defining the direction and magnitude of regional-scale impacts of global warming scenarios on the physical, biological, and human systems of the Basin. MBIS will also identify regional sensitivities to climate, inter-system linkages, uncertainties, policy implications, and research needs. MBIS research activities as of March 1992 are outlined and policy concerns related to global warming are listed. Two new methodologies are being developed by MBIS to address particular economic and policy concerns: a socio-economic resource accounting framework and an integrated land assessment framework. Throughout MBIS, opportunities will be presented for western science and traditional native knowledge to be integrated

  6. From channelization to restoration: Sociohydrologic modeling with changing community preferences in the Kissimmee River Basin, Florida

    Science.gov (United States)

    Chen, Xi; Wang, Dingbao; Tian, Fuqiang; Sivapalan, Murugesu

    2016-02-01

    The Kissimmee River Basin (Florida, USA) underwent river channelization in the 1960s and subsequent restoration in the 1990s, revealing a shift in management emphasis from flood protection to wetland health. In this paper, this shift is hypothesized to result from changing human values and preferences, and a power differential between the more numerous and affluent upstream urban residents (who prioritize wetland restoration) and downstream rural residents (who prioritize flood protection). We develop a conceptual sociohydrologic model to simulate the interactions between community interests and hydrology. The modeling results show that flood intensity decreased after channelization, which reduced concern about flooding. However, channelization also led to a decrease in wetland storage, which caused an increase of wetland concern, especially among the urban residents. Eventually, the community sensitivity switched from favoring flood protection to favoring wetlands, and subsequent management strategies switched from channelization to restoration. Using the model, we project that the wetlands will be recovering for the next 20 years and community sensitivity will slowly go back to a neutral state. However, possible rainfall intensification in the future could return the community sensitivity to favoring flood protection again. The preferential increase of upstream population growth will raise the community's concern about wetlands and the preferential increase of downstream population growth will magnify concern about flooding. This study provides insight into the driving forces behind human-water interactions in the Kissimmee River Basin while simultaneously demonstrating the potential of sociohydrologic modeling to describe complex human-water coupled systems with simple concepts and equations.

  7. Uranium mineralization rules controlled by sedimentation in Bayanwula region in Erlian basin

    International Nuclear Information System (INIS)

    Uranium mineralization is closely related to sedimentation in Bayanwula region in Erlian Basin. Clarifying the relation of sedimentation and Uranium Mineralization Through detailed analysis of vertical sequences, stratigraphic correlation and the heterogeneity of sand body. Study show that the of development characteristics of sequences of Bayanwula region control the vertical positioning of favorable sand, the skeleton sand bodies of LST in upper Saihan formation is the most favorable reservoir space for uranium. Uranium mineralization is closely related with the heterogeneity of the sand bodies of upper Saihan formation. the heterogeneity of Sand body is mainly reflected in plane and vertical. In plane, with the research of the sand distributed system of upper Saihan formation, the change position of sandstone thickness and sand rate, the position of the variation of shape and trend of sand body, and the change position of sand body character and genesis are most favorable for uranium mineralization. In vertical, the number of layers and thickness of isolated barrier bed not only control the thickness of oxide sandstone. but also they are associated with the distribution of uranium mineralization; The evolution of sedimentary basins created Bayanwula uranium deposits. There is a second order sequence boundary between the upper Saihan formation and the Erlian formation of Late Cretaceous, which is a long-term exposure and erosion unconformity, resulting in the partly erosion of the upper Saihan formation, providing the best conditions of the penetration of the uranium-bearing oxygen water and the development of phreatic oxidation and interlayer oxidation zone. (author)

  8. Reinterpretacion estratigráfica y petrología de la Formacion Chuscho, Precordillera de La Rioja Stratigraphical reinterpretation and petrology of the Cerro Chuscho Formation. Precordillera of La Rioja

    Directory of Open Access Journals (Sweden)

    L.E. Fauqué

    2003-06-01

    , sills and pillow-lavas of basaltic composition, representing an ophiolitic facies interbedded in the sedimentary pile. The Cerro Chuscho Formation belongs to the "Famatinian Ophiolitic Belt", which is related to the opening of a marginal basin during Chilenia accretion in Cambro-Ordovician times. The geochemical signature of the basaltic rocks changes along the rift, from N-MORB in the Cordillera Frontal to E-MORB in the Precordillera of San Juan and La Rioja. This variation probably reflects the changing altitude of the rift relative to the mantle. By contrast, the "Andesitas Punta del Agua", of Late Carboniferous to Early Permian age, are considered to be subduction-related andesites according to their geochemical characteristics.

  9. Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease.

    Science.gov (United States)

    Yaghootkar, Hanieh; Lotta, Luca A; Tyrrell, Jessica; Smit, Roelof A J; Jones, Sam E; Donnelly, Louise; Beaumont, Robin; Campbell, Archie; Tuke, Marcus A; Hayward, Caroline; Ruth, Katherine S; Padmanabhan, Sandosh; Jukema, J Wouter; Palmer, Colin C; Hattersley, Andrew; Freathy, Rachel M; Langenberg, Claudia; Wareham, Nicholas J; Wood, Andrew R; Murray, Anna; Weedon, Michael N; Sattar, Naveed; Pearson, Ewan; Scott, Robert A; Frayling, Timothy M

    2016-08-01

    Recent genetic studies have identified some alleles that are associated with higher BMI but lower risk of type 2 diabetes, hypertension, and heart disease. These "favorable adiposity" alleles are collectively associated with lower insulin levels and higher subcutaneous-to-visceral adipose tissue ratio and may protect from disease through higher adipose storage capacity. We aimed to use data from 164,609 individuals from the UK Biobank and five other studies to replicate associations between a genetic score of 11 favorable adiposity variants and adiposity and risk of disease, to test for interactions between BMI and favorable adiposity genetics, and to test effects separately in men and women. In the UK Biobank, the 50% of individuals carrying the most favorable adiposity alleles had higher BMIs (0.120 kg/m(2) [95% CI 0.066, 0.174]; P = 1E-5) and higher body fat percentage (0.301% [0.230, 0.372]; P = 1E-16) compared with the 50% of individuals carrying the fewest alleles. For a given BMI, the 50% of individuals carrying the most favorable adiposity alleles were at lower risk of type 2 diabetes (odds ratio [OR] 0.837 [0.784, 0.894]; P = 1E-7), hypertension (OR 0.935 [0.911, 0.958]; P = 1E-7), and heart disease (OR 0.921 [0.872, 0.973]; P = 0.003) and had lower blood pressure (systolic -0.859 mmHg [-1.099, -0.618]; P = 3E-12 and diastolic -0.394 mmHg [-0.534, -0.254]; P = 4E-8). In women, these associations could be explained by the observation that the alleles associated with higher BMI but lower risk of disease were also associated with a favorable body fat distribution, with a lower waist-to-hip ratio (-0.004 cm [95% CI -0.005, -0.003] 50% vs. 50%; P = 3E-14), but in men, the favorable adiposity alleles were associated with higher waist circumference (0.454 cm [0.267, 0.641] 50% vs. 50%; P = 2E-6) and higher waist-to-hip ratio (0.0013 [0.0003, 0.0024] 50% vs. 50%; P = 0.01). Results were strengthened when a meta-analysis with five additional studies was conducted

  10. Structural investigations of Great Basin geothermal fields: Applications and implications

    Energy Technology Data Exchange (ETDEWEB)

    Faulds, James E [Nevada Bureau of Mines and Geology, Univ. of Nevada, Reno, NV (United States); Hinz, Nicholas H. [Nevada Bureau of Mines and Geology, Univ. of Nevada, Reno, NV (United States); Coolbaugh, Mark F [Great Basin Center for Geothermal Energy, Univ. of Nevada, Reno, NV (United States)

    2010-11-01

    Because fractures and faults are commonly the primary pathway for deeply circulating hydrothermal fluids, structural studies are critical to assessing geothermal systems and selecting drilling targets for geothermal wells. Important tools for structural analysis include detailed geologic mapping, kinematic analysis of faults, and estimations of stress orientations. Structural assessments are especially useful for evaluating geothermal fields in the Great Basin of the western USA, where regional extension and transtension combine with high heat flow to generate abundant geothermal activity in regions having little recent volcanic activity. The northwestern Great Basin is one of the most geothermally active areas in the USA. The prolific geothermal activity is probably due to enhanced dilation on N- to NNE-striking normal faults induced by a transfer of NW-directed dextral shear from the Walker Lane to NW-directed extension. Analysis of several geothermal fields suggests that most systems occupy discrete steps in normal fault zones or lie in belts of intersecting, overlapping, and/or terminating faults. Most fields are associated with steeply dipping faults and, in many cases, with Quaternary faults. The structural settings favoring geothermal activity are characterized by subvertical conduits of highly fractured rock along fault zones oriented approximately perpendicular to the WNW-trending least principal stress. Features indicative of these settings that may be helpful in guiding exploration for geothermal resources include major steps in normal faults, interbasinal highs, groups of relatively low discontinuous ridges, and lateral jogs or terminations of mountain ranges.

  11. Birth Weight, Birth Length, and Gestational Age as Indicators of Favorable Fetal Growth Conditions in a US Sample

    OpenAIRE

    Camerota, Marie; Bollen, Kenneth A.

    2016-01-01

    The “fetal origins” hypothesis suggests that fetal conditions not only affect birth characteristics such as birth weight and gestational age, but also have lifelong health implications. Despite widespread interest in this hypothesis, few methodological advances have been proposed to improve the measurement and modeling of fetal conditions. A Statistics in Medicine paper by Bollen, Noble, and Adair examined favorable fetal growth conditions (FFGC) as a latent variable. Their study of Filipino ...

  12. Policies in favor of the bicycle development.; Politiques en faveur du developpement du velo. Bonnes pratiques de villes europeennes

    Energy Technology Data Exchange (ETDEWEB)

    Vallar, J.P.; Kerveillan, A.

    2001-07-01

    This study presents, ten cases of european towns which realized a policy in favor of the bicycle development. With the incitation to the displacement on foot and the public transportation, it is a good and efficient way of environmental quality. For each case, the following points are presented: global policy of the local government, technical aspects and organization, economic, environmental aspects and behavior, future orientations and contacts. (A.L.B.)

  13. More Favorable and Differential Treatment of Developing Countries : Toward a New Approach in the World Trade Organization

    OpenAIRE

    Hoekman, Bernard; Michalopoulos, Constantine; Winters, L. Alan

    2003-01-01

    The authors discuss options that could be considered in the World Trade Organization (WTO) to provide more favorable treatment-so-called special and differential treatment (SDT)-to small and low-income countries. They argue that there is a need both for differentiation across WTO members and for steps that would benefit all developing countries. The authors suggest the following to make th...

  14. Les entreprises moyennes cotées en bourse : de bonnes performances en 2011 mais moins favorables en 2012.

    OpenAIRE

    CAYSSIALS, J.-L.

    2013-01-01

    Les entreprises moyennes cotées en bourse enregistrent de bonnes performances en 2011 mais leurs marges se stabilisent, prémices d’un exercice 2012 moins favorable. L’investissement reste soutenu et la structure financière solide. La dégradation de l’environnement en 2012 et l’impact des normes comptables IFRS pourraient peser sur les comptes de 2012.

  15. Plasmodium falciparum induces a Th1/Th2 disequilibrium, favoring the Th1-type pathway, in the human placenta

    OpenAIRE

    Fievet, Nadine; Moussa, M.; Tami, G.; Maubert, B.; Cot, Michel; Deloron, P.; Chaouat, G.

    2001-01-01

    During pregnancy, a local and systemic Th2 bias of maternal immunity favors Th1-dependent infections such as malaria. This study measured cytokines secreted in cultures of chorionic villi, placental blood cells (PBC), and serum in term placentas from 88 malaria-infected and -noninfected Cameroon women. Interleukin (IL)-2 and-4 were consistently low ; IL-1Beta, IL-6, granulocyte-macrophage colony-stimulating factor, and transforming growth factor (TGF)-Beta2 were highest in PBC cultures. Malar...

  16. J-ACT II. Differences in rate of valid recanalization and of a favorable outcome by site of MCA occlusion

    International Nuclear Information System (INIS)

    The background and purpose of this study was to elucidate whether the effects of alteplase differ with occlusion site of the middle cerebral artery (MCA). An exploratory analysis was made of 57 patients enrolled on the Japan Alteplase Clinical Trial II (J-ACT II). The residual vessel length (mm), determined on pretreatment MR angiography (MRA), was used to reflect the occluded site. The proportions of patients with valid recanalization (modified Mori grade 2-3) at 6 and 24 hours, and a favorable outcome (modified Rankin scale 0-1 at 3 months) were compared between the groups dichotomized according to their lengths of residual vessel. Multiple logistic regression models were generated to elucidate the predictors of valid recanalization and a favorable outcome. Receiver operating characteristic (ROC) analysis revealed that 5 mm was the practical cutoff length for the dichotomization. In patients with M1 length <5 mm (n=12), the frequencies of valid recanalization at 6/24 hours (16.6%/25.0%) were significantly low compared with those (62.2%/82.2%) of 45 patients with a residual M1 length of ≥5 mm and M2 occlusions (p=0.008 for 6 hours, p<0.001 for 24 hours). The proportion of a favorable outcome was also small in patients with M1 length <5 mm (8.3%), as compared to the others (57.8%, p=0.004). In logistic regression models, the site of MCA occlusion (<5 mm) was the significant predictor of valid recanalization at 6/24 hours and of a favorable outcome. In patients with acute MCA occlusion, residual vessel length <5 mm on MRA can identify poor responders. (author)

  17. One-Step Targeted Minimum Loss-based Estimation Based on Universal Least Favorable One-Dimensional Submodels

    Science.gov (United States)

    van der Laan, Mark; Gruber, Susan

    2016-01-01

    Consider a study in which one observes n independent and identically distributed random variables whose probability distribution is known to be an element of a particular statistical model, and one is concerned with estimation of a particular real valued pathwise differentiable target parameter of this data probability distribution. The targeted maximum likelihood estimator (TMLE) is an asymptotically efficient substitution estimator obtained by constructing a so called least favorable parametric submodel through an initial estimator with score, at zero fluctuation of the initial estimator, that spans the efficient influence curve, and iteratively maximizing the corresponding parametric likelihood till no more updates occur, at which point the updated initial estimator solves the so called efficient influence curve equation. In this article we construct a one-dimensional universal least favorable submodel for which the TMLE only takes one step, and thereby requires minimal extra data fitting to achieve its goal of solving the efficient influence curve equation. We generalize these to universal least favorable submodels through the relevant part of the data distribution as required for targeted minimum loss-based estimation. Finally, remarkably, given a multidimensional target parameter, we develop a universal canonical one-dimensional submodel such that the one-step TMLE, only maximizing the log-likelihood over a univariate parameter, solves the multivariate efficient influence curve equation. This allows us to construct a one-step TMLE based on a one-dimensional parametric submodel through the initial estimator, that solves any multivariate desired set of estimating equations. PMID:27227728

  18. Asociaciones palinológicas en las formaciones Los Monos (Devónico) e Itacua (Carbonífero Inferior) en Balapuca (Cuenca Tarija), sur de Bolivia: Parte 1. Formación Los Monos Palynological assemblages present in Los Monos (Devonian) and Itacua (Lower Carboniferous) formations at Balapuca (Tarija basin), southern Bolivia: Part One. Los Monos Formation

    OpenAIRE

    Mercedes di Pasquo

    2007-01-01

    Se caracterizan cuali-cuantitativamente dos asociaciones palinológicas recuperadas de ocho muestras fértiles de la Formación Los Monos (Eifeliano tardío-Frasniano temprano), expuesta en la localidad de Balapuca, ubicada en la margen boliviana del río Bermejo en la sierra de San Telmo. Esta unidad depositada en la Cuenca Tarija, sobreyace a la Formación Pescado (o Huamampampa, Emsiano-Eifeliano), y subyace, cuando está preservada, a la Formación Iquirí (Frasniano-Famenniano). La sección litoló...

  19. Oil source rocks in sedimentary basins of the CIS

    Energy Technology Data Exchange (ETDEWEB)

    Neruchev, S. (VNIGRI, St. Petersburg (Russian Federation))

    1993-09-01

    Oil source rocks with dominant kerogen of types I or II and a concentration of organic carbon of 6-7% are widely distributed at specific stratigraphic levels in the Phanerozoic section of the world and control the petroleum richness of the main productive basins. Nineteen stratigraphic levels of source rock distribution have been identified and almost all of these stratigraphic levels are found in basins of the Commonwealth of Independent States. This paper contains a review of their distribution. Black shales and oil shales enriched by P, U, V, Mo, and, occasionally, by Ir, Os and other metals, are found in the same stratigraphic intervals outside petroleum basins. High concentrations of uranium have been identified in terrestrial rocks at several of the stratigraphic intervals. A high concentration of kerogen in oil source rocks is commonly explained by depositional conditions (anoxia and upwelling) that favor accumulation and preservation of organic matter. However, the main factor determining organic matter enrichment of sediments is rifting activity and its associated increase in phosphorus, radioactive elements and heavy metals. This results in ecological crises and global blossoming of plankton (cianobacteria, green algae, zooplankton in the Silurian and diatoms in the Miocene). Rocks with increased concentrations of radioactive elements are present at the boundaries of large stratigraphic units that can be identified by paleontologic data. These rocks mark major events of fauna extinction and other important biotic events. The periodicity of the major global events is about 220 m.y., which corresponds to duration of the galactic year. Smaller periodicity of about 30 m.y. is identified inside the major periods. These regularities in the organic-rich rock distribution can be used to predict the presence of oil source rocks, oil shales, and shales enriched by metals.

  20. Structural geology of Ordos basin mineralization and mineralization of uranium deposits in the Huianbao region, west of Ordos basin

    International Nuclear Information System (INIS)

    The thesis discussed the geotectonic setting of west Ordos Basin, classification of tectonic units, geology of west fault-fold belt and structural feature in Majiatan region. The stable tectonic region was overall guidance thoughts and ideas for the uranium deposits in the structure relative activities region. Based on exploration and research of uranium geology for many years, the over-thrust nappe belt was favorable region for uranium mineralization. Two oxidation layers which the ancient oxidation was red and oxidation alteration was yellow existed in this region, the uranium ore was controlled on by two oxidation layers. Early red oxidized sandstone was experienced post-reformation such as thrust pushover, lifting, erosion, superimposed depth and separation of block fault. Late yellow oxidation which tended to inherit the early red oxidation and carry on the superposition modification distributed both wings of anticline. The thesis was to summarized the uranium features and metallogenic regularity, which has some guidance for uranium deposits in the basin. (authors)

  1. Cost-effectiveness assessment of transactions international water basins. an application to the andalusian Mediterranean basins; Valoracion coste eficacia de las transacciones de agua inter cuencas. Una aplicacion a las cuencas mediterraneas andaluzas

    Energy Technology Data Exchange (ETDEWEB)

    Olmedilla Perez, S.

    2011-07-01

    The purpose of this study is to evaluate through a cost-effectiveness approach water use transactions implemented under Water law framework. These measures complement others proposed by Water Plan of the Mediterranean-andallucian Basin. This water transfers were planned in order to improve the environmental conditions of the water body belonging to low Basin of almanzora river . The analysis was developed including uncertainty related with the availability of resources under various water scarcity scenarios. The results show that water use transactions, from a cost effectiveness approach, has a more favorable assessment than the measures which are explicitly outlined in the river Basin Plan. Furthermore, the study also incorporates a reflection about the suitability of this approach in front of others that consider not just the economic costs, but also others variables, such as social and environmental cost concerned in implementing such measures. (Author)

  2. Natural Gas Exploration in Sichuan Basin

    Institute of Scientific and Technical Information of China (English)

    Hu Guangcan

    1995-01-01

    @@ Sichuan Basin located in the eastern part of Sichuan province, is a structural basin with obvious boundaries . It is also a geographic basin and covers an area of about180×103 km2. The basin is surrounded by mountains with altitudes of 1000-3000m above sea level. The western part of the basin is the Chengdu Plain.The middle part of the basin is hills with altitudes of300-600m above sea level. The eastern part of the basin is featured by bar anticlinal hills with a northeast-southwest trend and are separated in the middle by open flatlands .The hills have an altitude of 700-800m above sea level.

  3. Brachytherapy boost and cancer-specific mortality in favorable high-risk versus other high-risk prostate cancer

    Science.gov (United States)

    Muralidhar, Vinayak; Xiang, Michael; Orio, Peter F.; Martin, Neil E.; Beard, Clair J.; Feng, Felix Y.; Hoffman, Karen E.

    2016-01-01

    Purpose Recent retrospective data suggest that brachytherapy (BT) boost may confer a cancer-specific survival benefit in radiation-managed high-risk prostate cancer. We sought to determine whether this survival benefit would extend to the recently defined favorable high-risk subgroup of prostate cancer patients (T1c, Gleason 4 + 4 = 8, PSA 20 ng/ml). Material and methods We identified 45,078 patients in the Surveillance, Epidemiology, and End Results database with cT1c-T3aN0M0 intermediate- to high-risk prostate cancer diagnosed 2004-2011 treated with external beam radiation therapy (EBRT) only or EBRT plus BT. We used multivariable competing risks regression to determine differences in the rate of prostate cancer-specific mortality (PCSM) after EBRT + BT or EBRT alone in patients with intermediate-risk, favorable high-risk, or other high-risk disease after adjusting for demographic and clinical factors. Results EBRT + BT was not associated with an improvement in 5-year PCSM compared to EBRT alone among patients with favorable high-risk disease (1.6% vs. 1.8%; adjusted hazard ratio [AHR]: 0.56; 95% confidence interval [CI]: 0.21-1.52, p = 0.258), and intermediate-risk disease (0.8% vs. 1.0%, AHR: 0.83, 95% CI: 0.59-1.16, p = 0.270). Others with high-risk disease had significantly lower 5-year PCSM when treated with EBRT + BT compared with EBRT alone (3.9% vs. 5.3%; AHR: 0.73; 95% CI: 0.55-0.95; p = 0.022). Conclusions Brachytherapy boost is associated with a decreased rate of PCSM in some men with high-risk prostate cancer but not among patients with favorable high-risk disease. Our results suggest that the recently-defined “favorable high-risk” category may be used to personalize therapy for men with high-risk disease. PMID:26985191

  4. Geodynamics of the Sivas Basin (Turkey): from a forearc basin to a retroarc foreland basin

    Science.gov (United States)

    Legeay, Etienne; Ringenbach, Jean-Claude; Kergaravat, Charlie; Callot, Jean-Paul; Mohn, Geoffroy; Kavak, Kaan

    2016-04-01

    Anatolia records the consumption of several oceanic basins, from the Northern Neotethys domain, by north-dipping subduction until the end of Mesozoic. The associated obduction event occurred during Campanian, from North to South and from Greece to Oman, leading to the emplacement of ophiolite thrust sheets and associated ophiolitic mélange. In particular, the Sivas Basin in Eastern Anatolia is located at the boundary between the Kırsehir block to the East, Pontide arc to the North and Tauride Platform to the South, sutured by ophiolitic belts. The Sivas Basin formed a Tertiary fold-and-thrust belt, which exhibits mainly north verging thrust in Paleogene deposits, and South verging thrust in oligo-miocene sequence. To understand the northern verging thrust above south verging obduction, it is necessary to zoom out of the basin, and include a set of processes that affect the eastern Anatolia. This study aims to characterize the structural and sedimentary evolution of the Sivas Basin, based on a fieldwork approach, coupled to the interpretation of subsurface data, thermochronology and biostratigraphy. The Sivas Basin was initiated in a forearc setting relatively to the subduction of the Inner-Tauride Ocean while the associated ophiolites are obducted onto the northern passive margin of the Tauride margin. Early Maastrichtian to Paleocene deposits are represented by carbonate platforms located on ophiolitic highs, passing to turbidites and olistostomes toward the North. The early Eocene sediments, mainly composed of ophiolitic clasts, are deposited on a regional unconformity marked along the southern margin of the basin by incisions in response to the emergence of north-verging thrust. The middle Eocene sediments, intensively folded by northward thrusting, are mostly represented by flysch type deposits (olistostromes, mass-flows and turbidites). The onset of the compression is related to the initiation of the Taurus shortening in a retroarc situation, in response to

  5. Successor Characteristics of the Mesozoic and Cenozoic Songliao Basins

    Institute of Scientific and Technical Information of China (English)

    LI Zhongquan; Timothy KUSKY; YING Danlin; GUO Xiaoyu; LI Hongkui

    2008-01-01

    The Songliao basin is a complex successor basin that was initiated in the Mesozoic and experienced multiple periods of reactivation. Based on seismic and drilling data, as well as regional geologic research, we suggest that the Songliao basin contains several different successor basins resting on top of Carboniferous-Permian folded strata forming the basement to the Songliao basin. These basins include the Triassic-Mid Jurassic Paleo-foreland basin, the Late Jurassic-Early Cretaceous downfaulted basin, and an early Cretaceous depressed basin (since the Denglouku Group). This paper presents a systematic study of the basin-mountain interactions, and reveals that there are different types of prototype basin at different geologic times. These prototype basins sequentially superimposed and formed the large Songliao basin. Discovery of the Triassic-early Middle Jurassic paleo-foreland basin fills a Triassic-early Middle Jurassic gap in the geologic history of the Songliao basin. The paleoforeland basin, downfaulted basin, and depressed thermal subsidence basin all together represent the whole Mesozoic-Cenozoic geologic history and deformation of the Songliao basin. Discovery of the Triassic-early Middle Jurassic paleo-foreland basin plays an important role both for deep natural gas exploration and the study of basin-mountain coupling in north China and eastern China in general. This example gives dramatic evidence that we should give much more attention to the polyphase tectonic evolution of related basins for the next phase of exploration and study.

  6. THE ADVANCED CHEMISTRY BASINS PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    William Goddard; Peter Meulbroek; Yongchun Tang; Lawrence Cathles III

    2004-04-05

    In the next decades, oil exploration by majors and independents will increasingly be in remote, inaccessible areas, or in areas where there has been extensive shallow exploration but deeper exploration potential may remain; areas where the collection of data is expensive, difficult, or even impossible, and where the most efficient use of existing data can drive the economics of the target. The ability to read hydrocarbon chemistry in terms of subsurface migration processes by relating it to the evolution of the basin and fluid migration is perhaps the single technological capability that could most improve our ability to explore effectively because it would allow us to use a vast store of existing or easily collected chemical data to determine the major migration pathways in a basin and to determine if there is deep exploration potential. To this end a the DOE funded a joint effort between California Institute of Technology, Cornell University, and GeoGroup Inc. to assemble a representative set of maturity and maturation kinetic models and develop an advanced basin model able to predict the chemistry of hydrocarbons in a basin from this input data. The four year project is now completed and has produced set of public domain maturity indicator and maturation kinetic data set, an oil chemistry and flash calculation tool operable under Excel, and a user friendly, graphically intuitive basin model that uses this data and flash tool, operates on a PC, and simulates hydrocarbon generation and migration and the chemical changes that can occur during migration (such as phase separation and gas washing). The DOE Advanced Chemistry Basin Model includes a number of new methods that represent advances over current technology. The model is built around the concept of handling arbitrarily detailed chemical composition of fluids in a robust finite-element 2-D grid. There are three themes on which the model focuses: chemical kinetic and equilibrium reaction parameters, chemical

  7. Experimental Drainage Basins in Israel

    Science.gov (United States)

    Laronne, J. B.; Lekach, J.; Cohen, H.; Gray, J.

    2002-12-01

    Within the hyper-arid to semiarid areas of Israel are three experimental drainage basins. They are the Nahal (stream in Hebrew) Yael, subdivided into five sub-basins, Rahaf-Qanna'im (main and tributary, respectively) and Eshtemoa. These basins vary in drainage area and climate, and in monitoring duration and type. All are drained by gravel-bed channels. As the size of monitored drainage area is limited, 3-4 additional representative basins covering areas of 300, 1000, 2000 and 8000 square kilometers will likely be implemented in the next decade. The basins have precipitation, runoff, sediment and fluviomorphological records. Each was conceived for differing purposes, but all share the common two objectives for the continuous monitoring: 1. Many hydrological issues may be approached if, and only if, there are prototype databases on a wide spectrum of hydrological processes; and 2. There is a need for long-term records to assess large floods and subsequent hydrologic and geomorphic recovery. Lessons derived from a large number of research projects on these experimental basins focus on characteristics of runoff in arid climates. For example, the effect of the spatial distribution of rainfall on runoff generation becomes increasingly important with aridity. Rainfall angle on hillslopes and storm intensity and direction derived from rainfall recorders and radar backscatter are crucial for explanation of runoff response. Runoff hydrographs tend to have more bores, shorter-duration peaks, briefer recessions, longer dry periods, and are more variable in terms of flood volume and peaks with increased aridity. Suspended-sediment fluxes, yields and concentrations are relatively large in the semiarid realm, reaching maxima at the beginning of a flood season and after long dry spells. Bedload fluxes are exceptionally high from dryland basins in which hillslopes are minimally vegetated and where bedload transport takes place in channels lacking an armor layer. Bedload

  8. Salt Lake in Chaidamu Basin

    Institute of Scientific and Technical Information of China (English)

    王良华

    2007-01-01

    Chaidamu Basin(柴达木盆地) is in the west of China. It covers an area(地区) of 220,000 square kilometres(平方公里). The number of salt lakes(盐湖) is more than twenty in it. Chaerhan(察尔汗) Salt Lake is the largest in this area. If you get here, you will find that in the lake there is no water but a thick layer(层) of salt. You can walk in it without difficulty, and cars can come and go across it. The thickest layer of salt in this basin is about fifty metres thick. People tried their best to use the salt to build house...

  9. Discussion on the exploration & development prospect of shale gas in the Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Dazhong Dong

    2015-01-01

    Full Text Available The Sichuan Basin, a hotspot and one of the most successful areas for shale gas exploration and development, can largely reflect and have a big say in the future prospect of shale gas in China. Through an overall review on the progress in shale gas exploration and development in the Sichuan Basin, we obtained the following findings: (1 the Sichuan Basin has experienced the marine and terrestrial depositional evolution, resulting in the deposition of three types of organic-matter-rich shales (i.e. marine, transitional, and terrestrial, and the occurrence of six sets of favorable shale gas enrichment strata (i.e. the Sinian Doushantuo Fm, the Cambrian Qiongzhusi Fm, the Ordovician Wufeng–Silurian Longmaxi Fm, the Permian Longtan Fm, the Triassic Xujiahe Fm, and the Jurassic Zhiliujing Fm; (2 the five key elements for shale gas accumulation in the Wufeng-Longmaxi Fm are deep-water shelf facies, greater thickness of organic-rich shales, moderate thermal evolution, abundant structural fractures, reservoir overpressure; and (3 the exploration and development of shale gas in this basin still confronts two major challenges, namely, uncertain sweet spots and potential prospect of shale gas, and the immature technologies in the development of shale gas resources at a depth of more than 3500 m. In conclusion, shale gas has been discovered in the Jurassic, Triassic and Cambrian, and preliminary industrial-scale gas has been produced in the Ordovician-Silurian Fm in the Sichuan Basin, indicating a promising prospect there; commercial shale gas can be produced there with an estimated annual gas output of 30–60 billion m3; and shale gas exploration and production experiences in this basin will provide valuable theoretical and technical support for commercial shale gas development in China.

  10. Cuddapah basin and its environs as first-order uranium target in the Proterozoics of India

    International Nuclear Information System (INIS)

    In peninsular India the middle Proterozoic intracratonic Cuddapah basin and its environs possess good geological favorability for several types of uranium deposits. Investigations so far have revealed the strata bound carbonate-hosted uranium mineralization in the Vempalle dolomitic limestone (e.g. Tummallapalle) and in the Pulivendla quartzite, confined to the lower part of the Cuddapah supergroup, and the structurally controlled uranium mineralization in the late Archaean/early Proterozoic granitoids and metamorphics along eastern (e.g. Kasturigattu), south-western (e.g. Sanipaya and T-Sanipaya and T-Sundapalle), and northern margins (e.g. Lambapur-Yellapur) of the Cuddapah basin. Based on the present level of work within the Cuddapah Basin and its environs, the following favourable locales and prospecting techniques have been suggested to identify the unconformity/vein-type high grade uranium deposits. (i) Detailed geological examination of the contact of basement with mid-Proterozoic Gulcheru/Nagari quartzite for locating unconformity-type uranium mineralisation. (ii) Extensive ground radiometric survey along the unconformity between basement granite and outliers of Srisailam formation, Banganpalle formation, Cumbum/Pullampet formation and Bairenkonda formation along northern and eastern margins of Cuddapah basin. (iii) Examination of the contact zone of the igneous intrusives (syenite and granite) into the Cumbum formation of central and northeastern parts of the basin e.g. Chelima - Giddalur area. (iv) Geophysical survey like resistivity (viz. SP, IP, TEM) to (a) delineate the concealed sulphide-rich zones along the prominent structures of the basinal margins and (b) study the possible existence under cover of quartzite and their subsurface behaviour for the fracture zones identified in the T. Sundapalle-Sanipaya, Pincha, Maddireddigaripalle, Chakrayapeta and Vepamanipeta areas. (author). 22 refs., 1 fig., 3 tabs

  11. Characteristics of helium isotopes in natural gas and its tectonic implication in Bohai Bay Basin

    Institute of Scientific and Technical Information of China (English)

    DING Weiwei; DAI Jinxin; YANG Shufeng; CHEN Hanlin

    2006-01-01

    Analysis on helium isotopes in natural gas in Bohai Bay Basin showed their mantle-origin indicated by high 3He/4He ratio. The span of 3He/4He ratio increased from west to east. This pattern implied a close relationship to the local tectonic setting. Bohai Bay Basin experienced intensive neo-tectonic activities in the Cenozoic. Widespread faulted-depressions and strong volcanic eruptions manifested its extensional tectonics. Abiogenic natural gas could be released from magmas and migrate upward through deep faults during the extension. Tectonic conditions in the area would favor upward invasion and reservation of mantle-originated helium. Furthermore, with decrease of convergence rate between the Pacific and the Eurasia Plate, the subduction slab of the Pacific Plate rolled back and became steeper, resulting in mantle flow and other tectonic activities migrating from west to east in nature, and caused the variation in isotopic helium ratios.

