WorldWideScience

Sample records for basic principles physiological

  1. PET/TAC: Basic principles, physiological variants and artifacts

    International Nuclear Information System (INIS)

    This presentation is about the basic principles, physiologic variants and devices that work in the PET/TAC technique. Next the conclusions obtained in the same one are presented: For a correct evaluation of the PET/TAC images with FDG is necessary the knowledge of the image acquisition technique, as well as of the physiologic distribution of the FDG, variants of the normality, benign causes of captation and more frequent devices. The introduction of this hybrid procedure allows the correct anatomical localization and identification of the deposits of FDG largely avoiding false or doubtful interpretations, but it can also originate not specific devices existent in the conventional PET. The previous knowledge of the possible devices will make possible in certain cases its elimination and in other its identification avoiding incorrect interpretations. (Author)

  2. PET/TAC: Basic principles, physiological variants and artifacts; PET/TAC: Generalidades, variantes fisiologicas y artefactos

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez V, A.M. [Especialista en Medicina Nuclear, Profa. Depto. Radiologia de la Facultad de Medicina, Universidad Complutense de Madrid, Madrid (Spain)

    2007-07-01

    This presentation is about the basic principles, physiologic variants and devices that work in the PET/TAC technique. Next the conclusions obtained in the same one are presented: For a correct evaluation of the PET/TAC images with FDG is necessary the knowledge of the image acquisition technique, as well as of the physiologic distribution of the FDG, variants of the normality, benign causes of captation and more frequent devices. The introduction of this hybrid procedure allows the correct anatomical localization and identification of the deposits of FDG largely avoiding false or doubtful interpretations, but it can also originate not specific devices existent in the conventional PET. The previous knowledge of the possible devices will make possible in certain cases its elimination and in other its identification avoiding incorrect interpretations. (Author)

  3. Basic principle of superconductivity

    OpenAIRE

    De Cao, Tian

    2007-01-01

    The basic principle of superconductivity is suggested in this paper. There have been two vital wrong suggestions on the basic principle, one is the relation between superconductivity and the Bose-Einstein condensation (BEC), and another is the relation between superconductivity and pseudogap.

  4. Basic principles of pulmonary anatomy and physiology for CT interpretation of lung diseases

    International Nuclear Information System (INIS)

    High resolution CT is now the method of choice in the diagnosis of lung diseases, especially in their early recognition. However, the radiologist must be aware of precise anatomic, pathologic and physiologic data which are observed when the patient is supine. This concept leads to a transversal analysis of lung diseases by CT, as previously proposed in the coronal and sagittal planes for conventional chest X Ray interpretation. The aim of the study is to demonstrate that these regional differences in the lung must be included in the method of chest scanning but also in the interpretation of lung diseases

  5. Homeostatis and Control-integration as basic principles in the physiology of man

    Directory of Open Access Journals (Sweden)

    P. J. Pretorius

    1977-03-01

    Full Text Available The word homeostasis, proposed by W.B. Cannon in 1929, is derived from the Greek word homois (— like, resembling, the same and stasis (— standing, static. It denotes a condition of dynamic internal stability.of a system by means of coordinated reactions. These reactions of the system compensate or neutralize any disturbing influence from outside or inside the system. These disturbing influences would otherwise change the normal structural and functional characteristics of the system. Two im­ portant aspects should be considered namely: (1 the aspect of internal stability and (2 coordinated reaction to assure stability. The idea of regulation or control and coordination in living beings is not new. The basic idea is found in Chinese, Egyptian, Hebrew and Greek literature. According to Langley several physiologists were responsible for establishing the theory of homeostasis.

  6. Emulsion Science Basic Principles

    CERN Document Server

    Leal-Calderon, Fernando; Schmitt, Véronique

    2007-01-01

    Emulsions are generally made out of two immiscible fluids like oil and water, one being dispersed in the second in the presence of surface-active compounds.They are used as intermediate or end products in a huge range of areas including the food, chemical, cosmetic, pharmaceutical, paint, and coating industries. Besides the broad domain of technological interest, emulsions are raising a variety of fundamental questions at the frontier between physics and chemistry. This book aims to give an overview of the most recent advances in emulsion science. The basic principles, covering aspects of emulsions from their preparation to their destruction, are presented in close relation to both the fundamental physics and the applications of these materials. The book is intended to help scientists and engineers in formulating new materials by giving them the basics of emulsion science.

  7. Lymph node imaging: Basic principles

    International Nuclear Information System (INIS)

    Lymph nodes are involved in a wide variety of diseases, particularly in cancer. In the latter, precise nodal staging is essential to guide therapeutic options and to determine prognosis. For long, imaging of the lymphatic system has been limited to lymph vessel,especially via the exclusive use of conventional lymphography, at the expense of invasive procedures and patient's discomfort. Three main technical advances, however, have recently completed the clinical armamentarium for lymph node imaging: first, the refinement of cross sectional imaging, i.e. CT and MRI, combined or not with dedicated contrast agents, has progressively replaced conventional lymphography in oncology situations; second, the development of intra-operative sentinel node mapping has profoundly modified the diagnostic and therapeutic procedures in several cancer situations, mostly melanoma and breast cancer; finally, the increased availability of functional imaging, especially through the use of FDG-PET, has greatly contributed to the accuracy improvement of nodal metastases identification. The aim of this review will thus be to briefly review the anatomy and physiology of the lymphatic systems and to overview the basic principles of up-to-date lymph node imaging

  8. Basic safety principles: Lessons learned

    International Nuclear Information System (INIS)

    The presentation reviews the following issues: basic safety principles and lessons learned; some conclusions from the Kemeny report on the accident at TMI; some recommendations from the Kemeny report on the accident at TMI; conclusions and recommendations from the Rogovin report on the accident on TMI; instrumentation deficiencies (from Rogovin report)

  9. Thermionics basic principles of electronics

    CERN Document Server

    Jenkins, J; Ashhurst, W

    2013-01-01

    Basic Principles of Electronics, Volume I : Thermionics serves as a textbook for students in physics. It focuses on thermionic devices. The book covers topics on electron dynamics, electron emission, and the themionic vacuum diode and triode. Power amplifiers, oscillators, and electronic measuring equipment are studied as well. The text will be of great use to physics and electronics students, and inventors.

  10. Positron emission tomography. Basic principles

    International Nuclear Information System (INIS)

    The basic principles of positron emission tomography (PET) technique are reviewed. lt allows to obtain functional images from gamma rays produced by annihilation of a positron, a positive beta particle. This paper analyzes positron emitters production in a cyclotron, its general mechanisms, and the various detection systems. The most important clinical applications are also mentioned, related to oncological uses of fluor-l8-deoxyglucose

  11. Basic principles of electronics thermionics

    CERN Document Server

    Jenkins, J

    2013-01-01

    Basic Principles of Electronics, Volume I: Thermionics covers topics related to thermionic devices. The book starts by providing a physical background about electronics, including structure of matter, ionic, chemical and covalent combination, crystalline structure, conductors and insulators, and thermionic emission. The text then discusses electron dynamics; the characteristics and properties of electrons in solids; electron emission; and thermionic emission in a vacuum diode or triode. The development of the vacuum triode; gas-filled valves; and power amplifiers are also considered. The book

  12. Electrodynamics basics and duality principle

    OpenAIRE

    Ivanitckiy, A. M.

    2014-01-01

    The given report proposes general and consistent statement of the classical electrodynamics basis using axiomatic and duality principles for its construct. Vector algebra and vector analysis are created by the application of the duality principle. The last fact allows formulating Maxwell equations in strictly symmetric form. It means the statement of electrodynamics postulates (axioms) under a principle of duality. Electrodynamics basis construction begins immediately using its postulates for...

  13. Basic principles of concrete structures

    CERN Document Server

    Gu, Xianglin; Zhou, Yong

    2016-01-01

    Based on the latest version of designing codes both for buildings and bridges (GB50010-2010 and JTG D62-2004), this book starts from steel and concrete materials, whose properties are very important to the mechanical behavior of concrete structural members. Step by step, analysis of reinforced and prestressed concrete members under basic loading types (tension, compression, flexure, shearing and torsion) and environmental actions are introduced. The characteristic of the book that distinguishes it from other textbooks on concrete structures is that more emphasis has been laid on the basic theories of reinforced concrete and the application of the basic theories in design of new structures and analysis of existing structures. Examples and problems in each chapter are carefully designed to cover every important knowledge point. As a basic course for undergraduates majoring in civil engineering, this course is different from either the previously learnt mechanics courses or the design courses to be learnt. Compa...

  14. Basic photovoltaic principles and methods

    Energy Technology Data Exchange (ETDEWEB)

    Hersch, P.; Zweibel, K.

    1982-02-01

    This book presents a nonmathematical explanation of the theory and design of photovoltaic (PV) solar cells and systems. The basic elements of PV are introduced: the photovoltaic effect, physical aspects of solar cell efficiency, the typical single-crystal silicon solar cell, advances in single-crystal silicon solar cells. This is followed by the designs of systems constructed from individual cells, including possible constructions for putting cells together and the equipment needed for a practical producer of electrical energy. The future of PV is then discussed. (LEW)

  15. Phase equilibria basic principles, applications, experimental techniques

    CERN Document Server

    Reisman, Arnold

    2013-01-01

    Phase Equilibria: Basic Principles, Applications, Experimental Techniques presents an analytical treatment in the study of the theories and principles of phase equilibria. The book is organized to afford a deep and thorough understanding of such subjects as the method of species model systems; condensed phase-vapor phase equilibria and vapor transport reactions; zone refining techniques; and nonstoichiometry. Physicists, physical chemists, engineers, and materials scientists will find the book a good reference material.

  16. Basic Principles of Anodic Stripping Voltammetry (ASV)

    OpenAIRE

    2012-01-01

    In this interactive exercise, the basic principles of Anodic Stripping Voltammetry are shown. Each step of the voltammetric process is described using simulated animations. This activity illustrates what takes place in the voltammetric cell when this technique is applied to the determination of cadmium as well as to the simultaneous determination of copper and cadmium.

  17. Behavior Modification: Basic Principles. Third Edition

    Science.gov (United States)

    Lee, David L.; Axelrod, Saul

    2005-01-01

    This classic book presents the basic principles of behavior emphasizing the use of preventive techniques as well as consequences naturally available in the home, business, or school environment to change important behaviors. This book, and its companion piece, "Measurement of Behavior," represents more than 30 years of research and strategies in…

  18. Basic principles simulators - concept training simulators

    International Nuclear Information System (INIS)

    Basic Principles Simulators have the purpose of teaching general concepts, demonstrating and displaying the fundamental physical processes of a plant. They are used to illustrate theory to students and also to provide a preliminary training to the operators, to aquaint them with the basic dynamic interactions of the various systems during the normal operation of a plant, and to show the consequences of the most important and common transients and malfunctions. Basic principles simulators may vary in size from small desk cabinets to large panels. They represent with a certain detail the nuclear and thermohydraulic part of the plant. The availability of video displays allows to present detailed information about process parameters which are not shown on the control panels. In general the overall plant behaviour is represented well. Limitations are mostly found in the areas of logic and control. (orig./HP)

  19. Basic principles of experimental animals welfare protection

    OpenAIRE

    Vučinić Marijana

    2007-01-01

    Ethical considerations of animal protection and welfare require that the use of experimental animals is limited as much as possible. Animal experiments should only be performed when no alternative is available and when the benefit of the experiment outweighs the suffering of the animal. This review paper describes the basic principles for the ethical use of experimental animals. These are: "Three Rs rule" (replacement, reduction and refinement), "five fr...

  20. Basic principles of radiation protection in Canada

    International Nuclear Information System (INIS)

    The major goal of radiation protection in Canada is to ensure that individuals are adequately protected against the harm that might arise from unwarranted exposure to ionizing radiation. This report deals with the basic principles and organizations involved in protection against ionizing radiation. Three basic principles of radiation protection are: 1) that no practice shall be adopted unless its introduction produces a positive net benefit for society, 2) that all exposures shall be kept as low as reasonably achievable, relevant economic and social factors being taken into account, and 3) that doses to individuals should not exceed specified annual limits. The limit for radiation workers is currently 50 mSv per year, and exposures of the general public should not exceed a small fraction of that of radiation workers. Other specific areas in radiation protection which have received considerable attention in Canada include limitations on collective dose (the sum of the individual doses for all exposed individuals), exemption rules for extremely small radiation doses or amounts of radioactive materials, occupational hazards in uranium mining, and special rules for protection of the foetus in pregnant female radiation workers. Implementation of radiation protection principles in Canada devolves upon the Atomic Energy Control Board, the Department of National Health and Welfare, provincial authorities, licensees and radiation workers. A brief description is given of the roles of each of these groups

  1. Control functions in MFM. Basic principles

    International Nuclear Information System (INIS)

    Multilevel Flow Modeling (MFM) has been proposed as a tool for representing goals and functions of complex industrial plants and suggested as a basis for reasoning about control situations. Lind presents an introduction to MFM but do not describe how control functions are used in the modeling. The purpose of the present paper is to serve as a companion paper to this introduction by explaining the basic principles used in MFM for representation of control functions. A theoretical foundation for modeling control functions is presented and modeling examples are given for illustration. (author)

  2. Basic principles of experimental animals welfare protection

    Directory of Open Access Journals (Sweden)

    Vučinić Marijana

    2007-01-01

    Full Text Available Ethical considerations of animal protection and welfare require that the use of experimental animals is limited as much as possible. Animal experiments should only be performed when no alternative is available and when the benefit of the experiment outweighs the suffering of the animal. This review paper describes the basic principles for the ethical use of experimental animals. These are: "Three Rs rule" (replacement, reduction and refinement, "five freedoms" for animals and "Solna principles". "Replacement" means the substitution for conscious living higher animals of insentient material. "Reduction" means reduction in the numbers of animals used to obtain information of a given amount and precision. "Refinement" means any decrease in the incidence or severity of inhumane procedures applied to those animals which still have to be used. The "five freedoms" are: freedom from hunger and thirst, freedom from adverse environmental impacts, freedom from disease and injury, freedom to exhibit normal behavior and freedom from adverse mental states. "Solna principles" state that tests for regulatory purposes need to reflect the following: biological Relevance (meaningfulness and usefulness of a test for a particular purpose, Reliability (reproducibility of results within and between laboratories, and Regulatory acceptability (suitability of a test for risk assessment purposes (human health /environment.

  3. Basic principles of maximizing dental office productivity.

    Science.gov (United States)

    Mamoun, John

    2012-01-01

    To maximize office productivity, dentists should focus on performing tasks that only they can perform and not spend office hours performing tasks that can be delegated to non-dentist personnel. An important element of maximizing productivity is to arrange the schedule so that multiple patients are seated simultaneously in different operatories. Doing so allows the dentist to work on one patient in one operatory without needing to wait for local anesthetic to take effect on another patient in another operatory, or for assistants to perform tasks (such as cleaning up, taking radiographs, performing prophylaxis, or transporting and preparing equipment and supplies) in other operatories. Another way to improve productivity is to structure procedures so that fewer steps are needed to set up and implement them. In addition, during procedures, four-handed dental passing methods can be used to provide the dentist with supplies or equipment when needed. This article reviews basic principles of maximizing dental office productivity, based on the author's observations of business logistics used by various dental offices. PMID:22414506

  4. Basic principles and mechanisms of selective oil agglomeration

    Energy Technology Data Exchange (ETDEWEB)

    Wheelock, T.D.; Drzymala, J.; Allen, R.W.; Hu, Y.C.; Tyson, D.; Ziaoping, Qiu, Lessa, A.

    1990-04-01

    The overall objective is to determine the basic principles and mechanisms which underlie a number of selective oil agglomeration processes that have been proposed for beneficiating fine-size coal. An understanding of the basic principles and mechanisms will greatly facilitate technical development and application of such processes to various types of coal. 5 refs., 16 figs., 2 tabs.

  5. Basic Concepts and Principles of Marketing.

    Science.gov (United States)

    Beder, Hal

    1986-01-01

    Presents an overview of marketing concepts and principles. These include (1) organizational objectives, (2) exchange, (3) value, (4) market segmentation, (5) market position, (6) consumer analysis, (7) product, (8) promotion, (9) place, and (10) price. (CH)

  6. Irrigation water management: Basic principles and applications

    OpenAIRE

    Ella, Victor B.

    2007-01-01

    This presentation defines the term, irrigation, as well as explains the common methods of irrigation in attempt to define the fundamental principles needed to wisely design an irrigation system. It outlines a typical drip irrigation set-up, and discusses management of an irrigation system, including water volume application suggestions.

  7. Basic Principles in Holistic Technology Education.

    Science.gov (United States)

    Seemann, Kurt

    2003-01-01

    Outlines principles for holistic technology education by examining the following: (1) knowing and understanding through practical engagement with technology; (2) dialectics and praxis; and (3) the work of Dewey, Hegel, Feuerbach, and Marx. Identifies four interconnected factors: humans, applied setting, environment, and tools. (Contains 20…

  8. Basic Principles of Forest Fuel Reduction Treatments

    OpenAIRE

    Agee, James K; Skinner, Carl N

    2005-01-01

    Successful fire exclusion in the 20th century has created severe fire problems across the West. Not every forest is at risk of uncharacteristically severe wildfire, but drier forests are in need of active management to mitigate fire hazard. We summarize a set of simple principles important to address in fuel reduction treatments: reduction of surface fuels, increasing the height to live crown, decreasing crown density, and retaining large trees of fire-resistant species. Thinning and prescrib...

  9. Basic principles of chemistry and physical chemistry

    International Nuclear Information System (INIS)

    A course designed to provide communications between the designer of a system such as a mechanical engineer or a physicist and the material scientist such as a chemist or chemical engineer is presented. The topics discussed are stoichiometric principles, behavior of ideal gases, vapor pressure, humidity and saturation, solubility of gases in liquids, diffusion of gases, chemical reaction kinetics, and application of concepts to compatibility problems. The appendix provides problems to be used in conjunction with TV lectures

  10. Basic principles for regulating nuclear activities

    International Nuclear Information System (INIS)

    The AECB has developed as its mission statement: 'To ensure that the use of nuclear energy in Canada does not pose undue risk to health, safety, security and the environment'. This report proposes eleven qualitative principles for regulating nuclear activities whose achievement would satisfy the broad policy enunciated in the statement. They would further provide a basis for the specific regulatory requirements expressed by the AECB in its Regulations and other documents. They would thus represent a connecting link between the policy enunciated in the mission statement and the requirements. The proposed principles are largely concerned with how the allowable risk should be set for members of the public, for industry workers, for society as a whole, and for the environment. In making these recommendations the risks from normal operation of the licensed facility and those from a possible serious accident are considered separately. The distribution of risk between geographic communities and between generations is also addressed in the proposed principles. These are listed in the final section of the report. 23 refs

  11. Antioxidants: Basic principles, emerging concepts, and problems

    Directory of Open Access Journals (Sweden)

    Etsuo Niki

    2014-06-01

    Full Text Available The radical scavenging antioxidants play an essential role in the maintenance of health and prevention of diseases, and a thorough understanding of the action and capacity of antioxidants is critically important. Despite the assumption that antioxidants must exert beneficial effects against oxidative stress, many large-scale randomized controlled trials gave inconsistent and disappointing results on the prevention of chronic diseases. It is now generally accepted that there is no evidence to support the use of non-discriminative antioxidant supplements for prevention of diseases. On the other hand, recent data show that antioxidants may be effective in the prevention and/or treatment of diseases when the right antioxidant is given to the right subject at the right time for the right duration. Now it is accepted that reactive oxygen species (ROS act as physiologically important signaling messengers as well as deleterious agents. The signaling ROS are produced in a subtly regulated manner, while many deleterious ROS are produced and react randomly. Free radical-mediated lipid peroxidation products which, in contrast to enzymatic oxidation products, are produced by non-specific mechanisms cause oxidative damage, but may also induce adaptive response to enhance the expression of antioxidant enzymes and compounds. This has raised a question if removal of too many ROS by supplementation of antioxidants may upset the cell signaling pathways and actually increase the risk of chronic diseases. However, it is unlikely that antioxidants impair physiologically essential signaling pathways.

  12. Basic principles for occupational radiation monitoring

    International Nuclear Information System (INIS)

    This Safety Guide sets forth the objectives of an adequate strategy for monitoring internal and external radiation exposures of workers. It covers individual monitoring, and workplace monitoring to the extent required for assessment and control of individual radiation doses. The responsibilities of authorities for organizing the monitoring of radiation workers are discussed, and brief descriptions are given of the rules governing the implementation of monitoring methods. The general principles to be considered in selecting instrumentation and appropriate monitoring techniques are described, as well as calibrating techniques, methods of record keeping and related aspects

  13. Basic principles of applied nuclear techniques

    International Nuclear Information System (INIS)

    The technological applications of radioactive isotopes and radiation in South Africa have grown steadily since the first consignment of man-made radioisotopes reached this country in 1948. By the end of 1975 there were 412 authorised non-medical organisations (327 industries) using hundreds of sealed sources as well as their fair share of the thousands of radioisotope consignments, annually either imported or produced locally (mainly for medical purposes). Consequently, it is necessary for South African technologists to understand the principles of radioactivity in order to appreciate the industrial applications of nuclear techniques

  14. Basic biomechanic principles of knee instability.

    Science.gov (United States)

    Zlotnicki, Jason P; Naendrup, Jan-Hendrik; Ferrer, Gerald A; Debski, Richard E

    2016-06-01

    Motion at the knee joint is a complex mechanical phenomenon. Stability is provided by a combination of static and dynamic structures that work in concert to prevent excessive movement or instability that is inherent in various knee injuries. The anterior cruciate ligament (ACL) is a main stabilizer of the knee, providing both translational and rotatory constraint. Despite the high volume of research directed at native ACL function, pathogenesis and surgical reconstruction of this structure, a gold standard for objective quantification of injury and subsequent repair, has not been demonstrated. Furthermore, recent studies have suggested that novel anatomic structures may play a significant role in knee stability. The use of biomechanical principles and testing techniques provides essential objective/quantitative information on the function of bone, ligaments, joint capsule, and other contributing soft tissues in response to various loading conditions. This review discusses the principles of biomechanics in relation to knee stability, with a focus on the objective quantification of knee stability, the individual contributions of specific knee structures to stability, and the most recent technological advances in the biomechanical evaluation of the knee joint. PMID:27007474

  15. The Basic Principle of the Near-Field Superlens

    Science.gov (United States)

    Kim, Kyoungsik

    To overcome the diffraction limit in the optical imaging, the superlens with superresolution are developed using negative index materials. In this part, the basic principle of the near-field superlens is explained in details.

  16. Physiology of Women's Sexual Function: Basic Knowledge and New Findings

    DEFF Research Database (Denmark)

    Salonia, Andrea; Giraldi, Annamaria; Chivers, Meredith L;

    2010-01-01

    research on normal physiology of women's sexual function is needed in order to expand and "translate" current knowledge into the pathophysiological clinical setting. This manuscript encompasses data presented at the 3rd International Consultation on Sexual Medicine in Paris, France, July 10-13, 2009....... Salonia A, Giraldi A, Chivers ML, Georgiadis JR, Levin R, Maravilla KR, and McCarthy MM. Physiology of women's sexual function: Basic knowledge and new findings. J Sex Med 2010;7:2637-2660....

  17. [The history of anesthesia apparatus: basic principles].

    Science.gov (United States)

    Wawersik, J

    1982-10-01

    The beginnings of modern anesthetic equipment date back to Morton's inhalation flagon in 1846. The numerous devices developed and introduced subsequently can be divided into four groups: 1. Simple ether and chloroform masks for open inhalation anesthesia, from Simpson (1847) to Brown (1928). 2. Vapour inhalators according to the "draw over" principle of Snow (1847) up to the Oxford vaporizer (1941). 3. Closed or half-closed inhalation equipment for ether or chloroform with to and fro breathing, from Clover (1877) to Ombredanne (1908). 4. Equipment for anaesthesia with nitrous oxide. From 1868 onwards this led to the incorporation of gas bottles in anaesthetic equipment and between 1885 and 1890 to the construction of mixing-valves for nitrous oxide and oxygen. In addition, reducing valves, flow meters and vaporizers were developed. The first anaesthetic apparatus with circle system and CO2-absorber was constructed in 1925 by the Dräger factory in Lübeck. Sudeck and Schmidt introduced this technique of anaesthesia in the university hospital of Hamburg-Eppendorf between 1920 and 1925. PMID:6758628

  18. Application of Basic Principles for Intervention

    International Nuclear Information System (INIS)

    The paper deals with the basic terms which are within scope of activities of the expert group for risk analysis and assessment of potential consequences of a nuclear accident. The expert group is a part of the Technical Support Center which is going to be established within a new croatian national emergency response plan as the Lead Technical Agency in case of a nuclear emergency. Terms such as protective measures (urgent and long-term), intervention levels (generic and operational), projected and avertable doses are considered. Potential accident in the Krsko NPP, as an example for implementation of mentioned terms, is analyzed and a rapid approach for assessment in pretective measures which would be taken is applied. It is emphasized that rapid methods are characterized by a high degree of uncertainty. It is concluded that the time factor remains the most critical one in the entire accident response process. In order to optimize the time necessary for decision making, implementation and surveillance of protective measures, a set of requirements are pointed out. (author)

  19. Basic principles governing the design of magnetic switches

    International Nuclear Information System (INIS)

    The idea of using saturable reactors as the basis of high power pulse generators is not a new concept, but there have been few recent applications of this technology. Here the principle of magnetic pulse generation is briefly described and some of the basic guidelines used to design these circuits are discussed. A demonstration of the principles by a small scale pulse amplifier is presented, and finally there is an extrapolation to a large scale system

  20. Squids: principles and basic applications in experimental physics

    International Nuclear Information System (INIS)

    The basic principles and the description of the technical aspects of SQUIDs (Superconducting Quantum Interference Devices) are described. The applications of SQUIDs in experimental researches and low temperature physics experiments are given. The concepts of fluxoid quantization in a superconductor and Josephson tunnelling are reviewed. The principles, the operation, the noise and the different configurations of r.f. and direct current bias SQUIDs are summarized. The principal characteristics of several SQUIDs are reported

  1. Sustainable Economic Development: The Main Principles and the Basic Equation

    OpenAIRE

    DMIRTY CHISTILIN

    2010-01-01

    This work offers system and information content of the following economic categories: development, sustainable economic development. The author has formulated the fundamental principles of sustainable development: the principle of minimum resource dissipation and the equation of self-organization, the law of conserving the economic potential of a social system. The basic equation of development has been formulated. The model of sustainable development is viewed on the basis of the equation.

  2. Basic principles and developments of the radioisotope powered voltaic batteries

    International Nuclear Information System (INIS)

    The basic principles and some kinds of voltaic effect type radioisotope batteries are reviewed. This paper is focused on the micro-batteries based on radio-voltaic effect, which are widely used in micro-electromechanical systems (MEMs) and cardiac pacemakers. The prospects of such radio-voltaic isotope batteries are also reported. (authors)

  3. Theory of asymptotic operation. A summary of basic principles

    OpenAIRE

    Tkachov, Fyodor V.

    1997-01-01

    This summary of several talks given in 1990-1993 discusses the problem of asymptotic expansions of multiloop Feynman diagrams in masses and external momenta - a central problem in perturbative quantum field theory. Basic principles of the theory of asymptotic operation -- the most powerful tool for that purpose -- are discussed. Its connection with the conventional methods is explained (the BPHZ theory, the method of leading logarithmic approximation etc.). The problem of non-euclidean asympt...

  4. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    OpenAIRE

    Ali Nouri

    2016-01-01

    The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an inte...

  5. Basic Theoretical Principles Pertaining to Thermal Protection of Oil Transformer

    Directory of Open Access Journals (Sweden)

    O. G. Shirokov

    2008-01-01

    Full Text Available The paper contains formulation of basic theoretical principles pertaining to thermal protection of an oil transformer in accordance with classical theory of relay protection and theory of diagnostics with the purpose of unification of terminological and analytical information which is presently available in respect of this problem. Classification of abnormal thermal modes of an oil transformer and also algorithms and methods for operation of diagnostic thermal protection of a transformer have been proposed.

  6. A Review of Some Basic Principles in Fishpond Management

    OpenAIRE

    J.F.N. Abowei; C.C. Tawari; E.N. Ezekiel

    2011-01-01

    A review of some basic principles in fishpond management was reviewed to educate fish culturist, private and public sector to effectively manage culture fisheries. Successful pond management requires more than just stocking fish. It is also important to maintain the proper environmental conditions, to monitor fish harvest and growth, check for successful fish reproduction, and to keep out unwanted fish. This is the science of fish management, the solid basis for ensuring good fishing. Good fi...

  7. Basic safety principles of KLT-40C reactor plants

    International Nuclear Information System (INIS)

    The KLT-40 NSSS has been developed for a floating power block of a nuclear heat and power station on the basis of ice-breaker-type NSSS (Nuclear Steam Supply System) with application of shipbuilding technologies. Basic reactor plant components are pressurised water reactor, once-through coil-type steam generator, primary coolant pump, emergency protection rod drive mechanisms of compensate group-electromechanical type. Basic RP components are incorporated in a compact steam generating block which is arranged within metal-water shielding tank's caissons. Domestic regulatory documents on safety were used for the NSSS design. IAEA recommendations were also taken into account. Implementation of basic safety principles adopted presently for nuclear power allowed application of the KLT-40C plant for a floating power unit of a nuclear co-generation station. (author)

  8. The Basic Unit System concept and The Principle of Synergy

    CERN Document Server

    Paternina, E

    1999-01-01

    The purpose of this paper is to present a new proposal to both dualistic and holistic paradigm, by introducing a complex basic unit system mathematical concept in which the quantitative and the qualitative aspects of reality commingle in a unit, and by presenting a new principle, the principle of synergy, we have then a new framework in which the opposites can become complementary. The purpose of the Bus is to establish a complex mathematical unit concept based on Euler relation from which reality, physical reality can be treated and interpreted, starting from more basic principles or just from a unified theoretical point of view. The exact simple pendulum formula and the well-known Schodinger Wave Equation will be the starting point. This approach will mean a departure from the normal evolution of physical western science had taken, but its main advantage will not only be a synthesis of that science but also a unification that will permit validate those great achievements of figures like Galileo, Newton, Amp...

  9. The benefits of basic research: advances in reproductive physiology.

    Science.gov (United States)

    1995-06-01

    At the Population Council's Center for Biomedical Research basic research is being conducted on the reproductive system with a view to develop new contraceptive and reproductive health technologies. Research in the Reproductive Physiology Program at the Center is carried out by reproductive endocrinologists, molecular biologists, and biochemists working in eight laboratories. In several of the laboratories the function of hormones that regulate spermatogenesis is studied. Scientists in Milan Bagchi's laboratory have developed a model system, composed of cellular components in a test tube, that allows them to study the full sequence of events involved in signal transduction. In James Catterall's laboratory, scientists study how androgens regulate sexual development at the molecular level. The steroid hormones cortisol and corticosterone play critical roles in mammalian fetal development. Scientists in several laboratories study the function of two specialized testicular cells: the Leydig and Sertoli cells. The Leydig cell synthesizes and secretes testosterone, an androgen that regulates spermatogenesis. The Sertoli cell maintains the environment in which spermatogenesis occurs. Researchers in Glen Gunsalus's laboratory study an androgen-binding protein secreted by the Sertoli cell. In collaboration with scientists at the Shanghai Research Center of Biotechnology, they used advanced genetic techniques to create a biologically active form of the protein in silk worm larvae. Scientists in Patricia Morris's laboratory recently identified molecular signals that control the interactions between developing sperm and Sertoli and Leydig cells. In the laboratory of David Phillips, scientists are investigating how the HIV virus penetrates the outer layer of cells in the genital tract and infects underlying cells. In 1994 a vaginally applied microbicide was developed that may inhibit infection by sexually transmitted diseases including HIV. Applications of basic research such

  10. Basic didactic principles in the study of mathematical concepts

    Directory of Open Access Journals (Sweden)

    Testоv Vladimir

    2016-01-01

    Full Text Available The problem of understanding in the study of basic mathematical concepts in mathematics education has exacerbated during recent years. This is largely due to the fact that the style of thinking of pupils and students thanks to the intensive use of the Web becomes figurative and emotional, less inclined to abstract constructions. Fragments-clip thinking has become more common for most of students. The article deals with the didactic principles to be used in the study of mathematical concepts, which will contribute to achieving understanding.

  11. An Embalse nuclear power plant basic principles simulator

    International Nuclear Information System (INIS)

    A nuclear power plant basic principles simulator is a package of programs that numerically solve the dynamic equations of the simulated plant. This kind of tools is mainly used in the first step of training of operational personnel, to allow mental representation of physical phenomena governing the plant. They are also used for students or professional training, and experienced operators can also improve there performance under abnormal operation situations using the simulator. For the Embalse nuclear power plant, mainly the thermohydraulic behaviour, is simulated. The mathematical model was adapted from MANUVR, a code developed at the Electric Systems and Control Department of the National Atomic Energy Commission (CNEA). (Author)

  12. Basic principles and mechanisms of selective oil agglomeration

    Energy Technology Data Exchange (ETDEWEB)

    Wheelock, T.D.

    1994-07-01

    The overall objective of this work is to determine the important principles and basic mechanisms which underlie various selective oil agglomeration processes for beneficiating fine-size coal in order to facilitate the technical development and application of such processes to various types of coal. The recent work described herein has involved a more detailed study of the effects of mild oxidation on the surface properties of different types of coal and the relationship between the agglomerability of oxidized coals and their surface properties. In addition, the work has involved developing more effective means for separating coal and pyrite by finding and applying selective depressants for pyrite.

  13. Basics, principles, techniques and modern methods in paediatric ultrasonography

    Energy Technology Data Exchange (ETDEWEB)

    Riccabona, Michael, E-mail: michael.riccabona@klinikum-graz.at

    2014-09-15

    Ultrasonography (US) is the mainstay of paediatric Radiology. This review aims at revisiting basic US principles, to list specific needs throughout childhood, and to discuss the application of new and modern US methods. The various sections elude to basic US physics, technical requisites and tips for handling, diagnostically valuable applications of modern techniques, and how to properly address hazards, risks and limitations. In conclusion, US holds vast potential throughout childhood in almost all body regions and many childhood specific queries – helping to reduce the need for or to optimize more invasive or irradiating imaging. Make the most of US and offerings a dedicated paediatric US service throughout the day, the week and the year thus is and will stay a major task of Paediatric Radiology.

  14. [Physiological basics of sport activity of professional football players].

    Science.gov (United States)

    Shaljyan, A; Nebogova, K; Grigoryan, S

    2011-10-01

    Maintenance of motor activity by autonomic nervous system is adjusted, mainly, by congenital reflexes. But alongside with inborn reactions to muscular work at formation of motor skill the specific vegetative components are formed to the given kind of sport activity. The aim of our research was revealing those physiological features which are characteristic for an organism of the high skilled sportsmen, with large experience of training and competitive activity. At tested football players have been measured some parameters of external respiration and cardiovascular system. In our investigation it is shown, that programming of the same productivity of work and the same effect are achieved by unequal vegetative support and a different combination of separate components of the general vegetative reaction. Definition and a due estimation of these intermediate parameters in conditions of rest and at physical loading enables objective judgement about a functional condition of the sportsman, about weak parts in system of maintenance of a homeostasis of an organism and directions of accomplish the functioning of the basic effectors. PMID:22155808

  15. Self-organization: the basic principle of neural functions.

    Science.gov (United States)

    Szentágothai, J

    1993-06-01

    Recent neurophysiological observations are giving rise to the expectation that in the near future genuine biological experiments may contribute more than will premature speculations to the understanding of global and cognitive functions. The classical reflex principle--as the basis of neural functions--has to yield to new ideas, like autopoiesis and/or self-organization, as the basic paradigm in the framework of which the essence of the neural can be better understood. Neural activity starts in the very earliest stages of development well before receptors and afferent input become functional. Under suitable conditions, both in nervous tissue cultures and in embryonic tissue recombination experiments, the conditions of such initial autopoietic activity can be studied. This paper tries to generalize this elementary concept for various neural centers, notably for the spinal segmental apparatus and the cerebral cortex. PMID:8236059

  16. Expert systems - basic principles and possible applications in nuclear energy

    International Nuclear Information System (INIS)

    One of the primary goals of the application of mathematical methods and computational techniques in reactor physics is the effective and accurate solution of the neutron diffusion equation under various conditions. To reach this goal still requires much skill, experience, knowledge and imagination as can be seen from various contributions at this and other conferences. Experts are necessary. Will expert systems replace them. We shall discuss this question by describing the basic principles of problem solving by expert systems as compared to problem solving by mathematical and computational methods. From this we shall identify areas of possible applications of the new techniques in nuclear energy and develop some thoughts on present limitations. As a result we conclude that expert systems will not be able to replace experts as long as the experts use the systems to improve their own expertise

  17. Basic principles of aggressive rehabilitation after anterior cruciate ligament reconstruction

    Directory of Open Access Journals (Sweden)

    Dubljanin-Raspopović Emilija

    2005-01-01

    Full Text Available Rehabilitation after ACL (anterior cruciate ligament reconstruction has drastically changed over the last decade, with the adoption of a more aggressive approach, right from the first day after surgery. Progress in the effectiveness of rehabilitation is based on improvements in operative techniques, as well as on the encouraging results of histological studies regarding graft healing. Despite a huge amount of research papers on this topic, a rehabilitation golden standard still has not been established, due to the complexity of this problem. In this review, we point out the basic principles of rehabilitation after arthroscopically assisted ACL reconstruction based on actual practices, as well as the importance of specific procedures for the prevention of complications during the postoperative period. The importance of range-of-motion exercises, early weight bearing, an appropriate gait scheme, patella mobilisation, pain and oedema control, as well as stretching and balance exercises is explained. The functional advantages of closed kinetic chain exercises, as well as their influence on the graft are also described, in comparison to open kinetic chain exercises. The fundamentals of returning to sports are revealed and the specific aspects of rehabilitation regarding graft choice are pointed out. While waiting for new clinical investigations, which are expected to enable the establishment of a rehabilitation golden standard, the outlined principles should be followed. The complexity of this injury requires treatment in highly specialised institutions.

  18. A Review of Some Basic Principles in Fishpond Management

    Directory of Open Access Journals (Sweden)

    J.F.N. Abowei

    2011-11-01

    Full Text Available A review of some basic principles in fishpond management was reviewed to educate fish culturist, private and public sector to effectively manage culture fisheries. Successful pond management requires more than just stocking fish. It is also important to maintain the proper environmental conditions, to monitor fish harvest and growth, check for successful fish reproduction, and to keep out unwanted fish. This is the science of fish management, the solid basis for ensuring good fishing. Good fish management begins with an understanding of your pond’s physical, chemical, and biological features. Pond ecology, fish biology, site selection. Construction, liming, fertilization, brackish water pond management, culture species, stock management, managing fish population, management system, harvesting, fresh water pond management, fish species selection, fish stocking in fresh water ponds, stocking density, feeding, pond testing, diagnosing problems in pond, correcting muddy ponds, fish kills, aquatic weed control, managing other animals, habitat, pond renovation, fish harvesting in fresh water ponds, marketing and legal considerations are other important fish pond management principles the fish culturist need to know.

  19. Physiology of Women's Sexual Function : Basic Knowledge and New Findings

    NARCIS (Netherlands)

    Salonia, Andrea; Giraldi, Annamaria; Chivers, Meredith L.; Georgiadis, Janniko R.; Levin, Roy; Maravilla, Kenneth R.; McCarthy, Margaret M.

    2010-01-01

    Introduction. Data concerning the physiology of female sexual functioning are still obtained from animal studies, but an increasing amount of novel evidence comes from human studies. Aim. To gain knowledge of psychological and biologic physiology of women's sexual functioning, mainly addressing sexu

  20. Introduction to basic immunological methods : Generalities, Principles, Protocols and Variants of basic protocols

    International Nuclear Information System (INIS)

    This manuscript is dedicated to student of biological sciences. It provides the information necessary to perform practical works, the most commonly used in immunology. During my doctoral and post-doctoral periods, panoply of methods was employed in diverse subjects in my research. Technical means used in my investigations were diverse enough that i could extract a set of techniques that cover most the basic immunological methods. Each chapter of this manuscript contains a fairly complete description of immunological methods. In each topic the basic protocol and its variants were preceded by background information provided in paragraphs concerning the principle and generalities. The emphasis is placed on describing situations in which each method and its variants were used. These basic immunological methods are useful for students and even researchers studying the immune system of human, nice and other species. Different subjects showed not only detailed protocols but also photos or/and shemas used as support to illustrate some knowledge or practical knowledge. I hope that students will find this manual interesting, easy to use contains necessary information to acquire skills in immunological practice. (Author)

  1. THE BASIC PRINCIPLES OF RESEARCH IN NEUROEDUCATION STUDIES

    Directory of Open Access Journals (Sweden)

    Ali Nouri

    2016-06-01

    Full Text Available The present paper assembles contributions from the areas of education, psychology, cognitive science, and of course, neuroeducation itself to introduce the basic principles of research in the field of neuroeducation studies. It is particularly important, as such it is a useful way to justify researchers about what neuroeducation as a specific domain do that no other field can do as well or cannot do at all. Based on the literature reviewed, neuroeducational research can be understood as an interdisciplinary endeavor to develop an insightful understanding and holistic picture of problems related to learning and education. It thus epistemologically is based on an integrated methodological pluralism paradigm. This requires researchers to understand multiple methods and methodologies and employ as they formulate their own research projects. Researchers have a critical role to play in providing systematic evidence and conclusions that are scientifically valid and reliable and educationally relevant and usable. One significant implication of this argument is the need to strengthen the quality of the research component in graduate programs of the field and train interested researchers in the identification and formulation of relevant research questions.

  2. Basic Principles of Interpersonal Social Rhythm Therapy in Bipolar Disorder

    Directory of Open Access Journals (Sweden)

    Gokben Hizli Sayar

    2014-08-01

    Full Text Available Interpersonal Social Rhythm Therapy is a psychotherapy modality that helps the patient recognize the relationship between disruptions in social rhythms and the onset of previous episodes of psychiatric disorders. It uses psychoeducation and behavioral techniques to maintain social rhythm and sleep/wake regularity. It is closely related to and ldquo;social zeitgeber theory and rdquo; that emphasizes the importance that social rhythm regularity may play in synchronization of circadian rhythms in individuals with or at risk for bipolar spectrum disorders. Interpersonal and social rhythm therapy have been shown to stabilize social rhythms and enhance course and outcome in bipolar disorder. This review focuses on the theoretical principles and the basic steps of interpersonal and social rhythm therapy as a psychotherapy approach in bipolar disorder. PubMed, Scopus, Google Scholar databases were searched without temporal restriction. Search terms included interpersonal social rhythm therapy, bipolar, mood disorders. Abstracts were reviewed for relevance, and randomized controlled trials of interpersonal and social rhythm therapy in bipolar disorder selected. These researches also summarized on the final part of this review. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2014; 6(4.000: 438-446

  3. The notion and basic principles of restorative justice

    Directory of Open Access Journals (Sweden)

    Ćopić Sanja

    2007-01-01

    Full Text Available One of the most important achievements of the contemporary criminal justice system and criminal policy is development of the concept of restorative justice. Contemporary concept of restorative justice was developed in 1970s on the basis of the criticism of the traditional criminal law and criminal justice system. Since that time, it has been developing through different programs in many countries. Reform of the criminal justice system in Serbia staring from 2002 went into direction of entering elements of restorative justice into existing criminal justice system. In that sense, development of restorative justice is still at the beginning in our country. However, it can be noticed that there is a low level of awareness on the nature and importance of restorative forms of response to crime among our professionals, as well as a lack of understanding of the concept itself. Due to that, the aim of the paper is to enable better understanding of restorative concept in general through defining restorative justice and basic principles it relies on. That may put a basis for further recognition of restorative elements in our criminal justice system, which may provide adequate implementation of relevant provisions of restorative character in practice. .

  4. BASIC PRINCIPLES FOR THE MODERN CLASSIFICATION OF UNMANNED AVIATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    В.П. Харченко

    2012-12-01

    Full Text Available  In view of the basic contemporary classification criteria attempted the classification of unmanned aircraft systems have been attempted  on the basis of available scientific and technical potential, of their applications features,  and prospects for development of information and the aircraft manufacturing technologies. Based on the global trends analysis of unmanned aircraft systems development in determining the prospects for development of unmanned aircraft systems as a class has been discussed the need to use a single general classification system features that reflects the level of functional independence of the aircraft belonging to the UAS and takes into account not only the level of technical excellence, but also the level of development information and logistics systems. The formation principles of unmanned aircraft systems and complexes have been considered due to the UAC development problems, including the issues of the complex architectonics, its full composition, unmanned aircraft controlling methods, and the procedures for the unmanned aviation complex use as a whole taking into account the peculiarities the different UAVs categories application.

  5. BASIC PRINCIPLES OF TRANSPORT TOURISM DEVELOPMENT IN UKRAINE

    Directory of Open Access Journals (Sweden)

    L. V. Martsenyuk

    2013-08-01

    Full Text Available Purpose. Undeveloped infrastructure and the system of public and tourist transport services prevent boom and spread of tourism glory of the country. Therefore, the development of tourist infrastructure and transport communication routes is a priority task. Methodology. Article methodology is based on the use of consequent methodological technique. Findings. Author analyzed the situation of tourism industry in Ukraine, set the basic principles for the tourism development and its priorities. The article contains the author's point of view on the fact that the tourism industry is of paramount importance to the state economics, and the development of this sector of public life should be a priority task for the near future. Originality. According to the author, the development of the inbound tourism is more reasonable, because it provides additional workplaces and exchange earnings. The author insists that the raise of quality level of domestic tourist services to the European standards would accelerate the development of Ukrainian tourism and would attract more holidaymakers from Ukraine and neighbouring countries. Practical value. The rational measures, which were taken regarding the proposed directions for the tourism development, can improve competitiveness of the Ukrainian tourist industry on the European tourist market.