  12. Preliminary study of the uranium potential of the Triassic Sanford basin and Colon cross structure, North Carolina

    International Nuclear Information System (INIS)

    A preliminary geologic investigation was conducted to determine if Triassic sedimentary rocks of the Sanford basin and Colon cross structure in North Carolina are favorable hosts for uranium deposits. Rocks of adjacent Carolina slate belt were also examined as a potential source of uranium. On the basis of favorability criteria for sandstone-type uranium deposits, and geologic and geophysical investigations of the study area, the most favorable sites for further investigation are (1) at the contacts between the Pekin and Cumnock and between the Pekin and Sanford Formations near the Colon cross structure and (2) at the base of the Jonesboro fault, which lies below the Sanford Formation, northwest of Sanford. The highly weathered granites southeast of the Jonesboro fault were a source of the detritus deposited on the cross structure and may have been a primary source of uranium. Uranium leached from the coarse sediment (Pekin Formation) of the cross structure may have been transported downdip and may have been precipitated by the carbonaceous shales of the Cumnock Formation on the western side of the cross structure or at the Pekin-Sanford contact to the east. The Jonesboro fault may provide an impermeable barrier to ground-water migration in the metamorphosed basement rocks below the Triassic sediments. Such a barrier would constitute a favorable site for the precipitation and retention of uranium. Scintillometer surveys and laboratory analyses indicate no anomalous surface radioactivity in the study area. However, deep surface weathering may have caused the uranium to be leached from the exposed rocks and redeposited at depth. Geologic investigations show that conditions which have proven favorable for deposition of uranium in other areas are present in the Triassic rocks of the Sanford basin and Colon cross structure. However, because of deep surface weathering, further subsurface studies are necessary to confirm the favorability of the rocks as hosts for uranium

  13. Petroleum geology of the northwest basin, Argentina

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Jae Hong [Yonsei University, Seoul (Korea, Republic of); Oh, Jae Ho [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of); Kim, Jong Young [Dong Won Co., Sabuk (Korea, Republic of)

    1997-06-30

    Petroleum geology of the Northwest Basin, Argentina has been studied in detail using seismic reflection profiles, drill holes and structure maps. The Northwest Basin comprises the following four successor basins that are different in characteristics and tectonic development: pre-Carboniferous, Carboniferous, Cretaceous, and Tertiary basins. Petroleum plays in the Northwest Basin can be divided into four types based on hydrocarbon-trap structures. These include thrust-folds, paleo-channels, volcanic mounds and roll-over anticlines related to normal faulting. The thrust-fold structure is a typical trap structure of pre-Carboniferous and Carboniferous basins, and consists of Cretaceous sedimentary rocks in southern exploration areas of the Northwest Basin. Paleo-channels provide a new possibility to the Carboniferous basin, and several of them occur in northern exploration areas of the Northwest Basin. Volcanic mounds and roll-over anticlines associated with the normal fault are related to the rifting event and play an important role in the Cretaceous basin. New prospects will be found if the above play types are well utilized. (author). 12 refs., 15 figs.

  14. The role of p53 in radiation therapy outcomes for favorable-to-intermediate-risk prostate cancer

    International Nuclear Information System (INIS)

    Purpose: Some prostate cancers may have molecular alterations that render them less responsive to radiation therapy; identification of these alterations before treatment might allow improved treatment optimization. This study investigated whether p53, a potential molecular determinant, could predict long-term radiation therapy outcome in a restricted group of relatively favorable-risk prostate cancer patients treated uniformly with irradiation alone. Methods and Materials: This study included 53 patients previously treated with radiotherapy for favorable-to-intermediate-risk prostate cancer. These patients were selected for relatively low pretreatment PSAs (≤21 ng/mL) and Gleason scores (≤7) to decrease the likelihood of nonlocalized disease, because disease localization was necessary to examine the efficacy of localized radiation therapy. The status of p53 was immunohistochemically assessed in paraffin-embedded pretreatment biopsy specimens, along with appropriate controls. This marker was selected based upon a usable mutation prevalence in early-stage prostate cancer and its potential linkage with radiation response via cell cycle, DNA repair, and cell death pathways. Correlation between p53 mutation and clinical outcome was analyzed in univariate and multivariate fashion and included conventional prognosticators, such as stage, grade, and PSA. Freedom from biochemical failure was determined using American Society for Therapeutic Radiology and Oncology criteria. Limitations of prior studies were potentially avoided by requiring adequate posttreatment follow-up (median follow-up in nonfailing patients of 5.1 years), as well as pretreatment PSA and Gleason scores that suggested localized disease, and uniformity of treatment. Results: The total group of 53 favorable-to-intermediate-risk patients demonstrated an actuarial biochemical failure rate of 35% at 5 years. Forty percent of all specimens had a greater than 10% labeling index for p53 mutation, and

  15. Natural Gas Resource in Jurassic, Y Faulted Subbasin of Songliao Basin

    Institute of Scientific and Technical Information of China (English)

    Yang Haibo; Hu Yutao; Wei Xinghua

    2000-01-01

    Y faulted depression is located in the southeast of Songliao basin, which is another important area explored for natural gas in deep Formation after Xujiaweizi. But it is lowly explored and is not likely to make a major breakthrough in nature gas exploration for shallow and medium layers. The data on the geochemistry and geology indicate that the deep source rocks, especially the Jurassic mudstone bas great potentials of natural gas generation. Based on this, the paper examines the conditions of natural gas generation and further points out the favorable prospective gas - bearing area. The results show that the amount of natural gas generated from the Jurassic mudstone in the Y faulted depression is 8.42 × 1012m3 and the favorable gas - generating area is the body of the faulted depression.

  16. Geodynamic evolution of sedimentary basins

    Energy Technology Data Exchange (ETDEWEB)

    Roure, F.; Ellouz, N.; Shein, V.S.; Skvortsov, I.I. [eds.

    1996-12-01

    This volume constitutes the proceedings of a conference held in Moscow in 1992, and organized by the Institut Francais du Petrole (IFP), the IGIRGI and VNIGNI Russian institutes under the auspices of the Russian Ministries of Fuels and Energy, Ecology and Nature. Geological features of the CIS countries, especially Russia, have driven their geologists` interest to specific questions as the petroleum potential of Proterozoic series, the resources located at a depth of 5000 m and more, or the impact of recent deformations on petroleum exploration and production. From the 27 papers of this conference, only 16 were selected which deal with oil and natural gas fields or coal deposits and geologic traps in the extensional and compressional basins of the CIS republics or in their western counterparts, or with physical and numerical structural models and other modeling techniques used for petroleum potential appraisal in sedimentary basins. The other papers deal with thematic aspects of basin formation in general or in specific areas with no reference to hydrocarbon genesis. (J.S.).

  17. Basin stability in delayed dynamics

    Science.gov (United States)

    Leng, Siyang; Lin, Wei; Kurths, Jürgen

    2016-02-01

    Basin stability (BS) is a universal concept for complex systems studies, which focuses on the volume of the basin of attraction instead of the traditional linearization-based approach. It has a lot of applications in real-world systems especially in dynamical systems with a phenomenon of multi-stability, which is even more ubiquitous in delayed dynamics such as the firing neurons, the climatological processes, and the power grids. Due to the infinite dimensional property of the space for the initial values, how to properly define the basin’s volume for delayed dynamics remains a fundamental problem. We propose here a technique which projects the infinite dimensional initial state space to a finite-dimensional Euclidean space by expanding the initial function along with different orthogonal or nonorthogonal basis. A generalized concept of basin’s volume in delayed dynamics and a highly practicable calculating algorithm with a cross-validation procedure are provided to numerically estimate the basin of attraction in delayed dynamics. We show potential applicabilities of this approach by applying it to study several representative systems of biological or/and physical significance, including the delayed Hopfield neuronal model with multistability and delayed complex networks with synchronization dynamics.

  18. K West Basin canister survey

    International Nuclear Information System (INIS)

    A survey was conducted of the K West Basin to determine the distribution of canister types that contain the irradiated N Reactor fuel. An underwater camera was used to conduct the survey during June 1998, and the results were recorded on videotape. A full row-by-row survey of the entire basin was performed, with the distinction between aluminum and stainless steel Mark 1 canisters made by the presence or absence of steel rings on the canister trunions (aluminum canisters have the steel rings). The results of the survey are presented in tables and figures. Grid maps of the three bays show the canister lid ID number and the canister type in each location that contained fuel. The following abbreviations are used in the grid maps for canister type designation: IA = Mark 1 aluminum, IS = Mark 1 stainless steel, and 2 = Mark 2 stainless steel. An overall summary of the canister distribution survey is presented in Table 1. The total number of canisters found to contain fuel was 3842, with 20% being Mark 1 Al, 25% being Mark 1 SS, and 55% being Mark 2 SS. The aluminum canisters were predominantly located in the East and West bays of the basin

  19. Gender related differences in response to "in favor of myself" wellness program to enhance positive self & body image among adolescents.

    Directory of Open Access Journals (Sweden)

    Moria Golan

    Full Text Available BACKGROUND: Physical, neurological and psychological changes are often experienced differently by male and female adolescents. Positive self-esteem, emotional well-being, school achievements, and family connectedness are considered as protective factors against health-compromising behaviors. This study examines the gender differences in respect to the effect of a school-based interactive wellness program--"In Favor of Myself"--on self-image, body image, eating attitudes and behaviors of young adolescents. METHODS: Two hundred and ten adolescents (mean age 13.5 participated in the intervention group, 55% were girls and 45% boys. Program consisted of eight 90-minutes structured sessions integrated into a regular school coping skills curriculum. The program focused on self-esteem, self-image, body image, media literacy and cognitive dissonance. The overall impact of the program and the study protocol were previously published. RESULTS: Overall, there are gender related differences in respect to body image and self-image in young adolescents in response to "In Favor of Myself". Compared to boys, girls reported at baseline higher self-esteem, being more contingent by appearance, and their self-image was more influenced by popularity, appearance, interpersonal communication and admired people. Furthermore girls presented greater gap between current body figure and perceived ideal figure. Not only were girls more dissatisfied with their body, but they were more active in attempts to become and/or remain "thin". At program termination, gender × time effect was detected in reduction of self-worth contingent by others, change in importance given to achievements at schools, parents' perceptions, as well as the impact of comparisons to friends and family members on self-image. CONCLUSIONS: Girls exhibited more gains than boys from 'In Favor of Myself' which raise the questions about how effective would be the program when delivered in mixed gender groups

  20. The effect of "in favor of myself": preventive program to enhance positive self and body image among adolescents.

    Directory of Open Access Journals (Sweden)

    Moria Golan

    Full Text Available BACKGROUND: Positive self-esteem, emotional well-being, school achievements and family connectedness are considered protective factors against health-compromising behaviors. This study examined the effect of an interactive, community-based, media literacy and dissonance wellness program, In Favor of Myself, on the self-image, body image, eating attitudes and behavior of young adolescents. A preliminary cohort study was conducted among 972 program participants who did not take part in the controlled trial. Over 75% of participants said they would recommend the program to their friends. METHODS: A controlled trial was conducted to evaluate program acceptability, efficacy and effectiveness among 259 participants (210 in the intervention group and 49 in the control group, aged 12-14 years, who completed questionnaires during at least two assessment times. Program materials were provided, along with leaders' training, in order to ensure quality program delivery and creation of a wide network of committed program leaders. RESULTS: The program significantly reduced drive for thinness and self-worth contingent upon others' approval, the gap between current body figure and ideal figure, and the impact of mood on girls' self-image. Superiority was found among those participating in the intervention group with respect to recognizing media strategies, the influence of media on desire to change, and the influence of appearance on self-confidence and drive for thinness. CONCLUSIONS: In Favor of Myself shows promising results for strengthening adolescents' ability to cope with the challenges of their life stage. Suggestions for improving In Favor of Myself are presented.

  1. L'adoption par les agriculteurs de pratiques agricoles favorables à l'environnement : identification des facteurs de blocage

    OpenAIRE

    Aline Cattan; Laurent Mermet

    1992-01-01

    [fre] Par quels canaux et en quels termes des pratiques agricoles favorables à l'environnement (PAFE) sont-elles effectivement proposées aux agriculteurs ? Quels sont les facteurs qui tendent à bloquer, ou au contraire, à favoriser leur adoption par ces derniers ? Cet article présente les premiers constats d'une étude en cours sur ce sujet. Celle-ci repose sur une « double écoute », à la fois agro-économique et psycho-sociologique. La première étude de cas, en Côte-d'Or, a mis en évidence un ...

  2. Estado neoliberal y acumulación por desposesión a favor del capital glocal financiero

    OpenAIRE

    Marco Antonio Merchand Rojas

    2012-01-01

    El objetivo general de este trabajo es analizar por qué la acumulación por desposesión es una de lasmodalidades que se implementan indiscriminadamente en todos los órdenes de la economía mundial y representa la mejor forma para estabilizar el sistema capitalista a favor del capital financiero y en contra de la fuerza de trabajo. Las condiciones en que el capital se impone en cada espacio económico difieren en sus métodos y maneras de reproducirse; no obstante su carácter intrínseco de enajena...

  3. Syria after the Russian intervention: Moscow tips the military balance in favor of the regime, pursues parallel diplomacy

    OpenAIRE

    Oweis, Khaled Yacoub

    2016-01-01

    Russian airstrikes turned the tide of the conflict in favor of the regime of Bashar al Assad. Moscow announced a reduction in its military presence in Syria in March 2016 but has maintained its infrastructure in the country while continuing to build up Assad’s forces. The cessation of hostilities achieved through a deal between the United States and Russia has lessened the number of attacks against civilians and curbed fighting, but rebel areas remain under siege. At the same time, Russia has...

  4. Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors | Office of Cancer Genomics

    Science.gov (United States)

    We report the most common single-nucleotide substitution/deletion mutations in favorable histology Wilms tumors (FHWTs) to occur within SIX1/2 (7% of 534 tumors) and microRNA processing genes (miRNAPGs) DGCR8 and DROSHA (15% of 534 tumors). Comprehensive analysis of 77 FHWTs indicates that tumors with SIX1/2 and/or miRNAPG mutations show a pre-induction metanephric mesenchyme gene expression pattern and are significantly associated with both perilobar nephrogenic rests and 11p15 imprinting aberrations.

  5. Shrinking societies favor procreation.

    Science.gov (United States)

    Kent, M M

    1999-12-01

    Low birth rates and unprecedented improvements in life expectancy had brought a shrinking society to a rapidly expanding retirement-age population. In 1999, people aged 65 and older make up 15% or more of the populations in 19 countries. Furthermore, 14 country populations are already experiencing natural decrease, and a lot more will start to decline early in the 21st century. Due to this predicament, concerned countries have created policies that may encourage more childbearing by easing the opportunity costs of raising children. Among the policies are: 1) paid maternity and paternity leaves until a child is 2-3 years; 2) free child care; 3) tax breaks for large families; 4) family housing allowance; 5) cash paid to parents for raising a child. Governments of the shrinking societies believed that these policies could influence fertility because it affects the socioeconomic setting in which childbearing decisions are made. This paper also discusses Hungary, Japan, and Sweden fertility policies. PMID:12295635

  6. Favorable Financial Turf

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Tianjin's Binhai New Area lures the financial industry with preferential treatment If you were thinking about doing financial business in Shanghai, Hong Kong or Beijing, think again. Early in June this year, the State Council approved the establishment of a financial experimental zone for Tianjin's Binhai New Area, which will get preferential treatment that other cities can hardly expect to attain. While for a time the area's administration had to actively court financial institu-

  7. Em favor da talassografia

    Directory of Open Access Journals (Sweden)

    Jean-Louis Boudou

    2001-01-01

    Full Text Available A Talassografia (“descrição do mar” interessa-sepelos impactos físicos, biológicos, ecológicos... culturais da violenta antropização dos ambientes costeiros (oceânicos e continentais, caracterizados pelaexigüidade, vulnerabilidade, fragilidade e plasticidade. Como o Brasil é um “país marítimo”, os geó-grafos (os talassógrafos brasileiros são convidadosa intensificar suas pesquisas nas áreas costeiras e acriar novas estruturas para divulgá-las: Revista, Encontros, Associação, Pós-Graduação... tudo em prolda talassografia.

  8. A Favor del Plagio

    Directory of Open Access Journals (Sweden)

    Manuel Arranz

    2007-11-01

    Full Text Available Yo no tengo nada contra el plagio. Ustedes, como lectores, seguramente tampoco. Bueno, tal vez prejuicios. Es lógico que los tengan con tanto artículo condenándolo. Hasta ahora, que yo sepa, nadie ha escrito para defenderlo. Los que sí tienen algo, parece ser, son los autores. Una minoría al fin y al cabo. Ya sé que hay que respetar el derecho de las minorías, pero el asunto del plagio, como tantos otros, deberíamos examinarlo con más detalle, y preguntarnos, por ejemplo, ¿por qué se molestan tanto los autores cuando les plagian? ¿En nombre de qué?, sería también una buena pregunta. No me irán a decir a estas alturas que en nombre de la comunidad científica. A fin de cuentas el plagio beneficia la difusión de la ciencia. Los autores se molestan en nombre propio. Naturalmente tienen su derecho, no se lo vamos a discutir, pero, ¿no demuestra eso cierto narcisismo impropio de un científico? ¿La ciencia no es de todos?, como suelen decir en otras ocasiones.

  9. A Favor del Plagio

    OpenAIRE

    Manuel Arranz

    2007-01-01

    Yo no tengo nada contra el plagio. Ustedes, como lectores, seguramente tampoco. Bueno, tal vez prejuicios. Es lógico que los tengan con tanto artículo condenándolo. Hasta ahora, que yo sepa, nadie ha escrito para defenderlo. Los que sí tienen algo, parece ser, son los autores. Una minoría al fin y al cabo. Ya sé que hay que respetar el derecho de las minorías, pero el asunto del plagio, como tantos otros, deberíamos examinarlo con más detalle, y preguntarnos, por ejemplo, ¿por qué se molestan...

  10. Heat flow, deep formation temperature and thermal structure of the Tarim Basin, northwest China

    Science.gov (United States)

    Liu, Shaowen; Lei, Xiao; Feng, Changge; Li, Xianglan

    2016-04-01

    depth are the favorable conditions for hydrocarbon generation and preservation. As far as heat budget of the Tarim Basin is concerned, the radiogenic heat from the sedimentary cover accounts only for 20 percent of the surface heat flow (~9 mW/m2), while the mantle heat flow is estimated to be low as 6~15 mW/m2; this indicates the dominant contribution of crustal radiogenic heat to the observed heat flow. Any variations in surface heat flow for the Tarim Basin can be due only to changes in crustal heat production. Thermal contrast between the Tarim Basin and Tibet Plateau, represented by a difference in surface heat flow and deep crustal temperature, is remarkable. This inherited thermal contrast can be traced as far as before the India-Asia collision. Moreover, the lithosphere beneath the Tarim Basin is sufficiently strong to resist the gravitational potential energy difference and tectonic forces from Tibet. The observed thermal and rheological contrast accounts for the differential Cenozoic deformation in the Tarim Basin and adjacent areas.

  11. The geologic history of Margaritifer basin, Mars

    Science.gov (United States)

    Salvatore, M. R.; Kraft, M. D.; Edwards, C. S.; Christensen, P. R.

    2016-03-01

    In this study, we investigate the fluvial, sedimentary, and volcanic history of Margaritifer basin and the Uzboi-Ladon-Morava outflow channel system. This network of valleys and basins spans more than 8000 km in length, linking the fluvially dissected southern highlands and Argyre basin with the northern lowlands via Ares Vallis. Compositionally, thermophysically, and morphologically distinct geologic units are identified and are used to place critical relative stratigraphic constraints on the timing of geologic processes in Margaritifer basin. Our analyses show that fluvial activity was separated in time by significant episodes of geologic activity, including the widespread volcanic resurfacing of Margaritifer basin and the formation of chaos terrain. The most recent fluvial activity within Margaritifer basin appears to terminate at a region of chaos terrain, suggesting possible communication between surface and subsurface water reservoirs. We conclude with a discussion of the implications of these observations on our current knowledge of Martian hydrologic evolution in this important region.

  12. Enfrentamento de situações adversas e favoráveis por pessoas idosas em condições crônicas de saúde Enfrentamiento de situaciones adversas y favorables por ancianos en condiciones de salud crónicas Coping with the adverse and favorable situations by aged persons in chronic health conditions

    Directory of Open Access Journals (Sweden)

    Mercedes Trentini

    2005-02-01

    Full Text Available Investigar as situações adversas e favoráveis vivenciadas por pessoas idosas em condições crônicas de saúde, e as estratégias de enfrentamento, foi o objetivo deste estudo. A amostra constou de 18 idosos e as informações foram obtidas por entrevistas com questões abertas. Para a análise, utilizou-se a técnica do Discurso do Sujeito Coletivo. Os resultados mostraram que a morte e a separação de familiares foram vistas como as mais significantes situações adversas. As situações favoráveis incluíram a família, sabedoria, experiência, aposentadoria e a vida em si. O enfrentamento se apresentou focalizado no problema e na emoção. O enfrentamento focalizado na emoção se caracterizou pelo sentimento de fé, pelo trabalho, pela busca de ajuda da família e de outras pessoas significantes, pela participação em grupo de idosos e pela rejeição às perdas naturais relacionadas ao envelhecimento. O enfrentamento, focalizado no problema, foi representado pela busca do atendimento médico e cuidado do corpo, numa tentativa de minimizar os problemas.Propósito: investigar las situaciones adversas y favorables vividas por personas mayores en condiciones de salud crónicas, además de averiguar las estrategias de enfrentamiento. Método: la muestra fue compuesta por 18 ancianos. Las informaciones fueron obtenidas mediante entrevistas con cuestiones abiertas. Para el análisis se utilizó la técnica del Discurso del Sujeto Colectivo. Resultados: los hallazgos mostraron que la muerte y la separación de familiares se presentaron como las situaciones adversas las más significativas. Las situaciones favorables incluyeron la familia, sabiduría, experiencia, jubilación y la vida en si. El "coping" fue enfocado en el problema y en la emoción. El enfrentamiento focalizado en la emoción se caracterizó por el sentimiento de fe, por el trabajo, por la búsqueda de ayuda de la familia y de otras personas significativas, por el vínculo a

  13. Drainage basin delineations for selected USGS streamflow-gaging stations in Virginia (Drainage_Basin)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Drainage_Basin polygon feature class was created as a digital representation of drainage basins for more than 1,650 continuous-record streamflow-gaging...

  14. Inter-basin dynamics on multidimensional potential surfaces. I. Escape rates on complex basin surfaces

    Science.gov (United States)

    Despa, Florin; Berry, R. Stephen

    2001-11-01

    In this report, we present a general prescription for computing the escape rate of the system from a basin with full consideration of the topographical fingerprint of that basin. The method is based on a solution of the reduced Fokker-Planck equation and built up to allow the separation of the inter-basin dynamics from that of the intra-basin motion. The main result is that when local well populations thermalize within a basin, local minima, especially those of higher energy, enhance the escape rate from the basin. Also, numerical analyses lead to the inference that kinetic traps of "wrong" structures are distinctive topographical patterns which may produce kinetic properties similar to those of the primary basin, i.e., that containing the global minimum, but lie in other basins.

  15. Floral reward presentation favored the expression of male function in the pollen-only flower Melastoma malabathricum

    Institute of Scientific and Technical Information of China (English)

    Zhong-Lai LUO; Shi CHEN; Dian-Xiang ZHANG

    2012-01-01

    Animal-pollinated plant species modulate the presentation of pollinator rewards to maximize reproductive success.In plants providing pollen as the only reward for pollinators,it is usually difficult to unravel the dual roles of reward presentation and the realization of male and female functions (pollen removal and deposition).Exploiting the two types of anther in the androecia of Melastoma malabathricum L.,we examined whether the removal of pollen for reward is regulated primarily to favor male function or female function.Pollen removal by carpenter bees from the feeding and pollination anthers,as well as pollen deposition on the stigmas,were quantified during anthesis of M.malabathricum.There was no significant difference in pollen removal rates from the feeding and pollination anthers of M.malabathricum between the onset of anthesis and flower wilting.The stigmatic pollen loads exceeded the ovule number after three sonication bouts,and female function was satisfied earlier than male function.The results support the hypothesis that the presentation of pollination reward in this species is regulated primarily to favor the expression of male function,rather than female function,in agreement with the pollen-donation hypothesis.A cooperative relationship between the feeding and pollination anthers was demonstrated in heterantherous flowers,which optimizes the balance in investments between pollinator rewards and "functional pollen" for gene transfer.

  16. Coexpression of SFRP1 and WIF1 as a prognostic predictor of favorable outcomes in patients with colorectal carcinoma.

    Science.gov (United States)

    Huang, Shiyong; Zhong, XiaoMing; Gao, Jun; Song, Rongfeng; Wu, Hongyu; Zi, Shuming; Yang, Shijie; Du, Peng; Cui, Long; Yang, Chun; Li, Zikang

    2014-01-01

    Colorectal tumorigenesis is ascribed to the activity of Wnt signaling pathway in a ligand-independent manner mainly through APC and CTNNB1 gene mutations and in a ligand-dependent manner through low expression of Wnt inhibitors such as WNT inhibitory factor 1 (WIF1) and secreted frizzled related protein 1 (SFRP1). In this study we found that WIF1 protein expression was increased and SFRP1 was decreased significantly in CRC tissue versus normal tissue, and high expression of WIF1 was associated with big tumor diameters and deep invasion, and loss of SFRP1 expression was associated with the left lesion site, deep invasion, and high TNM stage. Among the four expression patterns (WIF+/SFRP1+, WIF+/SFRP1-, WIF-/SFRP1+, and WIF-/SFRP1-) only coexpression of WIF1 and SFRP1 (WIF+/SFRP1+) was associated with favorable overall survival, together with low TNM stage, as an independent prognostic factor as shown in a multivariate survival model. The results indicated that WIF1 seemed to play an oncogenic role, while SFRP1 seemed to play an oncosuppressive role although both of them are secreted Wnt antagonists. Coexpression of SFRP1 and WIF1, rather than SFRP1 or WIF1 alone, could be used, together with low TNM stage, as a prognostic predictor of favorable outcomes in CRC. PMID:24949429

  17. Coexpression of SFRP1 and WIF1 as a Prognostic Predictor of Favorable Outcomes in Patients with Colorectal Carcinoma

    Directory of Open Access Journals (Sweden)

    Shiyong Huang

    2014-01-01

    Full Text Available Colorectal tumorigenesis is ascribed to the activity of Wnt signaling pathway in a ligand-independent manner mainly through APC and CTNNB1 gene mutations and in a ligand-dependent manner through low expression of Wnt inhibitors such as WNT inhibitory factor 1 (WIF1 and secreted frizzled related protein 1 (SFRP1. In this study we found that WIF1 protein expression was increased and SFRP1 was decreased significantly in CRC tissue versus normal tissue, and high expression of WIF1 was associated with big tumor diameters and deep invasion, and loss of SFRP1 expression was associated with the left lesion site, deep invasion, and high TNM stage. Among the four expression patterns (WIF+/SFRP1+, WIF+/SFRP1−, WIF−/SFRP1+, and WIF−/SFRP1− only coexpression of WIF1 and SFRP1 (WIF+/SFRP1+ was associated with favorable overall survival, together with low TNM stage, as an independent prognostic factor as shown in a multivariate survival model. The results indicated that WIF1 seemed to play an oncogenic role, while SFRP1 seemed to play an oncosuppressive role although both of them are secreted Wnt antagonists. Coexpression of SFRP1 and WIF1, rather than SFRP1 or WIF1 alone, could be used, together with low TNM stage, as a prognostic predictor of favorable outcomes in CRC.

  18. X-rays radiation directly produced favorable and harmful effects on the constituents of different medicinal plants

    Directory of Open Access Journals (Sweden)

    S M Al-Nimer Marwan

    2009-01-01

    Full Text Available The effect of ionizing radiation on the constituents of solid materials of medicinal plants was studied in few reports. The present study was performed to investigate the direct effect of 1.9Gy/min X-rays radiation on the dry leaves of Camellia sinensis (green tea, Salvia officinalis (sage, barks of Cinnamomum verum (cinnamon and tuberous of Zingiber officinale Rosc. (ginger. Three extracts (1% were prepared for each medicinal plant; aqueous, ethanol and methanol. The UV-Visible spectra, and biochemical constituents of each non irradiated and irradiated extract were determined. The results showed that X-rays radiation induced remarkable changes in UV-Visible spectra of irradiated compared with non irradiated medicinal plants. This effect was well observed with irradiated green tea leaves. Irradiated medicinal plants lost considerable percents of allantoin and higher percents of flavonoids as well as total polyphenols were lost from irradiated ginger and cinnamon. Irradiated medicinal plants were superior than non irradiated in releasing nitric oxide. It concludes that irradiated medicinal plants carried favorable and harmful effects on their constituents and their favorable effects can be clinically as well as experimentally applied.

  19. A cancer-favoring oncolytic vaccinia virus shows enhanced suppression of stem-cell like colon cancer

    Science.gov (United States)

    Yoo, So Young; Bang, Seo Young; Jeong, Su-Nam; Kang, Dae Hwan; Heo, Jeong

    2016-01-01

    Stem cell-like colon cancer cells (SCCs) pose a major challenge in colon cancer treatment because of their resistance to chemotherapy and radiotherapy. Oncolytic virus-based therapy has shown promising results in uncured cancer patients; however, its effects on SCCs are not well studied yet. Here, we engineered a cancer-favoring oncolytic vaccinia virus (CVV) as a potent biotherapeutic and investigated its therapeutic efficacy in terms of killing SCCs. CVV is an evolved Wyeth strain vaccinia virus (EVV) lacking the viral thymidine kinase. SCC models were established using human or mouse colon cancer spheres, which continuously expressed stemness markers. The cancer-favoring characteristics and different cytotoxic pathways for killing cancer cells successfully overrode general drug resistance, thereby killing colon cancer cells regardless of the presence of SCCs. Subcutaneously injected HT29 spheres showed lower growth in CVV-treated models than in 5-Fu-treated models. Intraperitoneally injected CT26 spheres induced tumor masses in the abdominal region. CVV-treated groups showed higher survival rates and smaller tumor mass formation, compared to 5-Fu-treated groups. Interestingly, the combined treatment of CVV with 5-Fu showed improved survival rates and complete suppression of tumor mass. The CVV developed in this study, thus, effectively suppresses SCCs, which can be synergistically enhanced by simultaneous treatment with the anticancer drug 5-Fu. Our novel CVV is highly advantageous as a next-generation therapeutic for treating colon cancer. PMID:26918725

  20. Coexpression of SFRP1 and WIF1 as a Prognostic Predictor of Favorable Outcomes in Patients with Colorectal Carcinoma

    Science.gov (United States)

    Huang, Shiyong; Zhong, XiaoMing; Gao, Jun; Song, Rongfeng; Wu, Hongyu; Zi, Shuming; Yang, Shijie; Du, Peng; Cui, Long; Yang, Chun; Li, Zikang

    2014-01-01

    Colorectal tumorigenesis is ascribed to the activity of Wnt signaling pathway in a ligand-independent manner mainly through APC and CTNNB1 gene mutations and in a ligand-dependent manner through low expression of Wnt inhibitors such as WNT inhibitory factor 1 (WIF1) and secreted frizzled related protein 1 (SFRP1). In this study we found that WIF1 protein expression was increased and SFRP1 was decreased significantly in CRC tissue versus normal tissue, and high expression of WIF1 was associated with big tumor diameters and deep invasion, and loss of SFRP1 expression was associated with the left lesion site, deep invasion, and high TNM stage. Among the four expression patterns (WIF+/SFRP1+, WIF+/SFRP1−, WIF−/SFRP1+, and WIF−/SFRP1−) only coexpression of WIF1 and SFRP1 (WIF+/SFRP1+) was associated with favorable overall survival, together with low TNM stage, as an independent prognostic factor as shown in a multivariate survival model. The results indicated that WIF1 seemed to play an oncogenic role, while SFRP1 seemed to play an oncosuppressive role although both of them are secreted Wnt antagonists. Coexpression of SFRP1 and WIF1, rather than SFRP1 or WIF1 alone, could be used, together with low TNM stage, as a prognostic predictor of favorable outcomes in CRC. PMID:24949429

  1. Pull-apart basin tectonic model is structurally impossible for Kashmir basin, NW Himalaya

    OpenAIRE

    Shah , A.A.

    2016-01-01

    Kashmir Basin in NW Himalaya is considered a Neogene-Quatermary piggyback basin that was formed as result of the continent-continent collision of Indian and Eurasian plates. This model however is recently challenged by a pull-apart basin model, which argues that a major dextral strike-slip fault through Kashmir basin is responsible for its formation. And here it is demonstrated that the new tectonic model is structurally problematic, and co...

  2. Hydrocarbon Migration and Accumulation in Dongying Basin

    Institute of Scientific and Technical Information of China (English)

    Li Chunguang; Shang Weirong

    1996-01-01

    @@ Dongying basin is a faulted basin rich in hydrocarbon and is under more exploration (wildcat well density is 0.155 well/km ) in the southern Bohai Bay area of China, covering an area of 5700 km. Based on the paleotopographic setting of Paleozoic basement rocks, the basin was evolved into Mesozoic and Cenozoic basin which was faulted in the north and overlapped in the south by the blockfaulting movement in J2-J3. So, each formation of the source rocks in Paleogene is characterized by thick deposit in the north and thin deposit in the south.

  3. Hack's law of debris-flow basins

    Institute of Scientific and Technical Information of China (English)

    LI Yong; YUE Z.Q.; LEE C.F.; BEIGHLEY R.E.; CHEN Xiao-Qing; HU Kai-Heng; CUI Peng

    2009-01-01

    Hack's law was originally derived from basin statistics for varied spatial scales and regions.The exponent value of the law has been shown to vary between 0.47 and 0.70,causing uncertainty in its application.This paper focuses on the emergence of Hack's law from debris-flow basins in China.Over 5,000 debris-flow basins in different regions of China with drainage areas less than 100km2 are included in this study.Basins in the different regions are found to present similar distributions.Hack's law is derived fi'om maximum probability and conditional distributions,suggesting that the law should describe some critical state of basin evolution.Results suggest the exponent value is approximately 0.5.Further analysis indicates that Hack's law is related to other scaling laws underlying the evolution of a basin and that the exponent is not dependent on basin shape but rather on the evolutionary stage.A case study of a well known debris-flow basin further confirms Hack's law and its implications in basin evolution.

  4. Estimation of subsurface formation temperature in the Tarim Basin, northwest China: implications for hydrocarbon generation and preservation

    Science.gov (United States)

    Liu, Shaowen; Lei, Xiao; Feng, Changge; Hao, Chunyan

    2016-07-01

    Subsurface formation temperature in the Tarim Basin, northwest China, is vital for assessment of hydrocarbon generation and preservation, and of geothermal energy potential. However, it has not previously been well understood, due to poor data coverage and a lack of highly accurate temperature data. Here, we combined recently acquired steady-state temperature logging data with drill stem test temperature data and measured rock thermal properties, to investigate the geothermal regime and estimate the subsurface formation temperature at depth in the range of 1000-5000 m, together with temperatures at the lower boundary of each of four major Lower Paleozoic marine source rocks buried in this basin. Results show that heat flow of the Tarim Basin ranges between 26.2 and 66.1 mW/m2, with a mean of 42.5 ± 7.6 mW/m2; the geothermal gradient at depth of 3000 m varies from 14.9 to 30.2 °C/km, with a mean of 20.7 ± 2.9 °C/km. Formation temperature estimated at the depth of 1000 m is between 29 and 41 °C, with a mean of 35 °C, while 63-100 °C is for the temperature at the depth of 3000 m with a mean of 82 °C. Temperature at 5000 m ranges from 97 to 160 °C, with a mean of 129 °C. Generally spatial patterns of the subsurface formation temperature at depth are basically similar, characterized by higher temperatures in the uplift areas and lower temperatures in the sags, which indicates the influence of basement structure and lateral variations in thermal properties on the geotemperature field. Using temperature to identify the oil window in the source rocks, most of the uplifted areas in the basin are under favorable condition for oil generation and/or preservation, whereas the sags with thick sediments are favorable for gas generation and/or preservation. We conclude that relatively low present-day geothermal regime and large burial depth of the source rocks in the Tarim Basin are favorable for hydrocarbon generation and preservation. In addition, it is found that the

  5. Estimation of subsurface formation temperature in the Tarim Basin, northwest China: implications for hydrocarbon generation and preservation

    Science.gov (United States)

    Liu, Shaowen; Lei, Xiao; Feng, Changge; Hao, Chunyan

    2015-10-01

    Subsurface formation temperature in the Tarim Basin, northwest China, is vital for assessment of hydrocarbon generation and preservation, and of geothermal energy potential. However, it has not previously been well understood, due to poor data coverage and a lack of highly accurate temperature data. Here, we combined recently acquired steady-state temperature logging data with drill stem test temperature data and measured rock thermal properties, to investigate the geothermal regime and estimate the subsurface formation temperature at depth in the range of 1000-5000 m, together with temperatures at the lower boundary of each of four major Lower Paleozoic marine source rocks buried in this basin. Results show that heat flow of the Tarim Basin ranges between 26.2 and 66.1 mW/m2, with a mean of 42.5 ± 7.6 mW/m2; the geothermal gradient at depth of 3000 m varies from 14.9 to 30.2 °C/km, with a mean of 20.7 ± 2.9 °C/km. Formation temperature estimated at the depth of 1000 m is between 29 and 41 °C, with a mean of 35 °C, while 63-100 °C is for the temperature at the depth of 3000 m with a mean of 82 °C. Temperature at 5000 m ranges from 97 to 160 °C, with a mean of 129 °C. Generally spatial patterns of the subsurface formation temperature at depth are basically similar, characterized by higher temperatures in the uplift areas and lower temperatures in the sags, which indicates the influence of basement structure and lateral variations in thermal properties on the geotemperature field. Using temperature to identify the oil window in the source rocks, most of the uplifted areas in the basin are under favorable condition for oil generation and/or preservation, whereas the sags with thick sediments are favorable for gas generation and/or preservation. We conclude that relatively low present-day geothermal regime and large burial depth of the source rocks in the Tarim Basin are favorable for hydrocarbon generation and preservation. In addition, it is found that the

  6. Relating petroleum system and play development to basin evolution: West African South Atlantic basins

    NARCIS (Netherlands)

    Beglinger, S.E.; Doust, H.; Cloetingh, S.A.P.L.

    2012-01-01

    Sedimentary basins can be classified according to their structural genesis and evolutionary history and the latter can be linked to petroleumsystem and playdevelopment. We propose an approach in which we use the established concepts in a new way: breaking basins down into their natural basin cycle d

  7. Fractal basin boundaries generated by basin cells and the geometry of mixing chaotic flows

    NARCIS (Netherlands)

    Nusse, HE; Yorke, JA

    2000-01-01

    Experiments and computations indicate that mixing in chaotic flows generates certain coherent spatial structures. Lf a two-dimensional basin has a basin cell (a trappings region whose boundary consists of pieces of the stable and unstable manifold of some periodic orbit) then the basin consists of a

  8. About the need of controlling the nitrogen oxides to reduce the formation of ozone in the metropolitan zone of Mexico city; Acerca de la necesidad de controlar las emisiones de oxidos de nitrogeno para reducir la formacion de ozono en la zona metropolitana de la ciudad de Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Torijano, E. F.; Vazquez, A. [Universidad Autonoma Metropolitana, Unidad Iztapalapa, Departamento de Ingenieria de Procesos e Hidraulica, Mexico, D. F. (Mexico)

    1995-12-31

    resultados se presentan en forma grafica, en ella se observa que si puede disminuirse la emision de oxidos de nitrogeno esto impactara directamente en la generacion de ozono. Ademas, se muestra la evolucion de otro producto derivado de la presencia de los oxidos de nitrogeno, el nitrato de peroxiacil, el cual es irritante de las mucosas respiratorias y los ojos. Con el auxilio de este modelo de simulacion se puede explorar el impacto derivado de acciones encaminadas a reducir la formacion de oxidos de nitrogeno y la liberacion de hidrocarburos en el nivel de ozono formado por efecto de la radiacion solar. Con base en lo anterior se puede analizar el impacto ecologico de acciones tales como: - mejorar el proceso de combustion en todos los dispositivos termicos - mejorar la calidad de los combustibles fosiles empleados - modificar ligeramente los habitos de operacion del sector industrial procurando que el uso intensivo de combustibles se desplace hacia las horas de la tarde y noche, cuando la incidencia solar es menor o nula.

  9. A tale of two basins: An integrated physical and biological perspective of the deep Arctic Ocean

    Science.gov (United States)

    Bluhm, B. A.; Kosobokova, K. N.; Carmack, E. C.

    2015-12-01

    domains have vertical stratification that constrains the transfer of nutrients to the surface layer (euphotic zone), thus leading to their oligotrophic state, particularly in the more strongly stratified Pacific Arctic where, despite high nutrient values in the inflow, convective reset of surface layer nutrients by haline convection in winter is virtually absent. First and multi-year sea ice drastically alters albedo and insulates the underlying water column from extreme winter heat loss while its mechanical properties (thickness, concentration, roughness, etc.) greatly affect the efficiency of momentum transfer from the wind to the underlying water. Biologically, sea ice algal growth in the basins is proportionally almost equal to or exceeding phytoplankton production, and is a habitat and transport platform for sympagic (ice-associated) fauna. Owing to nutrient limitation due to strong stratification and light limitation due to snow and ice cover and extreme sun angle, primary production in the two basin domains is very low compared to the adjacent shelves. Severe nutrient limitation and complete euphotic zone drawdown in the AB favors small phytoplankton, a ubiquitous deep chlorophyll maximum layer, a low f-ratio of new to recycled carbon fixation, and a low energy food web. In contrast, nutrients persist -albeit in low levels- in the western EB, even in summer, suggesting light limitation, heavy grazing or both. The higher stocks of nutrients in the EB are more conducive to marginal ice blooms than in the AB. The large-scale ocean currents (NHTC and ACBC) import substantial expatriate, not locally reproducing zooplankton biomass especially from the adjoining subarctic Atlantic (primarily Calanus finmarchicus), but also from the Pacific (e.g., Pseudocalanus spp., Neocalanus spp. and Metridia pacifica). These advective inputs serve both as source of food to resident pelagic and benthic biota within the basins, and as potential grazers exerting top down control on

  10. Tectonic evolution of Tarim basin in Cambrian-Ordovician and its implication for reservoir development, NW China

    Science.gov (United States)

    Bingsong, Yu; Zhuang, Ruan; Cong, Zhang; Yinglu, Pan; Changsong, Lin; Lidong, Wang

    2016-03-01

    In order to find the impact of regional tectonic evolution of Tarim basin on the inside distribution of sedimentary facies and reservoir development, this paper, based on the research of plate-tectonic evolution of Tarim basin, conducts an in-depth analysis on the basin's inside sedimentary response to the Eopaleozoic regional geodynamic reversion from extension to convergence around Tarim plate, and concludes that the regional geodynamic environment of surrounding areas closely contributes to the formation and evolution of paleo-uplifts, differentiation of sedimentary facies in platform, distribution of high-energy reef and bank facies belts, conversion of sedimentary base level from fall to rise, obvious change of lithology from dolomite to limestone, and formation of several unconformity surfaces in Ordovician system in the basin. A series of sedimentary responses in the basin are controlled by regional dynamic setting, which not only controls the distribution of reservoirs in reef and bank facies but also restricts the development and distribution of karst reservoirs controlled by the unconformity surfaces. This offers the macro geological evidences for us to further analyze and evaluate the distribution of favorable reservoirs.

  11. Seismic Characterization of the Jakarta Basin

    Science.gov (United States)

    Cipta, A.; Saygin, E.; Cummins, P. R.; Masturyono, M.; Rudyanto, A.; Irsyam, M.

    2015-12-01

    Jakarta, Indonesia, is home to more than 10 million people. Many of these people live in seismically non-resilient structures in an area that historical records suggest is prone to earthquake shaking. The city lies in a sedimentary basin composed of Quaternary alluvium that experiences rapid subsidence (26 cm/year) due to groundwater extraction. Forecasts of how much subsidence may occur in the future are dependent on the thickness of the basin. However, basin geometry and sediment thickness are poorly known. In term of seismic hazard, thick loose sediment can lead to high amplification of seismic waves, of the kind that led to widespread damage in Mexico city during the Michoacan Earthquake of 1985. In order to characterize basin structure, a temporary seismograph deployment was undertaken in Jakarta in Oct 2013- Jan 2014. A total of 96 seismic instrument were deployed throughout Jakarta were deployed throughout Jakarta at 3-5 km spacing. Ambient noise tomography was applied to obtain models of the subsurface velocity structure. Important key, low velocity anomalies at short period (<8s) correspond to the main sedimentary sub-basins thought to be present based on geological interpretations of shallow stratigraphy in the Jakarta Basin. The result shows that at a depth of 300 m, shear-wave velocity in the northern part (600 m/s) of the basin is lower than that in the southern part. The most prominent low velocity structure appears in the northwest of the basin, down to a depth of 800 m, with velocity as low as 1200 m/s. This very low velocity indicates the thickness of sediment and the variability of basin geometry. Waveform computation using SPECFEM2D shows that amplification due to basin geometry occurs at the basin edge and the thick sediment leads to amplification at the basin center. Computation also shows the longer shaking duration occurrs at the basin edge and center of the basin. The nest step will be validating the basin model using earthquake events

  12. Estado neoliberal y acumulación por desposesión a favor del capital glocal financiero

    Directory of Open Access Journals (Sweden)

    Marco Antonio Merchand Rojas

    2012-12-01

    Full Text Available El objetivo general de este trabajo es analizar por qué la acumulación por desposesión es una de lasmodalidades que se implementan indiscriminadamente en todos los órdenes de la economía mundial y representa la mejor forma para estabilizar el sistema capitalista a favor del capital financiero y en contra de la fuerza de trabajo. Las condiciones en que el capital se impone en cada espacio económico difieren en sus métodos y maneras de reproducirse; no obstante su carácter intrínseco de enajenar o externalizar lo internalizado en beneficio de pocos (sobre todo, de los dueños del capital se aplica por igual en todos los países, independientemente de si estamos hablado de un país de grado alto o bajo de desarrollo

  13. Dispersal limitation favors more fecund species in the presence of fitness-equalizing demographic trade-offs.

    Science.gov (United States)

    Zhou, Shurong; Peng, Zechen; Zhang, Da-Yong

    2015-05-01

    Demographic equivalence is the central assumption of the neutral theory of species diversity and has attracted much criticism, since species clearly differ from each other in many traits. Two simple answers--that is, dispersal limitation and demographic trade-offs--have been suggested to resolve this problem. Both processes are considered to be capable of making interspecific differences in fitness smaller on their own, thus potentially reconciling neutrality with reality. However, when the two mechanisms operate simultaneously, as they must do in natural communities, we are surprised to find that they interfere with each other in such a way that dispersal limitation favors more fecund species. Fitness equivalence is no longer guaranteed by a perfect trade-off, and contrary to popular belief, dispersal limitation is found to impede rather than facilitate the stochastic coexistence of species. Still, more species can coexist than allowed through demographic equivalence, providing a potentially alternative explanation for biodiversity maintenance in nature. PMID:25905505

  14. Poleward displacement of coastal upwelling-favorable winds in the ocean's eastern boundary currents through the 21st century

    Science.gov (United States)

    Rykaczewski, Ryan R.; Dunne, John P.; Sydeman, William J.; García-Reyes, Marisol; Black, Bryan A.; Bograd, Steven J.

    2015-08-01

    Upwelling is critical to the biological production, acidification, and deoxygenation of the ocean's major eastern boundary current ecosystems. A leading conceptual hypothesis projects that the winds that induce coastal upwelling will intensify in response to increased land-sea temperature differences associated with anthropogenic global warming. We examine this hypothesis using an ensemble of coupled, ocean-atmosphere models and find limited evidence for intensification of upwelling-favorable winds or atmospheric pressure gradients in response to increasing land-sea temperature differences. However, our analyses reveal consistent latitudinal and seasonal dependencies of projected changes in wind intensity associated with poleward migration of major atmospheric high-pressure cells. Summertime winds near poleward boundaries of climatological upwelling zones are projected to intensify, while winds near equatorward boundaries are projected to weaken. Developing a better understanding of future changes in upwelling winds is essential to identifying portions of the oceans susceptible to increased hypoxia, ocean acidification, and eutrophication under climate change.

  15. NO synthesis from arginine is favored by α-linolenic acid in mice fed a high-fat diet.

    Science.gov (United States)

    Hermier, Dominique; Guelzim, Najoua; Martin, Pascal G P; Huneau, Jean-François; Mathé, Véronique; Quignard-Boulangé, Annie; Lasserre, Frédéric; Mariotti, François

    2016-09-01

    Alterations in NO availability and signaling play a pivotal role at early stages of the metabolic syndrome (MetSynd). We hypothesized that dietary α-linolenic acid (ALA, 18:3 n-3) favors NO availability by modulating amino acid metabolism, with a specific impact on the arginine-NO pathway. Mice were fed a hyperlipidic diet (285 g lipid/kg, 51.1 % energy), rich in either saturated fatty acids (SFA, provided by palm oil, PALM group) or ALA (provided by linseed oil, LIN group). We measured whole-body NO synthesis and systemic arginine hydrolysis with a tracer-based method, plasma concentration of related metabolites, and hepatic mRNA level of related enzymes, and the study was completed by a transcriptomic analysis in the liver. As expected with this model, hyperlipidic diets resulted in increased adiposity and glycemia after 5 weeks. As compared to PALM mice, LIN mice had a higher plasma nitrite and nitrate concentration, a higher whole-body conversion of arginine into NO vs urea, and a similar plasma concentration of asymmetric dimethylarginine (ADMA), despite a higher expression of the liver dimethylargininase-1. In LIN mice, there was a higher expression of genes involved in PPARα signaling, but a little impact on gene expression related to amino acids and arginine metabolism. This effect cannot be directly ascribed to changes in arginase activity in the liver or ADMA metabolism, nor to direct regulation of the related target genes. In conclusion, dietary ALA favors NO synthesis, which could contribute to rescue NO availability when jeopardized by the nutritional conditions in relation with the initiation of the MetSynd. PMID:27178023

  16. Linking basin evolution to plate tectonic processes in (northern) Africa

    OpenAIRE

    Gravråk, Mariann

    2011-01-01

    Several sedimentary basins in Africa are classified as intracratonic basins, but no conclusive formation mechanism has been identified for these basin types. Tectonic subsidence curves may help in unraveling formation mechanisms or identify tectonic forcing for these basins. This thesis presents and analyses basin subsidence curves for basins in the interior of Africa and near its passive margins. A backstripping program has been written to solve the backstripping equations needed to make the...

  17. Normal Fault Basin Geometries From Gravity Analyses in the La Paz - Los Cabos Region, Baja California Sur, Mexico

    Science.gov (United States)

    Busch, M. M.; Coyan, J. A.; Arrowsmith, J. R.; Umhoefer, P. J.; Martinez-Gutierrez, G.

    2008-12-01

    The southern cape region of the Baja California peninsula is ruptured by an array of roughly north-striking, left-stepping active normal faults, which accommodate regional transtension. Dominant faults within this system include the Carrizal, San Juan de los Planes (SJP) (and offshore Espiritu Santo fault), La Gata, and San Jose del Cabo (SJC) faults. We conducted gravity surveys across the basins bounded by these faults to gain insight into fault slip rates and basin evolution to better understand the role of upper-crustal processes during development of an obliquely rifted plate margin. The geodetic location of each gravity observation station was measured to cm-scale accuracy with real-time kinematic GPS and the relative gravity was measured with a LaCoste and Romberg Model G gravity meter to an accuracy of 0.01 mgal. Gravity data were modeled as a 2D two-layer model with a bedrock density of 2.67 g/cm3 and a basin fill density of 2.1 or 2.2 g/cm3. The hanging wall of the east-dipping Carrizal fault hosts the La Paz basin. In the subsurface, this basin is a half-graben that is manifest as two smaller basins (few hundred meters deep) separated by a bedrock high, which likely reflects the two main east-dipping splays (Carrizal and Centenario faults). The SJP basin is a graben bound by the SJP fault on the west and the La Gata fault on the east and has a modeled maximum depth of approximately 1.5 km. This basin is marked by a series of relict normal faults dipping toward the basin center. The maximum depth to bedrock is just northwest of center, asymmetric toward the SJP fault, indicating that slip may be greater along the SJP than along the La Gata fault. It might also mark the possible location of basin inception, indicating that as the basin evolved, faulting moved outward to the presently active SJP and La Gata Faults. The SJC basin has a maximum depth of approximately 2.5 km. The favored gravity model depicts the SJC basin as resulting from slip along a series

  18. Red River Basin Mapping 2008-2010

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — This LiDAR data covers the Red River Basin with portions of ND, MN, SD and flows into Canada. The US Red River Basin boudnary covers 40,860 sqmi,with the additional...

  19. The structure of Nansen and Amundsen Basin

    Science.gov (United States)

    Micksch, U.; Jokat, W.

    2003-04-01

    During the AMORE expedition in August/September 2001, a US-German joint project, the Gakkel Ridge and the adjoining basins were investigated. In this contribution we report on the results of the seismic investigations in the Nansen Basin as well as in the Amundsen Basin. We obtained two almost parallel profiles through the Nansen Basin from the northeastern continental margin of Svalbard (29°E and 32°E) to the Gakkel Ridge at 17°E and 21°E. To investigate the Amundsen Basin, we left Gakkel Ridge at about 70°E towards Lomonossov Ridge for another transect. In total 1360 km of seismic reflection data with very good data quality were recorded. Parallel to the seismic reflection transects up to 30 sonobuoys were deployed. The data from both basins shows striking differences in the basement topography. While in the Nansen Basin the oceanic crust is more or less continuously shallowing, this is not the case in the Amundsen Basin. This points to some asymmetric spreading history of the Gakkel Ridge in northern and southern directions. Some of the Sonobuoys recorded also weak arrivals from the Moho discontinuity. The analysis of the wide angle and gravity data shows, that there are areas with a significant thinning of the oceanic crust. Results of the reflection and refraktion seismic as well as the gravity interpretation will be presented.

  20. Hydrological research basins and the environment

    NARCIS (Netherlands)

    1990-01-01

    The International Conference on Hydrological Research Basins and the Environment, was held at Wageningen from September 24th to 28th. The conference was organized by the Committee of the European Network of Experimental and Representative Basins and the National Committee of the Netherlands for the

  1. The karst hydrogeology of upper Ermenek Basin

    International Nuclear Information System (INIS)

    The karst hydrogeology of the Upper Ermenek Basin whose surface area is about 2050 km2 is investigated within the framework of this study. The investigation comprised mainly the study of the characteristics of karstification in the basin and the role of the karstic features on the regional hydrodynamic structure. regional hydrodynamic structure

  2. K-Basin isolation barrier seal

    International Nuclear Information System (INIS)

    This report documents various aspects of the design, analysis, procurement, and fabrication of the hydraulic seal on the isolation barriers to be installed in the 100-K Area spent nuclear fuel basin. The isolation barrier is used to keep water in the basin in the event of an earthquake

  3. HYDROGEOLOGICAL INVESTIGATIONS OF SANDIKLI BASIN (AFYONKARAHISAR)-PRELIMINARY STUDIES

    OpenAIRE

    Seyman Aksever, Arş. Gör. Fatma; Davraz, Doç.Dr.Ayşen; Karagüzel, Prof.Dr.Remzi

    2011-01-01

    ABSTRACT The aims of this research are to determine hydrogeological and hydrogeochemical investigations of Sandıklı (Afyonkarahisar) basin and to plan of optimum groundwater management of the basin. The Sandıklı basin is situated in the west of the Aegean region and discharge to the Büyük Menderes Basin. The research area is occurred from Sandıklı Kuruçay basin and Küçük Sincanlı basin. It has 1556 km2 recharge area. The basin has a semi-closed basin property due to discharge to Kestel Ri...

  4. Basin Fluid Mineralization during Multistage Evolution of the Lanping Sedimentary Basin, Southwestern China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The Lanping sedimentary basin has experienced a five-stage evolution since the late Paleozoic: ocean-continent transformation (late Paleozoic to early mid-Triassic); intracontinental rift basin (late mid-Triassic to early Jurassic); down-warped basin (middle to late Jurassic); foreland basin (Cretaceous); and strike-slip basin (Cenozoic). Three major genetic types of Ag-Cu polymetailic ore deposits, including the reworked hydrothermal sedimentary, sedimentary-hydrothermally reworked and hydrothermal vein types, are considered to be the products of basin fluid activity at specific sedimentary-tectonic evolutionary stages. Tectonic differences of the different evolutionary stages resulted in considerable discrepancy in the mechanisms of formation-transportation, migration direction and emplacement processes of the basin fluids, thus causing differences in mineralization styles as well as in genetic types of ore deposit.

  5. The influence of the geomorphological factors on the relief modelling within Eselnita hydrographic basin (Danube catchment/Romania

    Directory of Open Access Journals (Sweden)

    DANIELA VLAD

    2012-08-01

    Full Text Available Developed on the south-eastern side of Almãjului Mountains, Eşelniţa drainage basin neighbours upon the following basins: upon S – SV with Mala, upon SV - V with Mraconia, upon V – NV with Berzasca, upon NV - NNE with Nera and on the NNE – SE direction with Cerna. The basin has a surface of 77 km2 and present a 5th degree hydrographic network according to Horton-Strahler ranking system, tributary to Danube by means of Eşelniţa main collector. Developed in a mountain landscape, the basin presents different levels held between minimum altitude of 64 m at the confluence with the Danube and maximum altitude of 1107 m, thus presenting a difference of 1043 m. Geological formations within the basin belong predominant to the Danubian Domain, so in central and upper courses, these are represented by a crystalline foundation and by magmatic rocks of intrusive nature covered by very small areas of sediment located in the northwest (belong to the Lower Jurassic and in the south-eastern (belongs to the Upper Cretaceous of the basin. But in the lower course, there are both crystalline and the sedimentary formations, last being integrated to Orşova depression and whose presence is related to the evolution of the Danube. Morphometric indices of Eşelniţa basin allows the distinction of a higher sector, mountainous terrain with high energy under a relatively increased fragmentation and depression sector with low relief energy and also with an intense fragmentation of the existing sedimentary rocks wich favors erosion manifestation in the context of deforestation action.

  6. Nature of the uppermost mantle below the Porcupine Basin, offshore Ireland: new insights from seismic refraction and gravity data modeling

    Science.gov (United States)

    Prada, M.; Watremez, L.; Chen, C.; O'Reilly, B.; Minshull, T. A.; Reston, T. J.; Wagner, G.; Gaw, V.; Klaeschen, D.; Shannon, P.

    2015-12-01

    The Porcupine Basin is a tongue-shaped basin SW of Ireland formed during the opening of the North Atlantic Ocean. Its history of sedimentation reveals several rifting and subsidence phases during the Late Paleozoic and Cenozoic, with a particular major rift phase occurring in Late Jurassic-Early Cretaceous times. Previous work, focused on seismic and gravity data, suggest the presence of major crustal faulting and uppermost mantle serpentinization in the basin. Serpentinization is a key factor in lithospheric extension since it reduces the strength of mantle rocks, and hence, influences the tectonics of the lithosphere. Besides reducing the seismic velocity of the rock, serpentinization decreases mantle rock density favoring isostatic rebound and basin uplift, thus affecting the tectonic and thermal evolution of the basin. Here we characterize the deep structure of the Porcupine Basin from wide-angle seismic (WAS) and gravity data, with especial emphasis on the nature of the underlying mantle. The WAS data used were acquired along a 300 km long transect across the northern region of the basin. We used a travel time inversion method to model the data and obtain a P-wave velocity (Vp) model of the crust and uppermost mantle, together with the geometry of the main geological interfaces. The crustal structure along the model reveals a maximum stretching factor of ~5-6. These values are well within the range of crustal extension at which the crust becomes entirely brittle allowing the formation of major crustal faulting and serpentinization of the mantle. To further constrain the seismic structure and hence the nature of the mantle we assess the Vp uncertainty of the model by means of a Monte Carlo analysis and perform gravity modeling to test different interpretations regarding mantle rock nature. This project is funded by the Irish Shelf Petroleum Studies Group (ISPSG) of the Irish Petroleum Infrastructure Programme Group 4.

  7. Petroleum geology of the Melut Basin and the Great Palogue Field, Sudan

    Energy Technology Data Exchange (ETDEWEB)

    Dou, Lirong; Xiao, Kunye; Li, Zhi [China National Oil and Gas Exploration and Development Corporation, Beijing (China); Cheng, Dingsheng [Research Institute of Petroleum Exploration and Development (RIPED), Beijing (China); Shi, Buqing [China National Oil and Gas Exploration and Development Corporation, Beijing (China); Research Institute of Petroleum Exploration and Development (RIPED), Beijing (China)

    2007-03-15

    This paper overviews the framework, structural and petroleum geology aspects of the Melut rift Basin in Sudan. The data base is from mainly proprietary exploration work consisting of more than 20,000 km of seismic profiles, 2000 km{sup 2} of 3D seismic, and more than 50 exploration wells. There have been more than 15 oil and oil and gas discoveries. The Melut Basin is a Meso-Cenozoic rift basin accompanied by the formation and development of the Central African Shear Zone (CASZ) on the pre-Cambrian crystalline and metamorphic basement of lower relief. Three stages of rift development and fracturing have been identified, stronger in the Early Cretaceous and Paleogene and weaker in the Late Cretaceous. Source rocks are the Lower Cretaceous lacustrine shales, whereas reservoirs and seals are both Paleogene and Upper Cretaceous. Dominant structural styles are large-scale anticlines in the Paleogene sequences and antithetic normal fault-blocks in the Upper Cretaceous and Paleogene. Heavy to light oils (8.87-61.5 API) and gas have been discovered in the Paleogene and only light oils and gas in the Upper Cretaceous pay zones. The primary pay zone in the Melut Basin is the Paleogene. The Great Palogue Field, with ultimate recoverable oil reserves of more than 900 million barrels, was discovered in the northern Melut Basin. The gentle slopes of each subbasin are favorable areas for petroleum accumulation and enrichment. The faulted anticlines within the Paleogene syn-rift sequences are the main trap types, whereas the antithetic fault-blocks of the Upper Cretaceous sequences are secondary. (author)

  8. Application of Fluid Inclusions in the Study of Natural Gas Geology in Ordos Basin

    Institute of Scientific and Technical Information of China (English)

    FAN Ai-ping; YANG Ren-chao; FENG Qiao; LIU Yi-qun; HAN Zuo-zhen

    2006-01-01

    The new recently demonstrated reserves of oil and gas in the Ordos basin are found at the top of petroliferous basins in China. Gas pools discovered in recent years in the Permian system have become the main natural gas resource in the basin. Therefore, synthetic research on fluid inclusions should be done in order to ascertain the pool-forming stage, the maturity of organic matters and the properties of Paleo-fluids. The main types of fluid inclusions in the Permian system in the basin include brine inclusions, carbon dioxide inclusions and organic inclusions. Homogenization temperatures (HT) of brine inclusions can be divided into four intervals: 66-83 ℃, 86-108 ℃, 112-138 ℃ and 142-153 ℃. The fluid inclusions in the interval of 112-138 ℃ are much more than that of other intervals, indicating that the second stage of hydrocarbon migration associated with the third temperature interval is the most important stage of gas pool formations. The fluid inclusion has extensive applications in the study of gas geology, not only in ascertaining the formation stage of gas pools, but also in estimating the maturity of organic matter and restoring Paleo-fluids. The result of testing the HT of brine inclusions shows that there are two stages of gas pool formations in the Permian system occurring ±150 Ma and ±100 Ma. The maturity of organic matter is moderate to high, a conclusion based on the color of fluid inclusions (radiated by fluorescence). The high salinity of Paleo-fluids of the NaCl-H2O and CaCl2-H2O systems shows good preservation conditions of the Paleo-fluids. Two stages of reservoir filling, high maturity of organic matter and good preservation conditions are factors favorable for the formation and preservation of large-scale gas pools in the Permian system in the Ordos basin.

  9. The flora of Early Permian coal measures from the Parana Basin in Brazil: A review

    Energy Technology Data Exchange (ETDEWEB)

    Iannuzzi, Roberto [Centro de Investigacoes do Gondwana, Instituto de Geociencias, Universidade Federal do Rio Grande do Sul, Av. Bento Goncalves, 9500, Porto Alegre, RS, 91.509-900 (Brazil)

    2010-08-01

    This paper presents an updated overview integrating both previous and newly published data on the most important floras found associated with Early Permian coal seams in the Parana Basin, Brazil. These floras occur within the Rio Bonito Formation and correspond to the Gondwana ''Glossopteris Flora.'' For this review, five floras are selected, in ascending stratigraphic order: the ''Sao Joao do Triunfo,'' ''Figueira,'' ''Quiteria,'' ''Morro do Papaleo'' and ''Irapua Bed'' floras. They are the best-known floras of the basin in terms of taxonomic composition, paleoecology and environments of deposition. An early-mid Sakmarian to earliest Artinskian age is indicated for the Rio Bonito Formation based on absolute radiometric and relative biostratigraphic ages. Integration of available information about the selected floras allows evaluation of taphonomic and paleoecological factors to provide a more comprehensive understanding of the Early Permian floral record in the Parana Basin. The variation observed in both the taxonomic composition of individual floras and in the frequency of occurrence of different plant groups is due to the broad range of environmental/edaphic conditions that prevailed in the many different depositional settings represented in the Rio Bonito Formation. A more precise age determination obtained for the plant-bearing deposits permits the establishment of a more confident correlation between the Early Permian floral succession in the Parana Basin and other Early Permian floral successions in other basins. The Sakmarian global warming favored the appearance of pecopterid and sphenopterid ferns amongst the spore-producing plants, and the glossopterids amongst the pollen-producing plants. (author)

  10. Neotectonic of subsiding basins : case of studies from Marañon and Beni basins, Peru and Bolivia

    OpenAIRE

    Dumont, Jean-Francois

    1994-01-01

    Climatic conditions make the fluvial processes very sensitive in the extended flood plain of subandean basins, giving typical morphostructures. Because of high subsidence rate, these basins are case for the understanding of neotectonics in subsiding basins. Recent anciente fluvial traces are used in combination with sub surface structures, neotectonic and seismotectonic data to study the neotectonic evolution of the Peruvian and Bolivian active foreland basins. These basins, the Marañon Basin...

  11. Implementing Integrated River Basin Management in China

    Directory of Open Access Journals (Sweden)

    Lifeng Li

    2010-06-01

    Full Text Available This paper examines the role of the World Wildlife Fund for Nature China as policy entrepreneur in China. It illustrates the ways in which the World Wildlife Fund for Nature is active in promoting integrated river basin management in the Yangtze River basin and how the efforts at basin level are matched with the advice of the China Council for International Cooperation on Environment and Development task force on integrated river basin management to the national government of China. This article demonstrates that the World Wildlife Fund for Nature uses various strategies of different types to support a transition process towards integrated river basin management. Successful deployment of these strategies for change in environmental policy requires special skills, actions, and attitudes on the part of the policy entrepreneur, especially in China, where the government has a dominant role regarding water management and the position of policy entrepeneurs is delicate.