  6. Physiology

    Science.gov (United States)

    Kay, Ian

    2008-01-01

    Underlying recent developments in health care and new treatments for disease are advances in basic medical sciences. This edition of "Webwatch" focuses on sites dealing with basic medical sciences, with particular attention given to physiology. There is a vast amount of information on the web related to physiology. The sites that are included here…

  7. An investigation of the relationship between having recent knowledge in basic biology and student success in Anatomy and Physiology I

    Science.gov (United States)

    Taylor, Edward T.

    Allied Health Programs generally require that students complete coursework in Human Anatomy and Physiology I and II as part of their Pre-Allied Health curriculum. Human Anatomy and Physiology I generally has as a prerequisite some coursework in basic biology. Basic biology as a prerequisite should provide students with the foundation of knowledge in the basic biological principles and processes that will prepare them for the material presented in a Human Anatomy and Physiology I course and the Allied Health Program. The principle question that prompted this study was, Do students need coursework in basic biology to be successful in Anatomy and Physiology I? The purpose of this study was to determine if there was a difference in the exam average obtained in Biology 202, Human Anatomy and Physiology I, for those students who have had, within the previous three years, a foundation course in basic biology as compared to those students who have not, within the previous three years, had a foundation course in basic biology. The current study analyzed data obtained on 642 students who were enrolled in Biology 202, Anatomy and Physiology I, during the Fall semester of 2000 to the Spring semester of 2003 at Wor-Wic Community College. Statistical techniques including an ANOVA, Pearson Product Moment Correlation, and a Multiple Regression Analysis were conducted to reveal any relationships in the data. The dependent variable was the exam average obtained in the independent variables included the time period since the student had taken a basic biology course, sex, age, and college GPA. The results of the ANOVA indicated that there was no relationship between the exam average between current and non-current students, where alpha = 0.05 and p = 0.783. There was statistically significance for GPA, where p = 0 .000. There was also statistically significant interactions between last biology course and GPA, p = 0.05, last biology course, sex, and GPA, p = 0.002. The Pearson Product

  8. The maximum entropy production principle: two basic questions

    OpenAIRE

    Martyushev, Leonid M.

    2010-01-01

    The overwhelming majority of maximum entropy production applications to ecological and environmental systems are based on thermodynamics and statistical physics. Here, we discuss briefly maximum entropy production principle and raises two questions: (i) can this principle be used as the basis for non-equilibrium thermodynamics and statistical mechanics and (ii) is it possible to ‘prove’ the principle? We adduce one more proof which is most concise today.

  9. The Cyclical Relationship Approach in Teaching Basic Accounting Principles.

    Science.gov (United States)

    Golen, Steven

    1981-01-01

    Shows how teachers can provide a more meaningful presentation of various accounting principles by illustrating them through a cyclical relationship approach. Thus, the students see the entire accounting relationship as a result of doing business. (CT)

  10. Basic principles of taxation in the Russian Federation

    OpenAIRE

    PUZYNYA T.A.; BESKROVNAYA V.A.

    2015-01-01

    The tax system of the Russian Federation based on economic and legal principles, to include economic justice, proportionality, efficiency or effectiveness, to legal same the legitimacy of the establishment, the combination of the interests of taxpayers with state authorities. In addition to the principles of taxation often include organizational rules, which imply a common methodological framework in the calculation of taxes and their exhaustive list.

  11. Why are sex and gender important to basic physiology and translational and individualized medicine?

    OpenAIRE

    Miller, Virginia M

    2014-01-01

    Sex refers to biological differences between men and women. Although sex is a fundamental aspect of human physiology that splits the population in two approximately equal halves, this essential biological variable is rarely considered in the design of basic physiological studies, in translating findings from basic science to clinical research, or in developing personalized medical strategies. Contrary to sex, gender refers to social and cultural factors related to being a man or a woman in a ...

  12. Coatings in Dentistry—A Review of Some Basic Principles

    Directory of Open Access Journals (Sweden)

    Karl-Johan M. Söderholm

    2012-07-01

    Full Text Available Different coatings are used in dentistry in an attempt to prevent caries, improve bonding of restorative materials to tooth tissues, and coat implant surfaces in efforts to speed up osseointegration. These are just a few of the many coating applications used in dentistry. The intention of this review is not to cover the entire field of different coatings used in dentistry, because that topic is just too big to be covered in one single paper. Therefore, this review aims to highlight some fundamental coating principles and present these principles to an audience consisting mainly of dentists. To do so, this review will focus on the fundamental principles of coatings, namely surface properties/adhesives in general, since these topics form the foundation for most coating procedures used in dentistry.

  13. Progress in basic principles of limitation in radiation protection

    International Nuclear Information System (INIS)

    For purposes of limitation of harmful factors, e.g. radiation, it is proposed to divide all countless numbers of biological effects into three groups: 1) social important effects (ultimate and effects); 2) intermediate effects (different diseases etc.), which are connected with and controlled by the first group; 3) pure biological effects, importance of which is not known. To determine the first group effects there are identified four indices describing all significant sides of human life: time of life, life-time integral of mental and physical capacity for work, aesthetical satisfaction from organism itself, reproduction of descendants. They reflect the main social and individual interests related to functioning of organism. On the base of weighing these indices it is suggested the united general index of health in form of time of a full life. The united index can be used for different principles of limitation (based on threshold, acceptable risk, maximum benefit). To realize the principle of maximum public benefit as ideal principle in the future limitation all benefit and detriment from utilization of harmful sources must be expressed in the united index of health (instead of money), which is the greatest value of individual and society. Authors suggest to standartize ionizing radiation on the general methodological approaches that were acceptable to non-ionizing factors too

  14. The "Core Principles" of Physiology: What Should Students Understand?

    Science.gov (United States)

    Michael, Joel; Modell, Harold; McFarland, Jenny; Cliff, William

    2009-01-01

    The explosion of knowledge in all of the biological sciences, and specifically in physiology, has created a growing problem for educators. There is more to know than students can possibly learn. Thus, difficult choices have to be made about what we expect students to master. One approach to making the needed decisions is to consider those "core…

  15. Nonverbal Communication : Basic Principles and Practical Applications in Health Care

    OpenAIRE

    PATTERSON, Miles L.; 飯塚, 雄一; Miles L., PATTERSON; Yuichi, IIZUKA

    2006-01-01

    Nonverbal communication is a pervasive influence in every life. Furthermore, in most setting, nonverbal communication has a greater impact on interactions than does verbal communication. In this article, we first describe the basic processes involved in nonverbal communication and then briefly examine the factors affecting patterns of nonverbal communication - biology, culture, gender, and personality. Finally, we discuss the role of nonverbal communication in health care settings. Nonverbal ...

  16. BASIC PRINCIPLES FOR THE MODERN CLASSIFICATION OF UNMANNED AVIATION SYSTEMS

    OpenAIRE

    Харченко, В.П.; Національний авіаційний університет; Прусов, Д.Е.; Національний авіаційний університет

    2012-01-01

     In view of the basic contemporary classification criteria attempted the classification of unmanned aircraft systems have been attempted  on the basis of available scientific and technical potential, of their applications features,  and prospects for development of information and the aircraft manufacturing technologies. Based on the global trends analysis of unmanned aircraft systems development in determining the prospects for development of unmanned aircraft systems as a class has been dis...

  17. Welding As Science: Applying Basic Engineering Principles to the Discipline

    Science.gov (United States)

    Nunes, A. C., Jr.

    2010-01-01

    This Technical Memorandum provides sample problems illustrating ways in which basic engineering science has been applied to the discipline of welding. Perhaps inferences may be drawn regarding optimal approaches to particular welding problems, as well as for the optimal education for welding engineers. Perhaps also some readers may be attracted to the science(s) of welding and may make worthwhile contributions to the discipline.

  18. Education and Development: A return to basic principles

    OpenAIRE

    Heyneman, Stephen P

    2010-01-01

    As a political strategy, Education-for-All has been a failure. Originally designed to attract education investments over other priorities, the portion of donor resources devoted to education has been stagnant. The strategy has made a fetish out of primary education at the expense of education sector development; generated a donor monopoly over client interests and exaggerated the role of the state in education provision. Stephen P. Heyneman explains why it is crucial now to return to basic pr...

  19. Ultra-high energy physics and standard basic principles

    OpenAIRE

    Gonzalez-Mestres Luis

    2014-01-01

    It has not yet been elucidated whether the observed flux suppression for ultra-high energy cosmic rays (UHECR) at energies above ≃ 4 x 1019 eV is a signature of the Greisen-Zatsepin-Kuzmin (GZK) cutoff or a consequence of other phenomena. In both cases, violations of the standard fundamental principles of Physics can be present and play a significant role. They can in particular modify cosmic-ray interactions, propagation or acceleration at very high energy. Thus, in a long-term program, UHEC...

  20. Radiofrequency Ablation of Thyroid Nodules: Basic Principles and Clinical Application

    Directory of Open Access Journals (Sweden)

    Ji Hoon Shin

    2012-01-01

    Full Text Available Radiofrequency (RF ablation has been gaining popularity as a minimally invasive treatment for benign thyroid nodules regardless of the extent of the solid component. RF ablation of benign nodules demonstrated volume reductions of 33–58% after one month and 51–85% after six months, while solving nodule-related clinical problems. RF ablation has recently shown positive short-term results for locoregional control as well as symptom improvement in patients with recurrent thyroid cancers. This paper reviews the basic physics, indications, patient preparation, devices, procedures, clinical results, and complications of RF ablation.

  1. [Basic principles of 18F-fluorodeoxyglucose positron emission tomography].

    Science.gov (United States)

    Standke, R

    2002-01-01

    Positron emission tomography uses photons to receive regional information about dynamic, physiologic, and biochemical processes in the living body. A positron decay is measured indirectly by the simultaneous registration of both gamma rays created by the annihilation. The event is counted, if two directly opposite located detectors register gamma rays in coincidence. Unfortunately the detectors of a positron emission tomography system do not register only true coincident events. There are also scattered and random coincidences. Different types of positron tomographs are presented and scintillation crystals, which are in use for positron emission tomography are discussed. The 2D- and 3D-acquisition methods are described as well as preprocessing methods, such as correction for attenuation, scatter and dead time. For quantification the relative parameter standard uptake value (SUV) is explained. Finally hybrid systems, such as combined positron emission tomography/computed tomography scanners and the use of computed tomography data for attenuation correction are introduced. PMID:12506765

  2. Differences between application of some basic principles of quantum mechanics on atomic and mesoscopic levels

    OpenAIRE

    Nikulov, Alexey

    2005-01-01

    Formalism of the quantum mechanics developed for microscopic (atomic) level comes into collision with some logical difficulties on mesoscopic level. Some fundamental differences between application of its basic principles on microscopic and mesoscopic levels are accentuated.

  3. [From basic principles to clinical applications on transcutaneous vaccine].

    Science.gov (United States)

    Okada, Naoki

    2013-01-01

    The recent vigorous transnational migration of people and materials reflecting the development of transportation facilities, changes in social structure, and war disasters has increased the global spread of emerging and re-emerging infectious diseases. Vaccine, which is the major fundamental prophylaxis against infectious diseases, has greatly contributed to the maintenance and improvement of human health worldwide. However, the disadvantages of conventional injection systems hamper the speedy mass-vaccination and the global distribution of vaccines. Transcutaneous immunization systems, which are easy-to-use and low-invasive methods of vaccination, have the potential to overcome certain issues associated with injectable vaccinations. In this review, we provide an outline of recent trends in the development of techniques for the transcutaneous delivery of vaccine antigens. We also introduce basic and clinical research involving our transcutaneous immunization systems that incorporate self-dissolving microneedle patch. PMID:24292185

  4. Electrons in molecules from basic principles to molecular electronics

    CERN Document Server

    Launay, Jean-Pierre

    2014-01-01

    The purpose of this book is to provide the reader with essential keys to a unified understanding of the rapidly expanding field of molecular materials and devices: electronic structures and bonding, magnetic, electrical and photo-physical properties, and the mastering of electrons in molecular electronics. Chemists will discover how basic quantum concepts allow us to understand the relations between structures, electronic structures, and properties of molecular entities and assemblies, and to design new molecules and materials. Physicists and engineers will realize how the molecular world fits in with their need for systems flexible enough to check theories or provide original solutions to exciting new scientific and technological challenges. The non-specialist will find out how molecules behave in electronics at the most minute, sub-nanosize level. The comprehensive overview provided in this book is unique and will benefit undergraduate and graduate students in chemistry, materials science, and engineering, ...

  5. Optical properties of metallic nanoparticles basic principles and simulation

    CERN Document Server

    Trügler, Andreas

    2016-01-01

    This book introduces the fascinating world of plasmonics and physics at the nanoscale, with a focus on simulations and the theoretical aspects of optics and nanotechnology. A research field with numerous applications, plasmonics bridges the gap between the micrometer length scale of light and the secrets of the nanoworld. This is achieved by binding light to charge density oscillations of metallic nanostructures, so-called surface plasmons, which allow electromagnetic radiation to be focussed down to spots as small as a few nanometers. The book is a snapshot of recent and ongoing research and at the same time outlines our present understanding of the optical properties of metallic nanoparticles, ranging from the tunability of plasmonic resonances to the ultrafast dynamics of light-matter interaction. Beginning with a gentle introduction that highlights the basics of plasmonic interactions and plasmon imaging, the author then presents a suitable theoretical framework for the description of metallic nanostructu...

  6. Embarrassment as a key to understanding cultural differences. Basic principles of cultural analysis

    DEFF Research Database (Denmark)

    Bouchet, Dominique

    1995-01-01

    I introduce here the principles I use in my investigation of intercultural marketing and management. I explain how I discovered them, and show how they spring from a theoretical understanding of the dynamic of cultural differences. One of the basic methodological principles for my analysis of...

  7. Basic versus applied research: Julius Sachs (1832–1897) and the experimental physiology of plants

    OpenAIRE

    Kutschera, Ulrich

    2015-01-01

    The German biologist Julius Sachs was the first to introduce controlled, accurate, quantitative experimentation into the botanical sciences, and is regarded as the founder of modern plant physiology. His seminal monograph Experimental-Physiologie der Pflanzen (Experimental Physiology of Plants) was published 150 y ago (1865), when Sachs was employed as a lecturer at the Agricultural Academy in Poppelsdorf/Bonn (now part of the University). This book marks the beginning of a new era of basic a...

  8. Transformational Teaching: Theoretical Underpinnings, Basic Principles, and Core Methods

    Science.gov (United States)

    Slavich, George M.; Zimbardo, Philip G.

    2012-01-01

    Approaches to classroom instruction have evolved considerably over the past 50 years. This progress has been spurred by the development of several learning principles and methods of instruction, including active learning, student-centered learning, collaborative learning, experiential learning, and problem-based learning. In the present paper, we suggest that these seemingly different strategies share important underlying characteristics and can be viewed as complimentary components of a broader approach to classroom instruction called transformational teaching. Transformational teaching involves creating dynamic relationships between teachers, students, and a shared body of knowledge to promote student learning and personal growth. From this perspective, instructors are intellectual coaches who create teams of students who collaborate with each other and with their teacher to master bodies of information. Teachers assume the traditional role of facilitating students’ acquisition of key course concepts, but do so while enhancing students’ personal development and attitudes toward learning. They accomplish these goals by establishing a shared vision for a course, providing modeling and mastery experiences, challenging and encouraging students, personalizing attention and feedback, creating experiential lessons that transcend the boundaries of the classroom, and promoting ample opportunities for preflection and reflection. We propose that these methods are synergistically related and, when used together, maximize students’ potential for intellectual and personal growth. PMID:23162369

  9. Basic principles of taxation of small-scale enterprises in the Russian Federation

    OpenAIRE

    Khodyreva Viktoriia Andreevna

    2015-01-01

    This research is devoted to general principles of taxation of small-scale enterprises. Development of small-scale enterprises is one of the most important lines of tax policy in Russian Federation. The development of principles of taxation is important while forming a strong state system of taxation. In this work basic principles and some specific are provided. This work is of great scientific interest to law students, graduates, teachers and other persons interested in law and particularly i...

  10. Challenges, basic principles and methodologies for decadal predictability and forecasts

    International Nuclear Information System (INIS)

    Within the framework of the 5. coupled model inter-comparison project, an ensemble of coordinated decadal forecast simulations have been carried out, for the first time, by the climate community. This new initiative first aims at better understanding the decadal modulations that are superimposed on the anthropogenic-forced warming tendency and that are mostly explained, at such a timescale, by the internal variability in the ocean. The goal of this initiative is then to provide a first assessment of the climate predictability at decadal timescale. Forecasts differ from climate projections by the mandatory step of initialization of the model components either to direct observations or their reconstruction via the reanalyzes. They aim at simulating at best the observed fluctuations whereas projections and historical simulations only estimate the climate response to so-called external forcings such as solar activity, volcanism and anthropogenic perturbations. The goal of this article is primarily to review the basics of the decadal forecasts (concepts, methodologies, difficulties and limits) and to present preliminary and simple results on predictive skill estimated from hind-casts over 1960-2010. (authors)

  11. Basic principles of pharmaceutical science in Ayurvĕda.

    Science.gov (United States)

    Subhose, Varanasi; Srinivas, Pitta; Narayana, Ala

    2005-01-01

    Pharmaceutical is one of the allied branches of science, which is closely associated with Medical science. Today pharmaceutical chemistry and pharmacognosy are playing important role in treatment for a disease and its prevention. Herbal medicines are being used by about 80% of the world population mostly in the developing countries in the primary health care. There has been an upsurge in demand for the Phyto-pharmaceutical products of Ayurvĕda in western nations, because of the fact that the synthetic drugs are considered to be unsafe. Due to this many national and multinational pharmaceutical companies are now concentrating on manufacturing of Ayurvĕdic Phyto-pharmaceutical products. Ayurvĕda is the Indian traditional system of medicine, which also deals about pharmaceutical science. The Ayurvĕdic knowledge of the pharmaceutical science is scattered in Ayurvĕdic classical texts. Săranghadhara Samhita, which is written by Săranghadhara, explain systematically about the information of the Ayurvĕdic pharmaceutical science and also updated it. Industrialized manufacturing of Ayurvĕdic dosage forms has brought in new challenges like deviation from basic concepts of medicine preparation. Săranghadhara Samrhită the devout text on pharmaceutics in Ayurvĕda comes handy to solve such problems, as the methods described are very lucid and easy to follow. PMID:17333665

  12. Neutron spin manipulation optics: basic principles and possible applications

    International Nuclear Information System (INIS)

    A number of basic elements for neutron spin manipulation optics (NSMO) based on Larmor and non-Larmor (quantum) precessions under reflection are considered. It is concluded that transition to 3D in neutron polarization optics may bring additional instrumental possibilities. New neutron optical devices will include spin turners (particularly, π/2-turners and π- turners, or flippers), spin precessors and antiprecessors, 3D-polarizers, 3D-analyzers, 3D- rotators, spin manipulators, hyper-polarizers. The innovative neutron optics is directly applicable to developing 3D polarization and polarimetry techniques, such as reflectometry with 3D- polarimetry, Neutron optical Spin Echo (NoSE), including compact NoSE and TOF NoSE schemes. A hyper-polarizer is a device which not only separates neutrons with the opposite spins, but also flips the 'wrong' spins. Thus, hyper-polarizers can double the intensity of polarized neutron beams, although a gain in the intensity can be achieved only with the increase either in the angular divergence or in the width of the beam, in full accordance with the Liouville theorem. The tasks to be solved for implementation of the NSMO concepts are discussed.

  13. Nondestructive Testing Eddy Current Basic Principles RQA/M1-5330.12 (V-I).

    Science.gov (United States)

    National Aeronautics and Space Administration, Huntsville, AL. George C. Marshall Space Flight Center.

    As one in the series of programmed instruction handbooks, prepared by the U.S. space program, home study material is presented in this volume concerning familiarization and orientation on basic eddy current principles. The subject is presented under the following headings: Basic Eddy Current Concepts, Eddy Current Generation and Distribution,…

  14. New Simulation Methods to Facilitate Achieving a Mechanistic Understanding of Basic Pharmacology Principles in the Classroom

    Science.gov (United States)

    Grover, Anita; Lam, Tai Ning; Hunt, C. Anthony

    2008-01-01

    We present a simulation tool to aid the study of basic pharmacology principles. By taking advantage of the properties of agent-based modeling, the tool facilitates taking a mechanistic approach to learning basic concepts, in contrast to the traditional empirical methods. Pharmacodynamics is a particular aspect of pharmacology that can benefit from…

  15. Ultra-high energy physics and standard basic principles

    Directory of Open Access Journals (Sweden)

    Gonzalez-Mestres Luis

    2014-04-01

    Full Text Available It has not yet been elucidated whether the observed flux suppression for ultra-high energy cosmic rays (UHECR at energies above ≃ 4 x 1019 eV is a signature of the Greisen-Zatsepin-Kuzmin (GZK cutoff or a consequence of other phenomena. In both cases, violations of the standard fundamental principles of Physics can be present and play a significant role. They can in particular modify cosmic-ray interactions, propagation or acceleration at very high energy. Thus, in a long-term program, UHECR data can hopefully be used to test relativity, quantum mechanics, energy and momentum conservation, vacuum properties... as well as the elementariness of standard particles. Data on cosmic rays at energies ≃ 1020 eV may also be sensitive to new physics generated well beyond Planck scale. A typical example is provided by the search for possible signatures of a Lorentz symmetry violation (LSV associated to a privileged local reference frame (the "vacuum rest frame", VRF. If a VRF exists, the internal structure of standard particles at ultra-high energy can undergo substantial modifications. Similarly, the conventional particle symmetries may cease to be valid at such energies instead of heading to a grand unification and the structure of vacuum may no longer be governed by standard quantum field theory. Then, the question whether the notion of Planck scale still makes sense clearly becomes relevant and the very grounds of Cosmology can undergo essential modifications. UHECR studies naturally interact with the interpretation of WMAP and Planck observations. Recent Planck data analyses tend to confirm the possible existence of a privileged space direction. If the observed phenomenon turns out to be a signature of the spinorial space-time (SST we suggested in 1996-97, then conventional Particle Physics may correspond to the local properties of standard matter at low enough energy and large enough distances. This would clearly strengthen the cosmological

  16. On the Basic Principle of Civil Law%民法基本原则研究

    Institute of Scientific and Technical Information of China (English)

    陈建国

    2013-01-01

    The basic principle of the civil law embodies the basic concepts of civil law ,which is highly abstract and generalization of the civil law system and has important significance to guide the civil law and helps carry out the civil justice and civil activities smoothly .To study the basic principle of civil law ,first of all ,we should grasp the meaning and characteristics of the basic principles of the civil law to conduct in-depth analysis .Secondly ,we should study the development of the basic principles of the civil law of the world and make a comprehensive analysis of the basic content of the basic principles of civil law . Finally ,by studying the function and role of the basic principles of the civil law ,we can overcome the limits of statute law .We hope that through the in -depth study and analysis of the basic principles of the civil law , we can deepen our understanding of the basic principles of the civil law ,fully exert the function and basic principles of the civil law and serve the socialist civilization of rule by promoting law construction and economic and social development .%  民法基本原则体现着民法的基本理念,是对民事法律制度的高度抽象和概括,对指导民事法律立法、民事司法以及民事活动的顺利进行都具有重要的意义。要研究民法的基本原则,首先,要对民法基本原则的含义和特征进行深入的分析。其次,了解世界范围内民法基本原则的发展历程,全面分析我国民法基本原则的基本内容。最后,通过发挥民法基本原则的功能和作用,来克服我国成文法的局限性。希望能够通过对民法基本原则的深入研究和剖析,加深我们对民法基本原则的认识和理解,充分发挥民法基本原则的功能和作用,为社会主义法治文明建设和经济社会发展服务。

  17. Using the principles of circadian physiology enhances shift schedule design

    International Nuclear Information System (INIS)

    Nuclear power plants must operate 24 h, 7 days a week. For the most part, shift schedules currently in use at nuclear power plants have been designed to meet operational needs without considering the biological clocks of the human operators. The development of schedules that also take circadian principles into account is a positive step that can be taken to improve plant safety by optimizing operator alertness. These schedules reduce the probability of human errors especially during backshifts. In addition, training programs that teach round-the-clock workers how to deal with the problems of shiftwork can help to optimize performance and alertness. These programs teach shiftworkers the underlying causes of the sleep problems associated with shiftwork and also provide coping strategies for improving sleep and dealing with the transition between shifts. When these training programs are coupled with an improved schedule, the problems associated with working round-the-clock can be significantly reduced

  18. Using the principles of circadian physiology enhances shift schedule design

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, J.J.; Moore-Ede, M.C.

    1987-01-01

    Nuclear power plants must operate 24 h, 7 days a week. For the most part, shift schedules currently in use at nuclear power plants have been designed to meet operational needs without considering the biological clocks of the human operators. The development of schedules that also take circadian principles into account is a positive step that can be taken to improve plant safety by optimizing operator alertness. These schedules reduce the probability of human errors especially during backshifts. In addition, training programs that teach round-the-clock workers how to deal with the problems of shiftwork can help to optimize performance and alertness. These programs teach shiftworkers the underlying causes of the sleep problems associated with shiftwork and also provide coping strategies for improving sleep and dealing with the transition between shifts. When these training programs are coupled with an improved schedule, the problems associated with working round-the-clock can be significantly reduced.

  19. Some basic principles in dynamic theory of viscoelastic materials with voids

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    According to the basic idea of classical yin-yang complementarity and modern dual-complementarity, in a simple and unified way proposed by Luo, some basic principles in the dynamic theory of viscoelastic materials with voids can be estab- lished systematically. In this paper, an important integral relation in terms of con- volutions is given, which can be considered as the generalized principle of virtual work in mechanics. Based on this relation, it is possible not only to obtain the principle of virtual work and the reciprocal theorem, but also to derive systemati- cally the complementary functionals for the eight-field, six-field, four-field simpli- fied Gurtin-type variational principles and the potential energy-functional for the two-field one in the dynamic theory of viscoelastic materials with voids by the generalized Legendre transformations given in this paper. Furthermore, with this approach, the intrinsic relationship among various principles can be explained clearly.

  20. Some basic principles in dynamic theory of viscoelastic materials with voids

    Institute of Scientific and Technical Information of China (English)

    LUO En; LI WeiHua

    2007-01-01

    According to the basic idea of classical yin-yang complementarity and modern dual-complementarity, in a simple and unified way proposed by Luo, some basic principles in the dynamic theory of viscoelastic materials with voids can be established systematically. In this paper, an important integral relation in terms of convolutions is given, which can be considered as the generalized principle of virtual work in mechanics. Based on this relation, it Is possible not only to obtain the principle of virtual work and the reciprocal theorem, but also to derive systematically the complementary functionals for the eight-field, six-field, four-field simplified Gurtin-type variational principles and the potential energy-functional for the two-field one in the dynamic theory of viscoelastic materials with voids by the generalized Legendre transformations given in this paper. Furthermore, with this approach, the intrinsic relationship among various principles can be explained clearly.

  1. Some basic principles for the linear theory of piezoelectric micropolar elastodynamics

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    According to the basic idea of classical yin-yang complementarity and modern dual-complementarity,in a simple and unified way proposed by Luo,some basic principles in the linear theory of piezoelectric micropolar elastodynamics can be established systematically. In this paper,an important integral relation in terms of convolutions is given,which can be considered as the generalized principle of virtual work in mechanics. Based on this relation,it is not only possible to obtain the principle of virtual work and the reciprocal theorem,but also to systematically derive the complementary functionals for the eleven-field,nine-field and six-field simplified Gurtin-type variational principles and the potential energy-functional for the three-field one in the linear theory of piezoelectric micropolar elastodynamics by the generalized Legendre transformations given in this paper. Furthermore,with this approach,the intrinsic relationships among various principles can be explained clearly.

  2. Feeling force: physical and physiological principles enabling sensory mechanotransduction.

    Science.gov (United States)

    Katta, Samata; Krieg, Michael; Goodman, Miriam B

    2015-01-01

    Organisms as diverse as microbes, roundworms, insects, and mammals detect and respond to applied force. In animals, this ability depends on ionotropic force receptors, known as mechanoelectrical transduction (MeT) channels, that are expressed by specialized mechanoreceptor cells embedded in diverse tissues and distributed throughout the body. These cells mediate hearing, touch, and proprioception and play a crucial role in regulating organ function. Here, we attempt to integrate knowledge about the architecture of mechanoreceptor cells and their sensory organs with principles of cell mechanics, and we consider how engulfing tissues contribute to mechanical filtering. We address progress in the quest to identify the proteins that form MeT channels and to understand how these channels are gated. For clarity and convenience, we focus on sensory mechanobiology in nematodes, fruit flies, and mice. These themes are emphasized: asymmetric responses to applied forces, which may reflect anisotropy of the structure and mechanics of sensory mechanoreceptor cells, and proteins that function as MeT channels, which appear to have emerged many times through evolution. PMID:26566115

  3. Basic requirements and principles of creation onboard diagnostic systems of locomotives

    OpenAIRE

    Bodnar, YE. B.

    2014-01-01

    Purpose. Justification of the basic principles of construction on-board diagnostic systems locomotive and choose from high-performance and reliable interface for the exchange of information on-board diagnostic systems. Methodology. Problem of getting correct and adequate information about the technical state of the technical object is solved with the use and compliance of the fundamental principles of modern computers. Findings. High-performance and reliable interface to exchange messages bet...

  4. Nahj al-Balagha in The Axis of Basic Principles of Islamic Law of War

    OpenAIRE

    NARGÜL, Veysel

    2013-01-01

    In this study, the information about war in Nahj al-Balagha, which contains many views of Hz Ali on many subjects, is considered in the light of basic principles of Islamic law of war. After the brief information of the understanding the war in Islam, the information in the Nahj al-Balagha about war is expressed in the light of basic principles of Islamic law of war, beneath three headlines as before war, during and after war. In the final analysis, it is emphasized that whether the informati...

  5. BASIC PRINCIPLES AND SEQUENCE OF MANAGEMENT DECISION-MAKING IN SUBSTANTIATING THE ENTERPRISES'' REAL INVESTMENTS EXPEDIENCY

    OpenAIRE

    Kukhta, P.

    2012-01-01

    There were revealed the basic principles of evaluating the real investments effectiveness, compliance with which will ensure the economic feasibility of projects, simplification of the evaluation process and rational behaviour of economic entities in their implementation. Sequence of forming the components of the systematic approach to the approval of management decisions was defined.

  6. [The theoretical analysis of Fick's equation. On the centennial of the use of Fick's principle in physiology].

    Science.gov (United States)

    Karpman, V L

    1975-09-01

    In the first section Adolf Fick's outstanding scientific performances are pointed out in their historical sequence, particularly the derivation of the laws of diffusion (1855) and the basic equation for determining the heart-minute-volume (Fm) by O2-absorption per time (V02) and arteriovenous O2-difference (AVD), known as Fick's Principle. The latter was derived theoretically in 1870 by Fick, but it found it practical employment by other investigators, in dog not before 1886 and in man not earlier than 1930. In the following two sections the universality of Fick's Principle is shown by explaining its internal relation 1. to Fick's first law of diffusion and 2. to the general law of solution. This is done by mathematical transformation of the relations (formulas)of the physical resp. the physiological standards (parameters). By analyzing the diffusion of a substance into a streaming fluid according to the first diffusion law, perfectly isomorphic equations to Fick's Principle (No. 7 and No. 9) are obtained by what Fick's formula as a determinant of the heart-minute-volume is just proved to be derivable from Fick's first diffusion law. Furthermore by transforming the trivial formula for the determination of substance concentration in a fluid provement is given, that Fick's Principle may be considered a variant of the solution theory. By this the internal relation of the so-called dilution respectively indicating methods depending on the Stewart-Hamilton-Principle to the original Fick's Principle is made visible. In the last section an attempt is made to produce a relation to 1. the so-called physical methods determining the minute volume which primarily are known as a measurement for stroke volume and frequency, and, besides that, 2. to Vierordt's equation, by which the heart-minute-volume is determinable from circulating blood volume and circulation time. This trial is made by equating the value of the minute volume given by Fick's Principle (VO2/AVD) with the

  7. Human-on-a-chip design strategies and principles for physiologically based pharmocokinetics/pharmacodynamics modeling

    OpenAIRE

    Abaci, Hasan Erbil; Shuler, Michael L.

    2015-01-01

    Advances in maintaining multiple human tissues on microfluidic platforms has led to a growing interest in developing microphysiological systems for drug development studies. Determining the proper design principles and scaling rules for body-on-a-chip systems is critical for their strategic incorporation into physiologically based pharmacokinetic (PBPK)/pharmacodynamic model (PD) -aided drug development. While the need for a functional design considering organ-organ interactions has been cons...

  8. [Basic principles of comprehensive approach to the development of aerosol inhalation equipment].

    Science.gov (United States)

    Liutov, G P

    1994-01-01

    The comprehensive approach to choosing the nomenclature of aerosol inhalers is based on the definition of the basic principles in the development of apparatuses as to the optimization of their consumer qualities, the unification of basic blocks and the enhancement of their reliability. With the use of the approach, two models of fixed inhalers have been put into practice, a portable universal inhaler is brought to a commercial level, and two models of portable heat humid inhalers are under development, which is in full conformity with health care requirements for this medical equipment. PMID:7707891

  9. Reference values for basic human anatomical and physiological characteristics for use in radiation protection

    International Nuclear Information System (INIS)

    A new publication prepared by the ICRP Task Group on Reference Man. Basic anatomical and physiological data for use in radiological protection: reference values, is focused on those human characteristics that are important for dosimetric calculations. Moving from the past emphasis on a Reference Man. the new report presents a series of reference values for both male and female subjects of six different ages - newborn, 1, 5, 10, 15 y, and adult. In selecting reference values, the task group has used data on Western Europeans and North Americans because these populations have been well studied with respect to anatomy, body composition and physiology. When appropriate, comparisons are made between the chosen reference values and data from several Asian populations. The reference values for height and body mass are higher than those reported for various Asian populations. However, the reported masses of individual organs and tissues, particularly for China and Japan, are similar to the reference values. (author)

  10. Examining the Ethical Dilemmas in Terminating the Pregnancy Through the Basic Ethical Principles

    Directory of Open Access Journals (Sweden)

    Engin Kurt

    2016-06-01

    Full Text Available Termination of pregnancy is an event that takes place at the request of expectant parents or due to reasons beyond their desire. However, in the presence of appropriate indications, there is no need for abortion debate. In this case, it is important to terminate the pregnancy with the request of expectant parents. Even if cessation of the pregnancy is performed within a legal framework, basic ethical principles, such as autonomy, do no harm, being useful and fairness should be applied. Precisely the problem for physicians already emerges at this point and the physicians can fall in a dilemma about how to behave with the mother or the fetus. In this article, ethical dilemmas that may arise in termination of pregnancy will be discussed briefly in accordance with the basic ethical principles.

  11. Exploration in Classroom Teaching of “Introduction to the Basic Principles of Marxism” in Universities

    Directory of Open Access Journals (Sweden)

    Li Zeng

    2011-11-01

    Full Text Available In order to have a systematic theoretical education of Marxism among university students, help university students master the world outlook and methodology of Marxism, set up Marxism’s outlook on life and sense of worth, learn to use the world outlook and methodology of Marxism to observe and analyze problems and cultivate and improve university students’ capacity in applying Marxism theory to analyze and resolve actual problems, teachers have to have positive exploration in the classroom teaching in teaching of “Introduction to the Basic Principles of Marxism” in colleges and universities, based on human-orientation, establish teachers’ leading role and students’ subject position, change the traditional concepts, realize three changes in the process of teaching, keep pace with the times, continuously update means of teaching, connect theory with reality, reflect the methodology significance of courses and enhance effectiveness of the classroom teaching of “Introduction to the Basic Principles of Marxism”.

  12. Basic Principles of Industrial Electric Power Network Computer Aided Design and Engineering

    Directory of Open Access Journals (Sweden)

    M. Fursanov

    2012-01-01

    Full Text Available A conceptual model for a computer aided design and engineering system has been developed in the paper. The paper presents basic automation process principles including a graphical representation   network and calculation results, convenient user interface, automatic mode calculation, selection of transformer rated power and cross-section area of wires. The developed algorithm and program make it possible to save time and improve quality of project implementation.

  13. Basic Principles and Utilization Possibilities’ of Ultrasonic Phased Array in Material Nondestructive Evaluation

    OpenAIRE

    Ivo Cap; Klara Capova; Dagmar Faktorova

    2004-01-01

    The paper deals with the basic principles of operation and with the utilization possibilities of phased array (PA) in materials nondestructive testing (NDT). The first part deals with description of PA arrangement modes, which enable to generate, focus and steer the ultrasonic beem. The second part deals with the description of electromagnetic acoustic transducer PA operation. The last part deals with the description of the utilization of PA in nondestructive testing of conductive materials a...

  14. BASIC PRINCIPLES AND CONCEPTS UNDERLYING RECENT ADVANCES IN MRI OF THE DEVELOPING BRAIN

    OpenAIRE

    Panigrahy, Ashok; Borzage, Matthew; Blüml, Stefan

    2010-01-01

    Over the last decade, magnetic resonance imaging has become an essential tool in the evaluation of both in vivo human brain development and perinatal brain injury. Recent technology including MR compatible neonatal incubators, neonatal head coils, advanced MR pulse sequences and 3T field strength magnets allow high quality MR imaging studies to be performed on sick neonates. This article will review basic principles and concepts underlying recent advances in MR spectroscopy, diffusion, perfus...

  15. An assessment of adherence to basic ecological principles by payments for ecosystem service projects.

    Science.gov (United States)

    Prager, C M; Varga, A; Olmsted, P; Ingram, J C; Cattau, M; Freund, C; Wynn-Grant, R; Naeem, S

    2016-08-01

    Programs and projects employing payments for ecosystem service (PES) interventions achieve their objectives by linking buyers and sellers of ecosystem services. Although PES projects are popular conservation and development interventions, little is known about their adherence to basic ecological principles. We conducted a quantitative assessment of the degree to which a global set of PES projects adhered to four ecological principles that are basic scientific considerations for any project focused on ecosystem management: collection of baseline data, identification of threats to an ecosystem service, monitoring, and attention to ecosystem dynamics or the formation of an adaptive management plan. We evaluated 118 PES projects in three markets-biodiversity, carbon, and water-compiled using websites of major conservation organizations; ecology, economic, and climate-change databases; and three scholarly databases (ISI Web of Knowledge, Web of Science, and Google Scholar). To assess adherence to ecological principles, we constructed two scientific indices (one additive [ASI] and one multiplicative [MSI]) based on our four ecological criteria and analyzed index scores by relevant project characteristics (e.g., sector, buyer, seller). Carbon-sector projects had higher ASI values (P water-sector projects and marginally higher ASI scores (P budget. These findings suggest, at this critical phase in the rapid growth of PES projects, that fundamental ecological principles should be considered more carefully in PES project design and implementation in an effort to ensure PES project viability and sustainability. PMID:26502915

  16. BASIC REQUIREMENTS AND PRINCIPLES OF CREATION ONBOARD DIAGNOSTIC SYSTEMS OF LOCOMOTIVES

    Directory of Open Access Journals (Sweden)

    YE. B. Bodnar

    2014-01-01

    Full Text Available Purpose. Justification of the basic principles of construction on-board diagnostic systems locomotive and choose from high-performance and reliable interface for the exchange of information on-board diagnostic systems. Methodology. Problem of getting correct and adequate information about the technical state of the technical object is solved with the use and compliance of the fundamental principles of modern computers. Findings. High-performance and reliable interface to exchange messages between different units of management systems and on-board diagnostic systems was selected. Properties which are required high data rate, high reliability and low error rate of information transfer. Originality. The main principles of building on-board diagnostic systems which ensure compliance locomotives accumulation of accurate and adequate information about the technical condition which is necessary to organize its maintenance and repair were formulated. Practical value. Diagnostic equipment designed with use of requirements set forth above and principles will affect the technical condition of the engine, increasing the likelihood of uptime, productivity and locomotive repair teams. The introduction of on-board diagnostic systems and stationary locomotives will significantly improve the system and optimize their maintenance costs of maintenance and repairs. Besides, information about diagnostic parameters changing accumulated with the aim of airborne systems will be used in order to create mathematical models that, in turn, will organize a system of maintenance and predict the technical condition of locomotives

  17. Zebrafish housing systems: a review of basic operating principles and considerations for design and functionality.

    Science.gov (United States)

    Lawrence, Christian; Mason, Timothy

    2012-01-01

    The strategies for housing zebrafish used in biomedical research have evolved considerably over the past three decades. To keep pace with the rapid expansion and development of the zebrafish model system, the field has generally moved from keeping fish at the level of aquarium hobbyist to that of industrialized, recirculating aquaculture. Numerous commercial system vendors now offer increasingly sophisticated housing systems based on design principles that maximize the number of animals that can be housed in a given space footprint, and they are thus able to support large and diverse research programs. This review is designed to provide managers, lab animal veterinarians, investigators, and other parties responsible for care and use of these animals with a comprehensive overview of the basic operating and design principles of zebrafish housing systems. This information can be used to help plan the construction of new facilities and/or the upgrade and maintenance of existing operations. PMID:23382349

  18. RENEWAL OF BASIC LAWS AND PRINCIPLES FOR POLAR CONTINUUM THEORIES (Ⅴ)-POLAR THERMOMECHANICAL CONTINUA

    Institute of Scientific and Technical Information of China (English)

    戴天民

    2003-01-01

    The purpose is to reestablish rather complete basic balance equations and boundary conditions for polar thermomechanical continua based on the restudy of the traditional theories of micropolar thermoelasticity and thermopiezoelectricity. The equations of motion and the local balance equation of energy rate for micropolar thermoelasticity are derived from the rather complete principle of virtual power. The equations of motion, the balance equation of entropy and all boundary conditions are derived from the rather complete Hamilton principle. The new balance equations of momentum and energy rate which are essentially different from the existing results are presented. The corresponding results of micromorphic thermoelasticity and couple stress elastodynamics may be naturally obtained by the transition and the reduction from the micropolar case, respectively. Finally, the results of micropolar thermopiezoelectricity are directly given.

  19. The Achromatic Telescopic Squeezing Scheme: Basic Principles and First Demonstration at the LHC

    CERN Document Server

    Fartoukh, S; Hofle, W; Lamont, M; de Maria, R; Miyamoto, R; Muller, G; Ponce, L; Redaelli, S; Steinhagen, R; Strzelczyk, M; Tomas, R; Vanbavinckhove, G; Wenninger, J

    2012-01-01

    The Achromatic Telescopic Squeezing (ATS) scheme is a novel squeezing mechanism enabling the production of very low β* in circular colliders. The basic principles of the ATS scheme will be reviewed together with its strong justification for the High-Luminosity LHC Project. In this context, a few dedicated experiments with beam were meticulously prepared and took place at the LHC in 2011. The results obtained will be highlighted, demonstrating the potential of the ATS scheme for any upgrade project relying on a strong reduction of β*.

  20. Discussion on the Five Basic Syndrome Patterns and Their Corresponding Treating Principles and Prescriptions

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Based on the theory of latency system and dominance system and the analytical methods of the four forms and five stages in the development of a disease, this article is to explore the regularity of the five basic patterns of a syndrome to explain the mechanism of its occurrence and development. Different patterns of a syndrome suggest different areas affected and symptoms of a disease. Therefore, different treating principles and prescriptions should be adopted, I.e., 'treating the same syndrome with different methods'.

  1. Teaching Physiology in integrated basic medical sciences – sharing experiences from Nepal.

    Directory of Open Access Journals (Sweden)

    Pradhan AK

    2013-12-01

    Full Text Available Physiology is the basis of the medical profession [1]. Clear understanding of the mechanisms of the body functions always requires a high level of integration, apart from a descriptive approach [2, 3]. I worked as Professor in the Manipal College of Medical Sciences (MCOMS, Pokhara in the year 2009 -2010. Although my stay in Nepal was relatively short period, but the medical education system in Nepal influenced me. In Nepal, a traditional way of teaching pattern which is lecture-based, teacher-centered, discipline-based, examination-driven, and hospital-oriented is followed. Basic sciences and clinical sciences are the two main part of the medical curriculum in Nepal. The Bachelor of Medicine and Bachelor of Surgery degree is a four and half year's program, which is followed by one year internship. A large number of new medical colleges are coming up under Nepal Medical Council guidelines. There is a growing demand of Physicians in Nepal. Currently there are 18 medical colleges under Nepal Medical Council [4]. Manipal College of Medical Sciences is under Kathmandu University, one of the best and leading medical institutes in the country. This medical college is located in Pokhara. Students hailing from Nepal, India, Sri Lanka and other countries attend the four and a half year undergraduate medical (MBBS course. The MBBS course in Nepal is divided into nine semesters. Basic science subjects include Anatomy, Physiology, Biochemistry, Microbiology, Pathology, Pharmacology and Community Medicine which are taught in an integrated manner during the first four semesters (two years period. Community Medicine continues as a part of syllabus till the seventh semester and the clinical subjects like Medicine, Surgery, OBG, Ophthalmology, Orthopedics, Dermatology etc. are taught during the last five semesters of the MBBS course. At present Tribhuvan University (TU, Kathmandu University (KU, BP Koirala Institute of Health Sciences (BPKIHS and NAMS (National

  2. Ocean warming and acidification: Unifying physiological principles linking organism response to ecosystem change?

    Science.gov (United States)

    Pörtner, H. O.; Bock, C.; Lannig, G.; Lucassen, M.; Mark, F. C.; Stark, A.; Walther, K.; Wittmann, A.