  12. 105-KE basin pilot run relocation

    International Nuclear Information System (INIS)

    The purpose of this document is to present the bases for selecting the exact in-facility location for installation of process equipment to support pilot testing activities in the 105-KE Basin at the United States Department of Energy Hanford Site, in southeastern Washington State. The 105-KE Basin was constructed during the early 1950s, as an integralcomponent of the 105-K East reactor building. Similar basins were provided in all Hanford weapons production reactor buildings to receive fuel elements discharged from the reactors and stage them for rail transport to 200 Area fuel reprocessing plants. The 105-KE reactor began operation in 1955. It was shut down in 1971. However, the 105-KE Basin was reactivated several years later to store spent fuel from the N-Reactor basin and permit its continued operation during outages at the Plutonium Uranium Extraction (PUREX) plant in the 200E Area

  13. K-Basins isolation barriers summary report

    International Nuclear Information System (INIS)

    The purpose of this report is to provide an information summary for the 100-K Area fuel storage basins design change. The design change was made to resolve an unreviewed safety question related to potential water leakage from the basin following a design basis earthquake. The design change consists of installing isolation barriers in the K-East and K-West Basins. The barriers are installed in each basin to isolate the fuel storage portion of the basin from the location of the potential seismic induced leak. The summary represented by this report provides information on the issue, the courses of corrective action, the technical work to support the corrective action, and the fabrication, installation, testing of the isolation barriers

  14. Estimation of production characteristic curves of geothermal wells and of the permeability of rocky formations through one single mass flow-pressure-enthalpy (W-P-h) measurement at the wellhead; Estimacion de curvas caracteristicas de produccion de pozos geotermicos y de permeabilidades de formaciones rocosas a partir de una sola medicion flujo masico-presion- entalpia (W-P-h) a boca de pozo

    Energy Technology Data Exchange (ETDEWEB)

    L Moya, Sara; Aragon, Alfonso [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1997-12-31

    The proposed methodology described ahead (Moya et al.,1996; Moya et al.,1997a, 1997b and 1997c) simplifies the construction of production characteristic curves of geothermal wells and of its associated thermal productivity, in requiring one single measurement of mass flow-pressure-enthalpy (W-P-h) at the wellhead. Therefore it is an ecological option, technically and economically more feasible. On the other hand, the methodology also allows to diagnose the rocky formation absolute permeability in the well feeding zone. This permeability is usually determined through well bottom pressure tests, than in some cases are difficult to interpret. The permeability inferred by means of the proposed technology represents a complementary tool for these field tests and for the laboratory measurements on drilling cores. [Espanol] La metodologia propuesta que se describe a continuacion [Moya et al., 1995d; Moya et al., 1996; Moya et al., 1997a, 1997b y 1997c] simplifica la construccion de curvas caracteristicas de produccion de pozos geotermicos y de su productividad termica asociada al requerir solo una medicion de flujo masico-presion-entalpia (W-P-h) a boca de pozo. Es por tanto una alternativa ecologica, tecnica y economicamente mas factible. Por otra parte, la metodologia tambien permite diagnosticar el valor de la permeabilidad absoluta de la formacion rocosa en la zona de alimentacion al pozo. Esta permeabilidad se determina usualmente a partir de pruebas de presion a fondo de pozo que en algunos casos son dificiles de interpretar. La permeabilidad inferida mediante la metodologia propuesta representa una herramienta complementaria a estas pruebas de campo y a las mediciones de laboratorio sobre nucleos de perforacion.

  15. The influence of preexisting structure and halokinesis on organic matter preservation and thrust system evolution in the Ionian Basin, Northwest Greece

    Energy Technology Data Exchange (ETDEWEB)

    Karakitsios, V. [Univ. of Athens (Greece)

    1995-07-01

    The opening of the Ionian basin and its internal differentiation is attested to by lateral facies and thickness variations of the formations deposited during the Pliensbachian and Tithonian (synrift formations). The beginning of the synrift sequence is represented by the Siniais Limestones (Pliensbachian) and their lateral equivalent, the Louros Limestones. The geometric characteristics of the extensional basin depend on both extension related to the latest opening of the Tethys ocean and halokinesis of the Ionian zone evaporitic substratum. The accumulation of organic matter in the {open_quotes}Lower and Upper Posidonia beds{close_quotes} of the Ionian zone during the Toarcian and Tithonian is directly related to the geometry of the synrift period of the Ionian basin. Restricted subbasins were formed where the geometry of the basin favored stagnation and consequently the locally euxinic conditions of bottom waters. Anoxic conditions persisted locally to the postrift period in areas where the {open_quotes}Upper Siliceous Zone{close_quotes} (Albian-Cenomanian) of the Vigla Limestones is well developed; these areas probably represent subbasins that were preserved by the continuation of halokinetic movements during the postrift period. During the early Miocene Alpine orogeny, collision-related compressive stresses on the margin induced the reactivation of preexisting fractures, which were responsible for the inversion tectonics that affected the Mesozoic basin. The geometric characteristics of the inverted basin were dependent on lithology (evaporates), geometry of the extensional structures, and direction of the compressional phase. The geological evolution in the Ionian basin is an example of inversion tectonics of a basin with an evaporitic substratum. The opening of the Ionian basin and the inversion tectonics influence both the source rocks and the probable hydrocarbon traps of the Ionian zone.

  16. Variations of fluvial tufa sub-environments in a tectonically active basin, Pleistocene Teruel Basin, NE Spain

    Science.gov (United States)

    Camuera, Jon; Alonso-Zarza, Ana M.; Rodríguez-Berriguete, Álvaro; Meléndez, Alfonso

    2015-12-01

    The Pleistocene Tortajada fluvial deposit occurs in the eastern active margin of the Teruel Basin. It developed in the early stages of opening of the basin and at present is disconnected to the Alfambra River. The preserved deposits show that the fluvial system consisted in three different sub-environments including: Upper Terraces, Ponds and Cascades. The main facies are framestones of stems, phytoclastic rudstone, framestone of bryophytes, peloidal and filamentous stromatolites, mudstone and detrital (conglomerates and slope-breccias) facies. These facies are arranged in three different sequence types, all of them showing a lower detrital term followed by pond and, in cases, cascade deposits. The microfacies analyses reveal that both biotic and abiotic processes performed an important role in the deposition within the river. Isotopic analyses (δ18O from - 8.58‰ to - 6.70‰ VPDB and δ13C from - 7.44‰ to - 3.97‰ VPDB) are indicative of meteoric water within a hydrologically open system. The carbonate hinterland rocks, together with a semi-arid to sub-humid climate favored carbonate accumulation within the river. Our results point out that the location, morphology and sedimentary sequences of the Tortajada fluvial system had an important tectonic control. The situation of the main and secondary faults controlled the paleomorphology of the river floor. Thus cascades are found in areas of important step faults, whereas the spaces between faults were occupied by fluviatile/lacustrine areas. In addition the development of the different sedimentary sequences was also a reflection of movements of these faults. In short, our study may confirm that tectonism is an important control on tufa development.

  17. Morphostructural characterization of the Charco basin and its surrounding areas in the Chihuahua segment of north Mexican Basin and Range Province

    Science.gov (United States)

    Troiani, Francesco; Menichetti, Marco

    2014-05-01

    based on aerial photos and Digital Elevation Models (a 28x28 m DEM and high-resolution LIDAR dataset in key sites), and iii) geophysical investigations (high resolution reflection seismic profiling combined with refraction seismic tomography). The main outputs of this research are as follows: i) the Charco basin master-faults and their conjugate extensional system were geometrically characterized and their main associated landforms mapped and described; ii) the morphostratigraphic correlations amongst both deformed and tectonically unaffected Quaternary deposits revealed that the Charco basin master fault has been inactive over the Holocene; iii) the main extensional fault system is associated with conjugate faults, oriented approximately SSW-NNE, that segmented the Charco basin master faults and favored the deposition of the most recent piedmont fans along the eastern margin of the basin; iv) the local morphostructures had played a dominant influence on the Quaternary evolution of both drainage network and relief landforms.

  18. Avaliação de genótipos de triticale e trigo em ambientes favoráveis e desfavoráveis no Estado de São Paulo Evaluation of triticale and wheat genotypes under favorable and unfavorable environments in the State of São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    JOÃO CARLOS FELICIO

    2001-01-01

    Full Text Available Avaliou-se a adaptação de 18 genótipos de triticale e dois de trigo em experimentos instalados em dois ambientes, na Estação Experimental de Agronomia do Instituto Agronômico, localizada em Mococa (SP, no período de 1996-99. No primeiro ambiente, aplicou-se a irrigação por aspersão em condição de sequeiro (favorável e, no segundo, várzea úmida com irrigação por inundação (desfavorável. A diversidade entre os ambientes propiciou diferença entre os padrões de resposta dos genótipos. No ambiente irrigado por aspersão, houve maior produtividade para ambas as espécies, sendo o genótipo de triticale TATU 4/ARDI 1 o que apresentou o melhor rendimento de grãos. Na várzea úmida, destacou-se o triticale LT 978.82/ASAD//TARASCA. O IAC 60 (trigo apresentou grande variação no rendimento de grãos de um ano para outro, nas condições de várzea. O ciclo das plantas, da emergência ao espigamento, foi mais longo entre os genótipos de triticale nas condições de várzea úmida, quando comparado ao cultivo irrigado por aspersão. Esses resultados indicam que os genótipos de trigo apresentam adaptação específica para o ambiente de sequeiro com irrigação por aspersão, e o grupo de genótipos de triticale, adaptação mais ampla.The environment adaptation of eighteen triticale and two wheat genotypes were evaluated in experiments carried out at two different sites of the Mococa Agronomy Experimental Station, São Paulo State, Brazil, in the period 1996-99. The favorable environment was provided with sprinkler irrigation on an upland; the unfavorable condition consisted of a moist flat area with basin irrigation system. The environment diversity induced different genotypes response patterns. Under the sprinkler irrigation system the yields were higher for both species, but the triticale genotype TATU 4/ARDI 1 presented the highest grain yield. Under moist and flat area condition the triticale LT 978.82/ASAD//TARASCA showed

  19. High-Dose-Rate Brachytherapy as a Monotherapy for Favorable-Risk Prostate Cancer: A Phase II Trial

    International Nuclear Information System (INIS)

    Purpose: There are multiple treatment options for favorable-risk prostate cancer. High-dose-rate (HDR) brachytherapy as a monotherapy is appealing, but its use is still investigational. A Phase II trial was undertaken to explore the value of such treatment in low-to-intermediate risk prostate cancer. Methods and Materials: This was a single-institution, prospective study. Eligible patients had low-risk prostate cancer features but also Gleason scores of 7 (51% of patients) and stage T2b to T2c cancer. Treatment with HDR brachytherapy with a single implant was administered over 2 days. One of four fractionation schedules was used in a dose escalation study design: 3 fractions of 10, 10.5, 11, or 11.5 Gy. Patients were assessed with the Common Terminology Criteria for Adverse Events version 2.0 for urinary toxicity, the Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer scoring schema for rectal toxicity, and the Expanded Prostate Cancer Index Composite (EPIC) questionnaire to measure patient-reported health-related quality of life. Biochemical failure was defined as a prostate-specific antigen (PSA) nadir plus 2 ng/ml. Results: Between 2003 and 2008, 79 patients were enrolled. With a median follow-up of 39.5 months, biochemical relapse occurred in 7 patients. Three- and 5-year actuarial biochemical control rates were 88.4% (95% confidence interval [CI], 78.0-96.2%) and 85.1% (95% CI, 72.5-94.5%), respectively. Acute grade 3 urinary toxicity was seen in only 1 patient. There was no instance of acute grade 3 rectal toxicity. Rates of late grade 3 rectal toxicity, dysuria, hematuria, urinary retention, and urinary incontinence were 0%, 10.3%, 1.3%, 9.0%, and 0%, respectively. No grade 4 or greater toxicity was recorded. Among the four (urinary, bowel, sexual, and hormonal) domains assessed with the EPIC questionnaire, only the sexual domain did not recover with time. Conclusions: HDR brachytherapy as a monotherapy for favorable

  20. High-Dose-Rate Brachytherapy as a Monotherapy for Favorable-Risk Prostate Cancer: A Phase II Trial

    Energy Technology Data Exchange (ETDEWEB)

    Barkati, Maroie [Division of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne (Australia); Williams, Scott G., E-mail: scott.williams@petermac.org [Division of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne (Australia); Department of Pathology, University of Melbourne, Melbourne (Australia); Foroudi, Farshad; Tai, Keen Hun; Chander, Sarat [Division of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne (Australia); Department of Pathology, University of Melbourne, Melbourne (Australia); Dyk, Sylvia van [Division of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne (Australia); See, Andrew [Ballarat Austin Radiation Oncology Centre, Ballarat (Australia); Duchesne, Gillian M. [Division of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne (Australia); Department of Pathology, University of Melbourne, Melbourne (Australia)

    2012-04-01

    Purpose: There are multiple treatment options for favorable-risk prostate cancer. High-dose-rate (HDR) brachytherapy as a monotherapy is appealing, but its use is still investigational. A Phase II trial was undertaken to explore the value of such treatment in low-to-intermediate risk prostate cancer. Methods and Materials: This was a single-institution, prospective study. Eligible patients had low-risk prostate cancer features but also Gleason scores of 7 (51% of patients) and stage T2b to T2c cancer. Treatment with HDR brachytherapy with a single implant was administered over 2 days. One of four fractionation schedules was used in a dose escalation study design: 3 fractions of 10, 10.5, 11, or 11.5 Gy. Patients were assessed with the Common Terminology Criteria for Adverse Events version 2.0 for urinary toxicity, the Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer scoring schema for rectal toxicity, and the Expanded Prostate Cancer Index Composite (EPIC) questionnaire to measure patient-reported health-related quality of life. Biochemical failure was defined as a prostate-specific antigen (PSA) nadir plus 2 ng/ml. Results: Between 2003 and 2008, 79 patients were enrolled. With a median follow-up of 39.5 months, biochemical relapse occurred in 7 patients. Three- and 5-year actuarial biochemical control rates were 88.4% (95% confidence interval [CI], 78.0-96.2%) and 85.1% (95% CI, 72.5-94.5%), respectively. Acute grade 3 urinary toxicity was seen in only 1 patient. There was no instance of acute grade 3 rectal toxicity. Rates of late grade 3 rectal toxicity, dysuria, hematuria, urinary retention, and urinary incontinence were 0%, 10.3%, 1.3%, 9.0%, and 0%, respectively. No grade 4 or greater toxicity was recorded. Among the four (urinary, bowel, sexual, and hormonal) domains assessed with the EPIC questionnaire, only the sexual domain did not recover with time. Conclusions: HDR brachytherapy as a monotherapy for favorable

  1. The favorable impact of PIK3CA mutations on survival: an analysis of 2587 patients with breast cancer

    Institute of Scientific and Technical Information of China (English)

    Amaury G.Dumont; Sarah N.Dumont; Jonathan C.Trent

    2012-01-01

    The phosphatidylinositol-3 kinase (PI3K) pathway regulates a number of cellular processes,including cell survival,cell growth,and cell cycle progression.Consequently,this pathway is commonly deregulated in cancer.In particular,mutations in the gene PIK3CA that encodes the p110α catalytic subunit of the PI3K enzymes result in cell proliferation and resistance to apoptosis in vitro and induce breast tumors in transgenic mice.These data underscore the role of this pathway during oncogenesis.Thus,an ongoing,large-scale effort is underway to develop clinically active drugs that target elements of the PI3K pathway.However,conflicting data suggest that gain-of-function PIK3CA mutations may be associated with either a favorable or a poor clinical outcome,compared with the wild-type PIK3CA gene.In the current study,we performed a systematic review of breast cancer clinical studies.Upon evaluation of 2587 breast cancer cases from 12 independent studies,we showed that patients with tumors harboring a PIK3CA mutation have a better clinical outcome than those with a wild-type PIK3CA gene.Importantly,this improved prognosis may pertain only to patients with mutations in the kinase domain of p110α and to postmenopausal women with estrogen receptor-positive breast cancer.We propose three potential explanations for this paradoxical observation.First,PIK3CA mutations may interfere with the metastasis process or may induce senescence,which results in a better outcome for patients with mutated tumors.Secondly,we speculate that PIK3CA mutations may increase early tumor diagnosis by modification of the actin cytoskeleton in tumor cells.Lastly,we propose that PIK3CA mutations may be a favorable predictive factor for response to hormonal therapy,giving a therapeutic advantage to these patients.Ultimately,an improved understanding of the clinical impact of PIK3CA mutations is critical for the development of optimally personalized therapeutics against breast cancer and other solid tumors

  2. Apología y censura: posibles autores de las crónicas favorables a Pedro I de Castilla

    Directory of Open Access Journals (Sweden)

    González de Fauve, María Estela

    2006-06-01

    Full Text Available

    The present historiography considers that from the times of Pedro I of Castile, favorable stories to this king must have existed which were destroyed after the triumph of the Trastámara dynasty, only interested in making sure a negative picure of the ";Cruel"; king was shown. In this work we have analyzed possible authors of the chronicles called ";true"; versus Ayala's ";false";, as well as the Relación de la vida del Rey D. Pedro attributed to Gracia Dei. The research allows us to conclude that various characteristics attributed to these characters, as well as the authorship of the chronicles they are adscripted to, are part of an advertising campaign started in the sixteenth century by one branch of the Castilla lineage that looks for the reaffirmation as legitimate descendants of Pedro I.



    La historiografía actual considera que, desde la época de Pedro I de Castilla, debieron existir obras favorables a este rey que fueron destruidas, tras el triunfo de la dinastía Trastámara, interesada en que sólo se difundiera una imagen negativa del rey ";Cruel";.En este trabajo analizamos los posibles autores de esas crónicas llamadas “verdaderas” frente a la “fingida” de Ayala, así como la Relación de la vida del Rey D.Pedro... atribuida a Gracia Dei . La investigación nos permite concluir que varias de las características atribuidas a estos personajes, así como la autoría de las crónicas que se les atribuyen, forman parte de una campaña propagandística iniciada en el siglo XVI por una rama del linaje de los Castilla que busca reafirmarse como descendencia legítima de Pedro I.

  3. Delaware Basin Monitoring Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Washington Regulatory and Environmental Services; Washington TRU Solutions LLC

    2003-09-30

    The Delaware Basin Drilling Surveillance Program (DBDSP) is designed to monitor drilling activities in the vicinity of the Waste Isolation Pilot Plant (WIPP). This program is based on Environmental Protection Agency (EPA) requirements. The EPA environmental standards for the management and disposal of transuranic (TRU) radioactive waste are codified in 40 CFR Part 191 (EPA 1993). Subparts B and C of the standard address the disposal of radioactive waste. The standard requires the Department of Energy (DOE) to demonstrate the expected performance of the disposal system using a probabilistic risk assessment or performance assessment (PA). This PA must show that the expected repository performance will not release radioactive material above limits set by the EPA's standard. This assessment must include the consideration of inadvertent drilling into the repository at some future time.

  4. Delaware Basin Monitoring Annual Report

    International Nuclear Information System (INIS)

    The Delaware Basin Drilling Surveillance Program (DBDSP) is designed to monitor drilling activities in the vicinity of the Waste Isolation Pilot Plant (WIPP). This program is based on Environmental Protection Agency (EPA) requirements. The EPA environmental standards for the management and disposal of transuranic (TRU) radioactive waste are codified in 40 CFR Part 191 (EPA 1993). Subparts B and C of the standard address the disposal of radioactive waste. The standard requires the Department of Energy (DOE) to demonstrate the expected performance of the disposal system using a probabilistic risk assessment or performance assessment (PA). This PA must show that the expected repository performance will not release radioactive material above limits set by the EPA's standard. This assessment must include the consideration of inadvertent drilling into the repository at some future time.

  5. Areas where geologic conditions are more favorable for current underground mining technology in the Kaiparowits Plateau study area, southern Utah (kaisumg )

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This is a coverage that shows areas in the Kaiparowits Plateau where geologic conditions in the Calico and A-sequences are more favorable for current underground...

  6. Regional Fluid Flow and Basin Modeling in Northern Alaska

    Science.gov (United States)

    Kelley, Karen D., (Edited By)

    2007-01-01

    INTRODUCTION The foothills of the Brooks Range contain an enormous accumulation of zinc (Zn) in the form of zinc sulfide and barium (Ba) in the form of barite in Carboniferous shale, chert, and mudstone. Most of the resources and reserves of Zn occur in the Red Dog deposit and others in the Red Dog district; these resources and reserves surpass those of most deposits worldwide in terms of size and grade. In addition to zinc and lead sulfides (which contain silver, Ag) and barite, correlative strata host phosphate deposits. Furthermore, prolific hydrocarbon source rocks of Carboniferous and Triassic to Early Jurassic age generated considerable amounts of petroleum that may have contributed to the world-class petroleum resources of the North Slope. Deposits of Zn-Pb-Ag or barite as large as those in the Brooks Range are very rare on a global basis and, accordingly, multiple coincident favorable factors must be invoked to explain their origins. To improve our understanding of these factors and to contribute to more effective assessments of resources in sedimentary basins of northern Alaska and throughout the world, the Mineral Resources Program and the Energy Resources Program of the U.S. Geological Survey (USGS) initiated a project that was aimed at understanding the petroleum maturation and mineralization history of parts of the Brooks Range that were previously poorly characterized. The project, titled ?Regional Fluid Flow and Basin Modeling in Northern Alaska,? was undertaken in collaboration with industry, academia, and other government agencies. This Circular contains papers that describe the results of the recently completed project. The studies that are highlighted in these papers have led to a better understanding of the following: *The complex sedimentary facies relationships and depositional settings and the geochemistry of the sedimentary rocks that host the deposits (sections 2 and 3). *The factors responsible for formation of the barite and zinc deposits

  7. Formation mechanism and model for sand lens reservoirs in the Jiyang Sub-basin, East China

    Institute of Scientific and Technical Information of China (English)

    LI; Pilong; PANG; Xiongqi; CHEN; Dongxia; ZHANG; Shanwen

    2004-01-01

    The Bohai Bay basin comprises some very important and well documented subtle traps known in China, which have been the major exploration focus and have become a major petroleum play since the 1990s. However, recent exploration showed that the oil-bearing properties of some sand lens reservoirs may vary significantly and the accumulation mechanisms for these lithological subtle traps are not well understood. Based on statistical analysis of oil-bearing properties for 123 sand lens reservoirs in the Jiyang Sub-basin and combined with detailed anatomy of typical sand lens reservoirs and NMR experiments, it has been shown that the structural and sedimentary factors, hydrocarbon generation and expulsion conditions of the surrounding source rocks, as well as the petrophysical properties of sand lens reservoirs are the main controlling factors for the formation of sand lens reservoirs. The formation of a sand lens reservoir depends on the interaction between the hydrocarbon accumulation driving force and the resistance force. The driving force is made up of the differential capillary pressure between sandstones and sources rocks and the hydrocarbon diffusion force, and as well as the hydrocarbon expansion force. The resistance force is the friction resistance force for hydrocarbons and water to move through the pore throats of the sand lens. The sedimentary environment, source rock condition and sand reservoir properties can change from unfavorable to favorable depending on the combination of these factors. When these three factors all reach certain thresholds, the sand lens reservoirs may begin to be filled by hydrocarbons. When all of these conditions become favorable for the formation of sand lens reservoirs, the reservoir would have high oil saturation. This approach has been applied to evaluating the potential of petroleum accumulation in the sand lens reservoirs in the third member of the Neogene Shahejie Formation in the Jiyang Sub-basin.

  8. Human longevity is associated with regular sleep patterns, maintenance of slow wave sleep and favorable lipid profile

    Directory of Open Access Journals (Sweden)

    Diego Robles Mazzotti

    2014-06-01

    Full Text Available Some individuals are able to successfully reach very old ages, reflecting higher adaptation against age-associated effects. Sleep is one of the processes deeply affected by aging; however few studies evaluating sleep in long-lived individuals (aged over 85 have been reported to date. The aim of this study was to characterize the sleep patterns and biochemical profile of oldest old individuals (N=10, age 85-105 years old and compare them to young adults (N=15, age 20-30 years old and older adults (N=13, age 60-70 years old. All subjects underwent full-night polysomnography, one-week of actigraphic recording and peripheral blood collection. Sleep electroencephalogram spectral analysis was also performed. The oldest old individuals showed lower sleep efficiency and REM sleep when compared to the older adults, while stage N3 percentage and delta power were similar across the groups. Oldest old individuals maintained strictly regular sleep-wake schedules and also presented higher HDL-cholesterol and lower triglyceride levels than older adults. The present study revealed novel data regarding specific sleep patterns and maintenance of slow wave sleep in the oldest old group. Taken together with the favorable lipid profile, these results contribute with evidence to the importance of sleep and lipid metabolism regulation in the maintenance of longevity in humans.

  9. A new scalar resonance at 750 GeV: Towards a proof of concept in favor of strongly interacting theories

    CERN Document Server

    Son, Minho

    2015-01-01

    We interpret the recently observed excess in diphoton invariant mass as a new spin-0 resonant particle. On the theoretical ground, an interesting question is whether this new scalar resonance belongs to a strongly coupled sector or a well-defined weakly coupled theory. A possible UV-completion that has been widely considered in literature is based on the existence of new vector-like fermions whose loop contributions---Yukawa-coupled to the new resonance---explain the observed signal rate. The large total width preliminarily suggested by data seems to favor a large Yukawa coupling, at the border of a healthy perturbative definition. This potential problem can be fixed by introducing multiple vector-like fermions or large electric charges, bringing back the theory to a weakly coupled regime. However, this solution risks to be only a low-energy mirage: Large multiplicity or electric charge can dangerously reintroduce the strong regime by modifying the renormalization group running of the dimensionless couplings....

  10. Impairment of ATP hydrolysis decreases adenosine A1 receptor tonus favoring cholinergic nerve hyperactivity in the obstructed human urinary bladder.

    Science.gov (United States)

    Silva-Ramos, M; Silva, I; Faria, M; Magalhães-Cardoso, M T; Correia, J; Ferreirinha, F; Correia-de-Sá, P

    2015-12-01

    This study was designed to investigate whether reduced adenosine formation linked to deficits in extracellular ATP hydrolysis by NTPDases contributes to detrusor neuromodulatory changes associated with bladder outlet obstruction in men with benign prostatic hyperplasia (BPH). The kinetics of ATP catabolism and adenosine formation as well as the role of P1 receptor agonists on muscle tension and nerve-evoked [(3)H]ACh release were evaluated in mucosal-denuded detrusor strips from BPH patients (n = 31) and control organ donors (n = 23). The neurogenic release of ATP and [(3)H]ACh was higher (P bladders. Relaxation of detrusor contractions induced by acetylcholine required 30-fold higher concentrations of adenosine. Despite VAChT-positive cholinergic nerves exhibiting higher A(1) immunoreactivity in BPH bladders, the endogenous adenosine tonus revealed by adenosine deaminase is missing. Restoration of A1 inhibition was achieved by favoring (1) ATP hydrolysis with apyrase (2 U mL(-1)) or (2) extracellular adenosine accumulation with dipyridamole or EHNA, as these drugs inhibit adenosine uptake and deamination, respectively. In conclusion, reduced ATP hydrolysis leads to deficient adenosine formation and A(1) receptor-mediated inhibition of cholinergic nerve activity in the obstructed human bladder. Thus, we propose that pharmacological manipulation of endogenous adenosine levels and/or A(1) receptor activation might be useful to control bladder overactivity in BPH patients. PMID:26521170

  11. Use of RegCM gridded dataset for thunderstorm favorable conditions analysis over Poland—climatological approach

    Science.gov (United States)

    Walawender, Ewelina; Kielar, Rafał; Ustrnul, Zbigniew

    2015-09-01

    The paper analyzes equivalent data for a low density meteorological station network (spatially discontinuous data) and poor temporal homogeneity of thunderstorm observational data. Due to that, a Regional Climate Model (RegCM) dataset was tested. The Most Unstable Convective Available Potential Energy index value (MUCAPE) above the 200 J kg-1 threshold was selected as a predictor describing favorable conditions for the occurrence of thunderstorms. The quality of the dataset was examined through a comparison between model results and soundings from several aerological stations in Central Europe. Good, statistically significant (0.05 significance level) results were obtained through correlation analysis; the value of Pearson's correlation coefficient was above 0.8 in every single case. Then, using methods associated with gridded climatology, data series for 44 weather stations were derived and an analysis of correlation between RegCM modeled data and in situ thunderstorm observations was conducted with coefficients in the range of 0.75-0.90. The possibility of employing the dataset in thunderstorm climatology analysis was checked via a few examples by mapping monthly, seasonal, and annual means. Moreover, long-term variability and trend analysis along with modeled MUCAPE data were tested. As a result, the RegCM modeled MUCAPE gridded dataset was proposed as an easily available, suitable, and valuable predictor for thunderstorm climatology analysis and mapping. Finally, some limitations are discussed and recommendations for further improvements are given.

  12. Bilayer porous scaffold based on poly-(ɛ-caprolactone) nanofibrous membrane and gelatin sponge for favoring cell proliferation

    Science.gov (United States)

    Zhou, Zhihua; Zhou, Yang; Chen, Yiwang; Nie, Huarong; Wang, Yang; Li, Fan; Zheng, Yan

    2011-12-01

    Electrospun poly-(ɛ-caprolactone) (PCL) nanofibers has been widely used in the medical prosthesis. However, poor hydrophilicity and the lack of natural recognition sites for covalent cell-recognition signal molecules to promote cell attachment have limited its utility as tissue scaffolds. In this study, Bilayer porous scaffolds based on PCL electrospun membranes and gelatin (GE) sponges were fabricated through soft hydrolysis of PCL electrospun followed by grafting gelatin onto the fiber surface, through crosslinking and freeze drying treatment of additional gelatin coat and grafted gelatin surface. GE sponges were stably anchored on PCL membrane surface with the aid of grafted GE molecules. The morphologies of bilayer porous scaffolds were observed through SEM. The contact angle of the scaffolds was 0°, the mechanical properties of scaffolds were measured by tensile test, Young's moduli of PCL scaffolds before and after hydrolysis are 66-77.3 MPa and 62.3-75.4 MPa, respectively. Thus, the bilayer porous scaffolds showed excellent hydrophilic surface and desirable mechanical strength due to the soft hydrolysis and GE coat. The cell culture results showed that the adipose derived mesenchymal stem cells did more favor to adhere and grow on the bilayer porous scaffolds than on PCL electrospun membranes. The better cell affinity of the final bilayer scaffolds not only attributed to the surface chemistry but also the introduction of bilayer porous structure.

  13. Bilayer porous scaffold based on poly-(ε-caprolactone) nanofibrous membrane and gelatin sponge for favoring cell proliferation

    International Nuclear Information System (INIS)

    Electrospun poly-(ε-caprolactone) (PCL) nanofibers has been widely used in the medical prosthesis. However, poor hydrophilicity and the lack of natural recognition sites for covalent cell-recognition signal molecules to promote cell attachment have limited its utility as tissue scaffolds. In this study, Bilayer porous scaffolds based on PCL electrospun membranes and gelatin (GE) sponges were fabricated through soft hydrolysis of PCL electrospun followed by grafting gelatin onto the fiber surface, through crosslinking and freeze drying treatment of additional gelatin coat and grafted gelatin surface. GE sponges were stably anchored on PCL membrane surface with the aid of grafted GE molecules. The morphologies of bilayer porous scaffolds were observed through SEM. The contact angle of the scaffolds was 0°, the mechanical properties of scaffolds were measured by tensile test, Young's moduli of PCL scaffolds before and after hydrolysis are 66-77.3 MPa and 62.3-75.4 MPa, respectively. Thus, the bilayer porous scaffolds showed excellent hydrophilic surface and desirable mechanical strength due to the soft hydrolysis and GE coat. The cell culture results showed that the adipose derived mesenchymal stem cells did more favor to adhere and grow on the bilayer porous scaffolds than on PCL electrospun membranes. The better cell affinity of the final bilayer scaffolds not only attributed to the surface chemistry but also the introduction of bilayer porous structure.

  14. JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis.

    Science.gov (United States)

    Grisouard, Jean; Li, Sai; Kubovcakova, Lucia; Rao, Tata Nageswara; Meyer, Sara C; Lundberg, Pontus; Hao-Shen, Hui; Romanet, Vincent; Murakami, Masato; Radimerski, Thomas; Dirnhofer, Stephan; Skoda, Radek C

    2016-08-11

    Mutations in JAK2 exon 12 are frequently found in patients with polycythemia vera (PV) that do not carry a JAK2-V617F mutation. The majority of these patients display isolated erythrocytosis. We generated a mouse model that expresses JAK2-N542-E543del, the most frequent JAK2 exon 12 mutation found in PV patients. Mice expressing the human JAK2-N542-E543del (Ex12) showed a strong increase in red blood cell parameters but normal neutrophil and platelet counts, and reduced overall survival. Erythropoiesis was increased in the bone marrow and spleen, with normal megakaryopoiesis and absence of myelofibrosis in histopathology. Erythroid progenitors and precursors were increased in hematopoietic tissues, but the numbers of megakaryocytic precursors were unchanged. Phosphorylation Stat3 and Erk1/2 proteins were increased, and a trend toward increased phospho-Stat5 and phospho-Stat1 was noted. However, Stat1 knock out in Ex12 mice induced no changes in platelet or red cell parameters, indicating that Stat1 does not play a central role in mediating the effects of Ex12 signaling on megakaryopoiesis or erythropoiesis. Ex12 mice showed decreased expression of hepcidin and increased expression of transferrin receptor-1 and erythroferrone, suggesting that the strong erythroid phenotype in Ex12 mutant mice is favored by changes in iron metabolism that optimize iron availability to allow maximal production of red cells. PMID:27288519

  15. The HII Galaxy Hubble Diagram Strongly Favors $R_{\\rm h}=ct$ over $\\Lambda$CDM

    CERN Document Server

    Wei, Jun-Jie; Melia, Fulvio

    2016-01-01

    We continue to build support for the proposal to use HII galaxies (HIIGx) and giant extragalactic HII regions (GEHR) as standard candles to construct the Hubble diagram at redshifts beyond the current reach of Type Ia supernovae. Using a sample of 25 high-redshift HIIGx, 107 local HIIGx, and 24 GEHR, we confirm that the correlation between the emission-line luminosity and ionized-gas velocity dispersion is a viable luminosity indicator, and use it to test and compare the standard model $\\Lambda$CDM and the $R_{\\rm h}=ct$ Universe by optimizing the parameters in each cosmology using a maximization of the likelihood function. For the flat $\\Lambda$CDM model, the best fit is obtained with $\\Omega_{\\rm m}= 0.40_{-0.09}^{+0.09}$. However, statistical tools, such as the Akaike (AIC), Kullback (KIC) and Bayes (BIC) Information Criteria favor $R_{\\rm h}=ct$ over the standard model with a likelihood of $\\approx 94.8\\%-98.8\\%$ versus only $\\approx 1.2\\%-5.2\\%$. For $w$CDM (the version of $\\Lambda$CDM with a dark-energy...