    2011-12-01

    The effects of ocean warming and acidification on individual species of marine ectothermic animals may be based on some common denominators, i.e. physiological responses that can be assumed to reflect unifying principles, common to all marine animal phyla. Identification of these principles requires studies, which reach beyond the species-specific response, and consider multiple stressors, for example temperature, CO2 or extreme hypoxia. Analyses of response and acclimation include functional traits of physiological performance on various levels of biological organisation, from changes in the transcriptome to patterns of acid-base regulation and whole animal thermal tolerance. Conclusions are substantiated by comparisons of species and phyla from temperate, Arctic and Antarctic ecosystems and also benefit from the interpretation of paleo-patterns based on the use of a unifying physiological concept, suitable to integrate relevant environmental factors into a more comprehensive picture. Studying the differential specialization of animals on climate regimes and their sensitivity to climate leads to improved understanding of ongoing and past ecosystem change and should then support more reliable projections of future scenarios. For example, accumulating CO2 causes disturbances in acid-base status. Resilience to ocean acidification may be reflected in the capacity to compensate for these disturbances or their secondary effects. Ion and pH regulation comprise thermally sensitive active and passive transfer processes across membranes. Specific responses of ion transporter genes and their products to temperature and CO2 were found in fish, crustaceans and bivalves. However, compensation may cause unfavourable shifts in energy budget and beyond that hamper cellular and mitochondrial metabolism, which are directly linked to the animal's aerobic performance window. In crabs, oysters and, possibly, fishes, a narrowing of the thermal window is caused by moderate increases in

  3. Effects of an additional small group discussion to cognitive achievement and retention in basic principles of bioethics teaching methods

    OpenAIRE

    Dedi Afandi; Yuli Budiningsih; Oktavinda Safitry; Agus Purwadianto; Dwi Novitasari; Ivan R. Widjaja

    2009-01-01

    Aim The place of ethics in undergraduate medical curricula is essential but the methods of teaching medical ethics did not show substantial changes. “Basic principles of bioethics” is the best knowledge to develop student’s reasoning analysis in medical ethics In this study, we investigate the effects of an additional small group discussion in basic principles of bioethics conventional lecture methods to cognitive achievement and retention. This study was a randomized controlled trial with pa...

  4. Effects of an additional small group discussion to cognitive achievement and retention in basic principles of bioethics teaching methods

    Directory of Open Access Journals (Sweden)

    Dedi Afandi

    2009-03-01

    Full Text Available Aim The place of ethics in undergraduate medical curricula is essential but the methods of teaching medical ethics did not show substantial changes. “Basic principles of bioethics” is the best knowledge to develop student’s reasoning analysis in medical ethics In this study, we investigate the effects of an additional small group discussion in basic principles of bioethics conventional lecture methods to cognitive achievement and retention. This study was a randomized controlled trial with parallel design. Cognitive scores of the basic principles of bioethics as a parameter was measured using basic principles of bioethics (Kaidah Dasar Bioetika, KDB test. Both groups were attending conventional lectures, then the intervention group got an additional small group discussion.Result Conventional lectures with or without small group discussion significantly increased cognitive achievement of basic principles of bioethics (P= 0.001 and P= 0.000, respectively, and there were significant differences in cognitive achievement and retention between the 2 groups (P= 0.000 and P= 0.000, respectively.Conclusion Additional small group discussion method improved cognitive achievement and retention of basic principles of bioethics. (Med J Indones 2009; 18: 48-52Keywords: lecture, specification checklist, multiple choice questions

  5. Principles for integrating reactive species into in vivo biological processes: Examples from exercise physiology.

    Science.gov (United States)

    Margaritelis, Nikos V; Cobley, James N; Paschalis, Vassilis; Veskoukis, Aristidis S; Theodorou, Anastasios A; Kyparos, Antonios; Nikolaidis, Michalis G

    2016-04-01

    The equivocal role of reactive species and redox signaling in exercise responses and adaptations is an example clearly showing the inadequacy of current redox biology research to shed light on fundamental biological processes in vivo. Part of the answer probably relies on the extreme complexity of the in vivo redox biology and the limitations of the currently applied methodological and experimental tools. We propose six fundamental principles that should be considered in future studies to mechanistically link reactive species production to exercise responses or adaptations: 1) identify and quantify the reactive species, 2) determine the potential signaling properties of the reactive species, 3) detect the sources of reactive species, 4) locate the domain modified and verify the (ir)reversibility of post-translational modifications, 5) establish causality between redox and physiological measurements, 6) use selective and targeted antioxidants. Fulfilling these principles requires an idealized human experimental setting, which is certainly a utopia. Thus, researchers should choose to satisfy those principles, which, based on scientific evidence, are most critical for their specific research question. PMID:26721187

  6. Basic Principle of Advanced Oxidation Technology : Hybrid Technology Based on Ozone and Titania

    International Nuclear Information System (INIS)

    One of problems in health environment is organic liquid waste from many pollutant resources. Environmental friendly technology for degrading this waste is ozone which produced by plasma discharge technology, but its capability is limited. However, it is needed a new environmental friendly technology which has stronger capability. This new technology is so called advanced oxidation technology. Advanced oxidation technology is a hybrid of ozone, peroxide, UV light and photo catalyst. In this paper, it is introduced basic principle of hybrid of ozone and titania photo catalyst semiconductor. The capability of organic liquid degradation will be stronger because there is new radical which is produced by chemical reaction between electron-hole pair from photo catalyst titania and water or oxygen. This new radical then degrades this organic pollutant. This technology is used to degrade phenol. (author)

  7. Basic legal principles underlying the peaceful uses of nuclear energy in the GDR

    International Nuclear Information System (INIS)

    The central supervisory agency holding many competences in this field is the State Office for Atomic Safety and Radiation Protection (SAAS) of the German Democratic Republic. It is an agency with legal capacity of the Council of Ministers and is headed by the President under the principle of personal management and personal responsibility with collective consultancy in basic issues of atomic safety and radiation protection. The President of the Office is responsible and accountable to the Council of Ministers for supervising and directing his area of duty. He is appointed and dismissed by the Council of Ministers. His comprehensive duties are defined in the 'Statute of the State Office for Atomic Safety and Radiation Protection of the German Democratic Republic - Decision by the Council of Ministers'. (orig./HP)

  8. The RITME method: Basic principles and overview of the LOGARITME concept

    International Nuclear Information System (INIS)

    This paper discusses the basic principles of the RITME method of 3-dimensional reactor core flux and power calculations, and briefly describes the LOGARITME development environment for implementing and managing applications based on the RITME method. RITME is a nodal method for solving the neutron transport equation; it obtains an integral solution in which the fluxes are related to the source terms by precalculated Green functions. The mean flux value per mesh and point flux values are calculated using a library of Green functions computed once and for all by a reference transport code. The carrier and microscopic power distributions can be determined from these flux values. LOGARITME is a computerized environment based on software case (object-oriented analysis aid software utilities) and ADA language. It provides a consistent framework for applications using the RITME method. The general specifications of this environment are described, and potential applications are noted. (author). 3 refs, 1 tab

  9. Introduction of measurement techniques in ultrasonic electronics: Basic principles and recent trends

    Science.gov (United States)

    Mizutani, Koichi; Wakatsuki, Naoto; Ebihara, Tadashi

    2016-07-01

    Measurement — the act of measuring physical properties that we perform — has the potential to contribute to the successful advancement of sciences and society. To open doors in physics and other sciences, various measurement methods and related applications have been developed, and ultrasound has remained a useful probe, power source, and interesting measurement object for the past two centuries. In this paper, we first summarize the basic principles of ultrasound from the viewpoint of measurement techniques for readers who just have started studying or are interested in the field of ultrasonic electronics. Moreover, we also introduce recent studies — ultrasonic properties of materials, measurement techniques, piezoelectric devices, nonlinear acoustics, biomedical ultrasound, and ocean acoustics — and their trends related to measurement techniques in ultrasonic electronics to provide some ideas for related applications.

  10. Basic Principles of Electrical Network Reliability Optimization in Liberalised Electricity Market

    Science.gov (United States)

    Oleinikova, I.; Krishans, Z.; Mutule, A.

    2008-01-01

    The authors propose to select long-term solutions to the reliability problems of electrical networks in the stage of development planning. The guide lines or basic principles of such optimization are: 1) its dynamical nature; 2) development sustainability; 3) integrated solution of the problems of network development and electricity supply reliability; 4) consideration of information uncertainty; 5) concurrent consideration of the network and generation development problems; 6) application of specialized information technologies; 7) definition of requirements for independent electricity producers. In the article, the major aspects of liberalized electricity market, its functions and tasks are reviewed, with emphasis placed on the optimization of electrical network development as a significant component of sustainable management of power systems.

  11. Three-dimensional attached viscous flow basic principles and theoretical foundations

    CERN Document Server

    Hirschel, Ernst Heinrich; Kordulla, Wilhelm

    2014-01-01

    Viscous flow is usually treated in the frame of boundary-layer theory and as a two-dimensional flow. At best, books on boundary layers provide the describing equations for three-dimensional boundary layers, and solutions only for certain special cases.   This book presents the basic principles and theoretical foundations of three-dimensional attached viscous flows as they apply to aircraft of all kinds. Though the primary flight speed range is that of civil air transport vehicles, flows past other flying vehicles up to hypersonic speeds are also considered. Emphasis is put on general three-dimensional attached viscous flows and not on three-dimensional boundary layers, as this wider scope is necessary in view of the theoretical and practical problems that have to be overcome in practice.   The specific topics covered include weak, strong, and global interaction; the locality principle; properties of three-dimensional viscous flows; thermal surface effects; characteristic properties; wall compatibility con...

  12. Basic principles and criteria for public health protection in the event of a nuclear accident

    International Nuclear Information System (INIS)

    Decision making criteria for population protection in nuclear accidents are discussed, and in particular the three basic principles: 1) excluding the appearance of nonstostochastic effects that occur in the case of high individual doses; 2) weighing the risks of radiation damage if such measures are not taken; 3) optimization based on comparison of benefit and costs, using the same measures for costs of health injury to affected populations and of the protected measures to be taken. The decision making criteria developed in Bulgaria are based on international recommendations with lowered upper limit of the range for evacuation and specified doses for vulnerable groups, children and pregnant women. The organization and the specific problems of the following individual types of protective measures are described: sheltering; protection of respiratory organs; iodine prophylaxis; evacuation of the public. One major condition for ensuring protection is to provide the public with timely information on the actual situation and the necessary countermeasures. Such information should be released in a manner that allows for understanding the expediency and significance of actions to be taken. An important aspect of emergency planning consists in taking into consideration the conditions actually prevailing in the country. This is well illustrated in the principle designated as 'national level of challenge' taking into account a country's capabilities for introducing intervention levels and permissible dose levels. In the case of Bulgaria this still remains to be done in protective planning for accidents. (author)

  13. Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling.

    Science.gov (United States)

    Abaci, Hasan Erbil; Shuler, Michael L

    2015-04-01

    Advances in maintaining multiple human tissues on microfluidic platforms has led to a growing interest in the development of microphysiological systems for drug development studies. Determination of the proper design principles and scaling rules for body-on-a-chip systems is critical for their strategic incorporation into physiologically based pharmacokinetic (PBPK)/pharmacodynamic (PD) model-aided drug development. While the need for a functional design considering organ-organ interactions has been considered, robust design criteria and steps to build such systems have not yet been defined mathematically. In this paper, we first discuss strategies for incorporating body-on-a-chip technology into the current PBPK modeling-based drug discovery to provide a conceptual model. We propose two types of platforms that can be involved in the different stages of PBPK modeling and drug development; these are μOrgans-on-a-chip and μHuman-on-a-chip. Then we establish the design principles for both types of systems and develop parametric design equations that can be used to determine dimensions and operating conditions. In addition, we discuss the availability of the critical parameters required to satisfy the design criteria, consider possible limitations for estimating such parameter values and propose strategies to address such limitations. This paper is intended to be a useful guide to the researchers focused on the design of microphysiological platforms for PBPK/PD based drug discovery. PMID:25739725

  14. Contactless inductive flow tomography: basic principles and first applications in the experimental modelling of continuous casting

    Science.gov (United States)

    Stefani, F.; Eckert, S.; Ratajczak, M.; Timmel, K.; Wondrak, T.

    2016-07-01

    Contactless inductive flow tomography (CIFT) aims at reconstructing the flow structure of a liquid metal from the magnetic fields measured at various positions outside the fluid body which are induced by the flow under the influence of one or multiple applied magnetic fields. We recap the basic mathematical principles of CIFT and the results of an experiment in which the propeller-driven three-dimensional flow in a cylindrical had been reconstructed. We also summarize the recent activities to utilize CIFT in various problems connected with the experimental simulation of the continuous casting process. These include flow reconstructions in single-phase and two-phase flow problems in the Mini-LIMMCAST model of slab-casting, studies of the specific effects of an electromagnetic stirrer attached to the Submerged Entry Nozzle (SEN), as well as first successful applications of CIFT on the background of a strong electromagnetic brake field. We conclude by discussing some remaining obstacles for the deployment of CIFT in a real caster.

  15. Dual-Energy CT: Basic Principles, Technical Approaches, and Applications in Musculoskeletal Imaging (Part 2).

    Science.gov (United States)

    Omoumi, Patrick; Verdun, Francis R; Guggenberger, Roman; Andreisek, Gustav; Becce, Fabio

    2015-12-01

    In recent years, technological advances have allowed manufacturers to implement dual-energy computed tomography (DECT) on clinical scanners. With its unique ability to differentiate basis materials by their atomic number, DECT has opened new perspectives in imaging. DECT has been successfully used in musculoskeletal imaging with applications ranging from detection, characterization, and quantification of crystal and iron deposits, to simulation of noncalcium (improving the visualization of bone marrow lesions) or noniodine images. Furthermore, the data acquired with DECT can be postprocessed to generate monoenergetic images of varying kiloelectron volts, providing new methods for image contrast optimization as well as metal artifact reduction. The first part of this article reviews the basic principles and technical aspects of DECT including radiation dose considerations. The second part focuses on applications of DECT to musculoskeletal imaging including gout and other crystal-induced arthropathies, virtual noncalcium images for the study of bone marrow lesions, the study of collagenous structures, applications in computed tomography arthrography, as well as the detection of hemosiderin and metal particles. PMID:26696082

  16. Dual-Energy CT: Basic Principles, Technical Approaches, and Applications in Musculoskeletal Imaging (Part 1).

    Science.gov (United States)

    Omoumi, Patrick; Becce, Fabio; Racine, Damien; Ott, Julien G; Andreisek, Gustav; Verdun, Francis R

    2015-12-01

    In recent years, technological advances have allowed manufacturers to implement dual-energy computed tomography (DECT) on clinical scanners. With its unique ability to differentiate basis materials by their atomic number, DECT has opened new perspectives in imaging. DECT has been used successfully in musculoskeletal imaging with applications ranging from detection, characterization, and quantification of crystal and iron deposits; to simulation of noncalcium (improving the visualization of bone marrow lesions) or noniodine images. Furthermore, the data acquired with DECT can be postprocessed to generate monoenergetic images of varying kiloelectron volts, providing new methods for image contrast optimization as well as metal artifact reduction. The first part of this article reviews the basic principles and technical aspects of DECT including radiation dose considerations. The second part focuses on applications of DECT to musculoskeletal imaging including gout and other crystal-induced arthropathies, virtual noncalcium images for the study of bone marrow lesions, the study of collagenous structures, applications in computed tomography arthrography, as well as the detection of hemosiderin and metal particles. PMID:26696081

  17. Determination of Contact Potential Difference by the Kelvin Probe (Part I) I. Basic Principles of Measurements

    Science.gov (United States)

    Vilitis, O.; Rutkis, M.; Busenberg, J.; Merkulov, D.

    2016-04-01

    Determination of electric potential difference using the Kelvin probe, i.e. vibrating capacitor technique, is one of the most sensitive measuring procedures in surface physics. Periodic modulation of distance between electrodes leads to changes in capacitance, thereby causing current to flow through the external circuit. The procedure of contactless, non-destructive determination of contact potential difference between an electrically conductive vibrating reference electrode and an electrically conductive sample is based on precise control measurement of Kelvin current flowing through a capacitor. The present research is devoted to creation of a new low-cost miniaturised measurement system to determine potential difference in real time and at high measurement resolution. Furthermore, using the electrode of a reference probe, the Kelvin method leads to both the indirect measurement of an electronic work function, or a contact potential of sample, and of a surface potential for insulator type samples. In the article, the first part of the research, i.e., the basic principles and prerequisites for establishment of such a measurement system are considered.

  18. Basic principles and ecological consequences of changing water regimes on nitrogen cycling in fluvial systems.

    Science.gov (United States)

    Pinay, Gilles; Clément, Jean Christophe; Naiman, Robert J

    2002-10-01

    Understanding the environmental consequences of changing water regimes is a daunting challenge for both resource managers and ecologists. Balancing human demands for fresh water with the needs of the environment for water in appropriate amounts and at the appropriate times are shaping the ways by which this natural resource will be used in the future. Based on past decisions that have rendered many freshwater resources unsuitable for use, we argue that river systems have a fundamental need for appropriate amounts and timing of water to maintain their biophysical integrity. Biophysical integrity is fundamental for the formulation of future sustainable management strategies. This article addresses three basic ecological principles driving the biogeochemical cycle of nitrogen in river systems. These are (1) how the mode of nitrogen delivery affects river ecosystem functioning, (2) how increasing contact between water and soil or sediment increases nitrogen retention and processing, and (3) the role of floods and droughts as important natural events that strongly influence pathways of nitrogen cycling in fluvial systems. New challenges related to the cumulative impact of water regime change, the scale of appraisal of these impacts, and the determination of the impacts due to natural and human changes are discussed. It is suggested that cost of long-term and long-distance cumulative impacts of hydrological changes should be evaluated against short-term economic benefits to determine the real environmental costs. PMID:12481915

  19. On a new formulation of microphenomena: Basic principles, stationary fields and beyond

    Indian Academy of Sciences (India)

    Afshin Shafiee

    2011-06-01

    In a series of essays, beginning with this article, we are going to develop a new formulation of microphenomena based on the principles of reality and causality. The new theory provides us with a new depiction of microphenomena assuming a unified concept of information, matter and energy. So, we suppose that in a definite microphysical context (including other interacting particles), each particle is enfolded by a probability field whose existence is contingent on the existence of the particle, but it can locally affect the physical status of the particle in a context-dependent manner. The dynamics of the whole particle-field system obeys deterministic equations in a manner such that when the particle is subjected to a conservative force, the field also experiences a conservative complex force, the form of which is determined by the dynamics of the particle. So, the field is endowed with a given amount of energy, but its value is contingent on the physical conditions the particle is subjected to. Based on the energy balance of the particle and its associated field, we argue why the field has a probabilistic objective nature. The basic elements of this new formulation, its application for some stationary states and its nonlinear generalization for conservative systems are discussed here.

  20. RENEWAL OF BASIC LAWS AND PRINCIPLES FOR POLAR CONTINUUM THEORIES (Ⅷ)-PRINCIPLE OF TOTAL WORK AND ENERGY

    Institute of Scientific and Technical Information of China (English)

    DAI Tian-min

    2005-01-01

    Theoretical incompleteness of the existing conservation laws of energy for polar continuum mechanics is further clarified. For completeness, the principles of total work and energy and of total work and energy of incremental rate type are postulated. Via total variations of the former and the latter of them, the principles of virtual displacement and microrotation & stress and couple stress as well as virtual velocity and angular velocity &stress rate and couple stress rate are immediately obtained, respectively. From these principles all balance equations and boundary conditions for micropolar mechanics are naturally and simultaneously deduced. The essential differences between the nontraditional results obtained in this paper and the existing conservation laws of energy are expounded.

  1. Using the Chemistry of Fireworks to Engage Students in Learning Basic Chemical Principles: A Lesson in Eco-Friendly Pyrotechnics

    Science.gov (United States)

    Steinhauser, Georg; Klapotke, Thomas M.

    2010-01-01

    Fascination with fireworks and pyrotechnics can be used for educational purposes. Several aspects of pyrochemistry such as redox reactions, flame colors, or the theory of combustion can be incorporated in the curriculum to illustrate some basic chemical principles, guaranteeing a lesson that will be engaging and memorable. Beyond classic…

  2. Basic Principles of Organization of the Medium and Thinking Process of the Human in its Conceptual Presentation

    OpenAIRE

    Belov, Yuriy; Rabinovich, Zinoviy

    2008-01-01

    Given in the report conceptual presentation of the main principles of fractal-complexity Ration of the media and thinking processes of the human was formulated on the bases of the cybernetic interpretation of scientific information (basically from neurophysiology and neuropsychology, containing the interpretation giving the best fit to the authors point of view) and plausible hypothesis's, filling the lack of knowledge.

  3. Mathematical physiology

    CERN Document Server

    Sneyd, James

    2009-01-01

    There has been a long history of interaction between mathematics and physiology. This book looks in detail at a wide selection of mathematical models in physiology, showing how physiological problems can be formulated and studied mathematically, and how such models give rise to interesting and challenging mathematical questions. With its coverage of many recent models it gives an overview of the field, while many older models are also discussed, to put the modern work in context. In this second edition the coverage of basic principles has been expanded to include such topics as stochastic differential equations, Markov models and Gibbs free energy, and the selection of models has also been expanded to include some of the basic models of fluid transport, respiration/perfusion, blood diseases, molecular motors, smooth muscle, neuroendrocine cells, the baroreceptor loop, turboglomerular oscillations, blood clotting and the retina. Owing to this extensive coverage, the second edition is published in two volumes. ...

  4. Some aspects of metallurgical assessment of boiler tubes-Basic principles and case studies

    International Nuclear Information System (INIS)

    Microstructural changes in boiler tubes during prolong operation at high temperature and pressure decrease load bearing capacity limiting their useful lives. When the load bearing capacity falls below a critical level depending on operating parameters and tube geometry, failure occurs. In order to avoid such failures mainly from the view point of economy and safety, this paper describes some basic principles behind remaining life assessment of service exposed components and also a few case studies related to failure of a reheater tube of 1.25Cr-0.5Mo steel, a carbon steel tube and final superheater tubes of 2.25Cr-1Mo steel and remaining creep life assessment of service exposed but unfailed platen superheater and reheater tubes of 2.25Cr-1Mo steel. Sticking of fly ash particles causing reduction in effective tube wall thickness is responsible for failure of reheater tubes. Decarburised metal containing intergranular cracks at the inner surface of the carbon steel tube exhibiting a brittle window fracture is an indicative of hydrogen embrittlement responsible for this failure. In contrast, final superheater tube showed that the failure took place due to short-term overheating. The influence of prolong service revealed that unfailed reheater tubes exhibit higher tensile properties than that of platen superheater tubes. In contrast both the tubes at 50 MPa meet the minimum creep rupture properties when compared with NRIM data. The remaining creep life of platen superheater tube as estimated at 50 MPa and 570 deg. C (1058 oF) is more than 10 years and that of reheater tube at 50 MPa and 580 deg. C (1076 oF) is 9 years

  5. Molecular and physiological basic processes in the context of radiation protection

    International Nuclear Information System (INIS)

    The aim of this paper is an attempt to answer the question why accumulated knowledge on molecular basis of biological effects of ionizing radiation have not yet resulted in in sufficiently successful chemical radiation protection. In the past decade experimental results which demonstrated a direct regulatory role of some radicals in the main physiological processes such as vascular tone successfully emphasize the significance of old experimental results (the best protection can be achieved through physiological manipulations) connecting them to new data on free radical evolvement and the application of various free radical scavengers in radiation protection, which represents the most appropriate approach to the problem. (author)

  6. Basic anatomical and physiological data for use in radiological protection: reference values ICRP Publication 89

    Energy Technology Data Exchange (ETDEWEB)

    Valentin, J

    2002-12-01

    This report presents detailed information on age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. These reference values provide needed input to prospective dosimetry calculations for radiation protection purposes for both workers and members of the general public. The purpose of this report is to consolidate and unify in one publication, important new information on reference anatomical and physiological values that has become available since Publication 23 was published by the ICRP in 1975. There are two aspects of this work. The first is to revise and extend the information in Publication 23 as appropriate. The second is to provide additional information on individual variation among grossly normal individuals resulting from differences in age, gender, race, or other factors. This publication collects, unifies, and expands the updated ICRP reference values for the purpose of providing a comprehensive and consistent set of age- and gender-specific reference values for anatomical and physiological features of the human body pertinent to radiation dosimetry. The reference values given in this report are based on: (a) anatomical and physiological information not published before by the ICRP; (b) recent ICRP publications containing reference value information; and (c) information in Publication 23 that is still considered valid and appropriate for radiation protection purposes. Moving from the past emphasis on 'Reference Man', the new report presents a series of reference values for both male and female subjects of six different ages: newborn, 1 year, 5 years, 10 years, 15 years, and adult. In selecting reference values, the Commission has used data on Western Europeans and North Americans because these populations have been well studied with respect to anatomy, body composition, and physiology. When appropriate, comparisons are made between the chosen reference values and data from several Asian

  7. Basic anatomical and physiological data for use in radiological protection: reference values ICRP Publication 89

    International Nuclear Information System (INIS)

    This report presents detailed information on age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. These reference values provide needed input to prospective dosimetry calculations for radiation protection purposes for both workers and members of the general public. The purpose of this report is to consolidate and unify in one publication, important new information on reference anatomical and physiological values that has become available since Publication 23 was published by the ICRP in 1975. There are two aspects of this work. The first is to revise and extend the information in Publication 23 as appropriate. The second is to provide additional information on individual variation among grossly normal individuals resulting from differences in age, gender, race, or other factors. This publication collects, unifies, and expands the updated ICRP reference values for the purpose of providing a comprehensive and consistent set of age- and gender-specific reference values for anatomical and physiological features of the human body pertinent to radiation dosimetry. The reference values given in this report are based on: (a) anatomical and physiological information not published before by the ICRP; (b) recent ICRP publications containing reference value information; and (c) information in Publication 23 that is still considered valid and appropriate for radiation protection purposes. Moving from the past emphasis on 'Reference Man', the new report presents a series of reference values for both male and female subjects of six different ages: newborn, 1 year, 5 years, 10 years, 15 years, and adult. In selecting reference values, the Commission has used data on Western Europeans and North Americans because these populations have been well studied with respect to anatomy, body composition, and physiology. When appropriate, comparisons are made between the chosen reference values and data from several Asian

  8. Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. I. Basic principles and neutron diffraction

    OpenAIRE

    Belička M.; Devínsky F.; Balgavý P.

    2014-01-01

    In our paper, we demonstrate several possibilities of using neutrons in pharmaceutical research with the help of examples of scientific results achieved at our University. In this first part, basic properties of neutrons and elementary principles of elastic scattering of thermal neutrons are described. Results of contrast variation neutron diffraction on oriented phospholipid bilayers with intercalated local anaesthetic or cholesterol demonstrate the potential of this method at determination ...

  9. SPECIALIZED MAPPING OF CRUSTAL FAULT ZONES. PART 1: BASIC THEORETICAL CONCEPTS AND PRINCIPLES

    Directory of Open Access Journals (Sweden)

    K. Zh. Seminsky

    2015-09-01

    Full Text Available Long-term studies of shear zones have included collection of data on fractures showing no indication of displacement which are termed as 'blank' fractures. A method aimed at mapping fault structures and stress fields has been developed on the basis of results of paragenetic analysis of measurements of abundant fractures. The method is termed as 'specialized mapping', firstly, due to its specific structural goal so that to distinguish it from the conventional geological mapping of regions in nature, and, secondly, because of the specific procedure applied to refer to fractures as references to decipher fault-block patterns of natural regions. In Part 1, basic theoretical concepts and principles of specialized mapping are described. Part 2 is being prepared for publication in one of the next issues of the journal; it will cover stages of the proposed method and describe some of the cases of its application.In terms of general organizational principles, specialized mapping is similar to other methods based on structural paragenetic analysis and differs from such methods in types of paragenesises viewed as references to reveal crustal fault zones. Such paragenesises result from stage-by-stage faulting (Fig 2 and Fig. 7 during which stress fields of the 2nd order are regularly changeable within the shear zone. According to combined experimental and natural data, a complete paragenesis of fractures in the shear zone includes a major (1st order fault plane and fractures of other seven types, R, R’, n, n’, t, t’ and T (2nd order (Fig. 4 and Fig 8. At the fracture level, each of them corresponds to a paragenesis including three nearly perpendicular systems of early ruptures (Fig. 1, which are based on two classical patterns of conjugated fractures, one of which is consistent with the position of the fault plane (Fig. 3. Taking into account that strike-slip, reverse and normal faults are similar in terms of mechanics (i.e. they are formed due to

  10. State-dependent and reflex drives to the upper airway: Basic physiology with clinical implications

    OpenAIRE

    Horner, RL; Hughes, SW; Malhotra, A

    2014-01-01

    The root cause of the most common and serious of the sleep disorders is impairment of breathing, and a number of factors predispose a particular individual to hypoventilation during sleep. In turn, obstructive hypopneas and apneas are the most common of the sleep-related respiratory problems and are caused by dysfunction of the upper airway as a conduit for airflow. The overarching principle that underpins the full spectrum of clinical sleep-related breathing disorders is that the sleeping br...

  11. State-dependent and reflex drives to the upper airway: basic physiology with clinical implications

    OpenAIRE

    Horner, Richard L.; Hughes, Stuart W.; Malhotra, Atul

    2013-01-01

    The root cause of the most common and serious of the sleep disorders is impairment of breathing, and a number of factors predispose a particular individual to hypoventilation during sleep. In turn, obstructive hypopneas and apneas are the most common of the sleep-related respiratory problems and are caused by dysfunction of the upper airway as a conduit for airflow. The overarching principle that underpins the full spectrum of clinical sleep-related breathing disorders is that the sleeping br...

  12. Physiologically based pharmacokinetic modeling using microsoft excel and visual basic for applications.

    Science.gov (United States)

    Marino, Dale J

    2005-01-01

    Abstract Physiologically based pharmacokinetic (PBPK) models are mathematical descriptions depicting the relationship between external exposure and internal dose. These models have found great utility for interspecies extrapolation. However, specialized computer software packages, which are not widely distributed, have typically been used for model development and utilization. A few physiological models have been reported using more widely available software packages (e.g., Microsoft Excel), but these tend to include less complex processes and dose metrics. To ascertain the capability of Microsoft Excel and Visual Basis for Applications (VBA) for PBPK modeling, models for styrene, vinyl chloride, and methylene chloride were coded in Advanced Continuous Simulation Language (ACSL), Excel, and VBA, and simulation results were compared. For styrene, differences between ACSL and Excel or VBA compartment concentrations and rates of change were less than +/-7.5E-10 using the same numerical integration technique and time step. Differences using VBA fixed step or ACSL Gear's methods were generally Excel and VBA PBPK model dose metrics differed by no more than -0.013% or -0.23%, respectively, from ACSL results. These differences are likely attributable to different step sizes rather than different numerical integration techniques. These results indicate that Microsoft Excel and VBA can be useful tools for utilizing PBPK models, and given the availability of these software programs, it is hoped that this effort will help facilitate the use and investigation of PBPK modeling. PMID:20021074

  13. Model criterion and basic principles of construction bank data abrasive materials durability

    Directory of Open Access Journals (Sweden)

    О.А. Вишневський

    2006-01-01

    Full Text Available  The generalized model is created and the criterion of an abrasive wear of surfaces of materials is determined at not hard-mounted corpuscles. The principle of construction of a data bank of an abrasive wear resistance of materials of friction units is determined. 

  14. Technology insight: metabonomics in gastroenterology-basic principles and potential clinical applications

    DEFF Research Database (Denmark)

    Bjerrum, Jacob Tveiten; Nielsen, Ole H; Wang, Yulan L;

    2008-01-01

    Metabonomics-the study of metabolic changes in an integrated biologic system-is an emerging field. This discipline joins the other 'omics' (genomics, transcriptomics and proteomics) to give rise to a comprehensive, systems-biology approach to the evaluation of holistic in vivo function. Metabonom...... metabonomics in basic and clinical research, with emphasis on applications in the field of gastroenterology....

  15. Using Video Games to Support Pre-Service Elementary Teachers Learning of Basic Physics Principles

    Science.gov (United States)

    Anderson, Janice; Barnett, Michael

    2011-01-01

    The purpose of this work is to share our findings in using video gaming technology to facilitate the understanding of basic electromagnetism with pre-service elementary teachers. To this end we explored the impact of using a game called "Supercharged!" on pre-service teachers' understanding of electromagnetic concepts compared to students who…

  16. Predicting all-cause mortality from basic physiology in the Framingham Heart Study.

    Science.gov (United States)

    Zhang, William B; Pincus, Zachary

    2016-02-01

    Using longitudinal data from a cohort of 1349 participants in the Framingham Heart Study, we show that as early as 28-38 years of age, almost 10% of variation in future lifespan can be predicted from simple clinical parameters. Specifically, we found diastolic and systolic blood pressure, blood glucose, weight, and body mass index (BMI) to be relevant to lifespan. These and similar parameters have been well-characterized as risk factors in the relatively narrow context of cardiovascular disease and mortality in middle to old age. In contrast, we demonstrate here that such measures can be used to predict all-cause mortality from mid-adulthood onward. Further, we find that different clinical measurements are predictive of lifespan in different age regimes. Specifically, blood pressure and BMI are predictive of all-cause mortality from ages 35 to 60, while blood glucose is predictive from ages 57 to 73. Moreover, we find that several of these parameters are best considered as measures of a rate of 'damage accrual', such that total historical exposure, rather than current measurement values, is the most relevant risk factor (as with pack-years of cigarette smoking). In short, we show that simple physiological measurements have broader lifespan-predictive value than indicated by previous work and that incorporating information from multiple time points can significantly increase that predictive capacity. In general, our results apply equally to both men and women, although some differences exist. PMID:26446764

  17. Fundamental Principles of Human Heredity with Reference to Basic Methods Investigating Transmission of Genetic Traits

    Czech Academy of Sciences Publication Activity Database

    Marván, Richard

    Praha: Karolinum, 2007 - (Bláha, P.; Sussane, C.; Rebato, E.), s. 75-95 ISBN 978-80-246-1338-3 R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : history * principles * transmission of traits * karyotype * mutagenesis * polymorphism * pedigree analysis * twin and adoption studies * behavioural genetics Subject RIV: EB - Genetics ; Molecular Biology

  18. Zebrafish Housing Systems: A Review of Basic Operating Principles and Considerations for Design and Functionality

    OpenAIRE

    Lawrence, Christian; Mason, Timothy

    2012-01-01

    The strategies for housing zebrafish used in biomedical research have evolved considerably over the past three decades. To keep pace with the rapid expansion and development of the zebrafish model system, the field has generally moved from keeping fish at the level of aquarium hobbyist to that of industrialized, recirculating aquaculture. Numerous commercial system vendors now offer increasingly sophisticated housing systems based on design principles that maximize the number of animals that ...

  19. Translating molecular medicine into clinical tools: doomed to fail by neglecting basic preanalytical principles

    Directory of Open Access Journals (Sweden)

    Mannello Ferdinando

    2009-10-01

    Full Text Available Abstract This commentary discusses a study on measurements of matrix metalloproteinase 9 (MMP-9 in serum of pseudoxanthoma elasticum patients recently published in Journal of Molecular Medicine. This study can be considered the typical "obstacle" to effective translational medicine as previously documented in JTM journal. Although serum has been frequently proven as inappropriate sample for determining numerous circulating MMPs, among them MMP-9, there are over and over again studies, as in this case, that measure MMP-9 in serum. Comparative measurements in serum and plasma samples demonstrated higher concentrations for MMP-9 in serum due to the additional release from leukocytes and platelets following the coagulation/fibrinolysis process. From this example it can be concluded that translating basic research discoveries into clinical tools needs a more intensive exchange between basic biomedical research and clinical scientists already in an early stage. Otherwise a lost of translation, as discussed in JTM journal, seems to be inevitable.

  20. UV x-ray free electron lasers through high-gain single pass amplifier: Basic principles and issues

    International Nuclear Information System (INIS)

    The author reviews the basic principles of high gain free electron laser amplifier in single pass configuration for generation of intense, tunable radiation for wavelength shorter than 1,000 angstrom. Two schemes are discussed: for wavelength region between 1,000--100 angstrom, the high gain harmonic generation of a coherent input radiation can be used. For x-ray wavelength as short as a few angstrom, the self-amplified spontaneous emission is currently the only known free electron laser scheme. The author also presents a brief introduction of various key issues in realizing these schemes, which will be discussed in detail in other papers in these proceedings

  1. Neutrons in studies of phospholipid bilayers and bilayer–drug interaction. I. Basic principles and neutron diffraction

    Directory of Open Access Journals (Sweden)

    Belička M.

    2014-12-01

    Full Text Available In our paper, we demonstrate several possibilities of using neutrons in pharmaceutical research with the help of examples of scientific results achieved at our University. In this first part, basic properties of neutrons and elementary principles of elastic scattering of thermal neutrons are described. Results of contrast variation neutron diffraction on oriented phospholipid bilayers with intercalated local anaesthetic or cholesterol demonstrate the potential of this method at determination of their position in bilayers. Diffraction experiments with alkan-1-ols located in the bilayers revealed their influence on bilayer thickness as a function of their alkyl chain length.

  2. Milestones and basic principles of grating-based x-ray and neutron phase-contrast imaging

    International Nuclear Information System (INIS)

    This is a review of the most important milestones in the last ten years of development in the field of grating-based x-ray and neutron imaging. It provides a description of the basic imaging principles of grating-based phase-contrast and dark-field radiography and present some exemplary multimodal radiography results obtained with x-rays and neutrons. Furthermore, it reviews the theory of grating-based quantitative transmission, phase-contrast, and dark-field scattering computed tomography.

  3. Basic strategical principles regarding Romanian power development after the year 2000

    International Nuclear Information System (INIS)

    This study deals with the the basic strategies for long term power planning in Romanian economy taking into account socio-economic factors, refurbishment and restructuring, having in view the requirements of free market economy transition. The main directions of this strategy refer to the development of the present power capacities based on fossil fuel burning and hydroelectric power and also to the development of nuclear power plants based on CANDU type reactors. (author) 3 tabs

  4. High-energy cosmic rays and tests of basic principles of Physics

    Directory of Open Access Journals (Sweden)

    Gonzalez-Mestres L.

    2014-04-01

    Full Text Available With the present understanding of data, the observed flux suppression for ultra-high energy cosmic rays (UHECR at energies above 4.1019 eV can be a signature of the Greisen-Zatsepin-Kuzmin (GZK cutoff or be related to a similar mechanism. But it may also correspond, for instance, to the maximum energies available at the relevant sources. In both cases, violations of special relativity modifying cosmic-ray propagation or acceleration at very high energy can potentially play a role. Other violations of fundamental principles of standard particle physics (quantum mechanics, energy and momentum conservation, vacuum homogeneity and “static” properties, effective space dimensions, quark confinement… can also be relevant at these energies. In particular, UHECR data would in principle allow to set bounds on Lorentz symmetry violation (LSV in patterns incorporating a privileged local reference frame (the “vacuum rest frame”, VRF. But the precise analysis is far from trivial, and other effects can also be present. The effective parameters can be related to Planckscale physics, or even to physics beyond Planck scale, as well as to the dynamics and effective symmetries of LSV for nucleons, quarks, leptons and the photon. LSV can also be at the origin of GZK-like effects. In the presence of a VRF, and contrary to a “grand unification” view, LSV and other violations of standard principles can modify the internal structure of particles at very high energy and conventional symmetries may cease to be valid at energies close to the Planck scale. We present an updated discussion of these topics, including experimental prospects, new potentialities for high-energy cosmic ray phenomenology and the possible link with unconventional pre-Big Bang scenarios, superbradyon (superluminal preon patterns… The subject of a possible superluminal propagation of neutrinos at accelerator energies is also dealt with.

  5. [Physical and physiological principles of calculating vascular resistance in cardiovascular circulation].

    Science.gov (United States)

    Hennig, E

    1992-01-01

    After reconstructive vascular surgery the quality of perfusion and the risk of failure can be predicted, if the distal outflow resistance of the graft is known. The laws of the hydrodynamics for the calculation of flow resistance in tubes are discussed with respect to their validity in the circulatory system. Because of great differences between the physiological realities and the physical assumption, and problems in monitoring some of the parameters of the equations, the calculation of the physiological vascular resistance according to the a.m. laws is not possible. With "Ohms law" of the hydrodynamic the calculation of the outflow resistance distal of a graft is possible if the flow through the bypass and the pressure losses in the outflow bed are known. Easier to perform is the measurement of the pressure-time integral generated by the injection of a standardized volume into the graft and the calculation of the outflow resistance with the help of a microprocessor. PMID:1529426

  6. Ultra-high energy physics and standard basic principles : Do Planck units really make sense ?

    OpenAIRE

    Gonzalez-Mestres, Luis

    2013-01-01

    International audience It has not yet been elucidated whether the observed flux suppression for ultrahigh energy cosmic rays (UHECR) at energies above 4 x 10E19 eV is a signature of the Greisen-Zatsepin-Kuzmin (GZK) cutoff or a consequence of other phenomena. In both cases, violations of the standard fundamental principles of Physics can be present and play a significant role. They can in particular modify cosmic-ray interactions, propagation or acceleration at very high energy. Thus, in a...

  7. Goal Commitments and the content of thoughts and dreams: basic principles

    OpenAIRE

    EricKlinger

    2013-01-01

    A few empirically supported principles can account for much of the thematic content of waking thought, including rumination, and dreams. (1) An individual’s commitments to particular goals sensitize the individual to respond to cues associated with those goals. The cues may be external or internal in the person’s own mental activity. The responses may take the form of noticing the cues, storing them in memory, having thoughts or dream segments related to them, and/or taking action. Noticing m...

  8. Basic principles of laser radiation protection and the state of regulation in SRJ

    International Nuclear Information System (INIS)

    Main hazard from work with lasers is the possibility of eye and skin damage. Secondary hazards consists of ionizing radiation, ozone, pollution of working atmosphere with chemical toxic and biological agents from target and laser, electrical and cryogenic liquid hazard, fire and explosion hazard etc. Basic safety measures are: arrangement of working room, with laser working requirements, permanent laser beam path control. Use of appropriate laser protective eye wears, and all additional protective measures against to secondary laser hazards. Current standards and those which will be issued in our country will in rather good level cover the field of laser radiation protection. (author)

  9. RENEWAL OF BASIC LAWS AND PRINCIPLES FOR POLAR CONTINUUM THEORIES (Ⅰ)-MICROPOLAR CONTINUA

    Institute of Scientific and Technical Information of China (English)

    戴天民

    2003-01-01

    Based on the restudies of existing polar continuum theories rather completesystems of basic balance laws and equations for micropolar continuum theory are presented.In these new systems not only the additional angular momentum, surface moment and bodymoment produced by the linear momentum, surface force and body force, respectively, butalso the additional velocity produced by the angular velocity are considered. The newcoupled balance laws of linear momentum, angular momentum and energy arereestablished. From them the new coupled local and nonlocal balance equatiors arenaturally derived. Via contrast it can be clearly seen that the new results are believed to berather general and complete.

  10. A review of basic principles of fractals and their application to pharmacokinetics.

    Science.gov (United States)

    Marsh, R E; Riauka, T A; McQuarrie, S A

    2008-09-01

    Pharmacokinetic models play a crucial role in analyzing and assessing the results of in vitro and in vivo studies. In this review, comparative analysis of pharmacokinetic models under homogeneous and heterogeneous conditions is performed, placing special focus on the role of fractal theory. The concept of fractals provides a new perspective from which processes occurring in heterogeneous, confined, or poorly mixed environments can be modeled. Following a brief theoretical overview, the applicability of fractals in characterizing anatomical structures and physiological processes as well as the transport and reaction of drugs within the body is discussed. There is significant evidence that drug absorption, distribution, metabolism, and excretion are often anomalous, that is to say their behavior deviates from classical theory, and possible reasons and appropriate models are considered. PMID:18551095

  11. Basic principles of 18F-fluoro-deoxyglucose positron emission tomography

    International Nuclear Information System (INIS)

    Positron emission tomography uses photons to receive regional information about dynamic, physiologic, and biochemical processes in the living body. A positron decay is measured indirectly by the simultaneous registration of both gamma rays created by the annihilation. The event is counted, if two directly opposite located detectors register gamma rays in coincidence. Unfortunately the detectors of a positron emission tomography system do not register only true coincident events. There are also scattered and random coincidences. Different types of positron tomographs are presented and scintillation crystals, which are in use for positron emission tomography are discussed. The 2D- and 3D-acquisition methods are described as well as preprocessing methods, such as correction for attenuation, scatter and dead time. For quantification the relative parameter standard uptake value (SUV) is explained. Finally hybrid systems, such as combined positron emission tomography/computed tomography scanners and the use of computed tomography data for attenuation correction are introduced. (author)

  12. Basic principles of Synchrotron Radiation-Induced X-Ray Fluorescence (SRXRF)

    International Nuclear Information System (INIS)

    The characteristic x rays can be used as powerful analytical tools for qualitative and quantitative determination of the major, minor and trace composition of materials. X Ray Fluorescence (XRF) techniques used for almost four decade to solve many problems in basic, applied science, and in industry. The XRF techniques that were developed initially used crystal spectrometers, and are referred to in literature as Wavelength Dispersive (WD) techniques. These WD techniques are still used in many fields and have the merit of a excellent energy resolution that allows for the analysis of many elements while avoiding the overlapping of some fluorescence peaks. They are also particularly useful in a matrix that produces copious quantities of a particular radiation. The principal disadvantages of a WD system are the low efficiency of crystal and the reduced energy region in which crystal spectrometer can be used. In the 1960's, Solid State Detectors (SSD) were developed with energy resolution such that the Energy Dispersive XRF techniques could be developed. These SSD's overcame some of the limitations of the WD techniques. The most attractive characteristics of the EDXRF techniques are in their intrinsic multielemental and non destructive capabilities. The development of the high intensity, high brilliance Synchrotron Radiation (SR) sources have open the possibility to make microanalyses using the XRF techniques, increasing the interest of the scientific community for these techniques. In this paper the basic concepts of the XRF technique are reviewed taking in account the availability of the new sources of x rays. 32 refs., 7 figs

  13. The principles of burying radioactive waste: basic physical and thermomechanical properties of geological formations

    International Nuclear Information System (INIS)

    After a review of the various types of radioactive wastes (short and long lives), the principles of radioactive waste storage in geologic structures are detailed: water is the main vector of migration so radionuclides are buried at depth within a medium of very low permeability and hydraulic gradient; the geological medium must retain its integrity during all the duration of their activity; its very age is obviously the guarantee of its future, but tectonic movements, erosion, climate must not deteriorate it in any way nor break down its structure. The thermomechanical effects are examined for each host medium such as plastic media (salt, clay) and brittle media (granite, shale) with an estimation of the long term and very long term rheological properties. 4 figs., 1 tab., 21 refs

  14. Basic safety principles of INSAG and their application in radioactive waste management

    International Nuclear Information System (INIS)

    The International Nuclear Safety Advisory Group (INSAG) has, in INSAG-11, attempted to show what safety principles are common to all applications of all sources of radiation. It has been considered that these general principles should apply to all industrial activities. A comparison of INSAG-11 with Article 11 of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management (Joint Convention) shows that the management of radioactive waste is but a special case of industrial activity and follows the same safety rules. The importance of the Joint Convention comes, however, from the fact that it is a politically important document, requiring ratification by the parliaments of the contracting parties. The safe management of radioactive waste implies that five types of issue must be taken into consideration, not only technical and ethical ones, but also socio-political, economic and ecological ones. By comparison, sustainable development in its three dimensions (temporal, spatial and sectorial) has five components (ecology, economics, ethics, socio-politics and technology), just like the safe management of radioactive waste. The consequence of this is that if management is treated as a particular case of sustainable development, it will not be accepted by society. The conclusions are that technology alone can not ensure the safety of radioactive waste management and that society will always give priority to socio-political issues over technological ones. Furthermore, it is crucial that people involved in the management of radioactive waste learn to communicate better and to listen more attentively. Their efforts will only succeed when they incorporate all the components that determine the fabric of our society. (author)

  15. The assessment and measurement of adult life stress: Basic premises, operational principles, and design requirements.