  16. Birth Weight, Birth Length, and Gestational Age as Indicators of Favorable Fetal Growth Conditions in a US Sample

    Science.gov (United States)

    Bollen, Kenneth A.

    2016-01-01

    The “fetal origins” hypothesis suggests that fetal conditions not only affect birth characteristics such as birth weight and gestational age, but also have lifelong health implications. Despite widespread interest in this hypothesis, few methodological advances have been proposed to improve the measurement and modeling of fetal conditions. A Statistics in Medicine paper by Bollen, Noble, and Adair examined favorable fetal growth conditions (FFGC) as a latent variable. Their study of Filipino children from Cebu provided evidence consistent with treating FFGC as a latent variable that largely mediates the effects of mother’s characteristics on birth weight, birth length, and gestational age. This innovative method may have widespread utility, but only if the model applies equally well across diverse settings. Our study assesses whether the FFGC model of Cebu replicates and generalizes to a very different population of children from North Carolina (N = 705) and Pennsylvania (N = 494). Using a series of structural equation models, we find that key features of the Cebu analysis replicate and generalize while we also highlight differences between these studies. Our results support treating fetal conditions as a latent variable when researchers test the fetal origins hypothesis. In addition to contributing to the substantive literature on measuring fetal conditions, we also discuss the meaning and challenges involved in replicating prior research. PMID:27097023

  17. Bilayer porous scaffold based on poly-({epsilon}-caprolactone) nanofibrous membrane and gelatin sponge for favoring cell proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Zhihua; Zhou Yang [Department of Chemistry, Nanchang University, 999 Xuefu Avenue, Nanchang 330031 (China); Chen Yiwang, E-mail: ywchen@ncu.edu.cn [Department of Chemistry, Nanchang University, 999 Xuefu Avenue, Nanchang 330031 (China); Institute of Polymers, Nanchang University, 999 Xuefu Avenue, Nanchang 330031 (China); Nie Huarong, E-mail: niehr@iccas.ac.cn [Institute of Polymers, Nanchang University, 999 Xuefu Avenue, Nanchang 330031 (China); Wang Yang [First Affiliated Hospital, Nanchang University, 17 Yongwaizheng Road, Nanchang 330006 (China); Li Fan; Zheng Yan [Institute of Polymers, Nanchang University, 999 Xuefu Avenue, Nanchang 330031 (China)

    2011-12-15

    Electrospun poly-({epsilon}-caprolactone) (PCL) nanofibers has been widely used in the medical prosthesis. However, poor hydrophilicity and the lack of natural recognition sites for covalent cell-recognition signal molecules to promote cell attachment have limited its utility as tissue scaffolds. In this study, Bilayer porous scaffolds based on PCL electrospun membranes and gelatin (GE) sponges were fabricated through soft hydrolysis of PCL electrospun followed by grafting gelatin onto the fiber surface, through crosslinking and freeze drying treatment of additional gelatin coat and grafted gelatin surface. GE sponges were stably anchored on PCL membrane surface with the aid of grafted GE molecules. The morphologies of bilayer porous scaffolds were observed through SEM. The contact angle of the scaffolds was 0 Degree-Sign , the mechanical properties of scaffolds were measured by tensile test, Young's moduli of PCL scaffolds before and after hydrolysis are 66-77.3 MPa and 62.3-75.4 MPa, respectively. Thus, the bilayer porous scaffolds showed excellent hydrophilic surface and desirable mechanical strength due to the soft hydrolysis and GE coat. The cell culture results showed that the adipose derived mesenchymal stem cells did more favor to adhere and grow on the bilayer porous scaffolds than on PCL electrospun membranes. The better cell affinity of the final bilayer scaffolds not only attributed to the surface chemistry but also the introduction of bilayer porous structure.

  18. N4-methylation of cytosine drastically favors the formation of (6-4) photoproducts in a TCG context.

    Science.gov (United States)

    Douki, Thierry; Meador, Jarah A; Bérard, Izabel; Wack, Aude

    2015-01-01

    Methylation of cytosine is a common biological process both in prokaryotic and eukaryotic cells. In addition to 5-methylcytosine (5mC), some bacterial species contain in their genome N(4) -methylcytosine (N4mC). Methylation at C5 has been shown to enhance the formation of pyrimidine dimeric photoproducts but nothing is known of the effect of N4 methylation on UV-induced DNA damage. In the present work, we compared the yield and the nature of bipyrimidine photoproducts induced in a series of trinucleotides exhibiting a TXG sequence where X is either T, C, 5mC or N4mC. HPLC associated to tandem mass spectrometry was used to quantify cyclobutane pyrimidine dimers (CPD), (6-4) photoproducts (64PP) and their Dewar valence isomer. Methylation at position N4 was found to drastically increase the reactivity of C upon exposure to both UVC and UVB and to favor the formation of 64PP. In contrast methylation at C5 increased the yield of CPD at the expense of 64PP. In addition, enhancement of photoreactivity by C5 methylation was much higher in the UVB than in the UVC range. These results show the drastic effect of the methylation site on the photochemistry of cytosine. PMID:25319211

  19. Groundwater Mounding Beneath Stormwater Infiltration Basins

    Science.gov (United States)

    Nimmer, M.; Thompson, A. M.; Misra, D.

    2007-12-01

    An accurate understanding of groundwater mound formation is important in the proper design of stormwater infiltration basins since these basins are often required to recharge a portion of pre-development infiltration volume. Mound formation due to localized recharge may reduce the infiltration rate of the basin and the ability of the soil to filter pollutants. The goal of this research was to understand groundwater mounding and the potential for contaminant transport resulting from recharge beneath stormwater infiltration basins. A 0.10 ha infiltration basin serving a 9.4 ha residential subdivision in Oconomowoc, Wisconsin was used in this study. Subsurface conditions included sand and gravel material and a groundwater table at 2.3 m below grade. Three storm events, 4.9 cm, 2.8 cm, and 4.3 cm, between August 2006 and April 2007 were modeled using the two-dimensional numerical model HYDRUS. The calibrated model was used to evaluate hypothetical basin operation scenarios for various basin sizes, soil types, ponding depths, and water table depths. The groundwater mound intersected the basin floor in most scenarios with loamy sand and sandy loam soils, an unsaturated thickness of 1.52 m, and a ponding depth of 0.61 m. No groundwater table response was observed with ponding depths less than 0.31 m with an unsaturated zone thickness of 6.09 m. The mound height was most sensitive to hydraulic conductivity and unsaturated zone thickness. A 7.6 cm sediment layer delayed the time to reach maximum mound height, but had a minimal effect on the magnitude of the mound. Mound heights increased as infiltration basin size increased.

  20. "Grupo" de artesanato: espaço favorável à promoção da saúde mental "Grupo" de artesanía: espacio favorable a la promoción de la salud mental Artisan group: a favorable space promoting mental health

    Directory of Open Access Journals (Sweden)

    Márcia Glaciela da Cruz Scardoelli

    2011-06-01

    Full Text Available Estudo descritivo de abordagem qualitativa, realizado em um grupo de artesanato de uma Unidade Básica de Saúde do município de Maringá - PR, no período de março a agosto de 2009. Objetivou-se compreender os motivos de inserção de mulheres no grupo de artesanato. Para coleta de dados utilizaram-se a observação participante e entrevista aberta. Os sujeitos do estudo foram 11 mulheres. Os dados foram analisados segundo a técnica de análise de conteúdo, de onde emergiram três categorias: Propiciando a promoção da saúde mental; Encontrando um espaço que promove a fala, a escuta e a partilha e; Buscando um espaço de ensino/aprendizado. Observamos que participar do grupo vem contribuindo para melhoria da qualidade de vida destas mulheres que se encontravam em situação de sofrimento emocional, oferecendo condições favoráveis ao desenvolvimento do ponto de vista psicossocial.Estudio descriptivo de abordaje cualitativo, realizado en un grupo de artesanía de una Unidad Básica de Salud del municipio de Maringá - PR, durante el periodo de marzo a agosto de 2009. El objetivo fue comprender los motivos de inserción de mujeres en el grupo de artesanía. Para la colecta de datos, se utilizó la observación participativa y una entrevista abierta realizada a domicilio. Los sujetos del estudio fueron 11 mujeres. Los datos fueron analizados según la técnica de análisis de contenido, de donde emergieron tres categorías: Proporcionar la promoción de la salud mental; Búsqueda de un espacio para hablar, escuchar y compartir y; Búsqueda de un espacio de educación/aprendizado. Observamos que la participación del grupo viene contribuyendo para la mejoría de la calidad de vida de estas mujeres que se encontraban en situación de sufrimiento emocional, ofreciendo condiciones favorables para su desarrollo psicosocial.Current paper deals with a descriptive study based on a qualitative approach with regard to an artisan group of a Health

  1. Geohydrology surrounding a potential high level nuclear waste repository in the Palo Duro Basin, Texas

    International Nuclear Information System (INIS)

    The Palo Duro Basin of the Texas Panhandle is being investigated as a potential high level nuclear waste repository site. As groundwater is the most likely mechanism for radionuclide movement, it is desirable to locate a repository in a hydrologic regime which is favorable for waste isolation and containment. The Palo Duro Basin consists of deep brine aquifers of low regional permeability underlying a thick Permian age evaporite section. The overlying Permian age evaporites are the Dockum and Ogallala fresh water aquifiers. Observed potentiometric data in the principal aquifers indicate a potential for downward flow from the surficial aquifiers to the deep brine aquifers. Groundwater movement in these deep aquifers is very slow. Modeling efforts indicate flow times of hundreds of thousands to over a million years for groundwater to reach the basin margins. Investigative methods have included drill-stem testing similar to oil field methodology, modified drill-stem testing with tools developed for low-permeability formations and long term production tests similar to conventional water well pumping tests. Testing has generally indicated permeability of .1-10 millidarcies in the water transmitting units

  2. Tectonic geomorphology of large normal faults bounding the Cuzco rift basin within the southern Peruvian Andes

    Science.gov (United States)

    Byers, C.; Mann, P.

    2015-12-01

    The Cuzco basin forms a 80-wide, relatively flat valley within the High Andes of southern Peru. This larger basin includes the regional capital of Cuzco and the Urubamba Valley, or "Sacred Valley of the Incas" favored by the Incas for its mild climate and broader expanses of less rugged and arable land. The valley is bounded on its northern edge by a 100-km-long and 10-km-wide zone of down-to-the-south systems of normal faults that separate the lower area of the down-dropped plateau of central Peru and the more elevated area of the Eastern Cordillera foldbelt that overthrusts the Amazon lowlands to the east. Previous workers have shown that the normal faults are dipslip with up to 600 m of measured displacements, reflect north-south extension, and have Holocene displacments with some linked to destructive, historical earthquakes. We have constructed topographic and structural cross sections across the entire area to demonstrate the normal fault on a the plateau peneplain. The footwall of the Eastern Cordillera, capped by snowcapped peaks in excess of 6 km, tilts a peneplain surface northward while the hanging wall of the Cuzco basin is radially arched. Erosion is accelerated along the trend of the normal fault zone. As the normal fault zone changes its strike from east-west to more more northwest-southeast, normal displacement decreases and is replaced by a left-lateral strike-slip component.

  3. Tertiary Sea Level Changes and Sequence Stratigraphic Framework in East China Sea Shelf Basin

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    The East China Sea shelf basin is a key area for setting up the sea level changes of Cenozoic in the West Pacific. Based upon the characteristics of seismic reflection, the analysis of sequence stratigraphy and depositional system, the high-resolution chronostratigraphic framework has been set up by using the data of micropaleontologic biozone fossils. The relative sea level change curve has been set up by combining analysis of paleoecology, genetic facies, specific sedimentary structures and on-lap recognized from the seismic profiles with study of geochemical characteristics. There are 4 2nd-order basin cycles showing the long-term sea level changes, and 22 3rd-order cycles showing short-term ones with relative changing ranges of 0-150 m. Transgression and regression showing long-term sea level changes bear asymmetric feature, which indicates that the speed of transgression is faster than that of regression. There are a lot of differences when compared with Haq's curve. The sequence stratigraphic framework has also been set up and 3 tectonic sequences, 7 supersequences and 19 sequences have been subdivided for Tertiary in the East China Sea shelf basin. On the basis of detailed analysis of genetic facies and log facies, 9 sedimentary systems, 20 depositional assemblages and many genetic facies have also been recognized and investigated. Based on the studies mentioned above, the favorable source and reservoir facies of gas and petroleum are indicated.

  4. ODONATE COMMUNITIES (ODONATA:INSECTA) IN A TROPICAL RIVER BASIN,MALAYSIA

    Institute of Scientific and Technical Information of China (English)

    Che Salmah M R; Abu Hassan A; Ameilia Z S

    2004-01-01

    Odonata larvae were sampled from 16 tributaries of Kerian River in the Kerian River Basin (KRB) usinga kick sampling technique from September 1998 to May 1999 encompassing both rainy and dry seasons. The distribu-tion of odonate genera was significantly different ( F15,46,= 3.99) among rivers in both seasons ( F15,16 = 4.70) at P =0.05. However, no seasonal influence was detected. Protoneuridae and Libellulidae were the most dominant families inthis basin. Other families Gomphidae, Coenagrionidae, Macromiidae, Chlorocyphidae and Calopterygidae, were com-mon but Aeshnidae and Eupheidae were rare. Several common species, Prodasineura autumnalis, Brachythemis con-taminata, Macromia gerstaeckeri , Paragomphus , Orthetrum brunneum , Rhinocypha quadrimaculata and Coperamarginipes were identified. The calculated values of biological indices ( H', D, E, R 1 and R2) showed that the drag-onfly fauna in this river basin was slightly poor. Varied physico - chemical parameters of the river possibly as a result ofhuman activities in surrounding areas were found to influence the distribution of the dragonfly larvae in the KRB. Thisstudy showed that the KRB provided favorable habitats for Protoneuridae and 1Libellulidae. Two most dominantspecies Prodasineura autumnalis and Brachythemis contaminata were obviously favoured slightly acidic water of theKerian river tributaries.

  5. Radionuclides in the Great Lakes basin.

    OpenAIRE

    Ahier, B A; Tracy, B L

    1995-01-01

    The Great Lakes basin is of radiologic interest due to the large population within its boundaries that may be exposed to various sources of ionizing radiation. Specific radionuclides of interest in the basin arising from natural and artificial sources include 3H, 14C, 90Sr, 129I, 131I, 137Cs, 222Rn, 226Ra, 235U, 238U, 239Pu, and 241Am. The greatest contribution to total radiation exposure is the natural background radiation that provides an average dose of about 2.6 mSv/year to all basin resi...

  6. K Basins isolation barriers summary report

    Energy Technology Data Exchange (ETDEWEB)

    Strickland, G.C., Westinghouse Hanford

    1996-07-31

    The 105-K East and 105-K West fuel storage basins (105-K Basins) were designed and constructed in the early 1950`s for interim storage of irradiated fuel following its discharge from the reactors. The 105-K- East and 105-K West reactor buildings were constructed first, and the associated storage basins were added about a year later. The construction joint between each reactor building structure and the basin structure included a flexible membrane waterstop to prevent leakage. Water in the storage basins provided both radiation shielding and cooling to remove decay heat from stored fuel until its transfer to the Plutonium Uranium Extraction (PUREX) Facility for chemical processing. The 105-K West Reactor was permanently shut down in February 1970; the 105-K East Reactor was permanently shut down in February 1971. Except for a few loose pieces, fuel stored in the basins at that time was shipped to the PUREX Facility for processing. The basins were then left idle but were kept filled with water. The PUREX Facility was shut down and placed on wet standby in 1972 while N Reactor continued to operate. When the N Reactor fuel storage basin began to approach storage capacity, the decision was made to modify the fuel storage basins at 105-K East and 105-K West to provide additional storage capacity. Both basins were subsequently modified (105-K East in 1975 and 105-K West in 1981) to provide for the interim handling and storage of irradiated N Reactor fuel. The PUREX Facility was restarted in November 1983 to provide 1698 additional weapons-grade plutonium for the United States defense mission. The facility was shut down and deactivated in December 1992 when the U.S. Department of Energy (DOE) determined that the plant was no longer needed to support weapons-grade plutonium production. When the PUREX Facility was shut down, approximately 2.1 x 1 06 kg (2,100 metric tons) of irradiated fuel aged 7 to 23 years was left in storage in the 105-K Basins pending a decision on

  7. China's Qaidam Basin Sensitive to Global Warming

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Chinese meteorologists recently pointed out that the temperatures in northwest China's resource-rich Qaidam Basin are rising faster than the rest of the country as a result of climate change.The rapid rise in temperatures is likely to increase the long-term frequency of droughts and farming pests in the basin to the northeast of the Qinghai-Tibet Plateau.Qaidam Basin covers 250,000 km2 in Qinghai Province and is known as resource-rich with salt lakes,petroleum,natural gas and other abundant mineral resources.

  8. Basins of Attraction for Chimera States

    DEFF Research Database (Denmark)

    Martens, Erik Andreas; Panaggio, Mark; Abrams, Daniel

    2016-01-01

    Chimera states---curious symmetry-broken states in systems of identical coupled oscillators---typically occur only for certain initial conditions. Here we analyze their basins of attraction in a simple system comprised of two populations. Using perturbative analysis and numerical simulation we...... evaluate asymptotic states and associated destination maps, and demonstrate that basins form a complex twisting structure in phase space. Understanding the basins' precise nature may help in the development of control methods to switch between chimera patterns, with possible technological and neural system...

  9. The relationship between dolomitization and organic matter occurrence in Lower Paleozoic carbonate in the Ordos Basin

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Based on observations on the core and surface sections of Lower Paleozoic carbonate in the Ordos Basin, petrography research and measurements of TOC, TOS , Ro, XRD, and comparative study with dolomite in modern Coorong Lake, it has been revealed that: (i)dolomitization may occur in micrite limestone, gypsum-halite and argillaceous sandstone, and it can be divided into three types: sedimentary penecontemporaneous-early diagenesis, late diagenesis of deep burial and catagenesis of uplift period. However, the crystal cell of the second type less than 35 μ m in size is most closely associated with gas pool; (ii) the highest content of organic matter (OM) is produced in samples from the argillic dolomite which may be formed by argillaceous fluid through gypsum-halite; (iii) in the evolution process from penecontemporaneous dolomite into stoichiometric dolomite, the crystal order of dolomite and the porosity of its host rock tend to increase, which is favorable to the formation of an available migration network. When the power of the fluid is high enough, the network is mainly favorable to the migration and transport of heat, but when the power of the fluid goes down, the network system is favorable, due to its large space, to OM deposition in it.

  10. Waste storage potential of Triassic basins in southeast United States

    Energy Technology Data Exchange (ETDEWEB)

    Weaver, C.E.

    1976-07-01

    Triassic basins, elongated deep basins filled with sediments, extend from Nova Scotia to Florida. The geology of the basins is discussed for each state. Their potential for liquid waste storage is assessed. Seismic risk is among the factors evaluated. It is recommended that the shallow Triassic Florence basin in northeast South Carolina be studied. 10 fig. (DLC)

  11. Western Gas Sands Project. Quarterly Basin Activities Report

    Energy Technology Data Exchange (ETDEWEB)

    Atkinson, C H

    1979-01-31

    This report is a summation of 3 months' drilling and testing activities in the four primary WGSP study areas: Greater Green River Basin, Northern Great Plains Province, Piceance Basin, and Uinta Basin. The monitoring of basin activities is part of resource assessment. (DLC)

  12. K Basins Groundwater Monitoring Task, K Basins Closure Project: Report for April, May, and June 2007

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, Robert E.

    2007-08-08

    This report provides information on groundwater monitoring near the K Basins during April, May, and June 2007. Conditions remained similar to those reported in the previous quarter’s report, with no evidence in monitoring results to suggest groundwater impact from current loss of shielding water from either basin to the ground. During the current quarter, the first results from two new wells installed between KE Basin and the river became available. Groundwater conditions at each new well are reasonably consistent with adjacent wells and expectations, with the exception of anomalously high chromium concentrations at one of the new wells. The K Basins monitoring network will be modified for FY 2008 to take advantage of new wells recently installed near KW Basin as part of a pump-and-treat system for chromium contamination, and also the new wells recently installed between the KE Basin and the river, which augment long-term monitoring capability in that area.

  13. Integrated Water Resources Management Improving Langat Basin Ecosystem Health

    Directory of Open Access Journals (Sweden)

    Mazlin B. Mokhtar

    2008-01-01

    Full Text Available The ecosystem provides us with all the goods and services that form the base of our economic, social cultural and spiritual life. Good scientific information will be required for managing the environment by using the Ecosystem approach. The groundwater is considered as a possible supplementary of alternative water source, and some factories already started shifting their water source from surface water to groundwater. Uncontrolled use of groundwater, however, may induce serious environmental problems, e.g., land subsidence, saltwater intrusion to the aquifer. The establishment of a balanced multi-sector and integrated groundwater resources and environmental management plan is deemed urgent to attain a sustainable groundwater resources use and to maintain a favorable groundwater quality in the Langat Basin. To achieve sustainable lifestyle in large scale ecosystem requires integrated and holistic approaches from all stakeholders. Through Aquifer Storage Recovery (ASR it was determined a revolutionized water resources management, providing a sustainable supply while minimizing the environmental impact of surface storage. By using underground geologic formations to store water, by integrated water resources management advisory system (IWRMAS aquifer recharge can now easily applied to obviate water resource and environmental problems, including seasonal shortages, emergency storage, ground subsidence and saline intrusion.

  14. Multi-National River Basin Cooperation and Management Case Study: Senegal River Basin

    OpenAIRE

    Ayaa, Patricia

    2012-01-01

    With increasing populations, urbanization and thus increasing demand for water, conflict on International River basins has been increasing over the years which has necessitated formation of International River frameworks to devise means of cooperation among the countries sharing the river basins. The main modes of cooperation in international river basins include allocating the waters of the river to the sharing countries such that each country manages its own water resources, or treating the...

  15. Modelling depositional shifts between sedimentary basins: Sediment pathways in Paratethys basins during the Messinian Salinity Crisis

    OpenAIRE

    J. Bartol; L. Matenco; D. Garcia-Castellanos; K. Leever

    2012-01-01

    The evolution of sedimentary basins separated by uplifted topographic barriers is characterised by gradual regressive deposition until one of the basins is filled and its sedimentation bypasses to the adjacent basin, defining a depositional shift. One of the critical parameters controlling these depositional shifts is sea level variation, its drop potentially triggering a depositional shift by cancelling the available accommodation space. Conversely, a sea level rise can create new accommodat...

  16. Structural Architecture and Evolution of Kumkuli Basin, North Tibet

    Institute of Scientific and Technical Information of China (English)

    He Bizhu; Xu Zhiqin; Jiao Cunli; Cui Junwen; Wang Shenglang; Wang Gonghuai; Li Zhaoyang; Qiu Zhuli

    2009-01-01

    Utilizing the new data of gravity, magnetic, and magnetotelluric survey, we analyzed the characteristics of the three geophysical attribute (gravity, magnetic, and resistivity) interfaces and the deep architecture and structure of Kumkuli basin. The research results can provide basic data for early basin structural study. From coupled basin and mountain system, analysis of the structure, and evolution of Knmknli basin, we found that there was zoning from north to south and from west to east. Kumkuli basin has three structural architecture layers including metamorphic crystallization basement, fold basement and sedimentary cover. Knmkuli basin can be divided into three structural units, two depressions, and one uplift. Structural evolution of the Kumkuli basin can be divided into five evolution stages, including Kumkuli microcontinent formed in Sinian-Ordovician, suture around Kumkuli basin formed in Eopaleozoic, retroarc foreland basin formed in Neopaleozoic, rejuvenated foreland hasin developed in Mesozoic, and strike slip and compression basin developed in Cenozoic.

  17. Urethral stricture vaporization with the KTP laser provides evidence for a favorable impact of laser surgery on wound healing

    Science.gov (United States)

    Schmidlin, Franz R.; Venzi, Giordano; Jichlinski, Patrice; Oswald, Michael; Delacretaz, Guy P.; Gabbiani, Giulio; Leisinger, Hans-Juerg; Graber, Peter

    1997-12-01

    The objective of this study was to evaluate and compare the safety and efficacy of the KTP 532 laser to direct vision internal urethrotomy (DVIU) in the management of urethral strictures. A total of 32 patients were randomized prospectively in this study, 14 DVIU and 18 KTP 532 laser. Patients were evaluated postoperatively with flowmetry and in the case of recurrence with cystourethrography at 3, 12, 24 weeks. With the KTP 532 laser complete symptomatic and uredynamic success was achieved in 15 (83%) patients at 12 and 24 weeks. Success rate was lower in the DVIU group with 9 (64%) patients at 12 weeks and 8 (57%) patients at 24 weeks. Mean preoperative peak-flow was improved from 6 cc/s to 20 cc/s at 3, 12 and 24 weeks with the KTP laser. With DVIU mean preoperative peak-flow was improved from 5.5 cc/s to 20 cc/s at 3 weeks followed by a steady decrease to 13 cc/s at 12 weeks and to 12 cc/s 24 weeks. No complication was observed in either group of patients. Our results confirm that stricture vaporization with the KTP 532 laser is a safe and efficient procedure. The better results after laser surgery make it also a valuable alternative in the endoscopic treatment of urethral strictures. These findings suggest a favorable influence of laser surgery on wound healing with less wound contraction and scarring. The lack of contraction of laser wounds might be related to the absence and the lack of organization of myofibroblasts in laser induced lesions.

  18. Favorable Alteration of Tumor Microenvironment by Immunomodulatory Cytokines for Efficient T-Cell Therapy in Solid Tumors

    Science.gov (United States)

    Tähtinen, Siri; Kaikkonen, Saija; Merisalo-Soikkeli, Maiju; Grönberg-Vähä-Koskela, Susanna; Kanerva, Anna; Parviainen, Suvi; Vähä-Koskela, Markus; Hemminki, Akseli

    2015-01-01

    Unfavorable ratios between the number and activation status of effector and suppressor immune cells infiltrating the tumor contribute to resistance of solid tumors to T-cell based therapies. Here, we studied the capacity of FDA and EMA approved recombinant cytokines to manipulate this balance in favor of efficient anti-tumor responses in B16.OVA melanoma bearing C57BL/6 mice. Intratumoral administration of IFN-α2, IFN-γ, TNF-α, and IL-2 significantly enhanced the anti-tumor effect of ovalbumin-specific CD8+ T-cell (OT-I) therapy, whereas GM-CSF increased tumor growth in association with an increase in immunosuppressive cell populations. None of the cytokines augmented tumor trafficking of OT-I cells significantly, but injections of IFN-α2, IFN-γ and IL-2 increased intratumoral cytokine secretion and recruitment of endogenous immune cells capable of stimulating T-cells, such as natural killer and maturated CD11c+ antigen-presenting cells. Moreover, IFN-α2 and IL-2 increased the levels of activated tumor-infiltrating CD8+ T-cells concomitant with reduction in the CD8+ T-cell expression of anergy markers CTLA-4 and PD-1. In conclusion, intratumoral administration of IFN-α2, IFN-γ and IL-2 can lead to immune sensitization of the established tumor, whereas GM-CSF may contribute to tumor-associated immunosuppression. The results described here provide rationale for including local administration of immunostimulatory cytokines into T-cell therapy regimens. One appealing embodiment of this would be vectored delivery which could be advantageous over direct injection of recombinant molecules with regard to efficacy, cost, persistence and convenience. PMID:26107883

  19. External beam accelerated partial breast irradiation (EB-APBI yields favorable outcomes in patients with prior breast augmentation

    Directory of Open Access Journals (Sweden)

    Rachel Yi-Feng Lei

    2014-06-01

    Full Text Available Purpose: To report outcomes in breast cancer patients with prior breast augmentation treated with external beam accelerated partial breast irradiation (EB-APBI utilizing intensity modulated radiotherapy (IMRT or 3-dimensional conformal radiotherapy (3D-CRT, both with image-guided radiotherapy (IGRT.Methods and Materials: 16 stage 0/I breast cancer patients with previous elective bilateral augmentation were treated post-lumpectomy on institutional EB-APBI trials (01185132 and 01185145 on clinicaltrials.gov. Patients received 38.5 Gy in 10 fractions over 5 consecutive days. Breast/chest wall pain and cosmesis were rated by patient; cosmesis was additionally evaluated by physician per RTOG criteria.Results: The median follow-up from APBI completion was 18.0 months (range, 1.2-58.6. Little to no change in cosmesis or pain from baseline was reported. Cosmetic outcomes at last follow-up were judged by patients as excellent/good in 93.8% (15/16, and by physicians as excellent/good in 100% (16/16. Eight patients (50.0% reported no breast/chest wall pain, and the remaining 8 patients (50.0% reported mild pain. All patients remain disease free at last follow-up. The median ipsilateral breast, planning target volume (PTV, and implant volumes were 614 cc, 57 cc, and 333 cc. The median ratios of PTV/ipsilateral breast volume (implant excluded and PTV/total volume (implant included were 9% and 6%. Conclusions: These 16 breast cancer cases with prior bilateral breast augmentation treated with external beam APBI demonstrate favorable clinical outcomes. Further exploration of external beam APBI as a treatment option for this patient po

  20. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

    Directory of Open Access Journals (Sweden)

    Siri Tähtinen

    Full Text Available Unfavorable ratios between the number and activation status of effector and suppressor immune cells infiltrating the tumor contribute to resistance of solid tumors to T-cell based therapies. Here, we studied the capacity of FDA and EMA approved recombinant cytokines to manipulate this balance in favor of efficient anti-tumor responses in B16.OVA melanoma bearing C57BL/6 mice. Intratumoral administration of IFN-α2, IFN-γ, TNF-α, and IL-2 significantly enhanced the anti-tumor effect of ovalbumin-specific CD8+ T-cell (OT-I therapy, whereas GM-CSF increased tumor growth in association with an increase in immunosuppressive cell populations. None of the cytokines augmented tumor trafficking of OT-I cells significantly, but injections of IFN-α2, IFN-γ and IL-2 increased intratumoral cytokine secretion and recruitment of endogenous immune cells capable of stimulating T-cells, such as natural killer and maturated CD11c+ antigen-presenting cells. Moreover, IFN-α2 and IL-2 increased the levels of activated tumor-infiltrating CD8+ T-cells concomitant with reduction in the CD8+ T-cell expression of anergy markers CTLA-4 and PD-1. In conclusion, intratumoral administration of IFN-α2, IFN-γ and IL-2 can lead to immune sensitization of the established tumor, whereas GM-CSF may contribute to tumor-associated immunosuppression. The results described here provide rationale for including local administration of immunostimulatory cytokines into T-cell therapy regimens. One appealing embodiment of this would be vectored delivery which could be advantageous over direct injection of recombinant molecules with regard to efficacy, cost, persistence and convenience.

  1. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.

    Science.gov (United States)

    Tähtinen, Siri; Kaikkonen, Saija; Merisalo-Soikkeli, Maiju; Grönberg-Vähä-Koskela, Susanna; Kanerva, Anna; Parviainen, Suvi; Vähä-Koskela, Markus; Hemminki, Akseli

    2015-01-01

    Unfavorable ratios between the number and activation status of effector and suppressor immune cells infiltrating the tumor contribute to resistance of solid tumors to T-cell based therapies. Here, we studied the capacity of FDA and EMA approved recombinant cytokines to manipulate this balance in favor of efficient anti-tumor responses in B16.OVA melanoma bearing C57BL/6 mice. Intratumoral administration of IFN-α2, IFN-γ, TNF-α, and IL-2 significantly enhanced the anti-tumor effect of ovalbumin-specific CD8+ T-cell (OT-I) therapy, whereas GM-CSF increased tumor growth in association with an increase in immunosuppressive cell populations. None of the cytokines augmented tumor trafficking of OT-I cells significantly, but injections of IFN-α2, IFN-γ and IL-2 increased intratumoral cytokine secretion and recruitment of endogenous immune cells capable of stimulating T-cells, such as natural killer and maturated CD11c+ antigen-presenting cells. Moreover, IFN-α2 and IL-2 increased the levels of activated tumor-infiltrating CD8+ T-cells concomitant with reduction in the CD8+ T-cell expression of anergy markers CTLA-4 and PD-1. In conclusion, intratumoral administration of IFN-α2, IFN-γ and IL-2 can lead to immune sensitization of the established tumor, whereas GM-CSF may contribute to tumor-associated immunosuppression. The results described here provide rationale for including local administration of immunostimulatory cytokines into T-cell therapy regimens. One appealing embodiment of this would be vectored delivery which could be advantageous over direct injection of recombinant molecules with regard to efficacy, cost, persistence and convenience. PMID:26107883

  2. Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells.

    Science.gov (United States)

    Rato, Luís; Alves, Marco G; Duarte, Ana I; Santos, Maria S; Moreira, Paula I; Cavaco, José E; Oliveira, Pedro F

    2015-09-01

    The incidence of type 2 diabetes mellitus and its prodromal stage, pre-diabetes, is rapidly increasing among young men, leading to disturbances in testosterone synthesis. However, the impact of testosterone deficiency induced by these progressive stages of diabetes on the metabolic behavior of Sertoli cells remains unknown. We evaluated the effects of testosterone deficiency associated with pre-diabetes and type 2 diabetes on Sertoli cells metabolism, by measuring (1) the expression and/or activities of glycolysis and glycogen metabolism-related proteins and (2) the metabolite secretion/consumption in Sertoli cells obtained from rat models of different development stages of the disease, to unveil the mechanisms by which testosterone deregulation may affect spermatogenesis. Glucose and pyruvate uptake were decreased in cells exposed to the testosterone concentration found in pre-diabetic rats (600nM), whereas the decreased testosterone concentrations found in type 2 diabetic rats (7nM) reversed this profile. Lactate production was not altered, although the expression and/or activity of lactate dehydrogenase and monocarboxylate transporter 4 were affected by progressive testosterone-deficiency. Sertoli cells exposed to type 2 diabetic conditions exhibited intracellular glycogen accumulation. These results illustrate that gradually reduced levels of testosterone, induced by progressive stages of diabetes mellitus, favor a metabolic reprogramming toward glycogen synthesis. Our data highlights a pivotal role for testosterone in the regulation of spermatogenesis metabolic support by Sertoli cells, particularly in individuals suffering from metabolic diseases. Such alterations may be in the basis of male subfertility/infertility associated with the progression of diabetes mellitus. PMID:26148570

  3. IL-1β inhibits ILC3 while favoring NK-cell maturation of umbilical cord blood CD34(+) precursors.

    Science.gov (United States)

    Ambrosini, Paolo; Loiacono, Fabrizio; Conte, Romana; Moretta, Lorenzo; Vitale, Chiara; Mingari, Maria Cristina

    2015-07-01

    NK cells are innate lymphocytes characterized by the expression of nuclear factor interleukin 3 regulated (NFIL3 or E4BP4), eomesodermin (EOMES) transcription factors (TFs), and by the ability to exert cytolytic activity and release IFN-γ. In the haploidentical-hematopoietic stem cell transplantation (haplo-HSCT) setting, CD34(+) donor derived NK cells play a major role in the control of leukemic relapses. Therefore, it is important to better define cytokines that influence NK-cell differentiation from CD34(+) precursors. We analyzed the effects of IL-1β on NK-cell differentiation from umbilical cord blood (UCB) CD34(+) cells. While IL-1β inhibited CD161(+) CD56(+) cell proliferation, an increased expression of LFA-1, CD94/NKG2A, KIRs, and perforin on CD56(+) cells was detected. In addition, within the CD161(+) CD56(+) IL-1RI(+) LFA-1(-) cell fraction (representing group 3 innate lymphoid cells, ILC3-like cells), a significant increase of EOMES, NKp46, and CD94/NKG2A receptors, cytolytic granules, and IFN-γ was detected. This increase was paralleled by a decrease of related orphan receptors (RORγt) TF, NKp44 expression, and IL-22 production. These data suggest that IL-1β inhibits ILC3- while favoring NK-cell maturation. Since in haplo-HSCT conditioning regimen, infections or residual leukemia cells may induce IL-1β production, this may influence the NK/ILC3 development from donor-derived CD34(+) precursors. PMID:25847448

  4. Pomegranate juice polyphenols induce a phenotypic switch in macrophage polarization favoring a M2 anti-inflammatory state.

    Science.gov (United States)

    Aharoni, Saar; Lati, Yoni; Aviram, Michael; Fuhrman, Bianca

    2015-01-01

    It was documented that pomegranate has anti-inflammatory effects. In this study, we investigated a direct effect of pomegranate juice (PJ) and its polyphenols on macrophage inflammatory phenotype. In vitro, PJ and its major polyphenols dose-dependently attenuated macrophage response to M1 proinflammatory activation in J774.A1 macrophage-like cell line. This was evidenced by a significant decrease in TNFα and IL-6 secretion in response to stimulation by IFNγ and Lipopolysaccharide. In addition, PJ and punicalagin dose-dependently promoted the macrophages toward a M2 anti-inflammatory phenotype, as determined by a significant increase in the spontaneous secretion of IL-10. In mice, supplementation with dietary PJ substantially inhibited the M2 to M1 macrophage phenotypic shift associated with age, toward a favorable anti-inflammatory M2 phenotype. This effect was also reflected in the mice atherosclerotic plaques, as evaluated by the distinct expression of arginase isoforms. PJ consumption inhibited the increment of arginase II (Arg II, M1) mRNA expression during aging, and maintained the levels of Arg I (M2) expression similar to those in young mice aorta. This study demonstrates, for the first time, that pomegranate polyphenols directly suppress macrophage inflammatory responses and promote M1 to M2 switch in macrophage phenotype. Furthermore, this study indicates that PJ consumption may inhibit the progressive proinflammatory state in the aorta along atherosclerosis development with aging, due to a switch in macrophage phenotype from proinflammatory M1 to anti-inflammatory M2. PMID:25650983

  5. High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

    International Nuclear Information System (INIS)

    Bcl-2 promotes cell survival by inhibiting adapters needed for the activation and cleavage of caspases thus blocking the proteolytic cascade that ultimately dismantles the cell. Bcl-2 has been investigated as a prognostic factor in non small cell lung cancer (NSCLC) patients with conflicting results. Here, we quantitatively assessed Bcl-2 expression in two large and independent cohorts to investigate the impact of Bcl-2 on survival. AQUA®, a fluorescent-based method for analysis of in situ protein expression, was used to measure Bcl-2 protein levels and classify tumors by Bcl-2 expression in a cohort of 180 NSCLC patients. An independent cohort of 354 NSCLC patients was used to validate Bcl-2 classification and evaluate outcome. Fifty % and 52% of the cases were classified as high expressers in training and validation cohorts respectively. Squamous cell carcinomas were more likely to be high expressers compared to adenocarcinomas (63% vs. 45%, p = 0.002); Bcl-2 was not associated with other clinical or pathological characteristics. Survival analysis showed that patients with high BCL-2 expression had a longer median survival compared to low expressers (22 vs. 17.5 months, log rank p = 0.014) especially in the subset of non-squamous tumors (25 vs. 13.8 months, log rank p = 0.04). Multivariate analysis revealed an independent lower risk for all patients with Bcl-2 expressing tumors (HR = 0.53, 95% CI 0.37-0.75, p = 0.0003) and for patients with non-squamous tumors (HR = 0.5, 95% CI 0.31-0.81, p = 0.005). Bcl-2 expression defines a subgroup of patients with a favorable outcome and may be useful for prognostic stratification of NSCLC patients

  6. Loss of CRABP-II Characterizes Human Skin Poorly Differentiated Squamous Cell Carcinomas and Favors DMBA/TPA-Induced Carcinogenesis.

    Science.gov (United States)

    Passeri, Daniela; Doldo, Elena; Tarquini, Chiara; Costanza, Gaetana; Mazzaglia, Donatella; Agostinelli, Sara; Campione, Elena; Di Stefani, Alessandro; Giunta, Alessandro; Bianchi, Luca; Orlandi, Augusto

    2016-06-01

    Retinol and its derivatives play an important role in epidermal growth and differentiation and represent chemopreventive agents in nonmelanoma skin cancer. Retinoic acid binding protein II (CRABP-II) is a cytoplasmic receptor that critically regulates all-trans-retinoic acid (ATRA) trafficking. We documented the marked reduced expression of CRABP-II and its promoter methylation in human poorly differentiated squamous cell carcinomas. To investigate the role of CRABP-II in skin carcinogenesis we used skin lesion induction by dimethylbenz[a]anthracene/12-O-tetradecanoyl-phorbol-13-acetate in CRABP-II-knockout C57BL/6 mice. We observed earlier and more diffuse epidermal dysplasia, greater incidence and severity of tumors, reduced expression of cytokeratin 1/cytokeratin 10 and involucrin, increased proliferation, and impaired ATRA inhibition of tumor promotion compared with wild-type animals. CRABP-II-transfected HaCaT, FaDu, and A431 cells showed expression of differentiation markers, retinoic acid receptor-β/-γ signaling, ATRA sensitivity, and suppression of EGFR/v-akt murine thymoma viral oncogene homolog 1 (AKT) pathways in a fatty acid binding protein 5/peroxisome proliferator-activated receptor-β/-δ-independent manner. The opposite was true in keratinocytes isolated from CRABP-II-knockout mice. Finally, CRABP-II accumulation induced ubiquitination-associated reduction of EGFR. Our results showed reduced CRABP-II expression in human poorly differentiated squamous cell carcinomas, and its gene deletion favored experimental skin carcinogenesis and impaired ATRA antitumor efficacy, likely modulating EGFR/AKT pathways and retinoic acid receptor-β/-γ signaling. Therapeutic interventions aimed at restoring CRABP-II-mediated signaling may amplify therapeutic retinoid efficacy in nonmelanoma skin cancer. PMID:26945879

  7. Subboiling Moist Heat Favors the Selection of Enteric Pathogen Clostridium difficile PCR Ribotype 078 Spores in Food

    Science.gov (United States)

    Rodriguez-Palacios, Alexander; Ilic, Sanja; LeJeune, Jeffrey T.

    2016-01-01

    Emerging enteric pathogens could have not only more antibiotic resistance or virulence traits; they could also have increased resistance to heat. We quantified the effects of minimum recommended cooking and higher temperatures, individually on a collection of C. difficile isolates and on the survival probability of a mixture of emerging C. difficile strains. While minimum recommended cooking time/temperature combinations (63–71°C) allowed concurrently tested strains to survive, higher subboiling temperatures reproducibly favored the selection of newly emerging C. difficile PCR ribotype 078. Survival ratios for “ribotypes 078” :  “other ribotypes” (n = 49 : 45 isolates) from the mid-2000s increased from 1 : 1 and 0.7 : 1 at 85°C (for 5 and 10 minutes, resp.) to 2.3 : 1 and 3 : 1 with heating at 96°C (for 5 and 10 minutes, resp.) indicating an interaction effect between the heating temperature and survival of C. difficile genotypes. In multistrain heating experiments, with PCR ribotypes 027 and 078 from 2004 and reference type strain ATCC 9689 banked in the 1970s, multinomial logistic regression (P < 0.01) revealed PCR ribotype 078 was the most resistant to increasing lethal heat treatments. Thermal processes (during cooking or disinfection) may contribute to the selection of emergent specific virulent strains of C. difficile. Despite growing understanding of the role of cooking on human evolution, little is known about the role of cooking temperatures on the selection and evolution of enteric pathogens, especially spore-forming bacteria.

  8. Porosity and Permeability of Round Top Mountain Rhyolite (Texas, USA Favor Coarse Crush Size for Rare Earth Element Heap Leach

    Directory of Open Access Journals (Sweden)

    Lorraine Negron

    2016-02-01

    Full Text Available Water-saturation porosity and dye-penetration permeability measurements of Round Top Mountain rhyolite confirm that a ½-inch (13-mm crush size would permit efficient acid heap leaching of yttrium and heavy rare earth elements (YHREEs hosted in yttrofluorite, a YHREE-substituted variety of fluorite. Laboratory acid leaching has extracted up to 90% of the YHREEs. The bulk insoluble gangue mineralogy of the rhyolite, 90% to 95% quartz and feldspars, assures low acid consumption. Different crush sizes were weighed, soaked in water, and reweighed over time to determine water-penetration estimated porosity. Typical porosities were 1% to 2% for gray and 3% to 8% for pink varieties of Round Top rhyolite. The same samples were re-tested after soaking in dilute sulfuric to simulate heap leaching effects. Post-leach porosity favorably increased 15% in pink and 50% in gray varieties, due to internal mineral dissolution. Next, drops of water-based writing ink were placed on rhyolite slabs up to ~10 mm thick, and monitored over time for visual dye breakthrough to the lower side. Ink penetration through 0.5 to 2.5-mm-thick slabs was rapid, with breakthrough in minutes to a few hours. Pink rhyolite breakthrough was faster than gray. Thicker slabs, 4 to 10 mm, took hours to three days for breakthrough. Porosity and permeability of the Round Top rhyolite and acid solubility of the yttrofluorite host should permit liberation of YHREEs from the bulk rock by inexpensive heap leaching at a coarse and inexpensive nominal ½-inch (13-mm crush size. The rate-limiting step in heap leach extraction would be diffusion of acid into, and back-diffusion of dissolution products out of, the crushed particles. The exceptional porosity and permeability that we document at Round Top suggest that there may be other crystalline rock deposits that economically can be exploited by a coarse-crush bulk heap leach approach.

  9. Causes of Death in Men With Prevalent Diabetes and Newly Diagnosed High- Versus Favorable-Risk Prostate Cancer

    International Nuclear Information System (INIS)

    Purpose: To determine whether prevalent diabetes mellitus (pDM) affects the presentation, extent of radiotherapy, or prostate cancer (PCa)-specific mortality (PCSM) and whether PCa aggressiveness affects the risk of non-PCSM, DM-related mortality, and all-cause mortality in men with pDM. Methods: Between October 1997 and July 2907, 5,279 men treated at the Chicago Prostate Cancer Center with radiotherapy for PCa were included in the study. Logistic and competing risk regression analyses were performed to assess whether pDM was associated with high-grade PCa, less aggressive radiotherapy, and an increased risk of PCSM. Competing risks and Cox regression analyses were performed to assess whether PCa aggressiveness described by risk group in men with pDM was associated with the risk of non-PCSM, DM-related mortality, and all-cause mortality. Analyses were adjusted for predictors of high-grade PCa and factors that could affect treatment extent and mortality. Results: Men with pDM were more likely (adjusted hazard ratio [AHR], 1.9; 95% confidence interval [CI], 1.3-2.7; p = .002) to present with high-grade PCa but were not treated less aggressively (p = .33) and did not have an increased risk of PCSM (p = .58) compared to men without pDM. Among the men with pDM, high-risk PCa was associated with a greater risk of non-PCSM (AHR, 2.2; 95% CI, 1.1-4.5; p = .035), DM-related mortality (AHR, 5.2; 95% CI, 2.0-14.0; p = .001), and all-cause mortality (AHR, 2.4; 95% CI, 1.2-4.7; p = .01) compared to favorable-risk PCa. Conclusion: Aggressive management of pDM is warranted in men with high-risk PCa.

  10. Host modulation by a parasite: how Leishmania infantum modifies the intestinal environment of Lutzomyia longipalpis to favor its development.

    Directory of Open Access Journals (Sweden)

    Vania Cristina Santos

    Full Text Available Some reports have described the interference of Leishmania on sand flies physiology, and such behavior most likely evolved to favor the development and transmission of the parasite. Most of these studies showed that Leishmania could modulate the level of proteases in the midgut after an infective blood meal, and decreased proteolytic activity is indeed beneficial for the development of promastigotes in the gut of sand flies. In the present study, we performed a detailed investigation of the intestinal pH in Lutzomyia longipalpis females naturally infected with Leishmania infantum and investigated the production of trypsin by these insects using different approaches. Our results allowed us to propose a mechanism by which these parasites interfere with the physiology of L. longipalpis to decrease the production of proteolytic enzymes. According to our hypothesis L. infantum promastigotes indirectly interfere with the production of trypsin by modulating the mechanism that controls the intestinal pH via the action of a yet non-identified substance released by promastigote forms inside the midgut. This substance is not an acid, whose action would be restrict on to release H+ to the medium, but is a substance that is able to interfere with midgut physiology through a mechanism involving pH control. According to our hypothesis, as the pH decreases, the proteolytic enzymes efficiency is also reduced, leading to a decline in the supply of amino acids to the enterocytes: this decline reduces the stimulus for protease production because it is regulated by the supply of amino acids, thus leading to a delay in digestion.

  11. The time-profile of cell growth in fission yeast: model selection criteria favoring bilinear models over exponential ones

    Directory of Open Access Journals (Sweden)

    Sveiczer Akos

    2006-03-01

    Full Text Available Abstract Background There is considerable controversy concerning the exact growth profile of size parameters during the cell cycle. Linear, exponential and bilinear models are commonly considered, and the same model may not apply for all species. Selection of the most adequate model to describe a given data-set requires the use of quantitative model selection criteria, such as the partial (sequential F-test, the Akaike information criterion and the Schwarz Bayesian information criterion, which are suitable for comparing differently parameterized models in terms of the quality and robustness of the fit but have not yet been used in cell growth-profile studies. Results Length increase data from representative individual fission yeast (Schizosaccharomyces pombe cells measured on time-lapse films have been reanalyzed using these model selection criteria. To fit the data, an extended version of a recently introduced linearized biexponential (LinBiExp model was developed, which makes possible a smooth, continuously differentiable transition between two linear segments and, hence, allows fully parametrized bilinear fittings. Despite relatively small differences, essentially all the quantitative selection criteria considered here indicated that the bilinear model was somewhat more adequate than the exponential model for fitting these fission yeast data. Conclusion A general quantitative framework was introduced to judge the adequacy of bilinear versus exponential models in the description of growth time-profiles. For single cell growth, because of the relatively limited data-range, the statistical evidence is not strong enough to favor one model clearly over the other and to settle the bilinear versus exponential dispute. Nevertheless, for the present individual cell growth data for fission yeast, the bilinear model seems more adequate according to all metrics, especially in the case of wee1Δ cells.

  12. Hanford Reach - Snively Basin Rye Field Rehabilitation

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Snively Basin area of the Arid Lands Ecology Reserve within the Hanford Reach National Monument was historically used to farm cereal rye (Secale cereale), among...

  13. Gulf Coast Basins and Uplifts [gcstructsg

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — These data provide generalized outlines of major basins and uplifts in the Gulf Coast region modified after Plate 2, Principal structural features, Gulf of Mexico...

  14. KE Basin water dispositioning engineering study

    International Nuclear Information System (INIS)

    This engineering study is a feasibility study of KE Basin water treatment to an acceptable level and dispositioning the treated water to Columbia River, ground through ETF or to air through evaporation

  15. USGS Streamgage NHDPlus Version 1 Basins 2011

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This dataset represents 19,031 basin boundaries and their streamgage locations for the U.S. Geological Survey's (USGS) active and historical streamgages from the...

  16. K-Basins S/RIDS

    Energy Technology Data Exchange (ETDEWEB)

    Watson, D.J.

    1997-08-01

    The Standards/Requirements Identification Document (S/RID) is a list of the Environmental, Safety, and Health (ES{ampersand}H) and Safeguards and Security (SAS) standards/requirements applicable to the K Basins facility.

  17. 183-H Basin sludge treatability test report

    International Nuclear Information System (INIS)

    This document presents the results from the treatability testing of a 1-kg sample of 183-H Basin sludge. Compressive strength measurements, Toxic Characteristic Leach Procedure, and a modified ANSI 16.1 leach test were conducted

  18. Overflow of Radioactive Water from K Basins

    International Nuclear Information System (INIS)

    This report documents the dose calculations for the postulated K Basin overflow accident using current methods to model the environmental doses for radioactive releases into the Columbia River and the air

  19. K-Basins S/RIDS

    Energy Technology Data Exchange (ETDEWEB)

    Watson, D.J.

    1995-09-22

    The Standards/Requirements Identification Document(S/RID) is a list of the Environmental, Safety, and Health (ES&H) and Safeguards and Security (SAS) standards/requirements applicable to the K Basins facility

  20. K-Basins S/RIDS

    International Nuclear Information System (INIS)

    The Standards/Requirements Identification Document (S/RID) is a list of the Environmental, Safety, and Health (ES(ampersand)H) and Safeguards and Security (SAS) standards/requirements applicable to the K Basins facility

  1. Cretaceous Onlap, Gulf of Mexico Basin [cretonlapg

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The maximum extent of Cretaceous onlap is generalized from Plate 3, Structure at the base and subcrop below Mesozoic marine section, Gulf of Mexico Basin (compiled...

  2. Klamath Basin Water Rights Place of Use

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Hydrological Information Products for the Off-Project Water Program of the Klamath Basin Restoration Agreement U.S. Geological Survey Open-File Report 2012-1199...

  3. River Basin Standards Interoperability Pilot

    Science.gov (United States)

    Pesquer, Lluís; Masó, Joan; Stasch, Christoph

    2016-04-01

    There is a lot of water information and tools in Europe to be applied in the river basin management but fragmentation and a lack of coordination between countries still exists. The European Commission and the member states have financed several research and innovation projects in support of the Water Framework Directive. Only a few of them are using the recently emerging hydrological standards, such as the OGC WaterML 2.0. WaterInnEU is a Horizon 2020 project focused on creating a marketplace to enhance the exploitation of EU funded ICT models, tools, protocols and policy briefs related to water and to establish suitable conditions for new market opportunities based on these offerings. One of WaterInnEU's main goals is to assess the level of standardization and interoperability of these outcomes as a mechanism to integrate ICT-based tools, incorporate open data platforms and generate a palette of interchangeable components that are able to use the water data emerging from the recently proposed open data sharing processes and data models stimulated by initiatives such as the INSPIRE directive. As part of the standardization and interoperability activities in the project, the authors are designing an experiment (RIBASE, the present work) to demonstrate how current ICT-based tools and water data can work in combination with geospatial web services in the Scheldt river basin. The main structure of this experiment, that is the core of the present work, is composed by the following steps: - Extraction of information from river gauges data in OGC WaterML 2.0 format using SOS services (preferably compliant to the OGC SOS 2.0 Hydrology Profile Best Practice). - Model floods using a WPS 2.0, WaterML 2.0 data and weather forecast models as input. - Evaluation of the applicability of Sensor Notification Services in water emergencies. - Open distribution of the input and output data as OGC web services WaterML, / WCS / WFS and with visualization utilities: WMS. The architecture

  4. Basin development and petroleum prospects of central New Hebrides arc

    Energy Technology Data Exchange (ETDEWEB)

    Greene, H.G.; Wong, F.L.; Falvey, D.A.; MacFarlane, A.

    1986-07-01

    Two extensive intra-arc basins, the Central basin of Vanuatu and the Vanikolo basin, have recently been mapped in detail and appear to have developed in the last 3 m.y. primarily from subduction and arc-polarity reversal. The Central basin of Vanuatu is being modified by the ridge-arc collision and is still accumulating sediment, whereas the Vanikolo basin has no physiographic expression and is completely filled with sediment. Quaternary volcanism has separated the Central basin of Vanuatu into two physiographic basins (North Aoba and South Aoba basins). The Central basin is flanked on the west by five smaller insular basins associated with the islands of Malakula and Espiritu Santo. Although North and South Aoba basins lie in water depths as great as 3 km, migration paths into the shallower water basins appear to be present, and structures that could trap hydrocarbons occur. More than 5 km of sediment of Miocene and younger age were deposited in the deeper basins, whereas 2-km thick sediments of late Miocene and younger age occur near the islands. The most promising hydrocarbon basin is Malakula basin, which lies on the eastern shelf of Malakula Island, where onshore source rock analyses indicated potential gas concentrations. North of the Central basin of Vanuatu lies the largest basin in the region, the Vanikolo basin, covering more than 14,000 km/sup 2/ and containing more than 6 km of probablen Miocene and younger sediment. Water depths are more than 2 km in the deepest part of this basin, but much of the margins lie in water less than 1 km deep. Structures along the margins could trap hydrocarbons, especially along the western side, and are accessible to drilling. More work must be done in Vanikolo basin to assess hydrocarbon source rocks, migration, and heat flow before a comprehensive hydrocarbon evaluation can be made.

  5. Petroleum Exploration Prospects in Erlian Basin,China

    Institute of Scientific and Technical Information of China (English)

    Fei Baosheng

    1994-01-01

    @@ Erlian Basin is located in the middle prairie,Inner Mongolia Autonomous Region, the north border of China. Teetonieally, Erlian Basin is to the south of Bayinbaoligel Uplift and the north is the Wendouer Temple Uplift. In the east of the basin, there is Daxinganling Uplift and the west is Soulunshan Uplift. The basin covered an area of 100 000 km2, is a Mesozoic Cenozoic graben (rift)basin that evolved on the folded basement of Heveynian geosyncline.

  6. Microbiology of spent nuclear fuel storage basins.

    Science.gov (United States)

    Santo Domingo, J W; Berry, C J; Summer, M; Fliermans, C B

    1998-12-01

    Microbiological studies of spent nuclear fuel storage basins at Savannah River Site (SRS) were performed as a preliminary step to elucidate the potential for microbial-influenced corrosion (MIC) in these facilities. Total direct counts and culturable counts performed during a 2-year period indicated microbial densities of 10(4) to 10(7) cells/ml in water samples and on submerged metal coupons collected from these basins. Bacterial communities present in the basin transformed between 15% and 89% of the compounds present in Biologtrade mark plates. Additionally, the presence of several biocorrosion-relevant microbial groups (i.e., sulfate-reducing bacteria and acid-producing bacteria) was detected with commercially available test kits. Scanning electron microscopy and X-ray spectra analysis of osmium tetroxide-stained coupons demonstrated the development of microbial biofilm communities on some metal coupons submerged for 3 weeks in storage basins. After 12 months, coupons were fully covered by biofilms, with some deterioration of the coupon surface evident at the microscopical level. These results suggest that, despite the oligotrophic and radiological environment of the SRS storage basins and the active water deionization treatments commonly applied to prevent electrochemical corrosion in these facilities, these conditions do not prevent microbial colonization and survival. Such microbial densities and wide diversity of carbon source utilization reflect the ability of the microbial populations to adapt to these environments. The presumptive presence of sulfate-reducing bacteria and acid-producing bacteria and the development of biofilms on submerged coupons indicated that an environment for MIC of metal components in the storage basins may occur. However, to date, there has been no indication or evidence of MIC in the basins. Basin chemistry control and corrosion surveillance programs instituted several years ago have substantially abated all corrosion mechanisms

  7. Comprehensive analysis of sustainable flood retention basins

    OpenAIRE

    Yang, Qinli

    2011-01-01

    To adapt to climate change which results in increasing flood frequency and intensity, the European Community has proposed Flood Directive 2007/60/EC. It requires member states to conduct risk assessments of all river basins and coastal areas and to establish Flood Risk Management Plans focused on prevention, protection and preparedness by 2015. Sustainable Flood Retention Basins (SFRB) that impound water are a new concept that arose in 2006. They can have a pre-defined or po...

  8. Geo-economy of the Caspian basin

    International Nuclear Information System (INIS)

    The Caspian area is essential for the development of the central Asia countries and Caucasus. Excepted the Iran and the Russia, these areas economy is poor. The hydrocarbons exploitation should reinforce the economic weight of these States. The author analyzes the Caspian area economies and shows that the basin economies are confronted with three handicaps, and that even with different economic ways, the soviet economic system is still present in the basin. (A.L.B.)

  9. ALLUVIUM RUNOFF STUDY IN GILORT HYDROGRAPHIC BASIN

    Directory of Open Access Journals (Sweden)

    GRIGORE CIOCĂZAN

    2012-04-01

    Full Text Available The study aims the characterization of the solid runoff in the Gilort hydrographic basin, analyzing the variations in time (for the period 1982-2007 and in space (for the three major relief units in the basin of this parameter. The data came from the three hydrometric stations where are performed the measurements for the alluvium runoff: Ciocadia, Târgu-Cărbuneşti (Gilort river and Turburea.

  10. THE RIVER BASIN APPROACH IN TOURISM PLANNING

    OpenAIRE

    Slara, Agita

    2005-01-01

    The article describes advantages and disadvantages in tourism planning, using the river basins as background territory and borders. Tourism development planning is taking place according administrative territorial borders till nowadays in Latvia and in other tourism destinations in abroad. According tourist and visitor needs and environmental friendly approach it is more appropriate to use river basins in tourism planning. Tourists are not interested in administrative borders, but in qualitat...

  11. Meso-cenozoic tectonic evolution character and metallogenesis of sandstone-type uranium deposits in Tarim Basin

    International Nuclear Information System (INIS)

    Based on comprehensive analyses on tectonic evolution of Tarim Basin and combined with isotopic ages of ores, the metallogenic stages of sandstone-type uranium deposits in the basin have been divided, the control of structures on ore-bearing strata and epigenetically altered metallogenic processes have been studied and it is believed that the structures before the last large-scale Himalayan Orogeny(before N2) are favorable for metallogenesis of sandstone-type uranium deposits and those after the Himalayan Orogeny mainly altered the ore bodies formed earlier. The metallogenic models for deposits controlled by structures have been studied and it is concluded that Kujieertai-type uranium deposits were formed in weakly deformed parts of structures, Sawabuqi-type uranium deposits were formed in strongly deformed parts of structures and however, Bashibulake-type uranium deposits were formed in the original red or mottled strata of K-N. (authors)

  12. Shear-flow transition: the basin boundary

    International Nuclear Information System (INIS)

    The basin of attraction of a stable equilibrium point is investigated for a dynamical system (W97) that has been used to model transition to turbulence in shear flows. The basin boundary contains a linearly unstable equilibrium point Xlb which, in the self-sustaining scenario, plays a role in mediating the transition in that transition orbits cluster around its unstable manifold. However we find—for W97 with canonical parameter values—that this role is played not by Xlb but rather by a periodic orbit also lying on the basin boundary. Moreover, it appears via numerical computations that all orbits beginning near Xlb relaminarize. We offer numerical evidence that the parameter values of W97 are post-critical in the following sense: for some, subcritical parameter values, the basin boundary coincides with the stable manifold of Xlb and only a subset of nearby orbits relaminarize, whereas for supercritical values the basin boundary is the union of two stable manifolds, one belonging to the periodic orbit and dominating the basin boundary, and the other belonging to Xlb and detectable only as edge separating relaminarizing orbits of different characters. The periodic orbit appears at the critical parameter value via a homoclinic connection. This further leads to a proposal for the structure of the 'edge of chaos' somewhat different from that which has previously been proposed

  13. Lunar basin formation and highland stratigraphy

    Science.gov (United States)

    Howard, K. A.; Wilhelms, D. E.; Scott, D. H.

    1974-01-01

    Multiring impact basins, formed after solidification of the lunar crust, account for most or all premare regional deposits and structures expressed in the lunar landscape and for major topographic and gravity variations. A fresh basin has two or more concentric mountain rings, a lineated ejecta blanket, and secondary impact craters. Crackled material on the floor may be impact melt. The ejecta blanket was emplaced at least partly as a ground-hugging flow and was probably hot. A suggested model of basin formation is that the center lifts up and the rings form by inward collapse during evisceration. The resulting basin is shallow and has a central uplift of the mantle. This results in a central gravity high and a ring low. Later flooding by mare basalt has since modified most near side basins. Highland deposits of plains, furrowed and pitted terrain, and various hills, domes, and craters that were interpreted before the Apollo missions as being volcanic can now be interpreted as being basin related.

  14. K basins sludge removal sludge pretreatment system

    International Nuclear Information System (INIS)

    The Spent Nuclear Fuels Program is in the process of planning activities to remove spent nuclear fuel and other materials from the 100-K Basins as a remediation effort for clean closure. The 105 K- East and K-West Basins store spent fuel, sludge, and debris. Sludge has accumulated in the 1 00 K Basins as a result of fuel oxidation and a slight amount of general debris being deposited, by settling, in the basin water. The ultimate intent in removing the sludge and fuel is to eliminate the environmental risk posed by storing fuel at the K Basins. The task for this project is to disposition specific constituents of sludge (metallic fuel) to produce a product stream through a pretreatment process that will meet the requirements, including a final particle size acceptable to the Tank Waste Remediation System (TWRS). The purpose of this task is to develop a preconceptual design package for the K Basin sludge pretreatment system. The process equipment/system is at a preconceptual stage, as shown in sketch ES-SNF-01 , while a more refined process system and material/energy balances are ongoing (all sketches are shown in Appendix C). Thus, the overall process and 0535 associated equipment have been conservatively selected and sized, respectively, to establish the cost basis and equipment layout as shown in sketches ES- SNF-02 through 08

  15. California Basin Studies (CaBS)

    International Nuclear Information System (INIS)

    The California Continental Borderland's present configuration dates from about 4 to 5 X 106 years Before Present (B.P.) and is the most recent of several configurations of the southern California margin that have evolved after the North America Plate over-rode the East Pacific Rise about 30 X 106 years ago. The present morphology is a series of two to three northwest-southeast trending rows of depressions separated by banks and insular ridges. Two inner basins, Santa Monica and San Pedro, have been the site for the Department of Energy-funded California Basin Study (CaBS) Santa Monica and San Pedro Basins contain post-Miocene sediment thicknesses of about 2.5 and 1.5 km respectively. During the Holocene (past 10,000 years) about 10-12 m have accumulated. The sediment entered the basin by one or a combination of processes including particle infall (mainly as bioaggregates) from surface waters, from nepheloid plumes (surface, mid-depths and near-bottom), from turbidity currents, mass movements, and to a very minor degree direct precipitation. In Santa Monica Basin, during the last century, particle infall and nepheloid plume transport have been the most common processes. The former dominates in the central basin floor in water depths from 900 to 945 m. where a characteristic silt-clay with a typical mean diameter of about 0.006 mm, phi standard deviation

  16. The thermal environment of Cascadia Basin

    Science.gov (United States)

    Johnson, H. Paul; Hautala, Susan L.; Bjorklund, Tor A.