    Science.gov (United States)

    Harkness, Kate L; Monroe, Scott M

    2016-07-01

    Life stress is a central factor in the onset and course of a wide range of medical and psychiatric conditions. Determining the precise etiological and pathological consequences of stress, though, has been hindered by weaknesses in prevailing definitional and measurement practices. The purpose of the current paper is to evaluate the primary strategies for defining and measuring major and minor acute life events, chronic stressors, and daily hassles as informed by 3 basic scientific premises. The first premise concerns the manner in which stress is conceptualized and operationally defined, and specifically we assert that stress measures must not conflate the stress exposure with the stress response. The second premise concerns how stress exposures are measured, and we provide guidelines for optimizing standardized and sensitive indicators of life stress. The third premise addresses the consequences of variations in the procedures for life event measurement with regard to the validity of the research designs employed. We show that life stress measures are susceptible to several sources of bias, and if these potential sources of bias are not controlled in the design of the research, spurious findings may result. Our goal is to provide a useful guide for researchers who consider life stress to be an important factor in their theoretical models of disease, wish to incorporate measures of life stress in their research, and seek to avoid the common pitfalls of past measurement practices. (PsycINFO Database Record PMID:27254487

  16. Ultra-high energy physics and standard basic principles. Do Planck units really make sense?

    Science.gov (United States)

    Gonzalez-Mestres, Luis

    2014-04-01

    It has not yet been elucidated whether the observed flux suppression for ultra-high energy cosmic rays (UHECR) at energies above ≃ 4 x 1019 eV is a signature of the Greisen-Zatsepin-Kuzmin (GZK) cutoff or a consequence of other phenomena. In both cases, violations of the standard fundamental principles of Physics can be present and play a significant role. They can in particular modify cosmic-ray interactions, propagation or acceleration at very high energy. Thus, in a long-term program, UHECR data can hopefully be used to test relativity, quantum mechanics, energy and momentum conservation, vacuum properties... as well as the elementariness of standard particles. Data on cosmic rays at energies ≃ 1020 eV may also be sensitive to new physics generated well beyond Planck scale. A typical example is provided by the search for possible signatures of a Lorentz symmetry violation (LSV) associated to a privileged local reference frame (the "vacuum rest frame", VRF). If a VRF exists, the internal structure of standard particles at ultra-high energy can undergo substantial modifications. Similarly, the conventional particle symmetries may cease to be valid at such energies instead of heading to a grand unification and the structure of vacuum may no longer be governed by standard quantum field theory. Then, the question whether the notion of Planck scale still makes sense clearly becomes relevant and the very grounds of Cosmology can undergo essential modifications. UHECR studies naturally interact with the interpretation of WMAP and Planck observations. Recent Planck data analyses tend to confirm the possible existence of a privileged space direction. If the observed phenomenon turns out to be a signature of the spinorial space-time (SST) we suggested in 1996-97, then conventional Particle Physics may correspond to the local properties of standard matter at low enough energy and large enough distances. This would clearly strengthen the cosmological relevance of UHECR

  17. Innovation-marketing enterprise development of innovation-market orientation: basic principles and modelling aspects

    Directory of Open Access Journals (Sweden)

    V.I. Dubnytsky

    2015-07-01

    Full Text Available The aim of the article. The study is devoted to the solution of the urgent scientific and other problems the development of enterprises in the global economy and the development of the theoretical and methodological aspects of innovative management and marketing of the enterprise development innovation and market orientation on the basis of formation of the system principles of innovative development, marketing management within the processes of globalization. The results of the analysis. It is revealed that one of the main problems for modern Ukrainian enterprises is the preservation of competitiveness and the maintenance of business activity in the conditions of the external environment which is continuously changing. It is shown that the economy of the country which wants to develop in the conditions of innovative orientation and increase of the level of motivation in organizational innovation are the main reason to secure enterprises the conditions for the implementation of innovation-marketing orientation, especially in the framework of international commodity markets. It is proved that the company has the influence on the nonlinear nature for the development of the components of open socio-economic systems. It is revealed that in its activity the enterprise has a high degree of dynamism and variability of the external environment, which contributes to the emergence of new laws for the development and control of nonlinear dissipative media. Also, in the global economy within the geo-space there is a place for ‘the presence of co-evolutional effects”. In the study we have got the characteristic of cases within the framework of the need for innovation-marketing development of the enterprise. The substantive aspects of the strategic approach, which are specified in the principles system of the innovative development management of the enterprise-marketing orientation in the global economy are considered. It is found that formation of the

  18. Goal Commitments and the Content of Thoughts and Dreams: Basic Principles

    Directory of Open Access Journals (Sweden)

    Eric eKlinger

    2013-07-01

    Full Text Available A few empirically supported principles can account for much of the thematic content of waking thought, including rumination, and dreams. (1 An individual’s commitments to particular goals sensitize the individual to respond to cues associated with those goals. The cues may be external or internal in the person’s own mental activity. The responses may take the form of noticing the cues, storing them in memory, having thoughts or dream segments related to them, and/or taking action. Noticing may be conscious or not. Goals may be any desired endpoint of a behavioral sequence, including finding out more about something, i.e., exploring possible goals, such as job possibilities or personal relationships. (2 Such responses are accompanied and perhaps preceded by protoemotional activity or full emotional arousal, the amplitude of which determines the likelihood of response and is related to the value placed on the goal. (3 When the individual is in a situation conducive to making progress toward attaining the goal, the response to goal cues takes the form of actions or operant mental acts that advance the goal pursuit. (4 When circumstances are unfavorable for goal-directed operant behavior, the response remains purely mental, as in mind-wandering and dreaming, but still reflects the content of the goal pursuit or associated content. (5 Respondent responses such as mind-wandering are more likely when the individual is mentally unoccupied with ongoing tasks and less likely the more that is at stake in the ongoing task. The probability of respondent thought is highest during relaxed periods, when the brain’s default-mode network dominates, or during sleep. The article briefly summarizes neurocognitive findings that relate to mind-wandering and evidence regarding adverse effects of mind-wandering on task performance as well as evidence suggesting adaptive functions in regard to creative problem-solving, planning, resisting delay discounting, and

  19. Body diffusion kurtosis imaging: Basic principles, applications, and considerations for clinical practice.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Padhani, Anwar R; Chenevert, Thomas L; Koh, Dow-Mu; De Keyzer, Frederik; Taouli, Bachir; Le Bihan, Denis

    2015-11-01

    Technologic advances enable performance of diffusion-weighted imaging (DWI) at ultrahigh b-values, where standard monoexponential model analysis may not apply. Rather, non-Gaussian water diffusion properties emerge, which in cellular tissues are, in part, influenced by the intracellular environment that is not well evaluated by conventional DWI. The novel technique, diffusion kurtosis imaging (DKI), enables characterization of non-Gaussian water diffusion behavior. More advanced mathematical curve fitting of the signal intensity decay curve using the DKI model provides an additional parameter Kapp that presumably reflects heterogeneity and irregularity of cellular microstructure, as well as the amount of interfaces within cellular tissues. Although largely applied for neural applications over the past decade, a small number of studies have recently explored DKI outside the brain. The most investigated organ is the prostate, with preliminary studies suggesting improved tumor detection and grading using DKI. Although still largely in the research phase, DKI is being explored in wider clinical settings. When assessing extracranial applications of DKI, careful attention to details with which body radiologists may currently be unfamiliar is important to ensure reliable results. Accordingly, a robust understanding of DKI is necessary for radiologists to better understand the meaning of DKI-derived metrics in the context of different tumors and how these metrics vary between tumor types and in response to treatment. In this review, we outline DKI principles, propose biostructural basis for observations, provide a comparison with standard monoexponential fitting and the apparent diffusion coefficient, report on extracranial clinical investigations to date, and recommend technical considerations for implementation in body imaging. PMID:26119267

  20. Plant specific basic principle simulator as a first step to plant specific full scope simulator

    International Nuclear Information System (INIS)

    Nuklearna Elektrarna Krsko (NEK) decided to enhance the quality and scope of initial training of NEK technical personnel, mainly in so called Phase 1 and 2 of training for licensed personnel. This training is a prerequisite for further training on the full scope simulator for future operators and is also given to larger number of engineers, working in different important areas where thorough knowledge of nuclear technology and plant systems is required. Due to that it was decided that plant specific Basis Principle Simulators (BPS) should be developed. The other important reason for such decision was an indication that NEK specific full scope simulator will have to be purchased. Based on that it was concluded that BPS should serve as a good opportunity to learn about the state of the art approaches in the modeling area, to see in which direction development of software in conjunction with state of the art hardware is going and in particular to the extent possible verify the existence of required plant documentation in support BPS and later plant specific full scope simulator. In this paper the scope of NEK BPS simulation, experience in initial data gathering, experience with know-how transfer based on direct involvement of NEK and Izobrazevalni Center za Jedrsko Tehnnologijo (ICJT) personnel in modeling of instrumentation and control will be presented. Lessons learned, particularly in light of coming project for NEK full scope simulator, will also be addressed. The future use of the BPS in the NEK training programs will be described. It can be concluded that due to very complex technology, phase approaches in training of key NEK technical personnel, the development of NEK plant specific BPS is justifiable, regardless of the fact that NEK will also obtain specific full scope simulator. It has to be pointed out that BPS can not be supplement for plant specific full scope simulator, due to number of reasons discussed in the paper. (author)

  1. Effects of different cooling principles on thermal sensation and physiological responses

    DEFF Research Database (Denmark)

    Loomans, Marcel G.L.C.; De Wit, Martin H.; Lichtenbelt, Wouter D. Van Marken;

    2013-01-01

    floor and mixing ventilation, and (6) AC-R-D-F; active cooling through radiation by the floor and displacement ventilation. Though all cases were designed at PMV ≈ 0, subjective data indicate significant differences between the cases. For the prediction of thermal sensation and thermal comfort under non......Applying low exergy cooling concepts in the built environment allows reduction of use of high quality energy sources. Non-uniform thermal conditions, which may occur due to application of lowex systems, can result in discomfort. Two different cooling principles were studied: passive (through...... convection in terms of increased air velocities) and active cooling (through convection or radiation). Furthermore, two different ventilation techniques were included: mixing and displacement ventilation. Ten male subjects (age: 20-29) were exposed to six different cases: (1) PC-C-M; passive cooling through...

  2. Using Video Games to Support Pre-Service Elementary Teachers Learning of Basic Physics Principles

    Science.gov (United States)

    Anderson, Janice; Barnett, Michael

    2011-08-01

    The purpose of this work is to share our findings in using video gaming technology to facilitate the understanding of basic electromagnetism with pre-service elementary teachers. To this end we explored the impact of using a game called Supercharged! on pre-service teachers' understanding of electromagnetic concepts compared to students who conducted a more traditional inquiry oriented investigation of the same concepts. This study was a part of a larger design experiment examining the pedagogical potential of Supercharged! the control group learned through a series of guided inquiry methods while the experimental group played Supercharged! during the laboratory sections of the science course. There was significant difference F(2,134) = 4.8, p effect size of d = 0.72. However, while students in the experimental group performed better than their control group peers, they rated their knowledge of the topic lower than the control group ( M post-control = 3.0, M post-experiment = 2.7), leading to further examination of their laboratory journals. Results of this study show that video games can lead to positive learning outcomes, as demonstrated by the increase in test scores from pre- to post-assessment. Additionally, this study also suggests that a complementary approach, in which video games and hands-on activities are integrated, with each activity informing the other, could be a very powerful technique for supporting student scientific understanding. Further, our findings suggest that video game designers should embed meta-cognitive activities such as reflective opportunities into educational video games to provide scaffolds for students and to reinforce that they are engaged in an educational learning experience.

  3. RENEWAL OF BASIC LAWS AND PRINCIPLES FOR POLAR CONTINUUM THEORIES (Ⅵ)-CONSERVATION LAWS OF MASS AND INERTIA

    Institute of Scientific and Technical Information of China (English)

    戴安民

    2003-01-01

    The purpose is to reestablish the coupled conservation laws, the local conservation equations and the jump conditions of mass and inertia for polar continuum theories. In this connection the new material derivatives of the deformation gradient, the line element, the surface element and the volume element were derived and the generalized Reynolds transport theorem was presented. Combining these conservation laws of mass and inertia with the balance laws of momentum, angular momentum and energy derived in our previous papers of this series, a rather complete system of coupled basic laws and principles for polar continuum theories is constituted on the whole. From this system the coupled nonlocal balance equations of mass, inertia, momentum, angular momentum and energy may be obtained by the usual localization.

  4. Designing health care environments: Part I. Basic concepts, principles, and issues related to evidence-based design.

    Science.gov (United States)

    Cesario, Sandra K

    2009-06-01

    A 2001 Institute of Medicine report captured the nation's attention regarding the dangers that can result from the health care environment. This report, fueled by the need for new facilities to be constructed, led to an explosion of research that now links the physical structure and design of health care facilities to the health and well-being of patients, nurses, other health care workers, and visitors. Continuing nursing education that highlights the importance of evidence-based design has been associated with measurable improvement in health care facilities' clinical outcomes, economic performance, employee productivity, customer satisfaction, and cultural congruency. Three major categories of outcomes can be impacted by evidence-based design: stress reduction, safety, and overall health care quality and ecology. In this article, Part I of a two-part series, the basic concepts, principles, and issues related to evidence-based design are introduced. Part II will describe continuing education programs available for nurses. PMID:19639918

  5. Basic Principles - Chapter 6

    Data.gov (United States)

    National Aeronautics and Space Administration — This chapter described at a very high level some of the considerations that need to be made when designing algorithms for a vehicle health management application....

  6. Basic Economic Principles

    Science.gov (United States)

    Tideman, T. N.

    1972-01-01

    An economic approach to design efficient transportation systems involves maximizing an objective function that reflects both goals and costs. A demand curve can be derived by finding the quantities of a good that solve the maximization problem as one varies the price of that commodity, holding income and the prices of all other goods constant. A supply curve is derived by applying the idea of profit maximization of firms. The production function determines the relationship between input and output.

  7. Study on sodium viewing technique applying sodium gamma-rays emission tomography. Verification of basic principle by analytical investigation

    International Nuclear Information System (INIS)

    To confirm structural integrity of a primary cooling system and in-vessel components in a sodium-cooled fast breeder reactor, monitoring and inspection technique applying Gamma-rays emitted from sodium are proposed. The basic principle is as follows. As radioisotope 24Na decays, photons are emitted and a fraction of these photons penetrate materials. If the number of these photons is counted by radiation detectors, an image of gamma-rays source is reconstructed by a computed tomography technique. In this report, Applicability and problems concerned with the technique are investigated. Main results are as follows: (1) To verify applicability, the technique was analytically investigated based on gamma-rays emitted from sodium coolant in a typical pipe of a primary cooling system. As a result, it was confirmed that the image of gamma-rays source could be reconstructed. (2) A required time to measure in a spatial resolution of about 1mm was investigated in the detection efficiency of 20%. The time was about 4 minutes per section by a thousand detectors in the typical pipe of a primary cooling system. And in a typical steam generator, the time was about 2 days per section by ten thousand detectors. (3) To realize a fluoroscopic inspection system, it is necessary that the principle should be verified by experimental researches. Main equipments of the system are a collimator, radiation detector, scanner, signal processing device and image processing device. As a spatial resolution is decide by the collimator, the shape must be evaluated by experimental researches and analytical investigation. (author)

  8. The enhancement of nuclear safety: Basic principles and approaches to ensure the operation safety of NPP's in Korea

    International Nuclear Information System (INIS)

    Nuclear safety of NPPs should receive the highest priority concerns in any mode of operation because various operational transients can develop into an accident of serious consequence. In most nuclear countries, two-tier approach is commonly adopted to assure the operational safety; (1) various operational and maintenance activities by the utility which has the primary responsibility for the safety of the facility, (2) surveillance and inspection by the government authority which officially confirms the nuclear safety to protect the public from the radiation hazards. The utility has to improve the economy of the plant operation and at the same time has to enhance the safety through the achievement of high quality and reliability in operation and maintenance. The regulatory body, in the meantime, confirms the operational safety through the safety review and inspection activities in the form of preoperational inspection, periodical inspection, daily inspection, special inspection, etc. This paper reviews the basic principles for operation and maintenance of NPP, and the fundamental framework of the roles and responsibilities of the utility and the regulatory body with a view to achieving the operational safety. Also discussed is the regulatory effort in Korea to verify the adequacy of the plant management

  9. The Relationship between Immediate Relevant Basic Science Knowledge and Clinical Knowledge: Physiology Knowledge and Transthoracic Echocardiography Image Interpretation

    Science.gov (United States)

    Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit

    2012-01-01

    Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent…

  10. Discussion on the Development and Perfection of Our Civil Law Basic Principles%议我国民法基本原则的发展及完善

    Institute of Scientific and Technical Information of China (English)

    李海泳

    2011-01-01

    《法国民法典》确立了近代民法的基本原则,而《德国民法典》又将近代民法基本原则发展。民法的基本原则随时间和社会发展不断在调整和完善。中国1986年的《民法通则》所规范的基本原则有局限性和滞后性,应进一步发展和完善。%France civil law gives us the basic principles of the civil law in modern times,German civil law made them better.The basic principles of the civil law is becoming better day by day.In China,the civil law ’s basic principles have many weaknesses.The article discusses the development and perfection of the civil law ’s basic principles these years.

  11. BASIC PRINCIPLES OF CONSTRUCTION OF ECONOMIC MECHANISM OF PROGNOSTICATION AND RAPID REACTING ARE ON EVENT OF «OFFENSIVE OF CRISIS»

    OpenAIRE

    Kolmakova, E.

    2011-01-01

    In the article an author proves that the mechanism of prognostication and rapid reacting is needed on an event «offensive of krizisna», which will be instrumental in the proof functioning of enterprise structures in the period of krizisna. Basic principles over of postoeniya of such mechanism are brought in the article.

  12. Opportunities to Learn in School and at Home: How can they predict students' understanding of basic science concepts and principles?

    Science.gov (United States)

    Wang, Su; Liu, Xiufeng; Zhao, Yandong

    2012-09-01

    As the breadth and depth of economic reforms increase in China, growing attention is being paid to equalities in opportunities to learn science by students of various backgrounds. In early 2009, the Chinese Ministry of Education and Ministry of Science and Technology jointly sponsored a national survey of urban eighth-grade students' science literacy along with their family and school backgrounds. The present study focused on students' understanding of basic science concepts and principles (BSCP), a subset of science literacy. The sample analyzed included 3,031 students from 109 randomly selected classes/schools. Correlation analysis, one-way analysis of variance, and two-level linear regression were conducted. The results showed that having a refrigerator, internet, more books, parents purchasing books and magazines related to school work, higher father's education level, and parents' higher expectation of the education level of their child significantly predicted higher BSCP scores; having siblings at home, owning an apartment, and frequently contacting teachers about the child significantly predicted lower BSCP scores. At the school level, the results showed that being in the first-tier or key schools, having school libraries, science popularization galleries, computer labs, adequate equipment for teaching, special budget for teacher training, special budget for science equipment, and mutual trust between teachers and students significantly predicated higher BSCP scores; and having science and technology rooms, offering science and technology interest clubs, special budget for science curriculum development, and special budget for science social practice activities significantly predicted lower BSCP scores. The implications of the above findings are discussed.

  13. Physiological features of the basic species stability of blossoming lawns in the botanical garden of Oles’ Honchar Dnipropetrovsk National University

    OpenAIRE

    G. A. Zaiyko; U. V. Lykholat

    2010-01-01

    The research of antioxidative enzymes activity of the basic representatives of groundcover plants used for the blossoming lawns design at various stages of their development was carried out. Activity of catalase, peroxydase and polyphenoloxydase was analysed in 26 plant species. It is determined, that one of the basic criteria of plants stability is the level of prooxidative and antioxidative metabolic processes. The features of the enzymes activity of antioxidative complex in studied plants ...

  14. 核损害赔偿的基本原则%The Basic Principles of Nuclear Damage Compensation

    Institute of Scientific and Technical Information of China (English)

    刘风景; 郑建保

    2014-01-01

    核能的和平发展和利用,是20世纪人类最重大的科技成就之一。核电站于上世纪50年代左右开始起步,到本世纪已经达到了商业化发展的水平,成为一种具有吸引力的能源。但是,核能的和平利用在给人类社会带来巨大好处的同时,也伴随着巨大的风险。随着前苏联切尔诺贝利和日本福岛等重大核事故的不断发生,核安全特别是核损害赔偿问题日益引起国际社会的广泛关注。通过对与核损害赔偿有关的国际公约和各国国内法进行系统整理,总结出核损害赔偿的基本原则,可为我国制定《核安全法》提供有益的经验。%Utilizing and developing nuclear energy peacefully is a great scientiifc achievement for human in 20th Century. For instance, nuclear energy station, which launched in the last 50 years of 20th Century. has reached a common application in business this century and utilizing of nuclear energy beneifts human a lot. however, it also brings great risks. With the serious nuclear accidents happened in Chernobyl, the former Soviet Union and Fukushima, Japan, nuclear security, especially nuclear damage compensation continually arouses more attention from international community. In view of this, it is necessary to summarize the basic principles of nuclear damage compensation, which will contribute to the making of the Nuclear security law of China.

  15. Perspectives for Developing New Tuberculosis Vaccines Derived from the Pathogenesis of Tuberculosis: I. Basic Principles, II. Preclinical Testing, and III. Clinical Testing

    OpenAIRE

    Bappaditya Dey; Dannenberg, Arthur M.

    2013-01-01

    Part I. Basic Principles. TB vaccines cannot prevent establishment of the infection. They can only prevent an early pulmonary tubercle from developing into clinical disease. A more effective new vaccine should optimize both cell-mediated immunity (CMI) and delayed-type hypersensitivity (DTH) better than any existing vaccine. The rabbit is the only laboratory animal in which all aspects of the human disease can be reproduced: namely, the prevention of most primary tubercles, the arrestment of ...

  16. Continuous education system development principles determining the social phenomenon of its sustainable development at the basic educational level

    OpenAIRE

    Sukhodimtseva Anna Petrovna

    2015-01-01

    This article is about the importance of the implementation of principles of the continuous education system’s development, defining the social phenomenon of sustainable development at the level of general education.

  17. Principles of musical acoustics

    CERN Document Server

    Hartmann, William M

    2013-01-01

    Principles of Musical Acoustics focuses on the basic principles in the science and technology of music. Musical examples and specific musical instruments demonstrate the principles. The book begins with a study of vibrations and waves, in that order. These topics constitute the basic physical properties of sound, one of two pillars supporting the science of musical acoustics. The second pillar is the human element, the physiological and psychological aspects of acoustical science. The perceptual topics include loudness, pitch, tone color, and localization of sound. With these two pillars in place, it is possible to go in a variety of directions. The book treats in turn, the topics of room acoustics, audio both analog and digital, broadcasting, and speech. It ends with chapters on the traditional musical instruments, organized by family. The mathematical level of this book assumes that the reader is familiar with elementary algebra. Trigonometric functions, logarithms and powers also appear in the book, but co...

  18. Brain Basics

    Medline Plus

    Full Text Available ... the anatomy, physiology, and chemistry of the nervous system. When the brain cannot effectively coordinate the billions ... basic working unit of the brain and nervous system. These cells are highly specialized for the function ...

  19. Discussion of basic principles of nuclear part of power generation in Czechoslovakia in the 90's and after the year 2000

    International Nuclear Information System (INIS)

    The publication summarizes the discussion of the basic principles of Czechoslovak power policy in the 1990's and beyond; the authors of the contributions are specialists from all walks of Czechoslovak science, economy, industries, educational institutions, etc. All positive and negative aspects of the present and future situation in Czechoslovak power generation were debated. It was suggested that in future, one of the four concepts on which Czechoslovak nuclear power is based should be implemented: Soviet type WWER nuclear power plants (basic programme); WWER type reactors of an improved Czechoslovak design (intellectualization of the basic programme); foreign reactors (LWR) with the maximum possible participation of Czechoslovak industry and civil engineering (application programme); and medium power nuclear facilities of a modular design with the participation of Czechoslovak industry and civil engineering after 2000 (development programme). (P.A.)

  20. Basic principles of economic law reflected in Tsunzi’s thought%荀子思想所体现的经济法基本原则

    Institute of Scientific and Technical Information of China (English)

    韩卫平

    2011-01-01

    Some theories in Tsunzi's thought are to a certain extent consistent with basic principles of modern economic law.The thought of "all fairness means no fairness" embodies fairness principle,"both interest and justice"the society-oriented principle,"value on ritual and law"the appropriate government intervention principle,and"reasonable measurement and distribution"the sustainable devel-opment principle of economic law.%荀子思想中的有关理论与中国现代经济法所体现的基本原则有相当的一致性:其"维齐非齐"的思想体现了经济法的平原则,其"义利两有"思想体现了经济法的社会本位原则,其"隆礼重法"思想体现了经济法的国家适度干预原则,其"度量分界"思想体现了经济法的可持续发展原则。

  1. Analyzing the basic principles of tissue microarray data measuring the cooperative phenomena of marker proteins in invasive breast cancer

    OpenAIRE

    Korsching, Eberhard; Buerger, Horst; Boecker, Florian; Packeisen, Jens; Agelopoulos, Konstantin; Poos, Kathrin; Nadler, Walter

    2013-01-01

    Background: The analysis of a protein-expression pattern from tissue microarray (TMA) data will not immediately give an answer on synergistic or antagonistic effects between the observed proteins. But contrary to apparent first impression, it is possible to reveal those cooperative phenomena from TMA data. The data is (1) preserving a lot of the original physiological information content and (2) because of minor variances between the tumor samples, contains several related slightly different ...

  2. Determination of the standards of the thermo-physiological tolerance for working in basic nuclear installation in TIVA protective clothing

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the duration limited exposure (DLE) for working in a contaminated zone in a basic nuclear installation using the new ventilated TIVA protective clothing. Five subjects underwent a treadmill exercise (3.5 km/h, 3% of slope) of up to 2 h in a climatic chamber at 25, 35, and 45 deg. C. Cardiac frequency, rectal temperature and skin temperature were continuously recorded. The dehydration level was measured by the loss of weight during the exercise. At 25 deg. C, thermal and cardiovascular thresholds are not reached; the risk is dehydration if the exercise is prolonged. In contrast, the thresholds for Tre at 39 deg. C (97 ± 29 and 69 ± 28 min for 35 and 45 deg. C, respectively) and for the increase in Tre (+1.5 deg. C) are reached earlier (84 ± 38 min and 57 ± 21 min at 35 and 45 deg. C, respectively). This leads to a higher heat storage (42.2 ± 22.9 W/m2 and 63.7 ± 29.4 W/m2, at 35 and 45 deg. C, respectively), which constitutes a higher risk of heat illnesses. The dehydration level is 2% of the weight for the tests at 35 and 45 deg. C. As a consequence, DLE for working in a contaminated zone in a basic nuclear installation in environmental conditions and using the new ventilated TIVA protective clothing, as encountered in our experiments, are proposed to avoid hyperthermic accidents. (authors)

  3. The rights of shareholders – basic principle of corporate governance by means of case-specific jurisprudence

    OpenAIRE

    Adrian Doru BÎGIOI; Cristina Elena DUMITRU

    2016-01-01

    Respecting shareholders’ rights represents one of the fundamental principles of corporate governance, underpinning the establishment of economic entities, as a form of association of individuals and / or legal entities in order to carry out profit-oriented activities. However, there are situations in which the management, the other shareholders, or even the authorities, do not respect certain shareholders’ rights, leading to a number of negative effects, such as the closing of companies. Bas...

  4. TU-A-18A-01: Basic Principles of PET/CT, Calibration Methods and Contrast Recovery Across Multiple Cameras

    Energy Technology Data Exchange (ETDEWEB)

    Kappadath, S [UT MD Anderson Cancer Center, Houston, TX (United States); Nye, J [Emory University, Atlanta, GA (United States)

    2014-06-15

    This continuing education session will discuss the physical principles of PET/CT imaging and characterization of contrast recovery using accreditation phantoms. A detailed overview will be given on the physical principles of PET including positron decay physics, 2D and 3D data acquisition, time-of-flight, scatter correction, CT attenuation correction, and image reconstruction. Instrument quality control and calibration procedures will be discussed. Technical challenges, common image artifacts and strategies to mitigate these issues will also be discussed. Data will be presented on acquisition techniques and reconstruction parameters affecting contrast recovery. The discussion will emphasize the minimization of reconstruction differences in quantification metrics such as SUV and contrast recovery coefficients for the NEMA and ACR clinical trial phantoms. Data from new and older generation scanners will be shown including comparison of contrast recovery measurements to their analytical solutions. The goal of this session is to update attendees on the quality control and calibration of PET/CT scanners, on methods to establish a common calibration for PET/CT scanners to control for instrument variance across multiple sites. Learning Objectives: Review the physical principles of PET/CT, quality control and calibration Gain further understanding on how to apply techniques for improving quantitative agreement across multiple cameras Describe the differences between measured and expected contrast recovery for the NEMA and ACR PET phantoms.

  5. TU-A-18A-01: Basic Principles of PET/CT, Calibration Methods and Contrast Recovery Across Multiple Cameras

    International Nuclear Information System (INIS)

    This continuing education session will discuss the physical principles of PET/CT imaging and characterization of contrast recovery using accreditation phantoms. A detailed overview will be given on the physical principles of PET including positron decay physics, 2D and 3D data acquisition, time-of-flight, scatter correction, CT attenuation correction, and image reconstruction. Instrument quality control and calibration procedures will be discussed. Technical challenges, common image artifacts and strategies to mitigate these issues will also be discussed. Data will be presented on acquisition techniques and reconstruction parameters affecting contrast recovery. The discussion will emphasize the minimization of reconstruction differences in quantification metrics such as SUV and contrast recovery coefficients for the NEMA and ACR clinical trial phantoms. Data from new and older generation scanners will be shown including comparison of contrast recovery measurements to their analytical solutions. The goal of this session is to update attendees on the quality control and calibration of PET/CT scanners, on methods to establish a common calibration for PET/CT scanners to control for instrument variance across multiple sites. Learning Objectives: Review the physical principles of PET/CT, quality control and calibration Gain further understanding on how to apply techniques for improving quantitative agreement across multiple cameras Describe the differences between measured and expected contrast recovery for the NEMA and ACR PET phantoms

  6. Basic equations of the quasiparticle-phonon nuclear model with the effects due to the Pauli principle and the phonon ground state correlations

    International Nuclear Information System (INIS)

    A system of basic equations of the quasiparticle-phonon model is obtained for energies and a structure of excited states described by the wave functions containing one- and two-phonon components. The effects due to the Pauli principle for two-phonon components and the phonon ground state correlations of a spherical nucleus are taken here into account. The quantitative estimations of these effects are given by a simplified scheme. The relation between these equations with the results from other theoretical approaches is discussed

  7. Basic Guiding Principles of Courseware Facture for%职业院校教学课件制作的基本指导原则

    Institute of Scientific and Technical Information of China (English)

    龙军

    2014-01-01

    多媒体课件制作是职业技术院校课程改革中的重要内容,本文阐述了在职业技术教育中多媒体课件制作的基本指导原则,这些原则来自于现代教育理论,教育心理学和教学实践。%This article discusses some basic principles followed in courseware facture under the environment of innovation education based on modern educational theory ,educational psychology.

  8. Basic principles and applications of 18F-FDG-PET/CT in oral and maxillofacial imaging: A pictorial essay

    International Nuclear Information System (INIS)

    A combination of positron emission tomography (PET) with 18F-labeled fluoro-2-deoxyglucose (18F-FDG) and computed tomography (18F-FDG-PET/CT) has increasingly become a widely used imaging modality for the diagnosis and management of head and neck cancer. On the basis of both recent literature and our professional experience, we present a set of principles with pictorial illustrations and clinical applications of FDG-PET/CT in the evaluation and management planning of squamous cell carcinoma of the oral cavity and oropharynx. We feel that this paper will be of interest and will aid the learning of oral and maxillofacial radiology trainees and practitioners.

  9. RENEWAL OF BASIC LAWS AND PRINCIPLES FOR POLAR CONTINUUM THEORIES (Ⅱ)-MICROMORPHIC CONTINUUM THEORY AND COUPLE STRESS THEORY

    Institute of Scientific and Technical Information of China (English)

    戴天民

    2003-01-01

    The purpose is to reestablish the balance laws of momentum, angular momentumand energy and to derive the corresponding local and nonlocal balance equations formicromorphic continuum mechanics and couple stress theory. The desired results formicromorphic continuum mechanics and couple stress theory are naturally obtained via directtransitions and reductions from the coupled conservation law of energy for micropolarcontinuum theory, respectively. The basic balance laws and equation s for micromorphiccontinuum mechanics and couple stress theory are constituted by combining these resultsderived here and the traditional conservation laws and equations of mass and microinertiaand the entropy inequality. The incomplete degrees of the former related continuum theoriesare clarified. Finally, some special cases are conveniently derived.

  10. Basic principles and applications of {sup 18}F-FDG-PET/CT in oral and maxillofacial imaging: A pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Omami, Galal [Dept. of Oral Diagnosis and Polyclinics, Faculty of Dentistry, The Hong Kong University, Hong Kong (Hong Kong); Tamimi, Dania [BeamReaders Inc., Orlando (United States); Branstette, Barton F. [Dept. of Otolaryngology and Radiology, University of Pittsburgh School of Medicine, Pittsburgh (United States)

    2014-12-15

    A combination of positron emission tomography (PET) with 18F-labeled fluoro-2-deoxyglucose ({sup 18}F-FDG) and computed tomography ({sup 18}F-FDG-PET/CT) has increasingly become a widely used imaging modality for the diagnosis and management of head and neck cancer. On the basis of both recent literature and our professional experience, we present a set of principles with pictorial illustrations and clinical applications of FDG-PET/CT in the evaluation and management planning of squamous cell carcinoma of the oral cavity and oropharynx. We feel that this paper will be of interest and will aid the learning of oral and maxillofacial radiology trainees and practitioners.

  11. Basic principles and application to shape children’s good behavior%塑造儿童良好行为的基本原理及应用

    Institute of Scientific and Technical Information of China (English)

    李廷玉

    2013-01-01

    中国正处于二代独生子女时代,儿童良好行为塑造成为家长关注热点,行为受多种因素的影响,与气质、认知局限性、自我为中心思维方式、语言发育、父母的行为及家庭环境、甚至当地的文化等有很大的关系。应用行为改变的基本原理及技术,用较多的实例讲述了条件反射与操作性条件反射原理及应用,介绍了实际生活中塑造儿童行为的两个基本原则及应用实例,希望对儿科医生指导家长有所裨益。%China is in the era of second generation of one-child. How to shape children’s good behavior becomes the hot issue of parents’ concern. Behavior is influenced by a variety of factors , such as temperament , cognitive limita-tions, self-centered thinking, language development, parent behavior, family environment, and local culture. This paper adopts basic principles and technology of behavior change to illustrate the principle and application of conditioned reflex and operant conditioning reflection. It also introduces two basic principles and application examples for shaping children’s behavior in real life to provide guidance for pediatricians and parents.

  12. Basic principles of legal protection with regard to the intraorganisational rights and duties of corporate bodies and their organs

    International Nuclear Information System (INIS)

    While the foundations of disputes concerning the rights and duties of organs under constitutional order are laid down in the Basic Law and in the constitutional order, the dispute concerning the rights and duties of organs under administrative law has been elaborated by administrative jurisdiction and legal science. The author treats major aspects in form of theses. They have to be considered in the formal and material preparation of problems and in the (administrative-) procedural transfer of problems. Competencies assigned to the organs of corporate bodies may be understood as subjective public rights. To open up legally the inner circle of law would not bring about suability automatically. Special circumstances alone would lead to a suable revalorization of competence assignments, as in disputes concerning the rights and duties of organs pertaining to communities, group universities and broadcasting companies. (HSCH)

  13. The rights of shareholders – basic principle of corporate governance by means of case-specific jurisprudence

    Directory of Open Access Journals (Sweden)

    Adrian Doru BÎGIOI

    2016-04-01

    Full Text Available Respecting shareholders’ rights represents one of the fundamental principles of corporate governance, underpinning the establishment of economic entities, as a form of association of individuals and / or legal entities in order to carry out profit-oriented activities. However, there are situations in which the management, the other shareholders, or even the authorities, do not respect certain shareholders’ rights, leading to a number of negative effects, such as the closing of companies. Based on these considerations, in this paper, we set as research objective to analyze the circumstances, which may affect shareholders’ rights. To meet the research objectives, we analyzed the case-specific jurisprudence published by the courts of law till 31st of December 2015. The results of the study show that the shareholders’ rights, which are not respected, include: the property right, the right to receive dividends, the right to participate and vote in the general assemblies of shareholders, the right to be elected in the governing bodies, and not the least, the most important one in accounting terms, the right to be informed.

  14. Integrating microbial physiology and physiochemical principles in soils with the MIcrobial-MIneral Carbon Stabilization (MIMICS model

    Directory of Open Access Journals (Sweden)

    W. R. Wieder

    2014-01-01

    Full Text Available Previous modeling efforts document divergent responses of microbial explicit soil biogeochemistry models when compared to traditional models that implicitly simulate microbial activity, particularly following environmental perturbations. However, microbial models are needed that capture current soil biogeochemical theories emphasizing the relationships between litter quality, functional differences in microbial physiology, and the physical protection of microbial byproducts in forming stable soil organic matter (SOM. To address these limitations we introduce the MIcrobial-MIneral Carbon Stabilization (MIMICS model. In MIMICS, the turnover of litter and SOM pools are governed by temperature sensitive Michaelis–Menten kinetics and the activity of two physiologically distinct microbial functional types. The production of microbial residues through microbial turnover provides inputs to SOM pools that are considered physically or chemically protected. Soil clay content determines the physical protection of SOM in different soil environments. MIMICS adequately simulates the mean rate of leaf litter decomposition observed at a temperate and boreal forest sites, and captures observed effects of litter quality on decomposition rates. Initial results from MIMICS suggest that soil C storage can be maximized in sandy soils with low-quality litter inputs, whereas high-quality litter inputs may maximize SOM accumulation in finely textured soils that physically stabilize microbial products. Assumptions in MIMICS about the degree to which microbial functional types differ in the production, turnover, and stabilization of microbial residues provides a~mechanism by which microbial communities may influence SOM dynamics in mineral soils. Although further analyses are needed to validate model results, MIMICS allows us to begin exploring theoretical interactions between substrate quality, microbial community abundance, and the formation of stable SOM.

  15. Protein standardization III: Method optimization basic principles for quantitative determination of human serum proteins on automated instruments based on turbidimetry or nephelometry.

    Science.gov (United States)

    Blirup-Jensen, S

    2001-11-01

    Quantitative protein determinations in routine laboratories are today most often carried out using automated instruments. However, slight variations in the assay principle, in the programming of the instrument or in the reagents may lead to different results. This has led to the prerequisite of method optimization and standardization. The basic principles of turbidimetry and nephelometry are discussed. The different reading principles are illustrated and investigated. Various problems are identified and a suggestion is made for an integrated, fast and convenient test system for the determination of a number of different proteins on the same instrument. An optimized test system for turbidimetry and nephelometry should comprise high-quality antibodies, calibrators, controls, and buffers and a protocol with detailed parameter settings in order to program the instrument correctly. A good user program takes full advantage of the optimal reading principles for the different instruments. This implies--for all suitable instruments--sample preincubation followed by real sample blanking, which automatically corrects for initial turbidity in the sample. Likewise it is recommended to measure the reagent blank, which represents any turbidity caused by the antibody itself. By correcting all signals with these two blank values the best possible signal is obtained for the specific analyte. An optimized test system should preferably offer a wide measuring range combined with a wide security range, which for the user means few re-runs and maximum security against antigen excess. A non-linear calibration curve based on six standards is obtained using a suitable mathematical fitting model, which normally is part of the instrument software. PMID:11831625

  16. Geriatrics and radiation oncology. Pt. 1. How to identify high-risk patients and basic treatment principles

    International Nuclear Information System (INIS)

    Background: Until the mid of this century, 33% of the Western population will be ≥ 65 years old. The percentage of patients being ≥ 80 years old with today 5% will triple until 2050. Therefore, radiation oncologists must be familiar with special geriatric issues to meet the increasing demand for multidisciplinary cooperation and to offer useful and individual treatment concepts. Patients and Methods: This review article will provide basic data on the definition, identification and treatment of geriatric cancer patients. Results: The geriatric patient is defined by typical multimorbidity (15 items) and by age-related increased vulnerability. Best initial identification of geriatric patients will be provided by assessment including the Barthel Index evaluating self-care and activity in daily life, by the Mini-Mental Status Test that will address cognitive pattern, and by the Timed 'Up and Go' Test for evaluation of mobility. As for chemotherapy, standard treatment was associated with increased toxicity, consequently, dose modifications and supportive treatment are of special importance. Conclusion: Geriatric cancer patients need to be identified by special assessment instruments. Due to increased toxicity following chemotherapy, supportive measures seem important. Radiation treatment as a noninvasive and outpatient-based treatment remains an important and preferable option. (orig.)

  17. The requirements and basic principles of the system of radiation monitoring of the environment to ensure radiation safety in the republic of Belarus

    International Nuclear Information System (INIS)

    For the Republic of Belarus, the problem of radiation safety is one of the most important tasks of ensuring national security. In this regard, development of a framework methodology management radio-logical monitoring of the environment is an important scientific challenge both in terms of retrospective assessment of the effectiveness of radiation monitoring in the period 1963–2011 years and in terms of the proposed activity, in the first place, the construction of nuclear power (NPP) in Belarus. The article presents the conceptual framework of radiation monitoring, data analysis of internal and external sources of threats and risks of radiation safety, assessed their dynamics. described signs of a problem situation and ways to resolve it. Formulated system requirements and basic principles of radiation monitoring system and its programs. A model of radiation monitoring as an essential part of the complex operational and long-term measures for preventing and managing risks, challenges and threats of radiation safety. (authors)

  18. Application of the Principles of Social Demand Approach (SDA in the Implementation of Universal Basic Education (UBE In Nigeria: A Sociological Analysis

    Directory of Open Access Journals (Sweden)

    DR. IBIA E. IBIA

    2014-02-01

    Full Text Available The Universal Basic Education (UBE was launch in 1999 to replace the failed Universal Primary Education (UPE of the 1970s. The focus of UBE is to take education to the doorsteps of all Nigerians. Inspired by the relative tag on Nigeria as a country where nothing work, the study was carried out with much reliance on secondary sources of data and observation pivoted by Robert Merton’s version of the functional theory. We assert that although the ideals of UBE are lofty, it could fail as the previous UPE programme. To stem the tide, we suggests the application of the principles of Social Demand Approach (SDA which exposes the essential conditions that must be met before a high level of success of UBE can be guaranteed. We recommend accurate demographic data, proper funding, stiff penalty against destructive elements and assurance of quality among others. We conclude that educational problems are artificial and in man lies the solution.

  19. Principles of macro-methodic of junior female gymnasts’ training to sport exercises for gymnastic all round competitions at specialized basic stage

    Directory of Open Access Journals (Sweden)

    Potop V.A.

    2015-08-01

    Full Text Available Purpose: working out of principles of junior female gymnasts’ macro-methodic training to sport exercises for all round competitions at stage of specialized basic training. Material: in the research 19 girl-gymnasts from reserve of combined team of Romania participated. Measurements and assessment of technical fitness at training sessions and in conditions of competitions were conducted at 120 training sessions (10 sessions a week. Results: we worked out and realized experimentally and in training sessions principles of macro-methodic training to gymnastic exercises. Macro-methodic of training is presented in structure of long-term programs of training for all round competitions. Macro-methodic is presented as combination of elements of motor, technical, didactic and technological structures of sport exercises (in the present article it was described on material of vaults of Yurchenko’s type. Conclusions: macro-methodic permits to state optimal algorithm of mastering of theoretical and practical materials at training sessions. Besides, it permits to demonstrate steady growth of sport results at competitions. With it individual-age features of junior female gymnasts, tendencies and specialists’ requirements are considered.

  20. 萨克斯呼吸的生理原理探究%Sax physiological principle of breathing

    Institute of Scientific and Technical Information of China (English)

    许锴

    2015-01-01

    根据西洋乐器的分类方法,萨克斯是一种木管乐器,呼吸是提供其发音的唯一动力,没有气息,萨克斯就无法变成真正的"乐器".同时,气息也是学习萨克斯过程中非常难把握的一个要素,气息的好坏对萨克斯的演奏有着直接的影响.掌握了正确的呼吸方法,气息的练习就会事倍功半.本文笔者在结合萨克斯的基本演奏的基础上,对萨克斯演奏过程中的气息原理、呼吸方法和演奏技巧进行论述,探究如何运用呼吸才可以使萨克斯演奏出好的音色.%According to the classification of Western musical instruments, saxophone is a woodwind instrument, the breath is provide the only motive of the pronunciation, no breath Sachs wil not become real "instruments." At the same time, the breath is also a factor that is very difficult to grasp in the process of learning Sax, the quality of the atmosphere has a direct impact on the performance of Sax. Master the correct breathing, breathing exercises wil be less effective. In this paper, the author on the basis of combination of saxophone playing. Saxophone playing in the process of breath principle, respiration and playing skils are discussed, explore how to use breathing can make saxophone playing the sound.

  1. Discussion on the Basic Principles of Credit Information Collection and Application%信用信息收集和使用的基本原则探讨

    Institute of Scientific and Technical Information of China (English)

    孙志伟

    2015-01-01

    The basic principle for credit information collection and application is not only for the need of protecting the rights and interests of information subjects, but also for the need of standardizing related agencies’ business in credit industry.The principles for protecting personal privacy and guaranteeing fairness are the most fundamental;these require that the information referring to individual privacy and affecting fair credit-granting cannot be collected at random, and further more cannot be used as a variable for personal credit evaluation models.The principle of evi-dence will normalize the behavior of agencies that collect and preserve personal credit information, and prevent the arbitrary collection of personal information.The principle of right-to-know is the guarantee for the information sub-jects to know which credit information is collected.The principle of negative-behavior-noticing is aimed at more neg-ative sensitive information.The principle of right-to-objection is the necessity to maintain the accuracy of credit in-formation.The implementation of the principles needs the cooperation of institutions that collect and preserve infor-mation with credit-granting institutions, and should be their legal obligations.%信用信息收集和使用的基本原则既是保护信息主体权益的需要,也是规范信用行业相关机构业务的需要。保护个人隐私和保障公平的原则最为根本,该原则要求那些纳入个人隐私和影响公平授信的信息不能随意被搜集,更不能作为个人信用评估模型的变量。证据原则能规范搜集与保存个人信用信息的机构行为,防止任意搜集个人信息。知情权原则是对信息主体了解那些信用信息被搜集的保障。不利行为通知原则针对的是更为敏感的负面信息。异议权原则是维护信用信息准确性之必需。这些原则的贯彻更需要搜集和保存信用信息专业机构、授信

  2. Basic hydraulics

    CERN Document Server

    Smith, P D

    2013-01-01

    BASIC Hydraulics aims to help students both to become proficient in the BASIC programming language by actually using the language in an important field of engineering and to use computing as a means of mastering the subject of hydraulics. The book begins with a summary of the technique of computing in BASIC together with comments and listing of the main commands and statements. Subsequent chapters introduce the fundamental concepts and appropriate governing equations. Topics covered include principles of fluid mechanics; flow in pipes, pipe networks and open channels; hydraulic machinery;

  3. Nutrition in sport - basic principles

    OpenAIRE

    Handziski, Zoran

    2013-01-01

    Sports medicine is a clinical and academic medical specialization that deal with promotion and stimulation of physical active way of leaving and diagnosing, medical treatment, prevention and rehabilitation of injuries and diseases acquired by physical activity, exercising and sport on any level. The sports medicine deals with prescription of dosed exercises (volume, intensity and frequency) in prevention and medical treatment of diseases (cardiovascular, degenerative, metabolic, malignant...

  4. Portuguese intermunicipal organization - Basic principles

    OpenAIRE

    Alves, Rui

    2004-01-01

    Portuguese territorial organization has two levels of territorial decision support legitimated: central and local/municipal government (municipalities). The lack an intermediate level of support decision between those levels is a central problem on territorial decision support system. Intermunicipal organization level can it play an important role as an intermediate level of decision-making process. After rejection of the regionalization process in 1998, trough popular referendum, Portuguese ...

  5. The Basic Principle of Calculus?

    Science.gov (United States)

    Hardy, Michael

    2011-01-01

    A simple partial version of the Fundamental Theorem of Calculus can be presented on the first day of the first-year calculus course, and then relied upon repeatedly in assigned problems throughout the course. With that experience behind them, students can use the partial version to understand the full-fledged Fundamental Theorem, with further…

  6. Universal human habitat. Basic principles

    OpenAIRE

    Stepanov Vyacheslav Konstantinovich; Starikov Aleksandr Sergeevich

    2012-01-01

    Standard Rules on the Equalization of Opportunities for Persons with Disabilities were adopted in 1993 by the United Nations. They have been valid since then. The number of disabled and elderly people is ever growing due to injuries, accidents, environmental problems, deterioration of health, population aging and demographic disorders. The term "universal habitat" reads as "universal design" worldwide. The concept of "universal design" was developed by Ronald Mace, American arc...

  7. [The basic principles of leadership].

    Science.gov (United States)

    Pfaff, Holger; Neumann, Melanie; Kuch, Christine; Hammer, Antje; Janssen, Christian; Brinkmann, Anne; Ommen, Oliver

    2009-01-01

    This overview of leadership research provides insights into the different leadership concepts. Early research on leadership focused on personality traits and leadership behaviour as determinants of good leadership. The recognition of leadership as a complex phenomenon resulted in concepts that examined leader characteristics and behaviour in the context of situational conditions. Modern cognitive approaches concentrated on the perception of leaders by followers and the perception of followers by leaders and the cognitive biases involved. There is a tendency in leadership research to integrate the three central aspects of leadership--person, situation and cognition--into a single framework. PMID:19545079

  8. A Research on the Basic Principles and Principle Innovation in Modern, Chinese Economics%现代中国经济学基本原理及学科形态创新研究

    Institute of Scientific and Technical Information of China (English)

    赵复斌

    2012-01-01

    近代至现代时期,国际国内已发生了两个“社会转型”的根本性变化。以此为新的社会背景和历史条件,现代中国经济学基础理论及学科形态开始面临两大课题:一是处于源头上的马克思经济学如何“坚持与创新”的前提问题,二是我们的学科模式怎样“改革与开放”的衔接问题。探索并解决此类基本问题,将会让我们获得某个“杠杆支点”或“开放出口”,这既利于满足现代社会主义的物化实践需要,又利于推动中国经济学走向世界的步伐。本文根据两个“社会转型”的客观实际,推导、论证《资本论》的商品两因素分析将发生重大变化并获得相应进展,由此深化马克思经济学的分析基本点。建筑其上的现代中国经济学及政治经济学的系列概念、原理、规律及学科形态也将发生微妙变化,它们涉及对价值、剩余价值、使用价值、交换价值、质量价值、数量价值等的重新定位,和对资本本原、本质、构成及过程的扩大化认识与论证。%From modern to contemporary eras, two fundamental " social transformations" have taken place in both international and domestic contexts. The basic theories and principle construction modes in modern Chinese economies are accordingly faced up with two fundamental problems, against these new social backgrounds and historical conditions. The first one is the premise that how Marxist economics, as the source theory, carries out "adherence and innovation". The second one is how to make our principle modes in conformity with the " Reform and Opening - up" policy. Explorations and solutions to these fundamental problems offer us a "lever support point" or an "open outlaying". This satisfies the physical practice needs of modern socialism, and pushes Chinese economics forward onto the world stage. Based on the objective situations of the two " social transformations" , this

  9. Biomedical engineering principles

    CERN Document Server

    Ritter, Arthur B; Valdevit, Antonio; Ascione, Alfred N

    2011-01-01

    Introduction: Modeling of Physiological ProcessesCell Physiology and TransportPrinciples and Biomedical Applications of HemodynamicsA Systems Approach to PhysiologyThe Cardiovascular SystemBiomedical Signal ProcessingSignal Acquisition and ProcessingTechniques for Physiological Signal ProcessingExamples of Physiological Signal ProcessingPrinciples of BiomechanicsPractical Applications of BiomechanicsBiomaterialsPrinciples of Biomedical Capstone DesignUnmet Clinical NeedsEntrepreneurship: Reasons why Most Good Designs Never Get to MarketAn Engineering Solution in Search of a Biomedical Problem

  10. Basic principles of knowledge management and its application to the industrial company in tactical operations of maintenance and operational exploitation: A qualitative study

    Directory of Open Access Journals (Sweden)

    Francisco Javier Cárcel Carrasco

    2013-01-01

    Full Text Available Purpose: Although knowledge and its management is, and has been, studied in depth, particularly since the 90’s decade of the past century, especially for the strategic management, innovation, trade, or business administration, there are still many questions on how it articulates or transfers and the barriers to its management, especially when we talk about internal tactical activities that affect staff that we could call "offices", such as maintenance and industrial assembly or exploitation and conduction of the facilities. Because of the peculiarities normally seen in this kind of activity in the industrial companies, the knowledge of these people is strongly based on their experience (strong tacit component, difficult to measure and articulate, and on many occasions, however, this rupture of information-knowledge, can represent a high cost for the company (often assumed to be something inevitable due to the increase in production and service downtime, loss of efficiency, or tuning time of new staff to these areas.Design/methodology/approach: After a description of the State of the art and the basic principles of knowledge management, a qualitative study in an industrial company has been carried out, within the areas of operation and maintenance, in order to know the barriers and facilitators that such involved personnel finds in order to achieve an adequate transmission and use of that knowledge.Findings and Originality/value: Learn about barriers, facilitators and impact that offers the knowledge management in the areas of industrial maintenance, especially among professionals in offices which operate with a high degree of tacit knowledge and with a heavy dependence on the company on these professionals.Research limitations/implications: Those characteristics of a qualitative study in a particular area and within a geographical area, although it can be extrapolated to other types of companies and regional areas.Practical implications: Learn

  11. Perspectives for Developing New Tuberculosis Vaccines Derived from the Pathogenesis of Tuberculosis: I. Basic Principles, II. Preclinical Testing, and III. Clinical Testing

    Directory of Open Access Journals (Sweden)

    Bappaditya Dey

    2013-01-01

    Full Text Available Part I. Basic Principles. TB vaccines cannot prevent establishment of the infection. They can only prevent an early pulmonary tubercle from developing into clinical disease. A more effective new vaccine should optimize both cell-mediated immunity (CMI and delayed-type hypersensitivity (DTH better than any existing vaccine. The rabbit is the only laboratory animal in which all aspects of the human disease can be reproduced: namely, the prevention of most primary tubercles, the arrestment of most primary tubercles, the formation of the tubercle’s solid caseous center, the liquefaction of this center, the formation of cavities and the bronchial spread of the disease. In liquefied caseum, virulent tubercle bacilli can multiply extracellularly, especially in the liquefied caseum next to the inner wall of a cavity where oxygen is plentiful. The bacilli in liquefied caseum cannot be reached by the increased number of activated macrophages produced by TB vaccines. Therefore, new TB vaccines will have little or no effect on the extracellular bacillary growth within liquefied caseum. TB vaccines can only increase the host’s ability to stop the development of new TB lesions that arise from the bronchial spread of tubercle bacilli from the cavity to other parts of the lung. Therefore, effective TB vaccines do not prevent the reactivation of latent TB. Such vaccines only control (or reduce the number of metastatic lesions that result after the primary TB lesion was reactivated by the liquefaction process. (Note: the large number of tubercle bacilli growing extracellularly in liquefied caseum gives rise to mutations that enable antimicrobial resistance—which is a major reason why TB still exists today. Part II. Preclinical Testing. The counting of grossly visible tubercles in the lungs of rabbits after the inhalation of virulent human-type tubercle bacilli is the most pertinent preclinical method to assess the efficacy of new TB vaccines (because an

  12. Phase contrast imaging of the breast. Basic principles and steps towards clinical implementation; Phasenkontrastbildgebung der Brust. Grundlagen und Schritte zur klinischen Implementierbarkeit

    Energy Technology Data Exchange (ETDEWEB)

    Grandl, S.; Sztrokay-Gaul, A.; Auweter, S.D.; Hellerhoff, K. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany)

    2014-03-15

    Breast cancer is the most common cancer and the leading cause of cancer deaths in women worldwide. Mammography is the only imaging technique approved for nationwide breast cancer screening. Digital full field mammography has improved mammographic image quality. Nevertheless, mammography has a low positive predictive value and a low sensitivity especially in mammographically dense breasts. One of the major limitations is the inherently low contrast between healthy breast parenchyma and breast cancer. Phase contrast imaging is based on the phase shift that occurs when X-rays encounter a change in refractive index between different materials. The improved soft tissue contrast makes the technology particularly promising for breast diagnostics. The studies presented here suggest that phase contrast imaging provides additional diagnostic information both using phase contrast mammography and phase contrast computed tomography (CT). This paper provides an overview of the basic principles of the phase contrast imaging and describes recent developments towards in vivo and ex vivo phase contrast imaging of the breast. (orig.) [German] Brustkrebs ist weltweit die haeufigste Tumorerkrankung und die haeufigste Krebstodesursache der Frau. Die Mammographie ist die einzige zugelassene bildgebende Methode zur Brustkrebsfrueherkennung im Rahmen flaechendeckender Screeningprogramme. Trotz Verbesserung der Bildqualitaet und der Befundungsperformance durch die Einfuehrung der digitalen Vollfeldmammographie sind der positiv-praediktive Wert und die Sensitivitaet der Mammographie insbesondere bei mammographisch dichtem Druesenkoerper eingeschraenkt. Dies ist u. a. auf die geringen Dichteunterschiede zwischen gesundem Brustdruesengewebe und intramammaeren Malignomen zurueckzufuehren. Die Phasenkontrastbildgebung macht sich die Phasenverschiebung von Roentgenstrahlen zunutze, die an Materialgrenzen mit unterschiedlichen Brechungsindizes entsteht. Die Technik bietet einen potenziell

  13. Plant physiology

    CERN Document Server

    Duca, Maria

    2015-01-01

    This book covers all aspects of plant physiology: plant cell physiology, water regime of plants, photosynthesis, mineral nutrition, plant respiration, plant growth and development, movements in plants, signal perception and transduction etc. It focuses on the fundamental principles of plant physiology and biochemistry from the molecular level to whole plants, on the mechanisms of plant-environment interactions. The book is intended for students (biologists, physiologists, biochemists, biophysicists, ecologists, geneticists), teachers and researchers. Particular emphasis is given to recent research advances made on national and international levels, as well as to personal experimental results of the author that are relevant for a deeper understanding of processes and for practical implementation of gained knowledge. An essential amount of illustrative material (graphics, images, schemes, illustrations) completes the text and supplies additional information in an accessible manner. At the end of each chapter...

  14. 城市公共空间格局基本原理探析%Analysis on Basic Principles of Urban Public Space Pattern

    Institute of Scientific and Technical Information of China (English)

    徐宁

    2016-01-01

    Urban public space, which is equaly important as urban transport system, is the basic organization and also the dominant element for a city. The research into the pattern of urban public space mainly focuses on the alocation and mechanism of public space, as wel as relfecting the relationship among spatial elements and the relationship between spatial elements and urban context. It is an important fundamental research for grasping the morphological composition of the urban space and its evolution. Based on the theoretical frontiers of urban public space, with a large number of ifeld researches, environmental behavior and morphological quantitative analysis, the paper analyses the general principles of regularities folowed by relatively more successful patterns of urban public space at home and abroad, such as structure adaptation, sites consolidation, hierarchy and continuation, interface constraints etc.%城市公共空间是与城市交通系统同等重要的城市基础性组织及全局性控制要素。城市公共空间格局研究主要关注公共空间的配置及其机理,对把握城市物质空间形态构成及其演进规律是一项重要的基础研究。在长期关注城市公共空间理论前沿的基础上,结合大量田野调查、环境行为实证研究和形态学量化分析,探析了国内外较为成功的城市公共空间格局所遵循的普遍规律性原则,即结构适配、场所固结、层级连续和界面约束原理:好的城市公共空间格局总是与城市结构相适配;有若干独特地点从整个连续系统中凸显出来;形成层级连续系统;并具有明确的限定约束界面。

  15. Role of Logic and Mentality as the Basics of Wittgenstein's Picture Theory of Language and Extracting Educational Principles and Methods According to This Theory

    Science.gov (United States)

    Heshi, Kamal Nosrati; Nasrabadi, Hassanali Bakhtiyar

    2016-01-01

    The present paper attempts to recognize principles and methods of education based on Wittgenstein's picture theory of language. This qualitative research utilized inferential analytical approach to review the related literature and extracted a set of principles and methods from his theory on picture language. Findings revealed that Wittgenstein…

  16. Principles of project management

    Science.gov (United States)

    1982-01-01

    The basic principles of project management as practiced by NASA management personnel are presented. These principles are given as ground rules and guidelines to be used in the performance of research, development, construction or operational assignments.

  17. Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89.

    Science.gov (United States)

    2002-01-01

    This report presents detailed information on age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. These reference values provide needed input to prospective dosimetry calculations for radiation protection purposes for both workers and members of the general public. The purpose of this report is to consolidate and unify in one publication, important new information on reference anatomical and physiological values that has become available since Publication 23 was published by the ICRP in 1975. There are two aspects of this work. The first is to revise and extend the information in Publication 23 as appropriate. The second is to provide additional information on individual variation among grossly normal individuals resulting from differences in age, gender, race, or other factors. This publication collects, unifies, and expands the updated ICRP reference values for the purpose of providing a comprehensive and consistent set of age- and gender-specific reference values for anatomical and physiological features of the human body pertinent to radiation dosimetry. The reference values given in this report are based on: (a) anatomical and physiological information not published before by the ICRP; (b) recent ICRP publications containing reference value information; and (c) information in Publication 23 that is still considered valid and appropriate for radiation protection purposes. Moving from the past emphasis on 'Reference Man', the new report presents a series of reference values for both male and female subjects of six different ages: newborn, 1 year, 5 years, 10 years, 15 years, and adult. In selecting reference values, the Commission has used data on Western Europeans and North Americans because these populations have been well studied with respect to antomy, body composition, and physiology. When appropriate, comparisons are made between the chosen reference values and data from several Asian populations

  18. 农作物总DNA提取的基本原理和主要方法概述%Basic Principle and Main Method of Crop Total DNA Extraction

    Institute of Scientific and Technical Information of China (English)

    徐亮

    2011-01-01

    概述了农作物DNA提取的基本原理,总结了DNA提取各步骤的操作经验,并介绍了几种常用的DNA提取方法.%The paper summarizes the basic principle of crop DNA extraction and the operation experience of each DNA extraction step,and introduces several commonly used DNA extraction method.

  19. Integrating the Carbon and Water Footprints’ Costs in the Water Framework Directive 2000/60/EC Full Water Cost Recovery Concept: Basic Principles Towards Their Reliable Calculation and Socially Just Allocation

    OpenAIRE

    Anastasia Papadopoulou; Stavroula Tsitsifli; Vasilis Kanakoudis

    2012-01-01

    This paper presents the basic principles for the integration of the water and carbon footprints cost into the resource and environmental costs respectively, taking the suggestions set by the Water Framework Directive (WFD) 2000/60/EC one step forward. WFD states that full water cost recovery (FWCR) should be based on the estimation of the three sub-costs related: direct; environmental; and resource cost. It also strongly suggests the EU Member States develop and apply effective water pricing ...

  20. Basic electronics

    CERN Document Server

    Tayal, DC

    2010-01-01

    The second edition of this book incorporates the comments and suggestions of my friends and students who have critically studied the first edition. In this edition the changes and additions have been made and subject matter has been rearranged at some places. The purpose of this text is to provide a comprehensive and up-to-date study of the principles of operation of solid state devices, their basic circuits and application of these circuits to various electronic systems, so that it can serve as a standard text not only for universities and colleges but also for technical institutes. This book

  1. The Basic Principles and Methods of Lightning Protection Design of Gas Pipeline%燃气管道防雷设计的基本原则和方法

    Institute of Scientific and Technical Information of China (English)

    叶平; 隋晓峰; 吴经尊; 林世祺; 熊芳瑜

    2012-01-01

    本文首先分析了燃气管道可能遭受雷击的主要通道,然后提出了堵塞这些主要危害通道的基本思路和基本技术要求,并对燃气管道防雷设计的基本原则和方法作了详尽的论述,为燃气管道的防雷设计提供了实践依据.%This paper analyzes the main channel may be struck by lightning of gas pipeline, and then proposes the basic ideas and basic technical requirements to plug these major hazards channel, and makes a detailed exposition of the basic principles and methods of lightning protection design of the gas pipeline, providing a practical basis.

  2. Assessment of In Vivo Clinical Product Performance of a Weak Basic Drug by Integration of In Vitro Dissolution Tests and Physiologically Based Absorption Modeling.

    Science.gov (United States)

    Ding, Xuan; Gueorguieva, Ivelina; Wesley, James A; Burns, Lee J; Coutant, Carrie A

    2015-11-01

    Effective integration of in vitro tests and absorption modeling can greatly improve our capability in understanding, comparing, and predicting in vivo performances of clinical drug products. In this case, we used a proprietary drug candidate galunisertib to describe the procedures of designing key in vitro tests, analyzing relevant experimental and trial data, and integrating them into physiologically based absorption models to evaluate the performances of its clinical products. By simulating the preclinical study result, we estimated high in vivo permeability for the drug. Given the high sensitivity of its solubility to pH, supersaturation may play an important role in the absorption of galunisertib. Using the dynamic dissolution test, i.e., artificial stomach-duodenum (ASD) model and simulation, we concluded galunisertib in solution or tablet products could maintain supersaturation during the transit in the gastrointestinal tract (GIT). A physiologically based absorption model was established by incorporating these key inputs in the simulation of Trial 1 results of galunisertib solution. To predict the performance of three tablet products, we developed z-factor dissolution models from the multi-pH USP dissolution results and integrate them into the absorption model. The resultant biopharmaceutical models provided good prediction of the extent of absorption of all three products, but underestimated the rate of absorption of one tablet product. Leveraging the ASD result and optimization with the dissolution model, we identified the limitation of the model due to complexity of estimating the dissolution parameter z and its in vitro-in vivo correlation. PMID:26126932

  3. Basic principles of the cardiopulmonary resuscitation——remain essentially the same despite all apparent changes%论心肺复苏的核心原理——万变不离其宗

    Institute of Scientific and Technical Information of China (English)

    孟庆义

    2011-01-01

    This paper expounds the basic principles of the cardiopulmonary resuscitation. The main points include the Venturi - effect in the mouth - to - mouth ventilation, the key points of chest compression analyzed with the Newton's laws of mechanics and law of energy conservation, and the development of electrical defibrillator with the Joule - Lenz law in the physics and principle of negation of negation in the philosophy. To master the basic principles of the cardiopulmonary resuscitation was the basis for studying and expanding the technique competence of cardiopulmonary resuscitation.%本文对心肺复苏(CPR)的一些核心原理进行了论述,主要内容有口对口人工呼吸与文丘里效应,用牛顿力学三大定律和能量守恒定律等原理解析胸部按压的操作要点,物理学的焦耳-楞次定律和哲学的否定之否定规律与体外电除颤技术的发展等;还提出掌握CPR的核心原理是发展和学习CPR技术的基础.

  4. A basic study on molecular hydrogen (H2 inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level

    Directory of Open Access Journals (Sweden)

    Ono Hirohisa

    2012-08-01

    Full Text Available Abstract Background In animal experiments, use of molecular hydrogen ( H2 has been regarded as quite safe and effective, showing benefits in multiple pathological conditions such as ischemia-reperfusion injury of the brain, heart, kidney and transplanted tissues, traumatic and surgical injury of the brain and spinal cord, inflammation of intestine and lung , degenerative striatonigral tissue and also in many other situations. However, since cerebral ischemia patients are in old age group, the safety information needs to be confirmed. For the feasibility of H2 treatment in these patients, delivery of H2 by inhalation method needs to be checked for consistency. Methods Hydrogen concentration (HC in the arterial and venous blood was measured by gas chromatography on 3 patients, before, during and after 4% (case 1 and 3% (case2,3 H2 gas inhalation with simultaneous monitoring of physiological parameters. For a consistency study, HC in the venous blood of 10 patients were obtained on multiple occasions at the end of 30-min H2 inhalation treatment. Results The HC gradually reached a plateau level in 20 min after H2 inhalation in the blood, which was equivalent to the level reported by animal experiments. The HC rapidly decreased to 10% of the plateau level in about 6 min and 18 min in arterial and venous blood, respectively after H2 inhalation was discontinued. Physiological parameters on these 3 patients were essentially unchanged by use of hydrogen. The consistency study of 10 patients showed the HC at the end of 30-min inhalation treatment was quite variable but the inconsistency improved with more attention and encouragement. Conclusion H2 inhalation of at least 3% concentration for 30 min delivered enough HC, equivalent to the animal experiment levels, in the blood without compromising the safety. However, the consistency of H2 delivery by inhalation needs to be improved.

  5. Ukrainian state service of the united time and standard frequencies: structure and basic principles for providing the country with high-precision time and frequency information.

    Science.gov (United States)

    Velichko, O. M.; Safronov, Yu. I.; Klejman, O. S.; Solovjov, V. S.; Tkachuk, A. A.; Yatskiv, Ya. S.

    The organization structure and main problems of the Ukrainian state service of the united time and standard frequencies are considered. Its present state and the role of its basic divisions in providing various fields of the Ukrainian economics, including the space science and its applications, with the time and frequency information are presented.

  6. The Principle of Administrative Emergency Basic Philosophy Consideration%行政应急性原则的基础理念

    Institute of Scientific and Technical Information of China (English)

    刘莘

    2012-01-01

    Based on the principle of administrative emergency research and conceptual controversy carding, this article defines the administration emergency principle value orientation is to protect the order, embody the administrative power of concentration and expansion of public attention, priority, benefit, efficiency and fairness. It summed up the ultimate goal of the principle administrative emergency, namely the administration emergency principle and ultimately to translate into how rational allocation of administrative power and protect rights of relative person. For balance between public interests and individual interests, public order and freedom of citizens, proper institutional arrangement will be done. Finally, in emergency situations, public power should have an internal balance.%本文通过对行政应急性原则的研究现状及概念争议的梳理,界定行政应急性原则的价值取向为秩序保护,体现为行政权的集中与扩张,公益优先、兼顾私益,效率优先兼顾公平三个方面,进而总结行政应急原则的终极目标,即行政应急性原则最终还是要转化为如何合理配置行政权与保护相对人权利这一经典问题。在兼顾公共利益和个人利益,兼顾公共秩序与公民自由的基础上,进行恰当的制度安排。最后,在应急状态下,公权力要有一种内部的平衡。

  7. 公平互利原则:国际经济法基本原则选择--兼与平等互利原则比较%Fairness and Mutual Benefit:The Basic Principle of International Economic Law:A Comparative Study with the Principle of Equality and Mutual Benefit

    Institute of Scientific and Technical Information of China (English)

    强蔷

    2014-01-01

    The basic principles of the international economic law find expression in each of its specifications and practices. The principle of fairness and mutual benefit, as one of the basic principles of international economic law reflects the basic value orientation of the theory of international economic law and can provide a correct driec-tion for international economic activities. However, the principle of fairness and mutual benefit has been under controversy among international economic law circles, and some scholars think that the principle of equality and mutual benefit should be applied. The former emphasizes fairness while the latter emphasizes equality. In the in-ternational economic activities, the principle of fairness and mutual benefit is more applicable than the value of e-quality and mutual benefit so that the former is more suitable as a basic principle of international economic law.%国际经济法的每一项制度或具体实践都能体现其基本原则,其中公平互利原则作为国际经济法的基本原则之一主要体现了国际经济法理论的基本价值取向,并在国际经济活动中能够提供正确的方向指导。然而学界对于公平互利原则一直存在争议,部分学者认为国际经济法应该适用平等互利原则,前者强调公平,后者强调平等。在具体国际经济交往活动中,公平互利比平等互利更具有普适价值,公平互利原则作为国际经济法的基本原则更合适。

  8. 理论联系实际:马克思主义理论课教学的基本原则%Integrating Theory with Real Situations:the Basic Principle in Marxist Theory Teaching

    Institute of Scientific and Technical Information of China (English)

    王雪凌

    2011-01-01

    理论联系实际是马克思主义理论课教学的基本原则。坚持这一原则是加强和改进马克思主义理论课教学,增强教学实效性的必然要求。正确掌握马克思主义理论是理论联系实际的首要条件,全面把握社会实际和学生特点是理论联系实际的必要条件。深入贯彻这一原则应立足于教学目的的实现,选取典型性的材料,运用社会实践等多种教学方式和坚持实事求是的态度,把理论和实际有机结合。%Integrating theory with real situations is the basic principle in Marxist theory teaching.It is compulsory to adhere to this principle in order to improve the teaching of Marxist theory.The precondition of implementing this principle is to well command Marxist theory;and the necessary condition is to well understand the social realities and the students.The application of the teaching principle should be oriented towards the achievement of teaching goals.

  9. Basic physics for all

    CERN Document Server

    Kumar, B N

    2012-01-01

    This is a simple, concise book for both student and non-physics students, presenting basic facts in straightforward form and conveying fundamental principles and theories of physics. This book will be helpful as a supplement to class teaching and to aid those who have difficulty in mastering concepts and principles.

  10. A Review on the Basic Principles Involved in Animal Training%动物行为训练的理论基础

    Institute of Scientific and Technical Information of China (English)

    刘赫

    2014-01-01

    本文阐述了动物行为训练的生物学背景和相应的心理学和神经生理学原理,论述了动物四种学习方式以及动物训练的两种方法:强化和惩罚。%A wide range of background and relative principles of psychology and neurophysiology are reviewed for animal training. This paper discussed four different styles on animal learning. Two methods of animal training are presented by reinforcement and punishment.

  11. The Central Endocrine Glands: Intertwining Physiology and Pharmacy

    OpenAIRE

    Emerson, Mitchell R.

    2007-01-01

    The initial courses in didactic pharmacy curriculum are designed to provide core scientific knowledge and develop learning skills that are the basis for highly competent application and practice of pharmacy. Commonly, students interpret this scientific base as ancillary to the practice of pharmacy. Physiology courses present a natural opportunity for the instructor to introduce basic pharmaceutical principles that form the foundation of pharmacological application early in the professional cu...

  12. Basic digital signal processing

    CERN Document Server

    Lockhart, Gordon B

    1985-01-01

    Basic Digital Signal Processing describes the principles of digital signal processing and experiments with BASIC programs involving the fast Fourier theorem (FFT). The book reviews the fundamentals of the BASIC program, continuous and discrete time signals including analog signals, Fourier analysis, discrete Fourier transform, signal energy, power. The text also explains digital signal processing involving digital filters, linear time-variant systems, discrete time unit impulse, discrete-time convolution, and the alternative structure for second order infinite impulse response (IIR) sections.

  13. Powerful flaring configurations in solar active regions: magnetic topology via special features of delta-structure phenomenon. I. Basic principles of topological model

    CERN Document Server

    Ikhsanov, R N; Marushin, Yu.V.

    2003-01-01

    The close connection of magnetic field structure on the one hand and observable features of complex ARs with high flare efficiency on the other one is investigated in frames of so-called dynamic classification of flaring magnetic configurations (FMC) and the simple topological model of interacting magnetic complexes (IMC) suggested by Ikhsanov (1982). The primary objective of the present work is to expose general statements of the specified model and classification, the secondary one assumes the critical analysis and logical generalization of several important regularities being frequently observable in evolution stages of a typical complex AR with powerful flares including proton ones. Those cases are basically examined where the development of photospheric situation was marked by the formation of delta-configuration phenomenon described by Kunzel (1960) as one of the most impressive precursors of high flare activity. Without trying to use any additional assumptions and alternative hypotheses, the qualitativ...

  14. SUMMARY OF BASIC PRINCIPLES OF ACOUSTIC THEORY = POLUIÇÃO SONORA: SÍNTESE DE PRINCÍPIOS FUNDAMENTAIS DA TEORIA ACÚSTICA

    Directory of Open Access Journals (Sweden)

    Adriano Bressane

    2010-01-01

    Full Text Available Several studies are reported on noise pollution literature, with many different approaches. However, there are evident in such publications fundamentals of acoustic theory, aiming at a more appropriate characterization of sound phenomenon. This paper aims to provide an alternative source of consultation for those faced with the fragmented and too much information, sometimes an obstacle to understanding main physical aspects of noise pollution. This paper to present and discuss concepts concerning the sound properties, principles of sound propagation and related phenomena. = Inúmeros são os trabalhos reportados na literatura sobre poluição sonora, com as mais diversas ênfases e enfoques. Todavia, tais publicações não evidenciam os fundamentos da teoria acústica, visando uma caracterização mais apropriada do fenômeno sonoro. O presente trabalho tem por finalidade proporcionar uma fonte alternativa de consulta para aqueles que deparam com a fragmentada e demasiada quantidade de informações, por vezes obstáculo para compreensão física dos principais aspetos da poluição sonora. Aqui são discutidos e apresentados os principais conceitos relacionados às propriedades do som, princípios de propagação e fenômenos sonoros correlatos.

  15. Artificial Nutrition: Principles and Practice of Enteral Feeding

    OpenAIRE

    Lloyd, David A. J.; Powell-Tuck, Jeremy

    2004-01-01

    Enteral feeding is a commonly used form of nutritional supplementation for patients with intestinal failure, both in hospitals and in the community. This article concentrates on the basic principles of enteral feeding, including the physiological effects of feeding into the intestinal tract. It covers the indications for enteral feeding, the different methods of supplying enteral feeds to the gastrointestinal tract, and the potential complications. There is also a discussion of the indication...

  16. Basic principles of a systematic arrangement of regulatory subjects, instruments and levels under the atomic energy law and the radiation protection law

    International Nuclear Information System (INIS)

    Considering a re-arrangement of regulatory subjects and instruments, there are two aspects to be taken into account: a vertical distribution on the one hand, which has to differentiate between legal provisions having the force of law, and those being given in non-statutory regulations. A horizontal distribution on the other hand has to determine whether and how the regulatory subject matters are to be covered by several acts, ordinances or regulations, and assigned to subject-related chapters, sections, etc., of these provisions. A comprehensive, systematic arrangement covering the contents of the atomic energy law and the radiation protection law is suggested to be done along the following lines of orientation: I. Purpose, scope of application, terms and definitions. II. Handling of radioactive materials and application of ionizing radiation. (1) General requirements. (2) Licensing. (3) Transport, imports and exports. (4) Storage and disposal. (5) Common, basic provisions. III. Preventive radiation protection in general terms. IV. Third party liability and financial security. V. Common provisions - Federal Radiation Protection Office - Punishable acts and statutory offences. (orig./HSCH)

  17. Beware of agents when flying aircraft: Basic principles behind a generic methodology for the evaluation and certification of advanced aviation systems

    Science.gov (United States)

    Javaux, Denis; Masson, Michel; Dekeyser, Veronique

    1994-01-01

    There is currently a growing interest in the aeronautical community to assess the effects of the increasing levels of automation on pilots' performance and overall safety. The first effect of automation is the change in the nature of the pilot's role on the flight deck. Pilots have become supervisors who monitor aircraft systems in usual situations and intervene only when unanticipated events occur. Instead of 'hand flying' the airplane, pilots contribute to the control of aircraft by acting as mediators, instructions given to the automation. By eliminating the need for manually controlling normal situations, such a role division has reduced the opportunities for the pilot to acquire experience and skills necessary to safely cope with abnormal events. Difficulties in assessing the state and behavior of automation arise mainly from four factors: (1) the complexity of current systems and consequence mode-related problems; (2) the intrinsic autonomy of automation which is able to fire mode transitions without explicit commands from the pilots; (3) the bad quality of feed-back from the control systems displays and interfaces to the pilots; and (4) the fact that the automation currently has no explicit representation of the current pilots' intentions and strategy. Assuming certification has among its major goals to guarantee the passengers' and pilots' safety and the airplane integrity under normal and abnormal operational conditions, the authors suggest it would be particularly fruitful to come up with a conceptual reference system providing the certification authorities both with a theoretical framework and a list of principles usable for assessing the quality of the equipment and designs under examination. This is precisely the scope of this paper. However, the authors recognize that the conceptual presented is still under development and would thus be best considered as a source of reflection for the design, evaluation and certification processes of advanced

  18. Técnicas básicas de electroencefalografía: principios y aplicaciones clínicas Basic techniques of electroencephalography: principles and clinical applications

    Directory of Open Access Journals (Sweden)

    F. Ramos-Argüelles

    2009-01-01

    Full Text Available El electroencefalograma es una técnica de exploración funcional del sistema nervioso central (SNC, de relativa antigüedad, pero que aún hoy día sigue siendo una herramienta de gran ayuda para el clínico en el diagnóstico y seguimiento de algunas patologías, como pueden ser la epilepsia, las encefalopatías, alteraciones del estado de conciencia, infecciones del SNC, etc. Es, por otro lado, una herramienta diagnóstica con aplicaciones que están en plena expansión, en combinación con otras técnicas neurofisiológicas, como es en el campo del estudio y diagnóstico de la patología de sueño (polisomnografía, test de latencias múltiples del sueño... y la monitorización intraoperatoria junto con los potenciales evocados somatosensoriales. Se describen en este trabajo cuáles son los fundamentos técnicos de la electroencefalografía, haciendo especial hincapié en sus principales aplicaciones clínicas y en las perspectivas del futuro.The electroencephalogram is a technique for the functional exploration of the central nervous system (CNS. It is a relatively old technique but even today it continues to be a tool of great assistance to the clinician in diagnosing and treating certain pathologies, such as epilepsy, encephalopathies, alterations to the state of consciousness, CNS infections, etc. On the other hand, it is a diagnostic tool whose applications are expanding in combination with other neurophysiological techniques, such as in the field of the study and diagnosis of sleep pathology (polysomnography, multiple sleep latency test... and in intraoperative monitoring together with somasensory evoked potentials. This article describes the basic techniques of electroencephalography, with special emphasis on its main clinical applications and on future perspectives

  19. Anatomy & Physiology

    Science.gov (United States)

    ... Surveillance Modules » Anatomy & Physiology Cancer Registration & Surveillance Modules Anatomy & Physiology Intro to the Human Body Body Functions & Life Process Anatomical Terminology Review ...

  20. Risk communication basics

    Energy Technology Data Exchange (ETDEWEB)

    Corrado, P.G. [Lawrence Livermore National Laboratory, CA (United States)

    1995-12-31

    In low-trust, high-concern situations, 50% of your credibility comes from perceived empathy and caring, demonstrated in the first 30 s you come in contact with someone. There is no second chance for a first impression. These and other principles contained in this paper provide you with a basic level of understanding of risk communication. The principles identified are time-tested caveats and will assist you in effectively communicating technical information.

  1. Risk communication basics

    International Nuclear Information System (INIS)

    In low-trust, high-concern situations, 50% of your credibility comes from perceived empathy and caring, demonstrated in the first 30 s you come in contact with someone. There is no second chance for a first impression. These and other principles contained in this paper provide you with a basic level of understanding of risk communication. The principles identified are time-tested caveats and will assist you in effectively communicating technical information

  2. 重申马克思主义基本原理的方法论价值--以2013版《马克思主义基本原理概论》教材修订为例%Restating the Methodology Value of the Basic Principles of Marxism---From the Perspective of Textbook Revision of The Basic Principles of Marxism Published in 2013

    Institute of Scientific and Technical Information of China (English)

    王凡

    2014-01-01

    Marxist philosophy is both a scientific world outlook and also scientific methodology. Methodology is one of the fundamental problems in the field of basic principles of Marxism. During the researches and teaching works of Marxist theory, the value of Marxist methodology should be paid more at-tention to for it could be provided as powerful thinking tools and methods for academic researches in the development of socialism with Chinese characteristics. It is the obligatory responsibility and mission of Marxist theoretical workers to strengthen researches of Marxism methodology, and construct the new form of Marxism methodology, and reaffirm the methodological value of Marxist basic principles.%马克思主义哲学既是科学的世界观也是科学的方法论。方法论问题是马克思主义基本原理中的根本性问题之一。在马克思主义理论研究和教学工作中,应重视马克思主义方法论的价值,使其能够为中国特色社会主义事业的发展提供强大的思维工具和方法。加强对马克思主义方法论的研究,构筑马克思主义方法论的新形态,重申马克思主义基本原理的方法论价值,是马克思主义理论工作者义不容辞的责任和使命。

  3. 重申马克思主义基本原理的方法论价值--以2013版《马克思主义基本原理概论》教材修订为例%Restating the Methodology Value of the Basic Principles of Marxism---From the Perspective of Textbook Revision of The Basic Principles of Marxism Published in 2013

    Institute of Scientific and Technical Information of China (English)

    王凡

    2014-01-01

    马克思主义哲学既是科学的世界观也是科学的方法论。方法论问题是马克思主义基本原理中的根本性问题之一。在马克思主义理论研究和教学工作中,应重视马克思主义方法论的价值,使其能够为中国特色社会主义事业的发展提供强大的思维工具和方法。加强对马克思主义方法论的研究,构筑马克思主义方法论的新形态,重申马克思主义基本原理的方法论价值,是马克思主义理论工作者义不容辞的责任和使命。%Marxist philosophy is both a scientific world outlook and also scientific methodology. Methodology is one of the fundamental problems in the field of basic principles of Marxism. During the researches and teaching works of Marxist theory, the value of Marxist methodology should be paid more at-tention to for it could be provided as powerful thinking tools and methods for academic researches in the development of socialism with Chinese characteristics. It is the obligatory responsibility and mission of Marxist theoretical workers to strengthen researches of Marxism methodology, and construct the new form of Marxism methodology, and reaffirm the methodological value of Marxist basic principles.

  4. Basics of Quantum Computation

    OpenAIRE

    Vedral, Vlatko; Martin B. Plenio

    1998-01-01

    Quantum computers require quantum logic, something fundamentally different to classical Boolean logic. This difference leads to a greater efficiency of quantum computation over its classical counter-part. In this review we explain the basic principles of quantum computation, including the construction of basic gates, and networks. We illustrate the power of quantum algorithms using the simple problem of Deutsch, and explain, again in very simple terms, the well known algorithm of Shor for fac...

  5. Dynamical principles in neuroscience

    International Nuclear Information System (INIS)

    Dynamical modeling of neural systems and brain functions has a history of success over the last half century. This includes, for example, the explanation and prediction of some features of neural rhythmic behaviors. Many interesting dynamical models of learning and memory based on physiological experiments have been suggested over the last two decades. Dynamical models even of consciousness now exist. Usually these models and results are based on traditional approaches and paradigms of nonlinear dynamics including dynamical chaos. Neural systems are, however, an unusual subject for nonlinear dynamics for several reasons: (i) Even the simplest neural network, with only a few neurons and synaptic connections, has an enormous number of variables and control parameters. These make neural systems adaptive and flexible, and are critical to their biological function. (ii) In contrast to traditional physical systems described by well-known basic principles, first principles governing the dynamics of neural systems are unknown. (iii) Many different neural systems exhibit similar dynamics despite having different architectures and different levels of complexity. (iv) The network architecture and connection strengths are usually not known in detail and therefore the dynamical analysis must, in some sense, be probabilistic. (v) Since nervous systems are able to organize behavior based on sensory inputs, the dynamical modeling of these systems has to explain the transformation of temporal information into combinatorial or combinatorial-temporal codes, and vice versa, for memory and recognition. In this review these problems are discussed in the context of addressing the stimulating questions: What can neuroscience learn from nonlinear dynamics, and what can nonlinear dynamics learn from neuroscience?

  6. Quantum electronics basic theory

    CERN Document Server

    Fain, V M; Sanders, J H

    1969-01-01

    Quantum Electronics, Volume 1: Basic Theory is a condensed and generalized description of the many research and rapid progress done on the subject. It is translated from the Russian language. The volume describes the basic theory of quantum electronics, and shows how the concepts and equations followed in quantum electronics arise from the basic principles of theoretical physics. The book then briefly discusses the interaction of an electromagnetic field with matter. The text also covers the quantum theory of relaxation process when a quantum system approaches an equilibrium state, and explai

  7. Solid state spectroscopies basic principles and applications

    CERN Document Server

    Gonzalo, Julio A; De Frutos, Jose

    2002-01-01

    Materials physics is a very active research field at present and it is expected to remain so in the foreseeable future. Different spectroscopies are currently used to investigate the structure and dynamics of crystalline materials. Some traditional spectroscopies are presented in this book: optical, magnetic resonance, ultrasonic, brillouin, neutron scattering, soft mode and dielectric response spectroscopies. For all of them, the presentation is complemented with some reference material for more modern or sophisticated spectroscopies.This book should be useful as an introductory textbook for

  8. Environmental background assessment: basic principles and practice

    International Nuclear Information System (INIS)

    Background assessment is crucial in setting remediation and management goals, in identifying contamination trends and in providing screening tools for the selection of contaminants of concern. Legal requirements and guideline documents place great emphasis onto the establishment of background levels. This contribution discusses background estimates for metals and organics in relation to bioavailability and to its potential impact onto living systems. Methods for defining background in Environmental Risk Assessment are provided by the US EPA and by the Dutch Added Risk Approach. Cited case studies, taken from projects carried out in Italy and abroad, show that practical approaches vary significantly. A standardised database of soil, sediment and water background levels for different contaminants, as well as a more comprehensive guideline of background assessment, are urgently needed

  9. Basic principles of ultrafast Raman loss spectroscopy

    Indian Academy of Sciences (India)

    N K Rai; A Y Lakshmanna; V V Namboodiri; S Umapathy

    2012-01-01

    When a light beam passes through any medium, the effects of interaction of light with the material depend on the field intensity. At low light intensities the response of materials remain linear to the amplitude of the applied electromagnetic field. But for sufficiently high intensities, the optical properties of materials are no longer linear to the amplitude of applied electromagnetic field. In such cases, the interaction of light waves with matter can result in the generation of new frequencies due to nonlinear processes such as higher harmonic generation and mixing of incident fields. One such nonlinear process, namely, the third order nonlinear spectroscopy has become a popular tool to study molecular structure. Thus, the spectroscopy based on the third order optical nonlinearity called stimulated Raman spectroscopy (SRS) is a tool to extract the structural and dynamical information about a molecular system. Ultrafast Raman loss spectroscopy (URLS) is analogous to SRS but is more sensitive than SRS. In this paper, we present the theoretical basis of SRS (URLS) techniques which have been developed in our laboratory.