    2012-07-01

    Located adjacent to the NE Pacific convergent boundary, Cascadia Basin has a global impact well beyond its small geographic size. Composed of young oceanic crust formed at the Juan de Fuca Ridge, igneous rocks underlying the basin are partially insulated from cooling of their initial heat of formation by a thick layer of pelagic and turbidite sediments derived from the adjacent North American margin. The igneous seafloor is eventually consumed at the Cascadia subduction zone, where interactions between the approaching oceanic crust and the North American continental margin are partially controlled by the thermal environment. Within Cascadia Basin, basement topographic relief varies dramatically, and sediments have a wide range of thickness and physical properties. This variation produces regional differences in heat flow and basement temperatures for seafloor even of similar age. Previous studies proposed a north-south thermal gradient within Cascadia Basin, with high geothermal flux and crustal temperatures measured in the heavily sedimented northern portion near Vancouver Island and lower than average heat flux and basement temperatures predicted for the central and southern portions of the basin. If confirmed, this prediction has implications for processes associated with the Cascadia subduction zone, including the location of the "locked zone" of the megathrust fault. Although existing archival geophysical data in the central and southern basin are sparse, nonuniformly distributed, and derived from a wide range of historical sources, a substantial N-S geothermal gradient appears to be confirmed by our present compilation of combined water column and heat flow measurements.

  17. Tectonic evolution of Tarim basin in Cambrian–Ordovician and its implication for reservoir development, NW China

    Indian Academy of Sciences (India)

    Yu Bingsong; Ruan Zhuang; Zhang Cong; Pan Yinglu; Lin Changsong; Wang Lidong

    2016-03-01

    In order to find the impact of regional tectonic evolution of Tarim basin on the inside distribution of sedimentary facies and reservoir development, this paper, based on the research of plate-tectonic evolution of Tarim basin, conducts an in-depth analysis on the basin’s inside sedimentary response to the Eopaleozoicregional geodynamic reversion from extension to convergence around Tarim plate, and concludes that the regional geodynamic environment of surrounding areas closely contributes to the formation and evolution of paleo-uplifts, differentiation of sedimentary facies in platform, distribution of high-energyreef and bank facies belts, conversion of sedimentary base level from fall to rise, obvious change of lithology from dolomite to limestone, and formation of several unconformity surfaces in Ordovician system in the basin. A series of sedimentary responses in the basin are controlled by regional dynamic setting, which not only controls the distribution of reservoirs in reef and bank facies but also restricts the development and distribution of karst reservoirs controlled by the unconformity surfaces. This offers the macro geological evidences for us to further analyze and evaluate the distribution of favorable reservoirs.

  18. PLIOCENE ALLUVIAL TO MARINE DEPOSITS OF THE VAL D’ORCIA BASIN (NORTHERN APENNINES, ITALY): SEQUENCE STRATIGRAPHY AND BASIN ANALYSIS

    OpenAIRE

    MASSIMILIANO GHINASSI

    2007-01-01

    Since the Middle-Late Miocene, the Apennine chain was characterised by the development of several basins. These basins have been alternatively explained as extensional post-orogenic basins or syn-orogenic compressional basins. In this framework, the Pliocene depositional history of the Val d'Orcia Basin (Southern Tuscany) is described, based on a sequence stratigraphic approach. Three depositional sequences (Vd3a-c) have been recognized. The Vd3a sequence records marine ingression and subsequ...

  19. Study of the Factors Affecting the Abundance of Organic Matter in Jurassic Carbonate Rocks in Qiangtang Basin, Tibet

    Institute of Scientific and Technical Information of China (English)

    文志刚; 胡明毅; 龚文平; 肖传桃

    2004-01-01

    Field and laboratory analyses of carbonate rock samples from the Qiangtang Basin,Tibet, indicate that carbonate source rocks are mainly developed in the Middle Jurassic Xiali Formation and Upper Jurassic Suowa Formation. Comprehensive studies showed that the Suowa Formation carbonate source rocks have a favorable hydrocarbon-generating potential. The abundance of organic matter in the carbonate rocks is controlled mainly by sedimentary environment and inorganic compounds in the rocks, which is higher in the restricted platform facies than in the open platform facies. Organic carbon contents decrease with increasing CaO contents in the source rocks.

  20. Estimating tectonic history through basin simulation-enhanced seismic inversion: Geoinformatics for sedimentary basins

    Science.gov (United States)

    Tandon, K.; Tuncay, K.; Hubbard, K.; Comer, J.; Ortoleva, P.

    2004-01-01

    A data assimilation approach is demonstrated whereby seismic inversion is both automated and enhanced using a comprehensive numerical sedimentary basin simulator to study the physics and chemistry of sedimentary basin processes in response to geothermal gradient in much greater detail than previously attempted. The approach not only reduces costs by integrating the basin analysis and seismic inversion activities to understand the sedimentary basin evolution with respect to geodynamic parameters-but the technique also has the potential for serving as a geoinfomatics platform for understanding various physical and chemical processes operating at different scales within a sedimentary basin. Tectonic history has a first-order effect on the physical and chemical processes that govern the evolution of sedimentary basins. We demonstrate how such tectonic parameters may be estimated by minimizing the difference between observed seismic reflection data and synthetic ones constructed from the output of a reaction, transport, mechanical (RTM) basin model. We demonstrate the method by reconstructing the geothermal gradient. As thermal history strongly affects the rate of RTM processes operating in a sedimentary basin, variations in geothermal gradient history alter the present-day fluid pressure, effective stress, porosity, fracture statistics and hydrocarbon distribution. All these properties, in turn, affect the mechanical wave velocity and sediment density profiles for a sedimentary basin. The present-day state of the sedimentary basin is imaged by reflection seismology data to a high degree of resolution, but it does not give any indication of the processes that contributed to the evolution of the basin or causes for heterogeneities within the basin that are being imaged. Using texture and fluid properties predicted by our Basin RTM simulator, we generate synthetic seismograms. Linear correlation using power spectra as an error measure and an efficient quadratic

  1. Social media for message testing: a multilevel approach to linking favorable viewer responses with message, producer, and viewer influence on YouTube.

    Science.gov (United States)

    Paek, Hye-Jin; Hove, Thomas; Jeon, Jehoon

    2013-01-01

    To explore the feasibility of social media for message testing, this study connects favorable viewer responses to antismoking videos on YouTube with the videos' message characteristics (message sensation value [MSV] and appeals), producer types, and viewer influences (viewer rating and number of viewers). Through multilevel modeling, a content analysis of 7,561 viewer comments on antismoking videos is linked with a content analysis of 87 antismoking videos. Based on a cognitive response approach, viewer comments are classified and coded as message-oriented thought, video feature-relevant thought, and audience-generated thought. The three mixed logit models indicate that videos with a greater number of viewers consistently increased the odds of favorable viewer responses, while those presenting humor appeals decreased the odds of favorable message-oriented and audience-generated thoughts. Some significant interaction effects show that videos produced by laypeople may hinder favorable viewer responses, while a greater number of viewer comments can work jointly with videos presenting threat appeals to predict favorable viewer responses. Also, for a more accurate understanding of audience responses to the messages, nuance cues should be considered together with message features and viewer influences. PMID:22583315

  2. Tectonic and climatic control on geomorphological and sedimentary evolution of the Mercure basin, southern Apennines, Italy

    Science.gov (United States)

    Robustelli, Gaetano; Ermolli, Elda Russo; Petrosino, Paola; Jicha, Brian; Sardella, Raffaele; Donato, Paola

    2014-06-01

    The morpho-tectonic and sedimentary evolution of the Mercure intramontane basin (Calabria-Lucania boundary, southern Apennines) has been assessed through facies analysis, morphostratigraphy and geomorphological correlation with adjacent areas. The Mercure basin, one of the most active seismogenic zones of the southern Apennines, is a favorable area for reconstructing the main stages of landscape evolution of the axial zone because of its capability to record changes in base level during the Quaternary. In addition, the presence of both erosional and depositional Palaeosurfaces is a useful marker for reconstructing tectonic and morphogenetic events, and hence to detect the role played by tectonics and climate in its genesis, evolution and extinction. The present study identifies the key role of tectonics and denudation, combined with high-frequency floods, as mechanisms controlling alluvial sedimentation in the study area. During endorheic conditions, denudational processes driven by pulses of extensional deformation of the basin margin caused strong alluvial inputs that resulted in the development of alluvial fans. Alluvial facies are mainly characterized by turbulent, subaerial, hyperconcentrated flood flows deposited during the glacial, semi-arid conditions of MIS 14. The retrogradational stacking pattern of the alluvial system indicates decreasing rates of tectonic activity along with declining river gradients. The Mercure coalescing alluvial fans were inundated by lake transgression during MIS 13 in response to (i) abrupt tectonic subsidence at the basin margins and (ii) large decrease of coarse sediment supply due to the interplay among climate, tectonics and catchment size changes. In this regard, it is suggested that tectonic control on the drainage network along with climate and long-term slope evolution may have caused marked pulses in sediment supply, thus influencing the arrangement of facies associations in the sedimentary succession. In addition, the

  3. Iodine mobilization in groundwater system at Datong basin, China: Evidence from hydrochemistry and fluorescence characteristics

    International Nuclear Information System (INIS)

    Characterizing the speciation of iodine in groundwater is essential for understanding its hydrogeochemical behavior in aquifer systems. To quantify the variations in iodine speciation and assess factors controlling the distribution and transformation of iodine, 82 groundwater samples and 1 rain water were collected from the Datong basin, northern China in this study. Factor analysis (FA) and excitation emission matrix with parallel factor analysis (EEM–PARAFAC) were used to clarify the potential relationships among iodine species and other hydrochemical parameters. The iodine concentrations of groundwater range from 6.23 to 1380 μg L−1 with 47% of samples exceeding its drinking water level of 150 μg L−1 as recommended by the Chinese government. 57% of samples have ratios of iodate to total iodine greater than 60%, while iodide as the major species in 22% of the samples. Significant amounts of organic iodine with concentrations higher than 100 μg L−1 were observed in 9 groundwater samples. Redox conditions of groundwater system strongly affect iodine concentration and speciation of inorganic iodine in groundwater, and extremely reducing condition restricts the iodine release from sediments into groundwater. The results of FA show that iodine mobilization in groundwater is related to the nature of dissolved organic matter. EEM-PARAFAC model demonstrates the dominance of terrestrial DOM sources and the presence of microbial activities in groundwater system of the Datong basin. It is proposed that degradation of organic matter and reductive dissolution of iron oxyhydroxides are major hydrogeochemical processes responsible for the mobilization of iodine release and the genesis of organic iodine. - Highlights: • Iodine species in groundwater was studied from Datong basin, northern China. • Weakly alkaline environment favors the accumulation of iodine in groundwater. • Iodate is the major species of iodine in groundwater from Datong basin. • Redox

  4. Controls on alkylphenol occurrence and distribution in oils from lacustrine rift basins in East China

    Institute of Scientific and Technical Information of China (English)

    ZHOU ShuQing; HUANG HaiPing

    2008-01-01

    Oils from two lacustrine rift basins in east China are thoroughly investigated using geochemical method to understand controls on alkylphenol occurrence and distribution in oils. Oils in the Lujiapu Depression,Kailu Basin are derived from the Cretaceous source rocks,and those in the Dongying Depression,Bohai Bay Basin,from the Tertiary source rocks. All oils are experienced relatively short distance of migration and have similar maturity in each basin. Differences in homologue distributions from different oilfields are most likely caused by organic facies variation of source rocks. The oils in the Lujiapu Depression are characterized by high proportion of C3 alkylphenols (prefixes refer to the number of alkylcarbons joined to the aromatic ring of the phenol molecule) and low proportion of cresols and C2 alkylphenols compared to oils from the Dongying Depression. Alkylphenol isomer distribution is possibly affected by depositional environment especially for C3 alkylphenols. Dysoxic freshwater environment is favorable for the formation of propyl or isopropyl substituted C3 alkylphenols,while highly reducing saline water is more suitable for trimethyl substituted C3 alkylphenols. Variations in alkylphenol concentrations within a petroleum system are controlled mainly by secondary migration processes with alkylphenol concentrations decreasing along migration direction. Interestingly,coupled with geological factors,a subtle change of alkylphenol concentrations can be applied to differentiate carrier systems. When oil migrates through sandy beds,concentrations of total alkylphenols decrease dramatically with migration distance,while such change is less significant when oil migrates vertically along faults. However,most isomer ratios potentially related to migration distance are not as effective as those alkylcarbazoles in migration diagnosis due to complicated affecting factors.

  5. Favorable outcomes in locally advanced and node positive prostate cancer patients treated with combined pelvic IMRT and androgen deprivation therapy

    International Nuclear Information System (INIS)

    The most appropriate treatment for men with prostate cancer and positive pelvic nodes, N+, is an area of active controversy. We report our 5-years outcomes in men with locally advanced prostate cancer (T1-T4N0-N1M0) treated with definitive radiotherapy encompassing the prostate and pelvic lymph nodes (intensity modulated radiotherapy, IMRT) and long-term androgen deprivation therapy (ADT). Of the 138 consecutive eligible men all living patients have been followed up to almost 5 years. Survival endpoints for 5-year biochemical failure-free survival (BFFS), relapse-free survival (RFS), prostate cancer-specific survival (PCSS), and overall survival (OS) were assessed by Kaplan-Meier analysis. Univariate and multivariate Cox regression proportional hazards models were constructed for all survival endpoints. The RTOG morbidity grading system for physician rated toxicity was applied. Patients with locally advanced T3-T4 tumors (35 %) and N1 (51 %) have favorable outcome when long-term ADT is combined with definitive radiotherapy encompassing pelvic lymph nodes. The 5-year BFFS, RFS, PCSS and OS were 71.4, 76.2, 94.5 and 89.0 %, respectively. High Gleason sum (9–10) had a strong independent prognostic impact on BFFS, RFS and OS (p = 0.001, <0.001, and 0.005 respectively). The duration of ADT (= > 28 months) showed a significant independent association with improved PCSS (p = 0.02) and OS (p = 0.001). Lymph node involvement was not associated with survival endpoints in the multivariate analysis. The radiotherapy induced toxicity seen in our study population was moderate with rare Grade 3 GI side effects and up to 11 % for Grade 3 GU consisting mainly of urgency and frequency. Pelvic IMRT in combination with long-term ADT can achieve long-lasting disease control in men with N+ disease and unfavorable prognostic factors. The online version of this article (doi:10.1186/s13014-015-0540-3) contains supplementary material, which is available to authorized users

  6. Geothermal systems in volcanic arcs: Volcanic characteristics and surface manifestations as indicators of geothermal potential and favorability worldwide

    Science.gov (United States)

    Stelling, P.; Shevenell, L.; Hinz, N.; Coolbaugh, M.; Melosh, G.; Cumming, W.

    2016-09-01

    This paper brings a global perspective to volcanic arc geothermal assessments by evaluating trends and correlations of volcanic characteristic and surface manifestation data from world power production sites in subduction zone volcanic settings. The focus of the work was to evaluate volcanic centers individually and as a group in these arcs by correlating various geologic characteristics with known potential to host electricity grade geothermal systems at the volcanic centers. A database was developed that describes key geologic factors expected to be indicative of productive geothermal systems in a global training set, which includes all 74 subduction zone volcanic centers world-wide with current or proven power production capability. Importantly, this data set only contains data from subduction zone volcanoes and contains no negative cases, limiting the populations of any statistical groups. Regardless, this is the most robust geothermal benchmark training set for magmatic-heated systems to date that has been made public. The work reported here is part of a larger project that included data collection, evaluation, correlations and weightings, fairway and favorability modeling and mapping, prediction of blind systems, and uncertainty analysis to estimate errors associated with model predictions. This first paper describes volcano characteristics, compositions and eruption ages and trends along with surface manifestation observations and temperatures as they relate to known power producing systems. Our findings show a strong correlation between the presence and size of active flank fumarole areas and installed power production. Additionally, the majority of volcanic characteristics, including long-held anecdotal correlations related to magmatic composition or size, have limited to no correlation with power production potential. Notable exceptions are correlations between greater power yield from geothermal systems associated with older (Pleistocene) caldera systems

  7. Brand Cigarillos: Low Price but High Particulate Matter Levels—Is Their Favorable Taxation in the European Union Justified?

    Directory of Open Access Journals (Sweden)

    Julia Wasel

    2015-08-01

    particulate matter emissions between cigarettes and cigarillos, we think that a favorable taxation of cigarillos is not justifiable.

  8. Ugandan Women’s View of the IUD: Generally Favorable but Many Have Misperceptions About Health Risks

    Science.gov (United States)

    Twesigye, Rogers; Buyungo, Peter; Kaula, Henry; Buwembo, Dennis

    2016-01-01

    ABSTRACT Background: Between 2001 and 2006, IUD use in Uganda stagnated at 0.2% among women of reproductive age (WRA) ages 15–49. By 2011, IUD use had increased slightly to 0.4%. Recent studies report a significant increase in IUD use to 3.8%, but it is still low. Because the IUD is a little-used method in Uganda, we assessed the acceptability of the IUD by surveying women about their perceptions, attitudes, and beliefs. Methods: In August and September 2014, we conducted a cross-sectional survey among 1,505 WRA exiting public and private health facilities in Uganda. We collected information on women’s attitudes, knowledge, and beliefs about the IUD, as well as their perceptions about its availability. We classified women’s responses according to a behavior change framework with 3 summary constructs: opportunity (structural factors that influence behavior), ability (skills to perform the behavior), and motivation (self-interest in adopting the behavior). As these 3 types of factors are more favorable to the desired behavior (in this case, use of the IUD), individuals are more likely to perform the behavior. Cross-tabulations compared the percentage results of perceptions and knowledge by key background characteristics. Results: Most (87.8%) of the surveyed women had heard of the IUD, and nearly two-thirds had a positive attitude toward the method. But a lower percentage (38.6%) had accurate information about the IUD and more than half (51.6%) did not think the method was available in a nearby facility. More than half of the women believed incorrectly that the IUD can damage the womb (57%), that it reduces sexual pleasure (54%), and that it can cause cancer (58%). Current use of family planning or of a modern method specifically was positively associated with awareness and accurate knowledge and beliefs about the IUD. Married women had significantly higher awareness of the IUD than single women, and they had better knowledge and belief scores. The type of

  9. Implication of drainage basin parameters of a tropical river basin of South India

    Science.gov (United States)

    Babu, K. J.; Sreekumar, S.; Aslam, Arish

    2016-03-01

    Drainage morphometry provides quantitative description of the drainage system which is an important aspect of the characterisation of watersheds. Chalakudi River is one of the important rivers of the South India which has attracted attention of many environmental scientists recently because of the proposed Athirapally Hydel Project across the river. SRTM (Shuttle Radar Topographic Mission) data were used for preparing DEM (Digital Elevation Model), Aspect Map and Slope Map. Geographical Information System (GIS) was used for the evaluation of linear, areal and relief aspects of morphometric parameters. The study reveals that the terrain exhibits dentritic and trellis pattern of drainage. The Chalakudi River Basin has a total area of 1,448.73 km2 and is designated as seventh-order basin. The drainage density of the basin is estimated as 2.54 and the lower-order streams mostly dominate the basin. The high basin relief indicates high runoff and sediment transport. The elongation ratio of the Chalakudi Basin is estimated as 0.48 and indicates that the shape of the basin is elongated. The development of stream segments in the basin area is more or less effected by rainfall. Relief ratio indicates that the discharge capability of watershed is very high and the groundwater potential is meagre. The low value of drainage density in spite of mountainous relief indicates that the area is covered by dense vegetation and resistant rocks permeated by fractures and joints. These studies are helpful in watershed development planning and wise utilization of natural resources.

  10. Some Common Issues and the Application of more Favorable Criminal Law for Crimes against the Person according to the New Criminal Code

    Directory of Open Access Journals (Sweden)

    Ion Rusu

    2015-12-01

    Full Text Available The paper examines the main common issues of crimes against the person, and some other situations of more favorable criminal law enforcement. The innovations consist in the conducted examination and the views expressed on some situations in which the more favorable criminal law should be applied. The main change with a strong preventive feature is to introduce the two institutions, namely, the renunciation of applying the punishment and postponing the punishment, which generally is given a favoring regime to physical or legal entities being at their first conflict with the law or in the case of committing crimes whose seriousness is reduced. The paper continues other papers published in the field, and it can be useful both to academics and practitioners in the domain of preventing and combating crime of this kind.

  11. A chrono-tectonostratigraphic framework for the Sydney Basin

    Science.gov (United States)

    Mohammad, O. A.; Jones, B. G.; Fergusson, C. L.

    2013-12-01

    The Sydney Basin is a foreland basin forming the southern part of the Bowen-Gunnedah-Sydney Basin system in Eastern Australia. Tectonically the Sydney Basin is regarded as a retro-arc foreland basin that developed through Late Carboniferous to Middle Triassic. Constructing a tectonstratigraphic framework for the basin is difficult due to the complex stratigraphy and poor age control, along with its complex tectonic history. A chrono-tectonostratigraphic framework for the Sydney Basin is presented based on literature synthesis combined with new data analysis. The chrono-tectonostratigraphic framework will provide an up-to-date and easy to follow detailed basin history which can be utilize in the exploration for conventional and unconventional resources in the Sydney Basin.

  12. Wave tectono-sedimentary processes in Tarim basin

    Institute of Scientific and Technical Information of China (English)

    JIN Zhijun; ZHANG Yiwei; CHEN Shuping

    2005-01-01

    Based on the unconformities, the formation times of structures, and geological wave filtering applied to basin fills of typical wells around the Manjiaer area in the Tarim basin, the wave tectono-sedimentary processes in the Tarim Basin are discussed. The results of geological wave filtering of basin fills of typical wells show that, in time domain, the evolution of the Tarim basin was controlled by various wave processes with the periods of 740±Ma, 200±Ma, 100±Ma and 30±Ma. The analyses of basin fills, basin subsidence and unconformities show that the trends of the sedimentary facies belts, depocenters, and centers of subsidence migrated and interchanged periodically with periods of 200±Ma. These show the propagation of wave movements in space domain. The wave evolution of the Tarim basin is of significance to understanding the formation of the oil and gas reservoirs in the basin.

  13. Petroleum geology of the Palo Duro Basin, Texas Panhandle

    International Nuclear Information System (INIS)

    The Palo Duro Basin, Permian Basin, Texas is an asymmetric, relatively shallow, intracratonic basin in the southern Texas Panhandle filled mostly by Mississippian, Pennsylvanian, and Permian sedimentary rocks. Although deeper and prolific prolific petroleum-producing basins adjoin it on the north (Anadarko Basin), south (Midland Basin), and east (Hardeman Basin), the Palo Duro Basin has produced remarkably small amounts of oil and gas to date. This is all the more noteworthy because the sedimentary sequence and rock types of the basin are similar to those of the adjacent basins. Analyses of the stratigraphic succession and structural configuration of the Palo Duro Basin suggest that adequate reservoir rocks, top-seals, and geologic structures are present. Most of the structures formed early enough to have trapped hydrocarbons if they were migrating in the rock column. Although additional work is under way to properly address the question of the petroleum source rocks, generation, and migration, the general absence of production in the basin may relate to an overall deficiency in hydrocarbon generation within the basin. Geologic information in this report will form part of the basis for further analysis and conclusions on hydrocarbon potential in the Palo Duro Basin

  14. Hydrogeology of the West Siberian Basin

    International Nuclear Information System (INIS)

    Nuclear fuel cycle activities of the former Soviet Union (FSU) have resulted in significant contamination of the environment in western Siberia. The radioactive releases to surface waters and the surficial environment from the Mayak site are the largest known in the world. However, they are dwarfed by the amounts of liquid wastes injected into the subsurface at Tomsk and Krasnoyarsk since the early 1960s. This paper provides the status of efforts by Pacific Northwest National Laboratory to quantify the regional hydrogeologic context for potential contaminant migration from areas in western Siberia. The West Siberian Basin is the largest platformal basin and region of low relief on earth. Ground water in the West Siberian Basin is contained in a single geologic structure (i.e., a single basin). Hydrogeologic cross sections indicate that freshwater wedges are present in both unconfined and confined aquifers (as well as in Paleozoic rocks) in the highland regions that rim the basin. The authors developed a 13-layer, finite-element computer model of the West Siberian Basin primarily based on GIS integration of data from geologic studies. The top of the hydrologic system was assumed to coincide with a water table derived from smoothed topography and surface-water occurrences; precipitation supplied the water, and the topographic gradient of the water table supplied the driving force for ground-water flow. The general directions of calculated ground-water flow suggest that (1) the major rivers act as discharge areas, with upwelling below the rivers extending down into the basement rocks; and (2) ground-water divides that penetrate the entire thickness of the model are evident between the major rivers. Their results suggest that contaminants entering the confined aquifer system may eventually migrate to the surface, discharging within major rivers, rather than remaining confined for long travel distances within the basin sediments

  15. Preliminary discussion on relationship between deep-basin gas and uranium mineralization in Ordos basin

    International Nuclear Information System (INIS)

    Deep-basin gas is a kind of non-traditional natural gas deposit. The deep-basin gas in Ordos basin is closely associated with uranium mineralization. Upper Paleozoic in the basement of the basin represents both gas-sourced and uranium-sourced beds and uranium in Paleozoic strata is easily leachable. The squeezed water (i.e. deep-bed water) formed during the diagenetic process of uranium-sourced bed was rapidly heated and pressed making the uranium solubility in it greatly increased. It was just the peak-period of gas generation in the basin, and gas pressure greatly exceeded water pressure. So, the gas made deep-bed water moved and diffused upwards along faults. Because of the complicated gas-water geochemical barrier formed by the involvement of surface water, the precipitation of uranium occurred in overlying aquifers to form uranium deposit. This paper has summarized prospecting criteria of such uranium deposit as well

  16. El 81% de los aragoneses está a favor de la utilización de energías renovables

    OpenAIRE

    Centro de Investigación y Tecnología Agroalimentaria (CITA)

    2011-01-01

    Un estudio del Centro de Investigación y Tecnología Agroalimentaria de Aragón (CITA) revela que el 81% de la población de Aragón está a favor de la utilización de energías renovables a pesar de su mayor coste. Las mujeres, los jóvenes y la población universitaria son los que se muestran más a favor de este tipo de energía y también los que prueban nuevos productos y realizan una recogida selectiva de basura mayor

  17. Corrosion in ICPP fuel storage basins

    International Nuclear Information System (INIS)

    The Idaho Chemical Processing Plant currently stores irradiated nuclear fuel in fuel storage basins. Historically, fuel has been stored for over 30 years. During the 1970's, an algae problem occurred which required higher levels of chemical treatment of the basin water to maintain visibility for fuel storage operations. This treatment led to higher levels of chlorides than seen previously which caused increased corrosion of aluminum and carbon steel, but has had little effect on the stainless steel in the basin. Corrosion measurements of select aluminum fuel storage cans, aluminum fuel storage buckets, and operational support equipment have been completed. Aluminum has exhibited good general corrosion rates, but has shown accelerated preferential attack in the form of pitting. Hot dipped zinc coated carbon steel, which has been in the basin for approximately 40 years, has shown a general corrosion rate of 4 mpy, and there is evidence of large shallow pits on the surface. A welded type 304 stainless steel corrosion coupon has shown no attack after 13 years exposure. Galvanic couples between carbon steel welded to Type 304 stainless steel occur in fuel storage yokes exposed to the basin water. These welded couples have shown galvanic attack as well as hot weld cracking and intergranular cracking, The intergranular stress corrosion cracking is attributed to crevices formed during fabrication which allowed chlorides to concentrate

  18. Satellite altimetry over large hydrological basins

    Science.gov (United States)

    Calmant, Stephane

    2015-04-01

    The use of satellite altimetry for hydrological applications, either it is basin management or hydrological modeling really started with the 21st century. Before, during two decades, the efforts were concentrated on the data processing until a precision of a few decimeters could be achieved. Today, several web sites distribute hundreds of series spread over hundeds of rivers runing in the major basins of the world. Among these, the Amazon basin has been the most widely studied. Satellite altimetry is now routinely used in this transboundary basin to predict discharges ranging over 4 orders of magnitude. In a few years, satellite altimetry should evolve dramatically. This year, we should see the launchs of Jason-3 and that of Sentinel-3A operating in SAR mode. With SAR, the accuracy and resolution of a growing number of measurements should be improved. In 2020, SWOT will provide a full coverage that will join in a unique framework all the previous and forthcoming missions. These technical and thematical evolutions will be illustrated by examples taken in the Amazon and Congo basin.

  19. Corrosion in ICPP fuel storage basins

    International Nuclear Information System (INIS)

    The Idaho Chemical Processing Plant currently stores irradiated nuclear fuel in fuel storage basins. Historically, fuel has been stored for over 30 years. During the 1970's, an algae problem occurred which required higher levels of chemical treatment of the basin water to maintain visibility for fuel storage operations. This treatment led to higher levels of chlorides than seen previously which cause increased corrosion of aluminum and carbon steel, but has had little effect on the stainless steel in the basin. Corrosion measurements of select aluminum fuel storage cans, aluminum fuel storage buckets, and operational support equipment have been completed. Aluminum has exhibited good general corrosion rates, but has shown accelerated preferential attack in the form of pitting. Hot dipped zinc coated carbon steel, which has been in the basin for approximately 40 years, has shown a general corrosion rate of 4 mpy, and there is evidence of large shallow pits on the surface. A welded Type 304 stainless steel corrosion coupon has shown no attack after 13 years exposure. Galvanic couples between carbon steel welded to Type 304 stainless steel occur in fuel storage yokes exposed to the basin water. These welded couples have shown galvanic attack as well as hot weld cracking and intergranular cracking. The intergranular stress corrosion cracking is attributed to crevices formed during fabrication which allowed chlorides to concentrate

  20. Basin analysis and modeling of the burial, thermal and maturation histories in sedimentary basins

    Energy Technology Data Exchange (ETDEWEB)

    Makhous, M.; Galushkin, Y.

    2004-11-01

    This book is devoted to the field of basin analysis, and in particular to the one- and two-dimensional modeling of the burial, thermal and maturation histories of sedimentary basins, in the context of evaluating their hydrocarbon potential. A new modeling system is elaborated in this work and applied to continental basins. Particular attention is paid to specific features of basin evolution, including the compaction of sediments deposited at a variable rate, erosion of the sedimentary strata and basement, intrusive and hydrothermal activity, thermal activation and reactivation of the basement, lateral heat exchange of multiple-aged blocks of the oceanic and continental lithospheres, the jumping of spreading axes, etc. Alternative methods are applied for the control of tectonic subsidence, isostasy and rheology, lithosphere stretching and thinning. In order to evaluate their respective contributions to the thermal history of basins, a variety of situations are modeled, including spreading jumping, the evaluation of erosion heat, its impact on thermal history and links to pre- and post-sedimentation history, intrusion activity, and the formation and degradation of cryolitic zones (permafrost) in high-latitude basins of the Northern and Southern Hemispheres. A joint analysis of heat flow transfer in the sedimentary cover and the underlying lithosphere and asthenosphere is applied to better reconstruct their thermal and maturation histories. To further enhance the model's validity, an additional powerful control tool is applied, based on the coincidence of two calculations of tectonic curve subsidence of the basement surface, obtained by two independent approaches: back-stripping and temperature-dependant density distribution in the crust. This approach is also used to refine the simulation sequence for tectonic and thermal events in the history of sedimentary basins. Contents: 1. The Geodynamic Setting and Some Geomechanical Aspects of the Initiation and

  1. Exploration in the Ombilin Intermontane Basin, West Sumatra

    Energy Technology Data Exchange (ETDEWEB)

    Koning, T. (Texaco Overseas (Nig.) Petroleum Co., Lagos (Nigeria))

    1996-01-01

    The Ombilin Basin is a Tertiary intermontane basin located within the Barisan Mountain Range of Sumatra. Oil exploration commenced in the Ombilin Basin in the early 1980s when geological mapping was carried out, a synthetic aperture radar survey was flown, and a basin-wide geophysical survey was completed. This effort led to the drilling of Sinimar No. 1 to a total depth 3020 m. Sinimar No. 1 was a historic well in Indonesia's oil industry since it was the first oil exploration well drilled in the Ombilin Basin and also the first well drilled in an intermontane basin in Indonesia. Oil, gas and condensate was tested in the well. An integrated interpretation of the well, geophysical and outcrop data indicates that despite its small areal size (30 km x 50 km), the Ombilin Basin is a deep pull-apart basin containing up to 4500 m of Tertiary sediments, ranging in age from Middle Eocene to Early Miocene. The basin currently is in an intermontane basin structural setting but it was also an intermontane basin during its Early Tertiary depositional history. During the Eocene, alluvial fans and massive debris flows were deposited on the basin margins and a large lake occupied the basin center. Fluvial deposition occurred in the basin during the Oligocene followed by deposition of marine shales, sandstones, and isolated reefs during the Miocene. Although the Ombilin Basin is located within Sumatra's magmatic arc and is partially covered by volcanics from extinct and active volcanoes, the subsurface temperature gradients of 1.62 deg. F/100 ft. recorded in Sinimar No. I and 1.47 deg F/100 ft. measured in a deep (670 m) coal exploration core hole are significantly cooler than the average subsurface temperature gradients in the Sumatra back-arc basins. Organic-rich Eocene lacustrine shales are the likely source rocks for the hydrocarbons tested in Sinimar No. 1 and the oil seeps located along the basin margins.