  10. MIGRAINE: BASIC PRINCIPLES OF TREATMENT AND PREVENTION

    Directory of Open Access Journals (Sweden)

    O. R. Esin

    2014-07-01

    Full Text Available Modern recommendations for the migraine attack treatment and it's prophylaxis are analyzed in this review. Established, that acetylsalicylic acid, diclofenac potassium, ibuprofen, naproxen, paracetamol, metamizol and their combination with caffeine are drugs of the first choice for migraine attack treatment. Metoclopramide and domperidone are used to reduce nausea and vomiting. Also triptans are high effective drugs for migraine attack treatment. Metoprolol, propranolol, flunarizine, valproic acid can be used for migraine prophylaxis. Drugs of the second choice are: amitriptyline, venlafaxine, naproxen and bisoprolol.

  11. Bilingualism: Beyond Basic Principles. Multilingual Matters.

    Science.gov (United States)

    Dewaele, Jean-Marc, Ed.; Housen, Alex, Ed.; Wei, Li, Ed.

    This collection of papers focuses on individual bilingualism and societal and educational phenomena. After "Introduction and Overview" (Jean-Marc Dewaele, Alex Housen, and Li Wei), 12 papers include: (1) "Who is Afraid of Bilingualism?" (Hugo Baetens Beardsmore); (2) "The Importance of being Bilingual" (John Edwards); (3) "Towards a More…

  12. Matriz informatizada de principios básicos de seguridad: una alternativa útil para su aprendizaje y aplicación // Computerized matrix of safety basic principles: a useful alternative for their learning and application

    Directory of Open Access Journals (Sweden)

    Antonio Torres-Valle

    2011-08-01

    Full Text Available ResumenEl artículo presenta un resumen general de las características distintivas de varios métodos deanálisis de seguridad. Partiendo de las limitaciones intrínsecas de los mismos para realizarevaluaciones integrales de los principios de seguridad, se propone un método de fácil manejo pararealizar análisis cualitativos de seguridad, dirigido además a sistematizar el uso de los PrincipiosBásicos de Seguridad (PBS. Esta alternativa tiene como objetivo primordial promover el aprendizajede los PBS. Las bases metodológicas del método propuesto son, una matriz interdependiente dePBS y un sistema de seguimiento de configuraciones peligrosas que enlaza los sistemastecnológicos de la instalación y/o las características gerenciales de la entidad estudiada, con los PBScorrespondientes. El artículo muestra el uso del código utilizando como referencia una instalaciónsimplificada.Palabras claves: seguridad, principios, métodos, evaluación, configuración, control.___________________________________________________________________________AbstractThe paper presents an abstract of the distinctive characteristics of various methods of safety analysis.Beginning from the inherent limitations of these methods for the integral assessments of the safetyprinciples, is proposed an easy-to-manage method for qualitative safety analysis, which as additionalcapability can be used to interpret and apply the Basic Safety Principles (BSP. The principalobjective of this alternative is the BSP learning promotion. The methodological bases of the proposedmethod are the interdependent matrix of BSP and the system to trace dangerous configurations thatcoupled the technological systems of the facility and/or the management characteristics of the studiedentity with the respective BSP. The paper shows the use of the computer code using as reference asimplified facility.Key words: safety, principles, methods, assessment, configuration, control

  13. 团队项目教学法在全科医学概论教学中的应用与探讨%Application of Team Project Teaching Method in the Teaching of Basic Principles of General Practice

    Institute of Scientific and Technical Information of China (English)

    朱舜; 张昊; 汪小玉

    2012-01-01

    To investigate the application of team project teaching method in the teaching of the basic principles of general practice. Methods A questionnaire - based survey was performed in 98 medical students majoring in clinical medicine who had experienced the team project teaching method in the learning of basic principles of general practice. Results Of the 98 students, 80 ( 81. 6% ) took an active part in the project, 63 ( 64. 3% ) were equal to team roles, 90 ( 91. 8% ) could take the initiative to communicate with others, 59 ( 60. 2% ) thought the team leader did well in project planning and team management, 81 ( 82. 1% ) believed that the project could satisfy the teaching goals, 89 ( 90. 8% ) believed the teacher had provided necessary guidance. Conclusion Team project teaching method improves medical students'career aspiration to becoming a general practitioner and their professional quality, and promotes teachers' professional competence and standard of teaching%目的 了解团队项目教学法在全科医学概论教学中对医学生全科医疗职业能力培养的影响.方法 对2010级、2011级临床医学专业2个班共98名学生进行全科医学概论团队项目教学的尝试,并采用问卷进行调查.结果 有81.6%(80/98)的学生积极参与团队项目教学;64.3%(63/98)的学生认为自己能够胜任团队角色,91.8%(90/98)的学生能主动相互交流,60.2%(59/98)的学生认为团队长在项目策划与团队管理方面做得较好;82.7%(81/98)的学生认为项目内容符合教学需要;90.8%(89/98)的学生认为教师起到了指导作用.结论 团队项目教学法有助于医学生全科医生职业志向及职业素质的培养,有助于提高教师的专业能力与教学水平.

  14. 我国行政法基本原则的反思与重述——基于宪法及行政法律规范文本的分析%Reflection and Restatement on the Basic Principles in Chinese Administrative Law——Based on the Analysis on the Text of Constitution and Administrative Regulations

    Institute of Scientific and Technical Information of China (English)

    代温世

    2012-01-01

    Most scholars on administrative law determine the basic principles of Chinese administrative law based on the criteria,but there are several problems in this study such as the uncertainness of the criteria.Foreign experience has shown that the establishment of basic principles in administrative law should be based on regulated foundation.Only administration by law can be defined basic principle to build basic principles in Chinese administrative law from the texts researching Chinese constitution and administrative regulations.The principle of law priority,the principle of law reservation and the principle of administrative procedures by law are interpreted from the principle of administrative by law.%行政法学者多是依据标准来确定我国行政法基本原则,但该研究进路存在着标准的不确定性等问题。域外经验表明,行政法基本原则的确立应具有规范依据。考察我国宪法及行政法律规范,从文本出发来构建我国行政法基本原则,能够称其为基本原则的只有依法行政原则。从依法行政原则中能够演绎出法律优位原则、法律保留原则和行政程序法定原则。

  15. Physiology for engineers applying engineering methods to physiological systems

    CERN Document Server

    Chappell, Michael

    2016-01-01

    This book provides an introduction to qualitative and quantitative aspects of human physiology. It looks at biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, including electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text there are introductions to measuring and quantifying physiological processes using both signal and imaging technologies. Physiology for Engineers describes the basic structure and models of cellular systems, the structure and function of the cardiovascular system, the electrical and mechanical activity of the heart and provides an overview of the structure and function of the respiratory and nervous systems. It also includes an introduction to the basic concepts and applications of reacti...

  16. Brain Basics

    Medline Plus

    Full Text Available ... Neurons & Neural Circuits Neurons are the basic working unit of the brain and nervous system. These cells ... A nerve cell that is the basic, working unit of the brain and nervous system, which processes ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are the basic working unit of the brain ... specialized for the function of conducting messages. A neuron has three basic parts: Cell body which includes ...

  18. Brain Basics

    Medline Plus

    Full Text Available ... Basics will introduce you to some of this science, such as: How the brain develops How genes and the environment affect the brain The basic structure of the brain How different parts of ...

  19. Backpack Basics

    Science.gov (United States)

    ... How Can I Help a Friend Who Cuts? Backpack Basics KidsHealth > For Teens > Backpack Basics Print A ... it can cause back problems or even injury. Backpacks Are Best Backpacks can't be beat for ...

  20. Asthma Basics

    Science.gov (United States)

    ... Tropical Delight: Melon Smoothie Pregnant? Your Baby's Growth Asthma Basics KidsHealth > For Parents > Asthma Basics Print A ... Asthma Categories en español Asma: aspectos fundamentales About Asthma Asthma is a common lung condition in kids ...

  1. Hygiene Basics

    Science.gov (United States)

    ... How Can I Help a Friend Who Cuts? Hygiene Basics KidsHealth > For Teens > Hygiene Basics Print A A A Text Size What's ... smell, anyway? Read below for information on some hygiene basics — and learn how to deal with greasy ...

  2. Multidrug Resistance: Physiological Principles and Nanomedical Solutions

    OpenAIRE

    Kunjachan, Sijumon; Rychlik, Błażej; Storm,Gert; Kiessling, Fabian; Lammers, Twan

    2013-01-01

    Multidrug (MDR) resistance is a pathophysiological phenomenon employed by cancer cells which limits the prolonged and effective use of chemotherapeutic agents. MDR is primarily based on the over-expression of drug efflux pumps in the cellular membrane. Prominent examples of such efflux pumps, which belong to the ATP-binding cassette (ABC) superfamily of proteins, are Pgp (P-glycoprotein) and MRP (multidrug resistance-associated protein), nowadays officially known as ABCB1 and ABCC1. Over the ...

  3. Multidrug resistance: Physiological principles and nanomedical solutions

    NARCIS (Netherlands)

    Kunjachan, S.; Rychlik, B.; Storm, G.; Kiessling, F.; Lammers, T.G.G.M.

    2013-01-01

    Multidrug resistance (MDR) is a pathophysiological phenomenon employed by cancer cells which limits the prolonged and effective use of chemotherapeutic agents. MDR is primarily based on the over-expression of drug efflux pumps in the cellular membrane. Prominent examples of such efflux pumps, which

  4. Integrating the Carbon and Water Footprints’ Costs in the Water Framework Directive 2000/60/EC Full Water Cost Recovery Concept: Basic Principles Towards Their Reliable Calculation and Socially Just Allocation

    Directory of Open Access Journals (Sweden)

    Anastasia Papadopoulou

    2012-01-01

    Full Text Available This paper presents the basic principles for the integration of the water and carbon footprints cost into the resource and environmental costs respectively, taking the suggestions set by the Water Framework Directive (WFD 2000/60/EC one step forward. WFD states that full water cost recovery (FWCR should be based on the estimation of the three sub-costs related: direct; environmental; and resource cost. It also strongly suggests the EU Member States develop and apply effective water pricing policies to achieve FWCR. These policies must be socially just to avoid any social injustice phenomena. This is a very delicate task to handle, especially within the fragile economic conditions that the EU is facing today. Water losses play a crucial role for the FWC estimation. Water losses should not be neglected since they are one of the major “water uses” in any water supply network. A methodology is suggested to reduce water losses and the related Non Revenue Water (NRW index. An Expert Decision Support System is proposed to assess the FWC incorporating the Water and Carbon Footprint costs.

  5. 高职院校学生职业技能培训程序及原则%On Students' Vocational Skill Training Program and its Basic Principles in Higher Vocational Colleges

    Institute of Scientific and Technical Information of China (English)

    肖凤翔; 马良军

    2012-01-01

    Vocational skill training is the primary content for higher vocational education. Besides the emphasis on operational vocational training in training program design, more attention should be paid on the developing of relative cognitive competence. To explore and design the vocational training program and its basic principles for higher vocational colleges as well as the analysis of psychological basis and its formation stage for vocational skills are groundwork. To define vocational training mechanism based on the above procedures, the quality of vocational skill training can be improved.%职业技能培训是高等职业教育的主要内容。在培训程序设计中除强调操作性职业技能训练外,还应更加注意发展与之相关的认知能力。探索并设计高等职业学校学生职业技能培训程序及其基本原则,分析职业技能的心理基础及其形成阶段是基础性工作,在此基础上,明确职业技能训练机理,才能提高学生职业技能培训的质量。

  6. Children and Their Basic Needs.

    Science.gov (United States)

    Prince, Debra Lindsey; Howard, Esther M.

    2002-01-01

    Describes obstacles presented by poverty in the fulfillment of the basic needs of children. Individually addresses Maslow's five basic needs with regard to children reared in poverty: (1) physiological needs; (2) safety needs; (3) belonging and love needs; (4) self-esteem needs; and (5) self-actualization needs. (Author/SD)

  7. Basic electrotechnology

    CERN Document Server

    Ashen, R A

    2013-01-01

    BASIC Electrotechnology discusses the applications of Beginner's All-purpose Symbolic Instruction Code (BASIC) in engineering, particularly in solving electrotechnology-related problems. The book is comprised of six chapters that cover several topics relevant to BASIC and electrotechnology. Chapter 1 provides an introduction to BASIC, and Chapter 2 talks about the use of complex numbers in a.c. circuit analysis. Chapter 3 covers linear circuit analysis with d.c. and sinusoidal a.c. supplies. The book also discusses the elementary magnetic circuit theory. The theory and performance of two windi

  8. PRINCIPLES OF ANIMAL BREEDING

    OpenAIRE

    Sonja Jovanovac

    2014-01-01

    University textbook Principles of Animal Breeding is intended for students of agriculture and veterinary medicine. The material is the adapted curricula of undergraduate and graduate level studies in the framework of which the modules Principles of animal breeding as well as Basics of genetics and selection of animals attended are listened. The textbook contains 14 chapters and a glossary of terms. Its concept enables combining fundamental and modern knowledge in the ...

  9. Brain Basics

    Medline Plus

    Full Text Available ... related to changes in the anatomy, physiology, and chemistry of the nervous system. When the brain cannot ... husband questions about Sarah's symptoms and family medical history. Epigenetic changes from stress or early-life experiences ...

  10. Brain Basics

    Medline Plus

    Full Text Available ... related to changes in the anatomy, physiology, and chemistry of the nervous system. When the brain cannot ... NIMH Strategic Plan in 2016 August 31, 2016, 2:00-3:00 PM ET General Health Information ...

  11. Brain Basics

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    Full Text Available ... can be related to changes in the anatomy, physiology, and chemistry of the nervous system. When the ... healthy people, and how normal brain development and function can go awry, leading to mental illnesses. Brain ...

  12. Brain Basics

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    Full Text Available ... they can be related to changes in the anatomy, physiology, and chemistry of the nervous system. When the brain cannot effectively coordinate the billions of cells in the body, the results can affect many aspects of life. ...

  13. Brain Basics

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    Full Text Available ... Feeds About Us About Us Home Director’s Blog Budget Strategic Plan Offices and Divisions Careers@NIMH Advisory ... Evidence shows that they can be related to changes in the anatomy, physiology, and chemistry of the ...

  14. Brain Basics

    Medline Plus

    Full Text Available ... related to changes in the anatomy, physiology, and chemistry of the nervous system. When the brain cannot ... who can diagnose mental disorders are psychologists or clinical social workers. The psychiatrist asked Sarah and her ...

  15. Back to basics audio

    CERN Document Server

    Nathan, Julian

    1998-01-01

    Back to Basics Audio is a thorough, yet approachable handbook on audio electronics theory and equipment. The first part of the book discusses electrical and audio principles. Those principles form a basis for understanding the operation of equipment and systems, covered in the second section. Finally, the author addresses planning and installation of a home audio system.Julian Nathan joined the audio service and manufacturing industry in 1954 and moved into motion picture engineering and production in 1960. He installed and operated recording theaters in Sydney, Austra

  16. Brain Basics

    Medline Plus

    Full Text Available ... in Real Life Brain Research Glossary Brain Basics (PDF, 10 pages) Introduction Watch the Brain Basics video ... early brain development, and may also assist in learning and memory. ... rise to disabilities or diseases. neural circuit —A network of neurons ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... pituitary-adrenal (HPA) axis. Brain Basics in Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah ... having trouble coping with the stresses in her life. She began to think of suicide because she ...

  18. Brain Basics

    Medline Plus

    Full Text Available ... Basics will introduce you to some of this science, such as: How the brain develops How genes and the environment affect the brain The basic structure of the brain How different parts of the brain communicate and work with each other How changes in the brain ...

  19. Brain Basics

    Medline Plus

    Full Text Available ... Basics in Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a middle-aged woman who seemed to have it all. She was happily married and successful in business. Then, after a serious setback at work, she lost interest ...

  20. BASIC Programming.

    Science.gov (United States)

    Jennings, Carol Ann

    Designed for use by both secondary- and postsecondary-level business teachers, this curriculum guide consists of 10 units of instructional materials dealing with Beginners All-Purpose Symbol Instruction Code (BASIC) programing. Topics of the individual lessons are numbering BASIC programs and using the PRINT, END, and REM statements; system…

  1. Brain Basics

    Medline Plus

    Full Text Available ... Basics in Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a ... medical history. Epigenetic changes from stress or early-life experiences ... In contrast, major depression is a serious disorder that lasts for weeks. ...

  2. Rowing Physiology.

    Science.gov (United States)

    Spinks, W. L.

    This review of the literature discusses and examines the methods used in physiological assessment of rowers, results of such assessments, and future directions emanating from research in the physiology of rowing. The first section discusses the energy demands of rowing, including the contribution of the energy system, anaerobic metabolism, and the…

  3. Basics of statistical physics

    CERN Document Server

    Müller-Kirsten, Harald J W

    2013-01-01

    Statistics links microscopic and macroscopic phenomena, and requires for this reason a large number of microscopic elements like atoms. The results are values of maximum probability or of averaging. This introduction to statistical physics concentrates on the basic principles, and attempts to explain these in simple terms supplemented by numerous examples. These basic principles include the difference between classical and quantum statistics, a priori probabilities as related to degeneracies, the vital aspect of indistinguishability as compared with distinguishability in classical physics, the differences between conserved and non-conserved elements, the different ways of counting arrangements in the three statistics (Maxwell-Boltzmann, Fermi-Dirac, Bose-Einstein), the difference between maximization of the number of arrangements of elements, and averaging in the Darwin-Fowler method. Significant applications to solids, radiation and electrons in metals are treated in separate chapters, as well as Bose-Eins...

  4. Variational principles in physics

    CERN Document Server

    Basdevant, Jean-Louis

    2007-01-01

    Optimization under constraints is an essential part of everyday life. Indeed, we routinely solve problems by striking a balance between contradictory interests, individual desires and material contingencies. This notion of equilibrium was dear to thinkers of the enlightenment, as illustrated by Montesquieu’s famous formulation: "In all magistracies, the greatness of the power must be compensated by the brevity of the duration." Astonishingly, natural laws are guided by a similar principle. Variational principles have proven to be surprisingly fertile. For example, Fermat used variational methods to demonstrate that light follows the fastest route from one point to another, an idea which came to be known as Fermat’s principle, a cornerstone of geometrical optics. Variational Principles in Physics explains variational principles and charts their use throughout modern physics. The heart of the book is devoted to the analytical mechanics of Lagrange and Hamilton, the basic tools of any physicist. Prof. Basdev...

  5. Human physiology in space

    Science.gov (United States)

    Vernikos, J.

    1996-01-01

    The universality of gravity (1 g) in our daily lives makes it difficult to appreciate its importance in morphology and physiology. Bone and muscle support systems were created, cellular pumps developed, neurons organised and receptors and transducers of gravitational force to biologically relevant signals evolved under 1g gravity. Spaceflight provides the only microgravity environment where systematic experimentation can expand our basic understanding of gravitational physiology and perhaps provide new insights into normal physiology and disease processes. These include the surprising extent of our body's dependence on perceptual information, and understanding the effect and importance of forces generated within the body's weightbearing structures such as muscle and bones. Beyond this exciting prospect is the importance of this work towards opening the solar system for human exploration. Although both appear promising, we are only just beginning to taste what lies ahead.

  6. Brain Basics

    Medline Plus

    Full Text Available ... The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are the basic working unit of the ... distant nerve cells (via axons) to form brain circuits. These circuits control specific body functions such as ...

  7. Brain Basics

    Medline Plus

    Full Text Available ... News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The Working Brain ... to mental disorders, such as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are ...

  8. Brain Basics

    Medline Plus

    Full Text Available ... Trials — Participants Statistics Help for Mental Illnesses Outreach Research Priorities Funding Labs at NIMH News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The ...

  9. Brain Basics

    Medline Plus

    Full Text Available ... normal brain development and function can go awry, leading to mental illnesses. Brain Basics will introduce you ... of DNA. Sometimes this copying process is imperfect, leading to a gene mutation that causes the gene ...

  10. Brain Basics

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    Full Text Available ... Brain Basics will introduce you to some of this science, such as: How the brain develops How ... cell, and responds to signals from the environment; this all helps the cell maintain its balance with ...

  11. Brain Basics

    Medline Plus

    Full Text Available ... Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a middle- ... However, recent research points to a possible new class of antidepressants that can relieve symptoms of the ...

  12. Brain Basics

    Medline Plus

    Full Text Available ... for the function of conducting messages. A neuron has three basic parts: Cell body which includes the ... disorder (ADHD) . Glutamate —the most common neurotransmitter, glutamate has many roles throughout the brain and nervous system. ...

  13. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... others live with symptoms of mental illness every day. They can be moderate, or serious and cause ...

  14. Brain Basics

    Science.gov (United States)

    ... News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The Working Brain ... to mental disorders, such as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are ...

  15. Brain Basics

    Medline Plus

    Full Text Available ... the function of conducting messages. A neuron has three basic parts: Cell body which includes the nucleus, ... Plan in 2016 August 31, 2016, 2:00-3:00 PM ET Recovery Month September 2016 National ...

  16. Basic Finance

    Science.gov (United States)

    Vittek, J. F.

    1972-01-01

    A discussion of the basic measures of corporate financial strength, and the sources of the information is reported. Considered are: balance sheet, income statement, funds and cash flow, and financial ratios.

  17. Cancer Basics

    Science.gov (United States)

    ... Cancer? Breast Cancer Colon/Rectum Cancer Lung Cancer Prostate Cancer Skin Cancer Show All Cancer Types News and Features Cancer Glossary ACS Bookstore Cancer Information Cancer Basics Cancer Prevention & Detection Signs & Symptoms of Cancer Treatments & Side Effects ...

  18. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... learning more about how the brain grows and works in healthy people, and how normal brain development ...

  19. Blood Basics

    Science.gov (United States)

    ... Patient Group Links Advocacy Toolkit Home For Patients Blood Basics Blood is a specialized body fluid. It ... about 9 pints. Jump To: The Components of Blood and Their Importance Many people have undergone blood ...

  20. Brain Basics

    Medline Plus

    Full Text Available ... Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a ... volunteers PubMed Central: An archive of life sciences journals NIH Research Fact Sheets NIH Office of Science ...

  1. Brain Basics

    Medline Plus

    Full Text Available ... How the brain develops How genes and the environment affect the brain The basic structure of the ... inside contents of the cell from its surrounding environment and controls what enters and leaves the cell, ...

  2. Brain Basics

    Medline Plus

    Full Text Available ... and the environment affect the brain The basic structure of the brain How different parts of the ... for the cell to work properly including small structures called cell organelles. Dendrites branch off from the ...

  3. Brain Basics

    Medline Plus

    Full Text Available ... science, such as: How the brain develops How genes and the environment affect the brain The basic ... that with brain development in people mental disorders. Genes and environmental cues both help to direct this ...

  4. Brain Basics

    Medline Plus

    Full Text Available ... interconnections. neuron —A nerve cell that is the basic, working unit of the brain and nervous system, which processes and transmits information. neurotransmitter —A chemical produced by ...

  5. Brain Basics

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    Full Text Available ... Real Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a ... blues" from time to time. In contrast, major depression is a serious disorder that lasts for weeks. ...

  6. Body Basics

    Science.gov (United States)

    ... about how the body works, what basic human anatomy is, and what happens when parts of the body don't function properly. Blood Bones, Muscles, and Joints Brain and Nervous System Digestive System Endocrine System Eyes Female Reproductive System ...

  7. Brain Basics

    Medline Plus

    Full Text Available ... Health & Education Mental Health Information Publications Educational Resources Clinical Trials — Participants Statistics Help for Mental Illnesses Outreach Research Priorities Funding Labs at NIMH News About Us Home > Health & Education > Educational Resources Brain Basics Introduction ...

  8. Principles of Bridge Reliability

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle; Nowak, Andrzej S.

    The paper gives a brief introduction to the basic principles of structural reliability theory and its application to bridge engineering. Fundamental concepts like failure probability and reliability index are introduced. Ultimate as well as serviceability limit states for bridges are formulated...

  9. Brain Basics

    Medline Plus

    Full Text Available ... brain disorders. Evidence shows that they can be related to changes in the anatomy, physiology, and chemistry ... MEDLINEPlus : Authoritative information from government agencies and health-related organizations, available in both English and Spanish ( Español ) ...

  10. Physiological parameters

    International Nuclear Information System (INIS)

    The physiological characteristics of man depend on the intake, metabolism and excretion of stable elements from food, water, and air. The physiological behavior of natural radionuclides and radionuclides from nuclear weapons testing and from the utilization of nuclear energy is believed to follow the pattern of stable elements. Hence information on the normal physiological processes occurring in the human body plays an important role in the assessment of the radiation dose received by man. Two important physiological parameters needed for internal dose determination are the pulmonary function and the water balance. In the Coordinated Research Programme on the characterization of Asian population, five participants submitted data on these physiological characteristics - China, India, Japan, Philippines and Viet Nam. During the CRP, data on other pertinent characteristics such as physical and dietary were simultaneously being collected. Hence, the information on the physiological characteristics alone, coming from the five participants were not complete and are probably not sufficient to establish standard values for the Reference Asian Man. Nonetheless, the data collected is a valuable contribution to this research programme

  11. Causality Principle

    OpenAIRE

    Chi, Do Minh

    2001-01-01

    We advance a famous principle - causality principle - but under a new view. This principle is a principium automatically leading to most fundamental laws of the nature. It is the inner origin of variation, rules evolutionary processes of things, and the answer of the quest for ultimate theories of the Universe.

  12. Basic electronics

    CERN Document Server

    Holbrook, Harold D

    1971-01-01

    Basic Electronics is an elementary text designed for basic instruction in electricity and electronics. It gives emphasis on electronic emission and the vacuum tube and shows transistor circuits in parallel with electron tube circuits. This book also demonstrates how the transistor merely replaces the tube, with proper change of circuit constants as required. Many problems are presented at the end of each chapter. This book is comprised of 17 chapters and opens with an overview of electron theory, followed by a discussion on resistance, inductance, and capacitance, along with their effects on t

  13. How can a basic income be defended?

    OpenAIRE

    Allegre, Guillaume

    2014-01-01

    Following the submission of 125,000 signatures collected by organizations (including BIEN Suisse) supporting the establishment of a basic income, Swiss citizens will vote in a referendum on a popular initiative to include the principle of an unconditional basic income in the Swiss Federal Constitution. While a basic income, which is defended by Vanderborght and Van Parijs (2005) under the term "universal allocation", can take many forms, its principles are that it is paid (1) on a universal b...

  14. Ideario Educativo (Principles of Education).

    Science.gov (United States)

    Consejo Nacional Tecnico de la Educacion (Mexico).

    This document is an English-language abstract (approximately 1,500 words) which discusses an overall educational policy for Mexico based on Constitutional principles and those of humanism. The basic principles that should guide Mexican education as seen by the National Technical Council for Education are the following: (1) love of country; (2)…

  15. Magnesium basics

    OpenAIRE

    Jahnen-Dechent, Wilhelm; Ketteler, Markus

    2012-01-01

    As a cofactor in numerous enzymatic reactions, magnesium fulfils various intracellular physiological functions. Thus, imbalance in magnesium status—primarily hypomagnesaemia as it is seen more often than hypermagnesaemia—might result in unwanted neuromuscular, cardiac or nervous disorders. Measuring total serum magnesium is a feasible and affordable way to monitor changes in magnesium status, although it does not necessarily reflect total body magnesium content. The following review focuses o...

  16. Physiological breeding.

    Science.gov (United States)

    Reynolds, Matthew; Langridge, Peter

    2016-06-01

    Physiological breeding crosses parents with different complex but complementary traits to achieve cumulative gene action for yield, while selecting progeny using remote sensing, possibly in combination with genomic selection. Physiological approaches have already demonstrated significant genetic gains in Australia and several developing countries of the International Wheat Improvement Network. The techniques involved (see Graphical Abstract) also provide platforms for research and refinement of breeding methodologies. Recent examples of these include screening genetic resources for novel expression of Calvin cycle enzymes, identification of common genetic bases for heat and drought adaptation, and genetic dissection of trade-offs among yield components. Such information, combined with results from physiological crosses designed to test novel trait combinations, lead to more precise breeding strategies, and feed models of genotype-by-environment interaction to help build new plant types and experimental environments for future climates. PMID:27161822

  17. Regulatory Physiology

    Science.gov (United States)

    Lane, Helen W.; Whitson, Peggy A.; Putcha, Lakshmi; Baker, Ellen; Smith, Scott M.; Stewart, Karen; Gretebeck, Randall; Nimmagudda, R. R.; Schoeller, Dale A.; Davis-Street, Janis

    1999-01-01

    As noted elsewhere in this report, a central goal of the Extended Duration Orbiter Medical Project (EDOMP) was to ensure that cardiovascular and muscle function were adequate to perform an emergency egress after 16 days of spaceflight. The goals of the Regulatory Physiology component of the EDOMP were to identify and subsequently ameliorate those biochemical and nutritional factors that deplete physiological reserves or increase risk for disease, and to facilitate the development of effective muscle, exercise, and cardiovascular countermeasures. The component investigations designed to meet these goals focused on biochemical and physiological aspects of nutrition and metabolism, the risk of renal (kidney) stone formation, gastrointestinal function, and sleep in space. Investigations involved both ground-based protocols to validate proposed methods and flight studies to test those methods. Two hardware tests were also completed.

  18. The working principle of magnetic resonance therapy

    CERN Document Server

    Brizhik, Larissa; Fermi, Enrico

    2015-01-01

    In this paper we describe briefly the basic aspects of magnetic resonance therapy, registered as TMR therapy. Clinical studies have shown that application of this therapy significantly accelerates wound healing and, in particular, healing of the diabetic foot disease. To understand the working principle of this therapy, we analyze relevant to it biological effects produced by magnetic fields. Based on these data, we show that there is a hierarchy of the possible physical mechanisms, which can produce such effects. The mutual interplay between the mechanisms can lead to a synergetic outcome delayed in time, which can affect the physiological state of the organism. In particular, we show that soliton mediated charge transport during the redox processes in living organisms is sensitive to magnetic fields, so that such fields can facilitate redox processes in particular, and can stimulate the healing effect of the organism in general. This and other non-thermal resonant mechanisms of the biological effects of mag...

  19. Brain Basics

    Medline Plus

    Full Text Available ... Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a middle-aged woman ... new memories. hypothalmic-pituitary-adrenal (HPA) axis —A brain-body ... stress. impulse —An electrical communication signal sent between neurons ...

  20. Basic Skills.

    Science.gov (United States)

    Luparelli, Augustus N.; And Others

    1981-01-01

    These four articles focus on developing basic reading, science, and job search skills: "Reading Program for Vocational Classes" by Augustus Luparelli; "Why Teach Employability Skills?" by Larry Siefferman; "Improving Vocabulary and Reading Skills" by Edythe Conway; and "Science in Everyday Life" by Virginia Eleazer and George Carney. (SK)

  1. Brain Basics

    Medline Plus

    Full Text Available ... will fire. This enhances the electrical flow among brain cells required for normal function and plays an important ... of neurons and their interconnections. neuron —A nerve cell that is the basic, working unit of the brain and nervous system, which processes and transmits information. ...

  2. Brain Basics

    Medline Plus

    Full Text Available ... Welcome. Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... highly developed area at the front of the brain that, in humans, plays a role in executive functions such as ...

  3. Ethanol Basics

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-01-30

    Ethanol is a widely-used, domestically-produced renewable fuel made from corn and other plant materials. More than 96% of gasoline sold in the United States contains ethanol. Learn more about this alternative fuel in the Ethanol Basics Fact Sheet, produced by the U.S. Department of Energy's Clean Cities program.

  4. Basic Backwardness.

    Science.gov (United States)

    Weingartner, Charles

    This paper argues that the "back to basics" movement is regressive and that regression is the characteristic mode of fear-ridden personalities. It is argued that many people in American society today have lost their ability to laugh and do not have the sense of humor which is crucial to a healthy mental state. Such topics as necrophilia, mental…

  5. Biological Energy Based on the Principles of Photosynthesis from Basic Theory to Energy Application%基于光合作用的生物能源从基础研究到应用

    Institute of Scientific and Technical Information of China (English)

    杨春虹; 常文瑞

    2011-01-01

    The global climate and environmental problems caused by increasing consumption of fossil fuels have greatly accelerated the development of new technologies for clean and sustainable energy based on solar energy. How to harness solar energy and transform it efficiently to energy forms which can be used directly by the mankind has long been the most basic scientific problem of global concern. In the history of science and technology; it is common that imitating the nature often inspires new technologies. For example; inspired by imitating the flight of birds; the mankind has created the aeroplanes within less than a century. The most effective process of harnessing solar energy is the photosynthesis; which has reached its perfection in nature after over 3.5 billion years evolution. Photosynthesis is the most effective process to harness; transport and convert solar energy into chemical energy. Photosynthesis happens in chloroplast where occur a serious of activities; e.g.; harnessing solar energy; splitting water and produce oxygen and carbohydrates. This observation has caused the inspiration that it is possible for the mankind to imitate photosynthesis and to harness and transform solar energy effectively. The article has introduced the principles of how to solve the energy and environmental problems through artificial photosynthesis. Based on these observations; it has discussed the perspective of using the principle of photosynthesis to collect solar energy by means of imitating the process of photosynthesis to produce clean and sustainable energy.%化石能源的大量消耗,以及由此带来的全球气候和环境问题,推动了以太阳能为基础的新型清洁能源的研究.长期以来,如何有效地捕获太阳能,并将其高效率地转化成人类可以直接利用的能源,一直是太阳能利用中最基础的科学问题,得到了全世界的广泛关注.科学技术的发展史说明,人类从认识自然、模仿自然规律开始,已经创

  6. Teaching/learning principles

    Science.gov (United States)

    Hankins, D. B.; Wake, W. H.

    1981-01-01

    The potential remote sensing user community is enormous, and the teaching and training tasks are even larger; however, some underlying principles may be synthesized and applied at all levels from elementary school children to sophisticated and knowledgeable adults. The basic rules applying to each of the six major elements of any training course and the underlying principle involved in each rule are summarized. The six identified major elements are: (1) field sites for problems and practice; (2) lectures and inside study; (3) learning materials and resources (the kit); (4) the field experience; (5) laboratory sessions; and (6) testing and evaluation.

  7. Electrical principles 3 checkbook

    CERN Document Server

    Bird, J O

    2013-01-01

    Electrical Principles 3 Checkbook aims to introduce students to the basic electrical principles needed by technicians in electrical engineering, electronics, and telecommunications.The book first tackles circuit theorems, single-phase series A.C. circuits, and single-phase parallel A.C. circuits. Discussions focus on worked problems on parallel A.C. circuits, worked problems on series A.C. circuits, main points concerned with D.C. circuit analysis, worked problems on circuit theorems, and further problems on circuit theorems. The manuscript then examines three-phase systems and D.C. transients

  8. Basic plasma physics

    CERN Document Server

    Ghosh, Basudev

    2014-01-01

    Basic Plasma Physics is designed to serve as an introductory compact textbook for advanced undergraduate, postgraduate and research students taking plasma physics as one of their subject of study for the first time. It covers the current syllabus of plasma physics offered by the most universities and technical institutions. The book requires no background in plasma physics but only elementary knowledge of basic physics and mathematics. Emphasis has been given on the analytical approach. Topics are developed from first principle so that the students can learn through self-study. One chapter has been devoted to describe some practical aspects of plasma physics. Each chapter contains a good number of solved and unsolved problems and a variety of review questions, mostly taken from recent examination papers. Some classroom experiments described in the book will surely help students as well as instructors.

  9. A graphical simulation software for instruction in cardiovascular mechanics physiology

    Directory of Open Access Journals (Sweden)

    Wenger Roland H

    2011-01-01

    Full Text Available Abstract Background Computer supported, interactive e-learning systems are widely used in the teaching of physiology. However, the currently available complimentary software tools in the field of the physiology of cardiovascular mechanics have not yet been adapted to the latest systems software. Therefore, a simple-to-use replacement for undergraduate and graduate students' education was needed, including an up-to-date graphical software that is validated and field-tested. Methods Software compatible to Windows, based on modified versions of existing mathematical algorithms, has been newly developed. Testing was performed during a full term of physiological lecturing to medical and biology students. Results The newly developed CLabUZH software models a reduced human cardiovascular loop containing all basic compartments: an isolated heart including an artificial electrical stimulator, main vessels and the peripheral resistive components. Students can alter several physiological parameters interactively. The resulting output variables are printed in x-y diagrams and in addition shown in an animated, graphical model. CLabUZH offers insight into the relations of volume, pressure and time dependency in the circulation and their correlation to the electrocardiogram (ECG. Established mechanisms such as the Frank-Starling Law or the Windkessel Effect are considered in this model. The CLabUZH software is self-contained with no extra installation required and runs on most of today's personal computer systems. Conclusions CLabUZH is a user-friendly interactive computer programme that has proved to be useful in teaching the basic physiological principles of heart mechanics.

  10. Separating the basic logics of the basic recurrences

    CERN Document Server

    Japaridze, Giorgi

    2010-01-01

    This paper shows that, even at the most basic level (namely, in combination with only $\\gneg,\\mlc,\\mld$), the parallel, countable branching and uncountable branching recurrences of computability logic (see http://www.cis.upenn.edu/~giorgi/cl.html) validate different principles.

  11. Environmental physiology

    International Nuclear Information System (INIS)

    Summaries of research projects conducted during 1978 and 1979 are presented. Subject areas include: the effects of environmental pollutants on homeostasis of the hematopoietic system; pollutant effects on steroid metabolism; pollutant effects on pulmonary macrophages; effects of toxic gases on lung cells; the development of immunological methods for assessing lung damage at the cellular level; the response of erythropoietin concentration to various physiological changes; and the study of actinide metabolism in monkey skeletons

  12. Regression Basics

    CERN Document Server

    Kahane, Leo H

    2007-01-01

    Using a friendly, nontechnical approach, the Second Edition of Regression Basics introduces readers to the fundamentals of regression. Accessible to anyone with an introductory statistics background, this book builds from a simple two-variable model to a model of greater complexity. Author Leo H. Kahane weaves four engaging examples throughout the text to illustrate not only the techniques of regression but also how this empirical tool can be applied in creative ways to consider a broad array of topics. New to the Second Edition Offers greater coverage of simple panel-data estimation:

  13. Epidemiology and Pulmonary Physiology of Severe Asthma.

    Science.gov (United States)

    O'Toole, Jacqueline; Mikulic, Lucas; Kaminsky, David A

    2016-08-01

    The epidemiology and physiology of severe asthma are inherently linked because of varying phenotypes and expressions of asthma throughout the population. To understand how to better treat severe asthma, we must use both population data and physiologic principles to individualize therapies among groups with similar expressions of this disease. PMID:27401616

  14. Principles of Safety Pharmacology

    OpenAIRE

    Pugsley, M. K.; Authier, S; Curtis, M J

    2008-01-01

    Safety Pharmacology is a rapidly developing discipline that uses the basic principles of pharmacology in a regulatory-driven process to generate data to inform risk/benefit assessment. The aim of Safety Pharmacology is to characterize the pharmacodynamic/pharmacokinetic (PK/PD) relationship of a drug's adverse effects using continuously evolving methodology. Unlike toxicology, Safety Pharmacology includes within its remit a regulatory requirement to predict the risk of rare lethal events. Thi...

  15. General Principles Governing Liability

    International Nuclear Information System (INIS)

    This paper contains a brief review of the basic principles which govern the special regime of liability and compensation for nuclear damage originating on nuclear installations, in particular the strict and exclusive liability of the nuclear operator, the provision of a financial security to cover this liability and the limits applicable both in amount and in time. The paper also reviews the most important international agreements currently in force which constitute the foundation of this special regime. (author)

  16. Paediatric airway management: basic aspects

    DEFF Research Database (Denmark)

    Holm-Knudsen, R J; Rasmussen, L S

    2009-01-01

    children. This paper aims at providing the non-paediatric anaesthesiologist with a set of safe and simple principles for basic paediatric airway management. In contrast to adults, most children with difficult airways are recognised before induction of anaesthesia but problems may arise in all children...

  17. Physiological and functional magnetic resonance imaging using balanced steady-state free precession

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sung Hong; Han, Paul Kyu [Magnetic Resonance Imaging Lab, Dept. of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon(Korea, Republic of); Choi, Seung Hong [Dept. of Radiology, Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2015-06-15

    Balanced steady-state free precession (bSSFP) is a highly efficient pulse sequence that is known to provide the highest signal-to-noise ratio per unit time. Recently, bSSFP is getting increasingly popular in both the research and clinical communities. This review will be focusing on the application of the bSSFP technique in the context of probing the physiological and functional information. In the first part of this review, the basic principles of bSSFP are briefly covered. Afterwards, recent developments related to the application of bSSFP, in terms of physiological and functional imaging, are introduced and reviewed. Despite its long development history, bSSFP is still a promising technique that has many potential benefits for obtaining high-resolution physiological and functional images.

  18. Gamma-Ray Telescope and Uncertainty Principle

    Science.gov (United States)

    Shivalingaswamy, T.; Kagali, B. A.

    2012-01-01

    Heisenberg's Uncertainty Principle is one of the important basic principles of quantum mechanics. In most of the books on quantum mechanics, this uncertainty principle is generally illustrated with the help of a gamma ray microscope, wherein neither the image formation criterion nor the lens properties are taken into account. Thus a better…

  19. 格“知”穷理知行互发——读李扬教授《知识产权法基本原理》%Study of the Nature of Intellectual Property Law from Theories to Actions -Review for Professor Li Yang's Basic Principles of the Intellectual Property Law

    Institute of Scientific and Technical Information of China (English)

    朱与墨

    2012-01-01

    Professor Li Yang's Basic Principles of the Intellectual Property Law embodies his thoughts of legal idea on intellectual property, intellectual property special law, anti - unfair competition law, the integral intellectual property law thought of the civil law by elab- orating the basic theory in the civil law. In order to guide practice, the author explored the basic principles of intellectual property law. This book has the characteristics of theoretical cornerstone, systematic originality, guiding practice, prospective criticism and enlightenment lesson.%李扬教授的《知识产权法基本原理》在民法的基本理论上展开,集中反映了李扬教授的知识产权法定主义观念、知识产权法——反不正当竞争法——民法位阶顺序的整体性知识产权法思想。作者探究知识产权法理本原,以求指导实践,具有理论基石性、内容体系的独创性、实务指导性、批判前瞻性、借鉴启迪性等特点。

  20. Basic research projects

    International Nuclear Information System (INIS)

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined

  1. Basic research projects

    Energy Technology Data Exchange (ETDEWEB)

    1979-04-01

    The research programs under the cognizance of the Office of Energy Research (OER) are directed toward discovery of natural laws and new knowledge, and to improved understanding of the physical and biological sciences as related to the development, use, and control of energy. The ultimate goal is to develop a scientific underlay for the overall DOE effort and the fundamental principles of natural phenomena so that these phenomena may be understood, and new principles, formulated. The DOE-OER outlay activities include three major programs: High Energy Physics, Nuclear Physics, and Basic Energy Sciences. Taken together, these programs represent some 30 percent of the Nation's Federal support of basic research in the energy sciences. The research activities of OER involve more than 6,000 scientists and engineers working in some 17 major Federal Research Centers and at more than 135 different universities and industrial firms throughout the United States. Contract holders in the areas of high-energy physics, nuclear physics, materials sciences, nuclear science, chemical sciences, engineering, mathematics geosciences, advanced energy projects, and biological energy research are listed. Funding trends for recent years are outlined. (RWR)

  2. Regulatory physiology discipline science plan

    Science.gov (United States)

    1991-01-01

    The focus of the Regulatory Physiology discipline of the Space Physiology and Countermeasures Program is twofold. First, to determine and study how microgravity and associated factors of space flight affect the regulatory mechanisms by which humans adapt and achieve homeostasis and thereby regulate their ability to respond to internal and external signals; and, second, to study selected physiological systems that have been demonstrated to be influenced by gravity. The Regulatory Physiology discipline, as defined here, is composed of seven subdisciplines: (1) Circadian Rhythms, (2) Endocrinology, (3) Fluid and Electrolyte Regulation, (4) Hematology, (5) Immunology, (6) Metabolism and Nutrition, and (7) Temperature Regulation. The purpose of this Discipline Science Plan is to provide a conceptual strategy for NASA's Life Sciences Division research and development activities in the area of regulatory physiology. It covers the research areas critical to NASA's programmatic requirements for the Extended-Duration Orbiter, Space Station Freedom, and exploration mission science activities. These science activities include ground-based and flight; basic, applied, and operational; and animal and human research and development. This document summarizes the current status of the program, outlines available knowledge, establishes goals and objectives, identifies science priorities, and defines critical questions in regulatory physiology. It contains a general plan that will be used by both NASA Headquarters Program Offices and the field centers to review and plan basic, applied, and operational intramural and extramural research and development activities in this area.

  3. Exercise physiology

    DEFF Research Database (Denmark)

    Kiens, Bente; Richter, Erik; Wojtaszewski, Jørgen

    2014-01-01

    The passing of Professor Bengt Saltin on September 12, 2014 truly marks the end of an era. As editor of the Journal of Applied Physiology and one of Bengt’s many collaborators and colleagues, I wanted the Journal to celebrate his many seminal contributions by means of an Editorial. Professor Bent...... Kiens, who is both a colleague of Bengt’s and a Consulting Editor for the Journal, was asked to write it. Thanks to Bente and her colleagues for the impossible task of distilling an enormous body of work into about 1,000 words. Peter Wagner, Editor...

  4. Occupational physiology

    CERN Document Server

    Toomingas, Allan; Tornqvist, Ewa Wigaeus

    2011-01-01

    In a clear and accessible presentation, Occupational Physiology focuses on important issues in the modern working world. Exploring major public health problems-such as musculoskeletal disorders and stress-this book explains connections between work, well-being, and health based on up-to-date research in the field. It provides useful methods for risk assessment and guidelines on arranging a good working life from the perspective of the working individual, the company, and society as a whole.The book focuses on common, stressful situations in different professions. Reviewing bodily demands and r

  5. Environmental physiology

    International Nuclear Information System (INIS)

    In Section 3 of this annual report the Environmental Physiology Group reports progress in several areas of research: a study of erythropoietin biogenesis and regulation of hematopoesis; the in vitro production of erythropoietin by cloned lines of erythroleukemic cells; endocrine interactions with lung tissue, and hormonal changes in response to ozone exposure; an in vitro cell culture technique for the detection and enumeration of thymic lymphocyte progenitors in the bone marrow of experimental animals; the study of magnetic field bioeffects; the study of actinide element distribution and retention in primates; and a comparison of the efficiencies of various chelating agents in facilitating the removal of Pu-238 from the skeleton, the liver, and the whole body

  6. Physiological Acoustics

    Science.gov (United States)

    Young, Eric D.

    The analysis of physiological sound in the peripheral auditory system solves three important problems. First, sound energy impinging on the head must be captured and presented to the transduction apparatus in the ear as a suitable mechanical signal; second, this mechanical signal needs to be transduced into a neural representation that can be used by the brain; third, the resulting neural representation needs to be analyzed by central neurons to extract information useful to the animal. This chapter provides an overview of some aspects of the first two of these processes. The description is entirely focused on the mammalian auditory system, primarily on human hearing and on the hearing of a few commonly used laboratory animals (mainly rodents and carnivores). Useful summaries of non-mammalian hearing are available [1]. Because of the large size of the literature, review papers are referenced wherever possible.

  7. Basics of the ionizing radiation dosimetry

    International Nuclear Information System (INIS)

    The dosimetry basic physics issues, ionizing irradiation interaction with the substance and the radiation parameter regulation principles were considered. The special attention was paid to the methods of the ionizing radiation measurement. The edition is the manual on the dosimetry principles and is intended, first of all, for the university students of the technical and engineering specialties

  8. Variational principles

    CERN Document Server

    Moiseiwitsch, B L

    2004-01-01

    This graduate-level text's primary objective is to demonstrate the expression of the equations of the various branches of mathematical physics in the succinct and elegant form of variational principles (and thereby illuminate their interrelationship). Its related intentions are to show how variational principles may be employed to determine the discrete eigenvalues for stationary state problems and to illustrate how to find the values of quantities (such as the phase shifts) that arise in the theory of scattering. Chapter-by-chapter treatment consists of analytical dynamics; optics, wave mecha

  9. Safety assessment principles for nuclear chemical plant

    International Nuclear Information System (INIS)

    The subject is covered in sections, as follows: foreword; introduction (functions of Health and Safety Executive and Nuclear Installations Inspectorate; scope of document and principles); fundamental requirements and policy; basic principles (radiological principles; principles for the evaluation of (a) radiation exposures under normal operating conditions, and (b) fault conditions and protection systems); engineering principles (general; radioactive materials control; movement of radioactive materials; radioactive waste and scrap control; radiological protection practice; protection systems; essential resources; plant containment and ventilation; plant operation; analysis of plant faults, transients and abnormal conditions; reliability analysis; external hazards; layout; installation checks and commissioning; servicing; decommissioning); management principles (the management of safety; quality assurance). (U.K.)

  10. Physiological strategies during animal diapause: lessons from brine shrimp and annual killifish.

    Science.gov (United States)

    Podrabsky, Jason E; Hand, Steven C

    2015-06-01

    Diapause is a programmed state of developmental arrest that typically occurs as part of the natural developmental progression of organisms that inhabit seasonal environments. The brine shrimp Artemia franciscana and annual killifish Austrofundulus limnaeus share strikingly similar life histories that include embryonic diapause as a means to synchronize the growth and reproduction phases of their life history to favorable environmental conditions. In both species, respiration rate is severely depressed during diapause and thus alterations in mitochondrial physiology are a key component of the suite of characters associated with cessation of development. Here, we use these two species to illustrate the basic principles of metabolic depression at the physiological and biochemical levels. It is clear that these two species use divergent molecular mechanisms to achieve the same physiological and ecological outcomes. This pattern of convergent physiological strategies supports the importance of biochemical and physiological adaptations to cope with extreme environmental stress and suggests that inferring mechanism from transcriptomics or proteomics or metabolomics alone, without rigorous follow-up at the biochemical and physiological levels, could lead to erroneous conclusions. PMID:26085666

  11. Space Physiology within an Exercise Physiology Curriculum

    Science.gov (United States)

    Carter, Jason R.; West, John B.

    2013-01-01

    Compare and contrast strategies remain common pedagogical practices within physiological education. With the support of an American Physiological Society Teaching Career Enhancement Award, we have developed a junior- or senior-level undergraduate curriculum for exercise physiology that compares and contrasts the physiological adaptations of…

  12. The physiological basis of pulmonary gas exchange: implications for clinical interpretation of arterial blood gases.

    Science.gov (United States)

    Wagner, Peter D

    2015-01-01

    The field of pulmonary gas exchange is mature, with the basic principles developed more than 60 years ago. Arterial blood gas measurements (tensions and concentrations of O₂ and CO₂) constitute a mainstay of clinical care to assess the degree of pulmonary gas exchange abnormality. However, the factors that dictate arterial blood gas values are often multifactorial and complex, with six different causes of hypoxaemia (inspiratory hypoxia, hypoventilation, ventilation/perfusion inequality, diffusion limitation, shunting and reduced mixed venous oxygenation) contributing variably to the arterial O₂ and CO₂ tension in any given patient. Blood gas values are then usually further affected by the body's abilities to compensate for gas exchange disturbances by three tactics (greater O₂ extraction, increasing ventilation and increasing cardiac output). This article explains the basic principles of gas exchange in health, mechanisms of altered gas exchange in disease, how the body compensates for abnormal gas exchange, and based on these principles, the tools available to interpret blood gas data and, quantitatively, to best understand the physiological state of each patient. This understanding is important because therapeutic intervention to improve abnormal gas exchange in any given patient needs to be based on the particular physiological mechanisms affecting gas exchange in that patient. PMID:25323225

  13. Principles of digital image synthesis

    CERN Document Server

    Glassner, Andrew S

    1995-01-01

    Image synthesis, or rendering, is a field of transformation: it changesgeometry and physics into meaningful images. Because the most popularalgorithms frequently change, it is increasingly important for researchersand implementors to have a basic understanding of the principles of imagesynthesis. Focusing on theory, Andrew Glassner provides a comprehensiveexplanation of the three core fields of study that come together to formdigital image synthesis: the human visual system, digital signalprocessing, and the interaction of matter and light. Assuming no more thana basic background in calculus,

  14. PEOPLE AS THE CENTER-BASIC PRINCIPLE OF SPORT DEVELOPMENT IN NEW CENTUR%“以人为本”--新世纪体育发展的基本理念

    Institute of Scientific and Technical Information of China (English)

    裴立新

    2001-01-01

    采用文献和逻辑方法, 综述了20世纪人类发展观由“以物为中心”向“以人为中心”的转变进程,阐述了马克思主 义关于人与社会协调发展的思想内涵,分析了新世纪我国提出的“以人为本”促进经济和社 会协调发展,提高人民生活质量的指导思想,对“以人为本”作为新世纪体育发展理念的背 景和理论基础作出客观判断,旨在理性地认识新世纪体育事业的发展。%The aim of this article is to understand reasoningly the development of sport in the new century by literature and logica l analysis method. It was described the change of mankind's developmental view from Material as Cen ter to People as Center during 20 century. The article was explained Marxism con notation about harmonious development of people and society. It was also analyze d people as center that was provided as principle for improving life quality and harmonious development. The article was estimated objectively background and th eoretic essence of people as center as principle of sport development in the new century.

  15. Operationalization of Basic Observables in Mechanics

    CERN Document Server

    Hartmann, Bruno

    2015-01-01

    This novel approach to the foundation of the physical theory begins with thought experiments on measurement practice like Einstein for relativistic Kinematics. For a similar foundation of Dynamics one can start from Hermann von Helmholtz analysis of basic measurements. We define energy, momentum and mass from elemental ordering relations for "capability to execute work" and "impact" in a collision and apply Helmholtz program for quantification. From simple pre-theoretic (principle of inertia, impossibility of Perpetuum Mobile, relativity principle) and measurement methodical principles we derive all fundamental equations of Mechanics. We explain the mathematical formalism from the operationalization of basic observables.

  16. Magnetism basics and applications

    CERN Document Server

    Stefanita, Carmen-Gabriela

    2012-01-01

    This textbook is aimed at engineering students who are likely to come across magnetics applications in their professional practice. Whether designing lithography equipment containing ferromagnetic brushes, or detecting defects in aeronautics, some basic knowledge of 21st century magnetism is needed. From the magnetic tape on the pocket credit card to the read head in a personal computer, people run into magnetism in many products. Furthermore, in a variety of disciplines tools of the trade exploit magnetic principles, and many interdisciplinary laboratory research areas cross paths with magnetic phenomena that may seem mysterious to the untrained mind. Therefore, this course offers a broad coverage of magnetism topics encountered more often in this millenium, revealing key concepts on which many practical applications rest. Some traditional subjects in magnetism are discussed in the first half of the book, followed by areas likely to spark the curiosity of those more interested in today’s technological achi...

  17. The chemisorptive bond basic concepts

    CERN Document Server

    Clark, Alfred

    1974-01-01

    The Chemisorptive Bond: Basic Concepts describes the basic concepts of the chemisorptive bond on solid surfaces from the simple analogies with ordinary chemical bonds to the quantum-mechanical approaches.This book is composed of 10 chapters and begins with discussions of simple formulas for correlating measurable quantities in chemisorptions and catalysis. The succeeding chapters deal with theories based on quantum-mechanical principles that describe the mutual interactions of atoms of the solid and foreign atoms on the surface. The remaining chapters consider the possible arrangements

  18. Stereochemistry basic concepts and applications

    CERN Document Server

    Nógrádi, M

    2013-01-01

    Stereochemistry: Basic Concepts and Applications is a three-chapter text that introduces the basic principles and concepts of stereochemistry, as well as its application to organic chemistry application.Chapter 1 describes first the stereochemistry of the ground state, specifically the configuration and conformation of organic compounds, as well as the most important methods for its investigation. This chapter also deals with the kinetics of conformational changes and provides an overview of the so-called ""applied stereochemistry"". Chapter 2 focuses on the analysis of the internal motions of

  19. 法律基本原则与普通公民的量刑决策--来自实验的证据%Basic Principles of Law and the Sentencing Decisions of Ordinary Citizens:The Evidence f rom the Experiment

    Institute of Scientific and Technical Information of China (English)

    李维维; 杨群; 张庆林; 曾建敏

    2014-01-01

    Presumption of innocence and the principle that all people are equal before the law are the basic principles of law which should be obeyed by judges in Chinese judicial process .To investigate whether the natural justice view of ordinary citizens is consistent with these two principles of law ,the present study employs 198 college students without professional law education or training background and asks them to make a legal decision for a suspect in an intentional homicide crime . The results show that when solid evidence is obtained ,the suspect is judged to receive much longer prison sentence than no sufficient evidence is obtained ,it means the natural justice view is consistent with the basic principles of law .When some strong but not conclusive evidence is presented ,the suspect is judged to have longer prison sentence than when no evidence is present ,w hich violates the principle of in dubio pro reo .When the suspect is the son of a government officer ,the suspect is judged to receive longer prison sentence than when the suspect is a peasant ,which violates the principle that all people are equal before the law .However ,different identities of different victims have no significant effect on sentencing .Therefore , the legal justice view of ordinary people ,which has certain subjectivity and deviation with the two basic principles of law ,is easy to be affected by emotion and moral concepts ,and represents the characteristic of bounded rationality .%无罪推定原则和法律面前人人平等是中国司法过程中审判人员需遵守的基本法律原则。为考察普通公民的自然正义观是否和这两项基本的法律原则具有一致性,本研究以198名非法学专业大学生为被试,要求被试对一桩故意杀人案的嫌疑人进行法律裁决。实验结果表明:在确证有罪的条件下,被试判决的刑期远远高于无证据的条件,表明被试的自然正义观和法律基本原则之间存在一定的一

  20. Principles of photonics

    CERN Document Server

    Liu, Jia-Ming

    2016-01-01

    With this self-contained and comprehensive text, students will gain a detailed understanding of the fundamental concepts and major principles of photonics. Assuming only a basic background in optics, readers are guided through key topics such as the nature of optical fields, the properties of optical materials, and the principles of major photonic functions regarding the generation, propagation, coupling, interference, amplification, modulation, and detection of optical waves or signals. Numerous examples and problems are provided throughout to enhance understanding, and a solutions manual containing detailed solutions and explanations is available online for instructors. This is the ideal resource for electrical engineering and physics undergraduates taking introductory, single-semester or single-quarter courses in photonics, providing them with the knowledge and skills needed to progress to more advanced courses on photonic devices, systems and applications.

  1. Principles of Mobile Communication

    CERN Document Server

    Stüber, Gordon L

    2012-01-01

    This mathematically rigorous overview of physical layer wireless communications is now in a third, fully revised and updated edition. Along with coverage of basic principles sufficient for novice students, the volume includes plenty of finer details that will satisfy the requirements of graduate students aiming to research the topic in depth. It also has a role as a handy reference for wireless engineers. The content stresses core principles that are applicable to a broad range of wireless standards. Beginning with a survey of the field that introduces an array of issues relevant to wireless communications and which traces the historical development of today’s accepted wireless standards, the book moves on to cover all the relevant discrete subjects, from radio propagation to error probability performance and cellular radio resource management. A valuable appendix provides a succinct and focused tutorial on probability and random processes, concepts widely used throughout the book. This new edition, revised...

  2. Procedure system principles

    International Nuclear Information System (INIS)

    Procedures establish how an organization performs specific tasks to accomplish its basic goals and objectives. In 1990, the US Department of Energy (DOE) started the process of defining requirements to be used for procedures throughout the DOE nuclear complex. In response to the customer needs of the complex, the department's initial steps in this process were to develop two documents: a writer's guide for technical procedures and the principles of procedure writing upon which it was based. The US Nuclear Regulatory Commission and Institute for Nuclear Power Operations literature addresses the control and use of procedures. There was, however, no regulatory guidance on developing and managing a procedure system. In 1991, an effort was undertaken to provide such guidance for DOE nuclear facilities. A companion paper by Grider and Plung describes how a performance-tested advisory group developed this guidance. This paper describes the procedure system principles that were developed through this process

  3. Uncertainty Principle Respects Locality

    CERN Document Server

    Wang, Dongsheng

    2013-01-01

    The notion of nonlocality implicitly implies there might be some kind of spooky action at a distance in nature, however, the validity of quantum mechanics has been well tested up to now. In this work it is argued that the notion of nonlocality is physically improper, the basic principle of locality in nature is well respected by quantum mechanics, namely, the uncertainty principle. We show that the quantum bound on the Clauser, Horne, Shimony, and Holt (CHSH) inequality can be recovered from the uncertainty relation in a multipartite setting, and the same bound exists classically which indicates that nonlocality does not capture the essence of quantum and then distinguish quantum mechanics and classical mechanics properly. We further argue that the super-quantum correlation demonstrated by the nonlocal box is not physically comparable with the quantum one, as the result, the physical foundation for the existence of nonlocality is falsified. The origin of the quantum structure of nature still remains to be exp...

  4. Principles of systems science

    CERN Document Server

    Mobus, George E

    2015-01-01

    This pioneering text provides a comprehensive introduction to systems structure, function, and modeling as applied in all fields of science and engineering. Systems understanding is increasingly recognized as a key to a more holistic education and greater problem solving skills, and is also reflected in the trend toward interdisciplinary approaches to research on complex phenomena. The subject of systems science, as a basis for understanding the components and drivers of phenomena at all scales, should be viewed with the same importance as a traditional liberal arts education. Principles of Systems Science contains many graphs, illustrations, side bars, examples, and problems to enhance understanding. From basic principles of organization, complexity, abstract representations, and behavior (dynamics) to deeper aspects such as the relations between information, knowledge, computation, and system control, to higher order aspects such as auto-organization, emergence and evolution, the book provides an integrated...

  5. Principles of fluorescence techniques

    CERN Document Server

    2016-01-01

    Fluorescence techniques are being used and applied increasingly in academics and industry. The Principles of Fluorescence Techniques course will outline the basic concepts of fluorescence techniques and the successful utilization of the currently available commercial instrumentation. The course is designed for students who utilize fluorescence techniques and instrumentation and for researchers and industrial scientists who wish to deepen their knowledge of fluorescence applications. Key scientists in the field will deliver theoretical lectures. The lectures will be complemented by the direct utilization of steady-state and lifetime fluorescence instrumentation and confocal microscopy for FLIM and FRET applications provided by leading companies.

  6. Principles of speech coding

    CERN Document Server

    Ogunfunmi, Tokunbo

    2010-01-01

    It is becoming increasingly apparent that all forms of communication-including voice-will be transmitted through packet-switched networks based on the Internet Protocol (IP). Therefore, the design of modern devices that rely on speech interfaces, such as cell phones and PDAs, requires a complete and up-to-date understanding of the basics of speech coding. Outlines key signal processing algorithms used to mitigate impairments to speech quality in VoIP networksOffering a detailed yet easily accessible introduction to the field, Principles of Speech Coding provides an in-depth examination of the

  7. Principles of quantum chemistry

    CERN Document Server

    George, David V

    2013-01-01

    Principles of Quantum Chemistry focuses on the application of quantum mechanics in physical models and experiments of chemical systems.This book describes chemical bonding and its two specific problems - bonding in complexes and in conjugated organic molecules. The very basic theory of spectroscopy is also considered. Other topics include the early development of quantum theory; particle-in-a-box; general formulation of the theory of quantum mechanics; and treatment of angular momentum in quantum mechanics. The examples of solutions of Schroedinger equations; approximation methods in quantum c

  8. [Physiological behavior of Cantilever].

    Science.gov (United States)

    Feeldman, I; Frugone, R; Vládilo, N T

    1990-11-01

    The prosthetic rehabilitation is common of the integral treatment of patients that integral treatment of patients that have lost one or several dental pieces as a consequence of periodontal diseases. It has been demonstrated that plural fixed prothesis to extention, plovide a distribution pattern and magnitude of favourable forces to the periodontal during the different functions of the stomathologic apparatus, that justify rehabilitation based to it patients periodontically affected. The physiological behaviour of cantilever was basically analized on report on different investigation studies performed on patients periodontically diminis hed treated with plural fixed prothesis of crossed are with two unit or bilateral vear cantilever units, dento supported or fixed in place on implants. It is important to emphasize that favourable results previously analized in base to this type of rehabilitation in its different varieties have been obtained through record done on patients in which considerations of indications, design and occlusion stability have been optimized. PMID:2075270

  9. Echocardiographic assessment of pressure volume relations in heart failure and valvular heart disease: using imaging to understand physiology

    Science.gov (United States)

    Green, P.; Kodali, S.; Leon, M. B.; Maurer, M. S.

    2016-01-01

    Pressure volume (PV) based analysis, using classic hemodynamic principles, has served as a basis for our understanding of cardiac physiology and disease states for decades. However, PV analysis has been restricted to primarily the basic research setting and for preclinical testing and has not be widely applied in part because of the invasive nature of the procedure and the expertise required to obtain adequate data using the conductance catheter. Development of single beat methodologies that rely on echocardiographic measurements of ventricular volume and Doppler and peripheral estimates of ventricular pressure and timing of the cardiac cycle has enabled broader application of PV analysis. This review explores the physiologic background, basic methodology, and recent and potential future applications of noninvasive PV analysis. PMID:21705998

  10. The Oscillator Principle of Nature

    DEFF Research Database (Denmark)

    Lindberg, Erik

    2012-01-01

    Oscillators are found on all levels in Nature. The general oscillator concept is defined and investigated. Oscillators may synchronize into fractal patterns. Apparently oscillators are the basic principle in Nature. The concepts of zero and infinite are discussed. Electronic manmade oscillators are...

  11. Physiological homology between Drosophila melanogaster and vertebrate cardiovascular systems

    OpenAIRE

    Choma, Michael A.; Suter, Melissa J.; Vakoc, Benjamin J.; Bouma, Brett E; Tearney, Guillermo J.

    2010-01-01

    SUMMARY The physiology of the Drosophila melanogaster cardiovascular system remains poorly characterized compared with its vertebrate counterparts. Basic measures of physiological performance remain unknown. It also is unclear whether subtle physiological defects observed in the human cardiovascular system can be reproduced in D. melanogaster. Here we characterize the cardiovascular physiology of D. melanogaster in its pre-pupal stage by using high-speed dye angiography and optical coherence ...

  12. XAFS Spectroscopy : Fundamental Principles and Data Analysis

    NARCIS (Netherlands)

    Koningsberger, D.C.; Mojet, B.L.; Dorssen, G.E. van; Ramaker, D.E.

    2000-01-01

    The physical principles of XAFS spectroscopy are given at a sufficiently basic level to enable scientists working in the field of catalysis to critically evaluate articles dealing with XAFS studies on catalytic materials. The described data-analysis methods provide the basic tools for studying the e

  13. Skin physiology and textiles - consideration of basic interactions.

    Science.gov (United States)

    Wollina, U; Abdel-Naser, M B; Verma, S

    2006-01-01

    The skin exerts a number of essential protective functions ensuring homeostasis of the whole body. In the present review barrier function of the skin, thermoregulation, antimicrobial defence and the skin-associated immune system are discussed. Barrier function is provided by the dynamic stratum corneum structure composed of lipids and corneocytes. The stratum corneum is a conditio sine qua non for terrestrial life. Impairment of barrier function can be due to injury and inflammatory skin diseases. Textiles, in particular clothing, interact with skin functions in a dynamic pattern. Mechanical properties like roughness of fabric surface are responsible for non-specific skin reactions like wool intolerance or keratosis follicularis. Thermoregulation, which is mediated by local blood flow and evaporation of sweat, is an important subject for textile-skin interactions. There are age-, gender- and activity-related differences in thermoregulation of skin that should be considered for the development of specifically designed fabrics. The skin is an important immune organ with non-specific and specific activities. Antimicrobial textiles may interfere with non-specific defence mechanisms like antimicrobial peptides of skin or the resident microflora. The use of antibacterial compounds like silver, copper or triclosan is a matter of debate despite their use for a very long period. Macromolecules with antimicrobial activity like chitosan that can be incorporated into textiles or inert material like carbon fibres or activated charcoal seem to be promising agents. Interaction of textiles with the specific immune system of skin is a rare event but may lead to allergic contact dermatitis. Electronic textiles and other smart textiles offer new areas of usage in health care and risk management but bear their own risks for allergies. PMID:16766877

  14. Physiological, Psychological, and Social Effects of Noise

    Science.gov (United States)

    Kryter, K. D.

    1984-01-01

    The physiological, and behavioral effects of noise on man are investigated. Basic parameters such as definitions of noise, measuring techniques of noise, and the physiology of the ear are presented prior to the development of topics on hearing loss, speech communication in noise, social effects of noise, and the health effects of noise pollution. Recommendations for the assessment and subsequent control of noise is included.

  15. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available Experts \\ The Basics of Spinal Cord Injury Rehabilitation Topics Adult Injuries Spinal Cord Injury 101 Spinal Cord Injury 101 The Basics of Spinal Cord Injury Rehabilitation The Basics ...

  16. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available Experts \\ The Basics of Spinal Cord Injury Rehabilitation Topics Adult Injuries Spinal Cord Injury 101 Spinal Cord Injury 101 The Basics of Spinal Cord Injury Rehabilitation The Basics of Spinal Cord ...

  17. Stem Cell Basics

    Science.gov (United States)

    ... Information Stem Cell Basics Stem Cell Basics: Introduction Stem Cell Information General Information Clinical Trials Funding Information Current Research Policy Glossary Site Map Stem Cell Basics Introduction: What are stem cells, and why ...

  18. Basics of SCI Rehabilitation

    Science.gov (United States)

    Experts \\ The Basics of Spinal Cord Injury Rehabilitation Topics Adult Injuries Spinal Cord Injury 101 Spinal Cord Injury 101 The Basics of Spinal Cord Injury Rehabilitation The Basics of Spinal Cord ...

  19. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available Experts \\ The Basics of Spinal Cord Injury Rehabilitation Topics Adult Injuries Spinal Cord Injury 101 Spinal Cord Injury 101 The Basics of Spinal Cord Injury Rehabilitation The Basics of ...

  20. Principles of Bioremediation Assessment

    Science.gov (United States)

    Madsen, E. L.

    2001-12-01

    Although microorganisms have successfully and spontaneously maintained the biosphere since its inception, industrialized societies now produce undesirable chemical compounds at rates that outpace naturally occurring microbial detoxification processes. This presentation provides an overview of both the complexities of contaminated sites and methodological limitations in environmental microbiology that impede the documentation of biodegradation processes in the field. An essential step toward attaining reliable bioremediation technologies is the development of criteria which prove that microorganisms in contaminated field sites are truly active in metabolizing contaminants of interest. These criteria, which rely upon genetic, biochemical, physiological, and ecological principles and apply to both in situ and ex situ bioremediation strategies include: (i) internal conservative tracers; (ii) added conservative tracers; (iii) added radioactive tracers; (iv) added isotopic tracers; (v) stable isotopic fractionation patterns; (vi) detection of intermediary metabolites; (vii) replicated field plots; (viii) microbial metabolic adaptation; (ix) molecular biological indicators; (x) gradients of coreactants and/or products; (xi) in situ rates of respiration; (xii) mass balances of contaminants, coreactants, and products; and (xiii) computer modeling that incorporates transport and reactive stoichiometries of electron donors and acceptors. The ideal goal is achieving a quantitative understanding of the geochemistry, hydrogeology, and physiology of complex real-world systems.

  1. Physiological effects in aromatherapy

    OpenAIRE

    Tapanee Hongratanaworakit

    2004-01-01

    The effects of aromas on humans are divided into physiological and psychological effects. The physiological effect acts directly on the physical organism, the psychological effect acts via the sense of smell or olfactory system, which in turn may cause a physiological effect. This paper reviews on the physiological effects which are used for the evaluation of the effects of aromas. Physiological parameters, i.e. heart rate blood pressure, electrodermal activity, electroencephalogram, slow pot...

  2. Basic neutronics. Neutrons migration

    International Nuclear Information System (INIS)

    This article presents the basic neutronics necessary for the understanding of the operation of the different types of nuclear reactors: 1 - introduction to neutronics: principle of fission chain reactions, fast neutron reactors and thermal neutron reactors, capture, neutron status, variations with the reactor lattices; 2 - Boltzmann equation: neutrons population, neutrons migration, characterization of neutrons population and reactions, integral form of the Boltzmann equation, integral-differential form, equivalence between the two forms; 3 - reactor kinetics: fast neutrons and delayed neutrons, kinetic equations in punctual model, Nordheim equation, reactivity jumps, reactivity ramp; 4 - diffusion equation: local neutron status, Fick's law, diffusion equation, initial, boundary and interface conditions, nuclei in infinite and homogenous medium, some examples of solutions, developments in Eigenmodes; 5 - one-group theory: equation of the 'one-group - diffusion' theory, critical condition of the naked and homogenous reactor, critical condition of a reactor with reflectors, generalizations; 6 - neutrons moderation: different moderation mechanisms, elastic shock laws, moderation equation, some examples of solutions; 7 - resonance absorption of neutrons: advantage of the discontinuous moderation character, advantage of an heterogenous disposition, classical formula of the anti-trap factor in homogenous and heterogenous situation; 8 - neutrons thermalization: notions of thermalization mechanisms, thermalization equation, Maxwell spectrum, real spectrum, classical formula of the thermal utilisation factor, classical formula of the reproduction factor, moderation optimum. (J.S.)

  3. Basic operator theory

    CERN Document Server

    Gohberg, Israel

    2001-01-01

    rii application of linear operators on a Hilbert space. We begin with a chapter on the geometry of Hilbert space and then proceed to the spectral theory of compact self adjoint operators; operational calculus is next presented as a nat­ ural outgrowth of the spectral theory. The second part of the text concentrates on Banach spaces and linear operators acting on these spaces. It includes, for example, the three 'basic principles of linear analysis and the Riesz­ Fredholm theory of compact operators. Both parts contain plenty of applications. All chapters deal exclusively with linear problems, except for the last chapter which is an introduction to the theory of nonlinear operators. In addition to the standard topics in functional anal­ ysis, we have presented relatively recent results which appear, for example, in Chapter VII. In general, in writ­ ing this book, the authors were strongly influenced by re­ cent developments in operator theory which affected the choice of topics, proofs and exercises. One ...

  4. Ecological principles relevant to nuclear war

    International Nuclear Information System (INIS)

    The ecological principles outlined are very basic ones; the authors anticipate a readership trained in a broad range of disciplines, including those unfamiliar with the academic discipline of ecology. The authors include substantial discussion on ecophysiology (i.e., the responses of organisms to their environment) because this is relevant to the new understanding of the potential climatic consequences of nuclear war. In particular, the physiological sensitivity of organisms to reduced levels of light and temperature are a key part of the analysis of the potential ecological effects and agricultural effects of nuclear war. Much of the ecological analysis has been organized around major biological units called biomes. The authors describe the biome concept and discuss some of the environmental-climatic factors that are believed to control biome distribution. Emphasis is given to plants because of their controlling influence on ecosystem functions through their role as primary producers. Future reports are needed to address more fully the potential effects on animals. Much more research needs to be done on both plant and animal responses to the types of perturbations possible for the aftermath of a nuclear war. Another important element for analysis of the potential ecological consequences of nuclear war concerns recovery processes. As the post-nuclear war environmental extremes ameliorate, ecological communities in devastated regions would begin to reorganize. It is not possible to predict the course of such a succession precisely, but some principles concerning post-perturbation replacement (such as seed banks and germination), relevant successional patterns, and organism strategies are discussed

  5. Physiology in Modelica

    Directory of Open Access Journals (Sweden)

    Marek Mateják

    2014-05-01

    Full Text Available Modelica is an object-oriented language, in which models can be created and graphically represented by connecting instances of classes from libraries. These connections are not only assignments of values; they can also represent acausal equality. Even more, they can model Kirchhoff’s laws of circuits. In Modelica it is possible to develop library classes which are an analogy of electrical circuit components. The result of our work in this field is Physiolibrary (www.physiolibrary.org – a free, open-source Modelica library for human physiology. By graphical joining instances of Physiolibrary classes, user can create models of cardiovascular circulation, thermoregulation, metabolic processes, nutrient distribution, gas transport, electrolyte regulation, water distribution, hormonal regulation and pharmacological regulation. After simple setting of the parameters, the models are ready to simulate. After simulation, the user can examine variables as their values change over time. Representing the model as a diagram has also great educational advantages, because students are able to better understand physical principles when they see them modeled graphically.

  6. Lung physiology and anatomy

    International Nuclear Information System (INIS)

    This paper discusses the factors influencing respiration and presents the physiological principles that provide the basis for pulmonary function measurements and for the procedures used in pulmonary nuclear medicine. Respiration is defined as the consumption of O/sub 2/ and the production of CO/sub 2/ at the cellular level, and by extension in common usage the term refers to the entire process leading to gas exchange between the body and the environment. Gas exchange in man can be divided into three principal, but interdependent, functional components: (1) that concerned with the volume and and distribution of air flow within the lungs; (2) that concerned with the volume and distribution of blood flow through the pulmonary circulation; and (3) that concerned with the diffusion of O/sub 2/ and CO/sub 2/ across the air-blood barrier. The air-blood barrier in the terminal respiratory units is the site at which inspired fresh air (ventilation) is brought into contact with the film of blood flowing through the pulmonary capillaries (perfusion)

  7. Some Basic Techniques in Bioimpedance Research

    Science.gov (United States)

    Martinsen, Ørjan G.

    2004-09-01

    Any physiological or anatomical changes in a biological material will also change its electrical properties. Hence, bioimpedance measurements can be used for diagnosing or classification of tissue. Applications are numerous within medicine, biology, cosmetics, food industry, sports, etc, and different basic approaches for the development of bioimpedance techniques are discussed in this paper.

  8. Principles of modern physics

    CERN Document Server

    Saxena, A K

    2014-01-01

    Principles of Modern Physics, divided into twenty one chapters, begins with quantum ideas followed by discussions on special relativity, atomic structure, basic quantum mechanics, hydrogen atom (and Schrodinger equation) and periodic table, the three statistical distributions, X-rays, physics of solids, imperfections in crystals, magnetic properties of materials, superconductivity, Zeeman-, Stark- and Paschen Back- effects, Lasers, Nuclear physics (Yukawa's meson theory and various nuclear models), radioactivity and nuclear reactions, nuclear fission, fusion and plasma, particle accelerators and detectors, the universe, Elementary particles (classification, eight fold way and quark model, standard model and fundamental interactions), cosmic rays, deuteron problem in nuclear physics, and cathode ray oscilloscope. NEW TO THE FOURTH EDITION: The CO2 Laser Theory of magnetic moments on the basis of shell model Geological dating Laser Induced fusion and laser fusion reactor. Hawking radiation The cosmological red ...

  9. Kepler and Mach's Principle

    Science.gov (United States)

    Barbour, Julian

    The definitive ideas that led to the creation of general relativity crystallized in Einstein's thinking during 1912 while he was in Prague. At the centenary meeting held there to mark the breakthrough, I was asked to talk about earlier great work of relevance to dynamics done at Prague, above all by Kepler and Mach. The main topics covered in this chapter are: some little known but basic facts about the planetary motions; the conceptual framework and most important discoveries of Ptolemy and Copernicus; the complete change of concepts that Kepler introduced and their role in his discoveries; the significance of them in Newton's work; Mach's realization that Kepler's conceptual revolution needed further development to free Newton's conceptual world of the last vestiges of the purely geometrical Ptolemaic world view; and the precise formulation of Mach's principle required to place GR correctly in the line of conceptual and technical evolution that began with the ancient Greek astronomers.

  10. Basic constant of matter world

    International Nuclear Information System (INIS)

    It was analysed how to gain constant 46 hidden among elementary units of matter world, which is divided into, 1, 2, 4, 8, 16, 8, 4, 2, 1. Here it shows the unity of opposites on philosophy and simple symmetric beauty of mathphysics. The constant specifically shows that scope constant 44 in nuclides layer of matter world and chromosome number of mankind is 23 pairs, which is the highest form of matter motion, the basic cause of existing constant 46 is that matter exists in space-time with 4-dimensions, and it obeys the principle of the most lower energy

  11. Health insurance basic actuarial models

    CERN Document Server

    Pitacco, Ermanno

    2014-01-01

    Health Insurance aims at filling a gap in actuarial literature, attempting to solve the frequent misunderstanding in regards to both the purpose and the contents of health insurance products (and ‘protection products’, more generally) on the one hand, and the relevant actuarial structures on the other. In order to cover the basic principles regarding health insurance techniques, the first few chapters in this book are mainly devoted to the need for health insurance and a description of insurance products in this area (sickness insurance, accident insurance, critical illness covers, income protection, long-term care insurance, health-related benefits as riders to life insurance policies). An introduction to general actuarial and risk-management issues follows. Basic actuarial models are presented for sickness insurance and income protection (i.e. disability annuities). Several numerical examples help the reader understand the main features of pricing and reserving in the health insurance area. A short int...

  12. Magnetic resonance imaging the basics

    CERN Document Server

    Constantinides, Christakis

    2014-01-01

    Magnetic resonance imaging (MRI) is a rapidly developing field in basic applied science and clinical practice. Research efforts in this area have already been recognized with five Nobel prizes awarded to seven Nobel laureates in the past 70 years. Based on courses taught at The Johns Hopkins University, Magnetic Resonance Imaging: The Basics provides a solid introduction to this powerful technology. The book begins with a general description of the phenomenon of magnetic resonance and a brief summary of Fourier transformations in two dimensions. It examines the fundamental principles of physics for nuclear magnetic resonance (NMR) signal formation and image construction and provides a detailed explanation of the mathematical formulation of MRI. Numerous image quantitative indices are discussed, including (among others) signal, noise, signal-to-noise, contrast, and resolution. The second part of the book examines the hardware and electronics of an MRI scanner and the typical measurements and simulations of m...

  13. Basic principles set out in the Codex Alimentarius

    International Nuclear Information System (INIS)

    The power point presentation is about food innocuousness, toxicology , nutrition, incertitude, availability data and interpretation, certitude grade, when evaluate the risk, danger identification, exposition population, qualitative probability and estimation, cuantitative risk, exposure limits, methods, methods based on the concept of threshold, general equation

  14. Heisenberg uncertainty principle and economic analogues of basic physical quantities

    CERN Document Server

    Soloviev, Vladimir

    2011-01-01

    From positions, attained by modern theoretical physics in understanding of the universe bases, the methodological and philosophical analysis of fundamental physical concepts and their formal and informal connections with the real economic measurings is carried out. Procedures for heterogeneous economic time determination, normalized economic coordinates and economic mass are offered, based on the analysis of time series, the concept of economic Plank's constant has been proposed. The theory has been approved on the real economic dynamic's time series, including stock indices, Forex and spot prices, the achieved results are open for discussion.

  15. Basic HR Risk Management Principles in Digital Libraries

    OpenAIRE

    Mirembe, Florence

    2009-01-01

    Human beings are responsible for causing risk as well as mitigating risk. This paper focuses on the human resources management risk remedies for digital libraries. Risk management aims at identifying, assessing and resolving risk items before they become disasters to an organization or digital library. Effective risk management plans should include short-term and long-term risks to project schedules, costs, and the functionality, adequacy and quality of project deliverables. Risks can bec...

  16. Resonant X-ray diffraction: Basic theoretical principles

    International Nuclear Information System (INIS)

    We present the main steps governing the theory of resonant X-ray diffraction (RXD). We focus on the derivation of the anomalous scattering amplitude from perturbation theory and starting from the low-energy expansion of the Dirac Hamiltonian. We give the main ingredients of the multipolar expansion in term of electric and magnetic transitions. We also show the expansion in terms of scattering tensors of the material. We end by giving the RXD formula necessary to simulate in practice this spectroscopy. (authors)

  17. Many-particle quantum hydrodynamics: Basic principles and fundamental applications

    CERN Document Server

    Andreev, P A

    2014-01-01

    We present a detailed derivation of the continuity, Euler, and energy balance equations from many particle Schrodinger equation. Interparticle interaction is explicitly considered as the Coulomb interaction. We show the QHD equations in a form suitable for low dimensional systems. The QHD equations in the cylindrical and spherical coordinates are presented as well. We present a method of non-linear Schrodinger equation derivation from the QHD equations. We describe a method of exchange interaction calculation for two- and three-dimensional quantum plasmas. We discuss explicit form and area of applicability of equations of state for 1D, 2D, and 3D degenerate electrons. We explicitly consider equations of state for degenerate electron gas in an external magnetic field. Considering QHD equations in cylindrical coordinates we focus our attention on the quantum part of the inertia forces and contribution of the quantum Bohm potential to the spectrum of quantum cylindrical waves. Collective excitations of 2DEG on s...

  18. The notion and basic principles of restorative justice

    OpenAIRE

    Ćopić Sanja

    2007-01-01

    One of the most important achievements of the contemporary criminal justice system and criminal policy is development of the concept of restorative justice. Contemporary concept of restorative justice was developed in 1970s on the basis of the criticism of the traditional criminal law and criminal justice system. Since that time, it has been developing through different programs in many countries. Reform of the criminal justice system in Serbia staring from 2002 went into direction of enterin...

  19. Basic principles and stages of differential radiodiagnosis in emergency gastroenterology

    International Nuclear Information System (INIS)

    Diagnostic tactics of radiographic examination of patients with diseases and injuries of digestive tract depends on peculiarities of clinical picture and preliminary diagnosis of the disease. When there are signs of perforated injury of the wall of a hollow organ radiographic examination using ultrasonic study is recommended for pneumoperitoneum diagnosis. Computer tomography is a highly efficient method in diagnosis of acute intestinal obstruction. Malfunctioning of parenchymatous organs in case of closed injury of abdomen are clearly recognized using computer tomography. The method of scintigraphy with 99mTc labelled erythrocytes is employed to ascertain the level of hemorrhage to gastroenteric tract

  20. [Sleep disorders: principles, basic diagnostics and elementary measures and recommendations].

    Science.gov (United States)

    Gerlach, Martin; Sanner, Bernd

    2015-08-01

    Sleep disorders are frequent. Economic costs and impairment of quality of life can be substantial. Usually, patients suffer from insomnia or hypersomnia. Several effective therapeutic options are available. Sleep disorders appear independently or accompany a multitude of organic and psychiatric diseases. Fatigue has to be distinguished from sleep disorders clearly. For classification, the ICSD-3, published by the American Academy of Sleep Medicine, is used. Patients should be explicitly asked for their sleep quality, for many do not report actively. Patient's history and clinical examination usually narrow the diagnosis to a large extent. Clinical diagnostics should be carried out according to the diagnostic algorithm by the German Sleep Society (DGSM). An optimal sleep hygiene and if necessary weight reduction are crucial and can prevent chronification and health consequences. In addition, assistive technology, drug therapy, behaviour therapy, and in few cases surgery are available. PMID:26306014

  1. Radiology Information Systems: Basic Principles and Current Practice

    OpenAIRE

    Lehr, James L.

    1981-01-01

    Because radiology represents a sizeable financial and operational component of any health care delivery system, the needs for and opportunities provided by a radiology information system should be carefully considered in planning any medical data processing system. Experience with such systems over the past fifteen years has demonstrated that they can improve service quality and save money. The functions which can be performed by radiology computer systems are relatively well defined and will...

  2. Thymic epithelial tumours: from basic principles to individualised treatment strategies

    Directory of Open Access Journals (Sweden)

    Nicolas Girard

    2013-03-01

    Full Text Available Thymic epithelial tumours represent a wide range of anatomical, clinical, histological and molecular malignant entities that may be aggressive and difficult to treat. The histopathological classification distinguishes thymomas from thymic carcinomas. Thymomas may be associated with autoimmune disorders. The management of thymic epithelial tumours is a paradigm of co-operation between clinicians, surgeons and pathologists, from establishing the diagnosis to organising the multimodal therapeutic strategy. Surgery is the mainstay of the curative-intent treatment, as complete resection represents the most significantly favourable prognostic factor on overall survival. In case of invasion of intra-thoracic structures and/or dissemination to the pleura and the pericardium, precluding complete resection to be achieved, primary chemotherapy has been used to reduce the tumour burden, possibly allowing subsequent surgery and/or radiotherapy. Novel strategies are needed, especially for refractory, recurrent tumours and thymic carcinomas, which carry a poor prognosis. Personalised approaches are currently being developed, as potentially “druggable” molecular targets are emerging from recent integrated genomic analyses. Along with the large variety of questions relative to the treatment strategy, thymic epithelial tumours represent a model of therapeutic implementation and achievement in orphan thoracic oncology, showing how the advent of new results induces new questions, as well as diversifies further clinical research directions and international collaborative initiatives.

  3. Radiofrequency Ablation of Thyroid Nodules: Basic Principles and Clinical Application

    OpenAIRE

    Ji Hoon Shin; Jung Hwan Baek; Eun Ju Ha; Jeong Hyun Lee

    2012-01-01

    Radiofrequency (RF) ablation has been gaining popularity as a minimally invasive treatment for benign thyroid nodules regardless of the extent of the solid component. RF ablation of benign nodules demonstrated volume reductions of 33–58% after one month and 51–85% after six months, while solving nodule-related clinical problems. RF ablation has recently shown positive short-term results for locoregional control as well as symptom improvement in patients with recurrent thyroid cancers. This pa...

  4. Heisenberg uncertainty principle and economic analogues of basic physical quantities

    OpenAIRE

    Vladimir Soloviev; Vladimir Saptsin

    2011-01-01

    From positions, attained by modern theoretical physics in understanding of the universe bases, the methodological and philosophical analysis of fundamental physical concepts and their formal and informal connections with the real economic measurings is carried out. Procedures for heterogeneous economic time determination, normalized economic coordinates and economic mass are offered, based on the analysis of time series, the concept of economic Plank's constant has been proposed. The theory h...

  5. Introduction on PET : Description of Basics and Principles

    NARCIS (Netherlands)

    van Waarde, Aren; Elsinga, Philip H; van Waarde, Aren; Paans, Anne MJ; Dierckx, Rudi AJO

    2012-01-01

    Positron emission tomography (or PET) is a non-destructive imaging technique in nuclear medicine with several unique properties: high sensitivity, low radiation dose, possibility to correct data for attenuation and scatter (thus quantitative), radioactive labeling of natural substances or drugs with

  6. Coatings in Dentistry—A Review of Some Basic Principles

    OpenAIRE

    Karl-Johan M. Söderholm

    2012-01-01

    Different coatings are used in dentistry in an attempt to prevent caries, improve bonding of restorative materials to tooth tissues, and coat implant surfaces in efforts to speed up osseointegration. These are just a few of the many coating applications used in dentistry. The intention of this review is not to cover the entire field of different coatings used in dentistry, because that topic is just too big to be covered in one single paper. Therefore, this review aims to highlight some funda...