  2. Exploration in the Ombilin Intermontane Basin, West Sumatra

    Energy Technology Data Exchange (ETDEWEB)

    Koning, T. [Texaco Overseas (Nig.) Petroleum Co., Lagos (Nigeria)

    1996-12-31

    The Ombilin Basin is a Tertiary intermontane basin located within the Barisan Mountain Range of Sumatra. Oil exploration commenced in the Ombilin Basin in the early 1980s when geological mapping was carried out, a synthetic aperture radar survey was flown, and a basin-wide geophysical survey was completed. This effort led to the drilling of Sinimar No. 1 to a total depth 3020 m. Sinimar No. 1 was a historic well in Indonesia`s oil industry since it was the first oil exploration well drilled in the Ombilin Basin and also the first well drilled in an intermontane basin in Indonesia. Oil, gas and condensate was tested in the well. An integrated interpretation of the well, geophysical and outcrop data indicates that despite its small areal size (30 km x 50 km), the Ombilin Basin is a deep pull-apart basin containing up to 4500 m of Tertiary sediments, ranging in age from Middle Eocene to Early Miocene. The basin currently is in an intermontane basin structural setting but it was also an intermontane basin during its Early Tertiary depositional history. During the Eocene, alluvial fans and massive debris flows were deposited on the basin margins and a large lake occupied the basin center. Fluvial deposition occurred in the basin during the Oligocene followed by deposition of marine shales, sandstones, and isolated reefs during the Miocene. Although the Ombilin Basin is located within Sumatra`s magmatic arc and is partially covered by volcanics from extinct and active volcanoes, the subsurface temperature gradients of 1.62 deg. F/100 ft. recorded in Sinimar No. I and 1.47 deg F/100 ft. measured in a deep (670 m) coal exploration core hole are significantly cooler than the average subsurface temperature gradients in the Sumatra back-arc basins. Organic-rich Eocene lacustrine shales are the likely source rocks for the hydrocarbons tested in Sinimar No. 1 and the oil seeps located along the basin margins.

  3. The Impact of Individual Ability, Favorable Team Member Scores, and Student Perception of Course Importance on Student Preference of Team-Based Learning and Grading Methods

    Science.gov (United States)

    Su, Allan Yen-Lun

    2007-01-01

    This study explores the impact of individual ability and favorable team member scores on student preference of team-based learning and grading methods, and examines the moderating effects of student perception of course importance on student preference of team-based learning and grading methods. The author also investigates the relationship…

  4. Using geologic conditions and multiattribute decision analysis to determine the relative favorability of selected areas for siting a high-level radioactive waste repository

    International Nuclear Information System (INIS)

    A method is presented for determining the relative favorability of geologically complex areas for isolating high-level radioactive wastes. In applying the method to the northeastern region of the United States, seismicity and tectonic activity were the screening criteria used to divide the region into three areas of increasing seismotectonic risk. Criteria were then used to subdivide the area of lowest seismotectonic risk into six geologically distinct subareas including characteristics, surface-water and groundwater hydrology, potential human intrusion, site geometry, surface characteristics, and tectonic environment. Decision analysis was then used to identify the subareas most favorable from a geologic standpoint for further investigation, with a view to selecting a site for a repository. Three subareas (parts of northeastern Vermont, northern New Hampshire, and western Maine) were found to be the most favorable, using this method and existing data. However, because this study assessed relative geologic favorability, no conclusions should be drawn concerning the absolute suitability of individual subareas for high-level radioactive waste isolation. 34 refs., 7 figs., 20 tabs

  5. Using geologic conditions and multiattribute decision analysis to determine the relative favorability of selected areas for siting a high-level radioactive waste repository

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, W.; Edgar, D.E.; Baker, C.H.; Buehring, W.A.; Whitfield, R.G.; Van Luik, A.E.J.; Sood, M.K.; Flower, M.F.J.; Warren, M.F.; Jusko, M.J.; Peerenboom, J.P.; Bogner, J.E.

    1988-05-01

    A method is presented for determining the relative favorability of geologically complex areas for isolating high-level radioactive wastes. In applying the method to the northeastern region of the United States, seismicity and tectonic activity were the screening criteria used to divide the region into three areas of increasing seismotectonic risk. Criteria were then used to subdivide the area of lowest seismotectonic risk into six geologically distinct subareas including characteristics, surface-water and groundwater hydrology, potential human intrusion, site geometry, surface characteristics, and tectonic environment. Decision analysis was then used to identify the subareas most favorable from a geologic standpoint for further investigation, with a view to selecting a site for a repository. Three subareas (parts of northeastern Vermont, northern New Hampshire, and western Maine) were found to be the most favorable, using this method and existing data. However, because this study assessed relative geologic favorability, no conclusions should be drawn concerning the absolute suitability of individual subareas for high-level radioactive waste isolation. 34 refs., 7 figs., 20 tabs.

  6. Displacement policy favoring the walk in the towns. Actions of european towns; Politiques de deplacement favorisant la marche a pied en ville. Actions de villes europeenne

    Energy Technology Data Exchange (ETDEWEB)

    Vallar, J.P.; Wagenaar, D.

    2003-07-01

    Many towns in Europe began policies favoring the walk. By an evaluation of the actions realized, this study presents the results in four main topics: the planning, the organization, the communication and public information, the evaluation of the initiatives and the perspectives. (A.L.B.)

  7. Favorable alleles for stem water-soluble carbohydrates identified by association analysis contribute to grain weight under drought stress conditions in wheat.

    Science.gov (United States)

    Li, Weiyu; Zhang, Bin; Li, Runzhi; Chang, Xiaoping; Jing, Ruilian

    2015-01-01

    Drought is a major environmental constraint to crop distribution and productivity. Stem water-soluble carbohydrates (WSC) buffer wheat grain yield against conditions unfavorable for photosynthesis during the grain filling stage. In this study, 262 winter wheat accessions and 209 genome-wide SSR markers were collected and used to undertake association analysis based on a mixed linear model (MLM). The WSC in different internodes at three growth stages and 1000-grain weight (TGW) were investigated under four environmental regimes (well-watered, drought stress during the whole growth period, and two levels of terminal drought stress imposed by chemical desiccation under the well-watered and drought stress during the whole growth period conditions). Under diverse drought stress conditions, WSC in lower internodes showed significant positive correlations with TGW, especially at the flowering stage under well-watered conditions and at grain filling under drought stress. Sixteen novel WSC-favorable alleles were identified, and five of them contributed to significantly higher TGW. In addition, pyramiding WSC favorable alleles was not only effective for obtaining accessions with higher WSC, but also for enhancing TGW under different water regimes. During the past fifty years of wheat breeding, WSC was selected incidentally. The average number of favorable WSC alleles increased from 1.13 in the pre-1960 period to 4.41 in the post-2000 period. The results indicate a high potential for using marker-assisted selection to pyramid WSC favorable alleles in improving WSC and TGW in wheat. PMID:25768726

  8. Configuration Management Plan for K Basins

    International Nuclear Information System (INIS)

    This plan describes a configuration management program for K Basins that establishes the systems, processes, and responsibilities necessary for implementation. The K Basins configuration management plan provides the methodology to establish, upgrade, reconstitute, and maintain the technical consistency among the requirements, physical configuration, and documentation. The technical consistency afforded by this plan ensures accurate technical information necessary to achieve the mission objectives that provide for the safe, economic, and environmentally sound management of K Basins and the stored material. The configuration management program architecture presented in this plan is based on the functional model established in the DOE Standard, DOE-STD-1073-93, open-quotes Guide for Operational Configuration Management Programclose quotes

  9. Electricity, development and cooperation in mediterranean basin

    International Nuclear Information System (INIS)

    Energy consumption along the southern rim of the Mediterranean basin is increasing much more quickly than on the northern side, in accordance with the different industrialization and urbanization rates. Over the last two decades, electric power consumption has been increasing throughout the basin at a rate exceeding not only that of total energy consumption but even that of the economy itself. The various electric power development strategies the countries of the Mediterranean have developed differ widely depending on the available energy resources they have. Power distribution systems are a strategic element of co-operation in the Mediterranean basin. Though all of these strategies involve cost trade-offs between diversification of energy sources, domestic supply and environmental protection, difficulties exist that may curtail the development of these programs. 2 figs., 4 tabs

  10. An important form of basin-mountain coupling:Orogenic belt and flank basin

    Institute of Scientific and Technical Information of China (English)

    WANG Erchie

    2004-01-01

    Orogeny is always associated with the erosion and sediments carried by both transverse and longitudinal river systems. Those two river systems transport sediments into foreland or hinterland basin and flank basin. Longitudinal river systems prevail in and around the Tibetan Plateau due to the fact that they flow parallel to the strike of structures within the developing mountain belt. The flank basins surrounded the Tibetan Plateau and adjacent areas are developed in different tectonic settings, including inland,continental margin and deep ocean, most of them containing oil and natural gas. Those basins not only have longer evolution histories than foreland basins but also are more complete in their records of deposition. Coupling of orogeny and flank basin deposition also occurred widely in pre-Cenozoic time, in particular, the coupling between the Qinling orogenic belt and Songpan-Ganzi flysch flank basin is the most distinctive. The evolution of ancient latitudinal rivers derived from the Qinling orogenic belt during periods of mountain building was controlled not only by landforms but also by the lateral extrusion of the crustal fragments.

  11. Ground-water hydraulics of the deep-basin brine aquifer, Palo Duro Basin, Texas panhandle

    International Nuclear Information System (INIS)

    The Deep-Basin Brine aquifer of the Palo Duro Basin (Texas Panhandle) underlies thick Permian bedded evaporites that are being evaluated as a potential high-level nuclear waste isolation repository. Potentiometric surface maps of 5 units of the Deep-Basin Brine aquifer were drawn using drill-stem test (DST) pressure data, which were analyzed by a geostatistical technique (kriging) to smooth the large variation in the data. The potentiometric surface maps indicate that the Deep-Basin Brine aquifer could be conceptually modeled as 5 aquifer units; a Lower Permian (Wolfcamp) aquifer, upper and lower Pennsylvanian aquifers, a pre-Pennsylvanian aquifer, and a Pennsylvanian to Wolfcampian granite-wash aquifer. The hydraulic head maps indicate that ground-water flow in each of the units is west to east with a minor northerly component near the Amarillo Uplift, the northern structural boundary of the basin. The Wolfcamp potentiometric surface indicates the strongest component of northerly flow. Inferred flow direction in Pennsylvanian aquifers is easterly, and in the pre-Pennsylvanian aquifer near its pinch-out in the basin center, flow is inferred to be to the north. In the granite-wash aquifer the inferred flow direction is east across the northern edge of the basin and southeast along the Amarillo Uplift

  12. Geothermal structure of Australia's east coast basins

    Science.gov (United States)

    Danis, C. R.; O'Neill, C.

    2010-12-01

    The east coast sedimentary basins of Australia formed on an active margin of eastern Gondwana, and constitute an important hydrocarbon resource. The 1600km long Sydney-Gunnedah-Bowen Basin (SGBB) is largest east coast basin system, with thick Permian to Jurassic sedimentary successions overlying Palaeozoic basement rocks. The SGBB has been the focus of renewed geothermal exploration interest, however, the thermal state and geothermal potential of the system is largely unconstrained. Geothermal exploration programs require an accurate estimate of subsurface temperature information, in addition to favourable geology, to make informed decisions on potential targe developments. Primarily temperature information comes from downhole measurements, generally non-equilibrated, which are traditionally extrapolated to depth, however such extrapolation does not take into account variations in geological structure or thermal conductivity. Here we import deep 3D geological models into finite element conduction simulations, using the code Underworld, to calculate the deep thermal structure of the basin system. Underworld allows us to incorporate complex, detailed geological architecture models, incorporating different material properties for different layers, with variable temperature and depth-dependent properties. We adopt a fixed top boundary temperature on a variable topographic surface, and vary the bottom surface boundary condition, to converge of models which satisfy equilibrated downhole temperature measurement constraints. We find coal plays an important role in insulating sedimentary basins. Heat refracts around the coal interval and produces elevated temperatures beneath thick sediments, especially where thick coal intervals are present. This workflow has been formalized into an Underworld geothermal model library, enabling model centric computational workflows. Using the imported model architecture from the geology, data can be continuously updated and added to the

  13. Hydrogeology of the West Siberian Basin

    International Nuclear Information System (INIS)

    Nuclear fuel cycle activities of the former Soviet Union (FSU) have resulted in extensive radioactive contaminant releases to the environment in western Siberia. We are developing three-dimensional numerical models of the hydrogeology and potential contaminant migration in the West Siberian Basin. We have assumed that ground-water flow in the West Siberian Basin is topographically driven, with recharge to the basin occurring in the highlands on the west, east, and south, and internal discharge localized in numerous river valleys and lakes that ultimately discharge north to the ocean. We are modeling the regional hydrogeology as three-dimensional, steady-state, saturated flow that is recharged from above. We acquired topographic, geologic, hydrostratigraphic, hydrogeologic, and water-balance data for the West Siberian Basin and constructed a regional water table. We correlated and combined 70 different rock types derived from published descriptions of West Siberian Basin rocks into 17 rock types appropriate for assignment of hydrogeologic properties on the basis of spatial heterogeneity and constituent (i.e., sand, silt, and clay) diversity. Examination of resulting three-dimensional assemblages of rock types showed that they were consistent with published and inferred paleogeography and depositional processes. Calibrating the basin's moisture balance (i.e., recharge and discharge) to the derived water table determined plausible input parameter values for unknowns such as hydraulic conductivities. The general directions of calculated ground-water flow suggest that major rivers act as discharge areas, with upwelling below the rivers extending down into the basement rocks, and that ground-water divides that penetrate the entire thickness of the model are evident between major rivers

  14. Exploration Experience and Problem concerning Deep Basin Gas in the Ordos Basin

    Institute of Scientific and Technical Information of China (English)

    MaXinhua

    2004-01-01

    Deep basin gas (DBG) reservoirs, in view of the characteristics of their main parts containing gas, are a type of subtle stratigraphic lithologic traps. But they have different reservoir-forming principles, especially in the distribution of oil, gas and water. DBG is characterized by gas-water invertion, namely the water located above the gas; however, normal non-anticline subtle reservoirs have normal distribution of gas and water, namely the water located under the gas. The theory of DBG broke the conventional exploration idea that gas is usually found in the high part of reservoir and water is under the gas. So, it provided a wide field and a new idea for the exploration of natural gas. Recently Ben E. Law (2002), in his article entitled "Basin-centered Gas Systems", discussed global DBG systemically. He listed 72 basins or areas containing known or suspected DBG, covering North America, South America, Europe, Asia-Pacific, South Asia, Middle East and Africa. Ordos basin, the Sichuan basin and the Jungar basin in China are presented and assumed to be of very high possibility. In China more attention has been paid to the research and exploration of DBG in the past years. The symposiums on DBG were held twice, in Guangzhou in 1998 and in Xi'an in 2000 respectively. In 2002 in particular, the publication of the book named Deep Basin Gas in China by Professor Wangtao indicated that China has entered a new stage in the research on DBG. Meanwhile, it is more cheering that the exploration of DBG in the Ordos Basin has achieved remarkable success. Therefore, analyzing the exploration experiences and problems regarding the Ordos basin will promote the exploration and research of DBG in China.

  15. Processes of water rock interaction in the Turonian aquifer of Oum Er-Rabia Basin, Morocco

    Science.gov (United States)

    Ettazarini, Said

    2005-12-01

    Possible water rock interaction processes, in the Moroccan basin of Oum Er-Rabia, were discussed by a geochemical study of groundwater from the Turonian limestone aquifer, the most important water resource in the region. Different types of water according to the classification of Piper were defined. Waters have shown an evolution from dominant CHO3 Ca Mg type through mixed to SO4 Cl Ca Mg type. The use of geochemical diagrams and chemical speciation modeling method has shown that water rock interaction is mainly controlled by carbonate and anhydrite dissolution, ion exchange and reverse ion exchange processes. Water rock equilibrium conditions are favorable for the precipitation of calcite, dolomite, kaolinite and magnesian smectite.

  16. THE LIQUID PRECIPITATION ABUNDANCE OF THE PRUT BASIN IN JULY 2008

    Directory of Open Access Journals (Sweden)

    Paula R. Furtună

    2012-03-01

    Full Text Available The liquid precipitation abundance of the Prut Basin in July 2008. In the last years, the severe meteorological phenomen, Moldavia included, have increased significantly in intensity, reaching here and there certain thresholds difficult to accept a couple of years ago. This study proposes to marked the role of abundant rainfall that had caused the floods in July 2008 on the Prut river and to identify and to characterize the synoptic situation that favored large amounts of precipitation fall in the period mentioned above. The consequences of exces precipitation periods from July 2008 have led to the increased of the debit river that had produced important floods in North and North-Eastern of Romania on Prut, Siret and Tisa drowned large area of flamand and grassland destroying road infrastructure and even leading to lives lost.

  17. Geochemical characteristics of Jurassic coal and significance for the evolution of the environment, Yanqi Basin, China

    Institute of Scientific and Technical Information of China (English)

    WU Chaodong; XU Youling; GUO Zhaojie; QUAN Shujin; LI Yonglin; FENG Xue

    2006-01-01

    The Mesozoic strata of the Yanqi Basin consists of coarse debris with coal beds, characterized by the developments of coal seams of the Jurassic sediments whose main petrologic contents are glutenite, fine sandstone, mudstone, carbonaceous shale and coal. Based on the analyses of the minerals, trace elements and REEs, we try to find geochemical characteristics of the coal seam formation process. The analysis results indicate that the contents of ash and sulfur are low while the content of phosphor is comparatively high, and that the specific value of Al2O3/SiO2 is relatively high and that of (Al2O3+SiO2)/(Fe2O3 + CaO+ MgO) is near 1. All these results indicate that the coal seams are formed in the relatively deep marsh, which is favorable for the evolvement of hydrocarbon at the diagenesis stage.

  18. Megafans of the Northern Kalahari Basin

    Science.gov (United States)

    Wilkinson, M. J.; Miller, R. McG.; Eckardt, F.; Kreslavsky, M. A.

    2016-01-01

    We identify eleven megafans (partial cones of fluvial sediment, >80 km radius) in the northern Kalahari Basin, using several criteria based on VIS and IR remotely sensed data and SRTM-based surface morphology reconstructions. Two other features meet fewer criteria of the form which we class as possible megafans. The northern Kalahari megafans are located in a 1700 km arc around the southern and eastern flanks of the Angola's Bié Plateau, from northern Namibia through northwest Botswana to western Zambia. Three lie in the Owambo subbasin centered on the Etosha Pan, three in the relatively small Okavango rift depression, and five in the Upper Zambezi basin. The population includes the well-known Okavango megafan (150 km), Namibia's Cubango megafan, the largest megafan in the region (350 km long), and the largest nested group (the five major contiguous megafans on the west slopes of the upper Zambezi Valley). We use new, SRTM-based topographic roughness data to discriminate various depositional surfaces within the flat N. Kalahari landscapes. We introduce the concepts of divide megafans, derived megafans, and fan-margin rivers. Conclusions. (i) Eleven megafan cones total an area of 190,000 sq km. (ii) Different controls on megafan size operate in the three component basins: in the Okavango rift structural controls become the prime constraint on megafan length by controlling basin dimensions. Megafans in the other les constricted basins appear to conform to classic relationships fan area, slope, and feeder-basin area. (iii) Active fans occupy the Okavango rift depression with one in the Owambo basin. The rest of the population are relict but recently active fans (surfaces are relict with respect to activity by the feeder river). (iv) Avulsive behavior of the formative river-axiomatic for the evolution of megafans-has resulted in repeated rearrangements of regional drainage, with likely effects in the study area well back into the Neogene. Divide megafans comprise the

  19. Simplified vibratory characterization of alluvial basins

    CERN Document Server

    Semblat, Jean-François; Duval, Anne-Marie

    2011-01-01

    For the analysis of seismic wave amplification, modal methods are interesting tools to study the modal properties of geological structures. Modal approaches mainly lead to information on such parameters as fundamental frequencies and eigenmodes of alluvial basins. For a specific alluvial deposit in Nice (France), a simplified modal approach involving the Rayleigh method is considered. This approach assumes a set of admissible shape functions for the eigenmodes and allows a fast estimation of the fundamental frequency of the basin. The agreement between modal numerical results and experimental ones is satisfactory. The simplified modal method then appears as an efficient mean for the global vibratory characterization of geological structures towards resonance.

  20. Basins of attraction for chimera states

    Science.gov (United States)

    Martens, Erik A.; Panaggio, Mark J.; Abrams, Daniel M.

    2016-02-01

    Chimera states—curious symmetry-broken states in systems of identical coupled oscillators—typically occur only for certain initial conditions. Here we analyze their basins of attraction in a simple system comprised of two populations. Using perturbative analysis and numerical simulation we evaluate asymptotic states and associated destination maps, and demonstrate that basins form a complex twisting structure in phase space. Understanding the basins’ precise nature may help in the development of control methods to switch between chimera patterns, with possible technological and neural system applications.

  1. Formation and evolution of Turpan-Hami Basin

    International Nuclear Information System (INIS)

    By the analysis of regional stress field, the evolutionary of Tur pan-Hami Basin can be divided into three phases. The paper focuses on the analysis of stress features, types of basin, environment and thickness of deposition. (author)

  2. Ferromanganese nodules from the Central Indian Ocean Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Jauhari, P.; Pattan, J.N.

    In order to delineate a mine site for ferromanganese nodules, extensive surveys were conducted in Central Indian Ocean Basin. Mapping of the basin by multibeam swath bathymetry (Hydrosweep) has revealed many new bottom relief features...

  3. Geology of the Caloris basin, Mercury: a view from MESSENGER.

    Science.gov (United States)

    Murchie, Scott L; Watters, Thomas R; Robinson, Mark S; Head, James W; Strom, Robert G; Chapman, Clark R; Solomon, Sean C; McClintock, William E; Prockter, Louise M; Domingue, Deborah L; Blewett, David T

    2008-07-01

    The Caloris basin, the youngest known large impact basin on Mercury, is revealed in MESSENGER images to be modified by volcanism and deformation in a manner distinct from that of lunar impact basins. The morphology and spatial distribution of basin materials themselves closely match lunar counterparts. Evidence for a volcanic origin of the basin's interior plains includes embayed craters on the basin floor and diffuse deposits surrounding rimless depressions interpreted to be of pyroclastic origin. Unlike lunar maria, the volcanic plains in Caloris are higher in albedo than surrounding basin materials and lack spectral evidence for ferrous iron-bearing silicates. Tectonic landforms, contractional wrinkle ridges and extensional troughs, have distributions and age relations different from their counterparts in and around lunar basins, indicating a different stress history. PMID:18599772

  4. Basin and Range Province, Western US, USGS Grids #3

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These grid files were used to produce gravity and basin depth maps of the Basin and Range Province, western United States. The maps show gravity values and modeled...

  5. Alluvial basin statistics of the Southwest Principal Aquifers (SWPA) study.

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — SWPA_alvbsn is a vector dataset of alluvial-fill basin statistics for the Southwest United States. Statistics for each basin include physical details such as area,...

  6. SimBasin: serious gaming for integrated decision-making in the Magdalena-Cauca basin

    Science.gov (United States)

    Craven, Joanne; Angarita, Hector; Corzo, Gerald

    2016-04-01

    The Magdalena-Cauca macrobasin covers 24% of the land area of Colombia, and provides more than half of the country's economic potential. The basin is also home a large proportion of Colombia's biodiversity. These conflicting demands have led to problems in the basin, including a dramatic fall in fish populations, additional flooding (such as the severe nationwide floods caused by the La Niña phenomenon in 2011), and habitat loss. It is generally believed that the solution to these conflicts is to manage the basin in a more integrated way, and bridge the gaps between decision-makers in different sectors and scientists. To this end, inter-ministerial agreements are being formulated and a decision support system is being developed by The Nature Conservancy Colombia. To engage stakeholders in this process SimBasin, a "serious game", has been developed. It is intended to act as a catalyst for bringing stakeholders together, an illustration of the uncertainties, relationships and feedbacks in the basin, and an accessible introduction to modelling and decision support for non-experts. During the game, groups of participants are led through a 30 year future development of the basin, during which they take decisions about the development of the basin and see the impacts on four different sectors: agriculture, hydropower, flood risk, and environment. These impacts are displayed through seven indicators, which players should try to maintain above critical thresholds. To communicate the effects of uncertainty and climate variability, players see the actual value of the indicator and also a band of possible values, so they can see if their decisions have actually reduced risk or if they just "got lucky". The game works as a layer on top of a WEAP water resources model of the basin, adapted from a basin-wide model already created, so the fictional game basin is conceptually similar to the Magdalena-Cauca basin. The game is freely available online, and new applications are being

  7. New aerogeophysical study of the Eurasia Basin and Lomonosov Ridge: Implications for basin development

    DEFF Research Database (Denmark)

    Brozena, J.M.; Childers, V.A.; Lawver, L.A.;

    2003-01-01

    In 1998 and 1999, new aerogeophysical surveys of the Arctic Ocean's Eurasia Basin produced the first collocated gravity and magnetic measurements over the western half of the basin. These data increase the density and extend the coverage of the U.S. Navy acromagnetic data from the 1970s. The new...... Norwegian-Greenland Sea. With the opening of the Labrador Sea, Greenland began similar to200 km of northward movement relative to North America and eventually collided with Svalbard, Ellesmere Island, and the nascent Eurasia ocean basin. Both gravity and magnetic data sets reconstructed to times prior to...

  8. Morphometric analysis of Suketi river basin, Himachal Himalaya, India

    Indian Academy of Sciences (India)

    Anil M Pophare; Umesh S Balpande

    2014-10-01

    Suketi river basin is located in the Mandi district of Himachal Pradesh, India. It encompasses a central inter-montane valley and surrounding mountainous terrain in the Lower Himachal Himalaya. Morphometric analysis of the Suketi river basin was carried out to study its drainage characteristics and overall groundwater resource potential. The entire Suketi river basin has been divided into five sub-basins based on the catchment areas of Suketi trunk stream and its major tributaries. Quantitative assessment of each sub-basin was carried out for its linear, areal, and relief aspects. The analysis reveals that the drainage network of the entire Suketi river basin constitutes a 7th order basin. Out of five sub-basins, Kansa khad sub-basin (KKSB), Gangli khad sub-basin (GKSB) and Ratti khad sub-basin (RKSB) are 5th order subbasins. The Dadour khad sub-basin (DKSB) is 6th order sub-basin, while Suketi trunk stream sub-basin (STSSB) is a 7th order sub-basin. The entire drainage basin area reflects late youth to early mature stage of development of the fluvial geomorphic cycle, which is dominated by rain and snow fed lower order streams. It has low stream frequency (Fs) and moderate drainage density (Dd) of 2.69 km/km2. Bifurcation ratios (Rb) of various stream orders indicate that streams up to 3rd order are surging through highly dissected mountainous terrain, which facilitates high overland flow and less recharge into the subsurface resulting in low groundwater potential in the zones of 1st, 2nd, and 3rd order streams of the Suketi river basin. The circulatory ratio (Rc) of 0.65 and elongation ratio (Re) of 0.80 show elongated nature of the Suketi river basin, while infiltration number (If) of 10.66 indicates dominance of relief features and low groundwater potential in the high altitude mountainous terrain. The asymmetry factor (Af) of Suketi river basin indicates that the palaeo-tectonic tilting, at drainage basin scale, was towards the downstream right side of the

  9. K West basin isolation barrier leak rate test

    Energy Technology Data Exchange (ETDEWEB)

    Whitehurst, R.; McCracken, K.; Papenfuss, J.N.

    1994-10-31

    This document establishes the procedure for performing the acceptance test on the two isolation barriers being installed in K West basin. This acceptance test procedure shall be used to: First establish a basin water loss rate prior to installation of the two isolation barriers between the main basin and the discharge chute in K-Basin West. Second, perform an acceptance test to verify an acceptable leakage rate through the barrier seals.

  10. K West basin isolation barrier leak rate test

    International Nuclear Information System (INIS)

    This document establishes the procedure for performing the acceptance test on the two isolation barriers being installed in K West basin. This acceptance test procedure shall be used to: First establish a basin water loss rate prior to installation of the two isolation barriers between the main basin and the discharge chute in K-Basin West. Second, perform an acceptance test to verify an acceptable leakage rate through the barrier seals

  11. Hydronomics and terranomics in the Nyando basin of Western Kenya.

    OpenAIRE

    Onyango, Leah; Swallow, Brent; Meinzen-Dick, Ruth

    2005-01-01

    This paper uses the concepts of hydronomics as systems of rules that define water management and terranomics as systems of rules that define land management and explores their linkages in rainfed agriculture and irrigation areas in the Nyando basin. The upper reaches of the basin have experienced a change from large scale commercial farming to more intensive small holder farming while in the flood prone lower reaches of the basin several irrigation schemes have been set up. The basin has a co...

  12. Geologic features of Wunite Erlian basin depression and prospecting analysis on in-situ sandstone-type uranium deposit

    International Nuclear Information System (INIS)

    Wunite depression located in the east of Erlian basin is one of the five biggest depressions in Erlian basin, and its sub-sags can be classified into two types: the units in depression zone and the other ones in uplift zone. Fluvial fan sedimentary-braided river system disposed at the former one, including vertical channel deposit model and centripetal channel deposit model: fan delta-lake system disposed at the later one, including fan deltas deposit model and braid river deltas deposit model. The main structure styles of sags are dustpan single-fault, composite single-fault, and composite double-fault. It is necessary to search these faults, in that the bottom slope belt of dustpan single-fault and composite single-fault is favorable for prospecting; the Saihantala sandstone which is at the two sides of the steep hill of composite single-fault and the sags of composite double-fault formed as monoclinal stratum. The sags featured by braid river deltas and vertical channel deposit model whose Saihantala sandstone possess modest thickness, fine stratification and connectivity, are favorable for prospecting in-situ sandstone-type Uranium deposit at Wunite zone. (authors)

  13. Maturation history modeling of Sufyan Depression, northwest Muglad Basin, Sudan

    Science.gov (United States)

    Wang, Ying; Liu, Luofu; An, Fuli; Wang, Hongmei; Pang, Xiongqi

    2016-08-01

    The Sufyan Depression is located in the northwest of Muglad Basin and is considered as a favorable exploration area by both previous studies and present oil shows. In this study, 16 wells are used or referred, the burial history model was built with new seismic, logging and well data, and the thermal maturity (Ro, %) of proved AG source rocks was predicted based on heat flow calculation and EASY %Ro modeling. The results show that the present heat flow range is 36 mW/m2∼50 mW/m2 (average 39 mW/m2) in 13 wells and 15 mW/m2∼55 mW/m2 in the whole depression. Accordingly, the geothermal gradient is 20 °C/km∼26 °C/km and 12 °C/km∼30 °C/km, respectively. The paleo-heat flow has three peaks, namely AG-3 period, lower Bentiu period and Early Paleogene, with the value decreases from the first to the last, which is corresponding to the tectonic evolution history. Corresponding to the heat flow distribution feature, the AG source rocks become mature earlier and have higher present marurity in the south area. For AG-2_down and AG-3_up source rocks that are proved to be good-excellent, most of them are mature with Ro as 0.5%-1.1%. But they can only generate plentiful oil and gas to charge reservoirs in the middle and south areas where their Ro is within 0.7%-1.1%, which is consistent with the present oil shows. Besides, the oil shows from AG-2_down reservoir in the middle area of the Sufyan Depression are believed to be contributed by the underlying AG-3_up source rock or the source rocks in the south area.

  14. Integrated Worker Radiation Dose Assessment for the K Basins

    International Nuclear Information System (INIS)

    This report documents an assessment of the radiation dose workers at the K Basins are expected to receive in the process of removing spent nuclear fuel from the storage basins. The K Basins (K East and K West) are located in the Hanford 100K Area

  15. Detailed bathymetric surveys in the central Indian Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Kodagali, V.N.; KameshRaju, K.A.; Ramprasad, T.; George, P.; Jaisankar, S.

    Over 420,000 line kilometers of echo-sounding data was collected in the Central Indian Basin. This data was digitized, merged with navigation data and a detailed bathymetric map of the Basin was prepared. The Basin can be broadly classified...

  16. 100KE/KW fuel storage basin surface volumetric factors

    International Nuclear Information System (INIS)

    This Supporting Document presents calculations of surface Volumetric factors for the 100KE and 100KW Fuel Storage Basins. These factors relate water level changes to basin loss or additions of water, or the equivalent water displacement volumes of objects added to or removed from the basin

  17. The fate of evaporated water from the Ganges basin

    NARCIS (Netherlands)

    Tuinenburg, O.A.; Hutjes, R.W.A.; Kabat, P.

    2012-01-01

    This research studies river basin moisture recycling rates in order to determine the atmospheric part of the water cycle and the influence of the land surface there on. For river basins in India (Ganges and Indus), the fraction of evaporation that falls again as precipitation in the same river basin

  18. Riddled Basins of Attraction for Synchronized Type-I Intermittency

    DEFF Research Database (Denmark)

    Mancher, Martin; Nordahn, Morten; Mosekilde, Erik;

    1998-01-01

    Chaotic mortion resticted to an invariant subspace of total phase space may be associated with basins of attraction that are riddled with holes belonging to the basin of another limiting state. We study the emergence of such basins of two coupled one-dimensional maps, each exhibiting type...

  19. New Progress in Petroleum Exploration of Tarim Basin

    Institute of Scientific and Technical Information of China (English)

    Liang Digang

    1994-01-01

    @@ Basin Situation Tarim Basin located in the northwest of China, is one of the few largest basins in the world that haven't been well-explored, covering an area of 560 000km2, a little bit larger than that of France.

  20. Basin development and tectonic history of the Llanos Basin, Eastern Cordillera, and Middle Magdalena Valley, Colombia

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, M.A. [PanCanadian Petroleum, Calgary, Alberta (Canada); Addison, F.T.; Alvarez, R. [BP Exploration Ltd., Bogota (Colombia)] [and others

    1995-10-01

    The Middle Magdalena Valley, Eastern Cordillera, and Llanos basin constituted a major regional sedimentary basin from the Triassic to the middle Miocene. Basin development began during the Triassic to the earliest Cretaceous with a synrift megasequence related to the separation of North and South America in the proto-Caribbean. The synrift megasequence began with deposition in a continental environment that became paralic and shallow marine in the Early Cretaceous. Basin development continued into the Cretaceous in a back-arc setting east of the Andean subduction zone. The back-arc megasequence was dominated by shallow-marine sedimentation and produced an excellent regional source rock during the Turonian-Coniacian. Marine deposition was abruptly terminated during the early Maastrichtian due to the final accretion of the Western Cordillera.