  7. Ozone in the atmosphere. Basic principles, natural and human impacts

    Energy Technology Data Exchange (ETDEWEB)

    Fabian, Peter [Technical Univ. Munich (Germany). Immission Research; Dameris, Martin [German Aerospace Center (DLR), Oberpfaffenhofen-Wessling (Germany). Inst. of Atmospheric Physics

    2014-09-01

    Comprehensive coverage of ozone both in the upper and the lower atmosphere. Essential overview of atmospheric ozone research written by two experienced and acknowledged experts. Numerous qualified references to the scientific literature. Peter Fabian and Martin Dameris provide a concise yet comprehensive overview of established scientific knowledge about ozone in the atmosphere. They present both ozone changes and trends in the stratosphere, as well as the effects of overabundance in the troposphere including the phenomenon of photosmog. Aspects such as photochemistry, atmospheric dynamics and global ozone distribution as well as various techniques for ozone measurement are treated. The authors outline the various causes for ozone depletion, the effects of ozone pollution and the relation to climate change. The book provides a handy reference guide for researchers active in atmospheric ozone research and a useful introduction for advanced students specializing in this field. Non-specialists interested in this field will also profit from reading the book. Peter Fabian can look back on a life-long active career in ozone research, having first gained international recognition for his measurements of the global distribution of halogenated hydrocarbons. He also pioneered photosmog investigations in the metropolitan areas of Munich, Berlin, Athens and Santiago de Chile, and his KROFEX facility provided controlled ozone fumigation of adult tree canopies for biologists to investigate the effects of ozone increases on forests. Besides having published a broad range of scientific articles, he has also been the author or editor of numerous books. From 2002 to 2005 he served the European Geosciences Union (EGU) as their first and Founding President. Martin Dameris is a prominent atmospheric modeler whose interests include the impacts of all kinds of natural and man-made disturbances on the atmospheric system. His scientific work focuses on the connections between ozone and climate changes. For many years he has been an active contributor to the WMO scientific ozone depletion assessments, which have been used to monitor the depletion and recovery of the ozone layer in accordance with the Montreal Protocol.

  8. Basic principles and mechanisms of selective oil agglomeration

    Energy Technology Data Exchange (ETDEWEB)

    Wheelock, T.D.; Drzymala, J.; Allen, R.W.; Hu, Y.-C.; Tyson, D.; Xiaoping, Qiu; Lessa, A.

    1990-01-01

    Numerous measurements of the heat of immersion of coal were conducting using several different particle size fractions of No. 2 Gas Seam coal from Raleigh County, West Virginia. The heat of immersion was determined in water, methanol, heptane, hexadecane and neohexane (2,2-dimethybutane). A comparison of the results with those determined previously for Illinois No. 6 coal is discussed. A number of potential pyrite depressants for use in oil agglomeration of coal were screened by testing the response of sulfidized mineral pyrite to agglomeration with heptane in the presence of the potential depressant. The following were tested; sodium dithionite, sodium thiosulfate, ferrous sulfate, ferric sulfate, titanous chloride, hydrogen peroxide, Oxone (a form of potassium monopersulfate), pyrogallol, quebracho (colloidal dispersant derived from tree bark), milk whey, and several organic thiols. Ferric chloride was applied to mixtures of Upper Freeport coal and sulfidized mineral pyrite before subjecting the mixtures to agglomeration with heptane. 7 refs., 23 figs., 3 tabs.

  9. Ozone in the atmosphere. Basic principles, natural and human impacts

    International Nuclear Information System (INIS)

    Comprehensive coverage of ozone both in the upper and the lower atmosphere. Essential overview of atmospheric ozone research written by two experienced and acknowledged experts. Numerous qualified references to the scientific literature. Peter Fabian and Martin Dameris provide a concise yet comprehensive overview of established scientific knowledge about ozone in the atmosphere. They present both ozone changes and trends in the stratosphere, as well as the effects of overabundance in the troposphere including the phenomenon of photosmog. Aspects such as photochemistry, atmospheric dynamics and global ozone distribution as well as various techniques for ozone measurement are treated. The authors outline the various causes for ozone depletion, the effects of ozone pollution and the relation to climate change. The book provides a handy reference guide for researchers active in atmospheric ozone research and a useful introduction for advanced students specializing in this field. Non-specialists interested in this field will also profit from reading the book. Peter Fabian can look back on a life-long active career in ozone research, having first gained international recognition for his measurements of the global distribution of halogenated hydrocarbons. He also pioneered photosmog investigations in the metropolitan areas of Munich, Berlin, Athens and Santiago de Chile, and his KROFEX facility provided controlled ozone fumigation of adult tree canopies for biologists to investigate the effects of ozone increases on forests. Besides having published a broad range of scientific articles, he has also been the author or editor of numerous books. From 2002 to 2005 he served the European Geosciences Union (EGU) as their first and Founding President. Martin Dameris is a prominent atmospheric modeler whose interests include the impacts of all kinds of natural and man-made disturbances on the atmospheric system. His scientific work focuses on the connections between ozone and climate changes. For many years he has been an active contributor to the WMO scientific ozone depletion assessments, which have been used to monitor the depletion and recovery of the ozone layer in accordance with the Montreal Protocol.

  10. Conflict at work: Basic principles and applied issues

    NARCIS (Netherlands)

    C.K.W. de Dreu

    2011-01-01

    Conflict at work is quickly classified as a "darkside" construct that has primarily negative, destructive, and aversive consequences to individual employees’ well-being and task performance, to citizenship behavior and performance in work teams, and to organizational fitness and survival chances. In

  11. Basic principles of magnetic resonance imaging - an update

    Energy Technology Data Exchange (ETDEWEB)

    Scherzinger, A.L.; Hendee, W.R.

    1985-12-01

    Magnetic resonance (MR) imaging technology has undergone many technologic advances over the past few years. Many of these advances were stimulated by the wealth of information emerging from nuclear magnetic resonance research in the areas of new and optimal scanning methods and radio-frequency coil design. Other changes arose from the desire to improve image quality, ease siting restrictions and generally facilitate the clinical use of MR equipment. Many questions, however, remain unanswered. Perhaps the most controversial technologic question involves the optimal field strength required for imaging or spectroscopic applications or both. Other issues include safety and clinical efficacy. Technologic issues affect all aspects of MR use including the choice of equipment, examination procedure and image interpretation. Thus, an understanding of recent changes and their theoretic basis is necessary. 92 references, 10 figures, 1 table.

  12. Current knowledge on the basic principles of concrete shrinkage

    Directory of Open Access Journals (Sweden)

    Aroni, S.

    1966-12-01

    Full Text Available Not availableLa retracción es, con frecuencia, responsable del agrietamiento del hormigón. Este trabajo resume el estado actual de conocimientos en cuanto a los principios que gobiernan el fenómeno de retracción en el hormigón. La tobermorita es el producto principal de los cementos portland hidratados y es, generalmente, la mayor fuente de retracción por secado en el cemento endurecido. Consecuentemente, la explicación de la retracción por secado se basa en la estructura cristalográfica de la tobermorita, en la naturaleza del agua asociada con ella y en los cambios de volumen que corresponden con los cambios de agua asociada. También se discute brevemente la influencia de otros factores, tales como la composición del cemento, el contenido de árido, la proporción de mezcla y las condiciones de curado.

  13. Basic principles and clinical advancements of muscle electrotransfer

    DEFF Research Database (Denmark)

    Hojman, Pernille

    2010-01-01

    Muscle electrotransfer covers the delivery of molecules to muscle tissue by means of electric pulses. This method has proven highly efficient in transferring, in particular, plasmid DNA to muscles, resulting in long-term expression of the transferred genes. DNA electrotransfer to muscle tissue has...

  14. Tips for leaders, part I: basic principles of leadership.

    Science.gov (United States)

    Harolds, Jay A

    2011-08-01

    There are many important leadership skills that can be learned from experience, mentoring, reading, discussions, lectures, etc. The subjects include not only business topics and communication skills but also a variety of tips on what to do and what not to do. These include desirable styles of leadership, how to gain the trust of others in the organization, the significance of the appropriate delegation of tasks, the importance of teams, how to manage change, how to win during a crisis, what to do in the early days of becoming a new leader, preventing the loss of one's practice to a rival organization, improving quality, and others. There are also many important attributes of leaders, including having a strong moral compass. Although each of these topics could be a book in of itself, this short series of articles will briefly examine these issues and others. PMID:21716023

  15. Basics principles of flat detector computed tomography (FD-CT)

    International Nuclear Information System (INIS)

    Flat detectors (FDs) have been developed for use in radiography and fluoroscopy to replace standard X-ray film, film-screen combinations and image intensifiers (II). In comparison to X-ray film and II, FD technology offers higher dynamic range, dose reduction, fast digital readout and the possibility for dynamic acquisitions of image series, yet keeping to a compact design. It appeared logical to employ FD designs also for computed tomography (CT) imaging. FDCT has meanwhile become widely accepted for interventional and intra-operative imaging using C-arm systems. Additionally, the introduction of FD technology was a milestone for soft-tissue CT imaging in the interventional suite which was not possible with II systems in the past. This review focuses on technical and performance issues of FD technology and its wide range of applications for CT imaging. FDCT is not aimed at challenging standard clinical CT as regards to the typical diagnostic examinations, but it has already proven unique for a number of dedicated CT applications offering distinct practical advantages, above all the availability of immediate CT imaging during an intervention. (orig.)

  16. Basic Principles of the System of Social Services and Assistance

    OpenAIRE

    Zhaklina Peto; Genta Bungo; Altina Xhoxhaj

    2011-01-01

    The desire to belong in a individual culture means to possess a clear vision for the world, a road map that guides its followers towards the proper understanding of the planet’s past present and future. An established mythology of apparent national identities in the Balkans is somewhat unnaturally reinforced to justify conflicts between religious and ethnic groups, caused as a result of the national identities intertwined among themselves, an element essentially more influential than existenc...

  17. Basic Principles of the System of Social Services and Assistance

    Directory of Open Access Journals (Sweden)

    Zhaklina Peto

    2011-01-01

    Full Text Available The desire to belong in a individual culture means to possess a clear vision for the world, a road map that guides its followers towards the proper understanding of the planet’s past present and future. An established mythology of apparent national identities in the Balkans is somewhat unnaturally reinforced to justify conflicts between religious and ethnic groups, caused as a result of the national identities intertwined among themselves, an element essentially more influential than existence of national identities. For centuries Christians and Muslims in the Balkans have been living in peace, however a few Balkan Societies continue to use violence, national extremism, xenophobia as well as a contemporary practice to solve their problems. A legitimate question can be raised in relation to how common is religious influence used to cause violent and armed conflicts as compared to violence originating from ethnic cleansing, control over territory, political ideology and regional hegemony?

  18. Radiology and the internet, basic principles and technical requirements

    International Nuclear Information System (INIS)

    As a new communication media the Internet has revolutionized the global exchange of information which is one of the major sources of progress in medicine. This article reviews the history of the Internet's evolution and describes some fundamental technical concepts. The importance of Internet services for everyday professional work is examined with special consideration of radiology. Special emphasis is laid on the current technical limitations that have delayed a broad practical implementation of tele-medical applications. As a highly innovative medical speciality, radiology has always been at the forefront of research and development in the field of clinical Internet applications. By taking a look at recent innovations, the impact of the Internet on the radiologist's working environment of the future is highlighted. (orig.)

  19. Extended Electrodynamics I. Basic Notions, Principles and Equations

    OpenAIRE

    Donev, S.; Tashkova, M.

    1997-01-01

    This paper aims to present an elaborate view on the motivation and realization of the idea to extend Maxwell's electrodynamics to Extended Electrodynamics in a reasonable and appropriate way in order to make it possible to describe electromagnetic (3+1)-soliton-like objects in vacuum and in the presence of continuous media (external fields), exchanging energy-momentum with the electromagnetic field.

  20. Basic safety principles and practice of WWERs in Hungary

    International Nuclear Information System (INIS)

    The nuclear safety is the actual subject of this presentation and it is considered to be the most important issue, and its permanent improvement is the key responsibility. We share the opinion, that everybody who works in the field of nuclear power generation has to be at such a high level, both in respect of the professional and the moral aspects, which would practically exclude occurrence of accidents causing adverse environmental effects. We are aware that another severe accident occurring in any country of the world would put the whole nuclear industry into a hopeless situation, which - as we have already seen - would seriously influence the Hungarian energy system as well. I try to illustrate in my presentation how can our WWER reactors be evaluated in the highlight of the internationally accepted safety requirements, how safe can they be considered and what can we do in order to ensure at every time the appropriate level of safety. 22 refs, 15 figs

  1. Is Nationality Basic or Cultural Need?

    Directory of Open Access Journals (Sweden)

    Aleksandras Gražvydas Jasmontas

    2011-03-01

    Full Text Available This article raises the question whether the nationality is ontological or cultural problem, that is to say, is nationality the sphere of necessity (basic human need or freedom (cultural need. With that aim, the matter concepts of basic human need and psychological (cultural need is disclosed, the principles formation of peoples and nations is carried out, the question of denationalization is raised. After all, is forming the conclusion that in history of development of nations and nationality these objects move from the sphere of nature (basic needs, that is to say, of necessity, to the sphere of culture (cultural needs, that is to say, of freedom.  

  2. Social Rights, Constitutionalism and the German Social State Principle

    OpenAIRE

    King, J. A.

    2014-01-01

    In this article I focus on the constitutional role of the German social state principle and the questions it generates for foreign jurists. Although the German Basic Law contains no set of social rights, the social state principle has invigorated readings of the basic rights constitutional provisions in a manner that invites comparison with, and raises the same competence questions, as the adjudication of social rights. On the other hand, the principle focuses on a general state duty to take ...

  3. Anatomy and Physiology of the Speech Mechanism.

    Science.gov (United States)

    Sheets, Boyd V.

    This monograph on the anatomical and physiological aspects of the speech mechanism stresses the importance of a general understanding of the process of verbal communication. Contents include "Positions of the Body,""Basic Concepts Linked with the Speech Mechanism,""The Nervous System,""The Respiratory System--Sound-Power Source,""The…

  4. Alfred-Adler's Basic Concepts and Implications.

    Science.gov (United States)

    Lundin, Robert W.

    This book presents the basic principles of Adler's psychology. The first chapter looks at Adlerian psychology as it exists today, and examines earlier influences. The second chapter examines feelings of inferiority and compensation for these feelings. The third chapter considers the nature of goals and how they are formulated. The fourth chapter…

  5. Atomic Energy Basics, Understanding the Atom Series.

    Science.gov (United States)

    Atomic Energy Commission, Oak Ridge, TN. Div. of Technical Information.

    This booklet is part of the "Understanding the Atom Series," though it is a later edition and not included in the original set of 51 booklets. A basic survey of the principles of nuclear energy and most important applications are provided. These major topics are examined: matter has molecules and atoms, the atom has electrons, the nucleus,…

  6. A Basic Guide to Nuclear Power.

    Science.gov (United States)

    Martocci, Barbara; Wilson, Greg

    More than 100 nuclear power plants supply over 17 percent of the electricity in the United States. The basic principles of how nuclear energy works and how it is used to make electricity are explained in this profusely illustrated booklet written for the average sixth grade reader. Discussions include: (1) atomic structure; (2) nuclear fission;…

  7. Virtual Immunology: Software for Teaching Basic Immunology

    Science.gov (United States)

    Berçot, Filipe Faria; Fidalgo-Neto, Antônio Augusto; Lopes, Renato Matos; Faggioni, Thais; Alves, Luiz Anastácio

    2013-01-01

    As immunology continues to evolve, many educational methods have found difficulty in conveying the degree of complexity inherent in its basic principles. Today, the teaching-learning process in such areas has been improved with tools such as educational software. This article introduces "Virtual Immunology," a software program available…

  8. Equivalence principles and electromagnetism

    Science.gov (United States)

    Ni, W.-T.

    1977-01-01

    The implications of the weak equivalence principles are investigated in detail for electromagnetic systems in a general framework. In particular, it is shown that the universality of free-fall trajectories (Galileo weak equivalence principle) does not imply the validity of the Einstein equivalence principle. However, the Galileo principle plus the universality of free-fall rotation states does imply the Einstein principle.

  9. Egalitarianism, basic structure and rawlsian contextualism

    Directory of Open Access Journals (Sweden)

    Cristián Fatauros

    2015-09-01

    Full Text Available This paper analyses whether it is appropriate to judge individual actions with the same principles of justice applicable to institutions. In order to achieve its aim the paper reviews Rawls` theory of justice and some objections against it. Critics of Rawlsian theory of justice deny that its principles only evaluate basic institutions. Furthermore, they claim that justice does not only require just institutions but just individual actions as well. The background hypothesis of this paper is that some principles suitable for some social contexts are not useful to judge other kind of social interactions. The argument relies on a normative interpretation of the notion of basic structure, which is considered a key element to defend the institutional character of the rawlsian account of justice.

  10. Deriving and applying generally applicable safety principles

    Energy Technology Data Exchange (ETDEWEB)

    Spray, S.D.

    1998-08-01

    The nuclear detonation safety of modern nuclear weapons depends on a coordinated safety theme incorporating three general safety principles: isolation, inoperability, and incompatibility. The success of this approach has encouraged them to study whether these and/or other principles might be useful in other applications. Not surprisingly, no additional first-principles (based on physical laws) have been identified. However, a more widely applicable definition and application of the principle-based approach has been developed, resulting in a selection of strategies that are basically subsets and varied combinations of the more general principles above. However, identification of principles to be relied on is only one step in providing a safe design. As one other important example, coordinating overall architecture and strategy is essential: the authors term this a safety theme.

  11. Physiological effects in aromatherapy

    Directory of Open Access Journals (Sweden)

    Tapanee Hongratanaworakit

    2004-01-01

    Full Text Available The effects of aromas on humans are divided into physiological and psychological effects. The physiological effect acts directly on the physical organism, the psychological effect acts via the sense of smell or olfactory system, which in turn may cause a physiological effect. This paper reviews on the physiological effects which are used for the evaluation of the effects of aromas. Physiological parameters, i.e. heart rate blood pressure, electrodermal activity, electroencephalogram, slow potential brain waves (contingent negativevariation, and eye blink rate or pupil functions, are used as indices for the measurement of the aroma effects

  12. The principles of adversarial procedure and equality in international commercial arbitration

    OpenAIRE

    Козирєва, Валентина; Гаврилішин, Анатолій

    2016-01-01

    The article investigates the principles of competitiveness and procedural equality as basic principles of justice which govern litigation international commercial arbitration. On the basis of international legal acts are examples of the application of the above principles. English abstract V. Kozyreva, A. Havrylishyn The article deals with the principles of competition and equality of procedural justice as the basic principles governing the cases to international commercial arbitration. On...

  13. Basic Research Firing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Basic Research Firing Facility is an indoor ballistic test facility that has recently transitioned from a customer-based facility to a dedicated basic research...

  14. Health Insurance Basics

    Science.gov (United States)

    ... Can I Help a Friend Who Cuts? Health Insurance Basics KidsHealth > For Teens > Health Insurance Basics Print ... advanced calculus was confusing. What Exactly Is Health Insurance? Health insurance is a plan that people buy ...

  15. Climate Change: Basic Information

    Science.gov (United States)

    ... are here: EPA Home Climate Change Basic Information Climate Change: Basic Information On This Page Climate change ... We can make a difference How is the climate changing in the U.S.? Observations across the United ...

  16. Principles and management of adrenal cancer

    International Nuclear Information System (INIS)

    Principles and Management of Adrenal Cancer is a comprehensive presentation of the medical and surgical management of neoplastic diseases of the adrenal glands. It consists of two parts. The first provides an overview of the embryology, anatomy, physiology, pathology, and advances in methods of diagnosis and imaging techniques. The second deals with specific diseases of the adrenal cortex and medulla. (orig./MG)

  17. A hybrid approach to advancing quantitative prediction of tissue distribution of basic drugs in human

    International Nuclear Information System (INIS)

    A general toxicity of basic drugs is related to phospholipidosis in tissues. Therefore, it is essential to predict the tissue distribution of basic drugs to facilitate an initial estimate of that toxicity. The objective of the present study was to further assess the original prediction method that consisted of using the binding to red blood cells measured in vitro for the unbound drug (RBCu) as a surrogate for tissue distribution, by correlating it to unbound tissue:plasma partition coefficients (Kpu) of several tissues, and finally to predict volume of distribution at steady-state (Vss) in humans under in vivo conditions. This correlation method demonstrated inaccurate predictions of Vss for particular basic drugs that did not follow the original correlation principle. Therefore, the novelty of this study is to provide clarity on the actual hypotheses to identify i) the impact of pharmacological mode of action on the generic correlation of RBCu-Kpu, ii) additional mechanisms of tissue distribution for the outlier drugs, iii) molecular features and properties that differentiate compounds as outliers in the original correlation analysis in order to facilitate its applicability domain alongside the properties already used so far, and finally iv) to present a novel and refined correlation method that is superior to what has been previously published for the prediction of human Vss of basic drugs. Applying a refined correlation method after identifying outliers would facilitate the prediction of more accurate distribution parameters as key inputs used in physiologically based pharmacokinetic (PBPK) and phospholipidosis models.

  18. Body Basics Library

    Science.gov (United States)

    ... a Friend Who Cuts? About the Body Basics Library KidsHealth > For Teens > About the Body Basics Library Print A A A Text Size Did you ... system, part, and process works. Use this medical library to find out about basic human anatomy, how ...

  19. Basic Cake Decorating Workbook.

    Science.gov (United States)

    Bogdany, Mel

    Included in this student workbook for basic cake decorating are the following: (1) Drawings of steps in a basic way to ice a layer cake, how to make a paper cone, various sizes of flower nails, various sizes and types of tin pastry tubes, and special rose tubes; (2) recipes for basic decorating icings (buttercream, rose paste, and royal icing);…

  20. Manual on brachytherapy. Incorporating: Applications guide, procedures guide, basics guide

    International Nuclear Information System (INIS)

    In addition to a basic guide to the principles of the production of ionizing radiation and to methods of radiation protection and dosimetry, this booklet includes information about radiation protection procedures for brachytherapy

  1. Contribution of Ayurveda in foundation of basic tenets of bioethics.

    Science.gov (United States)

    Tawalare, Kiran A; Nanote, Kalpana D; Gawai, Vijay U; Gotmare, Ashish Y

    2014-01-01

    Ethics deal with the set of principles of right conduct. The four basic principles of bioethics - autonomy, beneficence, non-maleficence and justice are known as "principlism". Though these four principles are influenced by the western world; in the medical field they are adapted as universal ethics. Originally, Ayurveda, the Indian medical system, has strongly advocated ethical code of conduct for physicians, but does not get its due recognition till this date. Proposed article aims to compare universally accepted basic tenets of bioethics and ancient Ayurvedic ethics. For this purpose classical texts of Ayurveda and literature regarding principlism was collected and analyzed thoroughly. It was found that the essence of ethics is very well-defined and described in the fundamental texts of Ayurveda in the form of Sadvritta, Chatushpada, Yogya, Vaidyavritti and Aachara Rasayana. Hence, Ayurveda should be considered as a trailblazer in establishing the basic tenets of bioethics. PMID:26195897

  2. Principle of criminal legality as a fundamental human right

    OpenAIRE

    Hoffmann Monteiro de Castro, Henrique

    2012-01-01

    This work aims to discuss the principle of legality in criminal law, principle qualified as a fundamental human right. The criminal legality is a natural guarantee of citizens, having basic character in any state that pretends itself democratic, reflecting main feature of the legal systems based on justice and rationality. As it is clear that the principle of legality seems to be a constitutional guarantee of individual, its analysis is essential for understanding a principled view of the cri...

  3. Beginning Visual Basic 2010

    CERN Document Server

    Willis, Thearon

    2010-01-01

    A focused, step-by-step approach to Visual Basic for new programmers. What better way to get started with Visual Basic than with this essential Wrox beginner's guide? Beginning Microsoft Visual Basic 2010 not only shows you how to write Windows applications, Web applications with ASP.NET, and Windows mobile and embedded CE apps with Visual Basic 2010, but you'll also get a thorough grounding in the basic nuts-and-bolts of writing good code. You'll be exposed to the very latest VB tools and techniques with coverage of both the Visual Studio 2010 and .NET 4 releases. Plus, the book walks you ste

  4. The Caux Round Table principles for business.

    Science.gov (United States)

    Curtin, L L

    1996-02-01

    In 1994, the Caux Round Table in Switzerland developed what is believed to be the first international code of business ethics. Business leaders from Japan, Europe and the United States collaborated to create a set of principles rooted in two basic ideals: kyosei and human dignity. Because of its importance and its applicability to the conduct of today's health care businesses, this entire column is devoted to reprinting these "Principles for Business." PMID:8632875

  5. Accounting Principles are Simulated on Quantum Computers

    OpenAIRE

    Diep, Do Ngoc; Giang, Do Hoang

    2005-01-01

    The paper is devoted to a new idea of simulation of accounting by quantum computing. We expose the actual accounting principles in a pure mathematics language. After that we simulated the accounting principles on quantum computers. We show that all arbitrary accounting actions are exhausted by the described basic actions. The main problem of accounting are reduced to some system of linear equations in the economic model of Leontief. In this simulation we use our constructed quantum Gau\\ss-Jor...

  6. Validating the effectiveness of Clinically Oriented Physiology Teaching (COPT) in undergraduate physiology curriculum

    OpenAIRE

    Ramnarayan Komattil; Abraham Reem; Kamath Asha

    2008-01-01

    Abstract Background It has been proved that basic science knowledge learned in the context of a clinical case is actually better comprehended and more easily applied by medical students than basic science knowledge learned in isolation. The present study intended to validate the effectiveness of Clinically Oriented Physiology Teaching (COPT) in undergraduate medical curriculum at Melaka Manipal Medical College (Manipal Campus), Manipal, India. Methods COPT was a teaching strategy wherein, stu...

  7. THE IMPORTANCE OF MULTIMEDIA PRINCIPLE AND EMERGENCE PRINCIPLE FOR THE KNOWLEDGE CIVILISATION AGE

    Institute of Scientific and Technical Information of China (English)

    Andrzej P. WIERZBICKI; Yoshiteru NAKAMORI

    2008-01-01

    The paper discusses two basic principles derived from results of studies concerning foundations of micro-theories of knowledge creation; these are Multimedia Principle and Emergence Principle. Their epistemic, systemic and metaphysical importance is discussed, together with their relations to the episteme of technology treated as a separate cultural sphere. A spiral of evolutionary knowledge creation is presented, in which an extended Falsification Principle plays the role of an objectifying feedback; this spiral is related to an episteme of Evolutionary Constructive Objectivism proposed earlier for the coming knowledge civilisation age.

  8. Chewing over physiology integration.

    Science.gov (United States)

    Abdulkader, Fernando; Azevedo-Martins, Anna Karenina; Miranda, Manoel de Arcisio; Brunaldi, Kellen

    2005-03-01

    An important challenge for both students and teachers of physiology is to integrate the different areas in which physiological knowledge is didactically divided. In developing countries, such an issue is even more demanding, because budget restrictions often affect the physiology program with laboratory classes being the first on the list when it comes to cuts in expenses. With the aim of addressing this kind of problem, the graduate students of our department organized a physiology summer course offered to undergraduate students. The objective was to present the different physiological systems in an integrated fashion. The strategy pursued was to plan laboratory classes whose experimental results were the basis for the relevant theoretical discussions. The subject we developed to illustrate physiology integration was the study of factors influencing salivary secretion. PMID:15718383

  9. The analysis of pricing principles at domestic industrial enterprises

    Directory of Open Access Journals (Sweden)

    I.M. Rjabchenko

    2013-03-01

    Full Text Available The analysis of pricing principles at domestic industrial enterprisesTheoretical and methodological aspects of marketing pricing formation are investigated in the article. The aim of this research is systematization of marketing pricing principles and formation of corresponding offers concerning perfection of a domestic industrial enterprises pricing policy.The results of the analysis. The authors note that pricing principles are important element of pricing methodology which form basic positions, characteristics for all pricing system. The essence of such pricing principles as scientific substantiation of prices, target direction of prices, unity principle of pricing process, principle of continuous pricing process, interrelation between pricing policy and general enterprise strategy, principle of legality, planned character, proportionality, adequacy, principle of interdependence between types and forms of selling, flexibility principle is considered.The table of the resulted principles allows us to group them after the followings descriptions:general principles: planned character principle, principle of legality, principle of proportionality, principle of adequacy, principle of flexibility;main principles: principle of scientific prices substantiation, principle of prices target direction, unity principle of pricing process, principle of continuous pricing process;specific principles: principle of connection between pricing policy and general strategy of enterprise, principle of interrelation between types and forms of selling, principle connected with the features of products which will be distribute, principle connected with buyers quality maintenance;individual principles: principle connected with market structure, principle that applies to the choice of reaction type and market conditions change and so on.Conclusions and directions of further researches. Research of theoretical and methodological aspects of marketing pricing forming

  10. Basics of Bayesian Learning - Basically Bayes

    DEFF Research Database (Denmark)

    Larsen, Jan

    Tutorial presented at the IEEE Machine Learning for Signal Processing Workshop 2006, Maynooth, Ireland, September 8, 2006. The tutorial focuses on the basic elements of Bayesian learning and its relation to classical learning paradigms. This includes a critical discussion of the pros and cons. The...

  11. Osnovni principi, metodološki pristup CORINE Land Cover u BiH i analiza rezultata CLC2000 i CLC2006 : Basic principles, a methodological approach CORINE Land Cover in b&h and analysis of results CLC2000 and CLC2006

    Directory of Open Access Journals (Sweden)

    Jasmin Taletović

    2012-06-01

    Full Text Available Prikazani su osnovni principi, metodološki pristup CORINE Land Cover–revizija i korekcija CORINE land cover u BiH (prvi inventar i priprema CLC2006 baze podataka. Projekat CORINE Land Cover 2006 u Bosni i Hercegovini (CLC2000 i CLC2006 korišten je kao glavni izvor podataka u ovom radu. Posebna pažnja je usmjerena na metod identifikacije promjena u načinu korištenja zemljišta, odnosno na zemljišnom pokrivaču u periodu 2000-2006. Obzirom da su promjene načina korištenja zemljišta pripremljene u GIS-u, u ovom radu GIS je prikazan kao alat, kao i različite mogućnosti ovog alata u pogledu analize podataka. Predstavljena je mogućnost upotrebe CORINE 2006 u procesima planiranja korištenja zemljišta u BiH predstavljena. : Basic principles, methodological approach to the CORINE Land Cover database–revision and correction of the CORINE 2000 (the first inventory and preparation of the CLC2006 database are shown. The CORINE Land Cover 2006 project in Bosnia and Herzegovina (CLC2000 and CLC2006 is used as a main source of data in this paper. Special attention will be given to the metodological approach in identifying land use changes, land cover between 2000-2006. Bearing in mind that land use changes have been produced by using GIS technology, this work present GIS as a tool, while various possibilities of this tool regarding data analysis presented as well. The possibility of using the CORINE 2006 in land use planning processes in B&H is presented.

  12. Basic molecular spectroscopy

    CERN Document Server

    Gorry, PA

    1985-01-01

    BASIC Molecular Spectroscopy discusses the utilization of the Beginner's All-purpose Symbolic Instruction Code (BASIC) programming language in molecular spectroscopy. The book is comprised of five chapters that provide an introduction to molecular spectroscopy through programs written in BASIC. The coverage of the text includes rotational spectra, vibrational spectra, and Raman and electronic spectra. The book will be of great use to students who are currently taking a course in molecular spectroscopy.

  13. Basic methodical concept of engineering safety

    International Nuclear Information System (INIS)

    The determination and assessment of technical risks constitute the basis for setting safety standards which should be guided by the principle of similarly low risks in comparable situations. Safety science cannot yet provide international standardization efforts with a complete basic methodical concept promising enough to be universally recognized. For causally substantiated risks, the methodical instrument of risk comparison seems to be best suited as an optimization principle. For causally not removable imponderabilities, no risk comparisons are possible. Such cases can only be judged by opportunity, because their non-causal character does not stand scientific treatment. (orig.)

  14. Basic mechanisms of asthma.

    OpenAIRE

    Boushey, H A; Fahy, J.V.

    1995-01-01

    Results of studies of the epidemiology, physiology, histopathology, and cell biology of asthma have revised our conception of the disease. Epidemiologic studies have shown asthma to be an important cause of death, suffering, and economic hardship. Physiologic studies have shown that asthma is a chronic illness characterized by persistent bronchial hyperreactivity. Histopathologic studies have shown characteristic changes: epithelial damage, deposition of collagen beneath the basement membrane...

  15. Industrial instrumentation principles and design

    CERN Document Server

    Padmanabhan, Tattamangalam R

    2000-01-01

    Pneumatic, hydraulic and allied instrumentation schemes have given way to electronic schemes in recent years thanks to the rapid strides in electronics and allied areas. Principles, design and applications of such state-of-the-art instrumentation schemes form the subject matter of this book. Through representative examples, the basic building blocks of instrumentation schemes are identified and each of these building blocks discussed in terms of its design and interface characteristics. The common generic schemes synthesized with such building blocks are dealt with subsequently. This forms the scope of Part I. The focus in Part II is on application. Displacement and allied instrumentation, force and allied instrumentation and process instrumentation in terms of temperature, flow, pressure level and other common process variables are dealt with separately and exhaustively. Despite the diversity in the sensor principles and characteristics and the variety in the applications and their environments, it is possib...

  16. Advances in physiological computing

    CERN Document Server

    Fairclough, Stephen H

    2014-01-01

    This edited collection will provide an overview of the field of physiological computing, i.e. the use of physiological signals as input for computer control. It will cover a breadth of current research, from brain-computer interfaces to telemedicine.

  17. Phun Week: Understanding Physiology

    Science.gov (United States)

    Limson, Mel; Matyas, Marsha Lakes

    2009-01-01

    Topics such as sports, exercise, health, and nutrition can make the science of physiology relevant and engaging for students. In addition, many lessons on these topics, such as those on the cardiovascular, respiratory, and digestive systems, align with national and state life science education standards. Physiology Understanding Week (PhUn…

  18. Reproduction, Physiology and Biochemistry

    Science.gov (United States)

    This chapter focuses on the reproduction, physiology, and biochemistry of the root-knot nematodes. The extensive amount of information on the reproduction and cytogenetics of species of Meloidogyne contrasts with the limited information on physiology, biochemistry, and biochemical pathways. In commo...

  19. Radiation protection principles of NCRP.

    Science.gov (United States)

    Kase, Kenneth R

    2004-09-01

    The current recommendations of the National Council on Radiation Protection and Measurements (NCRP) relative to ionizing radiation are based on radiation protection principles that developed historically as information about radiation effects on human populations became available. Because the NCRP Charter states that the NCRP will cooperate with the International Commission on Radiological Protection (ICRP), the basic principles and recommendations for radiation protection of the NCRP are closely coupled with those of the ICRP. Thus, the fundamental principles of justification, optimization, and dose limitation as initially stated in ICRP Publication 26 have been adopted and applied by the NCRP in its recommendations. ICRP and NCRP recommendations on dose limitation for the general public and for occupationally exposed individuals are based on the same analyses of radiation risk, and, while similar, there are differences reflecting the aspects of radiation application and exposure circumstances unique to the United States. The NCRP has recently extended its guidance to address exposure to individuals engaged in space activities. Several reports have been issued or are in preparation to provide recommendations on dose limitation and the development of radiation safety programs to apply the radiation protection principles in space activities. The biological basis for these recommendations is provided in these and accompanying NCRP reports. Recommendations for the application of basic radiation protection principles have been made in many reports over the years. Those that are most current appear in approximately 50 reports published in the last 15 y. These address radiation safety practices in industrial and medical institutions, control of radionuclides in the environment, protection of the public, and assessment of radiation risk. Some of the aspects of these recommendations will be discussed. Current recommendations related to radiation safety practice are based

  20. Slurry flow principles and practice

    CERN Document Server

    Shook, C A; Brenner, Howard

    2015-01-01

    Slurry Flow: Principles and Practice describes the basic concepts and methods for understanding and designing slurry flow systems, in-plan installations, and long-distance transportation systems. The goal of this book is to enable the design or plant engineer to derive the maximum benefit from a limited amount of test data and to generalize operating experience to new situations. Design procedures are described in detail and are accompanied by illustrative examples needed by engineers with little or no previous experience in slurry transport.The technical literature in this field is extensive:

  1. Nonlinear Optics: Principles and Applications

    DEFF Research Database (Denmark)

    Rottwitt, Karsten; Tidemand-Lichtenberg, Peter

    As nonlinear optics further develops as a field of research in electromagnetic wave propagation, its state-of-the-art technologies will continue to strongly impact real-world applications in a variety of fields useful to the practicing scientist and engineer. From basic principles to examples of...... nonlinear phenomena, it describes nonlinear wave propagation in bulk and in waveguiding structures, and includes specific examples of applied nonlinear wave propagation through crystals, optical waveguides, and optical fibers. Providing a theoretical description of nonlinear interaction between light and...

  2. Exponentiation: A New Basic?

    Science.gov (United States)

    Davis, Brent

    2015-01-01

    For centuries, the basic operations of school mathematics have been identified as addition, subtraction, multiplication, and division. Notably, these operations are "basic," not because they are foundational to mathematics knowledge, but because they were vital to a newly industrialized and market-driven economy several hundred years…

  3. Turkey's Basic Education Programme

    OpenAIRE

    A. Remzi Sezgin

    2000-01-01

    In August 1997, the Government of Turkey greatly increased its efforts to implement eight-year obligatory education, through parliamentary approval of Law No. 4306 for Basic Education. The law mobilises significant resources for a major investment in school facilities through earmarked taxes, establishes a timetable for the Basic Education Programme and streamlines procedures to allow for swift action and implementation.

  4. Bracken Basic Concept Scale.

    Science.gov (United States)

    Naglieri, Jack A.; Bardos, Achilles N.

    1990-01-01

    The Bracken Basic Concept Scale, for use with preschool and primary-aged children, determines a child's school readiness and knowledge of English-language verbal concepts. The instrument measures 258 basic concepts in such categories as comparisons, time, quantity, and letter identification. This paper describes test administration, scoring and…

  5. Basic Research Objectives Reaffirmed

    Institute of Scientific and Technical Information of China (English)

    Guo Haiyan; Zhao Baohua

    2002-01-01

    @@ As a national institution for scientific research and a component of the national innovation system, CAS should and must make key contributions to the great national rejuvenation of the country. Keeping this in mind, CAS has developed four developmental targets for its basic research. This was revealed at a CAS conference on basic research held June 11-12 in Beijing.

  6. Isolated muscle cells as a physiological model.

    Science.gov (United States)

    Lieberman, M; Hauschka, S D; Hall, Z W; Eisenberg, B R; Horn, R; Walsh, J V; Tsien, R W; Jones, A W; Walker, J L; Poenie, M

    1987-09-01

    Summary of a symposium presented by the American Physiological Society (Cell and General Physiology Section and Muscle Group) at the 70th Annual Meeting of the Federation of American Societies for Experimental Biology, St. Louis, Missouri, April 15, 1986, chaired by M. Lieberman and F. Fay. This symposium reflects a growing interest in seeking new technologies to study the basic physiological and biophysical properties of cardiac, smooth, and skeletal muscle cells. Recognizing that technical and analytical problems associated with multicellular preparations limit the physiological significance of many experiments, investigators have increasingly focused on efforts to isolate single, functional embryonic, and adult muscle cells. Progress in obtaining physiologically relevant preparations has been both rapid and significant even though problems regarding cell purification and viability are not fully resolved. The symposium draws attention to a broad, though incomplete, range of studies using isolated or cultured muscle cells. Based on the following reports, investigators should be convinced that a variety of experiments can be designed with preparations of isolated cells and those in tissue culture to resolve questions about fundamental physiological properties of muscle cells. PMID:2443014

  7. Optical coherence tomography. Development, principles, applications

    Energy Technology Data Exchange (ETDEWEB)

    Fercher, Adolf Friedrich [Medizinische Univ. Wien, Vienna (Austria). ZBMTP - Medizinische Physik

    2010-07-01

    This paper presents a review of the development of optical coherence tomography (OCT), its principles and important applications. Basic OCT systems are described and the physical foundations of OCT signal properties and signal recording systems are reviewed. Recent examples of OCT applications in ophthalmology, cardiology, gastroenterology and dermatology outline the relevance of this advanced imaging modality in the medical field. (orig.)

  8. Drying principles and theory: An overview

    International Nuclear Information System (INIS)

    A comprehensive review of the fundamental principles and theories governing the drying process is presented. Basic definitions are given. The development of contemporary models of drying of agricultural products are traced from the earliest reported sorption and moisture equilibrium models, through the single kernel of product models to the thin layer and deep bed drying analysis. (author). 29 refs, 10 figs

  9. Beyond the Virtues-Principles Debate.

    Science.gov (United States)

    Keat, Marilyn S.

    1992-01-01

    Indicates basic ontological assumptions in the virtues-principles debate in moral philosophy, noting Aristotle's and Kant's fundamental ideas about morality and considering a hermeneutic synthesis of theories. The article discusses what acceptance of the synthesis might mean in the theory and practice of moral pedagogy, offering examples of…

  10. Safety principles and design management of Chashma Nuclear Power Plant

    International Nuclear Information System (INIS)

    The basic safety consideration and detailed design principles in the design of Chashma Nuclear Power Plant is elaborated. The management within the frame setting up by 'safety culture' and 'quality culture'

  11. Computer graphics from basic to application

    International Nuclear Information System (INIS)

    This book mentions conception of computer graphics, background history, necessity and applied field like construction design, image processing, auto mobile design, fashion design and TV broadcast, basic principle of computer, computer graphics hardware, computer graphics software such as adobe illustrator tool box and adobe photo shop, quarkXpress like introduction, application and operating circumstance, 3D graphics with summary, difference of versions of 3D studio and system, and Auto CAD application.

  12. Cyber-security curricula for basic users

    OpenAIRE

    Zepf, Arthur L.,IV

    2013-01-01

    Approved for public release; distribution is unlimited There have been only a small number of attempts at creating a cyber-security curriculum that can be used to teach children the concepts of cyber security and information assurance. There is a significant shortage of attempts at creating a computer-security curricula and cyber-security training for people who have only basic computer skills. Also, the integration of computer-security and information assurance principles into formal and ...

  13. Back to basics: hand hygiene and isolation

    OpenAIRE

    Lin Huang, G. Khai; Stewardson, Andrew J; Lindsay Grayson, M.

    2014-01-01

    Purpose of review Hand hygiene and isolation are basic, but very effective, means of preventing the spread of pathogens in healthcare. Although the principle may be straightforward, this review highlights some of the controversies regarding the implementation and efficacy of these interventions. Recent findings Hand hygiene compliance is an accepted measure of quality and safety in many countries. The evidence for the efficacy of hand hygiene in directly reducing rates of hospital-acquired in...

  14. Classical Liberalism and the Basic Income

    OpenAIRE

    Zwolinski Matt

    2012-01-01

    This article provides a brief overview of the relationship between libertarian political theory and the Basic Income (BI). It distinguishes between different forms of libertarianism and argues that at least one form, classical liberalism, is compatible with and provides some grounds of support for BI. A classical liberal BI, however, is likely to be much smaller than the sort of BI defended by those on the political left. And there are both contingent-empirical and principled-moral reasons fo...

  15. Directed basic research

    International Nuclear Information System (INIS)

    In its execution, and in the requirement of no other deliverables than knowledge generation, directed basic research is no different from conventional (self-directed) basic research. The selected areas are determined in a national perspective. Directed Basic Research may be in an area where the knowledge generation would benefit Indian Society in the long term, or it may be in an area where the results of the research would benefit Indian Industry or our strategic interests in the long term. India can become a global innovation leader provided we have technology foresight to make the right technology choices, provided we introduce coherent synergy (a phrase I coined a few years back in this context) in our science and technology related activities and provided we establish an effective innovation ecosystem. We must also selectively promote some technology areas through directed basic research. Sustainable economic development in the future requires strong and increased funding of basic research. While directed basic research should be encouraged, self-directed basic research should also receive substantially increased support. (author)

  16. Clinical Physiology: A Successful Academic and Clinical Discipline is Threatened in Sweden

    Science.gov (United States)

    Arheden, Hakan

    2009-01-01

    Clinical physiologists in Sweden are physicians (the majority with a PhD degree) with thorough training in system physiology and pathophysiology. They investigate patients in a functional approach and are engaged in basic and applied physiology teaching and research. In 1954, clinical physiology was founded as an independent academic and clinical…

  17. Chemical Principls Exemplified

    Science.gov (United States)

    Plumb, Robert C.

    1973-01-01

    Two topics are discussed: (1) Stomach Upset Caused by Aspirin, illustrating principles of acid-base equilibrium and solubility; (2) Physical Chemistry of the Drinking Duck, illustrating principles of phase equilibria and thermodynamics. (DF)

  18. Basic stress analysis

    CERN Document Server

    Iremonger, M J

    2013-01-01

    BASIC Stress Analysis aims to help students to become proficient at BASIC programming by actually using it in an important engineering subject. It also enables the student to use computing as a means of learning stress analysis because writing a program is analogous to teaching-it is necessary to understand the subject matter. The book begins by introducing the BASIC approach and the concept of stress analysis at first- and second-year undergraduate level. Subsequent chapters contain a summary of relevant theory, worked examples containing computer programs, and a set of problems. Topics c

  19. Basics of averaging of the Maxwell equations

    CERN Document Server

    Chipouline, A; Tretyakov, S

    2011-01-01

    Volume or statistical averaging of the microscopic Maxwell equations (MEs), i.e. transition from microscopic MEs to their macroscopic counterparts, is one of the main steps in electrodynamics of materials. In spite of the fundamental importance of the averaging procedure, it is quite rarely properly discussed in university courses and respective books; up to now there is no established consensus about how the averaging procedure has to be performed. In this paper we show that there are some basic principles for the averaging procedure (irrespective to what type of material is studied) which have to be satisfied. Any homogenization model has to be consistent with the basic principles. In case of absence of this correlation of a particular model with the basic principles the model could not be accepted as a credible one. Another goal of this paper is to establish the averaging procedure for metamaterials, which is rather close to the case of compound materials but should include magnetic response of the inclusi...

  20. Specifics of metallurgical industry for implementation of lean principles

    Directory of Open Access Journals (Sweden)

    A. Samolejová

    2012-07-01

    Full Text Available The ideal balance between innovating and effective financing is provided by the Lean principles. The basic principle of Lean is to eliminate the wastes and to increase the efficiency of production processes. The objective of this article is to define the basic specifics of metallurgical production, to analyze the classical sources of wastes (Ohno’s seven wastes from the point of view of the identified specifics and to propose the priorities for their elimination in metallurgical production.